Gene drive systems for insect disease vectors.
Sinkins, Steven P; Gould, Fred
2006-06-01
The elegant mechanisms by which naturally occurring selfish genetic elements, such as transposable elements, meiotic drive genes, homing endonuclease genes and Wolbachia, spread at the expense of their hosts provide some of the most fascinating and remarkable subjects in evolutionary genetics. These elements also have enormous untapped potential to be used in the control of some of the world's most devastating diseases. Effective gene drive systems for spreading genes that can block the transmission of insect-borne pathogens are much needed. Here we explore the potential of natural gene drive systems and discuss the artificial constructs that could be envisaged for this purpose.
Finite Element Analysis of Flexural Vibrations in Hard Disk Drive Spindle Systems
NASA Astrophysics Data System (ADS)
LIM, SEUNGCHUL
2000-06-01
This paper is concerned with the flexural vibration analysis of the hard disk drive (HDD) spindle system by means of the finite element method. In contrast to previous research, every system component is here analytically modelled taking into account its structural flexibility and also the centrifugal effect particularly on the disk. To prove the effectiveness and accuracy of the formulated models, commercial HDD systems with two and three identical disks are selected as examples. Then their major natural modes are computed with only a small number of element meshes as the shaft rotational speed is varied, and subsequently compared with the existing numerical results obtained using other methods and newly acquired experimental ones. Based on such a series of studies, the proposed method can be concluded as a very promising tool for the design of HDDs and various other high-performance computer disk drives such as floppy disk drives, CD ROM drives, and their variations having spindle mechanisms similar to those of HDDs.
Dynamic analysis and vibration testing of CFRP drive-line system used in heavy-duty machine tool
NASA Astrophysics Data System (ADS)
Yang, Mo; Gui, Lin; Hu, Yefa; Ding, Guoping; Song, Chunsheng
2018-03-01
Low critical rotary speed and large vibration in the metal drive-line system of heavy-duty machine tool affect the machining precision seriously. Replacing metal drive-line with the CFRP drive-line can effectively solve this problem. Based on the composite laminated theory and the transfer matrix method (TMM), this paper puts forward a modified TMM to analyze dynamic characteristics of CFRP drive-line system. With this modified TMM, the CFRP drive-line of a heavy vertical miller is analyzed. And the finite element modal analysis model of the shafting is established. The results of the modified TMM and finite element analysis (FEA) show that the modified TMM can effectively predict the critical rotary speed of CFRP drive-line. And the critical rotary speed of CFRP drive-line is 20% higher than that of the original metal drive-line. Then, the vibration of the CFRP and the metal drive-line were tested. The test results show that application of the CFRP drive shaft in the drive-line can effectively reduce the vibration of the heavy-duty machine tool.
Identification of germline transcriptional regulatory elements in Aedes aegypti.
Akbari, Omar S; Papathanos, Philippos A; Sandler, Jeremy E; Kennedy, Katie; Hay, Bruce A
2014-02-04
The mosquito Aedes aegypti is the principal vector for the yellow fever and dengue viruses, and is also responsible for recent outbreaks of the alphavirus chikungunya. Vector control strategies utilizing engineered gene drive systems are being developed as a means of replacing wild, pathogen transmitting mosquitoes with individuals refractory to disease transmission, or bringing about population suppression. Several of these systems, including Medea, UD(MEL), and site-specific nucleases, which can be used to drive genes into populations or bring about population suppression, utilize transcriptional regulatory elements that drive germline-specific expression. Here we report the identification of multiple regulatory elements able to drive gene expression specifically in the female germline, or in the male and female germline, in the mosquito Aedes aegypti. These elements can also be used as tools with which to probe the roles of specific genes in germline function and in the early embryo, through overexpression or RNA interference.
Identification of germline transcriptional regulatory elements in Aedes aegypti
NASA Astrophysics Data System (ADS)
Akbari, Omar S.; Papathanos, Philippos A.; Sandler, Jeremy E.; Kennedy, Katie; Hay, Bruce A.
2014-02-01
The mosquito Aedes aegypti is the principal vector for the yellow fever and dengue viruses, and is also responsible for recent outbreaks of the alphavirus chikungunya. Vector control strategies utilizing engineered gene drive systems are being developed as a means of replacing wild, pathogen transmitting mosquitoes with individuals refractory to disease transmission, or bringing about population suppression. Several of these systems, including Medea, UDMEL, and site-specific nucleases, which can be used to drive genes into populations or bring about population suppression, utilize transcriptional regulatory elements that drive germline-specific expression. Here we report the identification of multiple regulatory elements able to drive gene expression specifically in the female germline, or in the male and female germline, in the mosquito Aedes aegypti. These elements can also be used as tools with which to probe the roles of specific genes in germline function and in the early embryo, through overexpression or RNA interference.
Fuel pumping system and method
Shafer, Scott F [Morton, IL; Wang, Lifeng ,
2006-12-19
A fuel pumping system that includes a pump drive is provided. A first pumping element is operatively connected to the pump drive and is operable to generate a first flow of pressurized fuel. A second pumping element is operatively connected to the pump drive and is operable to generate a second flow of pressurized fuel. A first solenoid is operatively connected to the first pumping element and is operable to vary at least one of a fuel pressure and a fuel flow rate of the first flow of pressurized fuel. A second solenoid is operatively connected to the second pumping element and is operable to vary at least one of a fuel pressure and a fuel flow rate of the second flow of pressurized fuel.
Fuel Pumping System And Method
Shafer, Scott F.; Wang, Lifeng
2005-12-13
A fuel pumping system that includes a pump drive is provided. A first pumping element is operatively connected to the pump drive and is operable to generate a first flow of pressurized fuel. A second pumping element is operatively connected to the pump drive and is operable to generate a second flow of pressurized fuel. A first solenoid is operatively connected to the first pumping element and is operable to vary at least one of a fuel pressure and a fuel flow rate of the first flow of pressurized fuel. A second solenoid is operatively connected to the second pumping element and is operable to vary at least one of a fuel pressure and a fuel flow rate of the second flow of pressurized fuel.
Fjield, T; Hynynen, K
2000-01-01
Phased-array technology offers an incredible advantage to therapeutic ultrasound due to the ability to electronically steer foci, create multiple foci, or to create an enlarged focal region by using phase cancellation. However, to take advantage of this flexibility, the phased-arrays generally consist of many elements. Each of these elements requires its own radio-frequency generator with independent amplitude and phase control, resulting in a large, complex, and expensive driving system. A method is presented here where in certain cases the number of amplifier channels can be reduced to a fraction of the number of transducer elements, thereby simplifying the driving system and reducing the overall system complexity and cost, by using isolation transformers to produce 180 degrees phase shifts.
A vibroacoustic diagnostic system as an element improving road transport safety.
Komorska, Iwona
2013-01-01
Mechanical defects of a vehicle driving system can be dangerous on the road. Diagnostic systems, which monitor operations of electric and electronic elements and devices of vehicles, are continuously developed and improved, while defects of mechanical systems are still not managed properly. This article proposes supplementing existing on-board diagnostics with a system of diagnosing selected defects to minimize their impact. It presents a method of diagnosing mechanical defects of the engine, gearbox and other elements of the driving system on the basis of a model of the vibration signal obtained adaptively. This method is suitable for engine valves, engine head gasket, main gearbox, joints, etc.
Sensing mode atomic force microscope
Hough, Paul V. C.; Wang, Chengpu
2003-01-01
An atomic force microscope utilizes a pulse release system and improved method of operation to minimize contact forces between a probe tip affixed to a flexible cantilever and a specimen being measured. The pulse release system includes a magnetic particle affixed proximate the probe tip and an electromagnetic coil. When energized, the electromagnetic coil generates a magnetic field which applies a driving force on the magnetic particle sufficient to overcome adhesive forces exhibited between the probe tip and specimen. The atomic force microscope includes two independently displaceable piezo elements operable along a Z-axis. A controller drives the first Z-axis piezo element to provide a controlled approach between the probe tip and specimen up to a point of contact between the probe tip and specimen. The controller then drives the first Z-axis piezo element to withdraw the cantilever from the specimen. The controller also activates the pulse release system which drives the probe tip away from the specimen during withdrawal. Following withdrawal, the controller adjusts the height of the second Z-axis piezo element to maintain a substantially constant approach distance between successive samples.
NASA Technical Reports Server (NTRS)
Sinacori, J. B.
1980-01-01
A conceptual design of a visual system for a rotorcraft flight simulator is presented. Also, drive logic elements for a coupled motion base for such a simulator are given. The design is the result of an assessment of many potential arrangements of electro-optical elements and is a concept considered feasible for the application. The motion drive elements represent an example logic for a coupled motion base and is essentially an appeal to the designers of such logic to combine their washout and braking functions.
Electric drive systems including smoothing capacitor cooling devices and systems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dede, Ercan Mehmet; Zhou, Feng
An electric drive system includes a smoothing capacitor including at least one terminal, a bus bar electrically coupled to the at least one terminal, a thermoelectric device including a first side and a second side positioned opposite the first side, where the first side is thermally coupled to at least one of the at least one terminal and the bus bar, and a cooling element thermally coupled to the second side of the thermoelectric device, where the cooling element dissipates heat from the thermoelectric device.
DOT National Transportation Integrated Search
1978-01-01
A system analysis was completed of the general deterrence of driving while intoxicated (DWI). Elements which influence DWI decisions were identified and interrelated in a system model; then, potential countermeasures which might be employed in DWI ge...
AUTOMATIC FREQUENCY CONTROL SYSTEM
Hansen, C.F.; Salisbury, J.D.
1961-01-10
A control is described for automatically matching the frequency of a resonant cavity to that of a driving oscillator. The driving oscillator is disconnected from the cavity and a secondary oscillator is actuated in which the cavity is the frequency determining element. A low frequency is mixed with the output of the driving oscillator and the resultant lower and upper sidebands are separately derived. The frequencies of the sidebands are compared with the secondary oscillator frequency. deriving a servo control signal to adjust a tuning element in the cavity and matching the cavity frequency to that of the driving oscillator. The driving oscillator may then be connected to the cavity.
Management of scientific information with Google Drive.
Kubaszewski, Łukasz; Kaczmarczyk, Jacek; Nowakowski, Andrzej
2013-09-20
The amount and diversity of scientific publications requires a modern management system. By "management" we mean the process of gathering interesting information for the purpose of reading and archiving for quick access in future clinical practice and research activity. In the past, such system required physical existence of a library, either institutional or private. Nowadays in an era dominated by electronic information, it is natural to migrate entire systems to a digital form. In the following paper we describe the structure and functions of an individual electronic library system (IELiS) for the management of scientific publications based on the Google Drive service. Architecture of the system. Architecture system consists of a central element and peripheral devices. Central element of the system is virtual Google Drive provided by Google Inc. Physical elements of the system include: tablet with Android operating system and a personal computer, both with internet access. Required software includes a program to view and edit files in PDF format for mobile devices and another to synchronize the files. Functioning of the system. The first step in creating a system is collection of scientific papers in PDF format and their analysis. This step is performed most frequently on a tablet. At this stage, after being read, the papers are cataloged in a system of folders and subfolders, according to individual demands. During this stage, but not exclusively, the PDF files are annotated by the reader. This allows the user to quickly track down interesting information in review or research process. Modification of the document title is performed at this stage, as well. Second element of the system is creation of a mirror database in the Google Drive virtual memory. Modified and cataloged papers are synchronized with Google Drive. At this stage, a fully functional scientific information electronic library becomes available online. The third element of the system is a periodic two-way synchronization of data between Google Drive and tablet, as occasional modification of the files with annotation or recataloging may be performed at both locations. The system architecture is designed to gather, catalog and analyze scientific publications. All steps are electronic, eliminating paper forms. Indexed files are available for re-reading and modification. The system allows for fast access to full-text search with additional features making research easier. Team collaboration is also possible with full control of user privileges. Particularly important is the safety of collected data. In our opinion, the system exceeds many commercially available applications in terms of functionality and versatility.
The general deterrence of driving while intoxicated. Volume 2, Subsystem analyses
DOT National Transportation Integrated Search
1978-04-01
A system analysis was completed of the general deterrence of driving while intoxicated (DWI). Elements which influence DWI 'decisions were identified and interrelated in a system model; then, potential countermeasures which might be employed in DWI g...
Control of adaptive optic element displacement with the help of a magnetic rheology drive
NASA Astrophysics Data System (ADS)
Deulin, Eugeni A.; Mikhailov, Valeri P.; Sytchev, Victor V.
2000-10-01
The control system of adaptive optic of a large astronomical segmentated telescope was designed and tested. The dynamic model and the amplitude-frequency analysis of the new magnetic rheology (MR) drive are presented. The loop controlled drive consists of hydrostatic carrier, MR hydraulic loop controlling system, elastic thin wall seal, stainless seal which are united in a single three coordinate manipulator. This combination ensures short positioning error (delta) (phi)
Automatic Recognition and Understanding of the Driving Environment for Driver Feedback
DOT National Transportation Integrated Search
2018-01-01
A smart driving system must consider two key elements to be able to generate recommendations and make driving decisions that are effective and accurate: The environment of the car and the behavior of the driver. Our long-term goal is to develop techn...
Tilt assembly for tracking solar collector assembly
Almy, Charles; Peurach, John; Sandler, Reuben
2012-01-24
A tilt assembly is used with a solar collector assembly of the type comprising a frame, supporting a solar collector, for movement about a tilt axis by pivoting a drive element between first and second orientations. The tilt assembly comprises a drive element coupler connected to the drive element and a driver, the driver comprising a drive frame, a drive arm and a drive arm driver. The drive arm is mounted to the drive frame for pivotal movement about a drive arm axis. Movement on the drive arm mimics movement of the drive element. Drive element couplers can extend in opposite directions from the outer portion of the drive arm, whereby the assembly can be used between adjacent solar collector assemblies in a row of solar collector assemblies.
Design and implementation of scalable tape archiver
NASA Technical Reports Server (NTRS)
Nemoto, Toshihiro; Kitsuregawa, Masaru; Takagi, Mikio
1996-01-01
In order to reduce costs, computer manufacturers try to use commodity parts as much as possible. Mainframes using proprietary processors are being replaced by high performance RISC microprocessor-based workstations, which are further being replaced by the commodity microprocessor used in personal computers. Highly reliable disks for mainframes are also being replaced by disk arrays, which are complexes of disk drives. In this paper we try to clarify the feasibility of a large scale tertiary storage system composed of 8-mm tape archivers utilizing robotics. In the near future, the 8-mm tape archiver will be widely used and become a commodity part, since recent rapid growth of multimedia applications requires much larger storage than disk drives can provide. We designed a scalable tape archiver which connects as many 8-mm tape archivers (element archivers) as possible. In the scalable archiver, robotics can exchange a cassette tape between two adjacent element archivers mechanically. Thus, we can build a large scalable archiver inexpensively. In addition, a sophisticated migration mechanism distributes frequently accessed tapes (hot tapes) evenly among all of the element archivers, which improves the throughput considerably. Even with the failures of some tape drives, the system dynamically redistributes hot tapes to the other element archivers which have live tape drives. Several kinds of specially tailored huge archivers are on the market, however, the 8-mm tape scalable archiver could replace them. To maintain high performance in spite of high access locality when a large number of archivers are attached to the scalable archiver, it is necessary to scatter frequently accessed cassettes among the element archivers and to use the tape drives efficiently. For this purpose, we introduce two cassette migration algorithms, foreground migration and background migration. Background migration transfers cassettes between element archivers to redistribute frequently accessed cassettes, thus balancing the load of each archiver. Background migration occurs the robotics are idle. Both migration algorithms are based on access frequency and space utility of each element archiver. To normalize these parameters according to the number of drives in each element archiver, it is possible to maintain high performance even if some tape drives fail. We found that the foreground migration is efficient at reducing access response time. Beside the foreground migration, the background migration makes it possible to track the transition of spatial access locality quickly.
Chmátal, Lukáš; Schultz, Richard M; Black, Ben E; Lampson, Michael A
2017-01-01
Mendel's First Law of Genetics states that a pair of alleles segregates randomly during meiosis so that one copy of each is represented equally in gametes. Whereas male meiosis produces four equal sperm, in female meiosis only one cell, the egg, survives, and the others degenerate. Meiotic drive is a process in which a selfish DNA element exploits female meiotic asymmetry and segregates preferentially to the egg in violation of Mendel's First Law, thereby increasing its transmission to the offspring and frequency in a population. In principle, the selfish element can consist either of a centromere that increases its transmission via an altered kinetochore connection to the meiotic spindle or a centromere-like element that somehow bypasses the kinetochore altogether in doing so. There are now examples from eukaryotic model systems for both types of meiotic drive. Although meiotic drive has profound evolutionary consequences across many species, relatively little is known about the underlying mechanisms. We discuss examples in various systems and open questions about the underlying cell biology, and propose a mechanism to explain biased segregation in mammalian female meiosis.
Low-cost infrared glass for IR imaging applications
NASA Astrophysics Data System (ADS)
Graham, Amy G.; LeBlanc, Richard A.; Hilton, Ray A., Sr.
2003-09-01
With the advent of the uncooled detectors, the fraction of infrared (IR) imaging system cost due to lens elements has risen to the point where work was needed in the area of cost. Since these IR imaging systems often have tight packaging requirements which drive the optical elements to have complex surfaces, typical IR optical elements are costly to manufacture. The drive of our current optical material research is to lower the cost of the materials as well as the element fabrication for IR imaging systems. A low cost, moldable amorphous material, Amtir-4, has been developed and characterized. Ray Hilton Sr., Amorphous Materials Inc., Richard A. LeBlanc, Amy Graham and Others at Lockheed Martin Missiles and Fire Control Orlando (LMMFC-O) and James Johnson, General Electric Global Research Center (GE-GRC), along with others have been doing research for the past three years characterizing and designing IR imaging systems with this material. These IR imaging systems have been conventionally fabricated via diamond turning and techniques required to mold infrared optical elements have been developed with this new material, greatly reducing manufacturing costs. This paper will outline efforts thus far in incorporating this new material into prototype IR imaging systems.
A novel phase assignment protocol and driving system for a high-density focused ultrasound array.
Caulfield, R Erich; Yin, Xiangtao; Juste, Jose; Hynynen, Kullervo
2007-04-01
Currently, most phased-array systems intended for therapy are one-dimensional (1-D) and use between 5 and 200 elements, with a few two-dimensional (2-D) systems using several hundred elements. The move toward lambda/2 interelement spacing, which provides complete 3-D beam steering, would require a large number of closely spaced elements (0.15 mm to 3 mm). A solution to the resulting problem of cost and cable assembly size, which this study examines, is to quantize the phases available at the array input. By connecting elements with similar phases to a single wire, a significant reduction in the number of incoming lines can be achieved while maintaining focusing and beam steering capability. This study has explored the feasibility of such an approach using computer simulations and experiments with a test circuit driving a 100-element linear array. Simulation results demonstrated that adequate focusing can be obtained with only four phase signals without large increases in the grating lobes or the dimensions of the focus. Experiments showed that the method can be implemented in practice, and adequate focusing can be achieved with four phase signals with a reduction of 20% in the peak pressure amplitude squared when compared with the infinite-phase resolution case. Results indicate that the use of this technique would make it possible to drive more than 10,000 elements with 33 input lines. The implementation of this method could have a large impact on ultrasound therapy and diagnostic devices.
NASA Astrophysics Data System (ADS)
Ganghoffer, J. F.; Boubaker, M. B.
2017-03-01
We adopt in this paper the physically and micromechanically motivated point of view that growth (resp. resorption) occurs as the expansion (resp. contraction) of initially small tissue elements distributed within a host surrounding matrix, due to the interfacial motion of their boundary. The interface motion is controlled by the availability of nutrients and mechanical driving forces resulting from the internal stresses that built in during the growth. A general extremum principle of the zero potential for open systems witnessing a change of their mass due to the diffusion of nutrients is constructed, considering the framework of open systems thermodynamics. We postulate that the shape of the tissue element evolves in such a way as to minimize the zero potential among all possible admissible shapes of the growing tissue elements. The resulting driving force for the motion of the interface sets a surface growth models at the scale of the growing tissue elements, and is conjugated to a driving force identified as the interfacial jump of the normal component of an energy momentum tensor, in line with Hadamard's structure theorem. The balance laws associated with volumetric growth at the mesoscopic level result as the averaging of surface growth mechanisms occurring at the microscopic scale of the growing tissue elements. The average kinematics has been formulated in terms of the effective growth velocity gradient and elastic rate of deformation tensor, both functions of time. This formalism is exemplified by the simulation of the avascular growth of multicell spheroids in the presence of diffusion of nutrients, showing the respective influence of mechanical and chemical driving forces in relation to generation of internal stresses.
Simplified fatigue life analysis for traction drive contacts
NASA Technical Reports Server (NTRS)
Rohn, D. A.; Loewenthal, S. H.; Coy, J. J.
1980-01-01
A simplified fatigue life analysis for traction drive contacts of arbitrary geometry is presented. The analysis is based on the Lundberg-Palmgren theory used for rolling-element bearings. The effects of torque, element size, speed, contact ellipse ratio, and the influence of traction coefficient are shown. The analysis shows that within the limits of the available traction coefficient, traction contacts exhibit longest life at high speeds. Multiple, load-sharing roller arrangements have an advantageous effect on system life, torque capacity, power-to-weight ratio and size.
Banks, Victoria A; Stanton, Neville A; Harvey, Catherine
2014-01-01
Although task analysis of pedestrian detection can provide us with useful insights into how a driver may behave in emergency situations, the cognitive elements of driver decision-making are less well understood. To assist in the design of future Advanced Driver Assistance Systems, such as Autonomous Emergency Brake systems, it is essential that the cognitive elements of the driving task are better understood. This paper uses verbal protocol analysis in an exploratory fashion to uncover the thought processes underlying behavioural outcomes represented by hard data collected using the Southampton University Driving Simulator.
Effectiveness of graduated driver licensing in reducing motor vehicle crashes.
Foss, R D; Evenson, K R
1999-01-01
To determine whether graduated driver licensing (GDL) systems and nighttime curfews reduce motor vehicle crashes, fatalities, or injuries among young drivers. We used Cochrane Collaboration search strategies to locate studies of graduated licensing or night driving restrictions. Studies were selected if they examined the effects of either (1) a comprehensive graduated driver licensing system including well-integrated components, or (2) nighttime driving restrictions/curfews that could affect young persons' nighttime driving, on a clearly defined crash or injury outcome. Seven studies met inclusion criteria. Two independent studies of the New Zealand graduated licensing program found a sustained 7%-8% reduction in teen driver crash injuries attributable to the program. No other full graduated licensing system has been evaluated to date. Four studies of either a general curfew or a nighttime driving restriction for teens, a key element of graduated licensing, found substantial crash reductions during restricted hours, with 23%-25% lower crash injury and fatality rates for curfews beginning prior to midnight. One study found no change in late night crashes before and after a 1 a.m.-6 a.m. night driving restriction took effect. The logic and empirical bases for graduated licensing are sound. Moreover, there is evidence that one central element, a restriction on nighttime driving by novices, reduces young driver crashes. However, a definitive conclusion about the effectiveness of GDL systems for reducing motor vehicle crashes or crash-related injuries must await examination of other GDL systems. This should be possible within the next few years, as several states and Canadian provinces have recently enacted GDL programs.
Automatic inoculating apparatus. [includes movable carraige, drive motor, and swabbing motor
NASA Technical Reports Server (NTRS)
Wilkins, J. R.; Mills, S. M. (Inventor)
1974-01-01
An automatic inoculating apparatus for agar trays is described and using a simple inoculating element, such as a cotton swab or inoculating loop. The apparatus includes a movable carriage for supporting the tray to be inoculated, a drive motor for moving the tray along a trackway, and a swabbing motor for automatically swabbing the tray during the movement. An actuator motor controls lowering of the inoculating element onto the tray and lifting of the inoculating element. An electrical control system, including limit microswitches, enables automatic control of the actuator motor and return of the carriage to the initial position after inoculating is completed.
NASA Astrophysics Data System (ADS)
Leukhin, R. I.; Shaykhutdinov, D. V.; Shirokov, K. M.; Narakidze, N. D.; Vlasov, A. S.
2017-02-01
Developing the experimental design of new electromagnetic constructions types in engineering industry enterprises requires solutions of two major problems: regulator’s parameters setup and comprehensive testing of electromagnets. A weber-ampere characteristic as a data source for electromagnet condition identification was selected. Present article focuses on development and implementation of the software for electromagnetic drive control system based on the weber-ampere characteristic measuring. The software for weber-ampere characteristic data processing based on artificial neural network is developed. Results of the design have been integrated into the program code in LabVIEW environment. The license package of LabVIEW graphic programming was used. The hardware is chosen and possibility of its use for control system implementation was proved. The trained artificial neural network defines electromagnetic drive effector position with minimal error. Developed system allows to control the electromagnetic drive powered by the voltage source, the current source and hybrid sources.
SEX-RATIO MEIOTIC DRIVE AND INTERSPECIFIC COMPETITION
Unckless, Robert L.; Clark, Andrew G.
2014-01-01
It has long been known that processes occurring within a species may impact the interactions between species. For example, since competitive ability is sensitive to parameters including reproductive rate, carrying capacity and competition efficiency, the outcome of interspecific competition may be influenced by any process that alters these attributes. While several such scenarios have been discussed, the influence of selfish genetic elements within one species on competition between species has not received theoretical treatment. We show that, with strong competition, sex-ratio meiotic drive systems can result in a significant shift in community composition because the effective birth rate in the population may be increased by a female-biased sex-ratio. Using empirical data we attempt to estimate the magnitude of this effect in several Drosophila species. We infer that meiotic drive elements, selfish genetic elements within species, can provide a substantial competitive advantage to that species within a community. PMID:24835887
A drive based on an element made of a thermomechanical memory material
NASA Astrophysics Data System (ADS)
Krakhin, O. I.; Dubovik, I. N.; Rozarenova, Iu. A.
The advantages of using drives with active elements made of thermomechanical memory materials in aircraft structures are briefly reviewed. The choice of a particular type of active element based on a thermomechanical memory material is shown to depend on the specific operating conditions of the drive. The design of a rotary drive with an active element of TN-1 alloy is examined as an example.
NASA Astrophysics Data System (ADS)
Tcherdyntsev, V. V.; Kaloshkin, S. D.; Shelekhov, E. V.; Principi, G.; Rodin, A. O.
2008-02-01
Al65Cu23Fe12 alloys were prepared by ball milling of the elemental powders mixture. Phase and structural transformations at heating of as-milled powders were investigated by X-ray diffraction analysis. Precision analysis of Mössbauer spectra was performed to check the adequacy of the fitting of X-ray diffraction patterns. The results were compared with the data of differential scanning and solution calorimetry, as well as with the thermodynamic literature data, in order to estimate the driving forces of redistribution of elements that preceded the formation of single-phase quasicrystalline structure. The heat of elements mixing, which is positive for Cu-Fe system and negative for Al-Fe and Al-Cu systems, was supposed to be a decisive factor for phase transformations during heating of the alloy. The correlation between sequence of phase transformations during heating and the thermodynamic data was discussed and the scheme describing phase transformations observed was proposed.
Finite element based electric motor design optimization
NASA Technical Reports Server (NTRS)
Campbell, C. Warren
1993-01-01
The purpose of this effort was to develop a finite element code for the analysis and design of permanent magnet electric motors. These motors would drive electromechanical actuators in advanced rocket engines. The actuators would control fuel valves and thrust vector control systems. Refurbishing the hydraulic systems of the Space Shuttle after each flight is costly and time consuming. Electromechanical actuators could replace hydraulics, improve system reliability, and reduce down time.
Background and system description of the Mod 1 wind turbine generator
NASA Technical Reports Server (NTRS)
Ernst, E. H.
1978-01-01
The Mod-1 wind turbine considered is a large utility-class machine, operating in the high wind regime, which has the potential for generation of utility grade power at costs competitive with other alternative energy sources. A Mod-1 wind turbine generator (WTG) description is presented, taking into account the two variable-pitch steel blades of the rotor, the drive train, power generation/control, the Nacelle structure, and the yaw drive. The major surface elements of the WTG are the ground enclosure, the back-up battery system, the step-up transformer, elements of the data system, cabling, area lighting, and tower foundation. The final system weight (rotor, Nacelle, and tower) is expected to be about 650,000 pounds. The WTG will be capable of delivering 1800 kW to the utility grid in a wind-speed above 25 mph.
Optimization of Smart Structure for Improving Servo Performance of Hard Disk Drive
NASA Astrophysics Data System (ADS)
Kajiwara, Itsuro; Takahashi, Masafumi; Arisaka, Toshihiro
Head positioning accuracy of the hard disk drive should be improved to meet today's increasing performance demands. Vibration suppression of the arm in the hard disk drive is very important to enhance the servo bandwidth of the head positioning system. In this study, smart structure technology is introduced into the hard disk drive to suppress the vibration of the head actuator. It has been expected that the smart structure technology will contribute to the development of small and light-weight mechatronics devices with the required performance. First, modeling of the system is conducted with finite element method and modal analysis. Next, the actuator location and the control system are simultaneously optimized using genetic algorithm. Vibration control effect with the proposed vibration control mechanisms has been evaluated by some simulations.
Investigation of control system of traction electric drive with feedbacks on load
NASA Astrophysics Data System (ADS)
Kuznetsov, N. K.; Iov, I. A.; Iov, A. A.
2018-03-01
In the article, by the example of a walking excavator, the results of a study of a control system of traction electric drive with a rigid and flexible feedback on the load are mentioned. Based on the analysis of known works, the calculation scheme has been chosen; the equations of motion of the electromechanical system have been obtained, taking into account the elasticity of the rope and feedbacks on the load in the elastic element. A simulation model of this system has been developed and mathematical modeling of the transient processes to evaluate the influence of feedback on the dynamic characteristics of the mechanism and its efficiency of work was carried out. It is shown that the use of rigid and flexible feedbacks makes it possible to reduce dynamic loads in the traction mechanism and to limit the elastic oscillation of the executive mechanism in transient operating modes in comparison with the standard control system; however, there is some decrease in productivity. It has been also established that the sign-variable of the loading of the electric drive, connected with the opening of the backlashes in the gearbox due to the action of feedbacks on the load in the elastic element, under certain conditions, can lead to undesirable phenomena in the operation of the drive and a decrease in the reliability of its operation.
A Uniform Approach to National Suicide Bomber Incident Response and Recovery
2008-03-01
33 D. ELEMENTS OF MOTIVATION.................................................................35 E. THE TAMIL TIGER INFLUENCE...34 Ibid., 11. 35 Ibid., 8-12. 12 support of common objectives. Use of the Incident Command System (ICS) is an important element across multi... elements : • Initial strategic focus: to drive overt and covert United States forces from Muslim lands in the Near and Middle East. Covert American
Conditions for success of engineered underdominance gene drive systems.
Edgington, Matthew P; Alphey, Luke S
2017-10-07
Engineered underdominance is one of a number of different gene drive strategies that have been proposed for the genetic control of insect vectors of disease. Here we model a two-locus engineered underdominance based gene drive system that is based on the concept of mutually suppressing lethals. In such a system two genetic constructs are introduced, each possessing a lethal element and a suppressor of the lethal at the other locus. Specifically, we formulate and analyse a population genetics model of this system to assess when different combinations of release strategies (i.e. single or multiple releases of both sexes or males only) and genetic systems (i.e. bisex lethal or female-specific lethal elements and different strengths of suppressors) will give population replacement or fail to do so. We anticipate that results presented here will inform the future design of engineered underdominance gene drive systems as well as providing a point of reference regarding release strategies for those looking to test such a system. Our discussion is framed in the context of genetic control of insect vectors of disease. One of several serious threats in this context are Aedes aegypti mosquitoes as they are the primary vectors of dengue viruses. However, results are also applicable to Ae. aegypti as vectors of Zika, yellow fever and chikungunya viruses and also to the control of a number of other insect species and thereby of insect-vectored pathogens. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.
Chen, Chun-Hong; Ward, Catherine M.; Huang, Haixia; Su, Jessica T.; Guo, Ming
2013-01-01
Advances in insect transgenesis and our knowledge of insect physiology and genomics are making it possible to create transgenic populations of beneficial or pest insects that express novel traits. There are contexts in which we may want the transgenes responsible for these traits to spread so that all individuals within a wild population carry them, a process known as population replacement. Transgenes of interest are unlikely to confer an overall fitness benefit on those who carry them. Therefore, an essential component of any population replacement strategy is the presence of a drive mechanism that will ensure the spread of linked transgenes. We discuss contexts in which population replacement might be desirable and the requirements a drive system must satisfy to be both effective and safe. We then describe the creation of synthetic Medea elements, the first selfish genetic elements synthesized de novo, with the capability of driving population replacement, in this case in Drosophila. The strategy used to create Drosophila Medea is applicable to a number of other insect species and the Medea system satisfies key requirements for scientific and social acceptance. Finally, we highlight several challenges to implementing population replacement in the wild. PMID:20570677
Friction self-oscillation decrease in nonlinear system of locomotive traction drive
NASA Astrophysics Data System (ADS)
Antipin, D. Ya; Vorobiyov, V. I.; Izmerov, O. V.; Shorokhov, S. G.; Bondarenko, D. A.
2017-02-01
The problems of the friction self-oscillation decrease in a nonlinear system of a locomotive traction drive are considered. It is determined that the self-oscillation amplitude decrease in a locomotive wheel pair during boxing in traction drives with an elastic linkage between an armature of a traction electric motor and gearing can be achieved due to drive damping capacity during impact vibro-damping in an axle reduction gear with a hard driven gear. The self-oscillation amplitude reduction in a wheel pair in the designs of locomotive traction drives with the location of elastic elements between a wheel pair and gearing can be obtained owing to the application of drive inertial masses as an anti-vibrator. On the basis of the carried out investigations, a design variant of a self-oscillation shock absorber of a traction electric motor framework on a reduction gear suspension with an absorber located beyond a wheel-motor unit was offered.
Study on development system of increasing gearbox for high-performance wind-power generator
NASA Astrophysics Data System (ADS)
Xu, Hongbin; Yan, Kejun; Zhao, Junyu
2005-12-01
Based on the analysis of the development potentiality of wind-power generator and domestic manufacture of its key parts in China, an independent development system of the Increasing Gearbox for High-performance Wind-power Generator (IGHPWG) was introduced. The main elements of the system were studied, including the procedure design, design analysis system, manufacturing technology and detecting system, and the relative important technologies were analyzed such as mixed optimal joint transmission structure of the first planetary drive with two grade parallel axle drive based on equal strength, tooth root round cutting technology before milling hard tooth surface, high-precise tooth grinding technology, heat treatment optimal technology and complex surface technique, and rig test and detection technique of IGHPWG. The development conception was advanced the data share and quality assurance system through all the elements of the development system. The increasing Gearboxes for 600KW and 1MW Wind-power Generator have been successfully developed through the application of the development system.
Modelling and control algorithms of the cross conveyors line with multiengine variable speed drives
NASA Astrophysics Data System (ADS)
Cheremushkina, M. S.; Baburin, S. V.
2017-02-01
The paper deals with the actual problem of developing the control algorithm that meets the technical requirements of the mine belt conveyors, and enables energy and resource savings taking into account a random sort of traffic. The most effective method of solution of these tasks is the construction of control systems with the use of variable speed drives for asynchronous motors. The authors designed the mathematical model of the system ‘variable speed multiengine drive - conveyor - control system of conveyors’ that takes into account the dynamic processes occurring in the elements of the transport system, provides an assessment of the energy efficiency of application the developed algorithms, which allows one to reduce the dynamic overload in the belt to 15-20%.
Brand, Cara L; Larracuente, Amanda M; Presgraves, Daven C
2015-05-01
Meiotic drive elements are a special class of evolutionarily "selfish genes" that subvert Mendelian segregation to gain preferential transmission at the expense of homologous loci. Many drive elements appear to be maintained in populations as stable polymorphisms, their equilibrium frequencies determined by the balance between drive (increasing frequency) and selection (decreasing frequency). Here we show that a classic, seemingly balanced, drive system is instead characterized by frequent evolutionary turnover giving rise to dynamic, rather than stable, equilibrium frequencies. The autosomal Segregation Distorter (SD) system of the fruit fly Drosophila melanogaster is a selfish coadapted meiotic drive gene complex in which the major driver corresponds to a partial duplication of the gene Ran-GTPase activating protein (RanGAP). SD chromosomes segregate at similar, low frequencies of 1-5% in natural populations worldwide, consistent with a balanced polymorphism. Surprisingly, our population genetic analyses reveal evidence for parallel, independent selective sweeps of different SD chromosomes in populations on different continents. These findings suggest that, rather than persisting at a single stable equilibrium, SD chromosomes turn over frequently within populations. © 2015 The Author(s). Evolution published by Wiley Periodicals, Inc. on behalf of The Society for the Study of Evolution.
Sequenced drive for rotary valves
Mittell, Larry C.
1981-01-01
A sequenced drive for rotary valves which provides the benefits of applying rotary and linear motions to the movable sealing element of the valve. The sequenced drive provides a close approximation of linear motion while engaging or disengaging the movable element with the seat minimizing wear and damage due to scrubbing action. The rotary motion of the drive swings the movable element out of the flowpath thus eliminating obstruction to flow through the valve.
Visions of the Future: Hybrid Electric Aircraft Propulsion
NASA Technical Reports Server (NTRS)
Bowman, Cheryl L.
2016-01-01
The National Aeronautics and Space Administration (NASA) is investing continually in improving civil aviation. Hybridization of aircraft propulsion is one aspect of a technology suite which will transform future aircraft. In this context, hybrid propulsion is considered a combination of traditional gas turbine propulsion and electric drive enabled propulsion. This technology suite includes elements of propulsion and airframe integration, parallel hybrid shaft power, turbo-electric generation, electric drive systems, component development, materials development and system integration at multiple levels.
NASA Technical Reports Server (NTRS)
Juday, Richard D. (Inventor)
1998-01-01
An apparatus is disclosed for reading and/or writing information or to from an optical recording medium having a plurality of information storage layers. The apparatus includes a dynamic holographic optical element configured to focus light on the optical recording medium. a control circuit arranged to supply a drive signal to the holographic optical element, and a storage device in communication with the control circuit and storing at least a first drive signal and a second drive signal. The holographic optical element focusses light on a first one of the plurality of information storage layers when driven by the first drive signal on a second one of the plurality of information storage layers when driven by the second drive signal. An optical switch is also disclosed for connecting at least one light source in a source array to at least one light receiver in a receiver array. The switch includes a dynamic holographic optical element configured to receive light from the source array and to transmit light to the receiver array, a control circuit arranged to supply a drive signal to the holographic optical element, and a storage device in communication with the control circuit and storing at least a first drive signal and a second drive signal. The holographic optical element connects a first light source in the source array to a first light receiver in the receiver array when driven by the first drive signal and the holographic optical element connects the first light source with the first light receiver and a second light receiver when driven by the second drive signal.
NASA helicopter transmission system technology program
NASA Technical Reports Server (NTRS)
Zaretsky, E. V.
1983-01-01
The purpose of the NASA Helicopter Transmission System Technology Program is to improve specific mechanical components and the technology for combining these into advanced drive systems to make helicopters more viable and cost competitive for commerical applications. The history, goals, and elements of the program are discussed.
NASA Astrophysics Data System (ADS)
Kuznetsov, N. K.; Iov, I. A.; Iov, A. A.
2018-05-01
The article presents the results of a study of the efficiency of the electric drive control system of the traction mechanism of a dragline based on the use of feedback on load in the traction cable. The investigations were carried out using a refined electromechanical model of the traction mechanism, which took into account not only the elastic elements of the gearbox, the backlashes in it and the changes in the kinematic parameters of the mechanism during operation, but also the mechanical characteristics of the electric drive and the features of its control system. By mathematical modeling of the transient processes of the electromechanical system, it is shown that the introduction of feedback on the load in the elastic element allows one to reduce the dynamic loads in the traction mechanism and to limit the elastic oscillations of the actuating mechanism in comparison with the standard control system. Fixed as a general decrease in the dynamic load of the nodes of traction mechanism in the modes of loading and latching of the bucket, and a decrease the operating time of the mechanism at maximum load. At the same time, undesirable phenomena in the operation of the electric drive were also associated with the increase in the recovery time of the steady-state value of the speed of the actuating mechanism under certain operating conditions, which can lead to a decrease in the reliability of the mechanical part and the productivity of the traction mechanism.
Crack Driving Forces in a Multilayered Coating System for Ceramic Matrix Composite Substrates
NASA Technical Reports Server (NTRS)
Ghosn, Louis J.; Zhu, Dongming; Miller, Robert A.
2005-01-01
The effects of the top coating thickness, modulus and shrinkage strains on the crack driving forces for a baseline multilayer Yttria-Stabilized-Zirconia/Mullite/Si thermal and environment barrier coating (TEBC) system for SiC/SiC ceramic matrix composite substrates are determined for gas turbine applications. The crack driving forces increase with increasing modulus, and a low modulus thermal barrier coating material (below 10 GPa) will have no cracking issues under the thermal gradient condition analyzed. Since top coating sintering increases the crack driving forces with time, highly sintering resistant coatings are desirable to maintain a low tensile modulus and maintain a low crack driving force with time. Finite element results demonstrated that an advanced TEBC system, such as ZrO2/HfO2, which possesses improved sintering resistance and high temperature stability, exhibited excellent durability. A multi-vertical cracked structure with fine columnar spacing is an ideal strain tolerant coating capable of reducing the crack driving forces to an acceptable level even with a high modulus of 50 GPa.
The impact of dissociation on transposon-mediated disease control strategies.
Marshall, John M
2008-03-01
Vector-borne diseases such as malaria and dengue fever continue to be a major health concern through much of the world. The emergence of chloroquine-resistant strains of malaria and insecticide-resistant mosquitoes emphasize the need for novel methods of disease control. Recently, there has been much interest in the use of transposable elements to drive resistance genes into vector populations as a means of disease control. One concern that must be addressed before a release is performed is the potential loss of linkage between a transposable element and a resistance gene. Transposable elements such as P and hobo have been shown to produce internal deletion derivatives at a significant rate, and there is concern that a similar process could lead to loss of the resistance gene from the drive system following a transgenic release. Additionally, transposable elements such as Himar1 have been shown to transpose significantly more frequently when free of exogenous DNA. Here, we show that any transposon-mediated gene drive strategy must have an exceptionally low rate of dissociation if it is to be effective. Additionally, the resistance gene must confer a large selective advantage to the vector to surmount the effects of a moderate dissociation rate and transpositional handicap.
Simulating the dynamic behavior of chain drive systems by advanced CAE programs
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ross, J.; Meyer, J.
1996-09-01
Due to the increased requirements for chain drive systems of 4-stroke internal combustion engines CAE-tools are necessary to design the optimum dynamic system. In comparison to models used din the past the advantage of the new model CDD (Chain Drive Dynamics) is the capability of simulating the trajectory of each chain link around the drive system. Each chain link is represented by a mass with two degrees of freedom and is coupled to the next by a spring-damper element. The drive sprocket can be moved with a constant or non-constant speed. As in reality the other sprockets are driven bymore » the running chain and can be excited by torques. Due to these unique model features it is possible to calculate all vibration types of the chain, polygon effects and radial or angular vibrations of the sprockets very accurately. The model includes the detailed simulation of a mechanical or a hydraulic tensioner as well. The method is ready to be coupled to other detailed calculation models (e.g. valve train systems, crankshaft, etc.). The high efficiency of the tool predicting the dynamic and acoustic behavior of a chain drive system will be demonstrated in comparison to measurements.« less
Hay, Bruce A; Chen, Chun-Hong; Ward, Catherine M; Huang, Haixia; Su, Jessica T; Guo, Ming
2010-10-01
Advances in insect transgenesis and our knowledge of insect physiology and genomics are making it possible to create transgenic populations of beneficial or pest insects that express novel traits. There are contexts in which we may want the transgenes responsible for these traits to spread so that all individuals within a wild population carry them, a process known as population replacement. Transgenes of interest are unlikely to confer an overall fitness benefit on those who carry them. Therefore, an essential component of any population replacement strategy is the presence of a drive mechanism that will ensure the spread of linked transgenes. We discuss contexts in which population replacement might be desirable and the requirements a drive system must satisfy to be both effective and safe. We then describe the creation of synthetic Medea elements, the first selfish genetic elements synthesized de novo, with the capability of driving population replacement, in this case in Drosophila. The strategy used to create Drosophila Medea is applicable to a number of other insect species and the Medea system satisfies key requirements for scientific and social acceptance. Finally, we highlight several challenges to implementing population replacement in the wild. Copyright 2010 Elsevier Ltd. All rights reserved.
Laser Schlieren and ultraviolet diagnostics of rocket combustion
NASA Technical Reports Server (NTRS)
Fisher, S. C.
1985-01-01
A low pressure oxygen/hydrogen turbine drive combustor hot-fire test series was conducted on the Turbine Drive Combustor Technology Program. The first objective was to gather data on an axisymmetric combustion system to support anchoring of a new combustion/fluid dynamics computer code under development on the same contract. The second objective was to gain insight into low mixture ratio combustion characteristics of coaxial injector elements.
Akbari, Omar S; Chen, Chun-Hong; Marshall, John M; Huang, Haixia; Antoshechkin, Igor; Hay, Bruce A
2014-12-19
Insects act as vectors for diseases of plants, animals, and humans. Replacement of wild insect populations with genetically modified individuals unable to transmit disease provides a potentially self-perpetuating method of disease prevention. Population replacement requires a gene drive mechanism in order to spread linked genes mediating disease refractoriness through wild populations. We previously reported the creation of synthetic Medea selfish genetic elements able to drive population replacement in Drosophila. These elements use microRNA-mediated silencing of myd88, a maternally expressed gene required for embryonic dorso-ventral pattern formation, coupled with early zygotic expression of a rescuing transgene, to bring about gene drive. Medea elements that work through additional mechanisms are needed in order to be able to carry out cycles of population replacement and/or remove existing transgenes from the population, using second-generation elements that spread while driving first-generation elements out of the population. Here we report the synthesis and population genetic behavior of two new synthetic Medea elements that drive population replacement through manipulation of signaling pathways involved in cellular blastoderm formation or Notch signaling, demonstrating that in Drosophila Medea elements can be generated through manipulation of diverse signaling pathways. We also describe the mRNA and small RNA changes in ovaries and early embryos associated from Medea-bearing females. Finally, we use modeling to illustrate how Medea elements carrying genes that result in diapause-dependent female lethality could be used to bring about population suppression.
DNA transposon-based gene vehicles - scenes from an evolutionary drive
2013-01-01
DNA transposons are primitive genetic elements which have colonized living organisms from plants to bacteria and mammals. Through evolution such parasitic elements have shaped their host genomes by replicating and relocating between chromosomal loci in processes catalyzed by the transposase proteins encoded by the elements themselves. DNA transposable elements are constantly adapting to life in the genome, and self-suppressive regulation as well as defensive host mechanisms may assist in buffering ‘cut-and-paste’ DNA mobilization until accumulating mutations will eventually restrict events of transposition. With the reconstructed Sleeping Beauty DNA transposon as a powerful engine, a growing list of transposable elements with activity in human cells have moved into biomedical experimentation and preclinical therapy as versatile vehicles for delivery and genomic insertion of transgenes. In this review, we aim to link the mechanisms that drive transposon evolution with the realities and potential challenges we are facing when adapting DNA transposons for gene transfer. We argue that DNA transposon-derived vectors may carry inherent, and potentially limiting, traits of their mother elements. By understanding in detail the evolutionary journey of transposons, from host colonization to element multiplication and inactivation, we may better exploit the potential of distinct transposable elements. Hence, parallel efforts to investigate and develop distinct, but potent, transposon-based vector systems will benefit the broad applications of gene transfer. Insight and clever optimization have shaped new DNA transposon vectors, which recently debuted in the first DNA transposon-based clinical trial. Learning from an evolutionary drive may help us create gene vehicles that are safer, more efficient, and less prone for suppression and inactivation. PMID:24320156
Base drive circuit for a four-terminal power Darlington
Lee, Fred C.; Carter, Roy A.
1983-01-01
A high power switching circuit which utilizes a four-terminal Darlington transistor block to improve switching speed, particularly in rapid turn-off. Two independent reverse drive currents are utilized during turn off in order to expel the minority carriers of the Darlington pair at their own charge sweep-out rate. The reverse drive current may be provided by a current transformer, the secondary of which is tapped to the base terminal of the power stage of the Darlington block. In one application, the switching circuit is used in each power switching element in a chopper-inverter drive of an electric vehicle propulsion system.
Multiple-degree-of-freedom vehicle
Borenstein, Johann
1995-01-01
A multi-degree-of-freedom vehicle employs a compliant linkage to accommodate the need for a variation in the distance between drive wheels or drive systems which are independently steerable and drivable. The subject vehicle is provided with rotary encodes to provide signals representative of the orientation of the steering pivot associated with each such drive wheel or system, and a linear encoder which issues a signal representative of the fluctuations in the distance between the drive elements. The wheels of the vehicle are steered and driven in response to the linear encoder signal, there being provided a controller system for minimizing the fluctuations in the distance. The controller system is a software implementation of a plurality of controllers, operating at the chassis level and at the vehicle level. A trajectory interpolator receives x-displacement, y-displacement, and .theta.-displacement signals and produces to the vehicle level controller trajectory signals corresponding to interpolated control signals. The x-displacement, y-displacement, and .theta.-displacement signals are received from a human operator, via a manipulable joy stick.
The successful of finite element to invent particle cleaning system by air jet in hard disk drive
NASA Astrophysics Data System (ADS)
Jai-Ngam, Nualpun; Tangchaichit, Kaitfa
2018-02-01
Hard Disk Drive manufacturing has faced very challenging with the increasing demand of high capacity drives for Cloud-based storage. Particle adhesion has also become increasingly important in HDD to gain more reliability of storage capacity. The ability to clean on surfaces is more complicated in removing such particles without damaging the surface. This research is aim to improve the particle cleaning in HSA by using finite element to develop the air flow model then invent the prototype of air cleaning system to remove particle from surface. Surface cleaning by air pressure can be applied as alternative for the removal of solid particulate contaminants that is adhering on a solid surface. These technical and economic challenges have driven the process development from traditional way that chemical solvent cleaning. The focus of this study is to develop alternative way from scrub, ultrasonic, mega sonic on surface cleaning principles to serve as a foundation for the development of new processes to meet current state-of-the-art process requirements and minimize the waste from chemical cleaning for environment safety.
A synthetic maternal-effect selfish genetic element drives population replacement in Drosophila.
Chen, Chun-Hong; Huang, Haixia; Ward, Catherine M; Su, Jessica T; Schaeffer, Lorian V; Guo, Ming; Hay, Bruce A
2007-04-27
One proposed strategy for controlling the transmission of insect-borne pathogens uses a drive mechanism to ensure the rapid spread of transgenes conferring disease refractoriness throughout wild populations. Here, we report the creation of maternal-effect selfish genetic elements in Drosophila that drive population replacement and are resistant to recombination-mediated dissociation of drive and disease refractoriness functions. These selfish elements use microRNA-mediated silencing of a maternally expressed gene essential for embryogenesis, which is coupled with early zygotic expression of a rescuing transgene.
Maranhão, Geraldo Neves De A; Brito, Alaan Ubaiara; Leal, Anderson Marques; Fonseca, Jéssica Kelly Silva; Macêdo, Wilson Negrão
2015-09-22
In the present paper, a fuzzy controller applied to a Variable-Speed Drive (VSD) for use in Photovoltaic Pumping Systems (PVPS) is proposed. The fuzzy logic system (FLS) used is embedded in a microcontroller and corresponds to a proportional-derivative controller. A Light-Dependent Resistor (LDR) is used to measure, approximately, the irradiance incident on the PV array. Experimental tests are executed using an Arduino board. The experimental results show that the fuzzy controller is capable of operating the system continuously throughout the day and controlling the direct current (DC) voltage level in the VSD with a good performance.
Developments in the design, analysis, and fabrication of advanced technology transmission elements
NASA Technical Reports Server (NTRS)
Drago, R. J.; Lenski, J. W., Jr.
1982-01-01
Over the last decade, the presently reported proprietary development program for the reduction of helicopter drive system weight and cost and the enhancement of reliability and survivability has produced high speed roller bearings, resin-matrix composite rotor shafts and transmission housings, gear/bearing/shaft system integrations, photoelastic investigation methods for gear tooth strength, and the automatic generation of complex FEM models for gear/shaft systems. After describing the design features and performance capabilities of the hardware developed, attention is given to the prospective benefits to be derived from application of these technologies, with emphasis on the relationship between helicopter drive system performance and cost.
A novel ultrasonic clutch using near-field acoustic levitation.
Chang, Kuo-Tsi
2004-10-01
This paper investigates design, fabrication and drive of an ultrasonic clutch with two transducers. For the two transducers, one serving as a driving element of the clutch is connected to a driving shaft via a coupling, and the other serving as a slave element of the clutch is connected to a slave shaft via another coupling. The principle of ultrasonic levitation is first expressed. Then, a series-resonant inverter is used to generate AC voltages at input terminals of each transducer, and a speed measuring system with optic sensors is used to find the relationship between rotational speed of the slave shaft and applied voltage of each transducer. Moreover, contact surfaces of the two transducers are coupled by the frictional force when both the two transducers are not energized, and separated using the ultrasonic levitation when at least one of the two transducers is energized at high voltages at resonance.
Akbari, Omar S.; Chen, Chun-Hong; Marshall, John M.; Huang, Haixia; Antoshechkin, Igor; Hay, Bruce A.
2013-01-01
Insects act as vectors for diseases of plants, animals and humans. Replacement of wild insect populations with genetically modified individuals unable to transmit disease provides a potentially self-perpetuating method of disease prevention. Population replacement requires a gene drive mechanism in order to spread linked genes mediating disease refractoriness through wild populations. We previously reported the creation of synthetic Medea selfish genetic elements able to drive population replacement in Drosophila. These elements use microRNA-mediated silencing of myd88, a maternally expressed gene required for embryonic dorso-ventral pattern formation, coupled with early zygotic expression of a rescuing transgene, to bring about gene drive. Medea elements that work through additional mechanisms are needed in order to be able to carry out cycles of population replacement and/or remove existing transgenes from the population, using second-generation elements that spread while driving first-generation elements out of the population. Here we report the synthesis and population genetic behavior of two new synthetic Medea elements that drive population replacement through manipulation of signaling pathways involved in cellular blastoderm formation or Notch signaling, demonstrating that in Drosophila Medea elements can be generated through manipulation of diverse signaling pathways. We also describe the mRNA and small RNA changes in ovaries and early embryos associated from Medea-bearing females. Finally, we use modeling to illustrate how Medea elements carrying genes that result in diapause-dependent female lethality could be used to bring about population suppression. PMID:23654248
ERIC Educational Resources Information Center
Thomas, Angela
2016-01-01
According to Peha (2016), fiction is all about character. What a character wants, how they go about getting it, and how they change throughout the trajectory of the narrative are key factors that drive a story and make it meaningful. This paper integrates strategies from both narratology (Nikolajeva, 2002; 2005; Rimmon-Kenan, 2002) and linguistics…
NASA Technical Reports Server (NTRS)
Wilcox, Brian H. (Inventor); Nasif, Annette K. (Inventor)
2001-01-01
A vehicle, for driving over a ground surface, has a body with a left side, a right side, a front and a back. The vehicle includes left and right drive mechanisms. Each mechanism includes first and second traction elements for engaging the ground surface and transmitting a driving force between the vehicle and ground surface. Each mechanism includes first and second arms coupled to the first and second traction elements for relative rotation about first and second axis respectively. Each mechanism includes a rotor having a third axis, the rotor coupled to the body for rotation about the third axis and coupled to the first and second arms for relative rotation about the third axis. The mechanism includes first and second drive motors for driving the first and second traction elements and first and second transmissions, driven by the first and second motors and engaging the rotor. Driving the first and second traction elements simultaneously rotates the rotor relative to the first and second arms, respectively.
Zentner, Gabriel E; Wade, Michael J
2017-10-01
Gene drives are selfish genetic elements that use a variety of mechanisms to ensure they are transmitted to subsequent generations at greater than expected frequencies. Synthetic gene drives based on the clustered regularly interspersed palindromic repeats (CRISPR) genome editing system have been proposed as a way to alter the genetic characteristics of natural populations of organisms relevant to the goals of public health, conservation, and agriculture. Here, we review the principles and potential applications of CRISPR drives, as well as means proposed to prevent their uncontrolled spread. We also focus on recent work suggesting that factors such as natural genetic variation and inbreeding may represent substantial impediments to the propagation of CRISPR drives. © 2017 WILEY Periodicals, Inc.
Electromagnetic interference assessment of an ion drive electric propulsion system
NASA Technical Reports Server (NTRS)
Whittlesey, A. C.
1979-01-01
The electromagnetic interference (EMI) form elements of an ion drive electric propulsion system was analyzed, and the effects of EMI interaction with a typical interplanetary spacecraft engineering and scientific subsystems were predicted. SEMCAP, a computerized electromagnetic compatibility assessment code, was used to analyze the impact of EMI noise sources on 65 engineering/telemetry circuits and 48 plasma wave and planetary radio astronomy channels measuring over the range of 100 Hz to 40 MHz in a spacecraft of the Voyager type; manual methods were used to evaluate electrostatics, magnetics, and communications effects. Results indicate that some conducted and radiated spectra are in excess of electromagnetic compatibility specification limits; direct design changes may be required for filtering and shielding of thrust system elements. The worst source of broadband radiated noise appears to be the power processor. The magnetic field necessary to thruster operation is equivalent to about 18 amp-sq m per amp of beam current at right angles to the axis caused by the neutralizer/plume loop.
Robertson, Robyn; Vanlaar, Ward; Simpson, Herb; Boase, Paul
2009-01-01
This article summarizes the main findings from a study designed to examine the legal process in Canada as it applies to alcohol-impaired driving from the point of view of Crown prosecutors and defense counsel, and to identify evidentiary or procedural factors that may impact the legal process, the rights of the accused, and interactions of all parts in the legal process. The data in this study were collected by means of a survey that was mailed out to the population of Crown prosecutors and defense counsel in Canada. In total, 765 prosecutors and 270 defense lawyers or an estimated 33% of all Canadian prosecutors and 15% of defense lawyers completed and returned the questionnaire. The "systems improvement" paradigm was used to interpret the findings and draw conclusions. Such an approach acknowledges the importance of the context in which countermeasures are implemented and delivered and the structures or entities used to deliver countermeasures to a designated target group. Results on type of charges and breath alcohol concentration, caseload, case outcomes, case preparation time, conviction rate at trial and overall conviction rate, reasons for acquittals and time to resolve cases are described. The findings from this national survey suggest that there are important challenges within the criminal justice system that impede the effective and efficient processing of impaired driving cases. Some of these challenges occur as a function of practices and policies, while others occur as a function of legislation. This study illustrates that a "system improvements" approach that acknowledges the importance of all elements of the criminal justice system and the interaction between those elements, can be beneficial in overcoming the alcohol-impaired driving problem.
Maranhão, Geraldo Neves De A.; Brito, Alaan Ubaiara; Leal, Anderson Marques; Fonseca, Jéssica Kelly Silva; Macêdo, Wilson Negrão
2015-01-01
In the present paper, a fuzzy controller applied to a Variable-Speed Drive (VSD) for use in Photovoltaic Pumping Systems (PVPS) is proposed. The fuzzy logic system (FLS) used is embedded in a microcontroller and corresponds to a proportional-derivative controller. A Light-Dependent Resistor (LDR) is used to measure, approximately, the irradiance incident on the PV array. Experimental tests are executed using an Arduino board. The experimental results show that the fuzzy controller is capable of operating the system continuously throughout the day and controlling the direct current (DC) voltage level in the VSD with a good performance. PMID:26402688
Driving Circuitry for Focused Ultrasound Noninvasive Surgery and Drug Delivery Applications
El-Desouki, Munir M.; Hynynen, Kullervo
2011-01-01
Recent works on focused ultrasound (FUS) have shown great promise for cancer therapy. Researchers are continuously trying to improve system performance, which is resulting in an increased complexity that is more apparent when using multi-element phased array systems. This has led to significant efforts to reduce system size and cost by relying on system integration. Although ideas from other fields such as microwave antenna phased arrays can be adopted in FUS, the application requirements differ significantly since the frequency range used in FUS is much lower. In this paper, we review recent efforts to design efficient power monitoring, phase shifting and output driving techniques used specifically for high intensity focused ultrasound (HIFU). PMID:22346589
Driving circuitry for focused ultrasound noninvasive surgery and drug delivery applications.
El-Desouki, Munir M; Hynynen, Kullervo
2011-01-01
Recent works on focused ultrasound (FUS) have shown great promise for cancer therapy. Researchers are continuously trying to improve system performance, which is resulting in an increased complexity that is more apparent when using multi-element phased array systems. This has led to significant efforts to reduce system size and cost by relying on system integration. Although ideas from other fields such as microwave antenna phased arrays can be adopted in FUS, the application requirements differ significantly since the frequency range used in FUS is much lower. In this paper, we review recent efforts to design efficient power monitoring, phase shifting and output driving techniques used specifically for high intensity focused ultrasound (HIFU).
Decrease of dynamic loads in mobile energy means
NASA Astrophysics Data System (ADS)
Polivaev, O. I.; Gorban, L. K.; Vorohobin, A. V.; Vedrinsky, O. S.
2018-03-01
The increase in the productivity of machine and tractor units is possible due to the increase in operating speeds, this leads to the emergence of increased dynamic loads in the system “engine-transmission-propulsion unit-soil”, which worsens the performance of machine-tractor aggregates. To reduce fluctuations in the “engine-transmission” system, special vibration dampers are used, which installed in close proximity to the engine and protect well the transmission from uneven engine operation; however, such dampers practically do not eliminate the oscillations of external loads. Reducing dynamic loads on the transmission and the mobile power engine (MPE) is an important issue directly related to improving the performance, reliability and durability of the tractor, as well as reducing the slippage of the drive wheels. In order to reduce effectively dynamic loads on the transmission and on the MPE, it is necessary to introduce resilient damping elements closer to the sources of oscillations, namely, to the driving wheels. At the same time, the elastic-damping element should provide accumulation of vibration energy caused by external influences and have a large energy capacity. The installation of an elastic-damping element in the final link of the tractor transmission ensures a reduction in the magnitude of external influences, thereby protecting the engine and transmission from large dynamic loads, and allows one to reduce the slippage of the propellers, which has a positive effect on the traction and energy characteristics of the tractor. Traction tests of the LTP-55 tractor on a concrete road showed that the use of an elasto-damping drive makes it possible to increase the maximum tractive power from 33.5 to 35.3 kW and to reduce the slipping of propellers by 12-30%, the specific fuel consumption by 6-10%. When driving on stubble, the use of an elastic-damping drive increases the maximum tractive power from 25 to 26 kW, reduces the skidding of propellers by 10-28%, and the specific fuel consumption by 10-12.5%.
Emergency Warning Systems. Part 2. Warning Systems - Evaluation Guidelines.
1983-07-01
ELEMENT. PROJECT. TASK AREA A WORK UNIT NUMBERS PRC Voorhees Work Unit 2234G 1500 Planning Research Drive McLean, Virginia 22102 ___ 11. CONTROLLING ...different from Controlling Office) IS. SECURITY CLASS. (of this report) Unclassified 15a. DECLASSIFICATION/DOWNGRADING SCHEDULE 16. DISTRIBUTION...systems that control these warning systems are discussed. Test results of several warning systems are included along with a discussion of sound
Treu, C.A. Jr.
1999-08-31
A piezoelectric motor drive circuit is provided which utilizes the piezoelectric elements as oscillators and a Meacham half-bridge approach to develop feedback from the motor ground circuit to produce a signal to drive amplifiers to power the motor. The circuit automatically compensates for shifts in harmonic frequency of the piezoelectric elements due to pressure and temperature changes. 7 figs.
Treu, Jr., Charles A.
1999-08-31
A piezoelectric motor drive circuit is provided which utilizes the piezoelectric elements as oscillators and a Meacham half-bridge approach to develop feedback from the motor ground circuit to produce a signal to drive amplifiers to power the motor. The circuit automatically compensates for shifts in harmonic frequency of the piezoelectric elements due to pressure and temperature changes.
Automated complex for research of electric drives control
NASA Astrophysics Data System (ADS)
Avlasko, P. V.; Antonenko, D. A.
2018-05-01
In the article, the automated complex intended for research of various control modes of electric motors including the inductor motor of double-way feed is described. As a basis of the created complex, the National Instruments platform is chosen. The operating controller built in a platform is delivered with an operating system of real-time for creation of systems of measurement and management. The software developed in the environment of LabVIEW consists of several connected modules which are in different elements of a complex. Besides the software for automated management by experimental installation, the program complex is developed for modelling of processes in the electric drive. As a result there is an opportunity to compare simulated and received experimentally transitional characteristics of the electric drive in various operating modes.
Satellite-instrument system engineering best practices and lessons
NASA Astrophysics Data System (ADS)
Schueler, Carl F.
2009-08-01
This paper focuses on system engineering development issues driving satellite remote sensing instrumentation cost and schedule. A key best practice is early assessment of mission and instrumentation requirements priorities driving performance trades among major instrumentation measurements: Radiometry, spatial field of view and image quality, and spectral performance. Key lessons include attention to technology availability and applicability to prioritized requirements, care in applying heritage, approaching fixed-price and cost-plus contracts with appropriate attention to risk, and assessing design options with attention to customer preference as well as design performance, and development cost and schedule. A key element of success either in contract competition or execution is team experience. Perhaps the most crucial aspect of success, however, is thorough requirements analysis and flowdown to specifications driving design performance with sufficient parameter margin to allow for mistakes or oversights - the province of system engineering from design inception to development, test and delivery.
Goals Analysis Procedure Guidelines for Applying the Goals Analysis Process
NASA Technical Reports Server (NTRS)
Motley, Albert E., III
2000-01-01
One of the key elements to successful project management is the establishment of the "right set of requirements", requirements that reflect the true customer needs and are consistent with the strategic goals and objectives of the participating organizations. A viable set of requirements implies that each individual requirement is a necessary element in satisfying the stated goals and that the entire set of requirements, taken as a whole, is sufficient to satisfy the stated goals. Unfortunately, it is the author's experience that during project formulation phases' many of the Systems Engineering customers do not conduct a rigorous analysis of the goals and objectives that drive the system requirements. As a result, the Systems Engineer is often provided with requirements that are vague, incomplete, and internally inconsistent. To complicate matters, most systems development methodologies assume that the customer provides unambiguous, comprehensive and concise requirements. This paper describes the specific steps of a Goals Analysis process applied by Systems Engineers at the NASA Langley Research Center during the formulation of requirements for research projects. The objective of Goals Analysis is to identify and explore all of the influencing factors that ultimately drive the system's requirements.
Electromagnetic driving units for complex microrobotic systems
NASA Astrophysics Data System (ADS)
Michel, Frank; Ehrfeld, Wolfgang; Berg, Udo; Degen, Reinhard; Schmitz, Felix
1998-10-01
Electromagnetic actuators play an important role in macroscopic robotic systems. In combination with motion transformers, like reducing gear units, angular gears or spindle-screw drives, electromagnetic motors in large product lines ensure the rotational or linear motion of robot driving units and grippers while electromagnets drive valves or part conveyors. In this paper micro actuators and miniaturized motion transformers are introduced which allow a similar development in microrobotics. An electromagnetic motor and a planetary gear box, both with a diameter of 1.9 mm, are already commercially available from the cooperation partner of IMM, the company Dr. Fritz Faulhaber GmbH in Schonaich, Germany. In addition, a motor with a diameter of 2.4 mm is in development. The motors successfully drive an angular gear and a belt drive. A linear stage with a motion range of 7 mm and an overall size as small as 5 X 3.5 X 24 mm3 has been realized involving the motor, a stationary spur gear with zero backlash and a spindle-screw drive. By the use of these commercially available elements complex microrobots can be built up cost-efficiently and rapidly. Furthermore, a batch process has been developed to produce the coils of micro actuator arrays using lithographic techniques with SU-8 resin. In applying these components, the modular construction of complex microrobotic systems becomes feasible.
Design and Performance Analysis of an Intrinsically Safe Ultrasonic Ranging Sensor
Zhang, Hongjuan; Wang, Yu; Zhang, Xu; Wang, Dong; Jin, Baoquan
2016-01-01
In flammable or explosive environments, an ultrasonic sensor for distance measurement poses an important engineering safety challenge, because the driving circuit uses an intermediate frequency transformer as an impedance transformation element, in which the produced heat or spark is available for ignition. In this paper, an intrinsically safe ultrasonic ranging sensor is designed and implemented. The waterproof piezoelectric transducer with integrated transceiver is chosen as an energy transducing element. Then a novel transducer driving circuit is designed based on an impedance matching method considering safety spark parameters to replace an intermediate frequency transformer. Then, an energy limiting circuit is developed to achieve dual levels of over-voltage and over-current protection. The detail calculation and evaluation are executed and the electrical characteristics are analyzed to verify the intrinsic safety of the driving circuit. Finally, an experimental platform of the ultrasonic ranging sensor system is constructed, which involves short-circuit protection. Experimental results show that the proposed ultrasonic ranging sensor is excellent in both ranging performance and intrinsic safety. PMID:27304958
Design and Performance Analysis of an Intrinsically Safe Ultrasonic Ranging Sensor.
Zhang, Hongjuan; Wang, Yu; Zhang, Xu; Wang, Dong; Jin, Baoquan
2016-06-13
In flammable or explosive environments, an ultrasonic sensor for distance measurement poses an important engineering safety challenge, because the driving circuit uses an intermediate frequency transformer as an impedance transformation element, in which the produced heat or spark is available for ignition. In this paper, an intrinsically safe ultrasonic ranging sensor is designed and implemented. The waterproof piezoelectric transducer with integrated transceiver is chosen as an energy transducing element. Then a novel transducer driving circuit is designed based on an impedance matching method considering safety spark parameters to replace an intermediate frequency transformer. Then, an energy limiting circuit is developed to achieve dual levels of over-voltage and over-current protection. The detail calculation and evaluation are executed and the electrical characteristics are analyzed to verify the intrinsic safety of the driving circuit. Finally, an experimental platform of the ultrasonic ranging sensor system is constructed, which involves short-circuit protection. Experimental results show that the proposed ultrasonic ranging sensor is excellent in both ranging performance and intrinsic safety.
NASA Astrophysics Data System (ADS)
Fujiwara, Yukihiro; Yoshii, Masakazu; Arai, Yasuhito; Adachi, Shuichi
Advanced safety vehicle(ASV)assists drivers’ manipulation to avoid trafic accidents. A variety of researches on automatic driving systems are necessary as an element of ASV. Among them, we focus on visual feedback approach in which the automatic driving system is realized by recognizing road trajectory using image information. The purpose of this paper is to examine the validity of this approach by experiments using a radio-controlled car. First, a practical image processing algorithm to recognize white lines on the road is proposed. Second, a model of the radio-controlled car is built by system identication experiments. Third, an automatic steering control system is designed based on H∞ control theory. Finally, the effectiveness of the designed control system is examined via traveling experiments.
Fabrication of piezoelectric ceramic micro-actuator and its reliability for hard disk drives.
Jing, Yang; Luo, Jianbin; Yang, Wenyan; Ju, Guoxian
2004-11-01
A new U-type micro-actuator for precisely positioning a magnetic head in high-density hard disk drives was proposed and developed. The micro-actuator is composed of a U-type stainless steel substrate and two piezoelectric ceramic elements. Using a high-d31 piezoelectric coefficient PMN-PZT ceramic plate and adopting reactive ion etching process fabricate the piezoelectric elements. Reliability against temperature was investigated to ensure the practical application to the drive products. The U-type substrate attached to each side via piezoelectric elements also was simulated by the finite-element method and practically measured by a laser Doppler vibrometer in order to testify the driving mechanics of it. The micro-actuator coupled with two piezoelectric elements featured large displacement of 0.875 microm and high-resonance frequency over 22 kHz. The novel piezoelectric micro-actuators then possess a useful compromise performance to displacement, resonance frequency, and generative force. The results reveal that the new design concept provides a valuable alternative for multilayer piezoelectric micro-actuators.
Magnetic Gearing Versus Conventional Gearing in Actuators for Aerospace Applications
NASA Technical Reports Server (NTRS)
Puchhammer, Gregor
2014-01-01
Magnetic geared actuators (MGA) are designed to perform highly reliable, robust and precise motion on satellite platforms or aerospace vehicles. The design allows MGA to be used for various tasks in space applications. In contrast to conventional geared drives, the contact and lubrication free force transmitting elements lead to a considerable lifetime and range extension of drive systems. This paper describes the fundamentals of magnetic wobbling gears (MWG) and the deduced inherent characteristics, and compares conventional and magnetic gearing.
Analysis and topology optimization design of high-speed driving spindle
NASA Astrophysics Data System (ADS)
Wang, Zhilin; Yang, Hai
2018-04-01
The three-dimensional model of high-speed driving spindle is established by using SOLIDWORKS. The model is imported through the interface of ABAQUS, A finite element analysis model of high-speed driving spindle was established by using spring element to simulate bearing boundary condition. High-speed driving spindle for the static analysis, the spindle of the stress, strain and displacement nephogram, and on the basis of the results of the analysis on spindle for topology optimization, completed the lightweight design of high-speed driving spindle. The design scheme provides guidance for the design of axial parts of similar structures.
Scanning properties of a resonant fiber-optic piezoelectric scanner
NASA Astrophysics Data System (ADS)
Li, Zhi; Yang, Zhe; Fu, Ling
2011-12-01
We develop a resonant fiber-optic scanner using four piezoelectric elements arranged as a square tube, which is efficient to manufacture and drive. Using coupled-field model based on finite element method, scanning properties of the scanner, including vibration mode, resonant frequency, and scanning range, are numerically studied. We also physically measure the effects of geometry sizes and drive signals on the scanning properties, thus providing a foundation for general purpose designs. A scanner adopted in a prototype of imaging system, with a diameter of ˜2 mm and driven by a voltage of 10 V (peak to peak), demonstrates the scanning performance by obtaining an image of resolution target bars. The proposed fiber-optic scanner can be applied to micro-endoscopy that requires two-dimensional scanning of fibers.
Direct drive field actuator motors
Grahn, Allen R.
1998-01-01
A positive-drive field actuator motor including a stator carrying at least one field actuator which changes in dimension responsive to application of an energy field, and at least one drive shoe movable by the dimensional changes of the field actuator to contact and move a rotor element with respect to the stator. Various embodiments of the motor are disclosed, and the rotor element may be moved linearly or arcuately.
Kamm, Gretel B.; López-Leal, Rodrigo; Lorenzo, Juan R.; Franchini, Lucía F.
2013-01-01
The developmental brain gene NPAS3 stands out as a hot spot in human evolution because it contains the largest number of human-specific, fast-evolving, conserved, non-coding elements. In this paper we studied 2xHAR142, one of these elements that is located in the fifth intron of NPAS3. Using transgenic mice, we show that the mouse and chimp 2xHAR142 orthologues behave as transcriptional enhancers driving expression of the reporter gene lacZ to a similar NPAS3 expression subdomain in the mouse central nervous system. Interestingly, the human 2xHAR142 orthologue drives lacZ expression to an extended expression pattern in the nervous system. Thus, molecular evolution of 2xHAR142 provides the first documented example of human-specific heterotopy in the forebrain promoted by a transcriptional enhancer and suggests that it may have contributed to assemble the unique properties of the human brain. PMID:24218632
Tuning CRISPR-Cas9 Gene Drives in Saccharomyces cerevisiae
Roggenkamp, Emily; Giersch, Rachael M.; Schrock, Madison N.; Turnquist, Emily; Halloran, Megan; Finnigan, Gregory C.
2018-01-01
Control of biological populations is an ongoing challenge in many fields, including agriculture, biodiversity, ecological preservation, pest control, and the spread of disease. In some cases, such as insects that harbor human pathogens (e.g., malaria), elimination or reduction of a small number of species would have a dramatic impact across the globe. Given the recent discovery and development of the CRISPR-Cas9 gene editing technology, a unique arrangement of this system, a nuclease-based “gene drive,” allows for the super-Mendelian spread and forced propagation of a genetic element through a population. Recent studies have demonstrated the ability of a gene drive to rapidly spread within and nearly eliminate insect populations in a laboratory setting. While there are still ongoing technical challenges to design of a more optimal gene drive to be used in wild populations, there are still serious ecological and ethical concerns surrounding the nature of this powerful biological agent. Here, we use budding yeast as a safe and fully contained model system to explore mechanisms that might allow for programmed regulation of gene drive activity. We describe four conserved features of all CRISPR-based drives and demonstrate the ability of each drive component—Cas9 protein level, sgRNA identity, Cas9 nucleocytoplasmic shuttling, and novel Cas9-Cas9 tandem fusions—to modulate drive activity within a population. PMID:29348295
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rowsell, David Leon
This report documents the Contractor Readiness Assessment (CRA) for TREAT Fuel Movement and Control Rod Drives Isolation. The review followed the approved Plan of Action (POA) and Implementation Plan (IP) using the identified core requirements. The activity was limited scope focusing on the control rod drives functional isolation and fuel element movement. The purpose of this review is to ensure the facility's readiness to move fuel elements thus supporting inspection and functionally isolate the control rod drives to maintain the required shutdown margin.
Direct-drive field actuator motors
Grahn, Allen R.
1995-01-01
A high-torque, low speed, positive-drive field actuator motor including a stator carrying at least one field actuator which changes in dimension responsive to application of an energy field, and at least one drive shoe movable by the dimensional changes of the field actuator to contact and move a rotor element with respect to the stator. Various embodiments of the motor are disclosed, and the rotor element may be moved linearly or arcuately.
Reducing The Risk Of Fires In Conveyor Transport
NASA Astrophysics Data System (ADS)
Cheremushkina, M. S.; Poddubniy, D. A.
2017-01-01
The paper deals with the actual problem of increasing the safety of operation of belt conveyors in mines. Was developed the control algorithm that meets the technical requirements of the mine belt conveyors, reduces the risk of fires of conveyors belt, and enables energy and resource savings taking into account random sort of traffic. The most effective method of decision such tasks is the construction of control systems with the use of variable speed drives for asynchronous motors. Was designed the mathematical model of the system "variable speed multiengine drive - conveyor - control system of conveyors", that takes into account the dynamic processes occurring in the elements of the transport system, provides an assessment of the energy efficiency of application the developed algorithms, which allows to reduce the dynamic overload in the belt to (15-20)%.
Position control system for use with micromechanical actuators
Guckel, Henry; Stiers, Eric W.
2000-01-01
A positioning system adapted for use with micromechanical actuators provides feedback control of the position of the movable element of the actuator utilizing a low Q sensing coil. The effective inductance of the sensing coil changes with position of the movable element to change the frequency of oscillation of a variable oscillator. The output of the variable oscillator is compared in a phase detector to a reference oscillator signal. The phase detector provides a pulsed output having a pulse duty cycle related to the phase or frequency difference between the oscillator signals. The output of the phase detector is provided to a drive coil which applies a magnetic force to the movable element which balances the force of a spring. The movable element can be displaced to a new position by changing the frequency of the reference oscillator.
Dynamic Analysis of Heavy Vehicle Medium Duty Drive Shaft Using Conventional and Composite Material
NASA Astrophysics Data System (ADS)
Kumar, Ashwani; Jain, Rajat; Patil, Pravin P.
2016-09-01
The main highlight of this study is structural and modal analysis of single piece drive shaft for selection of material. Drive shaft is used for torque carrying from vehicle transmission to rear wheel differential system. Heavy vehicle medium duty transmission drive shaft was selected as research object. Conventional materials (Steel SM45 C, Stainless Steel) and composite materials (HS carbon epoxy, E Glass Polyester Resin Composite) were selected for the analysis. Single piece composite material drive shaft has advantage over conventional two-piece steel drive shaft. It has higher specific strength, longer life, less weight, high critical speed and higher torque carrying capacity. The main criteria for drive shaft failure are strength and weight. Maximum modal frequency obtained is 919 Hz. Various harmful vibration modes (lateral vibration and torsional vibration) were identified and maximum deflection region was specified. For single-piece drive shaft the natural bending frequency should be higher because it is subjected to torsion and shear stress. Single piece drive shaft was modelled using Solid Edge and Pro-E. Finite Element Analysis was used for structural and modal analysis with actual running boundary condition like frictional support, torque and moment. FEA simulation results were validated with experimental literature results.
1994-03-01
products of radial Hankel functions and spherical harmonics. The chosen driving frequency was 474 Hz, corresponding to a value of ka 1, where k is the...spherical harmonics. The chosen driving frequency was 474 Hz, corresponding to a value of ka = 1, where k is the wavenumber of sound in water and a is...wife Adriana for her support, understanding, and for her help in typing this thesis. vi I. INTRODUCTION The utilization of sonar systems in
DOT National Transportation Integrated Search
2017-09-01
This research explores the relationship between the cross-sectional design elements and the impact on selected driver attributes such as speed profiles and lateral positioning. In this experiment a traditional collector-type base roadway of 1.5 miles...
Diesel engine catalytic combustor system. [aircraft engines
NASA Technical Reports Server (NTRS)
Ream, L. W. (Inventor)
1984-01-01
A low compression turbocharged diesel engine is provided in which the turbocharger can be operated independently of the engine to power auxiliary equipment. Fuel and air are burned in a catalytic combustor to drive the turbine wheel of turbine section which is initially caused to rotate by starter motor. By opening a flapper value, compressed air from the blower section is directed to catalytic combustor when it is heated and expanded, serving to drive the turbine wheel and also to heat the catalytic element. To start, engine valve is closed, combustion is terminated in catalytic combustor, and the valve is then opened to utilize air from the blower for the air driven motor. When the engine starts, the constituents in its exhaust gas react in the catalytic element and the heat generated provides additional energy for the turbine section.
Direct drive field actuator motors
Grahn, A.R.
1998-03-10
A positive-drive field actuator motor is described which includes a stator carrying at least one field actuator which changes in dimension responsive to application of an energy field, and at least one drive shoe movable by the dimensional changes of the field actuator to contact and move a rotor element with respect to the stator. Various embodiments of the motor are disclosed, and the rotor element may be moved linearly or arcuately. 62 figs.
Direct-drive field actuator motors
Grahn, A.R.
1995-07-11
A high-torque, low speed, positive-drive field actuator motor is disclosed including a stator carrying at least one field actuator which changes in dimension responsive to application of an energy field, and at least one drive shoe movable by the dimensional changes of the field actuator to contact and move a rotor element with respect to the stator. Various embodiments of the motor are disclosed, and the rotor element may be moved linearly or arcuately. 37 figs.
Fast-Response electric drives of Mechanical Engineering objects
NASA Astrophysics Data System (ADS)
Doykina, L. A.; Bukhanov, S. S.; Gryzlov, A. A.
2018-03-01
The article gives a solution to the problem of increasing the speed in the electrical drives of machine-building enterprises due to the application of a structure with ISC control. In this case, it is possible to get rid of the speed sensors. It is noted that in this case no circulating pulsations are applied to the input of the control system, caused by a non-identical interface between the sensor and the shaft of the operating mechanism. For detailed modeling, a mathematical model of an electric drive with distributed parameters was proposed. The calculation of such system was carried out by the finite element method. Taking into account the distributed characteristic of the system parameters allowed one to take into account the discrete nature of the electric machine’s work. The simulation results showed that the response time in the control circuit is estimated at a time constant of 0.0015, which is about twice as fast as in traditional vector control schemes.
Patch Network for Power Allocation and Distribution in Smart Materials
NASA Technical Reports Server (NTRS)
Golembiewski, Walter T.
2000-01-01
The power allocation and distribution (PAD) circuitry is capable of allocating and distributing a single or multiple sources of power over multi-elements of a power user grid system. The purpose of this invention is to allocate and distribute power that is collected by individual patch rectennas to a region of specific power-user devices, such as actuators. The patch rectenna converts microwave power into DC power. Then this DC power is used to drive actuator devices. However, the power from patch rectennas is not sufficient to drive actuators unless all the collected power is effectively used to drive another group by allocation and distribution. The power allocation and distribution (PAD) circuitry solves the shortfall of power for devices in a large array. The PAD concept is based on the networked power control in which power collected over the whole array of rectennas is allocated to a sub domain where a group of devices is required to be activated for operation. Then the allocated power is distributed to individual element of power-devices in the sub domain according to a selected run-mode.
Impact assessment of land use planning driving forces on environment
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chen, Longgao, E-mail: chenlonggao@163.com; Yang, Xiaoyan; School of Environment and Spatial Informatics, China University of Mining and Technology, Xuzhou 221116
Land use change may exert a negative impact on environmental quality. A state–impact–state (SIS) model describing a state transform under certain impacts has been integrated into land use planning (LUP) environmental impact assessment (LUPEA). This logical model is intuitive and easy to understand, but the exploration of impact is essential to establish the indicator system and to identify the scope of land use environmental impact when it is applied to a specific region. In this study, we investigated environmental driving forces from land use planning (LUPF), along with the conception, components, scope, and impact of LUPF. This method was illustratedmore » by a case study in Zoucheng, China. Through the results, we concluded that (1) the LUPF on environment are impacts originated from the implementation of LUP on a regional environment, which are characterized by four aspects: magnitude, direction, action point, and its owner; (2) various scopes of LUPF on individual environmental elements based on different standards jointly define the final scope of LUPEA; (3) our case study in Zoucheng demonstrates the practicability of this proposed approach; (4) this method can be embedded into LUPEA with direction, magnitudes, and scopes of the LUPF on individual elements obtained, and the identified indicator system can be directly employed into LUPEA and (5) the assessment helps to identify key indicators and to set up a corresponding strategy to mitigate the negative impact of LUP on the environment, which are two important objectives of strategic environmental assessment (SEA) in LUP. - Highlights: • Environmental driving forces from land use planning (LUPF) are investigated and categorized. • Our method can obtains the direction, magnitudes and scopes of environmental driving forces. • The LUPEA scope is determined by the combination of various scopes of LUPF on individual elements. • LUPF assessment can be embedded into LUPEA. • The method can help to identify key indicators and set up a strategy to mitigate negative environmental impact.« less
NASA Technical Reports Server (NTRS)
Solomon, S. C.
1980-01-01
The measurability of changes in plate driving or resistive forces associated with plate boundary earthquakes by laser rangefinding or VLBI is considered with emphasis on those aspects of plate forces that can be characterized by such measurements. Topics covered include: (1) analytic solutions for two dimensional stress diffusion in a plate following earthquake faulting on a finite fault; (2) two dimensional finite-element solutions for the global state of stress at the Earth's surface for possible plate driving forces; and (3) finite-element solutions for three dimensional stress diffusion in a viscoelastic Earth following earthquake faulting.
75 FR 11799 - Fatigue Tolerance Evaluation of Metallic Structures
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-12
...; telephone number (817) 222-5122; facsimile (817) 222-5961; e-mail [email protected] . For legal... rotorcraft components including, but not limited to, rotors, rotor drive systems between the engines and the...'' method is based on crack initiation time in purposely ``flawed'' principal structural elements (PSEs) and...
Possible Orientations of the European Dimension in Romanian Educational Policy
ERIC Educational Resources Information Center
Enache, Roxana
2011-01-01
Curricular reform in any educational system should be to balance national, European or international elements and should integrate diversity. European education calls for a democratic citizenship education that includes a political, cultural, social and economic education--an overall European dimension, which implies an awareness of the drive and…
NASA Astrophysics Data System (ADS)
Sathya, S.; Pavithra, M.; Muruganand, S.
2016-09-01
This paper presents an actuation mechanism based on the interdigitated comb drive MEMS resonator. The important role of that device is to establish MEMS resonators for the second order systems. Comb drive model is one of the basic model which uses the principle of electrostatic and force can be generated for the capacitive sensors. This work is done by overlapping movable and fixed comb fingers which produces an energy. The specific range of the polyimide material properties of young's modulus of 3.1GPa and density of 1300 Kg/m3. Results are shown in the structural domain performance of a lateral motion which corresponds to the applying voltage between the interdigitated comb fingers. It has laterally driven about 40pm with driving voltage. Also the resonance frequency 24Hz and 15Hz with high quality factors are depending on the spring length 260pm and 360pm and structure thickness of 2μm and 5 μm. Here Finite element method (FEM) is used to simulate the various physics scenario and it is designed as two dimensional structure multiphysics domain. The prototype of comb drive MEMS resonator has been suitable for energy harvesting system applications.
NASA Technical Reports Server (NTRS)
1977-01-01
Results of initial tests of the under the wing experimental engine and boilerplate nacelle are presented. The mechanical performance of the engine is reported with emphasis on the advanced technology components. Technology elements of the propulsion system covered include: system dynamics, composite fan blades, reduction gear, lube and accessory drive system, fan frame, inlet, core cowl cooling, fan exhaust nozzle, and digital control system.
40 CFR 1066.830 - Supplemental Federal Test Procedures; overview.
Code of Federal Regulations, 2014 CFR
2014-07-01
... driving and a sequence of vehicle operation that accounts for the impact of the vehicle's air conditioner...) AIR POLLUTION CONTROLS VEHICLE-TESTING PROCEDURES Exhaust Emission Test Procedures for Motor Vehicles... results from the aggressive driving test element (§ 1066.831), the air conditioning test element (§ 1066...
Dynamic Modeling and Soil Mechanics for Path Planning of the Mars Exploration Rovers
NASA Technical Reports Server (NTRS)
Trease, Brian
2011-01-01
To help minimize risk of high sinkage and slippage during drives and to better understand soil properties and rover terramechanics from drive data, a multidisciplinary team was formed under the Mars Exploration Rover project to develop and utilize dynamic computer-based models for rover drives over realistic terrains. The resulting system, named ARTEMIS (Adams-based Rover Terramechanics and Mobility Interaction System), consists of the dynamic model, a library of terramechanics subroutines, and the high-resolution digital elevation maps of the Mars surface. A 200-element model of the rovers was developed and validated for drop tests before launch, using Adams dynamic modeling software. The external library was built in Fortran and called by Adams to model the wheel-soil interactions include the rut-formation effect of deformable soils, lateral and longitudinal forces, bull-dozing effects, and applied wheel torque. The paper presents the details and implementation of the system. To validate the developed system, one study case is presented from a realistic drive on Mars of the Opportunity rover. The simulation results match well from the measurement of on-board telemetry data. In its final form, ARTEMIS will be used in a predictive manner to assess terrain navigability and will become part of the overall effort in path planning and navigation for both Martian and lunar rovers.
Helleu, Quentin; Gérard, Pierre R.; Montchamp-Moreau, Catherine
2015-01-01
Sex chromosome drivers are selfish elements that subvert Mendel's first law of segregation and therefore are overrepresented among the products of meiosis. The sex-biased progeny produced then fuels an extended genetic conflict between the driver and the rest of the genome. Many examples of sex chromosome drive are known, but the occurrence of this phenomenon is probably largely underestimated because of the difficulty to detect it. Remarkably, nearly all sex chromosome drivers are found in two clades, Rodentia and Diptera. Although very little is known about the molecular and cellular mechanisms of drive, epigenetic processes such as chromatin regulation could be involved in many instances. Yet, its evolutionary consequences are far-reaching, from the evolution of mating systems and sex determination to the emergence of new species. PMID:25524548
Chromatic Modulator for High Resolution CCD or APS Devices
NASA Technical Reports Server (NTRS)
Hartley, Frank T. (Inventor); Hull, Anthony B. (Inventor)
2003-01-01
A system for providing high-resolution color separation in electronic imaging. Comb drives controllably oscillate a red-green-blue (RGB) color strip filter system (or otherwise) over an electronic imaging system such as a charge-coupled device (CCD) or active pixel sensor (APS). The color filter is modulated over the imaging array at a rate three or more times the frame rate of the imaging array. In so doing, the underlying active imaging elements are then able to detect separate color-separated images, which are then combined to provide a color-accurate frame which is then recorded as the representation of the recorded image. High pixel resolution is maintained. Registration is obtained between the color strip filter and the underlying imaging array through the use of electrostatic comb drives in conjunction with a spring suspension system.
Coupling vibration research on Vehicle-bridge system
NASA Astrophysics Data System (ADS)
Zhou, Jiguo; Wang, Guihua
2018-01-01
The vehicle-bridge coupling system forms when vehicle running on a bridge. It will generate a relatively large influence on the driving comfort and driving safe when the vibration of the vehicle is bigger. A three-dimensional vehicle-bridge system with biaxial seven degrees of freedom has been establish in this paper based on finite numerical simulation. Adopting the finite element transient numerical simulation to realize the numerical simulation of vehicle-bridge system coupling vibration. Then, analyze the dynamic response of vehicle and bridge while different numbers of vehicles running on the bridge. Got the variation rule of vertical vibration of car body and bridge, and that of the contact force between the wheel and bridge deck. The research results have a reference value for the analysis about the vehicle running on a large-span cabled bridge.
Confinement of gene drive systems to local populations: A comparative analysis
Marshall, John M.; Hay, Bruce A.
2011-01-01
Mosquito-borne diseases such as malaria and dengue fever pose a major health problem through much of the world. One approach to disease prevention involves the use of selfish genetic elements to drive disease-refractory genes into wild mosquito populations. Recently engineered synthetic drive systems have provided encouragement for this strategy; but at the same time have been greeted with caution over the concern that transgenes may spread into countries and communities without their consent. Consequently, there is also interest in gene drive systems that, while strong enough to bring about local population replacement, are unable to establish themselves beyond a partially-isolated release site, at least during the testing phase. Here, we develop simple deterministic and stochastic models to compare the confinement properties of a variety of gene drive systems. Our results highlight several systems with desirable features for confinement – a high migration rate required to become established in neighboring populations, and low-frequency persistence in neighboring populations for moderate migration rates. Single-allele underdominance and single-locus engineered underdominance have the strongest confinement properties, but are difficult to engineer and require a high introduction frequency, respectively. Toxin-antidote systems such as Semele, Merea and two-locus engineered underdominance show promising confinement properties and require lower introduction frequencies. Killer-rescue is self-limiting in time, but is able to disperse to significant levels in neighboring populations. We discuss the significance of these results in the context of a phased release of transgenic mosquitoes, and the need for characterization of local ecology prior to a release. PMID:22094363
DOE Office of Scientific and Technical Information (OSTI.GOV)
Guo, Y.; Parsons, T.; King, R.
This report summarizes the theory, verification, and validation of a new sizing tool for wind turbine drivetrain components, the Drivetrain Systems Engineering (DriveSE) tool. DriveSE calculates the dimensions and mass properties of the hub, main shaft, main bearing(s), gearbox, bedplate, transformer if up-tower, and yaw system. The level of fi¬ delity for each component varies depending on whether semiempirical parametric or physics-based models are used. The physics-based models have internal iteration schemes based on system constraints and design criteria. Every model is validated against available industry data or finite-element analysis. The verification and validation results show that the models reasonablymore » capture primary drivers for the sizing and design of major drivetrain components.« less
2012-01-01
The fast and accurate computation of the electric forces that drive the motion of charged particles at the nanometer scale represents a computational challenge. For this kind of system, where the discrete nature of the charges cannot be neglected, boundary element methods (BEM) represent a better approach than finite differences/finite elements methods. In this article, we compare two different BEM approaches to a canonical electrostatic problem in a three-dimensional space with inhomogeneous dielectrics, emphasizing their suitability for particle-based simulations: the iterative method proposed by Hoyles et al. and the Induced Charge Computation introduced by Boda et al. PMID:22338640
Berti, Claudio; Gillespie, Dirk; Eisenberg, Robert S; Fiegna, Claudio
2012-02-16
The fast and accurate computation of the electric forces that drive the motion of charged particles at the nanometer scale represents a computational challenge. For this kind of system, where the discrete nature of the charges cannot be neglected, boundary element methods (BEM) represent a better approach than finite differences/finite elements methods. In this article, we compare two different BEM approaches to a canonical electrostatic problem in a three-dimensional space with inhomogeneous dielectrics, emphasizing their suitability for particle-based simulations: the iterative method proposed by Hoyles et al. and the Induced Charge Computation introduced by Boda et al.
Effects of familial climate on the adolescents' driving habits: a recent literature.
Foo, K Y
2015-01-01
Driving is a functional task that requires a complex interaction of visual perception, cognitive and motor skills. Next to circulatory diseases and cancer, road accidents remain the third epidemic cause of death internationally, with approximately half a million teen drivers killed annually. Driver behaviour has been cited as the pervasive marker of automotive crashes. A reliable and firm relationship between the positive parental model, message, and communication has been established. Specifically, the familial climate is proposed to be an important element of reinforcement, modelling, support and environmental determinant in interpreting personal perceptions, habits, values, and belief system. Confirming the assertion, this bibliographic review presents the most recent research findings on the contributions of families to the driving habits of teens. The emphasis is speculated on parental alcohol use, aggressiveness, attention-deficit/hyperactivity disorder, relationship, and intergenerational transmission of driving styles. Besides, the effects of familial supervision, monitoring, education and awareness, and genders, partners, and demographic influence on the driving habits are discussed and outlined.
Life analysis of multiroller planetary traction drive
NASA Technical Reports Server (NTRS)
Coy, J. J.; Rohn, D. A.; Loewenthal, S. H.
1981-01-01
A contact fatigue life analysis was performed for a constant ratio, Nasvytis Multiroller Traction Drive. The analysis was based on the Lundberg-Palmgren method for rolling element bearing life prediction. Life adjustment factors for materials, processing, lubrication and traction were included. The 14.7 to 1 ratio drive consisted of a single stage planetary configuration with two rows of stepped planet rollers of five rollers per row, having a roller cluster diameter of approximately 0.21 m, a width of 0.06 m and a weight of 9 kg. Drive system 10 percent life ranged from 18,800 hours at 16.6 kW (22.2 hp) and 25,000 rpm sun roller speed, to 305 hours at maximum operating conditions of 149 kw (200 hp) and 75,000 rpm sun roller speed. The effect of roller diameter and roller center location on life were determined. It was found that an optimum life geometry exists.
Li, Yi; Chen, Yuren
2016-12-30
To make driving assistance system more humanized, this study focused on the prediction and assistance of drivers' perception-response time on mountain highway curves. Field tests were conducted to collect real-time driving data and driver vision information. A driver-vision lane model quantified curve elements in drivers' vision. A multinomial log-linear model was established to predict perception-response time with traffic/road environment information, driver-vision lane model, and mechanical status (last second). A corresponding assistance model showed a positive impact on drivers' perception-response times on mountain highway curves. Model results revealed that the driver-vision lane model and visual elements did have important influence on drivers' perception-response time. Compared with roadside passive road safety infrastructure, proper visual geometry design, timely visual guidance, and visual information integrality of a curve are significant factors for drivers' perception-response time.
Wu, Bobo; Shen, Xianbao; Cao, Xinyue; Yao, Zhiliang; Wu, Yunong
2016-05-01
The composition of diesel exhaust fine particulate matter (PM2.5) is of growing interest because of its impacts on health and climatic factors and its application in source apportionment and aerosol modeling. We characterized the detailed chemical composition of the PM2.5, including the organic carbon (OC), elemental carbon (EC), water-soluble ions (WSIs), and elemental contents, emitted from China III and China IV diesel trucks (nine each) based on real-world measurements in Beijing using a portable emissions measurement system (PEMS). Carbonaceous compounds were the dominant components (totaling approximately 87%) of the PM2.5, similar to the results (greater than 80% of the PM2.5) of our previous study of on-road China III diesel trucks. In general, the amounts of individual component groups (carbonaceous compounds, WSIs, and elements) and PM2.5 emissions for China IV diesel trucks were lower than those of China III diesel trucks of the same size, except for the WSIs and elements for the light- and medium-duty diesel trucks. The EC/OC mass ratios were strongly dependent on the emission standards, and the ratios of China IV diesel trucks were higher than those of China III diesel trucks of the same size. The chemical species in the PM2.5 were significantly affected by the driving conditions. Overall, the emission factors (EFs) of the PM2.5 and OC under non-highway (NHW) driving conditions were higher than those under highway (HW) driving conditions, and the EC/OC mass ratios presented an increasing trend, with decreasing OC/PM2.5 and increasing EC/PM2.5 from NHW to HW driving conditions; similar trends were reported in our previous study. In addition, Pearson's correlation coefficients among the PM2.5 species were analyzed to determine the relationships among the various chemical components. Copyright © 2016 Elsevier B.V. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Martin-Aranda, Maria; Rementeria, Rosalia; Hackenberg, Robert Errol
Here, the goal of this paper is to analyse the effect of adding Al on the non-steady pearlite growth occurring in a Fe–C–Mn system. The results are discussed in terms of the partitioning of elements across the austenite/ferrite and austenite/cementite interfaces, and the modification of the pearlite driving force related to the change in carbon activity in austenite.
Chaotic Dynamics and Application of LCR Oscillators Sharing Common Nonlinearity
NASA Astrophysics Data System (ADS)
Jeevarekha, A.; Paul Asir, M.; Philominathan, P.
2016-06-01
This paper addresses the problem of sharing common nonlinearity among nonautonomous and autonomous oscillators. By choosing a suitable common nonlinear element with the driving point characteristics capable of bringing out chaotic motion in a combined system, we obtain identical chaotic states. The dynamics of the coupled system is explored through numerical and experimental studies. Employing the concept of common nonlinearity, a simple chaotic communication system is modeled and its performance is verified through Multisim simulation.
DeWall, Kevin G.; Watkins, John C; Nitzel, Michael E.
2006-08-29
Apparatus for actuating a valve includes a support frame and at least one valve driving linkage arm, one end of which is rotatably connected to a valve stem of the valve and the other end of which is rotatably connected to a screw block. A motor connected to the frame is operatively connected to a motor driven shaft which is in threaded screw driving relationship with the screw block. The motor rotates the motor driven shaft which drives translational movement of the screw block which drives rotatable movement of the valve driving linkage arm which drives translational movement of the valve stem. The valve actuator may further include a sensory control element disposed in operative relationship with the valve stem, the sensory control element being adapted to provide control over the position of the valve stem by at least sensing the travel and/or position of the valve stem.
USDA-ARS?s Scientific Manuscript database
Fusarium verticillioides is an agriculturally important fungus because of its association with maize and its propensity to contaminate grain with toxic compounds. Some isolates of the fungus harbor a meiotic drive element known as Spore killer (SkK) that causes nearly all surviving meiotic progeny f...
Simulation of hybrid propulsion system using LSRG and single cylinder engine
NASA Astrophysics Data System (ADS)
Han, C.; Ohyama, K.; Wang, W. Q.
2017-11-01
Nowadays, more and more people are beginning to use hybrid vehicles (HVs). The drive system of HVs needs to produce the electric energy with the electric generator and gearbox powered by an engine. Therefore, the structure becomes complex and the cost is high. To solve this issue, this research proposes a new drive system design that combines the engine and a linear switched reluctance generator (LSRG). When the engine is operating, the LSRG can simultaneously assist the engine’s mechanical output or can generate power to charge the battery. In this research, three research steps are executed. In the first step, the LSRG is designed according to the size of normal engine. Then, finite element analysis is used to get the data of flux linkage and calculate the inductance and translator force. Finally, Simulink models of control system are constructed to verify the performance of LSRG.
Helleu, Quentin; Gérard, Pierre R; Montchamp-Moreau, Catherine
2014-12-18
Sex chromosome drivers are selfish elements that subvert Mendel's first law of segregation and therefore are overrepresented among the products of meiosis. The sex-biased progeny produced then fuels an extended genetic conflict between the driver and the rest of the genome. Many examples of sex chromosome drive are known, but the occurrence of this phenomenon is probably largely underestimated because of the difficulty to detect it. Remarkably, nearly all sex chromosome drivers are found in two clades, Rodentia and Diptera. Although very little is known about the molecular and cellular mechanisms of drive, epigenetic processes such as chromatin regulation could be involved in many instances. Yet, its evolutionary consequences are far-reaching, from the evolution of mating systems and sex determination to the emergence of new species. Copyright © 2015 Cold Spring Harbor Laboratory Press; all rights reserved.
Autonomous vehicles: from paradigms to technology
NASA Astrophysics Data System (ADS)
Ionita, Silviu
2017-10-01
Mobility is a basic necessity of contemporary society and it is a key factor in global economic development. The basic requirements for the transport of people and goods are: safety and duration of travel, but also a number of additional criteria are very important: energy saving, pollution, passenger comfort. Due to advances in hardware and software, automation has penetrated massively in transport systems both on infrastructure and on vehicles, but man is still the key element in vehicle driving. However, the classic concept of ‘human-in-the-loop’ in terms of ‘hands on’ in driving the cars is competing aside from the self-driving startups working towards so-called ‘Level 4 autonomy’, which is defined as “a self-driving system that does not requires human intervention in most scenarios”. In this paper, a conceptual synthesis of the autonomous vehicle issue is made in connection with the artificial intelligence paradigm. It presents a classification of the tasks that take place during the driving of the vehicle and its modeling from the perspective of traditional control engineering and artificial intelligence. The issue of autonomous vehicle management is addressed on three levels: navigation, movement in traffic, respectively effective maneuver and vehicle dynamics control. Each level is then described in terms of specific tasks, such as: route selection, planning and reconfiguration, recognition of traffic signs and reaction to signaling and traffic events, as well as control of effective speed, distance and direction. The approach will lead to a better understanding of the way technology is moving when talking about autonomous cars, smart/intelligent cars or intelligent transport systems. Keywords: self-driving vehicle, artificial intelligence, deep learning, intelligent transport systems.
Design and simulation of a new bidirectional actuator for haptic systems featuring MR fluid
NASA Astrophysics Data System (ADS)
Hung, Nguyen Quoc; Tri, Diep Bao; Cuong, Vo Van; Choi, Seung-Bok
2017-04-01
In this research, a new configuration of bidirectional actuator featuring MR fluid (BMRA) is proposed for haptic application. The proposed BMRA consists of a driving disc, a driving housing and a driven disc. The driving disc is placed inside the driving housing and rotates counter to each other by a servo DC motor and a bevel gear system. The driven shaft is also placed inside the housing and next to the driving disc. The gap between the two disc and the gap between the discs and the housing are filled with MR fluid. On the driven disc, two mutual magnetic coils are placed. By applying currents to the two coils mutually, the torque at the output shaft, which is fixed to the driven disc, can be controlled with positive, zero or negative value. This make the actuator be suitable for haptic application. After a review of MR fluid and its application, configuration of the proposed BMRA is presented. The modeling of the actuator is then derived based on Bingham rheological model of MRF and magnetic finite element analysis (FEA). The optimal design of the actuator is then performed to minimize the mass of the BMRA. From the optimal design result, performance characteristics of the actuator is simulated and detailed design of a prototype actuator is conducted.
NASA Astrophysics Data System (ADS)
Honma, Hiroaki; Takahashi, Kazuhiro; Ishida, Makoto; Sawada, Kazuaki
2012-11-01
This paper reports on the construction of a nano-electro-mechanical system (NEMS) tunable color filter based on a subwavelength grating with high color uniformity and a low drive voltage. We recently proposed a ground-voltage-ground (GVG)-type tunable color filter with a parallel-plate actuator with three pairs of electrodes to decrease the crosstalk due to the electrostatic attractive force between each pair of actuators. Our finite element method (FEM) simulation results indicate that the drive voltage is decreased by 10 V, as compared to that of the previously reported GV type. The proposed structure was fabricated using a silicon-on-insulator (SOI) wafer. The color tuning capability of the device was demonstrated by applying a drive voltage of 6.7 V. The reflected light intensity was decreased by 34% at a wavelength of 680 nm. Color uniformity was also obtained in the filter area by reducing the variation of the displacement on the one-dimensional actuator arrays.
1980-10-01
Element, 64709N Prototype Manpower/Personnel Systems (U), Project Z1302-PN Officer Career Models (U), funded by the Office of the Deputy Assistant... Models for Navy Officer Billets portion of the proposed NPS research effort to develop an integrated officer system planning model ; the purpose of this...attempting to model the Naval officer force structure as a system. This study considers the primary first order factors which drive the requirements
Post, Richard Freeman [Walnut Creek, CA
2006-08-29
A simple permanent-magnet-excited maglev geometry provides levitation forces and is stable against vertical displacements from equilibrium but is unstable against horizontal displacements. An Inductrack system is then used in conjunction with this system to effect stabilization against horizontal displacements and to provide centering forces to overcome centrifugal forces when the vehicle is traversing curved sections of a track or when any other transient horizontal force is present. In some proposed embodiments, the Inductrack track elements are also employed as the stator of a linear induction-motor drive and braking system.
Post, Richard Freeman
2003-10-07
A simple permanent-magnet-excited maglev geometry provides levitation forces and is stable against vertical displacements from equilibrium but is unstable against horizontal displacements. An Inductrack system is then used in conjunction with this system to effect stabilization against horizontal displacements and to provide centering forces to overcome centrifugal forces when the vehicle is traversing curved sections of a track or when any other transient horizontal force is present. In some proposed embodiments, the Inductrack track elements are also employed as the stator of a linear induction-motor drive and braking system.
The Electrical Power System of HTV
NASA Astrophysics Data System (ADS)
Kiewe, Bernhard; Maejima, Takaharu
2005-05-01
The paper describes the power system of H2-Transfer Vehicle with special focus on the Power Control Unit (PCU). This PCU is the main element of the solar generator power system, operating 30 solar sections in their maximum power point individually and controlling the state of charge of the rechargeable Li- Ion battery. The driving requirements for the PCU are summarized in this paper. The design of the main functions is described and a summary of the performance test results is given.
1988-05-01
fluctuations were measured with a fast response resistance bridge driving microthermal sensor probes as the temperature sensitive resistance elements. The bridge...used was a Thermo Systems, Inc. (TSI) type 1044, dc Wheatstone bridge with a frequency response of 800 hz. The microthermal probes were TSI type 1210
Ward, Catherine M; Su, Jessica T; Huang, Yunxin; Lloyd, Alun L; Gould, Fred; Hay, Bruce A
2011-04-01
One strategy for controlling transmission of insect-borne disease involves replacing the native insect population with transgenic animals unable to transmit disease. Population replacement requires a drive mechanism to ensure the rapid spread of linked transgenes, the presence of which may result in a fitness cost to carriers. Medea selfish genetic elements have the feature that when present in a female, only offspring that inherit the element survive, a behavior that can lead to spread. Here, we derive equations that describe the conditions under which Medea elements with a fitness cost will spread, and the equilibrium allele frequencies are achieved. Of particular importance, we show that whenever Medea spreads, the non-Medea genotype is driven out of the population, and we estimate the number of generations required to achieve this goal for Medea elements with different fitness costs and male-only introduction frequencies. Finally, we characterize two contexts in which Medea elements with fitness costs drive the non-Medea allele from the population: an autosomal element in which not all Medea-bearing progeny of a Medea-bearing mother survive, and an X-linked element in species in which X/Y individuals are male. Our results suggest that Medea elements can drive population replacement under a wide range of conditions. © 2010 The Author(s). Evolution© 2010 The Society for the Study of Evolution.
Experiments and simulation of thermal behaviors of the dual-drive servo feed system
NASA Astrophysics Data System (ADS)
Yang, Jun; Mei, Xuesong; Feng, Bin; Zhao, Liang; Ma, Chi; Shi, Hu
2015-01-01
The machine tool equipped with the dual-drive servo feed system could realize high feed speed as well as sharp precision. Currently, there is no report about the thermal behaviors of the dual-drive machine, and the current research of the thermal characteristics of machines mainly focuses on steady simulation. To explore the influence of thermal characterizations on the precision of a jib boring machine assembled dual-drive feed system, the thermal equilibrium tests and the research on thermal-mechanical transient behaviors are carried out. A laser interferometer, infrared thermography and a temperature-displacement acquisition system are applied to measure the temperature distribution and thermal deformation at different feed speeds. Subsequently, the finite element method (FEM) is used to analyze the transient thermal behaviors of the boring machine. The complex boundary conditions, such as heat sources and convective heat transfer coefficient, are calculated. Finally, transient variances in temperatures and deformations are compared with the measured values, and the errors between the measurement and the simulation of the temperature and the thermal error are 2 °C and 2.5 μm, respectively. The researching results demonstrate that the FEM model can predict the thermal error and temperature distribution very well under specified operating condition. Moreover, the uneven temperature gradient is due to the asynchronous dual-drive structure that results in thermal deformation. Additionally, the positioning accuracy decreases as the measured point became further away from the motor, and the thermal error and equilibrium period both increase with feed speeds. The research proposes a systematical method to measure and simulate the boring machine transient thermal behaviors.
NASA Technical Reports Server (NTRS)
Blumrich, J. F. (Inventor)
1974-01-01
The apparatus consists of a wheel having a hub with radially disposed spokes which are provided with a plurality of circumferential rim segments. These rim segments carry, between the spokes, rim elements which are rigid relative to their outer support surfaces, and defined in their outer contour to form a part of the circle forming the wheel diameter. The rim segments have provided for each of the rim elements an independent drive means selectively operable when the element is in ground contact to rotatably drive the rim element in a direction of movement perpendicularly lateral to the normal plane of rotation and movement of the wheel. This affords the wheel omnidirectional movement.
Superadiabatic driving of a three-level quantum system
NASA Astrophysics Data System (ADS)
Theisen, M.; Petiziol, F.; Carretta, S.; Santini, P.; Wimberger, S.
2017-07-01
We study superadiabatic quantum control of a three-level quantum system whose energy spectrum exhibits multiple avoided crossings. In particular, we investigate the possibility of treating the full control task in terms of independent two-level Landau-Zener problems. We first show that the time profiles of the elements of the full control Hamiltonian are characterized by peaks centered around the crossing times. These peaks decay algebraically for large times. In principle, such a power-law scaling invalidates the hypothesis of perfect separability. Nonetheless, we address the problem from a pragmatic point of view by studying the fidelity obtained through separate control as a function of the intercrossing separation. This procedure may be a good approach to achieve approximate adiabatic driving of a specific instantaneous eigenstate in realistic implementations.
Automatic control of the preload in adaptive friction drives of chemical production machines
NASA Astrophysics Data System (ADS)
Balakin, P. D.
2017-08-01
Being based on the principle of providing the systems with adaptation property to the real parameters and operational condition, the energy effective mechanical system constructed on the base of friction gear with automated preload is offered and this allows keeping mechanical efficiency value adequate transforming drive path to in the terms of multimode operation. This is achieved by integrated control loop, operating on the basis of the laws of motion with the energy of the main power flow by changing automatically the kinematic dimension of the section and, hence, the value of preload in the friction contact. The given ratios of forces and deformations in the control loop are required at the stage of conceptual design to determine design dimensions of power transmission elements with new properties.
Review. Neurobiological mechanisms for opponent motivational processes in addiction.
Koob, George F; Le Moal, Michel
2008-10-12
The conceptualization of drug addiction as a compulsive disorder with excessive drug intake and loss of control over intake requires motivational mechanisms. Opponent process as a motivational theory for the negative reinforcement of drug dependence has long required a neurobiological explanation. Key neurochemical elements involved in reward and stress within basal forebrain structures involving the ventral striatum and extended amygdala are hypothesized to be dysregulated in addiction to convey the opponent motivational processes that drive dependence. Specific neurochemical elements in these structures include not only decreases in reward neurotransmission such as dopamine and opioid peptides in the ventral striatum, but also recruitment of brain stress systems such as corticotropin-releasing factor (CRF), noradrenaline and dynorphin in the extended amygdala. Acute withdrawal from all major drugs of abuse produces increases in reward thresholds, anxiety-like responses and extracellular levels of CRF in the central nucleus of the amygdala. CRF receptor antagonists block excessive drug intake produced by dependence. A brain stress response system is hypothesized to be activated by acute excessive drug intake, to be sensitized during repeated withdrawal, to persist into protracted abstinence and to contribute to stress-induced relapse. The combination of loss of reward function and recruitment of brain stress systems provides a powerful neurochemical basis for the long hypothesized opponent motivational processes responsible for the negative reinforcement driving addiction.
Integrated computer-aided design using minicomputers
NASA Technical Reports Server (NTRS)
Storaasli, O. O.
1980-01-01
Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM), a highly interactive software, has been implemented on minicomputers at the NASA Langley Research Center. CAD/CAM software integrates many formerly fragmented programs and procedures into one cohesive system; it also includes finite element modeling and analysis, and has been interfaced via a computer network to a relational data base management system and offline plotting devices on mainframe computers. The CAD/CAM software system requires interactive graphics terminals operating at a minimum of 4800 bits/sec transfer rate to a computer. The system is portable and introduces 'interactive graphics', which permits the creation and modification of models interactively. The CAD/CAM system has already produced designs for a large area space platform, a national transonic facility fan blade, and a laminar flow control wind tunnel model. Besides the design/drafting element analysis capability, CAD/CAM provides options to produce an automatic program tooling code to drive a numerically controlled (N/C) machine. Reductions in time for design, engineering, drawing, finite element modeling, and N/C machining will benefit productivity through reduced costs, fewer errors, and a wider range of configuration.
Data That Drive: Closing the Loop in the Learning Hospital System
Liu, Vincent X.; Morehouse, John W.; Baker, Jennifer M.; Greene, John D.; Kipnis, Patricia; Escobar, Gabriel J.
2017-01-01
The learning healthcare system describes a vision of US healthcare that capitalizes on science, information technology, incentives, and care culture to drive improvements in the quality of health care. The inpatient setting, one of the most costly and impactful domains of healthcare, is an ideal setting in which to use data and information technology to foster continuous learning and quality improvement. The rapid digitization of inpatient medicine offers incredible new opportunities to use data from routine care to generate new discovery and thus close the virtuous cycle of learning. We use an object lesson—sepsis care within the 21 hospitals of the Kaiser Permanente Northern California integrated healthcare delivery system—to offer insight into the critical elements necessary for developing a learning hospital system. We then describe how a hospital-wide data-driven approach to inpatient care can facilitate improvements in the quality of hospital care. PMID:27805797
Ontology-Based Architecture for Intelligent Transportation Systems Using a Traffic Sensor Network.
Fernandez, Susel; Hadfi, Rafik; Ito, Takayuki; Marsa-Maestre, Ivan; Velasco, Juan R
2016-08-15
Intelligent transportation systems are a set of technological solutions used to improve the performance and safety of road transportation. A crucial element for the success of these systems is the exchange of information, not only between vehicles, but also among other components in the road infrastructure through different applications. One of the most important information sources in this kind of systems is sensors. Sensors can be within vehicles or as part of the infrastructure, such as bridges, roads or traffic signs. Sensors can provide information related to weather conditions and traffic situation, which is useful to improve the driving process. To facilitate the exchange of information between the different applications that use sensor data, a common framework of knowledge is needed to allow interoperability. In this paper an ontology-driven architecture to improve the driving environment through a traffic sensor network is proposed. The system performs different tasks automatically to increase driver safety and comfort using the information provided by the sensors.
Ontology-Based Architecture for Intelligent Transportation Systems Using a Traffic Sensor Network
Fernandez, Susel; Hadfi, Rafik; Ito, Takayuki; Marsa-Maestre, Ivan; Velasco, Juan R.
2016-01-01
Intelligent transportation systems are a set of technological solutions used to improve the performance and safety of road transportation. A crucial element for the success of these systems is the exchange of information, not only between vehicles, but also among other components in the road infrastructure through different applications. One of the most important information sources in this kind of systems is sensors. Sensors can be within vehicles or as part of the infrastructure, such as bridges, roads or traffic signs. Sensors can provide information related to weather conditions and traffic situation, which is useful to improve the driving process. To facilitate the exchange of information between the different applications that use sensor data, a common framework of knowledge is needed to allow interoperability. In this paper an ontology-driven architecture to improve the driving environment through a traffic sensor network is proposed. The system performs different tasks automatically to increase driver safety and comfort using the information provided by the sensors. PMID:27537878
Adaptive Role-Play Exercises for a Leader Development Center
2006-11-01
OR GRANT NUMBER W91 FD3-06-P-0023 Adaptive Role-Play Exercises for a Leader Development Center 5b. PROGRAM ELEMENT NUMBER 665502 6. AUTHOR(S): 5c...PROJECT NUMBER M770 Michael Hertz (Progeny Systems Corporation) 5d. TASK NUMBER 103 5e. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS...ES) 8. PERFORMING ORGANIZATION REPORT NUMBER Progeny Systems Corporation 9500 Innovation Drive Manassas, VA 20110 9. SPONSORING/MONITORING AGENCY NAME
NASA Astrophysics Data System (ADS)
Abdullah, Oday I.; Schlattmann, Josef; Senatore, Adolfo; Al-Shabibi, Abdullah M.
2018-05-01
The designers of friction clutch systems in vehicular applications should always take into account a number of essential criteria. The friction clutch should be able to transfer the torque from the driving shaft to the driven one within a short time and minimum amount of shocks and vibrations to make the engagement (disengagement) as gentle as possible. Furthermore, it is well known that high surface temperatures were noticed during the beginning of engagement period due to slipping between the contacting elements of the friction clutch system with ensuing heat generation. The transient thermoelastic problem of multi-disc systems has been deeply investigated by many scientists and researchers using numerical techniques such as finite element method. In this analysis, the influence of the sliding speed on the thermoelastic behavior when the initial heat generated is constant was studied. For this purpose an axisymmetric finite element models were developed and used in the simulation shown in the paper.
Brun, Klaus; Gernentz, Ryan S.
2010-07-27
A method and system for fine-tuning the motion of suction or discharge valves associated with cylinders of a reciprocating gas compressor, such as the large compressors used for natural gas transmission. The valve's primary driving force is conventional, but the valve also uses an electromagnetic coil to sense position of the plate (or other plugging element) and to provide an opposing force prior to impact.
Human Guidance Behavior Decomposition and Modeling
NASA Astrophysics Data System (ADS)
Feit, Andrew James
Trained humans are capable of high performance, adaptable, and robust first-person dynamic motion guidance behavior. This behavior is exhibited in a wide variety of activities such as driving, piloting aircraft, skiing, biking, and many others. Human performance in such activities far exceeds the current capability of autonomous systems in terms of adaptability to new tasks, real-time motion planning, robustness, and trading safety for performance. The present work investigates the structure of human dynamic motion guidance that enables these performance qualities. This work uses a first-person experimental framework that presents a driving task to the subject, measuring control inputs, vehicle motion, and operator visual gaze movement. The resulting data is decomposed into subspace segment clusters that form primitive elements of action-perception interactive behavior. Subspace clusters are defined by both agent-environment system dynamic constraints and operator control strategies. A key contribution of this work is to define transitions between subspace cluster segments, or subgoals, as points where the set of active constraints, either system or operator defined, changes. This definition provides necessary conditions to determine transition points for a given task-environment scenario that allow a solution trajectory to be planned from known behavior elements. In addition, human gaze behavior during this task contains predictive behavior elements, indicating that the identified control modes are internally modeled. Based on these ideas, a generative, autonomous guidance framework is introduced that efficiently generates optimal dynamic motion behavior in new tasks. The new subgoal planning algorithm is shown to generate solutions to certain tasks more quickly than existing approaches currently used in robotics.
Design and performance testing of an ultrasonic linear motor with dual piezoelectric actuators.
Smithmaitrie, Pruittikorn; Suybangdum, Panumas; Laoratanakul, Pitak; Muensit, Nantakan
2012-05-01
In this work, design and performance testing of an ultrasonic linear motor with dual piezoelectric actuator patches are studied. The motor system consists of a linear stator, a pre-load weight, and two piezoelectric actuator patches. The piezoelectric actuators are bonded with the linear elastic stator at specific locations. The stator generates propagating waves when the piezoelectric actuators are subjected to harmonic excitations. Vibration characteristics of the linear stator are analyzed and compared with finite element and experimental results. The analytical, finite element, and experimental results show agreement. In the experiments, performance of the ultrasonic linear motor is tested. Relationships between velocity and pre-load weight, velocity and applied voltage, driving force and applied voltage, and velocity and driving force are reported. The design of the dual piezoelectric actuators yields a simpler structure with a smaller number of actuators and lower stator stiffness compared with a conventional design of an ultrasonic linear motor with fully laminated piezoelectric actuators.
Optical design of MOEMS-based micro-mechatronic modules for applications in spectroscopy
NASA Astrophysics Data System (ADS)
Tortschanoff, A.; Kremer, M.; Sandner, T.; Kenda, A.
2014-05-01
One of the important challenges for widespread application of MOEMS devices is to provide a modular interface for easy handling and accurate driving of the MOEMS elements, in order to enable seamless integration in larger spectroscopic system solutions. In this contribution we present in much detail the optical design of MOEMS driver modules comprising optical position sensing together with driver electronics, which can actively control different electrostatically driven MOEMS. Furthermore we will present concepts for compact spectroscopic devices, based on different MOEMS scanner modules with lD and 2D optical elements.
French Cooperative Passive Payload (FRECOPA)
NASA Technical Reports Server (NTRS)
Durin, Christian
1992-01-01
The fact that the LDEF satellite mission was extended resulted in a study of FRECOPA system elements. These tests were run on materials, electronics, wiring, and motor drives. It is worthwhile studying these elements as they have been exposed to the low earth orbit for nearly six years, whereas the experimental specimens were exposed for ten months. No functional damage was observed which was induced by impacts or erosion. A decrease in thermal, optical, and mechanical properties for DELRIN and teflon glass fabric induced by erosion and thermal environment was observed. The most important damage parameters are UV radiation and thermal cycling.
2013-01-01
Background Bacteria and archaea develop immunity against invading genomes by incorporating pieces of the invaders' sequences, called spacers, into a clustered regularly interspaced short palindromic repeats (CRISPR) locus between repeats, forming arrays of repeat-spacer units. When spacers are expressed, they direct CRISPR-associated (Cas) proteins to silence complementary invading DNA. In order to characterize the invaders of human microbiomes, we use spacers from CRISPR arrays that we had previously assembled from shotgun metagenomic datasets, and identify contigs that contain these spacers' targets. Results We discover 95,000 contigs that are putative invasive mobile genetic elements, some targeted by hundreds of CRISPR spacers. We find that oral sites in healthy human populations have a much greater variety of mobile genetic elements than stool samples. Mobile genetic elements carry genes encoding diverse functions: only 7% of the mobile genetic elements are similar to known phages or plasmids, although a much greater proportion contain phage- or plasmid-related genes. A small number of contigs share similarity with known integrative and conjugative elements, providing the first examples of CRISPR defenses against this class of element. We provide detailed analyses of a few large mobile genetic elements of various types, and a relative abundance analysis of mobile genetic elements and putative hosts, exploring the dynamic activities of mobile genetic elements in human microbiomes. A joint analysis of mobile genetic elements and CRISPRs shows that protospacer-adjacent motifs drive their interaction network; however, some CRISPR-Cas systems target mobile genetic elements lacking motifs. Conclusions We identify a large collection of invasive mobile genetic elements in human microbiomes, an important resource for further study of the interaction between the CRISPR-Cas immune system and invaders. PMID:23628424
Dynamic behavior of the mechanical systems from the structure of a hybrid automobile
NASA Astrophysics Data System (ADS)
Dinel, Popa; Irina, Tudor; Nicolae-Doru, Stănescu
2017-10-01
In introduction are presented solutions of planetary mechanisms that can be used in the construction of the hybrid automobiles where the thermal and electrical sources must be coupled. The systems have in their composition a planetary mechanism with two degrees of mobility at which are coupled a thermal engine, two revertible electrical machines, a gear transmission with four gears and a differential mechanism which transmits the motion at the driving wheels. For the study of the dynamical behavior, with numerical results, one designs such mechanisms, models the elements with solids in AutoCAD, and obtains the mechanical properties of the elements. Further on, we present and solve the equations of motion of a hybrid automotive for which one knows the dynamical parameters.
NASA Astrophysics Data System (ADS)
Carnebianca, C.; Pavesi, B.; Tuozzi, A.; Capone, R.
1986-06-01
The socioeconomic desirability in terms of market demand, technical economic feasibility, and price-performance for a Land Mobile Communication system ground based and/or satellite aided, able to satisfy the request of the traffic demand, foreseable in the 1995-2005 time frame, for the Western European countries was assessed. The criterion of economic value of the mobile system is considered as the driving element. The presence of gaps in the terrestrial system and reasonable traffic extrapolations suggest a very attractive role for a land mobile satellite communications mission.
Mobility scooter driving ability in visually impaired individuals.
Cordes, Christina; Heutink, Joost; Brookhuis, Karel A; Brouwer, Wiebo H; Melis-Dankers, Bart J M
2018-06-01
To investigate how well visually impaired individuals can learn to use mobility scooters and which parts of the driving task deserve special attention. A mobility scooter driving skill test was developed to compare driving skills (e.g. reverse driving, turning) between 48 visually impaired (very low visual acuity = 14, low visual acuity = 10, peripheral field defects = 11, multiple visual impairments = 13) and 37 normal-sighted controls without any prior experience with mobility scooters. Performance on this test was rated on a three-point scale. Furthermore, the number of extra repetitions on the different elements were noted. Results showed that visually impaired participants were able to gain sufficient driving skills to be able to use mobility scooters. Participants with visual field defects combined with low visual acuity showed most problems learning different skills and needed more training. Reverse driving and stopping seemed to be most difficult. The present findings suggest that visually impaired individuals are able to learn to drive mobility scooters. Mobility scooter allocators should be aware that these individuals might need more training on certain elements of the driving task. Implications for rehabilitation Visual impairments do not necessarily lead to an inability to acquire mobility scooter driving skills. Individuals with peripheral field defects (especially in combination with reduced visual acuity) need more driving ability training compared to normal-sighted people - especially to accomplish reversing. Individual assessment of visually impaired people is recommended, since participants in this study showed a wide variation in ability to learn driving a mobility scooter.
NASA Astrophysics Data System (ADS)
Carnebianca, C.; Pavesi, B.; Tuozzi, A.; Capone, R.
1986-06-01
The socioeconomic desirability in terms of market demand, technical economic feasibility, and price-performance for a Land Mobile Communication system ground based and/or satellite aided, able to satisfy the request of the traffic demand, foreseeable in the 1995 to 2005 time frame, for the Western European countries was assessed. The criterion of economic value of the mobile system is considered as the driving element. Data on traffic; socioeconomic factors; economic factors; and radiotelephony, paging, and dispatch subscription and value for money trends are presented.
COLD CATHODE DECADE TUBES AS ADDRESS ELEMENTS & CHANNEL STORES IN MULTICHANNEL ANALYZER SYSTEMS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Parwardhan, P.K.; Phadnis, M.G.
1963-07-01
ABS>The application of dekatron tubes in address logic and channel stores in multichannel analyzer systems is considered, and circuits for dekatron drive developed for this purpose are discussed. The glow dynamics in such circuits is explained on the basis of the new concept of alpha and beta transfers. A brief account of the design and performance (bringing out the effect of certain parameters on overall performance) of an integrated 100-channel analyzer system, which incorporates the new circuits, is also included. (auth)
Ultrasonic phased array controller for hyperthermia applications.
Benkeser, P J; Pao, T L; Yoon, Y J
1991-01-01
Multiple and mechanically scanned ultrasound transducer systems have demonstrated the efficacy of using ultrasound to produce deep localized hyperthermia. The use of ultrasonic phased arrays has been proposed as an alternative to these systems. A phased array offers a more flexible approach to heating tumours in that the size, shape, and position of its focal region can be altered during the course of treatment in order to achieve the desired temperature distribution. This added flexibility comes at the cost of increased complexity of the hardware necessary to drive the transducer because each element requires its own amplifer with both phase and amplitude control. In order for phased arrays with large numbers of elements to be feasible for hyperthermia applications, the complexity of this circuitry must be minimized. This paper describes a circuit design which simplifies the electronics required to control a phased array transducer system for hyperthermia applications. The design is capable of controlling virtually any type of phased array transducer operating at frequencies less than 2 MHz. The system performance was verified through beam profile measurements using a 48-element tapered phased array transducer.
Finite element analysis of ROPS for mechanical driving dump truck cab
NASA Astrophysics Data System (ADS)
Wang, Yong; Xie, Heping; Fang, Yuanbin; Feng, Handui; Dong, Lei
2018-02-01
For roll-over protective structures (ROPS) in a mechanical driving dump truck cab, it simulates the lateral, vertical and longitudinal loads of ROPS. It obtains stress and deformation of the cab that occurs to roll. For the relative weak position of ROPS in the cab, the structure of the cab is improved and verified according to the ISO 3164: 1995. The results show that the established finite element model can effectively predict the deformation and stress distribution of ROPS, and optimize the weak structure of the cab, which has important guiding significance for structural design of the cab and ROPS optimization of the mechanical driving dump truck cab.
NASA Astrophysics Data System (ADS)
Pavlov, S. S.; Dmitriev, A. Yu.; Chepurchenko, I. A.; Frontasyeva, M. V.
2014-11-01
The automation system for measurement of induced activity of gamma-ray spectra for multi-element high volume neutron activation analysis (NAA) was designed, developed and implemented at the reactor IBR-2 at the Frank Laboratory of Neutron Physics. The system consists of three devices of automatic sample changers for three Canberra HPGe detector-based gamma spectrometry systems. Each sample changer consists of two-axis of linear positioning module M202A by DriveSet company and disk with 45 slots for containers with samples. Control of automatic sample changer is performed by the Xemo S360U controller by Systec company. Positioning accuracy can reach 0.1 mm. Special software performs automatic changing of samples and measurement of gamma spectra at constant interaction with the NAA database.
Heckman, T.P.
1961-05-01
A nuclear power reactor of the type in which a liquid moderator-coolant is transformed by nuclear heating into a vapor that may be used to drive a turbo- generator is described. The core of this reactor comprises a plurality of freely suspended tubular fuel elements, called fuel element trains, within which nonboiling pressurized liquid moderator-coolant is preheated and sprayed through orifices in the walls of the trains against the outer walls thereof to be converted into vapor. Passage of the vapor ovcr other unwetted portions of the outside of the fuel elements causes the steam to be superheated. The moderatorcoolant within the fuel elements remains in the liqUid state, and that between the fuel elements remains substantiaily in the vapor state. A unique liquid neutron-absorber control system is used. Advantages expected from the reactor design include reduced fuel element failure, increased stability of operation, direct response to power demand, and circulation of a minimum amount of liquid moderatorcoolant. (A.G.W.)
1978-07-01
horizontally mounted, single-end suction, single- stage centrifugal pumps. The rotating elements are mounted on the shaft of the driving motor, and the pump...annual open-and-inspect requirement for MIP E-17/296-21, MRC 21 A14V A. Industrial Facility Improvements -- None IMA Improvements -- None Intergrated ...Circulating Pump, Warren Pumps, Inc., NAVSHIPS 347-3146, January 1959. 4. Technical Manual - Horizontal Close-Co!;pled Pumps Sea (Salt) Water
1981-05-01
made to provide mounting bosses for the closed loop conveyor chute . Ten small round bosses were welded onto the housing to provide this support...became necessary to depart from previous closed loop feeder designs . The original feed system consisted of a series of conveyor elements in a flexible...The flexible chuting has been replaced with rigid chuting forming a loop around the gun housing. This design affords the maximum stiffness and hence
Integrated orbital servicing study follow-on. Volume 3: Engineering test unit and controls
NASA Technical Reports Server (NTRS)
1978-01-01
A one-g servicing demonstration system which can be used to investigate and develop, in a real time hands-on situation, a wide variety of the mechanism and control system aspects of orbital servicing in the form of module exchange is described including the engineering test unit and the servicer servo drive console. A series of recommendations for future work is given concerning the control problem and more efficient module exchanges, mechanical elements, and electronics.
An iterative requirements specification procedure for decision support systems.
Brookes, C H
1987-08-01
Requirements specification is a key element in a DSS development project because it not only determines what is to be done, it also drives the evolution process. A procedure for requirements elicitation is described that is based on the decomposition of the DSS design task into a number of functions, subfunctions, and operators. It is postulated that the procedure facilitates the building of a DSS that is complete and integrates MIS, modelling and expert system components. Some examples given are drawn from the health administration field.
Computer memory power control for the Galileo spacecraft
NASA Technical Reports Server (NTRS)
Detwiler, R. C.
1983-01-01
The developmental history, major design drives, and final topology of the computer memory power system on the Galileo spacecraft are described. A unique method of generating memory backup power directly from the fault current drawn during a spacecraft power overload or fault condition allows this system to provide continuous memory power. This concept provides a unique solution to the problem of volatile memory loss without the use of a battery of other large energy storage elements usually associated with uninterrupted power supply designs.
NASA Astrophysics Data System (ADS)
Fiege, A.; Ruprecht, P.; Simon, A. C.; Holtz, F.
2017-12-01
Mafic magma recharge is a common process that triggers physical and chemical mixing in magmatic systems and drives their evolution, resulting in, e.g., hybridization and volcanic eruptions. Once magma-magma contact is initiated, rapid heat-flux commonly leads to the formation of a cooling-induced crystal mush on the mafic side of the interface. Here, on a local scale (µm to cm), at the magma-magma interface, melt-melt diffusive exchange is required to approach equilibrium. Significant chemical potential gradients drive a complex, multi-element mass flux between the two systems (Liang, 2010). This diffusive-equilibration often controls crystal dissolution rates within the boundary layers and, thus, the formation of interconnected melt or fluid networks. Such networks provide important pathways for the transport of volatiles and trace metals from the mafic recharge magma to the felsic host magma, where the latter may feed volcanic activities and ore deposits. While major element diffusion in silicate melts is mostly well understood, even in complex systems, the available data for many trace element metals are limited (Liang, 2010; Zhang et al., 2010). Differences in diffusivity in a dynamic, mixing environment can cause trace element fractionation, in particular during crystallization and volatile exsolution and separation. This may affect trace element signatures in phenocrysts and magmatic volatile phases that can form near a magma-magma boundary. As a result, the chemistry of volcanic gases and magmatic-hydrothermal ore deposits may be partially controlled by such mixing phenomena. We performed melt-melt diffusion-couple experiments at 150 MPa, 1100°C, FMQ, FMQ+1 and FMQ+3 (FMQ: fayalite-magnetite-quartz oxygen fugacity buffer). Hydrated, sulfur-bearing cylinders of dacite and basaltic andesite were equilibrated for up to 20 h. Major and trace element gradients were measured by using laser-ablation ICP-MS and electron microprobe analyses. The results we will present will help to fill data gaps for the diffusivity of certain metals in silicate melts (e.g., V, Mo, W). First data analyses indicate a higher diffusivity of V when compared to W . Liang (2010) Rev Mineral Geochem 72, 409-446; Zhang et al. (2010) Rev Mineral Geochem 72, 311-408.
Data that drive: Closing the loop in the learning hospital system.
Liu, Vincent X; Morehouse, John W; Baker, Jennifer M; Greene, John D; Kipnis, Patricia; Escobar, Gabriel J
2016-11-01
The learning healthcare system describes a vision of US healthcare that capitalizes on science, information technology, incentives, and care culture to drive improvements in the quality of health care. The inpatient setting, one of the most costly and impactful domains of healthcare, is an ideal setting in which to use data and information technology to foster continuous learning and quality improvement. The rapid digitization of inpatient medicine offers incredible new opportunities to use data from routine care to generate new discovery and thus close the virtuous cycle of learning. We use an object lesson-sepsis care within the 21 hospitals of the Kaiser Permanente Northern California integrated healthcare delivery system-to offer insight into the critical elements necessary for developing a learning hospital system. We then describe how a hospital-wide data-driven approach to inpatient care can facilitate improvements in the quality of hospital care. Journal of Hospital Medicine 2016;11:S11-S17. © 2016 Society of Hospital Medicine. © 2016 Society of Hospital Medicine.
Descriptive analysis of combine cabin vibrations and their effect on the human body
NASA Astrophysics Data System (ADS)
Hostens, I.; Ramon, H.
2003-09-01
All on- and off-road vehicles are exposed to vibrations caused by unevenness of road or soil profile, moving elements within the machine or implements. A higher prevalence of low back pain is found in drivers of off-road machinery than in other drivers. In this study, significantly higher levels of low-frequency vibrations are found in the cabin of a combine, driving at high speed (20 km/h) on a concrete surface, compared to driving slower on field road. Comfort values indicate that injury can result from long-term driving on the field as well as on a concrete road. As seats with suspension systems are the main transmission paths of vibration towards the spine of the driver, their vibration attenuating characteristics play an important role in comfort assessment. The resonant frequency of seats with passive suspension system, used in agricultural machinery, lies in the low-frequency range most excited in agricultural machinery. A seat with air suspension is found to attenuate better frequencies above 4 Hz and provide more comfort to the driver than a seat with a mechanical suspension.
Visualizing the spinal neuronal dynamics of locomotion
NASA Astrophysics Data System (ADS)
Subramanian, Kalpathi R.; Bashor, D. P.; Miller, M. T.; Foster, J. A.
2004-06-01
Modern imaging and simulation techniques have enhanced system-level understanding of neural function. In this article, we present an application of interactive visualization to understanding neuronal dynamics causing locomotion of a single hip joint, based on pattern generator output of the spinal cord. Our earlier work visualized cell-level responses of multiple neuronal populations. However, the spatial relationships were abstract, making communication with colleagues difficult. We propose two approaches to overcome this: (1) building a 3D anatomical model of the spinal cord with neurons distributed inside, animated by the simulation and (2) adding limb movements predicted by neuronal activity. The new system was tested using a cat walking central pattern generator driving a pair of opposed spinal motoneuron pools. Output of opposing motoneuron pools was combined into a single metric, called "Net Neural Drive", which generated angular limb movement in proportion to its magnitude. Net neural drive constitutes a new description of limb movement control. The combination of spatial and temporal information in the visualizations elegantly conveys the neural activity of the output elements (motoneurons), as well as the resulting movement. The new system encompasses five biological levels of organization from ion channels to observed behavior. The system is easily scalable, and provides an efficient interactive platform for rapid hypothesis testing.
A new assessment model and tool for pediatric nurse practitioners.
Burns, C
1992-01-01
This article presents a comprehensive assessment model for pediatric nurse practitioner (PNP) practice that integrates familiar elements of the classical medical history, Gordon's Functional Health Patterns, and developmental fields into one system. This model drives the diagnostic reasoning process toward consideration of a broad range of disease, daily living (nursing diagnosis), and developmental diagnoses, which represents PNP practice better than the medical model does.
The non-steady state growth of pearlite outside the Hultgren extrapolation
Martin-Aranda, Maria; Rementeria, Rosalia; Hackenberg, Robert Errol; ...
2016-12-14
Here, the goal of this paper is to analyse the effect of adding Al on the non-steady pearlite growth occurring in a Fe–C–Mn system. The results are discussed in terms of the partitioning of elements across the austenite/ferrite and austenite/cementite interfaces, and the modification of the pearlite driving force related to the change in carbon activity in austenite.
Assessment of Wearable Sensor Technologies for Biosurveillance
2014-11-01
used in the field. By building devices that leverage elements such as more efficient operating systems and lower power requirements, developers may...technology into the hands of nearly every citizen. Mid-term forecasts for this sector anticipate the development and approval of more precise medical...Batteries with different shapes Paper USB intelliPaper A “smart” paper business card bearing a detachable paper USB drive Deep Tissue Power
Integration of the virtual 3D model of a control system with the virtual controller
NASA Astrophysics Data System (ADS)
Herbuś, K.; Ociepka, P.
2015-11-01
Nowadays the design process includes simulation analysis of different components of a constructed object. It involves the need for integration of different virtual object to simulate the whole investigated technical system. The paper presents the issues related to the integration of a virtual 3D model of a chosen control system of with a virtual controller. The goal of integration is to verify the operation of an adopted object of in accordance with the established control program. The object of the simulation work is the drive system of a tunneling machine for trenchless work. In the first stage of work was created an interactive visualization of functioning of the 3D virtual model of a tunneling machine. For this purpose, the software of the VR (Virtual Reality) class was applied. In the elaborated interactive application were created adequate procedures allowing controlling the drive system of a translatory motion, a rotary motion and the drive system of a manipulator. Additionally was created the procedure of turning on and off the output crushing head, mounted on the last element of the manipulator. In the elaborated interactive application have been established procedures for receiving input data from external software, on the basis of the dynamic data exchange (DDE), which allow controlling actuators of particular control systems of the considered machine. In the next stage of work, the program on a virtual driver, in the ladder diagram (LD) language, was created. The control program was developed on the basis of the adopted work cycle of the tunneling machine. The element integrating the virtual model of the tunneling machine for trenchless work with the virtual controller is the application written in a high level language (Visual Basic). In the developed application was created procedures responsible for collecting data from the running, in a simulation mode, virtual controller and transferring them to the interactive application, in which is verified the operation of the adopted research object. The carried out work allowed foot the integration of the virtual model of the control system of the tunneling machine with the virtual controller, enabling the verification of its operation.
Semiconductor quantum well irradiated by a two-mode electromagnetic field as a terahertz emitter
NASA Astrophysics Data System (ADS)
Mandal, S.; Liew, T. C. H.; Kibis, O. V.
2018-04-01
We study theoretically the nonlinear optical properties of a semiconductor quantum well (QW) irradiated by a two-mode electromagnetic wave consisting of a strong resonant dressing field and a weak off-resonant driving field. In the considered strongly coupled electron-field system, the dressing field opens dynamic Stark gaps in the electron energy spectrum of the QW, whereas the driving field induces electron oscillations in the QW plane. Since the gapped electron spectrum restricts the amplitude of the oscillations, the emission of a frequency comb from the QW appears. Therefore, the doubly driven QW operates as a nonlinear optical element which can be used, particularly, for optically controlled generation of terahertz radiation.
Addiction is a Reward Deficit and Stress Surfeit Disorder
Koob, George F.
2013-01-01
Drug addiction can be defined by a three-stage cycle – binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation – that involves allostatic changes in the brain reward and stress systems. Two primary sources of reinforcement, positive and negative reinforcement, have been hypothesized to play a role in this allostatic process. The negative emotional state that drives negative reinforcement is hypothesized to derive from dysregulation of key neurochemical elements involved in the brain reward and stress systems. Specific neurochemical elements in these structures include not only decreases in reward system function (within-system opponent processes) but also recruitment of the brain stress systems mediated by corticotropin-releasing factor (CRF) and dynorphin-κ opioid systems in the ventral striatum, extended amygdala, and frontal cortex (both between-system opponent processes). CRF antagonists block anxiety-like responses associated with withdrawal, block increases in reward thresholds produced by withdrawal from drugs of abuse, and block compulsive-like drug taking during extended access. Excessive drug taking also engages the activation of CRF in the medial prefrontal cortex, paralleled by deficits in executive function that may facilitate the transition to compulsive-like responding. Neuropeptide Y, a powerful anti-stress neurotransmitter, has a profile of action on compulsive-like responding for ethanol similar to a CRF1 antagonist. Blockade of the κ opioid system can also block dysphoric-like effects associated with withdrawal from drugs of abuse and block the development of compulsive-like responding during extended access to drugs of abuse, suggesting another powerful brain stress system that contributes to compulsive drug seeking. The loss of reward function and recruitment of brain systems provide a powerful neurochemical basis that drives the compulsivity of addiction. PMID:23914176
Design, modeling and control of a novel multi functional translational-rotary micro ultrasonic motor
NASA Astrophysics Data System (ADS)
Tuncdemir, Safakcan
The major goal of this thesis was to design and develop an actuator, which is capable of producing translational and rotary output motions in a compact structure with simple driving conditions, for the needs of small-scale actuators for micro robotic systems. Piezoelectric ultrasonic motors were selected as the target actuator schemes because of their unbeatable characteristics in the meso-scale range, which covers the structure sizes from hundred micrometers to ten millimeters and with operating ranges from few nanometers to centimeters. In order to meet the objectives and the design constraints, a number of key research tasks had to be undertaken. The design constraints and objectives were so stringent and entangled that none of the existing methods in literature could solve the research problems individually. Therefore, several unique methods were established to accomplish the research objectives. The methods produced novel solutions at every stage of design, development and modeling of the multi functional micro ultrasonic motor. Specifically, an ultrasonic motor utilizing slanted ceramics on a brass rod was designed. Because of the unique slanted ceramics design, longitudinal and torsional mode vibration modes could be obtained on the same structure. A ring shaped mobile element was loosely fitted on the metal rod stator. The mobile element moved in translational or rotational, depending on whether the vibration mode was longitudinal or torsional. A new ultrasonic motor drive method was required because none of the existing ultrasonic motor drive techniques were able to provide both output modes in a compact and cylindrical structure with the use of single drive source. By making use of rectangular wave drive signals, saw-tooth shaped displacement profile could be obtained at longitudinal and torsional resonance modes. Thus, inheriting the operating principle of smooth impact drive method, a new resonance type inertial drive was introduced. This new technique combines the advantages of inertial method with resonance drive. The motor that combines inertial drive at resonance will be a new type of ultrasonic motor, according to the classification of vibration types. A method to analyze the stator vibration by incorporating the piezoelectric loss coefficients was developed. By using the model, natural frequencies of the operating modes were predicted and exact formulations of the vibration displacements in longitudinal and torsional modes were obtained. The vibration model was in perfect agreement with the ATILA finite element analysis simulations even for different design parameters. The model was also used in design optimization and for theoretical explanation of the newly introduced motor drive technique. The theoretical analysis of the operating principle was verified with finite element analysis simulations and by vibration measurements. Several prototypes of motor were built in order to realize the dual function output as the main objective of this research. Translational output was observed for rectangular wave input signals at the resonance frequency of the fundamental longitudinal mode.The output mode changed to the rotational mode when the operating frequency switched for the fundamental torsional mode. While the mode of motor could be switched by switching the operating frequency, the direction of motion could be reversed by switching the duty cycle of rectangular input signals from D % to (100-D) %. A prototype (5 mm diameter, 25 mm total length produced 55 mm/s (translational) and 3 rad/s (rotary) speed under 40 mN blocking force, when the input signal was 40 V pp rectangular with 33% duty cycle. The motor speed at translational mode was characterized for different input voltage and output force. The meso-scale ultrasonic motor which utilizes smooth impact drive method, provided a unique ability to produce dual function with prominent output characteristics in a compact structure by using simple drive conditions.
The impact of various distance between axes of worm gear on torque value. Worm gear test stand
NASA Astrophysics Data System (ADS)
Sobek, M.; Baier, A.; Grabowski, Ł.
2017-08-01
Transferring both rotational and translational movements in systems used in the automotive industry is a very important and complex issue. In addition, the situation becomes much more difficult and complicated when the design of the transition system requires a high precision of operation as well as a well definite and long operating life. Such requirements are imposed on all components of today’s motor vehicles. However, particular attention is paid to the elements that directly or indirectly affect the safety of persons traveling in the vehicle. Such components are undoubtedly components included as parts of the steering system of the vehicle. Power steering systems have been present in motor vehicles for more than a century. They go through continuous metamorphosis and they are getting better and better. Current power steering systems are based on an electric motor and some kind of transmission. Depending on the position of the drive relative to the steering column, different configurations of the transmission are used. This article will cover issues related to tests of power steering gearing using a worm drive. The worm drive is a very specific example of a propulsion system that uses twisted axles. Normally, in this type of transition you can find two gear units with the axis mounted with a 90° angle between. The components of the worm drive are a worm and a worm gear, also called a worm wheel. In terms of the geometrical form, the worm resembles a helical spur gear. The shape of the worm is similar to the shape of a screw with a trapezoidal thread. A correct matching of these two components ensures proper operation of the entire transmission. Incorrect positioning of the components in relation to each other can significantly reduce the lifetime of the drive unit, and also lead to abnormal work, eg by raising the noise level. This article describes a test method of finding the appropriate distance between the axles of both worm drive units by testing the torque change during gear operation.
Integrative and conjugative elements and their hosts: composition, distribution and organization
Touchon, Marie; Rocha, Eduardo P. C.
2017-01-01
Abstract Conjugation of single-stranded DNA drives horizontal gene transfer between bacteria and was widely studied in conjugative plasmids. The organization and function of integrative and conjugative elements (ICE), even if they are more abundant, was only studied in a few model systems. Comparative genomics of ICE has been precluded by the difficulty in finding and delimiting these elements. Here, we present the results of a method that circumvents these problems by requiring only the identification of the conjugation genes and the species’ pan-genome. We delimited 200 ICEs and this allowed the first large-scale characterization of these elements. We quantified the presence in ICEs of a wide set of functions associated with the biology of mobile genetic elements, including some that are typically associated with plasmids, such as partition and replication. Protein sequence similarity networks and phylogenetic analyses revealed that ICEs are structured in functional modules. Integrases and conjugation systems have different evolutionary histories, even if the gene repertoires of ICEs can be grouped in function of conjugation types. Our characterization of the composition and organization of ICEs paves the way for future functional and evolutionary analyses of their cargo genes, composed of a majority of unknown function genes. PMID:28911112
2002 traffic crash facts annual report
DOT National Transportation Integrated Search
2002-01-01
Driving is inherently dangerous. Further, driving is a function of three related, : but independent, elements: the driver, the vehicle and the roadway. As : reflected in these Traffic Crash Facts, most crashes are the result of : improper drivi...
NASA Astrophysics Data System (ADS)
Thompson, T. B.; Meade, B. J.
2015-12-01
The Himalayas are the tallest mountains on Earth with ten peaks exceeding 8000 meters, including Mt. Everest. The geometrically complex fault system at the Himalayan Range Front produces both great relief and great earthquakes, like the recent Mw=7.8 Nepal rupture. Here, we develop geometrically accurate elastic boundary element models of the fault system at the Himalayan Range Front including the Main Central Thrust, South Tibetan Detachment, Main Frontal Thrust, Main Boundary Thrust, the basal detachment, and surface topography. Using these models, we constrain the tectonic driving forces and frictional fault strength required to explain Quaternary fault slip rate estimates. These models provide a characterization of the heterogeneity of internal stress in the region surrounding the 2015 Nepal earthquake.
Implementation of a self-controlling heater
NASA Technical Reports Server (NTRS)
Strange, M. G.
1973-01-01
Temperature control of radiation sensors, targets, and other critical components is a common requirement in modern scientific instruments. Conventional control systems use a heater and a temperature sensor mounted on the body to be controlled. For proportional control, the sensor provides feedback to circuitry which drives the heater with an amount of power proportional to the temperature error. It is impractical or undesirable to mount both a heater and a sensor on certain components such as ultra-small parts or thin filaments. In principle, a variable current through the element is used for heating, and the change in voltage drop due to the element's temperature coefficient is separated and used to monitor or control its own temperature. Since there are no thermal propagation delays between heater and sensor, such control systems are exceptionally stable.
A Hybrid Converter for Improving Light Load Efficiency
NASA Astrophysics Data System (ADS)
Takahashi, Masaya; Nishijima, Kimihiro; Nagao, Michihiko; Sato, Terukazu; Nabeshima, Takashi
In order to reduce power consumption of electronic equipment in stand-by mode, idle-mode and sleep-mode, a simple efficiency improvement technique for switching regulator in light load region is proposed. In this technique, under the light load, the small switching elements in a MOSFET driver circuit are used instead of the switching elements in a main regulator circuit to reduce driving losses. Of course, under the load heavier than light load, the MOSFET driver drives the switching elements in the main regulator circuit. The efficiency of a 2.5V/5A prototype buck converter is improved from 47.1% to 72.7% by using the proposed technique.
NASA Astrophysics Data System (ADS)
Mr., J. Ravi Kumar; Banakara, Basavaraja, Dr.
2017-08-01
This paper presents electromagnetic and thermal behavior of Induction Motor (IM) through the modeling and analysis by applying multiphysics coupled Finite Element Analysis (FEA). Therefore prediction of the magnetic flux, electromagnetic torque, stator and rotor losses and temperature distribution inside an operating electric motor are the most important issues during its design. Prediction and estimation of these parameters allows design engineers to decide capability of the machine for the proposed load, temperature rating and its application for which it is being designed ensuring normal motor operation at rated conditions. In this work, multiphysics coupled electromagnetic - thermal modeling and analysis of induction motor at rated and high frequency has carried out applying Arkkio’s torque method. COMSOL Multiphysics software is used for modeling and finite element analysis of IM. Transient electromagnetic torque, magnetic field distribution, speed-torque characteristics of IM were plotted and studied at different frequencies. This proposed work helps in the design and prediction of accurate performance of induction motor specific to various industrial drive applications. Results obtained are also validated with experimental analysis. The main purpose of this model is to use it as an integral part of the design aiming to system optimization of Variable Speed Drive (VSD) and its components using coupled simulations.
NASA Astrophysics Data System (ADS)
Abadjieva, Emilia; Abadjiev, Valentin
2017-09-01
This work is developed on the basis of the illustrated main parts of the kinematic theory (theory of gearing) of the spatial rack drives in Part 1 of this study. The applied theoretical approach to their synthesis, based on the T. Olivier's second principle is defined. A study of the geometric nature of the surface of action (mesh region, respectively) of these class transmissions is shown. Research software programs for synthesis and visualization of these transmissions and their specific elements are elaborated, on the basis of the given algorithms to the synthesis of the elements of high kinematic joints (active tooth surfaces), with which the movable links of the studied gear systems are equipped.
A sex-ratio meiotic drive system in Drosophila simulans. II: an X-linked distorter.
Tao, Yun; Araripe, Luciana; Kingan, Sarah B; Ke, Yeyan; Xiao, Hailian; Hartl, Daniel L
2007-11-06
The evolution of heteromorphic sex chromosomes creates a genetic condition favoring the invasion of sex-ratio meiotic drive elements, resulting in the biased transmission of one sex chromosome over the other, in violation of Mendel's first law. The molecular mechanisms of sex-ratio meiotic drive may therefore help us to understand the evolutionary forces shaping the meiotic behavior of the sex chromosomes. Here we characterize a sex-ratio distorter on the X chromosome (Dox) in Drosophila simulans by genetic and molecular means. Intriguingly, Dox has very limited coding capacity. It evolved from another X-linked gene, which also evolved de nova. Through retrotransposition, Dox also gave rise to an autosomal suppressor, not much yang (Nmy). An RNA interference mechanism seems to be involved in the suppression of the Dox distorter by the Nmy suppressor. Double mutant males of the genotype dox; nmy are normal for both sex-ratio and spermatogenesis. We postulate that recurrent bouts of sex-ratio meiotic drive and its subsequent suppression might underlie several common features observed in the heterogametic sex, including meiotic sex chromosome inactivation and achiasmy.
ERIC Educational Resources Information Center
Partnership for 21st Century Skills, 2011
2011-01-01
Standards drive critical elements of the American educational system--the curricula that schools follow, the textbooks students read, and the tests they take. Similarly, standards establish the levels of performance that students, teachers and schools are expected to meet. To succeed in the 21st century, all students will need to perform to high…
An Annotated Bibliography of the Manned Systems Measurement Literature
1985-02-01
designs that are considered applicable to assessment of training effectiveness include the classic Solomon four - group design; iterative adaptation to...element (analogue computer) were used for this study . *».U Operators were taken from 3 groups : (1) persons with both licensed flying and driving...conclusions are that the classic four - group design is impractical for most training evaluation; that "adaptive research for big effects" is apt to be
Basu, Abhijit; Jain, Niyati; Tolbert, Blanton S.; Komar, Anton A.
2017-01-01
Abstract RNA–protein interactions with physiological outcomes usually rely on conserved sequences within the RNA element. By contrast, activity of the diverse gamma-interferon-activated inhibitor of translation (GAIT)-elements relies on the conserved RNA folding motifs rather than the conserved sequence motifs. These elements drive the translational silencing of a group of chemokine (CC/CXC) and chemokine receptor (CCR) mRNAs, thereby helping to resolve physiological inflammation. Despite sequence dissimilarity, these RNA elements adopt common secondary structures (as revealed by 2D-1H NMR spectroscopy), providing a basis for their interaction with the RNA-binding GAIT complex. However, many of these elements (e.g. those derived from CCL22, CXCL13, CCR4 and ceruloplasmin (Cp) mRNAs) have substantially different affinities for GAIT complex binding. Toeprinting analysis shows that different positions within the overall conserved GAIT element structure contribute to differential affinities of the GAIT protein complex towards the elements. Thus, heterogeneity of GAIT elements may provide hierarchical fine-tuning of the resolution of inflammation. PMID:29069516
Modeling and analysis of the DSS-14 antenna control system
NASA Technical Reports Server (NTRS)
Gawronski, W.; Bartos, R.
1996-01-01
An improvement of pointing precision of the DSS-14 antenna is planned for the near future. In order to analyze the improvement limits and to design new controllers, a precise model of the antenna and the servo is developed, including a finite element model of the antenna structure and detailed models of the hydraulic drives and electronic parts. The DSS-14 antenna control system has two modes of operation: computer mode and precision mode. The principal goal of this investigation is to develop the model of the computer mode and to evaluate its performance. The DSS-14 antenna computer model consists of the antenna structure and drives in azimuth and elevation. For this model, the position servo loop is derived, and simulations of the closed-loop antenna dynamics are presented. The model is significantly different from that for the 34-m beam-waveguide antennas.
Ambulatory Healthcare Utilization in the United States: A System Dynamics Approach
NASA Technical Reports Server (NTRS)
Diaz, Rafael; Behr, Joshua G.; Tulpule, Mandar
2011-01-01
Ambulatory health care needs within the United States are served by a wide range of hospitals, clinics, and private practices. The Emergency Department (ED) functions as an important point of supply for ambulatory healthcare services. Growth in our aging populations as well as changes stemming from broader healthcare reform are expected to continue trend in congestion and increasing demand for ED services. While congestion is, in part, a manifestation of unmatched demand, the state of the alignment between the demand for, and supply of, emergency department services affects quality of care and profitability. The central focus of this research is to provide an explanation of the salient factors at play within the dynamic demand-supply tensions within which ambulatory care is provided within an Emergency Department. A System Dynamics (SO) simulation model is used to capture the complexities among the intricate balance and conditional effects at play within the demand-supply emergency department environment. Conceptual clarification of the forces driving the elements within the system , quantifying these elements, and empirically capturing the interaction among these elements provides actionable knowledge for operational and strategic decision-making.
[Analysis of surface composition of three-way catalysts of in-use vehicles].
Xie, Shu-xia; Hu, Jing-nan; Bao, Xiao-feng; Zhang, Ke-song; Li, Zhen-hua; Wang, Hai-tao
2010-07-01
The kinds and contents of surface elements in three-way catalysts of six light-duty in-use taxi cabs, which were mainly operated in Beijing and whose driving mileages were in the range of 34 x 10(4)-59 x 10(4) km, were determined by X-ray fluorescence spectrometry (XRF), and the effect of driving mileage on element content was investigated. Results showed that nearly 30 kinds of elements were present on the catalyst surface. The main elements of different samples were similar. The common elements of the pollutant on the front and rear catalysts were P, Ca, Zn and Mn etc., most of which are from engine oil and gasoline. S was only observed on the rear catalysts, indicating that S tends to deposit on the rear catalysts. After 34 x 10(4) km run, the P content increased very slowly and 40 x 10(4) km run S content reached a saturated value. While the contents of Ca, Zn and Mn still exhibit an increase tendency after 56 x 10(4) km. That means after 40 x 10(4) km driving mileage, the effects of P and S on the catalyst activity are minor, and the continuous deposit of Ca, Zn and Mn will lead to further decrease of the activity.
Transportation systems analyses: Volume 1: Executive Summary
NASA Astrophysics Data System (ADS)
1993-05-01
The principal objective of this study is to accomplish a systems engineering assessment of the nation's space transportation infrastructure. This analysis addresses the necessary elements to perform man delivery and return, cargo transfer, cargo delivery, payload servicing, and the exploration of the Moon and Mars. Specific elements analyzed, but not limited to, include the Space Exploration Initiative (SEI), the National Launch System (NLS), the current expendable launch vehicle (ELV) fleet, ground facilities, the Space Station Freedom (SSF), and other civil, military and commercial payloads. The performance of this study entails maintaining a broad perspective on the large number of transportation elements that could potentially comprise the U.S. space infrastructure over the next several decades. To perform this systems evaluation, top-level trade studies are conducted to enhance our understanding of the relationships between elements of the infrastructure. This broad 'infrastructure-level perspective' permits the identification of preferred infrastructures. Sensitivity analyses are performed to assure the credibility and usefulness of study results. This executive summary of the transportation systems analyses (TSM) semi-annual report addresses the SSF logistics resupply. Our analysis parallels the ongoing NASA SSF redesign effort. Therefore, there could be no SSF design to drive our logistics analysis. Consequently, the analysis attempted to bound the reasonable SSF design possibilities (and the subsequent transportation implications). No other strategy really exists until after a final decision is rendered on the SSF configuration.
High-Power Actuation from Molecular Photoswitches in Enantiomerically Paired Soft Springs.
Aßhoff, Sarah J; Lancia, Federico; Iamsaard, Supitchaya; Matt, Benjamin; Kudernac, Tibor; Fletcher, Stephen P; Katsonis, Nathalie
2017-03-13
Motion in plants often relies on dynamic helical systems as seen in coiling tendrils, spasmoneme springs, and the opening of chiral seedpods. Developing nanotechnology that would allow molecular-level phenomena to drive such movements in artificial systems remains a scientific challenge. Herein, we describe a soft device that uses nanoscale information to mimic seedpod opening. The system exploits a fundamental mechanism of stimuli-responsive deformation in plants, namely that inflexible elements with specific orientations are integrated into a stimuli-responsive matrix. The device is operated by isomerization of a light-responsive molecular switch that drives the twisting of strips of liquid-crystal elastomers. The strips twist in opposite directions and work against each other until the pod pops open from stress. This mechanism allows the photoisomerization of molecular switches to stimulate rapid shape changes at the macroscale and thus to maximize actuation power. © 2017 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.
From Geodynamics to Simplicity
NASA Astrophysics Data System (ADS)
Anderson, D. L.
2002-12-01
Mantle convection and plate tectonics are often thought as synonymous. Convection is sometimes treated as the driver or plate tectonics is viewed as simply a manifestation of mantle convection. Mantle plumes are regarded as supplying some of the elements missing in the plate tectonic and mantle convection paradigms, such as island chains, swells and large igneous provinces. An alternate view is motivated by Prigogine's concept of far-from-equilibrium self-organization ( SOFFE), not to be confused with Bak's self-organized criticality ( SOC) . In a SOFFE system the components interact, and the system is small compared to the outside world to which it is open. There must be multiple possible states and dissipation is important. Such a system is sensitive to small changes. Rayleigh-Benard convection in a container with isothermal walls is such a self-organizing system ; the driving bouyancy and the dissipation ( viscosity ) are in the fluid. In Marangoni convection the driving forces ( surface tension ) and dissipation are in the surface film and this organizes the surface and the underlying fluid. The mantle provides energy and matter to the interacting plate system but forces in the plates drive and dissipate the energy. Thus, plate tectonics may be a SOFFEE system that drives convection,as are systems cooled from above, in general. If so, plates will reorganize as boundary conditions change ; incipient plate boundaries will emerge as volcanic chains at tensile regions. Plates are defined as regions of lateral compression ( force chains ), rather than strength, and they are ephemeral. The plate system, rather than mantle viscosity, will modulate mantle cooling. The supercontinent cycle, with episodes of reorganization and massive magmatism, may be a manifestation of this far-from-equilibrium, driven from above, system. Geodynamics may be simpler than we think. Plate tectonics is certainly a more powerful concept once the concepts of rididity, elasticity, homogeneity, steady-state, equilibrium and uniformity are dropped or modified, as qualifiers of the system,as recommended in Occam's philosophy.
Helicon wave coupling in KSTAR plasmas for off-axis current drive in high electron pressure plasmas
NASA Astrophysics Data System (ADS)
Wang, S. J.; Wi, H. H.; Kim, H. J.; Kim, J.; Jeong, J. H.; Kwak, J. G.
2017-04-01
A helicon wave current drive is proposed as an efficient off-axis current drive in the high electron β plasmas that are expected in fusion reactors. A high frequency helicon wave coupling was analyzed using the surface impedance at a plasma boundary. A slow wave coupling, which may compete with the helicon wave coupling at a frequency of 500 MHz, is estimated to be lower than the fast wave coupling by an order of magnitude in the KSTAR edge plasma density and in practical Faraday shield misalignment with the magnetic pitch. A traveling wave antenna, which is a two port combline antenna, was analyzed using a simplified lumped element model. The results show that the traveling wave antenna provides load resiliency because of its insensitivity to loading resistance, provided that the loading resistance at a radiating element is limited within a practical range. The combline antenna is attractive because it does not require a matching system and exhibits a high selectivity of parallel refractive index. Based on the analysis, a seven element combline antenna was fabricated and installed at an off-mid-plane offset of 30 cm from the mid-plane in KSTAR. The low power RF characteristics measured during several plasma discharges showed no evidence of slow wave coupling. This is consistent with the expectation made through the surface impedance analysis which predicted low slow wave coupling. The wave coupling to the plasma is easily controlled by a radial outer-gap control and gas puffing. No plasma confinement degradation was observed during the radial outer-gap control of up to 3 cm in H-mode discharges. In a ELMy plasmas, only a small reflection peak was observed during a very short portion of the ELM bursting period. If the number of radiating elements is increased for high power operation, then complete load resiliency can be expected. A very large coupling can be problematic for maintaining a parallel refractive index, although this issue can be mitigated by increasing the number of elements.
Practical Considerations for Using Constant Force Springs in Space-Based Mechanisms
NASA Technical Reports Server (NTRS)
Williams, R. Brett; Fisher, Charles D.; Gallon, John C.
2013-01-01
Mechanical springs are a common element in mechanism from all walks of life; cars, watches, appliances, and many others. These springs generally exhibit a linear relationship between force and deflection. In small mechanisms, deflections are small so the variation in spring force between one position and another are generally small and do not influence the design or functionality of the device. However, as the spacecraft industry drives towards larger, deployable satellites, the distances a spring or springs must function over can become considerable so much so that the structural integrity of the device may be impacted. As such, an increasingly common mechanism element is the constant force spring- one that provides a constant force regardless of deflection. These elements are commonly in the conceptual design phase to deal with system-level large deflections, but in the detailed design or integration test phase they can pose significant implementation issues. This article addresses some of the detailed issues in order for these constant force springs to be properly designed into space systems.
Piezoelectric power generation using friction-induced vibration
NASA Astrophysics Data System (ADS)
Tadokoro, Chiharu; Matsumoto, Aya; Nagamine, Takuo; Sasaki, Shinya
2017-06-01
In order to examine the feasibility of power generation by using friction-induced vibration with a piezoelectric element, we performed experiments and numerical analysis. In the experiments, the generated power in the piezoelectric element and the displacement of an oscillator were measured by a newly developed apparatus that embodied a single-degree-of-freedom (1-DOF) system with friction. In the numerical analysis, an analytical model of a 1-DOF system with friction and piezoelectric element was proposed to simulate the experiments. The experimental results demonstrated that the power of a few microwatts was generated by sliding between a steel ball and a steel plate lubricated with glycerol. In this study, a maximum power of approximately 10 μW was generated at a driving velocity of 40 mm s-1 and a normal load of 15 N. The numerical results demonstrated good qualitative agreement with the experimental results. This implies that this analytical model can be applied to optimize the oscillator design in piezoelectric power generation using friction-induced vibration.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wallace, G. M.; Fitzgerald, E.; Johnson, D. K.
2014-02-12
Active stub tuning with a fast ferrite tuner (FFT) allows for the system to respond dynamically to changes in the plasma impedance such as during the L-H transition or edge localized modes (ELMs), and has greatly increased the effectiveness of fusion ion cyclotron range of frequency systems. A high power waveguide double-stub tuner is under development for use with the Alcator C-Mod lower hybrid current drive (LHCD) system. Exact impedance matching with a double-stub is possible for a single radiating element under most load conditions, with the reflection coefficient reduced from Γ to Γ{sup 2} in the “forbidden region.” Themore » relative phase shift between adjacent columns of a LHCD antenna is critical for control of the launched n{sub ∥} spectrum. Adding a double-stub tuning network will perturb the phase of the forward wave particularly if the unmatched reflection coefficient is high. This effect can be compensated by adjusting the phase of the low power microwave drive for each klystron amplifier. Cross-coupling of the reflected power between columns of the launcher must also be considered. The problem is simulated by cascading a scattering matrix for the plasma provided by a linear coupling model with the measured launcher scattering matrix and that of the FFTs. The solution is advanced in an iterative manner similar to the time-dependent behavior of the real system. System performance is presented under a range of edge density conditions from under-dense to over-dense and a range of launched n{sub ∥}.« less
Ice Detection and Mitigation Device
NASA Technical Reports Server (NTRS)
Gambino, Richard J. (Inventor); Gouldstone, Christopher (Inventor); Gutleber, Jonathan (Inventor); Hubble, David (Inventor); Trelewicz, Jason (Inventor)
2016-01-01
A method for deicing an aerostructure includes driving a sensing current through a heater element coated to an aerostructure, the heater element having a resistance that is temperature dependent. A resistance of the heater element is monitored. It is determined whether there is icing at the heater element using the monitored resistance of the heater element. A melting current is driven through the heater element when it is determined that there is icing at the heater element.
Analysis of the position of robotic cell components and its impact on energy consumption by robot
NASA Astrophysics Data System (ADS)
Banas, W.; Gwiazda, A.; Monica, Z.; Sekala, A.; Foit, K.
2016-08-01
Location elements in the robot cell is very important must provide reasonable access to technological points. This is a basic condition, but it is possible to shift these elements worth considering over other criteria. One of them can be energy consumption. This is an economic parameter and in most cases its improvement make shorten the working time an industrial robot. In most conventional mechanical systems you do not need to consume power in standby mode only for a move. Robot because of its construction, even if it does not move has enabled engines and is ready to move. In this case, the servo speed is zero. During this stop servo squeak. Low-speed motors cause the engine torque is reduced and increases power consumption. In larger robots are installed brakes that when the robot does not move mechanically hold the position. Off the robot has enabled brakes and remembers the position servo drives. Brakes must be released when the robot wants to move and drives hold the position.
A three degree of freedom manipulator used for store separation wind tunnel test
NASA Astrophysics Data System (ADS)
Wei, R.; Che, B.-H.; Sun, C.-B.; Zhang, J.; Lu, Y.-Q.
2018-06-01
A three degree of freedom manipulator is presented, which is used for store separation wind tunnel test. It is a kind of mechatronics product, have small volume and large moment of torque. The paper researched the design principle of wind tunnel test equipment, also introduced the transmission principle design, physical design, control system design, drive element selection calculation and verification, dynamics computation and static structural computation of the manipulator. To satisfy the design principle of wind tunnel test equipment, some optimization design are made include optimizes the structure of drive element and cable, fairing configuration, overall dimension so that to make the device more suitable for the wind tunnel test. Some tests are made to verify the parameters of the manipulator. The results show that the device improves the load from 100 Nm to 250 Nm, control accuracy from 0.1°to 0.05°in pitch and yaw, also improves load from 10 Nm to 20 Nm, control accuracy from 0.1°to 0.05°in roll.
Drive Train Normal Modes Analysis for the ERDA/NASA 100-Kilowatt Wind Turbine Generator
NASA Technical Reports Server (NTRS)
Sullivan, T. L.; Miller, D. R.; Spera, D. A.
1977-01-01
Natural frequencies, as a function of power were determined using a finite element model. Operating conditions investigated were operation with a resistive electrical load and operation synchronized to an electrical utility grid. The influence of certain drive train components on frequencies and mode shapes is shown. An approximate method for obtaining drive train natural frequencies is presented.
NASA Astrophysics Data System (ADS)
Thoma, Jean Ulrich
The fundamental principles and applications of the bond graph method, in which a system is represented on paper by letter elements and their interconnections (bonds), are presented in an introduction for engineering students. Chapters are devoted to simulation and graphical system models; bond graphs as networks for power and signal exchange; the simulation and design of mechanical engineering systems; the simulation of fluid power systems and hydrostatic devices; electrical circuits, drives, and components; practical procedures and problems of bond-graph-based numerical simulation; and applications to thermodynamics, chemistry, and biology. Also included are worked examples of applications to robotics, shocks and collisions, ac circuits, hydraulics, and a hydropneumatic fatigue-testing machine.
NASA Technical Reports Server (NTRS)
Hrabak, R. R.; Levy, D. W.; Finn, P.; Roskam, J.
1981-01-01
The use of pressure differentials in a flight control system was evaluated. The pressure profile around the test surface was determined using two techniques: (1) windtunnel data (actual); and (2) NASA/Langley Single Element Airfoil Computer Program (theoretical). The system designed to evaluate the concept of using pressure differentials is composed of a sensor drive and power amplifiers, actuator, position potentiometer, and a control surface. The characteristics (both desired and actual) of the system and each individual component were analyzed. The desired characteristics of the system as a whole are given. The flight control system developed, the testing procedures and data reduction methods used, and theoretical frequency response analysis are described.
Gillham, Michael; Pepper, Matthew; Kelly, Steve; Howells, Gareth
2017-01-01
Background : Many powered wheelchair users find their medical condition and their ability to drive the wheelchair will change over time. In order to maintain their independent mobility, the powered chair will require adjustment over time to suit the user's needs, thus regular input from healthcare professionals is required. These limited resources can result in the user having to wait weeks for appointments, resulting in the user losing independent mobility, consequently affecting their quality of life and that of their family and carers. In order to provide an adaptive assistive driving system, a range of features need to be identified which are suitable for initial system setup and can automatically provide data for re-calibration over the long term. Methods : A questionnaire was designed to collect information from powered wheelchair users with regard to their symptoms and how they changed over time. Another group of volunteer participants were asked to drive a test platform and complete a course which represented manoeuvring in a very confined space as quickly as possible. Two of those participants were also monitored over a longer period in their normal home daily environment. Features, thought to be suitable, were examined using pattern recognition classifiers to determine their suitability for identifying the changing user input over time. Results : The results are not designed to provide absolute insight into the individual user behaviour, as no ground truth of their ability has been determined, they do nevertheless demonstrate the utility of the measured features to provide evidence of the users' changing ability over time whilst driving a powered wheelchair. Conclusions : Determining the driving features and adjustable elements provides the initial step towards developing an adaptable assistive technology for the user when the ground truths of the individual and their machine have been learned by a smart pattern recognition system.
Gillham, Michael; Pepper, Matthew; Kelly, Steve; Howells, Gareth
2018-01-01
Background: Many powered wheelchair users find their medical condition and their ability to drive the wheelchair will change over time. In order to maintain their independent mobility, the powered chair will require adjustment over time to suit the user's needs, thus regular input from healthcare professionals is required. These limited resources can result in the user having to wait weeks for appointments, resulting in the user losing independent mobility, consequently affecting their quality of life and that of their family and carers. In order to provide an adaptive assistive driving system, a range of features need to be identified which are suitable for initial system setup and can automatically provide data for re-calibration over the long term. Methods: A questionnaire was designed to collect information from powered wheelchair users with regard to their symptoms and how they changed over time. Another group of volunteer participants were asked to drive a test platform and complete a course which represented manoeuvring in a very confined space as quickly as possible. Two of those participants were also monitored over a longer period in their normal home daily environment. Features, thought to be suitable, were examined using pattern recognition classifiers to determine their suitability for identifying the changing user input over time. Results: The results are not designed to provide absolute insight into the individual user behaviour, as no ground truth of their ability has been determined, they do nevertheless demonstrate the utility of the measured features to provide evidence of the users’ changing ability over time whilst driving a powered wheelchair. Conclusions: Determining the driving features and adjustable elements provides the initial step towards developing an adaptable assistive technology for the user when the ground truths of the individual and their machine have been learned by a smart pattern recognition system. PMID:29552641
Electrohydraulic linear actuator with two stepping motors controlled by overshoot-free algorithm
NASA Astrophysics Data System (ADS)
Milecki, Andrzej; Ortmann, Jarosław
2017-11-01
The paper describes electrohydraulic spool valves with stepping motors used as electromechanical transducers. A new concept of a proportional valve in which two stepping motors are working differentially is introduced. Such valve changes the fluid flow proportionally to the sum or difference of the motors' steps numbers. The valve design and principle of its operation is described. Theoretical equations and simulation models are proposed for all elements of the drive, i.e., the stepping motor units, hydraulic valve and cylinder. The main features of the valve and drive operation are described; some specific problem areas covering the nature of stepping motors and their differential work in the valve are also considered. The whole servo drive non-linear model is proposed and used further for simulation investigations. The initial simulation investigations of the drive with a new valve have shown that there is a significant overshoot in the drive step response, which is not allowed in positioning process. Therefore additional effort is spent to reduce the overshoot and in consequence reduce the settling time. A special predictive algorithm is proposed to this end. Then the proposed control method is tested and further improved in simulations. Further on, the model is implemented in reality and the whole servo drive system is tested. The investigation results presented in this paper, are showing an overshoot-free positioning process which enables high positioning accuracy.
DOT National Transportation Integrated Search
1981-02-01
A series of general risk-management countermeasures for speed Unsafe Driving Actions (UDAs) are described. First, countermeasure elements in three functional areas, detection, information, and action, are identified. Three comprehensive countermeasur...
Driving under the influence of alcohol : determining an optimum sanction.
DOT National Transportation Integrated Search
1971-01-01
Numerous elements must be considered in the design of an optimal statutory scheme for the definition and enforcement of the prohibition against driving under the influence of alcohol. Psychological factors determine the extent to which the statute ha...
An investigation of underwater sound propagation from pile driving.
DOT National Transportation Integrated Search
2011-12-01
The underwater noise from impact pile driving was studied by using a finite element model for the sound generation and a parabolic equation model for propagation. Results were compared with measurements taken with a vertical line array deployed durin...
Gutfrind, Christophe; Dufour, Laurent; Liebart, Vincent; Vannier, Jean-Claude; Vidal, Pierre
2016-01-01
The purpose of this article is to describe the design of a limited stroke actuator and the corresponding prototype to drive a Low Pressure (LP) Exhaust Gas Recirculation (EGR) valve for use in Internal Combustion Engines (ICEs). The direct drive actuator topology is an axial flux machine with two air gaps in order to minimize the rotor inertia and a bipolar surface-mounted permanent magnet in order to respect an 80° angular stroke. Firstly, the actuator will be described and optimized under constraints of a 150 ms time response, a 0.363 N·m minimal torque on an angular range from 0° to 80° and prototyping constraints. Secondly, the finite element method (FEM) using the FLUX-3D® software (CEDRAT, Meylan, France) will be used to check the actuator performances with consideration of the nonlinear effect of the iron material. Thirdly, a prototype will be made and characterized to compare its measurement results with the analytical model and the FEM model results. With these electromechanical behavior measurements, a numerical model is created with Simulink® in order to simulate an EGR system with this direct drive actuator under all operating conditions. Last but not least, the energy consumption of this machine will be estimated to evaluate the efficiency of the proposed EGR electromechanical system. PMID:27213398
Gutfrind, Christophe; Dufour, Laurent; Liebart, Vincent; Vannier, Jean-Claude; Vidal, Pierre
2016-05-20
The purpose of this article is to describe the design of a limited stroke actuator and the corresponding prototype to drive a Low Pressure (LP) Exhaust Gas Recirculation (EGR) valve for use in Internal Combustion Engines (ICEs). The direct drive actuator topology is an axial flux machine with two air gaps in order to minimize the rotor inertia and a bipolar surface-mounted permanent magnet in order to respect an 80° angular stroke. Firstly, the actuator will be described and optimized under constraints of a 150 ms time response, a 0.363 N·m minimal torque on an angular range from 0° to 80° and prototyping constraints. Secondly, the finite element method (FEM) using the FLUX-3D(®) software (CEDRAT, Meylan, France) will be used to check the actuator performances with consideration of the nonlinear effect of the iron material. Thirdly, a prototype will be made and characterized to compare its measurement results with the analytical model and the FEM model results. With these electromechanical behavior measurements, a numerical model is created with Simulink(®) in order to simulate an EGR system with this direct drive actuator under all operating conditions. Last but not least, the energy consumption of this machine will be estimated to evaluate the efficiency of the proposed EGR electromechanical system.
Comparing Acquisition Strategies: Open Architecture versus Product Lines
2010-04-30
software • New SOW language for accepting software deliveries – Enables third-party reuse • Additional SOW language regarding conducting software code walkthroughs and for using integrated development environments ...change the business environment must be the primary factor that drives the technical approach. Accordingly, there are business case decisions to be...elements of a system design should be made available to the customer to observe throughout the design process. Electronic access to the design environment
Entropy-driven loss of gas-phase Group 5 species from GOLD/3-5 compound semiconductor systems
NASA Astrophysics Data System (ADS)
Pugh, J. H.; Williams, R. S.
1986-02-01
Temperature dependent chemical interactions between Au and nine 3-5 compound semiconductors (3=A1, Ga, In and V=P, As, Sb) have been calculated using bulk thermodynamic properties. Enthalpic considerations alone are insufficient to predict metal/compound-semiconductor reactivities. The entropy of vaporization of the group 5 elements is shown to be an extremely important driving force for chemical reactions involving the 3-5's, since it enables several endothermic reactions to occur spontaneously under certain temperature and pressure conditions. Plots of either Gibb's free energies of reaction or equilibrium vapor pressure of the group 5 element versus temperature are used to predict critical reaction temperatures for each of the systems studied. These plots agree extremely well with previous experimental observations of thin film reactions of Au on GaAs.
Nuclear Cryogenic Propulsion Stage Conceptual Design and Mission Analysis
NASA Technical Reports Server (NTRS)
Kos, Larry D.; Russell, Tiffany E.
2014-01-01
The Nuclear Cryogenic Propulsion Stage (NCPS) is an in-space transportation vehicle, comprised of three main elements, designed to support a long-stay human Mars mission architecture beginning in 2035. The stage conceptual design and the mission analysis discussed here support the current nuclear thermal propulsion going on within partnership activity of NASA and the Department of Energy (DOE). The transportation system consists of three elements: 1) the Core Stage, 2) the In-line Tank, and 3) the Drop Tank. The driving mission case is the piloted flight to Mars in 2037 and will be the main point design shown and discussed. The corresponding Space Launch System (SLS) launch vehicle (LV) is also presented due to it being a very critical aspect of the NCPS Human Mars Mission architecture due to the strong relationship between LV lift capability and LV volume capacity.
Wang, Sihong; Lin, Long; Wang, Zhong Lin
2012-12-12
Harvesting energy from our living environment is an effective approach for sustainable, maintenance-free, and green power source for wireless, portable, or implanted electronics. Mechanical energy scavenging based on triboelectric effect has been proven to be simple, cost-effective, and robust. However, its output is still insufficient for sustainably driving electronic devices/systems. Here, we demonstrated a rationally designed arch-shaped triboelectric nanogenerator (TENG) by utilizing the contact electrification between a polymer thin film and a metal thin foil. The working mechanism of the TENG was studied by finite element simulation. The output voltage, current density, and energy volume density reached 230 V, 15.5 μA/cm(2), and 128 mW/cm(3), respectively, and an energy conversion efficiency as high as 10-39% has been demonstrated. The TENG was systematically studied and demonstrated as a sustainable power source that can not only drive instantaneous operation of light-emitting diodes (LEDs) but also charge a lithium ion battery as a regulated power module for powering a wireless sensor system and a commercial cell phone, which is the first demonstration of the nanogenerator for driving personal mobile electronics, opening the chapter of impacting general people's life by nanogenerators.
A motionless actuation system for magnetic shape memory devices
NASA Astrophysics Data System (ADS)
Armstrong, Andrew; Finn, Kevin; Hobza, Anthony; Lindquist, Paul; Rafla, Nader; Müllner, Peter
2017-10-01
Ni-Mn-Ga is a Magnetic Shape Memory (MSM) alloy that changes shape in response to a variable magnetic field. We can intentionally manipulate the shape of the material to function as an actuator, and the material can thus replace complicated small electromechanical systems. In previous work, a very simple and precise solid-state micropump was developed, but a mechanical rotation was required to translate the position of the magnetic field. This mechanical rotation defeats the purpose of the motionless solid-state device. Here we present a solid-state electromagnetic driver to linearly progress the position of the applied magnetic field and the associated shrinkage. The generated magnetic field was focused at either of two pole pieces, providing a mechanism for moving the localized shrinkage in the MSM element. We confirmed that our driver has sufficient strength to actuate the MSM element using optical microscopy. We validated the whole design by comparing results obtained with finite element analysis with the experimentally measured flux density. This drive system serves as a possible replacement to the mechanical rotation of the magnetic field by using a multi-pole electromagnet that sweeps the magnetic field across the MSM micropump element, solid-state switching the current to each pole piece in the multi-pole electromagnet.
Effect of DGPS failures on dynamic positioning of mobile drilling units in the North Sea.
Chen, Haibo; Moan, Torgeir; Verhoeven, Harry
2009-11-01
Basic features of differential global positioning system (DGPS), and its operational configuration on dynamically positioned (DP) mobile offshore drilling units in the North Sea are described. Generic failure modes of DGPS are discussed, and a critical DGPS failure which has the potential to cause drive-off for mobile drilling units is identified. It is the simultaneous erroneous position data from two DGPS's. Barrier method is used to analyze this critical DGPS failure. Barrier elements to prevent this failure are identified. Deficiencies of each barrier element are revealed based on the incidents and operational experiences in the North Sea. Recommendations to strengthen these barrier elements, i.e. to prevent erroneous position data from DGPS, are proposed. These recommendations contribute to the safety of DP operations of mobile offshore drilling units.
Touch-screen task-element times for improving SAE recommended practice J2365 : a first proposal.
DOT National Transportation Integrated Search
2015-10-01
This report describes the identification of task elements and the estimation of their times for in-vehicle tasks such as dialing a phone number or finding a song using a touch screen. These : elements were derived from an experiment in which 24 drive...
Resonance of magnetization excited by voltage in magnetoelectric heterostructures
NASA Astrophysics Data System (ADS)
Yu, Guoliang; Zhang, Huaiwu; Li, Yuanxun; Li, Jie; Zhang, Dainan; Sun, Nian
2018-04-01
Manipulation of magnetization dynamics is critical for spin-based devices. Voltage driven magnetization resonance is promising for realizing low-power information processing systems. Here, we show through Finite Element Method (FEM) simulations that magnetization resonance in nanoscale magnetic elements can be generated by a radio frequency (rf) voltage via the converse magnetoelectric (ME) effect. The magnetization dynamics induced by voltage in a ME heterostructures is simulated by taking into account the magnetoelastic and piezoelectric coupling mechanisms among magnetization, strain and voltage. The frequency of the excited magnetization resonance is equal to the driving rf voltage frequency. The proposed voltage driven magnetization resonance excitation mechanism opens a way toward energy-efficient spin based device applications.
System Identification for Nonlinear Control Using Neural Networks
NASA Technical Reports Server (NTRS)
Stengel, Robert F.; Linse, Dennis J.
1990-01-01
An approach to incorporating artificial neural networks in nonlinear, adaptive control systems is described. The controller contains three principal elements: a nonlinear inverse dynamic control law whose coefficients depend on a comprehensive model of the plant, a neural network that models system dynamics, and a state estimator whose outputs drive the control law and train the neural network. Attention is focused on the system identification task, which combines an extended Kalman filter with generalized spline function approximation. Continual learning is possible during normal operation, without taking the system off line for specialized training. Nonlinear inverse dynamic control requires smooth derivatives as well as function estimates, imposing stringent goals on the approximating technique.
A CRISPR Cas9-based gene drive platform for genetic interaction analysis in Candida albicans
Shapiro, Rebecca S.; Chavez, Alejandro; Porter, Caroline B. M.; Hamblin, Meagan; Kaas, Christian S.; DiCarlo, James E.; Zeng, Guisheng; Xu, Xiaoli; Revtovich, Alexey V.; Kirienko, Natalia V.; Wang, Yue; Church, George M.; Collins, James J.
2018-01-01
Candida albicans is the leading cause of fungal infections; yet, complex genetic interaction analysis remains cumbersome in this diploid pathogen. Here, we developed a CRISPR-Cas9-based ‘gene drive array’ (GDA) platform to facilitate efficient genetic analysis in C. albicans. In our system, a modified DNA donor molecule acts as a selfish genetic element, replaces the targeted site, and propagates to replace additional wild-type loci. Using mating-competent C. albicans haploids, each carrying a different gene drive disabling a gene of interest, we are able to create diploid strains that are homozygous double-deletion mutants. We generate double-gene deletion libraries to demonstrate this technology, targeting antifungal efflux and biofilm adhesion factors. We screen these libraries to identify virulence regulators and determine how genetic networks shift under diverse conditions. This platform transforms our ability to perform genetic interaction analysis in C. albicans and is readily extended to other fungal pathogens. PMID:29062088
Structural Health Monitoring for a Z-Type Special Vehicle
Yuan, Chaolin; Ren, Liang; Li, Hongnan
2017-01-01
Nowadays there exist various kinds of special vehicles designed for some purposes, which are different from regular vehicles in overall dimension and design. In that case, accidents such as overturning will lead to large economical loss and casualties. There are still no technical specifications to follow to ensure the safe operation and driving of these special vehicles. Owing to the poor efficiency of regular maintenance, it is more feasible and effective to apply real-time monitoring during the operation and driving process. In this paper, the fiber Bragg grating (FBG) sensors are used to monitor the safety of a z-type special vehicle. Based on the structural features and force distribution, a reasonable structural health monitoring (SHM) scheme is presented. Comparing the monitoring results with the finite element simulation results guarantees the accuracy and reliability of the monitoring results. Large amounts of data are collected during the operation and driving progress to evaluate the structural safety condition and provide reference for SHM systems developed for other special vehicles. PMID:28587161
Recurrent selection on the Winters sex-ratio genes in Drosophila simulans.
Kingan, Sarah B; Garrigan, Daniel; Hartl, Daniel L
2010-01-01
Selfish genes, such as meiotic drive elements, propagate themselves through a population without increasing the fitness of host organisms. X-linked (or Y-linked) meiotic drive elements reduce the transmission of the Y (X) chromosome and skew progeny and population sex ratios, leading to intense conflict among genomic compartments. Drosophila simulans is unusual in having a least three distinct systems of X chromosome meiotic drive. Here, we characterize naturally occurring genetic variation at the Winters sex-ratio driver (Distorter on the X or Dox), its progenitor gene (Mother of Dox or MDox), and its suppressor gene (Not Much Yang or Nmy), which have been previously mapped and characterized. We survey three North American populations as well as 13 globally distributed strains and present molecular polymorphism data at the three loci. We find that all three genes show signatures of selection in North America, judging from levels of polymorphism and skews in the site-frequency spectrum. These signatures likely result from the biased transmission of the driver and selection on the suppressor for the maintenance of equal sex ratios. Coalescent modeling indicates that the timing of selection is more recent than the age of the alleles, suggesting that the driver and suppressor are coevolving under an evolutionary "arms race." None of the Winters sex-ratio genes are fixed in D. simulans, and at all loci we find ancestral alleles, which lack the gene insertions and exhibit high levels of nucleotide polymorphism compared to the derived alleles. In addition, we find several "null" alleles that have mutations on the derived Dox background, which result in loss of drive function. We discuss the possible causes of the maintenance of presence-absence polymorphism in the Winters sex-ratio genes.
NASA Technical Reports Server (NTRS)
Wilcox, Brian (Inventor)
2004-01-01
A gas pipe explorer formed of a plurality of connecting elements, and an articulation element between the connected elements. The connected elements include drive capabilities, and the articulation element allows the connected elements to traverse gas pipes of arbitrary shapes and sizes. A sensor may sends the characteristics of the gas pipe, and the communication element may send back those sends characteristics. The communication can be wired, over a tether connecting the device to a remote end. Alternatively, the connection can be wireless, driven by either a generator or a battery.
Integrative and conjugative elements and their hosts: composition, distribution and organization.
Cury, Jean; Touchon, Marie; Rocha, Eduardo P C
2017-09-06
Conjugation of single-stranded DNA drives horizontal gene transfer between bacteria and was widely studied in conjugative plasmids. The organization and function of integrative and conjugative elements (ICE), even if they are more abundant, was only studied in a few model systems. Comparative genomics of ICE has been precluded by the difficulty in finding and delimiting these elements. Here, we present the results of a method that circumvents these problems by requiring only the identification of the conjugation genes and the species' pan-genome. We delimited 200 ICEs and this allowed the first large-scale characterization of these elements. We quantified the presence in ICEs of a wide set of functions associated with the biology of mobile genetic elements, including some that are typically associated with plasmids, such as partition and replication. Protein sequence similarity networks and phylogenetic analyses revealed that ICEs are structured in functional modules. Integrases and conjugation systems have different evolutionary histories, even if the gene repertoires of ICEs can be grouped in function of conjugation types. Our characterization of the composition and organization of ICEs paves the way for future functional and evolutionary analyses of their cargo genes, composed of a majority of unknown function genes. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.
Sex drives intracellular conflict in yeast.
Harrison, E; MacLean, R C; Koufopanou, V; Burt, A
2014-08-01
Theory predicts that sex can drive the evolution of conflict within the cell. During asexual reproduction, genetic material within the cell is inherited as a single unit, selecting for cooperation both within the genome as well as between the extra-genomic elements within the cell (e.g. plasmids and endosymbionts). Under sexual reproduction, this unity is broken down as parental genomes are distributed between meiotic progeny. Genetic elements able to transmit to more than 50% of meiotic progeny have a transmission advantage over the rest of the genome and are able to spread, even where they reduce the fitness of the individual as a whole. Sexual reproduction is therefore expected to drive the evolution of selfish genetic elements (SGEs). Here, we directly test this hypothesis by studying the evolution of two independent SGEs, the 2-μm plasmid and selfish mitochondria, in populations of Saccharomyces cerevisiae. Following 22 rounds of sexual reproduction, 2-μm copy number increased by approximately 13.2 (±5.6) copies per cell, whereas in asexual populations copy number decreased by approximately 5.1 (±1.5) copies per cell. Given that the burden imposed by this parasite increases with copy number, these results support the idea that sex drives the evolution of increased SGE virulence. Moreover, we found that mitochondria that are respiratory-deficient rapidly invaded sexual but not asexual populations, demonstrating that frequent outcrossed sex can drive the de novo evolution of genetic parasites. Our study highlights the genomic perils of sex and suggests that SGEs may play a key role in driving major evolutionary transitions, such as uniparental inheritance. © 2014 The Authors. Journal of Evolutionary Biology © 2014 European Society For Evolutionary Biology.
Real-Time Simulation of Ares I Launch Vehicle
NASA Technical Reports Server (NTRS)
Tobbe, Patrick; Matras, Alex; Wilson, Heath; Alday, Nathan; Walker, David; Betts, Kevin; Hughes, Ryan; Turbe, Michael
2009-01-01
The Ares Real-Time Environment for Modeling, Integration, and Simulation (ARTEMIS) has been developed for use by the Ares I launch vehicle System Integration Laboratory (SIL) at the Marshall Space Flight Center (MSFC). The primary purpose of the Ares SIL is to test the vehicle avionics hardware and software in a hardware-in-the-loop (HWIL) environment to certify that the integrated system is prepared for flight. ARTEMIS has been designed to be the real-time software backbone to stimulate all required Ares components through high-fidelity simulation. ARTEMIS has been designed to take full advantage of the advances in underlying computational power now available to support HWIL testing. A modular real-time design relying on a fully distributed computing architecture has been achieved. Two fundamental requirements drove ARTEMIS to pursue the use of high-fidelity simulation models in a real-time environment. First, ARTEMIS must be used to test a man-rated integrated avionics hardware and software system, thus requiring a wide variety of nominal and off-nominal simulation capabilities to certify system robustness. The second driving requirement - derived from a nationwide review of current state-of-the-art HWIL facilities - was that preserving digital model fidelity significantly reduced overall vehicle lifecycle cost by reducing testing time for certification runs and increasing flight tempo through an expanded operational envelope. These two driving requirements necessitated the use of high-fidelity models throughout the ARTEMIS simulation. The nature of the Ares mission profile imposed a variety of additional requirements on the ARTEMIS simulation. The Ares I vehicle is composed of multiple elements, including the First Stage Solid Rocket Booster (SRB), the Upper Stage powered by the J- 2X engine, the Orion Crew Exploration Vehicle (CEV) which houses the crew, the Launch Abort System (LAS), and various secondary elements that separate from the vehicle. At launch, the integrated vehicle stack is composed of these stages, and throughout the mission, various elements separate from the integrated stack and tumble back towards the earth. ARTEMIS must be capable of simulating the integrated stack through the flight as well as propagating each individual element after separation. In addition, abort sequences can lead to other unique configurations of the integrated stack as the timing and sequence of the stage separations are altered.
DOT National Transportation Integrated Search
2015-07-01
Driving is essential to maintaining independence. For most Americans preserving personal mobility is a : key element to retaining jobs, friends, activities and the basic necessities to maintain a household. This : is particularly true for older peopl...
A New Clinical HIFU System (Teleson II)
NASA Astrophysics Data System (ADS)
Ma, Yixin; Symonds-Tayler, Richard; Rivens, Ian H.; ter Haar, Gail R.
2007-05-01
Previous clinical trials with our first prototype HIFU system (Teleson I) for the treatment of liver tumors, demonstrated a major challenge to be treatment of those tumors located behind the ribs. We have designed a new multi-element transducer for rib sparing. Initial simulation and experimental results (using a single channel power amplifier) are very encouraging. A new clinical HIFU system which can drive the multi-element transducer and control each channel independently is being designed and constructed. This second version of a clinical prototype HIFU system consists of a 3D motorised gantry, a multi-channel signal generator, a multi-channel power amplifier, a user interface PC, an embedded controller and auxiliary circuits for real-time interleaving/synchronization control and a to-be-implemented safety monitoring and data logging unit. For multi-element transducers, each element can be individually switched on and off for rib sparing, and phase and amplitude modulated for potential phased array applications. The multi-channel power amplifier can be switched on/off very rapidly at required intervals to interleave with ultrasound B-Scan imaging for HIFU monitoring or radiation force elastography imaging via a dedicated interleaving/timing module. The gantry movement can also be synchronised with power amplifier on/off and phase/amplitude updating for lesion generation under a wide variety of conditions including single lesions, lesion arrays and lesions "tracks" created whilst translating the active transducer. Results from testing the system using excised tissue will be presented.
The group employed model as a foundation for health care delivery reform.
Minott, Jenny; Helms, David; Luft, Harold; Guterman, Stuart; Weil, Henry
2010-04-01
With a focus on delivering low-cost, high-quality care, several organizations using the group employed model (GEM)-with physician groups whose primary and specialty care physicians are salaried or under contract-have been recognized for creating a culture of patient-centeredness and accountability, even in a toxic fee-for-service environment. The elements that leaders of such organizations identify as key to their success are physician leadership that promotes trust in the organization, integration that promotes teamwork and coordination, governance and strategy that drive results, transparency and health information technology that drive continual quality improvement, and a culture of accountability that focuses providers on patient needs and responsibility for effective care and efficient use of resources. These organizations provide important lessons for health care delivery system reform.
Human Mars Ascent Vehicle Performance Sensitivities
NASA Technical Reports Server (NTRS)
Polsgrove, Tara P.; Thomas, Herbert D.
2016-01-01
Human Mars mission architecture studies have shown that the ascent vehicle mass drives performance requirements for the descent and in-space transportation elements. Understanding the sensitivity of Mars ascent vehicle (MAV) mass to various mission and vehicle design choices enables overall transportation system optimization. This paper presents the results of a variety of sensitivity trades affecting MAV performance including: landing site latitude, target orbit, initial thrust to weight ratio, staging options, specific impulse, propellant type and engine design.
Defense AT&L (Volume 35, Number 5, September-October 2006)
2006-10-01
percent of production. The criti- Defense AT&L: September-October 2006 8 cal path elements driving the IOT &E schedule are not pro- duction hardware...reduced costs, and successful completion of work in the scheduled time. 30 The Commodity Approach to Aircraft Protection Systems Capt. Bill Chubb, USN The...piece of Littoral Combat Ship Two during the ship’s keel laying ceremony. The Navy’s second Littoral Combat Ship is scheduled for commissioning in
NASA Technical Reports Server (NTRS)
Smith, John W.; Lock, Wilton P.; Payne, Gordon A.
1992-01-01
The advanced fighter technology integration, the AFTI/F-111 aircraft, is a preproduction F-111A testbed research airplane that was fitted with a smooth variable-camber mission adaptive wing. The camber was positioned and controlled by flexing the upper skins through rotary actuators and linkages driven by power drive units. The wing camber and control system are described. The measured servoactuator frequency responses are presented along with analytical predictions derived from the integrated characteristics of the control elements. A mission adaptive wing system chronology is used to illustrate and assess the reliability and dependability of the servoactuator system during 1524 hours of ground tests and 145 hours of flight testing.
Test and Verification Approach for the NASA Constellation Program
NASA Technical Reports Server (NTRS)
Strong, Edward
2008-01-01
This viewgraph presentation is a test and verification approach for the NASA Constellation Program. The contents include: 1) The Vision for Space Exploration: Foundations for Exploration; 2) Constellation Program Fleet of Vehicles; 3) Exploration Roadmap; 4) Constellation Vehicle Approximate Size Comparison; 5) Ares I Elements; 6) Orion Elements; 7) Ares V Elements; 8) Lunar Lander; 9) Map of Constellation content across NASA; 10) CxP T&V Implementation; 11) Challenges in CxP T&V Program; 12) T&V Strategic Emphasis and Key Tenets; 13) CxP T&V Mission & Vision; 14) Constellation Program Organization; 15) Test and Evaluation Organization; 16) CxP Requirements Flowdown; 17) CxP Model Based Systems Engineering Approach; 18) CxP Verification Planning Documents; 19) Environmental Testing; 20) Scope of CxP Verification; 21) CxP Verification - General Process Flow; 22) Avionics and Software Integrated Testing Approach; 23) A-3 Test Stand; 24) Space Power Facility; 25) MEIT and FEIT; 26) Flight Element Integrated Test (FEIT); 27) Multi-Element Integrated Testing (MEIT); 28) Flight Test Driving Principles; and 29) Constellation s Integrated Flight Test Strategy Low Earth Orbit Servicing Capability.
Spectral element simulation of precession driven flows in the outer cores of spheroidal planets
NASA Astrophysics Data System (ADS)
Vormann, Jan; Hansen, Ulrich
2015-04-01
A common feature of the planets in the solar system is the precession of the rotation axes, driven by the gravitational influence of another body (e.g. the Earth's moon). In a precessing body, the rotation axis itself is rotating around another axis, describing a cone during one precession period. Similar to the coriolis and centrifugal force appearing from the transformation to a rotating system, the addition of precession adds another term to the Navier-Stokes equation, the so called Poincaré force. The main geophysical motivation in studying precession driven flows comes from their ability to act as magnetohydrodynamic dynamos in planets and moons. Precession may either act as the only driving force or operate together with other forces such as thermochemical convection. One of the challenges in direct numerical simulations of such flows lies in the spheroidal shape of the fluid volume, which should not be neglected since it contributes an additional forcing trough pressure torques. Codes developed for the simulation of flows in spheres mostly use efficient global spectral algorithms that converge fast, but lack geometric flexibility, while local methods are usable in more complex shapes, but often lack high accuracy. We therefore adapted the spectral element code Nek5000, developed at Argonne National Laboratory, to the problem. The spectral element method is capable of solving for the flow in arbitrary geometries while still offering spectral convergence. We present first results for the simulation of a purely hydrodynamic, precession-driven flow in a spheroid with no-slip boundaries and an inner core. The driving by the Poincaré force is in a range where theoretical work predicts multiple solutions for a laminar flow. Our simulations indicate a transition to turbulent flows for Ekman numbers of 10-6 and lower.
Garcia, E.J.; Christenson, T.R.; Polosky, M.A.
1999-06-29
A millimeter-sized machine, including electromagnetic circuits adapted to convert electromagnetic energy to mechanical energy, for engaging and operating external mechanical loads. A plurality of millimeter-sized magnetic actuators operate out of phase with each other to control a plurality of millimeter-sized structural elements to drive an external mechanical load. Each actuator is connected to a link. Each link, in turn, is connected to a drive pinion at another similar pivoting joint. When the magnetic actuators are energized, each drive pinion is then capable of driving a larger output gear in gear-like fashion to produce positive torque about the drive pinion center at all angular positions of the output gear. 29 figs.
Garcia, Ernest J.; Christenson, Todd R.; Polosky, Marc A.
1999-01-01
A millimeter-sized machine, including electromagnetic circuits adapted to convert electromagnetic energy to mechanical energy, for engaging and operating external mechanical loads. A plurality of millimeter-sized magnetic actuators operate out of phase with each other to control a plurality of millimeter-sized structural elements to drive an external mechanical load. Each actuator is connected to a link. Each link, in turn, is connected to a drive pinion at another similar pivoting joint. When the magnetic actuators are energized, each drive pinion is then capable of driving a larger output gear in gear-like fashion to produce positive torque about the drive pinion center at all angular positions of the output gear.
Lidar Electro-Optic Beam Switch with a Liquid Crystal Variable Retarder
NASA Technical Reports Server (NTRS)
Baer, James
2012-01-01
A document discusses a liquid crystal variable retarder, an electro-optic element that changes the polarization of an optical beam in response to a low-voltage electronic signal. This device can be fabricated so that the element creates, among other states, a half-wave of retardance that can be reduced to a very small retardance. When aligned to a polarized source, this can act to rotate the polarization by 90 in one state, but generate no rotation in the other state. If the beam is then incident on a polarization beam splitter, it will efficiently switch from one path to the other when the voltage is applied. The laser beam switching system has no moving parts, improving reliability over mechanical switching. It is low cost, tolerant of high laser power density, and needs only simple drive electronics, minimizing the required system resources.
Optical signal processing of spatially distributed sensor data in smart structures
NASA Technical Reports Server (NTRS)
Bennett, K. D.; Claus, R. O.; Murphy, K. A.; Goette, A. M.
1989-01-01
Smart structures which contain dense two- or three-dimensional arrays of attached or embedded sensor elements inherently require signal multiplexing and processing capabilities to permit good spatial data resolution as well as the adequately short calculation times demanded by real time active feedback actuator drive circuitry. This paper reports the implementation of an in-line optical signal processor and its application in a structural sensing system which incorporates multiple discrete optical fiber sensor elements. The signal processor consists of an array of optical fiber couplers having tailored s-parameters and arranged to allow gray code amplitude scaling of sensor inputs. The use of this signal processor in systems designed to indicate the location of distributed strain and damage in composite materials, as well as to quantitatively characterize that damage, is described. Extension of similar signal processing methods to more complicated smart materials and structures applications are discussed.
NASA Astrophysics Data System (ADS)
Crane, D. T.
2011-05-01
High-power-density, segmented, thermoelectric (TE) elements have been intimately integrated into heat exchangers, eliminating many of the loss mechanisms of conventional TE assemblies, including the ceramic electrical isolation layer. Numerical models comprising simultaneously solved, nonlinear, energy balance equations have been created to simulate these novel architectures. Both steady-state and transient models have been created in a MATLAB/Simulink environment. The models predict data from experiments in various configurations and applications over a broad range of temperature, flow, and current conditions for power produced, efficiency, and a variety of other important outputs. Using the validated models, devices and systems are optimized using advanced multiparameter optimization techniques. Devices optimized for particular steady-state operating conditions can then be dynamically simulated in a transient operating model. The transient model can simulate a variety of operating conditions including automotive and truck drive cycles.
Elements and polycyclic aromatic hydrocarbons in exhaust particles emitted by light-duty vehicles.
Alves, Célia A; Barbosa, Cátia; Rocha, Sónia; Calvo, Ana; Nunes, Teresa; Cerqueira, Mário; Pio, Casimiro; Karanasiou, Angeliki; Querol, Xavier
2015-08-01
The main purpose of this work was to evaluate the chemical composition of particulate matter (PM) emitted by eight different light-duty vehicles. Exhaust samples from petrol and diesel cars (Euro 3 to Euro 5) were collected in a chassis dynamometer facility. To simulate the real-world driving conditions, three ARTEMIS cycles were followed: road, to simulate a fluid traffic flow and urban with hot and cold starts, to simulate driving conditions in cities. Samples were analysed for the water-soluble ions, for the elemental composition and for polycyclic aromatic hydrocarbons (PAHs), respectively, by ion chromatography, inductively coupled plasma atomic emission spectroscopy (ICP-AES), inductively coupled plasma mass spectrometry (ICP-MS) and gas chromatography-mass spectrometry (GC-MS). Nitrate and phosphate were the major water-soluble ions in the exhaust particles emitted from diesel and petrol vehicles, respectively. The amount of material emitted is affected by the vehicle age. For vehicles ≥Euro 4, most elements were below the detection limits. Sodium, with emission factors in the ranges 23.5-62.4 and 78.2-227μg km(-1), for petrol and diesel Euro 3 vehicles, respectively, was the major element. The emission factors of metallic elements indicated that diesel vehicles release three to five times more than petrol automobiles. Element emissions under urban cycles are higher than those found for on-road driving, being three or four times higher, for petrol vehicles, and two or three times, for diesel vehicles. The difference between cycles is mainly due to the high emissions for the urban cycle with hot start-up. As registered for elements, most of the PAH emissions for vehicles ≥Euro 4 were also below the detection limits. Regardless of the vehicle models or driving cycles, the two- to four-ring PAHs were always dominant. Naphthalene, with emission factors up to 925 μg km(-1), was always the most abundant PAH. The relative cancer risk associated with naphthalene was estimated to be up to several orders of magnitude higher than any of the chemical species found in the PM phase. The highest PAH emission factors were registered for diesel-powered vehicles. The condition of the vehicle can exert a decisive influence on both element and PAH emissions.
Sinusoidal input describing function for hysteresis followed by elementary backlash
NASA Technical Reports Server (NTRS)
Ringland, R. F.
1976-01-01
The author proposes a new sinusoidal input describing function which accounts for the serial combination of hysteresis followed by elementary backlash in a single nonlinear element. The output of the hysteresis element drives the elementary backlash element. Various analytical forms of the describing function are given, depending on the a/A ratio, where a is the half width of the hysteresis band or backlash gap, and A is the amplitude of the assumed input sinusoid, and on the value of the parameter representing the fraction of a attributed to the backlash characteristic. The negative inverse describing function is plotted on a gain-phase plot, and it is seen that a relatively small amount of backlash leads to domination of the backlash character in the describing function. The extent of the region of the gain-phase plane covered by the describing function is such as to guarantee some form of limit cycle behavior in most closed-loop systems.
Research on evaluation techniques for immersive multimedia
NASA Astrophysics Data System (ADS)
Hashim, Aslinda M.; Romli, Fakaruddin Fahmi; Zainal Osman, Zosipha
2013-03-01
Nowadays Immersive Multimedia covers most usage in tremendous ways, such as healthcare/surgery, military, architecture, art, entertainment, education, business, media, sport, rehabilitation/treatment and training areas. Moreover, the significant of Immersive Multimedia to directly meet the end-users, clients and customers needs for a diversity of feature and purpose is the assembly of multiple elements that drive effective Immersive Multimedia system design, so evaluation techniques is crucial for Immersive Multimedia environments. A brief general idea of virtual environment (VE) context and `realism' concept that formulate the Immersive Multimedia environments is then provided. This is followed by a concise summary of the elements of VE assessment technique that is applied in Immersive Multimedia system design, which outlines the classification space for Immersive Multimedia environments evaluation techniques and gives an overview of the types of results reported. A particular focus is placed on the implications of the Immersive Multimedia environments evaluation techniques in relation to the elements of VE assessment technique, which is the primary purpose of producing this research. The paper will then conclude with an extensive overview of the recommendations emanating from the research.
Demand Response Advanced Controls Framework and Assessment of Enabling Technology Costs
DOE Office of Scientific and Technical Information (OSTI.GOV)
Potter, Jennifer; Cappers, Peter
The Demand Response Advanced Controls Framework and Assessment of Enabling Technology Costs research describe a variety of DR opportunities and the various bulk power system services they can provide. The bulk power system services are mapped to a generalized taxonomy of DR “service types”, which allows us to discuss DR opportunities and bulk power system services in fewer yet broader categories that share similar technological requirements which mainly drive DR enablement costs. The research presents a framework for the costs to automate DR and provides descriptions of the various elements that drive enablement costs. The report introduces the various DRmore » enabling technologies and end-uses, identifies the various services that each can provide to the grid and provides the cost assessment for each enabling technology. In addition to a report, this research includes a Demand Response Advanced Controls Database and User Manual. They are intended to provide users with the data that underlies this research and instructions for how to use that database more effectively and efficiently.« less
Dynamics of neuronal circuits in addiction: reward, antireward, and emotional memory.
Koob, G F
2009-05-01
Drug addiction is conceptualized as chronic, relapsing compulsive use of drugs with significant dysregulation of brain hedonic systems. Compulsive drug use is accompanied by decreased function of brain substrates for drug positive reinforcement and recruitment of brain substrates mediating the negative reinforcement of motivational withdrawal. The neural substrates for motivational withdrawal ("dark side" of addiction) involve recruitment of elements of the extended amygdala and the brain stress systems, including corticotropin-releasing factor and norepinephrine. These changes, combined with decreased reward function, are hypothesized to persist in the form of an allostatic state that forms a powerful motivational background for relapse. Relapse also involves a key role for the basolateral amygdala in mediating the motivational effects of stimuli previously paired with drug seeking and drug motivational withdrawal. The basolateral amygdala has a key role in mediating emotional memories in general. The hypothesis argued here is that brain stress systems activated by the motivational consequences of drug withdrawal can not only form the basis for negative reinforcement that drives drug seeking, but also potentiate associative mechanisms that perpetuate the emotional state and help drive the allostatic state of addiction.
Driving with indirect viewing sensors: understanding the visual perception issues
NASA Astrophysics Data System (ADS)
O'Kane, Barbara L.
1996-05-01
Visual perception is one of the most important elements of driving in that it enables the driver to understand and react appropriately to the situation along the path of the vehicle. The visual perception of the driver is enabled to the greatest extent while driving during the day. Noticeable decrements in visual acuity, range of vision, depth of field and color perception occur at night and under certain weather conditions. Indirect viewing sensors, utilizing various technologies and spectral bands, may assist the driver's normal mode of driving. Critical applications in the military as well as other official activities may require driving at night without headlights. In these latter cases, it is critical that the device, being the only source of scene information, provide the required scene cues needed for driving on, and often-times, off road. One can speculate about the scene information that a driver needs, such as road edges, terrain orientation, people and object detection in or near the path of the vehicle, and so on. But the perceptual qualities of the scene that give rise to these perceptions are little known and thus not quantified for evaluation of indirect viewing devices. This paper discusses driving with headlights and compares the scene content with that provided by a thermal system in the 8 - 12 micrometers micron spectral band, which may be used for driving at some time. The benefits and advantages of each are discussed as well as their limitations in providing information useful for the driver who must make rapid and critical decisions based upon the scene content available. General recommendations are made for potential avenues of development to overcome some of these limitations.
Elastic Multi-scale Mechanisms: Computation and Biological Evolution.
Diaz Ochoa, Juan G
2018-01-01
Explanations based on low-level interacting elements are valuable and powerful since they contribute to identify the key mechanisms of biological functions. However, many dynamic systems based on low-level interacting elements with unambiguous, finite, and complete information of initial states generate future states that cannot be predicted, implying an increase of complexity and open-ended evolution. Such systems are like Turing machines, that overlap with dynamical systems that cannot halt. We argue that organisms find halting conditions by distorting these mechanisms, creating conditions for a constant creativity that drives evolution. We introduce a modulus of elasticity to measure the changes in these mechanisms in response to changes in the computed environment. We test this concept in a population of predators and predated cells with chemotactic mechanisms and demonstrate how the selection of a given mechanism depends on the entire population. We finally explore this concept in different frameworks and postulate that the identification of predictive mechanisms is only successful with small elasticity modulus.
Heinze, Dirk; Breddermann, Dominik; Zrenner, Artur; Schumacher, Stefan
2015-10-05
Sources of single photons are key elements for applications in quantum information science. Among the different sources available, semiconductor quantum dots excel with their integrability in semiconductor on-chip solutions and the potential that photon emission can be triggered on demand. Usually, the photon is emitted from a single-exciton ground state. Polarization of the photon and time of emission are either probabilistic or pre-determined by electronic properties of the system. Here, we study the direct two-photon emission from the biexciton. The two-photon emission is enabled by a laser pulse driving the system into a virtual state inside the band gap. From this intermediate state, the single photon of interest is then spontaneously emitted. We show that emission through this higher-order transition provides a versatile approach to generate a single photon. Through the driving laser pulse, polarization state, frequency and emission time of the photon can be controlled on-the-fly.
Development and Research of Peristaltic Multiphase Piezoelectric Micro-Pump
ERIC Educational Resources Information Center
Vinogradov, Alexander N.; Ivanikin, Igor A.; Lubchenco, Roman V.; Matveev, Yegor V.; Titov, Pavel A.
2016-01-01
The paper presents the results of a study of existing models and mathematical representations of a range of truly peristaltic multiphase micro-pumps with a piezoelectric actuator (piezo drive). Piezo drives with different types of substrates use vertical movements at deformation of individual piezoelectric elements, which define device…
DOT National Transportation Integrated Search
2006-04-01
New teenaged drivers have the highest accident rates of any group of drivers. Research is needed to determine how to safely equip novice drivers with the important elements of experience before they encounter a need for it in an actual driving situat...
DOT National Transportation Integrated Search
2006-10-01
New teenaged drivers have the highest accident rates of any group of drivers. Research is needed to : determine how to safely equip novice drivers with the important elements of experience before they encounter : a need for it in an actual driving si...
Dynamic simulation of road vehicle door window regulator mechanism of cross arm type
NASA Astrophysics Data System (ADS)
Miklos, I. Zs; Miklos, C.; Alic, C.
2017-01-01
The paper presents issues related to the dynamic simulation of a motor-drive operating mechanism of cross arm type, for the manipulation of road vehicle door windows, using Autodesk Inventor Professional software. The dynamic simulation of the mechanism involves a 3D modelling, kinematic coupling, drive motion parameters and external loads, as well as the graphically view of the kinematic and kinetostatic results for the various elements and kinematic couplings of the mechanism, under real operating conditions. Also, based on the results, the analysis of the mechanism components has been carried out using the finite element method.
78 FR 40053 - Airworthiness Directives; Eurocopter Deutschland GmbH Helicopters
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-03
... filter element for a chip. If the analysis indicates Stage III as defined by the ASB, this proposed AD would require removing and inspecting the oil filter element for a chip within 10 hours TIS. If there are no chips, we propose cleaning the oil filter element and chip detector, inspecting the drive stage...
Fast response of mechatronics module for robotic
NASA Astrophysics Data System (ADS)
Bukhanov, S. S.; Gryzlov, A. A.; Tsirkunenko, A. T.
2018-05-01
The synthesis technique, the mathematical model and results of experimental investigation of the control system of the robotic complex mechatronic module are presented in the article. It is shown that in most cases the dynamic system can be approximated by the serial connection of two first-order aperiodic links, while the speed in the torque control loop can reach 200-300 rad/s. The specified speed of the system was achieved due to improved specific weight and dimensions parameters of the electric drive (element of the mechatronic system) made on the basis of a contactless motor. The obtained results indicate the possibility of successful application of the proposed mechatronic module for objects of robotized systems in which the reference signal changes at a frequency not exceeding 50 Hz.
SW-MW infrared spectrometer for lunar mission
NASA Astrophysics Data System (ADS)
Banerjee, Arup; Biswas, Amiya; Joshi, Shaunak; Kumar, Ankush; Rehman, Sami; Sharma, Satish; Somani, Sandip; Bhati, Sunil; Karelia, Jitendra; Saxena, Anish; Chowdhury, Arup R.
2016-04-01
SW-MW Imaging Infrared Spectrometer, the Hyperspectral optical imaging instrument is envisaged to map geomorphology and mineralogy of lunar surface. The instrument is designed to image the electro-magnetic energy emanating from moon's surface with high spectral and spatial resolution for the mission duration from an altitude of 100 km. It is designed to cover 0.8 to 5 μm in 250 spectral bands with GSD 80m and swath 20km. Primarily, there are three basic optical segments in the spectrometer. They are fore optics, dispersing element and focusing elements. The payload is designed around a custom developed multi-blaze convex grating optimized for system throughput. The considerations for optimization are lunar radiation, instrument background, optical throughput, and detector sensitivity. HgCdTe (cooled using a rotary stirling cooler) based detector array (500x256 elements, 30μm) is being custom developed for the spectrometer. Stray light background flux is minimized using a multi-band filter cooled to cryogenic temperature. Mechanical system realization is being performed considering requirements such as structural, opto-mechanical, thermal, and alignment. The entire EOM is planned to be maintained at 240K to reduce and control instrument background. Al based mirror, grating, and EOM housing is being developed to maintain structural requirements along with opto- mechanical and thermal. Multi-tier radiative isolation and multi-stage radiative cooling approach is selected for maintaining the EOM temperature. EOM along with precision electronics packages are planned to be placed on the outer and inner side of Anti-sun side (ASS) deck. Power and Cooler drive electronics packages are planned to be placed on bottom side of ASS panel. Cooler drive electronics is being custom developed to maintain the detector temperature within 100mK during the imaging phase. Low noise detector electronics development is critical for maintaining the NETD requirements at different target temperatures. Subsequent segments of the paper bring out system design aspects and trade-off analyses.
Actuators of 3-element unimorph deformable mirror
NASA Astrophysics Data System (ADS)
Fu, Tianyang; Ning, Yu; Du, Shaojun
2016-10-01
Kinds of wavefront aberrations exist among optical systems because of atmosphere disturbance, device displacement and a variety of thermal effects, which disturb the information of transmitting beam and restrain its energy. Deformable mirror(DM) is designed to adjust these wavefront aberrations. Bimorph DM becomes more popular and more applicable among adaptive optical(AO) systems with advantages in simple structure, low cost and flexible design compared to traditional discrete driving DM. The defocus aberration accounted for a large proportion of all wavefront aberrations, with a simpler surface and larger amplitude than others, so it is very useful to correct the defocus aberration effectively for beam controlling and aberration adjusting of AO system. In this study, we desired on correcting the 3rd and 10th Zernike modes, analyze the characteristic of the 3rd and 10th defocus aberration surface distribution, design 3-element actuators unimorph DM model study on its structure and deformation principle theoretically, design finite element models of different electrode configuration with different ring diameters, analyze and compare effects of different electrode configuration and different fixing mode to DM deformation capacity through COMSOL finite element software, compare fitting efficiency of DM models to the 3rd and 10th Zernike modes. We choose the inhomogeneous electrode distribution model with better result, get the influence function of every electrode and the voltage-PV relationship of the model. This unimorph DM is suitable for the AO system with a mainly defocus aberration.
Macias, Vanessa M; Jimenez, Alyssa J; Burini-Kojin, Bianca; Pledger, David; Jasinskiene, Nijole; Phong, Celine Hien; Chu, Karen; Fazekas, Aniko; Martin, Kelcie; Marinotti, Osvaldo; James, Anthony A
2017-08-01
Transposons are a class of selfish DNA elements that can mobilize within a genome. If mobilization is accompanied by an increase in copy number (replicative transposition), the transposon may sweep through a population until it is fixed in all of its interbreeding members. This introgression has been proposed as the basis for drive systems to move genes with desirable phenotypes into target species. One such application would be to use them to move a gene conferring resistance to malaria parasites throughout a population of vector mosquitos. We assessed the feasibility of using the piggyBac transposon as a gene-drive mechanism to distribute anti-malarial transgenes in populations of the malaria vector, Anopheles stephensi. We designed synthetic gene constructs that express the piggyBac transposase in the female germline using the control DNA of the An. stephensi nanos orthologous gene linked to marker genes to monitor inheritance. Two remobilization events were observed with a frequency of one every 23 generations, a rate far below what would be useful to drive anti-pathogen transgenes into wild mosquito populations. We discuss the possibility of optimizing this system and the impetus to do so. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.
Virtanen, Harri
2013-11-01
The paper discusses negative individuation and the hero myth as developmental concepts. It is suggested that in negative individuation healthy psychological development is hindered and goes astray. Aggression then becomes the central psychic system. Repressed anger is the core element in psychopathic narcissism (Diamond) and malignant narcissism (Kernberg). Both Diamond and Kernberg extend narcissistic personality structure to antisocial, psychopathic personality in an effort to better understand extreme violence. According to Freud, love (libido) and hate (the death drive) are the major motivational systems in the human psyche. In contrast to Freud, Jung sees libido as a life force in general, not simply as a sexual drive. Jung writes about evil and the shadow but does not present a comprehensive theory of the negative development of an individual's life. The concept of negative individuation connects the shadow and the death drive with psychopathology, psychiatry and psychotherapy. In this paper, I explore these concepts in the light of contemporary affect theory according to Kernberg. I also ask how ideology is tied to extreme violence and how it is possible that narcissistic personality structures can lead to such radically different outcomes as were manifested in the lives of Anders Behring Breivik and Steve Jobs. © 2013, The Society of Analytical Psychology.
Practical and generalizable architecture for an intelligent tutoring system
NASA Astrophysics Data System (ADS)
Kaplan, Randy M.; Trenholm, Harriet
1993-03-01
In this paper we describe an intelligent tutoring system (ITS) called HYDRIVE (hydraulics interactive video experience). This system is built using several novel approaches to intelligent tutoring. The underlying rationale for HYDRIVE is based on the results of a cognitive task analysis. The reasoning component of the system makes extensive use of a hierarchical knowledge representation. Reasoning within the system is accomplished using a logic-based approach and is linked to a highly interactive interface using multimedia. The knowledge representation contains information that drives the multimedia elements of the system, and the reasoning components select the appropriate information to assess student knowledge or guide the student at any particular moment. As this system will be deployed throughout the Air Force maintenance function, the implementation platform is the IBM PC.
Irdis: A Digital Scene Storage And Processing System For Hardware-In-The-Loop Missile Testing
NASA Astrophysics Data System (ADS)
Sedlar, Michael F.; Griffith, Jerry A.
1988-07-01
This paper describes the implementation of a Seeker Evaluation and Test Simulation (SETS) Facility at Eglin Air Force Base. This facility will be used to evaluate imaging infrared (IIR) guided weapon systems by performing various types of laboratory tests. One such test is termed Hardware-in-the-Loop (HIL) simulation (Figure 1) in which the actual flight of a weapon system is simulated as closely as possible in the laboratory. As shown in the figure, there are four major elements in the HIL test environment; the weapon/sensor combination, an aerodynamic simulator, an imagery controller, and an infrared imagery system. The paper concentrates on the approaches and methodologies used in the imagery controller and infrared imaging system elements for generating scene information. For procurement purposes, these two elements have been combined into an Infrared Digital Injection System (IRDIS) which provides scene storage, processing, and output interface to drive a radiometric display device or to directly inject digital video into the weapon system (bypassing the sensor). The paper describes in detail how standard and custom image processing functions have been combined with off-the-shelf mass storage and computing devices to produce a system which provides high sample rates (greater than 90 Hz), a large terrain database, high weapon rates of change, and multiple independent targets. A photo based approach has been used to maximize terrain and target fidelity, thus providing a rich and complex scene for weapon/tracker evaluation.
Hedonic Homeostatic Dysregulation as a Driver of Drug-Seeking Behavior
Koob, George F.
2009-01-01
Drug addiction can be defined by a compulsion to seek and take drug and loss of control in limiting intake, and the excessive drug taking derives from multiple motivational mechanisms. One such mechanism is the emergence of a negative emotional state when access to the drug is prevented, reflecting hedonic homeostatic dysregulation. Excessive drug taking then results in part via the construct of negative reinforcement. The negative emotional state that drives such negative reinforcement is hypothesized to derive from dysregulation of key neurochemical elements involved in reward and stress within basal forebrain structures, including the ventral striatum and extended amygdala. Specific neurochemical elements in these structures include not only decreases in reward neurotransmission, such as decreases in dopamine and opioid peptide function in the ventral striatum, but also recruitment of brain stress systems, such as corticotropin-releasing factor (CRF), in the extended amygdala. Chronic exposure or extended access to self-administration of all major drugs of abuse produces during abstinence increases in reward thresholds, increases in aversive anxiety-like responses, increases in extracellular levels of CRF in the central nucleus of the amygdala, and increases in drug self-administration. CRF receptor antagonists block excessive drug intake produced by dependence. A combination of decreased reward system function and increased brain stress response system function is hypothesized to be responsible for hedonic homeostatic dysregulation that drives drug seeking behavior in dependence. Such hedonic dysregulation is hypothesized to extend into protracted abstinence to provide a residual negative emotional state that enhances the salience of cues eliciting drug seeking and relapse. PMID:20054425
Neurobiological Substrates for the Dark Side of Compulsivity in Addiction
Koob, George F.
2009-01-01
Drug addiction can be defined by a compulsion to seek and take drug, loss of control in limiting intake, and the emergence of a negative emotional state when access to the drug is prevented. Drug addiction impacts multiple motivational mechanisms and can be conceptualized as a disorder that progresses from impulsivity (positive reinforcement) to compulsivity (negative reinforcement). The construct of negative reinforcement is defined as drug taking that alleviates a negative emotional state. The negative emotional state that drives such negative reinforcement is hypothesized to derive from dysregulation of key neurochemical elements involved in reward and stress within the basal forebrain structures involving the ventral striatum and extended amygdala. Specific neurochemical elements in these structures include not only decreases in reward neurotransmission, such as decreases in dopamine and opioid peptide function in the ventral striatum, but also recruitment of brain stress systems, such as corticotropin-releasing factor (CRF), in the extended amygdala. Acute withdrawal from all major drugs of abuse produces increases in reward thresholds, increases in anxiety-like responses, and increases in extracellular levels of CRF in the central nucleus of the amygdala. CRF receptor antagonists also block excessive drug intake produced by dependence. A brain stress response system is hypothesized to be activated by acute excessive drug intake, to be sensitized during repeated withdrawal, to persist into protracted abstinence, and to contribute to the compulsivity of addiction. Other components of brain stress systems in the extended amygdala that interact with CRF and may contribute to the negative motivational state of withdrawal include norepinephrine, dynorphin, and neuropeptide Y. The combination of loss of reward function and recruitment of brain stress systems provides a powerful neurochemical basis for a negative emotional state that is responsible for the negative reinforcement driving, at least in part, the compulsivity of addiction. PMID:18725236
Hardware system of X-wave generator with simple driving pulses
NASA Astrophysics Data System (ADS)
Li, Xu; Li, Yaqin; Xiao, Feng; Ding, Mingyue; Yuchi, Ming
2013-03-01
The limited diffraction beams such as X-wave have the properties of larger depth of field. Thus, it has the potential to generate ultra-high frame rate ultrasound images. However, in practice, the real-time generation of X-wave ultrasonic field requires complex and high-cost system, especially the precise and specific voltage time distribution part for the excitation of each distinct array element. In order to simplify the hardware realization of X-wave, based on the previous works, X-wave excitation signals were decomposed and expressed as the superposition of a group of simple driving pulses, such as rectangular and triangular waves. The hardware system for the X-wave generator was also designed. The generator consists of a computer for communication with the circuit, universal serial bus (USB) based micro-controller unit (MCU) for data transmission, field programmable gate array (FPGA) based Direct Digital Synthesizer(DDS), 12-bit digital-to-analog (D/A) converter and a two stage amplifier.The hardware simulation results show that the designed system can generate the waveforms at different radius approximating the theoretical X-wave excitations with a maximum error of 0.49% triggered by the quantification of amplitude data.
DOT National Transportation Integrated Search
2016-09-01
One of the most important elements of vehicle-pedestrian collisions emanates from : distracted driving. Our mandate in the present project sub-element was to examine and : evaluate such distraction as it affects the latter collision configuration. : ...
[Motor vehicle driving and diabetes mellitus - medical aspects].
Brož, Jan; Kriváňová, Lenka Syčová; Fedáková, Zuzana; Petrosyan, Lilit; Kvapil, Milan; Polák, Jan
2016-03-01
Diabetes mellitus is a disease which may affect the eligibility to hold a driving license and increase the risk of a road accident. Hypoglycemia while driving is considered to be the most risky situation, with diabetes increasing the mentioned risk for instance due to impaired vision in the case of possible retinopathy. The group of drivers with diabetes being at the greatest risk as to accidents are those with a case history of severe hypoglycemia or hypoglycemia occurred while driving, or possibly of a road accident. Measuring glycaemia before driving and their knowledge how to prevent and treat hypoglycemia - those are the two crucial preventive elements indispensable for insulin treated diabetes patients in order to secure safe road traffic.
Laser driving and data processing concept for mobile trace gas sensing: Design and implementation
NASA Astrophysics Data System (ADS)
Liu, Chang; Tuzson, Béla; Scheidegger, Philipp; Looser, Herbert; Bereiter, Bernhard; Graf, Manuel; Hundt, Morten; Aseev, Oleg; Maas, Deran; Emmenegger, Lukas
2018-06-01
High precision mobile sensing of multi-species gases is greatly demanded in a wide range of applications. Although quantum cascade laser absorption spectroscopy demonstrates excellent field-deployment capabilities for gas sensing, the implementation of this measurement technique into sensor-like portable instrumentation still remains challenging. In this paper, two crucial elements, the laser driving and data acquisition electronics, are addressed. Therefore, we exploit the benefits of the time-division multiplexed intermittent continuous wave driving concept and the real-time signal pre-processing capabilities of a commercial System-on-Chip (SoC, Red Pitaya). We describe a re-designed current driver that offers a universal solution for operating a wide range of multi-wavelength quantum cascade laser device types and allows stacking for the purpose of multiple laser configurations. Its adaptation to the various driving situations is enabled by numerous field programmable gate array (FPGA) functionalities that were developed on the SoC, such as flexible generation of a large variety of synchronized trigger signals and digital inputs/outputs (DIOs). The same SoC is used to sample the spectroscopic signal at rates up to 125 MS/s with 14-bit resolution. Additional FPGA functionalities were implemented to enable on-board averaging of consecutive spectral scans in real-time, resulting in optimized memory bandwidth and hardware resource utilisation and autonomous system operation. Thus, we demonstrate how a cost-effective, compact, and commercial SoC can successfully be adapted to obtain a fully operational research-grade laser spectrometer. The overall system performance was examined in a spectroscopic setup by analyzing low pressure absorption features of CO2 at 4.3 μm.
Emergence of an enslaved phononic bandgap in a non-equilibrium pseudo-crystal.
Bachelard, Nicolas; Ropp, Chad; Dubois, Marc; Zhao, Rongkuo; Wang, Yuan; Zhang, Xiang
2017-08-01
Material systems that reside far from thermodynamic equilibrium have the potential to exhibit dynamic properties and behaviours resembling those of living organisms. Here we realize a non-equilibrium material characterized by a bandgap whose edge is enslaved to the wavelength of an external coherent drive. The structure dynamically self-assembles into an unconventional pseudo-crystal geometry that equally distributes momentum across elements. The emergent bandgap is bestowed with lifelike properties, such as the ability to self-heal to perturbations and adapt to sudden changes in the drive. We derive an exact analytical solution for both the spatial organization and the bandgap features, revealing the mechanism for enslavement. This work presents a framework for conceiving lifelike non-equilibrium materials and emphasizes the potential for the dynamic imprinting of material properties through external degrees of freedom.
Emergence of an enslaved phononic bandgap in a non-equilibrium pseudo-crystal
NASA Astrophysics Data System (ADS)
Bachelard, Nicolas; Ropp, Chad; Dubois, Marc; Zhao, Rongkuo; Wang, Yuan; Zhang, Xiang
2017-08-01
Material systems that reside far from thermodynamic equilibrium have the potential to exhibit dynamic properties and behaviours resembling those of living organisms. Here we realize a non-equilibrium material characterized by a bandgap whose edge is enslaved to the wavelength of an external coherent drive. The structure dynamically self-assembles into an unconventional pseudo-crystal geometry that equally distributes momentum across elements. The emergent bandgap is bestowed with lifelike properties, such as the ability to self-heal to perturbations and adapt to sudden changes in the drive. We derive an exact analytical solution for both the spatial organization and the bandgap features, revealing the mechanism for enslavement. This work presents a framework for conceiving lifelike non-equilibrium materials and emphasizes the potential for the dynamic imprinting of material properties through external degrees of freedom.
Searching for a Spore killer: A meiotic drive element in Neurospora fungi
USDA-ARS?s Scientific Manuscript database
Mendelian inheritance predicts that different alleles of the same gene will have an equal chance of being transmitted to the next generation. However, meiotic drive is a phenomenon where certain alleles evolve the ability to bias transmission in their own favor. In this study we are investigating a ...
Non-linear dynamic analysis of geared systems. Final Report Ph.D. Thesis
NASA Technical Reports Server (NTRS)
Singh, Rajendra; Houser, Donald R.; Kahraman, Ahmet
1990-01-01
Under driving conditions, a typical geared system may be subjected to large dynamic loads. Also, the vibration level of the geared system is directly related to the noise radiated from the gear box. The steady state dynamic behavior of the system is examined in order to design reliable and quiet transmissions. The scope is limited to a system containing a spur gear pair with backlash and periodically time varying mesh stiffness, and rolling element bearings with clearance type nonlinearities. The internal static transmission error at the gear mesh, which is of importance from high frequency noise and vibration control view point, is considered in the formulation in sinusoidal or periodic form. A dynamic finite element model of the linear time invariant (LTI) system is developed. Effects of several system parameters, such as torsional and transverse flexibilities of the shafts and prime mover/load inertias, on free and forced vibration characteristics are investigated. Several reduced order LTI models are developed and validated by comparing their eigen solutions with the finite element model results. Using the reduced order formulations, a three degree of freedom dynamic model is developed which includes nonlinearities associated with radical clearances in the radial rolling element bearings, backlash between a spur gear pair and periodically varying gear mesh stiffness. As a limiting case, a single degree of freedom model of the spur gear pair with backlash is considered and mathematical conditions for tooth separation and back collision are defined. Both digital simulation technique and analytical models such as method of harmonic balance and the method of multiple scales were used to develop the steady state frequency response characteristics for various nonlinear and/or time varying cases.
High performance VLSI telemetry data systems
NASA Technical Reports Server (NTRS)
Chesney, J.; Speciale, N.; Horner, W.; Sabia, S.
1990-01-01
NASA's deployment of major space complexes such as Space Station Freedom (SSF) and the Earth Observing System (EOS) will demand increased functionality and performance from ground based telemetry acquisition systems well above current system capabilities. Adaptation of space telemetry data transport and processing standards such as those specified by the Consultative Committee for Space Data Systems (CCSDS) standards and those required for commercial ground distribution of telemetry data, will drive these functional and performance requirements. In addition, budget limitations will force the requirement for higher modularity, flexibility, and interchangeability at lower cost in new ground telemetry data system elements. At NASA's Goddard Space Flight Center (GSFC), the design and development of generic ground telemetry data system elements, over the last five years, has resulted in significant solutions to these problems. This solution, referred to as the functional components approach includes both hardware and software components ready for end user application. The hardware functional components consist of modern data flow architectures utilizing Application Specific Integrated Circuits (ASIC's) developed specifically to support NASA's telemetry data systems needs and designed to meet a range of data rate requirements up to 300 Mbps. Real-time operating system software components support both embedded local software intelligence, and overall system control, status, processing, and interface requirements. These components, hardware and software, form the superstructure upon which project specific elements are added to complete a telemetry ground data system installation. This paper describes the functional components approach, some specific component examples, and a project example of the evolution from VLSI component, to basic board level functional component, to integrated telemetry data system.
NASA Astrophysics Data System (ADS)
He, Liangguo; Chu, Yuheng; Hao, Sai; Zhao, Xiaoyong; Dong, Yuge; Wang, Yong
2018-05-01
A novel, single-phase, harmonic-driven, inertial piezoelectric linear motor using an automatic clamping mechanism was designed, fabricated, and tested to reduce the sliding friction and simplify the drive mechanism and power supply control of the inertial motor. A piezoelectric bimorph and a flexible hinge were connected in series to form the automatic clamping mechanism. The automatic clamping mechanism was used as the driving and clamping elements. A dynamic simulation by Simulink was performed to prove the feasibility of the motor. The finite element method software COMSOL was used to design the structure of the motor. An experimental setup was built to validate the working principle and evaluate the performance of the motor. The prototype motor outputted a no-load velocity of 3.178 mm/s at a voltage of 220 Vp-p and a maximum traction force of 4.25 N under a preload force of 8 N. The minimum resolution of 1.14 μm was achieved at a driving frequency of 74 Hz, a driving voltage of 50 Vp-p, and a preload force of 0 N.
Warren, Ian A; Naville, Magali; Chalopin, Domitille; Levin, Perrine; Berger, Chloé Suzanne; Galiana, Delphine; Volff, Jean-Nicolas
2015-09-01
Since their discovery, a growing body of evidence has emerged demonstrating that transposable elements are important drivers of species diversity. These mobile elements exhibit a great variety in structure, size and mechanisms of transposition, making them important putative actors in organism evolution. The vertebrates represent a highly diverse and successful lineage that has adapted to a wide range of different environments. These animals also possess a rich repertoire of transposable elements, with highly diverse content between lineages and even between species. Here, we review how transposable elements are driving genomic diversity and lineage-specific innovation within vertebrates. We discuss the large differences in TE content between different vertebrate groups and then go on to look at how they affect organisms at a variety of levels: from the structure of chromosomes to their involvement in the regulation of gene expression, as well as in the formation and evolution of non-coding RNAs and protein-coding genes. In the process of doing this, we highlight how transposable elements have been involved in the evolution of some of the key innovations observed within the vertebrate lineage, driving the group's diversity and success.
A Framework for Integrated Component and System Analyses of Instabilities
NASA Technical Reports Server (NTRS)
Ahuja, Vineet; Erwin, James; Arunajatesan, Srinivasan; Cattafesta, Lou; Liu, Fei
2010-01-01
Instabilities associated with fluid handling and operation in liquid rocket propulsion systems and test facilities usually manifest themselves as structural vibrations or some form of structural damage. While the source of the instability is directly related to the performance of a component such as a turbopump, valve or a flow control element, the associated pressure fluctuations as they propagate through the system have the potential to amplify and resonate with natural modes of the structural elements and components of the system. In this paper, the authors have developed an innovative multi-level approach that involves analysis at the component and systems level. The primary source of the unsteadiness is modeled with a high-fidelity hybrid RANS/LES based CFD methodology that has been previously used to study instabilities in feed systems. This high fidelity approach is used to quantify the instability and understand the physics associated with the instability. System response to the driving instability is determined through a transfer matrix approach wherein the incoming and outgoing pressure and velocity fluctuations are related through a transfer (or transmission) matrix. The coefficients of the transfer matrix for each component (i.e. valve, pipe, orifice etc.) are individually derived from the flow physics associated with the component. A demonstration case representing a test loop/test facility comprised of a network of elements is constructed with the transfer matrix approach and the amplification of modes analyzed as the instability propagates through the test loop.
Operational Loopwheel Suspension System for Mars Rover Demonstration Model
NASA Technical Reports Server (NTRS)
Trautwein, W.; Robinson, G. D.
1978-01-01
The loopwheel (or elastic loop) mobility concept, appears to be uniquely qualified to provide a high degree of mobility at low weight and stowage requirements for the next Mars mission now in the early planning stage. Traction elements compatible with sterilization and Mars surface environmental constraints were designed and are compatible with the rover mass, range and stowage requirements of JPL's point design Mars rover. In order to save cost, the loopwheel suspensions for the demonstration model were made of S-glass/epoxy instead of titanium, alloy specified for flight units. The load carrying fiberglass loop core is covered by a rubber tread on the outside. Reinforced rubber gear belts bonded along the inside edges provide positive engagement and transmission drive torques. A 12 Vdc drive motor with a 167:1 gear head is installed in the payload section of the hull. A chain drive transmits the motor power to the rear sprocket in the demonstration model, whereas future flight units would be directly driven by brushless hub motors within each sprocket and independent four-leg height control.
Improving the accuracy of walking piezo motors.
den Heijer, M; Fokkema, V; Saedi, A; Schakel, P; Rost, M J
2014-05-01
Many application areas require ultraprecise, stiff, and compact actuator systems with a high positioning resolution in combination with a large range as well as a high holding and pushing force. One promising solution to meet these conflicting requirements is a walking piezo motor that works with two pairs of piezo elements such that the movement is taken over by one pair, once the other pair reaches its maximum travel distance. A resolution in the pm-range can be achieved, if operating the motor within the travel range of one piezo pair. However, applying the typical walking drive signals, we measure jumps in the displacement up to 2.4 μm, when the movement is given over from one piezo pair to the other. We analyze the reason for these large jumps and propose improved drive signals. The implementation of our new drive signals reduces the jumps to less than 42 nm and makes the motor ideally suitable to operate as a coarse approach motor in an ultra-high vacuum scanning tunneling microscope. The rigidity of the motor is reflected in its high pushing force of 6.4 N.
General scaling relations for locomotion in granular media
NASA Astrophysics Data System (ADS)
Slonaker, James; Motley, D. Carrington; Zhang, Qiong; Townsend, Stephen; Senatore, Carmine; Iagnemma, Karl; Kamrin, Ken
2017-05-01
Inspired by dynamic similarity in fluid systems, we have derived a general dimensionless form for locomotion in granular materials, which is validated in experiments and discrete element method (DEM) simulations. The form instructs how to scale size, mass, and driving parameters in order to relate dynamic behaviors of different locomotors in the same granular media. The scaling can be derived by assuming intrusion forces arise from resistive force theory or equivalently by assuming the granular material behaves as a continuum obeying a frictional yield criterion. The scalings are experimentally confirmed using pairs of wheels of various shapes and sizes under many driving conditions in a common sand bed. We discuss why the two models provide such a robust set of scaling laws even though they neglect a number of the complexities of granular rheology. Motivated by potential extraplanetary applications, the dimensionless form also implies a way to predict wheel performance in one ambient gravity based on tests in a different ambient gravity. We confirm this using DEM simulations, which show that scaling relations are satisfied over an array of driving modes even when gravity differs between scaled tests.
7th Annual Systems Biology Symposium: Systems Biology and Engineering
DOE Office of Scientific and Technical Information (OSTI.GOV)
Galitski, Timothy P.
2008-04-01
Systems biology recognizes the complex multi-scale organization of biological systems, from molecules to ecosystems. The International Symposium on Systems Biology has been hosted by the Institute for Systems Biology in Seattle, Washington, since 2002. The annual two-day event gathers the most influential researchers transforming biology into an integrative discipline investingating complex systems. Engineering and application of new technology is a central element of systems biology. Genome-scale, or very small-scale, biological questions drive the enigneering of new technologies, which enable new modes of experimentation and computational analysis, leading to new biological insights and questions. Concepts and analytical methods in engineering aremore » now finding direct applications in biology. Therefore, the 2008 Symposium, funded in partnership with the Department of Energy, featured global leaders in "Systems Biology and Engineering."« less
The Trans-Rocky Mountain Fault System - A Fundamental Precambrian Strike-Slip System
Sims, P.K.
2009-01-01
Recognition of a major Precambrian continental-scale, two-stage conjugate strike-slip fault system - here designated as the Trans-Rocky Mountain fault system - provides new insights into the architecture of the North American continent. The fault system consists chiefly of steep linear to curvilinear, en echelon, braided and branching ductile-brittle shears and faults, and local coeval en echelon folds of northwest strike, that cut indiscriminately across both Proterozoic and Archean cratonic elements. The fault system formed during late stages of two distinct tectonic episodes: Neoarchean and Paleoproterozoic orogenies at about 2.70 and 1.70 billion years (Ga). In the Archean Superior province, the fault system formed (about 2.70-2.65 Ga) during a late stage of the main deformation that involved oblique shortening (dextral transpression) across the region and progressed from crystal-plastic to ductile-brittle deformation. In Paleoproterozoic terranes, the fault system formed about 1.70 Ga, shortly following amalgamation of Paleoproterozoic and Archean terranes and the main Paleoproterozoic plastic-fabric-producing events in the protocontinent, chiefly during sinistral transpression. The postulated driving force for the fault system is subcontinental mantle deformation, the bottom-driven deformation of previous investigators. This model, based on seismic anisotropy, invokes mechanical coupling and subsequent shear between the lithosphere and the asthenosphere such that a major driving force for plate motion is deep-mantle flow.
Advancements for continuous miners
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fiscor, S.
2007-06-15
Design changes and new technology make the modern continuous miner more user friendly. Two of the major manufacturers, Joy Mining Machinery and DBT, both based near Pittsburgh, PA, USA, have recently acquired other OEMs to offer a greater product line. Joy's biggest development in terms of improving cutting time is the FACEBOSS Control System which has an operator assistance element and Joy Surface Reporting Software (JSRP). Joy's WetHead continuous miners have excellent performance. DBT is researching ways to make the machines more reliable with new drive systems. It has also been experimenting with water sprays to improve dust suppression. 4more » photos.« less
Animal emotions, behaviour and the promotion of positive welfare states.
Mellor, D J
2012-01-01
This paper presents a rationale that may significantly boost the drive to promote positive welfare states in animals. The rationale is based largely, but not exclusively, on an experimentally supported neuropsychological understanding of relationships between emotions and behaviour, an understanding that has not yet been incorporated into animal welfare science thinking. Reference is made to major elements of the neural/cognitive foundations of motivational drives that energise and direct particular behaviours and their related subjective or emotional experiences. These experiences are generated in part by sensory inputs that reflect the animal's internal functional state and by neural processing linked to the animal's perception of its external circumstances. The integrated subjective or emotional outcome of these inputs corresponds to the animal's welfare status. The internally generated subjective experiences represent motivational urges or drives that are predominantly negative and include breathlessness, thirst, hunger and pain. They are generated by, and elicit specific behaviours designed to correct, imbalances in the animal's internal functional state. Externally generated subjective experiences are said to be integral to the operation of interacting 'action-orientated systems' that give rise to particular behaviours and their negative or positive emotional contents. These action-orientated systems, described in neuropsychological terms, give rise to negative emotions that include fear, anger and panic, and positive emotions that include comfort, vitality, euphoria and playfulness. It is argued that early thinking about animal welfare management focused mainly on minimising disturbances to the internal functional states that generate associated unpleasant motivational urges or drives. This strategy produced animal welfare benefits, but at best it could only lift a poor net welfare status to a neutral one. In contrast, strategies designed to manipulate the emotional action-orientated systems have the potential to replace the negative emotions generated within those systems with positive ones, and thereby may lift a poor net state of welfare beyond the neutral point to a net positive state. It is hoped that the analysis presented here will enhance the drive to promote positive welfare states by providing cogent and convincing neuropsychological support for the formulation of additional, more directed welfare code recommendations and standards that focus on the animal's behaviour.
Application of traction drives as servo mechanisms
NASA Technical Reports Server (NTRS)
Loewenthal, S. H.; Rohn, D. A.; Steinetz, B. M.
1985-01-01
The suitability of traction drives for a wide class of aerospace control mechanisms is examined. Potential applications include antenna or solar array drive positioners, robotic joints, control moment gyro (CMG) actuators and propeller pitch change mechanisms. In these and similar applications the zero backlash, high torsional stiffness, low hysteresis and torque ripple characteristics of traction drives are of particular interest, as is the ability to run without liquid lubrication in certain cases. Wear and fatigue considerations for wet and dry operation are examined along with the tribological performance of several promising self lubricating polymers for traction contracts. The speed regulation capabilities of variable ratio traction drives are reviewed. A torsional stiffness analysis described suggests that traction contacts are relatively stiff compared to gears and are significantly stiffer than the other structural elements in the prototype CMG traction drive analyzed. Discussion is also given of an advanced turboprop propeller pitch change mechanism that incorporates a traction drive.
Hu, Jiangbi; Wang, Ronghua
2018-02-17
Guaranteeing a safe and comfortable driving workload can contribute to reducing traffic injuries. In order to provide safe and comfortable threshold values, this study attempted to classify driving workload from the aspects of human factors mainly affected by highway geometric conditions and to determine the thresholds of different workload classifications. This article stated a hypothesis that the values of driver workload change within a certain range. Driving workload scales were stated based on a comprehensive literature review. Through comparative analysis of different psychophysiological measures, heart rate variability (HRV) was chosen as the representative measure for quantifying driving workload by field experiments. Seventy-two participants (36 car drivers and 36 large truck drivers) and 6 highways with different geometric designs were selected to conduct field experiments. A wearable wireless dynamic multiparameter physiological detector (KF-2) was employed to detect physiological data that were simultaneously correlated to the speed changes recorded by a Global Positioning System (GPS) (testing time, driving speeds, running track, and distance). Through performing statistical analyses, including the distribution of HRV during the flat, straight segments and P-P plots of modified HRV, a driving workload calculation model was proposed. Integrating driving workload scales with values, the threshold of each scale of driving workload was determined by classification and regression tree (CART) algorithms. The driving workload calculation model was suitable for driving speeds in the range of 40 to 120 km/h. The experimental data of 72 participants revealed that driving workload had a significant effect on modified HRV, revealing a change in driving speed. When the driving speed was between 100 and 120 km/h, drivers showed an apparent increase in the corresponding modified HRV. The threshold value of the normal driving workload K was between -0.0011 and 0.056 for a car driver and between -0.00086 and 0.067 for a truck driver. Heart rate variability was a direct and effective index for measuring driving workload despite being affected by multiple highway alignment elements. The driving workload model and the thresholds of driving workload classifications can be used to evaluate the quality of highway geometric design. A higher quality of highway geometric design could keep driving workload within a safer and more comfortable range. This study provided insight into reducing traffic injuries from the perspective of disciplinary integration of highway engineering and human factor engineering.
New Adventures in Screencasting
ERIC Educational Resources Information Center
Flynn, Stephen X.
2013-01-01
There are universal elements to great videos and games that drive large audiences: beautiful cinematography and graphics, engaging and purposeful screenplays and storylines, unforgettable soundtracks, and a brand name that makes viewers and players want to return for more. Libraries can, and should, employ these elements in their own videos to…
Sociocultural Theory, the L2 Writing Process, and Google Drive: Strange Bedfellows?
ERIC Educational Resources Information Center
Slavkov, Nikolay
2015-01-01
As familiar and widely used elements of second language pedagogy that can be leveraged in interesting new ways through the use of digital technology. The focus is on a set of affordances offered by Google Drive, a popular online storage and document-sharing technology. On the assumption that dynamic collaboration with peers, teacher feedback, and…
ERIC Educational Resources Information Center
Mueller, Robin Alison
2015-01-01
Strategic planning is a common practice at higher education institutions. Furthermore, it is assumed that identifying organizational values is an essential part of the planning process. Values are often construed as foundational elements of strategic thinking that serve to "drive the plan". However, there is little conceptual or applied…
Dynamics of binary and planetary-system interaction with disks - Eccentricity changes
NASA Technical Reports Server (NTRS)
Atrymowicz, Pawel
1992-01-01
Protostellar and protoplanetary systems, as well as merging galactic nuclei, often interact tidally and resonantly with the astrophysical disks via gravity. Underlying our understanding of the formation processes of stars, planets, and some galaxies is a dynamical theory of such interactions. Its main goals are to determine the geometry of the binary-disk system and, through the torque calculations, the rate of change of orbital elements of the components. We present some recent developments in this field concentrating on eccentricity driving mechanisms in protoplanetary and protobinary systems. In those two types of systems the result of the interaction is opposite. A small body embedded in a disk suffers a decrease of orbital eccentricity, whereas newly formed binary stars surrounded by protostellar disks may undergo a significant orbital evolution increasing their eccentricities.
Diagnosing oceanic nutrient deficiency
2016-01-01
The supply of a range of nutrient elements to surface waters is an important driver of oceanic production and the subsequent linked cycling of the nutrients and carbon. Relative deficiencies of different nutrients with respect to biological requirements, within both surface and internal water masses, can be both a key indicator and driver of the potential for these nutrients to become limiting for the production of new organic material in the upper ocean. The availability of high-quality, full-depth and global-scale datasets on the concentrations of a wide range of both macro- and micro-nutrients produced through the international GEOTRACES programme provides the potential for estimation of multi-element deficiencies at unprecedented scales. Resultant coherent large-scale patterns in diagnosed deficiency can be linked to the interacting physical–chemical–biological processes which drive upper ocean nutrient biogeochemistry. Calculations of ranked deficiencies across multiple elements further highlight important remaining uncertainties in the stoichiometric plasticity of nutrient ratios within oceanic microbial systems and caveats with regards to linkages to upper ocean nutrient limitation. This article is part of the themed issue ‘Biological and climatic impacts of ocean trace element chemistry’. PMID:29035255
Diagnosing oceanic nutrient deficiency
NASA Astrophysics Data System (ADS)
Moore, C. Mark
2016-11-01
The supply of a range of nutrient elements to surface waters is an important driver of oceanic production and the subsequent linked cycling of the nutrients and carbon. Relative deficiencies of different nutrients with respect to biological requirements, within both surface and internal water masses, can be both a key indicator and driver of the potential for these nutrients to become limiting for the production of new organic material in the upper ocean. The availability of high-quality, full-depth and global-scale datasets on the concentrations of a wide range of both macro- and micro-nutrients produced through the international GEOTRACES programme provides the potential for estimation of multi-element deficiencies at unprecedented scales. Resultant coherent large-scale patterns in diagnosed deficiency can be linked to the interacting physical-chemical-biological processes which drive upper ocean nutrient biogeochemistry. Calculations of ranked deficiencies across multiple elements further highlight important remaining uncertainties in the stoichiometric plasticity of nutrient ratios within oceanic microbial systems and caveats with regards to linkages to upper ocean nutrient limitation. This article is part of the themed issue 'Biological and climatic impacts of ocean trace element chemistry'.
Two position optical element actuator device
Holdener, Fred R.; Boyd, Robert D.
2002-01-01
The present invention is a two position optical element actuator device utilizing a powered means to hold an actuation arm, to which an optical element is attached, in a first position. A non-powered means drives the actuation arm to a second position, when the powered means ceases to receive power. The optical element may be a electromagnetic (EM) radiation or particle source, an instrument, or EM radiation or particle transmissive, reflective or absorptive elements. A bearing is used to transfer motion and smoothly transition the actuation arm from the first to second position.
Richard, Christian M; Wright, Richard D; Ee, Cheryl; Prime, Steven L; Shimizu, Yujiro; Vavrik, John
2002-01-01
The effect of a concurrent auditory task on visual search was investigated using an image-flicker technique. Participants were undergraduate university students with normal or corrected-to-normal vision who searched for changes in images of driving scenes that involved either driving-related (e.g., traffic light) or driving-unrelated (e.g., mailbox) scene elements. The results indicated that response times were significantly slower if the search was accompanied by a concurrent auditory task. In addition, slower overall responses to scenes involving driving-unrelated changes suggest that the underlying process affected by the concurrent auditory task is strategic in nature. These results were interpreted in terms of their implications for using a cellular telephone while driving. Actual or potential applications of this research include the development of safer in-vehicle communication devices.
Study on heat pipe assisted thermoelectric power generation system from exhaust gas
NASA Astrophysics Data System (ADS)
Chi, Ri-Guang; Park, Jong-Chan; Rhi, Seok-Ho; Lee, Kye-Bock
2017-11-01
Currently, most fuel consumed by vehicles is released to the environment as thermal energy through the exhaust pipe. Environmentally friendly vehicle technology needs new methods to increase the recycling efficiency of waste exhaust thermal energy. The present study investigated how to improve the maximum power output of a TEG (Thermoelectric generator) system assisted with a heat pipe. Conventionally, the driving energy efficiency of an internal combustion engine is approximately less than 35%. TEG with Seebeck elements is a new idea for recycling waste exhaust heat energy. The TEG system can efficiently utilize low temperature waste heat, such as industrial waste heat and solar energy. In addition, the heat pipe can transfer heat from the automobile's exhaust gas to a TEG. To improve the efficiency of the thermal power generation system with a heat pipe, effects of various parameters, such as inclination angle, charged amount of the heat pipe, condenser temperature, and size of the TEM (thermoelectric element), were investigated. Experimental studies, CFD simulation, and the theoretical approach to thermoelectric modules were carried out, and the TEG system with heat pipe (15-20% charged, 20°-30° inclined configuration) showed the best performance.
Closed-loop helium circulation system for actuation of a continuously operating heart catheter pump.
Karabegovic, Alen; Hinteregger, Markus; Janeczek, Christoph; Mohl, Werner; Gföhler, Margit
2017-06-09
Currently available, pneumatic-based medical devices are operated using closed-loop pulsatile or open continuous systems. Medical devices utilizing gases with a low atomic number in a continuous closed loop stream have not been documented to date. This work presents the construction of a portable helium circulation addressing the need for actuating a novel, pneumatically operated catheter pump. The design of its control system puts emphasis on the performance, safety and low running cost of the catheter pump. Static and dynamic characteristics of individual elements in the circulation are analyzed to ensure a proper operation of the system. The pneumatic circulation maximizes the working range of the drive unit inside the catheter pump while reducing the total size and noise production.Separate flow and pressure controllers position the turbine's working point into the stable region of the pressure creation element. A subsystem for rapid gas evacuation significantly decreases the duration of helium removal after a leak, reaching subatmospheric pressure in the intracorporeal catheter within several milliseconds. The system presented in the study offers an easy control of helium mass flow while ensuring stable behavior of its internal components.
Bringing Science Research into Secondary Schools
ERIC Educational Resources Information Center
Allwood, Dan A.; Dean, Julian; Bryan, Matthew T.; Baker, Alan
2009-01-01
Finite element modelling software has been used to allow secondary school students to study nanoscale magnetic materials for hard drive recording applications. The students were introduced to the basic concepts of finite element modelling using a freely available internet game before modelling the magnetization reversal of single magnetic grains.…
Using Competencies to Improve School Turnaround Principal Success
ERIC Educational Resources Information Center
Steiner, Lucy; Hassel, Emily Ayscue
2011-01-01
This paper aims first to shed light on one element of leadership: the characteristics--or "competencies"--of turnaround leaders who succeed in driving rapid, dramatic change. Second, it recounts the elements of support that districts must provide these leaders to enable and sustain a portfolio of successful school turnarounds.…
Sequencing and molecular dissection of Sk-2 in Neurospora
USDA-ARS?s Scientific Manuscript database
Neurospora Spore killer-2 is a selfish meiotic drive element that kills its non-Sk-2 siblings during sexual sporulation. Although the location of Sk-2 has been mapped to a large recombination-suppressed region of chromosome III, the physical length and exact borders of the element have remained unde...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sethuraman, Latha; Fingersh, Lee J; Dykes, Katherine L
As wind turbine blade diameters and tower height increase to capture more energy in the wind, higher structural loads results in more structural support material increasing the cost of scaling. Weight reductions in the generator transfer to overall cost savings of the system. Additive manufacturing facilitates a design-for-functionality approach, thereby removing traditional manufacturing constraints and labor costs. The most feasible additive manufacturing technology identified for large, direct-drive generators in this study is powder-binder jetting of a sand cast mold. A parametric finite element analysis optimization study is performed, optimizing for mass and deformation. Also, topology optimization is employed for eachmore » parameter-optimized design.The optimized U-beam spoked web design results in a 24 percent reduction in structural mass of the rotor and 60 percent reduction in radial deflection.« less
Multi-functional Electric Module for a Vehicle
NASA Technical Reports Server (NTRS)
Waligora, Thomas M. (Inventor); Fraser-Chanpong, Nathan (Inventor); Figuered, Joshua M. (Inventor); Reed, Ryan (Inventor); Akinyode, Akinjide Akinniyi (Inventor); Spain, Ivan (Inventor); Dawson, Andrew D. (Inventor); Herrera, Eduardo (Inventor); Markee, Mason M. (Inventor); Bluethmann, William J. (Inventor)
2015-01-01
A multi-functional electric module (eModule) is provided for a vehicle having a chassis, a master controller, and a drive wheel having a propulsion-braking module. The eModule includes a steering control assembly, mounting bracket, propulsion control assembly, brake controller, housing, and control arm. The steering control assembly includes a steering motor controlled by steering controllers in response to control signals from the master controller. A mounting feature of the bracket connects to the chassis. The propulsion control assembly and brake controller are in communication with the propulsion-braking module. The control arm connects to the lower portion and contains elements of a suspension system, with the control arm being connectable to the drive wheel via a wheel input/output block. The controllers are responsive to the master controller to control a respective steering, propulsion, and braking function. The steering motor may have a dual-wound stator with windings controlled via the respective steering controllers.
NASA Technical Reports Server (NTRS)
Friesen, F. Q. L.; John, B.; Skinner, C. H.; Roquemore, A. L.; Calle, C. I.
2011-01-01
The ability to manage inventories of carbon, tritium, and high-Z elements in fusion plasmas depends on means for effective dust removal. A dust conveyor, based on a moving electrostatic potential well, was tested with particles of tungsten, carbon, glass and sand. A digital microscope imaged a representative portion of the conveyor, and dust particle size and volume distributions were derived before and after operation. About 10 cu mm volume of carbon and tungsten particles were moved in under 5 seconds. The highest driving amplitude tested of 3 kV was the most effective. The optimal driving frequency was 210 Hz (maximum tested) for tungsten particles, decreasing to below 60 Hz for the larger sand particles. Measurements of particle size and volume distributions after 10 and 100 cycles show the breaking apart of agglomerated carbon, and the change in particle distribution over short timescales 1 s).
Laser Mode Behavior of the Cassini CIRS Fourier Transform Spectrometer at Saturn
NASA Technical Reports Server (NTRS)
Brasunas, John C.
2012-01-01
The CIRS Fourier transform spectrometer aboard the NASA/ESA/ASI Cassini orbiter has been acquiring spectra of the Saturnian system since 2004. The CIRS reference interferometer employs a laser diode to trigger the interferogram sampling. Although the control of laser diode drive current and operating temperature are stringent enough to restrict laser wavelength variation to a small fraction of CIRS finest resolution element, the CIRS instrument does need to be restarted every year or two, at which time it may start in a new laser mode. By monitoring the Mylar absorption features in uncalibrated spectra due to the beam splitter Mylar substrate, it can be shown that these jumps are to adjacent modes and that most of the eight-year operation so far is restricted to three adjacent modes. For a given mode, the wavelength stability appears consistent with the stability of the laser diode drive curren.t and operating temperature.
Characterization of a pneumatic balloon actuator for use in refreshable Braille displays.
Fan, Richard E; Feinman, Adam M; Wottawa, Christopher; King, Chih-Hung; Franco, Miguel L; Dutson, Erik P; Grundfest, Warren S; Culjat, Martin O
2009-01-01
Many existing refreshable Braille display technologies are costly or lack robust performance. A process has been developed to fabricate consistent and reliable pneumatic balloon actuators at low material cost, using a novel manufacturing process. This technique has been adapted for use in refreshable Braille displays that feature low power consumption, ease of manufacture and small form factor. A prototype refreshable cell, conforming to American Braille standards, was developed and tested. The cell was fabricated from molded PDMS to form balloon actuators with a spin-coated silicone film, and fast pneumatic driving elements and an electronic control system were developed to drive the Braille dots. Perceptual testing was performed to determine the feasibility of the approach using a single blind human subject. The subject was able to detect randomized Braille letters rapidly generated by the actuator with 100% character detection accuracy.
Fell, James C.; Todd, Michael; Voas, Robert B.
2011-01-01
Introduction The high crash rate of youthful novice drivers has been recognized for half a century. Over the last decade, graduated driver licensing (GDL) systems, which extend the period of supervised driving and limit the novice’s exposure to higher-risk conditions (such as nighttime driving) has effectively reduced crash involvements of novice drivers. Method This study used data from the Fatality Analysis Reporting System (FARS) and the implementation dates of GDL laws in a state-by-year panel study to evaluate the effectiveness of two key elements of GDL laws: nighttime restrictions and passenger limitations. Results Nighttime restrictions were found to reduce 16- and 17-year-old driver involvements in nighttime fatal crashes by an estimated 10% and 16- and 17-year-old drinking drivers in nighttime fatal crashes by 13%. Passenger restrictions were found to reduce 16- and 17-year-old driver involvements in fatal crashes with teen passengers by an estimated 9%. Conclusions These results confirm the effectiveness of these provisions in GDL systems. Impact on Public Health The results of this study indicate that nighttime restrictions and passenger limitations are very important components of any GDL law. PMID:22017831
Legge, David; Gleeson, Deborah H
2015-07-20
Health reform is the outcome of dispersed policy initiatives in different sectors, at different levels and across time. Policy work which can drive coherent health reform needs to operate across the governance structures as well as the institutions that comprise healthcare systems. Building policy capacity to support health reform calls for clarity regarding the nature of such policy work and the elements of policy capacity involved; and for evidence regarding effective strategies for capacity building. © 2015 by Kerman University of Medical Sciences.
Fuel injection device and method
Carlson, L.W.
1983-12-21
A fuel injection system and method provide for shaping a combustion plume within a combustion chamber to effectively recirculate hot combustion gases for stable combustion conditions while providing symmetrical combustion conditions. Char and molten slag are passed to the outer boundary layer to complete combustion of char while permitting initial substoichiometric combustion in a reductive atmosphere for reducing discharge of nitrogen oxides. Shaping of the plume is accomplished by an axially adjustable pintle which permits apportionment of driving pressure between elements which contribute tangential and those which contribute radial directional components to oxidant flow entering the combustion chamber.
Fuel injection device and method
Carlson, Larry W.
1986-01-01
A fuel injection system and method provide for shaping a combustion plume within a combustion chamber to effectively recirculate hot combustion gases for stable combustion conditions while providing symmetrical combustion conditions. Char and molten slag are passed to the outer boundary layer to complete combustion of char while permitting initial substoichiometric combustion in a reductive atmosphere for reducing discharge of nitrogen oxides. Shaping of the plume is accomplished by an axially adjustable pintle which permits apportionment of driving pressure between elements which contribute tangential and those which contribute radial directional components to oxidant flow entering the combustion chamber.
Process Improvement Through Tool Integration in Aero-Mechanical Design
NASA Technical Reports Server (NTRS)
Briggs, Clark
2010-01-01
Emerging capabilities in commercial design tools promise to significantly improve the multi-disciplinary and inter-disciplinary design and analysis coverage for aerospace mechanical engineers. This paper explores the analysis process for two example problems of a wing and flap mechanical drive system and an aircraft landing gear door panel. The examples begin with the design solid models and include various analysis disciplines such as structural stress and aerodynamic loads. Analytical methods include CFD, multi-body dynamics with flexible bodies and structural analysis. Elements of analysis data management, data visualization and collaboration are also included.
Fuel injection device and method
Carlson, Larry W.
1986-02-04
A fuel injection system and method provide for shaping a combustion plume within a combustion chamber to effectively recirculate hot combustion gases for stable combustion conditions while providing symmetrical combustion conditions. Char and molten slag are passed to the outer boundary layer to complete combustion of char while permitting initial substoichiometric combustion in a reductive atmosphere for reducing discharge of nitrogen oxides. Shaping of the plume is accomplished by an axially adjustable pintle which permits apportionment of driving pressure between elements which contribute tangential and those which contribute radial directional components to oxidant flow entering the combustion chamber.
NASA Astrophysics Data System (ADS)
Lucian, P.; Gheorghe, S.
2017-08-01
This paper presents a new method, based on FRISCO formula, for optimizing the choice of the best control system for kinematical feed chains with great distance between slides used in computer numerical controlled machine tools. Such machines are usually, but not limited to, used for machining large and complex parts (mostly in the aviation industry) or complex casting molds. For such machine tools the kinematic feed chains are arranged in a dual-parallel drive structure that allows the mobile element to be moved by the two kinematical branches and their related control systems. Such an arrangement allows for high speed and high rigidity (a critical requirement for precision machining) during the machining process. A significant issue for such an arrangement it’s the ability of the two parallel control systems to follow the same trajectory accurately in order to address this issue it is necessary to achieve synchronous motion control for the two kinematical branches ensuring that the correct perpendicular position it’s kept by the mobile element during its motion on the two slides.
Tumor heterogeneity and progression: conceptual foundations for modeling.
Greller, L D; Tobin, F L; Poste, G
1996-01-01
A conceptual foundation for modeling tumor progression, growth, and heterogeneity is presented. The purpose of such models is to aid understanding, test ideas, formulate experiments, and to model cancer 'in machina' to address the dynamic features of tumor cell heterogeneity, progression, and growth. The descriptive capabilities of such an approach provides a consistent language for qualitatively reasoning about tumor behavior. This approach provides a schema for building conceptual models that combine three key phenomenological driving elements: growth, progression, and genetic instability. The growth element encompasses processes contributing to changes in tumor bulk and is distinct from progression per se. The progression element subsumes a broad collection of processes underlying phenotypic progression. The genetics elements represents heritable changes which potentially affect tumor character and behavior. Models, conceptual and mathematical, can be built for different tumor situations by drawing upon the interaction of these three distinct driving elements. These models can be used as tools to explore a diversity of hypotheses concerning dynamic changes in cellular populations during tumor progression, including the generation of intratumor heterogeneity. Such models can also serve to guide experimentation and to gain insight into dynamic aspects of complex tumor behavior.
Williamson, Matthew M.; Pratt, Gill A.
1999-06-08
The invention provides an elastic actuator consisting of a motor and a motor drive transmission connected at an output of the motor. An elastic element is connected in series with the motor drive transmission, and this elastic element is positioned to alone support the full weight of any load connected at an output of the actuator. A single force transducer is positioned at a point between a mount for the motor and an output of the actuator. This force transducer generates a force signal, based on deflection of the elastic element, that indicates force applied by the elastic element to an output of the actuator. An active feedback force control loop is connected between the force transducer and the motor for controlling the motor. This motor control is based on the force signal to deflect the elastic element an amount that produces a desired actuator output force. The produced output force is substantially independent of load motion. The invention also provides a torsional spring consisting of a flexible structure having at least three flat sections each connected integrally with and extending radially from a central section. Each flat section extends axially along the central section from a distal end of the central section to a proximal end of the central section.
Conceptual design of a mobile remote manipulator system
NASA Technical Reports Server (NTRS)
Bush, H. G.; Mikulas, M. M., Jr.; Wallsom, R. E.; Jensen, J. K.
1984-01-01
A mobile remote manipulator system has been identified as a necessary device for space station. A conceptual design for an MRMS is presented which features (1) tracks on the MRMS and guide pins only on the truss structure, (2) a push/pull drive mechanism which rotates to permit movement in four directions, and (3) spacecrane and mobile foot restraint manipulators (or arms). Operational and design features of the MRMS elements are described and illustrated. Concepts are also presented which permit rotating the operational plane of the MRMS through 90 deg. Such a system has been found to have great utility for initial space station construction, maintenance and repair, and to provide a construction capability for future station growth or large spacecraft assembly and/or servicing.
Digital controller design: Analysis of the annular suspension pointing system
NASA Technical Reports Server (NTRS)
Kuo, B. C.
1979-01-01
The Annular Suspension and Pointing System (ASPS) is a payload auxiliary pointing device of the Space Shuttle. The ASPS is comprised of two major subassemblies, a vernier and a coarse pointing subsystem. The experiment is attached to a mounting plate/rim combination which is suspended on magnetic bearing/actuators (MBA) strategically located about the rim. Fine pointing is achieved by gimballing the plate/rim within the MBA gaps. Control about the experiment line-of-sight is obtained through the use of a non-contacting rim drive and positioning torquer. All sensors used to close the servo loops on the vernier system are noncontacting elements. Therefore, the experiment is a free-flyer constrained only by the magnetic forces generated by the control loops.
Nuclear reactor remote disconnect control rod coupling indicator
Vuckovich, Michael
1977-01-01
A coupling indicator for use with nuclear reactor control rod assemblies which have remotely disengageable couplings between the control rod and the control rod drive shaft. The coupling indicator indicates whether the control rod and the control rod drive shaft are engaged or disengaged. A resistive network, utilizing magnetic reed switches, senses the position of the control rod drive mechanism lead screw and the control rod position indicating tube, and the relative position of these two elements with respect to each other is compared to determine whether the coupling is engaged or disengaged.
Bevel gear driver and method having torque limit selection
NASA Technical Reports Server (NTRS)
Cook, Joseph S., Jr. (Inventor)
1994-01-01
This invention comprises a torque drive mechanism utilizing axially translatable, mutually engageable transmission members having mating crown gears, driven and driving members with a three-element drive train being biased together by resilient means or by a fluid actuator system, the apparatus being operable to transmit a precisely controlled degree of torque to a driven member. The apparatus is applicable for use in hand tools and as a replacement for impact torque drivers, torque wrenches, motorized screw drivers, or the like, wherein the applied torque must be precisely controlled or limited. The bevel torque drive includes a drive gear which is axially displaceable and rotatable within cylindrical driver housing, a rotatable intermediate gear, and an output gear. Key rotationally secures displaceable gear with respect to input shaft but permits axial movement therebetween. A thrust bearing is preferably connected to the lower end of shaft for support to reduce play and friction between shaft and a transmission joint disc during rotation of the gear train. Coaxially mounted coiled spring is footed against displaceable gear for biasing the displaceable gear toward and into engagement with the intermediate gear for driving intermediate gear and output gear. Torque control is achieved by the use of straight or spiral beveled gears which are of configurations adapted to withdraw from mutual engagement upon the torque exceeding a predetermined limit. The novel, advantageous features of the invention include the configuration of the mating, crown gear sets and the axially translatable, slidable drive gear. The mechanism is capable of transmitting a high degree of torque within a narrow, compact transmission housing. The compact size and narrow, elongated configuration of the housing is particularly applicable for use in hand tools and in multiple torque driver mechanisms in which it is necessary to drive multiple fasteners which are located in close proximity. Prior torque drivers such as 'click-type' torque wrenches do not actually limit torque application but only provide an audible warning that the limit has been reached.
An examination of the concept of driving point receptance
NASA Astrophysics Data System (ADS)
Sheng, X.; He, Y.; Zhong, T.
2018-04-01
In the field of vibration, driving point receptance is a well-established and widely applied concept. However, as demonstrated in this paper, when a driving point receptance is calculated using the finite element (FE) method with solid elements, it does not converge as the FE mesh becomes finer, suggesting that there is a singularity. Hence, the concept of driving point receptance deserves a rigorous examination. In this paper, it is firstly shown that, for a point harmonic force applied on the surface of an elastic half-space, the Boussinesq formula can be applied to calculate the displacement amplitude of the surface if the response point is sufficiently close to the load. Secondly, by applying the Betti reciprocal theorem, it is shown that the displacement of an elastic body near a point harmonic force can be decomposed into two parts, with the first one being the displacement of an elastic half-space. This decomposition is useful, since it provides a solid basis for the introduction of a contact spring between a wheel and a rail in interaction. However, according to the Boussinesq formula, this decomposition also leads to the conclusion that a driving point receptance is infinite (singular), and would be undefinable. Nevertheless, driving point receptances have been calculated using different methods. Since the singularity identified in this paper was not appreciated, no account was given to the singularity in these calculations. Thus, the validity of these calculation methods must be examined. This constructs the third part of the paper. As the final development of the paper, the above decomposition is utilised to define and determine driving point receptances required for dealing with wheel/rail interactions.
Driving a car with custom-designed fuzzy inferencing VLSI chips and boards
NASA Technical Reports Server (NTRS)
Pin, Francois G.; Watanabe, Yutaka
1993-01-01
Vehicle control in a-priori unknown, unpredictable, and dynamic environments requires many calculational and reasoning schemes to operate on the basis of very imprecise, incomplete, or unreliable data. For such systems, in which all the uncertainties can not be engineered away, approximate reasoning may provide an alternative to the complexity and computational requirements of conventional uncertainty analysis and propagation techniques. Two types of computer boards including custom-designed VLSI chips were developed to add a fuzzy inferencing capability to real-time control systems. All inferencing rules on a chip are processed in parallel, allowing execution of the entire rule base in about 30 microseconds, and therefore, making control of 'reflex-type' of motions envisionable. The use of these boards and the approach using superposition of elemental sensor-based behaviors for the development of qualitative reasoning schemes emulating human-like navigation in a-priori unknown environments are first discussed. Then how the human-like navigation scheme implemented on one of the qualitative inferencing boards was installed on a test-bed platform to investigate two control modes for driving a car in a-priori unknown environments on the basis of sparse and imprecise sensor data is described. In the first mode, the car navigates fully autonomously, while in the second mode, the system acts as a driver's aid providing the driver with linguistic (fuzzy) commands to turn left or right and speed up or slow down depending on the obstacles perceived by the sensors. Experiments with both modes of control are described in which the system uses only three acoustic range (sonar) sensor channels to perceive the environment. Simulation results as well as indoors and outdoors experiments are presented and discussed to illustrate the feasibility and robustness of autonomous navigation and/or safety enhancing driver's aid using the new fuzzy inferencing hardware system and some human-like reasoning schemes which may include as little as six elemental behaviors embodied in fourteen qualitative rules.
2012-01-01
Alcoholism can be defined by a compulsion to seek and take drug, loss of control in limiting intake, and the emergence of a negative emotional state when access to the drug is prevented. Alcoholism impacts multiple motivational mechanisms and can be conceptualized as a disorder that includes a progression from impulsivity (positive reinforcement) to compulsivity (negative reinforcement). The compulsive drug seeking associated with alcoholism can be derived from multiple neuroadaptations, but the thesis argued here is that a key component involves the construct of negative reinforcement. Negative reinforcement is defined as drug taking that alleviates a negative emotional state. The negative emotional state that drives such negative reinforcement is hypothesized to derive from dysregulation of specific neurochemical elements involved in reward and stress within the basal forebrain structures involving the ventral striatum and extended amygdala, respectively. Specific neurochemical elements in these structures include not only decreases in reward neurotransmission, such as decreased dopamine and γ-aminobutyric acid function in the ventral striatum, but also recruitment of brain stress systems, such as corticotropin-releasing factor (CRF), in the extended amygdala. Acute withdrawal from chronic alcohol, sufficient to produce dependence, increases reward thresholds, increases anxiety-like responses, decreases dopamine system function, and increases extracellular levels of CRF in the central nucleus of the amygdala. CRF receptor antagonists also block excessive drug intake produced by dependence. A brain stress response system is hypothesized to be activated by acute excessive drug intake, to be sensitized during repeated withdrawal, to persist into protracted abstinence, and to contribute to the compulsivity of alcoholism. Other components of brain stress systems in the extended amygdala that interact with CRF and that may contribute to the negative motivational state of withdrawal include norepinephrine, dynorphin, and neuropeptide Y. The combination of loss of reward function and recruitment of brain stress systems provides a powerful neurochemical basis for a negative emotional state that is responsible for the negative reinforcement driving, at least partially, the compulsivity of alcoholism. PMID:21744309
Dong, Ren G; Welcome, Daniel E; McDowell, Thomas W; Wu, John Z
2013-11-25
The relationship between the vibration transmissibility and driving-point response functions (DPRFs) of the human body is important for understanding vibration exposures of the system and for developing valid models. This study identified their theoretical relationship and demonstrated that the sum of the DPRFs can be expressed as a linear combination of the transmissibility functions of the individual mass elements distributed throughout the system. The relationship is verified using several human vibration models. This study also clarified the requirements for reliably quantifying transmissibility values used as references for calibrating the system models. As an example application, this study used the developed theory to perform a preliminary analysis of the method for calibrating models using both vibration transmissibility and DPRFs. The results of the analysis show that the combined method can theoretically result in a unique and valid solution of the model parameters, at least for linear systems. However, the validation of the method itself does not guarantee the validation of the calibrated model, because the validation of the calibration also depends on the model structure and the reliability and appropriate representation of the reference functions. The basic theory developed in this study is also applicable to the vibration analyses of other structures.
Guan, Jing; Wang, Wanying
2017-01-01
ABSTRACT CRISPR-Cas (clustered regularly interspaced short palindromic repeat [CRISPR]-CRISPR-associated protein [Cas]) systems can provide protection against invading genetic elements by using CRISPR RNAs (crRNAs) as a guide to locate and degrade the target DNA. CRISPR-Cas systems have been classified into two classes and five types according to the content of cas genes. Previous studies have indicated that CRISPR-Cas systems can avoid viral infection and block plasmid transfer. Here we show that chromosomal targeting by the Staphylococcus aureus type III-A CRISPR-Cas system can drive large-scale genome deletion and alteration within integrated staphylococcal cassette chromosome mec (SCCmec). The targeting activity of the CRISPR-Cas system is associated with the complementarity between crRNAs and protospacers, and 10- to 13-nucleotide truncations of spacers partially block CRISPR attack and more than 13-nucleotide truncation can fully abolish targeting, suggesting that a minimal length is required to license cleavage. Avoiding base pairings in the upstream region of protospacers is also necessary for CRISPR targeting. Successive trinucleotide complementarity between the 5′ tag of crRNAs and protospacers can disrupt targeting. Our findings reveal that type III-A CRISPR-Cas systems can modulate bacterial genome stability and may serve as a high-efficiency tool for deleting resistance or virulence genes in bacteria. IMPORTANCE Staphylococcus aureus is a pathogen that can cause a wide range of infections in humans. Studies have suggested that CRISPR-Cas systems can drive the loss of integrated mobile genetic elements (MGEs) by chromosomal targeting. Here we demonstrate that CRISPR-mediated cleavage contributes to the partial deletion of integrated SCCmec in methicillin-resistant S. aureus (MRSA), which provides a strategy for the treatment of MRSA infections. The spacer within artificial CRISPR arrays should contain more than 25 nucleotides for immunity, and consecutive trinucleotide pairings between a selected target and the 5′ tag of crRNA can block targeting. These findings add to our understanding of the molecular mechanisms of the type III-A CRISPR-Cas system and provide a novel strategy for the exploitation of engineered CRISPR immunity against integrated MGEs in bacteria for clinical and industrial applications. PMID:29152580
Guan, Jing; Wang, Wanying; Sun, Baolin
2017-01-01
CRISPR-Cas (clustered regularly interspaced short palindromic repeat [CRISPR]-CRISPR-associated protein [Cas]) systems can provide protection against invading genetic elements by using CRISPR RNAs (crRNAs) as a guide to locate and degrade the target DNA. CRISPR-Cas systems have been classified into two classes and five types according to the content of cas genes. Previous studies have indicated that CRISPR-Cas systems can avoid viral infection and block plasmid transfer. Here we show that chromosomal targeting by the Staphylococcus aureus type III-A CRISPR-Cas system can drive large-scale genome deletion and alteration within integrated staphylococcal cassette chromosome mec (SCC mec ). The targeting activity of the CRISPR-Cas system is associated with the complementarity between crRNAs and protospacers, and 10- to 13-nucleotide truncations of spacers partially block CRISPR attack and more than 13-nucleotide truncation can fully abolish targeting, suggesting that a minimal length is required to license cleavage. Avoiding base pairings in the upstream region of protospacers is also necessary for CRISPR targeting. Successive trinucleotide complementarity between the 5' tag of crRNAs and protospacers can disrupt targeting. Our findings reveal that type III-A CRISPR-Cas systems can modulate bacterial genome stability and may serve as a high-efficiency tool for deleting resistance or virulence genes in bacteria. IMPORTANCE Staphylococcus aureus is a pathogen that can cause a wide range of infections in humans. Studies have suggested that CRISPR-Cas systems can drive the loss of integrated mobile genetic elements (MGEs) by chromosomal targeting. Here we demonstrate that CRISPR-mediated cleavage contributes to the partial deletion of integrated SCC mec in methicillin-resistant S. aureus (MRSA), which provides a strategy for the treatment of MRSA infections. The spacer within artificial CRISPR arrays should contain more than 25 nucleotides for immunity, and consecutive trinucleotide pairings between a selected target and the 5' tag of crRNA can block targeting. These findings add to our understanding of the molecular mechanisms of the type III-A CRISPR-Cas system and provide a novel strategy for the exploitation of engineered CRISPR immunity against integrated MGEs in bacteria for clinical and industrial applications.
An advanced pitch change mechanism incorporating a hybrid traction drive
NASA Technical Reports Server (NTRS)
Steinetz, B. M.; Loewenthal, S. H.; Sargisson, D. F.; White, G.
1984-01-01
A design of a propeller pitch control mechanism is described that meets the demanding requirements of a high-power, advanced turboprop. In this application, blade twisting moment torque can be comparable to that of the main reduction gearbox output: precise pitch control, reliability and compactness are all at a premium. A key element in the design is a compact, high-ratio hybrid traction drive which offers low torque ripple and high torsional stiffness. The traction drive couples a high speed electric motor/alternator unit to a ball screw that actuates the blade control links. The technical merits of this arrangement and the performance characteristics of the traction drive are discussed.
Hawke, B.C.
1963-02-26
This patent relates to a releasable coupling connecting a control rod to a control rod drive. This remotely operable coupling mechanism can connect two elements which are laterally and angviarly misaligned, and provides a means for sensing the locked condition of the elements. The coupling utilizes a spherical bayonet joint which is locked against rotation by a ball detent lock. (AEC)
Stiers, Pieter-Jan; van Gastel, Nick; Moermans, Karen; Stockmans, Ingrid; Carmeliet, Geert
2017-12-01
To improve bone healing or regeneration more insight in the fate and role of the different skeletal cell types is required. Mouse models for fate mapping and lineage tracing of skeletal cells, using stage-specific promoters, have advanced our understanding of bone development, a process that is largely recapitulated during bone repair. However, validation of these models is often only performed during development, whereas proof of the activity and specificity of the used promoters during the bone regenerative process is limited. Here, we show that the regulatory elements of the 6kb collagen type II promoter are not adequate to drive gene expression during bone repair. Similarly, the 2.3kb promoter of collagen type I lacks activity in adult mice, but the 3.2kb promoter is suitable. Furthermore, Cre-mediated fate mapping allows the visualization of progeny, but this label retention may hinder to distinguish these cells from ones with active expression of the marker at later time points. Together, our results show that the lineage-specific regulatory elements driving gene expression during bone development differ from those required later in life and during bone repair, and justify validation of lineage-specific cell tracing and gene silencing strategies during fracture healing and bone regenerative applications. Copyright © 2017 Elsevier Inc. All rights reserved.
Balancing aggregation and smoothing errors in inverse models
Turner, A. J.; Jacob, D. J.
2015-06-30
Inverse models use observations of a system (observation vector) to quantify the variables driving that system (state vector) by statistical optimization. When the observation vector is large, such as with satellite data, selecting a suitable dimension for the state vector is a challenge. A state vector that is too large cannot be effectively constrained by the observations, leading to smoothing error. However, reducing the dimension of the state vector leads to aggregation error as prior relationships between state vector elements are imposed rather than optimized. Here we present a method for quantifying aggregation and smoothing errors as a function ofmore » state vector dimension, so that a suitable dimension can be selected by minimizing the combined error. Reducing the state vector within the aggregation error constraints can have the added advantage of enabling analytical solution to the inverse problem with full error characterization. We compare three methods for reducing the dimension of the state vector from its native resolution: (1) merging adjacent elements (grid coarsening), (2) clustering with principal component analysis (PCA), and (3) applying a Gaussian mixture model (GMM) with Gaussian pdfs as state vector elements on which the native-resolution state vector elements are projected using radial basis functions (RBFs). The GMM method leads to somewhat lower aggregation error than the other methods, but more importantly it retains resolution of major local features in the state vector while smoothing weak and broad features.« less
Balancing aggregation and smoothing errors in inverse models
NASA Astrophysics Data System (ADS)
Turner, A. J.; Jacob, D. J.
2015-01-01
Inverse models use observations of a system (observation vector) to quantify the variables driving that system (state vector) by statistical optimization. When the observation vector is large, such as with satellite data, selecting a suitable dimension for the state vector is a challenge. A state vector that is too large cannot be effectively constrained by the observations, leading to smoothing error. However, reducing the dimension of the state vector leads to aggregation error as prior relationships between state vector elements are imposed rather than optimized. Here we present a method for quantifying aggregation and smoothing errors as a function of state vector dimension, so that a suitable dimension can be selected by minimizing the combined error. Reducing the state vector within the aggregation error constraints can have the added advantage of enabling analytical solution to the inverse problem with full error characterization. We compare three methods for reducing the dimension of the state vector from its native resolution: (1) merging adjacent elements (grid coarsening), (2) clustering with principal component analysis (PCA), and (3) applying a Gaussian mixture model (GMM) with Gaussian pdfs as state vector elements on which the native-resolution state vector elements are projected using radial basis functions (RBFs). The GMM method leads to somewhat lower aggregation error than the other methods, but more importantly it retains resolution of major local features in the state vector while smoothing weak and broad features.
Balancing aggregation and smoothing errors in inverse models
NASA Astrophysics Data System (ADS)
Turner, A. J.; Jacob, D. J.
2015-06-01
Inverse models use observations of a system (observation vector) to quantify the variables driving that system (state vector) by statistical optimization. When the observation vector is large, such as with satellite data, selecting a suitable dimension for the state vector is a challenge. A state vector that is too large cannot be effectively constrained by the observations, leading to smoothing error. However, reducing the dimension of the state vector leads to aggregation error as prior relationships between state vector elements are imposed rather than optimized. Here we present a method for quantifying aggregation and smoothing errors as a function of state vector dimension, so that a suitable dimension can be selected by minimizing the combined error. Reducing the state vector within the aggregation error constraints can have the added advantage of enabling analytical solution to the inverse problem with full error characterization. We compare three methods for reducing the dimension of the state vector from its native resolution: (1) merging adjacent elements (grid coarsening), (2) clustering with principal component analysis (PCA), and (3) applying a Gaussian mixture model (GMM) with Gaussian pdfs as state vector elements on which the native-resolution state vector elements are projected using radial basis functions (RBFs). The GMM method leads to somewhat lower aggregation error than the other methods, but more importantly it retains resolution of major local features in the state vector while smoothing weak and broad features.
Kondo interactions from band reconstruction in YbInCu 4
Jarrige, I.; Kotani, A.; Yamaoka, H.; ...
2015-03-27
We combine resonant inelastic X-ray scattering (RIXS) and model calculations in the Kondo lattice compound YbInCu₄, a system characterized by a dramatic increase in Kondo temperature and associated valence fluctuations below a first-order valence transition at T≃42 K. In this study, the bulk-sensitive, element-specific, and valence-projected charge excitation spectra reveal an unusual quasi-gap in the Yb-derived state density which drives an instability of the electronic structure and renormalizes the low-energy effective Hamiltonian at the transition. Our results provide long-sought experimental evidence for a link between temperature-driven changes in the low-energy Kondo scale and the higher-energy electronic structure of this system.
Mode-locking in advection-reaction-diffusion systems: An invariant manifold perspective
NASA Astrophysics Data System (ADS)
Locke, Rory A.; Mahoney, John R.; Mitchell, Kevin A.
2018-01-01
Fronts propagating in two-dimensional advection-reaction-diffusion systems exhibit a rich topological structure. When the underlying fluid flow is periodic in space and time, the reaction front can lock to the driving frequency. We explain this mode-locking phenomenon using the so-called burning invariant manifolds (BIMs). In fact, the mode-locked profile is delineated by a BIM attached to a relative periodic orbit (RPO) of the front element dynamics. Changes in the type (and loss) of mode-locking can be understood in terms of local and global bifurcations of the RPOs and their BIMs. We illustrate these concepts numerically using a chain of alternating vortices in a channel geometry.
Universality of accelerating change
NASA Astrophysics Data System (ADS)
Eliazar, Iddo; Shlesinger, Michael F.
2018-03-01
On large time scales the progress of human technology follows an exponential growth trend that is termed accelerating change. The exponential growth trend is commonly considered to be the amalgamated effect of consecutive technology revolutions - where the progress carried in by each technology revolution follows an S-curve, and where the aging of each technology revolution drives humanity to push for the next technology revolution. Thus, as a collective, mankind is the 'intelligent designer' of accelerating change. In this paper we establish that the exponential growth trend - and only this trend - emerges universally, on large time scales, from systems that combine together two elements: randomness and amalgamation. Hence, the universal generation of accelerating change can be attained by systems with no 'intelligent designer'.
Giorgio, Ivan; Andreaus, Ugo; Scerrato, Daria; dell'Isola, Francesco
2016-10-01
In this paper, the phenomena of resorption and growth of bone tissue and resorption of the biomaterial inside a bicomponent system are studied by means of a numerical method based on finite elements. The material behavior is described by a poro-viscoelastic model with infiltrated voids. The mechanical stimulus that drives these processes is a linear combination of density of strain energy and viscous dissipation. The external excitation is represented by a bending load slowly variable with sinusoidal law characterized by different frequencies. Investigated aspects are the influence of the load frequency, of type of the stimulus and of the effective porosity on the time evolution of the mass densities of considered system.
Acoustic noise and pneumatic wave vortices energy harvesting on highways
NASA Astrophysics Data System (ADS)
Pogacian, S.; Bot, A.; Zotoiu, D.
2012-02-01
This paper is aimed to present the structure and the principle of a energy harvesting system that uses the air movement emanated from passing traffic to produce and accumulate electrical energy. Each of the system's elements consists of a inertial mass panel which oscillate when driving cars pass. The panel is attached to a linear electromagnetic mini generator (or/and some piezo electric micro generators) and at the time of passing, it produces energy which is store it in a supercapacitor or in a rechargeable battery. The concept can be applied to busy roads, and to high-frequented rail networks and it can work with street and road lighting, information panels and monitoring devices.
Isolation and characterization of a novel pollen-specific promoter in maize (Zea mays L.).
Wang, He; Fan, Mingxia; Wang, Guohong; Zhang, Chunyu; Shi, Lei; Wei, Zhengyi; Ma, Wenjuan; Chang, Jing; Huang, Senxin; Lin, Feng
2017-06-01
ZmSTK2_USP, located on the long arm of chromosome 4, belongs to the serine/threonine kinase gene in maize. The sequence analysis of 2100 bp upstream from the start codon ATG has shown that it contains cis-element motifs and two types of anther/pollen-specific promoter elements (GTGA and AGAAA), suggesting that it is the pollen-specific promoter. To investigate the function of ZmSTK2_USP promoter, the GUS gene fusion system was employed. In proZmSTK2_USP-GUS genetically modified plants, GUS activity was detected in mature pollen grains and pollen tubes but not found in other floral and vegetative tissues. These results show that proZmSTK2_USP is the pollen-specific promoter and drives pollen-specific activity during the middle stage of pollen development until pollen maturation.
Matsumura, Ritsuko; Akashi, Makoto
2017-09-29
Cell-autonomous oscillation in clock gene expression drives circadian rhythms. The development of comprehensive analytical techniques, such as bioinformatics and ChIP-sequencing, has enabled the genome-wide identification of potential circadian transcriptional elements that regulate the transcriptional oscillation of clock genes. However, detailed analyses using traditional biochemical and molecular-biological approaches, such as binding and reporter assays, are still necessary to determine whether these potential circadian transcriptional elements are actually functional and how significantly they contribute to driving transcriptional oscillation. Here, we focused on the molecular mechanism of transcriptional oscillations in the mammalian clock gene Period3 ( Per3 ). The PER3 protein is essential for robust peripheral clocks and is a key component in circadian output processes. We found three E box-like elements located upstream of human Per3 transcription start sites that additively contributed to cell-autonomous transcriptional oscillation. However, we also found that Per3 is still expressed in a circadian manner when all three E box-like elements are functionally impaired. We noted that Per3 transcription was activated by the synergistic actions of two D box-like elements and the three E box-like elements, leading to a drastic increase in circadian amplitude. Interestingly, circadian expression of Per3 was completely disrupted only when all five transcriptional elements were functionally impaired. These results indicate that three E box-like and two D box-like elements cooperatively and redundantly regulate cell-autonomous transcriptional oscillation of Per3 . © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.
High performance advanced tokamak regimes in DIII-D for next-step experiments
NASA Astrophysics Data System (ADS)
Greenfield, C. M.; Murakami, M.; Ferron, J. R.; Wade, M. R.; Luce, T. C.; Petty, C. C.; Menard, J. E.; Petrie, T. W.; Allen, S. L.; Burrell, K. H.; Casper, T. A.; DeBoo, J. C.; Doyle, E. J.; Garofalo, A. M.; Gorelov, I. A.; Groebner, R. J.; Hobirk, J.; Hyatt, A. W.; Jayakumar, R. J.; Kessel, C. E.; La Haye, R. J.; Jackson, G. L.; Lohr, J.; Makowski, M. A.; Pinsker, R. I.; Politzer, P. A.; Prater, R.; Strait, E. J.; Taylor, T. S.; West, W. P.; DIII-D Team
2004-05-01
Advanced Tokamak (AT) research in DIII-D [K. H. Burrell for the DIII-D Team, in Proceedings of the 19th Fusion Energy Conference, Lyon, France, 2002 (International Atomic Energy Agency, Vienna, 2002) published on CD-ROM] seeks to provide a scientific basis for steady-state high performance operation in future devices. These regimes require high toroidal beta to maximize fusion output and poloidal beta to maximize the self-driven bootstrap current. Achieving these conditions requires integrated, simultaneous control of the current and pressure profiles, and active magnetohydrodynamic stability control. The building blocks for AT operation are in hand. Resistive wall mode stabilization via plasma rotation and active feedback with nonaxisymmetric coils allows routine operation above the no-wall beta limit. Neoclassical tearing modes are stabilized by active feedback control of localized electron cyclotron current drive (ECCD). Plasma shaping and profile control provide further improvements. Under these conditions, bootstrap supplies most of the current. Steady-state operation requires replacing the remaining Ohmic current, mostly located near the half radius, with noninductive external sources. In DIII-D this current is provided by ECCD, and nearly stationary AT discharges have been sustained with little remaining Ohmic current. Fast wave current drive is being developed to control the central magnetic shear. Density control, with divertor cryopumps, of AT discharges with edge localized moding H-mode edges facilitates high current drive efficiency at reactor relevant collisionalities. A sophisticated plasma control system allows integrated control of these elements. Close coupling between modeling and experiment is key to understanding the separate elements, their complex nonlinear interactions, and their integration into self-consistent high performance scenarios. Progress on this development, and its implications for next-step devices, will be illustrated by results of recent experiment and simulation efforts.
2012-01-01
The theory of speciation is dominated by adaptationist thinking, with less attention to mechanisms that do not affect species adaptation. Degeneracy – the imperfect specificity of interactions between diverse elements of biological systems and their environments – is key to the adaptability of populations. A mathematical model was explored in which population and resource were distributed one-dimensionally according to trait value. Resource consumption was degenerate – neither strictly location-specific nor location-independent. As a result, the competition for resources among the elements of the population was non-local. Two modeling approaches, a modified differential-integral Verhulstian equation and a cellular automata model, showed similar results: narrower degeneracy led to divergent dynamics with suppression of intermediate forms, whereas broader degeneracy led to suppression of diversifying forms, resulting in population stasis with increasing phenotypic homogeneity. Such behaviors did not increase overall adaptation because they continued after the model populations achieved maximal resource consumption rates, suggesting that degeneracy-driven distributed competition for resources rather than selective pressure toward more efficient resource exploitation was the driving force. The solutions were stable in the presence of limited environmental stochastic variability or heritable phenotypic variability. A conclusion was made that both dynamic diversification and static homogeneity of populations may be outcomes of the same process – distributed competition for resource not affecting the overall adaptation – with the difference between them defined by the spread of trait degeneracy in a given environment. Thus, biological degeneracy is a driving force of both speciation and stasis in biology, which, by themselves, are not necessarily adaptive in nature. PMID:23268831
What limits the achievable areal densities of large aperture space telescopes?
NASA Astrophysics Data System (ADS)
Peterson, Lee D.; Hinkle, Jason D.
2005-08-01
This paper examines requirements trades involving areal density for large space telescope mirrors. A segmented mirror architecture is used to define a quantitative example that leads to relevant insight about the trades. In this architecture, the mirror consists of segments of non-structural optical elements held in place by a structural truss that rests behind the segments. An analysis is presented of the driving design requirements for typical on-orbit loads and ground-test loads. It is shown that the driving on-orbit load would be the resonance of the lowest mode of the mirror by a reaction wheel static unbalance. The driving ground-test load would be dynamics due to ground-induced random vibration. Two general conclusions are derived from these results. First, the areal density that can be allocated to the segments depends on the depth allocated to the structure. More depth in the structure allows the allocation of more mass to the segments. This, however, leads to large structural depth that might be a significant development challenge. Second, the requirement for ground-test-ability results in an order of magnitude or more depth in the structure than is required by the on-orbit loads. This leads to the proposition that avoiding ground test as a driving requirement should be a fundamental technology on par with the provision of deployable depth. Both are important structural challenges for these future systems.
A tip/tilt mirror with large dynamic range for the ESO VLT Four Laser Guide Star Facility
NASA Astrophysics Data System (ADS)
Rijnveld, N.; Henselmans, R.; Nijland, B.
2011-09-01
One of the critical elements in the Four Laser Guide Star Facility (4LGSF) for the ESO Very Large Telescope (VLT) is the Optical Tube Assembly (OTA), consisting of a stable 20x laser beam expander and an active tip/tilt mirror, the Field Selector Mechanism (FSM). This paper describes the design and performance testing of the FSM. The driving requirement for the FSM is its large stroke of +/-6.1 mrad, in combination with less than 1.5 μrad RMS absolute accuracy. The FSM design consists of a Zerodur mirror, bonded to a membrane spring and strut combination to allow only tip and tilt. Two spindle drives actuate the mirror, using a stiffness based transmission to increase resolution. Absolute accuracy is achieved with two differential inductive sensor pairs. A prototype of the FSM is realized to optimize the control configuration and measure its performance. Friction in the spindle drive is overcome by creating a local velocity control loop between the spindle drives and the shaft encoders. Accuracy is achieved by using a cascaded low bandwidth control loop with feedback from the inductive sensors. The pointing jitter and settling time of the FSM are measured with an autocollimator. The system performance meets the strict requirements, and is ready to be implemented in the first OTA.
Pixelized Device Control Actuators for Large Adaptive Optics
NASA Technical Reports Server (NTRS)
Knowles, Gareth J.; Bird, Ross W.; Shea, Brian; Chen, Peter
2009-01-01
A fully integrated, compact, adaptive space optic mirror assembly has been developed, incorporating new advances in ultralight, high-performance composite mirrors. The composite mirrors use Q-switch matrix architecture-based pixelized control (PMN-PT) actuators, which achieve high-performance, large adaptive optic capability, while reducing the weight of present adaptive optic systems. The self-contained, fully assembled, 11x11x4-in. (approx.= 28x28x10-cm) unit integrates a very-high-performance 8-in. (approx.=20-cm) optic, and has 8-kHz true bandwidth. The assembled unit weighs less than 15 pounds (=6.8 kg), including all mechanical assemblies, power electronics, control electronics, drive electronics, face sheet, wiring, and cabling. It requires just three wires to be attached (power, ground, and signal) for full-function systems integration, and uses a steel-frame and epoxied electronics. The three main innovations are: 1. Ultralightweight composite optics: A new replication method for fabrication of very thin composite 20-cm-diameter laminate face sheets with good as-fabricated optical figure was developed. The approach is a new mandrel resin surface deposition onto previously fabricated thin composite laminates. 2. Matrix (regenerative) power topology: Waveform correction can be achieved across an entire face sheet at 6 kHz, even for large actuator counts. In practice, it was found to be better to develop a quadrant drive, that is, four quadrants of 169 actuators behind the face sheet. Each quadrant has a single, small, regenerative power supply driving all 169 actuators at 8 kHz in effective parallel. 3. Q-switch drive architecture: The Q-switch innovation is at the heart of the matrix architecture, and allows for a very fast current draw into a desired actuator element in 120 counts of a MHz clock without any actuator coupling.
Yunta, Jorge; Garcia-Pozuelo, Daniel; Diaz, Vicente; Olatunbosun, Oluremi
2018-02-06
Tires are a key sub-system of vehicles that have a big responsibility for comfort, fuel consumption and traffic safety. However, current tires are just passive rubber elements which do not contribute actively to improve the driving experience or vehicle safety. The lack of information from the tire during driving gives cause for developing an intelligent tire. Therefore, the aim of the intelligent tire is to monitor tire working conditions in real-time, providing useful information to other systems and becoming an active system. In this paper, tire tread deformation is measured to provide a strong experimental base with different experiments and test results by means of a tire fitted with sensors. Tests under different working conditions such as vertical load or slip angle have been carried out with an indoor tire test rig. The experimental data analysis shows the strong relation that exists between lateral force and the maximum tensile and compressive strain peaks when the tire is not working at the limit of grip. In the last section, an estimation system from experimental data has been developed and implemented in Simulink to show the potential of strain sensors for developing intelligent tire systems, obtaining as major results a signal to detect tire's loss of grip and estimations of the lateral friction coefficient.
Matrix light and pixel light: optical system architecture and requirements to the light source
NASA Astrophysics Data System (ADS)
Spinger, Benno; Timinger, Andreas L.
2015-09-01
Modern Automotive headlamps enable improved functionality for more driving comfort and safety. Matrix or Pixel light headlamps are not restricted to either pure low beam functionality or pure high beam. Light in direction of oncoming traffic is selectively switched of, potential hazard can be marked via an isolated beam and the illumination on the road can even follow a bend. The optical architectures that enable these advanced functionalities are diverse. Electromechanical shutters and lens units moved by electric motors were the first ways to realize these systems. Switching multiple LED light sources is a more elegant and mechanically robust solution. While many basic functionalities can already be realized with a limited number of LEDs, an increasing number of pixels will lead to more driving comfort and better visibility. The required optical system needs not only to generate a desired beam distribution with a high angular dynamic, but also needs to guarantee minimal stray light and cross talk between the different pixels. The direct projection of the LED array via a lens is a simple but not very efficient optical system. We discuss different optical elements for pre-collimating the light with minimal cross talk and improved contrast between neighboring pixels. Depending on the selected optical system, we derive the basic light source requirements: luminance, surface area, contrast, flux and color homogeneity.
Garcia-Pozuelo, Daniel; Diaz, Vicente; Olatunbosun, Oluremi
2018-01-01
Tires are a key sub-system of vehicles that have a big responsibility for comfort, fuel consumption and traffic safety. However, current tires are just passive rubber elements which do not contribute actively to improve the driving experience or vehicle safety. The lack of information from the tire during driving gives cause for developing an intelligent tire. Therefore, the aim of the intelligent tire is to monitor tire working conditions in real-time, providing useful information to other systems and becoming an active system. In this paper, tire tread deformation is measured to provide a strong experimental base with different experiments and test results by means of a tire fitted with sensors. Tests under different working conditions such as vertical load or slip angle have been carried out with an indoor tire test rig. The experimental data analysis shows the strong relation that exists between lateral force and the maximum tensile and compressive strain peaks when the tire is not working at the limit of grip. In the last section, an estimation system from experimental data has been developed and implemented in Simulink to show the potential of strain sensors for developing intelligent tire systems, obtaining as major results a signal to detect tire’s loss of grip and estimations of the lateral friction coefficient. PMID:29415513
Miniature electrically tunable rotary dual-focus lenses
NASA Astrophysics Data System (ADS)
Zou, Yongchao; Zhang, Wei; Lin, Tong; Chau, Fook Siong; Zhou, Guangya
2016-03-01
The emerging dual-focus lenses are drawing increasing attention recently due to their wide applications in both academia and industries, including laser cutting systems, microscopy systems, and interferometer-based surface profilers. In this paper, a miniature electrically tunable rotary dual-focus lens is developed. Such a lens consists of two optical elements, each having an optical flat surface and one freeform surface. The two freeform surfaces are initialized with the governing equation Ar2θ (A is the constant to be determined, r and θ denote the radii and angles in the polar coordinate system) and then optimized by ray tracing technique with additional Zernike polynomial terms for aberration correction. The freeform surfaces are achieved by a single-point diamond turning technique and then a PDMS-based replication process is utilized to materialize the final lens elements. To drive the two coaxial elements to rotate independently, two MEMS thermal rotary actuators are developed and fabricated by a standard MUMPs process. The experimental results show that the MEMS thermal actuator provides a maximum rotation angle of about 8.2 degrees with an input DC voltage of 6.5 V, leading to a wide tuning range for both the two focal lengths of the lens. Specifically, one focal length can be tuned from about 30 mm to 20 mm while the other one can be adjusted from about 30 mm to 60 mm.
NASA Technical Reports Server (NTRS)
DeMott, Diana; Fuqua, Bryan; Wilson, Paul
2013-01-01
Once a project obtains approval, decision makers have to consider a variety of alternative paths for completing the project and meeting the project objectives. How decisions are made involves a variety of elements including: cost, experience, current technology, ideologies, politics, future needs and desires, capabilities, manpower, timing, available information, and for many ventures management needs to assess the elements of risk versus reward. The use of high level Probabilistic Risk Assessment (PRA) Models during conceptual design phases provides management with additional information during the decision making process regarding the risk potential for proposed operations and design prototypes. The methodology can be used as a tool to: 1) allow trade studies to compare alternatives based on risk, 2) determine which elements (equipment, process or operational parameters) drives the risk, and 3) provide information to mitigate or eliminate risks early in the conceptual design to lower costs. Creating system models using conceptual design proposals and generic key systems based on what is known today can provide an understanding of the magnitudes of proposed systems and operational risks and facilitates trade study comparisons early in the decision making process. Identifying the "best" way to achieve the desired results is difficult, and generally occurs based on limited information. PRA provides a tool for decision makers to explore how some decisions will affect risk before the project is committed to that path, which can ultimately save time and money.
Automatic weld torch guidance control system
NASA Technical Reports Server (NTRS)
Smaith, H. E.; Wall, W. A.; Burns, M. R., Jr.
1982-01-01
A highly reliable, fully digital, closed circuit television optical, type automatic weld seam tracking control system was developed. This automatic tracking equipment is used to reduce weld tooling costs and increase overall automatic welding reliability. The system utilizes a charge injection device digital camera which as 60,512 inidividual pixels as the light sensing elements. Through conventional scanning means, each pixel in the focal plane is sequentially scanned, the light level signal digitized, and an 8-bit word transmitted to scratch pad memory. From memory, the microprocessor performs an analysis of the digital signal and computes the tracking error. Lastly, the corrective signal is transmitted to a cross seam actuator digital drive motor controller to complete the closed loop, feedback, tracking system. This weld seam tracking control system is capable of a tracking accuracy of + or - 0.2 mm, or better. As configured, the system is applicable to square butt, V-groove, and lap joint weldments.
Assessing drivers' response during automated driver support system failures with non-driving tasks.
Shen, Sijun; Neyens, David M
2017-06-01
With the increase in automated driver support systems, drivers are shifting from operating their vehicles to supervising their automation. As a result, it is important to understand how drivers interact with these automated systems and evaluate their effect on driver responses to safety critical events. This study aimed to identify how drivers responded when experiencing a safety critical event in automated vehicles while also engaged in non-driving tasks. In total 48 participants were included in this driving simulator study with two levels of automated driving: (a) driving with no automation and (b) driving with adaptive cruise control (ACC) and lane keeping (LK) systems engaged; and also two levels of a non-driving task (a) watching a movie or (b) no non-driving task. In addition to driving performance measures, non-driving task performance and the mean glance duration for the non-driving task were compared between the two levels of automated driving. Drivers using the automated systems responded worse than those manually driving in terms of reaction time, lane departure duration, and maximum steering wheel angle to an induced lane departure event. These results also found that non-driving tasks further impaired driver responses to a safety critical event in the automated system condition. In the automated driving condition, driver responses to the safety critical events were slower, especially when engaged in a non-driving task. Traditional driver performance variables may not necessarily effectively and accurately evaluate driver responses to events when supervising autonomous vehicle systems. Thus, it is important to develop and use appropriate variables to quantify drivers' performance under these conditions. Copyright © 2017 Elsevier Ltd and National Safety Council. All rights reserved.
Blow molding electric drives of Mechanical Engineering
NASA Astrophysics Data System (ADS)
Bukhanov, S. S.; Ramazanov, M. A.; Tsirkunenko, A. T.
2018-03-01
The article considers the questions about the analysis of new possibilities, which gives the use of adjustable electric drives for blowing mechanisms of plastic production. Thus, the use of new semiconductor converters makes it possible not only to compensate the instability of the supply network by using special dynamic voltage regulators, but to improve (correct) the power factor. The calculation of economic efficiency in controlled electric drives of blowing mechanisms is given. On the basis of statistical analysis, the calculation of the reliability parameters of the regulated electric drives’ elements under consideration is given. It is shown that an increase in the reliability of adjustable electric drives is possible both due to overestimation of the electric drive’s installed power, and in simpler schemes with pulse-vector control.
An advanced pitch change mechanism incorporating a hybrid traction drive
NASA Technical Reports Server (NTRS)
Steinetz, B. M.; Sargisson, D. F.; White, G.; Loewenthal, S. H.
1984-01-01
A design of a propeller pitch control mechanism is described that meets the demanding requirements of a high-power, advanced turboprop. In this application, blade twisting moment torque can be comparable to that of the main reduction gearbox output: precise pitch control, reliability and compactness are all at a premium. A key element in the design is a compact, high-ratio hybrid traction drive which offers low torque ripple and high torsional stiffness. The traction drive couples a high speed electric motor/alternator unit to a ball screw that actuates the blade control links. The technical merits of this arrangement and the performance characteristics of the traction drive are discussed. Comparisons are made to the more conventional pitch control mechanisms.
Cycling of oxyanion-forming trace elements in groundwaters from a freshwater deltaic marsh
NASA Astrophysics Data System (ADS)
Telfeyan, Katherine; Breaux, Alexander; Kim, Jihyuk; Kolker, Alexander S.; Cable, Jaye E.; Johannesson, Karen H.
2018-05-01
Pore waters and surface waters were collected from a freshwater system in southeastern Louisiana to investigate the geochemical cycling of oxyanion-forming trace elements (i.e., Mo, W, As, V). A small bayou (Bayou Fortier) receives input from a connecting lake (Lac des Allemands) and groundwater input at the head approximately 5 km directly south of the Mississippi River. Marsh groundwaters exchange with bayou surface water but are otherwise relatively isolated from outside hydrologic forcings, such as tides, storms, and effects from local navigation canals. Rather, redox processes in the marsh groundwaters appear to drive changes in trace element concentrations. Elevated dissolved S(-II) concentrations in marsh groundwaters suggest greater reducing conditions in the late fall and winter as compared to the spring and late summer. The data suggest that reducing conditions in marsh groundwaters initiate the dissolution of Fe(III)/Mn(IV) oxide/hydroxide minerals, which releases adsorbed and/or co-precipitated trace elements into solution. Once in solution, the fate of these elements is determined by complexation with aqueous species and precipitation with iron sulfide minerals. The trace elements remain soluble in the presence of Fe(III)- and SO42-- reducing conditions, suggesting that either kinetic limitations or complexation with aqueous ligands obfuscates the correlation between V and Mo sequestration in sediments with reducing or euxinic conditions.
The DIII-D Plasma Control System as a Scientific Research Tool
NASA Astrophysics Data System (ADS)
Hyatt, A. W.; Ferron, J. R.; Humphreys, D. A.; Leuer, J. A.; Walker, M. L.; Welander, A. S.
2006-10-01
The digital plasma control system (PCS) is an essential element of the DIII-D tokamak as a scientific research instrument, providing experimenters with real-time measurement and control of the plasma equilibrium, heating, current drive, transport, stability, and plasma-wall interactions. A wide range of sensors and actuators allow feedback control not only of global quantities such as discharge shape, plasma energy, and toroidal rotation, but also of non-axisymmetric magnetic fields and features of the internal profiles of temperature and current density. These diverse capabilities of the PCS improve the effectiveness of tokamak operation and enable unique physics experiments. We will present an overview of the PCS and the systems it controls and interacts with, and show examples of various plasma parameters controlled by the PCS and its actuators.
Williamson, M.M.; Pratt, G.A.
1999-06-08
The invention provides an elastic actuator consisting of a motor and a motor drive transmission connected at an output of the motor. An elastic element is connected in series with the motor drive transmission, and this elastic element is positioned to alone support the full weight of any load connected at an output of the actuator. A single force transducer is positioned at a point between a mount for the motor and an output of the actuator. This force transducer generates a force signal, based on deflection of the elastic element, that indicates force applied by the elastic element to an output of the actuator. An active feedback force control loop is connected between the force transducer and the motor for controlling the motor. This motor control is based on the force signal to deflect the elastic element an amount that produces a desired actuator output force. The produced output force is substantially independent of load motion. The invention also provides a torsional spring consisting of a flexible structure having at least three flat sections each connected integrally with and extending radially from a central section. Each flat section extends axially along the central section from a distal end of the central section to a proximal end of the central section. 30 figs.
Elastic actuator for precise force control
Pratt, G.A.; Williamson, M.M.
1997-07-22
The invention provides an elastic actuator consisting of a motor and a motor drive transmission connected at an output of the motor. An elastic element is connected in series with the motor drive transmission, and this elastic element is positioned to alone support the full weight of any load connected at an output of the actuator. A single force transducer is positioned at a point between a mount for the motor and an output of the actuator. This force transducer generates a force signal, based on deflection of the elastic element, that indicates force applied by the elastic element to an output of the actuator. An active feedback force control loop is connected between the force transducer and the motor for controlling the motor. This motor control is based on the force signal to deflect the elastic element an amount that produces a desired actuator output force. The produced output force is substantially independent of load motion. The invention also provides a torsional spring consisting of a flexible structure having at least three flat sections each connected integrally with and extending radially from a central section. Each flat section extends axially along the central section from a distal end of the central section to a proximal end of the central section. 30 figs.
Elastic actuator for precise force control
Pratt, Gill A.; Williamson, Matthew M.
1997-07-22
The invention provides an elastic actuator consisting of a motor and a motor drive transmission connected at an output of the motor. An elastic element is connected in series with the motor drive transmission, and this elastic element is positioned to alone support the full weight of any load connected at an output of the actuator. A single force transducer is positioned at a point between a mount for the motor and an output of the actuator. This force transducer generates a force signal, based on deflection of the elastic element, that indicates force applied by the elastic element to an output of the actuator. An active feedback force control loop is connected between the force transducer and the motor for controlling the motor. This motor control is based on the force signal to deflect the elastic element an amount that produces a desired actuator output force. The produced output force is substantially independent of load motion. The invention also provides a torsional spring consisting of a flexible structure having at least three flat sections each connected integrally with and extending radially from a central section. Each flat section extends axially along the central section from a distal end of the central section to a proximal end of the central section.
NASA'S Water Resources Element Within the Applied Sciences Program
NASA Technical Reports Server (NTRS)
Toll, David; Doorn, Bradley; Engman, Edwin
2011-01-01
The NASA Earth Systems Division has the primary responsibility for the Applied Science Program and the objective to accelerate the use of NASA science results in applications to help solve problems important to society and the economy. The primary goal of the NASA Applied Science Program is to improve future and current operational systems by infusing them with scientific knowledge of the Earth system gained through space-based observation, assimilation of new observations, and development and deployment of enabling technologies, systems, and capabilities. This paper discusses major problems facing water resources managers, including having timely and accurate data to drive their decision support tools. It then describes how NASA's science and space based satellites may be used to overcome this problem. Opportunities for the water resources community to participate in NASA's Water Resources Applications Program are described.
Using CRISPR-Cas systems as antimicrobials.
Bikard, David; Barrangou, Rodolphe
2017-06-01
Although CRISPR-Cas systems naturally evolved to provide adaptive immunity in bacteria and archaea, Cas nucleases can be co-opted to target chromosomal sequences rather than invasive genetic elements. Although genome editing is the primary outcome of self-targeting using CRISPR-based technologies in eukaryotes, self-targeting by CRISPR is typically lethal in bacteria. Here, we discuss how DNA damage introduced by Cas nucleases in bacteria can efficiently and specifically lead to plasmid curing or drive cell death. Specifically, we discuss how various CRISPR-Cas systems can be engineered and delivered using phages or phagemids as vectors. These principles establish CRISPR-Cas systems as potent and programmable antimicrobials, and open new avenues for the development of CRISPR-based tools for selective removal of bacterial pathogens and precise microbiome composition alteration. Copyright © 2017 Elsevier Ltd. All rights reserved.
Uranium mineralization in fluorine-enriched volcanic rocks
DOE Office of Scientific and Technical Information (OSTI.GOV)
Burt, D.M.; Sheridan, M.F.; Bikun, J.
1980-09-01
Several uranium and other lithophile element deposits are located within or adjacent to small middle to late Cenozoic, fluorine-rich rhyolitic dome complexes. Examples studied include Spor Mountain, Utah (Be-U-F), the Honeycomb Hills, Utah (Be-U), the Wah Wah Mountains, Utah (U-F), and the Black Range-Sierra Cuchillo, New Mexico (Sn-Be-W-F). The formation of these and similar deposits begins with the emplacement of a rhyolitic magma, enriched in lithophile metals and complexing fluorine, that rises to a shallow crustal level, where its roof zone may become further enriched in volatiles and the ore elements. During initial explosive volcanic activity, aprons of lithicrich tuffsmore » are erupted around the vents. These early pyroclastic deposits commonly host the mineralization, due to their initial enrichment in the lithophile elements, their permeability, and the reactivity of their foreign lithic inclusions (particularly carbonate rocks). The pyroclastics are capped and preserved by thick topaz rhyolite domes and flows that can serve as a source of heat and of additional quantities of ore elements. Devitrification, vapor-phase crystallization, or fumarolic alteration may free the ore elements from the glassy matrix and place them in a form readily leached by percolating meteoric waters. Heat from the rhyolitic sheets drives such waters through the system, generally into and up the vents and out through the early tuffs. Secondary alteration zones (K-feldspar, sericite, silica, clays, fluorite, carbonate, and zeolites) and economic mineral concentrations may form in response to this low temperature (less than 200 C) circulation. After cooling, meteoric water continues to migrate through the system, modifying the distribution and concentration of the ore elements (especially uranium).« less
Design and characterization of piezoelectric ultrasonic motors
NASA Astrophysics Data System (ADS)
Yener, Serra
This thesis presents modeling and prototype fabrication and characterization of new types of piezoelectric ultrasonic micromotors. Our approach in designing these piezoelectric motors was: (i) to simplify the structure including the poling configuration of piezoelectric elements used in the stator and (ii) to reduce the number of components in order to decrease the cost and enhance the driving reliability. There are two different types of piezoelectric motors designed throughout this research. The first of these designs consists of a metal tube, on which two piezoelectric ceramic plates poled in thickness direction, were bonded. Two orthogonal bending modes of the hollow cylinder were superimposed resulting in a rotational vibration. Since the structure and poling configuration of the active piezoelectric elements used in the stator are simple, this motor structure is very suitable for miniaturization. Moreover, a single driving source can excite two bending modes at the same time, thus generate a wobble motion. Three types of prototypes are included in this design. The piezoelectric stator structure is the same for all. However, the dimensions of the motors are reduced by almost 50 percent. Starting with a 10 mm long stator, we reached to 4 mm in the last prototype. The initial diameter was 2.4 mm, which was reduced to 1.6 mm. In the final design, the rotor part of the motor was changed resulting in the reduction in the number of components. In terms of driving circuit, a single driving source was enough to run the motors and a conventional switching power supply type resonant L-C circuit was used. A simple motor structure with a simple driving circuit were combined successfully and fabricated inexpensively. The second design is a shear type piezoelectric linear motor. The behavior of a single rectangular piezoelectric shear plate was analyzed and after optimizing the dimensions and the mode characteristics, a prototype was fabricated. The prototype consists of one layer of ceramic and a brass teeth-like layer bonded on it. The displacement was amplified with the metal layer, the teeth of which were placed on the points of in-phase motion. The targeted application area is paper-feeding mechanism. In terms of application areas for the first design, a gas valve system and a micro vehicle were constructed. In addition, a new optical coherence tomography endoscope by utilizing the piezoelectric micromotor was designed. Finally, the prototype motor was integrated inside the camera of a cell phone to drive the zoom mechanism.
A Vibrating Jaw Crusher with Auteresonant Electric Motor Drive of Swinging Movement
NASA Astrophysics Data System (ADS)
Zagrivniy, E. A.; Poddubniy, D. A.
2018-01-01
The article relates to a vibrating jaw crusher with pendulum vibrating exciter auteresonant electric motor drive and with elastic element rational force distribution, with limited peak-to-peak swing. Its design and its math model are presented. Also disclosed is the operating principle of a vibrating jaw crusher and the control algorithm for controlling the crushing jaw for maintaining the operating mode at resonant frequency.
Improving Motor and Drive System Performance – A Sourcebook for Industry
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
This sourcebook outlines opportunities to improve motor and drive systems performance. The sourcebook is divided into four main sections: (1) Motor and Drive System Basics: Summarizes important terms, relationships, and system design considerations relating to motor and drive systems. (2) Performance Opportunity Road Map: Details the key components of well-functioning motor and drive systems and opportunities for energy performance opportunities. (3) Motor System Economics: Offers recommendations on how to propose improvement projects based on corporate priorities, efficiency gains, and financial payback periods. (4) Where to Find Help: Provides a directory of organizations associated with motors and drives, as well asmore » resources for additional information, tools, software, videos, and training opportunities.« less
Centromere-associated meiotic drive and female fitness variation in Mimulus.
Fishman, Lila; Kelly, John K
2015-05-01
Female meiotic drive, in which chromosomal variants preferentially segregate to the egg pole during asymmetric female meiosis, is a theoretically pervasive but still mysterious form of selfish evolution. Like other selfish genetic elements, driving chromosomes may be maintained as balanced polymorphisms by pleiotropic or linked fitness costs. A centromere-associated driver (D) with a ∼58:42 female-specific transmission advantage occurs at intermediate frequency (32-40%) in the Iron Mountain population of the yellow monkeyflower, Mimulus guttatus. Previously determined male fertility costs are sufficient to prevent the fixation of D, but predict a higher equilibrium frequency. To better understand the dynamics and effects of D, we developed a new population genetic model and measured genotype-specific lifetime female fitness in the wild. In three of four years, and across all years, D imposed significant recessive seedset costs, most likely due to hitchhiking by deleterious mutations. With both male and female costs as measured, and 58:42 drive, our model predicts an equilibrium frequency of D (38%) very close to the observed value. Thus, D represents a rare selfish genetic element whose local population genetic dynamics have been fully parameterized, and the observation of equilibrium sets the stage for investigations of coevolution with suppressors. © 2015 The Author(s).
Generation of electrical power
Hursen, Thomas F.; Kolenik, Steven A.; Purdy, David L.
1976-01-01
A heat-to-electricity converter is disclosed which includes a radioactive heat source and a thermoelectric element of relatively short overall length capable of delivering a low voltage of the order of a few tenths of a volt. Such a thermoelectric element operates at a higher efficiency than longer higher-voltage elements; for example, elements producing 6 volts. In the generation of required power, thermoelectric element drives a solid-state converter which is controlled by input current rather than input voltage and operates efficiently for a high signal-plus-noise to signal ratio of current. The solid-state converter has the voltage gain necessary to deliver the required voltage at the low input of the thermoelectric element.
Integrated Vehicle Thermal Management for Advanced Vehicle Propulsion Technologies
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bennion, K.; Thornton, M.
A critical element to the success of new propulsion technologies that enable reductions in fuel use is the integration of component thermal management technologies within a viable vehicle package. Vehicle operation requires vehicle thermal management systems capable of balancing the needs of multiple vehicle systems that may require heat for operation, require cooling to reject heat, or require operation within specified temperature ranges. As vehicle propulsion transitions away from a single form of vehicle propulsion based solely on conventional internal combustion engines (ICEs) toward a wider array of choices including more electrically dominant systems such as plug-in hybrid electric vehiclesmore » (PHEVs), new challenges arise associated with vehicle thermal management. As the number of components that require active thermal management increase, so do the costs in terms of dollars, weight, and size. Integrated vehicle thermal management is one pathway to address the cost, weight, and size challenges. The integration of the power electronics and electric machine (PEEM) thermal management with other existing vehicle systems is one path for reducing the cost of electric drive systems. This work demonstrates techniques for evaluating and quantifying the integrated transient and continuous heat loads of combined systems incorporating electric drive systems that operate primarily under transient duty cycles, but the approach can be extended to include additional steady-state duty cycles typical for designing vehicle thermal management systems of conventional vehicles. The work compares opportunities to create an integrated low temperature coolant loop combining the power electronics and electric machine with the air conditioning system in contrast to a high temperature system integrated with the ICE cooling system.« less
NASA Technical Reports Server (NTRS)
Lipo, Thomas A.; Alan, Irfan
1991-01-01
Hard and soft switching test results conducted with one of the samples of first generation MOS-controlled thyristor (MCTs) and similar test results with several different samples of second generation MCT's are reported. A simple chopper circuit is used to investigate the basic switching characteristics of MCT under hard switching and various types of resonant circuits are used to determine soft switching characteristics of MCT under both zero voltage and zero current switching. Next, operation principles of a pulse density modulated converter (PDMC) for three phase (3F) to 3F two-step power conversion via parallel resonant high frequency (HF) AC link are reviewed. The details for the selection of power switches and other power components required for the construction of the power circuit for the second generation 3F to 3F converter system are discussed. The problems encountered in the first generation system are considered. Design and performance of the first generation 3F to 3F power converter system and field oriented induction moter drive based upon a 3 kVA, 20 kHz parallel resonant HF AC link are described. Low harmonic current at the input and output, unity power factor operation of input, and bidirectional flow capability of the system are shown via both computer and experimental results. The work completed on the construction and testing of the second generation converter and field oriented induction motor drive based upon specifications for a 10 hp squirrel cage dynamometer and a 20 kHz parallel resonant HF AC link is discussed. The induction machine is designed to deliver 10 hp or 7.46 kW when operated as an AC-dynamo with power fed back to the source through the converter. Results presented reveal that the proposed power level requires additional energy storage elements to overcome difficulties with a peak link voltage variation problem that limits reaching to the desired power level. The power level test of the second generation converter after the addition of extra energy storage elements to the HF link are described. The importance of the source voltage level to achieve a better current regulation for the source side PDMC is also briefly discussed. The power levels achieved in the motoring mode of operation show that the proposed power levels achieved in the generating mode of operation can also be easily achieved provided that no mechanical speed limitation were present to drive the induction machine at the proposed power level.
Lu, Benzhuo; Zhou, Y C; Huber, Gary A; Bond, Stephen D; Holst, Michael J; McCammon, J Andrew
2007-10-07
A computational framework is presented for the continuum modeling of cellular biomolecular diffusion influenced by electrostatic driving forces. This framework is developed from a combination of state-of-the-art numerical methods, geometric meshing, and computer visualization tools. In particular, a hybrid of (adaptive) finite element and boundary element methods is adopted to solve the Smoluchowski equation (SE), the Poisson equation (PE), and the Poisson-Nernst-Planck equation (PNPE) in order to describe electrodiffusion processes. The finite element method is used because of its flexibility in modeling irregular geometries and complex boundary conditions. The boundary element method is used due to the convenience of treating the singularities in the source charge distribution and its accurate solution to electrostatic problems on molecular boundaries. Nonsteady-state diffusion can be studied using this framework, with the electric field computed using the densities of charged small molecules and mobile ions in the solvent. A solution for mesh generation for biomolecular systems is supplied, which is an essential component for the finite element and boundary element computations. The uncoupled Smoluchowski equation and Poisson-Boltzmann equation are considered as special cases of the PNPE in the numerical algorithm, and therefore can be solved in this framework as well. Two types of computations are reported in the results: stationary PNPE and time-dependent SE or Nernst-Planck equations solutions. A biological application of the first type is the ionic density distribution around a fragment of DNA determined by the equilibrium PNPE. The stationary PNPE with nonzero flux is also studied for a simple model system, and leads to an observation that the interference on electrostatic field of the substrate charges strongly affects the reaction rate coefficient. The second is a time-dependent diffusion process: the consumption of the neurotransmitter acetylcholine by acetylcholinesterase, determined by the SE and a single uncoupled solution of the Poisson-Boltzmann equation. The electrostatic effects, counterion compensation, spatiotemporal distribution, and diffusion-controlled reaction kinetics are analyzed and different methods are compared.
Baedorf Kassis, Elias; Loring, Stephen H; Talmor, Daniel
2016-08-01
The driving pressure of the respiratory system has been shown to strongly correlate with mortality in a recent large retrospective ARDSnet study. Respiratory system driving pressure [plateau pressure-positive end-expiratory pressure (PEEP)] does not account for variable chest wall compliance. Esophageal manometry can be utilized to determine transpulmonary driving pressure. We have examined the relationships between respiratory system and transpulmonary driving pressure, pulmonary mechanics and 28-day mortality. Fifty-six patients from a previous study were analyzed to compare PEEP titration to maintain positive transpulmonary end-expiratory pressure to a control protocol. Respiratory system and transpulmonary driving pressures and pulmonary mechanics were examined at baseline, 5 min and 24 h. Analysis of variance and linear regression were used to compare 28 day survivors versus non-survivors and the intervention group versus the control group, respectively. At baseline and 5 min there was no difference in respiratory system or transpulmonary driving pressure. By 24 h, survivors had lower respiratory system and transpulmonary driving pressures. Similarly, by 24 h the intervention group had lower transpulmonary driving pressure. This decrease was explained by improved elastance and increased PEEP. The results suggest that utilizing PEEP titration to target positive transpulmonary pressure via esophageal manometry causes both improved elastance and driving pressures. Treatment strategies leading to decreased respiratory system and transpulmonary driving pressure at 24 h may be associated with improved 28 day mortality. Studies to clarify the role of respiratory system and transpulmonary driving pressures as a prognosticator and bedside ventilator target are warranted.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bahrdt, J.; Baecker, H.-J.; Frentrup, W.
Helmholtzzentrum Berlin has built an APPLE II undulator for the storage ring PETRA III. The device has a total length of 5m and a minimum gap of 11mm. The high magnetic forces in particular in the inclined mode have been analyzed by means of finite element methods (FEM). Specific mechanic components such as flexible joints have been optimized to cope with the gap- and shift-dependent 3D-forces and a sophisticated control and drive system has been implemented. After completion of the device, detailed laser interferometer measurements for all operation modes have been performed. The data are compared to the FEM simulations.
Research requirements for development of regenerative engines for helicopters
DOE Office of Scientific and Technical Information (OSTI.GOV)
Semple, R.D.
1976-12-01
The improved specific fuel consumption of the regenerative engine was compared to a simple-cycle turboshaft engine. The performance improvement and fuel saving are obtained at the expense of increased engine weight, development and production costs, and maintenance costs. Costs and schedules are estimated for the elements of the research and development program. Interaction of the regenerative engine with other technology goals for an advanced civil helicopter is examined, including its impact on engine noise, hover and cruise performance, helicopter empty weight, drive-system efficiency and weight, one-engine-inoperative hover capability, and maintenance and reliability.
Research requirements for development of regenerative engines for helicopters
NASA Technical Reports Server (NTRS)
Semple, R. D.
1976-01-01
The improved specific fuel consumption of the regenerative engine was compared to a simple-cycle turboshaft engine. The performance improvement and fuel saving are obtained at the expense of increased engine weight, development and production costs, and maintenance costs. Costs and schedules are estimated for the elements of the research and development program. Interaction of the regenerative engine with other technology goals for an advanced civil helicopter is examined, including its impact on engine noise, hover and cruise performance, helicopter empty weight, drive-system efficiency and weight, one-engine-inoperative hover capability, and maintenance and reliability.
Solar Radiometric Data Quality Assessment of SIRS, SKYRAD and GNDRAD Measurements (Poster)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Habte, A.; Stoffel, T.; Reda, I.
2014-03-01
Solar radiation is the driving force for the earth's weather and climate. Understanding the elements of this dynamic energy balance requires accurate measurements of broadband solar irradiance. Since the mid-1990's the ARM Program has deployed pyrheliometers and pyranometers for the measurement of direct normal irradiance (DNI), global horizontal irradiance (GHI), diffuse horizontal irradiance (DHI), and upwelling shortwave (US) radiation at permanent and mobile field research sites. This poster summarizes the basis for assessing the broadband solar radiation data available from the SIRS, SKYRAD, and GNDRAD measurement systems and provides examples of data inspections.
NASA Astrophysics Data System (ADS)
Huan, Huiting; Gao, Chunming; Liu, Lixian; Sun, Qiming; Zhao, Binxing; Yan, Laijun
2015-06-01
Transdermal drug delivery (TDD) implemented by especially low-frequency ultrasound is generally known as sonophoresis or phonophoresis which has drawn considerable wide attention. However, TDD has not yet achieved its full potential as an alternative to conventional drug delivery methods due to its bulky instruments. In this paper, a cymbal-type piezoelectric composite transducer (CPCT) which has advantages over a traditional ultrasound generator in weight, flexibility, and power consumption, is used as a substitute ultrasonicator to realize TDD. First, theoretical research on a CPCT based on the finite element analysis was carried out according to which a series of applicable CPCTs with bandwidths of 20 kHz to 100 kHz were elaborated. Second, a TDD experimental setup was built with previously fabricated CPCTs aimed at the administration of glucose. Finally, the TDD performance of glucose molecule transport in porcine skin was measured in vitro by quantifying the concentration of glucose, and the time variation curves were subsequently obtained. During the experiment, the driving wave form, frequency, and power consumption of the transducers were selected as the main elements which determined the efficacy of glucose delivery. The results indicate that the effectiveness of the CPCT-based delivery is constrained more by the frequency and intensity of ultrasound rather than the driving waveform. The light-weight, flexibility, and low-power consumption of a CPCT can potentially achieve effective TDD.
The Visual Representation and Acquisition of Driving Knowledge for Autonomous Vehicle
NASA Astrophysics Data System (ADS)
Zhang, Zhaoxia; Jiang, Qing; Li, Ping; Song, LiangTu; Wang, Rujing; Yu, Biao; Mei, Tao
2017-09-01
In this paper, the driving knowledge base of autonomous vehicle is designed. Based on the driving knowledge modeling system, the driving knowledge of autonomous vehicle is visually acquired, managed, stored, and maintenanced, which has vital significance for creating the development platform of intelligent decision-making systems of automatic driving expert systems for autonomous vehicle.
Rotor and bearing system for a turbomachine
Lubell, Daniel; Weissert, Dennis
2006-09-26
A rotor and bearing system for a turbomachine. The turbomachine includes a drive shaft, an impeller positioned on the drive shaft, and a turbine positioned on the drive shaft proximate to the impeller. The bearing system comprises one gas journal bearing supporting the drive shaft between the impeller and the turbine. The area between the impeller and the turbine is an area of increased heat along the drive shaft in comparison to other locations along the drive shaft. The section of the drive shaft positioned between impeller and the turbine is also a section of the drive shaft that experiences increased stressed and load in the turbomachine. The inventive bearing machine system positions only one radial bearing in this area of increased stress and load.
Beck-Krala, Ewa; Klimkiewicz, Katarzyna
2016-12-01
Occupational safety and health (OSH) plays a significant role in today's organizations, because it helps in attracting and retaining employees as well as molding their attitudes and behaviors at work. This is why the issue of OSH is stressed in a comprehensive approach to employee rewards: the total reward concept. This article explains how OSH may be included in a complex evaluation process of the compensation system. Although the literature on the effectiveness of employee compensation refers mainly to financial and non-financial components, there is a need for inclusion of working conditions in such analyses. An evaluation of the compensation system that incorporates OSH can drive many benefits for both the organization and employees. Obtaining such benefits, however, requires systematic evaluation of the reward system, including OSH. Incorporation of OSH issue within the comprehensive analysis of compensation systems promotes responsible behavior of all stakeholders.
Meeting the challenges of developing LED-based projection displays
NASA Astrophysics Data System (ADS)
Geißler, Enrico
2006-04-01
The main challenge in developing a LED-based projection system is to meet the brightness requirements of the market. Therefore a balanced combination of optical, electrical and thermal parameters must be reached to achieve these performance and cost targets. This paper describes the system design methodology for a digital micromirror display (DMD) based optical engine using LEDs as the light source, starting at the basic physical and geometrical parameters of the DMD and other optical elements through characterization of the LEDs to optimizing the system performance by determining optimal driving conditions. LEDs have a luminous flux density which is just at the threshold of acceptance in projection systems and thus only a fully optimized optical system with a matched set of LEDs can be used. This work resulted in two projection engines, one for a compact pocket projector and the other for a rear projection television, both of which are currently in commercialization.
LEDs on the threshold for use in projection systems: challenges, limitations and applications
NASA Astrophysics Data System (ADS)
Moffat, Bryce Anton
2006-02-01
The use of coloured LEDs as light sources in digital projectors depends on an optimal combination of optical, electrical and thermal parameters to meet the performance and cost targets needed to enable these products to compete in the marketplace. This paper describes the system design methodology for a digital micromirror display (DMD) based optical engine using LEDs as the light source, starting at the basic physical and geometrical parameters of the DMD and other optical elements through characterization of the LEDs to optimizing the system performance by determining optimal driving conditions. The main challenge in using LEDs is the luminous flux density, which is just at the threshold of acceptance in projection systems and thus only a fully optimized optical system with a uniformly bright set of LEDs can be used. As a result of this work we have developed two applications: a compact pocket projector and a rear projection television.
Ultrasonic Leak Detection System
NASA Technical Reports Server (NTRS)
Youngquist, Robert C. (Inventor); Moerk, J. Steven (Inventor)
1998-01-01
A system for detecting ultrasonic vibrations. such as those generated by a small leak in a pressurized container. vessel. pipe. or the like. comprises an ultrasonic transducer assembly and a processing circuit for converting transducer signals into an audio frequency range signal. The audio frequency range signal can be used to drive a pair of headphones worn by an operator. A diode rectifier based mixing circuit provides a simple, inexpensive way to mix the transducer signal with a square wave signal generated by an oscillator, and thereby generate the audio frequency signal. The sensitivity of the system is greatly increased through proper selection and matching of the system components. and the use of noise rejection filters and elements. In addition, a parabolic collecting horn is preferably employed which is mounted on the transducer assembly housing. The collecting horn increases sensitivity of the system by amplifying the received signals. and provides directionality which facilitates easier location of an ultrasonic vibration source.
Park, Dae-Heon; Park, Jang-Woo
2011-01-01
Dew condensation on the leaf surface of greenhouse crops can promote diseases caused by fungus and bacteria, affecting the growth of the crops. In this paper, we present a WSN (Wireless Sensor Network)-based automatic monitoring system to prevent dew condensation in a greenhouse environment. The system is composed of sensor nodes for collecting data, base nodes for processing collected data, relay nodes for driving devices for adjusting the environment inside greenhouse and an environment server for data storage and processing. Using the Barenbrug formula for calculating the dew point on the leaves, this system is realized to prevent dew condensation phenomena on the crop’s surface acting as an important element for prevention of diseases infections. We also constructed a physical model resembling the typical greenhouse in order to verify the performance of our system with regard to dew condensation control. PMID:22163813
Park, Dae-Heon; Park, Jang-Woo
2011-01-01
Dew condensation on the leaf surface of greenhouse crops can promote diseases caused by fungus and bacteria, affecting the growth of the crops. In this paper, we present a WSN (Wireless Sensor Network)-based automatic monitoring system to prevent dew condensation in a greenhouse environment. The system is composed of sensor nodes for collecting data, base nodes for processing collected data, relay nodes for driving devices for adjusting the environment inside greenhouse and an environment server for data storage and processing. Using the Barenbrug formula for calculating the dew point on the leaves, this system is realized to prevent dew condensation phenomena on the crop's surface acting as an important element for prevention of diseases infections. We also constructed a physical model resembling the typical greenhouse in order to verify the performance of our system with regard to dew condensation control.
Wabble gear drive mechanism. [for aerospace environments
NASA Technical Reports Server (NTRS)
Winiarski, F. J. (Inventor)
1967-01-01
The wabble gear principle was applied in the design of a driving mechanism for controlling spacecraft solar panels. The moving elements, other than the output gear, are contained within a hermetically sealed package to prevent escape of lubricants and ingestion of contaminant particles. The driving gear contains one more tooth than the output gear on a concave, conical pitch surface of slightly larger apex angle. The two gears mesh face to face such that engagement takes place at one point along the circumference. The driving gear is not permitted to rotate by virtue of its attachment through the bellows which permits flexure in the pitch and yaw position, but not in roll. As the bearing carrier rotates, the inclined mounting of the bearing causes the driving gear to perform a wabbling, irrotational motion. This wabbling motion causes the contact point between the output gear and the driving gear to traverse around the circumference of the gears once per revolution of the bearing carrier.
Design and simulation of the direct drive servo system
NASA Astrophysics Data System (ADS)
Ren, Changzhi; Liu, Zhao; Song, Libin; Yi, Qiang; Chen, Ken; Zhang, Zhenchao
2010-07-01
As direct drive technology is finding their way into telescope drive designs for its many advantages, it would push to more reliable and cheaper solutions for future telescope complex motion system. However, the telescope drive system based on the direct drive technology is one high integrated electromechanical system, which one complex electromechanical design method is adopted to improve the efficiency, reliability and quality of the system during the design and manufacture circle. The telescope is one ultra-exact, ultra-speed, high precision and huge inertial instrument, which the direct torque motor adopted by the telescope drive system is different from traditional motor. This paper explores the design process and some simulation results are discussed.
Lees, Monica N.; Cosman, Joshua D.; Lee, John D.; Rizzo, Matthew; Fricke, Nicola
2012-01-01
Neuroergonomics provides a multidisciplinary translational approach that merges elements of neuroscience, human factors, cognitive psychology, and ergonomics to study brain structure and function in everyday environments. Driving safety, particularly that of older drivers with cognitive impairments, is a fruitful application domain for neuroergonomics. Driving makes demands on multiple cognitive processes that are often studied in isolation and so presents a useful challenge in generalizing findings from controlled laboratory tasks to predict safety outcomes. Neurology and the cognitive sciences help explain the mechanisms of cognitive breakdowns that undermine driving safety. Ergonomics complements this explanation with the tools for systematically exploring the various layers of complexity that define the activity of driving. A variety of tools, such as part task simulators, driving simulators, and instrumented vehicles provide a window into cognition in the natural settings needed to assess the generalizability of laboratory findings and can provide an array of potential interventions to increase safety. PMID:21291157
The maternal-effect, selfish genetic element Medea is associated with a composite Tc1 transposon.
Lorenzen, Marcé D; Gnirke, Andreas; Margolis, Jonathan; Garnes, Jeffrey; Campbell, Margie; Stuart, Jeffrey J; Aggarwal, Rajat; Richards, Stephen; Park, Yoonseong; Beeman, Richard W
2008-07-22
Maternal-Effect Dominant Embryonic Arrest ("Medea") factors are selfish nuclear elements that combine maternal-lethal and zygotic-rescue activities to gain a postzygotic survival advantage. We show that Medea(1) activity in Tribolium castaneum is associated with a composite Tc1 transposon inserted just downstream of the neurotransmitter reuptake symporter bloated tubules (blot), whose Drosophila ortholog has both maternal and zygotic functions. The 21.5-kb insertion contains defective copies of elongation initiation factor-3, ATP synthase subunit C, and an RNaseD-related gene, as well as a potentially intact copy of a prokaryotic DUF1703 gene. Sequence comparisons suggest that the current distribution of Medea(1) reflects global emanation after a single transpositional event in recent evolutionary time. The Medea system in Tribolium represents an unusual type of intragenomic conflict and could provide a useful vehicle for driving desirable genes into populations.
The maternal-effect, selfish genetic element Medea is associated with a composite Tc1 transposon
Lorenzen, Marcé D.; Gnirke, Andreas; Margolis, Jonathan; Garnes, Jeffrey; Campbell, Margie; Stuart, Jeffrey J.; Aggarwal, Rajat; Richards, Stephen; Park, Yoonseong; Beeman, Richard W.
2008-01-01
Maternal-Effect Dominant Embryonic Arrest (“Medea”) factors are selfish nuclear elements that combine maternal-lethal and zygotic-rescue activities to gain a postzygotic survival advantage. We show that Medea1 activity in Tribolium castaneum is associated with a composite Tc1 transposon inserted just downstream of the neurotransmitter reuptake symporter bloated tubules (blot), whose Drosophila ortholog has both maternal and zygotic functions. The 21.5-kb insertion contains defective copies of elongation initiation factor-3, ATP synthase subunit C, and an RNaseD-related gene, as well as a potentially intact copy of a prokaryotic DUF1703 gene. Sequence comparisons suggest that the current distribution of Medea1 reflects global emanation after a single transpositional event in recent evolutionary time. The Medea system in Tribolium represents an unusual type of intragenomic conflict and could provide a useful vehicle for driving desirable genes into populations. PMID:18621706
Designing for Maintainability and System Availability
NASA Technical Reports Server (NTRS)
Lalli, Vincent R.; Packard, Michael H.
1997-01-01
The final goal for a delivered system (whether a car, aircraft, avionics box or computer) should be its availability to operate and perform its intended function over its expected design life. Hence, in designing a system, we cannot think in terms of delivering the system and just walking away. The system supplier needs to provide support throughout the operating life of the product. Here, supportability requires an effective combination of reliability, maintainability, logistics and operations engineering (as well as safety engineering) to have a system that is available for its intended use throughout its designated mission lifetime. Maintainability is a key driving element in the effective support and upkeep of the system as well as providing the ability to modify and upgrade the system throughout its lifetime. This paper then, will concentrate on maintainability and its integration into the system engineering and design process. The topics to be covered include elements of maintainability, the total cost of ownership, how system availability, maintenance and logistics costs and spare parts cost effect the overall program costs. System analysis and maintainability will show how maintainability fits into the overall systems approach to project development. Maintainability processes and documents will focus on how maintainability is to be performed and what documents are typically generated for a large scale program. Maintainability analysis shows how trade-offs can be performed for various alternative components. The conclusions summarize the paper and are followed by specific problems for hands-on training.
14 CFR 27.923 - Rotor drive system and control mechanism tests.
Code of Federal Regulations, 2011 CFR
2011-01-01
... purpose of this paragraph, an affected power input includes all parts of the rotor drive system which can... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Rotor drive system and control mechanism... TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: NORMAL CATEGORY ROTORCRAFT Powerplant Rotor Drive System § 27...
14 CFR 27.923 - Rotor drive system and control mechanism tests.
Code of Federal Regulations, 2013 CFR
2013-01-01
... purpose of this paragraph, an affected power input includes all parts of the rotor drive system which can... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Rotor drive system and control mechanism... TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: NORMAL CATEGORY ROTORCRAFT Powerplant Rotor Drive System § 27...
DOT National Transportation Integrated Search
1998-04-01
The effect on driving performance of using a speed, steering, and gap control system (SSGCS) and a collision warning system (CWS) was assessed in an experiment conducted in the Iowa Driving Simulator. Driving performance data were obtained from 52 dr...
14 CFR 27.923 - Rotor drive system and control mechanism tests.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Rotor drive system and control mechanism....923 Rotor drive system and control mechanism tests. (a) Each part tested as prescribed in this section... affect test results may be conducted. (b) Each rotor drive system and control mechanism must be tested...
14 CFR 27.923 - Rotor drive system and control mechanism tests.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Rotor drive system and control mechanism....923 Rotor drive system and control mechanism tests. (a) Each part tested as prescribed in this section... affect test results may be conducted. (b) Each rotor drive system and control mechanism must be tested...
Cell-microenvironment interactions and architectures in microvascular systems
Bersini, Simone; Yazdi, Iman K.; Talò, Giuseppe; Shin, Su Ryon; Moretti, Matteo; Khademhosseini, Ali
2016-01-01
In the past decade, significant advances have been made in the design and optimization of novel biomaterials and microfabrication techniques to generate vascularized tissues. Novel microfluidic systems have facilitated the development and optimization of in vitro models for exploring the complex pathophysiological phenomena that occur inside a microvascular environment. To date, most of these models have focused on engineering of increasingly complex systems, rather than analyzing the molecular and cellular mechanisms that drive microvascular network morphogenesis and remodeling. In fact, mutual interactions among endothelial cells (ECs), supporting mural cells and organ-specific cells, as well as between ECs and the extracellular matrix, are key driving forces for vascularization. This review focuses on the integration of materials science, microengineering and vascular biology for the development of in vitro microvascular systems. Various approaches currently being applied to study cell-cell/cell-matrix interactions, as well as biochemical/biophysical cues promoting vascularization and their impact on microvascular network formation, will be identified and discussed. Finally, this review will explore in vitro applications of microvascular systems, in vivo integration of transplanted vascularized tissues, and the important challenges for vascularization and controlling the microcirculatory system within the engineered tissues, especially for microfabrication approaches. It is likely that existing models and more complex models will further our understanding of the key elements of vascular network growth, stabilization and remodeling to translate basic research principles into functional, vascularized tissue constructs for regenerative medicine applications, drug screening and disease models. PMID:27417066
Cell-microenvironment interactions and architectures in microvascular systems.
Bersini, Simone; Yazdi, Iman K; Talò, Giuseppe; Shin, Su Ryon; Moretti, Matteo; Khademhosseini, Ali
2016-11-01
In the past decade, significant advances have been made in the design and optimization of novel biomaterials and microfabrication techniques to generate vascularized tissues. Novel microfluidic systems have facilitated the development and optimization of in vitro models for exploring the complex pathophysiological phenomena that occur inside a microvascular environment. To date, most of these models have focused on engineering of increasingly complex systems, rather than analyzing the molecular and cellular mechanisms that drive microvascular network morphogenesis and remodeling. In fact, mutual interactions among endothelial cells (ECs), supporting mural cells and organ-specific cells, as well as between ECs and the extracellular matrix, are key driving forces for vascularization. This review focuses on the integration of materials science, microengineering and vascular biology for the development of in vitro microvascular systems. Various approaches currently being applied to study cell-cell/cell-matrix interactions, as well as biochemical/biophysical cues promoting vascularization and their impact on microvascular network formation, will be identified and discussed. Finally, this review will explore in vitro applications of microvascular systems, in vivo integration of transplanted vascularized tissues, and the important challenges for vascularization and controlling the microcirculatory system within the engineered tissues, especially for microfabrication approaches. It is likely that existing models and more complex models will further our understanding of the key elements of vascular network growth, stabilization and remodeling to translate basic research principles into functional, vascularized tissue constructs for regenerative medicine applications, drug screening and disease models. Copyright © 2016 Elsevier Inc. All rights reserved.
Space Launch System (SLS) Safety, Mission Assurance, and Risk Mitigation
NASA Technical Reports Server (NTRS)
May, Todd
2013-01-01
SLS Driving Objectives: I. Safe: a) Human-rated to provide safe and reliable systems for human missions. b) Protecting the public, NASA workforce, high-value equipment and property, and the environment from potential harm. II. Affordable: a) Maximum use of common elements and existing assets, infrastructure, and workforce. b) Constrained budget environment. c) Competitive opportunities for affordability on-ramps. III. Sustainable: a) Initial capability: 70 metric tons (t), 2017-2021. 1) Serves as primary transportation for Orion and exploration missions. 2) Provides back-up capability for crew/cargo to ISS. b) Evolved capability: 105 t and 130 t, post-2021. 1) Offers large volume for science missions and payloads. 2) Modular and flexible, right-sized for mission requirements.
Emotions are emergent processes: they require a dynamic computational architecture
Scherer, Klaus R.
2009-01-01
Emotion is a cultural and psychobiological adaptation mechanism which allows each individual to react flexibly and dynamically to environmental contingencies. From this claim flows a description of the elements theoretically needed to construct a virtual agent with the ability to display human-like emotions and to respond appropriately to human emotional expression. This article offers a brief survey of the desirable features of emotion theories that make them ideal blueprints for agent models. In particular, the component process model of emotion is described, a theory which postulates emotion-antecedent appraisal on different levels of processing that drive response system patterning predictions. In conclusion, investing seriously in emergent computational modelling of emotion using a nonlinear dynamic systems approach is suggested. PMID:19884141
A review of physical security robotics at Sandia National Laboratories
DOE Office of Scientific and Technical Information (OSTI.GOV)
Roerig, S.C.
1990-01-01
As an outgrowth of research into physical security technologies, Sandia is investigating the role of robotics in security systems. Robotics may allow more effective utilization of guard forces, especially in scenarios where personnel would be exposed to harmful environments. Robots can provide intrusion detection and assessment functions for failed sensors or transient assets, can test existing fixed site sensors, and can gather additional intelligence and dispense delaying elements. The Robotic Security Vehicle (RSV) program for DOE/OSS is developing a fieldable prototype for an exterior physical security robot based upon a commercial four wheel drive vehicle. The RSV will be capablemore » of driving itself, being driven remotely, or being driven by an onboard operator around a site and will utilize its sensors to alert an operator to unusual conditions. The Remote Security Station (RSS) program for the Defense Nuclear Agency is developing a proof-of-principle robotic system which will be used to evaluate the role, and associated cost, of robotic technologies in exterior security systems. The RSS consists of an independent sensor pod, a mobile sensor platform and a control and display console. Sensor data fusion is used to optimize the system's intrusion detection performance. These programs are complementary, the RSV concentrates on developing autonomous mobility, while the RSS thrust is on mobile sensor employment. 3 figs.« less
Mechanical-thermal noise in drive-mode of a silicon micro-gyroscope.
Yang, Bo; Wang, Shourong; Li, Hongsheng; Zhou, Bailing
2009-01-01
A new closed-loop drive scheme which decouples the phase and the gain of the closed-loop driving system was designed in a Silicon Micro-Gyroscope (SMG). We deduce the system model of closed-loop driving and use stochastic averaging to obtain an approximate "slow" system that clarifies the effect of thermal noise. The effects of mechanical-thermal noise on the driving performance of the SMG, including the noise spectral density of the driving amplitude and frequency, are derived. By calculating and comparing the noise amplitude due to thermal noise both in the opened-loop driving and in the closed-loop driving, we find that the closed-loop driving does not reduce the RMS noise amplitude. We observe that the RMS noise frequency can be reduced by increasing the quality factor and the drive amplitude in the closed-loop driving system. The experiment and simulation validate the feasibility of closed-loop driving and confirm the validity of the averaged equation and its stablility criterion. The experiment and simulation results indicate the electrical noise of closed-loop driving circuitry is bigger than the mechanical-thermal noise and as the driving mass decreases, the mechanical-thermal noise may get bigger than the electrical noise of the closed-loop driving circuitry.
Prazak, Lisa; Fujioka, Miki; Gergen, J. Peter
2010-01-01
The relatively simple combinatorial rules responsible for establishing the initial metameric expression of sloppy-paired-1 (slp1) in the Drosophila blastoderm embryo make this system an attractive model for investigating the mechanism of regulation by pair rule transcription factors. This investigation of slp1 cis-regulatory architecture identifies two distinct elements, a proximal early stripe element (PESE) and a distal early stripe element (DESE) located from −3.1 kb to −2.5 kb and from −8.1 kb to −7.1 kb upstream of the slp1 promoter, respectively, that mediate this early regulation. The proximal element expresses only even-numbered stripes and mediates repression by Even-skipped (Eve) as well as by the combination of Runt and Fushi-tarazu (Ftz). A 272 basepair sub-element of PESE retains Eve-dependent repression, but is expressed throughout the even-numbered parasegments due to the loss of repression by Runt and Ftz. In contrast, the distal element expresses both odd and even-numbered stripes and also drives inappropriate expression in the anterior half of the odd-numbered parasegments due to an inability to respond to repression by Eve. Importantly, a composite reporter gene containing both early stripe elements recapitulates pair-rule gene-dependent regulation in a manner beyond what is expected from combining their individual patterns. These results indicate interactions involving distinct cis-elements contribute to the proper integration of pair-rule regulatory information. A model fully accounting for these results proposes that metameric slp1 expression is achieved through the Runt-dependent regulation of interactions between these two pair-rule response elements and the slp1 promoter. PMID:20435028
Gallo-Ebert, Christina; Donigan, Melissa; Liu, Hsing-Yin; Pascual, Florencia; Manners, Melissa; Pandya, Devanshi; Swanson, Robert; Gallagher, Denise; Chen, WeiWei; Carman, George M.; Nickels, Joseph T.
2013-01-01
Saccharomyces cerevisiae ergosterol biosynthesis, like cholesterol biosynthesis in mammals, is regulated at the transcriptional level by a sterol feedback mechanism. Yeast studies defined a 7-bp consensus sterol-response element (SRE) common to genes involved in sterol biosynthesis and two transcription factors, Upc2 and Ecm22, which direct transcription of sterol biosynthetic genes. The 7-bp consensus SRE is identical to the anaerobic response element, AR1c. Data indicate that Upc2 and Ecm22 function through binding to this SRE site. We now show that it is two novel anaerobic AR1b elements in the UPC2 promoter that direct global ERG gene expression in response to a block in de novo ergosterol biosynthesis, brought about by antifungal drug treatment. The AR1b elements are absolutely required for auto-induction of UPC2 gene expression and protein and require Upc2 and Ecm22 for function. We further demonstrate the direct binding of recombinant expressed S. cerevisiae ScUpc2 and pathogenic Candida albicans CaUpc2 and Candida glabrata CgUpc2 to AR1b and SRE/AR1c elements. Recombinant endogenous promoter studies show that the UPC2 anaerobic AR1b elements act in trans to regulate ergosterol gene expression. Our results indicate that Upc2 must occupy UPC2 AR1b elements in order for ERG gene expression induction to take place. Thus, the two UPC2-AR1b elements drive expression of all ERG genes necessary for maintaining normal antifungal susceptibility, as wild type cells lacking these elements have increased susceptibility to azole antifungal drugs. Therefore, targeting these specific sites for antifungal therapy represents a novel approach to treat systemic fungal infections. PMID:24163365
Physics-Based Computational Algorithm for the Multi-Fluid Plasma Model
2014-06-30
applying it to study laser - 20 Physics-Based Multi-Fluid Plasma Algorithm Shumlak Figure 6: Blended finite element method applied to the species...separation problem in capsule implosions. Number densities and electric field are shown after the laser drive has compressed the multi-fluid plasma and...6 after the laser drive has started the compression. A separation clearly develops. The solution is found using an explicit advance (CFL=1) for the
Electromagnetic or other directed energy pulse launcher
Ziolkowski, Richard W.
1990-01-01
The physical realization of new solutions of wave propagation equations, such as Maxwell's equations and the scaler wave equation, produces localized pulses of wave energy such as electromagnetic or acoustic energy which propagate over long distances without divergence. The pulses are produced by driving each element of an array of radiating sources with a particular drive function so that the resultant localized packet of energy closely approximates the exact solutions and behaves the same.
Rock geochemistry induces stress and starvation responses in the bacterial proteome.
Bryce, Casey C; Le Bihan, Thierry; Martin, Sarah F; Harrison, Jesse P; Bush, Timothy; Spears, Bryan; Moore, Alanna; Leys, Natalie; Byloos, Bo; Cockell, Charles S
2016-04-01
Interactions between microorganisms and rocks play an important role in Earth system processes. However, little is known about the molecular capabilities microorganisms require to live in rocky environments. Using a quantitative label-free proteomics approach, we show that a model bacterium (Cupriavidus metallidurans CH34) can use volcanic rock to satisfy some elemental requirements, resulting in increased rates of cell division in both magnesium- and iron-limited media. However, the rocks also introduced multiple new stresses via chemical changes associated with pH, elemental leaching and surface adsorption of nutrients that were reflected in the proteome. For example, the loss of bioavailable phosphorus was observed and resulted in the upregulation of diverse phosphate limitation proteins, which facilitate increase phosphate uptake and scavenging within the cell. Our results revealed that despite the provision of essential elements, rock chemistry drives complex metabolic reorganization within rock-dwelling organisms, requiring tight regulation of cellular processes at the protein level. This study advances our ability to identify key microbial responses that enable life to persist in rock environments. © 2015 Society for Applied Microbiology and John Wiley & Sons Ltd.
Rusk, B.G.; Lowers, H.A.; Reed, M.H.
2008-01-01
High-resolution electron microprobe maps show the distribution of Ti, Al, Ca, K, and Fe among quartz growth zones revealed by scanning electron microscope-cathodoluminescence (SEM-CL) from 12 hydrothermal ore deposits formed between ???100 and e1750 ??C. The maps clearly show the relationships between trace elements and CL intensity in quartz. Among all samples, no single trace element consistently correlates with variations in CL intensity. However in vein quartz from five porphyry-Cu (Mo-Au) deposits, CL intensity always correlates positively with Ti concentrations, suggesting that Ti is a CL activator in quartz formed at >400 ??C. Ti concentrations in most rutile-bearing vein quartz from porphyry copper deposits indicate reasonable formation temperatures of 2000 ppm, but in high-temperature quartz, Al concentrations are consistently in the range of several hundred ppm. Aluminum concentrations in quartz refl ect the Al solubility in hydrothermal fluids, which is strongly dependent on pH. Aluminum concentrations in quartz therefore reflect fluctuations in pH that may drive metal-sulfide precipitation in hydrothermal systems. ?? 2008 The Geological Society of America.
NASA Technical Reports Server (NTRS)
Cameron, Kenneth D.; Gentz, Steven J.; Beil, Robert J.; Minute, Stephen A.; Currie, Nancy J.; Scott, Steven S.; Thomas, Walter B., III; Smiles, Michael D.; Schafer, Charles F.; Null, Cynthia H.;
2009-01-01
At the request of the Exploration Systems Mission Directorate (ESMD) and the Constellation Program (CxP) Safety, Reliability; and Quality Assurance (SR&QA) Requirements Director, the NASA Engineering and Safety Center (NESC) participated in the Cx SR&QA Requirements forum. The Requirements Forum was held June 24-26; 2008, at GRC's Plum Brook Facility. The forums purpose was to gather all stakeholders into a focused meeting to help complete the process of refining the CxP to refine its Level II SR&QA requirements or defining project-specific requirements tailoring. Element prime contractors had raised specific questions about the wording and intent of many requirements in areas they felt were driving costs without adding commensurate value. NESC was asked to provide an independent and thorough review of requirements that contractors believed were driving Program costs, by active participation in the forum. This document contains information from the forum.
Proposal of a new electromechanical total artificial heart: the TAH Serpentina.
Sauer, I M; Frank, J; Bücherl, E S
1999-03-01
A new type of energy converter for an electro-mechanical total artificial heart (TAH) based on the principle of a unidirectional moving motor is described. Named the TAH Serpentina, the concept consists of 2 major parts, a pendulum shaped movable element fixed on one side using a joint bearing and a special shaped drum cam. Pusher plates are mounted flexibly to the crossbar of the pendulum. A motor drives the special shaped drum cam linked to the pendulum through a ball bearing. The circular motion of the unidirectional moving brushless DC motor is transferred into the linear motion of the pendulum to drive the pusher plates. Using a crossbar with a variable length, the stroke of the pendulum and therefore the displaced blood volume is alterable. To achieve a variable length, an electric driven screw thread or a hydraulic system is possible. Comparable to the natural heart, cardiac output would be determined by frequency and stroke volume.
NASA Astrophysics Data System (ADS)
Seki, Hirokazu; Sugimoto, Takeaki; Tadakuma, Susumu
This paper describes a novel straight road driving control scheme of power assisted wheelchair. Power assisted wheelchair which assists the driving force by electric motors is expected to be widely used as a mobility support system for elderly people and disabled people. The straight driving can be prevented by the road conditions such as branches, grass and carpets because the right and left wheels drive independently. This paper proposes a straight road driving control system based on the disturbance torque estimation. The proposed system estimates the difference of the driving torque by disturbance torque observer and compensates to one side of the wheels. Some practical driving experiments on various road conditions show the effectiveness of the proposed control system.
Electronic Medical Record Documentation of Driving Safety for Veterans with Diagnosed Dementia.
Vair, Christina L; King, Paul R; Gass, Julie; Eaker, April; Kusche, Anna; Wray, Laura O
2018-01-01
Many older adults continue to drive following dementia diagnosis, with medical providers increasingly likely to be involved in addressing such safety concerns. This study examined electronic medical record (EMR) documentation of driving safety for veterans with dementia (N = 118) seen in Veterans Affairs primary care and interdisciplinary geriatrics clinics in one geographic region over a 10-year period. Qualitative directed content analysis of retrospective EMR data. Assessment of known risk factors or subjective concerns for unsafe driving were documented in fewer than half of observed cases; specific recommendations for driving safety were evident for a minority of patients, with formal driving evaluation the most frequently documented recommendation by providers. Utilizing data from actual clinical encounters provides a unique snapshot of how driving risk and safety concerns are addressed for veterans with dementia. This information provides a meaningful frame of reference for understanding potential strengths and possible gaps in how this important topic area is being addressed in the course of clinical care. The EMR is an important forum for interprofessional communication, with documentation of driving risk and safety concerns an essential element for continuity of care and ensuring consistency of information delivered to patients and caregivers.
Carvalho, Janessa O; Springate, Beth; Bernier, Rachel A; Davis, Jennifer
2018-03-01
ABSTRACTBackground:The American Academy of Neurology (AAN) updated their practice parameters in the evaluation of driving risk in dementia and developed a Caregiver Driving Safety Questionnaire, detailed in their original manuscript (Iverson Gronseth, Reger, Classen, Dubinsky, & Rizzo, 2010). They described four factors associated with decreased driving ability in dementia patients: history of crashes or citations, informant-reported concerns, reduced mileage, and aggressive driving. An informant-reported AAN Caregiver Driving Safety Questionnaire was designed with these elements, and the current study was the first to explore the factor structure of this questionnaire. Additionally, we examined associations between these factors and cognitive and behavioral measures in patients with mild cognitive impairment or early Alzheimer's disease and their informants. Exploratory factor analysis revealed a four-component structure, consistent with the theory behind the AAN scale composition. These four factor scores also were significantly associated with performance on cognitive screening instruments and informant reported behavioral dysfunction. Regressions revealed that behavioral dysfunction predicted caregiver concerns about driving safety beyond objective patient cognitive dysfunction. In this first known quantitative exploration of the scale, our results support continued use of this scale in office driving safety assessments. Additionally, patient behavioral changes predicted caregiver concerns about driving safety over and above cognitive status, which suggests that caregivers may benefit from psychoeducation about cognitive factors that may negatively impact driving safety.
Optimization of an electromagnetic linear actuator using a network and a finite element model
NASA Astrophysics Data System (ADS)
Neubert, Holger; Kamusella, Alfred; Lienig, Jens
2011-03-01
Model based design optimization leads to robust solutions only if the statistical deviations of design, load and ambient parameters from nominal values are considered. We describe an optimization methodology that involves these deviations as stochastic variables for an exemplary electromagnetic actuator used to drive a Braille printer. A combined model simulates the dynamic behavior of the actuator and its non-linear load. It consists of a dynamic network model and a stationary magnetic finite element (FE) model. The network model utilizes lookup tables of the magnetic force and the flux linkage computed by the FE model. After a sensitivity analysis using design of experiment (DoE) methods and a nominal optimization based on gradient methods, a robust design optimization is performed. Selected design variables are involved in form of their density functions. In order to reduce the computational effort we use response surfaces instead of the combined system model obtained in all stochastic analysis steps. Thus, Monte-Carlo simulations can be applied. As a result we found an optimum system design meeting our requirements with regard to function and reliability.
NASA Technical Reports Server (NTRS)
Litvin, Faydor L.; Nava, Alessandro; Fan, Qi; Fuentes, Alfonso
2002-01-01
New geometry of face worm gear drives with conical and cylindrical worms is proposed. The generation of the face worm-gear is based on application of a tilted head-cutter (grinding tool) instead of application of a hob applied at present. The generation of a conjugated worm is based on application of a tilted head-cutter (grinding tool) as well. The bearing contact of the gear drive is localized and is oriented longitudinally. A predesigned parabolic function of transmission errors for reduction of noise and vibration is provided. The stress analysis of the gear drive is performed using a three-dimensional finite element analysis. The contacting model is automatically generated. The developed theory is illustrated with numerical examples.
System analysis of graphics processor architecture using virtual prototyping
NASA Astrophysics Data System (ADS)
Hancock, William R.; Groat, Jeff; Steeves, Todd; Spaanenburg, Henk; Shackleton, John
1995-06-01
Honeywell has been actively involved in the definition of the next generation display processors for military and commercial cockpits. A major concern is how to achieve super graphics workstation performance in avionics application. Most notable are requirements for low volume, low power, harsh environmental conditions, real-time performance and low cost. This paper describes the application of VHDL to the system analysis tasks associated with achieving these goals in a cost effective manner. The paper will describe the top level architecture identified to provide the graphical and video processing power needed to drive future high resolution display devices and to generate more natural panoramic 3D formats. The major discussion, however, will be on the use of VHDL to model the processing elements and customized pipelines needed to realize the architecture and for doing the complex system tradeoff studies necessary to achieve a cost effective implementation. New software tools have been developed to allow 'virtual' prototyping in the VHDL environment. This results in a hardware/software codesign using VHDL performance and functional models. This unique architectural tool allows simulation and tradeoffs within a standard and tightly integrated toolset, which eventually will be used to specify and design the entire system from the top level requirements and system performance to the lowest level individual ASICs. New processing elements, algorithms, and standard graphical inputs can be designed, tested and evaluated without the costly hardware prototyping using the innovative 'virtual' prototyping techniques which are evolving on this project. In addition, virtual prototyping of the display processor does not bind the preliminary design to point solutions as a physical prototype will. when the development schedule is known, one can extrapolate processing elements performance and design the system around the most current technology.
NASA Astrophysics Data System (ADS)
Stay, Justin L.; Carr, Dustin; Ferguson, Steve; Haber, Todd; Jenkins, Robert; Mock, Joel
2017-02-01
Optical coherence tomography (OCT) has become a useful and common diagnostic tool within the field of ophthalmology. Although presently a commercial technology, research continues in improving image quality and applying the imaging method to other tissue types. Swept-wavelength lasers based upon fiber ring cavities containing fiber Fabry-Ṕerot tunable filters (FFP-TF), as an intracavity element, provide swept-source optical coherence tomography (SS-OCT) systems with a robust and scalable platform. The FFP-TF can be fabricated within a large range of operating wavelengths, free spectral ranges (FSR), and finesses. To date, FFP-TFs have been fabricated at operating wavelengths from 400 nm to 2.2 µm, FSRs as large as 45 THz, and finesses as high as 30 000. The results in this paper focus on presenting the capability of the FFP-TF as an intracavity element in producing swept-wavelength lasers sources and quantifying the trade off between coherence length and sweep range. We present results within a range of feasible operating conditions. Particular focus is given to the discovery of laser configurations that result in maximization of sweep range and/or power. A novel approach to the electronic drive of the PZT-based FFP-TF is also presented, which eliminates the need for the existence of a mechanical resonance of the optical device. This approach substantially increases the range of drive frequencies with which the filter can be driven and has a positive impact for both the short all-fiber laser cavity (presented in this paper) and long cavity FDML designs as well.
Melt Heterogeneity and Degassing at MT Etna from Melt Inclusions
NASA Astrophysics Data System (ADS)
Salem, L. C.; Edmonds, M.; Maclennan, J.; Corsaro, R. A.
2014-12-01
The melts feeding Mt Etna, Italy, are rich in volatiles and drive long-lasting powerful eruptions of basaltic magma in both effusive and explosive styles of activity. The volatile systematics of the volcanic system are well understood through melt inclusion and volcanic gas studies. Etna's melts are generated from a complex mantle setting, with subduction-related chemical modifications as well as OIB-type features, and then the melts must travel through thick carbonate-rich crust. The continual influx of mantle-derived volatile-rich magma controls the major compositional and eruptive features of Mount Etna and magma mixing has been recognized as an important process driving large eruptions [Kamenetsky, 2007]. Our study focusses on the 1669 eruption, the largest in historical times. Olivine-hosted melt inclusions were analyzed for volatile, trace and major elements using electron microprobe and ion probe (SIMS). We use volatile systematics and geochemical data to deconvolve mantle-derived heterogeneity from melt mixing and crystal fractionation. Our data are well described by a mixing trend between two distinct melts: a CO2-rich (CO2~1000ppm), incompatible trace element depleted melt (La/Yb~16), and a CO2-poor, enriched melt. The mixing also generates a strong correlation between Sr and CO2 in the melt inclusions dataset, reflecting the presence of a strong Sr anomaly in one of the end-member melts. We investigate the origin of this Sr anomaly by considering plagioclase dissolution and crustal assimilation. We also investigate degassing processes in the crust and plumbing system of the volcano. We compare our results with similar studies of OIB and arc-related basalts elsewhere and assess the implications for linking eruption size and style with the nature of the mantle-derived melts. Kamenetsky et al. (2007) Geology 35, 255-258.
Satir, Sarp; Zahorian, Jaime; Degertekin, F. Levent
2014-01-01
A large signal, transient model has been developed to predict the output characteristics of a CMUT array operated in the non-collapse mode. The model is based on separation of the nonlinear electrostatic voltage-to-force relation and the linear acoustic array response. For linear acoustic radiation and crosstalk effects, the boundary element method is used. The stiffness matrix in the vibroacoustics calculations is obtained using static finite element analysis of a single membrane which can have arbitrary geometry and boundary conditions. A lumped modeling approach is used to reduce the order of the system for modeling the transient nonlinear electrostatic actuation. To accurately capture the dynamics of the non-uniform electrostatic force distribution over the CMUT electrode during large deflections, the membrane electrode is divided into patches shaped to match higher order membrane modes, each introducing a variable to the system model. This reduced order nonlinear lumped model is solved in the time domain using Simulink. The model has two linear blocks to calculate the displacement profile of the electrode patches and the output pressure for a given force distribution over the array, respectively. The force to array displacement block uses the linear acoustic model, and the Rayleigh integral is evaluated to calculate the pressure at any field point. Using the model, the transient transmitted pressure can be simulated for different large signal drive signal configurations. The acoustic model is verified by comparison to harmonic FEA in vacuum and fluid for high and low aspect ratio membranes as well as mass-loaded membranes. The overall Simulink model is verified by comparison to transient 3D FEA and experimental results for different large drive signals; and an example for a phased array simulation is given. PMID:24158297
Integrated HIFU Drive System on a Chip for CMUT-Based Catheter Ablation System.
Farhanieh, Omid; Sahafi, Ali; Bardhan Roy, Rupak; Ergun, Arif Sanli; Bozkurt, Ayhan
2017-06-01
Conventional High Intensity Focused Ultrasound (HIFU) is a therapeutic modality which is extracorporeally administered. In applications where a relatively small HIFU lesion is required, an intravascular HIFU probe can be deployed to the ablation site. In this paper, we demonstrate the design and implementation a fully integrated HIFU drive system on a chip to be placed on a 6 Fr catheter probe. An 8-element capacitive micromachined ultrasound transducer (CMUT) ring array of 2 mm diameter has been used as the ultrasound source. The driver chip is fabricated in 0.35 μm AMS high-voltage CMOS technology and comprises eight continuous-wave (CW) high-voltage CMUT drivers (10.9 ns and 9.4 ns rise and fall times at 20 V pp output into a 15 pF), an eight-channel digital beamformer (8-12 MHz output frequency with 11.25 ° phase accuracy) and a phase locked loop with an integrated VCO as a tunable clock source (128-192 MHz). The chip occupies 1.85 × 1.8 mm 2 area including input and output (I/O) pads. When the transducer array is immersed in sunflower oil and driven by the IC with eight 20 V pp CW pulses at 10 MHz, real-time thermal images of the HIFU beam indicate that the focal temperature rises by 16.8 ° C in 11 seconds. Each HV driver consumes around 67 mW of power when driving the CMUT array at 10 MHz, which adds up to 560 mW for the whole chip. FEM based analysis reveals that the outer surface temperature of the catheter is expected to remain below the 42 ° C tissue damage limit during therapy.
Local, regional and national interoperability in hospital-level systems architecture.
Mykkänen, J; Korpela, M; Ripatti, S; Rannanheimo, J; Sorri, J
2007-01-01
Interoperability of applications in health care is faced with various needs by patients, health professionals, organizations and policy makers. A combination of existing and new applications is a necessity. Hospitals are in a position to drive many integration solutions, but need approaches which combine local, regional and national requirements and initiatives with open standards to support flexible processes and applications on a local hospital level. We discuss systems architecture of hospitals in relation to various processes and applications, and highlight current challenges and prospects using a service-oriented architecture approach. We also illustrate these aspects with examples from Finnish hospitals. A set of main services and elements of service-oriented architectures for health care facilities are identified, with medium-term focus which acknowledges existing systems as a core part of service-oriented solutions. The services and elements are grouped according to functional and interoperability cohesion. A transition towards service-oriented architecture in health care must acknowledge existing health information systems and promote the specification of central processes and software services locally and across organizations. Software industry best practices such as SOA must be combined with health care knowledge to respond to central challenges such as continuous change in health care. A service-oriented approach cannot entirely rely on common standards and frameworks but it must be locally adapted and complemented.
Decoupling Identification for Serial Two-Link Two-Inertia System
NASA Astrophysics Data System (ADS)
Oaki, Junji; Adachi, Shuichi
The purpose of our study is to develop a precise model by applying the technique of system identification for the model-based control of a nonlinear robot arm, under taking joint-elasticity into consideration. We previously proposed a systematic identification method, called “decoupling identification,” for a “SCARA-type” planar two-link robot arm with elastic joints caused by the Harmonic-drive® reduction gears. The proposed method serves as an extension of the conventional rigid-joint-model-based identification. The robot arm is treated as a serial two-link two-inertia system with nonlinearity. The decoupling identification method using link-accelerometer signals enables the serial two-link two-inertia system to be divided into two linear one-link two-inertia systems. The MATLAB®'s commands for state-space model estimation are utilized in the proposed method. Physical parameters such as motor inertias, link inertias, joint-friction coefficients, and joint-spring coefficients are estimated through the identified one-link two-inertia systems using a gray-box approach. This paper describes accuracy evaluations using the two-link arm for the decoupling identification method under introducing closed-loop-controlled elements and varying amplitude-setup of identification-input. Experimental results show that the identification method also works with closed-loop-controlled elements. Therefore, the identification method is applicable to a “PUMA-type” vertical robot arm under gravity.
NASA Astrophysics Data System (ADS)
Kam, Winnie; Liacos, James W.; Schauer, James J.; Delfino, Ralph J.; Sioutas, Constantinos
2012-12-01
An on-road sampling campaign was conducted on two major surface streets (Wilshire and Sunset Boulevards) in Los Angeles, CA, to characterize PM components including metals, trace elements, and organic species for three PM size fractions (PM10-2.5, PM2.5-0.25, and PM0.25). Fuel-based emission factors (mass of pollutant per kg of fuel) were calculated to assess the emissions profile of a light-duty vehicle (LDV) traffic fleet characterized by stop-and-go driving conditions that are reflective of urban street driving. Emission factors for metals and trace elements were highest in PM10-2.5 while emission factors for PAHs and hopanes and steranes were highest in PM0.25. PM2.5 emission factors were also compared to previous freeway, roadway tunnel, and dynamometer studies based on an LDV fleet to determine how various environments and driving conditions may influence concentrations of PM components. The on-road sampling methodology deployed in the current study captured substantially higher levels of metals and trace elements associated with vehicular abrasion (Fe, Ca, Cu, and Ba) and crustal origins (Mg and Al) than previous LDV studies. The semi-volatile nature of PAHs resulted in higher levels of PAHs in the particulate phase for LDV tunnel studies (Phuleria et al., 2006) and lower levels of PAHs in the particulate phase for freeway studies (Ning et al., 2008). With the exception of a few high molecular weight PAHs, the current study's emission factors were in between the LDV tunnel and LDV freeway studies. In contrast, hopane and sterane emission factors were generally comparable between the current study, the LDV tunnel, and LDV freeway, as expected given the greater atmospheric stability of these organic compounds. Overall, the emission factors from the dynamometer studies for metals, trace elements, and organic species are lower than the current study. Lastly, n-alkanes (C19-C40) were quantified and alkane carbon preference indices (CPIs) were determined to be in the range of 1-2, indicating substantial anthropogenic source contribution for surface streets in Los Angeles.
Segers, L S; Nuding, S C; Ott, M M; Dean, J B; Bolser, D C; O'Connor, R; Morris, K F; Lindsey, B G
2015-01-01
Models of brain stem ventral respiratory column (VRC) circuits typically emphasize populations of neurons, each active during a particular phase of the respiratory cycle. We have proposed that "tonic" pericolumnar expiratory (t-E) neurons tune breathing during baroreceptor-evoked reductions and central chemoreceptor-evoked enhancements of inspiratory (I) drive. The aims of this study were to further characterize the coordinated activity of t-E neurons and test the hypothesis that peripheral chemoreceptors also modulate drive via inhibition of t-E neurons and disinhibition of their inspiratory neuron targets. Spike trains of 828 VRC neurons were acquired by multielectrode arrays along with phrenic nerve signals from 22 decerebrate, vagotomized, neuromuscularly blocked, artificially ventilated adult cats. Forty-eight of 191 t-E neurons fired synchronously with another t-E neuron as indicated by cross-correlogram central peaks; 32 of the 39 synchronous pairs were elements of groups with mutual pairwise correlations. Gravitational clustering identified fluctuations in t-E neuron synchrony. A network model supported the prediction that inhibitory populations with spike synchrony reduce target neuron firing probabilities, resulting in offset or central correlogram troughs. In five animals, stimulation of carotid chemoreceptors evoked changes in the firing rates of 179 of 240 neurons. Thirty-two neuron pairs had correlogram troughs consistent with convergent and divergent t-E inhibition of I cells and disinhibitory enhancement of drive. Four of 10 t-E neurons that responded to sequential stimulation of peripheral and central chemoreceptors triggered 25 cross-correlograms with offset features. The results support the hypothesis that multiple afferent systems dynamically tune inspiratory drive in part via coordinated t-E neurons. Copyright © 2015 the American Physiological Society.
Segers, L. S.; Nuding, S. C.; Ott, M. M.; Dean, J. B.; Bolser, D. C.; O'Connor, R.; Morris, K. F.
2014-01-01
Models of brain stem ventral respiratory column (VRC) circuits typically emphasize populations of neurons, each active during a particular phase of the respiratory cycle. We have proposed that “tonic” pericolumnar expiratory (t-E) neurons tune breathing during baroreceptor-evoked reductions and central chemoreceptor-evoked enhancements of inspiratory (I) drive. The aims of this study were to further characterize the coordinated activity of t-E neurons and test the hypothesis that peripheral chemoreceptors also modulate drive via inhibition of t-E neurons and disinhibition of their inspiratory neuron targets. Spike trains of 828 VRC neurons were acquired by multielectrode arrays along with phrenic nerve signals from 22 decerebrate, vagotomized, neuromuscularly blocked, artificially ventilated adult cats. Forty-eight of 191 t-E neurons fired synchronously with another t-E neuron as indicated by cross-correlogram central peaks; 32 of the 39 synchronous pairs were elements of groups with mutual pairwise correlations. Gravitational clustering identified fluctuations in t-E neuron synchrony. A network model supported the prediction that inhibitory populations with spike synchrony reduce target neuron firing probabilities, resulting in offset or central correlogram troughs. In five animals, stimulation of carotid chemoreceptors evoked changes in the firing rates of 179 of 240 neurons. Thirty-two neuron pairs had correlogram troughs consistent with convergent and divergent t-E inhibition of I cells and disinhibitory enhancement of drive. Four of 10 t-E neurons that responded to sequential stimulation of peripheral and central chemoreceptors triggered 25 cross-correlograms with offset features. The results support the hypothesis that multiple afferent systems dynamically tune inspiratory drive in part via coordinated t-E neurons. PMID:25343784
Ultra Small Integrated Optical Fiber Sensing System
Van Hoe, Bram; Lee, Graham; Bosman, Erwin; Missinne, Jeroen; Kalathimekkad, Sandeep; Maskery, Oliver; Webb, David J.; Sugden, Kate; Van Daele, Peter; Van Steenberge, Geert
2012-01-01
This paper introduces a revolutionary way to interrogate optical fiber sensors based on fiber Bragg gratings (FBGs) and to integrate the necessary driving optoelectronic components with the sensor elements. Low-cost optoelectronic chips are used to interrogate the optical fibers, creating a portable dynamic sensing system as an alternative for the traditionally bulky and expensive fiber sensor interrogation units. The possibility to embed these laser and detector chips is demonstrated resulting in an ultra thin flexible optoelectronic package of only 40 μm, provided with an integrated planar fiber pigtail. The result is a fully embedded flexible sensing system with a thickness of only 1 mm, based on a single Vertical-Cavity Surface-Emitting Laser (VCSEL), fiber sensor and photodetector chip. Temperature, strain and electrodynamic shaking tests have been performed on our system, not limited to static read-out measurements but dynamically reconstructing full spectral information datasets.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Moreno, Gilberto; Bennion, Kevin; King, Charles
Thermal management strategies for automotive power electronic systems have evolved over time to reduce system cost and to improve reliability and thermal performance. In this study, we characterized the power electronic thermal management systems of two electric-drive vehicles--the 2012 Nissan LEAF and 2014 Honda Accord Hybrid. Tests were conducted to measure the insulated-gate bipolar transistor-to-coolant thermal resistances for both steady-state and transient conditions at various coolant flow rates. Water-ethylene glycol at a temperature of 65 degrees C was used as the coolant for these experiments. Computational fluid dynamics and finite element analysis models of the vehicle's power electronics thermal managementmore » system were then created and validated using experimentally obtained results. Results indicate that the Accord module provides lower steady-state thermal resistance as compared with the LEAF module. However, the LEAF design may provide improved performance in transient conditions and may have cost benefits.« less
Influence of precipitating light elements on stable stratification below the core/mantle boundary
NASA Astrophysics Data System (ADS)
O'Rourke, J. G.; Stevenson, D. J.
2017-12-01
Stable stratification below the core/mantle boundary is often invoked to explain anomalously low seismic velocities in this region. Diffusion of light elements like oxygen or, more slowly, silicon could create a stabilizing chemical gradient in the outermost core. Heat flow less than that conducted along the adiabatic gradient may also produce thermal stratification. However, reconciling either origin with the apparent longevity (>3.45 billion years) of Earth's magnetic field remains difficult. Sub-isentropic heat flow would not drive a dynamo by thermal convection before the nucleation of the inner core, which likely occurred less than one billion years ago and did not instantly change the heat flow. Moreover, an oxygen-enriched layer below the core/mantle boundary—the source of thermal buoyancy—could establish double-diffusive convection where motion in the bulk fluid is suppressed below a slowly advancing interface. Here we present new models that explain both stable stratification and a long-lived dynamo by considering ongoing precipitation of magnesium oxide and/or silicon dioxide from the core. Lithophile elements may partition into iron alloys under extreme pressure and temperature during Earth's formation, especially after giant impacts. Modest core/mantle heat flow then drives compositional convection—regardless of thermal conductivity—since their solubility is strongly temperature-dependent. Our models begin with bulk abundances for the mantle and core determined by the redox conditions during accretion. We then track equilibration between the core and a primordial basal magma ocean followed by downward diffusion of light elements. Precipitation begins at a depth that is most sensitive to temperature and oxygen abundance and then creates feedbacks with the radial thermal and chemical profiles. Successful models feature a stable layer with low seismic velocity (which mandates multi-component evolution since a single light element typically increases seismic velocity) growing to its present-day size while allowing enough precipitation to drive compositional convection below. Crucially, this modeling offers unique constrains on Earth's accretion and the light element composition of the core compared to degenerate estimates derived from bulk density and seismic measurements.
Compound synchronization of four memristor chaotic oscillator systems and secure communication.
Sun, Junwei; Shen, Yi; Yin, Quan; Xu, Chengjie
2013-03-01
In this paper, a novel kind of compound synchronization among four chaotic systems is investigated, where the drive systems have been conceptually divided into two categories: scaling drive systems and base drive systems. Firstly, a sufficient condition is obtained to ensure compound synchronization among four memristor chaotic oscillator systems based on the adaptive technique. Secondly, a secure communication scheme via adaptive compound synchronization of four memristor chaotic oscillator systems is presented. The corresponding theoretical proofs and numerical simulations are given to demonstrate the validity and feasibility of the proposed control technique. The unpredictability of scaling drive systems can additionally enhance the security of communication. The transmitted signals can be split into several parts loaded in the drive systems to improve the reliability of communication.
Impacts of Launch Vehicle Fairing Size on Human Exploration Architectures
NASA Technical Reports Server (NTRS)
Jefferies, Sharon; Collins, Tim; Dwyer Cianciolo, Alicia; Polsgrove, Tara
2017-01-01
Human missions to Mars, particularly to the Martian surface, are grand endeavors that place extensive demands on ground infrastructure, launch capabilities, and mission systems. The interplay of capabilities and limitations among these areas can have significant impacts on the costs and ability to conduct Mars missions and campaigns. From a mission and campaign perspective, decisions that affect element designs, including those based on launch vehicle and ground considerations, can create effects that ripple through all phases of the mission and have significant impact on the overall campaign. These effects result in impacts to element designs and performance, launch and surface manifesting, and mission operations. In current Evolvable Mars Campaign concepts, the NASA Space Launch System (SLS) is the primary launch vehicle for delivering crew and payloads to cis-lunar space. SLS is currently developing an 8.4m diameter cargo fairing, with a planned upgrade to a 10m diameter fairing in the future. Fairing diameter is a driving factor that impacts many aspects of system design, vehicle performance, and operational concepts. It creates a ripple effect that influences all aspects of a Mars mission, including: element designs, grounds operations, launch vehicle design, payload packaging on the lander, launch vehicle adapter design to meet structural launch requirements, control and thermal protection during entry and descent at Mars, landing stability, and surface operations. Analyses have been performed in each of these areas to assess and, where possible, quantify the impacts of fairing diameter selection on all aspects of a Mars mission. Several potential impacts of launch fairing diameter selection are identified in each of these areas, along with changes to system designs that result. Solutions for addressing these impacts generally result in increased systems mass and propellant needs, which can further exacerbate packaging and flight challenges. This paper presents the results of the analyses performed, the potential changes to mission architectures and campaigns that result, and the general trends that are more broadly applicable to any element design or mission planning for human exploration.
National direct-drive program on OMEGA and the National Ignition Facility
NASA Astrophysics Data System (ADS)
Goncharov, V. N.; Regan, S. P.; Campbell, E. M.; Sangster, T. C.; Radha, P. B.; Myatt, J. F.; Froula, D. H.; Betti, R.; Boehly, T. R.; Delettrez, J. A.; Edgell, D. H.; Epstein, R.; Forrest, C. J.; Glebov, V. Yu; Harding, D. R.; Hu, S. X.; Igumenshchev, I. V.; Marshall, F. J.; McCrory, R. L.; Michel, D. T.; Seka, W.; Shvydky, A.; Stoeckl, C.; Theobald, W.; Gatu-Johnson, M.
2017-01-01
A major advantage of the laser direct-drive (DD) approach to ignition is the increased fraction of laser drive energy coupled to the hot spot and relaxed hot-spot requirements for the peak pressure and convergence ratios relative to the indirect-drive approach at equivalent laser energy. With the goal of a successful ignition demonstration using DD, the recently established national strategy has several elements and involves multiple national and international institutions. These elements include the experimental demonstration on OMEGA cryogenic implosions of hot-spot conditions relevant for ignition at MJ-scale energies available at the National Ignition Facility (NIF) and developing an understanding of laser-plasma interactions and laser coupling using DD experiments on the NIF. DD designs require reaching central stagnation pressures in excess of 100 Gbar. The current experiments on OMEGA have achieved inferred peak pressures of 56 Gbar (Regan et al 2016 Phys. Rev. Lett. 117 025001). Extensive analysis of the cryogenic target experiments and two- and three-dimensional simulations suggest that power balance, target offset, and target quality are the main limiting factors in target performance. In addition, cross-beam energy transfer (CBET) has been identified as the main mechanism reducing laser coupling. Reaching the goal of demonstrating hydrodynamic equivalence on OMEGA includes improving laser power balance, target position, and target quality at shot time. CBET must also be significantly reduced and several strategies have been identified to address this issue.
NASA Astrophysics Data System (ADS)
Hancock, L. O.
2013-12-01
G. Jones (1856) was first to suggest that the Earth might have its own ring, noting that an Earth ring in the ecliptic plane would account for the latitude dependence of the zodiacal light. Jones's proposal was not accepted: it is difficult to see why the ecliptic would accumulate mass within the Earth-Moon system. Very recently, however, this objection has been mitigated by the discovery of Saturn's Phoebe ring: evidently, the plane of a planetary moon's orbit has now been observed as the site of mass accumulation. An adjustment of just a few degrees from ecliptic to the plane of the lunar orbit gives Jones's proposal the boost of an existing Solar System analogue, mysterious though the analogue is. J. O'Keefe (1980) was first to suggest that an Earth ring system could drive climate: a ring in the equatorial plane, waxing and waning in optical depth, could drive the alternation of Ice Age and interglacial climates. This driver would account for the observation that the Ice Age climate was mainly a difference in winter only. Could Earth have a ring system with one or both elements? Even if light and unstable, it would be important to assess, as it could drive climate change. Dust assessments have not discovered a ring system, but they do not cover low orbits well, nor rule out very small particles stringently. Yet tiny particles can be optically important. There are many difficulties with this hypothesis: Why have ground-based observers never identified an equatorial ring, which after all should be the brightest element of a ring system? Why should a ring system be made of very small particles only? The material must be constantly falling to Earth - where is it? Finally, can we believe in the level of lunar geological activity needed to sustain an Earth ring system? This presentation addresses only one issue: Could ground-based observers have seen but misidentified an equatorial ring? To support consideration of that question, herewith a simple geometric exercise: a schema of ring effects on the southern sky: (i) extinction of extra-terrestrial light between celestial equator and horizon; (ii) brightening of extra-terrestrial light via light-through-dust effects near the southern horizon; and (iii) reflection of sunlight from celestial equator to horizon. These effects would be modulated by season (due to ring self-shadowing) and hour of the night (because of Earth's shadow). We suggest that the expected effects are not "missing" at all - similar effects are well known to observers but are taken to be fully accounted for by skyglow, airglow and light pollution, qualitatively similar phenomena that certainly exist. We conclude that ground-based observers' non-identification of an equatorial ring is not a counter-indicator of a ring's existence. As far as this consideration goes, the question of an Earth ring system is open.
Targets of opportunity : community based alcohol programs
DOT National Transportation Integrated Search
1988-04-01
Targets of Opportunity (TOP), were comprehensive community based programs addressing the drinking and driving concerns within a particular community. The program incorporated six elements: 1) General deterrence - public information,leducation and enf...
Simulated driving and brain imaging: combining behavior, brain activity, and virtual reality.
Carvalho, Kara N; Pearlson, Godfrey D; Astur, Robert S; Calhoun, Vince D
2006-01-01
Virtual reality in the form of simulated driving is a useful tool for studying the brain. Various clinical questions can be addressed, including both the role of alcohol as a modulator of brain function and regional brain activation related to elements of driving. We reviewed a study of the neural correlates of alcohol intoxication through the use of a simulated-driving paradigm and wished to demonstrate the utility of recording continuous-driving behavior through a new study using a programmable driving simulator developed at our center. Functional magnetic resonance imaging data was collected from subjects while operating a driving simulator. Independent component analysis (ICA) was used to analyze the data. Specific brain regions modulated by alcohol, and relationships between behavior, brain function, and alcohol blood levels were examined with aggregate behavioral measures. Fifteen driving epochs taken from two subjects while also recording continuously recorded driving variables were analyzed with ICA. Preliminary findings reveal that four independent components correlate with various aspects of behavior. An increase in braking while driving was found to increase activation in motor areas, while cerebellar areas showed signal increases during steering maintenance, yet signal decreases during steering changes. Additional components and significant findings are further outlined. In summary, continuous behavioral variables conjoined with ICA may offer new insight into the neural correlates of complex human behavior.
NASA Technical Reports Server (NTRS)
DeSmidt, Hans A.; Smith, Edward C.; Bill, Robert C.; Wang, Kon-Well
2013-01-01
This project develops comprehensive modeling and simulation tools for analysis of variable rotor speed helicopter propulsion system dynamics. The Comprehensive Variable-Speed Rotorcraft Propulsion Modeling (CVSRPM) tool developed in this research is used to investigate coupled rotor/engine/fuel control/gearbox/shaft/clutch/flight control system dynamic interactions for several variable rotor speed mission scenarios. In this investigation, a prototypical two-speed Dual-Clutch Transmission (DCT) is proposed and designed to achieve 50 percent rotor speed variation. The comprehensive modeling tool developed in this study is utilized to analyze the two-speed shift response of both a conventional single rotor helicopter and a tiltrotor drive system. In the tiltrotor system, both a Parallel Shift Control (PSC) strategy and a Sequential Shift Control (SSC) strategy for constant and variable forward speed mission profiles are analyzed. Under the PSC strategy, selecting clutch shift-rate results in a design tradeoff between transient engine surge margins and clutch frictional power dissipation. In the case of SSC, clutch power dissipation is drastically reduced in exchange for the necessity to disengage one engine at a time which requires a multi-DCT drive system topology. In addition to comprehensive simulations, several sections are dedicated to detailed analysis of driveline subsystem components under variable speed operation. In particular an aeroelastic simulation of a stiff in-plane rotor using nonlinear quasi-steady blade element theory was conducted to investigate variable speed rotor dynamics. It was found that 2/rev and 4/rev flap and lag vibrations were significant during resonance crossings with 4/rev lagwise loads being directly transferred into drive-system torque disturbances. To capture the clutch engagement dynamics, a nonlinear stick-slip clutch torque model is developed. Also, a transient gas-turbine engine model based on first principles mean-line compressor and turbine approximations is developed. Finally an analysis of high frequency gear dynamics including the effect of tooth mesh stiffness variation under variable speed operation is conducted including experimental validation. Through exploring the interactions between the various subsystems, this investigation provides important insights into the continuing development of variable-speed rotorcraft propulsion systems.
Distinguishing anticipation from causality: anticipatory bias in the estimation of information flow.
Hahs, Daniel W; Pethel, Shawn D
2011-09-16
We report that transfer entropy estimates obtained from low-resolution and/or small data sets show net information flow away from a purely anticipatory element whereas transfer entropy calculated using exact distributions show the flow towards it. This means that for real-world data sets anticipatory elements can appear to be strongly driving the network dynamics even when there is no possibility of such an influence. Furthermore, we show that in the low-resolution limit there is no statistic that can distinguish anticipatory elements from causal ones.
Patrick, John W.
2013-01-01
The pressure flow model of phloem transport envisaged by Münch (1930) has gained wide acceptance. Recently, however, the model has been questioned on structural and physiological grounds. For instance, sub-structures of sieve elements may reduce their hydraulic conductances to levels that impede flow rates of phloem sap and observed magnitudes of pressure gradients to drive flow along sieve tubes could be inadequate in tall trees. A variant of the Münch pressure flow model, the high-pressure manifold model of phloem transport introduced by Donald Fisher may serve to reconcile at least some of these questions. To this end, key predicted features of the high-pressure manifold model of phloem transport are evaluated against current knowledge of the physiology of phloem transport. These features include: (1) An absence of significant gradients in axial hydrostatic pressure in sieve elements from collection to release phloem accompanied by transport properties of sieve elements that underpin this outcome; (2) Symplasmic pathways of phloem unloading into sink organs impose a major constraint over bulk flow rates of resources translocated through the source-path-sink system; (3) Hydraulic conductances of plasmodesmata, linking sieve elements with surrounding phloem parenchyma cells, are sufficient to support and also regulate bulk flow rates exiting from sieve elements of release phloem. The review identifies strong circumstantial evidence that resource transport through the source-path-sink system is consistent with the high-pressure manifold model of phloem transport. The analysis then moves to exploring mechanisms that may link demand for resources, by cells of meristematic and expansion/storage sinks, with plasmodesmal conductances of release phloem. The review concludes with a brief discussion of how these mechanisms may offer novel opportunities to enhance crop biomass yields. PMID:23802003
Acoustic measurements on aerofoils moving in a circle at high speed
NASA Technical Reports Server (NTRS)
Wright, S. E.; Crosby, W.; Lee, D. L.
1982-01-01
Features of the test apparatus, research objectives and sample test results at the Stanford University rotor aerodynamics and noise facility are described. A steel frame equipped to receive lead shot for damping vibrations supports the drive shaft for rotor blade elements. Sleeve bearings are employed to assure quietness, and a variable speed ac motor produces the rotations. The test stand can be configured for horizontal or vertical orientation of the drive shaft. The entire assembly is housed in an acoustically sealed room. Rotation conditions for hover and large angles of attack can be studied, together with rotational and blade element noises. Research is possible on broad band, discrete frequency, and high speed noise, with measurements taken 3 m from the center of the rotor. Acoustic signatures from Mach 0.3-0.93 trials with a NACA 0012 airfoil are provided.
Decoupling control of steering and driving system for in-wheel-motor-drive electric vehicle
NASA Astrophysics Data System (ADS)
Zhang, Han; Zhao, Wanzhong
2018-02-01
To improve the maneuverability and stability of in-wheel-motor-drive electric vehicle, a control strategy based on nonlinear decoupling control method is proposed in this paper, realizing the coordinated control of the steering and driving system. At first, the nonlinear models of the in-wheel-motor-drive electric vehicle and its sub-system are constructed. Then the inverse system decoupling theory is applied to decompose the nonlinear system into several independent subsystems, which makes it possible to realize the coordinated control of each subsystem. Next, the μ-Synthesis theory is applied to eliminate the influence of model uncertainty, improving the stability, robustness and tracking performance of in-wheel-motor-drive electric vehicle. Simulation and experiment results and numerical analyses, based on the electric vehicle actuated by in-wheel-motors, prove that the proposed control method is effective to accomplish the decoupling control of the steering and driving system in both simulation and real practice.
NASA Astrophysics Data System (ADS)
Na, Yongyi
2017-03-01
The design of simple intelligent car, using AT89S52 single chip microcomputer as the car detection and control core; The metal sensor TL - Q5MC induction to iron, to detect the way to send feedback to the signal of single chip microcomputer, make SCM according to the scheduled work mode to control the car in the area according to the predetermined speed, and the operation mode of the microcontroller choose different also can control the car driving along s-shaped iron; Use A44E hall element to detect the car speeds; Adopts 1602 LCD display time of car driving, driving the car to stop, take turns to show the car driving time, distance, average speed and the speed of time. This design has simple structure and is easy to implement, but are highly intelligent, humane, to a certain extent reflects the intelligence.
A Novelty Design Of Minimization Of Electrical Losses In A Vector Controlled Induction Machine Drive
NASA Astrophysics Data System (ADS)
Aryza, Solly; Irwanto, M.; Lubis, Zulkarnain; Putera Utama Siahaan, Andysah; Rahim, Robbi; Furqan, Mhd.
2018-01-01
The induction motor has in the industry . More attention has been a focus to develop and design of induction motor drive. With the method of vector control novelty prove the efficiency of induction motor over their entire speed range. In this paper desirable to design a loss minimization controller which can improve the efficiency. Also, this research described Modeling of an induction motor with core loss included. Realization of methods vector control for an induction motor drive with loss element included. The case of the loss minimization condition. The procedure was successful to calculate the gains of a PI controller. Though the problem of obtaining a robust and sensorless induction motor drive is by no means completely solved, the results obtained as part of this work point in a promising direction.
A 32 x 32 capacitive micromachined ultrasonic transducer array manufactured in standard CMOS.
Lemmerhirt, David F; Cheng, Xiaoyang; White, Robert; Rich, Collin A; Zhang, Man; Fowlkes, J Brian; Kripfgans, Oliver D
2012-07-01
As ultrasound imagers become increasingly portable and lower cost, breakthroughs in transducer technology will be needed to provide high-resolution, real-time 3-D imaging while maintaining the affordability needed for portable systems. This paper presents a 32 x 32 ultrasound array prototype, manufactured using a CMUT-in-CMOS approach whereby ultrasonic transducer elements and readout circuits are integrated on a single chip using a standard integrated circuit manufacturing process in a commercial CMOS foundry. Only blanket wet-etch and sealing steps are added to complete the MEMS devices after the CMOS process. This process typically yields better than 99% working elements per array, with less than ±1.5 dB variation in receive sensitivity among the 1024 individually addressable elements. The CMUT pulseecho frequency response is typically centered at 2.1 MHz with a -6 dB fractional bandwidth of 60%, and elements are arranged on a 250 μm hexagonal grid (less than half-wavelength pitch). Multiplexers and CMOS buffers within the array are used to make on-chip routing manageable, reduce the number of physical output leads, and drive the transducer cable. The array has been interfaced to a commercial imager as well as a set of custom transmit and receive electronics, and volumetric images of nylon fishing line targets have been produced.
Generalized speed and cost rate in transitionless quantum driving
NASA Astrophysics Data System (ADS)
Xu, Zhen-Yu; You, Wen-Long; Dong, Yu-Li; Zhang, Chengjie; Yang, W. L.
2018-03-01
Transitionless quantum driving, also known as counterdiabatic driving, is a unique shortcut technique to adiabaticity, enabling a fast-forward evolution to the same target quantum states as those in the adiabatic case. However, as nothing is free, the fast evolution is obtained at the cost of stronger driving fields. Here, given the system initially gets prepared in equilibrium states, we construct relations between the dynamical evolution speed and the cost rate of transitionless quantum driving in two scenarios: one that preserves the transitionless evolution for a single energy eigenstate (individual driving), and the other that maintains all energy eigenstates evolving transitionlessly (collective driving). Remarkably, we find that individual driving may cost as much as collective driving, in contrast to the common belief that individual driving is more economical than collective driving in multilevel systems. We then present a potentially practical proposal to demonstrate the above phenomena in a three-level Landau-Zener model using the electronic spin system of a single nitrogen-vacancy center in diamond.
An efficient supersonic wind tunnel drive system for Mach 2.5 flows
NASA Technical Reports Server (NTRS)
Wolf, Stephen W. D.; Laub, James A.; King, Lyndell S.
1991-01-01
A novel efficient drive system has been developed which provides for the continuous operation of a pitot Mach 2.5 wind tunnel at compression ratios down to 0.625:1. The drive system does not require an overpressure to start, and no hysteresis has been observed. The general design of the proof-of-concept wind tunnel using the new drive system and its modifications are described.
NASA Astrophysics Data System (ADS)
Neves, M. C.; Searle, R. C.; Bott, M. H. P.
2003-04-01
We use two-dimensional elastic finite element analysis, supplemented by strength estimates, to investigate the driving mechanism of the Easter microplate. Modeled stresses are compared with the stress indicators compiled from earthquake focal mechanisms and structural observations. The objective is to constrain the tectonic forces that govern the Easter microplate rotation and to test the microplate driving hypothesis proposed by [1993]. We infer that the mantle basal drag cannot drive the microplate rotation but opposes it, and that the asthenospheric viscosity is no more than about 1 × 1018 Pa s. At most, the basal drag comprises 20% of the force resisting microplate rotation. The outward pull of the main plates can drive the rotation by shear drag applied along the northern and southern boundaries of the microplate. However, we propose an additional driving force which arises from the strong variation of the ridge resistance force along the east and west rifts, so that the main driving torques come from the pull of the major plates acting across the narrowing and slowing rifts. This requires the strength to increase substantially toward the rift tips due to thickening of the brittle lithosphere as the spreading rate slows.
Monotony of road environment and driver fatigue: a simulator study.
Thiffault, Pierre; Bergeron, Jacques
2003-05-01
Studies have shown that drowsiness and hypovigilance frequently occur during highway driving and that they may have serious implications in terms of accident causation. This paper focuses on the task induced factors that are involved in the development of these phenomena. A driving simulator study was conducted in order to evaluate the impact of the monotony of roadside visual stimulation using a steering wheel movement (SWM) analysis procedure. Fifty-six male subjects each drove during two different 40-min periods. In one case, roadside visual stimuli were essentially repetitive and monotonous, while in the other one, the environment contained disparate visual elements aiming to disrupt monotony without changing road geometry. Subject's driving performance was compared across these conditions in order to determine whether disruptions of monotony can have a positive effect and help alleviate driver fatigue. Results reveal an early time-on-task effect on driving performance for both driving periods and more frequent large SWM when driving in the more monotonous road environment, which implies greater fatigue and vigilance decrements. Implications in terms of environmental countermeasures for driver fatigue are discussed.
Propulsion for the lunar mission
NASA Technical Reports Server (NTRS)
Jones, Lee W.; Champion, Robert H., Jr.
1990-01-01
The paper describes the selection process utilized by NASA during the conduct of the 90-day study of the mission set that is known as the Space Exploration Initiative (SEI). It is directed specifically toward propulsion system definition and selection, with emphasis on the proposed Lunar Transfer Vehicle and the Lunar Exploration Vehicle. Results of trade studies show that selection cannot be readily made on the basis of engine performance alone, because the cost of launching hardware elements and the required propellant are very high. A decision must be made to use either life-cycle costs or annual program costs as the economic figure of merit, because they drive the selection in opposite directions.
Demeter, Sandor J
2016-12-21
Health care providers (HCP) and clinical scientists (CS) are generally most comfortable using evidence-based rational decision-making models. They become very frustrated when policymakers make decisions that, on the surface, seem irrational and unreasonable. However, such decisions usually make sense when analysed properly. The goal of this paper to provide a basic theoretical understanding of major policy models, to illustrate which models are most prevalent in publicly funded health care systems, and to propose a policy analysis framework to better understand the elements that drive policy decision-making. The proposed policy framework will also assist HCP and CS achieve greater success with their own proposals.
Stochastic memory: Memory enhancement due to noise
NASA Astrophysics Data System (ADS)
Stotland, Alexander; di Ventra, Massimiliano
2012-01-01
There are certain classes of resistors, capacitors, and inductors that, when subject to a periodic input of appropriate frequency, develop hysteresis loops in their characteristic response. Here we show that the hysteresis of such memory elements can also be induced by white noise of appropriate intensity even at very low frequencies of the external driving field. We illustrate this phenomenon using a physical model of memory resistor realized by TiO2 thin films sandwiched between metallic electrodes and discuss under which conditions this effect can be observed experimentally. We also discuss its implications on existing memory systems described in the literature and the role of colored noise.
Zhang, Feng; Zhang, Xin-shi
2004-01-01
Ecological construction and restoration for sustainable development are now a driving paradigm. It is increasingly recognized that ecological principles, especially landscape ecology theory, are not only necessary but also essential to maintain the long-term sustainability worldwide. Key landscape ecology principles-element, structure and process, dynamics, heterogeneity, hierarchies, connectivity, place and time were reviewed, and use Beijing area as a case study to illustrate how these principles might be applied to ecological construction and restoration, to eventually achieve sustainability. An example to more effectively incorporate the ecological principles in sustainable planning in China was presented.
Quick release latch for reactor scram
Johnson, Melvin L.; Shawver, Bruce M.
1976-01-01
A simple, reliable, and fast-acting means for releasing a control element and allowing it to be inserted rapidly into the core region of a nuclear reactor for scram purposes. A latch mechanism grips a coupling head on a nuclear control element to connect the control element to the control drive assembly. The latch mechanism is closed by tensioning a cable or rod with an actuator. The control element is released by de-energizing the actuator, providing fail-safe, rapid release of the control element to effect reactor shutdown. A sensing rod provides indication that the control element is properly positioned in the latch. Two embodiments are illustrated, one involving a collet-type latch mechanism, the other a pliers-type latch mechanism with the actuator located inside the reactor vessel.
Quick release latch for reactor scram
Johnson, M.L.; Shawver, B.M.
1975-09-16
A simple, reliable, and fast-acting means for releasing a control element and allowing it to be inserted rapidly into the core region of a nuclear reactor for scram purposes is described. A latch mechanism grips a coupling head on a nuclear control element to connect the control element to the control drive assembly. The latch mechanism is closed by tensioning a cable or rod with an actuator. The control element is released by de-energizing the actuator, providing fail-safe, rapid release of the control element to effect reactor shutdown. A sensing rod provides indication that the control element is properly positioned in the latch. Two embodiments are illustrated, one involving a collet- type latch mechanism, the other a pliers-type latch mechanism with the actuator located inside the reactor vessel. (auth)
Optically transduced MEMS gyro device
Nielson, Gregory N; Bogart, Gregory R; Langlois, Eric; Okandan, Murat
2014-05-20
A bulk micromachined vibratory gyro in which a proof mass has a bulk substrate thickness for a large mass and high inertial sensitivity. In embodiments, optical displacement transduction is with multi-layer sub-wavelength gratings for high sensitivity and low cross-talk with non-optical drive elements. In embodiments, the vibratory gyro includes a plurality of multi-layer sub-wavelength gratings and a plurality of drive electrodes to measure motion of the proof mass induced by drive forces and/or moments and induced by the Coriolis Effect when the gyro experiences a rotation. In embodiments, phase is varied across the plurality gratings and a multi-layer grating having the best performance is selected from the plurality.
Modelling of piezoelectric actuator dynamics for active structural control
NASA Technical Reports Server (NTRS)
Hagood, Nesbitt W.; Chung, Walter H.; Von Flotow, Andreas
1990-01-01
The paper models the effects of dynamic coupling between a structure and an electrical network through the piezoelectric effect. The coupled equations of motion of an arbitrary elastic structure with piezoelectric elements and passive electronics are derived. State space models are developed for three important cases: direct voltage driven electrodes, direct charge driven electrodes, and an indirect drive case where the piezoelectric electrodes are connected to an arbitrary electrical circuit with embedded voltage and current sources. The equations are applied to the case of a cantilevered beam with surface mounted piezoceramics and indirect voltage and current drive. The theoretical derivations are validated experimentally on an actively controlled cantilevered beam test article with indirect voltage drive.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Olszewski, Mitchell
The U.S. Department of Energy (DOE) announced in May 2011 a new cooperative research effort comprising DOE, the U.S. Council for Automotive Research (composed of automakers Ford Motor Company, General Motors Company, and Chrysler Group), Tesla Motors, and representatives of the electric utility and petroleum industries. Known as U.S. DRIVE (Driving Research and Innovation for Vehicle efficiency and Energy sustainability), it represents DOE's commitment to developing public-private partnerships to fund high risk-high reward research into advanced automotive technologies. The new partnership replaces and builds upon the partnership known as FreedomCAR (derived from 'Freedom' and 'Cooperative Automotive Research') that ran frommore » 2002 through 2010 and the Partnership for a New Generation of Vehicles initiative that ran from 1993 through 2001. The Oak Ridge National Laboratory's (ORNL's) Power Electronics and Electric Machines (PEEM) subprogram within the DOE Vehicle Technologies Program (VTP) provides support and guidance for many cutting-edge automotive technologies now under development. Research is focused on developing revolutionary new power electronics (PE), electric motor (EM), and traction drive system technologies that will leapfrog current on-the-road technologies. The research and development (R&D) is also aimed at achieving a greater understanding of and improvements in the way the various new components of tomorrow's automobiles will function as a unified system to improve fuel efficiency. In supporting the development of advanced vehicle propulsion systems, the PEEM subprogram has enabled the development of technologies that will significantly improve efficiency, costs, and fuel economy. The PEEM subprogram supports the efforts of the U.S. DRIVE partnership through a three phase approach intended to: (1) identify overall propulsion and vehicle related needs by analyzing programmatic goals and reviewing industry's recommendations and requirements and then develop the appropriate technical targets for systems, subsystems, and component R&D activities; (2) develop and validate individual subsystems and components, including EMs and PE; and (3) determine how well the components and subsystems work together in a vehicle environment or as a complete propulsion system and whether the efficiency and performance targets at the vehicle level have been achieved. The research performed under this subprogram will help remove technical and cost barriers to enable the development of technology for use in such advanced vehicles as hybrid electric vehicles (HEVs), plug-in HEVs (PHEVs), battery electric vehicles, and fuel-cell-powered automobiles that meet the goals of the VTP. A key element in making these advanced vehicles practical is providing an affordable electric traction drive system. This will require attaining weight, volume, efficiency, and cost targets for the PE and EM subsystems of the traction drive system. Areas of development include: (1) novel traction motor designs that result in increased power density and lower cost; (2) inverter technologies involving new topologies to achieve higher efficiency with the ability to accommodate higher temperature environments while achieving high reliability; (3) converter concepts that use methods of reducing the component count and integrating functionality to decrease size, weight, and cost; (4) new onboard battery charging concepts that result in decreased cost and size; (5) more effective thermal control through innovative packaging technologies; and (6) integrated motor-inverter traction drive system concepts. ORNL's PEEM research program conducts fundamental research, evaluates hardware, and assists in the technical direction of the VTP Advanced Power Electronics and Electric Motors (APEEM) program. In this role, ORNL serves on the U.S. DRIVE Electrical and Electronics Technical Team, evaluates proposals for DOE, and lends its technological expertise to the direction of projects and evaluation of developing technologies. ORNL also executes specific projects for DOE. DOE's continuing R&D into advanced vehicle technologies for transportation offers the possibility of reducing the nation's dependence on foreign oil and the negative economic impacts of crude oil price fluctuations. It also supports the Administration's goal of deploying 1 million PHEVs by 2015.« less
Development of testing and training simulator for CEDMCS in KSNP
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nam, C. H.; Park, C. Y.; Nam, J. I.
2006-07-01
This paper presents a newly developed testing and training simulator (TTS) for automatically diagnosing and tuning the Control Element Drive Mechanism Control System (CEDMCS). TTS includes a new automatic, diagnostic, method for logic control cards and a new tuning method for phase synchronous pulse cards. In Korea Standard Nuclear Power Plants (KSNP). reactor trips occasionally occur due to a damaged logic control card in CEDMCS. However, there is no pre-diagnostic tester available to detect a damaged card in CEDMCS before it causes a reactor trip. Even after the reactor trip occurs, it is difficult to find the damaged card. Tomore » find the damaged card. ICT is usually used. ICT is an automated, computer-controlled testing system with measurement capabilities for testing active and passive components, or clusters of components, on printed circuit boards (PCB) and/or assemblies. However, ICT cannot detect a time dependent fault correctly and requires removal of the waterproof mating to perform the test. Therefore, the additional procedure of re-coating the PCB card is required after the test. TTS for CEDMCS is designed based on real plant conditions, both electrically and mechanically. Therefore, the operator can operate the Control Element Drive Mechanism (CEDM), which is mounted on the closure head of the reactor vessel (RV) using the soft control panel in ITS, which duplicates the Main Control Board (MCB) in the Main Control Room (MCR). However, during the generation of electric power in a nuclear power plant, it is difficult to operate the CEDM so a CEDM and Control Element Assembly (CEA) mock-up facility was developed to simulate a real plant CEDM. ITS was used for diagnosing and tuning control logic cards in CEDMCS in the Ulchin Nuclear Power Plant No. 4 during the plant overhaul period. It exhibited good performance in detecting the damaged cards and tuning the phase synchronous pulse cards. In addition, TTS was useful in training the CEDMCS operator by supplying detail signal information from the logic cards. (authors)« less
Micro-Magnetic Suspension Motor Design for Miniature Optical Drive
NASA Astrophysics Data System (ADS)
Wang, Chien‑Chang; Yao, Yeong‑Der; Liu, Chien‑Sheng; Cheng, Lung‑Yu
2006-07-01
The main purpose of this study is to develop a low vibration micromotor applied in a miniature optical drive. To minimize the micromotor vibration, passive magnetic suspension technology has been used. The magnetic forces between the permanent magnets are estimated using the finite element method; the stable zone of operation of the motor developed was determined. A new micromotor with 62% of the radial vibration of the conventional micro-ball-bearing motor has been successfully developed. In addition, the new motor demonstrates lower friction torque loss.
NASA Astrophysics Data System (ADS)
Moulin-Frier, Clément; Verschure, Paul F. M. J.
2016-03-01
In the target paper [1], M.A. Arbib proposes a quite exhaustive review of the (often computational) models developed during the last decades that support his detailed scenario on language evolution (the Mirror System Hypothesis, MSH). The approach considers that language evolved from a mirror system for grasping already present in LCA-m (the last common ancestor of macaques and humans), to a simple imitation system for grasping present in LCA-c (the last common ancestor of chimpanzees and humans), to a complex imitation system for grasping that developed in the hominid line since that ancestor. MSH considers that this complex imitation system is a key evolutionary step for a language-ready brain, providing all the required elements for an open-ended gestural communication system. The transition from the gestural (bracchio-manual and visual) to the vocal (articulatory and auditory) domain is supposed to be a less important evolutionary step.
Advanced Data Acquisition Systems with Self-Healing Circuitry
NASA Technical Reports Server (NTRS)
Larson, William E.; Ihlefeld, Curtis M.; Medelius, Pedro J.; Delgado, H. (Technical Monitor)
2001-01-01
Kennedy Space Center's Spaceport Engineering & Technology Directorate has developed a data acquisition system that will help drive down the cost of ground launch operations. This system automates both the physical measurement set-up function as well as configuration management documentation. The key element of the system is a self-configuring, self-calibrating, signal-conditioning amplifier that automatically adapts to any sensor to which it is connected. This paper will describe the core technology behind this device and the automated data system in which it has been integrated. The paper will also describe the revolutionary enhancements that are planned for this innovative measurement technology. All measurement electronics devices contain circuitry that, if it fails or degrades, requires the unit to be replaced, adding to the cost of operations. Kennedy Space Center is now developing analog circuits that will be able to detect their own failure and dynamically reconfigure their circuitry to restore themselves to normal operation. This technology will have wide ranging application in all electronic devices used in space and ground systems.
Bacterial toxin-antitoxin systems: more than selfish entities?
Van Melderen, Laurence; Saavedra De Bast, Manuel
2009-03-01
Bacterial toxin-antitoxin (TA) systems are diverse and widespread in the prokaryotic kingdom. They are composed of closely linked genes encoding a stable toxin that can harm the host cell and its cognate labile antitoxin, which protects the host from the toxin's deleterious effect. TA systems are thought to invade bacterial genomes through horizontal gene transfer. Some TA systems might behave as selfish elements and favour their own maintenance at the expense of their host. As a consequence, they may contribute to the maintenance of plasmids or genomic islands, such as super-integrons, by post-segregational killing of the cell that loses these genes and so suffers the stable toxin's destructive effect. The function of the chromosomally encoded TA systems is less clear and still open to debate. This Review discusses current hypotheses regarding the biological roles of these evolutionarily successful small operons. We consider the various selective forces that could drive the maintenance of TA systems in bacterial genomes.
Bacterial Toxin–Antitoxin Systems: More Than Selfish Entities?
Van Melderen, Laurence; Saavedra De Bast, Manuel
2009-01-01
Bacterial toxin–antitoxin (TA) systems are diverse and widespread in the prokaryotic kingdom. They are composed of closely linked genes encoding a stable toxin that can harm the host cell and its cognate labile antitoxin, which protects the host from the toxin's deleterious effect. TA systems are thought to invade bacterial genomes through horizontal gene transfer. Some TA systems might behave as selfish elements and favour their own maintenance at the expense of their host. As a consequence, they may contribute to the maintenance of plasmids or genomic islands, such as super-integrons, by post-segregational killing of the cell that loses these genes and so suffers the stable toxin's destructive effect. The function of the chromosomally encoded TA systems is less clear and still open to debate. This Review discusses current hypotheses regarding the biological roles of these evolutionarily successful small operons. We consider the various selective forces that could drive the maintenance of TA systems in bacterial genomes. PMID:19325885
Drunk driving warning system (DDWS). Volume 1, System concept and description
DOT National Transportation Integrated Search
1983-11-01
The Drunk Driving Warning System (DDWS) is a vehicle-mounted device for testing driver impairment and activating alarms. The driver must pass a steering competency test in order to drive the car in a normal manner. The emergency flasher system operat...
Influence of the Mesh Geometry Evolution on Gearbox Dynamics during Its Maintenance
NASA Astrophysics Data System (ADS)
Dąbrowski, Z.; Dziurdź, J.; Klekot, G.
2017-12-01
Toothed gears constitute the necessary elements of power transmission systems. They are applied as stationary devices in drive systems of road vehicles, ships and crafts as well as airplanes and helicopters. One of the problems related to the toothed gears usage is the determination of their technical state or its evolutions. Assuming that the gear slippage velocity is attributed to vibrations and noises generated by cooperating toothed wheels, the application of a simple cooperation model of rolled wheels of skew teeth is proposed for the analysis of the mesh evolution influence on the gear dynamics. In addition, an example of utilising an ordinary coherence function for investigating evolutionary mesh changes related to the effects impossible to be described by means of the simple kinematic model is presented.
Infrared Detector System with Controlled Thermal Conductance
NASA Technical Reports Server (NTRS)
Cunningham, Thomas J. (Inventor)
2000-01-01
A thermal infrared detector system includes a heat sink, a support member, a connection support member connecting the support member to the heat sink and including a heater unit is reviewed. An infrared detector element is mounted on the support member and a temperature signal representative of the infrared energy contacting the support member can then be derived by comparing the temperature of the support member and the heat sink. The temperature signal from a support member and a temperature signal from the connection support member can then be used to drive a heater unit mounted on the connection support member to thereby control the thermal conductance of the support member. Thus, the thermal conductance can be controlled so that it can be actively increased or decreased as desired.
Guimarães, Raphael Mendonça; Meira, Karina Cardoso; Paz, Elisabete Pimenta Araújo; Dutra, Viviane Gomes Parreira; Campos, Carlos Eduardo Aguilera
2017-05-01
This article examines the evolution of health surveillance policies as actions, models and systems, as well as contributing to the debate about the constitution of the National Health Surveillance Policy (PNVS). The article discusses conceptual elements regarding the notion of health surveillance and its evolution in Brazil and a trajectory is provided in relation to the construction of care models, particularly after the creation of the Unified Health System (SUS). The possibility of using the framework of public policies based on evidence, and methods for analyzing health situations, such as spatial analysis and time series, are highlighted. To conclude, questions are raised regarding the effective creation of the PNVS, and the challenges that the federal executive faces in driving this process.
Investigation of a New Flux-Modulated Permanent Magnet Brushless Motor for EVs
Gu, Lingling; Luo, Yong; Han, Xuedong
2014-01-01
This paper presents a flux-modulated direct drive (FMDD) motor. The key is to integrate the magnetic gear with the PM motor while removing the gear inner-rotor. Hence, the proposed FMDD motor can achieve the low-speed high-torque output and high-speed compact design requirements as well as high-torque density with a simple structure. The output power equation is analytically derived. By using finite element analysis (FEA), the static characteristics of the proposed motor are obtained. Based on these characteristics, the system mathematical model can be established. Hence, the evaluation of system performances is conducted by computer simulation using the Matlab/Simulink. A prototype is designed and built for experimentation. Experimental results are given to verify the theoretical analysis and simulation. PMID:24883405
Focal plane transport assembly for the HEAO-B X-ray telescope
NASA Technical Reports Server (NTRS)
Brissette, R.; Allard, P. D.; Keller, F.; Strizhak, E.; Wester, E.
1979-01-01
The High Energy Astronomy Observatory - Mission B (HEAO-B), an earth orbiting X-ray telescope facility capable of locating and imaging celestial X-ray sources within one second of arc in the celestial sphere, is considered. The Focal Plane Transport Assembly (FPTA) is one of the basic structural elements of the three thousand pound HEAO-B experiment payload. The FPTA is a multifunctional assembly which supports seven imaging X-ray detectors circumferentially about a central shaft and accurately positions any particular one into the focus of a high resolution mirror assembly. A drive system, position sensor, rotary coupler, and detent alignment system, all an integral part of the rotatable portion which in turn is supported by main bearings to the stationary focal plane housing are described.
Investigation of a new flux-modulated permanent magnet brushless motor for EVs.
Fan, Ying; Gu, Lingling; Luo, Yong; Han, Xuedong; Cheng, Ming
2014-01-01
This paper presents a flux-modulated direct drive (FMDD) motor. The key is to integrate the magnetic gear with the PM motor while removing the gear inner-rotor. Hence, the proposed FMDD motor can achieve the low-speed high-torque output and high-speed compact design requirements as well as high-torque density with a simple structure. The output power equation is analytically derived. By using finite element analysis (FEA), the static characteristics of the proposed motor are obtained. Based on these characteristics, the system mathematical model can be established. Hence, the evaluation of system performances is conducted by computer simulation using the Matlab/Simulink. A prototype is designed and built for experimentation. Experimental results are given to verify the theoretical analysis and simulation.
Geramy, Allahyar; Mortezai, Omid; Esmaily, Masomeh; Darvishpour, Hojat
2015-04-01
Headgears are among the effective orthodontic appliances to achieve treatment goals. Unilateral molar distal movement is sometimes needed during an orthodontic treatment, which can be achieved by an asymmetric headgear. Different unilateral headgears have been introduced. The main goal of this study was to analyze the force system of unilateral expanded outer bow asymmetric headgears by the finite element method (FEM). Six 3D finite element models of a mesiodistal slice of the maxilla containing upper first molars, their periodontal ligaments (PDLs), cancellous bone, cortical bone, and a cervical headgear with expanded outer bow attached to maxillary first molars were designed in SolidWorks 2010 and meshed in ANSYS Workbench ver. 12.1. The models were the same except for the degree of outer bow expansion. The outer bow ends were loaded with 2 N force. The distal driving force and the net moment were evaluated. A decrease in the distalizing force in the normal side molar from 1.69 N to 1.37 N was shown by increasing the degree of unilateral expansion. At the same time, the force increased from 2.19 N to 2.49 N in the expanded side molar. A net moment increasing from 2.26 N.mm to 4.64 N.mm was also shown. Unilateral outer bow expansion can produce different distalizing forces in molars, which increase by increasing the expansion.
Ryu, Byoung Y.; Evans-Galea, Marguerite V.; Gray, John T.; Bodine, David M.; Persons, Derek A.
2008-01-01
Pathogenic activation of the LMO2 proto-oncogene by an oncoretroviral vector insertion in a clinical trial for X-linked severe combined immunodeficiency (X-SCID) has prompted safety concerns. We used an adeno-associated virus vector to achieve targeted insertion of a γ-retroviral long terminal repeat (LTR) driving a GFP expression cassette with flanking loxP sites in a human T-cell line at the precise location of vector integration in one of the patients with X-SCID. The LTR-GFP cassette was inserted into the first intron of the LMO2 gene, resulting in strong activation of LMO2. Cre-mediated cassette exchange was used to replace the original LTR-GFP cassette with one flanked by insulator elements leading to a several fold reduction in LMO2 expression. The LTR-GFP cassette was also replaced with a globin gene regulatory cassette that failed to activate the LMO2 gene in lymphoid cells. A γ-retroviral vector with 2 intact LTRs resulted in activation of the LMO2 gene when inserted into the first intron, but a self-inactivating lentiviral vector with an internal cellular promoter and flanking insulator elements did not activate the LMO2 gene. Thus, this system is useful for comparing the safety profiles of vector cassettes with various regulatory elements for their potential for proto-oncogene activation. PMID:17991809
NASA Technical Reports Server (NTRS)
1983-01-01
The space station mission requirements data base consists of 149 attached and free-flying missions each of which is documented by a set of three interrelated documents: (1) NASA LaRC Data Sheets - with three sheets comprising a set for each payload element described. These sheets contain user payload element data necessary to drive Space Station architectural options. (2) GDC-derived operations descriptions that supplement the LaRC payload element data in the operations areas such as further descriptions of crew involvement, EVA, etc. (3) Payload elements synthesis sheets used by GDC to provide requirements traceability to data sources and to provide a narrative describing the basis for formulating the payload element requirements.
32 CFR 634.46 - Point system procedures.
Code of Federal Regulations, 2013 CFR
2013-07-01
... CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Driving Records and the Traffic Point System... traffic points or the suspension or revocation of driving privileges on the person's driving record... or driving privileges suspended or revoked when the report of action taken indicates that neither...
32 CFR 634.46 - Point system procedures.
Code of Federal Regulations, 2012 CFR
2012-07-01
... CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Driving Records and the Traffic Point System... traffic points or the suspension or revocation of driving privileges on the person's driving record... or driving privileges suspended or revoked when the report of action taken indicates that neither...
32 CFR 634.46 - Point system procedures.
Code of Federal Regulations, 2014 CFR
2014-07-01
... CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Driving Records and the Traffic Point System... traffic points or the suspension or revocation of driving privileges on the person's driving record... or driving privileges suspended or revoked when the report of action taken indicates that neither...
The application of multilayer elastic beam in MEMS safe and arming system
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li, Guozhong, E-mail: liguozhong-bit@bit.edu.cn; Shi, Gengchen; Sui, Li
In this paper, a new approach for a multilayer elastic beam to provide a driving force and driving distance for a MEMS safe and arming system is presented. In particular this is applied where a monolayer elastic beam cannot provide adequate driving force and driving distance at the same time in limited space. Compared with thicker elastic beams, the bilayer elastic beam can provide twice the driving force of a monolayer beam to guarantee the MEMS safe and arming systems work reliably without decreasing the driving distance. In this paper, the theoretical analysis, numerical simulation and experimental verification of themore » multilayer elastic beam is presented. The numerical simulation and experimental results show that the bilayer elastic provides 1.8–2 times the driving force of a monolayer, and a method that improves driving force without reducing the driving distance.« less
Improving driving advice provided to cardiology patients on discharge.
Vusirikala, Amoolya; Backhouse, Mark; Schimansky, Sarah
2018-01-01
Certain cardiac conditions can limit patients' ability to drive. It remains the doctors' responsibility to advise patients of any driving restrictions and is particularly important after certain diagnoses or procedures. We identified that the quality of documented advice was variable and frequently no written driving advice was recorded on discharge. It was apparent that there was a lack of awareness and knowledge of the current Driving and Vehicle Licensing Agency (DVLA) guidance among junior doctors. We therefore designed a quality improvement project using Plan-Do-Study-Act (PDSA) methodology to improve the provision of driving advice on discharge from a cardiology ward by focusing on staff education. After collecting baseline data, we created a template with cardiology-specific DVLA advice. During the second PDSA cycle, we improved the electronic template and also introduced a hard copy on the ward. During the third PDSA cycle, we incorporated information on DVLA guidance in the specialty induction session. We also evaluated junior doctors' confidence of providing driving advice before and after this intervention. Baseline measurements showed that 10% (9/92) of all discharge summaries included driving advice. This improved to 49% (34/69) after the third PDSA cycle. Importantly, after receiving information on driving advice in the induction, junior doctors felt more confident in providing driving advice to cardiology patients on discharge. In conclusion, the provision of driving advice on discharge is an important element of patient safety. However, clinicians' knowledge and awareness of current DVLA guidance is often limited. We demonstrated a significant increase in the provision of driving advice by introducing a standardised template.
Improving driving advice provided to cardiology patients on discharge
Vusirikala, Amoolya; Backhouse, Mark; Schimansky, Sarah
2018-01-01
Certain cardiac conditions can limit patients’ ability to drive. It remains the doctors' responsibility to advise patients of any driving restrictions and is particularly important after certain diagnoses or procedures. We identified that the quality of documented advice was variable and frequently no written driving advice was recorded on discharge. It was apparent that there was a lack of awareness and knowledge of the current Driving and Vehicle Licensing Agency (DVLA) guidance among junior doctors. We therefore designed a quality improvement project using Plan–Do–Study–Act (PDSA) methodology to improve the provision of driving advice on discharge from a cardiology ward by focusing on staff education. After collecting baseline data, we created a template with cardiology-specific DVLA advice. During the second PDSA cycle, we improved the electronic template and also introduced a hard copy on the ward. During the third PDSA cycle, we incorporated information on DVLA guidance in the specialty induction session. We also evaluated junior doctors’ confidence of providing driving advice before and after this intervention. Baseline measurements showed that 10% (9/92) of all discharge summaries included driving advice. This improved to 49% (34/69) after the third PDSA cycle. Importantly, after receiving information on driving advice in the induction, junior doctors felt more confident in providing driving advice to cardiology patients on discharge. In conclusion, the provision of driving advice on discharge is an important element of patient safety. However, clinicians’ knowledge and awareness of current DVLA guidance is often limited. We demonstrated a significant increase in the provision of driving advice by introducing a standardised template. PMID:29610769
A Case Study of Dynamic Response Analysis and Safety Assessment for a Suspended Monorail System.
Bao, Yulong; Li, Yongle; Ding, Jiajie
2016-11-10
A suspended monorail transit system is a category of urban rail transit, which is effective in alleviating traffic pressure and injury prevention. Meanwhile, with the advantages of low cost and short construction time, suspended monorail transit systems show vast potential for future development. However, the suspended monorail has not been systematically studied in China, and there is a lack of relevant knowledge and analytical methods. To ensure the health and reliability of a suspended monorail transit system, the driving safety of vehicles and structure dynamic behaviors when vehicles are running on the bridge should be analyzed and evaluated. Based on the method of vehicle-bridge coupling vibration theory, the finite element method (FEM) software ANSYS and multi-body dynamics software SIMPACK are adopted respectively to establish the finite element model for bridge and the multi-body vehicle. A co-simulation method is employed to investigate the vehicle-bridge coupling vibration for the transit system. The traffic operation factors, including train formation, track irregularity and tire stiffness, are incorporated into the models separately to analyze the bridge and vehicle responses. The results show that the coupling of dynamic effects of the suspended monorail system between vehicle and bridge are significant in the case studied, and it is strongly suggested to take necessary measures for vibration suppression. The simulation of track irregularity is a critical factor for its vibration safety, and the track irregularity of A-level road roughness negatively influences the system vibration safety.
A Case Study of Dynamic Response Analysis and Safety Assessment for a Suspended Monorail System
Bao, Yulong; Li, Yongle; Ding, Jiajie
2016-01-01
A suspended monorail transit system is a category of urban rail transit, which is effective in alleviating traffic pressure and injury prevention. Meanwhile, with the advantages of low cost and short construction time, suspended monorail transit systems show vast potential for future development. However, the suspended monorail has not been systematically studied in China, and there is a lack of relevant knowledge and analytical methods. To ensure the health and reliability of a suspended monorail transit system, the driving safety of vehicles and structure dynamic behaviors when vehicles are running on the bridge should be analyzed and evaluated. Based on the method of vehicle-bridge coupling vibration theory, the finite element method (FEM) software ANSYS and multi-body dynamics software SIMPACK are adopted respectively to establish the finite element model for bridge and the multi-body vehicle. A co-simulation method is employed to investigate the vehicle-bridge coupling vibration for the transit system. The traffic operation factors, including train formation, track irregularity and tire stiffness, are incorporated into the models separately to analyze the bridge and vehicle responses. The results show that the coupling of dynamic effects of the suspended monorail system between vehicle and bridge are significant in the case studied, and it is strongly suggested to take necessary measures for vibration suppression. The simulation of track irregularity is a critical factor for its vibration safety, and the track irregularity of A-level road roughness negatively influences the system vibration safety. PMID:27834923
Survey of the present state of the art of piezoelectric linear motors
Hemsel; Wallaschek
2000-03-01
Piezoelectric ultrasonic motors have been investigated for several years and have already found their first practical applications. Their key feature is that they are able to produce a high thrust force related to their volume. Beside rotary drives like the travelling wave motor, linear drives have also been developed, but only a few are presently commercially available. In the present paper, we first describe the state of the art of linear piezoelectric motors. The motors are characterized with respect to their no-load velocity, maximum thrust force, efficiency and other technical properties. In the second part, we present a new motor, which is judged to be capable of surpassing the characteristics of other piezoelectric motors because of its unique design which allows the piezoelectric drive elements to be pre-stressed in the direction of their polarization. The piezoelectric elements convert energy using the longitudinal d33 effect which allows an improved reliability, large vibration amplitudes and excellent piezoelectric coupling. Energy loss by vibration damping is minimized, and the efficiency can be improved significantly. Experimental results show that the motor characteristics can be optimized for a particular task by choosing the appropriate operating parameters such as exciting voltage, exciting frequency and normal force.
Habib, Komal; Parajuly, Keshav; Wenzel, Henrik
2015-10-20
Recovery of resources, in particular, metals, from waste flows is widely seen as a prioritized option to reduce their potential supply constraints in the future. The current waste electrical and electronic equipment (WEEE) treatment system is more focused on bulk metals, where the recycling rate of specialty metals, such as rare earths, is negligible compared to their increasing use in modern products, such as electronics. This study investigates the challenges in recovering these resources in the existing WEEE treatment system. It is illustrated by following the material flows of resources in a conventional WEEE treatment plant in Denmark. Computer hard disk drives (HDDs) containing neodymium-iron-boron (NdFeB) magnets were selected as the case product for this experiment. The resulting output fractions were tracked until their final treatment in order to estimate the recovery potential of rare earth elements (REEs) and other resources contained in HDDs. The results further show that out of the 244 kg of HDDs treated, 212 kg comprising mainly of aluminum and steel can be finally recovered from the metallurgic process. The results further demonstrate the complete loss of REEs in the existing shredding-based WEEE treatment processes. Dismantling and separate processing of NdFeB magnets from their end-use products can be a more preferred option over shredding. However, it remains a technological and logistic challenge for the existing system.
Verberne, Frank M F; Ham, Jaap; Midden, Cees J H
2012-10-01
We examine whether trust in smart systems is generated analogously to trust in humans and whether the automation level of smart systems affects trustworthiness and acceptability of those systems. Trust is an important factor when considering acceptability of automation technology. As shared goals lead to social trust, and intelligent machines tend to be treated like humans, the authors expected that shared driving goals would also lead to increased trustworthiness and acceptability of adaptive cruise control (ACC) systems. In an experiment, participants (N = 57) were presented with descriptions of three ACCs with different automation levels that were described as systems that either shared their driving goals or did not. Trustworthiness and acceptability of all the ACCs were measured. ACCs sharing the driving goals of the user were more trustworthy and acceptable than were ACCs not sharing the driving goals of the user. Furthermore, ACCs that took over driving tasks while providing information were more trustworthy and acceptable than were ACCs that took over driving tasks without providing information. Trustworthiness mediated the effects of both driving goals and automation level on acceptability of ACCs. As when trusting other humans, trusting smart systems depends on those systems sharing the user's goals. Furthermore, based on their description, smart systems that take over tasks are judged more trustworthy and acceptable when they also provide information. For optimal acceptability of smart systems, goals of the user should be shared by the smart systems, and smart systems should provide information to their user.
NASA Astrophysics Data System (ADS)
Kiso, Atsushi; Murakami, Hiroki; Seki, Hirokazu
This paper describes a novel obstacle avoidance control scheme of electric powered wheelchairs for realizing the safe driving in various environments. The “electric powered wheelchair” which generates the driving force by electric motors is expected to be widely used as a mobility support system for elderly people and disabled people; however, the driving performance must be further improved because the number of driving accidents caused by elderly operator's narrow sight and joystick operation errors is increasing. This paper proposes a novel obstacle avoidance control scheme based on fuzzy algorithm to prevent driving accidents. The proposed control system determines the driving direction by fuzzy algorithm based on the information of the joystick operation and distance to obstacles measured by ultrasonic sensors. Fuzzy rules to determine the driving direction are designed surely to avoid passers-by and walls considering the human's intent and driving environments. Some driving experiments on the practical situations show the effectiveness of the proposed control system.
Synthetically engineered Medea gene drive system in the worldwide crop pest Drosophila suzukii
Buchman, Anna; Marshall, John M.; Ostrovski, Dennis; Yang, Ting; Akbari, Omar S.
2018-01-01
Synthetic gene drive systems possess enormous potential to replace, alter, or suppress wild populations of significant disease vectors and crop pests; however, their utility in diverse populations remains to be demonstrated. Here, we report the creation of a synthetic Medea gene drive system in a major worldwide crop pest, Drosophila suzukii. We demonstrate that this drive system, based on an engineered maternal “toxin” coupled with a linked embryonic “antidote,” is capable of biasing Mendelian inheritance rates with up to 100% efficiency. However, we find that drive resistance, resulting from naturally occurring genetic variation and associated fitness costs, can be selected for and hinder the spread of such a drive. Despite this, our results suggest that this gene drive could maintain itself at high frequencies in a wild population and spread to fixation if either its fitness costs or toxin resistance were reduced, providing a clear path forward for developing future such systems in this pest. PMID:29666236
NASA Astrophysics Data System (ADS)
Bai, Zheng Feng; Zhao, Ji Jun; Chen, Jun; Zhao, Yang
2018-03-01
In the dynamic analysis of satellite antenna dual-axis driving mechanism, it is usually assumed that the joints are ideal or perfect without clearances. However, in reality, clearances in joints are unavoidable due to assemblage, manufacturing errors and wear. When clearance is introduced to the mechanism, it will lead to poor dynamic performances and undesirable vibrations due to impact forces in clearance joint. In this paper, a design optimization method is presented to reduce the undesirable vibrations of satellite antenna considering clearance joints in dual-axis driving mechanism. The contact force model in clearance joint is established using a nonlinear spring-damper model and the friction effect is considered using a modified Coulomb friction model. Firstly, the effects of clearances on dynamic responses of satellite antenna are investigated. Then the optimization method for dynamic design of the dual-axis driving mechanism with clearance is presented. The objective of the optimization is to minimize the maximum absolute vibration peak of antenna acceleration by reducing the impact forces in clearance joint. The main consideration here is to optimize the contact parameters of the joint elements. The contact stiffness coefficient, damping coefficient and the dynamic friction coefficient for clearance joint elements are taken as the optimization variables. A Generalized Reduced Gradient (GRG) algorithm is used to solve this highly nonlinear optimization problem for dual-axis driving mechanism with clearance joints. The results show that the acceleration peaks of satellite antenna and contact forces in clearance joints are reduced obviously after design optimization, which contributes to a better performance of the satellite antenna. Also, the application and limitation of the proposed optimization method are discussed.
Modeling and Positioning of a PZT Precision Drive System.
Liu, Che; Guo, Yanling
2017-11-08
The fact that piezoelectric ceramic transducer (PZT) precision drive systems in 3D printing are faced with nonlinear problems with respect to positioning, such as hysteresis and creep, has had an extremely negative impact on the precision of laser focusing systems. To eliminate the impact of PZT nonlinearity during precision drive movement, mathematical modeling and theoretical analyses of each module comprising the system were carried out in this study, a micro-displacement measurement circuit based on Position Sensitive Detector (PSD) is constructed, followed by the establishment of system closed-loop control and creep control models. An XL-80 laser interferometer (Renishaw, Wotton-under-Edge, UK) was used to measure the performance of the precision drive system, showing that system modeling and control algorithms were correct, with the requirements for precision positioning of the drive system satisfied.
Modeling and Positioning of a PZT Precision Drive System
Liu, Che; Guo, Yanling
2017-01-01
The fact that piezoelectric ceramic transducer (PZT) precision drive systems in 3D printing are faced with nonlinear problems with respect to positioning, such as hysteresis and creep, has had an extremely negative impact on the precision of laser focusing systems. To eliminate the impact of PZT nonlinearity during precision drive movement, mathematical modeling and theoretical analyses of each module comprising the system were carried out in this study, a micro-displacement measurement circuit based on Position Sensitive Detector (PSD) is constructed, followed by the establishment of system closed-loop control and creep control models. An XL-80 laser interferometer (Renishaw, Wotton-under-Edge, UK) was used to measure the performance of the precision drive system, showing that system modeling and control algorithms were correct, with the requirements for precision positioning of the drive system satisfied. PMID:29117140
NASA Astrophysics Data System (ADS)
Wang, Song-Bai; Chen, Ye-Hong; Wu, Qi-Cheng; Shi, Zhi-Cheng; Huang, Bi-Hua; Song, Jie; Xia, Yan
2018-07-01
A scheme is proposed to implement quantum state engineering (QSE) in a four-state system via counterdiabatic driving. In the scheme, single- and multi-mode driving methods are used respectively to drive the system to a target state at a predefined time. It is found that a fast QSE can be realized by utilizing simply designed pulses. In addition, a beneficial discussion on the energy consumption between the single- and multi-mode driving protocols shows that the multi-mode driving method seems to have a wider range of applications than the single-mode driving method with respect to different parameters. Finally, the scheme is also helpful for implementing the generalization QSE in high-dimensional systems via the concept of a dressed state. Therefore, the scheme can be implemented with the present experimental technology, which is useful in quantum information processing.
Haldane’s Rule Is Linked to Extraordinary Sex Ratios and Sperm Length in Stalk-Eyed Flies
Wilkinson, Gerald S.; Christianson, Sarah J.; Brand, Cara L.; Ru, George; Shell, Wyatt
2014-01-01
We use three allopatric populations of the stalk-eyed fly Teleopsis dalmanni from Southeast Asia to test two predictions made by the sex chromosome drive hypothesis for Haldane’s rule. The first is that modifiers that suppress or enhance drive should evolve rapidly and independently in isolated populations. The second is that drive loci or modifiers should also cause sterility in hybrid males. We tested these predictions by assaying the fertility of 2066 males derived from backcross experiments involving two pairs of populations and found that the proportion of mated males that fail to produce any offspring ranged from 38 to 60% among crosses with some males producing strongly female-biased or male-biased sex ratios. After genotyping each male at 25–28 genetic markers we found quantitative trait loci (QTL) that jointly influence male sterility, sperm length, and biased progeny sex ratios in each pair of populations, but almost no shared QTL between population crosses. We also discovered that the extant XSR chromosome has no effect on sex ratio or sterility in these backcross males. Whether shared QTL are caused by linkage or pleiotropy requires additional study. Nevertheless, these results indicate the presence of a “cryptic” drive system that is currently masked by suppressing elements that are associated with sterility and sperm length within but not between populations and, therefore, must have evolved since the populations became isolated, i.e., in <100,000 years. We discuss how genes that influence sperm length may contribute to hybrid sterility. PMID:25164880
NASA Astrophysics Data System (ADS)
Li, Yutong; Hansen, Andreas; Karl Hedrick, J.; Zhang, Junzhi
2017-12-01
Active control of electric powertrains is challenging, due to the fact that backlash and structural flexibility in transmission components can cause severe performance degradation or even instability of the control system. Furthermore, high impact forces in transmissions reduce driving comfort and possibly lead to damage of the mechanical elements in contact. In this paper, a nonlinear electric powertrain is modelled as a piecewise affine (PWA) system. The novel receding horizon sliding control (RHSC) idea is extended to constrained PWA systems and utilised to systematically address the active control problem for electric powertrains. Simulations are conducted in Matlab/Simulink in conjunction with the high fidelity Carsim software. RHSC shows superior jerk suppression and target wheel speed tracking performance as well as reduced computational cost over classical model predictive control (MPC). This indicates the newly proposed RHSC is an effective method to address the active control problem for electric powertrains.
Bassett, Danielle S; Sporns, Olaf
2017-01-01
Despite substantial recent progress, our understanding of the principles and mechanisms underlying complex brain function and cognition remains incomplete. Network neuroscience proposes to tackle these enduring challenges. Approaching brain structure and function from an explicitly integrative perspective, network neuroscience pursues new ways to map, record, analyze and model the elements and interactions of neurobiological systems. Two parallel trends drive the approach: the availability of new empirical tools to create comprehensive maps and record dynamic patterns among molecules, neurons, brain areas and social systems; and the theoretical framework and computational tools of modern network science. The convergence of empirical and computational advances opens new frontiers of scientific inquiry, including network dynamics, manipulation and control of brain networks, and integration of network processes across spatiotemporal domains. We review emerging trends in network neuroscience and attempt to chart a path toward a better understanding of the brain as a multiscale networked system. PMID:28230844
System to continuously produce carbon fiber via microwave assisted plasma processing
White, Terry L [Knoxville, TN; Paulauskas, Felix L [Knoxville, TN; Bigelow, Timothy S [Knoxville, TN
2010-11-02
A system to continuously produce fully carbonized or graphitized carbon fibers using microwave-assisted plasma (MAP) processing comprises an elongated chamber in which a microwave plasma is excited in a selected gas atmosphere. Fiber is drawn continuously through the chamber, entering and exiting through openings designed to minimize in-leakage of air. There is a gradient of microwave power within the chamber with generally higher power near where the fiber exits and lower power near where the fiber enters. Polyacrylonitrile (PAN), pitch, or any other suitable organic/polymeric precursor fibers can be used as a feedstock for the inventive system. Oxidized or partially oxidized PAN or pitch or other polymeric fiber precursors are run continuously through a MAP reactor in an inert, non-oxidizing atmosphere to heat the fibers, drive off the unwanted elements such as oxygen, nitrogen, and hydrogen, and produce carbon or graphite fibers faster than conventionally produced carbon fibers.
Boriani, Elena; Esposito, Roberto; Frazzoli, Chiara; Fantke, Peter; Hald, Tine; Rüegg, Simon R.
2017-01-01
Health intervention systems are complex and subject to multiple variables in different phases of implementation. This constitutes a concrete challenge for the application of translational science in real life. Complex systems as health-oriented interventions call for interdisciplinary approaches with carefully defined system boundaries. Exploring individual components of such systems from different viewpoints gives a wide overview and helps to understand the elements and the relationships that drive actions and consequences within the system. In this study, we present an application and assessment of a framework with focus on systems and system boundaries of interdisciplinary projects. As an example on how to apply our framework, we analyzed ALERT [an integrated sensors and biosensors’ system (BEST) aimed at monitoring the quality, health, and traceability of the chain of the bovine milk], a multidisciplinary and interdisciplinary project based on the application of measurable biomarkers at strategic points of the milk chain for improved food security (including safety), human, and ecosystem health (1). In fact, the European food safety framework calls for science-based support to the primary producers’ mandate for legal, scientific, and ethical responsibility in food supply. Because of its multidisciplinary and interdisciplinary approach involving human, animal, and ecosystem health, ALERT can be considered as a One Health project. Within the ALERT context, we identified the need to take into account the main actors, interactions, and relationships of stakeholders to depict a simplified skeleton of the system. The framework can provide elements to highlight how and where to improve the project development when project evaluations are required. PMID:28804707
Boriani, Elena; Esposito, Roberto; Frazzoli, Chiara; Fantke, Peter; Hald, Tine; Rüegg, Simon R
2017-01-01
Health intervention systems are complex and subject to multiple variables in different phases of implementation. This constitutes a concrete challenge for the application of translational science in real life. Complex systems as health-oriented interventions call for interdisciplinary approaches with carefully defined system boundaries. Exploring individual components of such systems from different viewpoints gives a wide overview and helps to understand the elements and the relationships that drive actions and consequences within the system. In this study, we present an application and assessment of a framework with focus on systems and system boundaries of interdisciplinary projects. As an example on how to apply our framework, we analyzed ALERT [an integrated sensors and biosensors' system (BEST) aimed at monitoring the quality, health, and traceability of the chain of the bovine milk], a multidisciplinary and interdisciplinary project based on the application of measurable biomarkers at strategic points of the milk chain for improved food security (including safety), human, and ecosystem health (1). In fact, the European food safety framework calls for science-based support to the primary producers' mandate for legal, scientific, and ethical responsibility in food supply. Because of its multidisciplinary and interdisciplinary approach involving human, animal, and ecosystem health, ALERT can be considered as a One Health project. Within the ALERT context, we identified the need to take into account the main actors, interactions, and relationships of stakeholders to depict a simplified skeleton of the system. The framework can provide elements to highlight how and where to improve the project development when project evaluations are required.
Structure and mechanical design for a large-aperture telescope
NASA Astrophysics Data System (ADS)
Tan, Yufeng; Wang, Jihong; Ren, Ge; Ren, Xiaoli; Xie, Zongliang; Li, Dong
2018-02-01
For a better understanding and forecasting of the universe, the high resolution observations are needed. The largeaperture telescope is an integrated success with a combination of material, mechanics, optics and electronics. The telescope is a classic Cassegrain configuration with open structure, alt-azimuth mount, and retractable dome. The instrumentation has a rotating mass of approximately 52 tons and stands over 9 m tall. The 3-m aperture primary mirror is a honeycomb lightweighted mirror with fused silica material and active cooling. The paper will address preliminary design and development of the telescope mount structure, axes drive system, encoder mount and primary mirror system. The structure must have the best performance of stiffness and stability to demand an acceptable image quality. As the largest optical element of the telescope, primary mirror must be well controlled and protected both during operational and non-operational periods. An active cooling system of primary mirror is provided by a flushing subsystem at the front side and sucking subsystem on the central hole to keep the temperature of the facesheet close to that of ambient air. A two-layer mirror cover mounted on the elevation ring is proposed to protect the optical elements and inner beam tube from dust, dirt and debris. Furthermore, the latest plans for future upgrades will be also described.
High reliability linear drive device for artificial hearts
NASA Astrophysics Data System (ADS)
Ji, Jinghua; Zhao, Wenxiang; Liu, Guohai; Shen, Yue; Wang, Fangqun
2012-04-01
In this paper, a new high reliability linear drive device, termed as stator-permanent-magnet tubular oscillating actuator (SPM-TOA), is proposed for artificial hearts (AHs). The key is to incorporate the concept of two independent phases into this linear AH device, hence achieving high reliability operation. The fault-tolerant teeth are employed to provide the desired decoupling phases in magnetic circuit. Also, as the magnets and the coils are located in the stator, the proposed SPM-TOA takes the definite advantages of robust mover and direct-drive capability. By using the time-stepping finite element method, the electromagnetic characteristics of the proposed SPM-TOA are analyzed, including magnetic field distributions, flux linkages, back- electromotive forces (back-EMFs) self- and mutual inductances, as well as cogging and thrust forces. The results confirm that the proposed SPM-TOA meets the dimension, weight, and force requirements of the AH drive device.
Shope, J T
2006-06-01
This paper presents an organized, comprehensive view of the factors known to influence young drivers' behavior and how those factors might inform interventions to reduce crashes. This effort was done from the perspective of a public health professional, with a background in health behavior and health education, interested in preventing injury and death among young people from motor vehicle crashes. The author's own studies, selected relevant literature, observation, and experience were considered and organized. A framework of six categories of influences on youthful driving behavior was developed, including the following elements: driving ability, developmental factors, personality factors, demographics, the perceived environment, and the driving environment. It is apparent that a complex set of many different factors influences young drivers' behavior. To reduce crashes, comprehensive, multilevel interventions are needed that target those factors in the framework that are amenable to change.
Shope, J T
2006-01-01
This paper presents an organized, comprehensive view of the factors known to influence young drivers' behavior and how those factors might inform interventions to reduce crashes. This effort was done from the perspective of a public health professional, with a background in health behavior and health education, interested in preventing injury and death among young people from motor vehicle crashes. The author's own studies, selected relevant literature, observation, and experience were considered and organized. A framework of six categories of influences on youthful driving behavior was developed, including the following elements: driving ability, developmental factors, personality factors, demographics, the perceived environment, and the driving environment. It is apparent that a complex set of many different factors influences young drivers' behavior. To reduce crashes, comprehensive, multilevel interventions are needed that target those factors in the framework that are amenable to change. PMID:16788115
Improved motors for utility applications: Volume 6, Squirrel-cage rotor analysis: Final report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Griffith, J.W.; McCoy, R.M.
1986-11-01
An analysis of squirrel cage induction motor rotors was undertaken in response to an Industry Assessment Study finding 10% of motor failures to be rotor related. The analysis focuses on evaluating rotor design life. The evaluation combines state-of-the-art electromagnetic, thermal, and structural solution techniques into an integrated analysis and presents a simple summary. Finite element techniques are central tools in the analysis. The analysis is applied to a specific forced draft fan drive design. Fans as a category of application have a higher failure rate than other categories of power station auxiliary motor applications. Forced-draft fan drives are one ofmore » the major fan drives which accelerate a relatively high value of rotor load inertia. Various starting and operating conditions are studied for this forced-draft fan drive motor including a representative application duty cycle.« less
Angell, Linda S.
2014-01-01
A variety of methodologies for understanding the prevalence of distracted driving, its risk, and other aspects of driver secondary activity, have been used in the last 15 years. Although the current trend is toward naturalistic driving studies, each methodology contributes certain elements to a better understanding that could emerge from a convergence of these efforts. However, if differing methods are to contribute to a common and robust understanding of driver distraction, it is critical to understand the strengths and limitations of each method. This paper reviews several of the non-naturalistic methods. It suggests that “convergence science” – a more concerted and rigorous effort to bring different approaches together into an integrative whole – may offer benefits for identification and definition of issues and countermeasure development to improve driving safety. PMID:24776226
Inversion for the driving forces of plate tectonics
NASA Technical Reports Server (NTRS)
Richardson, R. M.
1983-01-01
Inverse modeling techniques have been applied to the problem of determining the roles of various forces that may drive and resist plate tectonic motions. Separate linear inverse problems have been solved to find the best fitting pole of rotation for finite element grid point velocities and to find the best combination of force models to fit the observed relative plate velocities for the earth's twelve major plates using the generalized inverse operator. Variance-covariance data on plate motion have also been included. Results emphasize the relative importance of ridge push forces in the driving mechanism. Convergent margin forces are smaller by at least a factor of two, and perhaps by as much as a factor of twenty. Slab pull, apparently, is poorly transmitted to the surface plate as a driving force. Drag forces at the base of the plate are smaller than ridge push forces, although the sign of the force remains in question.
Overview of automated enforcement in transportation
DOT National Transportation Integrated Search
1998-06-01
Automated enforcement is seen by some public agencies as a means to combat aggressive driving behaviors such as speeding or running red lights. Based upon a review of automated enforcement programs worldwide, several elements were found to be importa...
Copper-containing zeolite catalysts
Price, G.L.; Kanazirev, V.
1996-12-10
A catalyst useful in the conversion of nitrogen oxides or in the synthesis of nitriles or imines from amines, is formed by preparing an intimate mechanical mixture of a copper (II)-containing species, such as CuO or CuCl{sub 2}, or elemental copper, with a zeolite having a pore mouth comprising 10 oxygen atoms, such as ZSM-5, converting the elemental copper or copper (II) to copper (I), and driving the copper (I) into the zeolite.
Copper-containing zeolite catalysts
Price, Geoffrey L.; Kanazirev, Vladislav
1996-01-01
A catalyst useful in the conversion of nitrogen oxides or in the synthesis of nitriles or imines from amines, formed by preparing an intimate mechanical mixture of a copper (II)-containing species, such as CuO or CuCl.sub.2, or elemental copper, with a zeolite having a pore mouth comprising 10 oxygen atoms, such as ZSM-5, converting the elemental copper or copper (II) to copper (I), and driving the copper (I) into the zeolite.
NASA Technical Reports Server (NTRS)
Larson, V. R.; Gunn, S. V.; Lee, J. C.
1975-01-01
The paper describes a helium heater to be used to conduct non-nuclear demonstration tests of the complete power conversion loop for a direct-cycle gas-cooled nuclear reactor power plant. Requirements for the heater include: heating the helium to a 1500 F temperature, operating at a 1000 psia helium pressure, providing a thermal response capability and helium volume similar to that of the nuclear reactor, and a total heater system helium pressure drop of not more than 15 psi. The unique compact heater system design proposed consists of 18 heater modules; air preheaters, compressors, and compressor drive systems; an integral control system; piping; and auxiliary equipment. The heater modules incorporate the dual-concentric-tube 'Variflux' heat exchanger design which provides a controlled heat flux along the entire length of the tube element. The heater design as proposed will meet all system requirements. The heater uses pressurized combustion (50 psia) to provide intensive heat transfer, and to minimize furnace volume and heat storage mass.
NASA Astrophysics Data System (ADS)
Park, Sangki; Woo, Seungchul; Kim, Minho; Lee, Kihyung
2017-04-01
The design and evaluation of engine cooling and lubrication systems is generally based on real vehicle tests. Our goal here was to establish an engine heat balance model based on mathematical and interpretive analysis of each element of a passenger diesel engine cooling system using a 1-D numerical model. The purpose of this model is to determine ways of optimizing the cooling and lubrication components of an engine and then to apply these methods to actual cooling and lubrication systems of engines that will be developed in the future. Our model was operated under the New European Driving Cycle (NEDC) mode conditions, which represent the fuel economy evaluation mode in Europe. The flow rate of the cooling system was controlled using a control valve. Our results showed that the fuel efficiency was improved by as much as 1.23 %, cooling loss by 1.35 %, and friction loss by 2.21 % throughout NEDC modes by modification of control conditions.