46 CFR 107.283 - Certificate of Inspection: Conditions of validity.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Certificate of Inspection: Conditions of validity. 107.283 Section 107.283 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION Inspection and Certification § 107.283 Certificate of...

46 CFR 107.283 - Certificate of Inspection: Conditions of validity.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Certificate of Inspection: Conditions of validity. 107.283 Section 107.283 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION Inspection and Certification § 107.283 Certificate of...

7 CFR 283.16 - Consolidation of issues.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false Consolidation of issues. 283.16 Section 283.16... Claims of $50,000 or More § 283.16 Consolidation of issues. Similar issues involved in appeals by two or...) Disposition of consolidated issues. If the ALJ orders consolidation, the issues consolidated will be...

32 CFR 283.4 - Policy.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Policy. 283.4 Section 283.4 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS WAIVER OF DEBTS RESULTING FROM ERRONEOUS PAYMENTS OF PAY AND ALLOWANCES § 283.4 Policy. It is DoD policy that: (a...

7 CFR 283.12 - Discovery.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 4 2011-01-01 2011-01-01 false Discovery. 283.12 Section 283.12 Agriculture... of $50,000 or More § 283.12 Discovery. (a) Dispositions—(1) Motion for taking deposition. Only upon a... exist if the information sought appears reasonably calculated to lead to the discovery of admissible...

7 CFR 283.28 - Discovery.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 4 2014-01-01 2014-01-01 false Discovery. 283.28 Section 283.28 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... Appeals of QC Claims of Less Than $50,000 § 283.28 Discovery. Upon motion and as ordered by the ALJ...

7 CFR 283.28 - Discovery.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 4 2013-01-01 2013-01-01 false Discovery. 283.28 Section 283.28 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... Appeals of QC Claims of Less Than $50,000 § 283.28 Discovery. Upon motion and as ordered by the ALJ...

7 CFR 283.12 - Discovery.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 4 2012-01-01 2012-01-01 false Discovery. 283.12 Section 283.12 Agriculture... of $50,000 or More § 283.12 Discovery. (a) Dispositions—(1) Motion for taking deposition. Only upon a... exist if the information sought appears reasonably calculated to lead to the discovery of admissible...

7 CFR 283.12 - Discovery.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 4 2013-01-01 2013-01-01 false Discovery. 283.12 Section 283.12 Agriculture... of $50,000 or More § 283.12 Discovery. (a) Dispositions—(1) Motion for taking deposition. Only upon a... exist if the information sought appears reasonably calculated to lead to the discovery of admissible...

7 CFR 283.28 - Discovery.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 4 2011-01-01 2011-01-01 false Discovery. 283.28 Section 283.28 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... Appeals of QC Claims of Less Than $50,000 § 283.28 Discovery. Upon motion and as ordered by the ALJ...

7 CFR 283.12 - Discovery.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 4 2014-01-01 2014-01-01 false Discovery. 283.12 Section 283.12 Agriculture... of $50,000 or More § 283.12 Discovery. (a) Dispositions—(1) Motion for taking deposition. Only upon a... exist if the information sought appears reasonably calculated to lead to the discovery of admissible...

7 CFR 283.28 - Discovery.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 4 2012-01-01 2012-01-01 false Discovery. 283.28 Section 283.28 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... Appeals of QC Claims of Less Than $50,000 § 283.28 Discovery. Upon motion and as ordered by the ALJ...

7 CFR 283.28 - Discovery.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false Discovery. 283.28 Section 283.28 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... Appeals of QC Claims of Less Than $50,000 § 283.28 Discovery. Upon motion and as ordered by the ALJ...

7 CFR 283.23 - Procedural matters.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 4 2014-01-01 2014-01-01 false Procedural matters. 283.23 Section 283.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... of $50,000 or More § 283.23 Procedural matters. (a) Communications from Hearing Clerk. In order to...

7 CFR 283.23 - Procedural matters.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 4 2012-01-01 2012-01-01 false Procedural matters. 283.23 Section 283.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... of $50,000 or More § 283.23 Procedural matters. (a) Communications from Hearing Clerk. In order to...

7 CFR 283.23 - Procedural matters.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false Procedural matters. 283.23 Section 283.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... of $50,000 or More § 283.23 Procedural matters. (a) Communications from Hearing Clerk. In order to...

7 CFR 283.23 - Procedural matters.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 4 2011-01-01 2011-01-01 false Procedural matters. 283.23 Section 283.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... of $50,000 or More § 283.23 Procedural matters. (a) Communications from Hearing Clerk. In order to...

7 CFR 283.23 - Procedural matters.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 4 2013-01-01 2013-01-01 false Procedural matters. 283.23 Section 283.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... of $50,000 or More § 283.23 Procedural matters. (a) Communications from Hearing Clerk. In order to...

21 CFR 556.283 - Florfenicol.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Florfenicol. 556.283 Section 556.283 Food and... Residues of New Animal Drugs § 556.283 Florfenicol. (a) Acceptable daily intake (ADI). The ADI for total residues of florfenicol is 10 micrograms per kilogram of body weight per day. (b) Tolerances—(1) Cattle—(i...

21 CFR 556.283 - Florfenicol.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Florfenicol. 556.283 Section 556.283 Food and... Residues of New Animal Drugs § 556.283 Florfenicol. (a) Acceptable daily intake (ADI). The ADI for total residues of florfenicol is 10 micrograms per kilogram of body weight per day. (b) Tolerances—(1) Cattle—(i...

47 CFR 25.283 - End-of-life disposal.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false End-of-life disposal. 25.283 Section 25.283... Technical Operations § 25.283 End-of-life disposal. (a) Geostationary orbit space stations. Unless otherwise... satellite orbit under this part shall be relocated, at the end of its useful life, barring catastrophic...

47 CFR 25.283 - End-of-life disposal.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 2 2011-10-01 2011-10-01 false End-of-life disposal. 25.283 Section 25.283... Technical Operations § 25.283 End-of-life disposal. (a) Geostationary orbit space stations. Unless otherwise... satellite orbit under this part shall be relocated, at the end of its useful life, barring catastrophic...

45 CFR 283.1 - What does this part cover?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 2 2014-10-01 2012-10-01 true What does this part cover? 283.1 Section 283.1 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS...)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD DECREASE IN ILLEGITIMACY RATIO § 283.1 What does this...

45 CFR 283.1 - What does this part cover?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false What does this part cover? 283.1 Section 283.1 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS...)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD DECREASE IN ILLEGITIMACY RATIO § 283.1 What does this...

45 CFR 283.1 - What does this part cover?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false What does this part cover? 283.1 Section 283.1 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS...)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD DECREASE IN ILLEGITIMACY RATIO § 283.1 What does this...

45 CFR 283.1 - What does this part cover?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true What does this part cover? 283.1 Section 283.1 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS...)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD DECREASE IN ILLEGITIMACY RATIO § 283.1 What does this...

45 CFR 283.1 - What does this part cover?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 2 2012-10-01 2012-10-01 false What does this part cover? 283.1 Section 283.1 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS...)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD DECREASE IN ILLEGITIMACY RATIO § 283.1 What does this...

7 CFR 283.18 - Motions and requests.

Code of Federal Regulations, 2011 CFR

2011-01-01

... particular order, ruling, or action desired and the grounds therefor. (d) Response to motions and requests... 7 Agriculture 4 2011-01-01 2011-01-01 false Motions and requests. 283.18 Section 283.18... Claims of $50,000 or More § 283.18 Motions and requests. (a) Filing. All motions and requests shall be...

7 CFR 283.18 - Motions and requests.

Code of Federal Regulations, 2010 CFR

2010-01-01

... particular order, ruling, or action desired and the grounds therefor. (d) Response to motions and requests... 7 Agriculture 4 2010-01-01 2010-01-01 false Motions and requests. 283.18 Section 283.18... Claims of $50,000 or More § 283.18 Motions and requests. (a) Filing. All motions and requests shall be...

40 CFR 60.283 - Standard for total reduced sulfur (TRS).

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 6 2011-07-01 2011-07-01 false Standard for total reduced sulfur (TRS). 60.283 Section 60.283 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Pulp Mills § 60.283 Standard for total reduced sulfur (TRS). (a) On and after the date on which the...

40 CFR 60.283 - Standard for total reduced sulfur (TRS).

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 7 2014-07-01 2014-07-01 false Standard for total reduced sulfur (TRS). 60.283 Section 60.283 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Pulp Mills § 60.283 Standard for total reduced sulfur (TRS). (a) On and after the date on which the...

40 CFR 60.283 - Standard for total reduced sulfur (TRS).

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 7 2013-07-01 2013-07-01 false Standard for total reduced sulfur (TRS). 60.283 Section 60.283 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Pulp Mills § 60.283 Standard for total reduced sulfur (TRS). (a) On and after the date on which the...

40 CFR 60.283 - Standard for total reduced sulfur (TRS).

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 7 2012-07-01 2012-07-01 false Standard for total reduced sulfur (TRS). 60.283 Section 60.283 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Pulp Mills § 60.283 Standard for total reduced sulfur (TRS). (a) On and after the date on which the...

Prevalence and pattern of use of indigenous medicines in diabetic patients attending a tertiary care centre.

PubMed

Sethi, Ankur; Srivastava, Saurabh; Madhu, S V

2011-07-01

The aim of the study was to see the pattern of use of indigenous medicines in diabetic patients and to find out its correlation with various demographic variables in patients of type 2 diabetes. A sample of 113 patients with diabetes (type 1 and type 2) was interviewed using a structured questionnaire by trained medical personnel about the intake of indigenous medicines. Correlation of intake of indigenous medicines with various demographic variables was assessed using appropriate statistical tests. Male to female ratio in the present study was 1:3. Mean duration of diabetes was 5.2 +/- 2 years. It was found that majority of patients 101/113 (89.4%) attending diabetic clinic were using indigenous medicines in one form or the other. Most common drugs used were karela (78.8%), jamun (65.5%), methi (38.9%) and neem (28.3%). Majority were taking on advice from fellow diabetics (41.6%) and were not sure (39.8%) about the effect. No significant correlation was found with their intake and demographic variables as age, sex, per capita income, duration of diabtes, occupation, cultural background and antidiabetic medicine used. There is a high percentage of indigenous drug use in patients with diabetes which is often not reported. Treating physicians need to be alert to this possibility while managing diabetic patients in order to correctly interpret glycaemic control, hypoglycaemic episodes and other unexplained comorbidities that might arise in them.

Applied Mathematical Modules for Use in a Linear Algebra Service Course

DTIC Science & Technology

1990-05-01

H . (1977). Elements of ohysical chemistry. Reading, MA: Addison-Wesley. Rorres , C . & Anton , H . (1984). Applications...k t)r+ v𔃽 A142"+ c -- + C Vt +1 t+ C c tKc cos t 2= 113 123 313 32-3 51 2 V - cu-14sin r t) 232 _E _ VL3 h 3kx3 Cl t + c1 _3 t c + 3 =11-3 12 3 31 6... H " O H H H o 0 0 H H H H H H Ao, //o\\ H HH H

45 CFR 283.8 - What will be the amount of the bonus?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true What will be the amount of the bonus? 283.8 Section 283.8 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE... OF SECTION 403(A)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD DECREASE IN ILLEGITIMACY RATIO § 283...

45 CFR 283.8 - What will be the amount of the bonus?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 2 2014-10-01 2012-10-01 true What will be the amount of the bonus? 283.8 Section 283.8 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE... OF SECTION 403(A)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD DECREASE IN ILLEGITIMACY RATIO § 283...

7 CFR 283.5 - Motion to dismiss.

Code of Federal Regulations, 2011 CFR

2011-01-01

... motion to dismiss. The ALJ will rule on the motion to dismiss before any further action proceeds on the... 7 Agriculture 4 2011-01-01 2011-01-01 false Motion to dismiss. 283.5 Section 283.5 Agriculture... of $50,000 or More § 283.5 Motion to dismiss. (a) Filing of motion to dismiss. Prior to or at the...

7 CFR 283.5 - Motion to dismiss.

Code of Federal Regulations, 2010 CFR

2010-01-01

... motion to dismiss. The ALJ will rule on the motion to dismiss before any further action proceeds on the... 7 Agriculture 4 2010-01-01 2010-01-01 false Motion to dismiss. 283.5 Section 283.5 Agriculture... of $50,000 or More § 283.5 Motion to dismiss. (a) Filing of motion to dismiss. Prior to or at the...

40 CFR 60.283a - Standard for total reduced sulfur (TRS).

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 7 2014-07-01 2014-07-01 false Standard for total reduced sulfur (TRS). 60.283a Section 60.283a Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... 23, 2013 § 60.283a Standard for total reduced sulfur (TRS). (a) On and after the date on which the...

40 CFR 264.283 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

Code of Federal Regulations, 2011 CFR

2011-07-01

... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.283 Section 264.283 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land Treatment § 264.283 Special requirements...

40 CFR 264.283 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

Code of Federal Regulations, 2014 CFR

2014-07-01

... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.283 Section 264.283 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land Treatment § 264.283 Special requirements...

40 CFR 264.283 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

Code of Federal Regulations, 2013 CFR

2013-07-01

... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.283 Section 264.283 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land Treatment § 264.283 Special requirements...

40 CFR 264.283 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

Code of Federal Regulations, 2012 CFR

2012-07-01

... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.283 Section 264.283 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land Treatment § 264.283 Special requirements...

Prospects of A and Z identification experiments at LBNL

NASA Astrophysics Data System (ADS)

Gates, Jacklyn M.

2016-12-01

The identification of six new elements within the last 15 years and with proton numbers, Z = 113-118 has transformed the heavy element field. However, one key piece of information on these nuclei remains unmeasured: their proton and mass numbers, A. At Lawrence Berkeley National Laboratory, the heavy element group has undertaken a program to study these new elements to perform experiments aimed at measuring the Z and A.Here, an overview of recent experiments aimed towards identifying the Z of SHE, and the prospects for Z and A identification experiments at LBNL are presented.

Theoretical Predictions of Cross-Sections of the Super-Heavy Elements

NASA Astrophysics Data System (ADS)

Bouriquet, B.; Kosenko, G.; Abe, Y.

The evaluation of the residue cross-sections of reactionssynthesising superheavy elements has been achieved by the combination of the two-step model for fusion and the evaporation code (KEWPIE) for survival probability. The theoretical scheme of those calculations is presented, and some encouraging results are given, together with some difficulties. With this approach, the measured excitation functions of the 1n reactions producing elements with Z=108, 110, 111 and 112 are well reproduced. Thus, the model has been used to predict the cross-sections of the reactions leading to the formation of the elements with Z=113 and Z=114.

2015 Epidemic of Severe Streptococcus agalactiae Sequence Type 283 Infections in Singapore Associated With the Consumption of Raw Freshwater Fish: A Detailed Analysis of Clinical, Epidemiological, and Bacterial Sequencing Data.

PubMed

Kalimuddin, Shirin; Chen, Swaine L; Lim, Cindy T K; Koh, Tse Hsien; Tan, Thean Yen; Kam, Michelle; Wong, Christopher W; Mehershahi, Kurosh S; Chau, Man Ling; Ng, Lee Ching; Tang, Wen Ying; Badaruddin, Hishamuddin; Teo, Jeanette; Apisarnthanarak, Anucha; Suwantarat, Nuntra; Ip, Margaret; Holden, Matthew T G; Hsu, Li Yang; Barkham, Timothy

2017-05-15

Streptococcus agalactiae (group B Streptococcus [GBS]) has not been described as a foodborne pathogen. However, in 2015, a large outbreak of severe invasive sequence type (ST) 283 GBS infections in adults epidemiologically linked to the consumption of raw freshwater fish occurred in Singapore. We attempted to determine the scale of the outbreak, define the clinical spectrum of disease, and link the outbreak to contaminated fish. Time-series analysis was performed on microbiology laboratory data. Food handlers and fishmongers were screened for enteric carriage of GBS. A retrospective cohort study was conducted to assess differences in demographic and clinical characteristics of patients with invasive ST283 and non-ST283 infections. Whole-genome sequencing was performed on human and fish ST283 isolates from Singapore, Thailand, and Hong Kong. The outbreak was estimated to have started in late January 2015. Within the study cohort of 408 patients, ST283 accounted for 35.8% of cases. Patients with ST283 infection were younger and had fewer comorbidities but were more likely to develop meningoencephalitis, septic arthritis, and spinal infection. Of 82 food handlers and fishmongers screened, none carried ST283. Culture of 43 fish samples yielded 13 ST283-positive samples. Phylogenomic analysis of 161 ST283 isolates from humans and fish revealed they formed a tight clade distinguished by 93 single-nucleotide polymorphisms. ST283 is a zoonotic GBS clone associated with farmed freshwater fish, capable of causing severe disease in humans. It caused a large foodborne outbreak in Singapore and poses both a regional and potentially more widespread threat. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

August gamma Cepheids (523-AGC)

NASA Astrophysics Data System (ADS)

Roggemans, Paul

2018-02-01

Favorable weather conditions between 19 August and 5 September 2017 enabled the CAMS BeNeLux network to collect 3189 orbits. A radiant concentration was spotted which was identified as the August gamma Cepheids (523-AGC). An independent search on a selection from all available meteor orbit lists coming from the suspect radiant area and velocity range was made. This resulted in 283 similar orbits, radiating from R.A. 358.4° and Decl. +76.2° with a geocentric velocity of 43.7 km/s in a time lapse between 146° and 165° in solar longitude with best activity at 155.7°. The orbital elements match perfectly with previously published results. There is no indication for any periodicity in the shower displays from year to year. The AGC-meteors are remarkably rich in bright meteors and rather deficient in faint meteors. Being detected independently from orbital data collected by different video networks, confirmed by 283 orbits with a medium threshold D criterion DD < 0.08 and 125 orbits with a high threshold of DD < 0.04, this minor shower could be considered to be listed as an established meteor shower.

Molecular pathways underlying inhibitory effect of antimicrobial peptide Nal-P-113 on bacteria biofilms formation of Porphyromonas gingivalis W83 by DNA microarray.

PubMed

Wang, Hong-Yan; Lin, Li; Tan, Li-Si; Yu, Hui-Yuan; Cheng, Jya-Wei; Pan, Ya-Ping

2017-02-17

Wound-related infection remains a major challenge for health professionals. One disadvantage in conventional antibiotics is their inability to penetrate biofilms, the main protective strategy for bacteria to evade irradiation. Previously, we have shown that synthetic antimicrobial peptides could inhibit bacterial biofilms formation. In this study, we first delineated how Nal-P-113, a novel antimicrobial peptide, exerted its inhibitory effects on Porphyromonas gingivalis W83 biofilms formation at a low concentration. Secondly, we performed gene expression profiling and validated that Nal-P-113 at a low dose significantly down-regulated genes related to mobile and extrachromosomal element functions, transport and binding proteins in Porphyromonas gingivalis W83. These findings suggest that Nal-P-113 at low dose is sufficient to inhibit the formation of biofilms although Porphyromonas gingivalis W83 may maintain its survival in the oral cavity. The newly discovered molecular pathways may add the knowledge of developing a new strategy to target bacterial infections in combination with current first-line treatment in periodontitis.

49 CFR 192.283 - Plastic pipe: Qualifying joining procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

....283 Section 192.283 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Joining of...

25 CFR 1000.283 - If the Tribe/Consortium or Tribe's/Consortium's employee receives a summons and/or a complaint...

Code of Federal Regulations, 2010 CFR

2010-04-01

.../Consortium should immediately: (a) Inform the Assistant Solicitor, Procurement and Patents, Office of the...? 1000.283 Section 1000.283 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE...

25 CFR 1000.283 - If the Tribe/Consortium or Tribe's/Consortium's employee receives a summons and/or a complaint...

Code of Federal Regulations, 2013 CFR

2013-04-01

.../Consortium should immediately: (a) Inform the Assistant Solicitor, Procurement and Patents, Office of the...? 1000.283 Section 1000.283 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE...

25 CFR 1000.283 - If the Tribe/Consortium or Tribe's/Consortium's employee receives a summons and/or a complaint...

Code of Federal Regulations, 2012 CFR

2012-04-01

.../Consortium should immediately: (a) Inform the Assistant Solicitor, Procurement and Patents, Office of the...? 1000.283 Section 1000.283 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE...

25 CFR 1000.283 - If the Tribe/Consortium or Tribe's/Consortium's employee receives a summons and/or a complaint...

Code of Federal Regulations, 2011 CFR

2011-04-01

.../Consortium should immediately: (a) Inform the Assistant Solicitor, Procurement and Patents, Office of the...? 1000.283 Section 1000.283 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE...

25 CFR 1000.283 - If the Tribe/Consortium or Tribe's/Consortium's employee receives a summons and/or a complaint...

Code of Federal Regulations, 2014 CFR

2014-04-01

.../Consortium should immediately: (a) Inform the Assistant Solicitor, Procurement and Patents, Office of the...? 1000.283 Section 1000.283 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE...

STS-92 Mission Specialist Chiao drives the M-113

NASA Technical Reports Server (NTRS)

2000-01-01

With other crew members in the back, STS-92 Mission Specialist Leroy Chiao races the M-113 along the track through the scrub. Driving the M-113 is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

CMV-promoter driven codon-optimized expression alters the assembly type and morphology of a reconstituted HERV-K(HML-2).

PubMed

Hohn, Oliver; Hanke, Kirsten; Lausch, Veronika; Zimmermann, Anja; Mostafa, Saeed; Bannert, Norbert

2014-11-11

The HERV-K(HML-2) family contains the most recently integrated and best preserved endogenized proviral sequences in the human genome. All known elements have nevertheless been subjected to mutations or deletions that render expressed particles non-infectious. Moreover, these post-insertional mutations hamper the analysis of the general biological properties of this ancient virus family. The expression of consensus sequences and sequences of elements with reverted post-insertional mutations has therefore been very instrumental in overcoming this limitation. We investigated the particle morphology of a recently reconstituted HERV-K113 element termed oriHERV-K113 using thin-section electron microscopy (EM) and could demonstrate that strong overexpression by substitution of the 5'LTR for a CMV promoter and partial codon optimization altered the virus assembly type and morphology. This included a conversion from the regular C-type to an A-type morphology with a mass of cytoplasmic immature cores tethered to the cell membrane and the membranes of vesicles. Overexpression permitted the release and maturation of virions but reduced the envelope content. A weaker boost of virus expression by Staufen-1 was not sufficient to induce these morphological alterations.

CMV-Promoter Driven Codon-Optimized Expression Alters the Assembly Type and Morphology of a Reconstituted HERV-K(HML-2)

PubMed Central

Hohn, Oliver; Hanke, Kirsten; Lausch, Veronika; Zimmermann, Anja; Mostafa, Saeed; Bannert, Norbert

2014-01-01

The HERV-K(HML-2) family contains the most recently integrated and best preserved endogenized proviral sequences in the human genome. All known elements have nevertheless been subjected to mutations or deletions that render expressed particles non-infectious. Moreover, these post-insertional mutations hamper the analysis of the general biological properties of this ancient virus family. The expression of consensus sequences and sequences of elements with reverted post-insertional mutations has therefore been very instrumental in overcoming this limitation. We investigated the particle morphology of a recently reconstituted HERV-K113 element termed oriHERV-K113 using thin-section electron microscopy (EM) and could demonstrate that strong overexpression by substitution of the 5'LTR for a CMV promoter and partial codon optimization altered the virus assembly type and morphology. This included a conversion from the regular C-type to an A-type morphology with a mass of cytoplasmic immature cores tethered to the cell membrane and the membranes of vesicles. Overexpression permitted the release and maturation of virions but reduced the envelope content. A weaker boost of virus expression by Staufen-1 was not sufficient to induce these morphological alterations. PMID:25393897

Prediction of near-term breast cancer risk using local region-based bilateral asymmetry features in mammography

NASA Astrophysics Data System (ADS)

Li, Yane; Fan, Ming; Li, Lihua; Zheng, Bin

2017-03-01

This study proposed a near-term breast cancer risk assessment model based on local region bilateral asymmetry features in Mammography. The database includes 566 cases who underwent at least two sequential FFDM examinations. The `prior' examination in the two series all interpreted as negative (not recalled). In the "current" examination, 283 women were diagnosed cancers and 283 remained negative. Age of cancers and negative cases completely matched. These cases were divided into three subgroups according to age: 152 cases among the 37-49 age-bracket, 220 cases in the age-bracket 50- 60, and 194 cases with the 61-86 age-bracket. For each image, two local regions including strip-based regions and difference-of-Gaussian basic element regions were segmented. After that, structural variation features among pixel values and structural similarity features were computed for strip regions. Meanwhile, positional features were extracted for basic element regions. The absolute subtraction value was computed between each feature of the left and right local-regions. Next, a multi-layer perception classifier was implemented to assess performance of features for prediction. Features were then selected according stepwise regression analysis. The AUC achieved 0.72, 0.75 and 0.71 for these 3 age-based subgroups, respectively. The maximum adjustable odds ratios were 12.4, 20.56 and 4.91 for these three groups, respectively. This study demonstrate that the local region-based bilateral asymmetry features extracted from CC-view mammography could provide useful information to predict near-term breast cancer risk.

37 CFR 2.83 - Conflicting marks.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Trademarks until the published or issued application is registered or abandoned. [37 FR 2880, Feb. 9, 1972... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Conflicting marks. 2.83 Section 2.83 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF...

32 CFR 283.2 - Applicability and scope.

Code of Federal Regulations, 2013 CFR

2013-07-01

... of Homeland Security, and the Commissioned Corps of the Public Health Service (PHS) and the National... 32 National Defense 2 2013-07-01 2013-07-01 false Applicability and scope. 283.2 Section 283.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED...

32 CFR 283.2 - Applicability and scope.

Code of Federal Regulations, 2014 CFR

2014-07-01

... of Homeland Security, and the Commissioned Corps of the Public Health Service (PHS) and the National... 32 National Defense 2 2014-07-01 2014-07-01 false Applicability and scope. 283.2 Section 283.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED...

40 CFR 52.283 - Interstate Transport.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Interstate Transport. 52.283 Section 52...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.283 Interstate Transport. Link to an... Resources Board submitted the “Interstate Transport State Implementation Plan (SIP) for the 1997 8-hour...

14 CFR 121.283 - Induction system ice prevention.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Induction system ice prevention. 121.283 Section 121.283 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... Induction system ice prevention. A means for preventing the malfunctioning of each engine due to ice...

14 CFR 121.283 - Induction system ice prevention.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Induction system ice prevention. 121.283 Section 121.283 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... Induction system ice prevention. A means for preventing the malfunctioning of each engine due to ice...

14 CFR 121.283 - Induction system ice prevention.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Induction system ice prevention. 121.283 Section 121.283 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... Induction system ice prevention. A means for preventing the malfunctioning of each engine due to ice...

14 CFR 121.283 - Induction system ice prevention.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Induction system ice prevention. 121.283 Section 121.283 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... Induction system ice prevention. A means for preventing the malfunctioning of each engine due to ice...

14 CFR 121.283 - Induction system ice prevention.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Induction system ice prevention. 121.283 Section 121.283 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... Induction system ice prevention. A means for preventing the malfunctioning of each engine due to ice...

5 CFR 532.283 - Special wage schedules for nonappropriated fund tipped employees classified as waiter/waitress.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Special wage schedules for nonappropriated fund tipped employees classified as waiter/waitress. 532.283 Section 532.283 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PREVAILING RATE SYSTEMS Prevailing Rate...

7 CFR 283.21 - Ex parte communications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... of all such oral communications; and (3) Copies of all written responses, and memoranda stating the substance of all oral responses thereto. (4) Upon receipt of a communication knowingly made or knowingly... 7 Agriculture 4 2010-01-01 2010-01-01 false Ex parte communications. 283.21 Section 283.21...

7 CFR 283.7 - Procedures upon failure to file an answer.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false Procedures upon failure to file an answer. 283.7 Section 283.7 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION... filed, the State agency's motion shall be denied with supporting reasons. If meritorious objections are...

7 CFR 283.31 - Review of the record.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false Review of the record. 283.31 Section 283.31 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF... review the cross motions for summary judgment, briefs, reply briefs and supporting materials submitted by...

7 CFR 283.32 - ALJ's initial decision.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false ALJ's initial decision. 283.32 Section 283.32 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF... the State agency submits the notice of appeal and evidence in support of the appeal. The ALJ may...

7 CFR 283.10 - Consent decision.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false Consent decision. 283.10 Section 283.10 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... of the document. Such decision shall be final and shall take effect 30 days after the date of the...

7 CFR 283.31 - Review of the record.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 4 2011-01-01 2011-01-01 false Review of the record. 283.31 Section 283.31 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF... addressed and shall specify the date(s) by which such information or briefing must be provided. Upon receipt...

7 CFR 283.10 - Consent decision.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 4 2011-01-01 2011-01-01 false Consent decision. 283.10 Section 283.10 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... of the document. Such decision shall be final and shall take effect 30 days after the date of the...

28 CFR 2.83 - Release planning.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Release planning. 2.83 Section 2.83... Release planning. (a) All grants of parole shall be conditioned on the development of a suitable release... parole date for purposes of release planning for up to 120 days without a hearing. If efforts to...

Strategic Forum. Number 283, December 2013. Next Steps in Syria

DTIC Science & Technology

2013-12-01

www.ndu.edu/ inss SF No. 283 1 Nearly 3 years since the start of the Syrian civil war, no clear winner is in sight. Assassinations and defections of...ABSTRACT unclassified c. THIS PAGE unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 2 SF No. 283 www.ndu.edu/ inss ◆◆ U.S...in power and Russia and Iran quickly assert their influence through them to restrict www.ndu.edu/ inss SF No. 283 3 the scope of change. They

Mineral composition of durum wheat grain and pasta under increasing atmospheric CO2 concentrations.

PubMed

Beleggia, Romina; Fragasso, Mariagiovanna; Miglietta, Franco; Cattivelli, Luigi; Menga, Valeria; Nigro, Franca; Pecchioni, Nicola; Fares, Clara

2018-03-01

The concentrations of 10 minerals were investigated in the grain of 12 durum wheat genotypes grown under free air CO 2 enrichment conditions, and in four of their derived pasta samples, using inductively coupled plasma mass spectrometry. Compared to ambient CO 2 (400ppm; AMB), under elevated CO 2 (570ppm; ELE), the micro-element and macro-element contents showed strong and significant decreases in the grain: Mn, -28.3%; Fe, -26.7%; Zn, -21.9%; Mg, -22.7%; Mo, -40.4%; K, -22.4%; and Ca, -19.5%. These variations defined the 12 genotypes as sensitive or non-sensitive to ELE. The pasta samples under AMB and ELE showed decreased mineral contents compared to the grain. Nevertheless, the contributions of the pasta to the recommended daily allowances remained relevant, also for the micro-elements under ELE conditions (range, from 18% of the recommended daily allowance for Zn, to 70% for Mn and Mo). Copyright © 2017 Elsevier Ltd. All rights reserved.

Direct Measurement of Trace Elemental Mercury in Hydrocarbon Matrices by Gas Chromatography with Ultraviolet Photometric Detection.

PubMed

Gras, Ronda; Luong, Jim; Shellie, Robert A

2015-11-17

We introduce a technique for the direct measurement of elemental mercury in light hydrocarbons such as natural gas. We determined elemental mercury at the parts-per-trillion level with high precision [<3% RSD (n = 20 manual injection)] using gas chromatography with ultraviolet photometric detection (GC-UV) at 254 nm. Our approach requires a small sample volume (1 mL) and does not rely on any form of sample preconcentration. The GC-UV separation employs an inert divinylbenzene porous layer open tubular column set to separate mercury from other components in the sample matrix. We incorporated a 10-port gas-sampling valve in the GC-UV system, which enables automated sampling, as well as back flushing capability to enhance system cleanliness and sample throughput. Total analysis time is <2 min, and the procedure is linear over a range of 2-83 μg/m(3) [correlation coefficient of R(2) = 0.998] with a measured recovery of >98% over this range.

p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and senescence in response to DNA damage.

PubMed

Gong, Lu; Gong, Hongjian; Pan, Xiao; Chang, Changqing; Ou, Zhao; Ye, Shengfan; Yin, Le; Yang, Lina; Tao, Ting; Zhang, Zhenhai; Liu, Cong; Lane, David P; Peng, Jinrong; Chen, Jun

2015-03-01

The inhibitory role of p53 in DNA double-strand break (DSB) repair seems contradictory to its tumor-suppressing property. The p53 isoform Δ113p53/Δ133p53 is a p53 target gene that antagonizes p53 apoptotic activity. However, information on its functions in DNA damage repair is lacking. Here we report that Δ113p53 expression is strongly induced by γ-irradiation, but not by UV-irradiation or heat shock treatment. Strikingly, Δ113p53 promotes DNA DSB repair pathways, including homologous recombination, non-homologous end joining and single-strand annealing. To study the biological significance of Δ113p53 in promoting DNA DSB repair, we generated a zebrafish Δ113p53(M/M) mutant via the transcription activator-like effector nuclease technique and found that the mutant is more sensitive to γ-irradiation. The human ortholog, Δ133p53, is also only induced by γ-irradiation and functions to promote DNA DSB repair. Δ133p53-knockdown cells were arrested at the G2 phase at the later stage in response to γ-irradiation due to a high level of unrepaired DNA DSBs, which finally led to cell senescence. Furthermore, Δ113p53/Δ133p53 promotes DNA DSB repair via upregulating the transcription of repair genes rad51, lig4 and rad52 by binding to a novel type of p53-responsive element in their promoters. Our results demonstrate that Δ113p53/Δ133p53 is an evolutionally conserved pro-survival factor for DNA damage stress by preventing apoptosis and promoting DNA DSB repair to inhibit cell senescence. Our data also suggest that the induction of Δ133p53 expression in normal cells or tissues provides an important tolerance marker for cancer patients to radiotherapy.

14 CFR 125.283 - Second-in-command qualifications.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Second-in-command qualifications. 125.283... Requirements § 125.283 Second-in-command qualifications. No certificate holder may use any person, nor may any person serve, as second in command of an airplane unless that person— (a) Holds at least a commercial...

14 CFR 125.283 - Second-in-command qualifications.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Second-in-command qualifications. 125.283... Requirements § 125.283 Second-in-command qualifications. No certificate holder may use any person, nor may any person serve, as second in command of an airplane unless that person— (a) Holds at least a commercial...

14 CFR 125.283 - Second-in-command qualifications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Second-in-command qualifications. 125.283... Requirements § 125.283 Second-in-command qualifications. No certificate holder may use any person, nor may any person serve, as second in command of an airplane unless that person— (a) Holds at least a commercial...

14 CFR 125.283 - Second-in-command qualifications.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Second-in-command qualifications. 125.283... Requirements § 125.283 Second-in-command qualifications. No certificate holder may use any person, nor may any person serve, as second in command of an airplane unless that person— (a) Holds at least a commercial...

14 CFR 125.283 - Second-in-command qualifications.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Second-in-command qualifications. 125.283... Requirements § 125.283 Second-in-command qualifications. No certificate holder may use any person, nor may any person serve, as second in command of an airplane unless that person— (a) Holds at least a commercial...

7 CFR 283.27 - Procedures upon failure to file an answer.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false Procedures upon failure to file an answer. 283.27 Section 283.27 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION... objections have been filed, the State agency's motion shall be denied with supporting reasons. If meritorious...

49 CFR 40.283 - How does a certification organization obtain recognition for its members as SAPs?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 1 2012-10-01 2012-10-01 false How does a certification organization obtain recognition for its members as SAPs? 40.283 Section 40.283 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Substance Abuse...

49 CFR 40.283 - How does a certification organization obtain recognition for its members as SAPs?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 1 2013-10-01 2013-10-01 false How does a certification organization obtain recognition for its members as SAPs? 40.283 Section 40.283 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Substance Abuse...

49 CFR 40.283 - How does a certification organization obtain recognition for its members as SAPs?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 1 2011-10-01 2011-10-01 false How does a certification organization obtain recognition for its members as SAPs? 40.283 Section 40.283 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Substance Abuse...

49 CFR 40.283 - How does a certification organization obtain recognition for its members as SAPs?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 1 2014-10-01 2014-10-01 false How does a certification organization obtain recognition for its members as SAPs? 40.283 Section 40.283 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Substance Abuse...

49 CFR 40.283 - How does a certification organization obtain recognition for its members as SAPs?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false How does a certification organization obtain recognition for its members as SAPs? 40.283 Section 40.283 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Substance Abuse...

36 CFR 28.3 - Boundaries: The Community Development District; The Dune District; The Seashore District.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Boundaries: The Community Development District; The Dune District; The Seashore District. 28.3 Section 28.3 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR FIRE ISLAND NATIONAL SEASHORE: ZONING STANDARDS...

20 CFR 404.283 - Recomputation under method other than that used to find your primary insurance amount.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Recomputation under method other than that used to find your primary insurance amount. 404.283 Section 404.283 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Computing Primary Insurance Amounts...

7 CFR 283.1 - Meaning of words.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false Meaning of words. 283.1 Section 283.1 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... Meaning of words. As used in this part, words in the singular form shall be deemed to import the plural...

36 CFR 28.3 - Boundaries: The Community Development District; The Dune District; The Seashore District.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Boundaries: The Community Development District; The Dune District; The Seashore District. 28.3 Section 28.3 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR FIRE ISLAND NATIONAL SEASHORE: ZONING STANDARDS...

Appearance of drug resistance-associated mutations in human immunodeficiency virus type 1 protease and reverse transcriptase derived from drug-treated Indonesian patients.

PubMed

Khairunisa, Siti Qamariyah; Kotaki, Tomohiro; Witaningrum, Adiana Mutamsari; Yunifiar M, Muhammad Qushai; Sukartiningrum, Septhia Dwi; Nasronudin; Kameoka, Masanori

2015-02-01

Although HIV-1 drug resistance is a major obstacle in Indonesia, information on drug resistance is limited. In this study, the viral subtype and appearance of drug resistance mutations in the HIV-1 protease (PR) and reverse transcriptase (RT) genes were determined among drug-treated, HIV-1-infected patients in Surabaya. HIV-1 patients who received antiretroviral therapy (ART) more than 2 years were randomly recruited regardless of the viral load or ART failure. Fifty-eight HIV-1 PR genes and 53 RT genes were sequenced. CRF01_AE viruses were identified as the predominant strain. Major drug resistance mutations were not detected in the PR genes. In contrast, 37.7% (20/53) of the participants had one or more major drug resistance mutations in the RT genes, predominantly M184V (28.3%), K103N (11.3%), and thymidine analogue mutations (TAMs) (20.8%). The high prevalence of drug resistance mutations in RT genes indicated the necessity of monitoring the effectiveness of ART in Indonesia.

Registry-based Diabetes Risk Detection Schema for the Systematic Identification of Patients at Risk for Diabetes in West Virginia Primary Care Centers

PubMed Central

Baus, Adam; Wood, Gina; Pollard, Cecil; Summerfield, Belinda; White, Emma

2013-01-01

Approximately 466,000 West Virginians, or about 25 percent of the state population, have prediabetes and are at high risk for developing type 2 diabetes. Appropriate lifestyle intervention can prevent or delay the onset of type 2 diabetes if individuals at risk are identified and treated early. The West Virginia Diabetes Prevention and Control Program and the West Virginia University Office of Health Services Research are developing a systematic approach to diabetes prevention within primary care. This study aims to demonstrate the viability of patient registry software for the analysis of disparate electronic health record (EHR) data sets and standardized identification of at-risk patients for early detection and intervention. Preliminary analysis revealed that of 94,283 patients without a documented diagnosis of diabetes or prediabetes, 10,673 (11.3 percent) meet one or more of the risk criteria. This study indicates that EHR data can be repurposed into an actionable registry for prevention. This model supports meaningful use of EHRs, the Patient-Centered Medical Home program, and improved care through enhanced data management. PMID:24159274

Simulators for Mariner Training and Licensing: Guidelines for Deck Officer Training Systems.

DTIC Science & Technology

1982-12-01

Information regarding the three major elements of the training system - the simu- lator design , the training program structure, and the instructor...1.1.2 Empirical Research/ Experimentation Phase ........................................ 1 1.1.3 Major Product...3 3.2 Simulator Design (Critical Characteristics) ......................................... 13 3.2.1 Visual Scee

32 CFR 11.3 - General.

Code of Federal Regulations, 2010 CFR

2010-07-01

... crimes and elements derive from the law of armed conflict, a body of law that is sometimes referred to as... with that body of law, are triable by military commission. Because this document is declarative of... of other laws. No conclusion regarding the applicability or persuasive authority of other bodies of...

32 CFR 11.3 - General.

Code of Federal Regulations, 2014 CFR

2014-07-01

... crimes and elements derive from the law of armed conflict, a body of law that is sometimes referred to as... with that body of law, are triable by military commission. Because this document is declarative of... of other laws. No conclusion regarding the applicability or persuasive authority of other bodies of...

32 CFR 11.3 - General.

Code of Federal Regulations, 2013 CFR

2013-07-01

... crimes and elements derive from the law of armed conflict, a body of law that is sometimes referred to as... with that body of law, are triable by military commission. Because this document is declarative of... of other laws. No conclusion regarding the applicability or persuasive authority of other bodies of...

32 CFR 11.3 - General.

Code of Federal Regulations, 2011 CFR

2011-07-01

... crimes and elements derive from the law of armed conflict, a body of law that is sometimes referred to as... with that body of law, are triable by military commission. Because this document is declarative of... of other laws. No conclusion regarding the applicability or persuasive authority of other bodies of...

32 CFR 11.3 - General.

Code of Federal Regulations, 2012 CFR

2012-07-01

... crimes and elements derive from the law of armed conflict, a body of law that is sometimes referred to as... with that body of law, are triable by military commission. Because this document is declarative of... of other laws. No conclusion regarding the applicability or persuasive authority of other bodies of...

45 CFR 283.3 - What steps will we follow to award the bonus?

Code of Federal Regulations, 2010 CFR

2010-10-01

... will consider them for the bonus if they submit data on abortions as stated in § 283.6; and (5) Identify which of the potentially eligible States that submitted the required data on abortions have experienced decreases in their rates of abortion relative to 1995, as described in § 283.7. These States will...

45 CFR 283.8 - What will be the amount of the bonus?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false What will be the amount of the bonus? 283.8 Section 283.8 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE... IMPLEMENTATION OF SECTION 403(A)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD DECREASE IN ILLEGITIMACY RATIO...

45 CFR 283.8 - What will be the amount of the bonus?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 2 2012-10-01 2012-10-01 false What will be the amount of the bonus? 283.8 Section 283.8 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE... IMPLEMENTATION OF SECTION 403(A)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD DECREASE IN ILLEGITIMACY RATIO...

45 CFR 283.8 - What will be the amount of the bonus?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false What will be the amount of the bonus? 283.8 Section 283.8 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE... IMPLEMENTATION OF SECTION 403(A)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD DECREASE IN ILLEGITIMACY RATIO...

45 CFR 283.3 - What steps will we follow to award the bonus?

Code of Federal Regulations, 2012 CFR

2012-10-01

... will consider them for the bonus if they submit data on abortions as stated in § 283.6; and (5) Identify which of the potentially eligible States that submitted the required data on abortions have experienced decreases in their rates of abortion relative to 1995, as described in § 283.7. These States will...

45 CFR 283.3 - What steps will we follow to award the bonus?

Code of Federal Regulations, 2013 CFR

2013-10-01

... will consider them for the bonus if they submit data on abortions as stated in § 283.6; and (5) Identify which of the potentially eligible States that submitted the required data on abortions have experienced decreases in their rates of abortion relative to 1995, as described in § 283.7. These States will...

45 CFR 283.3 - What steps will we follow to award the bonus?

Code of Federal Regulations, 2011 CFR

2011-10-01

... will consider them for the bonus if they submit data on abortions as stated in § 283.6; and (5) Identify which of the potentially eligible States that submitted the required data on abortions have experienced decreases in their rates of abortion relative to 1995, as described in § 283.7. These States will...

45 CFR 283.3 - What steps will we follow to award the bonus?

Code of Federal Regulations, 2014 CFR

2014-10-01

... will consider them for the bonus if they submit data on abortions as stated in § 283.6; and (5) Identify which of the potentially eligible States that submitted the required data on abortions have experienced decreases in their rates of abortion relative to 1995, as described in § 283.7. These States will...

75 FR 15627 - Airworthiness Directives; Turbomeca Astazou XIV B and XIV H Turboshaft Engines

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-30

... the riveting detail. SN 283 72 0805 provides instructions for re-boring the holes at overhaul or... 173 by changing only the riveting detail. SB 283 72 0805 provides instructions for re-boring the holes... 173 by changing only the riveting detail. SN 283 72 0805 provides instructions for re-boring the holes...

K2-113: a dense hot-Jupiter transiting a solar analogue

NASA Astrophysics Data System (ADS)

Espinoza, Néstor; Rabus, Markus; Brahm, Rafael; Jones, Matías; Jordán, Andrés; Rojas, Felipe; Drass, Holger; Vučković, Maja; Hartman, Joel D.; Jenkins, James S.; Cortés, Cristián

2017-11-01

We present the discovery of K2-113, a dense hot-Jupiter discovered using photometry from Campaign 8 of the Kepler-2 (K2) mission and high-resolution spectroscopic follow-up obtained with the FEROS spectrograph. The planet orbits a V = 13.68 solar analogue in a P=5.817 60^{+0.000 03}_{-0.000 03} d orbit, and has a radius of 0.93^{+0.10}_{-0.07}R_J and a mass of 1.29^{+0.13}_{-0.14}M_J. With a density of 1.97^{+0.60}_{-0.53} g cm-3, the planet is among the densest systems known having masses below 2 MJ and T_eq > 1000, and is just above the temperature limit at which inflation mechanisms are believed to start being important. Based on its mass and radius, we estimate that K2-113 should have a heavy element content of the order of ˜110 M⊕ or greater.

Exploring quinolone resistance-determining region in Neisseria gonorrhoeae isolates from across India.

PubMed

Sood, Seema; Agarwal, Madhav; Bala, Manju; Mahajan, Neeraj; Singh, Rajendra; Kapil, Arti; Sreenivas, Vishnubhatla; Ram, R J; Kar, Hemanta Kumar; Sharma, Vinod Kumar

2017-07-01

Antimicrobial resistance in Neisseria gonorrhoeae, the causative agent of gonorrhoea, is a subject of worldwide attention. The present study was undertaken to examine the rates of ciprofloxacin resistance, to correlate mutations in gyrA and parC genes with the level of resistance and to look for a variation in mutation pattern, if any, in isolates from across the country. A total of 113 isolates of N. gonorrhoeae collected from sexually transmitted infection patients in six centres during November 2010 to October 2013 were investigated. Minimum inhibitory concentration (MIC) determination was done by E-test and results interpreted as per Calibrated Dichotomous Sensitivity criteria. DNA sequence analysis of gyrA and parC genes was done. Of the 113 isolates, only three (2.6%) were susceptible whereas eight (7.07%) were less susceptible, 32 [28.3%, 95% confidence interval (CI): 20.4-37.6%] resistant (MIC 1-3 μg/ml) and 70 (61.9%, 95% CI: 52.2-70.7%) exhibited high-level resistance (HLR) (MIC ≥4 μg/ml) to ciprofloxacin. A S91F substitution in gyrA gene was demonstrated in all ciprofloxacin non-susceptible isolates. All resistant and HLR isolates had a double mutation in gyrA gene. However, only 5.7 per cent of HLR isolates showed double mutations in parC gene. One isolate (MIC 32 μg/ml) had a previously undescribed G85D substitution in the parC gene. A S91F substitution in gyrA gene was seen in all non-susceptible isolates of N. gonorrhoeae. It may be used as a marker for ciprofloxacin resistance for molecular surveillance approaches to complement the culture-based methods.

45 CFR 283.5 - How will we use these birth data to determine bonus eligibility?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true How will we use these birth data to determine bonus eligibility? 283.5 Section 283.5 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY... SERVICES IMPLEMENTATION OF SECTION 403(A)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD DECREASE IN...

45 CFR 283.5 - How will we use these birth data to determine bonus eligibility?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 2 2014-10-01 2012-10-01 true How will we use these birth data to determine bonus eligibility? 283.5 Section 283.5 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY... SERVICES IMPLEMENTATION OF SECTION 403(A)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD DECREASE IN...

45 CFR 283.5 - How will we use these birth data to determine bonus eligibility?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false How will we use these birth data to determine bonus eligibility? 283.5 Section 283.5 Public Welfare Regulations Relating to Public Welfare OFFICE OF... AND HUMAN SERVICES IMPLEMENTATION OF SECTION 403(A)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD...

45 CFR 283.5 - How will we use these birth data to determine bonus eligibility?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 2 2012-10-01 2012-10-01 false How will we use these birth data to determine bonus eligibility? 283.5 Section 283.5 Public Welfare Regulations Relating to Public Welfare OFFICE OF... AND HUMAN SERVICES IMPLEMENTATION OF SECTION 403(A)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD...

45 CFR 283.5 - How will we use these birth data to determine bonus eligibility?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false How will we use these birth data to determine bonus eligibility? 283.5 Section 283.5 Public Welfare Regulations Relating to Public Welfare OFFICE OF... AND HUMAN SERVICES IMPLEMENTATION OF SECTION 403(A)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD...

Application of high-resolution continuum source flame atomic absorption spectrometry to reveal, evaluate and overcome certain spectral effects in Pb determination of unleaded gasoline

NASA Astrophysics Data System (ADS)

Kowalewska, Zofia; Laskowska, Hanna; Gzylewski, Michał

2017-06-01

High-resolution continuum source and line source flame atomic absorption spectrometry (HR-CS FAAS and LS FAAS, respectively) were applied for Pb determination in unleaded aviation or automotive gasoline that was dissolved in methyl-isobutyl ketone. When using HR-CS FAAS, a structured background (BG) was registered in the vicinity of both the 217.001 nm and 283.306 nm Pb lines. In the first case, the BG, which could be attributed to absorption by the OH molecule, directly overlaps with the 217 nm line, but it is of relatively low intensity. For the 283 nm line, the structured BG occurs due to uncompensated absorption by OH molecules present in the flame. BG lines of relatively high intensity are situated at a large distance from the 283 nm line, which enables accurate analysis, not only when using simple variants of HR-CS FAAS but also for LS FAAS with a bandpass of 0.1 nm. The lines of the structured spectrum at 283 nm can have ;absorption; (maxima) or ;emission; (minima) character. The intensity of the OH spectra can significantly depend on the flame character and composition of the investigated organic solution. The best detection limit for the analytical procedure, which was 0.01 mg L- 1 for Pb in the investigated solution, could be achieved using HR-CS FAAS with the 283 nm Pb line, 5 pixels for the analyte line measurement and iterative background correction (IBC). In this case, least squares background correction (LSBC) is not recommended. However, LSBC (available as the ;permanent structures; option) would be recommended when using the 217 nm Pb line. In LS FAAS, an additional phenomenon related to the nature of the organic matrix (for example, isooctane or toluene) can play an important role. The effect is of continuous character and probably due to the simultaneous efficient correction of the continuous background (IBC) it is not observed in HR-CS FAAS. The fact that the effect does not depend on the flame character indicates that it is not radiation scattering. For LS FAAS, the determination of Pb using the 283 nm line, a 0.1 nm bandpass and a fuel lean flame is strongly recommended. The analysis of certified reference materials, recovery studies and the analysis of real samples with low Pb content supported the satisfactory accuracy of Pb determination in automotive or aviation gasoline when the recommended analytical variants are applied. The studies in this work shed new light on spectral phenomena in air-acetylene flames. The structured background due to absorption by the OH molecules must be taken into account during Pb determination in other materials as well as in some other elemental determinations, especially at low absorbance levels. The usefulness of HR-CS FAAS for revealing and investigating a structured background was demonstrated. HR-CS FAAS does not reveal fully corrected spectral effects with a continuous character, which can be found in LS FAAS.

Discordant expression and variable numbers of neighboring GGA- and GAA-rich triplet repeats in the 3' untranslated regions of two groups of messenger RNAs encoded by the rat polymeric immunoglobulin receptor gene.

PubMed Central

Koch, K S; Gleiberman, A S; Aoki, T; Leffert, H L; Feren, A; Jones, A L; Fodor, E J

1995-01-01

An unusual S1-nuclease sensitive microsatellite (STMS) has been found in the single copy, rat polymeric immunoglobulin receptor gene (PIGR) terminal exon. In Fisher rats, elements within or beyond the STMS are expressed variably in the 3' untranslated regions (3'UTRs) of two 'Groups' of PIGR-encoded hepatic mRNAs (pIg-R) during liver regeneration. STMS elements include neighboring constant regions (a 60-bp d[GA]-rich tract with a chi-like octamer, followed by 15 tandem d[GGA] repeats) that merge directly with 36 or 39 tandem d[GAA] repeats (Fisher or Wistar strains, respectively) interrupted by d[AA] between their 5th-6th repeat units. The Wistar STMS is flanked upstream by two regions of nearly contiguous d[CA] or d[CT] repeats in the 3' end of intron 8; and downstream, by a 283 bp 'unit' containing several inversions at its 5' end, and two polyadenylation signals at its 3' end. The 283 nt unit is expressed in Group 1 pIg-R mRNAs; but it is absent in the Group 2 family so that their GAA repeats merge with their poly A tails. In contrast to genomic sequence, GGA triplet repeats are amplified (n > or = 24-26), whereas GAA triplet repeats are truncated variably (n < or = 9-37) and expressed uninterruptedly in both mRNA Groups. These results suggest that 3' end processing of the rat PIGR gene may involve misalignment, slippage and premature termination of RNA polymerase II. The function of this unusual processing and possible roles of chi-like octamers in quiescent or extrahepatic tissues are discussed. Images PMID:7739889

MM Herculis - An eclipsing binary of the RS CVn

NASA Technical Reports Server (NTRS)

Sowell, J. R.; Hall, D. S.; Henry, G. W.; Burke, E. W., Jr.; Milone, E. F.

1983-01-01

V, B and U differential photoelectric photometry has been obtained for the RS Canum Venaticorum-class eclipsing binary star MM Her, with the light outside the eclipse being Fourier-analyzed to study wave migration and amplitude. These, together with the mean light level of the system, have been monitored from 1976 through 1980. Observations within the eclipse have revealed eclipses to be partial, rather than total as previously thought. The geometric elements of the presently rectified light curve are forced on the pre-1980 light curves and found to be compatible. With these elements, and previously obtained double line radial velocity curves, new absolute dimensions of 1.18 solar masses and 1.58 solar radii are calculated for the hotter star and 1.27 solar masses and 2.83 solar radii for the cooler star. The plotting of color indices on the color-color curve indicates G2V and K2IV spectral types.

A Novel Compact Wideband TSA Array for Near-Surface Ice Sheet Penetrating Radar Applications

NASA Astrophysics Data System (ADS)

Zhang, Feng; Liu, Xiaojun; Fang, Guangyou

2014-03-01

A novel compact tapered slot antenna (TSA) array for near-surface ice sheet penetrating radar applications is presented. This TSA array is composed of eight compact antenna elements which are etched on two 480mm × 283mm FR4 substrates. Each antenna element is fed by a wideband coplanar waveguide (CPW) to coupled strip-line (CPS) balun. The two antenna substrates are connected together with a metallic baffle. To obtain wideband properties, another two metallic baffles are used along broadsides of the array. This array is fed by a 1 × 8 wideband power divider. The measured S11 of the array is less than -10dB in the band of 500MHz-2GHz, and the measured gain is more than 6dBi in the whole band which agrees well with the simulated results.

Worldwide Report, Telecommunications Policy, Research and Development, No. 283.

DTIC Science & Technology

1983-08-10

JPRS 84082 10 August 1983 ;-yry^7S-.-•-■■:■? TT h Worldwide Report TELECOMMUNICATIONS POLICY, RESEARCH AND DEVELOPMENT No. 283 tmC...POLICY, RESEARCH AND DEVELOPMENT No, 283 CONTENTS WORLDWIDE AFFAIRS Satellite Hookup Between Moscow, California TV (Moscow Domestic Television...and mass communi- cations. One even talks about the world turning, from the viewpoint of all-permeating information, into one global village. It

45 CFR 283.6 - If a State wants to be considered for bonus eligibility, what data on abortions must it submit?

Code of Federal Regulations, 2010 CFR

2010-10-01

... eligibility, what data on abortions must it submit? 283.6 Section 283.6 Public Welfare Regulations Relating to... bonus eligibility, what data on abortions must it submit? (a) To be considered further for bonus... information on the number of abortions for calendar year 1995 within two months of this notification. This...

45 CFR 283.9 - What do eligible States need to know to access and use the bonus funds?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 2 2014-10-01 2012-10-01 true What do eligible States need to know to access and use the bonus funds? 283.9 Section 283.9 Public Welfare Regulations Relating to Public Welfare OFFICE... HEALTH AND HUMAN SERVICES IMPLEMENTATION OF SECTION 403(A)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD...

45 CFR 283.9 - What do eligible States need to know to access and use the bonus funds?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false What do eligible States need to know to access and use the bonus funds? 283.9 Section 283.9 Public Welfare Regulations Relating to Public Welfare OFFICE... HEALTH AND HUMAN SERVICES IMPLEMENTATION OF SECTION 403(A)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD...

45 CFR 283.9 - What do eligible States need to know to access and use the bonus funds?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true What do eligible States need to know to access and use the bonus funds? 283.9 Section 283.9 Public Welfare Regulations Relating to Public Welfare OFFICE... HEALTH AND HUMAN SERVICES IMPLEMENTATION OF SECTION 403(A)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD...

45 CFR 283.9 - What do eligible States need to know to access and use the bonus funds?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 2 2012-10-01 2012-10-01 false What do eligible States need to know to access and use the bonus funds? 283.9 Section 283.9 Public Welfare Regulations Relating to Public Welfare OFFICE... HEALTH AND HUMAN SERVICES IMPLEMENTATION OF SECTION 403(A)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD...

45 CFR 283.9 - What do eligible States need to know to access and use the bonus funds?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false What do eligible States need to know to access and use the bonus funds? 283.9 Section 283.9 Public Welfare Regulations Relating to Public Welfare OFFICE... HEALTH AND HUMAN SERVICES IMPLEMENTATION OF SECTION 403(A)(2) OF THE SOCIAL SECURITY ACT BONUS TO REWARD...

45 CFR 283.6 - If a State wants to be considered for bonus eligibility, what data on abortions must it submit?

Code of Federal Regulations, 2012 CFR

2012-10-01

... eligibility, what data on abortions must it submit? 283.6 Section 283.6 Public Welfare Regulations Relating to... bonus eligibility, what data on abortions must it submit? (a) To be considered further for bonus... information on the number of abortions for calendar year 1995 within two months of this notification. This...

45 CFR 283.6 - If a State wants to be considered for bonus eligibility, what data on abortions must it submit?

Code of Federal Regulations, 2013 CFR

2013-10-01

... eligibility, what data on abortions must it submit? 283.6 Section 283.6 Public Welfare Regulations Relating to... bonus eligibility, what data on abortions must it submit? (a) To be considered further for bonus... information on the number of abortions for calendar year 1995 within two months of this notification. This...

45 CFR 283.6 - If a State wants to be considered for bonus eligibility, what data on abortions must it submit?

Code of Federal Regulations, 2014 CFR

2014-10-01

... eligibility, what data on abortions must it submit? 283.6 Section 283.6 Public Welfare Regulations Relating to... bonus eligibility, what data on abortions must it submit? (a) To be considered further for bonus... information on the number of abortions for calendar year 1995 within two months of this notification. This...

45 CFR 283.6 - If a State wants to be considered for bonus eligibility, what data on abortions must it submit?

Code of Federal Regulations, 2011 CFR

2011-10-01

... eligibility, what data on abortions must it submit? 283.6 Section 283.6 Public Welfare Regulations Relating to... bonus eligibility, what data on abortions must it submit? (a) To be considered further for bonus... information on the number of abortions for calendar year 1995 within two months of this notification. This...

49 CFR Appendix to Subpart G of... - Required Knowledge and Skills-Sample Guidelines

Code of Federal Regulations, 2010 CFR

2010-10-01

... knowledge and skills tests that it administers to CDL applicants. This appendix closely follows the... discretion provided their CDL program tests for the general areas of knowledge and skill specified in §§ 383.111 and 383.113. Examples of specific knowledge elements (a) Safe operations regulations. Driver...

77 FR 16435 - Transmission Relay Loadability Reliability Standard

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-21

... are designed to read electrical measurements, such as current, voltage, and frequency, and can be set... an element of the system under its protection, it sends a signal to an interrupting device(s) (such... their relays according to one of thirteen specific settings (sub-parts R1.1 through R1.13) designed to...

NSWC Library of Mathematics Subroutines

DTIC Science & Technology

1990-01-01

sufficiently many zero elements for it to be worthwhile to use special techniques that avoid storing and operating with the zeros.U The scheme adopted by the... general purpose numerical mathematics subroutines began. The subroutines are written in ANSI standard Fortran. This manual describes the subroutines in...PLCOPYDPCOPY ............ ...................... 113 Addition of Polynomials - PADD ,DPADD ............. .................. I.... 115 Subtraction of

Development of an Effective Special Therapy Bed Management System at Walter Reed Army Medical Center.

DTIC Science & Technology

1991-12-01

Patillo, 1990). The administrative support element attempted to pattern itself after the clinical model, hoping to better manage shortages of personnel...Material ManaQement Quarterly, 11(3), 36-48. Thomas, C. (1989). Specialty beds: Decision making made easy. Ostomy -Wound Management, 23, 51-59. Thomson

Conformational Entropy from Slowly Relaxing Local Structure Analysis of 15N-H Relaxation in Proteins: Application to Pheromone Binding to MUP-I in the 283-308 K Temperature Range.

PubMed

Žídek, Lukáš; Meirovitch, Eva

2017-09-21

The slowly relaxing local structure (SRLS) approach is applied to 15 N-H relaxation from the major urinary protein I (MUP-I), and its complex with pheromone 2-sec-butyl-4,5-dihydrothiazol. The objective is to elucidate dynamics, and binding-induced changes in conformational entropy. Experimental data acquired previously in the 283-308 K temperature range are used. The N-H bond is found to reorient globally with correlation time, τ 1,0 , and locally with correlation time, τ 2,0 , where τ 1,0 ≫ τ 2,0 . The local motion is restricted by the potential u = -c 0 2 D 00 2 , where D 00 2 is the Wigner rotation matrix element for L = 2, K = 0, and c 0 2 evaluates the strength of the potential. u yields straightforwardly the order parameter, ⟨D 00 2 ⟩, and the conformational entropy, S k , both given by P eq = exp(-u). The deviation of the local ordering/local diffusion axis from the N-H bond, given by the angle β, is also determined. We find that c 0 2 ≅ 18 ± 4 and τ 2,0 = 0-170 ps for ligand-free MUP-I, whereas c 0 2 ≅ 15 ± 4 and τ 2,0 = 20-270 ps for ligand-bound MUP-I. β is in the 0-10° range. c 0 2 and τ 2,0 decrease, whereas β increases, when the temperature is increased from 283 to 308 K. Thus, SRLS provides physically well-defined structure-related (c 0 2 and ⟨D 00 2 ⟩), motion-related (τ 2,0 ), geometry-related (β), and binding-related (S k ) local parameters, and their temperature-dependences. Intriguingly, upon pheromone binding the conformational entropy of MUP-I decreases at high temperature and increases at low temperature. The very same experimental data were analyzed previously with the model-free (MF) method which yielded "global" (in this context, "relating to the entire 283-308 K range") amplitude (S 2 ) and rate (τ e ) of the local motion, and a phenomenological exchange term (R ex ). S 2 is found to decrease (implying implicitly "global" increase in S k ) upon pheromone binding.

40 CFR 264.283 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.283 Section 264.283 Protection of Environment... characteristics of the wastes, including their potential to migrate through soil or to volatilize or escape into...

Actinide targets for the synthesis of super-heavy elements

DOE PAGES

Roberto, J.; Alexander, Charles W.; Boll, Rose Ann; ...

2015-06-18

Since 2000, six new super-heavy elements with atomic numbers 113 through 118 have been synthesized in hot fusion reactions of 48Ca beams on actinide targets. These target materials, including 242Pu, 244Pu, 243Am, 245Cm, 248Cm, 249Cf, and 249Bk, are available in very limited quantities and require specialized production and processing facilities resident in only a few research centers worldwide. This report describes the production and chemical processing of heavy actinide materials for super-heavy element research, current availabilities of these materials, and related target fabrication techniques. The impact of actinide materials in super-heavy element discovery is reviewed, and strategies for enhancing themore » production of rare actinides including 249Bk, 251Cf, and 254Es are described.« less

Cultural Resources Reconnaissance Along the Cheyenne River Arm of Lake Oahe in Dewey, Haakon, Stanley, and Ziebach Counties, South Dakota. Volume 1. Main Report

DTIC Science & Technology

1988-03-01

of site 39ST282................................227 39 Plan of site 39ST283................................230 40 Detailed plans of Features 1 and 2...268 53 Plan of site 39DW64 .............................. 272 54 Plan of Feature 1, site 39DW64 ................... 273 55 Plan of site 39DW65...facing E ........................... 228 46 Site 39ST283, facing NE .......................... 232 47 Detail of Feature 1, site 39ST283, facing NW

[Census of the renal and dialysis units by Italian Society of Nephrology: structure and organization for renal patient assistance in Italy (2014-2015)].

PubMed

Quintaliani, Giuseppe; Di Luca, Marina; Di Napoli, Anteo; Viglino, Giusto; Postorino, Maurizio; Amore, Alessandro; Andrulli, Simeone; Bellasi, Antonio; Brunori, Giuliano; Buongiorno, Erasmo; Castellino, Santina; D'Amelio, Alessandro; De Nicola, Luca; Gesualdo, Loreto; Di Landro, Domenico; Feriozzi, Sandro; Strippoli, Giovanni; Teatini, Ugo; Santoro, Antonio

2016-01-01

Given the public health challenge and burden of chronic kidney disease, the Italian Society of Nephrology (SIN) promoted a census of the renal and dialysis units to analyse structural and human resources, organizational aspects, activities and workload referring to the year 2014. An online questionnaire, including 64 items exploring structural and human resources, organization aspects, activities and epidemiological data referred to 2014, was sent to chiefs of any renal or dialysis unit. 615 renal units were identified. From these 615 units, 332 were public renal centres (of which 318 centres answered to the census) and 283 were private dialysis centres (of which 113 centres answered to the census). The results show 6 public renal units pmp. Renal biopsies were 4624 (81 pmp). The nephrology beds are about 41 pmp. There are 7.304 nurses working in HD wards, 1.692 in the nephrology wards and only 613 for outpatients clinics. The benchmark data derived from this census show interesting comparisons between centres, regions and groups of regions. These data realised the clinical management of renal disease in Italy.

Identification of the protease cleavage sites in a reconstituted Gag polyprotein of an HERV-K(HML-2) element

PubMed Central

2011-01-01

Background The human genome harbors several largely preserved HERV-K(HML-2) elements. Although this retroviral family comes closest of all known HERVs to producing replication competent virions, mutations acquired during their chromosomal residence have rendered them incapable of expressing infectious particles. This also holds true for the HERV-K113 element that has conserved open reading frames (ORFs) for all its proteins in addition to a functional LTR promoter. Uncertainty concerning the localization and impact of post-insertional mutations has greatly hampered the functional characterization of these ancient retroviruses and their proteins. However, analogous to other betaretroviruses, it is known that HERV-K(HML-2) virions undergo a maturation process during or shortly after release from the host cell. During this process, the subdomains of the Gag polyproteins are released by proteolytic cleavage, although the nature of the mature HERV-K(HML-2) Gag proteins and the exact position of the cleavage sites have until now remained unknown. Results By aligning the amino acid sequences encoded by the gag-pro-pol ORFs of HERV-K113 with the corresponding segments from 10 other well-preserved human specific elements we identified non-synonymous post-insertional mutations that have occurred in this region of the provirus. Reversion of these mutations and a partial codon optimization facilitated the large-scale production of maturation-competent HERV-K113 virus-like particles (VLPs). The Gag subdomains of purified mature VLPs were separated by reversed-phase high-pressure liquid chromatography and initially characterized using specific antibodies. Cleavage sites were identified by mass spectrometry and N-terminal sequencing and confirmed by mutagenesis. Our results indicate that the gag gene product Pr74Gag of HERV-K(HML-2) is processed to yield p15-MA (matrix), SP1 (spacer peptide of 14 amino acids), p15, p27-CA (capsid), p10-NC (nucleocapsid) and two C-terminally encoded glutamine- and proline-rich peptides, QP1 and QP2, spanning 23 and 19 amino acids, respectively. Conclusions Expression of reconstituted sequences of original HERV elements is an important tool for studying fundamental aspects of the biology of these ancient viruses. The analysis of HERV-K(HML-2) Gag processing and the nature of the mature Gag proteins presented here will facilitate further studies of the discrete functions of these proteins and of their potential impact on the human host. PMID:21554716

Identification of the protease cleavage sites in a reconstituted Gag polyprotein of an HERV-K(HML-2) element.

PubMed

George, Maja; Schwecke, Torsten; Beimforde, Nadine; Hohn, Oliver; Chudak, Claudia; Zimmermann, Anja; Kurth, Reinhard; Naumann, Dieter; Bannert, Norbert

2011-05-09

The human genome harbors several largely preserved HERV-K(HML-2) elements. Although this retroviral family comes closest of all known HERVs to producing replication competent virions, mutations acquired during their chromosomal residence have rendered them incapable of expressing infectious particles. This also holds true for the HERV-K113 element that has conserved open reading frames (ORFs) for all its proteins in addition to a functional LTR promoter. Uncertainty concerning the localization and impact of post-insertional mutations has greatly hampered the functional characterization of these ancient retroviruses and their proteins. However, analogous to other betaretroviruses, it is known that HERV-K(HML-2) virions undergo a maturation process during or shortly after release from the host cell. During this process, the subdomains of the Gag polyproteins are released by proteolytic cleavage, although the nature of the mature HERV-K(HML-2) Gag proteins and the exact position of the cleavage sites have until now remained unknown. By aligning the amino acid sequences encoded by the gag-pro-pol ORFs of HERV-K113 with the corresponding segments from 10 other well-preserved human specific elements we identified non-synonymous post-insertional mutations that have occurred in this region of the provirus. Reversion of these mutations and a partial codon optimization facilitated the large-scale production of maturation-competent HERV-K113 virus-like particles (VLPs). The Gag subdomains of purified mature VLPs were separated by reversed-phase high-pressure liquid chromatography and initially characterized using specific antibodies. Cleavage sites were identified by mass spectrometry and N-terminal sequencing and confirmed by mutagenesis. Our results indicate that the gag gene product Pr74Gag of HERV-K(HML-2) is processed to yield p15-MA (matrix), SP1 (spacer peptide of 14 amino acids), p15, p27-CA (capsid), p10-NC (nucleocapsid) and two C-terminally encoded glutamine- and proline-rich peptides, QP1 and QP2, spanning 23 and 19 amino acids, respectively. Expression of reconstituted sequences of original HERV elements is an important tool for studying fundamental aspects of the biology of these ancient viruses. The analysis of HERV-K(HML-2) Gag processing and the nature of the mature Gag proteins presented here will facilitate further studies of the discrete functions of these proteins and of their potential impact on the human host.

Synthesis of Textures Using Simultaneous Autoregressive Models.

DTIC Science & Technology

1981-07-01

CHELLAPPA AFOSR-77-3271 UNCLASSIFIED TR- 1082 AFOSR-TR-81-0795 NL 110~2.8 .113:’I0 111.02. 1111I25 II.4~* 1.6 MICROCOPY R[ SOLUTION ILS1 CHARI ,.TR- 81...NUMBER TR- 1082 . 7. AUTHOR(*) S. CONTRACT OR GRANT NUMBER(&) R. Chella-)pa AFOSR-77-3271 9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT

49 CFR 192.283 - Plastic pipe: Qualifying joining procedures.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Materials Other Than by Welding § 192.283 Plastic pipe: Qualifying joining procedures. (a) Heat fusion... for making plastic pipe joints by a heat fusion, solvent cement, or adhesive method, the procedure...

49 CFR 192.283 - Plastic pipe: Qualifying joining procedures.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Materials Other Than by Welding § 192.283 Plastic pipe: Qualifying joining procedures. (a) Heat fusion... for making plastic pipe joints by a heat fusion, solvent cement, or adhesive method, the procedure...

49 CFR 192.283 - Plastic pipe: Qualifying joining procedures.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Materials Other Than by Welding § 192.283 Plastic pipe: Qualifying joining procedures. (a) Heat fusion... for making plastic pipe joints by a heat fusion, solvent cement, or adhesive method, the procedure...

49 CFR 192.283 - Plastic pipe: Qualifying joining procedures.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Materials Other Than by Welding § 192.283 Plastic pipe: Qualifying joining procedures. (a) Heat fusion... for making plastic pipe joints by a heat fusion, solvent cement, or adhesive method, the procedure...

Synergistic effect of PB2 283M and 526R contributes to enhanced virulence of H5N8 influenza viruses in mice.

PubMed

Wang, Xiao; Chen, Sujuan; Wang, Dandan; Zha, Xixin; Zheng, Siwen; Qin, Tao; Ma, Wenjun; Peng, Daxin; Liu, Xiufan

2017-10-25

Highly pathogenic avian influenza (HPAI) H5N8 virus has caused considerable economic losses to poultry industry and poses a great threat to public health. Our previous study revealed two genetically similar HPAI H5N8 viruses displaying completely different virulence in mice. However, the molecular basis for viral pathogenicity to mammals remains unknown. Herein, we generated a series of reassortants between the two viruses and evaluated their virulence in mice. We demonstrated that 283M in PB2 is a new mammalian virulence marker for H5 viruses and that synergistic effect of amino acid residues 283M and 526R in PB2 is responsible for high virulence of the HPAI H5N8 virus. Analysis of available PB2 sequences showed that PB2 283M is highly conserved among influenza A viruses, while PB2 526R presents in most of human H3N2 and H5N1 isolates. Further study confirmed that the residues 283M and 526R had similar impacts on an HPAI H5N1 virus, suggesting that influenza viruses with both residues may replicate well in mammalian hosts. Together, these results present new insights for synergistic effect of 283M and 526R in PB2 of H5 HPAI virus on virulence to mammalian host, furthering our understanding of the pathogenesis of influenza A virus.

Bloodletting therapy in hemochromatosis: Does it affect trace element homeostasis?

PubMed

Bolann, Bjørn J; Distante, Sonia; Mørkrid, Lars; Ulvik, Rune J

2015-01-01

Hemochromatosis is the most common hereditary disorder in the Nordic population, if left untreated it can result in severe parenchymal iron accumulation. Bloodletting is mainstay treatment. Iron and trace elements partially share cellular uptake and transport mechanisms, and the aim of the present study was to see if bloodletting for hemochromatosis affects trace elements homeostasis. We recruited patients referred for diagnosis and treatment of hemochromatosis, four women and 22 men 23-68 years of age. Thirteen were C282Y homozygote, one was C282Y heterozygote, three were H63D homozygote, seven were compound heterozygote and two had none of the mutations above. Iron and liver function tests were performed; serum levels of trace elements were measured using inductively coupled plasma mass spectrometry. Results before the start of treatment and after normalization of iron parameters were compared. On completion of the bloodlettings the following average serum concentrations increased: Co from 5.6 to 11.5 nmol/L, serum Cu 16.2-17.6 μmol/L, Ni increased from 50.0 to 52.6 nmol/L and Sb from 13.2 to 16.3 nmol/L. Average serum Mn concentration declined from 30.2 to 28.3 nmol/L. All changes were statistically significant (by paired t-test). B, Ba, Cs, Mo, Se, Sr and Zn were not significantly changed. We conclude that bloodlettings in hemochromatosis lead to changes in trace element metabolism, including increased absorption of potentially toxic elements. Copyright © 2014 Elsevier GmbH. All rights reserved.

30 CFR 28.3 - Installation, use, and maintenance of approved fuses.

Code of Federal Regulations, 2010 CFR

2010-07-01

...-CIRCUIT PROTECTION FOR TRAILING CABLES IN COAL MINES General Provisions § 28.3 Installation, use, and... standards prescribed for short-circuit protective devices for trailing cables in Parts 75 and 77, Subchapter...

STS-92 Mission Specialist Lopez-Alegria is ready to drive the M- 113

NASA Technical Reports Server (NTRS)

2000-01-01

Waiting his turn to drive the M-113 is STS-92 Mission Specialist Michael Lopez-Alegria. Part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities, the tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

KSC-00pp1326

NASA Image and Video Library

2000-09-13

With other crew members in the back, STS-92 Mission Specialist Leroy Chiao races the M-113 along the track through the scrub. Driving the M-113 is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter’s payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program

Inferring the Behavior, Concentration and Flux of CO2 from the Suboceanic Mantle from Undegassed Ocean Ridge and Ocean Island Basalts

NASA Astrophysics Data System (ADS)

Michael, P. J.; Graham, D. W.

2015-12-01

We determined glass and vesicle CO2 contents, plus trace element contents for fifty-one ultradepleted mid-ocean ridge basalt (MORB) glasses distributed globally. Sixteen had no vesicles and were volatile undersaturated. Thirty-five had vesicles and were slightly oversaturated. If this latter group lost bubbles during emplacement, then CO2/Ba calculated for the undersaturated group alone is the most reliable and uniform ratio at 98±10, and CO2/Nb is 283±32. If they did not lose bubbles, then CO2/Nb is the most uniform ratio for the entire suite of ultradepleted MORBs at 291±132, while CO2/Ba decreases with incompatible element enrichment. For a wider range of compositions, we used published estimates of CO2 in enriched basalts that retained vesicles e.g., "popping rocks", and from melt inclusions in normal MORBs. As incompatible element enrichment increases, CO2/Nb increases from 283±32 in ultradepleted MORBs to 603±69 in depleted melt inclusions to 936±132 in enriched basalts. In contrast, CO2/Ba is nearly constant at 98±10, 106±24 and 111±11 respectively. This suggests that Ba is the best proxy for estimating CO2 contents of MORBs, with an overall average CO2/Ba = 105±9. Atlantic, Pacific and Indian basalts have similar values. Gakkel ridge has anomalously high Ba and low CO2/Ba. Using the CO2/Ba ratio and an average MORB composition, the CO2 concentration of a primary, average MORB is 2085+473/-427 ppm while primary NMORB has 1840ppm CO2. The annual flux of CO2 from mid-ocean ridges is 1.25±0.16 x 1014 g/yr (0.93 - 1.61 x 1014 g/yr is possible): higher than published estimates that use CO2/3He in MORB and the abyssal ocean 3He flux. This may be accounted for by a CO2/3He ratio that is higher than the commonly accepted MORB ratio of 2x109 due to leverage by more enriched basalts. NMORB mantle has 183 ppm CO2 based on simple melting models. More realistic estimates of depleted mantle composition yield lower estimates of ~60-130ppm, with large uncertainties that depend more on melting models than on CO2/Ba. CO2/Ba is not correlated with isotopic or trace element ratios.

Identifying priorities to improve paediatric in-hospital antimicrobial use by cross-sectional evaluation of prevalence and appropriateness of prescription.

PubMed

Goycochea-Valdivia, Walter Alfredo; Moreno-Ramos, Francisco; Paño-Pardo, José Ramón; Aracil-Santos, Francisco Javier; Baquero-Artigao, Fernando; Del Rosal-Rabes, Teresa; Mellado-Peña, María José; Escosa-García, Luis

2017-11-01

Information about paediatric in-hospital antimicrobial usage and prescribing patterns to guide improvement strategies is scant. We aim to use an evaluation of the prevalence and appropriateness of antimicrobial prescription to identify antimicrobial stewardship priorities in children. A cross-sectional point study was performed on hospitalised paediatric patients in a Spanish tertiary hospital, assessing the prevalence of antimicrobial prescription (PAP) and appropriateness of antimicrobial prescription (AAP). AAP was defined as a correct indication plus an appropriate prescribing pattern (dose, spectrum and interval). Evaluation was performed using established antimicrobial guidelines. Other factors that may have a bearing on antimicrobial prescription were also analysed. A total of 171 patients were included. PAP was 49.7% (85/171) and AAP was 60.9% (91/161). The most common indications for antimicrobial use were antimicrobial prophylaxis (28.3%, 32/113) and pneumonia (8.2%, 8/113). Overall, 161 antimicrobials were prescribed (1.9 antimicrobials per patient): 55.3% (89/161) were empiric, 16.1% (26/161) were targeted and 28.6% (46/161) were prophylactic. Amoxicillin/clavulanate (8.2%, 14/171) and sulfamethoxazole/trimethoprim (8.2%, 14/171) were the most prescribed antimicrobials. The prescription of antifungals (11.7%, 20/171) and antivirals (1.8%, 3/171) was analysed. Major causes of inappropriate antibiotic use were prolonged prescriptions (21.7%, 35/161) and use of agents with an excessively broad coverage spectrum (21.1%, 34/161). PAP and AAP varied between wards and antimicrobials. Measurement of PAP and AAP offers valuable information for detecting priorities in hospital settings and monitoring antimicrobial usage prior to the development of antimicrobial stewardship programmes. In our setting, the main areas for improvement are duration of therapy and proper use of broad-spectrum antimicrobials. Copyright © 2017 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

Questionnaire on Brain Death and Organ Procurement.

PubMed

Hammad, Saleh; Alnammourah, Manal; Almahmoud, Farah; Fawzi, Mais; Breizat, Abdel-Hadi

2017-02-01

The subject of organs for transplant after brain death raises many concerns, including definition and timing of death, how to permit human organ transplant, and the idea of paying for organs. Many ethical concerns are raised regarding regulations and procedures for organ transplant in developing countries. These include where and how to obtain organs and the concept of justice in organ distribution. We administered 2682 questionnaires to 628 men and 2054 women over 24 months (range, 18 to 70 years old). We included people from universities, colleges, and the general public and asked questions on the circumstances of death, the conditions of conversations around organ donation, and reasons for acceptance or refusal of donation. The identical questionnaire, consisting of 8 questions, was administered twice: before and after a teaching session on brain death and organ procurement. The study was approved by our Ethical Review Committee and in accordance with the ethical guidelines of the 1975 Helsinki Declaration. Written informed consent was obtained from all participants. We found that 72.1% understood brain death in the prequestionnaire and 88% understood brain death in the postquestionnaire, with 63.8% versus 68% accepting the concept of brain death, 50.6% versus 58.3% thinking that their religion is against brain death, 11.3% versus 11.3% carrying a donor card, 50.7% versus 58.9% wanting to carry a donor card, 46.4% versus 56.4% agreeing to give consent for organ donation if a relative was diagnosed with brain death, 28.3% versus 50% aware of the laws and regulations concerning brain death and organ donation and transplant in Jordan, and 35.4% versus 40% in agreement with the Presumed Consent Law, respectively. In Jordan, along with legal requirements concerning brain death and organ donation and transplant, there is a lack of acceptance of organ donation after brain death, necessitating further work and activities to achieve self-sufficiency from donated organs.

[Radiological control intraoperatory of a surgical piece in non palpable breast lesions].

PubMed

Ruvalcaba Limón, Eva; Espejo Fonseca, Ruby; Bautista Piña, Verónica; Madero Preciado, Luis; Capurso Garcia, Marino; Serratos Garduño, José Eduardo; Hohenstein, Fernando Guisa; Rodríguez Cuevas, Sergio

2009-09-01

nonconcrete the mammary injuries are frequent in programs of detection of breast cancer, estereotaxic or ecographic marking is required to realize its split. The intrasurgical radiation control of the surgical piece is indispensable to evaluate the margins of the mammary cancer. to determine the effectiveness of the intrasurgical radiation control of the surgical piece in nonconcrete mammary injuries to diminish the surgical reinterventions to extend margins. women with nonconcrete mammary injuries to those who biopsy by split became, previous marking and intraoperating radiation control of the surgical piece to value margins (suitable margin the same or major of 10 mm, smaller inadequate margin of 10 mm). Intrasurgical reesicion in inadequate radiological margins became. The demographic characteristics, masto-ecographics images, histopathology of the injuries and the radiological-histopatol6gica correlation of the margins studied. Cross-sectional, prospective and descriptive study. 103 patients with 113 nonconcrete mammary injuries included themselves, with age average of 51,35 (32-73) years. In all the injuries the intrasurgical radiation control became of the surgical piece. The prevalence of mammary cancer was of 28.3% (32/113), that corresponds to stellar images (42.8%), suspicious microcalcifications with density (39.2%), microcalcifications (31.2%) and nodules (20%). Of the 32 cancers, 16 had inadequate radiological margins that required intraoperating reescision; suitable histopatologic margins in 100% were obtained (16/16). The 16 (62.5%) cancers without intraoperating reescisi6n by suitable radiological margins had suitable histopatologic margins and 37.5% (6/16) inadequate ones that required surgical reinterventionn to control the margins. The discrepancy between margins was related to microcalcifications in 83.3% of the injuries. the intrasurgical radiation control of the surgical piece is effective to evaluate margins; the intrasurgical reescisión changed inadequate margins to suitable in 50% (16/32) of the cancers; only 18.7% (6/32) of the total of cases required another surgery to control the margins.

Investigation of dissipation elements in a fully developed turbulent channel flow by tomographic particle-image velocimetry

NASA Astrophysics Data System (ADS)

Schäfer, L.; Dierksheide, U.; Klaas, M.; Schröder, W.

2011-03-01

A new method to describe statistical information from passive scalar fields has been proposed by Wang and Peters ["The length-scale distribution function of the distance between extremal points in passive scalar turbulence," J. Fluid Mech. 554, 457 (2006)]. They used direct numerical simulations (DNS) of homogeneous shear flow to introduce the innovative concept. This novel method determines the local minimum and maximum points of the fluctuating scalar field via gradient trajectories, starting from every grid point in the direction of the steepest ascending and descending scalar gradients. Relying on gradient trajectories, a dissipation element is defined as the region of all the grid points, the trajectories of which share the same pair of maximum and minimum points. The procedure has also been successfully applied to various DNS fields of homogeneous shear turbulence using the three velocity components and the kinetic energy as scalar fields [L. Wang and N. Peters, "Length-scale distribution functions and conditional means for various fields in turbulence," J. Fluid Mech. 608, 113 (2008)]. In this spirit, dissipation elements are, for the first time, determined from experimental data of a fully developed turbulent channel flow. The dissipation elements are deduced from the gradients of the instantaneous fluctuation of the three velocity components u', v', and w' and the instantaneous kinetic energy k', respectively. The measurements are conducted at a Reynolds number of 1.7×104 based on the channel half-height δ and the bulk velocity U. The required three-dimensional velocity data are obtained investigating a 17.75×17.75×6 mm3 (0.355δ×0.355δ×0.12δ) test volume using tomographic particle-image velocimetry. Detection and analysis of dissipation elements from the experimental velocity data are discussed in detail. The statistical results are compared to the DNS data from Wang and Peters ["The length-scale distribution function of the distance between extremal points in passive scalar turbulence," J. Fluid Mech. 554, 457 (2006); "Length-scale distribution functions and conditional means for various fields in turbulence," J. Fluid Mech. 608, 113 (2008)]. Similar characteristics have been found especially for the pdf's of the large dissipation element length regarding the exponential decay. In agreement with the DNS results, over 99% of the experimental dissipation elements possess a length that is smaller than three times the average element length.

46 CFR 283.1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-10-01

... working capital. However, this policy also takes into consideration the operators' need to attract new... POLICY FOR OPERATORS RECEIVING OPERATING-DIFFERENTIAL SUBSIDY § 283.1 Purpose. (a) The rules of this part... marine. The policy contained herein takes into consideration the operators' contractual obligations to...

6. BUILDING 283, WEST SIDE OF THE GARAGE ADDITION (CA.1947) ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. BUILDING 283, WEST SIDE OF THE GARAGE ADDITION (CA.1947) ON LEFT, NORTH SIDE OF CA.1947-1950 ADDITION ON RIGHT. - Presidio of San Francisco, Warehouse & Auto Shop, Crissy Field North cantonment, San Francisco, San Francisco County, CA

In-feed use of heavy metal micronutrients in U.S. swine production systems and its role in persistence of multidrug-resistant salmonellae.

PubMed

Medardus, Julius J; Molla, Bayleyegn Z; Nicol, Matthew; Morrow, W Morgan; Rajala-Schultz, Paivi J; Kazwala, Rudovick; Gebreyes, Wondwossen A

2014-04-01

The study aimed to characterize the role of heavy metal micronutrients in swine feed in emergence of heavy-metal-tolerant and multidrug-resistant Salmonella organisms. We conducted a longitudinal study in 36 swine barns over a 2-year period. The feed and fecal levels of Cu(2+) and Zn(2+) were measured. Salmonella was isolated at early and late finishing. MICs of copper sulfate and zinc chloride were measured using agar dilution. Antimicrobial susceptibility was tested using the Kirby-Bauer method, and 283 isolates were serotyped. We amplified pcoA and czcD genes that encode Cu(2+) and Zn(2+) tolerance, respectively. Of the 283 isolates, 113 (48%) showed Cu(2+) tolerance at 24 mM and 164 (58%) showed Zn(2+) tolerance at 8 mM. In multivariate analysis, serotype and source of isolates were significantly associated with Cu(2+) tolerance (P < 0.001). Fecal isolates were more likely to be Cu(2+) tolerant than those of feed origin (odds ratio [OR], 27.0; 95% confidence interval [CI], 2.8 to 250; P = 0.0042) or environmental origin (OR, 5.8), implying the significance of gastrointestinal selective pressure. Salmonella enterica serotypes Typhimurium and Heidelberg, highly significant for public health, had higher odds of having >20 mM MICs of Cu(2+) than did "other" serotypes. More than 60% of Salmonella isolates with resistance type (R-type) AmStTeKm (32 of 53) carried pcoA; only 5% with R-type AmClStSuTe carried this gene. czcD gene carriage was significantly associated with a higher Zn(2+) MIC (P < 0.05). The odds of having a high Zn(2+) MIC (≥8 mM) were 14.66 times higher in isolates with R-type AmClStSuTe than in those with R-type AmStTeKm (P < 0.05). The findings demonstrate strong association between heavy metal tolerance and antimicrobial resistance, particularly among Salmonella serotypes important in public health.

In-Feed Use of Heavy Metal Micronutrients in U.S. Swine Production Systems and Its Role in Persistence of Multidrug-Resistant Salmonellae

PubMed Central

Medardus, Julius J.; Molla, Bayleyegn Z.; Nicol, Matthew; Morrow, W. Morgan; Rajala-Schultz, Paivi J.; Kazwala, Rudovick

2014-01-01

The study aimed to characterize the role of heavy metal micronutrients in swine feed in emergence of heavy-metal-tolerant and multidrug-resistant Salmonella organisms. We conducted a longitudinal study in 36 swine barns over a 2-year period. The feed and fecal levels of Cu2+ and Zn2+ were measured. Salmonella was isolated at early and late finishing. MICs of copper sulfate and zinc chloride were measured using agar dilution. Antimicrobial susceptibility was tested using the Kirby-Bauer method, and 283 isolates were serotyped. We amplified pcoA and czcD genes that encode Cu2+ and Zn2+ tolerance, respectively. Of the 283 isolates, 113 (48%) showed Cu2+ tolerance at 24 mM and 164 (58%) showed Zn2+ tolerance at 8 mM. In multivariate analysis, serotype and source of isolates were significantly associated with Cu2+ tolerance (P < 0.001). Fecal isolates were more likely to be Cu2+ tolerant than those of feed origin (odds ratio [OR], 27.0; 95% confidence interval [CI], 2.8 to 250; P = 0.0042) or environmental origin (OR, 5.8), implying the significance of gastrointestinal selective pressure. Salmonella enterica serotypes Typhimurium and Heidelberg, highly significant for public health, had higher odds of having >20 mM MICs of Cu2+ than did “other” serotypes. More than 60% of Salmonella isolates with resistance type (R-type) AmStTeKm (32 of 53) carried pcoA; only 5% with R-type AmClStSuTe carried this gene. czcD gene carriage was significantly associated with a higher Zn2+ MIC (P < 0.05). The odds of having a high Zn2+ MIC (≥8 mM) were 14.66 times higher in isolates with R-type AmClStSuTe than in those with R-type AmStTeKm (P < 0.05). The findings demonstrate strong association between heavy metal tolerance and antimicrobial resistance, particularly among Salmonella serotypes important in public health. PMID:24487542

The effect of advanced maternal age on maternal and neonatal outcomes of placenta previa: A register-based cohort study.

PubMed

Roustaei, Zahra; Vehviläinen-Julkunen, Katri; Tuomainen, Tomi-Pekka; Lamminpää, Reeta; Heinonen, Seppo

2018-05-19

Advanced maternal age (AMA) at the time of delivery generally worsens obstetric outcomes, but its effects on specific pregnancy problems, such as placenta previa, have not been adequately assessed. Therefore, the objective of the study was to explore the effect of AMA on adverse maternal and neonatal outcomes among pregnancies complicated by placenta previa. The study was a register-based cohort study using data of three Finnish health registries, including information of 283 324 women and their newborns. Separate multivariable logistic regression modeling was performed for women under age 35 and women aged 35 or older to assess the association between placenta previa and adverse maternal and neonatal outcomes. Furthermore, interactions between maternal age and placenta previa were tested. A total of 283 324 deliveries of which 714 (0.3%) were complicated by placenta previa. Adverse maternal and neonatal outcomes increased in women with placenta previa, with different patterns across age groups. The adjusted odds ratios and 95% confidence intervals for AMA and young women with previa were 7.3 (5.0-10.6) and 6.8 (5.2-8.9) in blood transfusion, 11.3 (5.4-23.3) and 10.9 (6.1-19.6) in placental abruption. In neonatal outcomes the adjusted odds ratios for AMA and young women with placenta previa were 8.8 (6.6-11.6) and 11.7 (9.7-14.1) in preterm birth <37 weeks, 4.0 (3.0-5.3) and 4.9 (4.1-5.9) in neonatal intensive care unit (NICU) admission, 4.0 (2.8-5.7) and 5.9 (4.7-7.4) low birth weight <2500 g, 2.7 (1.5-4.9) and 3.3 (2.2-5.0) in low Apgar score at 5 min. The joint effects of maternal age and placenta previa on the risk of adverse maternal and neonatal outcomes were non-significant. The risk of adverse maternal and neonatal outcomes for women with placenta previa was not substantially affected by maternal age if their different risk profiles were taken into account. Copyright © 2018 Elsevier B.V. All rights reserved.

How elements up to 118 were reached and how to go beyond

NASA Astrophysics Data System (ADS)

Düllmann, Christoph E.

2017-11-01

The new superheavy elements with Z=113, 115, 117, and 118 were recently accepted into the periodic table and have been named. Elements with Z≥112 are predominantly produced in 48Ca-induced fusion reactions on actinide targets. This pathway is exhausted at Z=118 due to the lack of target materials with sufficiently high proton number to reach elements with Z≥119. Search experiments for yet heavier elements were performed at GSI Darmstadt and FLNR Dubna. The reactions 50Ti + 249Bk, which leads to Z=119, as well as 64Ni + 238U, 58Fe + 244Pu, 54Cr + 248Cm, and 50Ti + 249Cf, leading to Z=120, have been studied. Despite a total duration of these experiments of more than one year, neither succeeded in the identification of a new element. To obtain improved guidance for better-informed search experiments, nuclear reaction studies appear necessary and have recently started. Also technical advances will be an important pillar to this end. At GSI, work towards a new continuous-wave linear accelerator is ongoing and is briefly described.

Grazing incidence reflection coefficients of rhodium, osmium, platinum, and gold from 50 to 300 A

NASA Technical Reports Server (NTRS)

Hettrick, M. C.; Edelstein, J.; Flint, S. A.

1985-01-01

Reflectance measurements were made of several metals illuminated from various angles with light at 14 wavelengths in the interval 46.5-283 A. The metals, Rh, Os, Pt and Au were deposited as 125 A films on a binding substrate through electron beam epitaxy. Measurements were made with a grazing incidence monochromator and a reflectometer. The data generally showed lowered reflectance with increasing angles of illumination and shorter wavelengths. The reflectance peak, however, was located at wavelengths of 100-160 A, particularly at large grazing incidences. The wavelengths correspond with the 5p to epsilon-d transition in all of the elements. Rh displayed the highest overall reflectance, and both Rh and Os were more efficient than Au or Pt.

7 CFR 283.3 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Indian tribe determined by the Secretary to be capable of effectively administering a Food Stamp Program... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM APPEALS OF QUALITY CONTROL (âQCâ) CLAIMS General § 283.3...

7 CFR 283.3 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Indian tribe determined by the Secretary to be capable of effectively administering a Food Stamp Program... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM APPEALS OF QUALITY CONTROL (âQCâ) CLAIMS General § 283.3...

47 CFR 25.283 - End-of-life disposal.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Technical Operations § 25.283 End-of-life disposal. (a) Geostationary orbit space stations. Unless otherwise explicitly specified in an authorization, a space station authorized to operate in the geostationary... operate in the geostationary satellite orbit under this part may operate using its authorized tracking...

47 CFR 25.283 - End-of-life disposal.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Technical Operations § 25.283 End-of-life disposal. (a) Geostationary orbit space stations. Unless otherwise explicitly specified in an authorization, a space station authorized to operate in the geostationary... operate in the geostationary satellite orbit under this part may operate using its authorized tracking...

47 CFR 25.283 - End-of-life disposal.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Technical Operations § 25.283 End-of-life disposal. (a) Geostationary orbit space stations. Unless otherwise explicitly specified in an authorization, a space station authorized to operate in the geostationary... operate in the geostationary satellite orbit under this part may operate using its authorized tracking...

Structures to Resist the Effects of Accidental Explosions

DTIC Science & Technology

1990-11-01

Mott, R.I., A Theory of Fragmentation, Army Operational Research Group Memorandun, 113-AC-6427, Great Britain, 1943. 77. Non -Nuclear Weapons Effects...58.1. General Elements which protect non -sensitive explosives may be designed for controlled post-failure fragments with a substantial cost savings...6-49.3.2. Platform Characteristics A platform for group mounted systems offers great flexibility in controlling the center of gravity of the

40 CFR 52.283 - Interstate Transport.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.283 Interstate Transport. (a) Approval. On November 16, 2007, the California Air Resources Board submitted the “Interstate Transport State... Act section 110(a)(2)(D)(i) for the State of California (September 21, 2007)” (“2007 Transport SIP...

40 CFR 52.283 - Interstate Transport.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.283 Interstate Transport. (a) Approval. On November 16, 2007, the California Air Resources Board submitted the “Interstate Transport State... Act section 110(a)(2)(D)(i) for the State of California (September 21, 2007)” (“2007 Transport SIP...

40 CFR 52.283 - Interstate Transport.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.283 Interstate Transport. (a) Approval. On November 16, 2007, the California Air Resources Board submitted the “Interstate Transport State... Act section 110(a)(2)(D)(i) for the State of California (September 21, 2007)” (“2007 Transport SIP...

47 CFR 0.283 - Authority delegated.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Delegations of Authority Chief, Media Bureau § 0.283 Authority delegated. The Chief, Media Bureau, is delegated authority to perform all...) of the Communications Act of 1934, as amended, in amounts of more than $20,000. [67 FR 13220, Mar. 21...

7 CFR 283.26 - Request that appeals be handled under procedures in subpart B for appeals of QC claims of $50,000...

Code of Federal Regulations, 2011 CFR

2011-01-01

... the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE FOOD... date established for the conclusion of any discovery pursuant to § 283.29, a motion that its appeal be...

18 CFR 284.283 - Point of unbundling.

Code of Federal Regulations, 2011 CFR

2011-04-01

..., DEPARTMENT OF ENERGY OTHER REGULATIONS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES Blanket Certificates Authorizing Certain Natural Gas Sales by Interstate Pipelines § 284.283 Point...

Biological and genetic characterization of Cryptosporidium spp. and Giardia duodenalis isolates from five hydrographical basins in northern Portugal.

PubMed

Almeida, André; Moreira, Maria João; Soares, Sónia; de Lurdes Delgado, Maria; Figueiredo, João; Magalhães, Elisabete Silva; Castro, António; Viana Da Costa, Alexandra; Correia da Costa, José Manuel

2010-06-01

To understand the situation of water contamination with Cryptosporidium spp. and Giardia spp. in the northern region of Portugal, we have established a long-term program aimed at pinpointing the sources of surface water and environmental contamination, working with the water-supply industry. Here, we describe the results obtained with raw water samples collected in rivers of the 5 hydrographical basins. A total of 283 samples were analyzed using the Method 1623 EPA, USA. Genetic characterization was performed by PCR and sequencing of genes 18S rRNA of Cryptosporidium spp. and beta-giardin of Giardia spp. Infectious stages of the protozoa were detected in 72.8% (206 of 283) of the water samples, with 15.2% (43 of 283) positive for Giardia duodenalis cysts, 9.5% (27 of 283) positive for Cryptosporidium spp. oocysts, and 48.1% (136 of 283) samples positive for both parasites. The most common zoonotic species found were G. duodenalis assemblages A-I, A-II, B, and E genotypes, and Cryptosporidium parvum, Cryptosporidium andersoni, Cryptosporidium hominis, and Cryptosporidium muris. These results suggest that cryptosporidiosis and giardiasis are important public health issues in northern Portugal. To the authors' knowledge, this is the first report evaluating the concentration of environmental stages of Cryptosporidium and Giardia in raw water samples in the northern region of Portugal.

MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation

PubMed Central

Huang, Y; Thoms, JAI; Tursky, ML; Knezevic, K; Beck, D; Chandrakanthan, V; Suryani, S; Olivier, J; Boulton, A; Glaros, EN; Thomas, SR; Lock, RB; MacKenzie, KL; Bushweller, JH; Wong, JWH; Pimanda, JE

2018-01-01

Aberrant ERG (v-ets avian erythroblastosis virus E26 oncogene homolog) expression drives leukemic transformation in mice and high expression is associated with poor patient outcomes in acute myeloid leukemia (AML) and T-acute lymphoblastic leukemia (T-ALL). Protein phosphorylation regulates the activity of many ETS factors but little is known about ERG in leukemic cells. To characterize ERG phosphorylation in leukemic cells, we applied liquid chromatography coupled tandem mass spectrometry and identified five phosphorylated serines on endogenous ERG in T-ALL and AML cells. S283 was distinct as it was abundantly phosphorylated in leukemic cells but not in healthy hematopoietic stem and progenitor cells (HSPCs). Overexpression of a phosphoactive mutant (S283D) increased expansion and clonogenicity of primary HSPCs over and above wild-type ERG. Using a custom antibody, we screened a panel of primary leukemic xenografts and showed that ERG S283 phosphorylation was mediated by mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling and in turn regulated expression of components of this pathway. S283 phosphorylation facilitates ERG enrichment and transactivation at the ERG +85 HSPC enhancer that is active in AML and T-ALL with poor prognosis. Taken together, we have identified a specific post-translational modification in leukemic cells that promotes progenitor proliferation and is a potential target to modulate ERG-driven transcriptional programs in leukemia. PMID:27055868

International comparison CCQM-K113—noble gas mixture

NASA Astrophysics Data System (ADS)

Lim, Jeong Sik; Lee, Jinbok; Moon, Dongmin; Tshilongo, James; Qiao, Han; Shuguo, Hu; Tiqiang, Zhang; Kelley, Michael E.; Rhoderick, George C.; Konopelko, L. A.; Kolobova, A. V.; Vasserman, I. I.; Zavyalov, S. V.; Gromova, E. V.; Efremova, O. V.

2017-01-01

Noble gases are one of the key elements used in the various processes of the bulbs industry, automotive industry, space industry, lasers industry, display industry as well as the semiconductor industry. Considering continuous growth, the provision of a reliable standard is required for those industries to improve their productivity. In this report, a result of the key comparison, CCQM-K113: noble gas mixture, is presented. Nominal amount-of-substance fractions of argon, neon, krypton, and xenon in helium are 20, 10, 2, and 1 cmol/mol, respectively. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

STS-92 Mission Specialist Chiao is ready to drive the M-113

NASA Technical Reports Server (NTRS)

2000-01-01

STS-92 Mission Specialist Leroy Chiao gets into the driver's side for his turn to drive the M-113, part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. Behind him are Pilot Pam Melroy (left) and Mission Specialist Michael Lopez-Alegria. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

STS-92 Mission Specialist Wisoff is ready to drive the M-113

NASA Technical Reports Server (NTRS)

2000-01-01

STS-92 Mission Specialist Jeff Wisoff happily anticipates his chance to drive the M-113 he is in. Behind him are Commander Brian Duffy (left) and Mission Specialist Leroy Chiao, along with other crew members. Part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities, the tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

Comparing consequences of right and left unilateral neglect in a stroke rehabilitation population.

PubMed

Wee, Joy Y M; Hopman, Wilma M

2008-11-01

This article details right and left unilateral neglect (UN) in a stroke rehabilitation population. This prospective observational cohort study documented hemipersonal neglect and hemispatial neglect in 309 of 325 stroke rehabilitation patients consecutively admitted over a 28-month period. Shoulder-hand complications, safety concerns, length of stay, discharge function, and discharge destination were documented. Of the 85 with right UN and 113 with left UN, 17.7% had expressive aphasia, and 17.7% had mixed or receptive aphasia. Hemispatial neglect was associated with hemianopsia (29.2% and 31.8% for right and left, respectively). Having both hemipersonal neglect and hemispatial neglect was related to greater safety risk (46.9% vs. 24.3%), greater incidence of shoulder-hand complications (28.3% vs. 9.9%), lower FIM scores (>10 points lower), longer length of stay (8 days), and less likelihood of discharge to home (67.3% vs. 87.4%) than subjects without UN. Results were similar for those with right and left UN. Right and left UN occur after stroke, can be detected even in the presence of aphasia, and are associated with shoulder-hand problems, lower discharge function, and lower likelihood of discharge home. Having both hemispatial neglect and hemipersonal neglect impacts people more than having either type of UN alone.

21 CFR 556.283 - Florfenicol.

Code of Federal Regulations, 2013 CFR

2013-04-01

..., FEEDS, AND RELATED PRODUCTS TOLERANCES FOR RESIDUES OF NEW ANIMAL DRUGS IN FOOD Specific Tolerances for Residues of New Animal Drugs § 556.283 Florfenicol. (a) Acceptable daily intake (ADI). The ADI for total...) Liver (the target tissue). The tolerance for florfenicol amine (the marker residue) is 3.7 parts per...

21 CFR 556.283 - Florfenicol.

Code of Federal Regulations, 2014 CFR

2014-04-01

..., FEEDS, AND RELATED PRODUCTS TOLERANCES FOR RESIDUES OF NEW ANIMAL DRUGS IN FOOD Specific Tolerances for Residues of New Animal Drugs § 556.283 Florfenicol. (a) Acceptable daily intake (ADI). The ADI for total...) Liver (the target tissue). The tolerance for florfenicol amine (the marker residue) is 3.7 parts per...

21 CFR 556.283 - Florfenicol.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., FEEDS, AND RELATED PRODUCTS TOLERANCES FOR RESIDUES OF NEW ANIMAL DRUGS IN FOOD Specific Tolerances for Residues of New Animal Drugs § 556.283 Florfenicol. (a) Acceptable daily intake (ADI). The ADI for total...) Liver (the target tissue). The tolerance for florfenicol amine (the marker residue) is 3.7 parts per...

7 CFR 283.2 - Scope and applicability.

Code of Federal Regulations, 2010 CFR

2010-01-01

... agencies of Food and Nutrition Service quality control (QC) claims for Fiscal Year (“FY”) 1986 and... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE FOOD STAMP AND FOOD DISTRIBUTION PROGRAM APPEALS OF QUALITY CONTROL (âQCâ) CLAIMS General § 283.2...

Mobilization and Defense Management Technical Reports Series. Mobilization Studies Program Report. Selective Service Boards. Will They Be Ready?

DTIC Science & Technology

1983-05-01

Element (W)I (W2)2 Factors Male 87.5 81.1 +6.4 Sex Female 12.5 18.9 -6.4 Married to.@ 81.7 +18.3 Marital Status Single 6.0 18.3 -18.3 ( 30 0.8 6.9 -6.9...March 1982. i0 ~16l Table 2.1 Demographic Data on Local Boards. (33:12) Number of Local Boards 2,113 Board Positions 16,560 Sex of Board membe s...Effort and ~Reward (n - 175) Actual Expected Effort Response Response Reward Element (%)I (,) 2 Factor3 Male 83.9 81.1 +2.8 Sex Female 16.1 18.9 -2.8

Structure, age, and ore potential of the Burpala rare-metal alkaline massif, northern Baikal region

NASA Astrophysics Data System (ADS)

Vladykin, N. V.; Sotnikova, I. A.; Kotov, A. B.; Yarmolyuk, V. V.; Sal'nikova, E. B.; Yakovleva, S. Z.

2014-07-01

The Burpala alkaline massif is a unique geological object. More than 50 Zr, Nb, Ti, Th, Be, and REE minerals have been identified in rare-metal syenite of this massif. Their contents often reach tens of percent, and concentrations of rare elements in rocks are as high as 3.6% REE, 4% Zr, 0.5% Y, 0.5% Nb, 0.5% Th, and 0.1% U. Geological and geochemical data show that all rocks in the Burpala massif are derivatives of alkaline magma initially enriched in rare elements. These rocks vary in composition from shonkinite, melanocratic syenite, nepheline and alkali syenites to alaskite and alkali granite. The extreme products of magma fractionation are rare-metal pegmatites, apatite-fluorite rocks, and carbonatites. The primary melts were related to the enriched EM-2 mantle source. The U-Pb zircon ages of pulaskite (main intrusive phase) and rare-metal syenite (vein phase) are estimated at 294 ± 1 and 283 ± 8 Ma, respectively. The massif was formed as a result of impact of the mantle plume on the active continental margin of the Siberian paleocontinent.

46 CFR 283.5 - Notification and reporting requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... present value of Capitalized Lease Obligations as defined in § 283.2(b), excluding that portion of any...-term debt and net worth, and shall conform to the definitions of such items as contained herein. As appropriate, reports shall include the following: (1) The ratio of debt to equity, floor net worth and prior...

46 CFR 283.5 - Notification and reporting requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... present value of Capitalized Lease Obligations as defined in § 283.2(b), excluding that portion of any...-term debt and net worth, and shall conform to the definitions of such items as contained herein. As appropriate, reports shall include the following: (1) The ratio of debt to equity, floor net worth and prior...

18 CFR 367.2830 - Account 283, Accumulated deferred income taxes-Other.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Account 283, Accumulated deferred income taxes-Other. 367.2830 Section 367.2830 Conservation of Power and Water Resources... COMPANY ACT OF 2005, FEDERAL POWER ACT AND NATURAL GAS ACT UNIFORM SYSTEM OF ACCOUNTS FOR CENTRALIZED...

Trace element geochemistry of Manilkara zapota (L.) P. Royen, fruit from winder, Balochistan, Pakistan in perspective of medical geology.

PubMed

Hamza, Salma; Naseem, Shahid; Bashir, Erum; Rizwani, Ghazala H; Hina, Bushra

2013-07-01

An integrated study of rocks, soils and fruits of Manilkara zapota (L.) (Sapotaceae) of Winder area have been carried out to elaborate trace elements relationship between them. The igneous rocks of the study area have elevated amount of certain trace elements, upon weathering these elements are concentrated in the soil of the area. The trace elements concentration in the soil were found in the range of 0.8-197 for Fe, 1.23-140 for Mn, 0.03-16.7 for Zn, 0.07-9.8 for Cr, 0.05-2.0 for Co, 0.52-13.3 for Ni, 0.03-8.8 for Cu, 0.08-10.55 for Pb and 0.13-1.8μg/g for Cd. The distribution pattern of elements in the rocks and soils reflected genetic affiliation. Promising elements of edible part of the fruit were Fe (14.17), Mn (1.49), Cr (2.96), Ni (1.13), Co (0.92), Cu (1.70) and Zn (1.02μg/g). The concentration of these elements in the fruits is above the optimum level of recommended dietary intake, probably due to this, disorder in the human health is suspected in the inhabitants of the area.

Long-term control of HIV-1 in hemophiliacs carrying slow-progressing allele HLA-B*5101.

PubMed

Kawashima, Yuka; Kuse, Nozomi; Gatanaga, Hiroyuki; Naruto, Takuya; Fujiwara, Mamoru; Dohki, Sachi; Akahoshi, Tomohiro; Maenaka, Katsumi; Goulder, Philip; Oka, Shinichi; Takiguchi, Masafumi

2010-07-01

HLA-B*51 alleles are reported to be associated with slow disease progression to AIDS, but the mechanism underlying this association is still unclear. In the present study, we analyzed the effect of HLA-B*5101 on clinical outcome for Japanese hemophiliacs who had been infected with HIV-1 before 1985 and had been recruited in 1998 for this study. HLA-B*5101(+) hemophiliacs exhibited significantly slow progression. The analysis of HLA-B*5101-restricted HIV-1-specific cytotoxic T-lymphocyte (CTL) responses to 4 HLA-B*-restricted epitopes in 10 antiretroviral-therapy (ART)-free HLA-B*5101(+) hemophiliacs showed that the frequency of Pol283-8-specific CD8(+) T cells was inversely correlated with the viral load, whereas the frequencies of CD8(+) T cells specific for 3 other epitopes were positively correlated with the viral load. The HLA-B*5101(+) hemophiliacs whose HIV-1 replication had been controlled for approximately 25 years had HIV-1 possessing the wild-type Pol283-8 sequence or the Pol283-8V mutant, which does not critically affect T-cell recognition, whereas other HLA-B*5101(+) hemophiliacs had HIV-1 with escape mutations in this epitope. The results suggest that the control of HIV-1 over approximately 25 years in HLA-B*5101-positive hemophiliacs is associated with a Pol283-8-specific CD8(+) T-cell response and that lack of control of HIV-1 is associated with the appearance of Pol283-8-specific escape mutants.

Dietary intake of trace elements, minerals, and vitamins of patients on chronic hemodialysis.

PubMed

Bossola, Maurizio; Di Stasio, Enrico; Viola, Antonella; Leo, Alessandra; Carlomagno, Giusy; Monteburini, Tania; Cenerelli, Stefano; Santarelli, Stefano; Boggi, Rolando; Miggiano, Giacinto; Vulpio, Carlo; Mele, Cristina; Tazza, Luigi

2014-04-01

We aimed to estimate dietary intakes of trace elements, minerals, and vitamins in hemodialysis patients (HDP) of three centers in one metropolitan and two urban areas of Italy. Daily dietary intake was assessed using a 3-day diet diary in 128 HDP. Mean daily intakes of trace elements were as follows: zinc, 7.6 ± 5.4 mg; copper, 14.3 ± 11.8 mg; selenium, 28.3 ± 18.1 μg; and iron, 7.2 ± 4.1 mg (7.8 ± 2.6 mg in women, 6.9 ± 2.4 mg in men). The distribution of patients by daily intakes of trace elements showed most were under the recommended values, with the exception of copper intake, which was much higher. Mean daily intakes of minerals were as follows: magnesium, 174.4 ± 94.3 mg; phosphorus, 842.6 ± 576.8 mg; calcium, 371.8 ± 363.7 mg; potassium, 1,616.2 ± 897.3 mg; and sodium, 1,350 ± 1,281 mg. Mean daily intakes of vitamins were as follows: vitamin A, 486.1 ± 544.6 μg; vitamin B1, 0.86 ± 0.7 mg; vitamin B2, 1.1 ± 0.7 mg; vitamin B3, 13.3 ± 8.1 mg; vitamin C, 47.8 ± 50.3 mg; and vitamin E, 9.5 ± 3.6 mg. The distribution of patients by daily intakes of vitamins showed most were under the recommended values. Daily intakes of trace elements and vitamins were similar among the three centers and did not differ between dialysis and non-dialysis days. Many HDP have daily dietary intakes of trace elements and vitamins below the recommended values, whereas the intake of copper is much higher.

Menstrual cycle perturbation by organohalogens and elements in the Cree of James Bay, Canada.

PubMed

Wainman, Bruce C; Kesner, James S; Martin, Ian D; Meadows, Juliana W; Krieg, Edward F; Nieboer, Evert; Tsuji, Leonard J

2016-04-01

Persistent organohalogens (POHs) and metals have been linked to alterations in menstrual cycle function and fertility in humans. The Cree First Nations people living near James Bay in Ontario and Quebec, Canada, have elevated levels of POHs, mercury and lead compared to other Canadians. The present study examines the interrelationships between selected POHs and elements on menstrual cycle function in these Cree women. Menstrual cycle characteristics were derived from structured daily diaries and endocrine measurements from daily urine samples collected during one cycle for 42 women age 19-42. We measured 31 POHs in blood plasma and 18 elements in whole blood, for 31 of the participants. POHs and elements detected in ≥ 70% of the participants were transformed by principal component (PC) analysis to reduce the contaminant exposure data to fewer, uncorrelated PCA variables. Multiple regression analysis revealed that, after adjusting for confounders, PC-3 values showed significant negative association with cycle length, after adjusting for confounders (p = 0.002). PC-3 accounted for 9.2% of the variance and shows positive loadings for cadmium, selenium, and PBDE congeners 47 and 153, and a negative loading for copper. Sensitivity analysis of the model to quantify likely effect sizes showed a range of menstrual cycle length from 25.3 to 28.3 days using the lower and upper 95% confidence limits of mean measured contaminant concentrations to predict cycle length. Our observations support the hypothesis that the menstrual cycle function of these women may be altered by exposure to POHs and elements from their environment. Copyright © 2015. Published by Elsevier Ltd.

1. BUILDING 283, SOUTH SIDE OF CA.19471950 ADDITION (ONEANDONEHALFSTORY, GABLEROOFED ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. BUILDING 283, SOUTH SIDE OF CA.1947-1950 ADDITION (ONE-AND-ONE-HALF-STORY, GABLE-ROOFED STRUCTURE AND ONE-STORY, FLAT-ROOFED STRUCTURE) AND WEST SIDE OF CA. 1926 WAREHOUSE (TWO-STORY, GABLE-ROOFED STRUCTURE). - Presidio of San Francisco, Warehouse & Auto Shop, Crissy Field North cantonment, San Francisco, San Francisco County, CA

46 CFR 308.409 - Standard form of War Risk Builder's Risk Insurance Policy, Form MA-283.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 8 2011-10-01 2011-10-01 false Standard form of War Risk Builder's Risk Insurance Policy, Form MA-283. 308.409 Section 308.409 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Builder's Risk Insurance § 308.409 Standard form...

46 CFR 308.409 - Standard form of War Risk Builder's Risk Insurance Policy, Form MA-283.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 8 2013-10-01 2013-10-01 false Standard form of War Risk Builder's Risk Insurance Policy, Form MA-283. 308.409 Section 308.409 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Builder's Risk Insurance § 308.409 Standard form...

46 CFR 308.409 - Standard form of War Risk Builder's Risk Insurance Policy, Form MA-283.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Standard form of War Risk Builder's Risk Insurance Policy, Form MA-283. 308.409 Section 308.409 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Builder's Risk Insurance § 308.409 Standard form...

46 CFR 308.409 - Standard form of War Risk Builder's Risk Insurance Policy, Form MA-283.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 8 2012-10-01 2012-10-01 false Standard form of War Risk Builder's Risk Insurance Policy, Form MA-283. 308.409 Section 308.409 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Builder's Risk Insurance § 308.409 Standard form...

46 CFR 308.409 - Standard form of War Risk Builder's Risk Insurance Policy, Form MA-283.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 8 2014-10-01 2014-10-01 false Standard form of War Risk Builder's Risk Insurance Policy, Form MA-283. 308.409 Section 308.409 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Builder's Risk Insurance § 308.409 Standard form...

Fast Facts: Recent Statistics from the Library Research Service, Numbers 283-289. January-December, 2010

ERIC Educational Resources Information Center

Library Research Service, 2010

2010-01-01

Issues 283 through 289 of "Fast Facts" from the Library Research Service present data collected from libraries in Colorado and throughout the nation. Topics addressed in these "Fast Facts" from 2010 include the relationship between computer access in libraries and use of traditional services, analysis of the third year of data…

Evaluation of the Impact of Kerojet (trademark) Aquarius Water Scavenger Additive on the Thermal Stability of Jet A Fuels

DTIC Science & Technology

2014-12-01

113 Figure 64 - Elemental Analysis, Typical TMS Post - Test , Post Carbon Burn-off, Hexane rinsed ............ 114 Figure 65 – SEM (20X...Agency’s Wright-Patterson Aerospace Fuels Laboratory AFRL Air Force Research Laboratory AFTSTU Aviation Fuel Thermal Stability Test Unit ARSFSS Advanced...Approved for public release; distribution unlimited. For all ARSFSS testing , SV hysteresis is measure pre- and post - test and is defined by relating

The behavior and concentration of CO2 in the suboceanic mantle: Inferences from undegassed ocean ridge and ocean island basalts

NASA Astrophysics Data System (ADS)

Michael, Peter J.; Graham, David W.

2015-11-01

In order to better determine the behavior of CO2 relative to incompatible elements, and improve the accuracy of mantle CO2 concentration and flux estimates, we determined CO2 glass and vesicle concentrations, plus trace element contents for fifty-one ultradepleted mid-ocean ridge basalt (MORB) glasses from the global mid-ocean ridge system. Fifteen contained no vesicles and were volatile undersaturated for their depth of eruption. Thirty-six contained vesicles and/or were slightly oversaturated, and so may not have retained all of their CO2. If this latter group lost some bubbles during emplacement, then CO2/Ba calculated for the undersaturated group alone is the most reliable and uniform ratio at 98 ± 10, and CO2/Nb is 283 ± 32. If the oversaturated MORBs did not lose bubbles, then CO2/Nb is the most uniform ratio within the entire suite of ultradepleted MORBs at 291 ± 132, while CO2/Ba decreases with increasing incompatible element enrichment. Additional constraints on CO2/Ba and CO2/Nb ratios are provided by published estimates of CO2 contents in highly vesicular enriched basalts that may have retained their vesicles e.g., the Mid-Atlantic Ridge "popping rocks", and from olivine-hosted melt inclusions in normal MORBs. As incompatible element enrichment increases, CO2/Nb increases progressively from 283 ± 32 in ultradepleted MORBs to 603 ± 69 in depleted melt inclusions to 936 ± 132 in enriched, vesicular basalts. In contrast, CO2/Ba is nearly uniform in these sample suites at 98 ± 10, 106 ± 24 and 111 ± 11 respectively. This suggests that Ba is the best proxy for estimating CO2 contents of MORBs, with an overall average CO2/Ba = 105 ± 9. Atlantic, Pacific and Indian basalts have similar values. Gakkel Ridge has lower CO2/Ba because of anomalously high Ba, and is not included in our global averages. Using the CO2/Ba ratio and published compilations of trace elements in average MORBs, the CO2 concentration of a primary, average MORB is 2085+ 473/- 427 ppm, while primary NMORB magmas (> 500 km from ocean island hotspots) have 1840 ppm CO2. The annual flux of CO2 from mid-ocean ridges is 1.25 ± 0.16 × 1014 g/yr, with possible values as low as 0.93 and as high as 1.61 × 1014 g/yr. This amount is equivalent to approximately 0.3% of the anthropogenic addition of CO2 to Earth's atmosphere. NMORB mantle has 183 ppm CO2 (50 ppm C) based on simple melting models and 13% melting. More realistic estimates of incompatible element concentrations in the depleted mantle that are consistent with complex melting models yield much lower estimates for CO2 in the depleted mantle: around 60-130 ppm CO2, with large uncertainties that are more related to melting models than to CO2/Ba. CO2/Ba is not correlated with isotopic or trace element ratios, but there may be systematic regional mantle variations. Iceland melt inclusions and Gakkel Ridge MORBs have lower CO2/Ba ratios, showing that these regional high Ba anomalies are not accompanied by correspondingly high CO2 concentrations.

Long-Term Control of HIV-1 in Hemophiliacs Carrying Slow-Progressing Allele HLA-B*5101▿ †

PubMed Central

Kawashima, Yuka; Kuse, Nozomi; Gatanaga, Hiroyuki; Naruto, Takuya; Fujiwara, Mamoru; Dohki, Sachi; Akahoshi, Tomohiro; Maenaka, Katsumi; Goulder, Philip; Oka, Shinichi; Takiguchi, Masafumi

2010-01-01

HLA-B*51 alleles are reported to be associated with slow disease progression to AIDS, but the mechanism underlying this association is still unclear. In the present study, we analyzed the effect of HLA-B*5101 on clinical outcome for Japanese hemophiliacs who had been infected with HIV-1 before 1985 and had been recruited in 1998 for this study. HLA-B*5101+ hemophiliacs exhibited significantly slow progression. The analysis of HLA-B*5101-restricted HIV-1-specific cytotoxic T-lymphocyte (CTL) responses to 4 HLA-B*-restricted epitopes in 10 antiretroviral-therapy (ART)-free HLA-B*5101+ hemophiliacs showed that the frequency of Pol283-8-specific CD8+ T cells was inversely correlated with the viral load, whereas the frequencies of CD8+ T cells specific for 3 other epitopes were positively correlated with the viral load. The HLA-B*5101+ hemophiliacs whose HIV-1 replication had been controlled for approximately 25 years had HIV-1 possessing the wild-type Pol283-8 sequence or the Pol283-8V mutant, which does not critically affect T-cell recognition, whereas other HLA-B*5101+ hemophiliacs had HIV-1 with escape mutations in this epitope. The results suggest that the control of HIV-1 over approximately 25 years in HLA-B*5101-positive hemophiliacs is associated with a Pol283-8-specific CD8+ T-cell response and that lack of control of HIV-1 is associated with the appearance of Pol283-8-specific escape mutants. PMID:20410273

40 CFR 96.283 - Applying for CAIR opt-in permit.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS CAIR SO2 Opt-in Units § 96.283 Applying for CAIR opt-in permit. (a) Applying for initial CAIR opt-in permit. The CAIR designated representative of a unit meeting the requirements for a CAIR SO2 opt-in unit...

Hypervirulent Clone of Group B Streptococcus Serotype III Sequence Type 283, Hong Kong, 1993–2012

PubMed Central

Ang, Irene; Fung, Kitty; Liyanapathirana, Veranja; Luo, Ming Jing; Lai, Raymond

2016-01-01

We describe a hypervirulent clone of group B Streptococcus serotype III, subtype 4, sequence type 283, that caused invasive disease with a predilection for meningitis in Hong Kong during 1993–2012. The organism is associated with high mortality and increased summer prevalence and is linked to diseased fish from freshwater fish farms. PMID:27648702

75 FR 30270 - Airworthiness Directives; Turbomeca Astazou XIV B and XIV H Turboshaft Engines

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-01

... detail. SN 283 72 0805 provides instructions for re-boring the holes at overhaul or repair in order to... modification AB 173 by changing only the riveting detail. SB 283 72 0805 provides instructions for re-boring... provides instructions for re-boring the holes at overhaul or repair in order to improve their surface...

Thermophysical Properties of Matter - The TPRC Data Series. Volume 4. Specific Heat - Metallic Elements and Alloys

DTIC Science & Technology

1971-01-01

alloys— sodium — sodium alloya— solder—carbon ateels—chromium steels—silicon steels—tantalum—tantalum alloys—terbium—thallium—thallium alloys—thorium...Praseodymium 45 Rhenium 46 Rhodium 47 Rubidium 48 Ruthenium 4» Samarium 50 Scandium 51 Selenium 52 Silicon 5:i Silver 54 Sodium 55 Strontium 56...Potassium ♦ Sodium 111 Sodium * Potassium 112 Tantalum ♦ Tungsten 113 Thallium + Lead, PbTl| 114 Tin ♦ Bismuth 115 Tin ♦ Indium 116 Tin+ Lead 117

Minnesota Water Allocation Law. Volume 1. Commentary on and Abstracts of Treaties, Legislation and Rules.

DTIC Science & Technology

1987-09-01

If applicable) 8c. ADDRESS(City, State, and ZIP Code) 10. SOURCE OF FUNDING NUMBERS ELEMENT NO. NO. NO ACCESSION NO .T 11 TITLE (Include Security...Indians 1-13 Domestic Water Supply on Reservations 1-14 Ground water sources 1-16 Surface water sources 1-16 Commentary on Indian Water Resources 1-17...General’s Office - St. Paul, Minnesota 4 DATA COLLECTION AND REPORT ORGANIZATION Data collected for these volumes result from three primary sources

Effect of Outside Combustion Air on Gas Furnace Efficiency.

DTIC Science & Technology

1981-10-15

Support Agency REPORT FESA-TS-2104 EFFECT OF OUTSIDE COMBUSTION AIR ON GAS FURNACE EFFICIENCY THOMAS E. BRISBANE Q KATHLEEN L. HANCOCK u JOHNS - MANVILLE SALES...and Dilution Air With No Furnace Setback. 93 AO-A113 4~84 . JOHNS - MANVILLE SALES CORP DENVER CO RESEARCH AND OEV--ETC F/6 13/ 1 EFFECT OF OUTSIDE...NUMBER(S) Thomas E. Brisbane, Kathleen L. Hancock DAAK 70-78-D-0002 9. PERFORMING ORGANIZATION NAME AND ADDRESS 1O. PROGRAM ELEMENT. PR.;ECT, TASK Johns

Targeting homeostasis in drug delivery using bioresponsive hydrogel microforms.

PubMed

Wilson, A Nolan; Guiseppi-Elie, Anthony

2014-01-30

A drug delivery platform comprising a biocompatible, bioresponsive hydrogel and possessing a covalently tethered peptide-drug conjugate was engineered to achieve stasis, via a closed control loop, of the external biochemical activity of the actuating protease. The delivery platform contains a peptide-drug conjugate covalently tethered to the hydrogel matrix, which in the presence of the appropriate protease, was cleaved and the drug released into the bathing environment. This platform was developed and investigated in silico using a finite element modeling (FEM) approach. Firstly, the primary governing phenomena guiding drug release profiles were investigated, and it was confirmed that under transport-limited conditions, the diffusion of the enzyme within the hydrogel and the coupled enzyme kinetics accurately model the system and are in agreement with published results. Secondly, the FEM model was used to investigate the release of a competitive protease inhibitor, MAG283, via cleavage of Acetyl-Pro-Leu-Gly|Leu-MAG-283 by MMP9 in order to achieve targeted homeostasis of MMP-9 activity, such as in the pathophysiology of chronic wounds, via closed-loop feedback control. The key engineering parameters for the delivery device are the radii of the hydrogel microspheres and the concentration of the peptide-inhibitor conjugate. Homeostatic drug delivery, where the focus turns away from the drug release rate and turns toward achieving targeted control of biochemical activity within a biochemical pathway, is an emerging approach in drug delivery methodologies for which the potential has not yet been fully realized. Copyright © 2013 Elsevier B.V. All rights reserved.

STS-92 Mission Specialist Wakata gets ready to drive the M-113

NASA Technical Reports Server (NTRS)

2000-01-01

Getting ready to take his turn at the wheel of the M-113 is Mission Specialist Koichi Wakata of Japan. Behind him can be seen Mission Specialists Bill McArthur (left) and Leroy Chiao (right), who wait their turns. Learning to drive the armored vehicle is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

STS-92 Mission Specialist Wakata takes his turn driving the M-113

NASA Technical Reports Server (NTRS)

2000-01-01

With Capt. George Hoggard, trainer with the KSC Fire Department, riding on top, Mission Specialist Koichi Wakata of Japan practices driving the M-113, part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. Riding in the back (on the left) are other crew members, waiting their turn to drive. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

STS-92 Mission Specialist McArthur is ready to take his turn driving the M-113

NASA Technical Reports Server (NTRS)

2000-01-01

STS-92 Mission Specialist Bill McArthur gets ready to take his turn at driving the M-113, part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. Behind him (left) is Mission Specialist Jeff Wisoff, waiting his turn to drive along with other unidentified crew members. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

STS-92 Mission Specialist Wakata completes his turn driving the M-113

NASA Technical Reports Server (NTRS)

2000-01-01

STS-92 Mission Specialist Koichi Wakata of Japan signals a successful driving lesson on the M-113 he is in. Capt. George Hoggard, trainer with the KSC Fire Department, sits on top. Behind Wakata are Commander Brian Duffy (left) and Leroy Chiao (right), waiting their turns. The practice drive is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

Beta Regio - Phoebe Regio on Venus: Geologic mapping with the Magellan data

NASA Technical Reports Server (NTRS)

Nikishin, A. M.; Borozdin, V. K.; Bobina, N. N.; Burba, G. A.

1993-01-01

The geologic maps of C1-15N283 and C1-00N283 sheets were produced (preliminary versions) with Magellan SAR images. This work was undertaken as a part of Russia's contribution into C1 geologic mapping efforts. The scale of the original maps is 1:8,000,000, and the maps are reproduced here at a reduced size.

45 CFR 283.7 - How will we use these data on abortions to determine bonus eligibility?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false How will we use these data on abortions to... REWARD DECREASE IN ILLEGITIMACY RATIO § 283.7 How will we use these data on abortions to determine bonus... calculate the rate of abortions for calendar year 1995 and for the most recent year for which abortion data...

45 CFR 283.7 - How will we use these data on abortions to determine bonus eligibility?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 2 2014-10-01 2012-10-01 true How will we use these data on abortions to... REWARD DECREASE IN ILLEGITIMACY RATIO § 283.7 How will we use these data on abortions to determine bonus... calculate the rate of abortions for calendar year 1995 and for the most recent year for which abortion data...

45 CFR 283.7 - How will we use these data on abortions to determine bonus eligibility?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false How will we use these data on abortions to... REWARD DECREASE IN ILLEGITIMACY RATIO § 283.7 How will we use these data on abortions to determine bonus... calculate the rate of abortions for calendar year 1995 and for the most recent year for which abortion data...

45 CFR 283.7 - How will we use these data on abortions to determine bonus eligibility?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 2 2012-10-01 2012-10-01 false How will we use these data on abortions to... REWARD DECREASE IN ILLEGITIMACY RATIO § 283.7 How will we use these data on abortions to determine bonus... calculate the rate of abortions for calendar year 1995 and for the most recent year for which abortion data...

45 CFR 283.7 - How will we use these data on abortions to determine bonus eligibility?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true How will we use these data on abortions to... REWARD DECREASE IN ILLEGITIMACY RATIO § 283.7 How will we use these data on abortions to determine bonus... calculate the rate of abortions for calendar year 1995 and for the most recent year for which abortion data...

Tyrosine quenching of tryptophan phosphorescence in glyceraldehyde-3-phosphate dehydrogenase from Bacillus stearothermophilus.

PubMed Central

Strambini, G B; Gabellieri, E; Gonnelli, M; Rahuel-Clermont, S; Branlant, G

1998-01-01

Tyrosine is known to quench the phosphorescence of free tryptophan derivatives in solution, but the interaction between tryptophan residues in proteins and neighboring tyrosine side chains has not yet been demonstrated. This report examines the potential role of Y283 in quenching the phosphorescence emission of W310 of glyceraldehyde-3-phosphate dehydrogenase from Bacillus stearothermophilus by comparing the phosphorescence characteristics of the wild-type enzyme to that of appositely designed mutants in which either the second tryptophan residue, W84, is replaced with phenylalanine or Y283 is replaced by valine. Phosphorescence spectra and lifetimes in polyol/buffer low-temperature glasses demonstrate that W310, in both wild-type and W84F (Trp84-->Phe) mutant proteins, is already quenched in viscous low-temperature solutions, before the onset of major structural fluctuations in the macromolecule, an anomalous quenching that is abolished with the mutation Y283V (Tyr283-->Val). In buffer at ambient temperature, the effect of replacing Y283 with valine on the phosphorescence of W310 is to lengthen its lifetime from 50 micros to 2.5 ms, a 50-fold enhancement that again emphasizes how W310 emission is dominated by the local interaction with Y283. Tyr quenching of W310 exhibits a strong temperature dependence, with a rate constant kq = 0.1 s(-1) at 140 K and 2 x 10(4) s(-1) at 293 K. Comparison between thermal quenching profiles of the W84F mutant in solution and in the dry state, where protein flexibility is drastically reduced, shows that the activation energy of the quenching reaction is rather small, Ea < or = 0.17 kcal mol(-1), and that, on the contrary, structural fluctuations play an important role on the effectiveness of Tyr quenching. Various putative quenching mechanisms are examined, and the conclusion, based on the present results as well as on the phosphorescence characteristics of other protein systems, is that Tyr quenching occurs through the formation of an excited-state triplet exciplex. PMID:9635769

Characterizing suspended sediments from the Piracicaba River Basin by means of k0-INAA

NASA Astrophysics Data System (ADS)

França, E. J.; Fernandes, E. A. N.; Cavalca, I. P. O.; Fonseca, F. Y.; Camilli, L.; Rodrigues, V. S.; Bardini Junior, C.; Ferreira, J. R.; Bacchi, M. A.

2010-10-01

The inorganic chemical characterization of suspended sediments is of utmost relevance for the knowledge of the dynamics and movement of chemical elements in the aquatic and wet ecosystems. Despite the complexity of the effective design for studying this ecological compartment, this work has tested a procedure for analyzing suspended sediments by instrumental neutron activation analysis, k0 method ( k0-INAA). The chemical elements As, Ba, Br, Ca, Ce, Co, Cr, Cs, Eu, Fe, Hf, Hg, K, La, Mo, Na, Ni, Rb, Sb, Sc, Se, Sm, Sr, Ta, Tb, Th, Yb and Zn were quantified in the suspended sediment compartment by means of k0-INAA. When compared with World Average for rivers, high mass fractions of Fe (222,900 mg/kg), Ba (4990 mg/kg), Zn (1350 mg/kg), Cr (646 mg/kg), Co (74.5 mg/kg), Br (113 mg/kg) and Mo (31.9 mg/kg) were quantified in suspended sediments from the Piracicaba River, the Piracicamirim Stream and the Marins Stream. Results of the principal component analysis for standardized chemical element mass fractions indicated an intricate correlation among chemical elements evaluated, as a response of the contribution of natural and anthropogenic sources of chemical elements for ecosystems.

Structural characterization of a novel full-length transcript promoter from Horseradish Latent Virus (HRLV) and its transcriptional regulation by multiple stress responsive transcription factors.

PubMed

Khan, Ahamed; Shrestha, Ankita; Bhuyan, Kashyap; Maiti, Indu B; Dey, Nrisingha

2018-01-01

The promoter fragment described in this study can be employed for strong transgene expression under both biotic and abiotic stress conditions. Plant-infecting Caulimoviruses have evolved multiple regulatory mechanisms to address various environmental stimuli during the course of evolution. One such mechanism involves the retention of discrete stress responsive cis-elements which are required for their survival and host-specificity. Here we describe the characterization of a novel Caulimoviral promoter isolated from Horseradish Latent Virus (HRLV) and its regulation by multiple stress responsive Transcription factors (TFs) namely DREB1, AREB1 and TGA1a. The activity of full length transcript (Flt-) promoter from HRLV (- 677 to + 283) was investigated in both transient and transgenic assays where we identified H12 (- 427 to + 73) as the highest expressing fragment having ~ 2.5-fold stronger activity than the CaMV35S promoter. The H12 promoter was highly active and near-constitutive in the vegetative and reproductive parts of both Tobacco and Arabidopsis transgenic plants. Interestingly, H12 contains a distinct cluster of cis-elements like dehydration-responsive element (DRE-core; GCCGAC), an ABA-responsive element (ABRE; ACGTGTC) and as-1 element (TGACG) which are known to be induced by cold, drought and pathogen/SA respectively. The specific binding of DREB1, AREB1 and TGA1a to DRE, ABRE and as-1 elements respectively were confirmed by the gel-binding assays using H12 promoter-specific probes. Detailed mutational analysis of the H12 promoter suggested that the presence of DRE-core and as-1 element was indispensable for its activity which was further confirmed by the transactivation assays. Our studies imply that H12 could be a valuable genetic tool for regulated transgene expression under diverse environmental conditions.

Radiographic changes of the distal phalangeal tuft of the hands in subjects with systemic sclerosis. Systematic review.

PubMed

Izquierdo, Yojhan Edilberto; Calvo Páramo, Enrique; Castañeda, Luisa María; Gómez, Sandra Viviana; Zambrano, Fernán Santiago

To determine abnormal plain radiograph findings of the distal phalanx tuft of the hand (DPTH) associated with systemic sclerosis in adults. A systematic review was developed following the parameters of the PRISMA guidelines in databases: MEDLINE, EMBASE, BIREME, Scielo, Google Scholar and others including as primary outcomes alterations of DPTH (erosions, resorption, sclerosis and proliferation) detected by simple radiography in subjects with systemic sclerosis. The prevalence of radiographic findings was synthesized using the fixed effects model. The statistical associations were expressed in terms of relative risk or odds ratio with their respective confidence intervals and p values. Twenty-two observational studies were included; the prevalence of DPTH resorption was 28.3% (95% CI: 0.256-0.312; p < .001); I 2 =80.4%, the prevalence of calcinosis was 15.6% (95% CI: 0.113-0.210; p < .001); I 2 =0%. No study reported proliferation or erosions and only one study described sclerosis of DPTH in 5 individuals. Resorption and calcinosis of DPTH are the characteristic radiographic findings in patients with systemic sclerosis. However, new studies with greater methodological strength are needed to establish associations between these phenomena and their presence in other connective tissue diseases. Copyright © 2016 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología. All rights reserved.

Triclosan causes spontaneous abortion accompanied by decline of estrogen sulfotransferase activity in humans and mice.

PubMed

Wang, Xiaoli; Chen, Xiaojiao; Feng, Xuejiao; Chang, Fei; Chen, Minjian; Xia, Yankai; Chen, Ling

2015-12-15

Triclosan (TCS), an antibacterial agent, is identified in serum and urine of humans. Here, we show that the level of urinary TCS in 28.3% patients who had spontaneous abortion in mid-gestation were increased by 11.3-fold (high-TCS) compared with normal pregnancies. Oral administration of TCS (10 mg/kg/day) in mice (TCS mice) caused an equivalent urinary TCS level as those in the high-TCS abortion patients. The TCS-exposure from gestation day (GD) 5.5 caused dose-dependently fetal death during GD12.5-16.5 with decline of live fetal weight. GD15.5 TCS mice appeared placental thrombus and tissue necrosis with enhancement of platelet aggregation. The levels of placenta and plasma estrogen sulfotransferase (EST) mRNA and protein in TCS mice or high-TCS abortion patients were not altered, but their EST activities were significantly reduced compared to controls. Although the levels of serum estrogen (E2) in TCS mice and high-TCS abortion patients had no difference from controls, their ratio of sulfo-conjugated E2 and unconjugated E2 was reduced. The estrogen receptor antagonist ICI-182,780 prevented the enhanced platelet aggregation and placental thrombosis and attenuated the fetal death in TCS mice. The findings indicate that TCS-exposure might cause spontaneous abortion probably through inhibition of EST activity to produce placental thrombosis.

Triclosan causes spontaneous abortion accompanied by decline of estrogen sulfotransferase activity in humans and mice

PubMed Central

Wang, Xiaoli; Chen, Xiaojiao; Feng, Xuejiao; Chang, Fei; Chen, Minjian; Xia, Yankai; Chen, Ling

2015-01-01

Triclosan (TCS), an antibacterial agent, is identified in serum and urine of humans. Here, we show that the level of urinary TCS in 28.3% patients who had spontaneous abortion in mid-gestation were increased by 11.3-fold (high-TCS) compared with normal pregnancies. Oral administration of TCS (10 mg/kg/day) in mice (TCS mice) caused an equivalent urinary TCS level as those in the high-TCS abortion patients. The TCS-exposure from gestation day (GD) 5.5 caused dose-dependently fetal death during GD12.5–16.5 with decline of live fetal weight. GD15.5 TCS mice appeared placental thrombus and tissue necrosis with enhancement of platelet aggregation. The levels of placenta and plasma estrogen sulfotransferase (EST) mRNA and protein in TCS mice or high-TCS abortion patients were not altered, but their EST activities were significantly reduced compared to controls. Although the levels of serum estrogen (E2) in TCS mice and high-TCS abortion patients had no difference from controls, their ratio of sulfo-conjugated E2 and unconjugated E2 was reduced. The estrogen receptor antagonist ICI-182,780 prevented the enhanced platelet aggregation and placental thrombosis and attenuated the fetal death in TCS mice. The findings indicate that TCS-exposure might cause spontaneous abortion probably through inhibition of EST activity to produce placental thrombosis. PMID:26666354

Group B Streptococcus Infections Caused by Improper Sourcing and Handling of Fish for Raw Consumption, Singapore, 2015-2016.

PubMed

Chau, Man L; Chen, Swaine L; Yap, Min; Hartantyo, Sri H P; Chiew, Paul K T; Fernandez, Charlene J; Wong, Wai K; Fong, Rockey K; Tan, Wei L; Tan, Brian Z Y; Ng, Youming; Aung, Kyaw T; Mehershahi, Kurosh S; Goh, Christopher; Kang, Joanne S L; Barkham, Timothy; Leong, Adeline O K; Gutiérrez, Ramona A; Ng, Lee C

2017-12-01

We assessed microbial safety and quality of raw fish sold in Singapore during 2015-2016 to complement epidemiologic findings for an outbreak of infection with group B Streptococcus serotype III sequence type (ST) 283 associated with raw fish consumption. Fish-associated group B Streptococcus ST283 strains included strains nearly identical (0-2 single-nucleotide polymorphisms) with the human outbreak strain, as well as strains in another distinct ST283 clade (57-71 single-nucleotide polymorphisms). Our investigations highlight the risk for contamination of freshwater fish (which are handled and distributed separately from saltwater fish sold as sashimi) and the need for improved hygienic handling of all fish for raw consumption. These results have led to updated policy and guidelines regarding the sale of ready-to-eat raw fish dishes in Singapore.

Responses of trace elements to aerobic maximal exercise in elite sportsmen.

PubMed

Otag, Aynur; Hazar, Muhsin; Otag, Ilhan; Gürkan, Alper Cenk; Okan, Ilyas

2014-02-21

Trace elements are chemical elements needed in minute quantities for the proper growth, development, and physiology of the organism. In biochemistry, a trace element is also referred to as a micronutrient. Trace elements, such as nickel, cadmium, aluminum, silver, chromium, molybdenum, germanium, tin, titanium, tungsten, scandium, are found naturally in the environment and human exposure derives from a variety of sources, including air, drinking water and food. The Purpose of this study was investigated the effect of aerobic maximal intensity endurance exercise on serum trace elements as well-trained individuals of 28 wrestlers (age (year) 19.64±1.13, weight (Kg) 70.07 ± 15.69, height (cm) 176.97 ± 6.69) during and after a 2000 meter Ergometer test protocol was used to perform aerobic (75 %) maximal endurance exercise. Trace element serum levels were analyzed from blood samples taken before, immediately after and one hour after the exercise. While an increase was detected in Chromium (Cr), Nickel (Ni), Molybdenum (Mo) and Titanium (Ti) serum levels immediately after the exercise, a decrease was detected in Aluminum (Al), Scandium (Sc) and Tungsten (W) serum levels. Except for aluminum, the trace elements we worked on showed statistically meaningful responses (P < 0.05 and P < 0.001). According to the responses of trace elements to the exercise showed us the selection and application of the convenient sport is important not only in terms of sportsman performance but also in terms of future healthy life plans and clinically.

THERMAL DECOMPOSITION OF PEROXYACETYL NITRATE AND REACTIONS OF ACETYL PEROXY RADICALS WITH NO AND NO2 OVER THE TEMPERATURE RANGE 283-313K

EPA Science Inventory

The thermal decomposition of peroxyacetyl nitrate (PAN) in NO-NO2-air (or N2) mixtures has been studied at 740 torr total pressure over the temperature range 283-313 K. he experimental data obtained yield a rate constant for the thermal decomposition of PAN of k3 = 2.52 x 1016 e-...

A single genetic locus in the phytopathogen Pantoea stewartii enables gut colonization and pathogenicity in an insect host.

PubMed

Stavrinides, John; No, Alexander; Ochman, Howard

2010-01-01

Aphids are typically exposed to a variety of epiphytic and phytopathogenic bacteria, many of which have entomopathogenic potential. Here we describe the interaction between Pantoea stewartii ssp. stewartii DC283 (DC283), an enteric phytopathogen and causal agent of Stewart's wilt, and the pea aphid, Acyrthosiphon pisum. When ingested by aphids, DC283 establishes and aggregates in the crop and gut, preventing honeydew flow and excretion, resulting in aphid death in 72 h. A mutagenesis screen identified a single locus, termed ucp1 (youcannot pass), whose disruption abolishes aphid pathogenicity. Moreover, the expression of ucp1 in Escherichia coli is sufficient to mediate the hindgut aggregation phenotype by this normally avirulent species. Ucp1 is related to six other proteins in the DC283 genome, each having a common N-terminal region and a divergent C-terminus, but only ucp1 has a role in pathogenicity. Based on predicted motifs and secondary structure, Ucp1 is a membrane-bound protein that functions in bacterial adhesion and promotes the formation of aggregates that are lethal to the insect host. These results illustrate that the enteric plant pathogenic bacteria have the capacity to exploit alternative non-plant hosts, and retain genetic determinants for colonizing the gut.

Levels of Essential Elements in Different Medicinal Plants Determined by Using Inductively Coupled Plasma Mass Spectrometry

PubMed Central

2018-01-01

The objective of this study was to investigate the content of essential elements in medicinal plants in the Kingdom of Saudi Arabia (KSA). Five different medical plants (mahareeb (Cymbopogon schoenanthus), sheeh (Artemisia vulgaris), harjal (Cynanchum argel delile), nabipoot (Equisetum arvense), and cafmariam (Vitex agnus-castus)) were collected from Madina city in the KSA. Five elements Fe, Mn, Zn, Cu, and Se were determined by using inductively coupled plasma mass spectrometry (ICP-MS). Fe levels were the highest and Se levels were the lowest in all plants. The range levels of all elements in all plants were as follows: Fe 193.4–1757.9, Mn 23.6–143.7, Zn 15.4–32.7, Se 0.13–0.92, and Cu 11.3–21.8 µg/g. Intakes of essential elements from the medical plants in infusion were calculated: Fe 4.6–13.4, Mn 6.7–123.2, Zn 7.0–42.7, Se 0.14–1.5, and Cu 1.5–5.0 µg/dose. The calculated intakes of essential elements for all plants did not exceed the daily intake set by the World Health Organization (WHO) and European Food Safety Authority (EFSA). These medicinal plants may be useful sources of essential elements, which are vital for health. PMID:29744234

Metro Commuter Exposures to Particulate Air Pollution and PM2.5-Associated Elements in Three Canadian Cities: The Urban Transportation Exposure Study.

PubMed

Van Ryswyk, Keith; Anastasopolos, Angelos T; Evans, Greg; Sun, Liu; Sabaliauskas, Kelly; Kulka, Ryan; Wallace, Lance; Weichenthal, Scott

2017-05-16

System-representative commuter air pollution exposure data were collected for the metro systems of Toronto, Montreal, and Vancouver, Canada. Pollutants measured included PM 2.5 (PM = particulate matter), PM 10 , ultrafine particles, black carbon, and the elemental composition of PM 2.5 . Sampling over three weeks was conducted in summer and winter for each city and covered each system on a daily basis. Mixed-effect linear regression models were used to identify system features related to particulate exposures. Ambient levels of PM 2.5 and its elemental components were compared to those of the metro in each city. A microenvironmental exposure model was used to estimate the contribution of a 70 min metro commute to daily mean exposure to PM 2.5 elemental and mass concentrations. Time spent in the metro was estimated to contribute the majority of daily exposure to several metallic elements of PM 2.5 and 21.2%, 11.3% and 11.5% of daily PM 2.5 exposure in Toronto, Montreal, and Vancouver, respectively. Findings suggest that particle air pollutant levels in Canadian metros are substantially impacted by the systems themselves, are highly enriched in steel-based elements, and can contribute a large portion of PM 2.5 and its elemental components to a metro commuter's daily exposure.

Fine structure of the late Eocene Ir anomaly in marine sediments

NASA Technical Reports Server (NTRS)

Asaro, F.

1991-01-01

The Late Eocene Ir abundance profile in deep sea cores from Ocean Drilling Program Leg 113 Hole 689B on the Maude Rise off of Antarctica was studied with 410 samples continuously in 10 cm increments and measured with the Iridium Coincidence (ICS). The ICS was subsequently modified to measure 13 other elements simultaneously with the Ir. The abundance profiles of these elements were then determined in the Late Eocene Massignano section in central Italy with 250 samples (encompassing roughly 2 million years of accumulation) which were collected about every 5 cm in about 2 cm increments. These studies augmented a previous one (which included many elements) of deep sea cores from Deep Sea Drilling Project Site 592 on the Lord Howe Rise in the Tasman Sea between Australia and New Zealand. In the latter study, 50 samples (encompassing roughly 0.7 million years of accumulation) were collected continuously in 10 cm increments. The results from these studies are discussed.

Extended HSR/CARD domain mediates AIRE binding to DNA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maslovskaja, Julia, E-mail: julia.maslovskaja@ut.ee; Saare, Mario; Liiv, Ingrid

Autoimmune regulator (AIRE) activates the transcription of many genes in an unusual promiscuous and stochastic manner. The mechanism by which AIRE binds to the chromatin and DNA is not fully understood, and the regulatory elements that AIRE target genes possess are not delineated. In the current study, we demonstrate that AIRE activates the expression of transiently transfected luciferase reporters that lack defined promoter regions, as well as intron and poly(A) signal sequences. Our protein-DNA interaction experiments with mutated AIRE reveal that the intact homogeneously staining region/caspase recruitment domain (HSR/CARD) and amino acids R113 and K114 are key elements involved inmore » AIRE binding to DNA. - Highlights: • Promoter and mRNA processing elements are not important for AIRE to activate gene expression from reporter plasmids. • AIRE protein fragment aa 1–138 mediates direct binding to DNA. • Integrity of the HSR/CARD domain is needed for AIRE binding to DNA.« less

Basic distinctions between cold- and hot-fusion reactions in the synthesis of superheavy elements

NASA Astrophysics Data System (ADS)

Nasirov, A. K.; Muminov, A. I.; Giardina, G.; Mandaglio, G.

2014-07-01

Superheavy elements (SHE) of charge number in the range of Z = 106-112 were synthesized in so-called cold-fusion reactions. The smallness of the excitation energy of compound nuclei is the main advantage of cold-fusion reactions. However, the synthesis of SHEs of charge number in the region of Z ≥ 112 is strongly complicated in cold-fusion reactions by a sharp decrease in the cross section of a compound nucleus formation in the entrance channel because of superiority of quasifission in the competition with complete fusion. Two favorable circumstances contributed to the success of the experiments aimed at the synthesis of the Z = 113-118 elements and performed at the Laboratory of Nuclear Reactions at the Joint Institute for Nuclear Research: large cross sections for the production of a compound nucleus, which are characteristic of hot-fusion reactions, and an increase in the fission barrier for nuclei toward the stability island. The factor that complicates the formation of a compound nucleus in cold-fusion reactions is discussed.

Miniaturized force/torque sensor for in vivo measurements of tissue characteristics.

PubMed

Hessinger, M; Pilic, T; Werthschutzky, R; Pott, P P

2016-08-01

This paper presents the development of a surgical instrument to measure interaction forces/torques with organic tissue during operation. The focus is on the design progress of the sensor element, consisting of a spoke wheel deformation element with a diameter of 12 mm and eight inhomogeneous doped piezoresistive silicon strain gauges on an integrated full-bridge assembly with an edge length of 500 μm. The silicon chips are contacted to flex-circuits via flip chip and bonded on the substrate with a single component adhesive. A signal processing board with an 18 bit serial A/D converter is integrated into the sensor. The design concept of the handheld surgical sensor device consists of an instrument coupling, the six-axis sensor, a wireless communication interface and battery. The nominal force of the sensing element is 10 N and the nominal torque is 1 N-m in all spatial directions. A first characterization of the force sensor results in a maximal systematic error of 4.92 % and random error of 1.13 %.

Group B Streptococcus Infections Caused by Improper Sourcing and Handling of Fish for Raw Consumption, Singapore, 2015–2016

PubMed Central

Chau, Man L.; Chen, Swaine L.; Yap, Min; Hartantyo, Sri H.P.; Chiew, Paul K.T.; Fernandez, Charlene J.; Wong, Wai K.; Fong, Rockey K.; Tan, Wei L.; Tan, Brian Z.Y.; Ng, Youming; Aung, Kyaw T.; Mehershahi, Kurosh S.; Goh, Christopher; Kang, Joanne S.L.; Barkham, Timothy; Leong, Adeline O.K.; Gutiérrez, Ramona A.

2017-01-01

We assessed microbial safety and quality of raw fish sold in Singapore during 2015–2016 to complement epidemiologic findings for an outbreak of infection with group B Streptococcus serotype III sequence type (ST) 283 associated with raw fish consumption. Fish-associated group B Streptococcus ST283 strains included strains nearly identical (0–2 single-nucleotide polymorphisms) with the human outbreak strain, as well as strains in another distinct ST283 clade (57–71 single-nucleotide polymorphisms). Our investigations highlight the risk for contamination of freshwater fish (which are handled and distributed separately from saltwater fish sold as sashimi) and the need for improved hygienic handling of all fish for raw consumption. These results have led to updated policy and guidelines regarding the sale of ready-to-eat raw fish dishes in Singapore. PMID:29148967

Development of a Solid Rocket Propellant Nonlinear Constitutive Theory

DTIC Science & Technology

1975-05-01

14 21 29 15 28 27 45 34 44 28 43 22 16 41 lü 40 58 35 57 59 56 23 55 17 54 11 53 36 30 24 18 1? J 6 0.0 0.1 0.2 0.3...Analysis 123 SECTION 6 - TASK IV - FINITE ELEMENT CODE DEMONSTRATION 139 A. Work to be Accomplished 139 B. Original Task IV Effort 139 C. Task IV...Vlscoelastlc Predictions 55 and Fyperimental Data for Sollthane 113 6 Comparison of Linear Vlscoelastlc Predictions 56 and Experimental Data for

Biodegradation of DIMP, Dieldrin, Isodrin, DBCP, and PCPMSO in Rocky Mountain Arsenal Soils. Installation Restoration Program, Environmental Technology Development

DTIC Science & Technology

1989-01-01

Number DAAK- 1 1 -85-D-007 Report Number CETHA-TE-CR-89006 January 1989 Prepared for: COMMANDER, U.S. ARMY TOXIC AND HAZARDOUS MATERIALS AGENCY Aberdeen...UNIT Aberdeen Proving Ground, MD 21010-5401 ELEMENT NO. NO. NO. ACCESSION NO. 1 . TITLE (Include Security Classification) - Biodegradation of DIMP...TYPE OF REPORT 113b. TIME COVERED 114. DATE OF REPORT (Year, Month, Day) 15. PAGE COUNT Final I FROM 1 /87 TO_1/89 1989 January 30 6. SUPPLEMENTARY

GEODYN programmers guide, volume 2, part 1

NASA Technical Reports Server (NTRS)

Mullins, N. E.; Goad, C. C.; Dao, N. C.; Martin, T. V.; Boulware, N. L.; Chin, M. M.

1972-01-01

A guide to the GEODYN Program is presented. The program estimates orbit and geodetic parameters. It possesses the capability to estimate that set of orbital elements, station positions, measurement biases, and a set of force model parameters such that the orbital tracking data from multiple arcs of multiple satellites best fit the entire set of estimated parameters. GEODYN consists of 113 different program segments, including the main program, subroutines, functions, and block data routines. All are in G or H level FORTRAN and are currently operational on GSFC's IBM 360/95 and IBM 360/91.

Three-energy focusing Laue monochromator for the diamond light source x-ray pair distribution function beamline I15-1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sutter, John P., E-mail: john.sutter@diamond.ac.uk; Chater, Philip A.; Hillman, Michael R.

2016-07-27

The I15-1 beamline, the new side station to I15 at the Diamond Light Source, will be dedicated to the collection of atomic pair distribution function data. A Laue monochromator will be used consisting of three silicon crystals diffracting X-rays at a common Bragg angle of 2.83°. The crystals use the (1 1 1), (2 2 0), and (3 1 1) planes to select 40, 65, and 76 keV X-rays, respectively, and will be bent meridionally to horizontally focus the selected X-rays onto the sample. All crystals will be cut to the same optimized asymmetry angle in order to eliminate imagemore » broadening from the crystal thickness. Finite element calculations show that the thermal distortion of the crystals will affect the image size and bandpass.« less

9 CFR 113.113 - Autogenous biologics.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Autogenous biologics. 113.113 Section 113.113 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS...

Design selection of an innovative tool holder for ultrasonic vibration assisted turning (IN-UVAT) using finite element analysis simulation

NASA Astrophysics Data System (ADS)

Rachmat, Haris; Ibrahim, M. Rasidi; Hasan, Sulaiman bin

2017-04-01

On of high technology in machining is ultrasonic vibration assisted turning. The design of tool holder was a crucial step to make sure the tool holder is enough to handle all forces on turning process. Because of the direct experimental approach is expensive, the paper studied to predict feasibility of tool holder displacement and effective stress was used the computational in finite element simulation. SS201 and AISI 1045 materials were used with sharp and ramp corners flexure hinges on design. The result shows that AISI 1045 material and which has ramp corner flexure hinge was the best choice to be produced. The displacement is around 11.3 micron and effective stress is 1.71e+008 N/m2 and also the factor of safety is 3.10.

A RecA Protein Surface Required for Activation of DNA Polymerase V

PubMed Central

Gruber, Angela J.; Erdem, Aysen L.; Sabat, Grzegorz; Karata, Kiyonobu; Jaszczur, Malgorzata M.; Vo, Dan D.; Olsen, Tayla M.; Woodgate, Roger; Goodman, Myron F.; Cox, Michael M.

2015-01-01

DNA polymerase V (pol V) of Escherichia coli is a translesion DNA polymerase responsible for most of the mutagenesis observed during the SOS response. Pol V is activated by transfer of a RecA subunit from the 3'-proximal end of a RecA nucleoprotein filament to form a functional complex called DNA polymerase V Mutasome (pol V Mut). We identify a RecA surface, defined by residues 112-117, that either directly interacts with or is in very close proximity to amino acid residues on two distinct surfaces of the UmuC subunit of pol V. One of these surfaces is uniquely prominent in the active pol V Mut. Several conformational states are populated in the inactive and active complexes of RecA with pol V. The RecA D112R and RecA D112R N113R double mutant proteins exhibit successively reduced capacity for pol V activation. The double mutant RecA is specifically defective in the ATP binding step of the activation pathway. Unlike the classic non-mutable RecA S117F (recA1730), the RecA D112R N113R variant exhibits no defect in filament formation on DNA and promotes all other RecA activities efficiently. An important pol V activation surface of RecA protein is thus centered in a region encompassing amino acid residues 112, 113, and 117, a surface exposed at the 3'-proximal end of a RecA filament. The same RecA surface is not utilized in the RecA activation of the homologous and highly mutagenic RumA'2B polymerase encoded by the integrating-conjugative element (ICE) R391, indicating a lack of structural conservation between the two systems. The RecA D112R N113R protein represents a new separation of function mutant, proficient in all RecA functions except SOS mutagenesis. PMID:25811184

Three out of four disease-modifying anti-rheumatic drug-naïve rheumatoid arthritis patients meet 28-joint Disease Activity Score remission at 12 months: results from the FIN-ERA cohort.

PubMed

Rannio, T; Asikainen, J; Hannonen, P; Yli-Kerttula, T; Ekman, P; Pirilä, L; Kuusalo, L; Mali, M; Puurtinen-Vilkki, M; Kortelainen, S; Paltta, J; Taimen, K; Kauppi, M; Laiho, K; Nyrhinen, S; Mäkinen, H; Isomäki, P; Uotila, T; Aaltonen, K; Kautiainen, H; Sokka, T

2017-11-01

To assess what proportion of patients with disease-modifying anti-rheumatic drug (DMARD)-naïve early rheumatoid arthritis (ERA) reach 28-joint Disease Activity Score (DAS28) remission over 1 year, and remission variability across clinics in Finland. Patients with DMARD-naïve newly diagnosed inflammatory arthritis were recruited. The proportion of patients in 28-joint Disease Activity Score with three variables (DAS28-3) remission was compared across sites. Repeated measures were analysed using a mixed models approach with appropriate distribution and link function. In total, 611 patients were recruited at five sites: 67% were female; the mean (sd) age was 57 (16) years; 71% and 68% were positive for rheumatoid factor and anti-cyclic citrullinated peptides, respectively; and 23% had radiographic erosions. A total of 506 (83%) fulfilled the American College of Rheumatology/European League Against Rheumatism 2010 classification criteria for rheumatoid arthritis for further analyses. DAS28-3 remission was met by 68% and 75% at 3 and 12 months, respectively. The clinical site had no effect on remission when adjusted for confounders. At baseline, 68% used methotrexate-based combination therapy, and 31% used triple therapy with methotrexate, hydroxychloroquine, and sulphasalazine (the Fin-RACo regimen). In multivariate analysis, the only independent predictors of DAS28-3 remission at 12 months were lower baseline DAS28-3 and triple therapy as the initial treatment. Three out of four DMARD-naïve ERA patients in Finland are in remission during the first year from the diagnosis. High remission rates were achieved for most patients with the use of conventional synthetic DMARDs in combination. Treatment of DMARD-naïve ERA patients with the FIN-RACo regimen is a predictor of DAS28-3 remission in real-life rheumatology settings.

An Intercenter Comparison of Nasolabial Appearance Including a Center Using Nasoalveolar Molding.

PubMed

Peanchitlertkajorn, Supakit; Mercado, Ana; Daskalogiannakis, John; Hathaway, Ronald; Russell, Kathleen; Semb, Gunvor; Shaw, William; Lamichane, Manish; Cohen, Marilyn; Long, Ross E

2018-05-01

To compare nasolabial appearance outcomes of patients with complete unilateral cleft lip and palate (CUCLP) in preadolescence from 4 cleft centers including a center using nasoalveolar molding (NAM) and primary nasal reconstruction. Retrospective cohort study. Four cleft centers in North America. 135 subjects with repaired CUCLP. Frontal and profile facial pictures were assessed using the Asher-McDade rating scale. Intra- and interrater reliability were tested using weighted Kappa statistics. Median scores by center were compared with Kruskal-Wallis statistics. Intrarater reliability scores were moderate to good. Interrater reliability scores were moderate. Significant differences ( P < .05) among centers were found. For nasal form, center G (median = 2.83) had better scores than centers C and D (C median = 3.33, D median = 3.17). For nose symmetry, center G had better scores (median = 2.33) than all other centers (B median = 2.67, C median = 2.83, D median = 2.83). For vermillion border, center G had better scores (median = 2.58) than centers B and C (B median = 3.17, C median = 3.17). For nasolabial profile, center G (median score = 2.67) had better scores than center C (median = 3.00). For total nasolabial score, center G (median = 2.67) had better scores than all other centers (B median = 2.83, C median = 3, D median = 2.83). The protocol followed by center G, the only center that performed NAM and primary nasal reconstruction, produced better results in all categories when compared to center C, the only center that did not perform presurgical orthopedics or lip/nose revisions. When compared to centers that performed traditional presurgical orthopedics and surgical revisions (B and D), center G was not consistently better in all categories. As with other uncontrolled, retrospective intercenter studies, it is not possible to attribute the outcomes to a specific protocol component.

21 CFR 173.342 - Chlorofluorocarbon 113 and perfluorohexane.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Chlorofluorocarbon 113 and perfluorohexane. 173.342... HUMAN CONSUMPTION Specific Usage Additives § 173.342 Chlorofluorocarbon 113 and perfluorohexane. A..., also known as fluorocarbon 113, CFC 113 and FC 113) and 1 percent perfluorohexane (CAS Reg. No. 355-42...

13 CFR 113.310 - Recruitment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Recruitment. 113.310 Section 113... Discrimination on the Basis of Sex in Admission and Recruitment Prohibited § 113.310 Recruitment. (a) Nondiscriminatory recruitment. A recipient to which §§ 113.300 through 113.310 apply shall not discriminate on the...

Acquisition of a Spinning Disk Confocal Microscope to Enhance Research and Teaching Capabilities in the STEM Fields at Howard University

DTIC Science & Technology

2015-05-13

to view the dynamics of a fluorescently tagged Drosophila melanogaster protein (Fascin::GFP) in the female ovary during egg development. Students...Sod2n283. Notably among them is the Drosophila gene CG5873, which was upregulated ~40 fold in Sod2n283. CG5873 carries a highly conserved domain...increase in germline apoptosis. We are utilizing the CRISPR- Cas9 technology to generate genome -edited lines where green fluorescent protein (GFP

Maintenance Facilities for Ammunition, Explosives, and Toxics. Design Manual 28.3.

DTIC Science & Technology

1981-11-01

LOADING DOCK RAMP PROTECTION 28.3-2 8. FIRE PROTECTION 28.3-2 9. SECURITY 28.3-2 10. SAFETY 28.3-2 Section 2. GENERAL AMMUNITION MAINTENANCE SHOPS 28.3...protection in accordance with Section 3 1910.23c, Occupatioual Safety and Health Act Standards Manual. 5 8. FIRE PROTECTION. Fire protection for all...Volume 1, and Fire Protection Engineering, NAVFAC DM-8. 9. SECURITY. Maintenance facilities for ammunition, explosives, and I toxics shall be located so

Early Detection of Amyloid Plaque in Alzheimer’s Disease via X-Ray Phase CT

DTIC Science & Technology

2014-06-01

normal, pathologic and Alzheimer’s brains, in which the amyloid precursor protein (APP) will be included as a reference. Toward this goal, we have made...in x-ray flat panel imagers and the artifact removal using a wavelet -analysis-based algorithm” Med. Phys., 28(3): 812-25, 2001. 4. X Wu and H Liu...panel imagers and the artifact removal using a wavelet -analysis-based algorithm” Med. Phys., 28(3): 812-25, 2001 12. Tang X, Hsieh J, Nilsen RA

Early Detection of Amyloid Plaque in Alzheimer’s Disease via X-Ray Phase CT

DTIC Science & Technology

2013-06-01

fibrils in the x-ray phase contrast CT imaging, as a function over the molar concentrations corresponding to normal, pathologic and Alzheimer’s...panel imagers and the artifact removal using a wavelet -analysis-based algorithm” Med. Phys., 28(3): 812-25, 2001. 4. X Wu and H Liu, “Clinical...and the artifact removal using a wavelet -analysis-based algorithm” Med. Phys., 28(3): 812-25, 2001 12. Tang X, Hsieh J, Nilsen RA, Hagiwara A

Conserved Noncoding Elements in the Most Distant Genera of Cephalochordates: The Goldilocks Principle

PubMed Central

Yue, Jia-Xing; Kozmikova, Iryna; Ono, Hiroki; Nossa, Carlos W.; Kozmik, Zbynek; Putnam, Nicholas H.; Yu, Jr-Kai; Holland, Linda Z.

2016-01-01

Cephalochordates, the sister group of vertebrates + tunicates, are evolving particularly slowly. Therefore, genome comparisons between two congeners of Branchiostoma revealed so many conserved noncoding elements (CNEs), that it was not clear how many are functional regulatory elements. To more effectively identify CNEs with potential regulatory functions, we compared noncoding sequences of genomes of the most phylogenetically distant cephalochordate genera, Asymmetron and Branchiostoma, which diverged approximately 120–160 million years ago. We found 113,070 noncoding elements conserved between the two species, amounting to 3.3% of the genome. The genomic distribution, target gene ontology, and enriched motifs of these CNEs all suggest that many of them are probably cis-regulatory elements. More than 90% of previously verified amphioxus regulatory elements were re-captured in this study. A search of the cephalochordate CNEs around 50 developmental genes in several vertebrate genomes revealed eight CNEs conserved between cephalochordates and vertebrates, indicating sequence conservation over >500 million years of divergence. The function of five CNEs was tested in reporter assays in zebrafish, and one was also tested in amphioxus. All five CNEs proved to be tissue-specific enhancers. Taken together, these findings indicate that even though Branchiostoma and Asymmetron are distantly related, as they are evolving slowly, comparisons between them are likely optimal for identifying most of their tissue-specific cis-regulatory elements laying the foundation for functional characterizations and a better understanding of the evolution of developmental regulation in cephalochordates. PMID:27412606

21 CFR 173.342 - Chlorofluorocarbon 113 and perfluorohexane.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 3 2013-04-01 2013-04-01 false Chlorofluorocarbon 113 and perfluorohexane. 173... perfluorohexane. A mixture of 99 percent chlorofluorocarbon 113 (1,1,2-trichloro-1,2,2-trifluoroethane) (CAS Reg. No. 76-13-1, also known as fluorocarbon 113, CFC 113 and FC 113) and 1 percent perfluorohexane (CAS...

21 CFR 173.342 - Chlorofluorocarbon 113 and perfluorohexane.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 3 2012-04-01 2012-04-01 false Chlorofluorocarbon 113 and perfluorohexane. 173... perfluorohexane. A mixture of 99 percent chlorofluorocarbon 113 (1,1,2-trichloro-1,2,2-trifluoroethane) (CAS Reg. No. 76-13-1, also known as fluorocarbon 113, CFC 113 and FC 113) and 1 percent perfluorohexane (CAS...

21 CFR 173.342 - Chlorofluorocarbon 113 and perfluorohexane.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 3 2011-04-01 2011-04-01 false Chlorofluorocarbon 113 and perfluorohexane. 173... perfluorohexane. A mixture of 99 percent chlorofluorocarbon 113 (1,1,2-trichloro-1,2,2-trifluoroethane) (CAS Reg. No. 76-13-1, also known as fluorocarbon 113, CFC 113 and FC 113) and 1 percent perfluorohexane (CAS...

The generator coordinate Dirac-Fock method for open-shell atomic systems

NASA Astrophysics Data System (ADS)

Malli, Gulzari L.; Ishikawa, Yasuyuki

1998-11-01

Recently we developed generator coordinate Dirac-Fock and Dirac-Fock-Breit methods for closed-shell systems assuming finite nucleus and have reported Dirac-Fock and Dirac-Fock-Breit energies for the atoms He through Nobelium (Z=102) [see Refs. Reference 10Reference 11Reference 12Reference 13]. In this paper, we generalize our earlier work on closed-shell systems and develop a generator coordinate Dirac-Fock method for open-shell systems. We present results for a number of representative open-shell heavy atoms (with nuclear charge Z>80) including the actinide and superheavy transactinide (with Z>103) atomic systems: Fr (Z=87), Ac (Z=89), and Lr (Z=103) to E113 (eka-thallium, Z=113). The high accuracy obtained in our open-shell Dirac-Fock calculations is similar to that of our closed-shell calculations, and we attribute it to the fact that the representation of the relativistic dynamics of an electron in a spherical ball finite nucleus near the origin in terms of our universal Gaussian basis set is as accurate as that provided by the numerical finite difference method. The DF SCF energies calculated by Desclaux [At. Data. Nucl. Data Tables 12, 311 (1973)] (apart from a typographic error for Fr pointed out here) are higher than those reported here for atoms of some of the superheavy transactinide elements by as much as 5 hartrees (136 eV). We believe that this is due to the use by Desclaux of much larger atomic masses than the currently accepted values for these elements.

Elemental and Sr-Nd isotopic geochemistry of the Uradzhongqi magmatic complex in western Inner Mongolia, China: A record of early Permian post-collisional magmatism

NASA Astrophysics Data System (ADS)

Qiao, Xueyuan; Li, Wenbo; Zhong, Richen; Hu, Chuansheng; Zhu, Feng; Li, Zhihua

2017-08-01

The magmatic complex in Uradzhongqi, Inner Mongolia, is located in the western segment of the northern margin of the North China Craton (NCC). The dominant components in the complex include syenogranite, monzogranite, granodiorite, diorite and gabbro. Mafic microgranular enclaves (MMEs) are common in syenogranite and granodiorite. Zircon U-Pb dating shows that the ages of these rocks range from 283 to 270 Ma, suggesting an early Permian emplacement. The syenogranite and monzogranite are peraluminous I-type granites, exhibiting conspicuous negative Eu anomaly, enrichment in large-ion lithophile elements (LILE) and light rare earth elements (LREE), depletion in high field strength elements (HFSE). The granodiorites, diorites and MMEs are metaluminous in composition, show high Al2O3, MgO and Fe2O3T contents and weak negative Eu anomaly, as well as LREE and LILE enrichment and HFSE depletion. The gabbros show weak positive Eu anomaly and slight REE differentiation. The Sr-Nd isotope compositions show that the source of mafic magma was depleted mantle (DM) with possible involvement of enriched mantle II (EM II), whereas the felsic magma was derived from the Archean lower crust. Petrographic observation and analytical results of mineralogy, geochronology, geochemistry and Sr-Nd isotopes indicate that the main petrogenesis of these magmatic rocks is the mixing of underplating mafic magma and felsic magma. Tectonically, the complex pluton was formed within a post-collisional regime, and the underplating in this area provides another piece of evidence for the vertical growth of the western segment of the northern margin of the NCC.

9 CFR 113.8 - In vitro tests for serial release.

Code of Federal Regulations, 2013 CFR

2013-01-01

... REQUIREMENTS Applicability § 113.8 In vitro tests for serial release. (a) Master Seed which has been established as pure, safe, and immunogenic shall be used for preparing seed for production as specified in the...) Subjecting the master seed to the applicable requirements prescribed in §§ 113.64, 113.100, 113.200, and 113...

9 CFR 113.8 - In vitro tests for serial release.

Code of Federal Regulations, 2012 CFR

2012-01-01

... REQUIREMENTS Applicability § 113.8 In vitro tests for serial release. (a) Master Seed which has been established as pure, safe, and immunogenic shall be used for preparing seed for production as specified in the...) Subjecting the master seed to the applicable requirements prescribed in §§ 113.64, 113.100, 113.200, and 113...

9 CFR 113.8 - In vitro tests for serial release.

Code of Federal Regulations, 2014 CFR

2014-01-01

... REQUIREMENTS Applicability § 113.8 In vitro tests for serial release. (a) Master Seed which has been established as pure, safe, and immunogenic shall be used for preparing seed for production as specified in the...) Subjecting the master seed to the applicable requirements prescribed in §§ 113.64, 113.100, 113.200, and 113...

Surgical outcome of MRI-negative refractory extratemporal lobe epilepsy.

PubMed

Shi, Jianguo; Lacuey, Nuria; Lhatoo, Samden

2017-07-01

The aim of this study is to determine outcome of resective epilepsy surgery in MRI-negative extratemporal lobe epilepsy (MNETLE) patients who underwent invasive evaluations and to determine factors governing outcome. We studied 28 patients who underwent resective epilepsy surgery for MNETLE from August 2006 to November 2015, in whom complete follow-up information was available. Electro-clinical, pathological and surgical data were evaluated. 24 patients (82.8%) were explored with intracranial EEG (9 stereoelectroencephalography (SEEG), 7 subdural grids and 8 both). All patients were followed for at least 6 months. During a mean follow up period of 32 [6-113] months, 13 (46.4%) patients became seizure-free (ILAE 1) and 18 (64.3%) had a good (ILAE 1, 2, 3) outcome. 21 (75.0%) patients had focal cortical dysplasia (FCD). Univariate analysis showed that more restricted (regional) interictal and ictal epileptiform discharges in surface EEG were significantly associated with seizure freedom (P=0.016 and P=0.024). Multivariate analysis confirmed that having ≥120 electrode contacts in the evaluation is an independent variable predicting seizure freedom (HR=4.283, 95% CI=1.342-13.676, P=0.014). Invasive EEG is a powerful tool in the pre-surgical evaluation of patients with MNETLE. Invasive EEG implantation that include the irritative zone and EEG onset zone as indicated by surface EEG, as well as wider brain coverage predict seizure freedom, contingent upon a sound anatomo-electro-clinical hypothesis for implantation. Copyright © 2017 Elsevier B.V. All rights reserved.

Association Between Visceral Adiposity and Colorectal Polyps on CT Colonography

PubMed Central

Summers, Ronald M.; Liu, Jiamin; Sussman, Daniel L.; Dwyer, Andrew J.; Rehani, Bhavya; Pickhardt, Perry J.; Choi, J. Richard; Yao, Jianhua

2012-01-01

OBJECTIVE To determine if there is an association between visceral adiposity measured on CT colonography (CTC) and colorectal polyps. MATERIALS AND METHODS The study was HIPAA-compliant and approved by our Institutional Review Board and Office of Human Subjects Research. 1186 patients who underwent CTC and same day optical colonoscopy were analyzed. Visceral adipose tissue volumes (VAV) and volume percents relative to total internal body volume (VAV%) were measured on slices in the L2–L3 regions on supine CTC scan with validated fully-automated software. Student t-test, odds ratio (OR), logistic regression and receiver operating characteristic analyses were performed. RESULTS For subjects with and without adenomatous polyps, means and s. d. of VAV% were 31.2 ± 10.8% (n=345) and 28.2% ± 11.3% (n=841) (p<0.0001), respectively. For subjects with and without hyperplastic polyps they were 31.8% ± 10.7% (n=244) and 28.3% ± 11.2% (n=942) (p<0.0001), respectively. Comparing the lowest and highest quintiles of VAV%, the ORs for having at least one adenomatous polyp or hyperplastic polyp versus no polyp were 2.06 (95% CI: 1.36–3.13) and 1.71 [1.08, 2.71] and the prevalence of having adenomatous polyps or hyperplastic polyps increased 14% and 8%, respectively. CONCLUSION Subjects with higher visceral adiposity measurements on CTC have a greater risk for the presence of colonic polyps. PMID:22733893

Methamphetamine Use among Iranian Youth: A Population-based Knowledge, Attitude, and Practice study.

PubMed

Sharifi, Hamid; Shokoohi, Mostafa; Ahmad RafieiRad, Ali; Sargolzaie Moghadam, Maryam; Haghdoost, Ali-Akbar; Mirzazadeh, Ali; Karamouzian, Mohammad

2017-07-29

Despite the increasing prevalence of methamphetamine use among the young population in Iran, the body of literature on their methamphetamine use remains slim. This study was designed to investigate the knowledge, attitude, and practices of Iranian youth about methamphetamine to help inform harm reduction policies catered towards young men and women. In a cross-sectional study using multistage sampling in 13 provinces, 4868 participants aged 15-29 years old were recruited. Knowledge, attitude and practices of youth about methamphetamine were assessed through a pilot-tested interviewer-administered questionnaire. Descriptive statistics were presented and potential associations were assessed using Chi-square test and independent samples t-test. Mean age ±SD of the participants was 21.8 ± 5.6 years, and 49.5% were women. Overall, 21.7% and 37.7% of the participants had high knowledge scores and positive attitudes, respectively. Among the 19-29 years old participants, ever methamphetamine use and injection was estimated at 5.74% (95% CI: 4.21, 7.90) and 1.8% (95% CI: 1.13, 2.83), respectively. Most (44.3%) had started methamphetamine use for fun and media (69.1%) was reported as their main source of information on methamphetamine use. Methamphetamine use is a concerning health problem among Iranian youth. Comprehensive multi-sectoral downstream and upstream interventions that involve educational settings, as well as media, are urgently needed to help reduce the burden of methamphetamine use among Iranian youth.

Evolution of multi-drug resistant HCV clones from pre-existing resistant-associated variants during direct-acting antiviral therapy determined by third-generation sequencing

NASA Astrophysics Data System (ADS)

Takeda, Haruhiko; Ueda, Yoshihide; Inuzuka, Tadashi; Yamashita, Yukitaka; Osaki, Yukio; Nasu, Akihiro; Umeda, Makoto; Takemura, Ryo; Seno, Hiroshi; Sekine, Akihiro; Marusawa, Hiroyuki

2017-03-01

Resistance-associated variant (RAV) is one of the most significant clinical challenges in treating HCV-infected patients with direct-acting antivirals (DAAs). We investigated the viral dynamics in patients receiving DAAs using third-generation sequencing technology. Among 283 patients with genotype-1b HCV receiving daclatasvir + asunaprevir (DCV/ASV), 32 (11.3%) failed to achieve sustained virological response (SVR). Conventional ultra-deep sequencing of HCV genome was performed in 104 patients (32 non-SVR, 72 SVR), and detected representative RAVs in all non-SVR patients at baseline, including Y93H in 28 (87.5%). Long contiguous sequences spanning NS3 to NS5A regions of each viral clone in 12 sera from 6 representative non-SVR patients were determined by third-generation sequencing, and showed the concurrent presence of several synonymous mutations linked to resistance-associated substitutions in a subpopulation of pre-existing RAVs and dominant isolates at treatment failure. Phylogenetic analyses revealed close genetic distances between pre-existing RAVs and dominant RAVs at treatment failure. In addition, multiple drug-resistant mutations developed on pre-existing RAVs after DCV/ASV in all non-SVR cases. In conclusion, multi-drug resistant viral clones at treatment failure certainly originated from a subpopulation of pre-existing RAVs in HCV-infected patients. Those RAVs were selected for and became dominant with the acquisition of multiple resistance-associated substitutions under DAA treatment pressure.

Lambert W function for applications in physics

NASA Astrophysics Data System (ADS)

Veberič, Darko

2012-12-01

The Lambert W(x) function and its possible applications in physics are presented. The actual numerical implementation in C++ consists of Halley's and Fritsch's iterations with initial approximations based on branch-point expansion, asymptotic series, rational fits, and continued-logarithm recursion. Program summaryProgram title: LambertW Catalogue identifier: AENC_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AENC_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU General Public License version 3 No. of lines in distributed program, including test data, etc.: 1335 No. of bytes in distributed program, including test data, etc.: 25 283 Distribution format: tar.gz Programming language: C++ (with suitable wrappers it can be called from C, Fortran etc.), the supplied command-line utility is suitable for other scripting languages like sh, csh, awk, perl etc. Computer: All systems with a C++ compiler. Operating system: All Unix flavors, Windows. It might work with others. RAM: Small memory footprint, less than 1 MB Classification: 1.1, 4.7, 11.3, 11.9. Nature of problem: Find fast and accurate numerical implementation for the Lambert W function. Solution method: Halley's and Fritsch's iterations with initial approximations based on branch-point expansion, asymptotic series, rational fits, and continued logarithm recursion. Additional comments: Distribution file contains the command-line utility lambert-w. Doxygen comments, included in the source files. Makefile. Running time: The tests provided take only a few seconds to run.

Staphylococcus epidermidis adherence to human amniotic membrane and to human, rabbit, and cat conjunctiva.

PubMed

John, Thomas; Allen, Sam; John, Andrea G; Lai, Cathy I; Carey, Roberta B

2003-06-01

To evaluate Staphylococcus epidermidis adherence to human amniotic membrane (HAM) and compare it with S epidermidis adherence to human, rabbit, and cat conjunctiva in vitro. Research laboratory, Loyola University Medical Center, Maywood, Illinois, USA. Commercially available HAM (N = 3) was used. Conjunctival specimens from humans, rabbits, and cats (n = 3 each) were processed similarly to HAM. The tissues were exposed to S epidermidis (3 x 10(8) colony-forming units per milliliter) for 0, 5, 30, and 90 minutes, rinsed in sterile saline, and processed for light, scanning (SEM), and transmission (TEM) electron microscopy. Scanning electron microscopy (x2000) was used to quantify adherent bacteria/mm(2) of tissue (SEM photographs = 144). The following mean levels (+/- SD) of adherent S epidermidis/mm(2) were found at 0, 5, 30, and 90 minutes: HAM, 3833 +/- 1570, 9060 +/- 2512, 15,431 +/- 10,752, and 30,315 +/- 14,803, respectively; human conjunctiva, 1493 +/- 672, 7218 +/- 3179, 17,273 +/- 7168, and 19,861 +/- 9624, respectively; rabbit conjunctiva, 3385 +/- 5074, 14,386 +/- 14,569, 15,283 +/- 13,679, and 20,113 +/- 24,016, respectively; and cat conjunctiva, 4032 +/- 2240, 12,345 +/- 3413, 8512 +/- 4032, and 19,214 +/- 5584, respectively. No statistically significant differences were found at any time point (P>.16). There was no statistically significant difference in the adherence of S epidermidis to HAM and to human, rabbit, and cat conjunctiva. Bacterial adherence to HAM may be clinically significant.

Dynamic asymmetry and the role of the conserved active-site thiol in rabbit muscle creatine kinase.

PubMed

Londergan, Casey H; Baskin, Rachel; Bischak, Connor G; Hoffman, Kevin W; Snead, David M; Reynoso, Christopher

2015-01-13

Symmetric and asymmetric crystal structures of the apo and transition state analogue forms, respectively, of the dimeric rabbit muscle creatine kinase have invoked an "induced fit" explanation for asymmetry between the two subunits and their active sites. However, previously reported thiol reactivity studies at the dual active-site cysteine 283 residues suggest a more latent asymmetry between the two subunits. The role of that highly conserved active-site cysteine has also not been clearly determined. In this work, the S-H vibrations of Cys283 were observed in the unmodified MM isoform enzyme via Raman scattering, and then one and both Cys283 residues in the same dimeric enzyme were modified to covalently attach a cyano group that reports on the active-site environment via its infrared CN stretching absorption band while maintaining the catalytic activity of the enzyme. Unmodified and Cys283-modified enzymes were investigated in the apo and transition state analogue forms of the enzyme. The narrow and invariant S-H vibrational bands report a homogeneous environment for the unmodified active-site cysteines, indicating that their thiols are hydrogen bonded to the same H-bond acceptor in the presence and absence of the substrate. The S-H peak persists at all physiologically relevant pH's, indicating that Cys283 is protonated at all pH's relevant to enzymatic activity. Molecular dynamics simulations identify the S-H hydrogen bond acceptor as a single, long-resident water molecule and suggest that the role of the conserved yet catalytically unnecessary thiol may be to dynamically rigidify that part of the active site through specific H-bonding to water. The asymmetric and broad CN stretching bands from the CN-modified Cys283 suggest an asymmetric structure in the apo form of the enzyme in which there is a dynamic exchange between spectral subpopulations associated with water-exposed and water-excluded probe environments. Molecular dynamics simulations indicate a homogeneous orientation of the SCN probe group in the active site and thus rule out a local conformational explanation at the residue level for the multipopulation CN stretching bands. The homogeneous simulated SCN orientation suggests strongly that a more global asymmetry between the two subunits is the cause of the CN probe's broad and asymmetric infrared line shape. Together, these spectral observations localized at the active-site cysteines indicate an intrinsic, dynamic asymmetry between the two subunits that exists already in the apo form of the dimeric creatine kinase enzyme, rather than being induced by the substrate. Biochemical and methodological consequences of these conclusions are considered.

Production and isolation of homologs of flerovium and element 115 at the Lawrence Livermore National Laboratory Center for Accelerator Mass Spectrometry

DOE PAGES

Despotopulos, John D.; Kmak, Kelly N.; Gharibyan, Narek; ...

2015-10-01

Here, new procedures have been developed to isolate no-carrier-added (NCA) radionuclides of the homologs and pseudo-homologs of flerovium (Hg, Sn) and element 115 (Sb), produced by 12–15 MeV proton irradiation of foil stacks with the tandem Van-de-Graaff accelerator at the Lawrence Livermore National Laboratory Center for Accelerator Mass Spectrometry (CAMS) facility. The separation of 113Sn from natIn foil was performed with anion-exchange chromatography from hydrochloric and nitric acid matrices. A cation-exchange chromatography method based on hydrochloric and mixed hydrochloric/hydroiodic acids was used to separate 124Sb from natSn foil. A procedure using Eichrom TEVA resin was developed to separate 197Hg frommore » Au foil. These results demonstrate the suitability of using the CAMS facility to produce NCA radioisotopes for studies of transactinide homologs.« less

Research of a Tram Headstock from Composite

NASA Astrophysics Data System (ADS)

Malkovsky, Zdenek; Kovandova, Hedvika

2014-08-01

The requirements for crashworthiness of railway vehicles are defined by the Railroad crashworthiness standard EN 15227. This standard is based on the findings of the characteristics of steel structures of front parts of railway vehicles. In the Czech Republic an extensive research was carried out within the project TIP FR-TI1/113 on application of composite sandwich structure elements in the design of the front cabins of a railway vehicle. The aim of the research work was to determine real possibilities of the composite sandwich structures for use in the construction of railway vehicles while considering the validity of the above-mentioned standard.

The effect of environmental initiatives on NASA specifications and standards activities

NASA Technical Reports Server (NTRS)

Griffin, Dennis; Webb, David; Cook, Beth

1995-01-01

The NASA Operational Environment Team (NOET) has conducted a survey of NASA centers specifications and standards that require the use of Ozone Depleting Substances (ODS's) (Chlorofluorocarbons (CFCs), Halons, and chlorinated solvents). The results of this survey are presented here, along with a pathfinder approach utilized at Marshall Space Flight Center (MSFC) to eliminate the use of ODS's in targeted specifications and standards. Presented here are the lessons learned from a pathfinder effort to replace CFC-113 in a significant MSFC specification for cleaning and cleanliness verification methods for oxygen, fuel and pneumatic service, including Shuttle propulsion elements.

Oxygen surface exchange kinetics and stability of (La,Sr) 2 CoO 4±δ/La 1-xSr xMO 3-δ (M = Co and Fe) hetero-interfaces at intermediate temperatures

DOE PAGES

Lee, Dongkyu; Lee, Yueh-Lin; Hong, Wesley T.; ...

2014-11-13

Heterostructured oxide interfaces created by decorating Ruddlesden-Popper phases (A2BO4) or perovskites on perovskites have shown not only pronounced cation segregation at the interface and in the A2BO4 structure but also much enhanced kinetics for oxygen electrocatalysis at elevated temperatures. In this study, we report and compare the time-dependent surface exchange kinetics and stability of (La 0.5Sr 0.5) 2CoO 4 -decorated (LSC 214) La 0.6Sr 0.4Co 0.2Fe 0.8O 3-δ (LSCF 113) and La 0.8Sr 0.2CoO 3-δ (LSC 113) thin films. While LSC 214 decoration on LSC 113 greatly reduced the degradation in the surface exchange kinetics as a function of timemore » relative to LSC 113, LSCF 113 with LSC 214 coverage showed comparable surface exchange kinetics and stability to LSCF 113. This difference can be explained by greater surface stability of LSCF 113 than LSC 113 under testing conditions, and that LSC 214 decoration on LSC 113 reduced the decomposition of LSC 113 to form secondary phases that impedes oxygen exchange kinetics, and thus resulted in enhanced stability. This hypothesis is supported by the observations that annealing at 550 °C led to the formation of Sr-rich secondary particles on LSC 113 while no such particles were observed on LSCF 113. Density functional theory (DFT) computation provides further support, which revealed greater capacity of surface Sr segregation for LSCF 113 having SrO termination than LSC 113 having (La 0.25Sr 0.75)O termination for the experimental conditions, and lower energy gain to move Sr from LSCF 113 into LSC 214 relative to the LSC 214-LSC 113 system.« less

Limitations of Current AHA Guidelines and Proposal of New Guidelines for the Preparticipation Examination of Athletes.

PubMed

Dunn, Tim P; Pickham, David; Aggarwal, Sonya; Saini, Divya; Kumar, Nikhil; Wheeler, Matthew T; Perez, Marco; Ashley, Euan; Froelicher, Victor F

2015-11-01

To examine the prevalence of athletes who screen positive with the preparticipation examination guidelines from the American Heart Association, the AHA 12-elements, in combination with 3 screening electrocardiogram (ECG) criteria. Observational cross-sectional study. Stanford University Sports Medicine Clinic. Total of 1596 participants, including 297 (167 male; mean age, 16.2 years) high school athletes, 1016 (541 male; mean age, 18.8 years) collegiate athletes, and 283 (mean age, 26.3 years) male professional athletes. Athletes were screened using the 8 personal and family history questions from the AHA 12-elements. Electrocardiograms were obtained for all participants and interpreted using Seattle criteria, Stanford criteria, and European Society of Cardiology (ESC) recommendations. Approximately one-quarter of all athletes (23.8%) had at least 1 positive response to the AHA personal and family history elements. High school and college athletes had similar rates of having at least 1 positive response (25.9% vs 27.4%), whereas professional athletes had a significantly lower rate of having at least 1 positive response (8.8%, P < 0.05). Females reported more episodes of unexplained syncope (11.4% vs 7.5%, P = 0.017) and excessive exertional dyspnea with exercise (11.1% vs 6.1%, P = 0.001) than males. High school athletes had more positive responses to the family history elements when compared with college athletes (P < 0.05). The percentage of athletes who had an abnormal ECG varied between Seattle criteria (6.0%), Stanford criteria (8.8%), and ESC recommendations (26.8%). Many athletes screen positive under current screening recommendations, and ECG results vary widely by interpretation criteria. In a patient population without any adverse cardiovascular events, the currently recommended AHA 12-elements have an unacceptably high rate of false positives. Newer screening guidelines are needed, with fewer false positives and evidence-based updates.

Air Force Civil Engineer, Volume 9, Number 2, Summer 2001

DTIC Science & Technology

2001-01-01

c. THIS PAGE unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 F R O M T H E T O P Are you ready for a Graduate Degree...Suite 1, Tyndall AFB, FL, 32403-5319, Telephone (850) 283-6242, DSN 523-6242, FAX (850) 283-6499, and e -mail: cemag@tyndall.af.mil. All submissions...ciently capture the most current publications and updates. Keeping training on track The COVER Train package includes an E -Tutor, which will be used by

Encapsulation of a [Dy(OH2)8](3+) cation: magneto-optical and theoretical studies of a caged, emissive SMM.

PubMed

Al Hareri, M; Gavey, E L; Regier, J; Ras Ali, Z; Carlos, L D; Ferreira, R A S; Pilkington, M

2016-10-15

The first supramolecular cage formed by three benzo-15-crown-5 macrocycles encapsulating a [Dy(OH2)8](3+) guest cation is reported, with the Dy(iii) centre exhibiting local pseudo square antiprismatic D4d symmetry. The anisotropy barrier extracted from ac susceptibility studies, emission spectroscopy and ab initio calculations reveals that the second excited state Kramers doublet plays a key role in the magnetization dynamics due to the Ising character and near coparallel nature of the ground and first excited Kramers doublets.

21 CFR 173.342 - Chlorofluorocarbon 113 and perfluorohexane.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 3 2014-04-01 2014-04-01 false Chlorofluorocarbon 113 and perfluorohexane. 173... Additives § 173.342 Chlorofluorocarbon 113 and perfluorohexane. A mixture of 99 percent chlorofluorocarbon... 113 and FC 113) and 1 percent perfluorohexane (CAS Reg. No. 355-42-0) may be safely used in accordance...

Metal characterization of white hawthorn organs and infusions.

PubMed

Juranović Cindrić, Iva; Zeiner, Michaela; Konanov, Darija Mihajlov; Stingeder, Gerhard

2015-02-18

Hawthorn is one of the most commonly used European and North American phytopharmaceuticals. Because there is no information on metals in seeds, and only rare data for leaves and flowers, the aim of the present study was elemental analysis of the white hawthorn (Crataegus monogyna) by inductively coupled plasma emission spectrometry (ICP-AES) or inductively coupled plasma mass spectrometry (ICP-MS) after digestion in a microwave-assisted system. The limits of detection are below 2 μg/g for ICP-AES and 0.5 μg/g for ICP-MS. Hawthorn leaves and flowers contain essential elements at concentrations (mean values, RSD 2-8%) in mg/g of Ca, 1-4; K, 4-5; Mg, 1-2; and Na, <0.2); and at μg/g levels of Ba, 1-10; Co, <0.16; Cr, <1.4; Cu, 0.6-7; Fe, 1-37; Li, <0.5; Mn, 1-13; Mo, <0.17; Ni, <0.6; Sr, 0.2-2; and Zn, 1-31. Toxic elements were found in low quantities: As (<0.04), Cd (0.04-0.1), and Pb (0.1-2). Up to 10% of the metals is extracted into the infusions. The analyzed plant parts and infusions contain essential elements justifying its use as a medicinal plant, whereas the low quantities of harmful elements will not pose any risk to humans when consumed.

21 CFR 113.5 - Current good manufacturing practice.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Current good manufacturing practice. 113.5 Section... CONTAINERS General Provisions § 113.5 Current good manufacturing practice. The criteria in §§ 113.10, 113.40..., methods, practices, and controls used by the commercial processor in the manufacture, processing, or...

Does the sagittal alignment of the cervical spine have an impact on disk degeneration? Minimum 10-year follow-up of asymptomatic volunteers

PubMed Central

Okada, Eijiro; Ichihara, Daisuke; Chiba, Kazuhiro; Toyama, Yoshiaki; Fujiwara, Hirokazu; Momoshima, Suketaka; Nishiwaki, Yuji; Hashimoto, Takeshi; Ogawa, Jun; Watanabe, Masahiko; Takahata, Takeshi

2009-01-01

There have been few studies that investigated and clarified the relationships between progression of degenerative changes and sagittal alignment of the cervical spine. The objective of the study was to longitudinally evaluate the relationships among progression of degenerative changes of the cervical spine with age, the development of clinical symptoms and sagittal alignment of the cervical spine in healthy subjects. Out of 497 symptom-free volunteers who underwent MRI and plain radiography of the cervical spine between 1994 and 1996, 113 subjects (45 males and 68 females) who responded to our contacts were enrolled. All subjects underwent another MRI at an average of 11.3 years after the initial study. Their mean age at the time of the initial imaging was 36.6 ± 14.5 years (11–65 years). The items evaluated on MRI were (1) decrease in signal intensity of the intervertebral disks, (2) posterior disk protrusion, and (3) disk space narrowing. Each item was evaluated using a numerical grading system. The subjects were divided into four groups according to the age and sagittal alignment of the cervical spine, i.e., subjects under or over the age of 40 years, and subjects with the lordosis or non-lordosis type of sagittal alignment of the cervical spine. During the 10-year period, progression of decrease in signal intensity of the disk, posterior disk protrusion, and disk space narrowing were recognized in 64.6, 65.5, and 28.3% of the subjects, respectively. Progression of posterior disk protrusion was significantly more frequent in subjects over 40 years of age with non-lordosis type of sagittal alignment. Logistic regression analysis revealed that stiff shoulder was closely correlated with females (P = 0.001), and that numbness of the upper extremity was closely correlated with age (P = 0.030) and male (P = 0.038). However, no significant correlation between the sagittal alignment of the cervical spine and clinical symptoms was detected. Sagittal alignment of the cervical spine had some impact on the progression of degenerative changes of the cervical spine with aging; however, it had no correlation with the occurrence of future clinical symptoms. PMID:19609784

Competition by Bradyrhizobium Strains for Nodulation of the Nonlegume Parasponia andersonii

PubMed Central

Trinick, M. J.; Hadobas, P. A.

1989-01-01

Bradyrhizobium strains isolated from the nonlegume Parasponia spp. formed a group of strains that were highly competitive for nodulation of P. andersonii when paired with strains isolated from legumes. Strains from legumes, including those of similar effectiveness to NGR231 and CP283, were not able to form nodules as single occupants on P. andersonii in the presence of Parasponia strains. However, NGR86, an isolate from Macroptilium lathyroides, jointly occupied one-third of the nodules formed with each of the three strains isolated from Parasponia spp. Time taken for nodules to appear may have influenced the outcome of competition, since CP283 and all isolates from legumes were slow to nodulate P. andersonii. Among the Parasponia strains, competitiveness for nodulation of P. andersonii was not associated with effectiveness of nitrogen fixation. The highly effective strain CP299 was a poor competitor when paired with the least effective strain NGR231. CP283 was the least competitive of the Parasponia strains but was still able to dominate nodules when paired with legume isolates. Dual occupancy was high, up to 67% when the inoculum contained CP299 and CP273. Both the Muc+ and Muc- types of CP283 form a symbiosis of similar effectiveness and were similarly competitive at high inoculation densities, but the Muc- form was more competitive at low inoculum densities. Both forms frequently occupied the same nodule. Bradyrhizobium strains isolated from Parasponia spp. may have specific genetic information that favor their ability to competitively and effectively infect plants in the genus Parasponia (Ulmaceae) outside the Leguminosae. PMID:16347913

Origin discrimination of defatted pork via trace elements profiling, stable isotope ratios analysis, and multivariate statistical techniques.

PubMed

Park, Yu Min; Lee, Cheong Mi; Hong, Joon Ho; Jamila, Nargis; Khan, Naeem; Jung, Jong-Hyun; Jung, Young-Chul; Kim, Kyong Su

2018-09-01

This study verified the origin of 346 defatted Korean and non-Korean pork samples via trace elements profiling, and C and N stable isotope ratios analysis. The analyzed elements were 6 Li, 7 Li, 10 B, 11 B, 51 V , 50 Cr, 52 Cr, 53 Cr, 55 Mn, 58 Ni, 60 Ni, 59 Co, 63 Cu, 65 Cu, 64 Zn, 66 Zn, 69 Ga, 71 Ga, 75 As, 82 Se, 84 Sr, 86 Sr, 87 Sr, 88 Sr, 85 Rb, 94 Mo, 95 Mo, 97 Mo, 107 Ag, 109 Ag, 110 Cd, 111 Cd, 113 Cd, 112 Cd, 114 Cd, 116 Cd, 133 Cs, 206 Pb, 207 Pb, and 208 Pb. Content (mg/kg) of 51 V (0.012), 50 Cr (0.882), 75 As (0.017), 85 Rb (57.7), and 87 Sr (46.3) were high in Korean pork samples whereas 6 Li, 7 Li, 59 Co, 55 Mn, 58 Ni, 84 Sr, 86 Sr, 88 Sr, 111 Cd, and 133 Cs were found higher in non-Korean samples. The results of discriminant analysis showed that the trace elements content and stable isotope ratios were significant for the discrimination of geographical origins with a perfect discrimination rate of 100%. Copyright © 2018 Elsevier Ltd. All rights reserved.

26 CFR 1.113-1 - Mustering-out payments for members of the Armed Forces.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Forces. 1.113-1 Section 1.113-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY....113-1 Mustering-out payments for members of the Armed Forces. For the purposes of the exclusion from gross income under section 113 of mustering-out payments with respect to service in the Armed Forces...

Investigation of activation cross sections of deuteron induced reactions on indium up to 40 MeV for production of a 113 Sn/113m In generator.

PubMed

Tárkányi, F; Hermanne, A; Király, B; Takács, S; Ditrói, F; Baba, M; Ignatyuk, A V

2011-01-01

(113)Sn (115.09 d) is the parent nuclide of the (113)Sn/(113m)In generator system. (113m)In (99.476 min) is used in diagnostic nuclear medicine and as an Auger-electron emitter is a candidate for internal radiotherapy. Excitation functions of the (nat)In(d,x) (113 mg)Sn, (116 m)In, (ind115m)In, (114m)In, (ind113m)In, (cum111)In, (115g)Cd,(111m)Cd reactions were measured up to 40 MeV for the first time. The experimental results were compared with the curves calculated with the ALICE-D and EMPIRE-D theoretical model codes and curves given in the EAF-2007 and TENDL-2009 databases. Thick target yields, impurity levels and specific activities for the optimal energy range were deduced and compared with the same parameters of other charged particle production routes of (113)Sn. Copyright © 2010 Elsevier Ltd. All rights reserved.

STS-92 crew get training on driving the M-113 armored vehicle

NASA Technical Reports Server (NTRS)

2000-01-01

As part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities, members of the STS-92 crew get instructions about the M-113 they are seated in at Launch Pad 39A. Seen on the left are Pilot Pam Melroy and Mission Specialists Leroy Chaio and Koichi Wakata of Japan In the middle, giving the instructions, is Capt. George Hoggard, trainer with the KSC Fire Department. At right are Commander Brian Duffy (leaning back) and Mission Specialist Michael Lopez-Alegria. The other crew members (not seen) are Mission Specialists Jeff Wisoff and Bill McArthur. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-92 is scheduled to launch Oct. 5 at 9:30 p.m. EDT on the fifth flight to the International Space Station. It will carry two elements of the Space Station, the Integrated Truss Structure Z1 and the third Pressurized Mating Adapter. The mission is also the 100th flight in the Shuttle program.

Hydrodynamic interactions in freely suspended liquid crystal films

NASA Astrophysics Data System (ADS)

Kuriabova, Tatiana; Powers, Thomas R.; Qi, Zhiyuan; Goldfain, Aaron; Park, Cheol Soo; Glaser, Matthew A.; Maclennan, Joseph E.; Clark, Noel A.

2016-11-01

Hydrodynamic interactions play an important role in biological processes in cellular membranes, a large separation of length scales often allowing such membranes to be treated as continuous, two-dimensional (2D) fluids. We study experimentally and theoretically the hydrodynamic interaction of pairs of inclusions in two-dimensional, fluid smectic liquid crystal films suspended in air. Such smectic membranes are ideal systems for performing controlled experiments as they are mechanically stable, of highly uniform structure, and have well-defined, variable thickness, enabling experimental investigation of the crossover from 2D to 3D hydrodynamics. Our theoretical model generalizes the Levine-MacKintosh theory of point-force response functions and uses a boundary-element approach to calculate the mobility matrix for inclusions of finite extent. We describe in detail the theoretical and computational approach previously outlined in Z. Qi et al., Phys. Rev. Lett. 113, 128304 (2014), 10.1103/PhysRevLett.113.128304 and extend the method to study the mutual mobilities of inclusions with asymmetric shapes. The model predicts well the observed mutual mobilities of pairs of circular inclusions in films and the self-mobility of a circular inclusion in the vicinity of a linear boundary.

13 CFR 113.535 - Effect of state or local law or other requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Effect of state or local law or other requirements. 113.535 Section 113.535 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION... obligation to comply with §§ 113.500 through 113.550 is not obviated or alleviated by the existence of any...

Carbapenemase-Producing Enterobacteriaceae in Yunnan Province, China.

PubMed

Rui, Zheng; Dehua, Liu; Hua, Niu; Yue, Feng; Yunmin, Xu; Jianhua, Li; Xueshan, Xia

2016-11-22

Among 144 carbapenem-resistant Enterobacteriaceae strains isolated from 4 hospitals in Yunnan province, 113 were identified as carbapenemase-producing Enterobacteriaceae (CPE). Bla KPC-2 (99/113, 87.6%) was the most common carbapenemase gene and Klebsiella pneumoniae (100/113, 88.5%) was the most common species. Bla NDM-1 (11/113, 9.7%), bla IMP-4 (10/113, 8.8%), and bla IMP-1 (1/113, 0.9%) genes were also detected. Extended-spectrum β-lactamase genes were common in CPE, and the SHV- and CTX-M-types were predominant.

7 CFR 1956.113-1956.117 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 14 2010-01-01 2009-01-01 true [Reserved] 1956.113-1956.117 Section 1956.113-1956.117...) PROGRAM REGULATIONS (CONTINUED) DEBT SETTLEMENT Debt Settlement-Community and Business Programs §§ 1956.113-1956.117 [Reserved] ...

48 CFR 32.113 - Customary contract financing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... financing. 32.113 Section 32.113 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Non-Commercial Item Purchase Financing 32.113 Customary contract financing. The solicitation must specify the customary contract financing offerors may...

Measurement of excitation functions and analysis of isomeric population in some reactions induced by proton on natural indium at low energy

NASA Astrophysics Data System (ADS)

Muhammed Shan, P. T.; Musthafa, M. M.; Najmunnisa, T.; Mohamed Aslam, P.; Rajesh, K. K.; Hajara, K.; Surendran, P.; Nair, J. P.; Shanbagh, Anil; Ghugre, S.

2018-06-01

The excitation functions for reaction residues populated via 115In(p , p) 115 mIn, 115In(p , pn) 114 mIn, 115In(p , p 2 n) 113 mIn, 113In(p , p) 113 mIn, 115In(p , nα) 111 mCd, 115In(p , 3 n) 113Sn and 113In(p , n) 113Sn channels were measured over the proton energy range of 8-22 MeV using stacked foil activation technique. Theoretical analysis of the data were performed within the framework of two statistical model codes EMPIRE-3.2 and TALYS-1.8. Isomeric cross section ratio for isomeric pairs m,g 115In, m,g 114In, m,g 113In, 113Sn m,g and m,g 111Cd were determined for the first time. The dependence of isomeric cross section ratio on various factors are analysed.

East Europe Report: Economic and Industrial Affairs

DTIC Science & Technology

1985-04-04

Losses Due to Power Cuts (RUDE PRAVO, PRAVDA, 21 Feb 85) .............................. 43 GERMAN DEMOCRATIC REPUBLIC Analysis of Factors Contributing to...PREGLED, 5 Mar 85) ................................ .110 Briefs Problems at Trepca 112 Fire in Urosevac Combine 112 Fire in Prizren Textile Plant 113...Possible Bankruptcies in Kosovo 113 Private Farm Planting 113 Trade With Iraq 113 Rail Agreement With Hungary, USSR 113 Kosovo Water System Delay 114 -b

Better Care Teams: A Stepwise Skill Reinforcement Model.

PubMed

Christopher, Beth-Anne; Grantner, Mary; Coke, Lola A; Wideman, Marilyn; Kwakwa, Francis

2016-06-01

The Building Healthy Urban Communities initiative presents a path for organizations partnering to improve patient outcomes with continuing education (CE) as a key component. Components of the CE initiative included traditional CE delivery formats with an essential element of adaptability and new methods, with rigorous evaluation over time that included evaluation prior to the course, immediately following the CE session, 6 to 8 weeks after the CE session, and then subsequent monthly "testlets." Outcome measures were designed to allow for ongoing adaptation of content, reinforcement of key learning objectives, and use of innovative concordant testing and retrieval practice techniques. The results after 1 year of programming suggest the stepwise skill reinforcement model is effective for learning and is an efficient use of financial and human resources. More important, its design is one that could be adopted at low cost by organizations willing to work in close partnership. J Contin Educ Nurs. 2016;47(6):283-288. Copyright 2016, SLACK Incorporated.

Structural and magnetic characterizations of Co2FeGa/SiO2 nanoparticles prepared via chemical route

NASA Astrophysics Data System (ADS)

Priyanka, Dhaka, Rajendra S.

2018-04-01

We report the synthesis of Co2FeGa/SiO2 nanoparticles by sol-gel method and characterization usingx-ray diffraction (XRD), transmission electron microscopy (TEM) and magnetic measurements. The Rietveld refinementsof XRD data with space group Fm-3m clearly show the formation of A2 disordersingle phase and the lattice constant isfound to be 5.738 Å. The energy-dispersive x-ray spectroscopy (EDX) confirm the elemental composition close the desired values. The value of coercivity is found to be around 283 Oe and 126 Oe, measured at 10 K and 300 K, respectively. We observed the saturation magnetization significantly lower than expected from Slater-Pauling rule. This decrease in the magnetic moment might be due to the presence of amorphous SiO2 during the synthesis process. A large content of small size SiO2 particles along with Co2FeGa nanoparticles are also found in TEM study.

Consistent van der Waals Radii for the Whole Main Group

PubMed Central

Mantina, Manjeera; Chamberlin, Adam C.; Valero, Rosendo; Cramer, Christopher J.; Truhlar, Donald G.

2013-01-01

Atomic radii are not precisely defined but are nevertheless widely used parameters in modeling and understanding molecular structure and interactions. The van der Waals radii determined by Bondi from molecular crystals and noble gas crystals are the most widely used values, but Bondi recommended radius values for only 28 of the 44 main-group elements in the periodic table. In the present article we present atomic radii for the other 16; these new radii were determined in a way designed to be compatible with Bondi’s scale. The method chosen is a set of two-parameter correlations of Bondi’s radii with repulsive-wall distances calculated by relativistic coupled-cluster electronic structure calculations. The newly determined radii (in Å) are Be, 1.53; B, 1.92; Al, 1.84; Ca, 2.31; Ge, 2.11; Rb, 3.03; Sr, 2.50; Sb, 2.06; Cs, 3.43; Ba, 2.68; Bi, 2.07; Po, 1.97; At, 2.02; Rn, 2.20; Fr, 3.48; and Ra, 2.83. PMID:19382751

Consistent van der Waals radii for the whole main group.

PubMed

Mantina, Manjeera; Chamberlin, Adam C; Valero, Rosendo; Cramer, Christopher J; Truhlar, Donald G

2009-05-14

Atomic radii are not precisely defined but are nevertheless widely used parameters in modeling and understanding molecular structure and interactions. The van der Waals radii determined by Bondi from molecular crystals and data for gases are the most widely used values, but Bondi recommended radius values for only 28 of the 44 main-group elements in the periodic table. In the present Article, we present atomic radii for the other 16; these new radii were determined in a way designed to be compatible with Bondi's scale. The method chosen is a set of two-parameter correlations of Bondi's radii with repulsive-wall distances calculated by relativistic coupled-cluster electronic structure calculations. The newly determined radii (in A) are Be, 1.53; B, 1.92; Al, 1.84; Ca, 2.31; Ge, 2.11; Rb, 3.03; Sr, 2.49; Sb, 2.06; Cs, 3.43; Ba, 2.68; Bi, 2.07; Po, 1.97; At, 2.02; Rn, 2.20; Fr, 3.48; and Ra, 2.83.

40 CFR 405.113 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 28 2010-07-01 2010-07-01 true [Reserved] 405.113 Section 405.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS DAIRY PRODUCTS PROCESSING POINT SOURCE CATEGORY Condensed Whey Subcategory § 405.113 [Reserved] ...

40 CFR 51.113 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 2 2010-07-01 2010-07-01 false [Reserved] 51.113 Section 51.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS REQUIREMENTS FOR PREPARATION, ADOPTION, AND SUBMITTAL OF IMPLEMENTATION PLANS Control Strategy § 51.113 [Reserved] ...

48 CFR 432.113 - Customary contract financing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... financing. 432.113 Section 432.113 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Non-Commercial Item Purchase Financing 432.113 Customary contract financing. The contracting officer may determine the necessity for customary contract financing. The...

49 CFR 380.113 - Employer responsibilities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 5 2010-10-01 2010-10-01 false Employer responsibilities. 380.113 Section 380.113 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY....113 Employer responsibilities. (a) No motor carrier shall: (1) Allow, require, permit or authorize an...

7 CFR 1220.113 - Marketing.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false Marketing. 1220.113 Section 1220.113 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION Soybean Promotion and Research Order Definitions § 1220.113 Marketing. The term...

7 CFR 1220.113 - Marketing.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 10 2013-01-01 2013-01-01 false Marketing. 1220.113 Section 1220.113 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION Soybean Promotion and Research Order Definitions § 1220.113 Marketing. The term...

7 CFR 1220.113 - Marketing.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false Marketing. 1220.113 Section 1220.113 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION Soybean Promotion and Research Order Definitions § 1220.113 Marketing. The term...

7 CFR 1220.113 - Marketing.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Marketing. 1220.113 Section 1220.113 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION Soybean Promotion and Research Order Definitions § 1220.113 Marketing. The term...

42 CFR 66.113 - Publications.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Publications. 66.113 Section 66.113 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL RESEARCH SERVICE AWARDS Direct Awards § 66.113 Publications. Publication, distribution, and...

42 CFR 66.113 - Publications.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Publications. 66.113 Section 66.113 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL RESEARCH SERVICE AWARDS Direct Awards § 66.113 Publications. Publication, distribution, and...

42 CFR 66.113 - Publications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Publications. 66.113 Section 66.113 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL RESEARCH SERVICE AWARDS Direct Awards § 66.113 Publications. Publication, distribution, and...

42 CFR 66.113 - Publications.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Publications. 66.113 Section 66.113 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL RESEARCH SERVICE AWARDS Direct Awards § 66.113 Publications. Publication, distribution, and...

42 CFR 66.113 - Publications.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Publications. 66.113 Section 66.113 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL RESEARCH SERVICE AWARDS Direct Awards § 66.113 Publications. Publication, distribution, and...

32 CFR 724.113 - Application.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Application. 724.113 Section 724.113 National... Definitions § 724.113 Application. In the context of this Manual, a written application to the NDRB for the... must be used for the application. ...

Electronic structure and properties of MAu and MOH, where M = Tl and Nh: New data

NASA Astrophysics Data System (ADS)

Pershina, V.; Iliaš, M.

2018-02-01

Properties of the MAu and MOH (M = Tl and element 113, Nh) molecules were calculated using the 2c-DFT method. The obtained data are needed for evaluation of reactivity of Nh studied by gas-phase chromatography experiments. Results show that Nh should be less reactive (or more volatile) than Tl, both with respect to gold and the hydroxyl group. The reason for that are strong relativistic effects on the valence 7s and 7p electron shells. In difference to the atoms, NhOH may be less volatile than TlOH due to its larger both dipole moment and anisotropic polarizability.

Evaluation of an effective multifaceted implementation strategy for elective single-embryo transfer after in vitro fertilization.

PubMed

Kreuwel, I A M; van Peperstraten, A M; Hulscher, M E J L; Kremer, J A M; Grol, R P T M; Nelen, W L D M; Hermens, R P M G

2013-02-01

What is the relationship between the rate of elective single-embryo transfer (eSET) and couples' exposure to different elements of a multifaceted implementation strategy? Additional elements in a multifaceted implementation strategy do not result in an increased eSET rate. A multifaceted eSET implementation strategy with four different elements is effective in increasing the eSET rate by 11%. It is unclear whether every strategy element contributes equally to the strategy's effectiveness. An observational study was performed among 222 subfertile couples included in a previously performed randomized controlled trial. Of the 222 subfertile couples included, 109 couples received the implementation strategy and 113 couples received standard IVF care. A multivariate regression analysis assessed the effectiveness of four different strategy elements on the decision about the number embryos to be transferred. Questionnaires evaluated the experiences of couples with the different elements. Of the couples who received the implementation strategy, almost 50% (52/109) were exposed to all the four elements of the strategy. The remaining 57 couples who received two or three elements of the strategy could be divided into two further classes of exposure. Our analysis demonstrated that additional elements do not result in an increased eSET rate. In addition to the physician's advice, couples rated a decision aid and a counselling session as more important for their decision to transfer one or two embryos, compared with a phone call and a reimbursement offer (P < 0.001). The differences in eSET rate between exposure groups failed to reach significance, probably because of the small numbers of couples in each exposure group. Adding more elements to an implementation strategy does not always result in an increased effectiveness, which is in concordance with recent literature. This in-depth evaluation of a multifaceted intervention strategy could therefore help to modify strategies, by making them more effective and less expensive.

40 CFR 98.113 - Calculating GHG emissions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Calculating GHG emissions. 98.113 Section 98.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Ferroalloy Production § 98.113 Calculating GHG emissions. You...

40 CFR 89.113 - Smoke emission standard.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Smoke emission standard. 89.113 Section 89.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... and Certification Provisions § 89.113 Smoke emission standard. (a) Exhaust opacity from compression...

40 CFR 89.113 - Smoke emission standard.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Smoke emission standard. 89.113 Section 89.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... and Certification Provisions § 89.113 Smoke emission standard. (a) Exhaust opacity from compression...

40 CFR 89.113 - Smoke emission standard.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Smoke emission standard. 89.113 Section 89.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... and Certification Provisions § 89.113 Smoke emission standard. (a) Exhaust opacity from compression...

40 CFR 89.113 - Smoke emission standard.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Smoke emission standard. 89.113 Section 89.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... and Certification Provisions § 89.113 Smoke emission standard. (a) Exhaust opacity from compression...

13 CFR 113.510 - Recruitment.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Recruitment. 113.510 Section 113.510 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NONDISCRIMINATION IN FINANCIAL... Discrimination on the Basis of Sex in Employment in Education Programs Or Activities Prohibited § 113.510...

48 CFR 49.113 - Cost principles.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Cost principles. 49.113 Section 49.113 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS General Principles 49.113 Cost principles. The cost principles and procedures in the...

5 CFR 831.113 - Payments to children.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Payments to children. 831.113 Section 831.113 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) RETIREMENT Administration and General Provisions § 831.113 Payments to children. For purposes of...

5 CFR 831.113 - Payments to children.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Payments to children. 831.113 Section 831.113 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) RETIREMENT Administration and General Provisions § 831.113 Payments to children. For purposes of...

5 CFR 831.113 - Payments to children.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Payments to children. 831.113 Section 831.113 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) RETIREMENT Administration and General Provisions § 831.113 Payments to children. For purposes of...

5 CFR 831.113 - Payments to children.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Payments to children. 831.113 Section 831.113 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) RETIREMENT Administration and General Provisions § 831.113 Payments to children. For purposes of...

5 CFR 831.113 - Payments to children.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Payments to children. 831.113 Section 831.113 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) RETIREMENT Administration and General Provisions § 831.113 Payments to children. For purposes of...

40 CFR 113.2 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Applicability. 113.2 Section 113.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.2 Applicability. This subpart applies to...

40 CFR 113.1 - Purpose.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Purpose. 113.1 Section 113.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.1 Purpose. This subpart establishes size...

40 CFR 113.3 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Definitions. 113.3 Section 113.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.3 Definitions. As used in this subpart...

40 CFR 113.1 - Purpose.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Purpose. 113.1 Section 113.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.1 Purpose. This subpart establishes size...

40 CFR 113.5 - Exclusions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Exclusions. 113.5 Section 113.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.5 Exclusions. This subpart does not apply...

40 CFR 113.3 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Definitions. 113.3 Section 113.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.3 Definitions. As used in this subpart...

40 CFR 113.5 - Exclusions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Exclusions. 113.5 Section 113.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.5 Exclusions. This subpart does not apply...

40 CFR 113.2 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Applicability. 113.2 Section 113.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS LIABILITY LIMITS FOR SMALL ONSHORE STORAGE FACILITIES Oil Storage Facilities § 113.2 Applicability. This subpart applies to...

18 CFR 388.113 - Accessing critical energy infrastructure information.

Code of Federal Regulations, 2014 CFR

2014-04-01

... energy infrastructure information. 388.113 Section 388.113 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES INFORMATION AND REQUESTS § 388.113 Accessing critical energy infrastructure information. (a) Scope. This section governs access to...

18 CFR 388.113 - Accessing critical energy infrastructure information.

Code of Federal Regulations, 2010 CFR

2010-04-01

... energy infrastructure information. 388.113 Section 388.113 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES INFORMATION AND REQUESTS § 388.113 Accessing critical energy infrastructure information. (a) Scope. This section governs access to...

18 CFR 388.113 - Accessing critical energy infrastructure information.

Code of Federal Regulations, 2012 CFR

2012-04-01

... energy infrastructure information. 388.113 Section 388.113 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES INFORMATION AND REQUESTS § 388.113 Accessing critical energy infrastructure information. (a) Scope. This section governs access to...

18 CFR 388.113 - Accessing critical energy infrastructure information.

Code of Federal Regulations, 2013 CFR

2013-04-01

... energy infrastructure information. 388.113 Section 388.113 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES INFORMATION AND REQUESTS § 388.113 Accessing critical energy infrastructure information. (a) Scope. This section governs access to...

18 CFR 388.113 - Accessing critical energy infrastructure information.

Code of Federal Regulations, 2011 CFR

2011-04-01

... energy infrastructure information. 388.113 Section 388.113 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES INFORMATION AND REQUESTS § 388.113 Accessing critical energy infrastructure information. (a) Scope. This section governs access to...

14 CFR 1240.113 - Financial accounting.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Financial accounting. 1240.113 Section 1240.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INVENTIONS AND CONTRIBUTIONS Awards for Scientific and Technical Contributions § 1240.113 Financial accounting. (a) An Award Check...

Dental Abnormalities Caused by Novel Compound Heterozygous CTSK Mutations.

PubMed

Xue, Y; Wang, L; Xia, D; Li, Q; Gao, S; Dong, M; Cai, T; Shi, S; He, L; Hu, K; Mao, T; Duan, X

2015-05-01

Cathepsin K (CTSK) is an important protease responsible for degrading type I collagen, osteopontin, and other bone matrix proteins. The mutations in the CTSK gene can cause pycnodysostosis (OMIM 265800), a rare autosomal recessive bone dysplasia. Patients with pycnodysostosis have been reported to present specific dental abnormalities; however, whether these dental abnormalities are related to dysfunctional CTSK has never been reported. Here we investigated the histologic changes of cementum and alveolar bone in a pycnodysostosis patient, caused by novel compound heterozygous mutations in the CTSK gene (c.87 G>A p.W29X and c.848 A>G p.Y283C). The most impressive manifestations in tooth were extensive periradicular high-density clumps with unclear periodontal space by orthopantomography examination and micro-computed tomography scanning analysis. Hematoxylin/eosin and toluidine blue staining and atomic force microscopy analysis showed that the cementum became significantly thickened, softened, and full of cementocytes. The disorganized bone structure was the main character of alveolar bone. The p.W29X mutation may represent the loss-of-function allele with an earlier termination codon in the precursor CTSK polypeptide. Residue Y283 is highly conserved among papain-like cysteine proteases. Three-dimensional structure modeling analysis found that the loss of the hydroxybenzene residue in the Y283C mutation would interrupt the hydrogen network and possibly affect the self-cleavage of the CTSK enzyme. Furthermore, p.Y283C mutation did not affect the mRNA and protein levels of overexpressed CTSK in COS-7 system but did reduce CTSK enzyme activity. In conclusion, the histologic and ultrastructural changes of cementum and alveolar bone might be affected by CTSK mutation via reduction of its enzyme activity (clinical trial registration: ChiCTR-TNC-10000876). © International & American Associations for Dental Research 2015.

THG113.31, a specific PGF2alpha receptor antagonist, induces human myometrial relaxation and BKCa channel activation

PubMed Central

Doheny, Helen C; O'Reilly, Michael J; Sexton, Donal J; Morrison, John J

2007-01-01

Background PGF2alpha exerts a significant contractile effect on myometrium and is central to human labour. THG113.31, a specific non-competitive PGF2alpha receptor (FP) antagonist, exerts an inhibitory effect on myometrial contractility. The BKCa channel is ubiquitously encountered in human uterine tissue and plays a significant role in modulating myometrial cell membrane potential and excitability. The objective of this study was to investigate potential BKCa channel involvement in the response of human myometrium to THG113.31. Methods Single and whole-cell electrophysiological BKCa channel recordings from freshly dispersed myocytes, were investigated in the presence and absence of THG113.31. Functional studies investigated the effects of THG113.31 on isolated spontaneous myometrial contractions, in the presence and absence of the BKCa channel blocker, iberiotoxin. Results Single channel recordings identified the BKCa channel as a target of THG113.31. THG113.31 significantly increased the open state probability of these channels [control 0.023+/-0.006; 10 microM THG113.31 0.087+/-0.012 (P = 0.009); and 50 microM THG113.31 0.1356+/-0.018 (P = 0.001)]. In addition, THG113.31 increased whole-cell BKCa currents over a range of membrane potentials, and this effect was reversed by 100 nanoM IbTX. Isometric tension studies demonstrated that THG113.31 exerted a significant concentration-dependent relaxant effect on human myometrial tissue and pre-incubation of strips with IbTX abolished this effect on spontaneously occurring contractions. Conclusion These data suggests that activation of the BKCa channel may contribute, at least partially, to the uterorelaxant effect of THG113.31. PMID:17367527

Does serum uric acid predict incident metabolic syndrome in a population with high prevalence of obesity?

PubMed Central

Ferrara, Liberato Aldo; Wang, Hong; Umans, Jason G; Franceschini, Nora; Jolly, Stacey; Lee, Elisa T.; Yeh, Jeunliang; Devereux, Richard B.; Howard, Barbara V.; de Simone, Giovanni

2014-01-01

Objective To evaluate whether uric acid (UA) predicts 4-yr incidence of metabolic syndrome (MetS) in non-diabetic participants of the Strong Heart Study (SHS) cohort. Design and Methods In this population-based prospective study we analyzed 1499 American Indians (890 women), without diabetes or MetS, controlled during the 4th SHS exam and reexamined 4 years later during the 5th SHS exam. Participants were divided into sex-specific tertiles of UA and the first two tertiles (group N) were compared with the third tertile (group H). Results Body mass index (BMI =28.3±7 vs. 31.1±7 kg/m2), fat-free mass (FFM = 52.0±14 vs. 54.9±11 kg), waist-to-hip ratio, HOMA-IR (3.66 vs. 4.26), BP and indices of inflammation were significantly higher in group H than in group N (all p<0.001). Incident MetS at the time of the 5th exam was more frequent in group H than group N (35 vs. 28%, OR 1.44 (95% CI=1.10-1.91; p< 0.01). This association was still significant (OR= 1.13, p=0.04) independently of family relatedness, sex, history of hypertension, HOMA-IR, central adiposity and renal function, but disappeared when fat-free mass was included in the model. Conclusions In the SHS, UA levels are associated to parameters of insulin resistance and to indices of inflammation. UA levels, however, do not predict incident MetS independently of the initial obesity-related increased FFM. PMID:25063537

Noninvasive detection of hepatic steatosis in patients without ultrasonographic evidence of fatty liver using the controlled attenuation parameter evaluated with transient elastography.

PubMed

Yilmaz, Yusuf; Ergelen, Rabia; Akin, Hakan; Imeryuz, Nese

2013-11-01

Although ultrasound is a useful technique for detecting hepatic steatosis, it cannot provide a precise determination of hepatic fat content. A novel attenuation parameter named controlled attenuation parameter (CAP) has been developed to process the raw ultrasonic signals acquired by Fibroscan. The aim of this study was to determine the percentage of hepatic steatosis in apparently healthy Turkish individuals using the proposed diagnostic cut-off points for CAP. In addition, we sought to investigate the association of CAP with the traditional risk factors for nonalcoholic fatty liver disease in a screening setting. In the present study, 102 Turkish individuals without evidence of fatty liver on ultrasound and normal aminotransferase levels underwent CAP measurements by means of Fibroscan. The mean (SD), median (minimum-maximum), and 5th and 95th percentile values of CAP values in this cohort of 102 individuals were 206.99 (48.12), 210.5 (100.0-314.0), 113.4 and 280.2 dB/m, respectively. Using the cut-offs of 222, 238, and 283 dB/m for CAP, there were 39 (38.2%), 23 (22.5%), and five (4.9%) individuals out of 102 who had at least 10% steatosis despite normal liver findings on ultrasound. After allowance for potential confounders, CAP was independently associated with BMI (β=0.39, t=3.5, P<0.001) and the number of metabolic syndrome criteria (β=0.24, t=2.1, P<0.05). These results hold promise for early noninvasive detection of hepatic steatosis on the basis of CAP assessment.

[Prevalence of cardiovascular and metabolic risk factors in school students, university students, and women from community-based organizations in the districts of Lima, Callao, la Libertad and Arequipa, Peru 2011].

PubMed

Núñez-Robles, Eloísa; Huapaya-Pizarro, Cleopatra; Torres-Lao, Rogger; Esquivel-León, Silvia; Suarez-Moreno, Víctor; Yasuda-Espinoza, Myriam; Sanjinés-López, Giovanna

2014-01-01

To determine the prevalence of arterial hypertension, and cardiovascular and metabolic risk factors in school students, college students and women from community-based organizations (CBO) in four districts in Peru. Cross-sectional study conducted in 2011 in the districts of Lima, Callao, La Libertad and Arequipa with school students, university students and women from CBOs. A survey, anthropometric measurements, blood pressure measurements and fasting blood sampling were conducted to determine glucose and lipid levels. Thus, prevalence of overweight, hypertension, hypercholesterolemia, suspected diabetes, and other variables, were calculated. The main outcome variable was prevalence of overweight. 1,127 people were included: 283 (25.1%) school students, 431 (38.3%) university students, and 413 women (36.6%) from CBOs. Non-response rates were 3%, 0% and 8%, respectively. The average ages in the three groups were 14.3 ± 0.9; 19.6 ± 2.8; and 46.1 ± 15.3 years, respectively. Prevalence of overweight/obesity (BMI ≥ 25) was 11.3%, 20.9%, and 73.4%; hypertension was 0.7%; 1.2%, and 12.8%; high cholesterol (≥ 200 mg/dL) was 5.2%, 11.5%, and 50.1%; and suspected diabetes was 1.4%; 1.0%, and 20.3% respectively in each group of school students, university students and women from CBOs. The prevalence of cardiovascular and metabolic risk factors generally increased in older age groups. In school and university aged groups, the most frequent problems were overweight and obesity, particularly abdominal obesity.

Trematode Metacercariae in Freshwater Fish from Water Systems of Hantangang and Imjingang in Republic of Korea

PubMed Central

Sohn, Woon-Mok; Na, Byoung-Kuk; Cho, Shin-Hyeong; Lee, Soon-Won; Choi, Seung-Bong; Seok, Won-Seok

2015-01-01

The infection status of freshwater fish with digenetic trematode metacercariae was examined in water systems of Hantangang and Imjingang (River), the Republic of Korea. A total of 877 (594 from Hantangang and 283 from Imjingang) fishes were examined by the artificial digestion methods. Clonorchis sinensis metacercariae were detected in 7 (1.2%) fishes (in 3 spp.) from Hantangang in Cheorwon-gun, Gangwon-do, and 40 (14.1%) fishes (in 7 spp.) from Munsancheon in Paju-si, Gyeonggi-do. The average densities were 1.9 and 35.6 per fish infected, respectively. Metagonimus spp. metacercariae were detected in 312 (52.5%) and 113 (39.9%) fishes from Hantangang and Imjingang, and their average densities were 47.5 and 9.6 per fish infected, respectively. Centrocestus armatus metacercariae were found in 161 (27.1%) and 70 (24.7%) fishes from Hantangang and Imjingang, and their average number per fish infected was 694 and 82, respectively. Echinostoma spp. metacercariae were detected in 50 (8.4%) and 94 (33.2%) fishes from Hantangang and Imjingang, and their average densities were 9.6 and 23.1 per fish infected, respectively. The infection status of fishes with metacercariae of Stephanoprora spp., Diplostomum spp., Clinostomum complanatum, Metorchis orientalis, and Metorchis taiwanensis were analyzed by surveyed regions. Conclusively, it was confirmed that C. sinensis metacercariae were quite commonly detected in fishes from Munsancheon but rarely from other localities, whereas the metacercariae of other digenetic trematodes were relatively prevalent in fishes from water systems of Hantangang and Imjingang in Korea. PMID:26174822

14 CFR 1245.113 - Hearing procedure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Hearing procedure. 1245.113 Section 1245.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PATENTS AND OTHER INTELLECTUAL PROPERTY RIGHTS Patent Waiver Regulations § 1245.113 Hearing procedure. (a) If the petitioner requests an...

28 CFR 551.113 - Counseling.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Counseling. 551.113 Section 551.113... Pretrial Inmates § 551.113 Counseling. (a) When consistent with institution security and good order, pretrial inmates may be allowed the opportunity to receive counseling services with convicted inmates. (b...

28 CFR 551.113 - Counseling.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Counseling. 551.113 Section 551.113... Pretrial Inmates § 551.113 Counseling. (a) When consistent with institution security and good order, pretrial inmates may be allowed the opportunity to receive counseling services with convicted inmates. (b...

28 CFR 551.113 - Counseling.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Counseling. 551.113 Section 551.113... Pretrial Inmates § 551.113 Counseling. (a) When consistent with institution security and good order, pretrial inmates may be allowed the opportunity to receive counseling services with convicted inmates. (b...

28 CFR 551.113 - Counseling.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Counseling. 551.113 Section 551.113... Pretrial Inmates § 551.113 Counseling. (a) When consistent with institution security and good order, pretrial inmates may be allowed the opportunity to receive counseling services with convicted inmates. (b...

28 CFR 551.113 - Counseling.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Counseling. 551.113 Section 551.113... Pretrial Inmates § 551.113 Counseling. (a) When consistent with institution security and good order, pretrial inmates may be allowed the opportunity to receive counseling services with convicted inmates. (b...

13 CFR 113.130 - Effect of employment opportunities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Effect of employment opportunities. 113.130 Section 113.130 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NONDISCRIMINATION... Financial Assistance Introduction § 113.130 Effect of employment opportunities. The obligation to comply...

40 CFR 89.113 - Smoke emission standard.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Smoke emission standard. 89.113 Section 89.113 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED... Certification Provisions § 89.113 Smoke emission standard. (a) Exhaust opacity from compression-ignition nonroad...

46 CFR 113.05-7 - Environmental tests.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Environmental tests. 113.05-7 Section 113.05-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT General Provisions § 113.05-7 Environmental tests. Communication, alarm system...

24 CFR 886.113 - Physical condition standard; physical inspection requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Physical condition standard; physical inspection requirements. 886.113 Section 886.113 Housing and Urban Development Regulations... § 886.113 Physical condition standard; physical inspection requirements. (a) General. Housing used in...

24 CFR 886.113 - Physical condition standard; physical inspection requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Physical condition standard; physical inspection requirements. 886.113 Section 886.113 Housing and Urban Development REGULATIONS... § 886.113 Physical condition standard; physical inspection requirements. (a) General. Housing used in...

24 CFR 886.113 - Physical condition standard; physical inspection requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Physical condition standard; physical inspection requirements. 886.113 Section 886.113 Housing and Urban Development REGULATIONS... § 886.113 Physical condition standard; physical inspection requirements. (a) General. Housing used in...

24 CFR 886.113 - Physical condition standard; physical inspection requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Physical condition standard; physical inspection requirements. 886.113 Section 886.113 Housing and Urban Development REGULATIONS... § 886.113 Physical condition standard; physical inspection requirements. (a) General. Housing used in...

24 CFR 886.113 - Physical condition standard; physical inspection requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Physical condition standard; physical inspection requirements. 886.113 Section 886.113 Housing and Urban Development REGULATIONS... § 886.113 Physical condition standard; physical inspection requirements. (a) General. Housing used in...

47 CFR 5.113 - Adherence to program of research.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Adherence to program of research. 5.113 Section 5.113 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL EXPERIMENTAL RADIO SERVICE (OTHER THAN BROADCAST) Technical Standards and Operating Requirements § 5.113 Adherence to program of research...

46 CFR 113.30-1 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Applicability. 113.30-1 Section 113.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Internal Communications § 113.30-1 Applicability. This subpart applies to each self...

46 CFR 113.40-1 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Applicability. 113.40-1 Section 113.40-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Rudder Angle Indicator Systems § 113.40-1 Applicability. This subpart applies to...

46 CFR 113.30-1 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Applicability. 113.30-1 Section 113.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Internal Communications § 113.30-1 Applicability. This subpart applies to each self...

46 CFR 113.30-1 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Applicability. 113.30-1 Section 113.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Internal Communications § 113.30-1 Applicability. This subpart applies to each self...

46 CFR 113.30-1 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Applicability. 113.30-1 Section 113.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Internal Communications § 113.30-1 Applicability. This subpart applies to each self...

46 CFR 113.40-1 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Applicability. 113.40-1 Section 113.40-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Rudder Angle Indicator Systems § 113.40-1 Applicability. This subpart applies to...

46 CFR 113.30-1 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Applicability. 113.30-1 Section 113.30-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Internal Communications § 113.30-1 Applicability. This subpart applies to each self...

46 CFR 113.40-1 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Applicability. 113.40-1 Section 113.40-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Rudder Angle Indicator Systems § 113.40-1 Applicability. This subpart applies to...

23 CFR 470.113 - National Highway System procedures.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false National Highway System procedures. 470.113 Section 470.113 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH HIGHWAY SYSTEMS Federal-aid Highway Systems § 470.113 National Highway System procedures. (a) Proposals...

23 CFR 470.113 - National Highway System procedures.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false National Highway System procedures. 470.113 Section 470.113 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH HIGHWAY SYSTEMS Federal-aid Highway Systems § 470.113 National Highway System procedures. (a) Proposals...

23 CFR 470.113 - National Highway System procedures.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 23 Highways 1 2012-04-01 2012-04-01 false National Highway System procedures. 470.113 Section 470.113 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH HIGHWAY SYSTEMS Federal-aid Highway Systems § 470.113 National Highway System procedures. (a) Proposals...

23 CFR 470.113 - National Highway System procedures.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false National Highway System procedures. 470.113 Section 470.113 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH HIGHWAY SYSTEMS Federal-aid Highway Systems § 470.113 National Highway System procedures. (a) Proposals...

23 CFR 470.113 - National Highway System procedures.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false National Highway System procedures. 470.113 Section 470.113 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH HIGHWAY SYSTEMS Federal-aid Highway Systems § 470.113 National Highway System procedures. (a) Proposals...

42 CFR 53.113 - Community service.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Community service. 53.113 Section 53.113 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS, LOANS AND LOAN... To Pay; Community Service; Nondiscrimination. § 53.113 Community service. (a) Applicability. The...

46 CFR 113.40-1 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Applicability. 113.40-1 Section 113.40-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Rudder Angle Indicator Systems § 113.40-1 Applicability. This subpart applies to...

46 CFR 113.40-1 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Applicability. 113.40-1 Section 113.40-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Rudder Angle Indicator Systems § 113.40-1 Applicability. This subpart applies to...

Lunar bulk chemical composition: a post-Gravity Recovery and Interior Laboratory reassessment

PubMed Central

Taylor, G. Jeffrey; Wieczorek, Mark A.

2014-01-01

New estimates of the thickness of the lunar highlands crust based on data from the Gravity Recovery and Interior Laboratory mission, allow us to reassess the abundances of refractory elements in the Moon. Previous estimates of the Moon fall into two distinct groups: earthlike and a 50% enrichment in the Moon compared with the Earth. Revised crustal thicknesses and compositional information from remote sensing and lunar samples indicate that the crust contributes 1.13–1.85 wt% Al2O3 to the bulk Moon abundance. Mare basalt Al2O3 concentrations (8–10 wt%) and Al2O3 partitioning behaviour between melt and pyroxene during partial melting indicate mantle Al2O3 concentration in the range 1.3–3.1 wt%, depending on the relative amounts of pyroxene and olivine. Using crustal and mantle mass fractions, we show that that the Moon and the Earth most likely have the same (within 20%) concentrations of refractory elements. This allows us to use correlations between pairs of refractory and volatile elements to confirm that lunar abundances of moderately volatile elements such as K, Rb and Cs are depleted by 75% in the Moon compared with the Earth and that highly volatile elements, such as Tl and Cd, are depleted by 99%. The earthlike refractory abundances and depleted volatile abundances are strong constraints on lunar formation processes. PMID:25114309

Human Streptococcus agalactiae strains in aquatic mammals and fish

PubMed Central

2013-01-01

Background In humans, Streptococcus agalactiae or group B streptococcus (GBS) is a frequent coloniser of the rectovaginal tract, a major cause of neonatal infectious disease and an emerging cause of disease in non-pregnant adults. In addition, Streptococcus agalactiae causes invasive disease in fish, compromising food security and posing a zoonotic hazard. We studied the molecular epidemiology of S. agalactiae in fish and other aquatic species to assess potential for pathogen transmission between aquatic species and humans. Methods Isolates from fish (n = 26), seals (n = 6), a dolphin and a frog were characterized by pulsed-field gel electrophoresis, multilocus sequence typing and standardized 3-set genotyping, i.e. molecular serotyping and profiling of surface protein genes and mobile genetic elements. Results Four subpopulations of S. agalactiae were identified among aquatic isolates. Sequence type (ST) 283 serotype III-4 and its novel single locus variant ST491 were detected in fish from Southeast Asia and shared a 3-set genotype identical to that of an emerging ST283 clone associated with invasive disease of adult humans in Asia. The human pathogenic strain ST7 serotype Ia was also detected in fish from Asia. ST23 serotype Ia, a subpopulation that is normally associated with human carriage, was found in all grey seals, suggesting that human effluent may contribute to microbial pollution of surface water and exposure of sea mammals to human pathogens. The final subpopulation consisted of non-haemolytic ST260 and ST261 serotype Ib isolates, which belong to a fish-associated clonal complex that has never been reported from humans. Conclusions The apparent association of the four subpopulations of S. agalactiae with specific groups of host species suggests that some strains of aquatic S. agalactiae may present a zoonotic or anthroponotic hazard. Furthermore, it provides a rational framework for exploration of pathogenesis and host-associated genome content of S. agalactiae strains. PMID:23419028

49 CFR 385.113 - Administrative review.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 5 2010-10-01 2010-10-01 false Administrative review. 385.113 Section 385.113... Safety Monitoring System for Mexico-Domiciled Carriers § 385.113 Administrative review. (a) A Mexico-domiciled motor carrier may request the FMCSA to conduct an administrative review if it believes the FMCSA...

14 CFR 1245.113 - Hearing procedure.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Hearing procedure. 1245.113 Section 1245.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PATENTS AND OTHER INTELLECTUAL PROPERTY RIGHTS Patent Waiver Regulations § 1245.113 Hearing procedure. (a) If the petitioner requests an oral...

19 CFR 113.35 - Individual sureties.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 1 2012-04-01 2012-04-01 false Individual sureties. 113.35 Section 113.35 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS BONDS Principals and Sureties § 113.35 Individual sureties. (a) Number required. If individuals...

19 CFR 113.35 - Individual sureties.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Individual sureties. 113.35 Section 113.35 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS BONDS Principals and Sureties § 113.35 Individual sureties. (a) Number required. If individuals...

19 CFR 113.35 - Individual sureties.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 1 2013-04-01 2013-04-01 false Individual sureties. 113.35 Section 113.35 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS BONDS Principals and Sureties § 113.35 Individual sureties. (a) Number required. If individuals...

19 CFR 113.35 - Individual sureties.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 1 2011-04-01 2011-04-01 false Individual sureties. 113.35 Section 113.35 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS BONDS Principals and Sureties § 113.35 Individual sureties. (a) Number required. If individuals...

46 CFR 113.25-3 - Requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Requirements. 113.25-3 Section 113.25-3 Shipping COAST... SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-3 Requirements. Each vessel must have a general emergency alarm system that meets the requirements of this subpart. ...

46 CFR 113.25-3 - Requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Requirements. 113.25-3 Section 113.25-3 Shipping COAST... SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-3 Requirements. Each vessel must have a general emergency alarm system that meets the requirements of this subpart. ...

46 CFR 113.25-3 - Requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Requirements. 113.25-3 Section 113.25-3 Shipping COAST... SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-3 Requirements. Each vessel must have a general emergency alarm system that meets the requirements of this subpart. ...

5 CFR 550.113 - Computation of overtime pay.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Computation of overtime pay. 550.113 Section 550.113 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY ADMINISTRATION (GENERAL) Premium Pay Overtime Pay § 550.113 Computation of overtime pay. (a) For each employee...

10 CFR 1303.113 - Business information.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Business information. 1303.113 Section 1303.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.113 Business information. (a) In general. Business information obtained by the Board from a submitter shall be disclosed under the...

49 CFR 1.13 - OST Key Responsibilities.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 1 2013-10-01 2013-10-01 false OST Key Responsibilities. 1.13 Section 1.13... of the Secretary § 1.13 OST Key Responsibilities. (a) The OST is responsible for: (1) Providing... Government; (5) Encouraging maximum private development of transportation services; (6) Providing responsive...

49 CFR 1.13 - OST Key Responsibilities.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 1 2012-10-01 2012-10-01 false OST Key Responsibilities. 1.13 Section 1.13... of the Secretary § 1.13 OST Key Responsibilities. (a) The OST is responsible for: (1) Providing... Government; (5) Encouraging maximum private development of transportation services; (6) Providing responsive...

49 CFR 1.13 - OST Key Responsibilities.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 1 2014-10-01 2014-10-01 false OST Key Responsibilities. 1.13 Section 1.13... of the Secretary § 1.13 OST Key Responsibilities. (a) The OST is responsible for: (1) Providing... Government; (5) Encouraging maximum private development of transportation services; (6) Providing responsive...

46 CFR 113.27-1 - Engineers' assistance-needed alarm.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Engineers' assistance-needed alarm. 113.27-1 Section 113.27-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engineers' Assistance-Needed Alarm § 113.27-1 Engineers...

46 CFR 113.27-1 - Engineers' assistance-needed alarm.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Engineers' assistance-needed alarm. 113.27-1 Section 113.27-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engineers' Assistance-Needed Alarm § 113.27-1 Engineers...

46 CFR 113.27-1 - Engineers' assistance-needed alarm.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Engineers' assistance-needed alarm. 113.27-1 Section 113.27-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engineers' Assistance-Needed Alarm § 113.27-1 Engineers...

46 CFR 113.27-1 - Engineers' assistance-needed alarm.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Engineers' assistance-needed alarm. 113.27-1 Section 113.27-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engineers' Assistance-Needed Alarm § 113.27-1 Engineers...

46 CFR 113.27-1 - Engineers' assistance-needed alarm.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Engineers' assistance-needed alarm. 113.27-1 Section 113.27-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engineers' Assistance-Needed Alarm § 113.27-1 Engineers...

13 CFR 113.3-3 - Structural accommodations for handicapped clients.

Code of Federal Regulations, 2013 CFR

2013-01-01

... handicapped clients. 113.3-3 Section 113.3-3 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION... ADMINISTRATOR General Provisions § 113.3-3 Structural accommodations for handicapped clients. (a) Existing... by handicapped clients. Where structural changes are necessary to make the recipient's goods or...

13 CFR 113.3-3 - Structural accommodations for handicapped clients.

Code of Federal Regulations, 2012 CFR

2012-01-01

... handicapped clients. 113.3-3 Section 113.3-3 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION... ADMINISTRATOR General Provisions § 113.3-3 Structural accommodations for handicapped clients. (a) Existing... by handicapped clients. Where structural changes are necessary to make the recipient's goods or...

13 CFR 113.3-3 - Structural accommodations for handicapped clients.

Code of Federal Regulations, 2014 CFR

2014-01-01

... handicapped clients. 113.3-3 Section 113.3-3 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION... ADMINISTRATOR General Provisions § 113.3-3 Structural accommodations for handicapped clients. (a) Existing... by handicapped clients. Where structural changes are necessary to make the recipient's goods or...

13 CFR 113.3-3 - Structural accommodations for handicapped clients.

Code of Federal Regulations, 2010 CFR

2010-01-01

... handicapped clients. 113.3-3 Section 113.3-3 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION... ADMINISTRATOR General Provisions § 113.3-3 Structural accommodations for handicapped clients. (a) Existing... by handicapped clients. Where structural changes are necessary to make the recipient's goods or...

23 CFR 668.113 - Program and project procedures.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Program and project procedures. 668.113 Section 668.113 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS EMERGENCY RELIEF PROGRAM Procedures for Federal-Aid Highways § 668.113 Program and project procedures. (a...

10 CFR 1303.113 - Business information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Business information. 1303.113 Section 1303.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.113 Business information. (a) In general. Business information obtained by the Board from a submitter shall be disclosed under the...

7 CFR 1150.113 - Fluid milk products.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 9 2014-01-01 2013-01-01 true Fluid milk products. 1150.113 Section 1150.113... AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.113 Fluid milk products. Fluid milk products means those milk products normally...

7 CFR 1150.113 - Fluid milk products.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 9 2012-01-01 2012-01-01 false Fluid milk products. 1150.113 Section 1150.113... Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.113 Fluid milk products. Fluid milk products means those milk products normally...

7 CFR 1150.113 - Fluid milk products.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 9 2013-01-01 2013-01-01 false Fluid milk products. 1150.113 Section 1150.113... AGREEMENTS AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.113 Fluid milk products. Fluid milk products means those milk products normally...

29 CFR 1910.112-1910.113 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 5 2012-07-01 2012-07-01 false [Reserved] 1910.112-1910.113 Section 1910.112-1910.113 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR OCCUPATIONAL SAFETY AND HEALTH STANDARDS Hazardous Materials §§ 1910.112-1910.113...

10 CFR 71.113 - Document control.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Document control. 71.113 Section 71.113 Energy NUCLEAR....113 Document control. The licensee, certificate holder, and applicant for a CoC shall establish measures to control the issuance of documents such as instructions, procedures, and drawings, including...

10 CFR 71.113 - Document control.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Document control. 71.113 Section 71.113 Energy NUCLEAR....113 Document control. The licensee, certificate holder, and applicant for a CoC shall establish measures to control the issuance of documents such as instructions, procedures, and drawings, including...

10 CFR 71.113 - Document control.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Document control. 71.113 Section 71.113 Energy NUCLEAR....113 Document control. The licensee, certificate holder, and applicant for a CoC shall establish measures to control the issuance of documents such as instructions, procedures, and drawings, including...

46 CFR 113.50-1 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Applicability. 113.50-1 Section 113.50-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Public Address Systems § 113.50-1 Applicability. This subpart applies to each vessel...

46 CFR 113.37-1 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Applicability. 113.37-1 Section 113.37-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Shaft Speed and Thrust Indicators § 113.37-1 Applicability. This subpart applies to...

46 CFR 113.50-1 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Applicability. 113.50-1 Section 113.50-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Public Address Systems § 113.50-1 Applicability. This subpart applies to each vessel...

46 CFR 113.50-1 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Applicability. 113.50-1 Section 113.50-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Public Address Systems § 113.50-1 Applicability. This subpart applies to each vessel...

46 CFR 113.50-1 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Applicability. 113.50-1 Section 113.50-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Public Address Systems § 113.50-1 Applicability. This subpart applies to each vessel...

46 CFR 113.50-1 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Applicability. 113.50-1 Section 113.50-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Public Address Systems § 113.50-1 Applicability. This subpart applies to each vessel...

46 CFR 113.37-1 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Applicability. 113.37-1 Section 113.37-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Shaft Speed and Thrust Indicators § 113.37-1 Applicability. This subpart applies to...

46 CFR 113.37-1 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Applicability. 113.37-1 Section 113.37-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Shaft Speed and Thrust Indicators § 113.37-1 Applicability. This subpart applies to...

13 CFR 113.135 - Designation of responsible employee and adoption of grievance procedures.

Code of Federal Regulations, 2010 CFR

2010-01-01

... employee and adoption of grievance procedures. 113.135 Section 113.135 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NONDISCRIMINATION IN FINANCIAL ASSISTANCE PROGRAMS OF SBA-EFFECTUATION OF POLICIES... Programs or Activities Receiving Federal Financial Assistance Introduction § 113.135 Designation of...

49 CFR 229.113 - Warning notice.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 4 2014-10-01 2014-10-01 false Warning notice. 229.113 Section 229.113....113 Warning notice. Whenever any steam generator has been shut down because of defects, a distinctive warning notice giving reasons for the shut-down shall be conspicuously attached near the steam generator...

49 CFR 229.113 - Warning notice.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 4 2013-10-01 2013-10-01 false Warning notice. 229.113 Section 229.113....113 Warning notice. Whenever any steam generator has been shut down because of defects, a distinctive warning notice giving reasons for the shut-down shall be conspicuously attached near the steam generator...

49 CFR 229.113 - Warning notice.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 4 2010-10-01 2010-10-01 false Warning notice. 229.113 Section 229.113....113 Warning notice. Whenever any steam generator has been shut down because of defects, a distinctive warning notice giving reasons for the shut-down shall be conspicuously attached near the steam generator...

49 CFR 229.113 - Warning notice.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 4 2012-10-01 2012-10-01 false Warning notice. 229.113 Section 229.113....113 Warning notice. Whenever any steam generator has been shut down because of defects, a distinctive warning notice giving reasons for the shut-down shall be conspicuously attached near the steam generator...

49 CFR 229.113 - Warning notice.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 4 2011-10-01 2011-10-01 false Warning notice. 229.113 Section 229.113....113 Warning notice. Whenever any steam generator has been shut down because of defects, a distinctive warning notice giving reasons for the shut-down shall be conspicuously attached near the steam generator...

10 CFR 1303.113 - Business information.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Business information. 1303.113 Section 1303.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.113 Business information. (a) In general. Business information obtained by the Board from a submitter shall be disclosed under the...

10 CFR 1303.113 - Business information.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Business information. 1303.113 Section 1303.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.113 Business information. (a) In general. Business information obtained by the Board from a submitter shall be disclosed under the...

10 CFR 1303.113 - Business information.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Business information. 1303.113 Section 1303.113 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PUBLIC INFORMATION AND REQUESTS § 1303.113 Business information. (a) In general. Business information obtained by the Board from a submitter shall be disclosed under the...

7 CFR 1150.113 - Fluid milk products.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 9 2011-01-01 2011-01-01 false Fluid milk products. 1150.113 Section 1150.113... Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.113 Fluid milk products. Fluid milk products means those milk products normally...

7 CFR 1150.113 - Fluid milk products.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 9 2010-01-01 2009-01-01 true Fluid milk products. 1150.113 Section 1150.113... Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.113 Fluid milk products. Fluid milk products means those milk products normally...

46 CFR 113.35-1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Definitions. 113.35-1 Section 113.35-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-1 Definitions. As used in this subpart: (a...

21 CFR 113.60 - Containers.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Containers. 113.60 Section 113.60 Food and Drugs... CONSUMPTION THERMALLY PROCESSED LOW-ACID FOODS PACKAGED IN HERMETICALLY SEALED CONTAINERS Control of Components, Food Product Containers, Closures, and In-Process Materials § 113.60 Containers. (a) Closures...

21 CFR 113.60 - Containers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Containers. 113.60 Section 113.60 Food and Drugs... CONSUMPTION THERMALLY PROCESSED LOW-ACID FOODS PACKAGED IN HERMETICALLY SEALED CONTAINERS Control of Components, Food Product Containers, Closures, and In-Process Materials § 113.60 Containers. (a) Closures...

21 CFR 113.60 - Containers.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Containers. 113.60 Section 113.60 Food and Drugs... CONSUMPTION THERMALLY PROCESSED LOW-ACID FOODS PACKAGED IN HERMETICALLY SEALED CONTAINERS Control of Components, Food Product Containers, Closures, and In-Process Materials § 113.60 Containers. (a) Closures...

21 CFR 113.60 - Containers.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Containers. 113.60 Section 113.60 Food and Drugs... CONSUMPTION THERMALLY PROCESSED LOW-ACID FOODS PACKAGED IN HERMETICALLY SEALED CONTAINERS Control of Components, Food Product Containers, Closures, and In-Process Materials § 113.60 Containers. Link to an...

21 CFR 113.60 - Containers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Containers. 113.60 Section 113.60 Food and Drugs... CONSUMPTION THERMALLY PROCESSED LOW-ACID FOODS PACKAGED IN HERMETICALLY SEALED CONTAINERS Control of Components, Food Product Containers, Closures, and In-Process Materials § 113.60 Containers. (a) Closures...

18 CFR 401.113 - Segregable materials.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Segregable materials. 401.113 Section 401.113 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Public Access to Records and Information § 401.113...

46 CFR 113.37-1 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Applicability. 113.37-1 Section 113.37-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Shaft Speed and Thrust Indicators § 113.37-1 Applicability. This subpart applies to...

46 CFR 113.37-1 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Applicability. 113.37-1 Section 113.37-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Shaft Speed and Thrust Indicators § 113.37-1 Applicability. This subpart applies to...

46 CFR 113.37-10 - Detailed requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Detailed requirements. 113.37-10 Section 113.37-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Shaft Speed and Thrust Indicators § 113.37-10 Detailed requirements. (a...

46 CFR 113.37-10 - Detailed requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Detailed requirements. 113.37-10 Section 113.37-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Shaft Speed and Thrust Indicators § 113.37-10 Detailed requirements. (a...

14 CFR 13.113 - Noncompliance with the investigative process.

Code of Federal Regulations, 2010 CFR

2010-01-01

... process. 13.113 Section 13.113 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... an Order of Investigation § 13.113 Noncompliance with the investigative process. If any person fails... Officer or the designee of the Presiding Officer, judicial enforcement may be initiated against that...

High Level Expression and Purification of the Clinically Active Antimicrobial Peptide P-113 in Escherichia coli.

PubMed

Cheng, Kuang-Ting; Wu, Chih-Lung; Yip, Bak-Sau; Yu, Hui-Yuan; Cheng, Hsi-Tsung; Chih, Ya-Han; Cheng, Jya-Wei

2018-03-30

P-113, which was originally derived from the human saliva protein histatin 5, is a histidine-rich antimicrobial peptide with the sequence AKRHHGYKRKFH. P-113 is currently undergoing phase II clinical trial as a pharmaceutical agent to fight against fungal infections in HIV patients with oral candidiasis. Previously, we developed a new procedure for the high-yield expression and purification of hG31P, an analogue and antagonist of human CXCL8. Moreover, we have successfully removed lipopolysaccharide (LPS, endotoxin) associated with hG31P in the expression with Escherichia coli . In this paper, we have used hG31P as a novel fusion protein for the expression and purification of P-113. The purity of the expressed P-113 is more than 95% and the yield is 4 mg P-113 per liter of E. coli cell culture in Luria-Bertani (LB) medium. The antimicrobial activity of the purified P-113 was tested. Furthermore, we used circular dichroism (CD) and nuclear magnetic resonance (NMR) spectroscopy to study the structural properties of P-113. Our results indicate that using hG31P as a fusion protein to obtain large quantities of P-113 is feasible and is easy to scale up for commercial production. An effective way of producing enough P-113 for future clinical studies is evident in this study.

A Novel Soybean ERF Transcription Factor, GmERF113, Increases Resistance to Phytophthora sojae Infection in Soybean

PubMed Central

Zhao, Yuanling; Chang, Xin; Qi, Dongyue; Dong, Lidong; Wang, Guangjin; Fan, Sujie; Jiang, Liangyu; Cheng, Qun; Chen, Xi; Han, Dan; Xu, Pengfei; Zhang, Shuzhen

2017-01-01

Phytophthora root and stem rot of soybean caused by the oomycete Phytophthora sojae, is a destructive disease worldwide. Ethylene response factors (ERFs) play important roles in regulating plant biotic and abiotic stress tolerance. In this study, a new ERF gene, GmERF113, was isolated from the highly resistant soybean ‘Suinong 10.’ Sequence analysis suggested that the protein encoded by GmERF113 contained a conserved AP2/ERF domain of 58 amino acid and belonged to the B-4 subgroup of the ERF subfamily. Expression of GmERF113 was significantly induced by P. sojae, ethylene, and methyl jasmonate. GmERF113 protein localized to the nucleus when transiently expressed in Arabidopsis protoplasts, could bind to the GCC-box, and acted as a transcription activator. In addition, a region of the full-length GmERF113, GmERF113-II, interacted with a basic helix-loop-helix transcription factor (GmbHLH) in yeast cells. Full-length GmERF113 also interacted with GmbHLH in planta. GmERF113-overexpressing transgenic plants in susceptible cultivar ‘Dongnong 50’ soybean exhibited increased resistance to P. sojae and positively regulated the expression of the pathogenesis-related genes, PR1 and PR10-1. These results indicate that GmERF113 may play a crucial role in the defense of soybean against P. sojae infection. PMID:28326092

Early Cretaceous bimodal volcanism in the Duolong Cu mining district, western Tibet: Record of slab breakoff that triggered ca. 108-113 Ma magmatism in the western Qiangtang terrane

NASA Astrophysics Data System (ADS)

Wei, Shao-gang; Tang, Ju-xing; Song, Yang; Liu, Zhi-bo; Feng, Jun; Li, Yan-bo

2017-05-01

We report new zircon U-Pb ages and Hf isotope compositions, and whole-rock major and trace element and Sr-Nd isotope data for the Meiriqiecuo Formation (MF) bimodal volcanic rocks collected from the Duolong Cu mining district (DCMD) in the western Qiangtang terrane (QT), western Tibet. These data provide important constraints on the petrogenetic evolution and geodynamic setting of Early Cretaceous magmatism in the DCMD. The MF bimodal volcanic rocks are mainly basaltic andesite and andesite, with subordinate rhyolite. Four mafic samples yielded zircon U-Pb ages of ca. 108.2-113.0 Ma, and one silicic sample has an age of 109.3 ± 2.2 Ma, indicating that the mafic and silicic eruptions were contemporaneous. The MF bimodal volcanic rocks belong to the medium-K calc-alkaline to shoshonite series. The rocks show arc-type affinities characterized by significant enrichment in light rare earth (LaN/YbN = 7.74-12.60) and large-ion lithophile elements (Rb, Cs, K, and Pb), but depletions in the high-field-strength elements (Nb, Ta, and Ti), which geochemically resemble Andean arc basalts. Therefore, the MF bimodal volcanic rocks were likely emplaced at an Andean-type active continental margin and represent an Early Cretaceous magmatic arc that was located at the western QT margin. Moreover, the mafic volcanic rocks have high initial Sr isotopic ratios (0.705269-0.705413) and negative εNd(t) values of -1.5 to -0.6 compared with the silicic volcanic rocks ((87Sr/86Sr)i = 0.704770-0.704903; εNd(t) = +1.2 to +1.3). Zircons from silicic samples have significantly higher εHf(t) values (+11.6 to +15.5) and predominantly lower Paleoproterozoic Hf crustal model ages (TDMC = 180-428 Ma) than the mafic samples, which have variable εHf(t) values of +3.4 to +13.0 and TDMC ages of 346-952 Ma. These results indicate that the mafic and silicic end-members of the MF bimodal suite were generated from mantle and crustal sources, respectively. The basaltic andesite and andesite may have been derived from mantle enriched by the metasomatism of subducted fluids, whereas the rhyolite could have been derived by partial melting of mafic juvenile crust that originated from an older and more depleted mantle. In light of the geochemical characteristics and field relationships, we propose that breakoff of the Bangong-Nujiang oceanic lithosphere was responsible for the generation and emplacement of the MF bimodal volcanic rocks. The fact that the MF bimodal volcanic arc magmatism was active at ca. 108-113 Ma indicates that it was associated with closure of the Bangong-Nujiang Ocean via an arc-arc "soft" collision during the Early Cretaceous.

Construction and validation of a three-dimensional finite element model of degenerative scoliosis.

PubMed

Zheng, Jie; Yang, Yonghong; Lou, Shuliang; Zhang, Dongsheng; Liao, Shenghui

2015-12-24

With the aging of the population, degenerative scoliosis (DS) incidence rate is increasing. In recent years, increasing research on this topic has been carried out, yet biomechanical research on the subject is seldom seen and in vitro biomechanical model of DS nearly cannot be available. The objective of this study was to develop and validate a complete three-dimensional finite element model of DS in order to build the digital platform for further biomechanical study. A 55-year-old female DS patient (Suer Pan, ID number was P141986) was selected for this study. This study was performed in accordance with the ethical standards of Declaration of Helsinki and its amendments and was approved by the local ethics committee (117 hospital of PLA ethics committee). Spiral computed tomography (CT) scanning was conducted on the patient's lumbar spine from the T12 to S1. CT images were then imported into a finite element modeling system. A three-dimensional solid model was then formed from segmentation of the CT scan. The three-dimensional model of each vertebra was then meshed, and material properties were assigned to each element according to the pathological characteristics of DS. Loads and boundary conditions were then applied in such a manner as to simulate in vitro biomechanical experiments conducted on lumbar segments. The results of the model were then compared with experimental results in order to validate the model. An integral three-dimensional finite element model of DS was built successfully, consisting of 113,682 solid elements, 686 cable elements, 33,329 shell elements, 4968 target elements, 4968 contact elements, totaling 157,635 elements, and 197,374 nodes. The model accurately described the physical features of DS and was geometrically similar to the object of study. The results of analysis with the finite element model agreed closely with in vitro experiments, validating the accuracy of the model. The three-dimensional finite element model of DS built in this study is clear, reliable, and effective for further biomechanical simulation study of DS.

The influence of the Amazonian floodplain ecosystems on the trace element dynamics of the Amazon River mainstem (Brazil).

PubMed

Viers, Jérôme; Barroux, Guénaël; Pinelli, Marcello; Seyler, Patrick; Oliva, Priscia; Dupré, Bernard; Boaventura, Geraldo Resende

2005-03-01

The purpose of this paper is to forecast the role of riverine wetlands in the transfer of trace elements. One of the largest riverine wetlands in the world is the floodplain (várzea) of the Amazon River and its tributaries (Junk and Piedade, 1997). The central Amazon wetlands are constituted by a complex network of lakes and floodplains, named várzeas, that extend over more than 300,000 km2 (Junk, W.J., The Amazon floodplain--a sink or source for organic carbon? In Transport of Carbon and Minerals in Major World Rivers, edited by E.T. Degens, S. Kempe, R. Herrera, SCOPE/UNEP; 267-283, 1985.) and are among the most productive ecosystems in the world due to the regular enrichment in nutrients by river waters In order to understand if the adjacent floodplain of Amazon River have a significant influence on the trace element concentrations and fluxes of the mainstem, the concentrations of selected elements (i.e., Al, Mn, Fe, Co, Cu, Mo, Rb, Sr, Ba, and U) have been measured in the Amazon River water (Manacapuru Station, Amazonas State, Brazil) and in lake waters and plants (leaves) from a várzea(Ilha de Marchantaria, Amazonas State, Brazil) during different periods of the hydrological cycle. Four plant species (two perennial species: Pseudobombax munguba and Salix humboldtiana, and two annual herbaceous plants: Echinochloa polystachya and Eichhornia crassipes) were selected to represent the ecological functioning of the site. Time series obtained for dissolved Mn and Cu (<0.20 microm) in Amazon River water could not be explained by tributary mixing or instream processes only. Therefore, the contribution of the waters transiting the floodplains should be considered. These results suggest that the chemical composition of the waters draining these floodplains is controlled by reactions occurring at sediment-water and plant-water interfaces. Trace elements concentrations in the plants (leaves) vary strongly with hydrological seasonality. Based on the concentration data and the biological productivity of floodplain ecosystems, a first order approximation of trace element storage (permanent or temporary) in the vegetation of these floodplains was made. It was found that floodplain-mainstem elemental fluxes make a significant contribution to the dissolved flux of the Amazon River. This study is part of the Brazilian_French joint research program Hybam (Hydrology and Geochemistry of the Amazonian Basin).

46 CFR 113.10-5 - Common return.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Common return. 113.10-5 Section 113.10-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Fire and Smoke Detecting and Alarm Systems § 113.10-5 Common return. A conductor...

9 CFR 113.3 - Sampling of biological products.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Sampling of biological products. 113.3 Section 113.3 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... Applicability § 113.3 Sampling of biological products. Each licensee and permittee shall furnish representative...

9 CFR 113.3 - Sampling of biological products.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Sampling of biological products. 113.3 Section 113.3 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... Applicability § 113.3 Sampling of biological products. Each licensee and permittee shall furnish representative...

32 CFR 219.113 - Suspension or termination of IRB approval of research.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Suspension or termination of IRB approval of research. 219.113 Section 219.113 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PROTECTION OF HUMAN SUBJECTS § 219.113 Suspension or...

48 CFR 18.113 - Interagency acquisitions under the Economy Act.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Interagency acquisitions under the Economy Act. 18.113 Section 18.113 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES EMERGENCY ACQUISITIONS Available Acquisition Flexibilities 18.113 Interagency acquisitions under...

16 CFR 1028.113 - Suspension or termination of IRB approval of research.

Code of Federal Regulations, 2010 CFR

2010-01-01

... research. 1028.113 Section 1028.113 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL PROTECTION OF HUMAN SUBJECTS § 1028.113 Suspension or termination of IRB approval of research. An IRB shall... with the IRB's requirements or that has been associated with unexpected serious harm to subjects. Any...

46 CFR 113.30-5 - Requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Requirements. 113.30-5 Section 113.30-5 Shipping COAST... SYSTEMS AND EQUIPMENT Internal Communications § 113.30-5 Requirements. (a) Communication. Each vessel must... finder. Communication to the radio and radio direction finder must meet the following requirements: (1...

46 CFR 113.30-5 - Requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Requirements. 113.30-5 Section 113.30-5 Shipping COAST... SYSTEMS AND EQUIPMENT Internal Communications § 113.30-5 Requirements. (a) Communication. Each vessel must... finder. Communication to the radio and radio direction finder must meet the following requirements: (1...

46 CFR 113.30-5 - Requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Requirements. 113.30-5 Section 113.30-5 Shipping COAST... SYSTEMS AND EQUIPMENT Internal Communications § 113.30-5 Requirements. (a) Communication. Each vessel must... finder. Communication to the radio and radio direction finder must meet the following requirements: (1...

14 CFR 1215.113 - User charges.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false User charges. 1215.113 Section 1215.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION TRACKING AND DATA RELAY SATELLITE SYSTEM (TDRSS) Use and Reimbursement Policy for Non-U.S. Government Users § 1215.113 User charges. (a) The user...

14 CFR 1215.113 - User charges.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true User charges. 1215.113 Section 1215.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION TRACKING AND DATA RELAY SATELLITE SYSTEM (TDRSS) Use and Reimbursement Policy for Non-U.S. Government Users § 1215.113 User charges. (a) The user...

78 FR 56148 - Airworthiness Directives; Bell Helicopter Textron Canada Limited (Bell) Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-12

... Assembly Engine Bipod Mount, P/N 230-060-113-101, 230-060-113-102, 230-060-114-101, or 230-060-114-102... 430 with (i) Fitting Assembly Engine Bipod Mount, P/N 230-060-113-101, 230-060-113-102, 230-060-114...

6 CFR 11.3 - Demand for payment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 6 Domestic Security 1 2010-01-01 2010-01-01 false Demand for payment. 11.3 Section 11.3 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CLAIMS § 11.3 Demand for payment. (a) Notice requirements. Generally, before DHS starts the collection actions described in this subpart, DHS...

49 CFR 194.113 - Information summary.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 3 2013-10-01 2013-10-01 false Information summary. 194.113 Section 194.113... Response Plans § 194.113 Information summary. (a) The information summary for the core plan, required by... state(s). (b) The information summary for the response zone appendix, required in § 194.107, must...

46 CFR 16.113 - Chemical drug testing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Chemical drug testing. 16.113 Section 16.113 Shipping... General § 16.113 Chemical drug testing. (a) Drug testing programs required by this part must be conducted... should be consulted to determine the specific procedures which must be established and utilized. Drug...

46 CFR 16.113 - Chemical drug testing.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 1 2014-10-01 2014-10-01 false Chemical drug testing. 16.113 Section 16.113 Shipping... General § 16.113 Chemical drug testing. (a) Drug testing programs required by this part must be conducted... should be consulted to determine the specific procedures which must be established and utilized. Drug...

46 CFR 16.113 - Chemical drug testing.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Chemical drug testing. 16.113 Section 16.113 Shipping... General § 16.113 Chemical drug testing. (a) Drug testing programs required by this part must be conducted... should be consulted to determine the specific procedures which must be established and utilized. Drug...

46 CFR 16.113 - Chemical drug testing.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Chemical drug testing. 16.113 Section 16.113 Shipping... General § 16.113 Chemical drug testing. (a) Drug testing programs required by this part must be conducted... should be consulted to determine the specific procedures which must be established and utilized. Drug...

46 CFR 16.113 - Chemical drug testing.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Chemical drug testing. 16.113 Section 16.113 Shipping... General § 16.113 Chemical drug testing. (a) Drug testing programs required by this part must be conducted... should be consulted to determine the specific procedures which must be established and utilized. Drug...

46 CFR 113.25-6 - Power supply.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Power supply. 113.25-6 Section 113.25-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-6 Power supply. The emergency power source...

46 CFR 113.25-6 - Power supply.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Power supply. 113.25-6 Section 113.25-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-6 Power supply. The emergency power source...

46 CFR 113.43-5 - Power supply.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Power supply. 113.43-5 Section 113.43-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Steering Failure Alarm Systems § 113.43-5 Power supply. Each steering failure alarm...

46 CFR 113.43-5 - Power supply.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Power supply. 113.43-5 Section 113.43-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Steering Failure Alarm Systems § 113.43-5 Power supply. Each steering failure alarm...

46 CFR 113.25-6 - Power supply.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Power supply. 113.25-6 Section 113.25-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-6 Power supply. The emergency power source...

46 CFR 113.43-5 - Power supply.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Power supply. 113.43-5 Section 113.43-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Steering Failure Alarm Systems § 113.43-5 Power supply. Each steering failure alarm...

21 CFR 133.113 - Cheddar cheese.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Cheddar cheese. 133.113 Section 133.113 Food and... CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific Standardized Cheese and Related Products § 133.113 Cheddar cheese. (a) Description. (1) Cheddar cheese is the food prepared by the...

21 CFR 133.113 - Cheddar cheese.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Cheddar cheese. 133.113 Section 133.113 Food and... CONSUMPTION CHEESES AND RELATED CHEESE PRODUCTS Requirements for Specific Standardized Cheese and Related Products § 133.113 Cheddar cheese. (a) Description. (1) Cheddar cheese is the food prepared by the...

46 CFR 113.25-12 - Alarm signals.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Alarm signals. 113.25-12 Section 113.25-12 Shipping... SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-12 Alarm signals. (a) Each general emergency alarm signal must be an electrically-operated bell, klaxon, or other warning device capable of...

46 CFR 113.25-12 - Alarm signals.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Alarm signals. 113.25-12 Section 113.25-12 Shipping... SYSTEMS AND EQUIPMENT General Emergency Alarm Systems § 113.25-12 Alarm signals. (a) Each general emergency alarm signal must be an electrically-operated bell, klaxon, or other warning device capable of...

9 CFR 113.55 - Detection of extraneous agents in Master Seed Virus.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Master Seed Virus. 113.55 Section 113.55 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD REQUIREMENTS Ingredient Requirements § 113.55 Detection of extraneous agents in Master Seed Virus...