Optimization of the Efficiency of a Neutron Detector to Measure (α, n) Reaction Cross-Section

NASA Astrophysics Data System (ADS)

Perello, Jesus; Montes, Fernando; Ahn, Tony; Meisel, Zach; Joint InstituteNuclear Astrophysics Team

2015-04-01

Nucleosynthesis, the origin of elements, is one of the greatest mysteries in physics. A recent particular nucleosynthesis process of interest is the charge-particle process (cpp). In the cpp, elements form by nuclear fusion reactions during supernovae. This process of nuclear fusion, (α,n), will be studied by colliding beam elements produced and accelerated at the National Superconducting Cyclotron Laboratory (NSCL) to a helium-filled cell target. The elements will fuse with α (helium nuclei) and emit neutrons during the reaction. The neutrons will be detected for a count of fused-elements, thus providing us the probability of such reactions. The neutrons will be detected using the Neutron Emission Ratio Observer (NERO). Currently, NERO's efficiency varies for neutrons at the expected energy range (0-12 MeV). To study (α,n), NERO's efficiency must be near-constant at these energies. Monte-Carlo N-Particle Transport Code (MCNP6), a software package that simulates nuclear processes, was used to optimize NERO configuration for the experiment. MCNP6 was used to simulate neutron interaction with different NERO configurations at the expected neutron energies. By adding additional 3He detectors and polyethylene, a near-constant efficiency at these energies was obtained in the simulations. With the new NERO configuration, study of the (α,n) reactions can begin, which may explain how elements are formed in the cpp. SROP MSU, NSF, JINA, McNair Society.

40 CFR 761.30 - Authorizations.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Current-limiting fuses or other equivalent technology must be used to detect sustained high current faults... fuses or other equivalent technology to avoid PCB Transformer ruptures from sustained high current... protection, such as current-limiting fuses or other equivalent technology, to detect sustained high current...

Observation of changes in the metallurgical characteristics of Ni-Cr alloys using Nd:YAG laser welding

PubMed Central

Choi, SM

2014-01-01

This study aimed to determine the effect of hardness change according to penetration depth in the laser fusing zone and observed the correlation of the microstructure as an Nd:YAG laser was irradiated to Ni-Cr alloy for dental use by setting the spot diameter size to various conditions. In all groups, the hardness depth profiles in the laser fusing zone and heat-affected zone (HAZ) had larger values than those of the base metal. In addition, the hardness values in places beyond the fusing zone and the HAZ were measured as being quantitatively lower. The observation result of the diffusion of the constituent elements and microstructure using field emission scanning electron microscopy, energy-dispersive spectroscopy, and electron probe microanalyzer showed that the fusing zone revealed a much finer dendritic form than the base metal due to the self-quenching effect after welding, while no change in constituent elements was found although some evaporation of the main elements was observed. In addition, Mo- and Si-combined intermetallic compounds were formed on the interdendritic area. Through this study, the laser fusing zone had better hardenability due to the intermetallic compound and grain refinement effect. PMID:25342985

Halting the fuse discharge propagation using optical fiber microwires.

PubMed

Rocha, A M; Fernandes, G; Domingues, F; Niehus, M; Pinto, A N; Facão, M; André, P S

2012-09-10

We report and analyze the halting of the fuse effect propagation in optical fiber microwires. The increase of the mode field diameter in the tapered region decreases the optical intensity resulting in the extinction of the fuse effect. This fiber element presents a low insertion loss and can be introduced in the optical network in order to protect the active equipment from the damage caused by the fuse effect.

Internal fuse modules for solid tantalum capacitors

NASA Technical Reports Server (NTRS)

Dematos, H. V.

1981-01-01

Miniature fuse modules were designed for and incorporated into two styles of solid tantalum capacitors. One is an epoxy molded, radial leaded, high frequency decoupling capacitor; the other is an hermetically sealed device with axial lead wires. The fusible element for both devices consists of a fine bimetallic wire which reacts exothermically upon reaching a critical temperature and then disintegrates. The desirability of having fused devices is discussed and design constraints, in particular those which minimize inductance and series resistance while optimizing fuse actuation characteristics, are reviewed. Factors affecting the amount of energy required to actuate the fuse and reliability of acuation are identified.

Launch of NASA's FUSE satellite from CCAS.

NASA Technical Reports Server (NTRS)

1999-01-01

The Boeing Delta II rocket carrying NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite clears the tower after liftoff at 11:44 a.m. EDT from Launch Pad 17A, Cape Canaveral Air Station. FUSE was developed to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum.

Launch of NASA's FUSE satellite from CCAS.

NASA Technical Reports Server (NTRS)

1999-01-01

NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite sits on Launch Pad 17A, Cape Canaveral Air Station, aboard the Boeing Delta II rocket waiting for launch. Liftoff is scheduled for 11:39 a.m. EDT. FUSE was developed to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum.

Workers at CCAS attach solar panel to FUSE satellite.

NASA Technical Reports Server (NTRS)

1999-01-01

At Hangar AE, Cape Canaveral Air Station (CCAS), workers move a solar panel toward NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite before attaching it. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is targeted for launch June 23 from Launch Pad 17A, CCAS, aboard a Boeing Delta II rocket.

Workers at CCAS attach solar panel to FUSE satellite.

NASA Technical Reports Server (NTRS)

1999-01-01

At Hangar AE, Cape Canaveral Air Station (CCAS), workers check the installation of a solar panel on NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is targeted for launch June 23 from Launch Pad 17A, CCAS, aboard a Boeing Delta II rocket.

Workers at CCAS attach solar panel to FUSE satellite.

NASA Technical Reports Server (NTRS)

1999-01-01

At Hangar AE, Cape Canaveral Air Station (CCAS), workers attach a solar panel to NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is targeted for launch June 23 from Launch Pad 17A, CCAS, aboard a Boeing Delta II rocket.

The canister around the FUSE satellite is removed on the pad at CCAS.

NASA Technical Reports Server (NTRS)

1999-01-01

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), workers begin to remove the canister around the top of the NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study hydrogen and deuterium to unlock the secrets of how the primordial chemical elements of which all stars, planets and life evolved, were created and distributed since the birth of the universe. FUSE is scheduled to be launched from CCAS June 23 aboard a Boeing Delta II rocket.

The canister around the FUSE satellite is removed on the pad at CCAS.

NASA Technical Reports Server (NTRS)

1999-01-01

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), workers oversee the removal of the canister from the top of NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study hydrogen and deuterium to unlock the secrets of how the primordial chemical elements of which all stars, planets and life evolved, were created and distributed since the birth of the universe. FUSE is scheduled to be launched from CCAS June 23 aboard a Boeing Delta II rocket.

KSC-99pp0701

NASA Image and Video Library

1999-06-17

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), workers remove another section of the canister surrounding NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study hydrogen and deuterium to unlock the secrets of how the primordial chemical elements of which all stars, planets and life evolved, were created and distributed since the birth of the universe. FUSE is scheduled to be launched from CCAS June 23 aboard a Boeing Delta II rocket

High strength fused silica flexures manufactured by femtosecond laser

NASA Astrophysics Data System (ADS)

Bellouard, Yves; Said, Ali A.; Dugan, Mark; Bado, Philippe

2009-02-01

Flexures are mechanical elements used in micro- and precision-engineering to precisely guide the motion of micro-parts. They consist of slender bodies that deform elastically upon the application of a force. Although counter-intuitive at first, fused silica is an attractive material for flexure. Pending that the machining process does not introduce surface flaws that would lead to catastrophic failure, the material has a theoretically high ultimate tensile strength of several GPa. We report on high-aspect ratio fused silica flexures manufactured by femtosecond laser combined with chemical etching. Notch-hinges with thickness as small as twenty microns and aspect ratios comparable to aspect ratios obtained by Deep- Reactive-Ion-Etching (DRIE) were fabricated and tested under different loading conditions. Multiple fracture tests were performed for various loading conditions and the cracks morphologies were analyzed using Scanning Electron Microscopy. The manufactured elements show outstanding mechanical properties with flexural strengths largely exceeding those obtained with other technologies and materials. Fused silica flexures offer a mean to combine integrated optics with micro-mechanics in a single monolithic substrate. Waveguides and mechanical elements can be combined in a monolithic devices opening new opportunities for integrated opto-mechatronics devices.

Development of Fuses for Protection of Geiger-Mode Avalanche Photodiode Arrays

NASA Astrophysics Data System (ADS)

Grzesik, Michael; Bailey, Robert; Mahan, Joe; Ampe, Jim

2015-11-01

Current-limiting fuses composed of Ti/Al/Ni were developed for use in Geiger-mode avalanche photodiode arrays for each individual pixel in the array. The fuses were designed to burn out at ˜4.5 × 10-3 A and maintain post-burnout leakage currents less than 10-7 A at 70 V sustained for several minutes. Experimental fuse data are presented and successful incorporation of the fuses into a 256 × 64 pixel InP-based Geiger-mode avalanche photodiode array is reported.

Workers at CCAS attach solar panel to FUSE satellite.

NASA Technical Reports Server (NTRS)

1999-01-01

At Hangar AE, Cape Canaveral Air Station (CCAS), workers get ready to move a solar panel to be attached to NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite in the background. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is targeted for launch June 23 from Launch Pad 17A, CCAS, aboard a Boeing Delta II rocket.

Boeing Delta II rocket for FUSE launch arrives at CCAS

NASA Technical Reports Server (NTRS)

1999-01-01

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), the first stage of a Boeing Delta II rocket is moved into the tower. The rocket is targeted to launch NASA's Far Ultraviolet Spectroscopic Explorer (FUSE), developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md. FUSE will investigate the origin and evolution of the lightest elements in the universe, hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is scheduled to be launched June 23 at CCAS.

The FUSE satellite is encased in a canister before being moved to the Launch Pad.

NASA Technical Reports Server (NTRS)

1999-01-01

NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite is fitted with another row of canister segments before being moved to Launch Pad 17A, CCAS. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is scheduled to be launched June 23 aboard a Boeing Delta II rocket.

Boeing Delta II rocket for FUSE launch arrives at CCAS

NASA Technical Reports Server (NTRS)

1999-01-01

After its arrival at Launch Pad 17A, Cape Canaveral Air Station (CCAS), the first stage of a Boeing Delta II rocket is raised to a vertical position. The rocket is targeted to launch NASA's Far Ultraviolet Spectroscopic Explorer (FUSE), developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md. FUSE will investigate the origin and evolution of the lightest elements in the universe, hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is scheduled to be launched June 23 at CCAS.

Boeing Delta II rocket for FUSE launch arrives at CCAS

NASA Technical Reports Server (NTRS)

1999-01-01

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), the first stage of a Boeing Delta II rocket is raised for its journey up the launch tower. The rocket is targeted to launch NASA's Far Ultraviolet Spectroscopic Explorer (FUSE), developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md. FUSE will investigate the origin and evolution of the lightest elements in the universe, hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is scheduled to be launched June 23 at CCAS.

Boeing Delta II rocket for FUSE launch arrives at CCAS

NASA Technical Reports Server (NTRS)

1999-01-01

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), the first stage of a Boeing Delta II rocket is ready to be lifted into the tower. The rocket is targeted to launch NASA's Far Ultraviolet Spectroscopic Explorer (FUSE), developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md. FUSE will investigate the origin and evolution of the lightest elements in the universe,hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is scheduled to be launched June 23 at CCAS.

1 mil gold bond wire study.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huff, Johnathon; McLean, Michael B.; Jenkins, Mark W.

2013-05-01

In microcircuit fabrication, the diameter and length of a bond wire have been shown to both affect the current versus fusing time ratio of a bond wire as well as the gap length of the fused wire. This study investigated the impact of current level on the time-to-open and gap length of 1 mil by 60 mil gold bond wires. During the experiments, constant current was provided for a control set of bond wires for 250ms, 410ms and until the wire fused; non-destructively pull-tested wires for 250ms; and notched wires. The key findings were that as the current increases, themore » gap length increases and 73% of the bond wires will fuse at 1.8A, and 100% of the wires fuse at 1.9A within 60ms. Due to the limited scope of experiments and limited data analyzed, further investigation is encouraged to confirm these observations.« less

KSC-99pp0700

NASA Image and Video Library

1999-06-17

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), workers begin removing the lower sections of the canister surrounding NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study hydrogen and deuterium to unlock the secrets of how the primordial chemical elements of which all stars, planets and life evolved, were created and distributed since the birth of the universe. FUSE is scheduled to be launched from CCAS June 23 aboard a Boeing Delta II rocket

KSC-99pp0699

NASA Image and Video Library

1999-06-17

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), workers oversee the removal of the canister from the top of NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study hydrogen and deuterium to unlock the secrets of how the primordial chemical elements of which all stars, planets and life evolved, were created and distributed since the birth of the universe. FUSE is scheduled to be launched from CCAS June 23 aboard a Boeing Delta II rocket

KSC-99pp0698

NASA Image and Video Library

1999-06-17

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), workers begin to remove the canister around the top of the NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study hydrogen and deuterium to unlock the secrets of how the primordial chemical elements of which all stars, planets and life evolved, were created and distributed since the birth of the universe. FUSE is scheduled to be launched from CCAS June 23 aboard a Boeing Delta II rocket

KSC-99pp0703

NASA Image and Video Library

1999-06-17

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), workers look over NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite after sections of the canister have been removed. FUSE is scheduled to be launched from CCAS June 23 aboard a Boeing Delta II rocket. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study hydrogen and deuterium to unlock the secrets of how the primordial chemical elements of which all stars, planets and life evolved, were created and distributed since the birth of the universe

KSC-99pp0690

NASA Image and Video Library

1999-06-14

NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite is fitted with another row of canister segments before being moved to Launch Pad 17A, CCAS. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is scheduled to be launched June 23 aboard a Boeing Delta II rocket

KSC-99pp0663

NASA Image and Video Library

1999-06-12

At Hangar AE, Cape Canaveral Air Station (CCAS), workers attach a solar panel to NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is targeted for launch June 23 from Launch Pad 17A, CCAS, aboard a Boeing Delta II rocket

Launch of NASA's FUSE satellite from CCAS.

NASA Technical Reports Server (NTRS)

1999-01-01

As light peers over the horizon at the crack of dawn, NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite waits for launch on Launch Pad 17A, Cape Canaveral Air Station, aboard the Boeing Delta II rocket. Liftoff is scheduled for 11:39 a.m. EDT. FUSE was developed to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum.

Launch of NASA's FUSE satellite from CCAS.

NASA Technical Reports Server (NTRS)

1999-01-01

Clouds of smoke and steam billow around the Boeing Delta II rocket as it roars into the sky after liftoff at 11:44 a.m. EDT from Launch Pad 17A, Cape Canaveral Air Station. The rocket is carrying NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE was developed to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum.

15. VIEW OF DUMMY FUEL ELEMENT ON FUEL ELEMENT HOLDER. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. VIEW OF DUMMY FUEL ELEMENT ON FUEL ELEMENT HOLDER. SHOWS AIR FORCE MAN AT EDGE OF TANK. INEL PHOTO NUMBER 65-6176, TAKEN NOVEMBER 10, 1965. - Idaho National Engineering Laboratory, Advanced Reentry Vehicle Fusing System, Scoville, Butte County, ID

FUSE Observations of Heavy Elements in the Photospheres of Cool DB White Dwarfs

NASA Astrophysics Data System (ADS)

Desharnais, S.; Wesemael, F.; Chayer, P.; Kruk, J. W.; Saffer, R. A.

2008-01-01

We present a comprehensive analysis of the far-ultraviolet spectra of five DB white dwarfs spanning the effective temperature range between 14,700 and 20,800 K. The FUSE line analysis shows that carbon features, previously observed in several hot DB stars at or above 22,000 K, are present in the two coolest (GD 408 and GD 378) and in the hottest (G270-124) target. The observed carbon abundances range from log N(C)/N(He) ~ - 6.9 to ~ - 8.8. In addition, four of the five objects display photospheric lines of silicon. Other elements such as oxygen, iron, and sulfur are also observed in some objects. The variations of the abundances of heavy elements as a function of effective temperature in DB stars are discussed in terms of a competition between a stellar wind, gravitational settling, accretion from interstellar (and circumstellar) matter, and convective dredge-up. FUSE is operated by the Johns Hopkins University under NASA contract NAS5-32985.

KSC-99pp0494

NASA Image and Video Library

1999-05-03

Workers at Hangar AE, Cape Canaveral Air Station, maneuver an overhead crane toward NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite standing between vertical workstands. The crane will lift FUSE to move it onto the Payload Attach Fitting (PAF) in front of it. FUSE is undergoing a functional test of its systems, plus installation of flight batteries and solar arrays. Developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., FUSE will investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is scheduled to be launched May 27 aboard a Boeing Delta II rocket at Launch Complex 17

KSC-99pp0496

NASA Image and Video Library

1999-05-04

Suspended by a crane in Hangar AE, Cape Canaveral Air Station, NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite is lowered onto a circular Payload Attach Fitting (PAF). FUSE is undergoing a functional test of its systems, plus installation of flight batteries and solar arrays. Developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., FUSE will investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is scheduled to be launched May 27 aboard a Boeing Delta II rocket at Launch Complex 17

Self-healing fuse development.

NASA Technical Reports Server (NTRS)

Jones, N. D.

1972-01-01

The self-healing fuse is a very fast acting current overload protective device which opens and recloses in a few milliseconds. The fuse confines a mercury column in an insulated channel and returns the mercury to the channel after firing. Ratings 5 to 50 A at 600 peak volts are possible with a life of hundreds of cycles. Compared to conventional fuses, much less fault current energy fires the fuse by heating the mercury to boiling temperature. Next an arc discharge develops while explosive forces expel the liquid mercury from the channel. Then the high impedance arc either extinguishes immediately, or operates for a few milliseconds, until a switch opens the circuit.

Divergent Binding and Transactivation by Two Related Steroid Receptors at the Same Response Element*

PubMed Central

Tesikova, Martina; Dezitter, Xavier; Nenseth, Hatice Z.; Klokk, Tove I.; Mueller, Florian; Hager, Gordon L.; Saatcioglu, Fahri

2016-01-01

Transcription factor (TF) recruitment to chromatin is central to activation of transcription. TF-chromatin interactions are highly dynamic, which are evaluated by recovery half time (t1/2) in seconds, determined by fluorescence recovery experiments in living cells, and chromatin immunoprecipitation (ChIP) analysis, measured in minutes. These two states are related: the larger the t1/2, the longer the ChIP occupancy resulting in increased transcription. Here we present data showing that this relationship does not always hold. We found that histone deacetylase inhibitors (HDACis) significantly increased t1/2 of green fluorescent protein (GFP) fused androgen receptor (AR) on a tandem array of positive hormone response elements (HREs) in chromatin. This resulted in increased ChIP signal of GFP-AR. Unexpectedly, however, transcription was inhibited. In contrast, the GFP-fused glucocorticoid receptor (GR), acting through the same HREs, displayed a profile consistent with current models. We provide evidence that these differences are mediated, at least in part, by HDACs. Our results provide insight into TF action in living cells and show that very closely related TFs may trigger significantly divergent outcomes at the same REs. PMID:27056330

29 CFR 1926.449 - Definitions applicable to this subpart.

Code of Federal Regulations, 2010 CFR

2010-07-01

... disconnecting blade. The fuseholder or fuse carrier may include a conducting element (fuse link), or may act as the disconnecting blade by the inclusion of a nonfusible member. Cutout box. An enclosure designed for... manner; (b) Inspecting the run of such items of equipment and materials at factories for product...

29 CFR 1926.449 - Definitions applicable to this subpart.

Code of Federal Regulations, 2012 CFR

2012-07-01

... disconnecting blade. The fuseholder or fuse carrier may include a conducting element (fuse link), or may act as the disconnecting blade by the inclusion of a nonfusible member. Cutout box. An enclosure designed for... manner; (b) Inspecting the run of such items of equipment and materials at factories for product...

29 CFR 1926.449 - Definitions applicable to this subpart.

Code of Federal Regulations, 2011 CFR

2011-07-01

... disconnecting blade. The fuseholder or fuse carrier may include a conducting element (fuse link), or may act as the disconnecting blade by the inclusion of a nonfusible member. Cutout box. An enclosure designed for... manner; (b) Inspecting the run of such items of equipment and materials at factories for product...

29 CFR 1926.449 - Definitions applicable to this subpart.

Code of Federal Regulations, 2013 CFR

2013-07-01

... disconnecting blade. The fuseholder or fuse carrier may include a conducting element (fuse link), or may act as the disconnecting blade by the inclusion of a nonfusible member. Cutout box. An enclosure designed for... manner; (b) Inspecting the run of such items of equipment and materials at factories for product...

29 CFR 1926.449 - Definitions applicable to this subpart.

Code of Federal Regulations, 2014 CFR

2014-07-01

... disconnecting blade. The fuseholder or fuse carrier may include a conducting element (fuse link), or may act as the disconnecting blade by the inclusion of a nonfusible member. Cutout box. An enclosure designed for... manner; (b) Inspecting the run of such items of equipment and materials at factories for product...

KSC-99pp0665

NASA Image and Video Library

1999-06-12

At Hangar AE, Cape Canaveral Air Station (CCAS), workers check the installation of a solar panel on NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is targeted for launch June 23 from Launch Pad 17A, CCAS, aboard a Boeing Delta II rocket

KSC-99pp0666

NASA Image and Video Library

1999-06-12

Workers at Hangar AE, Cape Canaveral Air Station (CCAS), get ready to move the scaffolding from around NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE is targeted for launch June 23 from Launch Pad 17A, CCAS, aboard a Boeing Delta II rocket. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99pp0647

NASA Image and Video Library

1999-06-03

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), the first stage of a Boeing Delta II rocket is moved into the tower. The rocket is targeted to launch NASA's Far Ultraviolet Spectroscopic Explorer (FUSE), developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md. FUSE will investigate the origin and evolution of the lightest elements in the universe ¾ hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is scheduled to be launched June 23 at CCAS

KSC-99pp0664

NASA Image and Video Library

1999-06-12

At Hangar AE, Cape Canaveral Air Station (CCAS), workers move a solar panel toward NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite before attaching it. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is targeted for launch June 23 from Launch Pad 17A, CCAS, aboard a Boeing Delta II rocket

The canister around the FUSE satellite is removed on the pad at CCAS.

NASA Technical Reports Server (NTRS)

1999-01-01

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), workers check out the protective cover placed over the top of NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. The satellite is scheduled to be launched from CCAS June 23 aboard a Boeing Delta II rocket. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study hydrogen and deuterium to unlock the secrets of how the primordial chemical elements of which all stars, planets and life evolved, were created and distributed since the birth of the universe.

KSC-99pp0743

NASA Image and Video Library

1999-06-24

The Boeing Delta II rocket carrying NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite clears the tower after liftoff at 11:44 a.m. EDT from Launch Pad 17A, Cape Canaveral Air Station. FUSE was developed to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99pp0740

NASA Image and Video Library

1999-06-24

NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite sits on Launch Pad 17A, Cape Canaveral Air Station, aboard the Boeing Delta II rocket waiting for launch. Liftoff is scheduled for 11:39 a.m. EDT. FUSE was developed to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99pp0380

NASA Image and Video Library

1999-04-05

Workers in Hangar AE, Cape Canaveral Air Station, begin removing the plastic covering from NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite before prelaunch processing. FUSE will undergo a functional test of its systems, followed by installation of the flight batteries and solar arrays. Tests are also scheduled for the communications and data systems linking FUSE with the spacecraft control center at The Johns Hopkins University, Baltimore, Md. FUSE was developed and will be operated by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md. FUSE will investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. The launch aboard a Boeing Delta II rocket is targeted for May 20 at Launch Complex 17

KSC-99pp0382

NASA Image and Video Library

1999-04-05

At Hangar AE, Cape Canaveral Air Station, NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite stands alone after workstands have been removed. As part of prelaunch processing, FUSE will undergo a functional test of its systems, followed by installation of the flight batteries and solar arrays. Tests are also scheduled for the communications and data systems linking FUSE with the spacecraft control center at The Johns Hopkins University, Baltimore, Md. FUSE was developed and will be operated by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md. FUSE will investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. The launch aboard a Boeing Delta II rocket is targeted for May 20 at Launch Complex 17

KSC-99pp0381

NASA Image and Video Library

1999-04-05

At Hangar AE, Cape Canaveral Air Station, NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite is unveiled before prelaunch processing. FUSE will undergo a functional test of its systems, followed by installation of the flight batteries and solar arrays. Tests are also scheduled for the communications and data systems linking FUSE with the spacecraft control center at The Johns Hopkins University, Baltimore, Md. FUSE was developed and will be operated by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md. FUSE will investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. The launch aboard a Boeing Delta II rocket is targeted for May 20 at Launch Complex 17

KSC-99pp0379

NASA Image and Video Library

1999-04-05

Workers in Hangar AE, Cape Canaveral Air Station, get ready to remove the protective shipping cover from NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite for prelaunch processing. FUSE will undergo a functional test of its systems, followed by installation of the flight batteries and solar arrays. Tests are also scheduled for the communications and data systems linking FUSE with the spacecraft control center at The Johns Hopkins University, Baltimore, Md. FUSE was developed and will be operated by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md. FUSE will investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. The launch aboard a Boeing Delta II rocket is targeted for May 20 at Launch Complex 17

KSC-99pp0495

NASA Image and Video Library

1999-05-04

While a crane lifts NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite, workers at Hangar AE, Cape Canaveral Air Station, help guide it toward the circular Payload Attach Fitting (PAF) in front of it. FUSE is undergoing a functional test of its systems, plus installation of flight batteries and solar arrays. Developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., FUSE will investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is scheduled to be launched May 27 aboard a Boeing Delta II rocket at Launch Complex 17

30 CFR 28.2 - Approved fuses.

Code of Federal Regulations, 2010 CFR

2010-07-01

... MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR TRAILING...-circuit protection for trailing cables in coal mines only where such fuses are: (1) The same in all...

KSC-99pp0662

NASA Image and Video Library

1999-06-12

At Hangar AE, Cape Canaveral Air Station (CCAS), workers get ready to move a solar panel to be attached to NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite in the background. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is targeted for launch June 23 from Launch Pad 17A, CCAS, aboard a Boeing Delta II rocket

KSC-99pp0657

NASA Image and Video Library

1999-06-07

Workers oversee the mating of the second stage with the first stage of a Boeing Delta II rocket, which will launch the NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE is NASA's Far Ultraviolet Spectroscopic Explorer satellite developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is scheduled to launch June 23 at Launch Pad 17A, Cape Canaveral Air Station

KSC-99pp0646

NASA Image and Video Library

1999-06-03

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), the first stage of a Boeing Delta II rocket is raised for its journey up the launch tower. The rocket is targeted to launch NASA's Far Ultraviolet Spectroscopic Explorer (FUSE), developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md. FUSE will investigate the origin and evolution of the lightest elements in the universe ¾ hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is scheduled to be launched June 23 at CCAS

KSC-99pp0648

NASA Image and Video Library

1999-06-03

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), the first stage of a Boeing Delta II rocket is ready to be lifted into the tower. The rocket is targeted to launch NASA's Far Ultraviolet Spectroscopic Explorer (FUSE), developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md. FUSE will investigate the origin and evolution of the lightest elements in the universe ¾ hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is scheduled to be launched June 23 at CCAS

KSC-99pp0645

NASA Image and Video Library

1999-06-03

After its arrival at Launch Pad 17A, Cape Canaveral Air Station (CCAS), the first stage of a Boeing Delta II rocket is raised to a vertical position. The rocket is targeted to launch NASA's Far Ultraviolet Spectroscopic Explorer (FUSE), developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md. FUSE will investigate the origin and evolution of the lightest elements in the universe ¾ hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. FUSE is scheduled to be launched June 23 at CCAS

KSC-99pp0719

NASA Image and Video Library

1999-06-19

Workers in the launch tower at Launch Pad 17A, Cape Canaveral Air Station, help guide the first segment of the fairing around NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. The satellite is scheduled for launch June 24 aboard a Boeing Delta II rocket. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study those elements to unlock the secrets of how galaxies evolve and to discover what the Universe was like when it was only a few minutes old

KSC-99pp0722

NASA Image and Video Library

1999-06-19

At Launch Pad 17A, Cape Canaveral Air Station, NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite (foreground) is partially covered by half of the fairing (behind it) that will protect it during launch. The satellite is scheduled for launch June 24 aboard a Boeing Delta II rocket. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study those elements to unlock the secrets of how galaxies evolve and to discover what the Universe was like when it was only a few minutes old

KSC-99pp0717

NASA Image and Video Library

1999-06-19

NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite sits ready for the fairing installation at Launch Pad 17A, Cape Canaveral Air Station. The satellite is scheduled for launch June 24 aboard a Boeing Delta II rocket. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study hydrogen and deuterium to unlock the secrets of how the primordial chemical elements of which all stars, planets and life evolved, were created and distributed since the birth of the universe

KSC-99pp0742

NASA Image and Video Library

1999-06-24

Clouds of smoke and steam billow around the Boeing Delta II rocket as it roars into the sky after liftoff at 11:44 a.m. EDT from Launch Pad 17A, Cape Canaveral Air Station. The rocket is carrying NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE was developed to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99padig003

NASA Image and Video Library

1999-06-24

KENNEDY SPACE CENTER, FLA. -- Against a light summer sky, the Boeing Delta II rocket carrying NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite roars into the atmosphere after liftoff at 11:44 a.m. EDT from Launch Pad 17A, Cape Canaveral Air Station. FUSE was developed to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99pp0741

NASA Image and Video Library

1999-06-24

As light peers over the horizon at the crack of dawn, NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite waits for launch on Launch Pad 17A, Cape Canaveral Air Station, aboard the Boeing Delta II rocket. Liftoff is scheduled for 11:39 a.m. EDT. FUSE was developed to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

Modelling of Electrical Conductivity of a Silver Plasma at Low Temperature

NASA Astrophysics Data System (ADS)

Pascal, Andre; William, Bussiere; Alain, Coulbois; Jean-Louis, Gelet; David, Rochette

2016-08-01

During the working of electrical fuses, inside the fuse element the silver ribbon first begins to melt, to vaporize and then a fuse arc appears between the two separated parts of the element. Second, the electrodes are struck and the burn-back phenomenon takes place. Usually, the silver ribbon is enclosed inside a cavity filled with silica sand. During the vaporization of the fuse element, one can consider that the volume is fixed so that the pressure increase appears to reach pressures higher than atmospheric pressure. Thus, in this paper two pressures, 1 atm and 10 atm, are considered. The electrical field inside the plasma can reach high values since the distance between the cathode surface and the anode surface varies with time. That is to say from zero cm to one cm order. So we consider various electrical fields: 102 V/m, 103 V/m, 5×103 V/m, 104 V/m at atmospheric pressure and 105 V/m at a pressure of 10 atm. This study is made in heavy species temperature range from 2,400 K to 10,000 K. To study the plasma created inside the electric fuse, we first need to determine some characteristics in order to justify some hypotheses. That is to say: are the classical approximations of the thermal plasmas physics justified? In other words: plasma frequency, the ideality of the plasma, the Debye-Hückel approximation and the drift velocity versus thermal velocity. These characteristics and assumptions are discussed and commented on in this paper. Then, an evaluation of non-thermal equilibrium versus considered electrical fields is given. Finally, considering the high mobility of electrons, we evaluate the electrical conductivities.

The Abundances of the Iron Group Elements in Early B Stars in the Magellanic Clouds

NASA Astrophysics Data System (ADS)

Peters, C.

FUSE observations of four sharp-lined early B main-sequence band stars in the Magellanic Clouds will be carried through to determine the abundances of the heavy elements, especially those of the Fe group. The FUSE spectral region contains numerous Fe III lines, including the resonance multiplet (UV1) near 1130 A that is excellent for abundance determinations and two strong multiplets of V III, an ion that does not produce measurable lines longward of 1200 A in metal-deficient stars. In addition there are several measurable lines from Cr III and Mn III. Although abundances of the Fe-peak elements are of interest because they are important for assessing opacities for stellar evolution calculations and the validity of theoretical calculations of explosive nucleosynthesis, ground-based studies do not yield this information because measurable lines from these species, except for a few Fe III lines, are found only in the UV spectral region. The abundances of heavy elements provide information on the production of such elements in previous generations of stars. From FUSE data obtained in Cycle 3 we are determining the abundances of the Fe group elements in two sharp-lined early B stars in the SMC (AV 304, a field star, and NGC346-637, a star in a mini-starburst cluster). This project will allow one to compare the abundances in AV 304 and NGC346-637 with those in the LMC and other regions in the SMC and look for asymmetry in heavy element production in the Magellanic Clouds.

Characterization of copper and nichrome wires for safety fuse

NASA Astrophysics Data System (ADS)

Murdani, E.

2016-11-01

Fuse is an important component of an electrical circuit to limiting the current through the electrical circuit for electrical equipment safety. Safety fuses are made of a conductor such as copper and nichrome wires. The aim of this research was to determine the maximum current that can flow in the conductor wires (copper and nichrome). In the experiment used copper and nichrome wires by varying the length of wires (0.2 cm to 20 cm) and diameter of wires (0.1, 0.2, 0.3, 0.4 and 0.5) mm until maximum current reached that marked by melted or broken wire. From this experiment, it will be obtained the dependences data of maximum current to the length and diameter of wires. All data are plotted and it's known as a standard curve. The standard curve will provide an alternative choice of replacing fuse wire according to the maximum current requirement, including the wire type (copper and nichrome wires) and wire dimensions (length and diameter of wire).

The FUSE satellite is encased in a canister before being moved to the Launch Pad.

NASA Technical Reports Server (NTRS)

1999-01-01

Workers at Hangar AE, Cape Canaveral Air Station (CCAS), adjust the canister segments they are installing around NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. The satellite is being prepared for its transfer to Launch Pad 17A, CCAS, and its scheduled launch June 23 aboard a Boeing Delta II rocket. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum.

The FUSE satellite is encased in a canister before being moved to the Launch Pad.

NASA Technical Reports Server (NTRS)

1999-01-01

Workers at Hangar AE, Cape Canaveral Air Station (CCAS), fit the second row of canister segments around NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. The satellite is being prepared for its transfer to Launch Pad 17A, CCAS, and its scheduled launch June 23 aboard a Boeing Delta II rocket. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum.

The FUSE satellite is encased in a canister before being moved to the Launch Pad.

NASA Technical Reports Server (NTRS)

1999-01-01

At Hangar AE, Cape Canaveral Air Station (CCAS), workers on scaffolding pull down a weather-proofing cover over the canister surrounding NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. The satellite will next be moved to Launch Pad 17A, CCAS, for its scheduled launch June 23 aboard a Boeing Delta II rocket. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum.

FUSE Observations of Neutron-Capture Elements in Wolf-Rayet Planetary Nebulae

NASA Astrophysics Data System (ADS)

Dinerstein, H.

We propose to obtain FUSE observations of planetary nebula central stars of the WC Wolf-Rayet ([WC]) class, in order to search for the products of neutron-capture processes in these stars and provide constraints on their evolutionary status. Although the origin of the [WC]'s is controversial, their H-deficient, C-rich surface compositions indicate that they have experienced a high degree of mixing and/or mass loss. Thus one might expect the nebulae they produce to show enhanced concentrations of He-burning and other nuclear products, such as nuclei produced by slow neutron capture during the AGB phase. We have already detected an absorption line from one such element, Germanium (Sterling, Dinerstein, & Bowers 2002), while conducting a search for H2 absorption from nebular molecular material FUSE GI programs A085 and B069). Since the strongest Ge enhancements were found in PNe with [WC] central stars, we propose to enlarge the sample of such objects observed by FUSE. THIS TEMPORARY AND PARTIAL SCRIPT COVERS ONE TARGET, HE 2-99, AND REQUESTS AN EXPOSURE TIME OF 15 KSEC. PHASE 2 INFORMATION FOR THE REMAINDER OF THE PROGRAM'S TOTAL TIME ALLOCATION OF 60 KSEC WILL BE SUBMITTED AT A LATER TIME.

59. VIEW OF FUSES AND A CURRENT TRANSFORMER LOCATED IN ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

59. VIEW OF FUSES AND A CURRENT TRANSFORMER LOCATED IN THE SIGNAL POWER CONDITIONING ROOM. THE CURRENT TRANSFORMER (UPPER RIGHT) IS AN INDUCTION COUPLED SENSOR WHICH IS USED TO REDUCE HIGH CURRENT TO ANALOGOUS LOW VALUES SAFE TO USE IN CONTROL ROOM CIRCUITRY. - New York, New Haven & Hartford Railroad, Cos Cob Power Plant, Sound Shore Drive, Greenwich, Fairfield County, CT

Considerations on thermic and mechanic processes that appear when 3D printing using ABS fused deposition modelling technology

NASA Astrophysics Data System (ADS)

Amza, Catalin Gheorghe; Niţoi, Dan Florin

2018-02-01

3D printers are of recent history, but with an extremely rapid evolution both in technology and hardware involved. At present excellent performances are reached in applications such as 3D printing of various Acrylonitrile butadiene styrene (ABS) plastic parts for house building using Fused Deposition Modelling technology. Nevertheless, the thermic and mechanic processes that appear when manufacturing such plastic components are quite complex. This aspect is very important, especially when one wants to optimize the manufacturing of parts with certain geometrical complexity. The Finite Element Analysis/Modelling (FEA/FEM) is among the few methods that can study the thermic transfer processes and shape modifications that can appear due to non-seamar behavior that takes place when the ABS plastic material is cooling down. The current papers present such an analysis when simulating the deposition of several strings of materials. A thermic analysis is made followed by a study of deformations that appear when the structure cools down.

KSC-99pp0702

NASA Image and Video Library

1999-06-17

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), workers check out the protective cover placed over the top of NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. The satellite is scheduled to be launched from CCAS June 23 aboard a Boeing Delta II rocket. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study hydrogen and deuterium to unlock the secrets of how the primordial chemical elements of which all stars, planets and life evolved, were created and distributed since the birth of the universe

KSC-99pp0668

NASA Image and Video Library

1999-06-12

NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite stands in the Hangar A&E, Cape Canaveral Air Station (CCAS), ready for its launch, targeted for June 23 from Launch Pad 17A, CCAS aboard a Boeing Delta II rocket. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

35. DETAILS AND SECTIONS OF FUEL ELEMENT SUPPORT PLATFORM, FUEL ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

35. DETAILS AND SECTIONS OF FUEL ELEMENT SUPPORT PLATFORM, FUEL ELEMENT HOLDER, TRIP MECHANISM COVER, AND OTHER DETAILS. F.C. TORKELSON DRAWING NUMBER 842-ARVFS-701-S-3. INEL INDEX CODE NUMBER: 075 0701 60 851 151977. - Idaho National Engineering Laboratory, Advanced Reentry Vehicle Fusing System, Scoville, Butte County, ID

Monolithic fiber optic sensor assembly

DOEpatents

Sanders, Scott

2015-02-10

A remote sensor element for spectrographic measurements employs a monolithic assembly of one or two fiber optics to two optical elements separated by a supporting structure to allow the flow of gases or particulates therebetween. In a preferred embodiment, the sensor element components are fused ceramic to resist high temperatures and failure from large temperature changes.

Subsurface defects of fused silica optics and laser induced damage at 351 nm.

PubMed

Hongjie, Liu; Jin, Huang; Fengrui, Wang; Xinda, Zhou; Xin, Ye; Xiaoyan, Zhou; Laixi, Sun; Xiaodong, Jiang; Zhan, Sui; Wanguo, Zheng

2013-05-20

Many kinds of subsurface defects are always present together in the subsurface of fused silica optics. It is imperfect that only one kind of defects is isolated to investigate its impact on laser damage. Therefore it is necessary to investigate the impact of subsurface defects on laser induced damage of fused silica optics with a comprehensive vision. In this work, we choose the fused silica samples manufactured by different vendors to characterize subsurface defects and measure laser induced damage. Contamination defects, subsurface damage (SSD), optical-thermal absorption and hardness of fused silica surface are characterized with time-of-flight secondary ion mass spectrometry (TOF-SIMS), fluorescence microscopy, photo-thermal common-path interferometer and fully automatic micro-hardness tester respectively. Laser induced damage threshold and damage density are measured by 351 nm nanosecond pulse laser. The correlations existing between defects and laser induced damage are analyzed. The results show that Cerium element and SSD both have a good correlation with laser-induced damage thresholds and damage density. Research results evaluate process technology of fused silica optics in China at present. Furthermore, the results can provide technique support for improving laser induced damage performance of fused silica.

The FUSE satellite is encased in a canister before being moved to the Launch Pad.

NASA Technical Reports Server (NTRS)

1999-01-01

At Hangar AE, Cape Canaveral Air Station (CCAS), workers move segments of the canister that will be installed around NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite in the background. The satellite is being prepared for its transfer to Launch Pad 17A, CCAS, and its scheduled launch June 23 aboard a Boeing Delta II rocket. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum.

The FUSE satellite is encased in a canister before being moved to the Launch Pad.

NASA Technical Reports Server (NTRS)

1999-01-01

At Hangar AE, Cape Canaveral Air Station (CCAS), the last segment is lifted over the top of NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite already encased in a protective canister. The satellite will next be moved to Launch Pad 17A, CCAS, for its scheduled launch June 23 aboard a Boeing Delta II rocket. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum.

30 CFR 28.4 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., assembles, or fabricates, or controls the design, manufacture, assembly, or fabrication of a fuse, and who... means a device, no less effective than an automatic circuit breaker, for use with direct current which... MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR TRAILING...

30 CFR 28.4 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., assembles, or fabricates, or controls the design, manufacture, assembly, or fabrication of a fuse, and who... means a device, no less effective than an automatic circuit breaker, for use with direct current which... MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR TRAILING...

30 CFR 28.4 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., assembles, or fabricates, or controls the design, manufacture, assembly, or fabrication of a fuse, and who... means a device, no less effective than an automatic circuit breaker, for use with direct current which... MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR TRAILING...

Far Ultraviolet Astronomy

NASA Technical Reports Server (NTRS)

Sonneborn, George; Rabin, Douglas M. (Technical Monitor)

2002-01-01

The Far Ultraviolet Spectroscopic Explorer (FUSE) is studying a wide range of astronomical problems in the 905-1187 Angstrom wavelength region through the use of high resolution spectroscopy. The FUSE bandpass forms a nearly optimal complement to the spectral coverage provided by the Hubble Space Telescope (HST), which extends down to approximately 1170 Angstroms. The photoionization threshold of atomic hydrogen (911 Angstroms) sets a natural short-wavelength limit for the FUV. FUSE was launched in June 1999 from Cape Canaveral, Florida, on a Delta II rocket into a 768 km circular orbit. Scientific observations started later that year. This spectral region is extremely rich in spectral diagnostics of astrophysical gases over a wide range of temperatures (100 K to over 10 million K). Important strong spectral lines in this wavelength range include those of neutral hydrogen, deuterium, nitrogen, oxygen, and argon (H I, D I, N I, O I, and Ar I), molecular hydrogen (H2), five-times ionized oxygen (O VI), and several ionization states of sulfur (S III - S VI). These elements are essential for understanding the origin and evolution of the chemical elements, the formation of stars and our Solar System, and the structure of galaxies, including our Milky Way. FUSE is one of NASA's Explorer missions and a cooperative project of NASA and the space agencies of Canada and France. These missions are smaller, more scientifically focused missions than the larger observatories, like Hubble and Chandra. FUSE was designed, built and operated for NASA by the Department of Physics and Astronomy at Johns Hopkins University. Hundreds of astronomers world-wide are using FUSE for a wide range of scientific research. Some of the important scientific discoveries from the first two years of the mission are described.

200 kj copper foil fuses. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

McClenahan, C.R.; Goforth, J.H.; Degnan, J.H.

1980-04-01

A 200-kJ, 50-kV capacitor bank has been discharged into 1-mil-thick copper foils immersed in fine glass beads. These foils ranged in length from 27 to 71 cm and in width from 15 to 40 cm. Voltage spikes of over 250 kV were produced by the resulting fuse behavior of the foil. Moreover, the current turned off at a rate that was over 6 times the initial bank dI/dt. Full widths at half maxima for the voltage and dI/dt spikes were about 0.5 microsec, with some as short as 300 nanosec. Electrical breakdown was prevented in all but one size fuzemore » with maximum applied fields of 7 kV/cm. Fuses that were split into two parallel sections have been tested, and the effects relative to one-piece fuses are much larger than would be expected on the basis of inductance differences alone. A resistivity model for copper foil fuses, which differs from previous work in that it includes a current density dependence, has been devised. Fuse behavior is predicted with reasonable accuracy over a wide range of foil sizes by a quasi-two-dimensional fuse code that incorporates this resistivity model. A variation of Maisonnier's method for predicting optimum fuze size has been derived. This method is valid if the risetime of the bank exceeds 3 microsec, in which case it can be expected to be applicable over a wide range of peak current densities.« less

KSC-99pp0718

NASA Image and Video Library

1999-06-19

At Launch Pad 17A, Cape Canaveral Air Station, workers oversee the lifting of the fairing (right) into the tower. At left is NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite around which the fairing will be fitted. The satellite is scheduled for launch June 24 aboard a Boeing Delta II rocket. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study hydrogen and deuterium to unlock the secrets of how the primordial chemical elements of which all stars, planets and life evolved, were created and distributed since the birth of the universe

KSC-99pp0716

NASA Image and Video Library

1999-06-19

A camera is shown mounted on the second stage of the Boeing Delta II rocket scheduled to launch NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite June 24 from Launch Pad 17A, Cape Canaveral Air Station. The camera will record the separation of the fairing encircling the satellite, which should occur several minutes after launch. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study hydrogen and deuterium to unlock the secrets of how the primordial chemical elements of which all stars, planets and life evolved, were created and distributed since the birth of the universe

KSC-99pp0653

NASA Image and Video Library

1999-06-04

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), the launch tower again encircles the Boeing Delta II rocket after being mated with its solid rocket boosters. The rocket is targeted to launch NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) on June 23 at CCAS. Developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., FUSE will investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99pp0649

NASA Image and Video Library

1999-06-04

A solid rocket booster arrives at Launch Pad 17A, Cape Canaveral Air Station (CCAS), where it will be mated with the Boeing Delta II rocket in the background. The rocket is targeted to launch NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) on June 23 at CCAS. Developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., FUSE will investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99pp0651

NASA Image and Video Library

1999-06-04

Two solid rocket boosters are lifted up the tower on Launch Pad 17A, Cape Canaveral Air Station (CCAS), to be mated with a Boeing Delta II rocket. The rocket is targeted to launch NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) on June 23 at CCAS. Developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., FUSE will investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99pp0667

NASA Image and Video Library

1999-06-12

Workers at Hangar AE, Cape Canaveral Air Station (CCAS), check NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite after moving it from the scaffolding behind it. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. The satellite is targeted for launch June 23 from Launch Pad 17A, CCAS, aboard a Boeing Delta II rocket

KSC-99pp0652

NASA Image and Video Library

1999-06-04

At Launch Pad 17A, Cape Canaveral Air Station (CCAS), workers check the solid rocket boosters overhead being mated with the Boeing Delta II rocket already in place. The rocket is targeted to launch NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) on June 23 at CCAS. Developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., FUSE will investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99pp0650

NASA Image and Video Library

1999-06-04

A Boeing Delta II rocket sits on Launch Pad 17A, Cape Canaveral Air Station (CCAS), waiting to be mated with its solid rocket boosters. The rocket is targeted to launch NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) on June 23 at CCAS. Developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., FUSE will investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

Firefighters United for Safety, Ethics, and Ecology (FUSEE): Torchbearers for a new fire management paradigm

Treesearch

Timothy Ingalsbee; Joseph Fox; Patrick Withen

2007-01-01

Firefighters United for Safety, Ethics, and Ecology (FUSEE) is a nonprofit organization promoting safe, ethical, ecological wildland fire management. FUSEE believes firefighter and community safety are ultimately interdependent with ethical public service, wildlands protection, and ecological restoration of fire-adapted ecosystems. Our members include current, former,...

The FUSE satellite is ready to move to the launch pad.

NASA Technical Reports Server (NTRS)

1999-01-01

Standing in Hangar AE, Cape Canaveral Air Station (CCAS) is NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. The black rectangle on top is the optical port; at the lower right is the solar panel; behind (left) the lower edge of the panel are the radiators. The total length of the instrument is approximately four meters. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. Launch is targeted for June 23 from Launch Pad 17A, CCAS, aboard a Boeing Delta II rocket.

The FUSE satellite is ready to move to the launch pad.

NASA Technical Reports Server (NTRS)

1999-01-01

In Hangar AE, Cape Canaveral Air Station (CCAS), NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite stands ready to be moved to the launch pad. The black rectangle on top is the optical port; at the lower edge are the radiators. The total length of the instrument is approximately four meters. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. Launch is targeted for June 23 from Launch Pad 17A, CCAS, aboard a Boeing Delta II rocket.

The FUSE satellite is encased in a canister before being moved to the Launch Pad.

NASA Technical Reports Server (NTRS)

1999-01-01

At Hangar AE, Cape Canaveral Air Station (CCAS), workers get ready to finish erecting the canister around NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite at left. At right is the last segment which will be placed on the top. The satellite will next be moved to Launch Pad 17A, CCAS, for its scheduled launch June 23 aboard a Boeing Delta II rocket. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe - hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum.

34. DETAILS AND SECTIONS OF SHIELDING TANK FUEL ELEMENT SUPPORT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

34. DETAILS AND SECTIONS OF SHIELDING TANK FUEL ELEMENT SUPPORT FRAME. F.C. TORKELSON DRAWING NUMBER 842-ARVFS-701-S-4. INEL INDEX CODE NUMBER: 075 0701 60 851 151978. - Idaho National Engineering Laboratory, Advanced Reentry Vehicle Fusing System, Scoville, Butte County, ID

75 FR 5677 - Airworthiness Directives; The Boeing Company Model 767-200, -300, and -300F Series Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-04

... detailed and eddy current inspections to detect cracks and corrosion of certain midspar fuse pins, and... addition to longitudinal cracks. In addition, eddy current inspection of the midspar fuse pins in..., 311T3102-3, 311T3102-4, 311T2102-1 or 311T2102-2: Do a detailed inspection and an eddy current inspection...

Don't Blow a Fuse! Clever Exercise Tests Current-Measuring Skills

ERIC Educational Resources Information Center

Bentley, John

2005-01-01

The author has taught beginning, intermediate, and advanced electronics/electricity classes for more than 20 years. During that time--each and every semester--students struggle with measuring current in the laboratory. As all electronics/electricity instructors know, this results in blown fuses, burned parts, and just plain frustration on…

Redundancy Technology With A Focused Ion Beam

NASA Astrophysics Data System (ADS)

Komano, Haruki; Hashimoto, Kazuhiko; Takigawa, Tadahiro

1989-08-01

Fuse cutting with a focused ion beam to activate redundancy circuits is proposed. In order to verify its potential usefulness, experiments have been performed. Fuse-cutting time was evaluated using aluminum fuses with a thin passivation layer, which are difficult to cut by conventional laser-beam technology due to the material's high reflectivity. The fuse width and thickness were 2 and 0.8 μm, respectively. The fuse was cut in 5 seconds with a 30 keV focused ion beam of 0.3 A/cm2 current density. Since the fuses used in DRAMs will be smaller, their cutting time will become shorter by scanning an ion beam on narrower areas. Moreover, it can be shortened by increasing current density. Fuses for redundancy technology in 256 k CMOS SRAMs were cut with a focused ion beam. The operation of the memories was checked with a memory tester. It was confirmed that memories which had failure cells operated normally after focused-ion-beam fuse-cutting. Focused ion beam irradiation effects upon a device have been studied. When a 30 keV gallium focused ion beam was irradiated near the gate of MOSFETs, a threshold voltage shift was not observed at an ion dose of 0.3 C/cm2 which corresponded to the ion dose in cutting a fuse. However, when irradiated on the gate, a threshold voltage shift was observed at ion doses of more than 8 x 10-4 C/cm2. The voltage shift was caused by the charge of ions within the passivation layer. It is necessary at least not to irradiate a focused ion beam on a device in cutting fuses. It is concluded that the focused-ion-beam method will be advantageous for future redundancy technology application.

Imprinting high-gradient topographical structures onto optical surfaces using magnetorheological finishing: manufacturing corrective optical elements for high-power laser applications.

PubMed

Menapace, Joseph A; Ehrmann, Paul E; Bayramian, Andrew J; Bullington, Amber; Di Nicola, Jean-Michel G; Haefner, Constantin; Jarboe, Jeffrey; Marshall, Christopher; Schaffers, Kathleen I; Smith, Cal

2016-07-01

Corrective optical elements form an important part of high-precision optical systems. We have developed a method to manufacture high-gradient corrective optical elements for high-power laser systems using deterministic magnetorheological finishing (MRF) imprinting technology. Several process factors need to be considered for polishing ultraprecise topographical structures onto optical surfaces using MRF. They include proper selection of MRF removal function and wheel sizes, detailed MRF tool and interferometry alignment, and optimized MRF polishing schedules. Dependable interferometry also is a key factor in high-gradient component manufacture. A wavefront attenuating cell, which enables reliable measurement of gradients beyond what is attainable using conventional interferometry, is discussed. The results of MRF imprinting a 23 μm deep structure containing gradients over 1.6 μm / mm onto a fused-silica window are presented as an example of the technique's capabilities. This high-gradient element serves as a thermal correction plate in the high-repetition-rate advanced petawatt laser system currently being built at Lawrence Livermore National Laboratory.

Imprinting high-gradient topographical structures onto optical surfaces using magnetorheological finishing: Manufacturing corrective optical elements for high-power laser applications

DOE PAGES

Menapace, Joseph A.; Ehrmann, Paul E.; Bayramian, Andrew J.; ...

2016-03-15

Corrective optical elements form an important part of high-precision optical systems. We have developed a method to manufacture high-gradient corrective optical elements for high-power laser systems using deterministic magnetorheological finishing (MRF) imprinting technology. Several process factors need to be considered for polishing ultraprecise topographical structures onto optical surfaces using MRF. They include proper selection of MRF removal function and wheel sizes, detailed MRF tool and interferometry alignment, and optimized MRF polishing schedules. Dependable interferometry also is a key factor in high-gradient component manufacture. A wavefront attenuating cell, which enables reliable measurement of gradients beyond what is attainable using conventional interferometry,more » is discussed. The results of MRF imprinting a 23 μm deep structure containing gradients over 1.6 μm / mm onto a fused-silica window are presented as an example of the technique’s capabilities. As a result, this high-gradient element serves as a thermal correction plate in the high-repetition-rate advanced petawatt laser system currently being built at Lawrence Livermore National Laboratory.« less

KSC-99pp0688

NASA Image and Video Library

1999-06-14

Workers at Hangar AE, Cape Canaveral Air Station (CCAS), adjust the canister segments they are installing around NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. The satellite is being prepared for its transfer to Launch Pad 17A, CCAS, and its scheduled launch June 23 aboard a Boeing Delta II rocket. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99pp0689

NASA Image and Video Library

1999-06-14

Workers at Hangar AE, Cape Canaveral Air Station (CCAS), fit the second row of canister segments around NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. The satellite is being prepared for its transfer to Launch Pad 17A, CCAS, and its scheduled launch June 23 aboard a Boeing Delta II rocket. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99pp0687

NASA Image and Video Library

1999-06-14

At Hangar AE, Cape Canaveral Air Station (CCAS), workers move segments of the canister that will be installed around NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite in the background. The satellite is being prepared for its transfer to Launch Pad 17A, CCAS, and its scheduled launch June 23 aboard a Boeing Delta II rocket. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99pp0654

NASA Image and Video Library

1999-06-07

The second stage of a Boeing Delta II rocket is lifted up the launch tower at Launch Pad 17A, Cape Canaveral Air Station (CCAS). The first and second stages will be mated for the launch, targeted on June 23 at CCAS, of NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite,. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99pp0693

NASA Image and Video Library

1999-06-14

At Hangar AE, Cape Canaveral Air Station (CCAS), workers on scaffolding pull down a weather-proofing cover over the canister surrounding NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. The satellite will next be moved to Launch Pad 17A, CCAS, for its scheduled launch June 23 aboard a Boeing Delta II rocket. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99pp0655

NASA Image and Video Library

1999-06-07

The second stage of a Boeing Delta II rocket is moved inside the launch tower at Launch Pad 17A, Cape Canaveral Air Station (CCAS). The first and second stages will be mated for the launch, targeted on June 23 at CCAS, of NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99pp0692

NASA Image and Video Library

1999-06-14

At Hangar AE, Cape Canaveral Air Station (CCAS), the last segment is lifted over the top of NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite already encased in a protective canister. The satellite will next be moved to Launch Pad 17A, CCAS, for its scheduled launch June 23 aboard a Boeing Delta II rocket. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

Ionization of Local Interstellar Gas Based on STIS and FUSE spectra of Nearby Stars

NASA Astrophysics Data System (ADS)

Redfield, Seth; Linsky, J. L.

2009-01-01

The ultraviolet contains many resonance line transitions that are sensitive to a range of ionization stages of ions present in the local interstellar medium (LISM). We couple observations of high resolution ultraviolet spectrographs, STIS and GHRS on the Hubble Space Telescope (HST) and the Far-Ultraviolet Spectroscopic Explorer (FUSE) in order to make a comprehensive survey of the ionization structure of the local interstellar medium. In particular, we focus on the sight line toward G191-B2B, a nearby (69 pc) white dwarf. We present interstellar detections of highly ionized elements (e.g., SiIII, CIII, CIV, etc) and compare them directly to neutral or singly ionized LISM detections (e.g., SiII, CII, etc). The extensive observations of G191-B2B provides an opportunity for a broad study of ionization stages of several elements, while a survey of several sight lines provides a comprehensive look at the ionization structure of the LISM. We acknowledge support for this project through NASA FUSE Grant NNX06AD33G.

Femtosecond laser-induced structural difference in fused silica with a non-reciprocal writing process

NASA Astrophysics Data System (ADS)

Song, Hui; Dai, Ye; Song, Juan; Ma, Hongliang; Yan, Xiaona; Ma, Guohong

2017-04-01

In this paper, we report a non-reciprocal writing process for inducing asymmetric microstructure using a femtosecond laser with tilted pulse fronts in fused silica. The shape of the induced microstructure at the focus closely depends on the laser scan direction. An elongated end is observed as a kind of structural difference between the written lines with two reverse scans along + x and - x, which further leads to a birefringence intensity difference. We also find a bifurcation in the head region of the induced microstructure between the written lines along x and y. That process results from the focal intensity distortion caused by the pulse front tilt by comparing the simulated intensity distribution with the experimental results. The current results demonstrate that the pulse front tilt not only affects the free electron excitation at the focus but also further distorts the shape of the induced microstructure during a high-energy femtosecond laser irradiation. These results offer a route to fabricate optical elements by changing the spatiotemporal characteristics of ultrashort pulses.

Aviation Weather Information Requirements Study

NASA Technical Reports Server (NTRS)

Keel, Byron M.; Stancil, Charles E.; Eckert, Clifford A.; Brown, Susan M.; Gimmestad, Gary G.; Richards, Mark A.; Schaffner, Philip R. (Technical Monitor)

2000-01-01

The Aviation Safety Program (AvSP) has as its goal an improvement in aviation safety by a factor of 5 over the next 10 years and a factor of 10 over the next 20 years. Since weather has a big impact on aviation safety and is associated with 30% of all aviation accidents, Weather Accident Prevention (WxAP) is a major element under this program. The Aviation Weather Information (AWIN) Distribution and Presentation project is one of three projects under this element. This report contains the findings of a study conducted by the Georgia Tech Research Institute (GTRI) under the Enhanced Weather Products effort, which is a task under AWIN. The study examines current aviation weather products and there application. The study goes on to identify deficiencies in the current system and to define requirements for aviation weather products that would lead to an increase in safety. The study also provides an overview the current set of sensors applied to the collection of aviation weather information. New, modified, or fused sensor systems are identified which could be applied in improving the current set of weather products and in addressing the deficiencies defined in the report. In addition, the study addresses and recommends possible sensors for inclusion in an electronic pilot reporting (EPIREP) system.

36. DETAILS AND SECTIONS OF SHIELDING TANK, FUEL ELEMENT SUPPORT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

36. DETAILS AND SECTIONS OF SHIELDING TANK, FUEL ELEMENT SUPPORT FRAME AND SUPPORT PLATFORM, AND SAFETY MECHANISM ASSEMBLY (SPRING-LOADED HINGE). F.C. TORKELSON DRAWING NUMBER 842-ARVFS-701-S-1. INEL INDEX CODE NUMBER: 075 0701 60 851 151975. - Idaho National Engineering Laboratory, Advanced Reentry Vehicle Fusing System, Scoville, Butte County, ID

Fusing Social Media and Mobile Analytics for Urban Sense-Making

DTIC Science & Technology

2017-05-09

AFRL-AFOSR-JP-TR-2017-0037 Fusing Social Media and Mobile Analytics for Urban Sense-Making Archan Misra SINGAPORE MANAGEMENT UNIVERSITY Final Report...CONTRACT NUMBER 5b.  GRANT NUMBER FA2386-14-1-0002 5c.  PROGRAM ELEMENT NUMBER 61102F 6. AUTHOR(S) Archan Misra 5d.   PROJECT NUMBER 5e.  TASK...NUMBER 5f.  WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) SINGAPORE MANAGEMENT UNIVERSITY 81 VICTORIA STREET SINGAPORE, 188065 SG 8

KSC-99pp0720

NASA Image and Video Library

1999-06-19

A worker in the launch tower at Launch Pad 17A, Cape Canaveral Air Station, watches as the first segment of the fairing is maneuvered around NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. The satellite is scheduled for launch June 24 aboard a Boeing Delta II rocket. At the lower left in the photo can be seen a camera installed on the second stage of the rocket to record the separation of the fairing several minutes after launch. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study those elements to unlock the secrets of how galaxies evolve and to discover what the Universe was like when it was only a few minutes old

KSC-99pp0721

NASA Image and Video Library

1999-06-19

Workers in the launch tower at Launch Pad 17A, Cape Canaveral Air Station, help guide the first segment of the fairing around NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. The satellite is scheduled for launch June 24 aboard a Boeing Delta II rocket. At the lower left can be seen a camera installed on the second stage of the rocket to record the separation of the fairing several minutes after launch. FUSE is designed to scour the cosmos for the fossil record of the origins of the universe hydrogen and deuterium. Scientists will use FUSE to study those elements to unlock the secrets of how galaxies evolve and to discover what the Universe was like when it was only a few minutes old

KSC-99pp0691

NASA Image and Video Library

1999-06-14

At Hangar AE, Cape Canaveral Air Station (CCAS), workers get ready to finish erecting the canister around NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite at left. At right is the last segment which will be placed on the top. The satellite will next be moved to Launch Pad 17A, CCAS, for its scheduled launch June 23 aboard a Boeing Delta II rocket. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

KSC-99pp0656

NASA Image and Video Library

1999-06-07

Under the watchful eyes of workers at Launch Pad 17A, Cape Canaveral Air Station (CCAS), the second stage of a Boeing Delta II rocket is lowered toward the first stage below. The first and second stages will be mated for the launch, targeted on June 23 at CCAS, , of NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

Differentiation of cartilaginous anlagen in entire embryonic mouse limbs cultured in a rotating bioreactor

NASA Astrophysics Data System (ADS)

Montufar-Solis, D.; Oakley, C. R.; Jefferson, Y.; Duke, P. J.

2003-10-01

Mechanisms involved in development of the embryonic limb have remained the same throughout eons of genetic and environmental evolution under Earth gravity (lg). During the spaceflight era it has been of interest to explore the ancient theory that form of the skeleton develops in response to gravity, and that changes in gravitational forces can change the developmental pattern of the limb. This has been shown in vivo and in vitro, allowing the hypergravity of centrifugation and microgravity of space to be used as tools to increase our knowledge of limb development. In recapitulations of spaceflight experiments, premetatarsals were cultured in suspension in a bioreactor, and found to be shorter and less differentiated than those cultured in standard culture dishes. This study only measured length of the metatarsals, and did not account for possible changes due to the skeletal elements having a more in vivo 3D shape while in suspension vs. flattened tissues compressed by their own weight. A culture system with an outcome closer to in vivo and that supports growth of younger limb buds than traditional systems will allow studies of early Hox gene expression, and contribute to the understanding of very early stages of development. The purpose of the current experiment was to determine if entire limb buds could be cultured in the bioreactor, and to compare the growth and differentiation with that of culturing in a culture dish system. Fore and hind limbs from E11-E13 ICR mouse embryos were cultured for six days, either in the bioreactor or in center-well organ culture dishes, fixed, and embedded for histology. E13 specimens grown in culture dishes were flat, while bioreactor culture specimens had a more in vivo-like 3D limb shape. Sections showed excellent cartilage differentiation in both culture systems, with more cell maturation, and hypertrophy in the specimens cultured in the bioreactor. Younger limb buds fused together during culture, so an additional set of El 1.5 limb buds was cultured with and without encapsulation in alginate prior to culturing in the bioreactor. Encapsulated limbs grown in the bioreactor did not fuse together, but developed only the more proximal elements while limbs grown in culture dishes formed proximal and distal elements. Alginate encapsulation may have reduced oxygenation to the progress zone of the developing limb bud resulting in lack of development of the more distal elements. These results show that the bioreactor supports growth and differentiation of skeletal elements in entire E13 limb buds, and that a method to culture younger limb buds without fusing together needs to be developed if any morphometric analysis is to be performed.

Quartz/fused silica chip carriers

NASA Technical Reports Server (NTRS)

1992-01-01

The primary objective of this research and development effort was to develop monolithic microwave integrated circuit (MMIC) packaging which will operate efficiently at millimeter-wave frequencies. The packages incorporated fused silica as the substrate material which was selected due to its favorable electrical properties and potential performance improvement over more conventional materials for Ka-band operation. The first step towards meeting this objective is to develop a package that meets standard mechanical and thermal requirements using fused silica and to be compatible with semiconductor devices operating up to at least 44 GHz. The second step is to modify the package design and add multilayer and multicavity capacity to allow for application specific integrated circuits (ASIC's) to control multiple phase shifters. The final step is to adapt the package design to a phased array module with integral radiating elements. The first task was a continuation of the SBIR Phase 1 work. Phase 1 identified fused silica as a viable substrate material by demonstrating various plating, machining, and adhesion properties. In Phase 2 Task 1, a package was designed and fabricated to validate these findings. Task 2 was to take the next step in packaging and fabricate a multilayer, multichip module (MCM). This package is the predecessor to the phased array module and demonstrates the ability to via fill, circuit print, laminate, and to form vertical interconnects. The final task was to build a phased array module. The radiating elements were to be incorporated into the package instead of connecting to it with wire or ribbon bonds.

HRATIS first year evaluation report

DOT National Transportation Integrated Search

2001-09-01

The ITS integration project, the Hampton Roads Advanced Traveler Information System (HRATIS), is a public-private partnership. The service collects information from multiple sources, fuses the data elements, and distributes the information through va...

KSC-99pp0670

NASA Image and Video Library

1999-06-12

In Hangar AE, Cape Canaveral Air Station (CCAS), NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite stands ready to be moved to the launch pad. The black rectangle on top is the optical port; at the lower edge are the radiators. The total length of the instrument is approximately four meters. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. Launch is targeted for June 23 from Launch Pad 17A, CCAS, aboard a Boeing Delta II rocket

An extended framework for science.

PubMed

Cazalis, Roland

2017-12-01

We may be at the cusp of a next generation framework for science which can be facilitated by understanding current limitations in the context of a divergence of 'scientific' tradition from the Axial Age (800-200 BCE) to the present. A powerful advance may come from fusing certain elements from Western and Eastern traditions, synthesizing the framework with an apt understanding of the divergence. Key traits will include the ethopoetic nature of the scientist with attention to his/her experience of self. The framework will also 'access' knowledge through a state of mind less encumbered with paradoxes, duality, incompatibility and other aporias. Case studies in biology and physics illustrate possibilities. Copyright © 2017 Elsevier Ltd. All rights reserved.

Laser-ablation ICP-MS as a tool for whole rock trace element analyses on fused powders

NASA Astrophysics Data System (ADS)

Girard, G.; Rooney, T. O.

2013-12-01

Here we present an accurate and precise technique for routine trace element analysis of geologic materials by laser-ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). We focus on rock powders previously prepared for X-ray fluorescence by fusion in a Li2B4O7 flux, and subsequently quenched in a Pt mold to form a glass disk. Our method allows for the analysis up to 30 trace elements by LA-ICP-MS using a Photon-Machines Analyte G2 193 nm excimer laser coupled to a Thermo-Fisher Scientific ICAP Q quadrupole ICP-MS. Analyses are run as scans on the surface of the disks. Laser ablation conditions for which trace element fractionation effects are minimal have been empirically determined to be ~ 4 J m-2 fluence, at 10 Hz , and 10 μm s-1 scan speed, using a 110 μm laser beam size. Ablated material is carried into the ICP-MS by a He carrier at a rate of 0.75 L min-1. Following pre-ablation to remove surface particles, samples are ablated for 200 s, of which 140 s are used for data acquisition. At the end of each scan, a gas blank is collected for 30 s. Dwell times for each element vary between 15 and 60 μs, depending on abundance and instrument sensitivity, allowing 120 readings of each element during the data acquisition time window. To correct for variations in the total volume of material extracted by the laser, three internal standards are used, Ca, Fe and Zr. These elements are routinely analyzed by X-ray fluorescence by the Geoanalytical laboratory at Michigan State University with precision and accuracy of <5%. The availability of several internal standards allows for better correction of possible persisting laser ablation fractionation effects; for a particular trace element, we correct using the internal standard that best reproduces its ablation behavior. Our calibration is based on a combination of fused powders of US Geological Survey and Geological Survey of Japan rock standards, NIST SRM 612 glass, and US Geological Survey natural and synthetic basalt glasses. Instrumental drift is monitored during each run using two fused standards analyzed multiple times as unknowns. We routinely achieve an external precision of <5% on multiple replicates of standards run as unknowns, which are also within <5% of certified values. Elements analyzed include most first row transition metals, large ion lithophile elements, high field strength elements, lanthanide and actinide rare earth elements.

KSC-99padig001

NASA Image and Video Library

1999-06-24

The shadow of a photographer (right) is caught watching the perfect launch of the Boeing Delta II rocket in the background after it lifted off at 11:44 a.m. EDT. The rocket carries NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite, which was developed to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

A CPS Based Optimal Operational Control System for Fused Magnesium Furnace

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chai, Tian-you; Wu, Zhi-wei; Wang, Hong

Fused magnesia smelting for fused magnesium furnace (FMF) is an energy intensive process with high temperature and comprehensive complexities. Its operational index namely energy consumption per ton (ECPT) is defined as the consumed electrical energy per ton of acceptable quality and is difficult to measure online. Moreover, the dynamics of ECPT cannot be precisely modelled mathematically. The model parameters of the three-phase currents of the electrodes such as the molten pool level, its variation rate and resistance are uncertain and nonlinear functions of the changes in both the smelting process and the raw materials composition. In this paper, an integratedmore » optimal operational control algorithm proposed is composed of a current set-point control, a current switching control and a self-optimized tuning mechanism. The tight conjoining of and coordination between the computational resources including the integrated optimal operational control, embedded software, industrial cloud, wireless communication and the physical resources of FMF constitutes a cyber-physical system (CPS) based embedded optimal operational control system. Successful application of this system has been made for a production line with ten fused magnesium furnaces in a factory in China, leading to a significant reduced ECPT.« less

5. CONSTRUCTION PROGRESS VIEW OF ASSEMBLY USED TO RAISE AND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. CONSTRUCTION PROGRESS VIEW OF ASSEMBLY USED TO RAISE AND LOWER FUEL ELEMENTS. TAKEN FROM TOP OF SHIELDING TANK WITH CAMERA POINTING TOWARDS BOTTOM OF TANK. SHOWS LADDER, SQUARE LIFTING FRAME, FUEL ELEMENT HOLDERS, AND CABLE CYLINDERS. INEL PHOTO NUMBER 65-5434, TAKEN OCTOBER 20, 1965. - Idaho National Engineering Laboratory, Advanced Reentry Vehicle Fusing System, Scoville, Butte County, ID

30 CFR 28.1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-07-01

... PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR TRAILING CABLES IN... trailing cables in coal mines, or the approval of changes or modifications of approved fuses; (b) to...-circuit protection for trailing cables in coal mines; and (c) to provide for the issuance of certificates...

KSC-99pp0669

NASA Image and Video Library

1999-06-12

Standing in Hangar AE, Cape Canaveral Air Station (CCAS) is NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. The black rectangle on top is the optical port; at the lower right is the solar panel; behind (left) the lower edge of the panel are the radiators. The total length of the instrument is approximately four meters. FUSE was developed by The Johns Hopkins University under contract to Goddard Space Flight Center, Greenbelt, Md., to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum. Launch is targeted for June 23 from Launch Pad 17A, CCAS, aboard a Boeing Delta II rocket

HVI Ballistic Limit Characterization of Fused Silica Thermal Panes

NASA Technical Reports Server (NTRS)

Miller, J. E.; Bohl, W. D.; Christiansen, E. L.; Davis, B. A.; Deighton, K. D.

2015-01-01

Fused silica window systems are used heavily on crewed reentry vehicles, and they are currently being used on the next generation of US crewed spacecraft, Orion. These systems improve crew situational awareness and comfort, as well as, insulating the reentry critical components of a spacecraft against the intense thermal environments of atmospheric reentry. Additionally, these materials are highly exposed to space environment hazards like solid particle impacts. This paper discusses impact studies up to 10 km/s on a fused silica window system proposed for the Orion spacecraft. A ballistic limit equation that describes the threshold of perforation of a fuse silica pane over a broad range of impact velocities, obliquities and projectile materials is discussed here.

The Nova-Dwarf Nova Connection

NASA Astrophysics Data System (ADS)

De Marco, Orsola

The extraordinary discovery that thermonuclear runaway (TNR) processed material lives on the white dwarf (WD) surface in the dwarf nova (DN) system VW Hyi is in direct conflict with the currently accepted model for DNe. The WD in VW Hyi should be continuously buried in solar-abundance material accreted from its fully-convective, low-mass main sequence companion. IT ISNT. There are either subtle metallicity-varying forces at work, or the current theory of DNe is completely wrong. Only by monitoring the abundances of key elements throughout an entire dwarf nova cycle will we be able to observe the rate of change of key abundance ratios by accretion and mixing processes, and hence deduce the relative importance of diffusion (in removing metals), accretion (in adding metals) and (non-party line but possible) local nuclear burning. FUSE is ideal for this task, because its spectral range contains key lines of important elements, because of its high temperature sensitivity and because in its wavelength range, the VW Hyi spectrum is totally dominated by the WD. VW Hyi is the obvious candidate for this project, because we already know that its abundances are indicative of recent TNR processing.

Thermal analysis of fused deposition modeling process using infrared thermography imaging and finite element modeling

NASA Astrophysics Data System (ADS)

Zhou, Xunfei; Hsieh, Sheng-Jen

2017-05-01

After years of development, Fused Deposition Modeling (FDM) has become the most popular technique in commercial 3D printing due to its cost effectiveness and easy-to-operate fabrication process. Mechanical strength and dimensional accuracy are two of the most important factors for reliability of FDM products. However, the solid-liquid-solid state changes of material in the FDM process make it difficult to monitor and model. In this paper, an experimental model was developed to apply cost-effective infrared thermography imaging method to acquire temperature history of filaments at the interface and their corresponding cooling mechanism. A three-dimensional finite element model was constructed to simulate the same process using element "birth and death" feature and validated with the thermal response from the experimental model. In 6 of 9 experimental conditions, a maximum of 13% difference existed between the experimental and numerical models. This work suggests that numerical modeling of FDM process is reliable and can facilitate better understanding of bead spreading and road-to-road bonding mechanics during fabrication.

FUSE Observations of He-rich sdB Stars

NASA Technical Reports Server (NTRS)

Swiegart, A. V.; Lanz, T.; Brown, T. M.; Hubeny, I.; Landsman, W. B.

2003-01-01

Most subdwarf B stars are extremely deficient in helium and selected light elements, but a minority are helium-rich. New evolutionary calculations suggest that these helium-rich sdB stars are the result of a delayed helium-core flash on the white dwarf cooling curve, which leads to extensive mixing between the hydrogen envelope and helium core. Such mixed stars should show greatly enhanced helium and carbon with respect to the other heavy elements. We have recently obtained FUSE spectra of two helium-rich sdB stars, PG1544+488 and JL87, revealing huge C Ill lines at 977 and 1176 A. Our analysis shows that PG1544+488 has a surface composition of 97% He, 2% C, and 1% N, in agreement with the new evolutionary scenario. While JL87 also reveals a large enrichment in carbon and nitrogen (1.4% and 0.4%, respectively), there is still a significant amount of hydrogen in its atmosphere.

Influence of subsurface defects on damage performance of fused silica in ultraviolet laser

NASA Astrophysics Data System (ADS)

Huang, Jin; Zhou, Xinda; Liu, Hongjie; Wang, Fengrui; Jiang, Xiaodong; Wu, Weidong; Tang, Yongjian; Zheng, Wanguo

2013-02-01

In ultraviolet pulse laser, damage performance of fused silica optics is directly dependent on the absorptive impurities and scratches in subsurface, which are induced by mechanical polishing. In the research about influence of subsurface defects on damage performance, a series of fused silica surfaces with various impurity concentrations and scratch structures were created by hydrofluoric (HF) acid solution etching. Time of Flight secondary ion mass spectrometry and scanning probe microprobe revealed that with increasing etching depth, impurity concentrations in subsurface layers are decreased, the scratch structures become smoother and the diameter:depth ratio is increased. Damage performance test with 355-nm pulse laser showed that when 600 nm subsurface thickness is removed by HF acid etching, laser-induced damage threshold of fused silica is raised by 40 percent and damage density is decreased by over one order of magnitude. Laser weak absorption was tested to explain the cause of impurity elements impacting damage performance, field enhancement caused by change of scratch structures was calculated by finite difference time domain simulation, and the calculated results are in accord with the damage test results.

Wideband two-port beam splitter of a binary fused-silica phase grating.

PubMed

Wang, Bo; Zhou, Changhe; Feng, Jijun; Ru, Huayi; Zheng, Jiangjun

2008-08-01

The usual beam splitter of multilayer-coated film with a wideband spectrum is not easy to achieve. We describe the realization of a wideband transmission two-port beam splitter based on a binary fused-silica phase grating. To achieve high efficiency and equality in the diffracted 0th and -1st orders, the grating profile parameters are optimized using rigorous coupled-wave analysis at a wavelength of 1550 nm. Holographic recording and the inductively coupled plasma dry etching technique are used to fabricate the fused-silica beam splitter grating. The measured efficiency of (45% x 2) = 90% diffracted into the both orders can be obtained with the fabricated grating under Littrow mounting. The physical mechanism of such a wideband two-port beam splitter grating can be well explained by the modal method based on two-beam interference of the modes excited by the incident wave. With the high damage threshold, low coefficient of thermal expansion, and wideband high efficiency, the presented beam splitter etched in fused silica should be a useful optical element for a variety of practical applications.

Does disc space height of fused segment affect adjacent degeneration in ALIF? A finite element study.

PubMed

Tang, Shujie; Meng, Xueying

2011-01-01

The restoration of disc space height of fused segment is essential in anterior lumbar interbody fusion, while the disc space height in many cases decreased postoperatively, which may adversely aggravate the adjacent segmental degeneration. However, no literature available focused on the issue. A normal healthy finite element model of L3-5 and four anterior lumbar interbody fusion models with different disc space height of fused segment were developed. 800 N compressive loading plus 10 Nm moments simulating flexion, extension, lateral bending and axial rotation were imposed on L3 superior endplate. The intradiscal pressure, the intersegmental rotation, the tresca stress and contact force of facet joints in L3-4 were investigated. Anterior lumbar interbody fusion with severely decreased disc space height presented with the highest values of the four parameters, and the normal healthy model presented with the lowest values except, under extension, the contact force of facet joints in normal healthy model is higher than that in normal anterior lumbar interbody fusion model. With disc space height decrease, the values of parameters in each anterior lumbar interbody fusion model increase gradually. Anterior lumbar interbody fusion with decreased disc space height aggravate the adjacent segmental degeneration more adversely.

Advanced Thermoplastic Polymers and Additive Manufacturing Applied to ISS Columbus Toolbox: Lessons Learnt and Results

NASA Astrophysics Data System (ADS)

Ferrino, Marinella; Secondo, Ottaviano; Sabbagh, Amir; Della Sala, Emilio

2014-06-01

In the frame of the International Space Station (ISS) Exploitation Program a new toolbox has been realized by TAS-I to accommodate the tools currently in use on the ISS Columbus Module utilizing full-scale prototypes obtained with 3D rapid prototyping. The manufacturing of the flight hardware by means of advanced thermoplastic polymer UL TEM 9085 and additive manufacturing Fused Deposition Modelling (FDM) technology represent innovative elements. In this paper, the results achieved and the lessons learned are analyzed to promote future technology know-how. The acquired experience confirmed that the additive manufacturing process allows to save time/cost and to realize new shapes/features to introduce innovation in products and future design processes for space applications.

Research on laser-induced damage resistance of fused silica optics by the fluid jet polishing method.

PubMed

Lv, Liang; Ma, Ping; Huang, Jinyong; He, Xiang; Cai, Chao; Zhu, Heng

2016-03-20

Laser-induced damage threshold (LIDT) is one important evaluation index for optical glasses applied in large laser instruments which are exposed to high light irradiation flux. As a new kind of precise polishing technology, fluid jet polishing (FJP) has been widely used in generating planar, spherical, and aspherical optics with high-accuracy surfaces. Laser damage resistances of fused silica optics by the FJP process are studied in this paper. Fused silica samples with various FJP parameters are prepared, and laser damage experiments are performed with 351 nm wavelength and a 5.5 ns pulse width laser. Experimental results demonstrate that the LIDT of the samples treated with FJP processes did not increase, compared to their original state. The surface quality of the samples is one factor for the decrease of LIDT. For ceria solution polished samples, the cerium element remaining is another factor of the lower LIDT.

Finite element analysis of stresses in Berkovich, Vickers and Knoop indentation for densifying and non-densifying glasses

NASA Astrophysics Data System (ADS)

Chen, Kanghua

2002-08-01

A constitutive law for fused silica accounting for its permanent densification under large compressive stresses is presented. The implementation of the constitutive equations in the general-purpose finite element code ABAQUS via user subroutine is proposed and carefully verified. The three-dimensional indentation mechanics under Berkovich, Vickers and Knoop indenters is extensively investigated based on the proposed constitutive relation. The results of stress distribution and plastic zone for both densifying and non-densifying optical glasses are systematically compared. These numerical results are in good agreement with the experimental observations of optical manufacturing. That is, fused silica shows lower material removal rate, smaller surface roughness and subsurface damage in contrast to non-densifying optical glasses under the same grinding condition. Material densification of fused silica is thoroughly studied through numerical simulations of indentation mechanics. The exact amount of densification and shear strain of fused silica under Berkovich indentation is calculated to show the deformation mechanism of glass materials under three-dimensional indentations. The surface profiles show the material "pile-up" around the indenter tip for non-densifying glasses and "sink-in" for fused silica after the indentation load is removed. An important inverse problem is studied: estimation of abrasive size and indentation load through the examination of residual indentation footprints. A series of 2D axisymmetric spherical indentation simulations generate a wide range of relationships among the indentation load, indenter size, residual indentation depth and size of residual indentation zone for the five selected brittle materials: glass fused silica (FS), BK7, semiconductor Si, laser glass LHG8, and optical crystal CaF2.. The application of the inverse problem is verified by the good agreement between the estimated abrasive size and the actual abrasive size found during a material removal experiment of magnetorheological finishing (MRF) of fused silica. The explanation of indentation size effect (ISE) is attempted using numerical indentation simulations. Vickers indentation simulations on the five selected brittle materials (FS, BK7, Si, LHG8 and CaF2.) show no size dependence of Vickers hardness when the material is modeled as elastic-perfectly plastic (with or without densification). The simulation results on axisymmetric conical indentation also indicate that the bluntness of the indenter tip is not the reason for the indentation size effect. A new constitutive model accounting for the material length scale is needed in order to explain the well-observed indentation size effect during indentation tests.

Chromodomains direct integration of retrotransposons to heterochromatin

PubMed Central

Gao, Xiang; Hou, Yi; Ebina, Hirotaka; Levin, Henry L.; Voytas, Daniel F.

2008-01-01

The enrichment of mobile genetic elements in heterochromatin may be due, in part, to targeted integration. The chromoviruses are Ty3/gypsy retrotransposons with chromodomains at their integrase C termini. Chromodomains are logical determinants for targeting to heterochromatin, because the chromodomain of heterochromatin protein 1 (HP1) typically recognizes histone H3 K9 methylation, an epigenetic mark characteristic of heterochromatin. We describe three groups of chromoviruses based on amino acid sequence relationships of their integrase C termini. Genome sequence analysis indicates that representative chromoviruses from each group are enriched in gene-poor regions of the genome relative to other retrotransposons, and when fused to fluorescent marker proteins, the chromodomains target proteins to specific subnuclear foci coincident with heterochromatin. The chromodomain of the fungal element, MAGGY, interacts with histone H3 dimethyl- and trimethyl-K9, and when the MAGGY chromodomain is fused to integrase of the Schizosaccharomyces pombe Tf1 retrotransposon, new Tf1 insertions are directed to sites of H3 K9 methylation. Repetitive sequences such as transposable elements trigger the RNAi pathway resulting in their epigenetic modification. Our results suggest a dynamic interplay between retrotransposons and heterochromatin, wherein mobile elements recognize heterochromatin at the time of integration and then perpetuate the heterochromatic mark by triggering epigenetic modification. PMID:18256242

The SAGES Fundamental Use of Surgical Energy program (FUSE): history, development, and purpose.

PubMed

Fuchshuber, P; Schwaitzberg, S; Jones, D; Jones, S B; Feldman, L; Munro, M; Robinson, T; Purcell-Jackson, G; Mikami, D; Madani, A; Brunt, M; Dunkin, B; Gugliemi, C; Groah, L; Lim, R; Mischna, J; Voyles, C R

2018-06-01

Adverse events due to energy device use in surgical operating rooms are a daily occurrence. These occur at a rate of approximately 1-2 per 1000 operations. Hundreds of operating room fires occur each year in the United States, some causing severe injury and even mortality. The Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) therefore created the first comprehensive educational curriculum on the safe use of surgical energy devices, called Fundamental Use of Surgical Energy (FUSE). This paper describes the history, development, and purpose of this important training program for all members of the operating room team. The databases of SAGES and the FUSE committee as well as personal photographs and documents of members of the FUSE task force were used to establish a brief history of the FUSE program from its inception to its current status. The authors were able to detail all aspects of the history, development, and national as well as global implementation of the third SAGES Fundamentals Program FUSE. The written documentation of the making of FUSE is an important contribution to the history and mission of SAGES and allows the reader to understand the idea, concept, realization, and implementation of the only free online educational tool for physicians on energy devices available today. FUSE is the culmination of the SAGES efforts to recognize gaps in patient safety and develop state-of-the-art educational programs to address those gaps. It is the goal of the FUSE task force to ensure that general FUSE implementation becomes multinational, involving as many countries as possible.

Efficient low static-volume water heater

NASA Technical Reports Server (NTRS)

Brown, R. L.

1976-01-01

Calrod heating element is surrounded by matrix of fused sintered copper or brass balls, and assembly is then installed in piping of water system. As water flows through matrix, sintered balls cause turbulent flow and heating. Applications include laundromats, laboratories, and photographic labs.

A prototype hybrid 7π quinone-fused 1,3,2-dithiazolyl radical.

PubMed

Decken, A; Mailman, A; Passmore, J; Rautiainen, J M; Scherer, W; Scheidt, E-W

2011-01-28

Reaction of 1,4-naphthoquinone and SNSMF(6) (M = As, Sb) in SO(2) solution in a 1 : 2 molar ratio led to the naphthoquinone fused 1,3,2-dithiazolylium salts, 3MF(6) quantitatively by multinuclear NMR (87% isolated yield of 3SbF(6)) via the cycloaddition and oxidative dehydrogenation chemistry of SNS(+) with formation of NH(4)SbF(6) and S(8). The product 3SbF(6) was fully characterized by IR, Raman, multinuclear {(1)H, (13)C, (14)N} NMR, elemental analysis, cyclic voltammetry and single crystal X-ray crystallography. The reduction of 3SbF(6) with ferrocene (Cp(2)Fe) in refluxing acetonitrile (CH(3)CN) led to the first isolation of a fused quinone-thiazyl radical, 3˙ in 73% yield. The prototype hybrid quinone-thiazyl radical 3˙ was fully characterized by IR, Raman microscopy, EI-MS, elemental analysis, solution and solid state EPR, magnetic susceptibility (2-370 K) and was found to form π*-π* dimers in the solid state as determined by single crystal X-ray crystallography. Furthermore, the thermal decomposition of 3˙ led to a novel quinone-fused 1,2,3,4-tetrathiine, 10 (x = 2) and the known 1,2,5-thiadiazole, 11. The energetics of the cycloadditon and oxidative dehydrogenation chemistry of SNS(+) and 1,4-naphthoquinone leading to 3SbF(6) were estimated in the gas phase and SO(2) solution by DFT calculations (PBE0/6-311G(d)) and lattice enthalpies obtained by the volume based thermodynamic (VBT) approach in the solid state. The gas phase ion energetics (ionization potential (IP) and electron affinity (EA)) of 3˙ are compared to related 1,3,2- and 1,2,3-dithiazolyl radicals.

Additive manufacturing of glass for optical applications

NASA Astrophysics Data System (ADS)

Luo, Junjie; Gilbert, Luke J.; Bristow, Douglas A.; Landers, Robert G.; Goldstein, Jonathan T.; Urbas, Augustine M.; Kinzel, Edward C.

2016-04-01

Glasses including fused quartz have significant scientific and engineering applications including optics, communications, electronics, and hermetic seals. This paper investigates a filament fed process for Additive Manufacturing (AM) of fused quartz. Additive manufacturing has several potential benefits including increased design freedom, faster prototyping, and lower processing costs for small production volumes. However, current research in AM of glasses is limited and has focused on non-optical applications. Fused quartz is studied here because of its desirability for high-quality optics due to its high transmissivity and thermal stability. Fused quartz also has a higher working temperature than soda lime glass which poses a challenge for AM. In this work, fused quartz filaments are fed into a CO2 laser generated melt pool, smoothly depositing material onto the work piece. Single tracks are printed to explore the effects that different process parameters have on the morphology of printed fused quartz. A spectrometer is used to measure the thermal radiation incandescently emitted from the melt pool. Thin-walls are printed to study the effects of layer-to-layer height. Finally, a 3D fused quartz cube is printed using the newly acquired layer height and polished on each surface. The transmittance and index homogeneity of the polished cube are both measured. These results show that the filament fed process has the potential to print fused quartz with optical transparency and of index of refraction uniformity approaching bulk processed glass.

Determination of major elements by wavelength-dispersive X-ray fluorescence spectrometry and trace elements by inductively coupled plasma mass spectrometry in igneous rocks from the same fused sample (110 mg)

NASA Astrophysics Data System (ADS)

Amosova, Alena A.; Panteeva, Svetlana V.; Chubarov, Victor M.; Finkelshtein, Alexandr L.

2016-08-01

The fusion technique is proposed for simultaneous determination of 35 elements from the same sample. Only 110 mg of rock sample was used to obtain fused glasses for quantitative determination of 10 major elements by wavelength dispersive X-ray fluorescence analysis, 16 rare earth elements and some other trace elements by inductively coupled plasma mass spectrometry analysis. Fusion was performed with 1.1 g of lithium metaborate and LiBr solution as the releasing agent in platinum crucible in electric furnace at 1100 °C. The certified reference materials of ultramafic, mafic, intermediate and felsic igneous rocks have been applied to obtain the calibration curves for rock-forming oxides (Na2O, MgO, Al2O3, SiO2, P2O5, K2O, CaO, TiO2, MnO, Fe2O3) and some trace elements (Ba, Sr, Zr) determination by X-ray fluorescence analysis. The repeatability does not exceed the allowable standard deviation for a wide range of concentrations. In the most cases the relative standard deviation was less than 5%. Obtained glasses were utilized for the further determination of rare earth (La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu) and some other (Ba, Sr, Zr, Rb, Cs, Y, Nb, Hf, Ta, Th and U) trace elements by inductively coupled plasma mass spectrometry analysis with the same certified reference materials employed. The results could mostly be accepted as satisfactory. The proposed procedure essentially reduces the expenses in comparison with separate sample preparation for inductively coupled plasma mass spectrometry and X-ray fluorescence analysis.

TARDEC FMEA TRAINING: Understanding and Evaluating Failure Mode and Effects Analyses (FMEA)

DTIC Science & Technology

2012-06-07

Tip Brass 1 1.1.2.1.3 Ball Tungsten Carbide 1 1.1.2.1.4 Blue Ink Ink .1 grams 1.1.2.2 Steel 1 1.1.3 ABS/PP 1 Ink/Spring Assembly Ink Tube Spring Nib...does not meet airflow (8) voltage circuit analy sis of vehic le - New Yuma - test requirements (6 in. WCtJ.P -Blown fuse control c ircuit vehicle...1500 CFM for XXXX) - Broken wire - Compare fuse capacity to in-rush current and stall current during high ambient temperature conditions - Review

On Fusing Recursive Traversals of K-d Trees

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rajbhandari, Samyam; Kim, Jinsung; Krishnamoorthy, Sriram

Loop fusion is a key program transformation for data locality optimization that is implemented in production compilers. But optimizing compilers currently cannot exploit fusion opportunities across a set of recursive tree traversal computations with producer-consumer relationships. In this paper, we develop a compile-time approach to dependence characterization and program transformation to enable fusion across recursively specified traversals over k-ary trees. We present the FuseT source-to-source code transformation framework to automatically generate fused composite recursive operators from an input program containing a sequence of primitive recursive operators. We use our framework to implement fused operators for MADNESS, Multiresolution Adaptive Numerical Environmentmore » for Scientific Simulation. We show that locality optimization through fusion can offer more than an order of magnitude performance improvement.« less

KSC-99padig002

NASA Image and Video Library

1999-06-24

KENNEDY SPACE CENTER, FLA. -- A fireball erupts under the Boeing Delta II rocket, amid clouds of smoke and steam, as it lifts off from Launch Pad 17A, Cape Canaveral Air Station, at 11:44 a.m. EDT. The shadow of a photographer (right) is caught watching the perfect launch. The rocket carries NASA's Far Ultraviolet Spectroscopic Explorer (FUSE) satellite, which was developed to investigate the origin and evolution of the lightest elements in the universe hydrogen and deuterium. In addition, the FUSE satellite will examine the forces and process involved in the evolution of the galaxies, stars and planetary systems by investigating light in the far ultraviolet portion of the electromagnetic spectrum

A Qualitative Experiment: Research on Mediated Meaning Construction Using a Hybrid Approach

ERIC Educational Resources Information Center

Robinson, Sue; Mendelson, Andrew L.

2012-01-01

This article presents a hybrid methodological technique that fuses elements of experimental design with qualitative strategies to explore mediated communication. Called the "qualitative experiment," this strategy uses focus groups and in-depth interviews "within" randomized stimulus conditions typically associated with…

A Computational Procedure for the Protection of Industrial Power Systems.

DTIC Science & Technology

1981-11-01

Sumary ................................. ... 79 9 . CONCLUSIONS ....... ..................... ... 80 Recomnendations for Further Work ... ........... ... 81...34- - : "’< ’"’-......................"..-..-..--......-..... 9 Fuses. Two types of fuses are used in the coordination pro- gram. These are current-limiting and...NUMONICS Electronic Graphics Calculator [ 9 ]. The NUMONICS EGC then provided a convenient way to enter X-Y coordinate data representing any curve onto disk

Heavy Element Abundances in Two B0-B0.5 Main Sequence Stars in the Small Magellanic Cloud

NASA Astrophysics Data System (ADS)

Peters, Geraldine J.

We propose FUSE observations of AV304 (B0.5V) and NGC346-637 B0V), two sharp-lined main-sequence stars in the Small Magellanic Cloud, to determine the abundances of heavy elements, especially those of the iron group. The FUSE spectral region contains numerous Fe III lines, including the resonance multiplet (UV 1) near 1130 Angstroms, that is excellent for abundance determinations and two strong multiplets of V III, an ion that does not produce measurable lines longward of 1200 Angstoms, in metal-deficient stars. In addition there are several measurable lines from Cr III and Mn III. A limited analyses of ground-based spectra of these stars by Dufton et al. (1990) and Rolleston et al. (1993) indicated an average underabundance of 0.7-0.8 dex for most light elements and a recent analysis of HSTSTIS data on AV304 by Peters & Grigsby (2001) suggests that the Fe group elements are depleted by the same amount relative to the sun. When combined with the HST-STIS results, this effort will represent the first attempt to measure the abundances of Fe group elements in the photospheres of early B, main sequence stars in an external galaxy. Although abundances of the Fe-peak elements are of interest because they are important for assessing opacities for stellar evolution calculations and the validity of theoretical calculations of explosive nucleosynthesis, the ground-based study did not yield this information because measurable lines from these species are found only in the UV spectral region. Abundances and abundance ratios of both heavy & light elements will be compared with the HST-STIS results from AV304, H II regions, supernova remnants, evolved massive stars in the SMC, and theoretical calculations of nucleosynthesis.

Additive manufacturing of transparent fused quartz

NASA Astrophysics Data System (ADS)

Luo, Junjie; Hostetler, John M.; Gilbert, Luke; Goldstein, Jonathan T.; Urbas, Augustine M.; Bristow, Douglas A.; Landers, Robert G.; Kinzel, Edward C.

2018-04-01

This paper investigates a filament-fed process for additive manufacturing (AM) of fused quartz. Glasses such as fused quartz have significant scientific and engineering applications, which include optics, communications, electronics, and hermetic seals. AM has several attractive benefits such as increased design freedom, faster prototyping, and lower processing costs for small production volumes. However, current research into glass AM has focused primarily on nonoptical applications. Fused quartz is studied here because of its desirability for use in high-quality optics due to its high transmissivity and thermal stability. Fused quartz filaments are fed into a CO2 laser-generated molten region, smoothly depositing material onto the workpiece. Spectroscopy and pyrometry are used to measure the thermal radiation incandescently emitted from the molten region. The effects of the laser power and scan speed are determined by measuring the morphology of single tracks. Thin walls are printed to study the effects of layer-to-layer height. This information is used to deposit solid pieces including a cylindrical-convex shape capable of focusing visible light. The transmittance and index homogeneity of the printed fused quartz are measured. These results show that the filament-fed process has the potential to print transmissive optics.

High-performance fused indium gallium arsenide/silicon photodiode

NASA Astrophysics Data System (ADS)

Kang, Yimin

Modern long haul, high bit rate fiber-optic communication systems demand photodetectors with high sensitivity. Avalanche photodiodes (APDs) exhibit superior sensitivity performance than other types of photodetectors by virtual of its internal gain mechanism. This dissertation work further advances the APD performance by applying a novel materials integration technique. It is the first successful demonstration of wafer fused InGaAs/Si APDs with low dark current and low noise. APDs generally adopt separate absorption and multiplication (SAM) structure, which allows independent optimization of materials properties in two distinct regions. While the absorption material needs to have high absorption coefficient in the target wavelength range to achieve high quantum efficiency, it is desirable for the multiplication material to have large discrepancy between its electron and hole ionization coefficients to reduce noise. According to these criteria, InGaAs and Si are the ideal materials combination. Wafer fusion is the enabling technique that makes this theoretical ideal an experimental possibility. APDs fabricated on the fused InGaAs/Si wafer with mesa structure exhibit low dark current and low noise. Special device fabrication techniques and high quality wafer fusion reduce dark current to nano ampere level at unity gain, comparable to state-of-the-art commercial III/V APDs. The small excess noise is attributed to the large difference in ionization coefficients between electrons and holes in silicon. Detailed layer structure designs are developed specifically for fused InGaAs/Si APDs based on principles similar to those used in traditional InGaAs/InP APDs. An accurate yet straightforward technique for device structural parameters extraction is also proposed. The extracted results from the fabricated APDs agree with device design parameters. This agreement also confirms that the fusion interface has negligible effect on electric field distributions for devices fabricated from high quality fusion materials. The feasibility of fused InGaAs/Si APD for analog systems is also explored. Preliminary two-tone measurement shows that a moderately high dynamic range of 70 dBc/Hz1/2 for broadband Spur Free Dynamic Range (SFDR) or 82 dBc/Hz2/3 suboctave SFDR, up to 50 muA of optical current, can be achieved. The theoretical analyses of SNR show that fused InGaAs/Si APD receivers can provide larger Signal-to-Noise Ratio (SNR) than their III/V counterparts.

30 CFR 28.4 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR TRAILING... provides short-circuit protection for trailing cables in coal mines by interrupting an excessive current in...

Solar concentrator protective system

NASA Technical Reports Server (NTRS)

Selcuk, M. K. (Inventor)

1984-01-01

A mechanism that blocks concentrated sunlight from reaching a receiver, in the event of a tracking failure or loss of coolant is described. Sunlight is normally concentrated by a dish reflector onto the opening of a receiver. A faceplate surrounds the opening, and coolant carrying tubes, line the receiver. If the concentrated sunlight wanders so it begins to fall on the faceplate, then the sunlight will melt a portion of a fuse wire portion will break. The wire is attached to a flange on a shutter frame, and breaking of the fuse wire allows the frame to fall. Normally, the shutter frame supports shutter elements that are held open by cam followers that bear against cams.

Fuse protects circuit from voltage and current overloads

NASA Technical Reports Server (NTRS)

Casey, L. O.

1969-01-01

Low-melting resistor connected in series with the load protects the circuit against current overloads. It protects test subjects and patients being monitored by electronic instrumentation from inadvertant overloads of current, and sensitive electronic equipment against high-voltage damage.

Integral Battery Power Limiting Circuit for Intrinsically Safe Applications

NASA Technical Reports Server (NTRS)

Burns, Bradley M.; Blalock, Norman N.

2010-01-01

A circuit topology has been designed to guarantee the output of intrinsically safe power for the operation of electrical devices in a hazardous environment. This design uses a MOSFET (metal oxide semiconductor field-effect transistor) as a switch to connect and disconnect power to a load. A test current is provided through a separate path to the load for monitoring by a comparator against a preset threshold level. The circuit is configured so that the test current will detect a fault in the load and open the switch before the main current can respond. The main current passes through the switch and then an inductor. When a fault occurs in the load, the current through the inductor cannot change immediately, but the voltage drops immediately to safe levels. The comparator detects this drop and opens the switch before the current in the inductor has a chance to respond. This circuit protects both the current and voltage from exceeding safe levels. Typically, this type of protection is accomplished by a fuse or a circuit breaker, but in order for a fuse or a circuit breaker to blow or trip, the current must exceed the safe levels momentarily, which may be just enough time to ignite anything in a hazardous environment. To prevent this from happening, a fuse is typically current-limited by the addition of the resistor to keep the current within safe levels while the fuse reacts. The use of a resistor is acceptable for non-battery applications where the wasted energy and voltage drop across the resistor can be tolerated. The use of the switch and inductor minimizes the wasted energy. For example, a circuit runs from a 3.6-V battery that must be current-limited to 200 mA. If the circuit normally draws 10 mA, then an 18-ohm resistor would drop 180 mV during normal operation, while a typical switch (0.02 ohm) and inductor (0.97 ohm) would only drop 9.9 mV. From a power standpoint, the current-limiting resistor protection circuit wastes about 18 times more power than the switch and the inductor configuration. In the fault condition, both the resistor and the inductor react immediately. The resistor reacts by allowing more current to flow and dropping the voltage. Initially, the inductor reacts by dropping the voltage, and then by not allowing the current to change. When the comparator detects the drop in voltage, it opens the switch, thus preventing any further current flow. The inductor alone is not sufficient protection, because after the voltage drop has settled, the inductor would then allow the current to change, in this example, the current would be 3.7 A. In the fault condition, the resistor is flowing 200 mA until the fuse blows (anywhere from 1 ms to 100 s), while the switch and inductor combination is flowing about 2 A test current while monitoring for the fault to be corrected. Finally, as an additional safety feature, the circuit can be configured to hold the switch opened until both the load and source are disconnected.

Infrared and visible image fusion based on robust principal component analysis and compressed sensing

NASA Astrophysics Data System (ADS)

Li, Jun; Song, Minghui; Peng, Yuanxi

2018-03-01

Current infrared and visible image fusion methods do not achieve adequate information extraction, i.e., they cannot extract the target information from infrared images while retaining the background information from visible images. Moreover, most of them have high complexity and are time-consuming. This paper proposes an efficient image fusion framework for infrared and visible images on the basis of robust principal component analysis (RPCA) and compressed sensing (CS). The novel framework consists of three phases. First, RPCA decomposition is applied to the infrared and visible images to obtain their sparse and low-rank components, which represent the salient features and background information of the images, respectively. Second, the sparse and low-rank coefficients are fused by different strategies. On the one hand, the measurements of the sparse coefficients are obtained by the random Gaussian matrix, and they are then fused by the standard deviation (SD) based fusion rule. Next, the fused sparse component is obtained by reconstructing the result of the fused measurement using the fast continuous linearized augmented Lagrangian algorithm (FCLALM). On the other hand, the low-rank coefficients are fused using the max-absolute rule. Subsequently, the fused image is superposed by the fused sparse and low-rank components. For comparison, several popular fusion algorithms are tested experimentally. By comparing the fused results subjectively and objectively, we find that the proposed framework can extract the infrared targets while retaining the background information in the visible images. Thus, it exhibits state-of-the-art performance in terms of both fusion effects and timeliness.

Evacuated FM08 Fuses Carry a Sustained Arc in a Bus over 75 VDC

NASA Technical Reports Server (NTRS)

Leidecker, Henning; Slonaker, J.

1999-01-01

The FM08 style fuse is specified to interrupt an overcurrent of up to 300 A in a bus of up to 125 VDC, but this applies only when its barrel is filled with air. When placed into a space-grade vacuum, the FM08 style fuse exhausts its air within a year. Then, the probability of an enduring arc is high for all ratings when the bus is above 75 VDC, and the overcurrent is large. The arc endures until something else interrupts the current. The fuse can violently eject metal vapor or other material during the sustained arcing. The evacuated FM08 does not develop a sustained arc when interrupted in a bus of 38 VDC or less, at least when there is little inductance in the circuit. This is consistent with its successful use in many spacecraft having buses in the range 24 to 36 volts.

UIT Observations of Early-Type Galaxies and Analysis of the FUSE Spectrum of a Subdwarf B Star

NASA Technical Reports Server (NTRS)

Ohl, Raymond G.; Krebs, Carolyn (Technical Monitor)

2001-01-01

This work covers Ultraviolet Imaging Telescope (UIT) observations of early-type galaxies (155 nm) and Far Ultraviolet Spectroscopic Explorer (FUSE) spectra of a Galactic subdwarf B star (sdB). Early UV space astronomy missions revealed that early-type galaxies harbor a population of stars with effective temperatures greater than that of the main sequence turn-off (about 6,000 K) and UV emission that is very sensitive to characteristics of the stellar population. We present UV (155 nm) surface photometry and UV-B color profiles for 8 E and SO galaxies observed by UIT. Some objects have de Vaucouleurs surface brightness profiles, while others have disk-like profiles, but we find no other evidence for the presence of a disk or young, massive stars. There is a wide range of UV-B color gradients, but there is no correlation with metallicity gradients. SdB stars are the leading candidate UV emitters in old, high metallicity stellar populations (e.g., early-type galaxies). We observed the Galactic sdB star PG0749+658 with FUSE and derived abundances with the aim of constraining models of the heavy element distribution in sdB atmospheres. All of the elements measured are depleted with respect to solar, except for Cr and Mn, which are about solar, and Ni, which is enhanced. This work was supported in part by NASA grants NAG5-700 and NAG5-6403 to the University of Virginia and NAS5-32985 to Johns Hopkins University.

46 CFR 28.365 - Overcurrent protection and switched circuits.

Code of Federal Regulations, 2011 CFR

2011-10-01

.... (c) Each ungrounded current carrying conductor must be protected in accordance with its current carrying capacity by a circuit breaker or fuse at the connection to the switchboard or distribution panel...

Ray tracing method for simulation of laser beam interaction with random packings of powders

NASA Astrophysics Data System (ADS)

Kovalev, O. B.; Kovaleva, I. O.; Belyaev, V. V.

2018-03-01

Selective laser sintering is a technology of rapid manufacturing of a free form that is created as a solid object by selectively fusing successive layers of powder using a laser. The motivation of this study is due to the currently insufficient understanding of the processes and phenomena of selective laser melting of powders whose time scales differ by orders of magnitude. To construct random packings from mono- and polydispersed solid spheres, the algorithm of their generation based on the discrete element method is used. A numerical method of ray tracing is proposed that is used to simulate the interaction of laser radiation with a random bulk packing of spherical particles and to predict the optical properties of the granular layer, the extinction and absorption coefficients, depending on the optical properties of a powder material.

FPGA-based fused smart-sensor for tool-wear area quantitative estimation in CNC machine inserts.

PubMed

Trejo-Hernandez, Miguel; Osornio-Rios, Roque Alfredo; de Jesus Romero-Troncoso, Rene; Rodriguez-Donate, Carlos; Dominguez-Gonzalez, Aurelio; Herrera-Ruiz, Gilberto

2010-01-01

Manufacturing processes are of great relevance nowadays, when there is a constant claim for better productivity with high quality at low cost. The contribution of this work is the development of a fused smart-sensor, based on FPGA to improve the online quantitative estimation of flank-wear area in CNC machine inserts from the information provided by two primary sensors: the monitoring current output of a servoamplifier, and a 3-axis accelerometer. Results from experimentation show that the fusion of both parameters makes it possible to obtain three times better accuracy when compared with the accuracy obtained from current and vibration signals, individually used.

Temperature Diffusion Distribution of Electric Wire Deteriorated by Overcurrent

NASA Astrophysics Data System (ADS)

Choi, Chung-Seog; Kim, Hyang-Kon; Kim, Dong-Woo; Lee, Ki-Yeon

This study presents thermal diffusion distribution of the electric wires when overcurrent is supplied to copper wires. And then, this study intends to provide a basis of knowledge for analyzing the causes of electric accidents through hybrid technology. In the thermal image distribution analysis of the electric wire to which fusing current was supplied, it was found that less heat was accumulated in the thin wires because of easier heat dispersion, while more heat was accumulated in the thicker wires. The 3-dimensional thermal image analysis showed that heat distribution was concentrated at the center of the wire and the inclination of heat distribution was steep in the thicker wires. When 81A was supplied to 1.6mm copper wire for 500 seconds, the surface temperature of wire was maximum 46.68°C and minimum 30.87°C. It revealed the initial characteristics of insulation deterioration that generates white smoke without external deformation. In the analysis with stereoscopic microscope, the surface turned dark brown and rough with the increase of fusing current. Also, it was known that exfoliation occurred when wire melted down with 2 times the fusing current. With the increase of current, we found the number of primary arms of the dendrite structure to be increased and those of the secondary and tertiary arms to be decreased. Also, when the overcurrent reached twice the fusing current, it was found that columnar composition, observed in the cross sectional structure of molten wire, appeared and formed regular directivity. As described above, we could present the burning pattern and change in characteristics of insulation and conductor quantitatively. And we could not only minimize the analysis error by combining the information but also present the scientific basis in the analysis of causes of electric accidents, mediation of disputes on product liability concerning the electric products.

46 CFR 28.860 - Overcurrent protection and switched circuits.

Code of Federal Regulations, 2010 CFR

2010-10-01

... current carrying conductor must be protected in accordance with its current carrying capacity by a circuit breaker or fuse at the connection to the switchboard or distribution panel bus. (d) Each circuit breaker...

46 CFR 28.860 - Overcurrent protection and switched circuits.

Code of Federal Regulations, 2011 CFR

2011-10-01

... current carrying conductor must be protected in accordance with its current carrying capacity by a circuit breaker or fuse at the connection to the switchboard or distribution panel bus. (d) Each circuit breaker...

The regulation of the SARK promoter activity by hormones and environmental signals.

PubMed

Delatorre, Carla A; Cohen, Yuval; Liu, Li; Peleg, Zvi; Blumwald, Eduardo

2012-09-01

The Senescence Associated Receptor Protein Kinase (P(SARK)) promoter, fused to isopentenyltransferase (IPT) gene has been shown to promote drought tolerance in crops. We dissected P(SARK) in order to understand the various elements associated with its activation and suppression. The activity of P(SARK) was higher in mature and early senescing leaves, and abiotic stress induced its activity in mature leaves. Bioinformatics analysis suggests the interactions of multiple cis-acting elements in the control of P(SARK) activity. In vitro gel shift assays and yeast one hybrid system revealed interactions of P(SARK) with transcription factors related to abscisic acid and cytokinin response. Deletion analysis of P(SARK), fused to GUS-reporter gene was used to identify specific regions regulating transcription under senescence or during drought stress. Effects of exogenous hormonal treatments were characterized in entire plants and in leaf disk assays, and regions responsive to various hormones were defined. Our results indicate a complex interaction of plant hormones and additional factors modulating P(SARK) activity under stress resulting in a transient induction of expression. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Judgment of Nasolabial Esthetics in Cleft Lip and Palate Is Not Influenced by Overall Facial Attractiveness.

PubMed

Kocher, Katharina; Kowalski, Piotr; Kolokitha, Olga-Elpis; Katsaros, Christos; Fudalej, Piotr S

2016-05-01

To determine whether judgment of nasolabial esthetics in cleft lip and palate (CLP) is influenced by overall facial attractiveness. Experimental study. University of Bern, Switzerland. Seventy-two fused images (36 of boys, 36 of girls) were constructed. Each image comprised (1) the nasolabial region of a treated child with complete unilateral CLP (UCLP) and (2) the external facial features, i.e., the face with masked nasolabial region, of a noncleft child. Photographs of the nasolabial region of six boys and six girls with UCLP representing a wide range of esthetic outcomes, i.e., from very good to very poor appearance, were randomly chosen from a sample of 60 consecutively treated patients in whom nasolabial esthetics had been rated in a previous study. Photographs of external facial features of six boys and six girls without UCLP with various esthetics were randomly selected from patients' files. Eight lay raters evaluated the fused images using a 100-mm visual analogue scale. Method reliability was assessed by reevaluation of fused images after >1 month. A regression model was used to analyze which elements of facial esthetics influenced the perception of nasolabial appearance. Method reliability was good. A regression analysis demonstrated that only the appearance of the nasolabial area affected the esthetic scores of fused images (coefficient = -11.44; P < .001; R(2) = 0.464). The appearance of the external facial features did not influence perceptions of fused images. Cropping facial images for assessment of nasolabial appearance in CLP seems unnecessary. Instead, esthetic evaluation can be performed on images of full faces.

PROTECTIVELY COVERED ARTICLE AND METHOD OF MANUFACTURE

DOEpatents

Plott, R.F.

1958-10-28

A method of casting a protective jacket about a ura nium fuel element that will bond completely to the uranium without the use of stringers or supports that would ordinarily produce gaps in the cast metal coating and bond is presented. Preformed endcaps of alumlnum alloyed with 13% silicon are placed on the ends of the uranium fuel element. These caps will support the fuel element when placed in a mold. The mold is kept at a ing alloy but below that of uranium so the cast metal jacket will fuse with the endcaps forming a complete covering and bond to the fuel element, which would otherwise oxidize at the gaps or discontinuities lefi in the coating by previous casting methods.

Iterative Bayesian Estimation of Travel Times on Urban Arterials: Fusing Loop Detector and Probe Vehicle Data.

PubMed

Liu, Kai; Cui, Meng-Ying; Cao, Peng; Wang, Jiang-Bo

2016-01-01

On urban arterials, travel time estimation is challenging especially from various data sources. Typically, fusing loop detector data and probe vehicle data to estimate travel time is a troublesome issue while considering the data issue of uncertain, imprecise and even conflicting. In this paper, we propose an improved data fusing methodology for link travel time estimation. Link travel times are simultaneously pre-estimated using loop detector data and probe vehicle data, based on which Bayesian fusion is then applied to fuse the estimated travel times. Next, Iterative Bayesian estimation is proposed to improve Bayesian fusion by incorporating two strategies: 1) substitution strategy which replaces the lower accurate travel time estimation from one sensor with the current fused travel time; and 2) specially-designed conditions for convergence which restrict the estimated travel time in a reasonable range. The estimation results show that, the proposed method outperforms probe vehicle data based method, loop detector based method and single Bayesian fusion, and the mean absolute percentage error is reduced to 4.8%. Additionally, iterative Bayesian estimation performs better for lighter traffic flows when the variability of travel time is practically higher than other periods.

Iterative Bayesian Estimation of Travel Times on Urban Arterials: Fusing Loop Detector and Probe Vehicle Data

PubMed Central

Cui, Meng-Ying; Cao, Peng; Wang, Jiang-Bo

2016-01-01

On urban arterials, travel time estimation is challenging especially from various data sources. Typically, fusing loop detector data and probe vehicle data to estimate travel time is a troublesome issue while considering the data issue of uncertain, imprecise and even conflicting. In this paper, we propose an improved data fusing methodology for link travel time estimation. Link travel times are simultaneously pre-estimated using loop detector data and probe vehicle data, based on which Bayesian fusion is then applied to fuse the estimated travel times. Next, Iterative Bayesian estimation is proposed to improve Bayesian fusion by incorporating two strategies: 1) substitution strategy which replaces the lower accurate travel time estimation from one sensor with the current fused travel time; and 2) specially-designed conditions for convergence which restrict the estimated travel time in a reasonable range. The estimation results show that, the proposed method outperforms probe vehicle data based method, loop detector based method and single Bayesian fusion, and the mean absolute percentage error is reduced to 4.8%. Additionally, iterative Bayesian estimation performs better for lighter traffic flows when the variability of travel time is practically higher than other periods. PMID:27362654

Thermally induced distortion of a high-average-power laser system by an optical transport system

NASA Astrophysics Data System (ADS)

Chow, Robert; Ault, Linda E.; Taylor, John R.; Jedlovec, Don

1999-11-01

The atomic vapor laser isotope separation process uses high- average power lasers that have the commercial potential to enrich uranium for the electric power utilities. The transport of the laser beam through the laser system to the separation chambers requires high performance optical components, most of which have either fused silica or Zerodur as the substrate material. One of the requirements of the optical components is to preserve the wavefront quality of the laser beam that propagate over long distances. Full aperture tests with the high power process lasers and finite element analysis (FEA) have been performed on the transport optics. The wavefront distortions of the various sections of the transport path were measured with diagnostic Hartmann sensor packages. The FEA results were derived from an in-house thermal-structural- optical code which is linked to the commercially available CodeV program. In comparing the measured and predicted results, the bulk absorptance of fused silica was estimated to about 50 ppm/cm in the visible wavelength regime. Wavefront distortions will be reported on optics made from fused silica and Zerodur substrate materials.

The Abundances of the Fe Group Elements in Early B Stars in the Magellanic Clouds and Bridge

NASA Astrophysics Data System (ADS)

Peters, Geraldine J.; Adelman, Saul J.

2016-01-01

The abundances of three Fe Group elements (V, Cr, and Fe) in 9 early main-sequence band B stars in the LMC, 7 in the SMC , and two in the Magellanic Bridge have been determined from archival FUSE observations and the Hubeny/Lanz NLTE programs TLUSTY/SYNSPEC. Lines from the Fe group elements, except for a few weak multiplets of Fe III, are not observable in the optical spectral region. The best set of lines in the FUSE spectral region are Fe III (UV1), V III 1150 Å, and Cr III 1137 Å. The abundances of these elements in early B stars are a marker for recent SNe Ia activity, as a single exploding white dwarf can deliver 0.5 solar masses of Ni-56 that decays into Fe to the ISM. The Fe group abundances in an older population of stars primarily reflect SNe II activity, in which a single explosion delivers only 0.07 solar masses of Ni-56 to the ISM (the rest remains trapped in the neutron star). The abundances of the Fe group elements in early B stars not only track SNe Ia activity but are also important for computing evolutionary tracks for massive stars. In general, the Fe abundance relative to the sun's value is comparable to the mean abundances for the lighter elements in the Clouds/Bridge but the values of [V,Cr/Fe]sun are smaller. This presentation will discuss the spatial distribution of the Fe Group elements in the Magellanic Clouds, and compare it with our galaxy in which the abundance of Fe declines with radial distance from the center. Support from NASA grants NAG5-13212, NNX10AD66G, STScI HST-GO-13346.22, and USC's Women in Science and Engineering (WiSE) program is greatly appreciated.

Heat accumulation regime of femtosecond laser writing in fused silica and Nd:phosphate glass

NASA Astrophysics Data System (ADS)

Bukharin, M. A.; Khudyakov, D. V.; Vartapetov, S. K.

2015-04-01

We investigated refractive index induced by direct femtosecond laser writing inside fused silica and Nd:phosphate glass in heat accumulation regime. Spatial profile and magnitude of induced refractive index were investigated at various pulse repetition rates and translation velocities. It was shown that the magnitude of induced refractive index significantly rises with decreasing in time interval between successive laser pulses below the time for thermal diffusion. Going from nonthermal regime to heat accumulation regime, we achieved induced refractive index growth from 4 × 10-3 up to 6.5 × 10-3 in fused silica and from -6 × 10-3 to -9 × 10-3 in Nd:phosphate glass. Aspect ratio of treated area decreased from 2.1 down to less than 1.5 without correcting optical elements. It was shown that in heat accumulation regime, the treated area was surrounded by region of alternatively changed refractive index with significant magnitude up to -2 × 10-3. Wide regions of decreased refractive index enable fabrication of depressed cladding waveguides. We demonstrated low-loss (0.3 dB/cm) tubular waveguide inside fused silica. For orthogonal polarizations of guiding light, we achieved a small difference between losses as 0.1 dB/cm using highly symmetric written tracks forming the cladding. The desired structure was simulated with the beam propagation method, and the results were in good agreement with experiment data.

FPGA-Based Fused Smart-Sensor for Tool-Wear Area Quantitative Estimation in CNC Machine Inserts

PubMed Central

Trejo-Hernandez, Miguel; Osornio-Rios, Roque Alfredo; de Jesus Romero-Troncoso, Rene; Rodriguez-Donate, Carlos; Dominguez-Gonzalez, Aurelio; Herrera-Ruiz, Gilberto

2010-01-01

Manufacturing processes are of great relevance nowadays, when there is a constant claim for better productivity with high quality at low cost. The contribution of this work is the development of a fused smart-sensor, based on FPGA to improve the online quantitative estimation of flank-wear area in CNC machine inserts from the information provided by two primary sensors: the monitoring current output of a servoamplifier, and a 3-axis accelerometer. Results from experimentation show that the fusion of both parameters makes it possible to obtain three times better accuracy when compared with the accuracy obtained from current and vibration signals, individually used. PMID:22319304

46 CFR 111.30-17 - Protection of instrument circuits.

Code of Federal Regulations, 2011 CFR

2011-10-01

... circuit of a current transformer must not be fused, and the circuit from a current transformer to a device that is not in the switchboard must have a high voltage protector to short the transformer during an...

46 CFR 111.30-17 - Protection of instrument circuits.

Code of Federal Regulations, 2014 CFR

2014-10-01

... circuit of a current transformer must not be fused, and the circuit from a current transformer to a device that is not in the switchboard must have a high voltage protector to short the transformer during an...

46 CFR 111.30-17 - Protection of instrument circuits.

Code of Federal Regulations, 2012 CFR

2012-10-01

... circuit of a current transformer must not be fused, and the circuit from a current transformer to a device that is not in the switchboard must have a high voltage protector to short the transformer during an...

46 CFR 111.30-17 - Protection of instrument circuits.

Code of Federal Regulations, 2010 CFR

2010-10-01

... circuit of a current transformer must not be fused, and the circuit from a current transformer to a device that is not in the switchboard must have a high voltage protector to short the transformer during an...

46 CFR 111.30-17 - Protection of instrument circuits.

Code of Federal Regulations, 2013 CFR

2013-10-01

... circuit of a current transformer must not be fused, and the circuit from a current transformer to a device that is not in the switchboard must have a high voltage protector to short the transformer during an...

Nondestructive test determines overload destruction characteristics of current limiter fuses

NASA Technical Reports Server (NTRS)

Swartz, G. A.

1968-01-01

Nondestructive test predicts the time required for current limiters to blow /open the circuit/ when subjected to a given overload. The test method is based on an empirical relationship between the voltage rise across a current limiter for a fixed time interval and the time to blow.

Visualizing Caribbean Performance (Jamaican Dancehall and Trinidadian Carnival) as Praxis: An Autohistoria of Kiki's Journey

ERIC Educational Resources Information Center

Carey, A'Keitha

2016-01-01

I discuss my journey in the construction, pedagogy, and philosophy of the dance technique CaribFunk™. CaribFunk fuses Afro-Caribbean (traditional and social dance), classical ballet, modern, and fitness elements. It also encourages exploration of self while investigating identity, citizenship, and culture through a kinesthetic expression of the…

Polishing techniques for MEGARA pupil elements optics

NASA Astrophysics Data System (ADS)

Izazaga, R.; Carrasco, E.; Aguirre, D.; Salas, A.; Gil de Paz, A.; Gallego, J.; Iglesias, J.; Arroyo, J. M.; Hernández, M.; López, N.; López, V.; Quechol, J. T.; Salazar, M. F.; Carballo, C.; Cruz, E.; Arriaga, J.; De la Luz, J. A.; Huepa, A.; Jaimes, G. L.; Reyes, J.

2016-07-01

MEGARA (Multi-Espectrógrafo en GTC de Alta Resolución para Astronomía) is the new integral-field and multi-object optical spectrograph for the 10.4m Gran Telescopio Canarias.. It will offer RFWHM 6,000, 12,000 and 18,700 for the low- , mid- and high-resolution, respectively in the wavelength range 3650-9700Å. .The dispersive elements are volume phase holographic (VPH) gratings, sandwiched between two flat Fused Silica windows of high optical precision in large apertures. The design, based in VPHs in combination with Ohara PBM2Y prisms allows to keep the collimator and camera angle fixed. Seventy three optical elements are being built in Mexico at INAOE and CIO. For the low resolution modes, the VPHs windows specifications in irregularity is 1 fringe in 210mm x 170mm and 0.5 fringe in 190mm x 160mm. for a window thickness of 25 mm. For the medium and high resolution modes the irregularity specification is 2 fringes in 220mm x 180mm and 1 fringe in 205mm x 160mm, for a window thickness of 20mm. In this work we present a description of the polishing techniques developed at INAOE optical workshop to fabricate the 36 Fused Silica windows and 24 PBM2Y prisms that allows us to achieve such demanding specifications. We include the processes of mounting, cutting, blocking, polishing and testing.

Polyethylene glycol treated allografts not tissue matched nor immunosuppressed rapidly repair sciatic nerve gaps, maintain neuromuscular functions, and restore voluntary behaviors in female rats.

PubMed

Mikesh, Michelle; Ghergherehchi, Cameron L; Rahesh, Sina; Jagannath, Karthik; Ali, Amir; Sengelaub, Dale R; Trevino, Richard C; Jackson, David M; Tucker, Haley O; Bittner, George D

2018-07-01

Many publications report that ablations of segments of peripheral nerves produce the following unfortunate results: (1) Immediate loss of sensory signaling and motor control; (2) rapid Wallerian degeneration of severed distal axons within days; (3) muscle atrophy within weeks; (4) poor behavioral (functional) recovery after many months, if ever, by slowly-regenerating (∼1mm/d) axon outgrowths from surviving proximal nerve stumps; and (5) Nerve allografts to repair gap injuries are rejected, often even if tissue matched and immunosuppressed. In contrast, using a female rat sciatic nerve model system, we report that neurorrhaphy of allografts plus a well-specified-sequence of solutions (one containing polyethylene glycol: PEG) successfully addresses each of these problems by: (a) Reestablishing axonal continuity/signaling within minutes by nonspecific ally PEG-fusing (connecting) severed motor and sensory axons across each anastomosis; (b) preventing Wallerian degeneration by maintaining many distal segments of inappropriately-reconnected, PEG-fused axons that continuously activate nerve-muscle junctions; (c) maintaining innervation of muscle fibers that undergo much less atrophy than otherwise-denervated muscle fibers; (d) inducing remarkable behavioral recovery to near-unoperated levels within days to weeks, almost certainly by CNS and PNS plasticities well-beyond what most neuroscientists currently imagine; and (e) preventing rejection of PEG-fused donor nerve allografts with no tissue matching or immunosuppression. Similar behavioral results are produced by PEG-fused autografts. All results for Negative Control allografts agree with current neuroscience data 1-5 given above. Hence, PEG-fusion of allografts for repair of ablated peripheral nerve segments expand on previous observations in single-cut injuries, provoke reconsideration of some current neuroscience dogma, and further extend the potential of PEG-fusion in clinical practice. © 2018 Wiley Periodicals, Inc.

Viscoelastic analysis of a dental metal-ceramic system

NASA Astrophysics Data System (ADS)

Özüpek, Şebnem; Ünlü, Utku Cemal

2012-11-01

Porcelain-fused-to-metal (PFM) restorations used in prosthetic dentistry contain thermal stresses which develop during the cooling phase after firing. These thermal stresses coupled with the stresses produced by mechanical loads may be the dominant reasons for failures in clinical situations. For an accurate calculation of these stresses, viscoelastic behavior of ceramics at high temperatures should not be ignored. In this study, the finite element technique is used to evaluate the effect of viscoelasticity on stress distributions of a three-point flexure test specimen, which is the current international standard, ISO 9693, to characterize the interfacial bond strength of metal-ceramic restorative systems. Results indicate that the probability of interfacial debonding due to normal tensile stress is higher than that due to shear stress. This conclusion suggests modification of ISO 9693 bond strength definition from one in terms of the shear stress only to that accounting for both normal and shear stresses.

The effect of high-pressure devitrification and densification on ballistic-penetration resistance of fused silica

NASA Astrophysics Data System (ADS)

Avuthu, Vasudeva Reddy

Despite the clear benefits offered by more advanced transparent materials, (e.g. transparent ceramics offer a very attractive combination of high stiffness and high hardness levels, highly-ductile transparent polymers provide superior fragment-containing capabilities, etc.), ballistic ceramic-glass like fused-silica remains an important constituent material in a majority of transparent impact-resistant structures (e.g. windshields and windows of military vehicles, portholes in ships, ground vehicles and spacecraft) used today. Among the main reasons for the wide-scale use of glass, the following three are most frequently cited: (i) glass-structure fabrication technologies enable the production of curved, large surface-area, transparent structures with thickness approaching several inches; (ii) relatively low material and manufacturing costs; and (iii) compositional modifications, chemical strengthening, and controlled crystallization have been demonstrated to be capable of significantly improving the ballistic properties of glass. In the present work, the potential of high-pressure devitrification and densification of fused-silica as a ballistic-resistance-enhancement mechanism is investigated computationally. In the first part of the present work, all-atom molecular-level computations are carried out to infer the dynamic response and material microstructure/topology changes of fused silica subjected to ballistic impact by a nanometer-sized hard projectile. The analysis was focused on the investigation of specific aspects of the dynamic response and of the microstructural changes such as the deformation of highly sheared and densified regions, and the conversion of amorphous fused silica to SiO2 crystalline allotropic modifications (in particular, alpha-quartz and stishovite). The microstructural changes in question were determined by carrying out a post-processing atom-coordination procedure. This procedure suggested the formation of high-density stishovite (and perhaps alpha-quartz) within fused silica during ballistic impact. To rationalize the findings obtained, the all-atom molecular-level computational analysis is complemented by a series of quantum-mechanics density functional theory (DFT) computations. The latter computations enable determination of the relative potential energies of the fused silica, alpha-quartz and stishovite under ambient pressure (i.e. under their natural densities) as well as under imposed (as high as 50 GPa) pressures (i.e. under higher densities) and shear strains. In addition, the transition states associated with various fused-silica devitrification processes were identified. In the second part of the present work, the molecular-level computational results obtained in the first portion of the work are used to enrich a continuum-type constitutive model (that is, the so-called Johnson-Holmquist-2, JH2, model) for fused silica. Since the aforementioned devitrification and permanent-densification processes modify the response of fused silica to the pressure as well as to the deviatoric part of the stress, changes had to be made in both the JH2 equation of state and the strength model. To assess the potential improvements with respect to the ballistic-penetration resistance of this material brought about by the fused-silica devitrification and permanent-densification processes, a series of transient non-linear dynamics finite element analyses of the transverse impact of a fused-silica test plate with a solid right-circular cylindrical steel projectile was conducted. The results obtained revealed that, provided the projectile incident velocity and, hence, the attendant pressure, is sufficiently high, fused silica can undergo impact-induced energy-consuming devitrification, which improves its ballistic-penetration resistance.

Human ossicular-joint flexibility transforms the peak amplitude and width of impulsive acoustic stimulia)

PubMed Central

Gottlieb, Peter K.; Vaisbuch, Yona

2018-01-01

The role of the ossicular joints in the mammalian middle ear is still debated. This work tests the hypothesis that the two synovial joints filter potentially damaging impulsive stimuli by transforming both the peak amplitude and width of these impulses before they reach the cochlea. The three-dimensional (3D) velocity along the ossicular chain in unaltered cadaveric human temporal bones (N = 9), stimulated with acoustic impulses, is measured in the time domain using a Polytec (Waldbronn, Germany) CLV-3D laser Doppler vibrometer. The measurements are repeated after fusing one or both of the ossicular joints with dental cement. Sound transmission is characterized by measuring the amplitude, width, and delay of the impulsive velocity profile as it travels from the eardrum to the cochlea. On average, fusing both ossicular joints causes the stapes velocity amplitude and width to change by a factor of 1.77 (p = 0.0057) and 0.78 (p = 0.011), respectively. Fusing just the incudomalleolar joint has a larger effect on amplitude (a factor of 2.37), while fusing just the incudostapedial joint decreases the stapes velocity on average. The 3D motion of the ossicles is altered by fusing the joints. Finally, the ability of current computational models to predict this behavior is also evaluated.

Investigation of the Static and Dynamic Characteristics for a Wafer-Fused C-band VCSEL in the Mode of the Optical-Electric Converter

NASA Astrophysics Data System (ADS)

Belkin, M. E.

2018-01-01

The results of an experimental study for a long wavelength vertical cavity surface-emitting laser of a wafer-fused construction as an effective resonant cavity enhanced photodetector of analog optical signals are described. The device is of interest for a number of promising microwave photonics applications and for creation of a low-cost photoreceiver in a high-speed fiber optics telecommunication system with dense wavelength division multiplexing. The schematic of the testbed, the original technique allowing to calculate the passband of the built-in optical cavity, and the results of measuring dark current, current responsivity, amplitude- and phase-frequency characteristics during the process of photo-detection are demonstrated.

Advanced UVOIR Mirror Technology Development (AMTD) for Very Large Space Telescopes

NASA Technical Reports Server (NTRS)

Postman, Marc; Soummer, Remi; Sivramakrishnan, Annand; Macintosh, Bruce; Guyon, Olivier; Krist, John; Stahl, H. Philip; Smith, W. Scott; Mosier, Gary; Kirk, Charles;

Optical absorption in fused silica at elevated temperatures during 1.5-MeV electron irradiation

NASA Technical Reports Server (NTRS)

Smith, A. B.

1972-01-01

An experimental determination of the optical transmission of Corning 7940 UV and Suprasil 1 and 2 fused silica has been made during 1.5-MeV electron bombardment. The fused silica reached temperatures ranging from 150 to 1000 C. The Lewis Research Center dynamitron provided electron current densities which corresponded to a dose rate of 2.6 to 20 Mrad/sec. The irradiation induced absorption was measured at 215.0, 270.0, and 450.0 nm (2150, 2700, 4500 A). The length of each irradiation was sufficient so that an equilibrium between radiation induced coloration and high temperature annealing was reached. The experimental results indicate a significant optical absorption, with values of the induced absorption coefficient at 215.0 nm (2150 A) of 14.5 to 2.2/cm, at 270.0 nm (2700 A) of 9.7 to 3.0/cm and at 450.0 nm (4500 A) of 3.7 to 0.5/cm. This would make the use of fused silica as the separating wall material in the nuclear light bulb propulsion concept questionable.

Thermally induced distortion of high average power laser system by an optical transport system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ault, L; Chow, R; Taylor, Jedlovec, D

1999-03-31

The atomic vapor laser isotope separation process uses high-average power lasers that have the commercial potential to enrich uranium for the electric power utilities. The transport of the laser beam through the laser system to the separation chambers requires high performance optical components, most of which have either fused silica or Zerodur as the substrate material. One of the requirements of the optical components is to preserve the wavefront quality of the laser beam that propagate over long distances. Full aperture tests with the high power process lasers and finite element analysis (FEA) have been performed on the transport optics.more » The wavefront distortions of the various sections of the transport path were measured with diagnostic Hartmann sensor packages. The FEA results were derived from an in-house thermal-structural-optical code which is linked to the commercially available CodeV program. In comparing the measured and predicted results, the bulk absorptance of fused silica was estimated to about 50 ppm/cm in the visible wavelength regime. Wavefront distortions are reported on optics made from fused silica and Zerodur substrate materials.« less

Extended depth of field integral imaging using multi-focus fusion

NASA Astrophysics Data System (ADS)

Piao, Yongri; Zhang, Miao; Wang, Xiaohui; Li, Peihua

2018-03-01

In this paper, we propose a new method for depth of field extension in integral imaging by realizing the image fusion method on the multi-focus elemental images. In the proposed method, a camera is translated on a 2D grid to take multi-focus elemental images by sweeping the focus plane across the scene. Simply applying an image fusion method on the elemental images holding rich parallax information does not work effectively because registration accuracy of images is the prerequisite for image fusion. To solve this problem an elemental image generalization method is proposed. The aim of this generalization process is to geometrically align the objects in all elemental images so that the correct regions of multi-focus elemental images can be exacted. The all-in focus elemental images are then generated by fusing the generalized elemental images using the block based fusion method. The experimental results demonstrate that the depth of field of synthetic aperture integral imaging system has been extended by realizing the generation method combined with the image fusion on multi-focus elemental images in synthetic aperture integral imaging system.

Multi-dimension feature fusion for action recognition

NASA Astrophysics Data System (ADS)

Dong, Pei; Li, Jie; Dong, Junyu; Qi, Lin

2018-04-01

Typical human actions last several seconds and exhibit characteristic spatio-temporal structure. The challenge for action recognition is to capture and fuse the multi-dimension information in video data. In order to take into account these characteristics simultaneously, we present a novel method that fuses multiple dimensional features, such as chromatic images, depth and optical flow fields. We built our model based on the multi-stream deep convolutional networks with the help of temporal segment networks and extract discriminative spatial and temporal features by fusing ConvNets towers multi-dimension, in which different feature weights are assigned in order to take full advantage of this multi-dimension information. Our architecture is trained and evaluated on the currently largest and most challenging benchmark NTU RGB-D dataset. The experiments demonstrate that the performance of our method outperforms the state-of-the-art methods.

Simultaneous qubit-loss-free fusion of three multiple W states

NASA Astrophysics Data System (ADS)

Wang, Meiyu; Hao, Quanzhi; Yan, Fengli; Gao, Ting

2018-05-01

Qubit-loss-free fusion for two W states introduced by Li K et al (2016 Phys. Rev. A 94 062315) clearly increases the final size of the obtained W state and greatly reduces the number of fusion steps to achieve a W state of a target size. Motivated by this idea, we propose a qubit-loss-free fusion scheme for fusing three polarization entangled W states simultaneously. The elements of a two-outcome positive-operator valued measurement and the appropriate joint unitary operation for realizing a positive-operator valued measurement measurement are given. As an example, with the assistance of weak cross-Kerr nonlinearities, an optical setup for fusing three W states is proposed. We analyze the success probability of the scheme and the resource cost of the present scheme, as compared to previous work.

46 CFR 129.220 - Basic safety.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., fuses, and lampholders, must be suitable for the voltage and current used. (c) Receptacle outlets of the type providing a grounded pole or a specific direct-current polarity must be of a configuration that does not permit improper connection. (d) Electrical equipment and circuits must be clearly marked and...

46 CFR 129.220 - Basic safety.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., fuses, and lampholders, must be suitable for the voltage and current used. (c) Receptacle outlets of the type providing a grounded pole or a specific direct-current polarity must be of a configuration that does not permit improper connection. (d) Electrical equipment and circuits must be clearly marked and...

Things That Go Boom!: Noise and Toxic Exposures Associated with Weapon Systems

DTIC Science & Technology

2010-06-17

Munitions Pyrotechnics Tracers Spot ing Charges Oxidizers Delay Elements Propellatl s Fuses De· onators Pr~n1ers Constituent of Concern BariL ...r11 chromate Potassium perchlorate lead oxide BariL m chromate P a tass ~L m perch I o r,ate l e ad chromate An1n1onil tll perch lara e P a

Usefulness of a Dual Macro- and Micro-Energy-Dispersive X-Ray Fluorescence Spectrometer to Develop Quantitative Methodologies for Historic Mortar and Related Materials Characterization.

PubMed

García-Florentino, Cristina; Maguregui, Maite; Romera-Fernández, Miriam; Queralt, Ignasi; Margui, Eva; Madariaga, Juan Manuel

2018-05-01

Wavelength dispersive X-ray fluorescence (WD-XRF) spectrometry has been widely used for elemental quantification of mortars and cements. In this kind of instrument, samples are usually prepared as pellets or fused beads and the whole volume of sample is measured at once. In this work, the usefulness of a dual energy dispersive X-ray fluorescence spectrometer (ED-XRF), working at two lateral resolutions (1 mm and 25 μm) for macro and microanalysis respectively, to develop quantitative methods for the elemental characterization of mortars and concretes is demonstrated. A crucial step before developing any quantitative method with this kind of spectrometers is to verify the homogeneity of the standards at these two lateral resolutions. This new ED-XRF quantitative method also demonstrated the importance of matrix effects in the accuracy of the results being necessary to use Certified Reference Materials as standards. The results obtained with the ED-XRF quantitative method were compared with the ones obtained with two WD-XRF quantitative methods employing two different sample preparation strategies (pellets and fused beads). The selected ED-XRF and both WD-XRF quantitative methods were applied to the analysis of real mortars. The accuracy of the ED-XRF results turn out to be similar to the one achieved by WD-XRF, except for the lightest elements (Na and Mg). The results described in this work proved that μ-ED-XRF spectrometers can be used not only for acquiring high resolution elemental map distributions, but also to perform accurate quantitative studies avoiding the use of more sophisticated WD-XRF systems or the acid extraction/alkaline fusion required as destructive pretreatment in Inductively coupled plasma mass spectrometry based procedures.

46 CFR 120.220 - General safety provisions.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., including switches, fuses, lampholders, etc., must be suitable for the voltage and current utilized. (c) Receptacle outlets of the type providing a grounded pole or a specific direct current polarity must be of a configuration that will not permit improper connection. (d) All electrical equipment and circuits must be...

46 CFR 120.220 - General safety provisions.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., including switches, fuses, lampholders, etc., must be suitable for the voltage and current utilized. (c) Receptacle outlets of the type providing a grounded pole or a specific direct current polarity must be of a configuration that will not permit improper connection. (d) All electrical equipment and circuits must be...

30 CFR 77.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., which is ignited by electric current, or the spark of a fuse. Used for detonating explosives. (h) Blasting circuit means electric circuits used to fire electric detonators or to ignite an igniter cord by... where miners are normally required to work or travel; (b) American Table of Distances means the current...

30 CFR 77.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., which is ignited by electric current, or the spark of a fuse. Used for detonating explosives. (h) Blasting circuit means electric circuits used to fire electric detonators or to ignite an igniter cord by... where miners are normally required to work or travel; (b) American Table of Distances means the current...

30 CFR 77.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., which is ignited by electric current, or the spark of a fuse. Used for detonating explosives. (h) Blasting circuit means electric circuits used to fire electric detonators or to ignite an igniter cord by... where miners are normally required to work or travel; (b) American Table of Distances means the current...

The FUSE Survey of Algol-Type Interacting Binary Systems

NASA Astrophysics Data System (ADS)

Peters, Geraldine J.; Andersson, B.; Ake, T. B.; Sankrit, R.

2006-12-01

A survey of Algol binaries at random phases is currently being carried through with the FUSE spacecraft as part of the FUSE survey and supplemental program. A similar program was undertaken in FUSE Cycle 3. Both programs have produced multiple observations of 12 Algol systems with periods ranging from 1.2 37 d and include direct-impact and disk systems. We report on the status of the program. The absence of O VI absorption in the systems observed to date allows us to place an upper limit on the column density and temperature of the High Temperature Accretion Region, HTAR ( 100,000 K) confirmed in some Algols from earlier IUE data. The HTAR plasma component appears to be distinct from an O VI-emitting polar plasma discovered in FUSE totality observations of RY Per, V356 Sgr, and TT Hya. New observations of the direct-impact system U Cep have provided more information on the geometry and mass flow (including a splash plasma) in the vicinity of a hot spot at phase 0.90 that was discovered earlier. The extent of disk asymmetries in the long period ( 33 d) systems SX Cas and RX Cas is discussed. Models for direct-impact and the disk systems will be presented. The authors appreciate support from NASA grants NAG5-12253, NNG04GL17G, and NAS5-32985.

Eta Car: The Good, the Bad and the Ugly of Nebular and Stellar Confusion

NASA Technical Reports Server (NTRS)

Gull, T.R.; Sonneborn, G.; Jensen, A.G.; Nielsen, K.E.; Vieira Kover, G.; Hillier, D.J.

2008-01-01

Observations in the far-UV provide a unique opportunity to investigate the very massive star Eta Car and its hot binary companion, Eta Car B. Eta Car was observed with FUSE over a large portion of the 5.54 year spectroscopic period before and after the 2003.5 minimum. The observed spectrum is defined by strong stellar wind signatures, primarily from Eta Car A, complicated by the strong absorptions of the ejecta surrounding Eta Car plus interstellar absorption. The Homunculus and Little Homunculus are massive bipolar ejecta historically associable with LBV outbursts in the 1840s and the 1890s and are linked to absorptions at -513 and -146 km/s, respectively. The FUSE spectra are confused by the extended nebulosity and thermal drifting of the FUSE co-pointed instruments. Interpretation is further complicated by two B-stars sufficiently close to h Car to be included most of the time in the large FUSE aperture. Followup observations partially succeeded in obtaining spectra of at least one of these B-stars through the smaller apertures, allowing potential separation of the B-star contributions and h Car. A complete analysis of all available spectra is currently underway. Our ultimate goals are to directly detect the hot secondary star if possible with FUSE and to identify the absorption contributions to the overall spectrum especially of the stellar members and the massive ejecta.

30 CFR 28.40 - Construction and performance requirements; general.

Code of Federal Regulations, 2010 CFR

2010-07-01

...-CIRCUIT PROTECTION FOR TRAILING CABLES IN COAL MINES Construction, Performance, and Testing Requirements... for use with direct current in providing short-circuit protection for trailing cables, when such fuses...

A quantitative assay for mitochondrial fusion using Renilla luciferase complementation

PubMed Central

Huang, Huiyan; Choi, Seok-Yong; Frohman, Michael A.

2010-01-01

Mitochondria continuously undergo fusion and fission, the relative rates of which define their morphology. Large mitochondria produce energy more efficiently, whereas small mitochondria translocate better to subcellular sites where local production of ATP is acutely required. Mitochondrial fusion is currently assayed by fusing together cells expressing GFP or RFP in their mitochondria and then scoring the frequency of cells with yellow mitochondria (representing fused green and red mitochondria). However, this assay is labor-intensive and only semi-quantitative. We describe here a reporter system consisting of split fragments of Renilla luciferase and YFP fused to mitochondrial matrix-targeting sequences and to leucine zippers to trigger dimerization. The assay enables fusion to be quantitated both visually for individual cells and on a population level using chemiluminescence, laying the foundation for high throughput small molecule and RNAi screens for modulators of mitochondrial fusion. We use the assay to examine cytoskeletal roles in fusion progression. PMID:20488258

Optically imprinted reconfigurable photonic elements in a VO{sub 2} nanocomposite

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jostmeier, Thorben; Betz, Markus; Zimmer, Johannes

We investigate the optical and thermal hysteresis of single-domain vanadium dioxide nanocrystals fabricated by ion beam synthesis in a fused silica matrix. The nanocrystals exhibit a giant hysteresis, which permits to optically generate a long-time stable supercooled metallic phase persistent down to practically room temperature. Spatial patterns of supercooled and insulating nanocrystals feature a large dielectric contrast, in particular, for telecom wavelengths. We utilize this contrast to optically imprint reconfigurable photonic elements comprising diffraction gratings as well as on- and off-axis zone plates. The structures allow for highly repetitive (>10{sup 4}) cycling through the phase transition without structural damage.

Single-point diamond crushing of Zerodur with in-situ polishing and metrology on a diamond turning machine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bryan, J.B.; Carter, D.L.

1985-04-01

Large, complicated, aspherical optical elements of glass are presently used in many astronomical devices, both on land and in space. Grazing-incident mirrors are envisioned for use in such missions as the proposed Advanced X-Ray Astrophysical Facility (AXAF), the Far Ultraviolet Spectroscopic Explorer (FUSE), and others. These elements are very expensive to fabricate because a great deal of time and labor are required to shape a glass blank. The fabrication of these mirrors can best be achieved by applying precision machining techniques and precision machines for figuring and finishing low-expansion glasses such as Zerodur.

30 CFR 28.10 - Application procedures.

Code of Federal Regulations, 2010 CFR

2010-07-01

... TRAILING CABLES IN COAL MINES Application for Approval § 28.10 Application procedures. (a) Each applicant seeking approval of a fuse for use with direct current in providing short-circuit protection for trailing...

A tool for measuring the bending length in thin wires

NASA Astrophysics Data System (ADS)

Lorenzini, M.; Cagnoli, G.; Cesarini, E.; Losurdo, G.; Martelli, F.; Piergiovanni, F.; Vetrano, F.; Viceré, A.

2013-03-01

Great effort is currently being put into the development and construction of the second generation, advanced gravitational wave detectors, Advanced Virgo and Advanced LIGO. The development of new low thermal noise suspensions of mirrors, based on the experience gained in the previous experiments, is part of this task. Quasi-monolithic suspensions with fused silica wires avoid the problem of rubbing friction introduced by steel cradle arrangements by directly welding the wires to silica blocks bonded to the mirror. Moreover, the mechanical loss level introduced by silica (ϕfs ˜ 10-7 in thin fused silica wires) is by far less than the one associated with steel. The low frequency dynamical behaviour of the suspension can be computed and optimized, provided that the wire bending shape under pendulum motion is known. Due to the production process, fused silica wires are thicker near the two ends (necks), so that analytical bending computations are very complicated. We developed a tool to directly measure the low frequency bending parameters of fused silica wires, and we tested it on the wires produced for the Virgo+ monolithic suspensions. The working principle and a set of test measurements are presented and explained.

A tool for measuring the bending length in thin wires.

PubMed

Lorenzini, M; Cagnoli, G; Cesarini, E; Losurdo, G; Martelli, F; Piergiovanni, F; Vetrano, F; Viceré, A

2013-03-01

Great effort is currently being put into the development and construction of the second generation, advanced gravitational wave detectors, Advanced Virgo and Advanced LIGO. The development of new low thermal noise suspensions of mirrors, based on the experience gained in the previous experiments, is part of this task. Quasi-monolithic suspensions with fused silica wires avoid the problem of rubbing friction introduced by steel cradle arrangements by directly welding the wires to silica blocks bonded to the mirror. Moreover, the mechanical loss level introduced by silica (φfs ∼ 10(-7) in thin fused silica wires) is by far less than the one associated with steel. The low frequency dynamical behaviour of the suspension can be computed and optimized, provided that the wire bending shape under pendulum motion is known. Due to the production process, fused silica wires are thicker near the two ends (necks), so that analytical bending computations are very complicated. We developed a tool to directly measure the low frequency bending parameters of fused silica wires, and we tested it on the wires produced for the Virgo+ monolithic suspensions. The working principle and a set of test measurements are presented and explained.

Interface modification based ultrashort laser microwelding between SiC and fused silica.

PubMed

Zhang, Guodong; Bai, Jing; Zhao, Wei; Zhou, Kaiming; Cheng, Guanghua

2017-02-06

It is a big challenge to weld two materials with large differences in coefficients of thermal expansion and melting points. Here we report that the welding between fused silica (softening point, 1720°C) and SiC wafer (melting point, 3100°C) is achieved with a near infrared femtosecond laser at 800 nm. Elements are observed to have a spatial distribution gradient within the cross section of welding line, revealing that mixing and inter-diffusion of substances have occurred during laser irradiation. This is attributed to the femtosecond laser induced local phase transition and volume expansion. Through optimizing the welding parameters, pulse energy and interval of the welding lines, a shear joining strength as high as 15.1 MPa is achieved. In addition, the influence mechanism of the laser ablation on welding quality of the sample without pre-optical contact is carefully studied by measuring the laser induced interface modification.

Contested identities: gendered politics, gendered religion in Pakistan.

PubMed

Shaheed, Farida

2010-01-01

In Pakistan, the self-serving use of Islam by more secular elements alongside politico-religious ones facilitated the latter's increasing influence and the conflation and intricate interweaving of Islam and Pakistani nationhood. A paradigm shift under Zia's martial law revamped society as much as state laws, producing both religiously defined militias and aligned civil society groups. Examining the impact on women of fusing religion and politics, this paper argues that women become symbolic markers of appropriated territory in the pursuit of state power, and that the impact of such fusing, different for differently situated women, needs to be gauged in societal terms as well as in terms of state dynamics. Questioning the positing of civil society as a self-evident progressive desideratum, the paper concludes that gender equality projects seeking reconfigurations of power cannot be effective without vigorously competing in the creation of knowledge, culture and identity.

Synthesis of Some Novel Fused Pyrimido[4″,5″:5',6']-[1,2,4]triazino[3',4':3,4] [1,2,4]triazino[5,6-b]indoles with Expected Anticancer Activity.

PubMed

Ali, Rania S; Saad, Hosam A

2018-03-19

Our current goal is the synthesis of polyheterocyclic compounds starting from 3-amino-[1,2,4]triazino[5,6- b ]indole 1 and studying their anticancer activity to determine whether increasing of the size of the molecules increases the anticancer activity or not. 1-Amino[1,2,4]triazino[3',4':3,4]-[1,2,4]triazino[5,6- b ]indole-2-carbonitrile ( 4 ) was prepared by the diazotization of 3-amino[1,2,4]-triazino[5,6- b ]indole 1 followed by coupling with malononitrile in basic medium then cyclization under reflux to get 4 . Also, new fused pyrimido[4″,5″:5',6'][1,2,4]triazino-[3',4':3,4][1,2,4]triazino[5,6- b ]indole derivative 6 was prepared and used to obtain polycyclic heterocyclic systems. Confirmation of the synthesized compounds' structures was carried out using elemental analyses and spectral data (IR, ¹H-NMR and 13 C-NMR and mass spectra). The anticancer activity of some of the synthesized compounds was tested against HepG2, HCT-116 and MCF-7 cell lines. The anticancer screening results showed that some derivatives display good activity which was more potent than that of the reference drug used. Molecular docking was used to predict the binding between some of the synthesized compounds and the prostate cancer 2q7k hormone and breast ‎cancer 3hb5 receptors.

Translational regulation of sigma 32 synthesis: requirement for an internal control element.

PubMed Central

Kamath-Loeb, A S; Gross, C A

1991-01-01

We have investigated the sequence requirements for the translational regulation of sigma 32 by examining the behavior of a new rpoH-lacZ protein fusion containing a short N-terminal fragment of sigma 32 fused to beta-galactosidase. Although the fusion retains rpoH translational initiation signals, it lacks translational regulation, implicating coding sequences within rpoH in this regulatory process. Images PMID:2050641

Fusing Open Source Intelligence and Handheld Situational Awareness - Benghazi Case Study

DTIC Science & Technology

2014-10-01

of the Battlespace (IPB) • Link OSINT to mobile SA 5 DM-0001694 Background • Between September 11 and 17, 2012, diplomatic missions in the...explore what might have been possible by integrating social media information ( OSINT ) with traditional intelligence combined with improved mobile...command and control element at the CIA compound that would have been monitoring OSINT and other sources of intelligence before the attack and

Peculiar Abundances Observed in the Hot Subdwarf OB Star LB 3241

NASA Astrophysics Data System (ADS)

Chayer, Pierre; Dupuis, J.; Dixon, W. V.; Giguere, E.

2010-01-01

We present a spectral synthesis analysis of the hot subdwarf OB star LB 3241. The analysis is based on spectra obtained by the Far Ultraviolet Spectroscopic Explorer (FUSE). With an effective temperature of 41,000 K and a gravity of log g = 5.7, the position of LB 3241 in a Teff-log g diagram suggests that it has evolved from the extreme horizontal branch. Such stars evolve into white dwarfs without ascending the asymptotic giant branch after the helium core exhaustion. Arsenic (Z = 33), selenium (34), and tellurium (52) are observed in the atmosphere of LB 3241, and are a first for a hot subdwarf star. LB 3241 shows peculiar chemical abundances that exhibit trends observed in cooler sdB stars. The content of its atmosphere in light elements is about a factor ten lower than that of the Sun, except for nitrogen which has a solar abundance. The Fe abundance is consistent with a solar abundance, but abundances of elements beyond the iron peak (As, Se, Te, Pb) show enrichments over the solar values by factors ranging from 10 to 300. These observations suggest that competing mechanisms must counterbalance the effects of the downward diffusion. The FUSE observations also suggest that LB 3241 is a radial velocity variable.

Vertebral architecture in the earliest stem tetrapods.

PubMed

Pierce, Stephanie E; Ahlberg, Per E; Hutchinson, John R; Molnar, Julia L; Sanchez, Sophie; Tafforeau, Paul; Clack, Jennifer A

2013-02-14

The construction of the vertebral column has been used as a key anatomical character in defining and diagnosing early tetrapod groups. Rhachitomous vertebrae--in which there is a dorsally placed neural arch and spine, an anteroventrally placed intercentrum and paired, posterodorsally placed pleurocentra--have long been considered the ancestral morphology for tetrapods. Nonetheless, very little is known about vertebral anatomy in the earliest stem tetrapods, because most specimens remain trapped in surrounding matrix, obscuring important anatomical features. Here we describe the three-dimensional vertebral architecture of the Late Devonian stem tetrapod Ichthyostega using propagation phase-contrast X-ray synchrotron microtomography. Our scans reveal a diverse array of new morphological, and associated developmental and functional, characteristics, including a possible posterior-to-anterior vertebral ossification sequence and the first evolutionary appearance of ossified sternal elements. One of the most intriguing features relates to the positional relationships between the vertebral elements, with the pleurocentra being unexpectedly sutured or fused to the intercentra that directly succeed them, indicating a 'reverse' rhachitomous design. Comparison of Ichthyostega with two other stem tetrapods, Acanthostega and Pederpes, shows that reverse rhachitomous vertebrae may be the ancestral condition for limbed vertebrates. This study fundamentally revises our current understanding of vertebral column evolution in the earliest tetrapods and raises questions about the presumed vertebral architecture of tetrapodomorph fish and later, more crownward, tetrapods.

Adaptive beam shaping by controlled thermal lensing in optical elements

NASA Astrophysics Data System (ADS)

Arain, Muzammil A.; Quetschke, Volker; Gleason, Joseph; Williams, Luke F.; Rakhmanov, Malik; Lee, Jinho; Cruz, Rachel J.; Mueller, Guido; Tanner, D. B.; Reitze, David. H.

2007-04-01

We describe an adaptive optical system for use as a tunable focusing element. The system provides adaptive beam shaping via controlled thermal lensing in the optical elements. The system is agile, remotely controllable, touch free, and vacuum compatible; it offers a wide dynamic range, aberration-free focal length tuning, and can provide both positive and negative lensing effects. Focusing is obtained through dynamic heating of an optical element by an external pump beam. The system is especially suitable for use in interferometric gravitational wave interferometers employing high laser power, allowing for in situ control of the laser modal properties and compensation for thermal lensing of the primary laser. Using CO2 laser heating of fused-silica substrates, we demonstrate a focal length variable from infinity to 4.0 m, with a slope of 0.082 diopter/W of absorbed heat. For on-axis operation, no higher-order modes are introduced by the adaptive optical element. Theoretical modeling of the induced optical path change and predicted thermal lens agrees well with measurement.

Adaptive beam shaping by controlled thermal lensing in optical elements.

PubMed

Arain, Muzammil A; Quetschke, Volker; Gleason, Joseph; Williams, Luke F; Rakhmanov, Malik; Lee, Jinho; Cruz, Rachel J; Mueller, Guido; Tanner, D B; Reitze, David H

2007-04-20

We describe an adaptive optical system for use as a tunable focusing element. The system provides adaptive beam shaping via controlled thermal lensing in the optical elements. The system is agile, remotely controllable, touch free, and vacuum compatible; it offers a wide dynamic range, aberration-free focal length tuning, and can provide both positive and negative lensing effects. Focusing is obtained through dynamic heating of an optical element by an external pump beam. The system is especially suitable for use in interferometric gravitational wave interferometers employing high laser power, allowing for in situ control of the laser modal properties and compensation for thermal lensing of the primary laser. Using CO(2) laser heating of fused-silica substrates, we demonstrate a focal length variable from infinity to 4.0 m, with a slope of 0.082 diopter/W of absorbed heat. For on-axis operation, no higher-order modes are introduced by the adaptive optical element. Theoretical modeling of the induced optical path change and predicted thermal lens agrees well with measurement.

Modeling Thermal Noise from Crystaline Coatings for Gravitational-Wave Detectors

NASA Astrophysics Data System (ADS)

Demos, Nicholas; Lovelace, Geoffrey; LSC Collaboration

2016-03-01

The sensitivity of current and future ground-based gravitational-wave detectors are, in part, limited in sensitivity by Brownian and thermoelastic noise in each detector's mirror substrate and coating. Crystalline mirror coatings could potentially reduce thermal noise, but thermal noise is challenging to model analytically in the case of crystalline materials. Thermal noise can be modeled using the fluctuation-dissipation theorem, which relates thermal noise to an auxiliary elastic problem. In this poster, I will present results from a new code that numerically models thermal noise by numerically solving the auxiliary elastic problem for various types of crystalline mirror coatings. The code uses a finite element method with adaptive mesh refinement to model the auxiliary elastic problem which is then related to thermal noise. I will present preliminary results for a crystal coating on a fused silica substrate of varying sizes and elastic properties. This and future work will help develop the next generation of ground-based gravitational-wave detectors.

Low-loss VIS/IR-XUV beam splitter for high-power applications.

PubMed

Pupeza, Ioachim; Fill, Ernst E; Krausz, Ferenc

2011-06-20

We present a low-loss VIS/IR-XUV beam splitter, suitable for high-power operation. The spatial separation of the VIS/IR and XUV components of a beam is achieved by the wedged top layer of a dielectric multilayer structure, onto which the beam is impinging under Brewster's angle (for VIS/IR). With a fused silica wedge with an angle of 0.5° we achieve a separation angle of 2.2° and an IR reflectivity of 0.9995. Typical XUV reflectivities amount to 0.1-0.2. The novel element is mechanically robust, exhibiting two major advantages over free-standing Brewster plates: (i) a significant improvement of heat conduction and (ii) easier handling, in particular for high-optical-quality fabrication. The beam splitter could be used as an output coupler for intracavity-generated XUV radiation, promising a boost of the power regime of current MHz-HHG experiments. It is also suited for single-pass experiments and as a beam combiner for pump-probe experiments.

Influence of Solute Content and Solidification Parameters on Grain Refinement of Aluminum Weld Metal

NASA Astrophysics Data System (ADS)

Schempp, Philipp; Cross, Carl Edward; Pittner, Andreas; Rethmeier, Michael

2013-07-01

Grain refinement provides an important possibility to enhance the mechanical properties ( e.g., strength and ductility) and the weldability (susceptibility to solidification cracking) of aluminum weld metal. In the current study, a filler metal consisting of aluminum base metal and different amounts of commercial grain refiner Al Ti5B1 was produced. The filler metal was then deposited in the base metal and fused in a GTA welding process. Additions of titanium and boron reduced the weld metal mean grain size considerably and resulted in a transition from columnar to equiaxed grain shape ( CET). In commercial pure aluminum (Alloy 1050A), the grain-refining efficiency was higher than that in the Al alloys 6082 and 5083. Different welding and solidification parameters influenced the grain size response only slightly. Furthermore, the observed grain-size reduction was analyzed by means of the undercooling parameter P and the growth restriction parameter Q, which revealed the influence of solute elements and nucleant particles on grain size.

Operations of the Far Ultraviolet Spectroscopic Explorer : A `Dynamic' Flux Calibration.

NASA Astrophysics Data System (ADS)

Ehrenreich, D.; Dupuis, J.; Dixon, W. V.; Sahnow, D. J.; Kruk, J. W.

2003-05-01

The FUSE flux calibration is based on model-atmosphere predictions of the spectra of well studied white-dwarf stars. Calibration operations, however, are a highly `dynamic' process consisting of repeatedly measuring these standard stars, deriving corrections, and integrating the results into CALFUSE, the FUSE science pipeline. With suitable scheduling, those calibration observation campaigns let us characterize short term and long term variations of the sensitivity. One particular issue addressed by these observations is monitoring possible degradation of the FUSE optical coatings by atomic oxygen present in the upper atmosphere. We have attempted to minimize this by avoiding pointing close to the instantaneous velocity vector of the spacecraft (the ram vector). Prior to Cycle 3, the minimum permitted angle between the line of sight and the ram vector was 20 degrees. This was reduced to 15 degrees during Cycle 3 to increase our sky coverage, and will be further reduced to 10 degrees for Cycle 4. This relaxation of ram constraints has been preceded by a tailored calibration program in which white dwarf measurements are obtained before and after observations performed for a limited time below the current ram vector constraint. This relaxation of the ram vector constraint will considerably expand the ability of FUSE to observe sources at low declination. This work is based on data obtained for the Guaranteed Time Team by the NASA-CNES-CSA FUSE mission operated by the Johns Hopkins University. Financial support to U.S. participants has been provided by NASA contract NAS5-32985.

Laser-Raman/Rayleigh Flow Diagnostic Techniques Applied to Subsonic Flow

DTIC Science & Technology

1980-10-01

the problem of interpreting test results. Advances in electronics and laser technology have made it possible to perform measurements (which formerly...will increase with increasing gas density. It was the latter quality that made the prospect for successful subsonic flow-field measurements very...elements in the optical system were made of fused silica. An aperture was located at the entrance slit of the spectrometer and adjusted so that a 0.25-in

Development of Theoretical and Computational Methods for Single-Source Bathymetric Data

DTIC Science & Technology

2016-09-15

Methods for Single-Source N00014-16-1-2035 Bathymetric Data Sb. GRANT NUMBER 11893686 Sc. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Sd. PROJECT NUMBER...A method is outlined for fusing the information inherent in such source documents, at different scales, into a single picture for the marine...algorithm reliability, which reflects the degree of inconsistency of the source documents, is also provided. A conceptual outline of the method , and a

Discovering disease-disease associations by fusing systems-level molecular data

PubMed Central

Žitnik, Marinka; Janjić, Vuk; Larminie, Chris; Zupan, Blaž; Pržulj, Nataša

2013-01-01

The advent of genome-scale genetic and genomic studies allows new insight into disease classification. Recently, a shift was made from linking diseases simply based on their shared genes towards systems-level integration of molecular data. Here, we aim to find relationships between diseases based on evidence from fusing all available molecular interaction and ontology data. We propose a multi-level hierarchy of disease classes that significantly overlaps with existing disease classification. In it, we find 14 disease-disease associations currently not present in Disease Ontology and provide evidence for their relationships through comorbidity data and literature curation. Interestingly, even though the number of known human genetic interactions is currently very small, we find they are the most important predictor of a link between diseases. Finally, we show that omission of any one of the included data sources reduces prediction quality, further highlighting the importance in the paradigm shift towards systems-level data fusion. PMID:24232732

Discovering disease-disease associations by fusing systems-level molecular data.

PubMed

Žitnik, Marinka; Janjić, Vuk; Larminie, Chris; Zupan, Blaž; Pržulj, Nataša

2013-11-15

The advent of genome-scale genetic and genomic studies allows new insight into disease classification. Recently, a shift was made from linking diseases simply based on their shared genes towards systems-level integration of molecular data. Here, we aim to find relationships between diseases based on evidence from fusing all available molecular interaction and ontology data. We propose a multi-level hierarchy of disease classes that significantly overlaps with existing disease classification. In it, we find 14 disease-disease associations currently not present in Disease Ontology and provide evidence for their relationships through comorbidity data and literature curation. Interestingly, even though the number of known human genetic interactions is currently very small, we find they are the most important predictor of a link between diseases. Finally, we show that omission of any one of the included data sources reduces prediction quality, further highlighting the importance in the paradigm shift towards systems-level data fusion.

Luna 16 - Some Li, K, Rb, Sr, Ba, rare-earth, Zr, and Hf concentrations.

NASA Technical Reports Server (NTRS)

Philpotts, J. A.; Schnetzler, C. C.; Schuhmann, S.; Thomas , H. H.; Bottino, M. L.

1972-01-01

Concentrations of Li, K, Rb, Sr, Na, rare-earths, Zr and Hf have been determined for some Luna 16 core materials by mass-spectrometric isotope-dilution. Two regolith fines samples from different depths in the core, and four rock-chips, including both igneous rocks and breccias, have similar trace-element concentrations. The Luna 16 materials have general lunar trace-element characteristics but differ from other returned lunar samples in a manner that suggests the presence of excess feldspar. Unless the Luna 16 igneous rocks are fused soils, they appear to represent either partial plagioclase cumulates or the least differentiated igneous material yet returned from the moon. The similarity in trace-element concentrations of the igneous rocks and the fines would then suggest largely local derivation of the Luna 16 regolith.

AN ONLINE CATALOG OF CATACLYSMIC VARIABLE SPECTRA FROM THE FAR-ULTRAVIOLET SPECTROSCOPIC EXPLORER

DOE Office of Scientific and Technical Information (OSTI.GOV)

Godon, Patrick; Sion, Edward M.; Levay, Karen

2012-12-15

We present an online catalog containing spectra and supporting information for cataclysmic variables that have been observed with the Far-Ultraviolet Spectroscopic Explorer (FUSE). For each object in the catalog we list some of the basic system parameters such as (R.A., decl.), period, inclination, and white dwarf mass, as well as information on the available FUSE spectra: data ID, observation date and time, and exposure time. In addition, we provide parameters needed for the analysis of the FUSE spectra such as the reddening E(B - V), distance, and state (high, low, intermediate) of the system at the time it was observed.more » For some of these spectra we have carried out model fits to the continuum with synthetic stellar and/or disk spectra using the codes TLUSTY and SYNSPEC. We provide the parameters obtained from these model fits; this includes the white dwarf temperature, gravity, projected rotational velocity, and elemental abundances of C, Si, S, and N, together with the disk mass accretion rate, the resulting inclination, and model-derived distance (when unknown). For each object one or more figures are provided (as gif files) with line identification and model fit(s) when available. The FUSE spectra and the synthetic spectra are directly available for download as ASCII tables. References are provided for each object, as well as for the model fits. In this article we present 36 objects, and additional ones will be added to the online catalog in the future. In addition to cataclysmic variables, we also include a few related objects, such as a wind-accreting white dwarf, a pre-cataclysmic variable, and some symbiotics.« less

Identification of choriogenin cis-regulatory elements and production of estrogen-inducible, liver-specific transgenic Medaka.

PubMed

Ueno, Tetsuro; Yasumasu, Shigeki; Hayashi, Shinji; Iuchi, Ichiro

2004-07-01

Choriogenins (chg-H, chg-L) are precursor proteins of egg envelope of medaka and synthesized in the spawning female liver in response to estrogen. We linked a gene construct chg-L1.5 kb/GFP (a 1.5 kb 5'-upstream region of the chg-L gene fused with a green fluorescence protein (GFP) gene) to another construct emgb/RFP (a cis-regulatory region of embryonic globin gene fused with an RFP gene), injected the double fusion gene construct into 1- or 2-cell-stage embryos, and selected embryos expressing the RFP in erythroid cells. From the embryos, we established two lines of chg-L1.5 kb/GFP-emgb/RFP-transgenic medaka. The 3-month-old spawning females and estradiol-17beta (E2)-exposed males displayed the liver-specific GFP expression. The E2-dependent GFP expression was detected in the differentiating liver of the stage 37-38 embryos. In addition, RT-PCR and whole-mount in situ hybridization showed that the E2-dependent chg expression was found in the liver of the stage 34 embryos of wild medaka, suggesting that such E2-dependency is achieved shortly after differentiation of the liver. Analysis using serial deletion mutants fused with GFP showed that the region -426 to -284 of the chg-L gene or the region -364 to -265 of the chg-H gene had the ability to promote the E2-dependent liver-specific GFP expression of its downstream gene. Further analyses suggested that an estrogen response element (ERE) at -309, an ERE half-site at -330 and a binding site for C/EBP at -363 of the chg-L gene played important roles in its downstream chg-L gene expression. In addition, this transgenic medaka may be useful as one of the test animals for detecting environmental estrogenic steroids.

Mitigating intrinsic defects and laser damage using pulsetrain-burst (>100 MHz) ultrafast laser processing

NASA Astrophysics Data System (ADS)

McKinney, Luke; Frank, Felix; Graper, David; Dean, Jesse; Forrester, Paul; Rioblanc, Maxence; Nantel, Marc; Marjoribanks, Robin

2005-09-01

Ultrafast-laser micromachining has promise as an approach to trimming and 'healing' small laser-produced damage sites in laser-system optics--a common experience in state-of-the-art high-power laser systems. More-conventional approaches currently include mechanical micromachining, chemical modification, and treatment using cw and long-pulse lasers. Laser-optics materials of interest include fused silica, multilayer dielectric stacks for anti-reflection coatings or high-reflectivity mirrors, and inorganic crystals such as KD*P, used for Pockels cells and frequency-doubling. We report on novel efforts using ultrafast-laser pulsetrain-burst processing (microsecond bursts at 133 MHz) to mitigate damage in fused silica, dielectric coatings, and KD*P crystals. We have established the characteristics of pulsetrain-burst micromachining in fused silica, multilayer mirrors, and KD*P, and determined the etch rates and morphology under different conditions of fluence-delivery. From all of these, we have begun to identify new means to optimize the laser-repair of optics defects and damage.

A quantitative assay for mitochondrial fusion using Renilla luciferase complementation.

PubMed

Huang, Huiyan; Choi, Seok-Yong; Frohman, Michael A

2010-08-01

Mitochondria continuously undergo fusion and fission, the relative rates of which define their morphology. Large mitochondria produce energy more efficiently, whereas small mitochondria translocate better to subcellular sites where local production of ATP is acutely required. Mitochondrial fusion is currently assayed by fusing together cells expressing GFP or RFP in their mitochondria and then scoring the frequency of cells with yellow mitochondria (representing fused green and red mitochondria). However, this assay is labor-intensive and only semi-quantitative. We describe here a reporter system consisting of split fragments of Renilla luciferase and YFP fused to mitochondrial matrix-targeting sequences and to leucine zippers to trigger dimerization. The assay enables fusion to be quantitated both visually for individual cells and on a population level using chemiluminescence, laying the foundation for high throughput small molecule and RNAi screens for modulators of mitochondrial fusion. We use the assay to examine cytoskeletal roles in fusion progression. (c) 2010 Mitochondria Research Society. Published by Elsevier B.V. All rights reserved.

Electrochromic conductive polymer fuses for hybrid organic/inorganic semiconductor memories

NASA Astrophysics Data System (ADS)

Möller, Sven; Forrest, Stephen R.; Perlov, Craig; Jackson, Warren; Taussig, Carl

2003-12-01

We demonstrate a nonvolatile, write-once-read-many-times (WORM) memory device employing a hybrid organic/inorganic semiconductor architecture consisting of thin film p-i-n silicon diode on a stainless steel substrate integrated in series with a conductive polymer fuse. The nonlinearity of the silicon diodes enables a passive matrix memory architecture, while the conductive polyethylenedioxythiophene:polystyrene sulfonic acid polymer serves as a reliable switch with fuse-like behavior for data storage. The polymer can be switched at ˜2 μs, resulting in a permanent decrease of conductivity of the memory pixel by up to a factor of 103. The switching mechanism is primarily due to a current and thermally dependent redox reaction in the polymer, limited by the double injection of both holes and electrons. The switched device performance does not degrade after many thousand read cycles in ambient at room temperature. Our results suggest that low cost, organic/inorganic WORM memories are feasible for light weight, high density, robust, and fast archival storage applications.

A FUSE Search for Argon on Titan

NASA Astrophysics Data System (ADS)

Gladstone, G. R.; Link, R.; Stern, S. A.; Festou, M.; Waite, J. H.

2002-09-01

The origin of Titan's thick nitrogen and methane atmosphere is a compelling enigma. One key and still missing observable concerns the abundances of noble gases in general, and argon in particular. Detection of sufficient argon could indicate that the N2 and CO now found in the atmosphere came in with ice during Titan's accretion. Alternatively, if there is very little argon, then we have to turn to models starting with frozen ammonia, methane and water ice, indicating a more important role for the Saturn sub-nebula, and requiring subsequent modification by photochemistry. Current estimates on the fraction of argon in Titan's atmosphere are crude, and based only on indirect evidence, and range up to 25%. On Sept. 21, 2000, using the Far Ultraviolet Spectroscopic Explorer (FUSE) satellite, we performed an observation of Titan to search for argon and to make a survey of Titan's dayglow in the 90--115 nm FUSE bandpass. No emissions were found in the 18 ks exposure, although only 7.4 ks were obtained when FUSE was in Earth's shadow where terrestrial airglow contamination is minimal. While no Ar, N, or N2 emissions were detected, 2-σ upper limits of 4 R (for Ar 104.8 nm) and 20 R (for N 113.4 nm) are found using the best of the FUSE data. There is a bump on the terrestrial geocorona H Lyβ emission at 102.5 nm which may be due to Titan and a Titan Torus. The signal in the bump is about 400 R. Model estimates suggest that the Lyβ brightness of Titan should be about 20 R and the Titan Torus in the 30--700 R range. For an assumed argon abundance of 5% the 104.8 nm emission is predicted to be 7 R, so the argon estimate is constraining already. The nitrogen estimate is very close to the model expectation of 15 R. An accurate determination of the abundance of argon on Titan would be useful in preparing for the arrival of the Cassini orbiter and Huygens probe at the Saturn system, so further FUSE observations of Titan are planned. We gratefully acknowledge support from NASA through FUSE grant NAG5-9972.

PV Systems Reliability Final Technical Report: Ground Fault Detection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lavrova, Olga; Flicker, Jack David; Johnson, Jay

We have examined ground faults in PhotoVoltaic (PV) arrays and the efficacy of fuse, current detection (RCD), current sense monitoring/relays (CSM), isolation/insulation (Riso) monitoring, and Ground Fault Detection and Isolation (GFID) using simulations based on a Simulation Program with Integrated Circuit Emphasis SPICE ground fault circuit model, experimental ground faults installed on real arrays, and theoretical equations.

Vectors for Treatment of Metastatic Breast Cancer

DTIC Science & Technology

2006-08-01

Breast Cancer 5b. GRANT NUMBER DAMD17-03-1-0554 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Albert B. Deisseroth, M.D., Ph.D. 5d. PROJECT NUMBER...14. ABSTRACT: The objective is to design, build and study vectors which would be able to break tolerance to breast cancer associated TAA and to be...used to suppress the recurrence of metastatic breast cancer following surgical resection. The hypothesis is that by fusing the CD40 ligand stripped of

Laser-gyro materials studies

NASA Astrophysics Data System (ADS)

Covino, J.; Bennett, J. M.

1986-03-01

Material properties of low-expansion glass and glass-ceramic materials have been measured. The materials that have been characterized are ultralow-expansion (ULE) type 7971 quartz, a new glass-ceramic material RLA 559,122 from Corning Glass Works, fused quartz from General Electric, Zerodur from Schott Glaswerke, and Cervit C-101 from Owens-Illinois. Characterization has included measurements of X-ray powder diffraction patterns, some elemental analyses, helium permeability, thermal expansion, particle-size distributions, optical properties, and optical finish studies.

Overtone Vibrations of OH Groups in Fused Silica Optical Fibers.

DTIC Science & Technology

1981-09-01

MER IPEFRIGORGANIZATION- NAME AND ADDRESS - 10. PROGRAM ELEMENT, PROJECT, TS Chemitry eparmentAREA & WORK UNIT NUMBERS Howard-University Washington D...edameutal and overtone contours were decomposed into Gaussian components using a D. Post 310 analog computer . ?~ .5- 3. F..*’m,,ntal Re,.ults A. Infrared...spectrum. AoD - k AoH (here k-3.981) computed S from a linear combination of deuterated, AOD, and undeuterated, AoH, absorbance spectra, was required, Fig

Separation of Californium from other Actinides

DOEpatents

Mailen, J C; Ferris, L M

1973-09-25

A method is provided for separating californium from a fused fluoride composition containing californium and at least one element selected from the group consisting of plutonium, americium, curium, uranium, thorium, and protactinium which comprises contacting said fluoride composition with a liquid bismuth phase containing sufficient lithium or thorium to effect transfer of said actinides to the bismuth phase and then contacting the liquid bismuth phase with molten LiCl to effect selective transfer of californium to the chloride phase.

Interstellar Deuterium, Nitrogen and Oxygen Towards HZ43A: Results from the Far Ultraviolet Spectroscopic Explorer (FUSE) Mission

NASA Technical Reports Server (NTRS)

Kruk, J. W.; Howk, J. C.; Andre, M.; Moos, H. W.; Oegerle, William R.; Oliveira, C.; Sembach, K. R.; Chayer, P.; Linsky, J. L.; Wood, B. E.

2002-01-01

We present an analysis of interstellar absorption along the line of sight to the nearby white dwarf star HZ43A. The distance to this star is 68+/-13 pc, and the line of sight extends toward the north Galactic pole. Column densities of O(I), N(I), and N(II) were derived from spectra obtained by the Far Ultraviolet Spectroscopic Explorer (FUSE), the column density of D(I) was derived from a combination of our FUSE spectra and an archival HST GARDENS spectrum, and the column density of H(I) was derived from a combination of the GARDENS spectrum and values derived from EUVE data obtained from the literature. We find the following abundance ratios (with 2 sigma uncertainties): D(I)/H(I)=(1.66+/-0.28)x10(exp -5), O(I)/H(I)=(3.63+/-0.84)x10(exp -4), and N(I)/H(I)=(3.80+/-0.74)x10(exp -5). The N(II) column density was slightly greater than that of N(I), indicating that ionization corrections are important when deriving nitrogen abundances. Other interstellar species detected along the line of sight were C(II), C(III), O(VI), Si(II), Ar(I), Mg(II) and Fe(II); an upper limit was determined for N(III). No elements other than H(I) were detected in the stellar photosphere.

Verification of an IGBT Fusing Switch for Over-current Protection of the SNS HVCM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Benwell, Andrew; Kemp, Mark; Burkhart, Craig

2010-06-11

An IGBT based over-current protection system has been developed to detect faults and limit the damage caused by faults in high voltage converter modulators. During normal operation, an IGBT enables energy to be transferred from storage capacitors to a H-bridge. When a fault occurs, the over-current protection system detects the fault, limits the fault current and opens the IGBT to isolate the remaining stored energy from the fault. This paper presents an experimental verification of the over-current protection system under applicable conditions.

An Atlas of Far-ultraviolet Spectra of the Zeta Aurigae Binary 31 Cygni with Line Identifications

NASA Astrophysics Data System (ADS)

Hagen Bauer, Wendy; Bennett, Philip D.

2014-04-01

The ζ Aurigae system 31 Cygni (K4 Ib + B4 V) was observed by the FUSE satellite during total eclipse and at three phases during chromospheric eclipse. We present the coadded, calibrated spectra and atlases with line identifications. During total eclipse, emission from high ionization states (e.g., Fe III and Cr III) shows asymmetric profiles redshifted from the systemic velocity, while emission from lower ionization states (e.g., Fe II and O I) appears more symmetric and is centered closer to the systemic velocity. Absorption from neutral and singly ionized elements is detected during chromospheric eclipse. Late in chromospheric eclipse, absorption from the K star wind is detected at a terminal velocity of ~80 km s-1. These atlases will be useful for interpreting the far-UV spectra of other ζ Aur systems, as the observed FUSE spectra of 32 Cyg, KQ Pup, and VV Cep during chromospheric eclipse resemble that of 31 Cyg.

Finite element thermal analysis of multispectral coatings for the ABL

NASA Astrophysics Data System (ADS)

Shah, Rashmi S.; Bettis, Jerry R.; Stewart, Alan F.; Bonsall, Lynn; Copland, James; Hughes, William; Echeverry, Juan C.

1999-04-01

The thermal response of a coated optical surface is an important consideration in the design of any high average power system. Finite element temperature distribution were calculated for both coating witness samples and calorimetry wafers and were compared to actual measured data under tightly controlled conditions. Coatings for ABL were deposited on various substrates including fused silica, ULE, Zerodur, and silicon. The witness samples were irradiate data high power levels at 1.315micrometers to evaluate laser damage thresholds and study absorption levels. Excellent agreement was obtained between temperature predictions and measured thermal response curves. When measured absorption values were not available, the code was used to predict coating absorption based on the measured temperature rise on the back surface. Using the finite element model, the damaging temperature rise can be predicted for a coating with known absorption based on run time, flux, and substrate material.

Determination of arsenic, antimony, bismuth, cadmium, copper, lead, molybdenum, silver and zinc in geological materials by atomic-absorption spectrometry

USGS Publications Warehouse

Viets, J.G.; O'Leary, R. M.; Clark, Robert J.

1984-01-01

Arsenic, antimony, bismuth, cadmium, copper, lead, molybdenum, silver and zinc are very useful elements in geochemical exploration. In the proposed method, geological samples are fused with potassium pyrosulphate and the fusate is dissolved in a solution of hydrochloric acid, ascorbic acid and potassium iodide. When this solution is shaken with a 10% V/V Aliquat 336 - isobutyl methyl ketone organic phase, the nine elements of interest are selectively partitioned in the organic phase. All nine elements can then be determined in the organic phase using flame atomic-absorption spectrometry. The method is rapid and allows the determination of Ag and Cd at levels down to 0.1 p.p.m., Cu, Mo, and Zn down to 0.5 p.p.m., Pb, Bi and Sb down to 1 p.p.m. and As down to 5 p.p.m. in geological materials.

A 20 bp cis-acting element is both necessary and sufficient to mediate elicitor response of a maize PRms gene.

PubMed

Raventós, D; Jensen, A B; Rask, M B; Casacuberta, J M; Mundy, J; San Segundo, B

1995-01-01

Transient gene expression assays in barley aleurone protoplasts were used to identify a cis-regulatory element involved in the elicitor-responsive expression of the maize PRms gene. Analysis of transcriptional fusions between PRms 5' upstream sequences and a chloramphenicol acetyltransferase reporter gene, as well as chimeric promoters containing PRms promoter fragments or repeated oligonucleotides fused to a minimal promoter, delineated a 20 bp sequence which functioned as an elicitor-response element (ERE). This sequence contains a motif (-246 AATTGACC) similar to sequences found in promoters of other pathogen-responsive genes. The analysis also indicated that an enhancing sequence(s) between -397 and -296 is required for full PRms activation by elicitors. The protein kinase inhibitor staurosporine was found to completely block the transcriptional activation induced by elicitors. These data indicate that protein phosphorylation is involved in the signal transduction pathway leading to PRms expression.

Metal-free current collectors based on graphene materials for supecapacitors produced by 3D printing

NASA Astrophysics Data System (ADS)

Baskakov, S. A.; Baskakova, Yu. V.; Lyskov, N. V.; Dremova, N. N.; Shul'ga, Yu. M.

2017-10-01

Supercapacitor (SC) current collectors with electrodes made of graphite oxide reduced during microwave exfoliation are produced from a commercial filament with a graphene component via layer-by-layer fusing with a 3D printer. The separator is made of a graphene oxide film. The current collectors are investigated by means of IR spectroscopy. Electrochemical tests are performed for the assembled SC that include tests of its cyclic stability up to 1000 cycles.

Probability of growth of small damage sites on the exit surface of fused silica optics.

PubMed

Negres, Raluca A; Abdulla, Ghaleb M; Cross, David A; Liao, Zhi M; Carr, Christopher W

2012-06-04

Growth of laser damage on fused silica optical components depends on several key parameters including laser fluence, wavelength, pulse duration, and site size. Here we investigate the growth behavior of small damage sites on the exit surface of SiO₂ optics under exposure to tightly controlled laser pulses. Results demonstrate that the onset of damage growth is not governed by a threshold, but is probabilistic in nature and depends both on the current size of a damage site and the laser fluence to which it is exposed. We also develop models for use in growth prediction. In addition, we show that laser exposure history also influences the behavior of individual sites.

(F)UV Spectroscopy of K648: Abundance Determination of Trace Elements

NASA Astrophysics Data System (ADS)

Mohamad-Yob, S. J.; Ziegler, M.; Rauch, T.; Werner, K.

2010-11-01

We present preliminary results of an ongoing spectral analysis of K 648, the central star of the planetary nebula Ps 1, based on high resolution FUV spectra. K 648, in M 15 is one of only four known PNe in globular clusters. The formation of this post-AGB object in a globular cluster is still unclear. Our aim is to determine Teff, log g, and the abundances of trace elements, in order to improve our understanding of post-AGB evolution of extremely metal-poor stars, especially PN formation in globular clusters. We analyzed FUSE, HST/STIS, and HST/FOS observations. A grid of stellar model atmospheres was calculated using the Tübingen NLTE Model Atmosphere Package (TMAP).

Semi-flexible gas-insulated transmission line using sandwiched discs for intermittent flexing joints

DOEpatents

Kommineni, P.R.

1983-02-15

A gas-insulated transmission line includes an outer sheath, an inner conductor, an insulating gas electrically insulating the inner conductor from the outer sheath, and insulating supports insulatably supporting the inner conductor within the outer sheath. The inner conductor is provided with flexibility by the use of main conductor sections which are joined together through a conductor hub section and flexible flexing elements. Stress shields are provided to control the electric field at the locations of the conductor hub sections where the insulating supports are contacting the inner conductor. The flexing elements are formed by sandwiching together, by fusing, a pair of thin hollow discs which are fixedly secured to both the main conductor sections and the conductor hub section. 4 figs.

Nickel-Cadmium Battery Charger.

DTIC Science & Technology

1981-02-23

cells (3) 6 thermistors (4) 2 thermostats (5) 4 fuses (6) 3 hetter blankets 5a L . . .. _ . . . . . . .. . . . .. . . •. . . ,- NAI2C-92-i 45 g. There is...current measurement. q. Connector and wiring continuity testing. r. Provisions for soldering and welding connector and cell termina- tions. IV

The 'F-complex' and MMN tap different aspects of deviance.

PubMed

Laufer, Ilan; Pratt, Hillel

2005-02-01

To compare the 'F(fusion)-complex' with the Mismatch negativity (MMN), both components associated with automatic detection of changes in the acoustic stimulus flow. Ten right-handed adult native Hebrew speakers discriminated vowel-consonant-vowel (V-C-V) sequences /ada/ (deviant) and /aga/ (standard) in an active auditory 'Oddball' task, and the brain potentials associated with performance of the task were recorded from 21 electrodes. Stimuli were generated by fusing the acoustic elements of the V-C-V sequences as follows: base was always presented in front of the subject, and formant transitions were presented to the front, left or right in a virtual reality room. An illusion of a lateralized echo (duplex sensation) accompanied base fusion with the lateralized formant locations. Source current density estimates were derived for the net response to the fusion of the speech elements (F-complex) and for the MMN, using low-resolution electromagnetic tomography (LORETA). Statistical non-parametric mapping was used to estimate the current density differences between the brain sources of the F-complex and the MMN. Occipito-parietal regions and prefrontal regions were associated with the F-complex in all formant locations, whereas the vicinity of the supratemporal plane was bilaterally associated with the MMN, but only in case of front-fusion (no duplex effect). MMN is sensitive to the novelty of the auditory object in relation to other stimuli in a sequence, whereas the F-complex is sensitive to the acoustic features of the auditory object and reflects a process of matching them with target categories. The F-complex and MMN reflect different aspects of auditory processing in a stimulus-rich and changing environment: content analysis of the stimulus and novelty detection, respectively.

Optical contacting for gravity probe star tracker

NASA Technical Reports Server (NTRS)

Wright, J. J.; Zissa, D. E.

1984-01-01

A star-tracker telescope, constructed entirely of fused silica elements optically contacted together, has been proposed to provide submilliarc-second pointing accuracy for Gravity Probe. A bibliography and discussion on optical contacting (the bonding of very flat, highly polished surfaces without the use of adhesives) are presented. Then results from preliminary experiments on the strength of optical contacts including a tensile strength test in liquid helium are discussed. Suggestions are made for further study to verify an optical contacting method for the Gravity Probe star-tracker telescope.

Effectively selling astronomy to the public -- fusing lessons learned from education, entertainment, advertising and public relations

NASA Astrophysics Data System (ADS)

Pallone, Arthur; Day, Jacque

2010-03-01

A great celestial story is only as effective as the teller of the tale. With passion and knowledge at the helm, we must search for ways to pass on enthusiasm to others while conveying sound science. Based on our experiences, we present an integrated approach -- one that borrows elements from education, entertainment, advertising, and public relations -- to choose an event, hook and keep the public's attention while making them want more, and provide some tips for increasing media presence.

Studies of the Mu-Opioid Receptor/G-protein Complex Affinity Co-Purified and Membrane Preparations from 7315c Cells

DTIC Science & Technology

1989-06-09

centrifugational sedimentation rates of the GTPys- activated and inactivated purified Gs (Birnbaumer et al., 1985). Recently, different antibodies raised against...and Membrane Preparations from 7315c Cells 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e...were shown to be fused with the 1 membranes from turkey erythrocytes that have ~-adrenergic receptors but inactive adenylyl cyclase activity due to

Process for producing elements from a fused bath using a metal strap and ceramic electrode body nonconsumable electrode assembly

DOEpatents

Byrne, Stephen C.

1984-01-01

A nonconsumable electrode assembly suitable for use in the production of metal by electrolytic reduction of a metal compound dissolved in a molten salt, the assembly comprising a ceramic electrode body and a metal subassembly of a metal conductor rod and at least one metal strap affixed to an end of the rod with opposing portions extending radially outwardly from the rod axis and having the ends of the strap attached to the electrode body.

An Experimental Investigation of the Long-Term Stability of Triple-Point-of-Water Cells

NASA Astrophysics Data System (ADS)

Hill, K. D.

2014-04-01

Contamination of triple-point-of-water (TPW) cells by the chemical components of the borosilicate glass that contains the water is now widely recognized as the principal contributor to long-term drift of the cell temperature. To add to the available experimental data, a comparison of 24 TPW cells of various ages (from 10 years to 59 years), manufacturers (NRC, Jarrett, Isotech), and materials (borosilicate glass and fused quartz) was undertaken in 2013. Twelve cells from this group were compared to one another in 1997. By comparing the current inter-cell temperature differences to those determined 16 years earlier, it was found that some cells have remained stable, others have become colder (as might be expected from ongoing dissolution of the glass), and one or two show an apparent increase in temperature that seems anomalous. Also included among the 24 cells are five cells of borosilicate glass and five of fused quartz that were purchased 10 years ago. By comparing the relative temperature differences among this group of borosilcate and fused-quartz-encapsulated cells to the values obtained when they were last compared 6 years ago, it was found that the average temperature of the borosilcate group of cells decreases by , in reasonable agreement with an average drift of suggested 12 years ago. It was concluded that fused quartz is the superior container for TPW cells.

Particle damage sources for fused silica optics and their mitigation on high energy laser systems.

PubMed

Bude, J; Carr, C W; Miller, P E; Parham, T; Whitman, P; Monticelli, M; Raman, R; Cross, D; Welday, B; Ravizza, F; Suratwala, T; Davis, J; Fischer, M; Hawley, R; Lee, H; Matthews, M; Norton, M; Nostrand, M; VanBlarcom, D; Sommer, S

2017-05-15

High energy laser systems are ultimately limited by laser-induced damage to their critical components. This is especially true of damage to critical fused silica optics, which grows rapidly upon exposure to additional laser pulses. Much progress has been made in eliminating damage precursors in as-processed fused silica optics (the advanced mitigation process, AMP3), and very high damage resistance has been demonstrated in laboratory studies. However, the full potential of these improvements has not yet been realized in actual laser systems. In this work, we explore the importance of additional damage sources-in particular, particle contamination-for fused silica optics fielded in a high-performance laser environment, the National Ignition Facility (NIF) laser system. We demonstrate that the most dangerous sources of particle contamination in a system-level environment are laser-driven particle sources. In the specific case of the NIF laser, we have identified the two important particle sources which account for nearly all the damage observed on AMP3 optics during full laser operation and present mitigations for these particle sources. Finally, with the elimination of these laser-driven particle sources, we demonstrate essentially damage free operation of AMP3 fused silica for ten large optics (a total of 12,000 cm 2 of beam area) for shots from 8.6 J/cm 2 to 9.5 J/cm 2 of 351 nm light (3 ns Gaussian pulse shapes). Potentially many other pulsed high energy laser systems have similar particle sources, and given the insight provided by this study, their identification and elimination should be possible. The mitigations demonstrated here are currently being employed for all large UV silica optics on the National Ignition Facility.

Fundamental study of FC-72 pool boiling surface temperature fluctuations and bubble behavior

NASA Astrophysics Data System (ADS)

Griffin, Alison R.

A heater designed to monitor surface temperature fluctuations during pool boiling experiments while the bubbles were simultaneously being observed has been fabricated and tested. The heat source was a transparent indium tin oxide (ITO) layer commercially deposited on a fused quartz substrate. Four copper-nickel thin film thermocouples (TFTCs) on the heater surface measured the surface temperature, while a thin layer of sapphire or fused silica provided electrical insulation between the TFTCs and the ITO. The TFTCs were micro-fabricated using the liftoff process to deposit the nickel and copper metal films. The TFTC elements were 50 mum wide and overlapped to form a 25 mum by 25 mum junction. TFTC voltages were recorded by a DAQ at a sampling rate of 50 kHz. A high-speed CCD camera recorded bubble images from below the heater at 2000 frames/second. A trigger sent to the camera by the DAQ synchronized the bubble images and the surface temperature data. As the bubbles and their contact rings grew over the TFTC junction, correlations between bubble behavior and surface temperature changes were demonstrated. On the heaters with fused silica insulation layers, 1--2°C temperature drops on the order of 1 ms occurred as the contact ring moved over the TFTC junction during bubble growth and as the contact ring moved back over the TFTC junction during bubble departure. These temperature drops during bubble growth and departure were due to microlayer evaporation and liquid rewetting the heated surface, respectively. Microlayer evaporation was not distinguished as the primary method of heat removal from the surface. Heaters with sapphire insulation layers did not display the measurable temperature drops observed with the fused silica heaters. The large thermal diffusivity of the sapphire compared to the fused silica was determined as the reason for the absence of these temperature drops. These findings were confirmed by a comparison of temperature drops in a 2-D simulation of a bubble growing over the TFTC junction on both the sapphire and fused silica heater surfaces. When the fused silica heater produced a temperature drop of 1.4°C, the sapphire heater produced a drop of only 0.04°C under the same conditions. These results verified that the lack of temperature drops present in the sapphire data was due to the thermal properties of the sapphire layer. By observing the bubble departure frequency and site density on the heater, as well as the bubble departure diameter, the contribution of nucleate boiling to the overall heat removal from the surface could be calculated. These results showed that bubble vapor generation contributed to approximately 10% at 1 W/cm2, 23% at 1.75 W/cm2, and 35% at 2.9 W/cm 2 of the heat removed from a fused silica heater. Bubble growth and contact ring growth were observed and measured from images obtained with the high-speed camera. Bubble data recorded on a fused silica heater at 3 W/cm2, 4 W/cm2, and 5 W/cm 2 showed that bubble departure diameter and lifetime were negligibly affected by the increase in heat flux. Bubble and contact ring growth rates demonstrated significant differences when compared on the fused silica and sapphire heaters at 3 W/cm2. The bubble departure diameters were smaller, the bubble lifetimes were longer, and the bubble departure frequency was larger on the sapphire heater, while microlayer evaporation was faster on the fused silica heater. Additional considerations revealed that these differences may be due to surface conditions as well as differing thermal properties. Nucleate boiling curves were recorded on the fused silica and sapphire heaters by adjusting the heat flux input and monitoring the local surface temperature with the TFTCs. The resulting curves showed a temperature drop at the onset of nucleate boiling due to the increase in heat transfer coefficient associated with bubble nucleation. One of the TFTC locations on the sapphire heater frequently experienced a second temperature drop at a higher heat flux. When the heat flux was started from 1 W/cm2 instead of zero or returned to zero only momentarily, the temperature overshoot did not occur. In these cases sufficient vapor remained in the cavities to initiate boiling at a lower superheat.

Self-healing fuse development

NASA Technical Reports Server (NTRS)

Jones, N. D.; Kinsinger, R. E.; Harris, L. P.

1973-01-01

The mercury-filled self-healing fuses developed for this program afford very good protection from circuit faults with rapid reclosure. Fuse performance and design parameters have been characterized. Life tests indicate a capability of 500 fuse operations. Fuse ratings are 150 v at 5, 15, 25 and 50 circuit A. A series of sample fuses using alumina and beryllia insulation have been furnished to NASA for circuit evaluation.

Role of G protein-coupled estrogen receptor-1 in estradiol 17β-induced alterations in protein synthesis and protein degradation rates in fused bovine satellite cell cultures.

PubMed

Kamanga-Sollo, E; Thornton, K J; White, M E; Dayton, W R

2017-01-01

In feedlot steers, estradiol-17β (E2) and combined E2 and trenbolone acetate (a testosterone analog) implants enhance rate and efficiency of muscle growth; and, consequently, these compounds are widely used as growth promoters in several countries. Treatment with E2 stimulates protein synthesis rate and suppresses protein degradation rate in fused bovine satellite cell (BSC) cultures; however, the mechanisms involved in these effects are not known with certainty. Although the genomic effects of E2 mediated through the classical estrogen receptors have been characterized, recent studies indicate that binding of E2 to the G protein-coupled estrogen receptor (GPER)-1 mediates nongenomic effects of E2 on cellular function. Our current data show that inhibition of GPER-1, matrix metalloproteinases 2 and 9 (MMP2/9), or heparin binding epidermal growth factor-like growth factor (hbEGF) suppresses E2 stimulate protein synthesis rate in cultured BSCs (P < 0.001) suggesting that all of these are required in order for E2 to stimulate protein synthesis in these cultures. In contrast, inhibition of GPER-1, MMP2/9, or hbEGF has no effect on the ability of E2 to suppress protein degradation rates in fused BSC cultures indicating that these factors are not required in order for E2 to suppress protein degradation rate in these cells. Furthermore, treatment of fused BSC cultures with E2 increased (P < 0.05) pAKT levels indicating that the pAKT pathway may play a role in E2-stimulated effects on cultured BSC. In summary, our current data show that active GPER-1, MMP2/9, and hbEGF are necessary for E2-stimulated protein synthesis but not for E2-simulated suppression of protein degradation in cultured BSC. In addition, E2 treatment increases pAKT levels in cultured BSC. Copyright © 2016 Elsevier Inc. All rights reserved.

Effects of space-radiation damage and temperature on CCD noise for the Lyman FUSE mission

NASA Astrophysics Data System (ADS)

Murowinski, Richard G.; Gao, Linzhuang; Deen, Mohamed J.

1993-09-01

Charge coupled device (CCD) imaging arrays are becoming more frequently used in space vehicles and equipment, especially space-based astronomical telescopes. It is important to understand the effects of radiation on a CCD so that its performance degradation during mission lifetime can be predicted, and so that methods to prevent unacceptable performance degradation can be found. Much recent work by various groups has focused on the problems surrounding the loss of charge transfer efficiency and the increase in dark current and dark current spikes in CCDs. The use of a CCD as the fine error sensor in the Lyman Far Ultraviolet Spectroscopic Explorer (FUSE) is limited by its noise performance. In this work we attempt to understand some of the factors surrounding the noise degradation due to radiation in a space environment. Later, we demonstrate how low frequency noise can be used as a characterization tool for studying proton radiation damage in CCDs.

Actors and networks in resource conflict resolution under climate change in rural Kenya

NASA Astrophysics Data System (ADS)

Ngaruiya, Grace W.; Scheffran, Jürgen

2016-05-01

The change from consensual decision-making arrangements into centralized hierarchical chieftaincy schemes through colonization disrupted many rural conflict resolution mechanisms in Africa. In addition, climate change impacts on land use have introduced additional socio-ecological factors that complicate rural conflict dynamics. Despite the current urgent need for conflict-sensitive adaptation, resolution efficiency of these fused rural institutions has hardly been documented. In this context, we analyse the Loitoktok network for implemented resource conflict resolution structures and identify potential actors to guide conflict-sensitive adaptation. This is based on social network data and processes that are collected using the saturation sampling technique to analyse mechanisms of brokerage. We find that there are three different forms of fused conflict resolution arrangements that integrate traditional institutions and private investors in the community. To effectively implement conflict-sensitive adaptation, we recommend the extension officers, the council of elders, local chiefs and private investors as potential conduits of knowledge in rural areas. In conclusion, efficiency of these fused conflict resolution institutions is aided by the presence of holistic resource management policies and diversification in conflict resolution actors and networks.

Low-jitter high-power thyristor array pulse driver and generator

DOEpatents

Hanks, Roy L.

2002-01-01

A method and apparatus for generating low-jitter, high-voltage and high-current pulses for driving low impedance loads such as detonator fuses uses a MOSFET driver which, when triggered, discharges a high-voltage pre-charged capacitor into the primary of a toroidal current-multiplying transformer with multiple isolated secondary windings. The secondary outputs are suitable for driving an array of thyristors that discharge a precharged high-voltage capacitor and thus generating the required high-voltage and high-current pulse.

Materials Testing and Cost Modeling for Composite Parts Through Additive Manufacturing

DTIC Science & Technology

2016-04-30

FDM include plastic jet printing (PJP), fused filament modeling ( FFM ), and fused filament fabrication (FFF). FFF was coined by the RepRap project to...additive manufacturing processes? • Fused deposition modeling (FDM) trademarked by Stratasys • Fused filament modeling ( FFM ) and fused filament

Usefulness of 2D fusion of postmortem CT and antemortem chest radiography studies for human identification.

PubMed

Shinkawa, Norihiro; Hirai, Toshinori; Nishii, Ryuichi; Yukawa, Nobuhiro

2017-06-01

To determine the feasibility of human identification through the two-dimensional (2D) fusion of postmortem computed tomography (PMCT) and antemortem chest radiography. The study population consisted of 15 subjects who had undergone chest radiography studies more than 12 months before death. Fused images in which a chest radiograph was fused with a PMCT image were obtained for those subjects using a workstation, and the minimum distance gaps between corresponding anatomical landmarks (located at soft tissue and bone sites) in the images obtained with the two modalities were calculated. For each fused image, the mean of all these minimum distance gaps was recorded as the mean distance gap (MDG). For each subject, the MDG obtained for the same-subject fused image (i.e., where both of the images that were fused derived from that subject) was compared with the MDGs for different-subject fused images (i.e., where only one of the images that were fused derived from that subject; the other image derived from a different subject) in order to determine whether same-subject fused images can be reliably distinguished from different-subject fused images. The MDGs of the same-subject fused images were found to be significantly smaller than the MDGs of the different-subject fused images (p < 0.01). When bone landmarks were used, the same-subject fused image was found to be the fused image with the lowest MDG for 33.3% of the subjects, the fused image with the lowest or second-lowest MDG for 73.3% of the subjects, and the fused image with the lowest, second-lowest, or third-lowest MDG for 86.7% of the subjects. The application of bone landmarks rather than soft-tissue landmarks made it significantly more likely that, for each subject, the same-subject fused image would have the lowest MDG (or one of the lowest MDGs) of all the fused images compared (p < 0.05). The 2D fusion of antemortem chest radiography and postmortem CT images may assist in human identification.

30 CFR 28.22 - Notice of disapproval.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Notice of disapproval. 28.22 Section 28.22 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR...

Study of robot landmark recognition with complex background

NASA Astrophysics Data System (ADS)

Huang, Yuqing; Yang, Jia

2007-12-01

It's of great importance for assisting robot in path planning, position navigating and task performing by perceiving and recognising environment characteristic. To solve the problem of monocular-vision-oriented landmark recognition for mobile intelligent robot marching with complex background, a kind of nested region growing algorithm which fused with transcendental color information and based on current maximum convergence center is proposed, allowing invariance localization to changes in position, scale, rotation, jitters and weather conditions. Firstly, a novel experiment threshold based on RGB vision model is used for the first image segmentation, which allowing some objects and partial scenes with similar color to landmarks also are detected with landmarks together. Secondly, with current maximum convergence center on segmented image as each growing seed point, the above region growing algorithm accordingly starts to establish several Regions of Interest (ROI) orderly. According to shape characteristics, a quick and effectual contour analysis based on primitive element is applied in deciding whether current ROI could be reserved or deleted after each region growing, then each ROI is judged initially and positioned. When the position information as feedback is conveyed to the gray image, the whole landmarks are extracted accurately with the second segmentation on the local image that exclusive to landmark area. Finally, landmarks are recognised by Hopfield neural network. Results issued from experiments on a great number of images with both campus and urban district as background show the effectiveness of the proposed algorithm.

RUBE: an XML-based architecture for 3D process modeling and model fusion

NASA Astrophysics Data System (ADS)

Fishwick, Paul A.

2002-07-01

Information fusion is a critical problem for science and engineering. There is a need to fuse information content specified as either data or model. We frame our work in terms of fusing dynamic and geometric models, to create an immersive environment where these models can be juxtaposed in 3D, within the same interface. The method by which this is accomplished fits well into other eXtensible Markup Language (XML) approaches to fusion in general. The task of modeling lies at the heart of the human-computer interface, joining the human to the system under study through a variety of sensory modalities. I overview modeling as a key concern for the Defense Department and the Air Force, and then follow with a discussion of past, current, and future work. Past work began with a package with C and has progressed, in current work, to an implementation in XML. Our current work is defined within the RUBE architecture, which is detailed in subsequent papers devoted to key components. We have built RUBE as a next generation modeling framework using our prior software, with research opportunities in immersive 3D and tangible user interfaces.

Effect of annealing on the laser induced damage of polished and CO2 laser-processed fused silica surfaces

NASA Astrophysics Data System (ADS)

Doualle, T.; Gallais, L.; Cormont, P.; Donval, T.; Lamaignère, L.; Rullier, J. L.

2016-06-01

We investigate the effect of different heat treatments on the laser-induced damage probabilities of fused silica samples. Isothermal annealing in a furnace is applied, with different temperatures in the range 700-1100 °C and 12 h annealing time, to super-polished fused silica samples. The surface flatness and laser damage probabilities at 3 ns, 351 nm are measured before and after the different annealing procedures. We have found a significant improvement of the initial laser damage probabilities of the silica surface after annealing at 1050 °C for 12 h. A similar study has been conducted on CO2 laser-processed sites on the surface of the samples. Before and after annealing, we have studied the morphology of the sites, the evolution of residual stress, and the laser-induced damage threshold measured at 351 nm, 3 ns. In this case, we observe that the laser damage resistance of the laser created craters can reach the damage level of the bare fused silica surface after the annealing process, with a complete stress relieve. The obtained results are then compared to the case of local annealing process by CO2 laser irradiation during 1 s, and we found similar improvements in both cases. The different results obtained in the study are compared to numerical simulations made with a thermo-mechanical model based on finite-element method that allows the simulation of the isothermal or the local annealing process, the evolution of stress and fictive temperature. The simulation results were found to be very consistent with experimental observations for the stresses evolution after annealing and estimation of the heat affected area during laser-processing based on the density dependence with fictive temperature. Following this work, the temperature for local annealing should reach 1330-1470 °C for an optimized reduction of damage probability and be below the threshold for material removal, whereas furnace annealing should be kept below the annealing point to avoid sample deformation.

Method for removing sulfur oxide from waste gases and recovering elemental sulfur

DOEpatents

Moore, Raymond H.

1977-01-01

A continuous catalytic fused salt extraction process is described for removing sulfur oxides from gaseous streams. The gaseous stream is contacted with a molten potassium sulfate salt mixture having a dissolved catalyst to oxidize sulfur dioxide to sulfur trioxide and molten potassium normal sulfate to solvate the sulfur trioxide to remove the sulfur trioxide from the gaseous stream. A portion of the sulfur trioxide loaded salt mixture is then dissociated to produce sulfur trioxide gas and thereby regenerate potassium normal sulfate. The evolved sulfur trioxide is reacted with hydrogen sulfide as in a Claus reactor to produce elemental sulfur. The process may be advantageously used to clean waste stack gas from industrial plants, such as copper smelters, where a supply of hydrogen sulfide is readily available.

Solid-Body Fuse Developed for High- Voltage Space Power Missions

NASA Technical Reports Server (NTRS)

Dolce, James L.; Baez, Anastacio N.

2001-01-01

AEM Incorporated has completed the development, under a NASA Glenn Research Center contract, of a solid-body fuse for high-voltage power systems of satellites and spacecraft systems. High-reliability fuses presently defined by MIL-PRF-23419 do not meet the increased voltage and amperage requirements for the next generation of spacecraft. Solid-body fuses exhibit electrical and mechanical attributes that enable these fuses to perform reliably in the vacuum and high-vibration and -shock environments typically present in spacecraft applications. The construction and screening techniques for solid-body fuses described by MIL-PRF-23419/12 offer an excellent roadmap for the development of high-voltage solid-body fuses.

Multivariate classification of edible salts: Simultaneous Laser-Induced Breakdown Spectroscopy and Laser-Ablation Inductively Coupled Plasma Mass Spectrometry Analysis

NASA Astrophysics Data System (ADS)

Lee, Yonghoon; Nam, Sang-Ho; Ham, Kyung-Sik; Gonzalez, Jhanis; Oropeza, Dayana; Quarles, Derrick; Yoo, Jonghyun; Russo, Richard E.

2016-04-01

Laser-Induced Breakdown Spectroscopy (LIBS) and Laser-Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS), both based on laser ablation sampling, can be employed simultaneously to obtain different chemical fingerprints from a sample. We demonstrated that this analysis approach can provide complementary information for improved classification of edible salts. LIBS could detect several of the minor metallic elements along with Na and Cl, while LA-ICP-MS spectra were used to measure non-metallic and trace heavy metal elements. Principal component analysis using LIBS and LA-ICP-MS spectra showed that their major spectral variations classified the sample salts in different ways. Three classification models were developed by using partial least squares-discriminant analysis based on the LIBS, LA-ICP-MS, and their fused data. From the cross-validation performances and confusion matrices of these models, the minor metallic elements (Mg, Ca, and K) detected by LIBS and the non-metallic (I) and trace heavy metal (Ba, W, and Pb) elements detected by LA-ICP-MS provided complementary chemical information to distinguish particular salt samples.

33 CFR 183.455 - Overcurrent protection: General.

Code of Federal Regulations, 2011 CFR

2011-07-01

....455 Overcurrent protection: General. (a) Each ungrounded current-carrying conductor must be protected... breaker or fuse must be placed at the source of power for each circuit or conductor except: (1) If it is... seven inches of the source of power for each circuit or conductor measured along the conductor. (2) If...

33 CFR 183.455 - Overcurrent protection: General.

Code of Federal Regulations, 2010 CFR

2010-07-01

....455 Overcurrent protection: General. (a) Each ungrounded current-carrying conductor must be protected... breaker or fuse must be placed at the source of power for each circuit or conductor except: (1) If it is... seven inches of the source of power for each circuit or conductor measured along the conductor. (2) If...

30 CFR 28.24 - Revocation of certificates of approval.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Revocation of certificates of approval. 28.24 Section 28.24 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT...

30 CFR 28.20 - Certificates of approval; scope of approval.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Certificates of approval; scope of approval. 28.20 Section 28.20 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT...

Y-Trap Cancer Immunotherapy Drug Targets Two Proteins

Cancer.gov

Two groups of researchers, working independently, have fused a TGF-beta receptor to a monoclonal antibody that targets a checkpoint protein. The result, this Cancer Currents blog describes, is a single hybrid molecule called a Y-trap that blocks two pathways used by tumors to evade the immune system.

Functional dissection of a napin gene promoter: identification of promoter elements required for embryo and endosperm-specific transcription.

PubMed

Ellerström, M; Stålberg, K; Ezcurra, I; Rask, L

1996-12-01

The promoter region (-309 to +44) of the Brassica napus storage protein gene napA was studied in transgenic tobacco by successive 5' as well as internal deletions fused to the reporter gene GUS (beta-glucuronidase). The expression in the two main tissues of the seed, the endosperm and the embryo, was shown to be differentially regulated. This tissue-specific regulation within the seed was found to affect the developmental expression during seed development. The region between -309 to -152, which has a large effect on quantitative expression, was shown to harbour four elements regulating embryo and one regulating endosperm expression. This region also displayed enhancer activity. Deletion of eight bp from position -152 to position -144 totally abolished the activity of the napA promoter. This deletion disrupted a cis element with similarity to an ABA-responsive element (ABRE) overlapping with an E-box, demonstrating its crucial importance for quantitative expression. An internal deletion of the region -133 to -120, resulted in increased activity in both leaves and endosperm and a decreased activity in the embryo. Within this region, a cis element similar to the (CA)n element, found in other storage protein promoters, was identified. This suggest that the (CA)n element is important for conferring seed specificity by serving both as an activator and a repressor element.

Data fusion for food authentication. Combining rare earth elements and trace metals to discriminate "Fava Santorinis" from other yellow split peas using chemometric tools.

PubMed

Drivelos, Spiros A; Higgins, Kevin; Kalivas, John H; Haroutounian, Serkos A; Georgiou, Constantinos A

2014-12-15

"Fava Santorinis", is a protected designation of origin (PDO) yellow split pea species growing only in the island of Santorini in Greece. Due to its nutritional quality and taste, it has gained a high monetary value. Thus, it is prone to adulteration with other yellow split peas. In order to discriminate "Fava Santorinis" from other yellow split peas, four classification methods utilising rare earth elements (REEs) measured through inductively coupled plasma-mass spectrometry (ICP-MS) are studied. The four classification processes are orthogonal projection analysis (OPA), Mahalanobis distance (MD), partial least squares discriminant analysis (PLS-DA) and k nearest neighbours (KNN). Since it is known that trace elements are often useful to determine geographical origin of food products, we further quantitated for trace elements using ICP-MS. Presented in this paper are results using the four classification processes based on the fusion of the REEs data with the trace element data. Overall, the OPA method was found to perform best with up to 100% accuracy using the fused data. Copyright © 2014 Elsevier Ltd. All rights reserved.

CT evaluation of timing for ossification of the medial clavicular epiphysis in a contemporary Western Australian population.

PubMed

Franklin, Daniel; Flavel, Ambika

2015-05-01

The clavicle is the first bone to ossify in the developing embryo and the last to complete epiphyseal union. It is the latter sustained period of growth that has attracted the interest of skeletal biologists and forensic practitioners alike, who collectively recognize the important opportunity this bone affords to estimate skeletal age across the prenatal to early adult lifespan. Current research is largely directed towards evaluating the applicability of assessing fusion in the medial epiphysis, specifically for determining age of majority in the living. This study aims to contribute further insights, and inform medicolegal practice, by evaluating the Schmeling five-stage system for the assessment of clavicular development in a Western Australian population. We retrospectively evaluated high-resolution multiple detector computed tomography (MDCT) scans of 388 individuals (210 male; 178 female) between 10 and 35 years of age. Scans are viewed in axial and multiplanar reconstructed (MPR) images using OsiriX®. Fusion status is scored according to a five-stage system. Transition analysis is used to calculate age ranges and determine the mean age for transition between an unfused, fusing and fused status. The maximum likelihood estimates (in years) for transition from unfused to fusing is 20.60 (male) and 19.19 (female); transition from fusing to complete fusion is 21.92 (male) and 21.47 (female). Results of the present study confirm the reliability of the assessed method and demonstrate remarkable consistency to data reported for other global populations.

METHOD OF SEPARATING FISSION PRODUCTS FROM FUSED BISMUTH-CONTAINING URANIUM

DOEpatents

Wiswall, R.H.

1958-06-24

A process is described for removing metal selectively from liquid metal compositions. The method effects separation of flssion product metals selectively from dilute solution in fused bismuth, which contains uraniunn in solution without removal of more than 1% of the uranium. The process comprises contacting the fused bismuth with a fused salt composition consisting of sodium, potassium and lithium chlorides, adding to fused bismuth and molten salt a quantity of bismuth chloride which is stoichiometrically required to convert the flssion product metals to be removed to their chlorides which are more stable in the fused salt than in the molten metal and are, therefore, preferentially taken up in the fused salt phase.

A promising anti-cancer and anti-oxidant agents based on the pyrrole and fused pyrrole: synthesis, docking studies and biological evaluation.

PubMed

Fatahala, Samar Said; Shalaby, Emad Ahmed; Kassab, Shaymaa Emam; Mohamed, Mossad Said

2015-01-01

A series of N-aryl derivatives of pyrrole and its related derivatives of fused form (namely; tetrahydroindole and dihydroindenopyrroles) were prepared in fair to good yields. The newly synthesized compounds were confirmed using IR, (1)H NMR, Mass spectral and elemental analysis. Tetrahydrobenzo[b] pyrroles Ia-d, 1,4-dihydroindeno[1,2-b]pyrroles IIa,b and pyrroles IIIa-c,e were evaluated for anticancer activity, coinciding with the antioxidant activity; using Di-Phenyl Picryl Hydrazyl (DPPH) tests. The cytotoxicity of the tested compounds (at a concentration of 100 and 200 μg /mL) was performed against HepG-2 and EACC cell lines. Compounds Ib, d and IIa showed promising antioxidant activity beside their anticancer activity. Docking studies were employed to justify the promising anticancer activity of Ib,d and IIa. Protein kinase (PKase)-PDB entry 1FCQ was chosen as target enzyme for this purpose using the MOLSOFT ICM 3.4-8C program. The docking results of the tested compounds went aligned with the respective anticancer assay results.

In vivo blunt-end cloning through CRISPR/Cas9-facilitated non-homologous end-joining

PubMed Central

Geisinger, Jonathan M.; Turan, Sören; Hernandez, Sophia; Spector, Laura P.; Calos, Michele P.

2016-01-01

The CRISPR/Cas9 system facilitates precise DNA modifications by generating RNA-guided blunt-ended double-strand breaks. We demonstrate that guide RNA pairs generate deletions that are repaired with a high level of precision by non-homologous end-joining in mammalian cells. We present a method called knock-in blunt ligation for exploiting these breaks to insert exogenous PCR-generated sequences in a homology-independent manner without loss of additional nucleotides. This method is useful for making precise additions to the genome such as insertions of marker gene cassettes or functional elements, without the need for homology arms. We successfully utilized this method in human and mouse cells to insert fluorescent protein cassettes into various loci, with efficiencies up to 36% in HEK293 cells without selection. We also created versions of Cas9 fused to the FKBP12-L106P destabilization domain in an effort to improve Cas9 performance. Our in vivo blunt-end cloning method and destabilization-domain-fused Cas9 variant increase the repertoire of precision genome engineering approaches. PMID:26762978

Cryptic Amyloidogenic Elements in the 3′ UTRs of Neurofilament Genes Trigger Axonal Neuropathy

PubMed Central

Rebelo, Adriana P.; Abrams, Alexander J.; Cottenie, Ellen; Horga, Alejandro; Gonzalez, Michael; Bis, Dana M.; Sanchez-Mejias, Avencia; Pinto, Milena; Buglo, Elena; Markel, Kasey; Prince, Jeffrey; Laura, Matilde; Houlden, Henry; Blake, Julian; Woodward, Cathy; Sweeney, Mary G.; Holton, Janice L.; Hanna, Michael; Dallman, Julia E.; Auer-Grumbach, Michaela; Reilly, Mary M.; Zuchner, Stephan

2016-01-01

Abnormal protein aggregation is observed in an expanding number of neurodegenerative diseases. Here, we describe a mechanism for intracellular toxic protein aggregation induced by an unusual mutation event in families affected by axonal neuropathy. These families carry distinct frameshift variants in NEFH (neurofilament heavy), leading to a loss of the terminating codon and translation of the 3′ UTR into an extra 40 amino acids. In silico aggregation prediction suggested the terminal 20 residues of the altered NEFH to be amyloidogenic, which we confirmed experimentally by serial deletion analysis. The presence of this amyloidogenic motif fused to NEFH caused prominent and toxic protein aggregates in transfected cells and disrupted motor neurons in zebrafish. We identified a similar aggregation-inducing mechanism in NEFL (neurofilament light) and FUS (fused in sarcoma), in which mutations are known to cause aggregation in Charcot-Marie-Tooth disease and amyotrophic lateral sclerosis, respectively. In summary, we present a protein-aggregation-triggering mechanism that should be taken into consideration during the evaluation of stop-loss variants. PMID:27040688

Joining Dental Ceramic Layers With Glass

PubMed Central

Saied, MA; Lloyd, IK; Haller, WK; Lawn, BR

2011-01-01

Objective Test the hypothesis that glass-bonding of free-form veneer and core ceramic layers can produce robust interfaces, chemically durable and aesthetic in appearance and, above all, resistant to delamination. Methods Layers of independently produced porcelains (NobelRondo™ Press porcelain, Nobel BioCare AB and Sagkura Interaction porcelain, Elephant Dental) and matching alumina or zirconia core ceramics (Procera alumina, Nobel BioCare AB, BioZyram yttria stabilized tetragonal zirconia polycrystal, Cyrtina Dental) were joined with designed glasses, tailored to match thermal expansion coefficients of the components and free of toxic elements. Scanning electron microprobe analysis was used to characterize the chemistry of the joined interfaces, specifically to confirm interdiffusion of ions. Vickers indentations were used to drive controlled corner cracks into the glass interlayers to evaluate the toughness of the interfaces. Results The glass-bonded interfaces were found to have robust integrity relative to interfaces fused without glass, or those fused with a resin-based adhesive. Significance The structural integrity of the interfaces between porcelain veneers and alumina or zirconia cores is a critical factor in the longevity of all-ceramic dental crowns and fixed dental prostheses. PMID:21802131

Process for producing elements from a fused bath using a metal strap and ceramic electrode body nonconsumable electrode assembly

DOEpatents

Byrne, S.C.

1984-07-03

A nonconsumable electrode assembly is described suitable for use in the production of metal by electrolytic reduction of a metal compound dissolved in a molten salt, the assembly comprising a ceramic electrode body and a metal subassembly of a metal conductor rod and at least one metal strap affixed to an end of the rod with opposing portions extending radially outwardly from the rod axis and having the ends of the strap attached to the electrode body. 7 figs.

[Measuring microhardness of laser exposed tooth surface].

PubMed

Florin, R; Herrmann, C; Bernhardt, W

1990-02-01

In principle it is possible to homogenize the enamel surface by melting structural elements with the continuous wave CO2 laser. Using the precision instrument NEOPHOT 2 (Carl Zeiss JENA) the microhardness of extracted laserexposed premolares were tested so as to clarify the functional strain capasity and the mechanical characteristics of laserexposed regions of enamel surfaces. The proven higher hardness in the centre of the laserinduced fusing zones (in comparison with adjacent enamel) objectify an attainable refining of the enamel surface that probably causes an increase in the caries-preventive resistance.

Incipient Fault Detection for Rolling Element Bearings under Varying Speed Conditions.

PubMed

Xue, Lang; Li, Naipeng; Lei, Yaguo; Li, Ningbo

2017-06-20

Varying speed conditions bring a huge challenge to incipient fault detection of rolling element bearings because both the change of speed and faults could lead to the amplitude fluctuation of vibration signals. Effective detection methods need to be developed to eliminate the influence of speed variation. This paper proposes an incipient fault detection method for bearings under varying speed conditions. Firstly, relative residual (RR) features are extracted, which are insensitive to the varying speed conditions and are able to reflect the degradation trend of bearings. Then, a health indicator named selected negative log-likelihood probability (SNLLP) is constructed to fuse a feature set including RR features and non-dimensional features. Finally, based on the constructed SNLLP health indicator, a novel alarm trigger mechanism is designed to detect the incipient fault. The proposed method is demonstrated using vibration signals from bearing tests and industrial wind turbines. The results verify the effectiveness of the proposed method for incipient fault detection of rolling element bearings under varying speed conditions.

Cap-independent translation of poliovirus mRNA is conferred by sequence elements within the 5' noncoding region

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pelletier, J.; Kaplan, G.; Racaniello, V.R.

1988-03-01

Poliovirus polysomal RNA is naturally uncapped, and as such, its translation must bypass any 5' cap-dependent ribosome recognition event. To elucidate the manner by which poliovirus mRNA is translated, the authors determined the translational efficiencies of a series of deletion mutants within the 5' noncoding region of the mRNA. They found striking differences in translatability among the altered mRNAs when assayed in mock-infected and poliovirus-infected HeLa cell extracts. The results identify a functional cis-acting element within the 5' noncoding region of the poliovirus mRNA which enables it to translate in a cap-independent fashion. The major determinant of this element mapsmore » between nucleotides 320 and 631 of the 5' end of the poliovirus mRNA. They also show that this region (320 to 631), when fused to a heterologous mRNA, can function in cis to render the mRNA cap independent in translation.« less

Incipient Fault Detection for Rolling Element Bearings under Varying Speed Conditions

PubMed Central

Xue, Lang; Li, Naipeng; Lei, Yaguo; Li, Ningbo

2017-01-01

Varying speed conditions bring a huge challenge to incipient fault detection of rolling element bearings because both the change of speed and faults could lead to the amplitude fluctuation of vibration signals. Effective detection methods need to be developed to eliminate the influence of speed variation. This paper proposes an incipient fault detection method for bearings under varying speed conditions. Firstly, relative residual (RR) features are extracted, which are insensitive to the varying speed conditions and are able to reflect the degradation trend of bearings. Then, a health indicator named selected negative log-likelihood probability (SNLLP) is constructed to fuse a feature set including RR features and non-dimensional features. Finally, based on the constructed SNLLP health indicator, a novel alarm trigger mechanism is designed to detect the incipient fault. The proposed method is demonstrated using vibration signals from bearing tests and industrial wind turbines. The results verify the effectiveness of the proposed method for incipient fault detection of rolling element bearings under varying speed conditions. PMID:28773035

Geochemistry and genesis of the angrites

NASA Technical Reports Server (NTRS)

Mittlefehldt, David W.; Lindstrom, Marilyn M.

1990-01-01

The major and trace elements were analyzed in samples of LEW86010, LEW87051, and Angra dos Reis angrites were analyzed using INAA and fused-bead EMP techniques. Results suggest that all three angrites originated on a volatile-depleted (Na-poor) but oxidized parent body or on several bodies. The combination of low Na and high FeO/MnO found in these samples suggests that the extreme Na depletion was caused by parent-body outgassing during differentiation, rather than by nebular processes. It was also found that the refractory-element abundances observed in LEW86010 and LEW87051 are related via olivine control; it is suggested that LEW86010 may be a residual melt from a LEW87051-like precursor or that LEW87051 formed from a LEW86010-like precursor via olivine accumulation. On the other hand, the Angra dos Reis displayed an unusual refractory element pattern suggesting that either the angrite parent body was heterogeneous or that Angra dos Reis was formed on a parent body different from that of the other two angrites.

The Abundances of the Fe Group Elements in AV 304, an Abundance Standard in the Small Magellanic Cloud

NASA Astrophysics Data System (ADS)

Peters, Geraldine J.; Lanz, Thierry; Bouret, Jean-Claude; Proffitt, Charles R.; Adelman, Saul J.; Hubeny, Ivan

2018-06-01

AV 304 is a B0.5 IV field star in the Small Magellanic Cloud with ultra-sharp spectral lines that has emerged as an abundance standard. We have combined recent spectroscopic observations from the Cosmic Origins Spectrograph (COS) on the Hubble Space Telescope with archival data from the Far Ultraviolet Spectroscopic Explorer (FUSE) and ESO’s VLT/UVES to determine the abundances of the Fe group elements (Ti, V, Cr, Mn, Fe, Co, & Ni). The analysis was carried through using the Hubeny/Lanz NLTE programs TLUSTY/SYNSPEC. The COS observations were secured with the G130M, G160M, G185M, and G225M gratings. Combined with the FUSE data, we have achieved spectral coverage in the UV from 950 to 2400 A. Measurable lines from the Fe group, except for a very few multiplets of Fe II, III are not observed in optical spectra. The following stellar parameters were found: Teff = 27500±500 K, log g = 3.7±0.1 cm/s2, Vturb= 1±1 km/s, and v sin i = 8 ±2 km/s. The Fe abundance appears to be only slightly lower than the mean depletion in the SMC, but the other Fe group elements are underabundant by 0.3 dex or more. This study confirmed the low abundance of nitrogen (-1.25 dex relative to the solar value) that was reported by Peters & Adelman (ASP Conf. Series, 348, p. 136, 2006). Whereas the light elements are delivered to the ISM by core-collapse supernovae (CCSNe), the Fe group elements are believed to come mostly from low/intermediate mass binaries containing white dwarfs that undergo SNe Ia explosions. A single SNe Ia can deliver 0.5 solar masses of pure Fe (and maybe Mn) to the ISM compared with about 0.07 solar masses from a CCSNe. It appears that there is very little processed material from its interior in the atmosphere of AV 304 and that the star did not form from an interstellar cloud that was enriched by material from earlier supernova activity. Support from STScI grants HST-GO-14081.002 and HST-GO-13346.022, and USC’s Women in Science and Engineering (WiSE) program is greatly appreciated.

Simultaneous overpass off nadir (SOON): a method for unified calibration/validation across IEOS and GEOSS system of systems

NASA Astrophysics Data System (ADS)

Ardanuy, Philip; Bergen, Bill; Huang, Allen; Kratz, Gene; Puschell, Jeff; Schueler, Carl; Walker, Joe

2006-08-01

The US operates a diverse, evolving constellation of research and operational environmental satellites, principally in polar and geosynchronous orbits. Our current and enhanced future domestic remote sensing capability is complemented by the significant capabilities of our current and potential future international partners. In this analysis, we define "success" through the data customers' "eyes": participating in the sufficient and continuously improving satisfaction of their mission responsibilities. To successfully fuse together observations from multiple simultaneous platforms and sensors into a common, self-consistent, operational environment requires that there exist a unified calibration and validation approach. Here, we consider develop a concept for an integrating framework for absolute accuracy; long-term stability; self-consistency among sensors, platforms, techniques, and observing systems; and validation and characterization of performance. Across all systems, this is a non-trivial problem. Simultaneous Nadir Overpasses, or SNO's, provide a proven intercomparison technique: simultaneous, collocated, co-angular measurements. Many systems have off-nadir elements, or effects, that must be calibrated. For these systems, the nadir technique constrains the process. We define the term "SOON," for simultaneous overpass off nadir. We present a target architecture and sensitivity analysis for the affordable, sustainable implementation of a global SOON calibration/validation network that can deliver the much-needed comprehensive, common, self-consistent operational picture in near-real time, at an affordable cost.

[Computer aided design and manufacture of the porcelain fused to metal crown].

PubMed

Nie, Xin; Cheng, Xiaosheng; Dai, Ning; Yu, Qing; Hao, Guodong; Sun, Quanping

2009-04-01

In order to satisfy the current demand for fast and high-quality prosthodontics, we have carried out a research in the fabrication process of the porcelain fused to metal crown on molar with CAD/CAM technology. Firstly, we get the data of the surface mesh on preparation teeth through a 3D-optical grating measuring system. Then, we reconstruct the 3D-model crown with the computer-aided design software which was developed by ourselves. Finally, with the 3D-model data, we produce a metallic crown on a high-speed CNC carving machine. The result has proved that the metallic crown can match the preparation teeth ideally. The fabrication process is reliable and efficient, and the restoration is precise and steady in quality.

Structure and morphology of CdS thin films electrodeposited in fused salts

NASA Astrophysics Data System (ADS)

Markov, I.; Valova, E.; Ilieva, M.; Kristev, I.

1983-12-01

Thin films of CdS are catholically electrodeposited on copper and silver electrodes in solution of CdCl 2 and Na 2SO 3 in fused LiCl-KCl eutectic. The films consist only of the hexagonal wurtzite phase of CdS. The films grown on Cu substrates are polycrystalline without pronounced fibre texture. The films grown on Ag substrates show practically perfect (000-) texture exposing the Cd face at the film surface. Films deposited at high bath temperatures (450-500°C), low current densities (0.2-0.5 mA/cm 2) or doped with In during the growth are very smooth. From the morphological investigations it is concluded that the CdS films electrodeposited onto Ag substrates have well pronounced laminar structure.

Experimental Investigation on Cutting Characteristics in Nanometric Plunge-Cutting of BK7 and Fused Silica Glasses

PubMed Central

An, Qinglong; Ming, Weiwei; Chen, Ming

2015-01-01

Ductile cutting are most widely used in fabricating high-quality optical glass components to achieve crack-free surfaces. For ultra-precision machining of brittle glass materials, critical undeformed chip thickness (CUCT) commonly plays a pivotal role in determining the transition point from ductile cutting to brittle cutting. In this research, cutting characteristics in nanometric cutting of BK7 and fused silica glasses, including machined surface morphology, surface roughness, cutting force and specific cutting energy, were investigated with nanometric plunge-cutting experiments. The same cutting speed of 300 mm/min was used in the experiments with single-crystal diamond tool. CUCT was determined according to the mentioned cutting characteristics. The results revealed that 320 nm was found as the CUCT in BK7 cutting and 50 nm was determined as the size effect of undeformed chip thickness. A high-quality machined surface could be obtained with the undeformed chip thickness between 50 and 320 nm at ductile cutting stage. Moreover, no CUCT was identified in fused silica cutting with the current cutting conditions, and brittle-fracture mechanism was confirmed as the predominant chip-separation mode throughout the nanometric cutting operation. PMID:28788010

Experimental Investigation on Cutting Characteristics in Nanometric Plunge-Cutting of BK7 and Fused Silica Glasses.

PubMed

An, Qinglong; Ming, Weiwei; Chen, Ming

2015-03-27

Ductile cutting are most widely used in fabricating high-quality optical glass components to achieve crack-free surfaces. For ultra-precision machining of brittle glass materials, critical undeformed chip thickness (CUCT) commonly plays a pivotal role in determining the transition point from ductile cutting to brittle cutting. In this research, cutting characteristics in nanometric cutting of BK7 and fused silica glasses, including machined surface morphology, surface roughness, cutting force and specific cutting energy, were investigated with nanometric plunge-cutting experiments. The same cutting speed of 300 mm/min was used in the experiments with single-crystal diamond tool. CUCT was determined according to the mentioned cutting characteristics. The results revealed that 320 nm was found as the CUCT in BK7 cutting and 50 nm was determined as the size effect of undeformed chip thickness. A high-quality machined surface could be obtained with the undeformed chip thickness between 50 and 320 nm at ductile cutting stage. Moreover, no CUCT was identified in fused silica cutting with the current cutting conditions, and brittle-fracture mechanism was confirmed as the predominant chip-separation mode throughout the nanometric cutting operation.

TALE: a tale of genome editing.

PubMed

Zhang, Mingjie; Wang, Feng; Li, Shifei; Wang, Yan; Bai, Yun; Xu, Xueqing

2014-01-01

Transcription activator-like effectors (TALEs), first identified in Xanthomonas bacteria, are naturally occurring or artificially designed proteins that modulate gene transcription. These proteins recognize and bind DNA sequences based on a variable numbers of tandem repeats. Each repeat is comprised of a set of ∼ 34 conserved amino acids; within this conserved domain, there are usually two amino acids that distinguish one TALE from another. Interestingly, TALEs have revealed a simple cipher for the one-to-one recognition of proteins for DNA bases. Synthetic TALEs have been used to successfully target genes in a variety of species, including humans. Depending on the type of functional domain that is fused to the TALE of interest, these proteins can have diverse biological effects. For example, after binding DNA, TALEs fused to transcriptional activation domains can function as robust transcription factors (TALE-TFs), while fused to restriction endonucleases (TALENs) can cut DNA. Targeted genome editing, in theory, is capable of modifying any endogenous gene sequence of interest; this can be performed in cells or organisms, and may be applied to clinical gene-based therapies in the future. With current technologies, highly accurate, specific, and reliable gene editing cannot be achieved. Thus, recognition and binding mechanisms governing TALE biology are currently hot research areas. In this review, we summarize the major advances in TALE technology over the past several years with a focus on the interaction between TALEs and DNA, TALE design and construction, potential applications for this technology, and unique characteristics that make TALEs superior to zinc finger endonucleases. Copyright © 2013 Elsevier Ltd. All rights reserved.

29 CFR 1926.914 - Definitions applicable to this subpart.

Code of Federal Regulations, 2012 CFR

2012-07-01

... blasting caps—Caps designed to detonate at a predetermined period of time after energy is applied to the... designed for and capable of detonation from the sparks or flame from a safety fuse inserted and crimped...) Electric blasting cap—A blasting cap designed for and capable of detonation by means of an electric current...

29 CFR 1926.914 - Definitions applicable to this subpart.

Code of Federal Regulations, 2013 CFR

2013-07-01

... blasting caps—Caps designed to detonate at a predetermined period of time after energy is applied to the... designed for and capable of detonation from the sparks or flame from a safety fuse inserted and crimped...) Electric blasting cap—A blasting cap designed for and capable of detonation by means of an electric current...

29 CFR 1926.914 - Definitions applicable to this subpart.

Code of Federal Regulations, 2011 CFR

2011-07-01

... blasting caps—Caps designed to detonate at a predetermined period of time after energy is applied to the... designed for and capable of detonation from the sparks or flame from a safety fuse inserted and crimped...) Electric blasting cap—A blasting cap designed for and capable of detonation by means of an electric current...

29 CFR 1926.914 - Definitions applicable to this subpart.

Code of Federal Regulations, 2014 CFR

2014-07-01

... blasting caps—Caps designed to detonate at a predetermined period of time after energy is applied to the... designed for and capable of detonation from the sparks or flame from a safety fuse inserted and crimped...) Electric blasting cap—A blasting cap designed for and capable of detonation by means of an electric current...

30 CFR 28.32 - Proposed quality control plans; approval by MSHA.

Code of Federal Regulations, 2010 CFR

2010-07-01

... subpart shall be reviewed by MSHA to determine its effectiveness in insuring the quality of short-circuit... TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.32 Proposed quality control...

30 CFR 28.4 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Definitions. 28.4 Section 28.4 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR TRAILING CABLES IN COAL MINES General Provisions § 28.4...

Chasing Butterflies without a Net: Interpreting Cosmopolitanism

ERIC Educational Resources Information Center

Hansen, David T.

2010-01-01

In this article, I map current conceptions of cosmopolitanism and sketch distinctions between the concept and humanism and multiculturalism. The differences mirror what I take to be a central motif of cosmopolitanism: the capacity to fuse reflective openness to the new with reflective loyalty to the known. This motif invites a reconsideration of…

Current status of potential applications of repurposed Cas9 for structural and functional genomics of plants.

PubMed

Seth, Kunal; Harish

2016-11-25

Redesigned Cas9 has emerged as a tool with various applications like gene editing, gene regulation, epigenetic modification and chromosomal imaging. Target specific single guide RNA (sgRNA) can be used with Cas9 for precise gene editing with high efficiency than previously known methods. Further, nuclease-deactivated Cas9 (dCas9) can be fused with activator or repressor for activation (CRISPRa) and repression (CRISPRi) of gene expression, respectively. dCas9 fused with epigenetic modifier like methylase or acetylase further expand the scope of this technique. Fluorescent probes can be tagged to dCas9 to visualize the chromosome. Due to its wide-spread application, simplicity, accessibility, efficacy and universality, this technique is expanding the structural and functional genomic studies of plant and developing CRISPR crops. The present review focuses on current status of using repurposed Cas9 system in these various areas, with major focus on application in plants. Major challenges, concerns and future directions of using this technique are discussed in brief. Copyright © 2016 Elsevier Inc. All rights reserved.

The Study on Grinding Ratio in Form Grinding with White Fused Alumina (WA) Grinding Wheels

NASA Astrophysics Data System (ADS)

Junming, Wang; Jiong, Wang; Deyuan, Lou

2018-03-01

The study is carried out based on an experiment of form grinding spur rack with white fused alumina (WA) grinding wheels. In the experiment, SOV-3020A type tri-axial image mapper is utilized to measure the profile of the tooth space in the rack, and the curve equations between the sectional area of the tooth space and the tooth sequence under different grinding depths are established by nonlinear curve regress using software of origin8.0. Then, it deduces the prediction equations for current grinding ratio and cumulative grinding ratio under different grinding depths. The result shows that the grinding ratio is exponential decline relationship with the increase of the number of the tooth to be ground under the same grinding depth, and the decline speed is fast in the initial stage. With the increase of grinding depth, the grinding ratio increases gradually. The cumulative grinding ratio is about twice as high as the current grinding ratio. Thus, large grinding depth is generally used in rough grinding to improve grinding efficiency.

The Abundances of the Fe Group Elements in Early B Stars in the Magellanic Clouds and Our Galaxy

NASA Astrophysics Data System (ADS)

Peters, Geraldine Joan; Adelman, Saul Joseph

2015-08-01

The abundances of the Fe-peak elements (Ti, V, Cr, Mn, Fe, Co, and Ni) are of interest as they are important for assessing opacities for stellar evolution calculations, confirming theoretical calculations of explosive nucleosynthesis, and inferring the past history of supernova activity in a galaxy. FUSE FUV spectra of early B stars in the LMC and SMC and HST/STIS FUV/NUV spectra of nearby B stars in our galaxy are analyzed with the Hubeny/Lanz programs TLUSTY/SYNSPEC to determine abundance for the Fe group elements and produce a map of these abundances in the Magellanic Clouds (MC) and Magellanic Bridge (MB). Except for four weak multiplets of Fe III there are no measurable lines from the Fe group in the optical region. The Fe group species found in the FUV spectra of early B stars are primarily in the second stage of ionization. The best set of lines in the FUSE spectral region are Fe III (UV1), V III 1150 Å, and Cr III 1137 Å. Analysis of the galactic B stars provides a good assessment of the reliability of the atomic parameters that are used for the MC calculations. Twenty-two early B stars in the MC and MB and five in our galaxy were analyzed. In general the Fe group abundances range from solar to slightly below solar in our region of the galaxy. But in the MCs the abundances of V, Cr, and Fe tend to be significantly lower than the mean metal abundances for the galaxy. Maps of the Fe group abundances and their variations in the LMC and SMC, tracers of recent enrichment of the ISM from supernova activity, are shown. Support from NASA grants NAG5-13212, NNX10AD66G, STScI HST-GO-13346.22, and USC’s Women in Science and Engineering (WiSE) program is greatly appreciated.

Fusion of arkosic sand by intrusive andesite

USGS Publications Warehouse

Bailey, Roy A.

1954-01-01

An andesite dike in the Valles Mountains of northern New Mexico has intruded and partly fused arkosic sediments for a distance of 50 feet from its contacts. The dike is semi-circular in form, has a maximum width of about 100 feet, and is about 500 feet long. Small associated arcuate dikes are arranged in spiral fashion around the main dike, suggesting that they were intruded along shear fractures similar to those described by Burbank (1941). The fused rocks surrounding the andesite dike are of three general types: 1) partly fused arkosic sand, 2) fused clay, and 3) hybrid rocks. The fused arkosic sand consists of relict detrital grains of quartz, orthoclose, and plagioclase, imbedded in colorless glass containing microlites of tridymite, cordierite, and magnetite. The relict quartz grains are corroded and embayed by glass; the orthoclase is sanidinized and partly fused; and the plagioclase is inverted to the high temperature form and is partly fused. The fused clay, which was originally a mixture of montmorillonite and hydromica, consists primarily of cordierite but also contains needle-like crystals of sillimanite (?) or mullite (?). The hybrid rocks originated in part by intermixing of fused arkosic sediments and andesitic liquid and in part by diffusion of mafic constituents through the fused sediments. They are rich in cordierite and magnetite and also contain hypersthene, augite, and plagioclase. The composition of pigeonite in the andesite indicates that the temperature of the andesite at the time of intrusion probably did not exceed 1200?C. Samples of arkosic sand were fused in the presence of water in a Morey bomb at 1050?C. Stability relations of certain minerals in the fused sand suggest that fusion may have taken place at a lower temperature, however, and the fluxing action of volatiles from the andesite are thought to have made this possible.

Pixel-based image fusion with false color mapping

NASA Astrophysics Data System (ADS)

Zhao, Wei; Mao, Shiyi

2003-06-01

In this paper, we propose a pixel-based image fusion algorithm that combines the gray-level image fusion method with the false color mapping. This algorithm integrates two gray-level images presenting different sensor modalities or at different frequencies and produces a fused false-color image. The resulting image has higher information content than each of the original images. The objects in the fused color image are easy to be recognized. This algorithm has three steps: first, obtaining the fused gray-level image of two original images; second, giving the generalized high-boost filtering images between fused gray-level image and two source images respectively; third, generating the fused false-color image. We use the hybrid averaging and selection fusion method to obtain the fused gray-level image. The fused gray-level image will provide better details than two original images and reduce noise at the same time. But the fused gray-level image can't contain all detail information in two source images. At the same time, the details in gray-level image cannot be discerned as easy as in a color image. So a color fused image is necessary. In order to create color variation and enhance details in the final fusion image, we produce three generalized high-boost filtering images. These three images are displayed through red, green and blue channel respectively. A fused color image is produced finally. This method is used to fuse two SAR images acquired on the San Francisco area (California, USA). The result shows that fused false-color image enhances the visibility of certain details. The resolution of the final false-color image is the same as the resolution of the input images.

Fiber fuse behavior in kW-level continuous-wave double-clad field laser

NASA Astrophysics Data System (ADS)

Jun-Yi, Sun; Qi-Rong, Xiao; Dan, Li; Xue-Jiao, Wang; Hai-Tao, Zhang; Ma-Li, Gong; Ping, Yan

2016-01-01

In this study, original experimental data for fiber fuse in kW-level continuous-wave (CW) high power double-clad fiber (DCF) laser are reported. The propagating velocity of the fuse is 9.68 m/s in a 3.1-kW Yb-doped DCF laser. Three other cases in Yb-doped DCF are also observed. We think that the ignition of fiber fuse is caused by thermal mechanism, and the formation of bullet-shaped tracks is attributed to the optical discharge and temperature gradient. The inducements of initial fuse and formation of bullet-shaped voids are analyzed. This investigation of fiber fuse helps better understand the fiber fuse behavior, in order to avoid the catastrophic destruction caused by fiber fuse in high power fiber laser. Project supported by the Key Laboratory of Science and Technology on High Energy Laser and China Academy of Engineering Physics (Grant No. 2014HEL02) and the National Natural Science Foundation of China (Grant No. 61307057).

Long-term and stable correction of uremic anemia by intramuscular injection of plasmids containing hypoxia-regulated system of erythropoietin expression

PubMed Central

Wang, Yarong; Du, Dewei; Li, Zhanting; Wei, Junxia; Yang, Angang

2012-01-01

Relative deficiency in production of glycoprotein hormone erythropoietin (Epo) is a major cause of renal anemia. This study planned to investigate whether the hypoxia-regulated system of Epo expression, constructed by fusing Epo gene to the chimeric phosphoglycerate kinase (PGK) hypoxia response elements (HRE) in combination with cytomegalovirus immediate-early (CMV IE) basal gene promoter and delivered by plasmid intramuscular injection, might provide a long-term physiologically regulated Epo secretion expression to correct the anemia in adenine-induced uremic rats. Plasmid vectors (pHRE-Epo) were synthesized by fusing human Epo cDNA to the HRE/CMV promoter. Hypoxia-inducible activity of this promoter was evaluated first in vitro and then in vivo in healthy and uremic rats (n = 30 per group). The vectors (pCMV-Epo) in which Epo expression was directed by a constitutive CMV gene promoter served as control. ANOVA and Student's t-test were used to analyze between-group differences. A high-level expression of Epo was induced by hypoxia in vitro and in vivo. Though both pHRE-Epo and pCMV-Epo corrected anemia, the hematocrit of the pCMV-Epo-treated rats exceeded the normal (P < 0.05), but that of the pHRE-Epo-treated rats didn't. Hypoxia-regulated system of Epo gene expression constructed by fusing Epo to the HRE/CMV promoter and delivered by plasmid intramuscular injection may provide a long-term and stable Epo expression and secretion in vivo to correct the anemia in adenine-induced uremic rats. PMID:22990115

Fused Filament Fabrication of Prosthetic Components for Trans-Humeral Upper Limb Prosthetics

NASA Astrophysics Data System (ADS)

Lathers, Steven M.

Presented below is the design and fabrication of prosthetic components consisting of an attachment, tactile sensing, and actuator systems with Fused Filament Fabrication (FFF) technique. The attachment system is a thermoplastic osseointegrated upper limb prosthesis for average adult trans-humeral amputation with mechanical properties greater than upper limb skeletal bone. The prosthetic designed has: a one-step surgical process, large cavities for bone tissue ingrowth, uses a material that has an elastic modulus less than skeletal bone, and can be fabricated on one system. FFF osseointegration screw is an improvement upon the current two-part osseointegrated prosthetics that are composed of a fixture and abutment. The current prosthetic design requires two invasive surgeries for implantation and are made of titanium, which has an elastic modulus greater than bone. An elastic modulus greater than bone causes stress shielding and overtime can cause loosening of the prosthetic. The tactile sensor is a thermoplastic piezo-resistive sensor for daily activities for a prosthetic's feedback system. The tactile sensor is manufactured from a low elastic modulus composite comprising of a compressible thermoplastic elastomer and conductive carbon. Carbon is in graphite form and added in high filler ratios. The printed sensors were compared to sensors that were fabricated in a gravity mold to highlight the difference in FFF sensors to molded sensors. The 3D printed tactile sensor has a thickness and feel similar to human skin, has a simple fabrication technique, can detect forces needed for daily activities, and can be manufactured in to user specific geometries. Lastly, a biomimicking skeletal muscle actuator for prosthetics was developed. The actuator developed is manufactured with Fuse Filament Fabrication using a shape memory polymer composite that has non-linear contractile and passive forces, contractile forces and strains comparable to mammalian skeletal muscle, reaction time under one second, low operating temperature, and has a low mass, volume, and material costs. The actuator improves upon current prosthetic actuators that provide rigid, linear force with high weight, cost, and noise.

Contemplating the ultimate sacrifice: identity fusion channels pro-group affect, cognition, and moral decision making.

PubMed

Swann, William B; Gómez, Angel; Buhrmester, Michael D; López-Rodríguez, Lucía; Jiménez, Juan; Vázquez, Alexandra

2014-05-01

Although most people acknowledge the moral virtue in sacrificing oneself to save others, few actually endorse self-sacrifice. Seven experiments explored the cognitive and emotional mechanisms that underlie such endorsements. Participants responded to 1 of 2 moral dilemmas in which they could save 5 members of their country only by sacrificing themselves. Over 90% of participants acknowledged that the moral course of action was to sacrifice oneself to save others (Experiment 1), yet only those who were strongly fused with the group preferentially endorsed self-sacrifice (Experiments 2-7). The presence of a concern with saving group members rather than the absence of a concern with self-preservation motivated strongly fused participants to endorse sacrificing themselves for the group (Experiment 3). Analyses of think aloud protocols suggested that saving others was motivated by emotional engagement with the group among strongly fused participants but by utilitarian concerns among weakly fused participants (Experiment 4). Hurrying participants' responses increased self-sacrifice among strongly fused participants but decreased self-sacrifice among weakly fused participants (Experiment 5). Priming the personal self increased endorsement of self-sacrifice among strongly fused participants but further reduced endorsement of self-sacrifice among weakly fused participants (Experiment 6). Strongly fused participants ignored utilitarian considerations, but weakly fused persons endorsed self-sacrifice more when it would save more people (Experiment 7). Apparently, the emotional engagement with the group experienced by strongly fused persons overrides the desire for self-preservation and compels them to translate their moral beliefs into self-sacrificial behavior.

16 CFR 1507.3 - Fuses.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Practices CONSUMER PRODUCT SAFETY COMMISSION FEDERAL HAZARDOUS SUBSTANCES ACT REGULATIONS FIREWORKS DEVICES § 1507.3 Fuses. (a) Fireworks devices that require a fuse shall: (1) Utilize only a fuse that has been... it will support either the weight of the fireworks device plus 8 ounces of dead weight or double the...

Accountability for Information Flow via Explicit Formal Proof

DTIC Science & Technology

2009-10-01

macrobenchmarks. The first (called OpenSSL in the table below), unpacks the OpenSSL source code, compiles it and deletes it. The other (called Fuse in...penalty for PCFS as compared to Fuse/Null is approximately 10% for OpenSSL , and 2.5% for Fuse. The difference arises because the OpenSSL benchmark depends...Macrobenchmarks Benchmark PCFS Fuse/Null Ext3 OpenSSL 126 114 94 Fuse x 5 79 77 70 15 In summary, assuming a low rate of cache misses, the

An Investigation of the Static Force Balance of a Model Railgun

DTIC Science & Technology

2007-06-01

this simple circuit diagram two 950 CCA batteries are passed through a variable resistor (R1) to limit the current applied to the model railgun (R2...of a known value and placed a voltmeter across the resistor . For additional protection in these early trials we inserted an equivalent 1kA fuse...our variable resistor . Current then passed through the resistor into the model gun, through a volt-meter with a known resistance, into a kilo-amp

A hobo transgene that encodes the P-element transposase in Drosophila melanogaster: autoregulation and cytotype control of transposase activity.

PubMed Central

Simmons, Michael J; Haley, Kevin J; Grimes, Craig D; Raymond, John D; Niemi, Jarad B

2002-01-01

Drosophila were genetically transformed with a hobo transgene that contains a terminally truncated but otherwise complete P element fused to the promoter from the Drosophila hsp70 gene. Insertions of this H(hsp/CP) transgene on either of the major autosomes produced the P transposase in both the male and female germlines, but not in the soma. Heat-shock treatments significantly increased transposase activity in the female germline; in the male germline, these treatments had little effect. The transposase activity of two insertions of the H(hsp/CP) transgene was not significantly greater than their separate activities, and one insertion of this transgene reduced the transposase activity of P(ry(+), Delta2-3)99B, a stable P transgene, in the germline as well as in the soma. These observations suggest that, through alternate splicing, the H(hsp/CP) transgene produces a repressor that feeds back negatively to regulate transposase expression or function in both the somatic and germline tissues. The H(hsp/CP) transgenes are able to induce gonadal dysgenesis when the transposase they encode has P-element targets to attack. However, this ability and the ability to induce P-element excisions are repressed by the P cytotype, a chromosomal/cytoplasmic state that regulates P elements in the germline. PMID:12019234

[Evaluation of bond strength between low fusing porcelain with goldplated cobalt-chromium alloys].

PubMed

Guo, Jing; Zhu, Jia; Zhu, Hong-shui

2014-02-01

To evaluate the bond strength of Vita OMEGA 900 low fusing porcelain fused with the goldplated Wirobond cobalt-chrome metalt ceramic alloy. Low fusing porcelain was fused with the cobalt-chromium alloy strips(group A) and the goldplated cobalt-chromium alloy strips(group B) respectively according to ISO9693 (A:8,B:10). 8 specimens of each group were submitted to three point bending test. Two more test pieces fused with gold plated cobalt-chromium alloys were made (group B'). One test piece of both group B and group B' were observed under scanning electron microscope (SEM) randomly. The data was analyzed with SPSS 16.0 software package. The bond strength (MPa) of group A and group B was 29.92±4.28 and 28.20±5.21, respectively (P>0.05), both higher than 25 MPa required by ISO9693. SEM showed that Vita OMEGA 900 low fusing porcelain and the goldplated Wirobond cobalt-chrome metalt ceramic alloy combined together closely without cracks. Much gold was fused to the cobalt-chrome alloy surface of breaking porcelain specimen after testing. Vita OMEGA 900 low fusing porcelain can match with the goldplated Wirobond cobalt-chrome metalt ceramic alloy. Supported by Foundation of Education Department of Jiangxi Province (GJJ10367).

Multispectral image fusion for detecting land mines

DOE Office of Scientific and Technical Information (OSTI.GOV)

Clark, G.A.; Sengupta, S.K.; Aimonetti, W.D.

1995-04-01

This report details a system which fuses information contained in registered images from multiple sensors to reduce the effects of clutter and improve the ability to detect surface and buried land mines. The sensor suite currently consists of a camera that acquires images in six bands (400nm, 500nm, 600nm, 700nm, 800nm and 900nm). Past research has shown that it is extremely difficult to distinguish land mines from background clutter in images obtained from a single sensor. It is hypothesized, however, that information fused from a suite of various sensors is likely to provide better detection reliability, because the suite ofmore » sensors detects a variety of physical properties that are more separable in feature space. The materials surrounding the mines can include natural materials (soil, rocks, foliage, water, etc.) and some artifacts.« less

Focusing experiments in plasma coaxial railguns

NASA Astrophysics Data System (ADS)

Driga, M. D.; Cook, R. W.; Thelen, R. F.

1986-11-01

Results are reported from experiments on focusing of plasma fired from a coaxial electromagnetic gun (CEMG). The plasma used, obtained by exploding a metallic fuse at the gun breech, comprised metal vapor, metallic liquid droplets and small chunks of solid metal. An azimuthal current, and thereby an axial field, was introduced at the breech of the CEMG by a solenoid. Previous studies indicated that the field would cause vaporized metal to form into a self-stabilizing toroidal plasma. Test shots instrumented with Languir probes and pick-up coils did not reveal the presence of toroidal plasma rings. However, post-mortem of the 30 cm rail showed that only one-third of the 3 mg Al fuse metal remained in the bore. Further, a toroidal hole was punched in a diagnostic screen at the bore exit after one shot.

Characterization of Rare Earth Element Minerals in Coal Utilization Byproducts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Montross, Scott N.; Verba, Circe A.; Collins, Keith

The United States currently produces over 100 million tons of coal utilization byproducts (CUB) per year in the form of fly ash, bottom ash, slag, and flue gas (American Coal Ash Association (ACCA), 2015). But this “waste material” also contains potentially useful levels of rare earth elements (REE). Rare earth elements are crucial for many existing and emerging technologies, but the U.S. lacks a domestic, sustainable REE source. Our project explored the possibility of developing a supply of REEs for U.S. technologies by extracting REEs from CUBs. This work offers the potential to reduce our dependence on other countries formore » supply of these critical elements (NETL, REE 2016 Project Portfolio). Geologic and diagenetic history, industrial preparation methods, and the specific combustion process all play major roles in the composition of CUB. During combustion, inorganic mineral phases of coal particles are fluidized at temperatures higher than 1400oC, so inorganic mineral materials are oxidized, fused, disintegrated, or agglomerated into larger spherical and amorphous (non-crystalline) particles. The original mineralogy of the coal-containing rock and heating/cooling of the material significantly affects the composition and morphology of the particles in the combustion byproduct (Kutchko and Kim, 2006). Thus, different types of coal/refuse/ash must be characterized to better understand mineral evolution during the combustion process. Our research focused on developing a working model to address how REE minerals behave during the combustion process: this research should help determine the most effective engineering methods for extracting REEs from CUBs. We used multimodal imaging and image processing techniques to characterize six rock and ash samples from different coal power plants with respect to morphology, grain size, presence of mineral phases, and elemental composition. The results of these characterization activities provided thresholds for realizing the occurrence of REE mineral phases in CUB and allowed us to calculate structural and volumetric estimates of REE. Collectively, the rock and coal ash samples contained minerals such as quartz, kaolinite, muscovite/illite, iron oxide (as hematite or magnetite), mullite, and clinochlore. Trace minerals included pyrite, zircon, siderite, rutile, diopside, foresterite, gypsum, and barite. We identified REE phosphate minerals monazite (Ce,La,Nd,Th)(PO 4,SiO 4), xenotime (YPO 4,SiO 4), and apatite (Ca 5(PO 4) 3(F,Cl,OH) via SEM and electron microprobe analysis: these materials generally occurred as 1-10 μm-long crystals in the rock and ash samples. As has been shown in other studies, amorphous material-aluminosilicate glass or iron oxyhydroxide-are the major components of coal fly and bottom ash. Trace amounts of amorphous calcium oxide and mixed element (e.g., Al-Si-Ca-Fe) slag are also present. Quartz, mullite, hematite, and magnetite are the crystalline phases present. We found that REEs are present as monomineralic grains dispersed within the ash, as well as fused to or encapsulated by amorphous aluminosilicate glass particles. Monazite and xenotime have relatively high melting points (>1800 °C) compared to typical combustion temperatures; our observations indicate that the REE-phosphates, which presumably contribute a large percentage of REE to the bulk ash REE pool, as measured by mass spectroscopy, are largely unaltered by the combustion. Our study shows that conventional coal combustion processes sequester REE minerals into aluminosilicate glass phases, which presents a new engineering challenge for extracting REE from coal ash. The characterization work summarized in this report provides a semi-quantitative assessments of REE in coal-containing rock and CUB. The data we obtained from 2- and 3-D imaging, elemental mapping, volumetric estimates, and advanced high-resolution pixel classification successfully identified the different mineral phases present in CUB. Further, our characterization results can guide techniques for extracting REEs from CUB, or other geologic and engineered materials. Whilst, interpretations will inform future REE separation and extraction techniques and technologies practical for commercial utilization of combustion byproducts generated by power plants.« less

THERMAL RELAY DEVICE

DOEpatents

Murdoch, R.O.; Record, F.A.

1963-01-29

This invention relates to a fast-acting spring-loaded electrical switch which can break a 1500-volt circuit in one millisecond without arcing. In particular, a springloaded shorting bar is held in tension by a fusible wire. Passage of an electrical current pulse through the fusible wire breaks the fuse thereby releasing the shorting bar to open one and close another electrical circuit. (AEC)

Fusing Communication and Writing Skills in the 21st Century's IT/IS Curricula

ERIC Educational Resources Information Center

Liu, Michelle; Murphy, Diane

2012-01-01

Written and oral communication has been listed as the top explicitly requested skill by employers for a long time. Despite pressure from industry, the gap still exists between the expectations and average written and oral communication skills of current information technology/information systems graduates. This paper addresses the above issues and…

Fundamental Use of Surgical Energy (FUSE) certification: validation and predictors of success.

PubMed

Robinson, Thomas N; Olasky, Jaisa; Young, Patricia; Feldman, Liane S; Fuchshuber, Pascal R; Jones, Stephanie B; Madani, Amin; Brunt, Michael; Mikami, Dean; Jackson, Gretchen P; Mischna, Jessica; Schwaitzberg, Steven; Jones, Daniel B

2016-03-01

The Fundamental Use of Surgical Energy (FUSE) program includes a Web-based didactic curriculum and a high-stakes multiple-choice question examination with the goal to provide certification of knowledge on the safe use of surgical energy-based devices. The purpose of this study was (1) to set a passing score through a psychometrically sound process and (2) to determine what pretest factors predicted passing the FUSE examination. Beta-testing of multiple-choice questions on 62 topics of importance to the safe use of surgical energy-based devices was performed. Eligible test takers were physicians with a minimum of 1 year of surgical training who were recruited by FUSE task force members. A pretest survey collected baseline information. A total of 227 individuals completed the FUSE beta-test, and 208 completed the pretest survey. The passing/cut score for the first test form of the FUSE multiple-choice examination was determined using the modified Angoff methodology and for the second test form was determined using a linear equating methodology. The overall passing rate across the two examination forms was 81.5%. Self-reported time studying the FUSE Web-based curriculum for a minimum of >2 h was associated with a passing examination score (p < 0.001). Performance was not different based on increased years of surgical practice (p = 0.363), self-reported expertise on one or more types of energy-based devices (p = 0.683), participation in the FUSE postgraduate course (p = 0.426), or having reviewed the FUSE manual (p = 0.428). Logistic regression found that studying the FUSE didactics for >2 h predicted a passing score (OR 3.61; 95% CI 1.44-9.05; p = 0.006) independent of the other baseline characteristics recorded. The development of the FUSE examination, including the passing score, followed a psychometrically sound process. Self-reported time studying the FUSE curriculum predicted a passing score independent of other pretest characteristics such as years in practice and self-reported expertise.

Cryogenic System for Interferometric Measurement of Dimensional Changes at 40 K: Design and Performance

NASA Technical Reports Server (NTRS)

Blake, Peter; Miller, Franklin; Zukowski, Tim; Canavan, Edgar R.; Crane, Allen; Madison, Tim; Miller, David

2007-01-01

This report describes the facility, experimental methods, characterizations, and uncertainty analysis of the Cryo Distortion Measurement Facility (CDMF) at the Goddard Space Flight Center (GSFC). This facility is designed to measure thermal distortions of structural elements as the temperature is lowered from 320K to below 40 K over multiple cycles, and is capable of unattended running and data logging. The first measurement is to be the change in length and any bending of composite tubes with Invar end-fittings. The CDMF includes a chamber that is efficiently cooled with two cryo-coolers (one single-stage and one two-stage) rather than with liquid cryogens. Five optical ports incorporate sapphire radiation shields - transparent to the interferometer - on each of two shrouds and a fused silica vacuum-port window. The change in length of composite tubes is monitored continuously with displacement-measuring interferometers; and the rotations, bending, and twisting are measured intermittently with theodolites and a surface-figure interferometer. Nickel-coated invar mirrors and attachment mechanisms were developed and qualified by test in the CDMF. The uncertainty in measurement of length change of 0.4 m tubes is currently estimated at 0.9 micrometers.

Development of a Standard Platinum Resistance Thermometer for Use up to the Copper Point

NASA Astrophysics Data System (ADS)

Tavener, J. P.

2015-08-01

The international temperature scale of 1990 defines temperatures in the range from 13.8 K to 1234.93 K () using a standard platinum resistance thermometer (SPRT) as an interpolating instrument. For temperatures above , the current designs of an SPRT require extreme care to avoid contamination, especially by metallic impurities, which can cause rapid and irreversible drift. This study investigates the performance of a new design of a high-temperature SPRT with the aim of improving the stability of the SPRTs and extending their temperature range. The prototype SPRTs have an alumina sheath, a sapphire support for the sensing element, which are aspirated with dry air and operated with a dc bias voltage to suppress the diffusion of metal-ion contaminants. Three prototype thermometers were exposed to temperatures near or above the copper freezing point, , for total exposure times in excess of 500 h and exhibited drifts in the triple-point resistance of less than 10 mK. The new design eliminates some of the problems associated with fused-silica sheaths and sensor-support structures and is a viable option for a high-accuracy thermometer for temperatures approaching.

Commissioning a Rotating Target Wheel Assembly for Heavy Element Studies

NASA Astrophysics Data System (ADS)

Fields, L. D.; Bennett, M. E.; Mayorov, D. A.; Folden, C. M.

2013-10-01

The heaviest elements are produced artificially by fusing nuclei of light elements within an accelerator to form heavier nuclei. The most direct method to increase the production rate of nuclei is to increase the beam intensity, necessitating the use of a rotating target to minimize damage to the target by deposited heat. Such a target wheel was constructed for heavy element research at Texas A&M University, Cyclotron Institute, consisting of a wheel with three banana-shaped target cutouts. The target is designed to rotate at 1700 rpm, and a fiber optic cable provides a signal to trigger beam pulsing in order to avoid irradiating the spokes between target segments. Following minor mechanical modifications and construction of a dedicated electrical panel, the rotating target assembly was commissioned for a beam experiment. A 15 MeV/u beam of 20Ne was delivered from the K500 cyclotron and detected by a ruggedized silicon detector. The beam pulsing response time was characterized as a function of the rational frequency of the target wheel. Preliminary analysis suggests that the K500 is capable of pulsing at rates of up to 250 Hz, which is sufficient for planned future experiments. Funded by DOE and NSF-REU Program.

The research progress of large-aperture fused silica for high power laser

NASA Astrophysics Data System (ADS)

Shao, Zhufeng; Wang, Yufen; Xiang, Zaikui; Rao, Chuandong

2016-03-01

Because of its excellent optical performance, the fused silica is widely used in laser industry. In addition, the fused silica can withstand high power laser, due to its pure component, and the performance is most outstanding within all types of glasses. So fused silica can be used for optical lens in high power laser field. From the manufacturing process stand point, the fused silica can be categorized to four types: type Ⅰ, type Ⅱ, type Ⅲ, and type Ⅳ. The fused silica of type Ⅰand type Ⅱ is made through melting silica sand in graphite furnace or oxyhydrogen flame. There are many defects in these types of fused silica, for example, the air bubbles, inclusions and metallic impurity. The other two types are made by synthetic reaction of SiCl4 with water in oxyhydrogen or plasma flame. Both type Ⅲ and Ⅳ have excellent performance in transmittance and internal quality. However, type Ⅳof fused silica has disadvantage in small aperture and overall high manufacturing cost. Take the transmittance and internal quality into consideration, the type Ⅲ fused silica is the most suitable for large-aperture lens, and can withstand high power laser. The systemic studies of manufacturing process were done to improve the performance of type Ⅲ fused silica in various areas, for instance, the optical homogeneity, the stress birefringence, the absorption coefficient and the damage threshold. There are four steps in manufacturing process of type Ⅲ fused silica, ingot production, reshaping, annealing and cold-working. The critical factors of ingot production, like the flame of burner and the structure of furnace, were deeply studied in this paper to improve the performance of fused silica. On the basis of the above research, the performance and quality of the fused silica measured up to advanced world levels. For instance, the result of optical homogeneity can be controlled to 2-5 ppm, the stress birefringence is better than 4 nm/cm, the absorption coefficient is about 5.971ppm cm-1 (1ω), the damage threshold is greater than 80, 25 and 23 J/cm2 with the wavelength at 1064, 532 and 351nm respectively, the bandwidth used for measuring is 3ns.The fused silica has already been used in the area of high power laser facilities, aerospace industry, primary lens of interferometer based on its excellent performance.

Collinear integration affects visual search at V1.

PubMed

Chow, Hiu Mei; Jingling, Li; Tseng, Chia-huei

2013-08-29

Perceptual grouping plays an indispensable role in figure-ground segregation and attention distribution. For example, a column pops out if it contains element bars orthogonal to uniformly oriented element bars. Jingling and Tseng (2013) have reported that contextual grouping in a column matters to visual search behavior: When a column is grouped into a collinear (snakelike) structure, a target positioned on it became harder to detect than on other noncollinear (ladderlike) columns. How and where perceptual grouping interferes with selective attention is still largely unknown. This article contributes to this little-studied area by asking whether collinear contour integration interacts with visual search before or after binocular fusion. We first identified that the previously mentioned search impairment occurs with a distractor of five or nine elements but not one element in a 9 × 9 search display. To pinpoint the site of this effect, we presented the search display with a short collinear bar (one element) to one eye and the extending collinear bars to the other eye, such that when properly fused, the combined binocular collinear length (nine elements) exceeded the critical length. No collinear search impairment was observed, implying that collinear information before binocular fusion shaped participants' search behavior, although contour extension from the other eye after binocular fusion enhanced the effect of collinearity on attention. Our results suggest that attention interacts with perceptual grouping as early as V1.

An internal regulatory element controls troponin I gene expression

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yutzey, K.E.; Kline, R.L.; Konieczmy, S.F.

1989-04-01

During skeletal myogenesis, approximately 20 contractile proteins and related gene products temporally accumulate as the cells fuse to form multinucleated muscle fibers. In most instances, the contractile protein genes are regulated transcriptionally, which suggests that a common molecular mechanism may coordinate the expression of this diverse and evolutionarily unrelated gene set. Recent studies have examined the muscle-specific cis-acting elements associated with numerous contractile protein genes. All of the identified regulatory elements are positioned in the 5'-flanking regions, usually within 1,500 base pairs of the transcription start site. Surprisingly, a DNA consensus sequence that is common to each contractile protein genemore » has not been identified. In contrast to the results of these earlier studies, the authors have found that the 5'-flanking region of the quail troponin I (TnI) gene is not sufficient to permit the normal myofiber transcriptional activation of the gene. Instead, the TnI gene utilizes a unique internal regulatory element that is responsible for the correct myofiber-specific expression pattern associated with the TnI gene. This is the first example in which a contractile protein gene has been shown to rely primarily on an internal regulatory element to elicit transcriptional activation during myogenesis. The diversity of regulatory elements associated with the contractile protein genes suggests that the temporal expression of the genes may involve individual cis-trans regulatory components specific for each gene.« less

An internal regulatory element controls troponin I gene expression.

PubMed Central

Yutzey, K E; Kline, R L; Konieczny, S F

1989-01-01

During skeletal myogenesis, approximately 20 contractile proteins and related gene products temporally accumulate as the cells fuse to form multinucleated muscle fibers. In most instances, the contractile protein genes are regulated transcriptionally, which suggests that a common molecular mechanism may coordinate the expression of this diverse and evolutionarily unrelated gene set. Recent studies have examined the muscle-specific cis-acting elements associated with numerous contractile protein genes. All of the identified regulatory elements are positioned in the 5'-flanking regions, usually within 1,500 base pairs of the transcription start site. Surprisingly, a DNA consensus sequence that is common to each contractile protein gene has not been identified. In contrast to the results of these earlier studies, we have found that the 5'-flanking region of the quail troponin I (TnI) gene is not sufficient to permit the normal myofiber transcriptional activation of the gene. Instead, the TnI gene utilizes a unique internal regulatory element that is responsible for the correct myofiber-specific expression pattern associated with the TnI gene. This is the first example in which a contractile protein gene has been shown to rely primarily on an internal regulatory element to elicit transcriptional activation during myogenesis. The diversity of regulatory elements associated with the contractile protein genes suggests that the temporal expression of the genes may involve individual cis-trans regulatory components specific for each gene. Images PMID:2725509

Development of a high temperature capacitive pressure transducer

NASA Technical Reports Server (NTRS)

Egger, R. L.

1977-01-01

High temperature pressure transducers capable of continuous operation while exposed to 650 C were developed and evaluated over a full-scale differential pressure range of + or - 69 kPa. The design of the pressure transducers was based on the use of a diaphragm to respond to pressure, variable capacitive elements arranged to operate as a differential capacitor to measure diaphragm response and on the use of fused silica for the diaphragm and its supporting assembly. The uncertainty associated with measuring + or - 69 kPa pressures between 20C and 650C was less than + or - 6%.

31 CFR 100.12 - Exchange of fused and mixed coins.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false Exchange of fused and mixed coins... of fused and mixed coins. (a) Definitions. (1) Fused coins are U.S. coins which are melted to the....S. coins. (2) Mixed coins are U.S. coins of several alloy categories which are presented together...

31 CFR 100.12 - Exchange of fused and mixed coins.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Exchange of fused and mixed coins... of fused and mixed coins. (a) Definitions. (1) Fused coins are U.S. coins which are melted to the....S. coins. (2) Mixed coins are U.S. coins of several alloy categories which are presented together...

31 CFR 100.12 - Exchange of fused and mixed coins.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false Exchange of fused and mixed coins... of fused and mixed coins. (a) Definitions. (1) Fused coins are U.S. coins which are melted to the....S. coins. (2) Mixed coins are U.S. coins of several alloy categories which are presented together...

31 CFR 100.12 - Exchange of fused and mixed coins.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false Exchange of fused and mixed coins... of fused and mixed coins. (a) Definitions. (1) Fused coins are U.S. coins which are melted to the....S. coins. (2) Mixed coins are U.S. coins of several alloy categories which are presented together...

Integrated fuses for OLED lighting device

DOEpatents

Pschenitzka, Florian [San Jose, CA

2007-07-10

An embodiment of the present invention pertains to an electroluminescent lighting device for area illumination. The lighting device is fault tolerant due, in part, to the patterning of one or both of the electrodes into strips, and each of one or more of these strips has a fuse formed on it. The fuses are integrated on the substrate. By using the integrated fuses, the number of external contacts that are used is minimized. The fuse material is deposited using one of the deposition techniques that is used to deposit the thin layers of the electroluminescent lighting device.

Sensor feature fusion for detecting buried objects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Clark, G.A.; Sengupta, S.K.; Sherwood, R.J.

1993-04-01

Given multiple registered images of the earth`s surface from dual-band sensors, our system fuses information from the sensors to reduce the effects of clutter and improve the ability to detect buried or surface target sites. The sensor suite currently includes two sensors (5 micron and 10 micron wavelengths) and one ground penetrating radar (GPR) of the wide-band pulsed synthetic aperture type. We use a supervised teaming pattern recognition approach to detect metal and plastic land mines buried in soil. The overall process consists of four main parts: Preprocessing, feature extraction, feature selection, and classification. These parts are used in amore » two step process to classify a subimage. Thee first step, referred to as feature selection, determines the features of sub-images which result in the greatest separability among the classes. The second step, image labeling, uses the selected features and the decisions from a pattern classifier to label the regions in the image which are likely to correspond to buried mines. We extract features from the images, and use feature selection algorithms to select only the most important features according to their contribution to correct detections. This allows us to save computational complexity and determine which of the sensors add value to the detection system. The most important features from the various sensors are fused using supervised teaming pattern classifiers (including neural networks). We present results of experiments to detect buried land mines from real data, and evaluate the usefulness of fusing feature information from multiple sensor types, including dual-band infrared and ground penetrating radar. The novelty of the work lies mostly in the combination of the algorithms and their application to the very important and currently unsolved operational problem of detecting buried land mines from an airborne standoff platform.« less

Two cis elements collaborate to spatially repress transcription from a sea urchin promoter

NASA Technical Reports Server (NTRS)

Frudakis, T. N.; Wilt, F.

1995-01-01

The expression pattern of many territory-specific genes in metazoan embryos is maintained by an active process of negative spatial regulation. However, the mechanism of this strategy of gene regulation is not well understood in any system. Here we show that reporter constructs containing regulatory sequence for the SM30-alpha gene of Stronglyocentrotus purpuratus are expressed in a pattern congruent with that of the endogenous SM30 gene(s), largely as a result of active transcriptional repression in cell lineages in which the gene is not normally expressed. Chloramphenicol acetyl transferase assays of deletion constructs from the 2600-bp upstream region showed that repressive elements were present in the region from -1628 to -300. In situ hybridization analysis showed that the spatial fidelity of expression was severely compromised when the region from -1628 to -300 was deleted. Two highly repetitive sequence motifs, (G/A/C)CCCCT and (T/C)(T/A/C)CTTTT(T/A/C), are present in the -1628 to -300 region. Representatives of these elements were analyzed by gel mobility shift experiments and were found to interact specifically with protein in crude nuclear extracts. When oligonucleotides containing either sequence element were co-injected with a correctly regulated reporter as potential competitors, the reporter was expressed in inappropriate cells. When composite oligonucleotides, containing both sequence elements, were fused to a misregulated reporter, the expression of the reporter in inappropriate cells was suppressed. Comparison of composite oligonucleotides with oligonucleotides containing single constituent elements show that both sequence elements are required for effective spatial regulation. Thus, both individual elements are required, but only a composite element containing both elements is sufficient to function as a tissue-specific repressive element.

Combined quantum chemical density functional theory and spectroscopic Raman and UV-vis-NIR study of oligothienoacenes with five and seven rings.

PubMed

Osuna, Reyes Malavé; Zhang, Xinnan; Matzger, Adam Jay; Hernandez, Víctor; López Navarrete, Juan Teodomiro

2006-04-20

In this article, we report the characterization of novel oligothienoacenes with five and seven fused thiophene rings, materials with potential applications in organic electronics. In contrast to usual alpha-linked oligothiophenes, these fused oligothiophenes have a larger band gap than most semiconductors currently used in the fabrication of organic field-effect transistors (OFETs) and therefore they are expected to be more stable in air. The synthesis of these fused-ring oligomers was motivated by the notion that a more rigid and planar structure should reduce defects (such as torsion about single bonds between alpha-linked units or S-syn defects) and thus improve conjugation for better charge-carrier mobility. The conjugational properties of these two molecular materials have been investigated by means of FT-Raman spectroscopy, revealing that conjugation still increases in passing from the five-ring oligomer to that with seven-rings. DFT and TDDFT quantum chemical calculations have been performed, at the B3LYP/6-31G level, to assess information regarding the minimum-energy molecular structure, topologies, and absolute energies of the frontier molecular orbitals (MOs.) around the gap, vibrational normal modes related to the main Raman features, and vertical one-electron excitations giving rise to the main optical absorptions.

Synthesis and Evaluation of Cytotoxic Activity of Some Pyrroles and Fused Pyrroles.

PubMed

Fatahala, Samar S; Mohamed, Mosaad S; Youns, Mahmoud; Abd-El Hameed, Rania H

2017-01-01

Pyrrole derivatives represent a very interesting class as biologically active compounds. The objective of our study was to investigate the cytotoxic and apoptotic effects and antioxidant activity of the newly synthesized pyrrole derivatives. A series of novel pyrroles and fused pyrroles (tetrahydroindoles, pyrrolopyrimidines, pyrrolopyridines and pyrrolotriazines) were synthesized and characterized using IR, 1H NMR, 13C NMR, MS and elemental analysis techniques. The antiproliferative activity of our synthesized compounds and their modulatory effect apoptotic pathway were investigated. The effect on cellular proliferation and viability was monitored by resazurin assay. Apoptotic effect was evaluated by caspase glo 3/7 assay. Synthesized compounds are then tested for their anticancer activities against three different cell lines representing three different tumor types, namely; the HepG-2 (Human hepatocellular liver carcinoma cell line), the human MCF-7 cell line (breast cancer) and the pancreatic resistant Panc-1 cells. Compounds Ia-e, IIe, and IXc, d showed a promising anti-cancer activity on all tested cell lines. Antioxidant and wound healing invasion assays were examined for promising anticancer candidate compounds. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

High-performance packaging for monolithic microwave and millimeter-wave integrated circuits

NASA Technical Reports Server (NTRS)

Shalkhauser, K. A.; Li, K.; Shih, Y. C.

1992-01-01

Packaging schemes were developed that provide low-loss, hermetic enclosure for advanced monolithic microwave and millimeter-wave integrated circuits (MMICs). The package designs are based on a fused quartz substrate material that offers improved radio frequency (RF) performance through 44 gigahertz (GHz). The small size and weight of the packages make them appropriate for a variety of applications, including phased array antenna systems. Packages were designed in two forms; one for housing a single MMIC chip, the second in the form of a multi-chip phased array module. The single chip array module was developed in three separate sizes, for chips of different geometry and frequency requirements. The phased array module was developed to address packaging directly for antenna applications, and includes transmission line and interconnect structures to support multi-element operation. All packages are fabricated using fused quartz substrate materials. As part of the packaging effort, a test fixture was developed to interface the single chip packages to conventional laboratory instrumentation for characterization of the packaged devices. The package and test fixture designs were both developed in a generic sense, optimizing performance for a wide range of possible applications and devices.

Rearrangement of Immunoglobulin Genes in Shark Germ Cells

PubMed Central

Lee, Susan S.; Fitch, David; Flajnik, Martin F.; Hsu, Ellen

2000-01-01

The variable (V), (diversity [D]), and joining (J) region recombinases (recombination activating genes [RAGs]) can perform like transposases and are thought to have initiated development of the adaptive immune system in early vertebrates by splitting archaic V genes with transposable elements. In cartilaginous fishes, the immunoglobulin (Ig) light chain genes are organized as multiple VJ-constant (C) clusters; some loci are capable of rearrangement while others contain fused VJ. The latter may be key to understanding the evolutionary role of RAG. Are they relics of the archaic genes, or are they results of rearrangement in germ cells? Our data suggest that some fused VJ genes are not only recently rearranged, but also resulted from RAG-like activity involving hairpin intermediates. Expression studies show that these, like some other germline-joined Ig sequences, are expressed at significant levels only early in ontogeny. We suggest that a rejoined Ig gene may not merely be a sequence restricting antibody diversity, but is potentially a novel receptor no longer tied to somatic RAG expression and rearrangement. From the combined data, we arrived at the unexpected conclusion that, in some vertebrates, RAG is still an active force in changing the genome. PMID:10811858

Graphite for the nuclear industry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burchell, T.D.; Fuller, E.L.; Romanoski, G.R.

Graphite finds applications in both fission and fusion reactors. Fission reactors harness the energy liberated when heavy elements, such as uranium or plutonium, fragment or fission''. Reactors of this type have existed for nearly 50 years. The first nuclear fission reactor, Chicago Pile No. 1, was constructed of graphite under a football stand at Stagg Field, University of Chicago. Fusion energy devices will produce power by utilizing the energy produced when isotopes of the element hydrogen are fused together to form helium, the same reaction that powers our sun. The role of graphite is very different in these two reactormore » systems. Here we summarize the function of the graphite in fission and fusion reactors, detailing the reasons for their selection and discussing some of the challenges associated with their application in nuclear fission and fusion reactors. 10 refs., 15 figs., 1 tab.« less

Genetic transformation of the plant pathogens Phytophthora capsici and Phytophthora parasitica.

PubMed Central

Bailey, A M; Mena, G L; Herrera-Estrella, L

1991-01-01

Phytophthora capsici and P.parasitica were transformed to hygromycin B resistance using plasmids pCM54 and pHL1, which contain the bacterial hygromycin B phosphotransferase gene (hph) fused to promoter elements of the Ustilago maydis heat shock hsp70 gene. Enzymes Driselase and Novozyme 234 were used to generate protoplasts which were then transformed following exposure to plasmid DNA and polyethylene glycol 6000. Transformation frequencies of over 500 transformants per micrograms of DNA per 1 x 10(6) protoplasts were obtained. Plasmid pCM54 appears to be transmitted in Phytophthora spp. as an extra-chromosomal element through replication, as shown by Southern blot hybridization and by the loss of plasmid methylation. In addition, transformed strains retained their capacity of infecting Serrano pepper seedlings and Mc. Intosh apple fruits, the host plants for P.capsici and P.parasitica, respectively. Images PMID:1651483

A rapid and practical strategy for the determination of platinum, palladium, ruthenium, rhodium, iridium and gold in large amounts of ultrabasic rock by inductively coupled plasma optical emission spectrometry combined with ultrasound extraction

NASA Astrophysics Data System (ADS)

Zhang, Gai; Tian, Min

2015-04-01

This proposed method regulated the determination of platinum, palladium, ruthenium, rhodium, iridium and gold in platinum-group ores by nickel sulfide fire assay—inductively coupled plasma optical emission spectrometry (ICP-OES) combined with ultrasound extraction for the first time. The quantitative limits were 0.013-0.023μg/g. The samples were fused to separate the platinum-group elements from matrix. The nickel sulfide button was then dissolved with hydrochloric acid and the insoluble platinum-group sulfide residue was dissolved with aqua regia by ultrasound bath and finally determined by ICP-OES. The proposed method has been applied into the determination of platinum-group element and gold in large amounts of ultrabasic rocks from the Great Dyke of Zimbabwe.

Non-destructive evaluation of UV pulse laser-induced damage performance of fused silica optics.

PubMed

Huang, Jin; Wang, Fengrui; Liu, Hongjie; Geng, Feng; Jiang, Xiaodong; Sun, Laixi; Ye, Xin; Li, Qingzhi; Wu, Weidong; Zheng, Wanguo; Sun, Dunlu

2017-11-24

The surface laser damage performance of fused silica optics is related to the distribution of surface defects. In this study, we used chemical etching assisted by ultrasound and magnetorheological finishing to modify defect distribution in a fused silica surface, resulting in fused silica samples with different laser damage performance. Non-destructive test methods such as UV laser-induced fluorescence imaging and photo-thermal deflection were used to characterize the surface defects that contribute to the absorption of UV laser radiation. Our results indicate that the two methods can quantitatively distinguish differences in the distribution of absorptive defects in fused silica samples subjected to different post-processing steps. The percentage of fluorescence defects and the weak absorption coefficient were strongly related to the damage threshold and damage density of fused silica optics, as confirmed by the correlation curves built from statistical analysis of experimental data. The results show that non-destructive evaluation methods such as laser-induced fluorescence and photo-thermal absorption can be effectively applied to estimate the damage performance of fused silica optics at 351 nm pulse laser radiation. This indirect evaluation method is effective for laser damage performance assessment of fused silica optics prior to utilization.

[Effects of laser welding on bond of porcelain fused cast pure titanium].

PubMed

Zhu, Juan-fang; He, Hui-ming; Gao, Bo; Wang, Zhong-yi

2006-04-01

To investigate the influence of the laser welding on bond of porcelain fused to cast pure titanium. Twenty cast titanium plates were divided into two groups: laser welded group and control group. The low-fusing porcelain was fused to the laser welded cast pure titanium plates at fusion zone. The bond strength of the porcelain to laser welded cast pure titanium was measured by the three-point bending test. The interface of titanium and porcelain was investigated by scanning electron microscopy (SEM) and energy depressive X-ray detector (EDX). The non-welded titanium plates were used as comparison. No significant difference of the bond strength was found between laser-welded samples [(46.85 +/- 0.76) MPa] and the controls [(41.71 +/- 0.55) MPa] (P > 0.05). The SEM displayed the interface presented similar irregularities with a predominance. The titanium diffused to low-fusing porcelain, while silicon and aluminum diffused to titanium basement. Laser welding does not affect low-fusing porcelain fused to pure titanium.

Pulse generator with intermediate inductive storage as a lightning simulator

NASA Astrophysics Data System (ADS)

Kovalchuk, B. M.; Kharlov, A. V.; Zherlytsyn, A. A.; Kumpyak, E. V.; Tsoy, N. V.

2016-06-01

Compact transportable generators are required for simulating a lightning current pulse for electrical apparatus testing. A bi-exponential current pulse has to be formed by such a generator (with a current rise time of about two orders of magnitude faster than the damping time). The objective of this study was to develop and investigate a compact pulse generator with intermediate inductive storage and a fuse opening switch as a simulator of lightning discharge. A Marx generator (six stages) with a capacitance of 1 μF and an output voltage of 240 kV was employed as primary storage. In each of the stages, two IK-50/3 (50 kV, 3 μF) capacitors are connected in parallel. The generator inductance is 2 μH. A test bed for the investigations was assembled with this generator. The generator operates without SF6 and without oil in atmospheric air, which is very important in practice. Straight copper wires with adjustable lengths and diameters were used for the electro-explosive opening switch. Tests were made with active-inductive loads (up to 0.1 Ω and up to 6.3 μH). The current rise time is lower than 1200 ns, and the damping time can be varied from 35 to 125 μs, following the definition of standard lightning current pulse in the IEC standard. Moreover, 1D MHD calculations of the fuse explosion were carried out self-consistently with the electric circuit equations, in order to calculate more accurately the load pulse parameters. The calculations agree fairly well with the tests. On the basis of the obtained results, the design of a transportable generator was developed for a lightning simulator with current of 50 kA and a pulse shape corresponding to the IEEE standard.

Proof Of Concept of Integrated Load Measurement in 3D Printed Structures

DOE PAGES

Hinderdael, Michael; Strantza, Maria; De Baere, Dieter; ...

2017-02-09

Currently, research on structural health monitoring systems is focused on direct integration of the system into a component or structure. The latter results in a so-called smart structure. One example of a smart structure is a component with integrated strain sensing for continuous load monitoring. Additive manufacturing, or 3D printing, now also enables such integration of functions inside components. As a proof-of-concept, the Fused Deposition Modeling (FDM) technique was used to integrate a strain sensing element inside polymer (ABS) tensile test samples. The strain sensing element consisted of a closed capillary filled with a fluid and connected to an externallymore » mounted pressure sensor. The volumetric deformation of the integrated capillary resulted in pressure changes in the fluid. The obtained pressure measurements during tensile testing are reported in this paper and compared to state-of-the-art extensometer measurements. The sensitivity of the 3D printed pressure-based strain sensor is primarily a function of the compressibility of the capillary fluid. Air- and watertightness are of critical importance for the proper functioning of the 3D printed pressure-based strain sensor. Therefore, the best after-treatment procedure was selected on basis of a comparative analysis. The obtained pressure measurements are linear with respect to the extensometer readings, and the uncertainty on the strain measurement of a capillary filled with water (incompressible fluid) is ±3.1 µstrain, which is approximately three times less sensitive than conventional strain gauges (±1 µstrain), but 32 times more sensitive than the same sensor based on air (compressible fluid) (±101 µstrain).« less

Proof Of Concept of Integrated Load Measurement in 3D Printed Structures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hinderdael, Michael; Strantza, Maria; De Baere, Dieter

Currently, research on structural health monitoring systems is focused on direct integration of the system into a component or structure. The latter results in a so-called smart structure. One example of a smart structure is a component with integrated strain sensing for continuous load monitoring. Additive manufacturing, or 3D printing, now also enables such integration of functions inside components. As a proof-of-concept, the Fused Deposition Modeling (FDM) technique was used to integrate a strain sensing element inside polymer (ABS) tensile test samples. The strain sensing element consisted of a closed capillary filled with a fluid and connected to an externallymore » mounted pressure sensor. The volumetric deformation of the integrated capillary resulted in pressure changes in the fluid. The obtained pressure measurements during tensile testing are reported in this paper and compared to state-of-the-art extensometer measurements. The sensitivity of the 3D printed pressure-based strain sensor is primarily a function of the compressibility of the capillary fluid. Air- and watertightness are of critical importance for the proper functioning of the 3D printed pressure-based strain sensor. Therefore, the best after-treatment procedure was selected on basis of a comparative analysis. The obtained pressure measurements are linear with respect to the extensometer readings, and the uncertainty on the strain measurement of a capillary filled with water (incompressible fluid) is ±3.1 µstrain, which is approximately three times less sensitive than conventional strain gauges (±1 µstrain), but 32 times more sensitive than the same sensor based on air (compressible fluid) (±101 µstrain).« less

Proof of Concept of Integrated Load Measurement in 3D Printed Structures

PubMed Central

Hinderdael, Michaël; Jardon, Zoé; Lison, Margot; De Baere, Dieter; Devesse, Wim; Strantza, Maria; Guillaume, Patrick

2017-01-01

Currently, research on structural health monitoring systems is focused on direct integration of the system into a component or structure. The latter results in a so-called smart structure. One example of a smart structure is a component with integrated strain sensing for continuous load monitoring. Additive manufacturing, or 3D printing, now also enables such integration of functions inside components. As a proof-of-concept, the Fused Deposition Modeling (FDM) technique was used to integrate a strain sensing element inside polymer (ABS) tensile test samples. The strain sensing element consisted of a closed capillary filled with a fluid and connected to an externally mounted pressure sensor. The volumetric deformation of the integrated capillary resulted in pressure changes in the fluid. The obtained pressure measurements during tensile testing are reported in this paper and compared to state-of-the-art extensometer measurements. The sensitivity of the 3D printed pressure-based strain sensor is primarily a function of the compressibility of the capillary fluid. Air- and watertightness are of critical importance for the proper functioning of the 3D printed pressure-based strain sensor. Therefore, the best after-treatment procedure was selected on basis of a comparative analysis. The obtained pressure measurements are linear with respect to the extensometer readings, and the uncertainty on the strain measurement of a capillary filled with water (incompressible fluid) is ±3.1 µstrain, which is approximately three times less sensitive than conventional strain gauges (±1 µstrain), but 32 times more sensitive than the same sensor based on air (compressible fluid) (±101 µstrain). PMID:28208779

Land mine detection using multispectral image fusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Clark, G.A.; Sengupta, S.K.; Aimonetti, W.D.

1995-03-29

Our system fuses information contained in registered images from multiple sensors to reduce the effects of clutter and improve the ability to detect surface and buried land mines. The sensor suite currently consists of a camera that acquires images in six bands (400nm, 500nm, 600nm, 700nm, 800nm and 900nm). Past research has shown that it is extremely difficult to distinguish land mines from background clutter in images obtained from a single sensor. It is hypothesized, however, that information fused from a suite of various sensors is likely to provide better detection reliability, because the suite of sensors detects a varietymore » of physical properties that are more separable in feature space. The materials surrounding the mines can include natural materials (soil, rocks, foliage, water, etc.) and some artifacts. We use a supervised learning pattern recognition approach to detecting the metal and plastic land mines. The overall process consists of four main parts: Preprocessing, feature extraction, feature selection, and classification. These parts are used in a two step process to classify a subimage. We extract features from the images, and use feature selection algorithms to select only the most important features according to their contribution to correct detections. This allows us to save computational complexity and determine which of the spectral bands add value to the detection system. The most important features from the various sensors are fused using a supervised learning pattern classifier (the probabilistic neural network). We present results of experiments to detect land mines from real data collected from an airborne platform, and evaluate the usefulness of fusing feature information from multiple spectral bands.« less

The apparatus composition and architecture of Cordylodus pander - Concepts of homology in primitive conodonts

USGS Publications Warehouse

Smith, M.P.; Donoghue, P.C.J.; Repetski, J.E.

2005-01-01

A clear distinction may be drawn between the perpendicular architecture of the feeding apparatus of ozarkodinid, prioniodontid and prioniodinid conodonts, in which the P elements are situated at a high angle to the M and S elements, and the parallel architecture of panderodontid and other coniform apparatuses, where two suites of coniform elements lie parallel to each other and oppose across the midline. The quest for homologies between the two architectures has been fraught with difficulty, at least in part because of the paucity of natural assemblages of coniform taxa. A diagenetically fused apparatus of Cordylodns lindstroini elements is here described which is made up of one rounded and two compressed element morphotypes. One of the compressed elements is bowed and asymmetrical and the other is unbowed and more symmetrical. These compressed elements are considered to be homologous with those of panderodontid apparatuses and would have lain at the caudal end of the parallel arrays, with the more symmetrical morphotypes located rostrally to the asymmetrical ones. The bowed and unbowed compressed elements of Cordylodns thus correspond, respectively, to the pt and pf positions of panderodontid apparatuses. In addition, the presence of symmetry transition within the rounded elements of Cordylodns, but not the compressed morphotypes, enables correlation of these with the S and M element locations of ozarkodinid apparatuses. By extension, the compressed elements must be homologues of the P elements. Specifically, the asymmetrical pt morphotype is homologous with the P1 of ozarkodinids and the more symmetrical and rostral pf morphotype is homologous with the P2 position. However, because of uncertainties over the nature of topological transformation of the rostral element array (the "rounded" or "costate" suites), it is not possible to recognize specific homologies between these elements and the M and S elements of ozarkodinids. Morphologic differentiation of P from M and S element suites thus preceded the topological transformation from parallel to perpendicular apparatus architectures.

Multiwavelength Observations of the Hot DB Star PG 0112+104

NASA Astrophysics Data System (ADS)

Dufour, P.; Desharnais, S.; Wesemael, F.; Chayer, P.; Lanz, T.; Bergeron, P.; Fontaine, G.; Beauchamp, A.; Saffer, R. A.; Kruk, J. W.; Limoges, M.-M.

2010-08-01

We present a comprehensive multiwavelength analysis of the hot DB white dwarf PG 0112+104. Our analysis relies on newly acquired FUSE observations, on medium-resolution FOS and GHRS data, on archival high-resolution GHRS observations, on optical spectrophotometry both in the blue and around Hα, as well as on time-resolved photometry. From the optical data, we derive a self-consistent effective temperature of 31,300 ± 500 K, a surface gravity of log g = 7.8 ± 0.1 (M = 0.52 M sun), and a hydrogen abundance of log N(H)/N(He)< -4.0. The FUSE spectra reveal the presence of C II and C III lines that complement the previous detection of C II transitions with the GHRS. The improved carbon abundance in this hot object is log N(C)/N(He) = -6.15 ± 0.23. No photospheric features associated with other heavy elements are detected. We reconsider the role of PG 0112+104 in the definition of the blue edge of the V777 Her instability strip in light of our high-speed photometry and contrast our results with those of previous observations carried out at the McDonald Observatory. Based on observations with the FUSE satellite, which is operated by the Johns Hopkins University under NASA contract NAS 5-32985; with the NASA/ESA Hubble Space Telescope, obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under the NASA contract NAS 5-26555; and with the Kitt Peak National Observatory, National Optical Astronomy Observatories, operated by the Association of Universities for Research in Astronomy, Inc., under cooperative agreement with the National Science Foundation.

Crossing the Boundaries of Employee Engagement and Workplace Diversity and Inclusion: Moving HRD Forward in a Complicated Sociopolitical Climate

ERIC Educational Resources Information Center

Pleasant, Stephanie

2017-01-01

This essay explores the intersection of employee engagement and workplace diversity and inclusion. The current trend of organizations fusing these two concepts has provided motivation to examine the (dis)connection between theory and practice. This essay advances the perspectives of practitioners, as well as a critical framework used to discuss…

Enhanced dielectric standoff and mechanical failure in field-structured composites

NASA Astrophysics Data System (ADS)

Martin, James E.; Tigges, Chris P.; Anderson, Robert A.; Odinek, Judy

1999-09-01

We report dielectric breakdown experiments on electric-field-structured composites of high-dielectric-constant BaTiO3 particles in an epoxy resin. These experiments show a significant increase in the dielectric standoff strength perpendicular to the field structuring direction, relative to control samples consisting of randomly dispersed particles. To understand the relation of this observation to microstructure, we apply a simple resistor-short breakdown model to three-dimensional composite structures generated from a dynamical simulation. In this breakdown model the composite material is assumed to conduct primarily through particle contacts, so the simulated structures are mapped onto a resistor network where the center of mass of each particle is a node that is connected to neighboring nodes by resistors of fixed resistance that irreversibly short to perfect conductors when the current reaches a threshold value. This model gives relative breakdown voltages that are in good agreement with experimental results. Finally, we consider a primitive model of the mechanical strength of a field-structured composite material, which is a current-driven, conductor-insulator fuse model. This model leads to a macroscopic fusing behavior and can be related to mechanical failure of the composite.

Characterization of two distinctly different mineral-related proteins from the teeth of the Camarodont sea urchin Lytechinus variegatus: Specificity of function with relation to mineralization

NASA Astrophysics Data System (ADS)

Veis, A.; Alvares, K.; Dixit, S. N.; Robach, J. S.; Stock, S. R.

2009-06-01

The majority of the mineral phase of the Lytechinus variegatus tooth is comprised of magnesium containing calcite crystal elements, collectively arranged so that they appear as a single crystal under polarized light, as well as under X-ray or electron irradiation. However, the crystal elements are small, and in spite of the common alignment of their crystal axes, are not the same size or shape in different parts of the tooth. The toughness of the tooth structure arises from the fact that it is a composite in which the crystals are coated with surface layers of organic matter that probably act to inhibit crack formation and elongation. In the growth region the organic components represent a greater part of the tooth structure. In the most heavily mineralized adoral region the primary plates fuse with inter-plate pillars. Using Scanning Electron Microscopy; TOF-SIMS mapping of the characteristic amino acids of the mineral related proteins; and isolation and characterization of the mineral-protected protein we report that the late-forming inter-plate pillars had more than a three-fold greater Mg content than the primary plates. Furthermore, the aspartic acid content of the mineralrelated protein was highest in the high Mg pillars whereas the mineral-protected protein of the primary plates was richer in glutamic acid content.These results suggest that the Asp-rich protein(s) is important for formation of the late developing inter-plate pillars that fuse the primary plates and increase the stiffness of the most mature tooth segment. Supported by NIDCR Grant DE R01-01374 to AV.

Spondylectomy and lateral lumbar interbody fusion for thoracolumbar kyphosis in an adult with achondroplasia: A case report.

PubMed

Miyazaki, Masashi; Kanezaki, Shozo; Notani, Naoki; Ishihara, Toshinobu; Tsumura, Hiroshi

2017-12-01

Fixed thoracolumbar kyphosis with spinal stenosis in adult patients with achondroplasia presents a challenging issue. We describe the first case in which spondylectomy and minimally invasive lateral access interbody arthrodesis were used for the treatment of fixed severe thoracolumbar kyphosis and lumbar spinal canal stenosis in an adult with achondroplasia. A 61-year-old man with a history of achondroplastic dwarfism presented with low back pain and radiculopathy and neurogenic claudication. Plain radiographs revealed a high-grade thoracolumbar kyphotic deformity with diffuse degenerative changes in the lumbar spine. The apex was located at L2, the local kyphotic angle from L1 to L3 was 105°, and the anterior area was fused from the L1 to L3 vertebrae. MRI revealed significant canal and lateral recess stenosis secondary to facet hypertrophy. We planned a front-back correction of the anterior and posterior spinal elements. We first performed anterior release at the fused part from L1 to L3 and XLIF at L3/4 and L4/5. Next, the patient was placed in the prone position. Spondylectomy at the L2 vertebra and posterior fusion from T10 to L5 were performed. Postoperative radiographs revealed L1 to L3 kyphosis of 32°. No complications occurred during or after surgery. Postoperatively, the patient's low back pain and neurological claudication were resolved. No worsening of kyphosis was observed 24 months postoperatively. Circumferential decompression of the spinal cord at the apical vertebral level and decompression of lumbar canal stenosis were necessary. Front-back correction of the anterior and posterior spinal elements via spondylectomy and lateral lumbar interbody fusion is a reasonable surgical option for thoracolumbar kyphosis and developmental canal stenosis in patients with achondroplasia.

What monitor can replace the cathode-ray tube for visual stimulation to elicit multifocal electroretinograms?

PubMed

Matsumoto, Celso Soiti; Shinoda, Kei; Matsumoto, Harue; Seki, Keisuke; Nagasaka, Eiichiro; Iwata, Takeshi; Mizota, Atsushi

2014-08-05

To compare a conventional cathode-ray tube (CRT) screen to organic light-emitting diode (OLED) and liquid crystal display (LCD) screens as visual stimulators to elicit multifocal electroretinograms (mfERGs), mfERGs were recorded from seven eyes of seven healthy volunteers (21 ± 2 years). The mfERGs elicited by a conventional CRT screen (S710, Compaq Computer Co.) were compared to those elicited by a studio-grade master OLED monitor (PVM-1741, Sony, Japan) and a conventional LCD (S1721, Flexscan, Eizo Nanao Corp., Japan). The luminance changes of each monitor were measured with a photodiode. CRT, OLED, and LCD screens with a frame frequency of 60 Hz were studied. A hexagonal stimulus array with 61 stimulus elements was created on each monitor. The serial white stimuli of the OLED screen at 60 Hz did not fuse, and that of the LCD screens fused. The amplitudes of P1 and P2 of the first-order kernels of the mfERGs were not significantly different from those elicited by the CRT and OLED screens, and the P1 amplitude of the first-order kernel elicited by the LCD stimuli was significantly smaller than that elicited by the CRT in all the groups of the averaged hexagonal elements. The implicit times were approximately 10 ms longer in almost all components elicited by the LCD screen compared to those elicited by the CRT screen. The mfERGs elicited by monitors other than the CRT should be carefully interpreted, especially those elicited by LCD screens. The OLED had good performance, and we conclude that it can replace the CRT as a stimulator for mfERGs; however, a collection of normative data is recommended. © 2014 ARVO.

Percutaneous Mitral Valve Dilatation: Single Balloon versus Double Balloon - A Finite Element Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schievano, Silvia; Kunzelman, Karyn; Nicosia, Mark

2009-01-01

Background: Percutaneous mitral valve (MV) dilatation is performed with either a single balloon (SB) or double balloon (DB) technique. The aim of this study was to compare the two balloon system results using the finite element (FE) method. Methods and Results: An established FE model of the MV was modified by fusing the MV leaflet edges at commissure level to simulate a stenotic valve (orifice area=180mm2). A FE model of a 30mm SB (low-pressure, elastomeric balloon) and an 18mm DB system (high-pressure, non-elastic balloon) was created. Both SB and DB simulations resulted in splitting of the commissures and subsequent stenosismore » dilatation (final MV area=610mm2 and 560mm2 respectively). Stresses induced by the two balloon systems varied across the valve. At the end of inflation, SB showed higher stresses in the central part of the leaflets and at the commissures compared to DB simulation, which demonstrated a more uniform stress distribution. The higher stresses in the SB analysis were due to the mismatch of the round balloon shape with the oval mitral orifice. The commissural split was not easily accomplished with the SB due to its high compliance. The high pressure applied to the DB guaranteed the commissural split even when high forces were required to break the commissure welds. Conclusions: The FE model demonstrated that MV dilatation can be accomplished by both SB and DB techniques. However, the DB method resulted in higher probability of splitting of the fused commissures and less damage caused to the MV leaflets by overstretching.« less

Preparation of calibration materials for microanalysis of Ti minerals by direct fusion of synthetic and natural materials: experience with LA-ICP-MS analysis of some important minor and trace elements in ilmenite and rutile.

PubMed

Odegård, M; Mansfeld, J; Dundas, S H

2001-08-01

Calibration materials for microanalysis of Ti minerals have been prepared by direct fusion of synthetic and natural materials by resistance heating in high-purity graphite electrodes. Synthetic materials were FeTiO3 and TiO2 reagents doped with minor and trace elements; CRMs for ilmenite, rutile, and a Ti-rich magnetite were used as natural materials. Problems occurred during fusion of Fe2O3-rich materials, because at atmospheric pressure Fe2O3 decomposes into Fe3O4 and O2 at 1462 degrees C. An alternative fusion technique under pressure was tested, but the resulting materials were characterized by extensive segregation and development of separate phases. Fe2O3-rich materials were therefore fused below this temperature, resulting in a form of sintering, without conversion of the materials into amorphous glasses. The fused materials were studied by optical microscopy and EPMA, and tested as calibration materials by inductively coupled plasma mass spectrometry, equipped with laser ablation for sample introduction (LA-ICP-MS). It was demonstrated that calibration curves based on materials of rutile composition, within normal analytical uncertainty, generally coincide with calibration curves based on materials of ilmenite composition. It is, therefore, concluded that LA-ICP-MS analysis of Ti minerals can with advantage be based exclusively on calibration materials prepared for rutile, thereby avoiding the special fusion problems related to oxide mixtures of ilmenite composition. It is documented that sintered materials were in good overall agreement with homogeneous glass materials, an observation that indicates that in other situations also sintered mineral concentrates might be a useful alternative for instrument calibration, e.g. as alternative to pressed powders.

Description of the chimaerid jaw and its phylogenetic origins.

PubMed

Grogan, Eileen D; Lund, Richard; Didier, Dominique

1999-01-01

Anatomical delineation of the holocephalan palatoquadrate has proven to be difficult and, so, has been an extensively debated topic as it relates to the evolutionary derivation of jaws, modes of jaw suspension, and the interrelationships of the hondrichthyes (Elasmobranchii and Holocephali). Embryological analyses of the chimaerid jaw and cranium are presented to provide an anatomical description of the palatoquadrate in modern chimaerids. The palatoquadrate fuses, anteriorly, to the nasal capsule early in development. This marks the first point of contact between the mandibular arch and cranium. Orbitonasal canal foramina delineate the dorsal palatoquadrate margin. The posteriormost margin is marked by fusion of the upper jaw with trabecular and parachordal cartilages in the region of the efferent eudobranchial artery foramen and by a suborbitally positioned basitrabecular cartilage. This basitrabecula generates a subocular shelf as it fuses medially to the parachordal cartilage and posteriorly to the postorbital wall and cranial otic process. The results of these analyses are related to morphological studies of Paleozoic chondrichthyan fishes, particularly the autodiastylic paraselachians that represent morphological intermediates to selachians and holocephalans. The paraselachian basitrabecular, which was mechanically fundamental to stabilizing the free autodiastylic upper jaw and a hyoid operculum, is shown to correlate with the suborbital basitrabecular of today's chimaerids. Further analyses of both extant and fossil data permit us to conclude that the primordial chondrichthyan palatoquadrate did not extend posteriorly to include a palatoquadrate-derived otic process. Rather, the posteriormost extent of this element is primitively found within the limits of the orbit and is demarcated by the highly conserved basitrabecular element. The collective analyses support autodiastyly as the ancestral condition from which all fundamental suspensorial states are derived. J. Morphol. 239:45-59, 1999. © 1999 Wiley-Liss, Inc. Copyright © 1999 Wiley-Liss, Inc.

Acoustoelectric current saturation in c-axis fiber-textured polycrystalline zinc oxide films

NASA Astrophysics Data System (ADS)

Pompe, T.; Srikant, V.; Clarke, D. R.

1996-12-01

Acoustoelectric current saturation, which until now has only been observed in piezoelectric single crystals, is observed in thin polycrystalline zinc oxide films. Epitaxial ZnO films on c-plane sapphire and textured ZnO polycrystalline films on fused silica both exhibit current saturation phenomenon. The values of the saturation current densities are in the range 105-106 A/cm2, depending on the carrier concentration in the film, with corresponding saturation electric fields of 3-5×103 V/cm. In addition to the current saturation, the electrical properties of the films degraded with the onset of the acoustoelectric effect but could be restored by annealing at 250 °C in a vacuum for 30 min.

Co-fuse: a new class discovery analysis tool to identify and prioritize recurrent fusion genes from RNA-sequencing data.

PubMed

Paisitkriangkrai, Sakrapee; Quek, Kelly; Nievergall, Eva; Jabbour, Anissa; Zannettino, Andrew; Kok, Chung Hoow

2018-06-07

Recurrent oncogenic fusion genes play a critical role in the development of various cancers and diseases and provide, in some cases, excellent therapeutic targets. To date, analysis tools that can identify and compare recurrent fusion genes across multiple samples have not been available to researchers. To address this deficiency, we developed Co-occurrence Fusion (Co-fuse), a new and easy to use software tool that enables biologists to merge RNA-seq information, allowing them to identify recurrent fusion genes, without the need for exhaustive data processing. Notably, Co-fuse is based on pattern mining and statistical analysis which enables the identification of hidden patterns of recurrent fusion genes. In this report, we show that Co-fuse can be used to identify 2 distinct groups within a set of 49 leukemic cell lines based on their recurrent fusion genes: a multiple myeloma (MM) samples-enriched cluster and an acute myeloid leukemia (AML) samples-enriched cluster. Our experimental results further demonstrate that Co-fuse can identify known driver fusion genes (e.g., IGH-MYC, IGH-WHSC1) in MM, when compared to AML samples, indicating the potential of Co-fuse to aid the discovery of yet unknown driver fusion genes through cohort comparisons. Additionally, using a 272 primary glioma sample RNA-seq dataset, Co-fuse was able to validate recurrent fusion genes, further demonstrating the power of this analysis tool to identify recurrent fusion genes. Taken together, Co-fuse is a powerful new analysis tool that can be readily applied to large RNA-seq datasets, and may lead to the discovery of new disease subgroups and potentially new driver genes, for which, targeted therapies could be developed. The Co-fuse R source code is publicly available at https://github.com/sakrapee/co-fuse .

Practical comparison of 2.7 microm fused-core silica particles and porous sub-2 microm particles for fast separations in pharmaceutical process development.

PubMed

Abrahim, Ahmed; Al-Sayah, Mohammad; Skrdla, Peter; Bereznitski, Yuri; Chen, Yadan; Wu, Naijun

2010-01-05

Fused-core silica stationary phases represent a key technological advancement in the arena of fast HPLC separations. These phases are made by fusing a 0.5 microm porous silica layer onto 1.7 microm nonporous silica cores. The reduced intra-particle flow path of the fused particles provides superior mass transfer kinetics and better performance at high mobile phase velocities, while the fused-core particles provide lower pressure than sub-2 microm particles. In this work, chromatographic performance of the fused-core particles (Ascentis Express) was investigated and compared to that of sub-2 microm porous particles (1.8 microm Zorbax Eclipse Plus C18 and 1.7 microm Acquity BEH C18). Specifically, retention, selectivity, and loading capacity were systematically compared for these two types of columns. Other chromatographic parameters such as efficiency and pressure drop were also studied. Although the fused-core column was found to provide better analyte shape selectivity, both columns had similar hydrophobic, hydrogen bonding, total ion-exchange, and acidic ion-exchange selectivities. As expected, the retention factors and sample loading capacity on the fused-core particle column were slightly lower than those for the sub-2 microm particle column. However, the most dramatic observation was that similar efficiency separations to the sub-2 microm particles could be achieved using the fused-core particles, without the expense of high column back pressure. The low pressure of the fused-core column allows fast separations to be performed routinely on a conventional LC system without significant loss in efficiency or resolution. Applications to the HPLC impurity profiling of drug substance candidates were performed using both types of columns to validate this last point.

Both positive and negative regulatory elements mediate expression of a photoregulated CAB gene from Nicotiana plumbaginifolia.

PubMed Central

Castresana, C; Garcia-Luque, I; Alonso, E; Malik, V S; Cashmore, A R

1988-01-01

We have analyzed promoter regulatory elements from a photoregulated CAB gene (Cab-E) isolated from Nicotiana plumbaginifolia. These studies have been performed by introducing chimeric gene constructs into tobacco cells via Agrobacterium tumefaciens-mediated transformation. Expression studies on the regenerated transgenic plants have allowed us to characterize three positive and one negative cis-acting elements that influence photoregulated expression of the Cab-E gene. Within the upstream sequences we have identified two positive regulatory elements (PRE1 and PRE2) which confer maximum levels of photoregulated expression. These sequences contain multiple repeated elements related to the sequence-ACCGGCCCACTT-. We have also identified within the upstream region a negative regulatory element (NRE) extremely rich in AT sequences, which reduces the level of gene expression in the light. We have defined a light regulatory element (LRE) within the promoter region extending from -396 to -186 bp which confers photoregulated expression when fused to a constitutive nopaline synthase ('nos') promoter. Within this region there is a 132-bp element, extending from -368 to -234 bp, which on deletion from the Cab-E promoter reduces gene expression from high levels to undetectable levels. Finally, we have demonstrated for a full length Cab-E promoter conferring high levels of photoregulated expression, that sequences proximal to the Cab-E TATA box are not replaceable by corresponding sequences from a 'nos' promoter. This contrasts with the apparent equivalence of these Cab-E and 'nos' TATA box-proximal sequences in truncated promoters conferring low levels of photoregulated expression. Images PMID:2901343

Morphological evaluation of maxillary second molars with fused roots: a micro-CT study.

PubMed

Ordinola-Zapata, R; Martins, J N R; Bramante, C M; Villas-Boas, M H; Duarte, M H; Versiani, M A

2017-12-01

To evaluate the internal and external morphologies of fused-rooted maxillary second molars by means of micro-computed tomography (micro-CT) analysis. A total of 100 fused-rooted maxillary second molars from a Brazilian subpopulation were divided into six groups according to the root morphology. The samples were scanned at a resolution of 19.6 μm and evaluated with regard to the external morphology of the roots, the root canal configuration, the percentage frequency of C-shaped canals and isthmuses, as well as the morphology of the root canal system at 1, 2 and 3 mm from the anatomical apex of the fused roots. The most prevalent root canal fusions were type 1, mesiobuccal root fused with distobuccal root (32%), followed by type 3, DB root fused with P root (27%), and type 4, MB root fused with DB root, and P root fused with MB or DB roots (21%). The prevalence of C-shaped root canal systems were 22%. Depending on the type of root fusion, the percentage frequency of isthmuses in the apical level varied from 9.3% to 42.8%, whilst the presence of apical deltas ranged from 18.5% to 57.1% of teeth. The root canal system of maxillary second molars with fused roots may have a high incidence of merging canals, isthmuses, apical deltas and C-shaped configurations. © 2017 International Endodontic Journal. Published by John Wiley & Sons Ltd.

Application of linker technique to trap transiently interacting protein complexes for structural studies

PubMed Central

Reddy Chichili, Vishnu Priyanka; Kumar, Veerendra; Sivaraman, J.

2016-01-01

Protein-protein interactions are key events controlling several biological processes. We have developed and employed a method to trap transiently interacting protein complexes for structural studies using glycine-rich linkers to fuse interacting partners, one of which is unstructured. Initial steps involve isothermal titration calorimetry to identify the minimum binding region of the unstructured protein in its interaction with its stable binding partner. This is followed by computational analysis to identify the approximate site of the interaction and to design an appropriate linker length. Subsequently, fused constructs are generated and characterized using size exclusion chromatography and dynamic light scattering experiments. The structure of the chimeric protein is then solved by crystallization, and validated both in vitro and in vivo by substituting key interacting residues of the full length, unlinked proteins with alanine. This protocol offers the opportunity to study crucial and currently unattainable transient protein interactions involved in various biological processes. PMID:26985443

High-harmonic generation in amorphous solids

DOE Office of Scientific and Technical Information (OSTI.GOV)

You, Yong Sing; Yin, Yanchun; Wu, Yi

High-harmonic generation in isolated atoms and molecules has been widely utilized in extreme ultraviolet photonics and attosecond pulse metrology. Recently, high-harmonic generation has been observed in solids, which could lead to important applications such as all-optical methods to image valance charge density and reconstruct electronic band structures, as well as compact extreme ultraviolet light sources. So far these studies are confined to crystalline solids; therefore, decoupling the respective roles of long-range periodicity and high density has been challenging. Here we report the observation of high-harmonic generation from amorphous fused silica. We also decouple the role of long-range periodicity by comparingmore » harmonics generated from fused silica and crystalline quartz, which contain the same atomic constituents but differ in long-range periodicity. These results advance current understanding of the strong-field processes leading to high-harmonic generation in solids with implications for the development of robust and compact extreme ultraviolet light sources.« less

In-situ short circuit protection system and method for high-energy electrochemical cells

DOEpatents

Gauthier, Michel; Domroese, Michael K.; Hoffman, Joseph A.; Lindeman, David D.; Noel, Joseph-Robert-Gaetan; Radewald, Vern E.; Rouillard, Jean; Rouillard, Roger; Shiota, Toshimi; Trice, Jennifer L.

2000-01-01

An in-situ thermal management system for an energy storage device. The energy storage device includes a plurality of energy storage cells each being coupled in parallel to common positive and negative connections. Each of the energy storage cells, in accordance with the cell's technology, dimensions, and thermal/electrical properties, is configured to have a ratio of energy content-to-contact surface area such that thermal energy produced by a short-circuit in a particular cell is conducted to a cell adjacent the particular cell so as to prevent the temperature of the particular cell from exceeding a breakdown temperature. In one embodiment, a fuse is coupled in series with each of a number of energy storage cells. The fuses are activated by a current spike capacitively produced by a cell upon occurrence of a short-circuit in the cell, thereby electrically isolating the short-circuited cell from the common positive and negative connections.

In-situ short-circuit protection system and method for high-energy electrochemical cells

DOEpatents

Gauthier, Michel; Domroese, Michael K.; Hoffman, Joseph A.; Lindeman, David D.; Noel, Joseph-Robert-Gaetan; Radewald, Vern E.; Rouillard, Jean; Rouillard, Roger; Shiota, Toshimi; Trice, Jennifer L.

2003-04-15

An in-situ thermal management system for an energy storage device. The energy storage device includes a plurality of energy storage cells each being coupled in parallel to common positive and negative connections. Each of the energy storage cells, in accordance with the cell's technology, dimensions, and thermal/electrical properties, is configured to have a ratio of energy content-to-contact surface area such that thermal energy produced by a short-circuit in a particular cell is conducted to a cell adjacent the particular cell so as to prevent the temperature of the particular cell from exceeding a breakdown temperature. In one embodiment, a fuse is coupled in series with each of a number of energy storage cells. The fuses are activated by a current spike capacitively produced by a cell upon occurrence of a short-circuit in the cell, thereby electrically isolating the short-circuited cell from the common positive and negative connections.

High-harmonic generation in amorphous solids

DOE PAGES

You, Yong Sing; Yin, Yanchun; Wu, Yi; ...

2017-09-28

High-harmonic generation in isolated atoms and molecules has been widely utilized in extreme ultraviolet photonics and attosecond pulse metrology. Recently, high-harmonic generation has been observed in solids, which could lead to important applications such as all-optical methods to image valance charge density and reconstruct electronic band structures, as well as compact extreme ultraviolet light sources. So far these studies are confined to crystalline solids; therefore, decoupling the respective roles of long-range periodicity and high density has been challenging. Here we report the observation of high-harmonic generation from amorphous fused silica. We also decouple the role of long-range periodicity by comparingmore » harmonics generated from fused silica and crystalline quartz, which contain the same atomic constituents but differ in long-range periodicity. These results advance current understanding of the strong-field processes leading to high-harmonic generation in solids with implications for the development of robust and compact extreme ultraviolet light sources.« less

The Effect of Drycleaning Moisture on Fused Cloth Systems

DTIC Science & Technology

1989-03-01

TECHNICAL REPORT NATICK/TR-89/024 et, THE EFFECT OF DRYCLEANING MOISTURE ON FUSED CLOTH SYSTEMS BY ELIZABETH J. MORELAND International...MOISTUP.E ON FUSED CLOTH SYSTEMS 12. PERSONAL AUTMOR(S) Elizabeth J. MorelanJ 13«. TYPE OF REPORT Final Technical Report 13b. TIME COVERED...This project was initiated to investigate the effect of moisture in drycleaning systems on preselected fused cloth structures. Adverse surface

Pituitary transcription factor Prop-1 stimulates porcine pituitary glycoprotein hormone alpha subunit gene expression.

PubMed

Sato, Takanobu; Kitahara, Kousuke; Susa, Takao; Kato, Takako; Kato, Yukio

2006-10-01

Recently, we have reported that a Prophet of Pit-1 homeodomain factor, Prop-1, is a novel transcription factor for the porcine follicle-stimulating hormone beta subunit (FSHbeta) gene. This study subsequently aimed to examine the role of Prop-1 in the gene expression of two other porcine gonadotropin subunits, pituitary glycoprotein hormone alpha subunit (alphaGSU), and luteinizing hormone beta subunit (LHbeta). A series of deletion mutants of the porcine alphaGSU (up to -1059 bp) and LHbeta (up to -1277 bp) promoters were constructed in the reporter vector, fused with the secreted alkaline phosphatase gene (pSEAP2-Basic). Transient transfection studies using GH3 cells were carried out to estimate the activation of the porcine alphaGSU and LHbeta promoters by Prop-1, which was found to activate the alphaGSU promoter of -1059/+12 bp up to 11.7-fold but not the LHbeta promoter. Electrophoretic mobility shift assay and DNase I footprinting analysis revealed that Prop-1 binds to six positions, -1038/-1026, -942/-928, -495/-479, -338/-326, -153/-146, and -131/-124 bp, that comprise the A/T cluster. Oligonucleotides of six Prop-1 binding sites were directly connected to the minimum promoter of alphaGSU, fused in the pSEAP2-Basic vector, followed by transfecting GH3 cells to determine the cis-acting activity. Finally, we concluded that at least five Prop-1 binding sites are the cis-acting elements for alphaGSU gene expression. The present results revealed a notable feature of the proximal region, where three Prop-1-binding sites are close to and/or overlap the pituitary glycoprotein hormone basal element, GATA-binding element, and junctional regulatory element. To our knowledge, this is the first demonstration of the role of Prop-1 in the regulation of alphaGSU gene expression. These results, taken together with our previous finding that Prop-1 is a transcription factor for FSHbeta gene, confirm that Prop-1 modulates the synthesis of FSH at the transcriptional level. On the other hand, the defects of Prop-1 are known to cause dwarfism and combined pituitary hormone deficiency accompanying hypogonadism. Accordingly, the present observations provide a novel view to understand the hypogonadism caused by Prop-1 defects at the molecular level through the regulatory mechanism of alphaGSU and FSHbeta gene expressions.

Gradient-based multiresolution image fusion.

PubMed

Petrović, Valdimir S; Xydeas, Costas S

2004-02-01

A novel approach to multiresolution signal-level image fusion is presented for accurately transferring visual information from any number of input image signals, into a single fused image without loss of information or the introduction of distortion. The proposed system uses a "fuse-then-decompose" technique realized through a novel, fusion/decomposition system architecture. In particular, information fusion is performed on a multiresolution gradient map representation domain of image signal information. At each resolution, input images are represented as gradient maps and combined to produce new, fused gradient maps. Fused gradient map signals are processed, using gradient filters derived from high-pass quadrature mirror filters to yield a fused multiresolution pyramid representation. The fused output image is obtained by applying, on the fused pyramid, a reconstruction process that is analogous to that of conventional discrete wavelet transform. This new gradient fusion significantly reduces the amount of distortion artefacts and the loss of contrast information usually observed in fused images obtained from conventional multiresolution fusion schemes. This is because fusion in the gradient map domain significantly improves the reliability of the feature selection and information fusion processes. Fusion performance is evaluated through informal visual inspection and subjective psychometric preference tests, as well as objective fusion performance measurements. Results clearly demonstrate the superiority of this new approach when compared to conventional fusion systems.

Hole-assisted fiber based fiber fuse terminator supporting 22 W input

NASA Astrophysics Data System (ADS)

Tsujikawa, Kyozo; Kurokawa, Kenji; Hanzawa, Nobutomo; Nozoe, Saki; Matsui, Takashi; Nakajima, Kazuhide

2018-05-01

We investigated the air hole structure in hole-assisted fiber (HAF) with the aim of terminating fiber fuse propagation. We focused on two structural parameters c/MFD and S1/S2, which are related respectively to the position and area of the air holes, and mapped their appropriate values for terminating fiber fuse propagation. Here, MFD is the mode field diameter, c is the diameter of an inscribed circle linking the air holes, S1 is the total area of the air holes, and S2 is the area of a circumscribed circle linking the air holes. On the basis of these results, we successfully realized a compact fiber fuse terminator consisting of a 1.35 mm-long HAF, which can terminate fiber fuse propagation even with a 22 W input. In addition, we observed fiber fuse termination using a high-speed camera. We additionally confirmed that the HAF-based fiber fuse terminator is effective under various input power conditions. The penetration length of the optical discharge in the HAF was only less than 300 μm when the input power was from 2 to 22 W.

Barrier breaching device

DOEpatents

Honodel, Charles A.

1985-01-01

A barrier breaching device that is designed primarily for opening holes in interior walls of buildings uses detonating fuse for explosive force. The fuse acts as the ribs or spokes of an umbrella-like device that may be opened up to form a cone. The cone is placed against the wall so that detonating fuse that rings the base of the device and which is ignited by the spoke-like fuses serves to cut a circular hole in the wall.

Barrier breaching device

DOEpatents

Honodel, C.A.

1983-06-01

A barrier breaching device that is designed primarily for opening holes in interior walls of buildings uses detonating fuse for explosive force. The fuse acts as the ribs or spokes of an umbrella-like device that may be opened up to form a cone. The cone is placed against the wall so that detonating fuse that rings the base of the device and which is ignited by the spoke-like fuses serves to cut a circular hole in the wall.

Quantification of Residual Stress from Photonic Signatures of Fused Silica

NASA Technical Reports Server (NTRS)

Cramer, K. Elliott; Hayward, Maurice; Yost, William E.

2013-01-01

A commercially available grey-field polariscope (GFP) instrument for photoelastic examination is used to assess impact damage inflicted upon the outer-most pane of Space Shuttle windows made from fused silica. A method and apparatus for calibration of the stress-optic coefficient using four-point bending is discussed. The results are validated on known material (acrylic) and are found to agree with literature values to within 6%. The calibration procedure is then applied to fused-silica specimens and the stress-optic coefficient is determined to be 2.43 +/- 0.54 x 10(exp -12)/Pa. Fused silica specimens containing impacts artificially made at NASA's Hypervelocity Impact Technology Facility (HIT-F), to simulate damage typical during space flight, are examined. The damage sites are cored from fused silica window carcasses and examined with the GFP. The calibrated GFP measurements of residual stress patterns surrounding the damage sites are presented. Keywords: Glass, fused silica, photoelasticity, residual stress

Dibenzo[a,f]perylene bisimide: effects of introducing two fused rings.

PubMed

Chaolumen; Enno, Hiroki; Murata, Michihisa; Wakamiya, Atsushi; Murata, Yasujiro

2014-11-01

Perylene bisimides (PBIs) are fascinating dyes with various potential applications. To study the effects of introducing a dibenzo-fused structure to the perylene moiety, π-extended PBI derivatives with a dibenzo-fused structure at both of the a and f bonds were synthesized. The twisted structure was characterized by X-ray crystal structure analysis. In the cyclic voltammograms, the dibenzo[a,f]-fused PBI showed a reversible oxidation wave at much less positive potential, relative to a dibenzo[a,o]-fused PBI derivative. These data indicated that two ring fusions at both sides of a naphthalene moiety, which construct a tetracene core, effectively raise the HOMO level compared to fusion of one ring at each naphthalene moiety (two anthracene cores). The dibenzo[a,f]-fused PBI derivative showed an absorption band at 735 nm with a shoulder band reaching 900 nm. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Comparing monolithic and fused core HPLC columns for fast chromatographic analysis of fat-soluble vitamins.

PubMed

Kurdi, Said El; Muaileq, Dina Abu; Alhazmi, Hassan A; Bratty, Mohammed Al; Deeb, Sami El

2017-06-27

HPLC stationary phases of monolithic and fused core type can be used to achieve fast chromatographic separation as an alternative to UPLC. In this study, monolithic and fused core stationary phases are compared for fast separation of four fat-soluble vitamins. Three new methods on the first and second generation monolithic silica RP-18e columns and a fused core pentafluoro-phenyl propyl column were developed. Application of three fused core columns offered comparable separations of retinyl palmitate, DL-α-tocopheryl acetate, cholecalciferol and menadione in terms of elution speed and separation efficiency. Separation was achieved in approx. 5 min with good resolution (Rs > 5) and precision (RSD ≤ 0.6 %). Monolithic columns showed, however, a higher number of theoretical plates, better precision and lower column backpressure than the fused core column. The three developed methods were successfully applied to separate and quantitate fat-soluble vitamins in commercial products.

Lignin-based active anode materials synthesized from low-cost renewable resources

DOEpatents

Rios, Orlando; Tenhaeff, Wyatt Evan; Daniel, Claus; Dudney, Nancy Johnston; Johs, Alexander; Nunnery, Grady Alexander; Baker, Frederick Stanley

2016-06-07

A method of making an anode includes the steps of providing fibers from a carbonaceous precursor, the carbon fibers having a glass transition temperature T.sub.g. In one aspect the carbonaceous precursor is lignin. The carbonaceous fibers are placed into a layered fiber mat. The fiber mat is fused by heating the fiber mat in the presence of oxygen to above the T.sub.g but no more than 20% above the T.sub.g to fuse fibers together at fiber to fiber contact points and without melting the bulk fiber mat to create a fused fiber mat through oxidative stabilization. The fused fiber mat is carbonized by heating the fused fiber mat to at least 650.degree. C. under an inert atmosphere to create a carbonized fused fiber mat. A battery anode formed from carbonaceous precursor fibers is also disclosed.

Interaction between two cis-acting elements, ABRE and DRE, in ABA-dependent expression of Arabidopsis rd29A gene in response to dehydration and high-salinity stresses.

PubMed

Narusaka, Yoshihiro; Nakashima, Kazuo; Shinwari, Zabta K; Sakuma, Yoh; Furihata, Takashi; Abe, Hiroshi; Narusaka, Mari; Shinozaki, Kazuo; Yamaguchi-Shinozaki, Kazuko

2003-04-01

Many abiotic stress-inducible genes contain two cis-acting elements, namely a dehydration-responsive element (DRE; TACCGACAT) and an ABA-responsive element (ABRE; ACGTGG/TC), in their promoter regions. We precisely analyzed the 120 bp promoter region (-174 to -55) of the Arabidopsis rd29A gene whose expression is induced by dehydration, high-salinity, low-temperature, and abscisic acid (ABA) treatments and whose 120 bp promoter region contains the DRE, DRE/CRT-core motif (A/GCCGAC), and ABRE sequences. Deletion and base substitution analyses of this region showed that the DRE-core motif functions as DRE and that the DRE/DRE-core motif could be a coupling element of ABRE. Gel mobility shift assays revealed that DRE-binding proteins (DREB1s/CBFs and DREB2s) bind to both DRE and the DRE-core motif and that ABRE-binding proteins (AREBs/ABFs) bind to ABRE in the 120 bp promoter region. In addition, transactivation experiments using Arabidopsis leaf protoplasts showed that DREBs and AREBs cumulatively transactivate the expression of a GUS reporter gene fused to the 120 bp promoter region of rd29A. These results indicate that DRE and ABRE are interdependent in the ABA-responsive expression of the rd29A gene in response to ABA in Arabidopsis.

30 CFR 75.601-2 - Short circuit protection; use of fuses; approval by the Secretary.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Trailing Cables § 75.601-2 Short circuit protection; use of fuses; approval by the Secretary. Fuses shall not be employed to provide short circuit protection for trailing cables unless specifically approved...

Blast Off into Space Science with Fuses.

ERIC Educational Resources Information Center

Bombaugh, Ruth

2000-01-01

Introduces an activity in which students build a fuse with steel, wood, light bulbs, copper wire, clay, and batteries. Uses the cross-age instructional approach to teach about the value of instructional time. Contains directions for building a fuse. (YDS)

How Does Abundance Affect the Strength of UV Emission in Elliptical Galaxies?

NASA Technical Reports Server (NTRS)

Sonneborn, George (Technical Monitor); Brown, Thomas

2005-01-01

This program used the Far Ultraviolet Spectroscopic Explorer (FUSE) to observe elliptical galaxies with the intention of measuring the chemical abundances in their hot stellar populations. It was designed to complement an earlier FUSE program that observed elliptical galaxies with strong UV emission. The current program originally planned observations of two ellipticals with weak UV emission (M32 and M49). Once FUSE encountered pointing control problems in certain regions of the sky (particularly Virgo, which is very unfortunate for the study of ellipticals in general), M49 was replaced with the bulge of M31, which has a similar UV-to-optical flux ratio as the center of M49. As the closest elliptical galaxy and the one with the weakest UV-to-optical flux ratio, M32 was an obvious choice of target, but M49 was the ideal complementary target, because it has a very low reddening (unlike M32). With the inability of FUSE to point at Virgo, nearly all of the best elliptical galaxies (bright galaxies with low foreground extinction) were also lost, and this severely hampered three FUSE programs of the PI, all focused on the hot stellar populations of ellipticals. M31 was the best replacement for M49, but like M32, it suffers from significant foreground reddening. Strong Galactic ISM lines heavily contaminate the FUSE spectra of M31 and M32. These ISM lines are coincident with the photospheric lines from the stellar populations (whereas M49, with little foreground ISM and significant redshift, would not have suffered from this problem). We have reduced the faint (and thus difficult) data for M31 and M32, producing final co-added spectra representing all of the exposures, but we have not yet finished our analysis, due to the complication of the contaminating ISM. The silver lining here is the set of CHI lines at 1175 Angstroms, which are not significantly contaminated by the ISM. A comparison of the M31 spectrum with other galaxies observed by FEE showed a surprising result: the hot stars in M31 seem to have a similar carbon abundance to those stars in galaxies with much brighter UV emission. The fraction of these hot stars in a population should be a strong function of chemical abundances, so this finding warrants further exploration, and we are proceeding with our analysis. Because the UV emission in these galaxies comes from a population of extreme horizontal branch stars, the PI (Brown) presented this result at a June 2003 conference on such stars.

FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations.

PubMed

Neumann, Manuela; Bentmann, Eva; Dormann, Dorothee; Jawaid, Ali; DeJesus-Hernandez, Mariely; Ansorge, Olaf; Roeber, Sigrun; Kretzschmar, Hans A; Munoz, David G; Kusaka, Hirofumi; Yokota, Osamu; Ang, Lee-Cyn; Bilbao, Juan; Rademakers, Rosa; Haass, Christian; Mackenzie, Ian R A

2011-09-01

Accumulation of the DNA/RNA binding protein fused in sarcoma as cytoplasmic inclusions in neurons and glial cells is the pathological hallmark of all patients with amyotrophic lateral sclerosis with mutations in FUS as well as in several subtypes of frontotemporal lobar degeneration, which are not associated with FUS mutations. The mechanisms leading to inclusion formation and fused in sarcoma-associated neurodegeneration are only poorly understood. Because fused in sarcoma belongs to a family of proteins known as FET, which also includes Ewing's sarcoma and TATA-binding protein-associated factor 15, we investigated the potential involvement of these other FET protein family members in the pathogenesis of fused in sarcoma proteinopathies. Immunohistochemical analysis of FET proteins revealed a striking difference among the various conditions, with pathology in amyotrophic lateral sclerosis with FUS mutations being labelled exclusively for fused in sarcoma, whereas fused in sarcoma-positive inclusions in subtypes of frontotemporal lobar degeneration also consistently immunostained for TATA-binding protein-associated factor 15 and variably for Ewing's sarcoma. Immunoblot analysis of proteins extracted from post-mortem tissue of frontotemporal lobar degeneration with fused in sarcoma pathology demonstrated a relative shift of all FET proteins towards insoluble protein fractions, while genetic analysis of the TATA-binding protein-associated factor 15 and Ewing's sarcoma gene did not identify any pathogenic variants. Cell culture experiments replicated the findings of amyotrophic lateral sclerosis with FUS mutations by confirming the absence of TATA-binding protein-associated factor 15 and Ewing's sarcoma alterations upon expression of mutant fused in sarcoma. In contrast, all endogenous FET proteins were recruited into cytoplasmic stress granules upon general inhibition of Transportin-mediated nuclear import, mimicking the findings in frontotemporal lobar degeneration with fused in sarcoma pathology. These results allow a separation of fused in sarcoma proteinopathies caused by FUS mutations from those without a known genetic cause based on neuropathological features. More importantly, our data imply different pathological processes underlying inclusion formation and cell death between both conditions; the pathogenesis in amyotrophic lateral sclerosis with FUS mutations appears to be more restricted to dysfunction of fused in sarcoma, while a more global and complex dysregulation of all FET proteins is involved in the subtypes of frontotemporal lobar degeneration with fused in sarcoma pathology.

Measuring In-Situ Mdf Velocity Of Detonation

DOEpatents

Horine, Frank M.; James, Jr., Forrest B.

2005-10-25

A system for determining the velocity of detonation of a mild detonation fuse mounted on the surface of a device includes placing the device in a predetermined position with respect to an apparatus that carries a couple of sensors that sense the passage of a detonation wave at first and second spaced locations along the fuse. The sensors operate a timer and the time and distance between the locations is used to determine the velocity of detonation. The sensors are preferably electrical contacts that are held spaced from but close to the fuse such that expansion of the fuse caused by detonation causes the fuse to touch the contact, causing an electrical signal to actuate the timer.

SINA: A test system for proximity fuses

NASA Astrophysics Data System (ADS)

Ruizenaar, M. G. A.

1989-04-01

SINA, a signal generator that can be used for testing proximity fuses, is described. The circuitry of proximity fuses is presented; the output signal of the RF circuit results from a mixing of the emitted signal and received signal that is Doppler shifted in frequency by the relative motion of the fuse with respect to the reflecting target of surface. With SINA, digitized and stored target and clutter signals (previously measured) can be transformed to Doppler signals, for example during a real flight. SINA can be used for testing fuse circuitry, for example in the verification of results of computer simulations of the low frequency Doppler signal processing. The software of SINA and its use are explained.

Enhanced image fusion using directional contrast rules in fuzzy transform domain.

PubMed

Nandal, Amita; Rosales, Hamurabi Gamboa

2016-01-01

In this paper a novel image fusion algorithm based on directional contrast in fuzzy transform (FTR) domain is proposed. Input images to be fused are first divided into several non-overlapping blocks. The components of these sub-blocks are fused using directional contrast based fuzzy fusion rule in FTR domain. The fused sub-blocks are then transformed into original size blocks using inverse-FTR. Further, these inverse transformed blocks are fused according to select maximum based fusion rule for reconstructing the final fused image. The proposed fusion algorithm is both visually and quantitatively compared with other standard and recent fusion algorithms. Experimental results demonstrate that the proposed method generates better results than the other methods.

Development of thermocouple generators for small-caliber munitions fuze. Phase I. Final report, 1 Feb--3 Sep 1974. [Aerodynamically heated thermoelectric converters to power rf proximity fuses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eggers, P.E.

1975-03-01

An analytical study has been performed to assess the feasibility of using aerodynamically heated thermoelectric convertors to power RF proximity fuzes. The collective results of this study indicate that such a thermoelectric power supply is feasible for use with 20 mm projectiles and is compatible with the existing RF fuze circuit and safe arming distance requirements. A disc module concept has evolved from this study involving thin-film bismuth telluride as the basic thermoelectric element. Preliminary experimental studies were completed in order to identify principal parameters for the bismuth telluride.

Some properties of human neuronal alpha 7 nicotinic acetylcholine receptors fused to the green fluorescent protein.

PubMed

Palma, Eleonora; Mileo, Anna M; Martinez-Torres, Ataulfo; Eusebi, Fabrizio; Miledi, Ricardo

2002-03-19

The functional properties and cellular localization of the human neuronal alpha7 nicotinic acetylcholine (AcCho) receptor (alpha7 AcChoR) and its L248T mutated (mut) form were investigated by expressing them alone or as gene fusions with the enhanced version of the green fluorescent protein (GFP). Xenopus oocytes injected with wild-type (wt), mutalpha7, or the chimeric subunit cDNAs expressed receptors that gated membrane currents when exposed to AcCho. As already known, AcCho currents generated by wtalpha7 receptors decay much faster than those elicited by the mutalpha7 receptors. Unexpectedly, the fusion of GFP to the wt and mutated alpha7 receptors led to opposite results: the AcCho-current decay of the wt receptors became slower, whereas that of the mutated receptors was accelerated. Furthermore, repetitive applications of AcCho led to a considerable "run-down" of the AcCho currents generated by mutalpha7-GFP receptors, whereas those of the wtalpha7-GFP receptors remained stable or increased in amplitude. The AcCho-current run-down of mutalpha7-GFP oocytes was accompanied by a marked decrease of alpha-bungarotoxin binding activity. Fluorescence, caused by the chimeric receptors expressed, was seen over the whole oocyte surface but was more intense and abundant in the animal hemisphere, whereas it was much weaker in the vegetal hemisphere. We conclude that fusion of GFP to wtalpha7 and mutalpha7 receptors provides powerful tools to study the distribution and function of alpha7 receptors. We also conclude that fused genes do not necessarily recapitulate all of the properties of the original receptors. This fact must be borne close in mind whenever reporter genes are attached to proteins.

Lithium-Ion Small Cell Battery Shorting Study

NASA Technical Reports Server (NTRS)

Pearson, Chris; Curzon, David; Blackmore, Paul; Rao, Gopalakrishna

2004-01-01

AEA performed a hard short study on various cell configurations whilst monitoring voltage, current and temperature. Video recording was also done to verify the evidence for cell venting. The presentation summarizes the results of the study including video footage of typical samples. Need for the diode protection in manned applications is identified. The standard AEA approach of using fused connectors during AIT for unmanned applications is also described.

Two negative cis-regulatory regions involved in fruit-specific promoter activity from watermelon (Citrullus vulgaris S.).

PubMed

Yin, Tao; Wu, Hanying; Zhang, Shanglong; Lu, Hongyu; Zhang, Lingxiao; Xu, Yong; Chen, Daming; Liu, Jingmei

2009-01-01

A 1.8 kb 5'-flanking region of the large subunit of ADP-glucose pyrophosphorylase, isolated from watermelon (Citrullus vulgaris S.), has fruit-specific promoter activity in transgenic tomato plants. Two negative regulatory regions, from -986 to -959 and from -472 to -424, were identified in this promoter region by fine deletion analyses. Removal of both regions led to constitutive expression in epidermal cells. Gain-of-function experiments showed that these two regions were sufficient to inhibit RFP (red fluorescent protein) expression in transformed epidermal cells when fused to the cauliflower mosaic virus (CaMV) 35S minimal promoter. Gel mobility shift experiments demonstrated the presence of leaf nuclear factors that interact with these two elements. A TCCAAAA motif was identified in these two regions, as well as one in the reverse orientation, which was confirmed to be a novel specific cis-element. A quantitative beta-glucuronidase (GUS) activity assay of stable transgenic tomato plants showed that the activities of chimeric promoters harbouring only one of the two cis-elements, or both, were approximately 10-fold higher in fruits than in leaves. These data confirm that the TCCAAAA motif functions as a fruit-specific element by inhibiting gene expression in leaves.

Two negative cis-regulatory regions involved in fruit-specific promoter activity from watermelon (Citrullus vulgaris S.)

PubMed Central

Yin, Tao; Wu, Hanying; Zhang, Shanglong; Liu, Jingmei; Lu, Hongyu; Zhang, Lingxiao; Xu, Yong; Chen, Daming

2009-01-01

A 1.8 kb 5′-flanking region of the large subunit of ADP-glucose pyrophosphorylase, isolated from watermelon (Citrullus vulgaris S.), has fruit-specific promoter activity in transgenic tomato plants. Two negative regulatory regions, from –986 to –959 and from –472 to –424, were identified in this promoter region by fine deletion analyses. Removal of both regions led to constitutive expression in epidermal cells. Gain-of-function experiments showed that these two regions were sufficient to inhibit RFP (red fluorescent protein) expression in transformed epidermal cells when fused to the cauliflower mosaic virus (CaMV) 35S minimal promoter. Gel mobility shift experiments demonstrated the presence of leaf nuclear factors that interact with these two elements. A TCCAAAA motif was identified in these two regions, as well as one in the reverse orientation, which was confirmed to be a novel specific cis-element. A quantitative β-glucuronidase (GUS) activity assay of stable transgenic tomato plants showed that the activities of chimeric promoters harbouring only one of the two cis-elements, or both, were ∼10-fold higher in fruits than in leaves. These data confirm that the TCCAAAA motif functions as a fruit-specific element by inhibiting gene expression in leaves. PMID:19073962

Distal-less induces elemental color patterns in Junonia butterfly wings.

PubMed

Dhungel, Bidur; Ohno, Yoshikazu; Matayoshi, Rie; Iwasaki, Mayo; Taira, Wataru; Adhikari, Kiran; Gurung, Raj; Otaki, Joji M

2016-01-01

The border ocellus, or eyespot, is a conspicuous color pattern element in butterfly wings. For two decades, it has been hypothesized that transcription factors such as Distal-less (Dll) are responsible for eyespot pattern development in butterfly wings, based on their expression in the prospective eyespots. In particular, it has been suggested that Dll is a determinant for eyespot size. However, functional evidence for this hypothesis has remained incomplete, due to technical difficulties. Here, we show that ectopically expressed Dll induces ectopic elemental color patterns in the adult wings of the blue pansy butterfly, Junonia orithya (Lepidoptera, Nymphalidae). Using baculovirus-mediated gene transfer, we misexpressed Dll protein fused with green fluorescent protein (GFP) in pupal wings, resulting in ectopic color patterns, but not the formation of intact eyespots. Induced changes included clusters of black and orange scales (a basic feature of eyespot patterns), black and gray scales, and inhibition of cover scale development. In contrast, ectopic expression of GFP alone did not induce any color pattern changes using the same baculovirus-mediated gene transfer system. These results suggest that Dll plays an instructive role in the development of color pattern elements in butterfly wings, although Dll alone may not be sufficient to induce a complete eyespot. This study thus experimentally supports the hypothesis of Dll function in eyespot development.

Differentiation of cartilaginous anlage in entire embryonic mouse limbs cultured in a rotating bioreactor.

NASA Astrophysics Data System (ADS)

Duke, P.; Oakley, C.; Montufar-Solis, D.

The embryonic mammalian limb is sensitive both in vivo and in vitro to changes in gravitational force. Hypergravity of centrifugation and microgravity of space decreased size of elements due to precocious or delayed chondrogenesis respectively. In recapitulating spaceflight experiments, premetatarsals were cultured in suspension in a low stress, low sheer rotating bioreactor, and found to be shorter than those cultured in standard culture dishes, and cartilage development was delayed. This study only measured length of the metatarsals, and did not account for possible changes in width and/or in form of the skeletal elements. Shorter cartilage elements in limbbuds cultured in the bioreactor may be due to the ability of the system to reproduce a more in vivo 3D shape than traditional organ cultures. Tissues subjected to traditional organ cultures become flattened by their own weight, attachment to the filter, and restrictions imposed by nutrient diffusion. The purpose of the current experiment was to determine if entire limb buds could be successfully cultured in the bioreactor, and to compare the effects on 3D shape with that of culturing in a culture dish system. Fore and hind limbs from E11-E13 ICR mouse embryos were placed either in the bioreactor, in Trowell culture, or fixed as controls. Limbbuds were cultured for six days, fixed, and processed either as whole mounts or embedded for histology. Qualitative analysis revealed that the Trowell culture specimens were flattened, while bioreactor culture specimens had a more in vivo-like 3D limb shape. Sections of limbbuds from both types of cultures had excellent cartilage differentiation, with apparently more cell maturation, and hypertrophy in the specimens cultured in the bioreactor. Morphometric quantitation of the cartilaginous elements for comparisons of the two culture systems was complicated due to some limb buds fusing together during culture. This problem was especially noticeable in the younger limbs, and may be rectified by embedding the limbs in a matrix (e.g. alginate) to maintain integrity of the tissue while in culture in the bioreactor. The bioreactor supported differentiation of skeletal elements in entire limbs, and maintained better external limb morphology than did the Trowell system. Supported by NIH/NIDCR Training Grant T358DE07252-08.

Rapid fusion between mesenchymal stem cells and cardiomyocytes yields electrically active, non-contractile hybrid cells.

PubMed

Shadrin, Ilya Y; Yoon, Woohyun; Li, Liqing; Shepherd, Neal; Bursac, Nenad

2015-07-10

Cardiac cell therapies involving bone marrow-derived human mesenchymal stem cells (hMSCs) have shown promising results, although their mechanisms of action are still poorly understood. Here, we investigated direct interactions between hMSCs and cardiomyocytes in vitro. Using a genetic Ca(2+) indicator gCaMP3 to efficiently label hMSCs in co-cultures with neonatal rat ventricular myocytes (NRVMs), we determined that 25-40% of hMSCs (from 4 independent donors) acquired periodic Ca(2+) transients and cardiac markers through spontaneous fusion with NRVMs. Sharp electrode and voltage-clamp recordings in fused cells showed action potential properties and Ca(2+) current amplitudes in between those of non-fused hMSCs and NRVMs. Time-lapse video-microscopy revealed the first direct evidence of active fusion between hMSCs and NRVMs within several hours of co-culture. Application of blebbistatin, nifedipine or verapamil caused complete and reversible inhibition of fusion, suggesting potential roles for actomyosin bridging and Ca(2+) channels in the fusion process. Immunostaining for Cx43, Ki67, and sarcomeric α-actinin showed that fused cells remain strongly coupled to surrounding NRVMs, but downregulate sarcomeric structures over time, acquiring a non-proliferative and non-contractile phenotype. Overall, these results describe the phenotype and mechanisms of hybrid cell formation via fusion of hMSCs and cardiomyocytes with potential implications for cardiac cell therapy.

A Widely-Accessible Distributed MEMS Processing Environment. The MEMS Exchange Program

DTIC Science & Technology

2012-10-29

promise for high-aspect and deep etching into fused silica. This process capability is important for a DARPA project called the Navigation-Grade...on fused silica samples that appear to allow 2 to 1 aspect ratios in fused silica with a depth of etch of around 125 microns – a dramatic result in a...very hard to etch material such as fused silica! After receiving approval from DARPA, the MEMS Exchange purchased a previously- owned Ulvac etcher

Refractive index sensors based on the fused tapered special multi-mode fiber

NASA Astrophysics Data System (ADS)

Fu, Xing-hu; Xiu, Yan-li; Liu, Qin; Xie, Hai-yang; Yang, Chuan-qing; Zhang, Shun-yang; Fu, Guang-wei; Bi, Wei-hong

2016-01-01

In this paper, a novel refractive index (RI) sensor is proposed based on the fused tapered special multi-mode fiber (SMMF). Firstly, a section of SMMF is spliced between two single-mode fibers (SMFs). Then, the SMMF is processed by a fused tapering machine, and a tapered fiber structure is fabricated. Finally, a fused tapered SMMF sensor is obtained for measuring external RI. The RI sensing mechanism of tapered SMMF sensor is analyzed in detail. For different fused tapering lengths, the experimental results show that the RI sensitivity can be up to 444.517 81 nm/RIU in the RI range of 1.334 9—1.347 0. The RI sensitivity is increased with the increase of fused tapering length. Moreover, it has many advantages, including high sensitivity, compact structure, fast response and wide application range. So it can be used to measure the solution concentration in the fields of biochemistry, health care and food processing.

Laser-assisted selective fusing of thermal sprayed Ni-based self-fluxing alloys by using high-power diode lasers

NASA Astrophysics Data System (ADS)

Chun, Eun-Joon; Kim, Min-Su; Nishikawa, Hiroshi; Park, Changkyoo; Suh, Jeong

2018-03-01

Fusing treatment of Ni-based self-fluxing alloys (Metco-16C and 1276F) was performed using high-power diode lasers to control the temperature of the substrate's surface in real time. The effects of the fusing treatment temperature on the microstructural change and hardness distribution were also investigated. For Metco-16C and 1276F, the macrostructural inhomogeneity (voids) within the thermal sprayed layer decreased considerably as the fusing temperature increased. For both self-fluxing alloys, the optimal temperature for fusing was approximately 1423 K (for Metco-16C) and 1373 K (for 1276F), both of which are within the solid state temperature range; these temperatures maximize the alloy hardness together with the macrostructural homogeneity. In this temperature range, the microstructure consists of a lamellar-structured matrix phase with fine (<5 μm) carbides and borides. Selective fusing for a thermal sprayed layer 0.2-0.5 mm in thickness could be successfully achieved in a high-power diode laser system.

In situ X-Ray Diffraction of Shock-Compressed Fused Silica

NASA Astrophysics Data System (ADS)

Tracy, Sally June; Turneaure, Stefan J.; Duffy, Thomas S.

2018-03-01

Because of its widespread applications in materials science and geophysics, SiO2 has been extensively examined under shock compression. Both quartz and fused silica transform through a so-called "mixed-phase region" to a dense, low compressibility high-pressure phase. For decades, the nature of this phase has been a subject of debate. Proposed structures include crystalline stishovite, another high-pressure crystalline phase, or a dense amorphous phase. Here we use plate-impact experiments and pulsed synchrotron x-ray diffraction to examine the structure of fused silica shock compressed to 63 GPa. In contrast to recent laser-driven compression experiments, we find that fused silica adopts a dense amorphous structure at 34 GPa and below. When compressed above 34 GPa, fused silica transforms to untextured polycrystalline stishovite. Our results can explain previously ambiguous features of the shock-compression behavior of fused silica and are consistent with recent molecular dynamics simulations. Stishovite grain sizes are estimated to be ˜5 - 30 nm for compression over a few hundred nanosecond time scale.

Bilateral maxillary fused second and third molars: a rare occurrence

PubMed Central

Liang, Rui-Zhen; Wu, Jin-Tao; Wu, You-Nong; Smales, Roger J; Hu, Ming; Yu, Jin-Hua; Zhang, Guang-Dong

2012-01-01

This case report describes the diagnosis and endodontic therapy of maxillary fused second and third molars, using cone-beam computed tomography (CBCT). A 31-year-old Chinese male, with no contributory medical or family/social history, presented with throbbing pain in the maxillary right molar area following an unsuccessful attempted tooth extraction. Clinical examination revealed what appeared initially to be a damaged large extra cusp on the buccal aspect of the distobuccal cusp of the second molar. However, CBCT revealed that a third molar was fused to the second molar. Unexpectedly, the maxillary left third molar also was fused to the second molar, and the crown of an unerupted supernumerary fourth molar was possibly also fused to the apical root region of the second molar. Operative procedures should not be attempted without adequate radiographic investigation. CBCT allowed the precise location of the root canals of the right maxillary fused molar teeth to permit successful endodontic therapy, confirmed after 6 months. PMID:23222992

Bilateral maxillary fused second and third molars: a rare occurrence.

PubMed

Liang, Rui-Zhen; Wu, Jin-Tao; Wu, You-Nong; Smales, Roger J; Hu, Ming; Yu, Jin-Hua; Zhang, Guang-Dong

2012-12-01

This case report describes the diagnosis and endodontic therapy of maxillary fused second and third molars, using cone-beam computed tomography (CBCT). A 31-year-old Chinese male, with no contributory medical or family/social history, presented with throbbing pain in the maxillary right molar area following an unsuccessful attempted tooth extraction. Clinical examination revealed what appeared initially to be a damaged large extra cusp on the buccal aspect of the distobuccal cusp of the second molar. However, CBCT revealed that a third molar was fused to the second molar. Unexpectedly, the maxillary left third molar also was fused to the second molar, and the crown of an unerupted supernumerary fourth molar was possibly also fused to the apical root region of the second molar. Operative procedures should not be attempted without adequate radiographic investigation. CBCT allowed the precise location of the root canals of the right maxillary fused molar teeth to permit successful endodontic therapy, confirmed after 6 months.

Distortion of three-unit implant frameworks during casting, soldering, and simulated porcelain firings.

PubMed

Zervas, P J; Papazoglou, E; Beck, F M; Carr, A B

1999-09-01

The aim of this study was to assess distortion inherent in casting, soldering, and simulated porcelain firings of screw-retained, implant-supported three-unit fixed partial dentures (FPDs). Ten wax patterns were fabricated on a die-stone cast containing two implants, 20 mm apart from center to center. Five specimens were cast in a high-palladium alloy, exposed to simulated porcelain firings, sectioned, and then soldered with low-fusing solder. Five specimens were cast, sectioned, soldered with high-fusing solder, and then exposed to simulated porcelain firings. For each specimen, two horizontal and six vertical distances between appropriately scribed reference points were measured with a traveling microscope. Comparisons were made among the various measurements taken after wax-pattern fabrication, casting, high- and low-fusing soldering, and each porcelain firing. Data were analyzed using a repeated-measures factorial ANOVA (alpha = 0.05). Significant difference was detected in the amount of horizontal distortion during casting (53 +/- 24 microns) and high-fusing soldering (-49 +/- 50 microns), as well as in the amount of horizontal distortion during high-fusing soldering (-49 +/- 50 microns) and low-fusing soldering (17 +/- 26 microns). However, no clinically significant difference was found in the amount of horizontal distortion during casting, low-fusing, and high-fusing soldering. The greatest amount of distortion during the simulated porcelain firings took place during the oxidizing cycle. Soldering did not improve the casting misfit of a three-unit implant-retained FPD model. Metal-ceramic implant frameworks should be oxidized before intraoral fit evaluation.

Towards reproducible experimental studies for non-convex polyhedral shaped particles

NASA Astrophysics Data System (ADS)

Wilke, Daniel N.; Pizette, Patrick; Govender, Nicolin; Abriak, Nor-Edine

2017-06-01

The packing density and flat bottomed hopper discharge of non-convex polyhedral particles are investigated in a systematic experimental study. The motivation for this study is two-fold. Firstly, to establish an approach to deliver quality experimental particle packing data for non-convex polyhedral particles that can be used for characterization and validation purposes of discrete element codes. Secondly, to make the reproducibility of experimental setups as convenient and readily available as possible using affordable and accessible technology. The primary technology for this study is fused deposition modeling used to 3D print polylactic acid (PLA) particles using readily available 3D printer technology. A total of 8000 biodegradable particles were printed, 1000 white particles and 1000 black particles for each of the four particle types considered in this study. Reproducibility is one benefit of using fused deposition modeling to print particles, but an extremely important additional benefit is that specific particle properties can be explicitly controlled. As an example in this study the volume fraction of each particle can be controlled i.e. the effective particle density can be adjusted. In this study the particle volumes reduces drastically as the non-convexity is increased, however all printed white particles in this study have the same mass within 2% of each other.

[The design of Co-Cr-Mo alloy combining the framework with porcelain fused to metal restorations and determination of the mechanical properties].

PubMed

Chao, Yong-lie; Lui, Chang-hong; Li, Ning; Yang, Xiao-yu

2005-02-01

To investigate a kind of Co-Cr-Mo alloys used for both porcelain fused to metal (PFM) restorations and casting framework of removable partial dentures. The Co-Cr-Mo alloy underwent the design for elementary compositions of the alloys and the production from the raw materials by means of a vacuum melt furnace. The strength, hardness, plasticity and casting ability of the alloy were examined with metal tensile test. Vickers hardness test and grid casting were examined respectively. The microstructure of the Co-Cr-Mo alloy was also inspected by scanning electron microscope and X-ray diffraction analysis. The elementary composition of DA9-4 alloy mainly consisted of Co 54%-67%, Cr 21%-26%, Mo 5%-8%, W 5%-8%, Si 1%-3%, Mn 0.1%-0.25% and trace elements. The yield strength of the alloy was 584 MPa, while the tensile strength was 736 MPa. The coefficient of expansion was 15.0%, the Vickers hardness reached 322, and the casting ratio exibited 100%. The DA9-4 Co-Cr-Mo alloy used for PFM and framework shown in this paper can meet the clinical demands and have reached the objects of the experiment plan.

Jones matrix formulation of a Porro prism laser resonator with waveplates: theoretical and experimental analysis

NASA Astrophysics Data System (ADS)

Agrawal, L.; Bhardwaj, A.; Pal, S.; Kumar, A.

2007-11-01

This article presents the results of a detailed theoretical and experimental analysis carried out on a folded Z-shaped polarization coupled, electro-optically Q-switched laser resonator with Porro prisms and waveplates. The advantages of adding waveplates in a Porro prism resonator have been explored for creating high loss condition prior to Q-switching and obtaining variable reflectivity with fixed orientation of Porro prism. Generalized expressions have been derived in terms of azimuth angles and phase shifts introduced by the polarizing elements. These expressions corroborate with known reported results under appropriate substitutions. A specific case of a crossed Porro prism diode-pumped Nd:YAG laser has been theoretically and experimentally investigated. In the feedback arm, a 0.57λ waveplate oriented at 135° completely compensates the phase shift of a fused silica Porro prism and provides better tolerances than a BK-7 prism/0.60λ waveplate combination to stop prelasing. The fused silica prism/0.57λ combination with waveplate at 112° acts like a 100% mirror and was utilized for optimization of free running performance. The effective reflectivity was determined for various orientations of the quarter waveplate in the gain arm to numerically estimate the Q-switched laser pulse parameters through rate equation analysis. Experimental results match well with the theoretical analysis.

Development of a compact optical MEMS scanner with integrated VCSEL light source and diffractive optics

NASA Astrophysics Data System (ADS)

Krygowski, Thomas W.; Reyes, David; Rodgers, M. Steven; Smith, James H.; Warren, Mial E.; Sweatt, William C.; Blum-Spahn, Olga; Wendt, Joel R.; Asbill, Randolph E.

1999-09-01

In this work the design and initial fabrication results are reported for the components of a compact optical-MEMS laser scanning system. This system integrates a silicon MEMS laser scanner, a Vertical Cavity Surface Emitting Laser (VCSEL) and passive optical components. The MEMS scanner and VCSEL are mounted onto a fused silica substrate which serves as an optical interconnect between the devices. Two Diffractive Optical Elements (DOE's) are etched into the fused silica substrate to focus the VCSEL beam and increase the scan range. The silicon MEMS scanner consists of an actuator that continuously scans the position of a large polysilicon gold- coated shuttle containing a third DOE. Interferometric measurements show that the residual stress in the 50 micrometer X 1000 micrometer shuttle is extremely low, with a maximum deflection of only 0.18 micrometer over an 800 micrometer span for an unmetallized case and a deflection of 0.56 micrometer for the metallized case. A conservative estimate for the scan range is approximately plus or minus 4 degrees, with a spot size of about 0.5 mm, producing 50 resolvable spots. The basic system architecture, optical and MEMS design is reported in this paper, with an emphasis on the design and fabrication of the silicon MEMS scanner portion of the system.

Mineralization of the Sea Urchin Skeleton

NASA Astrophysics Data System (ADS)

Wilt, F.

2001-12-01

The sea urchin possess a calcareous skeleton composed of over 99% magnesian calcite,an enveloping extracellular matrix, and an occluded protein matrix. The most intensively studied skeletal element is the spicule of the embryo. At the 32 cell stage of development a cohort of 4 cells becomes irrevocably dedicated to spicule formation. At the early gastrula stage the descendants of these founder cells form the primary mesenchyme (PMC). The PMCs fuse to form a multinucleated syncytium connected by cytoplasmic cables, and the calcitic skeleton is formed within these cables. Our primary concern is with the cellular and molecular mechanisms that support the formation of the mineralized spicules. The import of calcium into the PMCs results in appearance of intracellular vesicles containing precipitated calcium, which is neither very stable nor birefringent, and could be amorphous. The precipitated calcium is vectorially secreted into an extracellular space. This space is almost completely enclosed by cytoplasmic strands, and the mineral is encased in an extracellular matrix. Proteins destined for the extracellular matrix, and for inclusion in the spicule, are present in the Golgi membranes and in small intracellular vesicles. These vesicles apparently deliver the matrix proteins to the growing spicule. Our current view is that the matrix molecules are much more than a passive armature, but are actively involved in precipitation, secretion, and organization of the mineral phase.

A Combination Therapy of JO-I and Chemotherapy in Ovarian Cancer Models

DTIC Science & Technology

2013-10-01

which consists of a 3PAR storage backend and is sharing data via a highly available NetApp storage gateway and 2 high throughput commodity storage...Environment is configured as self- service Enterprise cloud and currently hosts more than 700 virtual machines. The network infrastructure consists of...technology infrastructure and information system applications designed to integrate, automate, and standardize operations. These systems fuse state of

NASA Icing Remote Sensing System Comparisons From AIRS II

NASA Technical Reports Server (NTRS)

Reehorst, Andrew L.; Brinker, David J.; Ratvasky, Thomas P.

2005-01-01

NASA has an on-going activity to develop remote sensing technologies for the detection and measurement of icing conditions aloft. A multiple instrument approach is the current emphasis of this activity. Utilizing radar, radiometry, and lidar, a region of supercooled liquid is identified. If the liquid water content (LWC) is sufficiently high, then the region of supercooled liquid cloud is flagged as being an aviation hazard. The instruments utilized for the current effort are an X-band vertical staring radar, a radiometer that measures twelve frequencies between 22 and 59 GHz, and a lidar ceilometer. The radar data determine cloud boundaries, the radiometer determines the sub-freezing temperature heights and total liquid water content, and the ceilometer refines the lower cloud boundary. Data is post-processed with a LabVIEW program with a resultant supercooled LWC profile and aircraft hazard identification. Individual remotely sensed measurements gathered during the 2003-2004 Alliance Icing Research Study (AIRS II) were compared to aircraft in-situ measurements. Comparisons between the remote sensing system s fused icing product and in-situ measurements from the research aircraft are reviewed here. While there are areas where improvement can be made, the cases examined indicate that the fused sensor remote sensing technique appears to be a valid approach.

Total Internal Reflection Ultrasonic Sensor for Detection of Subsurface Flaws: Research into Underlying Physics

DTIC Science & Technology

2014-11-24

layere, which was a thin plate bonded to a solid block of fused quartz. The plate was also made of fused quartz so the entire “assembly” may be... thin plate and a block of fused quartz. Residues of the lacquer Quartz plate Metal strip Epoxy layer Block of quartz Fig. 2.4.4. Specimen...depth therefore it was made as a combination of two pieces of fused quartz, a block and a thin plate , and a foreign inclusion between them. The plate was

Fluorine-Based DRIE of Fused Silica

NASA Technical Reports Server (NTRS)

Yee, Karl; Shcheglov, Kirill; Li, Jian; Choi, Daniel

2007-01-01

A process of deep reactive-ion etching (DRIE) using a fluorine-based gas mixture enhanced by induction-coupled plasma (ICP) has been demonstrated to be effective in forming high-aspect-ratio three-dimensional patterns in fused silica. The patterns are defined in part by an etch mask in the form of a thick, high-quality aluminum film. The process was developed to satisfy a need to fabricate high-aspect-ratio fused-silica resonators for vibratory microgyroscopes, and could be used to satisfy similar requirements for fabricating other fused-silica components.

Fused Silica and Other Transparent Window Materials

NASA Technical Reports Server (NTRS)

Salem, Jon

2016-01-01

Several transparent ceramics, such as spinel and AlONs are now being produced in sufficient large areas to be used in space craft window applications. The work horse transparent material for space missions from Apollo to the International Space Station has been fused silica due in part to its low coefficient of expansion and optical quality. Despite its successful use, fused silica exhibits anomalies in its crack growth behavior, depending on environmental preconditioning and surface damage. This presentation will compare recent optical ceramics to fused silica and discuss sources of variation in slow crack growth behavior.

Three-dimensional printing of transparent fused silica glass

NASA Astrophysics Data System (ADS)

Kotz, Frederik; Arnold, Karl; Bauer, Werner; Schild, Dieter; Keller, Nico; Sachsenheimer, Kai; Nargang, Tobias M.; Richter, Christiane; Helmer, Dorothea; Rapp, Bastian E.

2017-04-01

Glass is one of the most important high-performance materials used for scientific research, in industry and in society, mainly owing to its unmatched optical transparency, outstanding mechanical, chemical and thermal resistance as well as its thermal and electrical insulating properties. However, glasses and especially high-purity glasses such as fused silica glass are notoriously difficult to shape, requiring high-temperature melting and casting processes for macroscopic objects or hazardous chemicals for microscopic features. These drawbacks have made glasses inaccessible to modern manufacturing technologies such as three-dimensional printing (3D printing). Using a casting nanocomposite, here we create transparent fused silica glass components using stereolithography 3D printers at resolutions of a few tens of micrometres. The process uses a photocurable silica nanocomposite that is 3D printed and converted to high-quality fused silica glass via heat treatment. The printed fused silica glass is non-porous, with the optical transparency of commercial fused silica glass, and has a smooth surface with a roughness of a few nanometres. By doping with metal salts, coloured glasses can be created. This work widens the choice of materials for 3D printing, enabling the creation of arbitrary macro- and microstructures in fused silica glass for many applications in both industry and academia.

Joint image registration and fusion method with a gradient strength regularization

NASA Astrophysics Data System (ADS)

Lidong, Huang; Wei, Zhao; Jun, Wang

2015-05-01

Image registration is an essential process for image fusion, and fusion performance can be used to evaluate registration accuracy. We propose a maximum likelihood (ML) approach to joint image registration and fusion instead of treating them as two independent processes in the conventional way. To improve the visual quality of a fused image, a gradient strength (GS) regularization is introduced in the cost function of ML. The GS of the fused image is controllable by setting the target GS value in the regularization term. This is useful because a larger target GS brings a clearer fused image and a smaller target GS makes the fused image smoother and thus restrains noise. Hence, the subjective quality of the fused image can be improved whether the source images are polluted by noise or not. We can obtain the fused image and registration parameters successively by minimizing the cost function using an iterative optimization method. Experimental results show that our method is effective with transformation, rotation, and scale parameters in the range of [-2.0, 2.0] pixel, [-1.1 deg, 1.1 deg], and [0.95, 1.05], respectively, and variances of noise smaller than 300. It also demonstrated that our method yields a more visual pleasing fused image and higher registration accuracy compared with a state-of-the-art algorithm.

Fusion Bead Procedure for Nuclear Forensics Employing Synthetic Enstatite to Dissolve Uraniferous and Other Challenging Materials Prior to Laser Ablation Inductively Coupled Plasma Mass Spectrometry.

PubMed

Reading, David G; Croudace, Ian W; Warwick, Phillip E

2017-06-06

There is an increasing demand for rapid and effective analytical tools to support nuclear forensic investigations of seized or suspect materials. Some methods are simply adapted from other scientific disciplines and can effectively be used to rapidly prepare complex materials for subsequent analysis. A novel sample fusion method is developed, tested, and validated to produce homogeneous, flux-free glass beads of geochemical reference materials (GRMs), uranium ores, and uranium ore concentrates (UOC) prior to the analysis of 14 rare earth elements (REE) via laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). The novelty of the procedure is the production of glass beads using 9 parts high purity synthetic enstatite (MgSiO 3 ) as the glass former with 1 part of sample (sample mass ∼1.5 mg). The beads are rapidly prepared (∼10 min overall time) by fusing the blended mixture on an iridium strip resistance heater in an argon-purged chamber. Many elements can be measured in the glass bead, but the rare earth group in particular is a valuable series in nuclear forensic studies and is well-determined using LA-ICP-MS. The REE data obtained from the GRMs, presented as chondrite normalized patterns, are in very good agreement with consensus patterns. The UOCs have comparable patterns to solution ICP-MS methods and published data. The attractions of the current development are its conservation of sample, speed of preparation, and suitability for microbeam analysis, all of which are favorable for nuclear forensics practitioners and geochemists requiring REE patterns from scarce or valuable samples.

Changes in composition and porosity occurring during the thermal degradation of wood and wood components

USGS Publications Warehouse

Rutherford, David W.; Wershaw, Robert L.; Cox, Larry G.

2005-01-01

Samples of pine and poplar wood, pine bark, and purified cellulose and lignin were charred at temperatures ranging from 250?C to 500?C for times ranging from 1 hour to 168 hours. Changes in composition were examined by Fourier Transform Infrared (FTIR) and 13C Nuclear Magnetic Resonance (NMR) spectrometry, mass loss, and elemental composition (carbon, hydrogen, and oxygen) of the char. Structural changes were examined by changes in porosity as measured by nitrogen gas adsorption. 13C NMR spectrometry, mass loss, and elemental composition were combined to estimate the mass of aromatic and aliphatic carbon remaining in the char. Mass loss and elemental composition were combined to estimate the chemical composition of material lost for various time intervals of heating. These analyses showed that aliphatic components in the test materials were either lost or converted to aromatic carbon early in the charring process. Nitrogen adsorption showed that no porosity develops for any of the test materials with heating at 250?C, even though substantial loss of material and changes in composition occurred. Porosity development coincided with the loss of aromatic carbon, indicating that micropores were developing within a fused-ring matrix.

Flexibility in the mouse middle ear: A finite element study of the frequency response

NASA Astrophysics Data System (ADS)

Gottlieb, Peter; Puria, Sunil

2018-05-01

The mammalian middle ear is comprised of three distinct ossicles, connected by joints, and suspended in an air-filled cavity. In most mammals, the ossicular joints are mobile synovial joints, which introduce flexibility into the ossicular chain. In some smaller rodents, however, these joints are less mobile, and in the mouse in particular, the malleus is additionally characterized by a large, thin plate known as the transversal lamina, which connects the manubrium to the incus-malleus joint (IMJ). We hypothesize that this feature acts as a functional joint, maintaining the benefits of a flexible ossicular chain despite a less-mobile IMJ, and tested this hypothesis with a finite element model of the mouse middle ear. The results showed that while fusing the ossicular joints had a negligible effect on sound transmission, stiffening the ossicular bone significantly reduced sound transmission, implying that bone flexibility plays a critical role in the normal function of the mouse middle ear.

Tannins and terpenoids as major precursors of Suwannee River fulvic acid

USGS Publications Warehouse

Leenheer, Jerry A.; Rostad, Colleen E.

2004-01-01

Suwannee River fulvic acid (SRFA) was fractionated into 7 fractions by normal-phase chromatography on silica gel followed by reverse-phase fractionation on XAD-8 resin that produced 18 subfractions. Selected major subfractions were characterized by 13C-nuclear magnetic resonance (NMR), infrared spectrometry, and elemental analyses. 13C-NMR spectra of the subfractions were more indicative of precursor structures than unfractionated SRFA, and gave spectral profiles that indicated SRFA mass was about equally split between tannin precursors and terpenoid precursors. Lignin precursors were minor components. Synthesis of 13C-NMR data with elemental data for subfractions derived from both tannin and terpenoid precursors revealed high ring contents and low numbers of carbon per rings which is indicative of fused ring structures that are extensively substituted with carboxyl and methyl groups. These results ruled out extended chain structures for SRFA. This information is useful for determining sources and properties of fulvic acid in drinking water supplies as tannins are more reactive with chlorine to produce undesirable disinfection by-products than are terpenoids.

The relationship of the lunar regolith less than 10 micrometer fraction and agglutinates. I - A model for agglutinate formation and some indirect supportive evidence

NASA Technical Reports Server (NTRS)

Papike, J. J.; Simon, S. B.; White, C.; Laul, J. C.

1982-01-01

The first part of a study of the 'less than 10 micrometer' soil fraction and agglutinates is concerned with the chemical systematics of the considered fraction of lunar soils, taking into account a model for agglutinate formation based on the fusion of the finest fraction (FFF). Attention is given to some evidence which supports the FFF model. The evidence is based on some indirect approaches to an estimation of the composition of the fused soil component. It is found that the 'less than 10 micrometer' soil fraction from all Apollo sites except Apollo 16 (which can be explained) is more feldspathic and enriched in incompatible elements (e.g., K and Th) than the bulk soil. It is concluded that these systematics result from simple comminution in which feldspar breaks down to finer sizes than pyroxene and olivine and the fine-grained incompatible-element-enriched mesostasis concentrates in the 'less than 10 micrometer' soil fraction.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Casey, D. T.; Sayre, D. B.; Brune, C. R.

Stars are giant thermonuclear plasma furnaces that slowly fuse the lighter elements in the universe into heavier elements, releasing energy, and generating the pressure required to prevent collapse. To understand stars, we must rely on nuclear reaction rate data obtained, up to now, under conditions very different from those of stellar cores. Here we show thermonuclear measurements of the 2H(d, n) 3He and 3H(t,2n) 4He S-factors at a range of densities (1.2–16 g cm –3) and temperatures (2.1–5.4 keV) that allow us to test the conditions of the hydrogen-burning phase of main-sequence stars. The relevant conditions are created using inertial-confinementmore » fusion implosions at the National Ignition Facility. Here, our data agree within uncertainty with previous accelerator-based measurements and establish this approach for future experiments to measure other reactions and to test plasma-nuclear effects present in stellar interiors, such as plasma electron screening, directly in the environments where they occur.« less

Structure-guided statistical textural distinctiveness for salient region detection in natural images.

PubMed

Scharfenberger, Christian; Wong, Alexander; Clausi, David A

2015-01-01

We propose a simple yet effective structure-guided statistical textural distinctiveness approach to salient region detection. Our method uses a multilayer approach to analyze the structural and textural characteristics of natural images as important features for salient region detection from a scale point of view. To represent the structural characteristics, we abstract the image using structured image elements and extract rotational-invariant neighborhood-based textural representations to characterize each element by an individual texture pattern. We then learn a set of representative texture atoms for sparse texture modeling and construct a statistical textural distinctiveness matrix to determine the distinctiveness between all representative texture atom pairs in each layer. Finally, we determine saliency maps for each layer based on the occurrence probability of the texture atoms and their respective statistical textural distinctiveness and fuse them to compute a final saliency map. Experimental results using four public data sets and a variety of performance evaluation metrics show that our approach provides promising results when compared with existing salient region detection approaches.

Characterization of laser damage performance of fused silica using photothermal absorption technique

NASA Astrophysics Data System (ADS)

Wan, Wen; Shi, Feng; Dai, Yifan; Peng, Xiaoqiang

2017-06-01

The subsurface damage and metal impurities have been the main laser damage precursors of fused silica while subjected to high power laser irradiation. Light field enhancement and thermal absorption were used to explain the appearance of damage pits while the laser energy is far smaller than the energy that can reach the intrinsic threshold of fused silica. For fused silica optics manufactured by magnetorheological finishing or advanced mitigation process, no scratch-related damage site occurs can be found on the surface. In this work, we implemented a photothermal absorption technique based on thermal lens method to characterize the subsurface defects of fused silica optics. The pump beam is CW 532 nm wavelength laser. The probe beam is a He-Ne laser. They are collinear and focused through the same objective. When pump beam pass through the sample, optical absorption induces the local temperature rise. The lowest absorptance that we can detect is about the order of magnitude of 0.01 ppm. When pump beam pass through the sample, optical absorption induces the local temperature rise. The photothermal absorption value of fused silica samples range from 0.5 to 10 ppm. The damage densities of the samples were plotted. The damage threshold of samples at 8J/cm2 were gived to show laser damage performance of fused silica.The results show that there is a strong correlation between the thermal absorption and laser damage density. The photothermal absorption technique can be used to predict and evaluate the laser damage performance of fused silica optics.

Fused Bead Analysis of Diogenite Meteorites

NASA Technical Reports Server (NTRS)

Mittlefehldt, D.W.; Beck, B.W.; McSween, H.Y.; Lee, C.T. A.

2009-01-01

Bulk rock chemistry is an essential dataset in meteoritics and planetary science [1]. A common method used to obtain the bulk chemistry of meteorites is ICP-MS. While the accuracy, precision and low detection limits of this process are advantageous [2], the sample size used for analysis (approx.70 mg) can be a problem in a field where small and finite samples are the norm. Fused bead analysis is another bulk rock analytical technique that has been used in meteoritics [3]. This technique involves forming a glass bead from 10 mg of sample and measuring its chemistry using a defocused beam on a microprobe. Though the ICP-MS has lower detection limits than the microprobe, the fused bead method destroys a much smaller sample of the meteorite. Fused bead analysis was initially designed for samples with near-eutectic compositions and low viscosities. Melts generated of this type homogenize at relatively low temperatures and produce primary melts near the sample s bulk composition [3]. The application of fused bead analysis to samples with noneutectic melt compositions has not been validated. The purpose of this study is to test if fused bead analysis can accurately determine the bulk rock chemistry of non-eutectic melt composition meteorites. To determine this, we conduct two examinations of the fused bead. First, we compare ICP-MS and fused bead results of the same samples using statistical analysis. Secondly, we inspect the beads for the presence of crystals and chemical heterogeneity. The presence of either of these would indicate incomplete melting and quenching of the bead.

Formation of broadband antireflective and superhydrophilic subwavelength structures on fused silica using one-step self-masking reactive ion etching

PubMed Central

Ye, Xin; Jiang, Xiaodong; Huang, Jin; Geng, Feng; Sun, Laixi; Zu, Xiaotao; Wu, Weidong; Zheng, Wanguo

2015-01-01

Fused silica subwavelength structures (SWSs) with an average period of ~100 nm were fabricated using an efficient approach based on one-step self-masking reactive ion etching. The subwavelength structures exhibited excellent broadband antireflection properties from the ultraviolet to near-infrared wavelength range. These properties are attributable to the graded refractive index for the transition from air to the fused silica substrate that is produced by the ideal nanocone subwavelength structures. The transmittance in the 400–700 nm range increased from approximately 93% for the polished fused silica to greater than 99% for the subwavelength structure layer on fused silica. Achieving broadband antireflection in the visible and near-infrared wavelength range by appropriate matching of the SWS heights on the front and back sides of the fused silica is a novel strategy. The measured antireflection properties are consistent with the results of theoretical analysis using a finite-difference time-domain (FDTD) method. This method is also applicable to diffraction grating fabrication. Moreover, the surface of the subwavelength structures exhibits significant superhydrophilic properties. PMID:26268896

Evaluation and sensitivity testing of a coupled Landsat-MODIS downscaling method for land surface temperature and vegetation indices in semi-arid regions

NASA Astrophysics Data System (ADS)

Kim, Jongyoun; Hogue, Terri S.

2012-01-01

The current study investigates a method to provide land surface parameters [i.e., land surface temperature (LST) and normalized difference vegetation index (NDVI)] at a high spatial (˜30 and 60 m) and temporal (daily and 8-day) resolution by combining advantages from Landsat and moderate-resolution imaging spectroradiometer (MODIS) satellites. We adopt a previously developed subtraction method that merges the spatial detail of higher-resolution imagery (Landsat) with the temporal change observed in coarser or moderate-resolution imagery (MODIS). Applying the temporal difference between MODIS images observed at two different dates to a higher-resolution Landsat image allows prediction of a combined or fused image (Landsat+MODIS) at a future date. Evaluation of the resultant merged products is undertaken within the Southeastern Arizona region where data is available from a range of flux tower sites. The Landsat+MODIS fused products capture the raw Landsat values and also reflect the MODIS temporal variation. The predicted Landsat+MODIS LST improves mean absolute error around 5°C at the more heterogeneous sites compared to the original satellite products. The fused Landsat+MODIS NDVI product also shows good correlation to ground-based data and is relatively consistent except during the acute (monsoon) growing season. The sensitivity of the fused product relative to temporal gaps in Landsat data appears to be more affected by uncertainty associated with regional precipitation and green-up, than the length of the gap associated with Landsat viewing, suggesting the potential to use a minimal number of original Landsat images during relatively stable land surface and climate conditions. Our extensive validation yields insight on the ability of the proposed method to integrate multiscale platforms and the potential for reducing costs associated with high-resolution satellite systems (e.g., SPOT, QuickBird, IKONOS).

Heparin-binding peptide as a novel affinity tag for purification of recombinant proteins.

PubMed

Morris, Jacqueline; Jayanthi, Srinivas; Langston, Rebekah; Daily, Anna; Kight, Alicia; McNabb, David S; Henry, Ralph; Kumar, Thallapuranam Krishnaswamy Suresh

2016-10-01

Purification of recombinant proteins constitutes a significant part of the downstream processing in biopharmaceutical industries. Major costs involved in the production of bio-therapeutics mainly depend on the number of purification steps used during the downstream process. Affinity chromatography is a widely used method for the purification of recombinant proteins expressed in different expression host platforms. Recombinant protein purification is achieved by fusing appropriate affinity tags to either N- or C- terminus of the target recombinant proteins. Currently available protein/peptide affinity tags have proved quite useful in the purification of recombinant proteins. However, these affinity tags suffer from specific limitations in their use under different conditions of purification. In this study, we have designed a novel 34-amino acid heparin-binding affinity tag (HB-tag) for the purification of recombinant proteins expressed in Escherichia coli (E. coli) cells. HB-tag fused recombinant proteins were overexpressed in E. coli in high yields. A one-step heparin-Sepharose-based affinity chromatography protocol was developed to purify HB-fused recombinant proteins to homogeneity using a simple sodium chloride step gradient elution. The HB-tag has also been shown to facilitate the purification of target recombinant proteins from their 8 M urea denatured state(s). The HB-tag has been demonstrated to be successfully released from the fusion protein by an appropriate protease treatment to obtain the recombinant target protein(s) in high yields. Results of the two-dimensional NMR spectroscopy experiments indicate that the purified recombinant target protein(s) exist in the native conformation. Polyclonal antibodies raised against the HB-peptide sequence, exhibited high binding specificity and sensitivity to the HB-fused recombinant proteins (∼10 ng) in different crude cell extracts obtained from diverse expression hosts. In our opinion, the HB-tag provides a cost-effective, rapid, and reliable avenue for the purification of recombinant proteins in heterologous hosts. Copyright © 2016 Elsevier Inc. All rights reserved.

Visualization of aging-associated chromatin alterations with an engineered TALE system

PubMed Central

Ren, Ruotong; Deng, Liping; Xue, Yanhong; Suzuki, Keiichiro; Zhang, Weiqi; Yu, Yang; Wu, Jun; Sun, Liang; Gong, Xiaojun; Luan, Huiqin; Yang, Fan; Ju, Zhenyu; Ren, Xiaoqing; Wang, Si; Tang, Hong; Geng, Lingling; Zhang, Weizhou; Li, Jian; Qiao, Jie; Xu, Tao; Qu, Jing; Liu, Guang-Hui

2017-01-01

Visualization of specific genomic loci in live cells is a prerequisite for the investigation of dynamic changes in chromatin architecture during diverse biological processes, such as cellular aging. However, current precision genomic imaging methods are hampered by the lack of fluorescent probes with high specificity and signal-to-noise contrast. We find that conventional transcription activator-like effectors (TALEs) tend to form protein aggregates, thereby compromising their performance in imaging applications. Through screening, we found that fusing thioredoxin with TALEs prevented aggregate formation, unlocking the full power of TALE-based genomic imaging. Using thioredoxin-fused TALEs (TTALEs), we achieved high-quality imaging at various genomic loci and observed aging-associated (epi) genomic alterations at telomeres and centromeres in human and mouse premature aging models. Importantly, we identified attrition of ribosomal DNA repeats as a molecular marker for human aging. Our study establishes a simple and robust imaging method for precisely monitoring chromatin dynamics in vitro and in vivo. PMID:28139645

Fused Deposition Modeling 3D Printing for (Bio)analytical Device Fabrication: Procedures, Materials, and Applications

PubMed Central

2017-01-01

In this work, the use of fused deposition modeling (FDM) in a (bio)analytical/lab-on-a-chip research laboratory is described. First, the specifications of this 3D printing method that are important for the fabrication of (micro)devices were characterized for a benchtop FDM 3D printer. These include resolution, surface roughness, leakage, transparency, material deformation, and the possibilities for integration of other materials. Next, the autofluorescence, solvent compatibility, and biocompatibility of 12 representative FDM materials were tested and evaluated. Finally, we demonstrate the feasibility of FDM in a number of important applications. In particular, we consider the fabrication of fluidic channels, masters for polymer replication, and tools for the production of paper microfluidic devices. This work thus provides a guideline for (i) the use of FDM technology by addressing its possibilities and current limitations, (ii) material selection for FDM, based on solvent compatibility and biocompatibility, and (iii) application of FDM technology to (bio)analytical research by demonstrating a broad range of illustrative examples. PMID:28628294

One Stage Conversion of an Infected Fused Knee to Total Knee Replacement - A Surgical Challenge

PubMed Central

Ravikumar, Mukartihal; Kendoff, Daniel; Citak, Mustafa; Luck, Stefan; Gehrke, Thorsten; Zahar, Akos

2013-01-01

Background and Purpose: Two-stage revision arthroplasty is a common technique for the treatment of infected total knee replacement. Few reports have addressed the conversion of a fused knee into a total knee replacement. However, there is no case reported of converting an infected fused knee into a hinge knee using a one-stage procedure. Methods: We report on a 51-year old male patient with an infected fused knee after multiple surgeries. Results and Interpretation: A one-stage conversion of septic fused knee into total knee arthroplasty by a rotational hinge prosthesis was performed. The case highlights that with profound preoperative assessment, meticulous surgical technique, combined antibiotic treatment and the right implant, one-stage revision in a surgical challenge may have a role as a treatment option with good functional outcome. PMID:23526706

Military efforts in nanosensors, 3D printing, and imaging detection

NASA Astrophysics Data System (ADS)

Edwards, Eugene; Booth, Janice C.; Roberts, J. Keith; Brantley, Christina L.; Crutcher, Sihon H.; Whitley, Michael; Kranz, Michael; Seif, Mohamed; Ruffin, Paul

2017-04-01

A team of researchers and support organizations, affiliated with the Army Aviation and Missile Research, Development, and Engineering Center (AMRDEC), has initiated multidiscipline efforts to develop nano-based structures and components for advanced weaponry, aviation, and autonomous air/ground systems applications. The main objective of this research is to exploit unique phenomena for the development of novel technology to enhance warfighter capabilities and produce precision weaponry. The key technology areas that the authors are exploring include nano-based sensors, analysis of 3D printing constituents, and nano-based components for imaging detection. By integrating nano-based devices, structures, and materials into weaponry, the Army can revolutionize existing (and future) weaponry systems by significantly reducing the size, weight, and cost. The major research thrust areas include the development of carbon nanotube sensors to detect rocket motor off-gassing; the application of current methodologies to assess materials used for 3D printing; and the assessment of components to improve imaging seekers. The status of current activities, associated with these key areas and their implementation into AMRDEC's research, is outlined in this paper. Section #2 outlines output data, graphs, and overall evaluations of carbon nanotube sensors placed on a 16 element chip and exposed to various environmental conditions. Section #3 summarizes the experimental results of testing various materials and resulting components that are supplementary to additive manufacturing/fused deposition modeling (FDM). Section #4 recapitulates a preliminary assessment of the optical and electromechanical components of seekers in an effort to propose components and materials that can work more effectively.

Quantitative diagnosis and prognosis framework for concrete degradation due to alkali-silica reaction

NASA Astrophysics Data System (ADS)

Mahadevan, Sankaran; Neal, Kyle; Nath, Paromita; Bao, Yanqing; Cai, Guowei; Orme, Peter; Adams, Douglas; Agarwal, Vivek

2017-02-01

This research is seeking to develop a probabilistic framework for health diagnosis and prognosis of aging concrete structures in nuclear power plants that are subjected to physical, chemical, environment, and mechanical degradation. The proposed framework consists of four elements: monitoring, data analytics, uncertainty quantification, and prognosis. The current work focuses on degradation caused by ASR (alkali-silica reaction). Controlled concrete specimens with reactive aggregate are prepared to develop accelerated ASR degradation. Different monitoring techniques — infrared thermography, digital image correlation (DIC), mechanical deformation measurements, nonlinear impact resonance acoustic spectroscopy (NIRAS), and vibro-acoustic modulation (VAM) — are studied for ASR diagnosis of the specimens. Both DIC and mechanical measurements record the specimen deformation caused by ASR gel expansion. Thermography is used to compare the thermal response of pristine and damaged concrete specimens and generate a 2-D map of the damage (i.e., ASR gel and cracked area), thus facilitating localization and quantification of damage. NIRAS and VAM are two separate vibration-based techniques that detect nonlinear changes in dynamic properties caused by the damage. The diagnosis results from multiple techniques are then fused using a Bayesian network, which also helps to quantify the uncertainty in the diagnosis. Prognosis of ASR degradation is then performed based on the current state of degradation obtained from diagnosis, by using a coupled thermo-hydro-mechanical-chemical (THMC) model for ASR degradation. This comprehensive approach of monitoring, data analytics, and uncertainty-quantified diagnosis and prognosis will facilitate the development of a quantitative, risk informed framework that will support continuous assessment and risk management of structural health and performance.

Involvement of Ethylene in Stress-Induced Expression of the TLC1.1 Retrotransposon from Lycopersicon chilense Dun.1[w

PubMed Central

Tapia, Gerardo; Verdugo, Isabel; Yañez, Mónica; Ahumada, Iván; Theoduloz, Cristina; Cordero, Cecilia; Poblete, Fernando; González, Enrique; Ruiz-Lara, Simón

2005-01-01

The TLC1 family is one of the four families of long terminal repeat (LTR) retrotransposons identified in the genome of Lycopersicon chilense. Here, we show that this family of retroelements is transcriptionally active and its expression is induced in response to diverse stress conditions such as wounding, protoplast preparation, and high salt concentrations. Several stress-associated signaling molecules, including ethylene, methyl jasmonate, salicylic acid, and 2,4-dichlorophenoxyacetic acid, are capable of inducing TLC1 family expression in vivo. A representative of this family, named TLC1.1, was isolated from a genomic library from L. chilense. Transient expression assays in leaf protoplasts and stably transformed tobacco (Nicotiana tabacum) plants demonstrate that the U3 domain of the 5′-LTR region of this element can drive stress-induced transcriptional activation of the β-glucuronidase reporter gene. Two 57-bp tandem repeated sequences are found in this region, including an 8-bp motif, ATTTCAAA, previously identified as an ethylene-responsive element box in the promoter region of ethylene-induced genes. Expression analysis of wild-type LTR and single and double ethylene-responsive element box mutants fused to the β-glucuronidase gene shows that these elements are required for ethylene-responsive gene expression in protoplasts and transgenic plants. We suggest that ethylene-dependent signaling is the main signaling pathway involved in the regulation of the expression of the TLC1.1 element from L. chilense. PMID:16040666

Highly planar diarylamine-fused porphyrins and their remarkably stable radical cations† †Electronic supplementary information (ESI) available. CCDC 1469154–1469160. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc02721k Click here for additional data file. Click here for additional data file.

PubMed Central

Fukui, Norihito; Cha, Wonhee; Shimizu, Daiki; Oh, Juwon

2017-01-01

Oxidative fusion reactions of meso-phenoxazino Ni(ii) porphyrin were found to be temperature dependent, giving rise to either a doubly phenylene-fused product at room temperature or a singly phenoxazine-fused product at 70 °C. The latter was further oxidized to a doubly phenoxazine-fused Ni(ii) porphyrin, which was subsequently converted to the corresponding free base porphyrin and Zn(ii) porphyrin. Compared to previously reported diphenylamine-fused porphyrins that displayed a molecular twist, doubly phenoxazine-fused porphyrins exhibited distinctly different properties owing to their highly planar structures, such as larger fluorescence quantum yields, formation of an offset face-to-face dimer both in solution and the solid state, and the generation of a mixed-valence π-radical cation dimer upon electrochemical oxidation. One-electron oxidation of the phenoxazine-fused Ni(ii) porphyrin with Magic Blue gave the corresponding radical cation, which was certainly stable and could be isolated by separation over a silica gel column but slowly chlorinated at the reactive β-positions in the solid state. This finding led to us to examine β,β′-dichlorinated phenoxazine-fused and diphenylamine-fused Ni(ii) porphyrins, which, upon treatment with Magic Blue, provided remarkably stable radical cations to an unprecedented level. It is actually possible to purify these radical cations by silica gel chromatography, and they can be stored for over 6 months without any sign of deterioration. Moreover, they exhibited no degradation even after the CH2Cl2 solution was washed with water. However, subtle structural differences (planar versus partly twisted) led to different crystal packing structures and solid-state magnetic properties. PMID:28451165

Human adipose tissue-derived stem cells exhibit proliferation potential and spontaneous rhythmic contraction after fusion with neonatal rat cardiomyocytes.

PubMed

Metzele, Roxana; Alt, Christopher; Bai, Xiaowen; Yan, Yasheng; Zhang, Zhi; Pan, Zhizhong; Coleman, Michael; Vykoukal, Jody; Song, Yao-Hua; Alt, Eckhard

2011-03-01

Various types of stem cells have been shown to have beneficial effects on cardiac function. It is still debated whether fusion of injected stem cells with local resident cardiomyocytes is one of the mechanisms. To better understand the role of fusion in stem cell-based myocardial regeneration, the present study was designed to investigate the fate of human adipose tissue-derived stem cells (hASCs) fused with neonatal rat cardiomyocytes in vitro. hASCs labeled with the green fluorescent probe Vybrant DiO were cocultured with neonatal rat cardiomyocytes labeled with the red fluorescent probe Vybrant DiI and then treated with fusion-inducing hemagglutinating virus of Japan (HVJ). Cells that incorporated both red and green fluorescent signals were considered to be hASCs that had fused with rat cardiomyocytes. Fusion efficiency was 19.86 ± 4.84% at 5 d after treatment with HVJ. Most fused cells displayed cardiomyocyte-like morphology and exhibited spontaneous rhythmic contraction. Both immunofluorescence staining and lentiviral vector labeling showed that fused cells contained separate rat cardiomyocyte and hASC nuclei. Immunofluorescence staining assays demonstrated that human nuclei in fused cells still expressed the proliferation marker Ki67. In addition, hASCs fused with rat cardiomyocytes were positive for troponin I. Whole-cell voltage-clamp analysis demonstrated action potentials in beating fused cells. RT-PCR analysis using rat- or human-specific myosin heavy chain primers revealed that the myosin heavy-chain expression in fused cells was derived from rat cardiomyocytes. Real-time PCR identified expression of human troponin T in fused cells and the presence of rat cardiomyocytes induced a cardiomyogenic protein expression of troponin T in human ASCs. This study illustrates that hASCs exhibit both stem cell (proliferation) and cardiomyocyte properties (action potential and spontaneous rhythmic beating) after fusion with rat cardiomyocytes, supporting the theory that fusion, even if artificially induced in our study, could indeed be a mechanism for cardiomyocyte renewal in the heart.

[Color stability of porcelain-fused-to-titanium restorations after repeated firings].

PubMed

Wu, Xiao-min; Zhou, Zheng

2004-08-01

To study the effect of repeated firings on color of porcelain-fused-to-titanium restorations. Twenty standard porcelain-fused-to-titanium specimens were made with Dentsply DETREY TiBond C3 and Dentaurum rematitan Til. Then they were fired 1, 2, 4, 7, and 10 times. Color measurement was done after each firing. Most of the color parameters had no significant difference after firing except for a* and Hab. All the color difference among groups were smaller than 1.0 (deltaE < 1.0). Repeated firings will not affect the color stability of porcelain-fused-to-titanium restorations.

Tetrafluorobenzo-fused BODIPY: a platform for regioselective synthesis of BODIPY dye derivatives.

PubMed

Savoldelli, Andrea; Meng, Qianli; Paolesse, Roberto; Fronczek, Frank R; Smith, Kevin Malcolm; Vicente, M Graça Henriques

2018-05-18

A novel route for the synthesis of unsymmetrical benzo-fused BODIPYs is reported using 4,5,6,7-tetrafluoroisoindole as a precursor. The reactivity of the asymmetric 3,5-dibromo benzo-fused BODIPY was investigated under nucleophilic substitution and Pd(0)-catalyzed cross-coupling reaction conditions. In addition to the 3,5-bromines, one α-fluoro group on the benzo-fused ring can also be functionalized, and an unusual homocoupling with formation of a bisBODIPY was observed. This new class of fluorinated BODIPYs could find various applications in medicine and materials.

Radioactive source localization in urban environments with sensor networks and the Internet of Things

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sullivan, Clair J.

The use of radiation detectors as an element in the so-called “Internet of Things” has recently become viable with the available of low-cost, mobile radiation sensors capable of streaming geo-referenced data. New methods for fusing the data from multiple sensors on such a network is presented. The traditional simple and ordinary Kriging methods present a challenge for such a network since the assumption of a constant mean is not valid in this application. In conclusion, a variety of Kalman filters are introduced in an attempt to solve the problem associated with this variable and unknown mean. Results are presented onmore » a deployed sensor network.« less

Spectral Analysis of PG 1034+001, the Exciting Star of Hewett 1

NASA Technical Reports Server (NTRS)

Kruk, J. W.; Mahsereci, M.; Ringat, E.; Rauch, T.; Werner, K.

2011-01-01

PG 1034+001 is an extremely hot, helium-rich DO-type star that excites the planetary nebula Hewett 1 and large parts of the surrounding interstellar medium. We present preliminary results of an ongoing spectral analysis by means of non-LTE model atmospheres that consider most elements from hydrogen to nickel. This analysis is based on high-resolution ultraviolet (FUSE, IUE) and optical (VLT/UVES, KECK) data. The results are compared with those of PG 1034+001's spectroscopic twin, the DO star PG 0038+ 199. Keywords. stars: abundances, stars: AGB and post-AGB, stars: atmospheres, stars: evolution, stars: individual (PG 1034+001, PG 0038+ 199), planetary nebulae: individual (Hewett 1)

Radioactive source localization in urban environments with sensor networks and the Internet of Things

DOE PAGES

Sullivan, Clair J.

2016-01-01

The use of radiation detectors as an element in the so-called “Internet of Things” has recently become viable with the available of low-cost, mobile radiation sensors capable of streaming geo-referenced data. New methods for fusing the data from multiple sensors on such a network is presented. The traditional simple and ordinary Kriging methods present a challenge for such a network since the assumption of a constant mean is not valid in this application. In conclusion, a variety of Kalman filters are introduced in an attempt to solve the problem associated with this variable and unknown mean. Results are presented onmore » a deployed sensor network.« less

Fault Analysis in Solar Photovoltaic Arrays

NASA Astrophysics Data System (ADS)

Zhao, Ye

Fault analysis in solar photovoltaic (PV) arrays is a fundamental task to increase reliability, efficiency and safety in PV systems. Conventional fault protection methods usually add fuses or circuit breakers in series with PV components. But these protection devices are only able to clear faults and isolate faulty circuits if they carry a large fault current. However, this research shows that faults in PV arrays may not be cleared by fuses under some fault scenarios, due to the current-limiting nature and non-linear output characteristics of PV arrays. First, this thesis introduces new simulation and analytic models that are suitable for fault analysis in PV arrays. Based on the simulation environment, this thesis studies a variety of typical faults in PV arrays, such as ground faults, line-line faults, and mismatch faults. The effect of a maximum power point tracker on fault current is discussed and shown to, at times, prevent the fault current protection devices to trip. A small-scale experimental PV benchmark system has been developed in Northeastern University to further validate the simulation conclusions. Additionally, this thesis examines two types of unique faults found in a PV array that have not been studied in the literature. One is a fault that occurs under low irradiance condition. The other is a fault evolution in a PV array during night-to-day transition. Our simulation and experimental results show that overcurrent protection devices are unable to clear the fault under "low irradiance" and "night-to-day transition". However, the overcurrent protection devices may work properly when the same PV fault occurs in daylight. As a result, a fault under "low irradiance" and "night-to-day transition" might be hidden in the PV array and become a potential hazard for system efficiency and reliability.

Structural characterization and regulatory element analysis of the heart isoform of cytochrome c oxidase VIa

NASA Technical Reports Server (NTRS)

Wan, B.; Moreadith, R. W.; Blomqvist, C. G. (Principal Investigator)

1995-01-01

In order to investigate the mechanism(s) governing the striated muscle-specific expression of cytochrome c oxidase VIaH we have characterized the murine gene and analyzed its transcriptional regulatory elements in skeletal myogenic cell lines. The gene is single copy, spans 689 base pairs (bp), and is comprised of three exons. The 5'-ends of transcripts from the gene are heterogeneous, but the most abundant transcript includes a 5'-untranslated region of 30 nucleotides. When fused to the luciferase reporter gene, the 3.5-kilobase 5'-flanking region of the gene directed the expression of the heterologous protein selectively in differentiated Sol8 cells and transgenic mice, recapitulating the pattern of expression of the endogenous gene. Deletion analysis identified a 300-bp fragment sufficient to direct the myotube-specific expression of luciferase in Sol8 cells. The region lacks an apparent TATA element, and sequence motifs predicted to bind NRF-1, NRF-2, ox-box, or PPAR factors known to regulate other nuclear genes encoding mitochondrial proteins are not evident. Mutational analysis, however, identified two cis-elements necessary for the high level expression of the reporter protein: a MEF2 consensus element at -90 to -81 bp and an E-box element at -147 to -142 bp. Additional E-box motifs at closely located positions were mutated without loss of transcriptional activity. The dependence of transcriptional activation of cytochrome c oxidase VIaH on cis-elements similar to those found in contractile protein genes suggests that the striated muscle-specific expression is coregulated by mechanisms that control the lineage-specific expression of several contractile and cytosolic proteins.

Current measurement apparatus

DOEpatents

Umans, Stephen D.

2008-11-11

Apparatus and methods are provided for a system for measurement of a current in a conductor such that the conductor current may be momentarily directed to a current measurement element in order to maintain proper current without significantly increasing an amount of power dissipation attributable to the current measurement element or adding resistance to assist in current measurement. The apparatus and methods described herein are useful in superconducting circuits where it is necessary to monitor current carried by the superconducting elements while minimizing the effects of power dissipation attributable to the current measurement element.

31 CFR 100.12 - Exchange of fused and mixed coins.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Exchange of fused and mixed coins... OF PAPER CURRENCY AND COIN Exchange of Coin § 100.12 Exchange of fused and mixed coins. (a... the majority of which are readily and clearly identifiable as U.S. coins. (2) Mixed coins are U.S...

A hybrid color mapping approach to fusing MODIS and Landsat images for forward prediction

USDA-ARS?s Scientific Manuscript database

We present a new, simple, and efficient approach to fusing MODIS and Landsat images. It is well known that MODIS images have high temporal resolution and low spatial resolution whereas Landsat images are just the opposite. Similar to earlier approaches, our goal is to fuse MODIS and Landsat images t...

Dicobalt hexacarbonyl complexes of alkynyl imines in a sequential Staudinger/Pauson-Khand process. A route to new fused tricyclic beta-lactams.

PubMed

Olier, Clarisse; Azzi, Nadia; Gil, Gérard; Gastaldi, Stéphane; Bertrand, Michèle P

2008-11-07

Dicobalt hexacarbonyl complexes of alkynyl imines were allowed to react with ketenes via Staudinger reaction. Sequential [2 + 2] cycloaddition/Pauson-Khand reaction led to structurally new fused-tricyclic beta-lactams and fused-azabicyclic cyclopentenones. Chemoselectivity, scope, and limitation of the process were investigated.

L-shaped right-to-left crossed-fused renal ectopia with left dysplastic ureter.

PubMed

Song, Wei; Yang, Jinrui; Zhu, Liang; Liu, Longfei

2012-01-01

Crossed-fused renal ectopia is a relatively rare congenital malformation. Herein, we report a case of L-shaped right- to-left crossed-fused renal ectopia with a left dysplastic ureter in a 5-year-old girl. She underwent a left nephrectomy and the postoperative course was uneventful. Copyright © 2011 S. Karger AG, Basel.

Investigation of a High Voltage, High Frequency Power Conditioning System for Use with Flux Compression Generators

DTIC Science & Technology

2007-06-01

missouri.edu Abstract The University of Missouri-Columbia is developing a compact pulsed power system to condition the high current signal from a...flux compression generator (FCG) to the high voltage, high frequency signal required for many pulsed power applications. The system consists of a...non-magnetic core, spiral-wound transformer, series exploding wire fuse, and an oscillating mesoband source. The flux compression generator is being

US EPA 2012 Air Quality Fused Surface for the Conterminous U.S. Map Service

EPA Pesticide Factsheets

This web service contains a polygon layer that depicts fused air quality predictions for 2012 for census tracts in the conterminous United States. Fused air quality predictions (for ozone and PM2.5) are modeled using a Bayesian space-time downscaling fusion model approach described in a series of three published journal papers: 1) (Berrocal, V., Gelfand, A. E. and Holland, D. M. (2012). Space-time fusion under error in computer model output: an application to modeling air quality. Biometrics 68, 837-848; 2) Berrocal, V., Gelfand, A. E. and Holland, D. M. (2010). A bivariate space-time downscaler under space and time misalignment. The Annals of Applied Statistics 4, 1942-1975; and 3) Berrocal, V., Gelfand, A. E., and Holland, D. M. (2010). A spatio-temporal downscaler for output from numerical models. J. of Agricultural, Biological,and Environmental Statistics 15, 176-197) is used to provide daily, predictive PM2.5 (daily average) and O3 (daily 8-hr maximum) surfaces for 2012. Summer (O3) and annual (PM2.5) means calculated and published. The downscaling fusion model uses both air quality monitoring data from the National Air Monitoring Stations/State and Local Air Monitoring Stations (NAMS/SLAMS) and numerical output from the Models-3/Community Multiscale Air Quality (CMAQ). Currently, predictions at the US census tract centroid locations within the 12 km CMAQ domain are archived. Predictions at the CMAQ grid cell centroids, or any desired set of locations co

Resource-efficient generation of linear cluster states by linear optics with postselection

DOE PAGES

Uskov, D. B.; Alsing, P. M.; Fanto, M. L.; ...

2015-01-30

Here we report on theoretical research in photonic cluster-state computing. Finding optimal schemes of generating non-classical photonic states is of critical importance for this field as physically implementable photon-photon entangling operations are currently limited to measurement-assisted stochastic transformations. A critical parameter for assessing the efficiency of such transformations is the success probability of a desired measurement outcome. At present there are several experimental groups that are capable of generating multi-photon cluster states carrying more than eight qubits. Separate photonic qubits or small clusters can be fused into a single cluster state by a probabilistic optical CZ gate conditioned on simultaneousmore » detection of all photons with 1/9 success probability for each gate. This design mechanically follows the original theoretical scheme of cluster state generation proposed more than a decade ago by Raussendorf, Browne, and Briegel. The optimality of the destructive CZ gate in application to linear optical cluster state generation has not been analyzed previously. Our results reveal that this method is far from the optimal one. Employing numerical optimization we have identified that the maximal success probability of fusing n unentangled dual-rail optical qubits into a linear cluster state is equal to 1/2 n-1; an m-tuple of photonic Bell pair states, commonly generated via spontaneous parametric down-conversion, can be fused into a single cluster with the maximal success probability of 1/4 m-1.« less

Process for manufacturing hollow fused-silica insulator cylinder

DOEpatents

Sampayan, Stephen E.; Krogh, Michael L.; Davis, Steven C.; Decker, Derek E.; Rosenblum, Ben Z.; Sanders, David M.; Elizondo-Decanini, Juan M.

2001-01-01

A method for building hollow insulator cylinders that can have each end closed off with a high voltage electrode to contain a vacuum. A series of fused-silica round flat plates are fabricated with a large central hole and equal inside and outside diameters. The thickness of each is related to the electron orbit diameter of electrons that escape the material surface, loop, and return back. Electrons in such electron orbits can support avalanche mechanisms that result in surface flashover. For example, the thickness of each of the fused-silica round flat plates is about 0.5 millimeter. In general, the thinner the better. Metal, such as gold, is deposited onto each top and bottom surface of the fused-silica round flat plates using chemical vapor deposition (CVD). Eutectic metals can also be used with one alloy constituent on the top and the other on the bottom. The CVD, or a separate diffusion step, can be used to defuse the deposited metal deep into each fused-silica round flat plate. The conductive layer may also be applied by ion implantation or gas diffusion into the surface. The resulting structure may then be fused together into an insulator stack. The coated plates are aligned and then stacked, head-to-toe. Such stack is heated and pressed together enough to cause the metal interfaces to fuse, e.g., by welding, brazing or eutectic bonding. Such fusing is preferably complete enough to maintain a vacuum within the inner core of the assembled structure. A hollow cylinder structure results that can be used as a core liner in a dielectric wall accelerator and as a vacuum envelope for a vacuum tube device where the voltage gradients exceed 150 kV/cm.

New false color mapping for image fusion

NASA Astrophysics Data System (ADS)

Toet, Alexander; Walraven, Jan

1996-03-01

A pixel-based color-mapping algorithm is presented that produces a fused false color rendering of two gray-level images representing different sensor modalities. The resulting images have a higher information content than each of the original images and retain sensor-specific image information. The unique component of each image modality is enhanced in the resulting fused color image representation. First, the common component of the two original input images is determined. Second, the common component is subtracted from the original images to obtain the unique component of each image. Third, the unique component of each image modality is subtracted from the image of the other modality. This step serves to enhance the representation of sensor-specific details in the final fused result. Finally, a fused color image is produced by displaying the images resulting from the last step through, respectively, the red and green channels of a color display. The method is applied to fuse thermal and visual images. The results show that the color mapping enhances the visibility of certain details and preserves the specificity of the sensor information. The fused images also have a fairly natural appearance. The fusion scheme involves only operations on corresponding pixels. The resolution of a fused image is therefore directly related to the resolution of the input images. Before fusing, the contrast of the images can be enhanced and their noise can be reduced by standard image- processing techniques. The color mapping algorithm is computationally simple. This implies that the investigated approaches can eventually be applied in real time and that the hardware needed is not too complicated or too voluminous (an important consideration when it has to fit in an airplane, for instance).

Regulatory elements involved in constitutive and phorbol ester-inducible expression of the plasminogen activator inhibitor type 2 gene promoter.

PubMed Central

Cousin, E; Medcalf, R L; Bergonzelli, G E; Kruithof, E K

1991-01-01

Gene transcription rates and mRNA levels of plasminogen activator inhibitor type 2 (PAI-2) are markedly induced by the tumor promoting agent phorbol 12-myristate 13-acetate (PMA) in human HT1080 fibrosarcoma cells. To identify promoter elements required for basal-, and phorbol ester-inducible expression, deletion mutants of the PAI-1 promoter fused to the chloramphenicol acetyl transferase (CAT) reporter gene, were transiently expressed in HT1080 cells. Constitutive CAT activity was expressed from constructs containing more than 215 bp of promoter sequence, whereas deletion to position -91 bp abolished CAT gene expression. Treatment of transfected cells with PMA resulted in a three- to ten-fold increase in CAT expression from all constructs except from the construct shortened to position -91. DNAse1 protection analysis of the promoter region between -215 and the transcription initiation site revealed numerous protected regions, including two AP1-like binding sites (AP1a and AP1b) and one CRE-like element. Site-directed mutagenesis of the AP1a site or of the CRE-like site resulted in the loss of basal CAT activity and abolished the PMA effect, whereas mutagenesis of AP1b only partially inhibited basal and PMA-mediated expression. Our results suggest that the PAI-2 promoter contains at least two elements required for basal gene transcription and PMA-mediated induction. Images PMID:1650454

Determination of the absolute configurations at stereogenic centers in the presence of axial chirality.

PubMed

Polavarapu, Prasad L; Jeirath, Neha; Kurtán, Tibor; Pescitelli, Gennaro; Krohn, Karsten

2009-01-01

Cephalochromin, a homodimeric naphthpyranone natural product, contains both axial chirality due to the hindered rotation along the biaryl axis and central chirality due to the C-2, C-2' stereogenic centers of the fused pyranone ring. For determining the absolute configurations (ACs) of central chirality elements, different chiroptical spectroscopic methods, namely vibrational circular dichroism (VCD), electronic circular dichroism (ECD), and optical rotation (OR), have been used. From these experimental data, in conjunction with corresponding quantum chemical predictions at B3LYP/6-311G* level, it is found that the ECD spectra of cephalochromin are dominated by its axial chirality and are not suitable to distinguish the (aS,2S,2'S) and (aS,2R,2'R) diastereomers and hence to determine the ACs of the central chirality elements. OR signs also did not distinguish the (aS,2S,2'S) and (aS,2R,2'R) diastereomers. On other hand, VCD spectrum of cephalochromin exhibited separate spectral features attributable to axial chirality and stereogenic centers, thereby allowing the determination of both types of chirality elements. This is the first investigation demonstrating that, because of vibrations specific to the studied stereogenic centers, VCD spectroscopy can be used to simultaneously determine the ACs of axial and central chirality elements whenever other chiroptical methods (ECD and OR) fail to report on them. (c) 2009 Wiley-Liss, Inc.

Synthesis of partially and fully fused polyaromatics by annulative chlorophenylene dimerization.

PubMed

Koga, Yoshito; Kaneda, Takeshi; Saito, Yutaro; Murakami, Kei; Itami, Kenichiro

2018-01-26

Since the discovery by Ullmann and Bielecki in 1901, reductive dimerization (or homocoupling) of aryl halides has been extensively exploited for the generation of a range of biaryl-based functional molecules. In contrast to the single-point connection in these products, edge-sharing fused aromatic systems have not generally been accessible from simple aryl halides via annulation cascades. Here we report a single-step synthesis of fused aromatics with a triphenylene core by the palladium-catalyzed annulative dimerization of structurally and functionally diverse chlorophenylenes through double carbon-hydrogen bond activation. The partially fused polyaromatics can be transformed into fully fused, small graphene nanoribbons, which are otherwise difficult to synthesize. This simple, yet powerful, method allows access to functional π-systems of interest in optoelectronics research. Copyright © 2018, The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Infrared and Visible Image Fusion Based on Different Constraints in the Non-Subsampled Shearlet Transform Domain.

PubMed

Huang, Yan; Bi, Duyan; Wu, Dongpeng

2018-04-11

There are many artificial parameters when fuse infrared and visible images, to overcome the lack of detail in the fusion image because of the artifacts, a novel fusion algorithm for infrared and visible images that is based on different constraints in non-subsampled shearlet transform (NSST) domain is proposed. There are high bands and low bands of images that are decomposed by the NSST. After analyzing the characters of the bands, fusing the high level bands by the gradient constraint, the fused image can obtain more details; fusing the low bands by the constraint of saliency in the images, the targets are more salient. Before the inverse NSST, the Nash equilibrium is used to update the coefficient. The fused images and the quantitative results demonstrate that our method is more effective in reserving details and highlighting the targets when compared with other state-of-the-art methods.

Quantification of residual stress from photonic signatures of fused silica

NASA Astrophysics Data System (ADS)

Cramer, K. Elliott; Hayward, Maurice; Yost, William T.

2014-02-01

A commercially available grey-field polariscope (GFP) instrument for photoelastic examination is used to assess impact damage inflicted upon the outer-most pane of Space Shuttle windows made from fused silica. A method and apparatus for calibration of the stress-optic coefficient using four-point bending is discussed. The results are validated on known material (acrylic) and are found to agree with literature values to within 6%. The calibration procedure is then applied to fused-silica specimens and the stress-optic coefficient is determined to be 2.43 ± 0.54 × 10-12 Pa-1. Fused silica specimens containing impacts artificially made at NASA's Hypervelocity Impact Technology Facility (HIT-F), to simulate damage typical during space flight, are examined. The damage sites are cored from fused silica window carcasses and examined with the GFP. The calibrated GFP measurements of residual stress patterns surrounding the damage sites are presented.

Infrared and Visible Image Fusion Based on Different Constraints in the Non-Subsampled Shearlet Transform Domain

PubMed Central

Huang, Yan; Bi, Duyan; Wu, Dongpeng

2018-01-01

There are many artificial parameters when fuse infrared and visible images, to overcome the lack of detail in the fusion image because of the artifacts, a novel fusion algorithm for infrared and visible images that is based on different constraints in non-subsampled shearlet transform (NSST) domain is proposed. There are high bands and low bands of images that are decomposed by the NSST. After analyzing the characters of the bands, fusing the high level bands by the gradient constraint, the fused image can obtain more details; fusing the low bands by the constraint of saliency in the images, the targets are more salient. Before the inverse NSST, the Nash equilibrium is used to update the coefficient. The fused images and the quantitative results demonstrate that our method is more effective in reserving details and highlighting the targets when compared with other state-of-the-art methods. PMID:29641505

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doualle, T.; Gallais, L., E-mail: laurent.gallais@fresnel.fr; Cormont, P.

We investigate the effect of different heat treatments on the laser-induced damage probabilities of fused silica samples. Isothermal annealing in a furnace is applied, with different temperatures in the range 700–1100 °C and 12 h annealing time, to super-polished fused silica samples. The surface flatness and laser damage probabilities at 3 ns, 351 nm are measured before and after the different annealing procedures. We have found a significant improvement of the initial laser damage probabilities of the silica surface after annealing at 1050 °C for 12 h. A similar study has been conducted on CO{sub 2} laser-processed sites on the surface of the samples. Before andmore » after annealing, we have studied the morphology of the sites, the evolution of residual stress, and the laser-induced damage threshold measured at 351 nm, 3 ns. In this case, we observe that the laser damage resistance of the laser created craters can reach the damage level of the bare fused silica surface after the annealing process, with a complete stress relieve. The obtained results are then compared to the case of local annealing process by CO{sub 2} laser irradiation during 1 s, and we found similar improvements in both cases. The different results obtained in the study are compared to numerical simulations made with a thermo-mechanical model based on finite-element method that allows the simulation of the isothermal or the local annealing process, the evolution of stress and fictive temperature. The simulation results were found to be very consistent with experimental observations for the stresses evolution after annealing and estimation of the heat affected area during laser-processing based on the density dependence with fictive temperature. Following this work, the temperature for local annealing should reach 1330–1470 °C for an optimized reduction of damage probability and be below the threshold for material removal, whereas furnace annealing should be kept below the annealing point to avoid sample deformation.« less

Laser-induced damage and fracture in fused silica vacuum windows

NASA Astrophysics Data System (ADS)

Campbell, John H.; Hurst, Patricia A.; Heggins, Dwight D.; Steele, William A.; Bumpas, Stanley E.

1997-05-01

Laser induced damage, that initiates catastrophic fracture, has been observed in large, fused silica lenses that also serve as vacuum barriers in high-fluence positions on the Nova and Beamlet lasers. In nearly all cases damage occurs on the vacuum side of the lens. The damage can lead to catastrophic crack growth if the flaw size exceeds the critical flaw size for SiO2. If the elastic stored energy in the lens in high enough, the lens will fracture into many pieces resulting in an implosion. The consequences of such an implosion can be severe, particularly for large vacuum systems. Three parameters control the degree of fracture in the vacuum barrier window: (1) the elastic stored energy, (2) the ratio of the window thickness to flaw depth and (3) secondary crack propagation. Fracture experiments have ben carried our on 15-cm diameter fused silica windows that contain surface flaws caused by laser damage. The results of these experiments, combined with data from window failures on Beamlet and Nova have been sued to develop design criteria for a 'fail-safe' lens. Specifically the window must be made thick enough such that the peak tensile stress is less than 500 psi and the corresponding ratio of the thickness to critical flaw size is less than 6. Under these conditions a properly mounted window, upon failure, will break into only tow pieces and will not implode. One caveat to these design criteria is that the air leak through the window before secondary crack growth occurs. Finite element stress calculations of a window before and immediately following fracture into two pieces show that the elastic stored energy is redistributed if the fragments 'lock' in place and thereby bridge the opening. In such cases, the peak stresses at the flaw site can increase leading to further crack growth.

75 FR 64633 - Airworthiness Directives; The Boeing Company Model 767-200, -300, and -300F Series Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-20

... repetitive inspections for fatigue cracking and corrosion of the upper link fuse pin of the nacelle struts... fatigue cracking or corrosion of the upper link fuse pin, which could result in failure of the fuse pin... Model 767-200, -300, and - 300F series airplanes. That AD requires repetitive inspections for fatigue...

The size prediction of potential inclusions embedded in the sub-surface of fused silica by damage morphology

NASA Astrophysics Data System (ADS)

Gao, Xiang; Qiu, Rong; Wang, Kunpeng; Zhang, Jiangmei; Zhou, Guorui; Yao, Ke; Jiang, Yong; Zhou, Qiang

2017-04-01

A model for predicting the size ranges of different potential inclusions initiating damage on the surface of fused silica has been presented. This accounts for the heating of nanometric inclusions whose absorptivity is described based on Mie Theory. The depth profile of impurities has been measured by ICP-OES. By the measured temporal pulse profile on the surface of fused silica, the temperature and thermal stress has been calculated. Furthermore, considering the limit conditions of temperature and thermal stress strength for different damage morphologies, the size range of potential inclusions for fused silica is discussed.

Thermodynamic perturbation theory for fused sphere hard chain fluids using nonadditive interactions

NASA Astrophysics Data System (ADS)

Abu-Sharkh, Basel F.; Sunaidi, Abdallah; Hamad, Esam Z.

2004-03-01

A model is developed for the equation of state of fused chains based on Wertheim thermodynamic perturbation theory and nonadditive size interactions. The model also assumes that the structure (represented by the radial distribution function) of the fused chain fluid is the same as that of the touching hard sphere chain fluid. The model is completely based on spherical additive and nonadditive size interactions. The model has the advantage of offering good agreement with simulation data while at the same time being independent of fitted parameters. The model is most accurate for short chains, small values of Δ (slightly fused spheres) and at intermediate (liquidlike) densities.

[Study on content of nickel in saliva released from the nickel-chromium and the nickel-chromium-titanium porcelain alloy].

PubMed

Wang, Wen-Jie; Zhang, Tai-Qiang; Wei, Hong

2010-02-01

The purpose of the study was to investigate the content of nickel (Ni) ion in patients' saliva after wearing the porcelain-fused-to nickel-chromium (Ni-Cr) crown or the porcelain-fused-to nickel-chromium-titanium(Ni-Cr-Ti) crown. 50 patients who had one molar or premolar needed repairing were selected and divided into two groups randomly. Patients in one group were fabricated with porcelain-fused-to Ni-Cr crown and the patients in the other group were fabricated with porcelain-fused-to Ni-Cr-Ti crown. Collect the patients' saliva before wearing, 1 week, 3 months, and 6 months after wearing. The content of Ni ion in saliva was detected by inductively coupled plasma mass spectrometry (ICP-MS). The content of Ni ion in both groups increased at the first week, and go back after 6 months. There were no significant differences before wearing, 1 week, 3 months, and 6 months after wearing. There were no significant differences between the two groups. Wearing the porcelain-fused-to Ni-Cr crown or the porcelain-fused-to Ni-Cr-Ti crown has no significant influence on the content of Ni ion in saliva.

Recycling potential for low voltage and high voltage high rupturing capacity fuse links.

PubMed

Psomopoulos, Constantinos S; Barkas, Dimitrios A; Kaminaris, Stavros D; Ioannidis, George C; Karagiannopoulos, Panagiotis

2017-12-01

Low voltage and high voltage high-rupturing-capacity fuse links are used in LV and HV installations respectively, protecting mainly the LV and HV electricity distribution and transportation networks. The Waste Electrical and Electronic Equipment Directive (2002/96/EC) for "Waste of electrical and electronic equipment" is the main related legislation and as it concerns electrical and electronic equipment, it includes electric fuses. Although, the fuse links consist of recyclable materials, only small scale actions have been implemented for their recycling around Europe. This work presents the possibilities for material recovery from this specialized industrial waste for which there are only limited volume data. Furthermore, in order to present the huge possibilities and environmental benefits, it presents the potential for recycling of HRC fuses used by the Public Power Corporation of Greece, which is the major consumer for the country, but one of the smallest ones in Europe and globally, emphasizing in this way in the issue. According to the obtained results, fuse recycling could contribute to the effort for minimize the impacts on the environment through materials recovery and reduction of the wastes' volume disposed of in landfills. Copyright © 2017 Elsevier Ltd. All rights reserved.

An underlap field-effect transistor for electrical detection of influenza

NASA Astrophysics Data System (ADS)

Lee, Kwang-Won; Choi, Sung-Jin; Ahn, Jae-Hyuk; Moon, Dong-Il; Park, Tae Jung; Lee, Sang Yup; Choi, Yang-Kyu

2010-01-01

An underlap channel-embedded field-effect transistor (FET) is proposed for label-free biomolecule detection. Specifically, silica binding protein fused with avian influenza (AI) surface antigen and avian influenza antibody (anti-AI) were designed as a receptor molecule and a target material, respectively. The drain current was significantly decreased after the binding of negatively charged anti-AI on the underlap channel. A set of control experiments supports that only the biomolecules on the underlap channel effectively modulate the drain current. With the merits of a simple fabrication process, complementary metal-oxide-semiconductor compatibility, and enhanced sensitivity, the underlap FET could be a promising candidate for a chip-based biosensor.

Quantitative real-time monitoring of multi-elements in airborne particulates by direct introduction into an inductively coupled plasma mass spectrometer

NASA Astrophysics Data System (ADS)

Suzuki, Yoshinari; Sato, Hikaru; Hiyoshi, Katsuhiro; Furuta, Naoki

2012-10-01

A new calibration system for real-time determination of trace elements in airborne particulates was developed. Airborne particulates were directly introduced into an inductively coupled plasma mass spectrometer, and the concentrations of 15 trace elements were determined by means of an external calibration method. External standard solutions were nebulized by an ultrasonic nebulizer (USN) coupled with a desolvation system, and the resulting aerosol was introduced into the plasma. The efficiency of sample introduction via the USN was calculated by two methods: (1) the introduction of a Cr standard solution via the USN was compared with introduction of a Cr(CO)6 standard gas via a standard gas generator and (2) the aerosol generated by the USN was trapped on filters and then analyzed. The Cr introduction efficiencies obtained by the two methods were the same, and the introduction efficiencies of the other elements were equal to the introduction efficiency of Cr. Our results indicated that our calibration method for introduction efficiency worked well for the 15 elements (Ti, V, Cr, Mn, Co, Ni, Cu, Zn, As, Mo, Sn, Sb, Ba, Tl and Pb). The real-time data and the filter-collection data agreed well for elements with low-melting oxides (V, Co, As, Mo, Sb, Tl, and Pb). In contrast, the real-time data were smaller than the filter-collection data for elements with high-melting oxides (Ti, Cr, Mn, Ni, Cu, Zn, Sn, and Ba). This result implies that the oxides of these 8 elements were not completely fused, vaporized, atomized, and ionized in the initial radiation zone of the inductively coupled plasma. However, quantitative real-time monitoring can be realized after correction for the element recoveries which can be calculated from the ratio of real-time data/filter-collection data.

Evolution of Hsp70 Gene Expression: A Role for Changes in AT-Richness within Promoters

PubMed Central

Ma, Ronghui; Zhang, Bo; Kang, Le

2011-01-01

In disparate organisms adaptation to thermal stress has been linked to changes in the expression of genes encoding heat-shock proteins (Hsp). The underlying genetics, however, remain elusive. We show here that two AT-rich sequence elements in the promoter region of the hsp70 gene of the fly Liriomyza sativae that are absent in the congeneric species, Liriomyza huidobrensis, have marked cis-regulatory consequences. We studied the cis-regulatory consequences of these elements (called ATRS1 and ATRS2) by measuring the constitutive and heat-shock-induced luciferase luminescence that they drive in cells transfected with constructs carrying them modified, deleted, or intact, in the hsp70 promoter fused to the luciferase gene. The elements affected expression level markedly and in different ways: Deleting ATRS1 augmented both the constitutive and the heat-shock-induced luminescence, suggesting that this element represses transcription. Interestingly, replacing the element with random sequences of the same length and A+T content delivered the wild-type luminescence pattern, proving that the element's high A+T content is crucial for its effects. Deleting ATRS2 decreased luminescence dramatically and almost abolished heat-shock inducibility and so did replacing the element with random sequences matching the element's length and A+T content, suggesting that ATRS2's effects on transcription and heat-shock inducibility involve a common mechanism requiring at least in part the element's specific primary structure. Finally, constitutive and heat-shock luminescence were reduced strongly when two putative binding sites for the Zeste transcription factor identified within ATRS2 were altered through site-directed mutagenesis, and the heat-shock-induced luminescence increased when Zeste was over-expressed, indicating that Zeste participates in the effects mapped to ATRS2 at least in part. AT-rich sequences are common in promoters and our results suggest that they should play important roles in regulatory evolution since they can affect expression markedly and constrain promoter DNA in at least two different ways. PMID:21655251

Spondylectomy and lateral lumbar interbody fusion for thoracolumbar kyphosis in an adult with achondroplasia

PubMed Central

Miyazaki, Masashi; Kanezaki, Shozo; Notani, Naoki; Ishihara, Toshinobu; Tsumura, Hiroshi

2017-01-01

Abstract Rationale: Fixed thoracolumbar kyphosis with spinal stenosis in adult patients with achondroplasia presents a challenging issue. We describe the first case in which spondylectomy and minimally invasive lateral access interbody arthrodesis were used for the treatment of fixed severe thoracolumbar kyphosis and lumbar spinal canal stenosis in an adult with achondroplasia. Patient concerns: A 61-year-old man with a history of achondroplastic dwarfism presented with low back pain and radiculopathy and neurogenic claudication. Diagnoses: Plain radiographs revealed a high-grade thoracolumbar kyphotic deformity with diffuse degenerative changes in the lumbar spine. The apex was located at L2, the local kyphotic angle from L1 to L3 was 105°, and the anterior area was fused from the L1 to L3 vertebrae. MRI revealed significant canal and lateral recess stenosis secondary to facet hypertrophy. Interventions: We planned a front-back correction of the anterior and posterior spinal elements. We first performed anterior release at the fused part from L1 to L3 and XLIF at L3/4 and L4/5. Next, the patient was placed in the prone position. Spondylectomy at the L2 vertebra and posterior fusion from T10 to L5 were performed. Postoperative radiographs revealed L1 to L3 kyphosis of 32°. Outcomes: No complications occurred during or after surgery. Postoperatively, the patient's low back pain and neurological claudication were resolved. No worsening of kyphosis was observed 24 months postoperatively. Lessons: Circumferential decompression of the spinal cord at the apical vertebral level and decompression of lumbar canal stenosis were necessary. Front-back correction of the anterior and posterior spinal elements via spondylectomy and lateral lumbar interbody fusion is a reasonable surgical option for thoracolumbar kyphosis and developmental canal stenosis in patients with achondroplasia. PMID:29245270

Optical performance of random anti-reflection structured surfaces (rARSS) on spherical lenses

NASA Astrophysics Data System (ADS)

Taylor, Courtney D.

Random anti-reflection structured surfaces (rARSS) have been reported to improve transmittance of optical-grade fused silica planar substrates to values greater than 99%. These textures are fabricated directly on the substrates using reactive-ion/inductively-coupled plasma etching (RIE/ICP) techniques, and often result in transmitted spectra with no measurable interference effects (fringes) for a wide range of wavelengths. The RIE/ICP processes used in the fabrication process to etch the rARSS is anisotropic and thus well suited for planar components. The improvement in spectral transmission has been found to be independent of optical incidence angles for values from 0° to +/-30°. Qualifying and quantifying the rARSS performance on curved substrates, such as convex lenses, is required to optimize the fabrication of the desired AR effect on optical-power elements. In this work, rARSS was fabricated on fused silica plano-convex (PCX) and plano-concave (PCV) lenses using a planar-substrate optimized RIE process to maximize optical transmission in the range from 500 to 1100 nm. An additional set of lenses were etched in a non-optimized ICP process to provide additional comparisons. Results are presented from optical transmission and beam propagation tests (optimized lenses only) of rARSS lenses for both TE and TM incident polarizations at a wavelength of 633 nm and over a 70° full field of view in both singlet and doublet configurations. These results suggest optimization of the fabrication process is not required, mainly due to the wide angle-of-incidence AR tolerance performance of the rARSS lenses. Non-optimized recipe lenses showed low transmission enhancement, and confirmed the need to optimized etch recipes prior to process transfer of PCX/PCV lenses. Beam propagation tests indicated no major beam degradation through the optimized lens elements. Scanning electron microscopy (SEM) images confirmed different structure between optimized and non-optimized samples. SEM images also indicated isotropically-oriented surface structures on both types of lenses.

Synthesis of pyrido[1,2-a]benzimidazoles and other fused imidazole derivatives with a bridgehead nitrogen atom

NASA Astrophysics Data System (ADS)

Begunov, Roman S.; Ryzvanovich, Galina A.

2013-01-01

Main methods for the synthesis of fused imidazole derivatives with a bridgehead nitrogen atom are systematically considered and summarized. The reaction mechanisms that underlie the methods for the synthesis of pyrido[1,2-a]benzimidazoles and related compounds are described. Biological properties and mechanisms of the biological activity of fused azaheterocycles are discussed. The bibliography includes 152 references.

Synthesis of pyridine-fused perylene imides with an amidine moiety for hydrogen bonding.

PubMed

Ito, Satoru; Hiroto, Satoru; Shinokubo, Hiroshi

2013-06-21

Pyridine-fused perylene tetracarboxylic acid bisimides (PBIs) were synthesized via Suzuki-Miyaura coupling and acid condensation. The fused PBIs with electron-donating substituents exhibited an intramolecular charge transfer interaction. One of the N-alkyl substituents was selectively removed with BBr3 to create an amidine guest binding site. A hydrogen bonding interaction with pentafluorobenzoic acid changed the absorption spectra and enhanced fluorescence.