Geo-spatial reporting for monitoring of household immunization coverage through mobile phones: Findings from a feasibility study.

PubMed

Kazi, A M; Ali, M; K, Ayub; Kalimuddin, H; Zubair, K; Kazi, A N; A, Artani; Ali, S A

2017-11-01

The addition of Global Positioning System (GPS) to a mobile phone makes it a very powerful tool for surveillance and monitoring coverage of health programs. This technology enables transfer of data directly into computer applications and cross-references to Geographic Information Systems (GIS) maps, which enhances assessment of coverage and trends. Utilization of these systems in low and middle income countries is currently limited, particularly for immunization coverage assessments and polio vaccination campaigns. We piloted the use of this system and discussed its potential to improve the efficiency of field-based health providers and health managers for monitoring of the immunization program. Using "30×7" WHO sampling technique, a survey of children less than five years of age was conducted in random clusters of Karachi, Pakistan in three high risk towns where a polio case was detected in 2011. Center point of the cluster was calculated by the application on the mobile. Data and location coordinates were collected through a mobile phone. This data was linked with an automated mHealth based monitoring system for monitoring of Supplementary Immunization Activities (SIAs) in Karachi. After each SIA, a visual report was generated according to the coordinates collected from the survey. A total of 3535 participants consented to answer to a baseline survey. We found that the mobile phones incorporated with GIS maps can improve efficiency of health providers through real-time reporting and replacing paper based questionnaire for collection of data at household level. Visual maps generated from the data and geospatial analysis can also give a better assessment of the immunization coverage and polio vaccination campaigns. The study supports a model system in resource constrained settings that allows routine capture of individual level data through GPS enabled mobile phone providing actionable information and geospatial maps to local public health managers, policy makers and study staff monitoring immunization coverage. Copyright © 2017 Elsevier B.V. All rights reserved.

Fabricated World Class: Global University League Tables, Status Differentiation and Myths of Global Competition

ERIC Educational Resources Information Center

David, Matthew

2016-01-01

UK media coverage of global university league tables shows systematic bias towards the Russell Group, although also highlighting tensions within its membership. Coverage positions UK "elite" institutions between US superiority and Asian ascent. Coverage claims that league table results warrant UK university funding reform. However,…

Multipoint Geospace Science in 3D: The Paired Ionosphere-Thermosphere Orbiters(PITO) Mission

NASA Technical Reports Server (NTRS)

Clemmons, J.; Walterscheid, R.; Nigg, D.; Judnick, D.; Lang, J.; Spann, J.

2010-01-01

The science enabled by the Paired Ionosphere-Thermosphere Orbiters (PITO) mission is described and discussed. PITO has been designed to provide the concurrent, three-dimensional, multipoint measurements needed to advance geospace science while staying within a stringent resource envelope. The mission utilizes a pair of orbiting vehicles in eccentric, high-inclination, coplanar orbits. The orbits have arguments of perigee that differ by 180 degrees and are phased such that one vehicle is at perigee (200 km) while the second is at apogee (2000 km). Half an orbit later, the vehicles switch positions. Three complementary types of measurements exploit this scenario: local, in-situ measurements on both satellites, two-dimensional imaging from the higher satellite, and vertical sounders. The main idea is that two-dimensional context information for the low-altitude measurements is obtained by the high altitude imagers, while information on the third dimension is provided by vertical profiling. Such an observation system is capable of providing elements of global coverage, regional coverage, and concurrent coverage in three dimensions. Science goals are presented, as are the results of a detailed implementation plan, including several trade studies on key elements of the mission. The conclusion is that the mission would enable significant new understanding of the ionosphere-thermosphere system within a resource envelope that is consistent with that of NASA's Medium Explorer (MIDEX) line of science missions.

Tracking Vaccination Teams During Polio Campaigns in Northern Nigeria by Use of Geographic Information System Technology: 2013–2015

PubMed Central

Touray, Kebba; Mkanda, Pascal; Tegegn, Sisay G.; Nsubuga, Peter; Erbeto, Tesfaye B.; Banda, Richard; Etsano, Andrew; Shuaib, Faisal; Vaz, Rui G.

2016-01-01

Introduction. Nigeria is among the 3 countries in which polio remains endemic. The country made significant efforts to reduce polio transmission but remains challenged by poor-quality campaigns and poor team performance in some areas. This article demonstrates the application of geographic information system technology to track vaccination teams to monitor settlement coverage, reduce the number of missed settlements, and improve team performance. Methods. In each local government area where tracking was conducted, global positioning system–enabled Android phones were given to each team on a daily basis and were used to record team tracks. These tracks were uploaded to a dashboard to show the level of coverage and identify areas missed by the teams. Results. From 2012 to June 2015, tracking covered 119 immunization days. A total of 1149 tracking activities were conducted. Of these, 681 (59%) were implemented in Kano state. There was an improvement in the geographic coverage of settlements and an overall reduction in the number of missed settlements. Conclusions. The tracking of vaccination teams provided significant feedback during polio campaigns and enabled supervisors to evaluate performance of vaccination teams. The reports supported other polio program activities, such as review of microplans and the deployment of other interventions, for increasing population immunity in northern Nigeria. PMID:26609004

Constellation Coverage Analysis

NASA Technical Reports Server (NTRS)

Lo, Martin W. (Compiler)

1997-01-01

The design of satellite constellations requires an understanding of the dynamic global coverage provided by the constellations. Even for a small constellation with a simple circular orbit propagator, the combinatorial nature of the analysis frequently renders the problem intractable. Particularly for the initial design phase where the orbital parameters are still fluid and undetermined, the coverage information is crucial to evaluate the performance of the constellation design. We have developed a fast and simple algorithm for determining the global constellation coverage dynamically using image processing techniques. This approach provides a fast, powerful and simple method for the analysis of global constellation coverage.

Satellite Imagery Analysis for Automated Global Food Security Forecasting

NASA Astrophysics Data System (ADS)

Moody, D.; Brumby, S. P.; Chartrand, R.; Keisler, R.; Mathis, M.; Beneke, C. M.; Nicholaeff, D.; Skillman, S.; Warren, M. S.; Poehnelt, J.

2017-12-01

The recent computing performance revolution has driven improvements in sensor, communication, and storage technology. Multi-decadal remote sensing datasets at the petabyte scale are now available in commercial clouds, with new satellite constellations generating petabytes/year of daily high-resolution global coverage imagery. Cloud computing and storage, combined with recent advances in machine learning, are enabling understanding of the world at a scale and at a level of detail never before feasible. We present results from an ongoing effort to develop satellite imagery analysis tools that aggregate temporal, spatial, and spectral information and that can scale with the high-rate and dimensionality of imagery being collected. We focus on the problem of monitoring food crop productivity across the Middle East and North Africa, and show how an analysis-ready, multi-sensor data platform enables quick prototyping of satellite imagery analysis algorithms, from land use/land cover classification and natural resource mapping, to yearly and monthly vegetative health change trends at the structural field level.

Soil Moisture Active Passive (SMAP) Data and Services at the NASA DAACs

NASA Astrophysics Data System (ADS)

Leon, A.; Allen, A. R.; Leslie, S. R.

2014-12-01

The NASA Soil Moisture Active Passive (SMAP) mission will provide a capability for global mapping of soil moisture and freeze/thaw state with unprecedented accuracy, resolution, and coverage. The SMAP instrument includes both a radiometer and a synthetic aperture radar (SAR) operating at the L-band (1.20-1.41 GHz) and will provide global coverage at the equator every 3 days. The SMAP mission will play a critical role in understanding the Earth's water and energy cycles, improving weather and climate forecasting, and developing disaster prediction and monitoring services. The NASA Distributed Active Archive Centers (DAACs) at the Alaska Satellite Facility (ASF) and the National Snow and Ice Data Center (NSIDC) will jointly distribute and support SMAP data products. The DAACs will draw upon their unique expertise - ASF with SAR data and NSIDC with cryospheric and remotely-sensed soil moisture data- as well as their shared technologies to provide synergistic data access and support for SMAP products. In an effort to educate and broaden the SMAP user community, we will present an overview of the SMAP data products as well as when they will be available at the DAACs. NASA DAACs play an integral role in enabling data discovery and usage through the value-adding services they provide. Through this presentation, we will also discuss the tools and services at the ASF and NSIDC DAACs and gain further insight into how the DAACs can enable the user community to seamlessly and effectively utilize SMAP data in their research and applications.

Modeling Global Biogenic Emission of Isoprene: Exploration of Model Drivers

NASA Technical Reports Server (NTRS)

Alexander, Susan E.; Potter, Christopher S.; Coughlan, Joseph C.; Klooster, Steven A.; Lerdau, Manuel T.; Chatfield, Robert B.; Peterson, David L. (Technical Monitor)

1996-01-01

Vegetation provides the major source of isoprene emission to the atmosphere. We present a modeling approach to estimate global biogenic isoprene emission. The isoprene flux model is linked to a process-based computer simulation model of biogenic trace-gas fluxes that operates on scales that link regional and global data sets and ecosystem nutrient transformations Isoprene emission estimates are determined from estimates of ecosystem specific biomass, emission factors, and algorithms based on light and temperature. Our approach differs from an existing modeling framework by including the process-based global model for terrestrial ecosystem production, satellite derived ecosystem classification, and isoprene emission measurements from a tropical deciduous forest. We explore the sensitivity of model estimates to input parameters. The resulting emission products from the global 1 degree x 1 degree coverage provided by the satellite datasets and the process model allow flux estimations across large spatial scales and enable direct linkage to atmospheric models of trace-gas transport and transformation.

Small Spacecraft Constellation Concept for Mars Atmospheric Radio Occultations

NASA Astrophysics Data System (ADS)

Asmar, S. W.; Mannucci, A. J.; Ao, C. O.; Kobayashi, M. M.; Lazio, J.; Marinan, A.; Massone, G.; McCandless, S. E.; Preston, R. A.; Seubert, J.; Williamson, W.

2017-12-01

First demonstrated in 1965 when Mariner IV flew by Mars and determined the salient features of its atmosphere, radio occultation experiments have been carried out on numerous planetary missions with great discoveries. These experiments utilize the now classic configuration of a signal from a single planetary spacecraft to Earth receiving stations, where the science data are acquired. The Earth science community advanced the technique to utilizing a constellation of spacecraft with the radio occultation links between the spacecraft, enabled by the infrastructure of the Global Positioning System. With the advent of small and less costly spacecraft, such as planetary CubeSats and other variations, such as the anticipated innovative Mars Cube One mission, crosslinks among small spacecraft can be used to study other planets in the near future. Advantages of this type of experiment include significantly greater geographical coverage, which could reach global coverage over a few weeks with a small number of spacecraft. Repeatability of the global coverage can lead to examining temperature-pressure profiles and ionospheric electron density profiles, on daily, seasonal, annual, or other time scales of interest. The higher signal-to-noise ratio for inter-satellite links, compared to a link to Earth, decreases the design demands on the instrumentation (smaller antennas and transmitters, etc.). After an actual Mars crosslink demonstration, this concept has been in development using Mars as a possible target. Scientific objectives, delivery methods, operational scenarios and end-to-end configuration have been documented. Science objectives include determining the state and variability of the lower Martian atmosphere, which has been an identified as a high priority objective by the Mars Exploration Program Analysis Group, particularly as it relates to entry, descent, and landing and ascent for future crewed and robotic missions. This paper will present the latest research on the proposed mission concept including the possible spatial and temporal coverage, resolution of observables, mission design and expected results.

Satellite Estimates of the Direct Radiative Forcing of Biomass Burning Aerosols Over South America and Africa

NASA Technical Reports Server (NTRS)

Christopher, Sundar A.; Wang, Min; Kliche, Donna V.; Berendes, Todd; Welch, Ronald M.; Yang, S.K.

1997-01-01

Atmospheric aerosol particles, both natural and anthropogenic are important to the earth's radiative balance. Therefore it is important to provide adequate validation information on the spatial, temporal and radiative properties of aerosols. This will enable us to predict realistic global estimates of aerosol radiative effects more confidently. The current study utilizes 66 AVHRR LAC (Local Area Coverage) and coincident Earth Radiation Budget Experiment (ERBE) images to characterize the fires, smoke and radiative forcings of biomass burning aerosols over four major ecosystems of South America.

The Europa Mission: Multiple Europa Flyby Trajectory Design Trades and Challenges

NASA Technical Reports Server (NTRS)

Lam, Try; Arrieta-Camacho, Juan J.; Buffington, Brent B.

2015-01-01

With potential sources of water, energy and other chemicals essential for life, Europa is a top candidate for finding current life in our Solar System outside of Earth. This paper describes the current trajectory design concept for a multiple Europa flyby mission and discusses several trajectory design challenges. The candidate reference trajectory utilizes multiple Europa flybys while around Jupiter to enable near global coverage of Europa while balancing science requirements, radiation dose, propellant usage, and flight time. Trajectory design trades and robustness are also discussed.

Implementation of RF Circuitry for Real-Time Digital Beam-Forming SAR Calibration Schemes

NASA Technical Reports Server (NTRS)

Horst, Stephen J.; Hoffman, James P.; Perkovic-Martin, Dragana; Shaffer, Scott; Thrivikraman, Tushar; Yates, Phil; Veilleux, Louise

2012-01-01

The SweepSAR architecture for space-borne remote sensing applications is an enabling technology for reducing the temporal baseline of repeat-pass interferometers while maintaining near-global coverage. As part of this architecture, real-time digital beam-forming would be performed on the radar return signals across multiple channels. Preserving the accuracy of the combined return data requires real-time calibration of the transmit and receive RF paths on each channel. This paper covers several of the design considerations necessary to produce a practical implementation of this concept.

Reconciling Land-Ocean Moisture Transport Variability in Reanalyses with P-ET in Observationally-Driven Land Surface Models

NASA Technical Reports Server (NTRS)

Robertson, Franklin R.; Bosilovich, Michael G.; Roberts, Jason B.

2016-01-01

Vertically integrated atmospheric moisture transport from ocean to land [vertically integrated atmospheric moisture flux convergence (VMFC)] is a dynamic component of the global climate system but remains problematic in atmospheric reanalyses, with current estimates having significant multidecadal global trends differing even in sign. Continual evolution of the global observing system, particularly stepwise improvements in satellite observations, has introduced discrete changes in the ability of data assimilation to correct systematic model biases, manifesting as nonphysical variability. Land surface models (LSMs) forced with observed precipitation P and near-surface meteorology and radiation provide estimates of evapotranspiration (ET). Since variability of atmospheric moisture storage is small on interannual and longer time scales, VMFC equals P minus ET is a good approximation and LSMs can provide an alternative estimate. However, heterogeneous density of rain gauge coverage, especially the sparse coverage over tropical continents, remains a serious concern. Rotated principal component analysis (RPCA) with prefiltering of VMFC to isolate the artificial variability is used to investigate artifacts in five reanalysis systems. This procedure, although ad hoc, enables useful VMFC corrections over global land. The P minus ET estimates from seven different LSMs are evaluated and subsequently used to confirm the efficacy of the RPCA-based adjustments. Global VMFC trends over the period 1979-2012 ranging from 0.07 to minus 0.03 millimeters per day per decade are reduced by the adjustments to 0.016 millimeters per day per decade, much closer to the LSM P minus ET estimate (0.007 millimeters per day per decade). Neither is significant at the 90 percent level. ENSO (El Nino-Southern Oscillation)-related modulation of VMFC and P minus ET remains the largest global interannual signal, with mean LSM and adjusted reanalysis time series correlating at 0.86.

The global burden of measles in the year 2000--a model that uses country-specific indicators.

PubMed

Stein, Claudia E; Birmingham, Maureen; Kurian, Mary; Duclos, Philippe; Strebel, Peter

2003-05-15

The estimation of the global burden of measles is challenging in the absence of reliable and comparable surveillance systems worldwide. A static model is described that enables estimation of measles morbidity, mortality, and disability for the year 2000 on the basis of country-specific information (i.e., demographic profile, vaccine coverage, and estimates of case-fatality ratios). This approach estimated a global incidence of 39.9 million measles cases, 777,000 deaths, and 28 million disability-adjusted life years. The World Health Organization regions of Africa and Southeast Asia had 70% of incident cases and 84% of measles-related deaths; 11 countries alone (Afghanistan, Burkina Faso, Democratic Republic of the Congo, Ethiopia, India, Indonesia, Niger, Nigeria, Pakistan, Somalia, Uganda) account for 66% of deaths. This approach quantifies the measles burden by considering country-specific indicators, which can be updated, permitting an assessment of country, regional, and global changes in the burden associated with measles infection.

Global Monitoring of Terrestrial Chlorophyll Fluorescence from Moderate-spectral-resolution Near-infrared Satellite Measurements: Methodology, Simulations, and Application to GOME-2

NASA Technical Reports Server (NTRS)

Joiner, J.; Gaunter, L.; Lindstrot, R.; Voigt, M.; Vasilkov, A. P.; Middleton, E. M.; Huemmrich, K. F.; Yoshida, Y.; Frankenberg, C.

2013-01-01

Globally mapped terrestrial chlorophyll fluorescence retrievals are of high interest because they can provide information on the functional status of vegetation including light-use efficiency and global primary productivity that can be used for global carbon cycle modeling and agricultural applications. Previous satellite retrievals of fluorescence have relied solely upon the filling-in of solar Fraunhofer lines that are not significantly affected by atmospheric absorption. Although these measurements provide near-global coverage on a monthly basis, they suffer from relatively low precision and sparse spatial sampling. Here, we describe a new methodology to retrieve global far-red fluorescence information; we use hyperspectral data with a simplified radiative transfer model to disentangle the spectral signatures of three basic components: atmospheric absorption, surface reflectance, and fluorescence radiance. An empirically based principal component analysis approach is employed, primarily using cloudy data over ocean, to model and solve for the atmospheric absorption. Through detailed simulations, we demonstrate the feasibility of the approach and show that moderate-spectral-resolution measurements with a relatively high signal-to-noise ratio can be used to retrieve far-red fluorescence information with good precision and accuracy. The method is then applied to data from the Global Ozone Monitoring Instrument 2 (GOME-2). The GOME-2 fluorescence retrievals display similar spatial structure as compared with those from a simpler technique applied to the Greenhouse gases Observing SATellite (GOSAT). GOME-2 enables global mapping of far-red fluorescence with higher precision over smaller spatial and temporal scales than is possible with GOSAT. Near-global coverage is provided within a few days. We are able to show clearly for the first time physically plausible variations in fluorescence over the course of a single month at a spatial resolution of 0.5 deg × 0.5 deg. We also show some significant differences between fluorescence and coincident normalized difference vegetation indices (NDVI) retrievals.

Global Monitoring of Terrestrial Chlorophyll Fluorescence from Moderate-Spectral-Resolution Near-Infrared Satellite Measurements: Methodology, Simulations, and Application to GOME-2

NASA Technical Reports Server (NTRS)

Joiner, J.; Guanter, L.; Lindstrot, R.; Voigt, M.; Vasilkov, A. P.; Middleton, E. M.; Huemmrich, K. F.; Yoshida, Y.; Frankenberg, C.

2013-01-01

Globally mapped terrestrial chlorophyll fluorescence retrievals are of high interest because they can provide information on the functional status of vegetation including light-use efficiency and global primary productivity that can be used for global carbon cycle modeling and agricultural applications. Previous satellite retrievals of fluorescence have relied solely upon the filling-in of solar Fraunhofer lines that are not significantly affected by atmospheric absorption. Although these measurements provide near-global coverage on a monthly basis, they suffer from relatively low precision and sparse spatial sampling. Here, we describe a new methodology to retrieve global far-red fluorescence information; we use hyperspectral data with a simplified radiative transfer model to disentangle the spectral signatures of three basic components: atmospheric absorption, surface reflectance, and fluorescence radiance. An empirically based principal component analysis approach is employed, primarily using cloudy data over ocean, to model and solve for the atmospheric absorption. Through detailed simulations, we demonstrate the feasibility of the approach and show that moderate-spectral-resolution measurements with a relatively high signal-to-noise ratio can be used to retrieve far-red fluorescence information with good precision and accuracy. The method is then applied to data from the Global Ozone Monitoring Instrument 2 (GOME-2). The GOME-2 fluorescence retrievals display similar spatial structure as compared with those from a simpler technique applied to the Greenhouse gases Observing SATellite (GOSAT). GOME-2 enables global mapping of far-red fluorescence with higher precision over smaller spatial and temporal scales than is possible with GOSAT. Near-global coverage is provided within a few days. We are able to show clearly for the first time physically plausible variations in fluorescence over the course of a single month at a spatial resolution of 0.5 0.5. We also show some significant differences between fluorescence and coincident normalized difference vegetation indices (NDVI) retrievals.

Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae

PubMed Central

Reguly, Teresa; Breitkreutz, Ashton; Boucher, Lorrie; Breitkreutz, Bobby-Joe; Hon, Gary C; Myers, Chad L; Parsons, Ainslie; Friesen, Helena; Oughtred, Rose; Tong, Amy; Stark, Chris; Ho, Yuen; Botstein, David; Andrews, Brenda; Boone, Charles; Troyanskya, Olga G; Ideker, Trey; Dolinski, Kara; Batada, Nizar N; Tyers, Mike

2006-01-01

Background The study of complex biological networks and prediction of gene function has been enabled by high-throughput (HTP) methods for detection of genetic and protein interactions. Sparse coverage in HTP datasets may, however, distort network properties and confound predictions. Although a vast number of well substantiated interactions are recorded in the scientific literature, these data have not yet been distilled into networks that enable system-level inference. Results We describe here a comprehensive database of genetic and protein interactions, and associated experimental evidence, for the budding yeast Saccharomyces cerevisiae, as manually curated from over 31,793 abstracts and online publications. This literature-curated (LC) dataset contains 33,311 interactions, on the order of all extant HTP datasets combined. Surprisingly, HTP protein-interaction datasets currently achieve only around 14% coverage of the interactions in the literature. The LC network nevertheless shares attributes with HTP networks, including scale-free connectivity and correlations between interactions, abundance, localization, and expression. We find that essential genes or proteins are enriched for interactions with other essential genes or proteins, suggesting that the global network may be functionally unified. This interconnectivity is supported by a substantial overlap of protein and genetic interactions in the LC dataset. We show that the LC dataset considerably improves the predictive power of network-analysis approaches. The full LC dataset is available at the BioGRID () and SGD () databases. Conclusion Comprehensive datasets of biological interactions derived from the primary literature provide critical benchmarks for HTP methods, augment functional prediction, and reveal system-level attributes of biological networks. PMID:16762047

Real-Time Monitoring of Vaccination Campaign Performance Using Mobile Phones - Nepal, 2016.

PubMed

Oh, David H; Dabbagh, Alya; Goodson, James L; Strebel, Peter M; Thapa, Sanjita; Giri, Jagat Narain; Shakya, Sagar Ratna; Khanal, Sudhir

2016-10-07

In 2012, the Global Vaccine Action Plan* established a goal to achieve measles and rubella elimination in five of the six World Health Organization (WHO) regions (194 countries) by 2020 (1). Measles elimination strategies aim to achieve ≥95% coverage with 2 routine doses of measles-containing vaccine (2), and implement supplementary immunization activities (SIAs) † in settings where routine coverage is low or where there are subpopulations at high risk. To ensure SIA quality and to achieve ≥95% SIA coverage nationally, rapid convenience monitoring (RCM) is used during or immediately after SIAs (3,4). The objective of RCM is to find unvaccinated children and to identify reasons for nonvaccination in areas with persons at high risk, to enable immediate implementation of corrective actions (e.g., reassigning teams to poorly vaccinated areas, modifying the timing of vaccination, or conducting mop-up vaccination activities). This report describes pilot testing of RCM using mobile phones (RCM-MP) during the second phase of an SIA in Nepal in 2016. Use of RCM-MP resulted in 87% timeliness and 94% completeness of data reporting and found that, although 95% of children were vaccinated, 42% of areas required corrective vaccination activities. RCM-MP challenges included connecting to mobile networks, small phone screen size, and capturing Global Positioning System (GPS) coordinates. Nonetheless, use of RCM-MP led to faster data transmission, analysis, and decision-making and to increased accountability among levels of the health system.

Effect of Investment in Malaria Control on Child Mortality in Sub-Saharan Africa in 2002–2008

PubMed Central

Akachi, Yoko; Atun, Rifat

2011-01-01

Background Around 8.8 million children under-five die each year, mostly due to infectious diseases, including malaria that accounts for 16% of deaths in Africa, but the impact of international financing of malaria control on under-five mortality in sub-Saharan Africa has not been examined. Methods and Findings We combined multiple data sources and used panel data regression analysis to study the relationship among investment, service delivery/intervention coverage, and impact on child health by observing changes in 34 sub-Saharan African countries over 2002–2008. We used Lives Saved Tool to estimate the number of lives saved from coverage increase of insecticide-treated nets (ITNs)/indoor residual spraying (IRS). As an indicator of outcome, we also used under-five mortality rate. Global Fund investments comprised more than 70% of the Official Development Assistance (ODA) for malaria control in 34 countries. Each $1 million ODA for malaria enabled distribution of 50,478 ITNs [95%CI: 37,774–63,182] in the disbursement year. 1,000 additional ITNs distributed saved 0.625 lives [95%CI: 0.369–0.881]. Cumulatively Global Fund investments that increased ITN/IRS coverage in 2002–2008 prevented an estimated 240,000 deaths. Countries with higher malaria burden received less ODA disbursement per person-at-risk compared to lower-burden countries ($3.90 vs. $7.05). Increased ITN/IRS coverage in high-burden countries led to 3,575 lives saved per 1 million children, as compared with 914 lives in lower-burden countries. Impact of ITN/IRS coverage on under-five mortality was significant among major child health interventions such as immunisation showing that 10% increase in households with ITN/IRS would reduce 1.5 [95%CI: 0.3–2.8] child deaths per 1000 live births. Conclusions Along with other key child survival interventions, increased ITNs/IRS coverage has significantly contributed to child mortality reduction since 2002. ITN/IRS scale-up can be more efficiently prioritized to countries where malaria is a major cause of child deaths to save greater number of lives with available resources. PMID:21738633

Near Real-Time Monitoring of Global Evapotranspiration and its Application to Water Resource Management

NASA Astrophysics Data System (ADS)

Halverson, G. H.; Fisher, J.; Jewell, L. A.; Moore, G.; Verma, M.; McDonald, T.; Kim, S.; Muniz, A.

2016-12-01

Water scarcity and its impact on agriculture is a pressing world concern. At the heart of this crisis is the balance of water exchange between the land and the atmosphere. The ability to monitor evapotranspiration provides a solution by enabling sustainable irrigation practices. The Priestley-Taylor Jet Propulsion Laboratory model of evapotranspiration has been implemented to meet this need as a daily MODIS product with 1 to 5 km resolution. An automated data pipeline for this model implementation provides daily data with global coverage and near real-time latency using the Geospatial Data Abstraction Library. An interactive map providing on-demand statistical analysis enables water resource managers to monitor rates of water loss. To demonstrate the application of remotely-sensed evapotranspiration to water resource management, a partnership has been arranged with the New Mexico Office of the State Engineer (NMOSE). The online water research management tool was developed to meet the specifications of NMOSE using the Leaflet, GeoServer, and Django frameworks. NMOSE will utilize this tool to monitor drought and fire risk and manage irrigation. Through this test-case, it is hoped that real-time, user-friendly remote sensing tools will be adopted globally to make resource management decisions informed by the NASA Earth Observation System.

The 'Book of Life' in the press: comparing German and Irish media discourse on human genome research.

PubMed

O'Mahony, Patrick; Schäfer, Mike Steffen

2005-02-01

The essay compares German and Irish media coverage of human genome research in the year 2000, using qualitative and quantitative frame analysis of a print media corpus. Drawing from a media-theoretical account of science communication, the study examines four analytic dimensions: (1) the influence of global and national sources of discourse; (2) the nature of elaboration on important themes; (3) the extent of societal participation in discourse production; (4) the cultural conditions in which the discourse resonates. The analysis shows that a global discursive package, emphasizing claims of scientific achievement and medical progress, dominates media coverage in both countries. However, German coverage is more extensive and elaborate, and includes a wider range of participants. Irish coverage more often incorporates the global package without further elaboration. These finding indicate that the global package is 'localized' differently due to national patterns of interests, German participation in human genome research, traditions of media coverage, and the domestic resonance of the issue.

Human resources for health and universal health coverage: fostering equity and effective coverage.

PubMed

Campbell, James; Buchan, James; Cometto, Giorgio; David, Benedict; Dussault, Gilles; Fogstad, Helga; Fronteira, Inês; Lozano, Rafael; Nyonator, Frank; Pablos-Méndez, Ariel; Quain, Estelle E; Starrs, Ann; Tangcharoensathien, Viroj

2013-11-01

Achieving universal health coverage (UHC) involves distributing resources, especially human resources for health (HRH), to match population needs. This paper explores the policy lessons on HRH from four countries that have achieved sustained improvements in UHC: Brazil, Ghana, Mexico and Thailand. Its purpose is to inform global policy and financial commitments on HRH in support of UHC. The paper reports on country experiences using an analytical framework that examines effective coverage in relation to the availability, accessibility, acceptability and quality (AAAQ) of HRH. The AAAQ dimensions make it possible to perform tracing analysis on HRH policy actions since 1990 in the four countries of interest in relation to national trends in workforce numbers and population mortality rates. The findings inform key principles for evidence-based decision-making on HRH in support of UHC. First, HRH are critical to the expansion of health service coverage and the package of benefits; second, HRH strategies in each of the AAAQ dimensions collectively support achievements in effective coverage; and third, success is achieved through partnerships involving health and non-health actors. Facing the unprecedented health and development challenges that affect all countries and transforming HRH evidence into policy and practice must be at the heart of UHC and the post-2015 development agenda. It is a political imperative requiring national commitment and leadership to maximize the impact of available financial and human resources, and improve healthy life expectancy, with the recognition that improvements in health care are enabled by a health workforce that is fit for purpose.

Human resources for health and universal health coverage: fostering equity and effective coverage

PubMed Central

Buchan, James; Cometto, Giorgio; David, Benedict; Dussault, Gilles; Fogstad, Helga; Fronteira, Inês; Lozano, Rafael; Nyonator, Frank; Pablos-Méndez, Ariel; Quain, Estelle E; Starrs, Ann; Tangcharoensathien, Viroj

2013-01-01

Abstract Achieving universal health coverage (UHC) involves distributing resources, especially human resources for health (HRH), to match population needs. This paper explores the policy lessons on HRH from four countries that have achieved sustained improvements in UHC: Brazil, Ghana, Mexico and Thailand. Its purpose is to inform global policy and financial commitments on HRH in support of UHC. The paper reports on country experiences using an analytical framework that examines effective coverage in relation to the availability, accessibility, acceptability and quality (AAAQ) of HRH. The AAAQ dimensions make it possible to perform tracing analysis on HRH policy actions since 1990 in the four countries of interest in relation to national trends in workforce numbers and population mortality rates. The findings inform key principles for evidence-based decision-making on HRH in support of UHC. First, HRH are critical to the expansion of health service coverage and the package of benefits; second, HRH strategies in each of the AAAQ dimensions collectively support achievements in effective coverage; and third, success is achieved through partnerships involving health and non-health actors. Facing the unprecedented health and development challenges that affect all countries and transforming HRH evidence into policy and practice must be at the heart of UHC and the post-2015 development agenda. It is a political imperative requiring national commitment and leadership to maximize the impact of available financial and human resources, and improve healthy life expectancy, with the recognition that improvements in health care are enabled by a health workforce that is fit for purpose. PMID:24347710

A Nested Phosphorus and Proton Coil Array for Brain Magnetic Resonance Imaging and Spectroscopy

PubMed Central

Brown, Ryan; Lakshmanan, Karthik; Madelin, Guillaume; Parasoglou, Prodromos

2015-01-01

A dual-nuclei radiofrequency coil array was constructed for phosphorus and proton magnetic resonance imaging and spectroscopy of the human brain at 7 Tesla. An eight-channel transceive degenerate birdcage phosphorus module was implemented to provide whole-brain coverage and significant sensitivity improvement over a standard dual-tuned loop coil. A nested eight-channel proton module provided adequate sensitivity for anatomical localization without substantially sacrificing performance on the phosphorus module. The developed array enabled phosphorus spectroscopy, a saturation transfer technique to calculate the global creatine kinase forward reaction rate, and single-metabolite whole-brain imaging with 1.4 cm nominal isotropic resolution in 15 min (2.3 cm actual resolution), while additionally enabling 1 mm isotropic proton imaging. This study demonstrates that a multi-channel array can be utilized for phosphorus and proton applications with improved coverage and/or sensitivity over traditional single-channel coils. The efficient multi-channel coil array, time-efficient pulse sequences, and the enhanced signal strength available at ultra-high fields can be combined to allow volumetric assessment of the brain and could provide new insights into the underlying energy metabolism impairment in several neurodegenerative conditions, such as Alzheimer’s and Parkinson’s diseases, as well as mental disorders such as schizophrenia. PMID:26375209

A nested phosphorus and proton coil array for brain magnetic resonance imaging and spectroscopy.

PubMed

Brown, Ryan; Lakshmanan, Karthik; Madelin, Guillaume; Parasoglou, Prodromos

2016-01-01

A dual-nuclei radiofrequency coil array was constructed for phosphorus and proton magnetic resonance imaging and spectroscopy of the human brain at 7T. An eight-channel transceive degenerate birdcage phosphorus module was implemented to provide whole-brain coverage and significant sensitivity improvement over a standard dual-tuned loop coil. A nested eight-channel proton module provided adequate sensitivity for anatomical localization without substantially sacrificing performance on the phosphorus module. The developed array enabled phosphorus spectroscopy, a saturation transfer technique to calculate the global creatine kinase forward reaction rate, and single-metabolite whole-brain imaging with 1.4cm nominal isotropic resolution in 15min (2.3cm actual resolution), while additionally enabling 1mm isotropic proton imaging. This study demonstrates that a multi-channel array can be utilized for phosphorus and proton applications with improved coverage and/or sensitivity over traditional single-channel coils. The efficient multi-channel coil array, time-efficient pulse sequences, and the enhanced signal strength available at ultra-high fields can be combined to allow volumetric assessment of the brain and could provide new insights into the underlying energy metabolism impairment in several neurodegenerative conditions, such as Alzheimer's and Parkinson's diseases, as well as mental disorders such as schizophrenia. Copyright © 2015 Elsevier Inc. All rights reserved.

NASA Tools for Climate Impacts on Water Resources

NASA Technical Reports Server (NTRS)

Toll, David; Doorn, Brad

2010-01-01

Climate and environmental change are expected to fundamentally alter the nation's hydrological cycle and water availability. Satellites provide global or near-global coverage using instruments, allowing for consistent, well-calibrated, and equivalent-quality data of the Earth system. A major goal for NASA climate and environmental change research is to create multi-instrument data sets to span the multi-decadal time scales of climate change and to combine these data with those from modeling and surface-based observing systems to improve process understanding and predictions. NASA and Earth science data and analyses will ultimately enable more accurate climate prediction, and characterization of uncertainties. NASA's Applied Sciences Program works with other groups, including other federal agencies, to transition demonstrated observational capabilities to operational capabilities. A summary of some of NASA tools for improved water resources management will be presented.

The Soil Moisture Active and Passive Mission (SMAP): Science and Applications

NASA Technical Reports Server (NTRS)

Entekhabi, Dara; O'Neill, Peggy; Njoku, Eni

2009-01-01

The Soil Moisture Active and Passive mission (SMAP) will provide global maps of soil moisture content and surface freeze/thaw state. Global measurements of these variables are critical for terrestrial water and carbon cycle applications. The SMAP observatory consists of two multipolarization L-band sensors, a radar and radiometer, that share a deployable-mesh reflector antenna. The combined observations from the two sensors will allow accurate estimation of soil moisture at hydrometeorological (10 km) and hydroclimatological (40 km) spatial scales. The rotating antenna configuration provides conical scans of the Earth surface at a constant look angle. The wide-swath (1000 km) measurements will allow global mapping of soil moisture and its freeze/thaw state with 2-3 days revisit. Freeze/thaw in boreal latitudes will be mapped using the radar at 3 km resolution with 1-2 days revisit. The synergy of active and passive observations enables measurements of soil moisture and freeze/thaw state with unprecedented resolution, sensitivity, area coverage and revisit.

Global Coverage from Ad-Hoc Constellations in Rideshare Orbits

NASA Technical Reports Server (NTRS)

Ellis, Armin; Mercury, Michael; Brown, Shannon

2012-01-01

A promising area of small satellite development is in providing higher temporal resolution than larger satellites. Traditional constellations have required specific orbits and dedicated launch vehicles. In this paper we discuss an alternative architecture in which the individual elements of the constellation are launched as rideshare opportunities. We compare the coverage of such an ad-hoc constellation with more traditional constellations. Coverage analysis is based on actual historical data from rideshare opportunities. Our analysis includes ground coverage and temporal revisits for Polar, Tropics, Temperate, and Global regions, comparing ad-hoc and Walker constellation.

Transforming Global Health by Improving the Science of Scale-Up

PubMed Central

Kruk, Margaret E.; Yamey, Gavin; Angell, Sonia Y.; Beith, Alix; Cotlear, Daniel; Guanais, Frederico; Jacobs, Lisa; Saxenian, Helen; Victora, Cesar; Goosby, Eric

2016-01-01

In its report Global Health 2035, the Commission on Investing in Health proposed that health investments can reduce mortality in nearly all low- and middle-income countries to very low levels, thereby averting 10 million deaths per year from 2035 onward. Many of these gains could be achieved through scale-up of existing technologies and health services. A key instrument to close this gap is policy and implementation research (PIR) that aims to produce generalizable evidence on what works to implement successful interventions at scale. Rigorously designed PIR promotes global learning and local accountability. Much greater national and global investments in PIR capacity will be required to enable the scaling of effective approaches and to prevent the recycling of failed ideas. Sample questions for the PIR research agenda include how to close the gap in the delivery of essential services to the poor, which population interventions for non-communicable diseases are most applicable in different contexts, and how to engage non-state actors in equitable provision of health services in the context of universal health coverage. PMID:26934704

Partisan differences in the relationship between newspaper coverage and concern over global warming.

PubMed

Zhao, Xiaoquan; Rolfe-Redding, Justin; Kotcher, John E

2016-07-01

The effects of news media on public opinion about global warming have been a topic of much interest in both academic and popular discourse. Empirical evidence in this regard, however, is still limited and somewhat mixed. This study used data from the 2006 General Social Survey in combination with a content analysis of newspaper coverage of the same time period to examine the relationship between general news climate and public concern about global warming. Results showed a pattern of political polarization, with increased coverage associated with growing divergence between Democrats and Republicans. Further analysis also showed evidence of reactivity in partisan response to coverage from different news outlets. These findings point to a particular form of politically motivated, biased processing of news information. © The Author(s) 2014.

Hydrologic Conditions Viewed by the Nimbus Meteorological Satellites

NASA Technical Reports Server (NTRS)

Rabchevsky, G. A.

1971-01-01

The unexploited value of the Nimbus meteorological sensor data relates to the satellites' ability for global, temporal, repetitive and uniform tonal and spatial coverage of the earth's surface. Examples are presented illustrating how synoptic views of large areas increase interpretive capability and enable focusing on large targets of interest. The effect of resolution of the Nimbus imaging systems on these observations is discussed, together with the assessment of the areal and temporal magnitude of changes observed by these systems. Two case studies are presented exemplifying the satellites' ability for repetitive observations enabling phenomena to be monitored under special conditions. One study deals with changes observed in the Antarctic ice conditions utilizing the Nimbus 2 and 3 television picture data. The other study deals with terrestrial changes in the Mississippi River Valley and the Niger River Valley (Africa), observed primarily in the 0.7 to 1.3 micron spectral band.

Realizing Universal Health Coverage in East Africa: the relevance of human rights.

PubMed

Yamin, Alicia Ely; Maleche, Allan

2017-08-03

Applying a robust human rights framework would change thinking and decision-making in efforts to achieve Universal Health Coverage (UHC), and advance efforts to promote women's, children's, and adolescents' health in East Africa, which is a priority under the Sustainable Development Agenda. Nevertheless, there is a gap between global rhetoric of human rights and ongoing health reform efforts. This debate article seeks to fill part of that gap by setting out principles of human rights-based approaches (HRBAs), and then applying those principles to questions that countries undertaking efforts toward UHC and promoting women's, children's and adolescents' health, will need to face, focusing in particular on ensuring enabling legal and policy frameworks, establishing fair financing; priority-setting processes, and meaningful oversight and accountability mechanisms. In a region where democratic institutions are notoriously weak, we argue that the explicit application of a meaningful human rights framework could enhance equity, participation and accountability, and in turn the democratic legitimacy of health reform initiatives being undertaken in the region.

Navigation of autonomous vehicles for oil spill cleaning in dynamic and uncertain environments

NASA Astrophysics Data System (ADS)

Jin, Xin; Ray, Asok

2014-04-01

In the context of oil spill cleaning by autonomous vehicles in dynamic and uncertain environments, this paper presents a multi-resolution algorithm that seamlessly integrates the concepts of local navigation and global navigation based on the sensory information; the objective here is to enable adaptive decision making and online replanning of vehicle paths. The proposed algorithm provides a complete coverage of the search area for clean-up of the oil spills and does not suffer from the problem of having local minima, which is commonly encountered in potential-field-based methods. The efficacy of the algorithm is tested on a high-fidelity player/stage simulator for oil spill cleaning in a harbour, where the underlying oil weathering process is modelled as 2D random-walk particle tracking. A preliminary version of this paper was presented by X. Jin and A. Ray as 'Coverage Control of Autonomous Vehicles for Oil Spill Cleaning in Dynamic and Uncertain Environments', Proceedings of the American Control Conference, Washington, DC, June 2013, pp. 2600-2605.

Evolution of Satellite Imagers and Sounders for Low Earth Orbit and Technology Directions at NASA

NASA Technical Reports Server (NTRS)

Pagano, Thomas S.; McClain, Charles R.

2010-01-01

Imagers and Sounders for Low Earth Orbit (LEO) provide fundamental global daily observations of the Earth System for scientists, researchers, and operational weather agencies. The imager provides the nominal 1-2 km spatial resolution images with global coverage in multiple spectral bands for a wide range of uses including ocean color, vegetation indices, aerosol, snow and cloud properties, and sea surface temperature. The sounder provides vertical profiles of atmospheric temperature, water vapor cloud properties, and trace gases including ozone, carbon monoxide, methane and carbon dioxide. Performance capabilities of these systems has evolved with the optical and sensing technologies of the decade. Individual detectors were incorporated on some of the first imagers and sounders that evolved to linear array technology in the '80's. Signal-to-noise constraints limited these systems to either broad spectral resolution as in the case of the imager, or low spatial resolution as in the case of the sounder. Today's area 2-dimensional large format array technology enables high spatial and high spectral resolution to be incorporated into a single instrument. This places new constraints on the design of these systems and enables new capabilities for scientists to examine the complex processes governing the Earth System.

Cultured Construction: Global Evidence of the Impact of National Values on Piped-to-Premises Water Infrastructure Development.

PubMed

Kaminsky, Jessica A

2016-07-19

In 2016, the global community undertook the Sustainable Development Goals. One of these goals seeks to achieve universal and equitable access to safe and affordable drinking water for all people by the year 2030. In support of this undertaking, this paper seeks to discover the cultural work done by piped water infrastructure across 33 nations with developed and developing economies that have experienced change in the percentage of population served by piped-to-premises water infrastructure at the national level of analysis. To do so, I regressed the 1990-2012 change in piped-to-premises water infrastructure coverage against Hofstede's cultural dimensions, controlling for per capita GDP, the 1990 baseline level of coverage, percent urban population, overall 1990-2012 change in improved sanitation (all technologies), and per capita freshwater resources. Separate analyses were carried out for the urban, rural, and aggregate national contexts. Hofstede's dimensions provide a measure of cross-cultural difference; high or low scores are not in any way intended to represent better or worse but rather serve as a quantitative way to compare aggregate preferences for ways of being and doing. High scores in the cultural dimensions of Power Distance, Individualism-Collectivism, and Uncertainty Avoidance explain increased access to piped-to-premises water infrastructure in the rural context. Higher Power Distance and Uncertainty Avoidance scores are also statistically significant for increased coverage in the urban and national aggregate contexts. These results indicate that, as presently conceived, piped-to-premises water infrastructure fits best with spatial contexts that prefer hierarchy and centralized control. Furthermore, water infrastructure is understood to reduce uncertainty regarding the provision of individually valued benefits. The results of this analysis identify global trends that enable engineers and policy makers to design and manage more culturally appropriate and socially sustainable water infrastructure by better fitting technologies to user preferences.

Effects of finite coverage on global polarization observables in heavy ion collisions

NASA Astrophysics Data System (ADS)

Lan, Shaowei; Lin, Zi-Wei; Shi, Shusu; Sun, Xu

2018-05-01

In non-central relativistic heavy ion collisions, the created matter possesses a large initial orbital angular momentum. Particles produced in the collisions could be polarized globally in the direction of the orbital angular momentum due to spin-orbit coupling. Recently, the STAR experiment has presented polarization signals for Λ hyperons and possible spin alignment signals for ϕ mesons. Here we discuss the effects of finite coverage on these observables. The results from a multi-phase transport and a toy model both indicate that a pseudorapidity coverage narrower than | η | < ∼ 1 will generate a larger value for the extracted ϕ-meson ρ00 parameter; thus a finite coverage can lead to an artificial deviation of ρ00 from 1/3. We also show that a finite η and pT coverage affect the extracted pH parameter for Λ hyperons when the real pH value is non-zero. Therefore proper corrections are necessary to reliably quantify the global polarization with experimental observables.

Two years of LCOGT operations: the challenges of a global observatory

NASA Astrophysics Data System (ADS)

Volgenau, Nikolaus; Boroson, Todd

2016-07-01

With 18 telescopes distributed over 6 sites, and more telescopes being added in 2016, Las Cumbres Observatory Global Telescope Network is a unique resource for timedomain astronomy. The Network's continuous coverage of the night sky, and the optimization of the observing schedule over all sites simultaneously, have enabled LCOGTusers to produce significant science results. However, practical challenges to maximizing the Network's science output remain. The Network began providing observations for members of its Science Collaboration and other partners in May 2014. In the two years since then, LCOGT has made a number of improvements to increase the Network's science yield. We also now have two years' experience monitoring observatory performance; effective monitoring of an observatory that spans the globe is a complex enterprise. Here, we describe some of LCOGT's efforts to monitor the Network, assess the quality of science data, and improve communication with our users.

Global, quantitative and dynamic mapping of protein subcellular localization.

PubMed

Itzhak, Daniel N; Tyanova, Stefka; Cox, Jürgen; Borner, Georg Hh

2016-06-09

Subcellular localization critically influences protein function, and cells control protein localization to regulate biological processes. We have developed and applied Dynamic Organellar Maps, a proteomic method that allows global mapping of protein translocation events. We initially used maps statically to generate a database with localization and absolute copy number information for over 8700 proteins from HeLa cells, approaching comprehensive coverage. All major organelles were resolved, with exceptional prediction accuracy (estimated at >92%). Combining spatial and abundance information yielded an unprecedented quantitative view of HeLa cell anatomy and organellar composition, at the protein level. We subsequently demonstrated the dynamic capabilities of the approach by capturing translocation events following EGF stimulation, which we integrated into a quantitative model. Dynamic Organellar Maps enable the proteome-wide analysis of physiological protein movements, without requiring any reagents specific to the investigated process, and will thus be widely applicable in cell biology.

Overview of Global, Regional, and National Routine Vaccination Coverage Trends and Growth Patterns From 1980 to 2009: Implications for Vaccine-Preventable Disease Eradication and Elimination Initiatives

PubMed Central

Wallace, Aaron S.; Ryman, Tove K.; Dietz, Vance

2015-01-01

Background Review of the historical growth in annual vaccination coverage across countries and regions can better inform decision makers’ development of future goals and strategies to improve routine vaccination services. Methods Using the World Health Organization (WHO) and the United Nations Children's Fund estimates of annual national third dose of diphtheria-tetanus-pertussis–containing vaccine (DTP3) and third dose of polio vaccine (POL3) coverage for 1980–2009, we calculated the mean absolute annual rate of change in national DTP3 coverage among all countries (globally) and among countries within each WHO region, as well as the number of years taken by each region to reach specific regional coverage levels. Last, we assessed differences in mean absolute annual rate of change in DTP3 coverage, stratified by baseline level of DTP3 coverage. Results During the 1980s, global DTP3 coverage increased a mean of 5.3 percentage points/year. Annual rate of change decreased to 0.5 percentage points/year in the 1990s and then increased to 0.9 percentage points/year during the 2000s. Mean annual rate of change in coverage across all countries was highest (9.2 percentage points) when national coverage levels were 26%–30% and lowest (−0.9 percentage points) when national coverage levels were 96%–100%. Regional differences existed as both WHO South-East Asia Region and WHO African Region countries experienced mean negative DTP3 coverage growth at lower coverage levels (81%–85%) than other regions. The regions that have achieved 95% DTP3 coverage (Americas, Western Pacific, and European) took 25–29 years to reach that level from a level of 50% DTP3 coverage. POL3 coverage change trends were similar to described DTP3 coverage change trends. Conclusions Mean national coverage growth patterns across all regions are nonlinear as coverage levels increase. Saturation points of mean 0 percentage-point growth in annual coverage varies by region and require further investigation. The achievement of >90% routine coverage is observed to take decades, which has implications for disease eradication and elimination initiatives. PMID:25316875

Equity-Oriented Monitoring in the Context of Universal Health Coverage

PubMed Central

Hosseinpoor, Ahmad Reza; Bergen, Nicole; Koller, Theadora; Prasad, Amit; Schlotheuber, Anne; Valentine, Nicole; Lynch, John; Vega, Jeanette

2014-01-01

Monitoring inequalities in health is fundamental to the equitable and progressive realization of universal health coverage (UHC). A successful approach to global inequality monitoring must be intuitive enough for widespread adoption, yet maintain technical credibility. This article discusses methodological considerations for equity-oriented monitoring of UHC, and proposes recommendations for monitoring and target setting. Inequality is multidimensional, such that the extent of inequality may vary considerably across different dimensions such as economic status, education, sex, and urban/rural residence. Hence, global monitoring should include complementary dimensions of inequality (such as economic status and urban/rural residence) as well as sex. For a given dimension of inequality, subgroups for monitoring must be formulated taking into consideration applicability of the criteria across countries and subgroup heterogeneity. For economic-related inequality, we recommend forming subgroups as quintiles, and for urban/rural inequality we recommend a binary categorization. Inequality spans populations, thus appropriate approaches to monitoring should be based on comparisons between two subgroups (gap approach) or across multiple subgroups (whole spectrum approach). When measuring inequality absolute and relative measures should be reported together, along with disaggregated data; inequality should be reported alongside the national average. We recommend targets based on proportional reductions in absolute inequality across populations. Building capacity for health inequality monitoring is timely, relevant, and important. The development of high-quality health information systems, including data collection, analysis, interpretation, and reporting practices that are linked to review and evaluation cycles across health systems, will enable effective global and national health inequality monitoring. These actions will support equity-oriented progressive realization of UHC. PMID:25243463

[Equity-oriented monitoring in the context of universal health coverage].

PubMed

Hosseinpoor, Ahmad Reza; Bergen, Nicole; Koller, Theadora; Prasad, Amit; Schlotheuber, Anne; Valentine, Nicole; Lynch, John; Vega, Jeanette

2015-07-01

Monitoring inequalities in health is fundamental to the equitable and progressive realization of universal health coverage (UHC). A successful approach to global inequality monitoring must be intuitive enough for widespread adoption, yet maintain technical credibility. This article discusses methodological considerations for equity-oriented monitoring of UHC, and proposes recommendations for monitoring and target setting. Inequality is multidimensional, such that the extent of inequality may vary considerably across different dimensions such as economic status, education, sex, and urban/rural residence. Hence, global monitoring should include complementary dimensions of inequality (such as economic status and urban/rural residence) as well as sex. For a given dimension of inequality, subgroups for monitoring must be formulated taking into consideration applicability of the criteria across countries and subgroup heterogeneity. For economic-related inequality, we recommend forming subgroups as quintiles, and for urban/rural inequality we recommend a binary categorization. Inequality spans populations, thus appropriate approaches to monitoring should be based on comparisons between two subgroups (gap approach) or across multiple subgroups (whole spectrum approach). When measuring inequality absolute and relative measures should be reported together, along with disaggregated data; inequality should be reported alongside the national average. We recommend targets based on proportional reductions in absolute inequality across populations. Building capacity for health inequality monitoring is timely, relevant, and important. The development of high-quality health information systems, including data collection, analysis, interpretation, and reporting practices that are linked to review and evaluation cycles across health systems, will enable effective global and national health inequality monitoring. These actions will support equity-oriented progressive realization of UHC.

The affordability for patients of a new universal MDR-TB coverage model in China.

PubMed

Ruan, Y-Z; Li, R-Z; Wang, X-X; Wang, L-X; Sun, Q; Chen, C; Xu, C-H; Su, W; Zhao, J; Pang, Y; Cheng, J; Wang, Q; Fu, Y-T; Huan, S-T; Chen, M-T; Scano, F; Floyd, K; Chin, D P; Fitzpatrick, C

2016-05-01

China has piloted a new model of universal coverage for multidrug-resistant tuberculosis (MDR-TB), designed to rationalize hospital use of drugs and tests and move away from fee-for-service payment towards a standard package with financial protection against catastrophic health costs. To evaluate the affordability to patients of this new model. This was an observational study of 243 MDR-TB cases eligible for enrolment on treatment under the project. We assessed the affordability of the project from the perspective of households, with a focus on catastrophic costs. Of the 243 eligible cases, 172 (71%) were enrolled on treatment; of the 71 cases not enrolled, 26 (37%) cited economic reasons. The 73 surveyed cases paid an average of RMB 5977 (US$920) out-of-pocket in search costs incurred outside the pilot model. Within the pilot, they paid another RMB 2094 (US$322) in medical fees and RMB 5230 (US$805) in direct non-medical costs. Despite 90% reimbursement of medical fees, 78% of households experienced catastrophic costs, including indirect costs. The objectives of the pilot model are aligned with health reform in China and universal health coverage globally. Enrollment would almost certainly be higher with 100% reimbursement of medical fees, but patient enablers will be required to truly eliminate catastrophic costs.

Stable Satellite Orbits for Global Coverage of the Moon

NASA Technical Reports Server (NTRS)

Ely, Todd; Lieb, Erica

2006-01-01

A document proposes a constellation of spacecraft to be placed in orbit around the Moon to provide navigation and communication services with global coverage required for exploration of the Moon. There would be six spacecraft in inclined elliptical orbits: three in each of two orthogonal orbital planes, suggestive of a linked-chain configuration. The orbits have been chosen to (1) provide 99.999-percent global coverage for ten years and (2) to be stable under perturbation by Earth gravitation and solar-radiation pressure, so that no deterministic firing of thrusters would be needed to maintain the orbits. However, a minor amount of orbit control might be needed to correct for such unmodeled effects as outgassing of the spacecraft.

Datacube Interoperability, Encoding Independence, and Analytics

NASA Astrophysics Data System (ADS)

Baumann, Peter; Hirschorn, Eric; Maso, Joan

2017-04-01

Datacubes are commonly accepted as an enabling paradigm which provides a handy abstraction for accessing and analyzing the zillions of image files delivered by the manifold satellite instruments and climate simulations, among others. Additionally, datacubes are the classic model for statistical and OLAP datacubes, so a further information category can be integrated. From a standards perspective, spatio-temporal datacubes naturally are included in the concept of coverages which encompass regular and irregular grids, point clouds, and general meshes - or, more abstractly, digital representations of spatio-temporally varying phenomena. ISO 19123, which is identical to OGC Abstract Topic 6, gives a high-level abstract definition which is complemented by the OGC Coverage Implementation Schema (CIS) which is an interoperable, yet format independent concretization of the abstract model. Currently, ISO is working on adopting OGC CIS as ISO 19123-2; the existing ISO 19123 standard is under revision by one of the abstract authors and will become ISO 19123-1. The roadmap agreed by ISO further foresees adoption of the OGC Web Coverage Service (WCS) as an ISO standard so that a complete data and service model will exist. In 2016, INSPIRE has adopted WCS as Coverage Download Service, including the datacube analytics language Web Coverage Processing Service (WCPS). The rasdaman technology (www.rasdaman.org) is both OGC and INSPIRE Reference Implementation. In the global EarthServer initiative rasdaman database sizes are exceeding 250 TB today, heading for the Petabyte frontier well in 2017. Technically, CIS defines a compact, efficient model for representing multi-dimensional datacubes in several ways. The classical coverage cube defines a domain set (where are values?), a range set (what are these values?), and range type (what do the values mean?), as well as a "bag" for arbitrary metadata. With CIS 1.1, coordinate/value pair sequences have been added, as well as tiled representations. Further, CIS 1.1 offers a unified model for any kind of regular and irregular grids, also allowing sensor models as per SensorML. Encodings include ASCII formats like GML, JSON, RDF as well as binary formats like GeoTIFF, NetCDF, JPEG2000, and GRIB2; further, a container concept allows mixed representations within one coverage file utilizing zip or other convenient package formats. Through the tight integration with the Sensor Web Enablement (SWE), a lossless "transport" from sensor into coverage world is ensured. The corresponding service model of WCS supports datacube operations ranging from simple data extraction to complex ad-hoc analytics with WPCS. Notably, W3C is working has set out on a coverage model as well; it has been designed relatively independently from the abovementioned standards, but there is informal agreement to link it into the CIS universe (which allows for different, yet interchangeable representations). Particularly interesting in the W3C proposal is the detailed semantic modeling of metadata; as CIS 1.1 supports RDF, a tight coupling seems feasible.

Sentinel-3 coverage-driven mission design: Coupling of orbit selection and instrument design

NASA Astrophysics Data System (ADS)

Cornara, S.; Pirondini, F.; Palmade, J. L.

2017-11-01

The first satellite of the Sentinel-3 series was launched in February 2016. Sentinel-3 payload suite encompasses the Ocean and Land Colour Instrument (OLCI) with a swath of 1270 km, the Sea and Land Surface Temperature Radiometer (SLSTR) yielding a dual-view scan with swaths of 1420 km (nadir) and 750 km (oblique view), the Synthetic Aperture Radar Altimeter (SRAL) working in Ku-band and C-band, and the dual-frequency Microwave Radiometer (MWR). In the early stages of mission and system design, the main driver for the Sentinel-3 reference orbit selection was the requirement to achieve a revisit time of two days or less globally over ocean areas with two satellites (i.e. 4-day global coverage with one satellite). The orbit selection was seamlessly coupled with the OLCI instrument design in terms of field of view (FoV) definition driven by the observation zenith angle (OZA) and sunglint constraints applied to ocean observations. The criticality of the global coverage requirement for ocean monitoring derives from the sunglint phenomenon, i.e. the impact on visible channels of the solar ray reflection on the water surface. This constraint was finally overcome thanks to the concurrent optimisation of the orbit parameters, notably the Local Time at Descending Node (LTDN), and the OLCI instrument FoV definition. The orbit selection process started with the identification of orbits with short repeat cycle (2-4 days), firstly to minimise the time required to achieve global coverage with existing constraints, and then to minimise the swath required to obtain global coverage and the maximum required OZA. This step yielded the selection of a 4-day repeat cycle orbit, thus allowing 2-day coverage with two adequately spaced satellites. Then suitable candidate orbits with higher repeat cycles were identified in the proximity of the selected altitudes and the reference orbit was ultimately chosen. Rationale was to keep the swath for global coverage as close as possible to the previous optimum value, but to tailor the repeat cycle length (i.e. the ground-track grid) to optimise the topography mission performances. The final choice converged on the sun-synchronous orbit 14 + 7/27, reference altitude ∼800 km, LTDN = 10h00. Extensive coverage analyses were carried out to characterise the mission performance and the fulfilment of the requirements, encompassing revisit time, number of acquisitions, observation viewing geometry and swath properties. This paper presents a comprehensive overview of the Sentinel-3 orbit selection, starting from coverage requirements and highlighting the close interaction with the instrument design activity.

Phylogenetic classification of the world's tropical forests.

PubMed

Slik, J W Ferry; Franklin, Janet; Arroyo-Rodríguez, Víctor; Field, Richard; Aguilar, Salomon; Aguirre, Nikolay; Ahumada, Jorge; Aiba, Shin-Ichiro; Alves, Luciana F; K, Anitha; Avella, Andres; Mora, Francisco; Aymard C, Gerardo A; Báez, Selene; Balvanera, Patricia; Bastian, Meredith L; Bastin, Jean-François; Bellingham, Peter J; van den Berg, Eduardo; da Conceição Bispo, Polyanna; Boeckx, Pascal; Boehning-Gaese, Katrin; Bongers, Frans; Boyle, Brad; Brambach, Fabian; Brearley, Francis Q; Brown, Sandra; Chai, Shauna-Lee; Chazdon, Robin L; Chen, Shengbin; Chhang, Phourin; Chuyong, George; Ewango, Corneille; Coronado, Indiana M; Cristóbal-Azkarate, Jurgi; Culmsee, Heike; Damas, Kipiro; Dattaraja, H S; Davidar, Priya; DeWalt, Saara J; Din, Hazimah; Drake, Donald R; Duque, Alvaro; Durigan, Giselda; Eichhorn, Karl; Eler, Eduardo Schmidt; Enoki, Tsutomu; Ensslin, Andreas; Fandohan, Adandé Belarmain; Farwig, Nina; Feeley, Kenneth J; Fischer, Markus; Forshed, Olle; Garcia, Queila Souza; Garkoti, Satish Chandra; Gillespie, Thomas W; Gillet, Jean-Francois; Gonmadje, Christelle; Granzow-de la Cerda, Iñigo; Griffith, Daniel M; Grogan, James; Hakeem, Khalid Rehman; Harris, David J; Harrison, Rhett D; Hector, Andy; Hemp, Andreas; Homeier, Jürgen; Hussain, M Shah; Ibarra-Manríquez, Guillermo; Hanum, I Faridah; Imai, Nobuo; Jansen, Patrick A; Joly, Carlos Alfredo; Joseph, Shijo; Kartawinata, Kuswata; Kearsley, Elizabeth; Kelly, Daniel L; Kessler, Michael; Killeen, Timothy J; Kooyman, Robert M; Laumonier, Yves; Laurance, Susan G; Laurance, William F; Lawes, Michael J; Letcher, Susan G; Lindsell, Jeremy; Lovett, Jon; Lozada, Jose; Lu, Xinghui; Lykke, Anne Mette; Mahmud, Khairil Bin; Mahayani, Ni Putu Diana; Mansor, Asyraf; Marshall, Andrew R; Martin, Emanuel H; Calderado Leal Matos, Darley; Meave, Jorge A; Melo, Felipe P L; Mendoza, Zhofre Huberto Aguirre; Metali, Faizah; Medjibe, Vincent P; Metzger, Jean Paul; Metzker, Thiago; Mohandass, D; Munguía-Rosas, Miguel A; Muñoz, Rodrigo; Nurtjahy, Eddy; de Oliveira, Eddie Lenza; Onrizal; Parolin, Pia; Parren, Marc; Parthasarathy, N; Paudel, Ekananda; Perez, Rolando; Pérez-García, Eduardo A; Pommer, Ulf; Poorter, Lourens; Qie, Lan; Piedade, Maria Teresa F; Pinto, José Roberto Rodrigues; Poulsen, Axel Dalberg; Poulsen, John R; Powers, Jennifer S; Prasad, Rama Chandra; Puyravaud, Jean-Philippe; Rangel, Orlando; Reitsma, Jan; Rocha, Diogo S B; Rolim, Samir; Rovero, Francesco; Rozak, Andes; Ruokolainen, Kalle; Rutishauser, Ervan; Rutten, Gemma; Mohd Said, Mohd Nizam; Saiter, Felipe Z; Saner, Philippe; Santos, Braulio; Dos Santos, João Roberto; Sarker, Swapan Kumar; Schmitt, Christine B; Schoengart, Jochen; Schulze, Mark; Sheil, Douglas; Sist, Plinio; Souza, Alexandre F; Spironello, Wilson Roberto; Sposito, Tereza; Steinmetz, Robert; Stevart, Tariq; Suganuma, Marcio Seiji; Sukri, Rahayu; Sultana, Aisha; Sukumar, Raman; Sunderland, Terry; Supriyadi; Suresh, H S; Suzuki, Eizi; Tabarelli, Marcelo; Tang, Jianwei; Tanner, Ed V J; Targhetta, Natalia; Theilade, Ida; Thomas, Duncan; Timberlake, Jonathan; de Morisson Valeriano, Márcio; van Valkenburg, Johan; Van Do, Tran; Van Sam, Hoang; Vandermeer, John H; Verbeeck, Hans; Vetaas, Ole Reidar; Adekunle, Victor; Vieira, Simone A; Webb, Campbell O; Webb, Edward L; Whitfeld, Timothy; Wich, Serge; Williams, John; Wiser, Susan; Wittmann, Florian; Yang, Xiaobo; Adou Yao, C Yves; Yap, Sandra L; Zahawi, Rakan A; Zakaria, Rahmad; Zang, Runguo

2018-02-20

Knowledge about the biogeographic affinities of the world's tropical forests helps to better understand regional differences in forest structure, diversity, composition, and dynamics. Such understanding will enable anticipation of region-specific responses to global environmental change. Modern phylogenies, in combination with broad coverage of species inventory data, now allow for global biogeographic analyses that take species evolutionary distance into account. Here we present a classification of the world's tropical forests based on their phylogenetic similarity. We identify five principal floristic regions and their floristic relationships: ( i ) Indo-Pacific, ( ii ) Subtropical, ( iii ) African, ( iv ) American, and ( v ) Dry forests. Our results do not support the traditional neo- versus paleotropical forest division but instead separate the combined American and African forests from their Indo-Pacific counterparts. We also find indications for the existence of a global dry forest region, with representatives in America, Africa, Madagascar, and India. Additionally, a northern-hemisphere Subtropical forest region was identified with representatives in Asia and America, providing support for a link between Asian and American northern-hemisphere forests. Copyright © 2018 the Author(s). Published by PNAS.

Phylogenetic classification of the world’s tropical forests

PubMed Central

Franklin, Janet; Arroyo-Rodríguez, Víctor; Field, Richard; Aguilar, Salomon; Aguirre, Nikolay; Ahumada, Jorge; Aiba, Shin-Ichiro; K, Anitha; Avella, Andres; Mora, Francisco; Aymard C., Gerardo A.; Báez, Selene; Balvanera, Patricia; Bastian, Meredith L.; Bastin, Jean-François; Bellingham, Peter J.; van den Berg, Eduardo; da Conceição Bispo, Polyanna; Boeckx, Pascal; Boehning-Gaese, Katrin; Bongers, Frans; Boyle, Brad; Brearley, Francis Q.; Brown, Sandra; Chai, Shauna-Lee; Chazdon, Robin L.; Chen, Shengbin; Chhang, Phourin; Chuyong, George; Ewango, Corneille; Coronado, Indiana M.; Cristóbal-Azkarate, Jurgi; Culmsee, Heike; Damas, Kipiro; Dattaraja, H. S.; Davidar, Priya; DeWalt, Saara J.; Din, Hazimah; Drake, Donald R.; Durigan, Giselda; Eichhorn, Karl; Eler, Eduardo Schmidt; Enoki, Tsutomu; Ensslin, Andreas; Fandohan, Adandé Belarmain; Farwig, Nina; Feeley, Kenneth J.; Fischer, Markus; Forshed, Olle; Garcia, Queila Souza; Garkoti, Satish Chandra; Gillespie, Thomas W.; Gillet, Jean-Francois; Gonmadje, Christelle; Granzow-de la Cerda, Iñigo; Griffith, Daniel M.; Grogan, James; Hakeem, Khalid Rehman; Harris, David J.; Harrison, Rhett D.; Hector, Andy; Hemp, Andreas; Hussain, M. Shah; Ibarra-Manríquez, Guillermo; Hanum, I. Faridah; Imai, Nobuo; Jansen, Patrick A.; Joly, Carlos Alfredo; Joseph, Shijo; Kartawinata, Kuswata; Kearsley, Elizabeth; Kelly, Daniel L.; Kessler, Michael; Killeen, Timothy J.; Kooyman, Robert M.; Laumonier, Yves; Laurance, William F.; Lawes, Michael J.; Letcher, Susan G.; Lovett, Jon; Lozada, Jose; Lu, Xinghui; Lykke, Anne Mette; Mahmud, Khairil Bin; Mahayani, Ni Putu Diana; Mansor, Asyraf; Marshall, Andrew R.; Martin, Emanuel H.; Calderado Leal Matos, Darley; Meave, Jorge A.; Melo, Felipe P. L.; Mendoza, Zhofre Huberto Aguirre; Metali, Faizah; Medjibe, Vincent P.; Metzger, Jean Paul; Metzker, Thiago; Mohandass, D.; Munguía-Rosas, Miguel A.; Muñoz, Rodrigo; Nurtjahy, Eddy; de Oliveira, Eddie Lenza; Onrizal; Parolin, Pia; Parren, Marc; Parthasarathy, N.; Paudel, Ekananda; Perez, Rolando; Pérez-García, Eduardo A.; Pommer, Ulf; Poorter, Lourens; Qie, Lan; Piedade, Maria Teresa F.; Pinto, José Roberto Rodrigues; Poulsen, Axel Dalberg; Poulsen, John R.; Powers, Jennifer S.; Prasad, Rama Chandra; Puyravaud, Jean-Philippe; Rangel, Orlando; Reitsma, Jan; Rocha, Diogo S. B.; Rolim, Samir; Rovero, Francesco; Ruokolainen, Kalle; Rutishauser, Ervan; Rutten, Gemma; Mohd. Said, Mohd. Nizam; Saiter, Felipe Z.; Saner, Philippe; Santos, Braulio; dos Santos, João Roberto; Sarker, Swapan Kumar; Schoengart, Jochen; Schulze, Mark; Sheil, Douglas; Sist, Plinio; Souza, Alexandre F.; Spironello, Wilson Roberto; Sposito, Tereza; Steinmetz, Robert; Stevart, Tariq; Suganuma, Marcio Seiji; Sukri, Rahayu; Sukumar, Raman; Sunderland, Terry; Supriyadi; Suresh, H. S.; Suzuki, Eizi; Tabarelli, Marcelo; Tang, Jianwei; Tanner, Ed V. J.; Targhetta, Natalia; Theilade, Ida; Thomas, Duncan; Timberlake, Jonathan; de Morisson Valeriano, Márcio; van Valkenburg, Johan; Van Do, Tran; Van Sam, Hoang; Vandermeer, John H.; Verbeeck, Hans; Vetaas, Ole Reidar; Adekunle, Victor; Vieira, Simone A.; Webb, Campbell O.; Webb, Edward L.; Whitfeld, Timothy; Wich, Serge; Williams, John; Wiser, Susan; Wittmann, Florian; Yang, Xiaobo; Adou Yao, C. Yves; Yap, Sandra L.; Zahawi, Rakan A.; Zakaria, Rahmad; Zang, Runguo

2018-01-01

Knowledge about the biogeographic affinities of the world’s tropical forests helps to better understand regional differences in forest structure, diversity, composition, and dynamics. Such understanding will enable anticipation of region-specific responses to global environmental change. Modern phylogenies, in combination with broad coverage of species inventory data, now allow for global biogeographic analyses that take species evolutionary distance into account. Here we present a classification of the world’s tropical forests based on their phylogenetic similarity. We identify five principal floristic regions and their floristic relationships: (i) Indo-Pacific, (ii) Subtropical, (iii) African, (iv) American, and (v) Dry forests. Our results do not support the traditional neo- versus paleotropical forest division but instead separate the combined American and African forests from their Indo-Pacific counterparts. We also find indications for the existence of a global dry forest region, with representatives in America, Africa, Madagascar, and India. Additionally, a northern-hemisphere Subtropical forest region was identified with representatives in Asia and America, providing support for a link between Asian and American northern-hemisphere forests. PMID:29432167

Globalization and multi-spatial trends in the coverage of protected-area conservation (1980-2000).

PubMed

Zimmerer, Karl S; Galt, Ryan E; Buck, Margaret V

2004-12-01

This study is focused on the global expansion of protected-area coverage that occurred during the 1980--2000 period. We examine the multi-scale patterning of four of the basic facets of this expansion: i) estimated increases at the world-regional and country-level scales of total protected-area coverage; ii) transboundary protected areas; iii) conservation corridor projects; and iv) type of conservation management. Geospatial patterning of protected-area designations is a reflection of the priorities of global conservation organizations and the globalization of post-Cold War political and economic arrangements. Local and national-level factors (political leadership and infrastructure) as well as international relations such as multilateral and bilateral aid combine with these globalization processes to impact the extent, type, and location of protected-area designations. We conclude that the interaction of these factors led to the creation and reinforcement of marked spatial differences (rather than tendencies toward worldwide evenness or homogenization) in the course of protected-area expansion during the 1980--2000 period.

Historical record of Landsat global coverage

USGS Publications Warehouse

Goward, Samuel; Arvidson, Terry; Williams, Darrel; Faundeen, John; Irons, James; Franks, Shannon

2006-01-01

The long-term, 34+ year record of global Landsat remote sensing data is a critical resource to study the Earth system and human impacts on this system. The National Satellite Land Remote Sensing Data Archive (NSLRSDA) is charged by public law to: “maintain a permanent, comprehensive Government archive of global Landsat and other land remote sensing data for long-term monitoring and study of the changing global environment” (U.S. Congress, 1992). The advisory committee for NSLRSDA requested a detailed analysis of observation coverage within the U.S. Landsat holdings, as well as that acquired and held by International Cooperator (IC) stations. Our analyses, to date, have found gaps of varying magnitude in U.S. holdings of Landsat global coverage data, which appear to reflect technical or administrative variations in mission operations. In many cases it may be possible to partially fill these gaps in U.S. holdings through observations that were acquired and are now being held at International Cooperator stations.

Tertiary Institutions in Ghana Curriculum Coverage on Climate Change: Implications for Climate Change Awareness

ERIC Educational Resources Information Center

Boateng, C. A.

2015-01-01

Global problems such as climate change, which have deeper implications for survival of mankind on this planet, needs to be given wider attention in the quest for knowledge. It is expected that, improved knowledge derived from curriculum coverage may promote greater public awareness of such important global issue. This research aims at examining…

Global Moon Coverage via Hyperbolic Flybys

NASA Technical Reports Server (NTRS)

Buffington, Brent; Strange, Nathan; Campagnola, Stefano

2012-01-01

The scientific desire for global coverage of moons such as Jupiter's Galilean moons or Saturn's Titan has invariably led to the design of orbiter missions. These orbiter missions require a large amount of propellant needed to insert into orbit around such small bodies, and for a given launch vehicle, the additional propellant mass takes away from mass that could otherwise be used for scientific instrumentation on a multiple flyby-only mission. This paper will present methods--expanding upon techniques developed for the design of the Cassini prime and extended missions--to obtain near global moon coverage through multiple flybys. Furthermore we will show with proper instrument suite selection, a flyby-only mission can provide science return similar (and in some cases greater) to that of an orbiter mission.

"Perspectives on financing population-based health care towards Universal Health Coverage among employed individuals in Ghanzi district, Botswana: A qualitative study".

PubMed

Mbogo, Barnabas Africanus; McGill, Deborah

2016-08-19

Globally, about 150 million people experience catastrophic healthcare expenditure services annually. Among low and middle income countries, out-of-pocket expenditure pushes about 100 million people into poverty annually. In Botswana, 83 % of the general population and 58 % of employed individuals do not have medical aid coverage. Moreover, inequity allocation of financial resources between health services suggests marginalization of population-based health care services (i.e. diseases prevention and health promotion). The purpose of the study is to explore perspectives on employed individuals regarding financing population based health care interventions towards Universal Health Coverage (UHC) in order to make recommendations to the Ministry of Health on health financing options to cover population-based health services. A qualitative design grounded in interpretivist epistemology through social constructivism lens was critical for exploring perspectives of employed individuals. Through purposive and snowballing sampling techniques, a total of 15 respondents including 8 males and 7 females were recruited and interviewed using a semi-structured format. Their age ranged from 23 to 59 years with a median of 36 years. Data was analyzed using Thematic Content Analysis technique. Use of social constructivism lens enabled to classify emerging themes into population coverage, health services coverage and financial protection issues. Despite broad understanding of health coverage schemes among participants, knowledge appears insignificant in increasing enrolment. Participants indicated limited understanding of UHC concepts, however showed willingness to embrace UHC upon brief description. Main thematic issues raised include: exclusion of population-based health services from coverage scheme; disparity in financial protection and health services coverage among enrollees; inability to sustain contracted employees; and systematic exclusion of unemployed individuals and informal sector employees. Increasing enrolment in health coverage schemes requires targeted campaign for information dissemination through use of myriads mass media including: social networks, TV, Radio and others. Moreover, re-designing health insurance schemes is critical in order to include population-based interventions; expand uptake of unemployed and informal sector employees; flexibility in monthly premiums payment plan and use of technology to increase access to payment points. Further study need to evaluate the content of health financing policy in Botswana measured against the World Health Organization Universal Health Coverage conceptual requirements for Low and Middle Income Countries.

Global stability of a two-mediums rumor spreading model with media coverage

NASA Astrophysics Data System (ADS)

Huo, Liang'an; Wang, Li; Song, Guoxiang

2017-09-01

Rumor spreading is a typical form of social communication and plays a significant role in social life, and media coverage has a great influence on the spread of rumor. In this paper, we present a new model with two media coverage to investigate the impact of the different mediums on rumor spreading. Then, we calculate the equilibria of the model and construct the reproduction number ℜ0. And we prove the global asymptotic stability of equilibria by using Lyapunov functions. Finally, we can conclude that the transition rate of the ignorants between two mediums has a direct effect on the scale of spreaders, and different media coverage has significant effects on the dynamics behaviors of rumor spreading.

Mobile Technology for Empowering Health Workers in Underserved Communities: New Approaches to Facilitate the Elimination of Neglected Tropical Diseases.

PubMed

Stanton, Michelle; Molineux, Andrew; Mackenzie, Charles; Kelly-Hope, Louise

2016-01-01

As global mobile phone penetration increases, direct health information communication from hard-to-reach communities is becoming commonplace. Mobile health (mHealth) tools that enable disease control programs to benefit from this information, while simultaneously empowering community members to take control of their own health, are vital to the goal of universal health care. Our aim was to highlight the development of the Liverpool mHealth Suite (LMS), which has been designed to address this need and improve health services for neglected tropical diseases being targeted for global elimination, such as lymphatic filariasis. The LMS has two main communication approaches-short message service and mobile phone apps-to facilitate real-time mass drug administration (MDA) coverage, reporting patient numbers, managing stock levels of treatment supplies, and exchanging health information to improve the quality of care of those affected. The LMS includes the MeasureSMS-MDA tool to improve drug supplies and MDA coverage rates in real-time (currently being trialed in urban Tanzania); the MeasureSMS-Morbidity tool to map morbidity, including lymphedema and hydrocele cases (initially piloted in rural Malawi and Ghana, then extended to Ethiopia, and scaled up to large urban areas in Bangladesh and Tanzania); the LyMSS-lymphedema management supply system app to improve distribution of treatments (trialed for 6 months in Malawi with positive impacts on health workers and patients); and the HealthFront app to improve education and training (in development with field trials planned). The current success and scale-up of the LMS by many community health workers in rural and urban settings across Africa and Asia highlights the value of this simple and practical suite of tools that empowers local health care workers to contribute to local, national, and global elimination of disease.

Development of the Double Etalon Fabry-Perot Interferometer for Determining Total and Tropospheric Ozone Concentrations

NASA Technical Reports Server (NTRS)

Cook, William

1999-01-01

Measuring and understanding the distribution of ozone through the lower levels of Earth's atmosphere are high priorities in global change and climate research. Of particular interest now is the global distribution of ozone in the upper troposphere and lower stratosphere. Global coverage of the stratospheric ozone is feasible only via remote sensing instruments on a space-based platform. And though extensive monitoring tropospheric ozone is possible using instruments flown aboard conventional aircraft, a space-based system would be significantly less costly and provide information over a much broader area and produce more uniform coverage. Here we describe the prototype of an instrument being developed to monitor, from an orbiting spacecraft, the ozone found in Earth's upper troposphere and lower stratosphere. Our new spectrometer is an infrared Fabry-Perot interferometer which uses two synchrounously tuned etalons: a high resolution narrow band device and a lower resolution broader band filtering etalon. The prototype is a scanning device making use of nearly collimated input radiation and a single element detector. As presently configured, it is capable of providing a resolution better than 0.07/cm with a spectral band width approximately 5/cm wide and centered at 1054.7/cm. For the future space-based emission device a modification of the the prototype was to be made to employ innovative circle-to-line detector optics, those developed or in development at UM/SPRL, and a focal plane array detector. These enhancements would enable a simultaneous recording of the entire spectral range of interest, but with simple detection electronics and a significant gain in signal-to-noise over that of the scanning version.

Global Coastal and Marine Spatial Planning (CMSP) from Space Based AIS Ship Tracking

NASA Astrophysics Data System (ADS)

Schwehr, K. D.; Foulkes, J. A.; Lorenzini, D.; Kanawati, M.

2011-12-01

All nations need to be developing long term integrated strategies for how to use and preserve our natural resources. As a part of these strategies, we must evalutate how communities of users react to changes in rules and regulations of ocean use. Global characterization of the vessel traffic on our Earth's oceans is essential to understanding the existing uses to develop international Coast and Marine Spatial Planning (CMSP). Ship traffic within 100-200km is beginning to be effectively covered in low latitudes by ground based receivers collecting position reports from the maritime Automatic Identification System (AIS). Unfortunately, remote islands, high latitudes, and open ocean Marine Protected Areas (MPA) are not covered by these ground systems. Deploying enough autonomous airborne (UAV) and surface (USV) vessels and buoys to provide adequate coverage is a difficult task. While the individual device costs are plummeting, a large fleet of AIS receivers is expensive to maintain. The global AIS coverage from SpaceQuest's low Earth orbit satellite receivers combined with the visualization and data storage infrastructure of Google (e.g. Maps, Earth, and Fusion Tables) provide a platform that enables researchers and resource managers to begin answer the question of how ocean resources are being utilized. Near real-time vessel traffic data will allow managers of marine resources to understand how changes to education, enforcement, rules, and regulations alter usage and compliance patterns. We will demonstrate the potential for this system using a sample SpaceQuest data set processed with libais which stores the results in a Fusion Table. From there, the data is imported to PyKML and visualized in Google Earth with a custom gx:Track visualization utilizing KML's extended data functionality to facilitate ship track interrogation. Analysts can then annotate and discuss vessel tracks in Fusion Tables.

Operational Interoperable Web Coverage Service for Earth Observing Satellite Data: Issues and Lessons Learned

NASA Astrophysics Data System (ADS)

Yang, W.; Min, M.; Bai, Y.; Lynnes, C.; Holloway, D.; Enloe, Y.; di, L.

2008-12-01

In the past few years, there have been growing interests, among major earth observing satellite (EOS) data providers, in serving data through the interoperable Web Coverage Service (WCS) interface protocol, developed by the Open Geospatial Consortium (OGC). The interface protocol defined in WCS specifications allows client software to make customized requests of multi-dimensional EOS data, including spatial and temporal subsetting, resampling and interpolation, and coordinate reference system (CRS) transformation. A WCS server describes an offered coverage, i.e., a data product, through a response to a client's DescribeCoverage request. The description includes the offered coverage's spatial/temporal extents and resolutions, supported CRSs, supported interpolation methods, and supported encoding formats. Based on such information, a client can request the entire or a subset of coverage in any spatial/temporal resolutions and in any one of the supported CRSs, formats, and interpolation methods. When implementing a WCS server, a data provider has different approaches to present its data holdings to clients. One of the most straightforward, and commonly used, approaches is to offer individual physical data files as separate coverages. Such implementation, however, will result in too many offered coverages for large data holdings and it also cannot fully present the relationship among different, but spatially and/or temporally associated, data files. It is desirable to disconnect offered coverages from physical data files so that the former is more coherent, especially in spatial and temporal domains. Therefore, some servers offer one single coverage for a set of spatially coregistered time series data files such as a daily global precipitation coverage linked to many global single- day precipitation files; others offer one single coverage for multiple temporally coregistered files together forming a large spatial extent. In either case, a server needs to assemble an output coverage real-time by combining potentially large number of physical files, which can be operationally difficult. The task becomes more challenging if an offered coverage involves spatially and temporally un-registered physical files. In this presentation, we will discuss issues and lessons learned in providing NASA's AIRS Level 2 atmospheric products, which are in satellite swath CRS and in 6-minute segment granule files, as virtual global coverages. We"ll discuss the WCS server's on- the-fly georectification, mosaicking, quality screening, performance, and scalability.

SweepSAR Sensor Technology for Dense Spatial and Temporal Coverage of Earth Change

NASA Astrophysics Data System (ADS)

Rosen, P. A.

2016-12-01

Since the 2007 National Academy of Science "Decadal Survey" report, NASA has been studying concepts for a Synthetic Aperture Radar (SAR) mission to determine Earth change in three disciplines - ecosystems, solid earth, and cryospheric sciences. NASA has joined forces with the Indian Space Research Organisation (ISRO) to fulfill these objectives. The NASA-ISRO SAR (NISAR) mission is now in development for a launch in 2021. The mission's primary science objectives are codified in a set of science requirements to study Earth land and ice deformation, and ecosystems, globally with 12-day sampling over all land and ice-covered surfaces throughout the mission life. The US and Indian science teams share global science objectives; in addition, India has developed a set of local objectives in agricultural biomass estimation, Himalayan glacier characterization, and coastal ocean measurements in and around India. Both the US and India have identified agricultural and infrastructure monitoring, and disaster response as high priority applications for the mission. With this range of science and applications objectives, NISAR has demanding coverage, sampling, and accuracy requirements. The system requires a swath of over 240 km at 3-10 m SAR imaging resolution, using full polarimetry where needed. Given the broad range of phenomena and wide range of sensitivities needed, NISAR carries two radars, one operating at L-band (24 cm wavelength) and the other at S-band (10 cm wavelength). The system uses a new "scan-on-receive" ("SweepSAR") technology at both L-band and S-band, that enables full swath coverage without loss of resolution or polarimetric diversity. Both radars can operate simultaneously. The L-band system is being designed to operate up to 50 minutes per orbit, and the S-band system up to 10 minutes per orbit. The orbit will be controlled to within 300 m for repeat-pass interferometry measurements. This unprecedented coverage in space, time, polarimetry, and frequency, will add a new and rich data set to the international constellation of sensors studying Earth surface change. In this talk, we will describe the mission's expected contributions to geodetic imaging in support of time-series analysis of dynamic changes of Earth's surface.

Global, quantitative and dynamic mapping of protein subcellular localization

PubMed Central

Itzhak, Daniel N; Tyanova, Stefka; Cox, Jürgen; Borner, Georg HH

2016-01-01

Subcellular localization critically influences protein function, and cells control protein localization to regulate biological processes. We have developed and applied Dynamic Organellar Maps, a proteomic method that allows global mapping of protein translocation events. We initially used maps statically to generate a database with localization and absolute copy number information for over 8700 proteins from HeLa cells, approaching comprehensive coverage. All major organelles were resolved, with exceptional prediction accuracy (estimated at >92%). Combining spatial and abundance information yielded an unprecedented quantitative view of HeLa cell anatomy and organellar composition, at the protein level. We subsequently demonstrated the dynamic capabilities of the approach by capturing translocation events following EGF stimulation, which we integrated into a quantitative model. Dynamic Organellar Maps enable the proteome-wide analysis of physiological protein movements, without requiring any reagents specific to the investigated process, and will thus be widely applicable in cell biology. DOI: http://dx.doi.org/10.7554/eLife.16950.001 PMID:27278775

Combined Landsat-8 and Sentinel-2 Burned Area Mapping

NASA Astrophysics Data System (ADS)

Huang, H.; Roy, D. P.; Zhang, H.; Boschetti, L.; Yan, L.; Li, Z.

2017-12-01

Fire products derived from coarse spatial resolution satellite data have become an important source of information for the multiple user communities involved in fire science and applications. The advent of the MODIS on NASA's Terra and Aqua satellites enabled systematic production of 500m global burned area maps. There is, however, an unequivocal demand for systematically generated higher spatial resolution burned area products, in particular to examine the role of small-fires for various applications. Moderate spatial resolution contemporaneous satellite data from Landsat-8 and the Sentinel-2A and -2B sensors provide the opportunity for detailed spatial mapping of burned areas. Combined, these polar-orbiting systems provide 10m to 30m multi-spectral global coverage more than once every three days. This NASA funded research presents results to prototype a combined Landsat-8 Sentinel-2 burned area product. The Landsat-8 and Sentinel-2 pre-processing, the time-series burned area mapping algorithm, and preliminary results and validation using high spatial resolution commercial satellite data over Africa are presented.

Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) Overview

USGS Publications Warehouse

,

2008-01-01

The National Aeronautics and Space Administration (NASA) launched Terra, the Earth Observing System's (EOS) flagship satellite platform on December 18, 1999. The polar-orbiting Terra contains five remote sensing instruments, which enable the scientific study and analyses of global terrestrial processes and manifestations of global change. One of the five instruments is the multispectral Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER), which is built in Japan by a consortium of government, industry, and research groups. It has three spectral bands in the visible near-infrared region (VNIR), six bands in the shortwave infrared region (SWIR), and five bands in the thermal infrared region (TIR), with 15-, 30-, and 90-meter ground resolutions, respectively. This combination of wide spectral coverage and high spatial resolution allows ASTER to discriminate among a wide variety of surface materials. The VNIR subsystem also has a backward-viewing telescope for high-resolution (15-meter) stereoscopic observation in the along-track direction, which facilitates the generation of digital elevation models (DEM).

Image reconstruction and scan configurations enabled by optimization-based algorithms in multispectral CT

NASA Astrophysics Data System (ADS)

Chen, Buxin; Zhang, Zheng; Sidky, Emil Y.; Xia, Dan; Pan, Xiaochuan

2017-11-01

Optimization-based algorithms for image reconstruction in multispectral (or photon-counting) computed tomography (MCT) remains a topic of active research. The challenge of optimization-based image reconstruction in MCT stems from the inherently non-linear data model that can lead to a non-convex optimization program for which no mathematically exact solver seems to exist for achieving globally optimal solutions. In this work, based upon a non-linear data model, we design a non-convex optimization program, derive its first-order-optimality conditions, and propose an algorithm to solve the program for image reconstruction in MCT. In addition to consideration of image reconstruction for the standard scan configuration, the emphasis is on investigating the algorithm’s potential for enabling non-standard scan configurations with no or minimum hardware modification to existing CT systems, which has potential practical implications for lowered hardware cost, enhanced scanning flexibility, and reduced imaging dose/time in MCT. Numerical studies are carried out for verification of the algorithm and its implementation, and for a preliminary demonstration and characterization of the algorithm in reconstructing images and in enabling non-standard configurations with varying scanning angular range and/or x-ray illumination coverage in MCT.

Football's coming home?: Digital reterritorialization, contradictions in the transnational coverage of sport and the sociology of alternative football broadcasts.

PubMed

David, Matthew; Millward, Peter

2012-06-01

This article critically utilizes the work of Manuel Castells to discuss the issue of parallel imported broadcasts (specifically including live-streams) in football. This is of crucial importance to sport because the English Premier League is premised upon the sale of television rights broadcasts to domestic and overseas markets, and yet cheaper alternative broadcasts endanger the price of such rights. Evidence is drawn from qualitative fieldwork and library/Internet sources to explore the practices of supporters and the politics involved in the generation of alternative broadcasts. This enables us to clarify the core sociological themes of 'milieu of innovation' and 'locale' within today's digitally networked global society. © London School of Economics and Political Science 2012.

On-Board Switching and Routing Advanced Technology Study

NASA Technical Reports Server (NTRS)

Yegenoglu, F.; Inukai, T.; Kaplan, T.; Redman, W.; Mitchell, C.

1998-01-01

Future satellite communications is expected to be fully integrated into National and Global Information Infrastructures (NII/GII). These infrastructures will carry multi gigabit-per-second data rates, with integral switching and routing of constituent data elements. The satellite portion of these infrastructures must, therefore, be more than pipes through the sky. The satellite portion will also be required to perform very high speed routing and switching of these data elements to enable efficient broad area coverage to many home and corporate users. The technology to achieve the on-board switching and routing must be selected and developed specifically for satellite application within the next few years. This report presents evaluation of potential technologies for on-board switching and routing applications.

From blockchain technology to global health equity: can cryptocurrencies finance universal health coverage?

PubMed

Till, Brian M; Peters, Alexander W; Afshar, Salim; Meara, John

2017-01-01

Blockchain technology and cryptocurrencies could remake global health financing and usher in an era global health equity and universal health coverage. We outline and provide examples for at least four important ways in which this potential disruption of traditional global health funding mechanisms could occur: universal access to financing through direct transactions without third parties; novel new multilateral financing mechanisms; increased security and reduced fraud and corruption; and the opportunity for open markets for healthcare data that drive discovery and innovation. We see these issues as a paramount to the delivery of healthcare worldwide and relevant for payers and providers of healthcare at state, national and global levels; for government and non-governmental organisations; and for global aid organisations, including the WHO, International Monetary Fund and World Bank Group.

Case studies of innovative medical device companies from India: barriers and enablers to development

PubMed Central

2013-01-01

Background Over 75% of the medical devices used in India are imported. Often, they are costly and maladapted to low-resource settings. We have prepared case studies of six firms in Bangalore that could contribute to solving this problem. They have developed (or are developing) innovative health care products and therefore are pioneers in the Indian health care sector, better known for its reverse engineering skills. We have sought to understand what enablers and barriers they encountered. Methods Information for the case studies was collected through semi-structured interviews. Initially, over 40 stakeholders of the diagnostics sector in India were interviewed to understand the sector. However the focus here is on the six featured companies. Further information was obtained from company material and other published resources. Results In all cases, product innovation has been enabled by close interaction with local medical practitioners, links to global science and technology and global regulatory requirements. The major challenges were the lack of guidance on product specifications from the national regulatory agency, paucity of institutionalized health care payers and lack of transparency and formalized Health Technology Assessment in coverage decision-making. The absence of national evidence-based guidelines and of compulsory continuous education for medical practitioners were key obstacles in accessing the poorly regulated and fragmented private market. Conclusions Innovative Indian companies would benefit from a strengthened capacity and interdisciplinary work culture of the national device regulatory body, institutionalized health care payers and medical councils and associations. Continuous medical education and national medical guidelines for medical practitioners would facilitate market access for innovative products. PMID:23721110

Case studies of innovative medical device companies from India: barriers and enablers to development.

PubMed

Jarosławski, Szymon; Saberwal, Gayatri

2013-05-30

Over 75% of the medical devices used in India are imported. Often, they are costly and maladapted to low-resource settings. We have prepared case studies of six firms in Bangalore that could contribute to solving this problem. They have developed (or are developing) innovative health care products and therefore are pioneers in the Indian health care sector, better known for its reverse engineering skills. We have sought to understand what enablers and barriers they encountered. Information for the case studies was collected through semi-structured interviews. Initially, over 40 stakeholders of the diagnostics sector in India were interviewed to understand the sector. However the focus here is on the six featured companies. Further information was obtained from company material and other published resources. In all cases, product innovation has been enabled by close interaction with local medical practitioners, links to global science and technology and global regulatory requirements. The major challenges were the lack of guidance on product specifications from the national regulatory agency, paucity of institutionalized health care payers and lack of transparency and formalized Health Technology Assessment in coverage decision-making. The absence of national evidence-based guidelines and of compulsory continuous education for medical practitioners were key obstacles in accessing the poorly regulated and fragmented private market. Innovative Indian companies would benefit from a strengthened capacity and interdisciplinary work culture of the national device regulatory body, institutionalized health care payers and medical councils and associations. Continuous medical education and national medical guidelines for medical practitioners would facilitate market access for innovative products.

Developing a Scorecard to Assess Global Progress in Scaling Up Diarrhea Control Tools: A Qualitative Study of Academic Leaders and Implementers

PubMed Central

Rosinski, Alexander Anthony; Narine, Steven; Yamey, Gavin

2013-01-01

Background In 2010, diarrhea caused 0.75 million child deaths, accounting for nearly 12% of all under-five mortality worldwide. Many evidence-based interventions can reduce diarrhea mortality, including oral rehydration solution (ORS), zinc, and improved sanitation. Yet global coverage levels of such interventions remain low. A new scorecard of diarrhea control, showing how different countries are performing in their control efforts, could draw greater attention to the low coverage levels of proven interventions. Methods We conducted in-depth qualitative interviews with 21 experts, purposively sampled for their relevant academic or implementation expertise, to explore their views on (a) the value of a scorecard of global diarrhea control and (b) which indicators should be included in such a scorecard. We then conducted a ranking exercise in which we compiled a list of all 49 indicators suggested by the experts, sent the list to the 21 experts, and asked them to choose 10 indicators that they would include and 10 that they would exclude from such a scorecard. Finally, we created a “prototype” scorecard based on the 9 highest-ranked indicators. Results Key themes that emerged from coding the interview transcripts were: a scorecard could facilitate country comparisons; it could help to identify best practices, set priorities, and spur donor action; and it could help with goal-setting and accountability in diarrhea control. The nine highest ranking indicators, in descending order, were ORS coverage, rotavirus vaccine coverage, zinc coverage, diarrhea-specific mortality rate, diarrhea prevalence, proportion of population with access to improved sanitation, proportion with access to improved drinking water, exclusive breastfeeding coverage, and measles vaccine coverage. Conclusion A new scorecard of global diarrhea control could help track progress, focus prevention and treatment efforts on the most effective interventions, establish transparency and accountability, and alert donors and ministries of health to inadequacies in diarrhea control efforts. PMID:23874412

Global precipitation measurement (GPM) preliminary design

NASA Astrophysics Data System (ADS)

Neeck, Steven P.; Kakar, Ramesh K.; Azarbarzin, Ardeshir A.; Hou, Arthur Y.

2008-10-01

The overarching Earth science mission objective of the Global Precipitation Measurement (GPM) mission is to develop a scientific understanding of the Earth system and its response to natural and human-induced changes. This will enable improved prediction of climate, weather, and natural hazards for present and future generations. The specific scientific objectives of GPM are advancing: Precipitation Measurement through combined use of active and passive remote-sensing techniques, Water/Energy Cycle Variability through improved knowledge of the global water/energy cycle and fresh water availability, Climate Prediction through better understanding of surface water fluxes, soil moisture storage, cloud/precipitation microphysics and latent heat release, Weather Prediction through improved numerical weather prediction (NWP) skills from more accurate and frequent measurements of instantaneous rain rates with better error characterizations and improved assimilation methods, Hydrometeorological Prediction through better temporal sampling and spatial coverage of highresolution precipitation measurements and innovative hydro-meteorological modeling. GPM is a joint initiative with the Japan Aerospace Exploration Agency (JAXA) and other international partners and is the backbone of the Committee on Earth Observation Satellites (CEOS) Precipitation Constellation. It will unify and improve global precipitation measurements from a constellation of dedicated and operational active/passive microwave sensors. GPM is completing the Preliminary Design Phase and is advancing towards launch in 2013 and 2014.

2013 - JPL's Snow Data System Year in Review

NASA Astrophysics Data System (ADS)

Goodale, C. E.; Painter, T. H.; Mattmann, C. A.; Brodzik, M.; Rittger, K. E.; Burgess, A.

2013-12-01

2013 has been a big year for JPL's Snow Data Processing System. This year our efforts have been focused on supporting the Colorado Basin River Forecast Center, working on products in the Western United States and Alaska for the National Climate Assessment, as well as research efforts in the Hindu Kush Himalaya Region of Asia through the generation and publication of our MODSCAG, MODDRFS and MODICE products. We have revisited the processing stream for our snow properties products as we expand to global coverage providing a higher quality, consistent dataset. We have enabled lossless compression as well as using more efficient data types for our data arrays. This has enabled our archive to expand its coverage while conserving disk space, which comes with the added benefit of making the data downloads smaller and faster. Storage and compression aren't the only changes we have made; there have also been several improvements with cloud masking and missing data identification. These improvements have resulted in products that are smaller and more concise. Our source for MOD09GA data is the LP.DAAC. In June of this year the DAAC switched from an FTP server to HTTP. Our team has been able to adapt to this change by using NASA's ECHO Catalog to search for links to download the MOD09GA HDF files our processing pipeline uses to create the SCAG and DRFS products. We looked at using Reverb, but they limit the search results to only 2000 granules, where our typical granule count for a single tile exceeds 4000. We would like to share our improvements to the output products, the lessons we learned from the DAAC changing to HTTP and how others can learn from us, and share the tools we have created. Our plan is to also show our current archive coverage of products, and where we will are planning to process data in 2014 and beyond.

Multisatellite systems with linear structure and their application for continuous coverage of the earth

NASA Astrophysics Data System (ADS)

Saulskiy, V. K.

2005-01-01

Multisatellite systems with linear structure (SLS) are defined, and their application for a continuous global or zonal coverage of the Earth’s surface is justified. It is demonstrated that in some cases these systems turned out to be better than usually recommended kinematically regular systems by G.V. Mozhaev, delta systems of J.G. Walker, and polar systems suggested by F.W. Gobets, L. Rider, and W.S. Adams. When a comparison is made using the criterion of a minimum radius of one-satellite coverage circle, the SLS beat the other systems for the majority of satellite numbers from the range 20 63, if the global continuous single coverage of the Earth is required. In the case of a zonal continuous single coverage of the latitude belt ±65°, the SLS are preferable at almost all numbers of satellites from 38 to 100, and further at any values up to 200 excluding 144.

Teaching Tectonics to Undergraduates with Web GIS

NASA Astrophysics Data System (ADS)

Anastasio, D. J.; Bodzin, A.; Sahagian, D. L.; Rutzmoser, S.

2013-12-01

Geospatial reasoning skills provide a means for manipulating, interpreting, and explaining structured information and are involved in higher-order cognitive processes that include problem solving and decision-making. Appropriately designed tools, technologies, and curriculum can support spatial learning. We present Web-based visualization and analysis tools developed with Javascript APIs to enhance tectonic curricula while promoting geospatial thinking and scientific inquiry. The Web GIS interface integrates graphics, multimedia, and animations that allow users to explore and discover geospatial patterns that are not easily recognized. Features include a swipe tool that enables users to see underneath layers, query tools useful in exploration of earthquake and volcano data sets, a subduction and elevation profile tool which facilitates visualization between map and cross-sectional views, drafting tools, a location function, and interactive image dragging functionality on the Web GIS. The Web GIS platform is independent and can be implemented on tablets or computers. The GIS tool set enables learners to view, manipulate, and analyze rich data sets from local to global scales, including such data as geology, population, heat flow, land cover, seismic hazards, fault zones, continental boundaries, and elevation using two- and three- dimensional visualization and analytical software. Coverages which allow users to explore plate boundaries and global heat flow processes aided learning in a Lehigh University Earth and environmental science Structural Geology and Tectonics class and are freely available on the Web.

Operational satellites and the global monitoring of snow and ice

NASA Technical Reports Server (NTRS)

Walsh, John E.

1991-01-01

The altitudinal dependence of the global warming projected by global climate models is at least partially attributable to the albedo-temperature feedback involving snow and ice, which must be regarded as key variables in the monitoring for global change. Statistical analyses of data from IR and microwave sensors monitoring the areal coverage and extent of sea ice have led to mixed conclusions about recent trends of hemisphere sea ice coverage. Seasonal snow cover has been mapped for over 20 years by NOAA/NESDIS on the basis of imagery from a variety of satellite sensors. Multichannel passive microwave data show some promise for the routine monitoring of snow depth over unforested land areas.

SSE Global Data

Atmospheric Science Data Center

2018-04-12

SSE Global Data Text files of monthly averaged data for the entire ... Version:  V6 Location:  Global Spatial Coverage:  (90N, 90S)(180W,180E) ... File Format:  ASCII Order Data:  SSE Global Data: Order Data SCAR-B Block:  ...

From blockchain technology to global health equity: can cryptocurrencies finance universal health coverage?

PubMed Central

Till, Brian M; Peters, Alexander W; Afshar, Salim; Meara, John G

2017-01-01

Blockchain technology and cryptocurrencies could remake global health financing and usher in an era global health equity and universal health coverage. We outline and provide examples for at least four important ways in which this potential disruption of traditional global health funding mechanisms could occur: universal access to financing through direct transactions without third parties; novel new multilateral financing mechanisms; increased security and reduced fraud and corruption; and the opportunity for open markets for healthcare data that drive discovery and innovation. We see these issues as a paramount to the delivery of healthcare worldwide and relevant for payers and providers of healthcare at state, national and global levels; for government and non-governmental organisations; and for global aid organisations, including the WHO, International Monetary Fund and World Bank Group. PMID:29177101

State of equity: childhood immunization in the World Health Organization African Region.

PubMed

Casey, Rebecca Mary; Hampton, Lee McCalla; Anya, Blanche-Philomene Melanga; Gacic-Dobo, Marta; Diallo, Mamadou Saliou; Wallace, Aaron Stuart

2017-01-01

In 2010, the Global Vaccine Action Plan called on all countries to reach and sustain 90% national coverage and 80% coverage in all districts for the third dose of diphtheria-tetanus-pertussis vaccine (DTP3) by 2015 and for all vaccines in national immunization schedules by 2020. The aims of this study are to analyze recent trends in national vaccination coverage in the World Health Organization African Region andto assess how these trends differ by country income category. We compared national vaccination coverage estimates for DTP3 and the first dose of measles-containing vaccine (MCV) obtained from the World Health Organization (WHO)/United Nations Children's Fund (UNICEF) joint estimates of national immunization coverage for all African Region countries. Using United Nations (UN) population estimates of surviving infants and country income category for the corresponding year, we calculated population-weighted average vaccination coverage by country income category (i.e., low, lower middle, and upper middle-income) for the years 2000, 2005, 2010 and 2015. DTP3 coverage in the African Region increased from 52% in 2000 to 76% in 2015,and MCV1 coverage increased from 53% to 74% during the same period, but with considerable differences among countries. Thirty-six African Region countries were low income in 2000 with an average DTP3 coverage of 50% while 26 were low income in 2015 with an average coverage of 80%. Five countries were lower middle-income in 2000 with an average DTP3 coverage of 84% while 12 were lower middle-income in 2015 with an average coverage of 69%. Five countries were upper middle-income in 2000 with an average DTP3 coverage of 73% and eight were upper middle-income in 2015 with an average coverage of 76%. Disparities in vaccination coverage by country persist in the African Region, with countries that were lower middle-income having the lowest coverage on average in 2015. Monitoring and addressing these disparities is essential for meeting global immunization targets.

Implications of MOLA Global Roughness, Statistics, and Topography

NASA Technical Reports Server (NTRS)

Aharonson, O.; Zuber, M. T.; Neumann, G. A.

1999-01-01

New insights are emerging as the ongoing high-quality measurements of the Martian surface topography by Mars Orbiter Laser Altimeter (MOLA) on board the Mars Global Surveyor (MGS) spacecraft increase in coverage, resolution, and diversity. For the first time, a global characterization of the statistical properties of topography is possible. The data were collected during the aerobreaking hiatus, science phasing, and mapping orbits of MGS, and have a resolution of 300-400 m along track, a range resolution of 37.5 cm, a range precision of 1-10 m for surface slopes up to 30 deg., and an absolute accuracy of topography of 13 m. The spacecraft's orbit inclination dictates that nadir observations have latitude coverage of about 87.1S to 87.1N; the addition of observations obtained during a period of off-nadir pointing over the north pole extended coverage to 90N. Additional information is contained in the original extended abstract.

Reconstruction of Arctic surface temperature in past 100 years using DINEOF

NASA Astrophysics Data System (ADS)

Zhang, Qiyi; Huang, Jianbin; Luo, Yong

2015-04-01

Global annual mean surface temperature has not risen apparently since 1998, which is described as global warming hiatus in recent years. However, measuring of temperature variability in Arctic is difficult because of large gaps in coverage of Arctic region in most observed gridded datasets. Since Arctic has experienced a rapid temperature change in recent years that called polar amplification, and temperature risen in Arctic is faster than global mean, the unobserved temperature in central Arctic will result in cold bias in both global and Arctic temperature measurement compared with model simulations and reanalysis datasets. Moreover, some datasets that have complete coverage in Arctic but short temporal scale cannot show Arctic temperature variability for long time. Data Interpolating Empirical Orthogonal Function (DINEOF) were applied to fill the coverage gap of NASA's Goddard Institute for Space Studies Surface Temperature Analysis (GISTEMP 250km smooth) product in Arctic with IABP dataset which covers entire Arctic region between 1979 and 1998, and to reconstruct Arctic temperature in 1900-2012. This method provided temperature reconstruction in central Arctic and precise estimation of both global and Arctic temperature variability with a long temporal scale. Results have been verified by extra independent station records in Arctic by statistical analysis, such as variance and standard deviation. The result of reconstruction shows significant warming trend in Arctic in recent 30 years, as the temperature trend in Arctic since 1997 is 0.76°C per decade, compared with 0.48°C and 0.67°C per decade from 250km smooth and 1200km smooth of GISTEMP. And global temperature trend is two times greater after using DINEOF. The discrepancies above stress the importance of fully consideration of temperature variance in Arctic because gaps of coverage in Arctic cause apparent cold bias in temperature estimation. The result of global surface temperature also proves that global warming in recent years is not as slow as thought.

Enabling Technologies for High-accuracy Multiangle Spectropolarimetric Imaging from Space

NASA Technical Reports Server (NTRS)

Diner, David J.; Macenka, Steven A.; Seshndri, Suresh; Bruce, Carl E; Jau, Bruno; Chipman, Russell A.; Cairns, Brian; Christoph, Keller; Foo, Leslie D.

2004-01-01

Satellite remote sensing plays a major role in measuring the optical and radiative properties, environmental impact, and spatial and temporal distribution of tropospheric aerosols. In this paper, we envision a new generation of spaceborne imager that integrates the unique strengths of multispectral, multiangle, and polarimetric approaches, thereby achieving better accuracies in aerosol optical depth and particle properties than can be achieved using any one method by itself. Design goals include spectral coverage from the near-UV to the shortwave infrared; global coverage within a few days; intensity and polarimetric imaging simultaneously at multiple view angles; kilometer to sub-kilometer spatial resolution; and measurement of the degree of linear polarization for a subset of the spectral complement with an uncertainty of 0.5% or less. The latter requirement is technically the most challenging. In particular, an approach for dealing with inter-detector gain variations is essential to avoid false polarization signals. We propose using rapid modulation of the input polarization state to overcome this problem, using a high-speed variable retarder in the camera design. Technologies for rapid retardance modulation include mechanically rotating retarders, liquid crystals, and photoelastic modulators (PEMs). We conclude that the latter are the most suitable.

The need of adequate information to achieve total compliance of mass drug administration in Pekalongan

NASA Astrophysics Data System (ADS)

Ginandjar, Praba; Saraswati, Lintang Dian; Taufik, Opik; Nurjazuli; Widjanarko, Bagoes

2017-02-01

World Health Organization (WHO) initiated The Global Program to Eliminate Lymphatic Filariasis (LF) through mass drug administration (MDA). Pekalongan started MDA in 2011. Yet the LF prevalence in 2015 remained exceed the threshold (1%). This study aimed to describe the inhibiting factors related to the compliance of MDA in community level. This was a rapid survey with cross sectional approach. A two-stages random sampling was used in this study. In the first stage, 25 clusters were randomly selected from 27 villages with proportionate to population size (PPS) methods (C-Survey). In the second stage, 10 subjects were randomly selected from each cluster. Subject consisted of 250 respondents from 25 selected clusters. Variables consisted of MDA coverage, practice of taking medication during MDA, enabling and inhibiting factors to MDA in community level. The results showed most respondents had poor knowledge on filariasis, which influence awareness of the disease. Health-illness perception, did not receive the drugs, lactation, side effect, and size of the drugs were dominant factors of non-compliance to MDA. MDA information and community empowerment were needed to improve MDA coverage. Further study to explore the appropriate model of socialization will support the success of MDA program

Exploring vegetation in the fourth dimension.

PubMed

Mitchell, Fraser J G

2011-01-01

Much ecological research focuses on changes in vegetation on spatial scales from stands to landscapes; however, capturing data on vegetation change over relevant timescales remains a challenge. Pollen analysis offers unrivalled access to data with global coverage over long timescales. Robust techniques have now been developed that enable pollen data to be converted into vegetation data in terms of individual taxa, plant communities or biomes, with the possibility of deriving from those data a range of plant attributes and ecological indicators. In this review, I discuss how coupling pollen with macrofossil, charcoal and genetic data opens up the extensive pollen databases to investigation of the drivers of vegetation change over time and also provides extensive data sets for testing hypotheses with wide ecological relevance. © 2010 Elsevier Ltd. All rights reserved.

The Politics of Universal Health Coverage in Low- and Middle-Income Countries: A Framework for Evaluation and Action.

PubMed

Fox, Ashley M; Reich, Michael R

2015-10-01

Universal health coverage has recently become a top item on the global health agenda pressed by multilateral and donor organizations, as disenchantment grows with vertical, disease-specific health programs. This increasing focus on universal health coverage has brought renewed attention to the role of domestic politics and the interaction between domestic and international relations in the health reform process. This article proposes a theory-based framework for analyzing the politics of health reform for universal health coverage, according to four stages in the policy cycle (agenda setting, design, adoption, and implementation) and four variables that affect reform (interests, institutions, ideas, and ideology). This framework can assist global health policy researchers, multilateral organization officials, and national policy makers in navigating the complex political waters of health reforms aimed at achieving universal health coverage. To derive the framework, we critically review the theoretical and applied literature on health policy reform in developing countries and illustrate the framework with examples of health reforms moving toward universal coverage in low- and middle-income countries. We offer a series of lessons stemming from these experiences to date. Copyright © 2015 by Duke University Press.

JADDS - towards a tailored global atmospheric composition data service for CAMS forecasts and reanalysis

NASA Astrophysics Data System (ADS)

Stein, Olaf; Schultz, Martin G.; Rambadt, Michael; Saini, Rajveer; Hoffmann, Lars; Mallmann, Daniel

2017-04-01

Global model data of atmospheric composition produced by the Copernicus Atmospheric Monitoring Service (CAMS) is collected since 2010 at FZ Jülich and serves as boundary condition for use by Regional Air Quality (RAQ) modellers world-wide. RAQ models need time-resolved meteorological as well as chemical lateral boundary conditions for their individual model domains. While the meteorological data usually come from well-established global forecast systems, the chemical boundary conditions are not always well defined. In the past, many models used 'climatic' boundary conditions for the tracer concentrations, which can lead to significant concentration biases, particularly for tracers with longer lifetimes which can be transported over long distances (e.g. over the whole northern hemisphere) with the mean wind. The Copernicus approach utilizes extensive near-realtime data assimilation of atmospheric composition data observed from space which gives additional reliability to the global modelling data and is well received by the RAQ communities. An existing Web Coverage Service (WCS) for sharing these individually tailored model results is currently being re-engineered to make use of a modern, scalable database technology in order to improve performance, enhance flexibility, and allow the operation of catalogue services. The new Jülich Atmospheric Data Distributions Server (JADDS) adheres to the Web Coverage Service WCS2.0 standard as defined by the Open Geospatial Consortium OGC. This enables the user groups to flexibly define datasets they need by selecting a subset of chemical species or restricting geographical boundaries or the length of the time series. The data is made available in the form of different catalogues stored locally on our server. In addition, the Jülich OWS Interface (JOIN) provides interoperable web services allowing for easy download and visualization of datasets delivered from WCS servers via the internet. We will present the prototype JADDS server and address the major issues identified when relocating large four-dimensional datasets into a RASDAMAN raster array database. So far the RASDAMAN support for data available in netCDF format is limited with respect to metadata related to variables and axes. For community-wide accepted solutions, selected data coverages shall result in downloadable netCDF files including metadata complying with the netCDF CF Metadata Conventions standard (http://cfconventions.org/). This can be achieved by adding custom metadata elements for RASDAMAN bands (model levels) on data ingestion. Furthermore, an optimization strategy for ingestion of several TB of 4D model output data will be outlined.

Ten years of OMI observations: scientific highlights and impacts on the new generation of UV/VIS satellite instrumentation

NASA Astrophysics Data System (ADS)

Levelt, Pieternel; Veefkind, Pepijn; Bhartia, Pawan; Joiner, Joanna; Tamminen, Johanna; OMI Science Team

2014-05-01

On July 15, 2004 Ozone Monitoring Instrument (OMI) was successfully launched from the Vandenberg military air force basis in California, USA, on NASA's EOS-Aura spacecraft. OMI is the first of a new generation of UV/VIS nadir solar backscatter imaging spectrometers, which provides nearly global coverage in one day with an unprecedented spatial resolution of 13 x 24 km2. OMI measures solar irradiance and Earth radiances in the wavelength range of 270 to 500 nm with a spectral resolution of about 0.5 nm. OMI is designed and built by the Netherlands and Finland and is also a third party mission of ESA. The major step that was made in the OMI instrument compared to its predecessors is the use of 2-dimensional detector arrays (CCDs) in a highly innovative small optical design. These innovations enable the combination of a high spatial resolution and a good spectral resolution with daily global coverage. OMI measures a range of trace gases (O3, NO2, SO2, HCHO, BrO, OClO, H2O), clouds and aerosols. Albeit OMI is already 5 years over its design lifetime, the instrument is still fully operational. The successor of OMI is TROPOMI (TROPOspheric Monitoring Instrument) on the Copernicus Sentinel-5 precursor mission, planned for launch in 2015. OMI's unique capabilities rely in measuring tropospheric trace gases with a small footprint and daily global coverage. The unprecedented spatial resolution of the instrument revealed for the first time tropospheric pollution maps on a daily basis with urban scale resolution leading to improved air quality forecasts. The OMI measurements also improve our understanding of air quality and the interaction between air quality and climate change by combining measurements of air pollutants and aerosols. In recent years the data are also used for obtaining high-resolution global emission maps using inverse modelling or related techniques, challenging the bottom-up inventories based emission maps. In addition to scientific research, OMI also contributes to several operational services, including volcanic plume warning systems for aviation, UV forecasts and the air quality forecasts. In this invited talk an overview will be given of unique findings and new scientific results based on OMI data over the last 10 years and which unique OMI instrument features are recurring in the new generation of UV/VIS satellite instrumentation in Europe, USA and Asia.

Reliability of Navigation Service Provided by the Global Positioning System

DOT National Transportation Integrated Search

1985-09-01

The planned NAVSTAR/GPS satellite constellation of 18 satellites plus 3 active will provide excellent coverage over the continental United States (CONUS) if all are operating properly. This report examines the coverage under conditions of one satelli...

Making sense of global warming: Norwegians appropriating knowledge of anthropogenic climate change.

PubMed

Ryghaug, Marianne; Sørensen, Knut Holtan; Naess, Robert

2011-11-01

This paper studies how people reason about and make sense of human-made global warming, based on ten focus group interviews with Norwegian citizens. It shows that the domestication of climate science knowledge was shaped through five sense-making devices: news media coverage of changes in nature, particularly the weather, the coverage of presumed experts' disagreement about global warming, critical attitudes towards media, observations of political inaction, and considerations with respect to everyday life. These sense-making devices allowed for ambiguous outcomes, and the paper argues four main outcomes with respect to the domestication processes: the acceptors, the tempered acceptors, the uncertain and the sceptics.

WindCam and MSPI: two cloud and aerosol instrument concepts derived from Terra/MISR heritage

NASA Astrophysics Data System (ADS)

Diner, David J.; Mischna, Michael; Chipman, Russell A.; Davis, Ab; Cairns, Brian; Davies, Roger; Kahn, Ralph A.; Muller, Jan-Peter; Torres, Omar

2008-08-01

The Multi-angle Imaging SpectroRadiometer (MISR) has been acquiring global cloud and aerosol data from polar orbit since February 2000. MISR acquires moderately high-resolution imagery at nine view angles from nadir to 70.5°, in four visible/near-infrared spectral bands. Stereoscopic parallax, time lapse among the nine views, and the variation of radiance with angle and wavelength enable retrieval of geometric cloud and aerosol plume heights, height-resolved cloud-tracked winds, and aerosol optical depth and particle property information. Two instrument concepts based upon MISR heritage are in development. The Cloud Motion Vector Camera, or WindCam, is a simplified version comprised of a lightweight, compact, wide-angle camera to acquire multiangle stereo imagery at a single visible wavelength. A constellation of three WindCam instruments in polar Earth orbit would obtain height-resolved cloud-motion winds with daily global coverage, making it a low-cost complement to a spaceborne lidar wind measurement system. The Multiangle SpectroPolarimetric Imager (MSPI) is aimed at aerosol and cloud microphysical properties, and is a candidate for the National Research Council Decadal Survey's Aerosol-Cloud-Ecosystem (ACE) mission. MSPI combines the capabilities of MISR with those of other aerosol sensors, extending the spectral coverage to the ultraviolet and shortwave infrared and incorporating high-accuracy polarimetric imaging. Based on requirements for the nonimaging Aerosol Polarimeter Sensor on NASA's Glory mission, a degree of linear polarization uncertainty of 0.5% is specified within a subset of the MSPI bands. We are developing a polarization imaging approach using photoelastic modulators (PEMs) to accomplish this objective.

Application synergies between the NASA Pre- Aerosol Cloud and ocean Ecosystem (PACE) and Hyperspectral Infrared Imager (HyspIRI) missions

NASA Astrophysics Data System (ADS)

Lee, C. M.; Omar, A. H.; Hook, S. J.; Tzortziou, M.; Luvall, J. C.; Turner, W. W.

2016-02-01

Observations from the Pre-Aerosol Cloud and ocean Ecosystem (PACE) and Hyperspectral InfraRed Imager (HyspIRI) satellite missions are highly complementary and have the potential to significantly advance understanding of various science and applications challenges in the ocean sciences and water quality communities. Scheduled for launch in the 2022 timeframe, PACE is designed to make climate-quality global measurements essential for understanding ocean biology, biogeochemistry and ecology, and determining the role of the ocean in global biogeochemical cycling and ocean ecology, and how it affects and is affected by climate change. PACE will provide high signal-to-noise, hyperspectral observations over an extended spectral range (UV to SWIR) and will have global coverage every 1-2 days, at approximately 1 km spatial resolution; furthermore, PACE is currently designed to include a polarimeter, which will vastly improve atmospheric correction algorithms over water bodies. The PACE mission will enable advances in applications across a range of areas, including oceans, climate, water resources, ecological forecasting, disasters, human health and air quality. HyspIRI, with contiguous measurements in VSWIR, and multispectral measurements in TIR, will be able to provide detailed spectral observations and higher spatial resolution (30 to 60-m) over aquatic systems, but at a temporal resolution that is approximately 5-16 days. HyspIRI would enable improved, detailed studies of aquatic ecosystems, including benthic communities, algal blooms, coral reefs, and wetland species distribution as well as studies of water quality indicators or pollutants such as oil spills, suspended sediment, and colored dissolved organic matter. Together, PACE and HyspIRI will be able to address numerous applications and science priorities, including improving and extending climate data records, and studies of inland, coastal and ocean environments.

Reimagining WHO: leadership and action for a new Director-General.

PubMed

Gostin, Lawrence O; Friedman, Eric A

2017-02-18

Three candidates to be the next WHO Director-General remain: Tedros Adhanom Ghebreyesus, David Nabarro, and Sania Nishtar. The World Health Assembly's ultimate choice will lead an organisation facing daunting internal and external challenges, from its own funding shortfalls to antimicrobial resistance and immense health inequities. The new Director-General must transform WHO into a 21st century institution guided by the right to health. Topping the incoming Director-General's agenda will be a host of growing threats-risks to global health security, antimicrobial resistance, non-communicable diseases, and climate change-but also the transformative potential of the Sustainable Development Goals, including their universal health coverage target. Throughout, the next Director-General should emphasise equality, including through national health equity strategies and, more boldly still, advancing the Framework Convention on Global Health. Success in these areas will require a reinvigorated WHO, with sustainable financing, greater multisector engagement, enhanced accountability and transparency, and strengthened normative leadership. WHO must also evolve its governance to become far more welcoming of civil society and communities. To create the foundation for these transformative changes, the Director-General will need to focus first on gaining political support. This entails improving accountability and transparency to gain member state trust, and enabling meaningful civil society participation in WHO's governance and standing up for the right to health to gain civil society support. Ultimately, in the face of a global environment marked by heightened nationalism and xenophobia, member states must empower the next Director-General to enable WHO to be a bulwark for health and human rights, serving as an inspiring contra-example to today's destructive politics, demonstrating that the community of nations are indeed stronger together. Copyright © 2017 Elsevier Ltd. All rights reserved.

Global yellow fever vaccination coverage from 1970 to 2016: an adjusted retrospective analysis.

PubMed

Shearer, Freya M; Moyes, Catherine L; Pigott, David M; Brady, Oliver J; Marinho, Fatima; Deshpande, Aniruddha; Longbottom, Joshua; Browne, Annie J; Kraemer, Moritz U G; O'Reilly, Kathleen M; Hombach, Joachim; Yactayo, Sergio; de Araújo, Valdelaine E M; da Nóbrega, Aglaêr A; Mosser, Jonathan F; Stanaway, Jeffrey D; Lim, Stephen S; Hay, Simon I; Golding, Nick; Reiner, Robert C

2017-11-01

Substantial outbreaks of yellow fever in Angola and Brazil in the past 2 years, combined with global shortages in vaccine stockpiles, highlight a pressing need to assess present control strategies. The aims of this study were to estimate global yellow fever vaccination coverage from 1970 through to 2016 at high spatial resolution and to calculate the number of individuals still requiring vaccination to reach population coverage thresholds for outbreak prevention. For this adjusted retrospective analysis, we compiled data from a range of sources (eg, WHO reports and health-service-provider registeries) reporting on yellow fever vaccination activities between May 1, 1939, and Oct 29, 2016. To account for uncertainty in how vaccine campaigns were targeted, we calculated three population coverage values to encompass alternative scenarios. We combined these data with demographic information and tracked vaccination coverage through time to estimate the proportion of the population who had ever received a yellow fever vaccine for each second level administrative division across countries at risk of yellow fever virus transmission from 1970 to 2016. Overall, substantial increases in vaccine coverage have occurred since 1970, but notable gaps still exist in contemporary coverage within yellow fever risk zones. We estimate that between 393·7 million and 472·9 million people still require vaccination in areas at risk of yellow fever virus transmission to achieve the 80% population coverage threshold recommended by WHO; this represents between 43% and 52% of the population within yellow fever risk zones, compared with between 66% and 76% of the population who would have required vaccination in 1970. Our results highlight important gaps in yellow fever vaccination coverage, can contribute to improved quantification of outbreak risk, and help to guide planning of future vaccination efforts and emergency stockpiling. The Rhodes Trust, Bill & Melinda Gates Foundation, the Wellcome Trust, the National Library of Medicine of the National Institutes of Health, the European Union's Horizon 2020 research and innovation programme. Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. Published by Elsevier Ltd.. All rights reserved.

Mapping of the Moon by Clementine

USGS Publications Warehouse

McEwen, A.S.; Robinson, M.S.

1997-01-01

The "faster, cheaper, better" Clementine spacecraft mission mapped the Moon from February 19 to May 3, 1994. Global coverage was acquired in 11 spectral bandpasses from 415 to 2792 nm and at resolutions of 80-330 m/pixel; a thermal-infrared camera sampled ???20% of the surface; a high-resolution camera sampled selected areas (especially the polar regions); and a lidar altimeter mapped the large-scale topography up to latitudes of ??75??. The spacecraft was in a polar, elliptical orbit, 400-450 km periselene altitude. Periselene latitude was -28.5?? for the first month of mapping, then moved to +28.5??. NASA is supporting the archiving, systematic processing, and analysis of the ???1.8 million lunar images and other datasets. A new global positional network has been constructed from 43,000 images and ???0.5 million match points; new digital maps will facilitate future lunar exploration. In-flight calibrations now enable photometry to a high level of precision for the uv-visible CCD camera. Early science results include: (1) global models of topography, gravity, and crustal thicknesses; (2) new information on the topography and structure of multiring impact basins; (3) evidence suggestive of water ice in large permanent shadows near the south pole; (4) global mapping of iron abundances; and (5) new constraints on the Phanerozoic cratering rate of the Earth. Many additional results are expected following completion of calibration and systematic processing efforts. ?? 1997 COSPAR. Published by Elsevier Science Ltd.

State of equity: childhood immunization in the World Health Organization African Region

PubMed Central

Casey, Rebecca Mary; Hampton, Lee McCalla; Anya, Blanche-philomene Melanga; Gacic-Dobo, Marta; Diallo, Mamadou Saliou; Wallace, Aaron Stuart

2017-01-01

Introduction In 2010, the Global Vaccine Action Plan called on all countries to reach and sustain 90% national coverage and 80% coverage in all districts for the third dose of diphtheria-tetanus-pertussis vaccine (DTP3) by 2015 and for all vaccines in national immunization schedules by 2020. The aims of this study are to analyze recent trends in national vaccination coverage in the World Health Organization African Region andto assess how these trends differ by country income category. Methods We compared national vaccination coverage estimates for DTP3 and the first dose of measles-containing vaccine (MCV) obtained from the World Health Organization (WHO)/United Nations Children’s Fund (UNICEF) joint estimates of national immunization coverage for all African Region countries. Using United Nations (UN) population estimates of surviving infants and country income category for the corresponding year, we calculated population-weighted average vaccination coverage by country income category (i.e., low, lower middle, and upper middle-income) for the years 2000, 2005, 2010 and 2015. Results DTP3 coverage in the African Region increased from 52% in 2000 to 76% in 2015,and MCV1 coverage increased from 53% to 74% during the same period, but with considerable differences among countries. Thirty-six African Region countries were low income in 2000 with an average DTP3 coverage of 50% while 26 were low income in 2015 with an average coverage of 80%. Five countries were lower middle-income in 2000 with an average DTP3 coverage of 84% while 12 were lower middle-income in 2015 with an average coverage of 69%. Five countries were upper middle-income in 2000 with an average DTP3 coverage of 73% and eight were upper middle-income in 2015 with an average coverage of 76%. Conclusion Disparities in vaccination coverage by country persist in the African Region, with countries that were lower middle-income having the lowest coverage on average in 2015. Monitoring and addressing these disparities is essential for meeting global immunization targets. PMID:29296140

Advancements in Open Geospatial Standards for Photogrammetry and Remote Sensing from Ogc

NASA Astrophysics Data System (ADS)

Percivall, George; Simonis, Ingo

2016-06-01

The necessity of open standards for effective sharing and use of remote sensing continues to receive increasing emphasis in policies of agencies and projects around the world. Coordination on the development of open standards for geospatial information is a vital step to insure that the technical standards are ready to support the policy objectives. The mission of the Open Geospatial Consortium (OGC) is to advance development and use of international standards and supporting services that promote geospatial interoperability. To accomplish this mission, OGC serves as the global forum for the collaboration of geospatial data / solution providers and users. Photogrammetry and remote sensing are sources of the largest and most complex geospatial information. Some of the most mature OGC standards for remote sensing include the Sensor Web Enablement (SWE) standards, the Web Coverage Service (WCS) suite of standards, encodings such as NetCDF, GMLJP2 and GeoPackage, and the soon to be approved Discrete Global Grid Systems (DGGS) standard. In collaboration with ISPRS, OGC working with government, research and industrial organizations continue to advance the state of geospatial standards for full use of photogrammetry and remote sensing.

Measuring Carbon Monoxide With TROPOMI: First Results and a Comparison With ECMWF-IFS Analysis Data

NASA Astrophysics Data System (ADS)

Borsdorff, T.; Aan de Brugh, J.; Hu, H.; Aben, I.; Hasekamp, O.; Landgraf, J.

2018-03-01

The Tropospheric Monitoring Instrument (TROPOMI) was launched onboard of the European Space Agency's (ESA) Sentinel-5P satellite. One of the mission's key products is the total column density of carbon monoxide, inferred from TROPOMI's 2.3 μm measurements. Using the operational processing algorithm, we analyze six subsequent days of measurements during the commissioning phase. The TROPOMI product is compared with CO fields from the European Centre for Medium-Range Weather Forecasts (ECMWF) assimilation system. Globally, a small mean difference between the data sets of 3.2 ± 5.5% with a correlation coefficient of 0.97 is found. The daily global coverage of TROPOMI enables it to capture day-to-day evolution of the atmospheric composition. As an example, we discuss the air pollution event of India in November 2017 with high carbon monoxide (CO) concentrations, which partly dispersed when the CO polluted air was transported north alongside the Himalaya to China. The striking agreement and also regional differences with ECMWF indicate new exciting applications for the TROPOMI CO data product.

Optical beamforming based on microwave photonic signal processing

NASA Astrophysics Data System (ADS)

Anzalchi, J.; Perrott, R.; Latunde-Dada, K.; Oldenbeuving, R. M.; Roeloffzen, C. G. H.; Van Dijk, P. W. L.; Hoekman, M.; Leeuwis, H.; Leinse, A.

2017-09-01

Over the past few years considerable attention has been focussed on the inclusion of flexibility in communication satellite payloads. The purpose of this flexibility is to enable a given satellite on command to support different frequency plans, re-configure coverage in response to changing traffic demands and re-configure interconnectivity between coverages.

Validity of vaccination cards and parental recall to estimate vaccination coverage: a systematic review of the literature.

PubMed

Miles, Melody; Ryman, Tove K; Dietz, Vance; Zell, Elizabeth; Luman, Elizabeth T

2013-03-15

Immunization programs frequently rely on household vaccination cards, parental recall, or both to calculate vaccination coverage. This information is used at both the global and national level for planning and allocating performance-based funds. However, the validity of household-derived coverage sources has not yet been widely assessed or discussed. To advance knowledge on the validity of different sources of immunization coverage, we undertook a global review of literature. We assessed concordance, sensitivity, specificity, positive and negative predictive value, and coverage percentage point difference when subtracting household vaccination source from a medical provider source. Median coverage difference per paper ranged from -61 to +1 percentage points between card versus provider sources and -58 to +45 percentage points between recall versus provider source. When card and recall sources were combined, median coverage difference ranged from -40 to +56 percentage points. Overall, concordance, sensitivity, specificity, positive and negative predictive value showed poor agreement, providing evidence that household vaccination information may not be reliable, and should be interpreted with care. While only 5 papers (11%) included in this review were from low-middle income countries, low-middle income countries often rely more heavily on household vaccination information for decision making. Recommended actions include strengthening quality of child-level data and increasing investments to improve vaccination card availability and card marking. There is also an urgent need for additional validation studies of vaccine coverage in low and middle income countries. Copyright © 2013. Published by Elsevier Ltd.

Health Care Coverage Decision Making in Low- and Middle-Income Countries: Experiences from 25 Coverage Schemes.

PubMed

Gutierrez, Hialy; Shewade, Ashwini; Dai, Minghan; Mendoza-Arana, Pedro; Gómez-Dantés, Octavio; Jain, Nishant; Khonelidze, Irma; Nabyonga-Orem, Juliet; Saleh, Karima; Teerawattananon, Yot; Nishtar, Sania; Hornberger, John

2015-08-01

Lessons learned by countries that have successfully implemented coverage schemes for health services may be valuable for other countries, especially low- and middle-income countries (LMICs), which likewise are seeking to provide/expand coverage. The research team surveyed experts in population health management from LMICs for information on characteristics of health care coverage schemes and factors that influenced decision-making processes. The level of coverage provided by the different schemes varied. Nearly all the health care coverage schemes involved various representatives and stakeholders in their decision-making processes. Maternal and child health, cardiovascular diseases, cancer, and HIV were among the highest priorities guiding coverage development decisions. Evidence used to inform coverage decisions included medical literature, regional and global epidemiology, and coverage policies of other coverage schemes. Funding was the most commonly reported reason for restricting coverage. This exploratory study provides an overview of health care coverage schemes from participating LMICs and contributes to the scarce evidence base on coverage decision making. Sharing knowledge and experiences among LMICs can support efforts to establish systems for accessible, affordable, and equitable health care.

Strengthening routine immunization systems to improve global vaccination coverage.

PubMed

Sodha, S V; Dietz, V

2015-03-01

Global coverage with the third dose of diphtheria-tetanus-pertussis vaccine among children under 1 year of age stagnated at ∼ 83-84% during 2008-13. Annual World Health Organization and UNICEF-derived national vaccination coverage estimates. Incomplete vaccination is associated with poor socioeconomic status, lower education, non-use of maternal-child health services, living in conflict-affected areas, missed immunization opportunities and cancelled vaccination sessions. Vaccination platforms must expand to include older ages including the second year of life. Immunization programmes, including eradication and elimination initiatives such as those for polio and measles, must integrate within the broader health system. The Global Vaccine Action Plan (GVAP) 2011-20 is a framework for strengthening immunization systems, emphasizing country ownership, shared responsibility, equity, integration, sustainability and innovation. Immunization programmes should identify, monitor and evaluate gaps and interventions within the GVAP framework. Published by Oxford University Press 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

[Complete immunization coverage and reasons for non-vaccination in a periurban area of Abidjan].

PubMed

Sackou, K J; Oga, A S S; Desquith, A A; Houenou, Y; Kouadio, K L

2012-10-01

An immunization coverage survey was conducted among children aged 12-59 months in a suburban neighbourhood in Abidjan. The objective was to determine the complete immunization coverage, the reasons for non-vaccination and factors influencing the immunization status of children. The method of exhaustive sampling enabled us to interview the mothers of 669 children using a questionnaire. Overall vaccination coverage was 68.6% with 1.2%, with 1.2% of children never having received vaccine. The logistic regression analysis showed that the level of education, knowledge of the immunization schedule and the marital status of mothers, as well as the type of habitat, were associated with full immunization of children. These determinants must be taken into account to improve vaccination coverage.

An analytic algorithm for global coverage of the revisiting orbit and its application to the CFOSAT satellite

NASA Astrophysics Data System (ADS)

Xu, Ming; Huang, Li

2014-08-01

This paper addresses a new analytic algorithm for global coverage of the revisiting orbit and its application to the mission revisiting the Earth within long periods of time, such as Chinese-French Oceanic Satellite (abbr., CFOSAT). In the first, it is presented that the traditional design methodology of the revisiting orbit for some imaging satellites only on the single (ascending or descending) pass, and the repeating orbit is employed to perform the global coverage within short periods of time. However, the selection of the repeating orbit is essentially to yield the suboptimum from the rare measure of rational numbers of passes per day, which will lose lots of available revisiting orbits. Thus, an innovative design scheme is proposed to check both rational and irrational passes per day to acquire the relationship between the coverage percentage and the altitude. To improve the traditional imaging only on the single pass, the proposed algorithm is mapping every pass into its ascending and descending nodes on the specified latitude circle, and then is accumulating the projected width on the circle by the field of view of the satellite. The ergodic geometry of coverage percentage produced from the algorithm is affecting the final scheme, such as the optimal one owning the largest percentage, and the balance one possessing the less gradient in its vicinity, and is guiding to heuristic design for the station-keeping control strategies. The application of CFOSAT validates the feasibility of the algorithm.

Geologic map of Io

USGS Publications Warehouse

Williams, David A.; Keszthelyi, Laszlo P.; Crown, David A.; Yff, Jessica A.; Jaeger, Windy L.; Schenk, Paul M.; Geissler, Paul E.; Becker, Tammy L.

2011-01-01

Io, discovered by Galileo Galilei on January 7–13, 1610, is the innermost of the four Galilean satellites of the planet Jupiter (Galilei, 1610). It is the most volcanically active object in the Solar System, as recognized by observations from six National Aeronautics and Space Administration (NASA) spacecraft: Voyager 1 (March 1979), Voyager 2 (July 1979), Hubble Space Telescope (1990–present), Galileo (1996–2001), Cassini (December 2000), and New Horizons (February 2007). The lack of impact craters on Io in any spacecraft images at any resolution attests to the high resurfacing rate (1 cm/yr) and the dominant role of active volcanism in shaping its surface. High-temperature hot spots detected by the Galileo Solid-State Imager (SSI), Near-Infrared Mapping Spectrometer (NIMS), and Photopolarimeter-Radiometer (PPR) usually correlate with darkest materials on the surface, suggesting active volcanism. The Voyager flybys obtained complete coverage of Io's subjovian hemisphere at 500 m/pixel to 2 km/pixel, and most of the rest of the satellite at 5–20 km/pixel. Repeated Galileo flybys obtained complementary coverage of Io's antijovian hemisphere at 5 m/pixel to 1.4 km/pixel. Thus, the Voyager and Galileo data sets were merged to enable the characterization of the whole surface of the satellite at a consistent resolution. The United States Geological Survey (USGS) produced a set of four global mosaics of Io in visible wavelengths at a spatial resolution of 1 km/pixel, released in February 2006, which we have used as base maps for this new global geologic map. Much has been learned about Io's volcanism, tectonics, degradation, and interior since the Voyager flybys, primarily during and following the Galileo Mission at Jupiter (December 1995–September 2003), and the results have been summarized in books published after the end of the Galileo Mission. Our mapping incorporates this new understanding to assist in map unit definition and to provide a global synthesis of Io's geology.

Measles and Rubella Global Strategic Plan 2012-2020 midterm review.

PubMed

Orenstein, W A; Hinman, A; Nkowane, B; Olive, J M; Reingold, A

2018-01-11

1. Measles eradication is the ultimate goal but it is premature to set a date for its accomplishment. Existing regional elimination goals should be vigorously pursued to enable setting a global target by 2020. 2. The basic strategic approaches articulated in the Global Measles and Rubella Strategic Plan 2012-2020 are valid to achieve the goals but have not been fully implemented (or not appropriately adapted to local situations). 3. The report recommends a shift from primary reliance on supplementary immunization activities (SIAs) to assure two doses of measles-containing vaccine (MCV) are delivered to the target population to primary reliance on ongoing services to assure administration of two doses of MCV. Regular high quality SIAs will still be necessary while ongoing services are being strengthened. 4. The report recommends a shift from primary reliance on coverage to measure progress to incorporating disease incidence as a major indicator. 5. The report recommends that the measles/rubella vaccination program be considered an indicator for the quality of the overall immunization program and that measles/rubella incidence and measles and rubella vaccination coverage be considered as primary indicators of immunization program performance. 6. Polio transition presents both risks and opportunities: risks should be minimized and opportunities maximized. 7. A school entry immunization check could contribute significantly to strengthening overall immunization services with assurance that recommended doses of measles and rubella vaccines as well as other vaccines have been delivered and providing those vaccines at that time if the child is un- or under-vaccinated. 8. Program decisions should increasingly be based on good quality data and appropriate analysis. 9. The incorporation of rubella vaccination into the immunization program needs to be accelerated - it should be accorded equivalent emphasis as measles. 10. Outbreak investigation and response are critical but the most important thing is to prevent outbreaks. Copyright © 2017 World Health Organization. Published by Elsevier Ltd.. All rights reserved.

Enhancing Political Will for Universal Health Coverage in Nigeria.

PubMed

Aregbeshola, Bolaji S

2017-01-01

Universal health coverage aims to increase equity in access to quality health care services and to reduce financial risk due to health care costs. It is a key component of international health agenda and has been a subject of worldwide debate. Despite differing views on its scope and pathways to reach it, there is a global consensus that all countries should work toward universal health coverage. The goal remains distant for many African countries, including Nigeria. This is mostly due to lack of political will and commitment among political actors and policymakers. Evidence from countries such as Ghana, Chile, Mexico, China, Thailand, Turkey, Rwanda, Vietnam and Indonesia, which have introduced at least some form of universal health coverage scheme, shows that political will and commitment are key to the adoption of new laws and regulations for reforming coverage. For Nigeria to improve people's health, reduce poverty and achieve prosperity, universal health coverage must be vigorously pursued at all levels. Political will and commitment to these goals must be expressed in legal mandates and be translated into policies that ensure increased public health care financing for the benefit of all Nigerians. Nigeria, as part of a global system, cannot afford to lag behind in striving for this overarching health goal.

On the demands on imaging spectrometry for the monitoring of global vegetation fluorescence from space

NASA Astrophysics Data System (ADS)

Kraft, S.; Del Bello, U.; Drusch, M.; Gabriele, A.; Harnisch, B.; Moreno, J.

2013-09-01

Vegetation fluorescence when measured from space contributes only a tiny fraction of the signal coming on top of the reflected radiance by the Earth surface and the atmosphere. As a consequence, imaging spectrometers have to provide sufficient throughput and radiometric accuracy to enable accurate global monitoring of the daily to seasonal variations of the Earth's vegetation breath, which is particularly challenging if ground resolutions of a few hundred meters are targeted. Since fluorescence retrieval algorithms have to make corrections for atmospheric effects, it is necessary to provide sufficient spectral resolution, so that signal alterations due to the main parameters such as surface pressure, atmospheric temperature profile, vertical distribution of aerosols concentration, and water vapour content can be accurately modelled. ESA's Earth Explorer 8 candidate mission FLEX carries a Fluorescence Imaging Spectrometer (FLORIS), which has been designed and optimised to enable such measurement. The spectrometer will measure in a spectral range between 500 and 780 nm and provide high spectral resolution of 0.3 nm in particular at the Oxygen-A and -B bands. It will also cover the photochemical reflection features between 500 and 600 nm, the Chlorophyll absorption region between 600 and 677 nm, and the red-edge in the region of 697 to 755 nm. FLEX will fly in formation with Sentinel-3 in order to further enhance the spectral coverage from measurements made by the Sentinel-3 instruments OLCI and SLSTR, particularly for cloud screening and proper characterization of the atmospheric status.

Development of multi-sensor global cloud and radiance composites for earth radiation budget monitoring from DSCOVR

NASA Astrophysics Data System (ADS)

Khlopenkov, Konstantin; Duda, David; Thieman, Mandana; Minnis, Patrick; Su, Wenying; Bedka, Kristopher

2017-10-01

The Deep Space Climate Observatory (DSCOVR) enables analysis of the daytime Earth radiation budget via the onboard Earth Polychromatic Imaging Camera (EPIC) and National Institute of Standards and Technology Advanced Radiometer (NISTAR). Radiance observations and cloud property retrievals from low earth orbit and geostationary satellite imagers have to be co-located with EPIC pixels to provide scene identification in order to select anisotropic directional models needed to calculate shortwave and longwave fluxes. A new algorithm is proposed for optimal merging of selected radiances and cloud properties derived from multiple satellite imagers to obtain seamless global hourly composites at 5-km resolution. An aggregated rating is employed to incorporate several factors and to select the best observation at the time nearest to the EPIC measurement. Spatial accuracy is improved using inverse mapping with gradient search during reprojection and bicubic interpolation for pixel resampling. The composite data are subsequently remapped into EPIC-view domain by convolving composite pixels with the EPIC point spread function defined with a half-pixel accuracy. PSF-weighted average radiances and cloud properties are computed separately for each cloud phase. The algorithm has demonstrated contiguous global coverage for any requested time of day with a temporal lag of under 2 hours in over 95% of the globe.

Development of Multi-Sensor Global Cloud and Radiance Composites for Earth Radiation Budget Monitoring from DSCOVR

NASA Technical Reports Server (NTRS)

Khlopenkov, Konstantin; Duda, David; Thieman, Mandana; Minnis, Patrick; Su, Wenying; Bedka, Kristopher

2017-01-01

The Deep Space Climate Observatory (DSCOVR) enables analysis of the daytime Earth radiation budget via the onboard Earth Polychromatic Imaging Camera (EPIC) and National Institute of Standards and Technology Advanced Radiometer (NISTAR). Radiance observations and cloud property retrievals from low earth orbit and geostationary satellite imagers have to be co-located with EPIC pixels to provide scene identification in order to select anisotropic directional models needed to calculate shortwave and longwave fluxes. A new algorithm is proposed for optimal merging of selected radiances and cloud properties derived from multiple satellite imagers to obtain seamless global hourly composites at 5-kilometer resolution. An aggregated rating is employed to incorporate several factors and to select the best observation at the time nearest to the EPIC measurement. Spatial accuracy is improved using inverse mapping with gradient search during reprojection and bicubic interpolation for pixel resampling. The composite data are subsequently remapped into EPIC-view domain by convolving composite pixels with the EPIC point spread function (PSF) defined with a half-pixel accuracy. PSF-weighted average radiances and cloud properties are computed separately for each cloud phase. The algorithm has demonstrated contiguous global coverage for any requested time of day with a temporal lag of under 2 hours in over 95 percent of the globe.

Measuring Progress Toward Universal Health Coverage: Does the Monitoring Framework of Bangladesh Need Further Improvement?

PubMed

Gupta, Rajat Das; Shahabuddin, Asm

2018-01-08

This review aimed to compare Bangladesh's Universal Health Coverage (UHC) monitoring framework with the global-level recommendations and to find out the existing gaps of Bangladesh's UHC monitoring framework compared to the global recommendations. In order to reach the aims of the review, we systematically searched two electronic databases - PubMed and Google Scholar - by using appropriate keywords to select articles that describe issues related to UHC and the monitoring framework of UHC applied globally and particularly in Bangladesh. Four relevant documents were found and synthesized. The review found that Bangladesh incorporated all of the recommendations suggested by the global monitoring framework regarding mentoring the financial risk protection and equity perspective. However, a significant gap in the monitoring framework related to service coverage was observed. Although Bangladesh has a significant burden of mental illnesses, cataract, and neglected tropical diseases, indicators related to these issues were absent in Bangladesh's UHC framework. Moreover, palliative-care-related indicators were completely missing in the framework. The results of this review suggest that Bangladesh should incorporate these indicators in their UHC monitoring framework in order to track the progress of the country toward UHC more efficiently and in a robust way.

Global Seismic Imaging Based on Adjoint Tomography

NASA Astrophysics Data System (ADS)

Bozdag, E.; Lefebvre, M.; Lei, W.; Peter, D. B.; Smith, J. A.; Zhu, H.; Komatitsch, D.; Tromp, J.

2013-12-01

Our aim is to perform adjoint tomography at the scale of globe to image the entire planet. We have started elastic inversions with a global data set of 253 CMT earthquakes with moment magnitudes in the range 5.8 ≤ Mw ≤ 7 and used GSN stations as well as some local networks such as USArray, European stations, etc. Using an iterative pre-conditioned conjugate gradient scheme, we initially set the aim to obtain a global crustal and mantle model with confined transverse isotropy in the upper mantle. Global adjoint tomography has so far remained a challenge mainly due to computational limitations. Recent improvements in our 3D solvers (e.g., a GPU version) and access to high-performance computational centers (e.g., ORNL's Cray XK7 "Titan" system) now enable us to perform iterations with higher-resolution (T > 9 s) and longer-duration (200 min) simulations to accommodate high-frequency body waves and major-arc surface waves, respectively, which help improve data coverage. The remaining challenge is the heavy I/O traffic caused by the numerous files generated during the forward/adjoint simulations and the pre- and post-processing stages of our workflow. We improve the global adjoint tomography workflow by adopting the ADIOS file format for our seismic data as well as models, kernels, etc., to improve efficiency on high-performance clusters. Our ultimate aim is to use data from all available networks and earthquakes within the magnitude range of our interest (5.5 ≤ Mw ≤ 7) which requires a solid framework to manage big data in our global adjoint tomography workflow. We discuss the current status and future of global adjoint tomography based on our initial results as well as practical issues such as handling big data in inversions and on high-performance computing systems.

Constellation analysis of an integrated AIS/remote sensing spaceborne system for ship detection

NASA Astrophysics Data System (ADS)

Graziano, Maria Daniela; D'Errico, Marco; Razzano, Elena

2012-08-01

A future system integrating data from remote sensing and upcoming AIS satellites is analyzed through the development of a novel design method for global, discontinuous coverage constellations. It is shown that 8 AIS satellites suffice to guarantee global coverage and a ship location update of 50 min if the spaceborne AIS receiver has a swath of 2800 nm. Furthermore, synergic utilization of COSMO/SkyMed and Radarsat-C data would provide a mean revisit time of 7 h, with AIS information available within 25 min from SAR data acquisition.

Ghana's National Health insurance scheme and maternal and child health: a mixed methods study.

PubMed

Singh, Kavita; Osei-Akoto, Isaac; Otchere, Frank; Sodzi-Tettey, Sodzi; Barrington, Clare; Huang, Carolyn; Fordham, Corinne; Speizer, Ilene

2015-03-17

Ghana is attracting global attention for efforts to provide health insurance to all citizens through the National Health Insurance Scheme (NHIS). With the program's strong emphasis on maternal and child health, an expectation of the program is that members will have increased use of relevant services. This paper uses qualitative and quantitative data from a baseline assessment for the Maternal and Newborn errals Evaluation from the Northern and Central Regions to describe women's experiences with the NHIS and to study associations between insurance and skilled facility delivery, antenatal care and early care-seeking for sick children. The assessment included a quantitative household survey (n = 1267 women), a quantitative community leader survey (n = 62), qualitative birth narratives with mothers (n = 20) and fathers (n = 18), key informant interviews with health care workers (n = 5) and focus groups (n = 3) with community leaders and stakeholders. The key independent variables for the quantitative analyses were health insurance coverage during the past three years (categorized as all three years, 1-2 years or no coverage) and health insurance during the exact time of pregnancy. Quantitative findings indicate that insurance coverage during the past three years and insurance during pregnancy were associated with greater use of facility delivery but not ANC. Respondents with insurance were also significantly more likely to indicate that an illness need not be severe for them to take a sick child for care. The NHIS does appear to enable pregnant women to access services and allow caregivers to seek care early for sick children, but both the quantitative and qualitative assessments also indicated that the poor and least educated were less likely to have insurance than their wealthier and more educated counterparts. Findings from the qualitative interviews uncovered specific challenges women faced regarding registration for the NHIS and other barriers such lack of understanding of who and what services were covered for free. Efforts should be undertaken so all individuals understand the NHIS policy including who is eligible for free services and what services are covered. Increasing access to health insurance will enable Ghana to further improve maternal and child health outcomes.

Constellations of elliptical inclined lunar orbits providing polar and global coverage

NASA Technical Reports Server (NTRS)

Ely, Todd A.; Lieb, Erica

2005-01-01

Prior results have developed a methodology for selecting a long-lived constellation of 3 satellites that provide persistent, stable coverage to either the North or South Pole with no requirement for stationkeeping under the influence of only gravitational perturbations. In the present study, the sensitivity of this coverage in the presence of non-gravitational forces is determined, and a design strategy is formulated that minimizes any potential sensitivity to these accelerations.

Public health surveillance and infectious disease detection.

PubMed

Morse, Stephen S

2012-03-01

Emerging infectious diseases, such as HIV/AIDS, SARS, and pandemic influenza, and the anthrax attacks of 2001, have demonstrated that we remain vulnerable to health threats caused by infectious diseases. The importance of strengthening global public health surveillance to provide early warning has been the primary recommendation of expert groups for at least the past 2 decades. However, despite improvements in the past decade, public health surveillance capabilities remain limited and fragmented, with uneven global coverage. Recent initiatives provide hope of addressing this issue, and new technological and conceptual advances could, for the first time, place capability for global surveillance within reach. Such advances include the revised International Health Regulations (IHR 2005) and the use of new data sources and methods to improve global coverage, sensitivity, and timeliness, which show promise for providing capabilities to extend and complement the existing infrastructure. One example is syndromic surveillance, using nontraditional and often automated data sources. Over the past 20 years, other initiatives, including ProMED-mail, GPHIN, and HealthMap, have demonstrated new mechanisms for acquiring surveillance data. In 2009 the U.S. Agency for International Development (USAID) began the Emerging Pandemic Threats (EPT) program, which includes the PREDICT project, to build global capacity for surveillance of novel infections that have pandemic potential (originating in wildlife and at the animal-human interface) and to develop a framework for risk assessment. Improved understanding of factors driving infectious disease emergence and new technological capabilities in modeling, diagnostics and pathogen identification, and communications, such as using the increasing global coverage of cellphones for public health surveillance, can further enhance global surveillance.

The 5As: A practical taxonomy for the determinants of vaccine uptake.

PubMed

Thomson, Angus; Robinson, Karis; Vallée-Tourangeau, Gaëlle

2016-02-17

Suboptimal vaccine uptake in both childhood and adult immunisation programs limits their full potential impact on global health. A recent progress review of the Global Vaccine Action Plan stated that "countries should urgently identify barriers and bottlenecks and implement targeted approaches to increase and sustain coverage". However, vaccination coverage may be determined by a complex mix of demographic, structural, social and behavioral factors. To develop a practical taxonomy to organise the myriad possible root causes of a gap in vaccination coverage rates, we performed a narrative review of the literature and tested whether all non-socio-demographic determinants of coverage could be organised into 4 dimensions: Access, Affordability, Awareness and Acceptance. Forty-three studies were reviewed, from which we identified 23 primary determinants of vaccination uptake. We identified a fifth domain, Activation, which captured interventions such as SMS reminders which effectively nudge people towards getting vaccinated. The 5As taxonomy captured all identified determinants of vaccine uptake. This intuitive taxonomy has already facilitated mutual understanding of the primary determinants of suboptimal coverage within inter-sectorial working groups, a first step towards them developing targeted and effective solutions. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

Towards a Framework for Generating Tests to Satisfy Complex Code Coverage in Java Pathfinder

NASA Technical Reports Server (NTRS)

Staats, Matt

2009-01-01

We present work on a prototype tool based on the JavaPathfinder (JPF) model checker for automatically generating tests satisfying the MC/DC code coverage criterion. Using the Eclipse IDE, developers and testers can quickly instrument Java source code with JPF annotations covering all MC/DC coverage obligations, and JPF can then be used to automatically generate tests that satisfy these obligations. The prototype extension to JPF enables various tasks useful in automatic test generation to be performed, such as test suite reduction and execution of generated tests.

Assessing Coverage of Population-Based and Targeted Fortification Programs with the Use of the Fortification Assessment Coverage Toolkit (FACT): Background, Toolkit Development, and Supplement Overview.

PubMed

Friesen, Valerie M; Aaron, Grant J; Myatt, Mark; Neufeld, Lynnette M

2017-05-01

Food fortification is a widely used approach to increase micronutrient intake in the diet. High coverage is essential for achieving impact. Data on coverage is limited in many countries, and tools to assess coverage of fortification programs have not been standardized. In 2013, the Global Alliance for Improved Nutrition developed the Fortification Assessment Coverage Toolkit (FACT) to carry out coverage assessments in both population-based (i.e., staple foods and/or condiments) and targeted (e.g., infant and young child) fortification programs. The toolkit was designed to generate evidence on program coverage and the use of fortified foods to provide timely and programmatically relevant information for decision making. This supplement presents results from FACT surveys that assessed the coverage of population-based and targeted food fortification programs across 14 countries. It then discusses the policy and program implications of the findings for the potential for impact and program improvement.

Overview of the Martian nightside suprathermal electron depletions

NASA Astrophysics Data System (ADS)

Steckiewicz, Morgane; Garnier, Philippe; André, Nicolas; Mitchell, David; Andersson, Laila; Penou, Emmanuel; Beth, Arnaud; Fedorov, Andrei; Sauvaud, Jean-André; Mazelle, Christian; Lillis, Robert; Brain, David; Espley, Jared; McFadden, James; Halekas, Jasper; Luhmann, Janet; Soobiah, Yasir; Jakosky, Bruce

2017-04-01

Nightside suprathermal electron depletions have been observed at Mars by three spacecraft to date: Mars Global Surveyor (MGS), Mars EXpress (MEX) and the Mars Atmosphere and Volatile EvolutioN (MAVEN) mission. The global coverage of Mars by MEX and MGS at high altitudes (above approximately 250 km) revealed that these structures were mostly observed above strong crustal magnetic field sources which exclude the electrons coming from the dayside or from the tail. The MAVEN orbit now offers the possibility to observe this phenomenon at low altitudes, down to 125 km. A transition region near 170 km has been detected separating the collisional region where electron depletions are mainly due to electron absorption by atmospheric CO2 and the collisionless region where they are mainly due to closed crustal magnetic field loops. MAVEN is now in its third year of data recording and has covered a large range of latitudes, local times and solar zenith angles at low altitudes (<900km) in the nightside. These observations enable us to estimate where the EUV terminator is located, based on the observation that no electron depletions are expected above its location. Through this study the location of the EUV terminator appears to be raised on average by 125 km above the location of the geometrical terminator. However, this location is likely to be different between the dawn and dusk terminator and to vary throughout the different Martian seasons. This coverage has also allowed the observation of regions with recurrent absence of electron depletions even below the transition region near 170 km altitude. These 'no-depletion' areas are localized above the least magnetized area of Mars both in the Northern and Southern hemispheres. A modification in the CO2 density, gravity waves, or the presence of current sheets are potential drivers for that phenomenon.

Determination of Interannual to Decadal Changes in Ice Sheet Mass Balance from Satellite Altimetry

NASA Technical Reports Server (NTRS)

Zwally, H. Jay; Busalacchi, Antonioa J. (Technical Monitor)

2001-01-01

A major uncertainty in predicting sea level rise is the sensitivity of ice sheet mass balance to climate change, as well as the uncertainty in present mass balance. Since the annual water exchange is about 8 mm of global sea level equivalent, the +/- 25% uncertainty in current mass balance corresponds to +/- 2 mm/yr in sea level change. Furthermore, estimates of the sensitivity of the mass balance to temperature change range from perhaps as much as - 10% to + 10% per K. Although the overall ice mass balance and seasonal and inter-annual variations can be derived from time-series of ice surface elevations from satellite altimetry, satellite radar altimeters have been limited in spatial coverage and elevation accuracy. Nevertheless, new data analysis shows mixed patterns of ice elevation increases and decreases that are significant in terms of regional-scale mass balances. In addition, observed seasonal and interannual variations in elevation demonstrate the potential for relating the variability in mass balance to changes in precipitation, temperature, and melting. From 2001, NASA's ICESat laser altimeter mission will provide significantly better elevation accuracy and spatial coverage to 86 deg latitude and to the margins of the ice sheets. During 3 to 5 years of ICESat-1 operation, an estimate of the overall ice sheet mass balance and sea level contribution will be obtained. The importance of continued ice monitoring after the first ICESat is illustrated by the variability in the area of Greenland surface melt observed over 17-years and its correlation with temperature. In addition, measurement of ice sheet changes, along with measurements of sea level change by a series of ocean altimeters, should enable direct detection of ice level and global sea level correlations.

Regional to Global Biogenic Isoprene Emission Responses to Changes in Vegetation From 2000 to 2015

NASA Astrophysics Data System (ADS)

Chen, W. H.; Guenther, A. B.; Wang, X. M.; Chen, Y. H.; Gu, D. S.; Chang, M.; Zhou, S. Z.; Wu, L. L.; Zhang, Y. Q.

2018-04-01

Isoprene, a dominant biogenic volatile organic compound that is mainly emitted by trees, has a significant impact on the atmospheric chemistry. Regional to global changes in biogenic isoprene emission associated with vegetation variations between 2000 and 2015 were estimated using the MEGAN model with satellite land cover data for inputs in this study. The satellite data estimates of land cover changes were compared to results from previous investigators that have either conducted regional studies or have used lower resolution land cover data. The analysis indicates that tree coverage increases of >5% occurred in 13% of locations including in central China and Europe. In contrast, a decrease of >5% was observed in about 5% of locations, especially in tropical regions. The trends in global tree coverage from 2000 to 2015 resulted in a global isoprene emission decrease of only 1.5%, but there were significant regional variations. Obvious decreases in tree coverage in some tropical areas (e.g., Amazon Basin, Western Africa, Southeast Asia) resulted in a 10% reduction of regional isoprene emission due to agricultural expansion. Distinct increments of isoprene emission (5-10%) were mainly found in Northeast China and India and were associated with afforestation efforts. Deforestation and afforestation associated with managed plantations does not only affect the total forest coverage but also impacts average isoprene emission capacity, which can result in accelerated isoprene emission variations. Consequently, isoprene variation assessments are needed that not only account for changes in vegetation fractions but also consider the changes in plant species compositions of forests and other landscapes.

Universal Health Coverage - The Critical Importance of Global Solidarity and Good Governance Comment on "Ethical Perspective: Five Unacceptable Trade-offs on the Path to Universal Health Coverage".

PubMed

Reis, Andreas A

2016-06-07

This article provides a commentary to Ole Norheim' s editorial entitled "Ethical perspective: Five unacceptable trade-offs on the path to universal health coverage." It reinforces its message that an inclusive, participatory process is essential for ethical decision-making and underlines the crucial importance of good governance in setting fair priorities in healthcare. Solidarity on both national and international levels is needed to make progress towards the goal of universal health coverage (UHC). © 2016 by Kerman University of Medical Sciences.

A Constellation of CubeSat InSAR Sensors for Rapid-Revisit Surface Deformation Studies

NASA Astrophysics Data System (ADS)

Wye, L.; Lee, S.; Yun, S. H.; Zebker, H. A.; Stock, J. D.; Wicks, C. W., Jr.; Doe, R.

2016-12-01

The 2007 NRC Decadal Survey for Earth Sciences highlights three major Earth surface deformation themes: 1) solid-earth hazards and dynamics; 2) human health and security; and 3) land-use change, ecosystem dynamics and biodiversity. Space-based interferometric synthetic aperture radar (InSAR) is a key change detection tool for addressing these themes. Here, we describe the mission and radar payload design for a constellation of S-band InSAR sensors specifically designed to provide the global, high temporal resolution, sub-cm level deformation accuracy needed to address some of the major Earth system goals. InSAR observations with high temporal resolution are needed to properly monitor certain nonlinearly time-varying features (e.g., unstable volcanoes, active fault lines, and heavily-used groundwater or hydrocarbon reservoirs). Good temporal coverage is also needed to reduce atmospheric artifacts by allowing multiple acquisitions to be averaged together, since each individual SAR measurement is corrupted by up to several cm of atmospheric noise. A single InSAR platform is limited in how often it can observe a given scene without sacrificing global spatial coverage. Multiple InSAR platforms provide the spatial-temporal flexibility required to maximize the science return. However, building and launching multiple InSAR platforms is cost-prohibitive for traditional satellites. SRI International (SRI) and our collaborators are working to exploit developments in nanosatellite technology, in particular the emergence of the CubeSat standard, to provide high-cadence InSAR capabilities in an affordable package. The CubeSat Imaging Radar for Earth Science (CIRES) subsystem, a prototype SAR elec­tronics package developed by SRI with support from a 2014 NASA ESTO ACT award, is specifically scaled to be a drop-in radar solution for resource-limited delivery systems like CubeSats and small airborne vehicles. Here, we present our mission concept and flow-down requirements for a constellation of 6U InSAR sensors that individually approach the performance capabilities of existing instruments, but collectively surpass the temporal coverage capabilities of single-platform sensors. We discuss the key applications addressed by this constellation and the capabilities that the constellation enables.

Greedy Sparse Approaches for Homological Coverage in Location Unaware Sensor Networks

DTIC Science & Technology

2017-12-08

GlobalSIP); 2013 Dec; Austin , TX . p. 595– 598. 33. Farah C, Schwaner F, Abedi A, Worboys M. Distributed homology algorithm to detect topological events...ARL-TR-8235•DEC 2017 US Army Research Laboratory Greedy Sparse Approaches for Homological Coverage in Location-Unaware Sensor Net- works by Terrence...8235•DEC 2017 US Army Research Laboratory Greedy Sparse Approaches for Homological Coverage in Location-Unaware Sensor Net- works by Terrence J Moore

Seeking consensus on universal health coverage indicators in the sustainable development goals.

PubMed

Reddock, Jennifer

2017-01-01

There is optimism that the inclusion of universal health coverage in the Sustainable Development Goals advances its prominence in global and national health policy. However, formulating indicators for Target 3.8 through the Inter-Agency Expert Group on Sustainable Development Indicators has been challenging. Achieving consensus on the conceptual and methodological aspects of universal health coverage is likely to take some time in multi-stakeholder fora compared with national efforts to select indicators.

Multiscale Drivers of Global Environmental Health

NASA Astrophysics Data System (ADS)

Desai, Manish Anil

In this dissertation, I motivate, develop, and demonstrate three such approaches for investigating multiscale drivers of global environmental health: (1) a metric for analyzing contributions and responses to climate change from global to sectoral scales, (2) a framework for unraveling the influence of environmental change on infectious diseases at regional to local scales, and (3) a model for informing the design and evaluation of clean cooking interventions at community to household scales. The full utility of climate debt as an analytical perspective will remain untapped without tools that can be manipulated by a wide range of analysts, including global environmental health researchers. Chapter 2 explains how international natural debt (IND) apportions global radiative forcing from fossil fuel carbon dioxide and methane, the two most significant climate altering pollutants, to individual entities -- primarily countries but also subnational states and economic sectors, with even finer scales possible -- as a function of unique trajectories of historical emissions, taking into account the quite different radiative efficiencies and atmospheric lifetimes of each pollutant. Owing to its straightforward and transparent derivation, IND can readily operationalize climate debt to consider issues of equity and efficiency and drive scenario exercises that explore the response to climate change at multiple scales. Collectively, the analyses presented in this chapter demonstrate how IND can inform a range of key question on climate change mitigation at multiple scales, compelling environmental health towards an appraisal of the causes and not just the consequences of climate change. The environmental change and infectious disease (EnvID) conceptual framework of Chapter 3 builds on a rich history of prior efforts in epidemiologic theory, environmental science, and mathematical modeling by: (1) articulating a flexible and logical system specification; (2) incorporating transmission groupings linked to public health intervention strategies; (3) emphasizing the intersection of proximal environmental characteristics and transmission cycles; (4) incorporating a matrix formulation to identify knowledge gaps and facilitate an integration of research; and (5) highlighting hypothesis generation amidst dynamic processes. A systems based approach leverages the reality that studies relevant to environmental change and infectious disease are embedded within a wider web of interactions. As scientific understanding advances, the EnvID framework can help integrate the various factors at play in determining environment-disease relationships and the connections between intrinsically multiscale causal networks. In Chapter 4, the coverage effect model functions primarily as a "proof of concept" analysis to address whether the efficacy of a clean cooking technology may be determined by the extent of not only household level use but also community level coverage. Such coverage dependent efficacy, or a "coverage effect," would transform how interventions are studied and deployed. Ensemble results are consistent with the concept that an appreciable coverage effect from clean cooking interventions can manifest within moderately dense communities. Benefits for users derive largely from direct effects; initially, at low coverage levels, almost exclusively so. Yet, as coverage expands within a user's community, a coverage effect becomes increasingly beneficial. In contrast, non users, despite also experiencing comparable exposure reductions from community-level intervention use, cannot proportionately benefit because their exposures remain overwhelmingly dominated by household-level use of traditional solid fuel cookstoves. The coverage effect model strengthens the rationale for public health programs and policies to encourage clean cooking technologies with an added incentive to realize high coverage within contiguous areas. The implications of the modeling exercise extend to priorities for data collection, underscoring the importance of outdoor pollution concentrations during, as well as before and/or after, community cooking windows and also routine measurement of ventilation, meteorology, time activity patterns, and cooking practices. The possibility of a coverage effect necessitates appropriate strategies to estimate not only direct effects but also coverage and total effects to avoid impaired conclusions. The specter of accelerating social and ecological change challenges efforts to respond to climate change, re/emerging infectious diseases, and household air pollution. Environmental health possesses a well-established and well-tested repertoire of methods but contending with multiscale drivers of risk requires complementary approaches, as well. Integrating metrics, frameworks, and models -- and their insights -- into its analytical arsenal can help global environmental health meet the challenges of today and tomorrow. (Abstract shortened by ProQuest.).

Forecasted trends in vaccination coverage and correlations with socioeconomic factors: a global time-series analysis over 30 years.

PubMed

de Figueiredo, Alexandre; Johnston, Iain G; Smith, David M D; Agarwal, Sumeet; Larson, Heidi J; Jones, Nick S

2016-10-01

Incomplete immunisation coverage causes preventable illness and death in both developing and developed countries. Identification of factors that might modulate coverage could inform effective immunisation programmes and policies. We constructed a performance indicator that could quantitatively approximate measures of the susceptibility of immunisation programmes to coverage losses, with an aim to identify correlations between trends in vaccine coverage and socioeconomic factors. We undertook a data-driven time-series analysis to examine trends in coverage of diphtheria, tetanus, and pertussis (DTP) vaccination across 190 countries over the past 30 years. We grouped countries into six world regions according to WHO classifications. We used Gaussian process regression to forecast future coverage rates and provide a vaccine performance index: a summary measure of the strength of immunisation coverage in a country. Overall vaccine coverage increased in all six world regions between 1980 and 2010, with variation in volatility and trends. Our vaccine performance index identified that 53 countries had more than a 50% chance of missing the Global Vaccine Action Plan (GVAP) target of 90% worldwide coverage with three doses of DTP (DTP3) by 2015. These countries were mostly in sub-Saharan Africa and south Asia, but Austria and Ukraine also featured. Factors associated with DTP3 immunisation coverage varied by world region: personal income (Spearman's ρ=0·66, p=0·0011) and government health spending (0·66, p<0·0001) were informative of immunisation coverage in the Eastern Mediterranean between 1980 and 2010, whereas primary school completion was informative of coverage in Africa (0·56, p<0·0001) over the same period. The proportion of births attended by skilled health staff correlated significantly with immunisation coverage across many world regions. Our vaccine performance index highlighted countries at risk of failing to achieve the GVAP target of 90% coverage by 2015, and could aid policy makers' assessments of the strength and resilience of immunisation programmes. Weakening correlations with socioeconomic factors show a need to tackle vaccine confidence, whereas strengthening correlations point to clear factors to address. UK Engineering and Physical Sciences Research Council. Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license. Published by Elsevier Ltd.. All rights reserved.

Validation of NH3 satellite observations by ground-based FTIR measurements

NASA Astrophysics Data System (ADS)

Dammers, Enrico; Palm, Mathias; Van Damme, Martin; Shephard, Mark; Cady-Pereira, Karen; Capps, Shannon; Clarisse, Lieven; Coheur, Pierre; Erisman, Jan Willem

2016-04-01

Global emissions of reactive nitrogen have been increasing to an unprecedented level due to human activities and are estimated to be a factor four larger than pre-industrial levels. Concentration levels of NOx are declining, but ammonia (NH3) levels are increasing around the globe. While NH3 at its current concentrations poses significant threats to the environment and human health, relatively little is known about the total budget and global distribution. Surface observations are sparse and mainly available for north-western Europe, the United States and China and are limited by the high costs and poor temporal and spatial resolution. Since the lifetime of atmospheric NH3 is short, on the order of hours to a few days, due to efficient deposition and fast conversion to particulate matter, the existing surface measurements are not sufficient to estimate global concentrations. Advanced space-based IR-sounders such as the Tropospheric Emission Spectrometer (TES), the Infrared Atmospheric Sounding Interferometer (IASI), and the Cross-track Infrared Sounder (CrIS) enable global observations of atmospheric NH3 that help overcome some of the limitations of surface observations. However, the satellite NH3 retrievals are complex requiring extensive validation. Presently there have only been a few dedicated satellite NH3 validation campaigns performed with limited spatial, vertical or temporal coverage. Recently a retrieval methodology was developed for ground-based Fourier Transform Infrared Spectroscopy (FTIR) instruments to obtain vertical concentration profiles of NH3. Here we show the applicability of retrieved columns from nine globally distributed stations with a range of NH3 pollution levels to validate satellite NH3 products.

Measuring Progress Toward Universal Health Coverage: Does the Monitoring Framework of Bangladesh Need Further Improvement?

PubMed Central

Shahabuddin, ASM

2018-01-01

This review aimed to compare Bangladesh’s Universal Health Coverage (UHC) monitoring framework with the global-level recommendations and to find out the existing gaps of Bangladesh’s UHC monitoring framework compared to the global recommendations. In order to reach the aims of the review, we systematically searched two electronic databases - PubMed and Google Scholar - by using appropriate keywords to select articles that describe issues related to UHC and the monitoring framework of UHC applied globally and particularly in Bangladesh. Four relevant documents were found and synthesized. The review found that Bangladesh incorporated all of the recommendations suggested by the global monitoring framework regarding mentoring the financial risk protection and equity perspective. However, a significant gap in the monitoring framework related to service coverage was observed. Although Bangladesh has a significant burden of mental illnesses, cataract, and neglected tropical diseases, indicators related to these issues were absent in Bangladesh’s UHC framework. Moreover, palliative-care-related indicators were completely missing in the framework. The results of this review suggest that Bangladesh should incorporate these indicators in their UHC monitoring framework in order to track the progress of the country toward UHC more efficiently and in a robust way. PMID:29541562

Estimating Morning Change in Land Surface Temperature from MODIS Day/Night Observations: Applications for Surface Energy Balance Modeling.

PubMed

Hain, Christopher R; Anderson, Martha C

2017-10-16

Observations of land surface temperature (LST) are crucial for the monitoring of surface energy fluxes from satellite. Methods that require high temporal resolution LST observations (e.g., from geostationary orbit) can be difficult to apply globally because several geostationary sensors are required to attain near-global coverage (60°N to 60°S). While these LST observations are available from polar-orbiting sensors, providing global coverage at higher spatial resolutions, the temporal sampling (twice daily observations) can pose significant limitations. For example, the Atmosphere Land Exchange Inverse (ALEXI) surface energy balance model, used for monitoring evapotranspiration and drought, requires an observation of the morning change in LST - a quantity not directly observable from polar-orbiting sensors. Therefore, we have developed and evaluated a data-mining approach to estimate the mid-morning rise in LST from a single sensor (2 observations per day) of LST from the Moderate Resolution Imaging Spectroradiometer (MODIS) sensor on the Aqua platform. In general, the data-mining approach produced estimates with low relative error (5 to 10%) and statistically significant correlations when compared against geostationary observations. This approach will facilitate global, near real-time applications of ALEXI at higher spatial and temporal coverage from a single sensor than currently achievable with current geostationary datasets.

Determinants of antiretroviral therapy coverage in Sub-Saharan Africa

PubMed Central

Hoque, Mohammad Zahirul

2015-01-01

Among 35 million people living with the human immunodeficiency virus (HIV) in 2013, only 37% had access to antiretroviral therapy (ART). Despite global concerted efforts to provide the universal access to the ART treatment, the ART coverage varies among countries and regions. At present, there is a lack of systematic empirical analyses on factors that determine the ART coverage. Therefore, the current study aimed to identify the determinants of the ART coverage in 41 countries in Sub-Saharan Africa. It employed statistical analyses for this purpose. Four elements, namely, the HIV prevalence, the level of national income, the level of medical expenditure and the number of nurses, were hypothesised to determine the ART coverage. The findings revealed that among the four proposed determinants only the HIV prevalence had a statistically significant impact on the ART coverage. In other words, the HIV prevalence was the sole determinant of the ART coverage in Sub-Saharan Africa. PMID:26664812

Global threshold dynamics of an SIVS model with waning vaccine-induced immunity and nonlinear incidence.

PubMed

Yang, Junyuan; Martcheva, Maia; Wang, Lin

2015-10-01

Vaccination is the most effective method of preventing the spread of infectious diseases. For many diseases, vaccine-induced immunity is not life long and the duration of immunity is not always fixed. In this paper, we propose an SIVS model taking the waning of vaccine-induced immunity and general nonlinear incidence into consideration. Our analysis shows that the model exhibits global threshold dynamics in the sense that if the basic reproduction number is less than 1, then the disease-free equilibrium is globally asymptotically stable implying the disease dies out; while if the basic reproduction number is larger than 1, then the endemic equilibrium is globally asymptotically stable indicating that the disease persists. This global threshold result indicates that if the vaccination coverage rate is below a critical value, then the disease always persists and only if the vaccination coverage rate is above the critical value, the disease can be eradicated. Copyright © 2015 Elsevier Inc. All rights reserved.

Geology of the Icy Galilean Satellites: Understanding Crustal Processes and Geologic Histories Through the JIMO Mission

NASA Technical Reports Server (NTRS)

Figueredo, P. H.; Tanaka, K.; Senske, D.; Greeley, R.

2003-01-01

Knowledge of the geology, style and time history of crustal processes on the icy Galilean satellites is necessary to understanding how these bodies formed and evolved. Data from the Galileo mission have provided a basis for detailed geologic and geo- physical analysis. Due to constrained downlink, Galileo Solid State Imaging (SSI) data consisted of global coverage at a -1 km/pixel ground sampling and representative, widely spaced regional maps at -200 m/pixel. These two data sets provide a general means to extrapolate units identified at higher resolution to lower resolution data. A sampling of key sites at much higher resolution (10s of m/pixel) allows evaluation of processes on local scales. We are currently producing the first global geological map of Europa using Galileo global and regional-scale data. This work is demonstrating the necessity and utility of planet-wide contiguous image coverage at global, regional, and local scales.

Need, Enabling, Predisposing, and Behavioral Determinants of Access to Preventative Care in Argentina: Analysis of the National Survey of Risk Factors

PubMed Central

Jahangir, Eiman; Irazola, Vilma; Rubinstein, Adolfo

2012-01-01

Introduction Health care utilization is an important step to disease management, providing opportunities for prevention and treatment. Anderson’s Health Behavior Model has defined utilization by need, predisposing, and enabling determinants. We hypothesize that need, predisposing, and enabling, highlighting behavioral factors are associated with utilization in Argentina. Methods We performed a logistic regression analysis of the 2005 and 2009 Argentinean Survey of Risk Factors, a cohort of 41,392 and 34,732 individuals, to explore the association between need, enabling, predisposing, and behavioral factors to blood pressure measurement in the last year. Results In the 2005 cohort, blood pressure measurement was associated with perception of health, insurance coverage, basic needs met, and income. Additionally, female sex, civil state, household type, older age groups, education, and alcohol use were associated with utilization. The 2009 cohort showed similar associations with only minor differences between the models. Conclusions We explored the association between utilization of clinical preventive services with need, enabling, predisposing, and behavioral factors. While predisposing and need determinants are associated with utilization, enabling factors such as insurance coverage provides an area for public intervention. These are important findings where policies should be focused to improve utilization of preventive services in Argentina. PMID:22984608

Volume CT (VCT) enabled by a novel diode technology

NASA Astrophysics Data System (ADS)

Ikhlef, Aziz; Zeman, Greg; Hoffman, David; Li, Wen; Possin, George

2005-04-01

One of the results of the latest developments in x-ray tube and detector technology, is the enabling of computed tomography (CT) as a strong non-invasive imaging modality for a new set of clinical applications including cardiac and brain imaging. A common theme among the applications is an ability to have wide anatomical coverage in a single rotation. Large coverage in CT is expected to bring significant diagnostic value in clinical field, especially in cardiac, trauma, pediatric, neuro, angiography, Stroke WorkUp and pulmonary applications. This demand, in turn, creates a need for tile-able and scalable detector design. In this paper, we introduce the design of a new diode, a crucial part of the detector, discuss how it enables wide coverage, its performance in terms of cross-talk, light output response, maximized geometric efficiency, and other CT requirements, and compare it to the traditional design which is front-illuminated diode. We ran extensive simulation and measurement experiments to study the geometric efficiency and assess the cross talk and all other performance parameters Critical To Quality (CTQs) with both designs. We modeled x-ray scattering in the scintillator, light scattering through the septa and optical coupler, and electrical cross talk. We tested the design with phantoms and clinical experiments on a scanner (LightSpeed VCT, GE Healthcare Technologies, Waukesha, WI, USA). Our preliminary results indicate that the new diode design performs as well as the traditional in terms of cross talk and other CTQs. It, also, yields better geometric efficiency and enables tile-able detector design, which is crucial for the VCT. We introduced a new diode design, which is an essential enabler for VCT. We demonstrated the new design is superior to the traditional design for the clinically relevant performance measures.

Quantifying Globalization in Social Work Research: A 10-Year Review of American Social Work Journals

ERIC Educational Resources Information Center

Agbényiga, DeBrenna L.; Huang, Lihua

2014-01-01

Measured by the prevalence of journal article contributions, geographic coverage, and international collaboration, this literature review found an increasing level of globalization with respect to American social work research and contribution to the social work profession from 2000-2009. Findings suggest changes are needed in global awareness and…

A Global Map of Thermal Inertia from Mars Global Surveyor Mapping-Mission Data

NASA Technical Reports Server (NTRS)

Mellon, M. T.; Kretke, K. A.; Smith, M. D.; Pelkey, S. M.

2002-01-01

TES (thermal emission spectrometry) has obtained high spatial resolution surface temperature observations from which thermal inertia has been derived. Seasonal coverage of these data now provides a nearly global view of Mars, including the polar regions, at high resolution. Additional information is contained in the original extended abstract.

Self-enforcing regional vaccination agreements

PubMed Central

Klepac, Petra; Grenfell, Bryan T.; Laxminarayan, Ramanan

2016-01-01

In a highly interconnected world, immunizing infections are a transboundary problem, and their control and elimination require international cooperation and coordination. In the absence of a global or regional body that can impose a universal vaccination strategy, each individual country sets its own strategy. Mobility of populations across borders can promote free-riding, because a country can benefit from the vaccination efforts of its neighbours, which can result in vaccination coverage lower than the global optimum. Here we explore whether voluntary coalitions that reward countries that join by cooperatively increasing vaccination coverage can solve this problem. We use dynamic epidemiological models embedded in a game-theoretic framework in order to identify conditions in which coalitions are self-enforcing and therefore stable, and thus successful at promoting a cooperative vaccination strategy. We find that countries can achieve significantly greater vaccination coverage at a lower cost by forming coalitions than when acting independently, provided a coalition has the tools to deter free-riding. Furthermore, when economically or epidemiologically asymmetric countries form coalitions, realized coverage is regionally more consistent than in the absence of coalitions. PMID:26790996

Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry.

PubMed

Ejsing, Christer S; Sampaio, Julio L; Surendranath, Vineeth; Duchoslav, Eva; Ekroos, Kim; Klemm, Robin W; Simons, Kai; Shevchenko, Andrej

2009-02-17

Although the transcriptome, proteome, and interactome of several eukaryotic model organisms have been described in detail, lipidomes remain relatively uncharacterized. Using Saccharomyces cerevisiae as an example, we demonstrate that automated shotgun lipidomics analysis enabled lipidome-wide absolute quantification of individual molecular lipid species by streamlined processing of a single sample of only 2 million yeast cells. By comparative lipidomics, we achieved the absolute quantification of 250 molecular lipid species covering 21 major lipid classes. This analysis provided approximately 95% coverage of the yeast lipidome achieved with 125-fold improvement in sensitivity compared with previous approaches. Comparative lipidomics demonstrated that growth temperature and defects in lipid biosynthesis induce ripple effects throughout the molecular composition of the yeast lipidome. This work serves as a resource for molecular characterization of eukaryotic lipidomes, and establishes shotgun lipidomics as a powerful platform for complementing biochemical studies and other systems-level approaches.

Improving cold chain systems: Challenges and solutions.

PubMed

Ashok, Ashvin; Brison, Michael; LeTallec, Yann

2017-04-19

While a number of new vaccines have been rolled out across the developing world (with more vaccines in the pipeline), cold chain systems are struggling to efficiently support national immunization programs in ensuring the availability of safe and potent vaccines. This article reflects on the Clinton Health Access Initiative, Inc. (CHAI) experience working since 2010 with national immunization programs and partners to improve vaccines cold chains in 10 countries-Ethiopia, Nigeria, Kenya, Malawi, Tanzania, Uganda, Cameroon, Mozambique, Lesotho and India - to identify the root causes and solutions for three common issues limiting cold chain performance. Key recommendations include: Collectively, the solutions detailed in this article chart a path to substantially improving the performance of the cold chain. Combined with an enabling global and in-country environment, it is possible to eliminate cold chain issues as a substantial barrier to effective and full immunization coverage over the next few years. Copyright © 2017. Published by Elsevier Ltd.

An enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins.

PubMed

Xiao, Haopeng; Chen, Weixuan; Smeekens, Johanna M; Wu, Ronghu

2018-04-27

Protein glycosylation is ubiquitous in biological systems and essential for cell survival. However, the heterogeneity of glycans and the low abundance of many glycoproteins complicate their global analysis. Chemical methods based on reversible covalent interactions between boronic acid and glycans have great potential to enrich glycopeptides, but the binding affinity is typically not strong enough to capture low-abundance species. Here, we develop a strategy using dendrimer-conjugated benzoboroxole to enhance the glycopeptide enrichment. We test the performance of several boronic acid derivatives, showing that benzoboroxole markedly increases glycopeptide coverage from human cell lysates. The enrichment is further improved by conjugating benzoboroxole to a dendrimer, which enables synergistic benzoboroxole-glycan interactions. This robust and simple method is highly effective for sensitive glycoproteomics analysis, especially capturing low-abundance glycopeptides. Importantly, the enriched glycopeptides remain intact, making the current method compatible with mass-spectrometry-based approaches to identify glycosylation sites and glycan structures.

Action to address the household economic burden of non-communicable diseases.

PubMed

Jan, Stephen; Laba, Tracey-Lea; Essue, Beverley M; Gheorghe, Adrian; Muhunthan, Janani; Engelgau, Michael; Mahal, Ajay; Griffiths, Ulla; McIntyre, Diane; Meng, Qingyue; Nugent, Rachel; Atun, Rifat

2018-05-19

The economic burden on households of non-communicable diseases (NCDs), including cardiovascular diseases, cancer, respiratory diseases, and diabetes, poses major challenges to global poverty alleviation efforts. For patients with NCDs, being uninsured is associated with 2-7-fold higher odds of catastrophic levels of out-of-pocket costs; however, the protection offered by health insurance is often incomplete. To enable coverage of the predictable and long-term costs of treatment, national programmes to extend financial protection should be based on schemes that entail compulsory enrolment or be financed through taxation. Priority should be given to eliminating financial barriers to the uptake of and adherence to interventions that are cost-effective and are designed to help the poor. In concert with programmes to strengthen national health systems and governance arrangements, comprehensive financial protection against the growing burden of NCDs is crucial in meeting the UN's Sustainable Development Goals. Copyright © 2018 Elsevier Ltd. All rights reserved.

A review of cellphone microscopy for disease detection.

PubMed

Dendere, R; Myburg, N; Douglas, T S

2015-12-01

The expansion in global cellphone network coverage coupled with advances in cellphone imaging capabilities present an opportunity for the advancement of cellphone microscopy as a low-cost alternative to conventional microscopy for disease detection in resource-limited regions. The development of cellphone microscopy has also benefitted from the availability of low-cost miniature microscope components such as low-power light-emitting diodes and ball lenses. As a result, researchers are developing hardware and software techniques that would enable such microscopes to produce high-resolution, diagnostic-quality images. This approach may lead to more widespread delivery of diagnostic services in resource-limited areas where there is a shortage of the skilled labour required for conventional microscopy and where prevalence of infectious and other diseases is still high. In this paper, we review current techniques, clinical applications and challenges faced in the field of cellphone microscopy. © 2015 The Authors Journal of Microscopy © 2015 Royal Microscopical Society.

Universal Health Coverage – The Critical Importance of Global Solidarity and Good Governance

PubMed Central

Reis, Andreas A.

2016-01-01

This article provides a commentary to Ole Norheim’ s editorial entitled "Ethical perspective: Five unacceptable trade-offs on the path to universal health coverage." It reinforces its message that an inclusive, participatory process is essential for ethical decision-making and underlines the crucial importance of good governance in setting fair priorities in healthcare. Solidarity on both national and international levels is needed to make progress towards the goal of universal health coverage (UHC). PMID:27694683

Arctic shipping emissions inventories and future scenarios

NASA Astrophysics Data System (ADS)

Corbett, J. J.; Lack, D. A.; Winebrake, J. J.; Harder, S.; Silberman, J. A.; Gold, M.

2010-10-01

This paper presents 5 km×5 km Arctic emissions inventories of important greenhouse gases, black carbon and other pollutants under existing and future (2050) scenarios that account for growth of shipping in the region, potential diversion traffic through emerging routes, and possible emissions control measures. These high-resolution, geospatial emissions inventories for shipping can be used to evaluate Arctic climate sensitivity to black carbon (a short-lived climate forcing pollutant especially effective in accelerating the melting of ice and snow), aerosols, and gaseous emissions including carbon dioxide. We quantify ship emissions scenarios which are expected to increase as declining sea ice coverage due to climate change allows for increased shipping activity in the Arctic. A first-order calculation of global warming potential due to 2030 emissions in the high-growth scenario suggests that short-lived forcing of ~4.5 gigagrams of black carbon from Arctic shipping may increase global warming potential due to Arctic ships' CO2 emissions (~42 000 gigagrams) by some 17% to 78%. The paper also presents maximum feasible reduction scenarios for black carbon in particular. These emissions reduction scenarios will enable scientists and policymakers to evaluate the efficacy and benefits of technological controls for black carbon, and other pollutants from ships.

Cross layer optimization for cloud-based radio over optical fiber networks

NASA Astrophysics Data System (ADS)

Shao, Sujie; Guo, Shaoyong; Qiu, Xuesong; Yang, Hui; Meng, Luoming

2016-07-01

To adapt the 5G communication, the cloud radio access network is a paradigm introduced by operators which aggregates all base stations computational resources into a cloud BBU pool. The interaction between RRH and BBU or resource schedule among BBUs in cloud have become more frequent and complex with the development of system scale and user requirement. It can promote the networking demand among RRHs and BBUs, and force to form elastic optical fiber switching and networking. In such network, multiple stratum resources of radio, optical and BBU processing unit have interweaved with each other. In this paper, we propose a novel multiple stratum optimization (MSO) architecture for cloud-based radio over optical fiber networks (C-RoFN) with software defined networking. Additionally, a global evaluation strategy (GES) is introduced in the proposed architecture. MSO can enhance the responsiveness to end-to-end user demands and globally optimize radio frequency, optical spectrum and BBU processing resources effectively to maximize radio coverage. The feasibility and efficiency of the proposed architecture with GES strategy are experimentally verified on OpenFlow-enabled testbed in terms of resource occupation and path provisioning latency.

Global dynamics of a mathematical model for the possible re-emergence of polio.

PubMed

Dénes, Attila; Székely, László

2017-11-01

Motivated by studies warning about a possible re-emergence of poliomyelitis in Europe, we analyse a compartmental model for the transmission of polio describing the possible effect of unvaccinated people arriving to a region with low vaccination coverage. We calculate the basic reproduction number, and determine the global dynamics of the system: we show that, depending on the parameters, one of the two equilibria is globally asymptotically stable. The main tools applied are Lyapunov functions and persistence theory. We illustrate the analytic results by numerical examples, which also suggest that in order to avoid the risk of polio re-emergence, vaccinating the immigrant population might result insufficient, and also the vaccination coverage of countries with low rates should be increased. Copyright © 2017 Elsevier Inc. All rights reserved.

The HYSPIRI Decadal Survey Mission: Update on the Mission Concept and Science Objectives for Global Imaging Spectroscopy and Multi-Spectral Thermal Measurements

NASA Technical Reports Server (NTRS)

Green, Robert O.; Hook, Simon J.; Middleton, Elizabeth; Turner, Woody; Ungar, Stephen; Knox, Robert

2012-01-01

The NASA HyspIRI mission is planned to provide global solar reflected energy spectroscopic measurement of the terrestrial and shallow water regions of the Earth every 19 days will all measurements downlinked. In addition, HyspIRI will provide multi-spectral thermal measurements with a single band in the 4 micron region and seven bands in the 8 to 12 micron region with 5 day day/night coverage. A direct broadcast capability for measurement subsets is also planned. This HyspIRI mission is one of those designated in the 2007 National Research Council (NRC) Decadal Survey: Earth Science and Applications from Space. In the Decadal Survey, HyspIRI was recognized as relevant to a range of Earth science and science applications, including climate: "A hyperspectral sensor (e.g., FLORA) combined with a multispectral thermal sensor (e.g., SAVII) in low Earth orbit (LEO) is part of an integrated mission concept [described in Parts I and II] that is relevant to several panels, especially the climate variability panel." The HyspIRI science study group was formed in 2008 to evaluate and refine the mission concept. This group has developed a series of HyspIRI science objectives: (1) Climate: Ecosystem biochemistry, condition & feedback; spectral albedo; carbon/dust on snow/ice; biomass burning; evapotranspiration (2) Ecosystems: Global plant functional types, physiological condition, and biochemistry including agricultural lands (3) Fires: Fuel status, fire frequency, severity, emissions, and patterns of recovery globally (4) Coral reef and coastal habitats: Global composition and status (5) Volcanoes: Eruptions, emissions, regional and global impact (6) Geology and resources: Global distributions of surface mineral resources and improved understanding of geology and related hazards These objectives are achieved with the following measurement capabilities. The HyspIRI imaging spectrometer provides: full spectral coverage from 380 to 2500 at 10 nm sampling; 60 m spatial sampling with a 150 km swath; and fully downlinked coverage of the Earth's terrestrial and shallow water regions every 19 days to provide seasonal cloud-free coverage of the terrestrial surface. The HyspIRI Multi-Spectral Thermal instrument provides: 8 spectral bands from 4 to 12 microns; 60 m spatial sampling with a 600 km swath; and fully downlinked coverage of the Earth's terrestrial shallow water regions every 5 days (day/night) to provide nominally cloud-free monthly coverage. The HyspIRI mission also includes an on-board processing and direct broadcast capability, referred to as the Intelligent Payload Module (IPM), which will allow users with the appropriate antenna to download a subset of the HyspIRI data stream to a local ground station. These science and science application objectives are critical today and uniquely addressed by the combined imaging spectroscopy, thermal infrared measurements, and IPM direct broadcast capability of HyspIRI. Two key objectives are: (1) The global HyspIRI spectroscopic measurements of the terrestrial biosphere including vegetation composition and function to constrain and reduce the uncertainty in climate-carbon interactions and terrestrial biosphere feedback. (2) The global 8 band thermal measurements to provide improved constraint of fire related emissions. In this paper the current HyspIRI mission concept that has been reviewed and refined to its current level of maturity with a Data Products Symposium, Science Workshop and NASA HWorkshop is presented including traceability between the measurements and the science and science application objectives.

Satellite Remote Sensing of Cirrus: An Overview

NASA Technical Reports Server (NTRS)

Minnis, Patrick

1998-01-01

The determination of cirrus properties over relatively large spatial and temporal scales will, in most instances, require the use of satellite data. Global coverage, at resolutions as high as several meters are attainable with Landsat, while temporal coverage at 1-min intervals is now available with the latest Geostationary Operational Environmental Satellite (GOES) imagers. Cirrus can be analyzed via interpretation of the radiation that they reflect or emit over a wide range of the electromagnetic spectrum. Many of these spectra and high-resolution satellite data can be used to understand certain aspects of cirrus clouds in particular situations. Production of a global climatology of cirrus clouds, however, requires compromises in spatial, temporal, and spectral coverage. This paper summarizes the state of the art and the potential for future passive remote sensing systems for both understanding cirrus formation and acquiring sufficient statistics to constrain and refine weather and climate models.

Leveraging paraprofessionals and family strengths to improve coverage and penetration of nutrition and early child development services.

PubMed

Tomlinson, Mark; Rahman, Atif; Sanders, David; Maselko, Joanna; Rotheram-Borus, Mary Jane

2014-01-01

Children need to be protected in intergenerational networks, with parents who have positive mood, resources to feed their children, and skills to promote early childhood development (ECD). Globally, more than 200 million children are raised annually without these resources. This article reviews the potential contributions of increasing coverage and penetration of services for these children, challenges to achieving penetration of services in high-risk families, opportunities created by bundling multiple services within one provider, potential leveraging of paraprofessionals to deliver care, and mobilizing communities to support children in households at high risk for negative outcomes. We end with a number of suggestions for how to ensure the equitable scale-up of integrated ECD and nutrition services that take into account current global priorities, as well as coverage and penetration of services. © 2013 New York Academy of Sciences.

Progress in global measles control, 2000-2010.

PubMed

2012-02-03

In 1980, before widespread global use of measles vaccine, an estimated 2.6 million measles deaths occurred worldwide. In 2001, to accelerate the reduction in measles cases achieved by vaccination, the World Health Organization (WHO) and the United Nations Children's Fund (UNICEF) developed a strategy to deliver 2 doses of measles-containing vaccine (MCV) to all children through routine services and supplementary immunization activities (SIAs) and improved disease surveillance. After implementation of this strategy, the estimated number of annual measles deaths worldwide decreased from 733,000 in 2000 to 164,000 in 2008. In 2010, the World Health Assembly endorsed the following measles objectives for 2015: 1) raise routine coverage with the first dose of MCV (MCV1) for children aged 1 year to ≥90% nationally and ≥80% in every district or equivalent administrative unit, 2) reduce and maintain annual measles incidence at <5 cases per million, and 3) reduce measles mortality by ≥95% from the 2000 estimate. During 2000-2010, global MCV1 coverage increased from 72% to 85% with approximately 1 billion children vaccinated during measles SIAs. Reported measles cases decreased from 2000 to 2008, remained stable in 2009, and increased in 2010. By the end of 2010, 40% of countries still had not met the incidence target of <5 cases per million. Key challenges must be overcome to meet the 2015 objectives, including 1) declining political and financial commitments to measles control, 2) failure to reach uniform high coverage with 2 doses of MCV through routine services or SIAs, and 3) inadequate monitoring subnationally of coverage with the first and second dose of MCV to guide interventions to increase coverage.

Accelerating progress towards universal health coverage in Asia and Pacific: improving the future for women and children

PubMed Central

Beattie, Allison; Yates, Robert; Noble, Douglas J

2016-01-01

Universal health coverage generates significant health and economic benefits and enables governments to reduce inequity. Where universal health coverage has been implemented well, it can contribute to nation-building. This analysis reviews evidence from Asia and Pacific drawing out determinants of successful systems and barriers to progress with a focus on women and children. Access to healthcare is important for women and children and contributes to early childhood development. Universal health coverage is a political process from the start, and public financing is critical and directly related to more equitable health systems. Closing primary healthcare gaps should be the foundation of universal health coverage reforms. Recommendations for policy for national governments to improve universal health coverage are identified, including countries spending < 3% of gross domestic product in public expenditure on health committing to increasing funding by at least 0.3%/year to reach a minimum expenditure threshold of 3%. PMID:28588989

Identifying low-coverage surface species on supported noble metal nanoparticle catalysts by DNP-NMR

DOE PAGES

Johnson, Robert L.; Perras, Frédéric A.; Kobayashi, Takeshi; ...

2015-11-20

DNP-NMR spectroscopy has been applied to enhance the signal for organic molecules adsorbed on γ-Al 2O 3-supported Pd nanoparticles. In addition, by offering >2500-fold time savings, the technique enabled the observation of 13C- 13C cross-peaks for low coverage species, which were assigned to products from oxidative degradation of methionine adsorbed on the nanoparticle surface.

Landsat Data Continuity Mission

USGS Publications Warehouse

,

2012-01-01

The Landsat Data Continuity Mission (LDCM) is a partnership formed between the National Aeronautics and Space Administration (NASA) and the U.S. Geological Survey (USGS) to place the next Landsat satellite in orbit in January 2013. The Landsat era that began in 1972 will become a nearly 41-year global land record with the successful launch and operation of the LDCM. The LDCM will continue the acquisition, archiving, and distribution of multispectral imagery affording global, synoptic, and repetitive coverage of the Earth's land surfaces at a scale where natural and human-induced changes can be detected, differentiated, characterized, and monitored over time. The mission objectives of the LDCM are to (1) collect and archive medium resolution (30-meter spatial resolution) multispectral image data affording seasonal coverage of the global landmasses for a period of no less than 5 years; (2) ensure that LDCM data are sufficiently consistent with data from the earlier Landsat missions in terms of acquisition geometry, calibration, coverage characteristics, spectral characteristics, output product quality, and data availability to permit studies of landcover and land-use change over time; and (3) distribute LDCM data products to the general public on a nondiscriminatory basis at no cost to the user.

Quad-Tree Visual-Calculus Analysis of Satellite Coverage

NASA Technical Reports Server (NTRS)

Lo, Martin W.; Hockney, George; Kwan, Bruce

2003-01-01

An improved method of analysis of coverage of areas of the Earth by a constellation of radio-communication or scientific-observation satellites has been developed. This method is intended to supplant an older method in which the global-coverage-analysis problem is solved from a ground-to-satellite perspective. The present method provides for rapid and efficient analysis. This method is derived from a satellite-to-ground perspective and involves a unique combination of two techniques for multiresolution representation of map features on the surface of a sphere.

AVHRR for monitoring global tropical deforestation

NASA Technical Reports Server (NTRS)

Malingreau, J. P.; Laporte, N.; Tucker, C. J.

1989-01-01

Advanced Very High Resolution Radiometer (AVHRR) data have been used to assess the dynamics of forest trnsformations in three parts of the tropical belt. A large portion of the Amazon Basin has been systematically covered by Local Area Coverage (LAC) data in the 1985-1987 period. The analysis of the vegetation index and thermal data led to the identification and measurement of large areas of active deforestation. The Kalimantan/Borneo forest fires were monitored and their impact was evaluated using the Global Area Coverage (GAC) 4 km resolution data. Finally, High Resolution Picture Transmission (HRPT) data have provided preliminary information on current activities taking place at the boundary between the savanna and the forest in the Southern part of West Africa. The AVHRR approach is found to be a highly valuable means for carrying out deforestation assessments in regional and global perspectives.

International Satellite Cloud Climatology Project (ISCCP) Ice Snow Product in Native (NAT) Format (ISCCP_ICESNOW_NAT)

NASA Technical Reports Server (NTRS)

Rossow, William B. (Principal Investigator)

Since 1983 an international group of institutions has collected and analyzed satellite radiance measurements from up to five geostationary and two polar orbiting satellites to infer the global distribution of cloud properties and their diurnal, seasonal and interannual variations. The primary focus of the first phase of the project (1983-1995) was the elucidation of the role of clouds in the radiation budget (top of the atmosphere and surface). In the second phase of the project (1995 onwards) the analysis also concerns improving understanding of clouds in the global hydrological cycle. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1983-07-01; Stop_Date=] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Latitude_Resolution=112 Km; Longitude_Resolution=112 Km; Temporal_Resolution=5-day].

CEOS Ocean Variables Enabling Research and Applications for Geo (COVERAGE)

NASA Astrophysics Data System (ADS)

Tsontos, V. M.; Vazquez, J.; Zlotnicki, V.

2017-12-01

The CEOS Ocean Variables Enabling Research and Applications for GEO (COVERAGE) initiative seeks to facilitate joint utilization of different satellite data streams on ocean physics, better integrated with biological and in situ observations, including near real-time data streams in support of oceanographic and decision support applications for societal benefit. COVERAGE aligns with programmatic objectives of CEOS (the Committee on Earth Observation Satellites) and the missions of GEO-MBON (Marine Biodiversity Observation Network) and GEO-Blue Planet, which are to advance and exploit synergies among the many observational programs devoted to ocean and coastal waters. COVERAGE is conceived of as 3 year pilot project involving international collaboration. It focuses on implementing technologies, including cloud based solutions, to provide a data rich, web-based platform for integrated ocean data delivery and access: multi-parameter observations, easily discoverable and usable, organized by disciplines, available in near real-time, collocated to a common grid and including climatologies. These will be complemented by a set of value-added data services available via the COVERAGE portal including an advanced Web-based visualization interface, subsetting/extraction, data collocation/matchup and other relevant on demand processing capabilities. COVERAGE development will be organized around priority use cases and applications identified by GEO and agency partners. The initial phase will be to develop co-located 25km products from the four Ocean Virtual Constellations (VCs), Sea Surface Temperature, Sea Level, Ocean Color, and Sea Surface Winds. This aims to stimulate work among the ocean VCs while developing products and system functionality based on community recommendations. Such products as anomalies from a time mean, would build on the theme of applications with a relevance to CEOS/GEO mission and vision. Here we provide an overview of the COVERAGE initiative with an emphasis on international collaborative aspects entailed with the intent of soliciting community feedback as we develop and implement

Right Technology, Right Now: An Evaluation Methodology for Rapidly Deployable Information and Communications Technologies in Humanitarian Assistance/Disaster Relief

DTIC Science & Technology

2012-03-01

30  c.  IEEE 802.16/WiMAX .............................................................31  4.  Broadband Global Area Network...Space Agency, 2006) ...........................34  Figure 19.  Global BGAN Coverage (From Inmarsat, 2009...BGAN Broadband Global Area Network C2 Command and Control CHSC California Homeland Security Consortium CIE Collaborative Information Environment CJCS

Industrial application for global quantum communication

NASA Astrophysics Data System (ADS)

Mirza, A.; Petruccione, F.

2012-09-01

In the last decade the quantum communication community has witnessed great advances in photonic quantum cryptography technology with the research, development and commercialization of automated Quantum Key Distribution (QKD) devices. These first generation devices are however bottlenecked by the achievable spatial coverage. This is due to the intrinsic absorption of the quantum particle into the communication medium. As QKD is of paramount importance in the future ICT landscape, various innovative solutions have been developed and tested to expand the spatial coverage of these networks such as the Quantum City initiative in Durban, South Africa. To expand this further into a global QKD-secured network, recent efforts have focussed on high-altitude free-space techniques through the use of satellites. This couples the QKD-secured Metropolitan Area Networks (MANs) with secured ground-tosatellite links as access points to a global network. Such a solution, however, has critical limitations that reduce its commercial feasibility. As parallel step to the development of satellitebased global QKD networks, we investigate the use of the commercial aircrafts' network as secure transport mechanisms in a global QKD network. This QKD-secured global network will provide a robust infrastructure to create, distribute and manage encryption keys between the MANs of the participating cities.

Shifts in global immunisation goals (1984-2004): unfinished agendas and mixed results.

PubMed

Hardon, Anita; Blume, Stuart

2005-01-01

The turn of the millennium has been marked by a large-scale mobilisation of resources for immunisation programmes in developing countries. The resources have been generated by public and private sector parties collaborating in the Global Alliance for Vaccines and Immunization (GAVI). GAVI was formed in response to deteriorating immunisation coverage rates occurring in the late 1990s. GAVI is the latest in a line of vaccine initiatives, which have operated over the past 20 years. This article reviews the five most important global immunisation initiatives that have taken place over those past 20 years. It analyses their origins, shifts in global immunisation goals, identifies key actors, assesses the initiatives' capacity to mobilise resources and increase immunisation coverage, and points to possible unintended effects of the initiatives. The study argues that shifts in global immunisation goals lead to fragmentation in the implementation of vaccine programmes at the local level in developing countries. It also suggests that global actors involved in the formulation of these initiatives appear to miss opportunities to build on past experiences and fail to learn from previous mistakes. This raises questions about the initiatives' sustainability and relevance to the overall objective of preventing vaccine-preventable deaths.

Health status and health systems financing in the MENA region: roadmap to universal health coverage.

PubMed

Asbu, Eyob Zere; Masri, Maysoun Dimachkie; Kaissi, Amer

2017-01-01

Since the declaration of the Millennium Development Goals (MDGs) in 1990, many countries of the Middle East and North Africa (MENA) region made some improvements in maternal and child health and in tackling communicable diseases. The transition to the global agenda of Sustainable Development Goals brings new opportunities for countries to move forward toward achieving progress for better health, well-being, and universal health coverage. This study provides a profile of health status and health financing approaches in the MENA region and their implications on universal health coverage. Time-series data on socioeconomics, health expenditures, and health outcomes were extracted from databases and reports of the World Health Organization, the World Bank and the United Nations Development Program and analyzed using Stata 12 statistical software. Countries were grouped according to the World Bank income categories. Descriptive statistics, tables and charts were used to analyze temporal changes and compare the key variables with global averages. Non-communicable diseases (NCDs) and injuries account for more than three quarters of the disability-adjusted life years in all but two lower middle-income countries (Sudan and Yemen). Prevalence of risk factors (raised blood glucose, raised blood pressure, obesity and smoking) is higher than global averages and counterparts by income group. Total health expenditure (THE) per capita in most of the countries falls short of global averages for countries under similar income category. Furthermore, growth rate of THE per capita has not kept pace with the growth rate of GDP per capita. Out-of-pocket spending (OOPS) in all but the high-income countries in the group exceeds the threshold for catastrophic spending implying that there is a high risk of households getting poorer as a result of paying for health care. The alarmingly high prevalence of NCDs and injuries and associated risk factors, health spending falling short of the GDP and GDP growth rate, and high OOPS pose serious challenges for universal health coverage. Using multi-sector interventions, countries should develop and implement evidence-informed health system financing roadmaps to address these obstacles and move forward toward universal health coverage.

Changes in Arctic and Antarctic Sea Ice as a Microcosm of Global Climate Change

NASA Technical Reports Server (NTRS)

Parkinson, Claire L.

2014-01-01

Polar sea ice is a key element of the climate system and has now been monitored through satellite observations for over three and a half decades. The satellite observations reveal considerable information about polar ice and its changes since the late 1970s, including a prominent downward trend in Arctic sea ice coverage and a much lesser upward trend in Antarctic sea ice coverage, illustrative of the important fact that climate change entails spatial contrasts. The decreasing ice coverage in the Arctic corresponds well with contemporaneous Arctic warming and exhibits particularly large decreases in the summers of 2007 and 2012, influenced by both preconditioning and atmospheric conditions. The increasing ice coverage in the Antarctic is not as readily explained, but spatial differences in the Antarctic trends suggest a possible connection with atmospheric circulation changes that have perhaps been influenced by the Antarctic ozone hole. The changes in the polar ice covers and the issues surrounding those changes have many commonalities with broader climate changes and their surrounding issues, allowing the sea ice changes to be viewed in some important ways as a microcosm of global climate change.

Swath sonar mapping of Earth's submarine plate boundaries

NASA Astrophysics Data System (ADS)

Carbotte, S. M.; Ferrini, V. L.; Celnick, M.; Nitsche, F. O.; Ryan, W. B. F.

2014-12-01

The recent loss of Malaysia Airlines flight MH370 in an area of the Indian Ocean where less than 5% of the seafloor is mapped with depth sounding data (Smith and Marks, EOS 2014) highlights the striking lack of detailed knowledge of the topography of the seabed for much of the worlds' oceans. Advances in swath sonar mapping technology over the past 30 years have led to dramatic improvements in our capability to map the seabed. However, the oceans are vast and only an estimated 10% of the seafloor has been mapped with these systems. Furthermore, the available coverage is highly heterogeneous and focused within areas of national strategic priority and community scientific interest. The major plate boundaries that encircle the globe, most of which are located in the submarine environment, have been a significant focus of marine geoscience research since the advent of swath sonar mapping. While the location of these plate boundaries are well defined from satellite-derived bathymetry, significant regions remain unmapped at the high-resolutions provided by swath sonars and that are needed to study active volcanic and tectonic plate boundary processes. Within the plate interiors, some fossil plate boundary zones, major hotspot volcanoes, and other volcanic provinces have been the focus of dedicated research programs. Away from these major tectonic structures, swath mapping coverage is limited to sparse ocean transit lines which often reveal previously unknown deep-sea channels and other little studied sedimentary structures not resolvable in existing low-resolution global compilations, highlighting the value of these data even in the tectonically quiet plate interiors. Here, we give an overview of multibeam swath sonar mapping of the major plate boundaries of the globe as extracted from public archives. Significant quantities of swath sonar data acquired from deep-sea regions are in restricted-access international archives. Open access to more of these data sets would enable global comparisons of plate boundary structures and processes and could facilitate a more coordinated approach to optimizing the future acquisition of these high-value data by the global research community.

Linking THEMIS Orbital Data to MSL GTS Measurements: The Thermophysical Properties of the Bagnold Dunes, Mars

NASA Astrophysics Data System (ADS)

Edwards, C. S.; Piqueux, S.; Hamilton, V. E.; Fergason, R. L.; Herkenhoff, K. E.; Vasavada, A. R.; Sacks, L. E.; Lewis, K. W.; Smith, M. D.

2017-12-01

The surface of Mars has been characterized using orbital thermal infrared observations from the time of the Mariner 9 and Viking missions. More recent observations from missions such as the Thermal Emission Spectrometer onboard the Mars Global Surveyor and the Thermal Emission Imaging System (THEMIS) instrument onboard the 2001 Mars Odyssey orbiter have continued to expand global coverage at progressively higher resolution. THEMIS has been producing 100 m/pixel thermal infrared data with nearly global coverage of the surface for >15 years and has enabled new investigations that successfully link outcrop-scale information to physical properties of the surface. However, significant discrepancies between morphologies and interpreted surface properties derived from orbital thermal measurements remain, requiring a robust link to direct surface measurements. Here, we compare the thermophysical properties and particle sizes derived from the Mars Science Laboratory (MSL) rover's Ground Temperature Sensor (GTS), to those derived orbitally from THEMIS, ultimately linking these measurements to ground truth particle sizes determined from Mars Hand Lens Imager (MAHLI) images. We focus on the relatively homogenous Bagnold dunes, specifically Namib dune, and in general find that all three datasets report consistent particle sizes for the Bagnold dunes ( 110-350 µm, and are within measurement and model uncertainties), indicating that particles sizes of homogeneous materials determined from thermal measurements are reliable. In addition, we assess several potentially significant effects that could influence the derived particle sizes, including: 1) fine-scale (cm-m scale) ripples, and 2) thin (mm-cm) layering of indurated/armored materials. To first order, we find that small scale ripples and thin layers do not significantly affect the determination of bulk thermal inertia determined from orbit. However, a layer of coarser/indurated material and/or fine-scale layering does change the shape of a diurnal curve and thus requires multiple time of day observations to constrain these effects. In summary, thermal inertia and grain sizes of relatively homogeneous materials derived from nighttime orbital data should be considered as reliable, as long as there is not significant sub-pixel anisothermality.

Using lot quality assurance sampling to improve immunization coverage in Bangladesh.

PubMed Central

Tawfik, Y.; Hoque, S.; Siddiqi, M.

2001-01-01

OBJECTIVE: To determine areas of low vaccination coverage in five cities in Bangladesh (Chittagong, Dhaka, Khulna, Rajshahi, and Syedpur). METHODS: Six studies using lot quality assurance sampling were conducted between 1995 and 1997 by Basic Support for Institutionalizing Child Survival and the Bangladesh National Expanded Programme on Immunization. FINDINGS: BCG vaccination coverage was acceptable in all lots studied; however, the proportion of lots rejected because coverage of measles vaccination was low ranged from 0% of lots in Syedpur to 12% in Chittagong and 20% in Dhaka's zones 7 and 8. The proportion of lots rejected because an inadequate number of children in the sample had been fully vaccinated varied from 11% in Syedpur to 30% in Dhaka. Additionally, analysis of aggregated, weighted immunization coverage showed that there was a high BCG vaccination coverage (the first administered vaccine) and a low measles vaccination coverage (the last administered vaccine) indicating a high drop-out rate, ranging from 14% in Syedpur to 36% in Dhaka's zone 8. CONCLUSION: In Bangladesh, where resources are limited, results from surveys using lot quality assurance sampling enabled managers of the National Expanded Programme on Immunization to identify areas with poor vaccination coverage. Those areas were targeted to receive focused interventions to improve coverage. Since this sampling method requires only a small sample size and was easy for staff to use, it is feasible for routine monitoring of vaccination coverage. PMID:11436470

Coupled fvGCM-GCE Modeling System, 3D Cloud-Resolving Model and Cloud Library

NASA Technical Reports Server (NTRS)

Tao, Wei-Kuo

2005-01-01

Recent GEWEX Cloud System Study (GCSS) model comparison projects have indicated that cloud-resolving models (CRMs) agree with observations better than traditional singlecolumn models in simulating various types of clouds and cloud systems from Merent geographic locations. Current and future NASA satellite programs can provide cloud, precipitation, aerosol and other data at very fine spatial and temporal scales. It requires a coupled global circulation model (GCM) and cloudscale model (termed a super-parameterization or multiscale modeling framework, MMF) to use these satellite data to improve the understanding of the physical processes that are responsible for the variation in global and regional climate and hydrological systems. The use of a GCM will enable global coverage, and the use of a CRM will allow for better and more sophisticated physical parameteridon NASA satellite and field campaign cloud related datasets can provide initial conditions as well as validation for both the MMF and CRMs. A seed fund is available at NASA Goddard to build a MMF based on the 2D Goddard cumulus Ensemble (GCE) model and the Goddard finite volume general circulation model (fvGCM). A prototype MMF in being developed and production nms will be conducted at the beginning of 2005. In this talk, I will present: (1) A brief review on GCE model and its applications on precipitation processes, (2) The Goddard MMF and the major difference between two existing MMFs (CSU MMF and Goddard MMF), (3) A cloud library generated by Goddard MMF, and 3D GCE model, and (4) A brief discussion on the GCE model on developing a global cloud simulator.

Undernutrition, poor feeding practices, and low coverage of key nutrition interventions.

PubMed

Lutter, Chessa K; Daelmans, Bernadette M E G; de Onis, Mercedes; Kothari, Monica T; Ruel, Marie T; Arimond, Mary; Deitchler, Megan; Dewey, Kathryn G; Blössner, Monika; Borghi, Elaine

2011-12-01

To estimate the global burden of malnutrition and highlight data on child feeding practices and coverage of key nutrition interventions. Linear mixed-effects modeling was used to estimate prevalence rates and numbers of underweight and stunted children according to United Nations region from 1990 to 2010 by using surveys from 147 countries. Indicators of infant and young child feeding practices and intervention coverage were calculated from Demographic and Health Survey data from 46 developing countries between 2002 and 2008. In 2010, globally, an estimated 27% (171 million) of children younger than 5 years were stunted and 16% (104 million) were underweight. Africa and Asia have more severe burdens of undernutrition, but the problem persists in some Latin American countries. Few children in the developing world benefit from optimal breastfeeding and complementary feeding practices. Fewer than half of infants were put to the breast within 1 hour of birth, and 36% of infants younger than 6 months were exclusively breastfed. Fewer than one-third of 6- to 23-month-old children met the minimum criteria for dietary diversity, and only ∼50% received the minimum number of meals. Although effective health-sector-based interventions for tackling childhood undernutrition are known, intervention-coverage data are available for only a small proportion of them and reveal mostly low coverage. Undernutrition continues to be high and progress toward reaching Millennium Development Goal 1 has been slow. Previously unrecognized extremely poor breastfeeding and complementary feeding practices and lack of comprehensive data on intervention coverage require urgent action to improve child nutrition.

Feasibility of using global system for mobile communication (GSM)-based tracking for vaccinators to improve oral poliomyelitis vaccine campaign coverage in rural Pakistan.

PubMed

Chandir, Subhash; Dharma, Vijay Kumar; Siddiqi, Danya Arif; Khan, Aamir Javed

2017-09-05

Despite multiple rounds of immunization campaigns, it has not been possible to achieve optimum immunization coverage for poliovirus in Pakistan. Supplementary activities to improve coverage of immunization, such as door-to-door campaigns are constrained by several factors including inaccurate hand-drawn maps and a lack of means to objectively monitor field teams in real time, resulting in suboptimal vaccine coverage during campaigns. Global System for Mobile Communications (GSM) - based tracking of mobile subscriber identity modules (SIMs) of vaccinators provides a low-cost solution to identify missed areas and ensure effective immunization coverage. We conducted a pilot study to investigate the feasibility of using GSM technology to track vaccinators through observing indicators including acceptability, ease of implementation, costs and scalability as well as the likelihood of ownership by District Health Officials. The real-time location of the field teams was displayed on a GSM tracking web dashboard accessible by supervisors and managers for effective monitoring of workforce attendance including 'time in-time out', and discerning if all target areas - specifically remote and high-risk locations - had been reached. Direct access to this information by supervisors eliminated the possibility of data fudging and inaccurate reporting by workers regarding their mobility. The tracking cost per vaccinator was USD 0.26/month. Our study shows that GSM-based tracking is potentially a cost-efficient approach, results in better monitoring and accountability, is scalable and provides the potential for improved geographic coverage of health services. Copyright © 2017 Elsevier Ltd. All rights reserved.

Dental care coverage and income-related inequalities in foregone dental care in Europe during the great recession.

PubMed

Elstad, Jon Ivar

2017-08-01

This study examines income inequalities in foregone dental care in 23 European countries during the years with global economic crisis. Associations between dental care coverage from public health budgets or social insurance, and income-related inequalities in perceived access to dental care, are analysed. Survey data 2008-2013 from 23 countries were combined with country data on macro-economic conditions and coverage for dental care. Foregone dental care was defined as self-reported abstentions from needed dental care because of costs or other crisis-related reasons. Age-standardized percentages reporting foregone dental care were estimated for respondents, age 20-74, in the lowest and highest income quartile. Associations between dental care coverage and income inequalities in foregone dental care, adjusted for macro-economic indicators, were examined by country-level regression models. In all 23 countries, respondents in the lowest income quartile reported significantly higher levels of foregone dental care than respondents in the highest quartile. During 2008-2013, income inequalities in foregone dental care widened significantly in 13 of 23 countries, but decreased in only three countries. Adjusted for countries' macro-economic situation and severity of the economic crisis, higher dental care coverage was significantly associated with smaller income inequalities in foregone dental care and less widening of these inequalities. Income-related inequalities in dental care have widened in Europe during the years with global economic crisis. Higher dental care coverage corresponded to less income-related inequalities in foregone dental care and less widening of these inequalities. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Determinants of apparent rural-urban differentials in measles vaccination uptake in Indonesia.

PubMed

Fernandez, Renae C; Awofeso, Niyi; Rammohan, Anu

2011-01-01

Regional differences in vaccination uptake are common in both developed and developing countries, and are often linked to the availability of healthcare services and socioeconomic factors. In 2007, 0.9 million eligible Indonesian children missed measles vaccination, and 19 456 cases of measles were documented among Indonesian children. The authors investigated rural-urban differentials in measles vaccination coverage among young Indonesian children, and sought to identify key factors influencing the probability of a child receiving the first dose of measles vaccination in Indonesia. Data used in the analyses were sourced from the nationally representative Indonesia Demographic and Health Survey 2007. The influence of location of residence, household wealth, maternal and paternal education, total children ever born and use of skilled birth attendants on measles vaccination coverage was investigated using bivariate analysis and chi-square tests. The independent effects of these variables were established using binomial logistic regression analysis. Indonesia's 2007 first-dose measles national vaccination coverage was, at 72.8%, lower than the 2008 global first-dose measles vaccination average coverage of 82%. Bivariate analysis revealed that the first-dose measles vaccination coverage in rural areas of Indonesia was 68.5%, compared with 80.1% in urban regions (p < 0.001). The apparent significance of rural residence in impairing vaccination coverage was marginal after controlling for the sex of the child, maternal age, maternal and paternal education, wealth, and access to skilled health workers. Apart from sustainable initiatives to increase measles vaccination coverage globally, it is important to close the rural-urban gap in Indonesia's measles vaccination uptake. Addressing critical determinants of inferior measles vaccination coverage in Indonesia's rural regions will facilitate major improvements in Indonesia's child health trends. This article suggests initiatives for addressing three of such determinants in Indonesia's rural areas: poverty, parental education and access to skilled health workers.

Orbit dynamics and geographical coverage capabilities of satellite-based solar occultation experiments for global monitoring of stratospheric constituents

NASA Technical Reports Server (NTRS)

Brooks, D. R.

1980-01-01

Orbit dynamics of the solar occultation technique for satellite measurements of the Earth's atmosphere are described. A one-year mission is simulated and the orbit and mission design implications are discussed in detail. Geographical coverage capabilities are examined parametrically for a range of orbit conditions. The hypothetical mission is used to produce a simulated one-year data base of solar occultation measurements; each occultation event is assumed to produce a single number, or 'measurement' and some statistical properties of the data set are examined. A simple model is fitted to the data to demonstrate a procedure for examining global distributions of atmospheric constitutents with the solar occultation technique.

Population-based HPV vaccination programmes are safe and effective: 2017 update and the impetus for achieving better global coverage.

PubMed

Brotherton, Julia M L; Bloem, Paul N

2018-02-01

Persistent oncogenic human papillomavirus (HPV) is the cause of cervical cancer, as well as cancers of the anus, penis, vulva, vagina and oropharynx. There is good evidence that prophylactic HPV vaccines are immunogenic and effective against targeted-type HPV infections and type-specific genital lesions, including high-grade cervical intraepithelial neoplasia (CIN), when administered prior to HPV infection. There is good evidence that HPV vaccines are safe in population usage, with the most frequent adverse event being injection-site reactions. There is evidence to support some cross-protection against non-targeted types occurring following the administration of HPV vaccines. There is limited evidence suggesting that HPV vaccines may be beneficial in preventing future disease in women treated for high-grade CIN. This chapter focuses on the accumulated evidence regarding the global use of the three licensed HPV vaccines including safety, immunogenicity, duration of protection, effectiveness, coverage to date and barriers to higher coverage. Copyright © 2018 Elsevier Ltd. All rights reserved.

Satellite orbit considerations for a global change technology architecture trade study

NASA Technical Reports Server (NTRS)

Harrison, Edwin F.; Gibson, Gary G.; Suttles, John T.; Buglia, James J.; Taback, Israel

1991-01-01

A study was conducted to determine satellite orbits for earth observation missions aimed at obtaining data for assessing data global climate change. A multisatellite system is required to meet the scientific requirements for temporal coverage over the globe. The best system consists of four sun-synchronous satellites equally spaced in local time of equatorial crossing. This system can obtain data every three hours for all regions. Several other satellite systems consisting of combinations of sun-synchronous orbits and either the Space Station Freedom or a mid-altitude equatorial satellite can provide three to six hour temporal coverage, which is sufficient for measuring many of the parameters required for the global change monitoring mission. Geosynchronous satellites are required to study atmospheric and surface processes involving variations on the order of a few minutes to an hour. One or two geosynchronous satellites can be relocated in longitude to study processes over selected regions of earth.

3D model generation using an airborne swarm

DOE Office of Scientific and Technical Information (OSTI.GOV)

Clark, R. A.; Punzo, G.; Macdonald, M.

2015-03-31

Using an artificial kinematic field to provide co-ordination between multiple inspection UAVs, the authors herein demonstrate full 3D modelling capability based on a photogrammetric system. The operation of the system is demonstrated by generating a full 3D surface model of an intermediate level nuclear waste storage drum. Such drums require periodic inspection to ensure that drum distortion or corrosion is carefully monitored. Performing this inspection with multiple airborne platforms enables rapid inspection of structures that are inaccessible to on-surface remote vehicles and are in human-hazardous environments. A three-dimensional surface-meshed model of the target can then be constructed in post-processing throughmore » photogrammetry analysis of the visual inspection data. The inspection environment uses a tracking system to precisely monitor the position of each aerial vehicle within the enclosure. The vehicles used are commercially available Parrot AR. Drone quadcopters, controlled through a computer interface connected over an IEEE 802.11n (WiFi) network, implementing a distributed controller for each vehicle. This enables the autonomous and distributed elements of the control scheme to be retained, while alleviating the vehicles of the control algorithm’s computational load. The control scheme relies on a kinematic field defined with the target at its centre. This field defines the trajectory for all the drones in the volume relative to the central target, enabling the drones to circle the target at a set radius while avoiding drone collisions. This function enables complete coverage along the height of the object, which is assured by transitioning to another inspection band only after completing circumferential coverage. Using a swarm of vehicles, the time until complete coverage can be significantly reduced.« less

3D model generation using an airborne swarm

NASA Astrophysics Data System (ADS)

Clark, R. A.; Punzo, G.; Dobie, G.; MacLeod, C. N.; Summan, R.; Pierce, G.; Macdonald, M.; Bolton, G.

2015-03-01

Using an artificial kinematic field to provide co-ordination between multiple inspection UAVs, the authors herein demonstrate full 3D modelling capability based on a photogrammetric system. The operation of the system is demonstrated by generating a full 3D surface model of an intermediate level nuclear waste storage drum. Such drums require periodic inspection to ensure that drum distortion or corrosion is carefully monitored. Performing this inspection with multiple airborne platforms enables rapid inspection of structures that are inaccessible to on-surface remote vehicles and are in human-hazardous environments. A three-dimensional surface-meshed model of the target can then be constructed in post-processing through photogrammetry analysis of the visual inspection data. The inspection environment uses a tracking system to precisely monitor the position of each aerial vehicle within the enclosure. The vehicles used are commercially available Parrot AR. Drone quadcopters, controlled through a computer interface connected over an IEEE 802.11n (WiFi) network, implementing a distributed controller for each vehicle. This enables the autonomous and distributed elements of the control scheme to be retained, while alleviating the vehicles of the control algorithm's computational load. The control scheme relies on a kinematic field defined with the target at its centre. This field defines the trajectory for all the drones in the volume relative to the central target, enabling the drones to circle the target at a set radius while avoiding drone collisions. This function enables complete coverage along the height of the object, which is assured by transitioning to another inspection band only after completing circumferential coverage. Using a swarm of vehicles, the time until complete coverage can be significantly reduced.

Double-Difference Global Adjoint Tomography

NASA Astrophysics Data System (ADS)

Orsvuran, R.; Bozdag, E.; Lei, W.; Tromp, J.

2017-12-01

The adjoint method allows us to incorporate full waveform simulations in inverse problems. Misfit functions play an important role in extracting the relevant information from seismic waveforms. In this study, our goal is to apply the Double-Difference (DD) methodology proposed by Yuan et al. (2016) to global adjoint tomography. Dense seismic networks, such as USArray, lead to higher-resolution seismic images underneath continents. However, the imbalanced distribution of stations and sources poses challenges in global ray coverage. We adapt double-difference multitaper measurements to global adjoint tomography. We normalize each DD measurement by its number of pairs, and if a measurement has no pair, as may frequently happen for data recorded at oceanic stations, classical multitaper measurements are used. As a result, the differential measurements and pair-wise weighting strategy help balance uneven global kernel coverage. Our initial experiments with minor- and major-arc surface waves show promising results, revealing more pronounced structure near dense networks while reducing the prominence of paths towards cluster of stations. We have started using this new measurement in global adjoint inversions, addressing azimuthal anisotropy in upper mantle. Meanwhile, we are working on combining the double-difference approach with instantaneous phase measurements to emphasize contributions of scattered waves in global inversions and extending it to body waves. We will present our results and discuss challenges and future directions in the context of global tomographic inversions.

Faculty Sufficiency and AACSB Accreditation Compliance within a Global University: A Mathematical Modeling Approach

ERIC Educational Resources Information Center

Boronico, Jess; Murdy, Jim; Kong, Xinlu

2014-01-01

This manuscript proposes a mathematical model to address faculty sufficiency requirements towards assuring overall high quality management education at a global university. Constraining elements include full-time faculty coverage by discipline, location, and program, across multiple campus locations subject to stated service quality standards of…

Global Precipitation Measurement Poster

NASA Technical Reports Server (NTRS)

Azarbarzin, Art

2010-01-01

This poster presents an overview of the Global Precipitation Measurement (GPM) constellation of satellites which are designed to measure the Earth's precipitation. It includes the schedule of launches for the various satellites in the constellation, and the coverage of the constellation, It also reviews the mission capabilities, and the mission science objectives.

Beyond health aid: would an international equalization scheme for universal health coverage serve the international collective interest?

PubMed Central

2014-01-01

It has been argued that the international community is moving ‘beyond aid’. International co-financing in the international collective interest is expected to replace altruistically motivated foreign aid. The World Health Organization promotes ‘universal health coverage’ as the overarching health goal for the next phase of the Millennium Development Goals. In order to provide a basic level of health care coverage, at least some countries will need foreign aid for decades to come. If international co-financing of global public goods is replacing foreign aid, is universal health coverage a hopeless endeavor? Or would universal health coverage somehow serve the international collective interest? Using the Sustainable Development Solutions Network proposal to finance universal health coverage as a test case, we examined the hypothesis that national social policies face the threat of a ‘race to the bottom’ due to global economic integration and that this threat could be mitigated through international social protection policies that include international cross-subsidies – a kind of ‘equalization’ at the international level. The evidence for the race to the bottom theory is inconclusive. We seem to be witnessing a ‘convergence to the middle’. However, the ‘middle’ where ‘convergence’ of national social policies is likely to occur may not be high enough to keep income inequality in check. The implementation of the international equalization scheme proposed by the Sustainable Development Solutions Network would allow to ensure universal health coverage at a cost of US$55 in low income countries-the minimum cost estimated by the World Health Organization. The domestic efforts expected from low and middle countries are far more substantial than the international co-financing efforts expected from high income countries. This would contribute to ‘convergence’ of national social policies at a higher level. We therefore submit that the proposed international equalization scheme should not be considered as foreign aid, but rather as an international collective effort to protect and promote national social policy in times of global economic integration: thus serving the international collective interest. PMID:24886583

Survey of distribution of seasonal influenza vaccine doses in 201 countries (2004-2015): The 2003 World Health Assembly resolution on seasonal influenza vaccination coverage and the 2009 influenza pandemic have had very little impact on improving influenza control and pandemic preparedness.

PubMed

Palache, A; Abelin, A; Hollingsworth, R; Cracknell, W; Jacobs, C; Tsai, T; Barbosa, P

2017-08-24

There is no global monitoring system for influenza vaccination coverage, making it difficult to assess progress towards the 2003 World Health Assembly (WHA) vaccination coverage target. In 2008, the IFPMA Influenza Vaccine Supply International Task Force (IVS) developed a survey method to assess the global distribution of influenza vaccine doses as a proxy for vaccination coverage rates. The latest dose distribution data for 2014 and 2015 was used to update previous analyses. Data were confidentially collected and aggregated by the IFPMA Secretariat, and combined with previous IFPMA IVS survey data (2004-2013). Data were available from 201 countries over the 2004-2015 period. A "hurdle" rate was defined as the number of doses required to reach 15.9% of the population in 2008. Overall, the number of distributed doses progressively increased between 2004 and 2011, driven by a 150% increase in AMRO, then plateaued. One percent fewer doses were distributed in 2015 than in 2011. Twenty-three countries were above the hurdle rate in 2015, compared to 15 in 2004, but distribution was highly uneven in and across all WHO regions. Three WHO regions (AMRO, EURO and WPRO) accounted for about 95% of doses distributed. But in EURO and WPRO, distribution rates in 2015 were only marginally higher than in 2004, and in EURO there was an overall downward trend in dose distribution. The vast majority of countries cannot meet the 2003WHA coverage targets and are inadequately prepared for a global influenza pandemic. With only 5% of influenza vaccine doses being distributed to 50% of the world's population, there is urgency to redress the gross inequities in disease prevention and in pandemic preparedness. The 2003WHA resolution must be reviewed and revised and a call issued for the renewed commitment of Member States to influenza vaccination coverage targets. Copyright © 2017. Published by Elsevier Ltd.

The development and validation of command schedules for SeaWiFS

NASA Astrophysics Data System (ADS)

Woodward, Robert H.; Gregg, Watson W.; Patt, Frederick S.

1994-11-01

An automated method for developing and assessing spacecraft and instrument command schedules is presented for the Sea-viewing Wide Field-of-view Sensor (SeaWiFS) project. SeaWiFS is to be carried on the polar-orbiting SeaStar satellite in 1995. The primary goal of the SeaWiFS mission is to provide global ocean chlorophyll concentrations every four days by employing onboard recorders and a twice-a-day data downlink schedule. Global Area Coverage (GAC) data with about 4.5 km resolution will be used to produce the global coverage. Higher resolution (1.1 km resolution) Local Area Coverage (LAC) data will also be recorded to calibrate the sensor. In addition, LAC will be continuously transmitted from the satellite and received by High Resolution Picture Transmission (HRPT) stations. The methods used to generate commands for SeaWiFS employ numerous hierarchical checks as a means of maximizing coverage of the Earth's surface and fulfilling the LAC data requirements. The software code is modularized and written in Fortran with constructs to mirror the pre-defined mission rules. The overall method is specifically developed for low orbit Earth-observing satellites with finite onboard recording capabilities and regularly scheduled data downlinks. Two software packages using the Interactive Data Language (IDL) for graphically displaying and verifying the resultant command decisions are presented. Displays can be generated which show portions of the Earth viewed by the sensor and spacecraft sub-orbital locations during onboard calibration activities. An IDL-based interactive method of selecting and testing LAC targets and calibration activities for command generation is also discussed.

Modeling the Global Coronal Field with Simulated Synoptic Magnetograms from Earth and the Lagrange Points L3, L4, and L5

NASA Astrophysics Data System (ADS)

Petrie, Gordon; Pevtsov, Alexei; Schwarz, Andrew; DeRosa, Marc

2018-06-01

The solar photospheric magnetic flux distribution is key to structuring the global solar corona and heliosphere. Regular full-disk photospheric magnetogram data are therefore essential to our ability to model and forecast heliospheric phenomena such as space weather. However, our spatio-temporal coverage of the photospheric field is currently limited by our single vantage point at/near Earth. In particular, the polar fields play a leading role in structuring the large-scale corona and heliosphere, but each pole is unobservable for {>} 6 months per year. Here we model the possible effect of full-disk magnetogram data from the Lagrange points L4 and L5, each extending longitude coverage by 60°. Adding data also from the more distant point L3 extends the longitudinal coverage much further. The additional vantage points also improve the visibility of the globally influential polar fields. Using a flux-transport model for the solar photospheric field, we model full-disk observations from Earth/L1, L3, L4, and L5 over a solar cycle, construct synoptic maps using a novel weighting scheme adapted for merging magnetogram data from multiple viewpoints, and compute potential-field models for the global coronal field. Each additional viewpoint brings the maps and models into closer agreement with the reference field from the flux-transport simulation, with particular improvement at polar latitudes, the main source of the fast solar wind.

The Global Precipitation Climatology Project: First Algorithm Intercomparison Project

NASA Technical Reports Server (NTRS)

Arkin, Phillip A.; Xie, Pingping

1994-01-01

The Global Precipitation Climatology Project (GPCP) was established by the World Climate Research Program to produce global analyses of the area- and time-averaged precipitation for use in climate research. To achieve the required spatial coverage, the GPCP uses simple rainfall estimates derived from IR and microwave satellite observations. In this paper, we describe the GPCP and its first Algorithm Intercomparison Project (AIP/1), which compared a variety of rainfall estimates derived from Geostationary Meteorological Satellite visible and IR observations and Special Sensor Microwave/Imager (SSM/I) microwave observations with rainfall derived from a combination of radar and raingage data over the Japanese islands and the adjacent ocean regions during the June and mid-July through mid-August periods of 1989. To investigate potential improvements in the use of satellite IR data for the estimation of large-scale rainfall for the GPCP, the relationship between rainfall and the fractional coverage of cold clouds in the AIP/1 dataset is examined. Linear regressions between fractional coverage and rainfall are analyzed for a number of latitude-longitude areas and for a range of averaging times. The results show distinct differences in the character of the relationship for different portions of the area. These results suggest that the simple IR-based estimation technique currently used in the GPCP can be used to estimate rainfall for global tropical and subtropical areas, provided that a method for adjusting the proportional coefficient for varying areas and seasons can be determined.

[Responses of plant community structure and species composition to warming and N addition in an alpine meadow, northern Tibetan Plateau, China].

PubMed

Zong, Ning; Chai, Xi; Shi, Pei Li; Jiang, Jing; Niu, Ben; Zhang, Xian Zhou; He, Yong Tao

2016-12-01

Global climate warming and increasing nitrogen (N) deposition, as controversial global environmental issues, may distinctly affect the functions and processes of terrestrial ecosystems. It has been reported that the Qinghai-Tibet Plateau has been experiencing significant warming in recent decades, especially in winter. Previous studies have mainly focused on the effects of warming all the year round; however, few studies have tested the effects of winter warming. To investigate the effects of winter warming and N addition on plant community structure and species composition of alpine meadow, long-term N addition and simulated warming experiment was conducted in alpine meadow from 2010 in Damxung, northern Tibet. The experiment consisted of three warming patterns: Year-round warming (YW), winter warming (WW) and control (NW), crossed respectively with five N gradients: 0, 10, 20, 40, 80 kg N·hm -2 ·a -1 . From 2012 to 2014, both warming and N addition significantly affected the total coverage of plant community. Specifically, YW significantly decreased the total coverage of plant community. Without N addition, WW remarkably reduced the vegetation coverage. However, with N addition, the total vegetation coverage gradually increased with the increase of N level. Warming and N addition had different effects on plants from different functional groups. Warming significantly reduced the plant coverage of grasses and sedges, while N addition significantly enhanced the plant coverage of grasses. Regression analyses showed that the total coverage of plant community was positively related to soil water content in vigorous growth stages, indicating that the decrease in soil water content resulted from warming during dry seasons might be the main reason for the decline of total community coverage. As soil moisture in semi-arid alpine meadow is mainly regulated by rainfalls, our results indicated that changes in spatial and temporal patterns of rainfalls under the future climate change scenarios would dramatically influence the vegetation coverage and species composition. Additionally, the effects of increasing atmospheric N deposition on vegetation community might also depend on the change of rainfall patterns.

Aligning US health and immigration policy to reduce the incidence of tuberculosis.

PubMed

Blewett, L A; Marmor, S; Pintor, J K; Boudreaux, M

2014-04-01

Tuberculosis (TB) is a significant public health issue, claiming 1.4 million lives worldwide in 2011. Using data from the 2009-2010 National Health Interview Survey, we examine variation in 'having heard of TB' (HTB) by global region of birth and health insurance status. Cross-sectional analysis with bivariate comparisons and multivariate logistic regression to evaluate how adults differed in reported HTB, controlling for global region of birth. HTB rates ranged from 63.4% of adults born in Asia to 88.6% born in Europe. Uninsured immigrants had the lowest rate of HTB, ranging from a low of 50.1% of uninsured adults born in Asia to 77.6% born in Europe and 90.8% of US-born uninsured adults. Longer length of time in the United States (>5 years) was significantly associated with increased likelihood of HTB, as did being of Asian race/ethnicity and being male. Those with private health insurance coverage had the highest rates of HTB. To reduce persistent TB, public health program directors and policy makers must 1) recognize the variation in HTB by global region of birth and prioritize areas with the lowest HTB rates, and 2) reduce barriers to health insurance coverage by eliminating the 5-year ban for public program coverage for new immigrants.

Landsat Data Continuity Mission

USGS Publications Warehouse

,

2007-01-01

The Landsat Data Continuity Mission (LDCM) is a partnership between the National Aeronautics and Space Administration (NASA) and the U.S. Geological Survey (USGS) to place the next Landsat satellite in orbit by late 2012. The Landsat era that began in 1972 will become a nearly 45-year global land record with the successful launch and operation of the LDCM. The LDCM will continue the acquisition, archival, and distribution of multispectral imagery affording global, synoptic, and repetitive coverage of the Earth's land surfaces at a scale where natural and human-induced changes can be detected, differentiated, characterized, and monitored over time. The mission objectives of the LDCM are to (1) collect and archive medium resolution (circa 30-m spatial resolution) multispectral image data affording seasonal coverage of the global landmasses for a period of no less than 5 years; (2) ensure that LDCM data are sufficiently consistent with data from the earlier Landsat missions, in terms of acquisition geometry, calibration, coverage characteristics, spectral characteristics, output product quality, and data availability to permit studies of land-cover and land-use change over time; and (3) distribute LDCM data products to the general public on a nondiscriminatory basis and at a price no greater than the incremental cost of fulfilling a user request. Distribution of LDCM data over the Internet at no cost to the user is currently planned.

Sharing Data in the Global Ocean Observing System (Invited)

NASA Astrophysics Data System (ADS)

Lindstrom, E. J.; McCurdy, A.; Young, J.; Fischer, A. S.

2010-12-01

We examine the evolution of data sharing in the field of physical oceanography to highlight the challenges now before us. Synoptic global observation of the ocean from space and in situ platforms has significantly matured over the last two decades. In the early 1990’s the community data sharing challenges facing the World Ocean Circulation Experiment (WOCE) largely focused on the behavior of individual scientists. Satellite data sharing depended on the policy of individual agencies. Global data sets were delivered with considerable delay and with enormous personal sacrifice. In the 2000’s the requirements for global data sets and sustained observations from the likes of the U.N. Framework Convention on Climate Change have led to data sharing and cooperation at a grander level. It is more effective and certainly more efficient. The Joint WMO/IOC Technical Commission on Oceanography and Marine Meteorology (JCOMM) provided the means to organize many aspects of data collection and data dissemination globally, for the common good. In response the Committee on Earth Observing Satellites organized Virtual Constellations to enable the assembly and sharing of like kinds of satellite data (e.g., sea surface topography, ocean vector winds, and ocean color). Individuals in physical oceanography have largely adapted to the new rigors of sharing data for the common good, and as a result of this revolution new science has been enabled. Primary obstacles to sharing have shifted from the individual level to the national level. As we enter into the 2010’s the demands for ocean data continue to evolve with an expanded requirement for more real-time reporting and broader disciplinary coverage, to answer key scientific and societal questions. We are also seeing the development of more numerous national contributions to the global observing system. The drivers for the establishment of global ocean observing systems are expanding beyond climate to include biological and biogeochemical issues (e.g. biodiversity and ecosystem services, fisheries collapse, and ocean acidification). This expanded suite of demands and drivers challenge us further to share data for the common good across specialties. This requires that more ocean scientific communities and national ocean observing programs move towards maturity in terms of global data collection capability, sharing capacity, and data management standards. In oceanography the time has arrived for a cultural shift toward more shared collective observing capabilities. Necessarily we must also rapidly move toward harmony in national data sharing policies for the ocean environment. Building capacity to share ocean observations has been an objective for decades and has resulted in an expanded understanding of technologies and management policies that foster data sharing and provenance tracking.

Malaria vector control at a crossroads: public health entomology and the drive to elimination.

PubMed

Mnzava, Abraham P; Macdonald, Michael B; Knox, Tessa B; Temu, Emmanuel A; Shiff, Clive J

2014-09-01

Vector control has been at the core of successful malaria control. However, a dearth of field-oriented vector biologists threatens to undermine global reductions in malaria burden. Skilled cadres are needed to manage insecticide resistance, to maintain coverage with current interventions, to develop new paradigms for tackling 'residual' transmission and to target interventions as transmission becomes increasingly heterogeneous. Recognising this human resource crisis, in September 2013, WHO Global Malaria Programme issued guidance for capacity building in entomology and vector control, including recommendations for countries and implementing partners. Ministries were urged to develop long-range strategic plans for building human resources for public health entomology and vector control (including skills in epidemiology, geographic information systems, operational research and programme management) and to set in place the requisite professional posts and career opportunities. Capacity building and national ownership in all partner projects and a clear exit strategy to sustain human and technical resources after project completion were emphasised. Implementing partners were urged to support global and regional efforts to enhance public health entomology capacity. While the challenges inherent in such capacity building are great, so too are the opportunities to establish the next generation of public health entomologists that will enable programmes to continue on the path to malaria elimination. © The Author 2014. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Global Monitoring of Air Pollution Using Spaceborne Sensors

NASA Technical Reports Server (NTRS)

Chu, D. A.; Kaufman, Y. J.; Tanre, D.; Remer, L. A.; Einaudi, Franco (Technical Monitor)

2000-01-01

The MODIS sensor onboard EOS-Terra satellite provides not only daily global coverage but also high spectral (36 channels from 0.41 to 14 microns wavelength) and spatial (250m, 500m and 1km) resolution measurements. A similar MODIS instrument will be also configured into EOS-Aqua satellite to be launched soon. Using the complementary EOS-Terra and EOS-Aqua sun-synchronous orbits (10:30 AM and 1:30 PM equator-crossing time respectively), it enables us also to study the diurnal changes of the Earth system. It is unprecedented for the derivation of aerosol properties with such high spatial resolution and daily global converge. Aerosol optical depth and other aerosol properties, e.g., Angstrom coefficient over land and particle size over ocean, are derived as standard products at a spatial resolution of 10 x 10 sq km. The high resolution results are found surprisingly useful in detecting aerosols in both urban and rural regions as a result of urban/industrial pollution and biomass burning. For long-lived aerosols, the ability to monitoring the evolution of these aerosol events could help us to establish an system of air quality especially for highly populated areas. Aerosol scenarios with city pollution and biomass burning will be presented. Also presented are the method used in the derivation of aerosol optical properties and preliminary results will be presented, and issue as well as obstacles in validating aerosol optical depth with AERONET ground-based observations.

New Multispectral Cloud Retrievals from MODIS

NASA Technical Reports Server (NTRS)

Platnick, Steven; Tsay, Si-Chee; Ackerman, Steven A.; Gray, Mark A.; Moody, Eric G.; Li, Jason Y.; Arnold, G. T.; King, Michael D. (Technical Monitor)

2000-01-01

The Moderate Resolution Imaging Spectroradiometer (MODIS) was developed by NASA and launched onboard the Terra spacecraft on December 18, 1999. It achieved its final orbit and began Earth observations on February 24, 2000. MODIS scans a swath width sufficient to provide nearly complete global coverage every two days from a polar-orbiting, sun-synchronous, platform at an altitude of 705 km, and provides images in 36 spectral bands between 0.415 and 14.235 micrometers with spatial resolutions of 250 m (2 bands), 500 m (5 bands) and 1000 m (29 bands). These bands have been carefully selected to enable advanced studies of land, ocean, and atmospheric processes. In this paper I will describe the various methods being used for the remote sensing of cloud properties using MODIS data, focusing primarily on the MODIS cloud mask used to distinguish clouds, clear sky, heavy aerosol, and shadows on the ground, and on the remote sensing of cloud optical properties, especially cloud optical thickness and effective radius of cloud drops and ice crystals. Results will be presented of MODIS cloud properties both over the land and over the ocean, showing the consistency in cloud retrievals over various ecosystems used in the retrievals. The implications of this new observing system on global analysis of the Earth's environment will be discussed.

Molecular diagnostics using magnetic nanobeads

NASA Astrophysics Data System (ADS)

Zardán Gómez de la Torre, Teresa; Strömberg, Mattias; Göransson, Jenny; Gunnarsson, Klas; Nilsson, Mats; Svedlindh, Peter; Strømme, Maria

2010-01-01

In this paper, we investigate the volume-amplified magnetic nanobead detection assay with respect to bead size, bead concentration and bead oligonucleotide surface coverage in order to improve the understanding of the underlying microscopic mechanisms. It has been shown that: (i) the immobilization efficiency of the beads depends on the surface coverage of oligonucleotides, (ii) by using lower amounts of probe-tagged beads, detection sensitivity can be improved and (iii) using small enough beads enables both turn-off and turn-on detection. Finally, biplex detection was demonstrated.

Understanding the impact of global trade liberalization on health systems pursuing universal health coverage.

PubMed

Missoni, Eduardo

2013-01-01

In the context of reemerging universalistic approaches to health care, the objective of this article was to contribute to the discussion by highlighting the potential influence of global trade liberalization on the balance between health demand and the capacity of health systems pursuing universal health coverage (UHC) to supply adequate health care. Being identified as a defining feature of globalization affecting health, trade liberalization is analyzed as a complex and multidimensional influence on the implementation of UHC. The analysis adopts a systems-thinking approach and refers to the six building blocks of World Health Organization's current "framework for action," emphasizing their interconnectedness. While offering new opportunities to increase access to health information and care, in the absence of global governance mechanisms ensuring adequate health protection and promotion, global trade tends to have negative effects on health systems' capacity to ensure UHC, both by causing higher demand and by interfering with the interconnected functioning of health systems' building blocks. The prevention of such an impact and the effective implementation of UHC would highly benefit from a more consistent commitment and stronger leadership by the World Health Organization in protecting health in global policymaking fora in all sectors. Copyright © 2013 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

Spatial assessment of land degradation through key ecosystem services: The role of globally available data.

PubMed

Cerretelli, Stefania; Poggio, Laura; Gimona, Alessandro; Yakob, Getahun; Boke, Shiferaw; Habte, Mulugeta; Coull, Malcolm; Peressotti, Alessandro; Black, Helaina

2018-07-01

Land degradation is a serious issue especially in dry and developing countries leading to ecosystem services (ESS) degradation due to soil functions' depletion. Reliably mapping land degradation spatial distribution is therefore important for policy decisions. The main objectives of this paper were to infer land degradation through ESS assessment and compare the modelling results obtained using different sets of data. We modelled important physical processes (sediment erosion and nutrient export) and the equivalent ecosystem services (sediment and nutrient retention) to infer land degradation in an area in the Ethiopian Great Rift Valley. To model soil erosion/retention capability, and nitrogen export/retention capability, two datasets were used: a 'global' dataset derived from existing global-coverage data and a hybrid dataset where global data were integrated with data from local surveys. The results showed that ESS assessments can be used to infer land degradation and identify priority areas for interventions. The comparison between the modelling results of the two different input datasets showed that caution is necessary if only global-coverage data are used at a local scale. In remote and data-poor areas, an approach that integrates global data with targeted local sampling campaigns might be a good compromise to use ecosystem services in decision-making. Copyright © 2018. Published by Elsevier B.V.

Towards Semantic Web Services on Large, Multi-Dimensional Coverages

NASA Astrophysics Data System (ADS)

Baumann, P.

2009-04-01

Observed and simulated data in the Earth Sciences often come as coverages, the general term for space-time varying phenomena as set forth by standardization bodies like the Open GeoSpatial Consortium (OGC) and ISO. Among such data are 1-d time series, 2-D surface data, 3-D surface data time series as well as x/y/z geophysical and oceanographic data, and 4-D metocean simulation results. With increasing dimensionality the data sizes grow exponentially, up to Petabyte object sizes. Open standards for exploiting coverage archives over the Web are available to a varying extent. The OGC Web Coverage Service (WCS) standard defines basic extraction operations: spatio-temporal and band subsetting, scaling, reprojection, and data format encoding of the result - a simple interoperable interface for coverage access. More processing functionality is available with products like Matlab, Grid-type interfaces, and the OGC Web Processing Service (WPS). However, these often lack properties known as advantageous from databases: declarativeness (describe results rather than the algorithms), safe in evaluation (no request can keep a server busy infinitely), and optimizable (enable the server to rearrange the request so as to produce the same result faster). WPS defines a geo-enabled SOAP interface for remote procedure calls. This allows to webify any program, but does not allow for semantic interoperability: a function is identified only by its function name and parameters while the semantics is encoded in the (only human readable) title and abstract. Hence, another desirable property is missing, namely an explicit semantics which allows for machine-machine communication and reasoning a la Semantic Web. The OGC Web Coverage Processing Service (WCPS) language, which has been adopted as an international standard by OGC in December 2008, defines a flexible interface for the navigation, extraction, and ad-hoc analysis of large, multi-dimensional raster coverages. It is abstract in that it does not anticipate any particular protocol. One such protocol is given by the OGC Web Coverage Service (WCS) Processing Extension standard which ties WCPS into WCS. Another protocol which makes WCPS an OGC Web Processing Service (WPS) Profile is under preparation. Thereby, WCPS bridges WCS and WPS. The conceptual model of WCPS relies on the coverage model of WCS, which in turn is based on ISO 19123. WCS currently addresses raster-type coverages where a coverage is seen as a function mapping points from a spatio-temporal extent (its domain) into values of some cell type (its range). A retrievable coverage has an identifier associated, further the CRSs supported and, for each range field (aka band, channel), the interpolation methods applicable. The WCPS language offers access to one or several such coverages via a functional, side-effect free language. The following example, which derives the NDVI (Normalized Difference Vegetation Index) from given coverages C1, C2, and C3 within the regions identified by the binary mask R, illustrates the language concept: for c in ( C1, C2, C3 ), r in ( R ) return encode( (char) (c.nir - c.red) / (c.nir + c.red), H˜DF-EOS\\~ ) The result is a list of three HDF-EOS encoded images containing masked NDVI values. Note that the same request can operate on coverages of any dimensionality. The expressive power of WCPS includes statistics, image, and signal processing up to recursion, to maintain safe evaluation. As both syntax and semantics of any WCPS expression is well known the language is Semantic Web ready: clients can construct WCPS requests on the fly, servers can optimize such requests (this has been investigated extensively with the rasdaman raster database system) and automatically distribute them for processing in a WCPS-enabled computing cloud. The WCPS Reference Implementation is being finalized now that the standard is stable; it will be released in open source once ready. Among the future tasks is to extend WCPS to general meshes, in synchronization with the WCS standard. In this talk WCPS is presented in the context of OGC standardization. The author is co-chair of OGC's WCS Working Group (WG) and Coverages WG.

AIRTV: Broadband Direct to Aircraft

NASA Astrophysics Data System (ADS)

Sorbello, R.; Stone, R.; Bennett, S. B.; Bertenyi, E.

2002-01-01

Airlines have been continuously upgrading their wide-body, long-haul aircraft with IFE (in-flight entertainment) systems that can support from 12 to 24 channels of video entertainment as well as provide the infrastructure to enable in-seat delivery of email and internet services. This is a direct consequence of increased passenger demands for improved in-flight services along with the expectations that broadband delivery systems capable of providing live entertainment (news, sports, financial information, etc.) and high speed data delivery will soon be available. The recent events of Sept. 11 have slowed the airline's upgrade of their IFE systems, but have also highlighted the compelling need for broadband aeronautical delivery systems to include operational and safety information. Despite the impact of these events, it is estimated that by 2005 more than 3000 long haul aircraft (servicing approximately 1 billion passengers annually) will be fully equipped with modern IFE systems. Current aircraft data delivery systems, which use either Inmarsat or NATS, are lacking in bandwidth and consequently are unsuitable to satisfy passenger demands for broadband email/internet services or the airlines' burgeoning data requirements. Present live video delivery services are limited to regional coverage and are not readily expandable to global or multiregional service. Faced with a compelling market demand for high data transport to aircraft, AirTV has been developing a broadband delivery system that will meet both passengers' and airlines' needs. AirTV is a global content delivery system designed to provide a range of video programming and data services to commercial airlines. When AirTV is operational in 2004, it will provide a broadband connection directly to the aircraft, delivering live video entertainment, internet/email service and essential operational and safety data. The system has been designed to provide seamless global service to all airline routes except for those over the poles. The system consists of a constellation of 4 geostationary satellites covering the earth and delivering its signals to the aircraft at S band (2.52 -2.67 GHz). The S-band spectrum is ideal for this application since it is allocated on a primary basis by the ITU for global broadcast service. The AirTV service is expected to begin in 2004 and should be unencumbered by adjacent satellite interference due to near completion of the ITU coordination process. Each satellite will deliver four 20 Mbps QPSK data streams consisting of multiplexed compressed digital video channels and IP data over the full global beam coverage. The 80 Mbps capacity of each satellite will provide approximately 60 video channels while still allocating 40 Mbits to data services. The combined constellation capacity of 320 Mbits will significantly exceed the capacity of any similar existing or currently planned global satellite system. In addition, the simplicity of the 4-satellite approach is the most cost effective means to deliver high bandwidth globally. Return links, which are required for internet service, will be provided through the existing Inmarsat Aero-H system already onboard virtually all long haul aircraft and will provide return data rates from the aircraft as high as 432 kbps. integrated receiver/decoder (IRD) assembly. The phased array antenna, a key technology element, is being developed by AirTV's strategic partner, CMC Electronics. This antenna is a scaled version of CMC's Inmarsat Aero H antenna and is capable of scanning to 5 degrees above the horizon. Wide angle scanning up to 85 degrees from zenith is necessary for aircraft traversing the northernmost latitudes on transoceanic routes. AirTV has designed both the satellite coverage and aircraft antenna performance to ensure that high signal quality is maintained along all non-polar airline routes. AirTV will be the future of aeronautical broadband delivery. It has been designed specifically for global services and uses the ideal spectrum for this application. It will revolutionize the delivery of content to aircraft. This paper will describe the AirTV system and highlight its advanced service capabilities.

The Role of Sea Ice in 2 x CO2 Climate Model Sensitivity. Part 2; Hemispheric Dependencies

NASA Technical Reports Server (NTRS)

Rind, D.; Healy, R.; Parkinson, C.; Martinson, D.

1997-01-01

How sensitive are doubled CO2 simulations to GCM control-run sea ice thickness and extent? This issue is examined in a series of 10 control-run simulations with different sea ice and corresponding doubled CO2 simulations. Results show that with increased control-run sea ice coverage in the Southern Hemisphere, temperature sensitivity with climate change is enhanced, while there is little effect on temperature sensitivity of (reasonable) variations in control-run sea ice thickness. In the Northern Hemisphere the situation is reversed: sea ice thickness is the key parameter, while (reasonable) variations in control-run sea ice coverage are of less importance. In both cases, the quantity of sea ice that can be removed in the warmer climate is the determining factor. Overall, the Southern Hemisphere sea ice coverage change had a larger impact on global temperature, because Northern Hemisphere sea ice was sufficiently thick to limit its response to doubled CO2, and sea ice changes generally occurred at higher latitudes, reducing the sea ice-albedo feedback. In both these experiments and earlier ones in which sea ice was not allowed to change, the model displayed a sensitivity of -0.02 C global warming per percent change in Southern Hemisphere sea ice coverage.

Combined Global Navigation Satellite Systems in the Space Service Volume

NASA Technical Reports Server (NTRS)

Force, Dale A.; Miller, James J.

2015-01-01

Besides providing position, navigation, and timing (PNT) services to traditional terrestrial and airborne users, GPS is also being increasingly used as a tool to enable precision orbit determination, precise time synchronization, real-time spacecraft navigation, and three-axis attitude control of Earth orbiting satellites. With additional Global Navigation Satellite System (GNSS) constellations being replenished and coming into service (GLONASS, Beidou, and Galileo), it will become possible to benefit from greater signal availability and robustness by using evolving multi-constellation receivers. The paper, "GPS in the Space Service Volume," presented at the ION GNSS 19th International Technical Meeting in 2006 (Ref. 1), defined the Space Service Volume, and analyzed the performance of GPS out to seventy thousand kilometers. This paper will report a similar analysis of the signal coverage of GPS in the space domain; however, the analyses will also consider signal coverage from each of the additional GNSS constellations noted earlier to specifically demonstrate the expected benefits to be derived from using GPS in conjunction with other foreign systems. The Space Service Volume is formally defined as the volume of space between three thousand kilometers altitude and geosynchronous altitude circa 36,000 km, as compared with the Terrestrial Service Volume between 3,000 km and the surface of the Earth. In the Terrestrial Service Volume, GNSS performance is the same as on or near the Earth's surface due to satellite vehicle availability and geometry similarities. The core GPS system has thereby established signal requirements for the Space Service Volume as part of technical Capability Development Documentation (CDD) that specifies system performance. Besides the technical discussion, we also present diplomatic efforts to extend the GPS Space Service Volume concept to other PNT service providers in an effort to assure that all space users will benefit from the enhanced interoperability of GNSS services in the space domain. A separate paper presented at the conference covers the individual GNSS performance parameters for respective Space Service Volumes.

Bhutan's National ECCD Impact Evaluation: Local, National, and Global Perspectives

ERIC Educational Resources Information Center

Pisani, Lauren; Dyenka, Karma; Sharma, Parvati; Chhetri, Nar; Dang, Sara; Gayleg, Karma; Wangdi, Chencho

2017-01-01

Early childhood care and development (ECCD) services have been steadily expanding with structures on the community, national, and international levels. However, many low- and middle-income countries still have very limited ECCD coverage, and there is a lack of global guidance on best practices for effectively expanding pre-primary education. In…

Measuring the extent and effectiveness of protected areas as an indicator for meeting global biodiversity targets

PubMed Central

Chape, S; Harrison, J; Spalding, M; Lysenko, I

2005-01-01

There are now over 100 000 protected areas worldwide, covering over 12% of the Earth's land surface. These areas represent one of the most significant human resource use allocations on the planet. The importance of protected areas is reflected in their widely accepted role as an indicator for global targets and environmental assessments. However, measuring the number and extent of protected areas only provides a unidimensional indicator of political commitment to biodiversity conservation. Data on the geographic location and spatial extent of protected areas will not provide information on a key determinant for meeting global biodiversity targets: ‘effectiveness’ in conserving biodiversity. Although tools are being devised to assess management effectiveness, there is no globally accepted metric. Nevertheless, the numerical, spatial and geographic attributes of protected areas can be further enhanced by investigation of the biodiversity coverage of these protected areas, using species, habitats or biogeographic classifications. This paper reviews the current global extent of protected areas in terms of geopolitical and habitat coverage, and considers their value as a global indicator of conservation action or response. The paper discusses the role of the World Database on Protected Areas and collection and quality control issues, and identifies areas for improvement, including how conservation effectiveness indicators may be included in the database to improve the value of protected areas data as an indicator for meeting global biodiversity targets. PMID:15814356

MAVEN Mapping of Plasma Clouds Near Mars

NASA Astrophysics Data System (ADS)

Hurley, D.; Tran, T.; DiBraccio, G. A.; Espley, J. R.; Soobiah, Y. I. J.

2017-12-01

Brace et al. identified parcels of ionospheric plasma above the nominal ionosphere of Venus, dubbed plasma clouds. These were envisioned as instabilities on the ionopause that evolved to escaping parcels of ionospheric plasma. Mars Global Surveyor (MGS) Electron Reflectometer (ER) also detected signatures of ionospheric plasma above the nominal ionopause of Mars. Initial examination of the MGS ER data suggests that plasma clouds are more prevalent at Mars than at Venus, and similarly exhibit a connection to rotations in the upstream Interplanetary Magnetic Field (IMF) as Zhang et al. showed at Venus. We examine electron data from Mars to determine the locations of plasma clouds in the near-Mars environment using MGS and MAVEN data. The extensive coverage of the MAVEN orbit enables mapping an occurrence rate of the photoelectron spectra in Solar Wind Electron Analyzer (SWEA) data spanning all relevant altitudes and solar zenith angles. Martian plasma clouds are observed near the terminator like at Venus. They move to higher altitude as solar zenith angle increases, consistent with the escaping plasma hypothesis.

InSAR imaging of volcanic deformation over cloud-prone areas - Aleutian islands

USGS Publications Warehouse

Lu, Zhong

2007-01-01

Interferometric synthetic aperture radar (INSAR) is capable of measuring ground-surface deformation with centimeter-tosubcentimeter precision and spatial resolution of tens-of meters over a relatively large region. With its global coverage and all-weather imaging capability, INSAR is an important technique for measuring ground-surface deformation of volcanoes over cloud-prone and rainy regions such as the Aleutian Islands, where only less than 5 percent of optical imagery is usable due to inclement weather conditions. The spatial distribution of surface deformation data, derived from INSAR images, enables the construction of detailed mechanical models to enhance the study of magmatic processes. This paper reviews the basics of INSAR for volcanic deformation mapping and the INSAR studies of ten Aleutian volcanoes associated with both eruptive and noneruptive activity. These studies demonstrate that all-weather INSAR imaging can improve our understanding of how the Aleutian volcanoes work and enhance our capability to predict future eruptions and associated hazards.

Plant iTRAQ-based proteomics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Handakumbura, Pubudu; Hixson, Kim K.; Purvine, Samuel O.

We present a simple one-­pot extraction protocol, which rapidly isolates hydrophyllic metabolites, lipids, and proteins from the same pulverized plant sample. Also detailed is a global plant proteomics sample preparation method utilizing iTRAQ multiplexing reagents that enables deep proteome coverage due to the use of HPLC fractionation of the peptides prior to mass spectrometric analysis. We have successfully used this protocol on several different plant tissues (e.g., roots, stems, leaves) from different plants (e.g., sorghum, poplar, Arabidopsis, soybean), and have been able to successfully detect and quantify thousands of proteins. Multiplexing strategies such as iTRAQ and the bioinformatics strategy outlinedmore » here, ultimately provide insight into which proteins are significantly changed in abundance between two or more groups (e.g., control, perturbation). Our bioinformatics strategy yields z-­score values, which normalize the expression data into a format that can easily be cross-­compared with other expression data (i.e., metabolomics, transcriptomics) obtained from different analytical methods and instrumentation.« less

Advanced Spectroscopic and Thermal Imaging Instrumentation for Shock Tube and Ballistic Range Facilities

NASA Technical Reports Server (NTRS)

Grinstead, Jay H.; Wilder, Michael C.; Reda, Daniel C.; Cruden, Brett A.; Bogdanoff, David W.

2010-01-01

The Electric Arc Shock Tube (EAST) facility and Hypervelocity Free Flight Aerodynamic Facility (HFFAF, an aeroballistic range) at NASA Ames support basic research in aerothermodynamic phenomena of atmospheric entry, specifically shock layer radiation spectroscopy, convective and radiative heat transfer, and transition to turbulence. Innovative optical instrumentation has been developed and implemented to meet the challenges posed from obtaining such data in these impulse facilities. Spatially and spectrally resolved measurements of absolute radiance of a travelling shock wave in EAST are acquired using multiplexed, time-gated imaging spectrographs. Nearly complete spectral coverage from the vacuum ultraviolet to the near infrared is possible in a single experiment. Time-gated thermal imaging of ballistic range models in flight enables quantitative, global measurements of surface temperature. These images can be interpreted to determine convective heat transfer rates and reveal transition to turbulence due to isolated and distributed surface roughness at hypersonic velocities. The focus of this paper is a detailed description of the optical instrumentation currently in use in the EAST and HFFAF.

Sensor Webs: Autonomous Rapid Response to Monitor Transient Science Events

NASA Technical Reports Server (NTRS)

Mandl, Dan; Grosvenor, Sandra; Frye, Stu; Sherwood, Robert; Chien, Steve; Davies, Ashley; Cichy, Ben; Ingram, Mary Ann; Langley, John; Miranda, Felix

2005-01-01

To better understand how physical phenomena, such as volcanic eruptions, evolve over time, multiple sensor observations over the duration of the event are required. Using sensor web approaches that integrate original detections by in-situ sensors and global-coverage, lower-resolution, on-orbit assets with automated rapid response observations from high resolution sensors, more observations of significant events can be made with increased temporal, spatial, and spectral resolution. This paper describes experiments using Earth Observing 1 (EO-1) along with other space and ground assets to implement progressive mission autonomy to identify, locate and image with high resolution instruments phenomena such as wildfires, volcanoes, floods and ice breakup. The software that plans, schedules and controls the various satellite assets are used to form ad hoc constellations which enable collaborative autonomous image collections triggered by transient phenomena. This software is both flight and ground based and works in concert to run all of the required assets cohesively and includes software that is model-based, artificial intelligence software.

Influence of ENSO on coastal flood hazard and exposure at the global-scale

NASA Astrophysics Data System (ADS)

Muis, S.; Haigh, I. D.; Guimarães Nobre, G.; Aerts, J.; Ward, P.

2017-12-01

The El Niño-Southern Oscillation (ENSO) is the dominant signal of interannual climate variability. The unusually warm (El Niño) and cold (La Niña) oceanic and atmospheric conditions in the tropical Pacific drives interannual variability in both mean and extreme sea levels, which in turn may influence the probabilities and impacts of coastal flooding. We assess the influence of ENSO on coastal flood hazard and exposure using daily timeseries from the Global Time and Surge Reanalysis (GTSR) dataset (Muis et al., 2016). As the GTSR timeseries do not include steric effects (i.e. density differences), we improve the GTSR timeseries by adding steric sea levels. Evaluation against observed sea levels shows that the including steric sea levels leads to a much better representation of the seasonal and interannual variability. We show that sea level anomalies occur during ENSO years with higher sea levels during La Niña in the South-Atlantic, Indian Ocean and the West Pacific, whereas sea levels are lower in the east Pacific. The pattern is generally inversed for El Niño. We also find an effect of ENSO in the number of people exposed to coastal flooding. Although the effect is minor at the global-scale, it may be important for flood risk management to consider at the national or sub national levels. Previous studies at the global-scale have used tide gauge observation to assess the influence of ENSO on extreme sea levels. The advantage of our approach over observations is that GTSR provides a consistent dataset with a full global coverage for the period 1979-2014. This allows us to assess ENSO's influence on sea level extremes anywhere in the world. Furthermore, it enables us to also calculate the impacts of extreme sea levels in terms of coastal flooding and exposed population. ReferencesMuis et al (2016) A global reanalysis of storm surges and extreme sea levels. Nature Communications.7:11969. doi:10.1038/ncomms11969.

Agile deployment and code coverage testing metrics of the boot software on-board Solar Orbiter's Energetic Particle Detector

NASA Astrophysics Data System (ADS)

Parra, Pablo; da Silva, Antonio; Polo, Óscar R.; Sánchez, Sebastián

2018-02-01

In this day and age, successful embedded critical software needs agile and continuous development and testing procedures. This paper presents the overall testing and code coverage metrics obtained during the unit testing procedure carried out to verify the correctness of the boot software that will run in the Instrument Control Unit (ICU) of the Energetic Particle Detector (EPD) on-board Solar Orbiter. The ICU boot software is a critical part of the project so its verification should be addressed at an early development stage, so any test case missed in this process may affect the quality of the overall on-board software. According to the European Cooperation for Space Standardization ESA standards, testing this kind of critical software must cover 100% of the source code statement and decision paths. This leads to the complete testing of fault tolerance and recovery mechanisms that have to resolve every possible memory corruption or communication error brought about by the space environment. The introduced procedure enables fault injection from the beginning of the development process and enables to fulfill the exigent code coverage demands on the boot software.

Assimilation of global versus local data sets into a regional model of the Gulf Stream system. 1. Data effectiveness

NASA Astrophysics Data System (ADS)

Malanotte-Rizzoli, Paola; Young, Roberta E.

1995-12-01

The primary objective of this paper is to assess the relative effectiveness of data sets with different space coverage and time resolution when they are assimilated into an ocean circulation model. We focus on obtaining realistic numerical simulations of the Gulf Stream system typically of the order of 3-month duration by constructing a "synthetic" ocean simultaneously consistent with the model dynamics and the observations. The model used is the Semispectral Primitive Equation Model. The data sets are the "global" Optimal Thermal Interpolation Scheme (OTIS) 3 of the Fleet Numerical Oceanography Center providing temperature and salinity fields with global coverage and with bi-weekly frequency, and the localized measurements, mostly of current velocities, from the central and eastern array moorings of the Synoptic Ocean Prediction (SYNOP) program, with daily frequency but with a very small spatial coverage. We use a suboptimal assimilation technique ("nudging"). Even though this technique has already been used in idealized data assimilation studies, to our knowledge this is the first study in which the effectiveness of nudging is tested by assimilating real observations of the interior temperature and salinity fields. This is also the first work in which a systematic assimilation is carried out of the localized, high-quality SYNOP data sets in numerical experiments longer than 1-2 weeks, that is, not aimed to forecasting. We assimilate (1) the global OTIS 3 alone, (2) the local SYNOP observations alone, and (3) both OTIS 3 and SYNOP observations. We assess the success of the assimilations with quantitative measures of performance, both on the global and local scale. The results can be summarized as follows. The intermittent assimilation of the global OTIS 3 is necessary to keep the model "on track" over 3-month simulations on the global scale. As OTIS 3 is assimilated at every model grid point, a "gentle" weight must be prescribed to it so as not to overconstrain the model. However, in these assimilations the predicted velocity fields over the SYNOP arrays are greatly in error. The continuous assimilation of the localized SYNOP data sets with a strong weight is necessary to obtain local realistic evolutions. Then assimilation of velocity measurements alone recovers the density structure over the array area. However, the spatial coverage of the SYNOP measurements is too small to constrain the model on the global scale. Thus the blending of both types of datasets is necessary in the assimilation as they constrain different time and space scales. Our choice of "gentle" nudging weight for the global OTIS 3 and "strong" weight for the local SYNOP data provides for realistic simulations of the Gulf Stream system, both globally and locally, on the 3- to 4-month-long timescale, the one governed by the Gulf Stream jet internal dynamics.

Interactive computation of coverage regions for indoor wireless communication

NASA Astrophysics Data System (ADS)

Abbott, A. Lynn; Bhat, Nitin; Rappaport, Theodore S.

1995-12-01

This paper describes a system which assists in the strategic placement of rf base stations within buildings. Known as the site modeling tool (SMT), this system allows the user to display graphical floor plans and to select base station transceiver parameters, including location and orientation, interactively. The system then computes and highlights estimated coverage regions for each transceiver, enabling the user to assess the total coverage within the building. For single-floor operation, the user can choose between distance-dependent and partition- dependent path-loss models. Similar path-loss models are also available for the case of multiple floors. This paper describes the method used by the system to estimate coverage for both directional and omnidirectional antennas. The site modeling tool is intended to be simple to use by individuals who are not experts at wireless communication system design, and is expected to be very useful in the specification of indoor wireless systems.

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MedlinePlus

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Drivers of routine immunization coverage improvement in Africa: findings from district-level case studies

PubMed Central

LaFond, Anne; Kanagat, Natasha; Steinglass, Robert; Fields, Rebecca; Sequeira, Jenny; Mookherji, Sangeeta

2015-01-01

There is limited understanding of why routine immunization (RI) coverage improves in some settings in Africa and not in others. Using a grounded theory approach, we conducted in-depth case studies to understand pathways to coverage improvement by comparing immunization programme experience in 12 districts in three countries (Ethiopia, Cameroon and Ghana). Drawing on positive deviance or assets model techniques we compared the experience of districts where diphtheria–tetanus–pertussis (DTP3)/pentavalent3 (Penta3) coverage improved with districts where DTP3/Penta3 coverage remained unchanged (or steady) over the same period, focusing on basic readiness to deliver immunization services and drivers of coverage improvement. The results informed a model for immunization coverage improvement that emphasizes the dynamics of immunization systems at district level. In all districts, whether improving or steady, we found that a set of basic RI system resources were in place from 2006 to 2010 and did not observe major differences in infrastructure. We found that the differences in coverage trends were due to factors other than basic RI system capacity or service readiness. We identified six common drivers of RI coverage performance improvement—four direct drivers and two enabling drivers—that were present in well-performing districts and weaker or absent in steady coverage districts, and map the pathways from driver to improved supply, demand and coverage. Findings emphasize the critical role of implementation strategies and the need for locally skilled managers that are capable of tailoring strategies to specific settings and community needs. The case studies are unique in their focus on the positive drivers of change and the identification of pathways to coverage improvement, an approach that should be considered in future studies and routine assessments of district-level immunization system performance. PMID:24615431

BRICS countries and the global movement for universal health coverage.

PubMed

Tediosi, Fabrizio; Finch, Aureliano; Procacci, Christina; Marten, Robert; Missoni, Eduardo

2016-07-01

This article explores BRICS' engagement in the global movement for Universal Health Coverage (UHC) and the implications for global health governance. It is based on primary data collected from 43 key informant interviews, complemented by a review of BRICS' global commitments supporting UHC. Interviews were conducted using a semi-structured questionnaire that included both closed- and open-ended questions. Question development was informed by insights from the literature on UHC, Cox's framework for action, and Kingdon's multiple-stream theory of policy formation. The closed questions were analysed with simple descriptive statistics and the open-ended questions using grounded theory approach. The analysis demonstrates that most BRICS countries implicitly supported the global movement for UHC, and that they share an active engagement in promoting UHC. However, only Brazil, China and to some extent South Africa, were recognized as proactively pushing UHC in the global agenda. In addition, despite some concerted actions, BRICS countries seem to act more as individual countries rather that as an allied group. These findings suggest that BRICS are unlikely to be a unified political block that will transform global health governance. Yet the documented involvement of BRICS in the global movement supporting UHC, and their focus on domestic challenges, shows that BRICS individually are increasingly influential players in global health. So if BRICS countries should probably not be portrayed as the centre of future political community that will transform global health governance, their individual involvement in global health, and their documented concerted actions, may give greater voice to low- and middle-income countries supporting the emergence of multiple centres of powers in global health. © The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Global Estimates of Syphilis in Pregnancy and Associated Adverse Outcomes: Analysis of Multinational Antenatal Surveillance Data

PubMed Central

Newman, Lori; Kamb, Mary; Hawkes, Sarah; Gomez, Gabriela; Say, Lale; Seuc, Armando; Broutet, Nathalie

2013-01-01

Background The World Health Organization initiative to eliminate mother-to-child transmission of syphilis aims for ≥90% of pregnant women to be tested for syphilis and ≥90% to receive treatment by 2015. We calculated global and regional estimates of syphilis in pregnancy and associated adverse outcomes for 2008, as well as antenatal care (ANC) coverage for women with syphilis. Methods and Findings Estimates were based upon a health service delivery model. National syphilis seropositivity data from 97 of 193 countries and ANC coverage from 147 countries were obtained from World Health Organization databases. Proportions of adverse outcomes and effectiveness of screening and treatment were from published literature. Regional estimates of ANC syphilis testing and treatment were examined through sensitivity analysis. In 2008, approximately 1.36 million (range: 1.16 to 1.56 million) pregnant women globally were estimated to have probable active syphilis; of these, 80% had attended ANC. Globally, 520,905 (best case: 425,847; worst case: 615,963) adverse outcomes were estimated to be caused by maternal syphilis, including approximately 212,327 (174,938; 249,716) stillbirths (>28 wk) or early fetal deaths (22 to 28 wk), 91,764 (76,141; 107,397) neonatal deaths, 65,267 (56,929; 73,605) preterm or low birth weight infants, and 151,547 (117,848; 185,245) infected newborns. Approximately 66% of adverse outcomes occurred in ANC attendees who were not tested or were not treated for syphilis. In 2008, based on the middle case scenario, clinical services likely averted 26% of all adverse outcomes. Limitations include missing syphilis seropositivity data for many countries in Europe, the Mediterranean, and North America, and use of estimates for the proportion of syphilis that was “probable active,” and for testing and treatment coverage. Conclusions Syphilis continues to affect large numbers of pregnant women, causing substantial perinatal morbidity and mortality that could be prevented by early testing and treatment. In this analysis, most adverse outcomes occurred among women who attended ANC but were not tested or treated for syphilis, highlighting the need to improve the quality of ANC as well as ANC coverage. In addition, improved ANC data on syphilis testing coverage, positivity, and treatment are needed. Please see later in the article for the Editors' Summary PMID:23468598

Global estimates of syphilis in pregnancy and associated adverse outcomes: analysis of multinational antenatal surveillance data.

PubMed

Newman, Lori; Kamb, Mary; Hawkes, Sarah; Gomez, Gabriela; Say, Lale; Seuc, Armando; Broutet, Nathalie

2013-01-01

The World Health Organization initiative to eliminate mother-to-child transmission of syphilis aims for ≥ 90% of pregnant women to be tested for syphilis and ≥ 90% to receive treatment by 2015. We calculated global and regional estimates of syphilis in pregnancy and associated adverse outcomes for 2008, as well as antenatal care (ANC) coverage for women with syphilis. Estimates were based upon a health service delivery model. National syphilis seropositivity data from 97 of 193 countries and ANC coverage from 147 countries were obtained from World Health Organization databases. Proportions of adverse outcomes and effectiveness of screening and treatment were from published literature. Regional estimates of ANC syphilis testing and treatment were examined through sensitivity analysis. In 2008, approximately 1.36 million (range: 1.16 to 1.56 million) pregnant women globally were estimated to have probable active syphilis; of these, 80% had attended ANC. Globally, 520,905 (best case: 425,847; worst case: 615,963) adverse outcomes were estimated to be caused by maternal syphilis, including approximately 212,327 (174,938; 249,716) stillbirths (>28 wk) or early fetal deaths (22 to 28 wk), 91,764 (76,141; 107,397) neonatal deaths, 65,267 (56,929; 73,605) preterm or low birth weight infants, and 151,547 (117,848; 185,245) infected newborns. Approximately 66% of adverse outcomes occurred in ANC attendees who were not tested or were not treated for syphilis. In 2008, based on the middle case scenario, clinical services likely averted 26% of all adverse outcomes. Limitations include missing syphilis seropositivity data for many countries in Europe, the Mediterranean, and North America, and use of estimates for the proportion of syphilis that was "probable active," and for testing and treatment coverage. Syphilis continues to affect large numbers of pregnant women, causing substantial perinatal morbidity and mortality that could be prevented by early testing and treatment. In this analysis, most adverse outcomes occurred among women who attended ANC but were not tested or treated for syphilis, highlighting the need to improve the quality of ANC as well as ANC coverage. In addition, improved ANC data on syphilis testing coverage, positivity, and treatment are needed. Please see later in the article for the Editors' Summary.

Combining XCO2 Measurements Derived from SCIAMACHY and GOSAT for Potentially Generating Global CO2 Maps with High Spatiotemporal Resolution

PubMed Central

Wang, Tianxing; Shi, Jiancheng; Jing, Yingying; Zhao, Tianjie; Ji, Dabin; Xiong, Chuan

2014-01-01

Global warming induced by atmospheric CO2 has attracted increasing attention of researchers all over the world. Although space-based technology provides the ability to map atmospheric CO2 globally, the number of valid CO2 measurements is generally limited for certain instruments owing to the presence of clouds, which in turn constrain the studies of global CO2 sources and sinks. Thus, it is a potentially promising work to combine the currently available CO2 measurements. In this study, a strategy for fusing SCIAMACHY and GOSAT CO2 measurements is proposed by fully considering the CO2 global bias, averaging kernel, and spatiotemporal variations as well as the CO2 retrieval errors. Based on this method, a global CO2 map with certain UTC time can also be generated by employing the pattern of the CO2 daily cycle reflected by Carbon Tracker (CT) data. The results reveal that relative to GOSAT, the global spatial coverage of the combined CO2 map increased by 41.3% and 47.7% on a daily and monthly scale, respectively, and even higher when compared with that relative to SCIAMACHY. The findings in this paper prove the effectiveness of the combination method in supporting the generation of global full-coverage XCO2 maps with higher temporal and spatial sampling by jointly using these two space-based XCO2 datasets. PMID:25119468

Expanding insurance coverage through tax credits, consumer choice, and market enhancements: the American Medical Association proposal for health insurance reform.

PubMed

Palmisano, Donald J; Emmons, David W; Wozniak, Gregory D

2004-05-12

Recent reports showing an increase in the number of uninsured individuals in the United States have given heightened attention to increasing health insurance coverage. The American Medical Association (AMA) has proposed a system of tax credits for the purchase of individually owned health insurance and enhancements to individual and group health insurance markets as a means of expanding coverage. Individually owned insurance would enable people to maintain coverage without disruption to existing patient-physician relationships, regardless of changes in employers or in work status. The AMA's plan would empower individuals to choose their health plan and give patients and their physicians more control over health care choices. Employers could continue to offer employment-based coverage, but employees would not be limited to the health plans offered by their employer. With a tax credit large enough to make coverage affordable and the ability to choose their own coverage, consumers would dramatically transform the individual and group health insurance markets. Health insurers would respond to the demands of individual consumers and be more cautious about increasing premiums. Insurers would also tailor benefit packages and develop new forms of coverage to better match the preferences of individuals and families. The AMA supports the development of new health insurance markets through legislative and regulatory changes to foster a wider array of high-quality, affordable plans.

Limited impact on decadal-scale climate change from increased use of natural gas.

PubMed

McJeon, Haewon; Edmonds, Jae; Bauer, Nico; Clarke, Leon; Fisher, Brian; Flannery, Brian P; Hilaire, Jérôme; Krey, Volker; Marangoni, Giacomo; Mi, Raymond; Riahi, Keywan; Rogner, Holger; Tavoni, Massimo

2014-10-23

The most important energy development of the past decade has been the wide deployment of hydraulic fracturing technologies that enable the production of previously uneconomic shale gas resources in North America. If these advanced gas production technologies were to be deployed globally, the energy market could see a large influx of economically competitive unconventional gas resources. The climate implications of such abundant natural gas have been hotly debated. Some researchers have observed that abundant natural gas substituting for coal could reduce carbon dioxide (CO2) emissions. Others have reported that the non-CO2 greenhouse gas emissions associated with shale gas production make its lifecycle emissions higher than those of coal. Assessment of the full impact of abundant gas on climate change requires an integrated approach to the global energy-economy-climate systems, but the literature has been limited in either its geographic scope or its coverage of greenhouse gases. Here we show that market-driven increases in global supplies of unconventional natural gas do not discernibly reduce the trajectory of greenhouse gas emissions or climate forcing. Our results, based on simulations from five state-of-the-art integrated assessment models of energy-economy-climate systems independently forced by an abundant gas scenario, project large additional natural gas consumption of up to +170 per cent by 2050. The impact on CO2 emissions, however, is found to be much smaller (from -2 per cent to +11 per cent), and a majority of the models reported a small increase in climate forcing (from -0.3 per cent to +7 per cent) associated with the increased use of abundant gas. Our results show that although market penetration of globally abundant gas may substantially change the future energy system, it is not necessarily an effective substitute for climate change mitigation policy.

The Miniature Radio Frequency Instruments (Mini-RF) Global Observations of Earth's Moon

NASA Technical Reports Server (NTRS)

Cahill, Joshua T. S.; Thomson, B. J.; Patterson, G. Wesley; Bussey, D. Benjamin J.; Neish, Catherine D.; Lopez, Norberto R.; Turner, F. Scott; Aldridge, T.; McAdam, M.; Meyer, H. M.;

Coupled fvGCM-GCE Modeling System, TRMM Latent Heating and Cloud Library

NASA Technical Reports Server (NTRS)

Tao, Wei-Kuo

2004-01-01

Recent GEWEX Cloud System Study (GCSS) model comparison projects have indicated that cloud-resolving models (CRMs) agree with observations better than traditional single-column models in simulating various types of clouds and cloud systems from different geographic locations. Current and future NASA satellite programs can provide cloud, precipitation, aerosol and other data at very fine spatial and temporal scales. It requires a coupled global circulation model (GCM) and cloud-scale model (termed a super-parameterization or multi-scale modeling framework, MMF) to use these satellite data to imiprove the understanding of the physical processes that are responsible for the variation in global and regional climate and hydrological systems. The use of a GCM will enable global coverage, and the use of a CRM will allow for better and more sophisticated physical parameterization. NASA satellite and field campaign cloud related datasets can provide initial conditions as well as validation for both the MMF and CRMs. A seed fund is available at NASA Goddard to build a MMF based on the 2D GCE model and the Goddard finite volume general circulation model (fvGCM). A prototype MMF will be developed by the end of 2004 and production runs will be conducted at the beginning of 2005. The purpose of this proposal is to augment the current Goddard MMF and other cloud modeling activities. I this talk, I will present: (1) A summary of the second Cloud Modeling Workshop took place at NASA Goddard, (2) A summary of the third TRMM Latent Heating Workshop took place at Nara Japan, (3) A brief discussion on the Goddard research plan of using Weather Research Forecast (WRF) model, and (4) A brief discussion on the GCE model on developing a global cloud simulator.

Coupled fvGCM-GCE Modeling System: TRMM Latent Heating and Cloud Library

NASA Technical Reports Server (NTRS)

Tao, Wei-Kuo

2005-01-01

Recent GEWEX Cloud System Study (GCSS) model comparison projects have indicated that cloud-resolving models (CRMs) agree with observations better than traditional single-column models in simulating various types of clouds and cloud systems from different geographic locations. Current and future NASA satellite programs can provide cloud, precipitation, aerosol and other data at very fine spatial and temporal scales. It requires a coupled global circulation model (GCM) and cloud-scale model (termed a super-parameterization or multi-scale modeling framework, MMF) to use these satellite data to improve the understanding of the physical processes that are responsible for the variation in global and regional climate and hydrological systems. The use of a GCM will enable global coverage, and the use of a CRM will allow for better and more sophisticated physical parameterization. NASA satellite and field campaign cloud related datasets can provide initial conditions as well as validation for both the MMF and CRMs. A seed fund is available at NASA Goddard to build a MMF based on the 2D GCE model and the Goddard finite volume general circulation model (fvGCM). A prototype MMF will be developed by the end of 2004 and production runs will be conducted at the beginning of 2005. The purpose of this proposal is to augment the current Goddard MMF and other cloud modeling activities. In this talk, I will present: (1) A summary of the second Cloud Modeling Workshop took place at NASA Goddard, (2) A summary of the third TRMM Latent Heating Workshop took place at Nara Japan, (3) A brief discussion on the GCE model on developing a global cloud simulator.

Coupled fvGCM-GCE Modeling System, 3D Cloud-Resolving Model and Cloud Library

NASA Technical Reports Server (NTRS)

Tao, Wei-Kuo

2005-01-01

Recent GEWEX Cloud System Study (GCSS) model comparison projects have indicated that cloud- resolving models (CRMs) agree with observations better than traditional single-column models in simulating various types of clouds and cloud systems from different geographic locations. Current and future NASA satellite programs can provide cloud, precipitation, aerosol and other data at very fine spatial and temporal scales. It requires a coupled global circulation model (GCM) and cloud-scale model (termed a super-parameterization or multi-scale modeling framework, MMF) to use these satellite data to improve the understanding of the physical processes that are responsible for the variation in global and regional climate and hydrological systems. The use of a GCM will enable global coverage, and the use of a CRM will allow for better and more sophisticated physical parameterization. NASA satellite and field campaign cloud related datasets can provide initial conditions as well as validation for both the MMF and CRMs. A seed fund is available at NASA Goddard to build a MMF based on the 2D Goddard Cumulus Ensemble (GCE) model and the Goddard finite volume general circulation model (fvGCM). A prototype MMF in being developed and production runs will be conducted at the beginning of 2005. In this talk, I will present: (1) A brief review on GCE model and its applications on precipitation processes, ( 2 ) The Goddard MMF and the major difference between two existing MMFs (CSU MMF and Goddard MMF), (3) A cloud library generated by Goddard MMF, and 3D GCE model, and (4) A brief discussion on the GCE model on developing a global cloud simulator.

Surface wave tomography of North America and the Caribbean using global and regional broad-band networks: Phase velocity maps and limitations of ray theory

USGS Publications Warehouse

Godey, S.; Snieder, R.; Villasenor, A.; Benz, H.M.

2003-01-01

We present phase velocity maps of fundamental mode Rayleigh waves across the North American and Caribbean plates. Our data set consists of 1846 waveforms from 172 events recorded at 91 broad-band stations operating in North America. We compute phase velocity maps in four narrow period bands between 50 and 150 s using a non-linear waveform inversion method that solves for phase velocity perturbations relative to a reference Earth model (PREM). Our results show a strong velocity contrast between high velocities beneath the stable North American craton, and lower velocities in the tectonically active western margin, in agreement with other regional and global surface wave tomography studies. We perform detailed comparisons with global model results, which display good agreement between phase velocity maps in the location and amplitude of the anomalies. However, forward modelling shows that regional maps are more accurate for predicting waveforms. In addition, at long periods, the amplitude of the velocity anomalies imaged in our regional phase velocity maps is three time larger than in global phase velocity models. This amplitude factor is necessary to explain the data accurately, showing that regional models provide a better image of velocity structures. Synthetic tests show that the raypath coverage used in this study enables one to resolve velocity features of the order of 800-1000 km. However, only larger length-scale features are observed in the phase velocity maps. The limitation in resolution of our maps can be attributed to the wave propagation theory used in the inversion. Ray theory does not account for off-great-circle ray propagation effects, such as ray bending or scattering. For wavelengths less than 1000 km, scattering effects are significant and may need to be considered.

Mars Operational Environmental Satellite (MOES): A post-Mars Observer discovery mission

NASA Technical Reports Server (NTRS)

Limaye, Sanjay S.

1993-01-01

Mars Operational Environmental Satellite (MOES) is a Discovery concept mission that is designed to observe the global short-term weather phenomena on Mars in a systematic fashion. Even after the Mariner, Viking, and, soon, Mars Observer missions, crucial aspects of the martian atmosphere will remain unobserved systematically. Achieving a better understanding of the cycles of dust, water vapor, and ices on Mars requires detailed information about atmospheric transports of those quantities associated with the weather systems, particularly those arising in mid latitudes during fall and winter. It also requires a quantitive understanding of the processes responsible for the onset and evolution of dust storms on all scales. Whereas on Earth the system of geosynchronous and polar orbiting satellites provides continuous coverage of the weather systems, on Mars the time history of important events such as regional and global dust storms remains unobserved. To understand the transport of tracers in the martian atmosphere and particularly to identify their sources and sinks, it is necessary to have systematic global, synoptic observations that have yet to be attained. Clearly these requirements are not easy to achieve from a single spacecraft in orbit, but if we focus on specific regions of the planet, e.g., polar vs. low and mid latitudes, then it is possible to attain a nearly ideal coverage at a reasonable spatial and temporal resolution with a system of just two satellites. Mars Observer is about to yield good coverage of the polar latitudes, so we focus initially on the region not covered well in terms of diurnal coverage, and in terms of desired observations will provide the initial data for the numerical models of the martian weather and climate that can be verified only with better temporal and spatial data.

Front-End Electron Transfer Dissociation Coupled to a 21 Tesla FT-ICR Mass Spectrometer for Intact Protein Sequence Analysis

NASA Astrophysics Data System (ADS)

Weisbrod, Chad R.; Kaiser, Nathan K.; Syka, John E. P.; Early, Lee; Mullen, Christopher; Dunyach, Jean-Jacques; English, A. Michelle; Anderson, Lissa C.; Blakney, Greg T.; Shabanowitz, Jeffrey; Hendrickson, Christopher L.; Marshall, Alan G.; Hunt, Donald F.

2017-09-01

High resolution mass spectrometry is a key technology for in-depth protein characterization. High-field Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) enables high-level interrogation of intact proteins in the most detail to date. However, an appropriate complement of fragmentation technologies must be paired with FTMS to provide comprehensive sequence coverage, as well as characterization of sequence variants, and post-translational modifications. Here we describe the integration of front-end electron transfer dissociation (FETD) with a custom-built 21 tesla FT-ICR mass spectrometer, which yields unprecedented sequence coverage for proteins ranging from 2.8 to 29 kDa, without the need for extensive spectral averaging (e.g., 60% sequence coverage for apo-myoglobin with four averaged acquisitions). The system is equipped with a multipole storage device separate from the ETD reaction device, which allows accumulation of multiple ETD fragment ion fills. Consequently, an optimally large product ion population is accumulated prior to transfer to the ICR cell for mass analysis, which improves mass spectral signal-to-noise ratio, dynamic range, and scan rate. We find a linear relationship between protein molecular weight and minimum number of ETD reaction fills to achieve optimum sequence coverage, thereby enabling more efficient use of instrument data acquisition time. Finally, real-time scaling of the number of ETD reactions fills during method-based acquisition is shown, and the implications for LC-MS/MS top-down analysis are discussed. [Figure not available: see fulltext.

Automatic stent strut detection in intravascular OCT images using image processing and classification technique

NASA Astrophysics Data System (ADS)

Lu, Hong; Gargesha, Madhusudhana; Wang, Zhao; Chamie, Daniel; Attizani, Guilherme F.; Kanaya, Tomoaki; Ray, Soumya; Costa, Marco A.; Rollins, Andrew M.; Bezerra, Hiram G.; Wilson, David L.

2013-02-01

Intravascular OCT (iOCT) is an imaging modality with ideal resolution and contrast to provide accurate in vivo assessments of tissue healing following stent implantation. Our Cardiovascular Imaging Core Laboratory has served >20 international stent clinical trials with >2000 stents analyzed. Each stent requires 6-16hrs of manual analysis time and we are developing highly automated software to reduce this extreme effort. Using classification technique, physically meaningful image features, forward feature selection to limit overtraining, and leave-one-stent-out cross validation, we detected stent struts. To determine tissue coverage areas, we estimated stent "contours" by fitting detected struts and interpolation points from linearly interpolated tissue depths to a periodic cubic spline. Tissue coverage area was obtained by subtracting lumen area from the stent area. Detection was compared against manual analysis of 40 pullbacks. We obtained recall = 90+/-3% and precision = 89+/-6%. When taking struts deemed not bright enough for manual analysis into consideration, precision improved to 94+/-6%. This approached inter-observer variability (recall = 93%, precision = 96%). Differences in stent and tissue coverage areas are 0.12 +/- 0.41 mm2 and 0.09 +/- 0.42 mm2, respectively. We are developing software which will enable visualization, review, and editing of automated results, so as to provide a comprehensive stent analysis package. This should enable better and cheaper stent clinical trials, so that manufacturers can optimize the myriad of parameters (drug, coverage, bioresorbable versus metal, etc.) for stent design.

Lunar-based Earth observation geometrical characteristics research

NASA Astrophysics Data System (ADS)

Ren, Yuanzhen; Liu, Guang; Ye, Hanlin; Guo, Huadong; Ding, Yixing; Chen, Zhaoning

2016-07-01

As is known to all, there are various platforms for carrying sensors to observe Earth, such as automobiles, aircrafts and satellites. Nowadays, we focus on a new platform, Moon, because of its longevity, stability and vast space. These advantages make it to be the next potential platform for observing Earth, enabling us to get the consistent and global measurements. In order to get a better understanding of lunar-based Earth observation, we discuss its geometrical characteristics. At present, there are no sensors on the Moon for observing Earth and we are not able to obtain a series of real experiment data. As a result, theoretical modeling and numerical calculation are used in this paper. At first, we construct an approximate geometrical model of lunar-based Earth observation, which assumes that Earth and Moon are spheres. Next, we calculate the position of Sun, Earth and Moon based on the JPL ephemeris. With the help of positions data and geometrical model, it is possible for us to decide the location of terminator and substellar points. However, in order to determine their precise position in the conventional terrestrial coordinate system, reference frames transformations are introduced as well. Besides, taking advantages of the relative positions of Sun, Earth and Moon, we get the total coverage of lunar-based Earth optical observation. Furthermore, we calculate a more precise coverage, considering placing sensors on different positions of Moon, which is influenced by its attitude parameters. In addition, different ephemeris data are compared in our research and little difference is found.

The Norwegian immunisation register--SYSVAK.

PubMed

Trogstad, L; Ung, G; Hagerup-Jenssen, M; Cappelen, I; Haugen, I L; Feiring, B

2012-04-19

The Norwegian immunisation register, SYSVAK, is a national electronic immunisation register. It became nationwide in 1995. The major aim was to register all vaccinations in the Childhood Immunisation Programme to ensure that all children are offered adequate vaccination according to schedule in the programme, and to secure high vaccination coverage. Notification to SYSVAK is mandatory, based on personal identification numbers. This allows follow up of individual vaccination schedules and linkage of SYSVAK data to other national health registers for information on outcome diagnoses, such as the surveillance system for communicable diseases. Information from SYSVAK is used to determine vaccine coverage in a timely manner. Coverage can be broken down to regional/local levels and used for active surveillance of vaccination coverage and decisions about interventions. During the 2009 influenza A(H1N1)pdm09 pandemic, an adaptation of SYSVAK enabled daily surveillance of vaccination coverage on national and regional levels. Currently, data from SYSVAK are used, among others, in studies on adverse events related to pandemic vaccination. Future challenges include maximising usage of collected data in surveillance and research, and continued improvement of data quality. Immunisation registers are rich sources for high quality surveillance of vaccination coverage, effectiveness, vaccine failure and adverse events, and gold mines for research.

Health-system reform and universal health coverage in Latin America.

PubMed

Atun, Rifat; de Andrade, Luiz Odorico Monteiro; Almeida, Gisele; Cotlear, Daniel; Dmytraczenko, T; Frenz, Patricia; Garcia, Patrícia; Gómez-Dantés, Octavio; Knaul, Felicia M; Muntaner, Carles; de Paula, Juliana Braga; Rígoli, Felix; Serrate, Pastor Castell-Florit; Wagstaff, Adam

2015-03-28

Starting in the late 1980s, many Latin American countries began social sector reforms to alleviate poverty, reduce socioeconomic inequalities, improve health outcomes, and provide financial risk protection. In particular, starting in the 1990s, reforms aimed at strengthening health systems to reduce inequalities in health access and outcomes focused on expansion of universal health coverage, especially for poor citizens. In Latin America, health-system reforms have produced a distinct approach to universal health coverage, underpinned by the principles of equity, solidarity, and collective action to overcome social inequalities. In most of the countries studied, government financing enabled the introduction of supply-side interventions to expand insurance coverage for uninsured citizens--with defined and enlarged benefits packages--and to scale up delivery of health services. Countries such as Brazil and Cuba introduced tax-financed universal health systems. These changes were combined with demand-side interventions aimed at alleviating poverty (targeting many social determinants of health) and improving access of the most disadvantaged populations. Hence, the distinguishing features of health-system strengthening for universal health coverage and lessons from the Latin American experience are relevant for countries advancing universal health coverage. Copyright © 2015 Elsevier Ltd. All rights reserved.

Quantitative maps of genetic interactions in yeast - comparative evaluation and integrative analysis.

PubMed

Lindén, Rolf O; Eronen, Ville-Pekka; Aittokallio, Tero

2011-03-24

High-throughput genetic screening approaches have enabled systematic means to study how interactions among gene mutations contribute to quantitative fitness phenotypes, with the aim of providing insights into the functional wiring diagrams of genetic interaction networks on a global scale. However, it is poorly known how well these quantitative interaction measurements agree across the screening approaches, which hinders their integrated use toward improving the coverage and quality of the genetic interaction maps in yeast and other organisms. Using large-scale data matrices from epistatic miniarray profiling (E-MAP), genetic interaction mapping (GIM), and synthetic genetic array (SGA) approaches, we carried out here a systematic comparative evaluation among these quantitative maps of genetic interactions in yeast. The relatively low association between the original interaction measurements or their customized scores could be improved using a matrix-based modelling framework, which enables the use of single- and double-mutant fitness estimates and measurements, respectively, when scoring genetic interactions. Toward an integrative analysis, we show how the detections from the different screening approaches can be combined to suggest novel positive and negative interactions which are complementary to those obtained using any single screening approach alone. The matrix approximation procedure has been made available to support the design and analysis of the future screening studies. We have shown here that even if the correlation between the currently available quantitative genetic interaction maps in yeast is relatively low, their comparability can be improved by means of our computational matrix approximation procedure, which will enable integrative analysis and detection of a wider spectrum of genetic interactions using data from the complementary screening approaches.

Global tree network for computing structures enabling global processing operations

DOEpatents

Blumrich; Matthias A.; Chen, Dong; Coteus, Paul W.; Gara, Alan G.; Giampapa, Mark E.; Heidelberger, Philip; Hoenicke, Dirk; Steinmacher-Burow, Burkhard D.; Takken, Todd E.; Vranas, Pavlos M.

2010-01-19

A system and method for enabling high-speed, low-latency global tree network communications among processing nodes interconnected according to a tree network structure. The global tree network enables collective reduction operations to be performed during parallel algorithm operations executing in a computer structure having a plurality of the interconnected processing nodes. Router devices are included that interconnect the nodes of the tree via links to facilitate performance of low-latency global processing operations at nodes of the virtual tree and sub-tree structures. The global operations performed include one or more of: broadcast operations downstream from a root node to leaf nodes of a virtual tree, reduction operations upstream from leaf nodes to the root node in the virtual tree, and point-to-point message passing from any node to the root node. The global tree network is configurable to provide global barrier and interrupt functionality in asynchronous or synchronized manner, and, is physically and logically partitionable.

Spatio-temporal variation of vegetation coverage and its response to climate change in North China plain in the last 33 years

NASA Astrophysics Data System (ADS)

A, Duo; Zhao, Wenji; Qu, Xinyuan; Jing, Ran; Xiong, Kai

2016-12-01

Global climate change has led to significant vegetation changes in the past half century. North China Plain, the most important grain production base of china, is undergoing a process of prominent warming and drying. The vegetation coverage, which is used to monitor vegetation change, can respond to climate change (temperature and precipitation). In this study, GIMMS (Global Inventory Modelling and Mapping Studies)-NDVI (Normalized Difference Vegetation Index) data, MODIS (Moderate-resolution Imaging Spectroradiometer) - NDVI data and climate data, during 1981-2013, were used to investigate the spatial distribution and changes of vegetation. The relationship between climate and vegetation on different spatial (agriculture, forest and grassland) and temporal (yearly, decadal and monthly) scales were also analyzed in North China Plain. (1) It was found that temperature exhibiting a slight increase trend (0.20 °C/10a, P < 0.01). This may be due to the disappearance of 0 °C isotherm, the rise of spring temperature. At the same time, precipitation showed a significant reduction trend (-1.75 mm/10a, P > 0.05). The climate mutation period was during 1991-1994. (2) Vegetation coverage slight increase was observed in the 55% of total study area, with a change rate of 0.00039/10a. Human activities may not only accelerate the changes of the vegetation coverage, but also c effect to the rate of these changes. (3) Overall, the correlation between the vegetation coverage and climatic factor is higher in monthly scale than yearly scale. The correlation analysis between vegetation coverage and climate changes showed that annual vegetation coverage was better correlatend with precipitation in grassland biome; but it showed a better correlated with temperature i the agriculture biome and forest biome. In addition, the vegetation coverage had sensitive time-effect respond to precipitation. (4) The vegetation coverage showed the same increasing trend before and after the climatic variations, but the rate of increase slowed down. From the vegetation coverage point of view, the grassland ecological zone had an obvious response to the climatic variations, but the agricultural ecological zones showed a significant response from the vegetation coverage change rate point of view. The effect of human activity in degradation region was higher than that in improvement area. But after the climate abruptly changing, the effect of human activity in improvement area was higher than that in degradation region, and the influence of human activity will continue in the future.

Tropospheric Ozone Assessment Report: Database and Metrics Data of Global Surface Ozone Observations

DOE PAGES

Schultz, Martin G.; Schroder, Sabine; Lyapina, Olga; ...

2017-11-27

In support of the first Tropospheric Ozone Assessment Report (TOAR) a relational database of global surface ozone observations has been developed and populated with hourly measurement data and enhanced metadata. A comprehensive suite of ozone data products including standard statistics, health and vegetation impact metrics, and trend information, are made available through a common data portal and a web interface. These data form the basis of the TOAR analyses focusing on human health, vegetation, and climate relevant ozone issues, which are part of this special feature. Cooperation among many data centers and individual researchers worldwide made it possible to buildmore » the world's largest collection of in-situ hourly surface ozone data covering the period from 1970 to 2015. By combining the data from almost 10,000 measurement sites around the world with global metadata information, new analyses of surface ozone have become possible, such as the first globally consistent characterisations of measurement sites as either urban or rural/remote. Exploitation of these global metadata allows for new insights into the global distribution, and seasonal and long-term changes of tropospheric ozone and they enable TOAR to perform the first, globally consistent analysis of present-day ozone concentrations and recent ozone changes with relevance to health, agriculture, and climate. Considerable effort was made to harmonize and synthesize data formats and metadata information from various networks and individual data submissions. Extensive quality control was applied to identify questionable and erroneous data, including changes in apparent instrument offsets or calibrations. Such data were excluded from TOAR data products. Limitations of a posteriori data quality assurance are discussed. As a result of the work presented here, global coverage of surface ozone data for scientific analysis has been significantly extended. Yet, large gaps remain in the surface observation network both in terms of regions without monitoring, and in terms of regions that have monitoring programs but no public access to the data archive. Therefore future improvements to the database will require not only improved data harmonization, but also expanded data sharing and increased monitoring in data-sparse regions.« less

Tropospheric Ozone Assessment Report: Database and Metrics Data of Global Surface Ozone Observations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schultz, Martin G.; Schroder, Sabine; Lyapina, Olga

In support of the first Tropospheric Ozone Assessment Report (TOAR) a relational database of global surface ozone observations has been developed and populated with hourly measurement data and enhanced metadata. A comprehensive suite of ozone data products including standard statistics, health and vegetation impact metrics, and trend information, are made available through a common data portal and a web interface. These data form the basis of the TOAR analyses focusing on human health, vegetation, and climate relevant ozone issues, which are part of this special feature. Cooperation among many data centers and individual researchers worldwide made it possible to buildmore » the world's largest collection of in-situ hourly surface ozone data covering the period from 1970 to 2015. By combining the data from almost 10,000 measurement sites around the world with global metadata information, new analyses of surface ozone have become possible, such as the first globally consistent characterisations of measurement sites as either urban or rural/remote. Exploitation of these global metadata allows for new insights into the global distribution, and seasonal and long-term changes of tropospheric ozone and they enable TOAR to perform the first, globally consistent analysis of present-day ozone concentrations and recent ozone changes with relevance to health, agriculture, and climate. Considerable effort was made to harmonize and synthesize data formats and metadata information from various networks and individual data submissions. Extensive quality control was applied to identify questionable and erroneous data, including changes in apparent instrument offsets or calibrations. Such data were excluded from TOAR data products. Limitations of a posteriori data quality assurance are discussed. As a result of the work presented here, global coverage of surface ozone data for scientific analysis has been significantly extended. Yet, large gaps remain in the surface observation network both in terms of regions without monitoring, and in terms of regions that have monitoring programs but no public access to the data archive. Therefore future improvements to the database will require not only improved data harmonization, but also expanded data sharing and increased monitoring in data-sparse regions.« less

Global estimates of human papillomavirus vaccination coverage by region and income level: a pooled analysis.

PubMed

Bruni, Laia; Diaz, Mireia; Barrionuevo-Rosas, Leslie; Herrero, Rolando; Bray, Freddie; Bosch, F Xavier; de Sanjosé, Silvia; Castellsagué, Xavier

2016-07-01

Since 2006, many countries have implemented publicly funded human papillomavirus (HPV) immunisation programmes. However, global estimates of the extent and impact of vaccine coverage are still unavailable. We aimed to quantify worldwide cumulative coverage of publicly funded HPV immunisation programmes up to 2014, and the potential impact on future cervical cancer cases and deaths. Between Nov 1 and Dec 22, 2014, we systematically reviewed PubMed, Scopus, and official websites to identify HPV immunisation programmes worldwide, and retrieved age-specific HPV vaccination coverage rates up to October, 2014. To estimate the coverage and number of vaccinated women, retrieved coverage rates were converted into birth-cohort-specific rates, with an imputation algorithm to impute missing data, and applied to global population estimates and cervical cancer projections by country and income level. From June, 2006, to October, 2014, 64 countries nationally, four countries subnationally, and 12 overseas territories had implemented HPV immunisation programmes. An estimated 118 million women had been targeted through these programmes, but only 1% were from low-income or lower-middle-income countries. 47 million women (95% CI 39-55 million) received the full course of vaccine, representing a total population coverage of 1·4% (95% CI 1·1-1·6), and 59 million women (48-71 million) had received at least one dose, representing a total population coverage of 1·7% (1·4-2·1). In more developed regions, 33·6% (95% CI 25·9-41·7) of females aged 10-20 years received the full course of vaccine, compared with only 2·7% (1·8-3·6) of females in less developed regions. The impact of the vaccine will be higher in upper-middle-income countries (178 192 averted cases by age 75 years) than in high-income countries (165 033 averted cases), despite the lower number of vaccinated women (13·3 million vs 32·2 million). Many women from high-income and upper-middle-income countries have been vaccinated against HPV. However, populations with the highest incidence and mortality of disease remain largely unprotected. Rapid roll-out of the vaccine in low-income and middle-income countries might be the only feasible way to narrow present inequalities in cervical cancer burden and prevention. PATH, Instituto de Salud Carlos III, and Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR). Copyright © 2016 Bruni et al. Open Access article distributed under the terms of CC BY. Published by Elsevier Ltd.. All rights reserved.

A Hybrid-Cloud Science Data System Enabling Advanced Rapid Imaging & Analysis for Monitoring Hazards

NASA Astrophysics Data System (ADS)

Hua, H.; Owen, S. E.; Yun, S.; Lundgren, P.; Moore, A. W.; Fielding, E. J.; Radulescu, C.; Sacco, G.; Stough, T. M.; Mattmann, C. A.; Cervelli, P. F.; Poland, M. P.; Cruz, J.

2012-12-01

Volcanic eruptions, landslides, and levee failures are some examples of hazards that can be more accurately forecasted with sufficient monitoring of precursory ground deformation, such as the high-resolution measurements from GPS and InSAR. In addition, coherence and reflectivity change maps can be used to detect surface change due to lava flows, mudslides, tornadoes, floods, and other natural and man-made disasters. However, it is difficult for many volcano observatories and other monitoring agencies to process GPS and InSAR products in an automated scenario needed for continual monitoring of events. Additionally, numerous interoperability barriers exist in multi-sensor observation data access, preparation, and fusion to create actionable products. Combining high spatial resolution InSAR products with high temporal resolution GPS products--and automating this data preparation & processing across global-scale areas of interests--present an untapped science and monitoring opportunity. The global coverage offered by satellite-based SAR observations, and the rapidly expanding GPS networks, can provide orders of magnitude more data on these hazardous events if we have a data system that can efficiently and effectively analyze the voluminous raw data, and provide users the tools to access data from their regions of interest. Currently, combined GPS & InSAR time series are primarily generated for specific research applications, and are not implemented to run on large-scale continuous data sets and delivered to decision-making communities. We are developing an advanced service-oriented architecture for hazard monitoring leveraging NASA-funded algorithms and data management to enable both science and decision-making communities to monitor areas of interests via seamless data preparation, processing, and distribution. Our objectives: * Enable high-volume and low-latency automatic generation of NASA Solid Earth science data products (InSAR and GPS) to support hazards monitoring. * Facilitate NASA-USGS collaborations to share NASA InSAR and GPS data products, which are difficult to process in high-volume and low-latency, for decision-support. * Enable interoperable discovery, access, and sharing of NASA observations and derived actionable products, and between the observation and decision-making communities. * Enable their improved understanding through visualization, mining, and cross-agency sharing. Existing InSAR & GPS processing packages and other software are integrated for generating geodetic decision support monitoring products. We employ semantic and cloud-based data management and processing techniques for handling large data volumes, reducing end product latency, codifying data system information with semantics, and deploying interoperable services for actionable products to decision-making communities.

Volumetrically-Derived Global Navigation Satellite System Performance Assessment from the Earths Surface through the Terrestrial Service Volume and the Space Service Volume

NASA Technical Reports Server (NTRS)

Welch, Bryan W.

2016-01-01

NASA is participating in the International Committee on Global Navigation Satellite Systems (GNSS) (ICG)'s efforts towards demonstrating the benefits to the space user from the Earth's surface through the Terrestrial Service Volume (TSV) to the edge of the Space Service Volume (SSV), when a multi-GNSS solution space approach is utilized. The ICG Working Group: Enhancement of GNSS Performance, New Services and Capabilities has started a three phase analysis initiative as an outcome of recommendations at the ICG-10 meeting, in preparation for the ICG-11 meeting. The first phase of that increasing complexity and fidelity analysis initiative was recently expanded to compare nadir-facing and zenith-facing user hemispherical antenna coverage with omnidirectional antenna coverage at different distances of 8,000 km altitude and 36,000 km altitude. This report summarizes the performance using these antenna coverage techniques at distances ranging from 100 km altitude to 36,000 km to be all encompassing, as well as the volumetrically-derived system availability metrics.

Universal Health Coverage for Schizophrenia: A Global Mental Health Priority

PubMed Central

Patel, Vikram

2016-01-01

The growing momentum towards a global consensus on universal health coverage, alongside an acknowledgment of the urgency and importance of a comprehensive mental health action plan, offers a unique opportunity for a substantial scale-up of evidence-based interventions and packages of care for a range of mental disorders in all countries. There is a robust evidence base testifying to the effectiveness of drug and psychosocial interventions for people with schizophrenia and to the feasibility, acceptability and cost-effectiveness of the delivery of these interventions through a collaborative care model in low resource settings. While there are a number of barriers to scaling up this evidence, for eg, the finances needed to train and deploy community based workers and the lack of agency for people with schizophrenia, the experiences of some upper middle income countries show that sustained political commitment, allocation of transitional financial resources to develop community services, a commitment to an integrated approach with a strong role for community based institutions and providers, and a progressive realization of coverage are the key ingredients for scale up of services for schizophrenia. PMID:26245942

Comparative health system performance in six middle-income countries: cross-sectional analysis using World Health Organization study of global ageing and health.

PubMed

Alshamsan, Riyadh; Lee, John Tayu; Rana, Sangeeta; Areabi, Hasan; Millett, Christopher

2017-09-01

Objective To assess and compare health system performance across six middle-income countries that are strengthening their health systems in pursuit of universal health coverage. Design Cross-sectional analysis from the World Health Organization Study on global AGEing and adult health, collected between 2007 and 2010. Setting Six middle-income countries: China, Ghana, India, Mexico, Russia and South Africa. Participants Nationally representative sample of adults aged 50 years and older. Main outcome measures We present achievement against key indicators of health system performance across effectiveness, cost, access, patient-centredness and equity domains. Results We found areas of poor performance in prevention and management of chronic conditions, such as hypertension control and cancer screening coverage. We also found that cost remains a barrier to healthcare access in spite of insurance schemes. Finally, we found evidence of disparities across many indicators, particularly in the effectiveness and patient centredness domains. Conclusions These findings identify important focus areas for action and shared learning as these countries move towards achieving universal health coverage.

Comparative health system performance in six middle-income countries: cross-sectional analysis using World Health Organization study of global ageing and health

PubMed Central

Alshamsan, Riyadh; Lee, John Tayu; Rana, Sangeeta; Areabi, Hasan; Millett, Christopher

2017-01-01

Objective To assess and compare health system performance across six middle-income countries that are strengthening their health systems in pursuit of universal health coverage. Design Cross-sectional analysis from the World Health Organization Study on global AGEing and adult health, collected between 2007 and 2010. Setting Six middle-income countries: China, Ghana, India, Mexico, Russia and South Africa. Participants Nationally representative sample of adults aged 50 years and older. Main outcome measures We present achievement against key indicators of health system performance across effectiveness, cost, access, patient-centredness and equity domains. Results We found areas of poor performance in prevention and management of chronic conditions, such as hypertension control and cancer screening coverage. We also found that cost remains a barrier to healthcare access in spite of insurance schemes. Finally, we found evidence of disparities across many indicators, particularly in the effectiveness and patient centredness domains. Conclusions These findings identify important focus areas for action and shared learning as these countries move towards achieving universal health coverage. PMID:28895493

SARS: Down But Still a Threat

DTIC Science & Technology

2003-08-01

moving between rural areas, cities, and manufacturing centers in search of employment . • Asia has become a major hub for business and tourist...conference participants worldwide. Benefits of Globalization. Intense international media coverage facilitated by global communication networks...rethink the costs and benefits of concentrating investment in one country or region, however. • Over the last decade, China has attracted massive

Investing for Impact: The Global Fund Approach to Measurement of AIDS Response.

PubMed

Jain, Suman; Zorzi, Nathalie

2017-07-01

The Global Fund raises and invests nearly US$4 billion a year to support programs run in more than 140 countries. The Global Fund strategy 2012-2016 is focused on "Investing for Impact". In order to accomplish this, timely and accurate data are needed to inform strategies and prioritize activities to achieve greater coverage with quality services. Monitoring and evaluation is intrinsic to the Global Fund's system of performance-based funding. The Global Fund invests in strengthening measurement and reporting of results at all stages of the grant cycle. The Global Fund approach to measurement is based on three key principles-(1) simplified reporting: the Global Fund has updated its measurement guidance to focus on impact, coverage and quality with the use of a harmonized set of indicators. (2) Supporting data systems-based on a common framework developed and supported by partners, it promotes investment in five common data systems: routine reporting including HMIS; Surveys-population based and risk group surveys; Analysis, reviews and transparency; Administrative and financial data sources; and, Vital registration systems. (3) Strengthen data use: the Global Fund funding encourages use of data at all levels-national, subnational and site level. Countries do not automatically prioritize M&E but when guidance, tools and investments are available, there is high level utilization of M&E systems in program design, planning, implementation, and results reporting. An in-depth analysis of the available data helps the Global Fund and countries to direct investments towards interventions where impact could be achieved and focus on target population groups and geographic areas that are most affected.

Media coverage of smoke-free policies after their innovation.

PubMed

Thrasher, James F; Kim, Sei-Hill; Rose, India; Craft, Mary-Kathryn

2015-01-01

Smoke-free policies are critical to global tobacco control, and prior research on media coverage of smoke-free policies primarily focused on the period when they were first innovated; however, the scientific basis for smoke-free policies has broadened, and how media coverage has changed, if at all, is unknown. The authors characterized the actors, arguments, and favorability of media coverage of smoke-free policies from 2006 to 2009, by content-analyzing 452 news stories in the 4 primary newspapers in South Carolina. Most media coverage was favorable (45%) or mixed (43%) toward smoke-free policies, and negative coverage decreased over time (B = -1.001, SE = 0.326; p = .008). The most prevalent argument concerned the harms of secondhand smoke (44%). A higher percentage of articles mentioned economic arguments against (26%) than for (17%) smoke-free policies (χ(2) = 10.89, p < .01, for the difference between 26% and 17%), and these percentages did not change over time. Advocates and media should improve communications to more effectively represent scientific evidence regarding the null or positive impact of smoke-free policies on businesses.

Access to health care as a human right in international policy: critical reflections and contemporary challenges.

PubMed

Castillo, Camilo Hernán Manchola; Garrafa, Volnei; Cunha, Thiago; Hellmann, Fernando

2017-07-01

Using the United Nations (UN) and its subordinate body, the World Health Organization (WHO), as a frame of reference, this article explores access to healthcare as a human right in international intergovernmental policies. First, we look at how the theme of health is treated within the UN, focusing on the concept of global health. We then discuss the concept of global health from a human rights perspective and go on to outline the debate surrounding universal coverage versus universal access as a human right, addressing some important ethical questions. Thereafter, we discuss universal coverage versus universal access using the critical and constructivist theories of international relations as a frame of reference. Finally, it is concluded that, faced with the persistence of huge global health inequalities, the WHO began to reshape itself, leaving behind the notion of health as a human right and imposing the challenge of reducing the wide gap that separates international intergovernmental laws from reality.

Global coverage Mobile Satellite Systems: System availability versus channel propagation impairments

NASA Technical Reports Server (NTRS)

Sforza, M.; Buonomo, S.; Poiaresbaptista, J. P. V.

1993-01-01

Mobile Satellite Systems (MSS) in Highly Elliptical (HEO) and circular Earth orbits at Medium (MEO) and Low (LEO) altitudes have been intensively studied in the last few years as an effective means of providing global communication services. Such global coverage MSS networks are also expected to mitigate typical channel impairments usually encountered in geostationary Land Mobile Satellite (LMS) systems. In the design stages of these satellite networks, information regarding the mobile propagation channel is needed to assess the overall link availability versus elevation angle and environmental scenarios. For multisatellite LMS configurations, the mobile user on the Earth surface sees, at any given time, more than one satellite of the constellation. In our paper, it is shown that, under certain working assumptions regarding the statistics of the propagation channel, an improvement of the link availability may be achieved through the use of a multisatellite constellation. The analyses have been carried out using the European Space Agency (ESA) LMS propagation data base which presently covers a wide range of elevation angles and environmental scenarios.

Temporal variability of the surface and atmosphere of Mars: Viking Orbiter color observations

NASA Technical Reports Server (NTRS)

Mcewen, A. S.

1992-01-01

We are near the final stages in the processing of a large Viking Orbiter global color dataset. Mosaics from 57 spacecraft revolutions (or 'revs' hereafter) were produced, most in both red and violet or red, green, and violet filters. Phase angles range from 13 deg to 85 deg. A total of approximately 2000 frames were processed through radiometric calibration, cosmetic cleanup, geometric control, reprojection, and mosaicking into single-rev mosaics at a scale of 1 km/pixel. All of the mosaics are geometrically tied to the 1/256 deg/pixel Mars Digital Image Mosaic (MDIM). Photometric normalization is in progress, to be followed by production of a 'best coverage' global mosaic at a scale of 1/64 deg/pixel (0.923 km/pixel). Global coverage is near 100 percent in red-filter mosaics and 98 percent and 60 percent in corresponding violet- and green-filter mosaics, respectively. Soon after completion, all final datasets (including single-rev mosaics) will be distributed to the planetary community on compact disks.

Coverage-dependent adsorption and desorption of oxygen on Pd(100)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dunnen, Angela den; Jacobse, Leon; Wiegman, Sandra

2016-06-28

We have studied the adsorption and desorption of O{sub 2} on Pd(100) by supersonic molecular beam techniques and thermal desorption spectroscopy. Adsorption measurements on the bare surface confirm that O{sub 2} initially dissociates for all kinetic energies between 56 and 380 meV and surface temperatures between 100 and 600 K via a direct mechanism. At and below 150 K, continued adsorption leads to a combined O/O{sub 2} overlayer. Dissociation of molecularly bound O{sub 2} during a subsequent temperature ramp leads to unexpected high atomic oxygen coverages, which are also obtained at high incident energy and high surface temperature. At intermediatemore » temperatures and energies, these high final coverages are not obtained. Our results show that kinetic energy of the gas phase reactant and reaction energy dissipated during O{sub 2} dissociation on the cold surface both enable activated nucleation of high-coverage surface structures. We suggest that excitation of local substrate phonons may play a crucial role in oxygen dissociation at any coverage.« less

Addressing Medicaid/marketplace churn through multimarket plans: assessing the current state of play.

PubMed

Rosenbaum, Sara

2015-02-01

Both before and after the Affordable Care Act (ACA), the US health insurance system is characterized by fragmentation. Pre-ACA, this fragmentation included major coverage gaps, causing significant periods of coverage interruption, especially for lower-income people. The ACA does not end the problem of churning among sources of public financing, but it does hold the potential for enabling people to move among sources of coverage rather than go without insurance. Several strategies for reducing coverage churn exist, but none is foolproof and all are in their early stages. Thus the ability of issuers to participate across multiple public financing arrangements and to offer stable provider networks becomes crucial to achieving continuity of care. Interviews with nine companies involved in developing or operating multimarket strategies confirm the feasibility of this approach while revealing major challenges, especially the challenge of finding providers willing to treat members regardless of the source of coverage. Strategies for increasing multimarket plans and networks represent one of the great areas of future policy and operational focus. Copyright © 2015 by Duke University Press.

Barriers and enablers for iron folic acid (IFA) supplementation in pregnant women.

PubMed

Siekmans, Kendra; Roche, Marion; Kung'u, Jacqueline K; Desrochers, Rachelle E; De-Regil, Luz Maria

2017-12-22

In order to inform large scale supplementation programme design, we review and summarize the barriers and enablers for improved coverage and utilization of iron and folic acid (IFA) supplements by pregnant women in 7 countries in Africa and Asia. Mixed methods were used to analyse IFA supplementation programmes in Afghanistan, Bangladesh, Indonesia, Ethiopia, Kenya, Nigeria, and Senegal based on formative research conducted in 2012-2013. Qualitative data from focus-group discussions and interviews with women and service providers were used for content analysis to elicit common themes on barriers and enablers at internal, external, and relational levels. Anaemia symptoms in pregnancy are well known among women and health care providers in all countries, yet many women do not feel personally at risk. Broad awareness and increased coverage of facility-based antenatal care (ANC) make it an efficient delivery channel for IFA; however, first trimester access to IFA is hindered by beliefs about when to first attend ANC and preferences for disclosing pregnancy status. Variable access and poor quality ANC services, including insufficient IFA supplies and inadequate counselling to encourage consumption, are barriers to both coverage and adherence. Community-based delivery of IFA and referral to ANC provides earlier and more frequent access and opportunities for follow-up. Improving ANC access and quality is needed to facilitate IFA supplementation during pregnancy. Community-based delivery and counselling can address problems of timely and continuous access to supplements. Renewed investment in training for service providers and effective behaviour change designs are urgently needed to achieve the desired impact. © 2018 John Wiley & Sons Ltd.

Simulating the Agulhas system in global ocean models - nesting vs. multi-resolution unstructured meshes

NASA Astrophysics Data System (ADS)

Biastoch, Arne; Sein, Dmitry; Durgadoo, Jonathan V.; Wang, Qiang; Danilov, Sergey

2018-01-01

Many questions in ocean and climate modelling require the combined use of high resolution, global coverage and multi-decadal integration length. For this combination, even modern resources limit the use of traditional structured-mesh grids. Here we compare two approaches: A high-resolution grid nested into a global model at coarser resolution (NEMO with AGRIF) and an unstructured-mesh grid (FESOM) which allows to variably enhance resolution where desired. The Agulhas system around South Africa is used as a testcase, providing an energetic interplay of a strong western boundary current and mesoscale dynamics. Its open setting into the horizontal and global overturning circulations also requires global coverage. Both model configurations simulate a reasonable large-scale circulation. Distribution and temporal variability of the wind-driven circulation are quite comparable due to the same atmospheric forcing. However, the overturning circulation differs, owing each model's ability to represent formation and spreading of deep water masses. In terms of regional, high-resolution dynamics, all elements of the Agulhas system are well represented. Owing to the strong nonlinearity in the system, Agulhas Current transports of both configurations and in comparison with observations differ in strength and temporal variability. Similar decadal trends in Agulhas Current transport and Agulhas leakage are linked to the trends in wind forcing.

Assessment of the NASA-USGS Global Land Survey (GLS) Datasets

USGS Publications Warehouse

Gutman, Garik; Huang, Chengquan; Chander, Gyanesh; Noojipady, Praveen; Masek, Jeffery G.

2013-01-01

The Global Land Survey (GLS) datasets are a collection of orthorectified, cloud-minimized Landsat-type satellite images, providing near complete coverage of the global land area decadally since the early 1970s. The global mosaics are centered on 1975, 1990, 2000, 2005, and 2010, and consist of data acquired from four sensors: Enhanced Thematic Mapper Plus, Thematic Mapper, Multispectral Scanner, and Advanced Land Imager. The GLS datasets have been widely used in land-cover and land-use change studies at local, regional, and global scales. This study evaluates the GLS datasets with respect to their spatial coverage, temporal consistency, geodetic accuracy, radiometric calibration consistency, image completeness, extent of cloud contamination, and residual gaps. In general, the three latest GLS datasets are of a better quality than the GLS-1990 and GLS-1975 datasets, with most of the imagery (85%) having cloud cover of less than 10%, the acquisition years clustered much more tightly around their target years, better co-registration relative to GLS-2000, and better radiometric absolute calibration. Probably, the most significant impediment to scientific use of the datasets is the variability of image phenology (i.e., acquisition day of year). This paper provides end-users with an assessment of the quality of the GLS datasets for specific applications, and where possible, suggestions for mitigating their deficiencies.

Financial hardship on the path to Universal Health Coverage in the Gulf States.

PubMed

Alshamsan, Riyadh; Leslie, Hannah; Majeed, Azeem; Kruk, Margaret

2017-03-01

Countries globally are pursuing universal health coverage to ensure better healthcare for their populations and prevent households from catastrophic expenditure. The countries of the Gulf Cooperation Council (GCC) have and continue to implement reforms to strengthen their health systems. A common theme between the countries is their pursuit of universal health coverage to provide access to necessary health care without exposing people to financial hardship. Using nationally representative data from the Global Findex study, we sought to analyze the hardship faced by individuals from four high-income countries in the GCC. We estimated the weighted proportion of individuals borrowing for medical reasons and those who are not able to obtain emergency funds. We further examined variations in these outcomes by key socioeconomic factors. We found up to 11% of respondents borrowed money for medical purposes, double of that reported in other high-income countries. In contrast to affluent respondents, we found that respondents from deprived background were more likely to borrow money for medical purposes (adjusted odds ratio: 1.81, P<0.001) and expected to fail in obtaining emergency funds (adjusted odds ratio: 4.03, P<0.001). In moving forward with their reforms, GCC countries should adopt a financing strategy that addresses the health needs of poorer groups in their pursuit of universal health coverage. Copyright © 2017 Elsevier B.V. All rights reserved.

Monitoring progress towards universal health coverage at country and global levels.

PubMed

Boerma, Ties; Eozenou, Patrick; Evans, David; Evans, Tim; Kieny, Marie-Paule; Wagstaff, Adam

2014-09-01

Universal health coverage (UHC) has been defined as the desired outcome of health system performance whereby all people who need health services (promotion, prevention, treatment, rehabilitation, and palliation) receive them, without undue financial hardship. UHC has two interrelated components: the full spectrum of good-quality, essential health services according to need, and protection from financial hardship, including possible impoverishment, due to out-of-pocket payments for health services. Both components should benefit the entire population. This paper summarizes the findings from 13 country case studies and five technical reviews, which were conducted as part of the development of a global framework for monitoring progress towards UHC. The case studies show the relevance and feasibility of focusing UHC monitoring on two discrete components of health system performance: levels of coverage with health services and financial protection, with a focus on equity. These components link directly to the definition of UHC and measure the direct results of strategies and policies for UHC. The studies also show how UHC monitoring can be fully embedded in often existing, regular overall monitoring of health sector progress and performance. Several methodological and practical issues related to the monitoring of coverage of essential health services, financial protection, and equity, are highlighted. Addressing the gaps in the availability and quality of data required for monitoring progress towards UHC is critical in most countries.

Perceptions of the usefulness of external support to immunization coverage in Guinea-Bissau: a Delphi analysis of the GAVI-Alliance cash-based support.

PubMed

Ferrinho, Paulo; Dramé, Mohamed; Biai, Sidu; Lopes, Orlando; Sousa, Fernando de; Van Lerberghe, Wim

2013-01-01

Although many countries have improved vaccination coverage in recent years, some, including Guinea-Bissau, failed to meet expected targets. This paper tries to understand the main barriers to better vaccination coverage in the context of the GAVI-Alliance (The Global Alliance for Vaccines and Immunisation) cash-based support provided to Guinea-Bissau. The analysis is based on a document analysis and a three round Delphi study with a final consensus meeting. Consensus attributed about 25% of the failure to perform better to implementation problems; and about 10% to governance and also 10% to scarce resources. The qualitative analysis validates the importance of implementation issues and upgraded the relevance of the human resources crisis as an important drawback. The recommendations were balanced in their upstream-downstream focus but were blind to health information issues and logistical difficulties. It is commendable that such a fragile state, with all sorts of barriers, manages to sustain a slow steady growth of its vaccination coverage. Not reaching the targets set reflects the inappropriateness of those targets rather than a lack of commitment of the health workforce. In the unstable context of countries such as Guinea-Bissau, the predictability of the funds from global health initiatives like the GAVI-Alliance seem to make all the difference in achieving small consistent health gains even in the presence of other major bottlenecks.

Monitoring Progress towards Universal Health Coverage at Country and Global Levels

PubMed Central

Boerma, Ties; Eozenou, Patrick; Evans, David; Evans, Tim; Kieny, Marie-Paule; Wagstaff, Adam

2014-01-01

Universal health coverage (UHC) has been defined as the desired outcome of health system performance whereby all people who need health services (promotion, prevention, treatment, rehabilitation, and palliation) receive them, without undue financial hardship. UHC has two interrelated components: the full spectrum of good-quality, essential health services according to need, and protection from financial hardship, including possible impoverishment, due to out-of-pocket payments for health services. Both components should benefit the entire population. This paper summarizes the findings from 13 country case studies and five technical reviews, which were conducted as part of the development of a global framework for monitoring progress towards UHC. The case studies show the relevance and feasibility of focusing UHC monitoring on two discrete components of health system performance: levels of coverage with health services and financial protection, with a focus on equity. These components link directly to the definition of UHC and measure the direct results of strategies and policies for UHC. The studies also show how UHC monitoring can be fully embedded in often existing, regular overall monitoring of health sector progress and performance. Several methodological and practical issues related to the monitoring of coverage of essential health services, financial protection, and equity, are highlighted. Addressing the gaps in the availability and quality of data required for monitoring progress towards UHC is critical in most countries. PMID:25243899

Countdown to 2015 and beyond: fulfilling the health agenda for women and children.

PubMed

Requejo, Jennifer Harris; Bryce, Jennifer; Barros, Aluisio J D; Berman, Peter; Bhutta, Zulfiqar; Chopra, Mickey; Daelmans, Bernadette; de Francisco, Andres; Lawn, Joy; Maliqi, Blerta; Mason, Elizabeth; Newby, Holly; Presern, Carole; Starrs, Ann; Victora, Cesar G

2015-01-31

The end of 2015 will signal the end of the Millennium Development Goal era, when the world can take stock of what has been achieved. The Countdown to 2015 for Maternal, Newborn, and Child Survival (Countdown) has focused its 2014 report on how much has been achieved in intervention coverage in these groups, and on how best to sustain, focus, and intensify efforts to progress for this and future generations. Our 2014 results show unfinished business in achievement of high, sustained, and equitable coverage of essential interventions. Progress has accelerated in the past decade in most Countdown countries, suggesting that further gains are possible with intensified actions. Some of the greatest coverage gaps are in family planning, interventions addressing newborn mortality, and case management of childhood diseases. Although inequities are pervasive, country successes in reaching of the poorest populations provide lessons for other countries to follow. As we transition to the next set of global goals, we must remember the centrality of data to accountability, and the importance of support of country capacity to collect and use high-quality data on intervention coverage and inequities for decision making. To fulfill the health agenda for women and children both now and beyond 2015 requires continued monitoring of country and global progress; Countdown is committed to playing its part in this effort. Copyright © 2015 Elsevier Ltd. All rights reserved.

Petascale Diagnostic Assessment of the Global Portfolio Rainfall Space Missions' Ability to Support Flood Forecasting

NASA Astrophysics Data System (ADS)

Reed, P. M.; Chaney, N.; Herman, J. D.; Wood, E. F.; Ferringer, M. P.

2015-12-01

This research represents a multi-institutional collaboration between Cornell University, The Aerospace Corporation, and Princeton University that has completed a Petascale diagnostic assessment of the current 10 satellite missions providing rainfall observations. Our diagnostic assessment has required four core tasks: (1) formally linking high-resolution astrodynamics design and coordination of space assets with their global hydrological impacts within a Petascale "many-objective" global optimization framework, (2) developing a baseline diagnostic evaluation of a 1-degree resolution global implementation of the Variable Infiltration Capacity (VIC) model to establish the required satellite observation frequencies and coverage to maintain acceptable global flood forecasts, (3) evaluating the limitations and vulnerabilities of the full suite of current satellite precipitation missions including the recently approved Global Precipitation Measurement (GPM) mission, and (4) conceptualizing the next generation spaced-based platforms for water cycle observation. Our team exploited over 100 Million hours of computing access on the 700,000+ core Blue Waters machine to radically advance our ability to discover and visualize key system tradeoffs and sensitivities. This project represents to our knowledge the first attempt to develop a 10,000 member Monte Carlo global hydrologic simulation at one degree resolution that characterizes the uncertain effects of changing the available frequencies of satellite precipitation on drought and flood forecasts. The simulation—optimization components of the work have set a theoretical baseline for the best possible frequencies and coverages for global precipitation given unlimited investment, broad international coordination in reconfiguring existing assets, and new satellite constellation design objectives informed directly by key global hydrologic forecasting requirements. Our research poses a step towards realizing the integrated global water cycle observatory long sought by the World Climate Research Programme, which has to date eluded the world's space agencies.

Routine Vaccination Coverage in Northern Nigeria: Results from 40 District-Level Cluster Surveys, 2014-2015

PubMed Central

Ogbuanu, Ikechukwu U.; Adegoke, Oluwasegun J.; Scobie, Heather M.; Uba, Belinda V.; Wannemuehler, Kathleen A.; Ruiz, Alicia; Elmousaad, Hashim; Ohuabunwo, Chima J.; Mustafa, Mahmud; Nguku, Patrick; Waziri, Ndadilnasiya Endie; Vertefeuille, John F.

2016-01-01

Background Despite recent success towards controlling poliovirus transmission, Nigeria has struggled to achieve uniformly high routine vaccination coverage. A lack of reliable vaccination coverage data at the operational level makes it challenging to target program improvement. To reliably estimate vaccination coverage, we conducted district-level vaccine coverage surveys using a pre-existing infrastructure of polio technical staff in northern Nigeria. Methods Household-level cluster surveys were conducted in 40 polio high risk districts of Nigeria during 2014–2015. Global positioning system technology and intensive supervision by a pool of qualified technical staff were used to ensure high survey quality. Vaccination status of children aged 12–23 months was documented based on vaccination card or caretaker’s recall. District-level coverage estimates were calculated using survey methods. Results Data from 7,815 children across 40 districts were analyzed. District-level coverage with the third dose of diphtheria-pertussis-tetanus vaccine (DPT3) ranged widely from 1–63%, with all districts having DPT3 coverage below the target of 80%. Median coverage across all districts for each of eight vaccine doses (1 Bacille Calmette-Guérin dose, 3 DPT doses, 3 oral poliovirus vaccine doses, and 1 measles vaccine dose) was <50%. DPT3 coverage by survey was substantially lower (range: 28%–139%) than the 2013 administrative coverage reported among children aged <12 months. Common reported reasons for non-vaccination included lack of knowledge about vaccines and vaccination services (50%) and factors related to access to routine immunization services (15%). Conclusions Survey results highlighted vaccine coverage gaps that were systematically underestimated by administrative reporting across 40 polio high risk districts in northern Nigeria. Given the limitations of administrative coverage data, our approach to conducting quality district-level coverage surveys and providing data to assess and remediate issues contributing to poor vaccination coverage could serve as an example in countries with sub-optimal vaccination coverage, similar to Nigeria. PMID:27936077

Routine Vaccination Coverage in Northern Nigeria: Results from 40 District-Level Cluster Surveys, 2014-2015.

PubMed

Gunnala, Rajni; Ogbuanu, Ikechukwu U; Adegoke, Oluwasegun J; Scobie, Heather M; Uba, Belinda V; Wannemuehler, Kathleen A; Ruiz, Alicia; Elmousaad, Hashim; Ohuabunwo, Chima J; Mustafa, Mahmud; Nguku, Patrick; Waziri, Ndadilnasiya Endie; Vertefeuille, John F

2016-01-01

Despite recent success towards controlling poliovirus transmission, Nigeria has struggled to achieve uniformly high routine vaccination coverage. A lack of reliable vaccination coverage data at the operational level makes it challenging to target program improvement. To reliably estimate vaccination coverage, we conducted district-level vaccine coverage surveys using a pre-existing infrastructure of polio technical staff in northern Nigeria. Household-level cluster surveys were conducted in 40 polio high risk districts of Nigeria during 2014-2015. Global positioning system technology and intensive supervision by a pool of qualified technical staff were used to ensure high survey quality. Vaccination status of children aged 12-23 months was documented based on vaccination card or caretaker's recall. District-level coverage estimates were calculated using survey methods. Data from 7,815 children across 40 districts were analyzed. District-level coverage with the third dose of diphtheria-pertussis-tetanus vaccine (DPT3) ranged widely from 1-63%, with all districts having DPT3 coverage below the target of 80%. Median coverage across all districts for each of eight vaccine doses (1 Bacille Calmette-Guérin dose, 3 DPT doses, 3 oral poliovirus vaccine doses, and 1 measles vaccine dose) was <50%. DPT3 coverage by survey was substantially lower (range: 28%-139%) than the 2013 administrative coverage reported among children aged <12 months. Common reported reasons for non-vaccination included lack of knowledge about vaccines and vaccination services (50%) and factors related to access to routine immunization services (15%). Survey results highlighted vaccine coverage gaps that were systematically underestimated by administrative reporting across 40 polio high risk districts in northern Nigeria. Given the limitations of administrative coverage data, our approach to conducting quality district-level coverage surveys and providing data to assess and remediate issues contributing to poor vaccination coverage could serve as an example in countries with sub-optimal vaccination coverage, similar to Nigeria.

New Mission to Measure Global Lightning from the International Space Station (ISS)

NASA Astrophysics Data System (ADS)

Blakeslee, R. J.; Christian, H. J., Jr.; Mach, D. M.; Buechler, D. E.; Koshak, W. J.; Walker, T. D.; Bateman, M. G.; Stewart, M. F.; O'Brien, S.; Wilson, T. O.; Pavelitz, S. D.; Coker, C.

2015-12-01

Over the past 20 years, the NASA Marshall Space Flight Center, the University of Alabama in Huntsville, and their partners developed and demonstrated the effectiveness and value of space-based lightning observations as a remote sensing tool for Earth science research and applications, and, in the process, established a robust global lightning climatology. The observations included measurements from the Lightning Imaging Sensor (LIS) on the Tropical Rainfall Measuring Mission (TRMM) that acquired global observations of total lightning (i.e., intracloud and cloud-to-ground discharges) from November 1997 to April 2015 between 38° N/S latitudes, and its Optical Transient Detector predecessor that acquired observation from May 1995 to April 2000 over 75° N/S latitudes. In February 2016, as an exciting follow-on to these prior missions, a space-qualified LIS built as a flight-spare for TRMM will be delivered to the International Space Station (ISS) for a 2 year or longer mission, flown as a hosted payload on the Department of Defense Space Test Program-Houston 5 (STP-H5) mission. The LIS on ISS will continue observations of the amount, rate, and radiant energy of total lightning over the Earth. More specifically, LIS measures lightning during both day and night, with storm scale resolution (~4 km), millisecond timing, and high, uniform detection efficiency, without any land-ocean bias. Lightning is a direct and most impressive response to intense atmospheric convection. ISS LIS lightning observations will continue to provide important gap-filling inputs to pressing Earth system science issues across a broad range of disciplines. This mission will also extend TRMM time series observations, expand the latitudinal coverage to 54° latitude, provide real-time lightning data to operational users, espically over data sparse oceanic regions, and enable cross-sensor observations and calibrations that includes the new GOES-R Geostationary Lightning Mapper (GLM) and the Meteosat Third Generation Lightning Imager (MTG LI). The ISS platform will also uniquely enable LIS to provide simultaneous and complementary observations with other ISS payloads such as the European Space Agency's Atmosphere-Space Interaction Monitor (ASIM) exploring the connection between lightning and terrestrial gamma-ray flashes (TGFs).

From One Pixel to One Earth: Building a Living Atlas in the Cloud to Analyze and Monitor Global Patterns

NASA Astrophysics Data System (ADS)

Moody, D.; Brumby, S. P.; Chartrand, R.; Franco, E.; Keisler, R.; Kelton, T.; Kontgis, C.; Mathis, M.; Raleigh, D.; Rudelis, X.; Skillman, S.; Warren, M. S.; Longbotham, N.

2016-12-01

The recent computing performance revolution has driven improvements in sensor, communication, and storage technology. Historical, multi-decadal remote sensing datasets at the petabyte scale are now available in commercial clouds, with new satellite constellations generating petabytes per year of high-resolution imagery with daily global coverage. Cloud computing and storage, combined with recent advances in machine learning and open software, are enabling understanding of the world at an unprecedented scale and detail. We have assembled all available satellite imagery from the USGS Landsat, NASA MODIS, and ESA Sentinel programs, as well as commercial PlanetScope and RapidEye imagery, and have analyzed over 2.8 quadrillion multispectral pixels. We leveraged the commercial cloud to generate a tiled, spatio-temporal mosaic of the Earth for fast iteration and development of new algorithms combining analysis techniques from remote sensing, machine learning, and scalable compute infrastructure. Our data platform enables processing at petabytes per day rates using multi-source data to produce calibrated, georeferenced imagery stacks at desired points in time and space that can be used for pixel level or global scale analysis. We demonstrate our data platform capability by using the European Space Agency's (ESA) published 2006 and 2009 GlobCover 20+ category label maps to train and test a Land Cover Land Use (LCLU) classifier, and generate current self-consistent LCLU maps in Brazil. We train a standard classifier on 2006 GlobCover categories using temporal imagery stacks, and we validate our results on co-registered 2009 Globcover LCLU maps and 2009 imagery. We then extend the derived LCLU model to current imagery stacks to generate an updated, in-season label map. Changes in LCLU labels can now be seamlessly monitored for a given location across the years in order to track, for example, cropland expansion, forest growth, and urban developments. An example of change monitoring is illustrated in the included figure showing rainfed cropland change in the Mato Grosso region of Brazil between 2006 and 2009.

Acta Dermatovenerologica Alpina, Pannonica et Adriatica accepted for coverage in Thomson Reuters' Emerging Sources Citation Index (ESCI).

PubMed

Poljak, Mario; Miljković, Jovan; Triglav, Tina

2016-09-01

Acta Dermatovenerologica Alpina, Pannonica et Adriatica (Acta Dermatovenerol APA) is the leading journal in dermatology and sexually transmitted infections in the region. Several important steps were taken during the last 25 years to improve the journal's quality, global visibility, and international impact. After a 1-year trial period, Thomson Reuters recently informed the editorial office that they had accepted Acta Dermatovenerol APA for coverage in Thomson Reuters' new index in the Web of Science Core Collection called the Emerging Sources Citation Index (ESCI). The coverage of Acta Dermatovenerol APA begins with the journal content published online in 2016; that is, from volume 25 onwards.

cMOOCs and Global Learning: An Authentic Alternative

ERIC Educational Resources Information Center

Yeager, Carol; Hurley-Dasgupta, Betty; Bliss, Catherine A.

2013-01-01

Massive open online courses (MOOCs) continue to attract press coverage as they change almost daily in their format, number of registrations, and potential for credentialing. An enticing aspect of the MOOC is its global reach. In this paper, we will focus on a type of MOOC called a cMOOC because it is based on the theory of connectivism and fits…

Can a sample of Landsat sensor scenes reliably estimate the global extent of tropical deforestation?

Treesearch

R. L. Czaplewski

2003-01-01

Tucker and Townshend (2000) conclude that wall-to-wall coverage is needed to avoid gross errors in estimations of deforestation rates' because tropical deforestation is concentrated along roads and rivers. They specifically question the reliability of the 10% sample of Landsat sensor scenes used in the global remote sensing survey conducted by the Food and...

A Coupled GCM-Cloud Resolving Modeling System, and a Regional Scale Model to Study Precipitation Processes

NASA Technical Reports Server (NTRS)

Tao, Wei-Kuo

2006-01-01

Recent GEWEX Cloud System Study (GCSS) model comparison projects have indicated that cloud-resolving models (CRMs) agree with observations better than traditional single-column models in simulating various types of clouds and cloud systems from different geographic locations. Current and future NASA satellite programs can provide cloud, precipitation, aerosol and other data at very fine spatial and temporal scales. It requires a coupled global circulation model (GCM) and cloud-scale model (termed a super-parameterization or multi-scale modeling framework, MMF) to use these satellite data to improve the understanding of the physical processes that are responsible for the variation in global and regional climate and hydrological systems. The use of a GCM will enable global coverage, and the use of a CRM will allow for better and more sophisticated physical parameterization. NASA satellite and field campaign cloud related datasets can provide initial conditions as well as validation for both the MMF and CFWs. The Goddard MMF is based on the 2D Goddard Cumulus Ensemble (GCE) model and the Goddard finite volume general circulation model (fvGCM), and it has started production runs with two years results (1 998 and 1999). In this talk, I will present: (1) A brief review on GCE model and its applications on precipitation processes (microphysical and land processes), (2) The Goddard MMF and the major difference between two existing MMFs (CSU MMF and Goddard MMF), and preliminary results (the comparison with traditional GCMs), and (3) A discussion on the Goddard WRF version (its developments and applications).

QuantFusion: Novel Unified Methodology for Enhanced Coverage and Precision in Quantifying Global Proteomic Changes in Whole Tissues.

PubMed

Gunawardena, Harsha P; O'Brien, Jonathon; Wrobel, John A; Xie, Ling; Davies, Sherri R; Li, Shunqiang; Ellis, Matthew J; Qaqish, Bahjat F; Chen, Xian

2016-02-01

Single quantitative platforms such as label-based or label-free quantitation (LFQ) present compromises in accuracy, precision, protein sequence coverage, and speed of quantifiable proteomic measurements. To maximize the quantitative precision and the number of quantifiable proteins or the quantifiable coverage of tissue proteomes, we have developed a unified approach, termed QuantFusion, that combines the quantitative ratios of all peptides measured by both LFQ and label-based methodologies. Here, we demonstrate the use of QuantFusion in determining the proteins differentially expressed in a pair of patient-derived tumor xenografts (PDXs) representing two major breast cancer (BC) subtypes, basal and luminal. Label-based in-spectra quantitative peptides derived from amino acid-coded tagging (AACT, also known as SILAC) of a non-malignant mammary cell line were uniformly added to each xenograft with a constant predefined ratio, from which Ratio-of-Ratio estimates were obtained for the label-free peptides paired with AACT peptides in each PDX tumor. A mixed model statistical analysis was used to determine global differential protein expression by combining complementary quantifiable peptide ratios measured by LFQ and Ratio-of-Ratios, respectively. With minimum number of replicates required for obtaining the statistically significant ratios, QuantFusion uses the distinct mechanisms to "rescue" the missing data inherent to both LFQ and label-based quantitation. Combined quantifiable peptide data from both quantitative schemes increased the overall number of peptide level measurements and protein level estimates. In our analysis of the PDX tumor proteomes, QuantFusion increased the number of distinct peptide ratios by 65%, representing differentially expressed proteins between the BC subtypes. This quantifiable coverage improvement, in turn, not only increased the number of measurable protein fold-changes by 8% but also increased the average precision of quantitative estimates by 181% so that some BC subtypically expressed proteins were rescued by QuantFusion. Thus, incorporating data from multiple quantitative approaches while accounting for measurement variability at both the peptide and global protein levels make QuantFusion unique for obtaining increased coverage and quantitative precision for tissue proteomes. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

Graph-based optimization of epitope coverage for vaccine antigen design

DOE PAGES

Theiler, James Patrick; Korber, Bette Tina Marie

2017-01-29

Epigraph is a recently developed algorithm that enables the computationally efficient design of single or multi-antigen vaccines to maximize the potential epitope coverage for a diverse pathogen population. Potential epitopes are defined as short contiguous stretches of proteins, comparable in length to T-cell epitopes. This optimal coverage problem can be formulated in terms of a directed graph, with candidate antigens represented as paths that traverse this graph. Epigraph protein sequences can also be used as the basis for designing peptides for experimental evaluation of immune responses in natural infections to highly variable proteins. The epigraph tool suite also enables rapidmore » characterization of populations of diverse sequences from an immunological perspective. Fundamental distance measures are based on immunologically relevant shared potential epitope frequencies, rather than simple Hamming or phylogenetic distances. Here, we provide a mathematical description of the epigraph algorithm, include a comparison of different heuristics that can be used when graphs are not acyclic, and we describe an additional tool we have added to the web-based epigraph tool suite that provides frequency summaries of all distinct potential epitopes in a population. Lastly, we also show examples of the graphical output and summary tables that can be generated using the epigraph tool suite and explain their content and applications.« less

Graph-based optimization of epitope coverage for vaccine antigen design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Theiler, James Patrick; Korber, Bette Tina Marie

Epigraph is a recently developed algorithm that enables the computationally efficient design of single or multi-antigen vaccines to maximize the potential epitope coverage for a diverse pathogen population. Potential epitopes are defined as short contiguous stretches of proteins, comparable in length to T-cell epitopes. This optimal coverage problem can be formulated in terms of a directed graph, with candidate antigens represented as paths that traverse this graph. Epigraph protein sequences can also be used as the basis for designing peptides for experimental evaluation of immune responses in natural infections to highly variable proteins. The epigraph tool suite also enables rapidmore » characterization of populations of diverse sequences from an immunological perspective. Fundamental distance measures are based on immunologically relevant shared potential epitope frequencies, rather than simple Hamming or phylogenetic distances. Here, we provide a mathematical description of the epigraph algorithm, include a comparison of different heuristics that can be used when graphs are not acyclic, and we describe an additional tool we have added to the web-based epigraph tool suite that provides frequency summaries of all distinct potential epitopes in a population. Lastly, we also show examples of the graphical output and summary tables that can be generated using the epigraph tool suite and explain their content and applications.« less

How important are peatlands globally in providing drinking water resources?

NASA Astrophysics Data System (ADS)

Xu, Jiren; Morris, Paul; Holden, Joseph

2017-04-01

The potential role of peatlands as water stores and sources of downstream water resources for human use is often cited in publications setting the context for the importance of peatlands, but is rarely backed up with substantive evidence. We sought to determine the global role of peatlands in water resource provision. We developed the Peat Population Index (PPI) that combines the coverage of peat and the local population density to show focused (hotspot) areas where there is a combination of both large areas of peat and large populations who would potentially use water sourced from those peatlands. We also developed a method for estimating the proportion of river water that interacted with contributing peatlands before draining into rivers and reservoirs used as a drinking water resource. The Peat Reservoir Index (PRI) estimates the contribution of peatlands to domestic water use to be 1.64 km3 per year which is 0.35 % of the global total. The results suggest that although peatlands are widespread, the spatial distribution of the high PPI and PRI river basins is concentrated in European middle latitudes particularly around major conurbations in The Netherlands, northern England, Scotland (Glasgow) and Ireland (Dublin), although there were also some important systems in Florida, the Niger Delta and Malaysia. More detailed research into water resource provision in high PPI areas showed that they were not always also high PRI areas as often water resources were delivered to urban centres from non-peat areas, despite a large area of peat within the catchment. However, particularly in the UK and Ireland, there are some high PRI systems where peatlands directly supply water to nearby urban centres. Thus both indices are useful and can be used at a global level while more local refinement enables enhanced use which supports global and local peatland protection measures. We now intend to study the impacts of peatland degradation and climate change on water resource provision in hotspot PPI and PRI regions.

Contributions of national and global health estimates to monitoring health-related sustainable development goals.

PubMed

Bundhamcharoen, Kanitta; Limwattananon, Supon; Kusreesakul, Khanitta; Tangcharoensathien, Viroj

2016-01-01

The millennium development goals triggered an increased demand for data on child and maternal mortalities for monitoring progress. With the advent of the sustainable development goals and growing evidence of an epidemiological transition toward non-communicable diseases, policymakers need data on mortality and disease trends and distribution to inform effective policies and support monitoring progress. Where there are limited capacities to produce national health estimates (NHEs), global health estimates (GHEs) can fill gaps for global monitoring and comparisons. This paper discusses lessons learned from Thailand's burden of disease (BOD) study on capacity development on NHEs and discusses the contributions and limitations of GHEs in informing policies at the country level. Through training and technical support by external partners, capacities are gradually strengthened and institutionalized to enable regular updates of BOD at national and subnational levels. Initially, the quality of cause-of-death reporting in death certificates was inadequate, especially for deaths occurring in the community. Verbal autopsies were conducted, using domestic resources, to determine probable causes of deaths occurring in the community. This method helped to improve the estimation of years of life lost. Since the achievement of universal health coverage in 2002, the quality of clinical data on morbidities has also considerably improved. There are significant discrepancies between the Global Burden of Disease 2010 study estimates for Thailand and the 1999 nationally generated BOD, especially for years of life lost due to HIV/AIDS, and the ranking of priority diseases. National ownership of NHEs and an effective interface between researchers and decision-makers contribute to enhanced country policy responses, whereas subnational data are intended to be used by various subnational partners. Although GHEs contribute to benchmarking country achievement compared with global health commitments, they may hamper development of NHE capacities. GHEs should encourage and support countries to improve their data systems and develop a data infrastructure that supports the production of empirical data needed to underpin estimation efforts.

Contributions of national and global health estimates to monitoring health-related Sustainable Development Goals in Thailand.

PubMed

Bundhamcharoen, Kanitta; Limwattananon, Supon; Kusreesakul, Khanitta; Tangcharoensathien, Viroj

2017-01-01

The Millennium Development Goals (MDGs) triggered increased demand for data on child and maternal mortality for monitoring progress. With the advent of the Sustainable Development Goals (SDGs) and growing evidence of an epidemiological transition towards non-communicable diseases, policy makers need data on mortality and disease trends and distribution to inform effective policies and support monitoring progress. Where there are limited capacities to produce national health estimates (NHEs), global health estimates (GHEs) can fill gaps for global monitoring and comparisons. This paper draws lessons learned from Thailand's burden of disease study (BOD) on capacity development for NHEs, and discusses the contributions and limitation of GHEs in informing policies at country level. Through training and technical support by external partners, capacities are gradually strengthened and institutionalized to enable regular updates of BOD at national and sub-national levels. Initially, the quality of cause of death reporting in the death certificates was inadequate, especially for deaths occurring in the community. Verbal autopsies were conducted, using domestic resources, to determine probable causes of deaths occurring in the community. This helped improve the estimation of years of life lost. Since the achievement of universal health coverage in 2002, the quality of clinical data on morbidities has also considerably improved. There are significant discrepancies between the 2010 Global Burden of Diseases (GBD) estimates for Thailand and the 1999 nationally generated BOD, especially for years of life lost due to HIV/AIDS, and the ranking of priority diseases. National ownership of NHEs and effective interfaces between researchers and decision makers contribute to enhanced country policy responses, while sub-national data are intended to be used by various sub-national-level partners. Though GHEs contribute to benchmarking country achievement compared with global health commitments, they may hamper development of NHE capacities. GHEs should encourage and support countries to improve their data systems and develop a data infrastructure that supports the production of empirical data needed to underpin estimation efforts.

Global Albedo Variations on Mars from Recent MRO/MARCI and Other Space-Based Observations

NASA Astrophysics Data System (ADS)

Bell, J. F., III; Wellington, D. F.

2017-12-01

Dramatic changes in Mars surface albedo have been quantified by telescopic, orbital, and surface-based observations over the last 40 years. These changes provide important inputs for global and mesoscale climate models, enabling characterization of seasonal and secular variations in the distribution of mobile surface materials (dust, sand) in the planet's current climate regime. Much of the modern record of dust storms and albedo changes comes from synoptic-scale global imaging from the Viking Orbiter, Mars Global Surveyor (MGS), Hubble Space Telescope (HST), and Mars Reconnaissance Orbiter (MRO) missions, as well as local-scale observations from long-lived surface platforms like the Spirit and Opportunity rovers. Here we focus on the substantial time history of global-scale images acquired from the MRO Mars Color Imager (MARCI). MARCI is a wide-angle multispectral imager that acquires daily coverage of most of the surface at up to 1 km/pixel. MARCI has been in orbit since 2006, providing six Mars years of continuous surface and atmospheric observations, and building on the nearly five previous Mars years of global-scale imaging from the MGS Mars Orbiter Camera Wide Angle (MOC/WA) imager, which operated from 1997 to 2006. While many of the most significant MARCI-observed changes in the surface albedo are the result of large dust storms, other regions experience seasonal darkening events that repeat with different degrees of annual regularity. Some of these are associated with local dust storms, while for others, frequent surface changes take place with no associated evidence for dust storms, suggesting action by seasonally-variable winds and/or small-scale storms/dust devils too small to resolve. Discrete areas of dramatic surface changes across widely separated regions of Tharsis and in portions of Solis Lacus and Syrtis Major are among the regions where surface changes have been observed without a direct association to specific detectable dust storm events. Deposition following the annual southern summer dusty season plays a significant role in maintaining the cyclic nature of these changes. These and other historical observations also show that major regional or global-scale dust storms produce unique changes that may require several Mars years to reverse.

Big Data and High-Performance Computing in Global Seismology

NASA Astrophysics Data System (ADS)

Bozdag, Ebru; Lefebvre, Matthieu; Lei, Wenjie; Peter, Daniel; Smith, James; Komatitsch, Dimitri; Tromp, Jeroen

2014-05-01

Much of our knowledge of Earth's interior is based on seismic observations and measurements. Adjoint methods provide an efficient way of incorporating 3D full wave propagation in iterative seismic inversions to enhance tomographic images and thus our understanding of processes taking place inside the Earth. Our aim is to take adjoint tomography, which has been successfully applied to regional and continental scale problems, further to image the entire planet. This is one of the extreme imaging challenges in seismology, mainly due to the intense computational requirements and vast amount of high-quality seismic data that can potentially be assimilated. We have started low-resolution inversions (T > 30 s and T > 60 s for body and surface waves, respectively) with a limited data set (253 carefully selected earthquakes and seismic data from permanent and temporary networks) on Oak Ridge National Laboratory's Cray XK7 "Titan" system. Recent improvements in our 3D global wave propagation solvers, such as a GPU version of the SPECFEM3D_GLOBE package, will enable us perform higher-resolution (T > 9 s) and longer duration (~180 m) simulations to take the advantage of high-frequency body waves and major-arc surface waves, thereby improving imbalanced ray coverage as a result of the uneven global distribution of sources and receivers. Our ultimate goal is to use all earthquakes in the global CMT catalogue within the magnitude range of our interest and data from all available seismic networks. To take the full advantage of computational resources, we need a solid framework to manage big data sets during numerical simulations, pre-processing (i.e., data requests and quality checks, processing data, window selection, etc.) and post-processing (i.e., pre-conditioning and smoothing kernels, etc.). We address the bottlenecks in our global seismic workflow, which are mainly coming from heavy I/O traffic during simulations and the pre- and post-processing stages, by defining new data formats for seismograms and outputs of our 3D solvers (i.e., meshes, kernels, seismic models, etc.) based on ORNL's ADIOS libraries. We will discuss our global adjoint tomography workflow on HPC systems as well as the current status of our global inversions.

Unesco's Global Ethics Observatory

PubMed Central

Have, H ten; Ang, T W

2007-01-01

The Global Ethics Observatory, launched by the United Nations Educational, Scientific, and Cultural Organization in December 2005, is a system of databases in the ethics of science and technology. It presents data on experts in ethics, on institutions (university departments and centres, commissions, councils and review boards, and societies and associations) and on teaching programmes in ethics. It has a global coverage and will be available in six major languages. Its aim is to facilitate the establishment of ethical infrastructures and international cooperation all around the world. PMID:17209103

Project Catch: A space based solution to combat illegal, unreported and unregulated fishing. Part I: Vessel monitoring system

NASA Astrophysics Data System (ADS)

Detsis, Emmanouil; Brodsky, Yuval; Knudtson, Peter; Cuba, Manuel; Fuqua, Heidi; Szalai, Bianca

2012-11-01

Space assets have a unique opportunity to play a more active role in global resource management. There is a clear need to develop resource management tools in a global framework. Illegal, Unregulated and Unreported (IUU) fishing is placing pressure on the health and size of fishing stocks around the world. Earth observation systems can provide fishery management organizations with cost effective monitoring of large swaths of ocean. Project Catch is a fisheries management project based upon the complimentary, but independent Catch-VMS and Catch-GIS systems. Catch-VMS is a Vessel Monitoring System with increased fidelity over existing offerings. Catch-GIS is a Geographical Information System that combines VMS information with existing Earth Observation data and other data sources to identify Illegal, Unregulated and Unreported (IUU) fishing. Project Catch was undertaken by 19 Masters students from the 2010 class of the International Space University. In this paper, the space-based system architecture of Project Catch is presented and analyzed. The rationale for the creation of the system, as well as the engineering trade-off studies in its creation, are discussed. The Catch-VMS proposal was envisaged in order to address two specific problems: (1) the expansion of illegal fishing to high-latitude regions where existing satellite systems coverage is an issue and (2) the lack of coverage in remote oceanic regions due to reliance on coastal-based monitoring. Catch-VMS utilizes ship-borne transponders and hosted-payload receivers on a Global Navigation Satellite System in order to monitor the position and activity of compliant fishing vessels. Coverage is global and continuous with multiple satellites in view providing positional verification through multilateration techniques. The second part of the paper briefly describes the Catch-GIS system and investigates its cost of implementation.

Cloud Coverage and Height Distribution from the GLAS Polar Orbiting Lidar: Comparison to Passive Cloud Retrievals

NASA Technical Reports Server (NTRS)

Spinhime, J. D.; Palm, S. P.; Hlavka, D. L.; Hart, W. D.; Mahesh, A.

2004-01-01

The Geoscience Laser Altimeter System (GLAS) began full on orbit operations in September 2003. A main application of the two-wavelength GLAS lidar is highly accurate detection and profiling of global cloud cover. Initial analysis indicates that cloud and aerosol layers are consistently detected on a global basis to cross-sections down to 10(exp -6) per meter. Images of the lidar data dramatically and accurately show the vertical structure of cloud and aerosol to the limit of signal attenuation. The GLAS lidar has made the most accurate measurement of global cloud coverage and height to date. In addition to the calibrated lidar signal, GLAS data products include multi level boundaries and optical depth of all transmissive layers. Processing includes a multi-variable separation of cloud and aerosol layers. An initial application of the data results is to compare monthly cloud means from several months of GLAS observations in 2003 to existing cloud climatologies from other satellite measurement. In some cases direct comparison to passive cloud retrievals is possible. A limitation of the lidar measurements is nadir only sampling. However monthly means exhibit reasonably good global statistics and coverage results, at other than polar regions, compare well with other measurements but show significant differences in height distribution. For polar regions where passive cloud retrievals are problematic and where orbit track density is greatest, the GLAS results are particularly an advance in cloud cover information. Direct comparison to MODIS retrievals show a better than 90% agreement in cloud detection for daytime, but less than 60% at night. Height retrievals are in much less agreement. GLAS is a part of the NASA EOS project and data products are thus openly available to the science community (see http://glo.gsfc.nasa.gov).

What did the Go4Health policy research project contribute to the policy discourse on the sustainable development goals? A reflexive review.

PubMed

Te, Vannarath; Floden, Nadia; Hussain, Sameera; Brolan, Claire E; Hill, Peter S

2018-05-16

In 2012, the European Commission funded Go4Health-Goals and Governance for Global Health, a consortium of 13 academic research and human rights institutions from both Global North and South-to track the evolution of the Sustainable Development Goals (SDGs), and provide ongoing policy advice. This paper reviews the research outputs published between 2012 and 2016, analyzing the thematic content of the publications, and the influence on global health and development discourse through citation metrics. Analysis of the 54 published papers showed 6 dominant themes related to the SDGs: the formulation process for the SDG health goal; the right to health; Universal Health Coverage; voices of marginalized peoples; global health governance; and the integration of health across the other SDGs. The papers combined advocacy---particularly for the right to health and its potential embodiment in Universal Health Coverage-with qualitative research and analysis of policy and stakeholders. Go4Health's publications on the right to health, global health governance and the voices of marginalized peoples in relation to the SDGs represented a substantial proportion of papers published for these topics. Go4Health analysis of the right to health clarified its elements and their application to Universal Health Coverage, global health governance, financing the SDGs and access to medicines. Qualitative research identified correspondence between perceptions of marginalized peoples and right to health principles, and reluctance among multilateral organizations to explicitly represent the right to health in the goals, despite their acknowledgement of their importance. Citation metrics analysis confirmed an average of 5.5 citations per paper, with a field-weighted citation impact of 2.24 for the 43 peer reviewed publications. Citations in the academic literature and UN policy documents confirmed the impact of Go4Health on the global discourse around the SDGs, but within the Go4Health consortium there was also evidence of two epistemological frames of analysis-normative legal analysis and empirical research-that created productive synergies in unpacking the health SDG and the right to health. The analysis offers clear evidence for the contribution of funded programmatic research-such as the Go4Health project-to the global health discourse.

How much does it cost to achieve coverage targets for primary healthcare services? A costing model from Aceh, Indonesia.

PubMed

Abdullah, Asnawi; Hort, Krishna; Abidin, Azwar Zaenal; Amin, Fadilah M

2012-01-01

Despite significant investment in improving service infrastructure and training of staff, public primary healthcare services in low-income and middle-income countries tend to perform poorly in reaching coverage targets. One of the factors identified in Aceh, Indonesia was the lack of operational funds for service provision. The objective of this study was to develop a simple and transparent costing tool that enables health planners to calculate the unit costs of providing basic health services to estimate additional budgets required to deliver services in accordance with national targets. The tool was developed using a standard economic approach that linked the input activities to achieving six national priority programs at primary healthcare level: health promotion, sanitation and environment health, maternal and child health and family planning, nutrition, immunization and communicable diseases control, and treatment of common illness. Costing was focused on costs of delivery of the programs that need to be funded by local government budgets. The costing tool consisting of 16 linked Microsoft Excel worksheets was developed and tested in several districts enabled the calculation of the unit costs of delivering of the six national priority programs per coverage target of each program (such as unit costs of delivering of maternal and child health program per pregnant mother). This costing tool can be used by health planners to estimate additional money required to achieve a certain level of coverage of programs, and it can be adjusted for different costs and program delivery parameters in different settings. Copyright © 2012 John Wiley & Sons, Ltd.

Recent developments and future directions in the monitoring of terrestrial sun-induced chlorophyll fluorescence from space

NASA Astrophysics Data System (ADS)

Guanter, L.

2017-12-01

Sun-induced chlorophyll fluorescence (SIF) is an electromagnetic signal emitted by the chlorophyll-a of assimilating plants in the 650-850 nm spectral range. The SIF emission has a mechanistic link to photosynthesis and responds instantaneously to perturbations in environmental conditions such as light and water stress, which makes it a powerful proxy for plants' photosynthetic activity. Global measurements of SIF from space have been available since late 2011 from four different atmospheric satellite missions (chronologically, GOSAT, SCIAMACHY, GOME-2 and OCO-2). The potential of the derived SIF data sets to represent the photosynthetic activity of different ecosystems, including large crop belts worldwide, the Amazon rainforest and boreal evergreen forests has been demonstrated in the relatively short life-time of global SIF data. Despite the demonstrated potential of SIF data as a proxy for global terrestrial gross primary production, current observations are partly hampered by a coarse spatial resolution or the lack of spatial coverage. For this reason, great expectations are put on the upcoming TROPOMI instrument onboard the Copernicus' Sentinel 5-Precursor mission to be launched by mid-end of 2017. TROPOMI will provide daily global coverage with a spatial resolution between 3 and 7 km and continuous spectral coverage of the visible and near-infrared part of the spectrum. The recent selection of FLEX as the ESA Earth Explorer 8 to be launched around 2022 and several upcoming geostationary missions (TEMPO, Sentinel-4 and GeoCARB, covering Europe and the Americas) with potential for SIF retrievals complete an exciting near-future scenario for the monitoring of SIF from space. In this contribution, we will provide an overview of recent developments in the global monitoring of SIF and will introduce the near-future observational scenario with especial emphasis on TROPOMI and the geostationary missions to be launched in the coming years.

Seasonal influenza vaccine dose distribution in 157 countries (2004-2011).

PubMed

Palache, Abraham; Oriol-Mathieu, Valerie; Abelin, Atika; Music, Tamara

2014-11-12

Globally there are an estimated 3-5 million cases of severe influenza illness every year, resulting in 250,000-500,000 deaths. At the World Health Assembly in 2003, World Health Organization (WHO) resolved to increase influenza vaccine coverage rates (VCR) for high-risk groups, particularly focusing on at least 75% of the elderly by 2010. But systematic worldwide data have not been available to assist public health authorities to monitor vaccine uptake and review progress toward vaccination coverage targets. In 2008, the International Federation of Pharmaceutical Manufacturers and Associations Influenza Vaccine Supply task force (IFPMA IVS) developed a survey methodology to assess global influenza vaccine dose distribution. The current survey results represent 2011 data and demonstrate the evolution of the absolute number distributed between 2004 and 2011 inclusive, and the evolution in the per capita doses distributed in 2008-2011. Global distribution of IFPMA IVS member doses increased approximately 86.9% between 2004 and 2011, but only approximately 12.1% between 2008 and 2011. The WHO's regions in Eastern Mediterranean (EMRO), Southeast Asian (SEARO) and Africa (AFRO) together account for about 47% of the global population, but only 3.7% of all IFPMA IVS doses distributed. While distributed doses have globally increased, they have decreased in EURO and EMRO since 2009. Dose distribution can provide a reasonable proxy of vaccine utilization. Based on the dose distribution, we conclude that seasonal influenza VCR in many countries remains well below the WHA's VCR targets and below the recommendations of the Council of the European Union in EURO. Inter- and intra-regional disparities in dose distribution trends call into question the impact of current vaccine recommendations at achieving coverage targets. Additional policy measures, particularly those that influence patients adherence to vaccination programs, such as reimbursement, healthcare provider knowledge, attitudes, practices, and communications, are required for VCR targets to be met and benefit public health. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

Health workers' attitudes, perceptions and knowledge of influenza immunization in Lima, Peru: A mixed methods study.

PubMed

Bazán, Magdalena; Villacorta, Erika; Barbagelatta, Gisella; Jimenez, M Michelle; Goya, Cecilia; Bartolini, Rosario M; Penny, Mary E

2017-05-19

Vaccination against seasonal influenza in health workers is recommended but coverage is variable. This study aimed to determine coverage of influenza vaccination among health workers in Lima, Peru in 2010; explore barriers and enabling elements for vaccination; and suggest strategies to improve coverage. Qualitative interviews informed the development of a survey instrument that consisted of open and close-ended questions. Sub-analyses were done by occupational group and results were calculated as percentages for each possible response with confidence intervals of 95%. Coverage of the influenza vaccination was 77.2%. Vaccinated staff were less likely to have permanent contracts (p=0.0150) and vaccination coverage was lower in physicians (p=0.0001). Over 90% cited protection of themselves, families and patients as reasons for vaccination and 48% mentioned peer encouragement. Fear of adverse events (47%) and organizational barriers (>30%) were reasons for non-vaccination. To improve coverage, highest priority was given to strategies providing more information. Key factors in driving health worker vaccination include desire for protection and peer encouragement. Perceptual barriers based on a misunderstanding of the epidemiology of influenza and vaccination could be overcome by targeted education and information. Organizational barriers require attention to how vaccination is implemented within health facilities. Copyright © 2017 Elsevier Ltd. All rights reserved.

Tunable Signal-Off and Signal-On Electrochemical Cisplatin Sensor.

PubMed

Wu, Yao; Lai, Rebecca Y

2017-09-19

We report the first electrochemical cisplatin sensor fabricated with a thiolated and methylene blue (MB)-modified oligo-adenine (A)-guanine (G) DNA probe. Depending on the probe coverage, the sensor can behave as a signal-off or signal-on sensor. For the high-coverage sensor, formation of intrastrand Pt(II)-AG adducts rigidifies the oligo-AG probe, resulting in a concentration-dependent decrease in the MB signal. For the low-coverage sensor, the increase in probe-to-probe spacing enables binding of cisplatin via the intrastrand GNG motif (N = A), generating a bend in the probe which results in an increase in the MB current. Although both high-coverage signal-off and low-coverage signal-on sensors are capable of detecting cisplatin, the signal-on sensing mechanism is better suited for real time analysis of cisplatin. The low-coverage sensor has a lower limit of detection, wider optimal AC frequency range, and faster response time. It has high specificity for cisplatin and potentially other Pt(II) drugs and does not cross-react with satraplatin, a Pt(IV) prodrug. It is also selective enough to be employed directly in 50% saliva and 50% urine. This detection strategy may offer a new approach for sensitive and real time analysis of cisplatin in clinical samples.

To close the childhood immunization gap, we need a richer understanding of parents' decision-making.

PubMed

Corben, Paul; Leask, Julie

2016-12-01

Vaccination is widely acknowledged as one of the most successful public health interventions globally and in most high-income countries childhood vaccination coverage rates are moderately high. Yet in many instances, immunisation rates remain below aspirational targets and have shown only modest progress toward those targets in recent years, despite concerted efforts to improve uptake. In part, coverage rates reflect individual parents' vaccination attitudes and decisions and, because vaccination decision-making is complex and context-specific, it remains challenging at individual and community levels to assist parents to make positive decisions. Consequently, in the search for opportunities to improve immunisation coverage, there has been a renewed research focus on parents' decision-making. This review provides an overview of the literature surrounding parents' vaccination decision-making, offering suggestions for where efforts to increase vaccination coverage should be targeted and identifying areas for further research.

Experiences and Lessons From Polio Eradication Applied to Immunization in 10 Focus Countries of the Polio Endgame Strategic Plan

PubMed Central

Mallya, Apoorva; Sandhu, Hardeep; Anya, Blanche-Philomene; Yusuf, Nasir; Ntakibirora, Marcelline; Hasman, Andreas; Fahmy, Kamal; Agbor, John; Corkum, Melissa; Sumaili, Kyandindi; Siddique, Anisur Rahman; Bammeke, Jane; Braka, Fiona; Andriamihantanirina, Rija; Ziao, Antoine-Marie C.; Djumo, Clement; Yapi, Moise Desire; Sosler, Stephen; Eggers, Rudolf

2017-01-01

Abstract Nine polio areas of expertise were applied to broader immunization and mother, newborn and child health goals in ten focus countries of the Polio Eradication Endgame Strategic Plan: policy & strategy development, planning, management and oversight (accountability framework), implementation & service delivery, monitoring, communications & community engagement, disease surveillance & data analysis, technical quality & capacity building, and partnerships. Although coverage improvements depend on multiple factors and increased coverage cannot be attributed to the use of polio assets alone, 6 out of the 10 focus countries improved coverage in three doses of diphtheria tetanus pertussis containing vaccine between 2013 and 2015. Government leadership, evidence-based programming, country-driven comprehensive operational annual plans, community partnership and strong accountability systems are critical for all programs and polio eradication has illustrated these can be leveraged to increase immunization coverage and equity and enhance global health security in the focus countries. PMID:28838187

Interactively Browsing NASA's EOS Imagery in Full Resolution

NASA Astrophysics Data System (ADS)

Boller, R. A.; Joshi, T.; Schmaltz, J. E.; Ilavajhala, S.; Davies, D.; Murphy, K. J.

2012-12-01

Worldview is a new tool designed to interactively browse full-resolution imagery from NASA's fleet of Earth Observing System (EOS) satellites. It is web-based and developed using open standards (JavaScript, CSS, HTML) for cross-platform compatibility. It addresses growing user demands for access to full-resolution imagery by providing a responsive, interactive interface with global coverage, no artificial boundaries, and views in geographic and polar projections. Currently tailored to the near real-time community, Worldview enables the rapid evaluation and comparison of imagery related to such application areas as fires, floods, and air quality. It is supported by the Global Imagery Browse Services (GIBS), a system that continuously ingests, mosaics, and serves approximately 21GB of imagery daily. This imagery spans over 50 data products that are available within three hours of observation from instruments aboard Terra, Aqua, and Aura. The GIBS image archive began in May 2012 and will have published approximately 4.4TB of imagery as of December 2012. Worldview facilitates rapid access to this archive and is supplemented by socioeconomic data layers from the Socioeconomic Data and Applications Center (SEDAC), including products such as population density and economic risk from cyclones. Future plans include the accessibility of additional products that cover the entire Terra/MODIS and Aqua/MODIS missions (>150TB) and the ability to download the underlying science data of the onscreen imagery.

Educating and Training a Workforce for Nutrition in a Post-2015 World12

PubMed Central

Fanzo, Jessica C; Graziose, Matthew M; Kraemer, Klaus; Gillespie, Stuart; Johnston, Jessica L; de Pee, Saskia; Monterrosa, Eva; Badham, Jane; Bloem, Martin W; Dangour, Alan D; Deckelbaum, Richard; Dobermann, Achim; Fracassi, Patrizia; Hossain, SM Moazzem; Ingram, John; Jerling, Johann C; Jones, CJ; Jap, Stefanus Indrayana; Kiess, Lynnda; Marshall, Quinn; Martin, Keith; Narayan, Anuradha; Amuyunzu-Nayamongo, Mary; Pepping, Fré; West, Keith P

2015-01-01

Nearly all countries in the world today are burdened with malnutrition, manifesting as undernutrition, micronutrient deficiencies, and/or overweight and obesity. Despite some progress, efforts to alleviate malnutrition are hampered by a shortage in number, skills, and geographic coverage, of a workforce for nutrition. Here, we report the findings of the Castel Gandolfo workshop, a convening of experts from diverse fields in March 2014 to consider how to develop the capacity of a global cadre of nutrition professionals for the post-2015 development era. Workshop participants identified several requirements for developing a workforce for nutrition, including an ability to work as part of a multisectoral team; communication, advocacy, and leadership skills to engage decision makers; and a set of technical skills to address future challenges for nutrition. Other opportunities were highlighted that could immediately contribute to capacity development, including the creation of a consortium to link global North and South universities, online training modules for middle managers, and practical, hands-on experiences for frontline nutrition workers. Institutional and organizational support is needed to enable workshop recommendations on education and training to be effectively implemented and sustained. The findings from the Castel Gandolfo workshop can contribute to the delivery of successful nutrition-relevant actions in the face of mounting external pressures and informing and attaining the forthcoming Sustainable Development Goals. PMID:26567189

The Earth Observing System Terra Mission

NASA Technical Reports Server (NTRS)

Kaufman, Yoram J.; Einaudi, Franco (Technical Monitor)

2000-01-01

Langley's remarkable solar and lunar spectra collected from Mt. Whitney inspired Arrhenius to develop the first quantitative climate model in 1896. After the launch in Dec. 16 1999, NASA's Earth Observing AM Satellite (EOS-Terra) will repeat Langley's experiment, but for the entire planet, thus pioneering a wide array of calibrated spectral observations from space of the Earth System. Conceived in response to real environmental problems, EOS-Terra, in conjunction with other international satellite efforts, will fill a major gap in current efforts by providing quantitative global data sets with a resolution better than 1 km on the physical, chemical and biological elements of the earth system. Thus, like Langley's data, EOS-Terra can revolutionize climate research by inspiring a new generation of climate system models and enable us to assess the human impact on the environment. In the talk I shall review the historical perspective of the Terra mission and the key new elements of the mission. We expect to have first images that demonstrate the most innovative capability from EOS Terra 5 instruments: MODIS - 1.37 micron cirrus cloud channel; 250m daily coverage for clouds and vegetation change; 7 solar channels for land and aerosol studies; new fire channels; Chlorophyll fluorescence; MISR - first 9 multi angle views of clouds and vegetation; MOPITT - first global CO maps and C114 maps; ASTER - Thermal channels for geological studies with 15-90 m resolution.

Fire and Deforestation Dynamics in South America over the Past 50 Years

NASA Astrophysics Data System (ADS)

van Marle, M.; Field, R. D.; van der Werf, G.

2015-12-01

Fires play an important role in the Earth system and are one of the major sources of greenhouse gases and aerosols. Satellites have been key to understand their spatial and temporal variability in space and time, but the most frequently used satellite datasets start only in 1995. There are still large uncertainties about the frequency and intensity of fires in the pre-satellite time period, especially in regions with active deforestation, which may have changed dramatically in intensity in the past decades influencing fire dynamics. We used two datasets to extend the record of fires and deforestation in the Amazon region back in time: 1) annual forest loss rates starting in 1990 derived from Vegetation Optical Depth (VOD), which is a satellite-based vegetation product that can be used as proxy for forest loss, and 2) horizontal visibility as proxy for fire emissions, reported by weather stations and airports in the Amazon, which started around 1940, and having widespread coverage since 1973. We show that these datasets overlap with fire emission estimates from the Global Fire Emissions Database (GFED) enabling us to estimate fire emissions over the last 50 years. We will discuss how fires have varied over time in this region with globally significant emissions, how droughts have influenced fire activity and deforestation rates, and what the impact is of land-use change caused by fire on emissions in the Amazon region.

Educating and training a workforce for nutrition in a post-2015 world.

PubMed

Fanzo, Jessica C; Graziose, Matthew M; Kraemer, Klaus; Gillespie, Stuart; Johnston, Jessica L; de Pee, Saskia; Monterrosa, Eva; Badham, Jane; Bloem, Martin W; Dangour, Alan D; Deckelbaum, Richard; Dobermann, Achim; Fracassi, Patrizia; Hossain, Sm Moazzem; Ingram, John; Jerling, Johann C; Jones, C J; Jap, Stefanus Indrayana; Kiess, Lynnda; Marshall, Quinn; Martin, Keith; Narayan, Anuradha; Amuyunzu-Nayamongo, Mary; Pepping, Fré; West, Keith P

2015-11-01

Nearly all countries in the world today are burdened with malnutrition, manifesting as undernutrition, micronutrient deficiencies, and/or overweight and obesity. Despite some progress, efforts to alleviate malnutrition are hampered by a shortage in number, skills, and geographic coverage, of a workforce for nutrition. Here, we report the findings of the Castel Gandolfo workshop, a convening of experts from diverse fields in March 2014 to consider how to develop the capacity of a global cadre of nutrition professionals for the post-2015 development era. Workshop participants identified several requirements for developing a workforce for nutrition, including an ability to work as part of a multisectoral team; communication, advocacy, and leadership skills to engage decision makers; and a set of technical skills to address future challenges for nutrition. Other opportunities were highlighted that could immediately contribute to capacity development, including the creation of a consortium to link global North and South universities, online training modules for middle managers, and practical, hands-on experiences for frontline nutrition workers. Institutional and organizational support is needed to enable workshop recommendations on education and training to be effectively implemented and sustained. The findings from the Castel Gandolfo workshop can contribute to the delivery of successful nutrition-relevant actions in the face of mounting external pressures and informing and attaining the forthcoming Sustainable Development Goals. © 2015 American Society for Nutrition.

Enabling Characteristics Of Optical Autocovariance Lidar For Global Wind And Aerosol Profiling

NASA Astrophysics Data System (ADS)

Grund, C. J.; Stephens, M.; Lieber, M.; Weimer, C.

2008-12-01

Systematic global wind measurements with 70 km horizontal resolution and, depending on altitude from the PBL to stratosphere, 250m-2km vertical resolution and 0.5m/s - 2 m/s velocity precision are recognized as key to the understanding and monitoring of complex climate modulations, validation of models, and improved precision and range for weather forecasts. Optical Autocovariance Wind Lidar (OAWL) is a relatively new interferometric direct detection Doppler lidar approach that promises to meet the required wind profile resolution at substantial mass, cost, and power savings, and at reduced technical risk for a space-based system meeting the most demanding velocity precision and spatial and temporal resolution requirements. A proof of concept Optical Autocovariance Wind Lidar (OAWL) has been demonstrated, and a robust multi- wavelength, field-widened (more than 100 microR) lidar system suitable for high altitude (over 16km) aircraft demonstration is under construction. Other advantages of the OAWL technique include insensitivity to aerosol/molecular backscatter mixing ratio, freedom from complex receiver/transmitter optical frequency lock loops, prospects for practical continuous large-area coverage wind profiling from GEO, and the availability of simultaneous multiple wavelength High Spectral Resolution Lidar (OA-HSRL) for aerosol identification and optical property measurements. We will discuss theory, development and demonstration status, advantages, limitations, and space-based performance of OAWL and OA-HSRL, as well as the potential for combined mission synergies.

Beyond new vaccine introduction: the uptake of pneumococcal conjugate vaccine in the African Region.

PubMed

Olayinka, Folake; Ewald, Leah; Steinglass, Robert

2017-01-01

The number of vaccines available to low-income countries has increased dramatically over the last decade. Overall infant immunization coverage in the WHO African region has stagnated in the past few years while countries' ability to maintain high immunization coverage rates following introduction of new vaccines has been uneven. This case study examines post-introduction coverage among African countries that introduced PCV between 2008 and 2013 and the factors affecting Pneumococcal Conjugate Vaccine (PCV) introduction. Nearly one-third of countries did not achieve 80% infant PCV3 coverage by two years post-introduction and 58% of countries experienced a decline in coverage between post introduction years two and four. Major factors affecting coverage rates included introduction without adequate preparation, insufficient supply chain capacity and management, poor communication between organizations and with the public, and data collection systems that were insufficient to meet information needs. Deliberately addressing these issues as well as longstanding weaknesses during new vaccine introduction can strengthen the immunization and broader health system. Further study is required to identify and address factors that affect maintenance of high coverage following introduction of new vaccines in the African region. Immunization with PCV is one of the most important interventions protecting against pneumonia, the second leading cause of death for children under five globally.

CarbonSat Constellation

NASA Astrophysics Data System (ADS)

Sun, Wei; Tobehn, Carsten; Ernst, Robert; Bovensmann, Heinrich; Buchwitz, Michael; Burrows, John P.; Notholt, John

1 Carbon dioxide (CO2) and methane (CH4) are the most important manmade greenhouse gases (GHGs) which are driving global climate change. Currently, the CO2 measurements from the ground observing network are still the main sources of information but due to the limited number of measurement stations the coverage is limited. In addition, CO2 monitoring and trading is often based mainly on bottom-up calculations and an independent top down verification is limited due to the lack of global measurement data with local resolution. The first CO2 and CH4 mapping from SCIAMACHY on ENVISAT shows that satellites add important missing global information. Current GHG measurement satellites (GOSAT)are limited either in spatial or temporal resolution and coverage. These systems have to collect data over a year or even longer to produce global regional fluxes products. Conse-quently global, timely, higher spatial resolution and high accuracy measurement are required for: 1. A good understanding of the CO2 and CH4 sources and sinks for reliable climate predic-tion; and 2. Independent and transparent verification of accountable sources and sinks in supporting Kyoto and upcoming protocols The CarbonSat constellation idea comes out the trade off of resolution and swath width during CarbonSat mission definition studies. In response to the urgent need to support the Kyoto and upcoming protocols, a feasibility study has been carried out. The proposed solution is a constellation of five CarbonSat satellites in 614km LTAN 13:00, which is able to provide global, daily CO2 and CH4 measurement everywhere on the Earth with high spatial resolution 2 × 2 km and low uncertainty lt;2ppm (CO2) and lt;8ppb (CH4). The unique global daily measurement capability significantly increases the number of cloud free measurements, which enables more reliable services associated with reduced uncertainty, e.g. to 0.15ppm (CO2) per month in 10km and even more timely products. The CarbonSat Constellation in combination with inverse modelling techniques will be able to provide information services, such as global quarterly 1. CO2 and CH4 regional flux updates 2. CO2 emission reporting from hot spots e.g. the power plant 3. CH4 emission reporting from hot spots e.g. the pipeline/oil and gas fields. The team led by the industry partner -OHB now promotes an internationally coordinated CarbonSat constellation to provide operational services contributing to the independent iden-tification and verification of man-made & natural CO2 and CH4 emissions and claimed carbon sinks. It is proposed that the CarbonSat Constellation will be implemented through an internation-ally coordinated constellation. Each country contributes one satellite in the constellation and establishes its own ground station to provide data for national applications. A central coordi-nation will be set up for the constellation operation, data calibration and international data distribution. The proposed approach provides independence for each partner and is financially more feasible. In addition, the CarbonSat Constellation consortium could be a bridge/forum between developed countries and developing countries in establishing common understandings of and actions on the global climate change. The world wide transparency provided by this international forum is also critical in supporting Kyoto protocol and upcoming international agreement in man-made Greenhouse emission reduction. The paper will present the CarbonSat Constellation design and the proposed products/ services to verify CO2 and CH4 sources and sinks from a constellation of five CarbonSat satellites through a multilateral collaboration.

Global astrometry with the space interferometry mission

NASA Technical Reports Server (NTRS)

Boden, A.; Unwin, S.; Shao, M.

1997-01-01

The prospects for global astrometric measurements with the space interferometry mission (SIM) are discussed. The SIM mission will perform four microarcsec astrometric measurements on objects as faint as 20 mag using the optical interferometry technique with a 10 m baseline. The SIM satellite will perform narrow angle astrometry and global astrometry by means of an astrometric grid. The sensitivities of the SIM global astrometric performance and the grid accuracy versus instrumental parameters and sky coverage schemes are reported on. The problems in finding suitable astrometric grid objects to support microarcsec astrometry, and related ground-based observation programs are discussed.

Dermal Coverage of Traumatic War Wounds

DTIC Science & Technology

2017-01-01

Device for re-epithelialization of full thickness wounds treated with INTEGRA MBWM. The ReCell Device is a stand-alone, battery operated cell...standalone, battery operated cell separation device that enables preparation of a cell suspension from a small, thin, split-thickness skin biopsy

Estimation of measles vaccination coverage using the Lot Quality Assurance Sampling (LQAS) method--Tamilnadu, India, 2002-2003.

PubMed

Sivasankaran, Saravanan; Manickam, P; Ramakrishnan, R; Hutin, Y; Gupte, M D

2006-04-28

As part of the global strategic plan to reduce the number of measles deaths in India, the state of Tamilnadu aims at > or =95% measles vaccination coverage. A study was conducted to measure overall coverage levels for the Poondi Primary Health Center (PPHC), a rural health-care facility in Tiruvallur District, and to determine whether any of the PPHC's six health subcenters had coverage levels <95%. The Lot Quality Assurance Sampling (LQAS) method was used to identify health subcenters in the PPHC area with measles vaccination coverage levels <95% among children aged 12-23 months. Lemeshow and Taber sampling plans were used to determine that the measles vaccination status of 73 children aged 12--23 months had to be assessed in each health subcenter coverage area, with a 5% level of significance and a decision value of two. If more than two children were unvaccinated, the null hypothesis (i.e., that coverage in the health subcenter was low [<95%]) was not rejected. If the number of unvaccinated children was two or fewer, the null hypothesis was rejected, and coverage in the subcenter was considered to be good (i.e., > or =95%). All data were pooled in a stratified sample to estimate overall total coverage in the PPHC area. For two (33.3%) of the six health subcenters, more than two children were unvaccinated (i.e., coverage was <95%). Combining results from all six health subcenters generated a coverage estimate of 97.7% (95% confidence interval = 95.7-98.8) on the basis of 428 (97.7%) of 438 children identified as vaccinated. LQAS techniques proved useful in identifying small health areas with lower vaccination coverage, which helps to target interventions. Monthly review of vaccination coverage by subcenter and village is recommended to identify pockets of unvaccinated children and to maintain uniform high coverage in the PPHC area.

Impact of oral cholera vaccines in cholera-endemic countries: A mathematical modeling study.

PubMed

Kim, Jong-Hoon; Mogasale, Vittal; Burgess, Colleen; Wierzba, Thomas F

2016-04-19

Impact evaluation of vaccination programs is necessary for making decisions to introduce oral cholera vaccines (OCVs) in cholera-endemic countries. We analyzed data to forecast the future global burden of cholera. We developed a mathematical model of cholera transmission in three countries as examples: Nigeria, Uganda, and Indonesia. After fitting the model, we evaluated the impact of OCVs delivered in four vaccination strategies varying by target age group and frequency of vaccination over the period of 2015-2030. Data suggest that the global annual incidence of cholera will increase from 3046238 in 2015 to 3787385 in 2030 with the highest burden in Asia and Africa where overall population size is large and the proportion of population with access to improved sanitation facilities is low. We estimate that OCV will reduce the cumulative incidence of cholera by half in Indonesia and >80% in Nigeria and Uganda when delivered to 1+ year olds every three years at a coverage rate of 50%, although cholera may persist through higher coverage rates (i.e., >90%). The proportion of person-to-person transmission compared to water-to-person transmission is positively correlated with higher vaccination impact in all three countries. Periodic OCV vaccination every three or five years can significantly reduce the global burden of cholera although cholera may persist even with high OCV coverage. Vaccination impact will likely vary depending on local epidemiological conditions including age distribution of cases and relative contribution of different transmission routes. Copyright © 2016 Elsevier Ltd. All rights reserved.

PREDICT: Privacy and Security Enhancing Dynamic Information Monitoring

DTIC Science & Technology

2015-08-03

consisting of global server-side probabilistic assignment by an untrusted server using cloaked locations, followed by feedback-loop guided local...12], consisting of global server-side probabilistic assignment by an untrusted server using cloaked locations, followed by feedback-loop guided...these methods achieve high sensing coverage with low cost using cloaked locations [3]. In follow-on work, the issue of mobility is addressed. Task

Marine benefits from NASA's global differential system: sub-meter positioning, anywhere, anytime

NASA Technical Reports Server (NTRS)

Bar-Sever, Y.

2000-01-01

Precise real-time, onboard knowledge of a platform s state (position and velocity) is a critical compponent in many marine applications. This article describes a recent technology development that provides a breakthrough in this capability for platforms carrying a dual-frequency GPS receiver - seamless global coverage and roughly an order of magnitude improvement in accuracy compared to state-of-the-art.

Think globally, act locally: the role of local demographics and vaccination coverage in the dynamic response of measles infection to control.

PubMed

Ferrari, M J; Grenfell, B T; Strebel, P M

2013-08-05

The global reduction of the burden of morbidity and mortality owing to measles has been a major triumph of public health. However, the continued persistence of measles infection probably not only reflects local variation in progress towards vaccination target goals, but may also reflect local variation in dynamic processes of transmission, susceptible replenishment through births and stochastic local extinction. Dynamic models predict that vaccination should increase the mean age of infection and increase inter-annual variability in incidence. Through a comparative approach, we assess national-level patterns in the mean age of infection and measles persistence. We find that while the classic predictions do hold in general, the impact of vaccination on the age distribution of cases and stochastic fadeout are mediated by local birth rate. Thus, broad-scale vaccine coverage goals are unlikely to have the same impact on the interruption of measles transmission in all demographic settings. Indeed, these results suggest that the achievement of further measles reduction or elimination goals is likely to require programmatic and vaccine coverage goals that are tailored to local demographic conditions.

Filling a missing link between biogeochemical, climate and ecosystem studies: a global database of atmospheric water-soluble organic nitrogen

NASA Astrophysics Data System (ADS)

Cornell, Sarah

2015-04-01

It is time to collate a global community database of atmospheric water-soluble organic nitrogen deposition. Organic nitrogen (ON) has long been known to be globally ubiquitous in atmospheric aerosol and precipitation, with implications for air and water quality, climate, biogeochemical cycles, ecosystems and human health. The number of studies of atmospheric ON deposition has increased steadily in recent years, but to date there is no accessible global dataset, for either bulk ON or its major components. Improved qualitative and quantitative understanding of the organic nitrogen component is needed to complement the well-established knowledge base pertaining to other components of atmospheric deposition (cf. Vet et al 2014). Without this basic information, we are increasingly constrained in addressing the current dynamics and potential interactions of atmospheric chemistry, climate and ecosystem change. To see the full picture we need global data synthesis, more targeted data gathering, and models that let us explore questions about the natural and anthropogenic dynamics of atmospheric ON. Collectively, our research community already has a substantial amount of atmospheric ON data. Published reports extend back over a century and now have near-global coverage. However, datasets available from the literature are very piecemeal and too often lack crucially important information that would enable aggregation or re-use. I am initiating an open collaborative process to construct a community database, so we can begin to systematically synthesize these datasets (generally from individual studies at a local and temporally limited scale) to increase their scientific usability and statistical power for studies of global change and anthropogenic perturbation. In drawing together our disparate knowledge, we must address various challenges and concerns, not least about the comparability of analysis and sampling methodologies, and the known complexity of composition of ON. We need to discuss and develop protocols that work for diverse research needs. The database will need to be harmonized or merged into existing global N data initiatives. This presentation therefore launches a standing invitation for experts to contribute and share rain and aerosol ON and chemical composition data, and jointly refine the preliminary database structure and metadata requirements for optimal mutual use. Reference: Vet et al. (2014) A global assessment of precipitation chemistry… Atmos Environ 93: 3-100

Global trends in neglected tropical disease control and elimination: impact on child health.

PubMed

Barry, Meagan A; Simon, Gregory G; Mistry, Neeraj; Hotez, Peter J

2013-08-01

The neglected tropical diseases (NTDs) are a group of 17 lesser known chronic infections which predominantly affect poor and disenfranchised communities. There are a number of NTDs that cause significant global morbidity in children, including the three major soil transmitted helminth (STH) infections (ascariasis, trichuriasis and hookworm infection), schistosomiasis and trachoma. These NTDs, together with lymphatic filariasis and onchocerciasis, are currently being targeted for global control and elimination through mass drug administration (MDA) campaigns. They represent the most common NTDs and share significant geographical overlap. Additionally, many individuals are polyparasitised with more than a single NTD. Integrated NTD control and elimination MDA programmes offer safe and efficacious treatments for all seven NTDs. However, the current global level of MDA coverage for the leading childhood NTDs, that is, STH infections, schistosomiasis and trachoma, remains well under 50%. Limiting factors for global coverage include insufficient global financial support, drug donation capacity of pharmaceutical companies and targeting school age children to the exclusion of other age groups in need of treatment, such as preschool age children. There is also a need for development of novel prevention and treatment modalities, such as next-generation small molecule drugs and vaccines. Efforts are underway to harness the momentum of a 2012 London Declaration on NTDs and a 2013 World Health Assembly (WHA) resolution as a means to control or in some cases eliminate by 2020 these NTDs that affect children worldwide.

Treatment of chronic radiation injury over the shoulder with a latissimus dorsi myocutaneous flap

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mendelson, B.C.; Masson, J.K.

1977-11-01

We report our experiences in treating chronic radiation injury about the shoulder, a complication of radiation after mastectomy. Left untreated, these can result in chronic infection and/or amputation. The coverage of a large shoulder area presents certain unique problems, which severely limit the usefulness of traditional procedures. We have found that the remarkable size and versatility of the latissimus dorsi myocutaneous flap enables one to use it with relative simplicity and safety. A further great advantage is that it brings new permanent blood supply into this ischemic area, thus favoring rapid healing and durable coverage.

Multi-angle Imaging SpectroRadiometer

NASA Technical Reports Server (NTRS)

Diner, David J. (Principal Investigator)

MISR views the sunlit Earth simultaneously at nine widely spaced angles and provides ongoing global coverage with high spatial detail. Its imagery is carefully calibrated to provide accurate measures of the brightness, contrast, and color of reflected sunlight. MISR provides new types of information for scientists studying Earth's climate, such as the regional and global distribution of different types of atmospheric particles and aerosols. The change in reflection at different view angles provides the means to distinguish aerosol types, cloud forms, and land surface cover. Combined with stereoscopic techniques, this enables construction of 3-D cloud models and estimation of the total amount of sunlight reflected by Earth's diverse environments. MISR was built for NASA by the Jet Propulsion Laboratory (JPL) in Pasadena, California. It is part of NASA's first Earth Observing System (EOS) spacecraft, the Terra spacecraft, which was launched into polar orbit from Vandenberg Air Force Base on December 18, 1999. MISR has been continuously providing data since February 24, 2000. [Mission Objectives] The MISR instrument acquires systematic multi-angle measurements for global monitoring of top-of-atmosphere and surface albedos and for measuring the shortwave radiative properties of aerosols, clouds, and surface scenes in order to characterize their impact on the Earth's climate. The Earth's climate is constantly changing -- as a consequence of both natural processes and human activities. Scientists care a great deal about even small changes in Earth's climate, since they can affect our comfort and well-being, and possibly our survival. A few years of below-average rainfall, an unusually cold winter, or a change in emissions from a coal-burning power plant, can influence the quality of life of people, plants, and animals in the region involved. The goal of NASA's Earth Observing System (EOS) is to increase our understanding of the climate changes that are occurring on our planet, and the reasons for these changes, so we are better equipped to anticipate and prepare for the future. The MISR instrument is a part of EOS. Its role is to measure the amount of sunlight scattered in different directions under natural conditions. These measurements will help quantify the amount of solar energy that heats the Earth's surface and atmosphere, and the changes that occur in them over the lifetime of the MISR instrument. From the MISR observations, we are also learning more about those components of the Earth's environment that scatter sunlight: particles in the atmosphere, the planet's surface, and clouds. MISR monitors changes in surface reflection properties, in atmospheric aerosol content and composition, and in cloudiness. Scientists use these data to study land use changes, air pollution, volcanic eruptions, as well as processes such as desertification, deforestation, and soil erosion. As part of the EOS program, computer models that predict future climate will be improved by the results of these studies. [Temporal_Coverage: Start_Date=2000-02-24; Stop_Date=] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180].

EarthServer - an FP7 project to enable the web delivery and analysis of 3D/4D models

NASA Astrophysics Data System (ADS)

Laxton, John; Sen, Marcus; Passmore, James

2013-04-01

EarthServer aims at open access and ad-hoc analytics on big Earth Science data, based on the OGC geoservice standards Web Coverage Service (WCS) and Web Coverage Processing Service (WCPS). The WCS model defines "coverages" as a unifying paradigm for multi-dimensional raster data, point clouds, meshes, etc., thereby addressing a wide range of Earth Science data including 3D/4D models. WCPS allows declarative SQL-style queries on coverages. The project is developing a pilot implementing these standards, and will also investigate the use of GeoSciML to describe coverages. Integration of WCPS with XQuery will in turn allow coverages to be queried in combination with their metadata and GeoSciML description. The unified service will support navigation, extraction, aggregation, and ad-hoc analysis on coverage data from SQL. Clients will range from mobile devices to high-end immersive virtual reality, and will enable 3D model visualisation using web browser technology coupled with developing web standards. EarthServer is establishing open-source client and server technology intended to be scalable to Petabyte/Exabyte volumes, based on distributed processing, supercomputing, and cloud virtualization. Implementation will be based on the existing rasdaman server technology developed. Services using rasdaman technology are being installed serving the atmospheric, oceanographic, geological, cryospheric, planetary and general earth observation communities. The geology service (http://earthserver.bgs.ac.uk/) is being provided by BGS and at present includes satellite imagery, superficial thickness data, onshore DTMs and 3D models for the Glasgow area. It is intended to extend the data sets available to include 3D voxel models. Use of the WCPS standard allows queries to be constructed against single or multiple coverages. For example on a single coverage data for a particular area can be selected or data with a particular range of pixel values. Queries on multiple surfaces can be constructed to calculate, for example, the thickness between two surfaces in a 3D model or the depth from ground surface to the top of a particular geologic unit. In the first version of the service a simple interface showing some example queries has been implemented in order to show the potential of the technologies. The project aims to develop the services available in light of user feedback, both in terms of the data available, the functionality and the interface. User feedback on the services guides the software and standards development aspects of the project, leading to enhanced versions of the software which will be implemented in upgraded versions of the services during the lifetime of the project.

Hydrologic Derivatives for Modeling and Analysis—A new global high-resolution database

USGS Publications Warehouse

Verdin, Kristine L.

2017-07-17

The U.S. Geological Survey has developed a new global high-resolution hydrologic derivative database. Loosely modeled on the HYDRO1k database, this new database, entitled Hydrologic Derivatives for Modeling and Analysis, provides comprehensive and consistent global coverage of topographically derived raster layers (digital elevation model data, flow direction, flow accumulation, slope, and compound topographic index) and vector layers (streams and catchment boundaries). The coverage of the data is global, and the underlying digital elevation model is a hybrid of three datasets: HydroSHEDS (Hydrological data and maps based on SHuttle Elevation Derivatives at multiple Scales), GMTED2010 (Global Multi-resolution Terrain Elevation Data 2010), and the SRTM (Shuttle Radar Topography Mission). For most of the globe south of 60°N., the raster resolution of the data is 3 arc-seconds, corresponding to the resolution of the SRTM. For the areas north of 60°N., the resolution is 7.5 arc-seconds (the highest resolution of the GMTED2010 dataset) except for Greenland, where the resolution is 30 arc-seconds. The streams and catchments are attributed with Pfafstetter codes, based on a hierarchical numbering system, that carry important topological information. This database is appropriate for use in continental-scale modeling efforts. The work described in this report was conducted by the U.S. Geological Survey in cooperation with the National Aeronautics and Space Administration Goddard Space Flight Center.

Global temperature definition affects achievement of long-term climate goals

NASA Astrophysics Data System (ADS)

Richardson, Mark; Cowtan, Kevin; Millar, Richard J.

2018-05-01

The Paris Agreement on climate change aims to limit ‘global average temperature’ rise to ‘well below 2 °C’ but reported temperature depends on choices about how to blend air and water temperature data, handle changes in sea ice and account for regions with missing data. Here we use CMIP5 climate model simulations to estimate how these choices affect reported warming and carbon budgets consistent with the Paris Agreement. By the 2090s, under a low-emissions scenario, modelled global near-surface air temperature rise is 15% higher (5%–95% range 6%–21%) than that estimated by an approach similar to the HadCRUT4 observational record. The difference reduces to 8% with global data coverage, or 4% with additional removal of a bias associated with changing sea-ice cover. Comparison of observational datasets with different data sources or infilling techniques supports our model results regarding incomplete coverage. From high-emission simulations, we find that a HadCRUT4 like definition means higher carbon budgets and later exceedance of temperature thresholds, relative to global near-surface air temperature. 2 °C warming is delayed by seven years on average, to 2048 (2035–2060), and CO2 emissions budget for a >50% chance of <2 °C warming increases by 67 GtC (246 GtCO2).

The importance of news media in pharmaceutical risk communication: proceedings of a workshop.

PubMed

Mebane, Felicia E

2005-05-01

In response to mass media's role in the national and global system of pharmaceutical risk communication, the Centers for Education and Research on Therapeutics (CERTs) convened a 'think tank' session on the 'Importance of Media in Pharmaceutical Risk Communication'. Prominent journalists and experts from the pharmaceutical industry, academia, medical practice and government were invited to consider the benefits and challenges of improving the way we communicate the benefits and risks of therapeutics via mass media, especially news media. Workshop discussions revealed a paucity of systematic research directed towards understanding how and why news media report on therapeutic risk, the impact of this coverage and how coverage can be improved. Consequently, participants produced a research agenda capturing the key aspects of the flow of information around this topic, including the meaning of risk, how news audiences process and use therapeutic risk information in the news, how and why news organizations report on therapeutic risk, and the role and impact of the pharmaceutical industry, government officials and academic researchers as sources of therapeutic risk information. The workshop ended with a discussion on action items addressing what news professionals, representatives of regulatory agencies and the medical products industry, and academic researchers can and should do to enable news media to effectively report therapeutic risk information. In sum, this proceedings report provides an outline for developing mass media risk communication research, influencing the practices of journalists and expert sources and ultimately, improving the quality of the public's life. Copyright (c) 2004 John Wiley & Sons, Ltd.

Observing the Anthropocene from Space

NASA Astrophysics Data System (ADS)

Dittus, Hansjörg

2016-07-01

Influence of mankind on Earth's climate is evident. The growing population using the resources available, especially by burning goal, oil and gas, changes the composition of the Earth's atmosphere with the result of a continuously increasing temperature. Effects are not limited to the regional scale but are evident on the whole planet, meanwhile named Anthropocene. According to this global influence, it's necessary to also extend monitoring to the entire planet. Space-based observation systems are not limited by any artificial borders and are in principle able, to cover the whole Earth. In principle, two different ways of observation can be selected: Either a dedicated spacecraft will be send into low earth orbit (LEO) or existing platforms are used. Advantages of satellites are the more or less freely selectable orbit (with orbits covering also the polar regions) and the possible adaption of spacecraft platform for the dedicated instrument. On the other hand platforms like the ISS space station enable continuous long term coverage with different instruments. The drawback of an only limited coverage based on the orbit inclination is made up by the possibility to service systems on the station. Furthermore different generations of sensors can be run in parallel and therefore cross calibrated if needed. This paper reviews the currently available sensors types and discusses potential future needs. Included in this discussion is the international space station as an already available platform for earth observation. Furthermore, discussion should also take into account, that an increasing number of constellations with dozens or even thousand satellites are planned. Are these constellations also an option for an increased temporal and spatial monitoring of the Earth?

Progress toward measles control - African region, 2001-2008.

PubMed

2009-09-25

In 2001, the countries of the World Health Organization (WHO) African Region (AFR) became part of a global initiative with a goal of reducing the number of measles deaths by 50% by 2005, compared with 1999. Recommended strategies for measles mortality reduction included 1) increasing routine coverage for the first dose of measles-containing vaccine (MCV1) for all children, 2) providing a second opportunity for measles vaccination through supplemental immunization activities (SIAs), 3) improving measles case management, and 4) establishing case-based surveillance with laboratory confirmation of all suspected measles cases. Before introduction of MCV throughout AFR, approximately 1 million measles cases had been reported each year in the early 1980s. After strengthening measles-control activities, annual reported cases declined to an estimated 300,000- -580,000 during the 1990s. This report summarizes the progress made during 2001- -2008 toward improving measles control in AFR. During 2001- -2008 estimated MCV1 coverage increased from 57% to 73%, SIAs vaccinated approximately 398 million children, and reported measles cases decreased by 93%, from 492,116 in 2001 to 32,278 in 2008. By 2005, global measles deaths had decreased by 60%, and the AFR goal had been achieved; AFR adopted a new goal to reduce deaths by 90%, compared with 2000, and that goal was achieved in 2006. However, inaccuracies in reported vaccination coverage exist, surveillance is suboptimal, and measles outbreaks continue to occur in AFR countries. Further progress in measles control will require full implementation of recommended strategies, including validation of vaccination coverage.

Undocumented and uninsured: aftereffects of the Patient Protection and Affordable Care Act.

PubMed

Agabin, Nataly; Coffin, Janis

2015-01-01

Although with the implementation of the Patient Protection and Affordable Care Act millions of previously uninsured American residents will gain access to healthcare coverage, millions more will remain uninsured due to the lack of mandatory state Medicaid expansion as well as mandates that forbid undocumented immigrants and legal residents of less than five years from purchasing insurance through the newly available market exchange. With limited options for healthcare coverage due to employment and lack of citizen status, undocumented immigrants rely heavily on funds provided by both Emergency Medicaid and Disproportionate Share Hospital programs. Through reevaluation of current funding, mandates forbidding access to market exchanges, and plans to further enable access to affordable health coverage, states have the unique opportunity to both aid their residents and relieve the financial burden on healthcare facilities and Emergency Medicaid funds.

Spatial Distribution of Trends and Seasonality in the Hemispheric Sea Ice Covers

NASA Technical Reports Server (NTRS)

Gloersen, P.; Parkinson, C. L.; Cavalieri, D. J.; Cosmiso, J. C.; Zwally, H. J.

1998-01-01

We extend earlier analyses of a 9-year sea ice data set that described the local seasonal and trend variations in each of the hemispheric sea ice covers to the recently merged 18.2-year sea ice record from four satellite instruments. The seasonal cycle characteristics remain essentially the same as for the shorter time series, but the local trends are markedly different, in some cases reversing sign. The sign reversal reflects the lack of a consistent long-term trend and could be the result of localized long-term oscillations in the hemispheric sea ice covers. By combining the separate hemispheric sea ice records into a global one, we have shown that there are statistically significant net decreases in the sea ice coverage on a global scale. The change in the global sea ice extent, is -0.01 +/- 0.003 x 10(exp 6) sq km per decade. The decrease in the areal coverage of the sea ice is only slightly smaller, so that the difference in the two, the open water within the packs, has no statistically significant change.

Comparison and quantitative verification of mapping algorithms for whole genome bisulfite sequencing

USDA-ARS?s Scientific Manuscript database

Coupling bisulfite conversion with next-generation sequencing (Bisulfite-seq) enables genome-wide measurement of DNA methylation, but poses unique challenges for mapping. However, despite a proliferation of Bisulfite-seq mapping tools, no systematic comparison of their genomic coverage and quantitat...

Vaccination Coverage Among Children Aged 2 Years - U.S. Affiliated Pacific Islands, April-October, 2016.

PubMed

Tippins, Ashley; Murthy, Neil; Meghani, Mehreen; Solsman, Amy; Apaisam, Carter; Basilius, Merlyn; Eckert, Maribeth; Judicpa, Peter; Masunu, Yolanda; Pistotnik, Kelsey; Pedro, Daisy; Sasamoto, Jeremy; Underwood, J Michael

2018-05-25

Vaccine-preventable diseases (VPDs) cause substantial morbidity and mortality in the United States Affiliated Pacific Islands (USAPI).* CDC collaborates with USAPI immunization programs to monitor vaccination coverage. In 2016, † USAPI immunization programs and CDC piloted a method for estimating up-to-date status among children aged 2 years using medical record abstraction to ascertain regional vaccination coverage. This was the first concurrent assessment of childhood vaccination coverage across five USAPI jurisdictions (American Samoa; Chuuk State, Federated States of Micronesia [FSM]; Commonwealth of the Northern Mariana Islands [CNMI]; Republic of the Marshall Islands [RMI]; and Republic of Palau). § Differences in vaccination coverage between main and outer islands ¶ were assessed for two jurisdictions where data were adequate.** Series coverage in this report includes the following doses of vaccines: ≥4 doses of diphtheria and tetanus toxoids and acellular pertussis vaccine (DTaP); ≥3 doses of inactivated poliovirus vaccine (IPV); ≥1 dose of measles, mumps, and rubella vaccine (MMR); ≥3 doses of Haemophilus influenzae type B (Hib) vaccine; ≥3 doses of hepatitis B (HepB) vaccine; and ≥4 doses of pneumococcal conjugate vaccine (PCV); i.e., 4:3:1:3:3:4. Coverage with ≥3 doses of rotavirus vaccine was also assessed. Completion of the recommended series of each of these vaccines †† was <90% in all jurisdictions except Palau. Coverage with the full recommended six-vaccine series (4:3:1:3:3:4) ranged from 19.5% (Chuuk) to 69.1% (Palau). In RMI and Chuuk, coverage was lower in the outer islands than in the main islands for most vaccines, with differences ranging from 0.9 to 66.8 percentage points. Medical record abstraction enabled rapid vaccination coverage assessment and timely dissemination of results to guide programmatic decision-making. Effectively monitoring vaccination coverage, coupled with implementation of data-driven interventions, is essential to maintain protection from VPD outbreaks in the region and the mainland United States.

Spatial Coverage Planning and Optimization for Planetary Exploration

NASA Technical Reports Server (NTRS)

Gaines, Daniel M.; Estlin, Tara; Chouinard, Caroline

2008-01-01

We are developing onboard planning and scheduling technology to enable in situ robotic explorers, such as rovers and aerobots, to more effectively assist scientists in planetary exploration. In our current work, we are focusing on situations in which the robot is exploring large geographical features such as craters, channels or regional boundaries. In to develop valid and high quality plans, the robot must take into account a range of scientific and engineering constraints and preferences. We have developed a system that incorporates multiobjective optimization and planning allowing the robot to generate high quality mission operations plans that respect resource limitations and mission constraints while attempting to maximize science and engineering objectives. An important scientific objective for the exploration of geological features is selecting observations that spatially cover an area of interest. We have developed a metric to enable an in situ explorer to reason about and track the spatial coverage quality of a plan. We describe this technique and show how it is combined in the overall multiobjective optimization and planning algorithm.

How changes in coverage affect equity in maternal and child health interventions in 35 Countdown to 2015 countries: an analysis of national surveys.

PubMed

Victora, Cesar G; Barros, Aluisio J D; Axelson, Henrik; Bhutta, Zulfiqar A; Chopra, Mickey; França, Giovanny V A; Kerber, Kate; Kirkwood, Betty R; Newby, Holly; Ronsmans, Carine; Boerma, J Ties

2012-09-29

Achievement of global health goals will require assessment of progress not only nationally but also for population subgroups. We aimed to assess how the magnitude of socioeconomic inequalities in health changes in relation to different rates of national progress in coverage of interventions for the health of mothers and children. We assessed coverage in low-income and middle-income countries for which two Demographic Health Surveys or Multiple Indicator Cluster Surveys were available. We calculated changes in overall coverage of skilled birth attendants, measles vaccination, and a composite coverage index, and examined coverage of a newly introduced intervention, use of insecticide-treated bednets by children. We stratified coverage data according to asset-based wealth quintiles, and calculated relative and absolute indices of inequality. We adjusted correlation analyses for time between surveys and baseline coverage levels. We included 35 countries with surveys done an average of 9·1 years apart. Pro-rich inequalities were very prevalent. We noted increased coverage of skilled birth attendants, measles vaccination, and the composite index in most countries from the first to the second survey, while inequalities were reduced. Rapid changes in overall coverage were associated with improved equity. These findings were not due to a capping effect associated with limited scope for improvement in rich households. For use of insecticide-treated bednets, coverage was high for the richest households, but countries making rapid progress did almost as well in reaching the poorest groups. National increases in coverage were primarily driven by how rapidly coverage increased in the poorest quintiles. Equity should be accounted for when planning the scaling up of interventions and assessing national progress. Bill & Melinda Gates Foundation; World Bank; Governments of Australia, Brazil, Canada, Norway, Sweden, and UK. Copyright © 2012 Elsevier Ltd. All rights reserved.

Collective network for computer structures

DOEpatents

Blumrich, Matthias A; Coteus, Paul W; Chen, Dong; Gara, Alan; Giampapa, Mark E; Heidelberger, Philip; Hoenicke, Dirk; Takken, Todd E; Steinmacher-Burow, Burkhard D; Vranas, Pavlos M

2014-01-07

A system and method for enabling high-speed, low-latency global collective communications among interconnected processing nodes. The global collective network optimally enables collective reduction operations to be performed during parallel algorithm operations executing in a computer structure having a plurality of the interconnected processing nodes. Router devices are included that interconnect the nodes of the network via links to facilitate performance of low-latency global processing operations at nodes of the virtual network. The global collective network may be configured to provide global barrier and interrupt functionality in asynchronous or synchronized manner. When implemented in a massively-parallel supercomputing structure, the global collective network is physically and logically partitionable according to the needs of a processing algorithm.

Collective network for computer structures

DOEpatents

Blumrich, Matthias A [Ridgefield, CT; Coteus, Paul W [Yorktown Heights, NY; Chen, Dong [Croton On Hudson, NY; Gara, Alan [Mount Kisco, NY; Giampapa, Mark E [Irvington, NY; Heidelberger, Philip [Cortlandt Manor, NY; Hoenicke, Dirk [Ossining, NY; Takken, Todd E [Brewster, NY; Steinmacher-Burow, Burkhard D [Wernau, DE; Vranas, Pavlos M [Bedford Hills, NY

2011-08-16

A system and method for enabling high-speed, low-latency global collective communications among interconnected processing nodes. The global collective network optimally enables collective reduction operations to be performed during parallel algorithm operations executing in a computer structure having a plurality of the interconnected processing nodes. Router devices ate included that interconnect the nodes of the network via links to facilitate performance of low-latency global processing operations at nodes of the virtual network and class structures. The global collective network may be configured to provide global barrier and interrupt functionality in asynchronous or synchronized manner. When implemented in a massively-parallel supercomputing structure, the global collective network is physically and logically partitionable according to needs of a processing algorithm.

Maternal Health Service Disparities Across Incomes and Implications on Prevention of Mother-to-Child Transmission Service Coverage: Current Context in Sub-Saharan Africa.

PubMed

Workneh, Nibretie Gobezie; Kevany, Sebastian

2016-12-31

About 69% of people living with HIV globally and over 90% of the children who acquired HIV infection are in Sub-Saharan Africa. Despite this, promising results have been observed, especially over the last decade - for example, a 25% decline in new HIV infections as compared to 2001 and a 38% decline in the number of children newly infected by HIV in 2012 as compared to 2009. However, the Global Plan and the Global Fast-Track Commitments of eliminating new HIV infections among children require addressing impediments to service expansion. In this regard, this paper attempts to draw attention to the extent to which disparities across income in using antenatal care (ANC) services may constrain the prevention of mother-to-child transmission (PMTCT) service expansion in Sub-Saharan Africa. The analysis is based on ANC service coverage data from Demographic and Health Surveys conducted between 2008 and 2015 in 31 Sub-Saharan African countries; and PMTCT coverage data from UNAIDS datasets released in 2016. Our analysis found that women in the highest wealth quintile are about three times more likely to frequently use ANC services (at least four visits) as compared to those in the lowest wealth quintile (95%CI: 1.7-5.7, P<0.0001). A regression analysis shows that one-quarter of the PMTCT service coverage can be explained by the disparity in ANC use associated with income; and the higher the disparity in ANC use, the lower the PMTCT service (P<0.05). The findings suggest that achieving the ambitious plan of zero new HIV infections among children while keeping their mothers alive will require on-going PMTCT/ANC service integration and ensuring that programs reach women who are most in need; specifically those in the poorest income categories.

Global Rotavirus Vaccine Introductions and Coverage: 2006 - 2016.

PubMed

Abou-Nader, Alice; Sauer, Molly; Steele, A Duncan; Tate, Jacqueline E; Atherly, Deborah; Parashar, Umesh D; Santosham, Mathuram; Nelson, E Anthony S

2018-05-22

An estimated 215,000 children died of rotavirus infections in 2013, accounting for 37% of diarrhea-related deaths worldwide, 92% of which occurred in low and lower-middle income countries. Since 2009 the World Health Organization (WHO) recommends the use of rotavirus vaccines in all national immunization programs. This review compares rotavirus vaccine (RV) introductions and vaccine coverage by region, country income status and Gavi-eligibility from 2006-2016. Gross National Income data from the World Bank and surviving infant population from United Nations Population Division was obtained for 2016. Data from WHO were collected on rotavirus vaccine coverage, national immunization schedules, and new vaccine introductions for 2016 while estimated rotavirus deaths were collected for 2013, the last year of available WHO data. As of December 2016, the majority of countries (57%, 110/194) had not introduced universal rotavirus vaccine despite WHO's 2009 recommendation to do so. Countries in the WHO African region had the greatest proportion of introductions (37%, 31/84) by December 2016 and a great majority of these (77%, 24/31) were supported by new vaccine introduction (NVI) grants from Gavi. Almost half (48%) of global introductions were in low and lower-middle income Gavi-eligible and Gavi-graduating countries. Conversely, countries in the Southeast Asia WHO region and those not eligible for Gavi NVI support have been slow to introduce rotavirus vaccine. High-income countries, on average, had poorer rotavirus vaccine coverage compared to low and lower-middle income countries. The over-representation of African countries within the Gavi subset and high estimated rotavirus deaths in these African countries, likely explains why introduction efforts have been focused in this region. While much progress has been made with the integration and implementation of rotavirus vaccine into national immunization programs, 110 countries representing 69% of the global birth cohort had yet to introduce the vaccine by December 2016.

Large Scale Variability of Mid-Tropospheric Carbon Dioxide as Observed by the Atmospheric Infrared Sounder (AIRS) on the NASA EOS Aqua Platform

NASA Technical Reports Server (NTRS)

Pagano, Thomas S.; Olsen, Edward T.

2012-01-01

The Atmospheric Infrared Sounder (AIRS) is a hyperspectral infrared instrument on the EOS Aqua Spacecraft, launched on May 4, 2002. AIRS has 2378 infrared channels ranging from 3.7 microns to 15.4 microns and a 13.5 km footprint. AIRS, in conjunction with the Advanced Microwave Sounding Unit (AMSU), produces temperature profiles with 1K/km accuracy, water vapor profiles (20%/2km), infrared cloud height and fraction, and trace gas amounts for CO2, CO, SO2, O3 and CH4 in the mid to upper troposphere. AIRS wide swath(cedilla) +/-49.5 deg , enables daily global daily coverage for over 95% of the Earth's surface. AIRS data are used for weather forecasting, validating climate model distribution and processes, and observing long-range transport of greenhouse gases. In this study, we examine the large scale and regional horizontal variability in the AIRS Mid-tropospheric Carbon Dioxide product as a function of season and associate the observed variability with known atmospheric transport processes, and sources and sinks of CO2.

Mars Communication Protocols

NASA Technical Reports Server (NTRS)

Kazz, G. J.; Greenberg, E.

2000-01-01

Over the next decade, international plans and commitments are underway to develop an infrastructure at Mars to support future exploration of the red planet. The purpose of this infrastructure is to provide reliable global communication and navigation coverage for on-approach, landed, roving, and in-flight assets at Mars. The claim is that this infrastructure will: 1) eliminate the need of these assets to carry Direct to Earth (DTE) communications equipment, 2) significantly increase data return and connectivity, 3) enable small mission exploration of Mars without DTE equipment, 4) provide precision navigation i.e., 10 to 100m position resolution, 5) supply timing reference accurate to 10ms. This paper in particular focuses on two CCSDS recommendations for that infrastructure: CCSDS Proximity-1 Space Link Protocol and CCSDS File Delivery Protocol (CFDP). A key aspect of Mars exploration will be the ability of future missions to interoperate. These protocols establish a framework for interoperability by providing standard communication, navigation, and timing services. In addition, these services include strategies to recover gracefully from communication interruptions and interference while ensuring backward compatibility with previous missions from previous phases of exploration.

Power attenuation characteristics as switch-over criterion in personal satellite mobile communications

NASA Technical Reports Server (NTRS)

Castro, Jonathan P.

1993-01-01

A third generation mobile system intends to support communications in all environments (i.e., outdoors, indoors at home or office and when moving). This system will integrate services that are now available in architectures such as cellular, cordless, mobile data networks, paging, including satellite services to rural areas. One way through which service integration will be made possible is by supporting a hierarchical cellular structure based on umbrella cells, macro cells, micro and pico cells. In this type of structure, satellites are part of the giant umbrella cells allowing continuous global coverage, the other cells belong to cities, neighborhoods, and buildings respectively. This does not necessarily imply that network operation of terrestrial and satellite segments interconnect to enable roaming and spectrum sharing. However, the cell concept does imply hand-off between different cell types, which may involve change of frequency. Within this propsective, the present work uses power attenuation characteristics to determine a dynamic criterion that allows smooth transition from space to terrestrial networks. The analysis includes a hybrid channel that combines Rician, Raleigh and Log Normal fading characteristics.

The ALMA Phasing System: A Beamforming Capability for Ultra-high-resolution Science at (Sub)Millimeter Wavelengths

NASA Astrophysics Data System (ADS)

Matthews, L. D.; Crew, G. B.; Doeleman, S. S.; Lacasse, R.; Saez, A. F.; Alef, W.; Akiyama, K.; Amestica, R.; Anderson, J. M.; Barkats, D. A.; Baudry, A.; Broguière, D.; Escoffier, R.; Fish, V. L.; Greenberg, J.; Hecht, M. H.; Hiriart, R.; Hirota, A.; Honma, M.; Ho, P. T. P.; Impellizzeri, C. M. V.; Inoue, M.; Kohno, Y.; Lopez, B.; Martí-Vidal, I.; Messias, H.; Meyer-Zhao, Z.; Mora-Klein, M.; Nagar, N. M.; Nishioka, H.; Oyama, T.; Pankratius, V.; Perez, J.; Phillips, N.; Pradel, N.; Rottmann, H.; Roy, A. L.; Ruszczyk, C. A.; Shillue, B.; Suzuki, S.; Treacy, R.

2018-01-01

The Atacama Millimeter/submillimeter Array (ALMA) Phasing Project (APP) has developed and deployed the hardware and software necessary to coherently sum the signals of individual ALMA antennas and record the aggregate sum in Very Long Baseline Interferometry (VLBI) Data Exchange Format. These beamforming capabilities allow the ALMA array to collectively function as the equivalent of a single large aperture and participate in global VLBI arrays. The inclusion of phased ALMA in current VLBI networks operating at (sub)millimeter wavelengths provides an order of magnitude improvement in sensitivity, as well as enhancements in u–v coverage and north–south angular resolution. The availability of a phased ALMA enables a wide range of new ultra-high angular resolution science applications, including the resolution of supermassive black holes on event horizon scales and studies of the launch and collimation of astrophysical jets. It also provides a high-sensitivity aperture that may be used for investigations such as pulsar searches at high frequencies. This paper provides an overview of the ALMA Phasing System design, implementation, and performance characteristics.

Study of Global Health Strategy Based on International Trends: -Promoting Universal Health Coverage Globally and Ensuring the Sustainability of Japan's Universal Coverage of Health Insurance System: Problems and Proposals.

PubMed

Hatanaka, Takashi; Eguchi, Narumi; Deguchi, Mayumi; Yazawa, Manami; Ishii, Masami

2015-09-01

The Japanese government at present is implementing international health and medical growth strategies mainly from the viewpoint of business. However, the United Nations is set to resolve the Post-2015 Development Agenda in the fall of 2015; the agenda will likely include the achievement of universal health coverage (UHC) as a specific development goal. Japan's healthcare system, the foundation of which is its public, nationwide universal health insurance program, has been evaluated highly by the Lancet. The World Bank also praised it as a global model. This paper presents suggestions and problems for Japan regarding global health strategies, including in regard to several prerequisite domestic preparations that must be made. They are summarized as follows. (1) The UHC development should be promoted in coordination with the United Nations, World Bank, and Asian Development Bank. (2) The universal health insurance system of Japan can be a global model for UHC and ensuring its sustainability should be considered a national policy. (3) Trade agreements such as the Trans-Pacific Partnership (TPP) should not disrupt or interfere with UHC, the form of which is unique to each nation, including Japan. (4) Japan should disseminate information overseas, including to national governments, people, and physicians, regarding the course of events that led to the establishment of the Japan's universal health insurance system and should make efforts to develop international human resources to participate in UHC policymaking. (5) The development of separate healthcare programs and UHC preparation should be promoted by streamlining and centralizing maternity care, school health, infectious disease management such as for tuberculosis, and emergency medicine such as for traffic accidents. (6) Japan should disseminate information overseas about its primary care physicians (kakaritsuke physicians) and develop international human resources. (7) Global health should be developed in integration with global environment problem management. (8) Support systems, such as for managing large-scale disasters of international scale or preventing the spread of infectious diseases, should be developed and maintained. (9) International healthcare policy, which the Japanese government is trying to promote in accordance with international trends, and international development of Japanese healthcare industry should be reconsidered.

Signals of Opportunity Earth Reflectometry (SoOp-ER): Enabling new microwave observations from small satellites

NASA Astrophysics Data System (ADS)

Garrison, J. L.; Piepmeier, J. R.; Shah, R.; Lin, Y. C.; Du Toit, C. F.; Vega, M. A.; Knuble, J. J.

2016-12-01

Several recent experiments have demonstrated remote sensing by reutilizing communication satellite transmissions as sources in a bistatic radar configuration. This technique, referred to as "Signals of Opportunity Earth Reflectometry" (SoOp-ER), combines aspects of passive radiometry, active scatterometry and radar altimetry, but is essentially a new and alternative approach to microwave remote sensing. Reflectometry was first demonstrated with Global Navigation Satellite System (GNSS) signals, enabled by their use of pseudorandom noise (PRN) codes for ranging. Two decades of research in GNSS reflectometry has culminated in the upcoming launches of several satellite missions within the next few years (TechDemoSat-1, CYGNSS, and GEROS-ISS). GNSS signals, however, have low power and are confined to a few L-band frequencies allocated to radionavigation. Communication satellites, in contrast, transmit in nearly all bands penetrating the Earth's atmosphere at very high radiated powers to assure a low bit-error-rate. High transmission power and a forward scatter geometry result in a very high signal to noise ratio at the receiver. Surface resolution is determined by the signal bandwidth, not the antenna beam. In many applications, this will allow small, low gain antennas to be used to make scientifically useful measurements. These features indicate that SoOp-ER instruments would be an ideal technology for microwave remote sensing from small platforms. SoOp-ER observations are referenced at the specular point and a constellation of small satellites, evenly spaced in the same orbit, would provide global coverage through parallel specular point ground tracks. This presentation will summarize the current instrument development work by the authors on three different application of SoOp-ER: P-band (230-270 MHz) sensing of root-zone soil moisture (RZSM), S-band sensing of ocean winds and Ku/Ka-band altimetry. Potential mission scenarios using small satellite constellations using SoOp-ER at these frequencies are under study.

Study on generation and sharing of on-demand global seamless data—Taking MODIS NDVI as an example

NASA Astrophysics Data System (ADS)

Shen, Dayong; Deng, Meixia; Di, Liping; Han, Weiguo; Peng, Chunming; Yagci, Ali Levent; Yu, Genong; Chen, Zeqiang

2013-04-01

By applying advanced Geospatial Data Abstraction Library (GDAL) and BigTIFF technology in a Geographical Information System (GIS) with Service Oriented Architecture (SOA), this study has derived global datasets using tile-based input data and implemented Virtual Web Map Service (VWMS) and Virtual Web Coverage Service (VWCS) to provide software tools for visualization and acquisition of global data. Taking MODIS Normalized Difference Vegetation Index (NDVI) as an example, this study proves the feasibility, efficiency and features of the proposed approach.

Global Precipitation Measurement (GPM) Mission Development Status

NASA Technical Reports Server (NTRS)

Azarbarzin, Ardeshir Art

2011-01-01

Mission Objective: (1) Improve scientific understanding of the global water cycle and fresh water availability (2) Improve the accuracy of precipitation forecasts (3) Provide frequent and complete sampling of the Earth s precipitation Mission Description (Class B, Category I): (1) Constellation of spacecraft provide global precipitation measurement coverage (2) NASA/JAXA Core spacecraft: Provides a microwave radiometer (GMI) and dual-frequency precipitation radar (DPR) to cross-calibrate entire constellation (3) 65 deg inclination, 400 km altitude (4) Launch July 2013 on HII-A (5) 3 year mission (5 year propellant) (6) Partner constellation spacecraft.

Explaining socio-economic inequalities in immunization coverage in Nigeria.

PubMed

Ataguba, John E; Ojo, Kenneth O; Ichoku, Hyacinth E

2016-11-01

Globally, in 2013 over 6 million children younger than 5 years died from either an infectious cause or during the neonatal period. A large proportion of these deaths occurred in developing countries, especially in sub-Saharan Africa. Immunization is one way to reduce childhood morbidity and deaths. In Nigeria, however, although immunization is provided without a charge at public facilities, coverage remains low and deaths from vaccine preventable diseases are high. This article seeks to assess inequalities in full and partial immunization coverage in Nigeria. It also assesses inequality in the 'intensity' of immunization coverage and it explains the factors that account for disparities in child immunization coverage in the country. Using nationally representative data, this article shows that disparities exist in the coverage of immunization to the advantage of the rich. Also, factors such as mother's literacy, region and location of the child, and socio-economic status explain the disparities in immunization coverage in Nigeria. Apart from addressing these issues, the article notes the importance of addressing other social determinants of health to reduce the disparities in immunization coverage in the country. These should be in line with the social values of communities so as to ensure acceptability and compliance. We argue that any policy that addresses these issues will likely reduce disparities in immunization coverage and put Nigeria on the road to sustainable development. © The Author 2016. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

The Role of Discrete Global Grid Systems in the Global Statistical Geospatial Framework

NASA Astrophysics Data System (ADS)

Purss, M. B. J.; Peterson, P.; Minchin, S. A.; Bermudez, L. E.

2016-12-01

The United Nations Committee of Experts on Global Geospatial Information Management (UN-GGIM) has proposed the development of a Global Statistical Geospatial Framework (GSGF) as a mechanism for the establishment of common analytical systems that enable the integration of statistical and geospatial information. Conventional coordinate reference systems address the globe with a continuous field of points suitable for repeatable navigation and analytical geometry. While this continuous field is represented on a computer in a digitized and discrete fashion by tuples of fixed-precision floating point values, it is a non-trivial exercise to relate point observations spatially referenced in this way to areal coverages on the surface of the Earth. The GSGF states the need to move to gridded data delivery and the importance of using common geographies and geocoding. The challenges associated with meeting these goals are not new and there has been a significant effort within the geospatial community to develop nested gridding standards to tackle these issues over many years. These efforts have recently culminated in the development of a Discrete Global Grid Systems (DGGS) standard which has been developed under the auspices of Open Geospatial Consortium (OGC). DGGS provide a fixed areal based geospatial reference frame for the persistent location of measured Earth observations, feature interpretations, and modelled predictions. DGGS address the entire planet by partitioning it into a discrete hierarchical tessellation of progressively finer resolution cells, which are referenced by a unique index that facilitates rapid computation, query and analysis. The geometry and location of the cell is the principle aspect of a DGGS. Data integration, decomposition, and aggregation is optimised in the DGGS hierarchical structure and can be exploited for efficient multi-source data processing, storage, discovery, transmission, visualization, computation, analysis, and modelling. During the 6th Session of the UN-GGIM in August 2016 the role of DGGS in the context of the GSGF was formally acknowledged. This paper proposes to highlight the synergies and role of DGGS in the Global Statistical Geospatial Framework and to show examples of the use of DGGS to combine geospatial statistics with traditional geoscientific data.

LEOPACK The integrated services communications system based on LEO satellites

NASA Astrophysics Data System (ADS)

Negoda, A.; Bunin, S.; Bushuev, E.; Dranovsky, V.

LEOPACK is yet another LEO satellite project which provides global integrated services for 'business' communications. It utilizes packet rather then circuit switching in both terrestrial and satellite chains as well as cellular approach for frequencies use. Original multiple access protocols and decentralized network control make it possible to organize regionally or logically independent and world-wide networks. Relatively small number of satellites (28) provides virtually global network coverage.

Global costs and benefits of reaching universal coverage of sanitation and drinking-water supply.

PubMed

Hutton, Guy

2013-03-01

Economic evidence on the cost and benefits of sanitation and drinking-water supply supports higher allocation of resources and selection of efficient and affordable interventions. The study aim is to estimate global and regional costs and benefits of sanitation and drinking-water supply interventions to meet the Millennium Development Goal (MDG) target in 2015, as well as to attain universal coverage. Input data on costs and benefits from reviewed literature were combined in an economic model to estimate the costs and benefits, and benefit-cost ratios (BCRs). Benefits included health and access time savings. Global BCRs (Dollar return per Dollar invested) were 5.5 for sanitation, 2.0 for water supply and 4.3 for combined sanitation and water supply. Globally, the costs of universal access amount to US$ 35 billion per year for sanitation and US$ 17.5 billion for drinking-water, over the 5-year period 2010-2015 (billion defined as 10(9) here and throughout). The regions accounting for the major share of costs and benefits are South Asia, East Asia and sub-Saharan Africa. Improved sanitation and drinking-water supply deliver significant economic returns to society, especially sanitation. Economic evidence should further feed into advocacy efforts to raise funding from governments, households and the private sector.

Sensor-driven area coverage for an autonomous fixed-wing unmanned aerial vehicle.

PubMed

Paull, Liam; Thibault, Carl; Nagaty, Amr; Seto, Mae; Li, Howard

2014-09-01

Area coverage with an onboard sensor is an important task for an unmanned aerial vehicle (UAV) with many applications. Autonomous fixed-wing UAVs are more appropriate for larger scale area surveying since they can cover ground more quickly. However, their non-holonomic dynamics and susceptibility to disturbances make sensor coverage a challenging task. Most previous approaches to area coverage planning are offline and assume that the UAV can follow the planned trajectory exactly. In this paper, this restriction is removed as the aircraft maintains a coverage map based on its actual pose trajectory and makes control decisions based on that map. The aircraft is able to plan paths in situ based on sensor data and an accurate model of the on-board camera used for coverage. An information theoretic approach is used that selects desired headings that maximize the expected information gain over the coverage map. In addition, the branch entropy concept previously developed for autonomous underwater vehicles is extended to UAVs and ensures that the vehicle is able to achieve its global coverage mission. The coverage map over the workspace uses the projective camera model and compares the expected area of the target on the ground and the actual area covered on the ground by each pixel in the image. The camera is mounted on a two-axis gimbal and can either be stabilized or optimized for maximal coverage. Hardware-in-the-loop simulation results and real hardware implementation on a fixed-wing UAV show the effectiveness of the approach. By including the already developed automatic takeoff and landing capabilities, we now have a fully automated and robust platform for performing aerial imagery surveys.

SeaWinds Global Coverage with Detail of Hurricane Floyd

NASA Image and Video Library

2000-05-07

The distribution of ocean surface winds over the Atlantic Ocean, based on September 1999 data from NASA SeaWinds instrument on the QuikScat satellite, shows wind direction, superimposed on the color image indicating wind speed.

Color Map of Ceres Elliptical Projection

NASA Image and Video Library

2016-03-22

This global map elliptical map from NASA Dawn spacecraft shows the surface of Ceres in enhanced color, encompassing infrared wavelengths beyond human visual range. Some areas near the poles are black where Dawn color imaging coverage is incomplete.

The Updating of Geospatial Base Data

NASA Astrophysics Data System (ADS)

Alrajhi, Muhamad N.; Konecny, Gottfried

2018-04-01

Topopographic mapping issues concern the area coverage at different scales and their age. The age of the map is determined by the system of updating. The United Nations (UNGGIM) have attempted to track the global map coverage at various scale ranges, which has greatly improved in recent decades. However the poor state of updating of base maps is still a global problem. In Saudi Arabia large scale mapping is carried out for all urban, suburban and rural areas by aerial surveys. Updating is carried out by remapping every 5 to 10 years. Due to the rapid urban development this is not satisfactory, but faster update methods are forseen by use of high resolution satellite imagery and the improvement of object oriented geodatabase structures, which will permit to utilize various survey technologies to update the photogrammetry established geodatabases. The longterm goal is to create an geodata infrastructure, which exists in Great Britain or Germany.

Global ice and land climate studies using scatterometer image data

NASA Astrophysics Data System (ADS)

Long, David G.; Drinkwater, Mark R.; Holt, Benjamin; Saatchi, Sasan; Bertoia, Cheryl

Scatterometers have provided continuous synoptic microwave radar coverage of the Earth from space for nearly a decade. NASA launched three scatterometers: the current SeaWinds scatterometer onboard QuikSCAT (QSCAT, 13.4 GHz) launched in 1999; the NASA scatterometer (NSCAT, 14.0 GHz), which flew on the Japanese Space Agency's ADEOS-1 platform during 1996-1997 and the Seasat-A scatterometer system (SASS, 14.6 GHz), which flew in 1978. The European Space Agency's (ESA) 5.3-GHz scatterometer (ESCAT) has been carried onboard both the ERS-1 and ERS-2 satellites since 1991.properties, including the phase state, of a particular surface type. Varying response from the surface also results from different polarizations, viewing angles and orientations, and radar frequencies. The wide swath of scatterometers provides near daily global coverage at intrinsic sensor resolutions that are generally between 25-50 km.

A GPS coverage model

NASA Technical Reports Server (NTRS)

Skidmore, Trent A.

1994-01-01

The results of several case studies using the Global Positioning System coverage model developed at Ohio University are summarized. Presented are results pertaining to outage area, outage dynamics, and availability. Input parameters to the model include the satellite orbit data, service area of interest, geometry requirements, and horizon and antenna mask angles. It is shown for precision-landing Category 1 requirements that the planned GPS 21 Primary Satellite Constellation produces significant outage area and unavailability. It is also shown that a decrease in the user equivalent range error dramatically decreases outage area and improves the service availability.

Development of JPSS VIIRS Global Gridded Vegetation Index products for NOAA NCEP Environmental Modeling Systems

NASA Astrophysics Data System (ADS)

Vargas, Marco; Miura, Tomoaki; Csiszar, Ivan; Zheng, Weizhong; Wu, Yihua; Ek, Michael

2017-04-01

The first Joint Polar Satellite System (JPSS) mission, the Suomi National Polar-orbiting Partnership (S-NPP) satellite, was successfully launched in October, 2011, and it will be followed by JPSS-1, slated for launch in 2017. JPSS provides operational continuity of satellite-based observations and products for NOAA's Polar Operational Environmental Satellites (POES). Vegetation products derived from satellite measurements are used for weather forecasting, land modeling, climate research, and monitoring the environment including drought, the health of ecosystems, crop monitoring and forest fires. The operationally produced S-NPP VIIRS Vegetation Index (VI) Environmental Data Record (EDR) includes two vegetation indices: the Top of the Atmosphere (TOA) Normalized Difference Vegetation Index (NDVI), and the Top of the Canopy (TOC) Enhanced Vegetation Index (EVI). For JPSS-1, the S-NPP Vegetation Index EDR algorithm has been updated to include the TOC NDV. The current JPSS operational VI products are generated in granule style at 375 meter resolution at nadir, but these products in granule format cannot be ingested into NOAA operational monitoring and decision making systems. For that reason, the NOAA JPSS Land Team is developing a new global gridded Vegetation Index (VI) product suite for operational use by the NOAA National Centers for Environmental Prediction (NCEP). The new global gridded VIs will be used in the Multi-Physics (MP) version of the Noah land surface model (Noah-MP) in NCEP NOAA Environmental Modeling System (NEMS) for plant growth and data assimilation and to describe vegetation coverage and density in order to model the correct surface energy partition. The new VI 4km resolution global gridded products (TOA NDVI, TOC NDVI and TOC EVI) are being designed to meet the needs of directly ingesting vegetation index variables without the need to develop local gridding and compositing procedures. These VI products will be consistent with the already operational SNPP VIIRS Green Vegetation Fraction (GVF) global gridded 4km resolution. The ultimate goal is a global consistent set of global gridded land products at 1-km resolution to enable consistent use of the products in the full suite of global and regional NCEP land models. The new JPSS vegetation products system is scheduled to transition to operations in the fall of 2017.

Eavesdropping on the Arctic: Automated Bioacoustics Promise to Untangle Climate-Induced Shifts in Songbird Migration

NASA Astrophysics Data System (ADS)

Oliver, R.; Ellis, D.; Gough, L.; Chmura, H.; Sweet, S. K.; Boelman, N.; Krause, J.; Perez, J.; Wingfield, J.

2017-12-01

Climate change is altering the seasonality of environmental conditions and the phenology of vegetation, particularly at high northern latitudes. Yet changes in the phenology of wildlife that rely on northern ecosystems is significantly understudied. In much the same way that remote sensing enables global-scale observations of climate and vegetation, ground-based bioacoustic recording networks have the potential to vastly expand the spatial and temporal coverage of wildlife monitoring. However, the enormous datasets that autonomous recorders typically generate demand automated analyses that remain largely undeveloped. To unleash the potential for global-scale bioacoustic monitoring, we developed automated signal processing and machine learning algorithms to generate seasonal times series of breeding songbird vocal activity from 1200 hours of landscape-level recordings in northern Alaska. The calendar dates on which songbird communities arrived to their breeding grounds in five springs (2010-2014) were automatically extracted from the time series, and agreed within 3 days to those determined via traditional avian surveys (RMSE = 1.88 - 3.02). Relative to other years, our bioacoustic approach identified a 1-9 day delay in the arrival of long distance migratory songbird communities to their breeding grounds in 2013 - a spring characterized by persistent snow cover and cold temperatures. Differences in arrival timing among sites were strongly related to the date on which the landscape surrounding the microphone became snow-free, particularly in the supervised approach (supervised: R2 = 0.59, p < 0.01 and unsupervised: R2 = 0.13, p = 0.15). We found daily variation in vocal activity was heavily influenced by environmental conditions - primarily snow cover and temperature, and especially prior to egg laying (R2 = 0.61 +/- 0.07 vs. 0.23 +/- 0.07, p < 0.1) - suggesting that extending bioacoustics analysis beyond arrival date estimation requires coupling recordings with meteorological networks and information on community breeding phenology. The success of our novel analytical approach demonstrates that shifts in avian migratory behavior could be detected autonomously, which would provide the coverage necessary to determine and project the influence of climate on rapidly changing ecosystems.

eodataservice.org: how to enable cross-continental interoperability of the European Space Agency and Australian Geoscience Landsat datacubes

NASA Astrophysics Data System (ADS)

Mantovani, Simone; Barboni, Damiano; Natali, Stefano; Evans, Ben; Steer, Adam; Hogan, Patrik; Baumann, Peter

2017-04-01

Globally, billions of dollars are invested annually in Earth observations that support public services, commercial activity, and scientific inquiry. The Common Data Framework [1] for Earth Observation data summarises the current standards for the international community to adopt a common approach so that this significant data can be readily accessible. Concurrently, the "Copernicus Cooperation Arrangement" between the European Commission and the Australian Government is just one in a number of recent agreements signed to facilitate Satellite Earth Observation data sharing among the users' communities. The typical approach implemented in these initiatives is the establishment of a regional data access hub managed by the regional entity to collect data at full scale or over the local region, improve access services and provide high-performance environment in which all the data can be analysed. Furthermore, a number of datacube-aware platforms and services have emerged that enable a new collaborative approach for analysing the vast quantities of satellite imagery and other Earth Observations, making it quicker and easier to explore a time series of image data. In this context, the H2020-funded EarthServer2 project brings together multiple organisations in Europe, Australia and United States to allow federated data holdings to be analysed using web-based access to petabytes of multidimensional geospatial datasets. The aim is to create and ensure that these large spatial data sources can be accessed based on OGC standards, namely Web Coverage Service (WCS) and Web Coverage Processing Service (WCPS) that provide efficient&timely retrieval of large volumes of geospatial data as well as on-the-fly processing. In this study, we provide an overview of the existing European Space Agency and Australian Geoscience Landsat datacubes, how the regional datacube structures differ, how interoperability is enabled through standards, and finally how the datacubes can be visualized on a virtual globe (NASA - ESA WebWorldWind) based on a WC(P)S query via any standard internet browser. The current study is co-financed by the European Space Agency under the MaaS project (ESRIN Contract No. 4000114186/15/I-LG) and the European Union's Horizon 2020 research and innovation programme under the EarthServer-2 project (Grant Agreement No. 654367) [1] Common framework for Earth-Observation data, March 23, 2016 (https://www.whitehouse.gov/sites/default/files/microsites/ostp/common_framework_for_earth_observation_data.pdf)

Vaccines, inspiring innovation in health.

PubMed

Pagliusi, Sonia; Dennehy, Maureen; Kim, Hun

2018-05-19

This report covers the topics of pandemics, epidemics and partnerships, including regulatory convergence initiatives, new technologies and novel vaccines, discussed by leading public and private sector stakeholders at the 18th Annual General Meeting (AGM) of the Developing Countries Vaccine Manufacturers' Network (DCVMN). Contributions of Gavi and the vaccine industry from emerging countries to the growing global vaccine market, by improving the supply base from manufacturers in developing countries and contributing to 58% of doses, were highlighted. The Coalition for Epidemic Preparedness Innovations (CEPI), the International Vaccine Institute (IVI) and others reported on new strategies to ensure speedy progress in preclinical and clinical development of innovative vaccines for future MERS, Zika or other outbreak response. Priorities for vaccine stockpiling, to assure readiness during emergencies and to prevent outbreaks due to re-emerging diseases such as yellow fever, cholera and poliomyelitis, were outlined. The role of partnerships in improving global vaccine access, procurement and immunization coverage, and shared concerns were reviewed. The World Health Organization (WHO) and other international collaborating partners provided updates on the Product, Price and Procurement database, the prequalification of vaccines, the control of neglected tropical diseases, particularly the new rabies elimination initiative, and regulatory convergence proposals to accelerate vaccine registration in developing countries. Updates on supply chain innovations and novel vaccine platforms were presented. The discussions enabled members and partners to reflect on efficiency of research & development, supply chain tools and trends in packaging technologies improving delivery of existing vaccines, and allowing a deeper understanding of the current public-health objectives, industry financing, and global policies, required to ensure optimal investments, alignment and stability of vaccine supply in developing countries. Copyright © 2018. Published by Elsevier Ltd.

Technology transfer of oil-in-water emulsion adjuvant manufacturing for pandemic influenza vaccine production in Romania: Preclinical evaluation of split virion inactivated H5N1 vaccine with adjuvant.

PubMed

Stavaru, Crina; Onu, Adrian; Lupulescu, Emilia; Tucureanu, Catalin; Rasid, Orhan; Vlase, Ene; Coman, Cristin; Caras, Iuliana; Ghiorghisor, Alina; Berbecila, Laurentiu; Tofan, Vlad; Bowen, Richard A; Marlenee, Nicole; Hartwig, Airn; Bielefeldt-Ohmann, Helle; Baldwin, Susan L; Van Hoeven, Neal; Vedvick, Thomas S; Huynh, Chuong; O'Hara, Michael K; Noah, Diana L; Fox, Christopher B

2016-04-02

Millions of seasonal and pandemic influenza vaccine doses containing oil-in-water emulsion adjuvant have been administered in order to enhance and broaden immune responses and to facilitate antigen sparing. Despite the enactment of a Global Action Plan for Influenza Vaccines and a multi-fold increase in production capabilities over the past 10 years, worldwide capacity for pandemic influenza vaccine production is still limited. In developing countries, where routine influenza vaccination is not fully established, additional measures are needed to ensure adequate supply of pandemic influenza vaccines without dependence on the shipment of aid from other, potentially impacted first-world countries. Adaptation of influenza vaccine and adjuvant technologies by developing country influenza vaccine manufacturers may enable antigen sparing and corresponding increases in global influenza vaccine coverage capacity. Following on previously described work involving the technology transfer of oil-in-water emulsion adjuvant manufacturing to a Romanian vaccine manufacturing institute, we herein describe the preclinical evaluation of inactivated split virion H5N1 influenza vaccine with emulsion adjuvant, including immunogenicity, protection from virus challenge, antigen sparing capacity, and safety. In parallel with the evaluation of the bioactivity of the tech-transferred adjuvant, we also describe the impact of concurrent antigen manufacturing optimization activities. Depending on the vaccine antigen source and manufacturing process, inclusion of adjuvant was shown to enhance and broaden functional antibody titers in mouse and rabbit models, promote protection from homologous virus challenge in ferrets, and facilitate antigen sparing. Besides scientific findings, the operational lessons learned are delineated in order to facilitate adaptation of adjuvant technologies by other developing country institutes to enhance global pandemic influenza preparedness.

Development of a Low Cost Microcontroller-Enabled Handheld Sunphotometer and Comparison with NASA AERONET and MODIS

NASA Astrophysics Data System (ADS)

Krintz, I. A.; Ruble, W.; Sherman, J. P.

2017-12-01

Satellite-based measurements of aerosol optical depth (AOD), such as those made by NASA's Moderate Resolution Imaging Spectroradiometer (MODIS) aboard the TERRA and AQUA spacecraft, are often used in studies of aerosol direct radiative forcing (DRF) on regional to global scales due to daily near-global coverage. However, these measurements require validation by ground-based instrumentation, which is limited due to the cost of research-grade instrumentation. Furthermore, satellite-based AOD agreement with "ground-truth" instruments is weaker over mountainous regions (Levy et al., 2010). To aid in satellite validation, a low cost handheld sunphotometer has been developed which will be suitable for deployment to multiple sites to form a citizen science network as part of an upcoming proposal. A microcontroller, along with temperature and pressure sensors, has been included in this design to ease the process of taking measurements and transferring data for processing. Although LED-based sunphotometers have been used for a number of years (Brooks and Mims, 2001), this design uses filtered photodiodes which appear to have less of a temperature dependence. The interface has been designed to be intuitive to citizen scientists of all ages, nationalities, and backgrounds, so that deployment to primary schools and international sites will be as seamless as possible. Presented here is the instrument design, as well as initial results of a comparison with NASA Aerosol Robotic Network (AERONET) and MODIS-measured AOD. Future revisions to the instrument design, such as incorporation of surface-mount devices to cut down on circuit board size, will allow for an even smaller and more cost effective solution suitable for a global sunphotometer network.

Remote Sensing of Cloud, Aerosol, and Land Properties from MODIS: Applications to the East Asia Region

NASA Technical Reports Server (NTRS)

King, Michael D.; Platnick, Steven; Chu, D. Allen; Moody, Eric G.

2001-01-01

MODIS is an earth-viewing cross-track scanning spectroradiometer launched on the Terra satellite in December 1999. MODIS scans a swath width sufficient to provide nearly complete global coverage every two days from a polar-orbiting, sun-synchronous platform at an altitude of 705 km, and provides images in 36 spectral bands between 0.415 and 14.235 microns with spatial resolutions of 250 m (two bands), 500 m (five bands) and 1000 m (29 bands). These bands have been carefully selected to enable advanced studies of land, ocean, and atmospheric processes. In this presentation we review the comprehensive set of remote sensing algorithms that have been developed for the remote sensing of atmospheric properties using MODIS data, placing primary emphasis on the principal atmospheric applications of (i) developing a cloud mask for distinguishing clear sky from clouds, (ii) retrieving global cloud radiative and microphysical properties, including cloud top pressure and temperature, effective emissivity, cloud optical thickness, thermodynamic phase, and effective radius, (iii) monitoring tropospheric aerosol optical thickness over the land and ocean and aerosol size distribution over the ocean, (iv) determining atmospheric profiles of moisture and temperature, and (v) estimating column water amount. The physical principles behind the determination of each of these atmospheric products will be described, together with an example of their application using MODIS observations to the east Asian region in Spring 2001. All products are archived into two categories: pixel-level retrievals (referred to as Level-2 products) and global gridded products at a latitude and longitude resolution of 1 degree (Level-3 products). An overview of the MODIS atmosphere algorithms and products, status, validation activities, and early level-2 and -3 results will be presented.

Remote Sensing of Cloud, Aerosol, and Water Vapor Properties from MODIS

NASA Technical Reports Server (NTRS)

King, Michael D.; Platnick, Steven; Menzel, W. Paul; Kaufman, Yoram J.; Ackerman, Steven A.; Tanre, Didier; Gao, Bo-Cai

2001-01-01

MODIS is an earth-viewing cross-track scanning spectroradiometer launched on the Terra satellite in December 1999. MODIS scans a swath width sufficient to provide nearly complete global coverage every two days from a polar orbiting, sun-synchronous, platform at an altitude of 705 kilometers, and provides images in 36 spectral bands between 0.415 and 14.235 micrometers with spatial resolutions of 250 meters (2 bands), 500 meters (5 bands) and 1000 meters (29 bands). These bands have been carefully selected to enable advanced studies of land, ocean, and atmospheric processes. In this presentation we review the comprehensive set of remote sensing algorithms that have been developed for the remote sensing of atmospheric properties using MODIS data, placing primary emphasis on the principal atmospheric applications of (i) developing a cloud mask for distinguishing clear sky from clouds, (ii) retrieving global cloud radiative and microphysical properties, including cloud top pressure and temperature, effective emissivity, cloud optical thickness, thermodynamic phase, and effective radius, (iii) monitoring tropospheric aerosol optical thickness over the land and ocean and aerosol size distribution over the ocean, (iv) determining atmospheric profiles of moisture and temperature, and (v) estimating column water amount. The physical principles behind the determination of each of these atmospheric products will be described, together with an example of their application using MODIS observations. All products are archived into two categories: pixel-level retrievals (referred to as Level-2 products) and global gridded products at a latitude and longitude resolution of 1 degree (Level-3 products). An overview of the MODIS atmosphere algorithms and products, status, validation activities, and early level-2 and -3 results will be presented.

Accuracy of Coverage Survey Recall following an Integrated Mass Drug Administration for Lymphatic Filariasis, Schistosomiasis, and Soil-Transmitted Helminthiasis.

PubMed

Budge, Philip J; Sognikin, Edmond; Akosa, Amanda; Mathieu, Els M; Deming, Michael

2016-01-01

Achieving target coverage levels for mass drug administration (MDA) is essential to elimination and control efforts for several neglected tropical diseases (NTD). To ensure program goals are met, coverage reported by drug distributors may be validated through household coverage surveys that rely on respondent recall. This is the first study to assess accuracy in such surveys. Recall accuracy was tested in a series of coverage surveys conducted at 1, 6, and 12 months after an integrated MDA in Togo during which three drugs (albendazole, ivermectin, and praziquantel) were distributed. Drug distribution was observed during the MDA to ensure accurate recording of persons treated during the MDA. Information was obtained for 506, 1131, and 947 persons surveyed at 1, 6, and 12 months, respectively. Coverage (defined as the percentage of persons taking at least one of the MDA medications) within these groups was respectively 88.3%, 87.4%, and 80.0%, according to the treatment registers; it was 87.9%, 91.4% and 89.4%, according to survey responses. Concordance between respondents and registers on swallowing at least one pill was >95% at 1 month and >86% at 12 months; the lower concordance at 12 months was more likely due to difficulty matching survey respondents with the year-old treatment register rather than inaccurate responses. Respondents generally distinguished between pills similar in appearance; concordance for recall of which pills were taken was over 80% in each survey. In this population, coverage surveys provided remarkably consistent coverage estimates for up to one year following an integrated MDA. It is not clear if similar consistency will be seen in other settings, however, these data suggest that in some settings coverage surveys might be conducted as much as one year following an MDA without compromising results. This might enable integration of post-MDA coverage measurement into large, multipurpose, periodic surveys, thereby conserving resources.

Accuracy of Coverage Survey Recall following an Integrated Mass Drug Administration for Lymphatic Filariasis, Schistosomiasis, and Soil-Transmitted Helminthiasis

PubMed Central

Budge, Philip J.; Sognikin, Edmond; Akosa, Amanda; Mathieu, Els M.; Deming, Michael

2016-01-01

Background Achieving target coverage levels for mass drug administration (MDA) is essential to elimination and control efforts for several neglected tropical diseases (NTD). To ensure program goals are met, coverage reported by drug distributors may be validated through household coverage surveys that rely on respondent recall. This is the first study to assess accuracy in such surveys. Methodology/Principal Findings Recall accuracy was tested in a series of coverage surveys conducted at 1, 6, and 12 months after an integrated MDA in Togo during which three drugs (albendazole, ivermectin, and praziquantel) were distributed. Drug distribution was observed during the MDA to ensure accurate recording of persons treated during the MDA. Information was obtained for 506, 1131, and 947 persons surveyed at 1, 6, and 12 months, respectively. Coverage (defined as the percentage of persons taking at least one of the MDA medications) within these groups was respectively 88.3%, 87.4%, and 80.0%, according to the treatment registers; it was 87.9%, 91.4% and 89.4%, according to survey responses. Concordance between respondents and registers on swallowing at least one pill was >95% at 1 month and >86% at 12 months; the lower concordance at 12 months was more likely due to difficulty matching survey respondents with the year-old treatment register rather than inaccurate responses. Respondents generally distinguished between pills similar in appearance; concordance for recall of which pills were taken was over 80% in each survey. Significance In this population, coverage surveys provided remarkably consistent coverage estimates for up to one year following an integrated MDA. It is not clear if similar consistency will be seen in other settings, however, these data suggest that in some settings coverage surveys might be conducted as much as one year following an MDA without compromising results. This might enable integration of post-MDA coverage measurement into large, multipurpose, periodic surveys, thereby conserving resources. PMID:26766287

Protecting Important Sites for Biodiversity Contributes to Meeting Global Conservation Targets

PubMed Central

Butchart, Stuart H. M.; Scharlemann, Jörn P. W.; Evans, Mike I.; Quader, Suhel; Aricò, Salvatore; Arinaitwe, Julius; Balman, Mark; Bennun, Leon A.; Bertzky, Bastian; Besançon, Charles; Boucher, Timothy M.; Brooks, Thomas M.; Burfield, Ian J.; Burgess, Neil D.; Chan, Simba; Clay, Rob P.; Crosby, Mike J.; Davidson, Nicholas C.; De Silva, Naamal; Devenish, Christian; Dutson, Guy C. L.; Fernández, David F. Día z; Fishpool, Lincoln D. C.; Fitzgerald, Claire; Foster, Matt; Heath, Melanie F.; Hockings, Marc; Hoffmann, Michael; Knox, David; Larsen, Frank W.; Lamoreux, John F.; Loucks, Colby; May, Ian; Millett, James; Molloy, Dominic; Morling, Paul; Parr, Mike; Ricketts, Taylor H.; Seddon, Nathalie; Skolnik, Benjamin; Stuart, Simon N.; Upgren, Amy; Woodley, Stephen

2012-01-01

Protected areas (PAs) are a cornerstone of conservation efforts and now cover nearly 13% of the world's land surface, with the world's governments committed to expand this to 17%. However, as biodiversity continues to decline, the effectiveness of PAs in reducing the extinction risk of species remains largely untested. We analyzed PA coverage and trends in species' extinction risk at globally significant sites for conserving birds (10,993 Important Bird Areas, IBAs) and highly threatened vertebrates and conifers (588 Alliance for Zero Extinction sites, AZEs) (referred to collectively hereafter as ‘important sites’). Species occurring in important sites with greater PA coverage experienced smaller increases in extinction risk over recent decades: the increase was half as large for bird species with>50% of the IBAs at which they occur completely covered by PAs, and a third lower for birds, mammals and amphibians restricted to protected AZEs (compared with unprotected or partially protected sites). Globally, half of the important sites for biodiversity conservation remain unprotected (49% of IBAs, 51% of AZEs). While PA coverage of important sites has increased over time, the proportion of PA area covering important sites, as opposed to less important land, has declined (by 0.45–1.14% annually since 1950 for IBAs and 0.79–1.49% annually for AZEs). Thus, while appropriately located PAs may slow the rate at which species are driven towards extinction, recent PA network expansion has under-represented important sites. We conclude that better targeted expansion of PA networks would help to improve biodiversity trends. PMID:22457717

Gaps in health insurance: why so many Americans experience breaks in coverage and how the Affordable Care Act will help: findings from the Commonwealth Fund Health Insurance Tracking Survey of U.S. Adults, 2011.

PubMed

Collins, Sara R; Robertson, Ruth; Garber, Tracy; Doty, Michelle M

2012-04-01

The Commonwealth Fund Health Insurance Tracking Survey of U.S. Adults finds that one-quarter of adults ages 19 to 64 experienced a gap in their health insurance in 2011, with a majority remaining uninsured for one year or more. Losing or changing jobs was the primary reason people experienced a gap. Compared with adults who had continuous coverage, those who experienced gaps were less likely to have a regular doctor and less likely to be up to date with recommended preventive care tests, with rates declining as the length of the coverage gap increases. Early provisions of the Affordable Care Act are already helping bridge gaps in coverage among young adults and people with preexisting conditions. Beginning in 2014, new affordable health insurance options through Medicaid and state insurance exchanges will enable adults and their families to remain insured even in the face of job changes and other life disruptions.

Trends in AIDS Deaths, New Infections and ART Coverage in the Top 30 Countries with the Highest AIDS Mortality Burden; 1990–2013

PubMed Central

Granich, Reuben; Gupta, Somya; Hersh, Bradley; Williams, Brian; Montaner, Julio; Young, Benjamin; Zuniga, José M.

2015-01-01

Background Antiretroviral therapy (ART) prevents human immunodeficiency virus (HIV) disease progression, mortality and transmission. We assess the impact of expanded HIV treatment for the prevention of Acquired Immunodeficiency Syndrome (AIDS)-related deaths and simulate four treatment scenarios for Nigeria and South Africa. Methods For 1990–2013, we used the Joint United Nations Programme on HIV/AIDS (UNAIDS) database to examine trends in AIDS deaths, HIV incidence and prevalence, ART coverage, annual AIDS death rate, AIDS death-to-treatment and HIV infections to treatment ratios for the top 30 countries with the highest AIDS mortality burden and compare them with data from high-income countries. We projected the 1990–2020 AIDS deaths for Nigeria and South Africa using four treatment scenarios: 1) no ART; 2) maintaining current ART coverage; 3) 90% ART coverage based on 2013 World Health Organization (WHO) ART guidelines by 2020; and 4) reaching the United Nations 90-90-90 Target by 2020. Findings In 2013, there were 1.3 million (1.1 million–1.6 million) AIDS deaths in the top 30 countries representing 87% of global AIDS deaths. Eight countries accounted for 58% of the global AIDS deaths; Nigeria and South Africa accounted for 27% of global AIDS deaths. The highest death rates per 1000 people living with HIV were in Central African Republic (91), South Sudan (82), Côte d’Ivoire (75), Cameroon (72) and Chad (71), nearly 8–10 times higher than the high-income countries. ART access in 2013 has averted as estimated 1,051,354 and 422,448 deaths in South Africa and Nigeria, respectively. Increasing ART coverage in these two countries to meet the proposed UN 90-90-90 Target by 2020 could avert 2.2 and 1.2 million deaths, respectively. Interpretation Over the past decade the expansion of access to ART averted millions of deaths. Reaching the proposed UN 90-90-90 Target by 2020 will prevent additional morbidity, mortality and HIV transmission. Despite progress, high-burden countries will need to accelerate access to ART treatment to avert millions of premature AIDS deaths and new HIV infections. PMID:26147987

Employer-sponsored health insurance in New York: findings from the 2003 Commonwealth Fund/HRET survey.

PubMed

Edwards, Jennifer N; How, Sabrina; Whitmore, Heidi; Gabel, Jon R; Hawkins, Samantha; Pickreign, Jeremy D

2004-05-01

A 2003 Commonwealth Fund/Health Research and Educational Trust survey of 576 New York State firms found that, in order to manage rising health costs, employers are increasing the share of the insurance premium that employees pay, delaying the start of benefits, and increasing cost-sharing at the point of service. This has enabled employers to preserve health benefits, but has raised costs for workers and their families. On average, workers' contributions for family coverage rose 54 percent, from $1,392 per year in 2001 to $2,148 per year in 2003. During that time period, fewer workers selected family coverage. Employers are receptive to a wide range of approaches to make coverage more available and affordable for their employees, but they have limited familiarity with public programs that could cover their lower-wage workers, such as Healthy New York, Family Health Plus, or Child Health Plus.

75 FR 27649 - 2010 Annual Determination for Sea Turtle Observer Requirements

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-18

... enable the design of an appropriate sampling program and to ensure collection of sufficient scientific... Observer Coverage in a Fishery Listed on the 2010 Annual Determination The design of any observer program.... During the program design, NMFS will be guided by the following standards for distributing and placing...

Agencies collaborate, develop a cyanobacteria assessment network

USGS Publications Warehouse

Schaeffer, Blake A.; Loftin, Keith A.; Stumpf, Richard P.; Werdell, P. Jeremy

2015-01-01

Satellite remote sensing tools may enable policy makers and environmental managers to assess the sustainability of watershed ecosystems and the services they provide, now and in the future. Satellite technology allows us to develop early-warning indicators of cyanobacteria blooms at the local scale while maintaining continuous national coverage.

Standards Handbook. Version 4.0. What Works Clearinghouse™

ERIC Educational Resources Information Center

What Works Clearinghouse, 2017

2017-01-01

The What Works Clearinghouse (WWC) systematic review process is the basis of many of its products, enabling the WWC to use consistent, objective, and transparent standards and procedures in its reviews, while also ensuring comprehensive coverage of the relevant literature. The WWC systematic review process consists of five steps: (1) Developing…

Internet of Things

ERIC Educational Resources Information Center

Ritz, John; Knaack, Zane

2017-01-01

In the 21st century, electronic connectivity is a major component of everyday life. One expects to have mobile phone coverage and to have access to log a computer or tablet onto the internet. This connectivity enables users to keep track of personal affairs and conduct work from remote locations. Designers and manufacturers are also connecting…

Experiences and Lessons From Polio Eradication Applied to Immunization in 10 Focus Countries of the Polio Endgame Strategic Plan.

PubMed

van den Ent, Maya M V X; Mallya, Apoorva; Sandhu, Hardeep; Anya, Blanche-Philomene; Yusuf, Nasir; Ntakibirora, Marcelline; Hasman, Andreas; Fahmy, Kamal; Agbor, John; Corkum, Melissa; Sumaili, Kyandindi; Siddique, Anisur Rahman; Bammeke, Jane; Braka, Fiona; Andriamihantanirina, Rija; Ziao, Antoine-Marie C; Djumo, Clement; Yapi, Moise Desire; Sosler, Stephen; Eggers, Rudolf

2017-07-01

Nine polio areas of expertise were applied to broader immunization and mother, newborn and child health goals in ten focus countries of the Polio Eradication Endgame Strategic Plan: policy & strategy development, planning, management and oversight (accountability framework), implementation & service delivery, monitoring, communications & community engagement, disease surveillance & data analysis, technical quality & capacity building, and partnerships. Although coverage improvements depend on multiple factors and increased coverage cannot be attributed to the use of polio assets alone, 6 out of the 10 focus countries improved coverage in three doses of diphtheria tetanus pertussis containing vaccine between 2013 and 2015. Government leadership, evidence-based programming, country-driven comprehensive operational annual plans, community partnership and strong accountability systems are critical for all programs and polio eradication has illustrated these can be leveraged to increase immunization coverage and equity and enhance global health security in the focus countries. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.

A Relationship Between Visible and Near-IR Global Spectral Reflectance based on DSCOVR/EPIC

NASA Astrophysics Data System (ADS)

Wen, G.; Marshak, A.; Song, W.; Knyazikhin, Y.

2017-12-01

The launch of Deep Space Climate Observatory (DSCOVR) to the Earth's first Lagrange point (L1) allows us to see a new perspective of the Earth. The Earth Polychromatic Imaging Camera (EPIC) on the DSCOVR measures the back scattered radiation of the entire sunlit side of the Earth at 10 narrow band wavelengths ranging from ultraviolet to visible and near-infrared. We analyzed EPIC global averaged reflectance data. We found that the global averaged visible reflectance has a unique non-linear relationship with near infrared (NIR) reflectance. This non-linear relationship was not observed by any other satellite observations due to a limited spatial and temporal coverage of either low earth orbit (LEO) or geostationary satellite. The non-linear relationship is associated with the changing in the coverages of ocean, cloud, land, and vegetation as the Earth rotates. We used Terra and Aqua MODIS daily global radiance data to simulate EPIC observations. Since MODIS samples the Earth in a limited swath (2330km cross track) at a specific local time (10:30 am for Terra, 1:30 pm for Aqua) with approximately 15 orbits per day, the global average reflectance at a given time may be approximated by averaging the reflectance in the MODIS nearest-time swaths in the sunlit hemisphere. We found that MODIS simulated global visible and NIR spectral reflectance captured the major feature of the EPIC observed non-linear relationship with some errors. The difference between the two is mainly due to the sampling limitation of polar satellite. This suggests that that EPIC observations can be used to reconstruct MODIS global average reflectance time series for studying Earth system change in the past decade.

New Science Opportunities on COSMIC-2/FORMOSAT-7

NASA Technical Reports Server (NTRS)

Mannucci, Anthony J.; Meehan, Thomas K.; Lowe, Stephen T.; Ao, Chi O; Franklin, Garth; Pi, Xiaoqing; Young, Lawrence E.; Kuo, Ying-Hwa (Bill); Schreiner, William S.

2013-01-01

COSMIC-2 Polar (second launch) is an excellent opportunity to extend SSAEM capabilities to global coverage. Enhanced ionospheric remote sensing via oceanic TEC and DORIS. Science: lower-upper atmosphere coupling. Additional payloads are being considered by NSPO/Taiwan.

Map of Rhea - January 2011

NASA Image and Video Library

2011-05-02

This global digital map of Rhea was created using data taken during NASA Cassini and Voyager spacecraft flybys. This map contains data from Cassini Jan. 11, 2011, flyby of Rhea. Six Voyager images fill gaps in Cassini coverage of the north pole.

High Spatial Resolution Europa Coverage by the Galileo Near Infrared Mapping Spectrometer NIMS

NASA Image and Video Library

1998-03-26

NASA Galileo spacecraft, which was used to map the mineral and ice properties over the surfaces of the Jovian moons, producing global spectral images for small selected regions on the satellites in 1996-97.

Synergistic Opportunities for the Geostationary Satellite Constellation: Status of the CEOS Activity

NASA Astrophysics Data System (ADS)

Al-Saadi, J. A.; Zehner, C.

2012-12-01

This talk will summarize activities of the Committee on Earth Observation Satellites (CEOS) Atmospheric Composition Constellation (ACC) to collaboratively advance the next generation of air quality monitoring from space. Over the past 2 years, CEOS ACC have developed a position paper describing the benefits to be derived from such collaboration. The resulting ACC recommendations were endorsed by CEOS in May 2011. We will discuss next steps toward implementing this vision, starting with a new 3-year CEOS Action in 2012. Several countries and space agencies are currently planning to launch geostationary Earth orbit (GEO) missions in 2017-2022 to obtain atmospheric composition measurements for characterizing anthropogenic and natural distributions of tropospheric ozone, aerosols, and their precursors. These missions include Europe's ESA Sentinel-4 with EUMETSAT IRS, the United States' NASA GEO-CAPE, Korea's ME/MEST/KARI GEMS, and Japan's JAXA GMAP-Asia. GEO observations offer a quantum advance in air quality monitoring from space by providing measurements many times per day. However, a single GEO satellite views only a portion of the globe. These satellites, positioned to view Europe, East Asia, and North America, will collectively provide hourly coverage of the industrialized Northern Hemisphere at similar spatial resolutions. Planned low Earth orbit (LEO) missions will provide complementary daily global observations. Observations from a single LEO satellite will overlap those from each GEO satellite once per day, providing a means for combining the GEO observations and a necessary perspective for interpreting global impacts of smaller scale processes. The EUMETSAT Metop series, NOAA/NASA JPSS series, and ESA Sentinel-5 Precursor and Sentinel-5 missions will each provide such daily overlap with the GEO missions. The Canadian PCW PHEMOS mission will make an additional unique suite of observations. PCW will provide quasi-geostationary coverage over the Arctic that overlaps with each geostationary satellite over 30N - 60N, adding opportunities for intercalibration many times per day. The development of common data products, data distribution protocols, and calibration strategies will synergistically enable critically needed understanding of the interactions between regional and global atmospheric composition. Common air quality trace gas products will be tropospheric column O3, NO2, HCHO, and SO2 nominally at 8 km spatial resolution and 1 hour temporal frequency. Detection of aerosols in the UV will allow absorbing aerosols to be distinguished from total aerosol optical depth, providing information on aerosol speciation and particularly relevant to the air quality/climate interface associated with aerosol radiative forcing. Such activities directly address societal benefit areas of the Global Earth Observation System of Systems (GEOSS), including Health, Energy, Climate, Disasters, and Ecosystems, and are responsive to the requirements of each mission to provide advanced user services and societal benefits in their own regions.

Transforming Reserve Officers’ Training Corps for Tomorrow’s Officer

DTIC Science & Technology

2013-03-01

unit leadership failures at places like Abu Ghraib and the March 2012 slaying of 16 Afghan civilians by Staff Sgt. Robert Bales received global media ...coverage. These incidents highlight how poor judgment at the small unit level, magnified by the global media , can affect world opinion. Army...require the combined mass of brigades, divisions, and corps.Ś Regardless the threat or location, the squad and small unit formation will remain the

Predicting present-day rates of glacial isostatic adjustment using a smoothed GPS velocity field for the reconciliation of NAD83 reference frames in Canada

NASA Astrophysics Data System (ADS)

Craymer, M. R.; Henton, J. A.; Piraszewski, M.

2008-12-01

Glacial isostatic adjustment following the last glacial period is the dominant source of crustal deformation in Canada east of the Rocky Mountains. The present-day vertical component of motion associated with this process may exceed 1 cm/y and is being directly measured with the Global Positioning System (GPS). A consequence of this steady deformation is that high accuracy coordinates at one epoch may not be compatible with those at another epoch. For example, modern precise point positioning (PPP) methods provide coordinates at the epoch of observation while NAD83, the officially adopted reference frame in Canada and the U.S., is expressed at some past reference epoch. The PPP positions are therefore incompatible with coordinates in such a realization of the reference frame and need to be propagated back to the frame's reference epoch. Moreover, the realizations of NAD83 adopted by the provincial geodetic agencies in Canada are referenced to different coordinate epochs; either 1997.0 or 2002.0. Proper comparison of coordinates between provinces therefore requires propagating them from one reference epoch to another. In an effort to reconcile PPP results and different realizations of NAD83, we empirically represent crustal deformation throughout Canada using a velocity field based solely on high accuracy continuous and episodic GPS observations. The continuous observations from 2001 to 2007 were obtained from nearly 100 permanent GPS stations, predominately operated by Natural Resources Canada (NRCan) and provincial geodetic agencies. Many of these sites are part of the International GNSS Service (IGS) global network. Episodic observations from 1994 to 2006 were obtained from repeated occupations of the Canadian Base Network (CBN), which consists of approximately 160 stable pillar-type monuments across the entire country. The CBN enables a much denser spatial sampling of crustal motions although coverage in the far north is still rather sparse. NRCan solutions of the continuous GPS data were combined with those from other agencies as part of the North American Reference Frame (NAREF) effort to improve the reliability of the results. This NAREF solution has then been combined with our CBN results to obtain a denser velocity sampling for fitting different types of surfaces in a first attempt to determine a continuous GPS velocity field for the entire country. Expressing this velocity field as a grid enables users to interpolate to any location in Canada, allowing for the propagation of coordinates to any desired reference epoch. We examine the accuracy and limitations of this GPS velocity field by comparing it to other published GPS velocity solutions (which are all based on less data) as well as to GIA models, including versions of ICE-3G, ICE-5G and the recent Stable North America Reference Frame (SNARF) model. Of course, the accuracy of the GPS velocity field depends directly on the density of the GPS coverage. Consequently, the GPS velocity field is unable to fully represent the actual GIA motion in the far north and tends to smooth out the signal due to the spatially sparse coverage. On the other hand, the model performs quite well in the southern parts of the country where there is a much greater spatial density of GPS measurements.

Global distribution and surface activity of macromolecules in offline simulations of marine organic chemistry

DOE PAGES

Ogunro, Oluwaseun O.; Burrows, Susannah M.; Elliott, Scott; ...

2015-10-13

Here, organic macromolecules constitute high percentage components of remote sea spray. They enter the atmosphere through adsorption onto bubbles followed by bursting at the ocean surface, and go on to influence the chemistry of the fine mode aerosol. We present a global estimate of mixed-layer organic macromolecular distributions, driven by offline marine systems model output. The approach permits estimation of oceanic concentrations and bubble film surface coverages for several classes of organic compound. Mixed layer levels are computed from the output of a global ocean biogeochemistry model by relating the macromolecules to standard biogeochemical tracers. Steady state is assumed formore » labile forms, and for longer-lived components we rely on ratios to existing transported variables. Adsorption is then represented through conventional Langmuir isotherms, with equilibria deduced from laboratory analogs. Open water concentrations locally exceed one micromolar carbon for the total of protein, polysaccharide and refractory heteropolycondensate. The shorter-lived lipids remain confined to regions of strong biological activity. Results are evaluated against available measurements for all compound types, and agreement is generally quite reasonable. Global distributions are further estimated for both fractional coverage of bubble films at the air-water interface and the two-dimensional concentration excess. Overall, we show that macromolecular mapping provides a novel tool for the comprehension of oceanic surfactant distributions. Results may prove useful in planning field experiments and assessing the potential response of surface chemical behaviors to global change.« less

Remote Sensing of Cloud, Aerosol, and Water Vapor Properties from MODIS

NASA Technical Reports Server (NTRS)

King, Michael D.

2001-01-01

MODIS is an earth-viewing cross-track scanning spectroradiometer launched on the Terra satellite in December 1999. MODIS scans a swath width sufficient to provide nearly complete global coverage every two days from a polar-orbiting, sun-synchronous, platform at an altitude of 705 km, and provides images in 36 spectral bands from 0.415 to 14.235 microns with spatial resolutions of 250 m (2 bands), 500 m (5 bands) and 1000 m (29 bands). These bands have been carefully selected to enable advanced studies of land, ocean, and atmospheric processes. In this presentation I will review the comprehensive set of remote sensing algorithms that have been developed for the remote sensing of atmospheric properties using MODIS data, placing primary emphasis on the principal atmospheric applications of: (1) developing a cloud mask for distinguishing clear sky from clouds, (2) retrieving global cloud radiative and microphysical properties, including cloud top pressure and temperature, effective emissivity, cloud optical thickness, thermodynamic phase, and effective radius, (3) monitoring tropospheric aerosol optical thickness over the land and ocean and aerosol size distribution over the ocean, (4) determining atmospheric profiles of moisture and temperature, and (5) estimating column water amount. The physical principles behind the determination of each of these atmospheric products will be described, together with an example of their application using MODIS observations. All products are archived into two categories: pixel-level retrievals (referred to as Level-2 products) and global gridded products at a latitude and longitude resolution of 1 deg (Level-3 products). An overview of the MODIS atmosphere algorithms and products, status, validation activities, and early level-2 and -3 results will be presented. Finally, I will present some highlights from the land and ocean algorithms developed for processing global MODIS observations, including: (1) surface reflectance, (2) vegetation indices, leaf area index, and FPAR, (3) albedo and nadir BRDF-adjusted reflectance, (4) normalized water-leaving radiance, (5) chlorophyll-a concentration, and (6) sea surface temperature.

International river basins of the world

USGS Publications Warehouse

Wolf, Aaron T.; Natharius, Jeffrey A.; Danielson, Jeffrey J.; Ward, Brian S.; Pender, Jan K.

1999-01-01

It is becoming acknowledged that water is likely to be the most pressing environmental concern of the next century. Difficulties in river basin management are only exacerbated when the resource crosses international boundaries. One critical aid in the assessment of international waters has been the Register of International Rivers a compendium which listed 214 international waterways that cover 47% of the earth's continental land surface. The Register, though, was last updated in 1978 by the now defunct United Nations Department of Economic and Social Affairs. The purpose of this paper is to update the Register in order to reflect the quantum changes that have taken place over the last 22 years, both in global geopolitics and in map coverage and technology. By accessing digital elevation models at spatial resolutions of 30 arc seconds, corroborating at a unified global map coverage of at least 1:1 000 000, and superimposing the results over complete coverage of current political boundaries, we are able to provide a new register which lists 261 international rivers, covering 45.3% of the land surface of the earth (excluding Antarctica). This paper lists all international rivers with their watershed areas, the nations which share each watershed,their respective territorial percentages, and notes on changes in or disputes over international boundaries since 1978.

Global warming not so harmful for all plants - response of holomycotrophic orchid species for the future climate change.

PubMed

Kolanowska, Marta; Kras, Marta; Lipińska, Monika; Mystkowska, Katarzyna; Szlachetko, Dariusz L; Naczk, Aleksandra M

2017-10-05

Current and expected changes in global climate are major threat for biological diversity affecting individuals, communities and ecosystems. However, there is no general trend in the plants response to the climate change. The aim of present study was to evaluate impact of the future climate changes on the distribution of holomycotrophic orchid species using ecological niche modeling approach. Three different scenarios of future climate changes were tested to obtain the most comprehensive insight in the possible habitat loss of 16 holomycotrophic orchids. The extinction of Cephalanthera austiniae was predicted in all analyses. The coverage of suitable niches of Pogoniopsis schenckii will decrease to 1-30% of its current extent. The reduction of at least 50% of climatic niche of Erythrorchis cassythoides and Limodorum abortivum will be observed. In turn, the coverage of suitable niches of Hexalectris spicata, Uleiorchis ulaei and Wullschlaegelia calcarata may be even 16-74 times larger than in the present time. The conducted niche modeling and analysis of the similarity of their climatic tolerance showed instead that the future modification of the coverage of their suitable niches will not be unified and the future climate changes may be not so harmful for holomycotrophic orchids as expected.

Multiscale site-response mapping: A case study of Parkfield, California

USGS Publications Warehouse

Thompson, E.M.; Baise, L.G.; Kayen, R.E.; Morgan, E.C.; Kaklamanos, J.

2011-01-01

The scale of previously proposed methods for mapping site-response ranges from global coverage down to individual urban regions. Typically, spatial coverage and accuracy are inversely related.We use the densely spaced strong-motion stations in Parkfield, California, to estimate the accuracy of different site-response mapping methods and demonstrate a method for integrating multiple site-response estimates from the site to the global scale. This method is simply a weighted mean of a suite of different estimates, where the weights are the inverse of the variance of the individual estimates. Thus, the dominant site-response model varies in space as a function of the accuracy of the different models. For mapping applications, site-response models should be judged in terms of both spatial coverage and the degree of correlation with observed amplifications. Performance varies with period, but in general the Parkfield data show that: (1) where a velocity profile is available, the square-rootof- impedance (SRI) method outperforms the measured VS30 (30 m divided by the S-wave travel time to 30 m depth) and (2) where velocity profiles are unavailable, the topographic slope method outperforms surficial geology for short periods, but geology outperforms slope at longer periods. We develop new equations to estimate site response from topographic slope, derived from the Next Generation Attenuation (NGA) database.

Moving towards universal coverage in South Africa? Lessons from a voluntary government insurance scheme.

PubMed

Govender, Veloshnee; Chersich, Matthew F; Harris, Bronwyn; Alaba, Olufunke; Ataguba, John E; Nxumalo, Nonhlanhla; Goudge, Jane

2013-01-24

In 2005, the South African government introduced a voluntary, subsidised health insurance scheme for civil servants. In light of the global emphasis on universal coverage, empirical evidence is needed to understand the relationship between new health financing strategies and health care access thereby improving global understanding of these issues. This study analysed coverage of the South African government health insurance scheme, the population groups with low uptake, and the individual-level factors, as well as characteristics of the scheme, that influenced enrolment. Multi-stage random sampling was used to select 1,329 civil servants from the health and education sectors in four of South Africa's nine provinces. They were interviewed to determine factors associated with enrolment in the scheme. The analysis included both descriptive statistics and multivariate logistic regression. Notwithstanding the availability of a non-contributory option within the insurance scheme and access to privately-provided primary care, a considerable portion of socio-economically vulnerable groups remained uninsured (57.7% of the lowest salary category). Non-insurance was highest among men, black African or coloured ethnic groups, less educated and lower-income employees, and those living in informal-housing. The relatively poor uptake of the contributory and non-contributory insurance options was mostly attributed to insufficient information, perceived administrative challenges of taking up membership, and payment costs. Barriers to enrolment include insufficient information, unaffordability of payments and perceived administrative complexity. Achieving universal coverage requires good physical access to service providers and appropriate benefit options within pre-payment health financing mechanisms.

Moving towards universal coverage in South Africa? Lessons from a voluntary government insurance scheme

PubMed Central

Govender, Veloshnee; Chersich, Matthew F.; Harris, Bronwyn; Alaba, Olufunke; Ataguba, John E.; Nxumalo, Nonhlanhla; Goudge, Jane

2013-01-01

Background In 2005, the South African government introduced a voluntary, subsidised health insurance scheme for civil servants. In light of the global emphasis on universal coverage, empirical evidence is needed to understand the relationship between new health financing strategies and health care access thereby improving global understanding of these issues. Objectives This study analysed coverage of the South African government health insurance scheme, the population groups with low uptake, and the individual-level factors, as well as characteristics of the scheme, that influenced enrolment. Methods Multi-stage random sampling was used to select 1,329 civil servants from the health and education sectors in four of South Africa's nine provinces. They were interviewed to determine factors associated with enrolment in the scheme. The analysis included both descriptive statistics and multivariate logistic regression. Results Notwithstanding the availability of a non-contributory option within the insurance scheme and access to privately-provided primary care, a considerable portion of socio-economically vulnerable groups remained uninsured (57.7% of the lowest salary category). Non-insurance was highest among men, black African or coloured ethnic groups, less educated and lower-income employees, and those living in informal-housing. The relatively poor uptake of the contributory and non-contributory insurance options was mostly attributed to insufficient information, perceived administrative challenges of taking up membership, and payment costs. Conclusion Barriers to enrolment include insufficient information, unaffordability of payments and perceived administrative complexity. Achieving universal coverage requires good physical access to service providers and appropriate benefit options within pre-payment health financing mechanisms. PMID:23364093

Measuring coverage in MNCH: total survey error and the interpretation of intervention coverage estimates from household surveys.

PubMed

Eisele, Thomas P; Rhoda, Dale A; Cutts, Felicity T; Keating, Joseph; Ren, Ruilin; Barros, Aluisio J D; Arnold, Fred

2013-01-01

Nationally representative household surveys are increasingly relied upon to measure maternal, newborn, and child health (MNCH) intervention coverage at the population level in low- and middle-income countries. Surveys are the best tool we have for this purpose and are central to national and global decision making. However, all survey point estimates have a certain level of error (total survey error) comprising sampling and non-sampling error, both of which must be considered when interpreting survey results for decision making. In this review, we discuss the importance of considering these errors when interpreting MNCH intervention coverage estimates derived from household surveys, using relevant examples from national surveys to provide context. Sampling error is usually thought of as the precision of a point estimate and is represented by 95% confidence intervals, which are measurable. Confidence intervals can inform judgments about whether estimated parameters are likely to be different from the real value of a parameter. We recommend, therefore, that confidence intervals for key coverage indicators should always be provided in survey reports. By contrast, the direction and magnitude of non-sampling error is almost always unmeasurable, and therefore unknown. Information error and bias are the most common sources of non-sampling error in household survey estimates and we recommend that they should always be carefully considered when interpreting MNCH intervention coverage based on survey data. Overall, we recommend that future research on measuring MNCH intervention coverage should focus on refining and improving survey-based coverage estimates to develop a better understanding of how results should be interpreted and used.

Measuring Coverage in MNCH: Total Survey Error and the Interpretation of Intervention Coverage Estimates from Household Surveys

PubMed Central

Eisele, Thomas P.; Rhoda, Dale A.; Cutts, Felicity T.; Keating, Joseph; Ren, Ruilin; Barros, Aluisio J. D.; Arnold, Fred

2013-01-01

Nationally representative household surveys are increasingly relied upon to measure maternal, newborn, and child health (MNCH) intervention coverage at the population level in low- and middle-income countries. Surveys are the best tool we have for this purpose and are central to national and global decision making. However, all survey point estimates have a certain level of error (total survey error) comprising sampling and non-sampling error, both of which must be considered when interpreting survey results for decision making. In this review, we discuss the importance of considering these errors when interpreting MNCH intervention coverage estimates derived from household surveys, using relevant examples from national surveys to provide context. Sampling error is usually thought of as the precision of a point estimate and is represented by 95% confidence intervals, which are measurable. Confidence intervals can inform judgments about whether estimated parameters are likely to be different from the real value of a parameter. We recommend, therefore, that confidence intervals for key coverage indicators should always be provided in survey reports. By contrast, the direction and magnitude of non-sampling error is almost always unmeasurable, and therefore unknown. Information error and bias are the most common sources of non-sampling error in household survey estimates and we recommend that they should always be carefully considered when interpreting MNCH intervention coverage based on survey data. Overall, we recommend that future research on measuring MNCH intervention coverage should focus on refining and improving survey-based coverage estimates to develop a better understanding of how results should be interpreted and used. PMID:23667331

Multifaceted diversity-area relationships reveal global hotspots of mammalian species, trait and lineage diversity.

PubMed

Mazel, Florent; Guilhaumon, François; Mouquet, Nicolas; Devictor, Vincent; Gravel, Dominique; Renaud, Julien; Cianciaruso, Marcus Vinicius; Loyola, Rafael Dias; Diniz-Filho, José Alexandre Felizola; Mouillot, David; Thuiller, Wilfried

2014-08-01

To define biome-scale hotspots of phylogenetic and functional mammalian biodiversity (PD and FD, respectively) and compare them to 'classical' hotspots based on species richness (SR) only. Global. SR, PD & FD were computed for 782 terrestrial ecoregions using distribution ranges of 4616 mammalian species. We used a set of comprehensive diversity indices unified by a recent framework that incorporates the species relative coverage in each ecoregion. We build large-scale multifaceted diversity-area relationships to rank ecoregions according to their levels of biodiversity while accounting for the effect of area on each diversity facet. Finally we defined hotspots as the top-ranked ecoregions. While ignoring species relative coverage led to a relative good congruence between biome top ranked SR, PD and FD hotspots, ecoregions harboring a rich and abundantly represented evolutionary history and functional diversity did not match with top ranked ecoregions defined by species richness. More importantly PD and FD hotspots showed important spatial mismatches. We also found that FD and PD generally reached their maximum values faster than species richness as a function of area. The fact that PD/FD reach faster their maximal value than SR may suggest that the two former facets might be less vulnerable to habitat loss than the latter. While this point is expected, it is the first time that it is quantified at global scale and should have important consequences in conservation. Incorporating species relative coverage into the delineation of multifaceted hotspots of diversity lead to weak congruence between SR, PD and FD hotspots. This means that maximizing species number may fail at preserving those nodes (in the phylogenetic or functional tree) that are relatively abundant in the ecoregion. As a consequence it may be of prime importance to adopt a multifaceted biodiversity perspective to inform conservation strategies at global scale.

Multifaceted diversity-area relationships reveal global hotspots of mammalian species, trait and lineage diversity

PubMed Central

Mazel, Florent; Guilhaumon, François; Mouquet, Nicolas; Devictor, Vincent; Gravel, Dominique; Renaud, Julien; Cianciaruso, Marcus Vinicius; Loyola, Rafael Dias; Diniz-Filho, José Alexandre Felizola; Mouillot, David; Thuiller, Wilfried

2014-01-01

Aim To define biome-scale hotspots of phylogenetic and functional mammalian biodiversity (PD and FD, respectively) and compare them to ‘classical’ hotspots based on species richness (SR) only. Location Global Methods SR, PD & FD were computed for 782 terrestrial ecoregions using distribution ranges of 4616 mammalian species. We used a set of comprehensive diversity indices unified by a recent framework that incorporates the species relative coverage in each ecoregion. We build large-scale multifaceted diversity-area relationships to rank ecoregions according to their levels of biodiversity while accounting for the effect of area on each diversity facet. Finally we defined hotspots as the top-ranked ecoregions. Results While ignoring species relative coverage led to a relative good congruence between biome top ranked SR, PD and FD hotspots, ecoregions harboring a rich and abundantly represented evolutionary history and functional diversity did not match with top ranked ecoregions defined by species richness. More importantly PD and FD hotspots showed important spatial mismatches. We also found that FD and PD generally reached their maximum values faster than species richness as a function of area. Main conclusions The fact that PD/FD reach faster their maximal value than SR may suggest that the two former facets might be less vulnerable to habitat loss than the latter. While this point is expected, it is the first time that it is quantified at global scale and should have important consequences in conservation. Incorporating species relative coverage into the delineation of multifaceted hotspots of diversity lead to weak congruence between SR, PD and FD hotspots. This means that maximizing species number may fail at preserving those nodes (in the phylogenetic or functional tree) that are relatively abundant in the ecoregion. As a consequence it may be of prime importance to adopt a multifaceted biodiversity perspective to inform conservation strategies at global scale. PMID:25071413

Evaluating the responses of forest ecosystems to climate change and CO2 using dynamic global vegetation models.

PubMed

Song, Xiang; Zeng, Xiaodong

2017-02-01

The climate has important influences on the distribution and structure of forest ecosystems, which may lead to vital feedback to climate change. However, much of the existing work focuses on the changes in carbon fluxes or water cycles due to climate change and/or atmospheric CO 2 , and few studies have considered how and to what extent climate change and CO 2 influence the ecosystem structure (e.g., fractional coverage change) and the changes in the responses of ecosystems with different characteristics. In this work, two dynamic global vegetation models (DGVMs): IAP-DGVM coupled with CLM3 and CLM4-CNDV, were used to investigate the response of the forest ecosystem structure to changes in climate (temperature and precipitation) and CO 2 concentration. In the temperature sensitivity tests, warming reduced the global area-averaged ecosystem gross primary production in the two models, which decreased global forest area. Furthermore, the changes in tree fractional coverage (Δ F tree ; %) from the two models were sensitive to the regional temperature and ecosystem structure, i.e., the mean annual temperature (MAT; °C) largely determined whether Δ F tree was positive or negative, while the tree fractional coverage ( F tree ; %) played a decisive role in the amplitude of Δ F tree around the globe, and the dependence was more remarkable in IAP-DGVM. In cases with precipitation change, F tree had a uniformly positive relationship with precipitation, especially in the transition zones of forests (30% <  F tree  < 60%) for IAP-DGVM and in semiarid and arid regions for CLM4-CNDV. Moreover, Δ F tree had a stronger dependence on F tree than on the mean annual precipitation (MAP; mm/year). It was also demonstrated that both models captured the fertilization effects of the CO 2 concentration.

Progress Toward Regional Measles Elimination - Worldwide, 2000-2016.

PubMed

Dabbagh, Alya; Patel, Minal K; Dumolard, Laure; Gacic-Dobo, Marta; Mulders, Mick N; Okwo-Bele, Jean-Marie; Kretsinger, Katrina; Papania, Mark J; Rota, Paul A; Goodson, James L

2017-10-27

The fourth United Nations Millennium Development Goal, adopted in 2000, set a target to reduce child mortality by two thirds by 2015. One indicator of progress toward this target was measles vaccination coverage (1). In 2010, the World Health Assembly (WHA) set three milestones for measles control by 2015: 1) increase routine coverage with the first dose of a measles-containing vaccine (MCV1) among children aged 1 year to ≥90% at the national level and to ≥80% in every district; 2) reduce global annual measles incidence to <5 cases per million population; and 3) reduce global measles mortality by 95% from the 2000 estimate (2).* In 2012, WHA endorsed the Global Vaccine Action Plan, † with the objective of eliminating measles in four World Health Organization (WHO) regions by 2015 and in five regions by 2020. Countries in all six WHO regions have adopted goals for measles elimination by or before 2020. Measles elimination is defined as the absence of endemic measles virus transmission in a region or other defined geographic area for ≥12 months, in the presence of a high quality surveillance system that meets targets of key performance indicators. This report updates a previous report (3) and describes progress toward global measles control milestones and regional measles elimination goals during 2000-2016. During this period, annual reported measles incidence decreased 87%, from 145 to 19 cases per million persons, and annual estimated measles deaths decreased 84%, from 550,100 to 89,780; measles vaccination prevented an estimated 20.4 million deaths. However, the 2015 milestones have not yet been met; only one WHO region has been verified as having eliminated measles. Improved implementation of elimination strategies by countries and their partners is needed, with focus on increasing vaccination coverage through substantial and sustained additional investments in health systems, strengthening surveillance systems, using surveillance data to drive programmatic actions, securing political commitment, and raising the visibility of measles elimination goals.

A review of measles supplementary immunization activities and the implications for Pacific Island countries and territories.

PubMed

Clements, C John; Soakai, Taniela Sunia; Sadr-Azodi, Nahad

2017-02-01

Standard measles control strategies include achieving high levels of measles vaccine coverage using routine delivery systems, supplemented by mass immunization campaigns as needed to close population immunity gaps. Areas covered: This review looks at how supplementary immunization activities (SIAs) have contributed to measles control globally, and asks whether such a strategy has a place in Pacific Islands today. Expert commentary: Very high coverage with two doses of measles vaccine seems to be the optimal strategy for controlling measles. By 2015, all but two Pacific Islands had introduced a second dose in the routine schedule; however, a number of countries have not yet reached high coverage with their second dose. The literature and the country reviews reported here suggest that a high coverage SIA combined with one dose of measles vaccine given in the routine system will also do the job. The arguments for and against the use of SIAs are complex, but it is clear that to be effective, SIAs need to be well designed to meet specific needs, must be carried out effectively and safely with very high coverage, and should, when possible, carry with them other public health interventions to make them even more cost-effective.

The climatology of low latitude ionospheric currents derived from CHAMP observations

NASA Astrophysics Data System (ADS)

Stolle, Claudia; Alken, Patrik

2010-05-01

The multi-year data base of magnetic field and ionospheric measurements from the CHAMP satellite contain enormous potential to investigate the behaviour and the origin of currents in the E and F region ionosphere. Special advantage is drawn from the satellite's near polar orbit and the full data coverage over all longitudes and local times. This paper will present findings about two prominent features of the low latitude ionosphere: equatorial plasma irregularities and the equatorial electrojet (EEJ). Equatorial plasma irregularities (commonly known as "bubbles") severely disturb the post sunset F region ionosphere and cause the strongest radio wave scintillations globally during solar maximum years. Using CHAMP vector magnetic field data, it was possible for the first time to show on a long term basis that equatorial plasma irregularities have signatures in all components of the magnetic field. The first ever global climatology of the occurrence rate of these magnetic signatures has been compiled. Such a data base of disturbed orbits is especially useful for core and crustal magnetic field modellers. The magnetic field observations of CHAMP, Ørsted, and SAC-C were employed to develop a climatological model of the EEJ. Measurements of the EEJ and empirical values from electron density and thermospheric density and winds have in addition enabled the development of a climatological model of the equatorial electric field. These results provide excellent opportunity to investigate the seasonal/longitudinal characteristics of the EEJ and the influence of atmospheric waves on E region dynamics.

Remote Sensing of Cloud, Aerosol, and Land Properties from MODIS: Applications to the East Asia Region

NASA Technical Reports Server (NTRS)

King, Michael D.; Platnick, Steven; Moody, Eric G.

2002-01-01

MODIS is an earth-viewing cross-track scanning spectroradiometer launched on the Terra satellite in December 1999 and the Aqua satellite in May 2002. MODIS scans a swath width sufficient to provide nearly complete global coverage every two days from a polar-orbiting, sun-synchronous, platform at an altitude of 705 km, and provides images in 36 spectral bands between 0.415 and 14.235 microns with spatial resolutions of 250 m (2 bands), 500 m (5 bands) and 1000 m (29 bands). These bands have been carefully selected to enable advanced studies of land, ocean, and atmospheric processes. In this paper we will describe the various methods being used for the remote sensing of cloud, aerosol, and surface properties using MODIS data, focusing primarily on (i) the MODIS cloud mask used to distinguish clouds, clear sky, heavy aerosol, and shadows on the ground, (ii) cloud optical properties, especially cloud optical thickness and effective radius of water drops and ice crystals, (iii) aerosol optical thickness and size characteristics both over land and ocean, and (iv) ecosystem classification and surface spectral reflectance. The physical principles behind the determination of each of these products will be described, together with an example of their application using MODIS observations to the east Asian region. All products are archived into two categories: pixel-level retrievals (referred to as Level-2 products) and global gridded products at a latitude and longitude resolution of 1 min (Level-3 products).

The NASA Marshall Space Flight Center Earth Global Reference Atmospheric Model-2010 Version

NASA Technical Reports Server (NTRS)

Leslie, F. W.; Justus, C. G.

2011-01-01

Reference or standard atmospheric models have long been used for design and mission planning of various aerospace systems. The NASA Marshall Space Flight Center Global Reference Atmospheric Model was developed in response to the need for a design reference atmosphere that provides complete global geographical variability and complete altitude coverage (surface to orbital altitudes), as well as complete seasonal and monthly variability of the thermodynamic variables and wind components. In addition to providing the geographical, height, and monthly variation of the mean atmospheric state, it includes the ability to simulate spatial and temporal perturbations.

GPS Eye-in-the-Sky Software Takes Closer Look Below

NASA Technical Reports Server (NTRS)

2006-01-01

At NASA, GPS is a vital resource for scientific research aimed at understanding and protecting Earth. The Agency employs the band of GPS satellites for such functions as mapping Earth s ionosphere and developing earthquake-prediction tools. Extending this worldly wisdom beyond Earth, NASA researchers are even discussing the possibility of developing global positioning satellites around Mars, in anticipation of future manned missions. Despite all of its terrestrial accomplishments, traditional GPS still has its limitations. The Space Agency is working to address these with many new advances, including a "Global Differential GPS" technology that instantaneously provides a position to within 4 inches horizontally and 8 inches vertically, anywhere on Earth. According to NASA's Jet Propulsion Laboratory, no other related system provides the same combination of accuracy and coverage. Furthermore, traditional GPS cannot communicate beyond latitudes of 75deg. That means that most of Greenland and Antarctica cannot receive GPS signals. The Global Differential GPS technology approaches this area of the world using several different GPS signals. These signals overlap to compensate for the gaps in coverage. Now, scientists working in the extreme northernmost and southernmost areas of the world can have access to the same GPS technology that other scientists around the world rely on.

Azimuthally Anisotropic Global Adjoint Tomography

NASA Astrophysics Data System (ADS)

Bozdag, E.; Orsvuran, R.; Lefebvre, M. P.; Lei, W.; Peter, D. B.; Ruan, Y.; Smith, J. A.; Komatitsch, D.; Tromp, J.

2017-12-01

Earth's upper mantle shows significant evidence of anisotropy as a result of its composition and deformation. After the first-generation global adjoint tomography model, GLAD-M15 (Bozdag et al. 2016), which has transverse isotropy confined to upper mantle, we continue our iterations including surface-wave azimuthal anisotropy with an emphasis on the upper mantle. We are focusing on four elastic parameters that surface waves are known to be most sensitive to, namely, vertically and horizontally polarized shear waves and the density-normalised anisotropic parameters Gc' & Gs'. As part of the current anisotropic inversions, which will lead to our "second-generation" global adjoint tomography model, we have started exploring new misfits based on a double-difference approach (Yuan et al. 2016). We define our misfit function in terms of double-difference multitaper measurements, where each waveform is normalized by its number of pairs in the period ranges 45-100 s & 90-250 s. New measurements result in better balanced gradients while extracting more information underneath clusters of stations, such as USArray. Our initial results reveals multi-scale anisotorpic signals depending on ray (kernel) coverage close to continental-scale resolution in areas with dense coverage, consistent with previous studies.

Superposed epoch analysis of ion temperatures during CME- and CIR/HSS-driven storms

NASA Astrophysics Data System (ADS)

Keesee, A. M.; Scime, E. E.

2012-12-01

The NASA Two Wide-angle Imaging Neutral atom Spectrometers (TWINS) Mission provides a global view of the magnetosphere with near-continuous coverage. Utilizing a novel technique to calculate ion temperatures from the TWINS energetic neutral atom (ENA) measurements, we generate ion temperature maps of the magnetosphere. These maps can be used to study ion temperature evolution during geomagnetic storms. A superposed epoch analysis of the ion temperature evolution during 48 storms will be presented. Zaniewski et al. [2006] performed a superposed epoch analysis of ion temperatures by storm interval using data from the MENA instrument on the IMAGE mission, demonstrating significant dayside ion heating during the main phase. The TWINS measurements provide more continuous coverage and improved spatial and temporal resolution. Denton and Borovsky [2008] noted differences in ion temperature evolution at geosynchronous orbit between coronal mass ejection (CME)- and corotating interaction region (CIR)/high speed stream (HSS)- driven storms. Using our global ion temperature maps, we have found consistent results for select individual storms [Keesee et al., 2012]. We will present superposed epoch analyses for the subgroups of CME- and CIR/HSS-driven storms to compare global ion temperature evolution during the two types of storms.

Anatomic tibial component design can increase tibial coverage and rotational alignment accuracy: a comparison of six contemporary designs.

PubMed

Dai, Yifei; Scuderi, Giles R; Bischoff, Jeffrey E; Bertin, Kim; Tarabichi, Samih; Rajgopal, Ashok

2014-12-01

The aim of this study was to comprehensively evaluate contemporary tibial component designs against global tibial anatomy. We hypothesized that anatomically designed tibial components offer increased morphological fit to the resected proximal tibia with increased alignment accuracy compared to symmetric and asymmetric designs. Using a multi-ethnic bone dataset, six contemporary tibial component designs were investigated, including anatomic, asymmetric, and symmetric design types. Investigations included (1) measurement of component conformity to the resected tibia using a comprehensive set of size and shape metrics; (2) assessment of component coverage on the resected tibia while ensuring clinically acceptable levels of rotation and overhang; and (3) evaluation of the incidence and severity of component downsizing due to adherence to rotational alignment and overhang requirements, and the associated compromise in tibial coverage. Differences in coverage were statistically compared across designs and ethnicities, as well as between placements with or without enforcement of proper rotational alignment. Compared to non-anatomic designs investigated, the anatomic design exhibited better conformity to resected tibial morphology in size and shape, higher tibial coverage (92% compared to 85-87%), more cortical support (posteromedial region), lower incidence of downsizing (3% compared to 39-60%), and less compromise of tibial coverage (0.5% compared to 4-6%) when enforcing proper rotational alignment. The anatomic design demonstrated meaningful increase in tibial coverage with accurate rotational alignment compared to symmetric and asymmetric designs, suggesting its potential for less intra-operative compromises and improved performance. III.

Global tracking and inventory of military hardware via LEO satellite: A system approach and likely scenario

NASA Technical Reports Server (NTRS)

Bell, David; Estabrook, Polly; Romer, Richard

1995-01-01

A system for global inventory control of electronically tagged military hardware is achievable using a LEO satellite constellation. An equipment Tag can communicate directly to the satellite with a power of 5 watts or less at a data rate of 2400 to 50,000 bps. As examples, two proposed commercial LEO systems, IRIDIUM and ORBCOMM, are both capable of providing global coverage but with dramatically different telecom capacities. Investigation of these two LEO systems as applied to the Tag scenario provides insight into satellite design trade-offs, constellation trade-offs and signal dynamics that effect the performance of a satellite-based global inventory control system.

Performance of the Falling Snow Retrieval Algorithms for the Global Precipitation Measurement (GPM) Mission

NASA Technical Reports Server (NTRS)

Skofronick-Jackson, Gail; Munchak, Stephen J.; Ringerud, Sarah

2016-01-01

Retrievals of falling snow from space represent an important data set for understanding the Earth's atmospheric, hydrological, and energy cycles, especially during climate change. Estimates of falling snow must be captured to obtain the true global precipitation water cycle, snowfall accumulations are required for hydrological studies, and without knowledge of the frozen particles in clouds one cannot adequately understand the energy and radiation budgets. While satellite-based remote sensing provides global coverage of falling snow events, the science is relatively new and retrievals are still undergoing development with challenges remaining). This work reports on the development and testing of retrieval algorithms for the Global Precipitation Measurement (GPM) mission Core Satellite, launched February 2014.

Intrapartum Antibiotic Chemoprophylaxis Policies for the Prevention of Group B Streptococcal Disease Worldwide: Systematic Review.

PubMed

Le Doare, Kirsty; O'Driscoll, Megan; Turner, Kim; Seedat, Farah; Russell, Neal J; Seale, Anna C; Heath, Paul T; Lawn, Joy E; Baker, Carol J; Bartlett, Linda; Cutland, Clare; Gravett, Michael G; Ip, Margaret; Madhi, Shabir A; Rubens, Craig E; Saha, Samir K; Schrag, Stephanie; Sobanjo-Ter Meulen, Ajoke; Vekemans, Johan; Kampmann, Beate

2017-11-06

Intrapartum antibiotic chemoprophylaxis (IAP) prevents most early-onset group B streptococcal (GBS) disease. However, there is no description of how IAP is used around the world. This article is the sixth in a series estimating the burden of GBS disease. Here we aimed to review GBS screening policies and IAP implementation worldwide. We identified data through (1) systematic literature reviews (PubMed/Medline, Embase, Literature in the Health Sciences in Latin America and the Caribbean [LILACS], World Health Organization library database [WHOLIS], and Scopus) and unpublished data from professional societies and (2) an online survey and searches of policies from medical societies and professionals. We included data on whether an IAP policy was in use, and if so whether it was based on microbiological or clinical risk factors and how these were applied, as well as the estimated coverage (percentage of women receiving IAP where indicated). We received policy information from 95 of 195 (49%) countries. Of these, 60 of 95 (63%) had an IAP policy; 35 of 60 (58%) used microbiological screening, 25 of 60 (42%) used clinical risk factors. Two of 15 (13%) low-income, 4 of 16 (25%) lower-middle-income, 14 of 20 (70%) upper-middle-income, and 40 of 44 (91%) high-income countries had any IAP policy. The remaining 35 of 95 (37%) had no national policy (25/33 from low-income and lower-middle-income countries). Coverage varied considerably; for microbiological screening, median coverage was 80% (range, 20%-95%); for clinical risk factor-based screening, coverage was 29% (range, 10%-50%). Although there were differences in the microbiological screening methods employed, the individual clinical risk factors used were similar. There is considerable heterogeneity in IAP screening policies and coverage worldwide. Alternative global strategies, such as maternal vaccination, are needed to enhance the scope of global prevention of GBS disease. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.

A Multi-scale Modeling System: Developments, Applications and Critical Issues

NASA Technical Reports Server (NTRS)

Tao, Wei-Kuo; Chern, Jiundar; Atlas, Robert; Randall, David; Lin, Xin; Khairoutdinov, Marat; Li, Jui-Lin; Waliser, Duane E.; Hou, Arthur; Peters-Lidard, Christa;

Governing for the Common Good.

PubMed

Ruger, Jennifer Prah

2015-12-01

The proper object of global health governance (GHG) should be the common good, ensuring that all people have the opportunity to flourish. A well-organized global society that promotes the common good is to everyone's advantage. Enabling people to flourish includes enabling their ability to be healthy. Thus, we must assess health governance by its effectiveness in enhancing health capabilities. Current GHG fails to support human flourishing, diminishes health capabilities and thus does not serve the common good. The provincial globalism theory of health governance proposes a Global Health Constitution and an accompanying Global Institute of Health and Medicine that together propose to transform health governance. Multiple lines of empirical research suggest that these institutions would be effective, offering the most promising path to a healthier, more just world.

Space technology and the optical sciences.

PubMed

Yates, H W

1982-01-15

The earth-orbiting satellites and the deep-space probes have provided for the optical sciences platforms from which to study the earth, the solar system, and the universe with truly revolutionary capability. For the terrestrial sciences the orbiting platforms for optical measurements in both low and geostationary orbits have given us a view of our planet and a global coverage never before possible. For the astronomical applications of optical instruments that "cataract of the telescopic eye," the atmosphere of the earth has been left behind and through proximity, including actual contact, we now have resolution and spectral coverage limited only by money and motive.

Usability and Interoperability Improvements for an EASE-Grid 2.0 Passive Microwave Data Product Using CF Conventions

NASA Astrophysics Data System (ADS)

Hardman, M.; Brodzik, M. J.; Long, D. G.

2017-12-01

Beginning in 1978, the satellite passive microwave data record has been a mainstay of remote sensing of the cryosphere, providing twice-daily, near-global spatial coverage for monitoring changes in hydrologic and cryospheric parameters that include precipitation, soil moisture, surface water, vegetation, snow water equivalent, sea ice concentration and sea ice motion. Historical versions of the gridded passive microwave data sets were produced as flat binary files described in human-readable documentation. This format is error-prone and makes it difficult to reliably include all processing and provenance. Funded by NASA MEaSUREs, we have completely reprocessed the gridded data record that includes SMMR, SSM/I-SSMIS and AMSR-E. The new Calibrated Enhanced-Resolution Brightness Temperature (CETB) Earth System Data Record (ESDR) files are self-describing. Our approach to the new data set was to create netCDF4 files that use standard metadata conventions and best practices to incorporate file-level, machine- and human-readable contents, geolocation, processing and provenance metadata. We followed the flexible and adaptable Climate and Forecast (CF-1.6) Conventions with respect to their coordinate conventions and map projection parameters. Additionally, we made use of Attribute Conventions for Dataset Discovery (ACDD-1.3) that provided file-level conventions with spatio-temporal bounds that enable indexing software to search for coverage. Our CETB files also include temporal coverage and spatial resolution in the file-level metadata for human-readability. We made use of the JPL CF/ACDD Compliance Checker to guide this work. We tested our file format with real software, for example, netCDF Command-line Operators (NCO) power tools for unlimited control on spatio-temporal subsetting and concatenation of files. The GDAL tools understand the CF metadata and produce fully-compliant geotiff files from our data. ArcMap can then reproject the geotiff files on-the-fly and work with other geolocated data such as coastlines, with no special work required. We expect this combination of standards and well-tested interoperability to significantly improve the usability of this important ESDR for the Earth Science community.

Possible Courses for News and Public Affairs

ERIC Educational Resources Information Center

Wald, Richard C.

1978-01-01

Live programming, regular daily news programs, and documentary series, which are suggested as solutions to the limited scope of news and public affairs air time, would enable PBS to increase its coverage of news and public affairs. Some suggestions are also made for restructuring the functions of stations within the system to facilitate this…

Guidelines for whole genome bisulphite sequencing of intact and FFPET DNA on the Illumina HiSeq X Ten.

PubMed

Nair, Shalima S; Luu, Phuc-Loi; Qu, Wenjia; Maddugoda, Madhavi; Huschtscha, Lily; Reddel, Roger; Chenevix-Trench, Georgia; Toso, Martina; Kench, James G; Horvath, Lisa G; Hayes, Vanessa M; Stricker, Phillip D; Hughes, Timothy P; White, Deborah L; Rasko, John E J; Wong, Justin J-L; Clark, Susan J

2018-05-28

Comprehensive genome-wide DNA methylation profiling is critical to gain insights into epigenetic reprogramming during development and disease processes. Among the different genome-wide DNA methylation technologies, whole genome bisulphite sequencing (WGBS) is considered the gold standard for assaying genome-wide DNA methylation at single base resolution. However, the high sequencing cost to achieve the optimal depth of coverage limits its application in both basic and clinical research. To achieve 15× coverage of the human methylome, using WGBS, requires approximately three lanes of 100-bp-paired-end Illumina HiSeq 2500 sequencing. It is important, therefore, for advances in sequencing technologies to be developed to enable cost-effective high-coverage sequencing. In this study, we provide an optimised WGBS methodology, from library preparation to sequencing and data processing, to enable 16-20× genome-wide coverage per single lane of HiSeq X Ten, HCS 3.3.76. To process and analyse the data, we developed a WGBS pipeline (METH10X) that is fast and can call SNPs. We performed WGBS on both high-quality intact DNA and degraded DNA from formalin-fixed paraffin-embedded tissue. First, we compared different library preparation methods on the HiSeq 2500 platform to identify the best method for sequencing on the HiSeq X Ten. Second, we optimised the PhiX and genome spike-ins to achieve higher quality and coverage of WGBS data on the HiSeq X Ten. Third, we performed integrated whole genome sequencing (WGS) and WGBS of the same DNA sample in a single lane of HiSeq X Ten to improve data output. Finally, we compared methylation data from the HiSeq 2500 and HiSeq X Ten and found high concordance (Pearson r > 0.9×). Together we provide a systematic, efficient and complete approach to perform and analyse WGBS on the HiSeq X Ten. Our protocol allows for large-scale WGBS studies at reasonable processing time and cost on the HiSeq X Ten platform.

SDN-enabled hybrid emergency message transmission architecture in internet-of-vehicles

NASA Astrophysics Data System (ADS)

Zhu, Wanting; Gao, Deyun; Zhao, Weicheng; Zhang, Hongke; Chiang, Hua-Pei

2018-04-01

With the increasing number of vehicles connected to the Internet-of-Things (IoT), Internet-of-Vehicles (IoV) is becoming a hot research topic. It can improve traffic safety and efficiency and promote the development of the intelligent transportation that is a very important element in Smart Cities. As an important part of the safety application in IoV, the emergency message transmission is designed to inform all the vehicles in the relevant area timely of the accident information through the multi-hop broadcast communication. In this paper, we propose a hybrid emergency message transmission (HEMT), which introduces the SDN technology into the vehicular network environment and utilizes the flexibility of inter-vehicle communication. By deploying SDN-enabled central controller and RSU switches, we can obtain reliable and fast emergency message dissemination. Moreover, considering the space between the coverages of RSUs caused by the sparse deployment, we also use inter-vehicle multi-hop broadcast communication to improve the message coverage ratio by adding the packet modification module on the RSU switch. Simulation results show the feasibility and effectiveness of our proposed scheme.

Quantitative proteomics in cardiovascular research: global and targeted strategies

PubMed Central

Shen, Xiaomeng; Young, Rebeccah; Canty, John M.; Qu, Jun

2014-01-01

Extensive technical advances in the past decade have substantially expanded quantitative proteomics in cardiovascular research. This has great promise for elucidating the mechanisms of cardiovascular diseases (CVD) and the discovery of cardiac biomarkers used for diagnosis and treatment evaluation. Global and targeted proteomics are the two major avenues of quantitative proteomics. While global approaches enable unbiased discovery of altered proteins via relative quantification at the proteome level, targeted techniques provide higher sensitivity and accuracy, and are capable of multiplexed absolute quantification in numerous clinical/biological samples. While promising, technical challenges need to be overcome to enable full utilization of these techniques in cardiovascular medicine. Here we discuss recent advances in quantitative proteomics and summarize applications in cardiovascular research with an emphasis on biomarker discovery and elucidating molecular mechanisms of disease. We propose the integration of global and targeted strategies as a high-throughput pipeline for cardiovascular proteomics. Targeted approaches enable rapid, extensive validation of biomarker candidates discovered by global proteomics. These approaches provide a promising alternative to immunoassays and other low-throughput means currently used for limited validation. PMID:24920501

The New Global Health

PubMed Central

Simone, Patricia M.; Davison, Veronica; Slutsker, Laurence

2013-01-01

Global health reflects the realities of globalization, including worldwide dissemination of infectious and noninfectious public health risks. Global health architecture is complex and better coordination is needed between multiple organizations. Three overlapping themes determine global health action and prioritization: development, security, and public health. These themes play out against a background of demographic change, socioeconomic development, and urbanization. Infectious diseases remain critical factors, but are no longer the major cause of global illness and death. Traditional indicators of public health, such as maternal and infant mortality rates no longer describe the health status of whole societies; this change highlights the need for investment in vital registration and disease-specific reporting. Noncommunicable diseases, injuries, and mental health will require greater attention from the world in the future. The new global health requires broader engagement by health organizations and all countries for the objectives of health equity, access, and coverage as priorities beyond the Millennium Development Goals are set. PMID:23876365

The NASA MSFC Earth Global Reference Atmospheric Model-2007 Version

NASA Technical Reports Server (NTRS)

Leslie, F.W.; Justus, C.G.

2008-01-01

Reference or standard atmospheric models have long been used for design and mission planning of various aerospace systems. The NASA/Marshall Space Flight Center (MSFC) Global Reference Atmospheric Model (GRAM) was developed in response to the need for a design reference atmosphere that provides complete global geographical variability, and complete altitude coverage (surface to orbital altitudes) as well as complete seasonal and monthly variability of the thermodynamic variables and wind components. A unique feature of GRAM is that, addition to providing the geographical, height, and monthly variation of the mean atmospheric state, it includes the ability to simulate spatial and temporal perturbations in these atmospheric parameters (e.g. fluctuations due to turbulence and other atmospheric perturbation phenomena). A summary comparing GRAM features to characteristics and features of other reference or standard atmospheric models, can be found Guide to Reference and Standard Atmosphere Models. The original GRAM has undergone a series of improvements over the years with recent additions and changes. The software program is called Earth-GRAM2007 to distinguish it from similar programs for other bodies (e.g. Mars, Venus, Neptune, and Titan). However, in order to make this Technical Memorandum (TM) more readable, the software will be referred to simply as GRAM07 or GRAM unless additional clarity is needed. Section 1 provides an overview of the basic features of GRAM07 including the newly added features. Section 2 provides a more detailed description of GRAM07 and how the model output generated. Section 3 presents sample results. Appendices A and B describe the Global Upper Air Climatic Atlas (GUACA) data and the Global Gridded Air Statistics (GGUAS) database. Appendix C provides instructions for compiling and running GRAM07. Appendix D gives a description of the required NAMELIST format input. Appendix E gives sample output. Appendix F provides a list of available parameters to enable the user to generate special output. Appendix G gives an example and guidance on incorporating GRAM07 as a subroutine in other programs such as trajectory codes or orbital propagation routines.

Global Adjoint Tomography: Combining Big Data with HPC Simulations

NASA Astrophysics Data System (ADS)

Bozdag, E.; Lefebvre, M. P.; Lei, W.; Peter, D. B.; Smith, J. A.; Komatitsch, D.; Tromp, J.

2014-12-01

The steady increase in data quality and the number of global seismographic stations have substantially grown the amount of data available for construction of Earth models. Meanwhile, developments in the theory of wave propagation, numerical methods and HPC systems have enabled unprecedented simulations of seismic wave propagation in realistic 3D Earth models which lead the extraction of more information from data, ultimately culminating in the use of entire three-component seismograms.Our aim is to take adjoint tomography further to image the entire planet which is one of the extreme cases in seismology due to its intense computational requirements and vast amount of high-quality seismic data that can potentially be assimilated in inversions. We have started low resolution (T > 27 s, soon will be > 17 s) global inversions with 253 earthquakes for a transversely isotropic crust and mantle model on Oak Ridge National Laboratory's Cray XK7 "Titan" system. Recent improvements in our 3D solvers, such as the GPU version of the SPECFEM3D_GLOBE package, will allow us perform higher-resolution (T > 9 s) and longer-duration (~180 m) simulations to take the advantage of high-frequency body waves and major-arc surface waves to improve imbalanced ray coverage as a result of uneven distribution of sources and receivers on the globe. Our initial results after 10 iterations already indicate several prominent features reported in high-resolution continental studies, such as major slabs (Hellenic, Japan, Bismarck, Sandwich, etc.) and enhancement in plume structures (the Pacific superplume, the Hawaii hot spot, etc.). Our ultimate goal is to assimilate seismic data from more than 6,000 earthquakes within the magnitude range 5.5 ≤ Mw ≤ 7.0. To take full advantage of this data set on ORNL's computational resources, we need a solid framework for managing big data sets during pre-processing (e.g., data requests and quality checks), gradient calculations, and post-processing (e.g., pre-conditioning and smoothing gradients) where we address the bottlenecks in our global seismic workflow based on ORNL's ADIOS libraries. We will present our "first generation" model, discuss challenges and future directions in global seismology.

Towards SWOT data assimilation for hydrology : automatic calibration of global flow routing model parameters in the Amazon basin

NASA Astrophysics Data System (ADS)

Mouffe, M.; Getirana, A.; Ricci, S. M.; Lion, C.; Biancamaria, S.; Boone, A.; Mognard, N. M.; Rogel, P.

2011-12-01

The Surface Water and Ocean Topography (SWOT) mission is a swath mapping radar interferometer that will provide global measurements of water surface elevation (WSE). The revisit time depends upon latitude and varies from two (low latitudes) to ten (high latitudes) per 22-day orbit repeat period. The high resolution and the global coverage of the SWOT data open the way for new hydrology studies. Here, the aim is to investigate the use of virtually generated SWOT data to improve discharge simulation using data assimilation techniques. In the framework of the SWOT virtual mission (VM), this study presents the first results of the automatic calibration of a global flow routing (GFR) scheme using SWOT VM measurements for the Amazon basin. The Hydrological Modeling and Analysis Platform (HyMAP) is used along with the MOCOM-UA multi-criteria global optimization algorithm. HyMAP has a 0.25-degree spatial resolution and runs at the daily time step to simulate discharge, water levels and floodplains. The surface runoff and baseflow drainage derived from the Interactions Sol-Biosphère-Atmosphère (ISBA) model are used as inputs for HyMAP. Previous works showed that the use of ENVISAT data enables the reduction of the uncertainty on some of the hydrological model parameters, such as river width and depth, Manning roughness coefficient and groundwater time delay. In the framework of the SWOT preparation work, the automatic calibration procedure was applied using SWOT VM measurements. For this Observing System Experiment (OSE), the synthetical data were obtained applying an instrument simulator (representing realistic SWOT errors) for one hydrological year to HYMAP simulated WSE using a "true" set of parameters. Only pixels representing rivers larger than 100 meters within the Amazon basin are considered to produce SWOT VM measurements. The automatic calibration procedure leads to the estimation of optimal parametersminimizing objective functions that formulate the difference between SWOT observations and modeled WSE using a perturbed set of parameters. Different formulations of the objective function were used, especially to account for SWOT observation errors, as well as various sets of calibration parameters.

Global investment targets for malaria control and elimination between 2016 and 2030

PubMed Central

Patouillard, Edith; Griffin, Jamie; Bhatt, Samir; Ghani, Azra; Cibulskis, Richard

2017-01-01

Background Access to malaria control interventions falls short of universal health coverage. The Global Technical Strategy for malaria targets at least 90% reduction in case incidence and mortality rates, and elimination in 35 countries by 2030. The potential to reach these targets will be determined in part by investments in malaria. This study estimates the financing required for malaria control and elimination over the 2016–2030 period. Methods A mathematical transmission model was used to explore the impact of increasing intervention coverage on burden and costs. The cost analysis took a public provider perspective covering all 97 malaria endemic countries and territories in 2015. All control interventions currently recommended by the WHO were considered. Cost data were sourced from procurement databases, the peer-reviewed literature, national malaria strategic plans, the WHO-CHOICE project and key informant interviews. Results Annual investments of $6.4 billion (95% uncertainty interval (UI $4.5–$9.0 billion)) by 2020, $7.7 billion (95% UI $5.4–$10.9 billion) by 2025 and $8.7 billion (95% UI $6.0–$12.3 billion) by 2030 will be required to reach the targets set in the Global Technical Strategy. These are equivalent to annual investment per person at risk of malaria of US$3.90 by 2020, US$4.30 by 2025 and US$4.40 by 2030, compared with US$2.30 if interventions were sustained at current coverage levels. The 20 countries with the highest burden in 2015 will require 88% of the total investment. Conclusions Given the challenges in increasing domestic and international funding, the efficient use of currently available resources should be a priority. PMID:29242750

Global investment targets for malaria control and elimination between 2016 and 2030.

PubMed

Patouillard, Edith; Griffin, Jamie; Bhatt, Samir; Ghani, Azra; Cibulskis, Richard

2017-01-01

Access to malaria control interventions falls short of universal health coverage. The Global Technical Strategy for malaria targets at least 90% reduction in case incidence and mortality rates, and elimination in 35 countries by 2030. The potential to reach these targets will be determined in part by investments in malaria. This study estimates the financing required for malaria control and elimination over the 2016-2030 period. A mathematical transmission model was used to explore the impact of increasing intervention coverage on burden and costs. The cost analysis took a public provider perspective covering all 97 malaria endemic countries and territories in 2015. All control interventions currently recommended by the WHO were considered. Cost data were sourced from procurement databases, the peer-reviewed literature, national malaria strategic plans, the WHO-CHOICE project and key informant interviews. Annual investments of $6.4 billion (95% uncertainty interval (UI $4.5-$9.0 billion)) by 2020, $7.7 billion (95% UI $5.4-$10.9 billion) by 2025 and $8.7 billion (95% UI $6.0-$12.3 billion) by 2030 will be required to reach the targets set in the Global Technical Strategy. These are equivalent to annual investment per person at risk of malaria of US$3.90 by 2020, US$4.30 by 2025 and US$4.40 by 2030, compared with US$2.30 if interventions were sustained at current coverage levels. The 20 countries with the highest burden in 2015 will require 88% of the total investment. Given the challenges in increasing domestic and international funding, the efficient use of currently available resources should be a priority.

Functional architecture and global properties of the Corynebacterium glutamicum regulatory network: Novel insights from a dataset with a high genomic coverage.

PubMed

Freyre-González, Julio A; Tauch, Andreas

2017-09-10

Corynebacterium glutamicum is a Gram-positive, anaerobic, rod-shaped soil bacterium able to grow on a diversity of carbon sources like sugars and organic acids. It is a biotechnological relevant organism because of its highly efficient ability to biosynthesize amino acids, such as l-glutamic acid and l-lysine. Here, we reconstructed the most complete C. glutamicum regulatory network to date and comprehensively analyzed its global organizational properties, systems-level features and functional architecture. Our analyses show the tremendous power of Abasy Atlas to study the functional organization of regulatory networks. We created two models of the C. glutamicum regulatory network: all-evidences (containing both weak and strong supported interactions, genomic coverage=73%) and strongly-supported (only accounting for strongly supported evidences, genomic coverage=71%). Using state-of-the-art methodologies, we prove that power-law behaviors truly govern the connectivity and clustering coefficient distributions. We found a non-previously reported circuit motif that we named complex feed-forward motif. We highlighted the importance of feedback loops for the functional architecture, beyond whether they are statistically over-represented or not in the network. We show that the previously reported top-down approach is inadequate to infer the hierarchy governing a regulatory network because feedback bridges different hierarchical layers, and the top-down approach disregards the presence of intermodular genes shaping the integration layer. Our findings all together further support a diamond-shaped, three-layered hierarchy exhibiting some feedback between processing and coordination layers, which is shaped by four classes of systems-level elements: global regulators, locally autonomous modules, basal machinery and intermodular genes. Copyright © 2016 Elsevier B.V. All rights reserved.

EVA: Evryscopes for the Arctic and Antarctic

NASA Astrophysics Data System (ADS)

Richichi, A.; Law, N.; Tasuya, O.; Fors, O.; Dennihy, E.; Carlberg, R.; Tuthill, P.; Ashley, M.; Soonthornthum, B.

2017-06-01

We are planning to build Evryscopes for the Arctic and Antarctic (EVA), which will enable the first ultra-wide-field, high-cadence sky survey to be conducted from both Poles. The system is based on the successful Evryscope concept, already installed and operating since 2015 at Cerro Tololo in Chile with the following characteristics: robotic operation, 8,000 square degrees simultaneous sky coverage, 2-minute cadence, milli-mag level photometric accuracy, pipelined data processing for real-time analysis and full data storage for off-line analysis. The initial location proposed for EVA is the PEARL station on Ellesmere island; later also an antarctic location shall be selected. The science goals enabled by this unique combination of almost full-sky coverage and high temporal cadence are numerous, and include among others ground-breaking forays in the fields of exoplanets, stellar variability, asteroseismology, supernovae and other transient events. The EVA polar locations will enable uninterrupted observations lasting in principle over weeks and months. EVA will be fully robotic. We discuss the EVA science drivers and expected results, and present the logistics and the outline of the project which is expected to have first light in the winter of 2018. The cost envelope can be kept very competitive thanks to R&D already employed for the CTIO Evryscope, to our experience with both Arctic and Antarctic locations, and to the use of off-the-shelf components.

Predictors of healthcare utilization among older Mexican Americans.

PubMed

Al Snih, Soham; Markides, Kyriakos S; Ray, Laura A; Freeman, Jean L; Ostir, Glenn V; Goodwin, James S

2006-01-01

To examine the effects of predisposing, enabling, and need factors on physician and hospital use among older Mexican Americans. A two-year prospective cohort study. Five Southwestern states: Texas, New Mexico, Colorado, Arizona, and California. A population-based sample of 1987 non-institutionalized Mexican American men and women age > or =65 years. Physician and hospital utilization. Predictor variables included predisposing, enabling, and need factors. Ordinary least square and logistic regression analysis were used to model the effects of predictor factors specified in the Andersen model of health service use on physician and hospital use. After two years of follow-up, predisposing and enabling factors accounted for <5% of the variance in physician and hospital use. Need factors explained 21% of the variance in physician use and 7% of the variance in hospital use. Older age; being female; insurance coverage; having arthritis, diabetes, heart attack, hypertension, stroke, or cancer; and number of medications were factors associated with higher physician utilization. Subjects with arthritis, diabetes, hip fracture, high depressive symptoms, activities of daily living (ADL) disability, or high number of medications increased the odds of having any hospitalization. Subjects with diabetes, heart attack, hip fracture, ADL disabled, and high number of medications had a greater number of hospital nights than their counterparts. Older age, female sex, insurance coverage, and prevalent medical conditions are determinants of healthcare use among older Mexican Americans.

Oceanic primary production 2. Estimation at global scale from satellite (coastal zone color scanner) chlorophyll

NASA Astrophysics Data System (ADS)

Antoine, David; André, Jean-Michel; Morel, André

A fast method has been proposed [Antoine and Morel, this issue] to compute the oceanic primary production from the upper ocean chlorophyll-like pigment concentration, as it can be routinely detected by a spaceborne ocean color sensor. This method is applied here to the monthly global maps of the photosynthetic pigments that were derived from the coastal zone color scanner (CZCS) data archive [Feldman et al., 1989]. The photosynthetically active radiation (PAR) field is computed from the astronomical constant and by using an atmospheric model, thereafter combined with averaged cloud information, derived from the International Satellite Cloud Climatology Project (ISCCP). The aim is to assess the seasonal evolution, as well as the spatial distribution of the photosynthetic carbon fixation within the world ocean and for a ``climatological year,'' to the extent that both the chlorophyll information and the cloud coverage statistics actually are averages obtained over several years. The computed global annual production actually ranges between 36.5 and 45.6 Gt C yr-1 according to the assumption which is made (0.8 or 1) about the ratio of active-to-total pigments (recall that chlorophyll and pheopigments are not radiometrically resolved by CZCS). The relative contributions to the global productivity of the various oceans and zonal belts are examined. By considering the hypotheses needed in such computations, the nature of the data used as inputs, and the results of the sensitivity studies, the global numbers have to be cautiously considered. Improving the reliability of the primary production estimates implies (1) new global data sets allowing a higher temporal resolution and a better coverage, (2) progress in the knowledge of physiological responses of phytoplankton and therefore refinements of the time and space dependent parameterizations of these responses.

Microwave sensing technology issues related to a global change technology architecture trade study

NASA Technical Reports Server (NTRS)

Campbell, Thomas G.; Shiue, Jim; Connolly, Denis; Woo, Ken

1991-01-01

The objectives are to enable the development of lighter and less power consuming, high resolution microwave sensors which will operate at frequencies from 1 to 200 GHz. These systems will use large aperture antenna systems (both reflector and phased arrays) capable of wide scan angle, high polarization purity, and utilize sidelobe suppression techniques as required. Essentially, the success of this technology program will enable high resolution microwave radiometers from geostationary orbit, lightweight and more efficient radar systems from low Earth orbit, and eliminate mechanical scanning methods to the fullest extent possible; a main source of platform instability in large space systems. The Global Change Technology Initiative (GCTI) will develop technology which will enable the use of satellite systems for Earth observations on a global scale.

Methodology for the assessment of brucellosis management practices and its vaccination campaign: example in two Argentine districts.

PubMed

Aznar, M N; Arregui, M; Humblet, M F; Samartino, L E; Saegerman, C

2017-09-07

In Argentina, vaccination with Brucella abortus Strain 19 vaccine is mandatory. The objective of the study was to develop and test a method for evaluating, in an innovative way, some farmers' and veterinarians' management practices in relation to brucellosis and to assess the vaccination campaign and coverage. The work took place in Brandsen and Navarro districts. Four questionnaires were designed (for officials from Local Sanitary Entities, vaccinators, vet practitioners and farmers). Responses were coded as "ideal" (0) and "not ideal" (1). To assess the relative weight of each question ("item"), experts ranked the items according to their impact on management practices and vaccination. A weighted score was then calculated. A higher weighted score was assigned to the worse practices. Farmers obtaining a global weighted score above the third quartile were classified as "inappropriately managed farms", to be compared per type of production system and district. To assess the immunization coverage, female calves were sampled 30 to 50 days post vaccination; they were expected to react positively to serological diagnostic tests (DT+). There were significantly more inappropriately managed farms and higher global scores among beef farmers and in Brandsen. Eighty three percent (83%) of female calves were DT+, significantly under the ideal immunization coverage (95%). Only 48% of farms were considered well vaccinated. DT+ results were positively associated with the Brandsen district (OR = 25.94 [4.60-1146.21] and with the farms having more than 200 cow heads ((OR = 78.34 [4.09-1500.00]). On the contrary, DT+ were less associated with vaccinators being veterinary practitioners (OR = 0.07 [0.006-0.78]). Farmers are well advised by their veterinary practitioners but they should improve some management practices. The vaccination campaign is globally well implemented, but the immunization coverage and some vaccinators' practices should be improved. This study leads to a better understanding of the most common used management and control practices regarding brucellosis, which affect its epidemiology. Any vaccination campaign should be periodically assessed to highlight possible fails. The described methodology can be extrapolated to other countries and different contexts.

Utilization of cone-beam CT for offline evaluation of target volume coverage during prostate image-guided radiotherapy based on bony anatomy alignment.

PubMed

Paluska, Petr; Hanus, Josef; Sefrova, Jana; Rouskova, Lucie; Grepl, Jakub; Jansa, Jan; Kasaova, Linda; Hodek, Miroslav; Zouhar, Milan; Vosmik, Milan; Petera, Jiri

2012-01-01

To assess target volume coverage during prostate image-guided radiotherapy based on bony anatomy alignment and to assess possibility of safety margin reduction. Implementation of IGRT should influence safety margins. Utilization of cone-beam CT provides current 3D anatomic information directly in irradiation position. Such information enables reconstruction of the actual dose distribution. Seventeen prostate patients were treated with daily bony anatomy image-guidance. Cone-beam CT (CBCT) scans were acquired once a week immediately after bony anatomy alignment. After the prostate, seminal vesicles, rectum and bladder were contoured, the delivered dose distribution was reconstructed. Target dose coverage was evaluated by the proportion of the CTV encompassed by the 95% isodose. Original plans employed a 1 cm safety margin. Alternative plans assuming a smaller 7 mm margin between CTV and PTV were evaluated in the same way. Rectal and bladder volumes were compared with the initial ones. Rectal and bladder volumes irradiated with doses higher than 75 Gy, 70 Gy, 60 Gy, 50 Gy and 40 Gy were analyzed. In 12% of reconstructed plans the prostate coverage was not sufficient. The prostate underdosage was observed in 5 patients. Coverage of seminal vesicles was not satisfactory in 3% of plans. Most of the target underdosage corresponded to excessive rectal or bladder filling. Evaluation of alternative plans assuming a smaller 7 mm margin revealed 22% and 11% of plans where prostate and seminal vesicles coverage, respectively, was compromised. These were distributed over 8 and 7 patients, respectively. Sufficient dose coverage of target volumes was not achieved for all patients. Reducing of safety margin is not acceptable. Initial rectal and bladder volumes cannot be considered representative for subsequent treatment.

A long way to go - Estimates of combined water, sanitation and hygiene coverage for 25 sub-Saharan African countries.

PubMed

Roche, Rachel; Bain, Robert; Cumming, Oliver

2017-01-01

Water, sanitation and hygiene (WASH) are essential for a healthy and dignified life. International targets to reduce inadequate WASH coverage were set under the Millennium Development Goals (MDGs, 1990-2015) and now the Sustainable Development Goals (SDGs, 2016-2030). The MDGs called for halving the proportion of the population without access to adequate water and sanitation, whereas the SDGs call for universal access, require the progressive reduction of inequalities, and include hygiene in addition to water and sanitation. Estimating access to complete WASH coverage provides a baseline for monitoring during the SDG period. Sub-Saharan Africa (SSA) has among the lowest rates of WASH coverage globally. The most recent available Demographic Household Survey (DHS) or Multiple Indicator Cluster Survey (MICS) data for 25 countries in SSA were analysed to estimate national and regional coverage for combined water and sanitation (a combined MDG indicator for 'improved' access) and combined water with collection time within 30 minutes plus sanitation and hygiene (a combined SDG indicator for 'basic' access). Coverage rates were estimated separately for urban and rural populations and for wealth quintiles. Frequency ratios and percentage point differences for urban and rural coverage were calculated to give both relative and absolute measures of urban-rural inequality. Wealth inequalities were assessed by visual examination of coverage across wealth quintiles in urban and rural populations and by calculating concentration indices as standard measures of relative wealth related inequality that give an indication of how unevenly a health indicator is distributed across the wealth distribution. Combined MDG coverage in SSA was 20%, and combined basic SDG coverage was 4%; an estimated 921 million people lacked basic SDG coverage. Relative measures of inequality were higher for combined basic SDG coverage than combined MDG coverage, but absolute inequality was lower. Rural combined basic SDG coverage was close to zero in many countries. Our estimates help to quantify the scale of progress required to achieve universal WASH access in low-income countries, as envisaged under the water and sanitation SDG. Monitoring and reporting changes in the proportion of the national population with access to water, sanitation and hygiene may be useful in focusing WASH policy and investments towards the areas of greatest need.

A long way to go – Estimates of combined water, sanitation and hygiene coverage for 25 sub-Saharan African countries

PubMed Central

Bain, Robert; Cumming, Oliver

2017-01-01

Background Water, sanitation and hygiene (WASH) are essential for a healthy and dignified life. International targets to reduce inadequate WASH coverage were set under the Millennium Development Goals (MDGs, 1990–2015) and now the Sustainable Development Goals (SDGs, 2016–2030). The MDGs called for halving the proportion of the population without access to adequate water and sanitation, whereas the SDGs call for universal access, require the progressive reduction of inequalities, and include hygiene in addition to water and sanitation. Estimating access to complete WASH coverage provides a baseline for monitoring during the SDG period. Sub-Saharan Africa (SSA) has among the lowest rates of WASH coverage globally. Methods The most recent available Demographic Household Survey (DHS) or Multiple Indicator Cluster Survey (MICS) data for 25 countries in SSA were analysed to estimate national and regional coverage for combined water and sanitation (a combined MDG indicator for ‘improved’ access) and combined water with collection time within 30 minutes plus sanitation and hygiene (a combined SDG indicator for ‘basic’ access). Coverage rates were estimated separately for urban and rural populations and for wealth quintiles. Frequency ratios and percentage point differences for urban and rural coverage were calculated to give both relative and absolute measures of urban-rural inequality. Wealth inequalities were assessed by visual examination of coverage across wealth quintiles in urban and rural populations and by calculating concentration indices as standard measures of relative wealth related inequality that give an indication of how unevenly a health indicator is distributed across the wealth distribution. Results Combined MDG coverage in SSA was 20%, and combined basic SDG coverage was 4%; an estimated 921 million people lacked basic SDG coverage. Relative measures of inequality were higher for combined basic SDG coverage than combined MDG coverage, but absolute inequality was lower. Rural combined basic SDG coverage was close to zero in many countries. Conclusions Our estimates help to quantify the scale of progress required to achieve universal WASH access in low-income countries, as envisaged under the water and sanitation SDG. Monitoring and reporting changes in the proportion of the national population with access to water, sanitation and hygiene may be useful in focusing WASH policy and investments towards the areas of greatest need. PMID:28182796

Analysing biodiversity and conservation knowledge products to support regional environmental assessments.

PubMed

Brooks, Thomas M; Akçakaya, H Resit; Burgess, Neil D; Butchart, Stuart H M; Hilton-Taylor, Craig; Hoffmann, Michael; Juffe-Bignoli, Diego; Kingston, Naomi; MacSharry, Brian; Parr, Mike; Perianin, Laurence; Regan, Eugenie C; Rodrigues, Ana S L; Rondinini, Carlo; Shennan-Farpon, Yara; Young, Bruce E

2016-02-16

Two processes for regional environmental assessment are currently underway: the Global Environment Outlook (GEO) and Intergovernmental Platform on Biodiversity and Ecosystem Services (IPBES). Both face constraints of data, time, capacity, and resources. To support these assessments, we disaggregate three global knowledge products according to their regions and subregions. These products are: The IUCN Red List of Threatened Species, Key Biodiversity Areas (specifically Important Bird &Biodiversity Areas [IBAs], and Alliance for Zero Extinction [AZE] sites), and Protected Planet. We present fourteen Data citations: numbers of species occurring and percentages threatened; numbers of endemics and percentages threatened; downscaled Red List Indices for mammals, birds, and amphibians; numbers, mean sizes, and percentage coverages of IBAs and AZE sites; percentage coverage of land and sea by protected areas; and trends in percentages of IBAs and AZE sites wholly covered by protected areas. These data will inform the regional/subregional assessment chapters on the status of biodiversity, drivers of its decline, and institutional responses, and greatly facilitate comparability and consistency between the different regional/subregional assessments.

Low Earth orbit communications satellite

NASA Technical Reports Server (NTRS)

Moroney, D.; Lashbrook, D.; Mckibben, B.; Gardener, N.; Rivers, T.; Nottingham, G.; Golden, B.; Barfield, B.; Bruening, J.; Wood, D.

1992-01-01

A current thrust in satellite communication systems considers a low-Earth orbiting constellations of satellites for continuous global coverage. Conceptual design studies have been done at the time of this design project by LORAL Aerospace Corporation under the program name GLOBALSTAR and by Motorola under their IRIDIUM program. This design project concentrates on the spacecraft design of the GLOBALSTAR low-Earth orbiting communication system. Overview information on the program was gained through the Federal Communications Commission licensing request. The GLOBALSTAR system consists of 48 operational satellites positioned in a Walker Delta pattern providing global coverage and redundancy. The operational orbit is 1389 km (750 nmi) altitude with eight planes of six satellites each. The orbital planes are spaced 45 deg., and the spacecraft are separated by 60 deg. within the plane. A Delta 2 launch vehicle is used to carry six spacecraft for orbit establishment. Once in orbit, the spacecraft will utilize code-division multiple access (spread spectrum modulation) for digital relay, voice, and radio determination satellite services (RDSS) yielding position determination with accuracy up to 200 meters.

A High-Coverage Yersinia pestis Genome from a Sixth-Century Justinianic Plague Victim

PubMed Central

Feldman, Michal; Harbeck, Michaela; Keller, Marcel; Spyrou, Maria A.; Rott, Andreas; Trautmann, Bernd; Scholz, Holger C.; Päffgen, Bernd; Peters, Joris; McCormick, Michael; Bos, Kirsten; Herbig, Alexander; Krause, Johannes

2016-01-01

The Justinianic Plague, which started in the sixth century and lasted to the mid eighth century, is thought to be the first of three historically documented plague pandemics causing massive casualties. Historical accounts and molecular data suggest the bacterium Yersinia pestis as its etiological agent. Here we present a new high-coverage (17.9-fold) Y. pestis genome obtained from a sixth-century skeleton recovered from a southern German burial site close to Munich. The reconstructed genome enabled the detection of 30 unique substitutions as well as structural differences that have not been previously described. We report indels affecting a lacl family transcription regulator gene as well as nonsynonymous substitutions in the nrdE, fadJ, and pcp genes, that have been suggested as plague virulence determinants or have been shown to be upregulated in different models of plague infection. In addition, we identify 19 false positive substitutions in a previously published lower-coverage Y. pestis genome from another archaeological site of the same time period and geographical region that is otherwise genetically identical to the high-coverage genome sequence reported here, suggesting low-genetic diversity of the plague during the sixth century in rural southern Germany. PMID:27578768

Dietary specialization is linked to reduced species durations in North American fossil canids

NASA Astrophysics Data System (ADS)

Balisi, Mairin; Casey, Corinna; Van Valkenburgh, Blaire

2018-04-01

How traits influence species persistence is a fundamental question in ecology, evolution and palaeontology. We test the relationship between dietary traits and both species duration and locality coverage over 40 million years in North American canids, a clade with considerable ecomorphological disparity and a dense fossil record. Because ecomorphological generalization-broad resource use-may enable species to withstand disturbance, we predicted that canids of average size and mesocarnivory would exhibit longer durations and wider distributions than specialized larger or smaller species. Second, because locality coverage might reflect dispersal ability and/or survivability in a range of habitats, we predicted that high coverage would correspond with longer durations. We find a nonlinear relationship between species duration and degree of carnivory: species at either end of the carnivory spectrum tend to have shorter durations than mesocarnivores. Locality coverage shows no relationship with size, diet or duration. To test whether generalization (medium size, mesocarnivory) corresponds to an adaptive optimum, we fit trait evolution models to previously generated canid phylogenies. Our analyses identify no single optimum in size or diet. Instead, the primary model of size evolution is a classic Cope's Rule increase over time, while dietary evolution does not conform to a single model.

Nano-enabled drug delivery: a research profile.

PubMed

Zhou, Xiao; Porter, Alan L; Robinson, Douglas K R; Shim, Min Suk; Guo, Ying

2014-07-01

Nano-enabled drug delivery (NEDD) systems are rapidly emerging as a key area for nanotechnology application. Understanding the status and developmental prospects of this area around the world is important to determine research priorities, and to evaluate and direct progress. Global research publication and patent databases provide a reservoir of information that can be tapped to provide intelligence for such needs. Here, we present a process to allow for extraction of NEDD-related information from these databases by involving topical experts. This process incorporates in-depth analysis of NEDD literature review papers to identify key subsystems and major topics. We then use these to structure global analysis of NEDD research topical trends and collaborative patterns, inform future innovation directions. This paper describes the process of how to derive nano-enabled drug delivery-related information from global research and patent databases in an effort to perform comprehensive global analysis of research trends and directions, along with collaborative patterns. Copyright © 2014 Elsevier Inc. All rights reserved.

Airborne Instrument Simulator for the Lidar Surface Topography (LIST) Mission

NASA Technical Reports Server (NTRS)

Yu, Anthony W.; Krainak, Michael A.; Harding, David J.; Abshire, James B.; Sun, Xiaoli; Cavanaugh, John; Valett, Susan; Ramos-Izquierdo, Luis

2010-01-01

In 2007, the National Research Council (NRC) completed its first decadal survey for Earth science at the request of NASA, NOAA, and USGS. The Lidar Surface Topography (LIST) mission is one of fifteen missions recommended by NRC, whose primary objectives are to map global topography and vegetation structure at 5 m spatial resolution, and to acquire global coverage with a few years. NASA Goddard conducted an initial mission concept study for the LIST mission 2007, and developed the initial measurement requirements for the mission.

Scientific motivation for ADM/Aeolus mission

NASA Astrophysics Data System (ADS)

Källén, Erland

2018-04-01

The ADM/Aeolus wind lidar mission will provide a global coverage of atmospheric wind profiles. Atmospheric wind observations are required for initiating weather forecast models and for predicting and monitoring long term climate change. Improved knowledge of the global wind field is widely recognised as fundamental to advancing the understanding and prediction of weather and climate. In particular over tropical areas there is a need for better wind data leading to improved medium range (3-10 days) weather forecasts over the whole globe.

Integrating social determinants of health in the universal health coverage monitoring framework.

PubMed

Vega, Jeanette; Frenz, Patricia

2013-12-01

Underpinning the global commitment to universal health coverage (UHC) is the fundamental role of health for well-being and sustainable development. UHC is proposed as an umbrella health goal in the post-2015 sustainable development agenda because it implies universal and equitable effective delivery of comprehensive health services by a strong health system, aligned with multiple sectors around the shared goal of better health. In this paper, we argue that social determinants of health (SDH) are central to both the equitable pursuit of healthy lives and the provision of health services for all and, therefore, should be expressly incorporated into the framework for monitoring UHC. This can be done by: (a) disaggregating UHC indicators by different measures of socioeconomic position to reflect the social gradient and the complexity of social stratification; and (b) connecting health indicators, both outcomes and coverage, with SDH and policies within and outside of the health sector. Not locating UHC in the context of action on SDH increases the risk of going down a narrow route that limits the right to health to coverage of services and financial protection.

Improved candidate generation and coverage analysis methods for design optimization of symmetric multi-satellite constellations

NASA Astrophysics Data System (ADS)

Matossian, Mark G.

1997-01-01

Much attention in recent years has focused on commercial telecommunications ventures involving constellations of spacecraft in low and medium Earth orbit. These projects often require investments on the order of billions of dollars (US$) for development and operations, but surprisingly little work has been published on constellation design optimization for coverage analysis, traffic simulation and launch sequencing for constellation build-up strategies. This paper addresses the two most critical aspects of constellation orbital design — efficient constellation candidate generation and coverage analysis. Inefficiencies and flaws in the current standard algorithm for constellation modeling are identified, and a corrected and improved algorithm is presented. In the 1970's, John Walker and G. V. Mozhaev developed innovative strategies for continuous global coverage using symmetric non-geosynchronous constellations. (These are sometimes referred to as rosette, or Walker constellations. An example is pictured above.) In 1980, the late Arthur Ballard extended and generalized the work of Walker into a detailed algorithm for the NAVSTAR/GPS program, which deployed a 24 satellite symmetric constellation. Ballard's important contribution was published in his "Rosette Constellations of Earth Satellites."

Paris Agreement on Climate Change: A Booster to Enable Sustainable Global Development and Beyond.

PubMed

Bhore, Subhash Janardhan

2016-11-14

The global warming and its adverse effects on the atmosphere, the biosphere, the lithosphere, and the hydrosphere are obvious. Based on this fact, the international community is fully convinced that we need to fix the problem urgently for our survival, good health, and wellbeing. The aim of this article is to promote the awareness about the United Nations (UN) historic 'Paris Agreement on Climate Change (PACC)' which entered into-force on 4 November 2016. The expected impact of PACC on the global average temperature rise by 2100 as well as its role in enabling accomplishment of global sustainable development goals (SDGs) for the people and planet is also highlighted.

Paris Agreement on Climate Change: A Booster to Enable Sustainable Global Development and Beyond

PubMed Central

Bhore, Subhash Janardhan

2016-01-01

The global warming and its adverse effects on the atmosphere, the biosphere, the lithosphere, and the hydrosphere are obvious. Based on this fact, the international community is fully convinced that we need to fix the problem urgently for our survival, good health, and wellbeing. The aim of this article is to promote the awareness about the United Nations (UN) historic ‘Paris Agreement on Climate Change (PACC)’ which entered into-force on 4 November 2016. The expected impact of PACC on the global average temperature rise by 2100 as well as its role in enabling accomplishment of global sustainable development goals (SDGs) for the people and planet is also highlighted. PMID:27854248

CrossTalk: The Journal of Defense Software Engineering. Volume 21, Number 3

DTIC Science & Technology

2008-03-01

describes essentials for requirements development and management. In addi- tion to providing training, eLearning and consulting services, she speaks at and...information, support sense- making, enable collaborative decision making, and effect changes in the physical environment. For example, the Global ...across layers, which enables effective use of resources and helps enforce security and confiden- tiality policies. Global Data Space DDS provides a

Army AL&T, October-December 2008

DTIC Science & Technology

2008-12-01

during the WIN-T technology demonstration Nov. 8, 2007, at Naval Air Engineering Station , Lakehurst, NJ. (U.S. Army photo by Russ Messeroll.) 16 OCTOBER...worldwide communications architecture, enabling connectivity from the global backbone to regional networks to posts/camps/ stations , and, lastly, to...Force Tracker. • Tacticomp™ wireless and Global Positioning System(GPS)-enabled hand-held computer. • One Station Remote Video Terminal. • Counter

Systematic Assessment of Seven Solvent and Solid-Phase Extraction Methods for Metabolomics Analysis of Human Plasma by LC-MS

NASA Astrophysics Data System (ADS)

Sitnikov, Dmitri G.; Monnin, Cian S.; Vuckovic, Dajana

2016-12-01

The comparison of extraction methods for global metabolomics is usually executed in biofluids only and focuses on metabolite coverage and method repeatability. This limits our detailed understanding of extraction parameters such as recovery and matrix effects and prevents side-by-side comparison of different sample preparation strategies. To address this gap in knowledge, seven solvent-based and solid-phase extraction methods were systematically evaluated using standard analytes spiked into both buffer and human plasma. We compared recovery, coverage, repeatability, matrix effects, selectivity and orthogonality of all methods tested for non-lipid metabolome in combination with reversed-phased and mixed-mode liquid chromatography mass spectrometry analysis (LC-MS). Our results confirmed wide selectivity and excellent precision of solvent precipitations, but revealed their high susceptibility to matrix effects. The use of all seven methods showed high overlap and redundancy which resulted in metabolite coverage increases of 34-80% depending on LC-MS method employed as compared to the best single extraction protocol (methanol/ethanol precipitation) despite 7x increase in MS analysis time and sample consumption. The most orthogonal methods to methanol-based precipitation were ion-exchange solid-phase extraction and liquid-liquid extraction using methyl-tertbutyl ether. Our results help facilitate rational design and selection of sample preparation methods and internal standards for global metabolomics.

Systematic Assessment of Seven Solvent and Solid-Phase Extraction Methods for Metabolomics Analysis of Human Plasma by LC-MS

PubMed Central

Sitnikov, Dmitri G.; Monnin, Cian S.; Vuckovic, Dajana

2016-01-01

The comparison of extraction methods for global metabolomics is usually executed in biofluids only and focuses on metabolite coverage and method repeatability. This limits our detailed understanding of extraction parameters such as recovery and matrix effects and prevents side-by-side comparison of different sample preparation strategies. To address this gap in knowledge, seven solvent-based and solid-phase extraction methods were systematically evaluated using standard analytes spiked into both buffer and human plasma. We compared recovery, coverage, repeatability, matrix effects, selectivity and orthogonality of all methods tested for non-lipid metabolome in combination with reversed-phased and mixed-mode liquid chromatography mass spectrometry analysis (LC-MS). Our results confirmed wide selectivity and excellent precision of solvent precipitations, but revealed their high susceptibility to matrix effects. The use of all seven methods showed high overlap and redundancy which resulted in metabolite coverage increases of 34–80% depending on LC-MS method employed as compared to the best single extraction protocol (methanol/ethanol precipitation) despite 7x increase in MS analysis time and sample consumption. The most orthogonal methods to methanol-based precipitation were ion-exchange solid-phase extraction and liquid-liquid extraction using methyl-tertbutyl ether. Our results help facilitate rational design and selection of sample preparation methods and internal standards for global metabolomics. PMID:28000704

Regional positioning using a low Earth orbit satellite constellation

NASA Astrophysics Data System (ADS)

Shtark, Tomer; Gurfil, Pini

2018-02-01

Global and regional satellite navigation systems are constellations orbiting the Earth and transmitting radio signals for determining position and velocity of users around the globe. The state-of-the-art navigation satellite systems are located in medium Earth orbits and geosynchronous Earth orbits and are characterized by high launching, building and maintenance costs. For applications that require only regional coverage, the continuous and global coverage that existing systems provide may be unnecessary. Thus, a nano-satellites-based regional navigation satellite system in Low Earth Orbit (LEO), with significantly reduced launching, building and maintenance costs, can be considered. Thus, this paper is aimed at developing a LEO constellation optimization and design method, using genetic algorithms and gradient-based optimization. The preliminary results of this study include 268 LEO constellations, aimed at regional navigation in an approximately 1000 km × 1000 km area centered at the geographic coordinates [30, 30] degrees. The constellations performance is examined using simulations, and the figures of merit include total coverage time, revisit time, and geometric dilution of precision (GDOP) percentiles. The GDOP is a quantity that determines the positioning solution accuracy and solely depends on the spatial geometry of the satellites. Whereas the optimization method takes into account only the Earth's second zonal harmonic coefficient, the simulations include the Earth's gravitational field with zonal and tesseral harmonics up to degree 10 and order 10, Solar radiation pressure, drag, and the lunisolar gravitational perturbation.

Hierarchical Merging and Large-Scale Structure Within the Horologium-Reticulum Supercluster

NASA Astrophysics Data System (ADS)

Fleenor, M. C.; Rose, J. A.

2003-12-01

The Horologium-Reticulum Supercluster (HRS) covers an area of more than 12 x 12 degrees on the sky centered at approximately α = 3h18m43s, δ = -50°01\\arcmin40\\arcsec. It is second only to the Shapley supercluster in terms of mass concentration in the local 300 Mpc. We have now obtained ˜1450 unpublished redshifts via multi-fiber spectroscopy in this area covering both global and localized regions. On a global scale, approximately 550 spectra of galaxies have been obtained using the six-degree field (6dF) instrument on the UK Schmidt Telescope at the Anglo Australian Observatory (25% coverage down to 17.5 BJ). Spectroscopic studies in the localized regions of the HRS were completed with the fibre optic coupled aperture plate system (FOCAP with 40\\arcmin FOV) on the Anglo-Australian Telescope (90% coverage down to 19.0 BJ). This increase of information doubles the amount of coverage compared to previous redshift data and provides a complementary picture of the area. With ˜3000 redshifts in this region, we are understanding the role of the supercluster environment in structure formation and evolution. Specifically, we are probing the dynamical and morphological characteristics of the HRS complex, comparing these with other known supercluster data for similarities, as well as evaluating the hierarchical merging scenario of structure formation as found in CDM N-body simulations.

Coverage and predictors of vaccination against 2012/13 seasonal influenza in Madrid, Spain

PubMed Central

Jiménez-García, Rodrigo; Esteban-Vasallo, María D; Rodríguez-Rieiro, Cristina; Hernandez-Barrera, Valentín; Domínguez-Berjón, MA Felicitas; Carrasco Garrido, Pilar; Lopez de Andres, Ana; Cameno Heras, Moises; Iniesta Fornies, Domingo; Astray-Mochales, Jenaro

2014-01-01

We aim to determine 2012–13 seasonal influenza vaccination coverage. Data were analyzed by age group and by coexistence of concomitant chronic conditions. Factors associated with vaccine uptake were identified. We also analyze a possible trend in vaccine uptake in post pandemic seasons. We used computerized immunization registries and clinical records of the entire population of the Autonomous Community of Madrid, Spain (6 284 128 persons) as data source. A total of 871 631 individuals were vaccinated (13.87%). Coverage for people aged ≥ 65 years was 56.57%. Global coverage in people with a chronic condition was 15.7% in children and 18.69% in adults aged 15–59 years. The variables significantly associated with a higher likelihood of being vaccinated in the 2012–13 campaign for the age groups studied were higher age, being Spanish-born, higher number of doses of seasonal vaccine received in previous campaigns, uptake of pandemic vaccination, and having a chronic condition. We conclude that vaccination coverage in persons aged <60 years with chronic conditions is less than acceptable. The very low coverage among children with chronic conditions calls for urgent interventions. Among those aged ≥60 years, uptake is higher but still far from optimal and seems to be descending in post-pandemic campaigns. For those aged ≥65 years the mean percentage of decrease from the 2009/10 to the actual campaign has been 12%. Computerized clinical and immunization registers are useful tools for providing rapid and detailed information about influenza vaccination coverage in the population. PMID:24280728

Coverage and predictors of vaccination against 2012/13 seasonal influenza in Madrid, Spain: analysis of population-based computerized immunization registries and clinical records.

PubMed

Jiménez-García, Rodrigo; Esteban-Vasallo, María D; Rodríguez-Rieiro, Cristina; Hernandez-Barrera, Valentín; Domínguez-Berjón, M A Felicitas; Carrasco Garrido, Pilar; Lopez de Andres, Ana; Cameno Heras, Moises; Iniesta Fornies, Domingo; Astray-Mochales, Jenaro

2014-01-01

We aim to determine 2012-13 seasonal influenza vaccination coverage. Data were analyzed by age group and by coexistence of concomitant chronic conditions. Factors associated with vaccine uptake were identified. We also analyze a possible trend in vaccine uptake in post pandemic seasons. We used computerized immunization registries and clinical records of the entire population of the Autonomous Community of Madrid, Spain (6,284,128 persons) as data source. A total of 871,631 individuals were vaccinated (13.87%). Coverage for people aged ≥ 65 years was 56.57%. Global coverage in people with a chronic condition was 15.7% in children and 18.69% in adults aged 15-59 years. The variables significantly associated with a higher likelihood of being vaccinated in the 2012-13 campaign for the age groups studied were higher age, being Spanish-born, higher number of doses of seasonal vaccine received in previous campaigns, uptake of pandemic vaccination, and having a chronic condition. We conclude that vaccination coverage in persons aged<60 years with chronic conditions is less than acceptable. The very low coverage among children with chronic conditions calls for urgent interventions. Among those aged ≥60 years, uptake is higher but still far from optimal and seems to be descending in post-pandemic campaigns. For those aged ≥65 years the mean percentage of decrease from the 2009/10 to the actual campaign has been 12%. Computerized clinical and immunization registers are useful tools for providing rapid and detailed information about influenza vaccination coverage in the population.

The Economic Value of Long-Lasting Insecticidal Nets and Indoor Residual Spraying Implementation in Mozambique.

PubMed

Lee, Bruce Y; Bartsch, Sarah M; Stone, Nathan T B; Zhang, Shufang; Brown, Shawn T; Chatterjee, Chandrani; DePasse, Jay V; Zenkov, Eli; Briët, Olivier J T; Mendis, Chandana; Viisainen, Kirsi; Candrinho, Baltazar; Colborn, James

2017-06-01

AbstractMalaria-endemic countries have to decide how much of their limited resources for vector control to allocate toward implementing long-lasting insecticidal nets (LLINs) versus indoor residual spraying (IRS). To help the Mozambique Ministry of Health use an evidence-based approach to determine funding allocation toward various malaria control strategies, the Global Fund convened the Mozambique Modeling Working Group which then used JANUS, a software platform that includes integrated computational economic, operational, and clinical outcome models that can link with different transmission models (in this case, OpenMalaria) to determine the economic value of vector control strategies. Any increase in LLINs (from 80% baseline coverage) or IRS (from 80% baseline coverage) would be cost-effective (incremental cost-effectiveness ratios ≤ $114/disability-adjusted life year averted). However, LLIN coverage increases tend to be more cost-effective than similar IRS coverage increases, except where both pyrethroid resistance is high and LLIN usage is low. In high-transmission northern regions, increasing LLIN coverage would be more cost-effective than increasing IRS coverage. In medium-transmission central regions, changing from LLINs to IRS would be more costly and less effective. In low-transmission southern regions, LLINs were more costly and less effective than IRS, due to low LLIN usage. In regions where LLINs are more cost-effective than IRS, it is worth considering prioritizing LLIN coverage and use. However, IRS may have an important role in insecticide resistance management and epidemic control. Malaria intervention campaigns are not a one-size-fits-all solution, and tailored approaches are necessary to account for the heterogeneity of malaria epidemiology.

Scaling up in international health: what are the key issues?

PubMed

Mangham, Lindsay J; Hanson, Kara

2010-03-01

The term 'scaling up' is now widely used in the international health literature, though it lacks an agreed definition. We review what is meant by scaling up in the context of changes in international health and development over the last decade. We argue that the notion of scaling up is primarily used to describe the ambition or process of expanding the coverage of health interventions, though the term has also referred to increasing the financial, human and capital resources required to expand coverage. We discuss four pertinent issues in scaling up the coverage of health interventions: the costs of scaling up coverage; constraints to scaling up; equity and quality concerns; and key service delivery issues when scaling up. We then review recent progress in scaling up the coverage of health interventions. This includes a considerable increase in the volume of aid, accompanied by numerous new health initiatives and financing mechanisms. There have also been improvements in health outcomes and some examples of successful large-scale programmes. Finally, we reflect on the importance of obtaining a better understanding of how to deliver priority health interventions at scale, the current emphasis on health system strengthening and the challenges of sustaining scaling up in the prevailing global economic environment.

A New Method for Estimating the Coverage of Mass Vaccination Campaigns Against Poliomyelitis From Surveillance Data

PubMed Central

O'Reilly, K. M.; Cori, A.; Durry, E.; Wadood, M. Z.; Bosan, A.; Aylward, R. B.; Grassly, N. C.

2015-01-01

Mass vaccination campaigns with the oral poliovirus vaccine targeting children aged <5 years are a critical component of the global poliomyelitis eradication effort. Monitoring the coverage of these campaigns is essential to allow corrective action, but current approaches are limited by their cross-sectional nature, nonrandom sampling, reporting biases, and accessibility issues. We describe a new Bayesian framework using data augmentation and Markov chain Monte Carlo methods to estimate variation in vaccination coverage from children's vaccination histories investigated during surveillance for acute flaccid paralysis. We tested the method using simulated data with at least 200 cases and were able to detect undervaccinated groups if they exceeded 10% of all children and temporal changes in coverage of ±10% with greater than 90% sensitivity. Application of the method to data from Pakistan for 2010–2011 identified undervaccinated groups within the Balochistan/Federally Administered Tribal Areas and Khyber Pakhtunkhwa regions, as well as temporal changes in coverage. The sizes of these groups are consistent with the multiple challenges faced by the program in these regions as a result of conflict and insecurity. Application of this new method to routinely collected data can be a useful tool for identifying poorly performing areas and assisting in eradication efforts. PMID:26568569

Adsorption of dextrin on hydrophobic minerals.

PubMed

Beaussart, Audrey; Mierczynska-Vasilev, Agnieszka; Beattie, David A

2009-09-01

The adsorption of dextrin on talc, molybdenite, and graphite (three naturally hydrophobic minerals) has been compared. Adsorption isotherms and in situ tapping mode atomic force microscope (TMAFM) imaging have enabled polymer adsorbed amount and morphology of the adsorbed layer (area coverage and polymer domain size) to be determined and also the amount of hydration water in the structure of the adsorbed layer. The effect of the polymer on the mineral contact angles, measured by the captive bubble method on cleaved mineral surfaces, indicates clear correlations between the hydrophobicity reduction of the minerals, the adsorbed amount, and the surface coverage of the adsorbed polymer. Predictions of the flotation recovery of the treated mineral phases have been confirmed by performing batch flotation experiments. The influence of the polymer surface coverage on flotation recovery has highlighted the importance of this key parameter in the predictions of depressant efficiency. The roles of the initial hydrophobicity and the surface structure of the mineral basal plane in determining adsorption parameters and flotation response of the polymer-treated minerals are also discussed.

Footprint Database and web services for the Herschel space observatory

NASA Astrophysics Data System (ADS)

Verebélyi, Erika; Dobos, László; Kiss, Csaba

2015-08-01

Using all telemetry and observational meta-data, we created a searchable database of Herschel observation footprints. Data from the Herschel space observatory is freely available for everyone but no uniformly processed catalog of all observations has been published yet. As a first step, we unified the data model for all three Herschel instruments in all observation modes and compiled a database of sky coverage information. As opposed to methods using a pixellation of the sphere, in our database, sky coverage is stored in exact geometric form allowing for precise area calculations. Indexing of the footprints allows for very fast search among observations based on pointing, time, sky coverage overlap and meta-data. This enables us, for example, to find moving objects easily in Herschel fields. The database is accessible via a web site and also as a set of REST web service functions which makes it usable from program clients like Python or IDL scripts. Data is available in various formats including Virtual Observatory standards.

Web Coverage Service Challenges for NASA's Earth Science Data

NASA Technical Reports Server (NTRS)

Cantrell, Simon; Khan, Abdul; Lynnes, Christopher

2017-01-01

In an effort to ensure that data in NASA's Earth Observing System Data and Information System (EOSDIS) is available to a wide variety of users through the tools of their choice, NASA continues to focus on exposing data and services using standards based protocols. Specifically, this work has focused recently on the Web Coverage Service (WCS). Experience has been gained in data delivery via GetCoverage requests, starting out with WCS v1.1.1. The pros and cons of both the version itself and different implementation approaches will be shared during this session. Additionally, due to limitations with WCS v1.1.1 ability to work with NASA's Earth science data, this session will also discuss the benefit of migrating to WCS 2.0.1 with EO-x to enrich this capability to meet a wide range of anticipated user's needs This will enable subsetting and various types of data transformations to be performed on a variety of EOS data sets.

The opposition of Mars, 1999

NASA Astrophysics Data System (ADS)

McKim, R. J.

2007-12-01

The 1999 martian apparition was followed by BAA members while Mars Global Surveyor was monitoring the planet from martian orbit. The planet's surface showed little change from 1997, indicating the absence of any great dust storm since solar conjunction. The long period of telescopic coverage enabled us to conclude that neither was there any planet-encircling storm in the southern martian spring or summer in 1999-2000. Three small telescopic storms were followed along the Valles Marineris, and two were seen at the edge of the summer N. polar cap. Dust storms commencing at the historically rarely-active Margaritifer Sinus emergence site (MGS data) point to ongoing changes in the fallout pattern of atmospheric dust. White cloud activity was high before and around opposition time - in northern midsummer - with morning and evening limb hazes, the equatorial cloud band (ECB) and orographic clouds. The ECB 'season' was identical to 1997, pointing to an equally low level of atmospheric dust-loading. Comparison with historical records suggests that the seasonal 'wave of darkening' may be partly attributable to the annual disappearance of the ECB. This report covers the period 1998 September 12 (Ls = 28°) to 2000 March 13 (Ls = 318°)

Synthesis of phylogeny and taxonomy into a comprehensive tree of life

PubMed Central

Hinchliff, Cody E.; Smith, Stephen A.; Allman, James F.; Burleigh, J. Gordon; Chaudhary, Ruchi; Coghill, Lyndon M.; Crandall, Keith A.; Deng, Jiabin; Drew, Bryan T.; Gazis, Romina; Gude, Karl; Hibbett, David S.; Katz, Laura A.; Laughinghouse, H. Dail; McTavish, Emily Jane; Midford, Peter E.; Owen, Christopher L.; Ree, Richard H.; Rees, Jonathan A.; Soltis, Douglas E.; Williams, Tiffani; Cranston, Karen A.

2015-01-01

Reconstructing the phylogenetic relationships that unite all lineages (the tree of life) is a grand challenge. The paucity of homologous character data across disparately related lineages currently renders direct phylogenetic inference untenable. To reconstruct a comprehensive tree of life, we therefore synthesized published phylogenies, together with taxonomic classifications for taxa never incorporated into a phylogeny. We present a draft tree containing 2.3 million tips—the Open Tree of Life. Realization of this tree required the assembly of two additional community resources: (i) a comprehensive global reference taxonomy and (ii) a database of published phylogenetic trees mapped to this taxonomy. Our open source framework facilitates community comment and contribution, enabling the tree to be continuously updated when new phylogenetic and taxonomic data become digitally available. Although data coverage and phylogenetic conflict across the Open Tree of Life illuminate gaps in both the underlying data available for phylogenetic reconstruction and the publication of trees as digital objects, the tree provides a compelling starting point for community contribution. This comprehensive tree will fuel fundamental research on the nature of biological diversity, ultimately providing up-to-date phylogenies for downstream applications in comparative biology, ecology, conservation biology, climate change, agriculture, and genomics. PMID:26385966

Synthesis of phylogeny and taxonomy into a comprehensive tree of life.

PubMed

Hinchliff, Cody E; Smith, Stephen A; Allman, James F; Burleigh, J Gordon; Chaudhary, Ruchi; Coghill, Lyndon M; Crandall, Keith A; Deng, Jiabin; Drew, Bryan T; Gazis, Romina; Gude, Karl; Hibbett, David S; Katz, Laura A; Laughinghouse, H Dail; McTavish, Emily Jane; Midford, Peter E; Owen, Christopher L; Ree, Richard H; Rees, Jonathan A; Soltis, Douglas E; Williams, Tiffani; Cranston, Karen A

2015-10-13

Reconstructing the phylogenetic relationships that unite all lineages (the tree of life) is a grand challenge. The paucity of homologous character data across disparately related lineages currently renders direct phylogenetic inference untenable. To reconstruct a comprehensive tree of life, we therefore synthesized published phylogenies, together with taxonomic classifications for taxa never incorporated into a phylogeny. We present a draft tree containing 2.3 million tips-the Open Tree of Life. Realization of this tree required the assembly of two additional community resources: (i) a comprehensive global reference taxonomy and (ii) a database of published phylogenetic trees mapped to this taxonomy. Our open source framework facilitates community comment and contribution, enabling the tree to be continuously updated when new phylogenetic and taxonomic data become digitally available. Although data coverage and phylogenetic conflict across the Open Tree of Life illuminate gaps in both the underlying data available for phylogenetic reconstruction and the publication of trees as digital objects, the tree provides a compelling starting point for community contribution. This comprehensive tree will fuel fundamental research on the nature of biological diversity, ultimately providing up-to-date phylogenies for downstream applications in comparative biology, ecology, conservation biology, climate change, agriculture, and genomics.

OMPS TC EDR Algorithm: Improvement and Verification

NASA Astrophysics Data System (ADS)

Novicki, M.; Sen, B.; Hao, X.; Qu, J. J.

2009-12-01

The Ozone Mapper and Profiler Suite (OMPS) is scheduled to be launched on the NPOESS Preparatory Project (NPP) platform in early 2011. The OMPS will continue monitoring ozone from space, using three instruments, namely the Total Column Mapper (heritage: TOMS), the Nadir Profiler (heritage: SBUV) and the Limb Profiler (heritage: SOLSE/LORE). The Total Column Mapper (TC) sensor images the Earth through a slit, nadir-cell horizontally spaced at 49.5 km cross-track with an along-track reporting interval of 50 km. The total field of view (FOV) cross track is 110 degrees to provide daily global coverage. The TC sensor, a grating spectrometer, provides 0.45 nm spectral sampling across the wavelength range of 300-380 nm. The calibration stability, which is essential to enable long-term ozone monitoring, is maintained by periodic observations of the Sun, using a diffuser to redirect the solar irradiance into the sensor. We describe the data analysis method being presently implemented to retrieve the total column ozone Earth Data Record (EDR) from the radiance data measured by the TC sensor. We discuss the software changes, the test data used to verify the functional performance and the test results.

OMPS SDR Calibration and Validation

NASA Astrophysics Data System (ADS)

Sen, B.; Done, J.; Buss, R.; Jaross, G. R.; Kelly, T. J.

2009-12-01

The Ozone Mapper and Profiler Suite (OMPS) is scheduled to be launched on the NPOESS Preparatory Project (NPP) platform in early 2011. The OMPS will continue monitoring ozone from space, using three instruments, namely the Total Column Mapper (heritage: TOMS), the Nadir Profiler (heritage: SBUV) and the Limb Profiler (heritage: SOLSE/LORE). The Total Column Mapper (TC) sensor images the Earth through a slit, nadir-cell horizontally spaced at 49.5 km cross-track with an along-track reporting interval of 50 km. The total field of view (FOV) cross-track is 110 degree to provide daily global coverage. The TC sensor, a grating spectrometer, provides 0.45 nm spectral sampling across the wavelength range of 300-380 nm. The calibration stability, which is essential to enable long-term ozone monitoring, is maintained by periodic observations of the Sun, using a diffuser to redirect the solar irradiance into the sensor. We describe the plans to calibrate the TC sensor and validate the radiance data (TC Sensor Data Record or TC SDR) after launch. We discuss the measurements planned during the Intensive Cal/Val (ICV) phase of NPP mission, the data analysis methodology and results from the analysis of OMPS calibration measurements.

Networks of energetic and metabolic interactions define dynamics in microbial communities.

PubMed

Embree, Mallory; Liu, Joanne K; Al-Bassam, Mahmoud M; Zengler, Karsten

2015-12-15

Microorganisms form diverse communities that have a profound impact on the environment and human health. Recent technological advances have enabled elucidation of community diversity at high resolution. Investigation of microbial communities has revealed that they often contain multiple members with complementing and seemingly redundant metabolic capabilities. An understanding of the communal impacts of redundant metabolic capabilities is currently lacking; specifically, it is not known whether metabolic redundancy will foster competition or motivate cooperation. By investigating methanogenic populations, we identified the multidimensional interspecies interactions that define composition and dynamics within syntrophic communities that play a key role in the global carbon cycle. Species-specific genomes were extracted from metagenomic data using differential coverage binning. We used metabolic modeling leveraging metatranscriptomic information to reveal and quantify a complex intertwined system of syntrophic relationships. Our results show that amino acid auxotrophies create additional interdependencies that define community composition and control carbon and energy flux through the system while simultaneously contributing to overall community robustness. Strategic use of antimicrobials further reinforces this intricate interspecies network. Collectively, our study reveals the multidimensional interactions in syntrophic communities that promote high species richness and bolster community stability during environmental perturbations.

FINESSE & CASE: Two Proposed Transiting Exoplanet Missions

NASA Astrophysics Data System (ADS)

Zellem, Robert Thomas; FINESSE and CASE Science Team

2018-01-01

The FINESSE mission concept and the proposed CASE Mission of Opportunity, both recently selected by NASA’s Explorer program to proceed to Step 2, would conduct the first characterizations of exoplanet atmospheres for a statistically significant population. FINESSE would determine whether our Solar System is typical or exceptional, the key characteristics of the planet formation mechanism, and what establishes global planetary climate by spectroscopically surveying 500 exoplanets, ranging from terrestrials with extended atmospheres to sub-Neptunes to gas giants. FINESSE’s broad, instantaneous spectral coverage from 0.5-5 microns and capability to survey hundreds of exoplanets would enable follow-up exploration of TESS discoveries and provide a broader context for interpreting detailed JWST observations. Similarly, CASE, a NASA Mission of Opportunity contribution to ESA’s dedicated transiting exoplanet spectroscopy mission ARIEL, would observe 1000 warm transiting gas giants, Neptunes, and super-Earths, using visible to near-IR photometry and spectroscopy. CASE would quantify the occurrence rate of atmospheric aerosols (clouds and hazes) and measure the geometric albedos of the targets in the ARIEL survey. Thus, with the selection of either of these two missions, NASA would ensure access to critical data for the U.S. exoplanet science community.

The BGAN extension programme

NASA Astrophysics Data System (ADS)

Rivera, Juan J.; Trachtman, Eyal; Richharia, Madhavendra

2005-11-01

Mobile satellite telecommunications systems have undergone an enormous evolution in the last decades, with the interest in having advanced telecommunications services available on demand, anywhere and at any time, leading to incredible advances. The demand for braodband data is therefore rapidly gathering pace, but current solutions are finding it increasingly difficult to combine large bandwidth with ubiquitous coverage, reliability and portability. The BGAN (Broadband Global Area Network) system, designed to operate with the Inmarsat-4 satellites, provides breakthrough services that meet all of these requirements. It will enable broadband connection on the move, delivering all the key tools of the modern office. Recognising the great impact that Inmarsat's BGAN system will have on the European satellite communications industry, and the benefits that it will bring to a wide range of European industries, in 2003 ESA initiated the "BGAN Extension" project. Its primary goals are to provide the full range of BGAN services to truly mobile platforms, operating in aeronautical, vehicular and maritime environments, and to introduce a multicast service capability. The project is supported by the ARTES Programme which establishes a collaboration agreement between ESA, Inmarsat and a group of key industrial and academic institutions which includes EMS, Logica, Nera and the University of Surrey (UK).

Mapping a Global Agenda for Adolescent Health

PubMed Central

Patton, George C.; Viner, Russell M.; Linh, Le Cu; Ameratunga, Shanthi; Fatusi, Adesegun O.; Ferguson, B. Jane; Patel, Vikram

2016-01-01

Major changes in health are underway in many low- and middle-income countries that are likely to bring greater focus on adolescents. This commentary, based on a 2009 London meeting, considers the need for strategic information for future global initiatives in adolescent health. Current coverage of adolescent health in global data collections is patchy. There is both the need and scope to extend existing collections into the adolescent years as well as achieve greater harmonization of measures between surveys. The development of a core set of global adolescent health indicators would aid this process. Other important tasks include adapting and testing interventions in low- and middle-income countries, growing research capacity in those settings, better communication of research from those countries, and building structures to implement future global initiatives. A global agenda needs more than good data, but sound information about adolescent health and its social and environmental determinants, will be important in both advocacy and practice. PMID:20970076

Agonistic TAM-163 antibody targeting tyrosine kinase receptor-B: applying mechanistic modeling to enable preclinical to clinical translation and guide clinical trial design.

PubMed

Vugmeyster, Yulia; Rohde, Cynthia; Perreault, Mylene; Gimeno, Ruth E; Singh, Pratap

2013-01-01

TAM-163, an agonist monoclonal antibody targeting tyrosine receptor kinase-B (TrkB), is currently being investigated as a potential body weight modulatory agent in humans. To support the selection of the dose range for the first-in-human (FIH) trial of TAM-163, we conducted a mechanistic analysis of the pharmacokinetic (PK) and pharmacodynamic (PD) data (e.g., body weight gain) obtained in lean cynomolgus and obese rhesus monkeys following single doses ranging from 0.3 to 60 mg/kg. A target-mediated drug disposition (TMDD) model was used to describe the observed nonlinear PK and Emax approach was used to describe the observed dose-dependent PD effect. The TMDD model development was supported by the experimental determination of the binding affinity constant (9.4 nM) and internalization rate of the drug-target complex (2.08 h(-1)). These mechanistic analyses enabled linking of exposure, target (TrkB) coverage, and pharmacological activity (e.g., PD) in monkeys, and indicated that ≥ 38% target coverage (time-average) was required to achieve significant body weight gain in monkeys. Based on the scaling of the TMDD model from monkeys to humans and assuming similar relationship between the target coverage and pharmacological activity between monkey and humans, subcutaneous (SC) doses of 1 and 15 mg/kg in humans were projected to be the minimally and the fully pharmacologically active doses, respectively. Based on the minimal anticipated biological effect level (MABEL) approach for starting dose selection, the dose of 0.05 mg/kg (3 mg for a 60 kg human) SC was recommended as the starting dose for FIH trials, because at this dose level<10% target coverage was projected at Cmax (and all other time points). This study illustrates a rational mechanistic approach for the selection of FIH dose range for a therapeutic protein with a complex model of action.

Fate and Effects of Anthropogenic Chemicals in Mangrove Ecosystems: A Review

EPA Science Inventory

The role of anthropogenic chemicals in the decline of plant-dominated, fringe ecosystems such as mangroves is important to understand. Mangrove global coverage has been reduced approximately 50% in recent years and the presence of toxic chemicals may be a contributing factor. T...

The CYGNSS flight segment; A major NASA science mission enabled by micro-satellite technology

NASA Astrophysics Data System (ADS)

Rose, R.; Ruf, C.; Rose, D.; Brummitt, M.; Ridley, A.

While hurricane track forecasts have improved in accuracy by ~50% since 1990, there has been essentially no improvement in the accuracy of intensity prediction. This lack of progress is thought to be caused by inadequate observations and modeling of the inner core due to two causes: 1) much of the inner core ocean surface is obscured from conventional remote sensing instruments by intense precipitation in the inner rain bands and 2) the rapidly evolving stages of the tropical cyclone (TC) life cycle are poorly sampled in time by conventional polar-orbiting, wide-swath surface wind imagers. NASA's most recently awarded Earth science mission, the NASA EV-2 Cyclone Global Navigation Satellite System (CYGNSS) has been designed to address these deficiencies by combining the all-weather performance of GNSS bistatic ocean surface scatterometry with the sampling properties of a satellite constellation. This paper provides an overview of the CYGNSS flight segment requirements, implementation, and concept of operations for the CYGNSS constellation; consisting of 8 microsatellite-class spacecraft (<; 100kg) each hosting a GNSS receiver, operating in a 500 km orbit, inclined at 35° to provide 70% coverage of the historical TC track. The CYGNSS mission is enabled by modern electronic technology; it is an example of how nanosatellite technology can be applied to replace traditional "old school" solutions at significantly reduced cost while providing an increase in performance. This paper provides an overview of how we combined a reliable space-flight proven avionics design with selected microsatellite components to create an innovative, low-cost solution for a mainstream science investigation.

Posterosuperior Placement of a Standard-Sized Cup at the True Acetabulum in Acetabular Reconstruction of Developmental Dysplasia of the Hip With High Dislocation.

PubMed

Xu, Jiawei; Xu, Chen; Mao, Yuanqing; Zhang, Jincheng; Li, Huiwu; Zhu, Zhenan

2016-06-01

We sought to evaluate posterosuperior placement of the acetabular component at the true acetabulum during acetabular reconstruction in patients with Crowe type-IV developmental dysplasia of the hip. Using pelvic computed tomography and image processing, we developed a two-dimensional mapping technique to demonstrate the distribution of preoperative three-dimensional cup coverage at the true acetabulum, determined the postoperative location of the acetabular cup, and calculated postoperative three-dimensional coverage for 16 Crowe type-IV dysplastic hips in 14 patients with a mean age of 52 years (33-78 years) who underwent total hip arthroplasty. Mean follow-up was 6.3 years (5.5-7.3 years). On preoperative mapping, the maximum three-dimensional coverage using a 44-mm cup was 87.31% (77.36%-98.14%). Mapping enabled the successful replacement of 16 hips using a mean cup size of 44.13 mm (42-46 mm) with posterosuperior placement of the cup. Early weight-bearing and no prosthesis revision or loosening during follow-up were achieved in all patients. The postoperative two-dimensional coverage on anteroposterior radiographs and three-dimensional coverage were 96.15% (89.49%-100%) and 83.42% (71.81%-98.50%), respectively. This technique may improve long-term implant survival in patients with Crowe-IV developmental dysplasia of the hip undergoing total hip arthroplasty by allowing the use of durable bearings, increasing host bone coverage, ensuring initial stability, and restoring the normal hip center. Copyright © 2015 Elsevier Inc. All rights reserved.

Universal health coverage in Turkey: enhancement of equity.

PubMed

Atun, Rifat; Aydın, Sabahattin; Chakraborty, Sarbani; Sümer, Safir; Aran, Meltem; Gürol, Ipek; Nazlıoğlu, Serpil; Ozgülcü, Senay; Aydoğan, Ulger; Ayar, Banu; Dilmen, Uğur; Akdağ, Recep

2013-07-06

Turkey has successfully introduced health system changes and provided its citizens with the right to health to achieve universal health coverage, which helped to address inequities in financing, health service access, and health outcomes. We trace the trajectory of health system reforms in Turkey, with a particular emphasis on 2003-13, which coincides with the Health Transformation Program (HTP). The HTP rapidly expanded health insurance coverage and access to health-care services for all citizens, especially the poorest population groups, to achieve universal health coverage. We analyse the contextual drivers that shaped the transformations in the health system, explore the design and implementation of the HTP, identify the factors that enabled its success, and investigate its effects. Our findings suggest that the HTP was instrumental in achieving universal health coverage to enhance equity substantially, and led to quantifiable and beneficial effects on all health system goals, with an improved level and distribution of health, greater fairness in financing with better financial protection, and notably increased user satisfaction. After the HTP, five health insurance schemes were consolidated to create a unified General Health Insurance scheme with harmonised and expanded benefits. Insurance coverage for the poorest population groups in Turkey increased from 2·4 million people in 2003, to 10·2 million in 2011. Health service access increased across the country-in particular, access and use of key maternal and child health services improved to help to greatly reduce the maternal mortality ratio, and under-5, infant, and neonatal mortality, especially in socioeconomically disadvantaged groups. Several factors helped to achieve universal health coverage and improve outcomes. These factors include economic growth, political stability, a comprehensive transformation strategy led by a transformation team, rapid policy translation, flexible implementation with continuous learning, and simultaneous improvements in the health system, on both the demand side (increased health insurance coverage, expanded benefits, and reduced cost-sharing) and the supply side (expansion of infrastructure, health human resources, and health services). Copyright © 2013 Elsevier Ltd. All rights reserved.

Semantic Data Integration and Ontology Use within the Global Earth Observation System of Systems (GEOSS) Global Water Cycle Data Integration System

NASA Astrophysics Data System (ADS)

Pozzi, W.; Fekete, B.; Piasecki, M.; McGuinness, D.; Fox, P.; Lawford, R.; Vorosmarty, C.; Houser, P.; Imam, B.

2008-12-01

The inadequacies of water cycle observations for monitoring long-term changes in the global water system, as well as their feedback into the climate system, poses a major constraint on sustainable development of water resources and improvement of water management practices. Hence, The Group on Earth Observations (GEO) has established Task WA-08-01, "Integration of in situ and satellite data for water cycle monitoring," an integrative initiative combining different types of satellite and in situ observations related to key variables of the water cycle with model outputs for improved accuracy and global coverage. This presentation proposes development of the Rapid, Integrated Monitoring System for the Water Cycle (Global-RIMS)--already employed by the GEO Global Terrestrial Network for Hydrology (GTN-H)--as either one of the main components or linked with the Asian system to constitute the modeling system of GEOSS for water cycle monitoring. We further propose expanded, augmented capability to run multiple grids to embrace some of the heterogeneous methods and formats of the Earth Science, Hydrology, and Hydraulic Engineering communities. Different methodologies are employed by the Earth Science (land surface modeling), the Hydrological (GIS), and the Hydraulic Engineering Communities; with each community employing models that require different input data. Data will be routed as input variables to the models through web services, allowing satellite and in situ data to be integrated together within the modeling framework. Semantic data integration will provide the automation to enable this system to operate in near-real-time. Multiple data collections for ground water, precipitation, soil moisture satellite data, such as SMAP, and lake data will require multiple low level ontologies, and an upper level ontology will permit user-friendly water management knowledge to be synthesized. These ontologies will have to have overlapping terms mapped and linked together. so that they can cover an even wider net of data sources. The goal is to develop the means to link together the upper level and lower level ontologies and to have these registered within the GEOSS Registry. Actual operational ontologies that would link to models or link to data collections containing input variables required by models would have to be nested underneath this top level ontology, analogous to the mapping that has been carried out among ontologies within GEON.

Diarrhoeal diseases and the global health agenda: measuring and changing priority.

PubMed

Bump, Jesse B; Reich, Michael R; Johnson, Anne M

2013-12-01

We investigate priority setting and the global health agenda by analysing the control of diarrhoeal diseases (CDD). CDD was one of the 'twin engines' of the 1980s' child survival movement, but now has a low priority on the global health agenda, even though diarrhoeal diseases still claim around 1.5 million children annually. In this article, we develop a framework and four indicators of priority to measure CDD's overall prominence on the global health agenda over the last three decades: trends in treatment coverage, changes in perceived priority, changes in financial support and institutional involvement and bibliographic trends. We find that CDD's priority is now one-sixth to one-third of its level in 1985. We then use political analysis to suggest strategies for reframing CDD as an issue and promoting its priority on the global health agenda.

Forecasting Plant Productivity and Health Using Diffuse-to-Global Irradiance Ratios Extracted from the OMI Aerosol Product

NASA Technical Reports Server (NTRS)

Knowlton, Kelly; Andrews, Jane C.; Ryan, Robert E.

2007-01-01

Atmospheric aerosols are a major contributor to diffuse irradiance. This Candidate Solution suggests using the OMI (Ozone Monitoring Instrument) aerosol product as input into a radiative transfer model, which would calculate the ratio of diffuse to global irradiance at the Earth s surface. This ratio can significantly influence the rate of photosynthesis in plants; increasing the ratio of diffuse to global irradiance can accelerate photosynthesis, resulting in greater plant productivity. Accurate values of this ratio could be useful in predicting crop productivity, thereby improving forecasts of regional food resources. However, disagreements exist between diffuse-to-global irradiance values measured by different satellites and ground sensors. OMI, with its unique combination of spectral bands, high resolution, and daily global coverage, may be able to provide more accurate aerosol measurements than other comparable sensors.

Regional and global forcing of glacier retreat during the last deglaciation.

PubMed

Shakun, Jeremy D; Clark, Peter U; He, Feng; Lifton, Nathaniel A; Liu, Zhengyu; Otto-Bliesner, Bette L

2015-08-21

The ongoing retreat of glaciers globally is one of the clearest manifestations of recent global warming associated with rising greenhouse gas concentrations. By comparison, the importance of greenhouse gases in driving glacier retreat during the most recent deglaciation, the last major interval of global warming, is unclear due to uncertainties in the timing of retreat around the world. Here we use recently improved cosmogenic-nuclide production-rate calibrations to recalculate the ages of 1,116 glacial boulders from 195 moraines that provide broad coverage of retreat in mid-to-low-latitude regions. This revised history, in conjunction with transient climate model simulations, suggests that while several regional-scale forcings, including insolation, ice sheets and ocean circulation, modulated glacier responses regionally, they are unable to account for global-scale retreat, which is most likely related to increasing greenhouse gas concentrations.

High resolution age-structured mapping of childhood vaccination coverage in low and middle income countries.

PubMed

Utazi, C Edson; Thorley, Julia; Alegana, Victor A; Ferrari, Matthew J; Takahashi, Saki; Metcalf, C Jessica E; Lessler, Justin; Tatem, Andrew J

2018-03-14

The expansion of childhood vaccination programs in low and middle income countries has been a substantial public health success story. Indicators of the performance of intervention programmes such as coverage levels and numbers covered are typically measured through national statistics or at the scale of large regions due to survey design, administrative convenience or operational limitations. These mask heterogeneities and 'coldspots' of low coverage that may allow diseases to persist, even if overall coverage is high. Hence, to decrease inequities and accelerate progress towards disease elimination goals, fine-scale variation in coverage should be better characterized. Using measles as an example, cluster-level Demographic and Health Surveys (DHS) data were used to map vaccination coverage at 1 km spatial resolution in Cambodia, Mozambique and Nigeria for varying age-group categories of children under five years, using Bayesian geostatistical techniques built on a suite of publicly available geospatial covariates and implemented via Markov Chain Monte Carlo (MCMC) methods. Measles vaccination coverage was found to be strongly predicted by just 4-5 covariates in geostatistical models, with remoteness consistently selected as a key variable. The output 1 × 1 km maps revealed significant heterogeneities within the three countries that were not captured using province-level summaries. Integration with population data showed that at the time of the surveys, few districts attained the 80% coverage, that is one component of the WHO Global Vaccine Action Plan 2020 targets. The elimination of vaccine-preventable diseases requires a strong evidence base to guide strategies and inform efficient use of limited resources. The approaches outlined here provide a route to moving beyond large area summaries of vaccination coverage that mask epidemiologically-important heterogeneities to detailed maps that capture subnational vulnerabilities. The output datasets are built on open data and methods, and in flexible format that can be aggregated to more operationally-relevant administrative unit levels. Copyright © 2018 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Crude childhood vaccination coverage in West Africa: Trends and predictors of completeness.

PubMed

Kazungu, Jacob S; Adetifa, Ifedayo M O

2017-02-15

Background : Africa has the lowest childhood vaccination coverage worldwide. If the full benefits of childhood vaccination programmes are to be enjoyed in sub-Saharan Africa, all countries need to improve on vaccine delivery to achieve and sustain high coverage. In this paper, we review trends in vaccination coverage, dropouts between vaccine doses and explored the country-specific predictors of complete vaccination in West Africa.  Methods : We utilized datasets from the Demographic and Health Surveys Program, available for Benin, Burkina Faso, The Gambia, Ghana, Guinea, Cote d'Ivoire, Liberia, Mali, Niger, Nigeria, Senegal, Sierra Leone and Togo, to obtain coverage for Bacillus Calmette-Guerin, polio, measles, and diphtheria, pertussis and tetanus (DPT) vaccines in children aged 12 - 23 months. We also calculated the DPT1-to-DPT3 and DPT1-to-measles dropouts, and proportions of the fully immunised child (FIC). Factors predictive of FIC were explored using Chi-squared tests and multivariable logistic regression.  Results : Overall, there was a trend of increasing vaccination coverage. The proportion of FIC varied significantly by country (range 24.1-81.4%, mean 49%). DPT1-to-DPT3 dropout was high (range 5.1% -33.9%, mean 16.3%). Similarly, DPT1-measles dropout exceeded 10% in all but four countries. Although no single risk factor was consistently associated with FIC across these countries, maternal education, delivery in a health facility, possessing a vaccine card and a recent post delivery visit to a health facility were the key predictors of complete vaccination.  Conclusions : The low numbers of fully immunised children and high dropout between vaccine doses highlights weaknesses and the need to strengthen the healthcare and routine immunization delivery systems in this region. Country-specific correlates of complete vaccination should be explored further to identify interventions required to increase vaccination coverage. Despite the promise of an increasing trend in vaccination coverage in West African countries, more effort is required to attain and maintain global vaccination coverage targets.

Lunar Orbiter Laser Altimeter (LOLA) Data: Lunar Topography and Surface Properties After 7 Years

NASA Astrophysics Data System (ADS)

Neumann, G. A.; Mazarico, E.; Lemoine, F. G.; Sun, X.; Head, J. W., III; Barker, M. K.; Jha, K.; Mao, D.; Torrence, M. H.; Smith, D. E.; Zuber, M. T.

2016-12-01

The LOLA altimeter on LRO has collected data on 31,500 orbits of the Moon since June 2009, firing 4.1 billion laser pulses split into 5 beams. Nearly 7 billion lunar altimetric bounce points have been geolocated with 0.5-m radial accuracy and 10 m total position errors using high-resolution gravity fields from GRAIL combined with radiometric tracking and one-way laser ranging, followed by crossover analysis. The altimetric data are resampled onto uniformly-spaced grids at resolutions down to the 5-m-diameter footprint scale of the LOLA beams where coverage permits. Originally flown to ensure safe landing and to provide a precise global geodetic grid on the Moon, ongoing analysis of LOLA data has enabled the measurement of the centimeter-level lunar tides, the survey of regions in permanent shadow and near-total solar illumination, and addressed problems of volcanology, tectonism, impact cratering, lunar chronology, mineralogy, crustal and interior structure, regolith evolution, nature and evolution of volatiles, surface roughness and slope interactions with particles. Active measurement of the surface reflectance at zero phase has suggested the presence of lunar frost in the coldest regions poleward of 80° N/S while passive measurements of the lunar phase function at 1064 nm wavelength have extended knowledge of lunar photometry in the near-infrared. Imperfections in topographic knowledge at the meter level arise from the need for interpolation within gaps, from misclassification of noise returns, and from residual orbital and attitude errors. Continued observations in the Extended Mission phases address these issues, while classification of ground returns is assisted by increasingly precise digital elevation models produced by stereographic analysis of data from the LRO cameras and the Kaguya Terrain Camera (e.g., imbrium.mit.edu/EXTRAS/SLDEM2015). The lower periapse altitude during the most recent mission year, together with changes in orbital inclination, enables more frequent observations of reflectance and temporal coverage of surface properties in the permanently-shadowed regions at 85-87° S, such as Cabeus, than were obtained in the first mission years. We will report on these science results and the status of production of high-level products to be provided from these observations.

Successful conservation of global waterbird populations depends on effective governance.

PubMed

Amano, Tatsuya; Székely, Tamás; Sandel, Brody; Nagy, Szabolcs; Mundkur, Taej; Langendoen, Tom; Blanco, Daniel; Soykan, Candan U; Sutherland, William J

2018-01-11

Understanding global patterns of biodiversity change is crucial for conservation research, policies and practices. However, for most ecosystems, the lack of systematically collected data at a global level limits our understanding of biodiversity changes and their local-scale drivers. Here we address this challenge by focusing on wetlands, which are among the most biodiverse and productive of any environments and which provide essential ecosystem services, but are also amongst the most seriously threatened ecosystems. Using birds as an indicator taxon of wetland biodiversity, we model time-series abundance data for 461 waterbird species at 25,769 survey sites across the globe. We show that the strongest predictor of changes in waterbird abundance, and of conservation efforts having beneficial effects, is the effective governance of a country. In areas in which governance is on average less effective, such as western and central Asia, sub-Saharan Africa and South America, waterbird declines are particularly pronounced; a higher protected area coverage of wetland environments facilitates waterbird increases, but only in countries with more effective governance. Our findings highlight that sociopolitical instability can lead to biodiversity loss and undermine the benefit of existing conservation efforts, such as the expansion of protected area coverage. Furthermore, data deficiencies in areas with less effective governance could lead to underestimations of the extent of the current biodiversity crisis.

Successful conservation of global waterbird populations depends on effective governance

NASA Astrophysics Data System (ADS)

Amano, Tatsuya; Székely, Tamás; Sandel, Brody; Nagy, Szabolcs; Mundkur, Taej; Langendoen, Tom; Blanco, Daniel; Soykan, Candan U.; Sutherland, William J.

2018-01-01

Understanding global patterns of biodiversity change is crucial for conservation research, policies and practices. However, for most ecosystems, the lack of systematically collected data at a global level limits our understanding of biodiversity changes and their local-scale drivers. Here we address this challenge by focusing on wetlands, which are among the most biodiverse and productive of any environments and which provide essential ecosystem services, but are also amongst the most seriously threatened ecosystems. Using birds as an indicator taxon of wetland biodiversity, we model time-series abundance data for 461 waterbird species at 25,769 survey sites across the globe. We show that the strongest predictor of changes in waterbird abundance, and of conservation efforts having beneficial effects, is the effective governance of a country. In areas in which governance is on average less effective, such as western and central Asia, sub-Saharan Africa and South America, waterbird declines are particularly pronounced; a higher protected area coverage of wetland environments facilitates waterbird increases, but only in countries with more effective governance. Our findings highlight that sociopolitical instability can lead to biodiversity loss and undermine the benefit of existing conservation efforts, such as the expansion of protected area coverage. Furthermore, data deficiencies in areas with less effective governance could lead to underestimations of the extent of the current biodiversity crisis.

The Global Geostationary Wildfire ABBA: Current Implementation and Future Plans

NASA Astrophysics Data System (ADS)

Prins, E.; Schmidt, C. C.; Hoffman, J.; Brunner, J.; Hyer, E. J.; Reid, J. S.

2012-12-01

The Wild Fire Automated Biomass Burning Algorithm (WF_ABBA), developed at the Cooperative Institute for Meteorological Satellite Studies (CIMSS), has a long legacy of operational near real-time wildfire detection and characterization in the Western Hemisphere. The first phase of the global geostationary WF_ABBA was made operational at NOAA NESDIS in 2009 and currently includes diurnal active fire monitoring from GOES-East, GOES-South America, GOES-West, Meteosat-9 and MTSAT-1R/-2. This allows for near global active fire monitoring with coverage of Europe, Africa, Southeast Asia and the Western Pacific utilizing distinct geostationary sensors and a consistent algorithm. Version 6.5.006 of the WF_ABBA was specifically designed to address the capabilities and limitations of diverse geostationary sensors and requests from the global fire monitoring and user community. This presentation will provide an overview of version 6.5.006 of the global WF_ABBA fire product including the new fire and opaque cloud mask and associated metadata. We will demonstrate the WF_ABBA showing examples from around the globe with a focus on the capabilities and plans for integrating new geostationary platforms with coverage of Eastern Europe and Asia (INSAT-3D, Korean COMS, Russian GOMS Elektro-L MSU-GS). We are also preparing for future fire monitoring in the Western Hemisphere, Europe, and Africa utilizing the next generation GOES-R Imager and Meteosat Third Generation Flexible Combined Imager (MTG - FCI). The goal is to create a globally consistent long-term fire product utilizing the capabilities of each of these unique operational systems and a common fire detection algorithm. On an international level, development of a global geostationary fire monitoring system is supported by the IGOS GOFC/GOLD Fire Implementation Team. This work also generally supports Committee on Earth Observation Satellites (CEOS) activities and the Group on Earth Observations (GEO).

Global control and regional elimination of measles, 2000-2012.

PubMed

Perry, Robert T; Gacic-Dobo, Marta; Dabbagh, Alya; Mulders, Mick N; Strebel, Peter M; Okwo-Bele, Jean-Marie; Rota, Paul A; Goodson, James L

2014-02-07

In 2010, the World Health Assembly established three milestones toward global measles eradication to be reached by 2015: 1) increase routine coverage with the first dose of measles-containing vaccine (MCV1) for children aged 1 year to ≥90% nationally and ≥80% in every district, 2) reduce and maintain annual measles incidence at <5 cases per million, and 3) reduce measles mortality by 95% from the 2000 estimate. After the adoption by member states of the South-East Asia Region (SEAR) of the goal of measles elimination by 2020, elimination goals have been set by member states of all six World Health Organization (WHO) regions, and reaching measles elimination in four WHO regions by 2015 is an objective of the Global Vaccine Action Plan (GVAP). This report updates the previous report for 2000-2011 and describes progress toward global control and regional elimination of measles during 2000-2012. During this period, increases in routine MCV coverage, plus supplementary immunization activities (SIAs) reaching 145 million children in 2012, led to a 77% decrease worldwide in reported measles annual incidence, from 146 to 33 per million population, and a 78% decline in estimated annual measles deaths, from 562,400 to 122,000. Compared with a scenario of no vaccination, an estimated 13.8 million deaths were prevented by measles vaccination during 2000-2012. Achieving the 2015 targets and elimination goals will require countries and their partners to raise the visibility of measles elimination and make substantial and sustained additional investments in strengthening health systems.

Who and where are the uncounted children? Inequalities in birth certificate coverage among children under five years in 94 countries using nationally representative household surveys.

PubMed

Bhatia, Amiya; Ferreira, Leonardo Zanini; Barros, Aluísio J D; Victora, Cesar Gomes

2017-08-18

Birth registration, and the possession of a birth certificate as proof of registration, has long been recognized as a fundamental human right. Data from a functioning civil registration and vital statistics (CRVS) system allows governments to benefit from accurate and universal data on birth and death rates. However, access to birth certificates remains challenging and unequal in many low and middle-income countries. This paper examines wealth, urban/rural and gender inequalities in birth certificate coverage. We analyzed nationally representative household surveys from 94 countries between 2000 and 2014 using Demographic Health Surveys and Multiple Indicator Cluster Surveys. Birth certificate coverage among children under five was examined at the national and regional level. Absolute measures of inequality were used to measure inequalities in birth certificate coverage by wealth quintile, urban/rural residence and sex of the child. Over four million children were included in the analysis. Birth certificate coverage was over 90% in 29 countries and below 50% in 36 countries, indicating that more than half the children under five surveyed in these countries did not have a birth certificate. Eastern & Southern Africa had the lowest average birth certificate coverage (26.9%) with important variability among countries. Significant wealth inequalities in birth certificate coverage were observed in 74 countries and in most UNICEF regions, and urban/rural inequalities were present in 60 countries. Differences in birth certificate coverage between girls and boys tended to be small. We show that wealth and urban/rural inequalities in birth certificate coverage persist in most low and middle income countries, including countries where national birth certificate coverage is between 60 and 80%. Weak CRVS systems, particularly in South Asia and Africa lead rural and poor children to be systematically excluded from the benefits tied to a birth certificate, and prevent these children from being counted in national health data. Greater funding and attention is needed to strengthen CRVS systems and equity analyses should inform such efforts, especially as data needs for the Sustainable Development Goals expand. Monitoring disaggregated data on birth certificate coverage is essential to reducing inequalities in who is counted and registered. Strengthening CRVS systems can enable a child's right to identity, improve health data and promote equity.

Leveraging Improvements in Precipitation Measuring from GPM Mission to Achieve Prediction Improvements in Climate, Weather and Hydrometeorology

NASA Technical Reports Server (NTRS)

Smith, Eric A.

2002-01-01

The main scientific goal of the GPM mission, currently planned for start in the 2007 time frame, is to investigate important scientific problems arising within the context of global and regional water cycles. These problems cut across a hierarchy of scales and include climate-water cycle interactions, techniques for improving weather and climate predictions, and better methods for combining observed precipitation with hydrometeorological prediction models for applications to hazardous flood-producing storms, seasonal flood/draught conditions, and fresh water resource assessments. The GPM mission will expand the scope of precipitation measurement through the use of a constellation of some 9 satellites, one of which will be an advanced TRMM-like "core" satellite carrying a dual-frequency Ku-Ka band precipitation radar and an advanced, multifrequency passive microwave radiometer with vertical-horizontal polarization discrimination. The other constellation members will include new dedicated satellites and co-existing Operational/research satellites carrying similar (but not identical) passive microwave radiometers. The goal of the constellation is to achieve approximately 3-hour sampling at any spot on the globe. The constellation's orbit architecture will consist of a mix of sun-synchronous and non-sun-synchronous satellites with the core satellite providing measurements of cloud-precipitation microphysical processes plus calibration-quality rainrate retrievals to be used with the other retrieval information to ensure bias-free constellation coverage. GPM is organized internationally, currently involving a partnership between NASA in the US and the National Space Development Agency in Japan. Additionally, the program is actively pursuing agreements with other international partners and domestic scientific agencies and institutions, as well as participation by individual scientists from academia, government, and the private sector to fulfill mission goals and to pave the way for what ultimately is expected to become an internationally-organized operational global precipitation observing system. Notably, the broad societal applications of GPM are reflected in the United Nation s identification of this mission as a foremost candidate for its Peaceful Uses of Space Program. In this presentation, an overview of the GPM mission design will be presented, followed by an explanation of its scientific agenda as an outgrowth of making improvements in rain retrieval accuracy, microphysics dexterity, sampling frequency, and global coverage. All of these improvements offer new means to observe variability in precipitation and water cycle fluxes and to achieve improved predictability of weather, climate, and hydrometeorology. Specifically, the scientific agenda of GPM has been designed to leverage the measurement improvements to improve prognostic model performance, particularly quantitative precipitation forecasting and its linked phenomena at short, intermediate, and extended time scales. The talk will address how GPM measurements will enable better detection of accelerations and decelerations in regional and global water cycle processes and their relationship to climate variability, better impacts of precipitation data assimilation on numerical weather prediction and global climate reanalysis, and better performance from basin scale hydrometeorological models for short and long term flood-drought forecasting and seasonal fresh water resource assessment. Improved hydrometeorological forecasting will be possible by using continuous global precipitation observations to obtain better closure in water budgets and to generate more realistic forcing of the models themselves to achieve more accurate estimates of interception, infiltration, evaporation/transpiration fluxes, storage, and runoff.

Water Cycling &the GPM Mission

NASA Astrophysics Data System (ADS)

Smith, E. A.

2003-04-01

The GPM mission is currently planned for start in the late'07 - early'08 time frame. Its main scientific goal is to help answer pressing scientific problems arising within the context of global and regional water cycles. These problems cut across a hierarchy of scales and include climate-water cycle interactions, techniques for improving weather and climate predictions, and better methods for combining observed precipitation with hydrometeorological prediction models for applications to hazardous flood-producing storms, seasonal flood/draught conditions, and fresh water resource assessments. The GPM mission will expand the scope of precipitation measurement through the use of a constellation of some 9 satellites, one of which will be an advanced TRMM-like "core" satellite carrying a dual-frequency Ku-Ka band precipitation radar and an advanced, multifrequency passive microwave radiometer with vertical-horizontal polarization discrimination. The other constellation members will include new dedicated satellites and co-existing operational/research satellites carrying similar (but not identical) passive microwave radiometers. The goal of the constellation is to achieve 3-hour sampling at any spot on the globe - continuously. The constellation's orbit architecture will consist of a mix of sun-synchronous and non-sun-synchronous satellites with the "core" satellite providing measurements of cloud-precipitation microphysical processes plus calibration-quality rainrates to be used with the other retrieval information to ensure bias-free constellation coverage. GPM is organized internationally, involving existing, pending, projected, and under-study partnerships which will link NASA and NOAA in the US, NASDA in Japan, ESA in Europe, ISRO in India, CNES in France, and possibly ASI in Italy, KARI in South Korea, CSA in Canada, and AEB in Brazil. Additionally, the program is actively pursuing agreements with other international collaborators and domestic scientific agencies and institutions, as well as participation by individual scientists from academia, government, and the private sector to fulfill mission goals and to pave the way for what ultimately is expected to become an internationally-organized operational global precipitation observing system. Notably, the broad societal applications of GPM are reflected in the United Nation's identification of this mission as a foremost candidate for its Peaceful Uses of Space Program. An overview of the GPM mission design is given, followed by an explanation of its scientific agenda as an outgrowth of making improvements in rain retrieval accuracy, microphysics dexterity, sampling frequency, and global coverage. All of these improvements offer new means to observe variability in precipitation and water cycle fluxes, to improve water budget closure at regional and global scales, and to leverage these improvements in achieving improved predictability of weather, climate, and hydrometeorology. Specifically, the scientific agenda of GPM has been designed to leverage the measurement improvements to improve prognostic model performance, particularly quantitative precipitation forecasting and its linked phenomena at short, intermediate, and extended time scales. The talk addresses how GPM measurements will enable more accurate satellite-based calculations of the water cycle relative to where things stand today (two examples will be provided), and how such measurements can be used to evaluate accelerations and decelerations in regional and global water cycle processes and thus improve our understanding of water-driven climatic shifts. These improvements become possible by using more accurate, more microphysically-centric, more frequent, and fully global precipitation observations to achieve better water budget closure and to provide more realistic forcing and assessment of prediction models.

Anticipated Improvements in Precipitation Physics and Understanding of Water Cycle from GPM Mission

NASA Technical Reports Server (NTRS)

Smith, Eric A.

2003-01-01

The GPM mission is currently planned for start in the late-2007 to early-2008 time frame. Its main scientific goal is to help answer pressing scientific problems arising within the context of global and regional water cycles. These problems cut across a hierarchy of scales and include climate-water cycle interactions, techniques for improving weather and climate predictions, and better methods for combining observed precipitation with hydrometeorological prediction models for applications to hazardous flood-producing storms, seasonal flood/draught conditions, and fresh water resource assessments. The GPM mission will expand the scope of precipitation measurement through the use of a constellation of some 9 satellites, one of which will be an advanced TRMM-like core satellite carrying a dual-frequency Ku-Ka band precipitation radar and an advanced, multifrequency passive microwave radiometer with vertical-horizontal polarization discrimination. The other constellation members will include new dedicated satellites and co-existing operational/research satellites carrying similar (but not identical) passive microwave radiometers. The goal of the constellation is to achieve approximately 3-hour sampling at any spot on the globe -- continuously. The constellation s orbit architecture will consist of a mix of sun-synchronous and non-sun-synchronous satellites with the core satellite providing measurements of cloud-precipitation microphysical processes plus calibration-quality rainrate retrievals to be used with the other retrieval information to ensure bias-free constellation coverage. GPM is organized internationally, involving existing, pending, projected, and under-study partnerships which will link NASA and NOAA in the US, NASDA in Japan, ESA in Europe, ISRO in India, CNES in France, and possibly AS1 in Italy, KARI in South Korea, CSA in Canada, and AEB in Brazil. Additionally, the program is actively pursuing agreements with other international collaborators and domestic scientific agencies and institutions, as well as participation by individual scientists from academia, government, and the private sector to fulfill mission goals and to pave the way for what is expected to become an internationally-organized operational global precipitation observing system. Notably, the broad societal applications of GPM are reflected in the United Nation s identification of GPM as a foremost candidate for its Peaceful Uses of Space Program. An overview of the GPM mission design is given, followed by an explanation of its scientific agenda as an outgrowth of making improvements in rain retrieval accuracy, microphysics dexterity, sampling frequency, and global coverage. All of these improvements offer new means to observe variability in precipitation and water cycle fluxes and to achieve improved predictability of weather, climate, and hydrometeorology. Specifically, the scientific agenda of GPM has been designed to leverage the measurement improvements to improve prognostic model performance, particularly quantitative precipitation forecasting and its linked phenomena at short, intermediate, and extended time scales. The talk addresses how GPM measurements will enable better detection of accelerations and decelerations in regional and global water cycle processes and their relationship to climate variability, better impacts of precipitation data assimilation on numerical weather prediction and global climate reanalysis, and better performance from basin scale hydrometeorological models for short and long term flood-drought forecasting and seasonal fresh water resource assessment. These improvements become possible by using more accurate, more microphysically-centric, more frequent, and fully global precipitation observations to achieve better water budget closure and to provide more realistic forcing and assessment of prediction models.

BingEO: Enable Distributed Earth Observation Data for Environmental Research

NASA Astrophysics Data System (ADS)

Wu, H.; Yang, C.; Xu, Y.

2010-12-01

Our planet is facing great environmental challenges including global climate change, environmental vulnerability, extreme poverty, and a shortage of clean cheap energy. To address these problems, scientists are developing various models to analysis, forecast, simulate various geospatial phenomena to support critical decision making. These models not only challenge our computing technology, but also challenge us to feed huge demands of earth observation data. Through various policies and programs, open and free sharing of earth observation data are advocated in earth science. Currently, thousands of data sources are freely available online through open standards such as Web Map Service (WMS), Web Feature Service (WFS) and Web Coverage Service (WCS). Seamless sharing and access to these resources call for a spatial Cyberinfrastructure (CI) to enable the use of spatial data for the advancement of related applied sciences including environmental research. Based on Microsoft Bing Search Engine and Bing Map, a seamlessly integrated and visual tool is under development to bridge the gap between researchers/educators and earth observation data providers. With this tool, earth science researchers/educators can easily and visually find the best data sets for their research and education. The tool includes a registry and its related supporting module at server-side and an integrated portal as its client. The proposed portal, Bing Earth Observation (BingEO), is based on Bing Search and Bing Map to: 1) Use Bing Search to discover Web Map Services (WMS) resources available over the internet; 2) Develop and maintain a registry to manage all the available WMS resources and constantly monitor their service quality; 3) Allow users to manually register data services; 4) Provide a Bing Maps-based Web application to visualize the data on a high-quality and easy-to-manipulate map platform and enable users to select the best data layers online. Given the amount of observation data accumulated already and still growing, BingEO will allow these resources to be utilized more widely, intensively, efficiently and economically in earth science applications.

THE POTENTIAL APPLICATION OF FIRESAT DATA TO ASSESSMENT OF HUMAN EXPOSURES TO WILDFIRE EMISSIONS

EPA Science Inventory

FireSat is a proposed NASA mission that will obtain global coverage of the occurrence of wildfires. The specifications for FireSat are described in detail by Levine et al., (1991). Because of limitations of instruments (designed for other purposes) in existing satellites, new in...

Global Magellan-image map of Venus at full resolution

NASA Technical Reports Server (NTRS)

Kirk, R. L.; Edwards, K. B.; Morgan, H. F.; Soderblom, L. A.; Stoewe, T. L.

1993-01-01

During its first 243-day mapping cycle, the Magellan spacecraft succeeded in imaging 84 percent of the surface of Venus at resolutions on the order of 100 meters; subsequent cycles have increased the total coverage to over 97 percent and provided redundant coverage of much of the planet with differing viewing geometries. Unfortunately, this full-resolution global dataset is in the form of thousands of individual orbit tracks (F-BIDR's) whose length-to-width ratio of nearly 1000:1 makes them minimally useful unless mosaicked. The Magellan project produced full-resolution mosaics (F-MIDR's) only for selected regions on the planet, whereas a global set of mosaics was made only at threefold degraded resolution (C1-MIDR's). Furthermore, although the F-MIDR's, which are approximately equidimensional, are much better suited for scientific interpretation than the F-BIDR's, they are still an unwieldy dataset: over 1500 quadrangles, each showing a region only about 600 km on a side, would be required to cover the entire planet. The USGS has therefore undertaken to produce and distribute a global, full resolution set of mosaics of the Magellan image data in a format that will be efficient for both hardcopy and digital use. The initial motivation was that it would provide an efficient means of verifying the integrity of the F-BIDR's to be archived on computer-compatible tape at the USGS Flagstaff facility. However, the resulting product, known as the FMAP, should also serve as an important resource for future scientific interpretation. It will offer several advantages beyond global coverage at full resolution. The first, alluded to above, is its division of the planet's surface to minimize the number of quadrangles and maximize their area, subject to the limits on the number of pixels imposed by state-of-the-art digital recording media and hardcopy output devices. The second, the use of improved 'cosmetic' processing techniques, will greatly reduce tonal discontinuities between component F-BIDR's in the FMAP compared to the standard Magellan mosaic products. Finally, wherever possible, the FMAP will incorporate data that were unavailable (e.g., because of processing delays) when the standard MIDR products were created, as well as data that were reprocessed to improve their radiometric or geometric quality.

Global Color Views of Mars

NASA Technical Reports Server (NTRS)

1997-01-01

About 1000 Viking Orbiter red- and violet-filter images have been processed to provide global color coverage of Mars at a scale of 1 km/pixel. Individual image frames acquired during a single spacecraft revolution were first processed through radiometric calibration, cosmetic cleanup, geometric control, reprojection, and mosaicing. We have produced a total of 57 'single-rev' mosaics. All of the mosaics are geometrically tied to the Mars Digital Image Mosaic, a black-and-white base map with a scale of 231 m/pixel. We selected a subset of single-rev mosaics that provide the best global coverage (least atmospheric obscuration and seasonal frost); photometric normalization was applied to remove atmospheric effects and normalize the variations in illumination and viewing angles. Finally, these normalized mosaics were combined into global mosaics. Global coverage is about 98% complete in the red-filter mosaic and 95% complete in the violet-filter mosaic. Gaps were filled by interpolation. A green-filter image was synthesized from an average of the red and violet filter data to complete a 3-color set. The Viking Orbiters acquired actual green-filter images for only about half of the Martian surface. The final mosaic has been reprojected into several map projections. The orthographic view shown here is centered at 20 degrees latitude and 60 degrees longitude. The orthographic view is most like the view seen by a distant observer looking through a telescope. The color balance selected for these images was designed to be close to natural color for the bright reddish regions such as Tharsis and Arabia, but the data have been 'stretched' such that the relatively dark regions appear darker and less reddish that their natural appearance. This stretching allows us to better see the color and brightness variations on Mars, which are related to the composition or physical structure of the surface materials, which include volcanic lava flows, wind- and water-deposited sedimentary rocks, and (at the poles) ice caps. The north polar cap is visible in this projection at the top of the image, the great equatorial canyon system (Valles Marineris) below center, and four huge Tharsis volcanoes (and several smaller ones) at left. Also note heavy impact cratering of the highlands (bottom and right portions of this mosaic) and the younger, less heavily cratered terrains elsewhere.

Exploring the Moon at High-Resolution: First Results From the Lunar Reconnaissance Orbiter Camera (LROC)

NASA Astrophysics Data System (ADS)

Robinson, Mark; Hiesinger, Harald; McEwen, Alfred; Jolliff, Brad; Thomas, Peter C.; Turtle, Elizabeth; Eliason, Eric; Malin, Mike; Ravine, A.; Bowman-Cisneros, Ernest

The Lunar Reconnaissance Orbiter (LRO) spacecraft was launched on an Atlas V 401 rocket from the Cape Canaveral Air Force Station Launch Complex 41 on June 18, 2009. After spending four days in Earth-Moon transit, the spacecraft entered a three month commissioning phase in an elliptical 30×200 km orbit. On September 15, 2009, LRO began its planned one-year nominal mapping mission in a quasi-circular 50 km orbit. A multi-year extended mission in a fixed 30×200 km orbit is optional. The Lunar Reconnaissance Orbiter Camera (LROC) consists of a Wide Angle Camera (WAC) and two Narrow Angle Cameras (NACs). The WAC is a 7-color push-frame camera, which images the Moon at 100 and 400 m/pixel in the visible and UV, respectively, while the two NACs are monochrome narrow-angle linescan imagers with 0.5 m/pixel spatial resolution. LROC was specifically designed to address two of the primary LRO mission requirements and six other key science objectives, including 1) assessment of meter-and smaller-scale features in order to select safe sites for potential lunar landings near polar resources and elsewhere on the Moon; 2) acquire multi-temporal synoptic 100 m/pixel images of the poles during every orbit to unambiguously identify regions of permanent shadow and permanent or near permanent illumination; 3) meter-scale mapping of regions with permanent or near-permanent illumination of polar massifs; 4) repeat observations of potential landing sites and other regions to derive high resolution topography; 5) global multispectral observations in seven wavelengths to characterize lunar resources, particularly ilmenite; 6) a global 100-m/pixel basemap with incidence angles (60° -80° ) favorable for morphological interpretations; 7) sub-meter imaging of a variety of geologic units to characterize their physical properties, the variability of the regolith, and other key science questions; 8) meter-scale coverage overlapping with Apollo-era panoramic images (1-2 m/pixel) to document the number of small impacts since 1971-1972. LROC allows us to determine the recent impact rate of bolides in the size range of 0.5 to 10 meters, which is currently not well known. Determining the impact rate at these sizes enables engineering remediation measures for future surface operations and interplanetary travel. The WAC has imaged nearly the entire Moon in seven wavelengths. A preliminary global WAC stereo-based topographic model is in preparation [1] and global color processing is underway [2]. As the mission progresses repeat global coverage will be obtained as lighting conditions change providing a robust photometric dataset. The NACs are revealing a wealth of morpho-logic features at the meter scale providing the engineering and science constraints needed to support future lunar exploration. All of the Apollo landing sites have been imaged, as well as the majority of robotic landing and impact sites. Through the use of off-nadir slews a collection of stereo pairs is being acquired that enable 5-m scale topographic mapping [3-7]. Impact mor-phologies (terraces, impact melt, rays, etc) are preserved in exquisite detail at all Copernican craters and are enabling new studies of impact mechanics and crater size-frequency distribution measurements [8-12]. Other topical studies including, for example, lunar pyroclastics, domes, and tectonics are underway [e.g., 10-17]. The first PDS data release of LROC data will be in March 2010, and will include all images from the commissioning phase and the first 3 months of the mapping phase. [1] Scholten et al. (2010) 41st LPSC, #2111; [2] Denevi et al. (2010a) 41st LPSC, #2263; [3] Beyer et al. (2010) 41st LPSC, #2678; [4] Archinal et al. (2010) 41st LPSC, #2609; [5] Mattson et al. (2010) 41st LPSC, #1871; [6] Tran et al. (2010) 41st LPSC, #2515; [7] Oberst et al. (2010) 41st LPSC, #2051; [8] Bray et al. (2010) 41st LPSC, #2371; [9] Denevi et al. (2010b) 41st LPSC, #2582; [10] Hiesinger et al. (2010a) 41st LPSC, #2278; [11] Hiesinger et al. (2010b) 41st LPSC, #2304; [12] van der Bogert et al. (2010) 41st LPSC, #2165; [13] Plescia et al. (2010) 41st LPSC, #2160; [14] Lawrence et al. (2010) 41st LPSC, #1906; [15] Gaddis et al. (2010) 41st LPSC, #2059; [16] Watters et al. (2010) 41st LPSC, #1863; [17] Garry et al. (2010) 41st LPSC, #2278.

Bridging the climate-induced water gap in the twenty-first century: adaptation support based on water supply, demand, adaptation and financing.

NASA Astrophysics Data System (ADS)

Straatsma, Menno; Droogers, Peter; Brandsma, Jaïrus; Buytaert, Wouter; Karssenberg, Derek; Van Beek, Rens; Wada, Yoshihide; Sutanudjaja, Edwin; Vitolo, Claudia; Schmitz, Oliver; Meijer, Karen; Van Aalst, Maaike; Bierkens, Marc

2014-05-01

Water scarcity affects large parts of the world. Over the course of the twenty-first century, water demand is likely to increase due to population growth and associated food production, and increased economic activity, while water supply is projected to decrease in many regions due to climate change. Despite recent studies that analyze the effect of climate change on water scarcity, e.g. using climate projections under representative concentration pathways (RCP) of the fifth assessment report of the IPCC (AR5), decision support for closing the water gap between now and 2100 does not exist at a meaningful scale and with a global coverage. In this study, we aimed (i) to assess the joint impact of climatic and socio-economic change on water scarcity, (ii) to integrate impact and potential adaptation in one workflow, (iii) to prioritize adaptation options to counteract water scarcity based on their financial, regional socio-economic and environmental implications, and (iv) to deliver all this information in an integrated user-friendly web-based service. To enable the combination of global coverage with local relevance, we aggregated all results for 1604 water provinces (food producing units) delineated in this study, which is five times smaller than previous food producing units. Water supply was computed using the PCR-GLOBWB hydrological and water resources model, parameterized at 5 arcminutes for the whole globe, excluding Antarctica and Greenland. We ran PCR-GLOBWB with a daily forcing derived from five different GCM models from the CMIP5 (GFDL-ESM2M, Hadgem2-ES, IPSL-CMA5-LR, MIROC-ESM-CHEM, NorESM1-M) that were bias corrected using observation-based WATCH data between 1960-1999. For each of the models all four RCPs (RCP 2.6, 4.5, 6.0, and 8.5) were run, producing the ensemble of 20 future projections. The blue water supply was aggregated per month and per water province. Industrial, domestic and irrigation water demands were computed for a limited number of realistic combinations of a shared socio-economic pathways (SSPs) and RCPs. Our Water And Climate Adaptation Model (WatCAM) was used to compute the water gap based on reservoir capacity, water supply, and water demand. WatCam is based on the existing ModSim (Labadie, 2010) water allocation model, and facilitated the evaluation of nine technological and infrastructural adaptation measures to assess the investments needed to bridge the future water gap. Regional environmental and socio-economic effects of these investments, such as environmental flows or downstream effects, were evaluated. A scheme was developed to evaluate the strategies on robustness and flexibility under climate change and scenario uncertainty, and each measure was linked to possibilities for investment and financing mechanisms. The WatCAM is available as a web modeling service from www.water2invest.com, and enables user specified adaptation measures and the creation of an ensemble of water gap forecasts.

Evaluation of ISCCP multisatellite radiance calibration for geostationary imager visible channels using the moon

USGS Publications Warehouse

Stone, Thomas C.; William B. Rossow,; Joseph Ferrier,; Laura M. Hinkelman,

2013-01-01

Since 1983, the International Satellite Cloud Climatology Project (ISCCP) has collected Earth radiance data from the succession of geostationary and polar-orbiting meteorological satellites operated by weather agencies worldwide. Meeting the ISCCP goals of global coverage and decade-length time scales requires consistent and stable calibration of the participating satellites. For the geostationary imager visible channels, ISCCP calibration provides regular periodic updates from regressions of radiances measured from coincident and collocated observations taken by Advanced Very High Resolution Radiometer instruments. As an independent check of the temporal stability and intersatellite consistency of ISCCP calibrations, we have applied lunar calibration techniques to geostationary imager visible channels using images of the Moon found in the ISCCP data archive. Lunar calibration enables using the reflected light from the Moon as a stable and consistent radiometric reference. Although the technique has general applicability, limitations of the archived image data have restricted the current study to Geostationary Operational Environmental Satellite and Geostationary Meteorological Satellite series. The results of this lunar analysis confirm that ISCCP calibration exhibits negligible temporal trends in sensor response but have revealed apparent relative biases between the satellites at various levels. However, these biases amount to differences of only a few percent in measured absolute reflectances. Since the lunar analysis examines only the lower end of the radiance range, the results suggest that the ISCCP calibration regression approach does not precisely determine the intercept or the zero-radiance response level. We discuss the impact of these findings on the development of consistent calibration for multisatellite global data sets.

Arctic shipping emissions inventories and future scenarios

NASA Astrophysics Data System (ADS)

Corbett, J. J.; Lack, D. A.; Winebrake, J. J.; Harder, S.; Silberman, J. A.; Gold, M.

2010-04-01

The Arctic is a sensitive region in terms of climate change and a rich natural resource for global economic activity. Arctic shipping is an important contributor to the region's anthropogenic air emissions, including black carbon - a short-lived climate forcing pollutant especially effective in accelerating the melting of ice and snow. These emissions are projected to increase as declining sea ice coverage due to climate change allows for increased shipping activity in the Arctic. To understand the impacts of these increased emissions, scientists and modelers require high-resolution, geospatial emissions inventories that can be used for regional assessment modeling. This paper presents 5 km×5 km Arctic emissions inventories of important greenhouse gases, black carbon and other pollutants under existing and future (2050) scenarios that account for growth of shipping in the region, potential diversion traffic through emerging routes, and possible emissions control measures. Short-lived forcing of ~4.5 gigagrams of black carbon from Arctic shipping may increase climate forcing; a first-order calculation of global warming potential due to 2030 emissions in the high-growth scenario suggests that short-lived forcing of ~4.5 gigagrams of black carbon from Arctic shipping may increase climate forcing due to Arctic ships by at least 17% compared to warming from these vessels' CO2 emissions (~42 000 gigagrams). The paper also presents maximum feasible reduction scenarios for black carbon in particular. These emissions reduction scenarios will enable scientists and policymakers to evaluate the efficacy and benefits of technological controls for black carbon, and other pollutants from ships.

Local gravity disturbance estimation from multiple-high-single-low satellite-to-satellite tracking

NASA Technical Reports Server (NTRS)

Jekeli, Christopher

1989-01-01

The idea of satellite-to-satellite tracking in the high-low mode has received renewed attention in light of the uncertain future of NASA's proposed low-low mission, Geopotential Research Mission (GRM). The principal disadvantage with a high-low system is the increased time interval required to obtain global coverage since the intersatellite visibility is often obscured by Earth. The U.S. Air Force has begun to investigate high-low satellite-to-satellite tracking between the Global Positioning System (GPS) of satellites (high component) and NASA's Space Transportation System (STS), the shuttle (low component). Because the GPS satellites form, or will form, a constellation enabling continuous three-dimensional tracking of a low-altitude orbiter, there will be no data gaps due to lack of intervisibility. Furthermore, all three components of the gravitation vector are estimable at altitude, a given grid of which gives a stronger estimate of gravity on Earth's surface than a similar grid of line-of-sight gravitation components. The proposed Air Force mission is STAGE (Shuttle-GPS Tracking for Anomalous Gravitation Estimation) and is designed for local gravity field determinations since the shuttle will likely not achieve polar orbits. The motivation for STAGE was the feasibility to obtain reasonable accuracies with absolutely minimal cost. Instead of simulating drag-free orbits, STAGE uses direct measurements of the nongravitational forces obtained by an inertial package onboard the shuttle. The sort of accuracies that would be achievable from STAGE vis-a-vis other satellite tracking missions such as GRM and European Space Agency's POPSAT-GRM are analyzed.

Investing in life saving vaccines to guarantee life of future generations in Africa.

PubMed

Mihigo, R M; Okeibunor, J C; O'Malley, H; Masresha, B; Mkanda, P; Zawaira, F

2016-11-21

The World Health Organization's Regional Offices for Africa and for the Eastern Mediterranean in conjunction with the African Union and the Government of Ethiopia hosted a ministerial conference on immunization in Africa from 24 to 25 February 2016 in Addis Ababa, Ethiopia under the theme "towards universal immunization coverage as a cornerstone for health and development in Africa". The conference brought together African leaders - including health and finance ministers, and parliamentarians thus creating a powerful platform for governments to demonstrate their commitment to advancing universal access to immunization on the continent in line with the Global Vaccine Action Plan. The event also brought together advocates, technical experts, policymakers, partner agencies, donors and journalists to examine how best to drive forward immunization across Africa, ensuring every child has access to the vaccines they need. Key points highlighted throughout conference were: universal access to immunization is at the forefront of enabling Africa to reach its full potential - by improving health, driving economic growth and empowering future generations; it is one of the most cost-effective solutions in global health, with clear benefits for health and development; and immunization brings economic benefits too, reducing health care costs and increasing productivity. At the close of the conference, 46 African countries signed a historic ministerial declaration on "Universal Access to Immunization as a Cornerstone for Health and Development in Africa" signaling fierce determination among African leaders to secure the health and prosperity of their societies through immunization. Copyright © 2016 World Health Organization Regional Office for Africa. Published by Elsevier Ltd.. All rights reserved.

Soup to Tree: The Phylogeny of Beetles Inferred by Mitochondrial Metagenomics of a Bornean Rainforest Sample

PubMed Central

Crampton-Platt, Alex; Timmermans, Martijn J.T.N.; Gimmel, Matthew L.; Kutty, Sujatha Narayanan; Cockerill, Timothy D.; Vun Khen, Chey; Vogler, Alfried P.

2015-01-01

In spite of the growth of molecular ecology, systematics and next-generation sequencing, the discovery and analysis of diversity is not currently integrated with building the tree-of-life. Tropical arthropod ecologists are well placed to accelerate this process if all specimens obtained through mass-trapping, many of which will be new species, could be incorporated routinely into phylogeny reconstruction. Here we test a shotgun sequencing approach, whereby mitochondrial genomes are assembled from complex ecological mixtures through mitochondrial metagenomics, and demonstrate how the approach overcomes many of the taxonomic impediments to the study of biodiversity. DNA from approximately 500 beetle specimens, originating from a single rainforest canopy fogging sample from Borneo, was pooled and shotgun sequenced, followed by de novo assembly of complete and partial mitogenomes for 175 species. The phylogenetic tree obtained from this local sample was highly similar to that from existing mitogenomes selected for global coverage of major lineages of Coleoptera. When all sequences were combined only minor topological changes were induced against this reference set, indicating an increasingly stable estimate of coleopteran phylogeny, while the ecological sample expanded the tip-level representation of several lineages. Robust trees generated from ecological samples now enable an evolutionary framework for ecology. Meanwhile, the inclusion of uncharacterized samples in the tree-of-life rapidly expands taxon and biogeographic representation of lineages without morphological identification. Mitogenomes from shotgun sequencing of unsorted environmental samples and their associated metadata, placed robustly into the phylogenetic tree, constitute novel DNA “superbarcodes” for testing hypotheses regarding global patterns of diversity. PMID:25957318

SENTINEL-2 Global Reference Image Validation and Application to Multitemporal Performances and High Latitude Digital Surface Model

NASA Astrophysics Data System (ADS)

Gaudel, A.; Languille, F.; Delvit, J. M.; Michel, J.; Cournet, M.; Poulain, V.; Youssefi, D.

2017-05-01

In the frame of the Copernicus program of the European Commission, Sentinel-2 is a constellation of 2 satellites with a revisit time of 5 days in order to have temporal images stacks and a global coverage over terrestrial surfaces. Satellite 2A was launched in June 2015, and satellite 2B will be launched in March 2017. In cooperation with the European Space Agency (ESA), the French space agency (CNES) is in charge of the image quality of the project, and so ensures the CAL/VAL commissioning phase during the months following the launch. This cooperation is also extended to routine phase as CNES supports European Space Research Institute (ESRIN) and the Sentinel-2 Mission performance Centre (MPC) for validation in geometric and radiometric image quality aspects, and in Sentinel-2 GRI geolocation performance assessment whose results will be presented in this paper. The GRI is a set of S2A images at 10m resolution covering the whole world with a good and consistent geolocation. This ground reference enables accurate multi-temporal registration of refined Sentinel-2 products. While not primarily intended for the generation of DSM, Sentinel-2 swaths overlap between orbits would also allow for the generation of a complete DSM of land and ices over 60° of northern latitudes (expected accuracy: few S2 pixels in altimetry). This DSM would benefit from the very frequent revisit times of Sentinel-2, to monitor ice or snow level in area of frequent changes, or to increase measurement accuracy in areas of little changes.

Multi-Parameter GEOSCOPE Land Stations and Ocean Bottom Observatories

NASA Astrophysics Data System (ADS)

Stutzmann, E.; Roult, G.; Montagner, J.; Karczewski, J.; Geoscope Group,.

2002-12-01

Since the mid-eighties, the number of high quality broadband stations installed over the world has increased in a spectacular way and these stations cover now most of the emerged lands, with a higher concentration in the northern hemisphere between the latitudes 0 and 60N. The GEOSCOPE program has been the first global network of 3-component broadband seismic stations and has contributed to the elaboration of the FDSN. The 25 broadband GEOSCOPE stations fulfill the FDSN criteria, the data are stored in data-centers at the IPGP and IRIS DMC and are accessible through the netdc procedure (email to netdc@ipgp.jussieu.fr) or via the web. GEOSCOPE data have contributed to the major progresses of our knowledge of the earth interior. The earthquake CMT are now determined in a routine manner and the temporal history of the seismic source is accessible for the largest earthquakes. The geographical distribution of GEOSCOPE stations, specially in the southern hemisphere, has also played an important role in improving the resolution of global tomographic models. Recent P-wave models give high resolution images of subducted slabs whereas recent S-wave models have enable to discover the two super-swells. The evolution of the GEOSCOPE program is now focused on the installation of multi-parameter stations including 3-component broadband seismic sensors, pressure gauge, thermometer and GPS receivers. These stations will enable to decrease the seismic noise, and -among others- to better characterize the background free oscillations of the earth. The seismic station earth coverage is limited by the presence of oceans and the next step is the installation of ocean bottom broadband stations. For this purpose, in 1992, a first temporary station sismobs/OFM has been working for 2 weeks, along the mid atlantic ridge. In 1997, an international multi-parameter station, MOISE has been operating during 3 months in the Monterey Bay. The further step is the installation of the station NERO in a ODP hole along the Ninety East Ridge in collaboration with IFREMER and JAMSTEC. The location of this station has been decided by the ION program and the station will be operating for at least 2 years.

Automated Agricultural Field Extraction from Multi-temporal Web Enabled Landsat Data

NASA Astrophysics Data System (ADS)

Yan, L.; Roy, D. P.

2012-12-01

Agriculture has caused significant anthropogenic surface change. In many regions agricultural field sizes may be increasing to maximize yields and reduce costs resulting in decreased landscape spatial complexity and increased homogenization of land uses with potential for significant biogeochemical and ecological effects. To date, studies of the incidence, drivers and impacts of changing field sizes have not been undertaken over large areas because of computational constraints and because consistently processed appropriate resolution data have not been available or affordable. The Landsat series of satellites provides near-global coverage, long term, and appropriate spatial resolution (30m) satellite data to document changing field sizes. The recent free availability of all the Landsat data in the U.S. Landsat archive now provides the opportunity to study field size changes in a global and consistent way. Commercial software can be used to extract fields from Landsat data but are inappropriate for large area application because they require considerable human interaction. This paper presents research to develop and validate an automated computational Geographic Object Based Image Analysis methodology to extract agricultural fields and derive field sizes from Web Enabled Landsat Data (WELD) (http://weld.cr.usgs.gov/). WELD weekly products (30m reflectance and brightness temperature) are classified into Satellite Image Automatic Mapper™ (SIAM™) spectral categories and an edge intensity map and a map of the probability of each pixel being agricultural are derived from five years of 52 weeks of WELD and corresponding SIAM™ data. These data are fused to derive candidate agriculture field segments using a variational region-based geometric active contour model. Geometry-based algorithms are used to decompose connected segments belonging to multiple fields into coherent isolated field objects with a divide and conquer strategy to detect and merge partial circle segments. Results are presented for several 5000 x 5000 30m pixel WELD tiles encompassing rectangular and circular (pivot irrigation) fields in Texas and California and the results are validated qualitatively by comparison with high spatial resolution images obtained from the National Geospatial-Intelligence Agency (NGA) Commercial Archive. Implications and recommendations for algorithm refinement and application to decadal conterminous United States WELD data are discussed.

Indicators for Universal Health Coverage: can Kenya comply with the proposed post-2015 monitoring recommendations?

PubMed

Obare, Valerie; Brolan, Claire E; Hill, Peter S

2014-12-20

Universal Health Coverage (UHC), referring to access to healthcare without financial burden, has received renewed attention in global health spheres. UHC is a potential goal in the post-2015 development agenda. Monitoring of progress towards achieving UHC is thus critical at both country and global level, and a monitoring framework for UHC was proposed by a joint WHO/World Bank discussion paper in December 2013. The aim of this study was to determine the feasibility of the framework proposed by WHO/World Bank for global UHC monitoring framework in Kenya. The study utilised three documents--the joint WHO/World Bank UHC monitoring framework and its update, and the Bellagio meeting report sponsored by WHO and the Rockefeller Foundation--to conduct the research. These documents informed the list of potential indicators that were used to determine the feasibility of the framework. A purposive literature search was undertaken to identify key government policy documents and relevant scholarly articles. A desk review of the literature was undertaken to answer the research objectives of this study. Kenya has yet to establish an official policy on UHC that provides a clear mandate on the goals, targets and monitoring and evaluation of performance. However, a significant majority of Kenyans continue to have limited access to health services as well as limited financial risk protection. The country has the capacity to reasonably report on five out of the seven proposed UHC indicators. However, there was very limited capacity to report on the two service coverage indicators for the chronic condition and injuries (CCIs) interventions. Out of the potential tracer indicators (n = 27) for aggregate CCI-related measures, four tracer indicators were available. Moreover the country experiences some wider challenges that may impact on the implementation and feasibility of the WHO/World Bank framework. The proposed global framework for monitoring UHC will only be feasible in Kenya if systemic challenges are addressed. While the infrastructure for reporting the MDG related indicators is in place, Kenya will require continued international investment to extend its capacity to meet the data requirements of the proposed UHC monitoring framework, particularly for the CCI-related indicators.

Rapid Technology Assessment via Unified Deployment of Global Optical and Virtual Diagnostics

NASA Technical Reports Server (NTRS)

Jordan, Jeffrey D.; Watkins, A. Neal; Fleming, Gary A.; Leighty, Bradley D.; Schwartz, Richard J.; Ingram, JoAnne L.; Grinstead, Keith D., Jr.; Oglesby, Donald M.; Tyler, Charles

2003-01-01

This paper discusses recent developments in rapid technology assessment resulting from an active collaboration between researchers at the Air Force Research Laboratory (AFRL) at Wright Patterson Air Force Base (WPAFB) and the NASA Langley Research Center (LaRC). This program targets the unified development and deployment of global measurement technologies coupled with a virtual diagnostic interface to enable the comparative evaluation of experimental and computational results. Continuing efforts focus on the development of seamless data translation methods to enable integration of data sets of disparate file format in a common platform. Results from a successful low-speed wind tunnel test at WPAFB in which global surface pressure distributions were acquired simultaneously with model deformation and geometry measurements are discussed and comparatively evaluated with numerical simulations. Intensity- and lifetime-based pressure-sensitive paint (PSP) and projection moire interferometry (PMI) results are presented within the context of rapid technology assessment to enable simulation-based R&D.

Lunar geodesy and cartography: a new era

NASA Astrophysics Data System (ADS)

Duxbury, Thomas; Smith, David; Robinson, Mark; Zuber, Maria T.; Neumann, Gregory; Danton, Jacob; Oberst, Juergen; Archinal, Brent; Glaeser, Philipp

The Lunar Reconnaissance Orbiter (LRO) ushers in a new era in precision lunar geodesy and cartography. LRO was launched in June, 2009, completed its Commissioning Phase in Septem-ber 2009 and is now in its Primary Mission Phase on its way to collecting high precision, global topographic and imaging data. Aboard LRO are the Lunar Orbiter Laser Altimeter (LOLA -Smith, et al., 2009) and the Lunar Reconnaissance Orbiter Camera (LROC -Robinson, et al., ). LOLA is a derivative of the successful MOLA at Mars that produced the global reference surface being used for all precision cartographic products. LOLA produces 5 altimetry spots having footprints of 5 m at a frequency of 28 Hz, significantly bettering MOLA that produced 1 spot having a footprint of 150 m at a frequency of 10 Hz. LROC has twin narrow angle cameras having pixel resolutions of 0.5 meters from a 50 km orbit and a wide-angle camera having a pixel resolution of 75 m and in up to 7 color bands. One of the two NACs looks to the right of nadir and the other looks to the left with a few hundred pixel overlap in the nadir direction. LOLA is mounted on the LRO spacecraft to look nadir, in the overlap region of the NACs. The LRO spacecraft has the ability to look nadir and build up global coverage as well as looking off-nadir to provide stereo coverage and fill in data gaps. The LROC wide-angle camera builds up global stereo coverage naturally from its large field-of-view overlap from orbit to orbit during nadir viewing. To date, the LROC WAC has already produced global stereo coverage of the lunar surface. This report focuses on the registration of LOLA altimetry to the LROC NAC images. LOLA has a dynamic range of tens of km while producing elevation data at sub-meter precision. LOLA also has good return in off-nadir attitudes. Over the LRO mission, multiple LOLA tracks will be in each of the NAC images at the lunar equator and even more tracks in the NAC images nearer the poles. The registration of LOLA altimetry to NAC images is aided by the 5 spots showing regional and local slopes, along and cross-track, that are easily correlated visually to features within the images. Once can precisely register each of the 5 LOLA spots to specific pixels in LROC images of distinct features such as craters and boulders. This can be performed routinely for features at the 100 m level and larger. However, even features at the several m level can also be registered if a single LOLA spots probes the depth of a small crater while the other 4 spots are on the surrounding surface or one spot returns from the top of a small boulder seen by NAC. The automatic registration of LOLA tracks with NAC stereo digital terrain models should provide for even higher accuracy. Also the LOLA pulse spread of the returned signal, which is sensitive to slopes and roughness, is an additional source of information to help match the LOLA tracks to the images As the global coverage builds, LOLA will provide absolute coordinates in latitude, longitude and radius of surface features with accuracy at the meter level or better. The NAC images will then be reg-istered to the LOLA reference surface in the production of precision, controlled photomosaics, having spatial resolutions as good as 0.5 m/pixel. For hundreds of strategic sites viewed in stereo, even higher precision and more complete surface coverage is possible for the produc-tion of digital terrain models and mosaics. LRO, with LOLA and LROC, will improve the relative and absolute accuracy of geodesy and cartography by orders of magnitude, ushering in a new era for lunar geodesy and cartography. Robinson, M., et al., Space Sci. Rev., DOI 10.1007/s11214-010-9634-2, Date: 2010-02-23, in press. Smith, D., et al., Space Sci. Rev., DOI 10.1007/s11214-009-9512-y, published online 16 May 2009.

Advanced Optical Technologies in NASA's Space Communication Program: Status, Challenges, and Future Plans

NASA Technical Reports Server (NTRS)

Pouch, John

2004-01-01

A goal of the NASA Space Communications Project is to enable broad coverage for high-data-rate delivery to the users by means of ground, air, and space-based assets. The NASA Enterprise need will be reviewed. A number of optical space communications technologies being developed by NASA will be described, and the prospective applications will be discussed.

GLAST and Suzaku

NASA Technical Reports Server (NTRS)

Sambruna, Rita

2007-01-01

The upcoming years will see a formidable synergy of high-energy observatories for the study of extragalactic objects, especially AGN. In particular, the launch of GLAST will allow us coordinated monitoring of sources with Suzaku over a very large energy band, from medium X-rays to GeV energies. In this talk I will review the science issues that such a remarkable coverage will enable us to address.

Deep sequencing with intronic capture enables identification of an APC exon 10 inversion in a patient with polyposis.

PubMed

Shirts, Brian H; Salipante, Stephen J; Casadei, Silvia; Ryan, Shawnia; Martin, Judith; Jacobson, Angela; Vlaskin, Tatyana; Koehler, Karen; Livingston, Robert J; King, Mary-Claire; Walsh, Tom; Pritchard, Colin C

2014-10-01

Single-exon inversions have rarely been described in clinical syndromes and are challenging to detect using Sanger sequencing. We report the case of a 40-year-old woman with adenomatous colon polyps too numerous to count and who had a complex inversion spanning the entire exon 10 in APC (the gene encoding for adenomatous polyposis coli), causing exon skipping and resulting in a frameshift and premature protein truncation. In this study, we employed complete APC gene sequencing using high-coverage next-generation sequencing by ColoSeq, analysis with BreakDancer and SLOPE software, and confirmatory transcript analysis. ColoSeq identified a complex small genomic rearrangement consisting of an inversion that results in translational skipping of exon 10 in the APC gene. This mutation would not have been detected by traditional sequencing or gene-dosage methods. We report a case of adenomatous polyposis resulting from a complex single-exon inversion. Our report highlights the benefits of large-scale sequencing methods that capture intronic sequences with high enough depth of coverage-as well as the use of informatics tools-to enable detection of small pathogenic structural rearrangements.