Comparison between fractionation and bioavailability of trace elements in rhizosphere and bulk soils.

PubMed

Wang, Zhongwen; Shan, Xiao-Quan; Zhang, Shuzhen

2002-03-01

Rhizosphere is a microbiosphere and has quite different chemical, physical and biological properties from bulk soils. A greenhouse experiment was performed to compare the difference of fractionation and bioavailability of trace elements Cr, Ni, Zn, Cu, Pb and Cd between rhizosphere soil and bulk soil. In the meantime, the influence of air-drying on the fractionation and bioavailability was also investigated by using wet soil sample as a control. Soils in a homemade rhizobox were divided into four zones: rhizosphere, near rhizosphere, near bulk soil and bulk soil zones, which was designated as S1, S2, S3 and S4. Elemental speciations were fractionated to water soluble, exchangeable and carbonate bound (B1), Fe-Mn oxide bound (B2), and organic and sulfide bound (B3) by a sequential extraction procedure. Speciation differences were observed for elements Cr, Ni, Zn, Cu, Pb and Cd between the rhizosphere and bulk soils, and between the air-dried and wet soils as well. The concentrations of all six heavy metals in fraction B1 followed the order of S2 > S3 > S1 > S4 and for B2, the order was S2 > S3 S4 > S1. For B3, the order was S1 > S3 S4 > S2, while for Cd the order was S2 > S3 approximately/= S4 > S1. The air-drying increased elemental concentration in fractions B1 and B2 by 20-50% and decreased in fraction B3 by about 20-100%. Correlation analysis also indicated that the bioavailability correlation coefficient of fraction B1 in rhizosphere wet soil to plants was better than that between either air-dried or nonrhizosphere soils. Therefore, application of rhizosphere wet soils should be recommended in the future study on the speciation analysis of trace elements in soils and bioavailability.

77 FR 76112 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-26

... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-68468; File No. SR-FINRA-2012-055] Self...-Element Continuing Education Program To Qualify To Engage in a Security Futures Business December 19, 2012. Pursuant to Section 19(b)(1) of the Securities Exchange Act of 1934 (``Act'')\\1\\ and Rule 19b-4 thereunder...

[Analysis of the mineral elements of Lactuca sativa under the condition of different spectral components].

PubMed

Chen, Xiao-Li; Guo, Wen-Zhong; Xue, Xu-Zhang; Wang, Li-Chun; Li, Liang; Chen, Fei

2013-08-01

Mineral elements absorption and content of Lactuca sativa under different spectral component conditions were studied by ICP-AES technology. The results showed that: (1) For Lactuca sativa, the average proportion for Ca : Mg : K : Na : P was 5.5 : 2.5 : 2.3 : 1.5 : 1.0, the average proportion for Fe : Mn : Zn : Cu : B was 25.9 : 5.9 : 2.8 : 1.1 : 1.0; (2) The absorptions for K, P, Ca, Mg and B are the largest under the LED treatment R/B = 1 : 2.75, red light from fluorescent lamps and LED can both promote the absorptions of Fe and Cu; (3)The LED treatments exhibiting relatively higher content of mineral elements are R/B = 1 : 2.75 and R/W = 1 : 1 while higher dry matter accumulations are R/B = 1 : 2.75 and B/W = 1 : 1.

The National Shipbuilding Research Program. 1989 Ship Production Symposium. Paper No. 3: Producibility in Ship Design

DTIC Science & Technology

1989-09-01

INNOVATION MARINE INDUSTRY STANDARDS WELDING INDUSTRIAL ENGINEERING EDUCATION AND TRAINING THE NATIONAL SHIPBUILDING RESEARCH PROGRAM September 1989 NSRP 0310...SEP 1989 2. REPORT TYPE 3. DATES COVERED 00-00-1989 to 00-00-1989 4. TITLE AND SUBTITLE The National Shipbuilding Research Program . 1989 Ship...Production Symposium, Paper No. 3: Producibility in Ship Design 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d

Hybridogenesis and a potential case of R2 non-LTR retrotransposon horizontal transmission in Bacillus stick insects (Insecta Phasmida).

PubMed

Scavariello, Claudia; Luchetti, Andrea; Martoni, Francesco; Bonandin, Livia; Mantovani, Barbara

2017-02-06

Horizontal transfer (HT) is an event in which the genetic material is transferred from one species to another, even if distantly related, and it has been demonstrated as a possible essential part of the lifecycle of transposable elements (TEs). However, previous studies on the non-LTR R2 retrotransposon, a metazoan-wide distributed element, indicated its vertical transmission since the Radiata-Bilateria split. Here we present the first possible instances of R2 HT in stick insects of the genus Bacillus (Phasmida). Six R2 elements were characterized in the strictly bisexual subspecies B. grandii grandii, B. grandii benazzii and B. grandii maretimi and in the obligatory parthenogenetic taxon B. atticus. These elements were compared with those previously retrieved in the facultative parthenogenetic species B. rossius. Phylogenetic inconsistencies between element and host taxa, and age versus divergence analyses agree and support at least two HT events. These HT events can be explained by taking into consideration the complex Bacillus reproductive biology, which includes also hybridogenesis, gynogenesis and androgenesis. Through these non-canonical reproductive modes, R2 elements may have been transferred between Bacillus genomes. Our data suggest, therefore, a possible role of hybridization for TEs survival and the consequent reshaping of involved genomes.

A qualitative study of the infant feeding beliefs and behaviours of mothers with low educational attainment.

PubMed

Russell, Catherine Georgina; Taki, Sarah; Azadi, Leva; Campbell, Karen J; Laws, Rachel; Elliott, Rosalind; Denney-Wilson, Elizabeth

2016-05-21

Infancy is an important period for the promotion of healthy eating, diet and weight. However little is known about how best to engage caregivers of infants in healthy eating programs. This is particularly true for caregivers, infants and children from socioeconomically disadvantaged backgrounds who experience greater rates of overweight and obesity yet are more challenging to reach in health programs. Behaviour change interventions targeting parent-infant feeding interactions are more likely to be effective if assumptions about what needs to change for the target behaviours to occur are identified. As such we explored the precursors of key obesity promoting infant feeding practices in mothers with low educational attainment. One-on-one semi-structured telephone interviews were developed around the Capability Opportunity Motivation Behaviour (COM-B) framework and applied to parental feeding practices associated with infant excess or healthy weight gain. The target behaviours and their competing alternatives were (a) initiating breastfeeding/formula feeding, (b) prolonging breastfeeding/replacing breast milk with formula, (c) best practice formula preparation/sub-optimal formula preparation, (d) delaying the introduction of solid foods until around six months of age/introducing solids earlier than four months of age, and (e) introducing healthy first foods/introducing unhealthy first foods, and (f) feeding to appetite/use of non-nutritive (i.e., feeding for reasons other than hunger) feeding. The participants' education level was used as the indicator of socioeconomic disadvantage. Two researchers independently undertook thematic analysis. Participants were 29 mothers of infants aged 2-11 months. The COM-B elements of Social and Environmental Opportunity, Psychological Capability, and Reflective Motivation were the key elements identified as determinants of a mother's likelihood to adopt the healthy target behaviours although the relative importance of each of the COM-B factors varied with each of the target feeding behaviours. Interventions targeting healthy infant feeding practices should be tailored to the unique factors that may influence mothers' various feeding practices, taking into account motivational and social influences.

32 CFR Appendix B to Part 80 - Procedures for Special Educational Programs (Including Related Services) for Preschool Children...

Code of Federal Regulations, 2012 CFR

2012-07-01

... Appendix B to Part 80 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL... IEP, provided that the Department of Defense, its constituent elements, and its personnel, are not... to an independent evaluation, but not at the expense of the Department of Defense or any DoD...

32 CFR Appendix B to Part 80 - Procedures for Special Educational Programs (Including Related Services) for Preschool Children...

Code of Federal Regulations, 2011 CFR

2011-07-01

... Appendix B to Part 80 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL... IEP, provided that the Department of Defense, its constituent elements, and its personnel, are not... to an independent evaluation, but not at the expense of the Department of Defense or any DoD...

32 CFR Appendix B to Part 80 - Procedures for Special Educational Programs (Including Related Services) for Preschool Children...

Code of Federal Regulations, 2014 CFR

2014-07-01

... Appendix B to Part 80 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL... IEP, provided that the Department of Defense, its constituent elements, and its personnel, are not... to an independent evaluation, but not at the expense of the Department of Defense or any DoD...

32 CFR Appendix B to Part 80 - Procedures for Special Educational Programs (Including Related Services) for Preschool Children...

Code of Federal Regulations, 2013 CFR

2013-07-01

... Appendix B to Part 80 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL... IEP, provided that the Department of Defense, its constituent elements, and its personnel, are not... to an independent evaluation, but not at the expense of the Department of Defense or any DoD...

Requirement for ErbB2/ErbB signaling in developing cartilage and bone.

PubMed

Fisher, Melanie C; Clinton, Gail M; Maihle, Nita J; Dealy, Caroline N

2007-08-01

During endochondral ossification, the skeletal elements of vertebrate limbs form and elongate via coordinated control of chondrocyte and osteoblast differentiation and proliferation. The role of signaling by the ErbB family of receptor tyrosine kinases, which consists of ErbB1 (epidermal growth factor receptor or EGFR), ErbB2, ErbB3 and ErbB4, has been little studied during cartilage and bone development. Signaling by the ErbB network generates a diverse array of cellular responses via formation of ErbB dimers activated by distinct ligands that produce distinct signal outputs. Herstatin is a soluble ErbB2 receptor that acts in a dominant negative fashion to inhibit ErbB signaling by binding to endogenous ErbB receptors, preventing functional dimer formation. Here, we examine the effects of Herstatin on limb skeletal element development in transgenic mice, achieved via Prx1 promoter-driven expression in limb cartilage and bone. The limb skeletal elements of Prx1-Herstatin embryos are shortened, and chondrocyte maturation and osteoblast differentiation are delayed. In addition, proliferation by chondrocytes and periosteal cells of Prx1-Herstatin limb skeletal elements is markedly reduced. Our study identifies requirements for ErbB signaling in the maintenance of chondrocyte and osteoblast proliferation involved in the timely progression of chondrocyte maturation and periosteal osteoblast differentiation.

Substitution of Nd with other rare earth elements in melt spun Nd{sub 2}Fe{sub 14}B magnets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, D. N.; Lau, D.; Chen, Z.

2016-05-15

This is a contemporary study of rapidly quenched Nd{sub 1.6}X{sub 0.4}Fe{sub 14}B magnetic materials (where X= Nd, Y, Ce, La, Pr, Gd and Ho). A 20% substitution of the Nd component from Nd{sub 2}Fe{sub 14}B can bring about some commercial advantage. However, there will be some compromise to the magnetic performance. Light rare earth elements are definitely more abundant (Y, Ce, La) than the heavier rare earth elements, but when they are included in RE{sub 2}Fe{sub 14}B magnets they tend to lower magnetic performance and thermal stability. Substituting heavy rare earth elements (Gd, Ho) for Nd in Nd{sub 2}Fe{sub 14}Bmore » improves the thermal stability of magnets but causes a loss in magnet remanence.« less

A.B.C. Prunes, U.F.O. News, and Politicks: Parody in Media Literacy Education

ERIC Educational Resources Information Center

Ohta, Ralph

2005-01-01

Parody is a form of imitation with the added elements of comedic twists, turns, and exaggerations. To create a parody of something, one has to understand it before beginning to alter it for humorous effect. Parodies are used by teachers of writing, music, and art as a method of educating and evaluating students' understanding of the styles of the…

36 CFR 230.35 - FLEP elements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false FLEP elements. 230.35 Section... FORESTRY ASSISTANCE Forest Land Enhancement Program § 230.35 FLEP elements. (a) States may use FLEP funds... through the following elements: (1) Development and implementation of educational programs; (2) Resource...

36 CFR 230.35 - FLEP elements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false FLEP elements. 230.35 Section... FORESTRY ASSISTANCE Forest Land Enhancement Program § 230.35 FLEP elements. (a) States may use FLEP funds... through the following elements: (1) Development and implementation of educational programs; (2) Resource...

36 CFR 230.35 - FLEP elements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false FLEP elements. 230.35 Section... FORESTRY ASSISTANCE Forest Land Enhancement Program § 230.35 FLEP elements. (a) States may use FLEP funds... through the following elements: (1) Development and implementation of educational programs; (2) Resource...

36 CFR 230.35 - FLEP elements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false FLEP elements. 230.35 Section... FORESTRY ASSISTANCE Forest Land Enhancement Program § 230.35 FLEP elements. (a) States may use FLEP funds... through the following elements: (1) Development and implementation of educational programs; (2) Resource...

36 CFR 230.35 - FLEP elements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false FLEP elements. 230.35 Section... FORESTRY ASSISTANCE Forest Land Enhancement Program § 230.35 FLEP elements. (a) States may use FLEP funds... through the following elements: (1) Development and implementation of educational programs; (2) Resource...

Educating for Innovation: Finding Balance in the Army’s Professional Military Education System

DTIC Science & Technology

2016-06-10

Faculty of the U.S. Army Command and General Staff College in partial fulfillment of the requirements for the degree MASTER OF MILITARY ART AND...Balance in the Army’s Professional Military Education System 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ...Paul N. de León, Major 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) U.S

Dimension-six matrix elements for meson mixing and lifetimes from sum rules

NASA Astrophysics Data System (ADS)

Kirk, M.; Lenz, A.; Rauh, T.

2017-12-01

The hadronic matrix elements of dimension-six Δ F = 0, 2 operators are crucial inputs for the theory predictions of mixing observables and lifetime ratios in the B and D system. We determine them using HQET sum rules for three-point correlators. The results of the required three-loop computation of the correlators and the one-loop computation of the QCD-HQET matching are given in analytic form. For mixing matrix elements we find very good agreement with recent lattice results and comparable theoretical uncertainties. For lifetime matrix elements we present the first ever determination in the D meson sector and the first determination of Δ B = 0 matrix elements with uncertainties under control — superseeding preliminary lattice studies stemming from 2001 and earlier. With our state-of-the-art determination of the bag parameters we predict: τ( B +)/ τ( B d 0 ) = 1.082 - 0.026 + 0.022 , τ( B s 0 )/ τ( B d 0 ) = 0.9994 ± 0.0025, τ( D +)/ τ( D 0) = 2. 7 - 0.8 + 0.7 and the mixing-observables in the B s and B d system, in good agreement with the most recent experimental averages.

Control of myogenesis by rodent SINE-containing lncRNAs

PubMed Central

Wang, Jiashi; Gong, Chenguang; Maquat, Lynne E.

2013-01-01

Staufen1-mediated mRNA decay (SMD) degrades mRNAs that harbor a Staufen1-binding site (SBS) in their 3′ untranslated regions (UTRs). Human SBSs can form by intermolecular base-pairing between a 3′ UTR Alu element and an Alu element within a long noncoding RNA (lncRNA) called a ½-sbsRNA. Since Alu elements are confined to primates, it was unclear how SMD occurs in rodents. Here we identify mouse mRNA 3′ UTRs and lncRNAs that contain a B1, B2, B4, or identifier (ID) element. We show that SMD occurs in mouse cells via mRNA–lncRNA base-pairing of partially complementary elements and that mouse ½-sbsRNA (m½-sbsRNA)-triggered SMD regulates C2C12 cell myogenesis. Our findings define new roles for lncRNAs as well as B and ID short interspersed elements (SINEs) in mice that undoubtedly influence many developmental and homeostatic pathways. PMID:23558772

Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction.

PubMed

Granzier, Henk L; Radke, Michael H; Peng, Jun; Westermann, Dirk; Nelson, O Lynne; Rost, Katharina; King, Nicholas M P; Yu, Qianli; Tschöpe, Carsten; McNabb, Mark; Larson, Douglas F; Labeit, Siegfried; Gotthardt, Michael

2009-09-11

The giant protein titin plays key roles in myofilament assembly and determines the passive mechanical properties of the sarcomere. The cardiac titin molecule has 2 mayor elastic elements, the N2B and the PEVK region. Both have been suggested to determine the elastic properties of the heart with loss of function data only available for the N2B region. The purpose of this study was to investigate the contribution of titin's proline-glutamate-valine-lysine (PEVK) region to biomechanics and growth of the heart. We removed a portion of the PEVK segment (exons 219 to 225; 282 aa) that corresponds to the PEVK element of N2B titin, the main cardiac titin isoform. Adult homozygous PEVK knockout (KO) mice developed diastolic dysfunction, as determined by pressure-volume loops, echocardiography, isolated heart experiments, and muscle mechanics. Immunoelectron microscopy revealed increased strain of the N2B element, a spring region retained in the PEVK-KO. Interestingly, the PEVK-KO mice had hypertrophied hearts with an induction of the hypertrophy and fetal gene response that includes upregulation of FHL proteins. This contrasts the cardiac atrophy phenotype with decreased FHL2 levels that result from the deletion of the N2B element. Titin's PEVK region contributes to the elastic properties of the cardiac ventricle. Our findings are consistent with a model in which strain of the N2B spring element and expression of FHL proteins trigger cardiac hypertrophy. These novel findings provide a molecular basis for the future differential therapy of isolated diastolic dysfunction versus more complex cardiomyopathies.

Transactivation of the Brassica napus napin promoter by ABI3 requires interaction of the conserved B2 and B3 domains of ABI3 with different cis-elements: B2 mediates activation through an ABRE, whereas B3 interacts with an RY/G-box.

PubMed

Ezcurra, I; Wycliffe, P; Nehlin, L; Ellerström, M; Rask, L

2000-10-01

The transcriptional activator ABI3 is a key regulator of gene expression during embryo maturation in crucifers. In monocots, the related VP1 protein regulates the Em promoter synergistically with abscisic acid (ABA). We identified cis-elements in the Brassica napus napin napA promoter mediating regulation by ABI3 and ABA, by analyzing substitution mutation constructs of napA in transgenic tobacco plantlets ectopically expressing ABI3. In transient analysis using particle bombardment of tobacco leaf sections, a tetramer of the distB ABRE (abscisic acid-responsive element) mediated transactivation by ABI3 and ABI3-dependent response to ABA, whereas a tetramer of the composite RY/G complex, containing RY repeats and a G-box, mediated only ABA-independent transactivation by ABI3. Deletion of the conserved B2 and B3 domains of ABI3 abolished transactivation of napA by ABI3. The two domains of ABI3 interact with different cis-elements: B2 is necessary for ABA-independent and ABA-dependent activations through the distB ABRE, whereas B3 interacts with the RY/G complex. Thus B2 mediates the interaction of ABI3 with the protein complex at the ABRE. The regulation of napA by ABI3 differs from Em regulation by VP1, in that the B3 domain of ABI3 is essential for the ABA-dependent regulation of napA.

The site-specific ribosomal insertion element type II of Bombyx mori (R2Bm) contains the coding sequence for a reverse transcriptase-like enzyme.

PubMed Central

Burke, W D; Calalang, C C; Eickbush, T H

1987-01-01

Two classes of DNA elements interrupt a fraction of the rRNA repeats of Bombyx mori. We have analyzed by genomic blotting and sequence analysis one class of these elements which we have named R2. These elements occupy approximately 9% of the rDNA units of B. mori and appear to be homologous to the type II rDNA insertions detected in Drosophila melanogaster. Approximately 25 copies of R2 exist within the B. mori genome, of which at least 20 are located at a precise location within otherwise typical rDNA units. Nucleotide sequence analysis has revealed that the 4.2-kilobase-pair R2 element has a single large open reading frame, occupying over 82% of the total length of the element. The central region of this 1,151-amino-acid open reading frame shows homology to the reverse transcriptase enzymes found in retroviruses and certain transposable elements. Amino acid homology of this region is highest to the mobile line 1 elements of mammals, followed by the mitochondrial type II introns of fungi, and the pol gene of retroviruses. Less homology exists with transposable elements of D. melanogaster and Saccharomyces cerevisiae. Two additional regions of sequence homology between L1 and R2 elements were also found outside the reverse transcriptase region. We suggest that the R2 elements are retrotransposons that are site specific in their insertion into the genome. Such mobility would enable these elements to occupy a small fraction of the rDNA units of B. mori despite their continual elimination from the rDNA locus by sequence turnover. Images PMID:2439905

Perspectives on Interagency Collaboration.

ERIC Educational Resources Information Center

Western States Technical Assistance Resource, Monmouth, OR.

Seven papers are presented from a 1982 conference on interagency collaboration in special education. Participants at the conference represented a variety of disciplines. B. McNulty and E. Soper cite 14 critical elements of successful interagency practice in chapter I, including communication, conflict resolution strategies, commitment to an…

Longitudinal Surveys of Australian Youth (LSAY) 2009 Cohort User Guide: Data Elements B1--Education (School and School Transition). Technical Paper 74B1

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2012

2012-01-01

This is a support document to the "Longitudinal Surveys of Australian Youth (LSAY) 2009 Cohort User Guide" report. Developed for users of LSAY, the user guide consolidates information about the LSAY 2009 cohort into one document. This support document provides school and school transition information for the guide. [For the main report,…

A Coaching Intervention to Promote Nutrition and Bone Health in Deployed Soldiers

DTIC Science & Technology

2015-03-13

to Promote Nutrition and Bone Health in Deployed Soldiers 5b. GRANT NUMBER HU0001-10-1-TS15 5c. PROGRAM ELEMENT NUMBER N/A 6. AUTHOR(S...Purpose: The purpose of this study was to determine if telehealth coaching is superior to one-time nutrition and fitness education regarding...leisure activities. All soldiers received one-time nutrition and fitness education prior to deployment; Telehealth Group received health-related

Response of basic structural elements and B-52 structural components to simulated nuclear overpressure. Volume II-program data (basic structural elements). Final report, 1 June 1977-30 September 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Syring, R.P.; Grubb, R.L.

1979-09-30

This document reports on the following: (1) experimental determination of the response of 16 basic structural elements and 7 B-52 components to simulated nuclear overpressure environments (utilizing Sandia Corporation's Thunderpipe Shock Tube), (2) analysis of these test specimens utilizing the NOVA-2 computer program, and (3) correlation of test and analysis results.

cis- and trans-acting elements of the estrogen-regulated vitellogenin gene B1 of Xenopus laevis.

PubMed

Wahli, W; Martinez, E; Corthésy, B; Cardinaux, J R

1989-01-01

Vitellogenin genes are expressed under strict estrogen control in the liver of female oviparous vertebrates. Gene transfer experiments using estrogen-responsive cells have shown that the 13 bp perfect palindromic element GGTCACTGTGACC found upstream of the Xenopus laevis vitellogenin gene A2 promoter mediates hormonal stimulation and thus, was called the estrogen-responsive element (ERE). In the Xenopus vitellogenin genes B1 and B2 there are two closely adjacent EREs with one or more base substitutions when compared to the consensus ERE GGTCANNNTGACC. On their own, these degenerated elements have only a low or no regulatory capacity at all but act together synergistically to form an estrogen-responsive unit (ERU) with the same strength as the perfect palindromic 13 bp element. Analysis of estrogen receptor binding to the gene B1 ERU revealed a cooperative interaction of receptor dimers to the two adjacent imperfect EREs which most likely explains the synergistic stimulation observed in vivo. Furthermore, a promoter activator element located between positions --113 and --42 of the gene B1 and functional in the human MCF-7 and the Xenopus B3.2 cells has been identified and shown to be involved in the high level of induced transcription activity when the ERE is placed at a distance from the promoter. Finally, a hormone-controlled in vitro transcription system derived from Xenopus liver nuclear extracts was exploited to characterize two additional novel cis-acting elements within the vitellogenin gene B1 promoter. One of them, a negative regulatory element (NRE), is responsible for repression of promoter activity in the absence of hormone. The second is related to the NF-I binding site and is required, together with the ERE, to mediate hormonal induction. Moreover, we detected three trans-acting activities in Xenopus liver nuclear extracts that interact with these regions and demonstrated that they participate in the regulation of the expression of the vitellogenin promoter in vitro.

Numerical Methods Using B-Splines

NASA Technical Reports Server (NTRS)

Shariff, Karim; Merriam, Marshal (Technical Monitor)

1997-01-01

The seminar will discuss (1) The current range of applications for which B-spline schemes may be appropriate (2) The property of high-resolution and the relationship between B-spline and compact schemes (3) Comparison between finite-element, Hermite finite element and B-spline schemes (4) Mesh embedding using B-splines (5) A method for the incompressible Navier-Stokes equations in curvilinear coordinates using divergence-free expansions.

Relationship between soil cobalt and vitamin B12 levels in the liver of livestock in Saudi Arabia: role of competing elements in soils.

PubMed

Huwait, Etimad A; Kumosani, Taha A; Moselhy, Said S; Mosaoa, Rami M; Yaghmoor, Soonham S

2015-09-01

This study aimed to analyze the agricultural soils from different regions in Saudi Arabia for cobalt and related metals as Cu(2+), Ni(2+), Cr(3+), Zn(2+) and Pb(2+). Liver and muscle tissues of livestock grazing on the selected areas were analyzed for the content of Co and vitamin B12. Our results indicated that the levels of Co in surface soil (0-15 cm) were higher than in sub-surface soil (>15 cm-45 cm). In contrast, Pb and Zn were higher in sub-surface soil than in surface soil. A significant positive correlation existed between the levels of Co and vitamin B12 in the liver of livestock. However, Co was not detected in muscle tissues while vitamin B12 was present at very low levels in comparison with the levels found in the liver. The results indicated that Zn(2+), Pb(2+) compete with Co in soil, which eventually affected the levels of vitamin B12 in liver. It was recommended that survey of heavy metals in grazing fields of cattle should consider inclusion of multiple elements that compete with the bioavailability of essential elements in plants and animals for the prevention of deficiency of essential elements such as Co.

A spectral model for signal elements isolated from zebrafish photopic electroretinogram

PubMed Central

Nelson, Ralph; Singla, Nirmish

2009-01-01

The zebrafish photopic ERG sums isolatable elements. In each element red, blue, green and UV (r, g, b, u) cone signals combine in a way that reflects retinal organization. ERG responses to monochromatic stimuli of different wavelengths and irradiances were recorded on a white, rod suppressing background using superfused eyecups. Onset elements were isolated with glutamatergic blockers and response subtractions. CNQX blocked ionotropic (AMPA/kainate) glutamate receptors; L-AP4 or CPPG blocked metabotropic (mGluR6) glutamate receptors; TBOA blocked glutamate transporters; and L-Aspartate inactivated all glutamatergic mechanisms. Seven elements emerged: photopic PIII, the L-Aspartate-isolated cone response; b1, a CNQX-sensitive early b-wave element of inner retinal origin; PII, a photopic, CNQX-insensitive, composite b-wave element from ON bipolar cells; PIIm, an L-AP4/CPPG-sensitive, CNQX-insensitive metabotropic sub-element of PII; PIInm, an L-AP4/CPPG/CNQX-insensitive, non-metabotropic sub-element of PII; a1nm, a TBOA-sensitive, CNQX/L-AP4/CPPG-insensitive, non-metabotropic, post-photoreceptor a-wave element; and a2, a CNQX-sensitive a-wave element linked to OFF bipolar cells. The first five elements were fit with a spectral model that demonstrates independence of cone color pathways. From this Vmax and half-saturation values (k) for the contributing r- g- b- and u-cone signals were calculated. Two signal patterns emerged. For PIII or PIInm the Vmax order was Vr > Vg ≫ Vb ≈ Vu. For b1, PII, and PIIm the Vmax order was Vr ≈ Vb > Vg > Vu. In either pattern u-cone amplitude (Vu) was smallest, but u-cone sensitivity (ku362) was greatest, some 10-30 times greater than r-cone (kr570). The spectra of b1/PII/PIIm elements peaked near b-cone and u-cone absorbance maxima regardless of criteria, but the spectra of PIII/PIInm elements shifted from b- towards r-cone absorbance maxima as criterion levels increased. The greatest gains in Vmax relative to PIII occurred for the b- and u-cone signals in the b1/PII/PIIm b-wave elements. This suggests a high-gain, prolific metabotropic circuitry for b- and u-cone bipolar cells. PMID:19723365

Telomeric P elements associated with cytotype regulation of the P transposon family in Drosophila melanogaster.

PubMed Central

Stuart, Jeremy R; Haley, Kevin J; Swedzinski, Douglas; Lockner, Samuel; Kocian, Paul E; Merriman, Peter J; Simmons, Michael J

2002-01-01

P elements inserted at the left end of the Drosophila X chromosome were isolated genetically from wild-type P strains. Stocks carrying these elements were tested for repression of P-strain-induced gonadal dysgenesis in females and for repression of transposase-catalyzed P-element excision in males and females. Both traits were repressed by stocks carrying either complete or incomplete P elements inserted near the telomere of the X chromosome in cytological region 1A, but not by stocks carrying only nontelomeric X-linked P elements. All three of the telomeric P elements that were analyzed at the molecular level were inserted in one of the 1.8-kb telomere-associated sequence (TAS) repeats near the end of the X chromosome. Stocks with these telomeric P elements strongly repressed P-element excision induced in the male germline by a P strain or by the transposase-producing transgenes H(hsp/CP)2, H(hsp/CP)3, a combination of these two transgenes, and P(ry(+), delta2-3)99B. For H(hsp/CP)2 and P(ry(+), delta2-3)99B, the repression was also effective when the flies were subjected to heat-shock treatments. However, these stocks did not repress the somatic transposase activity of P(ry(+), delta2-3)99B. Repression of transposase activity in the germline required maternal transmission of the telomeric P elements themselves. Paternal transmission of these elements, or maternal transmission of the cytoplasm from carriers, both were insufficient to repress transposase activity. Collectively, these findings indicate that the regulatory abilities of telomeric P elements are similar to those of the P cytotype. PMID:12524339

34 CFR Appendix B to Part 379 - Presumption of Eligibility

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 2 2014-07-01 2013-07-01 true Presumption of Eligibility B Appendix B to Part 379 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION PROJECTS WITH INDUSTRY Pt. 379, App. B Appendix B...

34 CFR Appendix B to Part 379 - Presumption of Eligibility

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 2 2010-07-01 2010-07-01 false Presumption of Eligibility B Appendix B to Part 379 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION PROJECTS WITH INDUSTRY Pt. 379, App. B Appendix B...

Solar-B E/PO Program at Chabot Space and Science Center, Oakland, California

NASA Astrophysics Data System (ADS)

Burress, B. S.

2005-05-01

Chabot Space and Science Center in Oakland, California, conducts the Education/Public Outreach program for the Lockheed-Martin Solar and Astrophysics Lab Solar-B Focal Plane Package project. Since opening its doors in August 2000, Chabot has carried out this program in activities and educational products in the public outreach, informal education, and formal education spheres. We propose a poster presentation that illustrates the spectrum of our Solar-B E/PO program. Solar-B, scheduled to launch in September 2006, is another step in an increasingly sophisticated investigation and understanding of our Sun, its behavior, and its effects on the Earth and our technological civilization. A mission of the Japan Aerospace Exploration Agency (JAXA), Solar-B is an international collaboration between Japan, the US/NASA, and the UK/PPARC. Solar-B's main optical telescope, extreme ultraviolet imaging spectrometer, and x-ray telescope will collect data on the Sun's magnetic dynamics from the photosphere through the corona at higher spatial and time resolution than on current and previous solar satellite missions, furthering our understanding of the Sun's behavior and, ultimately, its effects on the Earth. Chabot's E/PO program for the Lockheed-Martin Solar-B Focal Plane Package is multi-faceted, including elements focused on technology/engineering, solar physics, and Sun-Earth Connection themes. In the Public Outreach arena, we conduct events surrounding NASA Sun-Earth Day themes and programs other live and/or interactive events, facilitate live solar viewing, and present a series of exhibits focused on the Solar-B and other space-based missions, the dynamic Sun, and light and optics. In the Informal Education sector we run a solar day camp for kids and produce educational products, including a poster on the Solar-B mission and CDROM multimedia packages. In Formal Education, we develop classroom curriculum guides and conduct workshops training teachers in their implementation. Our poster presentation will address the highlights of our program in all three of these areas.

Response of basic structural elements and B-52 structural components to simulated nuclear overpressure. Volume I-program description and results (basic structural elements). Final report, 1 June 1977-30 September 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Syring, R.P.; Grubb, R.L.

1979-09-30

This document reports on the following: (1) experimental determination of the response of 16 basic structural elements and 7 B-52 components to simulated nuclear overpressure environments (utilizing Sandia Corporation's Thunderpipe Shock Tube), (2) analysis of these test specimens utilizing the NOVA-2 computer program, and (3) correlation of test and analysis results.

38 CFR 21.84 - Individualized written rehabilitation plan.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Vocational Rehabilitation and Employment Under 38 U.S.C...) Identify goals and objectives to be achieved by the veteran during the period of rehabilitation services... the veteran to achieve the goals and objectives of the plan. (Authority: 38 U.S.C. 3107) (b) Elements...

76 FR 71044 - International Conference on Harmonisation; E2B(R3) Electronic Transmission of Individual Case...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-16

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-D-0720...; Draft Guidance on Implementation; Data Elements and Message Specification; Appendix on Backwards and...): Implementation Guide--Data Elements and Message Specification'' (the draft E2B(R3) implementation guidance) and...

Montessori education: a review of the evidence base

NASA Astrophysics Data System (ADS)

Marshall, Chloë

2017-10-01

The Montessori educational method has existed for over 100 years, but evaluations of its effectiveness are scarce. This review paper has three aims, namely to (1) identify some key elements of the method, (2) review existing evaluations of Montessori education, and (3) review studies that do not explicitly evaluate Montessori education but which evaluate the key elements identified in (1). The goal of the paper is therefore to provide a review of the evidence base for Montessori education, with the dual aspirations of stimulating future research and helping teachers to better understand whether and why Montessori education might be effective.

NF-kappaB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitro.

PubMed

Feng, Jian Q; Xing, Lianping; Zhang, Jiang-Hong; Zhao, Ming; Horn, Diane; Chan, Jeannie; Boyce, Brendan F; Harris, Stephen E; Mundy, Gregory R; Chen, Di

2003-08-01

Bone morphogenetic protein-2 (BMP-2) regulates growth plate chondrogenesis during development and postnatal bone growth, but the control mechanisms of BMP-2 expression in growth plate chondrocytes are unknown. Here we have used both in vitro and in vivo approaches to demonstrate that transcription factor, NF-kappaB, regulates BMP-2 gene expression in chondrocytes. Two putative NF-kappaB response elements were found in the -2712/+165 region of the BMP-2 gene. Cotransfection of mutant I-kappaBalpha expression plasmids with BMP-2 promoter-luciferase reporters into TMC-23 chondrocyte cell line suppressed BMP-2 transcription. Mutations in NF-kappaB response elements in the BMP-2 gene lead to decreases in BMP-2 promoter activity. Electrophoretic mobility shift assay using nuclear extracts from TMC-23 chondrocytic cells revealed that the NF-kappaB subunits p50 and p65 bound to the NF-kappaB response elements of the BMP-2 gene. Thus, NF-kappaB may positively regulate BMP-2 gene transcription. Consistent with these findings, expression of BMP-2 mRNA was significantly reduced in growth plate chondrocytes in NF-kappaB p50/p52 dKO mice, which associated with decreased numbers of 5-bromo-2'-deoxyuridine (BrdUrd)-positive cells in the proliferating zone of growth plate in these mice. Therefore, in postnatal growth plate chondrocytes, expression of BMP-2 is regulated by NF-kappaB, which may play an important role in chondrogenesis.

High Frequency Ultrasound Array Designed for Ultrasound Guided Breast Biopsy

PubMed Central

Cummins, Thomas; Eliahoo, Payam; Shung, K. Kirk

2016-01-01

This paper describes the development of a miniaturized high frequency linear array that can be integrated within a core biopsy needle to improve tissue sampling accuracy during breast cancer biopsy procedures. The 64 element linear array has an element width of 14 μm, kerf width of 6 μm, element length of 1 mm and element thickness of 24 μm. The 2–2 array composite was fabricated using deep reactive ion etching of PMN-PT single crystal material. The array composite fabrication process as well as a novel high density electrical interconnect solution are presented and discussed. Array performance measurements show that the array had a center frequency and fractional bandwidth (−6 dB) of 59.1 MHz and 29.4%, respectively. Insertion loss and adjacent element cross talk at the center frequency were −41.0 dB and −23.7 dB, respectively. A B-mode image of a tungsten wire target phantom was captured using a synthetic aperture imaging system and the imaging test results demonstrate axial and lateral resolutions of 33.2 μm and 115.6 um, respectively. PMID:27046895

Toward an evidence-based patient-provider communication in rehabilitation: linking communication elements to better rehabilitation outcomes.

PubMed

Jesus, Tiago Silva; Silva, Isabel Lopes

2016-04-01

There is a growing interest in linking aspects of patient-provider communication to rehabilitation outcomes. However, the field lacks a conceptual understanding on: (a) 'how' rehabilitation outcomes can be improved by communication; and (b) through 'which' elements in particular. This article elaborates on the conceptual developments toward informing further practice and research. Existing models of communication in healthcare were adapted to rehabilitation, and its outcomes through a comprehensive literature review. After depicting mediating mechanisms and variables (e.g. therapeutic engagement, adjustment toward disability), this article presents the '4 Rehab Communication Elements' deemed likely to underpin rehabilitation outcomes. The four elements are: (a) knowing the person and building a supportive relationship; (b) effective information exchange and education; (c) shared goal-setting and action planning; and (d) fostering a more positive, yet realistic, cognitive and self-reframing. This article describes an unprecedented, outcomes-oriented approach toward the design of rehabilitation communication, which has resulted in the development of a new intervention model: the '4 Rehab Communication Elements'. Further trials are needed to evaluate the impact of this whole intervention model on rehabilitation outcomes. © The Author(s) 2015.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ferreira, A. S.; Rovani, P. R.; Lima, J. C. de, E-mail: joao.cardoso.lima@ufsc.br

A nanostructured Ti{sub 50}Ni{sub 25}Fe{sub 25} phase (B2) was formed by mechanical alloying and its structural stability was studied as a function of pressure. The changes were followed by X-ray diffraction. The B2 phase was observed up to 7 GPa; for larger pressures, the B2 phase transformed into a trigonal/hexagonal phase (B19) that was observed up to the highest pressure used (18 GPa). Besides B2 and B19, elemental Ni or a SS-(Fe,Ni) and FeNi{sub 3} were observed. With decompression, the B2 phase was recovered. Using in situ angle-dispersive X-ray diffraction patterns, the single line method was applied to obtain the apparent crystallitemore » size and the microstrain for both the B2 and the B19 phases as a function of the applied pressure. Values of the bulk modulus for the B2, B19, elemental Ni or SS-(Fe,Ni) and FeNi{sub 3} phases were obtained by fitting the pressure dependence of the volume to a Birch–Murnaghan equation of state (BMEOS)« less

Retrotransposons of the Tnt1B family are mobile in Nicotiana plumbaginifolia and can induce alternative splicing of the host gene upon insertion.

PubMed

Leprinc, A S; Grandbastien, M A; Christian, M

2001-11-01

Active retrotransposons have been identified in Nicotiana plumbaginifolia by their ability to disrupt the nitrate reductase gene in chlorate-resistant mutants selected from protoplast-derived cultures. In mutants E23 and F97, two independent insertions of Tnp2, a new retrotransposon closely related to the tobacco Tnt1 elements, were detected in the nitrate reductase gene. These two Tnp2 elements are members of the Tnt1B subfamily which shows that Tnt1B elements can be active and mutagenic in the N. plumbaginifolia genome. Furthermore, these results suggest that Tnt1B is the most active family of Tntl elements in N. plumbaginifolia, whereas in tobacco only members of the Tnt1A subfamily were found inserted in the nitrate reductase gene. The transcriptional regulations of Tnp2 and Tnt1A elements are most probably different due to non-conserved U3 regions. Our results thus support the hypothesis that different Nicotiana species contain different active Tntl subfamilies and that only one active Tntl subfamily might be maintained in each of these species. The Tnp2 insertion found in the F97 mutant was found to be spliced out of the nitrate reductase mRNA by activation of cryptic donor and acceptor sites in the nitrate reductase and the Tnp2 sequences respectively.

Nurse Educator Perceptions of the Importance of Relationship in Online Teaching and Learning.

PubMed

Smith, Yvonne M; Crowe, Alicia R

The purpose of this study was to understand the perceptions of teaching nursing students in online environments as experienced by nursing educators who have been teaching online for a minimum of 2 years. The study used an interview-based qualitative descriptive design. Semistructured interviews with 10 full-time nurse educators were conducted. The participants represented a range of ranks and teaching experience. Analysis involved a constant comparative process of initial and focused coding. Relationships were important to these nurse educators, and there was an interconnected nature among (a) student engagement and learning, (b) "knowing students," and (c) helping students meet their needs. Although different in how they experienced these elements, they seemed to share a sense that you have to know your students to help them meet their needs, and that you have to help them meet their needs so that they can learn, and building relationships within the online environment is key to all if this. Relationships are the heart of nursing and, for these nurse educators, a key aspect of nursing education. Having a strong relationship between nurse educators and nursing students supports student engagement in learning online. With continually increasing online nurse education, understanding these relationships is important to improve nursing education and consequently improve nursing practice. Copyright © 2016 Elsevier Inc. All rights reserved.

Inelastic scattering matrix elements for the nonadiabatic collision B(2P1/2)+H2(1Sigmag+,j)<-->B(2P3/2)+H2(1Sigmag+,j').

PubMed

Weeks, David E; Niday, Thomas A; Yang, Sang H

2006-10-28

Inelastic scattering matrix elements for the nonadiabatic collision B(2P1/2)+H2(1Sigmag+,j)<-->B(2P3/2)+H2(1Sigmag+,j') are calculated using the time dependent channel packet method (CPM). The calculation employs 1 2A', 2 2A', and 1 2A" adiabatic electronic potential energy surfaces determined by numerical computation at the multireference configuration-interaction level [M. H. Alexander, J. Chem. Phys. 99, 6041 (1993)]. The 1 2A' and 2 2A', adiabatic electronic potential energy surfaces are transformed to yield diabatic electronic potential energy surfaces that, when combined with the total B+H2 rotational kinetic energy, yield a set of effective potential energy surfaces [M. H. Alexander et al., J. Chem. Phys. 103, 7956 (1995)]. Within the framework of the CPM, the number of effective potential energy surfaces used for the scattering matrix calculation is then determined by the size of the angular momentum basis used as a representation. Twenty basis vectors are employed for these calculations, and the corresponding effective potential energy surfaces are identified in the asymptotic limit by the H2 rotor quantum numbers j=0, 2, 4, 6 and B electronic states 2Pja, ja=1/2, 3/2. Scattering matrix elements are obtained from the Fourier transform of the correlation function between channel packets evolving in time on these effective potential energy surfaces. For these calculations the H2 bond length is constrained to a constant value of req=1.402 a.u. and state to state scattering matrix elements corresponding to a total angular momentum of J=1/2 are discussed for j=0<-->j'=0,2,4 and 2P1/2<-->2P1/2, 2P3/2 over a range of total energy between 0.0 and 0.01 a.u.

"Observation-Projet": A Professional Tool for Caregivers. Two Experiences in Italian Day-Care Settings

ERIC Educational Resources Information Center

Molina, Paola; Marotta, Monica; Bulgarelli, Daniela

2016-01-01

Ability to reflect on practice is a key element of early childhood professionalism and is positively associated with the quality of educational services. "Observation-Projet" (Fontaine 2008, 2011b) is a method designed to support practitioners' reflection through the observational process. The method adapts the required scientific…

7 CFR 15b.39 - Education of institutionalized persons.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 1 2011-01-01 2011-01-01 false Education of institutionalized persons. 15b.39 Section... § 15b.39 Education of institutionalized persons. A recipient to which this subpart applies that operates...)(2), in its program or activity is provided an appropriate education, as defined in § 15b.22(b...

7 CFR 15b.39 - Education of institutionalized persons.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 1 2012-01-01 2012-01-01 false Education of institutionalized persons. 15b.39 Section... § 15b.39 Education of institutionalized persons. A recipient to which this subpart applies that operates...)(2), in its program or activity is provided an appropriate education, as defined in § 15b.22(b...

7 CFR 15b.39 - Education of institutionalized persons.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 1 2014-01-01 2014-01-01 false Education of institutionalized persons. 15b.39 Section... § 15b.39 Education of institutionalized persons. A recipient to which this subpart applies that operates...)(2), in its program or activity is provided an appropriate education, as defined in § 15b.22(b...

7 CFR 15b.39 - Education of institutionalized persons.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 1 2013-01-01 2013-01-01 false Education of institutionalized persons. 15b.39 Section... § 15b.39 Education of institutionalized persons. A recipient to which this subpart applies that operates...)(2), in its program or activity is provided an appropriate education, as defined in § 15b.22(b...

7 CFR 15b.39 - Education of institutionalized persons.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 1 2010-01-01 2010-01-01 false Education of institutionalized persons. 15b.39 Section... § 15b.39 Education of institutionalized persons. A recipient to which this subpart applies that operates...)(2), in its program or activity is provided an appropriate education, as defined in § 15b.22(b...

Eight-Element Antenna Array for LTE 3.4-3.8 GHz Mobile Handset Applications

NASA Astrophysics Data System (ADS)

Yang, Lingsheng; Ji, Ming; Cheng, Biyu; Ni, Bo

2017-05-01

In this letter, an eight-element Multiple-input multiple-output (MIMO) antenna system for LTE mobile handset applications is proposed. The antenna array consists of eight 3D inverted F-shaped antennas (3D-IFA), and the measured -10 dB impedance bandwidth is 3.2-3.9 GHz which can cover the LTE bands 42 and 43 (3.4-3.8 GHz). By controlling the rotation of the antenna elements, no less than 10 dB isolation between antenna elements can be obtained. After using the specially designed meandered slots on the ground as decoupling structures, the measured isolation can be further improved to higher than 13 dB between the antenna elements at the whole operating band.

L1-mediated retrotransposition of murine B1 and B2 SINEs recapitulated in cultured cells.

PubMed

Dewannieux, Marie; Heidmann, Thierry

2005-06-03

SINEs are short interspersed nucleotide elements with transpositional activity, present at a high copy number (up to a million) in mammalian genomes. They are 80-400 bp long, non-coding sequences which derive either from the 7SL RNA (e.g. human Alus, murine B1s) or tRNA (e.g. murine B2s) polymerase III-driven genes. We have previously demonstrated that Alus very efficiently divert the enzymatic machinery of the autonomous L1 LINE (long interspersed nucleotide element) retrotransposons to transpose at a high rate. Here we show, using an ex vivo assay for transposition, that both B1 and B2 SINEs can be mobilized by murine LINEs, with the hallmarks of a bona fide retrotransposition process, including target site duplications of varying lengths and integrations into A-rich sequences. Despite different phylogenetic origins, transposition of the tRNA-derived B2 sequences is as efficient as that of the human Alus, whereas that of B1s is 20-100-fold lower despite a similar high copy number of these elements in the mouse genome. We provide evidence, via an appropriate nucleotide substitution within the B1 sequence in a domain essential for its intracellular targeting, that the current B1 SINEs are not optimal for transposition, a feature most probably selected for the host sake in the course of evolution.

47 CFR 97.501 - Qualifying for an amateur operator license.

Code of Federal Regulations, 2010 CFR

2010-10-01

....501 Section 97.501 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL... must pass, or otherwise receive examination credit for, the following examination elements: (a) Amateur Extra Class operator: Elements 2, 3, and 4; (b) General Class operator: Elements 2 and 3; (c) Technician...

Semiconducting icosahedral boron arsenide crystal growth for neutron detection

NASA Astrophysics Data System (ADS)

Whiteley, C. E.; Zhang, Y.; Gong, Y.; Bakalova, S.; Mayo, A.; Edgar, J. H.; Kuball, M.

2011-03-01

Semiconducting icosahedral boron arsenide, B12As2, is an excellent candidate for neutron detectors, thermoelectric converters, and radioisotope batteries, for which high quality single crystals are required. Thus, the present study was undertaken to grow B12As2 crystals by precipitation from metal solutions (nickel) saturated with elemental boron (or B12As2 powder) and arsenic in a sealed quartz ampoule. B12As2 crystals of 10-15 mm were produced when a homogeneous mixture of the three elements was held at 1150 °C for 48-72 h and slowly cooled (3.5 °C/h). The crystals varied in color and transparency from black and opaque to clear and transparent. X-ray topography (XRT), and elemental analysis by energy dispersive X-ray spectroscopy (EDS) confirmed that the crystals had the expected rhombohedral structure and chemical stoichiometry. The concentrations of residual impurities (nickel, carbon, etc.) were low, as measured by Raman spectroscopy and secondary ion mass spectrometry (SIMS). Additionally, low etch-pit densities (4.4×107 cm-2) were observed after etching in molten KOH at 500 °C. Thus, the flux growth method is viable for growing large, high-quality B12As2 crystals.

The Annual Pennsylvania Conference on Post-Secondary Occupational Education (2nd).

ERIC Educational Resources Information Center

Gillie, Angelo C., Ed.

This conference on the evaluation and effectiveness of postsecondary occupational education was for the purposes of: (1) providing presentations on evaluation of postsecondary occupational education in terms of programs, faculty, and institutions, (2) providing information that would better enable participants to identify some elements for…

26 CFR 31.3121(b)(8)-2 - Services in employ of religious, charitable, educational, or certain other organizations exempt...

Code of Federal Regulations, 2010 CFR

2010-04-01

..., educational, or certain other organizations exempt from income tax. 31.3121(b)(8)-2 Section 31.3121(b)(8)-2... COLLECTION OF INCOME TAX AT SOURCE EMPLOYMENT TAXES AND COLLECTION OF INCOME TAX AT SOURCE Federal Insurance... employ of religious, charitable, educational, or certain other organizations exempt from income tax. (a...

News of Higher Educational Institutions, Ministry of Higher Education USSR, Radiophysics Series

DTIC Science & Technology

1960-12-30

formulate the following proposition: • • 2. " Theorem 2. If the elements AyA ^i (i^t j) of the ; determinant D ,, T*ose diagonal elements...34 OFFICE OF TECHNICAL SERVICES Ü. S. DEPARTMENT OF COMMERCE WASHINGTON 1% D * Ce U. S.’ JOINT PUBLICATIONS RESEARCH SERVICE 1636 CONNECTICUT AVE...N.W. WASHINGTON Z% D , C. FOREWORD "il ELIS publication vas ’.prepared under ■ contract "by the \\JKITED SPATES , JOIET’PUBLICATIONS RE- SEARCH

Federal Logistics Information Systems. FLIS Procedures Manual. Document Identifier Code Input/Output Formats (Variable Length). Volume 9.

DTIC Science & Technology

1997-04-01

DATA COLLABORATORS 0001N B NQ 8380 NUMBER OF DATA RECEIVERS 0001N B NQ 2533 AUTHORIZED ITEM IDENTIFICATION DATA COLLABORATOR CODE 0002 ,X B 03 18 TD...01 NC 8268 DATA ELEMENT TERMINATOR CODE 000iX VT 9505 TYPE OF SCREENING CODE 0001A 01 NC 8268 DATA ELEMENT TERMINATOR CODE 000iX VT 4690 OUTPUT DATA... 9505 TYPE OF SCREENING CODE 0001A 2 89 2910 REFERENCE NUMBER CATEGORY CODE (RNCC) 0001X 2 89 4780 REFERENCE NUMBER VARIATION CODE (RNVC) 0001 N 2 89

The Orthopaedic Training Study, Phase II 1968-1972. Final Report Supplement, Psychomotor Skills, Part B.

ERIC Educational Resources Information Center

Olson, Carl J.; And Others

This document, as a supplement to the final report of the Orthopaedic Training Study, presents a discussion of the rationale behind the implementation of a laboratory course in psychomotor skills development for medical students. Medical educators examined resident training in terms of 3 components of cognitive elements of learning: cognitive,…

"The Second We Stop Growing We Are Dead": Examining a Middle Grades Social Studies Professional Dyad

ERIC Educational Resources Information Center

Gradwell, Jill M.; DiCamillo, Lorrei

2013-01-01

Teacher collaboration is an important part of professional growth (Coburn, 2001; DuFour, 2004b; Grossman, Wineburg, & Woolworth, 2001; Little, 2002) and has been found to be a key element in highly successful schools (McEwin & Greene, 2010). Additionally, the Association for Middle Level Education (AMLE), formerly National Middle School…

75 FR 31771 - Office of Elementary and Secondary Education

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-04

... DEPARTMENT OF EDUCATION Office of Elementary and Secondary Education Overview Information; Impact... 8007(b)(2)(A) of the Elementary and Secondary Education Act of 1965, as amended (Act) (20 U.S.C. 7707(b... 2007.) Program Authority: 20 U.S.C. 7707(b). Applicable Regulations: (a) The Education Department...

Systems of Generators for the Normalizers of Certain Elements of the Braid Group

NASA Astrophysics Data System (ADS)

Gurzo, G. G.

1985-06-01

Systems of generators of normalizers are determined for certain elements of the braid group {\\mathfrak{B}}_{n+1}. These systems of generators consist of fewer than 2n explicitly written words in the positive alphabet of {\\mathfrak{B}}_{n+1}. Bibliography: 10 titles.

Autism, "recovery (to normalcy)", and the politics of hope.

PubMed

Broderick, Alicia A

2009-08-01

This article draws on the traditions of critical discourse analysis (N. Fairclough, 1995, 2001; M. Foucault, 1972, 1980; J. P. Gee, 1999) in critically examining the discursive formation of "recovery" from autism in applied behavioral analysis (ABA) discourse and its relationship to constructs of hope. Constituted principally in the work of O. I. Lovaas (1987) and C. Maurice (1993), and central to ABA discourse on recovery, has been the construction of a particular vision of hope that has at least 2 integral conceptual elements: (a) Hope for recovery within ABA discourse is constructed in binary opposition to hopelessness, and (b) recovery within ABA discourse is discursively constructed as "recovery (to normalcy)." The author analyzes these 2 pivotal ABA texts within the context of an analysis of other uses of the term recovery in broader bodies of literature: (a) within prior autism-related literature, particularly autobiography, and (b) within literature emanating from the psychiatric survivors' movement. If, indeed, visions of hope inform educational policy and decision making, this analysis addresses S. Danforth's (1997) cogent query, "On what basis hope?", and asserts that moral and political commitments should be central sources of visions of hope and, therefore, inform educational policy and decision making for young children with labels of autism.

E2F mediates induction of the Sp1-controlled promoter of the human DNA polymerase ɛ B-subunit gene POLE2

PubMed Central

Huang, Deqi; Jokela, Maarit; Tuusa, Jussi; Skog, Sven; Poikonen, Kari; Syväoja, Juhani E.

2001-01-01

The B-subunits of replicative DNA polymerases from Archaea to humans belong to the same protein family, suggesting that they share a common fundamental function. We report here the gene structure for the B-subunit of human DNA polymerase ɛ (POLE2), whose expression and transcriptional regulation is typical for replication proteins with some unique features. The 75 bp core promoter region, located within exon 1, contains an Sp1 element that is a critical determinant of promoter activity as shown by the luciferase reporter, electrophoretic mobility shift and DNase I footprinting assays. Two overlapping E2F elements adjacent to the Sp1 element are essential for full promoter activity and serum response. Binding sites for E2F1 and NF-1 reside immediately downstream from the core promoter region. Our results suggest that human POLE2 is regulated by two E2F–pocket protein complexes, one associated with Sp1 and the other with NF-1. So far, only one replicative DNA polymerase B-subunit gene promoter, POLA2 encoding the B-subunit of DNA polymerase α, has been characterized. Mitogenic activation of the POLE2 promoter by an E2F-mediated mechanism resembles that of POLA2, but the regulation of basal promoter activity is different between these two genes. PMID:11433027

A Higher-Order Conservation Element Solution Element Method for Solving Hyperbolic Differential Equations on Unstructured Meshes

DTIC Science & Technology

2014-03-01

Unclassified c. THIS PAGE Unclassified SAR 232 19b. TELEPHONE NO (include area code) 661 275-5649 Standard Form 298 (Rev. 8-98) Prescribed by ANSI ...34 # ∂ Cfx ,yi ∗ (x, y, t) ∂xI∂yJ∂tK = A∑ a=0 A−a∑ b=0 A−a−b∑ c=0 ( ∂Bfx,yi ∂xI+a∂yJ+b∂tK+c )n j Δxa a...A−a∑ b=0 A−a−b∑ c=0 ( ∂a+b+ cfx ,yi ∂xa∂yb∂tc )n−1/2 1′× (x− x1′×) a (y − y1′×) b ( t− tn−1/2 )c a!b!c

Beta cell device using icosahedral boride compounds

DOEpatents

Aselage, Terrence L.; Emin, David

2002-01-01

A beta cell for converting beta-particle energies into electrical energy having a semiconductor junction that incorporates an icosahedral boride compound selected from B.sub.12 As.sub.2, B.sub.12 P.sub.2, elemental boron having an .alpha.-rhombohedral structure, elemental boron having a .beta.-rhombohedral structure, and boron carbides of the chemical formula B.sub.12-x C.sub.3-x, where 0.15

Access to Higher Education in the European Community: Synthesis Report (Volume 1) and Country Reports (Volume 2).

ERIC Educational Resources Information Center

de Jonge, J. F. M.; And Others

This report examines, country by country, the present state of student access to higher education institutions in the Member States of the European Community (EC), as well as the elements which affect access directly and the elements which can potentially have an effect on access. Volume 1 of the report gives an overview of the methods of data…

Novel Approaches for Mutual Coupling Reduction among Vertical and Planar Monopole Elements

NASA Astrophysics Data System (ADS)

Isaac, Ayman A.

Modern wireless systems such as 4G LTE-A, RFID, Wi-Fi, WiMAX, and GPS utilize miniaturized antenna array elements to improve performance and reliability through diversity and increase throughput using spatial multiplexing schemes of MIMO systems. One original contribution in this thesis is to significantly reduce the complexity of traditional design approaches targeting mutual coupling reductions such as metamaterials, defected ground plane structures, soft electromagnetic surfaces using novel design alternatives. A decoupling network is proposed, which consists of a rectangular metallic ring along with two tuning strips printed on a dielectric substrate, surrounding a two-element monopole antenna array fed by a coplanar waveguide or microstrip structure. The array design offers a reduction in mutual coupling level by around 20 dB at 2.4 GHz as compared to the same array in which the two monopoles share the same ground plane but without the decoupling network. The array achieves a -10 dB S11 bandwidth of 0.63 GHz, (2.12 GHz - 2.75 GHz), a 0.24 GHz (2.33 GHz - 2.57 GHz) bandwidth in which S21 is less than -20 dB, respectively. A total realized gain of 1.6 to 1.69 dB in the frequency range over which S11 and S21 is less than -10 dB and -20 dB respectively. The boresight of the radiation patterns of two vertical monopole wire antennas operating at 2.4 GHz and separated by 8 mm are shown to be orthogonal and inclined by 45° with respect to the horizon while maintaining the shape of the isolated single antenna element. Hence, we denote this design as the descattered and decoupled orthogonal MIMO antenna array, which is reported for the first time in this dissertation, providing the ideal far-field radiation characteristics as theoretically deemed for handheld MIMO devices. Moreover, two new approaches for the reduction of mutual coupling between two rectangular planar monopole antennas printed on a dielectric substrate with a partial ground plane are presented in this thesis. In the first design, two thin strips are attached to the adjacent corners of the radiating elements and extend to a certain distance above the partial ground plane. Results reveal a mutual coupling less than -20 dB over the frequency range from 2.16 GHz up to 2.74 GHz. while maintaining the -10 dB reflection coefficient bandwidth. Three implementations are presented which demonstrate an envelope correlation coefficient below 0.06 when the antenna elements are separated by 0.04lambda o, 0.048lambdao, 0.064lambdao, and 0.085lambda o with lambdao calculated at 1.5 GHz, 1.8 GHz, 2.4 GHz, and 3.2 GHz, respectively. The second design employs a decoupling structure consisting of planar or meander strip extending along the partial ground, the space between the two antenna elements, and beyond by a certain extent. The antennas provide a realized gain of 4.39 dB and 4.66 dB at 2.4 GHz using strip and meander lines, respectively, and bandwidth of (1.65 GHz- 4 GHz) and (1.43 GHz - 3.7 GHz), respectively. The two antenna arrays consisting of planar and meander strip achieve an envelope correlation coefficient of 0.05 and 0.06, respectively.

24 CFR 401.400 - Required elements of a Restructuring Plan.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Required elements of a... RESTRUCTURING PROGRAM (MARK-TO-MARKET) Restructuring Plan § 401.400 Required elements of a Restructuring Plan... included in its PRA. (b) Required elements. The Restructuring Plan must contain a narrative that fully...

24 CFR 401.400 - Required elements of a Restructuring Plan.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Required elements of a... RESTRUCTURING PROGRAM (MARK-TO-MARKET) Restructuring Plan § 401.400 Required elements of a Restructuring Plan... included in its PRA. (b) Required elements. The Restructuring Plan must contain a narrative that fully...

24 CFR 401.400 - Required elements of a Restructuring Plan.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Required elements of a... RESTRUCTURING PROGRAM (MARK-TO-MARKET) Restructuring Plan § 401.400 Required elements of a Restructuring Plan... included in its PRA. (b) Required elements. The Restructuring Plan must contain a narrative that fully...

24 CFR 401.400 - Required elements of a Restructuring Plan.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Required elements of a... RESTRUCTURING PROGRAM (MARK-TO-MARKET) Restructuring Plan § 401.400 Required elements of a Restructuring Plan... included in its PRA. (b) Required elements. The Restructuring Plan must contain a narrative that fully...

24 CFR 401.400 - Required elements of a Restructuring Plan.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Required elements of a... RESTRUCTURING PROGRAM (MARK-TO-MARKET) Restructuring Plan § 401.400 Required elements of a Restructuring Plan... included in its PRA. (b) Required elements. The Restructuring Plan must contain a narrative that fully...

Description and effects of sequential behavior practice in teacher education.

PubMed

Sharpe, T; Lounsbery, M; Bahls, V

1997-09-01

This study examined the effects of a sequential behavior feedback protocol on the practice-teaching experiences of undergraduate teacher trainees. The performance competencies of teacher trainees were analyzed using an alternative opportunities for appropriate action measure. Data support the added utility of sequential (Sharpe, 1997a, 1997b) behavior analysis information in systematic observation approaches to teacher education. One field-based undergraduate practicum using sequential behavior (i.e., field systems analysis) principles was monitored. Summarized are the key elements of the (a) classroom instruction provided as a precursor to the practice teaching experience, (b) practice teaching experience, and (c) field systems observation tool used for evaluation and feedback, including multiple-baseline data (N = 4) to support this approach to teacher education. Results point to (a) the strong relationship between sequential behavior feedback and the positive change in four preservice teachers' day-to-day teaching practices in challenging situational contexts, and (b) the relationship between changes in teacher practices and positive changes in the behavioral practices of gymnasium pupils. Sequential behavior feedback was also socially validated by the undergraduate participants and Professional Development School teacher supervisors in the study.

Discussions on Some Educational Issues. Research Report 30.

ERIC Educational Resources Information Center

Kansanen, Pertti, Ed.

Educational issues in Finland and Sweden are addressed in the following papers: (1) "Teacher Training and the Official Teacher's Role" (Karl-Georg Ahlstrom and Maud Johnsson); (2) "Evaluation of Coercive Elements in Education" (Timo Airaksinen); (3) "Philosophy from the Viewpoint of Education" (Pertti Kansanen); (4)…

Atomization methods for forming magnet powders

DOEpatents

Sellers, Charles H.; Branagan, Daniel J.; Hyde, Timothy A.

2000-01-01

The invention encompasses methods of utilizing atomization, methods for forming magnet powders, methods for forming magnets, and methods for forming bonded magnets. The invention further encompasses methods for simulating atomization conditions. In one aspect, the invention includes an atomization method for forming a magnet powder comprising: a) forming a melt comprising R.sub.2.1 Q.sub.13.9 B.sub.1, Z and X, wherein R is a rare earth element; X is an element selected from the group consisting of carbon, nitrogen, oxygen and mixtures thereof; Q is an element selected from the group consisting of Fe, Co and mixtures thereof; and Z is an element selected from the group consisting of Ti, Zr, Hf and mixtures thereof; b) atomizing the melt to form generally spherical alloy powder granules having an internal structure comprising at least one of a substantially amorphous phase or a substantially nanocrystalline phase; and c) heat treating the alloy powder to increase an energy product of the alloy powder; after the heat treatment, the alloy powder comprising an energy product of at least 10 MGOe. In another aspect, the invention includes a magnet comprising R, Q, B, Z and X, wherein R is a rare earth element; X is an element selected from the group consisting of carbon, nitrogen, oxygen and mixtures thereof; Q is an element selected from the group consisting of Fe, Co and mixtures thereof; and Z is an element selected from the group consisting of Ti, Zr, Hf and mixtures thereof; the magnet comprising an internal structure comprising R.sub.2.1 Q.sub.13.9 B.sub.1.

[Effect of atmospheric CO2 concentration and nitrogen application level on absorption and transportation of nutrient elements in oilseed rape].

PubMed

Wang, Wen-ming; Zhang, Zhen-hua; Song, Hai-xing; Liu, Qiang; Rong, Xiang-min; Guan, Chun-yun; Zeng, Jing; Yuan, Dan

2015-07-01

Effect of elevated atmospheric-CO2 (780 µmol . mol-1) on the absorption and transportation of secondary nutrient elements (calcium, magnesium, sulphur) and micronutrient elements (iron, manganese, zinc, molybdenum and boron) in oilseed rape at the stem elongation stage were studied by greenhouse simulated method. Compared with the ambient CO2 condition, the content of Zn in stem was increased and the contents of other nutrient elements were decreased under the elevated atmospheric-CO2 with no nitrogen (N) application; the contents of Ca, S, B and Zn were increased, and the contents of Mg, Mn, Mo and Fe were decreased under the elevated atmospheric CO2 with N application (0.2 g N . kg-1 soil); except the content of Mo in leaf was increased, the contents of other nutrient elements were decreased under the elevated atmospheric-CO2 with two levels of N application. Compared with the ambient CO2 condition, the amounts of Ca and S relative to the total amount of secondary nutrient elements in stem and the amounts of B and Zn relative to the total amount of micronutrient elements in stem were increased under the elevated-CO2 treatment with both levels of N application, and the corresponding values of Mg, Fe, Mn and Mo were decreased; no-N application treatment increased the proportion of Ca distributed into the leaves, and the proportion of Mg distributed into leaves was increased by the normal-N application level; the proportions of Mn, Zn and Mo distributed into the leaves were increased at both N application levels. Without N application, the elevation of atmospheric CO2 increased the transport coefficients of SFe, Mo and SS,B, but decreased the transport coefficients of SMg,Fe, SMg, Mn and SS,Fe, indicating the proportions of Mo, S transported into the upper part of plant tissues was higher than that of Fe, and the corresponding value of B was higher than that observed for S, the corresponding value of Mg was higher than that of Fe and Mn. Under normal-N application, the elevation of atmospheric CO2 increased the transport coefficients of SMg,Fe, SMg,Mn and SS,B, but decreased the transport coefficients of SCa, Mg, SFe,Mo and SS,Fe indicating the proportions of Fe, Mn and Ca transported into the upper part of plant tissues was higher than that of Mg; the corresponding value of B was higher than that observed for S, the corresponding value of Fe was higher than that of Mo, and the corresponding value of S was higher than that of Fe.

Materials and methods for the separation of oxygen from air

DOEpatents

MacKay, Richard; Schwartz, Michael; Sammells, Anthony F.

2003-07-15

Metal oxides particularly useful for the manufacture of catalytic membranes for gas-phase oxygen separation processes having the formula: O.sub.5+z where: x and x' are greater than 0; y and y' are greater than 0; x+x' is equal to 2; y+y' is less than or equal to 2; z is a number that makes the metal oxide charge neutral; A is an element selected from the lanthanide elements; A' is an element selected from Be, Mg, Ca, Sr, Ba and Ra; A" is an element selected from the f block lanthanides, Be, Mg, Ca, Sr, Ba and Ra; B is an element selected from the group consisting of Al, Ga, In or mixtures thereof and B" is Co or Mg, with the exception that when B" is Mg, A' and A" are not Mg. The metal oxides are useful for preparation of dense membranes which may be formed from dense thin films of the mixed metal oxide on a porous metal oxide element. The invention also provides methods and catalytic reactors for oxygen separation and oxygen enrichment of oxygen deficient gases which employ mixed conducting metal oxides of the above formula.

Fourier transform emission spectra and deperturbation analysis of the A2Π - X2Σ+ and B2Σ+ - X2Σ+ electronic transitions of ZnH

NASA Astrophysics Data System (ADS)

Abbasi, Mahdi; Shayesteh, Alireza

2017-10-01

A discharge-furnace emission source was used to generate the A2Π → X2Σ+ and B2Σ+ → X2Σ+ spectra of ZnH radical. High resolution emission spectra were recorded with a Fourier transform spectrometer, and several bands have been assigned for the 64ZnH major isotopologue. The data span the v″ = 0-6 levels of the X2Σ+ ground state, the v‧ = 0-3 levels of the A2Π state, and the v‧ = 0-2 levels of the B2Σ+ state, extending to high rotational quantum numbers near and above the dissociation asymptote of the ground state. Large local perturbations were observed in the A2Π and B2Σ+ electronic states, and a deperturbation analysis was carried out using a single Hamiltonian matrix that includes 2Π and 2Σ+ matrix elements, as well as off-diagonal elements coupling vibrational levels of the two electronic states. Band constants and Dunham coefficients were obtained for the A2Π and B2Σ+ excited states by least-squares-fitting of all the experimental data. The equilibrium vibrational constants ωe and ωexe have been determined to be 1907.528(4) and 38.674(2) cm-1, respectively, for the A2Π state, and 1021.135(94) and 17.725(80) cm-1, for the B2Σ+ state, and the equilibrium Zn-H distances (re) are 1.511662(2) Å and 2.26805(7) Å for the A2Π and B2Σ+ states, respectively. The RKR potential curves were constructed for the A2Π and B2Σ+ states, and vibrational radial overlap integrals were computed. The off-diagonal matrix elements coupling the electronic wavefunctions of the A2Π and B2Σ+ states, i.e., a+ and b, were determined to be 228 ± 3 cm-1 and 0.73 ± 0.01, respectively, for the ZnH molecule.

Achieving Adaptability through Inquiry Based Learning

DTIC Science & Technology

2010-06-01

BLACK, Ph.D. MICHELLE SAMS, Ph.D. Research Program Manager Director Training and Leader Development Division Technical review by Marisa...Learning 5a. CONTRACT OR GRANT NUMBER 5b. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) Thomas M. Duffy (Indiana University) and Pamela...ORGANIZATION NAME( S ) AND ADDRESS(ES) School of Education Army Management Staff College Indiana University 5500 21st Street 201

ICT Use: Educational Technology and Library and Information Science Students' Perspectives--An Exploratory Study

ERIC Educational Resources Information Center

Aharony, Noa; Shonfeld, Miri

2015-01-01

This study seeks to explore what factors influence students' ICT use and web technology competence. The objectives of this study are the following: (a) To what extent do certain elements of Rogers' (2003) Diffusion of Innovations Theory (DOI) explain students' ICT use, (b) To what extent do personality characteristics derived from the Big Five…

Mapping the Future: Young People and Career Guidance.

ERIC Educational Resources Information Center

St. John-Brooks, Caroline

This report examines the strengths and weaknesses of educational and career guidance in seven Organisation for Economic Development (OECD) countries. Chapter 1 defines educational and career guidance as embracing three key elements: educational, career, and personal/social guidance. Described in chapter 2 is the role of educational and career…

Jam Resistant Communications Systems Techniques

DTIC Science & Technology

1982-12-01

ina rayo iteeet -- :."-,(constraint elements plus two resolution elements). •j, r,2 -- ’:." ~d c =0 .4 3 ),, dr l :3 .2X , dr 2 4 5 X @d -900 , s :33...E.K. Walton (Section VIII), and Dr. I.J. Gupta (Sections IX and X ). Mr. R.C. Taylor and R.W. Evans made significant contributions to all experimental...IN THE SAME CUT 190 E. CONCLUSIONS 200 F. REFERENCES 00 SECTION X ELEMENT PLACEMENT FOR ADAPTIVE ANTENNA ARRAYS 201 A. INTRODUCTION 201 B. THE ELEMENT

Fission-Fusion Adaptivity in Finite Elements for Nonlinear Dynamics of Shells

DTIC Science & Technology

1988-11-30

where mesh refinement will prove useful. In fact, the deviation of a bilinear element from a smooth shell midsurface can be related to the angle between...comparisons with nonadaptive meshes. Conclusions and further discussions are given in Section 6. -5- 2. FINITE ELEMENT FORMULATION The shape of the midsurface ...8217 22 , and e3 is defined so that e, and e2 are tangent to the midsurface and rotate with the element; 2. for each node, a triad b i is defined so that

Trace and Major Element Chemistry Across the Cretaceous/Tertiary Boundary at Stevns Klint

NASA Astrophysics Data System (ADS)

Graup, G.; Spettel, B.

1992-07-01

INAA measurements of samples obtained by high-resolution stratigraphy on a mm scale reveal considerable variations in element concentrations across the boundary with their respective maxima stratified in distinct sublayers (Graup et al., 1992). These results suggest that measurements of bulk boundary samples a few cm thick may be inappropriate as concentration variations and element ratios would be leveled out pretending a single geochemical signal. Having investigated a sample comprising sublayers B, C, and D (Fig. 1), Alvarez et al.(1980) acknowledge that "no information is available on the chemical variations within the boundary." This kind of information is given below and shown in Fig. 1 (sublayers A and B are drafted in double scale). From the main lithologic characteristics of Maastrichtian to Paleocene sediments (Schmitz, 1988; Graup et al., 1992) it is readily deduced that Eh and pH conditions in the marine environment changed from oxic-mildly alkaline with normal carbonate sedimentation (Q-M) to anoxic-(mildly) acid with deposition of pyrite spherules (A3), organic material, and clay minerals in the Fish Clay (A-D), followed by a restoration of oxic-alkaline conditions depositing the Cerithium limestone (E- I). The element distribution across the boundary obviously mirrors these alternating environmental conditions: compounds soluble under acid and reducing conditions like Ca-carbonate and Mn are strongly depleted in the Fish Clay (Fig. 1A), whereas compounds stable and insoluble under these conditions are highly enriched (Fig. 1B). The opposite holds true for the calcareous sediments. Across the boundary, enhanced element concentrations are not evenly distributed but appear to be stratified with maximum concentrations in three distinct sublayers for the following elements: (1) A1 (hard clay): peak concentrations for REE (La 72 ppm) and U (45.5 ppm) as compared to 13 ppm La and 2 ppm U in sublayer A2 immediately above. (2) A3 (pyrite spherules): peak concentrations for Fe, Co, Ni, Au, and all chalcophiles. The trace elements correlate well with Fe across the boundary. (3) B (organic-rich marl): peak concentrations for Ir (87.6 ppb), Re (96 ppb, but 113 ppb in C), and organic carbon (2.3%). Ir correlates well with organic carbon (data from Schmitz, 1988), to a lesser extent with Re, and, possibly, Os, but is not correlated with Ni, Co or Au (Graup et al., 1992). Despite large variations in absolute concentrations and, therefore, also of ratios for elements with differing chemical behaviour, there are some pairs of chemically closely related elements (siderophiles as well as chalco- and lithophiles), the ratios of which remain fairly constant over the whole boundary range. Examples shown in Fig. 1A: Ni/Co (average 7.6/std.dev. 1.2) and La/Yb (12.9/2.4). Although Eh,pH conditions vary widely, these elements are not fractionated from each other because of their closely similar geochemical behaviour. The high concentrations of Ir, Ni, and chalcophile elements making up the K/T geochemical anomaly should be indicative of an external component added to the marine environment. The elements introduced were subsequently precipitated according to their chemical properties and changing Eh,pH conditions resulting in stratification of peak concentrations. The constancy of certain element ratios indicates an extended period of availability for this external component. REFERENCES: Alvarez L.W., Alvarez W., Asaro F., and Michel H.V. (1980) Science 208, 1095-1108. Graup G., Palme H., and Spettel B. (1992) Lunar Planet. Sci.(abstract) 23, 445. Schmitz B. (1988) Geology 16, 1068-1072.

CFD Simulation on the J-2X Engine Exhaust in the Center-Body Diffuser and Spray Chamber at the B-2 Facility

NASA Technical Reports Server (NTRS)

Wang, Xiao-Yen; Wey, Thomas; Buehrle, Robert

2009-01-01

A computational fluid dynamic (CFD) code is used to simulate the J-2X engine exhaust in the center-body diffuser and spray chamber at the Spacecraft Propulsion Facility (B-2). The CFD code is named as the space-time conservation element and solution element (CESE) Euler solver and is very robust at shock capturing. The CESE results are compared with independent analysis results obtained by using the National Combustion Code (NCC) and show excellent agreement.

Isolation and Characterization of Strains CVO and FWKO B, Two Novel Nitrate-Reducing, Sulfide-Oxidizing Bacteria Isolated from Oil Field Brine

PubMed Central

Gevertz, Diane; Telang, Anita J.; Voordouw, Gerrit; Jenneman, Gary E.

2000-01-01

Bacterial strains CVO and FWKO B were isolated from produced brine at the Coleville oil field in Saskatchewan, Canada. Both strains are obligate chemolithotrophs, with hydrogen, formate, and sulfide serving as the only known energy sources for FWKO B, whereas sulfide and elemental sulfur are the only known electron donors for CVO. Neither strain uses thiosulfate as an energy source. Both strains are microaerophiles (1% O2). In addition, CVO grows by denitrification of nitrate or nitrite whereas FWKO B reduces nitrate only to nitrite. Elemental sulfur is the sole product of sulfide oxidation by FWKO B, while CVO produces either elemental sulfur or sulfate, depending on the initial concentration of sulfide. Both strains are capable of growth under strictly autotrophic conditions, but CVO uses acetate as well as CO2 as its sole carbon source. Neither strain reduces sulfate; however, FWKO B reduces sulfur and displays chemolithoautotrophic growth in the presence of elemental sulfur, hydrogen, and CO2. Both strains grow at temperatures between 5 and 40°C. CVO is capable of growth at NaCl concentrations as high as 7%. The present 16s rRNA analysis suggests that both strains are members of the epsilon subdivision of the division Proteobacteria, with CVO most closely related to Thiomicrospira denitrifcans and FWKO B most closely related to members of the genus Arcobacter. The isolation of these two novel chemolithotrophic sulfur bacteria from oil field brine suggests the presence of a subterranean sulfur cycle driven entirely by hydrogen, carbon dioxide, and nitrate. PMID:10831429

Strategies for Improving Achievement within Diversity.

ERIC Educational Resources Information Center

Thomson, Scott D.

Understanding students' learning styles is one of the first steps to providing an effective education. Four elements must be present in schools for mastery of content to occur. These four elements operate in sequence and each supports those that follow. The elements are (1) diagnosis of student traits and skills, (2) development of specific…

19 CFR 149.3 - Data elements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 2 2012-04-01 2012-04-01 false Data elements. 149.3 Section 149.3 Customs Duties... (CONTINUED) IMPORTER SECURITY FILING § 149.3 Data elements. (a) Shipments intended to be entered into the... provided for in paragraph (b) of this section, the following elements must be provided for each good listed...

19 CFR 149.3 - Data elements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 2 2014-04-01 2014-04-01 false Data elements. 149.3 Section 149.3 Customs Duties... (CONTINUED) IMPORTER SECURITY FILING § 149.3 Data elements. (a) Shipments intended to be entered into the... provided for in paragraph (b) of this section, the following elements must be provided for each good listed...

19 CFR 149.3 - Data elements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 2 2013-04-01 2013-04-01 false Data elements. 149.3 Section 149.3 Customs Duties... (CONTINUED) IMPORTER SECURITY FILING § 149.3 Data elements. (a) Shipments intended to be entered into the... provided for in paragraph (b) of this section, the following elements must be provided for each good listed...

Suppressive effects of RXR agonist PA024 on adrenal CYP11B2 expression, aldosterone secretion and blood pressure.

PubMed

Suzuki, Dai; Saito-Hakoda, Akiko; Ito, Ryo; Shimizu, Kyoko; Parvin, Rehana; Shimada, Hiroki; Noro, Erika; Suzuki, Susumu; Fujiwara, Ikuma; Kagechika, Hiroyuki; Rainey, William E; Kure, Shigeo; Ito, Sadayoshi; Yokoyama, Atsushi; Sugawara, Akira

2017-01-01

The effects of retinoids on adrenal aldosterone synthase gene (CYP11B2) expression and aldosterone secretion are still unknown. We therefore examined the effects of nuclear retinoid X receptor (RXR) pan-agonist PA024 on CYP11B2 expression, aldosterone secretion and blood pressure, to elucidate its potential as a novel anti-hypertensive drug. We demonstrated that PA024 significantly suppressed angiotensin II (Ang II)-induced CYP11B2 mRNA expression, promoter activity and aldosterone secretion in human adrenocortical H295R cells. Human CYP11B2 promoter functional analyses using its deletion and point mutants indicated that the suppression of CYP11B2 promoter activity by PA024 was in the region from -1521 (full length) to -106 including the NBRE-1 and the Ad5 elements, and the Ad5 element may be mainly involved in the PA024-mediated suppression. PA024 also significantly suppressed the Ang II-induced mRNA expression of transcription factors NURR1 and NGFIB that bind to and activate the Ad5 element. NURR1 overexpression demonstrated that the decrease of NURR1 expression may contribute to the PA024-mediated suppression of CYP11B2 transcription. PA024 also suppressed the Ang II-induced mRNA expression of StAR, HSD3β2 and CYP21A2, a steroidogenic enzyme group involved in aldosterone biosynthesis. Additionally, the PA024-mediated CYP11B2 transcription suppression was shown to be exerted via RXRα. Moreover, the combination of PPARγ agonist pioglitazone and PA024 caused synergistic suppressive effects on CYP11B2 mRNA expression. Finally, PA024 treatment significantly lowered both the systolic and diastolic blood pressure in Tsukuba hypertensive mice (hRN8-12 x hAG2-5). Thus, RXR pan-agonist PA024 may be a candidate anti-hypertensive drugs that acts via the suppression of aldosterone synthesis and secretion.

Role of PTP1B in HER2 Signaling in Breast Cancer

DTIC Science & Technology

2011-10-01

AD_________________ Award Number: W81XWH-10-1-1005 TITLE: Role of PTP1B in HER2 Signaling in...AND SUBTITLE 5a. CONTRACT NUMBER Role of PTP1B in HER2 Signaling in Breast Cancer 5b. GRANT NUMBER W81XWH-10-1-1005 5c. PROGRAM ELEMENT...pathways. Recent reports have shown that Protein Tyrosine Phosphatase 1B ( PTP1B ) plays a positive role in ErbB2-induced breast cancer in vitroand

Transient Inhibition of FGFR2b-Ligands Signaling Leads to Irreversible Loss of Cellular β-Catenin Organization and Signaling in AER during Mouse Limb Development

PubMed Central

Tabatabai, Reza; Baptista, Sheryl; Tiozzo, Caterina; Carraro, Gianni; Wheeler, Matthew; Barreto, Guillermo; Braun, Thomas; Li, Xiaokun; Hajihosseini, Mohammad K.; Bellusci, Saverio

2013-01-01

The vertebrate limbs develop through coordinated series of inductive, growth and patterning events. Fibroblast Growth Factor receptor 2b (FGFR2b) signaling controls the induction of the Apical Ectodermal Ridge (AER) but its putative roles in limb outgrowth and patterning, as well as in AER morphology and cell behavior have remained unclear. We have investigated these roles through graded and reversible expression of soluble dominant-negative FGFR2b molecules at various times during mouse limb development, using a doxycycline/transactivator/tet(O)-responsive system. Transient attenuation (≤24 hours) of FGFR2b-ligands signaling at E8.5, prior to limb bud induction, leads mostly to the loss or truncation of proximal skeletal elements with less severe impact on distal elements. Attenuation from E9.5 onwards, however, has an irreversible effect on the stability of the AER, resulting in a progressive loss of distal limb skeletal elements. The primary consequences of FGFR2b-ligands attenuation is a transient loss of cell adhesion and down-regulation of P63, β1-integrin and E-cadherin, and a permanent loss of cellular β-catenin organization and WNT signaling within the AER. Combined, these effects lead to the progressive transformation of the AER cells from pluristratified to squamous epithelial-like cells within 24 hours of doxycycline administration. These findings show that FGFR2b-ligands signaling has critical stage-specific roles in maintaining the AER during limb development. PMID:24167544

Characteristics of effective classroom teachers as identified by students and professionals: a qualitative study.

PubMed

Jahangiri, Leila; Mucciolo, Thomas W

2008-04-01

This qualitative research study identified criteria for teacher quality preferences as perceived by current and past students. A two-question, open-ended survey asking what qualities learners liked most and least in a teacher/presenter was given to two groups: students (Group A) from medicine, dentistry, and related residency programs; and dentists and physicians (Group B) who had graduated at least three years previously and who attended a minimum of two days of continuing education courses in lecture format each year. A total of 300 subjects provided 2,295 written responses. Descriptive words within the responses were coded and grouped according to similar relationships, resulting in the emergence of twenty-one defined categories that were further refined into three core categories: personality, process, and performance. Results showed that the two groups appear to have different preferences in teacher/presenter characteristics. For Group A (students), the categories of content design, content organization, and content development were at the forefront of their preferences. Group B (professionals) overwhelmingly favored elements of speaker self-confidence and expertise. Both groups highly valued expertise and speaking style. These findings can be used to develop curriculum, enhance faculty members' teaching skills, and plan continuing education programs.

Opportunities in ESSA for Improving Early Education. Education Leaders Report. Volume 2, No. 3

ERIC Educational Resources Information Center

Dichter, Harriet

2016-01-01

For the first time, the nation's most important federal education law, the Every Student Succeeds Act (ESSA), prominently features early childhood education. State and local leaders now have ample flexibility and opportunity to focus on early education as a foundational element of ESSA while advancing their state's vision and goals for early…

Elemental abundance analyses with DAO spectrograms: XXX. The middle B through early A stars ξ2 Ceti (B9 III), 21 Aquilae (B8 II-III), ι Aquilae (B5 III), and ι Delphini (A2V)

NASA Astrophysics Data System (ADS)

Adelman, S. J.; Westbrook, P. C.; Gulliver, A. F.

2010-04-01

This series of high quality elemental abundance analyses of mostly main-sequence band normal and peculiar B, A, and F stars defines their properties and provides data for the comparison with the analyses of somewhat similar stars and with theoretical predictions. Most use high dispersion and high S/N (≥ 200) spectrograms obtained with CCD detectors at the long camera of the Coudé spectrograph of the 1.22-m Dominion Astrophysical Observatory telescope. Here we reanalyze 21 Aql with better quality spectra and increase the number of stars consistently analyzed in the spectral range B5 to A2 by analyzing three new stars for this series. In the early A stars the normal and non-mCP stars have abundances with overlapping ranges. But more stars are needed especially in the B5 to B9 range. ξ2 Cet on average has a solar composition with a few abundances outside the solar range while both 21 Aql and ι Aql have abundances marginally less than solar. The abundances of ι Del are greater than solar with a few elements such as Ca being less than solar. It is an Am star. Table 3 is only available in electronic form at the CDS via http://cdsarc.u-strasbg.fr/ftp/cats/J/other/AN/331/378

$$B^0_{(s)}$$-mixing matrix elements from lattice QCD for the Standard Model and beyond

DOE PAGES

Bazavov, A.; Bernard, C.; Bouchard, C. M.; ...

2016-06-28

We calculate—for the first time in three-flavor lattice QCD—the hadronic matrix elements of all five local operators that contribute to neutral B 0- and B s-meson mixing in and beyond the Standard Model. We present a complete error budget for each matrix element and also provide the full set of correlations among the matrix elements. We also present the corresponding bag parameters and their correlations, as well as specific combinations of the mixing matrix elements that enter the expression for the neutral B-meson width difference. We obtain the most precise determination to date of the SU(3)-breaking ratio ξ=1.206(18)(6), where themore » second error stems from the omission of charm-sea quarks, while the first encompasses all other uncertainties. The threefold reduction in total uncertainty, relative to the 2013 Flavor Lattice Averaging Group results, tightens the constraint from B mixing on the Cabibbo-Kobayashi-Maskawa (CKM) unitarity triangle. Our calculation employs gauge-field ensembles generated by the MILC Collaboration with four lattice spacings and pion masses close to the physical value. We use the asqtad-improved staggered action for the light-valence quarks and the Fermilab method for the bottom quark. We use heavy-light meson chiral perturbation theory modified to include lattice-spacing effects to extrapolate the five matrix elements to the physical point. We combine our results with experimental measurements of the neutral B-meson oscillation frequencies to determine the CKM matrix elements |V td| = 8.00(34)(8)×10 -3, |V ts| = 39.0(1.2)(0.4)×10 -3, and |V td/V ts| = 0.2052(31)(10), which differ from CKM-unitarity expectations by about 2σ. In addition, these results and others from flavor-changing-neutral currents point towards an emerging tension between weak processes that are mediated at the loop and tree levels.« less

Spacesuit guidebook

NASA Technical Reports Server (NTRS)

1991-01-01

This guidebook is designed to supplement the Spacesuit wall chart (WAL-114) published by the Education Affairs Division, January 1990. The wall chart depicts Astronaut Bruce McCandless on his historic first untethered spacewalk using the manned maneuvering unit. He flew on Shuttle mission 41-B, and ventured 100 meters for the Shuttle's cargo bay and returned safely. This guidebook explains in depth the elements depicted on the wall chart in see-through and cut-away perspectives. Together the wall chart and guidebook show as well as explain the inside workings of the spacesuit and its various components. Forty separate elements are identified with an accompanying numerical legend. Those elements are further explained in this guidebook along with their functions and how they work in relation to other elements. Additional chapters discuss essential components of the spacesuit such as the primary life support system and the manned maneuvering unit, and the method for donning the spacesuit.

Experimental validation of boundary element methods for noise prediction

NASA Technical Reports Server (NTRS)

Seybert, A. F.; Oswald, Fred B.

1992-01-01

Experimental validation of methods to predict radiated noise is presented. A combined finite element and boundary element model was used to predict the vibration and noise of a rectangular box excited by a mechanical shaker. The predicted noise was compared to sound power measured by the acoustic intensity method. Inaccuracies in the finite element model shifted the resonance frequencies by about 5 percent. The predicted and measured sound power levels agree within about 2.5 dB. In a second experiment, measured vibration data was used with a boundary element model to predict noise radiation from the top of an operating gearbox. The predicted and measured sound power for the gearbox agree within about 3 dB.

Not Your Father's Web Site: Corporate Sites Emerge as New Content Innovators.

ERIC Educational Resources Information Center

O'Leary, Mick

2002-01-01

New economy corporate Web sites have pioneered exciting techniques-rich media, interactivity, personalization, community, and integration of much third-party content. Discusses business-to-business (B2B) Web commerce, with examples of several B2B corporate sites; portal and content elements of these sites; and corporate content outlooks. (AEF)

Insights into selenite reduction and biogenesis of elemental selenium nanoparticles by two environmental isolates of Burkholderia fungorum.

PubMed

Khoei, Nazanin Seyed; Lampis, Silvia; Zonaro, Emanuele; Yrjälä, Kim; Bernardi, Paolo; Vallini, Giovanni

2017-01-25

Microorganisms capable of transforming toxic selenium oxyanions into non-toxic elemental selenium (Se°) may be considered as biocatalysts for the production of selenium nanoparticles (SeNPs), eventually exploitable in different biotechnological applications. Two Burkholderia fungorum strains (B. fungorum DBT1 and B. fungorum 95) were monitored during their growth for both capacity and efficiency of selenite (SeO 3 2- ) reduction and elemental selenium formation. Both strains are environmental isolates in origin: B. fungorum DBT1 was previously isolated from an oil refinery drainage, while B. fungorum 95 has been enriched from inner tissues of hybrid poplars grown in a soil contaminated by polycyclic aromatic hydrocarbons. Our results showed that B. fungorum DBT1 is able to reduce 0.5mM SeO 3 2- to Se° when cultured aerobically in liquid medium at 27°C, while B. fungorum 95 can reduce more than 1mM SeO 3 2- to Se° within 96h under the same growth conditions, with the appearance of SeNPs in cultures of both bacterial strains. Biogenic SeNPs were spherical, with pH-dependent charge and an average hydrodynamic diameter of 170nm and 200nm depending on whether they were produced by B. fungorum 95 or B. fungorum DBT1, respectively. Electron microscopy analyses evidenced that Se nanoparticles occurred intracellularly and extracellularly. The mechanism of SeNPs formation can be tentatively attributed to cytoplasmic enzymatic activation mediated by electron donors. Biogenic nanoparticles were then probably released outside the bacterial cells as a consequence of a secretory process or cell lysis. Nevertheless, formation of elemental selenium nanoparticles under aerobic conditions by B. fungorum DBT1 and B. fungorum 95 is likely due to intracellular reduction mechanisms. Biomedical and other high tech sectors might exploit these biogenic nanoparticles in the near future, once fully characterized and tested for their multiple properties. Copyright © 2016 Elsevier B.V. All rights reserved.

Implementation of Nonhomogeneous Dirichlet Boundary Conditions in the p- Version of the Finite Element Method

DTIC Science & Technology

1988-09-01

Institute for Physical Science and Teennology rUniversity of Maryland o College Park, MD 20742 B. Gix) Engineering Mechanics Research Corporation Troy...OF THE FINITE ELEMENT METHOD by Ivo Babuska Institute for Physical Science and Technology University of Maryland College Park, MD 20742 B. Guo 2...2Research partially supported by the National Science Foundation under Grant DMS-85-16191 during the stay at the Institute for Physical Science and

A genome survey sequencing of the Java mouse deer (Tragulus javanicus) adds new aspects to the evolution of lineage specific retrotransposons in Ruminantia (Cetartiodactyla).

PubMed

Gallus, S; Kumar, V; Bertelsen, M F; Janke, A; Nilsson, M A

2015-10-25

Ruminantia, the ruminating, hoofed mammals (cow, deer, giraffe and allies) are an unranked artiodactylan clade. Around 50-60 million years ago the BovB retrotransposon entered the ancestral ruminantian genome through horizontal gene transfer. A survey genome screen using 454-pyrosequencing of the Java mouse deer (Tragulus javanicus) and the lesser kudu (Tragelaphus imberbis) was done to investigate and to compare the landscape of transposable elements within Ruminantia. The family Tragulidae (mouse deer) is the only representative of Tragulina and phylogenetically important, because it represents the earliest divergence in Ruminantia. The data analyses show that, relative to other ruminantian species, the lesser kudu genome has seen an expansion of BovB Long INterspersed Elements (LINEs) and BovB related Short INterspersed Elements (SINEs) like BOVA2. In comparison the genome of Java mouse deer has fewer BovB elements than other ruminants, especially Bovinae, and has in addition a novel CHR-3 SINE most likely propagated by LINE-1. By contrast the other ruminants have low amounts of CHR SINEs but high numbers of actively propagating BovB-derived and BovB-propagated SINEs. The survey sequencing data suggest that the transposable element landscape in mouse deer (Tragulina) is unique among Ruminantia, suggesting a lineage specific evolutionary trajectory that does not involve BovB mediated retrotransposition. This shows that the genomic landscape of mobile genetic elements can rapidly change in any lineage. Copyright © 2015 Elsevier B.V. All rights reserved.

34 CFR Appendix C to Part 300 - National Instructional Materials Accessibility Standard (NIMAS)

Code of Federal Regulations, 2011 CFR

2011-07-01

.... Using educationLevel obviates the need for a separate field for gradeRange since dc elements can repeat... 34 Education 2 2011-07-01 2010-07-01 true National Instructional Materials Accessibility Standard (NIMAS) C Appendix C to Part 300 Education Regulations of the Offices of the Department of Education...

A THEORETICAL MODEL FOR RESEARCH IN EDUCATION.

ERIC Educational Resources Information Center

ARMSTRONG, JENNY R.

THE FAILURE OF EDUCATIONAL RESEARCH TO CONTRIBUTE LARGE CONSISTENT BODIES OF KNOWLEDGE ABOUT THE EDUCATIONAL PROCESS HAS BEEN DUE TO FIVE MAJOR FACTORS--(1) FAULTY EXPERIMENTAL DESIGN, (2) FAILURE TO CONSIDER ALL OF THE MAJOR INPUT ELEMENTS OF THE EDUCATIONAL PROCESS, (3) FAILURE TO MAKE MEANINGFUL COMPARISONS (FOR EXAMPLE THE CONTROL GROUP IS NOT…

Training Frontline Staff. Supported Education: A Promising Practice. Evidence-Based Practices KIT (Knowledge Informing Transformation)

ERIC Educational Resources Information Center

Unger, Karen V.

2011-01-01

This four-part workbook will help program leaders teach education specialists the principles, processes, and skills necessary to deliver effective Supported Education services. The workbook includes the following: (1) Basic elements and practice principles of Supported Education; (2) Knowledge and skills to help consumers make informed choices…

Anomalous temperature dependence of yield stress and work hardening coefficient of B2-stabilized NiTi alloys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hosoda, Hideki; Mishima, Yoshinao; Suzuki, Tomoo

Yield stress and work hardening coefficient of B2-stabilized NiTi alloys are investigated using compression tests. Compositions of NiTi alloys are based on Ni-49mol.%Ti, to which Cr, Co and Al are chosen as ternary elements which reduce martensitic transformation temperatures of the B2 phase. Mechanical tests are carried out in liquid nitrogen at 77 K, air at room temperature (R.T.) and in an argon atmosphere between 473 K and 873 K. Only at 77 K, some alloys show characteristic stress-strain curves which indicate stress induced martensitic transformation (SIMT), but the others do not. Work hardening coefficient is found to be betweenmore » 2 and 11GPa in all the test temperature range. The values are extremely high compared with Young`s modulus of B2 NiTi. Yield stress and work hardening coefficient increase with test temperature between R.T. and about 650 K in most alloys. The anomalous temperature dependence of mechanical properties is not related to SIMT but to precipitation hardening and/or anomalous dislocation motion similar to B2-type CoTi. Solution hardening by adding ternary elements is evaluated to be small for Cr and Co additions, and large for Al addition, depending on difference in atomic size of the ternary element with respect to Ni or Ti.« less

Analysis of Visual Interpretation of Satellite Data

NASA Astrophysics Data System (ADS)

Svatonova, H.

2016-06-01

Millions of people of all ages and expertise are using satellite and aerial data as an important input for their work in many different fields. Satellite data are also gradually finding a new place in education, especially in the fields of geography and in environmental issues. The article presents the results of an extensive research in the area of visual interpretation of image data carried out in the years 2013 - 2015 in the Czech Republic. The research was aimed at comparing the success rate of the interpretation of satellite data in relation to a) the substrates (to the selected colourfulness, the type of depicted landscape or special elements in the landscape) and b) to selected characteristics of users (expertise, gender, age). The results of the research showed that (1) false colour images have a slightly higher percentage of successful interpretation than natural colour images, (2) colourfulness of an element expected or rehearsed by the user (regardless of the real natural colour) increases the success rate of identifying the element (3) experts are faster in interpreting visual data than non-experts, with the same degree of accuracy of solving the task, and (4) men and women are equally successful in the interpretation of visual image data.

Analysis of Instructional Support Elements for an Online, Educational Simulation on Active Listening for Women Graduate Students in Science and Engineering

ERIC Educational Resources Information Center

Bernstein, Bianca L.; Bekki, Jennifer M.; Wilkins, Kerrie G.; Harrison, Caroline J.

2016-01-01

Strong interpersonal communication skills (ICS) are critical for educational and career success, but effective and widely accessible training systems are not available. This paper describes a 2 × 2 × 2 experimental study of an online, educational simulation for practice with the ICS of active listening. The simulation was customized for women…

Design and development of ultra-wideband 3 dB hybrid coupler for Ion cyclotron resonance frequency heating in tokamak.

PubMed

Yadav, Rana Pratap; Kumar, Sunil; Kulkarni, S V

2014-04-01

Design and development of a high power ultra-wideband, 3 dB tandem hybrid coupler is presented and its application in ICRF heating of the tokamak is discussed. In order to achieve the desired frequency band of 38-112 MHz and 200 kW power handling capability, the 3 dB hybrid coupler is developed using two 3-element 8.34 ± 0.2 dB coupled lines sections in tandem. In multi-element coupled lines, junctions are employed for the joining of coupled elements that produce the undesirable reactance called junction discontinuity effect. The effect becomes prominent in the high power multi-element coupled lines for high frequency (HF) and very high frequency(VHF) applications because of larger structural dimensions. Junction discontinuity effect significantly deteriorates coupling and output performance from the theoretical predictions. For the analysis of junction discontinuity effect and its compensation, a theoretical approach has been developed and generalized for n-element coupled lines section. The theory has been applied in the development of the 3 dB hybrid coupler. The fabricated hybrid coupler has been experimentally characterized using vector network analyzer and obtained results are found in good agreement with developed theory.

A Comparison of Prostate Cancer Incidence Between U.S. Air Force Enlisted Aircrew

DTIC Science & Technology

2011-06-30

COL DAVID B. RHODES, RAM Prog Dir COL ROBERT E. CARROLL , Chair FE...PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) Joseph A. Lopez 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING...ORGANIZATION NAME( S ) AND ADDRESS(ES) USAF School of Aerospace Medicine Aerospace Medicine Education/FEEG 2510 Fifth St. Wright-Patterson AFB, OH 45433-7913

25 CFR 47.2 - What definitions apply to terms in this part?

Code of Federal Regulations, 2014 CFR

2014-04-01

... Section 47.2 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION UNIFORM DIRECT FUNDING AND SUPPORT FOR BUREAU-OPERATED SCHOOLS § 47.2 What definitions apply to terms in this part? Act means... Bureau-operated school boards regarding each element of the local educational financial plan and...

25 CFR 47.2 - What definitions apply to terms in this part?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 47.2 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION UNIFORM DIRECT FUNDING AND SUPPORT FOR BUREAU-OPERATED SCHOOLS § 47.2 What definitions apply to terms in this part? Act means... Bureau-operated school boards regarding each element of the local educational financial plan and...

25 CFR 47.2 - What definitions apply to terms in this part?

Code of Federal Regulations, 2011 CFR

2011-04-01

... Section 47.2 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION UNIFORM DIRECT FUNDING AND SUPPORT FOR BUREAU-OPERATED SCHOOLS § 47.2 What definitions apply to terms in this part? Act means... Bureau-operated school boards regarding each element of the local educational financial plan and...

25 CFR 47.2 - What definitions apply to terms in this part?

Code of Federal Regulations, 2010 CFR

2010-04-01

... Section 47.2 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION UNIFORM DIRECT FUNDING AND SUPPORT FOR BUREAU-OPERATED SCHOOLS § 47.2 What definitions apply to terms in this part? Act means... Bureau-operated school boards regarding each element of the local educational financial plan and...

25 CFR 47.2 - What definitions apply to terms in this part?

Code of Federal Regulations, 2013 CFR

2013-04-01

... Section 47.2 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION UNIFORM DIRECT FUNDING AND SUPPORT FOR BUREAU-OPERATED SCHOOLS § 47.2 What definitions apply to terms in this part? Act means... Bureau-operated school boards regarding each element of the local educational financial plan and...

Dual-frequency super harmonic imaging piezoelectric transducers for transrectal ultrasound

NASA Astrophysics Data System (ADS)

Kim, Jinwook; Li, Sibo; Kasoji, Sandeep; Dayton, Paul A.; Jiang, Xiaoning

2015-03-01

In this paper, a 2/14 MHz dual-frequency single-element transducer and a 2/22 MHz sub-array (16/48-elements linear array) transducer were developed for contrast enhanced super-harmonic ultrasound imaging of prostate cancer with the low frequency ultrasound transducer as a transmitter for contrast agent (microbubble) excitation and the high frequency transducer as a receiver for detection of nonlinear responses from microbubbles. The 1-3 piezoelectric composite was used as active materials of the single-element transducers due to its low acoustic impedance and high coupling factor. A high dielectric constant PZT ceramic was used for the sub-array transducer due to its high dielectric property induced relatively low electrical impedance. The possible resonance modes of the active elements were estimated using finite element analysis (FEA). The pulse-echo response, peak-negative pressure and bubble response were tested, followed by in vitro contrast imaging tests using a graphite-gelatin tissue-mimicking phantom. The single-element dual frequency transducer (8 × 4 × 2 mm3) showed a -6 dB fractional bandwidth of 56.5% for the transmitter, and 41.8% for the receiver. A 2 MHz-transmitter (730 μm pitch and 6.5 mm elevation aperture) and a 22 MHz-receiver (240 μm pitch and 1.5 mm aperture) of the sub-array transducer exhibited -6 dB fractional bandwidth of 51.0% and 40.2%, respectively. The peak negative pressure at the far field was about -1.3 MPa with 200 Vpp, 1-cycle 2 MHz burst, which is high enough to excite microbubbles for nonlinear responses. The 7th harmonic responses from micro bubbles were successfully detected in the phantom imaging test showing a contrast-to-tissue ratio (CTR) of 16 dB.

Investigacion Participativa y Gestion de Sistemas Educativos. (Participatory Research and the Management of Educational Systems).

ERIC Educational Resources Information Center

Valle, Victor M.

Elements which, when put in harmony, might generate powerful tools for social change and educational development are (1) the ever present need of the educational systems to evaluate their performance; (2) the universal acceptance of the life-long education concept as a major guideline to design educational programs; (3) the trend toward a…

Thermal barrier coating having high phase stability

DOEpatents

Subramanian, Ramesh

2001-01-01

A device (10) comprising a substrate (22) having a deposited ceramic thermal barrier coating layer (20) characterized by a microstructure having gaps (28) where the thermal barrier coating (20) consists essentially of a pyrochlore crystal structure having a chemical formula consisting essentially of A.sup.n+.sub.2-x B.sup.m+.sub.2+x O.sub.7-y, where A is selected from the group of elements selected from La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, and mixtures thereof; where B is selected from the group of elements selected from Zr, Hf, Ti and mixtures thereof; n and m are the valence of A and B respectively, and for -0.5.ltoreq.x.ltoreq.0.5, ##EQU1## and excluding the following combinations for x=0, y=0: A=La and B=Zr; A=La and B=Hf; A=Gd and B=Hf; and A=Yb and B=Ti.

Lentivirus Vectors Incorporating the Immunoglobulin Heavy Chain Enhancer and Matrix Attachment Regions Provide Position-Independent Expression in B Lymphocytes

PubMed Central

Lutzko, Carolyn; Senadheera, Dinithi; Skelton, Dianne; Petersen, Denise; Kohn, Donald B.

2003-01-01

In the present studies we developed lentivirus vectors with regulated, consistent transgene expression in B lymphocytes by incorporating the immunoglobulin heavy chain enhancer (Eμ) with and without associated matrix attachment regions (EμMAR) into lentivirus vectors. Incorporation of these fragments upstream of phosphoglycerate kinase (PGK) or cytomegalovirus promoters resulted in a two- to threefold increase in enhanced green fluorescent protein (EGFP) mean fluorescence intensity (MFI) in B-lymphoid but not T-lymphoid, myeloid, fibroblast, or carcinoma cell lines. A 1-log increase in EGFP expression was observed in B-lymphoid cells (but not myeloid cells) differentiated from human CD34+ progenitors in vitro transduced with Eμ- and EμMAR-containing lentivectors. Lastly, we evaluated the expression from the EμMAR element in mice 2 to 24 weeks posttransplant with transduced hematopoietic stem cells. In mice receiving vectors with the Eμ and EμMAR elements upstream of the PGK promoter, there was a 2- to 10-fold increase in EGFP expression in B cells (but not other cell types). Evaluation of the coefficient of variation of expression among different cell types demonstrated that consistent, position-independent transgene expression was observed exclusively in B cells transduced with the EμMAR-containing vector and not other cells types or vectors. Proviral genomes with the EμMAR element had increased chromatin accessibility, which likely contributed to the position independence of expression in B lymphocytes. In summary, incorporation of the EμMAR element in lentivirus vectors resulted in enhanced, position-independent expression in primary B lymphocytes. These vectors provide a useful tool for the study of B-lymphocyte biology and the development of gene therapy for disorders affecting B lymphocytes, such as immune deficiencies. PMID:12805432

Effects of Various Shaped Roughness Elements in Two-Dimensional High Reynolds Number Turbulent Boundary Layers

DTIC Science & Technology

2004-08-28

CN u-- 9 0 Cu I4 -M CM 4C -A -A - f +U 0 +. 0. U 0 - 0 00000O00000 INI 040 C.)) U, *7 70 0 C 0 0 0 -’U 000000000 N 0 o, ?’ "b LQA C -A A +, L0 M...Aerodynamics, 28:291-300. Schetz, J.A., (1993), "Boundary Layer Analysis," Prentice-Hall, Inc., A Pearson Education Company, Upper Saddle River, NJ...In pursuit of higher education , he entered the graduate program in the Aerospace and Ocean Engineering Department at Virginia Polytechnic Institute

An active Mitochondrial Complex II Present in Mature Seeds Contains an Embryo-Specific Iron-Sulfur Subunit Regulated by ABA and bZIP53 and Is Involved in Germination and Seedling Establishment.

PubMed

Restovic, Franko; Espinoza-Corral, Roberto; Gómez, Isabel; Vicente-Carbajosa, Jesús; Jordana, Xavier

2017-01-01

Complex II (succinate dehydrogenase) is an essential mitochondrial enzyme involved in both the tricarboxylic acid cycle and the respiratory chain. In Arabidopsis thaliana , its iron-sulfur subunit (SDH2) is encoded by three genes, one of them ( SDH2.3 ) being specifically expressed during seed maturation in the embryo. Here we show that seed SDH2.3 expression is regulated by abscisic acid (ABA) and we define the promoter region (-114 to +49) possessing all the cis -elements necessary and sufficient for high expression in seeds. This region includes between -114 and -32 three ABRE (ABA-responsive) elements and one RY-enhancer like element, and we demonstrate that these elements, although necessary, are not sufficient for seed expression, our results supporting a role for the region encoding the 5' untranslated region (+1 to +49). The SDH2.3 promoter is activated in leaf protoplasts by heterodimers between the basic leucine zipper transcription factors bZIP53 (group S1) and bZIP10 (group C) acting through the ABRE elements, and by the B3 domain transcription factor ABA insensitive 3 (ABI3). The in vivo role of bZIP53 is further supported by decreased SDH2.3 expression in a knockdown bzip53 mutant. By using the protein synthesis inhibitor cycloheximide and sdh2 mutants we have been able to conclusively show that complex II is already present in mature embryos before imbibition, and contains mainly SDH2.3 as iron-sulfur subunit. This complex plays a role during seed germination sensu-stricto since we have previously shown that seeds lacking SDH2.3 show retarded germination and now we demonstrate that low concentrations of thenoyltrifluoroacetone, a complex II inhibitor, also delay germination. Furthermore, complex II inhibitors completely block hypocotyl elongation in the dark and seedling establishment in the light, highlighting an essential role of complex II in the acquisition of photosynthetic competence and the transition from heterotrophy to autotrophy.

RNA-dependent RNA polymerase of hepatitis C virus binds to its coding region RNA stem-loop structure, 5BSL3.2, and its negative strand.

PubMed

Kanamori, Hiroshi; Yuhashi, Kazuhito; Ohnishi, Shin; Koike, Kazuhiko; Kodama, Tatsuhiko

2010-05-01

The hepatitis C virus NS5B RNA-dependent RNA polymerase (RdRp) is a key enzyme involved in viral replication. Interaction between NS5B RdRp and the viral RNA sequence is likely to be an important step in viral RNA replication. The C-terminal half of the NS5B-coding sequence, which contains the important cis-acting replication element, has been identified as an NS5B-binding sequence. In the present study, we confirm the specific binding of NS5B to one of the RNA stem-loop structures in the region, 5BSL3.2. In addition, we show that NS5B binds to the complementary strand of 5BSL3.2 (5BSL3.2N). The bulge structure of 5BSL3.2N was shown to be indispensable for tight binding to NS5B. In vitro RdRp activity was inhibited by 5BSL3.2N, indicating the importance of the RNA element in the polymerization by RdRp. These results suggest the involvement of the RNA stem-loop structure of the negative strand in the replication process.

Elbow stress indices using finite element analysis

NASA Astrophysics Data System (ADS)

Yu, Lixin

Section III of the ASME Boiler and Pressure Vessel Code (the Code) specifies rules for the design of nuclear power plant components. NB-3600 of the Code presents a simplified design method using stress indices---Scalar Coefficients used the modify straight pipe stress equations so that they can be applied to elbows, tees and other piping components. The stress indices of piping components are allowed to be determined both analytically and experimentally. This study concentrates on the determination of B2 stress indices for elbow components using finite element analysis (FEA). First, the previous theoretical, numerical and experimental investigations on elbow behavior were comprehensively reviewed, as was the philosophy behind the use of stress indices. The areas of further research was defined. Then, a comprehensive investigation was carried out to determine how the finite element method should be used to correctly simulate an elbow's structural behavior. This investigation included choice of element type, convergence of mesh density, use of boundary restraint and a reconciliation study between FEA and laboratory experiments or other theoretical formulations in both elastic and elasto-plastic domain. Results from different computer programs were also compared. Reasonably good reconciliation was obtained. Appendix II of the Code describes the experimental method to determine B2 stress indices based on load-deflection curves. This procedure was used to compute the B2 stress indices for various loading modes on one particular elbow configuration. The B2 stress indices thus determined were found to be about half of the value calculated from the Code equation. Then the effect on B2 stress indices of those factors such as internal pressure and flange attachments were studied. Finally, the investigation was extended to other configurations of elbow components. A parametric study was conducted on different elbow sizes and schedules. Regression analysis was then used to obtain a modified coefficient and exponent for the Code equation used to calculate B2 index for elbows.

Just Around the Corner... A Guide for Career Education in the Intermediate Levels.

ERIC Educational Resources Information Center

Arkansas State Dept. of Education, Little Rock. Career Education Section.

This curriculum guide provides examples of activities a teacher at the intermediate level can use for any phase of career education being studied. Activities are listed under each of the eight elements of career education: (1) Self Awareness, (2) Educational Awareness, (3) Career Awareness, (4) Economic Awareness, (5) Decision Making, (6)…

Iran's Implicit Philosophy of Education

ERIC Educational Resources Information Center

Bagheri Noaparast, Khosrow

2018-01-01

This paper aims to extract Iran's philosophy of education from two sources of the constitution and the course of practice in educational institutions. Regarding the first source, it is argued that parallel to the two main threads of the constitution, Iran's main elements of philosophy of education are expected to be derived from; (1) Islam and (2)…

Citizenship and Citizenship Education in a Global Age: Politics, Policies, and Practices in China. Global Studies in Education. Volume 2

ERIC Educational Resources Information Center

Law, Wing-Wah

2011-01-01

This book examines issues of citizenship, citizenship education, and social change in China, exploring the complexity of interactions among global forces, the nation-state, local governments, schools, and individuals--including students--in selecting and identifying with elements of citizenship and citizenship education in a multileveled polity.…

An easy packaging hybrid optical element in grating based WDM application

NASA Astrophysics Data System (ADS)

Lan, Hsiao-Chin; Cheng, Chao-Chia; Wang, Chih-Ming; Chang, Jenq-Yang

2005-08-01

We developed a new optical element which integrates an off-axis diffractive grating and an on-axis refractive lens surface in a prism. With this optical element, the alignment tolerance can be improved by manufacturing technology of the grating based WDM device and is practicable for mass production. An 100-GHz 16-channel DWDM device which includes this optical element has been designed. Ray tracing and beam propagation method (BPM) simulations showed good performance on the insertion loss of 2.91+/-0.53dB and the adjacent cross talk of 58.02dB. The tolerance discussion for this DWDM device shows that this optical element could be practically achieved by either injection molding or the hot embossing method.

26 CFR 1.72-2 - Applicability of section.

Code of Federal Regulations, 2014 CFR

2014-04-01

... more annuity obligations or elements to which section 72 applies are acquired for a single...), such annuity elements shall be considered to comprise a single contract for the purpose of the... in the contract in the case of annuity elements payable to two or more persons, see paragraph (b) of...

26 CFR 1.72-2 - Applicability of section.

Code of Federal Regulations, 2011 CFR

2011-04-01

... more annuity obligations or elements to which section 72 applies are acquired for a single...), such annuity elements shall be considered to comprise a single contract for the purpose of the... in the contract in the case of annuity elements payable to two or more persons, see paragraph (b) of...

26 CFR 1.72-2 - Applicability of section.

Code of Federal Regulations, 2012 CFR

2012-04-01

... more annuity obligations or elements to which section 72 applies are acquired for a single...), such annuity elements shall be considered to comprise a single contract for the purpose of the... in the contract in the case of annuity elements payable to two or more persons, see paragraph (b) of...

26 CFR 1.72-2 - Applicability of section.

Code of Federal Regulations, 2013 CFR

2013-04-01

... more annuity obligations or elements to which section 72 applies are acquired for a single...), such annuity elements shall be considered to comprise a single contract for the purpose of the... in the contract in the case of annuity elements payable to two or more persons, see paragraph (b) of...

Characterizations of the Core-Shell Structured MgB2/CARBON Fiber Synthesis by Rf-Sputtering and Thermal Evaporation

NASA Astrophysics Data System (ADS)

Park, Sung Chang; Lim, Yeong Jin; Lee, Tae-Keun; Kim, Cheol Jin

MgB2/carbon fibers have been synthesized by the combination of RF-sputtering of B and thermal evaporation of Mg, followed by co-evaporation. First, boron layer was deposited by RF-sputtering on the carbon fiber with average diameter of 7.1 μm. Later this coated layer of B was reacted with Mg vapor to transform into MgB2. Since the MgB2 reaction proceed with Mg diffusion into the boron layer, Mg vapor pressure and the diffusion time had to be controlled precisely to secure the complete reaction. Also the deposition rate of each element was controlled separately to obtain stoichiometric MgB2, since Mg was evaporated by thermal heating and B by sputtering system. The sintered B target was magnetron sputtered at the RF-power of ~200 W, which corresponded to the deposition rate of ~3.6 Å/s. With the deposition rate of B fixed, the vapor pressure of Mg was controlled by varying the temperature of tungsten boat with heating element control unit between 100 and 900°C. The MgB2 layers with the thickness of 200-950 nm could be obtained and occasionally MgO appeared as a second phase. Superconducting transition temperatures were measured around ~38 K depending on the deposition condition.

The Decade of Education for Sustainable Development: Challenges and Opportunities in Mexico

ERIC Educational Resources Information Center

Gonzalez-Gaudiano, Edgar

2005-01-01

The international implementation plan for the Decade of Education for Sustainable Development (DESD) identifies four elements for the achievement of sustainable development through education: (1) recognising the challenge; (2) collective responsibility and constructive society; (3) acting with determination; and (4) the indivisibility of human…

Essential Readings in Environmental Education.

ERIC Educational Resources Information Center

Hungerford, Harold R., Ed.; Bluhm, William J., Ed.; Volk, Trudi L., Ed.; Ramsey, John M., Ed.

This book provides 29 readings that provide a detailed overview of those elements that might take environmental education from the intuitive to the valid, to a field where there truly is a defensible, substantive structure. Contents include: (1) "Tensions in Environmental Education: Yesterday, Today, and Tomorrow" (Disinger, John F.); (2) "The…

Ceramic membranes for catalytic membrane reactors with high ionic conductivities and low expansion properties

DOEpatents

Mackay, Richard; Sammells, Anthony F.

2000-01-01

Ceramics of the composition: Ln.sub.x Sr.sub.2-x-y Ca.sub.y B.sub.z M.sub.2-z O.sub.5+.delta. where Ln is an element selected from the fblock lanthanide elements and yttrium or mixtures thereof; B is an element selected from Al, Ga, In or mixtures thereof; M is a d-block transition element of mixtures thereof; 0.01.ltoreq.x.ltoreq.1.0; 0.01.ltoreq.y.ltoreq.0.7; 0.01.ltoreq.z.ltoreq.1.0 and .delta. is a number that varies to maintain charge neutrality are provided. These ceramics are useful in ceramic membranes and exhibit high ionic conductivity, high chemical stability under catalytic membrane reactor conditions and low coefficients of expansion. The materials of the invention are particularly useful in producing synthesis gas.

Electrochemical hydrogen storage alloys and batteries fabricated from Mg containing base alloys

DOEpatents

Ovshinsky, Stanford R.; Fetcenko, Michael A.

1996-01-01

An electrochemical hydrogen storage material comprising: (Base Alloy).sub.a M.sub.b where, Base Alloy is an alloy of Mg and Ni in a ratio of from about 1:2 to about 2:1, preferably 1:1; M represents at least one modifier element chosen from the group consisting of Co, Mn, Al, Fe, Cu, Mo, W, Cr, V, Ti, Zr, Sn, Th, Si, Zn, Li, Cd, Na, Pb, La, Mm, and Ca; b is greater than 0.5, preferably 2.5, atomic percent and less than 30 atomic percent; and a+b=100 atomic percent. Preferably, the at least one modifier is chosen from the group consisting of Co, Mn, Al, Fe, and Cu and the total mass of the at least one modifier element is less than 25 atomic percent of the final composition. Most preferably, the total mass of said at least one modifier element is less than 20 atomic percent of the final composition.

Role of PTP1B in HER2 Signaling in Breast Cancer

DTIC Science & Technology

2012-10-01

AD_________________ Award Number: W81XWH-10-1-1005 TITLE: Role of PTP1B in HER2 Signaling in...AND SUBTITLE 5a. CONTRACT NUMBER Role of PTP1B in HER2 Signaling in Breast Cancer 5b. GRANT NUMBER W81XWH-10-1-1005 5c. PROGRAM ELEMENT NUMBER...2009, Postdoctoral Fellowship Award W81XWH-10-1-1005, “Role of PTP1B in HER2 Signaling in Breast Cancer" INTRODUCTION  The receptor tyrosine

The Transposable Element Mariner Mediates Germline Transformation in Drosophila Melanogaster

PubMed Central

Lidholm, D. A.; Lohe, A. R.; Hartl, D. L.

1993-01-01

A vector for germline transformation in Drosophila melanogaster was constructed using the transposable element mariner. The vector, denoted pMlwB, contains a mariner element disrupted by an insertion containing the wild-type white gene from D. melanogaster, the β-galactosidase gene from Escherichia coli and sequences that enable plasmid replication and selection in E. coli. The white gene is controlled by the promoter of the D. melanogaster gene for heat-shock protein 70, and the β-galactosidase gene is flanked upstream by the promoter of the transposable element P as well as that of mariner. The MlwB element was introduced into the germline of D. melanogaster by co-injection into embryos with an active mariner element, Mos1, which codes for a functional transposase and serves as a helper. Two independent germline insertions were isolated and characterized. The results show that the MlwB element inserted into the genome in a mariner-dependent manner with the termini of the inverted repeats inserted at a TA dinucleotide. Both insertions exhibit an unexpected degree of germline and somatic stability, even in the presence of an active mariner element in the genetic background. These results demonstrate that the mariner transposable element, which is small (1286 bp) and relatively homogeneous in size among different copies, is nevertheless capable of promoting the insertion of the large (13.2 kb) MlwB element. Because of the widespread phylogenetic distribution of mariner among insects, these results suggest that mariner might provide a wide hostrange transformation vector for insects. PMID:8394264

Dietary intake of trace elements, minerals, and vitamins of patients on chronic hemodialysis.

PubMed

Bossola, Maurizio; Di Stasio, Enrico; Viola, Antonella; Leo, Alessandra; Carlomagno, Giusy; Monteburini, Tania; Cenerelli, Stefano; Santarelli, Stefano; Boggi, Rolando; Miggiano, Giacinto; Vulpio, Carlo; Mele, Cristina; Tazza, Luigi

2014-04-01

We aimed to estimate dietary intakes of trace elements, minerals, and vitamins in hemodialysis patients (HDP) of three centers in one metropolitan and two urban areas of Italy. Daily dietary intake was assessed using a 3-day diet diary in 128 HDP. Mean daily intakes of trace elements were as follows: zinc, 7.6 ± 5.4 mg; copper, 14.3 ± 11.8 mg; selenium, 28.3 ± 18.1 μg; and iron, 7.2 ± 4.1 mg (7.8 ± 2.6 mg in women, 6.9 ± 2.4 mg in men). The distribution of patients by daily intakes of trace elements showed most were under the recommended values, with the exception of copper intake, which was much higher. Mean daily intakes of minerals were as follows: magnesium, 174.4 ± 94.3 mg; phosphorus, 842.6 ± 576.8 mg; calcium, 371.8 ± 363.7 mg; potassium, 1,616.2 ± 897.3 mg; and sodium, 1,350 ± 1,281 mg. Mean daily intakes of vitamins were as follows: vitamin A, 486.1 ± 544.6 μg; vitamin B1, 0.86 ± 0.7 mg; vitamin B2, 1.1 ± 0.7 mg; vitamin B3, 13.3 ± 8.1 mg; vitamin C, 47.8 ± 50.3 mg; and vitamin E, 9.5 ± 3.6 mg. The distribution of patients by daily intakes of vitamins showed most were under the recommended values. Daily intakes of trace elements and vitamins were similar among the three centers and did not differ between dialysis and non-dialysis days. Many HDP have daily dietary intakes of trace elements and vitamins below the recommended values, whereas the intake of copper is much higher.

A Singular Differential Equation Stemming from an Optimal Control Problem in Financial Economics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brunovsky, Pavol, E-mail: brunovsky@fmph.uniba.sk; Cerny, Ales, E-mail: ales.cerny.1@city.ac.uk; Winkler, Michael, E-mail: michael.winkler@uni-due.de

2013-10-15

We consider the ordinary differential equation x{sup 2} u'' = axu'+bu-c(u'-1){sup 2}, x Element-Of (0,x{sub 0}), with a Element-Of R, b Element-Of R , c>0 and the singular initial condition u(0)=0, which in financial economics describes optimal disposal of an asset in a market with liquidity effects. It is shown in the paper that if a+b<0 then no continuous solutions exist, whereas if a+b>0 then there are infinitely many continuous solutions with indistinguishable asymptotics near 0. Moreover, it is proved that in the latter case there is precisely one solution u corresponding to the choice x{sub 0}={infinity} which is suchmore » that 0{<=}u(x){<=}x for all x>0, and that this solution is strictly increasing and concave.« less

Semiconductor radiation detector

DOEpatents

Bell, Zane W.; Burger, Arnold

2010-03-30

A semiconductor detector for ionizing electromagnetic radiation, neutrons, and energetic charged particles. The detecting element is comprised of a compound having the composition I-III-VI.sub.2 or II-IV-V.sub.2 where the "I" component is from column 1A or 1B of the periodic table, the "II" component is from column 2B, the "III" component is from column 3A, the "IV" component is from column 4A, the "V" component is from column 5A, and the "VI" component is from column 6A. The detecting element detects ionizing radiation by generating a signal proportional to the energy deposited in the element, and detects neutrons by virtue of the ionizing radiation emitted by one or more of the constituent materials subsequent to capture. The detector may contain more than one neutron-sensitive component.

Effect of alloying elements and heat treatment on the fracture toughness of Ti-Al-Nb alloys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kamat, S.V.; Gogia, A.K.; Banerjee, D.

The fracture toughness and toughening mechanisms of Ti{sub 3}Al based alloy compositions covering a large range of Nb, small variations in Al and quaternary substitutions of Nb have been studied in a variety of heat treated conditions designed to vary the volume fractions of the constituents phases. It was found that the B2 phase of these alloys failed by cleavage in a coarse grained condition but in a ductile manner when fine grained. A higher Nb and a lower Al content improved the cleavage fracture stress of the B2 phase while replacement of a part of Nb and a lowermore » Al content improved the cleavage fracture stress of the B2 phase while replacement of a part of Nb with Mo or Ta had no significant effect. Heat treatments which result in a two phase microstructure ({alpha}{sub 2} + {beta}/B2) exhibited a trend of increasing fracture toughness with increasing volume fraction of {beta}/B2 up to about 60--80 volume fraction of {beta}/B2. This behavior was largely explained by quantifying the role of crack tip blunting. The effect of alloying elements on fracture toughness in two phase microstructures was similar to that observed in the coarse grained B2 condition.« less

34 CFR Appendix B to Part 300 - Proportionate Share Calculation

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 2 2014-07-01 2013-07-01 true Proportionate Share Calculation B Appendix B to Part 300... CHILDREN WITH DISABILITIES Pt. 300, App. B Appendix B to Part 300—Proportionate Share Calculation Each LEA... special education and related services under Part B, as compared with the total number of eligible...

Phase identification in boron-containing powder metallurgy steel using EBSD in combination with EPMA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wu, Ming-Wei, E-mail: mwwu@ntut.edu.tw; Cai, Wen-Zhang

2016-03-15

Boron (B) is extensively used to induce liquid phase sintering (LPS) in powder metallurgy (PM) steels and thereby increase the densification. The alloying elements in B-containing PM steels affect the boride phase, stability of the boride, the temperature of liquid formation, and the progress of LPS. However, the boride phase has not been systematically identified yet. The main objective of this study was to clarify the influences of alloying elements, including C, Cr, and Ni, on the boride phases using electron backscatter diffraction (EBSD) in combination with electron probe microanalysis (EPMA). Network structures consisting of ferrite, Fe{sub 2}B boride, andmore » Fe{sub 3}C carbide were extensively observed in the Fe–0.4B–0.5C steel. The portions of Fe{sub 2}B were sufficiently larger than those of Fe{sub 3}C, and Fe{sub 3}C was mostly distributed at the interfaces between ferrite and Fe{sub 2}B. Adding 1.5 wt.% Cr or 1.8 wt.% Ni to Fe–0.4B–0.5C steel completely changes the Fe{sub 2}B and Fe{sub 3}C phases to a M{sub 3}(B,C) phase, where M represents the metallic elements, including Fe, Cr, Mo, and Ni. Furthermore, Cr, Mo, B, and C atoms tend to concentrate on the M{sub 3}(B,C) phase, but Ni atoms do not. - Highlights: • Network structures consisting of ferrite, Fe{sub 2}B boride, and Fe{sub 3}C carbide were extensively observed in the Fe–0.4B–0.5C steel. • Adding 1.5 wt.% Cr or 1.8 wt.% Ni to Fe–0.4B–0.5C steel completely transforms the Fe{sub 2}B and Fe{sub 3}C phases to a M{sub 3}(B,C) phase. • Cr, Mo, B, and C atoms tend to concentrate on the M{sub 3}(B,C) phase, but Ni atoms do not.« less

45 CFR 2519.120 - What is the Federal Work-Study requirement?

Code of Federal Regulations, 2010 CFR

2010-10-01

... NATIONAL AND COMMUNITY SERVICE HIGHER EDUCATION INNOVATIVE PROGRAMS FOR COMMUNITY SERVICE Purpose and... under this part, an institution of higher education must demonstrate that it meets the minimum requirements under section 443(b)(2)(A) of the Higher Education Act of 1965 (42 U.S.C. 2753(b)(2)(A)) relating...

First Staphylococcal Cassette Chromosome mec Containing a mecB-Carrying Gene Complex Independent of Transposon Tn6045 in a Macrococcus caseolyticus Isolate from a Canine Infection

PubMed Central

Gómez-Sanz, Elena; Schwendener, Sybille; Thomann, Andreas; Gobeli Brawand, Stefanie

2015-01-01

A methicillin-resistant mecB-positive Macrococcus caseolyticus (strain KM45013) was isolated from the nares of a dog with rhinitis. It contained a novel 39-kb transposon-defective complete mecB-carrying staphylococcal cassette chromosome mec element (SCCmecKM45013). SCCmecKM45013 contained 49 coding sequences (CDSs), was integrated at the 3′ end of the chromosomal orfX gene, and was delimited at both ends by imperfect direct repeats functioning as integration site sequences (ISSs). SCCmecKM45013 presented two discontinuous regions of homology (SCCmec coverage of 35%) to the chromosomal and transposon Tn6045-associated SCCmec-like element of M. caseolyticus JCSC7096: (i) the mec gene complex (98.8% identity) and (ii) the ccr-carrying segment (91.8% identity). The mec gene complex, located at the right junction of the cassette, also carried the β-lactamase gene blaZm (mecRm-mecIm-mecB-blaZm). SCCmecKM45013 contained two cassette chromosome recombinase genes, ccrAm2 and ccrBm2, which shared 94.3% and 96.6% DNA identity with those of the SCCmec-like element of JCSC7096 but shared less than 52% DNA identity with the staphylococcal ccrAB and ccrC genes. Three distinct extrachromosomal circularized elements (the entire SCCmecKM45013, ΨSCCmecKM45013 lacking the ccr genes, and SCCKM45013 lacking mecB) flanked by one ISS copy, as well as the chromosomal regions remaining after excision, were detected. An unconventional circularized structure carrying the mecB gene complex was associated with two extensive direct repeat regions, which enclosed two open reading frames (ORFs) (ORF46 and ORF51) flanking the chromosomal mecB-carrying gene complex. This study revealed M. caseolyticus as a potential disease-associated bacterium in dogs and also unveiled an SCCmec element carrying mecB not associated with Tn6045 in the genus Macrococcus. PMID:25987634

Lumped element kinetic inductance detectors based on two-gap MgB2 thin films

NASA Astrophysics Data System (ADS)

Yang, C.; Niu, R. R.; Guo, Z. S.; Cai, X. W.; Chu, H. M.; Yang, K.; Wang, Y.; Feng, Q. R.; Gan, Z. Z.

2018-01-01

Lumped element kinetic inductance detectors (LEKIDs) are made from a single layer superconducting thin film. Because of their low noise and highly multiplexibility, LEKIDs provide a sensitive technology for the detection of millimeter and submillimeter waves. In this work, a 5-pixel 50-nm-thick MgB2 array is made. The microwave properties of the array are measured under dark conditions. We show that the loaded quality factor Q of the resonant circuit is 30 000 at 7.5 K, which is comparable to that of lower-operating-temperature (usually several hundred mK) LEKIDs made from superconductors such as Al and Nb. Moreover, the temperature dependence of resonance frequency gives the two-gap character of MgB2, Δπ (0) = 2.58 meV and Δσ (0) = 8.26 meV. The gap frequency (f = 2Δ/h) indicates that MgB2 LEKIDs have a promising application on terahertz detection.

Secondary structure model of the RNA recognized by the reverse transcriptase from the R2 retrotransposable element.

PubMed Central

Mathews, D H; Banerjee, A R; Luan, D D; Eickbush, T H; Turner, D H

1997-01-01

RNA transcripts corresponding to the 250-nt 3' untranslated region of the R2 non-LTR retrotransposable element are recognized by the R2 reverse transcriptase and are sufficient to serve as templates in the target DNA-primed reverse transcription (TPRT) reaction. The R2 protein encoded by the Bombyx mori R2 can recognize this region from both the B. mori and Drosophila melanogaster R2 elements even though these regions show little nucleotide sequence identity. A model for the RNA secondary structure of the 3' untranslated region of the D. melanogaster R2 retrotransposon was developed by sequence comparison of 10 species aided by free energy minimization. Chemical modification experiments are consistent with this prediction. A secondary structure model for the 3' untranslated region of R2 RNA from the R2 element from B. mori was obtained by a combination of chemical modification data and free energy minimization. These two secondary structure models, found independently, share several common sites. This study shows the utility of combining free energy minimization, sequence comparison, and chemical modification to model an RNA secondary structure. PMID:8990394

Trace element concentrations in needles and bark of Larix Sibirica within the Mo-W ore field (Buryat Republic, Russia)

NASA Astrophysics Data System (ADS)

Timofeev, Ivan; Kosheleva, Natalia

2016-04-01

The present study aims to assess the changes in the trace element (TE) composition of Larix Sibirica species growing in the impact area of Dzhida Mo-W plant in the Zakamensk city. The objectives of the study were: (1) to reveal the biogeochemical background features and changes in the TE composition of larch needles and bark in the mining region; (2) to determine patterns of spatial distribution of TE content in larch organs; (3) to assess the ecological state of larch plantation in different land-use zones of the city. A landscape-geochemical survey of the territory was carried out in summer of 2013. Total of 21 mixed (taken from 3-5 trees) samples of needles and bark were collected in undisturbed and different land-use areas. The bulk contents of TEs in dry plant samples were analyzed by mass spectrometry with induced coupled plasma. Sixteen priority pollutants were selected for thorough analysis, including elements of hazard classes I (Zn, As, Pb, Cd), II (Cr, Co, Ni, Cu, Mo, Sb), III (V, Sr, Ba, W), and some others (Sn, Bi). Concentrations of TEs (C_b) in background trees were compared with the global clarks (C_g) for annual increment of terrestrial vegetation (Dobrovol'skii 2003) via calculating the global enrichment EF_g=C_b/Cg and dispersion factors DF_g=C_g/C_b}. The concentrations of the elements in the urban samples Ci were grouped depending on the type of land use and compared with the background (C_b) via calculating the local enrichment EF_l=C_i/Cb and dispersion factors DF_l=C_b/C_i. The ecological state of the urban plants was diagnosed using three TE ratios. The Fe/Mn ratio represents photosynthetic activity with optimum value 1.5-2.5. The Pb/Mn ratio characterizes balance between technogenic and biophilic elements, its value for unpolluted terrestrial plants is 0.006. The Cu/Zn ratio determines the proportionality in the provision of enzyme synthesis with these metals, its optimum value is 0.27. TE composition of needles of background larch is characterized by increased concentrations of ?? ? Mn (EF_g=2.9) ? Sr (1.5), and reduced ones for Ni, Co, Pb, Mo, Sn, V (DF_l=5.1-22.1), that of Cd, Cu, Zn are close to global clarks. Ba, Pb, Cd (EF_g=3.5-2.3) are accumulated in the bark, Cu, Zn, Co, Cr, Ni, Sn dissipate (DF_g=2.1-3.7), and the content of Mn, Sr, Mo, V, As is close to Cg. In the city larch needles accumulate Cr (EF_l=37.8), W (18.9), V, Pb, Bi (8.6-11.4), Sb, Ni, Cd, Sn (6.6-2.5); Mn (DF_l=3.1) is among scattered. Changes in the TE composition of larch bark is most clearly evident in the industrial area, where high concentrations of W, Sn (EF_l=5.4-6.6), Sb, Pb, As (2.8-3.4), Mo, Cd, V, Bi, Zn (1.5-2.0) and low ones -- of Cr, Ni, Co, Ba (DF_l=4.6-2.1) are observed. As an indicator of long-term pollution, bark displays that vegetation of industrial zone has been subject previously to most intense anthropogenic impact, so, Pb/Mn=0.06 was there the highest. After plant closing residential area experiences the greatest impact according to Fe/Mn=4.7; Pb/Mn=0.04 values in the needles. This is caused by the active transport of aeolian dry material of tailings. 1. Dobrovol'skii VV (2003) Basics of biogeochemistry: the textbook for students of higher educational institutions. Moscow, "Academia" Publ., 400 p.

Complexes of a dianionic bis(diphosphinomethanide) with lithium, sodium, potassium and zirconium. Effect of substitution on the Schlenk dimerisation of vinylidene phosphines.

PubMed

Izod, Keith; McFarlane, William; Tyson, Brent V; Clegg, William; Harrington, Ross W

2004-12-07

The vinylidene phosphine (Pr(n)(2)P)(2)C=CH(2) (1) undergoes Schlenk dimerisation on treatment with an excess of any of the alkali metals Li, Na or K to give the butane-1,4-diide complexes [(L)M{(Pr(n)(2)P)(2)CCH(2)}](2)[(L)M =(THF)(2)Li (6), (THF)(3)Na (7b), (DME)(2)K (8b)], after recrystallisation. Whereas the reaction between the analogous phenyl derivative (Ph(2)P)(2)C=CH(2) and K results in cleavage of a P-C bond, 1 reacts smoothly with K to give 8, with no evidence for P-C cleavage. Compound 6 is an excellent ligand transfer reagent: metathesis reactions between either 6 or its phenyl analogue [(THF)(2)Li{(Ph(2)P)(2)CCH(2)}](2) (2) and two equivalents of Cp(2)ZrCl(2) in THF give the corresponding dinuclear zirconocene derivatives [Cp(2)Zr(Cl){(R(2)P)(2)CCH(2)}](2) in good yields [R = Ph (11), Pr(n)(12)]. Compounds 6, 7b, 8b, 11 and 12 have been characterised by multi-element NMR spectroscopy and, where possible, by elemental analysis; compounds 6, 7b, 11 and 12 have additionally been characterised by X-ray crystallography.

28 CFR Appendix B to Part 61 - Drug Enforcement Administration Procedures Relating to the Implementation of the National...

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Drug Enforcement Administration... ENVIRONMENTAL POLICY ACT Pt. 61, App. B Appendix B to Part 61—Drug Enforcement Administration Procedures.... This part applies to all organizational elements of the Drug Enforcement Administration [DEA]. 2...

Micromachined High Frequency PMN-PT/Epoxy 1-3 Composite Ultrasonic Annular Array

PubMed Central

Liu, Changgeng; Djuth, Frank; Li, Xiang; Chen, Ruimin; Zhou, Qifa; Shung, K. Kirk

2013-01-01

This paper reports the design, fabrication, and performance of miniature micromachined high frequency PMN-PT/epoxy 1-3 composite ultrasonic annular arrays. The PMN-PT single crystal 1-3 composites were made with micromachining techniques. The area of a single crystal pillar was 9 μm × 9 μm. The width of the kerf among pillars was ~ 5 μm and the kerfs were filled with a polymer. The composite thickness was 25 μm. A six-element annular transducer of equal element area of 0.2 mm2 with 16 μm kerf widths between annuli was produced. The aperture size the array transducer is about 1.5 mm in diameter. A novel electrical interconnection strategy for high density array elements was implemented. After the transducer was attached to the electric connection board and packaged, the array transducer was tested in a pulse/echo arrangement, whereby the center frequency, bandwidth, two-way insertion loss (IL), and cross talk between adjacent elements were measured for each annulus. The center frequency was 50 MHz and -6 dB bandwidth was 90%. The average insertion loss was 19.5 dB at 50 MHz and the crosstalk between adjacent elements was about -35 dB. The micromachining techniques described in this paper are promising for the fabrication of other types of high frequency transducers e.g. 1D and 2D arrays. PMID:22119324

The fission yeast CENP-B protein Abp1 prevents pervasive transcription of repetitive DNA elements.

PubMed

Daulny, Anne; Mejía-Ramírez, Eva; Reina, Oscar; Rosado-Lugo, Jesus; Aguilar-Arnal, Lorena; Auer, Herbert; Zaratiegui, Mikel; Azorin, Fernando

2016-10-01

It is well established that eukaryotic genomes are pervasively transcribed producing cryptic unstable transcripts (CUTs). However, the mechanisms regulating pervasive transcription are not well understood. Here, we report that the fission yeast CENP-B homolog Abp1 plays an important role in preventing pervasive transcription. We show that loss of abp1 results in the accumulation of CUTs, which are targeted for degradation by the exosome pathway. These CUTs originate from different types of genomic features, but the highest increase corresponds to Tf2 retrotransposons and rDNA repeats, where they map along the entire elements. In the absence of abp1, increased RNAPII-Ser5P occupancy is observed throughout the Tf2 coding region and, unexpectedly, RNAPII-Ser5P is enriched at rDNA repeats. Loss of abp1 also results in Tf2 derepression and increased nucleolus size. Altogether these results suggest that Abp1 prevents pervasive RNAPII transcription of repetitive DNA elements (i.e., Tf2 and rDNA repeats) from internal cryptic sites. Copyright © 2016 Elsevier B.V. All rights reserved.

New Perspectives on School Improvement: A Summary of Research Findings on Approaches to Educational Reform and the Management of School Systems.

ERIC Educational Resources Information Center

Organizational Analysis and Practice, Inc., Ithaca, NY. Educational Systems Div.

Although educational reform approaches have varied from state to state, most efforts have shared some common elements: (1) concentration of educational policymaking in state capitols by state-level officials; (2) a widespread conviction that schools of education, local school officials, and teachers are unwilling or unable to "reform"…

34 CFR 200.26 - Core elements of a schoolwide program.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Core elements of a schoolwide program. 200.26 Section 200.26 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND... Improving Basic Programs Operated by Local Educational Agencies Schoolwide Programs § 200.26 Core elements...

Regulation of P-element transposase activity in Drosophila melanogaster by hobo transgenes that contain KP elements.

PubMed Central

Simmons, Michael J; Haley, Kevin J; Grimes, Craig D; Raymond, John D; Fong, Joseph C L

2002-01-01

Fusions between the Drosophila hsp70 promoter and three different incomplete P elements, KP, SP, and BP1, were inserted into the Drosophila genome by means of hobo transformation vectors and the resulting transgenic stocks were tested for repression of P-element transposase activity. Only the H(hsp/KP) transgenes repressed transposase activity, and the degree of repression was comparable to that of a naturally occurring KP element. The KP transgenes repressed transposase activity both with and without heat-shock treatments. Both the KP element and H(hsp/KP) transgenes repressed the transposase activity encoded by the modified P element in the P(ry(+), Delta2-3)99B transgene more effectively than that encoded by the complete P element in the H(hsp/CP)2 transgene even though the P(ry(+), Delta2-3)99B transgene was the stronger transposase source. Repression of both transposase sources appeared to be due to a zygotic effect of the KP element or transgene. There was no evidence for repression by a strictly maternal effect; nor was there any evidence for enhancement of KP repression by the joint maternal transmission of H(hsp/KP) and H(hsp/CP) transgenes. These results are consistent with the idea that KP-mediated repression of P-element activity involves a KP-repressor polypeptide that is not maternally transmitted and that KP-mediated repression is not strengthened by the 66-kD repressor produced by complete P elements through alternate splicing of their RNA. PMID:12019235

New concepts of science and medicine in science and technology studies and their relevance to science education.

PubMed

Wang, Hsiu-Yun; Stocker, Joel F; Fu, Daiwie

2012-02-01

Science education often adopts a narrow view of science that assumes the lay public is ignorant, which seemingly justifies a science education limited to a promotional narrative of progress in the form of scientific knowledge void of meaningful social context. We propose that to prepare students as future concerned citizens of a technoscientific society, science education should be informed by science, technology, and society (STS) perspectives. An STS-informed science education, in our view, will include the following curricular elements: science controversy education, gender issues, historical perspective, and a move away from a Eurocentric view by looking into the distinctive patterns of other regional (in this case of Taiwan, East Asian) approaches to science, technology, and medicine. This article outlines the significance of some major STS studies as a means of illustrating the ways in which STS perspectives can, if incorporated into science education, enhance our understanding of science and technology and their relationships with society. Copyright © 2011. Published by Elsevier B.V.

Education in Japan: What Does It Mean to the U.S.?

ERIC Educational Resources Information Center

Nommay, Louanne

This study surveys recent literature on education in Japan to determine what elements of the Japanese educational system could be incorporated into America's pedagogical system. There are four sections with the following titles: (1) What comparisons are being made between Japanese and American students in achievement and IQ tests scores? (2) How…

Architecture and Children: Learning Environments and Design Education.

ERIC Educational Resources Information Center

Taylor, Anne, Ed.; Muhlberger, Joe, Ed.

1998-01-01

This issue addresses (1) growing international interest in learning environments and their effects on behavior, and (2) design education, an integrated model for visual-spatial lifelong learning. It focuses on this new and emerging integrated field which integrates elements in education, new learning environment design, and the use of more two-…

A Cross-Case Analysis of Three Social Justice-Oriented Education Programs

ERIC Educational Resources Information Center

Rodriguez, Mariela A.; Chambers, Terah Venzant; Gonzalez, Maria Luisa; Scheurich, James Joseph

2010-01-01

This cross-case analysis was based on three main questions that addressed three social justice-oriented education programs. The three questions were: 1) What critical elements underlie programs that prepare professionals for social justice? 2) What can we learn from these programs in support of educational-leadership programs whose aim is to…

A STUDY OF THE CRITICAL REQUIREMENTS FOR DIRECTORS IN EDUCATIONAL TELEVISION STATIONS.

ERIC Educational Resources Information Center

ADKINS, GALE R.

THIS RESEARCH STUDY WAS DESIGNED TO ANSWER 3 QUESTIONS CONCERNING THE DIRECTION AND DIRECTORS OF EDUCATIONAL TELEVISION STATIONS--(1) WHAT ELEMENTS OF DIRECTOR BEHAVIOR APPEAR MOST OFTEN IN JUDGMENTS OF DIRECTOR EFFECTIVENESS MADE BY TV STATION MANAGEMENT PERSONNEL, (2) WHAT ARE THE NON-BEHAVIORAL CHARACTERISTICS (I.E., AGE, EDUCATION, WORK…

Geochemistry of trace elements in coals from the Zhuji Mine, Huainan Coalfield, Anhui, China

USGS Publications Warehouse

Sun, R.; Liu, Gaisheng; Zheng, Lingyun; Chou, C.-L.

2010-01-01

The abundances of nine major elements and thirty-eight trace elements in 520 samples of low sulfur coals from the Zhuji Mine, Huainan Coalfield, Anhui, China, were determined. Samples were mainly collected from 10 minable coal seams of 29 boreholes during exploration. The B content in coals shows that the influence of brackish water decreased toward the top of coal seams; marine transgression and regression occurred frequently in the Lower Shihezi Formation. A wide range of elemental abundances is found. Weighted means of Na, K, Fe, P, Be, B, Co, Ni, Cr, Se, Sb, Ba, and Bi abundances in Zhuji coals are higher, and the remainder elements are either lower or equal to the average values of elements in coals of northern China. Compared to the Chinese coals, the Zhuji coals are higher in Na, K, Be, B, Cr, Co, Se, Sn, Sb, and Bi, but lower in Ti, P, Li, V and Zn. The Zhuji coals are lower only in S, P, V and Zn than average U.S. and world coals. Potassium, Mg, Ca, Mn, Sr, As, Se, Sb and light rare earth elements (LREE) had a tendency to be enriched in thicker coal seams, whereas Fe, Ti, P, V, Co, Ni, Y, Mo, Pb and heavy rare earth elements (HREE) were inclined to concentrate in thinner coal seams. The enrichment of some elements in the Shanxi or Upper Shihezi Formations is related to their depositional environments. The elements are classified into three groups based on their stratigraphic distributions from coal seams 3 to 11-2, and the characteristics of each group are discussed. Lateral distributions of selected elements are also investigated. The correlation coefficients of elemental abundances with ash content show that the elements may be classified into four groups related to modes of occurrence of these elements. ?? 2009 Elsevier B.V. All rights reserved.

Geochemical study of stream waters affected by mining activities in the SE Spain

NASA Astrophysics Data System (ADS)

Garcia-Lorenzo, Maria Luz; Perez-Sirvent, Carmen; Martinez-Sanchez, Maria Jose; Bech, Jaime

2015-04-01

Water pollution by dissolved metals in mining areas has mainly been associated with the oxidation of sulphide-bearing minerals exposed to weathering conditions, resulting in low quality effluents of acidic pH and containing a high level of dissolved metals. According to transport process, three types of pollution could be established: a) Primary contamination, formed by residues placed close to the contamination sources; b) Secondary contamination, produced as a result of transport out of its production areas; c) Tertiary contamination. The aim of this work was to study trace element in water samples affected by mining activities and to apply the MINTEQ model for calculating aqueous geochemical equilibria. The studied area constituted an important mining centre for more than 2500 years, ceasing activity in 1991. The ore deposits of this zone have iron, lead and zinc as the main metal components. As a result, a lot of contaminations sources, formed by mining steriles, waste piles and foundry residues are present. For this study, 36 surficial water samples were collected after a rain episode in 4 different areas. In these samples, the trace element content was determined by by flame atomic absorption spectrometry (Fe and Zn), electrothermal atomization atomic absorption spectrometry (Pb and Cd), atomic fluorescence spectrometry (As) and ICP-MS for Al. MINTEQA2 is a geochemical equilibrium speciation model capable of computing equilibria among the dissolved, adsorbed, solid, and gas phases in an environmental setting and was applied to collected waters. Zone A: A5 is strongly influenced by tailing dumps and showed high trace element content. In addition, is influenced by the sea water and then showed high bromide, chloride, sodium and magnesium content, together with a basic pH. The MINTEQ model application suggested that Zn and Cd could precipitate as carbonate (hidrocincite, smithsonite and otavite). A9 also showed acid pH and high trace element content; is influenced by tailing dumps and also by waters from gully watercourses, transporting materials from Sierra Minera. The MINTEQ simulation showed that Pb and Ca could precipitate as sulphates (anglesite and gypsum). Waters affected by secondary contamination have been mixed with carbonate materials, present in the zone increasing the pH. Some elements have precipitated, such as Cu and Pb, while Cd, Zn and As are soluble. The MINTEQ model results showed that in A10 and A14, Al could precipitate as diaspore but also carbonates could be formed, particularly dolomite. These model in A12 sample showed that soluble Zn could precipitate as carbonate and Al as oxyhydroxide, similarly than in A13. A2 and A6 waters are affected by tertiary contamination and showed basic pH, soluble carbonates and lower trace element content. Only Zn, Cd and Al are present. The speciation model showed that in A2, Cd and Zn could precipitate as carbonates while Al as oxihydroxide. In A6, the model suggested that soluble Pb could precipitate as carbonate (hidrocerusite and cerusite) or as hydroxide; Al as diaspore, Ca as calcite and Fe as hematite. Zone B: All waters are strongly affected by mining activities and showed acid pH, high trace element content and high content of soluble sulphates. The MINTEQ results showed that in B8, Fe could precipitate as hydroxychloride and in B12 could form alunite. In B9, B10, B13 y B14, the model estimates the precipitation of anglesite, gypsum and Fe hydroxichloride (B9 and B10), diaspore in B13 and B14, and gypsum and Fe hydroxychloride in B13. All the sampling points collected in Zone C are affected by primary contamination, because there are a lot of tailing dumps. C1 showed high trace element content because is a reception point of a lot of tailing dumps. Water samples from C3 to C8 also had acid pH and high trace element content, particularly As, Zn and Cd. In addition, they showed high soluble sulphates. C2 water showed neutral pH, soluble carbonate and low trace element content because is influenced by a stabilised tailing dump. In all samples, except C2, the MINTEQ model showed that a lot of efflorescences could be formed, mainly sulphates. Zone D: All waters collected in this zone showed acid pH and high trace element content, mainly Zn, Cd and As. MINTEQ model results showed that elements could precipitate as jarosite but also anglesite in D8 and gypsum in D9, D11 and D12. D1 is affected by secondary contamination, which showed higher pH (still acid) and lower content in soluble salts and trace elements. The MINTEQ model suggested that Al could precipitate as diaspore, gibbsite and alunite. The applied model is an appropriate tool for the analysis of waters affected by mining activities. The obtained simulations confirm natural attenuation processes.

Computational Overlap Coupling Between Micropolar Linear Elastic Continuum Finite Elements and Nonlinear Elastic Spherical Discrete Elements in One Dimension

DTIC Science & Technology

2013-01-01

Cracking in asphalt pavement . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Figure 2. 2D...metallic binder, figure 1(b)), particulate energetic materials (explosive crystalline grains with polymeric binder, figure 1(c)), asphalt pavement (stone...explosive HMX grains and at grain-matrix interfaces (2). (d) Cracking in asphalt pavement . 2 (i) it is limited by current computing power (even

Micromachining Techniques in Developing High-Frequency Piezoelectric Composite Ultrasonic Array Transducers

PubMed Central

Liu, Changgeng; Djuth, Frank T.; Zhou, Qifa; Shung, K. Kirk

2014-01-01

Several micromachining techniques for the fabrication of high-frequency piezoelectric composite ultrasonic array transducers are described in this paper. A variety of different techniques are used in patterning the active piezoelectric material, attaching backing material to the transducer, and assembling an electronic interconnection board for transmission and reception from the array. To establish the feasibility of the process flow, a hybrid test ultrasound array transducer consisting of a 2-D array having an 8 × 8 element pattern and a 5-element annular array was designed, fabricated, and assessed. The arrays are designed for a center frequency of ~60 MHz. The 2-D array elements are 105 × 105 μm in size with 5-μm kerfs between elements. The annular array surrounds the square 2-D array and provides the option of transmitting from the annular array and receiving with the 2-D array. Each annular array element has an area of 0.71 mm2 with a 16-μm kerf between elements. The active piezoelectric material is (1 − x) Pb(Mg1/3Nb2/3)O3−xPbTiO3 (PMN-PT)/epoxy 1–3 composite with a PMN-PT pillar lateral dimension of 8 μm and an average gap width of ~4 μm, which was produced by deep reactive ion etching (DRIE) dry etching techniques. A novel electric interconnection strategy for high-density, small-size array elements was proposed. After assembly, the array transducer was tested and characterized. The capacitance, pulse–echo responses, and crosstalk were measured for each array element. The desired center frequency of ~60 MHz was achieved and the −6-dB bandwidth of the received signal was ~50%. At the center frequency, the crosstalk between adjacent 2-D array elements was about −33 dB. The techniques described herein can be used to build larger arrays containing smaller elements. PMID:24297027

High-Level Heat Resistance of Spores of Bacillus amyloliquefaciens and Bacillus licheniformis Results from the Presence of a spoVA Operon in a Tn1546 Transposon

PubMed Central

Berendsen, Erwin M.; Koning, Rosella A.; Boekhorst, Jos; de Jong, Anne; Kuipers, Oscar P.; Wells-Bennik, Marjon H. J.

2016-01-01

Bacterial endospore formers can produce spores that are resistant to many food processing conditions, including heat. Some spores may survive heating processes aimed at production of commercially sterile foods. Recently, it was shown that a spoVA operon, designated spoVA2mob, present on a Tn1546 transposon in Bacillus subtilis, leads to profoundly increased wet heat resistance of B. subtilis spores. Such Tn1546 transposon elements including the spoVA2mob operon were also found in several strains of Bacillus amyloliquefaciens and Bacillus licheniformis, and these strains were shown to produce spores with significantly higher resistances to wet heat than their counterparts lacking this transposon. In this study, the locations and compositions of Tn1546 transposons encompassing the spoVA2mob operons in B. amyloliquefaciens and B. licheniformis were analyzed. Introduction of these spoVA2mob operons into B. subtilis 168 (producing spores that are not highly heat resistant) rendered mutant 168 strains that produced high-level heat resistant spores, demonstrating that these elements in B. amyloliquefaciens and B. licheniformis are responsible for high level heat resistance of spores. Assessment of growth of the nine strains of each species between 5.2°C and 57.7°C showed some differences between strains, especially at lower temperatures, but all strains were able to grow at 57.7°C. Strains of B. amyloliquefaciens and B. licheniformis that contain the Tn1546 elements (and produce high-level heat resistant spores) grew at temperatures similar to those of their Tn1546-negative counterparts that produce low-level heat resistant spores. The findings presented in this study allow for detection of B. amyloliquefaciens and B. licheniformis strains that produce highly heat resistant spores in the food chain. PMID:27994575

Development of a 35-MHz piezo-composite ultrasound array for medical imaging.

PubMed

Cannata, Jonathan M; Williams, Jay A; Zhou, Qifa; Ritter, Timothy A; Shung, K Kirk

2006-01-01

This paper discusses the development of a 64-element 35-MHz composite ultrasonic array. This array was designed primarily for ocular imaging applications, and features 2-2 composite elements mechanically diced out of a fine-grain high-density Navy Type VI ceramic. Array elements were spaced at a 50-micron pitch, interconnected via a custom flexible circuit and matched to the 50-ohm system electronics via a 75-ohm transmission line coaxial cable. Elevation focusing was achieved using a cylindrically shaped epoxy lens. One functional 64-element array was fabricated and tested. Bandwidths averaging 55%, 23-dB insertion loss, and crosstalk less than -24 dB were measured. An image of a tungsten wire target phantom was acquired using a synthetic aperture reconstruction algorithm. The results from this imaging test demonstrate resolution exceeding 50 microm axially and 100 microm laterally.

Main Battle Tank Flexible Gun Tube Disturbance Model: Three-Segment Model

DTIC Science & Technology

2002-10-01

Laplace transform of equation (1) yields Ix,(s) F. (s)l [a] o2(s)[ = 2 , (s) (2) Theelmets f a]and[ 0{2(S) jjSO,(S)13o( s )) oP (S)J The elements of [a...contain the actuator force, F,, and the actuator displacement, x,, in addition to disturbances (s2y,(s), sOp( s ), Op (s)) and the responses 01(s), 02(s), •3...function. The portion of the response due to the disturbance is X, (s) B2 B13 B14 1fs2y(s) 2°s(s) B4 s OP (s) J (7) 02(S) B2 B33 B34 op (S)J 103S) -B2

One base pair change abolishes the T cell-restricted activity of a kB-like proto-enhancer element from the interleukin 2 promoter.

PubMed Central

Briegel, K; Hentsch, B; Pfeuffer, I; Serfling, E

1991-01-01

The inducible, T cell-specific enhancers of murine and human Interleukin 2 (Il-2) genes contain the kB-like sequence GGGATTTCACC as an essential cis-acting enhancer motif. When cloned in multiple copies this so-called TCEd (distal T cell element) acts as an inducible proto-enhancer element in E14 T lymphoma cells, but not in HeLa cells. In extracts of induced, Il-2 secreting El4 cells three individual protein factors bind to TCEd DNA. The binding of the most prominent factor, named TCF-1 (T cell factor 1), is correlated with the proto-enhancer activity of TCEd. TCF-1 consists of two polypeptides of about 50 kD and 105 kD; the former seems to be related to the 50 kD polypeptide of NF-kB. Purified NF-kB is also able to bind to the TCEd, but TCF-1 binds stronger than NF-kB to TCEd DNA. The conversion of the TCEd to a 'perfect' NF-kB binding site leads to a tighter binding of NF-kB to TCEd DNA and, as a functional consequence, to the activity of the 'converted' TCEd motifs in HeLa cells. Thus, the substitution of the underlined A residue to a C within the GGGATTTCACC motif abolishes its T cell-restricted activity and leads to its functioning in both El4 cells and HeLa cells. These results indicate that lymphocyte-specific factors binding to the TCEd are involved in the control of T cell specific-transcription of the Il-2 gene. Images PMID:1945879

Certification of the methylmercury content in SRM 2977 mussel tissue (organic contaminants and trace elements) and SRM 1566b oyster tissue.

PubMed

Tutschku, S; Schantz, M M; Horvat, M; Logar, M; Akagi, H; Emons, H; Levenson, M; Wise, S A

2001-02-01

The methylmercury content in two new marine bivalve mollusk tissue Standard Reference Materials (SRMs) has been certified using results of analyses from the National Institute of Standards and Technology (NIST) and two other laboratories. The certified concentrations of methylmercury were established based on the results from four and six different (independent) analytical methods, respectively, for SRM 1566b Oyster Tissue (13.2 +/- 0.7 microg/kg) and SRM 2977 Mussel Tissue (organic contaminants and trace elements) (36.2 +/- 1.7 microg/kg). The certified concentration of methylmercury in SRM 1566b is among the lowest in any certified reference material (CRM).

Metallic elements and metalloids in Boletus luridus, B. magnificus and B. tomentipes mushrooms from polymetallic soils from SW China.

PubMed

Falandysz, Jerzy; Zhang, Ji; Wiejak, Anna; Barałkiewicz, Danuta; Hanć, Anetta

2017-08-01

Yunnan Province in China is known for its high biodiversity of mushrooms and a diverse geochemistry of soil bedrock and polymetallic soils, but our knowledge of mineral compositions of mushrooms from Yunnan is scarce. The metallic trace elements, Ag, Ba, Co, Cd, Cs, Cu, Cr, Hg, Li, Mn, Ni, Pb, Rb, Sr, V, Tl, U and Zn, and the metalloids, As and Sb, have been investigated using validated methods with a dynamic reactive cell by mass spectroscopy - inductive coupled plasma and cold vapour - atomic absorption spectroscopy on three popular species of Boletus mushrooms from Southwestern China. The trace mineral profiles in caps and stipes of B. luridus (24 individuals), B. magnificus (29 individuals) and B. tomentipes (38 individuals) have been evaluated. The interspecific differences in the content of several trace elements could be attributed to known differences in the geochemistry of soils in Yunnan, but for copper a difference was observed within species. The mean values of concentrations in composite samples of caps for B. luridus, B. magnificus and B. tomentipes from three to four locations were at the ranges (mgkg -1 dry biomass): Ag (1.3-3.7), As (0.79-53), Ba (4.0-12), Co (0.68-1.2), Cd (0.79-2.2), Cs (0.67-55), Cu (37-77), Cr (5.0-7.6), Hg (2.1-5.4), Li (0.15-0.61), Mn (13-28), Ni (0.86-4.6), Pb (0.59-1.8), Rb (90-120), Sb (0.014-0.088), Sr (0.63-1.6), V (1.4-2.2), Tl (0.017-0.054), U (0.029-0.065) and Zn (130-180). Caps of Boletus mushrooms were richer in Ag, Cu, Hg and Zn than stipes, while other elements were distributed roughly equally between both morphological parts. B. luridus, B. magnificus and B. tomentipes grew in certain sites in Yunnan contained Ag, As, Ba, Cr, Hg, Ni, Sr or V at elevated concentration. A specific geochemistry of the soils type (latosols, lateritic red earths, and red and yellow earths in the Circum-Pacific Mercuriferous Belt of Southwestern China) can explain occurrence of some minerals at greater or elevated amount in mushrooms in Yunnan, while number of available research and data on mineral composition of mushrooms due to geochemical anomalies of soil parent material is so far little. Copyright © 2017 Elsevier Inc. All rights reserved.

Influence of case-based e-learning on students' performance in point-of-care ultrasound courses: a randomized trial.

PubMed

Hempel, Dorothea; Sinnathurai, Sivajini; Haunhorst, Stephanie; Seibel, Armin; Michels, Guido; Heringer, Frank; Recker, Florian; Breitkreutz, Raoul

2016-08-01

Theoretical knowledge, visual perception, and sensorimotor skills are key elements in ultrasound education. Classroom-based presentations are used routinely to teach theoretical knowledge, whereas visual perception and sensorimotor skills typically require hands-on training (HT). We aimed to compare the effect of classroom-based lectures versus a case-based e-learning (based on clinical cases only) on the hands-on performance of trainees during an emergency ultrasound course. This is a randomized, controlled, parallel-group study. Sixty-two medical students were randomized into two groups [group 1 (G1) and group 2 (G2)]. G1 (n=29) was subjected to a precourse e-learning, based on 14 short screencasts (each 5 min), an on-site discussion (60 min), and a standardized HT session on the day of the course. G2 (n=31) received classroom-based presentations on the day of the course before an identical HT session. Both groups completed a multiple-choice (MC) pretest (test A), a practical postcourse test (objective structured clinical exam), and MC tests directly after the HT (test B) and 1 day after the course (test C). The Mann-Whitney U-test was used for statistical analysis. G1 performed markedly better in test A (median 84.2, 25%; 75% percentile: 68.5; 92.2) compared with G2 (65.8; 53.8; 80.4), who had not participated in case-based e-learning (P=0.0009). No differences were found in the objective structured clinical exam, test B, and test C. e-learning exclusively based on clinical cases is an effective method of education in preparation for HT sessions and can reduce attendance time in ultrasound courses.

Arabidopsis basic leucine zipper transcription factors involved in an abscisic acid-dependent signal transduction pathway under drought and high-salinity conditions

PubMed Central

Uno, Yuichi; Furihata, Takashi; Abe, Hiroshi; Yoshida, Riichiro; Shinozaki, Kazuo; Yamaguchi-Shinozaki, Kazuko

2000-01-01

The induction of the dehydration-responsive Arabidopsis gene, rd29B, is mediated mainly by abscisic acid (ABA). Promoter analysis of rd29B indicated that two ABA-responsive elements (ABREs) are required for the dehydration-responsive expression of rd29B as cis-acting elements. Three cDNAs encoding basic leucine zipper (bZIP)-type ABRE-binding proteins were isolated by using the yeast one-hybrid system and were designated AREB1, AREB2, and AREB3 (ABA-responsive element binding protein). Transcription of the AREB1 and AREB2 genes is up-regulated by drought, NaCl, and ABA treatment in vegetative tissues. In a transient transactivation experiment using Arabidopsis leaf protoplasts, both the AREB1 and AREB2 proteins activated transcription of a reporter gene driven by ABRE. AREB1 and AREB2 required ABA for their activation, because their transactivation activities were repressed in aba2 and abi1 mutants and enhanced in an era1 mutant. Activation of AREBs by ABA was suppressed by protein kinase inhibitors. These results suggest that both AREB1 and AREB2 function as transcriptional activators in the ABA-inducible expression of rd29B, and further that ABA-dependent posttranscriptional activation of AREB1 and AREB2, probably by phosphorylation, is necessary for their maximum activation by ABA. Using cultured Arabidopsis cells, we demonstrated that a specific ABA-activated protein kinase of 42-kDa phosphorylated conserved N-terminal regions in the AREB proteins. PMID:11005831

Arabidopsis basic leucine zipper transcription factors involved in an abscisic acid-dependent signal transduction pathway under drought and high-salinity conditions.

PubMed

Uno, Y; Furihata, T; Abe, H; Yoshida, R; Shinozaki, K; Yamaguchi-Shinozaki, K

2000-10-10

The induction of the dehydration-responsive Arabidopsis gene, rd29B, is mediated mainly by abscisic acid (ABA). Promoter analysis of rd29B indicated that two ABA-responsive elements (ABREs) are required for the dehydration-responsive expression of rd29B as cis-acting elements. Three cDNAs encoding basic leucine zipper (bZIP)-type ABRE-binding proteins were isolated by using the yeast one-hybrid system and were designated AREB1, AREB2, and AREB3 (ABA-responsive element binding protein). Transcription of the AREB1 and AREB2 genes is up-regulated by drought, NaCl, and ABA treatment in vegetative tissues. In a transient transactivation experiment using Arabidopsis leaf protoplasts, both the AREB1 and AREB2 proteins activated transcription of a reporter gene driven by ABRE. AREB1 and AREB2 required ABA for their activation, because their transactivation activities were repressed in aba2 and abi1 mutants and enhanced in an era1 mutant. Activation of AREBs by ABA was suppressed by protein kinase inhibitors. These results suggest that both AREB1 and AREB2 function as transcriptional activators in the ABA-inducible expression of rd29B, and further that ABA-dependent posttranscriptional activation of AREB1 and AREB2, probably by phosphorylation, is necessary for their maximum activation by ABA. Using cultured Arabidopsis cells, we demonstrated that a specific ABA-activated protein kinase of 42-kDa phosphorylated conserved N-terminal regions in the AREB proteins.

Thermal barrier coating having high phase stability

DOEpatents

Subramanian, Ramesh

2002-01-01

A device (10) comprising a substrate (22) having a deposited ceramic thermal barrier coating characterized by a microstructure having gaps (28) where the thermal barrier coating comprises a first thermal barrier layer (40), and a second thermal barrier layer (30) with a pyrochlore crystal structure having a chemical formula of A.sup.n+.sub.2-x B.sup.m+.sub.2+x O.sub.7-y, where A is selected from the group of elements consisting of La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, and mixtures thereof, where B is selected from the group of elements consisting of Zr, Hf, Ti and mixtures thereof, where n and m are the valence of A and B respectively, and for -0.5.ltoreq.x.ltoreq.0.5, ##EQU1## and excluding the following combinations for x=0, y=0: A=La and B=Zr; A=La and B=Hf; A=Gd and B=Hf; and A=Yb and B=Ti.

A two dimensional interface element for coupling of independently modeled three dimensional finite element meshes and extensions to dynamic and non-linear regimes

NASA Technical Reports Server (NTRS)

Aminpour, Mohammad

1995-01-01

The work reported here pertains only to the first year of research for a three year proposal period. As a prelude to this two dimensional interface element, the one dimensional element was tested and errors were discovered in the code for built-up structures and curved interfaces. These errors were corrected and the benchmark Boeing composite crown panel was analyzed successfully. A study of various splines led to the conclusion that cubic B-splines best suit this interface element application. A least squares approach combined with cubic B-splines was constructed to make a smooth function from the noisy data obtained with random error in the coordinate data points of the Boeing crown panel analysis. Preliminary investigations for the formulation of discontinuous 2-D shell and 3-D solid elements were conducted.

Physical Therapists’ Perceptions of Knowledge and Clinical Behavior Regarding Cardiovascular Disease Prevention

PubMed Central

Van Zant, R Scott; Cape, Kelly Jo; Roach, Katrina; Sweeney, Janie

2013-01-01

Purpose The study purpose was to assess perceptions of physical therapists (PTs) regarding the role of physical therapy in cardiovascular disease (CVD) prevention. Methods A 25-item survey, validated by expert cardiovascular/pulmonary (CVP) PTs, was sent electronically to 2,673 PTs. Each item represented an element of clinical practice behavior: education of CVD/risk factors (EDCVD), administration of primary CVD prevention (PRECVD), identifying underlying CVD/risk factors (IDCVD), monitoring CV status in patients with CVD (MONCVD). Responses were assigned numeric values (strongly agree = 5 to strongly disagree = 1), and mean element scores were analyzed. Results Most of the 516 respondents were APTA Section members (34% CVP Section, 42% other Section membership) and worked in academia (53%). Items showing a high (> 95%) level of agreement included patient education of smoking (97%) and monitoring exercise intensity (99%), assessing exercise benefits (99%), clinically identifying obesity (97%) and hypertension (97%), and monitoring CV response to exercise (99%). Items failing to reach 80% overall agreement were patient education of CVD medications (79%) and blood chemistry (72%), and assessing CVD family history (75%), patient BMI (60%), and body composition (33%). Identifying underlying CVD (77.2%) was the only practice behavior failing to reach 80% agreement. Outpatient PTs agreed significantly less to all elements vs. academics, and to IDCVD vs. all PTs except home health. Conclusions Physical therapists support most CVD prevention behaviors, but not given elements of patient education and identifying underlying CVD/risk factors. PMID:23801901

Health Education Telecommunications Experiment

NASA Technical Reports Server (NTRS)

Whalen, A. A.

1975-01-01

The Health/Education Telecommunications Experiment carried out with Applications Technology Satellite-6 is described. The experiment tested the effectiveness of color television broadcasts to over 120 low-cost receivers in rural areas. Five types of earth stations were involved: receive-only terminals (ROT), an intensive terminal consisting of the ROT plus a VHF transmitter and receiver; comprehensive S and C-band terminals having the capability of transmitting the video signal plus four audio channels; and the main originating stations. Additional supporting elements comprise 120 video receive terminals, 51 telephony transceivers, and 8 video originating terminals of 3 different parts. Technical parameters were measured to within 1 dB of the calculated values.

Selective oxidation of alkanes and/or alkenes to valuable oxygenates

DOEpatents

Lin, Manhua; Pillai, Krishnan S.

2011-02-15

A catalyst, its method of preparation and its use for producing at least one of methacrolein and methacrylic acid, for example, by subjecting isobutane or isobutylene or a mixture thereof to a vapor phase catalytic oxidation in the presence of air or oxygen. In the case where isobutane alone is subjected to a vapor phase catalytic oxidation in the presence of air or oxygen, the product is at least one of isobutylene, methacrolein and methacrylic acid. The catalyst comprises a compound having the formula A.sub.aB.sub.bX.sub.xY.sub.yZ.sub.zO.sub.o wherein A is one or more elements selected from the group of Mo, W and Zr, B is one or more elements selected from the group of Bi, Sb, Se, and Te, X is one or more elements selected from the group of Al, Bi, Ca, Ce, Co, Fe, Ga, Mg, Ni, Nb, Sn, W and Zn, Y is one or more elements selected from the group of Ag, Au, B, Cr, Cs, Cu, K, La, Li, Mg, Mn, Na, Nb, Ni, P, Pb, Rb, Re, Ru, Sn, Te, Ti, V and Zr, and Z is one or more element from the X or Y groups or from the following: As, Ba, Pd, Pt, Sr, or mixtures thereof, and wherein a=1, 0.05

Quantitative Measurements of the Effects of Variations in Panel Density and Distributions for Panel Method Computer Programs

DTIC Science & Technology

1980-01-01

AND ADDRESS 1 .PROGRAM ELEMENT. PROJECT, TASK AREA & WORK UNIT NUMBERS Aircraft and -.rew Systems Technology Di r. (C:ode 60 E61-.U o A0 Naval Air...0 . . . . . . . . . . . B- 1 B-If Input Statistics For Equations 5 and 6 .... ....... B- 2 B-Ill Computation of Coefficients of...trapezoidal panels and the formula for PAR can be derived for the case where equal spanwise and chordwise divisions are used: PAR (N/2M)/( 1 +X ( 2 = ( 2

...And What Are You Planning to Be When You Grow Up? A Guide for Career Education in the Primary Levels.

ERIC Educational Resources Information Center

Arkansas State Dept. of Education, Little Rock. Career Education Section.

This curriculum guide provides examples of activities a teacher at the primary level can use for any phase of career education being studied. Activities are listed under each of the eight elements of career education: (1) Self Awareness, (2) Educational Awareness, (3) Career Awareness, (4) Economic Awareness, (5) Decision Making, (6) Beginning…

Evaluating the Existing School Plant. Educational Facilities Digest 2.

ERIC Educational Resources Information Center

Piele, Philip; Wright, Darrell

In general, the guides for evaluating existing school buildings list the various elements of the building and its properties. The elements commonly listed include site, which embraces the adequacy of size, location, and natural environment; internal environment, which is commonly divided into space, visual qualities, thermal qualities, and sonic…

School Restructuring: What Works When? A Guide for Education Leaders

ERIC Educational Resources Information Center

Hassel, Emily Ayscue; Hassel, Bryan C.; Arkin, Matthew D.; Kowal, Julie M.; Steiner, Lucy M.

2009-01-01

Studies of high-performing schools, where all students learn more than similar students in other schools, show common design elements. These elements are comprehensive, affecting the whole school, and include: (1) Clear mission guiding daily activities; (2) High, unyielding expectations that all students will learn; (3) Frequent monitoring of…

Data Element Dictionary: Student. Second Edition.

ERIC Educational Resources Information Center

Martin, James S.

This document is intended to serve as a guide for institutions in the development of data bases to support the implementation of planning and management systems. This publication serves to identify and describe those student-related data elements: (1) required to support current National Center for Higher Education Systems (NCHEMS) products; (2)…

Test and Evaluation Enhancements for Cognitive Radio Technologies

DTIC Science & Technology

2015-05-13

SECURITY CLASSIFICATION OF: This document serves as the final report for the Department of Defense (DoD) Research and Education Program for...report will described the instrumentation and the integration into the academic and research programs . All instrumentation has been procured, delivered...UNIT NUMBER 5c. PROGRAM ELEMENT NUMBER 5b. GRANT NUMBER 5a. CONTRACT NUMBER Form Approved OMB NO. 0704-0188 3. DATES COVERED (From - To) - UU UU UU UU

(NANOSAT) The ONYX Nanosatellite Mission

DTIC Science & Technology

2007-05-14

THE ONYX NANOSTATELLITE MISSION 5b. GRANT NUMBER FA9550-05-1-0249 5c. PROGRAM ELEMENT NUMBER 61102F 6. AUTHOR(S) 5d. PROJECT NUMBER PROFESSOR KITTS...never delivered by our partners at the Jet Propulsion Laboratory). Apart from this exception, the ONYX vehicle conformed to all IJNP prototype...the educational experiences offered by the UNP. This report does not attempt to detail the design of or the processes used to develop the ONYX space

Internal loop/bulge and hairpin loop of the iron-responsive element of ferritin mRNA contribute to maximal iron regulatory protein 2 binding and translational regulation in the iso-iron-responsive element/iso-iron regulatory protein family.

PubMed

Ke, Y; Sierzputowska-Gracz, H; Gdaniec, Z; Theil, E C

2000-05-23

Iron-responsive elements (IREs), a natural group of mRNA-specific sequences, bind iron regulatory proteins (IRPs) differentially and fold into hairpins [with a hexaloop (HL) CAGUGX] with helical distortions: an internal loop/bulge (IL/B) (UGC/C) or C-bulge. C-bulge iso-IREs bind IRP2 more poorly, as oligomers (n = 28-30), and have a weaker signal response in vivo. Two trans-loop GC base pairs occur in the ferritin IRE (IL/B and HL) but only one in C-bulge iso-IREs (HL); metal ions and protons perturb the IL/B [Gdaniec et al. (1998) Biochemistry 37, 1505-1512]. IRE function (translation) and physical properties (T(m) and accessibility to nucleases) are now compared for IL/B and C-bulge IREs and for HL mutants. Conversion of the IL/B into a C-bulge by a single deletion in the IL/B or by substituting the HL CG base pair with UA both derepressed ferritin synthesis 4-fold in rabbit reticulocyte lysates (IRP1 + IRP2), confirming differences in IRP2 binding observed for the oligomers. Since the engineered C-bulge IRE was more helical near the IL/B [Cu(phen)(2) resistant] and more stable (T(m) increased) and the HL mutant was less helical near the IL/B (ribonuclease T1 sensitive) and less stable (T(m) decreased), both CG trans-loop base pairs contribute to maximum IRP2 binding and translational regulation. The (1)H NMR spectrum of the Mg-IRE complex revealed, in contrast to the localized IL/B effects of Co(III) hexaammine observed previously, perturbation of the IL/B plus HL and interloop helix. The lower stability and greater helix distortion in the ferritin IL/B-IRE compared to the C-bulge iso-IREs create a combinatorial set of RNA/protein interactions that control protein synthesis rates with a range of signal sensitivities.

Effects of trace elements on the crystal field parameters of Nd ions at the surface of Nd{sub 2}Fe{sub 14}B grains

DOE Office of Scientific and Technical Information (OSTI.GOV)

Toga, Yuta; Suzuki, Tsuneaki; Sakuma, Akimasa, E-mail: sakuma@solid.apph.tohoku.ac.jp

2015-06-14

Using first-principles calculations, we investigate the positional dependence of trace elements such as O and Cu on the crystal field parameter A{sub 2}{sup 0}, proportional to the magnetic anisotropy constant K{sub u} of Nd ions placed at the surface of Nd{sub 2}Fe{sub 14}B grains. The results suggest the possibility that the A{sub 2}{sup 0} parameter of Nd ions at the (001) surface of Nd{sub 2}Fe{sub 14}B grains exhibits a negative value when the O or Cu atom is located near the surface, closer than its equilibrium position. At the (110) surface, however, O atoms located at the equilibrium position providemore » a negative A{sub 2}{sup 0}, while for Cu additions A{sub 2}{sup 0} remains positive regardless of Cu's position. Thus, Cu atoms are expected to maintain a positive local K{sub u} of surface Nd ions more frequently than O atoms when they approach the grain surfaces in the Nd-Fe-B grains.« less

Engaging Students in Integrated Ethics Education: A Communication in the Disciplines Study of Pedagogy and Students' Roles in Society

ERIC Educational Resources Information Center

Canary, Heather E.; Taylor, Julie L.; Herkert, Joseph R.; Ellison, Karin; Wetmore, Jameson M.; Tarin, Carlos A.

2014-01-01

In this quasi-experimental study, we investigated two elements of ethics education: (1) how participating in ethics education influenced science and engineering graduate students' views of their roles in society, and (2) what students found most valuable and relevant. Participants were 98 graduate science and engineering students. Qualitative…

Effectiveness of nutrition education, iron supplementation or both on iron status in children.

PubMed

Kapur, D; Sharma, S; Agarwal, K N

2003-12-01

A community-based, randomized trial was designed to compare the effect of nutrition education and/or iron supplementation (weekly) on iron status of children in an urban slum in Delhi. Four hundred and fifty one children, 9-36 months of age and their caretakers (mothers), assigned to one of the following groups were included in the cohort. Group 1, nutrition education. Group 2, supplementation (with 20 mg elemental iron). Group 3, nutrition education with supplementation (with 20 mg elemental iron) and Group 4, control given placebo. The intervention program was of four months duration, with a treatment phase of 8 wk followed by 8 wk of no treatment. Post intervention, at 8 wk and at 16 wk, the hemoglobin change in the nutrition education, supplementation, nutrition education with supplementation and control groups was 2.9, 1.9, 3.8 and -5.9%, respectively and 2.1, -1.9, 0 and -9.3%, respectively (as compared to initial values). There was no significant effect of any of the intervention at 8 weeks. At 16 wk, there was significant positive effect of nutrition education group (p less than 0.05). The percent change in serum ferritin value at 16 wk in the nutrition education, supplementation, nutrition education with supplementation and control groups was 5.7, -2.3, -3.4 and -40%, respectively. Serum ferritin values were significantly higher for the nutrition education group (p < 0.001) as compared to the control. At 16 wk, the nutrition education group mothers showed significantly higher nutrition knowledge and the dietary iron intake of children was significantly higher than their control group counterparts (p < 0.0001). The study suggests that nutrition education did have a positive effect on the iron status possibly by improving the dietary iron intake.

Genome-wide analysis identifies chickpea (Cicer arietinum) heat stress transcription factors (Hsfs) responsive to heat stress at the pod development stage.

PubMed

Chidambaranathan, Parameswaran; Jagannadham, Prasanth Tej Kumar; Satheesh, Viswanathan; Kohli, Deshika; Basavarajappa, Santosh Halasabala; Chellapilla, Bharadwaj; Kumar, Jitendra; Jain, Pradeep Kumar; Srinivasan, R

2018-05-01

The heat stress transcription factors (Hsfs) play a prominent role in thermotolerance and eliciting the heat stress response in plants. Identification and expression analysis of Hsfs gene family members in chickpea would provide valuable information on heat stress responsive Hsfs. A genome-wide analysis of Hsfs gene family resulted in the identification of 22 Hsf genes in chickpea in both desi and kabuli genome. Phylogenetic analysis distinctly separated 12 A, 9 B, and 1 C class Hsfs, respectively. An analysis of cis-regulatory elements in the upstream region of the genes identified many stress responsive elements such as heat stress elements (HSE), abscisic acid responsive element (ABRE) etc. In silico expression analysis showed nine and three Hsfs were also expressed in drought and salinity stresses, respectively. Q-PCR expression analysis of Hsfs under heat stress at pod development and at 15 days old seedling stage showed that CarHsfA2, A6, and B2 were significantly upregulated in both the stages of crop growth and other four Hsfs (CarHsfA2, A6a, A6c, B2a) showed early transcriptional upregulation for heat stress at seedling stage of chickpea. These subclasses of Hsfs identified in this study can be further evaluated as candidate genes in the characterization of heat stress response in chickpea.

Information Summary, Area of Concern: Grand Calumet River, Indiana

DTIC Science & Technology

1991-03-01

Indiana Harbor and Adjacent Lake Michigan (Source Rl, Table 4) 10 Concentrations of 26 Major, Minor and Trace Elements in Sediments from Indiana Harbor...2 Dec 84 (Source R39, Table 2) 68 Concentrations of Major, Minor , and Trace Elements in Fish and Crayfish from Indiana Harbor and Adjacent Lake...Table 21b) 71 Catch per Unit Effort in Crayfish Traps (Source Rl, Table 21c) 72 Concentratiors of Major, Minor , and Trace Elements in Periphyton and

The discovery of Ni V in the photospheres of the hot DA white dwarfs RE 2214-492 and G191-B2B

NASA Technical Reports Server (NTRS)

Holberg, J. B.; Hubeny, I.; Barstow, M. A.; Lanz, T.; Sion, E. M.; Tweedy, R. W.

1994-01-01

We have co-added six recently obtained International Ultraviolet Explorer (IUE) echelle spectra of the hot DA white dwarf RE 2214-492 and 10 existing archive spectra of the well-known hot DA, G191-B2B. We find that both stars contain numerous weak features due to Ni V. Nickel is thus the second iron-group element to be found in the spectra of the very hottest DA white dwarfs. In addition to Ni V, we also observe Al III in both stars and present evidence for the possible presence of Ni IV and Fe IV in RE 2214-492. The presence of Ni and Al, together with previously reported elements, will contribute significantly to both the EUV opacity and to the apparent complexity of the UV spectra of these stars. Using Non-Local Thermodynamic Equilibrium (NLTE) model atmospheres we estimate the Ni abundances in RE 2214-492 the G191-B2B to be log(Ni/H) = -5.5 +/- 0.3 and -6.0 +/- 0.3, respectively.

Uranium hydrogeochemical and stream sediment reconnaissance of the Cortez NTMS Quadrangle, Colorado/Utah, including concentrations of forty-three additional elements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Warren, R.G.

1979-05-01

During the summers of 1976, 1977, and 1978, 598 water and 1657 sediment samples were collected from 1775 locations within the 19,600-km/sup 2/ area of the Cortez Quadrangle, Colorado and Utah. Water samples were collected from streams, springs, and wells; sediment samples were collected from stream channels (wet and dry) and from springs. Each water sample was analyzed for 13 elements, and each sediment sample was analyzed for 43 elements. Uranium concentrations in water samples range from below the detection limit of 0.02 to 241.47 ppB and have a median of 0.87 ppB and a mean of 3.80 ppB. Backgroundmore » uranium concentrations are 2 to 5 ppB in several nonmountainous regions but are much lower in mountainous areas, particularly in the northeastern portion of the quadrangle. Water samples containing high uranium concentrations (>20 ppB) generally are associated with high conductivities, high concentrations of other metallic elements, and geologic units, such as the Mancos shale, that are unfavorable for uranium mineralization. However, four ground-water samples exhibit high uranium concentrations without concomitant high conductivities or high concentrations of other metallic elements. Two of these samples were collected from sites in the Slick Rock U--V district, and two were collected in the Morrison formation in the southern portion of the quadrangle where large uranium deposits are not known. Water samples collected from the northwestern corner of the quadrangle uniformly exhibit background uranium values but generally contain high nickel concentrations. In this area, U--Cu (White Canyon-type) deposits are hosted primarily by the Shinarump member of the Chinle formation. Uranium concentrations in sediment samples range from 0.51 to 76.41 ppM and have a median of 2.76 ppM and a mean of 3.08 ppM. Background uranium and metallic element concentrations decrease to the southwest from the highest values in the northeastern portion of the quadrangle.« less

Insertion Demonstrations of Digital Gallium Arsenide. OBP-80 Final Technical Report. Volume 1. Chip Set Schematics

DTIC Science & Technology

1992-01-01

In First Out FMEA Failure Mode Effects Analysis EDM Engineering Development Model GALU Generic Arithmetic Logic Unit GaAs Gallium Arsenide GTE Ground...Bl B>55 * 1585/IS1/B1 = B56 I$11146/I$3/B1 B= 57 I$2S146/I$2/B1 B= 58 * $1146/1$1/81 =>B59 * 1590/IS3/Bl B= 60 *1$590/IS2/Bl== B61 * 1590/IS1/B1 - B62...vote circuitry. It is known that only 60 fC of charge is needed to upset the latch elements. It is interesting to speculate how much charge is required

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bazavov, A.; Bernard, C.; Bouchard, C. M.

We calculate—for the first time in three-flavor lattice QCD—the hadronic matrix elements of all five local operators that contribute to neutral B 0- and B s-meson mixing in and beyond the Standard Model. We present a complete error budget for each matrix element and also provide the full set of correlations among the matrix elements. We also present the corresponding bag parameters and their correlations, as well as specific combinations of the mixing matrix elements that enter the expression for the neutral B-meson width difference. We obtain the most precise determination to date of the SU(3)-breaking ratio ξ=1.206(18)(6), where themore » second error stems from the omission of charm-sea quarks, while the first encompasses all other uncertainties. The threefold reduction in total uncertainty, relative to the 2013 Flavor Lattice Averaging Group results, tightens the constraint from B mixing on the Cabibbo-Kobayashi-Maskawa (CKM) unitarity triangle. Our calculation employs gauge-field ensembles generated by the MILC Collaboration with four lattice spacings and pion masses close to the physical value. We use the asqtad-improved staggered action for the light-valence quarks and the Fermilab method for the bottom quark. We use heavy-light meson chiral perturbation theory modified to include lattice-spacing effects to extrapolate the five matrix elements to the physical point. We combine our results with experimental measurements of the neutral B-meson oscillation frequencies to determine the CKM matrix elements |V td| = 8.00(34)(8)×10 -3, |V ts| = 39.0(1.2)(0.4)×10 -3, and |V td/V ts| = 0.2052(31)(10), which differ from CKM-unitarity expectations by about 2σ. In addition, these results and others from flavor-changing-neutral currents point towards an emerging tension between weak processes that are mediated at the loop and tree levels.« less

Correction of murine Rag2 severe combined immunodeficiency by lentiviral gene therapy using a codon-optimized RAG2 therapeutic transgene.

PubMed

van Til, Niek P; de Boer, Helen; Mashamba, Nomusa; Wabik, Agnieszka; Huston, Marshall; Visser, Trudi P; Fontana, Elena; Poliani, Pietro Luigi; Cassani, Barbara; Zhang, Fang; Thrasher, Adrian J; Villa, Anna; Wagemaker, Gerard

2012-10-01

Recombination activating gene 2 (RAG2) deficiency results in severe combined immunodeficiency (SCID) with complete lack of T and B lymphocytes. Initial gammaretroviral gene therapy trials for other types of SCID proved effective, but also revealed the necessity of safe vector design. We report the development of lentiviral vectors with the spleen focus forming virus (SF) promoter driving codon-optimized human RAG2 (RAG2co), which improved phenotype amelioration compared to native RAG2 in Rag2(-/-) mice. With the RAG2co therapeutic transgene, T-cell receptor (TCR) and immunoglobulin repertoire, T-cell mitogen responses, plasma immunoglobulin levels and T-cell dependent and independent specific antibody responses were restored. However, the thymus double positive T-cell population remained subnormal, possibly due to the SF virus derived element being sensitive to methylation/silencing in the thymus, which was prevented by replacing the SF promoter by the previously reported silencing resistant element (ubiquitous chromatin opening element (UCOE)), and also improved B-cell reconstitution to eventually near normal levels. Weak cellular promoters were effective in T-cell reconstitution, but deficient in B-cell reconstitution. We conclude that immune functions are corrected in Rag2(-/-) mice by genetic modification of stem cells using the UCOE driven codon-optimized RAG2, providing a valid optional vector for clinical implementation.

34 CFR 5.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

.... 552. (b) Department means the United States Department of Education. (c) Component means each separate... 34 Education 1 2014-07-01 2014-07-01 false Definitions. 5.2 Section 5.2 Education Office of the Secretary, Department of Education AVAILABILITY OF INFORMATION TO THE PUBLIC General Provisions § 5.2...

Some Adult Educational Elements in Ancient Eastern Education.

ERIC Educational Resources Information Center

MacGregor, Norman

The existence of adult educational elements in acient India, China, Judea, and Arabia is demonstrated in this paper. Hindu and Buddhist adult education is discussed first, followed by Chinese adult education, Jewish adult education, and Islamic adult education. Conclusions of the study on which this paper reports are: (1) the existence of the…

Distribution trends and influence of 4d transition metal elements (Ru, Rh and Pd) doping on mechanical properties and martensitic transformation temperature of B2-ZrCu phase

NASA Astrophysics Data System (ADS)

Guo, Fuda; Zhan, Yongzhong

2017-12-01

The prediction for distribution trends and effect of three 4d transition metal elements (Ru, Rh and Pd) on mechanical properties and martensitic transformation temperature of B2-ZrCu phase were investigated by first-principles calculations. The convex surface of formation energy suggests that the alloying elements prefer to occupy the Cu sites in B2-ZrCu phase and the dopants studied in present are able to strengthen the phase stability. The calculated results of substitutional formation energy suggest that the distribution trend of dopants in B2-ZrCu phase is Ru > Rh > Pd below the dopant concentration 9 at. %, and the distribution trend is Rh > Pd > Ru from 9 at. % to 12.5 at. %. The elastic constants and mechanical properties including bulk modulus and shear modulus were calculated and discussed. The brittleness/ductility characteristic was investigated using the B/G ratio, Poisson's ratio v and Cauchy pressure Cp. The martensitic transformation temperature (Ms) and melting point (Tm) were predicted by using two cubic elastic moduli (C‧ and C44). The prediction results suggest that only the Ms of Zr8Cu7Pd is higher than the parent. The martensitic transformation temperatures of other compounds decrease with the addition of 4d transition metal dopants. Finally, the electronic structures and electron density different were discussed to reveal the bonding characteristics.

Finite Element Analysis of ASTOVL Fighter Structure

DTIC Science & Technology

1991-12-01

SEQGP 2093 10061 2082 10062 2094 10063 2083 10064 $SEQGP 2084 10065 2085 10066 2086 10067 2087 10068 $SEQGP 2088 10069 2089 10070 209L 10071 2114...CB4658 456 $:+CBAR-PA ------ PB ------ WIA ---- W2A ---- W3A ---- WIB ---- W2B ---- W3B ---- $ $:CQUAD4-EID ---- PID ----- GI ------ G2 ------ G3

Identification of an active ID-like group of SINEs in the mouse

PubMed Central

Kass, David H; Jamison, Nicole

2007-01-01

The mouse genome consists of five known families of SINEs: B1, B2, B4/RSINE, ID, and MIR. Using RT-PCR we identified a germ-line transcript that demonstrates 92.7% sequence identity to ID (excluding primer sequence), yet a BLAST search identified numerous matches of 100% sequence identity. We analyzed four of these elements for their presence in orthologous genes in strains and subspecies of M. musculus as well as other species of Mus using a PCR-based assay. All four analyzed elements were either identified only in M. musculus or exclusively in both M. musculus and M. domesticus indicative of recent integrations. In conjunction with the identification of transcripts, we present an active ID-like group of elements that is not derived from the proposed BC1 master gene of ID elements. A BLAST of the rat genome indicated that these elements were not in the rat. Therefore, this family of SINEs has recently evolved, and since thus far has mainly been observed in M. musculus, we then refer to this family as MMIDL. PMID:17572061

Identification of an active ID-like group of SINEs in the mouse.

PubMed

Kass, David H; Jamison, Nicole

2007-09-01

The mouse genome consists of five known families of SINEs: B1, B2, B4/RSINE, ID, and MIR. Using RT-PCR we identified a germ-line transcript that demonstrates 92.7% sequence identity to ID (excluding primer sequence), yet a BLAST search identified numerous matches of 100% sequence identity. We analyzed four of these elements for their presence in orthologous genes in strains and subspecies of Mus musculus as well as other species of Mus using a PCR-based assay. All four analyzed elements were identified either only in M. musculus or exclusively in both M. musculus and M. domesticus, indicative of recent integrations. In conjunction with the identification of transcripts, we present an active ID-like group of elements that is not derived from the proposed BC1 master gene of ID elements. A BLAST of the rat genome indicated that these elements were not in the rat. Therefore, this family of SINEs has recently evolved, and since it has thus far been observed mainly in M. musculus, we refer to this family as MMIDL.

Biennial Survey of Education in the United States, 1934-1936. Bulletin, 1937, No. 2. Volume I. Chapter X: Developments in Educational Method, 1934-36

ERIC Educational Resources Information Center

Davis, Mary Dabney; Everard, L. C.; Koon, Cline M.; Lathrop, Edith A.; Proffitt, Maris M.; Segel, David

1937-01-01

This report presents a series of brief surveys of recent developments in educational method. It points to the growing conviction that many of the aids and services once regarded as mere accessories to educational method are now among its essential elements. In the first review presented herein, Maris Profitt recognizes the present widespread…

Toward an improved determination of Earth's lithospheric magnetic field from satellite observations

NASA Astrophysics Data System (ADS)

Kotsiaros, S.

2016-12-01

An analytical and numerical analysis of the spectral properties of the gradient tensor, initially performed by Rummel and van Gelderen (1992) for the gravity potential, shows that when the tensor elements are grouped into sets of semi-tangential and pure-tangential parts, they produce almost identical signal content as the normal element. Moreover, simple eigenvalue relations can be derived between these sets and the spherical harmonic expansion of the potential. This theoretical development generally applies to any potential field. First, the analysis of Rummel and van Gelderen (1992) is adapted to the magnetic field case and then the elements of the magnetic gradient tensor are estimated by 2 years of Swarm data and grouped into Γ(1) = {[∇B]rθ,[∇B]rφ} resp. Γ(2) = {[∇B]θθ-[∇B]φφ, 2[∇B]θφ}. It is shown that the estimated combinations Γ(1) and Γ(2) produce similar signal content as the theoretical radial gradient [∇B]rr. These results demonstrate the ability of multi-satellite missions such as Swarm, which cannot directly measure the radial gradient, to retrieve similar signal content by means of the horizontal gradients. Finally, lithospheric field models are derived using the gradient combinations Γ(1) and Γ(2) and compared with models derived from traditional vector and gradient data. The model resulting from Γ(1) leads to a very similar, and in particular cases improved, model compared to models retrieved by using approximately three times more data, i.e. a full set of vector, North-South and East-West gradients. ReferencesRummel, R., and M. van Gelderen (1992), Spectral analysis of the full gravity tensor, Geophysical Journal International, 111 (1), 159-169.

The site-specific ribosomal DNA insertion element R1Bm belongs to a class of non-long-terminal-repeat retrotransposons.

PubMed Central

Xiong, Y; Eickbush, T H

1988-01-01

Two types of insertion elements, R1 and R2 (previously called type I and type II), are known to interrupt the 28S ribosomal genes of several insect species. In the silkmoth, Bombyx mori, each element occupies approximately 10% of the estimated 240 ribosomal DNA units, while at most only a few copies are located outside the ribosomal DNA units. We present here the complete nucleotide sequence of an R1 insertion from B. mori (R1Bm). This 5.1-kilobase element contains two overlapping open reading frames (ORFs) which together occupy 88% of its length. ORF1 is 461 amino acids in length and exhibits characteristics of retroviral gag genes. ORF2 is 1,051 amino acids in length and contains homology to reverse transcriptase-like enzymes. The analysis of 3' and 5' ends of independent isolates from the ribosomal locus supports the suggestion that R1 is still functioning as a transposable element. The precise location of the element within the genome implies that its transposition must occur with remarkable insertion sequence specificity. Comparison of the deduced amino acid sequences from six retrotransposons, R1 and R2 of B. mori, I factor and F element of Drosophila melanogaster, L1 of Mus domesticus, and Ingi of Trypanosoma brucei, reveals a relatively high level of sequence homology in the reverse transcriptase region. Like R1, these elements lack long terminal repeats. We have therefore named this class of related elements the non-long-terminal-repeat (non-LTR) retrotransposons. Images PMID:2447482

A Ramie bZIP Transcription Factor BnbZIP2 Is Involved in Drought, Salt, and Heavy Metal Stress Response.

PubMed

Huang, Chengjian; Zhou, Jinghua; Jie, Yucheng; Xing, Hucheng; Zhong, Yingli; Yu, Weilin; She, Wei; Ma, Yushen; Liu, Zehang; Zhang, Ying

2016-12-01

bZIP transcription factors play key roles in plant growth, development, and stress signaling. A bZIP gene BnbZIP2 (GenBank accession number: KP642148) was cloned from ramie. BnbZIP2 has a 1416 base pair open reading frame, encoding a 471 amino acid protein containing a characteristic bZIP domain and a leucine zipper. BnbZIP2 shares high sequence similarity with bZIP factors from other plants. The BnbZIP2 protein is localized to both nuclei and cytoplasm. Transcripts of BnbZIP2 were found in various tissues in ramie, with significantly higher levels in female and male flowers. Its expression was induced by drought, high salinity, and abscisic acid treatments. Analysis of the cis-elements in promoters of BnbZIP2 identified cis-acting elements involved in growth, developmental processes, and a variety of stress responses. Transgenic Arabidopsis plants' overexpression of BnbZIP2 exhibited more sensitivity to drought and heavy metal Cd stress during seed germination, whereas more tolerance to high-salinity stress than the wild type during both seed germination and plant development. Thus, BnbZIP2 may act as a positive regulator in plants' response to high-salinity stress and be an important candidate gene for molecular breeding of salt-tolerant plants.

LiBSi2: a tetrahedral semiconductor framework from boron and silicon atoms bearing lithium atoms in the channels.

PubMed

Zeilinger, Michael; van Wüllen, Leo; Benson, Daryn; Kranak, Verina F; Konar, Sumit; Fässler, Thomas F; Häussermann, Ulrich

2013-06-03

Silicon swallows up boron: The novel open tetrahedral framework structure (OTF) of the Zintl phase LiBSi2 was made by applying high pressure to a mixture of LiB and elemental silicon. The compound represents a new topology in the B-Si net (called tum), which hosts Li atoms in the channels (see picture). LiBSi2 is the first example where B and Si atoms form an ordered common framework structure with B engaged exclusively in heteronuclear B-Si contacts.

29 CFR Appendix V to Part 1918 - Basic Elements of a First Aid Training Program (Non-mandatory)

Code of Federal Regulations, 2011 CFR

2011-07-01

...-mandatory) V Appendix V to Part 1918 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND...) Side Stress on Boom .66(b)(3)(i) Vessel's Permanent Equipment .55 Visible Defects .66(b)(3)(ii) Cups... Related Employments .2 River Towboat .2 Small Trimming Hatch .2 Vessel .2 Vessel's Cargo Handling Gear .2...

29 CFR Appendix V to Part 1918 - Basic Elements of a First Aid Training Program (Non-mandatory)

Code of Federal Regulations, 2012 CFR

2012-07-01

...-mandatory) V Appendix V to Part 1918 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND...) Side Stress on Boom .66(b)(3)(i) Vessel's Permanent Equipment .55 Visible Defects .66(b)(3)(ii) Cups... Related Employments .2 River Towboat .2 Small Trimming Hatch .2 Vessel .2 Vessel's Cargo Handling Gear .2...

A Comparison of the Optimization and Analysis of Doubly Curved Shells Using MSC/NASTRAN and ASTROS

DTIC Science & Technology

1990-12-01

BMC(7,5)=I.OD+00 CALL BMAT (X1,RI,X2,R2,0.OD+00,B,DL) CALL EMAT(DNU,E,T,G) C C DO BMC*E*B C DO 100 J1=1,7 DO 100 J2=1,5 DO 100 J3=1,5 DO 100 J4=1,6...ELEMENT LENGTH. C SUBROUTINE BMAT (XI,RI,X2,R2,DKSI,B,DL) DOUBLE PRECISION XI,RI,X2,R2,DKSI,B(S,6),DL,R,PHI,CPR,SPR,R, &DKMDKP, DLINV C C EXPLANATION OF

Genome-wide mapping of infection-induced SINE RNAs reveals a role in selective mRNA export.

PubMed

Karijolich, John; Zhao, Yang; Alla, Ravi; Glaunsinger, Britt

2017-06-02

Short interspersed nuclear elements (SINEs) are retrotransposons evolutionarily derived from endogenous RNA Polymerase III RNAs. Though SINE elements have undergone exaptation into gene regulatory elements, how transcribed SINE RNA impacts transcriptional and post-transcriptional regulation is largely unknown. This is partly due to a lack of information regarding which of the loci have transcriptional potential. Here, we present an approach (short interspersed nuclear element sequencing, SINE-seq), which selectively profiles RNA Polymerase III-derived SINE RNA, thereby identifying transcriptionally active SINE loci. Applying SINE-seq to monitor murine B2 SINE expression during a gammaherpesvirus infection revealed transcription from 28 270 SINE loci, with ∼50% of active SINE elements residing within annotated RNA Polymerase II loci. Furthermore, B2 RNA can form intermolecular RNA-RNA interactions with complementary mRNAs, leading to nuclear retention of the targeted mRNA via a mechanism involving p54nrb. These findings illuminate a pathway for the selective regulation of mRNA export during stress via retrotransposon activation. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

Genome-wide mapping of infection-induced SINE RNAs reveals a role in selective mRNA export

PubMed Central

Zhao, Yang; Alla, Ravi

2017-01-01

Abstract Short interspersed nuclear elements (SINEs) are retrotransposons evolutionarily derived from endogenous RNA Polymerase III RNAs. Though SINE elements have undergone exaptation into gene regulatory elements, how transcribed SINE RNA impacts transcriptional and post-transcriptional regulation is largely unknown. This is partly due to a lack of information regarding which of the loci have transcriptional potential. Here, we present an approach (short interspersed nuclear element sequencing, SINE-seq), which selectively profiles RNA Polymerase III-derived SINE RNA, thereby identifying transcriptionally active SINE loci. Applying SINE-seq to monitor murine B2 SINE expression during a gammaherpesvirus infection revealed transcription from 28 270 SINE loci, with ∼50% of active SINE elements residing within annotated RNA Polymerase II loci. Furthermore, B2 RNA can form intermolecular RNA–RNA interactions with complementary mRNAs, leading to nuclear retention of the targeted mRNA via a mechanism involving p54nrb. These findings illuminate a pathway for the selective regulation of mRNA export during stress via retrotransposon activation. PMID:28334904

Transcriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacetylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B-cell Acute Lymphoblastic Leukemia*

PubMed Central

Wang, Haijun; Song, Chunhua; Ding, Yali; Pan, Xiaokang; Ge, Zheng; Tan, Bi-Hua; Gowda, Chandrika; Sachdev, Mansi; Muthusami, Sunil; Ouyang, Hongsheng; Lai, Liangxue; Francis, Olivia L.; Morris, Christopher L.; Abdel-Azim, Hisham; Dorsam, Glenn; Xiang, Meixian; Payne, Kimberly J.; Dovat, Sinisa

2016-01-01

Impaired function of the Ikaros (IKZF1) protein is associated with the development of high-risk B-cell precursor acute lymphoblastic leukemia (B-ALL). The mechanisms of Ikaros tumor suppressor activity in leukemia are unknown. Ikaros binds to the upstream regulatory elements of its target genes and regulates their transcription via chromatin remodeling. Here, we report that Ikaros represses transcription of the histone H3K4 demethylase, JARID1B (KDM5B). Transcriptional repression of JARID1B is associated with increased global levels of H3K4 trimethylation. Ikaros-mediated repression of JARID1B is dependent on the activity of the histone deacetylase, HDAC1, which binds to the upstream regulatory element of JARID1B in complex with Ikaros. In leukemia, JARID1B is overexpressed, and its inhibition results in cellular growth arrest. Ikaros-mediated repression of JARID1B in leukemia is impaired by pro-oncogenic casein kinase 2 (CK2). Inhibition of CK2 results in increased binding of the Ikaros-HDAC1 complex to the promoter of JARID1B, with increased formation of trimethylated histone H3 lysine 27 and decreased histone H3 Lys-9 acetylation. In cases of high-risk B-ALL that carry deletion of one Ikaros (IKZF1) allele, targeted inhibition of CK2 restores Ikaros binding to the JARID1B promoter and repression of JARID1B. In summary, the presented data suggest a mechanism through which Ikaros and HDAC1 regulate the epigenetic signature in leukemia: via regulation of JARID1B transcription. The presented data identify JARID1B as a novel therapeutic target in B-ALL and provide a rationale for the use of CK2 inhibitors in the treatment of high-risk B-ALL. PMID:26655717

Position-specific isotope modeling of organic micropollutants transformations through different reaction pathways

NASA Astrophysics Data System (ADS)

Jin, Biao; Rolle, Massimo

2016-04-01

Organic compounds are produced in vast quantities for industrial and agricultural use, as well as for human and animal healthcare [1]. These chemicals and their metabolites are frequently detected at trace levels in fresh water environments where they undergo degradation via different reaction pathways. Compound specific stable isotope analysis (CSIA) is a valuable tool to identify such degradation pathways in different environmental systems. Recent advances in analytical techniques have promoted the fast development and implementation of multi-element CSIA. However, quantitative frameworks to evaluate multi-element stable isotope data and incorporating mechanistic information on the degradation processes [2,3] are still lacking. In this study we propose a mechanism-based modeling approach to simultaneously evaluate concentration as well as bulk and position-specific multi-element isotope evolution during the transformation of organic micropollutants. The model explicitly simulates position-specific isotopologues for those atoms that experience isotope effects and, thereby, provides a mechanistic description of isotope fractionation occurring at different molecular positions. We validate the proposed approach with the concentration and multi-element isotope data of three selected organic micropollutants: dichlorobenzamide (BAM), isoproturon (IPU) and diclofenac (DCF). The model precisely captures the dual element isotope trends characteristic of different reaction pathways and their range of variation consistent with observed multi-element (C, N) bulk isotope fractionation. The proposed approach can also be used as a tool to explore transformation pathways in scenarios for which position-specific isotope data are not yet available. [1] Schwarzenbach, R.P., Egli, T., Hofstetter, T.B., von Gunten, U., Wehrli, B., 2010. Global Water Pollution and Human Health. Annu. Rev. Environ. Resour. doi:10.1146/annurev-environ-100809-125342. [2] Jin, B., Haderlein, S.B., Rolle, M., 2013. Integrated carbon and chlorine isotope modeling: Applications to chlorinated aliphatic hydrocarbons dechlorination. Environ. Sci. Technol. 47, 1443-1451. doi:10.1021/es304053h. [3] Jin, B., Rolle, M., 2014. Mechanistic approach to multi-element isotope modeling of organic contaminant degradation. Chemosphere 95, 131-139. doi:10.1016/j.chemosphere.2013.08.050.

Quality, Social Justice and Accountability--Crucial Determinants of Excellence in Education

ERIC Educational Resources Information Center

Rossouw, J. P.

2015-01-01

Internationally, the quality of education, social justice and accountability can be regarded as key elements of successful school systems and societies. Separately or jointly, these elements can be analysed and debated as distinct fields of study, and linked to an education system to determine the success thereof. Being a pivotal element of…

40 CFR 35.515 - Evaluation of performance.

Code of Federal Regulations, 2010 CFR

2010-07-01

....515 Evaluation of performance. (a) Joint evaluation process. The applicant and the Regional... work plan (see section 35.507(b)(2)(iv)). A description of the evaluation process and reporting... annually and must satisfy the requirements for progress reporting under 40 CFR 31.40(b). (b) Elements of...

Regulation of the plasma cell transcription factor Blimp-1 gene by Bach2 and Bcl6.

PubMed

Ochiai, Kyoko; Muto, Akihiko; Tanaka, Hiromu; Takahashi, Shinichiro; Igarashi, Kazuhiko

2008-03-01

B lymphocyte-induced maturation protein 1 (Blimp-1) is a key regulator for plasma cell differentiation. Prior to the terminal differentiation into plasma cells, Blimp-1 expression is suppressed in B cells by transcription repressors BTB and CNC homology 2 (Bach2) and B cell lymphoma 6 (Bcl6). Bach2 binds to the Maf recognition element (MARE) of the promoter upstream region of the Blimp-1 gene (Prdm1) by forming a heterodimer with MafK. Bach2 and Bcl6 were found to interact with each other in B cells. While both Bach2 and Bcl6 possess the BTB domain which mediates protein-protein interactions, they interacted in a BTB-independent manner. Bcl6 is known to repress Prdm1 through a Bcl6 recognition element 1 in the intron 5, in which a putative, evolutionarily conserved MARE was identified. Both repressed the expression of a reporter gene containing the intron 5 region depending on the presence of the respective binding sites in 18-81 pre-B cells. Co-expression of Bach2 and Bcl6 resulted in further repression of the reporter plasmid. Chromatin immunoprecipitation assays showed MafK to bind to the intron MARE in various B cell lines, thus suggesting that it binds as a heterodimer with Bach2. Therefore, the interaction between Bach2 and Bcl6 might be crucial for the proper repression of Prdm1 in B cells.

A Research and Development Agenda for the National Institute of Education.

ERIC Educational Resources Information Center

Dupuis, Mary M., Ed.; And Others

This is one of several papers written to provide a rationale for programs of the new National Institute of Education (NIE). The basic elements of the rationale for each proposed NIE program and the sequence in which they will be discussed are: (1) educational goals to be achieved, (2) variables that can be manipulated to reach the goals, (3)…

Teacher Education and Curriculum for Development. Report of a Regional Planning Workshop (Quezon City, Philippines, May 19-31, 1975).

ERIC Educational Resources Information Center

Philippines Univ., Quezon City. Asian Inst. for Teacher Educators.

The Regional Planning Workshop on Teacher Education and Curriculum for Development had as its aim the preparation of guidelines for: 1) the development of modules for curriculum designers with reference to curriculum for development; 2) the development of modules for selected elements of the core curriculum of teacher education; and 3)…

Flipping the Classroom: An Effective Approach to Deal with Diversity at Higher Education

ERIC Educational Resources Information Center

Konijn, W. S.; Essink, D. R.; de Cock Buning, T.; Zweekhorst, M. B. M.

2018-01-01

Even though the flipped classroom is an increasingly popular method in education, a literature search shows a gap in research on this method in higher education. This article describes an experiment with two central questions: (1) How do students and lecturers assess the effectiveness of the FC method? And (2) What are crucial design elements? To…

Investigation of Hard Boron Rich Solids: Osmium Diboride and β-Rhombohedral Boron

NASA Astrophysics Data System (ADS)

Hebbache, M.; Živković, D.

Recently, we succeeded in synthesizing three osmium borides, i.e., OsB1.1, Os2B3 and OsB2. Up to date, almost nothing is known about the physical properties of these materials. Microhardness measurements show that OsB2 is extremely hard. Ab initio calculations show that it is due to formation of covalent bonds between boron atoms. OsB2 is also a low compressibility material. It can be used for hard coatings. The β-rhombohedral polymorph of boron is the second hardest elemental crystal (H ≈ 33 GPa). It is also very light and a p-type semiconductor. In early 1970s, it has been shown that the doping of boron with 3d transition elements enhances its hardness by about 25%. We predict that, in general, heavily doped samples MBx, with x ≤ 31 or equivalently a dopant concentration larger than 3.2 at.%, should be ultrahard, i.e., H > 43 GPa. The relevant dopants M are Al, Cu, Sc, Mn, Mg and Li. In addition to these properties, boron-rich materials have a very low volatility, a high chemical inertness and high melting point. They are suitable for applications under extreme conditions and thermoelectric equipment.

China’s Strategy Toward South and Central Asia: An Empty Fortress

DTIC Science & Technology

2014-01-01

Bookstore Make a charitable contribution Limited Electronic Distribution Rights This document and trademark( s ) contained herein are protected by...public service of the RAND Corporation. CHILDREN AND FAMILIES EDUCATION AND THE ARTS ENERGY AND ENVIRONMENT HEALTH AND HEALTH CARE INFRASTRUCTURE AND...An Empty Fortress 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT

MSIAC Journal. Volume 4, Issue 1, March 2009

DTIC Science & Technology

2009-03-01

CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ... PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR...education courses, publications, help desk, and projects . Contact the MSIAC at 888-566-7672 or at http://www.dod-msiac.org If you would like to submit

Educating Special Forces Junior Leaders for a Complex Security Environment

DTIC Science & Technology

2009-07-01

Security Environment 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK...UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) Joint Special Operations University,357 Tully Street Alison Building,Hurlburt Field,FL...32544 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM( S ) 11. SPONSOR

Assessment of G3(MP2)//B3 theory including a pseudopotential for molecules containing first-, second-, and third-row representative elements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rocha, Carlos Murilo Romero; Morgon, Nelson Henrique; Custodio, Rogério, E-mail: roger@iqm.unicamp.br

2013-11-14

G3(MP2)//B3 theory was modified to incorporate compact effective potential (CEP) pseudopotentials, providing a theoretical alternative referred to as G3(MP2)//B3-CEP for calculations involving first-, second-, and third-row representative elements. The G3/05 test set was used as a standard to evaluate the accuracy of the calculated properties. G3(MP2)//B3-CEP theory was applied to the study of 247 standard enthalpies of formation, 104 ionization energies, 63 electron affinities, 10 proton affinities, and 22 atomization energies, comprising 446 experimental energies. The mean absolute deviations compared with the experimental data for all thermochemical results presented an accuracy of 1.4 kcal mol{sup −1} for G3(MP2)//B3 and 1.6more » kcal mol{sup −1} for G3(MP2)//B3-CEP. Approximately 75% and 70% of the calculated properties are found with accuracy between ±2 kcal mol{sup −1} for G3(MP2)//B3 and G3(MP2)//B3-CEP, respectively. Considering a confidence interval of 95%, the results may oscillate between ±4.2 kcal mol{sup −1} and ±4.6 kcal mol{sup −1}, respectively. The overall statistical behavior indicates that the calculations using pseudopotential present similar behavior with the all-electron theory. Of equal importance to the accuracy is the CPU time, which was reduced by between 10% and 40%.« less

Junior High Environmental and Outdoor Education: Teacher

ERIC Educational Resources Information Center

Alberta Dept. of Education, Edmonton. Curriculum Branch.

This manual for Junior High Environmental and Outdoor Education courses specifically addresses the special needs of adolescent students. A program development model is organized around six elements: (1) outdoor core; (2) personal and group development; (3) environmental core; (4) outdoor expeditions; (5) environmental investigations; and (6)…

The Effects of Using Solar Radiation Pressure to Alleviate Fuel Requirements for Orbit Changing and Maintenance of the DSCS II F-13 Satellite

DTIC Science & Technology

2006-03-01

Owens J. “A Set of Modified Equinoctial Orbit Elements ,” Celestial Mechanics, 36 :409–419 (1985). 35. Wie B. Space Vehicle Dynamics and Control...14 MEE modified equinoctial elements . . . . . . . . . . . . . . . . . . . . . . . 14 TLE two-line element set ...satellite [32]. Vallado’s model will be incorporated into this thesis. 2.3.3 Modified Equinoctial Orbital Elements . For most astrodynamics problems, one of

Identifying educator behaviours for high quality verbal feedback in health professions education: literature review and expert refinement.

PubMed

Johnson, Christina E; Keating, Jennifer L; Boud, David J; Dalton, Megan; Kiegaldie, Debra; Hay, Margaret; McGrath, Barry; McKenzie, Wendy A; Nair, Kichu Balakrishnan R; Nestel, Debra; Palermo, Claire; Molloy, Elizabeth K

2016-03-22

Health professions education is characterised by work-based learning and relies on effective verbal feedback. However the literature reports problems in feedback practice, including lack of both learner engagement and explicit strategies for improving performance. It is not clear what constitutes high quality, learner-centred feedback or how educators can promote it. We hoped to enhance feedback in clinical practice by distinguishing the elements of an educator's role in feedback considered to influence learner outcomes, then develop descriptions of observable educator behaviours that exemplify them. An extensive literature review was conducted to identify i) information substantiating specific components of an educator's role in feedback asserted to have an important influence on learner outcomes and ii) verbal feedback instruments in health professions education, that may describe important educator activities in effective feedback. This information was used to construct a list of elements thought to be important in effective feedback. Based on these elements, descriptions of observable educator behaviours that represent effective feedback were developed and refined during three rounds of a Delphi process and a face-to-face meeting with experts across the health professions and education. The review identified more than 170 relevant articles (involving health professions, education, psychology and business literature) and ten verbal feedback instruments in health professions education (plus modified versions). Eighteen distinct elements of an educator's role in effective feedback were delineated. Twenty five descriptions of educator behaviours that align with the elements were ratified by the expert panel. This research clarifies the distinct elements of an educator's role in feedback considered to enhance learner outcomes. The corresponding set of observable educator behaviours aim to describe how an educator could engage, motivate and enable a learner to improve. This creates the foundation for developing a method to systematically evaluate the impact of verbal feedback on learner performance.

Trilateral Design and Test Code for Military Bridging and Gap-Crossing Equipment

DTIC Science & Technology

2005-05-01

Property data should be provided for individual lamina and for the ( laminat - ed) composite . The required lamina properties are identified in...Resistance Welding ....... a Brazing ......................... X Machining ..................... a Chemical Composition : Element... Machining .................. b Chemical Composition : Element % Si .................................. 0.2 max Fe

Regulation of the human ascorbate transporter SVCT2 exon 1b gene by zinc-finger transcription factors

PubMed Central

Qiao, Huan; May, James M.

2011-01-01

The sodium-dependent vitamin C transporter (SVCT) 2 is crucial for ascorbate uptake in metabolically active and specialized tissues. The present study focused on the gene regulation of the SVCT2 exon 1b, which is ubiquitously expressed in human and mouse tissues. Although the human SVCT2 exon 1b promoter doesn’t contain a classical TATA-box, we found that it does contain a functional initiator (Inr) that binds YY1 and interacts with upstream Sp1/Sp3 elements in the proximal promoter region. These elements in turn play a critical role in regulating YY1-mediated transcription of the exon 1b gene. Formation of YY1/Sp complexes on the promoter is required for its optional function. YY1 with Sp1 or Sp3 synergistically enhanced exon 1b promoter activity as well as the endogenous SVCT2 protein expression. Further, in addition to Sp1/Sp3 both EGR-1 and -2 were detected in the protein complexes that bound the three GC boxes bearing overlapping binding sites for EGR/WT1 and Sp1/3. The EGR family factors, WT1 and MAZ were found to differentially regulate exon 1b promoter activity. These results show that differential occupancy of transcription factors on the GC-rich consensus sequences in SVCT2 exon 1b promoter contributes to the regulation of cell and tissue expression of SVCT2. PMID:21335086

The effects of computer game elements in physics instruction software for middle schools: A study of cognitive and affective gains

NASA Astrophysics Data System (ADS)

Vasquez, David Alan

Can the educational effectiveness of physics instruction software for middle schoolers be improved by employing "game elements" commonly found in recreational computer games? This study utilized a selected set of game elements to contextualize and embellish physics word problems with the aim of making such problems more engaging. Game elements used included: (1) a fantasy-story context with developed characters; and (2) high-end graphics and visual effects. The primary purpose of the study was to find out if the added production cost of using such game elements was justified by proportionate gains in physics learning. The theoretical framework for the study was a modified version of Lepper and Malone's "intrinsically-motivating game elements" model. A key design issue in this model is the concept of "endogeneity", or the degree to which the game elements used in educational software are integrated with its learning content. Two competing courseware treatments were custom-designed and produced for the study; both dealt with Newton's first law. The first treatment (T1) was a 45 minute interactive tutorial that featured cartoon characters, color animations, hypertext, audio narration, and realistic motion simulations using the Interactive PhysicsspTM software. The second treatment (T2) was similar to the first except for the addition of approximately three minutes of cinema-like sequences where characters, game objectives, and a science-fiction story premise were described and portrayed with high-end graphics and visual effects. The sample of 47 middle school students was evenly divided between eighth and ninth graders and between boys and girls. Using a pretest/posttest experimental design, the independent variables for the study were: (1) two levels of treatment; (2) gender; and (3) two schools. The dependent variables were scores on a written posttest for both: (1) physics learning, and (2) attitude toward physics learning. Findings indicated that, although substantial physics learning took place within both treatments (learning-gain effect sizes exceeded 1.5 sigma), there were no statistically significant differences between the two treatments. The primary conclusion drawn from this finding was that the ratio of "story" to physics-learning content (3 minutes/45 minutes) in T2 was too small to make an educational difference and should be experimentally increased.

Call to claim your prize: Perceived benefits and risk drive intention to comply in a mass marketing scam.

PubMed

Wood, Stacey; Liu, Pi-Ju; Hanoch, Yaniv; Xi, Patricia M; Klapatch, Lukas

2018-06-01

Mass marketing scams extract an enormous toll, yet the literature on scams is just emerging. In Experiment 1, 211 adults reviewed a solicitation and rated their intention of contacting an "activation number" for a prize. Scarcity and authority were manipulated. Many (48.82%) indicated some willingness to contact to "activate" the winnings. Intention of responding was inversely related to the perception of risk (b = -.441, p < .001) and positively associated with perception of benefits (b = .554, p < .001), but not with the experimental condition. In Experiment 2, 291 adults were randomly assigned to one of the three conditions (low, medium, or high activation fee), and were asked to report willingness to contact. Activation fees decreased intent to contact, but percentages remained high (25.70%), with higher perception of risk reducing contact rates (b = -.581, p < .001), and benefit perception increasing intent to contact (b = .381, p < .001). Our studies indicate that consumers are responding to perceived risks and benefits in their decision-making, regardless of persuasion elements used by scammers. In summary, our studies find that consumers with lower levels of education and high perception of benefits are at increased risk for mass marketing scams. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Beam Generated Vorticity and Convective Channel Mixing.

DTIC Science & Technology

1980-09-17

one . PERFORMING ORGANIZATION NAME AND ADDRESS ,0. PROGRAM ELEMENT. PROJECT. TASK Laboratory for Computational Physics Naval Research Laboratory.- 62...profile, Eq. (21). Letting the integration variable be q- riR. yields If d’n. g(SO[71b + ci) V(r) - U 2 1 a dq (1 + 7 -a2 )2 fd 77 g ( Soic -7b)- g

45 CFR Appendix B to Part 1355 - Adoption Data Elements

Code of Federal Regulations, 2011 CFR

2011-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON CHILDREN, YOUTH AND FAMILIES, FOSTER CARE MAINTENANCE PAYMENTS, ADOPTION ASSISTANCE, AND CHILD AND FAMILY SERVICES GENERAL Pt. 1355, App. B Appendix B... in This Adoption? ____ Yes: 1 No: 2 II. Child's Demographic Information A. Date of Birth __(mo...

45 CFR Appendix B to Part 1355 - Adoption Data Elements

Code of Federal Regulations, 2012 CFR

2012-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON CHILDREN, YOUTH AND FAMILIES, FOSTER CARE MAINTENANCE PAYMENTS, ADOPTION ASSISTANCE, AND CHILD AND FAMILY SERVICES GENERAL Pt. 1355, App. B Appendix B... Have any Involvement in This Adoption? __ Yes: 1 No: 2 II. Child's Demographic Information A. Date of...

45 CFR Appendix B to Part 1355 - Adoption Data Elements

Code of Federal Regulations, 2010 CFR

2010-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON CHILDREN, YOUTH AND FAMILIES, FOSTER CARE MAINTENANCE PAYMENTS, ADOPTION ASSISTANCE, AND CHILD AND FAMILY SERVICES GENERAL Pt. 1355, App. B Appendix B... in This Adoption? ____ Yes: 1 No: 2 II. Child's Demographic Information A. Date of Birth __(mo...

45 CFR Appendix B to Part 1355 - Adoption Data Elements

Code of Federal Regulations, 2013 CFR

2013-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON CHILDREN, YOUTH AND FAMILIES, FOSTER CARE MAINTENANCE PAYMENTS, ADOPTION ASSISTANCE, AND CHILD AND FAMILY SERVICES GENERAL Pt. 1355, App. B Appendix B... Have any Involvement in This Adoption? __ Yes: 1 No: 2 II. Child's Demographic Information A. Date of...

45 CFR Appendix B to Part 1355 - Adoption Data Elements

Code of Federal Regulations, 2014 CFR

2014-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON CHILDREN, YOUTH AND FAMILIES, FOSTER CARE MAINTENANCE PAYMENTS, ADOPTION ASSISTANCE, AND CHILD AND FAMILY SERVICES GENERAL Pt. 1355, App. B Appendix B... Have any Involvement in This Adoption? __ Yes: 1 No: 2 II. Child's Demographic Information A. Date of...

Hybrid Finite Element Analysis of Free Edge Effect in Symmetric Composite Laminates

DTIC Science & Technology

1983-06-01

SJ3 (i,j = 1,2,4,5,6) (A.1.7)i Sij - S3 3 For symmetric angle ply case 814 : B24 = B34 = B54 : 0 (A.1.8)I B16 B 2 6 =B 3 6 =B 6 =0 In matrix form, eq...A.1.6) can be written as c = B a + co (A.l.9) 36 wi th c Xx c yy yz (A.1.10) zx c xy B 1 . B16 B = 5 x 5 matrix (A . I) B61 B6 6 axx yy (A..12...3.38) u rc+l 6 Ca+l *wU +l E: Aku rk (Ck)k=l where u 2 Pk = B 1 u ( uku) + B2 u - Bl6 Uuk u+xku(Bl5u k uB14 U) uB u qu= B u u + B22 - B26 + ku (B25U

Measuring H, O, li, B, and BE on Planetary Surfaces: Calibration of Laser-Induced Breakdown Spectroscopy (libs) Data Under Air, Vacuum, and CO2

NASA Astrophysics Data System (ADS)

Dyar, M. D.; Nelms, M.; Breves, E. A.

2012-12-01

Laser-induced breakdown spectrometer (LIBS), as implemented on the ChemCam instrument on Mars Science Lab and the proposed New Frontiers SAGE mission to Venus, can analyze elements from H to Pb from up to 7m standoff. This study examines the capabilities of LIBS to analyze H, O, B, Be, and Li under conditions simulating Earth, the Moon, and Mars. Of these, H is a major constituent of clay minerals and a key indicator of the presence of water. Its abundance in terrestrial materials ranges from 0 ppm up to 10's of wt.% H2O in hydrated sulfates and clays, with prominent emission lines occurring ca. 656.4 nm. O is an important indicator of atmospheric and magmatic coevolution, and has lines ca. 615.8, 656.2, 777.6, and 844.8 nm. Unfortunately there are very few geological samples from which O has been directly measured, but stoichiometry suggests that O varies from ca. 0 wt.% in sulfides to 21% in ferberite, 32% in ilmenite, 42% in amphiboles, 53% in quartz, 63% in melanterite, and 71% in epsomite. Li (lines at 413.3, 460.4, and 670.9 nm in vacuum), B (412.3 nm), and Be (313.1 nm) are highly mobile elements and key indicators of interaction with water. Local atmospheric composition and pressure significantly influence LIBS plasma intensity because the local atmosphere and the breakdown products from the atmospheric species interact with the ablated surface material in the plasma. Measurement of light elements with LIBS requires that spectra be acquired under conditions matching the remote environment. LIBS is critically dependent on the availability of well characterized, homogeneous reference materials that are closely matched in matrix (composition and structure) to the sample being studied. In modern geochemistry, analyses of most major, minor, and trace elements are routinely made. However, quantitative determination of light element concentrations in geological specimens still represents a major analytical challenge. Thus standards for which hydrogen, oxygen, and other light elements are directly measured are nearly nonexistent in the 1-2 g quantities needed for LIBS analyses. For this study, we have obtained two sample suites that provide calibrations needed for accurate analyses of H, O, B, Be, and Li in geological samples. The first suite of 11 samples was analyzed for oxygen by fast neutron activation analysis. The second suite includes 11 gem-quality minerals representing the major rock-forming species for B, Li, and Be-rich parageneses. Light elements were directly analyzed using a combination of EMPA, XRF, ion microprobe, uranium extraction, proton-induced gamma-ray emission (PIGE), and prompt gamma-ray neutron activation analysis (PGNAA). LIBS spectra were acquired at Mount Holyoke College under air, vacuum, and CO2 to simulate terrestrial, lunar, and martian environments. Spectra were then used to develop three separate calibration models (one for each environment), enabling LIBS characterization of light elements using multivariate analyses. Results show that when direct analyses of H, O, Li, B, and Be are used rather than LOI results, inferred, or indirectly calculated values, optimal root mean squared errors of prediction result. We are actively adding samples to these calibration suites, and we expect that prediction errors (accuracies) of <1wt% for these elements are possible.

Magnetic properties enhancement of melt spun CoZrB ribbons by elemental substitutions

NASA Astrophysics Data System (ADS)

Chang, H. W.; Tsai, C. F.; Hsieh, C. C.; Shih, C. W.; Chang, W. C.; Shaw, C. C.

2013-11-01

Effect of elemental substitution of M (M=C, Cu, Ga, Al and Si) for Zr on the magnetic properties, phase evolution, and microstructure of melt spun Co80Zr18-xMxB2 (x=0-2) ribbons have been investigated. The x-ray diffraction (XRD) and thermal magnetic analysis (TMA) results showed that two magnetically soft phases, namely fcc-Co and Co23Zr6, coexisted with hard phase Co5Zr in Co80Zr17M1B2 ribbons with M=Cu, Ga, Al and Si, while an extra unknown magnetic phase was present in ribbons with M=C. The ribbons with M=C and Si were found to improve the remanence (σr) of the Co80Zr17M1B2 ribbons. However, only M=Si could improve the whole magnetic properties, including Br, intrinsic coercivity (iHc) and energy product ((BH)max) of the above ribbons. The optimal magnetic properties of Br=5.2 kG, iHc=4.5 kOe, and (BH)max=5.3 MGOe were obtained in Co80Zr17Si1B2 ribbons, which possessed Co5Zr and minor fcc-Co phases with much finer grain size (10-30 nm) in comparison with its counterpart Co80Zr18B2 (20-60 nm).

Large Eddy Simulations of Transverse Combustion Instability in a Multi-Element Injector

DTIC Science & Technology

2016-07-27

Instability in a Multi- Element Injector 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Matthew Harvazinski, Yogin...Simulations of Transverse  Combustion Instability in a Multi‐ Element  Injector 2 History Damaged engine injector  faceplate caused by combustion...Clearance #16346 3 Single  Element  Studies Short Post Marginally Stable Intermediate Post Unstable Long Post Stable Long Post Unstable CVRC Experiment

Improving the theoretical prediction for the Bs - B̅s width difference: matrix elements of next-to-leading order ΔB = 2 operators

NASA Astrophysics Data System (ADS)

Davies, Christine; Harrison, Judd; Lepage, G. Peter; Monahan, Christopher; Shigemitsu, Junko; Wingate, Matthew

2018-03-01

We present lattice QCD results for the matrix elements of R2 and other dimension-7, ΔB = 2 operators relevant for calculations of Δs, the Bs - B̅s width difference. We have computed correlation functions using 5 ensembles of the MILC Collaboration's 2+1 + 1-flavour gauge field configurations, spanning 3 lattice spacings and light sea quarks masses down to the physical point. The HISQ action is used for the valence strange quarks, and the NRQCD action is used for the bottom quarks. Once our analysis is complete, the theoretical uncertainty in the Standard Model prediction for ΔΓs will be substantially reduced.

Material flow analysis of NdFeB magnets for Denmark: a comprehensive waste flow sampling and analysis approach.

PubMed

Habib, Komal; Schibye, Peter Klausen; Vestbø, Andreas Peter; Dall, Ole; Wenzel, Henrik

2014-10-21

Neodymium-iron-boron (NdFeB) magnets have become highly desirable for modern hi-tech applications. These magnets, in general, contain two key rare earth elements (REEs), i.e., neodymium (Nd) and dysprosium (Dy), which are responsible for the very high strength of these magnets, allowing for considerable size and weight reduction in modern applications. This study aims to explore the current and future potential of a secondary supply of neodymium and dysprosium from recycling of NdFeB magnets. For this purpose, material flow analysis (MFA) has been carried out to perform the detailed mapping of stocks and flows of NdFeB magnets in Denmark. A novel element of this study is the value added to the traditionally practiced MFAs at national and/or global levels by complementing them with a comprehensive sampling and elemental analysis of NdFeB magnets, taken out from a sample of 157 different products representing 18 various product types. The results show that the current amount of neodymium and dysprosium in NdFeB magnets present in the Danish waste stream is only 3 and 0.2 Mg, respectively. However, this number is estimated to increase to 175 Mg of neodymium and 11.4 Mg of dysprosium by 2035. Nevertheless, efficient recovery of these elements from a very diverse electronic waste stream remains a logistic and economic challenge.

Performance Based Teacher Education. What is the State of the Art?

ERIC Educational Resources Information Center

Elam, Stanley

This document clarifies the concepts of Performance Based Teacher Education, examines their potential, and identifies problems and questions. Five essential elements are identified: 1) teaching competencies to be demonstrated are role-derived, specified in behavioral terms, and made public; 2) assessment criteria are competency-based, specify…

Citizen Organizations: Citizen Participation in Educational Decisionmaking. Executive Summary.

ERIC Educational Resources Information Center

Gittell, Marilyn; And Others

In order to examine the role and effectiveness of community organizations in increasing parental and community involvement in educational decision making, a research project was initiated which included three elements: (1) case studies documenting the behavior of organizations and internal and external factors that influence their functioning, (2)…

Vocational Education Administration Handbook. Edition #2.

ERIC Educational Resources Information Center

Cropley, Russell, Ed.; Doherty, Susan Sloan, Ed.

This handbook clarifies the elements of a vocational education program and provides direction to help the administrators of Alaska's vocational programs to plan and implement high quality programs. The handbook provides information on the regulations and standards for vocational programs. The handbook is organized in three parts. Part 1 provides…

Quantitative mapping of elemental distribution in leaves of the metallophytes Helichrysum candolleanum, Blepharis aspera, and Blepharis diversispina from Selkirk Cu-Ni mine, Botswana

NASA Astrophysics Data System (ADS)

Koosaletse-Mswela, Pulane; Przybyłowicz, Wojciech J.; Cloete, Karen J.; Barnabas, Alban D.; Torto, Nelson; Mesjasz-Przybyłowicz, Jolanta

2015-11-01

Multi-element profiling is essential in understanding the metal-tolerant behavior of metallophytes. Although previous reports using multi-elemental analyses show that the metallophytes Blepharis aspera, Blepharis diversispina (Acanthaceae) and Helichrysum candolleanum (Asteraceae) take up metals, no information exists on elemental spatial distribution and concentrations in specific tissues of these plants. The aim of this study therefore was to assess the spatial distribution and concentration of copper, nickel and other elements in leaf tissues of these plants using micro-PIXE. Whole plants were collected with soil in pots from an operational copper and nickel mine (i.e., a copper and nickel mineralized area), Selkirk, about 40 km north-east of Francistown, Botswana. On the same day the samples were transported by air to iThemba LABS in South Africa. Leaf specimens were cryofixed in liquid propane cooled by LN2. Parallel samples were embedded in resin for anatomical studies to facilitate interpretation of elemental maps. The distribution and concentration of copper, nickel, and other elements in leaf tissues were determined using micro-PIXE and proton backscattering spectrometry. Data evaluation was performed using GeoPIXE II software. Micro-PIXE showed that H. candolleanum had the highest whole leaf content of copper (70 ± 3 μg g-1 DW) and nickel (168 ± 5 μg g-1 DW), followed by B. aspera (Cu: 25 ± 1 μg g-1 DW; Ni: 166 ± 4 μg g-1 DW) and B. diversispina (Cu: 3 ± 1 μg g-1 DW; Ni, below detection limit). For specific leaf tissues, the highest levels of copper were found in the vascular bundle for H. candolleanum (167 ± 7 μg g-1 DW) and the lower epidermis for B. aspera (70 ± 9 μg g-1 DW). The highest levels of nickel were present in the vascular bundle of B. aspera (479 ± 10 μg g-1 DW) and H. candolleanum (90 ± 5 μg g-1 DW). Elemental maps showed a similar distribution pattern for copper and nickel in B. aspera and B diversispina, with these elements concentrated in the upper and lower epidermal regions. However, for H. candolleanum, both copper and nickel were concentrated in the mesophyll. The difference in concentration and accumulation patterns between B. aspera, B. diversispina and H. candolleanum suggests that the metal-tolerant adaptation of these metallophytes may differ.

Performance of a four-element Ka-band high-temperature superconducting microstrip antenna

NASA Technical Reports Server (NTRS)

Richard, M. A.; Bhasin, K. B.; Gilbert, C.; Metzler, S.; Koepf, G.; Claspy, P. C.

1992-01-01

Superconducting four-element microstrip array antennas operating at 30 GHz have been designed and fabricated on a lanthanum aluminate (LaAlO3) substrates. The experimental performance of these thin film Y-Ba-Cu-O superconducting antennas is compared with that of identical antenna patterned with evaporated gold. Efficiency measurements of these antennas show an improvement of 2 dB at 70 K and as much as 3.5 dB at 40 K in the superconducting antenna over the gold antenna.

Analysis of elemental concentration using ICP-AES and pathogen indicator in drinking water of Qasim Abad, District Rawalpindi, Pakistan.

PubMed

Sehar, Shama; Naz, Iffat; Ali, Naeem; Ahmed, Safia

2013-02-01

The present study was conducted to investigate drinking water quality (groundwater) from water samples taken from Qasim Abad, a locality of approximately 5,000 population, situated between twin cities Rawalpindi and Islamabad in Pakistan. The main sources of drinking water in this area are water bores which are dug upto the depth of 250-280 ft in almost every house. The study consists of the determination of physico-chemical properties, trace metals, heavy metals, rare earth elements and microbiological quality of drinking water. The data showed the variation of the investigated parameters in samples as follows: pH 6.75 to 8.70, electrical conductivity 540 to 855 μS/cm, total dissolved solids 325.46 to 515.23 ppm and dissolved oxygen 1.50 to 5.64 mg/L which are within the WHO guidelines for drinking water quality. The water samples were analysed for 30 elements (aluminium, iron, magnesium, manganese, silicon, zinc, molybdenum, titanium, chromium, nickel, tungsten, silver, arsenic, boron, barium, beryllium, cadmium, cobalt, copper, gallium, mercury, lanthanum, niobium, neodymium, lead, selenium, samarium, tin, vanadium and zirconium) by using inductively coupled plasma atomic emission spectroscopy. The organic contamination was detected in terms of most probable number (MPN) of faecal coliforms. Overall, elemental levels were lower than the recommended values but three water bores (B-1, B-6, B-7) had higher values of iron (1.6, 2.206, 0.65 ppm), two water bores (B-1, B-6) had higher values of aluminium (0.95, 1.92 ppm), respectively, and molybdenum was higher by 0.01 ppm only in one water bore (B-11). The total number of coliforms present in water samples was found to be within the prescribed limit of the WHO except for 5 out of 11 bore water samples (B-2, B-3, B-4, B-8, B-11), which were found in the range 5-35 MPN/100 mL, a consequence of infiltration of contaminated water (sewage) through cross connection, leakage points and back siphoning.

Molecular genetic mechanisms of allelic specific regulation of murine Comt expression

PubMed Central

Segall, Samantha K.; Shabalina, Svetlana A.; Meloto, Carolina B.; Wen, Xia; Cunningham, Danielle; Tarantino, Lisa M.; Wiltshire, Tim; Gauthier, Josée; Tohyama, Sarasa; Martin, Loren J.; Mogil, Jeffrey S.; Diatchenko, Luda

2015-01-01

Abstract A functional allele of the mouse catechol-O-methyltransferase (Comt) gene is defined by the insertion of a B2 short interspersed repeat element in its 3′-untranslated region (UTR). This allele has been associated with a number of phenotypes, such as pain and anxiety. In comparison with mice carrying the ancestral allele (Comt+), ComtB2i mice show higher Comt mRNA and enzymatic activity levels. Here, we investigated the molecular genetic mechanisms underlying this allelic specific regulation of Comt expression. Insertion of the B2 element introduces an early polyadenylation signal generating a shorter Comt transcript, in addition to the longer ancestral mRNA. Comparative analysis and in silico prediction of Comt mRNA potential targets within the transcript 3′ to the B2 element was performed and allowed choosing microRNA (miRNA) candidates for experimental screening: mmu-miR-3470a, mmu-miR-3470b, and mmu-miR-667. Cell transfection with each miRNA downregulated the expression of the ancestral transcript and COMT enzymatic activity. Our in vivo experiments showed that mmu-miR-667-3p is strongly correlated with decreasing amounts of Comt mRNA in the brain, and lentiviral injections of mmu-miR-3470a, mmu-miR-3470b, and mmu-miR-667 increase hypersensitivity in the mouse formalin model, consistent with reduced COMT activity. In summary, our data demonstrate that the Comt+ transcript contains regulatory miRNA signals in its 3′-untranslated region leading to mRNA degradation; these signals, however, are absent in the shorter transcript, resulting in higher mRNA expression and activity levels. PMID:26067582

[Finite element analysis of the maxillary central incisor with crown lengthening surgery and post-core restoration in management of crown-root fracture].

PubMed

Zhen, Min; Hu, Wen-jie; Rong, Qi-guo

2015-12-18

To construct the finite element models of maxillary central incisor and the simulations with crown lengthening surgery and post-core restoration in management of different crown-root fracture types, to investigate the stress intensity and distributions of these models mentioned above, and to analyze the indications of crown lengthening from the point of view of mechanics. An extracted maxillary central incisor and alveolar bone plaster model were scanned by Micro-CT and dental impression scanner (3shape D700) respectively. Then the 3D finite element models of the maxillary central incisor and 9 simulations with crown lengthening surgery and post-core restoration were constructed by Mimics 10.0, Geomagic studio 9.0 and ANSYS 14.0 software. The oblique static force (100 N) was applied to the palatal surface (the junctional area of the incisal 1/3 and middle 1/3), at 45 degrees to the longitudinal axis, then the von Mises stress of dentin, periodontal ligament, alveolar bone, post and core, as well as the periodontal ligament area, were calculated. A total of 10 high-precision three-dimensional finite element models of maxillary central incisor were established. The von Mises stress of models: post>dentin>alveolar bone>core>periodontal ligament, and the von Mises stress increased linearly with the augmentation of fracture degree (besides the core). The periodontal ligament area of the crown lengthening was reduced by 12% to 33%. The von Mises stress of periodontal ligament of the B2L2c, B2L3c, B3L1c, B3L2c, B3L3c models exceeded their threshold limit value, respectively. The maxillary central incisors with the labial fracture greater than three-quarter crown length and the palatal fracture deeper than 1 mm below the alveolar crest are not the ideal indications of the crown lengthening surgery.

Conditions of Mytilus edulis extracellular body fluids and shell composition in a pH-treatment experiment: Acid-base status, trace elements and δ11B

NASA Astrophysics Data System (ADS)

Heinemann, Agnes; Fietzke, Jan; Melzner, Frank; BöHm, Florian; Thomsen, JöRn; Garbe-SchöNberg, Dieter; Eisenhauer, Anton

2012-01-01

Mytilus edulis were cultured for 3 months under six different seawater pCO2 levels ranging from 380 to 4000 μatm. Specimen were taken from Kiel Fjord (Western Baltic Sea, Germany) which is a habitat with high and variable seawater pCO2 and related shifts in carbonate system speciation (e.g., low pH and low CaCO3 saturation state). Hemolymph (HL) and extrapallial fluid (EPF) samples were analyzed for pH and total dissolved inorganic carbon (CT) to calculate pCO2 and [HCO3-]. A second experiment was conducted for 2 months with three different pCO2 levels (380, 1400 and 4000 μatm). Boron isotopes (δ11B) were investigated by LA-MC-ICP-MS (Laser Ablation-Multicollector-Inductively Coupled Plasma-Mass Spectrometry) in shell portions precipitated during experimental treatment time. Additionally, elemental ratios (B/Ca, Mg/Ca and Sr/Ca) in the EPF of specimen from the second experiment were measured via ICP-OES (Inductively Coupled Plasma-Optical Emission Spectrometry). Extracellular pH was not significantly different in HL and EPF but systematically lower than ambient water pH. This is due to high extracellular pCO2 values, a prerequisite for metabolic CO2 excretion. No accumulation of extracellular [HCO3-] was measured. Elemental ratios (B/Ca, Mg/Ca and Sr/Ca) in the EPF increased slightly with pH which is in accordance with increasing growth and calcification rates at higher seawater pH values. Boron isotope ratios were highly variable between different individuals but also within single shells. This corresponds to a high individual variability in fluid B/Ca ratios and may be due to high boron concentrations in the organic parts of the shell. The mean δ11B value shows no trend with pH but appears to represent internal pH (EPF) rather than ambient water pH.

Physical and chemical properties of biochars co-composted with biowastes and incubated with a chicken litter compost.

PubMed

Khan, Naser; Clark, Ian; Sánchez-Monedero, Miguel A; Shea, Syd; Meier, Sebastian; Qi, Fangjie; Kookana, Rai S; Bolan, Nanthi

2016-01-01

Two experiments were conducted where three biochars, made from macadamia nutshell (MS), hardwood shaving (WS) and chicken litter (CL), were co-composted with chicken manure and sawdust, and also incubated with a chicken litter based commercial compost. Biochars were added at the rates of 5% and 10% in the co-composting and 10% and 20% in the incubation experiment. The rates of biochar had no consistent effect on the change in element contents of composted- or incubated-biochars. The biochar C demonstrated recalcitrance in both composting and incubation systems. Composting increased the CEC of biochars probably due to thermophilic oxidation. The increases in CEC of WS and CL were 6.5 and 2.2 times, respectively, for composting. Translocation of elements, between biochar and compost medium, occurred in both directions. In most cases, biochars gained elements under the influence of positive difference of concentrations (i.e., when compost medium had higher concentration of elements than biochar), while in some cases they lost elements despite a positive difference. Biochar lost some elements (WS: B; CL: B, Mg and S) under the influence of negative difference of concentrations. Some biochars showed strong affinity for B, C, N and S: the concentration of these elements gained by biochars surpassed the concentration in the respective composting medium. The material difference in the biochars did not have influence on N retention: all three netbag-biochars increased their N content. The cost of production of biochar-compost will be lower in co-composting than incubation, which involves two separate processes, i.e., composting and subsequent incubation. Copyright © 2015 Elsevier Ltd. All rights reserved.

Activation of IFN-beta element by IRF-1 requires a posttranslational event in addition to IRF-1 synthesis.

PubMed Central

Watanabe, N; Sakakibara, J; Hovanessian, A G; Taniguchi, T; Fujita, T

1991-01-01

Expression of the Type I IFN (i.e., IFN-alpha s and IFN-beta) genes is efficiently induced by viruses at the transcriptional level. This induction is mediated by at least two types of positive regulatory elements located in the human IFN-beta gene promoter: (1) the repeated elements which bind both the transcriptional activator IRF-1 and the repressor IRF-2 (IRF-elements; IRF-Es), and (2) the kappa B element (kappa B-E), which binds NF kappa B and is located between the IRF-Es and the TATA box. In this study we demonstrate that a promoter containing synthetic IRF-E, which displays high affinity for the IRFs can be efficiently activated by Newcastle disease virus (NDV). In contrast, such activation was either very weak or nil when cells were treated by IFN-beta or tumor necrosis factor-alpha (TNF-alpha), despite the fact they both efficiently induce de novo synthesis of the short-lived IRF-1 in L929 cells. In fact, efficient activation of the IRF-E apparently requires an event in addition to de novo IRF-1 induction, which can be elicited by NDV even in the presence of protein synthesis inhibitor, cycloheximide. Moreover, efficient activation of the IRF-E by NDV is specifically inhibited by the protein kinase inhibitor, Staurosporin. Hence our results suggest the importance of IRF-1 synthesis and post-translational modification event(s), possibly phosphorylation for the efficient activation of IRF-Es, which are otherwise under negative regulation by IRF-2. Images PMID:1886766

78 FR 54242 - 36(b)(1) Arms Sales Notification

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-03

... elements of logistical and program support. The estimated cost is $1.2 billion. This proposed sale will... support services, and other related elements of logistical and program support. (iv) Military Department... logistical support to sustain the combat and operational readiness of its existing aircraft fleet. The...

Technology Options for Multimedia in Distance Learning. A Report for the Commission of the European Communities--Task Force Human Resources, Education, Training, and Youth.

ERIC Educational Resources Information Center

Sherwood-Roberts, P.; Vervest, P.

This report focuses on interactive multimedia delivery platforms available for distance education. An introduction addresses the role of distance education and open learning in covering training needs and advantages of interactive multimedia in training. Chapter 2 proposes a multimedia skills evaluation framework and examines the elements of this…

The Systematics of Light Lithophile Elements (Li, Be, B) in Lunar Picritic Glasses

NASA Astrophysics Data System (ADS)

Shearer, C. K.; Layne, G. D.; Papike, J. J.

1993-07-01

Lunar picritic glasses are thought to be the product of either partial melting of the deep lunar mantle followed by rapid ascent [1,2] or polybaric partial melting initiated in the deep lunar mantle [3]. The near primary compositions of these volcanic glasses provide us with a unique perspective for evaluating mare basaltic magmatism and the characteristics and evolution of the lunar mantle. Because of their obvious importance in deciphering the evolution of the Earth-Moon system, we have initiated an extensive trace element study of these picritic glasses using ion microprobe techniques. Here, we report the initial results of light lithophile element (LLE) analyses of these glasses. This is the first reported study of LLE in lunar basalts. The LLE have only recently received attention in terrestrial basaltic systems [4-6]. Their correlations with other more routinely analyzed trace elements (Li:Yb or V, Be:Nd, B:K) in a variety of terrestrial mantle environments have yielded several important insights into mantle magmatism [4-6]. Ion microprobe analyses of the glasses were conducted using a Cameca 4f ion microprobe operated on the UNM campus. The light lithophile elements were analyzed under the following conditions: 10-kV O- primary beam, 8-nA primary beam current, 10-15-micrometer beam diameter, sample voltage offset of -70 +- 25 V, and a 150-micrometer secondary ion image field with a 33-micrometer field aperature inserted. Counting times included background (2 seconds), 30Si (2 seconds), 7Li (2 seconds), 9Be (4 seconds), and 11B (8 seconds). Each analysis involved 30 to 40 counting cycles. These counting times resulted in precision for Li of better than 1.2% and for B and Be of better than 2.2%. Standards for Li, Be, and B in basaltic glass matrices were kindly provided by J. Ryan [4-6]. Calibration curves (LLE/30Si x wt% SiO2 vs. LLE concentration) were originally defined by a minimum of five standards for each element and are linear for the concentration ranges found in the picritic lunar glasses. Picritic glasses analyzed in the initial study were from the Apollo 12, 14, 15, and 17 sites. This suite of glasses ranged in TiO2 from 0.3 to 17 wt%. All glasses had been previously analyzed for major and trace elements (REE, Cr, V, Sr, Ba, Co, Zr) by electron microprobe and ion microprobe [2]. The LLE show a wide range of variability with Li ranging from 1.2 to 23.8 ppm, Be ranging from 0.06 to 3.09 ppm, and B ranging from 0.20 to 3.87 ppm. Traverses across individual glass beads suggest they are homogeneous with regard to LLE. Except for the A17 VLT glasses and the A15 yellow glasses, the individual glass groups [1] show very limited LLE variability. LLE content is positively correlated to TiO2 content. LLE concentrations also parallel the enrichment of other lithophile elements such as Ba, Zr, Sr, and the REE. Unlike terrestrial basalts [4-6], the concentration of LLE in the picritic glasses is negatively correlated with SiO2 and MgO. B/Be ranges from 0.40 to 4.6. Over 85% of the analyzed glasses have B/Be between 0.9 and 3.0, similar to the average B/Be value of 3 for MORB [6]. Li/B and Li/Be values range from 3.2 to 30.8 and 2.7 to 41.7, respectively. These LLE ratios are not correlated with TiO2, but appear to be characteristic of individual sampling sites and therefore reflect subtle differences in the sources of the picritic magmas. The LLE and LLE ratios also indicate a KREEP component had been incorporated into some of these picritic magmas. Shearer and Papike [2] suggested this incorporation occurs in the zone of melting and reflected overturning of the LMO cumulate pile. The initial data reported here suggest that the LLE may be useful in deciphering the mare basalt record. Further analyses of these glasses will allow a more detailed comparison of picritic glass sources with mare basalt sources and a better interpretation of the compositional relationships among picritic glasses. Acknowledgments: SIMS analyses were performed at the UNM/SNL Ion Microprobe Facility, a joint operation of the Institute of Meteoritics, UNM, and Sandia National Laboratories. This research was funded by NASA grant NAGW-3347. References: [1] Delano J. W. (1986) Proc. LPSC, 16th, in JGR, XX D201-D213. [2] Shearer C. K. and Papike J. J. (1993) GCA, in review. [3] Longhi J. (1992) GCA, 56, 2235-2252. [4] Ryan J. G. and Langmuir C. H. (1987) GCA, 51, 1727- 1741. [5] Ryan J. G. and Langmuir C. H. (1988) GCA, 52, 237-244. [6] Ryan J. G. and Langmuir C. H. (1993) GCA, 57, 1489-1498.

Co-regulation of nuclear respiratory factor-1 by NFκB and CREB links LPS-induced inflammation to mitochondrial biogenesis

PubMed Central

Suliman, Hagir B.; Sweeney, Timothy E.; Withers, Crystal M.; Piantadosi, Claude A.

2010-01-01

The nuclear respiratory factor-1 (NRF1) gene is activated by lipopolysaccharide (LPS), which might reflect TLR4-mediated mitigation of cellular inflammatory damage via initiation of mitochondrial biogenesis. To test this hypothesis, we examined NRF1 promoter regulation by NFκB, and identified interspecies-conserved κB-responsive promoter and intronic elements in the NRF1 locus. In mice, activation of Nrf1 and its downstream target, Tfam, by Escherichia coli was contingent on NFκB, and in LPS-treated hepatocytes, NFκB served as an NRF1 enhancer element in conjunction with NFκB promoter binding. Unexpectedly, optimal NRF1 promoter activity after LPS also required binding by the energy-state-dependent transcription factor CREB. EMSA and ChIP assays confirmed p65 and CREB binding to the NRF1 promoter and p65 binding to intron 1. Functionality for both transcription factors was validated by gene-knockdown studies. LPS regulation of NRF1 led to mtDNA-encoded gene expression and expansion of mtDNA copy number. In cells expressing plasmid constructs containing the NRF-1 promoter and GFP, LPS-dependent reporter activity was abolished by cis-acting κB-element mutations, and nuclear accumulation of NFκB and CREB demonstrated dependence on mitochondrial H2O2. These findings indicate that TLR4-dependent NFκB and CREB activation co-regulate the NRF1 promoter with NFκB intronic enhancement and redox-regulated nuclear translocation, leading to downstream target-gene expression, and identify NRF-1 as an early-phase component of the host antibacterial defenses. PMID:20587593

Functional analysis of the OCA-B promoter.

PubMed

Stevens, S; Wang, L; Roeder, R G

2000-06-15

OCA-B was identified as a B cell-specific coactivator that functions with either Oct-1 or Oct-2 to mediate efficient cell type-specific transcription via the octamer site (ATGCAAAT) both in vivo and in vitro. Mice lacking OCA-B exhibit normal Ag-independent B cell maturation. In contrast, Ag-dependent functions, including production of secondary Ig isotypes and germinal center formation, are greatly affected. To better understand OCA-B expression and, ultimately, the defects observed in the OCA-B knockout mice, we have cloned the OCA-B promoter and examined its function in both transformed and primary B cells. We show here that the OCA-B promoter is developmentally regulated, with activity increasing throughout B cell differentiation. Through physical and functional assays, we have found an activating transcription factor/cAMP response element binding protein binding site (or cAMP response element) that is crucial for OCA-B promoter activity. Furthermore, we demonstrate that IL-4 and anti-CD40 induce both the OCA-B promoter and octamer-dependent promoters, thus implicating OCA-B in B cell signaling events in the nucleus.

Equal Educational Opportunity: Hearings Before the Select Committee on Equal Educational Opportunity of the United States Senate, Ninety-First Congress, Second Session on Equal Educational Opportunity. Parts 1A, 1B, 2, 3A, 3B, 3C, and 3D.

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. Senate Select Committee on Equal Educational Opportunity.

These hearings before the Senate Select Committee on Equal Educational Opportunity are organized in three parts, the contents of which are as follows: Part 1A and Part 2 comprise the "Introduction," with opening statements by a number of Senators, followed by the presentations of other witnesses. The focus of these two parts is on such…

HAT-P-26b: A Neptune-mass exoplanet with a well-constrained heavy element abundance.

PubMed

Wakeford, Hannah R; Sing, David K; Kataria, Tiffany; Deming, Drake; Nikolov, Nikolay; Lopez, Eric D; Tremblin, Pascal; Amundsen, David S; Lewis, Nikole K; Mandell, Avi M; Fortney, Jonathan J; Knutson, Heather; Benneke, Björn; Evans, Thomas M

2017-05-12

A correlation between giant-planet mass and atmospheric heavy elemental abundance was first noted in the past century from observations of planets in our own Solar System and has served as a cornerstone of planet-formation theory. Using data from the Hubble and Spitzer Space Telescopes from 0.5 to 5 micrometers, we conducted a detailed atmospheric study of the transiting Neptune-mass exoplanet HAT-P-26b. We detected prominent H 2 O absorption bands with a maximum base-to-peak amplitude of 525 parts per million in the transmission spectrum. Using the water abundance as a proxy for metallicity, we measured HAT-P-26b's atmospheric heavy element content ([Formula: see text] times solar). This likely indicates that HAT-P-26b's atmosphere is primordial and obtained its gaseous envelope late in its disk lifetime, with little contamination from metal-rich planetesimals. Copyright © 2017, American Association for the Advancement of Science.

Induction of nuclear factor kappaB by the CD30 receptor is mediated by TRAF1 and TRAF2.

PubMed Central

Duckett, C S; Gedrich, R W; Gilfillan, M C; Thompson, C B

1997-01-01

CD30 is a lymphoid cell-specific surface receptor which was originally identified as an antigen expressed on Hodgkin's lymphoma cells. Activation of CD30 induces the nuclear factor kappaB (NF-kappaB) transcription factor. In this study, we define the domains in CD30 which are required for NF-kappaB activation. Two separate elements of the cytoplasmic domain which were capable of inducing NF-kappaB independently of one another were identified. The first domain (domain 1) mapped to a approximately 120-amino-acid sequence in the membrane-proximal region of the CD30 cytoplasmic tail, between residues 410 and 531. A second, more carboxy-terminal region (domain 2) was identified between residues 553 and 595. Domain 2 contains two 5- to 10-amino-acid elements which can mediate the binding of CD30 to members of the tumor necrosis factor receptor-associated factor (TRAF) family of signal transducing proteins. Coexpression of CD30 with TRAF1 or TRAF2 but not TRAF3 augmented NF-kappaB activation through domain 2 but not domain 1. NF-kappaB induction through domain 2 was inhibited by coexpression of either full-length TRAF3 or dominant negative forms of TRAF1 or TRAF2. In contrast, NF-kappaB induction by domain 1 was not affected by alterations in TRAF protein levels. Together, these data support a model in which CD30 can induce NF-kappaB by both TRAF-dependent and -independent mechanisms. TRAF-dependent induction of NF-kappaB appears to be regulated by the relative levels of individual TRAF proteins in the cell. PMID:9032281

Obligatory parthenogenesis and TE load: Bacillus stick insects and the R2 non-LTR retrotransposon.

PubMed

Bonandin, Livia; Scavariello, Claudia; Mingazzini, Valentina; Luchetti, Andrea; Mantovani, Barbara

2017-06-01

Transposable elements (TEs) are selfish genetic elements whose self-replication is contrasted by the host genome. In this context, host reproductive strategies are predicted to impact on both TEs load and activity. The presence and insertion distribution of the non-LTR retrotransposon R2 was here studied in populations of the strictly bisexual Bacillus grandii maretimi and of the obligatory parthenogenetic Bacillus atticus atticus. Furthermore, data were also obtained from the offspring of selected B. a. atticus females. At the population level, the gonochoric B. g. maretimi showed a significantly higher R2 load than the obligatory parthenogenetic B. a. atticus. The comparison with bisexual and unisexual Bacillus rossius populations showed that their values were higher than those recorded for B. a. atticus and similar, or even higher, than those of B. g. maretimi. Consistently, an R2 load reduction is scored in B. a. atticus offspring even if with a great variance. On the whole, data here produced indicate that in the obligatory unisexual B. a. atticus R2 is active and that mechanisms of molecular turnover are effective. Furthermore, progeny analyses show that, at variance of the facultative parthenogenetic B. rossius, the R2 activity is held at a lower rate. Modeling parental-offspring inheritance, suggests that in B. a. atticus recombination plays a major role in eliminating insertions rather than selection, as previously suggested for unisexual B. rossius progeny, even if in both cases a high variance is observed. In addition to this, mechanisms of R2 silencing or chances of clonal selection cannot be ruled out. © 2016 Institute of Zoology, Chinese Academy of Sciences.

PACE. A Program for Acquiring Competence in Entrepreneurship. Part II: Becoming an Entrepreneur. Unit B: Where to Locate the Business. Research and Development Series No. 194 B-2.

ERIC Educational Resources Information Center

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

This three-part curriculum for entrepreneurship education is primarily for postsecondary level, including four-year colleges and adult education, but it can be adapted for special groups or vocational teacher education. The emphasis of the seven instructional units in Part II is on establishing a business. Unit B focuses on choosing a business…

Synergetic Effect of Dy2O3 and Ca Co-Dopants towards Enhanced Coercivity of Rare Earth Abundant RE-Fe-B Magnets.

PubMed

Li, Yingfei; Tian, Na; Fan, Xiaodong; You, Caiyin; Pei, Wenli; Cheng, Zhenxiang

2017-12-13

Low coercivity is the main disadvantage of RE-Fe-B permanent magnets containing highly abundant rare earths (RE: La, Ce) from the application point of view, even though they exhibit many cost and resource advantages. In this work, an industrial mixed rare earth alloy (RE 100  = La 30.6 Ce 50.2 Pr 6.4 Nd 12.8 ) with a high amount of the more abundant elements was adopted to fabricate RE-Fe-B permanent magnets by means of mechanical alloying accompanied by post-annealing. A synergetic effect towards enhancing the coercivity was observed after co-doping with Dy 2 O 3 and Ca, with the coercivity increasing from 2.44 kOe to 11.43 kOe for co-dopant percentages of 7 wt.% Dy 2 O 3  + 2.3 wt.% Ca. Through analysis of the phase constituents and microstructure, it was determined that part of the Dy atoms entered the matrix of RE 2 Fe 14 B phase to enhance the magnetocrystalline anisotropy; due to the reductive effect of Ca on Dy 2 O 3 , nanocrystals of Dy-rich RE 2 Fe 14 B were present throughout the matrix, which could increase the resistance to domain wall movement. These are the dominant factors behind the improvement of the coercivity of the RE-Fe-B magnets with highly abundant RE elements.

Basic EMC Technology Advancement for C(3) Systems - SHIELD. Volume IV B. A Digital Computer Program for Computing Crosstalk between Shielded Cables

DTIC Science & Technology

1982-11-01

your organization , please notify RADC OBCT) Griffiss AFB NY 13441. This will assist us in maintaining a current mailing list. Do not return copies of...RMING ORGANIZATION NAME r AND ADDRESS 10. PROGRAM ELEMENT. PROJECT. TASK Southeastern Center for Electrical AREA6WORKUNITNUMBERS Engineering Education...The program requires that the input data groups be organized as shown in Table 1 where the number of unshielded wires is U and the number of shielded

Leeds-Lyon Symposium on Tribology ’The Tribology Design of Machine Elements’ (15th) 6-9 September 1988

DTIC Science & Technology

1988-08-01

bearing radius 6 ILuR Radial bl 󈧎 :radial clearance A- l a0 a a 1+ b2 U: bearing speed ,. hto p, : ar "ess. 9. Aiscocity b2 b1 Fig. 1 Bearing...priorarrangement for football/ rugby /hockey/cricket, with charges beingade dependent upon playing numbers and duration of time in use. A large sports pavilion

[Reconstructed ambient light extinction coefficient and its contribution factors in Beijing in January, 2010].

PubMed

Zhu, Li-Hua; Tao, Jun; Chen, Zhong-Ming; Zhao, Yue; Zhang, Ren-Jian; Cao, Jun-Ji

2012-01-01

Aerosol samples for PM2.5 were collected from 1st January to 31st January 2010, in Beijing. The concentrations of organic carbon, elemental carbon, water-solubile ions and soil elements of all particle samples were determined by thermal/optical carbon analyzer, ion chromatography and X-ray fluorescence spectrometer, respectively. The scattering coefficients (b(sp)), absorbing coefficients (b(ap)) and meteorological parameters for this period were also measured. Ambient light extinction coefficients were reconstructed by IMPROVE formula and were compared with measured light extinction coefficients. The results showed that the average mass concentration of PM2.5 was (144.3 +/- 89.1) microg x m(-3) during campaigning period. The average values of measured b(ap), b(sp) and extinction coefficient (b(ext)) were (67.4 +/- 54.3), (328.5 +/- 353.8) and (395.9 +/- 405.2) Mm(-1), respectively. IMPROVE formula is suitable for source apportionment of light extinction coefficient in campaign period. The average value of calculated b'(ext) was (611 +/- 503) Mm(-1) in January, 2010. The major contributors to ambient light extinction coefficients included (NH4) 2SO4 (24.6%), NH4NO3 (11.6%), OM (45.5%), EC (11.9%) and FS (6.4%), respectively.

Direct trans-activation of the human cyclin D2 gene by the oncogene product Tax of human T-cell leukemia virus type I.

PubMed

Huang, Y; Ohtani, K; Iwanaga, R; Matsumura, Y; Nakamura, M

2001-03-01

Cyclins are one of the pivotal determinants regulating cell cycle progression. We previously reported that the trans-activator Tax of human T-cell leukemia virus type I (HTLV-I) induces endogenous cyclin D2 expression along with cell cycle progression in a resting human T-cell line, Kit 225, suggesting a role of cyclin D2 in Tax-mediated cell cycle progression. The cyclin D2 gene has a typical E2F binding element, raising the possibility that induction of cyclin D2 expression is a consequence of cell cycle progression. In this study, we examined the role and molecular mechanism of induction of the endogenous human cyclin D2 gene by Tax. Introduction of p19(INK4d), a cyclin dependent kinase (CDK) inhibitor of the INK4 family specific for D-type CDK, inhibited Tax-mediated activation of E2F, indicating requirement of D-type CDK in Tax-mediated activation of E2F. Previously indicated E2F binding element and two NF-kappaB-like binding elements in the 1.6 kbp cyclin D2 promoter fragment had little, if any, effect on responsiveness to Tax. We found that trans-activation of the cyclin D2 promoter by Tax was mainly mediated by a newly identified NF-kappaB-like element with auxiliary contribution of a CRE-like element residing in sequences downstream of -444 which were by themselves sufficient for trans-activation by Tax. These results indicate that Tax directly trans-activates the cyclin D2 gene, resulting in growth promotion and perhaps leukemogenesis through activation of D-type CDK.

Crosstalk Reduction for High-Frequency Linear-Array Ultrasound Transducers Using 1–3 Piezocomposites With Pseudo-Random Pillars

PubMed Central

Yang, Hao-Chung; Cannata, Jonathan; Williams, Jay; Shung, K. Kirk

2013-01-01

The goal of this research was to develop a novel diced 1–3 piezocomposite geometry to reduce pulse–echo ring down and acoustic crosstalk between high-frequency ultrasonic array elements. Two PZT-5H-based 1–3 composites (10 and 15 MHz) of different pillar geometries [square (SQ), 45° triangle (TR), and pseudo-random (PR)] were fabricated and then made into single-element ultrasound transducers. The measured pulse–echo waveforms and their envelopes indicate that the PR composites had the shortest −20-dB pulse length and highest sensitivity among the composites evaluated. Using these composites, 15-MHz array subapertures with a 0.95λ pitch were fabricated to assess the acoustic crosstalk between array elements. The combined electrical and acoustical crosstalk between the nearest array elements of the PR array sub-apertures (−31.8 dB at 15 MHz) was 6.5 and 2.2 dB lower than those of the SQ and the TR array subapertures, respectively. These results demonstrate that the 1–3 piezocomposite with the pseudo-random pillars may be a better choice for fabricating enhanced high-frequency linear-array ultrasound transducers; especially when mechanical dicing is used. PMID:23143580

Micron-Scale Correlations Among Ti, P, Ce, and Y in Hadean Jack Hills Zircons

NASA Astrophysics Data System (ADS)

Hofmann, A. E.; Cavosie, A. J.; Valley, J. W.; Eiler, J. M.

2007-12-01

Detrital zircons and the inclusions found therein are our only mineralogical constraints on geologic events that occurred on the Hadean Earth. These zircons are commonly small (ca. <100 μm in the longest dimension) and preserve micron to sub-micron chemical zonations indicative of a dynamic petrological history. Trace elements within zircon are of particular interest because concentrations and ratios of these elements can provide information regarding chemical and physical conditions during zircon growth. In this study, we analyzed Hadean-age detrital zircons from Archean metasediment in the Jack Hills (Australia) using the Caltech Microanalysis Center Cameca NanoSIMS 50L. Trace elements analyzed included Ti, P, Ce, and Y. Ti- thermometry [1,2,3] can potentially constrain growth and/or re-equilibration temperatures of zircons; P, Ce, and Y are known to enter the zircon lattice by the coupled xenotime-type substitution mechanism: (Y, REE)3+ + P5+ = Zr4+ + Si4+ [5]. The 89Y/28Si ratio was observed to correlate with, and was used as a proxy for, cathodoluminescence (CL) banding. Growth features manifested in CL (e.g., sector, oscillatory zoning) were observed in all zircons analyzed. CL zones vary from <1 μm to several microns in width; therefore, the NanoSIMS---with a beam diameter resolved to ca. 250 nm on the sample surface when operating with an O- primary beam---is uniquely suited for this scale of analysis. Regions displaying CL banding were imaged as 20 x 20 μm areas. All elements were normalized to 28Si; 49Ti/28Si ratios were converted to [Ti] via calibration based on analyses of synthetic, high-Ti zircons (provided by B. Watson) that were independently analyzed on Caltech's JEOL JXA-8200 electron microprobe. We observe three types of relationships between trace element distribution and CL banding in the zircons imaged: 1) strong positive correlations between CL banding, P, Ce, and Ti; 2) subtle positive correlations between CL banding, P, Ce, and Ti; 3) no correlation between minor/trace elements and CL banding. Positive correlations between CL banding, 3+ cations, and [Ti] have previously been reported by Holden et al. [4]. In this study, gradients at least as sharp as a factor of ~3 in [Ti] are observed between adjacent CL bands in the strongly correlated images. These images also have the highest absolute concentrations of trace elements and display both sector and oscillatory zoning in CL. The correlations observed may be due to: temperature-dependent equilibrium partitioning of all trace elements during rapid cycles in growth temperature; episodic diffusion-limited enrichment of incompatible trace elements in the boundary layer melt adjacent to growing crystals; and/or kinetically controlled, non- equilibrium crystal-melt partitioning caused by trace element enrichments in the boundary layer melt surrounding fast-growing grains (e.g., [6]). We will discriminate between these alternatives based on quantitative relationships between relative enrichments of [Ti] and other trace elements. [1]Watson, E.B. & Harrison, T.M. (2005) Science 308, 841-844. [2]Watson, E.B., Wark, D.A., & Thomas, J.B. (2006) CMP 151, 413-433. [3]Ferry, J.M. & Watson, E.B. (2007) CMP 154, 429-437. [4] Holden, P. et al. (2005) Eos Trans. AGU 86 (52) Fall Meet. Suppl., Abstract V41F-1539. [5] Speer, J.A. (1982) Zircon. In Rev. Min. 5 (ed. P.H. Ribbe), 67-112. [6] Watson, E.B. (2004) GCA 68, 1473-1488.

Mechanical Four-Pole Parameters: Transmission Matrices

DTIC Science & Technology

1976-04-19

moment of inertia, it is pcssible to state that 1, = i2 ’jV 2 (127) ~ =v 2 ,(128) B, = B2 ,(129) el e2 (130) 28 1 -JA 0 0 P2 0 1 0 0 VM 0 1 j :(. 131 ...Eq. 129 now becomes + JCI ,2(1.32) so that F1 1 -JaM 0 0 F2 V, 0 1 0 0 V2 ~ :~ (133) B. 0 0o 1 Jcn B 2 1 2 3. Spring of Stiffness K in Cascade [Fig...transmission matrix is that of Eq. 131 in which the element - JaM has been replaced py - Za. 9. VALUES OF TRANSMISSION MATRICES (BERNOULLI-EUER BEANS

A Study of Thick-Target X-Ray Spectra Using Photonuclear Reactions

DTIC Science & Technology

1983-01-01

energy k will be given by kmln-BV1+(BEb/Mxc2)] (2) Where M Is the mass of the target nucleus, c is the velocity of light , and BE. , the binding...3-8 MeV (18,23,26). The energy B at which the cross section is a maximum is approximately 20 MeV for light elements (23,26). For heavy elements, E...Detailed inspection of the giant reaonance of photonuclear reactions in light elements reveals cross section maxima and minima, or "atructure

Bi-Linear Shear Deformable ANCF Shell Element Using Continuum Mechanics Approach

DTIC Science & Technology

2014-08-01

Lappeenranta University of Technology Skinnarilankatu 34, 53850 Lappeenranta, Finland Paramsothy Jayakumar US Army RDECOM TARDEC 6501 E. 11 Mile...2-0001 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Hiroki Yamashita; Antti Valkeapaa; Paramsothy Jayakumar ; Hiroyuki Sugiyama 5d...Valkeapää, A. I., Yamashita, H., Jayakumar , P. and Sugiyama, H., “Gradient Deficient Bi-Linear Plate Element Based on Absolute Nodal Coordinate

Ionic High-Pressure Form of Elemental Boron

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oganov, A.; Chen, J; Gatti, C

2009-01-01

This Letter presents the results of high-pressure experiments and ab initio evolutionary crystal structure predictions, and found a new boron phase that we named gamma-B28. This phase is comprised of icosahedral B12 clusters and B2 pairs in a NaCl-type arrangement, stable between 19 and 89 GPa, and exhibits evidence for charge transfer (for which our best estimate is delta approximately 0.48) between the constituent clusters to give (B2)delta+(B12)delta-. We have recently found that the same high-pressure boron phase may have given rise to the Bragg reflections reported by Wentorf in 1965 (ref. 1), although the chemical composition was not analysedmore » and the data (subsequently deleted from the Powder Diffraction File database) seems to not have been used to propose a structure model. We also note that although we used the terms 'partially ionic' and 'ionic' to emphasize the polar nature of the high-pressure boron phase and the influence this polarity has on several physical properties of the elemental phase, the chemical bonding in gamma-B28 is predominantly covalent.« less

Identification of alpha-enolase as a nuclear DNA-binding protein in the zona fasciculata but not the zona reticularis of the human adrenal cortex.

PubMed

Wang, Weiye; Wang, Lishan; Endoh, Akira; Hummelke, Geoffrey; Hawks, Christina L; Hornsby, Peter J

2005-01-01

In order to establish whether there are differences in DNA-binding proteins between zona fasciculata (ZF) and zona reticularis (ZR) cells of the human adrenal cortex, we prepared nuclear extracts from separated ZF and ZR cells. The formation of DNA-protein complexes was studied using an element in the first intron of the type I and type II 3beta-hydroxysteroid dehydrogenase genes (HSD3B1 and HSD3B2). Using the element in the HSD3B2 gene as a probe, a complex (C1) was formed with extracts from ZF cells but was formed only at a low level with ZR cell extracts. Another pair of complexes (C2/C3) was formed with both ZF and ZR cell extracts. The ZF-specific protein forming C1 was enriched by column chromatography on DEAE-Sepharose and carboxymethyl-Sepharose. Oligonucleotide competition analysis on the enriched fraction gave results consistent with those obtained on the unfractionated material. A further enrichment was brought about by passing the protein over an oligonucleotide affinity column based on the HSD3B2 element. The protein bound to the column was identified as alpha-enolase by mass spectrometry. Although alpha-enolase is a glycolytic enzyme, it binds to specific DNA sequences and has been found to be present in nuclei of various cell types. We performed immunohistochemistry on sections of adult human adrenal cortex and found alpha-enolase to be located in nuclei of ZF cells but to be predominantly cytoplasmic in ZR cells. Transfection of an alpha-enolase expression vector into NCI-H295R human adrenocortical cells increased HSD3B2 promoter activity, suggesting a possible functional role for this protein in regulation of HSD3B2 expression.

Reciprocal Loss of CArG-Boxes and Auxin Response Elements Drives Expression Divergence of MPF2-Like MADS-Box Genes Controlling Calyx Inflation

PubMed Central

Khan, Muhammad Ramzan; Hu, Jinyong; Ali, Ghulam Muhammad

2012-01-01

Expression divergence is thought to be a hallmark of functional diversification between homologs post duplication. Modification in regulatory elements has been invoked to explain expression divergence after duplication for several MADS-box genes, however, verification of reciprocal loss of cis-regulatory elements is lacking in plants. Here, we report that the evolution of MPF2-like genes has entailed degenerative mutations in a core promoter CArG-box and an auxin response factor (ARF) binding element in the large 1st intron in the coding region. Previously, MPF2-like genes were duplicated into MPF2-like-A and -B through genome duplication in Withania and Tubocapsicum (Withaninae). The calyx of Withania grows exorbitantly after pollination unlike Tubocapsicum, where it degenerates. Besides inflated calyx syndrome formation, MPF2-like transcription factors are implicated in functions both during the vegetative and reproductive development as well as in phase transition. MPF2-like-A of Withania (WSA206) is strongly expressed in sepals, while MPF2-like-B (WSB206) is not. Interestingly, their combined expression patterns seem to replicate the pattern of their closely related hypothetical progenitors from Vassobia and Physalis. Using phylogenetic shadowing, site-directed mutagenesis and motif swapping, we could show that the loss of a conserved CArG-box in MPF2-like-B of Withania is responsible for impeding its expression in sepals. Conversely, loss of an ARE in MPF2-like-A relaxed the constraint on expression in sepals. Thus, the ARE is an active suppressor of MPF2-like gene expression in sepals, which in contrast is activated via the CArG-box. The observed expression divergence in MPF2-like genes due to reciprocal loss of cis-regulatory elements has added to genetic and phenotypic variations in the Withaninae and enhanced the potential of natural selection for the adaptive evolution of ICS. Moreover, these results provide insight into the interplay of floral developmental and hormonal pathways during ICS development and add to the understanding of the importance of polyploidy in plants. PMID:22900049

[Permanent education in health: a review].

PubMed

Miccas, Fernanda Luppino; Batista, Sylvia Helena Souza da Silva

2014-02-01

To undertake a meta-synthesis of the literature on the main concepts and practices related to permanent education in health. A bibliographical search was conducted for original articles in the PubMed, Web of Science, LILACS, IBECS and SciELO databases, using the following search terms: "public health professional education", "permanent education", "continuing education", "permanent education health". Of the 590 articles identified, after applying inclusion and exclusion criteria, 48 were selected for further analysis, grouped according to the criteria of key elements, and then underwent meta-synthesis. The 48 original publications were classified according to four thematic units of key elements: 1) concepts, 2) strategies and difficulties, 3) public policies and 4) educational institutions. Three main conceptions of permanent education in health were found: problem-focused and team work, directly related to continuing education and education that takes place throughout life. The main strategies for executing permanent education in health are discussion, maintaining an open space for permanent education , and permanent education clusters. The most limiting factor is mainly related to directly or indirect management. Another highlight is the requirement for implementation and maintenance of public policies, and the availability of financial and human resources. The educational institutions need to combine education and service aiming to form critical-reflexive graduates. The coordination between health and education is based as much on the actions of health services as on management and educational institutions. Thus, it becomes a challenge to implement the teaching-learning processes that are supported by critical-reflexive actions. It is necessary to carry out proposals for permanent education in health involving the participation of health professionals, teachers and educational institutions. To undertake a meta-synthesis of the literature on the main concepts and practices related to permanent education in health. A bibliographical search was conducted for original articles in the PubMed, Web of Science, LILACS, IBECS and SciELO databases, using the following search terms: "public health professional education", "permanent education", "continuing education", "permanent education health". Of the 590 articles identified, after applying inclusion and exclusion criteria, 48 were selected for further analysis, grouped according to the criteria of key elements, and then underwent meta-synthesis. The 48 original publications were classified according to four thematic units of key elements: 1) concepts, 2) strategies and difficulties, 3) public policies and 4) educational institutions. Three main conceptions of permanent education in health were found: problem-focused and team work, directly related to continuing education and education that takes place throughout life. The main strategies for executing permanent education in health are discussion, maintaining an open space for permanent education, and permanent education clusters. The most limiting factor is mainly related to directly or indirect management. Another highlight is the requirement for implementation and maintenance of public policies, and the availability of financial and human resources. The educational institutions need to combine education and service aiming to form critical-reflexive graduates. The coordination between health and education is based as much on the actions of health services as on management and educational institutions. Thus, it becomes a challenge to implement the teaching-learning processes that are supported by critical-reflexive actions. It is necessary to carry out proposals for permanent education in health involving the participation of health professionals, teachers and educational institutions.

Optimum concentric circular array antenna with high gain and side lobe reduction at 5.8 GHz

NASA Astrophysics Data System (ADS)

Zaid, Mohammed; Rafiqul Islam, Md; Habaebi, Mohamed H.; Zahirul Alam, AHM; Abdullah, Khaizuran

2017-11-01

The significance of high gain directional antennas stems from the need to cope up with the everyday progressing wireless communication systems. Due to low gain of the widely used microstrip antenna, combining multiple antennas in proper geometry increases the gain with good directive property. Over other array forms, this paper uses concentric circular array configuration for its compact structure and inherent symmetry in azimuth. This proposed array is composed of 9 elements on FR-4 substrate, which is designed for WLAN applications at 5.8GHz. Antenna Magus software is used for synthesis, while CST software is used for optimization. The proposed array is designed with optimum inter-element spacing and number of elements achieving a high directional gain of 15.7 dB compared to 14.2 dB of available literature, with a high reduction in side lobe level of -17.6 dB.

The Use of Computer Games as an Educational Tool: Identification of Appropriate Game Types and Game Elements.

ERIC Educational Resources Information Center

Amory, Alan; Naicker, Kevin; Vincent, Jacky; Adams, Claudia

1999-01-01

Describes research with college students that investigated commercial game types and game elements to determine what would be suitable for education. Students rated logic, memory, visualization, and problem solving as important game elements that are used to develop a model that links pedagogical issues with game elements. (Author/LRW)

The Changing Culture of Childhood: A Perfect Storm

ERIC Educational Resources Information Center

Frost, Joe L.

2007-01-01

In this article, the author observes how a combination of interrelated elements are currently changing the face of the civilizing traditions of the U.S. education and forming a new culture of childhood. These include: (1) the standardization of education; (2) the dissolution of traditional spontaneous play; and (3) the growing specter of poverty…

Office Education Curriculum Guide Series. [Core Document.

ERIC Educational Resources Information Center

Sullivan, Carol

As one of a series of curriculum guides for office education programs in Texas, this guide contains units of instruction to assist in teaching the following objectives rated as necessary for the success of the program by experienced teachers across the state: (1) the essential elements common to all vocational programs and (2) the essential…

Uprising of Creation in Education

ERIC Educational Resources Information Center

Hatamleh, Habes Mohamed

2015-01-01

This research (Uprising of Creation in Education) aims at defining the importance of creativity in education, and its reflection on the elements of the educational process. Creativity is regarded an important element in the nations progress, which depends on the minds of their sons. Creativity became the language of the present age, after the…

Initial versus ongoing education: Perspectives of people with type 1 diabetes in 13 countries.

PubMed

Beran, David; Golay, Alain

2017-05-01

To understand the perspectives of people with type 1 diabetes with regards to the diabetes education they receive within the health system. Grounded Theory was used for the collection and analysis of data from interviews with 101 people with type 1 diabetes from 13 countries. There are two aspects to education, namely initial education received when diagnosed and the ongoing education people continue to receive. Within these two categories content and process of diabetes education are important as are factors linked to the healthcare worker and setting. Tangible elements are the "what" that is delivered and are the different skills and information needed for people to manage their diabetes. Process elements are the "how" this is delivered. Finally intangible elements are those, which were found to be specific to certain contexts and health professionals. These could be the hardest to replicate, but possibly the most important. Health systems can provide the tangible elements and organize themselves to have processes in place to deliver education. The challenge is how can the intangible elements be seen as important and developed and delivered to improve management, but also meet the needs of people with diabetes. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Effect of CoCl(2) treatment on major and trace elements metabolism and protein concentration in mice.

PubMed

Zaksas, Nataliya; Gluhcheva, Yordanka; Sedykh, Sergey; Madzharova, Maria; Atanassova, Nina; Nevinsky, Georgy

2013-01-01

Cobalt (Co) is a transition metal and an essential trace element, required for vitamin B(12) biosynthesis, enzyme activation and other biological processes, but toxic in high concentrations. There is lack of data for the effect of long-term Co(II) treatment on the concentrations of other trace elements. We estimate the influence of cobalt chloride (CoCl(2)) on the relative content of different metals in mouse plasma using two-jet arc plasmatron atomic emission and on the total protein content. On average, the content of different elements in the plasma of 2-month-old balb/c mice (control group) decreased in the order: Ca>Mg>Si>Fe>Zn>Cu≥Al≥B. The treatment of mice for 60 days with CoCl(2) (daily dose 125 mg/kg) did not appreciably change the relative content of Ca, Cu, and Zn, while a 2.4-fold statistically significant decrease in the content of B and significant increase in the content of Mg (1.4-fold), Al and Fe (2.0-fold) and Si (3.2-fold) was found. A detectable amount of Mo was observed only for two control mice, while the plasma of 9 out of 16 mice of the treated group contained this metal. The administration of Co made its concentration detectable in the plasma of all mice of the treated group, but the relative content varied significantly. The treatment led to a 2.2-fold decrease in the concentration of the total plasma protein. Chronic exposure to CoCl(2) affects homeostasis as well as the concentrations and metabolism of other essential elements, probably due to competition of Co ions for similar binding sites within cells, altered signal transduction and protein biosynthesis. Long-term treatment also leads to significant weight changes and reduces the total protein concentration. The data may be useful for an understanding of Co toxicity, its effect on the concentration of other metal ions and different physiological processes. Copyright © 2012 Elsevier GmbH. All rights reserved.

Regulatory elements involved in tax-mediated transactivation of the HTLV-I LTR.

PubMed

Seeler, J S; Muchardt, C; Podar, M; Gaynor, R B

1993-10-01

HTLV-I is the etiologic agent of adult T-cell leukemia. In this study, we investigated the regulatory elements and cellular transcription factors which function in modulating HTLV-I gene expression in response to the viral transactivator protein, tax. Transfection experiments into Jurkat cells of a variety of site-directed mutants in the HTLV-1 LTR indicated that each of the three motifs A, B, and C within the 21-bp repeats, the binding sites for the Ets family of proteins, and the TATA box all influenced the degree of tax-mediated activation. Tax is also able to activate gene expression of other viral and cellular promoters. Tax activation of the IL-2 receptor and the HIV-1 LTR is mediated through NF-kappa B motifs. Interestingly, sequences in the 21-bp repeat B and C motifs contain significant homology with NF-kappa B regulatory elements. We demonstrated that an NF-kappa B binding protein, PRDII-BF1, but not the rel protein, bound to the B and C motifs in the 21-bp repeat. PRDII-BF1 was also able to stimulate activation of HTLV-I gene expression by tax. The role of the Ets proteins on modulating tax activation was also studied. Ets 1 but not Ets 2 was capable of increasing the degree of tax activation of the HTLV-I LTR. These results suggest that tax activates gene expression by either direct or indirect interaction with several cellular transcription factors that bind to the HTLV-I LTR.

77 FR 58359 - Applications for New Awards; Race to the Top-Early Learning Challenge; Phase 2

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-20

... amended by section 1832(b) of Division B of Pub. L. 112-10, the Department of Defense and Full-Year... DEPARTMENT OF EDUCATION DEPARTMENT OF HEALTH AND HUMAN SERVICES Applications for New Awards; Race to the Top--Early Learning Challenge; Phase 2 AGENCY: Department of Education and Department of...

Novel Structure of Enterococcus faecium-Originated ermB-Positive Tn1546-Like Element in Staphylococcus aureus.

PubMed

Wan, Tsai-Wen; Hung, Wei-Chun; Tsai, Jui-Chang; Lin, Yu-Tzu; Lee, Hao; Hsueh, Po-Ren; Lee, Tai-Fen; Teng, Lee-Jene

2016-10-01

We determined the resistance determinants in 274 erythromycin-resistant methicillin-susceptible Staphylococcus aureus (MSSA) isolates during a 13-year period, 2000 to 2012. The resistance phenotypes, inducible macrolide-lincosamide-streptogramin (iMLS), constitutive MLS (cMLS), and macrolide-streptogramin (MS) resistance phenotypes, were examined by a double-disk diffusion D test. The ermB gene was more frequent (35%; 97/274) than ermC (27%; 75/274) or ermA (21%; 58/274). All 97 ermB-positive isolates harbored Tn551 and IS1216V The majority (89/97) of ermB-positive isolates displayed the cMLS phenotype and carried mobile element structure (MES)-like structures, which has been previously reported in sequence type 59 (ST59) methicillin-resistant S. aureus (MRSA). The remaining 8 ermB-carrying isolates, belonging to ST7 (n = 4), ST5 (n = 3), and ST59 (n = 1), were sasK intact and did not carry MES-like structures. Unlike a MES-like structure that was located on the chromosome, the ermB elements on sasK-intact isolates were located on plasmids by S1 nuclease pulsed-field gel electrophoresis (PFGE) analysis and conjugation tests. Sequence data for the ermB-containing region (14,566 bp) from ST59 NTUH_3874 revealed that the best match was a Tn1546-like element in plasmid pMCCL2 DNA (GenBank accession number AP009486) of Macrococcus caseolyticus Tn1546 is recognized as an enterococcal transposon and was known from the vancomycin resistance gene cluster in vancomycin-resistant Enterococcus (VRE). So far, acquisitions of Tn1546 in S. aureus have occurred in clonal complex 5 (CC5) MRSA, but not in MSSA. This is the first report that MSSA harbors an Enterococcus faecium-originated ermB-positive Tn1546-like element located on a plasmid. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

High temperature Ir segregation in Ir-B ceramics: Effect of oxygen presence on stability of IrB 2 and other Ir-B phases

DOE PAGES

Xie, Zhilin; Terracciano, Anthony C.; Cullen, David A.; ...

2015-05-13

The formation of IrB 2, IrB 1.35, IrB 1.1 and IrB monoboride phases in the Ir–B ceramic nanopowder was confirmed during mechanochemical reaction between metallic Ir and elemental B powders. The Ir–B phases were analysed after 90 h of high energy ball milling and after annealing of the powder for 72 h at 1050°C in vacuo. The iridium monoboride (IrB) orthorhombic phase was synthesised experimentally for the first time and identified by powder X-ray diffraction. Additionally, the ReB 2 type IrB 2 hexagonal phase was also produced for the first time and identified by high resolution transmission electron microscope. Irmore » segregation along disordered domains of the boron lattice was found to occur during high temperature annealing. Furthermore, these nanodomains may have useful catalytic properties.« less

34 CFR 300.202 - Use of amounts.

Code of Federal Regulations, 2011 CFR

2011-07-01

... this part; (2) Must be used only to pay the excess costs of providing special education and related... B of the Act to pay for all of the costs directly attributable to the education of a child with a... prevent an LEA from using Part B funds to pay for all of the costs directly attributable to the education...

34 CFR 300.202 - Use of amounts.

Code of Federal Regulations, 2010 CFR

2010-07-01

... this part; (2) Must be used only to pay the excess costs of providing special education and related... B of the Act to pay for all of the costs directly attributable to the education of a child with a... prevent an LEA from using Part B funds to pay for all of the costs directly attributable to the education...

75 FR 31810 - Information Collection for IDEIA Part B and C Child Counts; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-04

... education and related services for American Indian children aged 0 to 5 with disabilities on reservations... for special education and related services for Indian children aged 0 to 5 with disabilities on... children aged 0 to 2 covered by IDEIA Part C. In IDEIA Part B--Assistance for Education of All Children...

34 CFR 400.2 - What programs are governed by these regulations?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 407). (b) National discretionary programs. (1) Indian Vocational Education Program (34 CFR part 401). (2) Native Hawaiian Vocational Education Program (34 CFR part 402). (3) National Tech-Prep Education...). (8) National Network for Curriculum Coordination in Vocational and Technical Education (34 CFR part...

Dual DNA binding property of ABA insensitive 3 like factors targeted to promoters responsive to ABA and auxin.

PubMed

Nag, Ronita; Maity, Manas Kanti; Dasgupta, Maitrayee

2005-11-01

The ABA responsive ABI3 and the auxin responsive ARF family of transcription factors bind the CATGCATG (Sph) and TGTCTC core motifs in ABA and auxin response elements (ABRE and AuxRE), respectively. Several evidences indicate ABI3s to act downstream to auxin too. Because DNA binding domain of ABI3s shows significant overlap with ARFs we enquired whether auxin responsiveness through ABI3s could be mediated by their binding to canonical AuxREs. Investigations were undertaken through in vitro gel mobility shift assays (GMSA) using the DNA binding domain B3 of PvAlf (Phaseolus vulgaris ABI3 like factor) and upstream regions of auxin responsive gene GH3 (-267 to -141) and ABA responsive gene Em (-316 to -146) harboring AuxRE and ABRE, respectively. We demonstrate that B3 domain of PvAlf could bind AuxRE only when B3 was associated with its flanking domain B2 (B2B3). Such strict requirement of B2 domain was not observed with ABRE, where B3 could bind with or without being associated with B2. This dual specificity in DNA binding of ABI3s was also demonstrated with nuclear extracts of cultured cells of Arachis hypogea. Supershift analysis of ABRE and AuxRE bound nuclear proteins with antibodies raised against B2B3 domains of PvAlf revealed that ABI3 associated complexes were detectable in association with both cis elements. Competition GMSA confirmed the same complexes to bind ABRE and AuxRE. This dual specificity of ABI3 like factors in DNA binding targeted to natural promoters responsive to ABA and auxin suggests them to have a potential role in conferring crosstalk between these two phytohormones.

The 2D Hyperlink/Geocaching hybrid as a New Method for Improving Communication and Educational Delivery in Environmental Science

NASA Astrophysics Data System (ADS)

Graham, J.; Byrne, J. M.

2009-12-01

Geocaching is a game of hiding and locating caches (treasures), usually with the aid of a GPS-enabled device, and then posting the locations online for others to discover. Its remarkable success as a cultural phenomenon - transcending the traditional boundaries of age, gender, race and culture, while seamlessly combining the elements of technology, mental challenge, travel, geography, orienteering and entertainment - has been well documented. One would expect, therefore, that something so accessible and so physically, mentally and technologically engaging could also have great potential as an educational tool; specifically for the teaching of environmental science in situ. The attempts to date, however, have been disappointing. It will be the purpose of this poster to demonstrate a new and effective approach to educational environmental science-based geocaching; one which treats discreet elements of the living landscape as caches (rather than obstacles), and which combines several commonly available technologies so as to create a rich, immersive experience for viewers of many ages and backgrounds. Specifically, our poster will demonstrate how traditional geocaching methods can be dramatically improved, for the purposes of education, by combining it with 2D hyperlinking technologies in such a way as to allow the viewer to access a variety of different online and/or offline media elements - documentaries, texts, websites, animations, and images, while immersed in the physical environment to which they relate. It will be shown that this site-specific approach to environmental education has considerable potential for improving the meaningful dialogue between environmental scientists and the general public.

Soliton cellular automaton associated with Dn(1)-crystal B2,s

NASA Astrophysics Data System (ADS)

Misra, Kailash C.; Wilson, Evan A.

2013-04-01

A solvable vertex model in ferromagnetic regime gives rise to a soliton cellular automaton which is a discrete dynamical system in which site variables take on values in a finite set. We study the scattering of a class of soliton cellular automata associated with the U_q(D_n^{(1)})-perfect crystal B2, s. We calculate the combinatorial R matrix for all elements of B2, s ⊗ B2, 1. In particular, we show that the scattering rule for our soliton cellular automaton can be identified with the combinatorial R matrix for U_q(A_1^{(1)}) oplus U_q(D_{n-2}^{(1)})-crystals.

Transition metal complexes of quinolino[3,2-b]benzodiazepine and quinolino[3,2-b]benzoxazepine: synthesis, characterization, and antimicrobial studies.

PubMed

Basavaraju, B; Naik, Halehatty S Bhojya; Prabhakara, Mustur C

2007-01-01

The synthesis and characterization of title complexes of the ligand Quinolino[3,2-b]benzodiazepine (QBD) and Quinolino[3,2-b]benzoxazepine (QBO) are reported. The complexes have been characterized by elemental analysis, molar conductance, magnetic studies, IR, H1 NMR, and UV-visible studies. They have the stoichiometry [ML2C12], where M=Co(II)/Ni(II), L=QBD/QBO, and [MLC12], where M=Zn(II)/Cd(II), L=QBD/QBO. The antibacterial and antifungal activity of the metal complexes has been investigated. The complexes were found to have higher antimicrobial activity than the parent ligand.

Internet 2 Health Sciences Initiative.

ERIC Educational Resources Information Center

Simco, Greg

2003-01-01

The Internet 2 (I2) health sciences initiative (I2HSI) involves the formulation of applications and supporting technologies, and guidelines for their use in the health sciences. Key elements of I2HSI include use of visualization, collaboration, medical informatics, telemedicine, and educational tools that support the health sciences. Specific…

Trace element behavior in hydrothermal experiments: Implications for fluid processes at shallow depths in subduction zones

NASA Astrophysics Data System (ADS)

You, C.-F.; Castillo, P. R.; Gieskes, J. M.; Chan, L. H.; Spivack, A. J.

1996-05-01

Chemical evaluation of fluids affected during progressive water-sediment interactions provides critical information regarding the role of slab dehydration and/or crustal recycling in subduction zones. To place some constraints on geochemical processes during sediment subduction, reactions between décollement sediments and synthetic NaCl-CaCl 2 solutions at 25-350°C and 800 bar were monitored in laboratory hydrothermal experiments using an autoclave apparatus. This is the first attempt in a single set of experiments to investigate the relative mobilities of many subduction zone volatiles and trace elements but, because of difficulties in conducting hydrothermal experiments on sediments at high P-T conditions, the experiments could only be designed for a shallow (˜ 10 km) depth. The experimental results demonstrate mobilization of volatiles (B and NH 4) and incompatible elements (As, Be, Cs, Li, Pb, Rb) in hydrothermal fluids at relatively low temperatures (˜ 300°C). In addition, a limited fractionation of light from heavy rare earth elements (REEs) occurs under hydrothermal conditions. On the other hand, the high field strength elements (HFSEs) Cr, Hf, Nb, Ta, Ti, and Zr are not mobile in the reacted fluids. The observed behavior of volatiles and trace elements in hydrothermal fluids is similar to the observed enrichment in As, B, Cs, Li, Pb, Rb, and light REEs and depletion in HFSEs in arc magmas relative to magmas derived directly from the upper mantle. Thus, our work suggests a link between relative mobilities of trace elements in hydrothermal fluids and deep arc magma generation in subduction zones. The experimental results are highly consistent with the proposal that the addition of subduction zone hydrous fluids to the subarc mantle, which has been depleted by previous melting events, can produce the unique characteristics of arc magmas. Moreover, the results suggest that deeply subducted sediments may no longer have the composition necessary to generate the other distinct characteristics, such as the B-δ 11 B and B- 10Be systematics, of arc lavas. Finally, the mobilization of B, Cs, Pb, and light REEs relative to heavy REEs in the hydrothermal fluids fractionate the ratios of B/Be, B/Nb, Cs/Rb, Pb/Ce, La/Ba and LREE/HREE, which behave conservatively during normal magmatic processes. These results demonstrate that the composition of slab-derived fluids has great implications for the recycling of elements; not only in arc magmas but also in mantle plumes.

Melt inclusion evidence for a volatile-enriched (H2O, Cl, B) component in parental magmas of Gorgona Island komatiites

NASA Astrophysics Data System (ADS)

Kamenetsky, V.; Sobolev, A.; McDonough, W.

2003-04-01

Late Cretaceous komatiites of Gorgona Island are unambiguous samples of ultra-mafic melts related to a hot and possibly 'wet' mantle plume. Despite significant efforts in studying komatiites, their volatile abundances remain largely unknown because of significant alteration of rocks and lack of fresh glasses. This work presents major, trace and volatile element data for 22 partially homogenised (at 1275oC and 1 bar pressure) melt inclusions in olivine (Fo 90.5-91.5) from a Gorgona Isl. komatiite (# Gor 94-3). Major element compositions (except FeO which is notably lower by up to 5 wt% as a result of post-entrapment re-equilibration) and most lithophile trace elements of melt inclusions are indistinguishable from the whole rock komatiites. With the exception of three inclusions that have low Na, H2O, Cl, F and S (likely compromised and degassed during heating) most compositions are characterised by relatively constant and high volatile abundances (H2O 0.4-0.8 wt%, Cl 0.02-0.03 wt%, B 0.8-1.4 ppm). These are interpreted as representative of original volatiles in parental melts because they correspond to the internal volatile pressure in the closed inclusions significantly exceeding 1 bar pressure of heating experiment. Although H2O is strongly enriched (PM-normalised H2O/Ce 10-17) its concentrations correlate well with many elements (e.g. Yb, Er, Y, Ti, Sr, Be). Other positive anomalies on the overall depleted (La/Sm 0.26-0.33) PM normalized compositional spectra of melt inclusions are shown by B (B/K 2.4-5.4) and Cl (Cl/K 11-16). Compositions of melt inclusions, when corrected for Fe loss and recalculated in equilibrium with host olivine, have high MgO (15.4-16.4 wt%; Mg# of 74) and substantial H2O (0.4-0.6 wt%) contents. This together with the data on other 'enriched' elements argues for the presence of previously unknown volatile-enriched component in the parental melts of Gorgona Isl. komatiites. We discuss contamination of magmas by altered oceanic crust in the plumbing system, the involvement of volatile-rich subduction related component(s) in the mantle source, and the geochemical control from residual garnet during the generation of komatiite primary melts.

Atomic weights of the elements 2009 (IUPAC technical report)

USGS Publications Warehouse

Wieser, M.E.; Coplen, T.B.

2011-01-01

The biennial review of atomic-weight determinations and other cognate data has resulted in changes for the standard atomic weights of 11 elements. Many atomic weights are not constants of nature, but depend upon the physical, chemical, and nuclear history of the material. The standard atomic weights of 10 elements having two or more stable isotopes have been changed to reflect this variability of atomic-weight values in natural terrestrial materials. To emphasize the fact that these standard atomic weights are not constants of nature, each atomic-weight value is expressed as an interval. The interval is used together with the symbol [a; b] to denote the set of atomic-weight values, Ar(E), of element E in normal materials for which a ≤ Ar(E) ≤ b. The symbols a and b denote the bounds of the interval [a; b]. The revised atomic weight of hydrogen, Ar(H), is [1.007 84; 1.008 11] from 1.007 94(7); lithium, Ar(Li), is [6.938; 6.997] from 6.941(2); boron, Ar(B), is [10.806; 10.821] from 10.811(7); carbon, Ar(C), is [12.0096; 12.0116] from 12.0107(8); nitrogen, Ar(N), is [14.006 43; 14.007 28] from 14.0067(2); oxygen, Ar(O), is [15.999 03; 15.999 77] from 15.9994(3); silicon, Ar(Si), is [28.084; 28.086] from 28.0855(3); sulfur, Ar(S), is [32.059; 32.076] from 32.065(2); chlorine, Ar(Cl), is [35.446; 35.457] from 35.453(2); and thallium, Ar(Tl), is [204.382; 204.385] from 204.3833(2). This fundamental change in the presentation of the atomic weights represents an important advance in our knowledge of the natural world and underscores the significance and contributions of chemistry to the well-being of humankind in the International Year of Chemistry 2011. The standard atomic weight of germanium, Ar(Ge), was also changed to 72.63(1) from 72.64(1).

Laser Setup for Volume Diffractive Optical Elements Recording in Photo-Thermo-Refractive Glass

DTIC Science & Technology

2016-04-14

Total Number: PERCENT_SUPPORTEDNAME FTE Equivalent: Total Number: PERCENT_SUPPORTEDNAME FTE Equivalent: Total Number: Sub Contractors (DD882) Names of...3 1b 2 3 a b Fig. 14. Schematic of a DBR (a) and DFB (b) lasers in Yb doped PTR glass. 1a and 1b – dichroic beam splitters with HR at 1066 nm and HT

7 CFR 2.63 - Deputy Under Secretary for Research, Education, and Economics.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Economics. 2.63 Section 2.63 Agriculture Office of the Secretary of Agriculture DELEGATIONS OF AUTHORITY BY... Under Secretary for Research, Education, and Economics § 2.63 Deputy Under Secretary for Research, Education, and Economics. Pursuant to § 2.21(a), subject to reservations in § 2.21(b), and subject to policy...

7 CFR 2.63 - Deputy Under Secretary for Research, Education, and Economics.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Economics. 2.63 Section 2.63 Agriculture Office of the Secretary of Agriculture DELEGATIONS OF AUTHORITY BY... Under Secretary for Research, Education, and Economics § 2.63 Deputy Under Secretary for Research, Education, and Economics. Pursuant to § 2.21(a), subject to reservations in § 2.21(b), and subject to policy...

7 CFR 2.63 - Deputy Under Secretary for Research, Education, and Economics.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Economics. 2.63 Section 2.63 Agriculture Office of the Secretary of Agriculture DELEGATIONS OF AUTHORITY BY... Under Secretary for Research, Education, and Economics § 2.63 Deputy Under Secretary for Research, Education, and Economics. Pursuant to § 2.21(a), subject to reservations in § 2.21(b), and subject to policy...

7 CFR 2.63 - Deputy Under Secretary for Research, Education, and Economics.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Economics. 2.63 Section 2.63 Agriculture Office of the Secretary of Agriculture DELEGATIONS OF AUTHORITY BY... Under Secretary for Research, Education, and Economics § 2.63 Deputy Under Secretary for Research, Education, and Economics. Pursuant to § 2.21(a), subject to reservations in § 2.21(b), and subject to policy...

7 CFR 2.63 - Deputy Under Secretary for Research, Education, and Economics.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Economics. 2.63 Section 2.63 Agriculture Office of the Secretary of Agriculture DELEGATIONS OF AUTHORITY BY... Under Secretary for Research, Education, and Economics § 2.63 Deputy Under Secretary for Research, Education, and Economics. Pursuant to § 2.21(a), subject to reservations in § 2.21(b), and subject to policy...

Analysis of tandem E-box motifs within human Complement receptor 2 (CR2/CD21) promoter reveals cell specific roles for RP58, E2A, USF and localized chromatin accessibility.

PubMed

Cruickshank, Mark N; Dods, James; Taylor, Rhonda L; Karimi, Mahdad; Fenwick, Emily J; Quail, Elizabeth A; Rea, Alexander J; Holers, V Michael; Abraham, Lawrence J; Ulgiati, Daniela

2015-07-01

Complement receptor 2 (CR2/CD21) plays an important role in the generation of normal B cell immune responses. As transcription appears to be the prime mechanism via which surface CR2/CD21 expression is controlled, understanding transcriptional regulation of this gene will have broader implications to B cell biology. Here we report opposing, cell-context specific control of CR2/CD21 promoter activity by tandem E-box elements, spaced 22 bp apart and within 70 bp of the transcription initiation site. We have identified E2A and USF transcription factors as binding to the distal and proximal E-box sites respectively in CR2-positive B-cells, at a site that is hypersensitive to restriction enzyme digestion compared to non-expressing K562 cells. However, additional unidentified proteins have also been found to bind these functionally important elements. By utilizing a proteomics approach we have identified a repressor protein, RP58, binding the distal E-box motif. Co-transfection experiments using RP58 overexpression constructs demonstrated a specific 10-fold repression of CR2/CD21 transcriptional activity mediated through the distal E-box repressor element. Taken together, our results indicate that repression of the CR2/CD21 promoter can occur through one of the E-box motifs via recruitment of RP58 and other factors to bring about a silenced chromatin context within CR2/CD21 non-expressing cells. Copyright © 2015 Elsevier Ltd. All rights reserved.

Elective single-embryo transfer: persuasive communication strategies can affect choice in a young British population.

PubMed

van den Akker, O B A; Purewal, S

2011-12-01

This study tested the effectiveness of the framing effect and fear appeals to inform young people about the risks of multiple births and the option of selecting elective single-embryo transfer (eSET). A non-patient student sample (age (mean±SD) 23±5.5 years; n=321) were randomly allocated to one of seven groups: (1) framing effect: (1a) gain and (1b) loss frame; (2) fear appeal: (2a) high, (2b) medium and (2c) low fear; or (3) a control group: (3a) education and (3b) non-education. The primary outcome measure was the Attitudes towards Single Embryo Transfer questionnaire, before exposure to the messages (time 1) and immediately afterwards (time 2). Results revealed participants in the high fear, medium fear and gain condition demonstrated the most positive and significant differences (P<0.001 to P<0.05) in their knowledge, hypothetical intentions and modest changes in attitudes towards eSET than the low fear, loss frame and education and non-education messages. The results demonstrate that the use of complex persuasive communication techniques on a student population to promote immediate and hypothetical eSET preferences is more successful at promoting eSET than merely reporting educational content. Future research should investigate its application in a clinical population. A multiple pregnancy is a health risk to both infant and mother following IVF treatment. The aims of this study were to test the effectiveness of two persuasive communication techniques (the framing effect and fear appeals) to inform young people about the risks of multiple births and the hypothetical option of selecting elective single-embryo transfer (eSET) (i.e., only one embryo is transferred to the uterus using IVF treatment). A total of 321 non-patient student sample (mean age 23) were randomly allocated to read a message from one of seven groups: (1) framing effect: (1a) gain and (1b) loss frame; (2) fear appeal: (2a) high, (2b) medium and (2c) low fear; or (3) a control group: education (3a) and (3b) non-education. Participants completed the Attitudes towards Single Embryo Transfer questionnaire, before exposure to the messages (time 1) and immediately afterwards (time 2). Results revealed that participants in the high fear, medium fear and gain condition demonstrated the most positive and significant differences in their knowledge, hypothetical intentions and modest changes in attitudes towards eSET than the low fear, loss frame and education and non-education messages. This study recommends that health promotion based on the framing effect and fear appeals should be tested in clinical (patient) samples in the future. Copyright © 2011 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

Toward more complete magnetic gradiometry with the Swarm mission

NASA Astrophysics Data System (ADS)

Kotsiaros, Stavros

2016-07-01

An analytical and numerical analysis of the spectral properties of the gradient tensor, initially performed by Rummel and van Gelderen (Geophys J Int 111(1):159-169, 1992) for the gravity potential, shows that when the tensor elements are grouped into sets of semi-tangential and pure-tangential parts, they produce almost identical signal content as the normal element. Moreover, simple eigenvalue relations can be derived between these sets and the spherical harmonic expansion of the potential. This theoretical development generally applies to any potential field. First, the analysis of Rummel and van Gelderen (1992) is adapted to the magnetic field case and then the elements of the magnetic gradient tensor are estimated by 2 years of Swarm data and grouped into \\varvec{Γ }^{(1)} = {[\\varvec{nabla } {{B}}]_{rθ },[\\varvec{nabla } {{B}}]_{r\\varphi }} resp. \\varvec{Γ }^{(2)} = {[\\varvec{nabla } {{B}}]_{θ θ }-[\\varvec{nabla } {{B}}]_{\\varphi \\varphi }, 2[\\varvec{nabla } {{B}}]_{θ \\varphi }}. It is shown that the estimated combinations \\varvec{Γ }^{(1)} and \\varvec{Γ }^{(2)} produce similar signal content as the theoretical radial gradient \\varvec{Γ }^{(0)} = {[\\varvec{nabla } {{B}}]_{rr}}. These results demonstrate the ability of multi-satellite missions such as Swarm, which cannot directly measure the radial gradient, to retrieve similar signal content by means of the horizontal gradients. Finally, lithospheric field models are derived using the gradient combinations \\varvec{Γ }^{(1)} and \\varvec{Γ }^{(2)} and compared with models derived from traditional vector and gradient data. The model resulting from \\varvec{Γ }^{(1)} leads to a very similar, and in particular cases improved, model compared to models retrieved by using approximately three times more data, i.e., a full set of vector, North-South and East-West gradients. This demonstrates the high information content of \\varvec{Γ }^{(1)}.

The Constituent Elements of Comparative Education in Japan: A Comparison with North America

ERIC Educational Resources Information Center

Yamada, Shoko

2015-01-01

This article, with the aim of identifying elements that constitute the characteristics of an academic space within comparative education, analyzes how comparative education has been discussed and practiced in Japan, based on a questionnaire completed by 264 members of the Japan Comparative Education Society and classification of articles published…

Aristotelian Elements in Nietzsche's Work Related to the Philosophy of Education

ERIC Educational Resources Information Center

Triantari, Sotiria A.

2011-01-01

In the author's opinion Nietzsche has adopted the three Aristotelian factors, i.e., logic, learning and experience, showing the nihilistic element in the educational system of his days. By means of the term "formal education", Nietzsche implies the education comprises the development of the intellectual faculties of the learner. According to…

Problem-Based Educational Game Becomes Student-Centered Learning Environment

ERIC Educational Resources Information Center

Rodkroh, Pornpimon; Suwannatthachote, Praweenya; Kaemkate, Wannee

2013-01-01

Problem-based educational games are able to provide a fun and motivating environment for teaching and learning of certain subjects. However, most educational game models do not address the learning elements of problem-based educational games. This study aims to synthesize and to propose the important elements to facilitate the learning process and…

In search of the elusive IrB 2: Can mechanochemistry help?

DOE PAGES

Xie, Zhilin; Blair, Richard G.; Orlovskaya, Nina; ...

2015-10-20

We produced hexagonal ReB 2-type IrB 2 diboride and orthorhombic IrB monoboride phases, that were previously unknown and saw them produced by mechanochemical syntheses. High energy ball milling of elemental Ir and B powder for 30 h, followed by annealing of the powder at 1050 °C for 48 h, resulted in the formation of the desired phases. Both traditional laboratory and high resolution synchrotron X-ray diffraction (XRD) analyses were used for phase identification of the synthesized powder. Additionally, scanning electron microscopy and transmission electron microscopy were employed, along with XRD, to further characterize the microstructure of the phases produced.

In search of the elusive IrB 2: Can mechanochemistry help?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xie, Zhilin; Blair, Richard G.; Orlovskaya, Nina

We produced hexagonal ReB 2-type IrB 2 diboride and orthorhombic IrB monoboride phases, that were previously unknown and saw them produced by mechanochemical syntheses. High energy ball milling of elemental Ir and B powder for 30 h, followed by annealing of the powder at 1050 °C for 48 h, resulted in the formation of the desired phases. Both traditional laboratory and high resolution synchrotron X-ray diffraction (XRD) analyses were used for phase identification of the synthesized powder. Additionally, scanning electron microscopy and transmission electron microscopy were employed, along with XRD, to further characterize the microstructure of the phases produced.

Bibliography of Soviet Laser Developments, Number 77, May - June 1985.

DTIC Science & Technology

1986-09-01

B . CONTRACT OR GRANT NUMBER(S) 9. PERFORMING ORGANIZATION NAME AND ADDRESS I0. PROGRAM ELEMENT. PROJECT, TASK Defense Intelligence Agency AREA...TABLE OF CONTENTS I. BASIC RESEARCH A. Solid State Lasers 1. Crystal a. Miscellaneous ................... 1 b . Ruby .. . . . . . . .. . . . . . - c...LiF ............................. 1 2. Rare Earth a. Miscellaneous .......... .. . 1 b . Nd3+ . .. . . . .. . .0 . . . . c. Er3

EFFECTS OF LASER RADIATION ON MATTER. LASER PLASMA: Pattern of the expansion of laser plasmas of various elements in a magnetic field

NASA Astrophysics Data System (ADS)

Bryunetkin, B. A.; Begimkulov, U. Sh; Dyakin, V. M.; Koldashov, G. A.; Repin, A. Yu; Stupitskiĭ, E. L.; Faenov, A. Ya

1993-02-01

The expansion of laser plasmas of the elements Be, Al, Cu, and Pb in a static transverse magnetic field B<=2.7 T has been studied experimentally. The plasma was produced by a ruby laser at a power density no greater than 1012 W/cm2. For all the elements, a characteristic "two-petal" expansion pattern is observed. At a certain distance from the target, the two petals coalesce into a narrow jet. The radius of curvature of the petals and the position of the coalescence point depend on the field strength and the atomic weight of the element.

Trace element and petrologic clues to the formation of forsterite-bearing Ca-Al-rich inclusions in the Allende meteorite

NASA Astrophysics Data System (ADS)

Wark, D. A.; Boynton, W. V.; Keays, R. R.; Palme, H.

1987-03-01

This work presents new trace element and petrographic data for three forsterite-bearing, Ca-Al-rich inclusions from the Allende meteorite: TE, 818a, and 110-A. Such inclusions form a continuum with Type B1 and B2 Ca-Al-rich inclusions (CAIs), and the authors refer to them as "Type B3" CAIs. Textures, mineral chemistries, crystal-chemically fractionated REE patterns, and other properties suggest that Type B3 crystallized from partly molten evaporative residues. They also present evidence that 818a was strongly re-heated and modified in the nebula after its initial crystallization: it consists of a core of coarse-grained Ti-Al-pyroxene (Tpx), forsterite, spinel and metal grains and a thick, surrounding mantle of melilite.

Magnetic properties of bulk, and rapidly solidified nanostructured (Nd 1-xCe x) 2Fe 14-yCo yB ribbons

DOE PAGES

Pathak, Arjun K.; Khan, M.; Gschneidner, Jr., K. A.; ...

2015-11-06

Magnetic properties of Ce and Co co-doped (Nd 1-xCe x) 2Fe 14-yCo yB compounds have been investigated both in bulk polycrystalline and rapidly solidified nanostructured ribbon forms. For certain Ce concentrations the materials exhibit spin re-orientation transitions below 140 K. The Curie temperatures, saturation magnetizations, and other magnetic properties relevant for applications as permanent magnets are controlled by Ce and Co substitutions for Nd and Fe, respectively. Most importantly, the results show that Ce, Co co-doped compounds are excellent replacements for several Dy-based high performance permanent magnets (dysprosium is one of the critical elements and is, therefore, in short supply).more » As a result, the high temperature (>375 K) magnetic properties for Nd–Ce–Fe–Co–B based alloys show promise not only as a replacement for Dy-doped Nd 2Fe 14B permanent magnets, but the new alloys also require significantly lower amounts of Nd, which too is the critical element that can be replaced by a more abundant Ce.« less

Thermal analysis, phase equilibria, and superconducting properties in magnesium boride and carbon doped magnesium boride

NASA Astrophysics Data System (ADS)

Bohnenstiehl, Scot David

In this work, the low temperature synthesis of MgB2 from Mg/B and MgH2/B powder mixtures was studied using Differential Scanning Calorimetry (DSC). For the Mg/B powder mixture, two exothermic reaction events were observed and the first reaction event was initiated by the decomposition of Mg(OH)2 on the surface of the magnesium powder. For the MgH 2/B powder mixture, there was an endothermic event at ˜375 °C (the decomposition of MgH2 into H2 and Mg) and an exothermic event ˜600 °C (the reaction of Mg and B). The Kissinger analysis method was used to estimate the apparent activation energy of the Mg and B reaction using DSC data with different furnace ramp rates. The limitations of MgB2 low temperature synthesis led to the development of a high pressure induction furnace that was constructed using a pressure vessel and an induction heating power supply. The purpose was to not only synthesize more homogeneous MgB2 samples, but also to determine whether MgB2 melts congruently or incongruently. A custom implementation of the Smith Thermal Analysis method was developed and tested on aluminum and AlB2, the closest analogue to MgB2. Measurements on MgB2 powder and a high purity Mg/B elemental mixture confirmed that MgB2 melts incongruently and decomposes into a liquid and MgB4 at ˜1445 °C at 10 MPa via peritectic decomposition. Another measurement using a Mg/B elemental mixture with impure boron suggested that ˜0.7 wt% carbon impurity in the boron raised the incongruent melting temperature to ˜1490-1500 °C. Lastly, the solubility limit for carbon in MgB2 was studied by making samples from B4C and Mg at 1530 °C, 1600 °C and 1700 °C in the high pressure furnace. All three samples had three phases: Mg, MgB2C2, and carbon doped MgB2. The MgB 2C2 and carbon doped MgB2 grain size increased with temperature and the 1700 °C sample had needle-like grains for both phases. The presence of the ternary phase, MgB2C2, suggested that the maximum doping limit for carbon in MgB2 had been reached. The 1530 °C sample was characterized by Electron Probe Microanalysis at the University of Oregon and the average carbon concentration was estimated to be ˜5.9 at%. Further investigation using TEM found MgO inclusions in the 1530 °C sample which were not detected with X-ray diffraction.

Associations between maternal level of education and occupational status with placental glucocorticoid regeneration and sensitivity.

PubMed

Räikkönen, Katri; O'Reilly, James R; Pesonen, Anu-Katriina; Kajantie, Eero; Villa, Pia; Laivuori, Hannele; Hämäläinen, Esa; Seckl, Jonathan R; Reynolds, Rebecca M

2014-08-01

Low socio-economic status (SES) is associated with increased disease risk in the involved and the next generation. The effects of low maternal SES on the offspring may be initiated prenatally. We hypothesized that fetoplacental glucocorticoid exposure might mediate the links. We examined associations between maternal level of education and occupational status (used as indices of SES) and placental expression of genes involved in glucocorticoid exposure and transfer between the mother and foetus. Placental biopsies were obtained from 67 healthy women (age 32.2 ± 5.3 years) with singleton, term pregnancies without obstetric complications who participated in a prospective Prediction and Prevention of Preeclampsia (PREDO) study. Level of education was self-reported, and occupational status was extracted from hospital records. Relative glucocorticoid receptor (GR; NR3C1), mineralocorticoid receptor (MR; NR3C2) and 11-beta-hydroxysteroid dehydrogenase type 1 (HSD11B1) and 2 (HSD11B2) mRNA levels were quantified by real-time PCR. Placental GR and HSD11B1 expression increased with decreasing maternal education (unadjusted P-values for linear trend = 0.04 and 0.02 and adjusted P-values = 0.06 and 0.09, respectively). Mothers with primary/secondary education had 52.9% (95% CI, 6.2-99.6, P = 0.03, adjusted P = 0.05) and 79.6% (95% CI, 6.5-153.6, P = 0.03, adjusted P = 0.09) higher GR and HSD11B1 mRNA levels compared with mothers with tertiary education. There were no other significant associations. Lower maternal level of education is associated with increased placental GR and HSD11B1 gene expression. This combination may regenerate active glucocorticoids in placenta and increase placental sensitivity to glucocorticoids, potentially leading to greater placental and foetal glucocorticoid exposure. © 2014 John Wiley & Sons Ltd.

Influence of socio-demographic, labour and professional factors on nursing perception concerning practice environment in Primary Health Care.

PubMed

Parro Moreno, Ana; Serrano Gallardo, Pilar; Ferrer Arnedo, Carmen; Serrano Molina, Lucía; de la Puerta Calatayud, M Luisa; Barberá Martín, Aurora; Morales Asencio, José Miguel; de Pedro Gómez, Joan

2013-11-01

To analyze the perception of nursing professionals of the Madrid Primary Health Care environment in which they practice, as well as its relationship with socio-demographic, work-related and professional factors. Cross-sectional, analytical, observational study. Questionnaire sent to a total of 475 nurses in Primary Health Care in Madrid (former Health Care Areas 6 and 9), in 2010. Perception of the practice environment using the Practice Environment Scale of the Nursing Work Index (PES-NWI) questionnaire, as well as; age; sex; years of professional experience; professional category; Health Care Area; employment status and education level. There was a response rate of 69.7% (331). The raw score for the PES-NWI was: 81.04 [95%CI: 79.18-82.91]. The factor with the highest score was "Support from Managers" (2.9 [95%CI: 2.8-3]) and the lowest "Workforce adequacy" (2.3 [95%CI: 2.2-2.4]). In the regression model (dependent variable: raw score in PES-NWI), adjusted by age, sex, employment status, professional category (coefficient B=6.586), and years worked at the centre (coefficient B=2.139, for a time of 0-2 years; coefficient B=7.482, for 3-10 years; coefficient B=7.867, for over 20 years) remained at p≤0.05. The support provided by nurse managers is the most highly valued factor in this practice environment, while workforce adequacy is perceived as the lowest. Nurses in posts of responsibility and those possessing a higher degree of training perceive their practice environment more favourably. Knowledge of the factors in the practice environment is a key element for health care organizations to optimize provision of care and to improve health care results. Copyright © 2012 Elsevier España, S.L. All rights reserved.

Comparison of the element composition in several plant species and their substrate from a 1500000-km2 area in Northern Europe.

PubMed

Reimann, C; Koller, F; Frengstad, B; Kashulina, G; Niskavaara, H; Englmaier, P

2001-10-20

Leaves of 9 different plant species (terrestrial moss represented by: Hylocomium splendens and Pleurozium schreberi; and 7 species of vascular plants: blueberry, Vaccinium myrtillus; cowberry, Vaccinium titis-idaea; crowberry, Empetrum nigrum; birch, Betula pubescens; willow, Salix spp.; pine, Pinus sylvestris and spruce, Picea abies) have been collected from up to 9 catchments (size 14-50 km2) spread over a 1500000 km2 area in Northern Europe. Soil samples were taken of the O-horizon and of the C-horizon at each plant sample site. All samples were analysed for 38 elements (Ag, Al, As, B, Ba, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, Hg, K, Li, Mg, Mn, Mo, Na, Ni, P, Pb, Rb, S, Sb, Sc, Se, Si, Sn, Sr, Th, Tl, U, V, Y, Zn and Zr) by ICP-MS, ICP-AES or CV-AAS (for Hg-analysis) techniques. The concentrations of some elements vary significantly between different plants (e.g. Cd, V, Co, Pb, Ba and Y). Other elements show surprisingly similar levels in all plants (e.g. Rb, S, Cu, K, Ca, P and Mg). Each group of plants (moss, shrubs, deciduous and conifers) shows a common behaviour for some elements. Each plant accumulates or excludes some selected elements. Compared to the C-horizon, a number of elements (S, K, B, Ca, P and Mn) are clearly enriched in plants. Elements showing very low plant/C-horizon ratios (e.g. Zr, Th, U, Y, Fe, Li and Al) can be used as an indicator of minerogenic dust. The plant/O-horizon and O-horizon/C-horizon ratios show that some elements are accumulated in the O-horizon (e.g. Pb, Bi, As, Ag, Sb). Airborne organic material attached to the leaves can thus, result in high values of these elements without any pollution source.

How mental health nurses improve their critical thinking through problem-based learning.

PubMed

Hung, Tsui-Mei; Tang, Lee-Chun; Ko, Chen-Ju

2015-01-01

Critical thinking has been regarded as one of the most important elements for nurses to improve quality of patient care. The aim of this study was to use problem-based learning (PBL) as a method in a continuing education program to evaluate nurses' critical thinking skills. A quasiexperimental study design was carried out. The "Critical Thinking Disposition Inventory" in Chinese was used for data collection. The results indicated significant improvement after PBL continuous education, notably in the dimensions of systematic analysis and curiosity. Content analysis extracted four themes: (a) changes in linear thinking required, (b) logical and systematic thinking required performance improved, (3) integration of prior knowledge and clinical application, and (4) brainstorming learning strategy. The study supports PBL as a continuing education strategy for mental health nurses, and that systematic analysis and curiosity effectively facilitate the development of critical thinking.

Planning LIS Doctoral Education around a Focused Theme: A Report on the B2A Program

ERIC Educational Resources Information Center

Bennett-Kapusniak, Renee; McCleer, Adriana; Glover, Jeannette; Thiele, Jennifer; Wolfram, Dietmar

2016-01-01

This report discusses the Overcoming Barriers to Information Access (B2A) program. This is a doctoral cohort program at the University of Wisconsin-Milwaukee funded by the Institute for Museum and Library Services. The program has focused on educating the next generation of doctoral graduates in library and information science with an emphasis on…

75 FR 21280 - National Advisory Committee on Institutional Quality and Integrity (NACIQI) Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-23

...)(2) of the Federal Advisory Committee Act, section 114(d)(1)(B) of the Higher Education Opportunity Act, and section 114(d)(1)(B) and (D) of the Higher Education Act, as amended. In all instances... the Higher Education Act of 1965, as amended, and 34 CFR parts 602 and 603. In addition, comments for...

Learning Together: A Study of Six B.A. Completion Cohort Programs in Early Care and Education. Year 2 Report. Research Report

ERIC Educational Resources Information Center

Whitebook, Marcy; Sakai, Laura; Kipnis, Fran; Bellm, Dan; Almaraz, Mirella

2010-01-01

Interest in expanding access to higher education has been driven by concerns about ethnic and linguistic stratification within the early childhood workforce, and building a pipeline for diversifying the early care and education (ECE) field's leadership. "Cohort" B.A. completion programs, which target small groups of adults working in ECE…

25 CFR 42.2 - What rights do individual students have?

Code of Federal Regulations, 2010 CFR

2010-04-01

... accorded, at least the following rights: (a) The right to an education that may take into consideration Native American or Alaska Native values; (b) The right to an education that incorporates applicable....2 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION STUDENT RIGHTS § 42.2 What...

Twelve years of IUE spectra of the interacting binary VV Cephei

NASA Technical Reports Server (NTRS)

Bauer, W. H.; Stencel, R. E.; Neff, D. H.

1991-01-01

All well-exposed high-resolution IUE spectra obtained of the eclipsing binary system VV Cephei (M2Iabep + B) are examined. High-temperature absorption features attributable to the hot companion were detected, indicating that the companion (or the inner regions of its accretion disk) are not as hot as a B1-B2 star. Doubling of Fe II (UV 1) lines, with an additional narrow component redshifted by about 60 km/sec, occurs only when the B star is behind the plane of the sky containing the M supergiant, suggesting the existence of mass transfer from the red to the blue star. Absorption features from neutral elements weaken dramatically during egress, while those from ionized elements remain at nearly constant strength. During egress from primary eclipse, the Mg II resonance doublet shows asymmetric double-peaked emission indicative of formation in an expanding chromosphere. It is concluded that the outer atmosphere of the M supergiant is highly clumped.

Hints for new sources of flavour violation in meson mixing

NASA Astrophysics Data System (ADS)

Blanke, M.

2017-07-01

The recent results by the Fermilab-Lattice and MILC collaborations on the hadronic matrix elements entering B_{d,s} - bar{B}_{d,s} mixing show a significant tension of the measured values of the mass differences Δ M_{d,s} with their SM predictions. We review the implications of these results in the context of Constrained Minimal Flavour Violation models. In these models, the CKM elements γ and \\vert V_{ub}\\vert/\\vert V_{cb}\\vert can be determined from B_{d,s} - bar{B}_{d,s} mixing observables, yielding a prediction for γ below its tree-level value. Determining subsequently \\vert V_{cb}\\vert from the measured value of either Δ M_s or ɛ_K gives inconsistent results, with the tension being smallest in the Standard Model limit. This tension can be resolved if the flavour universality of new contributions to Δ F = 2 observables is broken. We briefly discuss the case of U(2)^3 flavour models as an illustrative example.

Len Barton, Inclusion and Critical Disability Studies: Theorising Disabled Childhoods

ERIC Educational Resources Information Center

Goodley, Dan; Runswick-Cole, Katherine

2010-01-01

Len Barton has pioneered the sociological study of education in the areas of disability studies and inclusive education. This paper addresses an argument developed by Len Barton that social exclusion, of which disablism is one element, (1) has many compounding forms of differing exclusions, (2) is not a natural but a socially constructed process,…

Notes on the Redesign of Teacher Education. Teachers for the Future: What Do We Want?

ERIC Educational Resources Information Center

Hawley, Willis D.

These notes offer an overview of the elements that must be considered in designing an effective teacher education program. Each of the following is discussed: (1) the characteristics of an effective career teacher; (2) professional knowledge capabilities and skills often identified as topics that should be included in the teacher education…

Molecular identification and transcriptional regulation of porcine IFIT2 gene.

PubMed

Yang, Xiuqin; Jing, Xiaoyan; Song, Yanfang; Zhang, Caixia; Liu, Di

2018-04-06

IFN-induced protein with tetratricopeptide repeats 2 (IFIT2) plays important roles in host defense against viral infection as revealed by studies in humans and mice. However, little is known on porcine IFIT2 (pIFIT2). Here, we performed molecular cloning, expression profile, and transcriptional regulation analysis of pIFIT2. pIFIT2 gene, located on chromosome 14, is composed of two exons and have a complete coding sequence of 1407 bp. The encoded polypeptide, 468 aa in length, has three tetratricopeptide repeat motifs. pIFIT2 gene was unevenly distributed in all eleven tissues studied with the most abundance in spleen. Poly(I:C) treatment notably strongly upregulated the mRNA level and promoter activity of pIFIT2 gene. Upstream sequence of 1759 bp from the start codon which was assigned +1 here has promoter activity, and deltaEF1 acts as transcription repressor through binding to sequences at position - 1774 to - 1764. Minimal promoter region exists within nucleotide position - 162 and - 126. Two adjacent interferon-stimulated response elements (ISREs) and two nuclear factor (NF)-κB binding sites were identified within position - 310 and - 126. The ISRE elements act alone and in synergy with the one closer to start codon having more strength, so do the NF-κB binding sites. Synergistic effect was also found between the ISRE and NF-κB binding sites. Additionally, a third ISRE element was identified within position - 1661 to - 1579. These findings will contribute to clarifying the antiviral effect and underlying mechanisms of pIFIT2.

Atomic Structure and Valence: Level II, Unit 10, Lesson 1; Chemical Bonding: Lesson 2; The Table of Elements: Lesson 3; Electrolysis: Lesson 4. Advanced General Education Program. A High School Self-Study Program.

ERIC Educational Resources Information Center

Manpower Administration (DOL), Washington, DC. Job Corps.

This self-study program for high-school level contains lessons on: Atomic Structure and Valence, Chemical Bonding, The Table of Elements, and Electrolysis. Each of the lessons concludes with a Mastery Test to be completed by the student. (DB)

The Essence of Powerful Teaching

ERIC Educational Resources Information Center

Brookfield, Stephen

2013-01-01

Empowering learners and using powerful techniques are prominent elements in the discourse of adult and vocational education. But what constitutes the elements of what might be considered as powerful teaching? This paper begins by examining the way educators talk about power and then proposes four elements that lie at the heart of powerful…

A Review of Communication Elements and Learner Support Services in Turkish Distance Education System

ERIC Educational Resources Information Center

Usun, Salih

2003-01-01

The aim of this study is to review the Turkish distance education system, Open Education Faculty (OEF), from the point of view of the communication' elements and learner support services. The study, firstly, introduces the related literature and the growth of distance education in Turkey; explains generally the communication and interaction…

Concentration and distribution of sixty-one elements in coals from DPR Korea

USGS Publications Warehouse

Hu, Jiawen; Zheng, B.; Finkelman, R.B.; Wang, B.; Wang, M.; Li, S.; Wu, D.

2006-01-01

Fifty coal samples (28 anthracite and 22 lignites) were collected from both main and small coal mines in DPR Korea prioritized by resource distribution and coal production. The concentrations of 61 elements in 50 coal samples were determined by several multielement and element-specific techniques, including inductively coupled plasma atomic emission spectrometry (ICP-AES), and inductively coupled plasma mass spectrometry (ICP-MS), ion chromatogram (IC), cold-vapor atomic absorption spectrometry (CV-AAS), and hydride generation atomic absorption spectrometry (HGAAS). The ranges, arithmetic means and geometric means of concentrations of these elements are presented. A comparison with crustal abundances (Clarke values) shows that some potentially hazardous elements in the coals of DPR Korea are highly enriched Li, B, S, Cl, Zn, As, Se, Cd, Sn, Sb, W, Te, Hg, Ag, Pb, and La, Ce, Dy, Tm, Ge, Mo, Cs, Tl, Bi, Th and U are moderately enriched. A comparison of ranges and means of elemental concentrations in DPR Korea, Chinese, and world coals shows the ranges of most elements in DPR Korea coals are very close to the ranges of world coals. Arithmetic means of most elements in DPR Korea coals are close to that of American coals. Most elements arithmetic means are higher in Jurassic and Paleogene coals than coals of other ages. In DPR Korea coals, only seven elements in early Permian coals are higher than other periods: Li, Zn, Se, Cd, Hg, Pb, and Bi. Only five elements B, As, Sr, Mo, W in Neogene coals have arithmetic means higher than others. SiO2 and Al2O 3 in ashes are more than 70% except six samples. The correlation between ash yields and major elements from high to low is in the order of Si>Al>Ti>K>Mg>Fe>Na>Ca>P>S. Most elements have high positive correlation with ash (r>0.5) and show high inorganic affinity. ?? 2005 Elsevier Ltd. All rights reserved.

[Analysis of mineral elements of sunflower (Helianthus annuus L.) grown on saline land in Hetao Irrigation District by ICP-AES].

PubMed

Tong, Wen-Jie; Chen, Fu; Wen, Xin-Ya

2014-01-01

The absorption and accumulation of ten mineral elements in four kinds of organs (root, steam, leaf and flower disc) in Helianthus annuus L. plants cultured in Hetao Irrigation District under different level of salinity stress were determined by ICP-AES with wet digestion (HNO3 + HClO4). The results showed that: (1) The contents of Fe, Mn, Zn, Ca, and Na were highest in roots, so was K in stems, B and Mg in leaves and P in flower discs, while no significant difference was detected in the content of Cu among these organs; (2) The cumulants of Ca, Mg, P, Cu, B and Zn were highest in flower discs, so were Na, Fe and Mn in roots and K in stems; (3) In sunflower plants, the proportion of mineral element cumulant for K : Ca : Mg : P : Na was 16.71 : 5.23 : 3.86 : 1.23 : 1.00, and for Zn : Fe : B : Mn: Cu was 56.28 : 27.75 : 1.93 : 1.17 : 1.00, respectively; (4) The effect of salinity stress on absorption of mineral elements differed according to the kind of organ and element, root was the most sensitive to soil salt content, followed by stem and leaf, and the effect on flower disc seemed complex.

Influence Of Coal Combustion Flue Gas Desulfurization Waste On Element Uptake By Maize (Zea Mays L.)

DOE Office of Scientific and Technical Information (OSTI.GOV)

ANNA, KNOX

2005-01-10

A greenhouse study was conducted to determine the effect of coal combustion flue gas desulfurization (FGD) waste from a coal combustion electric power facility on element uptake by maize (Zea mays L.). Unweathered FGD was applied to an Orangeburg Series (Typic Paleudult) soil with an initial soil pH salt of 4.90. The FGD was added at 0, 1, 2, 4, 6, 8, and 10 per cent by weight. The test plant, maize, was harvested after 6 weeks of growth. Within 56 days of the FGD application, all rates of FGD significantly increased pH in the soil and the soil leachatemore » above 6.0. The elemental concentration of the maize tissues indicated a characteristic elevation of B, Se, Mo, and As. However, no visual symptoms of toxicity of B or other elements in plants were observed. Increasing level of FGD caused a steady decline in dry weight, with the highest treatment producing plants which had approximately half the biomass of the control plants. Due to elevated concentrations of B and other elements and due to adverse yield effects measured on plants, unweathered FGD would not be a suitable amendment for 6-week old maize on this soil.« less

Re-evaluation and extension of the scope of elements in US Geological Survey Standard Reference Water Samples

USGS Publications Warehouse

Peart, D.B.; Antweiler, Ronald C.; Taylor, Howard E.; Roth, D.A.; Brinton, T.I.

1998-01-01

More than 100 US Geological Survey (USGS) Standard Reference Water Samples (SRWSs) were analyzed for numerous trace constituents, including Al, As, B, Ba, Be, Bi, Br, Cd, Cr, Co, Cu, I, Fe, Pb, Li, Mn, Mo, Ni, Rb, Sb, Se, Sr, Te, Tl, U, V, Zn and major elements (Ca, Mg, Na, SiO2, SO4, Cl) by inductively coupled plasma mass spectrometry and inductively coupled plasma atomic emission spectrometry. In addition, 15 USGS SRWSs and National Institute of Standards and Technology (NIST) standard reference material (SRM) 1641b were analyzed for mercury using cold vapor atomic fluorescence spectrometry. Also USGS SRWS Hg-7 was analyzed using isotope dilution-inductively coupled plasma mass spectrometry. The results were compared with the reported certified values of the following standard reference materials: NIST SRM 1643a, 1643b, 1643c and 1643d and National Research Council of Canada Riverine Water Reference Materials for Trace Metals SLRS-1, SLRS-2 and SLRS-3. New concentration values for trace and major elements in the SRWSs, traceable to the certified standards, are reported. Additional concentration values are reported for elements that were neither previously published for the SRWSs nor traceable to the certified reference materials. Robust statistical procedures were used that were insensitive to outliers. These data can be used for quality assurance/quality control purposes in analytical laboratories.

Frequency-Response Identification of XV-15 Tilt-Rotor Aircraft Dynamics.

DTIC Science & Technology

1987-05-01

and the rotor interference with the other 2 aircraft elements are modeled in detail. Also modeled are numerous sub- system dynamics such as the engine ...scope and quality, as a dissertation for the degree of Doctor of Philosophy. (Electrical Engineering ) Approved for the University Com ittee on Graduate...Spectral Relationships .................................. 143 B.2 Numerical Study......................................... 149 B.3 Conclusions of

International Conference on Harmonisation; Electronic Transmission of Postmarket Individual Case Safety Reports for Drugs and Biologics, Excluding Vaccines; Availability of Food and Drug Administration Regional Implementation Specifications for ICH E2B(R3) Reporting to the Food and Drug Administration Adverse Event Reporting System. Notice of Availability.

PubMed

2016-06-23

The Food and Drug Administration (FDA) is announcing the availability of its FDA Adverse Event Reporting System (FAERS) Regional Implementation Specifications for the International Conference on Harmonisation (ICH) E2B(R3) Specification. FDA is making this technical specifications document available to assist interested parties in electronically submitting individual case safety reports (ICSRs) (and ICSR attachments) to the Center for Drug Evaluation and Research (CDER) and the Center for Biologics Evaluation and Research (CBER). This document, entitled "FDA Regional Implementation Specifications for ICH E2B(R3) Implementation: Postmarket Submission of Individual Case Safety Reports (ICSRs) for Drugs and Biologics, Excluding Vaccines" supplements the "E2B(R3) Electronic Transmission of Individual Case Safety Reports (ICSRs) Implementation Guide--Data Elements and Message Specification" final guidance for industry and describes FDA's technical approach for receiving ICSRs, for incorporating regionally controlled terminology, and for adding region-specific data elements when reporting to FAERS.

Dysprosium-free melt-spun permanent magnets.

PubMed

Brown, D N; Wu, Z; He, F; Miller, D J; Herchenroeder, J W

2014-02-12

Melt-spun NdFeB powders can be formed into a number of different types of permanent magnet for a variety of applications in electronics, automotive and clean technology industries. The melt-spinning process produces flake powder with a fine uniform array of nanoscale Nd2Fe14B grains. These powders can be net-shape formed into isotropic polymer-bonded magnets or hot formed into fully dense magnets. This paper discusses the influence of heavy rare earth elements and microstructure on the magnetic performance, thermal stability and material cost of NdFeB magnets. Evidence indicates that melt-spun nanocrystalline NdFeB magnets are less dependent on heavy rare earth elements for high-temperature performance than the alternative coarser-grained sintered NdFeB magnets. In particular, hot-pressed melt-spun magnets are an attractive low-cost solution for applications that require thermal stability up to 175-200 °C.

Investigations on the direct introduction of cigarette smoke for trace elements analysis by inductively coupled plasma mass spectrometry

NASA Astrophysics Data System (ADS)

Chang, Michael J.; Naworal, John D.; Walker, Kathleen; Connell, Chris T.

2003-11-01

Direct introduction of mainstream cigarette smoke into an inductively coupled plasma mass spectrometry (ICP-MS) has been investigated with respect to its feasibility for on-line analysis of trace elements. An automated apparatus was designed and built interfacing a smoking machine with an ICP-MS for smoke generation, collection, injection and analysis. Major and minor elements present in the particulate phase and the gas phase of mainstream cigarette smoke of 2R4F reference cigarettes have been qualitatively identified by examination of their full mass spectra. This method provides a rapid-screening analysis of the transfer of trace elements into mainstream smoke during cigarette combustion. A full suite of elements present in the whole cigarette smoke has been identified, including As, B, Ba, Br, Cd, Cl, Cs, Cu, Hg, I, K, Li, Mn, Na, Pb, Rb, Sb, Sn, Tl and Zn. Of these elements, the major portions of B, Ba, Cs, Cu, K, Li, Mn, Na, Pb, Rb, Sn, Tl and Zn are present in the particulate phase, whereas the major portion of Hg is present in the gas phase. As, Br, Cd, Cl, I and Sb exist in a distribution between the gas phase and the particulate phase. Depending on the element, the precision of measurement ranges from 5 to 25% in terms of relative standard deviation of peak height and peak area, based on the fourth puff of 2R4F mainstream cigarette smoke analyzed in five smoking replicates.

An Experimental Investigation of Effects of Fluxes (Na3AlF6 and K2TiF6), Element Alloys (Mg), and Composite Powders ((Al + TiC)CP and (Al + B4C)CP) on Distribution of Particles and Phases in Al-B4C and Al-TiC Composites

NASA Astrophysics Data System (ADS)

Mazaheri, Younes; Emadi, Rahmatollah; Meratian, Mahmood; Zarchi, Mehdi Karimi

2017-04-01

The wettability, incorporation, and gravity segregation of TiC and B4C particles into molten aluminum are important problems in the production of Al-TiC and Al-B4C composites by the casting techniques. In order to solve these problems, different methods consisting of adding the Na3AlF6 and K2TiF6 fluxes and Mg (as the alloying element) into the molten aluminum and injection of the (Al + TiC)CP and (Al + B4C)CP composite powders instead of B4C and TiC particles are evaluated. In this work, the conditions of sample preparation, such as particle addition temperature, stirring speed, and stirring time, are determined after many studies and tests. Microstructural characterizations of samples are investigated by scanning electron microscopy equipped with energy dispersive spectroscopy (EDS) and X-ray diffractometry. The results show better distribution and incorporation of TiCp and B4Cp in aluminum matrix when the fluxes are used, as well as EDS analysis of the interface between the matrix and reinforcement-strengthened formation of the different phases such as Al4C3 in the Al-TiC composites and Al3BC, TiB2 in the Al-B4C composites.

Raman Spectroscopic Study of Molecular Orientation in Vitreous B2O3 Films.

DTIC Science & Technology

1981-07-10

upQ, and the squares of its elements, which are proportional to the experi- mental Razman intensities, are elements of the tensor a 2,where:Si j k 2...California 94720 Mr . Robert W. Jones Advanced Projects anager Dr. Turis W. Frank Hughes Aircraft Company De t. ,nt ’f Chemical Engineering Mail...Dr. George Sandoz Attn: Mr . Joe McCartney 536 S. Clark Street San Diego, California 92152 Chicago, Illinois 60605 1 Naval Weapons Center ONR Area

Synthesis and structural characterisation of a novel phosphine-borane-stabilised dicarbanion and an unusual bis(phosphine-borane).

PubMed

Izod, Keith; McFarlane, William; Tyson, Brent V; Clegg, William; Harrington, Ross W

2004-03-07

The reaction between the phosphine-borane-substituted alkene [Pr(n)(2)P(BH(3))](Me(3)Si)C[double bond]CH(2) and elemental lithium in THF yields the complex [(pmdeta)Li[Pr(n)(2)P(BH(3))](Me(3)Si)CCH(2)](2)(2b) after recrystallisation; an X-ray crystallographic study of 2b reveals that the lithium is bound to the BH(3) hydrogens of the ligand, with no Li-C(carbanion) contact.

Confirmatory Survey Report for Area B1S/B2S at the Chevron Mining Washington Remediation Project, Washington, PA

DOE Office of Scientific and Technical Information (OSTI.GOV)

W. C. Adams

2007-11-20

During the period of October 2 and 3, 2007, the Oak Ridge Institute for Science and Education (ORISE) performed confirmatory radiological survey activities which included gamma surface scans within Area B1S/B2S and the collection of soil samples from these areas.

MPEG-4 AVC saliency map computation

NASA Astrophysics Data System (ADS)

Ammar, M.; Mitrea, M.; Hasnaoui, M.

2014-02-01

A saliency map provides information about the regions inside some visual content (image, video, ...) at which a human observer will spontaneously look at. For saliency maps computation, current research studies consider the uncompressed (pixel) representation of the visual content and extract various types of information (intensity, color, orientation, motion energy) which are then fusioned. This paper goes one step further and computes the saliency map directly from the MPEG-4 AVC stream syntax elements with minimal decoding operations. In this respect, an a-priori in-depth study on the MPEG-4 AVC syntax elements is first carried out so as to identify the entities appealing the visual attention. Secondly, the MPEG-4 AVC reference software is completed with software tools allowing the parsing of these elements and their subsequent usage in objective benchmarking experiments. This way, it is demonstrated that an MPEG-4 saliency map can be given by a combination of static saliency and motion maps. This saliency map is experimentally validated under a robust watermarking framework. When included in an m-QIM (multiple symbols Quantization Index Modulation) insertion method, PSNR average gains of 2.43 dB, 2.15dB, and 2.37 dB are obtained for data payload of 10, 20 and 30 watermarked blocks per I frame, i.e. about 30, 60, and 90 bits/second, respectively. These quantitative results are obtained out of processing 2 hours of heterogeneous video content.

A Crossover from High Stiffness to High Hardness: The Case of Osmium and Its Borides

NASA Astrophysics Data System (ADS)

Bian, Yongming; Liu, Xiaomei; Li, Anhu; Liang, Yongcheng

2016-09-01

Transition-metal light-element compounds are currently raising great expectations for hard and superhard materials. Using the widely attracting osmium (Os) and its borides (OsB, Os2B3 and OsB2) as prototypes, we demonstrate by first-principles calculations that heavy transition metals, which possess high stiffness but low hardness, can be converted into highly hard materials by incorporating of light elements to form compounds. Such a crossover is a manifestation that the underlying sources of high stiffness and high hardness are fundamentally different. The stiffness is related to elastic deformation that is closely associated with valence electron density, whereas the hardness depends strongly on plastic deformation that is determined by bonding nature. Therefore, the incorporation of light atoms into transition metal should be a valid pathway of designing hard and superhard materials. This strategy is in principle also applicable to other transition-metal borides, carbides, and nitrides.

Destabilization of B2 RNA by EZH2 activates the stress response

PubMed Central

Zovoilis, Athanasios; Cifuentes-Rojas, Catherine; Chu, Hsueh-Ping; Hernandez, Alfredo J.; Lee, Jeannie T.

2017-01-01

SUMMARY More than 98% of the mammalian genome is noncoding and interspersed transposable elements account for ~50% of noncoding space. Here, we demonstrate that a specific interaction between the Polycomb protein, EZH2, and RNA made from B2 SINE retrotransposons controls stress-responsive genes in mouse cells. In the heat shock model, B2 RNA binds stress genes and suppresses their transcription. Upon stress, EZH2 is recruited and triggers cleavage of B2 RNA. B2 degradation in turn upregulates stress genes. Evidence indicates that B2 RNA operates as “speed bump” against advancement of RNA Polymerase II, and temperature stress releases the brakes on transcriptional elongation. These data attribute a new function to EZH2 that is independent of its histone methyltransferase activity and reconcile how EZH2 can be associated with both gene repression and activation. Our study reveals that EZH2 and B2 together control activation of a large network of genes involved in thermal stress. PMID:27984727

Analysis with electron microscope of multielement samples using pure element standards

DOEpatents

King, W.E.

1986-01-06

This disclosure describes a method and modified analytical electron microscope for determining the concentration of elements in a multielement sample by exposing samples with differing thicknesses for each element to a beam of electrons. Simultaneously the electron dosage and x-ray intensities are measured for each sample of element to determine a ''K/sub AB/'' value to be used in the equation (I/sub A/I/sub B/) = K/sub AB/ (C/sub A//C/sub B/), where I is intensity and C is concentration for elements A and B. The multielement sample is exposed to determine the concentrations of the elements in the sample.

Study of the chemical elements and polycyclic aromatic hydrocarbons in atmospheric particles of PM 10 and PM 2.5 in the urban and rural areas of South Brazil

NASA Astrophysics Data System (ADS)

Dallarosa, Juliana; Calesso Teixeira, Elba; Meira, Lindolfo; Wiegand, Flavio

2008-07-01

The purpose of this work is to study the chemical elements and PAHs associated with atmospheric particulate in samples of PM 10 collected in the Metropolitan Area of Porto Alegre—MAPA, Rio Grande do Sul, Brazil. In addition, to study the chemical elements associated with particles of different fractions of PM 10-2.5 and PM 2.5 using dichotomous sampling, in urban (MAPA) and rural areas. Two types of samplers were used: HV PM 10 and Dichotomous (PM 10-2.5 and PM 2.5). Samples were collected during 2002 and 2005. The concentration of the elements Si, S, Cl, K, Ca, Ti, V, Cr, Mn, Fe, Ni, Cu, and Zn was determined by PIXE (Particle-Induced X-ray Emission), while the concentrations of 16 major PAHs were determined according to EPA with a gas chromatograph coupled to a mass spectrometer (GS/MS). Results showed that elements of anthropogenic origin (V, Zn, Cr, Ni, Cu, and S) were mainly associated with the fraction PM 2.5, while the soil dust (Si, Al, Ti and Fe) were found mainly on fraction PM 10-2.5. In samples of PM 10, the most frequent PAHs found were Bgp, Flt, BaA, Chr, B(b + k)F, BaP and Dba. The types of emission and their association with the atmospheric parameters were studied applying the statistical analysis of the principal component method. The main sources found in the area under study were vehicles, industries (steel mills and a coal-fired power station), dust, sea breeze, and burning.

Revisiting Grodzins systematics of B(E2) values

DOE PAGES

Pritychenko, B.; Birch, M.; Singh, B.

2017-04-03

Using Grodzins formalism, we analyze systematics of our latest evaluated B(E2) data for all the even–even nuclei in Z=2–104. The analysis indicates a low predictive power of systematics for a large number of cases, and a strong correlation between B(E2) fit values and nuclear structure effects. These findings provide a strong rationale for introduction of individual or elemental (grouped by Z) fit parameters. The current estimates of quadrupole collectivities for systematics of even–even nuclei yield complementary values for comparison with experimental results and theoretical calculations. Furthermore, the lists of fit parameters and predicted B(E2) values are given and possible implicationsmore » are discussed.« less

Transition Metal Complexes of Quinolino[3,2-b]benzodiazepine and Quinolino[3,2-b]benzoxazepine: Synthesis, Characterization, and Antimicrobial Studies

PubMed Central

Basavaraju, B.; Bhojya Naik, Halehatty S.; Prabhakara, Mustur C.

2007-01-01

The synthesis and characterization of title complexes of the ligand Quinolino[3,2-b]benzodiazepine (QBD) and Quinolino[3,2-b]benzoxazepine (QBO) are reported. The complexes have been characterized by elemental analysis, molar conductance, magnetic studies, IR, H1 NMR, and UV-visible studies. They have the stoichiometry [ML2C12], where M=Co(II)/Ni(II), L=QBD/QBO, and [MLC12], where M=Zn(II)/Cd(II), L=QBD/QBO. The antibacterial and antifungal activity of the metal complexes has been investigated. The complexes were found to have higher antimicrobial activity than the parent ligand. PMID:18273383

Possible Detection of Solar Neutrons from the ISS

NASA Astrophysics Data System (ADS)

Benker, Nicole; Echeverria-Mora, Elena; Hamblin, Jennifer; Dowben, Peter A.; Enders, Axel; Kananen, Brant; Petrosky, James; McClory, John

2018-06-01

A low energy steady state solar neutron flux has been long predicted [1]. The Detector for the Analysis of Solar Neutrons (DANSON), designed to detect this flux, was launched on the OA-5 mission to the International Space Station (ISS) on 17 Oct. 2016, deployed aboard ISS, and returned 19 March 2017. This detector is insensitive to high energy solar neutron events associated with solar flares, which have now been routinely detected in the range of 40 to 140 MeV, but the lower energy steady state solar neutron background has not been thoroughly examined. DANSON is based on boron rich detector elements combined with a plastic moderator to thermalize neutrons at energies above 40 meV, maximizing the B10 capture of epithermal neutrons. The detector elements include boron carbide (B10C2HX) heterojunction diodes on silicon and lithium tetraborate (Li2B4O7) single crystals. Three types of lithium tetraborate detector elements are used: crystals with a natural abundance of 10B (approx. 20% 10B, 80% 11B), crystals enriched in 10B, and crystals enriched in 11B. Enrichment in 10B provides a higher cross section for thermal neutron capture, while enrichment in 11B results in a negligible cross section for thermal neutron capture while maintaining a proton capture cross section comparable to that of 10B. The signature of neutron capture in the lithium tetraborate samples is evident in the thermoluminescent spectra. In the boron carbide diodes, the signature is measured in the huge decrease in drift carrier lifetimes compared to pre-flight characterization data, corresponding to about 3×109 neutrons/cm2 exposure. Since the estimated total solar exposure time for deployment is 8×106 seconds, this amounts to about 250 to 375 neutrons and protons/cm2sec. The detector package shows increased detection on the zenith side of ISS, after subtraction of radiation events from energetic protons and other sources, indicating possible detection of solar neutrons. Additionally, detection of events on the nadir side implies detection of cosmic ray generated neutrons.[1] Biermann VL, Haxe O, Schulter A (1951) Neutrale Ultrastrahlung von der Sonne. Zeitschrift für Naturforschung 6a: 47-48.

Defining Stability, Security, Transition, and Reconstruction (SSTR) Operations Requirements for Future Department of the Navy Training and Analytical Models and Simulations

DTIC Science & Technology

2008-09-01

43 B. WELL-DEFINED MEASURES ........................................................... 43 C. ESSENTIAL ELEMENTS OF ANALYSIS ( EEA ...45 D. EEA PROCESS FOR RESTORATION OF ESSENTIAL SERVICE - WATER...FBCB2 Force XXI Battle Command, Brigade-and-Below FM Army Field Manual EEA Essential Elements of Analysis EPG Electronic Proving Ground ESS

The Benefits of Nuclear Thermal Propulsion (NTP) in an Evolvable Mars Campaign

NASA Technical Reports Server (NTRS)

Borowski, Stanley K.; Mccurdy, David R.

2014-01-01

NTR: High thrust high specific impulse (2 x LOXLH2chemical) engine uses high power density fission reactor with enriched uranium fuel as thermal power source. Reactor heat is removed using H2propellant which is then exhausted to produce thrust. Conventional chemical engine LH2tanks, turbopumps, regenerative nozzles and radiation-cooled shirt extensions used --NTR is next evolutionary step in high performance liquid rocket engines During the Rover program, a common fuel element tie tube design was developed and used in the design of the 50 klbf Kiwi-B4E (1964), 75 klbf Phoebus-1B (1967), 250 klbf Phoebus-2A (June 1968), then back down to the 25 klbf Pewee engine (Nov-Dec 1968) NASA and DOE are using this same approach: design, build, ground then flight test a small engine using a common fuel element that is scalable to a larger 25 klbf thrust engine needed for human missions

Bioavailability of potentially toxic elements in soil-grapevine (leaf, skin, pulp and seed) system and environmental and health risk assessment.

PubMed

Milićević, Tijana; Urošević, Mira Aničić; Relić, Dubravka; Vuković, Gordana; Škrivanj, Sandra; Popović, Aleksandar

2018-06-01

Monitoring of potentially toxic elements in agricultural soil represents the first measure of caution regarding food safety, while research into element bioavailability should be a step forward in understanding the element transportation chain. This study was conducted in the grapevine growing area ("Oplenac Wine Route") for investigating element bioavailability in the soil-grapevine system accompanied by an assessment of the ecological implications and human health risk. Single extraction procedures (CH 3 COOH, Na 2 EDTA, CaCl 2 , NH 4 NO 3 and deionised H 2 O) and digestion were performed to estimate the bioavailability of 22 elements (Al, As, B, Ba, Be, Ca, Cd, Co, Cr, Cu, Fe, K, Li, Mg, Mn, Na, Ni, Pb, Sb, Sr, V and Zn) from the topsoil (0-30 cm) and subsoil (30-60 cm) to the grapevine parts (leaf, skin, pulp and seed) and wine. The extractants were effective comparing to the pseudo-total concentrations in following order Na 2 EDTA ˃ CH 3 COOH ˃ NH 4 NO 3  ˃ CaCl 2 , H 2 O 2 h and 16 h. The most suitable extractants for assessing the bioavailability of the elements from the soil to the grapevine parts were CaCl 2 , NH 4 NO 3 and Na 2 EDTA, but deionised H 2 O could be suitable, as well. The results showed that Ba was the most bioavailable element in the soil-grapevine system. Contamination factor implied a moderate contamination (1 < CF < 3) of the soil. The concentrations of Cr, Ni and Cd in the soil were above the maximum allowed concentrations. According to the biological accumulation coefficient (BAC), the grape seeds and grapevine leaves mostly accumulated Cu and Zn from the soil, respectively. Based on ratio factor (RF > 1), the influence of atmospheric deposition on the aerial grapevine parts (leaves and grape skin) was observed. Nevertheless, low adverse health risk effects (HI < 1 and R ≤ 1 × 10 -6 ) were estimated for farmers and grape and wine consumers. Copyright © 2018 Elsevier B.V. All rights reserved.

Decisions and the Environmental-Adventure Model.

ERIC Educational Resources Information Center

Lindenmeier, Donna K.

Historically, outdoor recreation/education (ORE) has been associated with environmental recreation/education, but in the past few decades has become increasingly associated with adventure education/recreation. Many outdoor programs have attempted to combine the two elements; others question the combination of the two elements in a single program.…

Influences of health literacy, judgment skills, and empowerment on asthma self-management practices.

PubMed

Londoño, Ana Maria Moreno; Schulz, Peter J

2015-07-01

Asthma self-management has been recognized as an essential factor for the improvement of asthma outcomes and patients' quality of life (WHO, 2013). Likewise, empowerment and health literacy have been noted as important elements for the management of chronic diseases. To study the influence of health literacy and empowerment on asthma self-management. This cross-sectional study used a self-reported questionnaire assessing health literacy, judgment skills, empowerment, and asthma self-management; 236 patients were recruited from medical offices in Switzerland and Italy. Judgment skills (B=2.28, p<0.001) and empowerment (B=0.19, p<0.05) have a significant and positive influence on several asthma self-management practices such as use of medicines, timely medical consultation, and asthma triggers control whereas health literacy (B=-0.15, p<0.175) appeared to have a negative effect on self-management practices. However, this was not significant. These findings suggest that empowered patients with adequate judgment skills carry out key self-management tasks more appropriately, which in turn will potentially result in better asthma control. This study recommends that both empowerment and judgment skills should be addressed in patient education as they serve as essential motivators to engage patients in these behaviors. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Proceedings of the Annual RAND-China Reform Forum Conference (6th) Held in Santa Monica, California on August 28-29, 2003

DTIC Science & Technology

2005-01-01

documents for commercial use. Limited Electronic Distribution Rights For More Information CHILD POLICY CIVIL JUSTICE EDUCATION ENERGY AND ENVIRONMENT HEALTH...Reform Forum Conference. August 28-29, 2003 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK...have been reviewed and approved by RAND Science and Technology. Proceedings of the 6th Annual RAND–China Reform Forum Conference August 28–29

Flavonoids exhibit diverse effects on CYP11B1 expression and cortisol synthesis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cheng, Li-Chuan; Li, Lih-Ann, E-mail: lihann@nhri.org.tw

2012-02-01

CYP11B1 catalyzes the final step of cortisol biosynthesis. The effects of flavonoids on transcriptional expression and enzyme activity of CYP11B1 were investigated using the human adrenocortical H295R cell model. All tested nonhydroxylated flavones including 3′,4′-dimethoxyflavone, α-naphthoflavone, and β-naphthoflavone upregulated CYP11B1 expression and cortisol production, whereas apigenin and quercetin exhibited potent cytotoxicity and CYP11B1 repression at high concentrations. Nonhydroxylated flavones stimulated CYP11B1-catalyzed cortisol formation at transcriptional level. Resveratrol increased endogenous and substrate-supported cortisol production like nonhydroxylated flavones tested, but it had no effect on CYP11B1 gene expression and enzyme activity. Resveratrol appeared to alter cortisol biosynthesis at an earlier step. Themore » Ad5 element situated in the − 121/− 106 region was required for basal and flavone-induced CYP11B1 expression. Overexpression of COUP-TFI did not improve the responsiveness of Ad5 to nonhydroxylated flavones. Although COUP-TFI overexpression increased CYP11B1 and CYP11B2 promoter activation, its effect was not mediated through the common Ad5 element. Treating cells with PD98059 (a flavone-type MEK1 inhibitor) increased CYP11B1 promoter activity, but not involving ERK signaling because phosphorylation of ERK1/2 remained unvarying throughout the course of treatment. Likewise, AhR was not responsible for the CYP11B1-modulating effects of flavonoids because inconsistency with their effects on AhR activation. 3′,4′-dimethoxyflavone and 8-Br-cAMP additively activated CYP11B1 promoter activity. H-89 reduced 3′,4′-dimethoxyflavone-induced CYP11B1 promoter activation but to a lesser extent as compared to its inhibition on cAMP-induced transactivation. Our data suggest that constant exposure to nonhydroxylated flavones raises a potential risk of high basal and cAMP-induced cortisol synthesis in consequence of increased CYP11B1 expression. -- Highlights: ► Nonhydroxylated flavones stimulate basal cortisol synthesis and CYP11B1 expression. ► The Ad5 element is required for nonhydroxylated flavone-elicited CYP11B1 induction. ► COUP-TFI elevates CYP11B1 and CYP11B2 transactivation but not through Ad5. ► AhR, ERK, and PKA are not involved in nonhydroxylated flavone-mediated regulation. ► Resveratrol affects cortisol biosynthesis at a step earlier than CYP11B1.« less

National Study of Excellence and Innovation in Physical Therapist Education: Part 1-Design, Method, and Results.

PubMed

Jensen, Gail M; Nordstrom, Terrence; Mostrom, Elizabeth; Hack, Laurita M; Gwyer, Janet

2017-09-01

The Carnegie Foundation for the Advancement of Teaching commissioned the Preparation for the Professions Program, a qualitative study of professional education in 5 professions: medicine, nursing, law, engineering, and clergy. These studies identified curricular structures, instructional practices, assessment approaches, and environmental characteristics that support the preparation of professionals and led to educational reforms. The physical therapy profession has not had any in-depth, national investigation of physical therapist education since the Catherine Worthingham studies conducted more than 50 years ago. This research was a Carnegie-type study, investigating elements of excellence and innovation in academic and clinical physical therapist education in the United States. Five physical therapist education researchers from across the United States used a qualitative multiple-case study design. Six academic and 5 clinical programs were selected for the study. The academic institutions and clinical agencies studied were diverse in size, institutional setting, geography, and role in residency education. Qualitative case studies were generated from review of artifacts, field observations, and interviews (individual and focus group), and they provided the data for the study. A conceptual framework grounded in 3 major dimensions was generated, with 8 supporting elements: (1) culture of excellence (shared beliefs and values, leadership and vision, drive for excellence, and partnerships), (2) praxis of learning (signature pedagogy, practice-based learning, creating adaptive learners, and professional formation), and (3) organizational structures and resources. Building on the work of the Carnegie Foundation's Preparation for the Professions Program, a conceptual model was developed, representing the dimensions and elements of excellence in physical therapist education that is centered on the foundational importance of a nexus of linked and highly valued aims of being learner centered and patient centered in all learning environments, both academic and clinical. © 2017 American Physical Therapy Association

A Latent Profile Analysis of Latino Parenting: The Infusion of Cultural Values on Family Conflict.

PubMed

Ayón, Cecilia; Williams, Lela Rankin; Marsiglia, Flavio F; Ayers, Stephanie; Kiehne, Elizabeth

The purpose of the present study was to (a) examine how acculturation and social support inform Latinos' parenting behaviors, controlling for gender and education; (b) describe parenting styles among Latino immigrants while accounting for cultural elements; and (c) test how these parenting styles are associated with family conflict. A 3 step latent profile analysis with the sample ( N = 489) revealed best fit with a 4 profile model ( n = 410) of parenting: family parenting ( n = 268, 65%), child-centered parenting ( n = 68, 17%), moderate parenting ( n = 60, 15%), and disciplinarian parenting ( n = 14, 3%). Parents' gender, acculturation, and social support significantly predicted profile membership. Disciplinarian and moderate parenting were associated with more family conflict. Recommendations include integrating culturally based parenting practices as a critical element to family interventions to minimize conflict and promote positive youth development.

Compact, low-loss and low-power 8×8 broadband silicon optical switch.

PubMed

Chen, Long; Chen, Young-kai

2012-08-13

We demonstrated a 8×8 broadband optical switch on silicon for transverse-electrical polarization using a switch-and-selector architecture. The switch has a footprint of only 8 mm × 8 mm, minimum on-chip loss of about 4 dB, and a port-to-port insertion loss variation of only 0.8 dB near some spectral regions. The port-to-port isolation is above 30 dB over the entire 80-nm-wide spectral range or above 45 dB near the central 30 nm. We also demonstrated a switching power of less than 1.5 mW per element and a speed of 2 kHz, and estimated the upper bound of total power consumption to be less than 70 mW even without optimization of the default state of the individual switch elements.

The effect of test kit provision, and individual and family education on the uptake rates of fecal occult blood test in an Asian population: a randomized controlled trial.

PubMed

Ha, Tam Cam; Yong, Sook Kwin; Yeoh, Kheng-Wei; Kamberakis, Kay; Yeo, Richard Ming Chert; Koh, Gerald Choon-Huat

2014-11-01

The purpose of the study was to investigate whether fecal occult blood test (FOBT) home-delivery and individual education or combined with family education increases FOBT uptake rates in Singapore. This is a randomized controlled intervention study of Singaporean residents aged 50 years and above, conducted in May 2012 till May 2013. Eligible individuals in randomly selected households were screened, and one member was randomly selected and allocated to one of the four arms: Group A (individual and family education, FOBT kits provided), Group B (individual education only, FOBT kits provided), Group C (no education, FOBT kits provided) and Group D (no education or FOBT kits provided). Overall response rate was 74.7 %. The FOBT return rates for groups A, B, C and D were 24.5 % [CI 16.2-34.4 %], 25.3 % [CI 16.4-36.0 %], 10.7 % [CI 4.7-19.9 %] and 2.2 % [CI 0.3-7.7 %], respectively. Respondents who were provided education and home-delivered FOBT kits were 15 times more likely to return FOBT kits [Group A: OR 15.0 (3.4-66.2); Group B: OR 15.5 (3.5-68.8)] and those provided with home-delivered FOBT without education were five times more likely to return FOBT kits [Group C: OR 5.8 (1.2-28.3)] than those without education and FOBT kits (Group D). There was no significant difference in return of FOBT kits whether education was provided to subject with or without a family member. Home delivery of FOBT kits increased FOBT return rates and individual education combined with home-delivered FOBT increased FOBT return rates even further. However, additional combination with family education did not increase FOBT rates further.

Non-stoichiometric AB5 alloys for metal hydride electrodes

DOEpatents

Reilly, James J.; Adzic, Gordana D.; Johnson, John R.; Vogt, Thomas; McBreen, James

2001-01-01

The present invention provides a non-stoichiometric alloy comprising a composition having the formula AB.sub.5+X an atomic ratio wherein A is selected from the group consisting of the rare earth metals, yttrium, mischmetal, or a combination thereof; B is nickel and tin, or nickel and tin and at least a third element selected from the group consisting of the elements in group IVA of the periodic table, aluminum, manganese, iron, cobalt, copper, antimony or a combination thereof; X is greater than 0 and less than or equal to about 2.0; and wherein at least one substituted A site is occupied by at least one of the B elements. An electrode incorporating said alloy and an electrochemical cell incorporating said electrode are also described.

AIDS and HIV Training and Education in Criminal Justice Agencies. AIDS Bulletin.

ERIC Educational Resources Information Center

Hammett, Theodore M.

This bulletin summarizes key elements of an effective AIDS training and education program for law enforcement and corrections personnel. First, these key elements of training and education for criminal justice personnel are discussed: staff participation in materials development; timely and frequent training; mandatory training; live training by…

Universal Design for Learning: Curriculum, Technology, and Accessibility.

ERIC Educational Resources Information Center

Erlandson, Robert F.

This paper examines how teachers, as educational designers, can utilize universal design for learning (UDL) concepts. UDL is a comprehensive approach to the design of educational systems that addresses elements necessary for the achievement of desired educational goals and objectives: elements such as equity among the participants, environmental…

The Higher Education System: Academic Organization in Cross-National Perspective.

ERIC Educational Resources Information Center

Clark, Burton R.

Basic elements of the higher education system are considered, along with variations across nations (the United Kingdom, Sweden, Japan, Italy, France, the Federal Republic of Germany, Australia, Canada, the United States, Poland, Yugoslavia, Mexico, and Thailand). Three basic elements of the organization of higher education system are identified:…

Biomechanical study of four kinds of percutaneous screw fixation in two types of unilateral sacroiliac joint dislocation: a finite element analysis.

PubMed

Zhang, Lihai; Peng, Ye; Du, Chengfei; Tang, Peifu

2014-12-01

To compare the biomechanical stability of four different kinds of percutaneous screw fixation in two types of unilateral sacroiliac joint dislocation. Finite element models of unstable Tile type B and type C pelvic ring injuries were created in this study. Modelling was based on fixation with a single S1 screw (S1-1), single S2 screw (S2-1), two S1 screws (S1-2) and a combination of a single S1 and a single S2 screw (S1–S2). The biomechanical test of two types of pelvic instability (rotational or vertical) with four types of percutaneous fixation were compared. Displacement, flexion and lateral bend (in bilateral stance) were recorded and analyzed. Maximal inferior translation (displacement) was found in the S2-1 group in type B and C dislocations which were 1.58 mm and 1.90 mm, respectively. Maximal flexion was found in the S2-1 group in type B and C dislocations which were 1.55° and 1.95°, respectively. The results show that the flexion from most significant angulation to least is S2-1, S1-1, S1-2, and S1–S2 in type B and C dislocations. All the fixations have minimal lateral bend. Our findings suggest single screw S1 fixation should be adequate fixation for a type B dislocation. For type C dislocations, one might consider a two screw construct (S1–S2) to give added biomechanical stability if clinically indicated.

The GPRIME approach to finite element modeling

NASA Technical Reports Server (NTRS)

Wallace, D. R.; Mckee, J. H.; Hurwitz, M. M.

1983-01-01

GPRIME, an interactive modeling system, runs on the CDC 6000 computers and the DEC VAX 11/780 minicomputer. This system includes three components: (1) GPRIME, a user friendly geometric language and a processor to translate that language into geometric entities, (2) GGEN, an interactive data generator for 2-D models; and (3) SOLIDGEN, a 3-D solid modeling program. Each component has a computer user interface of an extensive command set. All of these programs make use of a comprehensive B-spline mathematics subroutine library, which can be used for a wide variety of interpolation problems and other geometric calculations. Many other user aids, such as automatic saving of the geometric and finite element data bases and hidden line removal, are available. This interactive finite element modeling capability can produce a complete finite element model, producing an output file of grid and element data.

2012-13 Operating Grants: Too Little to Offset District Budget Shortfalls. BCTF Research Report. Section V. 2012-EF-01

ERIC Educational Resources Information Center

White, Margaret

2012-01-01

The BC Ministry of Education announcement about 2012-13 operating grants estimates includes "new" funding to districts of $11.2 million for vulnerable students, $10.7 million for districts to implement elements of the Education Plan, and $21.8 million to address "districts' differing geographic circumstances." This makes for a…

Trends in Environmental Education Images of Textbooks from Western and Eastern European Countries and Non-European Countries

ERIC Educational Resources Information Center

Carvalho, Graca S.; Tracana, Rosa Branca; Skujiene, Grita; Turcinaviciene, Jurga

2011-01-01

Textbook analysis is seen as a major element for studying environmental education addressing pupils, image analysis being rather relevant when studying textbooks written in 11 languages. We analysed 25 textbooks from 14 countries addressed to 14-16-year-old pupils, focusing on: (1) local and foreign/global images; (2) urban/rural and nature…

Answering the Demands of a New Workplace: Using Competency-Based Vocational Education To Prepare Workers. A VES Briefing Paper.

ERIC Educational Resources Information Center

Moore, Debra M.; Pershing, James A.

Common elements of definitions of competency-based vocational education (CBVE) are: (1) CBVE is an instructional process; (2) students must develop competencies; (3) competency includes skill, knowledge, and attitudes; and (4) the outcome is successful job performance. Advantages of CBVE include: (1) students' awareness of what is expected of them…

Aerothermal modeling program. Phase 2, element B: Flow interaction experiment

NASA Technical Reports Server (NTRS)

Nikjooy, M.; Mongia, H. C.; Murthy, S. N. B.; Sullivan, J. P.

1987-01-01

NASA has instituted an extensive effort to improve the design process and data base for the hot section components of gas turbine engines. The purpose of element B is to establish a benchmark quality data set that consists of measurements of the interaction of circular jets with swirling flow. Such flows are typical of those that occur in the primary zone of modern annular combustion liners. Extensive computations of the swirling flows are to be compared with the measurements for the purpose of assessing the accuracy of current physical models used to predict such flows.

Installation Restoration Program. Preliminary Assessment: Records Search for the 119th Fighter Interceptor Group, North Dakota Air National Guard, Hector Field , Fargo, North Dakota.

DTIC Science & Technology

1987-10-01

3𔃿 I, UNLSSflD r/ H : . ,_ .m 0 1 -8 111 . ! m m’" , L . I-~*211111220 MICROCOP RESOLUTICN TEST CHART NATIONAL BUREAU 0I SANDARD ’l l 4 AtJLLW i V...include, but not be limited to, any element, substance, compound , or mixture, including disease- causing agents, which after release into the environment...under: (a) any substance designated pursuant to Section 311(b)(2)(A) of the Fed-- eral Water Pollution Control Act, (b) any element, compound , mixture

Low-Temperature Synthesis of Superconducting Nanocrystalline MgB 2

DOE PAGES

Lu, Jun; Xiao, Zhili; Lin, Qiyin; ...

2010-01-01

Magnesium diboride (MgB 2 ) is considered a promising material for practical application in superconducting devices, with a transition temperature near 40 K. In the present paper, nanocrystalline MgB 2 with an average particle size of approximately 70 nm is synthesized by reacting LiBH 4 with MgH 2 at temperatures as low as 450 ° C. This synthesis approach successfully bypasses the usage of either elemental boron or toxic diborane gas. The superconductivity of the nanostructures is confirmed by magnetization measurements, showing a superconducting critical temperature of 38.7 K.

Partial extinction of a conditioned context enhances preference for elements previously associated with cocaine but not with chocolate.

PubMed

Orsini, C; Bonito-Oliva, A; Montanari, C; Conversi, D; Cabib, S

2013-08-15

Drug-associated stimuli are crucial to reinstatement of drug-seeking after periods of abstinence, representing a central problem in treatment of addiction. The present study investigated the influence of partial extinction of the conditioned context on the expression of conditioned place preference (CPP). Mice of the inbred DBA/2J strain were conditioned with cocaine or chocolate in a context identified by multiple elements (A+B) and subsequently CPP expression was evaluated in a context containing only one element (A or B) or both (A+B). Cocaine- and chocolate-conditioned mice showed CPP in presence of the original compound stimulus. However, cocaine-conditioned mice did not show CPP when tested in A or B context, while chocolate-conditioned mice did show CPP to single element context. After conditioning mice were exposed to extinction training of the context A or B and then tested for CPP 1 and 9 days after the end of the extinction (days 9 and 18). Cocaine-conditioned mice showed CPP 9 days after extinction while chocolate-conditioned mice were relatively insensitive to the extinction procedure on day 1 after extinction, but they did not show CPP for the partial or the original compound 9 days after extinction. Cocaine-conditioned mice not submitted to the extinction training (simple passage of time) or submitted to a Sham-extinction procedure (saline injections and confinement in a new environment) did not show CPP on day 9 or 18. Cocaine-conditioned mice exposed to extinction training showed increased c-Fos expression in several brain areas in comparison to mice exposed to Sham-extinction. The extinction procedure did not specifically reduce behavioral sensitization. The results suggest that extinction training involving only elements of a drug-associated context can result in increased associative strength of those elements. © 2013.

Structural properties of lanthanide and actinide compounds within the plane wave pseudopotential approach

PubMed

Pickard; Winkler; Chen; Payne; Lee; Lin; White; Milman; Vanderbilt

2000-12-11

We show that plane wave ultrasoft pseudopotential methods readily extend to the calculation of the structural properties of lanthanide and actinide containing compounds. This is demonstrated through a series of calculations performed on UO, UO2, UO3, U3O8, UC2, alpha-CeC2, CeB6, CeSe, CeO2, NdB6, TmOI, LaBi, LaTiO3, YbO, and elemental Lu.

Studies of hot B subdwarfs. III - Carbon, nitrogen, and silicon abundances in three sdB stars

NASA Technical Reports Server (NTRS)

Lamontagne, R.; Wesemael, F.; Fontaine, G.; Sion, E. M.

1985-01-01

Optical and high-dispersion IUE observations of three hot B subdwarfs (UV 1758 + 36, Ton S-227, and Feige 65) are presented. These data are analyzed with model atmosphere techniques, and element abundances for C, N, and Si are derived. The abundances are either near (N) or below (C, Si) the solar value; large variations (1) in the extent of underabundances of carbon and silicon among the objects, as well as (2) in the abundances (with respect to the solar values) characterizing each star are observed. A preliminary interpretation of the observed variations in these and other hot subdwarfs in terms of radiative forces disrupting the downward diffusion of heavy elements is presented.

Enhanced analgesic effects of tramadol and common trace element coadministration in mice.

PubMed

Alexa, Teodora; Marza, Aurelia; Voloseniuc, Tudor; Tamba, Bogdan

2015-10-01

Chronic pain is managed mostly by the daily administration of analgesics. Tramadol is one of the most commonly used drugs, marketed in combination with coanalgesics for enhanced effect. Trace elements are frequent ingredients in dietary supplements and may enhance tramadol's analgesic effect either through synergic mechanisms or through analgesic effects of their own. Swiss Weber male mice were divided into nine groups and were treated with a combination of the trace elements Mg, Mn, and Zn in three different doses and a fixed dose of tramadol. Two groups served as positive (tramadol alone) and negative (saline) controls. Nociceptive assessment by tail-flick (TF) and hot-plate (HP) tests was performed at baseline and at 15, 30, 45, and 60 min after intraperitoneal administration. Response latencies were recorded and compared with the aid of ANOVA testing. All three trace elements enhanced tramadol's analgesic effect, as assessed by TF and HP test latencies. Coadministration of these trace elements led to an increase of approximately 30% in the average pain inhibition compared with the tramadol-alone group. The most effective doses were 0.6 mg/kg b.w. for Zn, 75 mg/kg b.w. for Mg, and 7.2 mg/kg b.w. for Mn. Associating trace elements such as Zn, Mg, and Mn with the standard administration of tramadol increases the drug's analgesic effect, most likely a consequence of their synergic action. These findings impact current analgesic treatment because the addition of these trace elements may reduce the tramadol dose required to obtain analgesia. © 2015 Wiley Periodicals, Inc.

34 CFR 460.2 - What programs are authorized by the Adult Education Act?

Code of Federal Regulations, 2014 CFR

2014-07-01

... by the Act: (a) Adult Education State-administered Basic Grant Program (34 CFR part 426). (b) State... 34 Education 3 2014-07-01 2014-07-01 false What programs are authorized by the Adult Education Act...) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION-GENERAL PROVISIONS...

34 CFR 460.2 - What programs are authorized by the Adult Education Act?

Code of Federal Regulations, 2013 CFR

2013-07-01

... by the Act: (a) Adult Education State-administered Basic Grant Program (34 CFR part 426). (b) State... 34 Education 3 2013-07-01 2013-07-01 false What programs are authorized by the Adult Education Act...) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION-GENERAL PROVISIONS...

34 CFR 460.2 - What programs are authorized by the Adult Education Act?

Code of Federal Regulations, 2011 CFR

2011-07-01

... by the Act: (a) Adult Education State-administered Basic Grant Program (34 CFR part 426). (b) State... 34 Education 3 2011-07-01 2011-07-01 false What programs are authorized by the Adult Education Act...) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION-GENERAL PROVISIONS...

34 CFR 460.2 - What programs are authorized by the Adult Education Act?

Code of Federal Regulations, 2012 CFR

2012-07-01

... by the Act: (a) Adult Education State-administered Basic Grant Program (34 CFR part 426). (b) State... 34 Education 3 2012-07-01 2012-07-01 false What programs are authorized by the Adult Education Act...) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION-GENERAL PROVISIONS...

Air Land Sea Bulletin, Issue No. 2013-2, Joint Close Air Support

DTIC Science & Technology

2013-05-01

game plan between his aircraft or element and the coor- dinated attack aircraft or element (s) for a specific JTAC/FAC(A) designated target. However...5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME...Service Department of Defense field agency sponsored by the US Army Train - ing and Doctrine Command (TRADOC), Marine Corps Combat Development Command

The Ballistic and Corrosion Evaluation of Magnesium Elektron E675 vs. Baseline Magnesium Alloy AZ31B and Aluminum Alloy 5083 for Armor Applications

DTIC Science & Technology

2011-06-01

critical property in reducing the plastic failure of the material. The ductility is marginally better than Mg AZ31B. 2 Table 1. Chemical...composition (%) of metal alloys. Element (%)/Alloy CPMg 9980B AZ31B-H24 AA5083-H131 Aluminum — 2.5–3.5 REM Manganese 0.10 max 0.2–1.0 0.40‒1.0 Zinc — 0.6...This trend was attributed to the lack of ductility in E675 compared to 5083, which reduced energy dissipation. Visual analysis of the Mg E675

76 FR 22302 - Airworthiness Directives; Airbus Model A310 Series Airplanes; and Model A300 B4-600, A300 B4-600R...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-21

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 39 [Docket No. FAA-2010... of 70mm (2.76 in). During the fatigue life demonstration of the THSA upper attachment primary load path elements, only a gimbal having a thickness of 70mm (2.76 in) was used. Thereafter, no additional...

Increasing Coverage of Hepatitis B Vaccination in China

PubMed Central

Wang, Shengnan; Smith, Helen; Peng, Zhuoxin; Xu, Biao; Wang, Weibing

2016-01-01

Abstract This study used a system evaluation method to summarize China's experience on improving the coverage of hepatitis B vaccine, especially the strategies employed to improve the uptake of timely birth dosage. Identifying successful methods and strategies will provide strong evidence for policy makers and health workers in other countries with high hepatitis B prevalence. We conducted a literature review included English or Chinese literature carried out in mainland China, using PubMed, the Cochrane databases, Web of Knowledge, China National Knowledge Infrastructure, Wanfang data, and other relevant databases. Nineteen articles about the effectiveness and impact of interventions on improving the coverage of hepatitis B vaccine were included. Strong or moderate evidence showed that reinforcing health education, training and supervision, providing subsidies for facility birth, strengthening the coordination among health care providers, and using out-of-cold-chain storage for vaccines were all important to improving vaccination coverage. We found evidence that community education was the most commonly used intervention, and out-reach programs such as out-of-cold chain strategy were more effective in increasing the coverage of vaccination in remote areas where the facility birth rate was respectively low. The essential impact factors were found to be strong government commitment and the cooperation of the different government departments. Public interventions relying on basic health care systems combined with outreach care services were critical elements in improving the hepatitis B vaccination rate in China. This success could not have occurred without exceptional national commitment. PMID:27175710

Increasing Coverage of Hepatitis B Vaccination in China: A Systematic Review of Interventions and Implementation Experiences.

PubMed

Wang, Shengnan; Smith, Helen; Peng, Zhuoxin; Xu, Biao; Wang, Weibing

2016-05-01

This study used a system evaluation method to summarize China's experience on improving the coverage of hepatitis B vaccine, especially the strategies employed to improve the uptake of timely birth dosage. Identifying successful methods and strategies will provide strong evidence for policy makers and health workers in other countries with high hepatitis B prevalence.We conducted a literature review included English or Chinese literature carried out in mainland China, using PubMed, the Cochrane databases, Web of Knowledge, China National Knowledge Infrastructure, Wanfang data, and other relevant databases.Nineteen articles about the effectiveness and impact of interventions on improving the coverage of hepatitis B vaccine were included. Strong or moderate evidence showed that reinforcing health education, training and supervision, providing subsidies for facility birth, strengthening the coordination among health care providers, and using out-of-cold-chain storage for vaccines were all important to improving vaccination coverage.We found evidence that community education was the most commonly used intervention, and out-reach programs such as out-of-cold chain strategy were more effective in increasing the coverage of vaccination in remote areas where the facility birth rate was respectively low. The essential impact factors were found to be strong government commitment and the cooperation of the different government departments.Public interventions relying on basic health care systems combined with outreach care services were critical elements in improving the hepatitis B vaccination rate in China. This success could not have occurred without exceptional national commitment.

Salicylic acid and aspirin inhibit the activity of RSK2 kinase and repress RSK2-dependent transcription of cyclic AMP response element binding protein- and NF-kappa B-responsive genes.

PubMed

Stevenson, M A; Zhao, M J; Asea, A; Coleman, C N; Calderwood, S K

1999-11-15

Sodium salicylate (NaSal) and other nonsteroidal anti-inflammatory drugs (NSAIDs) coordinately inhibit the activity of NF-kappa B, activate heat shock transcription factor 1 and suppress cytokine gene expression in activated monocytes and macrophages. Because our preliminary studies indicated that these effects could be mimicked by inhibitors of signal transduction, we have studied the effects of NSAIDs on signaling molecules potentially downstream of LPS receptors in activated macrophages. Our findings indicate that ribosomal S6 kinase 2 (RSK2), a 90-kDa ribosomal S6 kinase with a critical role as an effector of the RAS-mitogen-activated protein kinase pathway and a regulator of immediate early gene transcription is a target for inhibition by the NSAIDs. NSAIDs inhibited the activity of purified RSK2 kinase in vitro and of RSK2 in mammalian cells and suppressed the phosphorylation of RSK2 substrates cAMP response element binding protein (CREB) and I-kappa B alpha in vivo. Additionally, NaSal inhibited the phosphorylation by RSK2 of CREB and I-kappa B alpha on residues crucial for their transcriptional activity in vivo and thus repressed CREB and NF-kappa B-dependent transcription. These experiments suggest that RSK2 is a target for NSAIDs in the inhibition of monocyte-specific gene expression and indicate the importance of RSK2 and related kinases in cell regulation, indicating a new area for anti-inflammatory drug discovery.

Effect of the SiCl4 Flow Rate on SiBN Deposition Kinetics in SiCl4-BCl3-NH3-H2-Ar Environment

PubMed Central

Li, Jianping; Qin, Hailong; Liu, Yongsheng; Ye, Fang; Li, Zan; Cheng, Laifei; Zhang, Litong

2017-01-01

To improve the thermal and mechanical stability of SiCf/SiC or C/SiC composites with SiBN interphase, SiBN coating was deposited by low pressure chemical vapor deposition (LPCVD) using SiCl4-BCl3-NH3-H2-Ar gas system. The effect of the SiCl4 flow rate on deposition kinetics was investigated. Results show that deposition rate increases at first and then decreases with the increase of the SiCl4 flow rate. The surface of the coating is a uniform cauliflower-like structure at the SiCl4 flow rate of 10 mL/min and 20 mL/min. The surface is covered with small spherical particles when the flow rate is 30 mL/min. The coatings deposited at various SiCl4 flow rates are all X-ray amorphous and contain Si, B, N, and O elements. The main bonding states are B-N, Si-N, and N-O. B element and B-N bonding decrease with the increase of SiCl4 flow rate, while Si element and Si-N bonding increase. The main deposition mechanism refers to two parallel reactions of BCl3+NH3 and SiCl4+NH3. The deposition process is mainly controlled by the reaction of BCl3+NH3. PMID:28772986

Direct Density Functional Energy Minimization using an Tetrahedral Finite Element Grid

NASA Astrophysics Data System (ADS)

Vaught, A.; Schmidt, K. E.; Chizmeshya, A. V. G.

1998-03-01

We describe an O(N) (N proportional to volume) technique for solving electronic structure problems using the finite element method (FEM). A real--space tetrahedral grid is used as a basis to represent the electronic density, of a free or periodic system and Poisson's equation is solved as a boundary value problem. Nuclear cusps are treated using a local grid consisting of radial elements. These features facilitate the implementation of complicated energy functionals and permit a direct (constrained) energy minimization with respect to the density. We demonstrate the usefulness of the scheme by calculating the binding trends and polarizabilities of a number of atoms and molecules using a number of recently proposed non--local, orbital--free kinetic energy functionals^1,2. Scaling behavior, computational efficiency and the generalization to band--structure will also be discussed. indent 0 pt øbeylines øbeyspaces skip 0 pt ^1 P. Garcia-Gonzalez, J.E. Alvarellos and E. Chacon, Phys. Rev. B 54, 1897 (1996). ^2 A. J. Thakkar, Phys.Rev.B 46, 6920 (1992).

PACE. A Program for Acquiring Competence in Entrepreneurship. Part III: Being an Entrepreneur. Unit B: Financial Management. Research and Development Series No. 194 C-2.

ERIC Educational Resources Information Center

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

This three-part curriculum for entrepreneurship education is primarily for postsecondary level, including four-year colleges and adult education, but it can be adapted for special groups or vocational teacher education. The emphasis of the eight instructional units in Part III is operating a business. Unit B focuses on good financial management…

Regulatory elements involved in constitutive and phorbol ester-inducible expression of the plasminogen activator inhibitor type 2 gene promoter.

PubMed Central

Cousin, E; Medcalf, R L; Bergonzelli, G E; Kruithof, E K

1991-01-01

Gene transcription rates and mRNA levels of plasminogen activator inhibitor type 2 (PAI-2) are markedly induced by the tumor promoting agent phorbol 12-myristate 13-acetate (PMA) in human HT1080 fibrosarcoma cells. To identify promoter elements required for basal-, and phorbol ester-inducible expression, deletion mutants of the PAI-1 promoter fused to the chloramphenicol acetyl transferase (CAT) reporter gene, were transiently expressed in HT1080 cells. Constitutive CAT activity was expressed from constructs containing more than 215 bp of promoter sequence, whereas deletion to position -91 bp abolished CAT gene expression. Treatment of transfected cells with PMA resulted in a three- to ten-fold increase in CAT expression from all constructs except from the construct shortened to position -91. DNAse1 protection analysis of the promoter region between -215 and the transcription initiation site revealed numerous protected regions, including two AP1-like binding sites (AP1a and AP1b) and one CRE-like element. Site-directed mutagenesis of the AP1a site or of the CRE-like site resulted in the loss of basal CAT activity and abolished the PMA effect, whereas mutagenesis of AP1b only partially inhibited basal and PMA-mediated expression. Our results suggest that the PAI-2 promoter contains at least two elements required for basal gene transcription and PMA-mediated induction. Images PMID:1650454

Safety of long-term restrictive diets for peroxisomal disorders: vitamin and trace element status of patients treated for Adult Refsum Disease.

PubMed

Baldwin, E J; Harrington, D J; Sampson, B; Feher, M D; Wierzbicki, A S

2016-03-01

Adult Refsum's Disease (ARD) is caused by defects in the pathway for alpha-oxidation of phytanic acid (PA). Treatment involves restricting the dietary intake of phytanic acid by reducing the intake of dairy-derived fat. The adequacy of micronutrient intake in patients with ARD is unknown. Patients established on the Chelsea low-PA diet had general diet macronutrients, vitamins and trace elements assessed using 7-day-weighed intakes and serial 24-h recalls. Intakes were compared with biochemical assessments of nutritional status for haematinics (ferritin), trace elements (copper, zinc, iron, selenium), water- (vitamin B6 , B12 and folate) and fat-soluble vitamins (A, D, E and K). Eleven subjects (four women, seven men) were studied. Body mass index was 27 ± 5 kg/m(2) (range 19-38). All subjects had high sodium intakes (range 1873-4828 mg). Fat-soluble vitamin insufficiencies occurred in some individuals (vitamin A, n = 2; vitamin D, n = 6; vitamin E, n = 3; vitamin K, n = 10) but were not coincident. Vitamin B6 levels were normal or elevated (n = 6). Folate and 5-methyltetrahydrofolate concentrations were normal. Metabolic vitamin B12 insufficiency was suspected in four subjects based on elevated methylmalonic acid concentrations. Low copper and selenium intakes were noted in some subjects (n = 7, n = 2) but plasma levels were adequate. Iron, ferritin and zinc intakes and concentrations were normal. Subjects with ARD can be safely managed on the Chelsea low PA without routine micronutrient supplementation. Sodium intake should be monitored and reduced. Periodic nutritional screening may be necessary for fat-soluble vitamins, vitamin B12 , copper or selenium. © 2016 John Wiley & Sons Ltd.

Acta Aeronautica et Astronautica Sinica,

DTIC Science & Technology

1982-10-14

and the fatigue life of the rotor and the destabiliza- tion of the aerodynamic elasticity are entirely determined by the air- loads of the rotor. It...harmonics. In determining an and b n’ only u b.,,. a. b,., are taken into account and a.1 , b., b.L, In addition, we get 2, I + I P i u In the... determines the lateral distribution based on classical blade element theory. The calculated results usually show a lower total lift at higher speeds or a non

Self-management education interventions for patients with cancer: a systematic review.

PubMed

Howell, Doris; Harth, Tamara; Brown, Judy; Bennett, Cathy; Boyko, Susan

2017-04-01

This systematic review was intended to identify the effectiveness and inclusion of essential components of self-management education interventions to support patients with cancer in developing the skills needed for effective self-management of their disease and the acute or immediate, long-term, and late harmful effects of treatments. Self-management education interventions were included if they were randomized controlled trials (RCTs) containing at least one of the eight core elements outlined by the research team. A systematic search was conducted in Ovid MEDLINE (2005 through April 2015), Embase (2005 to 2015, week 15), the Cochrane Database of Systematic Reviews (Issue 4, April 2015), CINAHL (2005 to 2015) and PsychINFO (2005 to 2015). Keywords searched include 'self-management patient education' or 'patient education'. Forty-two RCTs examining self-management education interventions for patients with cancer were identified. Heterogeneity of interventions precluded meta-analysis, but narrative qualitative synthesis suggested that self-management education interventions improve symptoms of fatigue, pain, depression, anxiety, emotional distress and quality of life. Results for specific combinations of core elements were inconclusive. Very few studies used the same combinations of core elements, and among those that did, results were conflicting. Thus, conclusions as to the components or elements of self-management education interventions associated with the strength of the effects could not be assessed by this review. Defining the core components of cancer self-management education and the fundamental elements for inclusion in supporting effective self-management will be critical to ensure consistent and effective provision of self-management support in the cancer system.

Computational design and elaboration of a de novo heterotetrameric alpha-helical protein that selectively binds an emissive abiological (porphinato)zinc chromophore.

PubMed

Fry, H Christopher; Lehmann, Andreas; Saven, Jeffery G; DeGrado, William F; Therien, Michael J

2010-03-24

The first example of a computationally de novo designed protein that binds an emissive abiological chromophore is presented, in which a sophisticated level of cofactor discrimination is pre-engineered. This heterotetrameric, C(2)-symmetric bundle, A(His):B(Thr), uniquely binds (5,15-di[(4-carboxymethyleneoxy)phenyl]porphinato)zinc [(DPP)Zn] via histidine coordination and complementary noncovalent interactions. The A(2)B(2) heterotetrameric protein reflects ligand-directed elements of both positive and negative design, including hydrogen bonds to second-shell ligands. Experimental support for the appropriate formulation of [(DPP)Zn:A(His):B(Thr)](2) is provided by UV/visible and circular dichroism spectroscopies, size exclusion chromatography, and analytical ultracentrifugation. Time-resolved transient absorption and fluorescence spectroscopic data reveal classic excited-state singlet and triplet PZn photophysics for the A(His):B(Thr):(DPP)Zn protein (k(fluorescence) = 4 x 10(8) s(-1); tau(triplet) = 5 ms). The A(2)B(2) apoprotein has immeasurably low binding affinities for related [porphinato]metal chromophores that include a (DPP)Fe(III) cofactor and the zinc metal ion hemin derivative [(PPIX)Zn], underscoring the exquisite active-site binding discrimination realized in this computationally designed protein. Importantly, elements of design in the A(His):B(Thr) protein ensure that interactions within the tetra-alpha-helical bundle are such that only the heterotetramer is stable in solution; corresponding homomeric bundles present unfavorable ligand-binding environments and thus preclude protein structural rearrangements that could lead to binding of (porphinato)iron cofactors.

Transferring elements of a density matrix

DOE Office of Scientific and Technical Information (OSTI.GOV)

Allahverdyan, Armen E.; Hovhannisyan, Karen V.; Yerevan State University, A. Manoogian Street 1, Yerevan

2010-01-15

We study restrictions imposed by quantum mechanics on the process of matrix-element transfer. This problem is at the core of quantum measurements and state transfer. Given two systems A and B with initial density matrices lambda and r, respectively, we consider interactions that lead to transferring certain matrix elements of unknown lambda into those of the final state r-tilde of B. We find that this process eliminates the memory on the transferred (or certain other) matrix elements from the final state of A. If one diagonal matrix element is transferred, r(tilde sign){sub aa}=lambda{sub aa}, the memory on each nondiagonal elementmore » lambda{sub an}ot ={sub b} is completely eliminated from the final density operator of A. Consider the following three quantities, Relambda{sub an}ot ={sub b}, Imlambda{sub an}ot ={sub b}, and lambda{sub aa}-lambda{sub bb} (the real and imaginary part of a nondiagonal element and the corresponding difference between diagonal elements). Transferring one of them, e.g., Rer(tilde sign){sub an}ot ={sub b}=Relambda{sub an}ot ={sub b}, erases the memory on two others from the final state of A. Generalization of these setups to a finite-accuracy transfer brings in a trade-off between the accuracy and the amount of preserved memory. This trade-off is expressed via system-independent uncertainty relations that account for local aspects of the accuracy-disturbance trade-off in quantum measurements. Thus, the general aspect of state disturbance in quantum measurements is elimination of memory on non-diagonal elements, rather than diagonalization.« less

Early Childhood Physical Education. The Essential Elements.

ERIC Educational Resources Information Center

Gabbard, Carl

1988-01-01

Details are presented regarding the essential elements of an effective early childhood physical education curriculum. Components include movement awareness, fundamental locomotor skills, fundamental nonlocomotor skills, fundamental manipulative skills, and health-related fitness. (CB)

Differential tissue distribution, developmental programming, estrogen regulation and promoter characteristics of cyp19 genes in teleost fish.

PubMed

Callard, G V; Tchoudakova, A V; Kishida, M; Wood, E

2001-12-01

Teleost fish are characterized by exceptionally high levels of brain estrogen biosynthesis when compared to the brains of other vertebrates or to the ovaries of the same fish. Goldfish (Carassius auratus) and zebrafish (Danio rerio) have utility as complementary models for understanding the molecular basis and functional significance of exaggerated neural estrogen biosynthesis. Multiple cytochrome P450 aromatase (P450arom) cDNAs that derive from separate gene loci (cyp19a and cyp19b) are differentially expressed in brain (P450aromB>A) and ovary (P450aromA>B) and have a different developmental program (B>A) and response to estrogen upregulation (B only). As measured by increased P450aromB mRNA, a functional estrogen response system is first detected 24-48 h post-fertilization (hpf), consistent with the onset of estrogen receptor (ER) expression (alpha, beta, and gamma). The 5'-flanking region of the cyp19b gene has a TATA box, two estrogen response elements (EREs), an ERE half-site (ERE1/2), a nerve growth factor inducible-B protein (NGFI-B)/Nur77 responsive element (NBRE) binding site, and a sequence identical to the zebrafish GATA-2 gene neural specific enhancer. The cyp19a promoter region has TATA and CAAT boxes, a steroidogenic factor-1 (SF-1) binding site, and two aryl hydrocarbon receptor (AhR)/AhR nuclear translocator factor (ARNT) binding motifs. Both genes have multiple potential SRY/SOX binding sites (16 and 8 in cyp19b and cyp19a, respectively). Luciferase reporters have basal promoter activity in GH3 cells, but differences (a>b) are opposite to fish pituitary (b>a). When microinjected into fertilized zebrafish eggs, a cyp19b promoter-driven green fluorescent protein (GFP) reporter (but not cyp19a) is expressed in neurons of 30-48 hpf embryos, most prominently in retinal ganglion cells (RGCs) and their projections to optic tectum. Further studies are required to identify functionally relevant cis-elements and cellular factors, and to determine the regulatory role of estrogen in neurodevelopment.

34 CFR 300.2 - Applicability of this part to State and local agencies.

Code of Federal Regulations, 2013 CFR

2013-07-01

... the rights and protections under Part B of the Act are given to children with disabilities— (1... THE EDUCATION OF CHILDREN WITH DISABILITIES General Purposes and Applicability § 300.2 Applicability... education of children with disabilities, including: (i) The State educational agency (SEA). (ii) Local...

34 CFR 300.2 - Applicability of this part to State and local agencies.

Code of Federal Regulations, 2014 CFR

2014-07-01

... the rights and protections under Part B of the Act are given to children with disabilities— (1... THE EDUCATION OF CHILDREN WITH DISABILITIES General Purposes and Applicability § 300.2 Applicability... education of children with disabilities, including: (i) The State educational agency (SEA). (ii) Local...

34 CFR 300.2 - Applicability of this part to State and local agencies.

Code of Federal Regulations, 2012 CFR

2012-07-01

... the rights and protections under Part B of the Act are given to children with disabilities— (1... THE EDUCATION OF CHILDREN WITH DISABILITIES General Purposes and Applicability § 300.2 Applicability... education of children with disabilities, including: (i) The State educational agency (SEA). (ii) Local...

Building Customized University-to-Business (U2B) Partnerships

ERIC Educational Resources Information Center

Irvine, George; Verma, Lisa

2013-01-01

Continuing education (CE) units throughout the United States have successfully built University-to-Business (U2B) partnerships to provide greater value to their community partners and to increase revenue for the university. Our experience in building U2B partnerships and feedback from our partners--businesses, corporations, state agencies, and…

Experimental characterization of the constitutive materials of MgB2 multi-filamentary wires for the development of 3D numerical models

NASA Astrophysics Data System (ADS)

Escamez, Guillaume; Sirois, Frédéric; Tousignant, Maxime; Badel, Arnaud; Granger, Capucine; Tixador, Pascal; Bruzek, Christian-Éric

2017-03-01

Today MgB2 superconducting wires can be manufactured in long lengths at low cost, which makes this material a good candidate for large scale applications. However, because of its relatively low critical temperature (less than 40 K), it is necessary to operate MgB2 devices in a liquid or gaseous helium environment. In this context, losses in the cryogenic environment must be rigorously minimized, otherwise the use of a superconductor is not worthy. An accurate estimation of the losses at the design stage is therefore mandatory in order to allow determining the device architecture that minimizes the losses. In this paper, we present a complete a 3D finite element model of a 36-filament MgB2 wire based on the architecture of the Italian manufacturer Colombus. In order for the model to be as accurate as possible, we made a substantial effort to characterize all constitutive materials of the wire, namely the E-J characteristics of the MgB2 filaments and the electric and magnetic properties (B-H curves) of nickel and monel, which are the two major non-superconducting components of the wire. All properties were characterized as a function of temperature and magnetic field. Limitations of the characterization and of the model are discussed, in particular the difficulty to extract the maximum relative permeability of nickel and monel from the experimental data, as well as the lack of a thin conductive layer model in the 3D finite element method, which prevents us from taking into account the resistive barriers around the MgB2 filaments in the matrix. Two examples of numerical simulations are provided to illustrate the capabilities of the model in its current state.

41 CFR Appendix B to Part 102 - 37-Elements of a State Plan of Operation

Code of Federal Regulations, 2013 CFR

2013-07-01

... Plan of Operation B Appendix B to Part 102 Public Contracts and Property Management Federal Property... SURPLUS PERSONAL PROPERTY Pt. 102-37, App. B Appendix B to Part 102-37—Elements of a State Plan of... title of the State official who directly supervises the State agent. (b) Operational authority Include...

Drill core major, trace and rare earth element anlayses from wells RN-17B and RN-30, Reykjanes, Iceland

DOE Data Explorer

Andrew Fowler

2015-04-01

Analytical results for X-ray fluorescence (XRF) and inductively coupled plasma mass spectrometry (ICP-MS) measurement of major, trace and rare earth elements in drill core from geothermal wells in Reykjanes, Iceland. Total Fe was analyzed as FeO, therefore is not included under the Fe2O3 column.

Drill cutting and core major, trace and rare earth element anlayses from wells RN-17B and RN-30, Reykjanes, Iceland

DOE Data Explorer

Andrew Fowler

2015-05-01

Analytical results for x-ray fluorescence (XRF) and Inductively Couple Plasma Mass Spectrometry (ICP-MS) measurement of major, trace and rare earth elements in drill cuttings from geothermal wells in Reykjanes, Iceland. Total Fe was analyzed as FeO, therefore is not included under the Fe2O3 column.

Origin and Evolution of the Elements

NASA Astrophysics Data System (ADS)

McWilliam, Andrew; Rauch, Michael

2004-09-01

Introduction; List of participants; 1. Mount Wilson Observatory contributions to the study of cosmic abundances of the chemical elements George W. Preston; 2. Synthesis of the elements in stars: B2FH and beyond E. Margaret Burbidge; 3. Stellar nucleosynthesis: a status report 2003 David Arnett; 4. Advances in r-process nucleosynthesis John J. Cowan and Christopher Sneden; 5. Element yields of intermediate-mass stars Richard B. C. Henry; 6. The impact of rotation on chemical abundances in red giant branch stars Corinne Charbonnel; 7. s-processing in AGB stars and the composition of carbon stars Maurizio Busso, Oscar Straniero, Roberto Gallino, and Carlos Abia; 8. Models of chemical evolution Francesca Matteucci; 9. Model atmospheres and stellar abundance analysis Bengt Gustafsson; 10. The light elements: lithium, beryllium, and boron Ann Merchant Boesgaard; 11. Extremely metal-poor stars John E. Norris; 12. Thin and thick galactic disks Poul E. Nissen; 13. Globular clusters and halo field stars Christopher Sneden, Inese I. Ivans and Jon P. Fulbright; 14. Chemical evolution in ω Centauri Verne V. Smith; 15. Chemical composition of the Magellanic Clouds, from young to old stars Vanessa Hill; 16. Detailed composition of stars in dwarf spheroidal galaxies Matthew D. Shetrone; 17. The evolutionary history of Local Group irregular galaxies Eva K. Grebel; 18. Chemical evolution of the old stellar populations of M31 R. Michael Rich; 19. Stellar winds of hot massive stars nearby and beyond the Local Group Fabio Bresolin and Rolf P. Kudritzki; 20. Presolar stardust grains Donald D. Clayton and Larry R. Nittler; 21. Interstellar dust B. T. Draine; 22. Interstellar atomic abundances Edward B. Jenkins; 23. Molecules in the interstellar medium Tommy Wiklind; 24. Metal ejection by galactic winds Crystal L. Martin; 25. Abundances from the integrated light of globular clusters and galaxies Scott C. Trager; 26. Abundances in spiral and irregular galaxies Donald R. Garnett; 27. Chemical composition of the intracluster medium Michael Loewenstein; 28. Quasar elemental abundances and host galaxy evolution Fred Hamann, Matthias Dietrich, Bassem M. Sabra, and Craig Warner; 29. Chemical abundances in the damped Lyα systems Jason X. Prochaska; 30. Intergalactic medium abundances Robert F. Carswell; 31. Conference summary Bernard E. J. Pagel.

Taking Part in Technology Education: Elements in Students' Motivation

ERIC Educational Resources Information Center

Autio, Ossi; Hietanoro, Jenni; Ruismaki, Heikki

2011-01-01

The purpose of this study was to determine the elements motivating comprehensive school students to study technology education. In addition, we tried to discover how students' motivation towards technology education developed over the period leading up to their school experience and the effect this might have on their future involvement with…

Necessary Elements of Civic Engagement in Teacher Education

ERIC Educational Resources Information Center

Fernlund, Phyllis

2011-01-01

In this paper, the author discusses the necessary elements of civic engagement in teacher education and responsibility for schools. For over 50 years, John Goodlad conducted research, created an institute to study education in a democratic society, and formed 25 partnership sites to engage in research and practice. The National Network for Renewal…

Principle Elements of Curriculum in the Preschool Pattern of Montessori

ERIC Educational Resources Information Center

Bahmaee, Azizollah Baboli; Saadatmand, Zohreh; Yarmohammadian, Mohammad Hossein

2016-01-01

Montessori the physician and educational philosopher was probably one of the most prominent and famous education theorizer in the field of preschool education. Current research attempts to extract and clarify the major elements of curriculum by reliance on Montessori viewpoints. In this paper first the philosophical basics of preschool education…

Chemical stability study of vitamins thiamine, riboflavin, pyridoxine and ascorbic acid in parenteral nutrition for neonatal use

PubMed Central

2011-01-01

Background The objective of this work was to study the vitamins B1, B2, B6 and C stability in a pediatric formulation containing high amounts of calcium in the presence of organic phosphate, amino acids, glucose, sodium chloride, magnesium sulfate, pediatric vitamins and trace elements under different conditions using developed and validated analytical methods. Methods The study was carried out during 72 h with formulations packaged in recommended storage temperature (4°C) and 25°C, with and without photoprotection. Results The results showed that the methodologies used for assessing the chemical stability of vitamins B1, B2, B6 and C in the formulation were selective, linear, precise and accurate. The vitamins could be considered stable in the formulation during the three days of study if stored at 4°C. When stored at 25°C vitamin C presented instability after 48 h. Conclusion The pediatric formulation containing high amount of calcium in the presence of organic phosphate, amino acids, glucose, sodium chloride, magnesium sulphate, pediatric vitamins and trace elements packaged in bag-type trilaminate presented a shelf life of the 72 h, when maintained under refrigeration, between 2°C and 8°C. This shelf life was measured considering the vitamins studied. Further studies are needed including all the vitamins present in this formulation. PMID:21569609

DOE Office of Scientific and Technical Information (OSTI.GOV)

Karayigit, A.I.; Bulut, Y.; Karayigit, G.

A total of 48 samples, feed coals (FCs), fly ashes (FAs) and bottom ashes (BAs), which were systematically collected once a week over an eight-week period from boiler units, B1-4 with 660 MW and B5-6 with 330 MW capacity from Soma power plant, have been evaluated for major and trace elements (Al, Ca, Fe, K, Mg, Mn, Na, Ti, S, As, B, Ba, Be, Bi, Cd, Co, Cr, Cu, Cs, Ga, Ge, Hf, Hg, Li, Mo, Nb, Ni, P, Pb, Rb, Sb, Sc, Se, Sn, Sr, Ta, Th, Tl, U, V, Y, Zn, Zr, and REEs) to get information onmore » behavior during coal combustion. This study indicates that some elements such as Hg, Bi, Cd, As, Pb, Ge, Tl, Sn, Zn, Sb, B show enrichments in FAs relative to the BAs in both group boiler units. In addition to these, Cs, Lu, Tm, and Ga in Units B1-4 and S in Units B5-6 also have enrichments in FAs. Elements showing enrichments in BAs in both group boiler units are Ta, Mn, Nb. In addition to these, Se, Ca, Mg, Na, Fe in Units B1-4 and Cu in Units B5-6 also have enrichments in BAs. The remaining elements investigated in this study have no clear segregation between FAs and BAs. Mass balance calculations with the two methods show that some elements, S, Ta, Hg, Se, Zn, Na, Ca in Units B1-4, and Hg, S, Ta, Se, P in Units B5-6, have volatile behavior during coal combustion in the Soma power plant. This study also implies that some elements, Sb and Tb in Units B1-4 and Sb in Units B5-6, have relatively high retention effects in the combustion residues from the Soma power plant.« less

Hydrogenation of Carbon Dioxide Catalyzed by Ruthenium Trimethylphosphine Complexes: A Mechanistic Investigation using High-Pressure NMR Spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Getty, April D.; Tai, Chih-Cheng; Linehan, John C.

2009-08-26

The previously reported complex, cis-(PMe3)4RuCl(OAc) (1) acts as a catalyst for CO2 hydrogenation into formic acid in the presence of a base and an alcohol co-catalyst. NMR spectroscopy has revealed that 1 exists in solution in equilibrium with fac-(PMe3)3RuCl(h2-OAc) (2), [(PMe3)4Ru(h2-OAc)]Cl (3a), and free PMe3. Complex 2 has been isolated and characterized by elemental analysis, NMR spectroscopy, and X-ray crystallography. 2 has been tested as a CO2 hydrogenation catalyst, however, it performed poorly under the conditions of catalysis used for 1. Complex 3a can be prepared by adding certain alcohols, such as MeOH, EtOH, or o-C6H5OH, to a solution ofmore » 1 in CDCl3. The chloride ion of 3a has been exchanged for the non-coordinating anions BPh4 or B(ArF )4 (B(ArF)4 = tetrakis(3,5-bis(trifluoromethyl)phenyl)borate) to produce [(PMe3)4Ru(h2-OAc)]BPh4 (3b) and [(PMe3)4Ru(h2-OAc)]B(ArF)4 (3c). Both of these complexes have been isolated and characterized by elemental analysis, NMR spectroscopy, and in the case of 3b, X-ray crystallography. Complexes 3b and 3c perform just as well as 1 for CO2 hydrogenation to formic acid in the presence of an alcohol co-catalyst; however, 3b,c perform equally well without the added alcohol. High-pressure NMR has been used to investigate the mechanism of CO2 hydrogenation via 3a,b in the presence of base. Two of the intermediates involved have been identified as cis-(PMe3)4RuH2 (5) and cis-(PMe3)4Ru(H)O2CH (6), and the role of the base includes not only trapping of the formic acid product, but also initiation of the catalysis by aiding the conversion of 3b,c to 5.« less

EFFECT OF ANNEALING TEMPERATURE ON THE STRUCTURE AND AC MAGNETIC PROPERTIES OF Fe73Cu1Nb3.5-xVxSi13.5B9 (x = 1.0, 1.5, 2.0) NANOCRYSTALLINE SOFT MAGNETIC ALLOYS

NASA Astrophysics Data System (ADS)

Lu, Wei; Huang, Ping; Wang, Yuxin; Yan, Biao

2013-07-01

In this paper, Nb element was partially replaced by V element in Finemet-type Fe73Cu1Nb3.5-xVxSi13.5B9 (x = 1, 1.5, 2) alloys and the effect of annealing temperatures on the microstructure and AC magnetic properties of the samples are studied. The annealing temperatures affect the grain sizes of the bcc α-Fe phase greatly. When the annealing temperature is between 540-560°C, the samples have better AC magnetic properties than the samples annealed at other temperatures. The optimized annealing temperature of the studied samples is around 560°C. The coercivity and iron loss of the V2 sample is a little bit higher than that of V1 and V1.5 alloys while the amplitude permeability of V2 alloy is larger than that of V1 and V1.5, which indicate that the content of V element has strong influence on the magnetic properties of nanocrystalline soft magnetic alloys.

2 CFR 25.345 - Nonprofit organization.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Nonprofit organization. 25.345 Section 25... primarily for scientific, educational, service, charitable, or similar purposes in the public interest; (2... operations of the organization. (b) Includes nonprofit— (1) Institutions of higher education; (2) Hospitals...

Children in and out of School: Ethnography and Education. Language and Ethnography Series, Volume 2. Colloquium on Ethnography and Education (Philadelphia, PA, 1978).

ERIC Educational Resources Information Center

Gilmore, Perry, Ed.; Glatthorn, Allan A., Ed.

The following articles on ethnography and education are presented: (1) "A Retrospective Discussion of the State of the Art in Ethnography in Education," by P. Gilmore and D. M. Smith; (2) "Ethnography in Education: Defining the Essentials," by S. B. Heath; (3) "The Structure of Classroom Events and Their Consequences for Student Performance," by…

[Finite element analysis of the maxillary central incisor with traditional and modified crown lengthening surgery and post-core restoration in management of crown-root fracture].

PubMed

Zhen, M; Wei, Y P; Hu, W J; Rong, Q G; Zhang, H

2016-06-01

To construct three-dimensional finite element models with modified crown lengthening surgery and post-core restoration in management of various crown-root fracture types, to investigate the intensity and distribution of stressin models mentioned above, and to compare and analyze the indications of traditional and modified crown lengthening surgeries from the mechanic point of view. Nine three-dimensional finite element models with modified crown lengthening surgery and post-core restoration were established and analyzed by micro-CT scanning technique, dental impression scanner, Mimics 10.0, Geomagic studio 9.0 and ANSYS 14.0 software. The von Mises stress of dentin, periodontal ligament, alveolar bone, post and core, as well as the periodontal ligament area and threshold limit value were calculated and compared with the findings of traditional crown lengthening models which had been published earlierby our research group. The von Mises stress intensity of modified crown lengthening models were: dentin>post>core>alveolar bone>periodontal ligament. The maximum von Mises stress of dentin(44.37-80.58 MPa)distributed in lingual central shoulder. The periodontal ligament area of the modified crown lengthening surgery was reduced by 6% to 28%, under the same crown-root fracture conditions, the periodontal ligament area of modified crown lengthening models was larger than that of the traditional crown lengthening models. In modified crown lengthening surgery models, the von Mises stress of periodontal ligament of B3L1m, B3L2m, B3L3m models exceeded their limit values, however, the von Mises stress of periodontal ligament of the B2L2c, B2L3c, B3L1c, B3L2c, B3L3c models exceeded their limit values in traditional crown lengthening surgery models. The modified crown lengthening surgery conserves more periodontal supporting tissues, which facilitates the long-term survival of teeth. The indication of modified crown lengthening surgery is wider than traditional method. The maxillary central incisors with labial fracture at gingival margin level and with palatal fracture at or below the alveolar crest level are not the indication of the crown lengthening surgery.

Lattice QCD calculation of the B(s )→D(s) *ℓν form factors at zero recoil and implications for |Vc b|

NASA Astrophysics Data System (ADS)

Harrison, Judd; Davies, Christine T. H.; Wingate, Matthew; Hpqcd Collaboration

2018-03-01

We present results of a lattice QCD calculation of B →D* and Bs→Ds* axial vector matrix elements with both states at rest. These zero recoil matrix elements provide the normalization necessary to infer a value for the CKM matrix element |Vc b| from experimental measurements of B¯ 0→D*+ℓ-ν ¯ and B¯s0→Ds*+ℓ-ν¯ decay. Results are derived from correlation functions computed with highly improved staggered quarks (HISQ) for light, strange, and charm quark propagators, and nonrelativistic QCD for the bottom quark propagator. The calculation of correlation functions employs MILC Collaboration ensembles over a range of three lattice spacings. These gauge field configurations include sea quark effects of charm, strange, and equal-mass up and down quarks. We use ensembles with physically light up and down quarks, as well as heavier values. Our main results are FB→D *(1 )=0.895 ±0.01 0stat±0.024sys and FBs→Ds*(1 )=0.883 ±0.01 2stat±0.02 8sys . We discuss the consequences for |Vc b| in light of recent investigations into the extrapolation of experimental data to zero recoil.

ABF2, an ABRE-binding bZIP factor, is an essential component of glucose signaling and its overexpression affects multiple stress tolerance.

PubMed

Kim, Sunmi; Kang, Jung-Youn; Cho, Dong-Im; Park, Ji Hye; Kim, Soo Young

2004-10-01

Phytohormone abscisic acid (ABA) regulates stress-responsive gene expression during vegetative growth, which is mediated largely by cis-elements sharing the ACGTGGC consensus. Although many transcription factors are known to bind the elements in vitro, only a few have been demonstrated to have in vivo functions and their specific roles in ABA/stress responses are mostly unknown. Here, we report that ABF2, an ABF subfamily member of bZIP proteins interacting with the ABA-responsive elements, is involved in ABA/stress responses. Its overexpression altered ABA sensitivity, dehydration tolerance, and the expression levels of ABA/stress-regulated genes. Furthermore, ABF2 overexpression promoted glucose-induced inhibition of seedling development, whereas its mutation impaired glucose response. The reduced sugar sensitivity was not observed with mutants of two other ABF family members, ABF3 and ABF4. Instead, these mutants displayed defects in ABA, salt, and dehydration responses, which were not observed with the abf2 mutant. Our data indicate distinct roles of ABF family members: whereas ABF3 and ABF4 play essential roles in ABA/stress responses, ABF2 is required for normal glucose response. We also show that ABF2 overexpression affects multiple stress tolerance.

28 CFR 115.33 - Inmate education.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Inmate education. 115.33 Section 115.33... Standards for Adult Prisons and Jails Training and Education § 115.33 Inmate education. (a) During the... harassment. (b) Within 30 days of intake, the agency shall provide comprehensive education to inmates either...

28 CFR 115.33 - Inmate education.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Inmate education. 115.33 Section 115.33... Standards for Adult Prisons and Jails Training and Education § 115.33 Inmate education. (a) During the... harassment. (b) Within 30 days of intake, the agency shall provide comprehensive education to inmates either...

28 CFR 115.33 - Inmate education.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Inmate education. 115.33 Section 115.33... Standards for Adult Prisons and Jails Training and Education § 115.33 Inmate education. (a) During the... harassment. (b) Within 30 days of intake, the agency shall provide comprehensive education to inmates either...

Irish Educational Studies. Vol. 4 No. 2.

ERIC Educational Resources Information Center

McKernan, Jim, Ed.

1984-01-01

The following papers dealing with education in Ireland are presented: "The Educational agenda: A View of the Future" (H. T. Sockett); "Curriculum and Policy in Irish Post-Primary Education" (B. O'Reilly); "A Response to Barney O'Reilly on Curriculum and Policy in Irish Post-Primary Education" (D. G. Mulcahy);…

Endoplasmic Reticulum-Associated Degradation Factor ERLIN2: Oncogenic Roles and Molecular Targeting of Breast Cancer

DTIC Science & Technology

2013-06-01

Targeting of Breast Cancer 5a. CONTRACT NUMBER W81XWH-10-1-0152 5b. GRANT NUMBER W81XWH-10-1-0152 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Zeng... Element -Binding Protein 1c (SREBP1c), the key lipogenic trans-activator; (4) ERLIN2 regulates activation of SREBP1c by interacting with Insulin...the major samples are gene amplified and/or over-expressed (pɘ.05). This new data further supports the findings that ERLIN2 plays an important

Evaluation of the 34S/32S ratio of Soufre de Lacq elemental sulfur isotopic reference material by continuous flow isotope-ratio mass spectrometry

USGS Publications Warehouse

Qi, H.P.; Coplen, T.B.

2003-01-01

Soufre de Lacq elemental sulfur reference material (IAEA-S-4) isotopically is homogeneous in amounts as small as 41 ??g as determined by continuous flow isotope-ratio mass spectrometry. The ??34S value for this reference material is +16.90 ?? 0.12??? (1??) on a scale (Vienna Can??on Diablo troilite, VCDT) where IAEA-S-1 Ag2S is -0.3??? and IAEA-S-2 Ag2S is +22.67???. Published by Elsevier Science B.V.

6 CFR 17.415 - Access to course offerings.

Code of Federal Regulations, 2010 CFR

2010-01-01

... students on such basis, including health, physical education, industrial, business, vocational, technical, home economics, music, and adult education courses. (b)(1) With respect to physical education classes..., 2003. (2) This section does not prohibit grouping of students in physical education classes and...

28 CFR 54.415 - Access to course offerings.

Code of Federal Regulations, 2010 CFR

2010-07-01

... basis, including health, physical education, industrial, business, vocational, technical, home economics, music, and adult education courses. (b)(1) With respect to classes and activities in physical education... September 29, 2000. (2) This section does not prohibit grouping of students in physical education classes...

38 CFR 21.4260 - Courses in foreign countries.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Administration of Educational Assistance Programs Courses...) must also meet all of the provisions of paragraph (b) of this section. (i) The educational institution... Organization (WHO). (2) The evaluating bodies (such as medical associations or educational agencies) whose...

The 3D Structure of the Immunoglobulin Heavy-Chain Locus: Implications for Long-Range Genomic Interactions

PubMed Central

Jhunjhunwala, Suchit; van Zelm, Menno C.; Peak, Mandy M.; Cutchin, Steve; Riblet, Roy; van Dongen, Jacques J.M.; Grosveld, Frank G.; Knoch, Tobias A.; Murre, Cornelis

2009-01-01

SUMMARY The immunoglobulin heavy-chain (Igh) locus is organized into distinct regions that contain multiple variable (VH), diversity (DH), joining (JH) and constant (CH) coding elements. How the Igh locus is structured in 3D space is unknown. To probe the topography of the Igh locus, spatial distance distributions were determined between 12 genomic markers that span the entire Igh locus. Comparison of the distance distributions to computer simulations of alternative chromatin arrangements predicted that the Igh locus is organized into compartments containing clusters of loops separated by linkers. Trilateration and triple-point angle measurements indicated the mean relative 3D positions of the VH, DH, JH, and CH elements, showed compartmentalization and striking conformational changes involving VH and DH-JH elements during early B cell development. In pro-B cells, the entire repertoire of VH regions (2 Mbp) appeared to have merged and juxtaposed to the DH elements, mechanistically permitting long-range genomic interactions to occur with relatively high frequency. PMID:18423198

A Walk through Graduate Education: Selected Papers and Speeches of Jules B. LaPidus, President of the Council of Graduate Schools, 1984-2000.

ERIC Educational Resources Information Center

Hamblin, Jane A., Ed.

This book was created to honor Jules B. LaPidus, retiring president of the Council of Graduate Education, and to preserve his writings and speeches. The papers and speeches of Part 1 show how the author addressed the topical issues of graduate education, moving from observation to direction on research, funding, and preparation of faculty. Part 2…

Pulsed Power Education

DTIC Science & Technology

1983-06-01

JUN 1983 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE Pulsed Power Education 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c...1976-2013, and Abstracts of the 2013 IEEE International Conference on Plasma Science. Held in San Francisco, CA on 16-21 June 2013. U.S. Government or...unclassified b. ABSTRACT unclassified c. THIS PAGE unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 PULSED POWER EDUCATION * M

PACE. A Program for Acquiring Competence in Entrepreneurship. Part I: Getting Ready to Become an Entrepreneur. Unit B: Are You an Entrepreneur? Research and Development Series No. 194 A-2.

ERIC Educational Resources Information Center

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

This three-part curriculum for entrepreneurship education is primarily for postsecondary level, including four-year colleges and adult education, but it can be adapted for special groups or vocational teacher education. The emphasis of the three instructional units in Part I is understanding businesses. Unit B focuses on individual and…

Room-Temperature Fabricated Thin-Film Transistors Based on Compounds with Lanthanum and Main Family Element Boron.

PubMed

Xiao, Peng; Huang, Junhua; Dong, Ting; Xie, Jianing; Yuan, Jian; Luo, Dongxiang; Liu, Baiquan

2018-06-06

For the first time, compounds with lanthanum from the main family element Boron (LaB x ) were investigated as an active layer for thin-film transistors (TFTs). Detailed studies showed that the room-temperature fabricated LaB x thin film was in the crystalline state with a relatively narrow optical band gap of 2.28 eV. The atom ration of La/B was related to the working pressure during the sputtering process and the atom ration of La/B increased with the increase of the working pressure, which will result in the freer electrons in the LaB x thin film. LaB x -TFT without any intentionally annealing steps exhibited a saturation mobility of 0.44 cm²·V −1 ·s −1 , which is a subthreshold swing ( SS ) of 0.26 V/decade and a I on / I off ratio larger than 10⁴. The room-temperature process is attractive for its compatibility with almost all kinds of flexible substrates and the LaB x semiconductor may be a new choice for the channel materials in TFTs.

Electronic structure, phase transitions and diffusive properties of elemental plutonium

NASA Astrophysics Data System (ADS)

Setty, Arun; Cooper, B. R.

2003-03-01

We present a SIC-LDA-LMTO based study of the electronic structure of the delta, alpha and gamma phases of plutonium, and also of the alpha and gamma phases of elemental cerium. We find excellent agreement with the experimental densities and magnetic properties [1]. Furthermore, detailed studies of the computational densities of states for delta plutonium, and comparison with the experimental photoemission spectrum [2], provide evidence for the existence of an unusual fluctuating valence state. Results regarding the vacancy formation and self-diffusion in delta plutonium will be presented. Furthermore, a study of interface diffusion between plutonium and steel (technologically relevant in the storage of spent fuel) or other technologically relevant alloys will be included. Preliminary results regarding gallium stabilization of delta plutonium, and of plutonium alloys will be presented. [1] M. Dormeval et al., private communication (2001). [2] A. J. Arko, J. J. Joyce, L. Morales, J. Wills, and J. Lashley et. al., Phys. Rev. B, 62, 1773 (2000). [3] B. R. Cooper et al, Phil. Mag. B 79, 683 (1999); B.R. Cooper, Los Alamos Science 26, 106 (2000)); B.R. Cooper, A.K. Setty and D.L.Price, to be published.

Functional analysis of two sterol regulatory element binding proteins in Penicillium digitatum

PubMed Central

Ruan, Ruoxin; Wang, Mingshuang; Liu, Xin; Sun, Xuepeng; Chung, Kuang-Ren

2017-01-01

The sterol regulatory element binding proteins (SREBPs) are key regulators for sterol homeostasis in most fungi. In the citrus postharvest pathogen Penicillium digitatum, the SREBP homolog is required for fungicide resistance and regulation of CYP51 expression. In this study, we identified another SREBP transcription factor PdSreB in P. digitatum, and the biological functions of both SREBPs were characterized and compared. Inactivation of PdsreA, PdsreB or both genes in P. digitatum reduced ergosterol contents and increased sensitivities to sterol 14-α-demethylation inhibitors (DMIs) and cobalt chloride. Fungal strains impaired at PdsreA but not PdsreB increased sensitivity to tridemorph and an iron chelator 2,2’-dipyridyl. Virulence assays on citrus fruit revealed that fungal strains impaired at PdsreA, PdsreB or both induce maceration lesions similar to those induced by wild-type. However, ΔPdsreA, ΔPdsreB or the double mutant strain rarely produce aerial mycelia on infected citrus fruit peels. RNA-Seq analysis showed the broad regulatory functions of both SREBPs in biosynthesis, transmembrane transportation and stress responses. Our results provide new insights into the conserved and differentiated regulatory functions of SREBP homologs in plant pathogenic fungi. PMID:28467453

Societal-Equity-Enhancing Criteria and Facility-Host Incentives Supporting Five Key Elements in the January 2012 Blue Ribbon Commission Report - 13015

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eriksson, Leif G.; Dials, George E.; George, Critz H.

2013-07-01

In February 2009, the Obama Administration announced it would abandon USA's only candidate SNF/HLW-disposal facility since 1987. In 2010, all related activities were stopped and the Blue Ribbon Commission on America's Nuclear Future was established 'to recommend a new strategy for managing the back end of the nuclear fuel cycle', which it did in January 2012, emphasizing eight key elements. However, Key Element 1, 'A new, consent-based approach to siting future nuclear facilities', is qualitative/indeterminate rather than quantitative/measurable. It is thus highly-susceptible to semantic permutations that could extend rather than, as intended, expedite the siting of future nuclear facilities unlessmore » it also defines: a) Whose consent is needed?; and b) What constitutes consent? The following 'generic', radiation-risk- and societal-equity-based criteria address these questions: 1. Identify areas affected by projected radiation and other health risks from: a. The proposed nuclear facility (facility stakeholders); and b. The related nuclear-materials-transportation routes (transportation stakeholders); then 2. Surround each stakeholder area with a buffer zone and use this enlarged foot print to identify: a. Stakeholder hosts; and b. Areas not hosting any stakeholder category (interested parties). 3. Define 'consent-based' as being at least 60 percent of the 'population' in the respective stakeholder category and apply this yardstick to both 'in favor' and 'against' votes. Although criteria 1 and 2 also need facility-based definitions to make Key Element 1 measurable, the described siting approach, augmented by related facility-host incentives, would expedite the schedule and reduce the cost for achieving Key Elements 4-6 and 8, politics permitting. (authors)« less

Ionization of Local Interstellar Gas Based on STIS and FUSE spectra of Nearby Stars

NASA Astrophysics Data System (ADS)

Redfield, Seth; Linsky, J. L.

2009-01-01

The ultraviolet contains many resonance line transitions that are sensitive to a range of ionization stages of ions present in the local interstellar medium (LISM). We couple observations of high resolution ultraviolet spectrographs, STIS and GHRS on the Hubble Space Telescope (HST) and the Far-Ultraviolet Spectroscopic Explorer (FUSE) in order to make a comprehensive survey of the ionization structure of the local interstellar medium. In particular, we focus on the sight line toward G191-B2B, a nearby (69 pc) white dwarf. We present interstellar detections of highly ionized elements (e.g., SiIII, CIII, CIV, etc) and compare them directly to neutral or singly ionized LISM detections (e.g., SiII, CII, etc). The extensive observations of G191-B2B provides an opportunity for a broad study of ionization stages of several elements, while a survey of several sight lines provides a comprehensive look at the ionization structure of the LISM. We acknowledge support for this project through NASA FUSE Grant NNX06AD33G.

Os, Nd and Sr isotope and trace element geochemistry of the Muli picrites: Insights into the mantle source of the Emeishan Large Igneous Province

NASA Astrophysics Data System (ADS)

Li, Jie; Xu, Ji-Feng; Suzuki, Katsuhiko; He, Bin; Xu, Yi-Gang; Ren, Zhong-Yuan

2010-09-01

A suite of picrites and basalts from the Muli area, in the northwestern part of the Emeishan continental flood basalt province, provides new and valuable information on the geochemistry of the Emeishan Large Igneous Province (LIP) and its source. The Muli picrites can be classified as type-1 or type-2. The former shows ocean-island basalt-like trace element characteristics, with γ Os (260 Ma) values and ɛ Nd (260 Ma) values ranging from + 7.5 to + 11.5 and from + 6.0 to + 7.8, respectively. This is the first time that picrites with highly radiogenic Os and high Os contents (up to 3.3 ppb) have been recognized in the Emeishan LIP. These characteristics probably reflect a relatively enriched component in the Emeishan LIP source. The type-2 picrites are characterized by non-radiogenic γ Os (260 Ma) values ranging from - 4.2 to - 0.3, and they may be further subdivided into type-2A and type-2B picrites. Type-2A picrites contain moderate amounts of the light rare earth elements (LREEs), have low Ce N/Yb N values (1.1-2.0), and a relatively high initial ɛ Nd (+ 5.0 to + 6.6). In terms of Os and Nd isotopes, the Muli type-2A picrites are similar to the Song Da komatiites of Vietnam and the Gorgona Island picrites, revealing the existence of a depleted mantle component in the Emeishan LIP source. In contrast with the type-2A picrites, type-2B lavas exhibit a negative Nb anomaly and relatively lower initial ɛ Nd and γ Os values (Nb/La > 1.8; ɛ Nd (260 Ma) = - 5.5 to + 6.4; γ Os (260 Ma) = - 4.2 to - 1.9), suggesting that the type-2B lavas have a depleted mantle source, similar to type-2A, but that the type-2B lavas are also influenced by various degrees of mixing of depleted plume-derived melt, sub-continental lithospheric mantle, and/or continental crust. Given that the basalts in the Muli area show similar geochemical features to those of the type-2B picrites, their origins are inferred to be similar.

Determining baseline element composition of lichens. I. Parmelia sulcata at Theodore Roosevelt national park, North Dakota

USGS Publications Warehouse

Gough, L.P.; Severson, R.C.; Jackson, L.L.

1988-01-01

Element-concentration baselines are given for Parmelia sulcata and associated soils. Parmelia chlorochroa was found sporadically and therefore only representative concentration ranges are reported for this species. Element data include (1) for lichens; Al, As, Ba, B, Ca, Cr, Cu, Fe, Hg, Mn, Ni, P, Sr, S, Ti, V, Y, and Zn; and (2) for soils: Al, Ba, Be, Ca, Cs, Cr, Cu, Fe, Hg, Mg, Mn, Ni, Nb, P, Pb, Sr, S, Ti, V, Y, and Zn. Very little (usually 7.2 km); thus, P sulcata is, in general, chemically similar throughout the park. This same uniformity was found for soil geochemistry. Numerous samples collected at close intervals would be required, therefore, to produce detailed element-concentration maps for P. sulcata and soils. No instances of elemental phytotoxic conditions were found; however, P. sulcata apparently possesses large concentrations of Ba, Cu, Fe, Pb, S, V, and possibly Zn.

FUSE Observations of He-rich sdB Stars

NASA Technical Reports Server (NTRS)

Swiegart, A. V.; Lanz, T.; Brown, T. M.; Hubeny, I.; Landsman, W. B.

2003-01-01

Most subdwarf B stars are extremely deficient in helium and selected light elements, but a minority are helium-rich. New evolutionary calculations suggest that these helium-rich sdB stars are the result of a delayed helium-core flash on the white dwarf cooling curve, which leads to extensive mixing between the hydrogen envelope and helium core. Such mixed stars should show greatly enhanced helium and carbon with respect to the other heavy elements. We have recently obtained FUSE spectra of two helium-rich sdB stars, PG1544+488 and JL87, revealing huge C Ill lines at 977 and 1176 A. Our analysis shows that PG1544+488 has a surface composition of 97% He, 2% C, and 1% N, in agreement with the new evolutionary scenario. While JL87 also reveals a large enrichment in carbon and nitrogen (1.4% and 0.4%, respectively), there is still a significant amount of hydrogen in its atmosphere.

OptSSeq: High-throughput sequencing readout of growth enrichment defines optimal gene expression elements for homoethanologenesis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ghosh, Indro Neil; Landick, Robert

The optimization of synthetic pathways is a central challenge in metabolic engineering. OptSSeq (Optimization by Selection and Sequencing) is one approach to this challenge. OptSSeq couples selection of optimal enzyme expression levels linked to cell growth rate with high-throughput sequencing to track enrichment of gene expression elements (promoters and ribosomebinding sites) from a combinatorial library. OptSSeq yields information on both optimal and suboptimal enzyme levels, and helps identify constraints that limit maximal product formation. Here we report a proof-of-concept implementation of OptSSeq using homoethanologenesis, a two-step pathway consisting of pyruvate decarboxylase (Pdc) and alcohol dehydrogenase (Adh) that converts pyruvate tomore » ethanol and is naturally optimized in the bacterium Zymomonas mobilis. We used OptSSeq to determine optimal gene expression elements and enzyme levels for Z. mobilis Pdc, AdhA, and AdhB expressed in Escherichia coli. By varying both expression signals and gene order, we identified an optimal solution using only Pdc and AdhB. We resolved current uncertainty about the functions of the Fe 2+-dependent AdhB and Zn 2+- dependent AdhA by showing that AdhB is preferred over AdhA for rapid growth in both E. coli and Z. mobilis. Finally, by comparing predictions of growth-linked metabolic flux to enzyme synthesis costs, we established that optimal E. coli homoethanologenesis was achieved by our best pdc-adhB expression cassette and that the remaining constraints lie in the E. coli metabolic network or inefficient Pdc or AdhB function in E. coli. Furthermore, OptSSeq is a general tool for synthetic biology to tune enzyme levels in any pathway whose optimal function can be linked to cell growth or survival.« less

OptSSeq: High-throughput sequencing readout of growth enrichment defines optimal gene expression elements for homoethanologenesis

DOE PAGES

Ghosh, Indro Neil; Landick, Robert

2016-07-16

The optimization of synthetic pathways is a central challenge in metabolic engineering. OptSSeq (Optimization by Selection and Sequencing) is one approach to this challenge. OptSSeq couples selection of optimal enzyme expression levels linked to cell growth rate with high-throughput sequencing to track enrichment of gene expression elements (promoters and ribosomebinding sites) from a combinatorial library. OptSSeq yields information on both optimal and suboptimal enzyme levels, and helps identify constraints that limit maximal product formation. Here we report a proof-of-concept implementation of OptSSeq using homoethanologenesis, a two-step pathway consisting of pyruvate decarboxylase (Pdc) and alcohol dehydrogenase (Adh) that converts pyruvate tomore » ethanol and is naturally optimized in the bacterium Zymomonas mobilis. We used OptSSeq to determine optimal gene expression elements and enzyme levels for Z. mobilis Pdc, AdhA, and AdhB expressed in Escherichia coli. By varying both expression signals and gene order, we identified an optimal solution using only Pdc and AdhB. We resolved current uncertainty about the functions of the Fe 2+-dependent AdhB and Zn 2+- dependent AdhA by showing that AdhB is preferred over AdhA for rapid growth in both E. coli and Z. mobilis. Finally, by comparing predictions of growth-linked metabolic flux to enzyme synthesis costs, we established that optimal E. coli homoethanologenesis was achieved by our best pdc-adhB expression cassette and that the remaining constraints lie in the E. coli metabolic network or inefficient Pdc or AdhB function in E. coli. Furthermore, OptSSeq is a general tool for synthetic biology to tune enzyme levels in any pathway whose optimal function can be linked to cell growth or survival.« less

Incorporation of Mg, Sr, Ba, U, and B in High-Mg Calcite Benthic Foraminifers Cultured Under Controlled pCO2

NASA Astrophysics Data System (ADS)

Not, C.; Thibodeau, B.; Yokoyama, Y.

2018-01-01

Measurement of elemental ratios (E/Ca) has been performed in two symbiont-bearing species of high-Mg calcite benthic foraminifers (hyaline, Baculogypsina sphaerulata and porcelaneous, Amphisorus hemprichii), cultured under five pCO2 levels, representing preindustrial, modern, and three predicted future values. E/Ca ratios were analyzed by Laser Ablation coupled with Inductively Coupled Plasma Mass Spectrometer (LA-ICP-MS). We measured several E/Ca, such as Mg/Ca, Sr/Ca, Ba/Ca, U/Ca, and B/Ca simultaneously. We observed that high-Mg calcite benthic foraminifers possess higher E/Ca than low-Mg calcite foraminifers, irrespective of their calcification mode (hyaline or porcelaneous). In both modes of calcification, Mg, Sr, Ba, U, and B incorporation could be controlled by Rayleigh fractionation. However, more data are needed to validate and quantify the relative importance of this process and closely investigate the presence/absence of other mechanism. Therefore, it highlights the need for a multielemental approach when looking at trace element incorporation. Finally, no significant relationship was observed between the different ratios and the pCO2 of the water, suggesting that none of the Mg/Ca, Sr/Ca, Ba/Ca, U/Ca, and B/Ca is sensitive to bottom water pCO2 or pH for these species.

The food choice at work study: effectiveness of complex workplace dietary interventions on dietary behaviours and diet-related disease risk - study protocol for a clustered controlled trial

PubMed Central

2013-01-01

Background Dietary behaviour interventions have the potential to reduce diet-related disease. Ample opportunity exists to implement these interventions in the workplace. The overall aim is to assess the effectiveness and cost-effectiveness of complex dietary interventions focused on environmental dietary modification alone or in combination with nutrition education in large manufacturing workplace settings. Methods/design A clustered controlled trial involving four large multinational manufacturing workplaces in Cork will be conducted. The complex intervention design has been developed using the Medical Research Council’s framework and the National Institute for Health and Clinical Excellence (NICE) guidelines and will be reported using the TREND statement for the transparent reporting of evaluations with non-randomized designs. It will draw on a soft paternalistic “nudge” theoretical perspective. Nutrition education will include three elements: group presentations, individual nutrition consultations and detailed nutrition information. Environmental dietary modification will consist of five elements: (a) restriction of fat, saturated fat, sugar and salt, (b) increase in fibre, fruit and vegetables, (c) price discounts for whole fresh fruit, (d) strategic positioning of healthier alternatives and (e) portion size control. No intervention will be offered in workplace A (control). Workplace B will receive nutrition education. Workplace C will receive nutrition education and environmental dietary modification. Workplace D will receive environmental dietary modification alone. A total of 448 participants aged 18 to 64 years will be selected randomly. All permanent, full-time employees, purchasing at least one main meal in the workplace daily, will be eligible. Changes in dietary behaviours, nutrition knowledge, health status with measurements obtained at baseline and at intervals of 3 to 4 months, 7 to 9 months and 13 to 16 months will be recorded. A process evaluation and cost-effectiveness economic evaluation will be undertaken. Discussion A 'Food Choice at Work’ toolbox (concise teaching kit to replicate the intervention) will be developed to inform and guide future researchers, workplace stakeholders, policy makers and the food industry. Trial registration Current Controlled Trials, ISRCTN35108237 PMID:24192134

The food choice at work study: effectiveness of complex workplace dietary interventions on dietary behaviours and diet-related disease risk - study protocol for a clustered controlled trial.

PubMed

Geaney, Fiona; Scotto Di Marrazzo, Jessica; Kelly, Clare; Fitzgerald, Anthony P; Harrington, Janas M; Kirby, Ann; McKenzie, Ken; Greiner, Birgit; Perry, Ivan J

2013-11-06

Dietary behaviour interventions have the potential to reduce diet-related disease. Ample opportunity exists to implement these interventions in the workplace. The overall aim is to assess the effectiveness and cost-effectiveness of complex dietary interventions focused on environmental dietary modification alone or in combination with nutrition education in large manufacturing workplace settings. A clustered controlled trial involving four large multinational manufacturing workplaces in Cork will be conducted. The complex intervention design has been developed using the Medical Research Council's framework and the National Institute for Health and Clinical Excellence (NICE) guidelines and will be reported using the TREND statement for the transparent reporting of evaluations with non-randomized designs. It will draw on a soft paternalistic 'nudge' theoretical perspective. It will draw on a soft paternalistic "nudge" theoretical perspective. Nutrition education will include three elements: group presentations, individual nutrition consultations and detailed nutrition information. Environmental dietary modification will consist of five elements: (a) restriction of fat, saturated fat, sugar and salt, (b) increase in fibre, fruit and vegetables, (c) price discounts for whole fresh fruit, (d) strategic positioning of healthier alternatives and (e) portion size control. No intervention will be offered in workplace A (control). Workplace B will receive nutrition education. Workplace C will receive nutrition education and environmental dietary modification. Workplace D will receive environmental dietary modification alone. A total of 448 participants aged 18 to 64 years will be selected randomly. All permanent, full-time employees, purchasing at least one main meal in the workplace daily, will be eligible. Changes in dietary behaviours, nutrition knowledge, health status with measurements obtained at baseline and at intervals of 3 to 4 months, 7 to 9 months and 13 to 16 months will be recorded. A process evaluation and cost-effectiveness economic evaluation will be undertaken. A 'Food Choice at Work' toolbox (concise teaching kit to replicate the intervention) will be developed to inform and guide future researchers, workplace stakeholders, policy makers and the food industry. Current Controlled Trials, ISRCTN35108237.

In search of the elusive IrB{sub 2}: Can mechanochemistry help?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xie, Zhilin; Blair, Richard G.; Department of Physics, University of Central Florida, Orlando, FL 32816

The previously unknown hexagonal ReB{sub 2}-type IrB{sub 2} diboride and orthorhombic IrB monoboride phases were produced by mechanochemical syntheses. High energy ball milling of elemental Ir and B powder for 30 h, followed by annealing of the powder at 1050 °C for 48 h, resulted in the formation of the desired phases. Both traditional laboratory and high resolution synchrotron X-ray diffraction (XRD) analyses were used for phase identification of the synthesized powder. In addition to XRD, scanning electron microscopy and transmission electron microscopy were employed to further characterize the microstructure of the phases produced. - Graphical abstract: ReB{sub 2}-type IrB{submore » 2} and a new IrB have been successfully synthesized for the first time using mechanochemical method. Crystal structures of IrB{sub 2} and IrB were studied by synchrotron X-ray diffraction. Microstructures of the new phases were characterized by SEM and TEM. - Highlights: • ReB{sub 2}-type IrB{sub 2} and a new IrB have been synthesized by mechanochemical method. • Crystal structures of IrB{sub 2} and IrB were studied by synchrotron XRD. • Microstructures of the new phases were characterized by SEM and TEM.« less

The Joint Astrophysical Plasmadynamic Experiment (J-PEX): a high-resolution rocket spectrometer

NASA Astrophysics Data System (ADS)

Barstow, Martin A.; Bannister, Nigel P.; Cruddace, Raymond G.; Kowalski, Michael P.; Wood, Kent S.; Yentis, Daryl J.; Gursky, Herbert; Barbee, Troy W., Jr.; Goldstein, William H.; Kordas, Joseph F.; Fritz, Gilbert G.; Culhane, J. Leonard; Lapington, Jonathan S.

2003-02-01

We report on the successful sounding rocket flight of the high resolution (R=3000-4000) J-PEX EUV spectrometer. J-PEX is a novel normal incidence instrument, which combines the focusing and dispersive elements of the spectrometer into a single optical element, a multilayer-coated grating. The high spectral resolution achieved has had to be matched by unprecedented high spatial resolution in the imaging microchannel plate detector used to record the data. We illustrate the performance of the complete instrument through an analysis of the 220-245Å spectrum of the white dwarf G191-B2B obtained with a 300 second exposure. The high resolution allows us to detect a low-density ionized helium component along the line of sight to the star and individual absorption lines from heavier elements in the photosphere.

Adhesive and Cohesive Strength in FeB/Fe2B Systems

NASA Astrophysics Data System (ADS)

Meneses-Amador, A.; Blancas-Pérez, D.; Corpus-Mejía, R.; Rodríguez-Castro, G. A.; Martínez-Trinidad, J.; Jiménez-Tinoco, L. F.

2018-05-01

In this work, FeB/Fe2B systems were evaluated by the scratch test. The powder-pack boriding process was performed on the surface of AISI M2 steel. The mechanical parameters, such as yield stress and Young's modulus of the boride layer, were obtained by the instrumented indentation technique. Residual stresses produced on the boride layer were estimated by using the x-ray diffraction (XRD) technique. The scratch test was performed in order to evaluate the cohesive/adhesive strength of the FeB/Fe2B coating. In addition, a numerical evaluation of the scratch test on boride layers was performed by the finite element method. Maximum principal stresses were related to the failure mechanisms observed by the experimental scratch test. Shear stresses at the interfaces of the FeB/Fe2B/substrate system were also evaluated. Finally, the results obtained provide essential information about the effect of the layer thickness, the residual stresses, and the resilience modulus on the cohesive/adhesive strength in FeB/Fe2B systems.

A High-Frequency Linear Ultrasonic Array Utilizing an Interdigitally Bonded 2-2 Piezo-Composite

PubMed Central

Cannata, Jonathan M.; Williams, Jay A.; Zhang, Lequan; Hu, Chang-Hong; Shung, K. Kirk

2011-01-01

This paper describes the development of a high-frequency 256-element linear ultrasonic array utilizing an interdigitally bonded (IB) piezo-composite. Several IB composites were fabricated with different commercial and experimental piezoelectric ceramics and evaluated to determine a suitable formulation for use in high-frequency linear arrays. It was found that the fabricated fine-scale 2–2 IB composites outperformed 1–3 IB composites with identical pillar- and kerf-widths. This result was not expected and lead to the conclusion that dicing damage was likely the cause of the discrepancy. Ultimately, a 2–2 composite fabricated using a fine-grain piezoelectric ceramic was chosen for the array. The composite was manufactured using one IB operation in the azimuth direction to produce approximately 19-μm-wide pillars separated by 6-μm-wide kerfs. The array had a 50 μm (one wavelength in water) azimuth pitch, two matching layers, and 2 mm elevation length focused to 7.3 mm using a polymethylpentene (TPX) lens. The measured pulse-echo center frequency for a representative array element was 28 MHz and −6-dB band-width was 61%. The measured single-element transmit −6-dB directivity was estimated to be 50°. The measured insertion loss was 19 dB after compensating for the effects of attenuation and diffraction in the water bath. A fine-wire phantom was used to assess the lateral and axial resolution of the array when paired with a prototype system utilizing a 64-channel analog beamformer. The −6-dB lateral and axial resolutions were estimated to be 125 and 68 μm, respectively. An anechoic cyst phantom was also imaged to determine the minimum detectable spherical inclusion, and thus the 3-D resolution of the array and beamformer. The minimum anechoic cyst detected was approximately 300 μm in diameter. PMID:21989884

Engaging Elements of Cancer-Related Digital Stories in Alaska

PubMed Central

Cueva, Melany; Kuhnley, Regina; Revels, Laura; Schoenberg, Nancy E.; Lanier, Anne; Dignan, Mark

2015-01-01

The tradition of storytelling is an integral part of Alaska Native cultures that continues to be a way of passing on knowledge. Using a story-based approach to share cancer education is grounded in Alaska Native traditions and people’s experiences and has the potential to positively impact cancer knowledge, understandings, and wellness choices. Community health workers (CHWs) in Alaska created a personal digital story as part of a 5-day, in-person cancer education course. To identify engaging elements of digital stories among Alaska Native people, one focus group was held in each of three different Alaska communities with a total of 29 adult participants. After viewing CHWs’ digital stories created during CHW cancer education courses, focus group participants commented verbally and in writing about cultural relevance, engaging elements, information learned, and intent to change health behavior. Digital stories were described by Alaska focus group participants as being culturally respectful, informational, inspiring, and motivational. Viewers shared that they liked digital stories because they were short (only 2–3 min); nondirective and not preachy; emotional, told as a personal story and not just facts and figures; and relevant, using photos that showed Alaskan places and people. PMID:25865400

Engaging Elements of Cancer-Related Digital Stories in Alaska.

PubMed

Cueva, Melany; Kuhnley, Regina; Revels, Laura; Schoenberg, Nancy E; Lanier, Anne; Dignan, Mark

2016-09-01

The tradition of storytelling is an integral part of Alaska Native cultures that continues to be a way of passing on knowledge. Using a story-based approach to share cancer education is grounded in Alaska Native traditions and people's experiences and has the potential to positively impact cancer knowledge, understandings, and wellness choices. Community health workers (CHWs) in Alaska created a personal digital story as part of a 5-day, in-person cancer education course. To identify engaging elements of digital stories among Alaska Native people, one focus group was held in each of three different Alaska communities with a total of 29 adult participants. After viewing CHWs' digital stories created during CHW cancer education courses, focus group participants commented verbally and in writing about cultural relevance, engaging elements, information learned, and intent to change health behavior. Digital stories were described by Alaska focus group participants as being culturally respectful, informational, inspiring, and motivational. Viewers shared that they liked digital stories because they were short (only 2-3 min); nondirective and not preachy; emotional, told as a personal story and not just facts and figures; and relevant, using photos that showed Alaskan places and people.

Peace Education: Exploring Some Philosophical Foundations

NASA Astrophysics Data System (ADS)

Page, James S.

2004-01-01

Peace education has been recognized as an important aspect of social education for the past three decades. The critical literature as well as official documents, however, have given little attention to its philosophical foundations. This essay explores these foundations in the ethics of (1) virtue, (2) consequentialism, (3) aesthetics, (4) conservative politics and (5) care. Each of these alone composes a significant element of peace education, although ultimately its solid basis can only be established through an integrative approach encouraging a culture of peace. The more complete development and articulation of the philosophical rationale of peace education is yet to be accomplished and remains a task for the future.

[Influence of zeolite A supplementation during the dry period of dairy cows on feed intake, on the macro and trace element metabolism around calving and milk yield in the following lactation].

PubMed

Grabherr, Hilde; Spolders, Markus; Flachowsky, Gerhard; Fürll, Manfred

2008-01-01

The object of the present study was to determine the influence of zeolite A, a calcium binder from the group of the aluminosilicate, on feed intake, macro and trace element metabolism as well as the milk yield in the following lactation in dairy cows. 46 cows were allotted to 2 groups (A--control group and B--experimental group). They were fed a total mixed ration (TMR) ad libitum 2 weeks before calving. Additionally the cows in group B received 90 g zeolite A/kg dry matter (DM). The individually feed intake was registered daily. The serum was analysed for Ca, Mg, and Pi (inorganic phosphate), Fe, FFA (free fatty acid) and beta-HB (hydroxybutyrate) and the plasma for the trace elements Cu, Zn, and Mn. After calving the milk yield (FCM) and the milk composition (fat, protein, lactose and urea) were analysed. Feed intake of group B, amounting to 6.2 +/- 1.3 kg DM/d was around 48% lower as compared to 12.0 +/- 1.4 kg DM/d for group A. The zeolite addition into the TMR showed a stabilizing effect on the average Ca concentration in the serum around calving. This effect led to a significantly lower Mg concentration on the day of calving and 1 day post partum. The Pi concentration was significantly lower already after the 1st week of zeolite supplementation and on the day of calving as compared to group A. There was no essential effect of zeolite A on the trace element concentration. The depression of feed intake for group B led to a significant increase of FFA one week after beginning zeolite supplementation and of beta-HB around calving. The feed intake post partum as well as the milk yield were not affected by zeolite supplementation. Because decreased feed intake of group B after zeolite supplementation and the occurred hypophosphatemia, it is not acceptable to use zeolite A in the proved dose for preventing milk fever.

Examining the Role of Multicultural Competence in Leadership Program Design

ERIC Educational Resources Information Center

Wilson, Amy B.

2015-01-01

Research examining the multicultural competence of leadership educators across a variety of institutions demonstrated variance based on leadership program structure, program elements, and the ways in which diversity was addressed in the program. The Multicultural Competence in Student Affairs-Preliminary 2 (MCSA-P2) scale was used to measure…

Constructive Conflict Talk in Classrooms: Divergent Approaches to Addressing Divergent Perspectives

ERIC Educational Resources Information Center

Bickmore, Kathy; Parker, Christina

2014-01-01

Dialogue about social and political conflicts is a key element of democratic citizenship education that is frequently advocated in scholarship but rarely fully implemented, especially in classrooms populated by ethnically and economically heterogeneous students. Qualitative case studies describe the contrasting ways 2 primary and 2 middle-grade…

Phase stable rare earth garnets

DOEpatents

Kuntz, Joshua D.; Cherepy, Nerine J.; Roberts, Jeffery J.; Payne, Stephen A.

2013-06-11

A transparent ceramic according to one embodiment includes a rare earth garnet comprising A.sub.hB.sub.iC.sub.jO.sub.12, where h is 3.+-.10%, i is 2.+-.10%, and j is 3.+-.10%. A includes a rare earth element or a mixture of rare earth elements, B includes at least one of aluminum, gallium and scandium, and C includes at least one of aluminum, gallium and scandium, where A is at a dodecahedral site of the garnet, B is at an octahedral site of the garnet, and C is at a tetrahedral site of the garnet. In one embodiment, the rare earth garment has scintillation properties. A radiation detector in one embodiment includes a transparent ceramic as described above and a photo detector optically coupled to the rare earth garnet.

38 CFR 21.6210 - Supplies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... REHABILITATION AND EDUCATION Temporary Program of Vocational Training for Certain New Pension Recipients Supplies...: 38 U.S.C. 1524(b)(2)) (b) Definition. The term supplies includes books, tools and other supplies and... discontinued from an independent living services program. (Authority: 38 U.S.C. 1524(b)(2)) Medical and Related...

38 CFR 21.6210 - Supplies.

Code of Federal Regulations, 2011 CFR

2011-07-01

... REHABILITATION AND EDUCATION Temporary Program of Vocational Training for Certain New Pension Recipients Supplies...: 38 U.S.C. 1524(b)(2)) (b) Definition. The term supplies includes books, tools and other supplies and... discontinued from an independent living services program. (Authority: 38 U.S.C. 1524(b)(2)) Medical and Related...

Methodology Plan for Minimum Resolvable Temperature Difference (MRTD) Testing of Aircraft Installed Sensors

DTIC Science & Technology

2011-03-23

sensors (e.g., sensor fusion) or use different detector materials to increase spectral bands into the Near IR (NIR). 3. Holst2provides an...a. Detector type: Multi-element MCT SPRITE b. Wavelength: Long wave, 8-12 um c. Cooling system: Integrated Sterling cooler d. Cooldown...A-1 B. COLLIMATOR SYSTEM DESIGN AND EO/ IR TOPICS ................ B-1 C. ATTC FACILITIES AND INSTRUMENTATION

Trust and Decision Making: An Empirical Platform

DTIC Science & Technology

2008-06-01

13th ICCRTS “C2 for Complex Endeavors” Trust and Decision Making : An Empirical Platform Topic(s): Cognitive and Social Issues...and Decision Making : An Empirical Platform 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e...PERSON a. REPORT unclassified b. ABSTRACT unclassified c. THIS PAGE unclassified Trust and Decision Making : An Empirical Platform Dr. Joseph B

41 CFR 101-4.415 - Access to course offerings.

Code of Federal Regulations, 2010 CFR

2010-07-01

... basis, including health, physical education, industrial, business, vocational, technical, home economics, music, and adult education courses. (b)(1) With respect to classes and activities in physical education... September 29, 2000. (2) This section does not prohibit grouping of students in physical education classes...

Structural Determinants of Substrate Recognition in the HAD Superfamily Member D-glycero-D-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nguyen, H.; Wang, L; Huang, H

2010-01-01

The haloalkanoic acid dehalogenase (HAD) enzyme superfamily is the largest family of phosphohydrolases. In HAD members, the structural elements that provide the binding interactions that support substrate specificity are separated from those that orchestrate catalysis. For most HAD phosphatases, a cap domain functions in substrate recognition. However, for the HAD phosphatases that lack a cap domain, an alternate strategy for substrate selection must be operative. One such HAD phosphatase, GmhB of the HisB subfamily, was selected for structure-function analysis. Herein, the X-ray crystallographic structures of Escherichia coli GmhB in the apo form (1.6 {angstrom} resolution), in a complex with Mg{supmore » 2+} and orthophosphate (1.8 {angstrom} resolution), and in a complex with Mg{sup 2+} and D-glycero-D-manno-heptose 1{beta},7-bisphosphate (2.2 {angstrom} resolution) were determined, in addition to the structure of Bordetella bronchiseptica GmhB bound to Mg{sup 2+} and orthophosphate (1.7 {angstrom} resolution). The structures show that in place of a cap domain, the GmhB catalytic site is elaborated by three peptide inserts or loops that pack to form a concave, semicircular surface around the substrate leaving group. Structure-guided kinetic analysis of site-directed mutants was conducted in parallel with a bioinformatics study of sequence diversification within the HisB subfamily to identify loop residues that serve as substrate recognition elements and that distinguish GmhB from its subfamily counterpart, the histidinol-phosphate phosphatase domain of HisB. We show that GmhB and the histidinol-phosphate phosphatase domain use the same design of three substrate recognition loops inserted into the cap domain yet, through selective residue usage on the loops, have achieved unique substrate specificity and thus novel biochemical function.« less

[Study on the determination of 28 inorganic elements in sunflower seeds by ICP-OES/ICP-MS].

PubMed

Liu, Hong-Wei; Qin, Zong-Hui; Xie, Hua-Lin; Cao, Shu

2013-01-01

The present paper describes a simple method for the determination of trace elements in sunflower seeds by using inductively coupled plasma optical emission spectrometry (ICP-OES) and inductively coupled plasma spectrometry (ICP-MS). HNO3 + H2O2 were used to achieve the complete decomposition of the organic matrix in a closed-vessel microwave oven. The contents of 10 trace elements (Al, B, Ca, Fe, K, Mg, Na, Si, P and S) in sunflower seeds were determined by ICP-OES while 18 trace elements (As, Ba, Cd, Co, Cr, Cu, Li, Mn, Mo, Ni, Pb, Rb, Sr, Sn, Sb, Ti, V and Zn) were determined by ICP-MS. The rice reference material (GBW10045) was used as standard reference materials. The results showed a good agreement between measured and certified values for all analytes. The concentrations of necessary micro elements Ca, K, Mg, P and S were higher. This method was simple, sensitive and precise and can perform simultaneous multi-elements determination of sunflower seeds.

Interstellar Molecules in K-12 Education

NASA Astrophysics Data System (ADS)

Kuiper, T. B. H.; Hofstadter, M. D.; Levin, S. M.; MacLaren, D.

2006-12-01

The Lewis Center for Educational Research (LCER) and the Jet Propulsion Laboratory (JPL) collaborate in a K-12 educational project in which students conduct observations for several research programs led by radio astronomers. The Goldstone-Apple Valley Radio Telescope (GAVRT) program provides participating teachers with curriculum elements, based on the students' observing experiences, which support national and state academic standards. The current program is based on 2.2-GHz and 8.4-GHz radiometric observations of variable sources. The research programs monitor Jupiter, Uranus, and a selected set of quasars. The telescope is a decommissioned NASA Deep Space Network antenna at Goldstone, California. In the next three years, a second telescope will be added. This telescope will at least operate at the above frequencies as well as 6 GHz and 12 GHz. Possibly, it will operate in a continuous band from 1.2 GHz to 14 GHz. In either case, the telescope will be able to observe at least the 6.6-GHz and 12.2-GHz methanol maser lines. The success of the GAVRT program depends critically on the participation of scientists committed to the research who have the ability and enthusiasm for interacting with K-12 students, typically through teleconferences. The scientists will initially work with the LCER staff to create curriculum elements around their observing program.

Content of nutritional elements in sudangrass and ryegrass determined by ICP-AES.

PubMed

Li, Wen-Xi; Lu, Jian-Wei; Seneweera, Saman P; Wu, Ji; Chen, Fang; Lu, Jun-Ming; Li, Xiao-Kun

2011-09-01

The sudangrass (Sorghum sudanense) and ryegrass (Lolium multi florum L.) rotation is a new type of cropping system, which has developed rapidly in recent years in the south of China. The contents of nutritional elements for forage grass in the sudangrass and ryegrass rotation system were determined by ICP-AES. The results showed that there were abundant and essential nutritional elements for animals in sudangrass and ryegrass. The contents of P, K, Ca, Mg, S, Fe, B, Cu, Zn and Mn for sudangrass were 0.20% -0.29%, 1.94%-2.57%, 0.62%-0.97%, 0.39%-0.69%, 0.12%-0.18%, 108.35-180.12, 3.04-5.96, 6.17-10.02, 20.37-31.36 and 46.80-101.29 mg x kg(-1), respectively. The contents of P, K, Ca, Mg, S, Fe, B, Cu, Zn, Mn for ryegrass were 0.39%-0.70%, 3.77%-5.07%, 0.61%-0.84%, 0.28% -0.47%, 0.32%-0.41%, 291.65- 632.20, 2.13-3.23, 13.29-15.19, 30.73-42.98 and 92.08-156.04 mg x kg(-1), respectively, and there were differences between various periods in nutritional elements in the two forage grasses. The application of ICP-AES could reflect fast and efficiently the content of nutritional elements for forage grass as animals feed.

Perovskite phase thin films and method of making

DOEpatents

Boyle, Timothy J.; Rodriguez, Mark A.

2000-01-01

The present invention comprises perovskite-phase thin films, of the general formula A.sub.x B.sub.y O.sub.3 on a substrate, wherein A is selected from beryllium, magnesium, calcium, strontium, and barium or a combination thereof; B is selected from niobium and tantalum or a combination thereof; and x and y are mole fractions between approximately 0.8 and 1.2. More particularly, A is strontium or barium or a combination thereof and B is niobium or tantalum or a combination thereof. Also provided is a method of making a perovskite-phase thin film, comprising combining at least one element-A-containing compound, wherein A is selected from beryllium, magnesium, calcium, strontium or barium, with at least one element-B-containing compound, wherein B niobium or tantalum, to form a solution; adding a solvent to said solution to form another solution; spin-coating the solution onto a substrate to form a thin film; and heating the film to form the perovskite-phase thin film.

[Dynamic analysis of mineral elements during growth and development stage of the Kirilowii plant].

PubMed

Ma, Zhao; Wei, Min; Cui, Xu-Sheng; Guo, Yu-Hai

2013-03-01

ICP-AES technology was used to determine the major mineral elements content and analyze the dynamic and cumulative amount of the main absorption during the growth and development stage of the Kinlowii organs plant. The result showed as follows: (1)The mineral elements were changing in the different stage. The highest mineral element accumulation of K, P, Ca, Mg, Fe, Mn, Zn, Cu and Mo occured in October, their values are 3,695.90, 445.88, 9,649.32, 2,652.10 mg per plant, 324,398.29, 40,188.65, 22,383.13, 36,054.58 and 61.95 microg per plant separately. But the highest value of B occured in September and the value was 8 690.97 microg per plant. (2) the distribution of mineral element in the kirilowii plant was not even, the contents of K and P were highest in kirilowii peel, they can reach 27.65 and 2.63 mg.g-1. The contents of Ca and Mg were highest in kirilowii leaves, they can reach 33.28 and 5.73 mg .g-1. The contents of Fe, Mn, B were highest in kirilowii roots, they can reach: 4,069.74, 127.73, 24.75 microg.g-1. The contents of Zn and Mo were highest in kirilowii seeds, they can reach 68. 61 and 1.07 microg.g-1. (3) the cumulation dynamic of mineral elements in kirilowii plant during the whole stages was S-type, and the plant showed rapid growth from the mid-July to mid-Spetember. The information of this study will supply a scientific data for the quality assessment and rational fertilization of kirilowii plant and harvestment.