40 CFR 258.52 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false [Reserved] 258.52 Section 258.52 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.52 [Reserved] ...

Antibody-Mediated Killing of Carbapenem-Resistant ST258 Klebsiella pneumoniae by Human Neutrophils

PubMed Central

Kobayashi, Scott D.; Porter, Adeline R.; Freedman, Brett; Pandey, Ruchi; Chen, Liang; Kreiswirth, Barry N.

2018-01-01

ABSTRACT Carbapenem-resistant Klebsiella pneumoniae is a problem worldwide. A carbapenem-resistant K. pneumoniae lineage classified as multilocus sequence type 258 (ST258) is prominent in the health care setting in many regions of the world, including the United States. ST258 strains can be resistant to virtually all clinically useful antibiotics; treatment of infections caused by these organisms is difficult, and mortality is high. As a step toward promoting development of new therapeutics for ST258 infections, we tested the ability of rabbit antibodies specific for ST258 capsule polysaccharide to enhance human serum bactericidal activity and promote phagocytosis and killing of these bacteria by human neutrophils. We first demonstrated that an isogenic wzy deletion strain is significantly more susceptible to killing by human heparinized blood, serum, and neutrophils than a wild-type ST258 strain. Consistent with the importance of capsule as an immune evasion molecule, rabbit immune serum and purified IgG specific for ST258 capsule polysaccharide type 2 (CPS2) enhanced killing by human blood and serum in vitro. Moreover, antibodies specific for CPS2 promoted phagocytosis and killing of ST258 by human neutrophils. Collectively, our findings suggest that ST258 CPS2 is a viable target for immunoprophylactics and/or therapeutics. PMID:29535199

Genomic Analysis of the Emergence and Rapid Global Dissemination of the Clonal Group 258 Klebsiella pneumoniae Pandemic

PubMed Central

Driebe, Elizabeth M.; MacCannell, Duncan R.; Roe, Chandler; Lemmer, Darrin; de Man, Tom; Rasheed, J. Kamile; Engelthaler, David M.; Keim, Paul; Limbago, Brandi M.

2015-01-01

Multidrug-resistant Klebsiella pneumoniae producing the KPC carbapenemase have rapidly spread throughout the world, causing severe healthcare-associated infections with limited antimicrobial treatment options. Dissemination of KPC-producing K. pneumoniae is largely attributed to expansion of a single dominant strain, ST258. In this study, we explore phylogenetic relationships and evolution within ST258 and its clonal group, CG258, using whole genome sequence analysis of 167 isolates from 20 countries collected over 17 years. Our results show a common ST258 ancestor emerged from its diverse parental clonal group around 1995 and likely acquired bla KPC prior to dissemination. Over the past two decades, ST258 has remained highly clonal despite diversity in accessory elements and divergence in the capsule polysaccharide synthesis locus. Apart from the large recombination event that gave rise to ST258, few mutations set it apart from its clonal group. However, one mutation occurs in a global transcription regulator. Characterization of outer membrane protein sequences revealed a profile in ST258 that includes a truncated OmpK35 and modified OmpK37. Our work illuminates potential genomic contributors to the pathogenic success of ST258, helps us better understand the global dissemination of this strain, and identifies genetic markers unique to ST258. PMID:26196384

40 CFR 258.27 - Surface water requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Surface water requirements. 258.27 Section 258.27 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.27 Surface water requirements. MSWLF...

Performance of a PCR assay for the rapid identification of the Klebsiella pneumoniae ST258 epidemic clone in Latin American clinical isolates.

PubMed

Gomez, S A; Rapoport, M; Piergrossi, N; Faccone, D; Pasteran, F; De Belder, D; ReLAVRA-Group; Petroni, A; Corso, A

2016-10-01

The worldwide dissemination of Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae ST258 demands a rapid PCR-based typing method to detect unique genes of the ST258 clone. This study evaluates a PCR developed by Adler et al. (2014) for the detection of ST258 in K. pneumoniae clinical isolates centered on the identification of the pilv-I and prp genes. We tested 143 clinical isolates from Argentina (n=109), Chile (n=1), Colombia (n=1), Costa Rica (n=2), Ecuador (n=5), El Salvador (n=2), Nicaragua (n=5), Panamá (n=2), Paraguay (n=2), Perú (n=3) and Trinidad and Tobago (n=11) recovered from 2006 to 2015. blaKPC, pilv-l and prp genes were detected by PCR and sequenced by standard procedures. ST258 and non-ST258 were defined by PFGE and/or MLST. Isolates were grouped according to PFGE patterns: 58 were compatible with ST258 (group 1) and 85 with non-ST258 (group 2). MLST study was done on an arbitrary selection of isolates. The pilv-l gene was present only in ST258 isolates, regardless of the presence of the blaKPC gene. Results for the prp gene were variable. Its presence did not define ST258. The pilv-I PCR had a sensitivity and specificity of 100%, respectively, for the detection of ST258 in the isolates under investigation. Given our findings, the pilv-I PCR could replace more time and resource consuming methods, allowing for more rapid detection of the circulating high risk K. pneumoniae clone ST258 in Latin American (LA) countries. Copyright © 2016 Elsevier B.V. All rights reserved.

Repulsion between Lys258 and upstream arginines explains the missorting of the AQP2 mutant p.Glu258Lys in nephrogenic diabetes insipidus.

PubMed

Kamsteeg, Erik-Jan; Stoffels, Monique; Tamma, Grazia; Konings, Irene B M; Deen, Peter M T

2009-10-01

Regulation of body water homeostasis occurs by the vasopressin-dependent sorting of aquaporin-2 (AQP2) water channels to and from the apical membrane of renal principal cells. Mutations in AQP2 cause autosomal nephrogenic diabetes insipidus (NDI), a disease that renders the kidney unresponsive to vasopressin, resulting in polyuria and polydipsia. The AQP2 mutant c.772G>A; p.Glu258Lys (AQP2-E258K) causes dominant NDI by oligomerizing with wild-type AQP2 and missorting of this AQP2 complex to multivesicular bodies instead of the apical membrane. The motif causing this missorting of AQP2-E258K was identified here. Functional analyses and plasma membrane expression studies of truncation mutants in oocytes revealed that AQP2-E258K shortened to Leu259 is still intracellular retained. Alanine scanning and glutamic acid to arginine exchanges revealed increased function and plasma membrane expression for AQP2-E258K mutants with the following additional changes: Leu259Ala, Arg252Glu, Arg253Glu, or Arg252Ala-Arg254Ala, or for the AQP2 mutant p.Glu258Ala, indicating that the motif RRRxxxK(258)L confers AQP2-E258K retention. Fusion of this motif to aquaporin-1 also resulted in missorting of that water channel, indicating that this retention motif is transferable. In conclusion, our data reveal that the RRRxxxKL motif and repulsion between K258 and the arginine-triplet within this motif are the primary cause of missorting of AQP2-E258K in NDI.

20 CFR 632.258 - Allowable activities.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Allowable activities. 632.258 Section 632.258 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INDIAN AND NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.258 Allowable activities...

20 CFR 632.258 - Allowable activities.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Allowable activities. 632.258 Section 632.258 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INDIAN AND NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.258 Allowable activities...

20 CFR 632.258 - Allowable activities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Allowable activities. 632.258 Section 632.258 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR INDIAN AND NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.258 Allowable activities...

40 CFR 258.50 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Applicability. 258.50 Section 258.50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL... and environment. (c) Owners and operators of MSWLF units, except those meeting the conditions of § 258...

40 CFR 258.10 - Airport safety.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Airport safety. 258.10 Section 258.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Location Restrictions § 258.10 Airport safety. (a) Owners or operators of new...

40 CFR 258.15 - Unstable areas.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Unstable areas. 258.15 Section 258.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Location Restrictions § 258.15 Unstable areas. (a) Owners or operators of new...

40 CFR 258.10 - Airport safety.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Airport safety. 258.10 Section 258.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Location Restrictions § 258.10 Airport safety. (a) Owners or operators of new...

40 CFR 258.15 - Unstable areas.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Unstable areas. 258.15 Section 258.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Location Restrictions § 258.15 Unstable areas. (a) Owners or operators of new...

40 CFR 258.56 - Assessment of corrective measures.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Assessment of corrective measures. 258.56 Section 258.56 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.56...

40 CFR 258.70 - Applicability and effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Applicability and effective date. 258.70 Section 258.70 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Financial Assurance Criteria § 258.70 Applicability and...

40 CFR 258.70 - Applicability and effective date.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Applicability and effective date. 258.70 Section 258.70 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Financial Assurance Criteria § 258.70 Applicability and...

46 CFR 107.258 - Crane certification.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Crane certification. 107.258 Section 107.258 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION Inspection and Certification § 107.258 Crane certification. (a) The Coast Guard may accept current...

46 CFR 107.258 - Crane certification.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Crane certification. 107.258 Section 107.258 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION Inspection and Certification § 107.258 Crane certification. (a) The Coast Guard may accept current...

46 CFR 107.258 - Crane certification.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Crane certification. 107.258 Section 107.258 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION Inspection and Certification § 107.258 Crane certification. (a) The Coast Guard may accept current...

46 CFR 107.258 - Crane certification.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Crane certification. 107.258 Section 107.258 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION Inspection and Certification § 107.258 Crane certification. (a) The Coast Guard may accept current...

46 CFR 107.258 - Crane certification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Crane certification. 107.258 Section 107.258 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION Inspection and Certification § 107.258 Crane certification. (a) The Coast Guard may accept current...

7 CFR 917.258 - Assessment rate.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 8 2011-01-01 2011-01-01 false Assessment rate. 917.258 Section 917.258 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... CALIFORNIA Assessment Rates § 917.258 Assessment rate. On and after March 1, 2010, an assessment rate of $0...

7 CFR 917.258 - Assessment rate.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Assessment rate. 917.258 Section 917.258 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... CALIFORNIA Assessment Rates § 917.258 Assessment rate. On and after March 1, 2009 an assessment rate of $0...

7 CFR 868.258 - Moisture.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 7 2013-01-01 2013-01-01 false Moisture. 868.258 Section 868.258 Agriculture... Governing Application of Standards § 868.258 Moisture. Water content in brown rice for processing as... purpose of this paragraph, “approved device” shall include the Motomco Moisture Meter and any other...

7 CFR 868.258 - Moisture.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 7 2012-01-01 2012-01-01 false Moisture. 868.258 Section 868.258 Agriculture... Governing Application of Standards § 868.258 Moisture. Water content in brown rice for processing as... purpose of this paragraph, “approved device” shall include the Motomco Moisture Meter and any other...

7 CFR 868.258 - Moisture.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 7 2014-01-01 2014-01-01 false Moisture. 868.258 Section 868.258 Agriculture... Governing Application of Standards § 868.258 Moisture. Water content in brown rice for processing as... purpose of this paragraph, “approved device” shall include the Motomco Moisture Meter and any other...

6 CFR 25.8 - Government contractor Defense.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 6 Domestic Security 1 2012-01-01 2012-01-01 false Government contractor Defense. 25.8 Section 25.8...-TERRORISM BY FOSTERING EFFECTIVE TECHNOLOGIES § 25.8 Government contractor Defense. (a) Criteria for... applicability of the government contractor defense. In determining whether to issue such Certification, the...

6 CFR 25.8 - Government contractor Defense.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 6 Domestic Security 1 2013-01-01 2013-01-01 false Government contractor Defense. 25.8 Section 25.8...-TERRORISM BY FOSTERING EFFECTIVE TECHNOLOGIES § 25.8 Government contractor Defense. (a) Criteria for... applicability of the government contractor defense. In determining whether to issue such Certification, the...

40 CFR 258.57 - Selection of remedy.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 258.57 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.57 Selection of remedy... environment; and (4) Comply with standards for management of wastes as specified in § 258.58(d). (c) In...

40 CFR 258.57 - Selection of remedy.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 258.57 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.57 Selection of remedy... environment; and (4) Comply with standards for management of wastes as specified in § 258.58(d). (c) In...

40 CFR 258.14 - Seismic impact zones.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Seismic impact zones. 258.14 Section 258.14 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Location Restrictions § 258.14 Seismic impact zones. (a) New MSWLF units and...

40 CFR 258.14 - Seismic impact zones.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Seismic impact zones. 258.14 Section 258.14 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Location Restrictions § 258.14 Seismic impact zones. (a) New MSWLF units and...

42 CFR 84.258 - Fees.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Fees. 84.258 Section 84.258 Public Health PUBLIC... RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Special Use Respirators § 84.258 Fees. The following fees shall be charged for the examination, inspection, and testing of complete assemblies and...

6 CFR 25.8 - Government contractor Defense.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 6 Domestic Security 1 2010-01-01 2010-01-01 false Government contractor Defense. 25.8 Section 25.8...-TERRORISM BY FOSTERING EFFECTIVE TECHNOLOGIES § 25.8 Government contractor Defense. (a) Criteria for... applicability of the government contractor defense. In determining whether to issue such Certification, the...

1. Photocopy of undated wash drawing. The largest building is ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Photocopy of undated wash drawing. The largest building is the Hotel Williams. Next to it is the Williams House (Williams Hotel Annex), HABS No. MI-258 A. Below them are the log cabins built by the American Fur Company (from left to right): Log Building No. 1 (MI-258 C), Log Building No. 2 (MI-258 D), Log Building No. 3 (not documented), Log Building No. 4 (MI-258 E), and Log Building No. 5 (MI-258 F). (Williams Log House, MI-258 B, and Log Building No. 8, MI-258 G, are not shown). The drawing is in the collection of the Michigan Historical Commission. Although it does not have a date, it was painted in the early 20th century after the main building was constructed. - Hotel Williams, Murray Bay, Munising, Alger County, MI

38 CFR 3.258-3.259 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false [Reserved] 3.258-3.259 Section 3.258-3.259 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation Dependency, Income and Estate §§ 3.258-3...

38 CFR 3.258-3.259 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false [Reserved] 3.258-3.259 Section 3.258-3.259 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation Dependency, Income and Estate §§ 3.258-3...

38 CFR 3.258-3.259 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false [Reserved] 3.258-3.259 Section 3.258-3.259 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation Dependency, Income and Estate §§ 3.258-3...

38 CFR 3.258-3.259 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 1 2012-07-01 2012-07-01 false [Reserved] 3.258-3.259 Section 3.258-3.259 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation Dependency, Income and Estate §§ 3.258-3...

38 CFR 3.258-3.259 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false [Reserved] 3.258-3.259 Section 3.258-3.259 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation Dependency, Income and Estate §§ 3.258-3...

40 CFR 258.24 - Air criteria.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Air criteria. 258.24 Section 258.24... SOLID WASTE LANDFILLS Operating Criteria § 258.24 Air criteria. (a) Owners or operators of all MSWLFs... Implementation Plan (SIP) approved or promulgated by the Administrator pursuant to section 110 of the Clean Air...

40 CFR 258.24 - Air criteria.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Air criteria. 258.24 Section 258.24... SOLID WASTE LANDFILLS Operating Criteria § 258.24 Air criteria. (a) Owners or operators of all MSWLFs... Implementation Plan (SIP) approved or promulgated by the Administrator pursuant to section 110 of the Clean Air...

40 CFR 258.24 - Air criteria.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Air criteria. 258.24 Section 258.24... SOLID WASTE LANDFILLS Operating Criteria § 258.24 Air criteria. (a) Owners or operators of all MSWLFs... Implementation Plan (SIP) approved or promulgated by the Administrator pursuant to section 110 of the Clean Air...

40 CFR 258.73 - Financial assurance for corrective action.

Code of Federal Regulations, 2011 CFR

2011-07-01

... action. 258.73 Section 258.73 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID... the cost of hiring a third party to perform the corrective action in accordance with the program required under § 258.58 of this part. The corrective action cost estimate must account for the total costs...

40 CFR 258.75 - Discounting.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL... State may allow discounting of closure cost estimates in § 258.71(a), post-closure cost estimates in § 258.72(a), and/or corrective action costs in § 258.73(a) up to the rate of return for essentially risk...

40 CFR 258.73 - Financial assurance for corrective action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... action. 258.73 Section 258.73 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID... the cost of hiring a third party to perform the corrective action in accordance with the program required under § 258.58 of this part. The corrective action cost estimate must account for the total costs...

40 CFR Appendix I to Part 258 - Constituents for Detection Monitoring

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Constituents for Detection Monitoring I Appendix I to Part 258 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Pt. 258, App. I Appendix I to Part 258—Constituents...

40 CFR Appendix I to Part 258 - Constituents for Detection Monitoring

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Constituents for Detection Monitoring I Appendix I to Part 258 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Pt. 258, App. I Appendix I to Part 258—Constituents...

40 CFR 258.3 - Consideration of other Federal laws.

Code of Federal Regulations, 2011 CFR

2011-07-01

.... 258.3 Section 258.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS General § 258.3 Consideration of other Federal laws. The owner or operator of a municipal solid waste landfill unit must comply with any other applicable Federal...

40 CFR 258.3 - Consideration of other Federal laws.

Code of Federal Regulations, 2010 CFR

2010-07-01

.... 258.3 Section 258.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS General § 258.3 Consideration of other Federal laws. The owner or operator of a municipal solid waste landfill unit must comply with any other applicable Federal...

40 CFR 258.27 - Surface water requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Surface water requirements. 258.27 Section 258.27 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.27 Surface water requirements. MSWLF units shall not: (a) Cause a discharge of...

40 CFR 258.51 - Ground-water monitoring systems.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Ground-water monitoring systems. 258.51 Section 258.51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.51 Ground-water monitoring systems. (a) A...

40 CFR 258.72 - Financial assurance for post-closure care.

Code of Federal Regulations, 2011 CFR

2011-07-01

... care. 258.72 Section 258.72 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID... dollars, of the cost of hiring a third party to conduct post-closure care for the MSWLF unit in compliance with the post-closure plan developed under § 258.61 of this part. The post-closure cost estimate used...

40 CFR 258.26 - Run-on/run-off control systems.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Run-on/run-off control systems. 258.26 Section 258.26 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.26 Run-on/run-off control systems. (a...

40 CFR 258.26 - Run-on/run-off control systems.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Run-on/run-off control systems. 258.26 Section 258.26 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.26 Run-on/run-off control systems. (a...

40 CFR 258.20 - Procedures for excluding the receipt of hazardous waste.

Code of Federal Regulations, 2011 CFR

2011-07-01

... of hazardous waste. 258.20 Section 258.20 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.20 Procedures..., regulated hazardous waste means a solid waste that is a hazardous waste, as defined in 40 CFR 261.3, that is...

40 CFR 258.20 - Procedures for excluding the receipt of hazardous waste.

Code of Federal Regulations, 2010 CFR

2010-07-01

... of hazardous waste. 258.20 Section 258.20 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.20 Procedures..., regulated hazardous waste means a solid waste that is a hazardous waste, as defined in 40 CFR 261.3, that is...

40 CFR 258.53 - Ground-water sampling and analysis requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Ground-water sampling and analysis requirements. 258.53 Section 258.53 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.53 Ground-water sampling and analysi...

40 CFR 258.53 - Ground-water sampling and analysis requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Ground-water sampling and analysis requirements. 258.53 Section 258.53 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.53 Ground-water sampling and analysi...

40 CFR 258.10 - Airport safety.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Airport safety. 258.10 Section 258.10... SOLID WASTE LANDFILLS Location Restrictions § 258.10 Airport safety. (a) Owners or operators of new... meters) of any airport runway end used by turbojet aircraft or within 5,000 feet (1,524 meters) of any...

40 CFR 258.10 - Airport safety.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Airport safety. 258.10 Section 258.10... SOLID WASTE LANDFILLS Location Restrictions § 258.10 Airport safety. (a) Owners or operators of new... meters) of any airport runway end used by turbojet aircraft or within 5,000 feet (1,524 meters) of any...

40 CFR 258.10 - Airport safety.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Airport safety. 258.10 Section 258.10... SOLID WASTE LANDFILLS Location Restrictions § 258.10 Airport safety. (a) Owners or operators of new... meters) of any airport runway end used by turbojet aircraft or within 5,000 feet (1,524 meters) of any...

37 CFR 258.3 - Royalty fee for secondary transmission of analog signals of broadcast stations by satellite...

Code of Federal Regulations, 2011 CFR

2011-07-01

... transmission of analog signals of broadcast stations by satellite carriers. 258.3 Section 258.3 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT ARBITRATION ROYALTY PANEL RULES AND PROCEDURES ADJUSTMENT OF ROYALTY FEE FOR SECONDARY TRANSMISSIONS BY SATELLITE CARRIERS § 258.3...

29 CFR 779.258 - Sales made or business done.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Sales made or business done. 779.258 Section 779.258 Labor... Volume of Sales Made Or Business Done § 779.258 Sales made or business done. The Senate Report on the 1966 amendments reaffirmed the intent to measure the “dollar volume of sales or business” including...

47 CFR 1.258 - Closing of the hearing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Closing of the hearing. 1.258 Section 1.258... Intermediate Decision § 1.258 Closing of the hearing. The record of hearing shall be closed by an announcement... concluded. In the discretion of the presiding officer, the record may be closed as of a future specified...

Surveys of current status in biomedical science grant review: funding organisations' and grant reviewers' perspectives

PubMed Central

2010-01-01

Background The objectives of this research were (a) to describe the current status of grant review for biomedical projects and programmes from the perspectives of international funding organisations and grant reviewers, and (b) to explore funders' interest in developing uniform requirements for grant review aimed at making the processes and practices of grant review more consistent, transparent, and user friendly. Methods A survey to a convenience sample of 57 international public and private organisations that give grants for biomedical research was conducted. Nine participating organisations then emailed a random sample of their external reviewers an invitation to participate in a second electronic survey. Results A total of 28 of 57 (49%) organisations in 19 countries responded. Organisations reported these problems as frequent or very frequent: declined review requests (16), late reports (10), administrative burden (7), difficulty finding new reviewers (4), and reviewers not following guidelines (4). The administrative burden of the process was reported to have increased over the past 5 years. In all, 17 organisations supported the idea of uniform requirements for conducting grant review and for formatting grant proposals. A total of 258/418 (62%) reviewers responded from 22 countries. Of those, 48% (123/258) said their institutions encouraged grant review, yet only 7% (17/258) were given protected time and 74% (192/258) received no academic recognition for this. Reviewers rated these factors as extremely or very important in deciding to review proposals: 51% (131/258) desire to support external fairness, 47% (120/258) professional duty, 46% (118/258) relevance of the proposal's topic, 43% (110/258) wanting to keep up to date, 40% (104/258) desire to avoid suppression of innovation. Only 16% (42/258) reported that guidance from funders was very clear. In all, 85% (220/258) had not been trained in grant review and 64% (166/258) wanted this. Conclusions Funders reported a growing workload of biomedical proposals that is getting harder to peer review. Just under half of grant reviewers take part for the good of science and professional development, but many report lack of academic and practical support and clear guidance. Around two-thirds of funders supported the development of uniform requirements for the format and peer review of proposals to help ease the current situation. PMID:20961441

40 CFR 258.29 - Recordkeeping requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Section 258.29 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.29 Recordkeeping requirements. (a) The... of an approved state program may receive electronic documents only if the state program includes the...

40 CFR 258.29 - Recordkeeping requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Section 258.29 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.29 Recordkeeping requirements. (a) The... of an approved state program may receive electronic documents only if the state program includes the...

40 CFR 258.29 - Recordkeeping requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Section 258.29 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.29 Recordkeeping requirements. (a) The... of an approved state program may receive electronic documents only if the state program includes the...

40 CFR 258.11 - Floodplains.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Floodplains. 258.11 Section 258.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL...: (1) Floodplain means the lowland and relatively flat areas adjoining inland and coastal waters...

40 CFR 258.11 - Floodplains.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Floodplains. 258.11 Section 258.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL...: (1) Floodplain means the lowland and relatively flat areas adjoining inland and coastal waters...

40 CFR 258.11 - Floodplains.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Floodplains. 258.11 Section 258.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL...: (1) Floodplain means the lowland and relatively flat areas adjoining inland and coastal waters...

40 CFR 258.11 - Floodplains.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Floodplains. 258.11 Section 258.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL...: (1) Floodplain means the lowland and relatively flat areas adjoining inland and coastal waters...

40 CFR 258.11 - Floodplains.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Floodplains. 258.11 Section 258.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL...: (1) Floodplain means the lowland and relatively flat areas adjoining inland and coastal waters...

37 CFR 258.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Definitions. 258.2 Section 258.2 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT ARBITRATION ROYALTY PANEL RULES AND PROCEDURES ADJUSTMENT OF ROYALTY FEE FOR SECONDARY TRANSMISSIONS BY SATELLITE...

37 CFR 258.1 - General.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT ARBITRATION ROYALTY PANEL RULES AND PROCEDURES ADJUSTMENT OF ROYALTY FEE FOR SECONDARY TRANSMISSIONS BY SATELLITE CARRIERS § 258.1 General. This part 258 adjusts the rates of royalties payable under the compulsory license for...

40 CFR 258.28 - Liquids restrictions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 258.28 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.28 Liquids restrictions. (a) Bulk or... (Paint Filter Liquids Test), included in “Test Methods for Evaluating Solid Waste, Physical/Chemical...

40 CFR 258.28 - Liquids restrictions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 258.28 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.28 Liquids restrictions. (a) Bulk or... (Paint Filter Liquids Test), included in “Test Methods for Evaluating Solid Waste, Physical/Chemical...

40 CFR 258.56 - Assessment of corrective measures.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Assessment of corrective measures. 258.56 Section 258.56 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... implementation, and potential impacts of appropriate potential remedies, including safety impacts, cross-media...

40 CFR 258.25 - Access requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... wastes by using artificial barriers, natural barriers, or both, as appropriate to protect human health... 258.25 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.25 Access requirements. Owners or operators of all...

40 CFR 258.25 - Access requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... wastes by using artificial barriers, natural barriers, or both, as appropriate to protect human health... 258.25 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.25 Access requirements. Owners or operators of all...

40 CFR 258.25 - Access requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 258.25 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.25 Access requirements. Owners or operators of all... wastes by using artificial barriers, natural barriers, or both, as appropriate to protect human health...

40 CFR 258.25 - Access requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 258.25 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.25 Access requirements. Owners or operators of all... wastes by using artificial barriers, natural barriers, or both, as appropriate to protect human health...

14 CFR 258.1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Purpose. 258.1 Section 258.1 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC... consumers are adequately informed before they book air transportation or embark on travel involving change...

14 CFR 258.1 - Purpose.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Purpose. 258.1 Section 258.1 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC... consumers are adequately informed before they book air transportation or embark on travel involving change...

14 CFR 258.1 - Purpose.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Purpose. 258.1 Section 258.1 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC... consumers are adequately informed before they book air transportation or embark on travel involving change...

14 CFR 258.1 - Purpose.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Purpose. 258.1 Section 258.1 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC... consumers are adequately informed before they book air transportation or embark on travel involving change...

14 CFR 258.1 - Purpose.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Purpose. 258.1 Section 258.1 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC... consumers are adequately informed before they book air transportation or embark on travel involving change...

37 CFR 258.1 - General.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false General. 258.1 Section 258.1 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT ARBITRATION ROYALTY PANEL RULES AND PROCEDURES ADJUSTMENT OF ROYALTY FEE FOR SECONDARY TRANSMISSIONS BY SATELLITE CARRIERS...

Antimicrobial activity and mechanism of action of a novel cationic α-helical octadecapeptide derived from heat shock protein 70 of rice.

PubMed

Taniguchi, Masayuki; Ikeda, Atsuo; Nakamichi, Shun-Ichi; Ishiyama, Yohei; Saitoh, Eiichi; Kato, Tetsuo; Ochiai, Akihito; Tanaka, Takaaki

2013-10-01

Hsp70(241-258), an octadecapeptide derived from the heat shock protein 70 (Hsp70) of rice (Oryza sativa L. japonica), is a novel cationic α-helical antimicrobial peptide (AMP) that contains four lysine, two arginine, and two histidine residues. The antimicrobial activity of Hsp70(241-258) against Porphyromonas gingivalis, a periodontal pathogen, and Candida albicans, an opportunistic fungal pathogen, was quantitatively evaluated using a chemiluminescence method that measures ATP derived from viable cells. The 50% growth-inhibitory concentrations of Hsp70(241-258) against P. gingivalis and C. albicans cells were 63 μM and 70 μM, respectively. Hsp70(241-258) had little or no hemolytic activity even at 1mM, and showed negligible cytotoxicity up to 300 μM. The degrees of calcein leakage from large unilamellar vesicles, which mimic the membranes of Gram-negative bacteria, and 3,3'-dipropylthiadicarbocyanine iodide release from P. gingivalis cells induced by the addition of Hsp70(241-258) increased in a concentration-dependent manner. When Hsp70(241-258) was added to calcein-acetoxymethyl ester-loaded C. albicans cells, calcein release from the cells increased in a concentration-dependent manner. Flow cytometric analysis also showed that the percentages of C. albicans cells stained with propidium iodide, a DNA-intercalating dye, increased as the concentration of Hsp70(241-258) added was increased. Therefore, Hsp70(241-258) appears to exhibit antimicrobial activity against P. gingivalis and C. albicans through membrane disruption. These results suggest that Hsp70(241-258) could be useful as a safe and potent AMP against P. gingivalis and C. albicans in many fields of health care, especially in the control of oral infections. Copyright © 2013 Elsevier Inc. All rights reserved.

40 CFR 25.8 - Responsiveness summaries.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Responsiveness summaries. 25.8 Section 25.8 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PUBLIC PARTICIPATION IN PROGRAMS UNDER THE RESOURCE CONSERVATION AND RECOVERY ACT, THE SAFE DRINKING WATER ACT, AND THE CLEAN WATER...

40 CFR 258.12 - Wetlands.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Wetlands. 258.12 Section 258.12... Act or applicable State wetlands laws, the presumption that practicable alternative to the proposed... Species Act of 1973, and (iv) Violate any requirement under the Marine Protection, Research, and...

40 CFR 258.12 - Wetlands.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Wetlands. 258.12 Section 258.12... Act or applicable State wetlands laws, the presumption that practicable alternative to the proposed... Species Act of 1973, and (iv) Violate any requirement under the Marine Protection, Research, and...

40 CFR 258.12 - Wetlands.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Wetlands. 258.12 Section 258.12... Act or applicable State wetlands laws, the presumption that practicable alternative to the proposed... Species Act of 1973, and (iv) Violate any requirement under the Marine Protection, Research, and...

47 CFR 73.258 - Indicating instruments.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false Indicating instruments. 73.258 Section 73.258 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO BROADCAST SERVICES FM....3549 may be filed with the FCC, Attention: Audio Division, Media Bureau, in Washington, DC for such...

40 CFR 258.21 - Cover material requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Section 258.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.21 Cover material requirements. (a... cover disposed solid waste with six inches of earthen material at the end of each operating day, or at...

40 CFR 258.55 - Assessment monitoring program.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Section 258.55 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.55 Assessment... be shown that the removed constituents are not reasonably expected to be in or derived from the waste...

40 CFR 258.21 - Cover material requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Section 258.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.21 Cover material requirements. (a... cover disposed solid waste with six inches of earthen material at the end of each operating day, or at...

TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation.

PubMed

Graham, Daniel B; Lefkovith, Ariel; Deelen, Patrick; de Klein, Niek; Varma, Mukund; Boroughs, Angela; Desch, A Nicole; Ng, Aylwin C Y; Guzman, Gaelen; Schenone, Monica; Petersen, Christine P; Bhan, Atul K; Rivas, Manuel A; Daly, Mark J; Carr, Steven A; Wijmenga, Cisca; Xavier, Ramnik J

2016-12-13

Significant insights into disease pathogenesis have been gleaned from population-level genetic studies; however, many loci associated with complex genetic disease contain numerous genes, and phenotypic associations cannot be assigned unequivocally. In particular, a gene-dense locus on chromosome 11 (61.5-61.65 Mb) has been associated with inflammatory bowel disease, rheumatoid arthritis, and coronary artery disease. Here, we identify TMEM258 within this locus as a central regulator of intestinal inflammation. Strikingly, Tmem258 haploinsufficient mice exhibit severe intestinal inflammation in a model of colitis. At the mechanistic level, we demonstrate that TMEM258 is a required component of the oligosaccharyltransferase complex and is essential for N-linked protein glycosylation. Consequently, homozygous deficiency of Tmem258 in colonic organoids results in unresolved endoplasmic reticulum (ER) stress culminating in apoptosis. Collectively, our results demonstrate that TMEM258 is a central mediator of ER quality control and intestinal homeostasis. Copyright © 2016 The Author(s). Published by Elsevier Inc. All rights reserved.

20 CFR 258.2 - Witnesses.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Witnesses. 258.2 Section 258.2 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT HEARINGS BEFORE THE BOARD... a delegation of authority to such examiner to require and compel the attendance of witnesses and the...

40 CFR 258.27 - Surface water requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Surface water requirements. 258.27... FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.27 Surface water requirements. MSWLF... wetlands, that violates any requirements of the Clean Water Act, including, but not limited to, the...

40 CFR 258.27 - Surface water requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Surface water requirements. 258.27... FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.27 Surface water requirements. MSWLF... wetlands, that violates any requirements of the Clean Water Act, including, but not limited to, the...

40 CFR 258.55 - Assessment monitoring program.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Assessment monitoring program. 258.55 Section 258.55 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA... days; or (2) May demonstrate that a source other than a MSWLF unit caused the contamination, or that...

40 CFR 258.1 - Purpose, scope, and applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

....1 Section 258.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS General § 258.1 Purpose, scope, and applicability. (a) The... Recovery Act (RCRA or the Act), as amended, for all municipal solid waste landfill (MSWLF) units and under...

40 CFR 258.23 - Explosive gases control.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Section 258.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.23 Explosive gases control. (a) Owners or... of MSWLFs that dispose of 20 tons of municipal solid waste per day or less, based on an annual...

40 CFR 258.1 - Purpose, scope, and applicability.

Code of Federal Regulations, 2011 CFR

2011-07-01

....1 Section 258.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS General § 258.1 Purpose, scope, and applicability. (a) The... Recovery Act (RCRA or the Act), as amended, for all municipal solid waste landfill (MSWLF) units and under...

40 CFR 258.23 - Explosive gases control.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Section 258.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.23 Explosive gases control. (a) Owners or... of MSWLFs that dispose of 20 tons of municipal solid waste per day or less, based on an annual...

40 CFR 258.27 - Surface water requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Surface water requirements. 258.27... FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.27 Surface water requirements. MSWLF... wetlands, that violates any requirements of the Clean Water Act, including, but not limited to, the...

Evolution of developmental roles of Pax2/5/8 paralogs after independent duplication in urochordate and vertebrate lineages.

PubMed

Bassham, Susan; Cañestro, Cristian; Postlethwait, John H

2008-08-22

Gene duplication provides opportunities for lineage diversification and evolution of developmental novelties. Duplicated genes generally either disappear by accumulation of mutations (nonfunctionalization), or are preserved either by the origin of positively selected functions in one or both duplicates (neofunctionalization), or by the partitioning of original gene subfunctions between the duplicates (subfunctionalization). The Pax2/5/8 family of important developmental regulators has undergone parallel expansion among chordate groups. After the divergence of urochordate and vertebrate lineages, two rounds of independent gene duplications resulted in the Pax2, Pax5, and Pax8 genes of most vertebrates (the sister group of the urochordates), and an additional duplication provided the pax2a and pax2b duplicates in teleost fish. Separate from the vertebrate genome expansions, a duplication also created two Pax2/5/8 genes in the common ancestor of ascidian and larvacean urochordates. To better understand mechanisms underlying the evolution of duplicated genes, we investigated, in the larvacean urochordate Oikopleura dioica, the embryonic gene expression patterns of Pax2/5/8 paralogs. We compared the larvacean and ascidian expression patterns to infer modular subfunctions present in the single pre-duplication Pax2/5/8 gene of stem urochordates, and we compared vertebrate and urochordate expression to infer the suite of Pax2/5/8 gene subfunctions in the common ancestor of olfactores (vertebrates + urochordates). Expression pattern differences of larvacean and ascidian Pax2/5/8 orthologs in the endostyle, pharynx and hindgut suggest that some ancestral gene functions have been partitioned differently to the duplicates in the two urochordate lineages. Novel expression in the larvacean heart may have resulted from the neofunctionalization of a Pax2/5/8 gene in the urochordates. Expression of larvacean Pax2/5/8 in the endostyle, in sites of epithelial remodeling, and in sensory tissues evokes like functions of Pax2, Pax5 and Pax8 in vertebrate embryos, and may indicate ancient origins for these functions in the chordate common ancestor. Comparative analysis of expression patterns of chordate Pax2/5/8 duplicates, rooted on the single-copy Pax2/5/8 gene of amphioxus, whose lineage diverged basally among chordates, provides new insights into the evolution and development of the heart, thyroid, pharynx, stomodeum and placodes in chordates; supports the controversial conclusion that the atrial siphon of ascidians and the otic placode in vertebrates are homologous; and backs the notion that Pax2/5/8 functioned in ancestral chordates to engineer epithelial fusions and perforations, including gill slit openings.

40 CFR 258.22 - Disease vector control.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Disease vector control. 258.22 Section... MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.22 Disease vector control. (a) Owners or operators of all MSWLF units must prevent or control on-site populations of disease vectors using techniques...

40 CFR 258.22 - Disease vector control.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Disease vector control. 258.22 Section... MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.22 Disease vector control. (a) Owners or operators of all MSWLF units must prevent or control on-site populations of disease vectors using techniques...

40 CFR 258.22 - Disease vector control.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Disease vector control. 258.22 Section... MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.22 Disease vector control. (a) Owners or operators of all MSWLF units must prevent or control on-site populations of disease vectors using techniques...

40 CFR 258.22 - Disease vector control.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Disease vector control. 258.22 Section... MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.22 Disease vector control. (a) Owners or operators of all MSWLF units must prevent or control on-site populations of disease vectors using techniques...

40 CFR 258.22 - Disease vector control.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Disease vector control. 258.22 Section... MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.22 Disease vector control. (a) Owners or operators of all MSWLF units must prevent or control on-site populations of disease vectors using techniques...

40 CFR 258.23 - Explosive gases control.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Explosive gases control. 258.23... FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.23 Explosive gases control. (a) Owners or... facility does not exceed 25 percent of the lower explosive limit for methane in facility structures...

40 CFR 258.23 - Explosive gases control.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Explosive gases control. 258.23... FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.23 Explosive gases control. (a) Owners or... facility does not exceed 25 percent of the lower explosive limit for methane in facility structures...

40 CFR 258.23 - Explosive gases control.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Explosive gases control. 258.23 Section... MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.23 Explosive gases control. (a) Owners or operators... does not exceed 25 percent of the lower explosive limit for methane in facility structures (excluding...

40 CFR 258.75 - Discounting.

Code of Federal Regulations, 2010 CFR

2010-07-01

... § 258.72(a), and/or corrective action costs in § 258.73(a) up to the rate of return for essentially risk free investments, net of inflation, under the following conditions: (a) The State Director determines... estimate of site life; and (d) Discounted cost estimates must be adjusted annually to reflect inflation and...

40 CFR 258.51 - Ground-water monitoring systems.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Ground-water monitoring systems. 258... CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.51 Ground-water monitoring systems. (a) A ground-water monitoring system must be installed that consists of a...

40 CFR 258.51 - Ground-water monitoring systems.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Ground-water monitoring systems. 258.51... FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.51 Ground-water monitoring systems. (a) A ground-water monitoring system must be installed that consists of a...

40 CFR 258.58 - Implementation of the corrective action program.

Code of Federal Regulations, 2012 CFR

2012-07-01

... WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258... implement a corrective action ground-water monitoring program that: (i) At a minimum, meet the requirements of an assessment monitoring program under § 258.55; (ii) Indicate the effectiveness of the corrective...

40 CFR 258.51 - Ground-water monitoring systems.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Ground-water monitoring systems. 258... CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.51 Ground-water monitoring systems. (a) A ground-water monitoring system must be installed that consists of a...

40 CFR 258.57 - Selection of remedy.

Code of Federal Regulations, 2014 CFR

2014-07-01

...-water quantity and quality; (iv) The potential damage to wildlife, crops, vegetation, and physical... MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.57 Selection of remedy... environment; (2) Attain the ground-water protection standard as specified pursuant to §§ 258.55 (h) or (i); (3...

40 CFR 258.57 - Selection of remedy.

Code of Federal Regulations, 2013 CFR

2013-07-01

...-water quantity and quality; (iv) The potential damage to wildlife, crops, vegetation, and physical... MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.57 Selection of remedy... environment; (2) Attain the ground-water protection standard as specified pursuant to §§ 258.55 (h) or (i); (3...

40 CFR 258.57 - Selection of remedy.

Code of Federal Regulations, 2012 CFR

2012-07-01

...-water quantity and quality; (iv) The potential damage to wildlife, crops, vegetation, and physical... MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.57 Selection of remedy... environment; (2) Attain the ground-water protection standard as specified pursuant to §§ 258.55 (h) or (i); (3...

Epidemic potential of Escherichia coli ST131 and Klebsiella pneumoniae ST258: a systematic review and meta-analysis

PubMed Central

Dautzenberg, M J D; Haverkate, M R; Bonten, M J M; Bootsma, M C J

2016-01-01

Objectives Observational studies have suggested that Escherichia coli sequence type (ST) 131 and Klebsiella pneumoniae ST258 have hyperendemic properties. This would be obvious from continuously high incidence and/or prevalence of carriage or infection with these bacteria in specific patient populations. Hyperendemicity could result from increased transmissibility, longer duration of infectiousness, and/or higher pathogenic potential as compared with other lineages of the same species. The aim of our research is to quantitatively estimate these critical parameters for E. coli ST131 and K. pneumoniae ST258, in order to investigate whether E. coli ST131 and K. pneumoniae ST258 are truly hyperendemic clones. Primary outcome measures A systematic literature search was performed to assess the evidence of transmissibility, duration of infectiousness, and pathogenicity for E. coli ST131 and K. pneumoniae ST258. Meta-regression was performed to quantify these characteristics. Results The systematic literature search yielded 639 articles, of which 19 data sources provided information on transmissibility (E. coli ST131 n=9; K. pneumoniae ST258 n=10)), 2 on duration of infectiousness (E. coli ST131 n=2), and 324 on pathogenicity (E. coli ST131 n=285; K. pneumoniae ST258 n=39). Available data on duration of carriage and on transmissibility were insufficient for quantitative assessment. In multivariable meta-regression E. coli isolates causing infection were associated with ST131, compared to isolates only causing colonisation, suggesting that E. coli ST131 can be considered more pathogenic than non-ST131 isolates. Date of isolation, location and resistance mechanism also influenced the prevalence of ST131. E. coli ST131 was 3.2 (95% CI 2.0 to 5.0) times more pathogenic than non-ST131. For K. pneumoniae ST258 there were not enough data for meta-regression assessing the influence of colonisation versus infection on ST258 prevalence. Conclusions With the currently available data, it cannot be confirmed nor rejected, that E. coli ST131 or K. pneumoniae ST258 are hyperendemic clones. PMID:26988349

42 CFR 441.258 - Consent form requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false Consent form requirements. 441.258 Section 441.258... informed consent as set forth on the consent form; and (iii) To the best of his or her knowledge and belief...) To the best of his or her knowledge and belief, the individual appeared mentally competent and...

27 CFR 44.258 - To officers of the armed forces for subsequent exportation.

Code of Federal Regulations, 2010 CFR

2010-04-01

... forces for subsequent exportation. 44.258 Section 44.258 Alcohol, Tobacco Products and Firearms ALCOHOL... forces for subsequent exportation. Where cigars are withdrawn from a customs warehouse for delivery to officers of the armed forces of the United States in this country for subsequent shipment to, and use by...

27 CFR 44.258 - To officers of the armed forces for subsequent exportation.

Code of Federal Regulations, 2011 CFR

2011-04-01

... forces for subsequent exportation. 44.258 Section 44.258 Alcohol, Tobacco Products and Firearms ALCOHOL... forces for subsequent exportation. Where cigars are withdrawn from a customs warehouse for delivery to officers of the armed forces of the United States in this country for subsequent shipment to, and use by...

40 CFR 258.72 - Financial assurance for post-closure care.

Code of Federal Regulations, 2010 CFR

2010-07-01

... care. 258.72 Section 258.72 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID... assurance for post-closure care. (a) The owner or operator must have a detailed written estimate, in current dollars, of the cost of hiring a third party to conduct post-closure care for the MSWLF unit in compliance...

37 CFR 258.4 - Royalty fee for secondary transmission of digital signals of broadcast stations by satellite...

Code of Federal Regulations, 2012 CFR

2012-07-01

... transmission of digital signals of broadcast stations by satellite carriers. 258.4 Section 258.4 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT ARBITRATION ROYALTY PANEL RULES... Royalty fee for secondary transmission of digital signals of broadcast stations by satellite carriers. (a...

37 CFR 258.4 - Royalty fee for secondary transmission of digital signals of broadcast stations by satellite...

Code of Federal Regulations, 2013 CFR

2013-07-01

... transmission of digital signals of broadcast stations by satellite carriers. 258.4 Section 258.4 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT ARBITRATION ROYALTY PANEL RULES... Royalty fee for secondary transmission of digital signals of broadcast stations by satellite carriers. (a...

37 CFR 258.4 - Royalty fee for secondary transmission of digital signals of broadcast stations by satellite...

Code of Federal Regulations, 2011 CFR

2011-07-01

... transmission of digital signals of broadcast stations by satellite carriers. 258.4 Section 258.4 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT ARBITRATION ROYALTY PANEL RULES... Royalty fee for secondary transmission of digital signals of broadcast stations by satellite carriers. (a...

37 CFR 258.4 - Royalty fee for secondary transmission of digital signals of broadcast stations by satellite...

Code of Federal Regulations, 2014 CFR

2014-07-01

... transmission of digital signals of broadcast stations by satellite carriers. 258.4 Section 258.4 Patents, Trademarks, and Copyrights U.S. COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT ARBITRATION ROYALTY PANEL... Royalty fee for secondary transmission of digital signals of broadcast stations by satellite carriers. (a...

37 CFR 258.4 - Royalty fee for secondary transmission of digital signals of broadcast stations by satellite...

Code of Federal Regulations, 2010 CFR

2010-07-01

... transmission of digital signals of broadcast stations by satellite carriers. 258.4 Section 258.4 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT ARBITRATION ROYALTY PANEL RULES... Royalty fee for secondary transmission of digital signals of broadcast stations by satellite carriers. (a...

The −258 A/G (SNP rs12885300) polymorphism of the human type-2 deiodinase gene is associated with a shift in the pattern of secretion of thyroid hormones following a TRH-induced acute rise in TSH

PubMed Central

Peltsverger, Maya Y.; Butler, Peter W.; Alberobello, Anna Teresa; Smith, Sheila; Guevara, Yanina; Dubaz, Ornella M.; Luzon, Javier A.; Linderman, Joyce; Celi, Francesco S.

2012-01-01

Objective Type-2 deiodinase gene (DIO2) polymorphisms have been associated with changes in pituitary-thyroid axis homeostasis. The −258 A/G (SNP rs12885300) polymorphism has been associated with increased enzymatic activity, but data are conflicting. To characterize the effects of the −258 A/G polymorphism on intra-thyroidal T4 to T3 conversion and thyroid hormone secretion pattern we studied the effects of acute, TRH-mediated, TSH stimulation of the thyroid gland. Design Retrospective analysis. Methods The thyroid hormone secretion in response to 500 mcg iv TRH injection was studied in 45 healthy volunteers. Results Twenty-six subjects (16 females, 10 males, 32.8±10.4 years) were homozygous for the ancestral (−258 A/A) allele, 19 (11 females, 8 males, 31.1±10.9 years) were carrier of the (−258 G/x) variant. While no differences in the peak TSH and T3 levels were observed, carriers of the −258G/x allele showed a blunted rise in free T4 (p<0.01). The −258G/x 92Thr/Thr haplotype, compared to the other groups, had lower TSH values at 60' (p<0.03). No differences were observed between genotypes in baseline thyroid hormone levels. Conclusions The −258G/x DIO2 polymorphism variant is associated with a decreased rate of acute TSH-stimulated free T4 secretion with a normal T3 release from the thyroid consistent with a shift in the reaction equilibrium toward the product. These data indicate that the −258G DIO2 polymorphism cause changes in the pattern of hormonal secretion. These findings are a proof-of-concept that common polymorphisms in the DIO2 can subtly affect the circulating levels of thyroid hormone and might modulate the thyroid hormone homeostasis. PMID:22307573

Evolution of developmental roles of Pax2/5/8 paralogs after independent duplication in urochordate and vertebrate lineages

PubMed Central

Bassham, Susan; Cañestro, Cristian; Postlethwait, John H

2008-01-01

Background Gene duplication provides opportunities for lineage diversification and evolution of developmental novelties. Duplicated genes generally either disappear by accumulation of mutations (nonfunctionalization), or are preserved either by the origin of positively selected functions in one or both duplicates (neofunctionalization), or by the partitioning of original gene subfunctions between the duplicates (subfunctionalization). The Pax2/5/8 family of important developmental regulators has undergone parallel expansion among chordate groups. After the divergence of urochordate and vertebrate lineages, two rounds of independent gene duplications resulted in the Pax2, Pax5, and Pax8 genes of most vertebrates (the sister group of the urochordates), and an additional duplication provided the pax2a and pax2b duplicates in teleost fish. Separate from the vertebrate genome expansions, a duplication also created two Pax2/5/8 genes in the common ancestor of ascidian and larvacean urochordates. Results To better understand mechanisms underlying the evolution of duplicated genes, we investigated, in the larvacean urochordate Oikopleura dioica, the embryonic gene expression patterns of Pax2/5/8 paralogs. We compared the larvacean and ascidian expression patterns to infer modular subfunctions present in the single pre-duplication Pax2/5/8 gene of stem urochordates, and we compared vertebrate and urochordate expression to infer the suite of Pax2/5/8 gene subfunctions in the common ancestor of olfactores (vertebrates + urochordates). Expression pattern differences of larvacean and ascidian Pax2/5/8 orthologs in the endostyle, pharynx and hindgut suggest that some ancestral gene functions have been partitioned differently to the duplicates in the two urochordate lineages. Novel expression in the larvacean heart may have resulted from the neofunctionalization of a Pax2/5/8 gene in the urochordates. Expression of larvacean Pax2/5/8 in the endostyle, in sites of epithelial remodeling, and in sensory tissues evokes like functions of Pax2, Pax5 and Pax8 in vertebrate embryos, and may indicate ancient origins for these functions in the chordate common ancestor. Conclusion Comparative analysis of expression patterns of chordate Pax2/5/8 duplicates, rooted on the single-copy Pax2/5/8 gene of amphioxus, whose lineage diverged basally among chordates, provides new insights into the evolution and development of the heart, thyroid, pharynx, stomodeum and placodes in chordates; supports the controversial conclusion that the atrial siphon of ascidians and the otic placode in vertebrates are homologous; and backs the notion that Pax2/5/8 functioned in ancestral chordates to engineer epithelial fusions and perforations, including gill slit openings. PMID:18721460

40 CFR 258.62 - Approval of site-specific flexibility requests in Indian country.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Closure and Post-Closure Care § 258.62... waste landfill owned and operated by Lake County on the Confederated Salish and Kootenai Tribes... equivalent reduction in infiltration as the infiltration layer specified in § 258.60(a)(1) and (a)(2), and...

30 CFR 250.258 - What information on the onshore support facilities you will use must accompany the DPP or DOCD?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What information on the onshore support facilities you will use must accompany the DPP or DOCD? 250.258 Section 250.258 Mineral Resources BUREAU OF... AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Plans and Information Contents of Development...

30 CFR 250.258 - What information on the onshore support facilities you will use must accompany the DPP or DOCD?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What information on the onshore support facilities you will use must accompany the DPP or DOCD? 250.258 Section 250.258 Mineral Resources MINERALS... CONTINENTAL SHELF Plans and Information Contents of Development and Production Plans (dpp) and Development...

Approximating the r-Process on Earth with Thermonuclear Explosions. Lessons Learned and Unanswered Questions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Becker, Stephen Allan

2016-01-28

During the astrophysical r-process, multiple neutron captures occur so rapidly on target nuclei that their daughter nuclei generally do not have time to undergo radioactive decay before another neutron is captured. The r-process can be approximately simulated on Earth in certain types of thermonuclear explosions through an analogous process of rapid neutron captures known as the "prompt capture" process. Between 1952 and 1969, 23 nuclear tests were fielded by the US which were involved (at least partially) with the "prompt capture" process. Of these tests, 15 were at least partially successful. Some of these tests were conducted under the Plowsharemore » Peaceful Nuclear Explosion Program as scientific research experiments. It is now known that the USSR conducted similar nuclear tests during 1966 to 1979. The elements einsteinium and fermium were first discovered by this process. The most successful tests achieved 19 successive neutron captures on the initial target nuclei. A review of the US program, target nuclei used, heavy element yields, scientific achievements of the program, and how some of the results have been used by the astrophysical community is given. Finally, some unanswered questions concerning very neutron-rich nuclei that could potentially have been answered with additional nuclear experiments is presented.« less

Echolocation-Based Foraging by Harbor Porpoises and Sperm Whales, Including Effects on Noise and Acoustic Propagation

DTIC Science & Technology

2008-09-01

Behavioural Point Process Data 234 Appendix B: Matlab Code 258 Matlab Code Used in Chapter 2 (Porpoise Prey Capture Analysis) 258 Click Extraction and...Measurement of Click Properties 258 Envelope-based Click Detector 262 Matlab Code Used in Chapter 3 (Transmission Loss in Porpoise Habitats) ..267...Click Extraction from Data Wavefiles 267 Click Level Determination (Grand Manan Datasets) 270 Click Level Determination (Danish Datasets) 287 Matlab

7 CFR 868.258 - Moisture.

Code of Federal Regulations, 2011 CFR

2011-01-01

... FOR CERTAIN AGRICULTURAL COMMODITIES United States Standards for Brown Rice for Processing Principles Governing Application of Standards § 868.258 Moisture. Water content in brown rice for processing as...

36 CFR 6.3 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Waste Landfills at 40 CFR 258.60 and 258.61. Compostible materials means organic substances that decay... water, air, soils, geological features, including subsurface strata, the natural processes and...

36 CFR 6.3 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Waste Landfills at 40 CFR 258.60 and 258.61. Compostible materials means organic substances that decay... water, air, soils, geological features, including subsurface strata, the natural processes and...

36 CFR 6.3 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Waste Landfills at 40 CFR 258.60 and 258.61. Compostible materials means organic substances that decay... water, air, soils, geological features, including subsurface strata, the natural processes and...

Regulation of the Incorporation of Tissue Factor into Microparticles by Serine Phosphorylation of the Cytoplasmic Domain of Tissue Factor*

PubMed Central

Collier, Mary E. W.; Ettelaie, Camille

2011-01-01

The mechanisms that regulate the incorporation and release of tissue factors (TFs) into cell-derived microparticles are as yet unidentified. In this study, we have explored the regulation of TF release into microparticles by the phosphorylation of serine residues within the cytoplasmic domain of TF. Wild-type and mutant forms of TF, containing alanine and aspartate substitutions at Ser253 and Ser258, were overexpressed in coronary artery and dermal microvascular endothelial cells and microparticle release stimulated with PAR2 agonist peptide (PAR2-AP). The release of TF antigen and activity was then monitored. In addition, the phosphorylation state of the two serine residues within the released microparticles and the cells was monitored for 150 min. The release of wild-type TF as procoagulant microparticles peaked at 90 min and declined thereafter in both cell types. The TF within these microparticles was phosphorylated at Ser253 but not at Ser258. Aspartate substitution of Ser253 resulted in rapid release of TF antigen but not activity, whereas TF release was reduced and delayed by alanine substitution of Ser253 or aspartate substitution of Ser258. Alanine substitution of Ser258 prolonged the release of TF following PAR2-AP activation. The release of TF was concurrent with phosphorylation of Ser253 and was followed by dephosphorylation at 120 min and phosphorylation of Ser258. We propose a sequential mechanism in which the phosphorylation of Ser253 through PAR2 activation results in the incorporation of TF into microparticles, simultaneously inducing Ser258 phosphorylation. Phosphorylation of Ser258 in turn promotes the dephosphorylation of Ser253 and suppresses the release of TF. PMID:21310953

Vascular disease-causing mutation R258C in ACTA2 disrupts actin dynamics and interaction with myosin

PubMed Central

Lu, Hailong; Fagnant, Patricia M.; Bookwalter, Carol S.; Joel, Peteranne; Trybus, Kathleen M.

2015-01-01

Point mutations in vascular smooth muscle α-actin (SM α-actin), encoded by the gene ACTA2, are the most prevalent cause of familial thoracic aortic aneurysms and dissections (TAAD). Here, we provide the first molecular characterization, to our knowledge, of the effect of the R258C mutation in SM α-actin, expressed with the baculovirus system. Smooth muscles are unique in that force generation requires both interaction of stable actin filaments with myosin and polymerization of actin in the subcortical region. Both aspects of R258C function therefore need investigation. Total internal reflection fluorescence (TIRF) microscopy was used to quantify the growth of single actin filaments as a function of time. R258C filaments are less stable than WT and more susceptible to severing by cofilin. Smooth muscle tropomyosin offers little protection from cofilin cleavage, unlike its effect on WT actin. Unexpectedly, profilin binds tighter to the R258C monomer, which will increase the pool of globular actin (G-actin). In an in vitro motility assay, smooth muscle myosin moves R258C filaments more slowly than WT, and the slowing is exacerbated by smooth muscle tropomyosin. Under loaded conditions, small ensembles of myosin are unable to produce force on R258C actin-tropomyosin filaments, suggesting that tropomyosin occupies an inhibitory position on actin. Many of the observed defects cannot be explained by a direct interaction with the mutated residue, and thus the mutation allosterically affects multiple regions of the monomer. Our results align with the hypothesis that defective contractile function contributes to the pathogenesis of TAAD. PMID:26153420

7 CFR 868.258 - Moisture.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Governing Application of Standards § 868.258 Moisture. Water content in brown rice for processing as... purpose of this paragraph, “approved device” shall include the Motomco Moisture Meter and any other...

40 CFR 258.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

...; stone, glass, clay, and concrete products; textile manufacturing; transportation equipment; and water... the MSWLF unit meets the conditions of § 258.1(f)(1). Open burning means the combustion of solid waste...

40 CFR 258.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

...; stone, glass, clay, and concrete products; textile manufacturing; transportation equipment; and water... the MSWLF unit meets the conditions of § 258.1(f)(1). Open burning means the combustion of solid waste...

40 CFR 258.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

...; stone, glass, clay, and concrete products; textile manufacturing; transportation equipment; and water... the MSWLF unit meets the conditions of § 258.1(f)(1). Open burning means the combustion of solid waste...

E258K HCM-causing mutation in cardiac MyBP-C reduces contractile force and accelerates twitch kinetics by disrupting the cMyBP-C and myosin S2 interaction.

PubMed

De Lange, Willem J; Grimes, Adrian C; Hegge, Laura F; Spring, Alexander M; Brost, Taylor M; Ralphe, J Carter

2013-09-01

Mutations in cardiac myosin binding protein C (cMyBP-C) are prevalent causes of hypertrophic cardiomyopathy (HCM). Although HCM-causing truncation mutations in cMyBP-C are well studied, the growing number of disease-related cMyBP-C missense mutations remain poorly understood. Our objective was to define the primary contractile effect and molecular disease mechanisms of the prevalent cMyBP-C E258K HCM-causing mutation in nonremodeled murine engineered cardiac tissue (mECT). Wild-type and human E258K cMyBP-C were expressed in mECT lacking endogenous mouse cMyBP-C through adenoviral-mediated gene transfer. Expression of E258K cMyBP-C did not affect cardiac cell survival and was appropriately incorporated into the cardiac sarcomere. Functionally, expression of E258K cMyBP-C caused accelerated contractile kinetics and severely compromised twitch force amplitude in mECT. Yeast two-hybrid analysis revealed that E258K cMyBP-C abolished interaction between the N terminal of cMyBP-C and myosin heavy chain sub-fragment 2 (S2). Furthermore, this mutation increased the affinity between the N terminal of cMyBP-C and actin. Assessment of phosphorylation of three serine residues in cMyBP-C showed that aberrant phosphorylation of cMyBP-C is unlikely to be responsible for altering these interactions. We show that the E258K mutation in cMyBP-C abolishes interaction between N-terminal cMyBP-C and myosin S2 by directly disrupting the cMyBP-C-S2 interface, independent of cMyBP-C phosphorylation. Similar to cMyBP-C ablation or phosphorylation, abolition of this inhibitory interaction accelerates contractile kinetics. Additionally, the E258K mutation impaired force production of mECT, which suggests that in addition to the loss of physiological function, this mutation disrupts contractility possibly by tethering the thick and thin filament or acting as an internal load.

RCRA, superfund and EPCRA hotline training module. Introduction to: Municipal solid waste disposal facility criteria updated July 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-07-01

The module provides a summary of the regulatory criteria for municipal solid waste landfills (MSWLFs) and provides the statutory authority under RCRA and the Clean Water Act (CWA) directing EPA to develop the MSWLF criteria in 40 CFR Part 258. It gives the part 258 effective date and the compliance dates for providing demonstrations to satisfy individual regulatory requirements. It identifies the types of facilities that qualify for the small landfill exemption. It explains the requirements of each subpart of part 258 as they apply to states with EPA-approved MSWLF permit programs and states without approved permit programs. It comparesmore » the MSWLF environmental performance standards described in part 258 to the corresponding requirements for hazardous waste TSDFs in part 264, which are generally more stringent.« less

Outcome, Cost, and Oversight of Iraq Reconstruction Contract W914NS-04-D-0006

DTIC Science & Technology

2008-01-28

Minerals HQs Building $7,928,993 2% 03 Modernize Maternity & Pediatric Hospital – Ibn Al Baladi $8,814,353 3% 04 Ministry of Health – Healthcare...Ministerial buildings 8,257,981 8,258,377 Completed Terminated for Convenience 3 Renovate Ibn Al Baladi Hospital 9,585,023 9,365,516 4 Design and...7,331,585 237,490 688,906 8,257,981 8,258,377 8,258,377 3 Renovate Ibn Al Baladi Hospital 8,251,610 320,820 1,012,593 9,585,023 9,585,023

Differential Th17 response induced by the two clades of the pandemic ST258 Klebsiella pneumoniae clonal lineages producing KPC-type carbapenemase

PubMed Central

Clemente, Ann Maria; Castronovo, Giuseppe; Antonelli, Alberto; D’Andrea, Marco Maria; Tanturli, Michele; Perissi, Eloisa; Paccosi, Sara; Parenti, Astrid; Cozzolino, Federico; Rossolini, Gian Maria

2017-01-01

The spread of KPC-type carbapenemases is mainly attributed to the global dissemination of Klebsiella pneumoniae (KP) strains belonging to the clonal group (CG) 258, including sequence type (ST) 258 and other related STs. Two distinct clades of CG258-KP have evolved, which differ mainly for the composition of their capsular polysaccharides, and recent studies indicate that clade 1 evolved from an ancestor of clade 2 by recombination of a genomic fragment carrying the capsular polysaccharide (cps) locus. In this paper, we investigated the ability of two ST258-KP strains, KKBO-1 and KK207-1, selected as representatives of ST258-KP clade 2 and clade 1, respectively, to activate an adaptive immune response using ex vivo-stimulation of PBMC from normal donors as an experimental model. Our data showed that KKBO-1 (clade 2) induces a Th17 response more efficiently than KK207-1 (clade 1): the percentage of CD4+IL17+ cells and the production of IL-17A were significantly higher in cultures with KKBO-1 compared to cultures with KK207-1. While no differences in the rate of bacterial internalization or in the bacteria-induced expression of CD86 and HLA-DR by monocytes and myeloid dendritic cells were revealed, we found that the two strains significantly differ in inducing the production of cytokines involved in the adaptive immune response, as IL-1β, IL-23 and TNF-α, by antigen-presenting cells, with KKBO-1 being a more efficient inducer than KK207-1. The immune responses elicited by KK207-1 were comparable to those elicited by CIP 52.145, a highly virulent K. pneumoniae reference strain known to escape immune-inflammatory responses. Altogether, present results suggest that CG258-KP of the two clades are capable of inducing a different response of adaptive immunity in the human host. PMID:28586386

40 CFR 258.28 - Liquids restrictions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... septic waste; (2) The waste is leachate or gas condensate derived from the MSWLF unit and the MSWLF unit... leachate collection system as described in § 258.40(a)(2) of this part. The owner or operator must place...

40 CFR 258.28 - Liquids restrictions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... septic waste; (2) The waste is leachate or gas condensate derived from the MSWLF unit and the MSWLF unit... leachate collection system as described in § 258.40(a)(2) of this part. The owner or operator must place...

40 CFR 258.28 - Liquids restrictions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... septic waste; (2) The waste is leachate or gas condensate derived from the MSWLF unit and the MSWLF unit... leachate collection system as described in § 258.40(a)(2) of this part. The owner or operator must place...

258. Dennis Hill, Photographer April 1998 VIEW OF CANTILEVER TRUSS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

258. Dennis Hill, Photographer April 1998 VIEW OF CANTILEVER TRUSS ANCHOR ARM AT PIERS E- AND E-2, SOUTH SIDE, FACING NORTH. - San Francisco Oakland Bay Bridge, Spanning San Francisco Bay, San Francisco, San Francisco County, CA

40 CFR 258.25 - Access requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... wastes by using artificial barriers, natural barriers, or both, as appropriate to protect human health....25 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.25 Access requirements. Owners or operators of all...

40 CFR 258.12 - Wetlands.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Location Restrictions § 258.12 Wetlands. (a) New MSWLF units and lateral...) Impacts on fish, wildlife, and other aquatic resources and their habitat from release of the solid waste...

40 CFR 258.12 - Wetlands.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Location Restrictions § 258.12 Wetlands. (a) New MSWLF units and lateral...) Impacts on fish, wildlife, and other aquatic resources and their habitat from release of the solid waste...

40 CFR 258.24 - Air criteria.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.24 Air criteria. (a) Owners or operators of all MSWLFs... Act, as amended. (b) Open burning of solid waste, except for the infrequent burning of agricultural...

40 CFR 258.24 - Air criteria.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Operating Criteria § 258.24 Air criteria. (a) Owners or operators of all MSWLFs... Act, as amended. (b) Open burning of solid waste, except for the infrequent burning of agricultural...

50 CFR 216.258 - Renewal of Letters of Authorization.

Code of Federal Regulations, 2010 CFR

2010-10-01

... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND IMPORTING OF MARINE MAMMALS Taking Marine Mammals Incidental to Conducting Precision Strike Weapon Missions in the Gulf of Mexico § 216.258 Renewal of Letters of Authorization. (a) A Letter of Authorization...

40 CFR 258.54 - Detection monitoring program.

Code of Federal Regulations, 2010 CFR

2010-07-01

... FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.54 Detection... reaction products in the unsaturated zone beneath the MSWLF unit; (iii) The detectability of indicator parameters, waste constituents, and reaction products in the ground water; and (iv) The concentration or...

75 FR 258 - Airworthiness Directives; Bombardier, Inc. (Type Certificate Previously Held by Bombardier...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-05

....; Canadair) Model CL-600- 2B19 (Regional Jet Series 100 & 440) Airplanes AGENCY: Federal Aviation... the AD docket. List of Subjects in 14 CFR Part 39 Air transportation, Aircraft, Aviation safety..., January 5, 2010 / Proposed Rules#0;#0; [[Page 258

40 CFR 258.4 - Research, development, and demonstration permits.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS General § 258.4 Research, development, and... include such terms and conditions at least as protective as the criteria for municipal solid waste... and quantities of municipal solid waste and non-hazardous wastes which the State Director deems...

40 CFR 258.4 - Research, development, and demonstration permits.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS General § 258.4 Research, development, and... include such terms and conditions at least as protective as the criteria for municipal solid waste... and quantities of municipal solid waste and non-hazardous wastes which the State Director deems...

7 CFR 1924.258 - Notification of borrowers.

Code of Federal Regulations, 2014 CFR

2014-01-01

... REGULATIONS CONSTRUCTION AND REPAIR Complaints and Compensation for Construction Defects § 1924.258... frames for filing claims under this subpart. FmHA or its successor agency under Public Law 103-354 will also notify and advise borrowers of the construction defects procedure at any time construction defects...

7 CFR 1924.258 - Notification of borrowers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... REGULATIONS CONSTRUCTION AND REPAIR Complaints and Compensation for Construction Defects § 1924.258... frames for filing claims under this subpart. FmHA or its successor agency under Public Law 103-354 will also notify and advise borrowers of the construction defects procedure at any time construction defects...

7 CFR 1924.258 - Notification of borrowers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... REGULATIONS CONSTRUCTION AND REPAIR Complaints and Compensation for Construction Defects § 1924.258... frames for filing claims under this subpart. FmHA or its successor agency under Public Law 103-354 will also notify and advise borrowers of the construction defects procedure at any time construction defects...

7 CFR 1924.258 - Notification of borrowers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... REGULATIONS CONSTRUCTION AND REPAIR Complaints and Compensation for Construction Defects § 1924.258... frames for filing claims under this subpart. FmHA or its successor agency under Public Law 103-354 will also notify and advise borrowers of the construction defects procedure at any time construction defects...

7 CFR 1924.258 - Notification of borrowers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REGULATIONS CONSTRUCTION AND REPAIR Complaints and Compensation for Construction Defects § 1924.258... frames for filing claims under this subpart. FmHA or its successor agency under Public Law 103-354 will also notify and advise borrowers of the construction defects procedure at any time construction defects...

75 FR 12536 - City of Tenakee Springs; Notice of Declaration of Intention and Soliciting Comments, Protests...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-16

.... 47 S, R. 63 E, secs. 15, 21, and 22, Copper River Meridian. g. Filed Pursuant to: Section 23(b)(1) of..., Anchorage, AK 99503; telephone: (907) 258-2420; FAX: (907) 258-2419; e- mail: [email protected] . i...

GRS 1758-258: Into the thermal dominant state with Swift XRT

NASA Astrophysics Data System (ADS)

Hirsch, M.; Pottschmidt, K.; Krauss, F.; Eikmann, W.; Kreykenbohm, I.; Wilms, J.; Kuehnel, M.; Rodrigues, B. H. G.; Soria, R.; Grinberg, V.; Smith, D. M.; Bel, M. Cadolle; Tomsick, J. A.; Bodaghee, A.; Kuulkers, E.; INTEGRAL Galactic Bulge Monitoring Team; Kalemci, E.; Miller, J. M.

2016-12-01

A decline of the hard flux of the Galactic black hole candidate GRS 1758-258 was observed with Swift BAT and INTEGRAL ISGRI starting in 2016 mid-August, with the source having become undetectable above 20 keV around 2016 September 30 (ATEL #9625).

24 CFR 92.258 - Elder cottage housing opportunity (ECHO) units.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Housing and Urban Development HOME INVESTMENT PARTNERSHIPS PROGRAM Project Requirements § 92.258 Elder cottage housing opportunity (ECHO) units. (a) General. HOME funds may be used for the initial purchase and... designed to be installed adjacent to existing single-family dwellings. (b) Eligible owners. The owner of a...

40 CFR 258.56 - Assessment of corrective measures.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Assessment of corrective measures. 258... Assessment of corrective measures. (a) Within 90 days of finding that any of the constituents listed in... assessment of corrective measures. Such an assessment must be completed within a reasonable period of time...

40 CFR 258.56 - Assessment of corrective measures.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Assessment of corrective measures. 258... Assessment of corrective measures. (a) Within 90 days of finding that any of the constituents listed in... assessment of corrective measures. Such an assessment must be completed within a reasonable period of time...

40 CFR 258.56 - Assessment of corrective measures.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Assessment of corrective measures. 258... Assessment of corrective measures. (a) Within 90 days of finding that any of the constituents listed in... assessment of corrective measures. Such an assessment must be completed within a reasonable period of time...

40 CFR 258.61 - Post-closure care requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... the final cover; (2) Maintaining and operating the leachate collection system in accordance with the...) Maintaining and operating the gas monitoring system in accordance with the requirements of § 258.23. (b) The... stop managing leachate if the owner or operator demonstrates that leachate no longer poses a threat to...

40 CFR 258.3 - Consideration of other Federal laws.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Consideration of other Federal laws... CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS General § 258.3 Consideration of other Federal laws. The owner or operator of a municipal solid waste landfill unit must comply with any other applicable Federal...

40 CFR 258.3 - Consideration of other Federal laws.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Consideration of other Federal laws... CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS General § 258.3 Consideration of other Federal laws. The owner or operator of a municipal solid waste landfill unit must comply with any other applicable Federal...

40 CFR 258.3 - Consideration of other Federal laws.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Consideration of other Federal laws... CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS General § 258.3 Consideration of other Federal laws. The owner or operator of a municipal solid waste landfill unit must comply with any other applicable Federal...

8 CFR 258.3 - Action upon arrival.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS LIMITATIONS ON PERFORMANCE OF LONGSHORE WORK BY ALIEN CREWMEN § 258.3 Action upon arrival. (a) The master or agent of the vessel... the vessel will perform longshore work at any port before departing the United States; and (2) If...

40 CFR 258.71 - Financial assurance for closure.

Code of Federal Regulations, 2011 CFR

2011-07-01

....71 Section 258.71 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... closure. (a) The owner or operator must have a detailed written estimate, in current dollars, of the cost.... (1) The cost estimate must equal the cost of closing the largest area of all MSWLF unit ever...

40 CFR 258.71 - Financial assurance for closure.

Code of Federal Regulations, 2010 CFR

2010-07-01

....71 Section 258.71 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... closure. (a) The owner or operator must have a detailed written estimate, in current dollars, of the cost.... (1) The cost estimate must equal the cost of closing the largest area of all MSWLF unit ever...

40 CFR 258.16 - Closure of existing municipal solid waste landfill units.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Location Restrictions § 258.16 Closure of existing municipal solid waste landfill units. (a) Existing MSWLF units that cannot make the... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Closure of existing municipal solid...

40 CFR 258.16 - Closure of existing municipal solid waste landfill units.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Location Restrictions § 258.16 Closure of existing municipal solid waste landfill units. (a) Existing MSWLF units that cannot make the... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Closure of existing municipal solid...

RCRA SUBTITLE D (258): SEISMIC DESIGN GUIDANCE FOR MUNICIPAL SOLID WASTE LANDFILL FACILITIES

EPA Science Inventory

On October 9, 1993, the new RCRA Subtitle D regulations (40 CFR Part 258) went into effect. These regulations are applicable to landfills receiving municipal solid waste (MSW) and establish minimum Federal criteria for the siting, design, operation, and closure of MSW landfills....

40 CFR 258.54 - Detection monitoring program.

Code of Federal Regulations, 2014 CFR

2014-07-01

... FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.54 Detection... indicator parameters for a MSWLF unit, in lieu of some or all of the heavy metals (constituents 1-15 in... parameters, waste constituents, and reaction products in the ground water; and (iv) The concentration or...

40 CFR 258.54 - Detection monitoring program.

Code of Federal Regulations, 2013 CFR

2013-07-01

... FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.54 Detection... indicator parameters for a MSWLF unit, in lieu of some or all of the heavy metals (constituents 1-15 in... parameters, waste constituents, and reaction products in the ground water; and (iv) The concentration or...

40 CFR 258.54 - Detection monitoring program.

Code of Federal Regulations, 2012 CFR

2012-07-01

... FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.54 Detection... indicator parameters for a MSWLF unit, in lieu of some or all of the heavy metals (constituents 1-15 in... parameters, waste constituents, and reaction products in the ground water; and (iv) The concentration or...

40 CFR 258.54 - Detection monitoring program.

Code of Federal Regulations, 2011 CFR

2011-07-01

... FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective Action § 258.54 Detection... indicator parameters for a MSWLF unit, in lieu of some or all of the heavy metals (constituents 1-15 in... parameters, waste constituents, and reaction products in the ground water; and (iv) The concentration or...

40 CFR 258.58 - Implementation of the corrective action program.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective...) Establish and implement a corrective action ground-water monitoring program that: (i) At a minimum, meet the requirements of an assessment monitoring program under § 258.55; (ii) Indicate the effectiveness of the...

40 CFR 258.58 - Implementation of the corrective action program.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective...) Establish and implement a corrective action ground-water monitoring program that: (i) At a minimum, meet the requirements of an assessment monitoring program under § 258.55; (ii) Indicate the effectiveness of the...

40 CFR 258.58 - Implementation of the corrective action program.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Ground-Water Monitoring and Corrective...) Establish and implement a corrective action ground-water monitoring program that: (i) At a minimum, meet the requirements of an assessment monitoring program under § 258.55; (ii) Indicate the effectiveness of the...

40 CFR 239.6 - Permitting requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... CFR part 257, subpart B or 40 CFR part 258 federal revised criteria. (e) For municipal solid waste... solid waste landfill units shall have a permit incorporating the conditions identified in paragraph (e... solid waste landfill units which achieve compliance with 40 CFR part 258, subpart E; (vi) Closure and...

40 CFR 239.6 - Permitting requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... CFR part 257, subpart B or 40 CFR part 258 federal revised criteria. (e) For municipal solid waste... solid waste landfill units shall have a permit incorporating the conditions identified in paragraph (e... solid waste landfill units which achieve compliance with 40 CFR part 258, subpart E; (vi) Closure and...

40 CFR 239.6 - Permitting requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... CFR part 257, subpart B or 40 CFR part 258 federal revised criteria. (e) For municipal solid waste... solid waste landfill units shall have a permit incorporating the conditions identified in paragraph (e... solid waste landfill units which achieve compliance with 40 CFR part 258, subpart E; (vi) Closure and...

40 CFR 258.50 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-07-01

... in § 258.2) during the active life of the unit and the post-closure care period. This demonstration... shall be conducted throughout the active life and post-closure care period of that MSWLF unit as... scientist or engineer who has received a baccalaureate or post-graduate degree in the natural sciences or...

40 CFR 258.50 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... in § 258.2) during the active life of the unit and the post-closure care period. This demonstration... shall be conducted throughout the active life and post-closure care period of that MSWLF unit as... scientist or engineer who has received a baccalaureate or post-graduate degree in the natural sciences or...

40 CFR 258.50 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-07-01

... in § 258.2) during the active life of the unit and the post-closure care period. This demonstration... shall be conducted throughout the active life and post-closure care period of that MSWLF unit as... scientist or engineer who has received a baccalaureate or post-graduate degree in the natural sciences or...

40 CFR 258.50 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-07-01

... in § 258.2) during the active life of the unit and the post-closure care period. This demonstration... shall be conducted throughout the active life and post-closure care period of that MSWLF unit as... scientist or engineer who has received a baccalaureate or post-graduate degree in the natural sciences or...

8 CFR 210.2 - Application for temporary resident status.

Code of Federal Regulations, 2014 CFR

2014-01-01

... years or older, the application must be accompanied by a completed Form FD-258 (Fingerprint Card). (ii... applicant shall proceed to a legalization office for presentation or completion of Form FD-258 (Fingerprint... certificate accompanied by additional evidence of identity bearing a photograph and/or fingerprint of the...

8 CFR 210.2 - Application for temporary resident status.

Code of Federal Regulations, 2013 CFR

2013-01-01

... years or older, the application must be accompanied by a completed Form FD-258 (Fingerprint Card). (ii... applicant shall proceed to a legalization office for presentation or completion of Form FD-258 (Fingerprint... certificate accompanied by additional evidence of identity bearing a photograph and/or fingerprint of the...

8 CFR 210.2 - Application for temporary resident status.

Code of Federal Regulations, 2012 CFR

2012-01-01

... years or older, the application must be accompanied by a completed Form FD-258 (Fingerprint Card). (ii... applicant shall proceed to a legalization office for presentation or completion of Form FD-258 (Fingerprint... certificate accompanied by additional evidence of identity bearing a photograph and/or fingerprint of the...

40 CFR 258.51 - Ground-water monitoring systems.

Code of Federal Regulations, 2010 CFR

2010-07-01

... the uppermost aquifer (as defined in § 258.2) that: (1) Represent the quality of background ground water that has not been affected by leakage from a unit. A determination of background quality may...; or (ii) Sampling at other wells will provide an indication of background ground-water quality that is...

40 CFR 258.42 - Approval of site-specific flexibility requests in Indian country.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Design Criteria § 258.42 Approval of...) of this section applies to the Salt River Landfill, a municipal solid waste landfill owned and operated by the SPRMIC on the SRPMIC's reservation in Arizona, which includes waste disposal areas...

40 CFR 258.42 - Approval of site-specific flexibility requests in Indian country.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) SOLID WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Design Criteria § 258.42 Approval of...) of this section applies to the Salt River Landfill, a municipal solid waste landfill owned and operated by the SPRMIC on the SRPMIC's reservation in Arizona, which includes waste disposal areas...

Performance Characteristics of Automotive Engines in the United States : First Series - Report No. 13 - 1975 American Motors 258 CID (4.2 Liters)

DOT National Transportation Integrated Search

1978-04-01

Experimental data were obtained in dynamometer tests of a 1975 AMC 258-CID production 1V engine to determine fuel consumption and emissions (hydrocarbon, carbon monoxide, oxides of nitrogen) at steady-state engine-operating modes. The objective of th...

77 FR 2317 - Captain John Smith Chesapeake National Historic Trail Advisory Council

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-17

... 1, 2012 via email at [email protected] or telephone: (757) 258-8914; a written summary of... provide public comment should register prior to February 1, 2012 via email at [email protected] or telephone: (757) 258-8914. For those wishing to make comments, please provide a written summary of your...

The Role of Epidemic Resistance Plasmids and International High-Risk Clones in the Spread of Multidrug-Resistant Enterobacteriaceae

PubMed Central

Mathers, Amy J.; Peirano, Gisele

2015-01-01

SUMMARY Escherichia coli sequence type 131 (ST131) and Klebsiella pneumoniae ST258 emerged in the 2000s as important human pathogens, have spread extensively throughout the world, and are responsible for the rapid increase in antimicrobial resistance among E. coli and K. pneumoniae strains, respectively. E. coli ST131 causes extraintestinal infections and is often fluoroquinolone resistant and associated with extended-spectrum β-lactamase production, especially CTX-M-15. K. pneumoniae ST258 causes urinary and respiratory tract infections and is associated with carbapenemases, most often KPC-2 and KPC-3. The most prevalent lineage within ST131 is named fimH30 because it contains the H30 variant of the type 1 fimbrial adhesin gene, and recent molecular studies have demonstrated that this lineage emerged in the early 2000s and was then followed by the rapid expansion of its sublineages H30-R and H30-Rx. K. pneumoniae ST258 comprises 2 distinct lineages, namely clade I and clade II. Moreover, it seems that ST258 is a hybrid clone that was created by a large recombination event between ST11 and ST442. Epidemic plasmids with blaCTX-M and blaKPC belonging to incompatibility group F have contributed significantly to the success of these clones. E. coli ST131 and K. pneumoniae ST258 are the quintessential examples of international multidrug-resistant high-risk clones. PMID:25926236

Low completion rate of hepatitis B vaccination in female sex workers.

PubMed

Magalhães, Rosilane de Lima Brito; Teles, Sheila Araújo; Reis, Renata Karina; Galvão, Marli Teresinha Gimeniz; Gir, Elucir

2017-01-01

to assess predictive factors for noncompletion of the hepatitis B vaccination schedule in female sex workers in the city of Teresina, Northeastern Brazil. 402 women were interviewed and, for those who did not wish to visit specialized sites, or did not know their hepatitis B vaccination status, the vaccine was offered at their workplaces. Bi- and multivariate analyses were performed to identify potential predictors for noncompletion of the vaccination schedule. of the 284 women eligible for vaccination, 258 (90.8%) received the second dose, 157/258 (60.8%) and 68/258 (26.3%) received the second and third doses, respectively. Working at clubs and consuming illicit drugs were predictors for noncompletion of the vaccination schedule. the high acceptability of the vaccine's first dose, associated with low completion rates of the vaccination schedule in sex workers, shows the need for more persuasive strategies that go beyond offering the vaccine at their workplaces. avaliar fatores preditores de não completude do esquema vacinal contra hepatite B em mulheres que se prostituem em Teresina, Nordeste do Brasil. Um total de 402 mulheres foi entrevistado e, para as que se negaram a irem a lugares especializados, ou desconheciam sua situação vacinal contra hepatite B, a vacina foi oferecida no local do trabalho. Análises bi e multivariadas foram realizadas para identificar potenciais preditores de não completude do esquema vacinal. Das 284 mulheres elegíveis para vacinação, 258 (90,8%) receberam a primeira dose, 157/258 (60,8%) e 68/258 (26,3%) receberam a segunda e terceira doses. Trabalhar em boates e consumir drogas ilícitas foram preditores de não completude do esquema vacinal (p<0,05). A elevada aceitabilidade da primeira dose da vacina, associada à baixa completude do esquema vacinal em profissionais do sexo, evidencia a necessidade de estratégia mais persuasiva que vá além da oferta da vacina no local de trabalho.

Factors That Affect Oxygen Activation and Coupling of the Two Redox Cycles in the Aromatization Reaction Catalyzed by NikD, an Unusual Amino Acid Oxidase

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kommoju, Phaneeswara-Rao; Bruckner, Robert C.; Ferreira, Patricia

2009-10-21

NikD is a flavoprotein oxidase that catalyzes the oxidation of piperideine-2-carboxylate (P2C) to picolinate in a remarkable aromatization reaction comprising two redox cycles and at least one isomerization step. Tyr258 forms part of an 'aromatic cage' that surrounds the ring in picolinate and its precursors. Mutation of Tyr258 to Phe does not perturb the structure of nikD but does affect the coupling of the two redox cycles and causes a 10-fold decrease in turnover rate. Tyr258Phe catalyzes a quantitative two-electron oxidation of P2C, but only 60% of the resulting dihydropicolinate intermediate undergoes a second redox cycle to produce picolinate. Themore » mutation does not affect product yield with an alternate substrate (3,4-dehydro-l-proline) that is aromatized in a single two-electron oxidation step. Wild-type and mutant enzymes exhibit identical rate constants for oxidation of P2C to dihydropicolinate and isomerization of a reduced enzyme-dihydropicolinate complex. The observed rates are 200- and 10-fold faster, respectively, than the mutant turnover rate. Release of picolinate from Tyr258Phe is 100-fold faster than turnover. The presence of a bound substrate or product is a key factor in oxygen activation by wild-type nikD, as judged by the 10-75-fold faster rates observed for complexes of the reduced enzyme with picolinate, benzoate, or 1-cyclohexenoate, a 1-deaza-P2C analogue. The reduced Tyr258Phe-1-cyclohexenoate complex is 25-fold less reactive with oxygen than the wild-type complex. We postulate that mutation of Tyr258 causes subtle changes in active site dynamics that promote release of the reactive dihydropicolinate intermediate and disrupt the efficient synchronization of oxygen activation observed with wild-type nikD.« less

p38α phosphorylates serine 258 within the cytoplasmic domain of tissue factor and prevents its incorporation into cell-derived microparticles.

PubMed

Ettelaie, Camille; Elkeeb, Azza M; Maraveyas, Anthony; Collier, Mary Elizabeth W

2013-03-01

We previously showed that the phosphorylation of Ser253 within the cytoplasmic domain of human tissue factor (TF) initiates the incorporation and release of this protein into cell-derived microparticles. Furthermore, subsequent phosphorylation of Ser258 terminates this process. However, the identity of the kinase responsible for the phosphorylation of Ser258 and mode of action of this enzyme remain unknown. In this study, p38α was identified as the proline-directed kinase capable of phosphorylating Ser258 specifically, and without any detectable activity towards Ser253. Furthermore, using synthetic peptides, it was shown that the Km for the reaction decreased by approximately 10 fold on substitution of Ser253 with phospho-Ser253. Either inhibition of p38 using SB202190 or knockdown of p38α expression in coronary artery endothelial cells overexpressing wild-type TF, resulted in decreased phosphorylation of Ser258, following activation of cells with PAR2-agonist peptide (PAR2-AP). In agreement with our previous data, inhibition of phosphorylation of this residue maintained the release of TF. Activation of PAR2 in cells transfected to overexpress TF, resulted in two separate peaks of p38 activity at approximately 40 and 120 min post-activation. Furthermore, overexpression of Ala253-substituted TF enhanced the second p38 activation peak. However, the second peak was absent in cells devoid of TF or in cells overexpressing the Asp253-substituted TF. Our data clearly identifies p38α as a kinase capable of phosphorylating Ser258 within the cytoplasmic domain of TF. Moreover, it appears that the presence of TF within the cells regulates the late activation of p38 and consequently the termination of TF release into microparticles. Copyright © 2012 Elsevier B.V. All rights reserved.

[Path analysis of lifestyle habits to the metabolic syndrome].

PubMed

Zhu, Zhen-xin; Zhang, Cheng-qi; Tang, Fang; Song, Xin-hong; Xue, Fu-zhong

2013-04-01

To evaluate the relationship between lifestyle habits and the components of metabolic syndrome (MS). Based on the routine health check-up system in a certain Center for Health Management of Shandong Province, a longitudinal surveillance health check-up cohort from 2005 to 2010 was set up. There were 13 225 urban workers in Jinan included in the analysis. The content of the survey included demographic information, medical history, lifestyle habits, body mass index (BMI) and the level of blood pressure, fasting blood-glucose, and blood lipid, etc. The distribution of BMI, blood pressure, fasting blood-glucose, blood lipid and lifestyle habits between MS patients and non-MS population was compared, latent variables were extracted by exploratory factor analysis to determine the structure model, and then a partial least squares path model was constructed between lifestyle habits and the components of MS. Participants'age was (46.62 ± 12.16) years old. The overall prevalence of the MS was 22.43% (2967/13 225), 26.49% (2535/9570) in males and 11.82% (432/3655) in females. The prevalence of the MS was statistically different between males and females (χ(2) = 327.08, P < 0.01). Between MS patients and non-MS population, the difference of dietary habits was statistically significant (χ(2) = 166.31, P < 0.01) in MS patients, the rate of vegetarian, mixed and animal food was 23.39% (694/2967), 42.50% (1261/2967) and 34.11% (1012/2967) respectively, while in non-MS population was 30.80% (3159/10 258), 46.37% (4757/10 258), 22.83% (2342/10 258) respectively. Their alcohol consumption has statistical difference (χ(2) = 374.22, P < 0.01) in MS patients, the rate of never or past, occasional and regular drinking was 27.37% (812/2967), 24.71% (733/2967), 47.93% (1422/2967) respectively, and in non-MS population was 39.60% (4062/10 258), 31.36% (3217/10 258), 29.04% (2979/10 258) respectively. The difference of their smoking status was statistically significant (χ(2) = 115.86, P < 0.01) in MS patients, the rate of never or past, occasional and regular smoking was 59.72% (1772/2967), 6.24% (185/2967), 34.04% (1010/2967) respectively, while in non-MS population was 70.03% (7184/10 258), 5.35% (549/10 258), 24.61% (2525/10 258) respectively. Both lifestyle habits and the components of MS were attributable to only one latent variable. After adjustment for age and gender, the path coefficient between the latent component of lifestyle habits and the latent component of MS was 0.22 with statistical significance (t = 6.46, P < 0.01) through bootstrap test. Reliability and validity of the model:the lifestyle latent variable: average variance extracted was 0.53, composite reliability was 0.77 and Cronbach's a was 0.57. The MS latent variable: average variance extracted was 0.45, composite reliability was 0.76 and Cronbach's a was 0.59. Unhealthy lifestyle habits are closely related to MS. Meat diet, excessive drinking and smoking are risk factors for MS.

77 FR 69781 - Enhanced Natural Gas Market Transparency

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-21

... be filed in native applications or print-to-PDF format and not in a scanned format, at http://www.... FERC, 661 F.3d 258 (5th Cir. 2011). \\17\\ Order Granting Motion to Clarify Opinion, Texas Pipelines Ass'n v. FERC, 661 F.3d 258 (Dec. 20. 2011). 8. In addition to adding the natural gas market...

40 CFR 466.13 - New source performance standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Oil and grease 100.0 12.60 100.0 12.60 TSS 150.0 18.91 120.0 15.12 pH (1) (1) (1) (1) English units....87 0.36 Oil and grease 20.48 2.58 20.48 2.58 TSS 30.72 3.87 24.58 3.10 pH (1) (1) (1) (1) 1 Within...

40 CFR 466.13 - New source performance standards.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Oil and grease 100.0 12.60 100.0 12.60 TSS 150.0 18.91 120.0 15.12 pH (1) (1) (1) (1) English units....87 0.36 Oil and grease 20.48 2.58 20.48 2.58 TSS 30.72 3.87 24.58 3.10 pH (1) (1) (1) (1) 1 Within...

40 CFR 466.13 - New source performance standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Oil and grease 100.0 12.60 100.0 12.60 TSS 150.0 18.91 120.0 15.12 pH (1) (1) (1) (1) English units....87 0.36 Oil and grease 20.48 2.58 20.48 2.58 TSS 30.72 3.87 24.58 3.10 pH (1) (1) (1) (1) 1 Within...

77 FR 58773 - Drawbridge Operation Regulations; James River, Newport News, VA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-24

... Operation Regulations; James River, Newport News, VA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary... schedule that governs the US 17/258 Bridge across the James River, mile 5.0, at Newport News, VA. The... 17/258 Bridge over the James River, mile 5.0, at Newport News, VA opens on signal as required by 33...

37 CFR 258.3 - Royalty fee for secondary transmission of analog signals of broadcast stations by satellite...

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Royalty fee for secondary... AND PROCEDURES ADJUSTMENT OF ROYALTY FEE FOR SECONDARY TRANSMISSIONS BY SATELLITE CARRIERS § 258.3 Royalty fee for secondary transmission of analog signals of broadcast stations by satellite carriers. (a...

77 FR 61428 - Notice of Meeting for Star-Spangled Banner National Historic Trail Advisory Council

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-09

... preregister via email at [email protected] or telephone: (757) 258-8914; a written summary of comments... public comment session should register via email at [email protected] or telephone: (757) 258-8914. For those wishing to make comments, please provide a written summary of your comments prior to the...

77 FR 64352 - Notice of Meeting for Captain John Smith Chesapeake National Historic Trail Advisory Council

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-19

... should preregister via email at [email protected] or telephone: (757) 258-8914; a written summary... meeting and/or participate in the public comment session should register via email at [email protected] or telephone: (757) 258-8914. For those wishing to make comments, please provide a written summary...

78 FR 59368 - Notice of Joint Meeting for Captain John Smith Chesapeake National Historic Trail Advisory...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-26

... comment for the public comment session should register via email to [email protected] or telephone (757) 258-8914. For those wishing to make comments, please provide a written summary of your comments...) 258-8914 or email [email protected] . SUPPLEMENTARY INFORMATION: Under section 10(a)(2) of the...

A comparative study of burnout syndrome among health professionals in a Nigerian teaching hospital.

PubMed

Olley, B O

2003-09-01

Burnout as a measure of stress has generated research interest in the past two decades. However, there is a dearth of research on this interesting and important phenomenon in Nigeria. This study compared burnout and its associated factors in various health professionals working at the University College Hospital, Ibadan, Nigeria. Two hundred and sixty health care providers were sampled from 5 main units: Theatre/Intensive Care Unit (ICU), Accident and Emergency (A & E), Oncology, Dentistry and General Outpatients Department (GOP), among others. Included were 104 nurses (40%), 83 doctors (31.9%), 21 pharmacists/pharmacy technicians (8.0%), 10 medical social workers (3.8%) and 42 nursing assistants (16.1%). Outcome measures included the Maslach Burnout Inventory (MBI), the 30-item General Health Questionnaire (GHQ) and the Spielberger State Trait Anxiety Inventory (STAI). Core findings indicated that nurses consistently reported higher scores on all measures of burnout: exhaustion (F = 3.60, df = 258, P < .05); accomplishment (F = 3.94, df = 258, P < .05) and depersonalization (F = 4.58, df 258, P < .01) when compared with other health care providers. Significant differences were also noted between nurses and all other care providers in total scores on the General Health Questionnaire (F = 6.54, df 258, P < .01) and the State Trait Anxiety Inventory (F = 1.91, df 258, P < .05), respectively. These results are discussed in relation to the existing literature on burnout in Nigeria. Further empirical study is highly suggested in view of dearth of studies on the occupational health of health care providers in Nigeria.

76 FR 17859 - Notice of Public Information Collection(s) Being Reviewed by the Federal Communications...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-31

... required by the Paperwork Reduction Act (PRA) of 1995, 44 U.S.C. 3501-3520. Comments are requested... accuracy of the Commission's burden estimate; (c) ways to enhance the quality, utility, and clarity of the... is found at Sec. 258 [47 U.S.C. 258] Illegal Changes In Subscriber Carrier Selections, Public Law 104...

76 FR 17861 - Notice of Public Information Collection(s) Being Reviewed by the Federal Communications...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-31

... required by the Paperwork Reduction Act (PRA) of 1995, 44 U.S.C. 3501-3520. Comments are requested... accuracy of the Commission's burden estimate; (c) ways to enhance the quality, utility, and clarity of the... is found at Section 258 [47 U.S.C. 258] Illegal Changes in Subscriber Carrier Selections, Public Law...

The Pax gene family: Highlights from cephalopods

PubMed Central

Baratte, Sébastien; Andouche, Aude; Bonnaud-Ponticelli, Laure

2017-01-01

Pax genes play important roles in Metazoan development. Their evolution has been extensively studied but Lophotrochozoa are usually omitted. We addressed the question of Pax paralog diversity in Lophotrochozoa by a thorough review of available databases. The existence of six Pax families (Pax1/9, Pax2/5/8, Pax3/7, Pax4/6, Paxβ, PoxNeuro) was confirmed and the lophotrochozoan Paxβ subfamily was further characterized. Contrary to the pattern reported in chordates, the Pax2/5/8 family is devoid of homeodomain in Lophotrochozoa. Expression patterns of the three main pax classes (pax2/5/8, pax3/7, pax4/6) during Sepia officinalis development showed that Pax roles taken as ancestral and common in metazoans are modified in S. officinalis, most likely due to either the morphological specificities of cephalopods or to their direct development. Some expected expression patterns were missing (e.g. pax6 in the developing retina), and some expressions in unexpected tissues have been found (e.g. pax2/5/8 in dermal tissue and in gills). This study underlines the diversity and functional plasticity of Pax genes and illustrates the difficulty of using probable gene homology as strict indicator of homology between biological structures. PMID:28253300

40 CFR 264.258 - Closure and post-closure care.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Waste Piles § 264.258 Closure and post-closure care. (a) At closure, the owner or operator must remove... that apply to landfills (§ 264.310). (c)(1) The owner or operator of a waste pile that does not comply...(c) or § 264.251(b), must: (i) Include in the closure plan for the pile under § 264.112 both a plan...

40 CFR 466.43 - New source performance standards.

Code of Federal Regulations, 2013 CFR

2013-07-01

....55 10.60 0.79 Oil and grease 168.23 12.60 168.23 12.60 TSS 252.35 18.91 201.88 15.12 pH (1) (1) (1....32 Iron 4.24 0.32 2.17 0.16 Oil and grease 34.46 2.58 34.46 2.58 TSS 51.69 3.87 41.35 3.10 pH (1) (1...

42 CFR 137.258 - Does the Self-Governance Tribe have a right to a hearing prior to a non-immediate reassumption...

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Does the Self-Governance Tribe have a right to a... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Reassumption § 137.258 Does the Self-Governance Tribe...

Targeting fibroblast growth factor receptors blocks PI3K/AKT signaling, induces apoptosis, and impairs mammary tumor outgrowth and metastasis.

PubMed

Dey, Julien H; Bianchi, Fabrizio; Voshol, Johannes; Bonenfant, Debora; Oakeley, Edward J; Hynes, Nancy E

2010-05-15

Members of the fibroblast growth factor receptor (FGFR) family have essential roles in normal physiology and in cancer where they control diverse processes. FGFRs have been associated with breast cancer development. Thus, models to study the role of FGFR in breast cancer and their targeting potential are important. We present an in vitro and in vivo analysis of FGFRs in the breast cancer model cell lines 67NR and 4T1. We show that both tumor cell lines coexpress FGFRs and ligands and display autocrine FGFR signaling activity. Fibroblast growth factor receptor substrate 2 (FRS2), a downstream mediator of FGFR, is constitutively tyrosine phosphorylated and multiple signaling pathways are active. Treatment of 67NR and 4T1 cultures with TKI258, an FGFR tyrosine kinase inhibitor (TKI), caused a rapid decrease in FRS2 phosphorylation; decreased the activity of extracellular signal-regulated kinase 1/2 (ERK1/2), AKT, and phospholipase Cgamma; and blocked proliferation of both tumor lines. Furthermore, TKI258 induced 4T1 apoptotic cell death via blockade of the phosphoinositide 3-kinase/AKT pathway. In vivo, one dose of TKI258 rapidly lowered FRS2 phosphorylation and ERK1/2 and AKT activity in mammary tumors. Long-term TKI258 treatment of 4T1 tumor- and 67NR tumor-bearing mice had a significant effect on primary tumor outgrowth and 4T1 tumor-induced lung metastases. A microarray analysis was carried out to identify targets with roles in TKI258 antitumor activity and potential prognostic markers in human breast tumors. Of interest are the downregulated matrix metalloproteases (MMP), in particular MMP9, which is essential for metastatic spread of 4T1 tumors. (c)2010 AACR.

Are All Heat Loads Created Equal?

PubMed

Meade, Robert D; Kenny, Glen P

2017-09-01

We evaluated physiological responses during exercise at a fixed evaporative requirement for heat balance (Ereq) but varying combinations of metabolic and environmental heat load. Nine healthy, physically active males (age: 46 ± 8 yr) performed four experimental sessions consisting of 75 min of semirecumbent cycling at various ambient temperatures. Whole-body dry heat loss (direct calorimetry) was monitored continuously as was heat production (indirect calorimetry), which was adjusted to achieve an Ereq of 400 W. The resultant metabolic heat productions and ambient temperatures for the sessions were as follows: (i) 440 W and 30°C (440 [30]), (ii) 388 W and 35°C (388 [35]), (iii) 317 W and 40°C (317 [40]), and (iv) 258 W and 45°C (258 [45]). Whole-body evaporative heat loss was determined via direct calorimetry. Esophageal (Tes) and mean skin (Tsk) temperatures as well as HR were monitored continuously. Mean body temperature (Tb) was calculated from Tes and Tsk. Physiological strain index (PSI) was determined from Tes and HR. End-exercise evaporative heat loss and Tb were similar between conditions (both P ≥ 0.48). Tes was greater in 440 [30] (37.67°C ± 0.04°C) and 388 [35] (37.58°C ± 0.07°C) relative to both 317 [40] (37.35°C ± 0.06°C) and 258 [45] (37.20°C ± 0.07°C; all P ≤ 0.05). Further, Tsk was different between each condition (440 [30], 33.85°C ± 0.16°C; 388 [35], 34.53°C ± 0.08°C; 317 [40], 35.67°C ± 0.07°C; and 258 [45], 36.54°C ± 0.08°C; all P < 0.01). In 440 [30], HR was elevated by about 13 and 18 bpm relative to 317 [40] and 258 [45], respectively (both P < 0.01). Finally, PSI was greater in both 440 [30] and 388 [35] compared with 317 [40] and 258 [45] (all P ≤ 0.04). Exercise at a fixed Ereq resulted in similar evaporative heat loss and Tb. However, the Tes, Tsk, HR, and PSI responses varied depending on the relative contribution of metabolic and environmental heat load.

Multiple animal studies for medical chemical defense program in soldier/patient decontamination and drug development on task order 86-25: Evaluation of the effectiveness of two ROHM and HAAS candidate decontamination systems against percutaneous application of undiluted TGD, Gd, VX HD, and L on the laboratory albino rabbit. Final report, 1 September 1986-1 February 1987

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joiner, R.L.; Keys, W.B.; Harroff, H.H.

1988-02-18

A task was assigned to Battelle's Medical Research and Evaluation Facility(MREF) to evaluate the effectiveness of two candidate decontamination systems when compared to the standard dual component M258A1 decontamination system currently fielded by the U.S. Army. The chemical surety material (CSM) used in the evaluation were the organophosphates Soman (GD), polymer thickened GD (TGD), and VX, and the vesicants sulfur mustard (HD) and Lewisite (LS). The efficacies of the two candidate decontamination systems were evaluated in such a manner as to determine the LD50 and protective ratio (PR) for each decontaminant against each organophosphate CSM as compared to the standardmore » M258A1 decontamination system LD50. The PR constituted a comparison for each candidate system against the M258A1 standard. In the vesicant phase of the screen, the efficacies of the candidate systems were evaluated in a side-by-side comparison to the M258A1 decontamination system to determine whether the candidates were as good as or better than the standard dual component system.« less

Emergence of Carbapenemase Producing Klebsiella Pneumonia and Spread of KPC-2 and KPC-17 in Taiwan: A Nationwide Study from 2011 to 2013.

PubMed

Tseng, I-Ling; Liu, Yu-Mei; Wang, Shiow-Jen; Yeh, Hung-Yi; Hsieh, Chia-Lun; Lu, Hsueh-Lin; Tseng, Yu-Chuan; Mu, Jung-Jung

2015-01-01

The emergence of carbapenemase-producing Klebsiella pneumoniae (CPKP) has become a great concern worldwide. In this study, 994 non-duplicate, carbapenem non-susceptible Klebsiella pneumonia isolates were collected in Taiwan from 2011 to 2013 for detection of the carbapenemase genes, assessment of antimicrobial susceptibility and molecular epidemiology studies. Of these 994 isolates, 183 (18.4%) had carbapenemase genes: 157 (15.8%) KPC (145 KPC-2 and 12 KPC-17), 16 (1.6%) IMP-8, 9 (0.9%) VIM-1, and 1 (0.1%) NDM-1. KPC had the highest prevalence rate among the carbapenemases and represented a major epidemic clone circulating in Taiwan. The ST512 and ST258 KPC-2 KPs were first identified in Taiwan and were grouped into a small cluster in the PFGE profile. In addition, the genetic structure encompassing the blaKPC gene of the ST512 and ST258 isolates showed a different pattern from that of other KPC isolates. ST11 may be a major sequence type circulating in Taiwan, although a specific minor clone has begun to be observed. This is the first report of ST258 and ST512 KPC-2 KP isolates in Taiwan, whether ST258 and ST512 will become the next endemic problems in Taiwan should be closely monitored.

Klebsiella pneumoniae Carbapenemase (KPC)-Producing K. pneumoniae at a Single Institution: Insights into Endemicity from Whole-Genome Sequencing

PubMed Central

Stoesser, Nicole; Sheppard, Anna E.; Pankhurst, Louise; Giess, Adam; Yeh, Anthony J.; Didelot, Xavier; Turner, Stephen D.; Sebra, Robert; Kasarskis, Andrew; Peto, Tim; Crook, Derrick; Sifri, Costi D.

2015-01-01

The global emergence of Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-Kp) multilocus sequence type ST258 is widely recognized. Less is known about the molecular and epidemiological details of non-ST258 K. pneumoniae in the setting of an outbreak mediated by an endemic plasmid. We describe the interplay of blaKPC plasmids and K. pneumoniae strains and their relationship to the location of acquisition in a U.S. health care institution. Whole-genome sequencing (WGS) analysis was applied to KPC-Kp clinical isolates collected from a single institution over 5 years following the introduction of blaKPC in August 2007, as well as two plasmid transformants. KPC-Kp from 37 patients yielded 16 distinct sequence types (STs). Two novel conjugative blaKPC plasmids (pKPC_UVA01 and pKPC_UVA02), carried by the hospital index case, accounted for the presence of blaKPC in 21/37 (57%) subsequent cases. Thirteen (35%) isolates represented an emergent lineage, ST941, which contained pKPC_UVA01 in 5/13 (38%) and pKPC_UVA02 in 6/13 (46%) cases. Seven (19%) isolates were the epidemic KPC-Kp strain, ST258, mostly imported from elsewhere and not carrying pKPC_UVA01 or pKPC_UVA02. Using WGS-based analysis of clinical isolates and plasmid transformants, we demonstrate the unexpected dispersal of blaKPC to many non-ST258 lineages in a hospital through spread of at least two novel blaKPC plasmids. In contrast, ST258 KPC-Kp was imported into the institution on numerous occasions, with other blaKPC plasmid vectors and without sustained transmission. Instead, a newly recognized KPC-Kp strain, ST941, became associated with both novel blaKPC plasmids and spread locally, making it a future candidate for clinical persistence and dissemination. PMID:25561339

Ocean Engineering Studies Compiled 1991. Volume 11. Pressure-Resistant Glass Light Enclosures

DTIC Science & Technology

1991-01-01

resting on this gasket than when they were resting on bare type 316 stainless steel end closures, aluminum gasket, or glass fiber- phenolic laminate ...316 2.58 inches thick Brass (naval) 2.58 inches thick Titanium (Ti-6AI-4V) 1.82 inches thick Phenolic resin-glass fiber laminate 4.40 inches thick...The 6061-T6 aluminum and the 94 spcimen s phenolic resin-impregnated glass fiber 18,000 imploded at -- /- laminate materials performed the best 18,000

First Isolate of KPC-2-Producing Klebsiella pneumonaie Sequence Type 23 from the Americas

PubMed Central

Cejas, Daniela; Fernández Canigia, Liliana; Rincón Cruz, Giovanna; Elena, Alan X.; Maldonado, Ivana; Gutkind, Gabriel O.

2014-01-01

KPC-2-producing Klebsiella pneumoniae isolates mainly correspond to clonal complex 258 (CC258); however, we describe KPC-2-producing K. pneumoniae isolates belonging to invasive sequence type 23 (ST23). KPC-2 has scarcely been reported to occur in ST23, and this report describes the first isolation of this pathogen in the Americas. Acquisition of resistant markers in virulent clones could mark an evolutionary step toward the establishment of these clones as major nosocomial pathogens. PMID:25031447

THE VARIABLE NEAR-INFRARED COUNTERPART OF THE MICROQUASAR GRS 1758–258

DOE Office of Scientific and Technical Information (OSTI.GOV)

Luque-Escamilla, Pedro L.; Martí, Josep; Muñoz-Arjonilla, Álvaro J., E-mail: peter@ujaen.es, E-mail: jmarti@ujaen.es, E-mail: ajmunoz@ujaen.es

2014-12-10

We present a new study of the microquasar system GRS 1758–258 in the near-infrared domain based on archival observations with the Hubble Space Telescope and the NICMOS camera. In addition to confirming the near-infrared counterpart pointed out by Muñoz-Arjonilla et al., we show that this object displays significant photometric variability. From its average magnitudes, we also find that GRS 1758–258 fits well within the correlation between the optical/near-infrared and X-ray luminosity known to exist for low-mass, black-hole candidate X-ray binaries in a hard state. Moreover, the spectral energy distribution built using all radio, near-infrared, and X-ray data available closest inmore » time to the NICMOS observations can be reasonably interpreted in terms of a self-absorbed radio jet and an irradiated accretion disk model around a stellar-mass black hole. All these facts match the expected behavior of a compact binary system and strengthen our confidence in the counterpart identification.« less

Long-Term Multiwavelength Observations of GRS 1758-258 and the Advection-dominated Accretion Flow Model

NASA Astrophysics Data System (ADS)

Keck, John W.; Craig, William W.; Hailey, Charles J.; Harrison, Fiona; Hong, Jae Sub; Kahn, Steven M.; Lubin, Philip M.; McLean, Ryan; Pivovaroff, Michael J.; Seiffert, Michael; Wurtz, Ron; Ziock, Klaus P.

2001-12-01

We present a long-term multiwavelength light curve of Galactic black hole candidate GRS 1758-258 by combining previously published and archival data from Granat, ROSAT, the Compton Gamma Ray Observatory, the Rossi X-Ray Timing Explorer, BeppoSAX, ASCA, EXOSAT, and the Very Large Array. In addition, we include the first spectral results from the balloon-borne Gamma-Ray Arcminute Telescope Imaging System (GRATIS). In light of divergent analyses of the 1991-1993 ROSAT observations, we have reanalyzed these data; we find that the soft X-rays track the hard X-rays and that the fits require no blackbody component-indicating that GRS 1758-258 did not go to the high state in 1993. We offer an interpretation of these long-baseline data based on the advection-dominated accretion flow (ADAF) model for a system with m<~mcrit. We find that the 1990-1993 coeval hard and soft X-ray observations support the ADAF predictions. We discuss a new way to constrain black hole mass with spectral data and the ADAF theory and apply this technique to GRS 1758-258 to find M1>~8-9 Msolar at an assumed distance of 8.5 kpc. Further investigations of the ADAF model allow us to evaluate the model critically against the 1996 data and flux-flux diagram of Barret, McClintock, & Grindlay and to understand the limits of the latter's ``X-ray burster box.''

40 CFR 466.13 - New source performance standards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... and grease 100.0 12.60 100.0 12.60 TSS 150.0 18.91 120.0 15.12 pH (1) (1) (1) (1) English units—pounds... Nickel 2.46 0.31 1.29 0.16 Zinc 2.09 0.27 0.86 0.11 Aluminum 6.21 0.78 2.54 0.32 Iron 5.74 0.72 2.87 0.36 Oil and grease 20.48 2.58 20.48 2.58 TSS 30.72 3.87 24.58 3.10 pH (1) (1) (1) (1) 1 Within the range 7...

40 CFR 466.13 - New source performance standards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... and grease 100.0 12.60 100.0 12.60 TSS 150.0 18.91 120.0 15.12 pH (1) (1) (1) (1) English units—pounds... Nickel 2.46 0.31 1.29 0.16 Zinc 2.09 0.27 0.86 0.11 Aluminum 6.21 0.78 2.54 0.32 Iron 5.74 0.72 2.87 0.36 Oil and grease 20.48 2.58 20.48 2.58 TSS 30.72 3.87 24.58 3.10 pH (1) (1) (1) (1) 1 Within the range 7...

Transmission Line for 258 GHz Gyrotron DNP Spectrometry

NASA Astrophysics Data System (ADS)

Bogdashov, Alexandr A.; Belousov, Vladimir I.; Chirkov, Alexey V.; Denisov, Gregory G.; Korchagin, Vyacheslav V.; Kornishin, Sergey Yu.; Tai, Evgeny M.

2011-06-01

We describe the design and test results of the transmission line for liquid-state (LS) and solid-state (SS) DNP spectrometers with the second-harmonic 258.6 GHz gyrotron at the Institute of the Biophysical Chemistry Center of Goethe University (Frankfurt). The 13-meter line includes a mode converter, HE11 waveguides, 4 mitre bends, a variable polarizer-attenuator, directional couplers, a water-flow calorimeter and a mechanical switch. A microwave power of about 15 W was obtained in the pure HE11 mode at the spectrometer inputs.

First isolate of KPC-2-producing Klebsiella pneumonaie sequence type 23 from the Americas.

PubMed

Cejas, Daniela; Fernández Canigia, Liliana; Rincón Cruz, Giovanna; Elena, Alan X; Maldonado, Ivana; Gutkind, Gabriel O; Radice, Marcela A

2014-09-01

KPC-2-producing Klebsiella pneumoniae isolates mainly correspond to clonal complex 258 (CC258); however, we describe KPC-2-producing K. pneumoniae isolates belonging to invasive sequence type 23 (ST23). KPC-2 has scarcely been reported to occur in ST23, and this report describes the first isolation of this pathogen in the Americas. Acquisition of resistant markers in virulent clones could mark an evolutionary step toward the establishment of these clones as major nosocomial pathogens. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

To amend section 2710 of title 18, United States Code, to clarify that a video tape service provider may obtain a consumer's informed, written consent on an ongoing basis and that consent may be obtained through the Internet.

THOMAS, 112th Congress

Rep. Goodlatte, Bob [R-VA-6

2011-07-08

Senate - 12/20/2012 By Senator Leahy from Committee on the Judiciary filed written report. Report No. 112-258. Additional views filed. (All Actions) Notes: For further action, see H.R.6671, which became Public Law 112-258 on 1/10/2013. Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

Nucleocapsid protein-dependent assembly of the RNA packaging signal of Middle East respiratory syndrome coronavirus.

PubMed

Hsin, Wei-Chen; Chang, Chan-Hua; Chang, Chi-You; Peng, Wei-Hao; Chien, Chung-Liang; Chang, Ming-Fu; Chang, Shin C

2018-05-24

Middle East respiratory syndrome coronavirus (MERS-CoV) consists of a positive-sense, single-stranded RNA genome and four structural proteins: the spike, envelope, membrane, and nucleocapsid protein. The assembly of the viral genome into virus particles involves viral structural proteins and is believed to be mediated through recognition of specific sequences and RNA structures of the viral genome. A culture system for the production of MERS coronavirus-like particles (MERS VLPs) was determined and established by electron microscopy and the detection of coexpressed viral structural proteins. Using the VLP system, a 258-nucleotide RNA fragment, which spans nucleotides 19,712 to 19,969 of the MERS-CoV genome (designated PS258(19712-19969) ME ), was identified to function as a packaging signal. Assembly of the RNA packaging signal into MERS VLPs is dependent on the viral nucleocapsid protein. In addition, a 45-nucleotide stable stem-loop substructure of the PS258(19712-19969) ME interacted with both the N-terminal domain and the C-terminal domain of the viral nucleocapsid protein. Furthermore, a functional SARS-CoV RNA packaging signal failed to assemble into the MERS VLPs, which indicated virus-specific assembly of the RNA genome. A MERS-oV RNA packaging signal was identified by the detection of GFP expression following an incubation of MERS VLPs carrying the heterologous mRNA GFP-PS258(19712-19969) ME with virus permissive Huh7 cells. The MERS VLP system could help us in understanding virus infection and morphogenesis.

Effects of a Behavioral and Exercise Program on Depression and Quality of Life in Community-Dwelling Older Adults: A Controlled, Quasi-Experimental Study.

PubMed

Azizan, Azilyana; Justine, Maria

2016-02-01

Sedentary behavior and low participation in exercise among older adults can lead to depression and low quality of life (QOL). The current study investigated the effects of behavioral and exercise programs on depression severity and QOL among Malaysian community-dwelling older adults. A controlled, quasi-experimental, pre-posttest design was used. A total of 63 participants were divided into three groups: (a) exercise and behavior group (EBG), (b) exercise only group (EG), and (c) control group (CG). Results showed a significant difference in depression among groups (F(2,58) = 33.49, p < 0.01, η(2) = 0.54; mean, EBG < EG < CG) and in physical (F(2,58) = 5.33, p < 0.01, η(2)= 0.16; mean, EBG > EG > CG) and mental (F(2,58) = 4.08, p < 0.01, η(2) = 0.12; mean, EBG > CG > EG) scores of QOL. A combination of behavioral and exercise programs has superior effects on depression and QOL of older adults. [Journal of Gerontological Nursing, 42(2), 45-54.]. Copyright 2016, SLACK Incorporated.

The C-terminal domain of connexin43 modulates cartilage structure via chondrocyte phenotypic changes

PubMed Central

Gago-Fuentes, Raquel; Bechberger, John F.; Varela-Eirin, Marta; Varela-Vazquez, Adrian; Acea, Benigno; Fonseca, Eduardo

2016-01-01

Chondrocytes in cartilage and bone cells population express connexin43 (Cx43) and gap junction intercellular communication (GJIC) is essential to synchronize cells for coordinated electrical, mechanical, metabolic and chemical communication in both tissues. Reduced Cx43 connectivity decreases chondrocyte differentiation and defective Cx43 causes skeletal defects. The carboxy terminal domain (CTD) of Cx43 is located in the cytoplasmic side and is key for protein functions. Here we demonstrated that chondrocytes from the CTD-deficient mice, K258stop/Cx43KO and K258stop/K258stop, have reduced GJIC, increased rates of proliferation and reduced expression of collagen type II and proteoglycans. We observed that CTD-truncated mice were significantly smaller in size. Together these results demonstrated that the deletion of the CTD negatively impacts cartilage structure and normal chondrocyte phenotype. These findings suggest that the proteolytic cleavage of the CTD under pathological conditions, such as under the activation of metalloproteinases during tissue injury or inflammation, may account for the deleterious effects of Cx43 in cartilage and bone disorders such as osteoarthritis. PMID:27682878

40 CFR 466.33 - New source performance standards.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 6.13 0.79 Oil and grease 97.24 12.60 97.24 12.60 TSS 145.86 18.91 116.69 15.12 pH (1) (1) (1) (1... 0.03 0.18 0.20 Nickel 1.10 0.14 0.74 0.10 Zinc 2.03 0.27 0.84 0.11 Aluminum 6.03 0.78 2.47 0.32 Iron 2.45 0.32 1.26 0.16 Oil and grease 19.92 2.58 19.92 2.58 TSS 29.88 3.87 23.90 3.10 pH (1) (1) (1) (1...

40 CFR 466.33 - New source performance standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 6.13 0.79 Oil and grease 97.24 12.60 97.24 12.60 TSS 145.86 18.91 116.69 15.12 pH (1) (1) (1) (1... 0.03 0.18 0.20 Nickel 1.10 0.14 0.74 0.10 Zinc 2.03 0.27 0.84 0.11 Aluminum 6.03 0.78 2.47 0.32 Iron 2.45 0.32 1.26 0.16 Oil and grease 19.92 2.58 19.92 2.58 TSS 29.88 3.87 23.90 3.10 pH (1) (1) (1) (1...

40 CFR 466.33 - New source performance standards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 6.13 0.79 Oil and grease 97.24 12.60 97.24 12.60 TSS 145.86 18.91 116.69 15.12 pH (1) (1) (1) (1... 0.03 0.18 0.20 Nickel 1.10 0.14 0.74 0.10 Zinc 2.03 0.27 0.84 0.11 Aluminum 6.03 0.78 2.47 0.32 Iron 2.45 0.32 1.26 0.16 Oil and grease 19.92 2.58 19.92 2.58 TSS 29.88 3.87 23.90 3.10 pH (1) (1) (1) (1...

Children and Youth Camp Safety Act, 1978. Hearing Before the Subcommittee on Child and Human Development of the Committee on Human Resources, United States Senate, 95th Congress, 2nd Session on S. 258--To Provide for the Development and Implementation of Programs for Children and Youth Camp Safety (March 21, 1978).

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. Senate Committee on Human Resources.

The product of some 10 years of work directed toward federal legislation addressing and defining youth camp safety, the Youth Camp Safety Act (S. 258), as presented in these hearings, calls for the federal government to assume a role in the development of state health and safety standards for children attending youth camps in any state in the…

Apparatus for Study of Ion-Thruster Propellant Ionization

DTIC Science & Technology

2006-12-01

extracted . Releasing these electrons can be done in several ways. Thermionic photo emission and field emissions are valid options. All the...50.9 80.7 106 159 208 503]; %% pressure in millitorr P2=P2/1000; %% pressure in torr Vb2 =[296 276 248 258 258 274 324]; %% voltage in volts pd2=d2...262 276 348]; %% voltage in volts pd3=d3*P3; figure(1) plot(pd1,Vb1,’bo-’,’linewidth’,2) hold on plot(pd2, Vb2 ,’rs:’,’linewidth’,2) hold on 42

Multiple animal studies for medical chemical defense program in soldier/patient decontamination and drug development. Task order 85-10. Final report, 1 December 1984-1 April 1987

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joiner, R.L.; Harroff, H.H.; Snider, H.

1987-12-04

A rabbit model has been developed and validated for screening noninvasive candidate decontamination systems for their efficacies against topical exposure to the organophosphage chemical surety materiel (CSM), GD, polymer-thickened GD (TGD), and VX. CSM was applied to rabbits in groups of 8 on their clipped dorsa over a range of doses. Dose sites were decontaminated beginning 2 minutes after exposure with both components of the M258A1 standard field kit in the recommended sequence. Replicate LD50s were calculated for each CSM with probit analyses of the doses and lethality rates from replicate studies. A composite LD50 was calculated from the datamore » pooled across replicates for each CSM. The composite LD50 was validated for each CSM by comparing the lethality rate obtained in three replicates of 8 animals each with the population mean of 50 percent. The LD50 values obtained for the three CSM tested produced valid mortality ratios when compared to the population mean. Thus the screen is ready to test candidate decontamination systems. The screen compares the lethality rate obtained from 8 animals each dosed at the established M258A1 LD50 and decontaminated according to the manufacturer's instructions with a candidate system against the population mean of 50 percent. An M258A1-decontaminated control group of 8 animals is included to check for drift via a control chart method. Any candidate decontamination system that is as effective as or more effective than the dual-component M258A1 standard passes the screen and is a candidate for further testing.« less

Prognostic value of mutational characteristics in gastrointestinal stromal tumors: a single-center experience in 275 cases.

PubMed

Wang, Ming; Xu, Jia; Zhao, Wenyi; Tu, Lin; Qiu, Weiqing; Wang, Chaojie; Shen, Yangyin; Liu, Qiang; Cao, Hui

2014-01-01

The objective of this study was to investigate the impact of KIT/PDGFRA mutations on the prognosis of gastrointestinal stromal tumors (GISTs). In the present study, genotype analyses were performed based on GIST samples from 275 patients. The relationship between mutation and clinicopathological characteristics were explored. All factors were evaluated for their impacts on relapse-free survival (RFS). Briefly, the results of genotype analyses showed that mutations were identified in 258 (93.8 %) patients, and deletion was the most frequent type of mutation accounting for 47.3 % (122/258) of all mutation cases, followed by substitution (87/258, 33.7 %) and duplication (49/258, 19.0 %). Moreover, for KIT exon 11 mutation, the most frequently involved area was from codon 557 to 560. Deep analyses showed that the mutation types were correlated with tumor location (P = 0.005), tumor size (P = 0.022), mitosis rate (P < 0.001), risk grade (P < 0.001), and relapse (P = 0.004). Furthermore, delW557-K558 correlated with mitosis rate (P = 0.042) and relapse (P = 0.036), and delTyr568/570 correlated with tumor origin (P = 0.018). Most importantly, mitotic rate [HR = 2.901 (95 % CI 1.094-7.695), P = 0.032] and risk grade [HR = 9.629 (95 % CI 1.997-46.416), P = 0.005] would be the representative traditional prognostic factors, and deletion with >3 codons would be an novel independent predictor of poor outcome for RFS in GIST patients with deletion mutation of KIT exon 11 [HR = 7.970 (95 % CI 1.774-35.803), P = 0.007]. All results indicated that mutation determined clinicopathological features and prognosis of GISTs, and more than three codons involvement may be a novel adverse indicator.

Active Participation of Cellular Chaperone Hsp90 in Regulating the Function of Rotavirus Nonstructural Protein 3 (NSP3)*

PubMed Central

Dutta, Dipanjan; Chattopadhyay, Shiladitya; Bagchi, Parikshit; Halder, Umesh Chandra; Nandi, Satabdi; Mukherjee, Anupam; Kobayashi, Nobumichi; Taniguchi, Koki; Chawla-Sarkar, Mamta

2011-01-01

Heat shock protein 90 (Hsp90) has been reported to positively regulate rotavirus replication by modulating virus induced PI3K/Akt and NFκB activation. Here, we report the active association of Hsp90 in the folding and stabilization of rotavirus nonstructural protein 3 (NSP3). In pCD-NSP3-transfected cells, treatment with Hsp90 inhibitor (17-N,N-dimethylethylenediamine-geldanamycin (17DMAG)) resulted in the proteasomal degradation of NSP3. Sequence analysis and deletion mutations revealed that the region spanning amino acids 225–258 within the C-terminal eIF4G-binding domain of NSP3 is a putative Hsp90 binding region. Co-immunoprecipitation and mammalian two-hybrid experiments revealed direct interaction of the C-terminal 12-kDa domain of Hsp90 (C90) with residues 225–258 of NSP3. NSP3-Hsp90 interaction is important for the formation of functionally active mature NSP3, because full-length NSP3 in the presence of the Hsp90 inhibitor or NSP3 lacking the amino acid 225–258 region did not show NSP3 dimers following in vitro coupled transcription-translation followed by chase. Disruption of residues 225–258 within NSP3 also resulted in poor RNA binding and eIF4G binding activity. In addition, inhibition of Hsp90 by 17DMAG resulted in reduced nuclear translocation of poly(A)-binding protein and translation of viral proteins. These results highlight the crucial role of Hsp90 chaperone in the regulation of assembly and functionality of a viral protein during the virus replication and propagation in host cells. PMID:21489987

Uncertainty analysis of depth predictions from seismic reflection data using Bayesian statistics

NASA Astrophysics Data System (ADS)

Michelioudakis, Dimitrios G.; Hobbs, Richard W.; Caiado, Camila C. S.

2018-06-01

Estimating the depths of target horizons from seismic reflection data is an important task in exploration geophysics. To constrain these depths we need a reliable and accurate velocity model. Here, we build an optimum 2-D seismic reflection data processing flow focused on pre-stack deghosting filters and velocity model building and apply Bayesian methods, including Gaussian process emulation and Bayesian History Matching, to estimate the uncertainties of the depths of key horizons near the Deep Sea Drilling Project (DSDP) borehole 258 (DSDP-258) located in the Mentelle Basin, southwest of Australia, and compare the results with the drilled core from that well. Following this strategy, the tie between the modelled and observed depths from DSDP-258 core was in accordance with the ±2σ posterior credibility intervals and predictions for depths to key horizons were made for the two new drill sites, adjacent to the existing borehole of the area. The probabilistic analysis allowed us to generate multiple realizations of pre-stack depth migrated images, these can be directly used to better constrain interpretation and identify potential risk at drill sites. The method will be applied to constrain the drilling targets for the upcoming International Ocean Discovery Program, leg 369.

Radio observations of a few selected blazars

NASA Technical Reports Server (NTRS)

Saikia, D. J.; Salter, C. J.; Neff, S. G.; Gower, A. C.; Sinha, R. P.

1987-01-01

The paper presents total-intensity and linear-polarization observations of four selected blazars, 0716+714, 0752+258, 1156+295 and 1400+162, with the VLA A-array, and MERLIN and EVN observations of 1400+162. The sources 0752+258 and 1400+162 which have nearly constant optical polarization, have well-defined double-lobed radio structure, with relatively weak radio cores, and are likely to be at large viewing angles. In addition, 0752+258 appears to be a twin-jet blazar. The position angle (PA) of the VLBI jet in 1400+162 is close to that of the arcsec-scale jet near the nucleus, as well as the optical and 2-cm core polarization PAs. The blazars 0716+714 and 1156+295, which exhibit strongly variable optical polarization, have a core-dominated radio structure and perhaps have their jet axes close to the line-of-sight. From polarization observations at 20, 18, 6, and 2 cm, it is found that the rotation measure of the radio core in 0716+714 is about -20 rad/sq m. It is suggested that low values of core rotation measure in core-dominated sources could be consistent with the relativistic beaming models.

The arsenic hyperaccumulating Pteris vittata expresses two arsenate reductases

NASA Astrophysics Data System (ADS)

Cesaro, Patrizia; Cattaneo, Chiara; Bona, Elisa; Berta, Graziella; Cavaletto, Maria

2015-09-01

Enzymatic reduction of arsenate to arsenite is the first known step in arsenate metabolism in all organisms. Although the presence of one mRNA arsenate reductase (PvACR2) has been characterized in gametophytes of P. vittata, no arsenate reductase protein has been directly observed in this arsenic hyperaccumulating fern, yet. In order to assess the possible presence of arsenate reductase in P. vittata, two recombinant proteins, ACR2-His6 and Trx-His6-S-Pv2.5-8 were prepared in Escherichia coli, purified and used to produce polyclonal antibodies. The presence of these two enzymes was evaluated by qRT-PCR, immunoblotting and direct MS analysis. Enzymatic activity was detected in crude extracts. For the first time we detected and identified two arsenate reductase proteins (PvACR2 and Pv2.5-8) in sporophytes and gametophytes of P. vittata. Despite an increase of the mRNA levels for both proteins in roots, no difference was observed at the protein level after arsenic treatment. Overall, our data demonstrate the constitutive protein expression of PvACR2 and Pv2.5-8 in P. vittata tissues and propose their specific role in the complex metabolic network of arsenic reduction.

Effect of urea and urea-gamma treatments on cellulose degradation of Thai rice straw and corn stalk

NASA Astrophysics Data System (ADS)

Banchorndhevakul, Siriwattana

2002-08-01

Cellulose degradation of 20% urea treated and 20% urea-10 kGy gamma treated Thai rice straw and corn stalk showed that combination effect of urea and gamma radiation gave a higher % decrease in neutral detergent fiber (NDF), acid detergent fiber (ADF), acid detergent lignin (ADL), cellulose, hemicellulose, and lignin and cutin in comparison with urea effect only for both room temperature storage and room temperature +258 K storage. The results also indicated that cellulose degradation proceeded with time, even at 258 K. A drastic drop to less than half of the original contents in NDF, ADF, and ADL could not be obtained in this study.

Lithographic microfabrication of biocompatible polymers for tissue engineering and lab-on-a-chip applications

NASA Astrophysics Data System (ADS)

Balciunas, Evaldas; Jonusauskas, Linas; Valuckas, Vytautas; Baltriukiene, Daiva; Bukelskiene, Virginija; Gadonas, Roaldas; Malinauskas, Mangirdas

2012-06-01

In this work, a combination of Direct Laser Writing (DLW), PoliDiMethylSiloxane (PDMS) soft lithography and UV lithography was used to create cm- scale microstructured polymer scaolds for cell culture experiments out of dierent biocompatible materials: novel hybrid organic-inorganic SZ2080, PDMS elastomer, biodegradable PEG- DA-258 and SU-8. Rabbit muscle-derived stem cells were seeded on the fabricated dierent periodicity scaolds to evaluate if the relief surface had any eect on cell proliferation. An array of microlenses was fabricated using DLW out of SZ2080 and replicated in PDMS and PEG-DA-258, showing good potential applicability of the used techniques in many other elds like micro- and nano- uidics, photonics, and MicroElectroMechanical Systems (MEMS). The synergetic employment of three dierent fabrication techniques allowed to produce desired objects with low cost, high throughput and precision as well as use materials that are dicult to process by other means (PDMS and PEG-DA-258). DLW is a relatively slow fabrication method, since the object has to be written point-by-point. By applying PDMS soft lithography, we were enabled to replicate laser-fabricated scaolds for stem cell growth and micro-optical elements for lab-on-a-chip applications with high speed, low cost and good reproducible quality.

L x-ray production cross sections in Th and U at 17.8, 25.8 and 46.9 keV photon energies

NASA Astrophysics Data System (ADS)

Kumar, Ajay; Puri, Sanjiv; Shahi, J. S.; Garg, M. L.; Mehta, D.; Singh, Nirmal

2001-02-01

The L x-ray production (XRP) differential cross sections in Th and U have been measured at the 17.8 keV incident photon energy (E_L3

40 CFR 258.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

...; fertilizer/agricultural chemicals; food and related products/by-products; inorganic chemicals; iron and steel manufacturing; leather and leather products; nonferrous metals manufacturing/foundries; organic chemicals...

A preoperative low cancer antigen 125 level (≤25.8 mg/dl) is a useful criterion to determine the optimal timing of interval debulking surgery following neoadjuvant chemotherapy in epithelial ovarian cancer.

PubMed

Morimoto, Akemi; Nagao, Shoji; Kogiku, Ai; Yamamoto, Kasumi; Miwa, Maiko; Wakahashi, Senn; Ichida, Kotaro; Sudo, Tamotsu; Yamaguchi, Satoshi; Fujiwara, Kiyoshi

2016-06-01

The purpose of this study is to investigate the clinical characteristics to determine the optimal timing of interval debulking surgery following neoadjuvant chemotherapy in patients with advanced epithelial ovarian cancer. We reviewed the charts of women with advanced epithelial ovarian cancer, fallopian tube cancer or primary peritoneal cancer who underwent interval debulking surgery following neoadjuvant chemotherapy at our cancer center from April 2006 to April 2014. There were 139 patients, including 91 with ovarian cancer [International Federation of Gynecology and Obstetrics (FIGO) Stage IIIc in 56 and IV in 35], two with fallopian tube cancers (FIGO Stage IV, both) and 46 with primary peritoneal cancer (FIGO Stage IIIc in 27 and IV in 19). After 3-6 cycles (median, 4 cycles) of platinum-based chemotherapy, interval debulking surgery was performed. Sixty-seven patients (48.2%) achieved complete resection of all macroscopic disease, while 72 did not. More patients with cancer antigen 125 levels ≤25.8 mg/dl at pre-interval debulking surgery achieved complete resection than those with higher cancer antigen 125 levels (84.7 vs. 21.3%; P< 0.0001). Patients with no ascites at pre-interval debulking surgery also achieved a higher complete resection rate (63.5 vs. 34.1%; P< 0.0001). Moreover, most patients (86.7%) with cancer antigen 125 levels ≤25.8 mg/dl and no ascites at pre-interval debulking surgery achieved complete resection. A low cancer antigen 125 level of ≤25.8 mg/dl and the absence of ascites at pre-interval debulking surgery are major predictive factors for complete resection during interval debulking surgery and present useful criteria to determine the optimal timing of interval debulking surgery. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Report: landfill alternative daily cover: conserving air space and reducing landfill operating cost.

PubMed

Haughey, R D

2001-02-01

Title 40, Part 258 of the Code of Federal Regulations, Solid Waste Disposal Facility Criteria, commonly referred to as Subtitle D, became effective on October 9, 1993. It establishes minimum criteria for solid waste disposal facility siting, design, operations, groundwater monitoring and corrective action, and closure and postclosure maintenance, while providing EPA-approved state solid waste regulatory programs flexibility in implementing the criteria. Section 258.21(a) [40 CFR 258.21(a)] requires owners or operators of municipal solid waste landfill (MSWLF) units to cover disposed solid waste with 30cm of earthen material at the end of the operating day, or at more frequent intervals, if necessary, to control disease vectors, fires, odours, blowing litter, and scavenging. This requirement is consistent with already existing solid waste facility regulations in many states. For many MSWLFs, applying daily cover requires the importation of soil which increases landfill operating costs. Daily cover also uses valuable landfill air space, reducing potential operating revenue and the landfill's operating life. 40 CFR 258.21 (b) allows the director of an approved state to approve alternative materials of an alternative thickness if the owner or operator demonstrates that the alternative material and thickness will control disease vectors, fires, odours, blowing litter, and scavenging without presenting a threat to human health and the environment. Many different types of alternative daily cover (ADC) are currently being used, including geosynthetic tarps, foams, garden waste, and auto shredder fluff. These materials use less air space than soil and can reduce operating costs. This paper discusses the variety of ADCs currently being used around the country and their applicability to different climates and operating conditions, highlighting the more unusual types of ADC, the types of demonstrations necessary to obtain approval of ADC, and the impact on landfill air space and operating costs of ADC use.

40 CFR 25.8 - Responsiveness summaries.

Code of Federal Regulations, 2010 CFR

2010-07-01

... required.) Responsiveness summaries shall be forwarded to the appropriate decision-making official and... request such evaluations from any advisory group and provide an opportunity for other participating...

Migration and habitats of diadromous Danube River sturgeons in Romania: 1998-2000

USGS Publications Warehouse

Kynard, B.; Suciu, R.; Horgan, M.

2002-01-01

Upstream migrant adults of stellate sturgeon, Acipenser stellatus (10 in 1998, 43 in 1999) and Russian sturgeon, A. gueldenstaedtii (three in 1999) were captured at river km (rkm) 58-137, mostly in the spring, and tagged with acoustic tags offering a reward for return. The overharvest was revealed by tag returns (38% in 1998, 28% in 1999) and by harvest within 26 days (and before reaching spawning grounds) of the six stellate sturgeon tracked upstream. A drop-back of > 50% of the tagged sturgeon, some to the Black Sea, shows a high sensitivity to interruption of migration and capture/handling/holding. Harvesting and dropback prevented tracking of sturgeon to spawning sites. Gillnetting and tracking of stellate sturgeon showed that the autumn migration ended in early October (river temperature 16??C) and identified a likely wintering area at river km (rkm) 75-76 (St George Branch). Thus, fishery harvesting after early October captures wintering fish, not migrants. Rare shoreline cliffs in the lower river likely create the only rocky habitat for sturgeon spawning. A survey for potential spawning habitats found five sites with rocky substrate and moderate water velocity, all ???rkm 258. Drift netting caught early life-stages of 17 fish species and one sturgeon, a beluga, Huso huso, larva likely spawned at ???rkm 258. All diadromous Danube sturgeons likely spawn at ???rkm 258.

4 CFR 25.8 - Alcoholic beverages and narcotics.

Code of Federal Regulations, 2014 CFR

2014-01-01

... alcoholic beverages, narcotic drugs, hallucinogens, marijuana, barbiturates, or amphetamines is prohibited..., marijuana, barbiturate, or amphetamine. This prohibition shall not apply in cases where the drug is being...

4 CFR 25.8 - Alcoholic beverages and narcotics.

Code of Federal Regulations, 2011 CFR

2011-01-01

... alcoholic beverages, narcotic drugs, hallucinogens, marijuana, barbiturates, or amphetamines is prohibited..., marijuana, barbiturate, or amphetamine. This prohibition shall not apply in cases where the drug is being...

4 CFR 25.8 - Alcoholic beverages and narcotics.

Code of Federal Regulations, 2012 CFR

2012-01-01

... alcoholic beverages, narcotic drugs, hallucinogens, marijuana, barbiturates, or amphetamines is prohibited..., marijuana, barbiturate, or amphetamine. This prohibition shall not apply in cases where the drug is being...

4 CFR 25.8 - Alcoholic beverages and narcotics.

Code of Federal Regulations, 2010 CFR

2010-01-01

... alcoholic beverages, narcotic drugs, hallucinogens, marijuana, barbiturates, or amphetamines is prohibited..., marijuana, barbiturate, or amphetamine. This prohibition shall not apply in cases where the drug is being...

4 CFR 25.8 - Alcoholic beverages and narcotics.

Code of Federal Regulations, 2013 CFR

2013-01-01

... alcoholic beverages, narcotic drugs, hallucinogens, marijuana, barbiturates, or amphetamines is prohibited..., marijuana, barbiturate, or amphetamine. This prohibition shall not apply in cases where the drug is being...

20 CFR 258.1 - Hearings.

Code of Federal Regulations, 2010 CFR

2010-04-01

... production of records and documents, administer oaths, take testimony, make all pertinent investigations and findings of fact, and render decisions upon such findings. (b) Where the Board determines that an oral...

24 CFR 207.258a - Title requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... MULTIFAMILY HOUSING MORTGAGE INSURANCE Contract Rights and Obligations Rights and Duties of Mortgagee Under... the mortgage was filed for record, with the exception of such liens or other matters affecting the...

Head Trauma: First Aid

MedlinePlus

... id=258&terms=cpr. Accessed Oct. 8, 2014. Traumatic brain injury. The Merck Manual Professional Edition. http://www.merckmanuals.com/professional/injuries_poisoning/traumatic_brain_injury_tbi/traumatic_brain_injury.html. Accessed Oct. 8, ...

Observations of black hole candidate GRS 1758-258 by the GRATIS balloon-borne telescope and other observatories

NASA Astrophysics Data System (ADS)

Keck, John William

2001-08-01

The Gamma Ray Arcminute Telescope Imaging System (GRATIS) was flown from Alice Springs, Australia on October 17-18, 1995. The experiment consists of 35 individual one-dimensional coded-aperture telescopes with a field of view of 40 arcminutes in the imaging direction. We review the basic design of GRATIS, concentrating on the electronics critical to data acquisition. We survey the origins and types of background radiation that contaminate the data of GRATIS. We review previous work attempting to characterize the atmospheric gamma-ray background and combine the most dependable experimental results to model it. We calculate approximate magnitudes for all background components, and give the results of Monte Carlo simulations of the cosmic diffuse and atmospheric components using the COG radiation transport package. Finally, we combine GRATIS data with previously published and archival data from GRANAT, ROSAT, CGRO, RXTE, BeppoSAX, ASCA, and the VLA to produce a long-term multi-wavelength light curve of Galactic black hole candidate GRS 1758-258. In light of divergent analyses of the 1991-1993 ROSAT observations, we have re-analyzed these data; we find the soft x-rays track the hard x-rays, and that the fits require no black-body component-indicating that GRS 1758-258 did not go to the high state in 1993. We offer two standard corona-disk interpretations of the emission and an interpretation based on the ADAF model for a system with m˙ <~ m˙crit. We find the 1990-1993 co-eval hard and soft observations support the ADAF predictions. We discuss a new way to constrain black-hole mass with spectral data and the ADAF theory, and apply this technique to GRS 1758-258 to find MBH >~ 8-9 Msolar at an assumed distance of 8.5 kpc. Further investigations of the ADAF model allow us to critically evaluate the model against the data and flux- flux diagram of Barret, McClintock, & Grindlay (1996) and to understand the limits of the latter's ``X-ray burster box.''

Veterans Health and Benefits Improvement Act of 2013

THOMAS, 113th Congress

Sen. Sanders, Bernard [I-VT

2013-05-14

Senate - 12/09/2013 Placed on Senate Legislative Calendar under General Orders. Calendar No. 258. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

40 CFR 258.53 - Ground-water sampling and analysis requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... include consistent sampling and analysis procedures that are designed to ensure monitoring results that... testing period. If a multiple comparisons procedure is used, the Type I experiment wise error rate for...

Gulf of Mexico

Atmospheric Science Data Center

2014-05-15

article title:  Unique Views of Gulf Oil Slick     View Larger Image ... image. The red symbol indicates the former location of the drilling platform. The image dimensions are 346 by 258 kilometers (215 by 160 ...

40 CFR 258.61 - Post-closure care requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... the final cover; (2) Maintaining and operating the leachate collection system in accordance with the... stop managing leachate if the owner or operator demonstrates that leachate no longer poses a threat to...

40 CFR 258.61 - Post-closure care requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... the final cover; (2) Maintaining and operating the leachate collection system in accordance with the... stop managing leachate if the owner or operator demonstrates that leachate no longer poses a threat to...

40 CFR 258.61 - Post-closure care requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... the final cover; (2) Maintaining and operating the leachate collection system in accordance with the... stop managing leachate if the owner or operator demonstrates that leachate no longer poses a threat to...

40 CFR 258.61 - Post-closure care requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... the final cover; (2) Maintaining and operating the leachate collection system in accordance with the... stop managing leachate if the owner or operator demonstrates that leachate no longer poses a threat to...

40 CFR 258.13 - Fault areas.

Code of Federal Regulations, 2013 CFR

2013-07-01

... expansions shall not be located within 200 feet (60 meters) of a fault that has had displacement in Holocene... have been displaced with respect to that on the other side. (2) Displacement means the relative...

40 CFR 258.13 - Fault areas.

Code of Federal Regulations, 2011 CFR

2011-07-01

... expansions shall not be located within 200 feet (60 meters) of a fault that has had displacement in Holocene... have been displaced with respect to that on the other side. (2) Displacement means the relative...

40 CFR 258.13 - Fault areas.

Code of Federal Regulations, 2014 CFR

2014-07-01

... expansions shall not be located within 200 feet (60 meters) of a fault that has had displacement in Holocene... have been displaced with respect to that on the other side. (2) Displacement means the relative...

40 CFR 258.13 - Fault areas.

Code of Federal Regulations, 2012 CFR

2012-07-01

... expansions shall not be located within 200 feet (60 meters) of a fault that has had displacement in Holocene... have been displaced with respect to that on the other side. (2) Displacement means the relative...

40 CFR 258.13 - Fault areas.

Code of Federal Regulations, 2010 CFR

2010-07-01

... expansions shall not be located within 200 feet (60 meters) of a fault that has had displacement in Holocene... have been displaced with respect to that on the other side. (2) Displacement means the relative...

24 CFR 207.258 - Insurance claim requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... in 24 CFR part 200, subpart B, of its intention to file an insurance claim and of its election either..., ledger cards, documents, books, papers, and accounts relating to the mortgage transaction. (iv) All...

5. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, 1936 NORTH ELEVATION (REAR). - Mision Nuestra Senora del Socorro, Moon Road at Farm Road 258, Socorro, El Paso County, TX

8. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, 1936 NAVE (SOUTH ELEVATION). - Mision Nuestra Senora del Socorro, Moon Road at Farm Road 258, Socorro, El Paso County, TX

1. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, 1936 SOUTH ELEVATION (FRONT). - Mision Nuestra Senora del Socorro, Moon Road at Farm Road 258, Socorro, El Paso County, TX

9. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, 1936 NAVE (SOUTH ELEVATION). - Mision Nuestra Senora del Socorro, Moon Road at Farm Road 258, Socorro, El Paso County, TX

24 CFR 251.3 - Case-by-case conversion to full insurance.

Code of Federal Regulations, 2010 CFR

2010-04-01

... AUTHORITIES COINSURANCE FOR THE CONSTRUCTION OR SUBSTANTIAL REHABILITATION OF MULTIFAMILY HOUSING PROJECTS... written notice under 24 CFR 207.258 of its intent to file an insurance claim upon the Commissioner's...

24 CFR 251.3 - Case-by-case conversion to full insurance.

Code of Federal Regulations, 2012 CFR

2012-04-01

... AUTHORITIES COINSURANCE FOR THE CONSTRUCTION OR SUBSTANTIAL REHABILITATION OF MULTIFAMILY HOUSING PROJECTS... written notice under 24 CFR 207.258 of its intent to file an insurance claim upon the Commissioner's...

24 CFR 251.3 - Case-by-case conversion to full insurance.

Code of Federal Regulations, 2014 CFR

2014-04-01

... AUTHORITIES COINSURANCE FOR THE CONSTRUCTION OR SUBSTANTIAL REHABILITATION OF MULTIFAMILY HOUSING PROJECTS... written notice under 24 CFR 207.258 of its intent to file an insurance claim upon the Commissioner's...

8 CFR 335.2 - Examination of applicant.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Investigation that two properly prepared fingerprint cards (Form FD-258) have been determined unclassifiable for... and to conduct such cross-examination as may be required for a full and true disclosure of the facts...

8 CFR 335.2 - Examination of applicant.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Investigation that two properly prepared fingerprint cards (Form FD-258) have been determined unclassifiable for... and to conduct such cross-examination as may be required for a full and true disclosure of the facts...

14 CFR 1274.928 - Foreign national employee investigative requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... completed applicant fingerprint card (Federal Bureau of Investigation Card FD-258) for each foreign national... facilities. The NASA Form 531 and fingerprint card may be obtained from the NASA Installation Security Office...

14 CFR 1274.928 - Foreign national employee investigative requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

... completed applicant fingerprint card (Federal Bureau of Investigation Card FD-258) for each foreign national... facilities. The NASA Form 531 and fingerprint card may be obtained from the NASA Installation Security Office...

14 CFR 1274.928 - Foreign national employee investigative requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... completed applicant fingerprint card (Federal Bureau of Investigation Card FD-258) for each foreign national... facilities. The NASA Form 531 and fingerprint card may be obtained from the NASA Installation Security Office...

14 CFR 1274.928 - Foreign national employee investigative requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... completed applicant fingerprint card (Federal Bureau of Investigation Card FD-258) for each foreign national... facilities. The NASA Form 531 and fingerprint card may be obtained from the NASA Installation Security Office...

40 CFR Appendix I to Part 258 - Constituents for Detection Monitoring

Code of Federal Regulations, 2013 CFR

2013-07-01

...) Cobalt (Total) (8) Copper (Total) (9) Lead (Total) (10) Nickel (Total) (11) Selenium (Total) (12) Silver (Total) (13) Thallium (Total) (14) Vanadium (Total) (15) Zinc (Total) Organic Constituents: (16) Acetone...

40 CFR Appendix I to Part 258 - Constituents for Detection Monitoring

Code of Federal Regulations, 2014 CFR

2014-07-01

...) Cobalt (Total) (8) Copper (Total) (9) Lead (Total) (10) Nickel (Total) (11) Selenium (Total) (12) Silver (Total) (13) Thallium (Total) (14) Vanadium (Total) (15) Zinc (Total) Organic Constituents: (16) Acetone...

Effects of cardiorespiratory fitness and weight status on knowledge of physical activity and fitness, attitude toward physical education, and physical activity.

PubMed

Chen, Senlin; Gu, Xiangli

2018-02-20

The purpose of this study was to examine the effects of cardiorespiratory fitness and weight status on knowledge of physical activity and fitness (PAF knowledge), attitude toward physical education (PE), and physical activity. A total of 343 middle school students participated in the study (Age: M/SD = 12.76/.94, ranging from 11 to 14 years old). PE Metrics™ was used to measure PAF knowledge, and Attitude toward Physical Education Questionnaire and Youth Activity Profile were used to measure attitude, physical activity and sedentary behavior. Fitness and weight status were assessed using FitnessGram and converted to in Healthy Fitness Zone (HFZ) or Not in HFZ. Two-way multivariate analyses of covariance (MANCOVA; gender and grade as covariates) showed a significant group effect for cardiorespiratory fitness (Λ Pilla  = .07, F 4,255  = 5.03, p = .001, [Formula: see text] = .07) but not for weight status (p = .57). PAF knowledge (F 1,258  = 9.49, p < .01, [Formula: see text]= .04), attitude (F 1,258  = 4.45, p < .05, [Formula: see text]= .02) and sedentary behavior (F 1,258  = 6.89, p < .01, [Formula: see text]= .03) all favored the HFZ group. The findings reinforce the importance of promoting cardiorespiratory fitness in middle school PE as students acquire attitude, knowledge, and behaviors needed for active-living.

Synthesis of rutherfordium isotopes in the 238U(26Mg, xn)264-xRf reaction and study of their decay properties

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gates, Jacklyn M; Gates, J.M.; Garcia, M.A.

2008-01-15

Isotopes of rutherfordium (258-261Rf) were produced in irradiations of 238U targets with 26Mg beams. Excitation functions were measured for the 4n, 5n and 6n exit channels. Production of 261Rf in the 3n exit channel with a cross section of 28+92-26 pb was observed. Alpha decay of 258Rf was observed for the first time with an alpha-particle energy of 9.05+-0.03 MeV and an alpha/total decay branching ratio of 0.31+-0.11. In 259Rf, the electron capture/total decay branching ratio was measured to be 0.15+-0.04. The measured half-lives for 258Rf, 259Rf and 260Rf were 14.7+1.2-1.0 ms, 2.5+0.4-0.3 s and 22.2+3.0-2.4 ms, respectively, in agreementmore » with literature data. The systematics of the alpha decay Q values and of the partial spontaneous fission half-lives were evaluated for even-even nuclides in the region of the N = 152, Z = 100 deformed shell. The influence of the N = 152 shell on the alpha decay Q values for rutherfordium was observed to be similar to that of the lighter elements (96<_ Z<_ 102). However, the N = 152 shell does not stabilize the rutherfordium isotopes against spontaneous fission, as it does in the lighter elements (96<_ Z<_102).« less

40 CFR 258.21 - Cover material requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... scavenging without presenting a threat to human health and the environment. (c) The Director of an approved... conditions; and (3) Be protective of human health and the environment. [56 FR 51016, Oct. 9, 1991, as amended...

40 CFR 258.21 - Cover material requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... scavenging without presenting a threat to human health and the environment. (c) The Director of an approved... conditions; and (3) Be protective of human health and the environment. [56 FR 51016, Oct. 9, 1991, as amended...

40 CFR 258.21 - Cover material requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... scavenging without presenting a threat to human health and the environment. (c) The Director of an approved... conditions; and (3) Be protective of human health and the environment. [56 FR 51016, Oct. 9, 1991, as amended...

Mysteries of icosahedral quasicrystals: how are the atoms arranged?

PubMed

Ishimasa, Tsutomu

2016-07-01

Higher-dimensional structure analysis of quasicrystals is now possible. Yamada et al. [IUCrJ (2016), 3, 247-258] have solved the atomic structure of icosahedral ScZn7.33 including the characteristic imperfections.

7. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, 1936 NAVE AND ALTAR (NORTH ELEVATION). - Mision Nuestra Senora del Socorro, Moon Road at Farm Road 258, Socorro, El Paso County, TX

2. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, 1936 DETAIL OF ENTRANCE (SOUTH ELEVATION). - Mision Nuestra Senora del Socorro, Moon Road at Farm Road 258, Socorro, El Paso County, TX

14 CFR § 1274.928 - Foreign national employee investigative requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... completed applicant fingerprint card (Federal Bureau of Investigation Card FD-258) for each foreign national... facilities. The NASA Form 531 and fingerprint card may be obtained from the NASA Installation Security Office...

40 CFR Appendix I to Part 258 - Constituents for Detection Monitoring

Code of Federal Regulations, 2012 CFR

2012-07-01

...) (8) Copper (Total) (9) Lead (Total) (10) Nickel (Total) (11) Selenium (Total) (12) Silver (Total) (13) Thallium (Total) (14) Vanadium (Total) (15) Zinc (Total) Organic Constituents: (16) Acetone 67-64-1 (17...

40 CFR 258.40 - Design criteria.

Code of Federal Regulations, 2013 CFR

2013-07-01

... component must consist of at least a two-foot layer of compacted soil with a hydraulic conductivity of no... compacted soil com-ponent. (c) When approving a design that complies with paragraph (a)(1) of this section...

40 CFR 258.40 - Design criteria.

Code of Federal Regulations, 2014 CFR

2014-07-01

... component must consist of at least a two-foot layer of compacted soil with a hydraulic conductivity of no... compacted soil com-ponent. (c) When approving a design that complies with paragraph (a)(1) of this section...

40 CFR 258.40 - Design criteria.

Code of Federal Regulations, 2011 CFR

2011-07-01

... component must consist of at least a two-foot layer of compacted soil with a hydraulic conductivity of no... compacted soil com-ponent. (c) When approving a design that complies with paragraph (a)(1) of this section...

40 CFR 258.40 - Design criteria.

Code of Federal Regulations, 2010 CFR

2010-07-01

... component must consist of at least a two-foot layer of compacted soil with a hydraulic conductivity of no... compacted soil com-ponent. (c) When approving a design that complies with paragraph (a)(1) of this section...

40 CFR 258.40 - Design criteria.

Code of Federal Regulations, 2012 CFR

2012-07-01

... component must consist of at least a two-foot layer of compacted soil with a hydraulic conductivity of no... compacted soil com-ponent. (c) When approving a design that complies with paragraph (a)(1) of this section...

30 CFR 206.258 - Washing allowances-general.

Code of Federal Regulations, 2010 CFR

2010-07-01

... value determined pursuant to § 206.257 of this subpart was based upon like-quality unwashed coal. Under... value for royalty purposes to zero. (b) If MMS determines that a lessee has improperly determined a...

30 CFR 1206.258 - Washing allowances-general.

Code of Federal Regulations, 2011 CFR

2011-07-01

... wash coal, unless the value determined pursuant to § 1206.257 of this subpart was based upon like... allowance reduce the value for royalty purposes to zero. (b) If ONRR determines that a lessee has improperly...

8 CFR 258.1 - Limitations-General.

Code of Federal Regulations, 2010 CFR

2010-01-01

... vessel is made fast or let go, in the United States or the coastal waters thereof. (1) Longshore work is... geographic area, either on a seacoast, lake, river, or other navigable body of water, which contains one or...

3. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, 1936 NORTH ELEVATION OF FRONT PORTION (EAST END). - Mision Nuestra Senora del Socorro, Moon Road at Farm Road 258, Socorro, El Paso County, TX

4. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Historic American Buildings Survey, Marvin Eickenroht, Photographer May 25, 1936 SOUTHEAST ELEVATION OF REAR PORTION (EAST SIDE). - Mision Nuestra Senora del Socorro, Moon Road at Farm Road 258, Socorro, El Paso County, TX

8 CFR 299.1 - Prescribed forms.

Code of Federal Regulations, 2011 CFR

2011-01-01

...-94 Application for Suspension of Deportation. FD-258 12-29-82 Applicant Fingerprint Card. G-28 10-25... Immigration and Nationality Act (Term or Single Entry). I-312 04-15-76 Designation of Attorney in Fact. I-320B...

Microscopic Phase-Space Exploration Modeling of ^{258}Fm Spontaneous Fission.

PubMed

Tanimura, Yusuke; Lacroix, Denis; Ayik, Sakir

2017-04-14

We show that the total kinetic energy (TKE) of nuclei after the spontaneous fission of ^{258}Fm can be well reproduced using simple assumptions on the quantum collective phase space explored by the nucleus after passing the fission barrier. Assuming energy conservation and phase-space exploration according to the stochastic mean-field approach, a set of initial densities is generated. Each density is then evolved in time using the nuclear time-dependent density-functional theory with pairing. This approach goes beyond the mean-field theory by allowing spontaneous symmetry breaking as well as a wider dynamical phase-space exploration leading to larger fluctuations in collective space. The total kinetic energy and mass distributions are calculated. New information on the fission process: fluctuations in scission time, strong correlation between TKE and collective deformation, as well as prescission particle emission, are obtained. We conclude that fluctuations of the TKE and mass are triggered by quantum fluctuations.

L X-ray fluorescence cross sections of some rare earth elements ( Z = 62, 64, 66, 68 and 70) at 17.8, 22.6 and 25.8 keV

NASA Astrophysics Data System (ADS)

Mandal, A. C.; Santra, S.; Mitra, D.; Sarkar, M.; Bhattacharya, D.

2005-06-01

L X-ray fluorescence cross sections of the elements with Z = 62, 64, 66, 68 and 70 have been measured at 17.8, 22.6 and 25.8 keV using an X-ray tube and secondary exciters of Mo, Ag and Sn. The measured cross sections have been compared with the theoretical predictions and with the data of others. Theoretical values calculated using photoionisation cross sections from Scofield [Lawrence Livermore Laboratory, UCRL-51326, 1973], fluorescence yields and Coster-Kronig transition probabilities from Puri et al. [X-ray Spectrom. 22 (1993) 358] and radiative widths from Campbell and Wang [At. Data Nucl. Data Tables 43 (1989) 281] show good agreement with our data. Except two sets of data on Lγ cross sections, all the data of other groups agree well with those of ours.

Gas Exchange of Algae

PubMed Central

Ammann, Elizabeth C. B.; Lynch, Victoria H.

1966-01-01

Changes in the oxygen partial pressure of air over the range of 8 to 258 mm of Hg did not adversely affect the photosynthetic capacity of Chlorella pyrenoidosa. Gas exchange and growth measurements remained constant for 3-week periods and were similar to air controls (oxygen pressure of 160 mm of Hg). Oxygen partial pressures of 532 and 745 mm of Hg had an adverse effect on algal metabolism. Carbon dioxide consumption was 24% lower in the gas mixture containing oxygen at a pressure 532 mm of Hg than in the air control, and the growth rate was slightly reduced. Oxygen at a partial pressure of 745 mm of Hg decreased the photosynthetic rate 39% and the growth rate 37% over the corresponding rates in air. The lowered metabolic rates remained constant during 14 days of measurements, and the effect was reversible after this time. Substitution of helium or argon for the nitrogen in air had no effect on oxygen production, carbon dioxide consumption, or growth rate for 3-week periods. All measurements were made at a total pressure of 760 mm of Hg, and all gas mixtures were enriched with 2% carbon dioxide. Thus, the physiological functioning and reliability of a photosynthetic gas exchanger should not be adversely affected by: (i) oxygen partial pressures ranging from 8 to 258 mm of Hg; (ii) the use of pure oxygen at reduced total pressure (155 to 258 mm of Hg) unless pressure per se affects photosynthesis, or (iii) the inclusion of helium or argon in the gas environment (up to a partial pressure of 595 mm of Hg). PMID:5927028

Accretion States of the Galactic Micro Quasar GRS 1758-258

NASA Technical Reports Server (NTRS)

Soria, Roberto; Mehdipour, Missagh; Broderick, Jess W.; Hao, JingFang; Hannikainen, Diana C.; Pottschmidt, Katja; Zhang, Shuang-Nan

2011-01-01

We present the results of a radio and X-ray study of the Galactic micro quasar GRS 1758-258, using unpublished archival data and new observations. We focus in particular on the 2000-2002 state transitions, and on its more quiet behaviour in 2008-2009. Our spectral and timing analysis of the XMM-Newton data shows that the source was in the canonical intermediate, soft and hard states in 2000 September 19,2001 March 22 and 2002 September 28, respectively. We estimate the disk size, luminosity and temperature, which are consistent with a black hole mass approx.10 Solar Mass, There is much overlap between the range of total X-ray luminosities (on average approx. 0.02L(sub Edd)) in the hard and soft states, and probably between the corresponding mass accretion rates; in fact, the hard state is often more luminous. The extended radio lobes seen in 1992 and 1997 are still present in 2008-2009. The 5-GHz radio core flux density has shown variability between approx. 0.1-0.5 mJy over the last two decades. This firmly places GRS 1758-258 in the radio-quiet sequence of Galactic black holes, in the radio/X-ray plane. We note that this dichotomy is similar to the dichotomy between the radio/X-ray sequences of Seyfert and radio galaxies. We propose that the different radio efficiency of the two sequences is due to relativistic electron/positron jets in radio-loud black holes, and sub-relativistic, thermally dominated outflows in radio-quiet sources.

2012 Survey of Active Duty Spouses: Tabulations of Responses

DTIC Science & Technology

2013-09-30

246 j. Attending religious/ spiritual services ................................................... 248 k. Accepting stressful...258 p. Participating in religious/ spiritual activities .......................................... 260 q. Defining the family...life .............................................................. 276 57. Seeking Spiritual Support: Constructed from Q57j, p, and s. Subfactor of

MONITORING GUIDANCE FOR BIOREACTOR LANDFILLS

EPA Science Inventory

Experimental bioreactor landfill operations at operating Municipal Solid Waste (MSW) landfills can be approved under the research development and demonstration (RD&D) provisions of 30CFR 258.4. To provide a basis for consistent data collection for future decision-making in suppor...

MONITORING APPROACHES FOR BIOREACTOR LANDFILLS

EPA Science Inventory

Experimental bioreactor landfill operations at operating Municipal Solid Waste (MSW) landfills can be approved under the research development and demonstration (RD&D) provisions of 40 CFR 258.4. To provide a basis for consistent data collection for future decision-making in suppo...

2004 Wisconsin traffic crash facts

DOT National Transportation Integrated Search

2005-07-01

2004 Facts and Figures - 784 persons were killed in Wisconsin motor vehicle traffic crashes. This is an average of two lives lost each day on Wisconsin trafficways. - 55,258 persons were injured in 38,451 reported injury crashes and 714 fatal crashes...

40 CFR 258.4 - Research, development, and demonstration permits.

Code of Federal Regulations, 2012 CFR

2012-07-01

... leachate collection system designed and constructed to maintain less than a 30-cm depth of leachate on the..., or cause leachate depth on the liner to exceed 30-cm. (c) Any permit issued under this section must...

40 CFR 258.4 - Research, development, and demonstration permits.

Code of Federal Regulations, 2013 CFR

2013-07-01

... leachate collection system designed and constructed to maintain less than a 30-cm depth of leachate on the..., or cause leachate depth on the liner to exceed 30-cm. (c) Any permit issued under this section must...

40 CFR 258.4 - Research, development, and demonstration permits.

Code of Federal Regulations, 2014 CFR

2014-07-01

... leachate collection system designed and constructed to maintain less than a 30-cm depth of leachate on the..., or cause leachate depth on the liner to exceed 30-cm. (c) Any permit issued under this section must...

40 CFR 258.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

...; plastics and resins manufacturing; pulp and paper industry; rubber and miscellaneous plastic products... wastewater treatment plant, water supply treatment plant, or air pollution control facility exclusive of the... a wastewater treatment plant, water supply treatment plant, or air pollution control facility and...

Pseudomonas fluorescens-like bacteria from the stomach: a microbiological and molecular study.

PubMed

Patel, Saurabh Kumar; Pratap, Chandra Bhan; Verma, Ajay Kumar; Jain, Ashok Kumar; Dixit, Vinod Kumar; Nath, Gopal

2013-02-21

To characterize oxidase- and urease-producing bacterial isolates, grown aerobically, that originated from antral biopsies of patients suffering from acid peptic diseases. A total of 258 antral biopsy specimens were subjected to isolation of bacteria followed by tests for oxidase and urease production, acid tolerance and aerobic growth. The selected isolates were further characterized by molecular techniques viz. amplifications for 16S rRNA using universal eubacterial and HSP60 gene specific primers. The amplicons were subjected to restriction analysis and partial sequencing. A phylogenetic tree was generated using unweighted pair group method with arithmetic mean (UPGMA) from evolutionary distance computed with bootstrap test of phylogeny. Assessment of acidity tolerance of bacteria isolated from antrum was performed using hydrochloric acid from 10(-7) mol/L to 10(-1) mol/L. Of the 258 antral biopsy specimens collected from patients, 179 (69.4%) were positive for urease production by rapid urease test and 31% (80/258) yielded typical Helicobacter pylori (H. pylori) after 5-7 d of incubation under a microaerophilic environment. A total of 240 (93%) antral biopsies yielded homogeneous semi-translucent and small colonies after overnight incubation. The partial 16S rRNA sequences revealed that the isolates had 99% similarity with Pseudomonas species. A phylogenetic tree on the basis of 16S rRNA sequences denoted that JQ927226 and JQ927227 were likely to be related to Pseudomonas fluorescens (P. fluorescens). On the basis of HSP60 sequences applied to the UPGMA phylogenetic tree, it was observed that isolated strains in an aerobic environment were likely to be P. fluorescens, and HSP60 sequences had more discriminatory potential rather than 16S rRNA sequences. Interestingly, this bacterium was acid tolerant for hours at low pH. Further, a total of 250 (96.9%) genomic DNA samples of 258 biopsy specimens and DNA from 240 bacterial isolates were positive for the 613 bp amplicons by targeting P. fluorescens-specific conserved putative outer membrane protein gene sequences. This study indicates that bacterial isolates from antral biopsies grown aerobically were P. fluorescens, and thus acid-tolerant bacteria other than H. pylori can also colonize the stomach and may be implicated in pathogenesis/protection.

The effect of sub-zero temperature on the formation and composition of secondary organic aerosol from ozonolysis of alpha-pinene.

PubMed

Kristensen, K; Jensen, L N; Glasius, M; Bilde, M

2017-10-18

This study presents a newly constructed temperature controlled cold-room smog chamber at Aarhus University, Denmark. The chamber is herein utilized to study the effect of sub-zero temperature on the formation and chemical composition of secondary organic aerosol (SOA) from ozone initiated oxidation of α-pinene. The chemical composition of α-pinene SOA formed from dark ozonolysis of α-pinene at 293 K and 258 K was investigated using High-Resolution Time-of-Flight Aerosol Mass Spectrometry (HR-ToF-AMS) and Ultra-High Performance Liquid Chromatography/Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry (UHPLC/ESI-qToF-MS). For comparison, an OH-initiated oxidation experiment was performed at 293 K. In ozonolysis experiments it was found that oxygen-to-carbon (O : C) ratios were higher in the particles formed at 293 K compared to 258 K. A total of 16 different organic acids and 30 dimers esters were quantified in the collected particles composing up to 34% of the total α-pinene SOA mass with increased mass fraction of carboxylic acids in particles from α-pinene ozonolysis at 258 K compared to 293 K. In contrast, dimer esters showed suppressed formation at the sub-zero reaction temperature, thus contributing 3% to SOA mass at 258 K while contributing 9% at 293 K. SOA formed in the OH-initiated oxidation of α-pinene at 293 K resulted in low concentrations of dimer esters supporting Criegee intermediates as a possible pathway to dimer ester formation. Vapour pressure estimates of the identified carboxylic acids and dimer esters are presented and show how otherwise semi-volatile carboxylic acids at sufficiently low temperatures may classify as low or even extremely low volatile organic compounds (ELVOC), thus may add to an enhanced particle formation observed at the sub-zero temperature through gas-to-particle conversion. The change in chemical composition of the SOA particles with temperature is ascribed to a combination of effects: the decreased vapour pressures and hence increased condensation of carboxylic acids from the gas phase to the particle phase along with suppressed formation of the high molecular weight dimer esters and different gas and particle phase chemistry results in particles of different chemical composition as a consequence of low reaction temperatures.

Impact of Clinical Decision Support on Radiography for Acute Ankle Injuries: A Randomized Trial

PubMed Central

Tajmir, Shahein; Raja, Ali S.; Ip, Ivan K.; Andruchow, James; Silveira, Patricia; Smith, Stacy; Khorasani, Ramin

2017-01-01

Introduction While only 15–20% of patients with foot and ankle injuries presenting to urgent care centers have clinically significant fractures, most undergo radiography. We examined the impact of electronic point-of-care clinical decision support (CDS) on adherence to the Ottawa Ankle Rules (OAR), as well as use and yield of foot and ankle radiographs in patients with acute ankle injury. Methods We obtained institutional review board approval for this randomized controlled study performed April 18, 2012—December 15, 2013. All ordering providers credentialed at an urgent care affiliated with a quaternary care academic hospital were randomized to either receive or not receive CDS, based on the OAR and integrated into the physician order-entry system, with feedback at the time of imaging order. If the patient met OAR low-risk criteria, providers were advised against imaging and could either cancel the order or ignore the alert. We identified patients with foot and ankle complaints via ICD-9 billing codes and electronic health records and radiology reports reviewed for those who were eligible. Chi-square was used to compare adherence to the OAR (primary outcome), radiography utilization rate and radiography yield of foot and ankle imaging (secondary outcomes) between the intervention and control groups. Results Of 14,642 patients seen at urgent care during the study period, 613 (4.2%, representing 632 visits) presented with acute ankle injury and were eligible for application of the OAR; 374 (59.2%) of these were seen by control-group providers. In the intervention group, CDS adherence was higher for both ankle (239/258=92.6% vs. 231/374=61.8%, p=0.02) and foot radiography (209/258=81.0% vs. 238/374=63.6%; p<0.01). However, ankle radiography use was higher in the intervention group (166/258=64.3% vs. 183/374=48.9%; p<0.01), while foot radiography use (141/258=54.6% vs. 202/374=54.0%; p=0.95) was not. Radiography yield was also higher in the intervention group (26/307=8.5% vs. 18/385=4.7%; p=0.04). Conclusion Clinical decision support, previously demonstrated to improve guideline adherence for high-cost imaging, can also improve guideline adherence for radiography – as demonstrated by increased OAR adherence and increased imaging yield. PMID:28435501

37 CFR 258.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... establishment used for commercial purposes, such as bars, restaurants, private offices, fitness clubs, oil rigs... multi-unit permanent or temporary dwelling where private home viewing occurs, such as hotels, dormitories, hospitals, apartments, condominiums and prisons, all of which shall be subject to the rates...

37 CFR 258.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... establishment used for commercial purposes, such as bars, restaurants, private offices, fitness clubs, oil rigs... multi-unit permanent or temporary dwelling where private home viewing occurs, such as hotels, dormitories, hospitals, apartments, condominiums and prisons, all of which shall be subject to the rates...

37 CFR 258.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... establishment used for commercial purposes, such as bars, restaurants, private offices, fitness clubs, oil rigs... multi-unit permanent or temporary dwelling where private home viewing occurs, such as hotels, dormitories, hospitals, apartments, condominiums and prisons, all of which shall be subject to the rates...

MONITORING APPROACHES FOR BIOREACTOR LANDFILLS - Report

EPA Science Inventory

Experimental bioreactor landfill operations at operating Municipal Solid Waste (MSW) landfills can be approved under the research development and demonstration (RD&D) provisions of 30CFR 258.4. To provide a basis for consistent data collection for future decision-making in suppor...

Young Children's Mathematics References during Free Play in Family Childcare Settings

ERIC Educational Resources Information Center

Hendershot, Shawnee M.; Berghout Austin, Ann M.; Blevins-Knabe, Belinda; Ota, Carrie

2016-01-01

Very little is known about children's discussion of mathematics topics during unstructured play. Ginsburg, Lin, Ness, and Seo [2003. Young American and Chinese children's everyday mathematical activity. Mathematical Thinking and Learning, 5(4), 235-258. Retrieved from…

40 CFR 258.26 - Run-on/run-off control systems.

Code of Federal Regulations, 2014 CFR

2014-07-01

... storm; (2) A run-off control system from the active portion of the landfill to collect and control at least the water volume resulting from a 24-hour, 25-year storm. (b) Run-off from the active portion of...

40 CFR 258.26 - Run-on/run-off control systems.

Code of Federal Regulations, 2013 CFR

2013-07-01

... storm; (2) A run-off control system from the active portion of the landfill to collect and control at least the water volume resulting from a 24-hour, 25-year storm. (b) Run-off from the active portion of...

40 CFR 258.26 - Run-on/run-off control systems.

Code of Federal Regulations, 2012 CFR

2012-07-01

... storm; (2) A run-off control system from the active portion of the landfill to collect and control at least the water volume resulting from a 24-hour, 25-year storm. (b) Run-off from the active portion of...

20 CFR 655.520 - Special provisions regarding automated vessels.

Code of Federal Regulations, 2012 CFR

2012-04-01

... automated vessels. (ii) Prevailing practice after Secretary of State determination of non-reciprocity. Section 258(d) of the Act provides a reciprocity exception (separate from the prevailing practice..., this reciprocity exception becomes nonapplicable where the Secretary of State determines that, for a...

20 CFR 655.520 - Special provisions regarding automated vessels.

Code of Federal Regulations, 2014 CFR

2014-04-01

... automated vessels. (ii) Prevailing practice after Secretary of State determination of non-reciprocity. Section 258(d) of the Act provides a reciprocity exception (separate from the prevailing practice..., this reciprocity exception becomes nonapplicable where the Secretary of State determines that, for a...

20 CFR 655.520 - Special provisions regarding automated vessels.

Code of Federal Regulations, 2010 CFR

2010-04-01

... automated vessels. (ii) Prevailing practice after Secretary of State determination of non-reciprocity. Section 258(d) of the Act provides a reciprocity exception (separate from the prevailing practice..., this reciprocity exception becomes nonapplicable where the Secretary of State determines that, for a...

20 CFR 655.520 - Special provisions regarding automated vessels.

Code of Federal Regulations, 2013 CFR

2013-04-01

... automated vessels. (ii) Prevailing practice after Secretary of State determination of non-reciprocity. Section 258(d) of the Act provides a reciprocity exception (separate from the prevailing practice..., this reciprocity exception becomes nonapplicable where the Secretary of State determines that, for a...

20 CFR 655.520 - Special provisions regarding automated vessels.

Code of Federal Regulations, 2011 CFR

2011-04-01

... automated vessels. (ii) Prevailing practice after Secretary of State determination of non-reciprocity. Section 258(d) of the Act provides a reciprocity exception (separate from the prevailing practice..., this reciprocity exception becomes nonapplicable where the Secretary of State determines that, for a...

37 CFR 258.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

...” means an establishment used for commercial purposes, such as bars, restaurants, private offices, fitness... establishment” shall not include a multi-unit permanent or temporary dwelling where private home viewing occurs, such as hotels, dormitories, hospitals, apartments, condominiums and prisons, all of which shall be...

7 CFR 51.306 - Tolerances.

Code of Federal Regulations, 2013 CFR

2013-01-01

... inches or 65 grams 63 grams 21/4 inches or 75 grams 70 grams 23/8 inches or 84 grams 82 grams 21/2 inches or 100 grams 95 grams 25/8 inches or 115 grams 109 grams 23/4 inches or 139 grams 134 grams...

7 CFR 51.306 - Tolerances.

Code of Federal Regulations, 2014 CFR

2014-01-01

... inches or 65 grams 63 grams 21/4 inches or 75 grams 70 grams 23/8 inches or 84 grams 82 grams 21/2 inches or 100 grams 95 grams 25/8 inches or 115 grams 109 grams 23/4 inches or 139 grams 134 grams...

17 CFR Appendix A to Part 31 - Schedule of Fees for Registration of Leverage Commodities

Code of Federal Regulations, 2011 CFR

2011-04-01

... orders should be sent to the attention of the Office of the Secretariat, Commodity Futures Trading...), Independent Offices Appropriation Act of 1952, as amended by Pub. L. 97-258, 96 Stat. 1051 (Sept. 13, 1982...

17 CFR Appendix A to Part 31 - Schedule of Fees for Registration of Leverage Commodities

Code of Federal Regulations, 2010 CFR

2010-04-01

... orders should be sent to the attention of the Office of the Secretariat, Commodity Futures Trading...), Independent Offices Appropriation Act of 1952, as amended by Pub. L. 97-258, 96 Stat. 1051 (Sept. 13, 1982...

Hazardous Waste Cleanup: IBM Corporation in Kingston, New York

EPA Pesticide Factsheets

This site, approximately 258 acres in size, is located at Neighborhood Road in Kingston, New York. The site was first developed in the 1950s. Activities in the past were the development, manufacture, and testing of computer systems and the manufacture of

Victimization and Suicidality among Female College Students

ERIC Educational Resources Information Center

Leone, Janel M.; Carroll, James M.

2016-01-01

Objective: To investigate the predictive role of victimization in suicidality among college women. Participants: Female respondents to the American College Health Association National College Health Assessment II (N = 258). Methods: Multivariate logistic regression analyses examined the relationship between victimization and suicidality. Results:…

NDCEE Annual Technologies Publication

DTIC Science & Technology

2004-07-01

LCAAP), Independence, Missouri Lone Star Army Ammunition Plant (LSAAP), Texarkana , Texas Marine Corps Logistics Base, Yermo Annex, Barstow...100-101, 117, 123, 186, 210, 251, 258, 285, 291; 200-312, 337, 339, 852; 800-801; 900- 909, 1956, 1989, 2016, 2017 , 2018, 2019, 2021, 2089, 2097, 2106

77 FR 31017 - Office of Facilities Management and Program Services; Information Collection; Background...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-24

... a Basic National Agency Check Criminal History, GSA Form 176; and 2. Two sets of fingerprints on FBI Fingerprint Cards, for FD-258. This is not a request to collect new information, this is a request to change...

77 FR 37862 - Open-Circuit Self-Contained Breathing Apparatus Remaining Service-Life Indicator Performance...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-25

...; NIOSH-258] Open-Circuit Self-Contained Breathing Apparatus Remaining Service-Life Indicator Performance... open-circuit self-contained breathing apparatus (OC- SCBA) remaining service-life indicators... ``Open-Circuit Self-Contained Breathing Apparatus Remaining Service-Life Indicator Performance...

Dendritic Cell Migration Toward CCL21 Gradient Requires Functional Cx43

PubMed Central

Ruez, Richard; Dubrot, Juan; Zoso, Alice; Bacchetta, Marc; Molica, Filippo; Hugues, Stéphanie; Kwak, Brenda R.; Chanson, Marc

2018-01-01

Dendritic cells (DCs) travel through lymphatic vessels to transport antigens and present them to T cells in lymph nodes. DCs move directionally toward lymphatics by virtue of their CCR7 and a CCL21 chemotactic gradient. We evaluated in vivo and in bone marrow-derived dendritic cells (BMDCs) whether the gap junction protein Cx43 contributes to CCL21/CCR7-dependent DC migration in wild-type (WT) mice, heterozygous (Cx43+/−) mice and mice expressing a truncated form of Cx43 lacking its regulatory C-terminus (Cx43K258/−). In a model of flank skin inflammation, we found that the recruitment of myeloid DCs (mDCs) to skin draining lymph nodes was reduced in Cx43K258/− mice as compared to WT and Cx43+/− mice. In addition, the migration of Cx43K258/− BMDCs toward CCL21 was abolished in an in vitro chemotactic assay while it was only reduced in Cx43+/− cells. Both mutant genotypes showed defects in the directionality of BMDC migration as compared to WT BMDCs. No difference was found between the three populations of BMDCs in terms of expression of surface markers (CD11c, CD86, CD80, CD40, MHC-II, and CCR7) after differentiation and TLR activation. Finally, examination of the CCR7-induced signaling pathways in BMDCs revealed normal receptor-induced mobilization of intracellular Ca2+. These results demonstrate that full expression of an intact Cx43 is critical to the directionality and rate of DC migration, which may be amenable to regulation of the immune response. PMID:29636699

Crystal structure of product-bound complex of UDP-N-acetyl-D-mannosamine dehydrogenase from Pyrococcus horikoshii OT3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pampa, K.J., E-mail: sagarikakj@gmail.com; Lokanath, N.K.; Girish, T.U.

Highlights: • Determined the structure of UDP-D-ManNAcADH to a resolution of 1.55 Å. • First complex structure of PhUDP-D-ManNAcADH with UDP-D-ManMAcA. • The monomeric structure consists of three distinct domains. • Cys258 acting as catalytic nucleophilic and Lys204 acts as acid/base catalyst. • Oligomeric state plays an important role for the catalytic function. - Abstract: UDP-N-acetyl-D-mannosamine dehydrogenase (UDP-D-ManNAcDH) belongs to UDP-glucose/GDP-mannose dehydrogenase family and catalyzes Uridine-diphospho-N-acetyl-D-mannosamine (UDP-D-ManNAc) to Uridine-diphospho-N-acetyl-D-mannosaminuronic acid (UDP-D-ManNAcA) through twofold oxidation of NAD{sup +}. In order to reveal the structural features of the Pyrococcus horikoshii UDP-D-ManNAcADH, we have determined the crystal structure of the product-bound enzyme bymore » X-ray diffraction to resolution of 1.55 Å. The protomer folds into three distinct domains; nucleotide binding domain (NBD), substrate binding domain (SBD) and oligomerization domain (OD, involved in the dimerization). The clear electron density of the UDP-D-ManNAcA is observed and the residues binding are identified for the first time. Crystal structures reveal a tight dimeric polymer chains with product-bound in all the structures. The catalytic residues Cys258 and Lys204 are conserved. The Cys258 acts as catalytic nucleophile and Lys204 as acid/base catalyst. The product is directly interacts with residues Arg211, Thr249, Arg244, Gly255, Arg289, Lys319 and Arg398. In addition, the structural parameters responsible for thermostability and oligomerization of the three dimensional structure are analyzed.« less

Genetic and functional analysis of the gene encoding GAP-43 in schizophrenia.

PubMed

Shen, Yu-Chih; Tsai, Ho-Min; Cheng, Min-Chih; Hsu, Shih-Hsin; Chen, Shih-Fen; Chen, Chia-Hsiang

2012-02-01

In earlier reports, growth-associated protein 43 (GAP-43) has been shown to be critical for initial establishment or reorganization of synaptic connections, a process thought to be disrupted in schizophrenia. Additionally, abnormal GAP-43 expression in different brain regions has been linked to this disorder in postmortem brain studies. In this study, we investigated the involvement of the gene encoding GAP-43 in the susceptibility to schizophrenia. We searched for genetic variants in the promoter region and 3 exons (including both UTR ends) of the GAP-43 gene using direct sequencing in a sample of patients with schizophrenia (n=586) and non-psychotic controls (n=576), both being Han Chinese from Taiwan, and conducted an association and functional study. We identified 11 common polymorphisms in the GAP-43 gene. SNP and haplotype-based analyses displayed no associations with schizophrenia. Additionally, we identified 4 rare variants in 5 out of 586 patients, including 1 variant located at the promoter region (c.-258-4722G>T) and 1 synonymous (V110V) and 2 missense (G150R and P188L) variants located at exon 2. No rare variants were found in the control subjects. The results of the reporter gene assay demonstrated that the regulatory activity of construct containing c.-258-4722T was significantly lower as compared to the wild type construct (c.-258-4722G; p<0.001). In silico analysis also demonstrated the functional relevance of other rare variants. Our study lends support to the hypothesis of multiple rare mutations in schizophrenia, and it provides genetic clues that indicate the involvement of GAP-43 in this disorder. Copyright © 2011 Elsevier B.V. All rights reserved.

Comparative Proteomics of Rubber Latex Revealed Multiple Protein Species of REF/SRPP Family Respond Diversely to Ethylene Stimulation among Different Rubber Tree Clones.

PubMed

Tong, Zheng; Wang, Dan; Sun, Yong; Yang, Qian; Meng, Xueru; Wang, Limin; Feng, Weiqiang; Li, Ling; Wurtele, Eve Syrkin; Wang, Xuchu

2017-05-02

Rubber elongation factor (REF) and small rubber particle protein (SRPP) are two key factors for natural rubber biosynthesis. To further understand the roles of these proteins in rubber formation, six different genes for latex abundant REF or SRPP proteins, including REF 138,175,258 and SRPP 117,204,243 , were characterized from Hevea brasiliensis Reyan (RY) 7-33-97. Sequence analysis showed that REFs have a variable and long N-terminal, whereas SRPPs have a variable and long C-terminal beyond the REF domain, and REF 258 has a β subunit of ATPase in its N-terminal. Through two-dimensional electrophoresis (2-DE), each REF/SRPP protein was separated into multiple protein spots on 2-DE gels, indicating they have multiple protein species. The abundance of REF/SRPP proteins was compared between ethylene and control treatments or among rubber tree clones with different levels of latex productivity by analyzing 2-DE gels. The total abundance of each REF/SRPP protein decreased or changed a little upon ethylene stimulation, whereas the abundance of multiple protein species of the same REF/SRPP changed diversely. Among the three rubber tree clones, the abundance of the protein species also differed significantly. Especially, two protein species of REF 175 or REF 258 were ethylene-responsive only in the high latex productivity clone RY 8-79 instead of in RY 7-33-97 and PR 107. Some individual protein species were positively related to ethylene stimulation and latex productivity. These results suggested that the specific protein species could be more important than others for rubber production and post-translational modifications might play important roles in rubber biosynthesis.

38 CFR 21.258 - Cost limitations on approval of self-employment plans.

Code of Federal Regulations, 2011 CFR

2011-07-01

... approved by the VR&E Officer with jurisdiction. Any self-employment plan with an estimated or actual cost of $25,000 or more must be approved by the Director, VR&E Service. (Authority: 38 U.S.C. 3104) [75 FR...

38 CFR 21.258 - Cost limitations on approval of self-employment plans.

Code of Federal Regulations, 2010 CFR

2010-07-01

... approved by the VR&E Officer with jurisdiction. Any self-employment plan with an estimated or actual cost of $25,000 or more must be approved by the Director, VR&E Service. (Authority: 38 U.S.C. 3104) [75 FR...

20 CFR 655.510 - Employer attestations.

Code of Federal Regulations, 2014 CFR

2014-04-01

... practice after Secretary of State determination of non-reciprocity. Section 258(d) of the Act provides a reciprocity exception (separate from the prevailing practice exception) to the prohibition on performance of longshore work by alien crewmembers in U.S. ports. However, this reciprocity exception becomes nonapplicable...

20 CFR 655.510 - Employer attestations.

Code of Federal Regulations, 2012 CFR

2012-04-01

... practice after Secretary of State determination of non-reciprocity. Section 258(d) of the Act provides a reciprocity exception (separate from the prevailing practice exception) to the prohibition on performance of longshore work by alien crewmembers in U.S. ports. However, this reciprocity exception becomes nonapplicable...

20 CFR 655.510 - Employer attestations.

Code of Federal Regulations, 2011 CFR

2011-04-01

... practice after Secretary of State determination of non-reciprocity. Section 258(d) of the Act provides a reciprocity exception (separate from the prevailing practice exception) to the prohibition on performance of longshore work by alien crewmembers in U.S. ports. However, this reciprocity exception becomes nonapplicable...

20 CFR 655.510 - Employer attestations.

Code of Federal Regulations, 2013 CFR

2013-04-01

... practice after Secretary of State determination of non-reciprocity. Section 258(d) of the Act provides a reciprocity exception (separate from the prevailing practice exception) to the prohibition on performance of longshore work by alien crewmembers in U.S. ports. However, this reciprocity exception becomes nonapplicable...

14 CFR 258.2 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC...: (a) Direct air carriers and foreign air carriers that sell or issue tickets in the United States for... (b) Ticket agents doing business in the United States that sell or issue tickets for scheduled...

14 CFR 258.2 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC...: (a) Direct air carriers and foreign air carriers that sell or issue tickets in the United States for... (b) Ticket agents doing business in the United States that sell or issue tickets for scheduled...

14 CFR 258.2 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC...: (a) Direct air carriers and foreign air carriers that sell or issue tickets in the United States for... (b) Ticket agents doing business in the United States that sell or issue tickets for scheduled...

14 CFR 258.2 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC...: (a) Direct air carriers and foreign air carriers that sell or issue tickets in the United States for... (b) Ticket agents doing business in the United States that sell or issue tickets for scheduled...

14 CFR 258.2 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC...: (a) Direct air carriers and foreign air carriers that sell or issue tickets in the United States for... (b) Ticket agents doing business in the United States that sell or issue tickets for scheduled...

38 CFR 21.258 - Cost limitations on approval of self-employment plans.

Code of Federal Regulations, 2013 CFR

2013-07-01

... approved by the VR&E Officer with jurisdiction. Any self-employment plan with an estimated or actual cost of $25,000 or more must be approved by the Director, VR&E Service. (Authority: 38 U.S.C. 3104) [75 FR...

38 CFR 21.258 - Cost limitations on approval of self-employment plans.

Code of Federal Regulations, 2012 CFR

2012-07-01

... approved by the VR&E Officer with jurisdiction. Any self-employment plan with an estimated or actual cost of $25,000 or more must be approved by the Director, VR&E Service. (Authority: 38 U.S.C. 3104) [75 FR...

38 CFR 21.258 - Cost limitations on approval of self-employment plans.

Code of Federal Regulations, 2014 CFR

2014-07-01

... approved by the VR&E Officer with jurisdiction. Any self-employment plan with an estimated or actual cost of $25,000 or more must be approved by the Director, VR&E Service. (Authority: 38 U.S.C. 3104) [75 FR...

Behavior of rigid and flexible culvert pipes under deep fill.

DOT National Transportation Integrated Search

1977-01-01

Along a section of Interstate 77 in Carroll County, in the mountainous region of southwestern Virginia, it was necessary to construct a fill approximately 258 ft (78 m) deep. The flow of a mountain stream had to be carried through this massive embank...

7 CFR 1944.258 - Professional assessment committee.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF... management or an agency in the community which provides assessment services and conforms to section 802(e)(3... CHSP participants, with respect to race, religion, color, sex, national origin, familial status or type...

Occupational Needs Assessment.

ERIC Educational Resources Information Center

Stewart, Betsy

In order to determine community needs and preferences with regard to vocational education, the Cerritos Community College District surveyed 1,386 Cerritos College students, 896 students in area adult schools, 126 participants in regional occupational programs, and 258 community residents. A 46-item questionnaire focused on: (1) preferences for…

3. CONTEXT VIEW LOOKING NORTHWEST OF BUILDING 259 (NORTH SENTRY ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. CONTEXT VIEW LOOKING NORTHWEST OF BUILDING 259 (NORTH SENTRY POST) IN STORAGE ARE WITH BUILDING 258 (STORAGE IGLOO) IN BACKGROUND. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

Programs and Registrations (ACHE-NUEA), 1975-76.

ERIC Educational Resources Information Center

Barton, William D.; And Others

This annual report (1975-76) presents responses from 258 higher education institutions on the trends in continuing education registration in classes, conference programs, and independent study. (The institutions responding carried membership in the Association for Continuing Higher Education and the National University Extension Association.) The…

28 CFR 25.8 - System safeguards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... justice agency computer site must have adequate physical security to protect against any unauthorized... Index is stored electronically for use in an FBI computer environment. The NICS central computer will... authorized personnel who have identified themselves and their need for access to a system security officer...

28 CFR 25.8 - System safeguards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... justice agency computer site must have adequate physical security to protect against any unauthorized... Index is stored electronically for use in an FBI computer environment. The NICS central computer will... authorized personnel who have identified themselves and their need for access to a system security officer...

28 CFR 25.8 - System safeguards.

Code of Federal Regulations, 2013 CFR

2013-07-01

... justice agency computer site must have adequate physical security to protect against any unauthorized... Index is stored electronically for use in an FBI computer environment. The NICS central computer will... authorized personnel who have identified themselves and their need for access to a system security officer...

28 CFR 25.8 - System safeguards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... justice agency computer site must have adequate physical security to protect against any unauthorized... Index is stored electronically for use in an FBI computer environment. The NICS central computer will... authorized personnel who have identified themselves and their need for access to a system security officer...

28 CFR 25.8 - System safeguards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... justice agency computer site must have adequate physical security to protect against any unauthorized... Index is stored electronically for use in an FBI computer environment. The NICS central computer will... authorized personnel who have identified themselves and their need for access to a system security officer...

76 FR 49509 - Records Schedules; Availability and Request for Comments

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-10

... Agency (N1-258-09-3, 1 item, 1 temporary item). Good Farming Practice Documentation, including producer... reconsideration of adverse good farming practice determinations. 3. Department of Agriculture, Risk Management... materials, legislation files, negotiation files, review files, unfair trade practices files, and...

40 CFR 258.55 - Assessment monitoring program.

Code of Federal Regulations, 2013 CFR

2013-07-01

... upgradient edge of the MSWLF unit and downgradient monitoring well screen (minimum distance of travel); (5... effects during a lifetime. For purposes of this subpart, systemic toxicants include toxic chemicals that cause effects other than cancer or mutation. (ii) [Reserved] (j) In establishing ground-water protection...

40 CFR 258.55 - Assessment monitoring program.

Code of Federal Regulations, 2011 CFR

2011-07-01

... upgradient edge of the MSWLF unit and downgradient monitoring well screen (minimum distance of travel); (5... effects during a lifetime. For purposes of this subpart, systemic toxicants include toxic chemicals that cause effects other than cancer or mutation. (ii) [Reserved] (j) In establishing ground-water protection...

40 CFR 258.55 - Assessment monitoring program.

Code of Federal Regulations, 2012 CFR

2012-07-01

... upgradient edge of the MSWLF unit and downgradient monitoring well screen (minimum distance of travel); (5... effects during a lifetime. For purposes of this subpart, systemic toxicants include toxic chemicals that cause effects other than cancer or mutation. (ii) [Reserved] (j) In establishing ground-water protection...

Emergency Unemployment Compensation Continuation Act

THOMAS, 111th Congress

Rep. McDermott, Jim [D-WA-7

2010-11-17

House - 11/18/2010 On motion to suspend the rules and pass the bill, as amended Failed by the Yeas and Nays: (2/3 required): 258 - 154 (Roll no. 579). (All Actions) Tracker: This bill has the status Failed HouseHere are the steps for Status of Legislation:

40 CFR 258.62 - Approval of site-specific flexibility requests in Indian country.

Code of Federal Regulations, 2012 CFR

2012-07-01

... information on the availability of this material at NARA, call 202-741-6030, or go to: http://www.archives.gov... final cover; and (ii) Achieve re-vegetation rates greater than 50% by the end of the first season and a...

40 CFR 258.62 - Approval of site-specific flexibility requests in Indian country.

Code of Federal Regulations, 2013 CFR

2013-07-01

... information on the availability of this material at NARA, call 202-741-6030, or go to: http://www.archives.gov... final cover; and (ii) Achieve re-vegetation rates greater than 50% by the end of the first season and a...

40 CFR 258.62 - Approval of site-specific flexibility requests in Indian country.

Code of Federal Regulations, 2014 CFR

2014-07-01

... information on the availability of this material at NARA, call 202-741-6030, or go to: http://www.archives.gov... final cover; and (ii) Achieve re-vegetation rates greater than 50% by the end of the first season and a...

Charge distributions of fission fragments of low- and high-energy fission of Fm, No, and Rf isotopes

NASA Astrophysics Data System (ADS)

Paşca, H.; Andreev, A. V.; Adamian, G. G.; Antonenko, N. V.

2018-03-01

The charge (mass) distributions of fission fragments resulting from low- and high-energy fission of the even-even nuclei 254 -260 ,264Fm , 258 -264No , and 262 -266Rf are studied with the statistical scission-point model. The calculated results are compared with the available experimental data. In contrast to the experimental data, the calculated mass distribution for 258Fm (s.f.) is strikingly similar to the experimental one for 257Fm (s.f.). The transformation of the shape of charge distribution with increasing isospin and excitation energy occurs gradually and in a similar fashion like that of the mass distribution, but slower. For 254Fm(i.f.), 257Fm(nt h,f), and 260Fm (s.f.), the unexpected difference (symmetric or asymmetric) between the shapes of charge and mass distributions is predicted for the first time. At some critical excitation energy, the saturation of the symmetric component of charge (mass) yields is demonstrated.

Molecular bases of the ABO blood groups of Indians from the Brazilian Amazon region.

PubMed

Franco, R F; Simões, B P; Guerreiro, J F; Santos, S E; Zago, M A

1994-01-01

Phenotype studies of ABO blood groups in most Amerindian populations revealed the exclusive presence of group O. Since group O is the result of the absence of glycosyltransferase activity, its molecular bases may be heterogeneous. We carried out ABO blood group genotyping by analysis of DNA of 30 Indians from 2 Amazonian tribes (Yanomami and Arara), and compared the findings with other populations (Caucasians and Blacks). Two segments of the glycosyltransferase gene were amplified by PCR and digested with KpnI or AluI to detect deletion or base change at positions 258 and 700, respectively. For all subjects, the gene basis of blood group O is the deletion of a single nucleotide at position 258 of the glycosyltransferase A gene, similar to that observed in Caucasoids and Negroids. DNA sequencing of limited regions of the gene supports this conclusion. This finding does not exclude, however, that a heterogeneity of the O allele may be revealed by a more extensive analysis.

29 CFR 776.30 - Construction performed on temporarily idle facilities.

Code of Federal Regulations, 2010 CFR

2010-07-01

.... Southern Package Corp., 320 U.S. 540; Slover v. Wathen & Co., 140 F. (2d) 258 (C.A. 4); Bodden v. McCormick... Bodden v. McCormick Shipping Corp., 188 F. (2d) 733. 54 Maneja v. Waialua Agricultural Co., 349 U.S. 254...

Problems in Decentralized Decision making and Computation.

DTIC Science & Technology

1984-12-01

systesis being referred to. Findeisen [1982] clarifies this distinction by talking about the "programing" and "execution" phases.) 5. The lower and higher...n ... *iii... -258- Findeisen , W., (1982), "Decentralized and Hierarchical Control Under Consistency or Disagreement of Interest," Automatica, Vol. 18

Amie Sluiter | NREL

Science.gov Websites

biomass analysis methods and is primary author on 11 Laboratory Analytical Procedures, which are ) spectroscopic analysis methods. These methods allow analysts to predict the composition of feedstock and process . Patent No. 6,737,258 (2002) Featured Publications "Improved methods for the determination of drying

Explanations for high levels of infant mortality in Pakistan--a dissenting view.

PubMed

Zaidi, A

1989-01-01

The author critiques a paper by Zeba A. Sathar concerning the relationship between poverty and the infant mortality rate in Pakistan. The focus is on the socioeconomic determinants of fertility decline and policy implications. A reply by Sathar is included (pp. 258-9).

Impact of Stereotypes on Intercultural Communication: A Chinese Perspective

ERIC Educational Resources Information Center

Peng, Shi-Yong

2010-01-01

Using Kuhn and McPartland's approach, 116 Chinese college students were recruited and asked to write as many sentences as possible beginning with "Chinese...," "Americans...," and "Japanese...." The population of sentences consisted of 258 adjectives, of which 96 described Chinese, 53 described Americans, and 109…

Benjamin Research Natural Area: guidebook supplement 36

Treesearch

Reid Schuller; Ron Halvorson

2009-01-01

This guidebook describes Benjamin Research Natural Area, a 258-ha (637-ac) tract originally established to represent an example of the western juniper/Idaho fescue (Juniperus occidentalis/Festuca idahoensis) plant association. Subsequent field surveys indicate the predominant vegetation is best characterized as the western juniper/low sagebrush/...

Latino Adolescents' Academic Motivation: The Role of Siblings

ERIC Educational Resources Information Center

Alfaro, Edna C.; Umana-Taylor, Adriana J.

2010-01-01

Guided by an ecological perspective, two competing models were tested to examine how sibling relationship quality directly predicted or interacted with academic support from siblings to predict Latino adolescents' academic motivation (N = 258). Gender differences were examined utilizing multiple group analysis in structural equation modeling.…

Perceptions of Public Relations Education.

ERIC Educational Resources Information Center

Stacks, Don W.; Botan, Carl; Turk, Judy VanSlyke

1999-01-01

Surveys 258 public-relations educators and practitioners, finding they agree that public-relations education is on track; that systematic assessment is an important feature of public-relations education; and that they agreed on how public-relations education should be structured, and demonstrated a high degree of similarity in their preferences…

40 CFR 258.14 - Seismic impact zones.

Code of Federal Regulations, 2012 CFR

2012-07-01

... horizontal acceleration in lithified earth material for the site. The owner or operator must place the... greater probability that the maximum horizontal acceleration in lithified earth material, expressed as a percentage of the earth's gravitational pull (g), will exceed 0.10g in 250 years. (2) Maximum horizontal...

40 CFR 258.14 - Seismic impact zones.

Code of Federal Regulations, 2014 CFR

2014-07-01

... horizontal acceleration in lithified earth material for the site. The owner or operator must place the... greater probability that the maximum horizontal acceleration in lithified earth material, expressed as a percentage of the earth's gravitational pull (g), will exceed 0.10g in 250 years. (2) Maximum horizontal...

40 CFR 258.14 - Seismic impact zones.

Code of Federal Regulations, 2013 CFR

2013-07-01

... horizontal acceleration in lithified earth material for the site. The owner or operator must place the... greater probability that the maximum horizontal acceleration in lithified earth material, expressed as a percentage of the earth's gravitational pull (g), will exceed 0.10g in 250 years. (2) Maximum horizontal...

7 CFR 1944.258 - Professional assessment committee.

Code of Federal Regulations, 2011 CFR

2011-01-01

... the determination of eligibility, and shall ensure the confidentiality of personal and medical records... required to: (1) Perform a formal assessment of each potential elderly program participant to determine if the individual is frail. To qualify as frail, the PAC must determine if the elderly person is...

78 FR 65978 - Application to Export Electric Energy; Brookfield Energy Marketing Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-04

... DEPARTMENT OF ENERGY [OE Docket No. EA-258-D] Application to Export Electric Energy; Brookfield Energy Marketing Inc. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: Brookfield Energy Marketing Inc. (BEMI) has applied to renew its authority...

Stolen Valor Act of 2013

THOMAS, 113th Congress

Sen. Heller, Dean [R-NV

2013-02-04

Senate - 02/04/2013 Read twice and referred to the Committee on the Judiciary. (All Actions) Notes: For further action, see H.R.258, which became Public Law 113-12 on 6/3/2013. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Modeling Human Performance in Restless Bandits with Particle Filters (Preprint)

DTIC Science & Technology

2009-01-01

respond to changes ( Gallistel , 2001). Here, we use a particle filter approach to finding solutions to the restless bandit problem. Particle...Experimental Psychology: Learning, Memory, and Cognition, 10(2), 258-270. Gallistel , C. R., Mark, T., King, A., & Latham, P. E. (2001). The rat

21 CFR 558.258 - Fenbendazole.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... sows: As in paragraph (e)(2)(i) of this section; for control of clostridial enteritis in suckling pigs... reinfection. Do not use in horses intended for human consumption. 000061 (ii) [Reserved] (5) Zoo and wildlife...

21 CFR 558.258 - Fenbendazole.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... sows: As in paragraph (e)(2)(i) of this section; for control of clostridial enteritis in suckling pigs... reinfection. Do not use in horses intended for human consumption. 000061 (ii) [Reserved] (5) Zoo and wildlife...

21 CFR 558.258 - Fenbendazole.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... sows: As in paragraph (e)(2)(i) of this section; for control of clostridial enteritis in suckling pigs... reinfection. Do not use in horses intended for human consumption. 000061 (ii) [Reserved] (5) Zoo and wildlife...

21 CFR 558.258 - Fenbendazole.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... sows: As in paragraph (e)(2)(i) of this section; for control of clostridial enteritis in suckling pigs... reinfection. Do not use in horses intended for human consumption. 000061 (ii) [Reserved] (5) Zoo and wildlife...

21 CFR 558.258 - Fenbendazole.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... sows: As in paragraph (e)(2)(i) of this section; for control of clostridial enteritis in suckling pigs... reinfection. Do not use in horses intended for human consumption. 000061 (ii) [Reserved] (5) Zoo and wildlife...

A FIELD TEST USING COAL:DRDF BLENDS IN SPREADER STOKER-FIRED BOILERS

EPA Science Inventory

This program was conducted to characterize and demonstrate the technical, economic, and environmental feasibility of combustion densified forms of refuse derived fuel (dRDF) blended with coal in spreader stoker-fired boilers. A total of 258.5 Mg (285 tons) of pelletized 1/2-inch-...

24 CFR 207.258 - Insurance claim requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... by mortgagee. (1) When the mortgagee becomes eligible to receive mortgage insurance benefits pursuant... proceedings. If the laws of the State where the property is located do not permit institution of foreclosure... property and to obtain the income therefrom under the mortgage and the law of the particular jurisdiction...

24 CFR 207.258 - Insurance claim requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... by mortgagee. (1) When the mortgagee becomes eligible to receive mortgage insurance benefits pursuant... proceedings. If the laws of the State where the property is located do not permit institution of foreclosure... property and to obtain the income therefrom under the mortgage and the law of the particular jurisdiction...

24 CFR 207.258 - Insurance claim requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... by mortgagee. (1) When the mortgagee becomes eligible to receive mortgage insurance benefits pursuant... proceedings. If the laws of the State where the property is located do not permit institution of foreclosure... property and to obtain the income therefrom under the mortgage and the law of the particular jurisdiction...

Rape Myth Acceptance, Sexual Trauma History, and Posttraumatic Stress Disorder

ERIC Educational Resources Information Center

Baugher, Shannon N.; Elhai, Jon D.; Monroe, James R.; Gray, Matt J.

2010-01-01

The prediction of false rape-related beliefs (rape myth acceptance [RMA]) was examined using the Illinois Rape Myth Acceptance Scale (Payne, Lonsway, & Fitzgerald, 1999) among a nonclinical sample of 258 male and female college students. Predictor variables included measures of attitudes toward women, gender role identity (GRI), sexual trauma…

40 CFR 445.20 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... LANDFILLS POINT SOURCE CATEGORY RCRA Subtitle D Non-Hazardous Waste Landfill § 445.20 Applicability. Except as provided in § 445.1, this subpart applies to discharges of wastewater from landfills subject to the provisions of 40 CFR part 258, Criteria for Municipal Solid Waste Landfills; and 40 CFR part 257...

40 CFR 60.258 - Reporting and recordkeeping.

Code of Federal Regulations, 2010 CFR

2010-07-01

... thereafter, the owner or operator shall record the measurements of the scrubber pressure loss, water supply... occurrences when the measurements of the scrubber pressure loss, water supply flow rate, or pH of the wet... stabilizer or water purchased for use in the coal preparation and processing plant. (5) Monthly certification...

China Report, Red Flag, Number 10, 16 May 1983

DTIC Science & Technology

1983-07-19

coconuts, peppers, cashew nuts , and tea have all broken previous production records. Last year, income distributed over the whole region reached 258...whole brigade planted 3,200 mu of sugarcane, 320 mu of rubber, 13,700 coconut palms, some betel palms, cashews , and other economic crops. The

40 CFR 258.53 - Ground-water sampling and analysis requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... considering the number of samples in the background data base, the data distribution, and the range of the... the background data base, the data distribution, and the range of the concentration values for each... samples collected to establish ground-water quality data must be consistent with the appropriate...

40 CFR 258.53 - Ground-water sampling and analysis requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... considering the number of samples in the background data base, the data distribution, and the range of the... the background data base, the data distribution, and the range of the concentration values for each... samples collected to establish ground-water quality data must be consistent with the appropriate...

The Differential Effects of Rape Prevention Programming on Attitudes, Behavior, and Knowledge.

ERIC Educational Resources Information Center

Heppner, Mary J.; And Others

1995-01-01

Evaluates whether type of programming differentially affects the processing of rape prevention messages, attitudes, knowledge, behaviors, and stability of change. Participants (n=258) were assigned to a didactic-video program, an interactive drama, or control. Results indicated that the interactive video was most effective in central route…

Erratum.

PubMed

2015-09-01

Correction to: Zampi G, et al. Pitfall in Echocardiography: infective endocarditis or valvular strand? Med Ultrason 2015; 17(2): 256-258. The authors have been made aware of the error that appeared in the name of the second author. The correct name is Amedeo Pergolini: Giordano Zampi, Amedeo Pergolini, Maria Denitza Tinti, Claudio Alessi, Luigi Sommariva.

40 CFR 258.58 - Implementation of the corrective action program.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Take any interim measures necessary to ensure the protection of human health and the environment... drinking water supplies or sensitive ecosystems; (iv) Further degradation of the ground-water that may... situations that may pose threats to human health and the environment. (b) An owner or operator may determine...

Determinants of Teachers' Attitudes towards E- Learning in Tanzanian Higher Learning Institutions

ERIC Educational Resources Information Center

Kisanga, Dalton H.

2016-01-01

This survey research study presents the findings on determinants of teachers' attitudes towards e-learning in Tanzanian higher learning institutions. The study involved 258 teachers from 4 higher learning institutions obtained through stratified, simple random sampling. Questionnaires and documentary review were used in data collection. Data were…

Enhancing ADHD and LD Diagnostic Accuracy Using Career Instruments

ERIC Educational Resources Information Center

Dipeolu, Abiola; Hargrave, Stephanie; Storlie, Cassandra A.

2015-01-01

Individuals diagnosed with mental health disorders may have work-related difficulties that impact functioning in all life domains. With limited research on the integration of career and mental health counseling, authors used a discriminant function analysis to assess the predictability of accurately identifying diagnostic categories among 258…

24 CFR 207.258b - Partial payment of claim.

Code of Federal Regulations, 2013 CFR

2013-04-01

... potentially could serve as, a low- and moderate-income housing resource; (2) The property covered by the... maintaining the low- and moderate-income character of the project. This determination shall be based upon the...) The relief resulting from partial payment, when considered with other resources available to the...

24 CFR 207.258b - Partial payment of claim.

Code of Federal Regulations, 2012 CFR

2012-04-01

... potentially could serve as, a low- and moderate-income housing resource; (2) The property covered by the... maintaining the low- and moderate-income character of the project. This determination shall be based upon the...) The relief resulting from partial payment, when considered with other resources available to the...

24 CFR 207.258b - Partial payment of claim.

Code of Federal Regulations, 2010 CFR

2010-04-01

... potentially could serve as, a low- and moderate-income housing resource; (2) The property covered by the... maintaining the low- and moderate-income character of the project. This determination shall be based upon the...) The relief resulting from partial payment, when considered with other resources available to the...

24 CFR 207.258b - Partial payment of claim.

Code of Federal Regulations, 2011 CFR

2011-04-01

... potentially could serve as, a low- and moderate-income housing resource; (2) The property covered by the... maintaining the low- and moderate-income character of the project. This determination shall be based upon the...) The relief resulting from partial payment, when considered with other resources available to the...

24 CFR 207.258b - Partial payment of claim.

Code of Federal Regulations, 2014 CFR

2014-04-01

... potentially could serve as, a low- and moderate-income housing resource; (2) The property covered by the... maintaining the low- and moderate-income character of the project. This determination shall be based upon the...) The relief resulting from partial payment, when considered with other resources available to the...

77 FR 18651 - Qualifying Urban Areas for the 2010 Census

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-27

...,158 Delhi, LA 2,770 Delhi, NY 2,953 Dell Rapids, SD 3,584 Delphi, IN 3,008 Delphos, OH 7,440 Delta, CO 7,849 Delta, OH 3,158 Delta, UT 3,258 Deming, NM 14,903 Demopolis, AL 6,452 Denison, IA 8,240...

14 CFR 23.1353 - Storage battery design and installation.

Code of Federal Regulations, 2012 CFR

2012-01-01

... take appropriate load shedding action. [Doc. No. 4080, 29 FR 17955, Dec. 18, 1964; 30 FR 258, Jan. 9... any probable charging and discharging condition. No uncontrolled increase in cell temperature may... temperatures and pressures presents no problem. (d) No explosive or toxic gases emitted by any battery in...

Sex-role ideology among self-identified psychotherapists.

PubMed

Harper, D W; Leichner, P P; McCrimmon, E

1985-10-01

Analysis of the sex-role ideology of 1,258 self-identified psychotherapists from nine occupations indicated that: the sample was representative; as a group, self-identified psychotherapists were moderately feminist; there were significant differences among occupations; and results were not due solely to the effects of age or sex distributions among occupations.

Managing Corporate Annual Reports. SPEC Kit 258.

ERIC Educational Resources Information Center

O'Connor, Lisa, Comp.

2000-01-01

The purpose of the survey for this SPEC (Systems and Procedures Exchange Center) Kit was to assess the current print corporate annual report collection practices of ARL (Association of Research Libraries) libraries, describe the effects of these collections, and recommend best practices for preserving these significant historical documents. The…

Sexy versus Strong: What Girls and Women Think of Female Athletes

ERIC Educational Resources Information Center

Daniels, Elizabeth A.

2012-01-01

Little research has investigated girls' and college women's reactions to non-objectified media images of women, including those that depict women in instrumental activities like playing a sport. This study examined open-ended responses to images of performance athletes, sexualized athletes, and sexualized models. Participants were 258 adolescent…

Moving an Expeditionary Force: Three Case Studies in Afghanistan

DTIC Science & Technology

2003-01-01

its individual parts.” 258 Stephen R. Covey, The 7 Habits of Highly Effective People (New York: Simon & Schuster, 1989), 186. 48 anywhere in the world...transcon.htm, accessed 26 January 2003]. Covey, Stephen R. The 7 Habits of Highly Effective People . New York: Simon & Schuster, 1989. Department of

Teaching about Implicit Prejudices and Stereotypes: A Pedagogical Demonstration

ERIC Educational Resources Information Center

Adams, Virgil H., III; Devos, Thierry; Rivera, Luis M.; Smith, Heather; Vega, Luis A.

2014-01-01

Social psychology instructors from five distinct state universities in California examined the effect of incorporating the implicit association test (IAT) in a teaching module on students' perceived knowledge of implicit biases and motivation to control prejudice. Students (N = 258) completed a knowledge survey on prejudice, stereotypes, and…

Specifications and Other Standardization Documents Involving Cellular Plastics (Plastic Foams), Cushioning and Related Materials

DTIC Science & Technology

1976-07-01

FOR MEDICAL MATERIAL REQUIRING CONTROLLED TEMPERATURE RANGES 258 PPP-C-1683(1) 8135 69 10 Oct 73 CUSHIONING MATERIAL, EXPANDED POLYSTYRENE LOOSE FILL...Liquid immersion effect on properties of elastoaeric vulcanizates - 45 Lead deflection characteristics - 264 Loose-fill expanded polystyrene - 25f

Airport and airway trust fund : effects of the trust fund taxes' lapsing on FAA's budget

DOT National Transportation Integrated Search

1996-04-15

The Airport and Airway Trust Fund (Trust Fund) was established by the : Airport and Airway Revenue Act of 1970 (P.L. 91-258) to finance the : Federal Aviation Administration's (FAA) investments in the airport and : airway system. The act further prov...

Airport and Airway Trust Fund: Issues Raised by Proposal To Replace the Airline Ticket Tax

DOT National Transportation Integrated Search

1996-12-05

The Airport and Airway Trust Fund (Trust Fund) was established by the Airport : and Airway Revenue Act of 1970 (P.L. 91-258) to finance the Federal Aviation : Administration's (FAA) investments in the airport and airway system. The act : further prov...

Sedona-Red Rock National Scenic Area Act of 2010

THOMAS, 111th Congress

Rep. Kirkpatrick, Ann [D-AZ-1

2010-03-11

House - 09/23/2010 On motion to suspend the rules and pass the bill, as amended Failed by the Yeas and Nays: (2/3 required): 258 - 160 (Roll no. 538). (All Actions) Tracker: This bill has the status Failed HouseHere are the steps for Status of Legislation:

40 CFR 258.41 - Project XL Bioreactor Landfill Projects.

Code of Federal Regulations, 2012 CFR

2012-07-01

... using the Standard Test Method for Measuring Mass per Unit Area of Geotextiles, ASTM D-5261-92... determined by the Standard Test Method for Laboratory Determination of Water (Moisture) Content of Soil and... with the provisions of the FESOP, during the entire period of leachate recirculation and the post...

40 CFR 258.41 - Project XL Bioreactor Landfill Projects.

Code of Federal Regulations, 2011 CFR

2011-07-01

... using the Standard Test Method for Measuring Mass per Unit Area of Geotextiles, ASTM D-5261-92... determined by the Standard Test Method for Laboratory Determination of Water (Moisture) Content of Soil and... with the provisions of the FESOP, during the entire period of leachate recirculation and the post...

40 CFR 258.41 - Project XL Bioreactor Landfill Projects.

Code of Federal Regulations, 2013 CFR

2013-07-01

... using the Standard Test Method for Measuring Mass per Unit Area of Geotextiles, ASTM D-5261-92... determined by the Standard Test Method for Laboratory Determination of Water (Moisture) Content of Soil and... with the provisions of the FESOP, during the entire period of leachate recirculation and the post...

Supporting Students' Knowledge Transfer in Modeling Activities

ERIC Educational Resources Information Center

Piksööt, Jaanika; Sarapuu, Tago

2014-01-01

This study investigates ways to enhance secondary school students' knowledge transfer in complex science domains by implementing question prompts. Two samples of students applied two web-based models to study molecular genetics--the model of genetic code (n = 258) and translation (n = 245). For each model, the samples were randomly divided into…

Cultural Consumption Patterns in South Africa: An Investigation of the Theory of Cultural Omnivores

ERIC Educational Resources Information Center

Snowball, J. D.; Jamal, M.; Willis, K. G.

2010-01-01

Contrary to Bourdieu's theory ("Distinction: A social critique of the judgment of taste". Cambridge, Massachusetts: Harvard University Press (1984)) that cultural consumption of so-called "high" versus popular culture is determined by socio-economic class, Peterson ("Poetics" 21:243-258, 1992; "Poetics"…

78 FR 29334 - Threat Reduction Advisory Committee; Notice of Federal Advisory Committee Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-20

... DEPARTMENT OF DEFENSE Office of the Secretary Threat Reduction Advisory Committee; Notice of... Defense announces the following Federal advisory committee meeting of the Threat Reduction Advisory..., CO. FOR FURTHER INFORMATION CONTACT: Mr. William Hostyn, DoD, Defense Threat Reduction Agency/J2/5/8R...

77 FR 69807 - Threat Reduction Advisory Committee; Notice of Federal Advisory Committee Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-21

... DEPARTMENT OF DEFENSE Office of the Secretary Threat Reduction Advisory Committee; Notice of... following Federal advisory committee meeting of the Threat Reduction Advisory Committee (hereafter referred... INFORMATION CONTACT: Mr. William Hostyn, DoD, Defense Threat Reduction Agency/J2/5/8R-ACP, 8725 John J...

School-Age Offspring of Adolescent Mothers: Environments and Outcomes.

ERIC Educational Resources Information Center

Barratt, Marguerite Stevenson

1991-01-01

Identified factors contributing to competent parenting by adolescent mothers and optimal outcomes for their school-age children (n=258). Optimal parenting was found to be influenced by background factors as well as factors evolving since birth; in turn these factors and parenting influenced outcomes for children. (ABL)

40 CFR 258.15 - Unstable areas.

Code of Federal Regulations, 2014 CFR

2014-07-01

... determining whether an area is unstable: (1) On-site or local soil conditions that may result in significant... releases from a landfill. Unstable areas can include poor foundation conditions, areas susceptible to mass... conditions means those areas where features exist which indicate that a natural or man-induced event may...

40 CFR 258.15 - Unstable areas.

Code of Federal Regulations, 2013 CFR

2013-07-01

... determining whether an area is unstable: (1) On-site or local soil conditions that may result in significant... releases from a landfill. Unstable areas can include poor foundation conditions, areas susceptible to mass... conditions means those areas where features exist which indicate that a natural or man-induced event may...

40 CFR 258.15 - Unstable areas.

Code of Federal Regulations, 2012 CFR

2012-07-01

... determining whether an area is unstable: (1) On-site or local soil conditions that may result in significant... releases from a landfill. Unstable areas can include poor foundation conditions, areas susceptible to mass... conditions means those areas where features exist which indicate that a natural or man-induced event may...

Contrasting Viewpoints about Controversial Issues: Presenting Different Views on Highly Charged Issues.

ERIC Educational Resources Information Center

Goodwin, Jeff

1993-01-01

County agricultural agents (n=258) viewed the "What's the Beef/Here's the Beef" videos, which present contrasting viewpoints on animal rights. Results suggest that well-educated people who have emotional underpinnings on a controversial issue can have their attitudes moderated by exposure to an educational program. (JOW)

Geo-Based Inter-Domain Routing (GIDR) Protocol for MANETS

DTIC Science & Technology

2009-10-01

routing, and support for node mobility. Crowcroft et al. proposed Plutarch as architecture to translate address spaces and transport protocols among...Warfield, “ Plutarch : an argument for network pluralism,” ACM Computer Communication Review, vol. 33, no. 4, pp. 258–266, 2003. [6] S. Schmid, L

77 FR 65875 - Adequacy of Arizona Municipal Solid Waste Landfill Permit Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-31

... Municipal Solid Waste Landfill Permit Program AGENCY: Environmental Protection Agency (EPA). ACTION: Notice... modification to Arizona's municipal solid waste landfill (MSWLF) permit program to allow the State to issue... amending the municipal solid waste landfill criteria at 40 CFR 258.4 to allow for Research, Development...

8 CFR 258.2 - Exceptions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... longshore work at any United States port under the exceptions provided for in paragraphs (a)(2), (b), or (c... hazardous dry bulk cargo. (i) All tankers qualify for the hazardous cargo exception, including parcel tankers, except for a tanker that has been gas-freed to transport non-hazardous dry bulk commodities. (ii...

VizieR Online Data Catalog: LVL global optical photometry (Cook+, 2014)

NASA Astrophysics Data System (ADS)

Cook, D. O.; Dale, D. A.; Johnson, B. D.; van Zee, L.; Lee, J. C.; Kennicutt, R. C.; Calzetti, D.; Staudaher, S. M.; Engelbracht, C. W.

2015-05-01

The LVL sample consists of 258 of our nearest galaxy neighbours reflecting a statistically complete, representative sample of the local Universe. The sample selection and description are detailed in Dale et al. (2009ApJ...703..517D, Cat. J/ApJ/703/517). (4 data files).

VizieR Online Data Catalog: LVL SEDs and physical properties (Cook+, 2014)

NASA Astrophysics Data System (ADS)

Cook, D. O.; Dale, D. A.; Johnson, B. D.; van Zee, L.; Lee, J. C.; Kennicutt, R. C.; Calzetti, D.; Staudaher, S. M.; Engelbracht, C. W.

2015-05-01

The LVL sample consists of 258 of our nearest galaxy neighbours reflecting a statistically complete, representative sample of the local Universe. The sample selection and description are detailed in Dale et al. (2009ApJ...703..517D, Cat. J/ApJ/703/517). (1 data file).

14 CFR 258.5 - Notice requirement.

Code of Federal Regulations, 2010 CFR

2010-01-01

... carrier or ticket agent doing business in the United States shall tell the consumer before booking... itinerary that includes such a service, the selling carrier or ticket agent shall provide the following... for that flight. Further, in the case of some travel, one of your flights may not be identified at the...

42 CFR 403.258 - Statement of actuarial opinion.

Code of Federal Regulations, 2011 CFR

2011-10-01

... actuarial opinion means a signed declaration in which a qualified actuary states that the assumptions used... policy experience, if any, and reasonable expectations. (b) Qualified actuary means— (1) A member in good standing of the American Academy of Actuaries; or (2) A person who has otherwise demonstrated his or her...

42 CFR 403.258 - Statement of actuarial opinion.

Code of Federal Regulations, 2012 CFR

2012-10-01

... actuarial opinion means a signed declaration in which a qualified actuary states that the assumptions used... policy experience, if any, and reasonable expectations. (b) Qualified actuary means— (1) A member in good standing of the American Academy of Actuaries; or (2) A person who has otherwise demonstrated his or her...

42 CFR 403.258 - Statement of actuarial opinion.

Code of Federal Regulations, 2013 CFR

2013-10-01

... actuarial opinion means a signed declaration in which a qualified actuary states that the assumptions used... policy experience, if any, and reasonable expectations. (b) Qualified actuary means— (1) A member in good standing of the American Academy of Actuaries; or (2) A person who has otherwise demonstrated his or her...

42 CFR 403.258 - Statement of actuarial opinion.

Code of Federal Regulations, 2014 CFR

2014-10-01

... actuarial opinion means a signed declaration in which a qualified actuary states that the assumptions used... policy experience, if any, and reasonable expectations. (b) Qualified actuary means— (1) A member in good standing of the American Academy of Actuaries; or (2) A person who has otherwise demonstrated his or her...

19 CFR 146.6 - Procedure for activation.

Code of Federal Regulations, 2011 CFR

2011-04-01

... operator or grantee to submit fingerprints on form FD 258 or electronically at the time of filing the application. If the operator is an individual, that individual's fingerprints may be required. If the operator or grantee is a business entity, fingerprints of all officers and managing officials may be required...

19 CFR 122.182 - Security provisions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... port director may require the applicant to submit fingerprints on form FD-258 or on any other approved... fingerprint checks and the Customs administrative processing fee, the total of which must be tendered by, or... require the submission of fingerprints as provided in paragraph (c)(1)(i) of this section. The new...