7 CFR 1150.278 - Confidential treatment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 9 2010-01-01 2009-01-01 true Confidential treatment. 1150.278 Section 1150.278 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... of Milk Producer Organizations § 1150.278 Confidential treatment. All documents and other information...

30 CFR 27.8 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false [Reserved] 27.8 Section 27.8 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS METHANE-MONITORING SYSTEMS General Provisions § 27.8 [Reserved] ...

JPRS Report Science and Technology, Japan: Atomic Energy Society 1989 Annual Meeting.

DTIC Science & Technology

1989-10-13

Control Rod Hole in VHTRC-1 Core [F, Akino, T, Yamane, et al.] ,,, 5 Measurement of MEU [Medium Enriched Uranium ] Fuel Element Characteristics in...K. Yoshida, K. Kobayashi, I. Kimura , C. Yamanaka, and S. Nakai, Laser Laboratory,, Osaka University. Nuclear Reactor Laboratory, Kyoto University...1 core loaded with 278 fuel rods (4 percent enriched uranium ). The PNS target was placed at the back center of the 1/2 assembly on the fixed side

40 CFR 52.278 - Oxides of nitrogen control.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Oxides of nitrogen control. 52.278 Section 52.278 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.278 Oxides of nitrogen control...

9 CFR 2.78 - Health certification and identification.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Health certification and identification. 2.78 Section 2.78 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Records § 2.78 Health certification and identification...

9 CFR 2.78 - Health certification and identification.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Health certification and identification. 2.78 Section 2.78 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Records § 2.78 Health certification and identification...

9 CFR 2.78 - Health certification and identification.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Health certification and identification. 2.78 Section 2.78 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Records § 2.78 Health certification and identification...

9 CFR 2.78 - Health certification and identification.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Health certification and identification. 2.78 Section 2.78 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Records § 2.78 Health certification and identification...

9 CFR 2.78 - Health certification and identification.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Health certification and identification. 2.78 Section 2.78 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Records § 2.78 Health certification and identification...

7 CFR 278.2 - Participation of retail food stores.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 4 2013-01-01 2013-01-01 false Participation of retail food stores. 278.2 Section 278..., DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM PARTICIPATION OF RETAIL FOOD STORES, WHOLESALE FOOD CONCERNS AND INSURED FINANCIAL INSTITUTIONS § 278.2 Participation of retail food stores. (a...

7 CFR 278.2 - Participation of retail food stores.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 4 2012-01-01 2012-01-01 false Participation of retail food stores. 278.2 Section 278..., DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM PARTICIPATION OF RETAIL FOOD STORES, WHOLESALE FOOD CONCERNS AND INSURED FINANCIAL INSTITUTIONS § 278.2 Participation of retail food stores. (a...

27 CFR 19.278 - Identification of structures, areas, apparatus, and equipment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... structures, areas, apparatus, and equipment. 19.278 Section 19.278 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Construction, Equipment and Security § 19.278 Identification of structures, areas, apparatus, and equipment. (a...

Applied Mathematical Modules for Use in a Linear Algebra Service Course

DTIC Science & Technology

1990-05-01

H . (1977). Elements of ohysical chemistry. Reading, MA: Addison-Wesley. Rorres , C . & Anton , H . (1984). Applications...k t)r+ v𔃽 A142"+ c -- + C Vt +1 t+ C c tKc cos t 2= 113 123 313 32-3 51 2 V - cu-14sin r t) 232 _E _ VL3 h 3kx3 Cl t + c1 _3 t c + 3 =11-3 12 3 31 6... H " O H H H o 0 0 H H H H H H Ao, //o\\ H HH H

31 CFR 27.8 - Judicial review.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Judicial review. 27.8 Section 27.8... OF DEPARTMENT OF THE TREASURY NAMES, SYMBOLS, ETC. § 27.8 Judicial review. A final Notice of Assessment issued under this party may be subject to judicial review pursuant to 5 U.S.C. 701 et seq. ...

18 CFR 2.78 - Utilization and conservation of natural resources-natural gas.

Code of Federal Regulations, 2011 CFR

2011-04-01

... conservation of natural resources-natural gas. 2.78 Section 2.78 Conservation of Power and Water Resources... INTERPRETATIONS Statements of General Policy and Interpretations Under the Natural Gas Act § 2.78 Utilization and conservation of natural resources—natural gas. (a)(1) The national interests in the development and utilization...

Prospects of A and Z identification experiments at LBNL

NASA Astrophysics Data System (ADS)

Gates, Jacklyn M.

2016-12-01

The identification of six new elements within the last 15 years and with proton numbers, Z = 113-118 has transformed the heavy element field. However, one key piece of information on these nuclei remains unmeasured: their proton and mass numbers, A. At Lawrence Berkeley National Laboratory, the heavy element group has undertaken a program to study these new elements to perform experiments aimed at measuring the Z and A.Here, an overview of recent experiments aimed towards identifying the Z of SHE, and the prospects for Z and A identification experiments at LBNL are presented.

Theoretical Predictions of Cross-Sections of the Super-Heavy Elements

NASA Astrophysics Data System (ADS)

Bouriquet, B.; Kosenko, G.; Abe, Y.

The evaluation of the residue cross-sections of reactionssynthesising superheavy elements has been achieved by the combination of the two-step model for fusion and the evaporation code (KEWPIE) for survival probability. The theoretical scheme of those calculations is presented, and some encouraging results are given, together with some difficulties. With this approach, the measured excitation functions of the 1n reactions producing elements with Z=108, 110, 111 and 112 are well reproduced. Thus, the model has been used to predict the cross-sections of the reactions leading to the formation of the elements with Z=113 and Z=114.

25 CFR 1000.278 - Does this coverage extend to subcontractors of self-governance AFAs?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Does this coverage extend to subcontractors of self-governance AFAs? 1000.278 Section 1000.278 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... INDIAN SELF-DETERMINATION AND EDUCATION ACT Federal Tort Claims § 1000.278 Does this coverage extend to...

Tissue Localization of Lymphocystis Disease Virus (LCDV) Receptor-27.8 kDa and Its Expression Kinetics Induced by the Viral Infection in Turbot (Scophthalmus maximus)

PubMed Central

Sheng, Xiuzhen; Wu, Ronghua; Tang, Xiaoqian; Xing, Jing; Zhan, Wenbin

2015-01-01

The 27.8 kDa membrane protein expressed in flounder (Paralichthys olivaceus) gill cells was proved to be a receptor mediating lymphocystis disease virus (LCDV) infection. In this study, SDS-PAGE and Western blotting demonstrated that 27.8 kDa receptor (27.8R) was shared by flounder and turbot (Scophthalmus maximus). Indirect immunofluorescence assay (IIFA) and immunohistochemistry showed that 27.8R was widely expressed in tested tissues of healthy turbot. The indirect enzyme-linked immunosorbent assay indicated that 27.8R expression was relatively higher in stomach, gill, heart, and intestine, followed by skin, head kidney, spleen, blood cells, kidney and liver, and lower in ovary and brain in healthy turbot, and it was significantly up-regulated after LCDV infection. Meanwhile, real-time quantitative PCR demonstrated that LCDV was detected in heart, peripheral blood cells, and head kidney at 3 h post infection (p.i.), and then in other tested tissues at 12 h p.i. LCDV copies increased in a time-dependent manner, and were generally higher in the tissues with higher 27.8R expression. Additionally, IIFA showed that 27.8R and LCDV were detected at 3 h p.i. in some leukocytes. These results suggested that 27.8R also served as a receptor in turbot, and LCDV can infect some leukocytes which might result in LCDV spreading to different tissues in turbot. PMID:26556346

Tissue Localization of Lymphocystis Disease Virus (LCDV) Receptor-27.8 kDa and Its Expression Kinetics Induced by the Viral Infection in Turbot (Scophthalmus maximus).

PubMed

Sheng, Xiuzhen; Wu, Ronghua; Tang, Xiaoqian; Xing, Jing; Zhan, Wenbin

2015-11-05

The 27.8 kDa membrane protein expressed in flounder (Paralichthys olivaceus) gill cells was proved to be a receptor mediating lymphocystis disease virus (LCDV) infection. In this study, SDS-PAGE and Western blotting demonstrated that 27.8 kDa receptor (27.8R) was shared by flounder and turbot (Scophthalmus maximus). Indirect immunofluorescence assay (IIFA) and immunohistochemistry showed that 27.8R was widely expressed in tested tissues of healthy turbot. The indirect enzyme-linked immunosorbent assay indicated that 27.8R expression was relatively higher in stomach, gill, heart, and intestine, followed by skin, head kidney, spleen, blood cells, kidney and liver, and lower in ovary and brain in healthy turbot, and it was significantly up-regulated after LCDV infection. Meanwhile, real-time quantitative PCR demonstrated that LCDV was detected in heart, peripheral blood cells, and head kidney at 3 h post infection (p.i.), and then in other tested tissues at 12 h p.i. LCDV copies increased in a time-dependent manner, and were generally higher in the tissues with higher 27.8R expression. Additionally, IIFA showed that 27.8R and LCDV were detected at 3 h p.i. in some leukocytes. These results suggested that 27.8R also served as a receptor in turbot, and LCDV can infect some leukocytes which might result in LCDV spreading to different tissues in turbot.

Molecular pathways underlying inhibitory effect of antimicrobial peptide Nal-P-113 on bacteria biofilms formation of Porphyromonas gingivalis W83 by DNA microarray.

PubMed

Wang, Hong-Yan; Lin, Li; Tan, Li-Si; Yu, Hui-Yuan; Cheng, Jya-Wei; Pan, Ya-Ping

2017-02-17

Wound-related infection remains a major challenge for health professionals. One disadvantage in conventional antibiotics is their inability to penetrate biofilms, the main protective strategy for bacteria to evade irradiation. Previously, we have shown that synthetic antimicrobial peptides could inhibit bacterial biofilms formation. In this study, we first delineated how Nal-P-113, a novel antimicrobial peptide, exerted its inhibitory effects on Porphyromonas gingivalis W83 biofilms formation at a low concentration. Secondly, we performed gene expression profiling and validated that Nal-P-113 at a low dose significantly down-regulated genes related to mobile and extrachromosomal element functions, transport and binding proteins in Porphyromonas gingivalis W83. These findings suggest that Nal-P-113 at low dose is sufficient to inhibit the formation of biofilms although Porphyromonas gingivalis W83 may maintain its survival in the oral cavity. The newly discovered molecular pathways may add the knowledge of developing a new strategy to target bacterial infections in combination with current first-line treatment in periodontitis.

7 CFR 271.8 - Information collection/recordkeeping-OMB assigned control numbers.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) 0584-0124 273.11 (a), (b), (c), (d), (e), (f), (h) 0584-0064 273.11 (g) 0584-0334 273.11 (i) (1)-(4... 273.18 (i) 0584-0053 273.21 (a), (c), (e), (f), (g), (h), (i), (j), (m), (p), (q) 0584-0064 274.1 (c...), (h) 0584-0083 278.1 (a), (b), (l) 0584-0008 278.1 (e), (f) 0584-0064 278.4 (b), (c) 0584-0085 278.5...

Heavy metal determinations in algae, mussels and clams. Their possible employment for assessing the sea water quality criteria

NASA Astrophysics Data System (ADS)

Locatelli, C.

2003-05-01

An empirical criterion for a possible classification of sea water quality is proposed. It is based on the knowledge of metal content in algae (Ulva Rigida) mussels (Mytilus Galloprovincialis) and clams (Tapes Philippinarum), three species present in marine ecosystems. The elements considered are Hg, Cu, Pb, Cd, Zn, Ni and Cr. The anatytical technique employed is Atomic Absorption Spectroscopy (AAS). The analytical procedure has been verified on three standard reference materials : Sea Water BCR-CRM 403, Ulva Lactuca BCR-CRM 279 and Mussel Tissue BCR-CRM 278. For all the elements, in addition to detection limits, accuracy and precision are given : the former, expressed as retative error (e). and the latter, expressed as relative standard deviation (sr), were in all cases lower than 6%.

STS-92 Mission Specialist Chiao drives the M-113

NASA Technical Reports Server (NTRS)

2000-01-01

With other crew members in the back, STS-92 Mission Specialist Leroy Chiao races the M-113 along the track through the scrub. Driving the M-113 is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

CMV-promoter driven codon-optimized expression alters the assembly type and morphology of a reconstituted HERV-K(HML-2).

PubMed

Hohn, Oliver; Hanke, Kirsten; Lausch, Veronika; Zimmermann, Anja; Mostafa, Saeed; Bannert, Norbert

2014-11-11

The HERV-K(HML-2) family contains the most recently integrated and best preserved endogenized proviral sequences in the human genome. All known elements have nevertheless been subjected to mutations or deletions that render expressed particles non-infectious. Moreover, these post-insertional mutations hamper the analysis of the general biological properties of this ancient virus family. The expression of consensus sequences and sequences of elements with reverted post-insertional mutations has therefore been very instrumental in overcoming this limitation. We investigated the particle morphology of a recently reconstituted HERV-K113 element termed oriHERV-K113 using thin-section electron microscopy (EM) and could demonstrate that strong overexpression by substitution of the 5'LTR for a CMV promoter and partial codon optimization altered the virus assembly type and morphology. This included a conversion from the regular C-type to an A-type morphology with a mass of cytoplasmic immature cores tethered to the cell membrane and the membranes of vesicles. Overexpression permitted the release and maturation of virions but reduced the envelope content. A weaker boost of virus expression by Staufen-1 was not sufficient to induce these morphological alterations.

CMV-Promoter Driven Codon-Optimized Expression Alters the Assembly Type and Morphology of a Reconstituted HERV-K(HML-2)

PubMed Central

Hohn, Oliver; Hanke, Kirsten; Lausch, Veronika; Zimmermann, Anja; Mostafa, Saeed; Bannert, Norbert

2014-01-01

The HERV-K(HML-2) family contains the most recently integrated and best preserved endogenized proviral sequences in the human genome. All known elements have nevertheless been subjected to mutations or deletions that render expressed particles non-infectious. Moreover, these post-insertional mutations hamper the analysis of the general biological properties of this ancient virus family. The expression of consensus sequences and sequences of elements with reverted post-insertional mutations has therefore been very instrumental in overcoming this limitation. We investigated the particle morphology of a recently reconstituted HERV-K113 element termed oriHERV-K113 using thin-section electron microscopy (EM) and could demonstrate that strong overexpression by substitution of the 5'LTR for a CMV promoter and partial codon optimization altered the virus assembly type and morphology. This included a conversion from the regular C-type to an A-type morphology with a mass of cytoplasmic immature cores tethered to the cell membrane and the membranes of vesicles. Overexpression permitted the release and maturation of virions but reduced the envelope content. A weaker boost of virus expression by Staufen-1 was not sufficient to induce these morphological alterations. PMID:25393897

40 CFR 278.2 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 28 2013-07-01 2013-07-01 false Applicability. 278.2 Section 278.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) CRITERIA FOR THE MANAGEMENT OF GRANULAR MINE TAILINGS (CHAT) IN ASPHALT CONCRETE AND PORTLAND CEMENT CONCRETE IN...

40 CFR 278.2 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 28 2012-07-01 2012-07-01 false Applicability. 278.2 Section 278.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) CRITERIA FOR THE MANAGEMENT OF GRANULAR MINE TAILINGS (CHAT) IN ASPHALT CONCRETE AND PORTLAND CEMENT CONCRETE IN...

40 CFR 278.2 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 27 2014-07-01 2014-07-01 false Applicability. 278.2 Section 278.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) CRITERIA FOR THE MANAGEMENT OF GRANULAR MINE TAILINGS (CHAT) IN ASPHALT CONCRETE AND PORTLAND CEMENT CONCRETE IN...

40 CFR 278.2 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 27 2011-07-01 2011-07-01 false Applicability. 278.2 Section 278.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) CRITERIA FOR THE MANAGEMENT OF GRANULAR MINE TAILINGS (CHAT) IN ASPHALT CONCRETE AND PORTLAND CEMENT CONCRETE IN...

40 CFR 278.2 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Applicability. 278.2 Section 278.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) CRITERIA FOR THE MANAGEMENT OF GRANULAR MINE TAILINGS (CHAT) IN ASPHALT CONCRETE AND PORTLAND CEMENT CONCRETE IN...

20 CFR 404.278 - Additional cost-of-living increase.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Section 404.278 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Computing Primary Insurance Amounts Cost-Of-Living Increases § 404.278...) Measuring period for the additional increase—(1) Beginning. To compute the additional increase, we begin...

40 CFR 278.4 - Certification and recordkeeping requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 28 2013-07-01 2013-07-01 false Certification and recordkeeping requirements. 278.4 Section 278.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) CRITERIA FOR THE MANAGEMENT OF GRANULAR MINE TAILINGS (CHAT) IN ASPHALT CONCRETE AND...

40 CFR 278.4 - Certification and recordkeeping requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 27 2011-07-01 2011-07-01 false Certification and recordkeeping requirements. 278.4 Section 278.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) CRITERIA FOR THE MANAGEMENT OF GRANULAR MINE TAILINGS (CHAT) IN ASPHALT CONCRETE AND...

40 CFR 278.4 - Certification and recordkeeping requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 28 2012-07-01 2012-07-01 false Certification and recordkeeping requirements. 278.4 Section 278.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) CRITERIA FOR THE MANAGEMENT OF GRANULAR MINE TAILINGS (CHAT) IN ASPHALT CONCRETE AND...

40 CFR 278.4 - Certification and recordkeeping requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 27 2014-07-01 2014-07-01 false Certification and recordkeeping requirements. 278.4 Section 278.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) CRITERIA FOR THE MANAGEMENT OF GRANULAR MINE TAILINGS (CHAT) IN ASPHALT CONCRETE AND...

Identification of a 27.8 kDa protein from flounder gill cells involved in lymphocystis disease virus binding and infection.

PubMed

Wang, Mu; Sheng, Xiu-Zhen; Xing, Jing; Tang, Xiao-Qian; Zhan, Wen-Bin

2011-03-16

In vitro, lymphocystis disease virus (LCDV) infection of flounder gill (FG) cell cultures causes obvious cytopathic effect (CPE). We describe attempts to isolate and characterize the LCDV-binding molecule(s) on the plasma membrane of FG cells that were responsible for virus entry. The results showed that the co-immunoprecipitation assay detected a 27.8 kDa molecule from FG cells that bound to LCDV. In a blocking ELISA, pre-incubation of FG cell membrane proteins with the specific antiserum developed against the 27.8 kDa protein could block LCDV binding. Similarly, antiserum against 27.8 kDa protein could also inhibit LCDV infection of FG cells in vitro. Mass spectrometric analysis established that the 27.8 kDa protein and beta-actin had a strong association. These results strongly supported the possibility that the 27.8 kDa protein was the putative receptor specific for LCDV infection of FG cells.

p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and senescence in response to DNA damage.

PubMed

Gong, Lu; Gong, Hongjian; Pan, Xiao; Chang, Changqing; Ou, Zhao; Ye, Shengfan; Yin, Le; Yang, Lina; Tao, Ting; Zhang, Zhenhai; Liu, Cong; Lane, David P; Peng, Jinrong; Chen, Jun

2015-03-01

The inhibitory role of p53 in DNA double-strand break (DSB) repair seems contradictory to its tumor-suppressing property. The p53 isoform Δ113p53/Δ133p53 is a p53 target gene that antagonizes p53 apoptotic activity. However, information on its functions in DNA damage repair is lacking. Here we report that Δ113p53 expression is strongly induced by γ-irradiation, but not by UV-irradiation or heat shock treatment. Strikingly, Δ113p53 promotes DNA DSB repair pathways, including homologous recombination, non-homologous end joining and single-strand annealing. To study the biological significance of Δ113p53 in promoting DNA DSB repair, we generated a zebrafish Δ113p53(M/M) mutant via the transcription activator-like effector nuclease technique and found that the mutant is more sensitive to γ-irradiation. The human ortholog, Δ133p53, is also only induced by γ-irradiation and functions to promote DNA DSB repair. Δ133p53-knockdown cells were arrested at the G2 phase at the later stage in response to γ-irradiation due to a high level of unrepaired DNA DSBs, which finally led to cell senescence. Furthermore, Δ113p53/Δ133p53 promotes DNA DSB repair via upregulating the transcription of repair genes rad51, lig4 and rad52 by binding to a novel type of p53-responsive element in their promoters. Our results demonstrate that Δ113p53/Δ133p53 is an evolutionally conserved pro-survival factor for DNA damage stress by preventing apoptosis and promoting DNA DSB repair to inhibit cell senescence. Our data also suggest that the induction of Δ133p53 expression in normal cells or tissues provides an important tolerance marker for cancer patients to radiotherapy.

7 CFR 278.3 - Participation of wholesale food concerns.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 4 2014-01-01 2014-01-01 false Participation of wholesale food concerns. 278.3 Section 278.3 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM PARTICIPATION OF RETAIL FOOD...

7 CFR 278.2 - Participation of retail food stores.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 4 2014-01-01 2014-01-01 false Participation of retail food stores. 278.2 Section 278.2 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM PARTICIPATION OF RETAIL FOOD STORES...

40 CFR 52.278 - Oxides of nitrogen control.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Oxides of nitrogen control. 52.278... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.278 Oxides of nitrogen control. (a) The following regulations are disapproved because they relax the control of nitrogen oxides...

40 CFR 52.278 - Oxides of nitrogen control.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Oxides of nitrogen control. 52.278... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.278 Oxides of nitrogen control. (a) The following regulations are disapproved because they relax the control of nitrogen oxides...

40 CFR 52.278 - Oxides of nitrogen control.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Oxides of nitrogen control. 52.278... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.278 Oxides of nitrogen control. (a) The following regulations are disapproved because they relax the control of nitrogen oxides...

40 CFR 52.278 - Oxides of nitrogen control.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Oxides of nitrogen control. 52.278... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.278 Oxides of nitrogen control. (a) The following regulations are disapproved because they relax the control of nitrogen oxides...

18 CFR 2.78 - Utilization and conservation of natural resources-natural gas.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Utilization and conservation of natural resources-natural gas. 2.78 Section 2.78 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND...

18 CFR 2.78 - Utilization and conservation of natural resources-natural gas.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Utilization and conservation of natural resources-natural gas. 2.78 Section 2.78 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND...

18 CFR 2.78 - Utilization and conservation of natural resources-natural gas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Utilization and conservation of natural resources-natural gas. 2.78 Section 2.78 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND...

18 CFR 2.78 - Utilization and conservation of natural resources-natural gas.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Utilization and conservation of natural resources-natural gas. 2.78 Section 2.78 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND...

Simulators for Mariner Training and Licensing: Guidelines for Deck Officer Training Systems.

DTIC Science & Technology

1982-12-01

Information regarding the three major elements of the training system - the simu- lator design , the training program structure, and the instructor...1.1.2 Empirical Research/ Experimentation Phase ........................................ 1 1.1.3 Major Product...3 3.2 Simulator Design (Critical Characteristics) ......................................... 13 3.2.1 Visual Scee

32 CFR 11.3 - General.

Code of Federal Regulations, 2010 CFR

2010-07-01

... crimes and elements derive from the law of armed conflict, a body of law that is sometimes referred to as... with that body of law, are triable by military commission. Because this document is declarative of... of other laws. No conclusion regarding the applicability or persuasive authority of other bodies of...

32 CFR 11.3 - General.

Code of Federal Regulations, 2014 CFR

2014-07-01

... crimes and elements derive from the law of armed conflict, a body of law that is sometimes referred to as... with that body of law, are triable by military commission. Because this document is declarative of... of other laws. No conclusion regarding the applicability or persuasive authority of other bodies of...

32 CFR 11.3 - General.

Code of Federal Regulations, 2013 CFR

2013-07-01

... crimes and elements derive from the law of armed conflict, a body of law that is sometimes referred to as... with that body of law, are triable by military commission. Because this document is declarative of... of other laws. No conclusion regarding the applicability or persuasive authority of other bodies of...

32 CFR 11.3 - General.

Code of Federal Regulations, 2011 CFR

2011-07-01

... crimes and elements derive from the law of armed conflict, a body of law that is sometimes referred to as... with that body of law, are triable by military commission. Because this document is declarative of... of other laws. No conclusion regarding the applicability or persuasive authority of other bodies of...

32 CFR 11.3 - General.

Code of Federal Regulations, 2012 CFR

2012-07-01

... crimes and elements derive from the law of armed conflict, a body of law that is sometimes referred to as... with that body of law, are triable by military commission. Because this document is declarative of... of other laws. No conclusion regarding the applicability or persuasive authority of other bodies of...

7 CFR 1822.278 - Special requirements for RHS section 523 loans (loans to organizations providing sites for self...

Code of Federal Regulations, 2011 CFR

2011-01-01

... to organizations providing sites for self-help housing). 1822.278 Section 1822.278 Agriculture... organizations providing sites for self-help housing). Loans to organizations which will provide sites for self... exceptions: (a) Eligibility. The applicant must be a nonprofit organization engaged in assisting self-help...

7 CFR 1822.278 - Special requirements for RHS section 523 loans (loans to organizations providing sites for self...

Code of Federal Regulations, 2013 CFR

2013-01-01

... to organizations providing sites for self-help housing). 1822.278 Section 1822.278 Agriculture... organizations providing sites for self-help housing). Loans to organizations which will provide sites for self... exceptions: (a) Eligibility. The applicant must be a nonprofit organization engaged in assisting self-help...

7 CFR 1822.278 - Special requirements for RHS section 523 loans (loans to organizations providing sites for self...

Code of Federal Regulations, 2012 CFR

2012-01-01

... to organizations providing sites for self-help housing). 1822.278 Section 1822.278 Agriculture... organizations providing sites for self-help housing). Loans to organizations which will provide sites for self... exceptions: (a) Eligibility. The applicant must be a nonprofit organization engaged in assisting self-help...

7 CFR 1822.278 - Special requirements for RHS section 523 loans (loans to organizations providing sites for self...

Code of Federal Regulations, 2014 CFR

2014-01-01

... to organizations providing sites for self-help housing). 1822.278 Section 1822.278 Agriculture... organizations providing sites for self-help housing). Loans to organizations which will provide sites for self... exceptions: (a) Eligibility. The applicant must be a nonprofit organization engaged in assisting self-help...

7 CFR 1822.278 - Special requirements for RHS section 523 loans (loans to organizations providing sites for self...

Code of Federal Regulations, 2010 CFR

2010-01-01

... to organizations providing sites for self-help housing). 1822.278 Section 1822.278 Agriculture... organizations providing sites for self-help housing). Loans to organizations which will provide sites for self... exceptions: (a) Eligibility. The applicant must be a nonprofit organization engaged in assisting self-help...

40 CFR 278.3 - Criteria for use of chat in Federally funded transportation projects.

Code of Federal Regulations, 2010 CFR

2010-07-01

... funded transportation projects. 278.3 Section 278.3 Protection of Environment ENVIRONMENTAL PROTECTION... Leaching Procedure (SPLP) tests are conducted on the proposed material using EPA SW-846 Method 1312...) EPA (or a State environmental Agency, if it chooses to do so) has determined, based on a site-specific...

7 CFR 278.9 - Implementation of amendments relating to the participation of retail food stores, wholesale food...

Code of Federal Regulations, 2010 CFR

2010-01-01

... participation of retail food stores, wholesale food concerns and insured financial institutions. 278.9 Section 278.9 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM PARTICIPATION OF RETAIL FOOD STORES...

7 CFR 278.7 - Determination and disposition of claims-retail food stores and wholesale food concerns.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false Determination and disposition of claims-retail food stores and wholesale food concerns. 278.7 Section 278.7 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION...

K2-113: a dense hot-Jupiter transiting a solar analogue

NASA Astrophysics Data System (ADS)

Espinoza, Néstor; Rabus, Markus; Brahm, Rafael; Jones, Matías; Jordán, Andrés; Rojas, Felipe; Drass, Holger; Vučković, Maja; Hartman, Joel D.; Jenkins, James S.; Cortés, Cristián

2017-11-01

We present the discovery of K2-113, a dense hot-Jupiter discovered using photometry from Campaign 8 of the Kepler-2 (K2) mission and high-resolution spectroscopic follow-up obtained with the FEROS spectrograph. The planet orbits a V = 13.68 solar analogue in a P=5.817 60^{+0.000 03}_{-0.000 03} d orbit, and has a radius of 0.93^{+0.10}_{-0.07}R_J and a mass of 1.29^{+0.13}_{-0.14}M_J. With a density of 1.97^{+0.60}_{-0.53} g cm-3, the planet is among the densest systems known having masses below 2 MJ and T_eq > 1000, and is just above the temperature limit at which inflation mechanisms are believed to start being important. Based on its mass and radius, we estimate that K2-113 should have a heavy element content of the order of ˜110 M⊕ or greater.

26 CFR 1.278-1 - Capital expenditures incurred in planting and developing citrus and almond groves.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 26 Internal Revenue 3 2011-04-01 2011-04-01 false Capital expenditures incurred in planting and... § 1.278-1 Capital expenditures incurred in planting and developing citrus and almond groves. (a... regard to section 278 or this section) which is attributable to the planting, cultivation, maintenance...

25 CFR 1000.278 - Does this coverage extend to subcontractors of self-governance AFAs?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Does this coverage extend to subcontractors of self-governance AFAs? 1000.278 Section 1000.278 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... subcontractors of self-governance AFAs? No, subcontractors or subgrantees providing services to a Pub. L. 93-638...

The prevalence of human immunodeficiency virus and sexually transmitted infections among female sex workers in Shiraz, South of Iran: by respondent-driven sampling.

PubMed

Kazerooni, Parvin Afsar; Motazedian, Nasrin; Motamedifar, Mohammad; Sayadi, Mehrab; Sabet, Mojghan; Lari, Mahmood Amini; Kamali, Kianoush

2014-02-01

As a concentrated epidemic, human immunodeficiency virus (HIV) is spreading rapidly in one or more groups in Iran, but in the general population its prevalence is relatively low. Female sex workers (FSWs) and their partners are at greater risk for HIV infection. To determine the prevalence of HIV and sexually transmitted infections (STIs) including gonorrhoea, Chlamydia, herpes simplex type 2 and syphilis among FSWs. We conducted a cross-sectional study of 278 FSWs in Shiraz, by using respondent-driven sampling, from June to March 2010. The recruitment chain started with 14 seeds, and FSWs were tested for HIV, syphilis, herpes simplex type 2, gonorrhoea and Chlamydia. HIV prevalence was 4.7% (13/278); the most prevalent STI was herpes simplex type 2, 9.7% (27/278), followed by Chlamydia 9% (25/278), gonorrhoea 1.4% (4/278) and syphilis (0/278). The FSWs reported drug use (69.9%) of which 16.4% had history of injecting drug use. Unprotected sex in the past month was reported by 24.4% of FSWs. Urgent education and risk reduction programmes are needed in this population.

49 CFR Appendix to Subpart G of... - Required Knowledge and Skills-Sample Guidelines

Code of Federal Regulations, 2010 CFR

2010-10-01

... knowledge and skills tests that it administers to CDL applicants. This appendix closely follows the... discretion provided their CDL program tests for the general areas of knowledge and skill specified in §§ 383.111 and 383.113. Examples of specific knowledge elements (a) Safe operations regulations. Driver...

77 FR 16435 - Transmission Relay Loadability Reliability Standard

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-21

... are designed to read electrical measurements, such as current, voltage, and frequency, and can be set... an element of the system under its protection, it sends a signal to an interrupting device(s) (such... their relays according to one of thirteen specific settings (sub-parts R1.1 through R1.13) designed to...

NSWC Library of Mathematics Subroutines

DTIC Science & Technology

1990-01-01

sufficiently many zero elements for it to be worthwhile to use special techniques that avoid storing and operating with the zeros.U The scheme adopted by the... general purpose numerical mathematics subroutines began. The subroutines are written in ANSI standard Fortran. This manual describes the subroutines in...PLCOPYDPCOPY ............ ...................... 113 Addition of Polynomials - PADD ,DPADD ............. .................. I.... 115 Subtraction of

Development of an Effective Special Therapy Bed Management System at Walter Reed Army Medical Center.

DTIC Science & Technology

1991-12-01

Patillo, 1990). The administrative support element attempted to pattern itself after the clinical model, hoping to better manage shortages of personnel...Material ManaQement Quarterly, 11(3), 36-48. Thomas, C. (1989). Specialty beds: Decision making made easy. Ostomy -Wound Management, 23, 51-59. Thomson

Petrology of Ortsog-Uul peridotite-gabbro massif in Western Mongolia

NASA Astrophysics Data System (ADS)

Shapovalova, M.; Tolstykh, N.; Shelepaev, R.; Cherdantseva, M.

2017-12-01

The Ortsog-Uul mafic-ultramafic massif of Western Mongolia is located in a tectonic block with overturned bedding. The massif hosts two intrusions: a rhythmically-layered peridotite-gabbro association (Intrusion 1) and massive Bt-bearing amphibole-olivine gabbro (Intrusion 2). Intrusions 1 and 2 have different petrology features. Early Intrusion 1 (278±2.5Ma) is characterized by lower concentrations of alkalis, titanium and phosphorus than late Intrusion 2 (272±2Ma). The chondrite-normalized REE and primitive mantle-normalized rare elements patterns of Ortsog-Uul intrusions have similar curves of elements distribution. However, Intrusion 2 is characterized higher contents of REE and rare elements. High concentrations of incompatible elements are indicative of strong fractionation process. It has been suggested that Intrusions 1 and 2 derived from compositionally different parental melts. Model calculations (COMAGMAT-3.57) show that parental melts of two intrusions were close to high-Mg picrobasaltic magmas. The concentration of MgO in melt is 16.21 (Intrusion 1) and 16.17 (Intrusion 2). Isotopic data of Ortsog-Uul magmatic rocks exhibit different values of εNd (positive and negative) for Intrusion 1 and 2, respectively.

Actinide targets for the synthesis of super-heavy elements

DOE PAGES

Roberto, J.; Alexander, Charles W.; Boll, Rose Ann; ...

2015-06-18

Since 2000, six new super-heavy elements with atomic numbers 113 through 118 have been synthesized in hot fusion reactions of 48Ca beams on actinide targets. These target materials, including 242Pu, 244Pu, 243Am, 245Cm, 248Cm, 249Cf, and 249Bk, are available in very limited quantities and require specialized production and processing facilities resident in only a few research centers worldwide. This report describes the production and chemical processing of heavy actinide materials for super-heavy element research, current availabilities of these materials, and related target fabrication techniques. The impact of actinide materials in super-heavy element discovery is reviewed, and strategies for enhancing themore » production of rare actinides including 249Bk, 251Cf, and 254Es are described.« less

Monoclonal antibodies against 27.8 kDa protein receptor efficiently block lymphocystis disease virus infection in flounder Paralichthys olivaceus gill cells.

PubMed

Sheng, Xiu-Zhen; Wang, Mu; Xing, Jing; Zhan, Wen-Bin

2012-08-13

In previous research using co-immunoprecipitation, a 27.8 kDa protein in flounder Paralichthys olivaceus gill (FG) cells was found to bind lymphocystis disease virus (LCDV). In this paper, 13 hybridomas secreting monoclonal antibodies (MAbs) against the 27.8 kDa protein were obtained, and 2 MAbs designated as 2G11 and 3D9 were cloned by limiting dilution. Analyzed by indirect enzyme-linked immunosorbent assay (ELISA) and western blotting, the MAbs specifically reacted with the 27.8 kDa protein of FG cells. Confocal fluorescence microscopy and immunogold electron microscopy (IEM) provided evidence that the epitopes recognized by these MAbs were located primarily on the cell membrane and occasionally in the cytoplasm near the cell membrane of FG cells. The MAbs could block LCDV binding after MAbs were pre-incubated with isolated membrane proteins of FG cells in a blocking ELISA, and MAbs also could inhibit LCDV infection of FG cells in culture. Moreover, several target tissues of LCDV in flounder, including gill, stomach, intestine and liver, displayed the presence of the LCDV receptor-27.8 kDa. These results strongly supported the possibility that the 27.8 kDa protein is the putative receptor specific for LCDV infection of FG cells in flounder.

A 32 kDa viral attachment protein of lymphocystis disease virus (LCDV) specifically interacts with a 27.8 kDa cellular receptor from flounder (Paralichthys olivaceus).

PubMed

Zhong, Ying; Fei, Chenjie; Tang, Xiaoqian; Zhan, Wenbin; Sheng, Xiuzhen

2017-06-01

The 27.8 kDa protein in flounder gill (FG) cells was previously proved to be a receptor specific for lymphocystis disease virus (LCDV) entry and infection. In this paper, a 32 kDa viral attachment protein (VAP) of LCDV specifically binding to the 27.8 kDa receptor (27.8R) was found by far-Western blotting coupled with monoclonal antibodies (MAbs) against 27.8R. The 32 kDa protein was confirmed to be encoded by the open reading frame (ORF) 038 gene in LCDV-C, and predicted to contain a putative transmembrane region, multiple N-myristoylation and glycosylation sites and phosphorylation motifs. The expression plasmid of pET-32a-ORF038 was constructed and the recombinant VAP (rVAP) was obtained. Rabbit polyclonal antibodies against the rVAP were prepared and could recognize the rVAP and 32 kDa protein in LCDV. Immunogold electron microscopy showed that the 32 kDa protein was located on the surface of LCDV particles. Immunofluorescence assay demonstrated that the rVAP could bind to the 27.8R on the cell membrane of the FG monolayer and the anti-27.8R MAbs could block the rVAP binding. Pre-incubation of the rVAP with FG cells before LCDV infection, or pre-incubation of LCDV with the antibodies against the rVAP, could significantly decrease the LCDV copy numbers (P<0.05) and delay the emergence of cytopathic effects in FG cells in a dose-dependent manner. These results indicated for the first time that the 32 kDa protein functioned as an attachment protein for the initial attachment and entry of LCDV, and the interaction of the 32 kDa VAP with the 27.8R-initiated LCDV infection.

National evidence on the use of shared decision making in prostate-specific antigen screening.

PubMed

Han, Paul K J; Kobrin, Sarah; Breen, Nancy; Joseph, Djenaba A; Li, Jun; Frosch, Dominick L; Klabunde, Carrie N

2013-01-01

Recent clinical practice guidelines on prostate cancer screening using the prostate-specific antigen (PSA) test (PSA screening) have recommended that clinicians practice shared decision making-a process involving clinician-patient discussion of the pros, cons, and uncertainties of screening. We undertook a study to determine the prevalence of shared decision making in both PSA screening and nonscreening, as well as patient characteristics associated with shared decision making. A nationally representative sample of 3,427 men aged 50 to 74 years participating in the 2010 National Health Interview Survey responded to questions on the extent of shared decision making (past physician-patient discussion of advantages, disadvantages, and scientific uncertainty associated with PSA screening), PSA screening intensity (tests in past 5 years), and sociodemographic and health-related characteristics. Nearly two-thirds (64.3%) of men reported no past physician-patient discussion of advantages, disadvantages, or scientific uncertainty (no shared decision making); 27.8% reported discussion of 1 to 2 elements only (partial shared decision making); 8.0% reported discussion of all 3 elements (full shared decision making). Nearly one-half (44.2%) reported no PSA screening, 27.8% reported low-intensity (less-than-annual) screening, and 25.1% reported high-intensity (nearly annual) screening. Absence of shared decision making was more prevalent in men who were not screened; 88% (95% CI, 86.2%-90.1%) of nonscreened men reported no shared decision making compared with 39% (95% CI, 35.0%-43.3%) of men undergoing high-intensity screening. Extent of shared decision making was associated with black race, Hispanic ethnicity, higher education, health insurance, and physician recommendation. Screening intensity was associated with older age, higher education, usual source of medical care, and physician recommendation, as well as with partial vs no or full shared decision making. Most US men report little shared decision making in PSA screening, and the lack of shared decision making is more prevalent in nonscreened than in screened men. Screening intensity is greatest with partial shared decision making, and different elements of shared decision making are associated with distinct patient characteristics. Shared decision making needs to be improved in decisions for and against PSA screening.

Identification of the protease cleavage sites in a reconstituted Gag polyprotein of an HERV-K(HML-2) element

PubMed Central

2011-01-01

Background The human genome harbors several largely preserved HERV-K(HML-2) elements. Although this retroviral family comes closest of all known HERVs to producing replication competent virions, mutations acquired during their chromosomal residence have rendered them incapable of expressing infectious particles. This also holds true for the HERV-K113 element that has conserved open reading frames (ORFs) for all its proteins in addition to a functional LTR promoter. Uncertainty concerning the localization and impact of post-insertional mutations has greatly hampered the functional characterization of these ancient retroviruses and their proteins. However, analogous to other betaretroviruses, it is known that HERV-K(HML-2) virions undergo a maturation process during or shortly after release from the host cell. During this process, the subdomains of the Gag polyproteins are released by proteolytic cleavage, although the nature of the mature HERV-K(HML-2) Gag proteins and the exact position of the cleavage sites have until now remained unknown. Results By aligning the amino acid sequences encoded by the gag-pro-pol ORFs of HERV-K113 with the corresponding segments from 10 other well-preserved human specific elements we identified non-synonymous post-insertional mutations that have occurred in this region of the provirus. Reversion of these mutations and a partial codon optimization facilitated the large-scale production of maturation-competent HERV-K113 virus-like particles (VLPs). The Gag subdomains of purified mature VLPs were separated by reversed-phase high-pressure liquid chromatography and initially characterized using specific antibodies. Cleavage sites were identified by mass spectrometry and N-terminal sequencing and confirmed by mutagenesis. Our results indicate that the gag gene product Pr74Gag of HERV-K(HML-2) is processed to yield p15-MA (matrix), SP1 (spacer peptide of 14 amino acids), p15, p27-CA (capsid), p10-NC (nucleocapsid) and two C-terminally encoded glutamine- and proline-rich peptides, QP1 and QP2, spanning 23 and 19 amino acids, respectively. Conclusions Expression of reconstituted sequences of original HERV elements is an important tool for studying fundamental aspects of the biology of these ancient viruses. The analysis of HERV-K(HML-2) Gag processing and the nature of the mature Gag proteins presented here will facilitate further studies of the discrete functions of these proteins and of their potential impact on the human host. PMID:21554716

Identification of the protease cleavage sites in a reconstituted Gag polyprotein of an HERV-K(HML-2) element.

PubMed

George, Maja; Schwecke, Torsten; Beimforde, Nadine; Hohn, Oliver; Chudak, Claudia; Zimmermann, Anja; Kurth, Reinhard; Naumann, Dieter; Bannert, Norbert

2011-05-09

The human genome harbors several largely preserved HERV-K(HML-2) elements. Although this retroviral family comes closest of all known HERVs to producing replication competent virions, mutations acquired during their chromosomal residence have rendered them incapable of expressing infectious particles. This also holds true for the HERV-K113 element that has conserved open reading frames (ORFs) for all its proteins in addition to a functional LTR promoter. Uncertainty concerning the localization and impact of post-insertional mutations has greatly hampered the functional characterization of these ancient retroviruses and their proteins. However, analogous to other betaretroviruses, it is known that HERV-K(HML-2) virions undergo a maturation process during or shortly after release from the host cell. During this process, the subdomains of the Gag polyproteins are released by proteolytic cleavage, although the nature of the mature HERV-K(HML-2) Gag proteins and the exact position of the cleavage sites have until now remained unknown. By aligning the amino acid sequences encoded by the gag-pro-pol ORFs of HERV-K113 with the corresponding segments from 10 other well-preserved human specific elements we identified non-synonymous post-insertional mutations that have occurred in this region of the provirus. Reversion of these mutations and a partial codon optimization facilitated the large-scale production of maturation-competent HERV-K113 virus-like particles (VLPs). The Gag subdomains of purified mature VLPs were separated by reversed-phase high-pressure liquid chromatography and initially characterized using specific antibodies. Cleavage sites were identified by mass spectrometry and N-terminal sequencing and confirmed by mutagenesis. Our results indicate that the gag gene product Pr74Gag of HERV-K(HML-2) is processed to yield p15-MA (matrix), SP1 (spacer peptide of 14 amino acids), p15, p27-CA (capsid), p10-NC (nucleocapsid) and two C-terminally encoded glutamine- and proline-rich peptides, QP1 and QP2, spanning 23 and 19 amino acids, respectively. Expression of reconstituted sequences of original HERV elements is an important tool for studying fundamental aspects of the biology of these ancient viruses. The analysis of HERV-K(HML-2) Gag processing and the nature of the mature Gag proteins presented here will facilitate further studies of the discrete functions of these proteins and of their potential impact on the human host.

Effect of rest interval length on bench press performance in boys, teens, and men.

PubMed

Faigenbaum, Avery D; Ratamess, Nicholas A; McFarland, Jim; Kaczmarek, Jon; Coraggio, Michael J; Kang, Jie; Hoffman, Jay R

2008-11-01

The purpose of this study was to assess the lifting performance of boys (N = 12; age 11.3 +/- 0.8 yr), teens (N = 13; age 13.6 +/- 0.6 yr), and men (N = 17; age 21.4 +/- 2.1 yr) to various rest interval (RI) lengths on the bench press exercise. Each subject performed 3 sets with a 10 repetition maximum load and a 1, 2, and 3 min RI between sets. Significant differences in lifting performance between age groups were observed within each RI for selected sets with boys and teens performing significantly more total repetitions than adults following protocols with 1 min (27.9 +/- 3.1, 26.9 +/- 3.9, and 18.2 +/- 4.1, respectively), 2 min (29.6 +/- 1.0, 27.8 +/- 3.5, and 21.4 +/- .1, respectively) and 3 min (30.0 +/- 0.0, 28.8 +/- 2.4, and 23.9 +/- 5.3, respectively) RIs. Significant differences in average velocity and average power between age groups were also observed. These findings indicate that boys and teens are better able to maintain muscle performance during intermittent moderate-intensity resistance exercise as compared with men.

Synthesis of Textures Using Simultaneous Autoregressive Models.

DTIC Science & Technology

1981-07-01

CHELLAPPA AFOSR-77-3271 UNCLASSIFIED TR- 1082 AFOSR-TR-81-0795 NL 110~2.8 .113:’I0 111.02. 1111I25 II.4~* 1.6 MICROCOPY R[ SOLUTION ILS1 CHARI ,.TR- 81...NUMBER TR- 1082 . 7. AUTHOR(*) S. CONTRACT OR GRANT NUMBER(&) R. Chella-)pa AFOSR-77-3271 9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT

Identification and Characterization of a Novel Broad-Spectrum Virus Entry Inhibitor

PubMed Central

Chou, Yi-ying; Cuevas, Christian; Carocci, Margot; Stubbs, Sarah H.; Ma, Minghe; Cureton, David K.; Evesson, Frances; He, Kangmin; Yang, Priscilla L.; Whelan, Sean P.

2016-01-01

ABSTRACT Virus entry into cells is a multistep process that often requires the subversion of subcellular machineries. A more complete understanding of these steps is necessary to develop new antiviral strategies. While studying the potential role of the actin network and one of its master regulators, the small GTPase Cdc42, during Junin virus (JUNV) entry, we serendipitously uncovered the small molecule ZCL278, reported to inhibit Cdc42 function as an entry inhibitor for JUNV and for vesicular stomatitis virus, lymphocytic choriomeningitis virus, and dengue virus but not for the nonenveloped poliovirus. Although ZCL278 did not interfere with JUNV attachment to the cell surface or virus particle internalization into host cells, it prevented the release of JUNV ribonucleoprotein cores into the cytosol and decreased pH-mediated viral fusion with host membranes. We also identified SVG-A astroglial cell-derived cells to be highly permissive for JUNV infection and generated new cell lines expressing fluorescently tagged Rab5c or Rab7a or lacking Cdc42 using clustered regularly interspaced short palindromic repeat (CRISPR)-caspase 9 (Cas9) gene-editing strategies. Aided by these tools, we uncovered that perturbations in the actin cytoskeleton or Cdc42 activity minimally affect JUNV entry, suggesting that the inhibitory effect of ZCL278 is not mediated by ZCL278 interfering with the activity of Cdc42. Instead, ZCL278 appears to redistribute viral particles from endosomal to lysosomal compartments. ZCL278 also inhibited JUNV replication in a mouse model, and no toxicity was detected. Together, our data suggest the unexpected antiviral activity of ZCL278 and highlight its potential for use in the development of valuable new tools to study the intracellular trafficking of pathogens. IMPORTANCE The Junin virus is responsible for outbreaks of Argentine hemorrhagic fever in South America, where 5 million people are at risk. Limited options are currently available to treat infections by Junin virus or other viruses of the Arenaviridae, making the identification of additional tools, including small-molecule inhibitors, of great importance. How Junin virus enters cells is not yet fully understood. Here we describe new cell culture models in which the cells are susceptible to Junin virus infection and to which we applied CRISPR-Cas9 genome engineering strategies to help characterize early steps during virus entry. We also uncovered ZCL278 to be a new antiviral small molecule that potently inhibits the cellular entry of the Junin virus and other enveloped viruses. Moreover, we show that ZCL278 also functions in vivo, thereby preventing Junin virus replication in a mouse model, opening the possibility for the discovery of ZCL278 derivatives of therapeutic potential. PMID:26912630

Heavy metal determinations in algae and clams and their possible employment for assessing the sea water quality criteria.

PubMed

Locatelli, C; Fabbri, D; Torsi, G

2001-01-01

An empirical criterion for a possible classification of sea water quality is proposed. It is based on the knowledge of metal content in algae (Ulva Rigida) and clams (Tapes Philippinarum), two species present in marine ecosystems. The elements considered are Hg, Cu, Pb, Cd, Zn. The analytical technique employed is Differential Pulse Anodic Stripping Voltammetry (DPASV) in the case of Cu, Pb, Cd, Zn, while the determination of mercury is obtained by the Cold Vapour Atomic Absorption Spectroscopy (CV-AAS) technique with SnCl2 as reducing agent. The analytical procedure has been verified on three standard reference materials: Sea Water BCR-CRM 403, Ulva Lactuca BCR-CRM 279 and Mussel Tissue BCR-CRM 278. For all the elements, in addition to detection limits, accuracy and precision are given: the former, expressed as relative error (e), and the latter, expressed as relative standard deviation (Sr), were in all cases lower than 6%.

STS-92 Mission Specialist Lopez-Alegria is ready to drive the M- 113

NASA Technical Reports Server (NTRS)

2000-01-01

Waiting his turn to drive the M-113 is STS-92 Mission Specialist Michael Lopez-Alegria. Part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities, the tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

KSC-00pp1326

NASA Image and Video Library

2000-09-13

With other crew members in the back, STS-92 Mission Specialist Leroy Chiao races the M-113 along the track through the scrub. Driving the M-113 is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter’s payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program

Investigation of dissipation elements in a fully developed turbulent channel flow by tomographic particle-image velocimetry

NASA Astrophysics Data System (ADS)

Schäfer, L.; Dierksheide, U.; Klaas, M.; Schröder, W.

2011-03-01

A new method to describe statistical information from passive scalar fields has been proposed by Wang and Peters ["The length-scale distribution function of the distance between extremal points in passive scalar turbulence," J. Fluid Mech. 554, 457 (2006)]. They used direct numerical simulations (DNS) of homogeneous shear flow to introduce the innovative concept. This novel method determines the local minimum and maximum points of the fluctuating scalar field via gradient trajectories, starting from every grid point in the direction of the steepest ascending and descending scalar gradients. Relying on gradient trajectories, a dissipation element is defined as the region of all the grid points, the trajectories of which share the same pair of maximum and minimum points. The procedure has also been successfully applied to various DNS fields of homogeneous shear turbulence using the three velocity components and the kinetic energy as scalar fields [L. Wang and N. Peters, "Length-scale distribution functions and conditional means for various fields in turbulence," J. Fluid Mech. 608, 113 (2008)]. In this spirit, dissipation elements are, for the first time, determined from experimental data of a fully developed turbulent channel flow. The dissipation elements are deduced from the gradients of the instantaneous fluctuation of the three velocity components u', v', and w' and the instantaneous kinetic energy k', respectively. The measurements are conducted at a Reynolds number of 1.7×104 based on the channel half-height δ and the bulk velocity U. The required three-dimensional velocity data are obtained investigating a 17.75×17.75×6 mm3 (0.355δ×0.355δ×0.12δ) test volume using tomographic particle-image velocimetry. Detection and analysis of dissipation elements from the experimental velocity data are discussed in detail. The statistical results are compared to the DNS data from Wang and Peters ["The length-scale distribution function of the distance between extremal points in passive scalar turbulence," J. Fluid Mech. 554, 457 (2006); "Length-scale distribution functions and conditional means for various fields in turbulence," J. Fluid Mech. 608, 113 (2008)]. Similar characteristics have been found especially for the pdf's of the large dissipation element length regarding the exponential decay. In agreement with the DNS results, over 99% of the experimental dissipation elements possess a length that is smaller than three times the average element length.

278. Photocopied July 1978. NOTICE TO MINE EMPLOYEES, CITIZENS AND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

278. Photocopied July 1978. NOTICE TO MINE EMPLOYEES, CITIZENS AND NON-CITIZENS, ADVISING THEM OF ACCEPTABLE BEHAVIOR AND PROPER SHOP PRACTICES DURING WARTIME. WRITTEN IN SIX LANGUAGES. C. 1918. - Quincy Mining Company, Hancock, Houghton County, MI

How elements up to 118 were reached and how to go beyond

NASA Astrophysics Data System (ADS)

Düllmann, Christoph E.

2017-11-01

The new superheavy elements with Z=113, 115, 117, and 118 were recently accepted into the periodic table and have been named. Elements with Z≥112 are predominantly produced in 48Ca-induced fusion reactions on actinide targets. This pathway is exhausted at Z=118 due to the lack of target materials with sufficiently high proton number to reach elements with Z≥119. Search experiments for yet heavier elements were performed at GSI Darmstadt and FLNR Dubna. The reactions 50Ti + 249Bk, which leads to Z=119, as well as 64Ni + 238U, 58Fe + 244Pu, 54Cr + 248Cm, and 50Ti + 249Cf, leading to Z=120, have been studied. Despite a total duration of these experiments of more than one year, neither succeeded in the identification of a new element. To obtain improved guidance for better-informed search experiments, nuclear reaction studies appear necessary and have recently started. Also technical advances will be an important pillar to this end. At GSI, work towards a new continuous-wave linear accelerator is ongoing and is briefly described.

7 CFR 274.7 - Benefit redemption by eligible households.

Code of Federal Regulations, 2014 CFR

2014-01-01

... State agency shall ensure that the EBT system is capable of providing a transaction history for a period... with §§ 278.1 and 278.2(g) of this chapter. (iii) Residents of shelters for battered women and children...

7 CFR 274.7 - Benefit redemption by eligible households.

Code of Federal Regulations, 2012 CFR

2012-01-01

... State agency shall ensure that the EBT system is capable of providing a transaction history for a period... with §§ 278.1 and 278.2(g) of this chapter. (iii) Residents of shelters for battered women and children...

7 CFR 274.7 - Benefit redemption by eligible households.

Code of Federal Regulations, 2013 CFR

2013-01-01

... State agency shall ensure that the EBT system is capable of providing a transaction history for a period... with §§ 278.1 and 278.2(g) of this chapter. (iii) Residents of shelters for battered women and children...

Structures to Resist the Effects of Accidental Explosions

DTIC Science & Technology

1990-11-01

Mott, R.I., A Theory of Fragmentation, Army Operational Research Group Memorandun, 113-AC-6427, Great Britain, 1943. 77. Non -Nuclear Weapons Effects...58.1. General Elements which protect non -sensitive explosives may be designed for controlled post-failure fragments with a substantial cost savings...6-49.3.2. Platform Characteristics A platform for group mounted systems offers great flexibility in controlling the center of gravity of the

National Evidence on the Use of Shared Decision Making in Prostate-Specific Antigen Screening

PubMed Central

Han, Paul K. J.; Kobrin, Sarah; Breen, Nancy; Joseph, Djenaba A.; Li, Jun; Frosch, Dominick L.; Klabunde, Carrie N.

2013-01-01

PURPOSE Recent clinical practice guidelines on prostate cancer screening using the prostate-specific antigen (PSA) test (PSA screening) have recommended that clinicians practice shared decision making—a process involving clinician-patient discussion of the pros, cons, and uncertainties of screening. We undertook a study to determine the prevalence of shared decision making in both PSA screening and nonscreening, as well as patient characteristics associated with shared decision making. METHODS A nationally representative sample of 3,427 men aged 50 to 74 years participating in the 2010 National Health Interview Survey responded to questions on the extent of shared decision making (past physician-patient discussion of advantages, disadvantages, and scientific uncertainty associated with PSA screening), PSA screening intensity (tests in past 5 years), and sociodemographic and health-related characteristics. RESULTS Nearly two-thirds (64.3%) of men reported no past physician-patient discussion of advantages, disadvantages, or scientific uncertainty (no shared decision making); 27.8% reported discussion of 1 to 2 elements only (partial shared decision making); 8.0% reported discussion of all 3 elements (full shared decision making). Nearly one-half (44.2%) reported no PSA screening, 27.8% reported low-intensity (less-than-annual) screening, and 25.1% reported high-intensity (nearly annual) screening. Absence of shared decision making was more prevalent in men who were not screened; 88% (95% CI, 86.2%–90.1%) of nonscreened men reported no shared decision making compared with 39% (95% CI, 35.0%–43.3%) of men undergoing high-intensity screening. Extent of shared decision making was associated with black race, Hispanic ethnicity, higher education, health insurance, and physician recommendation. Screening intensity was associated with older age, higher education, usual source of medical care, and physician recommendation, as well as with partial vs no or full shared decision making. CONCLUSIONS Most US men report little shared decision making in PSA screening, and the lack of shared decision making is more prevalent in nonscreened than in screened men. Screening intensity is greatest with partial shared decision making, and different elements of shared decision making are associated with distinct patient characteristics. Shared decision making needs to be improved in decisions for and against PSA screening. PMID:23835816

International comparison CCQM-K113—noble gas mixture

NASA Astrophysics Data System (ADS)

Lim, Jeong Sik; Lee, Jinbok; Moon, Dongmin; Tshilongo, James; Qiao, Han; Shuguo, Hu; Tiqiang, Zhang; Kelley, Michael E.; Rhoderick, George C.; Konopelko, L. A.; Kolobova, A. V.; Vasserman, I. I.; Zavyalov, S. V.; Gromova, E. V.; Efremova, O. V.

2017-01-01

Noble gases are one of the key elements used in the various processes of the bulbs industry, automotive industry, space industry, lasers industry, display industry as well as the semiconductor industry. Considering continuous growth, the provision of a reliable standard is required for those industries to improve their productivity. In this report, a result of the key comparison, CCQM-K113: noble gas mixture, is presented. Nominal amount-of-substance fractions of argon, neon, krypton, and xenon in helium are 20, 10, 2, and 1 cmol/mol, respectively. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

STS-92 Mission Specialist Chiao is ready to drive the M-113

NASA Technical Reports Server (NTRS)

2000-01-01

STS-92 Mission Specialist Leroy Chiao gets into the driver's side for his turn to drive the M-113, part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. Behind him are Pilot Pam Melroy (left) and Mission Specialist Michael Lopez-Alegria. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

STS-92 Mission Specialist Wisoff is ready to drive the M-113

NASA Technical Reports Server (NTRS)

2000-01-01

STS-92 Mission Specialist Jeff Wisoff happily anticipates his chance to drive the M-113 he is in. Behind him are Commander Brian Duffy (left) and Mission Specialist Leroy Chiao, along with other crew members. Part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities, the tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

Mobilization and Defense Management Technical Reports Series. Mobilization Studies Program Report. Selective Service Boards. Will They Be Ready?

DTIC Science & Technology

1983-05-01

Element (W)I (W2)2 Factors Male 87.5 81.1 +6.4 Sex Female 12.5 18.9 -6.4 Married to.@ 81.7 +18.3 Marital Status Single 6.0 18.3 -18.3 ( 30 0.8 6.9 -6.9...March 1982. i0 ~16l Table 2.1 Demographic Data on Local Boards. (33:12) Number of Local Boards 2,113 Board Positions 16,560 Sex of Board membe s...Effort and ~Reward (n - 175) Actual Expected Effort Response Response Reward Element (%)I (,) 2 Factor3 Male 83.9 81.1 +2.8 Sex Female 16.1 18.9 -2.8

Research and Studies Directory for Manpower, Personnel, and Training

DTIC Science & Technology

1990-05-01

COFOD R* LICA SYSTEMS INC 703-359-0996 SMART CONTRACT PREPARATION EXPEDITER COLLINS H* ARMY TRAINING AND DOCTRINE COMMAND 205-848-3174 BATTLEFIELD...TECHNICAL SUPPORT FORESTER J HUMAN ENGINEERING LAB 301-278-2946 SMART CONTRACT PREPARATION EXPEDITER FREZELL T LTCOL HUMAN ENGINEERING LAB 301-278-5998

Research Directory for Manpower, Personnel, Training, and Human Factors.

DTIC Science & Technology

1991-01-01

Enhance Automatic Recognition of Speech in Noisy, Highly Stressful Environments Cofod R* Lica Systems Inc 703-359-0996 Smart Contract Preparation...Lab 301-278-2946 Smart Contract Preparation Expediter Frezell T LTCOL Human Engineering Lab 301-278-5998 Impulse Noise Hazard Information Processing R&D

Meta-analysis of the correlation between Helicobacter pylori infection and autoimmune thyroid diseases

PubMed Central

Zhang, Chengfei; Wang, Tieshan; Guo, Xuan; Wu, Lili; Qin, Lingling; Liu, Tonghua

2017-01-01

Objective This study presents a systematic meta-analysis of the correlation between Helicobacter pylori (H. pylori) infection and autoimmune thyroid diseases (AITD). Materials and Methods Fifteen articles including 3,046 cases were selected (1,716 observational and 1,330 control cases). These data were analyzed using Stata12.0 meta-analysis software. Results H. pylori infection was positively correlated with the occurrence of AITD (OR = 2.25, 95% CI: 1.72–2.93). Infection with H. pylori strains positive for the cytotoxin-associated gene A (CagA) were positively correlated with AITD (OR = 1.99, 95% CI: 1.07–3.70). There was no significant difference between infections detected using enzyme-linked immunosorbent assay (ELISA) and other methods (χ2 = 2.151, p = 0.143). Patients with Grave’s disease (GD) and Hashimoto’s thyroiditis (HT) were more susceptible to H. pylori infection (GD: OR = 2.78, 95% CI: 1.68–4.61; HT: OR = 2.16, 95% CI: 1.44–3.23), while the rate of H. pylori infection did not differ between GD and HT (χ2 = 3.113, p = 0.078). Conclusions H. pylori infection correlated with GD and HT, and the eradication of H. pylori infection could reduce thyroid autoantibodies. PMID:29383192

Primary Phase Field of the Pb-Doped 2223 High-Tc Superconductor in the (Bi, Pb)-Sr-Ca-Cu-O System

PubMed Central

Wong-Ng, W.; Cook, L. P.; Kearsley, A.; Greenwood, W.

1999-01-01

Both liquidus and subsolidus phase equilibrium data are of central importance for applications of high temperature superconductors in the (Bi, Pb)-Sr-Ca-Cu-O system, including material synthesis, melt processing and single crystal growth. The subsolidus equilibria of the 110 K high-Tc Pb-doped 2223 ([Bi, Pb], Sr, Ca, Cu) phase and the location of the primary phase field (crystallization field) have been determined in this study. For the quantitative determination of liquidus data, a wicking technique was developed to capture the melt for quantitative microchemical analysis. A total of 29 five-phase volumes that include the 2223 phase as a component was obtained. The initial melt compositions of these volumes range from a mole fraction of 7.3 % to 28.0 % for Bi, 11.3 % to 27.8 % for Sr, 1.2 % to 19.4 % for Pb, 9.8 % to 30.8 % for Ca, and 17.1 % to 47.0 % for Cu. Based on these data, the crystallization field for the 2223 phase was constructed using the convex hull technique. A section of this “volume” was obtained by holding two components of the composition at the median value, allowing projection on the other three axes to show the extent of the field.

Global Diversity and Distribution of Hantaviruses and Their Hosts.

PubMed

Milholland, Matthew T; Castro-Arellano, Iván; Suzán, Gerardo; Garcia-Peña, Gabriel E; Lee, Thomas E; Rohde, Rodney E; Alonso Aguirre, A; Mills, James N

2018-04-30

Rodents represent 42% of the world's mammalian biodiversity encompassing 2,277 species populating every continent (except Antarctica) and are reservoir hosts for a wide diversity of disease agents. Thus, knowing the identity, diversity, host-pathogen relationships, and geographic distribution of rodent-borne zoonotic pathogens, is essential for predicting and mitigating zoonotic disease outbreaks. Hantaviruses are hosted by numerous rodent reservoirs. However, the diversity of rodents harboring hantaviruses is likely unknown because research is biased toward specific reservoir hosts and viruses. An up-to-date, systematic review covering all known rodent hosts is lacking. Herein, we document gaps in our knowledge of the diversity and distribution of rodent species that host hantaviruses. Of the currently recognized 681 cricetid, 730 murid, 61 nesomyid, and 278 sciurid species, we determined that 11.3, 2.1, 1.6, and 1.1%, respectively, have known associations with hantaviruses. The diversity of hantaviruses hosted by rodents and their distribution among host species supports a reassessment of the paradigm that each virus is associated with a single-host species. We examine these host-virus associations on a global taxonomic and geographical scale with emphasis on the rodent host diversity and distribution. Previous reviews have been centered on the viruses and not the mammalian hosts. Thus, we provide a perspective not previously addressed.

Certification of Safety-Critical Software Under DO-178C and DO-278A

NASA Technical Reports Server (NTRS)

Jacklin, Stephen A.

2012-01-01

The RTCA has recently released DO-178C and DO-278A as new certification guidance for the production of airborne and ground-based air traffic management software, respectively. Additionally, RTCA special committee SC-205 has also produced, at the same time, five other companion documents. These documents are RTCA DO-248C, DO-330, DO-331, DO- 332, and DO-333. These supplements address frequently asked questions about software certification, provide guidance on tool qualification requirements, and illustrate the modifications recommended to DO-178C when using model-based software design, object oriented programming, and formal methods. The objective of this paper is to first explain the relationship of DO-178C to the former DO-178B in order to give those familiar with DO- 178B an indication of what has been changed and what has not been changed. With this background, the relationship of DO-178C and DO-278 to the new DO-278A document for ground-based software development is shown. Last, an overview of the new guidance contained in the tool qualification document and the three new supplements to DO-178C and DO-278A is presented. For those unfamiliar with DO-178B, this paper serves to provide an entry point to this new certification guidance for airborne and ground-based CNS/ATM software certification.

50 CFR 622.278 - Commercial trip limits.

Code of Federal Regulations, 2014 CFR

2014-10-01

... ADMINISTRATION, DEPARTMENT OF COMMERCE FISHERIES OF THE CARIBBEAN, GULF OF MEXICO, AND SOUTH ATLANTIC Dolphin and Wahoo Fishery Off the Atlantic States § 622.278 Commercial trip limits. Commercial trip limits are... in this section with any trip or possession limit applicable to state waters. A species subject to a...

50 CFR 622.278 - Commercial trip limits.

Code of Federal Regulations, 2013 CFR

2013-10-01

... ADMINISTRATION, DEPARTMENT OF COMMERCE FISHERIES OF THE CARIBBEAN, GULF OF MEXICO, AND SOUTH ATLANTIC Dolphin and Wahoo Fishery Off the Atlantic States § 622.278 Commercial trip limits. Commercial trip limits are... in this section with any trip or possession limit applicable to state waters. A species subject to a...

75 FR 13287 - Proposed Collection; Comment Request for an Unmodified SF 278 Executive Branch Personnel Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-19

... OFFICE OF GOVERNMENT ETHICS Proposed Collection; Comment Request for an Unmodified SF 278 Executive Branch Personnel Public Financial Disclosure Report AGENCY: Office of Government Ethics (OGE.../Courier: Office of Government Ethics, Suite 500, 1201 New York Avenue, NW., Washington, DC 20005-3917...

7 CFR 278.9 - Implementation of amendments relating to the participation of retail food stores, wholesale food...

Code of Federal Regulations, 2013 CFR

2013-01-01

... participation of retail food stores, wholesale food concerns and insured financial institutions. 278.9 Section..., DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM PARTICIPATION OF RETAIL FOOD STORES... the participation of retail food stores, wholesale food concerns and insured financial institutions...

7 CFR 278.9 - Implementation of amendments relating to the participation of retail food stores, wholesale food...

Code of Federal Regulations, 2011 CFR

2011-01-01

... participation of retail food stores, wholesale food concerns and insured financial institutions. 278.9 Section..., DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM PARTICIPATION OF RETAIL FOOD STORES... the participation of retail food stores, wholesale food concerns and insured financial institutions...

7 CFR 278.9 - Implementation of amendments relating to the participation of retail food stores, wholesale food...

Code of Federal Regulations, 2014 CFR

2014-01-01

... participation of retail food stores, wholesale food concerns and insured financial institutions. 278.9 Section..., DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM PARTICIPATION OF RETAIL FOOD STORES... the participation of retail food stores, wholesale food concerns and insured financial institutions...

7 CFR 278.9 - Implementation of amendments relating to the participation of retail food stores, wholesale food...

Code of Federal Regulations, 2012 CFR

2012-01-01

... participation of retail food stores, wholesale food concerns and insured financial institutions. 278.9 Section..., DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM PARTICIPATION OF RETAIL FOOD STORES... the participation of retail food stores, wholesale food concerns and insured financial institutions...

Whitewater-Baldy Fire

Atmospheric Science Data Center

2015-03-05

... June 12, 2012, it had burned a total of 278,708 acres (1,128 square kilometers), making it the largest wildfire on record in New Mexico. ... June 12, 2012, it had burned a total of 278,708 acres (1,128 square kilometers), making it the largest wildfire on record in New Mexico. The ...

Trace element geochemistry of Manilkara zapota (L.) P. Royen, fruit from winder, Balochistan, Pakistan in perspective of medical geology.

PubMed

Hamza, Salma; Naseem, Shahid; Bashir, Erum; Rizwani, Ghazala H; Hina, Bushra

2013-07-01

An integrated study of rocks, soils and fruits of Manilkara zapota (L.) (Sapotaceae) of Winder area have been carried out to elaborate trace elements relationship between them. The igneous rocks of the study area have elevated amount of certain trace elements, upon weathering these elements are concentrated in the soil of the area. The trace elements concentration in the soil were found in the range of 0.8-197 for Fe, 1.23-140 for Mn, 0.03-16.7 for Zn, 0.07-9.8 for Cr, 0.05-2.0 for Co, 0.52-13.3 for Ni, 0.03-8.8 for Cu, 0.08-10.55 for Pb and 0.13-1.8μg/g for Cd. The distribution pattern of elements in the rocks and soils reflected genetic affiliation. Promising elements of edible part of the fruit were Fe (14.17), Mn (1.49), Cr (2.96), Ni (1.13), Co (0.92), Cu (1.70) and Zn (1.02μg/g). The concentration of these elements in the fruits is above the optimum level of recommended dietary intake, probably due to this, disorder in the human health is suspected in the inhabitants of the area.

Quantifying the effects of soil temperature, moisture and sterilization on elemental mercury formation in boreal soils.

PubMed

Pannu, Ravinder; Siciliano, Steven D; O'Driscoll, Nelson J

2014-10-01

Soils are a source of elemental mercury (Hg(0)) to the atmosphere, however the effects of soil temperature and moisture on Hg(0) formation is not well defined. This research quantifies the effect of varying soil temperature (278-303 K), moisture (15-80% water filled pore space (WFPS)) and sterilization on the kinetics of Hg(0) formation in forested soils of Nova Scotia, Canada. Both, the logarithm of cumulative mass of Hg(0) formed in soils and the reduction rate constants (k values) increased with temperature and moisture respectively. Sterilizing soils significantly (p < 0.05, n = 10) decreased the percent of total Hg reduced to Hg(0). We describe the fundamentals of Hg(0) formation in soils and our results highlight two key processes: (i) a fast abiotic process that peaks at 45% WFPS and depletes a small pool of Hg(0) and; (ii) a slower, rate limiting biotic process that generates a large pool of reducible Hg(II). Copyright © 2014 Elsevier Ltd. All rights reserved.

New Fission Fragment Distributions and r-Process Origin of the Rare-Earth Elements

NASA Astrophysics Data System (ADS)

Goriely, S.; Sida, J.-L.; Lemaître, J.-F.; Panebianco, S.; Dubray, N.; Hilaire, S.; Bauswein, A.; Janka, H.-T.

2013-12-01

Neutron star (NS) merger ejecta offer a viable site for the production of heavy r-process elements with nuclear mass numbers A≳140. The crucial role of fission recycling is responsible for the robustness of this site against many astrophysical uncertainties, but calculations sensitively depend on nuclear physics. In particular, the fission fragment yields determine the creation of 110≲A≲170 nuclei. Here, we apply a new scission-point model, called SPY, to derive the fission fragment distribution (FFD) of all relevant neutron-rich, fissioning nuclei. The model predicts a doubly asymmetric FFD in the abundant A≃278 mass region that is responsible for the final recycling of the fissioning material. Using ejecta conditions based on relativistic NS merger calculations, we show that this specific FFD leads to a production of the A≃165 rare-earth peak that is nicely compatible with the abundance patterns in the Sun and metal-poor stars. This new finding further strengthens the case of NS mergers as possible dominant origin of r nuclei with A≳140.

25 CFR 700.511 - Statements of employment and financial interests.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Disclosure Reports (SF-278) to the Deputy Ethics Counselor of the Department of Interior, according to... of the Senior Executive Service shall be resolved by the Ethics Officer of the Department of the Interior. (2) The Designated Agency Ethics Official shall submit SF-278 to the Office of Government Ethics...

7 CFR 278.7 - Determination and disposition of claims-retail food stores and wholesale food concerns.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 4 2011-01-01 2011-01-01 false Determination and disposition of claims-retail food... PROGRAM PARTICIPATION OF RETAIL FOOD STORES, WHOLESALE FOOD CONCERNS AND INSURED FINANCIAL INSTITUTIONS § 278.7 Determination and disposition of claims—retail food stores and wholesale food concerns. (a...

7 CFR 278.7 - Determination and disposition of claims-retail food stores and wholesale food concerns.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 4 2013-01-01 2013-01-01 false Determination and disposition of claims-retail food... PROGRAM PARTICIPATION OF RETAIL FOOD STORES, WHOLESALE FOOD CONCERNS AND INSURED FINANCIAL INSTITUTIONS § 278.7 Determination and disposition of claims—retail food stores and wholesale food concerns. (a...

7 CFR 278.7 - Determination and disposition of claims-retail food stores and wholesale food concerns.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 4 2014-01-01 2014-01-01 false Determination and disposition of claims-retail food... PROGRAM PARTICIPATION OF RETAIL FOOD STORES, WHOLESALE FOOD CONCERNS AND INSURED FINANCIAL INSTITUTIONS § 278.7 Determination and disposition of claims—retail food stores and wholesale food concerns. (a...

7 CFR 278.7 - Determination and disposition of claims-retail food stores and wholesale food concerns.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 4 2012-01-01 2012-01-01 false Determination and disposition of claims-retail food... PROGRAM PARTICIPATION OF RETAIL FOOD STORES, WHOLESALE FOOD CONCERNS AND INSURED FINANCIAL INSTITUTIONS § 278.7 Determination and disposition of claims—retail food stores and wholesale food concerns. (a...

Long-term use of biosolids as organic fertilizers in agricultural soils: potentially toxic elements occurrence and mobility.

PubMed

Marguí, E; Iglesias, M; Camps, F; Sala, L; Hidalgo, M

2016-03-01

The presence of potentially toxic elements (PTEs) may hinder a more widespread application of biosolids in agriculture. At present, the European Directive 86/278/CEE limit the total concentrations of seven metals (Cu, Cr, Ni, Pb, Zn, Cd and Hg) in agricultural soils and in sewage sludges used as fertilizers but it has not taken into consideration the potential impacts of other emerging micropollutants that may be present in the biosolids as well as their mobility. The aim of this study was to evaluate the accumulation and mobility of 13 elements (including regulated metals and other inorganic species) in agricultural soils repeatedly amended with biosolids for 15 years. Firstly, three digestions programs using different acid mixtures were tested to evaluate the most accurate and efficient method for analysis of soil and sludge. Results demonstrated that sewage sludge application increased concentrations of Pb and Hg in soil, but values did not exceed the quality standard established by legislation. In addition, other elements (As, Co, Sb, Ag, Se and Mn) that at present are not regulated by the Spanish and European directives were identified in the sewage sludge, and significant differences were found between Ag content in soils amended with biosolids in comparison with control soils. This fact can be related to the increasing use of silver nanoparticles in consumer products due to their antibacterial properties. Results from the leaching tests show up that, in general, the mobility degree for both regulated and non-regulated elements in soils amended with biosolids was quite low (<10 %).

Molecular Evolution of a Klebsiella pneumoniae ST278 Isolate Harboring blaNDM-7 and Involved in Nosocomial Transmission.

PubMed

Lynch, Tarah; Chen, Liang; Peirano, Gisele; Gregson, Dan B; Church, Deirdre L; Conly, John; Kreiswirth, Barry N; Pitout, Johann D

2016-09-01

During 2013, ST278 Klebsiella pneumoniae with blaNDM-7 was isolated from the urine (KpN01) and rectum (KpN02) of a patient in Calgary, Canada. The same strain (KpN04) was subsequently isolated from another patient in the same unit. Interestingly, a carbapenem-susceptible K. pneumoniae ST278 (KpN06) was obtained 1 month later from the blood of the second patient. Next-generation sequencing (NGS) revealed that the loss of carbapenem-resistance in KpN06 was due to a 5-kb deletion on the blaNDM-7-harboring IncX3 plasmid. In addition, an IncFIB plasmid in KpN06 had a 27-kb deletion that removed genes encoding for heavy metal resistance. Phylogenetic analysis showed that the K. pneumoniae ST278 from patient 2 was likely a descendant of KpN02 and that KpN06 was a close progenitor of an environmental ST278. It is unclear whether KpN06 lost the blaNDM-7 gene in vivo. This study detailed the remarkable plasticity and speed of evolutionary changes in multidrug-resistant K. pneumoniae, demonstrating the highly recombinant nature of this species. It also highlights the ability of NGS to clarify molecular microevolutionary events within antibiotic-resistant organisms. © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.

Evaluation of the Impact of Kerojet (trademark) Aquarius Water Scavenger Additive on the Thermal Stability of Jet A Fuels

DTIC Science & Technology

2014-12-01

113 Figure 64 - Elemental Analysis, Typical TMS Post - Test , Post Carbon Burn-off, Hexane rinsed ............ 114 Figure 65 – SEM (20X...Agency’s Wright-Patterson Aerospace Fuels Laboratory AFRL Air Force Research Laboratory AFTSTU Aviation Fuel Thermal Stability Test Unit ARSFSS Advanced...Approved for public release; distribution unlimited. For all ARSFSS testing , SV hysteresis is measure pre- and post - test and is defined by relating

Analytical Predictions of Thermal Stress in the Stardust PICA Heatshield Under Reentry Flight Conditions

NASA Technical Reports Server (NTRS)

Squire, Thomas; Milos, Frank; Agrawal, Parul

2009-01-01

We performed finite element analyses on a model of the Phenolic Impregnated Carbon Ablator (PICA) heatshield from the Stardust sample return capsule (SRC) to predict the thermal stresses in the PICA material during reentry. The heatshield on the Stardust SRC was a 0.83 m sphere cone, fabricated from a single piece of 5.82 cm-thick PICA. The heatshield performed successfully during Earth reentry of the SRC in January 2006. Material response analyses of the full, axisymmetric PICA heatshield were run using the Two-Dimensional Implicit Ablation, Pyrolysis, and Thermal Response Program (TITAN). Peak surface temperatures were predicted to be 3385K, while the temperature at the PICA backface remained at the estimated initial cold-soak temperature of 278K. Surface recession and temperature distribution results from TITAN, at several points in the reentry trajectory, were mapped onto an axisymmetric finite element model of the heatshield. We used the finite element model to predict the thermal stresses in the PICA from differential thermal expansion. The predicted peak compressive stress in the PICA heatshield was 1.38 MPa. Although this level of stress exceeded the chosen design limit for compressive stresses in PICA tiles for the design of the Orion crew exploration vehicle heatshield, the Stardust heatshield exhibited no obvious mechanical failures from thermal stress. The analyses of the Stardust heatshield were used to assess and adjust the level of conservatism in the finite element analyses in support of the Orion heatshield design.

278. Photocopy of drawing (1978 structural electrical drawing by the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

278. Photocopy of drawing (1978 structural electrical drawing by the Space and Missile Test Center, VAFB, USAF) DETAILS, SECTION, AND ELECTRICAL PLAN FOR THE TIROS AND NOAA THEODOLITE STATION, SLC-3E, SHEET 4 OF 4 - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 East, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

7 CFR 278.6 - Disqualification of retail food stores and wholesale food concerns, and imposition of civil money...

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 4 2013-01-01 2013-01-01 false Disqualification of retail food stores and wholesale..., DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM PARTICIPATION OF RETAIL FOOD STORES, WHOLESALE FOOD CONCERNS AND INSURED FINANCIAL INSTITUTIONS § 278.6 Disqualification of retail food stores...

76 FR 73761 - Notice to Rescind the Notice of Intent to Develop the Environmental Impact Statement: Kings...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-29

... an Environmental Impact Statement (EIS) for the proposed project involving approximately 1.5 miles of the Brooklyn- Queens Expressway (BQE), Interstate 278 (I-278) in Kings County, New York (Project..., from Sands Street on the east to Atlantic Avenue on the west. The purpose of the original Project was...

Thermophysical Properties of Matter - The TPRC Data Series. Volume 4. Specific Heat - Metallic Elements and Alloys

DTIC Science & Technology

1971-01-01

alloys— sodium — sodium alloya— solder—carbon ateels—chromium steels—silicon steels—tantalum—tantalum alloys—terbium—thallium—thallium alloys—thorium...Praseodymium 45 Rhenium 46 Rhodium 47 Rubidium 48 Ruthenium 4» Samarium 50 Scandium 51 Selenium 52 Silicon 5:i Silver 54 Sodium 55 Strontium 56...Potassium ♦ Sodium 111 Sodium * Potassium 112 Tantalum ♦ Tungsten 113 Thallium + Lead, PbTl| 114 Tin ♦ Bismuth 115 Tin ♦ Indium 116 Tin+ Lead 117

Minnesota Water Allocation Law. Volume 1. Commentary on and Abstracts of Treaties, Legislation and Rules.

DTIC Science & Technology

1987-09-01

If applicable) 8c. ADDRESS(City, State, and ZIP Code) 10. SOURCE OF FUNDING NUMBERS ELEMENT NO. NO. NO ACCESSION NO .T 11 TITLE (Include Security...Indians 1-13 Domestic Water Supply on Reservations 1-14 Ground water sources 1-16 Surface water sources 1-16 Commentary on Indian Water Resources 1-17...General’s Office - St. Paul, Minnesota 4 DATA COLLECTION AND REPORT ORGANIZATION Data collected for these volumes result from three primary sources

Effect of Outside Combustion Air on Gas Furnace Efficiency.

DTIC Science & Technology

1981-10-15

Support Agency REPORT FESA-TS-2104 EFFECT OF OUTSIDE COMBUSTION AIR ON GAS FURNACE EFFICIENCY THOMAS E. BRISBANE Q KATHLEEN L. HANCOCK u JOHNS - MANVILLE SALES...and Dilution Air With No Furnace Setback. 93 AO-A113 4~84 . JOHNS - MANVILLE SALES CORP DENVER CO RESEARCH AND OEV--ETC F/6 13/ 1 EFFECT OF OUTSIDE...NUMBER(S) Thomas E. Brisbane, Kathleen L. Hancock DAAK 70-78-D-0002 9. PERFORMING ORGANIZATION NAME AND ADDRESS 1O. PROGRAM ELEMENT. PR.;ECT, TASK Johns

STS-92 Mission Specialist Wakata gets ready to drive the M-113

NASA Technical Reports Server (NTRS)

2000-01-01

Getting ready to take his turn at the wheel of the M-113 is Mission Specialist Koichi Wakata of Japan. Behind him can be seen Mission Specialists Bill McArthur (left) and Leroy Chiao (right), who wait their turns. Learning to drive the armored vehicle is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

STS-92 Mission Specialist Wakata takes his turn driving the M-113

NASA Technical Reports Server (NTRS)

2000-01-01

With Capt. George Hoggard, trainer with the KSC Fire Department, riding on top, Mission Specialist Koichi Wakata of Japan practices driving the M-113, part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. Riding in the back (on the left) are other crew members, waiting their turn to drive. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

STS-92 Mission Specialist McArthur is ready to take his turn driving the M-113

NASA Technical Reports Server (NTRS)

2000-01-01

STS-92 Mission Specialist Bill McArthur gets ready to take his turn at driving the M-113, part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. Behind him (left) is Mission Specialist Jeff Wisoff, waiting his turn to drive along with other unidentified crew members. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

STS-92 Mission Specialist Wakata completes his turn driving the M-113

NASA Technical Reports Server (NTRS)

2000-01-01

STS-92 Mission Specialist Koichi Wakata of Japan signals a successful driving lesson on the M-113 he is in. Capt. George Hoggard, trainer with the KSC Fire Department, sits on top. Behind Wakata are Commander Brian Duffy (left) and Leroy Chiao (right), waiting their turns. The practice drive is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

Publications - GMC 278 | Alaska Division of Geological & Geophysical

Science.gov Websites

DGGS GMC 278 Publication Details Title: High pressure methane adsorption analyses for coal samples of the Matanuska Valley coal-bed methane AK 94-CBM-1 hole as follows: Seam #1, Seam #6, Seam #9, and Seam , High pressure methane adsorption analyses for coal samples of the Matanuska Valley coal-bed methane AK

26 CFR 1.278-1 - Capital expenditures incurred in planting and developing citrus and almond groves.

Code of Federal Regulations, 2010 CFR

2010-04-01

...) Except as provided in subparagraph (2)(iii) of this paragraph and paragraph (b) of this section, there... taxable year beginning with the taxable year in which the trees were planted. For purposes of section 278... one or more trees of the rue family, often thorny and bearing large fruit with hard, usually thick...

Linkage studies on chromosome 22 in familial schizophrenia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vallada, H.P.; Gill, M.; Sham, P.

1995-04-24

As part of a systematic search for a major genetic locus for schizophrenia we have examined chromosome 22 using 14 highly polymorphic markers in 23 disease pedigrees. The markers were distributed at an average distance of 6.6 cM, covering 70-80% of the chromosome. We analyzed the data by the lod score method using five plausible genetic models ranging from dominant to recessive, after testing the power of our sample under the same genetic parameters. The most positive lod score found was 1.51 under a recessive model for the marker D22S278, which is insufficient to conclude linkage. However, an excess ofmore » shared alleles in affected siblings (P < .01) was found for both D22S278 and D22S283. For D22S278, the A statistic was equal to the lod score (1.51) and therefore did not provide additional evidence for linkage allowing for heterogeneity, but the Liang statistic was more significant (P = .002). Our results suggest the possibility that the region around D22S278 and D22S283 contains a gene which contributes to the etiology of schizophrenia. 60 refs., 1 fig., 5 tabs.« less

Characterizing suspended sediments from the Piracicaba River Basin by means of k0-INAA

NASA Astrophysics Data System (ADS)

França, E. J.; Fernandes, E. A. N.; Cavalca, I. P. O.; Fonseca, F. Y.; Camilli, L.; Rodrigues, V. S.; Bardini Junior, C.; Ferreira, J. R.; Bacchi, M. A.

2010-10-01

The inorganic chemical characterization of suspended sediments is of utmost relevance for the knowledge of the dynamics and movement of chemical elements in the aquatic and wet ecosystems. Despite the complexity of the effective design for studying this ecological compartment, this work has tested a procedure for analyzing suspended sediments by instrumental neutron activation analysis, k0 method ( k0-INAA). The chemical elements As, Ba, Br, Ca, Ce, Co, Cr, Cs, Eu, Fe, Hf, Hg, K, La, Mo, Na, Ni, Rb, Sb, Sc, Se, Sm, Sr, Ta, Tb, Th, Yb and Zn were quantified in the suspended sediment compartment by means of k0-INAA. When compared with World Average for rivers, high mass fractions of Fe (222,900 mg/kg), Ba (4990 mg/kg), Zn (1350 mg/kg), Cr (646 mg/kg), Co (74.5 mg/kg), Br (113 mg/kg) and Mo (31.9 mg/kg) were quantified in suspended sediments from the Piracicaba River, the Piracicamirim Stream and the Marins Stream. Results of the principal component analysis for standardized chemical element mass fractions indicated an intricate correlation among chemical elements evaluated, as a response of the contribution of natural and anthropogenic sources of chemical elements for ecosystems.

Measurement of concentrations of whole blood levels of choline, betaine, and dimethylglycine and their relations to plasma levels.

PubMed

Awwad, Hussain Mohamad; Kirsch, Susanne H; Geisel, Juergen; Obeid, Rima

2014-04-15

We aimed at developing a method for the measurement of choline and its metabolites in whole blood (WB). After an extraction step, quantification of choline, betaine, and dimethylglycine (DMG) was performed using ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS). Plasma and WB metabolites were evaluated in a group of 61 elderly people. The calibration curves were linear (r(2)>0.997) for all compounds. The inter- and intra-assay coefficients of variation for all analytes were <10%. The recoveries were >90% and the relative matrix effect were ≤4.0%. The median concentrations of choline, betaine, and DMG were 11.3, 27.8, and 5.9μmol/L in plasma and 66.6, 165, and 13.7μmol/L in WB, respectively. There were positive correlations between WB and plasma markers; for choline (r=0.42), betaine (r=0.61), and DMG (r=0.56) (all p≤0.001). The concentrations of betaine in WB and plasma were significantly higher in men than in women. The concentrations of WB choline and DMG did not differ significantly according to sex. In conclusion, we have established a reliable method for measuring choline metabolites in WB. The concentrations of WB choline, betaine, and DMG seem to reflect intracellular concentrations of these metabolites. Copyright © 2014 Elsevier B.V. All rights reserved.

Analysis of sentinel node positivity in primary cutaneous melanoma: an 8-year single institution experience.

PubMed

Joyce, K M; McInerney, N M; Piggott, R P; Martin, F; Jones, D M; Hussey, A J; Kerin, M J; Kelly, J L; Regan, P J

2017-11-01

Sentinel lymph node biopsy (SLNB) is a standard method for determining the pathologic status of the regional lymph nodes. The aim of our study was to determine the incidence and clinicopathologic factors predictive of SLN positivity, and to evaluate the prognostic importance of SLNB in patients with cutaneous melanoma. We performed a retrospective analysis of a prospectively maintained database of all patients who underwent SLNB for primary melanoma at our institution from 2005 to 2012. Statistical analysis was performed using χ 2 and Fischer exact test. In total, 318 patients underwent SLNB, of which 65 were for thin melanoma (≤1 mm). There were 36 positive SLNB, 278 negative SLNB and in four cases the SLN was not located. The incidence rate for SLNB was 11.3% overall and 1.5% in thin melanomas alone. Statistical analysis identified Breslow thickness >1 mm (P = 0.006), Clark level ≥ IV (P = 0.004) and age <75 years (P = 0.035) as the strongest predictors of SLN positivity. Our overall false negativity rate was 20% (9/45) with one case of false-negative SLNB in thin melanomas. Breslow thickness of the primary tumour remains the strongest predictor of SLN positivity. Our findings point to a possible limited role for SLNB in thin melanoma due to its low positivity rate, associated false-negative rate and related morbidity.

Dual-task gait differences in female and male adolescents following sport-related concussion.

PubMed

Howell, David R; Stracciolini, Andrea; Geminiani, Ellen; Meehan, William P

2017-05-01

Concussion may affect females and males differentially. Identification of gender-related differences after concussion, therefore, may help clinicians with individualized evaluations. We examined potential differences in dual-task gait between females and males after concussion. Thirty-five participants diagnosed with a concussion (49% female, mean age=15.0±2.1 years, 7.5±3.0 days post-injury) and 51 controls (51% female, mean age=14.4±2.1 years) completed a symptom inventory and single/dual-task gait assessment. The primary outcome variable, the dual-task cost, was calculated as the percent change between single-task and dual-task conditions to account for individual differences in spatio-temporal gait variables. No significant differences in symptom severity measured by the post-concussion symptom scale were observed between females (32.0±18.0) and males (27.8±18.2). Compared with males, adolescent females walked with significantly decreased cadence dual-task costs after concussion (-19.7%±10.0% vs. -11.3%±9.2%, p=0.007) when adjusted for age, height, and prior concussion history. No significant differences were found between female and male control groups on other dual-task cost gait measures. Females and males with concussion also walked with significantly shorter stride lengths than controls during single-task (females: 1.13±0.11m vs. 1.26±0.11m, p=0.001; males: 1.14±0.14m vs. 1.22±0.15m, p=0.04) and dual-task gait (females: 0.99±0.10m vs. 1.10±0.11m, p=0.001; males: 1.00±0.13m vs. 1.08±0.14m, p=0.04). Females demonstrated a significantly greater amount of cadence change between single-task and dual-task gait than males after a sport-related concussion. Thus, differential alterations may exist during gait among those with a concussion; gender may be one prominent factor affecting dual-task gait. Copyright © 2017 Elsevier B.V. All rights reserved.

Responses of trace elements to aerobic maximal exercise in elite sportsmen.

PubMed

Otag, Aynur; Hazar, Muhsin; Otag, Ilhan; Gürkan, Alper Cenk; Okan, Ilyas

2014-02-21

Trace elements are chemical elements needed in minute quantities for the proper growth, development, and physiology of the organism. In biochemistry, a trace element is also referred to as a micronutrient. Trace elements, such as nickel, cadmium, aluminum, silver, chromium, molybdenum, germanium, tin, titanium, tungsten, scandium, are found naturally in the environment and human exposure derives from a variety of sources, including air, drinking water and food. The Purpose of this study was investigated the effect of aerobic maximal intensity endurance exercise on serum trace elements as well-trained individuals of 28 wrestlers (age (year) 19.64±1.13, weight (Kg) 70.07 ± 15.69, height (cm) 176.97 ± 6.69) during and after a 2000 meter Ergometer test protocol was used to perform aerobic (75 %) maximal endurance exercise. Trace element serum levels were analyzed from blood samples taken before, immediately after and one hour after the exercise. While an increase was detected in Chromium (Cr), Nickel (Ni), Molybdenum (Mo) and Titanium (Ti) serum levels immediately after the exercise, a decrease was detected in Aluminum (Al), Scandium (Sc) and Tungsten (W) serum levels. Except for aluminum, the trace elements we worked on showed statistically meaningful responses (P < 0.05 and P < 0.001). According to the responses of trace elements to the exercise showed us the selection and application of the convenient sport is important not only in terms of sportsman performance but also in terms of future healthy life plans and clinically.

Betaine supplementation is less effective than methionine restriction in correcting phenotypes of CBS deficient mice.

PubMed

Gupta, Sapna; Wang, Liqun; Kruger, Warren D

2016-01-01

Cystathionine beta synthase (CBS) deficiency is a recessive inborn error of metabolism characterized by elevated serum total homocysteine (tHcy). Betaine supplementation, which can lower tHcy by stimulating homocysteine remethylation to methionine, is often given to CBS deficient patients in combination with other treatments such as methionine restriction and supplemental B-vitamins. However, the effectiveness of betaine supplementation by itself in the treatment of CBS deficiency has not been well explored. Here, we have examined the effect of a betaine supplemented diet on the Tg-I278T Cbs (-/-) mouse model of CBS deficiency and compared its effectiveness to our previously published data using a methionine restricted diet. Tg-I278T Cbs (-/-) mice on betaine, from the time of weaning until for 240 days of age, had a 40 % decrease in mean tHcy level and a 137 % increase in serum methionine levels. Betaine-treated Tg-I278T Cbs (-/-) mice also exhibited increased levels of betaine-dependent homocysteine methyl transferase (BHMT), increased levels of the lipogenic enzyme stearoyl-coenzyme A desaturase (SCD-1), and increased lipid droplet accumulation in the liver. Betaine supplementation largely reversed the hair loss phenotype in Tg-I278T Cbs (-/-) animals, but was far less effective than methionine restriction in reversing the weight-loss, fat-loss, and osteoporosis phenotypes. Surprisingly, betaine supplementation had several negative effects in control Tg-I278T Cbs (+/-) mice including decreased weight gain, lean mass, and bone mineral density. Our findings indicate that while betaine supplementation does have some beneficial effects, it is not as effective as methionine restriction for reversing the phenotypes associated with severe CBS deficiency in mice.

Identification of a Novel EF-Loop in the N-terminus of TRPM2 Channel Involved in Calcium Sensitivity

PubMed Central

Luo, Yuhuan; Yu, Xiafei; Ma, Cheng; Luo, Jianhong; Yang, Wei

2018-01-01

As an oxidative stress sensor, transient receptor potential melastatin 2 (TRPM2) channel is involved in many physiological and pathological processes including warmth sensing, ischemia injury, inflammatory diseases and diabetes. Intracellular calcium is critical for TRPM2 channel activation and the IQ-like motif in the N-terminus has been shown to be important by mediating calmodulin binding. Sequence analysis predicted two potential EF-loops in the N-terminus of TRPM2. Site-directed mutagenesis combining with functional assay showed that substitution with alanine of several residues, most of which are conserved in the typical EF-loop, including D267, D278, D288, and E298 dramatically reduced TRPM2 channel currents. By further changing the charges or side chain length of these conserved residues, our results indicate that the negative charge of D267 and the side chain length of D278 are critical for calcium-induced TRPM2 channel activation. G272I mutation also dramatically reduced the channel currents, suggesting that this site is critical for calcium-induced TRPM2 channel activation. Furthermore, D267A mutant dramatically reduced the currents induced by calcium alone compared with that by ADPR, indicating that D267 residue in D267–D278 motif is the most important site for calcium sensitivity of TRPM2. In addition, inside-out recordings showed that mutations at D267, G272, D278, and E298 had no effect on single-channel conductance. Taken together, our data indicate that D267–D278 motif in the N-terminus as a novel EF-loop is critical for calcium-induced TRPM2 channel activation.

Levels of Essential Elements in Different Medicinal Plants Determined by Using Inductively Coupled Plasma Mass Spectrometry

PubMed Central

2018-01-01

The objective of this study was to investigate the content of essential elements in medicinal plants in the Kingdom of Saudi Arabia (KSA). Five different medical plants (mahareeb (Cymbopogon schoenanthus), sheeh (Artemisia vulgaris), harjal (Cynanchum argel delile), nabipoot (Equisetum arvense), and cafmariam (Vitex agnus-castus)) were collected from Madina city in the KSA. Five elements Fe, Mn, Zn, Cu, and Se were determined by using inductively coupled plasma mass spectrometry (ICP-MS). Fe levels were the highest and Se levels were the lowest in all plants. The range levels of all elements in all plants were as follows: Fe 193.4–1757.9, Mn 23.6–143.7, Zn 15.4–32.7, Se 0.13–0.92, and Cu 11.3–21.8 µg/g. Intakes of essential elements from the medical plants in infusion were calculated: Fe 4.6–13.4, Mn 6.7–123.2, Zn 7.0–42.7, Se 0.14–1.5, and Cu 1.5–5.0 µg/dose. The calculated intakes of essential elements for all plants did not exceed the daily intake set by the World Health Organization (WHO) and European Food Safety Authority (EFSA). These medicinal plants may be useful sources of essential elements, which are vital for health. PMID:29744234

Metro Commuter Exposures to Particulate Air Pollution and PM2.5-Associated Elements in Three Canadian Cities: The Urban Transportation Exposure Study.

PubMed

Van Ryswyk, Keith; Anastasopolos, Angelos T; Evans, Greg; Sun, Liu; Sabaliauskas, Kelly; Kulka, Ryan; Wallace, Lance; Weichenthal, Scott

2017-05-16

System-representative commuter air pollution exposure data were collected for the metro systems of Toronto, Montreal, and Vancouver, Canada. Pollutants measured included PM 2.5 (PM = particulate matter), PM 10 , ultrafine particles, black carbon, and the elemental composition of PM 2.5 . Sampling over three weeks was conducted in summer and winter for each city and covered each system on a daily basis. Mixed-effect linear regression models were used to identify system features related to particulate exposures. Ambient levels of PM 2.5 and its elemental components were compared to those of the metro in each city. A microenvironmental exposure model was used to estimate the contribution of a 70 min metro commute to daily mean exposure to PM 2.5 elemental and mass concentrations. Time spent in the metro was estimated to contribute the majority of daily exposure to several metallic elements of PM 2.5 and 21.2%, 11.3% and 11.5% of daily PM 2.5 exposure in Toronto, Montreal, and Vancouver, respectively. Findings suggest that particle air pollutant levels in Canadian metros are substantially impacted by the systems themselves, are highly enriched in steel-based elements, and can contribute a large portion of PM 2.5 and its elemental components to a metro commuter's daily exposure.

Fine structure of the late Eocene Ir anomaly in marine sediments

NASA Technical Reports Server (NTRS)

Asaro, F.

1991-01-01

The Late Eocene Ir abundance profile in deep sea cores from Ocean Drilling Program Leg 113 Hole 689B on the Maude Rise off of Antarctica was studied with 410 samples continuously in 10 cm increments and measured with the Iridium Coincidence (ICS). The ICS was subsequently modified to measure 13 other elements simultaneously with the Ir. The abundance profiles of these elements were then determined in the Late Eocene Massignano section in central Italy with 250 samples (encompassing roughly 2 million years of accumulation) which were collected about every 5 cm in about 2 cm increments. These studies augmented a previous one (which included many elements) of deep sea cores from Deep Sea Drilling Project Site 592 on the Lord Howe Rise in the Tasman Sea between Australia and New Zealand. In the latter study, 50 samples (encompassing roughly 0.7 million years of accumulation) were collected continuously in 10 cm increments. The results from these studies are discussed.

Extended HSR/CARD domain mediates AIRE binding to DNA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maslovskaja, Julia, E-mail: julia.maslovskaja@ut.ee; Saare, Mario; Liiv, Ingrid

Autoimmune regulator (AIRE) activates the transcription of many genes in an unusual promiscuous and stochastic manner. The mechanism by which AIRE binds to the chromatin and DNA is not fully understood, and the regulatory elements that AIRE target genes possess are not delineated. In the current study, we demonstrate that AIRE activates the expression of transiently transfected luciferase reporters that lack defined promoter regions, as well as intron and poly(A) signal sequences. Our protein-DNA interaction experiments with mutated AIRE reveal that the intact homogeneously staining region/caspase recruitment domain (HSR/CARD) and amino acids R113 and K114 are key elements involved inmore » AIRE binding to DNA. - Highlights: • Promoter and mRNA processing elements are not important for AIRE to activate gene expression from reporter plasmids. • AIRE protein fragment aa 1–138 mediates direct binding to DNA. • Integrity of the HSR/CARD domain is needed for AIRE binding to DNA.« less

Basic distinctions between cold- and hot-fusion reactions in the synthesis of superheavy elements

NASA Astrophysics Data System (ADS)

Nasirov, A. K.; Muminov, A. I.; Giardina, G.; Mandaglio, G.

2014-07-01

Superheavy elements (SHE) of charge number in the range of Z = 106-112 were synthesized in so-called cold-fusion reactions. The smallness of the excitation energy of compound nuclei is the main advantage of cold-fusion reactions. However, the synthesis of SHEs of charge number in the region of Z ≥ 112 is strongly complicated in cold-fusion reactions by a sharp decrease in the cross section of a compound nucleus formation in the entrance channel because of superiority of quasifission in the competition with complete fusion. Two favorable circumstances contributed to the success of the experiments aimed at the synthesis of the Z = 113-118 elements and performed at the Laboratory of Nuclear Reactions at the Joint Institute for Nuclear Research: large cross sections for the production of a compound nucleus, which are characteristic of hot-fusion reactions, and an increase in the fission barrier for nuclei toward the stability island. The factor that complicates the formation of a compound nucleus in cold-fusion reactions is discussed.

Miniaturized force/torque sensor for in vivo measurements of tissue characteristics.

PubMed

Hessinger, M; Pilic, T; Werthschutzky, R; Pott, P P

2016-08-01

This paper presents the development of a surgical instrument to measure interaction forces/torques with organic tissue during operation. The focus is on the design progress of the sensor element, consisting of a spoke wheel deformation element with a diameter of 12 mm and eight inhomogeneous doped piezoresistive silicon strain gauges on an integrated full-bridge assembly with an edge length of 500 μm. The silicon chips are contacted to flex-circuits via flip chip and bonded on the substrate with a single component adhesive. A signal processing board with an 18 bit serial A/D converter is integrated into the sensor. The design concept of the handheld surgical sensor device consists of an instrument coupling, the six-axis sensor, a wireless communication interface and battery. The nominal force of the sensing element is 10 N and the nominal torque is 1 N-m in all spatial directions. A first characterization of the force sensor results in a maximal systematic error of 4.92 % and random error of 1.13 %.

Effectiveness of a Risk Screener in Identifying Hepatitis C Virus in a Primary Care Setting

PubMed Central

Litwin, Alain H.; Smith, Bryce D.; Koppelman, Elisa A.; McKee, M. Diane; Christiansen, Cindy L.; Gifford, Allen L.; Weinbaum, Cindy M.; Southern, William N.

2012-01-01

Objectives. We evaluated an intervention designed to identify patients at risk for hepatitis C virus (HCV) through a risk screener used by primary care providers. Methods. A clinical reminder sticker prompted physicians at 3 urban clinics to screen patients for 12 risk factors and order HCV testing if any risks were present. Risk factor data were collected from the sticker; demographic and testing data were extracted from electronic medical records. We used the t test, χ2 test, and rank-sum test to compare patients who had and had not been screened and developed an analytic model to identify the incremental value of each element of the screener. Results. Among screened patients, 27.8% (n = 902) were identified as having at least 1 risk factor. Of screened patients with risk factors, 55.4% (n = 500) were tested for HCV. Our analysis showed that 7 elements (injection drug use, intranasal drug use, elevated alanine aminotransferase, transfusions before 1992, ≥ 20 lifetime sex partners, maternal HCV, existing liver disease) accounted for all HCV infections identified. Conclusions. A brief risk screener with a paper-based clinical reminder was effective in increasing HCV testing in a primary care setting. PMID:22994166

Isolation and Characterization of Canthaxanthin Biosynthesis Genes from the Photosynthetic Bacterium Bradyrhizobium sp. Strain ORS278

PubMed Central

Hannibal, Laure; Lorquin, Jean; D'Ortoli, Nicolas Angles; Garcia, Nelly; Chaintreuil, Clemence; Masson-Boivin, Catherine; Dreyfus, Bernard; Giraud, Eric

2000-01-01

A carotenoid biosynthesis gene cluster involved in canthaxanthin production was isolated from the photosynthetic Bradyrhizobium sp. strain ORS278. This cluster includes five genes identified as crtE, crtY, crtI, crtB, and crtW that are organized in at least two operons. The functional assignment of each open reading frame was confirmed by complementation studies. PMID:10851005

Development of a Solid Rocket Propellant Nonlinear Constitutive Theory

DTIC Science & Technology

1975-05-01

14 21 29 15 28 27 45 34 44 28 43 22 16 41 lü 40 58 35 57 59 56 23 55 17 54 11 53 36 30 24 18 1? J 6 0.0 0.1 0.2 0.3...Analysis 123 SECTION 6 - TASK IV - FINITE ELEMENT CODE DEMONSTRATION 139 A. Work to be Accomplished 139 B. Original Task IV Effort 139 C. Task IV...Vlscoelastlc Predictions 55 and Fyperimental Data for Sollthane 113 6 Comparison of Linear Vlscoelastlc Predictions 56 and Experimental Data for

Biodegradation of DIMP, Dieldrin, Isodrin, DBCP, and PCPMSO in Rocky Mountain Arsenal Soils. Installation Restoration Program, Environmental Technology Development

DTIC Science & Technology

1989-01-01

Number DAAK- 1 1 -85-D-007 Report Number CETHA-TE-CR-89006 January 1989 Prepared for: COMMANDER, U.S. ARMY TOXIC AND HAZARDOUS MATERIALS AGENCY Aberdeen...UNIT Aberdeen Proving Ground, MD 21010-5401 ELEMENT NO. NO. NO. ACCESSION NO. 1 . TITLE (Include Security Classification) - Biodegradation of DIMP...TYPE OF REPORT 113b. TIME COVERED 114. DATE OF REPORT (Year, Month, Day) 15. PAGE COUNT Final I FROM 1 /87 TO_1/89 1989 January 30 6. SUPPLEMENTARY

GEODYN programmers guide, volume 2, part 1

NASA Technical Reports Server (NTRS)

Mullins, N. E.; Goad, C. C.; Dao, N. C.; Martin, T. V.; Boulware, N. L.; Chin, M. M.

1972-01-01

A guide to the GEODYN Program is presented. The program estimates orbit and geodetic parameters. It possesses the capability to estimate that set of orbital elements, station positions, measurement biases, and a set of force model parameters such that the orbital tracking data from multiple arcs of multiple satellites best fit the entire set of estimated parameters. GEODYN consists of 113 different program segments, including the main program, subroutines, functions, and block data routines. All are in G or H level FORTRAN and are currently operational on GSFC's IBM 360/95 and IBM 360/91.

Prime Contract Awards by Service Category and Federal Supply Classification, Fiscal Years 1980, 1981, 1982, 1983.

DTIC Science & Technology

1983-01-01

GYMNASTIC EQUIPMENT 1,773 2 e94 3,938 2 49P TOTAL 4,552 5,038 8 292 5 278 79 CLEANING EQUIPMENT AND SUPPLIES 7910 FLOOR POLISHERS AND VACUUM CLEANERS 1,188...8020 PAINT AND ARTISTS BRUSHES 10 67 11 0 8030 PRESERVATIVE AND SEALING COMPOUNDS 851 8.340 2.169 1.183 8040 ADHESIVES 272 447 839 278 TOTAL 7.288 18,248

Extraneural findings during peripheral nerve ultrasound: Prevalence and further assessment.

PubMed

Bignotti, Bianca; Zaottini, Federico; Airaldi, Sonia; Martinoli, Carlo; Tagliafico, Alberto

2018-01-01

In this study we evaluated the frequency and further assessment of extraneural findings encountered during peripheral nerve ultrasound (US). Our retrospective review identified 278 peripheral nerve US examinations of 229 patients performed between December 2014 and December 2015. Reports were reviewed to assess the number of studies without peripheral nerve abnormalities and the frequency and further assessment of extraneural findings. A total of 107 peripheral nerve US examinations of 90 patients (49 men and 41 women, mean age 55 ± 16 years) did not report peripheral nerve abnormalities. Extraneural findings were observed in 24 of 107 (22.4%) studies. Fifteen of the 278 [5.4% (95% confidence interval 2.7%-8.1%)] studies led to a recommendation for additional imaging or clinical evaluation of an extraneural finding. At least 5.4% (15 of 278) of peripheral nerve US studies led to additional clinical or imaging assessment. Muscle Nerve 57: 65-69, 2018. © 2017 Wiley Periodicals, Inc.

9 CFR 113.113 - Autogenous biologics.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Autogenous biologics. 113.113 Section 113.113 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS...

Design selection of an innovative tool holder for ultrasonic vibration assisted turning (IN-UVAT) using finite element analysis simulation

NASA Astrophysics Data System (ADS)

Rachmat, Haris; Ibrahim, M. Rasidi; Hasan, Sulaiman bin

2017-04-01

On of high technology in machining is ultrasonic vibration assisted turning. The design of tool holder was a crucial step to make sure the tool holder is enough to handle all forces on turning process. Because of the direct experimental approach is expensive, the paper studied to predict feasibility of tool holder displacement and effective stress was used the computational in finite element simulation. SS201 and AISI 1045 materials were used with sharp and ramp corners flexure hinges on design. The result shows that AISI 1045 material and which has ramp corner flexure hinge was the best choice to be produced. The displacement is around 11.3 micron and effective stress is 1.71e+008 N/m2 and also the factor of safety is 3.10.

The origin of cellular life.

PubMed

Ingber, D E

2000-12-01

This essay presents a scenario of the origin of life that is based on analysis of biological architecture and mechanical design at the microstructural level. My thesis is that the same architectural and energetic constraints that shape cells today also guided the evolution of the first cells and that the molecular scaffolds that support solid-phase biochemistry in modern cells represent living microfossils of past life forms. This concept emerged from the discovery that cells mechanically stabilize themselves using tensegrity architecture and that these same building rules guide hierarchical self-assembly at all size scales (Sci. Amer 278:48-57;1998). When combined with other fundamental design principles (e.g., energy minimization, topological constraints, structural hierarchies, autocatalytic sets, solid-state biochemistry), tensegrity provides a physical basis to explain how atomic and molecular elements progressively self-assembled to create hierarchical structures with increasingly complex functions, including living cells that can self-reproduce.

The origin of cellular life

NASA Technical Reports Server (NTRS)

Ingber, D. E.

2000-01-01

This essay presents a scenario of the origin of life that is based on analysis of biological architecture and mechanical design at the microstructural level. My thesis is that the same architectural and energetic constraints that shape cells today also guided the evolution of the first cells and that the molecular scaffolds that support solid-phase biochemistry in modern cells represent living microfossils of past life forms. This concept emerged from the discovery that cells mechanically stabilize themselves using tensegrity architecture and that these same building rules guide hierarchical self-assembly at all size scales (Sci. Amer 278:48-57;1998). When combined with other fundamental design principles (e.g., energy minimization, topological constraints, structural hierarchies, autocatalytic sets, solid-state biochemistry), tensegrity provides a physical basis to explain how atomic and molecular elements progressively self-assembled to create hierarchical structures with increasingly complex functions, including living cells that can self-reproduce.

A RecA Protein Surface Required for Activation of DNA Polymerase V

PubMed Central

Gruber, Angela J.; Erdem, Aysen L.; Sabat, Grzegorz; Karata, Kiyonobu; Jaszczur, Malgorzata M.; Vo, Dan D.; Olsen, Tayla M.; Woodgate, Roger; Goodman, Myron F.; Cox, Michael M.

2015-01-01

DNA polymerase V (pol V) of Escherichia coli is a translesion DNA polymerase responsible for most of the mutagenesis observed during the SOS response. Pol V is activated by transfer of a RecA subunit from the 3'-proximal end of a RecA nucleoprotein filament to form a functional complex called DNA polymerase V Mutasome (pol V Mut). We identify a RecA surface, defined by residues 112-117, that either directly interacts with or is in very close proximity to amino acid residues on two distinct surfaces of the UmuC subunit of pol V. One of these surfaces is uniquely prominent in the active pol V Mut. Several conformational states are populated in the inactive and active complexes of RecA with pol V. The RecA D112R and RecA D112R N113R double mutant proteins exhibit successively reduced capacity for pol V activation. The double mutant RecA is specifically defective in the ATP binding step of the activation pathway. Unlike the classic non-mutable RecA S117F (recA1730), the RecA D112R N113R variant exhibits no defect in filament formation on DNA and promotes all other RecA activities efficiently. An important pol V activation surface of RecA protein is thus centered in a region encompassing amino acid residues 112, 113, and 117, a surface exposed at the 3'-proximal end of a RecA filament. The same RecA surface is not utilized in the RecA activation of the homologous and highly mutagenic RumA'2B polymerase encoded by the integrating-conjugative element (ICE) R391, indicating a lack of structural conservation between the two systems. The RecA D112R N113R protein represents a new separation of function mutant, proficient in all RecA functions except SOS mutagenesis. PMID:25811184

21 CFR 173.342 - Chlorofluorocarbon 113 and perfluorohexane.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Chlorofluorocarbon 113 and perfluorohexane. 173.342... HUMAN CONSUMPTION Specific Usage Additives § 173.342 Chlorofluorocarbon 113 and perfluorohexane. A..., also known as fluorocarbon 113, CFC 113 and FC 113) and 1 percent perfluorohexane (CAS Reg. No. 355-42...

13 CFR 113.310 - Recruitment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Recruitment. 113.310 Section 113... Discrimination on the Basis of Sex in Admission and Recruitment Prohibited § 113.310 Recruitment. (a) Nondiscriminatory recruitment. A recipient to which §§ 113.300 through 113.310 apply shall not discriminate on the...

Pseudomonas granadensis sp. nov., a new bacterial species isolated from the Tejeda, Almijara and Alhama Natural Park, Granada, Spain.

PubMed

Pascual, Javier; García-López, Marina; Bills, Gerald F; Genilloud, Olga

2015-02-01

During the course of screening bacterial isolates as sources of as-yet unknown bioactive compounds with pharmaceutical applications, a chemo-organotrophic, Gram-negative bacterium was isolated from a soil sample taken from the Tejeda, Almijara and Alhama Natural Park, Granada, Spain. Strain F-278,770(T) was oxidase- and catalase-positive, aerobic, with a respiratory type of metabolism with oxygen as the terminal electron acceptor, non-spore-forming and motile by one polar flagellum, although some cells had two polar flagella. Phylogenetic analysis of the 16S rRNA, gyrB, rpoB and rpoD genes revealed that strain F-278,770(T) belongs to the Pseudomonas koreensis subgroup (Pseudomonas fluorescens lineage), with Pseudomonas moraviensis, P. koreensis, P. baetica and P. helmanticensis as its closest relatives. Chemotaxonomic traits such as polar lipid and fatty acid compositions and G+C content of genomic DNA corroborated the placement of strain F-278,770(T) in the genus Pseudomonas. DNA-DNA hybridization assays and phenotypic traits confirmed that this strain represents a novel species of the genus Pseudomonas, for which the name Pseudomonas granadensis sp. nov. is proposed. The type strain is F-278,770(T) ( = DSM 28040(T) = LMG 27940(T)). © 2015 Fundacion MEDINA, Centro de Excelencia en Investigacion de Medicamentos Innovadores en Andalucia.

Development of a long-acting injectable formulation with nanoparticles of rilpivirine (TMC278) for HIV treatment.

PubMed

Baert, Lieven; van 't Klooster, Gerben; Dries, Willy; François, Marc; Wouters, Alfons; Basstanie, Esther; Iterbeke, Koen; Stappers, Fred; Stevens, Paul; Schueller, Laurent; Van Remoortere, Pieter; Kraus, Guenter; Wigerinck, Piet; Rosier, Jan

2009-08-01

Long-acting parenteral formulations of antiretrovirals could facilitate maintenance and prophylactic treatment in HIV. Using the poorly water- and oil-soluble non-nucleoside reverse transcriptase inhibitor (NNRTI) TMC278 (rilpivirine) as base or hydrochloride (HCl), nanosuspensions were prepared by wet milling (Elan NanoCrystal technology) in an aqueous carrier. Laser diffraction showed that the average particles size were (1) close to the targeted size proportionality (200-400-800 nm), with increasing distributions the larger the average particle size, and (2) were stable over 6 months. Following single-dose administration, the plasma concentration profiles showed sustained release of TMC278 over 3 months in dogs and 3 weeks in mice. On comparison of intramuscular and subcutaneous injection of 5mg/kg (200 nm) in dogs, the subcutaneous route resulted in the most stable plasma levels (constant at 25 ng/mL for 20 days, after which levels declined slowly to 1-3 ng/mL at 3 months); 200 nm nanosuspensions achieved higher and less variable plasma concentration profiles than 400 and 800 nm nanosuspensions. In mice, the pharmacokinetic profiles after a single 20mg/kg dose (200 nm) were similar with two different surfactants used (poloxamer 338, or d-alpha-tocopheryl polyethylene glycol 1000 succinate). In conclusion, this study provides proof-of-concept that 200-nm sized TMC278 nanosuspensions may act as long-acting injectable.

Conserved Noncoding Elements in the Most Distant Genera of Cephalochordates: The Goldilocks Principle

PubMed Central

Yue, Jia-Xing; Kozmikova, Iryna; Ono, Hiroki; Nossa, Carlos W.; Kozmik, Zbynek; Putnam, Nicholas H.; Yu, Jr-Kai; Holland, Linda Z.

2016-01-01

Cephalochordates, the sister group of vertebrates + tunicates, are evolving particularly slowly. Therefore, genome comparisons between two congeners of Branchiostoma revealed so many conserved noncoding elements (CNEs), that it was not clear how many are functional regulatory elements. To more effectively identify CNEs with potential regulatory functions, we compared noncoding sequences of genomes of the most phylogenetically distant cephalochordate genera, Asymmetron and Branchiostoma, which diverged approximately 120–160 million years ago. We found 113,070 noncoding elements conserved between the two species, amounting to 3.3% of the genome. The genomic distribution, target gene ontology, and enriched motifs of these CNEs all suggest that many of them are probably cis-regulatory elements. More than 90% of previously verified amphioxus regulatory elements were re-captured in this study. A search of the cephalochordate CNEs around 50 developmental genes in several vertebrate genomes revealed eight CNEs conserved between cephalochordates and vertebrates, indicating sequence conservation over >500 million years of divergence. The function of five CNEs was tested in reporter assays in zebrafish, and one was also tested in amphioxus. All five CNEs proved to be tissue-specific enhancers. Taken together, these findings indicate that even though Branchiostoma and Asymmetron are distantly related, as they are evolving slowly, comparisons between them are likely optimal for identifying most of their tissue-specific cis-regulatory elements laying the foundation for functional characterizations and a better understanding of the evolution of developmental regulation in cephalochordates. PMID:27412606

21 CFR 173.342 - Chlorofluorocarbon 113 and perfluorohexane.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 3 2013-04-01 2013-04-01 false Chlorofluorocarbon 113 and perfluorohexane. 173... perfluorohexane. A mixture of 99 percent chlorofluorocarbon 113 (1,1,2-trichloro-1,2,2-trifluoroethane) (CAS Reg. No. 76-13-1, also known as fluorocarbon 113, CFC 113 and FC 113) and 1 percent perfluorohexane (CAS...

21 CFR 173.342 - Chlorofluorocarbon 113 and perfluorohexane.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 3 2012-04-01 2012-04-01 false Chlorofluorocarbon 113 and perfluorohexane. 173... perfluorohexane. A mixture of 99 percent chlorofluorocarbon 113 (1,1,2-trichloro-1,2,2-trifluoroethane) (CAS Reg. No. 76-13-1, also known as fluorocarbon 113, CFC 113 and FC 113) and 1 percent perfluorohexane (CAS...

21 CFR 173.342 - Chlorofluorocarbon 113 and perfluorohexane.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 3 2011-04-01 2011-04-01 false Chlorofluorocarbon 113 and perfluorohexane. 173... perfluorohexane. A mixture of 99 percent chlorofluorocarbon 113 (1,1,2-trichloro-1,2,2-trifluoroethane) (CAS Reg. No. 76-13-1, also known as fluorocarbon 113, CFC 113 and FC 113) and 1 percent perfluorohexane (CAS...

The generator coordinate Dirac-Fock method for open-shell atomic systems

NASA Astrophysics Data System (ADS)

Malli, Gulzari L.; Ishikawa, Yasuyuki

1998-11-01

Recently we developed generator coordinate Dirac-Fock and Dirac-Fock-Breit methods for closed-shell systems assuming finite nucleus and have reported Dirac-Fock and Dirac-Fock-Breit energies for the atoms He through Nobelium (Z=102) [see Refs. Reference 10Reference 11Reference 12Reference 13]. In this paper, we generalize our earlier work on closed-shell systems and develop a generator coordinate Dirac-Fock method for open-shell systems. We present results for a number of representative open-shell heavy atoms (with nuclear charge Z>80) including the actinide and superheavy transactinide (with Z>103) atomic systems: Fr (Z=87), Ac (Z=89), and Lr (Z=103) to E113 (eka-thallium, Z=113). The high accuracy obtained in our open-shell Dirac-Fock calculations is similar to that of our closed-shell calculations, and we attribute it to the fact that the representation of the relativistic dynamics of an electron in a spherical ball finite nucleus near the origin in terms of our universal Gaussian basis set is as accurate as that provided by the numerical finite difference method. The DF SCF energies calculated by Desclaux [At. Data. Nucl. Data Tables 12, 311 (1973)] (apart from a typographic error for Fr pointed out here) are higher than those reported here for atoms of some of the superheavy transactinide elements by as much as 5 hartrees (136 eV). We believe that this is due to the use by Desclaux of much larger atomic masses than the currently accepted values for these elements.

9 CFR 113.8 - In vitro tests for serial release.

Code of Federal Regulations, 2013 CFR

2013-01-01

... REQUIREMENTS Applicability § 113.8 In vitro tests for serial release. (a) Master Seed which has been established as pure, safe, and immunogenic shall be used for preparing seed for production as specified in the...) Subjecting the master seed to the applicable requirements prescribed in §§ 113.64, 113.100, 113.200, and 113...

9 CFR 113.8 - In vitro tests for serial release.

Code of Federal Regulations, 2012 CFR

2012-01-01

... REQUIREMENTS Applicability § 113.8 In vitro tests for serial release. (a) Master Seed which has been established as pure, safe, and immunogenic shall be used for preparing seed for production as specified in the...) Subjecting the master seed to the applicable requirements prescribed in §§ 113.64, 113.100, 113.200, and 113...

9 CFR 113.8 - In vitro tests for serial release.

Code of Federal Regulations, 2014 CFR

2014-01-01

... REQUIREMENTS Applicability § 113.8 In vitro tests for serial release. (a) Master Seed which has been established as pure, safe, and immunogenic shall be used for preparing seed for production as specified in the...) Subjecting the master seed to the applicable requirements prescribed in §§ 113.64, 113.100, 113.200, and 113...

Investigation of nanoparticle agglomeration on the effective thermal conductivity of a composite material

NASA Astrophysics Data System (ADS)

Webb, Anthony J.

Phase Change Materials (PCMs), like paraffin wax, can be used for passive thermal management of portable electronics if their overall bulk thermal conductivity is increased through the addition of highly conducting nanoparticles. Finite Element Analysis (FEA) is used to investigate the influence of nanoparticle agglomeration on the overall conductive thermal transport in a nanoenhanced composite by dictating the thermal conductivity of individual elements according to their local inclusion volume fraction and characteristics inside a low conducting PCM matrix. The inclusion density distribution is dictated by an agglomeration factor, and the effective thermal conductivity of each element is calculated from the nanoparticle volume fraction using a method similar to the Representative Volume Element (RVE) methodology. FEA studies are performed for 2-D and 3-D models. In the 2-D model, the grain boundary is fixed at x = 0 for simplicity. For the 3-D model, the grain boundary geometry is randomly varied. A negligible 2-D effect on thermal transport in the 2-D model is seen, so a 1-D thermal resistance network is created for comparison, and the results agree within 4%.The influence of the agglomeration factor and contact Biot number on the overall bulk thermal conductivity is determined by applying Fourier's Law on the entire simulated composite. For the 2-D and 3-D models with a contact Biot number above 1, the overall bulk thermal conductivity decreases prior to the percolation threshold being met and then increases with increasing agglomeration. Finally, a MatlabRTM based image processing tool is created to estimate the agglomeration factor based on an experimental image of a nanoparticle distribution, with a calculated approximate agglomeration value of Beta*L = 5 which results in a bulk thermal conductivity of 0.278 W/(m-K).

Informativeness of patient initial reports of adverse drug reactions. Can it be improved by a pharmacovigilance centre?

PubMed

Kheloufi, F; Default, A; Rouby, F; Laugier-Castellan, D; Boyer, M; Rodrigues, B; Ponte-Astoul, J; Jean-Pastor, M J; Blin, O; Micallef, J

2017-08-01

Little is known about the informativeness of initial patient reports before they are reviewed by a pharmacovigilance centre (PVC). We aim to describe the patterns of patient adverse drug reaction (ADR) reporting in France and estimate the contribution of a review by a PVC assessor on the informativeness of these reports. A retrospective study was conducted on patient reports between July 2011 and July 2015. Informativeness of 16 key elements of information (including drug start and end date, duration of treatment, time to onset and duration of the ADR, outcome, medical history and concomitant medication) was assessed in initial reports before and after review by a pharmacovigilance assessor. Overall, 240 reports concerning 522 ADR and involving 278 drugs were reported over this 4-year period. Mean number of available key elements of information in initial reports was increased from 11/16 to 15/16 after review of reports by the PVC. Time to onset and duration of the ADR were respectively available in only 51 and 58% of the reports before review compared to 83 and 90% after review. Medical history and concomitant medication were missing in 75% of the initial reports compared to less than 30% of the reports after review. Contacting the reporter enabled an increase of informativeness of most elements of information for more than 90% of the reports. Patient reports often need to be completed on key elements of information that are required to assess reports. Both upstream education of patients and downstream intervention of a pharmacovigilance assessor to complete missing information could help to enhance the informativeness of such reports.

Comparison of serum trace element levels in patients with or without pre-eclampsia.

PubMed

Farzin, Leila; Sajadi, Fattaneh

2012-10-01

In developing countries, nutritional deficiency of essential trace elements is a common health problem, particularly among pregnant women because of increased requirements of various nutrients. Accordingly, this study was initiated to compare trace elements status in women with or without pre-eclampsia. In this study, serum trace elements including zinc (Zn), selenium (Se), copper (Cu), calcium (Ca) and magnesium (Mg) were determined by using atomic absorption spectrometry (AAS) in 60 patients and 60 healthy subjects. There was no significant difference in the values of Cu between two groups (P > 0.05). A significant difference in Zn, Se, Ca and Mg levels were observed between patients with pre-eclampsia and control group (P < 0.001, P<0.01, P<0.01 and P<0.001, respectively). Zn, Se, Ca and Mg levels were found to be 76.49 ± 17.62 μg/ dl, 8.82 ± 2.10 μg/ dl, 8.65 ± 2.14 mg/dl and 1.51 ± 0.34 mg/dl in Pre-eclamptic cases, and these values were found statistically lower compared to the controls (100.61 ± 20.12 μg/dl, 10.47 ± 2.78 μg/dl, 9.77 ± 3.02 mg/dl and 1.78 ± 0.27 mg/dl, respectively). While Cu levels were 118.28 ± 16.92 and 116.55 ± 15.23 μg/dl in the patients and the healthy subjects, respectively. In addition, no significant difference was found between two groups with respect to Hemoglobin Concentration (HbC) and Total White Blood Cell Count (TWBC) (P>0.05). Our findings indicate that the levels of Zn, Se, Ca and Mg are significantly altered in pregnant women with pre-eclampsia. This research shows that these deficiencies can not due to hemodilution.

Cocoa butter-like lipid production ability of non-oleaginous and oleaginous yeasts under nitrogen-limited culture conditions.

PubMed

Wei, Yongjun; Siewers, Verena; Nielsen, Jens

2017-05-01

Cocoa butter (CB) extracted from cocoa beans is the main raw material for chocolate production. However, growing chocolate demands and limited CB production has resulted in a shortage of CB supply. CB is mainly composed of three different kinds of triacylglycerols (TAGs), POP (C16:0-C18:1-C16:0), POS (C16:0-C18:1-C18:0), and SOS (C18:0-C18:1-C18:0). The storage lipids of yeasts, mainly TAGs, also contain relative high-level of C16 and C18 fatty acids and might be used as CB-like lipids (CBL). In this study, we cultivated six different yeasts, including one non-oleaginous yeast strain, Saccharomyces cerevisiae CEN.PK113-7D, and five oleaginous yeast strains, Trichosporon oleaginosus DSM11815, Rhodotorula graminis DSM 27356, Lipomyces starkeyi DSM 70296, Rhodosporidium toruloides DSM 70398, and Yarrowia lipolytica CBS 6124, in nitrogen-limited medium and compared their CBL production ability. Under the same growth conditions, we found that TAGs were the main lipids in all six yeasts and that T. oleaginosus can produce more TAGs than the other five yeasts. Less than 3% of the total TAGs were identified as potential SOS in the six yeasts. However, T. oleaginosus produced 27.8% potential POP and POS at levels of 378 mg TAGs/g dry cell weight, hinting that this yeast may have potential as a CBL production host after further metabolic engineering in future.

Aero-disaster in Port Harcourt, Nigeria: a case study.

PubMed

Seleye-Fubara, D; Etebu, E N; Amakiri, Cnt

2011-01-01

Aero-disaster in Nigeria is posing a serious problem to government, the public and relatives of victims, as many lives are lost in a single event. A case study based on an incident at an international airport in Nigeria on December 10, 2005. Detailed autopsy was performed on 97 fully identified bodies out of the 106 victims. Variables considered include ages, sex, pattern of injuries and death as well as problems associated with identification of bodies. A total of 97 (91.5%) out of the 106 deaths recorded were autopsied. Nine (8.5%) bodies were beyond identification, and hence autopsy could not be properly done on them. Fifty-nine (60.8%) were males and 38 (39.2%) were females, giving a ratio of 1.4:1. Sixty-one (62.9%) were children and adolescents below the age of 20 years. Severe burns 27 (27.8%), multiple injuries with burns 21 (21.6%), inhalation of fumes 20 (20.6%), multiple injuries only 16 (16.5%), severe head injury alone 11 (11.3%) and ruptured viscous 2 (2.1%) were the causes of death at autopsy in that order of frequency. Aero-disaster, though rare in Port Harcourt, is posing a serious problem in Nigeria in recent times. Various agencies should be established to adequately control mass disasters in Nigeria. Adequate maintenance of aircraft and strict observation and enforcement of aviation laws may drastically reduce the frequency of accidents and subsequent deaths.

[Preliminary evaluation on self-developed dentin porcelain color prediction system].

PubMed

Chen, L; Lu, C; Li, X L; Zhu, X M; Zhang, S; Tan, J G

2016-09-01

To apply the self-developed dentin porcelain color prediction system in the fabrication of porcelain-fused-to-metal-crown(PFMC), and to evaluate its accuracy in color-matching. Twenty upper central incisors were recruited according to preset criteria, and three PFMC were made for each tooth using three shade-matching techniques. Group A: PFMC were made according to the result of visual color selection; Group B: an spectrophotometer-based color-matching technique was used; Group C: PFMC were fabricated with dentin porcelain powder calculated by the prediction system according to the L(*), a(*), b(*) value measured by a spectrophotometer. Color differences(ΔE) (measured by spectrophotometer) of three groups of crowns were calculated in the cervical, middle, and incisal regions. The results were analyzed using one-way ANOVA. Mean color differences in body regions were: Group A: 3.53±1.80, Group B: 2.86±1.63, Group C: 3.77±1.40(P>0.05), and those in incisal regions were: Group A: 2.70 ± 1.13, Group B: 2.80 ± 0.90, Group C: 3.04 ± 1.03(P>0.05). In cervical region, Group C had greater color difference than Group B(2.78±1.14)(P<0.05). Group A(3.80±2.02) and Group B, Group A and Group C had similar color difference(P>0.05). PFMC fabricated using self-developed dentin porcelain color prediction system had similar color matching compared with conventional and instrument-based methods.

Fabrication and efficacy evaluation of chloroquine nanoparticles in CFA-induced arthritic rats using TNF-α ELISA.

PubMed

Bhalekar, Mangesh R; Upadhaya, Prashant G; Madgulkar, Ashwini R

2016-03-10

Rheumatoid arthritis (RA), a chronic systemic autoimmune disease, stimulates various immune cells especially macrophages, causing release of various proinflammatory cytokines such as TNF-α leading to persistent synovitis. Chloroquine, an anti-malarial drug inhibits the production of TNF-α, thus, halting the disease progression. The aim of the present study was fabrication, characterization and demonstration of kinetic and dynamic efficacy of chloroquine loaded solid lipid nanoparticles (CQ-SLNs) in arthritic rats and in lowering TNF-α levels. CQ-SLNs were prepared using melt homogenization method and subjected to lyophilization. The particle size, zeta potential, PDI and entrapment efficiency were found to be 113.6±0.15nm, -27.8±1.21mV, 0.125±0.03 and 93.45±0.43% respectively. Ex vivo endocytic uptake studies revealed engrossment of endocytic pathways in the uptake of SLN from intestine. Plasma drug profile upon pharmacokinetic evaluation demonstrated increased AUC, half-life and decreased elimination rate of the drug. Pharmacodynamic studies revealed reduction in the paw volume, bone erosion and cartilage destruction, the same was also reflected in histopathological studies. The TNF-α ELISA concluded that the TNF-α level was significantly reduced in the synovial fluid upon treatment with CQ-SLN, thus, leading to the conclusion that CQ-SLN could be used as a potential in reducing inflammatory TNF-α at the arthritic site and halting the disease progression. Copyright © 2016 Elsevier B.V. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yamashita, T.; Fujino, T.; Masaki, N.

The structural parameters of ..cap alpha..- and ..beta..-CdUO/sub 4/ crystals are determined by x-ray powder diffraction technique. ..cap alpha..-CdUO/sub 4/ is rhombohedral and cell parameters are a = 6.233(3) A and ..cap alpha.. = 36.12(5)/sup 0/. ..beta..-CdUO/sub 4/ crystallizes in a C-centered orthorhombic cell with a = 7.023(4), b = 6.849(3), c = 3.514(2) A. The space groups are R3m for ..cap alpha..-CdUO/sub 4/ and Cmmm for ..beta..-CdUO/sub 4/. ..cap alpha..-CdUO/sub 4/: 1U in (000), 1Cd in (1/2 1/2 1/2), 2O(1) in +-(uuu), 2O(2) in +-(vvv); u = 0.113, v= 0.350, Z = 1. ..beta..-CdUO/sub 4/: 2U in (000; 1/2more » 1/2 0), 2Cd in (1/2 0 1/2; 0 1/2 1/2), 40(1) in (0, +-y, 0; 1/2, 1/2 +-y, 0), 4O(2) in (+-x, 0, 1/2; 1/2 +-x, 1/2, 1/2); x = 0.159, y = 0.278, Z = 2. ..beta..-CdUO/sub 4/ contains collinear uranyl UO/sub 2//sup 2 +/ groups with a U-O(1) distance of 1.91 A, located either along or parallel to the c axis whereas the U-O(1) bond length in ..cap alpha..-CdUO/sub 4/ is 1.98 A which is longer than the usual uranyl bond length.« less

The crystal structures of α- and β-CdUO 4

NASA Astrophysics Data System (ADS)

Yamashita, Toshiyuki; Fujino, Takeo; Masaki, Norio; Tagawa, Hiroaki

1981-04-01

The structural parameters of α- and β-CdUO 4 crystals are determined by X-ray powder diffraction technique. α-CdUO 4 is rhombohedral and cell parameters are a = 6.233(3) Å and α = 36.12(5)°. β-CdUO 4 crystallizes in a C-centered orthorhombic cell with a = 7.023(4), b = 6.849(3), c = 3.514 (2) Å. The space groups are R overline3m for α-CdUO 4 and Cmmm for β-CdUO 4. α-CdUO 4: 1U in (000), 1Cd in ( {1}/{2}{1}/{2}{1}/{2}), 2O(1) in ±( uuu), 2O(2) in ±( vvv); u = 0.113, v = 0.350, Z = 1. β-CdUO 4: 2U in ( 000; {1}/{2}{1}/{2} 0 ), 2Cd in ( {1}/{2} 0 {1}/{2}; 0 {1}/{2}, {1}/{2}), 4O(1) in ( 0, ±y, 0; {1}/{2}, {1}/{2} ±y, 0 ), 4O(2) in ( ±x, 0, {1}/{2}; {1}/{2} ±x, {1}/{2}, {1}/{2}); x = 0.159, y = 0.278, Z = 2. β-CdUO 4 contains collinear uranyl UO 2+2 groups with a UO(1) distance of 1.91 Å, located either along or parallel to the c axis whereas the UO(1) bond length in α-CdUO 4 is 1.98 Å which is longer than the usual uranyl bond length.

Production and isolation of homologs of flerovium and element 115 at the Lawrence Livermore National Laboratory Center for Accelerator Mass Spectrometry

DOE PAGES

Despotopulos, John D.; Kmak, Kelly N.; Gharibyan, Narek; ...

2015-10-01

Here, new procedures have been developed to isolate no-carrier-added (NCA) radionuclides of the homologs and pseudo-homologs of flerovium (Hg, Sn) and element 115 (Sb), produced by 12–15 MeV proton irradiation of foil stacks with the tandem Van-de-Graaff accelerator at the Lawrence Livermore National Laboratory Center for Accelerator Mass Spectrometry (CAMS) facility. The separation of 113Sn from natIn foil was performed with anion-exchange chromatography from hydrochloric and nitric acid matrices. A cation-exchange chromatography method based on hydrochloric and mixed hydrochloric/hydroiodic acids was used to separate 124Sb from natSn foil. A procedure using Eichrom TEVA resin was developed to separate 197Hg frommore » Au foil. These results demonstrate the suitability of using the CAMS facility to produce NCA radioisotopes for studies of transactinide homologs.« less

Research of a Tram Headstock from Composite

NASA Astrophysics Data System (ADS)

Malkovsky, Zdenek; Kovandova, Hedvika

2014-08-01

The requirements for crashworthiness of railway vehicles are defined by the Railroad crashworthiness standard EN 15227. This standard is based on the findings of the characteristics of steel structures of front parts of railway vehicles. In the Czech Republic an extensive research was carried out within the project TIP FR-TI1/113 on application of composite sandwich structure elements in the design of the front cabins of a railway vehicle. The aim of the research work was to determine real possibilities of the composite sandwich structures for use in the construction of railway vehicles while considering the validity of the above-mentioned standard.

The effect of environmental initiatives on NASA specifications and standards activities

NASA Technical Reports Server (NTRS)

Griffin, Dennis; Webb, David; Cook, Beth

1995-01-01

The NASA Operational Environment Team (NOET) has conducted a survey of NASA centers specifications and standards that require the use of Ozone Depleting Substances (ODS's) (Chlorofluorocarbons (CFCs), Halons, and chlorinated solvents). The results of this survey are presented here, along with a pathfinder approach utilized at Marshall Space Flight Center (MSFC) to eliminate the use of ODS's in targeted specifications and standards. Presented here are the lessons learned from a pathfinder effort to replace CFC-113 in a significant MSFC specification for cleaning and cleanliness verification methods for oxygen, fuel and pneumatic service, including Shuttle propulsion elements.

Enhancement of piezoelectric constants induced by cation-substitution and two-dimensional strain effects on ZnO predicted by density functional perturbation theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nakamura, Kaoru, E-mail: n-kaoru@criepi.denken.or.jp; Higuchi, Sadao; Ohnuma, Toshiharu

2016-03-21

Using density functional perturbation theory, we investigated the effect of various substitutional dopant elements and in-plane strain on the piezoelectric properties of ZnO. The piezoelectric stress constant e{sub 33} of doped ZnO was found to depend on the formal charge of the substitutional dopant. By decomposing the piezoelectric stress constant e{sub 33} into the individual atomic contributions, the change in the piezoelectric properties was found to originate from a change in the coupling between the atomic displacement and the strain. Furthermore, we found that in-plane tensile strain along the a axis, which is specific to the thin film, can enhancemore » the piezoelectric constant of ZnO. A phase transition from wurtzite to h-BN-type structure was found to occur with increasing in-plane tensile. The piezoelectric strain constant d{sub 33} was predicted to reach ∼200 pC/N for 2.78 at. % V-substituted ZnO at 5.5% in-plane strain, just before the phase transition. These theoretical results suggest that the piezoelectric constant of ZnO can be enhanced by controlling the in-plane strain via selection of the substrate material and dopant element.« less

Oxygen surface exchange kinetics and stability of (La,Sr) 2 CoO 4±δ/La 1-xSr xMO 3-δ (M = Co and Fe) hetero-interfaces at intermediate temperatures

DOE PAGES

Lee, Dongkyu; Lee, Yueh-Lin; Hong, Wesley T.; ...

2014-11-13

Heterostructured oxide interfaces created by decorating Ruddlesden-Popper phases (A2BO4) or perovskites on perovskites have shown not only pronounced cation segregation at the interface and in the A2BO4 structure but also much enhanced kinetics for oxygen electrocatalysis at elevated temperatures. In this study, we report and compare the time-dependent surface exchange kinetics and stability of (La 0.5Sr 0.5) 2CoO 4 -decorated (LSC 214) La 0.6Sr 0.4Co 0.2Fe 0.8O 3-δ (LSCF 113) and La 0.8Sr 0.2CoO 3-δ (LSC 113) thin films. While LSC 214 decoration on LSC 113 greatly reduced the degradation in the surface exchange kinetics as a function of timemore » relative to LSC 113, LSCF 113 with LSC 214 coverage showed comparable surface exchange kinetics and stability to LSCF 113. This difference can be explained by greater surface stability of LSCF 113 than LSC 113 under testing conditions, and that LSC 214 decoration on LSC 113 reduced the decomposition of LSC 113 to form secondary phases that impedes oxygen exchange kinetics, and thus resulted in enhanced stability. This hypothesis is supported by the observations that annealing at 550 °C led to the formation of Sr-rich secondary particles on LSC 113 while no such particles were observed on LSCF 113. Density functional theory (DFT) computation provides further support, which revealed greater capacity of surface Sr segregation for LSCF 113 having SrO termination than LSC 113 having (La 0.25Sr 0.75)O termination for the experimental conditions, and lower energy gain to move Sr from LSCF 113 into LSC 214 relative to the LSC 214-LSC 113 system.« less

21 CFR 173.342 - Chlorofluorocarbon 113 and perfluorohexane.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 3 2014-04-01 2014-04-01 false Chlorofluorocarbon 113 and perfluorohexane. 173... Additives § 173.342 Chlorofluorocarbon 113 and perfluorohexane. A mixture of 99 percent chlorofluorocarbon... 113 and FC 113) and 1 percent perfluorohexane (CAS Reg. No. 355-42-0) may be safely used in accordance...

Metal characterization of white hawthorn organs and infusions.

PubMed

Juranović Cindrić, Iva; Zeiner, Michaela; Konanov, Darija Mihajlov; Stingeder, Gerhard

2015-02-18

Hawthorn is one of the most commonly used European and North American phytopharmaceuticals. Because there is no information on metals in seeds, and only rare data for leaves and flowers, the aim of the present study was elemental analysis of the white hawthorn (Crataegus monogyna) by inductively coupled plasma emission spectrometry (ICP-AES) or inductively coupled plasma mass spectrometry (ICP-MS) after digestion in a microwave-assisted system. The limits of detection are below 2 μg/g for ICP-AES and 0.5 μg/g for ICP-MS. Hawthorn leaves and flowers contain essential elements at concentrations (mean values, RSD 2-8%) in mg/g of Ca, 1-4; K, 4-5; Mg, 1-2; and Na, <0.2); and at μg/g levels of Ba, 1-10; Co, <0.16; Cr, <1.4; Cu, 0.6-7; Fe, 1-37; Li, <0.5; Mn, 1-13; Mo, <0.17; Ni, <0.6; Sr, 0.2-2; and Zn, 1-31. Toxic elements were found in low quantities: As (<0.04), Cd (0.04-0.1), and Pb (0.1-2). Up to 10% of the metals is extracted into the infusions. The analyzed plant parts and infusions contain essential elements justifying its use as a medicinal plant, whereas the low quantities of harmful elements will not pose any risk to humans when consumed.

21 CFR 113.5 - Current good manufacturing practice.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Current good manufacturing practice. 113.5 Section... CONTAINERS General Provisions § 113.5 Current good manufacturing practice. The criteria in §§ 113.10, 113.40..., methods, practices, and controls used by the commercial processor in the manufacture, processing, or...

Installation Restoration Program. Phase 2. Confirmation/Quantification. Stage 1. Air Force Plant 38, Porter, New York, RCRA (Resource Conservation and Recovery Act) Sites

DTIC Science & Technology

1988-04-01

sites throughout Alaska, Idaho , Oregon, and Washington, including work at 10 sites on the National Priorities List. Major geohydrologic investigations...Mary’s Hospital, 5300 Military Rd., Lewiston , 278-4000 Hospital Emergetcy Room Niagara Falls Memorial Medical Center, 621 10th N.F. 278-4000 Poison...Hospital ( Lewiston ): Exit AFP 38; head West on Balmer Road; Turn left and head south on State Highway 18; Turn left on State Highway 104 ( Lewiston Rd

Biological and Ecological Effects of Wastewater Discharges from Cruise Ships in Alaska

DTIC Science & Technology

2003-09-01

Tributyltin ( TBT ) 4.97 2.78 7.43 24.8 0.00 189 5.0 Total Butyltins 9.5 2.8 19.8 36.7 0.00 278 3.9 Silver (Ag) 0.7 0.15 1.70 1.01 0.03 6.48 1.4...bibliography, the reader is urged to consult the Panel report [2]. II. Background and Approach Stakeholders were especially concerned about: (1) the toxicity ...estimated and compared to concentrations known to result in toxicity and bioaccumulation. Contami- nants of concern to the Panel included

Origin discrimination of defatted pork via trace elements profiling, stable isotope ratios analysis, and multivariate statistical techniques.

PubMed

Park, Yu Min; Lee, Cheong Mi; Hong, Joon Ho; Jamila, Nargis; Khan, Naeem; Jung, Jong-Hyun; Jung, Young-Chul; Kim, Kyong Su

2018-09-01

This study verified the origin of 346 defatted Korean and non-Korean pork samples via trace elements profiling, and C and N stable isotope ratios analysis. The analyzed elements were 6 Li, 7 Li, 10 B, 11 B, 51 V , 50 Cr, 52 Cr, 53 Cr, 55 Mn, 58 Ni, 60 Ni, 59 Co, 63 Cu, 65 Cu, 64 Zn, 66 Zn, 69 Ga, 71 Ga, 75 As, 82 Se, 84 Sr, 86 Sr, 87 Sr, 88 Sr, 85 Rb, 94 Mo, 95 Mo, 97 Mo, 107 Ag, 109 Ag, 110 Cd, 111 Cd, 113 Cd, 112 Cd, 114 Cd, 116 Cd, 133 Cs, 206 Pb, 207 Pb, and 208 Pb. Content (mg/kg) of 51 V (0.012), 50 Cr (0.882), 75 As (0.017), 85 Rb (57.7), and 87 Sr (46.3) were high in Korean pork samples whereas 6 Li, 7 Li, 59 Co, 55 Mn, 58 Ni, 84 Sr, 86 Sr, 88 Sr, 111 Cd, and 133 Cs were found higher in non-Korean samples. The results of discriminant analysis showed that the trace elements content and stable isotope ratios were significant for the discrimination of geographical origins with a perfect discrimination rate of 100%. Copyright © 2018 Elsevier Ltd. All rights reserved.

26 CFR 1.113-1 - Mustering-out payments for members of the Armed Forces.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Forces. 1.113-1 Section 1.113-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY....113-1 Mustering-out payments for members of the Armed Forces. For the purposes of the exclusion from gross income under section 113 of mustering-out payments with respect to service in the Armed Forces...

Investigation of activation cross sections of deuteron induced reactions on indium up to 40 MeV for production of a 113 Sn/113m In generator.

PubMed

Tárkányi, F; Hermanne, A; Király, B; Takács, S; Ditrói, F; Baba, M; Ignatyuk, A V

2011-01-01

(113)Sn (115.09 d) is the parent nuclide of the (113)Sn/(113m)In generator system. (113m)In (99.476 min) is used in diagnostic nuclear medicine and as an Auger-electron emitter is a candidate for internal radiotherapy. Excitation functions of the (nat)In(d,x) (113 mg)Sn, (116 m)In, (ind115m)In, (114m)In, (ind113m)In, (cum111)In, (115g)Cd,(111m)Cd reactions were measured up to 40 MeV for the first time. The experimental results were compared with the curves calculated with the ALICE-D and EMPIRE-D theoretical model codes and curves given in the EAF-2007 and TENDL-2009 databases. Thick target yields, impurity levels and specific activities for the optimal energy range were deduced and compared with the same parameters of other charged particle production routes of (113)Sn. Copyright © 2010 Elsevier Ltd. All rights reserved.

STS-92 crew get training on driving the M-113 armored vehicle

NASA Technical Reports Server (NTRS)

2000-01-01

As part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities, members of the STS-92 crew get instructions about the M-113 they are seated in at Launch Pad 39A. Seen on the left are Pilot Pam Melroy and Mission Specialists Leroy Chaio and Koichi Wakata of Japan In the middle, giving the instructions, is Capt. George Hoggard, trainer with the KSC Fire Department. At right are Commander Brian Duffy (leaning back) and Mission Specialist Michael Lopez-Alegria. The other crew members (not seen) are Mission Specialists Jeff Wisoff and Bill McArthur. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

Hydrodynamic interactions in freely suspended liquid crystal films

NASA Astrophysics Data System (ADS)

Kuriabova, Tatiana; Powers, Thomas R.; Qi, Zhiyuan; Goldfain, Aaron; Park, Cheol Soo; Glaser, Matthew A.; Maclennan, Joseph E.; Clark, Noel A.

2016-11-01

Hydrodynamic interactions play an important role in biological processes in cellular membranes, a large separation of length scales often allowing such membranes to be treated as continuous, two-dimensional (2D) fluids. We study experimentally and theoretically the hydrodynamic interaction of pairs of inclusions in two-dimensional, fluid smectic liquid crystal films suspended in air. Such smectic membranes are ideal systems for performing controlled experiments as they are mechanically stable, of highly uniform structure, and have well-defined, variable thickness, enabling experimental investigation of the crossover from 2D to 3D hydrodynamics. Our theoretical model generalizes the Levine-MacKintosh theory of point-force response functions and uses a boundary-element approach to calculate the mobility matrix for inclusions of finite extent. We describe in detail the theoretical and computational approach previously outlined in Z. Qi et al., Phys. Rev. Lett. 113, 128304 (2014), 10.1103/PhysRevLett.113.128304 and extend the method to study the mutual mobilities of inclusions with asymmetric shapes. The model predicts well the observed mutual mobilities of pairs of circular inclusions in films and the self-mobility of a circular inclusion in the vicinity of a linear boundary.

13 CFR 113.535 - Effect of state or local law or other requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Effect of state or local law or other requirements. 113.535 Section 113.535 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION... obligation to comply with §§ 113.500 through 113.550 is not obviated or alleviated by the existence of any...

Carbapenemase-Producing Enterobacteriaceae in Yunnan Province, China.

PubMed

Rui, Zheng; Dehua, Liu; Hua, Niu; Yue, Feng; Yunmin, Xu; Jianhua, Li; Xueshan, Xia

2016-11-22

Among 144 carbapenem-resistant Enterobacteriaceae strains isolated from 4 hospitals in Yunnan province, 113 were identified as carbapenemase-producing Enterobacteriaceae (CPE). Bla KPC-2 (99/113, 87.6%) was the most common carbapenemase gene and Klebsiella pneumoniae (100/113, 88.5%) was the most common species. Bla NDM-1 (11/113, 9.7%), bla IMP-4 (10/113, 8.8%), and bla IMP-1 (1/113, 0.9%) genes were also detected. Extended-spectrum β-lactamase genes were common in CPE, and the SHV- and CTX-M-types were predominant.

7 CFR 1956.113-1956.117 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 14 2010-01-01 2009-01-01 true [Reserved] 1956.113-1956.117 Section 1956.113-1956.117...) PROGRAM REGULATIONS (CONTINUED) DEBT SETTLEMENT Debt Settlement-Community and Business Programs §§ 1956.113-1956.117 [Reserved] ...

48 CFR 32.113 - Customary contract financing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... financing. 32.113 Section 32.113 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Non-Commercial Item Purchase Financing 32.113 Customary contract financing. The solicitation must specify the customary contract financing offerors may...

Measurement of excitation functions and analysis of isomeric population in some reactions induced by proton on natural indium at low energy

NASA Astrophysics Data System (ADS)

Muhammed Shan, P. T.; Musthafa, M. M.; Najmunnisa, T.; Mohamed Aslam, P.; Rajesh, K. K.; Hajara, K.; Surendran, P.; Nair, J. P.; Shanbagh, Anil; Ghugre, S.

2018-06-01

The excitation functions for reaction residues populated via 115In(p , p) 115 mIn, 115In(p , pn) 114 mIn, 115In(p , p 2 n) 113 mIn, 113In(p , p) 113 mIn, 115In(p , nα) 111 mCd, 115In(p , 3 n) 113Sn and 113In(p , n) 113Sn channels were measured over the proton energy range of 8-22 MeV using stacked foil activation technique. Theoretical analysis of the data were performed within the framework of two statistical model codes EMPIRE-3.2 and TALYS-1.8. Isomeric cross section ratio for isomeric pairs m,g 115In, m,g 114In, m,g 113In, 113Sn m,g and m,g 111Cd were determined for the first time. The dependence of isomeric cross section ratio on various factors are analysed.

Effects of temperature, pH, and ionic strength on the Henry's law constant of triethylamine

NASA Astrophysics Data System (ADS)

Leng, Chun-Bo; Roberts, Jason E.; Zeng, Guang; Zhang, Yun-Hong; Liu, Yong

2015-05-01

The Henry's law constants (KH) of triethylamine (TEA) in pure water and in 1-octanol were measured for the temperatures pertinent to the lower troposphere (278-298 K) using a bubble column system coupled to a Fourier transform infrared spectrometer. The KH values of TEA in water and 1-octanol at 298 K are 5.75 ± 0.86 mol L-1 atm-1 and 115.62 ± 5.78 mol L-1 atm-1. The KH values display strong dependence on temperature, pH, and ionic strength. The characteristic times for TEA to establish an equilibrium between gas and droplet with a size of 5.6 µm are ~33 s (298 K, pH = 5.6); ~8.9 × 102 s (278 K, pH = 5.6); ~1.3 × 103 s (298 K, pH = 4.0); and 3.6 × 104 s (278 K, pH = 4.0). The evaluation of TEA partitioning between gas phase and condensed phase implies that TEA predominantly resides in rainwater, and TEA loss to organic aerosol is negligible.

East Europe Report: Economic and Industrial Affairs

DTIC Science & Technology

1985-04-04

Losses Due to Power Cuts (RUDE PRAVO, PRAVDA, 21 Feb 85) .............................. 43 GERMAN DEMOCRATIC REPUBLIC Analysis of Factors Contributing to...PREGLED, 5 Mar 85) ................................ .110 Briefs Problems at Trepca 112 Fire in Urosevac Combine 112 Fire in Prizren Textile Plant 113...Possible Bankruptcies in Kosovo 113 Private Farm Planting 113 Trade With Iraq 113 Rail Agreement With Hungary, USSR 113 Kosovo Water System Delay 114 -b

40 CFR 405.113 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 28 2010-07-01 2010-07-01 true [Reserved] 405.113 Section 405.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS DAIRY PRODUCTS PROCESSING POINT SOURCE CATEGORY Condensed Whey Subcategory § 405.113 [Reserved] ...

40 CFR 51.113 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 2 2010-07-01 2010-07-01 false [Reserved] 51.113 Section 51.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS REQUIREMENTS FOR PREPARATION, ADOPTION, AND SUBMITTAL OF IMPLEMENTATION PLANS Control Strategy § 51.113 [Reserved] ...

48 CFR 432.113 - Customary contract financing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... financing. 432.113 Section 432.113 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Non-Commercial Item Purchase Financing 432.113 Customary contract financing. The contracting officer may determine the necessity for customary contract financing. The...

49 CFR 380.113 - Employer responsibilities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 5 2010-10-01 2010-10-01 false Employer responsibilities. 380.113 Section 380.113 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY....113 Employer responsibilities. (a) No motor carrier shall: (1) Allow, require, permit or authorize an...

7 CFR 1220.113 - Marketing.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false Marketing. 1220.113 Section 1220.113 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION Soybean Promotion and Research Order Definitions § 1220.113 Marketing. The term...

7 CFR 1220.113 - Marketing.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 10 2013-01-01 2013-01-01 false Marketing. 1220.113 Section 1220.113 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION Soybean Promotion and Research Order Definitions § 1220.113 Marketing. The term...

7 CFR 1220.113 - Marketing.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false Marketing. 1220.113 Section 1220.113 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION Soybean Promotion and Research Order Definitions § 1220.113 Marketing. The term...

7 CFR 1220.113 - Marketing.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Marketing. 1220.113 Section 1220.113 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION Soybean Promotion and Research Order Definitions § 1220.113 Marketing. The term...

42 CFR 66.113 - Publications.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Publications. 66.113 Section 66.113 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL RESEARCH SERVICE AWARDS Direct Awards § 66.113 Publications. Publication, distribution, and...

42 CFR 66.113 - Publications.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Publications. 66.113 Section 66.113 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL RESEARCH SERVICE AWARDS Direct Awards § 66.113 Publications. Publication, distribution, and...

42 CFR 66.113 - Publications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Publications. 66.113 Section 66.113 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL RESEARCH SERVICE AWARDS Direct Awards § 66.113 Publications. Publication, distribution, and...

42 CFR 66.113 - Publications.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Publications. 66.113 Section 66.113 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL RESEARCH SERVICE AWARDS Direct Awards § 66.113 Publications. Publication, distribution, and...

42 CFR 66.113 - Publications.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Publications. 66.113 Section 66.113 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL RESEARCH SERVICE AWARDS Direct Awards § 66.113 Publications. Publication, distribution, and...

32 CFR 724.113 - Application.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Application. 724.113 Section 724.113 National... Definitions § 724.113 Application. In the context of this Manual, a written application to the NDRB for the... must be used for the application. ...

Electronic structure and properties of MAu and MOH, where M = Tl and Nh: New data

NASA Astrophysics Data System (ADS)

Pershina, V.; Iliaš, M.

2018-02-01

Properties of the MAu and MOH (M = Tl and element 113, Nh) molecules were calculated using the 2c-DFT method. The obtained data are needed for evaluation of reactivity of Nh studied by gas-phase chromatography experiments. Results show that Nh should be less reactive (or more volatile) than Tl, both with respect to gold and the hydroxyl group. The reason for that are strong relativistic effects on the valence 7s and 7p electron shells. In difference to the atoms, NhOH may be less volatile than TlOH due to its larger both dipole moment and anisotropic polarizability.

First Responder Immersive Training Simulation Environment (FRITSE): Downwind Hazard Modeling of Scenarios

DTIC Science & Technology

2014-07-31

evaporating from the ground surface at a constant rate of 2.78 kg/s over 13 a period of 30 minutes, at which time all chlorine in the liquid pool would...caused 10,000 kg of chlorine to be expelled into the atmosphere in the form of vapor/aerosol droplets over a short time of 100 sec, at a release rate of...1,800 sec) at a constant rate of 5,000/1,800 =2.78 kg/s, at which time all chlorine in the liquid pool would have evaporated, and treated as “continuous

Thermal Aspects of Future Spacecraft Thermal Management Systems.

DTIC Science & Technology

1986-07-01

eutectic salt ) (278 278) (168) (n-a n-a) (0.78 0.78) (2290 2290) (inexpensive))) (95.4 % NaNO3 - 4.6 % NaCl) (inorganic eutectic salt ) (297 297) (178) (n-a...n-a) (0.69 0.69) (2260 2260) (inexpensive))) (69.9 % CaC12 - 30.1 % NaCI) (inorganic eutectic salt ) (490 490) (233) (n-a n-a) (4 4) (2400 2400...inexpensive))) (46.2 % KC1 - 29.9 X CaCI2 -23.9 X NaCi) (inorganic eutectic salt ) (515 515) (265) (n-a n-a) (3.8 3.8) (2160 2160) (inexpensive))) (79

PEGylation of zinc nanoparticles amplifies their ability to enhance olfactory responses to odorant

PubMed Central

Singletary, Melissa; Hagerty, Samantha; Muramoto, Shin; Daniels, Yasmine; MacCrehan, William A.; Stan, Gheorghe; Lau, June W.; Pustovyy, Oleg; Globa, Ludmila; Morrison, Edward E.; Sorokulova, Iryna

2017-01-01

Olfactory responses are intensely enhanced with the addition of endogenous and engineered primarily-elemental small zinc nanoparticles (NPs). With aging, oxidation of these Zn nanoparticles eliminated the observed enhancement. The design of a polyethylene glycol coating to meet storage requirements of engineered zinc nanoparticles is evaluated to achieve maximal olfactory benefit. The zinc nanoparticles were covered with 1000 g/mol or 400 g/mol molecular weight polyethylene glycol (PEG). Non-PEGylated and PEGylated zinc nanoparticles were tested by electroolfactogram with isolated rat olfactory epithelium and odorant responses evoked by the mixture of eugenol, ethyl butyrate and (±) carvone after storage at 278 K (5 oC), 303 K (30 oC) and 323 K (50 oC). The particles were analyzed by atomic force microscopy, transmission electron microscopy, X-ray photoelectron spectroscopy, and laser Doppler velocimetry. Our data indicate that stored ZnPEG400 nanoparticles maintain physiologically-consistent olfactory enhancement for over 300 days. These engineered Nanoparticles support future applications in olfactory research, sensitive detection, and medicine. PMID:29261701

Synthesis, crystal, and biological activity of a novel carbene silver(I) complex with imidazole derivative

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jiu-Fu, Lu, E-mail: jiufulu@163.com; Hong-Guang, Ge; Juan, Shi

2015-12-15

Reaction of 2-(1-methyl-1,2-dihydroimidazol-3-yl)acetonitrile tetrafluoroborate with silver oxide in dichloromethane readily yields [Ag(DIM){sub 2}]BF{sub 4}, where DIM is 2-(1-methyl-1, 2-dihydroimidazol-3-yl)acetonitrile, representing a carbene organic ligand. The title compound was characterized by elemental analysis, IR, MS and single crystal X-ray diffraction. The crystal is of monoclinic system, space group C2/c with a = 14.010(18), b = 8.303(11), c = 14.936(20) Å, β = 93.910(4)°, V = 1639(4) Å{sup 3}, Z = 4, D{sub x} = 1.771 g/cm{sup 3}, F (000) = 864, µ(MoK{sub α}) = 1.278 mm{sup –1}. The final R{sup 1} = 0.0711 and wR{sup 2} = 0.1903 for reflections withmore » I > 2σ(I). In addition, the preliminary biological test showed that the title compound had anti-fungus yeast activity.« less

Evaluation of an effective multifaceted implementation strategy for elective single-embryo transfer after in vitro fertilization.

PubMed

Kreuwel, I A M; van Peperstraten, A M; Hulscher, M E J L; Kremer, J A M; Grol, R P T M; Nelen, W L D M; Hermens, R P M G

2013-02-01

What is the relationship between the rate of elective single-embryo transfer (eSET) and couples' exposure to different elements of a multifaceted implementation strategy? Additional elements in a multifaceted implementation strategy do not result in an increased eSET rate. A multifaceted eSET implementation strategy with four different elements is effective in increasing the eSET rate by 11%. It is unclear whether every strategy element contributes equally to the strategy's effectiveness. An observational study was performed among 222 subfertile couples included in a previously performed randomized controlled trial. Of the 222 subfertile couples included, 109 couples received the implementation strategy and 113 couples received standard IVF care. A multivariate regression analysis assessed the effectiveness of four different strategy elements on the decision about the number embryos to be transferred. Questionnaires evaluated the experiences of couples with the different elements. Of the couples who received the implementation strategy, almost 50% (52/109) were exposed to all the four elements of the strategy. The remaining 57 couples who received two or three elements of the strategy could be divided into two further classes of exposure. Our analysis demonstrated that additional elements do not result in an increased eSET rate. In addition to the physician's advice, couples rated a decision aid and a counselling session as more important for their decision to transfer one or two embryos, compared with a phone call and a reimbursement offer (P < 0.001). The differences in eSET rate between exposure groups failed to reach significance, probably because of the small numbers of couples in each exposure group. Adding more elements to an implementation strategy does not always result in an increased effectiveness, which is in concordance with recent literature. This in-depth evaluation of a multifaceted intervention strategy could therefore help to modify strategies, by making them more effective and less expensive.

40 CFR 98.113 - Calculating GHG emissions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Calculating GHG emissions. 98.113 Section 98.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Ferroalloy Production § 98.113 Calculating GHG emissions. You...

40 CFR 89.113 - Smoke emission standard.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Smoke emission standard. 89.113 Section 89.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... and Certification Provisions § 89.113 Smoke emission standard. (a) Exhaust opacity from compression...

40 CFR 89.113 - Smoke emission standard.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Smoke emission standard. 89.113 Section 89.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... and Certification Provisions § 89.113 Smoke emission standard. (a) Exhaust opacity from compression...

40 CFR 89.113 - Smoke emission standard.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Smoke emission standard. 89.113 Section 89.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... and Certification Provisions § 89.113 Smoke emission standard. (a) Exhaust opacity from compression...

40 CFR 89.113 - Smoke emission standard.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Smoke emission standard. 89.113 Section 89.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... and Certification Provisions § 89.113 Smoke emission standard. (a) Exhaust opacity from compression...

13 CFR 113.510 - Recruitment.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Recruitment. 113.510 Section 113.510 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NONDISCRIMINATION IN FINANCIAL... Discrimination on the Basis of Sex in Employment in Education Programs Or Activities Prohibited § 113.510...

48 CFR 49.113 - Cost principles.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Cost principles. 49.113 Section 49.113 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS General Principles 49.113 Cost principles. The cost principles and procedures in the...

5 CFR 831.113 - Payments to children.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Payments to children. 831.113 Section 831.113 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) RETIREMENT Administration and General Provisions § 831.113 Payments to children. For purposes of...

5 CFR 831.113 - Payments to children.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Payments to children. 831.113 Section 831.113 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) RETIREMENT Administration and General Provisions § 831.113 Payments to children. For purposes of...

5 CFR 831.113 - Payments to children.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Payments to children. 831.113 Section 831.113 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) RETIREMENT Administration and General Provisions § 831.113 Payments to children. For purposes of...

5 CFR 831.113 - Payments to children.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Payments to children. 831.113 Section 831.113 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) RETIREMENT Administration and General Provisions § 831.113 Payments to children. For purposes of...

5 CFR 831.113 - Payments to children.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Payments to children. 831.113 Section 831.113 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) RETIREMENT Administration and General Provisions § 831.113 Payments to children. For purposes of...

40 CFR 113.2 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Applicability. 113.2 Section 113.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.2 Applicability. This subpart applies to...

40 CFR 113.1 - Purpose.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Purpose. 113.1 Section 113.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.1 Purpose. This subpart establishes size...

40 CFR 113.3 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Definitions. 113.3 Section 113.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.3 Definitions. As used in this subpart...

40 CFR 113.1 - Purpose.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Purpose. 113.1 Section 113.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.1 Purpose. This subpart establishes size...

40 CFR 113.5 - Exclusions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Exclusions. 113.5 Section 113.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.5 Exclusions. This subpart does not apply...

40 CFR 113.3 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Definitions. 113.3 Section 113.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.3 Definitions. As used in this subpart...

40 CFR 113.5 - Exclusions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Exclusions. 113.5 Section 113.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.5 Exclusions. This subpart does not apply...

40 CFR 113.2 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Applicability. 113.2 Section 113.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.2 Applicability. This subpart applies to...

18 CFR 388.113 - Accessing critical energy infrastructure information.

Code of Federal Regulations, 2014 CFR

2014-04-01

... energy infrastructure information. 388.113 Section 388.113 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES INFORMATION AND REQUESTS § 388.113 Accessing critical energy infrastructure information. (a) Scope. This section governs access to...

18 CFR 388.113 - Accessing critical energy infrastructure information.

Code of Federal Regulations, 2010 CFR

2010-04-01

... energy infrastructure information. 388.113 Section 388.113 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES INFORMATION AND REQUESTS § 388.113 Accessing critical energy infrastructure information. (a) Scope. This section governs access to...

18 CFR 388.113 - Accessing critical energy infrastructure information.

Code of Federal Regulations, 2012 CFR

2012-04-01

... energy infrastructure information. 388.113 Section 388.113 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES INFORMATION AND REQUESTS § 388.113 Accessing critical energy infrastructure information. (a) Scope. This section governs access to...

18 CFR 388.113 - Accessing critical energy infrastructure information.

Code of Federal Regulations, 2013 CFR

2013-04-01

... energy infrastructure information. 388.113 Section 388.113 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES INFORMATION AND REQUESTS § 388.113 Accessing critical energy infrastructure information. (a) Scope. This section governs access to...

18 CFR 388.113 - Accessing critical energy infrastructure information.

Code of Federal Regulations, 2011 CFR

2011-04-01

... energy infrastructure information. 388.113 Section 388.113 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES INFORMATION AND REQUESTS § 388.113 Accessing critical energy infrastructure information. (a) Scope. This section governs access to...

14 CFR 1240.113 - Financial accounting.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Financial accounting. 1240.113 Section 1240.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INVENTIONS AND CONTRIBUTIONS Awards for Scientific and Technical Contributions § 1240.113 Financial accounting. (a) An Award Check...

THG113.31, a specific PGF2alpha receptor antagonist, induces human myometrial relaxation and BKCa channel activation

PubMed Central

Doheny, Helen C; O'Reilly, Michael J; Sexton, Donal J; Morrison, John J

2007-01-01

Background PGF2alpha exerts a significant contractile effect on myometrium and is central to human labour. THG113.31, a specific non-competitive PGF2alpha receptor (FP) antagonist, exerts an inhibitory effect on myometrial contractility. The BKCa channel is ubiquitously encountered in human uterine tissue and plays a significant role in modulating myometrial cell membrane potential and excitability. The objective of this study was to investigate potential BKCa channel involvement in the response of human myometrium to THG113.31. Methods Single and whole-cell electrophysiological BKCa channel recordings from freshly dispersed myocytes, were investigated in the presence and absence of THG113.31. Functional studies investigated the effects of THG113.31 on isolated spontaneous myometrial contractions, in the presence and absence of the BKCa channel blocker, iberiotoxin. Results Single channel recordings identified the BKCa channel as a target of THG113.31. THG113.31 significantly increased the open state probability of these channels [control 0.023+/-0.006; 10 microM THG113.31 0.087+/-0.012 (P = 0.009); and 50 microM THG113.31 0.1356+/-0.018 (P = 0.001)]. In addition, THG113.31 increased whole-cell BKCa currents over a range of membrane potentials, and this effect was reversed by 100 nanoM IbTX. Isometric tension studies demonstrated that THG113.31 exerted a significant concentration-dependent relaxant effect on human myometrial tissue and pre-incubation of strips with IbTX abolished this effect on spontaneously occurring contractions. Conclusion These data suggests that activation of the BKCa channel may contribute, at least partially, to the uterorelaxant effect of THG113.31. PMID:17367527

14 CFR 1245.113 - Hearing procedure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Hearing procedure. 1245.113 Section 1245.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PATENTS AND OTHER INTELLECTUAL PROPERTY RIGHTS Patent Waiver Regulations § 1245.113 Hearing procedure. (a) If the petitioner requests an...

28 CFR 551.113 - Counseling.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Counseling. 551.113 Section 551.113... Pretrial Inmates § 551.113 Counseling. (a) When consistent with institution security and good order, pretrial inmates may be allowed the opportunity to receive counseling services with convicted inmates. (b...

28 CFR 551.113 - Counseling.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Counseling. 551.113 Section 551.113... Pretrial Inmates § 551.113 Counseling. (a) When consistent with institution security and good order, pretrial inmates may be allowed the opportunity to receive counseling services with convicted inmates. (b...

28 CFR 551.113 - Counseling.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Counseling. 551.113 Section 551.113... Pretrial Inmates § 551.113 Counseling. (a) When consistent with institution security and good order, pretrial inmates may be allowed the opportunity to receive counseling services with convicted inmates. (b...

28 CFR 551.113 - Counseling.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Counseling. 551.113 Section 551.113... Pretrial Inmates § 551.113 Counseling. (a) When consistent with institution security and good order, pretrial inmates may be allowed the opportunity to receive counseling services with convicted inmates. (b...

28 CFR 551.113 - Counseling.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Counseling. 551.113 Section 551.113... Pretrial Inmates § 551.113 Counseling. (a) When consistent with institution security and good order, pretrial inmates may be allowed the opportunity to receive counseling services with convicted inmates. (b...

13 CFR 113.130 - Effect of employment opportunities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Effect of employment opportunities. 113.130 Section 113.130 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NONDISCRIMINATION... Financial Assistance Introduction § 113.130 Effect of employment opportunities. The obligation to comply...

40 CFR 89.113 - Smoke emission standard.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Smoke emission standard. 89.113 Section 89.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED... Certification Provisions § 89.113 Smoke emission standard. (a) Exhaust opacity from compression-ignition nonroad...

46 CFR 113.05-7 - Environmental tests.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Environmental tests. 113.05-7 Section 113.05-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT General Provisions § 113.05-7 Environmental tests. Communication, alarm system...

24 CFR 886.113 - Physical condition standard; physical inspection requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Physical condition standard; physical inspection requirements. 886.113 Section 886.113 Housing and Urban Development Regulations... § 886.113 Physical condition standard; physical inspection requirements. (a) General. Housing used in...

24 CFR 886.113 - Physical condition standard; physical inspection requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Physical condition standard; physical inspection requirements. 886.113 Section 886.113 Housing and Urban Development REGULATIONS... § 886.113 Physical condition standard; physical inspection requirements. (a) General. Housing used in...

24 CFR 886.113 - Physical condition standard; physical inspection requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Physical condition standard; physical inspection requirements. 886.113 Section 886.113 Housing and Urban Development REGULATIONS... § 886.113 Physical condition standard; physical inspection requirements. (a) General. Housing used in...

24 CFR 886.113 - Physical condition standard; physical inspection requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Physical condition standard; physical inspection requirements. 886.113 Section 886.113 Housing and Urban Development REGULATIONS... § 886.113 Physical condition standard; physical inspection requirements. (a) General. Housing used in...

24 CFR 886.113 - Physical condition standard; physical inspection requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Physical condition standard; physical inspection requirements. 886.113 Section 886.113 Housing and Urban Development REGULATIONS... § 886.113 Physical condition standard; physical inspection requirements. (a) General. Housing used in...

47 CFR 5.113 - Adherence to program of research.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Adherence to program of research. 5.113 Section 5.113 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL EXPERIMENTAL RADIO SERVICE (OTHER THAN BROADCAST) Technical Standards and Operating Requirements § 5.113 Adherence to program of research...

46 CFR 113.30-1 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Applicability. 113.30-1 Section 113.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Internal Communications § 113.30-1 Applicability. This subpart applies to each self...

46 CFR 113.40-1 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Applicability. 113.40-1 Section 113.40-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Rudder Angle Indicator Systems § 113.40-1 Applicability. This subpart applies to...

46 CFR 113.30-1 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Applicability. 113.30-1 Section 113.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Internal Communications § 113.30-1 Applicability. This subpart applies to each self...

46 CFR 113.30-1 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Applicability. 113.30-1 Section 113.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Internal Communications § 113.30-1 Applicability. This subpart applies to each self...

46 CFR 113.30-1 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Applicability. 113.30-1 Section 113.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Internal Communications § 113.30-1 Applicability. This subpart applies to each self...

46 CFR 113.40-1 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Applicability. 113.40-1 Section 113.40-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Rudder Angle Indicator Systems § 113.40-1 Applicability. This subpart applies to...

46 CFR 113.30-1 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Applicability. 113.30-1 Section 113.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Internal Communications § 113.30-1 Applicability. This subpart applies to each self...

46 CFR 113.40-1 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Applicability. 113.40-1 Section 113.40-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Rudder Angle Indicator Systems § 113.40-1 Applicability. This subpart applies to...

23 CFR 470.113 - National Highway System procedures.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false National Highway System procedures. 470.113 Section 470.113 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH HIGHWAY SYSTEMS Federal-aid Highway Systems § 470.113 National Highway System procedures. (a) Proposals...

23 CFR 470.113 - National Highway System procedures.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false National Highway System procedures. 470.113 Section 470.113 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH HIGHWAY SYSTEMS Federal-aid Highway Systems § 470.113 National Highway System procedures. (a) Proposals...

23 CFR 470.113 - National Highway System procedures.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 23 Highways 1 2012-04-01 2012-04-01 false National Highway System procedures. 470.113 Section 470.113 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH HIGHWAY SYSTEMS Federal-aid Highway Systems § 470.113 National Highway System procedures. (a) Proposals...

23 CFR 470.113 - National Highway System procedures.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false National Highway System procedures. 470.113 Section 470.113 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH HIGHWAY SYSTEMS Federal-aid Highway Systems § 470.113 National Highway System procedures. (a) Proposals...

23 CFR 470.113 - National Highway System procedures.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false National Highway System procedures. 470.113 Section 470.113 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH HIGHWAY SYSTEMS Federal-aid Highway Systems § 470.113 National Highway System procedures. (a) Proposals...

42 CFR 53.113 - Community service.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Community service. 53.113 Section 53.113 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS, LOANS AND LOAN... To Pay; Community Service; Nondiscrimination. § 53.113 Community service. (a) Applicability. The...

46 CFR 113.40-1 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Applicability. 113.40-1 Section 113.40-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Rudder Angle Indicator Systems § 113.40-1 Applicability. This subpart applies to...

46 CFR 113.40-1 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Applicability. 113.40-1 Section 113.40-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Rudder Angle Indicator Systems § 113.40-1 Applicability. This subpart applies to...

Lunar bulk chemical composition: a post-Gravity Recovery and Interior Laboratory reassessment

PubMed Central

Taylor, G. Jeffrey; Wieczorek, Mark A.

2014-01-01

New estimates of the thickness of the lunar highlands crust based on data from the Gravity Recovery and Interior Laboratory mission, allow us to reassess the abundances of refractory elements in the Moon. Previous estimates of the Moon fall into two distinct groups: earthlike and a 50% enrichment in the Moon compared with the Earth. Revised crustal thicknesses and compositional information from remote sensing and lunar samples indicate that the crust contributes 1.13–1.85 wt% Al2O3 to the bulk Moon abundance. Mare basalt Al2O3 concentrations (8–10 wt%) and Al2O3 partitioning behaviour between melt and pyroxene during partial melting indicate mantle Al2O3 concentration in the range 1.3–3.1 wt%, depending on the relative amounts of pyroxene and olivine. Using crustal and mantle mass fractions, we show that that the Moon and the Earth most likely have the same (within 20%) concentrations of refractory elements. This allows us to use correlations between pairs of refractory and volatile elements to confirm that lunar abundances of moderately volatile elements such as K, Rb and Cs are depleted by 75% in the Moon compared with the Earth and that highly volatile elements, such as Tl and Cd, are depleted by 99%. The earthlike refractory abundances and depleted volatile abundances are strong constraints on lunar formation processes. PMID:25114309

Liver transplantation for Wilson's disease in pediatric patients: decision making and timing.

PubMed

Narumi, S; Umehara, M; Toyoki, Y; Ishido, K; Kudo, D; Kimura, N; Kobayashi, T; Sugai, M; Hakamada, K

2012-03-01

Transplantation for Wilson's disease occupies 1/3 of the cases for metabolic diseases in Japan. At the end of 2009, 109 transplantations had been performed including three deceased donor cases in the Japanese registry. We herein discuss problems of transplantation for Wilson's disease as well as its indication, timing, and social care. We retrospectively reviewed four fulminant cases and two chronic cases who underwent living donor liver transplantation. There were two boys and two girls. Four adolescents of average age 11.3 years underwent living donor liver transplantation. Duration from onset to transplantation ranged from 10 to 23 days. Average Model for End-stage Liver Disease (MELD) score was 27.8 (range=24-31). All patients were administrated chelates prior to transplantation. MELD, New Wilson's index, Japanese scoring for liver transplantation, and liver atrophy were useful tools for transplantation decision making; however, none of them was an independent decisive tool. Clinical courses after transplantation were almost uneventful. One girl, however, developed an acute rejection episode due to noncompliance at 3 years after transplantation. All patients currently survive without a graft loss. No disease recurrence had been noted even using living related donors. Two adults evaluated for liver transplantation were listed for deceased donor liver transplantation. Both candidates developed cirrhosis despite long-term medical treatment. There were no appropriate living donors for them. There are many problems in transplantation for Wilson's disease. The indications for liver transplantation should be considered individually using some decision-making tools. The safety of the living donor should be paid the most attention. Copyright © 2012 Elsevier Inc. All rights reserved.

Bullying and Its Associated Factors among School-Aged Adolescents in Thailand

PubMed Central

Pengpid, Supa

2013-01-01

The aim of this study were to assess bullying and its associated factors in school-going adolescents in Thailand. Using data from the Thailand Global School-Based Student Health Survey (GSHS) 2008, the prevalence of being bullied and its associated factors among adolescents (N = 2758) was assessed. The study found an overall prevalence of being bullied on one or more days during the past 30 days of 27.8%, 32.9% among males and 23.2% among females. The predominant forms of being bullied were among boys being hit, kicked, pushed, shoved around, or locked indoors and among girls making fun of with sexual jokes, comments, and gestures. Among boys risk factors for having been bullied were younger age (adjusted odds ratio to (AOR): 0.34; 95% confidence interval (CI): 0.18–0.65), having been in a physical fight (AOR: 3.64; 95% CI: 2.84–4.66), being physically inactive (AOR: 1.49; 95% CI: 1.04–2.15), truancy (AOR: 1.66; 95% CI: 1.13–2.45), and psychosocial distress (AOR: 2.07; 95% CI: 1.14–3.74), and among girls risk factors for having been bullied were having been in a physical fight (AOR: 2.91; 95% CI: 2.00–4.24), lack of parental bonding (AOR: 0.71; 95% CI: 0.51–0.99), and psychosocial distress (AOR: 2.37; 95% CI: 1.39–4.03). Results may inform school health programmes on the prevalence and correlates of bullying among adolescents in Thailand. PMID:23476124

Can Anal Sphincter Defects Be Identified by Palpation?

PubMed

Shek, Ka Lai; Atan, Ixora Kamisan; Dietz, Hans Peter

The aim of this study was to correlate clinical findings of anal sphincter defects and function with a sonographic diagnosis of significant sphincter defects. This is an observational cross-sectional study on women seen 6 to 10 weeks after primary repair of obstetric anal sphincter injuries (OASIs). All patients underwent a standardized interview including the St Mark incontinence score, a digital rectal examination, and 3-/4-dimensional transperineal ultrasound imaging. Two hundred forty-five patients were seen after primary repair of OASIs. Mean age was 29 (17-43) years. They were assessed at a median of 58 (15-278) days postpartum. One hundred fifty-seven (64%) delivered normal vaginally, 72 (29%) delivered by vacuum, and 16 (7%) delivered by forceps. A comparison of external anal sphincter (EAS) and internal anal sphincter ultrasound volume data and palpation was possible in 220 and 212 cases, respectively. Sphincter defects at rest and on contraction were both detected clinically in 17 patients. Significant abnormalities of the EAS were diagnosed on tomographic ultrasound imaging in 99 cases (45%), and significant abnormalities of the internal anal sphincter were diagnosed in 113 cases (53%). Agreement between digital and sonographic findings of sphincter defect was poor (k = 0.03-0.08). Women with significant EAS defects on ultrasound were found to have a lower resistance to digital insertion (P = 0.018) and maximum anal squeeze (P = 0.009) on a 6-point scale. The difference was however small. Digital rectal examination does not seem to be sufficiently sensitive to diagnose residual sphincter defects after primary repair of OASIs. Imaging is required for the evaluation of sphincter anatomy after repair.

Two growth mechanisms in one-step fabrication of the oxide matrix for FeSiAl soft magnetic composites

NASA Astrophysics Data System (ADS)

Wu, Chen; Gao, Xinwei; Zhao, Guoliang; Jiang, Yinzhu; Yan, Mi

2018-04-01

Hydrolysis precipitation as a new method was used in the preparation of oxide insulation matrix for FeSiAl soft magnetic composites (SMCs). The growth and composition of the matrix can be tuned by the concentration of the Al(NO3)3 solution, reaction temperature and pH value during the hydrolysis. With optimized Al(NO3)3 concentration of 0.6 mol/L and hydrolysis temperature of 75 °C, two mechanisms have been revealed in the formation of the insulation coating depending on the pH of the Al(NO3)3 solution. When pH = 3, the coating layer contains a mixture of Al2O3 and Fe2O3, while Al2O3 and SiO2 form as the coating for pH = 8. Despite that the Al2O3 dominates for both conditions, it grows via different routes. The Al(OH)3 as the precursor forms through Al3+ hydrolysis and heterogeneous nucleation for pH = 3. With increased pH to 8, the Al3+ directly reacts with OH- to form Al(OH)3 colloidal particles which adsorb onto the surface of FeSiAl powders via electrostatic attraction. Both mechanisms give rise to satisfactory magnetic performance with high effective permeability (μe = 103.5 and 113.4) and low core loss (Pcv = 278.4 mW·cm-3 and 237.8 mW·cm-3) for pH = 3 and 8 measured at 100 mT, 50 kHz.

Delirium in the geriatric unit: proton-pump inhibitors and other risk factors.

PubMed

Otremba, Iwona; Wilczyński, Krzysztof; Szewieczek, Jan

2016-01-01

Delirium remains a major nosocomial complication of hospitalized elderly. Predictive models for delirium may be useful for identification of high-risk patients for implementation of preventive strategies. Evaluate specific factors for development of delirium in a geriatric ward setting. Prospective cross-sectional study comprised 675 consecutive patients aged 79.2±7.7 years (66% women and 34% men), admitted to the subacute geriatric ward of a multiprofile university hospital after exclusion of 113 patients treated with antipsychotic medication because of behavioral disorders before admission. Comprehensive geriatric assessments including a structured interview, physical examination, geriatric functional assessment, blood sampling, ECG, abdominal ultrasound, chest X-ray, Confusion Assessment Method for diagnosis of delirium, Delirium-O-Meter to assess delirium severity, Richmond Agitation-Sedation Scale to assess sedation or agitation, visual analog scale and Doloplus-2 scale to assess pain level were performed. Multivariate logistic regression analysis revealed five independent factors associated with development of delirium in geriatric inpatients: transfer between hospital wards (odds ratio [OR] =2.78; confidence interval [CI] =1.54-5.01; P=0.001), preexisting dementia (OR =2.29; CI =1.44-3.65; P<0.001), previous delirium incidents (OR =2.23; CI =1.47-3.38; P<0.001), previous fall incidents (OR =1.76; CI =1.17-2.64; P=0.006), and use of proton-pump inhibitors (OR =1.67; CI =1.11-2.53; P=0.014). Transfer between hospital wards, preexisting dementia, previous delirium incidents, previous fall incidents, and use of proton-pump inhibitors are predictive of development of delirium in the geriatric inpatient setting.

Hospital volume and other risk factors for in-hospital mortality among diverticulitis patients: A nationwide analysis

PubMed Central

Diamant, Michael J; Coward, Stephanie; Buie, W Donald; MacLean, Anthony; Dixon, Elijah; Ball, Chad G; Schaffer, Samuel; Kaplan, Gilaad G

2015-01-01

BACKGROUND: Previous studies have found that a higher volume of colorectal surgery was associated with lower mortality rates. While diverticulitis is an increasingly common condition, the effect of hospital volume on outcomes among diverticulitis patients is unknown. OBJECTIVE: To evaluate the relationship between hospital volume and other factors on in-hospital mortality among patients admitted for diverticulitis. METHODS: Data from the Nationwide Inpatient Sample (years 1993 to 2008) were analyzed to identify 822,865 patients representing 4,108,726 admissions for diverticulitis. Hospitals were divided into quartiles based on the volume of diverticulitis cases admitted over the study period, adjusted for years contributed to the dataset. Mortality according to hospital volume was modelled using logistic regression adjusting for age, sex, race, comorbidities, health care insurance, admission type, calendar year, colectomy, disease severity and clustering. Risk estimates were expressed as adjusted ORs with 95% CIs. RESULTS: Patients at high-volume hospitals were more likely to be admitted emergently, undergo surgical treatment and have more severe disease. In-hospital mortality was higher among the lowest quartile of hospital volume compared with the highest volume (OR 1.13 [95% CI 1.05 to 1.21]). In-hospital mortality was increased among patients admitted emergently (OR 2.58 [95% CI 2.40 to 2.78]) as well as those receiving surgical treatment (OR 3.60 [95% CI 3.42 to 3.78]). CONCLUSIONS: Diverticulitis patients admitted to hospitals with a low volume of diverticulitis cases had an increased risk for death compared with those admitted to high-volume centres. PMID:25965439

Prevalence of mental disorders among depressed coronary patients with and without Type D personality. Results of the multi-center SPIRR-CAD trial.

PubMed

Lambertus, Frank; Herrmann-Lingen, Christoph; Fritzsche, Kurt; Hamacher, Stefanie; Hellmich, Martin; Jünger, Jana; Ladwig, Karl-Heinz; Michal, Matthias; Ronel, Joram; Schultz, Jobst-Hendrik; Vitinius, Frank; Weber, Cora; Albus, Christian

Type D personality, as with formal mental disorders, is linked to increased mortality in coronary heart disease (CHD). Our aim was to determine the prevalence of mental disorders among depressed CHD patients with and without Type D personality. Depressive symptoms (HADS, HAM-D), Type D personality (DS-14) and mental disorders based on DSM-IV (SCID I and II) were assessed. Results were calculated by Kruskal-Wallis tests, Fisher's exact tests and logistic regression analyses. 570 CHD patients were included (age 59.2±9.5years; male 78.9%, HADS-D depression 10.4±2.5; HAM-D 11.3±6.6; Type D 60.1%). 84.8% of patients with Type D personality and 79.3% of non-Type D patients suffered from at least one mental disorder (p=0.092), while 41.8% of Type D positives and 27.8% of Type D negatives had at least two mental disorders (p=0.001). Patients with Type D personality significantly more often had social phobia [odds ratio (95% confidence interval): 3.79 (1.1 to 13.12); p=0.035], dysthymia [1.78 (1.12 to 2.84); p=0.015], compulsive [2.25 (1.04 to 4.86); p=0.038] or avoidant [8.95 (2.08 to 38.49); p=0.003] personality disorder. Type D personality among depressed CHD patients is associated with more complex and enduring mental disorders. This implies higher treatment demands. ISRCTN 76240576; NCT00705965. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Scientific research in malaria: bibliometric assessment of the Latin-American contributions.

PubMed

Munoz-Urbano, Marcela; Lopez-Isaza, Andres F; Hurtado-Hurtado, Natalia; Gomez-Suta, Daniela; Murillo-Abadia, Jonathan; Delgado-Osorio, Nathalia; Lagos-Grisales, Guillermo J; Villegas, Soraya; Medina-Morales, Diego A; Rodriguez-Morales, Alfonso J

2014-01-01

Malaria is a parasitic disease of high global impact in public health, including Latin America. There should be more researched, particularly in this region. A bibliometric assessment of the Latin American contributions about malaria was done. Bibliometric study at SCI (1980-2013), MEDLINE/ GOPUBMED (1802-2013), Scopus (1959-2013), SCIELO (2004-2013), LILACS (1980-2013). The studies were characterized by study type, year of publication, city/country of origin, journals and more productive authors, citations and H index. At SCI, 2,806 articles were retrieved (5.13% of the total). Brazil was the highest producer (31.41%), followed by Colombia (14.3%) and Mexico (9.5%). The region received 39,894 citations, 32.2% from Brazil (H index=51), 12.75% Mexico (H index=38), 11.2% Colombia (H index=33). At Scopus, there are 4,150 articles (4.9% of the total), 33.0% Brazil, 11.3% Colombia and 8.8% Mexico; 17% in Brazil were from Universidad de São Paulo; 23.6% of Colombia from Universidad de Antioquia; 15.4% of Mexico from Instituto Nacional de Salud Pública. At Medline there were 4,278 records (36.8% Brazil). At SciELO there are 792 records (45.3% Brazil). At LILACS there were 1744 records (34.3% Brazil). Brazil has the highest output of the region, as Venezuela the scientific production in Malaria was related with the burden of disease. This was not the case for Colombia. Scientific production at bibliographical databases, particularly regionals, is low, compared to the high incidence of this disease that requires more research and control.

A retrospective and prospective analysis of trading sex for drugs or money in women substance abuse treatment patients.

PubMed

Rash, Carla J; Burki, Madison; Montezuma-Rusca, Jairo M; Petry, Nancy M

2016-05-01

Trading sex for drugs or money is common in substance abuse treatment patients, and this study evaluated prevalence and correlates of this behavior in women with cocaine use disorders initiating outpatient care. In addition, we examined the relation of sex trading status to treatment response in relation to usual care versus contingency management (CM), as well as predictors of continued involvement in sex trading over a 9-month period. Women (N=493) recruited from outpatient substance abuse treatment clinics were categorized according to histories of sex trading (n=215, 43.6%) or not (n=278). Women with a history of trading sex were more likely to be African American, older and less educated, and they had more severe employment problems and were more likely to be HIV positive than those without this history. Controlling for baseline differences, both groups responded equally to substance abuse treatment in terms of retention and abstinence outcomes. Fifty-four women (11.3%) reported trading sex within the next nine months. Predictors of continued involvement in trading sex included a prior history of such behaviors and achieving less abstinence during treatment. Each additional week of abstinence during treatment was associated with a 16% reduction in the likelihood of trading sex over the follow-up. Because over 40% of women receiving community-based treatment for cocaine use disorders have traded sex for drugs or money and more than 10% persist in the behavior, more intensive and directed approaches toward addressing this HIV risk behavior are recommended. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

49 CFR 385.113 - Administrative review.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 5 2010-10-01 2010-10-01 false Administrative review. 385.113 Section 385.113... Safety Monitoring System for Mexico-Domiciled Carriers § 385.113 Administrative review. (a) A Mexico-domiciled motor carrier may request the FMCSA to conduct an administrative review if it believes the FMCSA...

14 CFR 1245.113 - Hearing procedure.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Hearing procedure. 1245.113 Section 1245.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PATENTS AND OTHER INTELLECTUAL PROPERTY RIGHTS Patent Waiver Regulations § 1245.113 Hearing procedure. (a) If the petitioner requests an oral...

19 CFR 113.35 - Individual sureties.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 1 2012-04-01 2012-04-01 false Individual sureties. 113.35 Section 113.35 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS BONDS Principals and Sureties § 113.35 Individual sureties. (a) Number required. If individuals...

19 CFR 113.35 - Individual sureties.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Individual sureties. 113.35 Section 113.35 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS BONDS Principals and Sureties § 113.35 Individual sureties. (a) Number required. If individuals...

19 CFR 113.35 - Individual sureties.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 1 2013-04-01 2013-04-01 false Individual sureties. 113.35 Section 113.35 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS BONDS Principals and Sureties § 113.35 Individual sureties. (a) Number required. If individuals...

19 CFR 113.35 - Individual sureties.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 1 2011-04-01 2011-04-01 false Individual sureties. 113.35 Section 113.35 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS BONDS Principals and Sureties § 113.35 Individual sureties. (a) Number required. If individuals...

46 CFR 113.25-3 - Requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Requirements. 113.25-3 Section 113.25-3 Shipping COAST... SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-3 Requirements. Each vessel must have a general emergency alarm system that meets the requirements of this subpart. ...

46 CFR 113.25-3 - Requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Requirements. 113.25-3 Section 113.25-3 Shipping COAST... SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-3 Requirements. Each vessel must have a general emergency alarm system that meets the requirements of this subpart. ...

46 CFR 113.25-3 - Requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Requirements. 113.25-3 Section 113.25-3 Shipping COAST... SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-3 Requirements. Each vessel must have a general emergency alarm system that meets the requirements of this subpart. ...

5 CFR 550.113 - Computation of overtime pay.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Computation of overtime pay. 550.113 Section 550.113 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY ADMINISTRATION (GENERAL) Premium Pay Overtime Pay § 550.113 Computation of overtime pay. (a) For each employee...

10 CFR 1303.113 - Business information.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Business information. 1303.113 Section 1303.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.113 Business information. (a) In general. Business information obtained by the Board from a submitter shall be disclosed under the...

49 CFR 1.13 - OST Key Responsibilities.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 1 2013-10-01 2013-10-01 false OST Key Responsibilities. 1.13 Section 1.13... of the Secretary § 1.13 OST Key Responsibilities. (a) The OST is responsible for: (1) Providing... Government; (5) Encouraging maximum private development of transportation services; (6) Providing responsive...

49 CFR 1.13 - OST Key Responsibilities.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 1 2012-10-01 2012-10-01 false OST Key Responsibilities. 1.13 Section 1.13... of the Secretary § 1.13 OST Key Responsibilities. (a) The OST is responsible for: (1) Providing... Government; (5) Encouraging maximum private development of transportation services; (6) Providing responsive...

49 CFR 1.13 - OST Key Responsibilities.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 1 2014-10-01 2014-10-01 false OST Key Responsibilities. 1.13 Section 1.13... of the Secretary § 1.13 OST Key Responsibilities. (a) The OST is responsible for: (1) Providing... Government; (5) Encouraging maximum private development of transportation services; (6) Providing responsive...

46 CFR 113.27-1 - Engineers' assistance-needed alarm.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Engineers' assistance-needed alarm. 113.27-1 Section 113.27-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engineers' Assistance-Needed Alarm § 113.27-1 Engineers...

46 CFR 113.27-1 - Engineers' assistance-needed alarm.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Engineers' assistance-needed alarm. 113.27-1 Section 113.27-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engineers' Assistance-Needed Alarm § 113.27-1 Engineers...

46 CFR 113.27-1 - Engineers' assistance-needed alarm.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Engineers' assistance-needed alarm. 113.27-1 Section 113.27-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engineers' Assistance-Needed Alarm § 113.27-1 Engineers...

46 CFR 113.27-1 - Engineers' assistance-needed alarm.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Engineers' assistance-needed alarm. 113.27-1 Section 113.27-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engineers' Assistance-Needed Alarm § 113.27-1 Engineers...

46 CFR 113.27-1 - Engineers' assistance-needed alarm.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Engineers' assistance-needed alarm. 113.27-1 Section 113.27-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engineers' Assistance-Needed Alarm § 113.27-1 Engineers...

13 CFR 113.3-3 - Structural accommodations for handicapped clients.

Code of Federal Regulations, 2013 CFR

2013-01-01

... handicapped clients. 113.3-3 Section 113.3-3 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION... ADMINISTRATOR General Provisions § 113.3-3 Structural accommodations for handicapped clients. (a) Existing... by handicapped clients. Where structural changes are necessary to make the recipient's goods or...

13 CFR 113.3-3 - Structural accommodations for handicapped clients.

Code of Federal Regulations, 2012 CFR

2012-01-01

... handicapped clients. 113.3-3 Section 113.3-3 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION... ADMINISTRATOR General Provisions § 113.3-3 Structural accommodations for handicapped clients. (a) Existing... by handicapped clients. Where structural changes are necessary to make the recipient's goods or...

13 CFR 113.3-3 - Structural accommodations for handicapped clients.

Code of Federal Regulations, 2014 CFR

2014-01-01

... handicapped clients. 113.3-3 Section 113.3-3 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION... ADMINISTRATOR General Provisions § 113.3-3 Structural accommodations for handicapped clients. (a) Existing... by handicapped clients. Where structural changes are necessary to make the recipient's goods or...

13 CFR 113.3-3 - Structural accommodations for handicapped clients.

Code of Federal Regulations, 2010 CFR

2010-01-01

... handicapped clients. 113.3-3 Section 113.3-3 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION... ADMINISTRATOR General Provisions § 113.3-3 Structural accommodations for handicapped clients. (a) Existing... by handicapped clients. Where structural changes are necessary to make the recipient's goods or...

23 CFR 668.113 - Program and project procedures.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Program and project procedures. 668.113 Section 668.113 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS EMERGENCY RELIEF PROGRAM Procedures for Federal-Aid Highways § 668.113 Program and project procedures. (a...

10 CFR 1303.113 - Business information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Business information. 1303.113 Section 1303.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.113 Business information. (a) In general. Business information obtained by the Board from a submitter shall be disclosed under the...

7 CFR 1150.113 - Fluid milk products.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 9 2014-01-01 2013-01-01 true Fluid milk products. 1150.113 Section 1150.113... AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.113 Fluid milk products. Fluid milk products means those milk products normally...

7 CFR 1150.113 - Fluid milk products.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 9 2012-01-01 2012-01-01 false Fluid milk products. 1150.113 Section 1150.113... Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.113 Fluid milk products. Fluid milk products means those milk products normally...

7 CFR 1150.113 - Fluid milk products.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 9 2013-01-01 2013-01-01 false Fluid milk products. 1150.113 Section 1150.113... AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.113 Fluid milk products. Fluid milk products means those milk products normally...

29 CFR 1910.112-1910.113 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 5 2012-07-01 2012-07-01 false [Reserved] 1910.112-1910.113 Section 1910.112-1910.113 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR OCCUPATIONAL SAFETY AND HEALTH STANDARDS Hazardous Materials §§ 1910.112-1910.113...

10 CFR 71.113 - Document control.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Document control. 71.113 Section 71.113 Energy NUCLEAR....113 Document control. The licensee, certificate holder, and applicant for a CoC shall establish measures to control the issuance of documents such as instructions, procedures, and drawings, including...

10 CFR 71.113 - Document control.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Document control. 71.113 Section 71.113 Energy NUCLEAR....113 Document control. The licensee, certificate holder, and applicant for a CoC shall establish measures to control the issuance of documents such as instructions, procedures, and drawings, including...

10 CFR 71.113 - Document control.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Document control. 71.113 Section 71.113 Energy NUCLEAR....113 Document control. The licensee, certificate holder, and applicant for a CoC shall establish measures to control the issuance of documents such as instructions, procedures, and drawings, including...

46 CFR 113.50-1 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Applicability. 113.50-1 Section 113.50-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Public Address Systems § 113.50-1 Applicability. This subpart applies to each vessel...

46 CFR 113.37-1 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Applicability. 113.37-1 Section 113.37-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Shaft Speed and Thrust Indicators § 113.37-1 Applicability. This subpart applies to...

46 CFR 113.50-1 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Applicability. 113.50-1 Section 113.50-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Public Address Systems § 113.50-1 Applicability. This subpart applies to each vessel...

46 CFR 113.50-1 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Applicability. 113.50-1 Section 113.50-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Public Address Systems § 113.50-1 Applicability. This subpart applies to each vessel...

46 CFR 113.50-1 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Applicability. 113.50-1 Section 113.50-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Public Address Systems § 113.50-1 Applicability. This subpart applies to each vessel...

46 CFR 113.50-1 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Applicability. 113.50-1 Section 113.50-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Public Address Systems § 113.50-1 Applicability. This subpart applies to each vessel...

46 CFR 113.37-1 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Applicability. 113.37-1 Section 113.37-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Shaft Speed and Thrust Indicators § 113.37-1 Applicability. This subpart applies to...

46 CFR 113.37-1 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Applicability. 113.37-1 Section 113.37-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Shaft Speed and Thrust Indicators § 113.37-1 Applicability. This subpart applies to...

13 CFR 113.135 - Designation of responsible employee and adoption of grievance procedures.

Code of Federal Regulations, 2010 CFR

2010-01-01

... employee and adoption of grievance procedures. 113.135 Section 113.135 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NONDISCRIMINATION IN FINANCIAL ASSISTANCE PROGRAMS OF SBA-EFFECTUATION OF POLICIES... Programs or Activities Receiving Federal Financial Assistance Introduction § 113.135 Designation of...

49 CFR 229.113 - Warning notice.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Warning notice. 229.113 Section 229.113....113 Warning notice. Whenever any steam generator has been shut down because of defects, a distinctive warning notice giving reasons for the shut-down shall be conspicuously attached near the steam generator...

49 CFR 229.113 - Warning notice.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Warning notice. 229.113 Section 229.113....113 Warning notice. Whenever any steam generator has been shut down because of defects, a distinctive warning notice giving reasons for the shut-down shall be conspicuously attached near the steam generator...

49 CFR 229.113 - Warning notice.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Warning notice. 229.113 Section 229.113....113 Warning notice. Whenever any steam generator has been shut down because of defects, a distinctive warning notice giving reasons for the shut-down shall be conspicuously attached near the steam generator...

49 CFR 229.113 - Warning notice.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Warning notice. 229.113 Section 229.113....113 Warning notice. Whenever any steam generator has been shut down because of defects, a distinctive warning notice giving reasons for the shut-down shall be conspicuously attached near the steam generator...

49 CFR 229.113 - Warning notice.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Warning notice. 229.113 Section 229.113....113 Warning notice. Whenever any steam generator has been shut down because of defects, a distinctive warning notice giving reasons for the shut-down shall be conspicuously attached near the steam generator...

10 CFR 1303.113 - Business information.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Business information. 1303.113 Section 1303.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.113 Business information. (a) In general. Business information obtained by the Board from a submitter shall be disclosed under the...

10 CFR 1303.113 - Business information.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Business information. 1303.113 Section 1303.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.113 Business information. (a) In general. Business information obtained by the Board from a submitter shall be disclosed under the...

10 CFR 1303.113 - Business information.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Business information. 1303.113 Section 1303.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.113 Business information. (a) In general. Business information obtained by the Board from a submitter shall be disclosed under the...

7 CFR 1150.113 - Fluid milk products.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 9 2011-01-01 2011-01-01 false Fluid milk products. 1150.113 Section 1150.113... Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.113 Fluid milk products. Fluid milk products means those milk products normally...

7 CFR 1150.113 - Fluid milk products.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 9 2010-01-01 2009-01-01 true Fluid milk products. 1150.113 Section 1150.113... Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.113 Fluid milk products. Fluid milk products means those milk products normally...

46 CFR 113.35-1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Definitions. 113.35-1 Section 113.35-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-1 Definitions. As used in this subpart: (a...

21 CFR 113.60 - Containers.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Containers. 113.60 Section 113.60 Food and Drugs... CONSUMPTION THERMALLY PROCESSED LOW-ACID FOODS PACKAGED IN HERMETICALLY SEALED CONTAINERS Control of Components, Food Product Containers, Closures, and In-Process Materials § 113.60 Containers. (a) Closures...

21 CFR 113.60 - Containers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Containers. 113.60 Section 113.60 Food and Drugs... CONSUMPTION THERMALLY PROCESSED LOW-ACID FOODS PACKAGED IN HERMETICALLY SEALED CONTAINERS Control of Components, Food Product Containers, Closures, and In-Process Materials § 113.60 Containers. (a) Closures...

21 CFR 113.60 - Containers.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Containers. 113.60 Section 113.60 Food and Drugs... CONSUMPTION THERMALLY PROCESSED LOW-ACID FOODS PACKAGED IN HERMETICALLY SEALED CONTAINERS Control of Components, Food Product Containers, Closures, and In-Process Materials § 113.60 Containers. (a) Closures...

21 CFR 113.60 - Containers.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Containers. 113.60 Section 113.60 Food and Drugs... CONSUMPTION THERMALLY PROCESSED LOW-ACID FOODS PACKAGED IN HERMETICALLY SEALED CONTAINERS Control of Components, Food Product Containers, Closures, and In-Process Materials § 113.60 Containers. Link to an...

21 CFR 113.60 - Containers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Containers. 113.60 Section 113.60 Food and Drugs... CONSUMPTION THERMALLY PROCESSED LOW-ACID FOODS PACKAGED IN HERMETICALLY SEALED CONTAINERS Control of Components, Food Product Containers, Closures, and In-Process Materials § 113.60 Containers. (a) Closures...

18 CFR 401.113 - Segregable materials.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Segregable materials. 401.113 Section 401.113 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Public Access to Records and Information § 401.113...

46 CFR 113.37-1 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Applicability. 113.37-1 Section 113.37-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Shaft Speed and Thrust Indicators § 113.37-1 Applicability. This subpart applies to...

46 CFR 113.37-1 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Applicability. 113.37-1 Section 113.37-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Shaft Speed and Thrust Indicators § 113.37-1 Applicability. This subpart applies to...

46 CFR 113.37-10 - Detailed requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Detailed requirements. 113.37-10 Section 113.37-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Shaft Speed and Thrust Indicators § 113.37-10 Detailed requirements. (a...

46 CFR 113.37-10 - Detailed requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Detailed requirements. 113.37-10 Section 113.37-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Shaft Speed and Thrust Indicators § 113.37-10 Detailed requirements. (a...

14 CFR 13.113 - Noncompliance with the investigative process.

Code of Federal Regulations, 2010 CFR

2010-01-01

... process. 13.113 Section 13.113 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... an Order of Investigation § 13.113 Noncompliance with the investigative process. If any person fails... Officer or the designee of the Presiding Officer, judicial enforcement may be initiated against that...

High Level Expression and Purification of the Clinically Active Antimicrobial Peptide P-113 in Escherichia coli.

PubMed

Cheng, Kuang-Ting; Wu, Chih-Lung; Yip, Bak-Sau; Yu, Hui-Yuan; Cheng, Hsi-Tsung; Chih, Ya-Han; Cheng, Jya-Wei

2018-03-30

P-113, which was originally derived from the human saliva protein histatin 5, is a histidine-rich antimicrobial peptide with the sequence AKRHHGYKRKFH. P-113 is currently undergoing phase II clinical trial as a pharmaceutical agent to fight against fungal infections in HIV patients with oral candidiasis. Previously, we developed a new procedure for the high-yield expression and purification of hG31P, an analogue and antagonist of human CXCL8. Moreover, we have successfully removed lipopolysaccharide (LPS, endotoxin) associated with hG31P in the expression with Escherichia coli . In this paper, we have used hG31P as a novel fusion protein for the expression and purification of P-113. The purity of the expressed P-113 is more than 95% and the yield is 4 mg P-113 per liter of E. coli cell culture in Luria-Bertani (LB) medium. The antimicrobial activity of the purified P-113 was tested. Furthermore, we used circular dichroism (CD) and nuclear magnetic resonance (NMR) spectroscopy to study the structural properties of P-113. Our results indicate that using hG31P as a fusion protein to obtain large quantities of P-113 is feasible and is easy to scale up for commercial production. An effective way of producing enough P-113 for future clinical studies is evident in this study.

A Novel Soybean ERF Transcription Factor, GmERF113, Increases Resistance to Phytophthora sojae Infection in Soybean

PubMed Central

Zhao, Yuanling; Chang, Xin; Qi, Dongyue; Dong, Lidong; Wang, Guangjin; Fan, Sujie; Jiang, Liangyu; Cheng, Qun; Chen, Xi; Han, Dan; Xu, Pengfei; Zhang, Shuzhen

2017-01-01

Phytophthora root and stem rot of soybean caused by the oomycete Phytophthora sojae, is a destructive disease worldwide. Ethylene response factors (ERFs) play important roles in regulating plant biotic and abiotic stress tolerance. In this study, a new ERF gene, GmERF113, was isolated from the highly resistant soybean ‘Suinong 10.’ Sequence analysis suggested that the protein encoded by GmERF113 contained a conserved AP2/ERF domain of 58 amino acid and belonged to the B-4 subgroup of the ERF subfamily. Expression of GmERF113 was significantly induced by P. sojae, ethylene, and methyl jasmonate. GmERF113 protein localized to the nucleus when transiently expressed in Arabidopsis protoplasts, could bind to the GCC-box, and acted as a transcription activator. In addition, a region of the full-length GmERF113, GmERF113-II, interacted with a basic helix-loop-helix transcription factor (GmbHLH) in yeast cells. Full-length GmERF113 also interacted with GmbHLH in planta. GmERF113-overexpressing transgenic plants in susceptible cultivar ‘Dongnong 50’ soybean exhibited increased resistance to P. sojae and positively regulated the expression of the pathogenesis-related genes, PR1 and PR10-1. These results indicate that GmERF113 may play a crucial role in the defense of soybean against P. sojae infection. PMID:28326092

Selective Oxidation and Reactive Wetting During Hot-Dip Galvanizing of a 1.0 pct Al-0.5 pct Si TRIP-Assisted Steel

NASA Astrophysics Data System (ADS)

Bellhouse, E. M.; McDermid, J. R.

2012-07-01

Selective oxidation and reactive wetting during continuous galvanizing were studied for a low-alloy transformation induced plasticity (TRIP)-assisted steel with 0.2 pct C, 1.5 pct Mn, 1.0 pct Al and 0.5 pct Si. Three process atmospheres were tested during annealing prior to galvanizing: 220 K (-53 °C) dew point (dp) N2-20 pct H2, 243 K (-30 °C) dp N2-5 pct H2 and 278 K (+5 °C) dp N2-5 pct H2. The process atmosphere oxygen partial pressure affected the oxide chemistry, morphology and thickness. For the 220 K (-53 °C) dp and 243 K (-30 °C) dp process atmospheres, film and nodule-type manganese, silicon and aluminum containing oxides were observed at the surface. For the 278 K (+5 °C) dp atmosphere, MnO was observed at the grain boundaries and as thicker localized surface films. Oxide morphology, thickness and chemistry affected reactive wetting, with complete wetting being observed for the 220 K (-53 °C) dp and 243 K (-30 °C) dp process atmospheres and incomplete reactive wetting being observed for the 278 K (+5 °C) dp atmosphere. Complete reactive wetting for the 220 K (-53 °C) dp and 243 K (-30 °C) dp process atmospheres was attributed to a combination of zinc bridging of oxides, aluminothermic reduction of surface oxides and wetting of the oxides. Incomplete wetting for the 278 K (+5 °C) dp atmosphere was attributed to localized thick MnO films.

Serum alkaline phosphatase as a predictor of worsening renal function in patients with acute decompensated heart failure.

PubMed

Yamazoe, Masahiro; Mizuno, Atsushi; Nishi, Yutaro; Niwa, Koichiro; Isobe, Mitsuaki

2016-05-01

Venous congestion has come into focus as an important hemodynamic factor for worsening renal function (WRF) in patients with acute decompensated heart failure (ADHF). Serum alkaline phosphatase (ALP) was reported as a biological marker of liver congestion in ADHF. The purpose of this study was to determine whether ALP is a predictor of WRF in patients with ADHF. We enrolled consecutive patients admitted to a single cardiovascular center with ADHF, and defined WRF as an increase in creatinine of >0.3 mg/dl during hospitalization and chronic kidney disease (CKD) as an estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m(2). The patients were classified into tertiles by ALP level (<203, 203-278, and >278 IU/L). A total of 972 patients (mean age, 76±13 years; 54% male) were retrospectively analyzed. WRF was identified in 132 patients (13.6%). In multivariate logistic regression analysis, baseline CKD [odds ratio (OR) 2.46, 95% confidence interval (CI) 1.48-4.08, p<0.001], serum albumin (OR 0.52, 95% CI 0.35-0.77, p=0.001), and diabetes (OR 2.07, 95% CI 1.37-3.12, p<0.001) were associated with WRF. Compared with the lowest tertile (ALP <203 IU/L), an adjusted OR of WRF was 1.69 (95% CI 1.02-2.79, p=0.04) in the middle tertile (ALP, 203-278 IU/L) and 1.95 (95% CI 1.20-3.21, p=0.008) in the highest tertile (ALP >278 IU/L). Serum ALP is an independent predictor of WRF in the clinical course of ADHF. Copyright © 2015 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.

Binding-, intracellular transport-, and biosynthesis-defective mutants of vasopressin type 2 receptor in patients with X-linked nephrogenic diabetes insipidus.

PubMed Central

Tsukaguchi, H; Matsubara, H; Taketani, S; Mori, Y; Seido, T; Inada, M

1995-01-01

Nephrogenic diabetes insipidus (NDI) is most often an X-linked disorder in which urine is not concentrated due to renal resistance to arginine vasopressin. We recently identified four vasopressin type 2 receptor gene mutations in unrelated X-linked NDI families, including R143P, delta V278, R202C, and 804insG. All these mutations reduced ligand binding activity to < 10% of the normal without affecting mRNA accumulation. To elucidate whether the receptors are expressed on the cell surface, we analyzed biosynthesis and localization of tagged or untagged receptors stably expressed in Chinese hamster ovary (CHO) cells, using two antibodies directed against distinct termini. Whole-cell and surface labeling studies revealed that the R202C clone had both surface-localized (50-55 kD) and intracellular proteins (40 and 75 kD), similar to the wild-type AVPR2 clone, whereas the R143P and delta V278 clones lacked the surface receptors, despite relatively increased intracellular components. The 804insG mutant cell produced no proteins despite an adequate mRNA level. Immunofluorescence staining confirmed that the R202C mutant reaches the cell surface, whereas the R143P and delta V278 mutants are retained within the cytoplasmic compartment. Thus, R202C, R143P/delta V278, and 804insG result in three distinct phenotypes, that is, a simple binding impairment at the cell surface, blocked intracellular transport, and ineffective biosynthesis or/and accelerated degradation of the receptor, respectively, and therefore are responsible for NDI. This phenotypic classification will help understanding of molecular pathophysiology of this disorder. Images PMID:7560098

A comparative study of nutritional status and foodstuffs in adolescent girls in iran.

PubMed

Talaie-Zanjani, A; Faraji, F; Rafie, M; Mohammadbeigi, A

2014-01-01

The prevalence of obesity and overweight in children and adolescents is increasing world-wide. Obesity in children and adolescents is a major risk factor for diabetes, heart diseases, hypertension, and cancer in adulthood. The aim of the study was to compare the nutritional status and food-stuffs among high-school girls in Arak, Iran, in matter of body mass index (BMI) and associated factors. A cross-sectional survey of a representative sample of 278 adolescents was conducted in six randomly chosen high-schools. Height and weight of students were collected using standard methods and the BMI calculated and BMI percentiles of these girls are compared with the Center of Disease Control and Prevention (CDC) reference data. The 5(th), 8(th), and 95(th) percentiles of the CDC were adopted as cut-off points for underweight, overweight and obese girls, respectively. Data were analyzed using SPSS by analysis of variance and Chi-square tests. On the basis of CDC, the overall prevalence rates of underweight, overweight, and obesity were estimated 10.1% (28/278), 12.9% (36/278), and 1.4% (4/278), respectively. There was no significant difference between nutritional knowledge scores and the rate of physical activities in various groups. The mean age at menarche was significantly higher among the obese girls (P = 0.02). Consumption of ice-cream and chocolate was significantly higher in the obese girls group (P = 0.03). According to the present study, the prevalence of overweight and obesity in high-school girls of Arak is lower than that of many other parts of Iran and some neighboring countries, which are at the high-risk of overweight and obesity. This study warrants the necessity of paying attention to promote healthy life-style and weight control. The earlier age of menarche is alarming.

Early Cretaceous bimodal volcanism in the Duolong Cu mining district, western Tibet: Record of slab breakoff that triggered ca. 108-113 Ma magmatism in the western Qiangtang terrane

NASA Astrophysics Data System (ADS)

Wei, Shao-gang; Tang, Ju-xing; Song, Yang; Liu, Zhi-bo; Feng, Jun; Li, Yan-bo

2017-05-01

We report new zircon U-Pb ages and Hf isotope compositions, and whole-rock major and trace element and Sr-Nd isotope data for the Meiriqiecuo Formation (MF) bimodal volcanic rocks collected from the Duolong Cu mining district (DCMD) in the western Qiangtang terrane (QT), western Tibet. These data provide important constraints on the petrogenetic evolution and geodynamic setting of Early Cretaceous magmatism in the DCMD. The MF bimodal volcanic rocks are mainly basaltic andesite and andesite, with subordinate rhyolite. Four mafic samples yielded zircon U-Pb ages of ca. 108.2-113.0 Ma, and one silicic sample has an age of 109.3 ± 2.2 Ma, indicating that the mafic and silicic eruptions were contemporaneous. The MF bimodal volcanic rocks belong to the medium-K calc-alkaline to shoshonite series. The rocks show arc-type affinities characterized by significant enrichment in light rare earth (LaN/YbN = 7.74-12.60) and large-ion lithophile elements (Rb, Cs, K, and Pb), but depletions in the high-field-strength elements (Nb, Ta, and Ti), which geochemically resemble Andean arc basalts. Therefore, the MF bimodal volcanic rocks were likely emplaced at an Andean-type active continental margin and represent an Early Cretaceous magmatic arc that was located at the western QT margin. Moreover, the mafic volcanic rocks have high initial Sr isotopic ratios (0.705269-0.705413) and negative εNd(t) values of -1.5 to -0.6 compared with the silicic volcanic rocks ((87Sr/86Sr)i = 0.704770-0.704903; εNd(t) = +1.2 to +1.3). Zircons from silicic samples have significantly higher εHf(t) values (+11.6 to +15.5) and predominantly lower Paleoproterozoic Hf crustal model ages (TDMC = 180-428 Ma) than the mafic samples, which have variable εHf(t) values of +3.4 to +13.0 and TDMC ages of 346-952 Ma. These results indicate that the mafic and silicic end-members of the MF bimodal suite were generated from mantle and crustal sources, respectively. The basaltic andesite and andesite may have been derived from mantle enriched by the metasomatism of subducted fluids, whereas the rhyolite could have been derived by partial melting of mafic juvenile crust that originated from an older and more depleted mantle. In light of the geochemical characteristics and field relationships, we propose that breakoff of the Bangong-Nujiang oceanic lithosphere was responsible for the generation and emplacement of the MF bimodal volcanic rocks. The fact that the MF bimodal volcanic arc magmatism was active at ca. 108-113 Ma indicates that it was associated with closure of the Bangong-Nujiang Ocean via an arc-arc "soft" collision during the Early Cretaceous.

Construction and validation of a three-dimensional finite element model of degenerative scoliosis.

PubMed

Zheng, Jie; Yang, Yonghong; Lou, Shuliang; Zhang, Dongsheng; Liao, Shenghui

2015-12-24

With the aging of the population, degenerative scoliosis (DS) incidence rate is increasing. In recent years, increasing research on this topic has been carried out, yet biomechanical research on the subject is seldom seen and in vitro biomechanical model of DS nearly cannot be available. The objective of this study was to develop and validate a complete three-dimensional finite element model of DS in order to build the digital platform for further biomechanical study. A 55-year-old female DS patient (Suer Pan, ID number was P141986) was selected for this study. This study was performed in accordance with the ethical standards of Declaration of Helsinki and its amendments and was approved by the local ethics committee (117 hospital of PLA ethics committee). Spiral computed tomography (CT) scanning was conducted on the patient's lumbar spine from the T12 to S1. CT images were then imported into a finite element modeling system. A three-dimensional solid model was then formed from segmentation of the CT scan. The three-dimensional model of each vertebra was then meshed, and material properties were assigned to each element according to the pathological characteristics of DS. Loads and boundary conditions were then applied in such a manner as to simulate in vitro biomechanical experiments conducted on lumbar segments. The results of the model were then compared with experimental results in order to validate the model. An integral three-dimensional finite element model of DS was built successfully, consisting of 113,682 solid elements, 686 cable elements, 33,329 shell elements, 4968 target elements, 4968 contact elements, totaling 157,635 elements, and 197,374 nodes. The model accurately described the physical features of DS and was geometrically similar to the object of study. The results of analysis with the finite element model agreed closely with in vitro experiments, validating the accuracy of the model. The three-dimensional finite element model of DS built in this study is clear, reliable, and effective for further biomechanical simulation study of DS.

46 CFR 113.10-5 - Common return.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Common return. 113.10-5 Section 113.10-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-5 Common return. A conductor...

9 CFR 113.3 - Sampling of biological products.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Sampling of biological products. 113.3 Section 113.3 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... Applicability § 113.3 Sampling of biological products. Each licensee and permittee shall furnish representative...

9 CFR 113.3 - Sampling of biological products.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Sampling of biological products. 113.3 Section 113.3 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... Applicability § 113.3 Sampling of biological products. Each licensee and permittee shall furnish representative...

32 CFR 219.113 - Suspension or termination of IRB approval of research.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Suspension or termination of IRB approval of research. 219.113 Section 219.113 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PROTECTION OF HUMAN SUBJECTS § 219.113 Suspension or...

48 CFR 18.113 - Interagency acquisitions under the Economy Act.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Interagency acquisitions under the Economy Act. 18.113 Section 18.113 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES EMERGENCY ACQUISITIONS Available Acquisition Flexibilities 18.113 Interagency acquisitions under...

16 CFR 1028.113 - Suspension or termination of IRB approval of research.

Code of Federal Regulations, 2010 CFR

2010-01-01

... research. 1028.113 Section 1028.113 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL PROTECTION OF HUMAN SUBJECTS § 1028.113 Suspension or termination of IRB approval of research. An IRB shall... with the IRB's requirements or that has been associated with unexpected serious harm to subjects. Any...

46 CFR 113.30-5 - Requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Requirements. 113.30-5 Section 113.30-5 Shipping COAST... SYSTEMS AND EQUIPMENT Internal Communications § 113.30-5 Requirements. (a) Communication. Each vessel must... finder. Communication to the radio and radio direction finder must meet the following requirements: (1...

46 CFR 113.30-5 - Requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Requirements. 113.30-5 Section 113.30-5 Shipping COAST... SYSTEMS AND EQUIPMENT Internal Communications § 113.30-5 Requirements. (a) Communication. Each vessel must... finder. Communication to the radio and radio direction finder must meet the following requirements: (1...

46 CFR 113.30-5 - Requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Requirements. 113.30-5 Section 113.30-5 Shipping COAST... SYSTEMS AND EQUIPMENT Internal Communications § 113.30-5 Requirements. (a) Communication. Each vessel must... finder. Communication to the radio and radio direction finder must meet the following requirements: (1...

14 CFR 1215.113 - User charges.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false User charges. 1215.113 Section 1215.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION TRACKING AND DATA RELAY SATELLITE SYSTEM (TDRSS) Use and Reimbursement Policy for Non-U.S. Government Users § 1215.113 User charges. (a) The user...

14 CFR 1215.113 - User charges.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true User charges. 1215.113 Section 1215.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION TRACKING AND DATA RELAY SATELLITE SYSTEM (TDRSS) Use and Reimbursement Policy for Non-U.S. Government Users § 1215.113 User charges. (a) The user...

78 FR 56148 - Airworthiness Directives; Bell Helicopter Textron Canada Limited (Bell) Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-12

... Assembly Engine Bipod Mount, P/N 230-060-113-101, 230-060-113-102, 230-060-114-101, or 230-060-114-102... 430 with (i) Fitting Assembly Engine Bipod Mount, P/N 230-060-113-101, 230-060-113-102, 230-060-114...

6 CFR 11.3 - Demand for payment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 6 Domestic Security 1 2010-01-01 2010-01-01 false Demand for payment. 11.3 Section 11.3 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CLAIMS § 11.3 Demand for payment. (a) Notice requirements. Generally, before DHS starts the collection actions described in this subpart, DHS...

49 CFR 194.113 - Information summary.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 3 2013-10-01 2013-10-01 false Information summary. 194.113 Section 194.113... Response Plans § 194.113 Information summary. (a) The information summary for the core plan, required by... state(s). (b) The information summary for the response zone appendix, required in § 194.107, must...

46 CFR 16.113 - Chemical drug testing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Chemical drug testing. 16.113 Section 16.113 Shipping... General § 16.113 Chemical drug testing. (a) Drug testing programs required by this part must be conducted... should be consulted to determine the specific procedures which must be established and utilized. Drug...

46 CFR 16.113 - Chemical drug testing.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 1 2014-10-01 2014-10-01 false Chemical drug testing. 16.113 Section 16.113 Shipping... General § 16.113 Chemical drug testing. (a) Drug testing programs required by this part must be conducted... should be consulted to determine the specific procedures which must be established and utilized. Drug...

46 CFR 16.113 - Chemical drug testing.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Chemical drug testing. 16.113 Section 16.113 Shipping... General § 16.113 Chemical drug testing. (a) Drug testing programs required by this part must be conducted... should be consulted to determine the specific procedures which must be established and utilized. Drug...

46 CFR 16.113 - Chemical drug testing.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Chemical drug testing. 16.113 Section 16.113 Shipping... General § 16.113 Chemical drug testing. (a) Drug testing programs required by this part must be conducted... should be consulted to determine the specific procedures which must be established and utilized. Drug...

46 CFR 16.113 - Chemical drug testing.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Chemical drug testing. 16.113 Section 16.113 Shipping... General § 16.113 Chemical drug testing. (a) Drug testing programs required by this part must be conducted... should be consulted to determine the specific procedures which must be established and utilized. Drug...

46 CFR 113.25-6 - Power supply.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Power supply. 113.25-6 Section 113.25-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-6 Power supply. The emergency power source...

46 CFR 113.25-6 - Power supply.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Power supply. 113.25-6 Section 113.25-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-6 Power supply. The emergency power source...

46 CFR 113.43-5 - Power supply.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Power supply. 113.43-5 Section 113.43-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Steering Failure Alarm Systems § 113.43-5 Power supply. Each steering failure alarm...

46 CFR 113.43-5 - Power supply.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Power supply. 113.43-5 Section 113.43-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Steering Failure Alarm Systems § 113.43-5 Power supply. Each steering failure alarm...

46 CFR 113.25-6 - Power supply.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Power supply. 113.25-6 Section 113.25-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-6 Power supply. The emergency power source...

46 CFR 113.43-5 - Power supply.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Power supply. 113.43-5 Section 113.43-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Steering Failure Alarm Systems § 113.43-5 Power supply. Each steering failure alarm...

21 CFR 133.113 - Cheddar cheese.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Cheddar cheese. 133.113 Section 133.113 Food and... CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific Standardized Cheese and Related Products § 133.113 Cheddar cheese. (a) Description. (1) Cheddar cheese is the food prepared by the...

21 CFR 133.113 - Cheddar cheese.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Cheddar cheese. 133.113 Section 133.113 Food and... CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific Standardized Cheese and Related Products § 133.113 Cheddar cheese. (a) Description. (1) Cheddar cheese is the food prepared by the...

46 CFR 113.25-12 - Alarm signals.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Alarm signals. 113.25-12 Section 113.25-12 Shipping... SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-12 Alarm signals. (a) Each general emergency alarm signal must be an electrically-operated bell, klaxon, or other warning device capable of...

46 CFR 113.25-12 - Alarm signals.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Alarm signals. 113.25-12 Section 113.25-12 Shipping... SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-12 Alarm signals. (a) Each general emergency alarm signal must be an electrically-operated bell, klaxon, or other warning device capable of...

9 CFR 113.55 - Detection of extraneous agents in Master Seed Virus.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Master Seed Virus. 113.55 Section 113.55 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Ingredient Requirements § 113.55 Detection of extraneous agents in Master Seed Virus...

9 CFR 113.55 - Detection of extraneous agents in Master Seed Virus.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Master Seed Virus. 113.55 Section 113.55 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Ingredient Requirements § 113.55 Detection of extraneous agents in Master Seed Virus...

9 CFR 113.55 - Detection of extraneous agents in Master Seed Virus.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Master Seed Virus. 113.55 Section 113.55 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Ingredient Requirements § 113.55 Detection of extraneous agents in Master Seed Virus...

9 CFR 113.55 - Detection of extraneous agents in Master Seed Virus.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Master Seed Virus. 113.55 Section 113.55 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Ingredient Requirements § 113.55 Detection of extraneous agents in Master Seed Virus...

46 CFR 169.113 - Right of appeal.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Right of appeal. 169.113 Section 169.113 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS General Provisions § 169.113 Right of appeal. Any person directly affected by a decision or action taken under this...

7 CFR 1955.113 - Price (housing).

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 14 2010-01-01 2009-01-01 true Price (housing). 1955.113 Section 1955.113 Agriculture... § 1955.113 Price (housing). Real property will be offered or listed for its present market value, as adjusted by any administrative price reductions provided for in this section. Market value will be based...

21 CFR 20.113 - Voluntary product defect reports.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Voluntary product defect reports. 20.113 Section 20.113 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.113 Voluntary product defect...

23 CFR 660.113 - Construction.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Construction. 660.113 Section 660.113 Highways FEDERAL... (DIRECT FEDERAL) Forest Highways § 660.113 Construction. (a) No construction shall be undertaken on any FH... construction of FHs will be performed by the contract method, unless construction by the FHWA, the FS, or a...

23 CFR 660.113 - Construction.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false Construction. 660.113 Section 660.113 Highways FEDERAL... (DIRECT FEDERAL) Forest Highways § 660.113 Construction. (a) No construction shall be undertaken on any FH... construction of FHs will be performed by the contract method, unless construction by the FHWA, the FS, or a...

23 CFR 660.113 - Construction.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 23 Highways 1 2012-04-01 2012-04-01 false Construction. 660.113 Section 660.113 Highways FEDERAL... (DIRECT FEDERAL) Forest Highways § 660.113 Construction. (a) No construction shall be undertaken on any FH... construction of FHs will be performed by the contract method, unless construction by the FHWA, the FS, or a...

23 CFR 660.113 - Construction.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false Construction. 660.113 Section 660.113 Highways FEDERAL... (DIRECT FEDERAL) Forest Highways § 660.113 Construction. (a) No construction shall be undertaken on any FH... construction of FHs will be performed by the contract method, unless construction by the FHWA, the FS, or a...

23 CFR 660.113 - Construction.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Construction. 660.113 Section 660.113 Highways FEDERAL... (DIRECT FEDERAL) Forest Highways § 660.113 Construction. (a) No construction shall be undertaken on any FH... construction of FHs will be performed by the contract method, unless construction by the FHWA, the FS, or a...

46 CFR 113.10-5 - Common return.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Common return. 113.10-5 Section 113.10-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-5 Common return. A conductor...

46 CFR 113.10-7 - Connection boxes.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Connection boxes. 113.10-7 Section 113.10-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-7 Connection boxes. Each...

46 CFR 113.10-1 - Approved equipment.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Approved equipment. 113.10-1 Section 113.10-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-1 Approved equipment. Each alarm...

46 CFR 113.10-7 - Connection boxes.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Connection boxes. 113.10-7 Section 113.10-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-7 Connection boxes. Each...

46 CFR 113.10-5 - Common return.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Common return. 113.10-5 Section 113.10-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-5 Common return. A conductor...

46 CFR 113.10-1 - Approved equipment.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Approved equipment. 113.10-1 Section 113.10-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-1 Approved equipment. Each alarm...

46 CFR 113.10-1 - Approved equipment.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Approved equipment. 113.10-1 Section 113.10-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-1 Approved equipment. Each alarm...

46 CFR 113.10-3 - Cable runs.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Cable runs. 113.10-3 Section 113.10-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-3 Cable runs. Cable runs between...

46 CFR 113.10-5 - Common return.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Common return. 113.10-5 Section 113.10-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-5 Common return. A conductor...

46 CFR 113.10-7 - Connection boxes.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Connection boxes. 113.10-7 Section 113.10-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-7 Connection boxes. Each...

46 CFR 113.10-7 - Connection boxes.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Connection boxes. 113.10-7 Section 113.10-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-7 Connection boxes. Each...

46 CFR 113.10-3 - Cable runs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Cable runs. 113.10-3 Section 113.10-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-3 Cable runs. Cable runs between...

46 CFR 113.10-3 - Cable runs.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Cable runs. 113.10-3 Section 113.10-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-3 Cable runs. Cable runs between...

46 CFR 113.10-3 - Cable runs.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Cable runs. 113.10-3 Section 113.10-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-3 Cable runs. Cable runs between...

46 CFR 113.10-5 - Common return.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Common return. 113.10-5 Section 113.10-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-5 Common return. A conductor...

46 CFR 113.10-1 - Approved equipment.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Approved equipment. 113.10-1 Section 113.10-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-1 Approved equipment. Each alarm...

46 CFR 113.10-7 - Connection boxes.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Connection boxes. 113.10-7 Section 113.10-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-7 Connection boxes. Each...

46 CFR 113.10-1 - Approved equipment.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Approved equipment. 113.10-1 Section 113.10-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-1 Approved equipment. Each alarm...

12 CFR 1815.113 - Public involvement.

Code of Federal Regulations, 2011 CFR

2011-01-01

... ENVIRONMENTAL QUALITY § 1815.113 Public involvement. All information collected by the Fund pursuant to this part shall be available to the public consistent with the CEQ regulations. Interested persons may obtain... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Public involvement. 1815.113 Section 1815.113...

12 CFR 1815.113 - Public involvement.

Code of Federal Regulations, 2014 CFR

2014-01-01

... ENVIRONMENTAL QUALITY § 1815.113 Public involvement. All information collected by the Fund pursuant to this part shall be available to the public consistent with the CEQ regulations. Interested persons may obtain... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Public involvement. 1815.113 Section 1815.113...

12 CFR 1815.113 - Public involvement.

Code of Federal Regulations, 2012 CFR

2012-01-01

... ENVIRONMENTAL QUALITY § 1815.113 Public involvement. All information collected by the Fund pursuant to this part shall be available to the public consistent with the CEQ regulations. Interested persons may obtain... 12 Banks and Banking 9 2012-01-01 2012-01-01 false Public involvement. 1815.113 Section 1815.113...

12 CFR 1815.113 - Public involvement.

Code of Federal Regulations, 2010 CFR

2010-01-01

... ENVIRONMENTAL QUALITY § 1815.113 Public involvement. All information collected by the Fund pursuant to this part shall be available to the public consistent with the CEQ regulations. Interested persons may obtain... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Public involvement. 1815.113 Section 1815.113...

12 CFR 1815.113 - Public involvement.

Code of Federal Regulations, 2013 CFR

2013-01-01

... ENVIRONMENTAL QUALITY § 1815.113 Public involvement. All information collected by the Fund pursuant to this part shall be available to the public consistent with the CEQ regulations. Interested persons may obtain... 12 Banks and Banking 9 2013-01-01 2013-01-01 false Public involvement. 1815.113 Section 1815.113...

40 CFR 35.113 - Reimbursement for pre-award costs.

Code of Federal Regulations, 2011 CFR

2011-07-01

....113 Section 35.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Environmental Program Grants Epa Action on Application § 35.113 Reimbursement for pre-award costs. (a) Notwithstanding the requirements of 40 CFR 31.23(a) and OMB cost...

40 CFR 35.113 - Reimbursement for pre-award costs.

Code of Federal Regulations, 2010 CFR

2010-07-01

....113 Section 35.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Environmental Program Grants Epa Action on Application § 35.113 Reimbursement for pre-award costs. (a) Notwithstanding the requirements of 40 CFR 31.23(a) and OMB cost...

46 CFR 113.35-9 - Mechanical engine order telegraph systems.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Mechanical engine order telegraph systems. 113.35-9 Section 113.35-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-9 Mechanical engine order...

46 CFR 113.35-9 - Mechanical engine order telegraph systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Mechanical engine order telegraph systems. 113.35-9 Section 113.35-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-9 Mechanical engine order...

46 CFR 113.35-9 - Mechanical engine order telegraph systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Mechanical engine order telegraph systems. 113.35-9 Section 113.35-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-9 Mechanical engine order...

46 CFR 113.35-9 - Mechanical engine order telegraph systems.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Mechanical engine order telegraph systems. 113.35-9 Section 113.35-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-9 Mechanical engine order...

40 CFR 113.6 - Effect on other laws.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 22 2011-07-01 2011-07-01 false Effect on other laws. 113.6 Section 113.6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.6 Effect on other laws. Nothing...

40 CFR 113.6 - Effect on other laws.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 23 2013-07-01 2013-07-01 false Effect on other laws. 113.6 Section 113.6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.6 Effect on other laws. Nothing...

40 CFR 113.6 - Effect on other laws.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Effect on other laws. 113.6 Section 113.6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.6 Effect on other laws. Nothing...

41 CFR 109-40.113 - Insurance against transportation hazards.

Code of Federal Regulations, 2012 CFR

2012-01-01

... transportation hazards. 109-40.113 Section 109-40.113 Public Contracts and Property Management Federal Property..., TRANSPORTATION, AND MOTOR VEHICLES 40-TRANSPORTATION AND TRAFFIC MANAGEMENT 40.1-General Provision § 109-40.113 Insurance against transportation hazards. The policy of the Government with respect to insurance of its...

41 CFR 109-40.113 - Insurance against transportation hazards.

Code of Federal Regulations, 2013 CFR

2013-07-01

... transportation hazards. 109-40.113 Section 109-40.113 Public Contracts and Property Management Federal Property..., TRANSPORTATION, AND MOTOR VEHICLES 40-TRANSPORTATION AND TRAFFIC MANAGEMENT 40.1-General Provision § 109-40.113 Insurance against transportation hazards. The policy of the Government with respect to insurance of its...

27 CFR 70.113 - Penalty for failure to supply taxpayer identification number.

Code of Federal Regulations, 2010 CFR

2010-04-01

... supply taxpayer identification number. 70.113 Section 70.113 Alcohol, Tobacco Products and Firearms..., Additional Amounts, and Assessable Penalties § 70.113 Penalty for failure to supply taxpayer identification... notice and demand therefor. (b) Reasonable cause. If any person who is required by the regulations under...

46 CFR 169.113 - Right of appeal.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 7 2011-10-01 2011-10-01 false Right of appeal. 169.113 Section 169.113 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS General Provisions § 169.113 Right of appeal. Any person directly affected by a decision or action taken under this...

10 CFR 26.113 - Splitting the urine specimen.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 1 2013-01-01 2013-01-01 false Splitting the urine specimen. 26.113 Section 26.113 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Collecting Specimens for Testing § 26.113 Splitting the urine specimen. (a) Licensees and other entities may, but are not required to, use split...

10 CFR 26.113 - Splitting the urine specimen.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Splitting the urine specimen. 26.113 Section 26.113 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Collecting Specimens for Testing § 26.113 Splitting the urine specimen. (a) Licensees and other entities may, but are not required to, use split...

10 CFR 26.113 - Splitting the urine specimen.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 1 2014-01-01 2014-01-01 false Splitting the urine specimen. 26.113 Section 26.113 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Collecting Specimens for Testing § 26.113 Splitting the urine specimen. (a) Licensees and other entities may, but are not required to, use split...

45 CFR 690.113 - Suspension or termination of IRB approval of research.

Code of Federal Regulations, 2011 CFR

2011-10-01

... research. 690.113 Section 690.113 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION PROTECTION OF HUMAN SUBJECTS § 690.113 Suspension or termination of IRB approval of research. An IRB shall have authority to suspend or terminate approval of research that is not...

40 CFR 63.113 - Process vent provisions-reference control technology.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 10 2012-07-01 2012-07-01 false Process vent provisions-reference control technology. 63.113 Section 63.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... § 63.113 Process vent provisions—reference control technology. (a) The owner or operator of a Group 1...

40 CFR 63.113 - Process vent provisions-reference control technology.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 10 2013-07-01 2013-07-01 false Process vent provisions-reference control technology. 63.113 Section 63.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... § 63.113 Process vent provisions—reference control technology. (a) The owner or operator of a Group 1...

40 CFR 63.113 - Process vent provisions-reference control technology.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 9 2011-07-01 2011-07-01 false Process vent provisions-reference control technology. 63.113 Section 63.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... § 63.113 Process vent provisions—reference control technology. (a) The owner or operator of a Group 1...

40 CFR 63.113 - Process vent provisions-reference control technology.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 10 2014-07-01 2014-07-01 false Process vent provisions-reference control technology. 63.113 Section 63.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... § 63.113 Process vent provisions—reference control technology. (a) The owner or operator of a Group 1...

9 CFR 113.6 - Animal and Plant Health Inspection Service testing.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Animal and Plant Health Inspection Service testing. 113.6 Section 113.6 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION... STANDARD REQUIREMENTS Applicability § 113.6 Animal and Plant Health Inspection Service testing. A...

9 CFR 113.6 - Animal and Plant Health Inspection Service testing.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Animal and Plant Health Inspection Service testing. 113.6 Section 113.6 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION... STANDARD REQUIREMENTS Applicability § 113.6 Animal and Plant Health Inspection Service testing. A...

9 CFR 113.6 - Animal and Plant Health Inspection Service testing.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Animal and Plant Health Inspection Service testing. 113.6 Section 113.6 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION... STANDARD REQUIREMENTS Applicability § 113.6 Animal and Plant Health Inspection Service testing. A...

9 CFR 113.6 - Animal and Plant Health Inspection Service testing.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Animal and Plant Health Inspection Service testing. 113.6 Section 113.6 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION... STANDARD REQUIREMENTS Applicability § 113.6 Animal and Plant Health Inspection Service testing. A...

9 CFR 113.6 - Animal and Plant Health Inspection Service testing.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Animal and Plant Health Inspection Service testing. 113.6 Section 113.6 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION... STANDARD REQUIREMENTS Applicability § 113.6 Animal and Plant Health Inspection Service testing. A...

46 CFR 113.25-1 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-10-01

... GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM... §§ 113.25-25 and 113.25-30, applies to each manned vessel of over 100 gross tons, except barges, scows, and similar vessels. (b) Section 113.25-25 applies to each manned ocean and coastwise barge of over...

46 CFR 113.25-1 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-10-01

... GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM... §§ 113.25-25 and 113.25-30, applies to each manned vessel of over 100 gross tons, except barges, scows, and similar vessels. (b) Section 113.25-25 applies to each manned ocean and coastwise barge of over...

46 CFR 113.25-1 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-10-01

... GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM... §§ 113.25-25 and 113.25-30, applies to each manned vessel of over 100 gross tons, except barges, scows, and similar vessels. (b) Section 113.25-25 applies to each manned ocean and coastwise barge of over...

46 CFR 113.25-1 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-10-01

... GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM... §§ 113.25-25 and 113.25-30, applies to each manned vessel of over 100 gross tons, except barges, scows, and similar vessels. (b) Section 113.25-25 applies to each manned ocean and coastwise barge of over...

46 CFR 113.25-1 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-10-01

... GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM... §§ 113.25-25 and 113.25-30, applies to each manned vessel of over 100 gross tons, except barges, scows, and similar vessels. (b) Section 113.25-25 applies to each manned ocean and coastwise barge of over...

46 CFR 113.25-6 - Power supply.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Power supply. 113.25-6 Section 113.25-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-6 Power supply. The emergency power source...

46 CFR 113.25-6 - Power supply.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Power supply. 113.25-6 Section 113.25-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-6 Power supply. The emergency power source...

10 CFR 26.113 - Splitting the urine specimen.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Splitting the urine specimen. 26.113 Section 26.113 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Collecting Specimens for Testing § 26.113 Splitting the urine specimen. (a) Licensees and other entities may, but are not required to, use split...

10 CFR 26.113 - Splitting the urine specimen.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Splitting the urine specimen. 26.113 Section 26.113 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Collecting Specimens for Testing § 26.113 Splitting the urine specimen. (a) Licensees and other entities may, but are not required to, use split...

46 CFR 113.50-20 - Distribution of cable runs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Distribution of cable runs. 113.50-20 Section 113.50-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Public Address Systems § 113.50-20 Distribution of cable runs. (a) Each...

10 CFR 1304.113 - Privacy Act training.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Privacy Act training. 1304.113 Section 1304.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.113 Privacy Act training. (a) The Board... Board systems are informed of all requirements necessary to protect the privacy of individuals. The...

10 CFR 1304.113 - Privacy Act training.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Privacy Act training. 1304.113 Section 1304.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.113 Privacy Act training. (a) The Board... Board systems are informed of all requirements necessary to protect the privacy of individuals. The...

10 CFR 1304.113 - Privacy Act training.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Privacy Act training. 1304.113 Section 1304.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.113 Privacy Act training. (a) The Board... Board systems are informed of all requirements necessary to protect the privacy of individuals. The...

10 CFR 1304.113 - Privacy Act training.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Privacy Act training. 1304.113 Section 1304.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.113 Privacy Act training. (a) The Board... Board systems are informed of all requirements necessary to protect the privacy of individuals. The...

16 CFR 1028.113 - Suspension or termination of IRB approval of research.

Code of Federal Regulations, 2011 CFR

2011-01-01

... research. 1028.113 Section 1028.113 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL PROTECTION OF HUMAN SUBJECTS § 1028.113 Suspension or termination of IRB approval of research. An IRB shall have authority to suspend or terminate approval of research that is not being conducted in accordance...

10 CFR 1304.113 - Privacy Act training.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Privacy Act training. 1304.113 Section 1304.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.113 Privacy Act training. (a) The Board... Board systems are informed of all requirements necessary to protect the privacy of individuals. The...

45 CFR 81.113 - Ex parte communications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Ex parte communications. 81.113 Section 81.113 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PRACTICE AND PROCEDURE FOR HEARINGS UNDER PART 80 OF THIS TITLE Judicial Standards of Practice § 81.113 Ex parte communications. Only...

9 CFR 113.205 - Newcastle Disease Vaccine, Killed Virus.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Newcastle Disease Vaccine, Killed Virus. 113.205 Section 113.205 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... REQUIREMENTS Killed Virus Vaccines § 113.205 Newcastle Disease Vaccine, Killed Virus. Newcastle Disease Vaccine...

9 CFR 113.205 - Newcastle Disease Vaccine, Killed Virus.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Newcastle Disease Vaccine, Killed Virus. 113.205 Section 113.205 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... REQUIREMENTS Killed Virus Vaccines § 113.205 Newcastle Disease Vaccine, Killed Virus. Newcastle Disease Vaccine...

9 CFR 113.200 - General requirements for killed virus vaccines.

Code of Federal Regulations, 2014 CFR

2014-01-01

... vaccines. 113.200 Section 113.200 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... REQUIREMENTS Killed Virus Vaccines § 113.200 General requirements for killed virus vaccines. When prescribed in an applicable Standard Requirement or in the filed Outline of Production, a killed virus vaccine...

9 CFR 113.200 - General requirements for killed virus vaccines.

Code of Federal Regulations, 2013 CFR

2013-01-01

... vaccines. 113.200 Section 113.200 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... REQUIREMENTS Killed Virus Vaccines § 113.200 General requirements for killed virus vaccines. When prescribed in an applicable Standard Requirement or in the filed Outline of Production, a killed virus vaccine...

9 CFR 113.64 - General requirements for live bacterial vaccines.

Code of Federal Regulations, 2014 CFR

2014-01-01

... bacterial vaccines. 113.64 Section 113.64 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION... STANDARD REQUIREMENTS Live Bacterial Vaccines § 113.64 General requirements for live bacterial vaccines... bacterial vaccine shall meet the requirements in this section. (a) Purity test. Final container samples of...

9 CFR 113.313 - Measles Vaccine.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Measles Vaccine. 113.313 Section 113... Vaccines § 113.313 Measles Vaccine. Measles Vaccine shall be prepared from virus-bearing cell culture... for preparing the production seed virus for vaccine production. All serials of vaccine shall be...

9 CFR 113.64 - General requirements for live bacterial vaccines.

Code of Federal Regulations, 2012 CFR

2012-01-01

... bacterial vaccines. 113.64 Section 113.64 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION... STANDARD REQUIREMENTS Live Bacterial Vaccines § 113.64 General requirements for live bacterial vaccines... bacterial vaccine shall meet the requirements in this section. (a) Purity test. Final container samples of...

9 CFR 113.313 - Measles Vaccine.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Measles Vaccine. 113.313 Section 113... Vaccines § 113.313 Measles Vaccine. Measles Vaccine shall be prepared from virus-bearing cell culture... for preparing the production seed virus for vaccine production. All serials of vaccine shall be...

9 CFR 113.205 - Newcastle Disease Vaccine, Killed Virus.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Newcastle Disease Vaccine, Killed Virus. 113.205 Section 113.205 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... REQUIREMENTS Killed Virus Vaccines § 113.205 Newcastle Disease Vaccine, Killed Virus. Newcastle Disease Vaccine...

9 CFR 113.64 - General requirements for live bacterial vaccines.

Code of Federal Regulations, 2013 CFR

2013-01-01

... bacterial vaccines. 113.64 Section 113.64 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION... STANDARD REQUIREMENTS Live Bacterial Vaccines § 113.64 General requirements for live bacterial vaccines... bacterial vaccine shall meet the requirements in this section. (a) Purity test. Final container samples of...

9 CFR 113.205 - Newcastle Disease Vaccine, Killed Virus.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Newcastle Disease Vaccine, Killed Virus. 113.205 Section 113.205 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... REQUIREMENTS Killed Virus Vaccines § 113.205 Newcastle Disease Vaccine, Killed Virus. Newcastle Disease Vaccine...

9 CFR 113.200 - General requirements for killed virus vaccines.

Code of Federal Regulations, 2011 CFR

2011-01-01

... vaccines. 113.200 Section 113.200 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... REQUIREMENTS Killed Virus Vaccines § 113.200 General requirements for killed virus vaccines. When prescribed in an applicable Standard Requirement or in the filed Outline of Production, a killed virus vaccine...