A Management Analysis and Systems Model of Department of Defense Acquisition Structure and Policy

DTIC Science & Technology

1988-01-01

Production Cost 253 0 104. Structure for Capacity Utilized Effect on Production Cost 254 105. Actual vs Model GNP (1960-1985) 265 106. Actual vs Model Social...Spending (1960-1985) 266 107. Actual vs Model Defense Spending (1960-1985) 267 108. Actual vs Model Soviet Defense Expenditures 268 109. Comparison of...Actual GNP a. 800 z 0 600 400 " I I 50 60 70 80 90 Year Figure 105. Actual vs Model GNP (1960-1985) fact that the model did not generate real

Readiness for Implementation of Lung Cancer Screening. A National Survey of Veterans Affairs Pulmonologists.

PubMed

Tukey, Melissa H; Clark, Jack A; Bolton, Rendelle; Kelley, Michael J; Slatore, Christopher G; Au, David H; Wiener, Renda Soylemez

2016-10-01

To mitigate the potential harms of screening, professional societies recommend that lung cancer screening be conducted in multidisciplinary programs with the capacity to provide comprehensive care, from screening through pulmonary nodule evaluation to treatment of screen-detected cancers. The degree to which this standard can be met at the national level is unknown. To assess the readiness of clinical facilities in a national healthcare system for implementation of comprehensive lung cancer screening programs, as compared with the ideal described in policy recommendations. This was a cross-sectional, self-administered survey of staff pulmonologists in pulmonary outpatient clinics in Veterans Health Administration facilities. The facility-level response rate was 84.1% (106 of 126 facilities with pulmonary clinics); 88.7% of facilities showed favorable provider perceptions of the evidence for lung cancer screening, and 73.6% of facilities had a favorable provider-perceived local context for screening implementation. All elements of the policy-recommended infrastructure for comprehensive screening programs were present in 36 of 106 facilities (34.0%); the most common deficiencies were the lack of on-site positron emission tomography scanners or radiation oncology services. Overall, 26.5% of Veterans Health Administration facilities were ideally prepared for lung cancer screening implementation (44.1% if the policy recommendations for on-site positron emission tomography scanners and radiation oncology services were waived). Many facilities may be less than ideally positioned for the implementation of comprehensive lung cancer screening programs. To ensure safe, effective screening, hospitals may need to invest resources or coordinate care with facilities that can offer comprehensive care for screening through downstream evaluation and treatment of screen-detected cancers.

TERT promoter mutations in thyroid cancer: a report from a Middle Eastern population.

PubMed

Qasem, Ebtesam; Murugan, Avaniyapuram Kannan; Al-Hindi, Hindi; Xing, Mingzhao; Almohanna, Mai; Alswailem, Meshael; Alzahrani, Ali S

2015-12-01

Telomerase reverse transcriptase (TERT) promoter mutations C228T and C250T have recently been described in follicular cell-derived thyroid cancer (TC) in patients from North America and Europe. In this study, we explored whether these findings could be replicated in patients from a different ethnic group. We screened 17 benign thyroid adenomas and 265 TC samples from patients in the Middle East for these mutations by PCR and direct sequencing using DNA isolated from paraffin-embedded tumor tissues. None of the 17 benign adenomas harbored TERT promoter mutations. Of 265 TC, 34 (12.8%) harbored TERT promoter mutations, including 10/153 (6.5%) conventional papillary TC (CPTC), 8/57 (14.0%) follicular variant PTC, 9/30 (30%) tall cell variant PTC, 1/3 (30%) Hurthle cell thyroid cancer (HTC), 1/5 (20%) follicular TC, and 5/13 (38.5%) poorly differentiated TC. C250T mutation was present in only 6/265 (2.3%) cases, while C228T mutation was present in a total of 28/265 (10.6%) cases. These two mutations were mutually exclusive. TERT promoter mutations were significantly more common in older (≥45 years) than younger patients and were associated with larger tumour size, vascular invasion, higher TNM stage (stage III and IV), BRAF(V600E) mutation and persistent/recurrent disease at 6-12 months after initial treatment and at the last follow up. These associations were stronger in non-CPTC. Thus, this study on a large cohort of TC patients from Middle East demonstrates that TERT promoter mutations are relatively common, especially in the non-CPTC, and are associated with more aggressive histopathological features, BRAF(V600E) mutation, and disease persistence/recurrence than the WT TERT. © 2015 Society for Endocrinology.

Cloning and characterization of the ONAC106 gene from Oryza sativa cultivar Kuku Belang

NASA Astrophysics Data System (ADS)

Basri, Khairunnisa; Sukiran, Noor Liyana; Zainal, Zamri

2016-11-01

Plants possess different mechanisms in stress response, where induction of stress-responsive genes provides tolerance to unfavorable conditions. Stress-responsive genes are characterized for functional and regulatory genes that help in overcoming stress by molecular, biochemical and morphological adaptations. NAC transcription factors are one of the regulatory proteins that involved in stress signaling pathway. A putative NAC transcription factor, ONAC016 was identified from drought transcriptomic data. Our data suggested that ONAC106 was induced by drought, but its function in abiotic stress is still unclear. In silico analysis of ONAC106 showed that this gene encodes 334 amino acids, and its protein consists of NAM (No Apical Meristem) domain. The orthologue of ONAC106 was present in several Poaceae family members, suggesting that ONAC106 is unique to monocot plants only. We found that ONAC106 was induced by salt and cold stresses, indicating that this gene involves in abiotic stress response. In addition, we also found that ONAC106 might function in defense response to pathogen invasion. The ABRE (Abscisic Acid Regulatory Element) cis-element was identified in the promoter region of ONAC106, suggesting that it may involve in the abscisic acid (ABA)-dependent signaling pathway. Based on this preliminary result, we hypothesize that ONAC106 may play a role in abiotic stress response by regulating ABA-responsive genes.

The Region between Amino Acids 245 and 265 of the Bovine Leukemia Virus (BLV) Tax Protein Restricts Transactivation Not Only via the BLV Enhancer but Also via Other Retrovirus Enhancers

PubMed Central

Tajima, Shigeru; Aida, Yoko

2000-01-01

Bovine leukemia virus (BLV) is associated with enzootic bovine leukosis and is closely related to human T-cell leukemia virus type 1 (HTLV-1). The Tax protein of BLV acts through the 5′ long terminal repeat (LTR) of BLV and activates the transcription of BLV. In this study, we amplified tax genes from BLV-infected cattle using PCR. We cloned the genes and monitored the transcriptional activities of the products. Seven independent mutant Tax proteins, with at least one amino acid substitution between residues 240 and 265, exhibited a markedly stronger ability to stimulate the viral LTR-directed transcription than the wild-type Tax protein. Analysis of chimeric Tax proteins derived from wild-type and mutant Tax proteins clearly demonstrated that a single substitution between residue 240 and 265 might be critical for the higher activities of the Tax mutant proteins. Furthermore, it appeared that transient expression of a Tax mutant protein was better able to increase the production of viral proteins and particles from a defective recombinant proviral clone of BLV than was wild-type Tax. Analysis of mutations within the U3 region of the LTR revealed that a cyclic AMP-responsive element in Tax-responsive element 2 might be sufficient for the enhanced activation mediated by the mutant proteins. In addition to the LTR of BLV, other viral enhancers, such as the enhancers of HTLV-1 and of mouse mammary tumor virus, which cannot be activated by wild-type BLV Tax protein, were activated by a Tax mutant protein. Our observations suggest that the transactivation activity and target sequence specificity of BLV Tax might be limited or negatively regulated by the region of the protein between amino acids 240 and 265. PMID:11069988

An environmental assessment of United States drinking water watersheds

Treesearch

James Wickham; Timothy Wade; Kurt Riitters

2011-01-01

Abstract There is an emerging recognition that natural lands and their conservation are important elements of a sustainable drinking water infrastructure. We conducted a national, watershed-level environmental assessment of 5,265 drinking water watersheds using data on land cover, hydrography and conservation status. Approximately 78% of the conterminous United States...

The accuracy of estimates of the overturning circulation from basin-wide mooring arrays

NASA Astrophysics Data System (ADS)

Sinha, B.; Smeed, D. A.; McCarthy, G.; Moat, B. I.; Josey, S. A.; Hirschi, J. J.-M.; Frajka-Williams, E.; Blaker, A. T.; Rayner, D.; Madec, G.

2018-01-01

Previous modeling and observational studies have established that it is possible to accurately monitor the Atlantic Meridional Overturning Circulation (AMOC) at 26.5°N using a coast-to-coast array of instrumented moorings supplemented by direct transport measurements in key boundary regions (the RAPID/MOCHA/WBTS Array). The main sources of observational and structural errors have been identified in a variety of individual studies. Here a unified framework for identifying and quantifying structural errors associated with the RAPID array-based AMOC estimates is established using a high-resolution (eddy resolving at low-mid latitudes, eddy permitting elsewhere) ocean general circulation model, which simulates the ocean state between 1978 and 2010. We define a virtual RAPID array in the model in close analogy to the real RAPID array and compare the AMOC estimate from the virtual array with the true model AMOC. The model analysis suggests that the RAPID method underestimates the mean AMOC by ∼1.5 Sv (1 Sv = 106 m3 s-1) at ∼900 m depth, however it captures the variability to high accuracy. We examine three major contributions to the streamfunction bias: (i) due to the assumption of a single fixed reference level for calculation of geostrophic transports, (ii) due to regions not sampled by the array and (iii) due to ageostrophic transport. A key element in (i) and (iii) is use of the model sea surface height to establish the true (or absolute) geostrophic transport. In the upper 2000 m, we find that the reference level bias is strongest and most variable in time, whereas the bias due to unsampled regions is largest below 3000 m. The ageostrophic transport is significant in the upper 1000 m but shows very little variability. The results establish, for the first time, the uncertainty of the AMOC estimate due to the combined structural errors in the measurement design and suggest ways in which the error could be reduced. Our work has applications to basin-wide circulation measurement arrays at other latitudes and in other basins as well as quantifying systematic errors in ocean model estimates of the AMOC at 26.5°N.

Compositionally graded relaxed AlGaN buffers on semipolar GaN for mid-ultraviolet emission

NASA Astrophysics Data System (ADS)

Young, Erin C.; Wu, Feng; Romanov, Alexey E.; Haeger, Daniel A.; Nakamura, Shuji; Denbaars, Steven P.; Cohen, Daniel A.; Speck, James S.

2012-10-01

In this Letter, we report on the growth and properties of relaxed, compositionally graded AlxGa1 - xN buffer layers on freestanding semipolar (202¯1) GaN substrates. Continuous and step compositional grades with Al concentrations up to x = 0.61 have been achieved, with emission wavelengths in the mid-ultraviolet region as low as 265 nm. Coherency stresses were relaxed progressively throughout the grades by misfit dislocation generation via primary (basal) slip and secondary (non-basal) slip systems. Threading dislocation densities in the final layers of the grades were less than 106/cm2 as confirmed by plan-view transmission electron microscopy and cathodoluminescence studies.

Nonlinear Finite Element Analysis of Metals and Metal Matrix Composites: A Local-Global Investigation

DTIC Science & Technology

1992-10-01

and SiC/Al [47] possess good chemical bonding and experience mechanical clamping due to the differences in thermal expansion coefficients between...Coefficient of Thermal 2.70 x 10.6 *F-1 4.09 x 10-6 *C-1 Expansion (ca) Poisson’s Ratio (v) 0.25 0.25 Fiber Diameter (d) 0.0056 in 0.014224 cm...Properties of the matrix (as fabricated) Coefficient of Thermal 5.4 x 10-6 "F1 9.72 x 10-6 "C-1 Expansion (a) Poisson’s Ratio (v) 0.351 0.351 Longitudinal

Ga2O3 Schottky rectifiers with 1 ampere forward current, 650 V reverse breakdown and 26.5 MW.cm-2 figure-of-merit

NASA Astrophysics Data System (ADS)

Yang, Jiancheng; Ren, F.; Tadjer, Marko; Pearton, S. J.; Kuramata, A.

2018-05-01

A key goal for Ga2O3 rectifiers is to achieve high forward currents and high reverse breakdown voltages. Field-plated β-Ga2O3 Schottky rectifiers with area 0.01 cm2, fabricated on 10 μm thick, lightly-doped drift regions (1.33 x 1016 cm-3) on heavily-doped (3.6 x 1018 cm-3) substrates, exhibited forward current density of 100A.cm-2 at 2.1 V, with absolute current of 1 A at this voltage and a reverse breakdown voltage (VB) of 650V. The on-resistance (RON) was 1.58 x 10-2 Ω.cm2, producing a figure of merit (VB2/RON) of 26.5 MW.cm-2. The Schottky barrier height of the Ni was 1.04 eV, with an ideality factor of 1.02. The on/off ratio was in the range 3.3 x 106 - 5.7 x 109 for reverse biases between 5 and 100V. The reverse recovery time was ˜30 ns for switching from +2V to -5V. The results show the capability of β-Ga2O3 rectifiers to achieve exceptional performance in both forward and reverse bias conditions.

Tracing metal-silicate segregation and late veneer in the Earth and the ureilite parent body with palladium stable isotopes

NASA Astrophysics Data System (ADS)

Creech, J. B.; Moynier, F.; Bizzarro, M.

2017-11-01

Stable isotope studies of highly siderophile elements (HSE) have the potential to yield valuable insights into a range of geological processes. In particular, the strong partitioning of these elements into metal over silicates may lead to stable isotope fractionation during metal-silicate segregation, making them sensitive tracers of planetary differentiation processes. We present the first techniques for the precise determination of palladium stable isotopes by MC-ICPMS using a 106Pd-110Pd double-spike to correct for instrumental mass fractionation. Results are expressed as the per mil (‰) difference in the 106Pd/105Pd ratio (δ106Pd) relative to an in-house solution standard (Pd_IPGP) in the absence of a certified Pd isotopic standard. Repeated analyses of the Pd isotopic composition of the chondrite Allende demonstrate the external reproducibility of the technique of ±0.032‰ on δ106Pd. Using these techniques, we have analysed Pd stable isotopes from a range of terrestrial and extraterrestrial samples. We find that chondrites define a mean δ106Pdchondrite = -0.19 ± 0.05‰. Ureilites reveal a weak trend towards heavier δ106Pd with decreasing Pd content, similar to recent findings based on Pt stable isotopes (Creech et al., 2017), although fractionation of Pd isotopes is significantly less than for Pt, possibly related to its weaker metal-silicate partitioning behaviour and the limited field shift effect. Terrestrial mantle samples have a mean δ106Pdmantle = -0.182 ± 0.130‰, which is consistent with a late-veneer of chondritic material after core formation.

High-Resolution CCD Spectra of Stars in Globular Clusters. IX. The "Young" Clusters Ruprecht 106 and PAL 12

NASA Astrophysics Data System (ADS)

Brown, Jeffrey A.; Wallerstein, George; Zucker, Daniel

1997-07-01

We have performed a spectroscopic abundance analysis of two stars each in the anomalously young globular clusters Rup 106 and Pal 12. We find [Fe/H] =~ -1.45 for Rup 106 and -1.0 for Pal 12. The abundance ratios in both clusters are peculiar in comparison to other globulars: the alpha -elements are not enhanced over the solar ratio. We find that oxygen in Rup 106 is also relatively low, with [O/Fe] =~ 0.0 - +0.1. The similarity of the ratio of the alpha-elements to iron to the solar ratio shows that species contributed by supernovae of type Ia have ``caught up" with species produced by SN II's. The similar contributions of the alpha - and Fe-peak species to disk stars shows that age, not metallicity, is the determining factor in the ratio of SN II/SN Ia nucleosynthesis. Galactic enrichment models show that these abundance ratios can be understood as being the result of these two clusters coming from an environment with multiple discontinuous star formation events.

45 CFR 265.3 - What reports must the State file on a quarterly basis?

Code of Federal Regulations, 2010 CFR

2010-10-01

...) must collect on a monthly basis, and file on a quarterly basis, the data specified in the SSP-MOE Data... provided at § 264.85 of this chapter, in lieu of the TANF Financial Report. (d) SSP-MOE Data Report. The SSP-MOE Data Report consists of four sections. Two sections contain disaggregated data elements and...

40 CFR 265.15 - General inspection requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

....g., inoperative sump pump, leaking fitting, eroding dike, etc.). (4) The frequency of inspection may vary for the items on the schedule. However, the frequency should be based on the rate of deterioration... and frequencies called for in §§ 265.174, 265.193, 265.195, 265.226, 265.260, 265.278, 265.304, 265...

Magma Chamber of the 26.5 ka Oruanui Eruption, Taupo Volcano, New Zealand

NASA Astrophysics Data System (ADS)

Liu, Y.; Anderson, A. T.; Wilson, C. J.; Davis, A. M.

2004-12-01

We have investigated melt inclusions and their host quartz crystals from the Bishop-Tuff-sized 26.5 ka Oruanui eruption at Taupo volcano, New Zealand. Compositions (major and trace elements, H2O and CO2) of melt inclusions and cathodoluminescence (CL) images of quartz were obtained for eight individual pumices from early, middle and late depositional units. All melt inclusions are high-silica weakly peraluminous rhyolites. Melt inclusions for different eruptive phases have similar ranges of H2O contents (3.8-5.2 wt %), but late-erupted samples have higher CO2 contents (mostly > 140 ppm). A positive correlation between CO2 and compatible trace elements such as Sr suggests that crystallization and melt entrapment occurred under gas-saturated conditions. Trace elements variations in melt inclusions are consistent with fractionation of 30-40 wt % crystals (plagioclase+quartz+pyroxene+amphibole). Crystal contents in pumices, trace-element contents in melt inclusions, and CL zoning patterns of quartz show no correlation with eruptive phases, suggesting that the Oruanui magma was well mixed before eruption. Some Oruanui quartz crystals contain distinctive CL zonings with a jagged ('restitic') core mantled by a black CL zone. Trace element variations in melt inclusions in the 'restitic' cores are consistent with fractionation of Ba-bearing minerals such as sanidine and/or biotite, both of which are rare or absent in rocks erupted from Taupo volcanic center. The above evidence suggests that Oruanui rhyolite is generated by assimilation of previous intruded rocks or country rocks, differentiated by crystal fractionation, and then mixed prior to eruption. Despite the differences in trace element and volatile contents, and crystal assemblages, both Bishop Tuff and Oruanui magmas involve crystal fractionation as one of the main differentiation mechanisms during their evolution. However, there are pronounced differences in the pre-eruptive stratification of the two chambers, which may reflect the tectonic settings, eruption rates, and ages of the systems.

Performance analysis of boron nitride embedded armchair graphene nanoribbon metal-oxide-semiconductor field effect transistor with Stone Wales defects

NASA Astrophysics Data System (ADS)

Chanana, Anuja; Sengupta, Amretashis; Mahapatra, Santanu

2014-01-01

We study the performance of a hybrid Graphene-Boron Nitride armchair nanoribbon (a-GNR-BN) n-MOSFET at its ballistic transport limit. We consider three geometric configurations 3p, 3p + 1, and 3p + 2 of a-GNR-BN with BN atoms embedded on either side (2, 4, and 6 BN) on the GNR. Material properties like band gap, effective mass, and density of states of these H-passivated structures are evaluated using the Density Functional Theory. Using these material parameters, self-consistent Poisson-Schrodinger simulations are carried out under the Non Equilibrium Green's Function formalism to calculate the ballistic n-MOSFET device characteristics. For a hybrid nanoribbon of width ˜5 nm, the simulated ON current is found to be in the range of 265 μA-280 μA with an ON/OFF ratio 7.1 × 106-7.4 × 106 for a VDD = 0.68 V corresponding to 10 nm technology node. We further study the impact of randomly distributed Stone Wales (SW) defects in these hybrid structures and only 2.5% degradation of ON current is observed for SW defect density of 3.18%.

45 CFR 265.8 - Under what circumstances will we take action to impose a reporting penalty for failure to submit...

Code of Federal Regulations, 2010 CFR

2010-10-01

... TANF Financial Report (or, as applicable, the Territorial Financial Report), or the quarterly SSP-MOE... TANF Data Report or the SSP-MOE Data Report are not accurate or a report does not include all the data... security number; (3) The aggregated data elements in the TANF Data Report or the SSP-MOE Data Report...

Echelle Spectroscopy and Abundances in Ruprecht 106 and ARP 2

NASA Astrophysics Data System (ADS)

Brown, Jeffery A.; Wallerstein, George; Zucker, Daniel

1996-04-01

This is a preliminary report on abundances for two red giants each in the young globular clusters Ruprecht 106 and Pal 12. For Rup 106, we find [Fe/H] = -1.50 but almost all other elements are more deficient than iron, in reverse of the pattern in most metal-poor stars; the exception is oxygen, with [O/Fe] =~ 0.0. Pal 12 is less depleted, with [Fe/H] = -1.0, and has more nearly solar abundance ratios; we have no data on oxygen in Pal 12.

New approach to the fast screening of plant oil samples for F-, Cl-, Br- and S-organic compounds on the trace level.

PubMed

Chivarzin, M E; Revelsky, I A; Nikoshina, A V; Buldyzkova, A N; Chepeliansky, D A; Revelsky, A I; Buriak, A K

2016-04-01

The fast method of the simultaneous determination of F(-), Cl(-), Br(-) and SO4(2-) anions in the deionized water on the trace level by ion chromatography using thorough cleaning of respective water containers, 10 μM NaHCO3 water solution as eluent, short Metrohm (50 × 4 mm) separation column and a large water volume injection is proposed. Calculated detection limits are 10(-9)-10(-8)% depending on the element. The method for the fast screening of plant oil samples for the total fluorine-, chlorine-, bromine- and sulfur-organic compounds content (calculated for the respective elements) on the trace level is developed. It is based on the high temperature combustion of oil sample in oxygen flow, absorption of the conversion products in deionized water and whole absorbate volume analysis for F(-), Cl(-), Br(-) and SO4(2-) anions, corresponding to the respective elements, using the developed method of these anions analysis by ion chromatography. The samples of soya, olive, sunflower and cotton seed oil were analyzed. The method detection limits (for 1mg sample) were 2 × 10(-6)%, 2 × 10(-6)%, 5 × 10(-6)% and 5 × 10(-6)% for fluorine, chlorine, bromine and sulfur, respectively. The relative standard deviation was ≤ 15%. The method gives the compressed information about the total content of all target and nontarget fluorine-, chlorine-, bromine- and sulfur-organic compounds in plant oils. Copyright © 2015. Published by Elsevier B.V.

Comparison of Impurities in Charcoal Sorbents Found by Neutron Activation Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doll, Charles G.; Finn, Erin C.; Cantaloub, Michael G.

2013-01-01

Abstract: Neutron activation of gas samples in a reactor often requires a medium to retain sufficient amounts of the gas for analysis. Charcoal is commonly used to adsorb gas and hold it for activation; however, the amount of activated sodium in the charcoal after irradiation swamps most signals of interest. Neutron activation analysis (NAA) was performed on several commonly available charcoal samples in an effort to determine the activation background. The results for several elements, including the dominant sodium element, are reported. It was found that ECN charcoal had the lowest elemental background, containing sodium at 2.65 ± 0.05 ppm,more » as well as trace levels of copper and tungsten.« less

Exaptation of Bornavirus-Like Nucleoprotein Elements in Afrotherians

PubMed Central

Kobayashi, Yuki; Horie, Masayuki; Nakano, Ayumi; Murata, Koichi; Itou, Takuya; Suzuki, Yoshiyuki

2016-01-01

Endogenous bornavirus-like nucleoprotein elements (EBLNs), the nucleotide sequence elements derived from the nucleoprotein gene of ancient bornavirus-like viruses, have been identified in many animal genomes. Here we show evidence that EBLNs encode functional proteins in their host. Some afrotherian EBLNs were observed to have been maintained for more than 83.3 million years under negative selection. Splice variants were expressed from the genomic loci of EBLNs in elephant, and some were translated into proteins. The EBLN proteins appeared to be localized to the rough endoplasmic reticulum in African elephant cells, in contrast to the nuclear localization of bornavirus N. These observations suggest that afrotherian EBLNs have acquired a novel function in their host. Interestingly, genomic sequences of the first exon and its flanking regions in these EBLN loci were homologous to those of transmembrane protein 106B (TMEM106B). The upstream region of the first exon in the EBLN loci exhibited a promoter activity, suggesting that the ability of these EBLNs to be transcribed in the host cell was gained through capturing a partial duplicate of TMEM106B. In conclusion, our results strongly support for exaptation of EBLNs to encode host proteins in afrotherians. PMID:27518265

106-17 Telemetry Standards Chapter 1

DTIC Science & Technology

2017-07-01

Telemetry Standards , RCC Standard 106-17 Chapter 1, July 2017 1-1 CHAPTER 1 Introduction The Telemetry Standards address the here-to-date...generally devoted to a different element of the telemetry system or process . Chapters 21 through 28 address the topic of network telemetry. These...Commonly used terms are defined in standard reference glossaries and dictionaries. Definitions of terms with special applications are included when

40 CFR 265.273 - Waste analysis.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Waste analysis. 265.273 Section 265... FACILITIES Land Treatment § 265.273 Waste analysis. In addition to the waste analyses required by § 265.13... listed as a hazardous waste. As required by § 265.13, the waste analysis plan must include analyses...

The environmental and economic impact of removing growth-enhancing technologies from U.S. beef production.

PubMed

Capper, J L; Hayes, D J

2012-10-01

The objective of this study was to quantify the environmental and economic impact of withdrawing growth-enhancing technologies (GET) from the U.S. beef production system. A deterministic model based on the metabolism and nutrient requirements of the beef population was used to quantify resource inputs and waste outputs per 454 × 10(6) kg of beef. Two production systems were compared: one using GET (steroid implants, in-feed ionophores, in-feed hormones, and beta-adrenergic agonists) where approved by FDA at current adoption rates and the other without GET use. Both systems were modeled using characteristic management practices, population dynamics, and production data from U.S. beef systems. The economic impact and global trade and carbon implications of GET withdrawal were calculated based on feed savings. Withdrawing GET from U.S. beef production reduced productivity (growth rate and slaughter weight) and increased the population size required to produce 454 × 10(6) kg beef by 385 × 10(3) animals. Feedstuff and land use were increased by 2,830 × 10(3) t and 265 × 10(3) ha, respectively, by GET withdrawal, with 20,139 × 10(6) more liters of water being required to maintain beef production. Manure output increased by 1,799 × 10(3) t as a result of GET withdrawal, with an increase in carbon emissions of 714,515 t/454 × 10(6) kg beef. The projected increased costs of U.S. beef produced without GET resulted in the effective implementation of an 8.2% tax on beef production, leading to reduced global trade and competitiveness. To compensate for the increase in U.S. beef prices and maintain beef supply, it would be necessary to increase beef production in other global regions, with a projected increase in carbon emissions from deforestation, particularly in Brazil. Withdrawing GET from U.S. beef production would reduce both the economic and environmental sustainability of the industry.

Passive mode lockers for lasers generating at a wavelength of 1.06 micron

NASA Astrophysics Data System (ADS)

Mikhailov, V. P.; Demchuk, M. I.; Lugovskii, A. P.; Sosnovskii, G. M.; Iumashev, K. V.

1983-04-01

New polymethine dyes that can be used for the passive mode locking of lasers generating at 1.06 micron are investigated using YAG:Nd as the active element. The effect of introducing various substituents into the heterocyclic nuclei of the end groups of polymethine dyes is discussed. It is shown that substituents generally increase the energy of the ultrashort pulse while also increasing its length.

DNS of Low-Pressure Turbine Cascade Flows with Elevated Inflow Turbulence Using a Discontinuous-Galerkin Spectral-Element Method

NASA Technical Reports Server (NTRS)

Garai, Anirban; Diosady, Laslo T.; Murman, Scott M.; Madavan, Nateri K.

2016-01-01

Recent progress towards developing a new computational capability for accurate and efficient high-fidelity direct numerical simulation (DNS) and large-eddy simulation (LES) of turbomachinery is described. This capability is based on an entropy- stable Discontinuous-Galerkin spectral-element approach that extends to arbitrarily high orders of spatial and temporal accuracy, and is implemented in a computationally efficient manner on a modern high performance computer architecture. An inflow turbulence generation procedure based on a linear forcing approach has been incorporated in this framework and DNS conducted to study the effect of inflow turbulence on the suction- side separation bubble in low-pressure turbine (LPT) cascades. The T106 series of airfoil cascades in both lightly (T106A) and highly loaded (T106C) configurations at exit isentropic Reynolds numbers of 60,000 and 80,000, respectively, are considered. The numerical simulations are performed using 8th-order accurate spatial and 4th-order accurate temporal discretization. The changes in separation bubble topology due to elevated inflow turbulence is captured by the present method and the physical mechanisms leading to the changes are explained. The present results are in good agreement with prior numerical simulations but some expected discrepancies with the experimental data for the T106C case are noted and discussed.

Energy Transfer between Post-Transition Elements & Rare Earths in Oxide & Chalcogenide Glasses.

DTIC Science & Technology

1979-08-27

Caird [13]. A calculation of reduced matrix elements of Pr3 in 20 Na O • 80 TeO2 glass [14] showed that they differ slightly from data of ref. [121... glasses Transition (lass 35 ZnO 65 TeO2 20 Na2 O 80 TeO 2 fX 106 fX 106 l.,eas 3a, a) Ia’l. faI f.me.s f al f+ I fal 3 H4 - 3 H6 1.56 1.65 1.12...Rare-Earth Doped Glasses 20. jIST HAEV CCnFn~m ,i cn,on ra e sideit If c."*Ar’ -- ~ 14-r by t?-h.c .: r Intensity parameters, radiative transition

Theoretical predictions of properties and gas-phase chromatography behaviour of carbonyl complexes of group-6 elements Cr, Mo, W, and element 106, Sg.

PubMed

Pershina, V; Anton, J

2013-05-07

Fully relativistic, four-component density functional theory electronic structure calculations were performed for M(CO)6 of group-6 elements Cr, Mo, W, and element 106, Sg, with an aim to predict their adsorption behaviour in the gas-phase chromatography experiments. It was shown that seaborgium hexacarbonyl has a longer M-CO bond, smaller ionization potential, and larger polarizability than the other group-6 molecules. This is explained by the increasing relativistic expansion and destabilization of the (n - 1)d AOs with increasing Z in the group. Using results of the calculations, adsorption enthalpies of the group-6 hexacarbonyls on a quartz surface were predicted via a model of physisorption. According to the results, -ΔHads should decrease from Mo to W, while it should be almost equal--within the experimental error bars--for W and Sg. Thus, we expect that in the future gas-phase chromatography experiments it will be almost impossible--what concerns ΔHads--to distinguish between the W and Sg hexacarbonyls by their deposition on quartz.

Nature Elements and Fundamental Motor Skill Development Opportunities at Five Elementary School Districts in British Columbia

PubMed Central

Lim, Christopher; Donovan, Andrew M.; Naylor, Patti-Jean

2017-01-01

The majority of Canadian children are not physically active enough for healthy development. School playgrounds are a primary location to promote physical activity and motor skill practice. The benefits of children’s play in nature have also been highlighted, but few studies have evaluated children’s access and exposure to nature for play on school grounds. This study examined children’s access to nature on school grounds and the opportunities afforded by those natural elements for motor skill practice. Results: Extensive naturescapes (multiple nature elements in one setting) were not common, and natural elements were limited, ranging from 1.97 to 5.71 elements/school. The most common element was a forested area (26.5% of all natural elements identified). In comparison to built structures, the number of natural elements was low. Some elements differed between school districts and appeared to be related to local geography and terrain (hilly, rocky terrain, tidal flats, etc.). Our assessment showed that naturescape elements afforded opportunities for the development of some key fundamental motor skills (FMS), specifically, locomotor and stability skills, but opportunities to develop manipulative skills were limited. To maximize potential FMS development, physical literacy, and psycho-social benefits, additional elements or more comprehensive multi-element naturescapes and facilitation (social or environmental) are recommended. PMID:29064430

Nature Elements and Fundamental Motor Skill Development Opportunities at Five Elementary School Districts in British Columbia.

PubMed

Lim, Christopher; Donovan, Andrew M; Harper, Nevin J; Naylor, Patti-Jean

2017-10-24

The majority of Canadian children are not physically active enough for healthy development. School playgrounds are a primary location to promote physical activity and motor skill practice. The benefits of children's play in nature have also been highlighted, but few studies have evaluated children's access and exposure to nature for play on school grounds. This study examined children's access to nature on school grounds and the opportunities afforded by those natural elements for motor skill practice. Extensive naturescapes (multiple nature elements in one setting) were not common, and natural elements were limited, ranging from 1.97 to 5.71 elements/school. The most common element was a forested area (26.5% of all natural elements identified). In comparison to built structures, the number of natural elements was low. Some elements differed between school districts and appeared to be related to local geography and terrain (hilly, rocky terrain, tidal flats, etc.). Our assessment showed that naturescape elements afforded opportunities for the development of some key fundamental motor skills (FMS), specifically, locomotor and stability skills, but opportunities to develop manipulative skills were limited. To maximize potential FMS development, physical literacy, and psycho-social benefits, additional elements or more comprehensive multi-element naturescapes and facilitation (social or environmental) are recommended.

40 CFR 265.341 - Waste analysis.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Waste analysis. 265.341 Section 265... FACILITIES Incinerators § 265.341 Waste analysis. In addition to the waste analyses required by § 265.13, the... minimum, the analysis must determine: (a) Heating value of the waste; (b) Halogen content and sulfur...

40 CFR 265.375 - Waste analysis.

Code of Federal Regulations, 2012 CFR

2012-07-01

... each waste analysis, or the documented information, in the operating record of the facility.] ... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Waste analysis. 265.375 Section 265... FACILITIES Thermal Treatment § 265.375 Waste analysis. In addition to the waste analyses required by § 265.13...

40 CFR 265.375 - Waste analysis.

Code of Federal Regulations, 2010 CFR

2010-07-01

... each waste analysis, or the documented information, in the operating record of the facility.] ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Waste analysis. 265.375 Section 265... FACILITIES Thermal Treatment § 265.375 Waste analysis. In addition to the waste analyses required by § 265.13...

40 CFR 265.341 - Waste analysis.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Waste analysis. 265.341 Section 265... FACILITIES Incinerators § 265.341 Waste analysis. In addition to the waste analyses required by § 265.13, the... minimum, the analysis must determine: (a) Heating value of the waste; (b) Halogen content and sulfur...

Hydrogen-rich scandium compounds at high pressures

NASA Astrophysics Data System (ADS)

Abe, Kazutaka

2017-10-01

Scandium hydrides at high pressures have been investigated by using ab initio density functional calculations. Although the stable scandium hydride so far known to have the highest content rate of hydrogen is ScH3, other more hydrogen-rich compounds are found to be possible at high pressures. These are ScH4 in the I 4 /m m m structure above 160 GPa, ScH6 in the P 63/m m c structure from 135 to 265 GPa, and ScH6 in the I m 3 ¯m structure above 265 GPa. The three phases are all metallic, and the superconducting transition temperatures estimated from the extended McMillan equation are 67 K in the I 4 /m m m ScH4 at 195 GPa, 63 K in the P 63/m m c ScH6 at 145 GPa, and 130 K in the I m 3 ¯m ScH6 at 285 GPa. While the I 4 /m m m tetrahydride and the I m 3 ¯m hexahydride were similarly predicted for yttrium (another group-3 element), the P 63/m m c hexahydride is possible only for scandium. The smaller atomic size of scandium stabilizes the P 63/m m c structure, and other nearby d -block elements, whose atomic sizes are smaller or comparable, might be likewise capable of forming such polyhydrides.

40 CFR 265.375 - Waste analysis.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Waste analysis. 265.375 Section 265... FACILITIES Thermal Treatment § 265.375 Waste analysis. In addition to the waste analyses required by § 265.13... of pollutants which might be emitted. At a minimum, the analysis must determine: (a) Heating value of...

40 CFR 265.252 - Waste analysis.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Waste analysis. 265.252 Section 265... FACILITIES Waste Piles § 265.252 Waste analysis. In addition to the waste analyses required by § 265.13, the... in the pile to which it is to be added. The analysis conducted must be capable of differentiating...

40 CFR 265.273 - Waste analysis.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Waste analysis. 265.273 Section 265... FACILITIES Land Treatment § 265.273 Waste analysis. In addition to the waste analyses required by § 265.13... any substances which caused the waste to be listed as a hazardous waste; and (c) If food chain crops...

40 CFR 265.273 - Waste analysis.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Waste analysis. 265.273 Section 265... FACILITIES Land Treatment § 265.273 Waste analysis. In addition to the waste analyses required by § 265.13... any substances which caused the waste to be listed as a hazardous waste; and (c) If food chain crops...

14 CFR 26.5 - Applicability table.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Note: By Doc. No. FAA-2006-24282, Nov. 15, 2010, § 26.5 was revised, effective Jan. 14, 2011. For the... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Applicability table. 26.5 Section 26.5... AIRWORTHINESS AND SAFETY IMPROVEMENTS FOR TRANSPORT CATEGORY AIRPLANES General § 26.5 Applicability table. Link...

40 CFR 265.52 - Content of contingency plan.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Content of contingency plan. 265.52... DISPOSAL FACILITIES Contingency Plan and Emergency Procedures § 265.52 Content of contingency plan. (a) The contingency plan must describe the actions facility personnel must take to comply with §§ 265.51 and 265.56 in...

40 CFR 265.52 - Content of contingency plan.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Content of contingency plan. 265.52... DISPOSAL FACILITIES Contingency Plan and Emergency Procedures § 265.52 Content of contingency plan. (a) The contingency plan must describe the actions facility personnel must take to comply with §§ 265.51 and 265.56 in...

40 CFR 265.52 - Content of contingency plan.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Content of contingency plan. 265.52... DISPOSAL FACILITIES Contingency Plan and Emergency Procedures § 265.52 Content of contingency plan. (a) The contingency plan must describe the actions facility personnel must take to comply with §§ 265.51 and 265.56 in...

40 CFR 265.52 - Content of contingency plan.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Content of contingency plan. 265.52... DISPOSAL FACILITIES Contingency Plan and Emergency Procedures § 265.52 Content of contingency plan. (a) The contingency plan must describe the actions facility personnel must take to comply with §§ 265.51 and 265.56 in...

40 CFR 265.94 - Recordkeeping and reporting.

Code of Federal Regulations, 2012 CFR

2012-07-01

... required in § 265.92(e), and the evaluations required in § 265.93(b) throughout the active life of the... found in the upgradient wells, in accordance with § 265.93(c)(1). During the active life of the facility... requirements of § 265.93(d)(3), throughout the active life of the facility, and, for disposal facilities...

40 CFR 265.94 - Recordkeeping and reporting.

Code of Federal Regulations, 2010 CFR

2010-07-01

... required in § 265.92(e), and the evaluations required in § 265.93(b) throughout the active life of the... found in the upgradient wells, in accordance with § 265.93(c)(1). During the active life of the facility... requirements of § 265.93(d)(3), throughout the active life of the facility, and, for disposal facilities...

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-106

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Kelley, J. David (Technical Monitor)

2000-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-106. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-106 and the resulting effect on the Space Shuttle Program.

A Dynamic Analysis of Piezoelectric Strained Elements.

DTIC Science & Technology

1992-12-01

Type Quartz Crystal Plates ", IEEE SU- 29 (3), pp. 1 2 1 - 1 2 7 (1982). [107] L.K.Chau,High -frequency Long-wave Vibrations of Piezoelectric Ceramic ... Plate Excited with Voltage", Acta Acustica, 8 (5), pp. 300-310 (1983). [265] M.Ting-rong, "Forced Vibrations of Metal-Piezo- ceramic Thin Composite... ceramic and Metal Composite Thin Circular Plate with Different Diameter for Each Layer", Acta Acustica, 9 (5), pp. 298-310 (1984); Chinese J. Acoust., 2(3

47 CFR 87.265 - Administrative communications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false Administrative communications. 87.265 Section 87.265 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO... Stations § 87.265 Administrative communications. Domestic VHF aeronautical enroute stations authorized to...

Elements of adaptive optics based on metallized polymer films

NASA Astrophysics Data System (ADS)

Voliak, T. B.; Krasiuk, I. K.; Pashinin, P. P.

Results of an experimental study of the stability of metallized polymer films exposed to laser radiation at wavelengths of 1.06 and 10.6 microns are reported, and methods for fabricating variable-curvature mirrors from these films are discussed. Formulas are presented for calculating the shape of film mirrors as a function of the pressure acting on the film, mounting contour, and film properties. The performance of film mirrors is investigated experimentally in a pulsed CO2 laser with stable and unstable resonators.

40 CFR 265.223 - Containment system.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Containment system. 265.223 Section 265.223 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED... FACILITIES Surface Impoundments § 265.223 Containment system. All earthen dikes must have a protective cover...

40 CFR 265.231 - Air emission standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Air emission standards. 265.231 Section 265.231 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Surface Impoundments § 265.231 Air emission standards. The owner or operator shall...

40 CFR 265.231 - Air emission standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Air emission standards. 265.231 Section 265.231 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Surface Impoundments § 265.231 Air emission standards. The owner or operator shall...

40 CFR 265.231 - Air emission standards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Air emission standards. 265.231 Section 265.231 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Surface Impoundments § 265.231 Air emission standards. The owner or operator shall...

40 CFR 265.231 - Air emission standards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Air emission standards. 265.231 Section 265.231 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Surface Impoundments § 265.231 Air emission standards. The owner or operator shall...

40 CFR 265.223 - Containment system.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Containment system. 265.223 Section 265.223 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED... FACILITIES Surface Impoundments § 265.223 Containment system. All earthen dikes must have a protective cover...

7 CFR 65.265 - USDA.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 3 2014-01-01 2014-01-01 false USDA. 65.265 Section 65.265 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections..., AND GINSENG General Provisions Definitions § 65.265 USDA. USDA means the United States Department of...

7 CFR 65.265 - USDA.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 3 2011-01-01 2011-01-01 false USDA. 65.265 Section 65.265 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections..., AND GINSENG General Provisions Definitions § 65.265 USDA. USDA means the United States Department of...

7 CFR 65.265 - USDA.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false USDA. 65.265 Section 65.265 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections..., AND GINSENG General Provisions Definitions § 65.265 USDA. USDA means the United States Department of...

7 CFR 65.265 - USDA.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 3 2012-01-01 2012-01-01 false USDA. 65.265 Section 65.265 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections..., AND GINSENG General Provisions Definitions § 65.265 USDA. USDA means the United States Department of...

7 CFR 65.265 - USDA.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false USDA. 65.265 Section 65.265 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections..., AND GINSENG General Provisions Definitions § 65.265 USDA. USDA means the United States Department of...

39 CFR 265.4 - Inquiries.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Inquiries. 265.4 Section 265.4 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.4 Inquiries. Inquiries regarding the availability of Postal Service records should be directed to the appropriate records...

39 CFR 265.4 - Inquiries.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39 Postal Service 1 2011-07-01 2011-07-01 false Inquiries. 265.4 Section 265.4 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.4 Inquiries. Inquiries regarding the availability of Postal Service records should be directed to the appropriate records...

39 CFR 265.4 - Inquiries.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 39 Postal Service 1 2013-07-01 2013-07-01 false Inquiries. 265.4 Section 265.4 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.4 Inquiries. Inquiries regarding the availability of Postal Service records should be directed to the appropriate records...

39 CFR 265.4 - Inquiries.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 39 Postal Service 1 2012-07-01 2012-07-01 false Inquiries. 265.4 Section 265.4 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.4 Inquiries. Inquiries regarding the availability of Postal Service records should be directed to the appropriate records...

39 CFR 265.4 - Inquiries.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 39 Postal Service 1 2014-07-01 2014-07-01 false Inquiries. 265.4 Section 265.4 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.4 Inquiries. Inquiries regarding the availability of Postal Service records should be directed to the appropriate records...

40 CFR 265.202 - Air emission standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Air emission standards. 265.202 Section 265.202 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Tank Systems § 265.202 Air emission standards. The owner or operator shall manage all...

40 CFR 265.178 - Air emission standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Air emission standards. 265.178 Section 265.178 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Use and Management of Containers § 265.178 Air emission standards. The owner or...

40 CFR 265.178 - Air emission standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Air emission standards. 265.178 Section 265.178 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Use and Management of Containers § 265.178 Air emission standards. The owner or...

40 CFR 265.202 - Air emission standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Air emission standards. 265.202 Section 265.202 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Tank Systems § 265.202 Air emission standards. The owner or operator shall manage all...

40 CFR 265.202 - Air emission standards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Air emission standards. 265.202 Section 265.202 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Tank Systems § 265.202 Air emission standards. The owner or operator shall manage all...

40 CFR 265.178 - Air emission standards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Air emission standards. 265.178 Section 265.178 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Use and Management of Containers § 265.178 Air emission standards. The owner or...

40 CFR 265.178 - Air emission standards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Air emission standards. 265.178 Section 265.178 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Use and Management of Containers § 265.178 Air emission standards. The owner or...

40 CFR 265.202 - Air emission standards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Air emission standards. 265.202 Section 265.202 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Tank Systems § 265.202 Air emission standards. The owner or operator shall manage all...

45 CFR 156.265 - Enrollment process for qualified individuals.

Code of Federal Regulations, 2014 CFR

2014-10-01

....265 Section 156.265 Public Welfare Department of Health and Human Services REQUIREMENTS RELATING TO HEALTH CARE ACCESS HEALTH INSURANCE ISSUER STANDARDS UNDER THE AFFORDABLE CARE ACT, INCLUDING STANDARDS RELATED TO EXCHANGES Qualified Health Plan Minimum Certification Standards § 156.265 Enrollment process...

45 CFR 156.265 - Enrollment process for qualified individuals.

Code of Federal Regulations, 2012 CFR

2012-10-01

....265 Section 156.265 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS HEALTH INSURANCE ISSUER STANDARDS UNDER THE AFFORDABLE CARE ACT, INCLUDING STANDARDS RELATED TO EXCHANGES Qualified Health Plan Minimum Certification Standards § 156.265 Enrollment process...

45 CFR 156.265 - Enrollment process for qualified individuals.

Code of Federal Regulations, 2013 CFR

2013-10-01

....265 Section 156.265 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS HEALTH INSURANCE ISSUER STANDARDS UNDER THE AFFORDABLE CARE ACT, INCLUDING STANDARDS RELATED TO EXCHANGES Qualified Health Plan Minimum Certification Standards § 156.265 Enrollment process...

40 CFR 265.18 - Location standards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Location standards. 265.18 Section 265.18 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED... FACILITIES General Facility Standards § 265.18 Location standards. The placement of any hazardous waste in a...

DNA detection on ultrahigh-density optical fiber-based nanoarrays.

PubMed

Tam, Jenny M; Song, Linan; Walt, David R

2009-04-15

Nanoarrays for DNA detection were fabricated on etched nanofiber bundles based on recently developed techniques for microscale arrays. Two different-sized nanoarrays were created: one with 700 nm feature sizes and a 1 microm center-to-center pitch (approximately 1x10(6) array elements/mm(2)) and one with 300 nm feature sizes and a 500 nm center-to-center pitch (4.6x10(6) array elements/mm(2)). A random, multiplexed array composed of oligonucleotide-functionalized nanospheres was constructed and used for parallel detection and analysis of fluorescently labeled DNA targets. We have used these arrays to detect a variety of target sequences including Bacillus thuringiensis kurstaki and vaccina virus sequences, two potential biowarfare agents, as well as interleukin-2 sequences, an immune system modulator that has been used for the diagnosis of HIV.

Nicotine suppresses bone sialoprotein gene expression.

PubMed

Nakayama, Y; Mezawa, M; Araki, S; Sasaki, Y; Wang, S; Han, J; Li, X; Takai, H; Ogata, Y

2009-10-01

Tobacco smoking is a risk factor for periodontitis and osteoporosis. Nicotine is a major component of tobacco, and has been reported to inhibit proliferation and differentiation of osteoblasts. Bone sialoprotein (BSP) is a mineralized tissue-specific protein expressed by differentiated osteoblasts that appears to function in the initial mineralization of bone. The purpose of this study was to determine the effects of nicotine on bone metabolism. We used rat osteobast-like UMR106 and ROS 17/2.8 cells and rat stromal bone marrow RBMC-D8 cells. To determine the molecular basis of the transcriptional regulation of the BSP gene by nicotine, we conducted Northern hybridization, transient transfection analyses with chimeric constructs of the BSP gene promoter linked to a luciferase reporter gene and gel mobility shift assays. Nicotine (250 microg/mL) decreased the BSP mRNA levels at 12 and 24 h in UMR106 and ROS 17/2.8 cells. From transient transfection assays using various sized BSP promoter-luciferase constructs, nicotine decreased the luciferase activities of the construct, including the promoter sequence nucleotides -116 to +60, in UMR106 and RBMC-D8 cells. Nicotine decreased the nuclear protein binding to the cAMP response element (CRE), fibroblast growth factor 2 response element (FRE) and homeodomain protein-binding site (HOX) at 12 and 24 h. This study indicates that nicotine suppresses BSP transcription mediated through CRE, FRE and HOX elements in the proximal promoter of the rat BSP gene.

Solid phase extraction of rare earth elements in seawater and estuarine water with 4-(2-thiazolylazo) resorcinol immobilized Chromosorb 106 for determination by inductively coupled plasma mass spectrometry

PubMed Central

Zereen, Fahmida; Yilmaz, Vedat; Arslan, Zikri

2013-01-01

A solid phase preconcentration method has been developed using new chelating resin prepared by immobilization of 4-(2-thiazolylazo) resorcinol (TAR) on Chromosorb 106. The method was optimized for determination of rare earth elements (REEs) in seawater and estuarine water samples by inductively coupled plasma mass spectrometry (ICP-MS). The effects of various experimental parameters, such as load pH, eluent concentration, sample and eluent flow rates were examined to find the optimum operating conditions. The REEs were quantitatively retained from saline solutions on a minicolumn Chromosorb 106-TAR resin at pH 5.0 and then eluted with 1.0 mL of 1% (v/v) HNO3. The resin possesses large sorption capacity for REEs ranging from 81.1 µmol g−1 for Lu and 108 µmol g−1 for Nd. Detection limits (3s) varied between 0.06 ng L−1 for Pr to 0.31 for Ce for preconcentration of 5.0 mL blank solutions (pH 5.0). The relative standard deviation for triplicate measurements was less than 5% at 0.1 µg L−1 level. The method was validated by analysis Nearshore seawater certified reference material (CASS–4). The elemental results were comparable with the values reported in literature. The method was verified by analysis of spiked and unspiked coastal seawater and estuarine water samples. PMID:24000264

Solid phase extraction of rare earth elements in seawater and estuarine water with 4-(2-thiazolylazo) resorcinol immobilized Chromosorb 106 for determination by inductively coupled plasma mass spectrometry.

PubMed

Zereen, Fahmida; Yilmaz, Vedat; Arslan, Zikri

2013-09-01

A solid phase preconcentration method has been developed using new chelating resin prepared by immobilization of 4-(2-thiazolylazo) resorcinol (TAR) on Chromosorb 106. The method was optimized for determination of rare earth elements (REEs) in seawater and estuarine water samples by inductively coupled plasma mass spectrometry (ICP-MS). The effects of various experimental parameters, such as load pH, eluent concentration, sample and eluent flow rates were examined to find the optimum operating conditions. The REEs were quantitatively retained from saline solutions on a minicolumn Chromosorb 106-TAR resin at pH 5.0 and then eluted with 1.0 mL of 1% (v/v) HNO 3 . The resin possesses large sorption capacity for REEs ranging from 81.1 µmol g -1 for Lu and 108 µmol g -1 for Nd. Detection limits (3s) varied between 0.06 ng L -1 for Pr to 0.31 for Ce for preconcentration of 5.0 mL blank solutions (pH 5.0). The relative standard deviation for triplicate measurements was less than 5% at 0.1 µg L -1 level. The method was validated by analysis Nearshore seawater certified reference material (CASS-4). The elemental results were comparable with the values reported in literature. The method was verified by analysis of spiked and unspiked coastal seawater and estuarine water samples.

Emissions of mercury in Southern Africa derived from long-term observations at Cape Point, South Africa

NASA Astrophysics Data System (ADS)

Brunke, E.-G.; Ebinghaus, R.; Kock, H. H.; Labuschagne, C.; Slemr, F.

2012-05-01

Mercury emissions in South Africa have so far been estimated only by a bottom-up approach from activities and emission factors for different processes. In this paper we derive GEM/CO (GEM being gaseous elemental mercury, Hg0), GEM/CO2, GEM/CH4, CO/CO2, CH4/CO2, and CH4/CO emission ratios from plumes observed during long-term monitoring of these species at Cape Point between March 2007 and December 2009. The average observed GEM/CO, GEM/CO2, GEM/CH4, CO/CO2, CH4/CO2, and CH4/CO emission ratios were 2.40 ± 2.65 pg m-3 ppb-1 (n = 47), 62.7 ± 80.2 pg m-3 ppb-1 (n = 44), 3.61 ± 4.66 pg m-3 ppb-1 (n = 46), 35.6 ± 25.4 ppb ppm-1 (n = 52), 20.2 ± 15.5 ppb ppm-1 (n=48), and 0.876 ± 1.106 ppb ppm-1 (n=42), respectively. The observed CO/CO2, CH4/CO2, and CH4/CO emission ratios agree within the combined uncertainties of the observations and emissions with the ratios calculated from EDGAR (version 4.2) CO2, CO, and CH4 inventories for South Africa and Southern Africa (South Africa, Lesotho, Swaziland, Namibia, Botswana, Zimbabwe, and Mozambique) in 2007 and 2008 (inventories for 2009 are not available yet). Total elemental mercury emission of 13.1, 15.2, and 16.1 t Hg yr-1 are estimated independently using the GEM/CO, GEM/CO2, and GEM/CH4 emission ratios and the annual mean CO, CO2, and CH4 emissions, respectively, of South Africa in 2007 and 2008. The average of these independent estimates of 14.8 ± 1.5 t GEM yr-1 is much less than the total emission of 257 t Hg yr-1 from older inventories. Considering that emission of GEM represents only 50-78% of all mercury emissions, our estimates come close to the total mercury emission estimates ranging between 40-50 t Hg yr-1 from more recent inventories.

40 CFR 265.16 - Personnel training.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Personnel training. 265.16 Section 265... FACILITIES General Facility Standards § 265.16 Personnel training. (a)(1) Facility personnel must successfully complete a program of classroom instruction or on-the-job training that teaches them to perform...

39 CFR 265.10 - Annual report.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 39 Postal Service 1 2012-07-01 2012-07-01 false Annual report. 265.10 Section 265.10 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.10 Annual report. A report concerning the administration of the Freedom of Information Act and this part...

39 CFR 265.10 - Annual report.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Annual report. 265.10 Section 265.10 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.10 Annual report. A report concerning the administration of the Freedom of Information Act and this part...

39 CFR 265.3 - Responsibility.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 39 Postal Service 1 2013-07-01 2013-07-01 false Responsibility. 265.3 Section 265.3 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.3 Responsibility. (a) Custodian. Official records are in the custody of the postmaster or other head of a facility...

39 CFR 265.10 - Annual report.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 39 Postal Service 1 2013-07-01 2013-07-01 false Annual report. 265.10 Section 265.10 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.10 Annual report. A report concerning the administration of the Freedom of Information Act and this part...

39 CFR 265.10 - Annual report.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39 Postal Service 1 2011-07-01 2011-07-01 false Annual report. 265.10 Section 265.10 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.10 Annual report. A report concerning the administration of the Freedom of Information Act and this part...

39 CFR 265.3 - Responsibility.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Responsibility. 265.3 Section 265.3 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.3 Responsibility. (a) Custodian. Official records are in the custody of the postmaster or other head of a facility...

39 CFR 265.10 - Annual report.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 39 Postal Service 1 2014-07-01 2014-07-01 false Annual report. 265.10 Section 265.10 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.10 Annual report. A report concerning the administration of the Freedom of Information Act and this part...

39 CFR 265.3 - Responsibility.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 39 Postal Service 1 2014-07-01 2014-07-01 false Responsibility. 265.3 Section 265.3 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.3 Responsibility. (a) Custodian. Official records are in the custody of the postmaster or other head of a facility...

39 CFR 265.3 - Responsibility.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 39 Postal Service 1 2012-07-01 2012-07-01 false Responsibility. 265.3 Section 265.3 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.3 Responsibility. (a) Custodian. Official records are in the custody of the postmaster or other head of a facility...

39 CFR 265.3 - Responsibility.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39 Postal Service 1 2011-07-01 2011-07-01 false Responsibility. 265.3 Section 265.3 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.3 Responsibility. (a) Custodian. Official records are in the custody of the postmaster or other head of a facility...

15 CFR 265.32 - Trespassing.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Trespassing. 265.32 Section 265.32 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.32 Trespassing. No...

15 CFR 265.32 - Trespassing.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Trespassing. 265.32 Section 265.32 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.32 Trespassing. No...

15 CFR 265.32 - Trespassing.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Trespassing. 265.32 Section 265.32 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.32 Trespassing. No...

15 CFR 265.32 - Trespassing.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Trespassing. 265.32 Section 265.32 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.32 Trespassing. No...

15 CFR 265.32 - Trespassing.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Trespassing. 265.32 Section 265.32 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.32 Trespassing. No...

40 CFR 265.254 - Design and operating requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Design and operating requirements. 265.254 Section 265.254 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Waste Piles § 265.254 Design and operating requirements. The owner or operator of each...

40 CFR 265.14 - Security.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Security. 265.14 Section 265.14... Facility Standards § 265.14 Security. (a) The owner or operator must prevent the unknowing entry, and...) for discussion of security requirements at disposal facilities during the post-closure care period...

40 CFR 265.14 - Security.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Security. 265.14 Section 265.14... Facility Standards § 265.14 Security. (a) The owner or operator must prevent the unknowing entry, and...) for discussion of security requirements at disposal facilities during the post-closure care period...

40 CFR 265.14 - Security.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Security. 265.14 Section 265.14... Facility Standards § 265.14 Security. (a) The owner or operator must prevent the unknowing entry, and...) for discussion of security requirements at disposal facilities during the post-closure care period...

40 CFR 265.14 - Security.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Security. 265.14 Section 265.14... Facility Standards § 265.14 Security. (a) The owner or operator must prevent the unknowing entry, and...) for discussion of security requirements at disposal facilities during the post-closure care period...

40 CFR 265.148 - Incapacity of owners or operators, guarantors, or financial institutions.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., guarantors, or financial institutions. 265.148 Section 265.148 Protection of Environment ENVIRONMENTAL... HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Financial Requirements § 265.148 Incapacity of owners or operators, guarantors, or financial institutions. (a) An owner or operator must notify the...

14 CFR 26.5 - Applicability table.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Applicability table. 26.5 Section 26.5... AIRWORTHINESS AND SAFETY IMPROVEMENTS FOR TRANSPORT CATEGORY AIRPLANES General § 26.5 Applicability table. Table... Subpart B EAPAS/FTS Subpart C widespread fatigue damage Subpart D fuel tankflammability Subpart E...

14 CFR 26.5 - Applicability table.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Applicability table. 26.5 Section 26.5... AIRWORTHINESS AND SAFETY IMPROVEMENTS FOR TRANSPORT CATEGORY AIRPLANES General § 26.5 Applicability table. Table... Subpart B EAPAS/FTS Subpart C widespread fatigue damage Subpart D fuel tankflammability Subpart E...

14 CFR 26.5 - Applicability table.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Applicability table. 26.5 Section 26.5... AIRWORTHINESS AND SAFETY IMPROVEMENTS FOR TRANSPORT CATEGORY AIRPLANES General § 26.5 Applicability table. Table... Subpart B EAPAS/FTS Subpart C widespread fatigue damage Subpart D fuel tankflammability Subpart E...

40 CFR 35.265 - Maximum federal share.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Maximum federal share. 35.265 Section 35.265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE....265 Maximum federal share. The Regional Administrator may provide up to 60 percent of the approved...

In vivo detection of amyloid plaques in the mouse brain using the near-infrared fluorescence probe THK-265.

PubMed

Okamura, Nobuyuki; Mori, Masanori; Furumoto, Shozo; Yoshikawa, Takeo; Harada, Ryuichi; Ito, Satoshi; Fujikawa, Yosuke; Arai, Hiroyuki; Yanai, Kazuhiko; Kudo, Yukitsuka

2011-01-01

Noninvasive detection of amyloid-β (Aβ) deposits in the brain would be beneficial for an early and presymptomatic diagnosis of Alzheimer's disease (AD). We developed THK-265 as a candidate near-infrared fluorescence (NIRF) probe for the in vivo detection of amyloid deposits in the brain. The maximal emission wavelength of THK-265 was greater than 650nm and it showed high quantum yield and molar absorption coefficients. A fluorescence binding assay showed its high binding affinity to Aβ fibrils (Kd = 97 nM). THK-265 clearly stained amyloid plaques in AD neocortical brain sections and showed a moderate log p value (1.8). After intravenous administration of THK-265 in amyloid-β protein precursor (AβPP) transgenic mice, amyloid deposits in the brain were clearly labeled with THK-265. Furthermore, in vivo NIRF imaging demonstrated significantly higher fluorescence intensity in the brains of AβPP transgenic mice than in those of wild-type mice. As THK-265 showed profound hyperchromic effect upon binding to Aβ fibrils, good discrimination between AβPP transgenic and wild-type mice was demonstrated even early after THK-265 administration. Furthermore, the fluorescence intensity of THK-265 correlated with amyloid plaque burden in the brains of AβPP transgenic mice. These findings strongly support the usefulness of THK-265 as an NIRF imaging probe for the noninvasive measurement of brain amyloid load.

Distribution of arsenic and mercury in lime spray dryer ash

DOE Office of Scientific and Technical Information (OSTI.GOV)

Panuwat Taerakul; Ping Sun; Danold W. Golightly

The partitioning of As and Hg in various components of lime spray dryer (LSD) ash samples from a coal-fired boiler was characterized to better understand the form and fate of these elements in flue gas desulfurization byproducts. LSD ash samples, collected from the McCracken Power Plant on the Ohio State University campus, were separated by a 140-mesh (106 {mu}m) sieve into two fractions: a fly-ash-/unburned-carbon-enriched fraction (> 106 {mu}m) and a calcium-enriched fraction (< 106 {mu}m). Unburned carbon and fly ash in the material > 106 {mu}m were subsequently separated by density using a lithium heteropolytungstate solution. The concentrations ofmore » As and Hg were significant in all fractions. The level of As was consistently greater in the calcium-enriched fraction, while Hg was evenly distributed in all components of LSD ash. Specific surface area was an important factor controlling the distribution of Hg in the different components of LSD ash, but not for As. Comparing the LSD ash data to samples collected from the economizer suggests that As was effectively captured by fly ash at 600{sup o}C, while Hg was not. Leaching tests demonstrated that As and Hg were more stable in the calcium-enriched fraction than in the fly-ash- or carbon-enriched fractions, potentially because of the greater pH of the leachate and subsequently greater stability of small amounts of calcium solids containing trace elements in these fractions. 37 refs., 8 figs., 2 tabs.« less

15 CFR 265.33 - Preservation of property.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Preservation of property. 265.33 Section 265.33 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.33 Preservation of...

40 CFR 265.116 - Survey plat.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Survey plat. 265.116 Section 265.116... and Post-Closure § 265.116 Survey plat. No later than the submission of the certification of closure..., or the authority with jurisdiction over local land use, and to the Regional Administrator, a survey...

40 CFR 265.116 - Survey plat.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Survey plat. 265.116 Section 265.116... and Post-Closure § 265.116 Survey plat. No later than the submission of the certification of closure..., or the authority with jurisdiction over local land use, and to the Regional Administrator, a survey...

40 CFR 265.116 - Survey plat.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Survey plat. 265.116 Section 265.116... and Post-Closure § 265.116 Survey plat. No later than the submission of the certification of closure..., or the authority with jurisdiction over local land use, and to the Regional Administrator, a survey...

40 CFR 265.116 - Survey plat.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Survey plat. 265.116 Section 265.116... and Post-Closure § 265.116 Survey plat. No later than the submission of the certification of closure..., or the authority with jurisdiction over local land use, and to the Regional Administrator, a survey...

40 CFR 265.116 - Survey plat.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Survey plat. 265.116 Section 265.116... and Post-Closure § 265.116 Survey plat. No later than the submission of the certification of closure..., or the authority with jurisdiction over local land use, and to the Regional Administrator, a survey...

39 CFR 265.8 - Business information; procedures for predisclosure notification to submitters.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 39 Postal Service 1 2014-07-01 2014-07-01 false Business information; procedures for predisclosure notification to submitters. 265.8 Section 265.8 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.8 Business information; procedures for predisclosure notification to...

39 CFR 265.8 - Business information; procedures for predisclosure notification to submitters.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Business information; procedures for predisclosure notification to submitters. 265.8 Section 265.8 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.8 Business information; procedures for predisclosure notification to...

39 CFR 265.2 - Policy.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39 Postal Service 1 2011-07-01 2011-07-01 false Policy. 265.2 Section 265.2 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.2 Policy. (a) It is the policy of the Postal Service to make its official records available to the public to the maximum...

39 CFR 265.8 - Business information; procedures for predisclosure notification to submitters.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 39 Postal Service 1 2012-07-01 2012-07-01 false Business information; procedures for predisclosure notification to submitters. 265.8 Section 265.8 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.8 Business information; procedures for predisclosure notification to...

39 CFR 265.5 - Public reading rooms.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39 Postal Service 1 2011-07-01 2011-07-01 false Public reading rooms. 265.5 Section 265.5 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.5 Public reading rooms. The Library of the Postal Service Headquarters, 475 L'Enfant Plaza SW, Washington, DC 20260...

39 CFR 265.11 - Compliance with subpoena duces tecum, court orders, and summonses.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., and summonses. 265.11 Section 265.11 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.11 Compliance with subpoena duces tecum, court orders, and summonses... release medical information, in response to proper requests and upon competent medical advice, in...

39 CFR 265.5 - Public reading rooms.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Public reading rooms. 265.5 Section 265.5 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.5 Public reading rooms. The Library of the Postal Service Headquarters, 475 L'Enfant Plaza SW, Washington, DC 20260...

39 CFR 265.5 - Public reading rooms.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 39 Postal Service 1 2014-07-01 2014-07-01 false Public reading rooms. 265.5 Section 265.5 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.5 Public reading rooms. The Library of the Postal Service Headquarters, 475 L'Enfant Plaza SW, Washington, DC 20260...

39 CFR 265.11 - Compliance with subpoena duces tecum, court orders, and summonses.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., and summonses. 265.11 Section 265.11 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.11 Compliance with subpoena duces tecum, court orders, and summonses... release medical information, in response to proper requests and upon competent medical advice, in...

39 CFR 265.11 - Compliance with subpoena duces tecum, court orders, and summonses.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., and summonses. 265.11 Section 265.11 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.11 Compliance with subpoena duces tecum, court orders, and summonses... release medical information, in response to proper requests and upon competent medical advice, in...

39 CFR 265.11 - Compliance with subpoena duces tecum, court orders, and summonses.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., and summonses. 265.11 Section 265.11 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.11 Compliance with subpoena duces tecum, court orders, and summonses... release medical information, in response to proper requests and upon competent medical advice, in...

39 CFR 265.2 - Policy.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Policy. 265.2 Section 265.2 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.2 Policy. (a) It is the policy of the Postal Service to make its official records available to the public to the maximum...

39 CFR 265.8 - Business information; procedures for predisclosure notification to submitters.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39 Postal Service 1 2011-07-01 2011-07-01 false Business information; procedures for predisclosure notification to submitters. 265.8 Section 265.8 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.8 Business information; procedures for predisclosure notification to...

39 CFR 265.8 - Business information; procedures for predisclosure notification to submitters.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 39 Postal Service 1 2013-07-01 2013-07-01 false Business information; procedures for predisclosure notification to submitters. 265.8 Section 265.8 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.8 Business information; procedures for predisclosure notification to...

39 CFR 265.2 - Policy.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 39 Postal Service 1 2013-07-01 2013-07-01 false Policy. 265.2 Section 265.2 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.2 Policy. (a) It is the policy of the Postal Service to make its official records available to the public to the maximum...

39 CFR 265.2 - Policy.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 39 Postal Service 1 2012-07-01 2012-07-01 false Policy. 265.2 Section 265.2 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.2 Policy. (a) It is the policy of the Postal Service to make its official records available to the public to the maximum...

39 CFR 265.5 - Public reading rooms.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 39 Postal Service 1 2012-07-01 2012-07-01 false Public reading rooms. 265.5 Section 265.5 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.5 Public reading rooms. The Library of the Postal Service Headquarters, 475 L'Enfant Plaza SW, Washington, DC 20260...

39 CFR 265.5 - Public reading rooms.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 39 Postal Service 1 2013-07-01 2013-07-01 false Public reading rooms. 265.5 Section 265.5 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.5 Public reading rooms. The Library of the Postal Service Headquarters, 475 L'Enfant Plaza SW, Washington, DC 20260...

39 CFR 265.11 - Compliance with subpoena duces tecum, court orders, and summonses.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., and summonses. 265.11 Section 265.11 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.11 Compliance with subpoena duces tecum, court orders, and summonses... release medical information, in response to proper requests and upon competent medical advice, in...

39 CFR 265.2 - Policy.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 39 Postal Service 1 2014-07-01 2014-07-01 false Policy. 265.2 Section 265.2 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.2 Policy. (a) It is the policy of the Postal Service to make its official records available to the public to the maximum...

40 CFR 265.119 - Post-closure notices.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 265.119 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED... zoning authority, or the authority with jurisdiction over local land use, and to the Regional... required by §§ 265.116 and 265.119(a) have been filed with the local zoning authority or the authority with...

40 CFR 265.119 - Post-closure notices.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 265.119 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED... zoning authority, or the authority with jurisdiction over local land use, and to the Regional... required by §§ 265.116 and 265.119(a) have been filed with the local zoning authority or the authority with...

15 CFR 265.41 - Gambling.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Gambling. 265.41 Section 265.41..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.41 Gambling. No... gambling devices, the conduct of lotteries or pools, or in the selling or purchasing of numbers tickets, or...

40 CFR 265.1054 - Standards: Pressure relief devices in gas/vapor service.

Code of Federal Regulations, 2010 CFR

2010-07-01

... gas/vapor service. 265.1054 Section 265.1054 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... TREATMENT, STORAGE, AND DISPOSAL FACILITIES Air Emission Standards for Equipment Leaks § 265.1054 Standards: Pressure relief devices in gas/vapor service. (a) Except during pressure releases, each pressure relief...

15 CFR 265.41 - Gambling.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Gambling. 265.41 Section 265.41..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.41 Gambling. No person shall participate on the site in games for money or other property, or in the operation of...

15 CFR 265.41 - Gambling.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Gambling. 265.41 Section 265.41..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.41 Gambling. No... gambling devices, the conduct of lotteries or pools, or in the selling or purchasing of numbers tickets, or...

15 CFR 265.41 - Gambling.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Gambling. 265.41 Section 265.41..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.41 Gambling. No... gambling devices, the conduct of lotteries or pools, or in the selling or purchasing of numbers tickets, or...

15 CFR 265.41 - Gambling.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Gambling. 265.41 Section 265.41..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.41 Gambling. No... gambling devices, the conduct of lotteries or pools, or in the selling or purchasing of numbers tickets, or...

40 CFR 265.1088 - Standards: Closed-vent systems and control devices.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Standards: Closed-vent systems and control devices. 265.1088 Section 265.1088 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Containers § 265.1088 Standards: Closed-vent systems and control devices. (a) This section applies to each...

15 CFR 265.42 - Photography for advertising or commercial purposes; advertising and soliciting.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Photography for advertising or commercial purposes; advertising and soliciting. 265.42 Section 265.42 Commerce and Foreign Trade Regulations... COLLINS, COLORADO Buildings and Grounds § 265.42 Photography for advertising or commercial purposes...

12 CFR 265.2 - Delegation of functions generally.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 3 2011-01-01 2011-01-01 false Delegation of functions generally. 265.2 Section 265.2 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM RULES REGARDING DELEGATION OF AUTHORITY § 265.2 Delegation of functions generally. (a) The...

40 CFR 265.1033 - Standards: Closed-vent systems and control devices.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Standards: Closed-vent systems and control devices. 265.1033 Section 265.1033 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... total carbon working capacity -established as a requirement of § 265.1035(b)(4)(iii)(G), whichever is...

39 CFR Appendix A to Part 265 - Fees for Computer Searches

Code of Federal Regulations, 2013 CFR

2013-07-01

... 39 Postal Service 1 2013-07-01 2013-07-01 false Fees for Computer Searches A Appendix A to Part 265 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION Pt. 265, App. A Appendix A to Part 265—Fees for Computer Searches When requested information must be...

39 CFR Appendix A to Part 265 - Fees for Computer Searches

Code of Federal Regulations, 2012 CFR

2012-07-01

... 39 Postal Service 1 2012-07-01 2012-07-01 false Fees for Computer Searches A Appendix A to Part 265 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION Pt. 265, App. A Appendix A to Part 265—Fees for Computer Searches When requested information must be...

39 CFR 265.1 - Purpose and scope.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 39 Postal Service 1 2012-07-01 2012-07-01 false Purpose and scope. 265.1 Section 265.1 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.1... section 552 of title 5, U.S.C., the “Freedom of Information Act,” insofar as it applies to the Postal...

39 CFR 265.1 - Purpose and scope.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 39 Postal Service 1 2013-07-01 2013-07-01 false Purpose and scope. 265.1 Section 265.1 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.1... section 552 of title 5, U.S.C., the “Freedom of Information Act,” insofar as it applies to the Postal...

39 CFR Appendix A to Part 265 - Fees for Computer Searches

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39 Postal Service 1 2011-07-01 2011-07-01 false Fees for Computer Searches A Appendix A to Part 265 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION Pt. 265, App. A Appendix A to Part 265—Fees for Computer Searches When requested information must be...

39 CFR 265.1 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Purpose and scope. 265.1 Section 265.1 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.1... section 552 of title 5, U.S.C., the “Freedom of Information Act,” insofar as it applies to the Postal...

39 CFR 265.7 - Procedure for inspection and copying of records.

Code of Federal Regulations, 2014 CFR

2014-07-01

.... 265.7 Section 265.7 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.7 Procedure for inspection and copying of records. (a) Submission of requests... Service record shall be in writing and bear the caption “Freedom of Information Act Request” or otherwise...

39 CFR 265.7 - Procedure for inspection and copying of records.

Code of Federal Regulations, 2013 CFR

2013-07-01

.... 265.7 Section 265.7 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.7 Procedure for inspection and copying of records. (a) Submission of requests... Service record shall be in writing and bear the caption “Freedom of Information Act Request” or otherwise...

39 CFR 265.7 - Procedure for inspection and copying of records.

Code of Federal Regulations, 2011 CFR

2011-07-01

.... 265.7 Section 265.7 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.7 Procedure for inspection and copying of records. (a) Submission of requests... Service record shall be in writing and bear the caption “Freedom of Information Act Request” or otherwise...

39 CFR 265.1 - Purpose and scope.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39 Postal Service 1 2011-07-01 2011-07-01 false Purpose and scope. 265.1 Section 265.1 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.1... section 552 of title 5, U.S.C., the “Freedom of Information Act,” insofar as it applies to the Postal...

39 CFR 265.12 - Demands for testimony or records in certain legal proceedings.

Code of Federal Regulations, 2014 CFR

2014-07-01

... proceedings. 265.12 Section 265.12 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.12 Demands for testimony or records in certain legal proceedings. (a) Scope...: (i) Records contained in the files of the Postal Service; (ii) Information relating to records...

39 CFR 265.12 - Demands for testimony or records in certain legal proceedings.

Code of Federal Regulations, 2012 CFR

2012-07-01

... proceedings. 265.12 Section 265.12 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.12 Demands for testimony or records in certain legal proceedings. (a) Scope...: (i) Records contained in the files of the Postal Service; (ii) Information relating to records...

39 CFR 265.12 - Demands for testimony or records in certain legal proceedings.

Code of Federal Regulations, 2013 CFR

2013-07-01

... proceedings. 265.12 Section 265.12 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.12 Demands for testimony or records in certain legal proceedings. (a) Scope...: (i) Records contained in the files of the Postal Service; (ii) Information relating to records...

39 CFR 265.1 - Purpose and scope.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 39 Postal Service 1 2014-07-01 2014-07-01 false Purpose and scope. 265.1 Section 265.1 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.1... section 552 of title 5, U.S.C., the “Freedom of Information Act,” insofar as it applies to the Postal...

39 CFR 265.12 - Demands for testimony or records in certain legal proceedings.

Code of Federal Regulations, 2011 CFR

2011-07-01

... proceedings. 265.12 Section 265.12 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.12 Demands for testimony or records in certain legal proceedings. (a) Scope...: (i) Records contained in the files of the Postal Service; (ii) Information relating to records...

39 CFR Appendix A to Part 265 - Fees for Computer Searches

Code of Federal Regulations, 2014 CFR

2014-07-01

... 39 Postal Service 1 2014-07-01 2014-07-01 false Fees for Computer Searches A Appendix A to Part 265 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION Pt. 265, App. A Appendix A to Part 265—Fees for Computer Searches When requested information must be...

39 CFR 265.7 - Procedure for inspection and copying of records.

Code of Federal Regulations, 2012 CFR

2012-07-01

.... 265.7 Section 265.7 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.7 Procedure for inspection and copying of records. (a) Submission of requests... Service record shall be in writing and bear the caption “Freedom of Information Act Request” or otherwise...

39 CFR 265.12 - Demands for testimony or records in certain legal proceedings.

Code of Federal Regulations, 2010 CFR

2010-07-01

... proceedings. 265.12 Section 265.12 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.12 Demands for testimony or records in certain legal proceedings. (a) Scope...: (i) Records contained in the files of the Postal Service; (ii) Information relating to records...

39 CFR Appendix A to Part 265 - Fees for Computer Searches

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Fees for Computer Searches A Appendix A to Part 265 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION Pt. 265, App. A Appendix A to Part 265—Fees for Computer Searches When requested information must be...

40 CFR 265.255 - Action leakage rates.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Action leakage rates. 265.255 Section... FACILITIES Waste Piles § 265.255 Action leakage rates. (a) The owner or operator of waste pile units subject to § 265.254 must submit a proposed action leakage rate to the Regional Administrator when submitting...

40 CFR 265.302 - Action leakage rate.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Action leakage rate. 265.302 Section... FACILITIES Landfills § 265.302 Action leakage rate. (a) The owner or operator of landfill units subject to § 265.301(a) must submit a proposed action leakage rate to the Regional Administrator when submitting...

40 CFR 265.222 - Action leakage rate.

Code of Federal Regulations, 2010 CFR

2010-07-01

... to § 265.221(a). The action leakage rate is the maximum design flow rate that the leak detection... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Action leakage rate. 265.222 Section... FACILITIES Surface Impoundments § 265.222 Action leakage rate. (a) The owner or operator of surface...

27 CFR 26.265 - Determination of tax on articles.

Code of Federal Regulations, 2012 CFR

2012-04-01

... articles. 26.265 Section 26.265 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS LIQUORS AND ARTICLES FROM PUERTO RICO AND THE VIRGIN ISLANDS Procedure at Port of Entry From the Virgin Islands § 26.265 Determination of tax on articles. Where articles...

27 CFR 26.265 - Determination of tax on articles.

Code of Federal Regulations, 2014 CFR

2014-04-01

... articles. 26.265 Section 26.265 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL LIQUORS AND ARTICLES FROM PUERTO RICO AND THE VIRGIN ISLANDS Procedure at Port of Entry From the Virgin Islands § 26.265 Determination of tax on articles. Where articles...

27 CFR 26.265 - Determination of tax on articles.

Code of Federal Regulations, 2010 CFR

2010-04-01

... articles. 26.265 Section 26.265 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS LIQUORS AND ARTICLES FROM PUERTO RICO AND THE VIRGIN ISLANDS Procedure at Port of Entry From the Virgin Islands § 26.265 Determination of tax on articles. Where articles...

26 CFR 1.265-2 - Interest relating to tax exempt income.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 26 Internal Revenue 3 2011-04-01 2011-04-01 false Interest relating to tax exempt income. 1.265-2 Section 1.265-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Items Not Deductible § 1.265-2 Interest relating to tax...

25 CFR 265.1 - Definition of roadless area.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 1 2014-04-01 2014-04-01 false Definition of roadless area. 265.1 Section 265.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HERITAGE PRESERVATION ESTABLISHMENT OF ROADLESS AND WILD AREAS ON INDIAN RESERVATIONS § 265.1 Definition of roadless area. A roadless area has been defined...

25 CFR 265.1 - Definition of roadless area.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 1 2013-04-01 2013-04-01 false Definition of roadless area. 265.1 Section 265.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HERITAGE PRESERVATION ESTABLISHMENT OF ROADLESS AND WILD AREAS ON INDIAN RESERVATIONS § 265.1 Definition of roadless area. A roadless area has been defined...

12 CFR 265.8 - Functions delegated to the Staff Director of the Division of International Finance.

Code of Federal Regulations, 2014 CFR

2014-01-01

... the Division of International Finance. 265.8 Section 265.8 Banks and Banking FEDERAL RESERVE SYSTEM... AUTHORITY § 265.8 Functions delegated to the Staff Director of the Division of International Finance. The Board's Staff Director of the Division of International Finance (or the Director's delegee) is...

12 CFR 265.8 - Functions delegated to the Staff Director of the Division of International Finance.

Code of Federal Regulations, 2012 CFR

2012-01-01

... the Division of International Finance. 265.8 Section 265.8 Banks and Banking FEDERAL RESERVE SYSTEM... AUTHORITY § 265.8 Functions delegated to the Staff Director of the Division of International Finance. The Board's Staff Director of the Division of International Finance (or the Director's delegee) is...

12 CFR 265.8 - Functions delegated to the Staff Director of the Division of International Finance.

Code of Federal Regulations, 2013 CFR

2013-01-01

... the Division of International Finance. 265.8 Section 265.8 Banks and Banking FEDERAL RESERVE SYSTEM... AUTHORITY § 265.8 Functions delegated to the Staff Director of the Division of International Finance. The Board's Staff Director of the Division of International Finance (or the Director's delegee) is...

15 CFR 265.51 - Penalties-other laws.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Penalties-other laws. 265.51 Section..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Penalties § 265.51 Penalties—other laws. Except with respect to the laws of the State of Maryland and the State of Colorado assimilated by § 265.5 or...

15 CFR 265.31 - Closing the site.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Closing the site. 265.31 Section 265..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.31 Closing the site... may be closed to the public in emergency situations and at such other times as may be necessary for...

40 CFR 265.316 - Disposal of small containers of hazardous waste in overpacked drums (lab packs).

Code of Federal Regulations, 2010 CFR

2010-07-01

... OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Landfills § 265.316 Disposal of small containers of hazardous waste in overpacked drums (lab packs). Small containers of hazardous waste... hazardous waste in overpacked drums (lab packs). 265.316 Section 265.316 Protection of Environment...

8 CFR 265.1 - Forms.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Forms. 265.1 Section 265.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS NOTICES OF ADDRESS § 265.1 Forms. Except... under section 262 of the Act shall report each change of address and new address within 10 days on Form...

45 CFR 265.6 - Must States file reports electronically?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true Must States file reports electronically? 265.6 Section 265.6 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES DATA COLLECTION AND REPORTING REQUIREMENTS § 265.6...

40 CFR 265.228 - Closure and post-closure care.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Closure and post-closure care. 265.228... DISPOSAL FACILITIES Surface Impoundments § 265.228 Closure and post-closure care. (a) At closure, the owner... impoundment and provide post-closure care for a landfill under subpart G and § 265.310, including the...

40 CFR 265.228 - Closure and post-closure care.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Closure and post-closure care. 265.228... DISPOSAL FACILITIES Surface Impoundments § 265.228 Closure and post-closure care. (a) At closure, the owner... impoundment and provide post-closure care for a landfill under subpart G and § 265.310, including the...

12 CFR 26.5 - Small market share exemption.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Small market share exemption. 26.5 Section 26.5 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY MANAGEMENT OFFICIAL INTERLOCKS § 26.5 Small market share exemption. (a) Exemption. A management interlock that is prohibited by § 26.3...

45 CFR 265.4 - When are quarterly reports due?

Code of Federal Regulations, 2010 CFR

2010-10-01

... COLLECTION AND REPORTING REQUIREMENTS § 265.4 When are quarterly reports due? (a) Each State must file the TANF Data Report and the TANF Financial Report (or, as applicable, the Territorial Financial Report... 45 Public Welfare 2 2010-10-01 2010-10-01 false When are quarterly reports due? 265.4 Section 265...

20 CFR 416.265 - Requirements for the special SSI eligibility status.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Requirements for the special SSI eligibility status. 416.265 Section 416.265 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A Disabling Impairment § 416.265 Requirement...

27 CFR 26.265 - Determination of tax on articles.

Code of Federal Regulations, 2011 CFR

2011-04-01

... articles. 26.265 Section 26.265 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS LIQUORS AND ARTICLES FROM PUERTO RICO AND THE VIRGIN ISLANDS Procedure at Port of Entry From the Virgin Islands § 26.265 Determination of tax on articles. Where articles...

Preliminary results on effect of H2S on P265GH commercial material for natural gases and petroleum transportation

NASA Astrophysics Data System (ADS)

Zaharia, Marius Gabriel; Stanciu, Sergiu; Cimpoesu, Ramona; Ionita, Iulian; Cimpoesu, Nicanor

2018-04-01

A commercial Fe-C material (P265GH) used for natural gas delivery and transportation systems was analyzed in H2S atmosphere in order to establish the corrosion resistance. In most of the industrial processes for gas purification the corrosion rate is speed up by the presence of sulphur (S) especially as ions (HS-, SO32-) or different species like H2S. The H2S (hydrogen sulphide) is, beside a very toxic compound, a very active element in the acceleration of metallic materials deterioration. For experiments we used a three electrodes cell with Na2SO4 + Na2S solution at pH 3 for two different temperatures, room temperature ∼ 25 °C (sample 1) and at 60 (sample 2) ±1 °C in order to realize EIS (electrochemical impedance spectroscopy) and potentiodynamic polarization. After electro-chemical tests and corrosion resistance characterisation the material surface was analyzed using scanning electron microscopy (SEM), X-ray diffraction (XRD) and energy dispersive spectroscopy (EDS).

Mesocarbon microbead based graphite for spherical fuel element to inhibit the infiltration of liquid fluoride salt in molten salt reactor

NASA Astrophysics Data System (ADS)

Zhong, Yajuan; Zhang, Junpeng; Lin, Jun; Xu, Liujun; Zhang, Feng; Xu, Hongxia; Chen, Yu; Jiang, Haitao; Li, Ziwei; Zhu, Zhiyong; Guo, Quangui

2017-07-01

Mesocarbon microbeads (MCMB) and quasi-isostatic pressing method were used to prepare MCMB based graphite (MG) for spherical fuel element to inhibit the infiltration of liquid fluoride salt in molten salt reactor (MSR). Characteristics of mercury infiltration and molten salt infiltration in MG were investigated and compared with A3-3 (graphite for spherical fuel element in high temperature gas cooled reactor) to identify the infiltration behaviors. The results indicated that MG had a low porosity about 14%, and an average pore diameter of 96 nm. Fluoride salt occupation of A3-3 (average pore diameter was 760 nm) was 10 wt% under 6.5 atm, whereas salt gain did not infiltrate in MG even up to 6.5 atm. It demonstrated that MG could inhibit the infiltration of liquid fluoride salt effectively. Coefficient of thermal expansion (CTE) of MG lies in 6.01 × 10-6 K-1 (α∥) and 6.15 × 10-6 K-1 (α⊥) at the temperature range of 25-700 °C. The anisotropy factor of MG calculated by CTE maintained below 1.02, which could meet the requirement of the spherical fuel element (below 1.30). The constant isotropic property of MG is beneficial for the integrity and safety of the graphite used in the spherical fuel element for a MSR.

HLA class I-restricted MYD88 L265P-derived peptides as specific targets for lymphoma immunotherapy

PubMed Central

Nelde, Annika; Walz, Juliane Sarah; Kowalewski, Daniel Johannes; Schuster, Heiko; Wolz, Olaf-Oliver; Peper, Janet Kerstin; Cardona Gloria, Yamel; Langerak, Anton W.; Muggen, Alice F.; Claus, Rainer; Bonzheim, Irina; Fend, Falko; Salih, Helmut Rainer; Kanz, Lothar; Rammensee, Hans-Georg; Stevanović, Stefan; Weber, Alexander N. R.

2017-01-01

ABSTRACT Genome sequencing has uncovered an array of recurring somatic mutations in different non-Hodgkin lymphoma (NHL) subtypes. If affecting protein-coding regions, such mutations may yield mutation-derived peptides that may be presented by HLA class I proteins and recognized by cytotoxic T cells. A recurring somatic and oncogenic driver mutation of the Toll-like receptor adaptor protein MYD88, Leu265Pro (L265P) was identified in up to 90% of different NHL subtype patients. We therefore screened the potential of MYD88L265P-derived peptides to elicit cytotoxic T cell responses as tumor-specific neoantigens. Based on in silico predictions, we identified potential MYD88L265P-containing HLA ligands for several HLA class I restrictions. A set of HLA class I MYD88L265P-derived ligands elicited specific cytotoxic T cell responses for HLA-B*07 and -B*15. These data highlight the potential of MYD88L265P mutation-specific peptide-based immunotherapy as a novel personalized treatment approach for patients with MYD88L265P+ NHLs that may complement pharmacological approaches targeting oncogenic MyD88 L265P signaling. PMID:28405493

Numerical Simulation of Wear in a C/C Composite Multidisk Clutch (Preprint)

DTIC Science & Technology

2009-04-01

subroutine FRIC, in the commercial finite element software ( ABAQUS , 6.5-1, Pawtucket, RI) [25], to calculate the local wear depth increment (decrease in...temperature continuity and the heat balance conditions must be satisfied. The subroutine FRIC in ABAQUS code [25] is called only when the contact point is...0.33, thermal expansion coefficients αr = 0.31x10-6/K, αz = 0.29x10-6/K, friction coefficient µ = 0.20, heat convection coefficient h = 100 W/m2K

45 CFR 265.5 - May States use sampling?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false May States use sampling? 265.5 Section 265.5... REQUIREMENTS § 265.5 May States use sampling? (a) Each State may report the disaggregated data in the TANF Data... the use of a scientifically acceptable sampling method that we have approved. States may use sampling...

45 CFR 265.5 - May States use sampling?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false May States use sampling? 265.5 Section 265.5... REQUIREMENTS § 265.5 May States use sampling? (a) Each State may report the disaggregated data in the TANF Data... the use of a scientifically acceptable sampling method that we have approved. States may use sampling...

41 CFR 301-10.265 - Will my travel on Government aircraft be reported?

Code of Federal Regulations, 2010 CFR

2010-07-01

... are a senior Federal official or a non-Federal traveler, any use you make of Government aircraft, i.e... Government aircraft be reported? 301-10.265 Section 301-10.265 Public Contracts and Property Management...-TRANSPORTATION EXPENSES Government Vehicle Travel on Government Aircraft § 301-10.265 Will my travel on...

41 CFR 301-10.265 - Will my travel on Government aircraft be reported?

Code of Federal Regulations, 2011 CFR

2011-07-01

... are a senior Federal official or a non-Federal traveler, any use you make of Government aircraft, i.e... Government aircraft be reported? 301-10.265 Section 301-10.265 Public Contracts and Property Management...-TRANSPORTATION EXPENSES Government Vehicle Travel on Government Aircraft § 301-10.265 Will my travel on...

40 CFR 265.276 - Food chain crops.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Food chain crops. 265.276 Section 265... FACILITIES Land Treatment § 265.276 Food chain crops. (a) An owner or operator of a hazardous waste land treatment facility on which food chain crops are being grown, or have been grown and will be grown in the...

40 CFR 265.276 - Food chain crops.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Food chain crops. 265.276 Section 265... FACILITIES Land Treatment § 265.276 Food chain crops. (a) An owner or operator of a hazardous waste land treatment facility on which food chain crops are being grown, or have been grown and will be grown in the...

40 CFR 265.276 - Food chain crops.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Food chain crops. 265.276 Section 265... FACILITIES Land Treatment § 265.276 Food chain crops. (a) An owner or operator of a hazardous waste land treatment facility on which food chain crops are being grown, or have been grown and will be grown in the...

40 CFR 265.276 - Food chain crops.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Food chain crops. 265.276 Section 265... FACILITIES Land Treatment § 265.276 Food chain crops. (a) An owner or operator of a hazardous waste land treatment facility on which food chain crops are being grown, or have been grown and will be grown in the...

40 CFR 265.276 - Food chain crops.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Food chain crops. 265.276 Section 265... FACILITIES Land Treatment § 265.276 Food chain crops. (a) An owner or operator of a hazardous waste land treatment facility on which food chain crops are being grown, or have been grown and will be grown in the...

26 CFR 1.265-2 - Interest relating to tax exempt income.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Interest relating to tax exempt income. 1.265-2 Section 1.265-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Items Not Deductible § 1.265-2 Interest relating to tax exempt income. (a...

46 CFR 148.265 - Fish meal or fish scrap.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 5 2014-10-01 2014-10-01 false Fish meal or fish scrap. 148.265 Section 148.265... MATERIALS THAT REQUIRE SPECIAL HANDLING Special Requirements for Certain Materials § 148.265 Fish meal or fish scrap. (a) This part does not apply to fish meal or fish scrap that contains less than 5 percent...

46 CFR 148.265 - Fish meal or fish scrap.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 5 2013-10-01 2013-10-01 false Fish meal or fish scrap. 148.265 Section 148.265... MATERIALS THAT REQUIRE SPECIAL HANDLING Special Requirements for Certain Materials § 148.265 Fish meal or fish scrap. (a) This part does not apply to fish meal or fish scrap that contains less than 5 percent...

46 CFR 148.265 - Fish meal or fish scrap.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 5 2012-10-01 2012-10-01 false Fish meal or fish scrap. 148.265 Section 148.265... MATERIALS THAT REQUIRE SPECIAL HANDLING Special Requirements for Certain Materials § 148.265 Fish meal or fish scrap. (a) This part does not apply to fish meal or fish scrap that contains less than 5 percent...

40 CFR 265.94 - Recordkeeping and reporting.

Code of Federal Regulations, 2011 CFR

2011-07-01

... required in § 265.92(e), and the evaluations required in § 265.93(b) throughout the active life of the... found in the upgradient wells, in accordance with § 265.93(c)(1). During the active life of the facility, this information must be submitted no later than March 1 following each calendar year. (iii) No later...

45 CFR 265.10 - When is the annual report due?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true When is the annual report due? 265.10 Section 265.10 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES DATA COLLECTION AND REPORTING REQUIREMENTS § 265.10 When is...

45 CFR 265.4 - When are quarterly reports due?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true When are quarterly reports due? 265.4 Section 265.4 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES DATA COLLECTION AND REPORTING REQUIREMENTS § 265.4 When are...

21 CFR 1271.265 - Receipt, predistribution shipment, and distribution of an HCT/P.

Code of Federal Regulations, 2011 CFR

2011-04-01

... and constructed to protect the HCT/P from contamination. For each type of HCT/P, you must establish... distribution of an HCT/P. 1271.265 Section 1271.265 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... Practice § 1271.265 Receipt, predistribution shipment, and distribution of an HCT/P. (a) Receipt. You must...

25 CFR 26.5 - Who may be eligible for Job Placement and Training?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 1 2013-04-01 2013-04-01 false Who may be eligible for Job Placement and Training? 26.5 Section 26.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES JOB PLACEMENT AND TRAINING PROGRAM General Applicability § 26.5 Who may be eligible for Job Placement and Training? You may...

25 CFR 26.5 - Who may be eligible for Job Placement and Training?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 1 2012-04-01 2011-04-01 true Who may be eligible for Job Placement and Training? 26.5 Section 26.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES JOB PLACEMENT AND TRAINING PROGRAM General Applicability § 26.5 Who may be eligible for Job Placement and Training? You may...

25 CFR 26.5 - Who may be eligible for Job Placement and Training?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false Who may be eligible for Job Placement and Training? 26.5 Section 26.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES JOB PLACEMENT AND TRAINING PROGRAM General Applicability § 26.5 Who may be eligible for Job Placement and Training? You may...

25 CFR 26.5 - Who may be eligible for Job Placement and Training?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 1 2014-04-01 2014-04-01 false Who may be eligible for Job Placement and Training? 26.5 Section 26.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES JOB PLACEMENT AND TRAINING PROGRAM General Applicability § 26.5 Who may be eligible for Job Placement and Training? You may...

25 CFR 26.5 - Who may be eligible for Job Placement and Training?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Who may be eligible for Job Placement and Training? 26.5 Section 26.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES JOB PLACEMENT AND TRAINING PROGRAM General Applicability § 26.5 Who may be eligible for Job Placement and Training? You may...

12 CFR 265.8 - Functions delegated to the Staff Director of the Division of International Finance.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Functions delegated to the Staff Director of the Division of International Finance. 265.8 Section 265.8 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM RULES REGARDING DELEGATION OF AUTHORITY § 265.8 Functions delegated to the Staff Director...

Biological and Clinical Relevance of Associated Genomic Alterations in MYD88 L265P and non-L265P-Mutated Diffuse Large B-Cell Lymphoma: Analysis of 361 Cases.

PubMed

Dubois, Sydney; Viailly, Pierre-Julien; Bohers, Elodie; Bertrand, Philippe; Ruminy, Philippe; Marchand, Vinciane; Maingonnat, Catherine; Mareschal, Sylvain; Picquenot, Jean-Michel; Penther, Dominique; Jais, Jean-Philippe; Tesson, Bruno; Peyrouze, Pauline; Figeac, Martin; Desmots, Fabienne; Fest, Thierry; Haioun, Corinne; Lamy, Thierry; Copie-Bergman, Christiane; Fabiani, Bettina; Delarue, Richard; Peyrade, Frédéric; André, Marc; Ketterer, Nicolas; Leroy, Karen; Salles, Gilles; Molina, Thierry J; Tilly, Hervé; Jardin, Fabrice

2017-05-01

Purpose: MYD88 mutations, notably the recurrent gain-of-function L265P variant, are a distinguishing feature of activated B-cell like (ABC) diffuse large B-cell lymphoma (DLBCL), leading to constitutive NFκB pathway activation. The aim of this study was to examine the distinct genomic profiles of MYD88 -mutant DLBCL, notably according to the presence of the L265P or other non-L265P MYD88 variants. Experimental Design: A cohort of 361 DLBCL cases (94 MYD88 mutant and 267 MYD88 wild-type) was submitted to next-generation sequencing (NGS) focusing on 34 genes to analyze associated mutations and copy number variations, as well as gene expression profiling, and clinical and prognostic analyses. Results: Importantly, we highlighted different genomic profiles for MYD88 L265P and MYD88 non-L265P-mutant DLBCL, shedding light on their divergent backgrounds. Clustering analysis also segregated subgroups according to associated genetic alterations among patients with the same MYD88 mutation. We showed that associated CD79B and MYD88 L265P mutations act synergistically to increase NFκB pathway activation, although the majority of MYD88 L265P-mutant cases harbors downstream NFκB alterations, which can predict BTK inhibitor resistance. Finally, although the MYD88 L265P variant was not an independent prognostic factor in ABC DLBCL, associated CD79B mutations significantly improved the survival of MYD88 L265P-mutant ABC DLBCL in our cohort. Conclusions: This study highlights the relative heterogeneity of MYD88 -mutant DLBCL, adding to the field's knowledge of the theranostic importance of MYD88 mutations, but also of associated alterations, emphasizing the usefulness of genomic profiling to best stratify patients for targeted therapy. Clin Cancer Res; 23(9); 2232-44. ©2016 AACR . ©2016 American Association for Cancer Research.

Seasonal and interannual variability in along-slope oceanic properties off the US West Coast: Inferences from a high-resolution regional model

NASA Astrophysics Data System (ADS)

Kurapov, A. L.; Pelland, N. A.; Rudnick, D. L.

2017-07-01

A 6 year, 2009-2014 simulation using a 2 km horizontal resolution ocean circulation model of the Northeast Pacific coast is analyzed with focus on seasonal and interannual variability in along-slope subsurface oceanic properties. Specifically, the fields are sampled on the isopycnal surface σ=26.5 kg m-3 that is found between depths of 150 and 300 m below the ocean surface over the continental slope. The fields analyzed include the depth z26.5, temperature T26.5, along-slope current v26.5, and the average potential vorticity PV between σ = 26.5 and 26.25 kg m-3. Each field is averaged in the cross-shore direction over the continental slope and presented as a function of the alongshore coordinate and time. The seasonal cycle in z26.5 shows a coherent upwelling-downwelling pattern from Mexico to Canada propagating to the north with a speed of 0.5 m s-1. The anomalously deep (-20 m) z26.5 displacement in spring-summer 2014 is forced by the southern boundary condition at 24°N as a manifestation of an emerging strong El Niño. The seasonal cycle in T26.5 is most pronounced between 36°N and 53°N indicating that subarctic waters are replaced by warmer Californian waters in summer with the speed close 0.15 m s-1, which is consistent with earlier estimates of the undercurrent speed and also present v26.5 analyses. The seasonal patterns and anomalies in z26.5 and T26.5 find confirmation in available long-term glider and shipborne observations. The PV seasonality over the slope is qualitatively different to the south and north of the southern edge of Heceta Bank (43.9°N).

Frequently asked questions of individuals with spinal cord injuries: results of a web-based consultation service in Iran.

PubMed

Rezaei, Mojtaba; Omidbeigi, Mahmoud; Hanaei, Sara; Saeedi, Negin; Naghdi, Khatereh; Vaccaro, Alexander R; Rahimi-Movaghar, Vafa

2018-01-01

Descriptive study of the results of a web-based consultation service for individuals with spinal cord injury (SCI). To review frequently asked questions (FAQ) among individuals with SCI and determine the most important topics. Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran. A cross-sectional study reviewing questions from patients with SCI that were collected from the Health and Safety Consultant Center (HSCC) between January and December 2015. The HSCC is a web-based medical consultation service that provides patients with information and counseling pertaining to SCI. A total of 113 questions were collected from 99 individuals. The mean age was 32.02 ± 13.28 years with a range of 3-70 years. Men accounted for 81.7% of the questions, while women accounted for 18.3%. The most common site of SCI was thoracic (40.6%), followed by lumbar (31.3%), and cervical (28.1%). Recovery potential (38.1%), sexual and reproductive issues (26.5%), urinary (10.6%), and motor (10.6%) problems were among the most commonly reviewed topics. FAQ provide insight on areas of concerns for individuals with SCI and help guide providers to determine high-yield topics. Discerning the specific areas of need or concern for patients is instrumental in developing pertinent educational materials and programs, in addition to efficiently counseling patients and caregivers on the aftercare of SCI.

Evaluation of electrocardiographic parameters in patients with diabetes insipidus.

PubMed

Deniz, Ferhat; Kepez, Alper; Ay, Seyit Ahmet; Ergogan, Okan; Baskoy, Kamil; Guncıkan, Mustafa Nuri; Dogan, Zekeriya; Yonem, Arif

2015-11-01

There is limited data regarding the effect of altered serum osmolality on cardiac electrical activity. The aim of the present study is to evaluate the electrocardiographic (ECG) effects of diabetes insipidus (DI) and any related hyperosmolality in a population of young patients with DI and without any known cardiovascular disease or risk factors. Twelve-lead ECG's of 44 consecutive untreated young male patients (age: 21.8 ± 2.9 years) who had been referred to endocrinology clinic and diagnosed as DI based on water deprivation test were retrospectively evaluated. A total of 30 age-matched (21.9 ± 2.4 years) healthy males were selected as control group and ECG's of these controls were obtained for comparison with ECG's of DI patients. All ECG parameters were measured and compared. Duration of QRS complex was significantly shorter in patients with DI compared with controls (85.2 ± 12.0 vs. 94.0 ± 10.6 ms, p: 0.001). P wave dispersion (PWD) of patients with DI was significantly higher compared with controls (31.9 ± 9.9 vs. 26.5 ± 10.6 ms, p: 0.03) and it was significantly correlated with serum osmolality and serum sodium level (r = - 0.36, p: 0.02 and r: - 0.35, p: 0.02, respectively). DI patients without any cardiovascular disease or risk factors displayed significantly shorter QRS duration and increased p wave dispersion compared with controls.

Spatio-temporal variation of water flow and sediment discharge in the Mahanadi River, India

NASA Astrophysics Data System (ADS)

Bastia, Fakira; Equeenuddin, Sk. Md.

2016-09-01

The transport of sediments by rivers to the oceans represents an important link between the terrestrial and marine ecosystem. Therefore, this work aims to study spatio-temporal variation of the sediment discharge and erosion rate in the Mahanadi river, one of the biggest rivers in India, over past three decades vis-à-vis their controlling factors. To understand the sediment load variation, the trend analysis in the time series data of rainfall, water and sediment discharge of the Mahanadi river were also attempted. The non-parametric Mann-Kendall and Sen's methods were used to determine whether there was a positive or negative trend in the time series data with their statistical significance. The occurrence of abrupt changes was detected using Pettitt test. The trend test result represents that sediment load delivered from the Mahanadi river to the global ocean has decreased sharply at the rate of 0.515 × 106 tons/year between 1980 and 2010. Water discharge and rainfall in the basin showed no significant decreasing trend except at only one tributary. The decline in sediment discharge from the basin to the Bay of Bengal is mainly due to the increase in the number of dams, which has recorded the increase from 70 to 253 during the period of 1980 to 2010. Over the past 30 years the Mahanadi river has discharged about 49.0 ± 20.5 km3 of water and 17.4 ± 12.7 × 106 tons of sediment annually to the Bay of Bengal whereas the mean erosional rate is 265 ± 125 tons/km2/year over the period of 30 years in the basin. Based on the current data (2000-2001 to 2009-2010), sediment flux and water discharge to the ocean are 12 ± 5 × 106 tons/year and 49 ± 16 km3/year respectively; and ranking Mahanadi river second in terms of water discharge and sediment flux to the ocean among the peninsular rivers in India.

The carrier gas pressure effect in a laminar flow diffusion chamber, homogeneous nucleation of n-butanol in helium.

PubMed

Hyvärinen, Antti-Pekka; Brus, David; Zdímal, Vladimír; Smolík, Jiri; Kulmala, Markku; Viisanen, Yrjö; Lihavainen, Heikki

2006-06-14

Homogeneous nucleation rate isotherms of n-butanol+helium were measured in a laminar flow diffusion chamber at total pressures ranging from 50 to 210 kPa to investigate the effect of carrier gas pressure on nucleation. Nucleation temperatures ranged from 265 to 280 K and the measured nucleation rates were between 10(2) and 10(6) cm(-3) s(-1). The measured nucleation rates decreased as a function of increasing pressure. The pressure effect was strongest at pressures below 100 kPa. This negative carrier gas effect was also temperature dependent. At nucleation temperature of 280 K and at the same saturation ratio, the maximum deviation between nucleation rates measured at 50 and 210 kPa was about three orders of magnitude. At nucleation temperature of 265 K, the effect was negligible. Qualitatively the results resemble those measured in a thermal diffusion cloud chamber. Also the slopes of the isothermal nucleation rates as a function of saturation ratio were different as a function of total pressure, 50 kPa isotherms yielded the steepest slopes, and 210 kPa isotherms the shallowest slopes. Several sources of inaccuracies were considered in the interpretation of the results: uncertainties in the transport properties, nonideal behavior of the vapor-carrier gas mixture, and shortcomings of the used mathematical model. Operation characteristics of the laminar flow diffusion chamber at both under-and over-pressure were determined to verify a correct and stable operation of the device. We conclude that a negative carrier gas pressure effect is seen in the laminar flow diffusion chamber and it cannot be totally explained with the aforementioned reasons.

A mutation in MYD88 (L265P) supports the survival of lymphoplasmacytic cells by activation of Bruton tyrosine kinase in Waldenström macroglobulinemia.

PubMed

Yang, Guang; Zhou, Yangsheng; Liu, Xia; Xu, Lian; Cao, Yang; Manning, Robert J; Patterson, Christopher J; Buhrlage, Sara J; Gray, Nathanael; Tai, Yu-Tzu; Anderson, Kenneth C; Hunter, Zachary R; Treon, Steven P

2013-08-15

Myeloid differentiation factor 88 (MYD88) L265P somatic mutation is highly prevalent in Waldenström macroglobulinemia (WM) and supports malignant growth through nuclear factor κB (NF-κB). The signaling cascade(s) by which MYD88 L265P promotes NF-κB activation in WM remain unclear. By lentiviral knockdown or use of a MYD88 inhibitor, decreased phosphorylation of the NF-κB gatekeeper IκBα and survival occurred in MYD88 L265P-expressing WM cells. Conversely, WM cells engineered to overexpress MYD88 L265P showed enhanced survival. Coimmunoprecipitation studies identified Bruton tyrosine kinase (BTK) complexed to MYD88 in L265P-expressing WM cells, with preferential binding of MYD88 to phosphorylated BTK (pBTK). Increased pBTK was also observed in WM cells transduced to overexpress L265P vs wild-type MYD88. Importantly, MYD88 binding to BTK was abrogated following treatment of MYD88 L265P-expressing cells with a BTK kinase inhibitor. Inhibition of BTK or interleukin-1 receptor-associated kinase 1 and 4 (IRAK-1 and -4) kinase activity induced apoptosis of WM cells, and their combination resulted in more robust inhibition of NF-κB signaling and synergistic WM cell killing. The results establish BTK as a downstream target of MYD88 L265P signaling, and provide a framework for the study of BTK inhibitors alone, and in combination with IRAK inhibitors for the treatment of WM.

An analysis of human exposure to trace elements from deliberate soil ingestion and associated health risks.

PubMed

Ngole-Jeme, Veronica M; Ekosse, Georges-Ive E; Songca, Sandile P

2018-01-01

Fifty-seven samples of soils commonly ingested in South Africa, Swaziland, Democratic Republic of Congo (DRC), and Togo were analyzed for the concentrations of arsenic (As), cadmium (Cd), cobalt (Co), chromium (Cr), copper (Cu), lead (Pb), manganese (Mn), nickel (Ni), and zinc (Zn) and their bioaccessibility in the human gastrointestinal tract. Bioaccessibility values were used to calculate daily intake, and hazard quotient of each trace element, and chronic hazard index (CHI) of each sample. Carcinogenic risk associated with As and Ni exposure were also calculated. Mean pseudo-total concentrations of trace elements in all samples were 7.2, 83.3, 77.1, 15.4, 28.6, 24.9, 56.1, 2.8, and 26.5 mg/kg for As, Cr, Mn, Co, Ni, Cu, Zn, Cd, and Pb, respectively. Percent bioaccessibility of Pb (13-49%) and Zn (38-56%) were highest among trace elements studied. Average daily intake values were lower than their respective reference doses for ell elements except for Pb in selected samples. Samples from DRC presented the highest health risks associated with trace element exposure with most of the samples having CHI values between 0.5 and 1.0. Some samples had higher than unacceptable values of carcinogenic risk associated with As and Ni exposure. Results indicate low trace element exposure risk from ingesting most of the soil samples.

15 CFR 265.18 - Prohibited servicing of vehicles.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Prohibited servicing of vehicles. 265... § 265.18 Prohibited servicing of vehicles. No person shall make nonemergency repairs on privately owned vehicles on the site. ...

15 CFR 265.18 - Prohibited servicing of vehicles.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Prohibited servicing of vehicles. 265... § 265.18 Prohibited servicing of vehicles. No person shall make nonemergency repairs on privately owned vehicles on the site. ...

7 CFR 4279.265 - Guarantee application evaluation.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 15 2014-01-01 2014-01-01 false Guarantee application evaluation. 4279.265 Section 4279.265 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Biorefinery...

7 CFR 4279.265 - Guarantee application evaluation.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 15 2012-01-01 2012-01-01 false Guarantee application evaluation. 4279.265 Section 4279.265 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Biorefinery...

7 CFR 4279.265 - Guarantee application evaluation.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 15 2013-01-01 2013-01-01 false Guarantee application evaluation. 4279.265 Section 4279.265 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Biorefinery...

Video Compression Study: h.265 vs h.264

NASA Technical Reports Server (NTRS)

Pryor, Jonathan

2016-01-01

H.265 video compression (also known as High Efficiency Video Encoding (HEVC)) promises to provide double the video quality at half the bandwidth, or the same quality at half the bandwidth of h.264 video compression [1]. This study uses a Tektronix PQA500 to determine the video quality gains by using h.265 encoding. This study also compares two video encoders to see how different implementations of h.264 and h.265 impact video quality at various bandwidths.

Design and activity of novel lactoferrampin analogues against O157:H7 enterohemorrhagic Escherichia coli.

PubMed

Cruz, Jenniffer; Ortiz, Claudia; Guzmán, Fanny; Cárdenas, Constanza; Fernandez-Lafuente, Roberto; Torres, Rodrigo

2014-04-01

Lactoferrampin 265-284 (LFampin 265-284) is a peptide consisting of residues 265-284 of N1-domain of bovine Lactoferrin (LF). This peptide has several cationic groups in the C-terminal lobe, exhibiting an antibacterial activity against a wide range of microorganisms. However, LFampin 265-284 exhibits low antimicrobial activity against the O157:H7 enterohaemorrhagic Escherichia coli (EHEC O157:H7) when compared with Lactoferrin chimera and Lactoferricin. Here, we have designed three analogues of LFampin 265-284 based on the distribution of cationic groups, hydrophobicity, size, and sequence. Analogues were synthesized by solid phase chemistry using Fmoc methodology obtaining peptides with 95% purity. All peptides maintain the ability to adopt helical conformations (checked by circular dichroism spectra and molecular simulations). Some of these analogues exhibited a significant increase in antimicrobial activity by counting colony forming units against EHEC O157:H7 compared to native LFampin 265-284, with MIC of 10 and 40 µM for 264G-D265K and 264G-D265K/S272R, respectively. The incorporation of a GKLI sequence in the N-terminal lobe increased dramatically its antibacterial activity, an effect which has been attributed to the addition of cationic groups in the N-terminal side that may stabilize the helical conformation of the new designed peptides. Copyright © 2013 Wiley Periodicals, Inc.

41 CFR 102-118.265 - What is a prepayment audit?

Code of Federal Regulations, 2010 CFR

2010-07-01

... audit? 102-118.265 Section 102-118.265 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION TRANSPORTATION 118-TRANSPORTATION PAYMENT AND AUDIT Prepayment Audits of Transportation Services Agency Requirements for Prepayment Audits...

40 CFR 265.118 - Post-closure plan; amendment of plan.

Code of Federal Regulations, 2011 CFR

2011-07-01

... the wastes, application of advanced technology, or alternative disposal, treatment, or re-use.... 265.118 Section 265.118 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT...

40 CFR 265.1200 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-07-01

... FACILITIES Hazardous Waste Munitions and Explosives Storage § 265.1200 Applicability. The requirements of this subpart apply to owners or operators who store munitions and explosive hazardous wastes, except as § 265.1 provides otherwise. (NOTE: Depending on explosive hazards, hazardous waste munitions and...

40 CFR 265.1200 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-07-01

... FACILITIES Hazardous Waste Munitions and Explosives Storage § 265.1200 Applicability. The requirements of this subpart apply to owners or operators who store munitions and explosive hazardous wastes, except as § 265.1 provides otherwise. (NOTE: Depending on explosive hazards, hazardous waste munitions and...

40 CFR 265.1200 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... FACILITIES Hazardous Waste Munitions and Explosives Storage § 265.1200 Applicability. The requirements of this subpart apply to owners or operators who store munitions and explosive hazardous wastes, except as § 265.1 provides otherwise. (NOTE: Depending on explosive hazards, hazardous waste munitions and...

40 CFR 265.1200 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... FACILITIES Hazardous Waste Munitions and Explosives Storage § 265.1200 Applicability. The requirements of this subpart apply to owners or operators who store munitions and explosive hazardous wastes, except as § 265.1 provides otherwise. (NOTE: Depending on explosive hazards, hazardous waste munitions and...

40 CFR 265.1200 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-07-01

... FACILITIES Hazardous Waste Munitions and Explosives Storage § 265.1200 Applicability. The requirements of this subpart apply to owners or operators who store munitions and explosive hazardous wastes, except as § 265.1 provides otherwise. (NOTE: Depending on explosive hazards, hazardous waste munitions and...

External Tank (ET) Foam Thermal/Structural Analysis Project

NASA Technical Reports Server (NTRS)

Moore, David F.; Ungar, Eugene K.; Chang, Li C.; Malroy, Eric T.; Stephan, Ryan A.

2008-01-01

An independent study was performed to assess the pre-launch thermally induced stresses in the Space Shuttle External Tank Bipod closeout and Ice/Frost ramps (IFRs). Finite element models with various levels of detail were built that included the three types of foam (BX-265, NCFI 24-124, and PDL 1034) and the underlying structure and bracketry. Temperature profiles generated by the thermal analyses were input to the structural models to calculate the stress levels. An area of high stress in the Bipod closeout was found along the aluminum tank wall near the phenolic insulator and along the phenolic insulator itself. This area of high stress might be prone to cracking and possible delamination. There is a small region of slightly increased stress in the NCFI 24-124 foam near its joint with the Bipod closeout BX-265 foam. The calculated stresses in the NCFI 24-124 acreage foam are highest at the NCFI 24-124/PDL 1034/tank wall interface under the LO2 and LH2 IFRs. The highest calculated stresses in the LH2 NCFI 24-124 foam are higher than in similar locations in the LO2 IFR. This finding is consistent with the dissection results of IFRs on ET-120.

40 CFR 265.441 - Assessment of existing drip pad integrity.

Code of Federal Regulations, 2010 CFR

2010-07-01

... detection systems of § 265.443(b). No later than the effective date of this rule, the owner or operator must... standards for liners and leak detection systems, specified in § 265.443(b). (b) The owner or operator must...

15 CFR 265.16 - Parking.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Parking. 265.16 Section 265.16 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE REGULATIONS GOVERNING TRAFFIC AND CONDUCT REGULATIONS...

15 CFR 265.16 - Parking.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Parking. 265.16 Section 265.16 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE REGULATIONS GOVERNING TRAFFIC AND CONDUCT REGULATIONS...

15 CFR 265.16 - Parking.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Parking. 265.16 Section 265.16 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE REGULATIONS GOVERNING TRAFFIC AND CONDUCT REGULATIONS...

40 CFR 265.77 - Additional reports.

Code of Federal Regulations, 2011 CFR

2011-07-01

....77 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL... submitting the biennial report and unmanifested waste reports described in §§ 265.75 and 265.76, the owner or...

40 CFR 265.272 - General operating requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false General operating requirements. 265.272 Section 265.272 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... nonhazardous by degradation, transformation, or immobilization processes occurring in or on the soil. (b) The...

40 CFR 265.31 - Maintenance and operation of facility.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., soil, or surface water which could threaten human health or the -environment. ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Maintenance and operation of facility. 265.31 Section 265.31 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID...

40 CFR 265.1201 - Design and operating standards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Design and operating standards. 265.1201 Section 265.1201 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID...) Provide monitoring and inspection procedures that assure the controls and containment systems are working...

40 CFR 265.76 - Unmanifested waste report.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Unmanifested waste report. 265.76 Section 265.76 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND...

40 CFR 265.13 - General waste analysis.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false General waste analysis. 265.13 Section 265.13 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL...

40 CFR 265.76 - Unmanifested waste report.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Unmanifested waste report. 265.76 Section 265.76 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND...

40 CFR 265.76 - Unmanifested waste report.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Unmanifested waste report. 265.76 Section 265.76 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND...

40 CFR 265.13 - General waste analysis.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false General waste analysis. 265.13 Section 265.13 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL...

40 CFR 265.76 - Unmanifested waste report.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Unmanifested waste report. 265.76 Section 265.76 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND...

40 CFR 265.13 - General waste analysis.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false General waste analysis. 265.13 Section 265.13 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL...

40 CFR 265.76 - Unmanifested waste report.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Unmanifested waste report. 265.76 Section 265.76 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND...

40 CFR 265.13 - General waste analysis.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false General waste analysis. 265.13 Section 265.13 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL...

40 CFR 265.250 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Piles § 265.250 Applicability. The regulations in this subpart apply to owners and operators of facilities that treat or store hazardous waste in piles, except as § 265.1 provides otherwise. Alternatively, a pile of hazardous waste may be managed as a landfill under subpart N. ...

40 CFR 265.198 - Special requirements for ignitable or reactive wastes.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) The resulting waste, mixture, or dissolved material no longer meets the definition of ignitable or... reactive wastes. 265.198 Section 265.198 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE...

40 CFR 265.140 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... this subpart applying to a regulated unit with alternative requirements for financial assurance set out... STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Financial... Administrator: (1) Prescribes alternative requirements for the regulated unit under § 265.90(f) and/or 265.110(d...

40 CFR 265.174 - Inspections.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Management of Containers § 265.174 Inspections. At least weekly, the owner or operator must inspect areas where containers are stored, except for Performance Track member facilities, that must conduct..., the Performance Track member facility must follow the procedures described in § 265.15(b)(5) of this...

40 CFR 265.174 - Inspections.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Management of Containers § 265.174 Inspections. At least weekly, the owner or operator must inspect areas where containers are stored, except for Performance Track member facilities, that must conduct..., the Performance Track member facility must follow the procedures described in § 265.15(b)(5) of this...

40 CFR 265.174 - Inspections.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Management of Containers § 265.174 Inspections. At least weekly, the owner or operator must inspect areas where containers are stored, except for Performance Track member facilities, that must conduct..., the Performance Track member facility must follow the procedures described in § 265.15(b)(5) of this...

40 CFR 265.174 - Inspections.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Management of Containers § 265.174 Inspections. At least weekly, the owner or operator must inspect areas where containers are stored, except for Performance Track member facilities, that must conduct..., the Performance Track member facility must follow the procedures described in § 265.15(b)(5) of this...

40 CFR 265.174 - Inspections.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Management of Containers § 265.174 Inspections. At least weekly, the owner or operator must inspect areas where containers are stored, except for Performance Track member facilities, that must conduct..., the Performance Track member facility must follow the procedures described in § 265.15(b)(5) of this...

40 CFR 265.254 - Design and operating requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

....254 Section 265.254 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Waste Piles § 265.254 Design and operating requirements. The owner or operator of each...

40 CFR 1065.265 - Nonmethane cutter.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 33 2014-07-01 2014-07-01 false Nonmethane cutter. 1065.265 Section 1065.265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS... sample with purified air or oxygen (O2) upstream of the nonmethane cutter to optimize its performance...

40 CFR 1065.265 - Nonmethane cutter.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 34 2012-07-01 2012-07-01 false Nonmethane cutter. 1065.265 Section 1065.265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS... sample with purified air or oxygen (O2) upstream of the nonmethane cutter to optimize its performance...

40 CFR 1065.265 - Nonmethane cutter.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 33 2011-07-01 2011-07-01 false Nonmethane cutter. 1065.265 Section 1065.265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS... with purified air or oxygen (O2) upstream of the nonmethane cutter to optimize its performance. You...

40 CFR 1065.265 - Nonmethane cutter.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Nonmethane cutter. 1065.265 Section 1065.265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS... with purified air or oxygen (O2) upstream of the nonmethane cutter to optimize its performance. You...

40 CFR 1065.265 - Nonmethane cutter.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 34 2013-07-01 2013-07-01 false Nonmethane cutter. 1065.265 Section 1065.265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS... sample with purified air or oxygen (O2) upstream of the nonmethane cutter to optimize its performance...

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

PubMed Central

Phillips, Margaret A.; Lotharius, Julie; Marsh, Kennan; White, John; Dayan, Anthony; White, Karen L.; Njoroge, Jacqueline W.; El Mazouni, Farah; Lao, Yanbin; Kokkonda, Sreekanth; Tomchick, Diana R.; Deng, Xiaoyi; Laird, Trevor; Bhatia, Sangeeta N.; March, Sandra; Ng, Caroline L.; Fidock, David A.; Wittlin, Sergio; Lafuente-Monasterio, Maria; Benito, Francisco Javier Gamo; Alonso, Laura Maria Sanz; Martinez, Maria Santos; Jimenez-Diaz, Maria Belen; Bazaga, Santiago Ferrer; Angulo-Barturen, Iñigo; Haselden, John N.; Louttit, James; Cui, Yi; Sridhar, Arun; Zeeman, Anna-Marie; Kocken, Clemens; Sauerwein, Robert; Dechering, Koen; Avery, Vicky M.; Duffy, Sandra; Delves, Michael; Sinden, Robert; Ruecker, Andrea; Wickham, Kristina S.; Rochford, Rosemary; Gahagen, Janet; Iyer, Lalitha; Riccio, Ed; Mirsalis, Jon; Bathhurst, Ian; Rueckle, Thomas; Ding, Xavier; Campo, Brice; Leroy, Didier; Rogers, M. John; Rathod, Pradipsinh K.; Burrows, Jeremy N.; Charman, Susan A.

2015-01-01

Malaria is one of the most significant causes of childhood mortality but disease control efforts are threatened by resistance of the Plasmodium parasite to current therapies. Continued progress in combating malaria requires development of new, easy to administer drug combinations with broad ranging activity against all manifestations of the disease. DSM265, a triazolopyrimidine-based inhibitor of the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase (DHODH), is the first DHODH inhibitor to reach clinical development for treatment of malaria. We describe studies profiling the biological activity, pharmacological and pharmacokinetic properties, and safety of DSM265, which supported its advancement to human trials. DSM265 is highly selective towards DHODH of the malaria parasite Plasmodium, efficacious against both blood and liver stages of P. falciparum, and active against drug-resistant parasite isolates. Favorable pharmacokinetic properties of DSM265 are predicted to provide therapeutic concentrations for more than 8 days after a single oral dose in the range of 200–400 mg. DSM265 was well tolerated in repeat dose and cardiovascular safety studies in mice and dogs, was not mutagenic, and was inactive against panels of human enzymes/receptors. The excellent safety profile, blood and liver-stage activity, and predicted long human half-life position DSM265 as a new potential drug combination partner for either single-dose treatment or once weekly chemoprevention. DSM265 has advantages over current treatment options that are dosed daily or are inactive on the parasite liver-stage PMID:26180101

40 CFR 265.309 - Surveying and recordkeeping.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Surveying and recordkeeping. 265.309... DISPOSAL FACILITIES Landfills § 265.309 Surveying and recordkeeping. The owner or operator of a landfill... location and dimensions, including depth, of each cell with respect to permanently surveyed benchmarks; and...

40 CFR 265.309 - Surveying and recordkeeping.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Surveying and recordkeeping. 265.309... DISPOSAL FACILITIES Landfills § 265.309 Surveying and recordkeeping. The owner or operator of a landfill... location and dimensions, including depth, of each cell with respect to permanently surveyed benchmarks; and...

40 CFR 265.309 - Surveying and recordkeeping.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Surveying and recordkeeping. 265.309... DISPOSAL FACILITIES Landfills § 265.309 Surveying and recordkeeping. The owner or operator of a landfill... location and dimensions, including depth, of each cell with respect to permanently surveyed benchmarks; and...

40 CFR 265.309 - Surveying and recordkeeping.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Surveying and recordkeeping. 265.309... DISPOSAL FACILITIES Landfills § 265.309 Surveying and recordkeeping. The owner or operator of a landfill... location and dimensions, including depth, of each cell with respect to permanently surveyed benchmarks; and...

5 CFR 532.265 - Special wage schedules for apprentices and shop trainees.

Code of Federal Regulations, 2012 CFR

2012-01-01

... and shop trainees. 532.265 Section 532.265 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT... schedules for apprentices and shop trainees. (a) Agencies may establish special wage schedules for apprentices and shop trainees who are included in: (1) Formal apprenticeship programs involving training for...

5 CFR 532.265 - Special wage schedules for apprentices and shop trainees.

Code of Federal Regulations, 2013 CFR

2013-01-01

... and shop trainees. 532.265 Section 532.265 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT... schedules for apprentices and shop trainees. (a) Agencies may establish special wage schedules for apprentices and shop trainees who are included in: (1) Formal apprenticeship programs involving training for...

5 CFR 532.265 - Special wage schedules for apprentices and shop trainees.

Code of Federal Regulations, 2014 CFR

2014-01-01

... and shop trainees. 532.265 Section 532.265 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT... schedules for apprentices and shop trainees. (a) Agencies may establish special wage schedules for apprentices and shop trainees who are included in: (1) Formal apprenticeship programs involving training for...

5 CFR 532.265 - Special wage schedules for apprentices and shop trainees.

Code of Federal Regulations, 2011 CFR

2011-01-01

... and shop trainees. 532.265 Section 532.265 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT... schedules for apprentices and shop trainees. (a) Agencies may establish special wage schedules for apprentices and shop trainees who are included in: (1) Formal apprenticeship programs involving training for...

40 CFR 265.382 - Open burning; waste explosives.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Open burning; waste explosives. 265... DISPOSAL FACILITIES Thermal Treatment § 265.382 Open burning; waste explosives. Open burning of hazardous waste is prohibited except for the open burning and detonation of waste explosives. Waste explosives...

40 CFR 265.382 - Open burning; waste explosives.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Open burning; waste explosives. 265... DISPOSAL FACILITIES Thermal Treatment § 265.382 Open burning; waste explosives. Open burning of hazardous waste is prohibited except for the open burning and detonation of waste explosives. Waste explosives...

40 CFR 265.382 - Open burning; waste explosives.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Open burning; waste explosives. 265... DISPOSAL FACILITIES Thermal Treatment § 265.382 Open burning; waste explosives. Open burning of hazardous waste is prohibited except for the open burning and detonation of waste explosives. Waste explosives...

40 CFR 265.382 - Open burning; waste explosives.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Open burning; waste explosives. 265... DISPOSAL FACILITIES Thermal Treatment § 265.382 Open burning; waste explosives. Open burning of hazardous waste is prohibited except for the open burning and detonation of waste explosives. Waste explosives...

40 CFR 265.382 - Open burning; waste explosives.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Open burning; waste explosives. 265... DISPOSAL FACILITIES Thermal Treatment § 265.382 Open burning; waste explosives. Open burning of hazardous waste is prohibited except for the open burning and detonation of waste explosives. Waste explosives...

40 CFR 265.35 - Required aisle space.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Required aisle space. 265.35 Section... FACILITIES Preparedness and Prevention § 265.35 Required aisle space. The owner or operator must maintain aisle space to allow the unobstructed movement of personnel, fire protection equipment, spill control...

40 CFR 265.35 - Required aisle space.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Required aisle space. 265.35 Section... FACILITIES Preparedness and Prevention § 265.35 Required aisle space. The owner or operator must maintain aisle space to allow the unobstructed movement of personnel, fire protection equipment, spill control...

40 CFR 265.35 - Required aisle space.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Required aisle space. 265.35 Section... FACILITIES Preparedness and Prevention § 265.35 Required aisle space. The owner or operator must maintain aisle space to allow the unobstructed movement of personnel, fire protection equipment, spill control...

40 CFR 265.35 - Required aisle space.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Required aisle space. 265.35 Section... FACILITIES Preparedness and Prevention § 265.35 Required aisle space. The owner or operator must maintain aisle space to allow the unobstructed movement of personnel, fire protection equipment, spill control...

40 CFR 265.35 - Required aisle space.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Required aisle space. 265.35 Section... FACILITIES Preparedness and Prevention § 265.35 Required aisle space. The owner or operator must maintain aisle space to allow the unobstructed movement of personnel, fire protection equipment, spill control...

15 CFR 265.12 - Speeding or reckless driving.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Speeding or reckless driving. 265.12 Section 265.12 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE REGULATIONS GOVERNING TRAFFIC AND CONDUCT...

40 CFR 265.54 - Amendment of contingency plan.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Amendment of contingency plan. 265.54... DISPOSAL FACILITIES Contingency Plan and Emergency Procedures § 265.54 Amendment of contingency plan. The contingency plan must be reviewed, and immediately amended, if necessary, whenever: (a) Applicable regulations...

40 CFR 265.54 - Amendment of contingency plan.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Amendment of contingency plan. 265.54... DISPOSAL FACILITIES Contingency Plan and Emergency Procedures § 265.54 Amendment of contingency plan. The contingency plan must be reviewed, and immediately amended, if necessary, whenever: (a) Applicable regulations...

5 CFR 532.265 - Special wage schedules for apprentices and shop trainees.

Code of Federal Regulations, 2010 CFR

2010-01-01

... and shop trainees. 532.265 Section 532.265 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT... schedules for apprentices and shop trainees. (a) Agencies may establish special wage schedules for apprentices and shop trainees who are included in: (1) Formal apprenticeship programs involving training for...

40 CFR 265.1087 - Standards: Containers.

Code of Federal Regulations, 2013 CFR

2013-07-01

... integral part of the container structural design (e.g., a “portable tank” or bulk cargo container equipped... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Standards: Containers. 265.1087... DISPOSAL FACILITIES Air Emission Standards for Tanks, Surface Impoundments, and Containers § 265.1087...

40 CFR 265.1087 - Standards: Containers.

Code of Federal Regulations, 2014 CFR

2014-07-01

... integral part of the container structural design (e.g., a “portable tank” or bulk cargo container equipped... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Standards: Containers. 265.1087... DISPOSAL FACILITIES Air Emission Standards for Tanks, Surface Impoundments, and Containers § 265.1087...

40 CFR 265.1087 - Standards: Containers.

Code of Federal Regulations, 2012 CFR

2012-07-01

... integral part of the container structural design (e.g., a “portable tank” or bulk cargo container equipped... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Standards: Containers. 265.1087... DISPOSAL FACILITIES Air Emission Standards for Tanks, Surface Impoundments, and Containers § 265.1087...

40 CFR 265.1087 - Standards: Containers.

Code of Federal Regulations, 2011 CFR

2011-07-01

... integral part of the container structural design (e.g., a “portable tank” or bulk cargo container equipped... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Standards: Containers. 265.1087... DISPOSAL FACILITIES Air Emission Standards for Tanks, Surface Impoundments, and Containers § 265.1087...

40 CFR 265.1090 - Recordkeeping requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... DISPOSAL FACILITIES Air Emission Standards for Tanks, Surface Impoundments, and Containers § 265.1090... containers using Container Level 3 air emission controls in accordance with the requirements of § 265.1087 of... section when the tank, surface impoundment, or container is or would be operating at capacity or the...

40 CFR 265.1090 - Recordkeeping requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... DISPOSAL FACILITIES Air Emission Standards for Tanks, Surface Impoundments, and Containers § 265.1090... containers using Container Level 3 air emission controls in accordance with the requirements of § 265.1087 of... section when the tank, surface impoundment, or container is or would be operating at capacity or the...

40 CFR 265.11 - Identification number.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Identification number. 265.11 Section... FACILITIES General Facility Standards § 265.11 Identification number. Every facility owner or operator must apply to EPA for an EPA identification number in accordance with the EPA notification procedures (45 FR...

40 CFR 265.11 - Identification number.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Identification number. 265.11 Section... FACILITIES General Facility Standards § 265.11 Identification number. Every facility owner or operator must apply to EPA for an EPA identification number in accordance with the EPA notification procedures (45 FR...

40 CFR 265.11 - Identification number.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Identification number. 265.11 Section... FACILITIES General Facility Standards § 265.11 Identification number. Every facility owner or operator must apply to EPA for an EPA identification number in accordance with the EPA notification procedures (45 FR...

40 CFR 265.11 - Identification number.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Identification number. 265.11 Section... FACILITIES General Facility Standards § 265.11 Identification number. Every facility owner or operator must apply to EPA for an EPA identification number in accordance with the EPA notification procedures (45 FR...

40 CFR 265.11 - Identification number.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Identification number. 265.11 Section... FACILITIES General Facility Standards § 265.11 Identification number. Every facility owner or operator must apply to EPA for an EPA identification number in accordance with the EPA notification procedures (45 FR...

18 CFR 284.265 - Cost recovery by interstate pipeline.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 1978 AND RELATED AUTHORITIES Emergency Natural Gas Sale, Transportation, and Exchange Transactions... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Cost recovery by interstate pipeline. 284.265 Section 284.265 Conservation of Power and Water Resources FEDERAL ENERGY...

40 CFR 265.54 - Amendment of contingency plan.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Amendment of contingency plan. 265.54... DISPOSAL FACILITIES Contingency Plan and Emergency Procedures § 265.54 Amendment of contingency plan. The contingency plan must be reviewed, and immediately amended, if necessary, whenever: (a) Applicable regulations...

Low cost silicon solar array project large area silicon sheet task: Silicon web process development

NASA Technical Reports Server (NTRS)

Duncan, C. S.; Seidensticker, R. G.; Mchugh, J. P.; Blais, P. D.; Davis, J. R., Jr.

1977-01-01

Growth configurations were developed which produced crystals having low residual stress levels. The properties of a 106 mm diameter round crucible were evaluated and it was found that this design had greatly enhanced temperature fluctuations arising from convection in the melt. Thermal modeling efforts were directed to developing finite element models of the 106 mm round crucible and an elongated susceptor/crucible configuration. Also, the thermal model for the heat loss modes from the dendritic web was examined for guidance in reducing the thermal stress in the web. An economic analysis was prepared to evaluate the silicon web process in relation to price goals.

Energy spectra of cosmic-ray nuclei from 50 to 2000 GeV per amu

NASA Technical Reports Server (NTRS)

Grunsfeld, John M.; L'Heureux, Jacques; Meyer, Peter; Muller, Dietrich; Swordy, Simon P.

1988-01-01

A direct measurement of the elemental composition of cosmic rays up to energies of several TeV/amu was performed during the Spacelab 2 flight of the Space Shuttle. Results on the spectral shape for the elements C, O, Ne, Mg, Si, and Fe, obtained from this experiment, are presented. It was found that the C and O energy spectra retain a power-law spectrum in energy with an exponent Gamma of about 2.65. The Fe spectrum is flatter (Gamma of about 2.55) up to a particle energy of about 10 to the 14th eV, indicating a steady increase in the relative abundance of iron in cosmic rays up to this energy. The energy spectra of Ne, Mg, and Si are steeper than anticipated. This behavior is unexpected within current models of cosmic-ray acceleration.

30 CFR 1206.265 - Value enhancement of marketable coal.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Value enhancement of marketable coal. 1206.265... INTERIOR Natural Resources Revenue PRODUCT VALUATION Federal Coal § 1206.265 Value enhancement of marketable coal. If, prior to use, sale, or other disposition, the lessee enhances the value of coal after...

40 CFR 265.114 - Disposal or decontamination of equipment, structures and soils.

Code of Federal Regulations, 2010 CFR

2010-07-01

... equipment, structures and soils. 265.114 Section 265.114 Protection of Environment ENVIRONMENTAL PROTECTION... decontamination of equipment, structures and soils. During the partial and final closure periods, all contaminated equipment, structures and soil must be properly disposed of, or decontaminated unless specified otherwise in...

40 CFR 265.114 - Disposal or decontamination of equipment, structures and soils.

Code of Federal Regulations, 2012 CFR

2012-07-01

... equipment, structures and soils. 265.114 Section 265.114 Protection of Environment ENVIRONMENTAL PROTECTION... decontamination of equipment, structures and soils. During the partial and final closure periods, all contaminated equipment, structures and soil must be properly disposed of, or decontaminated unless specified otherwise in...

40 CFR 265.114 - Disposal or decontamination of equipment, structures and soils.

Code of Federal Regulations, 2011 CFR

2011-07-01

... equipment, structures and soils. 265.114 Section 265.114 Protection of Environment ENVIRONMENTAL PROTECTION... decontamination of equipment, structures and soils. During the partial and final closure periods, all contaminated equipment, structures and soil must be properly disposed of, or decontaminated unless specified otherwise in...

40 CFR 265.114 - Disposal or decontamination of equipment, structures and soils.

Code of Federal Regulations, 2013 CFR

2013-07-01

... equipment, structures and soils. 265.114 Section 265.114 Protection of Environment ENVIRONMENTAL PROTECTION... decontamination of equipment, structures and soils. During the partial and final closure periods, all contaminated equipment, structures and soil must be properly disposed of, or decontaminated unless specified otherwise in...

40 CFR 265.114 - Disposal or decontamination of equipment, structures and soils.

Code of Federal Regulations, 2014 CFR

2014-07-01

... equipment, structures and soils. 265.114 Section 265.114 Protection of Environment ENVIRONMENTAL PROTECTION... decontamination of equipment, structures and soils. During the partial and final closure periods, all contaminated equipment, structures and soil must be properly disposed of, or decontaminated unless specified otherwise in...

12 CFR 265.2 - Delegation of functions generally.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Delegation of functions generally. 265.2... RESERVE SYSTEM RULES REGARDING DELEGATION OF AUTHORITY § 265.2 Delegation of functions generally. (a) The Board has determined to delegate authority to exercise the functions described in this part. (b) The...

40 CFR 265.117 - Post-closure care and use of property.

Code of Federal Regulations, 2010 CFR

2010-07-01

.... 265.117 Section 265.117 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID.... (a)(1) Post-closure care for each hazardous waste management unit subject to the requirements of... this part. (2) Any time preceding closure of a hazardous waste management unit subject to post-closure...

14 CFR 125.265 - Flight engineer requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Flight engineer requirements. 125.265... Requirements § 125.265 Flight engineer requirements. (a) No person may operate an airplane for which a flight engineer is required by the type certification requirements without a flight crewmember holding a current...

14 CFR 125.265 - Flight engineer requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Flight engineer requirements. 125.265... Requirements § 125.265 Flight engineer requirements. (a) No person may operate an airplane for which a flight engineer is required by the type certification requirements without a flight crewmember holding a current...

14 CFR 125.265 - Flight engineer requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Flight engineer requirements. 125.265... Requirements § 125.265 Flight engineer requirements. (a) No person may operate an airplane for which a flight engineer is required by the type certification requirements without a flight crewmember holding a current...

15 CFR 265.13 - Emergency vehicles.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Emergency vehicles. 265.13 Section 265.13 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE... Emergency vehicles. No person shall fail or refuse to yield the right-of-way to an emergency vehicle when...

15 CFR 265.13 - Emergency vehicles.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Emergency vehicles. 265.13 Section 265.13 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE... Emergency vehicles. No person shall fail or refuse to yield the right-of-way to an emergency vehicle when...

15 CFR 265.13 - Emergency vehicles.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Emergency vehicles. 265.13 Section 265.13 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE... Emergency vehicles. No person shall fail or refuse to yield the right-of-way to an emergency vehicle when...

15 CFR 265.13 - Emergency vehicles.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Emergency vehicles. 265.13 Section 265.13 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE... Emergency vehicles. No person shall fail or refuse to yield the right-of-way to an emergency vehicle when...

15 CFR 265.13 - Emergency vehicles.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Emergency vehicles. 265.13 Section 265.13 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE... Emergency vehicles. No person shall fail or refuse to yield the right-of-way to an emergency vehicle when...

40 CFR 265.91 - Ground-water monitoring system.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Ground-water monitoring system. 265.91... DISPOSAL FACILITIES Ground-Water Monitoring § 265.91 Ground-water monitoring system. (a) A ground-water monitoring system must be capable of yielding ground-water samples for analysis and must consist of: (1...

15 CFR 265.39 - Weapons and explosives.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Weapons and explosives. 265.39 Section..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.39 Weapons and... dangerous or deadly weapons or materials, or explosives, either openly or concealed, without the written...

15 CFR 265.39 - Weapons and explosives.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Weapons and explosives. 265.39 Section..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.39 Weapons and... dangerous or deadly weapons or materials, or explosives, either openly or concealed, without the written...

15 CFR 265.39 - Weapons and explosives.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Weapons and explosives. 265.39 Section..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.39 Weapons and... dangerous or deadly weapons or materials, or explosives, either openly or concealed, without the written...

15 CFR 265.39 - Weapons and explosives.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Weapons and explosives. 265.39 Section..., GAITHERSBURG, MARYLAND, AND BOULDER AND FORT COLLINS, COLORADO Buildings and Grounds § 265.39 Weapons and... dangerous or deadly weapons or materials, or explosives, either openly or concealed, without the written...

24 CFR 241.265 - Insurance of property against flood.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Insurance of property against flood. 241.265 Section 241.265 Housing and Urban Development Regulations Relating to Housing and Urban... Insurance of property against flood. The mortgaged property shall be insured against flood as stipulated by...

15 CFR 265.42 - Photography for advertising or commercial purposes; advertising and soliciting.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Photography for advertising or commercial purposes; advertising and soliciting. 265.42 Section 265.42 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF...

21 CFR 26.5 - Length of transition period.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Length of transition period. 26.5 Section 26.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL MUTUAL RECOGNITION OF PHARMACEUTICAL GOOD MANUFACTURING PRACTICE REPORTS, MEDICAL DEVICE QUALITY SYSTEM AUDIT REPORTS...

40 CFR 265.171 - Condition of containers.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Condition of containers. 265.171... DISPOSAL FACILITIES Use and Management of Containers § 265.171 Condition of containers. If a container... transfer the hazardous waste from this container to a container that is in good condition, or manage the...

40 CFR 265.173 - Management of containers.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Management of containers. 265.173... DISPOSAL FACILITIES Use and Management of Containers § 265.173 Management of containers. (a) A container... waste. (b) A container holding hazardous waste must not be opened, handled, or stored in a manner which...

40 CFR 265.51 - Purpose and implementation of contingency plan.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Purpose and implementation of contingency plan. 265.51 Section 265.51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... contingency plan must be designed to minimize hazards to human health or the environment from fires...

40 CFR 265.281 - Special requirements for ignitable or reactive waste.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Special requirements for ignitable or reactive waste. 265.281 Section 265.281 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... waste is immediately incorporated into the soil so that: (1) The resulting waste, mixture, or...

14 CFR 125.265 - Flight engineer requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Flight engineer requirements. 125.265... Requirements § 125.265 Flight engineer requirements. (a) No person may operate an airplane for which a flight engineer is required by the type certification requirements without a flight crewmember holding a current...

14 CFR 125.265 - Flight engineer requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Flight engineer requirements. 125.265... Requirements § 125.265 Flight engineer requirements. (a) No person may operate an airplane for which a flight engineer is required by the type certification requirements without a flight crewmember holding a current...

29 CFR 1952.265 - Level of Federal enforcement.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Level of Federal enforcement. 1952.265 Section 1952.265 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION... Level of Federal enforcement. Pursuant to §§ 1902.20(b)(1)(iii) and 1954.3 of this chapter under which...

25 CFR 265.3 - Roads prohibited.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 1 2013-04-01 2013-04-01 false Roads prohibited. 265.3 Section 265.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HERITAGE PRESERVATION ESTABLISHMENT OF ROADLESS AND WILD AREAS..., unless the requirements of fire protection, commercial use for the Indians' benefit or actual needs of...

25 CFR 265.3 - Roads prohibited.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 1 2012-04-01 2011-04-01 true Roads prohibited. 265.3 Section 265.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HERITAGE PRESERVATION ESTABLISHMENT OF ROADLESS AND WILD AREAS..., unless the requirements of fire protection, commercial use for the Indians' benefit or actual needs of...

25 CFR 265.3 - Roads prohibited.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false Roads prohibited. 265.3 Section 265.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HERITAGE PRESERVATION ESTABLISHMENT OF ROADLESS AND WILD AREAS..., unless the requirements of fire protection, commercial use for the Indians' benefit or actual needs of...

25 CFR 265.3 - Roads prohibited.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 1 2014-04-01 2014-04-01 false Roads prohibited. 265.3 Section 265.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HERITAGE PRESERVATION ESTABLISHMENT OF ROADLESS AND WILD AREAS..., unless the requirements of fire protection, commercial use for the Indians' benefit or actual needs of...

25 CFR 265.3 - Roads prohibited.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Roads prohibited. 265.3 Section 265.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HERITAGE PRESERVATION ESTABLISHMENT OF ROADLESS AND WILD AREAS..., unless the requirements of fire protection, commercial use for the Indians' benefit or actual needs of...

40 CFR 265.91 - Ground-water monitoring system.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Ground-water monitoring system. 265.91... DISPOSAL FACILITIES Ground-Water Monitoring § 265.91 Ground-water monitoring system. (a) A ground-water monitoring system must be capable of yielding ground-water samples for analysis and must consist of: (1...

40 CFR 265.91 - Ground-water monitoring system.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Ground-water monitoring system. 265.91... DISPOSAL FACILITIES Ground-Water Monitoring § 265.91 Ground-water monitoring system. (a) A ground-water monitoring system must be capable of yielding ground-water samples for analysis and must consist of: (1...

40 CFR 265.91 - Ground-water monitoring system.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Ground-water monitoring system. 265.91... DISPOSAL FACILITIES Ground-Water Monitoring § 265.91 Ground-water monitoring system. (a) A ground-water monitoring system must be capable of yielding ground-water samples for analysis and must consist of: (1...

40 CFR 761.265 - Sampling bulk PCB remediation waste and porous surfaces.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Sampling bulk PCB remediation waste and porous surfaces. 761.265 Section 761.265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY..., DISTRIBUTION IN COMMERCE, AND USE PROHIBITIONS Cleanup Site Characterization Sampling for PCB Remediation Waste...

40 CFR 761.265 - Sampling bulk PCB remediation waste and porous surfaces.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Sampling bulk PCB remediation waste and porous surfaces. 761.265 Section 761.265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY..., DISTRIBUTION IN COMMERCE, AND USE PROHIBITIONS Cleanup Site Characterization Sampling for PCB Remediation Waste...

40 CFR 761.265 - Sampling bulk PCB remediation waste and porous surfaces.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Sampling bulk PCB remediation waste and porous surfaces. 761.265 Section 761.265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY..., DISTRIBUTION IN COMMERCE, AND USE PROHIBITIONS Cleanup Site Characterization Sampling for PCB Remediation Waste...

40 CFR 761.265 - Sampling bulk PCB remediation waste and porous surfaces.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Sampling bulk PCB remediation waste and porous surfaces. 761.265 Section 761.265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY..., DISTRIBUTION IN COMMERCE, AND USE PROHIBITIONS Cleanup Site Characterization Sampling for PCB Remediation Waste...

33 CFR 105.265 - Security measures for handling cargo.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., containers, or other cargo transport units entering the facility match the delivery note or equivalent cargo..., containers or other cargo transport units, and cargo storage areas within the facility for evidence of... cargo. 105.265 Section 105.265 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND...

33 CFR 105.265 - Security measures for handling cargo.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., containers, or other cargo transport units entering the facility match the delivery note or equivalent cargo..., containers or other cargo transport units, and cargo storage areas within the facility for evidence of... cargo. 105.265 Section 105.265 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND...

33 CFR 105.265 - Security measures for handling cargo.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., containers, or other cargo transport units entering the facility match the delivery note or equivalent cargo..., containers or other cargo transport units, and cargo storage areas within the facility for evidence of... cargo. 105.265 Section 105.265 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND...

33 CFR 105.265 - Security measures for handling cargo.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., containers, or other cargo transport units entering the facility match the delivery note or equivalent cargo..., containers or other cargo transport units, and cargo storage areas within the facility for evidence of... cargo. 105.265 Section 105.265 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND...

33 CFR 105.265 - Security measures for handling cargo.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., containers, or other cargo transport units entering the facility match the delivery note or equivalent cargo..., containers or other cargo transport units, and cargo storage areas within the facility for evidence of... cargo. 105.265 Section 105.265 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND...

5. PART 2 OF 3 PART PANORAMA WITH NOS. CA265J4 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. PART 2 OF 3 PART PANORAMA WITH NOS. CA-265-J-4 AND CA-265-J-6 OF FIGUEROA STREET AND LOS ANGELES RIVER VIADUCTS. LOOKING 308°W. - Arroyo Seco Parkway, Figueroa Street Viaduct, Spanning Los Angeles River, Los Angeles, Los Angeles County, CA

40 CFR 265.402 - Waste analysis and trial tests.

Code of Federal Regulations, 2013 CFR

2013-07-01

... waste analysis and trial test, or the documented information, in the operating record of the facility.] ... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Waste analysis and trial tests. 265... DISPOSAL FACILITIES Chemical, Physical, and Biological Treatment § 265.402 Waste analysis and trial tests...

40 CFR 265.402 - Waste analysis and trial tests.

Code of Federal Regulations, 2014 CFR

2014-07-01

... waste analysis and trial test, or the documented information, in the operating record of the facility.] ... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Waste analysis and trial tests. 265... DISPOSAL FACILITIES Chemical, Physical, and Biological Treatment § 265.402 Waste analysis and trial tests...

40 CFR 265.402 - Waste analysis and trial tests.

Code of Federal Regulations, 2012 CFR

2012-07-01

... waste analysis and trial test, or the documented information, in the operating record of the facility.] ... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Waste analysis and trial tests. 265... DISPOSAL FACILITIES Chemical, Physical, and Biological Treatment § 265.402 Waste analysis and trial tests...

31 CFR 26.5 - Upgrades and additional environmental information.

Code of Federal Regulations, 2010 CFR

2010-07-01

... information. 26.5 Section 26.5 Money and Finance: Treasury Office of the Secretary of the Treasury... environmental information. (a) Environmental category upgrades. If the WGMA and the Department of the Treasury... environmental analysis planned by the MDB is insufficient, the Department of the Treasury will instruct the...

31 CFR 26.5 - Upgrades and additional environmental information.

Code of Federal Regulations, 2013 CFR

2013-07-01

... information. 26.5 Section 26.5 Money and Finance: Treasury Office of the Secretary of the Treasury... environmental information. (a) Environmental category upgrades. If the WGMA and the Department of the Treasury... environmental analysis planned by the MDB is insufficient, the Department of the Treasury will instruct the...

40 CFR 265.402 - Waste analysis and trial tests.

Code of Federal Regulations, 2010 CFR

2010-07-01

... waste analysis and trial test, or the documented information, in the operating record of the facility.] ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Waste analysis and trial tests. 265... DISPOSAL FACILITIES Chemical, Physical, and Biological Treatment § 265.402 Waste analysis and trial tests...

31 CFR 26.5 - Upgrades and additional environmental information.

Code of Federal Regulations, 2014 CFR

2014-07-01

... information. 26.5 Section 26.5 Money and Finance: Treasury Office of the Secretary of the Treasury... environmental information. (a) Environmental category upgrades. If the WGMA and the Department of the Treasury... environmental analysis planned by the MDB is insufficient, the Department of the Treasury will instruct the...

40 CFR 265.402 - Waste analysis and trial tests.

Code of Federal Regulations, 2011 CFR

2011-07-01

... waste analysis and trial test, or the documented information, in the operating record of the facility.] ... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Waste analysis and trial tests. 265... DISPOSAL FACILITIES Chemical, Physical, and Biological Treatment § 265.402 Waste analysis and trial tests...

40 CFR 265.229 - Special requirements for ignitable or reactive waste.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Special requirements for ignitable or reactive waste. 265.229 Section 265.229 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... qualified chemist or engineer that, to the best of his knowledge and opinion, the design features or...

40 CFR 265.13 - General waste analysis.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false General waste analysis. 265.13 Section... FACILITIES General Facility Standards § 265.13 General waste analysis. (a)(1) Before an owner or operator...(d), he must obtain a detailed chemical and physical analysis of a representative sample of the...

20 CFR 416.265 - Requirements for the special SSI eligibility status.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Requirements for the special SSI eligibility status. 416.265 Section 416.265 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

20 CFR 416.265 - Requirements for the special SSI eligibility status.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Requirements for the special SSI eligibility status. 416.265 Section 416.265 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

20 CFR 416.265 - Requirements for the special SSI eligibility status.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Requirements for the special SSI eligibility status. 416.265 Section 416.265 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Eligibility Special Provisions for People Who Work Despite A...

6. SITE OVERVIEW. PART 1 OF 6 PART PANORAMA WITH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. SITE OVERVIEW. PART 1 OF 6 PART PANORAMA WITH NOS. CA-265-7 TO CA-265-11. ARROYO SECO PARKWAY AS SEEN FROM RADIO TOWER HILL (APPROXIMATELY 34° 5' BY 118° 12'30" ON USGS LOS ANGELES QUADRANGLE). PART 1 SHOWS GRAND VIEW POINT AT RIGHT REAR (LOCATION OF CAMERA POSITION FOR PHOTOGRAPHS NOS. 265-1 TO CA-265-5) AND FIGUEROA VIADUCT OVERCROSSING; DOWNTOWN LOS ANGELES IS AT LEFT REAR. LOOKING 234° SW. - Arroyo Seco Parkway, Los Angeles to Pasadena, Los Angeles, Los Angeles County, CA

Design and fabrication of continuous-profile diffractive micro-optical elements as a beam splitter.

PubMed

Feng, Di; Yan, Yingbai; Jin, Guofan; Fan, Shoushan

2004-10-10

An optimization algorithm that combines a rigorous electromagnetic computation model with an effective iterative method is utilized to design diffractive micro-optical elements that exhibit fast convergence and better design quality. The design example is a two-dimensional 1-to-2 beam splitter that can symmetrically generate two focal lines separated by 80 microm at the observation plane with a small angle separation of +/- 16 degrees. Experimental results are presented for an element with continuous profiles fabricated into a monocrystalline silicon substrate that has a width of 160 microm and a focal length of 140 microm at a free-space wavelength of 10.6 microm.

[Determination of eight trace elements in the Swertia davidii Franch by flame atomic absorption spectrometry].

PubMed

Li, Tao; Wang, Yuan-zhong; Yu, Hon; Cao, Yu-juan; Zhang, Jing-jing; Liu, Qin

2007-12-01

The effects of different sample digestives on the determination of Swertia davidii Franch are compared. Eight trace elements in the Swertia davidii Franch were determined by flame atomic absorption spectrometry. The result shows that the RSD and recovery are better if the Swertia davidii Franch was digested with HNO3-HClO4 (5 : 1) mixed acid. The experimental results show that the detection limits were all smaller than 0.097 microg x mL(-1), the RSDs (n=8) all smaller than 2.34%, and the addition standard recovery (ASR) (n=8) was 89.32%-106.65% for all the elements.

Top 1% of Inpatients Administered Antimicrobial Agents Comprising 50% of Expenditures: A Descriptive Study and Opportunities for Stewardship Intervention.

PubMed

Dela-Pena, Jennifer; Kerstenetzky, Luiza; Schulz, Lucas; Kendall, Ron; Lepak, Alexander; Fox, Barry

2017-03-01

OBJECTIVE To characterize the top 1% of inpatients who contributed to the 6-month antimicrobial budget in a tertiary, academic medical center and identify cost-effective intervention opportunities targeting high-cost antimicrobial utilization. DESIGN Retrospective cohort study. PATIENTS Top 1% of the antimicrobial budget from July 1 through December 31, 2014. METHODS Patients were identified through a pharmacy billing database. Baseline characteristics were collected through a retrospective medical chart review. Patients were presented to the antimicrobial stewardship team to determine appropriate utilization of high-cost antimicrobials and potential intervention opportunities. Appropriate use was defined as antimicrobial therapy that was effective, safe, and most cost-effective compared with alternative agents. RESULTS A total of 10,460 patients received antimicrobials in 6 months; 106 patients accounted for $889,543 (47.2%) of the antimicrobial budget with an antimicrobial cost per day of $219±$192 and antimicrobial cost per admission of $4,733±$7,614. Most patients were immunocompromised (75%) and were followed by the infectious disease consult service (80%). The most commonly prescribed antimicrobials for treatment were daptomycin, micafungin, liposomal amphotericin B, and meropenem. Posaconazole and valganciclovir accounted for most of the prophylactic therapy. Cost-effective opportunities (n=71) were present in 57 (54%) of 106 patients, which included dose optimization, de-escalation, dosage form conversion, and improvement in transitions of care. CONCLUSION Antimicrobial stewardship oversight is important in implementing cost-effective strategies, especially in complex and immunocompromised patients who require the use of high-cost antimicrobials. Infect Control Hosp Epidemiol 2017;38:259-265.

Responses to Comments

DTIC Science & Technology

1989-04-01

34, New Phytology ., Vol. 79, pp 95-106. Davis, R. D., and P. H. T. Beckett. 1978. "Upper Critical Levels of Toxic Elements in Plants. II. Critical...Levels of Copper in Young Barley, Wheat, Rape, Lettuce, and Ryegrass, and of Nickel and Zinc in Young Barley and Ryegrass", New Phytology , Vol. 80, pp 23

30 CFR 206.265 - Value enhancement of marketable coal.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Value enhancement of marketable coal. 206.265... MANAGEMENT PRODUCT VALUATION Federal Coal § 206.265 Value enhancement of marketable coal. If, prior to use, sale, or other disposition, the lessee enhances the value of coal after the coal has been placed in...

30 CFR 1206.265 - Value enhancement of marketable coal.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 3 2014-07-01 2014-07-01 false Value enhancement of marketable coal. 1206.265... RESOURCES REVENUE PRODUCT VALUATION Federal Coal § 1206.265 Value enhancement of marketable coal. If, prior to use, sale, or other disposition, the lessee enhances the value of coal after the coal has been...

30 CFR 1206.265 - Value enhancement of marketable coal.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Value enhancement of marketable coal. 1206.265... RESOURCES REVENUE PRODUCT VALUATION Federal Coal § 1206.265 Value enhancement of marketable coal. If, prior to use, sale, or other disposition, the lessee enhances the value of coal after the coal has been...

30 CFR 1206.265 - Value enhancement of marketable coal.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 3 2013-07-01 2013-07-01 false Value enhancement of marketable coal. 1206.265... RESOURCES REVENUE PRODUCT VALUATION Federal Coal § 1206.265 Value enhancement of marketable coal. If, prior to use, sale, or other disposition, the lessee enhances the value of coal after the coal has been...

40 CFR 265.92 - Sampling and analysis.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Sampling and analysis. 265.92 Section... FACILITIES Ground-Water Monitoring § 265.92 Sampling and analysis. (a) The owner or operator must obtain and... follow a ground-water sampling and analysis plan. He must keep this plan at the facility. The plan must...

40 CFR 265.92 - Sampling and analysis.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Sampling and analysis. 265.92 Section... FACILITIES Ground-Water Monitoring § 265.92 Sampling and analysis. (a) The owner or operator must obtain and... follow a ground-water sampling and analysis plan. He must keep this plan at the facility. The plan must...

27 CFR 24.265 - Losses by theft.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Losses by theft. 24.265... OF THE TREASURY LIQUORS WINE Losses of Wine § 24.265 Losses by theft. The proprietor shall be liable... to the satisfaction of the appropriate TTB officer that the theft did not occur as the result of...

40 CFR 265.144 - Cost estimate for post-closure care.

Code of Federal Regulations, 2012 CFR

2012-07-01

... comply with § 265.145. For owners or operators using the financial test or corporate guarantee, the post... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Cost estimate for post-closure care..., STORAGE, AND DISPOSAL FACILITIES Financial Requirements § 265.144 Cost estimate for post-closure care. (a...

40 CFR 265.144 - Cost estimate for post-closure care.

Code of Federal Regulations, 2010 CFR

2010-07-01

... comply with § 265.145. For owners or operators using the financial test or corporate guarantee, the post... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Cost estimate for post-closure care..., STORAGE, AND DISPOSAL FACILITIES Financial Requirements § 265.144 Cost estimate for post-closure care. (a...

40 CFR 265.144 - Cost estimate for post-closure care.

Code of Federal Regulations, 2013 CFR

2013-07-01

... comply with § 265.145. For owners or operators using the financial test or corporate guarantee, the post... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Cost estimate for post-closure care..., STORAGE, AND DISPOSAL FACILITIES Financial Requirements § 265.144 Cost estimate for post-closure care. (a...

40 CFR 265.144 - Cost estimate for post-closure care.

Code of Federal Regulations, 2011 CFR

2011-07-01

... comply with § 265.145. For owners or operators using the financial test or corporate guarantee, the post... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Cost estimate for post-closure care..., STORAGE, AND DISPOSAL FACILITIES Financial Requirements § 265.144 Cost estimate for post-closure care. (a...

40 CFR 265.144 - Cost estimate for post-closure care.

Code of Federal Regulations, 2014 CFR

2014-07-01

... comply with § 265.145. For owners or operators using the financial test or corporate guarantee, the post... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Cost estimate for post-closure care..., STORAGE, AND DISPOSAL FACILITIES Financial Requirements § 265.144 Cost estimate for post-closure care. (a...

40 CFR 265.257 - Special requirements for incompatible wastes.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., STORAGE, AND DISPOSAL FACILITIES Waste Piles § 265.257 Special requirements for incompatible wastes. (a... the same pile, unless § 265.17(b) is complied with. (b) A pile of hazardous waste that is incompatible with any waste or other material stored nearby in other containers, piles, open tanks, or surface...

40 CFR 265.252 - Waste analysis.

Code of Federal Regulations, 2010 CFR

2010-07-01

... FACILITIES Waste Piles § 265.252 Waste analysis. In addition to the waste analyses required by § 265.13, the... adding the waste to any existing pile, unless (1) The only wastes the facility receives which are... in the pile to which it is to be added. The analysis conducted must be capable of differentiating...

40 CFR 265.251 - Protection from wind.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Protection from wind. 265.251 Section... FACILITIES Waste Piles § 265.251 Protection from wind. The owner or operator of a pile containing hazardous waste which could be subject to dispersal by wind must cover or otherwise manage the pile so that wind...

40 CFR 265.251 - Protection from wind.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Protection from wind. 265.251 Section... FACILITIES Waste Piles § 265.251 Protection from wind. The owner or operator of a pile containing hazardous waste which could be subject to dispersal by wind must cover or otherwise manage the pile so that wind...

40 CFR 265.251 - Protection from wind.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Protection from wind. 265.251 Section... FACILITIES Waste Piles § 265.251 Protection from wind. The owner or operator of a pile containing hazardous waste which could be subject to dispersal by wind must cover or otherwise manage the pile so that wind...

45 CFR 153.265 - Restrictions on use of reinsurance funds for administrative expenses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 1 2014-10-01 2014-10-01 false Restrictions on use of reinsurance funds for administrative expenses. 153.265 Section 153.265 Public Welfare Department of Health and Human Services REQUIREMENTS RELATING TO HEALTH CARE ACCESS STANDARDS RELATED TO REINSURANCE, RISK CORRIDORS, AND RISK...

12 CFR 265.8 - Functions delegated to the Staff Director of the Division of International Finance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... the Division of International Finance. 265.8 Section 265.8 Banks and Banking FEDERAL RESERVE SYSTEM... Functions delegated to the Staff Director of the Division of International Finance. The Board's Staff Director of the Division of International Finance (or the Director's delegee) is authorized: (a...

40 CFR 265.442 - Design and installation of new drip pads.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Design and installation of new drip pads. 265.442 Section 265.442 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Drip Pads §...

40 CFR 265.1064 - Recordkeeping requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

...). (iii) Type of equipment (e.g., a pump or pipeline valve). (iv) Percent-by-weight total organics in the...)(2), an implementation schedule as specified in § 265.1033(a)(2). (3) Where an owner or operator... concentration achieved by the control device, a performance test plan as specified in § 265.1035(b)(3). (4...

40 CFR 265.1064 - Recordkeeping requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

...). (iii) Type of equipment (e.g., a pump or pipeline valve). (iv) Percent-by-weight total organics in the...)(2), an implementation schedule as specified in § 265.1033(a)(2). (3) Where an owner or operator... concentration achieved by the control device, a performance test plan as specified in § 265.1035(b)(3). (4...

40 CFR 265.1064 - Recordkeeping requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

...). (iii) Type of equipment (e.g., a pump or pipeline valve). (iv) Percent-by-weight total organics in the...)(2), an implementation schedule as specified in § 265.1033(a)(2). (3) Where an owner or operator... concentration achieved by the control device, a performance test plan as specified in § 265.1035(b)(3). (4...

40 CFR 265.1064 - Recordkeeping requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

...). (iii) Type of equipment (e.g., a pump or pipeline valve). (iv) Percent-by-weight total organics in the...)(2), an implementation schedule as specified in § 265.1033(a)(2). (3) Where an owner or operator... concentration achieved by the control device, a performance test plan as specified in § 265.1035(b)(3). (4...

40 CFR 265.53 - Copies of contingency plan.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Copies of contingency plan. 265.53... DISPOSAL FACILITIES Contingency Plan and Emergency Procedures § 265.53 Copies of contingency plan. A copy of the contingency plan and all revisions to the plan must be: (a) Maintained at the facility; and (b...

40 CFR 265.53 - Copies of contingency plan.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Copies of contingency plan. 265.53... DISPOSAL FACILITIES Contingency Plan and Emergency Procedures § 265.53 Copies of contingency plan. A copy of the contingency plan and all revisions to the plan must be: (a) Maintained at the facility; and (b...

40 CFR 265.53 - Copies of contingency plan.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Copies of contingency plan. 265.53... DISPOSAL FACILITIES Contingency Plan and Emergency Procedures § 265.53 Copies of contingency plan. A copy of the contingency plan and all revisions to the plan must be: (a) Maintained at the facility; and (b...

40 CFR 265.53 - Copies of contingency plan.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Copies of contingency plan. 265.53... DISPOSAL FACILITIES Contingency Plan and Emergency Procedures § 265.53 Copies of contingency plan. A copy of the contingency plan and all revisions to the plan must be: (a) Maintained at the facility; and (b...

21 CFR 1271.265 - Receipt, predistribution shipment, and distribution of an HCT/P.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Receipt, predistribution shipment, and distribution of an HCT/P. 1271.265 Section 1271.265 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND...

40 CFR 265.200 - Waste analysis and trial tests.

Code of Federal Regulations, 2010 CFR

2010-07-01

... operator to place the results from each waste analysis and trial test, or the documented information, in... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Waste analysis and trial tests. 265... DISPOSAL FACILITIES Tank Systems § 265.200 Waste analysis and trial tests. In addition to performing the...

40 CFR 265.225 - Waste analysis and trial tests.

Code of Federal Regulations, 2013 CFR

2013-07-01

... waste analysis and trial test, or the documented information, in the operating record of the facility... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Waste analysis and trial tests. 265... DISPOSAL FACILITIES Surface Impoundments § 265.225 Waste analysis and trial tests. (a) In addition to the...

40 CFR 265.225 - Waste analysis and trial tests.

Code of Federal Regulations, 2010 CFR

2010-07-01

... waste analysis and trial test, or the documented information, in the operating record of the facility... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Waste analysis and trial tests. 265... DISPOSAL FACILITIES Surface Impoundments § 265.225 Waste analysis and trial tests. (a) In addition to the...

40 CFR 265.225 - Waste analysis and trial tests.

Code of Federal Regulations, 2012 CFR

2012-07-01

... waste analysis and trial test, or the documented information, in the operating record of the facility... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Waste analysis and trial tests. 265... DISPOSAL FACILITIES Surface Impoundments § 265.225 Waste analysis and trial tests. (a) In addition to the...

40 CFR 265.225 - Waste analysis and trial tests.

Code of Federal Regulations, 2014 CFR

2014-07-01

... waste analysis and trial test, or the documented information, in the operating record of the facility... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Waste analysis and trial tests. 265... DISPOSAL FACILITIES Surface Impoundments § 265.225 Waste analysis and trial tests. (a) In addition to the...

40 CFR 265.200 - Waste analysis and trial tests.

Code of Federal Regulations, 2013 CFR

2013-07-01

... operator to place the results from each waste analysis and trial test, or the documented information, in... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Waste analysis and trial tests. 265... DISPOSAL FACILITIES Tank Systems § 265.200 Waste analysis and trial tests. In addition to performing the...

40 CFR 265.225 - Waste analysis and trial tests.

Code of Federal Regulations, 2011 CFR

2011-07-01

... waste analysis and trial test, or the documented information, in the operating record of the facility... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Waste analysis and trial tests. 265... DISPOSAL FACILITIES Surface Impoundments § 265.225 Waste analysis and trial tests. (a) In addition to the...

40 CFR 265.200 - Waste analysis and trial tests.

Code of Federal Regulations, 2011 CFR

2011-07-01

... operator to place the results from each waste analysis and trial test, or the documented information, in... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Waste analysis and trial tests. 265... DISPOSAL FACILITIES Tank Systems § 265.200 Waste analysis and trial tests. In addition to performing the...

40 CFR 265.200 - Waste analysis and trial tests.

Code of Federal Regulations, 2012 CFR

2012-07-01

... operator to place the results from each waste analysis and trial test, or the documented information, in... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Waste analysis and trial tests. 265... DISPOSAL FACILITIES Tank Systems § 265.200 Waste analysis and trial tests. In addition to performing the...

40 CFR 265.200 - Waste analysis and trial tests.

Code of Federal Regulations, 2014 CFR

2014-07-01

... operator to place the results from each waste analysis and trial test, or the documented information, in... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Waste analysis and trial tests. 265... DISPOSAL FACILITIES Tank Systems § 265.200 Waste analysis and trial tests. In addition to performing the...

40 CFR 265.383 - Interim status thermal treatment devices burning particular hazardous waste.

Code of Federal Regulations, 2010 CFR

2010-07-01

... devices burning particular hazardous waste. 265.383 Section 265.383 Protection of Environment... status thermal treatment devices burning particular hazardous waste. (a) Owners or operators of thermal treatment devices subject to this subpart may burn EPA Hazardous Wastes FO20, FO21, FO22, FO23, FO26, or...

40 CFR 265.383 - Interim status thermal treatment devices burning particular hazardous waste.

Code of Federal Regulations, 2013 CFR

2013-07-01

... devices burning particular hazardous waste. 265.383 Section 265.383 Protection of Environment... status thermal treatment devices burning particular hazardous waste. (a) Owners or operators of thermal treatment devices subject to this subpart may burn EPA Hazardous Wastes FO20, FO21, FO22, FO23, FO26, or...

40 CFR 265.383 - Interim status thermal treatment devices burning particular hazardous waste.

Code of Federal Regulations, 2014 CFR

2014-07-01

... devices burning particular hazardous waste. 265.383 Section 265.383 Protection of Environment... status thermal treatment devices burning particular hazardous waste. (a) Owners or operators of thermal treatment devices subject to this subpart may burn EPA Hazardous Wastes FO20, FO21, FO22, FO23, FO26, or...

40 CFR 265.383 - Interim status thermal treatment devices burning particular hazardous waste.

Code of Federal Regulations, 2012 CFR

2012-07-01

... devices burning particular hazardous waste. 265.383 Section 265.383 Protection of Environment... status thermal treatment devices burning particular hazardous waste. (a) Owners or operators of thermal treatment devices subject to this subpart may burn EPA Hazardous Wastes FO20, FO21, FO22, FO23, FO26, or...

40 CFR 265.383 - Interim status thermal treatment devices burning particular hazardous waste.

Code of Federal Regulations, 2011 CFR

2011-07-01

... devices burning particular hazardous waste. 265.383 Section 265.383 Protection of Environment... status thermal treatment devices burning particular hazardous waste. (a) Owners or operators of thermal treatment devices subject to this subpart may burn EPA Hazardous Wastes FO20, FO21, FO22, FO23, FO26, or...

40 CFR 265.251 - Protection from wind.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Protection from wind. 265.251 Section... FACILITIES Waste Piles § 265.251 Protection from wind. The owner or operator of a pile containing hazardous waste which could be subject to dispersal by wind must cover or otherwise manage the pile so that wind...

40 CFR 265.251 - Protection from wind.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Protection from wind. 265.251 Section... FACILITIES Waste Piles § 265.251 Protection from wind. The owner or operator of a pile containing hazardous waste which could be subject to dispersal by wind must cover or otherwise manage the pile so that wind...

40 CFR 265.310 - Closure and post-closure care.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Closure and post-closure care. 265.310... DISPOSAL FACILITIES Landfills § 265.310 Closure and post-closure care. (a) At final closure of the landfill... subsoils present. (b) After final closure, the owner or operator must comply with all post-closure...

40 CFR 265.310 - Closure and post-closure care.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Closure and post-closure care. 265.310... DISPOSAL FACILITIES Landfills § 265.310 Closure and post-closure care. (a) At final closure of the landfill... subsoils present. (b) After final closure, the owner or operator must comply with all post-closure...

40 CFR 265.310 - Closure and post-closure care.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Closure and post-closure care. 265.310... DISPOSAL FACILITIES Landfills § 265.310 Closure and post-closure care. (a) At final closure of the landfill... subsoils present. (b) After final closure, the owner or operator must comply with all post-closure...

40 CFR 265.53 - Copies of contingency plan.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Copies of contingency plan. 265.53... DISPOSAL FACILITIES Contingency Plan and Emergency Procedures § 265.53 Copies of contingency plan. A copy of the contingency plan and all revisions to the plan must be: (a) Maintained at the facility; and (b...

Transformation from a Single Antenna to a Series Array Using Push/Pull Origami

PubMed Central

Shah, Syed Imran Hussain

2017-01-01

We propose a push/pull origami antenna, transformable between a single antenna element and a three-element array. In limited space, the proposed origami antenna can work as a single antenna. When the space is not limited and a higher gain is required, the proposed origami antenna can be transformed to a series antenna array by pulling the frame. In order to push the antenna array back to a single antenna, the frame for each antenna element size must be different. The frame and supporting dielectric materials are built using a three-dimensional (3D) printer. The conductive patterns are inkjet-printed on paper. Thus, the proposed origami antenna is built using hybrid printing technology. The 10-dB impedance bandwidth is 2.5–2.65 GHz and 2.48–2.62 GHz for the single-antenna and array mode, respectively, and the peak gains in the single-antenna and array mode are 5.8 dBi and 7.6 dBi, respectively. The proposed antenna can be used for wireless remote-sensing applications. PMID:28846603

The Trehalose Synthesis Pathway Is an Integral Part of the Virulence Composite for Cryptococcus gattii▿ §

PubMed Central

Ngamskulrungroj, Popchai; Himmelreich, Uwe; Breger, Julia A.; Wilson, Christabel; Chayakulkeeree, Methee; Krockenberger, Mark B.; Malik, Richard; Daniel, Heide-Marie; Toffaletti, Dena; Djordjevic, Julianne T.; Mylonakis, Eleftherios; Meyer, Wieland; Perfect, John R.

2009-01-01

The trehalose pathway is essential for stress tolerance and virulence in fungi. We investigated the importance of this pathway for virulence of the pathogenic yeast Cryptococcus gattii using the highly virulent Vancouver Island, Canada, outbreak strain R265. Three genes putatively involved in trehalose biosynthesis, TPS1 (trehalose-6-phosphate [T6P] synthase) and TPS2 (T6P phosphatase), and degradation, NTH1 (neutral trehalose), were deleted in this strain, creating the R265tps1Δ, R265tps2Δ, and R265nth1Δ mutants. As in Cryptococcus neoformans, cellular trehalose was reduced in the R265tps1Δ and R265tps2Δ mutants, which could not grow and died, respectively, at 37°C on yeast extract-peptone-dextrose agar, suggesting that T6P accumulation in R265tps2Δ is directly toxic. Characterizations of the cryptococcal hexokinases and trehalose mutants support their linkage to the control of glycolysis in this species. However, unlike C. neoformans, the C. gattii R265tps1Δ mutant demonstrated, in addition, defects in melanin and capsule production, supporting an influence of T6P on these virulence pathways. Attenuated virulence of the R265tps1Δ mutant was not due solely to its 37°C growth defect, as shown in worm studies and confirmed by suppressor mutants. Furthermore, an intact trehalose pathway controls protein secretion, mating, and cell wall integrity in C. gattii. Thus, the trehalose synthesis pathway plays a central role in the virulence composites of C. gattii through multiple mechanisms. Deletion of NTH1 had no effect on virulence, but inactivation of the synthesis genes, TPS1 and TPS2, has profound effects on survival of C. gattii in the invertebrate and mammalian hosts. These results highlight the central importance of this pathway in the virulence composites of both pathogenic cryptococcal species. PMID:19651856

Differences between Cryptococcus neoformans and Cryptococcus gattii in the Molecular Mechanisms Governing Utilization of D-Amino Acids as the Sole Nitrogen Source

PubMed Central

Chang, Yun C.; Khanal Lamichhane, Ami; Bradley, James; Rodgers, Laura; Ngamskulrungroj, Popchai; Kwon-Chung, Kyung J.

2015-01-01

The ability to grow on media containing certain D-amino acids as a sole nitrogen source is widely utilized to differentiate Cryptococcus gattii from C. neoformans. We used the C. neoformans H99 and C. gattii R265 strains to dissect the mechanisms of D-amino acids utilization. We identified three putative D-amino acid oxidase (DAO) genes in both strains and showed that each DAO gene plays different roles in D-amino acid utilization in each strain. Deletion of DAO2 retarded growth of R265 on eleven D-amino acids suggesting its prominent role on D-amino acid assimilation in R265. All three R265 DAO genes contributed to growth on D-Asn and D-Asp. DAO3 was required for growth and detoxification of D-Glu by both R265 and H99. Although growth of H99 on most D-amino acids was poor, deletion of DAO1 or DAO3 further exacerbated it on four D-amino acids. Overexpression of DAO2 or DAO3 enabled H99 to grow robustly on several D-amino acids suggesting that expression levels of the native DAO genes in H99 were insufficient for growth on D-amino acids. Replacing the H99 DAO2 gene with a single copy of the R265 DAO2 gene also enabled its utilization of several D-amino acids. Results of gene and promoter swaps of the DAO2 genes suggested that enzymatic activity of Dao2 in H99 might be lower compared to the R265 strain. A reduction in virulence was only observed when all DAO genes were deleted in R265 but not in H99 indicating a pathobiologically exclusive role of the DAO genes in R265. These results suggest that C. neoformans and C. gattii divergently evolved in D-amino acid utilization influenced by their major ecological niches. PMID:26132227

46 CFR 107.265 - Special examination in lieu of drydocking for column stabilized units or surface type units when...

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Special examination in lieu of drydocking for column stabilized units or surface type units when specifically approved by the Commandant. 107.265 Section 107.265 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS...

46 CFR 107.265 - Special examination in lieu of drydocking for column stabilized units or surface type units when...

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Special examination in lieu of drydocking for column stabilized units or surface type units when specifically approved by the Commandant. 107.265 Section 107.265 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS...

46 CFR 107.265 - Special examination in lieu of drydocking for column stabilized units or surface type units when...

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Special examination in lieu of drydocking for column stabilized units or surface type units when specifically approved by the Commandant. 107.265 Section 107.265 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS...

46 CFR 107.265 - Special examination in lieu of drydocking for column stabilized units or surface type units when...

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Special examination in lieu of drydocking for column stabilized units or surface type units when specifically approved by the Commandant. 107.265 Section 107.265 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS...

46 CFR 107.265 - Special examination in lieu of drydocking for column stabilized units or surface type units when...

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Special examination in lieu of drydocking for column stabilized units or surface type units when specifically approved by the Commandant. 107.265 Section 107.265 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS...

20 CFR 645.265 - What safeguards are there to ensure that participants in Welfare-to-Work employment activities do...

Code of Federal Regulations, 2010 CFR

2010-04-01

... participants in Welfare-to-Work employment activities do not displace other employees? 645.265 Section 645.265 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROVISIONS GOVERNING WELFARE... ensure that participants in Welfare-to-Work employment activities do not displace other employees? (a) An...

40 CFR 265.1057 - Standards: Valves in gas/vapor service or in light liquid service.

Code of Federal Regulations, 2011 CFR

2011-07-01

....1057 Standards: Valves in gas/vapor service or in light liquid service. (a) Each valve in gas/vapor or... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Standards: Valves in gas/vapor service or in light liquid service. 265.1057 Section 265.1057 Protection of Environment ENVIRONMENTAL...

40 CFR 265.1057 - Standards: Valves in gas/vapor service or in light liquid service.

Code of Federal Regulations, 2010 CFR

2010-07-01

....1057 Standards: Valves in gas/vapor service or in light liquid service. (a) Each valve in gas/vapor or... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Standards: Valves in gas/vapor service or in light liquid service. 265.1057 Section 265.1057 Protection of Environment ENVIRONMENTAL...

40 CFR 265.1057 - Standards: Valves in gas/vapor service or in light liquid service.

Code of Federal Regulations, 2012 CFR

2012-07-01

....1057 Standards: Valves in gas/vapor service or in light liquid service. (a) Each valve in gas/vapor or... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Standards: Valves in gas/vapor service or in light liquid service. 265.1057 Section 265.1057 Protection of Environment ENVIRONMENTAL...

40 CFR 265.1057 - Standards: Valves in gas/vapor service or in light liquid service.

Code of Federal Regulations, 2013 CFR

2013-07-01

....1057 Standards: Valves in gas/vapor service or in light liquid service. (a) Each valve in gas/vapor or... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Standards: Valves in gas/vapor service or in light liquid service. 265.1057 Section 265.1057 Protection of Environment ENVIRONMENTAL...

40 CFR 265.1057 - Standards: Valves in gas/vapor service or in light liquid service.

Code of Federal Regulations, 2014 CFR

2014-07-01

....1057 Standards: Valves in gas/vapor service or in light liquid service. (a) Each valve in gas/vapor or... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Standards: Valves in gas/vapor service or in light liquid service. 265.1057 Section 265.1057 Protection of Environment ENVIRONMENTAL...

Calibration strategies for the determination of stable carbon absolute isotope ratios in a glycine candidate reference material by elemental analyser-isotope ratio mass spectrometry.

PubMed

Dunn, Philip J H; Malinovsky, Dmitry; Goenaga-Infante, Heidi

2015-04-01

We report a methodology for the determination of the stable carbon absolute isotope ratio of a glycine candidate reference material with natural carbon isotopic composition using EA-IRMS. For the first time, stable carbon absolute isotope ratios have been reported using continuous flow rather than dual inlet isotope ratio mass spectrometry. Also for the first time, a calibration strategy based on the use of synthetic mixtures gravimetrically prepared from well characterised, highly (13)C-enriched and (13)C-depleted glycines was developed for EA-IRMS calibration and generation of absolute carbon isotope ratio values traceable to the SI through calibration standards of known purity. A second calibration strategy based on converting the more typically determined delta values on the Vienna PeeDee Belemnite (VPDB) scale using literature values for the absolute carbon isotope ratio of VPDB itself was used for comparison. Both calibration approaches provided results consistent with those previously reported for the same natural glycine using MC-ICP-MS; absolute carbon ratios of 10,649 × 10(-6) with an expanded uncertainty (k = 2) of 24 × 10(-6) and 10,646 × 10(-6) with an expanded uncertainty (k = 2) of 88 × 10(-6) were obtained, respectively. The absolute carbon isotope ratio of the VPDB standard was found to be 11,115 × 10(-6) with an expanded uncertainty (k = 2) of 27 × 10(-6), which is in excellent agreement with previously published values.

Accurate and stable equal-pressure measurements of water vapor transmission rate reaching the 10-6 g m-2 day-1 range

NASA Astrophysics Data System (ADS)

Nakano, Yoichiro; Yanase, Takashi; Nagahama, Taro; Yoshida, Hajime; Shimada, Toshihiro

2016-10-01

The water vapor transmission rate (WVTR) of a gas barrier coating is a critically important parameter for flexible organic device packaging, but its accurate measurement without mechanical stress to ultrathin films has been a significant challenge in instrumental analysis. At the current stage, no reliable results have been reported in the range of 10-6 g m-2 day-1 that is required for organic light emitting diodes (OLEDs). In this article, we describe a solution for this difficult, but important measurement, involving enhanced sensitivity by a cold trap, stabilized temperature system, pumped sealing and calibration by a standard conductance element.

40 CFR 265.146 - Use of a mechanism for financial assurance of both closure and post-closure care.

Code of Federal Regulations, 2013 CFR

2013-07-01

... assurance of both closure and post-closure care. 265.146 Section 265.146 Protection of Environment... Use of a mechanism for financial assurance of both closure and post-closure care. An owner or operator may satisfy the requirements for financial assurance for both closure and post-closure care for one or...

4. PART 1 OF 3 PART PANORAMA WITH NOS. CA265J5 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. PART 1 OF 3 PART PANORAMA WITH NOS. CA-265-J-5 AND CA-265-J-6 OF FIGUEROA STREET AND LOS ANGELES RIVER VIADUCTS. NOTE TUNNEL NO.1 NORTH PORTAL AT LEFT REAR. LOOKING 268°W. - Arroyo Seco Parkway, Figueroa Street Viaduct, Spanning Los Angeles River, Los Angeles, Los Angeles County, CA

41 CFR 102-34.265 - May we keep a Government-owned motor vehicle even though the standard permits replacement?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false May we keep a Government-owned motor vehicle even though the standard permits replacement? 102-34.265 Section 102-34.265 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION PERSONAL PROPERTY 34...

45 CFR 265.3 - What reports must the State file on a quarterly basis?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true What reports must the State file on a quarterly basis? 265.3 Section 265.3 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES DATA COLLECTION AND REPORTING...

40 CFR 265.1061 - Alternative standards for valves in gas/vapor service or in light liquid service: percentage of...

Code of Federal Regulations, 2010 CFR

2010-07-01

... gas/vapor service or in light liquid service: percentage of valves allowed to leak. 265.1061 Section... FACILITIES Air Emission Standards for Equipment Leaks § 265.1061 Alternative standards for valves in gas/vapor service or in light liquid service: percentage of valves allowed to leak. (a) An owner or operator...

40 CFR 265.1061 - Alternative standards for valves in gas/vapor service or in light liquid service: percentage of...

Code of Federal Regulations, 2011 CFR

2011-07-01

... gas/vapor service or in light liquid service: percentage of valves allowed to leak. 265.1061 Section... FACILITIES Air Emission Standards for Equipment Leaks § 265.1061 Alternative standards for valves in gas/vapor service or in light liquid service: percentage of valves allowed to leak. (a) An owner or operator...

40 CFR 265.1061 - Alternative standards for valves in gas/vapor service or in light liquid service: percentage of...

Code of Federal Regulations, 2012 CFR

2012-07-01

... gas/vapor service or in light liquid service: percentage of valves allowed to leak. 265.1061 Section... FACILITIES Air Emission Standards for Equipment Leaks § 265.1061 Alternative standards for valves in gas/vapor service or in light liquid service: percentage of valves allowed to leak. (a) An owner or operator...

40 CFR 265.1062 - Alternative standards for valves in gas/vapor service or in light liquid service: skip period...

Code of Federal Regulations, 2014 CFR

2014-07-01

... gas/vapor service or in light liquid service: skip period leak detection and repair. 265.1062 Section... FACILITIES Air Emission Standards for Equipment Leaks § 265.1062 Alternative standards for valves in gas/vapor service or in light liquid service: skip period leak detection and repair. (a) An owner or...

40 CFR 265.1062 - Alternative standards for valves in gas/vapor service or in light liquid service: skip period...

Code of Federal Regulations, 2011 CFR

2011-07-01

... gas/vapor service or in light liquid service: skip period leak detection and repair. 265.1062 Section... FACILITIES Air Emission Standards for Equipment Leaks § 265.1062 Alternative standards for valves in gas/vapor service or in light liquid service: skip period leak detection and repair. (a) An owner or...

40 CFR 265.1062 - Alternative standards for valves in gas/vapor service or in light liquid service: skip period...

Code of Federal Regulations, 2010 CFR

2010-07-01

... gas/vapor service or in light liquid service: skip period leak detection and repair. 265.1062 Section... FACILITIES Air Emission Standards for Equipment Leaks § 265.1062 Alternative standards for valves in gas/vapor service or in light liquid service: skip period leak detection and repair. (a) An owner or...

40 CFR 265.1062 - Alternative standards for valves in gas/vapor service or in light liquid service: skip period...

Code of Federal Regulations, 2013 CFR

2013-07-01

... gas/vapor service or in light liquid service: skip period leak detection and repair. 265.1062 Section... FACILITIES Air Emission Standards for Equipment Leaks § 265.1062 Alternative standards for valves in gas/vapor service or in light liquid service: skip period leak detection and repair. (a) An owner or...

40 CFR 265.1062 - Alternative standards for valves in gas/vapor service or in light liquid service: skip period...

Code of Federal Regulations, 2012 CFR

2012-07-01

... gas/vapor service or in light liquid service: skip period leak detection and repair. 265.1062 Section... FACILITIES Air Emission Standards for Equipment Leaks § 265.1062 Alternative standards for valves in gas/vapor service or in light liquid service: skip period leak detection and repair. (a) An owner or...

40 CFR 265.1061 - Alternative standards for valves in gas/vapor service or in light liquid service: percentage of...

Code of Federal Regulations, 2013 CFR

2013-07-01

... gas/vapor service or in light liquid service: percentage of valves allowed to leak. 265.1061 Section... FACILITIES Air Emission Standards for Equipment Leaks § 265.1061 Alternative standards for valves in gas/vapor service or in light liquid service: percentage of valves allowed to leak. (a) An owner or operator...

40 CFR 265.1061 - Alternative standards for valves in gas/vapor service or in light liquid service: percentage of...

Code of Federal Regulations, 2014 CFR

2014-07-01

... gas/vapor service or in light liquid service: percentage of valves allowed to leak. 265.1061 Section... FACILITIES Air Emission Standards for Equipment Leaks § 265.1061 Alternative standards for valves in gas/vapor service or in light liquid service: percentage of valves allowed to leak. (a) An owner or operator...

Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study.

PubMed

McCarthy, James S; Lotharius, Julie; Rückle, Thomas; Chalon, Stephan; Phillips, Margaret A; Elliott, Suzanne; Sekuloski, Silvana; Griffin, Paul; Ng, Caroline L; Fidock, David A; Marquart, Louise; Williams, Noelle S; Gobeau, Nathalie; Bebrevska, Lidiya; Rosario, Maria; Marsh, Kennan; Möhrle, Jörg J

2017-06-01

DSM265 is a novel antimalarial that inhibits plasmodial dihydroorotate dehydrogenase, an enzyme essential for pyrimidine biosynthesis. We investigated the safety, tolerability, and pharmacokinetics of DSM265, and tested its antimalarial activity. Healthy participants aged 18-55 years were enrolled in a two-part study: part 1, a single ascending dose (25-1200 mg), double-blind, randomised, placebo-controlled study, and part 2, an open-label, randomised, active-comparator controlled study, in which participants were inoculated with Plasmodium falciparum induced blood-stage malaria (IBSM) and treated with DSM265 (150 mg) or mefloquine (10 mg/kg). Primary endpoints were DSM265 safety, tolerability, and pharmacokinetics. Randomisation lists were created using a validated, automated system. Both parts were registered with the Australian New Zealand Clinical Trials Registry, number ACTRN12613000522718 (part 1) and number ACTRN12613000527763 (part 2). In part 1, 73 participants were enrolled between April 12, 2013, and July 14, 2015 (DSM265, n=55; placebo, n=18). In part 2, nine participants were enrolled between Sept 30 and Nov 25, 2013 (150 mg DSM265, n=7; 10 mg/kg mefloquine, n=2). In part 1, 117 adverse events were reported; no drug-related serious or severe events were reported. The most common drug-related adverse event was headache. The mean DSM265 peak plasma concentration (C max ) ranged between 1310 ng/mL and 34 800 ng/mL and was reached in a median time (t max ) between 1·5 h and 4 h, with a mean elimination half-life between 86 h and 118 h. In part 2, the log 10 parasite reduction ratio at 48 h in the DSM265 (150 mg) group was 1·55 (95% CI 1·42-1·67) and in the mefloquine (10 mg/kg) group was 2·34 (2·17-2·52), corresponding to a parasite clearance half-life of 9·4 h (8·7-10·2) and 6·2 h (5·7-6·7), respectively. The median minimum inhibitory concentration of DSM265 in blood was estimated as 1040 ng/mL (range 552-1500), resulting in a predicted single efficacious dose of 340 mg. Parasite clearance was significantly faster in participants who received mefloquine than in participants who received DSM265 (p<0·0001). The good safety profile, long elimination half-life, and antimalarial effect of DSM265 supports its development as a partner drug in a single-dose antimalarial combination treatment. Wellcome Trust, UK Department for International Development, Global Health Innovative Technology Fund, Bill & Melinda Gates Foundation. Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license. Published by Elsevier Ltd.. All rights reserved.

[Tricholoma equestre--animal toxicity study].

PubMed

Chodorowski, Zygmunt; Sznitowska, Małgorzata; Wiśniewski, Marek; Sein Anand, Jacek; Waldman, Wojciech; Ronikier, Anna

2004-01-01

Animal toxicity study of Tricholoma equestre mushrooms stored for 12 months at (-)20 degrees C was performed using 30 male BALB/c mice. Three groups of 5 mice each were given suspension of T. equestre powder in water, boiled aqueous extract and chloroform-methanol extract dissolved in Miglyol 812 by gavage for three consecutive days. Mice in control groups were given water, Miglyol 812 and p-phenylenediamine (CAS 106-50-3). Creatine kinase activity was determined in serum collected 72 hours after the final dose. Mean activity of serum creatine kinase in mice treated with T. equestre powder, aqueous extract, chloroform-methanol extract and Miglyol 812 were 157 +/- 93, 129 +/- 30, 96 +/- 38, 111 +/- 66 U/L respectively and did not differ significantly from mean activity in mice which were given water (107 +/- 38 U/L). Mean serum creatine kinase activity in p-phenylenediamine group (265 +/- 63 U/L) was significantly higher than in group treated with water (p<0.01). Extracts of Tricholoma equestre mushrooms stored for 12 months at (-)20 degrees C did not cause rhabdomyolysis in male BALB/c mice.

Associations between informal care, disease, and risk factors: A Spanish country-wide population-based study.

PubMed

González-de Paz, Luís; Real, Jordi; Borrás-Santos, Alicia; Martínez-Sánchez, José M; Rodrigo-Baños, Virginia; Dolores Navarro-Rubio, María

2016-05-01

This population-based study using 2011-2012 Spanish National Health Survey data aimed to measure the impact of disease, health-related habits, and risk factors associated with informal caregiving. We included and matched self-reported informal caregivers [ICs] with controls (1:4) from the same survey. For each outcome, we analyzed associations between ICs and controls using linear regression or logistic regression models. ICs had 3.4 per cent more depression (OR: 1.33, 95 per cent confidence intervals [CI]:1.06, 1.68). ICs had lower social support (95 per cent CI: 1.64, 3.28), they did more housework alone (OR:3.6, 95 per cent CI:2.65, 4.89), and had greater stress (95 per cent CI:0.13, 0.83). Women ICs caring alone had more anxiety than other groups. We found no statistical association between caregivers and worse health-related habits or increased risk factors (less physical activity, smoking, drinking, and cholesterol). Our results provide evidence that health-care professionals and organizations should recognize the importance of caring for those who care.

Ultrasonic effects on titanium tanning of leather.

PubMed

Peng, Biyu; Shi, Bi; Sun, Danhong; Chen, Yaowen; Shelly, Dennis C

2007-03-01

The effects of ultrasound on titanium tanning of leather were investigated. Either 20 or 40 kHz ultrasound was applied to the titanium tanning of pigskins. Five different treatment conditions were carried out and the effects were examined, such as leather shrinkage temperature (T(s)), titanium content and titanium distribution in the leather. Overall heat loading was carefully controlled. Results showed that 20 kHz ultrasound effectively improves titanium agent penetration into the hide and increases the leather's shrinkage temperature. Doubling the frequency to 40 kHz produced negligible enhancements. An impressive 105.6 degrees C T(s) was achieved using 20 kHz ultrasound pretreatment of the tanning liquor followed by 20 kHz ultrasound in the tanning mixture (liquor plus pigskins) in a special salt-free medium. Finally, using a unique ultrasonic tanning drum with 26.5 kHz ultrasound, the T(s) reached a record level of 106.5 degrees C, a value not achieved in conventional (no ultrasound) titanium tanning. The ultrasonic effects on titanium tanning of leather are judged to make a superior mineral tanned leather.

Microencapsulation of Islets of Langerhans via selective withdrawal to achieve immunoisolation

NASA Astrophysics Data System (ADS)

Wyman, Jason; Dillmore, Shannon; Murphy, William; Garfinkel, Marc; Mrksich, Milan; Nagel, Sidney

2004-03-01

Cohen phet al. [1] described how the selective-withdrawal geometry may be used to microencapsulate particles in thin coats whose thickness is independent of the size of the encapsulated particle. We have applied a modified version of this geometry to the microencapsulation of Islets of Langerhans for the purpose of immunoisolation. The Islets are initially placed in a polymer-containing aqueous solution which is then drawn up into a selective-withdrawal spout. As that spout breaks up, it leaves the Islets coated with the polymer solution. These coats are then photo-crosslinked leaving the Islets encapsulated in a hydrogel coating. This coating provides a semi-permeable membrane which allows for the diffusion of small molecules such as nutrients, glucose, and insulin, but which excludes larger proteins such as antibodies. If one can successfully microencapsulate 10^6 islets in uniform coats such as these, then one may transplant Islets without immuno-suppression as a treatment for Type-I Diabetes. We will discuss preliminary phin vitro results. [1] I. Cohen, H. Li, J. L. Hougland, M. Mrksich, and S. R. Nagel Science 292, 265-267 (2001).

Chemical Dissolution of Simulant FCA Cladding and Plates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Daniel, G.; Pierce, R.; O'Rourke, P.

The Savannah River Site (SRS) has received some fast critical assembly (FCA) fuel from the Japan Atomic Energy Agency (JAEA) for disposition. Among the JAEA FCA fuel are approximately 7090 rectangular Stainless Steel clad fuel elements. Each element has an internal Pu-10.6Al alloy metal wafer. The thickness of each element is either 1/16 inch or 1/32 inch. The dimensions of each element ranges from 2 inches x 1 inch to 2 inches x 4 inches. This report discusses the potential chemical dissolution of the FCA clad material or stainless steel. This technology uses nitric acid-potassium fluoride (HNO 3-KF) flowsheets ofmore » H-Canyon to dissolve the FCA elements from a rack of materials. Historically, dissolution flowsheets have aimed to maximize Pu dissolution rates while minimizing stainless steel dissolution (corrosion) rates. Because the FCA cladding is made of stainless steel, this work sought to accelerate stainless steel dissolution.« less

[Study on the determination of 14 inorganic elements in coffee by inductively coupled plasma mass spectrometry].

PubMed

Nie, Xi-Du; Fu, Liang

2013-07-01

Samples of coffee were digested by microwave digestion, and inorganic elements amounts of Na, Mg, P, Ca, Cr, Mn, Fe, Co, Cu, Zn, As, Se, Mo and Pb in sample solutions were determined by inductively coupled plasma mass spectrometry (ICP-MS). HNO3 + H2O2 was used to achieve the complete decomposition of the organic matrix in a closed-vessel microwave oven. The working parameters of the instrument were optimized. The results showed that the relative standard deviation (RSD) was less than 3.84% for all the elements, and the recovery was found to be 92.00% -106.52% by adding standard recovery experiment. This method was simple, sensitive and precise and can perform simultaneous multi-elements determination of coffee, which could satisfy the sample examination request and provide scientific rationale for determining inorganic elements of coffee.

6. PART 3 OF 3 PART PANORAMA WITH NOS. CA265J4 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. PART 3 OF 3 PART PANORAMA WITH NOS. CA-265-J-4 AND CA-265-J-5 OF FIGUEROA STREET AND LOS ANGELES RIVER VIADUCTS. NOTE ARROYO SECO CHANNEL ENTERING LOS ANGELES RIVER UNDER RAILROAD TRESTLE AT RIGHT. LOOKING 268°W. - Arroyo Seco Parkway, Figueroa Street Viaduct, Spanning Los Angeles River, Los Angeles, Los Angeles County, CA

45 CFR 265.8 - Under what circumstances will we take action to impose a reporting penalty for failure to submit...

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true Under what circumstances will we take action to impose a reporting penalty for failure to submit quarterly and annual reports? 265.8 Section 265.8 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES,...

Thermodynamic stability of boron: the role of defects and zero point motion.

PubMed

van Setten, Michiel J; Uijttewaal, Matthé A; de Wijs, Gilles A; de Groot, Robert A

2007-03-07

Its low weight, high melting point, and large degree of hardness make elemental boron a technologically interesting material. The large number of allotropes, mostly containing over a hundred atoms in the unit cell, and their difficult characterization challenge both experimentalists and theoreticians. Even the ground state of this element is still under discussion. For over 30 years, scientists have attempted to determine the relative stability of alpha- and beta-rhombohedral boron. We use density functional calculations in the generalized gradient approximation to study a broad range of possible beta-rhombohedral structures containing interstitial atoms and partially occupied sites within a 105 atoms framework. The two most stable structures are practically degenerate in energy and semiconducting. One contains the experimental 320 atoms in the hexagonal unit cell, and the other contains 106 atoms in the triclinic unit cell. When populated with the experimental 320 electrons, the 106 atom structure exhibits a band gap of 1.4 eV and an in-gap hole trap at 0.35 eV above the valence band, consistent with known experiments. The total energy of these two structures is 23 meV/B lower than the original 105 atom framework, but it is still 1 meV/B above the alpha phase. Adding zero point energies finally makes the beta phase the ground state of elemental boron by 3 meV/B. At finite temperatures, the difference becomes even larger.

Is RNASEL:p.Glu265* a modifier of early-onset breast cancer risk for carriers of high-risk mutations?

PubMed

Nguyen-Dumont, Tú; Teo, Zhi L; Hammet, Fleur; Roberge, Alexis; Mahmoodi, Maryam; Tsimiklis, Helen; Park, Daniel J; Pope, Bernard J; Lonie, Andrew; Kapuscinski, Miroslav K; Mahmood, Khalid; Goldgar, David E; Giles, Graham G; Winship, Ingrid; Hopper, John L; Southey, Melissa C

2018-02-08

Breast cancer risk for BRCA1 and BRCA2 pathogenic mutation carriers is modified by risk factors that cluster in families, including genetic modifiers of risk. We considered genetic modifiers of risk for carriers of high-risk mutations in other breast cancer susceptibility genes. In a family known to carry the high-risk mutation PALB2:c.3113G>A (p.Trp1038*), whole-exome sequencing was performed on germline DNA from four affected women, three of whom were mutation carriers. RNASEL:p.Glu265* was identified in one of the PALB2 carriers who had two primary invasive breast cancer diagnoses before 50 years. Gene-panel testing of BRCA1, BRCA2, PALB2 and RNASEL in the Australian Breast Cancer Family Registry identified five carriers of RNASEL:p.Glu265* in 591 early onset breast cancer cases. Three of the five women (60%) carrying RNASEL:p.Glu265* also carried a pathogenic mutation in a breast cancer susceptibility gene compared with 30 carriers of pathogenic mutations in the 586 non-carriers of RNASEL:p.Glu265* (5%) (p < 0.002). Taqman genotyping demonstrated that the allele frequency of RNASEL:p.Glu265* was similar in affected and unaffected Australian women, consistent with other populations. Our study suggests that RNASEL:p.Glu265* may be a genetic modifier of risk for early-onset breast cancer predisposition in carriers of high-risk mutations. Much larger case-case and case-control studies are warranted to test the association observed in this report.

Development and validation of an HPLC method for the determination of ten sulfonamide residues in milk according to 2002/657/EC.

PubMed

Tolika, Evanthia P; Samanidou, Victoria F; Papadoyannis, Ioannis N

2011-07-01

A HPLC method with diode-array detection, at 265 nm, was developed and validated for the determination of ten sulfonamides (SAs): sulfadiazine (SDZ), sulfathiazine (STZ), sulfamethoxine (SMTH), sulfamethizole (SMZ), sulfamethoxypyridazine (SMPZ), sulfamonomethoxine (SMMX), sulfamethoxazole (SMXZ), sulfisoxazole (SIX), sulfadimethoxine (SDMX), and sulfaquinoxaline (SQX) in milk. A mixture of ethyl acetate, n-hexane, and isopropanol was used for the extraction of target analytes from milk. The mobile phase, a mixture of 0.1% v/v formic acid, CH(3) CN, and CH(3) OH was delivered to the analytical column under a gradient program. The procedure was validated according to the European Union regulation 2002/657/EC in terms of selectivity, stability, decision limit, detection capability, accuracy, and precision. Mean recoveries of sulfonamides from milk samples spiked at three concentration levels (0.5×MRL, 1×MRL, and 1.5×MRL) (MRL, maximum residue level) were 93.9-115.9% for SDZ, 97.8-102.9% for STZ, 94.6-107.0% for SMTH, 98.3-111.5% for SMZ, 95.3-108.4% for SMPZ, 97.9-106.0% for SMMX, 97.6-111.3% for SMXZ, 94.3-104.6% for SIX, 96.4-109.1% for SDMX, and 98.2-111.2% for SQX. All RSD values were lower than 8.8%. The decision limits CCa calculated by spiking 20 blank milk samples at MRL (100 μg/kg) ranged from 101.61 to 106.84 μg/kg, whereas the detection capability CCb ranged from 105.64 to 119.01 μg/kg. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Podocyte Number in Children and Adults: Associations with Glomerular Size and Numbers of Other Glomerular Resident Cells

PubMed Central

Puelles, Victor G.; Douglas-Denton, Rebecca N.; Cullen-McEwen, Luise A.; Li, Jinhua; Hughson, Michael D.; Hoy, Wendy E.; Kerr, Peter G.

2015-01-01

Increases in glomerular size occur with normal body growth and in many pathologic conditions. In this study, we determined associations between glomerular size and numbers of glomerular resident cells, with a particular focus on podocytes. Kidneys from 16 male Caucasian-Americans without overt renal disease, including 4 children (≤3 years old) to define baseline values of early life and 12 adults (≥18 years old), were collected at autopsy in Jackson, Mississippi. We used a combination of immunohistochemistry, confocal microscopy, and design-based stereology to estimate individual glomerular volume (IGV) and numbers of podocytes, nonepithelial cells (NECs; tuft cells other than podocytes), and parietal epithelial cells (PECs). Podocyte density was calculated. Data are reported as medians and interquartile ranges (IQRs). Glomeruli from children were small and contained 452 podocytes (IQR=335–502), 389 NECs (IQR=265–498), and 146 PECs (IQR=111–206). Adult glomeruli contained significantly more cells than glomeruli from children, including 558 podocytes (IQR=431–746; P<0.01), 1383 NECs (IQR=998–2042; P<0.001), and 367 PECs (IQR=309–673; P<0.001). However, large adult glomeruli showed markedly lower podocyte density (183 podocytes per 106 µm3) than small glomeruli from adults and children (932 podocytes per 106 µm3; P<0.001). In conclusion, large adult glomeruli contained more podocytes than small glomeruli from children and adults, raising questions about the origin of these podocytes. The increased number of podocytes in large glomeruli does not match the increase in glomerular size observed in adults, resulting in relative podocyte depletion. This may render hypertrophic glomeruli susceptible to pathology. PMID:25568174

Factorizable amplitude in B0→π+π-

NASA Astrophysics Data System (ADS)

Luo, Zumin; Rosner, Jonathan L.

2003-10-01

Using the measured spectrum shape for B→πlν, the rate for B+→π+π0, information on the Cabibbo-Kobayashi-Maskawa matrix element |Vub|, and theoretical inputs from factorization and lattice gauge theory, we obtain an improved estimate of the “tree” contribution to B0→π+π-. We find the branching ratio B(B0→π+π-)|tree=(5.25+1.67-0.50)×10-6 to be compared with the experimental value B(B0→π+π-)=(4.55±0.44)×10-6. The fit implies |Vub|=(3.62±0.34)×10-3. Implications for tree-penguin interference in B0→π+π- and for other charmless B decays are discussed.

A table of semiempirical gf values. Part 2. Wavelengths: 272. 3395 nm to 599. 3892 nm

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kurucz, R.L.; Peytremann, E.

1975-02-14

The gf values for 265,587 atomic lines selectedfrom the line data used to calculate line blanketed model atmospheres are tabulated. These data are especially useful for line identification and spectral synthesis in solar and stellar spectra. The gf values are calculated semiempirically by using scaled Thomas--Fermi--Dirac radial wave functions and eigenvectors found through least-squares fits to observed energy levels. Included in the calculation are the first five or six stages of ionization for sequences up through nickel. Published gf values are included for elements heavier than nickel. The tabulation is restricted to lines with wavelengths less than 10 micrometers. (auth)

Aircraft wing structural design optimization based on automated finite element modelling and ground structure approach

NASA Astrophysics Data System (ADS)

Yang, Weizhu; Yue, Zhufeng; Li, Lei; Wang, Peiyan

2016-01-01

An optimization procedure combining an automated finite element modelling (AFEM) technique with a ground structure approach (GSA) is proposed for structural layout and sizing design of aircraft wings. The AFEM technique, based on CATIA VBA scripting and PCL programming, is used to generate models automatically considering the arrangement of inner systems. GSA is used for local structural topology optimization. The design procedure is applied to a high-aspect-ratio wing. The arrangement of the integral fuel tank, landing gear and control surfaces is considered. For the landing gear region, a non-conventional initial structural layout is adopted. The positions of components, the number of ribs and local topology in the wing box and landing gear region are optimized to obtain a minimum structural weight. Constraints include tank volume, strength, buckling and aeroelastic parameters. The results show that the combined approach leads to a greater weight saving, i.e. 26.5%, compared with three additional optimizations based on individual design approaches.

Evaluation for the ecological quality status of coastal waters in East China Sea using fuzzy integrated assessment method.

PubMed

Wu, H Y; Chen, K L; Chen, Z H; Chen, Q H; Qiu, Y P; Wu, J C; Zhang, J F

2012-03-01

This research presented an evaluation for the ecological quality status (EcoQS) of three semi-enclosed coastal areas using fuzzy integrated assessment method (FIAM). With this method, the hierarchy structure was clarified by an index system of 11 indicators selected from biotic elements and physicochemical elements, and the weight vector of index system was calculated with Delphi-Analytic Hierarchy Process (AHP) procedure. Then, the FIAM was used to achieve an EcoQS assessment. As a result of assessment, most of the sampling stations demonstrated a clear gradient in EcoQS, ranging from high to poor status. Among the four statuses, high and good, owning a ratio of 55.9% and 26.5%, respectively, were two dominant statuses for three bays, especially for Sansha Bay and Luoyuan Bay. The assessment results were found consistent with the pressure information and parameters obtained at most stations. In addition, the sources of uncertainty in classification of EcoQS were also discussed. Copyright © 2011 Elsevier Ltd. All rights reserved.

Boron Abundances Across the "Li-Be Dip" in the Hyades Cluster

NASA Astrophysics Data System (ADS)

Boesgaard, Ann Merchant; Lum, Michael G.; Deliyannis, Constantine P.; King, Jeremy R.; Pinsonneault, Marc H.

2015-08-01

Dramatic deficiencies of Li in the mid-F dwarf stars of the Hyades cluster were discovered by Boesgaard and Tripicco in 1986. Using high-resolution, high signal-to-noise spectra from the Keck 10-m telescope, Boesgaard and King discovered the corresponding, but smaller, deficiencies in Be in the same narrow temperature region in the Hyades. With the Space Telescope Imaging Spectrograph on HST we investigate B abundances in the Hyades F stars to look for a potential B dip. We use the resonance line of B I at 2497 A. These three elements are destroyed inside stars at increasingly hotter temperatures: 2.5 x 10$^6$, 3.5 x 10$^6$, and 5 x 10$^6$ K for Li, Be, B respectively. Consequently, these elements survive to increasingly greater depths in a star and their surface abundances act as a report on the depth and thoroughness of mixing in the star. We have used updated photometry from Hipparcos to find stellar parameters for the Hyades stars and have redetermined Li abundances (or upper limits) for 79 Hyades dwarfs, Be for 34 stars, and B in five stars. We find evidence for a small dip in the B abundance across the Li-Be dip. We have compared our nLTE B abundances for the three high B stars on either side of the Li-Be dip with those found by Duncan for the Hyades giants. This confirms the factor of ten decline in the B abundance in the Hyades giants as predicted by dilution due to the deepening of the surface convection zone.

A triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor (DSM421) with improved drug-like properties for treatment and prevention of malaria

PubMed Central

Phillips, Margaret A.; White, Karen L.; Kokkonda, Sreekanth; Deng, Xiaoyi; White, John; Mazouni, Farah El; Marsh, Kennan; Tomchick, Diana R.; Manjalanagara, Krishne; Rudra, Kakali Rani; Wirjanata, Grennady; Noviyanti, Rintis; Price, Ric N; Marfurt, Jutta; Shackleford, David M.; Chiu, Francis C.K.; Campbell, Michael; Jimenez-Diaz, Maria Belen; Bazaga, Santiago Ferrer; Angulo-Barturen, Iñigo; Martinez, Maria Santos; Lafuente-Monasterio, Maria; Kaminsky, Werner; Silue, Kigbafori; Zeeman, Anne-Marie; Kocken, Clemens; Leroy, Didier; Blasco, Benjamin; Rossignol, Emilie; Rueckle, Thomas; Matthews, Dave; Burrows, Jeremy N.; Waterson, David; Palmer, Michael J.; Rathod, Pradipsinh K.; Charman, Susan A.

2016-01-01

The emergence of drug resistant malaria parasites continues to hamper efforts to control this lethal disease. Dihydroorotate dehydrogenase has recently been validated as a new target for the treatment of malaria and a selective inhibitor (DSM265) of the Plasmodium enzyme is currently in clinical development. With the goal of identifying a backup compound to DSM265, we explored replacement of the SF5-aniline moiety of DSM265 with a series of CF3-pyridinyls, while maintaining the core triazolopyrimidine scaffold. This effort led to the identification of DSM421, which has improved solubility, lower intrinsic clearance and increased plasma exposure after oral dosing compared to DSM265, while maintaining a long predicted human half-life. Its improved physical and chemical properties will allow it to be formulated more readily than DSM265. DSM421 showed excellent efficacy in the SCID mouse model of P. falciparum malaria that supports the prediction of a low human dose (<200 mg). Importantly DSM421 showed equal activity against both P. falciparum and P. vivax field isolates, while DSM265 was more active on P. falciparum. DSM421 has the potential to be developed as a single dose cure or once-weekly chemopreventative for both P. falciparum and P. vivax malaria leading to its advancement as a preclinical development candidate. PMID:27641613

Geochemistry of the Serifos calc-alkaline granodiorite pluton, Greece: constraining the crust and mantle contributions to I-type granitoids

NASA Astrophysics Data System (ADS)

Stouraiti, C.; Baziotis, I.; Asimow, P. D.; Downes, H.

2017-11-01

The Late Miocene (11.6-9.5 Ma) granitoid intrusion on the island of Serifos (Western Cyclades, Aegean Sea) is composed of syn- to post-tectonic granodiorite with quartz monzodiorite enclaves, cut by dacitic and aplitic dikes. The granitoid, a typical I-type metaluminous calcic amphibole-bearing calc-alkaline pluton, intruded the Cycladic Blueschists during thinning of the Aegean plate. Combining field, textural, geochemical and new Sr-Nd-O isotope data presented in this paper, we postulate that the Serifos intrusion is a single-zoned pluton. The central facies has initial 87Sr/86Sr = 0.70906 to 0.7106, ɛNd(t) = - 5.9 to - 7.5 and δ18Οqtz = + 10 to + 10.6‰, whereas the marginal zone (or border facies) has higher initial 87Sr/86Sr = 0.711 to 0.7112, lower ɛ Nd(t) = - 7.3 to - 8.3, and higher δ18Οqtz = + 10.6 to + 11.9‰. The small range in initial Sr and Nd isotopic values throughout the pluton is paired with a remarkable uniformity in trace element patterns, despite a large range in silica contents (58.8 to 72 wt% SiO2). Assimilation of a crustally derived partial melt into the mafic parental magma would progressively add incompatible trace elements and SiO2 to the evolving mafic starting liquid, but the opposite trend, of trace element depletion during magma evolution, is observed in the Serifos granodiorites. Thermodynamic modeling of whole-rock compositions during simple fractional crystallization (FC) or assimilation-fractional crystallization (AFC) processes of major rock-forming minerals—at a variety of pressure, oxidation state, and water activity conditions—fails to reproduce simultaneously the major element and trace element variations among the Serifos granitoids, implying a critical role for minor phases in controlling trace element fractionation. Both saturation of accessory phases such as allanite and titanite (at SiO2 ≥ 71 wt%)(to satisfy trace element constraints) and assimilation of partial melts from a metasedimentary component (to match isotopic data) must have accompanied fractional crystallization of the major phases.

40 CFR 265.404 - Closure.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., Physical, and Biological Treatment § 265.404 Closure. At closure, all hazardous waste and hazardous waste residues must be removed from treatment processes or equipment, discharge control equipment, and discharge...

40 CFR 265.404 - Closure.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., Physical, and Biological Treatment § 265.404 Closure. At closure, all hazardous waste and hazardous waste residues must be removed from treatment processes or equipment, discharge control equipment, and discharge...

40 CFR 265.404 - Closure.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., Physical, and Biological Treatment § 265.404 Closure. At closure, all hazardous waste and hazardous waste residues must be removed from treatment processes or equipment, discharge control equipment, and discharge...