Tennessine Announced As Provisional Name For Superheavy Element 117

ScienceCinema

Roberto, Jim

2018-01-16

The International Union of Pure and Applied Chemistry (IUPAC) Inorganic Chemistry Division has published a Provisional Recommendation for the names and symbols of the recently discovered superheavy elements 113, 115, 117, and 118. Tennessine (Ts) is proposed for element 117, recognizing the contribution of Tennessee research centers ORNL, Vanderbilt and the University of Tennessee to superheavy element research.

49 CFR 240.115 - Criteria for consideration of prior safety conduct as a motor vehicle operator.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CERTIFICATION OF LOCOMOTIVE ENGINEERS Component Elements of the Certification Process § 240.115 Criteria for... occurred more than 36 months before the month in which the railroad is making its certification decision and shall only consider information concerning the following types of motor vehicle incidents: (1) A...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roberto, Jim

The International Union of Pure and Applied Chemistry (IUPAC) Inorganic Chemistry Division has published a Provisional Recommendation for the names and symbols of the recently discovered superheavy elements 113, 115, 117, and 118. Tennessine (Ts) is proposed for element 117, recognizing the contribution of Tennessee research centers ORNL, Vanderbilt and the University of Tennessee to superheavy element research.

Tunable Optical Sources.

DTIC Science & Technology

1980-11-01

finite aperture size 5. A. E. Siegman , "Unstable optical resonators for laser of the YAG rod, applications," Proc. IEEE 53, 217-287 (1965); "Unstable...Pumped LiNbO3 Tunable Source Radial Birefringent Element Computer Controlled Laser Attenuator Slab Configuration Laser Source 20. ABSTRACT (Continue on...have invented and demonstrated a computer controlled laser attenu- ator. .... Cont inued DD Il 7 1473 EDITION OF I NOV 01 IS OBSOLETE UNCLASSIFIEDAN

STS-115 Vitual Lab Training

NASA Image and Video Library

2005-06-07

JSC2005-E-21191 (7 June 2005) --- Astronaut Steven G. MacLean, STS-115 mission specialist representing the Canadian Space Agency, uses the virtual reality lab at the Johnson Space Center to train for his duties aboard the space shuttle. This type of computer interface, paired with virtual reality training hardware and software, helps to prepare the entire team for dealing with space station elements.

STS-115 Vitual Lab Training

NASA Image and Video Library

2005-06-07

JSC2005-E-21192 (7 June 2005) --- Astronauts Christopher J. Ferguson (left), STS-115 pilot, and Daniel C. Burbank, mission specialist, use the virtual reality lab at the Johnson Space Center to train for their duties aboard the space shuttle. This type of computer interface, paired with virtual reality training hardware and software, helps to prepare the entire team for dealing with space station elements.

Interaction of petroleum mulching, vegetation restoration and dust fallout on the conditions of sand dunes in southwest of Iran

NASA Astrophysics Data System (ADS)

Azoogh, Liela; Khalili moghadam, Bijan; Jafari, Siroos

2018-06-01

In the past half-century, petroleum mulching-biological fixation (PM-BF) practices have been employed to stabilize sand dunes in Iran. However, the effects of PM-BF practices on the attributes of sand dunes and the dispersion of heavy metals of mulch have been poorly understood. To this end, three regions treated with PM-BF for 5, 20, and 40 years and a control region with no PM-BF were studied. Samples of soil properties were taken at the depths of 0-10 cm and 10-50 cm, with three replications, in Khuzestan Province. The results showed that PM-BF practices promoted the restoration of vegetation cover in the sand dunes. In addition, these practices increased the deposition of dust particles, gradually increasing the magnitudes of palygorskite and smectite clays over time. The interactions between dust deposition and PM-BF practices significantly altered the chemical and physical properties of the dunes. PM-BF practices increased soil organic matter (184-287%), cation exchangeable capacity (142-209%), electrical conductivity (144-493%), clay content (134-196%), and penetration resistance (107-170%) compared to the region with no PM-BF practices. Furthermore, petroleum mulching significantly increased the amount of Ni (1.19%), Cd (1.55%), Pb (1.08%), Cu (1.34%), Zn (1.38%), Mn (1.66%), and Fe (1.15%). However, in the long term, these elements will probably leach linearly as a consequence of an increase in organic matter and soil salinity in the light texture of sand dunes.

20 CFR 404.287 - Waiver of recomputation.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Waiver of recomputation. 404.287 Section 404.287 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Computing Primary Insurance Amounts Recomputing Your Primary Insurance Amount § 404.287...

Focusing through the rib cage for MR-guided transcostal FUS

NASA Astrophysics Data System (ADS)

Gao, J.; Volovick, A.; Pekelny, Y.; Huang, ZH.; Cochran, S.; Melzer, A.

2012-10-01

The rib cage presents a significant obstacle in transcostal focused ultrasound surgery (FUS). This paper proposes a geometric solution, based on central projection from the focus to identify transducer elements affected by ribs shadowing which should be switched off. Its effectiveness in phantom experiments and simulations is reported, and ways are discussed to further reduce energy deposition on the ribs while enhancing heating at the focus. A tissue-mimicking phantom with phantom of ribs was sonicated using a 208-element 1.15 MHz bowl transducer and a 1000-element 550 kHz planar matrix transducer (both ExAblate, InSightec, Israel). The temperature evolution was monitored with real-time MRI thermometry (GE, USA). Numerical simulations were performed with FEA software (PZFlex, Weidlinger Associates, USA) to investigate different skin-focus and transducer-rib distances. The temperature rise near the ribs was reduced to 16°C and 4°C for the 1.15 MHz and 550 kHz transducers respectively. With the 1.15 MHz transducer, the focal temperature reached the ablation threshold. These measurements are in good agreement with simulations. The proposed method shows promising results for transcostal FUS. Residual temperature rise on the ribs can be further reduced by active cooling, allowing the higher energies essential for efficient ablation.

46 CFR 502.287 - Depositions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 9 2011-10-01 2011-10-01 false Depositions. 502.287 Section 502.287 Shipping FEDERAL... Investigations § 502.287 Depositions. The Commission, or its duly authorized representative, may order testimony to be taken by deposition in any investigation at any stage of such investigation. Such depositions...

46 CFR 502.287 - Depositions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 9 2010-10-01 2010-10-01 false Depositions. 502.287 Section 502.287 Shipping FEDERAL... Investigations § 502.287 Depositions. The Commission, or its duly authorized representative, may order testimony to be taken by deposition in any investigation at any stage of such investigation. Such depositions...

32 CFR 287.3 - Authority.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Authority. 287.3 Section 287.3 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY FREEDOM OF INFORMATION ACT PROGRAM § 287.3 Authority. This part...

32 CFR 287.9 - Reports.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 2 2012-07-01 2012-07-01 false Reports. 287.9 Section 287.9 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY FREEDOM OF INFORMATION ACT PROGRAM § 287.9 Reports. An annual...

32 CFR 287.7 - Fees.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Fees. 287.7 Section 287.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY FREEDOM OF INFORMATION ACT PROGRAM § 287.7 Fees. Fees charged...

46 CFR 287.20 - Obligation of deposits.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Obligation of deposits. 287.20 Section 287.20 Shipping... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.20 Obligation of deposits. (a) Time for obligation. Within three years from the date of any deposit in a construction reserve fund, unless extension...

8 CFR 287.9 - Criminal search warrant and firearms policies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Criminal search warrant and firearms policies. 287.9 Section 287.9 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS FIELD OFFICERS; POWERS AND DUTIES § 287.9 Criminal search warrant and firearms policies. (a) A...

46 CFR 287.11 - Time deposits.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 8 2014-10-01 2014-10-01 false Time deposits. 287.11 Section 287.11 Shipping MARITIME... OF CONSTRUCTION RESERVE FUNDS § 287.11 Time deposits. Deposits in the construction reserve fund not invested in securities may be placed in time deposits when, in the judgment of the taxpayer, it is...

46 CFR 287.11 - Time deposits.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 8 2012-10-01 2012-10-01 false Time deposits. 287.11 Section 287.11 Shipping MARITIME... OF CONSTRUCTION RESERVE FUNDS § 287.11 Time deposits. Deposits in the construction reserve fund not invested in securities may be placed in time deposits when, in the judgment of the taxpayer, it is...

46 CFR 287.11 - Time deposits.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 8 2011-10-01 2011-10-01 false Time deposits. 287.11 Section 287.11 Shipping MARITIME... OF CONSTRUCTION RESERVE FUNDS § 287.11 Time deposits. Deposits in the construction reserve fund not invested in securities may be placed in time deposits when, in the judgment of the taxpayer, it is...

46 CFR 287.11 - Time deposits.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 8 2013-10-01 2013-10-01 false Time deposits. 287.11 Section 287.11 Shipping MARITIME... OF CONSTRUCTION RESERVE FUNDS § 287.11 Time deposits. Deposits in the construction reserve fund not invested in securities may be placed in time deposits when, in the judgment of the taxpayer, it is...

46 CFR 287.8 - Investment of funds in securities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Investment of funds in securities. 287.8 Section 287.8... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.8 Investment of funds in securities. (a...), or securities which are not legal for investment of trust funds. Whenever the Administration approves...

46 CFR 287.8 - Investment of funds in securities.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 8 2011-10-01 2011-10-01 false Investment of funds in securities. 287.8 Section 287.8... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.8 Investment of funds in securities. (a...), or securities which are not legal for investment of trust funds. Whenever the Administration approves...

8 CFR 287.5 - Exercise of power by immigration officers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Exercise of power by immigration officers. 287.5 Section 287.5 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS FIELD OFFICERS; POWERS AND DUTIES § 287.5 Exercise of power by immigration officers. (a) Power and...

46 CFR 287.27 - Controlled corporation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 8 2014-10-01 2014-10-01 false Controlled corporation. 287.27 Section 287.27 Shipping... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.27 Controlled corporation. For the purpose of... acquired by a corporation at a time when the taxpayer owns not less than 95 percent of the total number of...

46 CFR 287.27 - Controlled corporation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 8 2011-10-01 2011-10-01 false Controlled corporation. 287.27 Section 287.27 Shipping... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.27 Controlled corporation. For the purpose of... acquired by a corporation at a time when the taxpayer owns not less than 95 percent of the total number of...

46 CFR 287.27 - Controlled corporation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 8 2013-10-01 2013-10-01 false Controlled corporation. 287.27 Section 287.27 Shipping... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.27 Controlled corporation. For the purpose of... acquired by a corporation at a time when the taxpayer owns not less than 95 percent of the total number of...

46 CFR 287.27 - Controlled corporation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Controlled corporation. 287.27 Section 287.27 Shipping... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.27 Controlled corporation. For the purpose of... acquired by a corporation at a time when the taxpayer owns not less than 95 percent of the total number of...

46 CFR 287.27 - Controlled corporation.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 8 2012-10-01 2012-10-01 false Controlled corporation. 287.27 Section 287.27 Shipping... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.27 Controlled corporation. For the purpose of... acquired by a corporation at a time when the taxpayer owns not less than 95 percent of the total number of...

8 CFR 287.3 - Disposition of cases of aliens arrested without warrant.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Disposition of cases of aliens arrested without warrant. 287.3 Section 287.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS FIELD OFFICERS; POWERS AND DUTIES § 287.3 Disposition of cases of aliens arrested without warrant...

42 CFR 137.287 - What is the National Environmental Policy Act (NEPA)?

Code of Federal Regulations, 2010 CFR

2010-10-01

...)? 137.287 Section 137.287 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction Nepa Process § 137.287 What is the National Environmental Policy Act (NEPA)? The NEPA is a procedural law that...

32 CFR 287.9 - Reports.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 2 2011-07-01 2011-07-01 false Reports. 287.9 Section 287.9 National Defense... PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY FREEDOM OF INFORMATION ACT PROGRAM § 287.9 Reports. An annual report will be furnished to the FOIA Officer by the field activities by 15 October IAW 32 CFR part 286. ...

32 CFR 287.9 - Reports.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Reports. 287.9 Section 287.9 National Defense... PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY FREEDOM OF INFORMATION ACT PROGRAM § 287.9 Reports. An annual report will be furnished to the FOIA Officer by the field activities by 15 October IAW 32 CFR part 286. ...

32 CFR 287.9 - Reports.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Reports. 287.9 Section 287.9 National Defense... PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY FREEDOM OF INFORMATION ACT PROGRAM § 287.9 Reports. An annual report will be furnished to the FOIA Officer by the field activities by 15 October IAW 32 CFR part 286. ...

32 CFR 287.9 - Reports.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 2 2013-07-01 2013-07-01 false Reports. 287.9 Section 287.9 National Defense... PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY FREEDOM OF INFORMATION ACT PROGRAM § 287.9 Reports. An annual report will be furnished to the FOIA Officer by the field activities by 15 October IAW 32 CFR part 286. ...

Archaeological Investigations at Sites 45-OK-287 and 45-OK-288, Chief Joseph Dam Project, Washington.

DTIC Science & Technology

1984-01-01

Table C-1. Distribution of butchering marks and evidence of burning by element .. ....... ....... ....... .. 258 xvii9. LIST OF PLATES Plate 1-1. 45-OK...the vicinity of the Omak Trench. Till forms the terrace on which the site Is located, and glaclolacustrIne sediments of two ! -ages exposed In the...the site were exposed In fewer excavation units, but they have a finer grain size and greater proportion of angular cobbles, deriving from the bedrock

45 CFR 287.45 - How can NEW Program funds be used?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false How can NEW Program funds be used? 287.45 Section 287.45 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE... EMPLOYMENT WORKS (NEW) PROGRAM NEW Program Funding § 287.45 How can NEW Program funds be used? (a) NEW grants...

45 CFR 287.125 - What supportive and job retention services may be provided under the NEW Program?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false What supportive and job retention services may be provided under the NEW Program? 287.125 Section 287.125 Public Welfare Regulations Relating to Public... Operations § 287.125 What supportive and job retention services may be provided under the NEW Program? The...

Finite Element Method of Stress Analysis of Nonaxisymmetric Configurations

DTIC Science & Technology

1980-04-01

UC(3*(KK-1)+I+12) = B(3*NP2-3+I) 110 CONTINUE DO 115 KK=1,24 115 UT(KK) = FfG(KK+(NS-1)»12) WRITE(6,900) 900 FORMAT(" "," EL SIGMAR SIGMAZ...1,12) 126 WHiT£(6,200i) T(N),(£PS(I),I=1,12) 200 CONTINUE 2000 FORMAT(129H1 EL fi Z SIGMAR SIGMAZ 3IGMAC SiGMA 1RZ SiGMAZC SIGMACH

Challenges Facing ZnO and GaN: Facts and Myths. Held in Glen Allen, Virginia on 18-19 October 2007

DTIC Science & Technology

2007-10-01

115 4 VIII.4.3.1. Improving dopant solubility........................................................... 115 VIII.4.3.2. Designing shallow defect...possible (e.g., ZnMgO grown at AFRL-Hanscom). intentional doping •Boron and aluminum only suspected n-type dopants detected (red) •Nitrogen...and sodium as only possible p-type dopants detected (blue) •The major impurity consistently present is silicon (from the quartz ampoule) •Elements

Methylation of Arsenic by Recombinant Human Wild-Type Arsenic (+3 Oxidation State) Methyltransferase and its Methionine 287 Threonine (M287T) Polymorph

EPA Science Inventory

ABSTRACT Arsenic (+3 oxidation state) methyltransferase (AS3MT) is the key enzyme in the pathway for methylation of arsenicals. A common polymorphism in the AS3MT gene that replaces a threonyl residue in position 287 with a methionyl residue (AS3MT/M287T) occurs at a frequency...

Testing a Model of Diabetes Self-Care Management: A Causal Model Analysis with LISREL.

ERIC Educational Resources Information Center

Nowacek, George A.; And Others

1990-01-01

A diabetes-management model is presented, which includes an attitudinal element and depicts relationships among causal elements. LISREL-VI was used to analyze data from 115 Type-I and 105 Type-II patients. The data did not closely fit the model. Results support the importance of the personal meaning of diabetes. (TJH)

Angiotensin-converting enzyme gene insertion/deletion polymorphism studies in Asian Indian pregnant women biochemically identifies gestational diabetes mellitus.

PubMed

Khan, Imran A; Jahan, Parveen; Hasan, Qurratulain; Rao, Pragna

2014-12-01

Gestational diabetes mellitus (GDM) is defined as glucose intolerance first recognized during pregnancy. Insertion/deletion (I/D) polymorphism of a 287 bp Alu repetitive sequence in intron 16 of the angiotensin-converting enzyme (ACE) gene has been widely investigated in Asian Indian populations with different ethnic origins. The present study examined possible association between I/D polymorphism of the ACE gene and GDM in Asian Indian pregnant women. A total of 200 pregnant women (100 GDM and 100 non-GDM) were recruited in this study and I/D polymorphism of a 287 bp Alu1 element inside intron 16 of the ACE gene was examined by polymerase chain reaction (PCR)-based gel electrophoresis. The distribution of the variants like II, ID, and DD genotypes of ACE gene showed differences between normal GDM versus non-GDM subjects, and the frequency of the ID+ DD Vs II genotype was significant (p=0.0002) in the GDM group. ACE gene polymorphism was associated with GDM in Asian Indian pregnant women. © The Author(s) 2013.

Survival-mediated capture and fusion cross sections for heavy-element synthesis

NASA Astrophysics Data System (ADS)

Yao, L.; Loveland, W.

2018-01-01

The cross section for producing a heavy evaporation residue σEVR in a fusion reaction can be written as a product of three nonseparable factors, i.e., the capture cross section, the fusion probability PCN, and the survival probability Wsur. Each of these factors is dependent on the spin. However, one must remember that the Wsur term is zero or very small for higher spin values, thus effectively limiting the capture and fusion terms. For a series of ˜287 reactions leading to heavy evaporation residues with ZCN≤110 , we point out the implications of this fact for capture cross sections for heavy element formation reactions. From a comparison of calculated and measured evaporation residue cross sections we deduce values of the fusion probability PCN for some of these reactions.

[Metabolic disorders and adiposity in a rural population].

PubMed

Silva, Daniele A; Felisbino-Mendes, Mariana S; Pimenta, Adriano M; Gazzinelli, Andrea; Kac, Gilberto; Velásquez-Meléndez, Gustavo

2008-04-01

The aim of this cross-sectional study was to verify the prevalence of overweight and central adiposity (CA) in a sample of 287 adult subjects that lived in a rural community of Minas Gerais State. Means lipids, lipoproteins, glucose and blood pressure levels were compared according adiposity categories using One-way ANOVA and Tukey tests. Prevalence of overweight was 24.8% (37.4% for female; 11.5% for male). CA was verified in 28.1% of the individuals (50.3% for female; 4.3% for male). The associations between CA and overweight with the metabolic disorders: arterial hypertension (AH), dyslipidemia and hyperglycemia were estimated. Subjects with CA presented higher mean values of blood pressure, total cholesterol, LDL, triglycerides, fasting glucose, and lower mean values of HDL. CA was associated with AH, dyslipidemia and hyperglycemia. Associations between overweight and AH, dyslipidemia and hyperglycemia were also verified. These results confirm the potential effect of body composition shifting, especially at the abdominal level, on lipids, glucose metabolism and on blood pressure levels in rural populations.

Head injury and loss of consciousness raise the likelihood of developing and maintaining PTSD symptoms.

PubMed

Roitman, Pablo; Gilad, Moran; Ankri, Yahel L E; Shalev, Arieh Y

2013-12-01

Mild traumatic brain injury has been associated with higher prevalence of posttraumatic stress disorder (PTSD). The extent to which head injury or loss of consciousness predicts PTSD is unknown. To evaluate the contribution of head injury and loss of consciousness to the occurrence of PTSD, we made a longitudinal evaluation of 1,260 road accident survivors admitted to the emergency department with head injury (n = 287), head injury and loss of consciousness (n = 115), or neither (n = 858). A telephone-administered posttraumatic symptoms scale inferred PTSD and quantified PTSD symptoms at 10 days and 8 months after admission. The study groups had similar heart rate, blood pressure, and pain levels in the emergency department. Survivors with loss of consciousness and head injury had higher prevalence of PTSD and higher levels of PTSD symptoms, suggesting that patients with head injury and loss of consciousness reported in the emergency department are at higher risk for PTSD. Copyright © 2013 International Society for Traumatic Stress Studies.

32 CFR 287.2 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Applicability. This part applies to DISA and the Office of the Manager, National Communications System (OMNCS). ... 32 National Defense 2 2012-07-01 2012-07-01 false Applicability. 287.2 Section 287.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF...

32 CFR 287.2 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Applicability. This part applies to DISA and the Office of the Manager, National Communications System (OMNCS). ... 32 National Defense 2 2013-07-01 2013-07-01 false Applicability. 287.2 Section 287.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF...

32 CFR 287.2 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Applicability. This part applies to DISA and the Office of the Manager, National Communications System (OMNCS). ... 32 National Defense 2 2010-07-01 2010-07-01 false Applicability. 287.2 Section 287.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF...

32 CFR 287.2 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Applicability. This part applies to DISA and the Office of the Manager, National Communications System (OMNCS). ... 32 National Defense 2 2011-07-01 2011-07-01 false Applicability. 287.2 Section 287.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF...

32 CFR 287.2 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Applicability. This part applies to DISA and the Office of the Manager, National Communications System (OMNCS). ... 32 National Defense 2 2014-07-01 2014-07-01 false Applicability. 287.2 Section 287.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF...

42 CFR 137.287 - What is the National Environmental Policy Act (NEPA)?

Code of Federal Regulations, 2014 CFR

2014-10-01

...: categorical exclusions, environmental assessments, and environmental impact statements. ... 42 Public Health 1 2014-10-01 2014-10-01 false What is the National Environmental Policy Act (NEPA)? 137.287 Section 137.287 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

42 CFR 137.287 - What is the National Environmental Policy Act (NEPA)?

Code of Federal Regulations, 2011 CFR

2011-10-01

...: categorical exclusions, environmental assessments, and environmental impact statements. ... 42 Public Health 1 2011-10-01 2011-10-01 false What is the National Environmental Policy Act (NEPA)? 137.287 Section 137.287 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

42 CFR 137.287 - What is the National Environmental Policy Act (NEPA)?

Code of Federal Regulations, 2013 CFR

2013-10-01

...: categorical exclusions, environmental assessments, and environmental impact statements. ... 42 Public Health 1 2013-10-01 2013-10-01 false What is the National Environmental Policy Act (NEPA)? 137.287 Section 137.287 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

42 CFR 137.287 - What is the National Environmental Policy Act (NEPA)?

Code of Federal Regulations, 2012 CFR

2012-10-01

...: categorical exclusions, environmental assessments, and environmental impact statements. ... 42 Public Health 1 2012-10-01 2012-10-01 false What is the National Environmental Policy Act (NEPA)? 137.287 Section 137.287 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

45 CFR 287.80 - What is the process for plan review and approval?

Code of Federal Regulations, 2010 CFR

2010-10-01

... Division of Tribal Services, Office of Community Services, Administration for Children and Families...? 287.80 Section 287.80 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN...

17 CFR 287.2 - Periodic reports.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Periodic reports. 287.2 Section 287.2 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A to Part 285 GENERAL RULES AND REGULATIONS PURSUANT TO SECTION 11(a) OF THE ASIAN DEVELOPMENT BANK ACT...

17 CFR 287.2 - Periodic reports.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Periodic reports. 287.2 Section 287.2 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A to Part 285 GENERAL RULES AND REGULATIONS PURSUANT TO SECTION 11(a) OF THE ASIAN DEVELOPMENT BANK ACT...

17 CFR 287.2 - Periodic reports.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Periodic reports. 287.2 Section 287.2 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A to Part 285 GENERAL RULES AND REGULATIONS PURSUANT TO SECTION 11(a) OF THE ASIAN DEVELOPMENT BANK ACT...

17 CFR 287.2 - Periodic reports.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Periodic reports. 287.2 Section 287.2 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A to Part 285 GENERAL RULES AND REGULATIONS PURSUANT TO SECTION 11(a) OF THE ASIAN DEVELOPMENT BANK ACT...

17 CFR 287.2 - Periodic reports.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Periodic reports. 287.2 Section 287.2 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A to Part 285 GENERAL RULES AND REGULATIONS PURSUANT TO SECTION 11(a) OF THE ASIAN DEVELOPMENT BANK ACT...

8 CFR 287.6 - Proof of official records.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Proof of official records. 287.6 Section 287.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS FIELD OFFICERS... certificates recording the registration of a document or the fact that it was in existence on a certain date...

8 CFR 287.6 - Proof of official records.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Proof of official records. 287.6 Section 287.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS FIELD OFFICERS... certificates recording the registration of a document or the fact that it was in existence on a certain date...

8 CFR 287.6 - Proof of official records.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Proof of official records. 287.6 Section 287.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS FIELD OFFICERS... certificates recording the registration of a document or the fact that it was in existence on a certain date...

8 CFR 287.6 - Proof of official records.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Proof of official records. 287.6 Section 287.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS FIELD OFFICERS... certificates recording the registration of a document or the fact that it was in existence on a certain date...

15 CFR 287.2 - Definitions. 1

Code of Federal Regulations, 2013 CFR

2013-01-01

... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Definitions. 1 287.2 Section 287.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF... respect to the food industry sector. Accreditation means a procedure used to provide formal notice that a...

15 CFR 287.2 - Definitions. 1

Code of Federal Regulations, 2014 CFR

2014-01-01

... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Definitions. 1 287.2 Section 287.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF... respect to the food industry sector. Accreditation means a procedure used to provide formal notice that a...

15 CFR 287.2 - Definitions. 1

Code of Federal Regulations, 2012 CFR

2012-01-01

... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Definitions. 1 287.2 Section 287.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF... respect to the food industry sector. Accreditation means a procedure used to provide formal notice that a...

45 CFR 287.120 - What work activities may be provided under the NEW Program?

Code of Federal Regulations, 2013 CFR

2013-10-01

... Program? 287.120 Section 287.120 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN..., alternative education, post secondary education, job readiness activity, job search, job skills training...

45 CFR 287.120 - What work activities may be provided under the NEW Program?

Code of Federal Regulations, 2014 CFR

2014-10-01

... Program? 287.120 Section 287.120 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN..., alternative education, post secondary education, job readiness activity, job search, job skills training...

45 CFR 287.120 - What work activities may be provided under the NEW Program?

Code of Federal Regulations, 2012 CFR

2012-10-01

... Program? 287.120 Section 287.120 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN..., alternative education, post secondary education, job readiness activity, job search, job skills training...

32 CFR 287.8 - Appeal rights.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Appeal rights. 287.8 Section 287.8 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF... rights. All appeals should be addressed to the Director, DISA, and be postmarked no later than 60 days...

8 CFR 287.2 - Disposition of criminal cases.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Disposition of criminal cases. 287.2... OFFICERS; POWERS AND DUTIES § 287.2 Disposition of criminal cases. Whenever a special agent in charge, port... criminal provision of the immigration and nationality laws administered or enforced by the Department, he...

17 CFR 287.4 - Preparation and filing of reports.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Preparation and filing of reports. 287.4 Section 287.4 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A to Part 285 GENERAL RULES AND REGULATIONS PURSUANT TO SECTION 11(a) OF THE ASIAN...

17 CFR 287.4 - Preparation and filing of reports.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Preparation and filing of reports. 287.4 Section 287.4 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A to Part 285 GENERAL RULES AND REGULATIONS PURSUANT TO SECTION 11(a) OF THE ASIAN...

17 CFR 287.4 - Preparation and filing of reports.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Preparation and filing of reports. 287.4 Section 287.4 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A to Part 285 GENERAL RULES AND REGULATIONS PURSUANT TO SECTION 11(a) OF THE ASIAN...

17 CFR 287.4 - Preparation and filing of reports.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Preparation and filing of reports. 287.4 Section 287.4 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A to Part 285 GENERAL RULES AND REGULATIONS PURSUANT TO SECTION 11(a) OF THE ASIAN...

15 CFR 287.3 - Responsibilities of the National Institute of Standards and Technology.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Institute of Standards and Technology. 287.3 Section 287.3 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE... National Institute of Standards and Technology. (a) Work with agencies through the Interagency Committee on...

18 CFR 287.101 - Determination of powerplant design capacity.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Determination of powerplant design capacity. 287.101 Section 287.101 Conservation of Power and Water Resources FEDERAL ENERGY... generator's kilovolt-amperes nameplate rating and power factor nameplate rating. (b) Combustion turbine. The...

18 CFR 287.101 - Determination of powerplant design capacity.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Determination of powerplant design capacity. 287.101 Section 287.101 Conservation of Power and Water Resources FEDERAL ENERGY... generator's kilovolt-amperes nameplate rating and power factor nameplate rating. (b) Combustion turbine. The...

18 CFR 287.101 - Determination of powerplant design capacity.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Determination of powerplant design capacity. 287.101 Section 287.101 Conservation of Power and Water Resources FEDERAL ENERGY... generator's kilovolt-amperes nameplate rating and power factor nameplate rating. (b) Combustion turbine. The...

18 CFR 287.101 - Determination of powerplant design capacity.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Determination of powerplant design capacity. 287.101 Section 287.101 Conservation of Power and Water Resources FEDERAL ENERGY... generator's kilovolt-amperes nameplate rating and power factor nameplate rating. (b) Combustion turbine. The...

18 CFR 287.101 - Determination of powerplant design capacity.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Determination of powerplant design capacity. 287.101 Section 287.101 Conservation of Power and Water Resources FEDERAL ENERGY... generator's kilovolt-amperes nameplate rating and power factor nameplate rating. (b) Combustion turbine. The...

Uranium-lead systematics of low-Ti basaltic meteorite Dhofar 287A: Affinity to Apollo 15 green glasses

NASA Astrophysics Data System (ADS)

Terada, Kentaro; Sasaki, Yu; Anand, Mahesh; Sano, Yuji; Taylor, Lawrence A.; Horie, Kenji

2008-06-01

Dhofar 287 is a lunar meteorite found in Oman in 2001, which consists of a major portion (95%) of low-Ti mare basalt (Dho 287A) and a minor attached part (˜ 5%) of regolith breccia (Dho 287B). Here, we report the U-Pb systematics of Dho 287A using data collected with a Sensitive High Resolution Ion Microprobe (SHRIMP). In-situ analyses of five merrillite and three apatite grains, which are resistant to secondary petrologic events, resulted in a total Pb/U isochron age of 3.34 ± 0.20 Ga, in 238U/206Pb-207Pb/206Pb-204Pb/206Pb 3-D space (95% confidence level). The observed Pb-Pb isochron of these eight phosphates coupled with four plagioclase grains also yielded a 207Pb/206Pb age of 3.35 ± 0.13 Ga. This formation age, when considered as the crystallization age of Dho 287A, is similar to crystallization ages of Apollo 15 low-Ti olivine-normative basalts (ONB; 3.3 ± 0.1 Ga). However, the estimated μ-value (238U/204Pb ratio) of Dho 287A is ˜ 18, which is very different from the reported μ-values of ˜ 300 for mare basalts from the Apollo collections, including the Apollo 15 ONBs. These μ-values are still significantly lower than those of Apollo KREEP basalt (500 to 1000), although a possible assimilation with KREEP has been previously proposed for Dho 287A using geochemical criteria. Our U-Pb study of Dho 287A, instead, indicates a closer affinity to Apollo 15 green glasses (207Pb/206Pb age of 3.41 Ga with μ-value of 19 to 55), which are considered to be the most primitive products of lunar volcanism. Combining our U-Pb data with the previously reported Sm-Nd systematics (negative ɛNd) of Dho 287A clearly distinguishes this meteorite from those of the Yamato 793169 and Asuka 88175 group which have extremely low μ-value of 10-22, old crystallization ages of 3.9 Ga, and high positive ɛNd, suggesting that Dho 287A may be a representative of an entirely new group of mare basalt derived from previously unsampled source region on the Moon.

Evaluation of Populus and Salix continuously irrigated with landfill leachate II. soils and early tree development.

PubMed

Zalesny, Ronald S; Bauer, Edmund O

2007-01-01

Soil contaminant levels and early tree growth data are helpful for assessing phytoremediation systems. Populus (DN17, DN182, DN34, NM2, and NM6) and Salix (94003, 94012, S287, S566, and SX61) genotypes were irrigated with landfill leachate or municipal water and tested for differences in (1) element concentrations (P, K, Ca, Mg, S, Zn, B, Mn, Fe, Cu, Al, and Na) of a topsoil layer and a layer of sand in tanks with a cover crop of trees or no trees and (2) height, diameter, volume, and dry mass of leaves, stems, and roots. Trees were irrigated with leachate or water during the final 12 wk of the 18-wk study. Differences in most soil element concentrations were negligible (P > 0.05) for irrigation treatments and cover main effects. Phosphorous, K, Mg, S, Zn, Mn, Fe, and Al concentrations were greater in topsoil than sand (P = 0.0011 for Mg; P < 0.0001 for others). There was broad variation between genera and among clones for all growth traits. The treatment x clone interaction governed height, volume, and root dry mass, with (94012, SX61), (NM2, S566, SX61), and (S287, S566) exhibiting the greatest levels, respectively,following leachate application. Given the broad amount of variability among and within these genera, there is great potential for the identification and selection of specific genotypes with a combination of elevated phytoremediation capabilities and tree yield. From a practical standpoint, these results may be used as a baseline for the development of future remediation systems.

Production and isolation of homologs of flerovium and element 115 at the Lawrence Livermore National Laboratory Center for Accelerator Mass Spectrometry

DOE PAGES

Despotopulos, John D.; Kmak, Kelly N.; Gharibyan, Narek; ...

2015-10-01

Here, new procedures have been developed to isolate no-carrier-added (NCA) radionuclides of the homologs and pseudo-homologs of flerovium (Hg, Sn) and element 115 (Sb), produced by 12–15 MeV proton irradiation of foil stacks with the tandem Van-de-Graaff accelerator at the Lawrence Livermore National Laboratory Center for Accelerator Mass Spectrometry (CAMS) facility. The separation of 113Sn from natIn foil was performed with anion-exchange chromatography from hydrochloric and nitric acid matrices. A cation-exchange chromatography method based on hydrochloric and mixed hydrochloric/hydroiodic acids was used to separate 124Sb from natSn foil. A procedure using Eichrom TEVA resin was developed to separate 197Hg frommore » Au foil. These results demonstrate the suitability of using the CAMS facility to produce NCA radioisotopes for studies of transactinide homologs.« less

45 CFR 287.35 - What grant amounts are available under the Personal Responsibility and Work Opportunity...

Code of Federal Regulations, 2010 CFR

2010-10-01

... NATIVE EMPLOYMENT WORKS (NEW) PROGRAM NEW Program Funding § 287.35 What grant amounts are available under the Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (PRWORA) for the NEW... Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (PRWORA) for the NEW Program? 287...

45 CFR 287.145 - What measures will be used to determine NEW Program outcomes?

Code of Federal Regulations, 2010 CFR

2010-10-01

... Program outcomes? 287.145 Section 287.145 Public Welfare Regulations Relating to Public Welfare OFFICE OF... What measures will be used to determine NEW Program outcomes? Each grantee must develop its own... must identify planned program outcomes and the measures the Tribe will use to determine them. ACF will...

76 FR 63346 - Environmental Impact Statement, Tappan Zee Bridge/I-287 Corridor Project (Rockland and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-12

... Environmental Impact Statement, Tappan Zee Bridge/I-287 Corridor Project (Rockland and Westchester Counties, New... an Environmental Impact Statement (EIS) for the proposed Tappan Zee Bridge/I-287 Corridor project... Port Chester, Westchester County, New York including the Tappan Zee Bridge over the Hudson River. The...

Sequences required for induction of neurotensin receptor gene expression during neuronal differentiation of N1E-115 neuroblastoma cells.

PubMed

Tavares, D; Tully, K; Dobner, P R

1999-10-15

The promoter region of the mouse high affinity neurotensin receptor (Ntr-1) gene was characterized, and sequences required for expression in neuroblastoma cell lines that express high affinity NT-binding sites were characterized. Me(2)SO-induced neuronal differentiation of N1E-115 neuroblastoma cells increased both the expression of the endogenous Ntr-1 gene and reporter genes driven by NTR-1 promoter sequences by 3-4-fold. Deletion analysis revealed that an 83-base pair promoter region containing the transcriptional start site is required for Me(2)SO activation. Detailed mutational analysis of this region revealed that a CACCC box and the central region of a large GC-rich palindrome are the crucial cis-regulatory elements required for Me(2)SO induction. The CACCC box is bound by at least one factor that is induced upon Me(2)SO treatment of N1E-115 cells. The Me(2)SO effect was found to be both selective and cell type-restricted. Basal expression in the neuroblastoma cell lines required a distinct set of sequences, including an Sp1-like sequence, and a sequence resembling an NGFI-A-binding site; however, a more distal 5' sequence was found to repress basal activity in N1E-115 cells. These results provide evidence that Ntr-1 gene regulation involves both positive and negative regulatory elements located in the 5'-flanking region and that Ntr-1 gene activation involves the coordinate activation or induction of several factors, including a CACCC box binding complex.

Effects of protectant and rehydration conditions on the survival rate and malolactic fermentation efficiency of freeze-dried Lactobacillus plantarum JH287.

PubMed

Lee, Sae-Byuk; Kim, Dong-Hwan; Park, Heui-Dong

2016-09-01

In this study, Lactobacillus plantarum JH287 was used as a malolactic fermentation starter in Campbell Early wine production. L. plantarum JH287 was first lyophilized, and the malolactic fermentation potential of freeze-dried L. plantarum JH287 was investigated. Different protective media and rehydration conditions were tested to improve the survival rate of freeze-dried L. plantarum JH287. Optimal protective medium contained 10 % sorbitol and 10 % skim milk. The optimal rehydration condition was a 1-h rehydration time conducted in the same protective media, and the combination of these two methods produced a survival rate of 86.37 %. In addition, a 77.71 % survival rate was achieved using freeze-dried samples that were stored at 4 °C for 2 months. Freeze-dried L. plantarum JH287 and Saccharomyces cerevisiae Fermivin were used to inoculate the Campbell Early grape must to decrease its malic acid content. Using this mixed-fermentation method, wine showed a decrease in malic acid content after 9 days of fermentation. GC-MS analysis detected 15 volatile ester compounds in the wine. A sensory evaluation showed that the taste and aroma of mix-fermented wine were better than those of the control that had not been inoculated with L. plantarum JH287.

8 CFR 287.5 - Exercise of power by immigration officers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Exercise of power by immigration officers... FIELD OFFICERS; POWERS AND DUTIES § 287.5 Exercise of power by immigration officers. (a) Power and... to exercise anywhere in or outside the United States the power conferred by: (1) Section 287(a)(1) of...

8 CFR 287.5 - Exercise of power by immigration officers.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Exercise of power by immigration officers... FIELD OFFICERS; POWERS AND DUTIES § 287.5 Exercise of power by immigration officers. (a) Power and... to exercise anywhere in or outside the United States the power conferred by: (1) Section 287(a)(1) of...

8 CFR 287.5 - Exercise of power by immigration officers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Exercise of power by immigration officers... FIELD OFFICERS; POWERS AND DUTIES § 287.5 Exercise of power by immigration officers. (a) Power and... to exercise anywhere in or outside the United States the power conferred by: (1) Section 287(a)(1) of...

45 CFR 287.105 - What provisions of the Social Security Act govern the NEW Program?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false What provisions of the Social Security Act govern the NEW Program? 287.105 Section 287.105 Public Welfare Regulations Relating to Public Welfare OFFICE....105 What provisions of the Social Security Act govern the NEW Program? NEW Programs are subject only...

32 CFR 287.11 - “For Official Use Only” Records.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false âFor Official Use Onlyâ Records. 287.11 Section... PROGRAM § 287.11 “For Official Use Only” Records. The designation “For Official Use Only” will be applied... may be obtained via Internet at http://web7.whs.osd.mil/corres.htm. ...

45 CFR 287.105 - What provisions of the Social Security Act govern the NEW Program?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 2 2014-10-01 2012-10-01 true What provisions of the Social Security Act govern the NEW Program? 287.105 Section 287.105 Public Welfare Regulations Relating to Public Welfare OFFICE....105 What provisions of the Social Security Act govern the NEW Program? NEW Programs are subject only...

45 CFR 287.140 - With whom should the Tribe coordinate in the operation of its work activities and services?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 2 2014-10-01 2012-10-01 true With whom should the Tribe coordinate in the operation of its work activities and services? 287.140 Section 287.140 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND...

45 CFR 287.105 - What provisions of the Social Security Act govern the NEW Program?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true What provisions of the Social Security Act govern the NEW Program? 287.105 Section 287.105 Public Welfare Regulations Relating to Public Welfare OFFICE....105 What provisions of the Social Security Act govern the NEW Program? NEW Programs are subject only...

45 CFR 287.140 - With whom should the Tribe coordinate in the operation of its work activities and services?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false With whom should the Tribe coordinate in the operation of its work activities and services? 287.140 Section 287.140 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND...

45 CFR 287.105 - What provisions of the Social Security Act govern the NEW Program?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 2 2012-10-01 2012-10-01 false What provisions of the Social Security Act govern the NEW Program? 287.105 Section 287.105 Public Welfare Regulations Relating to Public Welfare OFFICE....105 What provisions of the Social Security Act govern the NEW Program? NEW Programs are subject only...

49 CFR 192.287 - Plastic pipe: Inspection of joints.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 3 2011-10-01 2011-10-01 false Plastic pipe: Inspection of joints. 192.287... Than by Welding § 192.287 Plastic pipe: Inspection of joints. No person may carry out the inspection of joints in plastic pipes required by §§ 192.273(c) and 192.285(b) unless that person has been qualified by...

45 CFR 287.105 - What provisions of the Social Security Act govern the NEW Program?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false What provisions of the Social Security Act govern the NEW Program? 287.105 Section 287.105 Public Welfare Regulations Relating to Public Welfare OFFICE....105 What provisions of the Social Security Act govern the NEW Program? NEW Programs are subject only...

49 CFR 192.287 - Plastic pipe: Inspection of joints.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 3 2014-10-01 2014-10-01 false Plastic pipe: Inspection of joints. 192.287... Than by Welding § 192.287 Plastic pipe: Inspection of joints. No person may carry out the inspection of joints in plastic pipes required by §§ 192.273(c) and 192.285(b) unless that person has been qualified by...

49 CFR 192.287 - Plastic pipe: Inspection of joints.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 3 2012-10-01 2012-10-01 false Plastic pipe: Inspection of joints. 192.287... Than by Welding § 192.287 Plastic pipe: Inspection of joints. No person may carry out the inspection of joints in plastic pipes required by §§ 192.273(c) and 192.285(b) unless that person has been qualified by...

49 CFR 192.287 - Plastic pipe: Inspection of joints.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 3 2013-10-01 2013-10-01 false Plastic pipe: Inspection of joints. 192.287... Than by Welding § 192.287 Plastic pipe: Inspection of joints. No person may carry out the inspection of joints in plastic pipes required by §§ 192.273(c) and 192.285(b) unless that person has been qualified by...

METHYLATION OF ARSENIC BY RECOMBINANT HUMAN AS3MT/287M AND AS3MT/287T POLYMORPHS

EPA Science Inventory

Arsenic (+3 oxidation state) methyltransferase (AS3MT) is the key enzyme in the pathway for methylation of inorganic arsenic (iAs). AS3MT polymorphism is, in part, responsible for interindividual differences in iAs metabolism. AS3MT/M287T polymorphism that is found in ~ 10% of C...

Safety and immunogenicity of a freeze-dried, Vero cell culture-derived, inactivated Japanese encephalitis vaccine (KD-287, ENCEVAC®) versus a mouse brain-derived inactivated Japanese encephalitis vaccine in children: a phase III, multicenter, double-blinded, randomized trial.

PubMed

Yun, Ki Wook; Lee, Hoan Jong; Kang, Jin Han; Eun, Byung Wook; Kim, Yae-Jean; Kim, Kyung-Hyo; Kim, Nam Hee; Hong, Young Jin; Kim, Dong Ho; Kim, Hwang Min; Cha, Sung-Ho

2015-01-08

Although mouse brain-derived, inactivated Japanese encephalitis vaccines (JE-MBs) have been successfully used for a long time, potential rare neurological complications have prompted the development of a Vero cell culture-derived inactivated vaccine (JE-VC). In a phase III clinical study, we aimed to compare the safety and immunogenicity of a JE-VC, KD-287 with a JE-MB, JEV-GCC, in children. In this multicenter, double-blinded, randomized controlled trial, the study population consisted of 205 healthy Korean children aged 12-23 months. Each subject was subcutaneously vaccinated with either KD-287 or JEV-GCC twice at an interval of 2 weeks and then vaccinated once 12 months after the second vaccination. Neutralizing antibodies were measured by the plaque reduction neutralization test using the homologous and heterologous, as a post hoc analysis, challenge virus strains. The three-dose regimen of KD-287 showed a comparable safety profile with JEV-GCC except higher incidence of fever after the first dose (30.4% and 14.7%, respectively). Most of the fever was mild degree (61.3% and 66.7%, respectively). KD-287 fulfilled the non-inferiority criteria for seroconversion rate (SCR) and geometric mean titer (GMT) of the neutralizing antibody, which were the primary endpoints, at 4 weeks after the third vaccination (95% CI: -1.00, 3.10 for the SCR difference and 10.8, 17.6 for the GMT ratio). The SCRs of KD-287 were all 100% and the GMTs were higher in the KD-287 group than in the JEV-GCC group after the second vaccination and before and after the third vaccination (GMT ratio: 5.59, 20.13, and 13.79, respectively, p < 0.001 in all). GMTs were higher in the KD-287 group in the heterologous analysis also (GMT ratio: 4.05, 5.15, and 4.19, respectively, p < 0.001 in all). This study suggests that the KD-287, a JE-VC is as safe as and may be more effective than the licensed MB-derived vaccine. KD-287 could thus be useful as a second-generation vaccine and substitute for the current JE-MB vaccine in Korean children. ClinicalTrials.gov: NCT01150942.

Altered Methylation in Tandem Repeat Element and Elemental Component Levels in Inhalable Air Particles

PubMed Central

Hou, Lifang; Zhang, Xiao; Zheng, Yinan; Wang, Sheng; Dou, Chang; Guo, Liqiong; Byun, Hyang-Min; Motta, Valeria; McCracken, John; Díaz, Anaité; Kang, Choong-Min; Koutrakis, Petros; Bertazzi, Pier Alberto; Li, Jingyun; Schwartz, Joel; Baccarelli, Andrea A.

2014-01-01

Exposure to particulate matter (PM) has been associated with lung cancer risk in epidemiology investigations. Elemental components of PM have been suggested to have critical roles in PM toxicity, but the molecular mechanisms underlying their association with cancer risks remain poorly understood. DNA methylation has emerged as a promising biomarker for environmental-related diseases, including lung cancer. In this study, we evaluated the effects of PM elemental components on methylation of three tandem repeats in a highly-exposed population in Beijing, China. The Beijing Truck Driver Air Pollution Study was conducted shortly before the 2008 Beijing Olympic Games (June 15-July 27, 2008) and included 60 truck drivers and 60 office workers. On two days separated by 1-2 weeks, we measured blood DNA methylation of SATα, NBL2, D4Z4, and personal exposure to eight elemental components in PM2.5, including aluminum (Al), silicon (Si), sulfur (S), potassium (K), calcium (Ca) titanium (Ti), iron (Fe), and zinc (Zn). We estimated the associations of individual elemental component with each tandem repeat methylation in generalized estimating equations (GEE) models adjusted for PM2.5 mass and other covariates. Out of the eight examined elements, NBL2 methylation was positively associated with concentrations of Si (0.121, 95%CI: 0.030; 0.212, FDR=0.047) and Ca (0.065, 95%CI: 0.014; 0.115, FDR=0.047) in truck drivers. In office workers, SATα methylation was positively associated with concentrations of S (0.115, 95%CI: 0.034; 0.196, FDR=0.042). PM-associated differences in blood tandem-repeat methylation may help detect biological effects of the exposure and identify individuals who may eventually experience higher lung cancer risk. PMID:24273195

32 CFR 287.6 - Duties of the DITCO and the DTIC FOIA officers.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 2 2011-07-01 2011-07-01 false Duties of the DITCO and the DTIC FOIA officers... INFORMATION ACT PROGRAM § 287.6 Duties of the DITCO and the DTIC FOIA officers. (a) DITCO FOIA Officer. The... duties stated in § 287.4 (d) and (h). (b) DTIC FOIA Officer. The DTIC FOIA Officer, located at 8725 John...

32 CFR 287.6 - Duties of the DITCO and the DTIC FOIA officers.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 2 2013-07-01 2013-07-01 false Duties of the DITCO and the DTIC FOIA officers... INFORMATION ACT PROGRAM § 287.6 Duties of the DITCO and the DTIC FOIA officers. (a) DITCO FOIA Officer. The... duties stated in § 287.4 (d) and (h). (b) DTIC FOIA Officer. The DTIC FOIA Officer, located at 8725 John...

32 CFR 287.6 - Duties of the DITCO and the DTIC FOIA officers.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Duties of the DITCO and the DTIC FOIA officers... INFORMATION ACT PROGRAM § 287.6 Duties of the DITCO and the DTIC FOIA officers. (a) DITCO FOIA Officer. The... duties stated in § 287.4 (d) and (h). (b) DTIC FOIA Officer. The DTIC FOIA Officer, located at 8725 John...

32 CFR 287.6 - Duties of the DITCO and the DTIC FOIA officers.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 2 2012-07-01 2012-07-01 false Duties of the DITCO and the DTIC FOIA officers... INFORMATION ACT PROGRAM § 287.6 Duties of the DITCO and the DTIC FOIA officers. (a) DITCO FOIA Officer. The... duties stated in § 287.4 (d) and (h). (b) DTIC FOIA Officer. The DTIC FOIA Officer, located at 8725 John...

49 CFR 40.287 - What information is an employer required to provide concerning SAP services to an employee who...

Code of Federal Regulations, 2010 CFR

2010-10-01

... provide concerning SAP services to an employee who has a DOT drug and alcohol regulation violation? 40.287... § 40.287 What information is an employer required to provide concerning SAP services to an employee who... (including an applicant or new employee) who violates a DOT drug and alcohol regulation a listing of SAPs...

Methylation of arsenic by recombinant human wild-type arsenic (+ 3 oxidation state) methyltransferase and its methionine 287 threonine (M287T) polymorph: Role of glutathione

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ding, Lan; Saunders, R. Jesse; Drobná, Zuzana

2012-10-01

Arsenic (+ 3 oxidation state) methyltransferase (AS3MT) is the key enzyme in the pathway for methylation of arsenicals. A common polymorphism in the AS3MT gene that replaces a threonyl residue in position 287 with a methionyl residue (AS3MT/M287T) occurs at a frequency of about 10% among populations worldwide. Here, we compared catalytic properties of recombinant human wild-type (wt) AS3MT and AS3MT/M287T in reaction mixtures containing S-adenosylmethionine, arsenite (iAs{sup III}) or methylarsonous acid (MAs{sup III}) as substrates and endogenous or synthetic reductants, including glutathione (GSH), a thioredoxin reductase (TR)/thioredoxin (Trx)/NADPH reducing system, or tris (2-carboxyethyl) phosphine hydrochloride (TCEP). With either TR/Trx/NADPHmore » or TCEP, wtAS3MT or AS3MT/M287T catalyzed conversion of iAs{sup III} to MAs{sup III}, methylarsonic acid (MAs{sup V}), dimethylarsinous acid (DMAs{sup III}), and dimethylarsinic acid (DMAs{sup V}); MAs{sup III} was converted to DMAs{sup III} and DMAs{sup V}. Although neither enzyme required GSH to support methylation of iAs{sup III} or MAs{sup III}, addition of 1 mM GSH decreased K{sub m} and increased V{sub max} estimates for either substrate in reaction mixtures containing TR/Trx/NADPH. Without GSH, V{sub max} and K{sub m} values were significantly lower for AS3MT/M287T than for wtAS3MT. In the presence of 1 mM GSH, significantly more DMAs{sup III} was produced from iAs{sup III} in reactions catalyzed by the M287T variant than in wtAS3MT-catalyzed reactions. Thus, 1 mM GSH modulates AS3MT activity, increasing both methylation rates and yield of DMAs{sup III}. AS3MT genotype exemplified by differences in regulation of wtAS3MT and AS3MT/M287T-catalyzed reactions by GSH may contribute to differences in the phenotype for arsenic methylation and, ultimately, to differences in the disease susceptibility in individuals chronically exposed to inorganic arsenic. -- Highlights: ► Human AS3MT and AS3MT(M287T) require a dithiol reductant for optimal activity. ► Both enzymes methylate arsenite to tri- and pentavalent methylated metabolites. ► Neither enzyme requires glutathione (GSH) to methylate arsenite or methylarsonite. ► However, in presence of a dithiol addition of 1 mM GSH increases methylation rates. ► In presence of 1 mM GSH, AS3MT(M287T) produces more dimethylarsinite than AS3MT.« less

Up-regulation of Jun/AP-1 during differentiation of N1E-115 neuroblastoma cells.

PubMed

de Groot, R P; Kruijer, W

1991-12-01

Neuroblastoma cell lines isolated from neuroblastoma tumors can be induced to differentiate into neuronal cell types by treatment with chemical agents, such as dimethyl sulfoxide and retinoic acid. The molecular mechanisms underlying this differentiation process, however, are completely obscure. In this paper, we show that neuronal differentiation of mouse N1E-115 neuroblastoma cells by dimethyl sulfoxide is accompanied by a prolonged rise in c-jun, junB, and junD expression and AP-1 activity. Multiple sequence elements in the Jun promoters are involved in this process. Furthermore, we show that c-jun and junD, but not junB, are expressed at high levels in the neuronal cell types obtained after dimethyl sulfoxide treatment. These results suggest an important role for c-jun and junD in neuronal differentiation of N1E-115 cells.

[Novel Anticancer Strategy Targeting Switch Mechanisms in Two Types of Cell Death: Necrosis and Apoptosis].

PubMed

Sato, Akira

2017-01-01

 Two types of cell death, necrosis and apoptosis, are defined in terms of cell death morphological features. We have been studying the mechanisms by which cell death processes are switched during the treatment of mouse tumor FM3A with anticancer, 5-fluoro-2'-deoxyuridine (FUdR): it induces original clone F28-7 to necrosis, but its sub-clone F28-7-A to apoptosis. We identified several such switch regulators of cell death: heat shock protein 90 (HSP90), lamin-B1, cytokeratin-19, and activating transcription factor 3 (ATF3), by using transcriptomic, proteomic analyses and siRNA screening. For example, the inhibition of HSP90 by its inhibitor geldanamycin in F28-7 caused a shift from necrosis to apoptosis. We also observed that the knockdown of lamin-B1, cytokeratin-19, or ATF3 expression in F28-7 resulted in a shift from necrosis to apoptosis. Recently, we used microRNA (miRNA, miR) microarray analyses to investigate the miRNA expression profiles in these sister cells. The miR-351 and miR-743a were expressed at higher levels in F28-7-A than in F28-7. Higher expression of miR-351 or miR-743a in F28-7, induced by transfecting the miR mimics, resulted in a switch of cell death mode: necrosis to apoptosis. Furthermore, transfection of an miR-351 inhibitor into F28-7-A resulted in morphological changes, and mode of cell death from apoptosis to necrosis. These findings suggest that the identified cell death regulators may have key roles in switching cell death mode. Possible mechanisms involving cell death regulators in the switch of necrosis or apoptosis are discussed. We propose a novel anticancer strategy targeting the switch regulators of necrosis or apoptosis.

CRITICAL ELEMENTS IN DESCRIBING AND UNDERSTANDING OUR NATION'S AQUATIC RESOURCES

EPA Science Inventory

Despite spending $115 billion per year on environmental actions in the United States, we have only a limited ability to describe the effectiveness of these expenditures. Moreover, after decades of such investments, we cannot accurately describe status and trends in the nation's a...

40 CFR 35.115 - Evaluation of performance.

Code of Federal Regulations, 2010 CFR

2010-07-01

... requirements for progress reporting under 40 CFR 31.40(b). (b) Elements of the evaluation process. The.... The recipient may request review of the Regional Administrator's decision under the dispute processes... Evaluation of performance. (a) Joint evaluation process. The applicant and the Regional Administrator will...

76 FR 46807 - Agency Information Collection Activities: Announcement of Board Approval Under Delegated...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-03

... collections are mandatory. FR 2030 and FR 2030a: (12 U.S.C. 222, 282, 248(a) and 321). FR 2056: (12 U.S.C. 287, 248(a) and (i)). FR 2086: (12 U.S.C. 287, 248(a) and (i)). FR 2086a: (12 U.S.C. 321, 287, 248(a)). FR... to obtain a benefit (12 U.S.C. 338a, and 12 CFR 208.22). Individual respondent data generally are not...

Highly conserved D-loop-like nuclear mitochondrial sequences (Numts) in tiger (Panthera tigris).

PubMed

Zhang, Wenping; Zhang, Zhihe; Shen, Fujun; Hou, Rong; Lv, Xiaoping; Yue, Bisong

2006-08-01

Using oligonucleotide primers designed to match hypervariable segments I (HVS-1) of Panthera tigris mitochondrial DNA (mtDNA), we amplified two different PCR products (500 bp and 287 bp) in the tiger (Panthera tigris), but got only one PCR product (287 bp) in the leopard (Panthera pardus). Sequence analyses indicated that the sequence of 287 bp was a D-loop-like nuclear mitochondrial sequence (Numts), indicating a nuclear transfer that occurred approximately 4.8-17 million years ago in the tiger and 4.6-16 million years ago in the leopard. Although the mtDNA D-loop sequence has a rapid rate of evolution, the 287-bp Numts are highly conserved; they are nearly identical in tiger subspecies and only 1.742% different between tiger and leopard. Thus, such sequences represent molecular 'fossils' that can shed light on evolution of the mitochondrial genome and may be the most appropriate outgroup for phylogenetic analysis. This is also proved by comparing the phylogenetic trees reconstructed using the D-loop sequence of snow leopard and the 287-bp Numts as outgroup.

Subclinical hypothyroidism is associated with increased risk for cancer mortality in adult Taiwanese-a 10 years population-based cohort.

PubMed

Tseng, Fen-Yu; Lin, Wen-Yuan; Li, Chia-Ing; Li, Tsai-Chung; Lin, Cheng-Chieh; Huang, Kuo-Chin

2015-01-01

The association between subclinical hypothyroidism (SCH) and cancer mortality is seldom discussed. A total of 115,746 participants without thyroid disease history, aged 20 and above, were recruited from four nationwide health screening centers in Taiwan from 1998 to 1999. SCH was defined as a serum thyroid-stimulating hormone (TSH) level of 5.0-19.96 mIU/L with normal total thyroxine concentrations. Euthyroidism was defined as a serum TSH level of 0.47-4.9 mIU/L. Cox proportional hazards regression analyses were used to estimate the relative risks (RRs) of death from cancer for adults with SCH during a 10-year follow-up period. Among 115,746 adults, 1,841 had SCH (1.6%) and 113,905 (98.4%) had euthyroidism. There were 1,532 cancer deaths during the 1,034,082 person-years follow-up period. Adjusted for age, gender, body mass index, diabetes, hypertension, dyslipidemia, smoking, alcohol drinking, betel nut chewing, physical activity, income, and education level, the RRs (95% confidence interval) of cancer deaths among subjects with SCH versus euthyroid subjects were 1.51 (1.06 to 2.15). Cancer site analysis revealed a significant increased risk of bone, skin and breast cancer among SCH subjects (RR 2.79, (1.01, 7.70)). The risks of total cancer deaths were more prominent in the aged (RR 1.71, (1.02 to 2.87)), in females (RR 1.69 (1.08 to 2.65)), and in heavy smokers (RR 2.24, (1.19 to 4.21)). Subjects with SCH had a significantly increased risk for cancer mortality among adult Taiwanese. This is the first report to demonstrate the association between SCH and cancer mortality.

Waterpipe and Cigarette Smoking Among College Athletes in the United States

PubMed Central

Primack, Brian A.; Fertman, Carl I.; Rice, Kristen R.; Adachi-Mejia, Anna M.; Fine, Michael J.

2010-01-01

Purpose Tobacco use using a waterpipe is an emerging trend among college students. Although cigarette smoking is low among college athletes, waterpipe tobacco smoking may appeal to this population. The purpose of this study was to compare cigarette and waterpipe tobacco smoking in terms of their associations with organized sport participation. Methods In the spring of 2008, we conducted an online survey of 8,745 college students at eight institutions as part of the revised National College Health Assessment. We used multivariable regression models to assess the associations between tobacco use (cigarette and waterpipe) and organized sports participation. Results Participants reported participation in varsity (5.2%), club (11.9%), and intramural (24.9%) athletics. Varsity athletes and individuals who were not varsity athletes had similar rates of waterpipe tobacco smoking (27.6% vs. 29.5%, p = .41). However, other types of athletes were more likely than their counterparts to have smoked waterpipe tobacco (35.1% vs. 28.7%, p < .001 for club sports and 34.8% vs. 27.7%, p < .001 for intramural sports). In fully-adjusted multivariable models, sports participants of any type had lower odds of having smoked cigarettes, whereas participants who played intramural sports (odds ratio = 1.15, 95% confidence interval = 1.03, 1.29) or club sports (odds ratio = 1.15, 95% confidence interval = 1.001, 1.33) had significantly higher odds of having smoked waterpipe tobacco. Conclusions College athletes are susceptible to waterpipe tobacco use. In fact, compared with their nonathletic counterparts, club sports participants and intramural sports participants generally had higher odds of waterpipe tobacco smoking. Allure for waterpipe tobacco smoking may exist even for individuals who are traditionally considered at low risk for tobacco use. PMID:20123257

Comparison of jet Mach number decay data with a correlation and jet spreading contours for a large variety of nozzles

NASA Technical Reports Server (NTRS)

Groesbeck, D. E.; Huff, R. G.; Vonglahn, U. H.

1977-01-01

Small-scale circular, noncircular, single- and multi-element nozzles with flow areas as large as 122 sq cm were tested with cold airflow at exit Mach numbers from 0.28 to 1.15. The effects of multi-element nozzle shape and element spacing on jet Mach number decay were studied in an effort to reduce the noise caused by jet impingement on externally blown flap (EBF) STOL aircraft. The jet Mach number decay data are well represented by empirical relations. Jet spreading and Mach number decay contours are presented for all configurations tested.

Paleozoic mafic-intermediate intrusions (320-287 Ma) in the Kalatongke area, southern Altai, NW China: Products of protracted magmatism in a convergent tectonic setting

NASA Astrophysics Data System (ADS)

Qian, Zhuangzhi; Duan, Jun; Li, Chusi; Xu, Gang; Feng, Yanqing; Ren, Meng

2018-06-01

Numerous small mafic-intermediate intrusions are present in the Kalatongke area in the southern part of the Paleozoic Altai Orogenic Belt, NW China. Previous studies reveal that most of these intrusions were emplaced at ∼287 Ma, broadly coeval with the eruption of alkaline flood basalts at ⩽282 Ma in the Tarim Craton. The similar ages have led some researchers to believe that the Tarim flood basalts and the Kalatongke mafic-intermediate intrusions are related to the same mantle plume. New and existing geochronological and geochemical data for the mafic-intermediate intrusions in the Kalatongke area together do not support such interpretation. Most of the intrusions in this small area (4.5 × 2 km) were emplaced at ∼287 Ma but our new data reveal that older intrusive rocks with zircon U-Pb ages from 290 ± 1.5 to 320 ± 2 Ma are also present. The temporal and spatial distribution of these intrusions does not show a hotspot track as expected by the mantle plume model. The intrusive rocks have similar Nd-Hf isotope compositions (εNd = 3-9, εHf = 15-19) and are all characterized by light REE enrichments relative to heavy REE, plus pronounced negative Nb-Ta anomalies. The oldest intrusion (∼320 Ma) also shows negative Zr-Hf anomalies, which are common in arc basalts but absent in continental flood basalts. The results of mixing calculations based on Sr-Nd-Hf isotopes and selected trace elements (Th, Nb and Yb) indicate that the parental magmas for these intrusions were all enriched in Th and depleted in Nb prior to crustal contamination, similar to the magmas generated in a convergent tectonic setting from subduction to post-subduction elsewhere in the world. The results from this study remind us that temporal correlation is not a reliable tool to determine the size of a mantle plume.

45 CFR 287.90 - Are Tribes required to complete any certifications?

Code of Federal Regulations, 2010 CFR

2010-10-01

... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Plan Requirements § 287.90 Are Tribes required to...; Certification Regarding Drug Free Workplace Requirements for Grantees Other Than Individuals; Certification...

Orbit of the OJ287 black hole binary as determined from the General Relativity centenary flare

NASA Astrophysics Data System (ADS)

Valtonen, Mauri; Gopakumar, Achamveedu; Mikkola, Seppo; Zola, Staszek; Ciprini, Stefano; Matsumoto, Katsura; Sadakane, Kozo; Kidger, Mark; Gazeas, Kosmas; Nilsson, Kari; Berdyugin, Andrei; Piirola, Vilppu; Jermak, Helen; Baliyan, Kiran; Hudec, Rene; Reichart, Daniel

2016-05-01

OJ287 goes through large optical flares twice each 12 years. The times of these flares have been predicted successfully now 5 times using a black hole binary model. In this model a secondary black hole goes around a primary black hole, impacting the accretion disk of the latter twice per orbital period, creating a thermal flare. Together with 6 flares from the historical data base, the set of flare timings determines uniquely the 7 parameters of the model: the two masses, the primary spin, the major axis, eccentricity and the phase of the orbit, plus a time delay parameter that gives the extent of time between accretion disk impacts and the related optical flares. Based on observations by the OJ287-15/16 Collaboration, OJ287 went into the phase of rapid flux rise on November 25, on the centenary of Einstein’s General Relativity, and peaked on December 5. At that time OJ287 was the brightest in over 30 years in optical wavelengths. The flare was of low polarization, and did not extend beyond the optical/UV region of the spectrum. On top of the main flare there were a number of small flares; their excess brightness correlates well with the simultaneous X-ray data. With these properties the main flare qualifies as the marker of the orbit of the secondary going around the primary black hole. Since the orbit solution is strongly over-determined, its parameters are known very accurately, at better than one percent level for the masses and the spin. The next flare is predicted to peak on July 28, 2019.Detailed monitoring of this event should allow us to test, for the first time, the celebrated black hole no-hair theorem for a massive black hole at the 10% level. The present data is consistent with the theorem only at a 30% level. The main difficulty in observing OJ287 from Earth at our predicted epoch is its closeness to the sun. Therefore, it is desirable to monitor OJ287 from a space-based telescope not in the vicinity of Earth. Unfortunately, this unique opportunity for testing the above celebrated theorem of General Relativity using OJ287 will not be available again until after several orbital cycles.The full list of participants in the OJ287-15/16 Collaboration is found in ApJL 819, L37, 2016.

Studies of BL Lacertae objects with the Einstein Observatory - The soft X-ray spectra of OJ 287 and PKS 0735+178

NASA Technical Reports Server (NTRS)

Madejski, Greg M.; Schwartz, Daniel A.

1988-01-01

Accurate, soft X-ray spectra of two BL Lac objects, OJ 287 and PKS 0735+178, are presented. The X-ray spectra are well described by a power-law model with a low-energy cutoff consistent with photoelectric absorption within the Galaxy. The best-fit values of the energy spectral index in the 0.2-4.0 keV band are 0.91 and 0.76 respectively. The X-ray flux from OJ 287 is variable by a ratio of three from low to high state; PKS 0735+178 shows no indication of X-ray variability. The X-ray emission in OJ 287 is interpreted to be due to the synchrotron process from a volume common with either a beamed radio component or a stationary optical component. In PKS 0735+178, where the X-ray emission is most likely due to the Compton process operating in one of the VLBI radio components. The synchrotron self-Compton process with modest kinematic Doppler factors predicts the measured X-ray flux from PKS 0735+178 and lower than the measured flux in OJ 287.

Studies of flerovium and element 115 homologs with macrocyclic extractants

NASA Astrophysics Data System (ADS)

Despotopulos, John Dustin

Study of the chemistry of the heaviest elements, Z ? 104, poses a unique challenge due to their low production cross-sections and short half-lives. Chemistry also must be studied on the one-atom-at-a-time scale, requiring automated, fast, and very efficient chemical schemes. Recent studies of the chemical behavior of copernicium (Cn, element 112) and flerovium (Fl, element 114) together with the discovery of isotopes of these elements with half-lives suitable for chemical studies have spurred a renewed interest in the development of rapid systems designed to study the chemical properties of elements with Z ≥ 114. This dissertation explores both extraction chromatography and solvent extraction as methods for development of a rapid chemical separation scheme for the homologs of flerovium (Pb, Sn, Hg) and element 115 (Bi, Sb), with the goal of developing a chemical scheme that, in the future, can be applied to on-line chemistry of both Fl and element 115. Macrocyclic extractants, specifically crown ethers and their derivatives, were chosen for these studies. Carrier-free radionuclides, used in these studies, of the homologs of Fl and element 115 were obtained by proton activation of high purity metal foils at the Lawrence Livermore National Laboratory (LLNL) Center for Accelerator Mass Spectrometry (CAMS): natIn(p,n)113Sn, natSn(p,n)124Sb, and Au(p,n)197m,gHg. The carrier-free activity was separated from the foils by novel separation schemes based on ion exchange and extraction chromatography techniques. Carrier-free Pb and Bi isotopes were obtained from development of a novel generator based on cation exchange chromatography using the 232U parent to generate 212Pb and 212Bi. Crown ethers show high selectivity for metal ions based on their size compared to the negatively charged cavity of the ether. Extraction by crown ethers occur based on electrostatic ion-dipole interactions between the negatively charged ring atoms (oxygen, sulfur, etc.) and the positively charged metal cations. Extraction chromatography resins produced by Eichrom Technologies, specifically the Pb resin based on di-t-byutlcyclohexano-18-crown-6, were chosen as a starting point for these studies. Simple chemical systems based solely on HCl matrices were explored to determine the extent of extraction for Pb, Sn and Hg on the resin. The kinetics and mechanism of extraction were also explored to determine suitability for a Fl chemical experiment. Systems based on KI/HCl and KI/HNO3 were explored for Bi and Sb. In both cases suitable separations, with high separation factors, were performed with vacuum flow columns containing the Pb-resin. Unfortunately the kinetics of uptake for Hg are far too slow on the traditional crown-ether to perform a Fl experiment and obtain whether or not Fl has true Hg-like character or not. However, the kinetics of Pb and Sn are more than sufficient for a Fl experiment to differentiate between Pb- or Sn-like character. To assess this kinetic issue a novel macrocyclic extractant based on sulfur donors was synthesized. Hexathia-18-crown-6, the sulfur analog of 18-crown-6, was synthesized based with by a template reaction using high dilution techniques. The replacement of oxygen ring atoms with sulfur should give the extractant a softer character, which should allow for far greater affinity toward soft metals such as Hg and Pb. From HCl matrices hexathia-18-crown-6 showed far greater kinetics and affinity for Hg than the Pb-resin; however, no affinity for Pb or Sn was seen. This presumably is due to the fact the charge density of sulfur crown ethers does not point to the center of the ring, and future synthesis of a substituted sulfur crown ether which forces the charge density to mimic that of the traditional crown ether should enable extraction of Pb and Sn to a greater extent than with the Pb-resin. Initial studies show promise for the separation of Bi and Sb from HCl matrices using hexathia-18-crown-6. Other macrocyclic extractants, including 2,2,2-cryptand, calix[6]arene and tetrathia-12-crown-4, were also investigated for comparison to the crown ethers. It was noted that these extractants are inferior compared to the crown and thiacrown ethers for extraction of Fl and element 115 homologs. A potential chemical system for Fl was established based on the Eichrom Pb resin, and insight to an improved system based on thiacrown ethers is presented.

Simultaneous linear and circular polarization observations of blazars 3C 66A, OJ 287 and Markarian 421

NASA Astrophysics Data System (ADS)

Takalo, Leo O.; Sillanpaa, Aimo

1993-08-01

We present the first ever simultaneous optical linear and circular polarization observations of blazars. These polarizations have been measured simultaneously in UBVRI-bands in three blazars; 3C 66A, OJ 287 and Markarian 421. Measured linear polarization in 3C 66A was the largest ever observed, at PR equals 33.1 plus/minus .5%. In 3C 66A we detected small circular polarization on the other bands, except U. In OJ 287 we detected variable circular polarization in the U-band.

Atomic Mass and Nuclear Binding Energy for U-287 (Uranium)

NASA Astrophysics Data System (ADS)

Sukhoruchkin, S. I.; Soroko, Z. N.

This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope U-287 (Uranium, atomic number Z = 92, mass number A = 287).

Galaxy Evolution

NASA Astrophysics Data System (ADS)

Matteucci, F.

We review both the observational and theoretical constraints on the evolution of the abundances of heavy elements in gas and stars in galaxies of different morphological type. The main aim of this work is to document the progress made in our understanding of the physical processes regulating the chemical evolution of galaxies during the last sixteen years since the appearance, in this same journal (volume 5, page 287), of the well know review of Beatrice Tinsley, to whom I dedicate this paper. Finally, this article is addressed particularly to readers who do not actively work on galactic chemical evolution and who might use it as a cook book where the main ingredients are discussed and useful recipes can be found.

Convergence of microbial assimilations of soil carbon, nitrogen, phosphorus, and sulfur in terrestrial ecosystems

DOE PAGES

Xu, Xiaofeng; Hui, Dafeng; King, Anthony Wayne; ...

2015-11-27

How soil microbes assimilate carbon-C, nitrogen-N, phosphorus-P, and sulfur-S is fundamental for understanding nutrient cycling in terrestrial ecosystems. We compiled a global database of C, N, P, and S concentrations in soils and microbes and developed relationships between them by using a power function model. The C:N:P:S was estimated to be 287:17:1:0.8 for soils, and 42:6:1:0.4 for microbes. We found a convergence of the relationships between elements in soils and in soil microbial biomass across C, N, P, and S. The element concentrations in soil microbial biomass follow a homeostatic regulation curve with soil element concentrations across C, N, Pmore » and S, implying a unifying mechanism of microbial assimilating soil elements. This correlation explains the well-constrained C:N:P:S stoichiometry with a slightly larger variation in soils than in microbial biomass. Meanwhile, it is estimated that the minimum requirements of soil elements for soil microbes are 0.8 mmol C Kg –1 dry soil, 0.1 mmol N Kg –1 dry soil, 0.1 mmol P Kg –1 dry soil, and 0.1 mmol S Kg –1 dry soil, respectively. Lastly, these findings provide a mathematical explanation of element imbalance in soils and soil microbial biomass, and offer insights for incorporating microbial contribution to nutrient cycling into Earth system models.« less

NSWC Library of Mathematics Subroutines

DTIC Science & Technology

1990-01-01

sufficiently many zero elements for it to be worthwhile to use special techniques that avoid storing and operating with the zeros.U The scheme adopted by the... general purpose numerical mathematics subroutines began. The subroutines are written in ANSI standard Fortran. This manual describes the subroutines in...PLCOPYDPCOPY ............ ...................... 113 Addition of Polynomials - PADD ,DPADD ............. .................. I.... 115 Subtraction of

287. Dennis Hill, Photographer July 1998 DETAIL VIEW OF UPPER ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

287. Dennis Hill, Photographer July 1998 DETAIL VIEW OF UPPER CHORD OF THROUGH TRUSS AT PANEL POINT, FACING NORTHWEST. - San Francisco Oakland Bay Bridge, Spanning San Francisco Bay, San Francisco, San Francisco County, CA

45 CFR 287.130 - Can NEW Program activities include job market assessments, job creation and economic development...

Code of Federal Regulations, 2011 CFR

2011-10-01

... Program Design and Operations § 287.130 Can NEW Program activities include job market assessments, job...-sufficiency of program participants; (6) Surveys to collect information regarding client characteristics; and...

45 CFR 287.130 - Can NEW Program activities include job market assessments, job creation and economic development...

Code of Federal Regulations, 2014 CFR

2014-10-01

... Program Design and Operations § 287.130 Can NEW Program activities include job market assessments, job...-sufficiency of program participants; (6) Surveys to collect information regarding client characteristics; and...

17 CFR 287.101 - Schedule A-Information required in reports pursuant to § 287.3.

Code of Federal Regulations, 2010 CFR

2010-04-01

... practicable, the itemization shall include transfer agents' fees, cost of printing and engraving, and legal and accounting fees. The information may be given as subject to future contingencies. If the amounts...

32 CFR 287.5 - Responsibilities

Code of Federal Regulations, 2011 CFR

2011-07-01

... capricious withholding of records requested, pursuant to the Freedom of Information Act, by military members... Counsel, Defense Information Technology Contracting Organization (DITCO). The Chief Legal Counsel, DITCO... INFORMATION ACT PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY FREEDOM OF INFORMATION ACT PROGRAM § 287.5...

32 CFR 287.5 - Responsibilities

Code of Federal Regulations, 2010 CFR

2010-07-01

... capricious withholding of records requested, pursuant to the Freedom of Information Act, by military members... Counsel, Defense Information Technology Contracting Organization (DITCO). The Chief Legal Counsel, DITCO... INFORMATION ACT PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY FREEDOM OF INFORMATION ACT PROGRAM § 287.5...

32 CFR 287.5 - Responsibilities

Code of Federal Regulations, 2014 CFR

2014-07-01

... capricious withholding of records requested, pursuant to the Freedom of Information Act, by military members... Counsel, Defense Information Technology Contracting Organization (DITCO). The Chief Legal Counsel, DITCO... INFORMATION ACT PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY FREEDOM OF INFORMATION ACT PROGRAM § 287.5...

32 CFR 287.5 - Responsibilities

Code of Federal Regulations, 2012 CFR

2012-07-01

... capricious withholding of records requested, pursuant to the Freedom of Information Act, by military members... Counsel, Defense Information Technology Contracting Organization (DITCO). The Chief Legal Counsel, DITCO... INFORMATION ACT PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY FREEDOM OF INFORMATION ACT PROGRAM § 287.5...

32 CFR 287.5 - Responsibilities

Code of Federal Regulations, 2013 CFR

2013-07-01

... capricious withholding of records requested, pursuant to the Freedom of Information Act, by military members... Counsel, Defense Information Technology Contracting Organization (DITCO). The Chief Legal Counsel, DITCO... INFORMATION ACT PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY FREEDOM OF INFORMATION ACT PROGRAM § 287.5...

45 CFR 287.5 - What is the purpose and scope of the NEW Program?

Code of Federal Regulations, 2010 CFR

2010-10-01

... NATIVE EMPLOYMENT WORKS (NEW) PROGRAM General NEW Provisions § 287.5 What is the purpose and scope of the... Native organizations, the opportunity to provide work activities and services to their needy clients. ...

32 CFR 287.6 - Duties of the DITCO and the DTIC FOIA officers.

Code of Federal Regulations, 2010 CFR

2010-07-01

... DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY FREEDOM OF INFORMATION ACT PROGRAM § 287.6 Duties of the DITCO and the DTIC FOIA officers. (a) DITCO FOIA Officer. The...

49 CFR 192.287 - Plastic pipe: Inspection of joints.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Section 192.287 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Joining of Materials Other...

R1 in the Shaker S4 occupies the gating charge transfer center in the resting state

PubMed Central

Lin, Meng-chin A.; Hsieh, Jui-Yi; Mock, Allan F.

2011-01-01

During voltage-dependent activation in Shaker channels, four arginine residues in the S4 segment (R1–R4) cross the transmembrane electric field. It has been proposed that R1–R4 movement is facilitated by a “gating charge transfer center” comprising a phenylalanine (F290) in S2 plus two acidic residues, one each in S2 and S3. According to this proposal, R1 occupies the charge transfer center in the resting state, defined as the conformation in which S4 is maximally retracted toward the cytoplasm. However, other evidence suggests that R1 is located extracellular to the charge transfer center, near I287 in S2, in the resting state. To investigate the resting position of R1, we mutated I287 to histidine (I287H), paired it with histidine mutations of key voltage sensor residues, and determined the effect of extracellular Zn2+ on channel activity. In I287H+R1H, Zn2+ generated a slow component of activation with a maximum amplitude (Aslow,max) of ∼56%, indicating that only a fraction of voltage sensors can bind Zn2+ at a holding potential of −80 mV. Aslow,max decreased after applying either depolarizing or hyperpolarizing prepulses from −80 mV. The decline of Aslow,max after negative prepulses indicates that R1 moves inward to abolish ion binding, going beyond the point where reorientation of the I287H and R1H side chains would reestablish a binding site. These data support the proposal that R1 occupies the charge transfer center upon hyperpolarization. Consistent with this, pairing I287H with A359H in the S3–S4 loop generated a Zn2+-binding site. At saturating concentrations, Aslow,max reached 100%, indicating that Zn2+ traps the I287H+A359H voltage sensor in an absorbing conformation. Transferring I287H+A359H into a mutant background that stabilizes the resting state significantly enhanced Zn2+ binding at −80 mV. Our results strongly support the conclusion that R1 occupies the gating charge transfer center in the resting conformation. PMID:21788609

Electro and Magneto-Electropolished Surface Micro-Patterning on Binary and Ternary Nitinol

PubMed Central

Munroe, Norman; McGoron, Anthony

2012-01-01

In this study, an Atomic Force Microscopy (AFM) roughness analysis was performed on non-commercial Nitinol alloys with Electropolished (EP) and Magneto-Electropolished (MEP) surface treatments and commercially available stents by measuring Root-Mean-Square (RMS), Average Roughness (Ra), and Surface Area (SA) values at various dimensional areas on the alloy surfaces, ranging from (800 × 800 nm) to (115 × 115μm), and (800 × 800 nm) to (40 × 40 μm) on the commercial stents. Results showed that NiTi-Ta 10 wt% with an EP surface treatment yielded the highest overall roughness, while the NiTi-Cu 10 wt% alloy had the lowest roughness when analyzed over (115 × 115 μm). Scanning Electron Microscopy (SEM) and Energy Dispersive Spectroscopy (EDS) analysis revealed unique surface morphologies for surface treated alloys, as well as an aggregation of ternary elements Cr and Cu at grain boundaries in MEP and EP surface treated alloys, and non-surface treated alloys. Such surface micro-patterning on ternary Nitinol alloys could increase cellular adhesion and accelerate surface endothelialization of endovascular stents, thus reducing the likelihood of in-stent restenosis and provide insight into hemodynamic flow regimes and the corrosion behavior of an implantable device influenced from such surface micro-patterns. PMID:22754200

Simple method for self-referenced and lable-free biosensing by using a capillary sensing element.

PubMed

Liu, Yun; Chen, Shimeng; Liu, Qiang; Liu, Zigeng; Wei, Peng

2017-05-15

We demonstrated a simple method for self-reference and label free biosensing based on a capillary sensing element and common optoelectronic devices. The capillary sensing element is illuminated by a light-emitting diode (LED) light source and detected by a webcam. Part of gold film that deposited on the tubing wall is functionalized to carry on the biological information in the excited SPR modes. The end face of the capillary was monitored and separate regions of interest (ROIs) were selected as the measurement channel and the reference channel. In the ROIs, the biological information can be accurately extracted from the image by simple image processing. Moreover, temperature fluctuation, bulk RI fluctuation, light source fluctuation and other factors can be effectively compensated during detection. Our biosensing device has a sensitivity of 1145%/RIU and a resolution better than 5.287 × 10 -4 RIU, considering a 0.79% noise level. We apply it for concanavalin A (Con A) biological measurement, which has an approximately linear response to the specific analyte concentration. This simple method provides a new approach for multichannel SPR sensing and reference-compensated calibration of SPR signal for label-free detection.

Studies on fast triggering and high precision tracking with Resistive Plate Chambers

NASA Astrophysics Data System (ADS)

Aielli, G.; Ball, R.; Bilki, B.; Chapman, J. W.; Cardarelli, R.; Dai, T.; Diehl, E.; Dubbert, J.; Ferretti, C.; Feng, H.; Francis, K.; Guan, L.; Han, L.; Hou, S.; Levin, D.; Li, B.; Liu, L.; Paolozzi, L.; Repond, J.; Roloff, J.; Santonico, R.; Song, H. Y.; Wang, X. L.; Wu, Y.; Xia, L.; Xu, L.; Zhao, T.; Zhao, Z.; Zhou, B.; Zhu, J.

2013-06-01

We report on studies of fast triggering and high precision tracking using Resistive Plate Chambers (RPCs). Two beam tests were carried out with the 180 GeV/c muon beam at CERN using glass RPCs with gas gaps of 1.15 mm and equipped with readout strips with 1.27 mm pitch. This is the first beam test of RPCs with fine-pitch readout strips that explores precision tracking and triggering capabilities. RPC signals were acquired with precision timing and charge integrating readout electronics at both ends of the strips. The time resolution was measured to be better than 600 ps and the average spatial resolution was found to be 220 μm using charge information and 287 μm only using signal arrival time information. The dual-ended readout allows the determination of the average and the difference of the signal arrival times. The average time was found to be independent of the incident particle position along the strip and is useful for triggering purposes. The time difference yielded a determination of the hit position with a precision of 7.5 mm along the strip. These results demonstrate the feasibility using RPCs for fast and high-resolution triggering and tracking.

Intentional and inadvertent non-adherence in adult coeliac disease. A cross-sectional survey.

PubMed

Hall, Nicola J; Rubin, Gregory P; Charnock, Anne

2013-09-01

Adherence to a gluten-free diet is the mainstay of treatment for coeliac disease. Non-adherence is common as the diet is restrictive and can be difficult to follow. This study aimed to determine the rates of intentional and inadvertent non-adherence in adult coeliac disease and to examine the factors associated with both. A self-completion questionnaire was mailed to adult coeliac patients identified from the computer records of 31 family practices within the North East of England. We received 287 responses after one reminder. Intentional gluten consumption was reported by 115 (40%) of respondents. 155 (54%) had made at least one known mistaken lapse over the same period and 82 (29%) reported neither intentional nor mistaken gluten consumption. Using logistic regression analysis, low self-efficacy, perceptions of tolerance to gluten and intention were found to be independently predictive of intentional gluten consumption. A statistical model predicted 71.8% of cases reporting intentional lapses. Intentional non-adherence to the GFD was found to be common but not as frequent as inadvertent lapses. Distinguishing the factors influencing both intentional and inadvertent non-adherence is useful in understanding dietary self-management in coeliac disease. Copyright © 2013 Elsevier Ltd. All rights reserved.

78 FR 20927 - Tobacco Products Scientific Advisory Committee; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-08

...., Rockville, MD 20850, 1-877-287- 1373. Contact Person: Caryn Cohen, Center for Tobacco Products, Food and Drug Administration, 9200 Corporate Blvd., Rockville, MD 20850, 1-877- 287-1373 (choose option 5..., an order from [[Page 20928

32 CFR 287.1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) FREEDOM OF INFORMATION ACT PROGRAM DEFENSE INFORMATION SYSTEMS AGENCY FREEDOM OF INFORMATION ACT PROGRAM § 287.1 Purpose. This part assigns responsibilities for the Freedom of Information Act (FOIA) Program for DISA. ...

75 FR 9589 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-03

... DEPARTMENT OF ENERGY Agency Information Collection Extension AGENCY: U.S. Department of Energy... Building, U. S. Department of Energy, Washington, DC 20585-1615, [email protected] CONTACT: Helene Mattiello, at the above address, or by telephone at (202) 287-1593, or by fax at (202) 287...

New Jersey I-80 and I-287 HOV lane case study

DOT National Transportation Integrated Search

2000-07-01

This report documents the New Jersey I-80 and I-287 high-occupancy vehicle (HOV) lane case study. Information is presented on planning, implementing, operating, and redesignating the HOV lanes on the two freeways. The operation of the lanes is compar...

Technical Communications in Urban Operations (Les communications techniques en operations urbaines)

DTIC Science & Technology

2010-09-01

SCUTI – Scuola Trasmissioni ed Informatica dell’Esercito Italiano Via dei Genieri, 287, 00143-Roma Cecchignola Email: Mario.DiStefano@selex...comms.com Lt. Fabrizio LAMBIASE SCUTI – Scuola Trasmissioni ed Informatica dell’Esercito Italiano Via dei Genieri, 287, 00143 Roma Cecchignola

Protecting the U.S. Perimeter: Border Searches Under the Fourth Amendment

DTIC Science & Technology

2009-06-29

See also 8 C.F.R. § 287.5(c)(4). 24 See Zepeda v. INS, 753 F.2d. 719, 725-26 (9th Cir. 1983) (agreeing with the government’s argument that § 287...questions of anyone as long as the immigration officer does not restrain the freedom of an individual, not under arrest, to walk away.”). 38 Zepeda ...466 U.S. at 216. See also Zepeda , 753 F.2d at 730. 40 8 C.F.R. § 287.8(b)(2). 41 INS v. Lopez-Mendoza, 468 U.S. 1032, 1046 (1984). See also Mapp v

Classification of Particle Numbers with Unique Heitmann-Radin Minimizer

NASA Astrophysics Data System (ADS)

De Luca, Lucia; Friesecke, Gero

2017-06-01

We show that minimizers of the Heitmann-Radin energy (Heitmann and Radin in J Stat Phys 22(3):281-287, 1980) are unique if and only if the particle number N belongs to an infinite sequence whose first thirty-five elements are 1, 2, 3, 4, 5, 7, 8, 10, 12, 14, 16, 19, 21, 24, 27, 30, 33, 37, 40, 44, 48, 52, 56, 61, 65, 70, 75, 80, 85, 91, 96, 102, 108, 114, 120 (see the paper for a closed-form description of this sequence). The proof relies on the discrete differential geometry techniques introduced in De Luca and Friesecke (Crystallization in two dimensions and a discrete Gauss-Bonnet Theorem, 2016).

8 CFR 287.1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... the baselines of the United States determined in accordance with international law. (2) Reasonable distance. The term reasonable distance, as used in section 287(a) (3) of the Act, means within 100 air... air miles pursuant to paragraph (a) of this section, chief patrol agents and special agents in charge...

8 CFR 287.1 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... the baselines of the United States determined in accordance with international law. (2) Reasonable distance. The term reasonable distance, as used in section 287(a) (3) of the Act, means within 100 air... air miles pursuant to paragraph (a) of this section, chief patrol agents and special agents in charge...

8 CFR 287.1 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... the baselines of the United States determined in accordance with international law. (2) Reasonable distance. The term reasonable distance, as used in section 287(a) (3) of the Act, means within 100 air... air miles pursuant to paragraph (a) of this section, chief patrol agents and special agents in charge...

8 CFR 287.1 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... the baselines of the United States determined in accordance with international law. (2) Reasonable distance. The term reasonable distance, as used in section 287(a) (3) of the Act, means within 100 air... air miles pursuant to paragraph (a) of this section, chief patrol agents and special agents in charge...

8 CFR 287.1 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... the baselines of the United States determined in accordance with international law. (2) Reasonable distance. The term reasonable distance, as used in section 287(a) (3) of the Act, means within 100 air... air miles pursuant to paragraph (a) of this section, chief patrol agents and special agents in charge...

76 FR 79665 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-22

... DEPARTMENT OF ENERGY Agency Information Collection Extension AGENCY: U.S. Department of Energy... to Robert M. Myers, U.S. Department of Energy, 1000 Independence Avenue SW., Washington, DC 20585-1615, 202-287-1584, or by fax at (202) 287- 1349, or by email at [email protected] . FOR FURTHER...

75 FR 34974 - Notice of Proposed Change to Section IV of the Virginia State Technical Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-21

... DEPARTMENT OF AGRICULTURE Natural Resources Conservation Service Notice of Proposed Change to Section IV of the Virginia State Technical Guide AGENCY: Natural Resources Conservation Service (NRCS), U... Road, Suite 209, Richmond, Virginia 23229-5014; Telephone number (804) 287-1691; Fax number (804) 287...

78 FR 706 - Revised Non-Foreign Overseas Per Diem Rates

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-04

... Civilian Personnel Per Diem Bulletin Number 287. This bulletin lists revisions in the per diem rates prescribed for U.S. Government employees for official travel in Alaska, Hawaii, Puerto Rico, the Northern... in effect. Bulletin Number 287 is being published in the Federal Register to assure that travelers...

75 FR 9403 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-02

... DEPARTMENT OF ENERGY Agency Information Collection Extension AGENCY: U.S. Department of Energy... Specialist, MA-632/ L'Enfant Plaza Building, U.S. Department of Energy, Washington, DC 20585-1615, helene... telephone at (202) 287-1593, or by fax at (202) 287- 1656. The Exchange/Sale report form can be found at the...

45 CFR 287.1 - What does this part cover?

Code of Federal Regulations, 2010 CFR

2010-10-01

... specifies.” (c) We call this Tribal work activities program the Native Employment Works (NEW) program. (d...), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM General NEW Provisions § 287.1 What does this part cover? (a) The regulations in this...

46 CFR 287.24 - Extent of tax liability.

Code of Federal Regulations, 2013 CFR

2013-10-01

... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.24 Extent of tax liability. (a) Declared value... case of deposits in the construction reserve fund of amounts derived from sources other than those... regard to the provisions of section 511(c) of the Act. (c) Time for filing claim subsequent to election...

46 CFR 287.24 - Extent of tax liability.

Code of Federal Regulations, 2014 CFR

2014-10-01

... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.24 Extent of tax liability. (a) Declared value... case of deposits in the construction reserve fund of amounts derived from sources other than those... regard to the provisions of section 511(c) of the Act. (c) Time for filing claim subsequent to election...

46 CFR 287.24 - Extent of tax liability.

Code of Federal Regulations, 2012 CFR

2012-10-01

... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.24 Extent of tax liability. (a) Declared value... case of deposits in the construction reserve fund of amounts derived from sources other than those... regard to the provisions of section 511(c) of the Act. (c) Time for filing claim subsequent to election...

46 CFR 287.24 - Extent of tax liability.

Code of Federal Regulations, 2011 CFR

2011-10-01

... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.24 Extent of tax liability. (a) Declared value... case of deposits in the construction reserve fund of amounts derived from sources other than those... regard to the provisions of section 511(c) of the Act. (c) Time for filing claim subsequent to election...

Decay spectroscopy of element 115 daughters: Rg 280 → Mt 276 and Mt 276 → Bh 272

DOE PAGES

Gates, J. M.; Gregorich, K. E.; Gothe, O. R.; ...

2015-08-03

In this study, forty-six decay chains, assigned to the decay of 288115, were produced using the 243Am ( 48Ca, 3n) 288115 reaction at the Lawrence Berkeley National Laboratory 88-in. cyclotron. The resulting series of α decays were studied using α-photon and α-x-ray spectroscopies. Multiple α-photon coincidences were observed in the element 115 decay chain members, particularly in the third- and fourth-generation decays (presumed to be 280Rg and 276Mt, respectively). Upon combining these data with those from 22 288115 decay chains observed in a similar experiment, updated level schemes in 276Mt and 272Bh (populated by the α decay of 280Rg andmore » 276Mt, respectively) are proposed. Additionally, photons were observed in the energy range expected for K x rays coincident with the α decay of both 280Rg and 276Mt. However, Compton scattering of higher-energy γ rays and discrete transitions are present in the K x-ray region preventing a definitive Z identification to be made based on observation of characteristic K x-ray energies.« less

STS115-S-001

NASA Image and Video Library

2003-02-01

STS115-S-001 (February 2003) --- This is the STS-115 insignia. This mission continues the assembly of the International Space Station (ISS) with the installation of the truss segments P3 and P4. Following the installation of the segments utilizing both the shuttle and the station robotic arms, a series of three spacewalks will complete the final connections and prepare for the deployment of the station's second set of solar arrays. To reflect the primary mission of the flight, the patch depicts a solar panel as the main element. As the space shuttle Atlantis launches towards the ISS, its trail depicts the symbol of the Astronaut Office. The starburst, representing the power of the sun, rises over the Earth and shines on the solar panel. The shuttle flight number 115 is shown at the bottom of the patch, along with the ISS assembly designation 12A (the 12th American assembly mission). The blue Earth in the background reminds us of the importance of space exploration and research to all of Earth's inhabitants. The NASA insignia design for space shuttle flights is reserved for use by the astronauts and for other official use as the NASA Administrator may authorize. Public availability has been approved only in the forms of illustrations by the various news media. When and if there is any change in this policy, which is not anticipated, the change will be publicly announced. Photo credit: NASA

Extraordinary Activity in the BL Lacertae Object OJ 287

NASA Astrophysics Data System (ADS)

Hughes, Philip A.; Aller, Hugh D.; Aller, Margo F.

1998-08-01

We use a continuous wavelet transform to analyze more than two decades of data for the BL Lac object OJ 287 acquired as part of the University of Michigan Radio Astronomy Observatory (UMRAO) variability program. We find clear evidence for a persistent modulation of the total flux and polarization with period ~1.66 yr and for another signal that dominates activity in the 1980s with period ~1.12 yr. The relationship between these two variations can be understood in terms of a ``shock-in-jet'' model, in which the longer timescale periodicity is associated with an otherwise quiescent jet and the shorter timescale activity is associated with the passage of a shock. The different periodicities of these two components may reflect different internal conditions of the two flow domains leading to different wave speeds or different contractions of a single underlying periodicity due to the different Doppler factors of the two flow components. We suggest that the modulation arises from a wave driven by some asymmetric disturbance close to the central engine. The periodic behavior in polarization exhibits excursions in U that correspond to a direction ~45° from the VLBI jet axis. This behavior is not explained by the random walk in the Q-U plane that is expected from models in which a pattern of randomly aligned magnetic field elements propagate across the visible portion of the flow and suggests a small amplitude, cyclic variation in the flow direction in that part of the flow that dominates centimeter wavelength emission.

8 CFR 287.5 - Exercise of power by immigration officers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Exercise of power by immigration officers... FIELD OFFICERS; POWERS AND DUTIES § 287.5 Exercise of power by immigration officers. (a) Power and... hereby authorized and designated to exercise anywhere in or outside the United States the power conferred...

8 CFR 287.7 - Detainer provisions under section 287(d)(3) of the Act.

Code of Federal Regulations, 2010 CFR

2010-01-01

... advise another law enforcement agency that the Department seeks custody of an alien presently in the... detainers: (1) Border patrol agents, including aircraft pilots; (2) Special agents; (3) Deportation officers... with this section, the criminal justice agency requesting such action or informing the Department of a...

45 CFR 287.90 - Are Tribes required to complete any certifications?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 2 2012-10-01 2012-10-01 false Are Tribes required to complete any certifications... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Plan Requirements § 287.90 Are Tribes required to complete any certifications? Yes. A Tribe must include in its NEW Program plan the following four...

45 CFR 287.90 - Are Tribes required to complete any certifications?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true Are Tribes required to complete any certifications... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Plan Requirements § 287.90 Are Tribes required to complete any certifications? Yes. A Tribe must include in its NEW Program plan the following four...

45 CFR 287.90 - Are Tribes required to complete any certifications?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 2 2014-10-01 2012-10-01 true Are Tribes required to complete any certifications... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Plan Requirements § 287.90 Are Tribes required to complete any certifications? Yes. A Tribe must include in its NEW Program plan the following four...

45 CFR 287.90 - Are Tribes required to complete any certifications?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false Are Tribes required to complete any certifications... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Plan Requirements § 287.90 Are Tribes required to complete any certifications? Yes. A Tribe must include in its NEW Program plan the following four...

75 FR 47259 - Notice of Proposed Change to Section IV of the Virginia State Technical Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-05

... DEPARTMENT OF AGRICULTURE Natural Resources Conservation Service Notice of Proposed Change to Section IV of the Virginia State Technical Guide AGENCY: Natural Resources Conservation Service (NRCS), U..., Virginia 23229-5014; Telephone number (804) 287-1691; Fax number (804) 287-1737. Copies of the practice...

75 FR 50955 - Proposed Flood Elevation Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-18

... the intersection of of Kennebunk, Town of Great Hill Road and Kennebunkport, Town of Sand Dollar Lane... Boston Road. Little Ossipee River Approximately 0.6 mile None +287 Town of Hollis. upstream of Sand Pond Road. Approximately 0.9 mile None +287 upstream of Sand Pond Road. Little River Just upstream of the...

45 CFR 287.130 - Can NEW Program activities include job market assessments, job creation and economic development...

Code of Federal Regulations, 2012 CFR

2012-10-01

... Program Design and Operations § 287.130 Can NEW Program activities include job market assessments, job...) Communication with any training, research, or educational agencies that have produced economic development plans...-sufficiency of program participants; (6) Surveys to collect information regarding client characteristics; and...

45 CFR 287.130 - Can NEW Program activities include job market assessments, job creation and economic development...

Code of Federal Regulations, 2013 CFR

2013-10-01

... Program Design and Operations § 287.130 Can NEW Program activities include job market assessments, job...) Communication with any training, research, or educational agencies that have produced economic development plans...-sufficiency of program participants; (6) Surveys to collect information regarding client characteristics; and...

45 CFR 287.130 - Can NEW Program activities include job market assessments, job creation and economic development...

Code of Federal Regulations, 2010 CFR

2010-10-01

... Program Design and Operations § 287.130 Can NEW Program activities include job market assessments, job...) Communication with any training, research, or educational agencies that have produced economic development plans...-sufficiency of program participants; (6) Surveys to collect information regarding client characteristics; and...

46 CFR 287.4 - Application to establish fund.

Code of Federal Regulations, 2014 CFR

2014-10-01

... vessel built to specifications, or (b) to acquire a vessel already constructed or under construction. If... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.4 Application to establish fund. (a) Any person claiming to be entitled to the benefits of section 511 of the Act may make application, in writing, to the...

46 CFR 287.4 - Application to establish fund.

Code of Federal Regulations, 2012 CFR

2012-10-01

... vessel built to specifications, or (b) to acquire a vessel already constructed or under construction. If... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.4 Application to establish fund. (a) Any person claiming to be entitled to the benefits of section 511 of the Act may make application, in writing, to the...

46 CFR 287.4 - Application to establish fund.

Code of Federal Regulations, 2011 CFR

2011-10-01

... vessel built to specifications, or (b) to acquire a vessel already constructed or under construction. If... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.4 Application to establish fund. (a) Any person claiming to be entitled to the benefits of section 511 of the Act may make application, in writing, to the...

46 CFR 287.4 - Application to establish fund.

Code of Federal Regulations, 2010 CFR

2010-10-01

... vessel built to specifications, or (b) to acquire a vessel already constructed or under construction. If... OPERATORS ESTABLISHMENT OF CONSTRUCTION RESERVE FUNDS § 287.4 Application to establish fund. (a) Any person claiming to be entitled to the benefits of section 511 of the Act may make application, in writing, to the...

Characterization of Two Mutations, M287L and Q266I, in the α1 Glycine Receptor Subunit That Modify Sensitivity to Alcohols

PubMed Central

Borghese, Cecilia M.; Blednov, Yuri A.; Quan, Yu; Iyer, Sangeetha V.; Xiong, Wei; Mihic, S. John; Zhang, Li; Lovinger, David M.; Trudell, James R.; Homanics, Gregg E.

2012-01-01

Glycine receptors (GlyRs) are inhibitory ligand-gated ion channels. Ethanol potentiates glycine activation of the GlyR, and putative binding sites for alcohol are located in the transmembrane (TM) domains between and within subunits. To alter alcohol sensitivity of GlyR, we introduced two mutations in the GlyR α1 subunit, M287L (TM3) and Q266I (TM2). After expression in Xenopus laevis oocytes, both mutants showed a reduction in glycine sensitivity and glycine-induced maximal currents. Activation by taurine, another endogenous agonist, was almost abolished in the M287L GlyR. The ethanol potentiation of glycine currents was reduced in the M287L GlyR and eliminated in Q266I. Physiological levels of zinc (100 nM) potentiate glycine responses in wild-type GlyR and also enhance the ethanol potentiation of glycine responses. Although zinc potentiation of glycine responses was unchanged in both mutants, zinc enhancement of ethanol potentiation of glycine responses was absent in M287L GlyRs. The Q266I mutation decreased conductance but increased mean open time (effects not seen in M287L). Two lines of knockin mice bearing these mutations were developed. Survival of homozygous knockin mice was impaired, probably as a consequence of impaired glycinergic transmission. Glycine showed a decreased capacity for displacing strychnine binding in heterozygous knockin mice. Electrophysiology in isolated neurons of brain stem showed decreased glycine-mediated currents and decreased ethanol potentiation in homozygous knockin mice. Molecular models of the wild-type and mutant GlyRs show a smaller water-filled cavity within the TM domains of the Q266I α1 subunit. The behavioral characterization of these knockin mice is presented in a companion article (J Pharmacol Exp Ther 340:317–329, 2012). PMID:22037201

[Long-term outcome of surgical revascularization in patients with ischemic heart disease and left ventricular dysfunction].

PubMed

Wang, R; Gao, C Q; Xiao, C S; Wu, Y; Ren, C L; Gong, Z Y; Wang, Y; Liu, G P; Wang, M Y

2016-04-19

To analyze the long-term results and risk factors of surgical revascularization in patients with ischemic heart disease (IHD) and left ventricular dysfunction (LVD). From January 2003 to July 2013, 2 132 patients underwent coronary artery bypass grafting (CABG) in our institution. Among them, 318 patients with LVD[left ventricular ejection fraction (LVEF) ≤50%]were included in the final study. There were 26 6 male and 52 female patients with age from 36 to 83 (63±9) years old. 76 patients underwent off-pump CABG (OPCAB) and 242 patients underwent conventional CABG (CCABG). Risk factors, perioperative results and follow-up data were collected and analyzed with cox hazard ratio model. Among 318 patients, 6 cases died of the operation with a hospital mortality of 1.9%. With follow-up time from 1 to 128(45.5±32.4)months, 25 patients were lost of follow-up, causing a follow-up rate of 92.0%. Among the 287 cases with long-term follow-up results, all-cause death, cardiogenic death and re-hospitalization due to heart failure were 14.6% (42/287), 5.9%(17/287), 14.6% (42/287), respectively. Re-revascularization rate, recurrent angina and myocardial infarction rate and cerebral incidence were 3.5%(10/287), 13.6% (39/287), 1.7%(5/287), respectively. The five-year survival rate was 85.6%. With all-cause death as the endpoint, preoperative LVEF (HR=0.943, 95%CI: 0.893-0.995, P=0.031) and perioperative implantation of IABP (HR=2.509, 95%CI: 1.051-5.992, P=0.038) emerged as the risk factors that affected the long term survival. The five-year survival rate of patients with severe LVD (LVEF≤35%) was significantly lower than that of patients with mild to moderate LVD (35%

Specific Needs for Updating Educational Experiences as Reported by Instructors of Electronics in Industrial Education Departments of Colleges and Universities.

ERIC Educational Resources Information Center

Slater, John Breisch

A survey of 133 industrial education electronics instructors in 115 4-year colleges and universities in 40 states was conducted to determine the expressed needs of college level electronics instructors for updating educational experiences in specified elements. An attempt was also made to determine the nature of course content needed in graduate…

Study of rolling element dynamic interactions with separators and raceway paths: Roller to separator contact forces and cage to shaft speed ratios in roller bearings

NASA Technical Reports Server (NTRS)

Nypan, L. J.

1978-01-01

Cage to roller force measurements, cage to shaft forces, and cage to shaft speed ratios are reported for 115 and 118mm bore roller bearings operating at speeds of 4,000, 8,000, and 12,000 rpm under loads ranging from 360 to 6670 N (80 to 1500 lb).

The Motion of Magnetic Elements in and around Sunspot Penumbrae

NASA Astrophysics Data System (ADS)

Grigor'ev, V. M.; Ermakova, L. V.

2018-01-01

Structural magnetic elements observed in sunspot penumbrae are employed as indicators of motions occurring in and around penumbrae. The analysis presented here is base on SDO/HMI continuum images and magnetograms of the line-of-sight field obtained for the active region NOAA 11117. In a first approximation, the penumbral magnetic fields can be considered alternating spines and interspine filaments. In the plane of the sky, spines are thin radial elements with higher field strengths and lower magnetic-field inclinations compared with those in surrounding areas. It is confirmed that spines first appear as protrusions of the umbra magnetic fields visible in magnetograms, and then develop simultaneously with the growth of the penumbra. The departure of magnetic elements from penumbrae as a result of the detachment of the ends of spines begin 1-1.5 h after the spine formation. Inmature penumbrae, magnetic elements emerge fairly often, and the departure of groups of field elements sometimes generates structures resembling moving ribbons. The velocities of magnetic elements that have separated from spines are a factor of two to three lower than those of elements that have separated from inter-spine filaments. The results obtained agree well with an "uncombed" model for the penumbral magnetic fields.

30 CFR 250.287 - For what development projects must I submit a DWOP?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false For what development projects must I submit a... Operations Plans (dwop) § 250.287 For what development projects must I submit a DWOP? You must submit a DWOP for each development project in which you will use non-conventional production or completion...

45 CFR 287.55 - What time frames and guidelines apply regarding the obligation and liquidation periods for NEW...

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false What time frames and guidelines apply regarding... NEW Program Funding § 287.55 What time frames and guidelines apply regarding the obligation and... be returned to the Federal government through the issuance of a negative grant award. Unobligated...

30 CFR 250.287 - For what development projects must I submit a DWOP?

Code of Federal Regulations, 2014 CFR

2014-07-01

... and Information Deepwater Operations Plan (dwop) § 250.287 For what development projects must I submit a DWOP? You must submit a DWOP for each development project in which you will use non-conventional... 30 Mineral Resources 2 2014-07-01 2014-07-01 false For what development projects must I submit a...

30 CFR 250.287 - For what development projects must I submit a DWOP?

Code of Federal Regulations, 2013 CFR

2013-07-01

... and Information Deepwater Operations Plan (dwop) § 250.287 For what development projects must I submit a DWOP? You must submit a DWOP for each development project in which you will use non-conventional... 30 Mineral Resources 2 2013-07-01 2013-07-01 false For what development projects must I submit a...

30 CFR 250.287 - For what development projects must I submit a DWOP?

Code of Federal Regulations, 2012 CFR

2012-07-01

... and Information Deepwater Operations Plan (dwop) § 250.287 For what development projects must I submit a DWOP? You must submit a DWOP for each development project in which you will use non-conventional... 30 Mineral Resources 2 2012-07-01 2012-07-01 false For what development projects must I submit a...

30 CFR 250.287 - For what development projects must I submit a DWOP?

Code of Federal Regulations, 2011 CFR

2011-07-01

... SHELF Plans and Information Deepwater Operations Plans (dwop) § 250.287 For what development projects must I submit a DWOP? You must submit a DWOP for each development project in which you will use non... 30 Mineral Resources 2 2011-07-01 2011-07-01 false For what development projects must I submit a...

75 FR 33761 - Notice of Proposed Change to Section IV of the Virginia State Technical Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-15

... Section IV of the Virginia State Technical Guide AGENCY: Natural Resources Conservation Service (NRCS), U... Rosa Road, Suite 209, Richmond, Virginia 23229-5014; Telephone number (804) 287-1691; Fax number (804) 287-1737. Copies of the practice standards will be made available upon written request to the address...

76 FR 2145 - Masco Builder Cabinet Group Including On-Site Leased Workers From Reserves Network, Jackson, OH...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-12

...,287B; TA-W-71,287C] Masco Builder Cabinet Group Including On-Site Leased Workers From Reserves Network, Jackson, OH; Masco Builder Cabinet Group, Waverly, OH; Masco Builder Cabinet Group, Seal Township, OH; Masco Builder Cabinet Group, Seaman, OH; Amended Certification Regarding Eligibility To Apply for Worker...

40 CFR 96.287 - Change in regulatory status.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS CAIR SO2 Opt-in Units § 96.287 Change in regulatory status. (a) Notification. If a CAIR SO2 opt-in unit becomes a CAIR SO2 unit under § 96.204, then the CAIR designated representative shall notify in writing...

Predicting Chromophoric Dissolved Organic Matter Distributions in Coastal Waters

DTIC Science & Technology

2006-01-01

Predicting Chromophoric Dissolved Organic Matter Distributions in Coastal Waters Robert F. Chen Environmental , Earth and Ocean Sciences...G. Bernard Gardner Environmental , Coastal and Ocean Sciences University of Massachusetts Boston 100 Morrissey Boulevard Boston, MA 02125-3393...phone: (617)287-7451 fax: (617)287-7474 email: bernie.gardner@umb.edu Yong Tian Environmental , Coastal and Ocean Sciences University of

Predicting Chromophoric Dissolved Organic Matter Distributions in Coastal Waters

DTIC Science & Technology

2007-09-30

Predicting Chromophoric Dissolved Organic Matter Distributions in Coastal Waters Robert F. Chen Environmental , Earth and Ocean Sciences...G. Bernard Gardner Environmental , Coastal and Ocean Sciences University of Massachusetts Boston 100 Morrissey Boulevard Boston, MA 02125-3393...phone: (617)287-7451 fax: (617)287-7474 email: bernie.gardner@umb.edu Yong Tian Environmental , Coastal and Ocean Sciences University of

Predicting Chromophoric Dissolved Organic Matter Distributions in Coastal Waters

DTIC Science & Technology

2008-09-30

Predicting Chromophoric Dissolved Organic Matter Distributions in Coastal Waters Robert F. Chen Environmental , Earth and Ocean...umb.edu G. Bernard Gardner Environmental , Coastal and Ocean Sciences University of Massachusetts Boston 100 Morrissey Boulevard Boston, MA...02125-3393 phone: (617) 287-7451 fax: (617) 287-7474 email: bernie.gardner@umb.edu Yong Tian Environmental , Coastal and Ocean Sciences

8 CFR 287.8 - Standards for enforcement activities.

Code of Federal Regulations, 2013 CFR

2013-01-01

... or such other entity as may be provided for in 8 CFR 287.10. (a) Use of force—(1) Non-deadly force. (i) Non-deadly force is any use of force other than that which is considered deadly force as defined in paragraph (a)(2) of this section. (ii) Non-deadly force may be used only when a designated...

8 CFR 287.8 - Standards for enforcement activities.

Code of Federal Regulations, 2014 CFR

2014-01-01

... or such other entity as may be provided for in 8 CFR 287.10. (a) Use of force—(1) Non-deadly force. (i) Non-deadly force is any use of force other than that which is considered deadly force as defined in paragraph (a)(2) of this section. (ii) Non-deadly force may be used only when a designated...

8 CFR 287.8 - Standards for enforcement activities.

Code of Federal Regulations, 2012 CFR

2012-01-01

... or such other entity as may be provided for in 8 CFR 287.10. (a) Use of force—(1) Non-deadly force. (i) Non-deadly force is any use of force other than that which is considered deadly force as defined in paragraph (a)(2) of this section. (ii) Non-deadly force may be used only when a designated...

8 CFR 287.8 - Standards for enforcement activities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... or such other entity as may be provided for in 8 CFR 287.10. (a) Use of force—(1) Non-deadly force. (i) Non-deadly force is any use of force other than that which is considered deadly force as defined in paragraph (a)(2) of this section. (ii) Non-deadly force may be used only when a designated...

45 CFR 287.70 - What are the plan requirements for the NEW Program?

Code of Federal Regulations, 2010 CFR

2010-10-01

... Tribe will deliver work activities and services. (d) The format is left to the discretion of each NEW... 45 Public Welfare 2 2010-10-01 2010-10-01 false What are the plan requirements for the NEW Program... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Plan Requirements § 287.70 What are the plan...

45 CFR 287.70 - What are the plan requirements for the NEW Program?

Code of Federal Regulations, 2011 CFR

2011-10-01

... Tribe will deliver work activities and services. (d) The format is left to the discretion of each NEW... 45 Public Welfare 2 2011-10-01 2011-10-01 false What are the plan requirements for the NEW Program... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Plan Requirements § 287.70 What are the plan...

How elements up to 118 were reached and how to go beyond

NASA Astrophysics Data System (ADS)

Düllmann, Christoph E.

2017-11-01

The new superheavy elements with Z=113, 115, 117, and 118 were recently accepted into the periodic table and have been named. Elements with Z≥112 are predominantly produced in 48Ca-induced fusion reactions on actinide targets. This pathway is exhausted at Z=118 due to the lack of target materials with sufficiently high proton number to reach elements with Z≥119. Search experiments for yet heavier elements were performed at GSI Darmstadt and FLNR Dubna. The reactions 50Ti + 249Bk, which leads to Z=119, as well as 64Ni + 238U, 58Fe + 244Pu, 54Cr + 248Cm, and 50Ti + 249Cf, leading to Z=120, have been studied. Despite a total duration of these experiments of more than one year, neither succeeded in the identification of a new element. To obtain improved guidance for better-informed search experiments, nuclear reaction studies appear necessary and have recently started. Also technical advances will be an important pillar to this end. At GSI, work towards a new continuous-wave linear accelerator is ongoing and is briefly described.

Monitoring Metal Pollution Levels in Mine Wastes around a Coal Mine Site Using GIS

NASA Astrophysics Data System (ADS)

Sanliyuksel Yucel, D.; Yucel, M. A.; Ileri, B.

2017-11-01

In this case study, metal pollution levels in mine wastes at a coal mine site in Etili coal mine (Can coal basin, NW Turkey) are evaluated using geographical information system (GIS) tools. Etili coal mine was operated since the 1980s as an open pit. Acid mine drainage is the main environmental problem around the coal mine. The main environmental contamination source is mine wastes stored around the mine site. Mine wastes were dumped over an extensive area along the riverbeds, and are now abandoned. Mine waste samples were homogenously taken at 10 locations within the sampling area of 102.33 ha. The paste pH and electrical conductivity values of mine wastes ranged from 2.87 to 4.17 and 432 to 2430 μS/cm, respectively. Maximum Al, Fe, Mn, Pb, Zn and Ni concentrations of wastes were measured as 109300, 70600, 309.86, 115.2, 38 and 5.3 mg/kg, respectively. The Al, Fe and Pb concentrations of mine wastes are higher than world surface rock average values. The geochemical analysis results from the study area were presented in the form of maps. The GIS based environmental database will serve as a reference study for our future work.

Incidence and variance of foot and ankle injuries in elite college football players.

PubMed

Kaplan, Lee D; Jost, Patrick W; Honkamp, Nicholas; Norwig, John; West, Robin; Bradley, James P

2011-01-01

We conducted a study on the risk for foot and ankle injuries in college football players on the basis of injury type and player position. In February 2006, we evaluated 320 intercollegiate football players at the National Football League Combine. All pathologic conditions and surgical procedures of the foot and ankle were recorded, and data were analyzed by player position to detect any trends. Seventy-two percent (n = 231) of the players had a history of foot and ankle injuries, with a total of 287 foot and ankle injuries (1.24 injuries/player injured). The most common injuries were lateral ankle sprain (n = 115), syndesmotic sprain (50), metatarsophalangeal dislocation/turf toe (36), and fibular fracture (25). Foot and ankle injuries were most common in kickers/punters (100% incidence), special teams (100%), running backs (83%), wide receivers (83%), and offensive linemen (80%). Lateral ankle sprains, the most common injuries, were treated surgically only 2.6% of the time. Offensive linemen were most likely to have had syndesmotic sprains (32%), and quarterbacks had the highest incidence of fibular fractures (16%). Foot and ankle injuries are common in collegiate football players, affecting 72% of players. Thirteen percent underwent surgical treatment. Trends are seen in the types of injuries for the different player positions.

The relationship between resolution of asymptomatic bacterial vaginosis and spontaneous preterm birth in fetal fibronectin-positive women.

PubMed

Hendler, Israel; Andrews, William W; Carey, Christopher J; Klebanoff, Mark A; Noble, William D; Sibai, Baha M; Hillier, Sharon L; Dudley, Donald; Ernest, Joseph M; Leveno, Kenneth J; Wapner, Ronald; Iams, Jay D; Varner, Michael; Moawad, Atef; Miodovnik, Menachem; O'Sullivan, Mary J; Van Dorsten, Peter J

2007-11-01

The purpose of this study was to determine the impact of persistent bacterial vaginosis (BV) on the occurrence of spontaneous preterm birth (SPB) in women who test positive for fetal fibronectin. This is a secondary analysis of a subset of pregnant women who tested positive for BV and fetal fibronectin between 16(0/7) and 25(6/7) weeks of gestation and who participated in randomized placebo controlled trials of antibiotic therapy. Nugent's criteria were used for the diagnosis of BV. Patients were reassessed for the presence of BV after treatment. The rate of SPB at <34 weeks of gestation was analyzed on the basis of treatment mode and BV status at the follow-up visit. The primary studies included a total of 3285 women. A subset of 215 women met the criteria for this analysis. Seventy-seven of 100 patients (77%) in the antibiotics group vs 33 of the 115 patients (28.7%) in the placebo group became BV negative (P < .0001). The rate of SPB at <34 weeks of gestation was lower for BV resolution compared with persistent BV (0 vs 5.7%, respectively; P = .01). In women who tested positive for fetal fibronectin and BV, resolution of BV is associated with less SPB before 34 weeks of gestation.

Magnetic properties and tunable magneto-caloric effect in La0.8Ce0.2Fe11.5-xCoxSi1.5C0.2 (x = 0.3, 0.5, and 0.7) compounds

NASA Astrophysics Data System (ADS)

Wu, Qiming; Wang, Xiangjie; Ding, Zan; Li, Lingwei

2018-05-01

The magnetic and magneto-caloric properties in the ternary elementals doped La0.8Ce0.2Fe11.5-xCoxSi1.5C0.2 (x = 0.3, 0.5, and 0.7) compounds were studied. With the increases of Co content x, the Curie temperature TC increases and the thermal hysteresis decreases. All the compounds undergo a second-order magnetic phase transition and exhibit a considerable reversible tunable magneto-caloric effect. The values of maximum magnetic entropy change (-ΔSMmax) and the Relative Cooling Power (RCP) are kept at same high level with different Co content. Under a magnetic field change of 0-5 T, the values of -ΔSMmax for La0.8Ce0.2Fe11.5-xCoxSi1.5C0.2 are 10.5, 10.7, and 9.8 J/kg K for x = 0.3, 0.5, and 0.7, respectively. The corresponding values of RCP are 267.1, 289.9, and 290.2 J/kg.

Performance and characterization of new micromachined high-frequency linear arrays.

PubMed

Lukacs, Marc; Yin, Jianhua; Pang, Guofeng; Garcia, Richard C; Cherin, Emmanuel; Williams, Ross; Mehi, Jim; Foster, F Stuart

2006-10-01

A new approach for fabricating high frequency (> 20 MHz) linear array transducers, based on laser micromachining, has been developed. A 30 MHz, 64-element, 74-microm pitch, linear array design is presented. The performance of the device is demonstrated by comparing electrical and acoustic measurements with analytical, equivalent circuit, and finite-element analysis (FEA) simulations. All FEA results for array performance have been generated using one global set of material parameters. Each fabricated array has been integrated onto a flex circuit for ease of handling, and the flex has been integrated onto a custom printed circuit board test card for ease of testing. For a fully assembled array, with an acoustic lens, the center frequency was 28.7 MHz with a one-way -3 dB and -6 dB bandwidth of 59% and 83%, respectively, and a -20 dB pulse width of -99 ns. The per-element peak acoustic power, for a +/- 30 V single cycle pulse, measured at the 10 mm focal length of the lens was 590 kPa with a -6 dB directivity span of about 30 degrees. The worst-case total cross talk of the combined array and flex assembly is for nearest neighboring elements and was measured to have an average level -40 dB across the -6 dB bandwidth of the device. Any significant deviation from simulation can be explained through limitations in apparatus calibration and in device packaging.

75 FR 22095 - Notice of Funds Availability for the Section 533 Housing Preservation Grants for Fiscal Year 2010

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-27

... 23229 (804) 287-1596 TDD (804) 287-1753 CJ Michels Washington State Office 1835 Black Lake Boulevard... (202) 690-0759 (voice) (this is not a toll free number) or (800) 877-8339 (TDD-Federal Information... USDA's TARGET Center at (202) 720-2600 (voice and TDD). To file a complaint of discrimination, write to...

45 CFR 287.15 - Which Tribes are eligible to apply for NEW Program grants?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 2 2012-10-01 2012-10-01 false Which Tribes are eligible to apply for NEW Program... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Eligible Tribes § 287.15 Which Tribes are eligible to apply for NEW Program grants? To be considered for a NEW Program grant, a Tribe must be an “eligible...

45 CFR 287.15 - Which Tribes are eligible to apply for NEW Program grants?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 2 2014-10-01 2012-10-01 true Which Tribes are eligible to apply for NEW Program... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Eligible Tribes § 287.15 Which Tribes are eligible to apply for NEW Program grants? To be considered for a NEW Program grant, a Tribe must be an “eligible...

45 CFR 287.15 - Which Tribes are eligible to apply for NEW Program grants?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true Which Tribes are eligible to apply for NEW Program... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Eligible Tribes § 287.15 Which Tribes are eligible to apply for NEW Program grants? To be considered for a NEW Program grant, a Tribe must be an “eligible...

40 CFR 97.287 - Change in regulatory status.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS CAIR SO2 Opt-in Units § 97.287 Change in regulatory status. (a) Notification. If a CAIR SO2 opt-in unit becomes a CAIR SO2... authority and the Administrator of such change in the CAIR SO2 opt-in unit's regulatory status, within 30...

45 CFR 287.20 - May a Public Law 102-477 Tribe operate a NEW Program?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false May a Public Law 102-477 Tribe operate a NEW... ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Eligible Tribes § 287.20 May a Public Law 102-477 Tribe...

Novel pathways revealed in P. fluorescens Q2-87 and Q8r1-96

USDA-ARS?s Scientific Manuscript database

Pseudomonas fluorescens Q2-87 and Q8r1-96, both from a take-all decline field in Quincy, Washington, U.S.A., are almost indistinguishable in vitro, but only strain Q8r1-96 exhibits the “premier” phenotype distinguished by highly aggressive wheat root colonizing ability essential for the natural dise...

Behavioral Characterization of Knockin Mice with Mutations M287L and Q266I in the Glycine Receptor α1 Subunit

PubMed Central

Blednov, Yuri A.; Benavidez, Jill M.; Homanics, Gregg E.

2012-01-01

We used behavioral pharmacology to characterize heterozygous knockin mice with mutations (Q266I or M287L) in the α1 subunit of the glycine receptor (GlyR) (J Pharmacol Exp Ther 340:304–316, 2012). These mutations were designed to reduce (M287L) or eliminate (Q266I) ethanol potentiation of GlyR function. We asked which behavioral effects of ethanol would be reduced more in the Q266I mutant than the M287L and found rotarod ataxia to be the behavior that fulfilled this criterion. Compared with controls, the mutant mice also differed in ethanol consumption, ethanol-stimulated startle response, signs of acute physical dependence, and duration of loss of righting response produced by ethanol, butanol, ketamine, pentobarbital, and flurazepam. Some of these behavioral changes were mimicked in wild-type mice by acute injections of low, subconvulsive doses of strychnine. Both mutants showed increased acoustic startle response and increased sensitivity to strychnine seizures. Thus, in addition to reducing ethanol action on the GlyRs, these mutations reduced glycinergic inhibition, which may also alter sensitivity to GABAergic drugs. PMID:22037202

TWRS Retrieval and Storage Mission and Immobilized Low Activity Waste (ILAW) Disposal Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

BURBANK, D.A.

This project plan has a twofold purpose. First, it provides a waste stream project plan specific to the River Protection Project (RPP) (formerly the Tank Waste Remediation System [TWRS] Project) Immobilized Low-Activity Waste (LAW) Disposal Subproject for the Washington State Department of Ecology (Ecology) that meets the requirements of Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) Milestone M-90-01 (Ecology et al. 1994) and is consistent with the project plan content guidelines found in Section 11.5 of the Tri-Party Agreement action plan (Ecology et al. 1998). Second, it provides an upper tier document that can be used as themore » basis for future subproject line-item construction management plans. The planning elements for the construction management plans are derived from applicable U.S. Department of Energy (DOE) planning guidance documents (DOE Orders 4700.1 [DOE 1992] and 430.1 [DOE 1995a]). The format and content of this project plan are designed to accommodate the requirements mentioned by the Tri-Party Agreement and the DOE orders. A cross-check matrix is provided in Appendix A to explain where in the plan project planning elements required by Section 11.5 of the Tri-Party Agreement are addressed.« less

NASA Ares 1 Crew Launch Vehicle Upper Stage Configuration Selection Process

NASA Technical Reports Server (NTRS)

Cook, Jerry R.

2006-01-01

The Upper Stage Element of NASA s Ares I Crew Launch Vehicle (CLV) is a "clean-sheet" approach that is being designed and developed in-house, with Element management at MSFC. The USE concept is a self-supporting cylindrical structure, approximately 115 long and 216" in diameter. While the Reusable Solid Rocket Booster (RSRB) design has changed since the CLV inception, the Upper Stage Element design has remained essentially a clean-sheet approach. Although a clean-sheet upper stage design inherently carries more risk than a modified design, it does offer many advantages: a design for increased reliability; built-in extensibility to allow for commonality/growth without major redesign; and incorporation of state-of-the-art materials, hardware, and design, fabrication, and test techniques and processes to facilitate a potentially better, more reliable system.

45 CFR 287.25 - May Tribes form a consortium to operate a NEW Program?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 2 2014-10-01 2012-10-01 true May Tribes form a consortium to operate a NEW... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Eligible Tribes § 287.25 May Tribes form a consortium to operate a NEW Program? (a) Yes, as long as each Tribe forming the consortium is an “eligible Indian tribe...

45 CFR 287.25 - May Tribes form a consortium to operate a NEW Program?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true May Tribes form a consortium to operate a NEW... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Eligible Tribes § 287.25 May Tribes form a consortium to operate a NEW Program? (a) Yes, as long as each Tribe forming the consortium is an “eligible Indian tribe...

45 CFR 287.25 - May Tribes form a consortium to operate a NEW Program?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 2 2012-10-01 2012-10-01 false May Tribes form a consortium to operate a NEW... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Eligible Tribes § 287.25 May Tribes form a consortium to operate a NEW Program? (a) Yes, as long as each Tribe forming the consortium is an “eligible Indian tribe...

75 FR 36348 - Opportunity for Designation in the Amarillo, TX; Cairo, IL; and State of North Carolina Areas

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-25

... by the southern Childress County line to the western Childress County line north to U.S. Route 287; U.S. Route 287 northwest to Donley County; the southern Donley and Armstrong County lines west to... . SUPPLEMENTARY INFORMATION: Section 7(f)(1) of the United States Grain Standards Act (USGSA) (7 U.S.C. 71-87k...

46 CFR 287.13 - Deposit of proceeds of sales or indemnities.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 8 2011-10-01 2011-10-01 false Deposit of proceeds of sales or indemnities. 287.13... sales or indemnities. (a) Manner of deposit. The deposit required by section 511 of the Act must be made... equal to the “net proceeds” of the sale, or the “net indemnity” for the loss. By “net proceeds” and “net...

40 CFR 437.46 - Pretreatment standards for existing sources (PSES)

Code of Federal Regulations, 2011 CFR

2011-07-01

....218 0.0662 Zinc 2.87 0.641 Organic Parameters Bis(2-ethylhexyl) phthalate 0.267 0.158 Carbazole 0.392... Titanium 0.0947 0.0618 Vanadium 0.218 0.0662 Zinc 2.87 0.641 Organic Parameters Bis(2-ethylhexyl) phthalate... Tin 0.249 0.146 Zinc 6.95 4.46 Organic Parameters Bis (2-ethylhexyl) phthalate 0.267 0.158 Carbazole 0...

New Law Relating to Family and Medical Leave (1987 Wisconsin Act 287). Information Memorandum 88-13.

ERIC Educational Resources Information Center

Rose, Laura

This document describes the 1987 Wisconsin Act 287 which concern providing family leave and medical leave to employees. The background of the law is described in the first part of the document. The second part of the document describes the family and medical leave act. These topics are covered: (1) basic provisions of family and medical leave,…

The Chronology and Petrogenesis of the Mare Basalt Clast from Lunar Meteorite Dhofar 287: Rb-Sr and Sm- Nd Isotopic Studies

NASA Technical Reports Server (NTRS)

Shih, C.-Y.; Nyquist, L. E.; Reese, Y.; Wiesmann, H.; Nazarov, M. A.; Taylor, L. A.

2002-01-01

The Sm-Nd isochron for lunar mare basalt meteorite Dhofar 287A yields T = 3.46 +/- 0.03 Ga and Nd = 0.6 +/- 0.3. Its Rb-Sr isotopic system is severely altered. The basalt is unique, probably coming from an enriched mantle source. Additional information is contained in the original extended abstract.

Projection of Patient Condition Code Distributions for Naval Combat Deployments

DTIC Science & Technology

1999-09-06

Helminthiasis 286 Pancreatitis 287 Cirrhosis 18.97% 13.03% Atlantic Pacific 12.0% 12.0% 12.0% 12.0% 12.0% 12.0% 12.0% 12.0% 1.0% 1.0% 1.0% 1.0... Helminthiasis 0.44% 0.55% 255 Migraine 0.00% 0.00% 256 Hemorrhoidal disease 4.17% 2.87% 258 Hypertension/essential 2.53% 1.67% 259 Ischemic heart/disease

CASK and CaMKII function in Drosophila memory

PubMed Central

Malik, Bilal R.; Hodge, James J. L.

2014-01-01

Calcium (Ca2+) and Calmodulin (CaM)-dependent serine/threonine kinase II (CaMKII) plays a central role in synaptic plasticity and memory due to its ability to phosphorylate itself and regulate its own kinase activity. Autophosphorylation at threonine 287 (T287) switches CaMKII to a Ca2+ independent and constitutively active state replicated by overexpression of a phosphomimetic CaMKII-T287D transgene or blocked by expression of a T287A transgene. A second pair of sites, T306 T307 in the CaM binding region once autophosphorylated, prevents CaM binding and inactivates the kinase during synaptic plasticity and memory, and can be blocked by a TT306/7AA transgene. Recently the synaptic scaffolding molecule called CASK (Ca2+/CaM-associated serine kinase) has been shown to control both sets of CaMKII autophosphorylation events during neuronal growth, Ca2+ signaling and memory in Drosophila. Deletion of either full length CASK or just its CaMK-like and L27 domains removed middle-term memory (MTM) and long-term memory (LTM), with CASK function in the α′/ß′ mushroom body neurons being required for memory. In a similar manner directly changing the levels of CaMKII autophosphorylation (T287D, T287A, or TT306/7AA) in the α′/ß′ neurons also removed MTM and LTM. In the CASK null mutant expression of either the Drosophila or human CASK transgene in the α′/ß′ neurons was found to completely rescue memory, confirming that CASK signaling in α′/β′ neurons is necessary and sufficient for Drosophila memory formation and that the neuronal function of CASK is conserved between Drosophila and human. Expression of human CASK in Drosophila also rescued the effect of CASK deletion on the activity state of CaMKII, suggesting that human CASK may also regulate CaMKII autophosphorylation. Mutations in human CASK have recently been shown to result in intellectual disability and neurological defects suggesting a role in plasticity and learning possibly via regulation of CaMKII autophosphorylation. PMID:25009461

Performance of a 1.15-pressure-ratio axial-flow fan stage with a blade tip solidity of 0.5

NASA Technical Reports Server (NTRS)

Osborn, W. M.; Steinke, R. J.

1974-01-01

The overall and blade-element performance of a low-solidity, low-pressure-ratio, low-tip-speed fan stage is presented over the stable operating range at rotative speeds from 90 to 120 percent of design speed. At design speed a stage peak efficiency of 0.836 was obtained at a weight flow of 30.27 kilograms per second and a pressure ratio of 1.111. The pressure ratio was less than design pressure ratio, and the design energy input into the rotor was not achieved. A mismatch of the rotor and stator blade elements resulted due to the lower than design pressure ratio of the rotor.

Development of high sensitivity eight-element multiplexed fiber laser acoustic pressure hydrophone array and interrogation system

NASA Astrophysics Data System (ADS)

Li, Ming; Sun, Zhihui; Zhang, Xiaolei; Li, Shujuan; Song, Zhiqiang; Wang, Meng; Guo, Jian; Ni, Jiasheng; Wang, Chang; Peng, Gangding; Xu, Xiangang

2017-09-01

Fiber laser hydrophones have got widespread concerns due to the unique advantages and broad application prospects. In this paper, the research results of the eight-element multiplexed fiber laser acoustic pressure array and the interrogation system are introduced, containing low-noise distributed feedback fiber laser (DFB-FL) fabrication, sensitivity enhancement packaging, and interferometric signal demodulation. The frequency response range of the system is 10Hz-10kHz, the laser frequency acoustic pressure sensitivity reaches 115 dB re Hz/Pa, and the equivalent noise acoustic pressure is less than 60μPa/Hz1/2. The dynamic range of the system is greater than 120 dB.

STUDIES OF RADIO CONTAMINATION OF FOOD STUFFS EFFECTED BY ATOMIC OR HYDROGEN BOMB EXPLOSION. IX. RADIO CHEMICAL ANALYSIS OF RADIO CONTAMINATED FISH LIVERS IN 1958 (in Japanese)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nagasawa, K.; Kasida, Y.; Kametani, K.

The contamination in 224 livers of tunny and sword fish caught in the Pacific 0cean was examined. As a result of radiochemical analysis in the four samples Fe/sup 59/ Zn/sup 65/, Sr/sup 90/, Y/sup 90/, and Cd/sup 115m/ were identified. The maximum concentrations of the elements determined were Fe/sup 59/ , 1.58 x l0/sup -4/ mu c; Zn/sup 65/, 4.58 x 10/sup -3/ mu c; Sr/sup 90/ and Y/ sup 90/, 8. 33 x 10/sup -7/ mu c; and Cd/sup 115m/, 3.66 x l0/sup -4/ mu c. When 10 g of wet sample was assumed to be the daily personalmore » intake dose, these were less than the maximum permissible concentrations. (auth)« less

The Republic of Macedonia: Implementing the Ohrid Framework Agreement and Reforming the State

DTIC Science & Technology

2008-09-01

that included members of the goverment . • The “capacity building/weakening’ school. Argument is the organized crime elements united and recruited...115 Republic of Macedonia State Statistical Office, Tourism in the Republic of Macedonia, http://www.stat.gov.mk/english/statistiki_eng.asp?ss...essential for improving the economy. The ROM must invest wisely the funds received by the EU towards infrastructure, business development and tourism

Soluble and filamentous proteins in Arabidopsis sieve elements.

PubMed

Batailler, Brigitte; Lemaître, Thomas; Vilaine, Françoise; Sanchez, Christian; Renard, Denis; Cayla, Thibaud; Beneteau, Julie; Dinant, Sylvie

2012-07-01

Phloem sieve elements are highly differentiated cells involved in the long-distance transport of photoassimilates. These cells contain both aggregated phloem-proteins (P-proteins) and soluble proteins, which are also translocated by mass flow. We used liquid chromatography-tandem mass spectrometry (LC-MS/MS) to carry out a proteomic survey of the phloem exudate of Arabidopsis thaliana, collected by the ethylenediaminetetraacetic acid (EDTA)-facilitated method. We identified 287 proteins, a large proportion of which were enzymes involved in the metabolic precursor generation and amino acid synthesis, suggesting that sieve tubes display high levels of metabolic activity. RNA-binding proteins, defence proteins and lectins were also found. No putative P-proteins were detected in the EDTA-exudate fraction, indicating a lack of long-distance translocation of such proteins in Arabidopsis. In parallel, we investigated the organization of P-proteins, by high-resolution transmission electron microscopy, and the localization of the phloem lectin PP2, a putative P-protein component, by immunolocalization with antibodies against PP2-A1. Transmission electron microscopy observations of P-proteins revealed bundles of filaments resembling strings of beads. PP2-A1 was found weakly associated with these structures in the sieve elements and bound to plastids. These observations suggest that PP2-A1 is anchored to P-proteins and organelles rather than being a structural component of P-proteins. © 2012 Blackwell Publishing Ltd.

78 FR 61386 - Hewlett Packard Company, AMS Call Center-Conway, CSS-Americas Support (AMSS) Division, Personal...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-03

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-82,287; TA-W-82,287A] Hewlett... accordance with Section 223 of the Trade Act of 1974, as amended (``Act''), 19 U.S.C. 2273, the Department of... assistance if they satisfy the criteria of subsection (a), (b) or (e) of Section 222 of the Act, 19 U.S.C...

78 FR 68146 - Notice of Application for Approval of Discontinuance or Modification of a Railroad Signal System

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-13

..., GA 30309. NS seeks approval of the proposed discontinuance of Control Point (CP) Oak and the discontinuance of the traffic control system (TCS) between CP Maumee, Milepost (MP) DY 1.2/CD 287.65, and Stanley... discontinued on the Oakdale Connection Track between CP 286, MP XA 286.90/CD 286.75, and CP Oak, MP XA 287.80...

Arsenic and other elements in drinking water and dietary components from the middle Gangetic plain of Bihar, India: Health risk index.

PubMed

Kumar, Manoj; Rahman, Mohammad Mahmudur; Ramanathan, A L; Naidu, Ravi

2016-01-01

This study investigates the level of contamination and health risk assessment for arsenic (As) and other elements in drinking water, vegetables and other food components in two blocks (Mohiuddinagar and Mohanpur) from the Samastipur district, Bihar, India. Groundwater (80%) samples exceeded the World Health Organization (WHO) guideline value (10μg/L) of As while Mn exceeded the previous WHO limit of 400μg/L in 28% samples. The estimated daily intake of As, Cd, Co, Cr, Cu, Mn, Ni, Pb and Zn from drinking water and food components were 169, 19, 26, 882, 4645, 14582, 474, 1449 and 12,955μg, respectively (estimated exposure 3.70, 0.41, 0.57, 19.61, 103.22, 324.05, 10.53, 32.21 and 287.90μg per kg bw, respectively). Twelve of 15 cooked rice contained high As concentration compared to uncooked rice. Water contributes (67%) considerable As to daily exposure followed by rice and vegetables. Whereas food is the major contributor of other elements to the dietary exposure. Correlation and principal component analysis (PCA) indicated natural source for As but for other elements, presence of diffused anthropogenic activities were responsible. The chronic daily intake (CDI) and health risk index (HRI) were also estimated from the generated data. The HRI were >1 for As in drinking water, vegetables and rice, for Mn in drinking water, vegetables, rice and wheat, for Pb in rice and wheat indicated the potential health risk to the local population. An assessment of As and other elements of other food components should be conducted to understand the actual health hazards caused by ingestion of food in people residing in the middle Gangetic plain. Copyright © 2015 Elsevier B.V. All rights reserved.

Evaluation of Populus and Salix continuously irrigated with landfill leachate I. Genotype-specific elemental phytoremediation.

PubMed

Zalesny, Ronald S; Bauer, Edmund O

2007-01-01

There is a need for the identification and selection of specific tree genotypes that can sequester elements from contaminated soils, with elevated rates of uptake. We irrigated Populus (DN17, DN182, DN34, NM2, NM6) and Salix (94003, 94012, S287, S566, SX61) genotypes planted in large soil-filled containers with landfill leachate or municipal water and tested for differences in inorganic element concentrations (P, K, Ca, Mg, S, Zn, B, Mn, Fe, Cu, Al, Na, and Cl) in the leaves, stems, and roots. Trees were irrigated with leachate or water during the final 12 wk of the 18-wk study. Genotype-specific uptake existed. For genera, tissue concentrations exhibited four responses. First, Populus had the greatest uptake of P, K, S, Cu, and Cl. Second, Salix exhibited the greatest uptake of Zn, B, Fe, and Al. Third, Salix had greater concentrations of Ca and Mg in leaves, while Populus had greater concentrations in stems and roots. Fourth, Populus had greater concentrations of Mn and Na in leaves and stems, while Salix had greater concentrations in roots. Populus deltoides x P. nigra clones exhibited better overall phytoremediation than the P. nigra x P. maximowiczii genotypes tested. Phytoremediation for S. purpurea clones 94003 and 94012 was generally less than for other Salix genotypes. Overall, concentrations of elements in the leaves, stems, and roots corroborated those in the plant-sciences literature. Uptake was dependent upon the specific genotype for most elements. Our results corroborated the need for further testing and selecting of specific clones for various phytoremediation needs, while providing a baseline for future researchers developing additional studies and resource managers conducting on-site remediation.

Soil contamination with emissions of non-ferrous metallurgical plants

NASA Astrophysics Data System (ADS)

Vodyanitskii, Yu. N.; Plekhanova, I. O.; Prokopovich, E. V.; Savichev, A. T.

2011-02-01

The upper soil horizons are strongly contaminated in the area influenced by the Mid-Urals copper smelter. In the technogenic desert and impact zones, the contents of a number of elements (Cu, Zn, As, Pb, P, and S) by many times exceed their clarke values and the maximum permissible concentrations (or provisional permissible concentrations). The degree of technogeneity (Tg) for these elements is very high in these zones. In the far buffer zone, Tg is about zero for many elements and increases up to Tg = 27-42% for four heavy elements (Cu, Zn, Pb, and As) and up to 81-98% for P and S. The buffer capacity of the humus horizon depends on the soil's location within the technogeochemical anomaly and also on the particular pollutant. In the impact zone, it is equal to 70-77% for lead and arsenic, although other technogenic elements (Zn, Cr, S, and P) are poorly retained and readily migrate into the deeper horizons (the buffer capacity is equal to 14-25%). Nearly all the heavy metals enter the soil in the form of sulfides. The soils in the area affected by the Noril'sk mining and smelting metallurgical enterprise are subdivided into two groups according to the degree of their contamination, i.e., the soils within Noril'sk proper and the soils in its suburbs to a distance of 4-15 km. The strongest soil contamination is recorded in the city: the clarke values are exceeded by 287, 78, 16, 4.1, and 3.5 times for Cu, Ni, Cr, Fe, and S, respectively. The major pollutants enter the soil from the ferruginous slag. The soil's contamination degree is lower in the suburbs, where heavy metal sulfides reach the soils with the aerial emission from the enterprise.

A Petrogenetic Evaluation of Clinopyroxene-hosted Melt Inclusions from an Enriched Submarine Lava of the Samoan Hotspot Track: A Phase Equilibria and Diffusion Modeling Study

NASA Astrophysics Data System (ADS)

Adams, J.; Spera, F. J.; Jackson, M. G.; Schmidt, J.

2017-12-01

The Samoan hotspot track hosts lavas that are representative of the Enriched Mantle II (EMII) geochemical signature, long thought to result from incorporation of recycled upper continental crust. Silicic (66-69 wt% SiO2) clinopyroxene (cpx)-hosted melt inclusions (MI) from isotopically enriched lavas from Samoa provide a window into their petrogenetic evolution. Enriched Samoan submarine lava, ALIA-115-18, from Savai'i Island, Samoa contains clinopyroxene (cpx) antecrysts that host uniformly trachydacitic MI's. The cpx's are more radiogenic (87Sr/86Sr=0.720232-0.720830) than the host whole rock (WR) (87Sr/86Sr=0.718592) providing evidence of cpx antecryst-WR disequilibrium (Jackson et al., 2007, 2009). Phase equilibria calculations using the Magma Chamber Simulator (Bohrson et al., 2014) have corroborated a lack of relationship by fractional crystallization (FC) between the antecrysts and WR composition as well as the cpx's and MI's. Cpx thermobarometry reveals cpx antecryst-WR disequilibrium is not a pressure effect but rather reflects cpx crystallization from a more magnesian parental melt (similar to the most mafic WR of the Samoan submarine lavas; SiO2=49 wt%, MgO=9 wt%), different than the ALIA-115-18 WR. The cpx antecrysts (Mg#72-86), and the rest of the antecryst population show a crystallization range of 1-5 kbar. Cpx groundmass phenocrysts (Mg#70-75) are consistent with ALIA-115-18 WR (SiO2=55 wt%, MgO=5 wt%) composition by FC in the 1-5 kbar range. The more mafic parent may represent the magma that mixed with evolved magmas, giving rise to radiogenic ALIA-115-18, and possibly the silicic MI's. Thus, studying the petrogenesis of the MI's is essential to understanding the evolution of EMII. Many cpx antecrysts with MI's are characterized by compositional halos; transects across the halos exhibit major and trace element gradients. Modeling of diffusive exchange (Cottrell et al., 2002) between the MI's and their host lavas, mediated by diffusion through cpx, allows one to constrain post-entrapment timescales. Preliminary results show distinct gradients in Al, Ti, Si, Cr, Sr, Zr, and the REEs. These elements cover a wide range of diffusivities and partition coefficients enabling a detailed timescale study of post-entrapment MI evolution and the petrogenesis of the Samoan lava suite.

Multifunctional Beta Ti Alloy with Improved Specific Strength

NASA Astrophysics Data System (ADS)

Park, Chan Hee; Hong, Jae-Keun; Lee, Sang Won; Yeom, Jong-Taek

2017-12-01

Gum metals feature properties such as ultrahigh strength, ultralow elastic modulus, superelasticity, and superplasticity. They are composed of elements from Groups 4 and 5 of the periodic table and exist when the valance electron concentration (\\overline{e/a}) is 4.24; the bond order (\\overline{Bo}) is 2.87; and the "d" electron-orbital energy level (\\overline{Md}) is 2.45 eV. Typical compositions include Ti-23Nb-2Zr-0.7Ta-O and Ti-12Ta-9Nb-6Zr-3 V-O, which contain large amounts of heavy Group-5 elements such as Nb and Ta. In the present study, to improve the specific strength of a multifunctional beta Ti alloy, three alloys (Ti-20Nb-5Zr-1Fe-O, Ti-12Zr-10Mo-4Nb-O, and Ti-24Zr-9Cr-3Mo-O) were designed by satisfying the above three requirements while adding Fe, Mo, and Cr, which are not only lightweight but also have strong hardening effects. Microstructural and mechanical property analyses revealed that Ti-20Nb-5Zr-1Fe-O has a 25% higher specific strength than gum metal while maintaining an ultralow elastic modulus.

Accuracy improvement of quantitative analysis by spatial confinement in laser-induced breakdown spectroscopy.

PubMed

Guo, L B; Hao, Z Q; Shen, M; Xiong, W; He, X N; Xie, Z Q; Gao, M; Li, X Y; Zeng, X Y; Lu, Y F

2013-07-29

To improve the accuracy of quantitative analysis in laser-induced breakdown spectroscopy, the plasma produced by a Nd:YAG laser from steel targets was confined by a cavity. A number of elements with low concentrations, such as vanadium (V), chromium (Cr), and manganese (Mn), in the steel samples were investigated. After the optimization of the cavity dimension and laser fluence, significant enhancement factors of 4.2, 3.1, and 2.87 in the emission intensity of V, Cr, and Mn lines, respectively, were achieved at a laser fluence of 42.9 J/cm(2) using a hemispherical cavity (diameter: 5 mm). More importantly, the correlation coefficient of the V I 440.85/Fe I 438.35 nm was increased from 0.946 (without the cavity) to 0.981 (with the cavity); and similar results for Cr I 425.43/Fe I 425.08 nm and Mn I 476.64/Fe I 492.05 nm were also obtained. Therefore, it was demonstrated that the accuracy of quantitative analysis with low concentration elements in steel samples was improved, because the plasma became uniform with spatial confinement. The results of this study provide a new pathway for improving the accuracy of quantitative analysis of LIBS.

New Fragment Separation Technology for Superheavy Element Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shaughnessy, D A; Moody, K J; Henderson, R A

2008-01-28

This project consisted of three major research areas: (1) development of a solid Pu ceramic target for the MASHA separator, (2) chemical separation of nuclear decay products, and (3) production of new isotopes and elements through nuclear reactions. There have been 16 publications as a result of this project, and this collection of papers summarizes our accomplishments in each of the three areas of research listed above. The MASHA (Mass Analyzer for Super-Heavy Atoms) separator is being constructed at the U400 Cyclotron at the Flerov Laboratory of Nuclear Reactions in Dubna, Russia. The purpose of the separator is to physicallymore » separate the products from nuclear reactions based on their isotopic masses rather than their decay characteristics. The separator was designed to have a separation between isotopic masses of {+-}0.25 amu, which would enable the mass of element 114 isotopes to be measured with outstanding resolution, thereby confirming their discovery. In order to increase the production rate of element 114 nuclides produced via the {sup 244}Pu+{sup 48}Ca reaction, a new target technology was required. Instead of a traditional thin actinide target, the MASHA separator required a thick, ceramic-based Pu target that was thick enough to increase element 114 production while still being porous enough to allow reaction products to migrate out of the target and travel through the separator to the detector array located at the back end. In collaboration with UNLV, we began work on development of the Pu target for MASHA. Using waste-form synthesis technology, we began by creating zirconia-based matrices that would form a ceramic with plutonium oxide. We used samarium oxide as a surrogate for Pu and created ceramics that had varying amounts of the starting materials in order to establish trends in material density and porosity. The results from this work are described in more detail in Refs. [1,4,10]. Unfortunately, work on MASHA was delayed in Russia because it was found that the efficiency of transporting products from the target chamber to the detector array was much too low for applications in heavy element experiments where production rates are on the order of one atom per day or less. Work continues on the MASHA separator, and once the efficiency has been improved, we plan to continue our work on the Pu target for future element 114 experiments. Due to the delays of the MASHA separator, work on establishing the identity of heavy element species produced through nuclear reactions focused instead on chemical separations. In particular, element 115 decays through a series of alpha decays, terminating with an element 105 isotope with a long half-life ({approx} 1 day). By chemically separating the element 105 daughter and observing its subsequent fission decay, the identity of the original parent nucleus can be established through the genetic correlation of the initial series of alpha decays. Chemical separations of element 105 were developed in Switzerland, Russia, and at LLNL. Over the course of two experiments, reaction products from the {sup 243}Am+{sup 48}Ca reaction were collected in a copper block and subsequently processed for chemical separation of the Group Five elements [8,9,13,15]. The Group Five elements were initially separated from the Group Four species, and then the samples were sub-divided into tantalum and niobium fractions. All of the fission events were observed in the tantalum fractions, which implied that element 105 behaved more like tantalum under the chemical conditions of these experiments. These experiments were very successful, and not only demonstrated that chemical separation could be performed on single atoms of interest, but also lent proof to the identity of the parent nucleus as element 115. Subsequent analysis of the alpha spectra taken during the experiment further prove that the fission events observed during the two experiments came from element 105 as the decay daughter of element 115 and could not attributed to interference from other background species [16]. The final aspect of this project was the production of new isotopes and elements. All of the experiments were performed in Dubna at the U400 Cyclotron and the results are described in more detail in Refs. [2,3,5-8,11,12,14]. The first experiments were designed to establish the decay properties of isotopes of elements 112, 114, and 116 [5]. Because these isotopic signatures were established through these initial experiments, the discovery of element 118 [11] was possible, since the 118 nuclides decayed into these previously studied isotopes. This was the first successful report of the discovery of element 118, which was reported by the media to a large extent. The last experiment that was performed for this project was the production and detection of a new isotope of element 113 [14].« less

Very high energy observations of the BL Lac objects 3C 66A and OJ 287

NASA Astrophysics Data System (ADS)

Lindner, T.; Hanna, D. S.; Kildea, J.; Ball, J.; Bramel, D. A.; Carson, J.; Covault, C. E.; Driscoll, D.; Fortin, P.; Gingrich, D. M.; Jarvis, A.; Mueller, C.; Mukherjee, R.; Ong, R. A.; Ragan, K.; Scalzo, R. A.; Williams, D. A.; Zweerink, J.

2007-11-01

Using the Solar Tower Atmospheric Cherenkov Effect Experiment (STACEE), we have observed the BL Lac objects 3C 66A and OJ 287. These are members of the class of low-frequency-peaked BL Lac objects (LBLs) and are two of the three LBLs predicted by Costamante and Ghisellini [L. Costamante, G. Ghisellini, Astron. Astrophys. 384 (2002) 56] to be potential sources of very high energy (>100 GeV) gamma-ray emission. The third candidate, BL Lacertae, has recently been detected by the MAGIC collaboration [J. Albert et al., arXiv:astro-ph/0703084v1 (2007)]. Our observations have not produced detections; we calculate a 99% CL upper limit of flux from 3C 66A of 0.15 Crab flux units and from OJ 287 our limit is 0.52 Crab. These limits assume a Crab-like energy spectrum with an effective energy threshold of 185 GeV.

Dance of Two Monster Black Holes

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2016-03-01

This past December, researchers all over the world watched an outburst from the enormous black hole in OJ 287 an outburst that had been predicted years ago using the general theory of relativity.Outbursts from Black-Hole OrbitsOJ 287 is one of the largest supermassive black holes known, weighing in at 18 billion solar masses. Located about 3.5 billion light-years away, this monster quasar is bright enough that it was first observed as early as the 1890s. What makes OJ 287 especially interesting, however, is that its light curve exhibits prominent outbursts roughly every 12 years.Diagram illustrating the orbit of the secondary black hole (shown in blue) in OJ 287 from 2000 to 2023. We see outbursts (the yellow bubbles) every time the secondary black hole crosses the accretion disk (shown in red, ina side view) surrounding the primary (the black circle). [Valtonen et al. 2016]What causes the outbursts? Astronomers think that there is a second supermassive black hole, ~100 times smaller, inspiraling as it orbits the central monster and set to merge within the next 10,000 years. In this model, the primary black hole of OJ 287 is surrounded by a hot accretion disk. As the secondary black hole orbits the primary, it regularly punches through this accretion disk, heating the material and causing the release of expanding bubbles of hot gas pulled from the disk. This gas then radiates thermally, causing the outbursts we see.Attempts to model this scenario using Newtonian orbits all fail; the timing of the secondary black holes crossings through the accretion disk (as measured by when we see the outbursts) can only be explained by a model incorporating general-relativistic effects on the orbit. Careful observations and precise timing of these outbursts therefore provide an excellent test of general relativity.Watching a Predicted CrossingThe model of OJ 287 predicted another disk crossing in December 2015, so professional and amateur astronomers around the world readied more than two dozen ground-based optical telescopes and the Swift/XRT satellite to observe OJ 287 in this time frame. The outburst occurred right on schedule, peaking on 5 December 2015, and the results of the observing campaign are now presented in a study led by Mauri Valtonen (University of Turku).Optical photometry of OJ 287 from October to December 2015, showing the outburst that resulted from the secondary black hole crossing the disk. [Valtonen et al. 2016]Because the secondary black holes orbit is affected by the spin of the primary black hole, Valtonen and collaborators were able to use the timing of the outburst to measure the spin of OJ 287s primary black hole to remarkably high precision. They find that its Kerr parameter is 0.313 0.01 which means its spinning at about a third of the maximum rate allowed by general relativity.The outburst timing also confirmed several general-relativistic properties of the system, including its loss of energy to gravitational waves. Remarkably, the energy lost as the secondary black hole punches through the accretion disk is still ten thousand times smaller than the amount of energy it loses through gravitational waves!The observations from this outburst have provided important black-hole measurements and tests of general relativity which are especially relevant in this new era of gravitational wave detections. And we may be able to perform still more tests on the secondarys next pass through the disk, which should occur in 2019.BonusCheck out this awesome animation of the orbits in a system similar to OJ 287! The secondarys orbit precesses around the primary due to general-relativistic effects. The sound you hearis an audio representation of the increasing frequency as the two black holes inspiral. You can find more information about this animation here. [Steve Drasco Curt Cutler]CitationM. J. Valtonen et al 2016 ApJ 819 L37. doi:10.3847/2041-8205/819/2/L37

Bias assessment of lower and middle tropospheric CO2 concentrations of GOSAT/TANSO-FTS TIR version 1 product

NASA Astrophysics Data System (ADS)

Saitoh, Naoko; Kimoto, Shuhei; Sugimura, Ryo; Imasu, Ryoichi; Shiomi, Kei; Kuze, Akihiko; Niwa, Yosuke; Machida, Toshinobu; Sawa, Yousuke; Matsueda, Hidekazu

2017-10-01

CO2 observations in the free troposphere can be useful for constraining CO2 source and sink estimates at the surface since they represent CO2 concentrations away from point source emissions. The thermal infrared (TIR) band of the Thermal and Near Infrared Sensor for Carbon Observation (TANSO) Fourier transform spectrometer (FTS) on board the Greenhouse Gases Observing Satellite (GOSAT) has been observing global CO2 concentrations in the free troposphere for about 8 years and thus could provide a dataset with which to evaluate the vertical transport of CO2 from the surface to the upper atmosphere. This study evaluated biases in the TIR version 1 (V1) CO2 product in the lower troposphere (LT) and the middle troposphere (MT) (736-287 hPa), on the basis of comparisons with CO2 profiles obtained over airports using Continuous CO2 Measuring Equipment (CME) in the Comprehensive Observation Network for Trace gases by AIrLiner (CONTRAIL) project. Bias-correction values are presented for TIR CO2 data for each pressure layer in the LT and MT regions during each season and in each latitude band: 40-20° S, 20° S-20° N, 20-40° N, and 40-60° N. TIR V1 CO2 data had consistent negative biases of 1-1.5 % compared with CME CO2 data in the LT and MT regions, with the largest negative biases at 541-398 hPa, partly due to the use of 10 µm CO2 absorption band in conjunction with 15 and 9 µm absorption bands in the V1 retrieval algorithm. Global comparisons between TIR CO2 data to which the bias-correction values were applied and CO2 data simulated by a transport model based on the Nonhydrostatic ICosahedral Atmospheric Model (NICAM-TM) confirmed the validity of the bias-correction values evaluated over airports in limited areas. In low latitudes in the upper MT region (398-287 hPa), however, TIR CO2 data in northern summer were overcorrected by these bias-correction values; this is because the bias-correction values were determined using comparisons mainly over airports in Southeast Asia, where CO2 concentrations in the upper atmosphere display relatively large variations due to strong updrafts.

40 CFR 437.46 - Pretreatment standards for existing sources (PSES).

Code of Federal Regulations, 2013 CFR

2013-07-01

....409 0.120 Titanium 0.0947 0.0618 Vanadium 0.218 0.0662 Zinc 2.87 0.641 Organic Parameters Bis(2... 1.45 Silver 0.120 0.0351 Tin 0.409 0.120 Titanium 0.0947 0.0618 Vanadium 0.218 0.0662 Zinc 2.87 0... Lead 1.32 0.283 Mercury 0.00234 0.000739 Nickel 3.95 1.45 Silver 0.120 0.0351 Tin 0.409 0.120 Titanium...

Strategic Forum. Number 287, May 2014. Strategy and Force Planning in a Time of Austerity

DTIC Science & Technology

2014-05-01

ceiling crisis with the Budget Control Act of 2011, which prescribed sequestration. Sequestration was viewed as so draconian and antistrategic that...reductions, and proposed reductions to military compensation, the SCMR identified, but did not decide between, two broad options going for- ward, each of...years 1970–2013 (hereafter EROP); and Congressional Budget Office (CBO), Budget 8 SF No. 287 ndupress.ndu.edu The Center for Strategic Research ( CSR

Testis sparing surgery for treatment of small testicular lesions: Is it feasible even in germ cell tumors?

PubMed

Bojanic, Nebojsa; Bumbasirevic, Uros; Bojanic, Gordana; Vukovic, Ivan; Milojevic, Bogomir; Pekmezovic, Tatjana

2017-03-01

To evaluate the results of testis-sparing surgery (TSS) in patients, with small testicular lesions and a normal contralateral testicle. In all, 28 patients were treated with TSS for small testicular lesions and a normal contralateral testicle. TSS was considered in patients with testicular lesions smaller than 2 cm and no evidence of metastatic disease. The mean age of patients was 35.3 ± 7.3 years, while the mean diameter of the testicular lesions was 11.4 ± 3.7 mm. After pathological examination, 18 patients (64.3%) were diagnosed with stromal tumors and miscellaneous lesions, while 10 (35.7%) had a germ cell tumor. The median follow-up time for the former group was 33 months and no recurrences were observed. In one patient with germ cell tumor, immediate orchiectomy was performed, while the remaining nine were followed-up (median time, 45 months). One patient developed local recurrence after 39 months. Excellent outcomes for benign lesions could be achieved using TSS. TSS could be offered safely in highly selected patients with germ cell tumors, specifically within a clinical trial but there is more data needed regarding the potential risks and benefits. J. Surg. Oncol. 2017;115:287-290. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Glycotoxin and Autoantibodies Are Additive Environmentally Determined Predictors of Type 1 Diabetes

PubMed Central

Beyan, Huriya; Riese, Harriette; Hawa, Mohammed I.; Beretta, Guisi; Davidson, Howard W.; Hutton, John C.; Burger, Huibert; Schlosser, Michael; Snieder, Harold; Boehm, Bernhard O.; Leslie, R. David

2012-01-01

In type 1 diabetes, diabetes-associated autoantibodies, including islet cell antibodies (ICAs), reflect adaptive immunity, while increased serum Nε-carboxymethyl-lysine (CML), an advanced glycation end product, is associated with proinflammation. We assessed whether serum CML and autoantibodies predicted type 1 diabetes and to what extent they were determined by genetic or environmental factors. Of 7,287 unselected schoolchildren screened, 115 were ICA+ and were tested for baseline CML and diabetes autoantibodies and followed (for median 7 years), whereas a random selection (n = 2,102) had CML tested. CML and diabetes autoantibodies were determined in a classic twin study of twin pairs discordant for type 1 diabetes (32 monozygotic, 32 dizygotic pairs). CML was determined by enzyme-linked immunosorbent assay, autoantibodies were determined by radioimmunoprecipitation, ICA was determined by indirect immunofluorescence, and HLA class II genotyping was determined by sequence-specific oligonucleotides. CML was increased in ICA+ and prediabetic schoolchildren and in diabetic and nondiabetic twins (all P < 0.001). Elevated levels of CML in ICA+ children were a persistent, independent predictor of diabetes progression, in addition to autoantibodies and HLA risk. In twins model fitting, familial environment explained 75% of CML variance, and nonshared environment explained all autoantibody variance. Serum CML, a glycotoxin, emerged as an environmentally determined diabetes risk factor, in addition to autoimmunity and HLA genetic risk, and a potential therapeutic target. PMID:22396204

Job Demands & Pesticide Exposure among Immigrant Latino Farmworkers

PubMed Central

Grzywacz, Joseph G.; Quandt, Sara A.; Vallejos, Quirina M.; Whalley, Lara E.; Chen, Haiying; Isom, Scott; Barr, Dana B.; Arcury, Thomas A.

2010-01-01

The goal of this study was to understand the potential threat of job stressors to farmworker health. To accomplish this goal we studied pesticide exposure, an issue with immediate and long-term health consequences, and predictions from the demands-control model of occupational stress. Longitudinal, self-report data and urine samples were collected at monthly intervals from a cohort of Latino farmworkers (N=287) during the 2007 agricultural season. The primary hypothesis was that greater exposure to psychological demands, physical exertion, and hazardous work conditions are associated with greater odds of detecting DAP urinary pesticide metabolites, biomarkers indicating exposure to pesticides. Contrary to this hypothesis, results indicated that none of the elements of the Demands-Control model were independently associated with detection of DAP urinary pesticide metabolites. However, analyses produced several interaction effects, including evidence that high levels of control may buffer the effects of physical job demands on detection of DAP urinary pesticide metabolites. PMID:20604632

Postnatal Changes in K+/Cl- Cotransporter-2 Expression in the Forebrain of Mice Bearing a Mutant Nicotinic Subunit Linked to Sleep-Related Epilepsy.

PubMed

Amadeo, Alida; Coatti, Aurora; Aracri, Patrizia; Ascagni, Miriam; Iannantuoni, Davide; Modena, Debora; Carraresi, Laura; Brusco, Simone; Meneghini, Simone; Arcangeli, Annarosa; Pasini, Maria Enrica; Becchetti, Andrea

2018-06-24

The Na + /K + /Cl - cotransporter-1 (NKCC1) and the K + /Cl - cotransporter-2 (KCC2) set the transmembrane Cl - gradient in the brain, and are implicated in epileptogenesis. We studied the postnatal distribution of NKCC1 and KCC2 in wild-type (WT) mice, and in a mouse model of sleep-related epilepsy, carrying the mutant β2-V287L subunit of the nicotinic acetylcholine receptor (nAChR). In WT neocortex, immunohistochemistry showed a wide distribution of NKCC1 in neurons and astrocytes. At birth, KCC2 was localized in neuronal somata, whereas at subsequent stages it was mainly found in the somatodendritic compartment. The cotransporters' expression was quantified by densitometry in the transgenic strain. KCC2 expression increased during the first postnatal weeks, while the NKCC1 amount remained stable, after birth. In mice expressing β2-V287L, the KCC2 amount in layer V of prefrontal cortex (PFC) was lower than in the control littermates at postnatal day 8 (P8), with no concomitant change in NKCC1. Consistently, the GABAergic excitatory to inhibitory switch was delayed in PFC layer V of mice carrying β2-V287L. At P60, the amount of KCC2 was instead higher in mice bearing the transgene. Irrespective of genotype, NKCC1 and KCC2 were abundantly expressed in the neuropil of most thalamic nuclei since birth. However, KCC2 expression decreased by P60 in the reticular nucleus, and more so in mice expressing β2-V287L. Therefore, a complex regulatory interplay occurs between heteromeric nAChRs and KCC2 in postnatal forebrain. The pathogenetic effect of β2-V287L may depend on altered KCC2 amounts in PFC during synaptogenesis, as well as in mature thalamocortical circuits. Copyright © 2018. Published by Elsevier Ltd.

Influence of interstitial V on structure and properties of ferecrystalline ([SnSe]{sub 1.15}){sub 1}(V{sub 1+x}Se{sub 2})n for n=1, 2, 3, 4, 5, and 6

DOE Office of Scientific and Technical Information (OSTI.GOV)

Falmbigl, M.; Putzky, D.; Ditto, J.

2015-11-15

A series of ferecrystalline compounds ([SnSe]{sub 1.15}){sub 1}(V{sub 1+x}Se{sub 2}){sub n} with n=1–6 and a thin film V{sub 1+x}Se{sub 2} were synthesized utilizing the modulated elemental reactant technique. The effect of interstitial V-atoms ranging from 0.13≤x≤0.42 in different compounds on structure and electrical properties of these intergrowth compounds is reported. The presence of the interstitial V-atoms for n>1 was confirmed by Rietveld refinements as well as HAADF-STEM cross sections. The off-stoichiometry in the thin film V{sub 1.13}Se{sub 2} causes a suppression of the charge density wave, similar to the effect of non-stoichiometry observed for the bulk compound. The charge densitymore » wave of ([SnSe]{sub 1.15}){sub 1}(V{sub 1+x}Se{sub 2}){sub 1,} however, is not affected by the non-stoichiometry due to its incorporation as volume inclusions or due to the quasi 2-dimensionality of the isolated VSe{sub 2} layer. In the compounds ([SnSe]{sub 1.15}){sub 1}(V{sub 1+x}Se{sub 2}){sub n} with n=2–6, the temperature dependence of the electrical resistivity approaches bulk-like behavior. - Highlights: • Ferecrystalline thin film compounds with interstitial V-atoms were synthesized. • Interstitial atoms cause an expansion of the superlattice. • The charge density wave transition in the V{sub 1.13}VSe{sub 2} film is strongly suppressed. • Interstitial V has a minor influence on the CDW transition of the ferecrystals.« less

High Frequency Ultrasound Array Designed for Ultrasound Guided Breast Biopsy

PubMed Central

Cummins, Thomas; Eliahoo, Payam; Shung, K. Kirk

2016-01-01

This paper describes the development of a miniaturized high frequency linear array that can be integrated within a core biopsy needle to improve tissue sampling accuracy during breast cancer biopsy procedures. The 64 element linear array has an element width of 14 μm, kerf width of 6 μm, element length of 1 mm and element thickness of 24 μm. The 2–2 array composite was fabricated using deep reactive ion etching of PMN-PT single crystal material. The array composite fabrication process as well as a novel high density electrical interconnect solution are presented and discussed. Array performance measurements show that the array had a center frequency and fractional bandwidth (−6 dB) of 59.1 MHz and 29.4%, respectively. Insertion loss and adjacent element cross talk at the center frequency were −41.0 dB and −23.7 dB, respectively. A B-mode image of a tungsten wire target phantom was captured using a synthetic aperture imaging system and the imaging test results demonstrate axial and lateral resolutions of 33.2 μm and 115.6 um, respectively. PMID:27046895

Reciprocity Calibration in a Plane Wave Resonator.

DTIC Science & Technology

1985-12-01

300 N. Quincy St. (code 11121ELEMENT NO INO :4NO ACCESS~oN NO Arlington, Va. , zip. 22217 6 115 3N IR1108-0 384_-1 8 V0 14 351-R 7IT..E (include...room " temperature [22 deg C3 ----------------------- 66 1.7 Differential volume under consideration ----- 71 2.1 .-.Iified four port network...natural log of both sides and differentiate , V Equation 1.41 If the acoustic pressure is harmonic then it can be written as, * L 4 U j i OEquation

Thermophysical Properties of Matter - The TPRC Data Series. Volume 4. Specific Heat - Metallic Elements and Alloys

DTIC Science & Technology

1971-01-01

alloys— sodium — sodium alloya— solder—carbon ateels—chromium steels—silicon steels—tantalum—tantalum alloys—terbium—thallium—thallium alloys—thorium...Praseodymium 45 Rhenium 46 Rhodium 47 Rubidium 48 Ruthenium 4» Samarium 50 Scandium 51 Selenium 52 Silicon 5:i Silver 54 Sodium 55 Strontium 56...Potassium ♦ Sodium 111 Sodium * Potassium 112 Tantalum ♦ Tungsten 113 Thallium + Lead, PbTl| 114 Tin ♦ Bismuth 115 Tin ♦ Indium 116 Tin+ Lead 117

The U.S. Navy in the World (2001-2010): Context for U.S. Navy Capstone Strategies and Concepts

DTIC Science & Technology

2011-12-01

Merchant Marine ocean- going shipbuilding each down to single digits US shipbuilding industry largely dependent on US Navy orders  Building few commercial...Merchant Marine ships 228 2000s: US shipbuilding industrial base 115 229 2000s: US government shipbuilding policies No US government ship construction ...Context for U.S. Navy Capstone Strategies and Concepts 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT

The Cluster Orbits With Perturbations of Keplerian Elements (COWPOKE) Equations

DTIC Science & Technology

2004-03-20

Hill’s equations2 (also known as the Clohessy - Wiltshire equations3). Hill’s equations describe the relative motion of spacecraft using a spacecraft- 2...January 2002, AAS 02-115. 2. Hill, G. W., “Researches in the Lunar Theory,” American Journal of Mathematics, Vol. 1, No. 1, 1878, pp. 5-26. 3. Clohessy ...W. H., R. S. Wiltshire , “Terminal Guidance System for Satellite Rendezvous,” Journal of the Aerospace Sciences, September 1960, pp. 653-658 4. Gim

Shock and Vibration Symposium (59th) Held in Albuquerque, New Mexico on 18-20 October 1988. Volume 2

DTIC Science & Technology

1988-10-01

030 in. Thick V-45 Rubber Shear Ply Aluminum Coated Steel Snap- FM-73 Film NAS 6703 Bolts ring 7 Polar Layers - M7885/4 Rivets 76 Required 11.5 Deg...Feedback Q. Zhang, S. Shelley 1. N. Lou and R. J. Allemang Relating Material Properties and Wave Effects in Vibration Isolators M. C. Reid, S. 0...Load-Deflection Characteristics of Rubber Element for Vibration Control Devices E. I. Rivin and B. S. Lee Vi ______ _____________ AIRBLAST Envelope

40 CFR 437.47 - Pretreatment standards for new sources (PSNS).

Code of Federal Regulations, 2013 CFR

2013-07-01

... 1.45 Silver 0.120 0.0351 Tin 0.409 0.120 Titanium 0.0947 0.0618 Vanadium 0.218 0.0662 Zinc 2.87 0... 1.45 Silver 0.120 0.0351 Tin 0.409 0.120 Titanium 0.0947 0.0618 Vanadium 0.218 0.0662 Zinc 2.87 0....000739 Nickel 3.95 1.45 Silver 0.120 0.0351 Tin 0.409 0.120 Titanium 0.0947 0.0618 Vanadium 0.218 0.0662...

Genome, Functional Gene Annotation, and Nuclear Transformation of the Heterokont Oleaginous Alga Nannochloropsis oceanica CCMP1779

DTIC Science & Technology

2012-11-15

the 28.7 Mb genome of N. oceanica CCMP1779. RNA sequencing data from nitrogen-replete and nitrogen- depleted growth conditions support a total of... sequence and its analysis, protocols for the transformation of N. oceanica CCMP1779 are provided. The availability of genomic and transcriptomic data for...biochemistry of this fascinating organism group. Here we present the assembly of the 28.7 Mb genome of N. oceanica CCMP1779. RNA sequencing data from

In Silico Genome Mismatch Scanning to Map Breast Cancer Genes in Extended Pedigrees

DTIC Science & Technology

2008-07-01

University College London Annals of Human Genetics (2008) 72,279–287 279 A. Thomas et al. Methods IBD sharing in pedigrees There is considerable literature...is sufficient to maintain interest in the region. 282 Annals of Human Genetics (2008) 72,279–287 C© 2007 The Authors Journal compilation C© 2007...for observed IBS instead of IBD, and for sporadic cases reducing the number of meioses, pedigrees with meiosis count d in the 25 to 30 range are

Mapping, Charting and Geodesy Handbook

DTIC Science & Technology

1994-07-15

Air-526 at (703) 604-3380 ext 8102 or 8118 [DSN 664, -.Of a copy of DMAI 8660.10 write DMA, Attn: AMO, Stop D-2, 4600 Sangamore Rd., Bethesda MD 20816 ...Instructions, Lists, and Handbooks from DMA, Attn: AMO, Stop D-2, 4600 Sangamore Rd., Bethesda MD 20816 or call (301) 227-2026 DSN [287] or fax (301) 227...DMA Combat Support Center Attn: CCOR, Stop D-16 6001 MacArthur Blvd. Bethesda, MD 20816 fax (301) 227-2498 DSN 287-2498 3. NOT SO ROUTINE ORDERING

International Space Station (ISS)

NASA Image and Video Library

2003-02-09

This is the STS-115 insignia. This mission continued the assembly of the International Space Station (ISS) with the installation of the truss segments P3 and P4. Following the installation of the segments utilizing both the shuttle and the station robotic arms, a series of three space walks completed the final connections and prepared for the deployment of the station's second set of solar arrays. To reflect the primary mission of the flight, the patch depicts a solar panel as the main element. As the Space Shuttle Atlantis launches towards the ISS, its trail depicts the symbol of the Astronaut Office. The star burst, representing the power of the sun, rises over the Earth and shines on the solar panel. The shuttle flight number 115 is shown at the bottom of the patch, along with the ISS assembly designation 12A (the 12th American assembly mission). The blue Earth in the background reminds us of the importance of space exploration and research to all of Earth's inhabitants.

Lineage-specific expansions of retroviral insertions within the genomes of African great apes but not humans and orangutans.

PubMed

Yohn, Chris T; Jiang, Zhaoshi; McGrath, Sean D; Hayden, Karen E; Khaitovich, Philipp; Johnson, Matthew E; Eichler, Marla Y; McPherson, John D; Zhao, Shaying; Pääbo, Svante; Eichler, Evan E

2005-04-01

Retroviral infections of the germline have the potential to episodically alter gene function and genome structure during the course of evolution. Horizontal transmissions between species have been proposed, but little evidence exists for such events in the human/great ape lineage of evolution. Based on analysis of finished BAC chimpanzee genome sequence, we characterize a retroviral element (Pan troglodytes endogenous retrovirus 1 [PTERV1]) that has become integrated in the germline of African great ape and Old World monkey species but is absent from humans and Asian ape genomes. We unambiguously map 287 retroviral integration sites and determine that approximately 95.8% of the insertions occur at non-orthologous regions between closely related species. Phylogenetic analysis of the endogenous retrovirus reveals that the gorilla and chimpanzee elements share a monophyletic origin with a subset of the Old World monkey retroviral elements, but that the average sequence divergence exceeds neutral expectation for a strictly nuclear inherited DNA molecule. Within the chimpanzee, there is a significant integration bias against genes, with only 14 of these insertions mapping within intronic regions. Six out of ten of these genes, for which there are expression data, show significant differences in transcript expression between human and chimpanzee. Our data are consistent with a retroviral infection that bombarded the genomes of chimpanzees and gorillas independently and concurrently, 3-4 million years ago. We speculate on the potential impact of such recent events on the evolution of humans and great apes.

KSC-06pd0636

NASA Image and Video Library

2006-04-14

JOHNSON SPACE CENTER, TX - STS115-S-001 (February 2003) -- This is the STS-115 insignia. This mission continues the assembly of the International Space Station with the installation of the truss segments P3 and P4. Following the installation of the segments utilizing both the shuttle and the station robotic arms, a series of four space walks will complete the final connections and prepare for the deployment of the station's second set of solar arrays. To reflect the primary mission of the flight, the patch depicts a solar panel as the main element. As the Space Shuttle Atlantis launches towards the ISS, its trail depicts the symbol of the Astronaut Office. The starburst, representing the power of the sun, rises over the Earth and shines on the solar panel. The shuttle flight number 115 is shown at the bottom of the patch, along with the ISS assembly designation 12A (the 12th American assembly mission). The blue Earth in the background reminds us of the importance of space exploration and research to all of Earth's inhabitants. The NASA insignia design for shuttle flights is reserved for use by the astronauts and for other official use as the NASA Administrator may authorize. Public availability has been approved only in the forms of illustrations by the various news media. When and if there is any change in this policy, which is not anticipated, the change will be publicly announced.

Metro Commuter Exposures to Particulate Air Pollution and PM2.5-Associated Elements in Three Canadian Cities: The Urban Transportation Exposure Study.

PubMed

Van Ryswyk, Keith; Anastasopolos, Angelos T; Evans, Greg; Sun, Liu; Sabaliauskas, Kelly; Kulka, Ryan; Wallace, Lance; Weichenthal, Scott

2017-05-16

System-representative commuter air pollution exposure data were collected for the metro systems of Toronto, Montreal, and Vancouver, Canada. Pollutants measured included PM 2.5 (PM = particulate matter), PM 10 , ultrafine particles, black carbon, and the elemental composition of PM 2.5 . Sampling over three weeks was conducted in summer and winter for each city and covered each system on a daily basis. Mixed-effect linear regression models were used to identify system features related to particulate exposures. Ambient levels of PM 2.5 and its elemental components were compared to those of the metro in each city. A microenvironmental exposure model was used to estimate the contribution of a 70 min metro commute to daily mean exposure to PM 2.5 elemental and mass concentrations. Time spent in the metro was estimated to contribute the majority of daily exposure to several metallic elements of PM 2.5 and 21.2%, 11.3% and 11.5% of daily PM 2.5 exposure in Toronto, Montreal, and Vancouver, respectively. Findings suggest that particle air pollutant levels in Canadian metros are substantially impacted by the systems themselves, are highly enriched in steel-based elements, and can contribute a large portion of PM 2.5 and its elemental components to a metro commuter's daily exposure.

Optical and X-ray observations of the two BL Lac objects OJ 287 and MS 1458+22

NASA Astrophysics Data System (ADS)

Massaro, E.; Giommi, P.; Perri, M.; Tagliaferri, G.; Nesci, R.; Tosti, G.; Ciprini, S.; Montagni, F.; Ravasio, M.; Ghisellini, G.; Frasca, A.; Marilli, E.; Valentini, G.; Kurtanidze, O. M.; Nikolashvili, M. G.

2003-02-01

We present the results of recent BeppoSAX observations of the two BL Lac objects OJ 287 and MS 1458+22 in bright optical states and of simultaneous photometric measurements in the bandpasses from I to U. OJ 287 was observed in November 2001 and MS 1458+22 in February of the same year. The X-ray flux of OJ 287 was rather low, F(2-10 keV) = (1.35+/-0.15)x 10-12 erg cm-2 s-1 and its spectrum is well described by a single power law with an energy index 0.45+/-0.08, flatter than that measured in the optical, equal to 1.53+/-0.03. The X-ray emission of MS 1458+22 was characterized by a low flux level of F(2-10 keV) = (7.5+/-0.6)x 10-13 erg cm-2 s-1, with a steeper spectral index of 1.71+/-0.15, while in the optical it was 0.99+/-0.06. We show that the broad-band SEDs of these two sources can be well represented by log-parabolic spectral laws and evaluate their parameters. This law, already observed for the synchrotron components of other BL Lac sources, can be explained if the emitting particles are accelerated by some statistical mechanism having a probability of energy gain that is a decreasing function of the energy itself.

Micronucleus frequency in copper-mine workers exposed to arsenic is modulated by the AS3MT Met287Thr polymorphism.

PubMed

Hernández, Alba; Paiva, Leiliane; Creus, Amadeu; Quinteros, Domingo; Marcos, Ricard

2014-01-01

Arsenic(III)methyltransferase (AS3MT) has been demonstrated to be the key enzyme in the metabolism of arsenic as it catalyses the methylation of arsenite and monomethylarsonic acid (MMA) to form methylated arsenic species, which have higher toxic and genotoxic potential than the parent compounds. The aim of this study is to evaluate if genetic variation in the AS3MT gene influences arsenic-induced cytogenetic damage, measured by the micronucleus (MN) assay. AS3MT Met287Thr allele frequencies and MN values were determined for 207 subjects working in the copper-mine industry, who were exposed to variable levels of arsenic. The urinary arsenic profile was used as individual biomarker of arsenic exposure. Results indicate that the MN frequencies found in peripheral blood lymphocytes of the exposed population poorly correlate with the levels of total arsenic content in urine. Nevertheless, when workers were classified according to their AS3MT Met287Thr genotypes, significantly higher MN values were observed for those carrying the variant allele [odds ratio (OR), 3.4 (1.6-5.2); P=0.0003)]. To our knowledge, these results are the first to show that genetic variation in AS3MT, especially the Met287Thr polymorphism, may play a role in modulating the levels of arsenic-induced cytogenetic damage among individuals chronically exposed to arsenic. Copyright © 2013 Elsevier B.V. All rights reserved.

Equalizer design techniques for dispersive cables with application to the SPS wideband kicker

NASA Astrophysics Data System (ADS)

Platt, Jason; Hofle, Wolfgang; Pollock, Kristin; Fox, John

2017-10-01

A wide-band vertical instability feedback control system in development at CERN requires 1-1.5 GHz of bandwidth for the entire processing chain, from the beam pickups through the feedback signal digital processing to the back-end power amplifiers and kicker structures. Dispersive effects in cables, amplifiers, pickup and kicker elements can result in distortions in the time domain signal as it proceeds through the processing system, and deviations from linear phase response reduce the allowable bandwidth for the closed-loop feedback system. We have developed an equalizer analog circuit that compensates for these dispersive effects. Here we present a design technique for the construction of an analog equalizer that incorporates the effect of parasitic circuit elements in the equalizer to increase the fidelity of the implemented equalizer. Finally, we show results from the measurement of an assembled backend equalizer that corrects for dispersive elements in the cables over a bandwidth of 10-1000 MHz.

28 CFR 115.152-115.153 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false [Reserved] 115.152-115.153 Section 115.152-115.153 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Reporting §§ 115.152-115.153 [Reserved] ...

28 CFR 115.152-115.53 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false [Reserved] 115.152-115.53 Section 115.152-115.53 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Reporting §§ 115.152-115.53 [Reserved] ...

28 CFR 115.152-115.53 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false [Reserved] 115.152-115.53 Section 115.152-115.53 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Reporting §§ 115.152-115.53 [Reserved] ...

OJ287: Deciphering the "Rosetta stone of blazars★"

NASA Astrophysics Data System (ADS)

Britzen, S.; Fendt, C.; Witzel, G.; Qian, S.-J.; Pashchenko, I. N.; Kurtanidze, O.; Zajacek, M.; Martinez, G.; Karas, V.; Aller, M.; Aller, H.; Eckart, A.; Nilsson, K.; Arévalo, P.; Cuadra, J.; Subroweit, M.; Witzel, A.

2018-04-01

OJ287 is the best candidate Active Galactic Nucleus (AGN) for hosting a supermassive binary black hole (SMBBH) at very close separation. We present 120 Very Long Baseline Array (VLBA) observations (at 15 GHz) covering the time between Apr. 1995 and Apr. 2017. We find that the OJ287 radio jet is precessing on a timescale of ˜ 22 yr. In addition, our data are consistent with a jet-axis rotation on a yearly timescale. We model the precession (24±2 yr) and combined motion of jet precession and jet-axis rotation. The jet motion explains the variability of the total radio flux-density via viewing angle changes and Doppler beaming. Half of the jet-precession timescale is of the order of the dominant optical periodicity timescale. We suggest that the optical emission is synchrotron emission and related to the jet radiation. The jet dynamics and flux-density light curves can be understood in terms of geometrical effects. Disturbances of an accretion disc caused by a plunging black hole do not seem necessary to explain the observed variability. Although the SMBBH model does not seem necessary to explain the observed variability, a SMBBH or Lense-Thirring precession (disc aSround single black hole) seem to be required to explain the timescale of the precessing motion. Besides jet rotation also nutation of the jet axis could explain the observed motion of the jet axis. We find a strikingly similar scaling for the timescales for precession and nutation as indicated for SS433 with a factor of roughly 50 times longer in OJ287.

Altered activity-rest patterns in mice with a human autosomal-dominant nocturnal frontal lobe epilepsy mutation in the β2 nicotinic receptor

PubMed Central

Xu, Jian; Cohen, Bruce N.; Zhu, Yongling; Dziewczapolski, Gustavo; Panda, Satchidananda; Lester, Henry A.; Heinemann, Stephen F.; Contractor, Anis

2010-01-01

High-affinity nicotinic receptors containing beta2 subunits (β2*) are widely expressed in the brain, modulating many neuronal processes and contributing to neuropathologies such as Alzheimer’s disease, Parkinson’s disease and epilepsy. Mutations in both the α4 and β2 subunits are associated with a rare partial epilepsy, autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE). Here we introduced one such human missense mutation into the mouse genome to generate a knock-in strain carrying a valine-to-leucine mutation β2V287L.β2V287L mice were viable and born at an expected Mendelian ratio. Surprisingly, mice did not display an overt seizure phenotype; however homozygous mice did display significant alterations in their activity-rest patterns. This was manifest as an increase in activity during the light cycle suggestive of disturbances in the normal sleep patterns of mice; a parallel phenotype to that found in human ADNFLE patients. Consistent with the role of nicotinic receptors in reward pathways, we found that β2V287L mice did not develop a normal proclivity to voluntary wheel running, a model for natural reward. Anxiety-related behaviors were also affected by the V287L mutation. Mutant mice spent more time in the open arms on the elevated plus maze (EPM) suggesting that they had reduced levels of anxiety. Together, these findings emphasize several important roles of β2* nicotinic receptors in complex biological processes including the activity-rest cycle, natural reward, and anxiety. PMID:20603624

Chains weigh on on access. The FAH joins the throng offering proposals to solve the uninsured crisis, but some say their plan lacks a key element.

PubMed

Benko, Laura B

2007-02-26

Yet another proposal for covering the uninsured landed in the news last week, as the Federation of American Hospitals offered its plan, estimated to cost 115 dollar billion annually. While the plan drew some praise, others questioned its validity. "It's hard to take seriously a proposal that doesn't even attempt to address the fundamental issue of how all is this going to get paid for," says Susan Sherry, left.

Installation Restoration Program Environmental Technology Development. Biodegradation of DIMP, Dieldrin, Isodrin, DBCP, and PCPMSO in Rocky Mountain Arsenal Soils

DTIC Science & Technology

1989-01-30

D-007 & Hazardous Materials Agency 1 CETHA-TE Task No. 11 . ADDRESS (City, State, and ZIP Code) 10. SOURCE OF FUNDING NUMBERS ATTN: CETHA-TE-D...PROGRAM IPROJECT TASK IWORK UNIT Aberdeen Proving Ground, MD 21010-5401 ELEMENT NO. NO. NO. ACCESSION NO. 1 . TITLE (Include SecurityClassification...Peter J. Marks 3a. TYPE OF REPORT 13b. TIME COVERED T14. DATE OF REPORT (Year, Month, Day) 115. PAGE COUNT Final FROM 1 /87 TO_1/89 11989 January 3 6

First experiment at TASCA towards X-ray fingerprinting of element 115 decay chains

DOE Office of Scientific and Technical Information (OSTI.GOV)

Forsberg, U.; Golubev, P.; Sarmiento, L. G.

2012-01-01

To identify the atomic number of superheavy nuclei produced in 48Ca-induced fusion-evaporation reactions, an experiment aiming at measuring characteristic X-rays is being prepared at GSI, Darmstadt, Germany. The gas-filled separator TASCA will be employed, sending the residues towards the multi-coincidence detector setup TASISpec. Two ionoptical modes relying on differing magnetic polarities of the quadrupole magnets can be used at TASCA. New simulations and experimental tests of transmission and background suppression for these two focusing modes into TASISpec are presented.

Analysis of Wake Survey Experimental Data for Model 5365 Representing the R/V ATHENA with and without the Bass Dynamometer Boat.

DTIC Science & Technology

1981-01-01

and L. BRUCE CROOK N00167-78-.089 PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT. PROJECT, TASK AREA a WORK UNIT NUMBERS DAVID TAYLOR...e, I i.eOs I .e𔄁 .Ie.255. 2 ..i1 -,1sat . i.. 1,1’i -o51 .115 757-s 2.57’ -,i1i .11’ t~, 2.357 ,it -’lie isisl 2.25 soiC .224 isq,. i.e’s *,i76

An Expert-System-Like Feedback Approach in the hp-Version of the Finite Element Method.

DTIC Science & Technology

1986-05-01

and, besides some research codes, the authors know of only two commercial programs based on the p-version. These are the computer program PROBE ( Noetic ...assumptions. Let us first study the problem of the best approximation on the interval I=(-1,1) . Let for E < 1 (x + X - for x > 0 for x and let W(a,E,x) = (x...Comp. and Maths. with Appls., 5, pp. 99-115, 1979. [𔃼] Szabo, B., PROBE: Theoretical Manual, NOETIC Technology Corporation, 7980 Clayton Road, Suite 205

Heavy metals concentrations in scalp hairs of ASGM miners and inhabitants of the Gorontalo Utara regency

NASA Astrophysics Data System (ADS)

Indriati Arifin, Yayu; Sakakibara, Masayuki; Sera, Koichiro

2017-06-01

We performed the Particle Induced X-ray Emission (PIXE) analysis on scalp hair samples of 115 ASGM miners and inhabitants of Gorontalo Utara regency. Along with mercury (Hg), we presented other trace elements such as Copper (Cu) and Manganese (Mn). Concentrations of Cu, Mn and Hg in the scalp hairs of ASGM miners are higher non miners. Significant and positive correlations coefficients between Cu and Hg concentration with Mn concentration may indicate that there are still unknown metabolism process related with ASGM activities.

Optical Coherence Tomography Updates on Clinical and Technical Developments. Age-Related Macular Degeneration: Drusen and Geographic Atrophy

NASA Astrophysics Data System (ADS)

Fleckenstein, Monika; Schmitz-Valckenberg, Steffen; Holz, Frank G.

Age-related macular degeneration (AMD) is a complex disease with both genetic and environmental factors influencing its development. With the advent of high-resolution OCT imaging, the characterization of drusen in AMD has become possible. The in vivo morphologic characteristics imaged with SD-OCT may represent distinct subclasses of drusen variants, may relate closely to ultrastructural drusen elements identified in donor eyes, and may be useful imaging biomarkers for disease severity or risk of progression [Khanifar et al. Ophthalmology 115(11):1883-1890, 2008].

The effect of parity on maternal body mass index, plasma mineral element status and new-born anthropometrics.

PubMed

Ugwuja, Emmanuel I; Nnabu, Richard C; Ezeonu, Paul O; Uro-Chukwu, Henry

2015-09-01

Adverse pregnancy outcome is an important public health problem that has been partly associated with increasing maternal parity. To determine the effect of parity on maternal body mass index (BMI), mineral element status and newborn anthropometrics. Data for 349 pregnant women previously studied for the impacts of maternal plasma mineral element status on pregnancy and its outcomes was analysed. Obstetric and demographic data and 5mls of blood samples were obtained from each subject. Blood lead, plasma copper, iron and zinc were determined using atomic absorption spectrophotometer. Maternal BMI increases with parity. Women with parity two had significantly higher plasma zinc but lower plasma copper with comparable levels of the elements in nulliparous and higher parity groups. Although plasma iron was comparable among the groups, blood lead was significantly higher in parity > three. Newborn birth length increases with parity with a positive correlation between parity and maternal BMI (r = 0.221; p = 0.001) and newborn birth length (r = 0.170; p = 0.002) while plasma copper was negatively correlated with newborn's head circumference (r = -0.115; p = 0.040). It is plausible that parity affects maternal BMI and newborn anthropometrics through alterations in maternal plasma mineral element levels. While further studies are desired to confirm the present findings, there is need for pregnant and would-be pregnant women to diversify their diet to optimize their mineral element status.

210Polonium bioaccessibility assessment in algae for human consumption: An in vitro gastrointestinal digestion method.

PubMed

Desideri, Donatella; Meli, Maria Assunta; Roselli, Carla; Feduzi, Laura; Ugolini, Lucia

2017-01-01

The occurrence and mobility of natural radioactive element as 210 Polonium ( 210 Po) in 13 commercial algae consumed in Italy by humans were determined because the effects on human health need to take into account the bioavailability of these elements. The simulation of gastrointestinal (GIT) digestion was divided into three stages and was accomplished using three different artificial solutions: saliva, gastric, and synthetic bile-pancreas solution. The same sample was treated in two different ways: a) only gastric digestion and b) complete GIT digestion (gastric digestion followed by bile-pancreas solution). The difference between Po gastric mobility with respect to that found for GIT digestion was not significant; in fact, Po mobility exhibited a mean value 17.2 ± 15.1% and 19.5 ± 11.5% for gastric and GIT digestion, respectively.

Multiband optical variability of the blazar OJ 287 during its outbursts in 2015-2016

NASA Astrophysics Data System (ADS)

Gupta, Alok C.; Agarwal, Aditi; Mishra, Alka; Gaur, H.; Wiita, P. J.; Gu, M. F.; Kurtanidze, O. M.; Damljanovic, G.; Uemura, M.; Semkov, E.; Strigachev, A.; Bachev, R.; Vince, O.; Zhang, Z.; Villarroel, B.; Kushwaha, P.; Pandey, A.; Abe, T.; Chanishvili, R.; Chigladze, R. A.; Fan, J. H.; Hirochi, J.; Itoh, R.; Kanda, Y.; Kawabata, M.; Kimeridze, G. N.; Kurtanidze, S. O.; Latev, G.; Dimitrova, R. V. Muñoz; Nakaoka, T.; Nikolashvili, M. G.; Shiki, K.; Sigua, L. A.; Spassov, B.

2017-03-01

We present recent optical photometric observations of the blazar OJ 287 taken during 2015 September-2016 May. Our intense observations of the blazar started in 2015 November and continued until 2016 May and included detection of the large optical outburst in 2015 December that was predicted using the binary black hole model for OJ 287. For our observing campaign, we used a total of nine ground-based optical telescopes of which one is in Japan, one is in India, three are in Bulgaria, one is in Serbia, one is in Georgia, and two are in the USA. These observations were carried out in 102 nights with a total of ∼1000 image frames in BVRI bands, though the majority were in the R band. We detected a second comparably strong flare in 2016 March. In addition, we investigated multiband flux variations, colour variations, and spectral changes in the blazar on diverse time-scales as they are useful in understanding the emission mechanisms. We briefly discuss the possible physical mechanisms most likely responsible for the observed flux, colour, and spectral variability.

Telomere-related lung fibrosis is diagnostically heterogeneous but uniformly progressive

PubMed Central

Newton, Chad A.; Batra, Kiran; Torrealba, Jose; Kozlitina, Julia; Glazer, Craig S.; Aravena, Carlos; Meyer, Keith; Raghu, Ganesh; Collard, Harold R.; Garcia, Christine Kim

2017-01-01

Heterozygous mutations in four telomere-related genes have been linked to pulmonary fibrosis, but little is known about similarities or differences of affected individuals. 115 patients with mutations in telomerase reverse transcriptase (TERT) (n=75), telomerase RNA component (TERC) (n=7), regulator of telomere elongation helicase 1 (RTEL1) (n=14) and poly(A)-specific ribonuclease (PARN) (n=19) were identified and clinical data were analysed. Approximately one-half (46%) had a multidisciplinary diagnosis of idiopathic pulmonary fibrosis (IPF); others had unclassifiable lung fibrosis (20%), chronic hypersensitivity pneumonitis (12%), pleuroparenchymal fibroelastosis (10%), interstitial pneumonia with autoimmune features (7%), an idiopathic interstitial pneumonia (4%) and connective tissue disease-related interstitial fibrosis (3%). Discordant interstitial lung disease diagnoses were found in affected individuals from 80% of families. Patients with TERC mutations were diagnosed at an earlier age than those with PARN mutations (51±11 years versus 64±8 years; p=0.03) and had a higher incidence of haematological comorbidities. The mean rate of forced vital capacity decline was 300 mL·year−1 and the median time to death or transplant was 2.87 years. There was no significant difference in time to death or transplant for patients across gene mutation groups or for patients with a diagnosis of IPF versus a non-IPF diagnosis. Genetic mutations in telomere related genes lead to a variety of interstitial lung disease (ILD) diagnoses that are universally progressive. PMID:27540018

Telomere-related lung fibrosis is diagnostically heterogeneous but uniformly progressive.

PubMed

Newton, Chad A; Batra, Kiran; Torrealba, Jose; Kozlitina, Julia; Glazer, Craig S; Aravena, Carlos; Meyer, Keith; Raghu, Ganesh; Collard, Harold R; Garcia, Christine Kim

2016-12-01

Heterozygous mutations in four telomere-related genes have been linked to pulmonary fibrosis, but little is known about similarities or differences of affected individuals.115 patients with mutations in telomerase reverse transcriptase (TERT) (n=75), telomerase RNA component (TERC) (n=7), regulator of telomere elongation helicase 1 (RTEL1) (n=14) and poly(A)-specific ribonuclease (PARN) (n=19) were identified and clinical data were analysed.Approximately one-half (46%) had a multidisciplinary diagnosis of idiopathic pulmonary fibrosis (IPF); others had unclassifiable lung fibrosis (20%), chronic hypersensitivity pneumonitis (12%), pleuroparenchymal fibroelastosis (10%), interstitial pneumonia with autoimmune features (7%), an idiopathic interstitial pneumonia (4%) and connective tissue disease-related interstitial fibrosis (3%). Discordant interstitial lung disease diagnoses were found in affected individuals from 80% of families. Patients with TERC mutations were diagnosed at an earlier age than those with PARN mutations (51±11 years versus 64±8 years; p=0.03) and had a higher incidence of haematological comorbidities. The mean rate of forced vital capacity decline was 300 mL·year -1 and the median time to death or transplant was 2.87 years. There was no significant difference in time to death or transplant for patients across gene mutation groups or for patients with a diagnosis of IPF versus a non-IPF diagnosis.Genetic mutations in telomere related genes lead to a variety of interstitial lung disease (ILD) diagnoses that are universally progressive. Copyright ©ERS 2016.

A comparison between audio computer-assisted self-interviews and clinician interviews for obtaining the sexual history.

PubMed

Kurth, Ann E; Martin, Diane P; Golden, Matthew R; Weiss, Noel S; Heagerty, Patrick J; Spielberg, Freya; Handsfield, H Hunter; Holmes, King K

2004-12-01

The objective of this study was to compare reporting between audio computer-assisted self-interview (ACASI) and clinician-administered sexual histories. The goal of this study was to explore the usefulness of ACASI in sexually transmitted disease (STD) clinics. The authors conducted a cross-sectional study of ACASI followed by a clinician history (CH) among 609 patients (52% male, 59% white) in an urban, public STD clinic. We assessed completeness of data, item prevalence, and report concordance for sexual history and patient characteristic variables classified as socially neutral (n=5), sensitive (n=11), or rewarded (n=4). Women more often reported by ACASI than during CH same-sex behavior (19.6% vs. 11.5%), oral sex (67.3% vs. 50.0%), transactional sex (20.7% vs. 9.8%), and amphetamine use (4.9% vs. 0.7%) but were less likely to report STD symptoms (55.4% vs. 63.7%; all McNemar chi-squared P values <0.003). Men's reporting was similar between interviews, except for ever having had sex with another man (36.9% ACASI vs. 28.7% CH, P <0.001). Reporting agreement as measured by kappas and intraclass correlation coefficients was only moderate for socially sensitive and rewarded variables but was substantial or almost perfect for socially neutral variables. ACASI data tended to be more complete. ACASI was acceptable to 89% of participants. ACASI sexual histories may help to identify persons at risk for STDs.

Anatomically Realistic Three-Dimensional Meshes of the Pelvic Floor & Anal Canal for Finite Element Analysis

PubMed Central

Noakes, Kimberley F.; Bissett, Ian P.; Pullan, Andrew J.; Cheng, Leo K.

2014-01-01

Three anatomically realistic meshes, suitable for finite element analysis, of the pelvic floor and anal canal regions have been developed to provide a framework with which to examine the mechanics, via finite element analysis of normal function within the pelvic floor. Two cadaver-based meshes were produced using the Visible Human Project (male and female) cryosection data sets, and a third mesh was produced based on MR image data from a live subject. The Visible Man (VM) mesh included 10 different pelvic structures while the Visible Woman and MRI meshes contained 14 and 13 structures respectively. Each image set was digitized and then finite element meshes were created using an iterative fitting procedure with smoothing constraints calculated from ‘L’-curves. These weights produced accurate geometric meshes of each pelvic structure with average Root Mean Square (RMS) fitting errors of less than 1.15 mm. The Visible Human cadaveric data provided high resolution images, however, the cadaveric meshes lacked the normal dynamic form of living tissue and suffered from artifacts related to postmortem changes. The lower resolution MRI mesh was able to accurately portray structure of the living subject and paves the way for dynamic, functional modeling. PMID:18317929

The decline of soil due to the pile of highway project Medan-Kualanamu (STA 35 + 901) with the finite element method

NASA Astrophysics Data System (ADS)

Hastuty, I. P.; Roesyanto; Sihite, A. B.

2018-02-01

Consolidation is the process of discharge of water from the ground through the pore cavity. Consolidation occurs in soft soil or unstable soil that allows an improvement in order to make the soil more stable. The method of using Prefabricated Vertical Drain (PVD) is one way to improve unstable soils. PVD works like a sand column that can drain water vertically. This study aims to determine the decrease, pore water pressure and soil consolidation rate with Prefabricated Vertical Drain (PVD) and without PVD analytically and using finite element method that affect the duration of soil decline to reach 90% consolidation or in other words soil does not decline anymore. Based on the analytical calculation, the decrease obtained is equal to 0.47 m meanwhile the result of calculation using finite element method is 0.45 m. The consolidation rate obtained from analytical calculation is 19 days with PVD and 115 days without PVD. The consolidation rate obtained from finite element method is 63 days with PVD and 110 days without PVD. And the pore water pressure is 0.92 KN/m2.

Involvement of Hu and heterogeneous nuclear ribonucleoprotein K in neuronal differentiation through p21 mRNA post-transcriptional regulation.

PubMed

Yano, Masato; Okano, Hirotaka J; Okano, Hideyuki

2005-04-01

The Hu family is a group of neuronal RNA-binding proteins required for neuronal differentiation in the developing nervous system. Previously, Hu proteins have been shown to enhance the stabilization and/or translation of target mRNAs, such as p21 (CIP1), by binding to AU-rich elements in untranslated regions (UTRs). In this study, we show that Hu induces p21 expression, cell cycle arrest, and neuronal differentiation in mouse neuroblastoma N1E-115 cells. p21 expression is also up-regulated during Me2SO-induced differentiation in N1E-115 cells and is controlled by post-transcriptional mechanisms through its 3'-UTR. To investigate the molecular mechanisms of Hu functions, we used a proteomics strategy to isolate Hu-interacting proteins and identified heterogeneous nuclear ribonucleoprotein (hnRNP) K. hnRNP K also specifically binds to CU-rich sequences in p21 mRNA 3'-UTR and represses its translation in both nonneuronal and neuronal cells. Further, using RNA interference experiments, we show that the Hu-p21 pathway contributes to the regulation of neurite outgrowth and proliferation in N1E-115 cells, and this pathway is antagonized by hnRNP K. Our results suggest a model in which the mutually antagonistic action of two RNA-binding proteins, Hu and hnRNP K, control the timing of the switch from proliferation to neuronal differentiation through the post-transcriptional regulation of p21 mRNA.

Family physicians' ability to perform population management is associated with adoption of other aspects of the patient-centered medical home.

PubMed

Ottmar, Jessica; Blackburn, Brenna; Phillips, Robert L; Peterson, Lars E; Jaén, Carlos Roberto

2015-04-01

The patient-centered medical home (PCMH) model is considered a promising approach to improving population health, but how elements of these advanced practice models relate to population health capability is unknown. To measure associations between family physicians' performance of population management with PCMH components, a cross-sectional survey was conducted with physicians accessing the American Board of Family Medicine Web site in 2011. Bivariate analysis and logistic regression tested associations between physician and practice demographics and specific PCMH features. The primary outcome was performance of population management. The final sample included 3855 physicians, 37.3% of whom reported performing population management. Demographic characteristics significantly associated with greater use of population management were female sex and graduation from an international medical school. PCMH components that remained associated with population management after adjustment were access to clinical case managers (odds ratio [OR]=2.01, 95% confidence interval [95% CI]: 1.69, 2.39), behavioral health collaboration (OR=1.49, 95% CI: 1.26, 1.77), having an electronic health record that supports meaningful use (OR=1.47, 95% CI: 1.25, 1.74), recent participation in a quality improvement project (OR=2.47, 95% CI: 2.12, 2.89), and routine measurement of patient difficulty securing an appointment (OR=2.87, 95% CI: 2.45, 3.37). Performance of population management was associated with several PCMH elements and resources not present in traditional primary care offices. Attention to these elements likely will enhance delivery of population management services in primary care.

Prayer Attendance and General Health in the Iranian Adult Urban Population.

PubMed

Sotodehasl, Nemat; Ghorbani, Raheb; Mahdavi-Nejad, Gholamhosein; Haji-Aghajani, Saeed; Mehdizadeh, Jamileh

2016-02-01

This study was conducted to determine the relationship between prayer attendance and general health among adult urban population in Iran. A total of 470 males older than 17 years, chosen by multistage sampling, were investigated. The results showed that people who did not perform prayers compared to those who said prayers on time and performed Nafilahs (supererogatory prayers) were 2.87 (OR 2.87, 95 % CI 1.23-6.70, p = 0.015) times at risk of general health problems. In conclusion, the findings show that increasing the degree of people's belief in prayer can lead to improve general health.

August 2006 Status of Forces Survey of Active Duty Members: Administration, Datasets, and Codebook

DTIC Science & Technology

2006-12-01

beverages on any one occasion? Yes No f. Posters g. Web sites h. Brochures i. Other ATTITUDES...retired" f. Posters NOT [SRSVC1] = "None, I have separated or retired" g. Web sites NOT [SRSVC1] = "None...AL115E* 115e. [115e] Drinking info: news 419 AL115ER Recode AL115ER:common denom 159 AL115F* 115f. [115f] Drinking info: posters 420 AL115FR Recode

The predicted secondary structures of class I fructose-bisphosphate aldolases.

PubMed Central

Sawyer, L; Fothergill-Gilmore, L A; Freemont, P S

1988-01-01

The results of several secondary-structure prediction programs were combined to produce an estimate of the regions of alpha-helix, beta-sheet and reverse turns for fructose-bisphosphate aldolases from human and rat muscle and liver, from Trypanosoma brucei and from Drosophila melanogaster. All the aldolase sequences gave essentially the same pattern of secondary-structure predictions despite having sequences up to 50% different. One exception to this pattern was an additional strongly predicted helix in the rat liver and Drosophila enzymes. Regions of relatively high sequence variation generally were predicted as reverse turns, and probably occur as surface loops. Most of the positions corresponding to exon boundaries are located between regions predicted to have secondary-structural elements consistent with a compact structure. The predominantly alternating alpha/beta structure predicted is consistent with the alpha/beta-barrel structure indicated by preliminary high-resolution X-ray diffraction studies on rabbit muscle aldolase [Sygusch, Beaudry & Allaire (1986) Biophys. J. 49, 287a]. Images Fig. 1. (cont.) Fig. 1. PMID:3128269

Cardiac cine imaging at 3 Tesla: initial experience with a 32-element body-array coil.

PubMed

Fenchel, Michael; Deshpande, Vibhas S; Nael, Kambiz; Finn, J Paul; Miller, Stephan; Ruehm, Stefan; Laub, Gerhard

2006-08-01

We sought to assess the feasibility of cardiac cine imaging and evaluate image quality at 3 T using a body-array coil with 32 coil elements. Eight healthy volunteers (3 men; median age 29 years) were examined on a 3-T magnetic resonance scanner (Magnetom Trio, Siemens Medical Solutions) using a 32-element phased-array coil (prototype from In vivo Corp.). Gradient-recalled-echo (GRE) cine (GRAPPAx3), GRE cine with tagging lines, steady-state-free-precession (SSFP) cine (GRAPPAx3 and x4), and SSFP cine(TSENSEx4 andx6) images were acquired in short-axis and 4-chamber view. Reference images with identical scan parameters were acquired using the total-imaging-matrix (Tim) coil system with a total of 12 coil elements. Images were assessed by 2 observers in a consensus reading with regard to image quality, noise and presence of artifacts. Furthermore, signal-to-noise values were determined in phantom measurements. In phantom measurements signal-to-noise values were increased by 115-155% for the various cine sequences using the 32-element coil. Scoring of image quality yielded statistically significant increased image quality with the SSFP-GRAPPAx4, SSFP-TSENSEx4, and SSFP-TSENSEx6 sequence using the 32-element coil (P < 0.05). Similarly, scoring of image noise yielded a statistically significant lower noise rating with the SSFP-GRAPPAx4, GRE-GRAPPAx3, SSFP-TSENSEx4, and SSFP-TSENSEx6 sequence using the 32-element coil (P < 0.05). This study shows that cardiac cine imaging at 3 T using a 32-element body-array coil is feasible in healthy volunteers. Using a large number of coil elements with a favorable sensitivity profile supports faster image acquisition, with high diagnostic image quality even for high parallel imaging factors.

Environmental exposure to arsenic, AS3MT polymorphism and prevalence of diabetes in Mexico

PubMed Central

Drobná, Zuzana; Del Razo, Luz M.; García-Vargas, Gonzalo G.; Sánchez-Peña, Luz C.; Barrera-Hernández, Angel; Stýblo, Miroslav; Loomis, Dana

2014-01-01

Exposure to arsenic in drinking water is associated with increased prevalence of diabetes. We previously reported an association of diabetes and urinary concentration of dimethylarsinite (DMAsIII), a toxic product of arsenic methylation by arsenic ( +3 oxidation state) methyltransferase (AS3MT). Here we examine associations between AS3MT polymorphism, arsenic metabolism and diabetes. Fasting blood glucose, oral glucose tolerance and self-reported diagnoses were used to identify diabetic individuals. Inorganic arsenic and its metabolites were measured in urine. Genotyping analysis focused on six polymorphic sites of AS3MT. Individuals with M287T and G4965C polymorphisms had higher levels of urinary DMAsIII and were more frequently diabetic than the respective wild-type carriers, although the excess was not statistically significant. Odds ratios were 11.4 (95% confidence interval (CI) 2.2–58.8) and 8.8 (95% CI 1.6–47.3) for the combined effects of arsenic exposure >75th percentile and 287T and 4965C genotypes, respectively. Carriers of 287T and 4965C may produce more DMAsIII and be more likely to develop diabetes when exposed to arsenic. PMID:23093101

An Interesting Cause of Mechanical Small Bowel Obstruction.

PubMed

Anantha Sathyanarayana, Sandeep; Deutsch, Gary B; Friedman, Barak

2015-12-01

Foreign body ingestion is a known cause of abdominal pain in pediatric population occurring between 6 months and 3 years of age (Wyllie Curr Opin Pediatr 18:563, 2006, Uyemura Am Fam Physician 72:287, 2005, Banerjee Indian J Pediatr 72:173, 2005). Most of the ingested foreign bodies pass spontaneously with 10-20 % requiring endoscopic retrieval, and <1 % of cases require a surgical intervention (Wyllie Curr Opin Pediatr 18:563, 2006, Uyemura Am Fam Physician 72:287, 2005, Shivakumar Indian J Pediatr 71:689, 2004). Presence of intestinal obstruction necessitates surgical intervention to extract the ingested foreign body. Initial abdominal plain radiograph should be obtained when foreign body ingestion is suspected, which differentiates a radiopaque from radiolucent foreign bodies. A computed tomography with 3D reconstruction (3D-CT) is recommended with radiolucent foreign bodies (Uyemura Am Fam Physician 72:287, 2005, Kazam Am J Emerg Med 23:897, 2005). After 24 h of expectant management, failure of spontaneous passage requires further intervention. Timely intervention to relieve the obstruction is pivotal to prevent undue complications. We present an interesting case of a boy who ingested a radiolucent foreign body diagnosed on 3D-CT, successfully treated with surgical extraction.

Bloodletting therapy in hemochromatosis: Does it affect trace element homeostasis?

PubMed

Bolann, Bjørn J; Distante, Sonia; Mørkrid, Lars; Ulvik, Rune J

2015-01-01

Hemochromatosis is the most common hereditary disorder in the Nordic population, if left untreated it can result in severe parenchymal iron accumulation. Bloodletting is mainstay treatment. Iron and trace elements partially share cellular uptake and transport mechanisms, and the aim of the present study was to see if bloodletting for hemochromatosis affects trace elements homeostasis. We recruited patients referred for diagnosis and treatment of hemochromatosis, four women and 22 men 23-68 years of age. Thirteen were C282Y homozygote, one was C282Y heterozygote, three were H63D homozygote, seven were compound heterozygote and two had none of the mutations above. Iron and liver function tests were performed; serum levels of trace elements were measured using inductively coupled plasma mass spectrometry. Results before the start of treatment and after normalization of iron parameters were compared. On completion of the bloodlettings the following average serum concentrations increased: Co from 5.6 to 11.5 nmol/L, serum Cu 16.2-17.6 μmol/L, Ni increased from 50.0 to 52.6 nmol/L and Sb from 13.2 to 16.3 nmol/L. Average serum Mn concentration declined from 30.2 to 28.3 nmol/L. All changes were statistically significant (by paired t-test). B, Ba, Cs, Mo, Se, Sr and Zn were not significantly changed. We conclude that bloodlettings in hemochromatosis lead to changes in trace element metabolism, including increased absorption of potentially toxic elements. Copyright © 2014 Elsevier GmbH. All rights reserved.

Trace elements and nutrients adsorption onto nano-maghemite in a contaminated-soil solution: A geochemical/statistical approach.

PubMed

Martínez-Fernández, Domingo; Bingöl, Deniz; Komárek, Michael

2014-07-15

Two experiments were carried out to study the competition for adsorption between trace elements (TEs) and nutrients following the application of nano-maghemite (NM) (iron nano-oxide; Fe2O3) to a soil solution (the 0.01molL(-1) CaCl2 extract of a TEs-contaminated soil). In the first, the nutrients K, N, and P were added to create a set of combinations: potential availability of TEs during their interaction with NM and nutrients were studied. In the second, response surface methodology was used to develop predictive models by central composite design (CCD) for competition between TEs and the nutrients K and N for adsorption onto NM. The addition of NM to the soil solution reduced specifically the concentrations of available As and Cd, but the TE-adsorption capacity of NM decreased as the P concentration increased. The CCD provided more concise and valuable information, appropriate to estimate the behavior of NM sequestering TEs: according to the suggested models, K(+) and NH4(+) were important factors for Ca, Fe, Mg, Mn, Na, and Zn adsorption (Radj(2)=95%, except for Zn with Radj(2)=87%). The obtained information and models can be used to predict the effectiveness of NM for the stabilization of TEs, crucial during the phytoremediation of contaminated soils. Copyright © 2014 Elsevier B.V. All rights reserved.

Understanding data requirements of retrospective studies.

PubMed

Shenvi, Edna C; Meeker, Daniella; Boxwala, Aziz A

2015-01-01

Usage of data from electronic health records (EHRs) in clinical research is increasing, but there is little empirical knowledge of the data needed to support multiple types of research these sources support. This study seeks to characterize the types and patterns of data usage from EHRs for clinical research. We analyzed the data requirements of over 100 retrospective studies by mapping the selection criteria and study variables to data elements of two standard data dictionaries, one from the healthcare domain and the other from the clinical research domain. We also contacted study authors to validate our results. The majority of variables mapped to one or to both of the two dictionaries. Studies used an average of 4.46 (range 1-12) data element types in the selection criteria and 6.44 (range 1-15) in the study variables. The most frequently used items (e.g., procedure, condition, medication) are often available in coded form in EHRs. Study criteria were frequently complex, with 49 of 104 studies involving relationships between data elements and 22 of the studies using aggregate operations for data variables. Author responses supported these findings. The high proportion of mapped data elements demonstrates the significant potential for clinical data warehousing to facilitate clinical research. Unmapped data elements illustrate the difficulty in developing a complete data dictionary. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

GBT Observations of the Star-Forming Regions DR21 and MonR2 with the new Argus Instrument

NASA Astrophysics Data System (ADS)

Linville, Dylan; Frayer, David; Cunningham, Nichol; Maddalena, Ronald

2018-01-01

We present GBT molecular line observations of DR21 and MonR2 with the new 16 element 75--115 GHz Argus instrument. Both molecular cloud complexes are associated with regions of high-mass star formation. We present the results of our 13CO, C18O, and HCO+ observations. Both MonR2 and DR21 show multiple velocity components, and the data suggest that the core of MonR2 is collapsing, while DR21 contains a region with a strong outflow traced by HCO+.

A study of uniformity of elements deposition on glass fiber filters after collection of airborne particulate matter (PM-10), using a high-volume sampler.

PubMed

Marrero, Julieta; Rebagliati, Raúl Jiménez; Gómez, Darío; Smichowski, Patricia

2005-12-15

A study was conducted to evaluate the homogeneity of the distribution of metals and metalloids deposited on glass fiber filters collected using a high-volume sampler equipped with a PM-10 sampling head. The airborne particulate matter (APM)-loaded glass fiber filters (with an active surface of about 500cm(2)) were weighed and then each filter was cut in five small discs of 6.5cm of diameter. Each disk was mineralized by acid-assisted microwave (MW) digestion using a mixture of nitric, perchloric and hydrofluoric acids. Analysis was performed by axial view inductively coupled plasma optical emission spectrometry (ICP OES) and the elements considered were: Al, As, Cd, Cr, Cu, Fe, Mn, Ni, Pb, Sb, Ti and V. The validation of the procedure was performed by the analysis of the standard reference material NIST 1648, urban particulate matter. As a way of comparing the possible variability in trace elements distribution in a particular filter, the mean concentration for each element over the five positions (discs) was calculated and each element concentration was normalized to this mean value. Scatter plots of the normalized concentrations were examined for all elements and all sub-samples. We considered that an element was homogeneously distributed if its normalized concentrations in the 45 sub-samples were within +/-15% of the mean value ranging between 0.85 and 1.15. The study demonstrated that the 12 elements tested showed different distribution pattern. Aluminium, Cu and V showed the most homogeneous pattern while Cd and Ni exhibited the largest departures from the mean value in 13 out of the 45 discs analyzed. No preferential deposition was noticed in any sub-sample.

46 CFR 160.115-5 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-10-01

... for §§ 160.115-7, 160.115-13, and 160.115-15. (4) MSC/Circular 980, Standardized Life-saving Appliance Evaluation and Test Report Forms, (February 13, 2001), IBR approved for § 160.115-13 (“IMO MSC Circ. 980...

8 CFR 287.4 - Subpoena.

Code of Federal Regulations, 2010 CFR

2010-01-01

...; Supervisory Criminal Investigators, Anti-Smuggling; Regional Directors; Service Center Directors; Assistant..., Investigations; Supervisory Criminal Investigator, Anti-Smuggling; Regional Director; Special Agent in Charge...

Performance Monitoring System: Summary of Lock Statistics for October-December 1986.

DTIC Science & Technology

1987-05-01

0 *PREVIOUS QTR 10 /85 THRU 12/85 ’ * ’ UPBOUN 255 28 35’ 96 23’ 277 52 19’ 6 * DOIWNBOUND 492 40 14’ 73 36’ 283 59 21’ 10 * O TOTAL 747 36...21’ 169 29’ 560 55 20’ 16 * ’CURRENT QTR 10 /86 THRU 12/86 ’ ’ ’ . O UPiOUND 309 54 19’ 61 37’ 287 55 33 * 7 ’ O DONiBOUND 300 47 21 64 46 ’ 287 50 34...0 *PREVIOUS QTR 10 /85 TNRU 12/85 70 .0 .0 4.0 2.4 .0 *CURRENT QTR 10 /86 THRU 12/86 47 .0 .0

Evaluating the Superpave Option in Unified Facilities Guide Specification 32-12-15.13, Hot Mix Asphalt Airfield Paving

DTIC Science & Technology

2014-06-01

M249 5.47 2.291 2.381 3.8 12.8 70.6 5,132 18 M250 5.47 2.283 2.381 4.1 13.2 68.7 5,678 19 M251 5.47 2.287 2.381 4.0 13.0 69.4 5,534 16 M252 5.47...71 143.0 M250 5.47 1179.60 664.10 1180.7 0 516.60 2.28 2.38 4.12 13.15 68.70 142.48 M251 5.47 1158.4 652.3 1158.9 506.6 2.287 2.381 4.0 13.0 69

A case-control study on the risk factors of urinary calculus in Uyghur children in the Kashi region.

PubMed

Wang, H C; Liu, C; He, H Y; Wang, M X

2015-06-01

The incidence of urinary calculus (UC) is very high in Uyghur children in the Kashi region of Xinjiang, China, which seriously affects the growth and life quality of these children. This study was aimed at investigating the risk factors of UC in Uyghur children in Kashi region. One hundred fifteen Uyghur children (age <7 years) with UC who were treated in First People's Hospital in Kashi were enrolled in the case group. A 1:1 case-control study with a questionnaire was performed. The results showed that, among the 115 UC patients, there were more boys (71.3%) than girls (28.7%), and most cases had an onset age of 1-3 years (75.7%). A lower than primary school education in the mother, drinking unboiled water, water intake <500 mL/day, and eating too much sweets were risk factors [odds ratio (OR) = 2.385, 9.160, 3.263, and 8.945, respectively], whereas vegetable intake and exposure to summer sunshine of <2 h/day were protective factors against UC onset (OR = 0.154 and 0.344, respectively). Analysis of UC-related factors in 99 cases of <3-year-old children revealed that breastfeeding was also a protective factor (OR = 0.007), whereas frequent cow's milk intake within 5 months (OR = 2.414) and frequent "panada" intake (OR = 2.529) were risk factors. The occurrence of UC in Uyghur children in the Kashi region is mainly affected by maternal educational background, quality of drinking water, water intake volume, and dietary pattern. Furthermore, geography may also have a role.

Use of artificial sweeteners and fat-modified foods in weight loss maintainers and always normal weight individuals

PubMed Central

Phelan, Suzanne; Lang, Wei; Jordan, Dustin; Wing, Rena R.

2009-01-01

Objective The purpose of this study was to compare the dietary strategies and use of fat and sugar-modified foods and beverages in a weight loss maintainer group (WLM) and an always normal weight group (NW). Subjects WLM (N = 172) had maintained ≥ 10% weight loss for 11.5 yr, and had a BMI of 22.0 kg/m2. NW (N=131) had a BMI of 21.3 kg/m2 and no history of overweight. Three, 24-h recalls on random, non-consecutive days were used to assess dietary intake. Results WLM reported consuming a diet that was lower in fat (28.7% vs. 32.6%, p < .0001) and used more fat-modification strategies than NW. WLM also consumed a significantly greater percentage of modified dairy (60% vs. 49%; p = .002) and modified dressings and sauces (55% vs. 44%; p = .006) than NW. WLM reported consuming three times more daily servings of artificially sweetened soft drinks (0.91 vs. 0.37; p = .003), significantly fewer daily servings of sugar-sweetened soft drinks (0.07 vs. 0.16; p =.03), and more daily servings of water (4.72 vs 3.48; p=.002) than NW. Conclusions These findings suggests that WLM use more dietary strategies to accomplish their weight loss maintenance, including greater restriction of fat intake, use of fat- and sugar-modified foods, reduced consumption of sugar-sweetened beverages, and increased consumption of artificially sweetened beverages. Ways to promote the use of fat-modified foods and artificial sweeteners merits further research in both prevention and treatment controlled trials. PMID:19636318

Earlier tachycardia onset in right than left mesial temporal lobe seizures.

PubMed

Kato, Kazuhiro; Jin, Kazutaka; Itabashi, Hisashi; Iwasaki, Masaki; Kakisaka, Yosuke; Aoki, Masashi; Nakasato, Nobukazu

2014-10-07

To clarify whether the presence and timing of peri-ictal heart rate (HR) change is a seizure lateralizing sign in patients with mesial temporal lobe epilepsy (mTLE). Long-term video EEGs were retrospectively reviewed in 21 patients, 7 men and 14 women aged 13 to 67 years, diagnosed as mTLE with MRI lesions in the mesial temporal structures (hippocampal sclerosis in 20 cases, amygdala hypertrophy in 1 case). Seventy-seven partial seizures without secondary generalization were extracted. Peri-ictal HR change was compared between 29 right seizures (9 patients) and 48 left seizures (12 patients). HR abruptly increased in all 29 right seizures and 42 of 48 left seizures. Onset time of HR increase in relation to ictal EEG onset was significantly earlier in right seizures than in left seizures (mean ± SD, -11.5 ± 14.8 vs 9.2 ± 21.7 seconds; p < 0.0001). Time of maximum HR was also significantly earlier in right seizures than in left seizures (36.0 ± 18.1 vs 58.0 ± 28.7 seconds; p < 0.0001). Maximum HR changes from baseline showed no significant difference between right and left seizures (47.5 ± 19.1 vs 40.8 ± 20.0/min). Significantly earlier tachycardia in right than left mTLE seizures supports previous hypotheses that the right cerebral hemisphere is dominant in the sympathetic network. No HR change, or delayed tachycardia possibly due to seizure propagation to the right hemisphere, may be a useful lateralizing sign of left mTLE seizures. © 2014 American Academy of Neurology.

Cytoskeleton changes following differentiation of N1E-115 neuroblastoma cell line.

PubMed

Oh, J-E; Karlmark Raja, K; Shin, J-H; Pollak, A; Hengstschläger, M; Lubec, G

2006-10-01

No systematic approach to detect expression of differentiation-related elements was published so far. The undifferentiated N1E-115 neuroblastoma cell line was switched into a neuronal phenotype by DMSO treatment and used for proteomic experiments. We used two-dimensional gel electrophoresis followed by unambiguous mass spectrometrical identification of proteins to generate a map of cytoskeleton proteins (CPs), i.e., to search for differentiation-related structures. Alpha-actin, actin-like protein 6A, gamma-tubulin complex component 2, tubulin alpha 3/alpha 7, CLIP associating protein 2, B4 integrin interactor homolog were detectable in the undifferentiated cell line exclusively and neuron-specific CPs drebrin and presynaptic density protein 95, actin-related protein 2/3, alpha and beta-centractin, PDZ-domain actin binding protein, actinin alpha 1, profilin II, ezrin, coactosin-like protein, transgelin 2, myosin light polypeptide 6, tubulin alpha 2, 6 and 7, beta tubulin (94% similar with tubulin beta-2), tubulin beta 3, tubulin tyrosine ligase-like protein 1, lamin B1 and keratin 20 were observed in the differentiated cell line only. We herein identified differentiation-related expressional patterns thus providing new evidence for the role of CPs in the process of neuronal differentiation.

Development and validation of method for TH588 and TH287, potent MTH1 inhibitors and new anti-cancer agents, for pharmacokinetic studies in mice plasma.

PubMed

Saleh, Aljona; Gökturk, Camilla; Warpman-Berglund, Ulrika; Helleday, Thomas; Granelli, Ingrid

2015-02-01

MTH1 is a protein that is required for cancer cell survival and is overexpressed in cancer cells. TH588 and TH287 are two new compounds that inhibit the MTH1 protein. The inhibitors were tested in pharmacokinetic studies on mice. A bioanalytical method was developed and validated for determination in mice plasma. The method was based on protein precipitation followed by LC-MS/MS analysis. The separation was performed on an Ascentis Express RP-Amide C18 column. The mass spectrometer was operated in positive electrospray ionization mode and the analytes were determined with multiple reaction monitoring (MRM). Abundant monoisotopic fragments were used for quantification. Two additional fragments were used for conformational analysis. The recovery of the compounds in plasma varied between 61 and 91% and the matrix effects were low and ranged between -3% and +2%. The method showed to be selective, linear, accurate and precise, and applicable for preclinical pharmacokinetic studies of TH588 and TH287 in mouse plasma. Half-life (T1/2) was ≤3.5h and maximum concentration (Cmax) ranged between 0.82 and 338μM for the different administration routes and compounds. Copyright © 2014 Elsevier B.V. All rights reserved.

TESTING THE BLACK HOLE NO-HAIR THEOREM WITH OJ287

DOE Office of Scientific and Technical Information (OSTI.GOV)

Valtonen, M. J.; Mikkola, S.; Lehto, H. J.

2011-11-20

We examine the ability to test the black hole no-hair theorem at the 10% level in this decade using the binary black hole in OJ287. In the test we constrain the value of the dimensionless parameter q that relates the scaled quadrupole moment and spin of the primary black hole: q{sub 2} = -q {chi}{sup 2}. At the present we can say that q = 1 {+-} 0.3 (1{sigma}), in agreement with general relativity and the no-hair theorems. We demonstrate that this result can be improved if more observational data are found in historical plate archives for the 1959 andmore » 1971 outbursts. We also show that the predicted 2015 and 2019 outbursts will be crucial in improving the accuracy of the test. Space-based photometry is required in 2019 July due the proximity of OJ287 to the Sun at the time of the outburst. The best situation would be to carry out the photometry far from the Earth, from quite a different vantage point, in order to avoid the influence of the nearby Sun. We have considered in particular the STEREO space mission, which would be ideal if it has a continuation in 2019, or the Long Range Reconnaissance Imager on board the New Horizons mission to Pluto.« less

25 CFR 115.703 - May we accept for deposit into a trust account money not specified in § 115.702?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false May we accept for deposit into a trust account money not specified in § 115.702? 115.703 Section 115.703 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES TRUST FUNDS FOR TRIBES AND INDIVIDUAL INDIANS Trust Fund Accounts: General Information § 115.703 May we accept for...

Employing Electron Microscopy integrated with X-ray Spectroscopy for Kuntawa Landslide Assessment

NASA Astrophysics Data System (ADS)

Dikedi, P. N.

2016-12-01

This work centres on Kuntawa landslide assessment owing to the enigmatic nature of a 2003 landslide which buried 4 people and a truck in Kuntawa village, of Nigeria. A Phenom ProX Scanning Electron Microscope (SEM) integrated with Energy dispersive X-ray Spectroscopy (EDS) and Particlemetric software was employed to generate the morphology, particle size data, elemental identification data and topography (at 3500x) of earth samples scooped from the landslide site. For a core sample 1 at depth, d=3.75m, average circle equivalent diameter dav, area a and volume by area Va of 11.5 µm, 249 µm² and 3680µm³ were generated respectively; at d=3.785m, dav , a and Va of 6.19µm, 30.1µm² and 124µm³ were generated respectively; at d=3.82m, dav , a and Va of 11.5 µm, 130 µm² and 1380µm³ were generated respectively. For a core sample 2, at d=3.75m, dav, a and Va of 5.54 µm, 26 µm² and 108µm³ were generated respectively; at d=3.82m, dav , a and Va of 19.4µm, 338µm² and 5240µm³ were generated respectively; a total of 243 particles were scanned. One of the results from specific surface for samples 1 and 2, reveals that it would take twice and four times the amount of water needed to wet an entire surface both at d=3.82m than at d=3.785m and d=3.75m respectively. Additional laboratory facilities reveal that soil water content Š, volumetric water content Vwc, porosity Φ, soil water-filled pore space Wps, increased with increasing d; bulk density ρb, decreased with increasing d. Elemental composition at the landslide site were generated from the EDS: oxygen (O), Silicon (Si), Bromine (Br), iron (Fe), Carbon (C) and Aluminium (Al). O and C had the highest and lowest concentration of elemental compositions of 68.5% at 3.75m depth and 1% at 3.82m depth for samples 1 and 2, respectively. Keywords: EDS, Particlemetric, SEM.

Mix or un-mix? Trace element segregation from a heterogeneous mantle, simulated.

NASA Astrophysics Data System (ADS)

Katz, R. F.; Keller, T.; Warren, J. M.; Manley, G.

2016-12-01

Incompatible trace-element concentrations vary in mid-ocean ridge lavas and melt inclusions by an order of magnitude or more, even in samples from the same location. This variability has been attributed to channelised melt flow [Spiegelman & Kelemen, 2003], which brings enriched, low-degree melts to the surface in relative isolation from depleted inter-channel melts. We re-examine this hypothesis using a new melting-column model that incorporates mantle volatiles [Keller & Katz 2016]. Volatiles cause a deeper onset of channelisation: their corrosivity is maximum at the base of the silicate melting regime. We consider how source heterogeneity and melt transport shape trace-element concentrations in basaltic lavas. We use both equilibrium and non-equilibrium formulations [Spiegelman 1996]. In particular, we evaluate the effect of melt transport on probability distributions of trace element concentration, comparing the inflow distribution in the mantle with the outflow distribution in the magma. Which features of melt transport preserve, erase or overprint input correlations between elements? To address this we consider various hypotheses about mantle heterogeneity, allowing for spatial structure in major components, volatiles and trace elements. Of interest are the roles of wavelength, amplitude, and correlation of heterogeneity fields. To investigate how different modes of melt transport affect input distributions, we compare melting models that produce either shallow or deep channelisation, or none at all.References:Keller & Katz (2016). The Role of Volatiles in Reactive Melt Transport in the Asthenosphere. Journal of Petrology, http://doi.org/10.1093/petrology/egw030. Spiegelman (1996). Geochemical consequences of melt transport in 2-D: The sensitivity of trace elements to mantle dynamics. Earth and Planetary Science Letters, 139, 115-132. Spiegelman & Kelemen (2003). Extreme chemical variability as a consequence of channelized melt transport. Geochemistry Geophysics Geosystems, http://doi.org/10.1029/2002GC000336

Oxysterol-binding protein-related protein (ORP) 9 is a PDK-2 substrate and regulates Akt phosphorylation.

PubMed

Lessmann, Eva; Ngo, Mike; Leitges, Michael; Minguet, Susana; Ridgway, Neale D; Huber, Michael

2007-02-01

The oxysterol-binding protein and oxysterol-binding protein-related protein family has been implicated in lipid transport and metabolism, vesicle trafficking and cell signaling. While investigating the phosphorylation of Akt/protein kinase B in stimulated bone marrow-derived mast cells, we observed that a monoclonal antibody directed against phospho-S473 Akt cross-reacted with oxysterol-binding protein-related protein 9 (ORP9). Further analysis revealed that mast cells exclusively express ORP9S, an N-terminal truncated version of full-length ORP9L. A PDK-2 consensus phosphorylation site in ORP9L and OPR9S at S287 (VPEFS(287)Y) was confirmed by site-directed mutagenesis. In contrast to Akt, increased phosphorylation of ORP9S S287 in stimulated mast cells was independent of phosphatidylinositol 3-kinase but sensitive to inhibition of conventional PKC isotypes. PKC-beta dependence was confirmed by lack of ORP9S phosphorylation at S287 in PKC-beta-deficient, but not PKC-alpha-deficient, mast cells. Moreover, co-immunoprecipitation of PKC-beta and ORP9S, and in vitro phosphorylation of ORP9S in this complex, argued for direct phosphorylation of ORP9S by PKC-beta, introducing ORP9S as a novel PKC-beta substrate. Akt was also detected in a PKC-beta/ORP9S immune complex and phosphorylation of Akt on S473 was delayed in PKC-deficient mast cells. In HEK293 cells, RNAi experiments showed that depletion of ORP9L increased Akt S473 phosphorylation 3-fold without affecting T308 phosphorylation in the activation loop. Furthermore, mammalian target of rapamycin was implicated in ORP9L phosphorylation in HEK293 cells. These studies identify ORP9 as a PDK-2 substrate and negative regulator of Akt phosphorylation at the PDK-2 site.

Concentrations and source apportionment of PM10 and associated elemental and ionic species in a lignite-burning power generation area of southern Greece.

PubMed

Argyropoulos, G; Grigoratos, Th; Voutsinas, M; Samara, C

2013-10-01

Ambient concentrations of PM10 and associated elemental and ionic species were measured over the cold and the warm months of 2010 at an urban and two rural sites located in the lignite-fired power generation area of Megalopolis in Peloponnese, southern Greece. The PM10 concentrations at the urban site (44.2 ± 33.6 μg m(-3)) were significantly higher than those at the rural sites (23.7 ± 20.4 and 22.7 ± 26.9 μg m(-3)). Source apportionment of PM10 and associated components was accomplished by an advanced computational procedure, the robotic chemical mass balance model (RCMB), using chemical profiles for a variety of local fugitive dust sources (power plant fly ash, flue gas desulfurization wet ash, feeding lignite, infertile material from the opencast mines, paved and unpaved road dusts, soil), which were resuspended and sampled through a PM10 inlet onto filters and then chemically analyzed, as well as of other common sources such as vehicular traffic, residential oil combustion, biomass burning, uncontrolled waste burning, marine aerosol, and secondary aerosol formation. Geological dusts (road/soil dust) were found to be major PM10 contributors in both the cold and warm periods of the year, with average annual contribution of 32.6 % at the urban site vs. 22.0 and 29.0 % at the rural sites. Secondary aerosol also appeared to be a significant source, contributing 22.1 % at the urban site in comparison to 30.6 and 28.7 % at the rural sites. At all sites, the contribution of biomass burning was most significant in winter (28.2 % at the urban site vs. 14.6 and 24.6 % at the rural sites), whereas vehicular exhaust contribution appeared to be important mostly in the summer (21.9 % at the urban site vs. 11.5 and 10.5 % at the rural sites). The highest contribution of fly ash (33.2 %) was found at the rural site located to the north of the power plants during wintertime, when winds are favorable. In the warm period, the highest contribution of fly ash was found at the rural site located to the south of the power plants, although it was less important (7.2 %). Moderate contributions of fly ash were found at the urban site (5.4 and 2.7 % in the cold and the warm period, respectively). Finally, the mine field was identified as a minor PM10 source, occasionally contributing with lignite dust and/or deposited wet ash dust under dry summer conditions, with the summertime contributions ranging between 3.1 and 11.0 % among the three sites. The non-parametric bootstrapped potential source contribution function analysis was further applied to localize the regions of sources apportioned by the RCMB. For the majority of sources, source regions appeared as being located within short distances from the sampling sites (within the Peloponnesse Peninsula). More distant Greek areas of the NNE sector also appeared to be source regions for traffic emissions and secondary calcium sulfate dust.

Chemical quality and temperature of water in Flaming Gorge Reservoir, Wyoming and Utah, and the effect of the reservoir on the Green River

USGS Publications Warehouse

Bolke, E.L.; Waddell, Kidd M.

1975-01-01

The major tributaries to Flaming Gorge Reservoir contribute an average of about 97 percent of the total streamflow and 82 percent of the total load of dissolved solids. The Green River is the largest tributary, and for the 1957-72 water years it contributed 81 percent of the total streamflow and 70 percent of the total load of dissolved solids. The principal constituents in the tributary streamflow are calcium and sulfate during periods of lowest flow and calcium and bicarbonate during periods of highest flow.Flaming Gorge Dam was closed in November 1962, and the most significant load changes of chemical constituents due to the net effect of inflow, outflow, leaching, and chemical precipitation in the reservoir have been load changes of sulfate and bicarbonate. The average increase of dissolved load of sulfate in the reservoir for the 1969-72 water years was 110,000 tons (99,790 t) per year, which was 40,000 tons (36,287 t) per year less than for the 1963-66 water years. The average decrease of dissolved load of bicarbonate in the reservoir for 1969-72 was 40,000 tons (36,287 t) per year, which was the same as the decrease for 1963-66.Anaerobic conditions were observed in the deep, uncirculated part of the reservoir near the dam during the 1971 and 1972 water years, and anaerobic or near-anaerobic conditions were observed near the confluence of the Blacks Fork and Green River during the summers of 1971 and 1972.The water in Flaming Gorge Reservoir is in three distinct layers, and the upper two layers (the epilimnion and the metalimnion) mixed twice during each of the 1971-72 water years. The two circulation periods were in the spring and fall. The water in the deepest layer (the hypolimnion) did not mix with the waters of the upper zones because the density difference was too great and because the deep, narrow shape of the basin probably inhibits mixing.The depletion of flow in the Green River downstream from Flaming Gorge Dam between closure of the dam and the end of the 1972 water year was 4,500,000 acre-feet (5,550.8 hm3). Of this total, water stored in the reservoir accounted for 3,500,000 acre-feet (4,317.2 hm3), evaporation consumed 700,000 acre-feet (863.4 hm3), and 300,000 acre-feet (370.0 hm3) went into bank storage.The net load of dissolved solids added to the river system during the 1963-72 water years, due to leaching and chemical precipitation, was 1,730,000 tons (1,569,421 t). The leaching rate was 200,000 tons (181,436 t) per year for 1963-68,115,000 tons (104,326 t) per year for 1969-70 and 150,000 tons (136,077 t) per year for 1971-72. It appears that the leaching rates should decrease in the future since the reservoir level in 1972 was near maximum pool level.The most significant increase in concentration of the chemical constituents in the water below the reservoir involved the sulfate ion, which increased from about 115 milligrams per litre (42 percent of the anions) in 1957 to about 200 milligrams per litre (54 percent), in 1972. But the highest concentration, about 290 milligrams per litre (58 percent), occurred in 1963, immediately after closure of the dam.Prior to closure of the dam, the average monthly temperature of the Green River below the damsite ranged from 0°C to 19.5°C as compared to 3.5°C to 10.0°C after closure.

Evaluation of matrix effect on the determination of rare earth elements and As, Bi, Cd, Pb, Se and In in honey and pollen of native Brazilian bees (Tetragonisca angustula - Jataí) by Q-ICP-MS.

PubMed

de Oliveira, Fernanda Ataide; de Abreu, Adriana Trópia; de Oliveira Nascimento, Nathália; Froes-Silva, Roberta Eliane Santos; Antonini, Yasmine; Nalini, Hermínio Arias; de Lena, Jorge Carvalho

2017-01-01

Bees are considered the main pollinators in natural and agricultural environments. Chemical elements from honey and pollen have been used for monitoring the environment, the health of bees and the quality of their products. Nevertheless, there are not many studies on honey and pollen of native Brazilian bees. The goal of this work was to determine important chemical elements (Sc, Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Dy, Ho, Er, Tm, Lu and Yb) along with As, Bi, Cd, Pb, Se and In, in honey and pollen of native Brazilian bees, assessing analytical interferences from the matrix. A proposed analytical method was developed for these elements by quadrupole ICP-MS. Matrix effect was verified in honey matrix in the quantification of As, Bi and Dy; and in pollen matrix for Bi, Cd, Ce, Gd, La, Pb and Sc. The quality of the method was considered satisfactory taking into consideration the recovery rate of each element in the spiked solutions: honey matrix (91.6-103.9%) and pollen matrix (94.1-115.6%). The quantification limits of the method ranged between 0.00041 and 10.3μgL -1 for honey and 0.00041-0.095μgL -1 for pollen. The results demonstrate that the method is accurate, precise and suitable. Copyright © 2016 Elsevier B.V. All rights reserved.

Mass concentration and elemental composition of indoor PM 2.5 and PM 10 in University rooms in Thessaloniki, northern Greece

NASA Astrophysics Data System (ADS)

Gemenetzis, Panagiotis; Moussas, Panagiotis; Arditsoglou, Anastasia; Samara, Constantini

The mass concentration and the elemental composition of PM 2.5 and PM 10 were measured in 40 rooms (mainly offices or mixed office-lab rooms, and photocopying places) of the Aristotle University of Thessaloniki, northern Greece. A total of 27 major, minor and trace elements were determined by ED-XRF analysis. The PM 2.5/PM 10 concentration ratios averaged 0.8±0.2, while the corresponding elemental ratios ranged between 0.4±0.2 and 0.9±0.2. The concentrations of PM 2.5 and PM 10 were significantly higher (by 70% and 50%, respectively) in the smokers' rooms compared to the non-smokers' places. The total elemental concentrations were also higher in the smokers' rooms (11.5 vs 8.2 μg m -3 for PM 2.5, and 10.3 vs 7.6 μg m -3 for PM 2.5-10). Fine particle concentrations (PM 2.5) were found to be quite proportional to smoking strength. On the contrary, the two environments exhibited similar coarse (PM 2.5-10) particle fractions not related to the number of cigarettes smoked. A slight decrease of particle concentrations with increasing the floor level was also observed, particularly for PM 2.5, suggesting that high-level floors are less impacted by near ground-level sources like traffic emissions. Finally, the removal efficiency of air purification systems was evaluated.

The microwave induced plasma with optical emission spectrometry (MIP-OES) in 23 elements determination in geological samples.

PubMed

Niedzielski, P; Kozak, L; Wachelka, M; Jakubowski, K; Wybieralska, J

2015-01-01

The article presents the optimisation, validation and application of the microwave induced plasma optical emission spectrometry (MIP-OES) dedicated for a routine determination of Ag, Al, B, Ba, Bi, Ca, Cd, Cr, Cu, Fe, Ga, In, K, Li, Mg, Mn, Mo, Na, Ni, Pb, Sr, Tl, Zn, in the geological samples. The three procedures of sample preparation has been proposed: sample digestion with the use of hydrofluoric acid for determination of total concentration of elements, extraction by aqua regia for determination of the quasi-total element concentration and extraction by hydrochloric acid solution to determine contents of the elements in acid leachable fraction. The detection limits were on the level 0.001-0.121 mg L(-1) (from 0.010-0.10 to 1.2-12 mg kg(-1) depend on the samples preparation procedure); the precision: 0.20-1.37%; accuracy 85-115% (for recovery for certified standards materials analysis and parallel analysis by independent analytical techniques: X-ray fluorescence (XRF) and flame absorption spectrometry (FAAS)). The conformity of the results obtained by MIP-OES analytical procedures with the results obtained by XRF and FAAS analysis allows to propose the procedures for studies of elemental composition of the fraction of the geological samples. Additionally, the MIP-OES technique is much less expensive than ICP techniques and much less time-consuming than AAS techniques. Copyright © 2014 Elsevier B.V. All rights reserved.

GOLGI FRACTIONS PREPARED FROM RAT LIVER HOMOGENATES

PubMed Central

Ehrenreich, J. H.; Bergeron, J. J. M.; Siekevitz, P.; Palade, G. E.

1973-01-01

In devising a new procedure for the isolation of Golgi fractions from rat liver homogenates, we have taken advantage of the overloading with very low density lipoprotein (VLDL) particles that occurs in the Golgi elements of hepatocytes ∼90 min after ethanol is administered (0.6 g/100 g body weight) by stomach tube to the animals. The VLDLs act as morphological markers as well as density modifiers of these elements. The starting preparation is a total microsomal fraction prepared from liver homogenized (1:5) in 0.25 M sucrose. This fraction is resuspended in 1.15 M sucrose and loaded at the bottom of a discontinuous sucrose density gradient. Centrifugation at ∼13 x 106 g·min yields by flotation three Golgi fractions of density >1.041 and <1.173. The light and intermediate fractions consist essentially of VLDL-loaded Golgi vacuoles and cisternae. Nearly empty, often collapsed, Golgi cisternae are the main component of the heavy fraction. A procedure which subjects the Golgi fractions to hypotonic shock and shearing in a French press at pH 8.5 allows the extraction of the content of the Golgi elements and the subsequent isolation of their membranes by differential centrifugation. PMID:4356571

Crohn's disease in adolescence: presentation and treatment.

PubMed

Cullen, Mick; Barnes, Claire

2015-05-13

Crohn's disease is a chronic inflammatory bowel condition that affects more than 115,000 people in the UK. This article focuses on Crohn's disease in adolescents. Management of the condition in this group should address adolescent-specific characteristics and treatment goals. Key elements include optimising growth, pubertal development and social functioning, including education. The condition can affect an individual's mental and emotional wellbeing significantly, as well as their physical health. As adolescence is a time of great change, the additional burden of a chronic illness can prove difficult to manage. The authors provide information on the presentation of Crohn's disease in adolescence and insights into the particular issues encountered by this group.

Stress strain modelling and analysis of a piezo-coated optical fibre sensor

NASA Astrophysics Data System (ADS)

Al-Raweshidy, H.; Ali, H.; Obayya, S. S. A.; Langley, R.; Batchelor, J.

2005-02-01

A finite element model, using commercially available software, is presented to simulate the piezoelectrically induced stresses and strains in an optical fibre to be used as antenna. These stresses and strains are generated by a layer of piezoelectric polymer deposited on the cladding of a short fibre sample. The theoretical basis for the work is briefly explained and the modelling process is emphasised. Two types of fibre are investigated - circular fibre and D-fibre, and the results compared, analysed and discussed. It is shown that in the D-fibre, the stress and displacement increased by 1.46 and 115 times, respectively, in comparison with the circular fibre.

24 CFR 115.307 - Requirements for participation in the FHAP; Corrective and remedial action for failing to comply...

Code of Federal Regulations, 2013 CFR

2013-04-01

... the FHAP; Corrective and remedial action for failing to comply with requirements. 115.307 Section 115... § 115.307 Requirements for participation in the FHAP; Corrective and remedial action for failing to... to the requirements of § 115.311. (b) Corrective and remedial action for failing to comply with...

24 CFR 115.307 - Requirements for participation in the FHAP; Corrective and remedial action for failing to comply...

Code of Federal Regulations, 2011 CFR

2011-04-01

... the FHAP; Corrective and remedial action for failing to comply with requirements. 115.307 Section 115... § 115.307 Requirements for participation in the FHAP; Corrective and remedial action for failing to... to the requirements of § 115.311. (b) Corrective and remedial action for failing to comply with...

24 CFR 115.307 - Requirements for participation in the FHAP; Corrective and remedial action for failing to comply...

Code of Federal Regulations, 2012 CFR

2012-04-01

... the FHAP; Corrective and remedial action for failing to comply with requirements. 115.307 Section 115... § 115.307 Requirements for participation in the FHAP; Corrective and remedial action for failing to... to the requirements of § 115.311. (b) Corrective and remedial action for failing to comply with...

24 CFR 115.307 - Requirements for participation in the FHAP; Corrective and remedial action for failing to comply...

Code of Federal Regulations, 2010 CFR

2010-04-01

... the FHAP; Corrective and remedial action for failing to comply with requirements. 115.307 Section 115... § 115.307 Requirements for participation in the FHAP; Corrective and remedial action for failing to... to the requirements of § 115.311. (b) Corrective and remedial action for failing to comply with...

24 CFR 115.307 - Requirements for participation in the FHAP; Corrective and remedial action for failing to comply...

Code of Federal Regulations, 2014 CFR

2014-04-01

... the FHAP; Corrective and remedial action for failing to comply with requirements. 115.307 Section 115... § 115.307 Requirements for participation in the FHAP; Corrective and remedial action for failing to... to the requirements of § 115.311. (b) Corrective and remedial action for failing to comply with...

46 CFR 28.115 - Ring life buoys.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Ring life buoys. 28.115 Section 28.115 Shipping COAST... VESSELS Requirements for All Vessels § 28.115 Ring life buoys. (a) Except as provided in paragraph (b) of... life buoy as specified in table 28.115. If the vessel is equipped with a ring life buoy, at least one...

46 CFR 28.115 - Ring life buoys.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Ring life buoys. 28.115 Section 28.115 Shipping COAST... VESSELS Requirements for All Vessels § 28.115 Ring life buoys. (a) Except as provided in paragraph (b) of... life buoy as specified in table 28.115. If the vessel is equipped with a ring life buoy, at least one...

46 CFR 28.115 - Ring life buoys.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Ring life buoys. 28.115 Section 28.115 Shipping COAST... VESSELS Requirements for All Vessels § 28.115 Ring life buoys. (a) Except as provided in paragraph (b) of... life buoy as specified in table 28.115. If the vessel is equipped with a ring life buoy, at least one...

46 CFR 28.115 - Ring life buoys.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 1 2014-10-01 2014-10-01 false Ring life buoys. 28.115 Section 28.115 Shipping COAST... VESSELS Requirements for All Vessels § 28.115 Ring life buoys. (a) Except as provided in paragraph (b) of... life buoy as specified in table 28.115. If the vessel is equipped with a ring life buoy, at least one...

46 CFR 28.115 - Ring life buoys.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Ring life buoys. 28.115 Section 28.115 Shipping COAST... VESSELS Requirements for All Vessels § 28.115 Ring life buoys. (a) Except as provided in paragraph (b) of... life buoy as specified in table 28.115. If the vessel is equipped with a ring life buoy, at least one...

25 CFR 115.800 - When does OTFM open a tribal account?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false When does OTFM open a tribal account? 115.800 Section 115... TRIBES AND INDIVIDUAL INDIANS Tribal Accounts § 115.800 When does OTFM open a tribal account? A tribal account is opened when OTFM receives income from the sources described in § 115.702. ...

Nuclear Factor Kappa B Activation and Peroxisome Proliferator-activated Receptor Transactivational Effects of Chemical Components of the Roots of Polygonum multiflorum.

PubMed

Sun, Ya Nan; Li, Wei; Song, Seok Bean; Yan, Xi Tao; Yang, Seo Young; Kim, Young Ho

2016-01-01

Polygonum multiflorum is well-known as "Heshouwu" in traditional Chinese herbal medicine. In Northeast Asia, it is often used as a tonic to prevent premature aging of the kidney and liver, tendons, and bones and strengthening of the lower back and knees. To research the anti-inflammatory activities of components from P. multiflorum. The compounds were isolated by a combination of silica gel and YMC R-18 column chromatography, and their structures were identified by analysis of spectroscopic data (1D, 2D-nuclear magnetic resonance, and mass spectrometry). The anti-inflammatory activities of the isolated compounds 1-15 were evaluated by luciferase reporter gene assays. Fifteen compounds (1-15) were isolated from the roots of P. multiflorum. Compounds 1-5 and 14-15 significantly inhibited tumor necrosis factor-α-induced nuclear factor kappa B-luciferase activity, with IC50 values of 24.16-37.56 μM. Compounds 1-5 also greatly enhanced peroxisome proliferator-activated receptors transcriptional activity with EC50 values of 18.26-31.45 μM. The anthraquinone derivatives were the active components from the roots of P. multiflorum as an inhibitor on inflammation-related factors in human hepatoma cells. Therefore, we suggest that the roots of P. multiflorum can be used to treat natural inflammatory diseases. This study presented that fifteen compounds (1-15) isolated from the roots of Polygonum multiflrum exert signifiant anti inflmmatory effects by inhibiting TNF α induced NF κB activation and PPARs transcription. Abbreviation used: NF κB: Nuclear factor kappa B, PPARs: Peroxisome proliferator activated receptors, PPREs: Peroxisome proliferator response elements, TNF α: Tumor necrosis factor α, ESI-MS: Electrospray ionization mass spectrometry, HepG2: Human hepatoma cells.

40 CFR 60.287a - Recordkeeping.

Code of Federal Regulations, 2014 CFR

2014-07-01

... furnace, digester system, brown stock washer system, multiple-effect evaporator system, or condensate... digester system, brown stock washer system, multiple effect evaporator system, or condensate stripper...

The potential of on-line continuous leach ICP-MS analysis for linking trace elements to mineralogy

NASA Astrophysics Data System (ADS)

Roskam, Gerlinde; Verheul, Marc; Moraetis, Daniel; Giannakis, George; van Gaans, Pauline

2014-05-01

A set of five soil samples was subjected to an on-line continuous leach inductively coupled plasma mass spectrometry experiment, with progressively reactive solvents (0.01M CaCl2, 0.1 M HNO3, 1M HNO3, 4M HNO3) Each sample was packed in a quartz tube (Ø= 1 cm, length 2 cm) and diluted 1:1 with acid washed quartz to prevent clogging. The gas that was produced during the extraction was removed by leading the effluent into a small container, from where the sample was directly pumped into the ICP-MS. 115In was used as an internal standard. Continuous leach experiments have the advantage of real time (every 2 seconds) full elemental analysis. Mineral breakdown reactions can be monitored via the major elements. The trace elements associated with the minerals are monitored simultaneously, thus eliminating the uncertainties of host mineral-trace element combinations in traditional off-line sequential extractions. The continuous leach experimental data are correlated to XRD-results for mineralogy and total elemental concentrations. The soil samples used were collected from different sites in the Koiliaris River watershed, Crete, Greece 1). The selection of the sites was based on variability in bedrock (limestone, metamorphic and alluvial sediments) and current land use (grape farming, olive trees). Soils were sampled at two depths: at the surface and just above the bedrock. No large differences in the major elements between the two depths were measured. To provide background to the on-line sequential data, also total concentrations of the major elements were analysed by XRF and the mineralogy was analysed by XRD. The fraction <2mm was sieved and digested with HF, HClO4 and HNO3 for additional trace element analysis. 1) See related abstract Roskam et al., 2014: REE profiles in continuous leach ICP-MS (CL-ICP-MS) experiments in soil, linked to REE profiles in surface water in the Koiliaris River Critical Zone Observatory (CZO), Crete, Greece.

The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae.

PubMed

Gross, Roy; Guzman, Carlos A; Sebaihia, Mohammed; dos Santos, Vítor A P Martins; Pieper, Dietmar H; Koebnik, Ralf; Lechner, Melanie; Bartels, Daniela; Buhrmester, Jens; Choudhuri, Jomuna V; Ebensen, Thomas; Gaigalat, Lars; Herrmann, Stefanie; Khachane, Amit N; Larisch, Christof; Link, Stefanie; Linke, Burkhard; Meyer, Folker; Mormann, Sascha; Nakunst, Diana; Rückert, Christian; Schneiker-Bekel, Susanne; Schulze, Kai; Vorhölter, Frank-Jörg; Yevsa, Tetyana; Engle, Jacquelyn T; Goldman, William E; Pühler, Alfred; Göbel, Ulf B; Goesmann, Alexander; Blöcker, Helmut; Kaiser, Olaf; Martinez-Arias, Rosa

2008-09-30

Bordetella petrii is the only environmental species hitherto found among the otherwise host-restricted and pathogenic members of the genus Bordetella. Phylogenetically, it connects the pathogenic Bordetellae and environmental bacteria of the genera Achromobacter and Alcaligenes, which are opportunistic pathogens. B. petrii strains have been isolated from very different environmental niches, including river sediment, polluted soil, marine sponges and a grass root. Recently, clinical isolates associated with bone degenerative disease or cystic fibrosis have also been described. In this manuscript we present the results of the analysis of the completely annotated genome sequence of the B. petrii strain DSMZ12804. B. petrii has a mosaic genome of 5,287,950 bp harboring numerous mobile genetic elements, including seven large genomic islands. Four of them are highly related to the clc element of Pseudomonas knackmussii B13, which encodes genes involved in the degradation of aromatics. Though being an environmental isolate, the sequenced B. petrii strain also encodes proteins related to virulence factors of the pathogenic Bordetellae, including the filamentous hemagglutinin, which is a major colonization factor of B. pertussis, and the master virulence regulator BvgAS. However, it lacks all known toxins of the pathogenic Bordetellae. The genomic analysis suggests that B. petrii represents an evolutionary link between free-living environmental bacteria and the host-restricted obligate pathogenic Bordetellae. Its remarkable metabolic versatility may enable B. petrii to thrive in very different ecological niches.

Mapping Henry: Synchrotron-sourced X-ray fluorescence mapping and ultra-high-definition scanning of an early Tudor portrait of Henry VIII

NASA Astrophysics Data System (ADS)

Dredge, Paula; Ives, Simon; Howard, Daryl L.; Spiers, Kathryn M.; Yip, Andrew; Kenderdine, Sarah

2015-11-01

A portrait of Henry VIII on oak panel c. 1535 has recently undergone technical examination to inform questions regarding authorship and the painting's relationship to a group of similar works in the collections of the National Portrait Gallery, London, and the Society of Antiquaries. Due to previous conservation treatments of the painting, the conventional transmission X-radiograph image was difficult to interpret. As a result, the painting underwent high-definition X-ray fluorescence (XRF) elemental mapping on the X-ray fluorescence microscopy beamline of the Australian Synchrotron. Scans were conducted at 12.6 and 18.5 keV, below and above the lead (Pb) L edges, respectively. Typical scan parameters were 120 μm pixel size at 7 ms dwell time, with the largest scan covering an area 545 × 287 mm2 collected in 23 h (10.8 MP). XRF mapping of the panel has guided the conservation treatment of the painting and the revelation of previously obscured features. It has also provided insight into the process of making of the painting. The informative and detailed elemental maps, alongside ultra-high-definition scans of the painting undertaken before and after varnish and over-paint removal, have assisted in comparison of the finely painted details with the London paintings. The resolution offered by the combination of imaging techniques identifies pigment distribution at an extremely fine scale, enabling a new understanding of the artist's paint application.

Ambient air quality at the wider area of an industrial mining facility at Stratoni, Chalkidiki, Greece.

PubMed

Gaidajis, Georgios; Angelakoglou, Komninos; Gazea, Emmy

2012-01-01

To assess ambient air quality at the wider area of a mining-industrial facility in Chalkidiki, Greece, the particulate matter with an aerodynamic diameter of 10 μm (PM(10)) and its content in characteristic elements, i.e., As, Cd, Cu, Fe, Mn, Pb, Zn were monitored for a period of three years (2008-2010). Gravimetric air samplers were employed for the particulate matter sampling at three sampling stations located in the immediate vicinity of the industrial facility and at a neighbouring residential site. Monitoring data indicated that the 3-year median PM(10) concentrations were 23.3 μg/m(3) at the residential site close to the facility and 28.7 μg/m(3) at the site within the facility indicating a minimal influence from the industrial activities to the air quality of the neighbouring residential area. Both annual average and median PM(10) concentration levels were below the indicative European standards, whereas similar spatial and temporal variation was observed for the PM(10) constituents. The average Pb concentrations measured for the three sampling sites were 0.2, 0.146 and 0.174 μg/m(3) respectively, well below the indicative limit of 0.5 μg/m(3). The quantitative and qualitative comparison of PM(10) concentrations and its elemental constituent for the three sampling stations did not indicate any direct influence of the mining-industrial activities to the air quality of the Stratoni residential area.

The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae

PubMed Central

Gross, Roy; Guzman, Carlos A; Sebaihia, Mohammed; Martins dos Santos, Vítor AP; Pieper, Dietmar H; Koebnik, Ralf; Lechner, Melanie; Bartels, Daniela; Buhrmester, Jens; Choudhuri, Jomuna V; Ebensen, Thomas; Gaigalat, Lars; Herrmann, Stefanie; Khachane, Amit N; Larisch, Christof; Link, Stefanie; Linke, Burkhard; Meyer, Folker; Mormann, Sascha; Nakunst, Diana; Rückert, Christian; Schneiker-Bekel, Susanne; Schulze, Kai; Vorhölter, Frank-Jörg; Yevsa, Tetyana; Engle, Jacquelyn T; Goldman, William E; Pühler, Alfred; Göbel, Ulf B; Goesmann, Alexander; Blöcker, Helmut; Kaiser, Olaf; Martinez-Arias, Rosa

2008-01-01

Background Bordetella petrii is the only environmental species hitherto found among the otherwise host-restricted and pathogenic members of the genus Bordetella. Phylogenetically, it connects the pathogenic Bordetellae and environmental bacteria of the genera Achromobacter and Alcaligenes, which are opportunistic pathogens. B. petrii strains have been isolated from very different environmental niches, including river sediment, polluted soil, marine sponges and a grass root. Recently, clinical isolates associated with bone degenerative disease or cystic fibrosis have also been described. Results In this manuscript we present the results of the analysis of the completely annotated genome sequence of the B. petrii strain DSMZ12804. B. petrii has a mosaic genome of 5,287,950 bp harboring numerous mobile genetic elements, including seven large genomic islands. Four of them are highly related to the clc element of Pseudomonas knackmussii B13, which encodes genes involved in the degradation of aromatics. Though being an environmental isolate, the sequenced B. petrii strain also encodes proteins related to virulence factors of the pathogenic Bordetellae, including the filamentous hemagglutinin, which is a major colonization factor of B. pertussis, and the master virulence regulator BvgAS. However, it lacks all known toxins of the pathogenic Bordetellae. Conclusion The genomic analysis suggests that B. petrii represents an evolutionary link between free-living environmental bacteria and the host-restricted obligate pathogenic Bordetellae. Its remarkable metabolic versatility may enable B. petrii to thrive in very different ecological niches. PMID:18826580

Synthesis of Superheavy Nuclei in 48CA-INDUCED Reactions

NASA Astrophysics Data System (ADS)

Oganessian, Yu. Ts.; Utyonkov, V. K.; Lobanov, Yu. V.; Abdullin, F. Sh.; Polyakov, A. N.; Sagaidak, R. N.; Shirokovsky, I. V.; Tsyganov, Yu. S.; Voinov, A. A.; Gulbekian, G. G.; Bogomolov, S. L.; Gikal, B. N.; Mezentsev, A. N.; Iliev, S.; Subbotin, V. G.; Sukhov, A. M.; Subotic, K.; Zagrebaev, V. I.; Vostokin, G. K.; Itkis, M. G.; Moody, K. J.; Patin, J. B.; Shaughnessy, D. A.; Stoyer, M. A.; Stoyer, N. J.; Wilk, P. A.; Kenneally, J. M.; Landrum, J. H.; Wild, J. F.; Lougheed, R. W.

2008-11-01

Thirty-four new nuclides with Z = 104-116, 118 and N = 161-177 have been synthesized in the complete-fusion reactions of 238U, 237Np, 242,244Pu, 243Am, 245,248Cm, and 249Cf targets with 48Ca beams. The masses of evaporation residues were identified through measurements of the excitation functions of the xn-evaporation channels and from cross bombardments. The decay properties of the new nuclei agree with those of previously known heavy nuclei and with predictions from different theoretical models. A discussion of self-consistent interpretations of all observed decay chains originating from the parent isotopes 282,283112, 282113, 286-289114, 287,288115, 290-293116, and 294118 is presented. Decay energies and lifetimes of the neutron-rich superheavy nuclei as well as their production cross sections indicate a considerable increase in the stability of nuclei with an increasing number of neutrons, which agrees with the predictions of theoretical models concerning the decisive dependence of the structure and radioactive properties of superheavy elements on their proximity to the nuclear shells with N = 184 and Z = 114.

High Resolution Spectroscopy of AGN in Outburst: The Gaseous Nuclear Environment and the WIGM

NASA Technical Reports Server (NTRS)

Mushotzky, Richard (Technical Monitor); Nicastro, Fabrizio

2004-01-01

This grant is associated to a successful XMM-A02 proposal to observe blazars in outburst states, to X-ray the intergalactic medium, searching for intervening ionized absorption. The observation was triggered on August 31 2003, on the blazar 1H 0414+009 (2=0.287), when the target was showing a level of activity of about 20 mCrab in the total XTE-ASM band. The observation was performed 1 day later (on September 1, 2003) and lasted for 79 ks (79 % of the requested time). Unfortunately, assuming that the XTE-ASM notification was real, the target had recovered his quiescent level of approx. 0.35 mCrab, when the XMM RGS observed it. This, combined with the lower-than-requested exposure, produced an XMM-RGS spectrum containing only - 40 counts per resolution element in the 24.1 less than lambda(A) less than 30 range, insufficient to detect even the strongest predicted lines from the OVII WHIM. However, we do detect the Local Group WHIM OVII system in the spectrum of this blazar.

Design of Raft Foundations for High-Rise Buildings on Jointed Rock

NASA Astrophysics Data System (ADS)

Justo, J. L.; García-Núñez, J.-C.; Vázquez-Boza, M.; Justo, E.; Durand, P.; Azañón, J. M.

2014-07-01

This paper presents calculations of displacements and bending moments in a 2-m-thick reinforced-concrete foundation slab using three-dimensional finite-element software. A preliminary paper was presented by Justo et al. (Rock Mech Rock Eng 43:287-304, 2010). The slab is the base of a tower of 137 m height above foundation, supported on jointed and partly weathered basalt and scoria. Installation of rod extensometers at different depths below foundation allowed comparison between measured displacements and displacements calculated using moduli obtained from rock classification systems and three material models: elastic, Mohr-Coulomb and hardening (H). Although all three material models can provide acceptable results, the H model is preferable when there are unloading processes. Acceptable values of settlement may be achieved with medium meshing and an approximate distribution of loads. The absolute values of negative bending moments (tensions below) increase as the rock mass modulus decreases or when the mesh is refined. The paper stresses the importance of adequately representing the details of the distribution of loads and the necessity for fine meshing to obtain acceptable values of bending moments.

Precise measurement of energy of the first excited state of 115Sn (Eexc ≃ 497.3 keV)

NASA Astrophysics Data System (ADS)

Zheltonozhsky, V. A.; Savrasov, A. M.; Strilchuk, N. V.; Tretyak, V. I.

2018-01-01

Single beta decay of 115In to the first excited level of 115Sn (E\\text{exc}≃ 497.3 \\text{keV} ) is known as β-decay with the lowest Qβ value. To determine the Qβ precisely, one has to measure very accurately the E\\text{exc} value. A sample of tin enriched in 115Sn to 50.7% was irradiated by a proton beam at the U-120 accelerator of INR, Kyiv. The 115Sb radioactive isotope, created in the 115Sn(p,n)115Sb reaction, decays with T1/2 = 32 \\text{min} to 115Sn populating the 497 keV level with ≃ 96{%} probability. The total statistics of ˜105 counts collected in the 497 keV peak in a series of measurements, the exact description of the peak shape and the precisely known calibration points around the 497 keV peak allowed to obtain the value E\\text{exc}= 497.342(3) \\text{keV} , which is the most precise to-date. This leads to the following Qβ\\ast value for the decay 115In → 115Sn*: Qβ\\ast= 147 +/- 10 \\text{eV} .

28 CFR 115.173 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false [Reserved] 115.173 Section 115.173 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Investigations § 115.173 [Reserved] Discipline ...

28 CFR 115.173 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false [Reserved] 115.173 Section 115.173 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Investigations § 115.173 [Reserved] Discipline ...

28 CFR 115.173 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false [Reserved] 115.173 Section 115.173 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Investigations § 115.173 [Reserved] Discipline ...

A Dual Polarized Quasi-Optical SIS Mixer at 550-GHz

NASA Technical Reports Server (NTRS)

Chattopadhyay, Goutam; Miller, David; LeDuc, Henry G.; Zmuidzinas, Jonas

2000-01-01

We describe the design, fabrication, and the performance of a low-noise dual-polarized quasi-optical superconductor insulator superconductor (SIS) mixer at 550 GHz. The mixer utilizes a novel cross-slot antenna on a hyperhemispherical substrate lens, two junction tuning circuits, niobium trilayer junctions, and an IF circuit containing a lumped element 180 deg hybrid. The antenna consists of an orthogonal pair of twin-slot antennas, and has four feed points, two for each polarization. Each feed point is coupled to a two-junction SIS mixer. The 180 deg IF hybrid is implemented using a lumped element/microstrip circuit located inside the mixer block. Fourier transform spectrometer (FTS) measurements of the mixer frequency response show good agreement with computer simulations. The measured co-polarized and cross-polarized patterns for both polarizations also agree with the theoretical predictions. The noise performance of the dual-polarized mixer is excellent, giving uncorrected receiver noise temperature of better than 115 K (DSB) at 528 GHz for both the polarizations.

Magnetic properties of doped Mn-Ga alloys made by mechanical milling and heat treatment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Daniel R.; National High Magnetic Field Laboratory, Tallahassee, FL 32310; Han, Ke

2016-05-15

Mn-Ga alloys have shown hard magnetic properties, even though these alloys contain no rare-earth metals. However, much work is needed before rare-earth magnets can be replaced. We have examined the magnetic properties of bulk alloys made with partial replacement of both the Mn and Ga elements in the Mn{sub 0.8}Ga{sub 0.2} system. Bulk samples of Mn-Ga-Bi, Mn-Ga-Al, Mn-Fe-Ga and Mn-(FeB)-Ga alloys were fabricated and studied using mechanically milling and heat treatments while altering the atomic percentage of the third element between 2.5 and 20 at%. The ternary alloy exhibits all hard magnetic properties at room temperature with large coercivity. Annealedmore » Mn-Ga-X bulk composites exhibit high coercivities up to 16.6 kOe and remanence up to 9.8 emu/g, that is increased by 115% over the binary system.« less

Mercury and trace element distribution in density separates of a South African Highveld (#4) coal: Implications for mercury reduction and preparation of export coal

USGS Publications Warehouse

Kolker, Allan; Senior, Connie L.; van Alphen, Chris; Koenig, Alan E.; Geboy, Nicholas J.

2017-01-01

Eight density separates of Permian Highveld (#4) coal were investigated for partitioning of Hg and trace elements. The separates include float fractions obtained in heavy media having densities of 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, and 2.0 g/cm3, and the sink fraction for 2.0 g/cm3. Bulk analysis of the separates shows strong (R2 ≥ 0.80) positive correlations between pyritic sulfur and mercury, and between ash yield and both pyritic sulfur and mercury. Laser ablation (LA) ICP-MS analysis of individual pyrite grains in the separates confirms association of Hg and As with pyrite as indicated by bulk analysis. Other elements detected in pyrite by LA-ICP-MS include Mn, Co, Ni, Tl, and Pb. Results for the separates allow prediction of Hg, trace elements, and ash yields expected in specific South African coal products. These range from 0.06 ppm Hg and an ash yield of 11.5% ash for the export fraction to 0.47 ppm Hg and an ash yield of 60.9% for the discard (stone) fraction (dry basis). Results show pronounced differences expected between coal used for domestic power generation and coal which is exported.

Minor elements incorporation control by ionic radius and growth rate on a stalagmite from the Chauvet Cave (SE-France)

NASA Astrophysics Data System (ADS)

Bourdin, C.; Douville, E.; Genty, D.

2009-12-01

A multi-elemental study focusing on earth-alkalis (Mg, Ca, Sr and Ba), uranium and rare-earth elements (REE) in the calcite of a stalagmite from the Chauvet Cave (SE of France) has been achieved by ICP-MS. The Chau-stm6 stalagmite which grew from 33 to 11.5 ky had already been dated and the published d13C and d18O profile is used as a paleoclimatic benchmark. Ba and Sr profiles show an abrupt concentration increase at the beginning of the last deglaciation whereas U and Mg feature a decreasing trend. REY (REE+yttrium) concentrations decrease markedly during early deglaciation (between 15 and 14.5 ky). The transition corresponds to a change from a slow to a fast growth rate. These variations can be explained by the crystallographic control of ionic radii of the minor elements: incorporation of small ions compared to Ca such as U, Mg, heavy REE are favoured during slow growth period (i.e. glacial) whereas large ions such as Ba, Sr and light REE are preferentially precipitated during fast growth period (i.e. Bolling-Allerod). This crystallographic effect seems to be dominant here because the soil above the cave is sparse. And may not have played a major role on the opposite to the water-limestone interaction.

Concentrations of arsenic and other elements in groundwater of Bangladesh and West Bengal, India: potential cancer risk.

PubMed

Rahman, Mohammad Mahmudur; Dong, Zhaomin; Naidu, Ravi

2015-11-01

We investigated the concentrations of 23 elements in groundwater from arsenic (As) contaminated areas of Bangladesh and West Bengal, India to determine the potential human exposure to metals and metalloids. Elevated concentrations of As was found in all five study areas that exceeded the World Health Organization (WHO) guideline value of 10μg/L. The mean As concentrations in groundwater of Noakhali, Jalangi and Domkal, Dasdia Nonaghata, Deganga and Baruipur were 297μg/L, 262μg/L, 115μg/L, 161μg/L and 349μg/L, respectively. Elevated concentrations of Mn were also detected in all areas with mean concentrations were 139μg/L, 807μg/L, 341μg/L, 579μg/L and 584μg/L for Noakhali, Jalangi and Domkal, Dasdia Nonaghata, Deganga and Baruipur, respectively. Daily As intakes from drinking water for adults and the potential cancer risk for all areas was also estimated. Results suggest that mitigation activities such as water treatment should not only be focused on As but must also consider other elements including Mn, B and Ba. The groundwater used for public drinking purposes needs to be tested periodically for As and other elements to ensure the quality of drinking water is within the prescribed national guidelines. Copyright © 2015 Elsevier Ltd. All rights reserved.

28 CFR 115.133 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false [Reserved] 115.133 Section 115.133 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Training and Education § 115.133 [Reserved] ...

28 CFR 115.314 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false [Reserved] 115.314 Section 115.314 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Prevention Planning § 115.314 [Reserved] ...

28 CFR 115.314 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false [Reserved] 115.314 Section 115.314 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Prevention Planning § 115.314 [Reserved] ...

28 CFR 115.133 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false [Reserved] 115.133 Section 115.133 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Training and Education § 115.133 [Reserved] ...

28 CFR 115.133 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false [Reserved] 115.133 Section 115.133 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Training and Education § 115.133 [Reserved] ...

28 CFR 115.314 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false [Reserved] 115.314 Section 115.314 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Prevention Planning § 115.314 [Reserved] ...

42 CFR 488.115 - Care guidelines.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 5 2010-10-01 2010-10-01 false Care guidelines. 488.115 Section 488.115 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... § 488.115 Care guidelines. EC01JA91.110 EC01JA91.111 EC01JA91.112 EC01JA91.113 EC01JA91.114 EC01JA91.115...

28 CFR 115.251 - Resident reporting.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Resident reporting. 115.251 Section 115.251 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Reporting § 115.251 Resident reporting. (a) The...

28 CFR 115.251 - Resident reporting.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Resident reporting. 115.251 Section 115.251 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Reporting § 115.251 Resident reporting. (a) The...

28 CFR 115.134 - Specialized training: Investigations.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Specialized training: Investigations. 115.134 Section 115.134 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Training and Education § 115.134 Specialized training...

28 CFR 115.252 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Exhaustion of administrative remedies. 115.252 Section 115.252 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Reporting § 115.252...

28 CFR 115.134 - Specialized training: Investigations.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Specialized training: Investigations. 115.134 Section 115.134 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Training and Education § 115.134 Specialized training...

28 CFR 115.134 - Specialized training: Investigations.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Specialized training: Investigations. 115.134 Section 115.134 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Training and Education § 115.134 Specialized training...

28 CFR 115.251 - Resident reporting.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Resident reporting. 115.251 Section 115.251 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Reporting § 115.251 Resident reporting. (a) The...

28 CFR 115.252 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Exhaustion of administrative remedies. 115.252 Section 115.252 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Reporting § 115.252...

28 CFR 115.252 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Exhaustion of administrative remedies. 115.252 Section 115.252 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Reporting § 115.252...

7 CFR 1150.115 - Research.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 9 2013-01-01 2013-01-01 false Research. 1150.115 Section 1150.115 Agriculture... AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.115 Research. Research means studies testing the effectiveness of market...

7 CFR 1150.115 - Research.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 9 2010-01-01 2009-01-01 true Research. 1150.115 Section 1150.115 Agriculture... and Orders; Milk), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.115 Research. Research means studies testing the effectiveness of market...

7 CFR 1150.115 - Research.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 9 2012-01-01 2012-01-01 false Research. 1150.115 Section 1150.115 Agriculture... and Orders; Milk), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.115 Research. Research means studies testing the effectiveness of market...

7 CFR 1150.115 - Research.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 9 2014-01-01 2013-01-01 true Research. 1150.115 Section 1150.115 Agriculture... AND ORDERS; MILK), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.115 Research. Research means studies testing the effectiveness of market...

7 CFR 1150.115 - Research.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 9 2011-01-01 2011-01-01 false Research. 1150.115 Section 1150.115 Agriculture... and Orders; Milk), DEPARTMENT OF AGRICULTURE DAIRY PROMOTION PROGRAM Dairy Promotion and Research Order Definitions § 1150.115 Research. Research means studies testing the effectiveness of market...

28 CFR 115.213 - Supervision and monitoring.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Supervision and monitoring. 115.213 Section 115.213 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Prevention Planning § 115.213 Supervision...

28 CFR 115.213 - Supervision and monitoring.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Supervision and monitoring. 115.213 Section 115.213 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Prevention Planning § 115.213 Supervision...

28 CFR 115.213 - Supervision and monitoring.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Supervision and monitoring. 115.213 Section 115.213 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Prevention Planning § 115.213 Supervision...

Characterization of tub4P287L, a β‐tubulin mutant, revealed new aspects of microtubule regulation in shade

PubMed Central

Yu, Jie; Qiu, Hong; Liu, Xin; Wang, Meiling; Gao, Yongli; Chory, Joanne

2015-01-01

Abstract When sun plants, such as Arabidopsis thaliana, are under canopy shade, elongation of stems/petioles will be induced as one of the most prominent responses. Plant hormones mediate the elongation growth. However, how environmental and hormonal signals are translated into cell expansion activity that leads to the elongation growth remains elusive. Through forward genetic study, we identified shade avoidance2 (sav2) mutant, which contains a P287L mutation in β‐TUBULIN 4. Cortical microtubules (cMTs) play a key role in anisotropic cell growth. Hypocotyls of sav2 are wild type‐like in white light, but are short and highly swollen in shade and dark. We showed that shade not only induces cMT rearrangement, but also affects cMT stability and dynamics of plus ends. Even though auxin and brassinosteroids are required for shade‐induced hypocotyl elongation, they had little effect on shade‐induced rearrangement of cMTs. Blocking auxin transport suppressed dark phenotypes of sav2, while overexpressing EB1b‐GFP, a microtubule plus‐end binding protein, rescued sav2 in both shade and dark, suggesting that tub4P287L represents a unique type of tubulin mutation that does not affect cMT function in supporting cell elongation, but may affect the ability of cMTs to respond properly to growth promoting stimuli. PMID:25899068

Brain-Derived Neurotrophic Factor Signaling Rewrites the Glucocorticoid Transcriptome via Glucocorticoid Receptor Phosphorylation

PubMed Central

Lambert, W. Marcus; Xu, Chong-Feng; Neubert, Thomas A.; Chao, Moses V.

2013-01-01

Abnormal glucocorticoid and neurotrophin signaling has been implicated in numerous psychiatric disorders. However, the impact of neurotrophic signaling on glucocorticoid receptor (GR)-dependent gene expression is not understood. We therefore examined the impact of brain-derived neurotrophic factor (BDNF) signaling on GR transcriptional regulatory function by gene expression profiling in primary rat cortical neurons stimulated with the selective GR agonist dexamethasone (Dex) and BDNF, alone or in combination. Simultaneous treatment with BDNF and Dex elicited a unique set of GR-responsive genes associated with neuronal growth and differentiation and also enhanced the induction of a large number of Dex-sensitive genes. BDNF via its receptor TrkB enhanced the transcriptional activity of a synthetic GR reporter, suggesting a direct effect of BDNF signaling on GR function. Indeed, BDNF treatment induces the phosphorylation of GR at serine 155 (S155) and serine 287 (S287). Expression of a nonphosphorylatable mutant (GR S155A/S287A) impaired the induction of a subset of BDNF- and Dex-regulated genes. Mechanistically, BDNF-induced GR phosphorylation increased GR occupancy and cofactor recruitment at the promoter of a BDNF-enhanced gene. GR phosphorylation in vivo is sensitive to changes in the levels of BDNF and TrkB as well as stress. Therefore, BDNF signaling specifies and amplifies the GR transcriptome through a coordinated GR phosphorylation-dependent detection mechanism. PMID:23878391

The transcription factor MYB115 contributes to the regulation of proanthocyanidin biosynthesis and enhances fungal resistance in poplar.

PubMed

Wang, Lijun; Ran, Lingyu; Hou, Yisu; Tian, Qiaoyan; Li, Chaofeng; Liu, Rui; Fan, Di; Luo, Keming

2017-07-01

Proanthocyanidins (PAs) are major defense phenolic compounds in the leaves of poplar (Populus spp.) in response to abiotic and biotic stresses. Transcriptional regulation of PA biosynthetic genes by the MYB-basic helix-loop-helix (bHLH)-WD40 complexes in poplar is not still fully understood. Here, an Arabidopsis TT2-like gene MYB115 was isolated from Populus tomentosa and characterized by various molecular, genetic and biochemical approaches. MYB115 restored PA productions in the seed coat of the Arabidopsis tt2 mutant. Overexpression of MYB115 in poplar activated expression of PA biosynthetic genes, resulting in a significant increase in PA concentrations. By contrast, the CRISPR/Cas9-generated myb115 mutant exhibited reduced PA content and decreased expression of PA biosynthetic genes. MYB115 directly activated the promoters of PA-specific structural genes. MYB115 interacted with poplar TT8. Coexpression of MYB115, TT8 and poplar TTG1 significantly enhanced the expression of ANR1 and LAR3. Additionally, transgenic plants overexpressing MYB115 had increased resistance to the fungal pathogen Dothiorella gregaria, whereas myb115 mutant exhibited greater sensitivity compared with wild-type plants. Our data provide insight into the regulatory mechanisms controlling PA biosynthesis by MYB115 in poplar, which could be effectively employed for metabolic engineering of PAs to improve resistance to fungal pathogens. No claim to original Chinese Government works New Phytologist © 2017 New Phytologist Trust.

GEMS and New Pre-Accretionally Irradiated RELICT Grains in Interplanetary Dust - The Plot Thickens

NASA Astrophysics Data System (ADS)

Bradley, J.

1995-09-01

The hypothesis that GEMS (glass with embedded metal and sulfides) in interplanetary dust particles (IDPs) might be the long-sought interstellar silicate grains is undergoing close scrutiny [1-3]. GEMS are proposed to be interstellar because: (a) they are abundant in cometary IDPs; (b) they were irradiated prior to incorporation into IDPs; (c) both their size distribution and Oamorphous silicate" microstructures are consistent with those of interstellar silicates; (d) they contain nanometer-sized (superparamagnetic) alpha-iron inclusions, which provides a simple explanation for the observed interstellar grain alignment and polarization [4,5]. Challenges to the GEMS hypothesis include the following: (a) GEMS may have formed and been irradiated in the solar nebula rather than a presolar interstellar environment; (b) non-solar isotope abundances have yet to be measured in GEMS; (c) the irradiation regime required to produce the observed effects in GEMS might be incompatible with the interstellar medium; (b) relationships between GEMS and carbon (e.g. core/mantle) need clarification; (c) major element abundances in GEMS should be consistent with observed interstellar gas phase depletions [2,3]. GEMS may indeed have formed in the solar nebula, in which case they would be the oldest known solar nebula solids [2]. An interstellar origin for GEMS does not require detection of non-solar isotope abundances [6]. Irradiation experiments are in progress to simulate the properties of GEMS. The petrographic relationship between GEMS and carbon in IDPs is being investigated (by examining IDPs embedded and thin-sectioned in carbon-free media). Major element abundances in GEMS are being evaluated in terms on interstellar gas phase abundances. For example, sulfur is not highly depleted in the interstellar gas, implying that it must be significantly depleted in interstellar grains [3]. GEMS are significantly depleted in sulfur relative to solar abundances. Analytical electron microscopic studies of the local petrographic environment of GEMS in IDPs are continuing. There is evidence of a population of relict grains associated with GEMS. Some of these relict grains have distinctive compositions and they appear to have functioned as (pre-existing) depositional substrates while GEMS were being formed. Thus, it may be possible to begin to assign a chronology to the seemingly complex admixture of grains that make up the ultrafine-grained matrices of anhydrous chondritic IDPs. References: [1] Bradley J. P. (1994) Science, 265, 925-929. [2] Flynn G. J. (1994) Nature, 371, 287-288. [3] Martin P. G. (1995) Astrophys. J., 445, L63-L66. [4] Mathis J. S. (1986) Astrophys. J., 308, 281-287. [5] Mathis J. S. (1993) Rept. Prog. Phys., 56, 605-652. [6] Walker R. M. (1994) in Analysis of Interplanetary Dust (M. E. Zolensky et al., eds.), pp. 203-209, AIP Conf. Proc. 310.

28 CFR 115.13 - Supervision and monitoring.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Supervision and monitoring. 115.13 Section 115.13 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Prevention Planning § 115.13 Supervision and...

28 CFR 115.34 - Specialized training: Investigations.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Specialized training: Investigations. 115.34 Section 115.34 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Training and Education § 115.34...

28 CFR 115.151 - Detainee reporting.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Detainee reporting. 115.151 Section 115.151 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Reporting § 115.151 Detainee reporting. (a) The agency shall provide...

28 CFR 115.351 - Resident reporting.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Resident reporting. 115.351 Section 115.351 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Reporting § 115.351 Resident reporting. (a) The agency shall...

28 CFR 115.402 - Auditor qualifications.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Auditor qualifications. 115.402 Section 115.402 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Auditing and Corrective Action § 115.402 Auditor qualifications. (a) An audit shall be conducted...

28 CFR 115.273 - Reporting to residents.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Reporting to residents. 115.273 Section 115.273 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Investigations § 115.273 Reporting to residents. (a...

28 CFR 115.273 - Reporting to residents.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Reporting to residents. 115.273 Section 115.273 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Investigations § 115.273 Reporting to residents. (a...

28 CFR 115.135 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false [Reserved] 115.135 Section 115.135 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Training and Education § 115.135 [Reserved] Screening for Risk of Sexual Victimization...

28 CFR 115.34 - Specialized training: Investigations.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Specialized training: Investigations. 115.34 Section 115.34 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Training and Education § 115.34...

28 CFR 115.151 - Detainee reporting.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Detainee reporting. 115.151 Section 115.151 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Reporting § 115.151 Detainee reporting. (a) The agency shall provide...

28 CFR 115.351 - Resident reporting.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Resident reporting. 115.351 Section 115.351 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Reporting § 115.351 Resident reporting. (a) The agency shall...

28 CFR 115.372 - Evidentiary standard for administrative investigations.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Evidentiary standard for administrative investigations. 115.372 Section 115.372 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Investigations § 115.372 Evidentiary...

28 CFR 115.352 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Exhaustion of administrative remedies. 115.352 Section 115.352 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Reporting § 115.352 Exhaustion of...

28 CFR 115.271 - Criminal and administrative agency investigations.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Criminal and administrative agency investigations. 115.271 Section 115.271 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Investigations § 115.271...

28 CFR 115.402 - Auditor qualifications.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Auditor qualifications. 115.402 Section 115.402 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Auditing and Corrective Action § 115.402 Auditor qualifications. (a) An audit shall be conducted...

28 CFR 115.135 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false [Reserved] 115.135 Section 115.135 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Training and Education § 115.135 [Reserved] Screening for Risk of Sexual Victimization...

28 CFR 115.402 - Auditor qualifications.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Auditor qualifications. 115.402 Section 115.402 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Auditing and Corrective Action § 115.402 Auditor qualifications. (a) An audit shall be conducted...

28 CFR 115.272 - Evidentiary standard for administrative investigations.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Evidentiary standard for administrative investigations. 115.272 Section 115.272 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Investigations § 115.272...

28 CFR 115.352 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Exhaustion of administrative remedies. 115.352 Section 115.352 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Reporting § 115.352 Exhaustion of...

28 CFR 115.373 - Reporting to residents.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Reporting to residents. 115.373 Section 115.373 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Investigations § 115.373 Reporting to residents. (a) Following...

28 CFR 115.351 - Resident reporting.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Resident reporting. 115.351 Section 115.351 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Reporting § 115.351 Resident reporting. (a) The agency shall...

28 CFR 115.272 - Evidentiary standard for administrative investigations.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Evidentiary standard for administrative investigations. 115.272 Section 115.272 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Investigations § 115.272...

28 CFR 115.372 - Evidentiary standard for administrative investigations.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Evidentiary standard for administrative investigations. 115.372 Section 115.372 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Investigations § 115.372 Evidentiary...

28 CFR 115.65 - Coordinated response.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Coordinated response. 115.65 Section 115.65 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Official Response Following An Inmate Report § 115.65...

28 CFR 115.254 - Third-party reporting.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Third-party reporting. 115.254 Section 115.254 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Reporting § 115.254 Third-party reporting. The...

28 CFR 115.254 - Third-party reporting.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Third-party reporting. 115.254 Section 115.254 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Reporting § 115.254 Third-party reporting. The...

28 CFR 115.373 - Reporting to residents.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Reporting to residents. 115.373 Section 115.373 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Investigations § 115.373 Reporting to residents. (a) Following...

28 CFR 115.273 - Reporting to residents.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Reporting to residents. 115.273 Section 115.273 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Investigations § 115.273 Reporting to residents. (a...

28 CFR 115.65 - Coordinated response.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Coordinated response. 115.65 Section 115.65 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Official Response Following An Inmate Report § 115.65...

28 CFR 115.34 - Specialized training: Investigations.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Specialized training: Investigations. 115.34 Section 115.34 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Training and Education § 115.34...

28 CFR 115.135 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false [Reserved] 115.135 Section 115.135 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Training and Education § 115.135 [Reserved] Screening for Risk of Sexual Victimization...

28 CFR 115.373 - Reporting to residents.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Reporting to residents. 115.373 Section 115.373 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Investigations § 115.373 Reporting to residents. (a) Following...

28 CFR 115.65 - Coordinated response.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Coordinated response. 115.65 Section 115.65 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Official Response Following An Inmate Report § 115.65...

28 CFR 115.272 - Evidentiary standard for administrative investigations.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Evidentiary standard for administrative investigations. 115.272 Section 115.272 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Investigations § 115.272...

28 CFR 115.352 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Exhaustion of administrative remedies. 115.352 Section 115.352 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Reporting § 115.352 Exhaustion of...

28 CFR 115.271 - Criminal and administrative agency investigations.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Criminal and administrative agency investigations. 115.271 Section 115.271 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Investigations § 115.271...

28 CFR 115.254 - Third-party reporting.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Third-party reporting. 115.254 Section 115.254 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Reporting § 115.254 Third-party reporting. The...

28 CFR 115.151 - Detainee reporting.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Detainee reporting. 115.151 Section 115.151 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Reporting § 115.151 Detainee reporting. (a) The agency shall provide...

28 CFR 115.271 - Criminal and administrative agency investigations.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Criminal and administrative agency investigations. 115.271 Section 115.271 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Investigations § 115.271...

28 CFR 115.372 - Evidentiary standard for administrative investigations.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Evidentiary standard for administrative investigations. 115.372 Section 115.372 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Investigations § 115.372 Evidentiary...

13 CFR 115.34 - Minimization of Surety's Loss.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Minimization of Surety's Loss. 115.34 Section 115.34 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SURETY BOND GUARANTEE... strategy in maximizing recovery. See also § 115.17(b). ...

44 CFR 19.115 - Assurance required.

Code of Federal Regulations, 2010 CFR

2010-10-01

... RECEIVING FEDERAL FINANCIAL ASSISTANCE Introduction § 19.115 Assurance required. (a) General. Either at the... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Assurance required. 19.115 Section 19.115 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF...

48 CFR 49.115 - Settlement of terminated incentive contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Settlement of terminated incentive contracts. 49.115 Section 49.115 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS General Principles 49.115 Settlement of terminated...

28 CFR 115.13 - Supervision and monitoring.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Supervision and monitoring. 115.13 Section 115.13 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Prevention Planning § 115.13 Supervision and...

28 CFR 115.13 - Supervision and monitoring.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Supervision and monitoring. 115.13 Section 115.13 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Prevention Planning § 115.13 Supervision and...

24 CFR 115.206 - Performance assessments; Performance standards.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false Performance assessments; Performance standards. 115.206 Section 115.206 Housing and Urban Development Regulations Relating to Housing... AGENCIES Certification of Substantially Equivalent Agencies § 115.206 Performance assessments; Performance...

24 CFR 115.206 - Performance assessments; Performance standards.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Performance assessments; Performance standards. 115.206 Section 115.206 Housing and Urban Development Regulations Relating to Housing... AGENCIES Certification of Substantially Equivalent Agencies § 115.206 Performance assessments; Performance...

24 CFR 115.206 - Performance assessments; Performance standards.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Performance assessments; Performance standards. 115.206 Section 115.206 Housing and Urban Development Regulations Relating to Housing... AGENCIES Certification of Substantially Equivalent Agencies § 115.206 Performance assessments; Performance...

24 CFR 115.206 - Performance assessments; Performance standards.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Performance assessments; Performance standards. 115.206 Section 115.206 Housing and Urban Development Regulations Relating to Housing... AGENCIES Certification of Substantially Equivalent Agencies § 115.206 Performance assessments; Performance...

24 CFR 115.206 - Performance assessments; Performance standards.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Performance assessments; Performance standards. 115.206 Section 115.206 Housing and Urban Development Regulations Relating to Housing... AGENCIES Certification of Substantially Equivalent Agencies § 115.206 Performance assessments; Performance...

24 CFR 245.115 - Protected activities.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Protected activities. 245.115 Section 245.115 Housing and Urban Development Regulations Relating to Housing and Urban Development... TENANT PARTICIPATION IN MULTIFAMILY HOUSING PROJECTS Tenant Organizations § 245.115 Protected activities...

24 CFR 245.115 - Protected activities.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Protected activities. 245.115 Section 245.115 Housing and Urban Development Regulations Relating to Housing and Urban Development... TENANT PARTICIPATION IN MULTIFAMILY HOUSING PROJECTS Tenant Organizations § 245.115 Protected activities...

24 CFR 245.115 - Protected activities.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Protected activities. 245.115 Section 245.115 Housing and Urban Development Regulations Relating to Housing and Urban Development... TENANT PARTICIPATION IN MULTIFAMILY HOUSING PROJECTS Tenant Organizations § 245.115 Protected activities...

24 CFR 245.115 - Protected activities.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Protected activities. 245.115 Section 245.115 Housing and Urban Development Regulations Relating to Housing and Urban Development... TENANT PARTICIPATION IN MULTIFAMILY HOUSING PROJECTS Tenant Organizations § 245.115 Protected activities...

40 CFR 1054.115 - What other requirements apply?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 33 2014-07-01 2014-07-01 false What other requirements apply? 1054.115 Section 1054.115 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Emission Standards and Related Requirements § 1054.115 What other requirements apply? The following...

Structural and Functional Characterization of a Novel Family GH115 4-O-Methyl-α-Glucuronidase with Specificity for Decorated Arabinogalactans.

PubMed

Aalbers, Friso; Turkenburg, Johan P; Davies, Gideon J; Dijkhuizen, Lubbert; Lammerts van Bueren, Alicia

2015-12-04

Glycoside hydrolases are clustered into families based on amino acid sequence similarities, and belonging to a particular family can infer biological activity of an enzyme. Family GH115 contains α-glucuronidases where several members have been shown to hydrolyze terminal α-1,2-linked glucuronic acid and 4-O-methylated glucuronic acid from the plant cell wall polysaccharide glucuronoxylan. Other GH115 enzymes show no activity on glucuronoxylan, and therefore, it has been proposed that family GH115 may be a poly-specific family. In this study, we reveal that a putative periplasmic GH115 from the human gut symbiont Bacteroides thetaiotaomicron, BtGH115A, hydrolyzes terminal 4-O-methyl-glucuronic acid residues from decorated arabinogalactan isolated from acacia tree. The three-dimensional structure of BtGH115A reveals that BtGH115A has the same domain architecture as the other structurally characterized member of this family, BoAgu115A; however the position of the C-terminal module is altered with respect to each individual enzyme. Phylogenetic analysis of GH115 amino sequences divides the family into distinct clades that may distinguish different substrate specificities. Finally, we show that BtGH115A α-glucuronidase activity is necessary for the sequential digestion of branched galactans from acacia gum by a galactan-β-1,3-galactosidase from family GH43; however, while B. thetaiotaomicron grows on larch wood arabinogalactan, the bacterium is not able to metabolize acacia gum arabinogalactan, suggesting that BtGH115A is involved in degradation of arabinogalactan fragments liberated by other microbial species in the gastrointestinal tract. Copyright © 2015 Elsevier Ltd. All rights reserved.

41 CFR 115-1.110 - Deviations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Deviations. 115-1.110 Section 115-1.110 Public Contracts and Property Management Federal Property Management Regulations System (Continued) ENVIRONMENTAL PROTECTION AGENCY 1-INTRODUCTION 1.1-Regulation System § 115-1.110 Deviations...

46 CFR 150.115 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 5 2011-10-01 2011-10-01 false Definitions. 150.115 Section 150.115 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.115 Definitions. As used in this subpart: Hazardous material means: (a) A flammable liquid...

46 CFR 150.115 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 5 2013-10-01 2013-10-01 false Definitions. 150.115 Section 150.115 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.115 Definitions. As used in this subpart: Hazardous material means: (a) A flammable liquid...

46 CFR 150.115 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 5 2014-10-01 2014-10-01 false Definitions. 150.115 Section 150.115 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.115 Definitions. As used in this subpart: Hazardous material means: (a) A flammable liquid...

46 CFR 150.115 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 5 2010-10-01 2010-10-01 false Definitions. 150.115 Section 150.115 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.115 Definitions. As used in this subpart: Hazardous material means: (a) A flammable liquid...

46 CFR 150.115 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 5 2012-10-01 2012-10-01 false Definitions. 150.115 Section 150.115 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.115 Definitions. As used in this subpart: Hazardous material means: (a) A flammable liquid...

4 CFR 28.115 - Processing petitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 4 Accounts 1 2010-01-01 2010-01-01 false Processing petitions. 28.115 Section 28.115 Accounts... Special Procedures; Representation Proceedings § 28.115 Processing petitions. (a) Upon the expiration of... their consultations including an agreement on the appropriate units, on the withdrawal of the petition...

21 CFR 211.115 - Reprocessing.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 4 2013-04-01 2013-04-01 false Reprocessing. 211.115 Section 211.115 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Production and Process Controls § 211.115...

21 CFR 211.115 - Reprocessing.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Reprocessing. 211.115 Section 211.115 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Production and Process Controls § 211.115...

21 CFR 211.115 - Reprocessing.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Reprocessing. 211.115 Section 211.115 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Production and Process Controls § 211.115...

21 CFR 211.115 - Reprocessing.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Reprocessing. 211.115 Section 211.115 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Production and Process Controls § 211.115...

21 CFR 211.115 - Reprocessing.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 4 2014-04-01 2014-04-01 false Reprocessing. 211.115 Section 211.115 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Production and Process Controls § 211.115...

28 CFR 0.115 - General functions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false General functions. 0.115 Section 0.115 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE Executive Office for Immigration Review § 0.115 General functions. (a) The Executive Office for Immigration Review...

7 CFR 1221.115 - Investment of funds.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Investment of funds. 1221.115 Section 1221.115 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... Information Board § 1221.115 Investment of funds. The Board may invest, pending disbursement, funds it...

6 CFR 27.115 - Implementation.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 6 Domestic Security 1 2012-01-01 2012-01-01 false Implementation. 27.115 Section 27.115 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS General § 27.115 Implementation. The Assistant Secretary may implement the section 550 program in...

6 CFR 27.115 - Implementation.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 6 Domestic Security 1 2011-01-01 2011-01-01 false Implementation. 27.115 Section 27.115 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS General § 27.115 Implementation. The Assistant Secretary may implement the section 550 program in...

6 CFR 27.115 - Implementation.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 6 Domestic Security 1 2013-01-01 2013-01-01 false Implementation. 27.115 Section 27.115 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS General § 27.115 Implementation. The Assistant Secretary may implement the section 550 program in...

6 CFR 27.115 - Implementation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 6 Domestic Security 1 2010-01-01 2010-01-01 false Implementation. 27.115 Section 27.115 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS General § 27.115 Implementation. The Assistant Secretary may implement the Section 550 program in...

6 CFR 27.115 - Implementation.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 6 Domestic Security 1 2014-01-01 2014-01-01 false Implementation. 27.115 Section 27.115 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS General § 27.115 Implementation. The Assistant Secretary may implement the section 550 program in...

7 CFR 1221.115 - Investment of funds.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Investment of funds. 1221.115 Section 1221.115 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... Information Board § 1221.115 Investment of funds. The Board may invest, pending disbursement, funds it...

28 CFR 115.73 - Reporting to inmates.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Reporting to inmates. 115.73 Section 115.73 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Investigations § 115.73 Reporting to inmates. (a) Following...

28 CFR 115.114 - Juveniles and youthful detainees.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Juveniles and youthful detainees. 115.114 Section 115.114 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Prevention Planning § 115.114 Juveniles and youthful detainees...

28 CFR 115.72 - Evidentiary standard for administrative investigations.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Evidentiary standard for administrative investigations. 115.72 Section 115.72 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Investigations § 115.72 Evidentiary...

28 CFR 115.293 - Audits of standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Audits of standards. 115.293 Section 115.293 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Audits § 115.293 Audits of standards. The agency...

28 CFR 115.293 - Audits of standards.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Audits of standards. 115.293 Section 115.293 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Community Confinement Facilities Audits § 115.293 Audits of standards. The agency...

28 CFR 115.14 - Youthful inmates.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Youthful inmates. 115.14 Section 115.14 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Prevention Planning § 115.14 Youthful inmates. (a) A youthful inmate...

28 CFR 115.51 - Inmate reporting.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Inmate reporting. 115.51 Section 115.51 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Adult Prisons and Jails Reporting § 115.51 Inmate reporting. (a) The agency shall provide...

28 CFR 115.393 - Audits of standards.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Audits of standards. 115.393 Section 115.393 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Audits § 115.393 Audits of standards. The agency shall conduct...

28 CFR 115.193 - Audits of standards.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Audits of standards. 115.193 Section 115.193 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Audits § 115.193 Audits of standards. The agency shall conduct audits...

28 CFR 115.393 - Audits of standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Audits of standards. 115.393 Section 115.393 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Juvenile Facilities Audits § 115.393 Audits of standards. The agency shall conduct...

28 CFR 115.193 - Audits of standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Audits of standards. 115.193 Section 115.193 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Audits § 115.193 Audits of standards. The agency shall conduct audits...

28 CFR 115.172 - Evidentiary standard for administrative investigations.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Evidentiary standard for administrative investigations. 115.172 Section 115.172 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Standards for Lockups Investigations § 115.172 Evidentiary standard for...