17 CFR 239.63 - Form ID, uniform application for access codes to file on EDGAR.

Code of Federal Regulations, 2011 CFR

2011-04-01

... for access codes to file on EDGAR. 239.63 Section 239.63 Commodity and Securities Exchanges SECURITIES... Statements § 239.63 Form ID, uniform application for access codes to file on EDGAR. Form ID must be filed by... log on to the EDGAR system, submit filings, and change its CCC. (d) Password Modification...

17 CFR 239.63 - Form ID, uniform application for access codes to file on EDGAR.

Code of Federal Regulations, 2010 CFR

2010-04-01

... for access codes to file on EDGAR. 239.63 Section 239.63 Commodity and Securities Exchanges SECURITIES... Statements § 239.63 Form ID, uniform application for access codes to file on EDGAR. Form ID must be filed by... log on to the EDGAR system, submit filings, and change its CCC. (d) Password Modification...

17 CFR 274.402 - Form ID, uniform application for access codes to file on EDGAR.

Code of Federal Regulations, 2011 CFR

2011-04-01

... for access codes to file on EDGAR. 274.402 Section 274.402 Commodity and Securities Exchanges... Forms for Electronic Filing § 274.402 Form ID, uniform application for access codes to file on EDGAR..., filing agent or training agent to log on to the EDGAR system, submit filings, and change its CCC. (d...

Uniform Federal Accessibility Standards.

ERIC Educational Resources Information Center

Department of Housing and Urban Development, Washington, DC.

The document presents uniform standards for facility accessibility by physically handicapped persons for Federal and federally funded facilities. The standards are to be applied during the design, construction, and alteration of buildings and facilities to the extent required by the Architectural Barriers Act of 1968, as amended. Technical…

The Geodetic Seamless Archive Centers Service Layer: A System Architecture for Federating Geodesy Data Repositories

NASA Astrophysics Data System (ADS)

McWhirter, J.; Boler, F. M.; Bock, Y.; Jamason, P.; Squibb, M. B.; Noll, C. E.; Blewitt, G.; Kreemer, C. W.

2010-12-01

Three geodesy Archive Centers, Scripps Orbit and Permanent Array Center (SOPAC), NASA's Crustal Dynamics Data Information System (CDDIS) and UNAVCO are engaged in a joint effort to define and develop a common Web Service Application Programming Interface (API) for accessing geodetic data holdings. This effort is funded by the NASA ROSES ACCESS Program to modernize the original GPS Seamless Archive Centers (GSAC) technology which was developed in the 1990s. A new web service interface, the GSAC-WS, is being developed to provide uniform and expanded mechanisms through which users can access our data repositories. In total, our respective archives hold tens of millions of files and contain a rich collection of site/station metadata. Though we serve similar user communities, we currently provide a range of different access methods, query services and metadata formats. This leads to a lack of consistency in the userís experience and a duplication of engineering efforts. The GSAC-WS API and its reference implementation in an underlying Java-based GSAC Service Layer (GSL) supports metadata and data queries into site/station oriented data archives. The general nature of this API makes it applicable to a broad range of data systems. The overall goals of this project include providing consistent and rich query interfaces for end users and client programs, the development of enabling technology to facilitate third party repositories in developing these web service capabilities and to enable the ability to perform data queries across a collection of federated GSAC-WS enabled repositories. A fundamental challenge faced in this project is to provide a common suite of query services across a heterogeneous collection of data yet enabling each repository to expose their specific metadata holdings. To address this challenge we are developing a "capabilities" based service where a repository can describe its specific query and metadata capabilities. Furthermore, the architecture of the GSL is based on a model-view paradigm that decouples the underlying data model semantics from particular representations of the data model. This will allow for the GSAC-WS enabled repositories to evolve their service offerings to incorporate new metadata definition formats (e.g., ISO-19115, FGDC, JSON, etc.) and new techniques for accessing their holdings. Building on the core GSAC-WS implementations the project is also developing a federated/distributed query service. This service will seamlessly integrate with the GSAC Service Layer and will support data and metadata queries across a collection of federated GSAC repositories.

Automating testbed documentation and database access using World Wide Web (WWW) tools

NASA Technical Reports Server (NTRS)

Ames, Charles; Auernheimer, Brent; Lee, Young H.

1994-01-01

A method for providing uniform transparent access to disparate distributed information systems was demonstrated. A prototype testing interface was developed to access documentation and information using publicly available hypermedia tools. The prototype gives testers a uniform, platform-independent user interface to on-line documentation, user manuals, and mission-specific test and operations data. Mosaic was the common user interface, and HTML (Hypertext Markup Language) provided hypertext capability.

Calibration-free quantification of interior properties of porous media with x-ray computed tomography.

PubMed

Hussein, Esam M A; Agbogun, H M D; Al, Tom A

2015-03-01

A method is presented for interpreting the values of x-ray attenuation coefficients reconstructed in computed tomography of porous media, while overcoming the ambiguity caused by the multichromatic nature of x-rays, dilution by void, and material heterogeneity. The method enables determination of porosity without relying on calibration or image segmentation or thresholding to discriminate pores from solid material. It distinguishes between solution-accessible and inaccessible pores, and provides the spatial and frequency distributions of solid-matrix material in a heterogeneous medium. This is accomplished by matching an image of a sample saturated with a contrast solution with that saturated with a transparent solution. Voxels occupied with solid-material and inaccessible pores are identified by the fact that they maintain the same location and image attributes in both images, with voxels containing inaccessible pores appearing empty in both images. Fully porous and accessible voxels exhibit the maximum contrast, while the rest are porous voxels containing mixtures of pore solutions and solid. This matching process is performed with an image registration computer code, and image processing software that requires only simple subtraction and multiplication (scaling) processes. The process is demonstrated in dolomite (non-uniform void distribution, homogeneous solid matrix) and sandstone (nearly uniform void distribution, heterogeneous solid matrix) samples, and its overall performance is shown to compare favorably with a method based on calibration and thresholding. Copyright © 2014 Elsevier Ltd. All rights reserved.

Extending the Common Framework for Earth Observation Data to other Disciplinary Data and Programmatic Access

NASA Astrophysics Data System (ADS)

Evans, B. J. K.; Wyborn, L. A.; Druken, K. A.; Richards, C. J.; Trenham, C. E.; Wang, J.

2016-12-01

The Australian National Computational Infrastructure (NCI) manages a large geospatial repository (10+ PBytes) of Earth systems, environmental, water management and geophysics research data, co-located with a petascale supercomputer and an integrated research cloud. NCI has applied the principles of the "Common Framework for Earth-Observation Data" (the Framework) to the organisation of these collections enabling a diverse range of researchers to explore different aspects of the data and, in particular, for seamless programmatic data analysis, both in-situ access and via data services. NCI provides access to the collections through the National Environmental Research Data Interoperability Platform (NERDIP) - a comprehensive and integrated data platform with both common and emerging services designed to enable data accessibility and citability. Applying the Framework across the range of datasets ensures that programmatic access, both in-situ and network methods, work as uniformly as possible for any dataset, using both APIs and data services. NCI has also created a comprehensive quality assurance framework to regularise compliance checks across the data, library APIs and data services, and to establish a comprehensive set of benchmarks to quantify both functionality and performance perspectives for the Framework. The quality assurance includes organisation of datasets through a data management plan, which anchors the data directory structure, version controls and data information services so that they are kept aligned with operational changes over time. Specific attention has been placed on the way data are packed inside the files. Our experience has shown that complying with standards such as CF and ACDD is still not enough to ensure that all data services or software packages correctly read the data. Further, data may not be optimally organised for the different access patterns, which causes poor performance of the CPUs and bandwidth utilisation. We will also discuss some gaps in the Framework that have emerged and our approach to resolving these.

In situ process monitoring in selective laser sintering using optical coherence tomography

NASA Astrophysics Data System (ADS)

Gardner, Michael R.; Lewis, Adam; Park, Jongwan; McElroy, Austin B.; Estrada, Arnold D.; Fish, Scott; Beaman, Joseph J.; Milner, Thomas E.

2018-04-01

Selective laser sintering (SLS) is an efficient process in additive manufacturing that enables rapid part production from computer-based designs. However, SLS is limited by its notable lack of in situ process monitoring when compared with other manufacturing processes. We report the incorporation of optical coherence tomography (OCT) into an SLS system in detail and demonstrate access to surface and subsurface features. Video frame rate cross-sectional imaging reveals areas of sintering uniformity and areas of excessive heat error with high temporal resolution. We propose a set of image processing techniques for SLS process monitoring with OCT and report the limitations and obstacles for further OCT integration with SLS systems.

Dynamic federation of grid and cloud storage

NASA Astrophysics Data System (ADS)

Furano, Fabrizio; Keeble, Oliver; Field, Laurence

2016-09-01

The Dynamic Federations project ("Dynafed") enables the deployment of scalable, distributed storage systems composed of independent storage endpoints. While the Uniform Generic Redirector at the heart of the project is protocol-agnostic, we have focused our effort on HTTP-based protocols, including S3 and WebDAV. The system has been deployed on testbeds covering the majority of the ATLAS and LHCb data, and supports geography-aware replica selection. The work done exploits the federation potential of HTTP to build systems that offer uniform, scalable, catalogue-less access to the storage and metadata ensemble and the possibility of seamless integration of other compatible resources such as those from cloud providers. Dynafed can exploit the potential of the S3 delegation scheme, effectively federating on the fly any number of S3 buckets from different providers and applying a uniform authorization to them. This feature has been used to deploy in production the BOINC Data Bridge, which uses the Uniform Generic Redirector with S3 buckets to harmonize the BOINC authorization scheme with the Grid/X509. The Data Bridge has been deployed in production with good results. We believe that the features of a loosely coupled federation of open-protocolbased storage elements open many possibilities of smoothly evolving the current computing models and of supporting new scientific computing projects that rely on massive distribution of data and that would appreciate systems that can more easily be interfaced with commercial providers and can work natively with Web browsers and clients.

NASA's Astromaterials Database: Enabling Research Through Increased Access to Sample Data, Metadata and Imagery

NASA Technical Reports Server (NTRS)

Evans, Cindy; Todd, Nancy

2014-01-01

The Astromaterials Acquisition & Curation Office at NASA's Johnson Space Center (JSC) is the designated facility for curating all of NASA's extraterrestrial samples. Today, the suite of collections includes the lunar samples from the Apollo missions, cosmic dust particles falling into the Earth's atmosphere, meteorites collected in Antarctica, comet and interstellar dust particles from the Stardust mission, asteroid particles from Japan's Hayabusa mission, solar wind atoms collected during the Genesis mission, and space-exposed hardware from several missions. To support planetary science research on these samples, JSC's Astromaterials Curation Office hosts NASA's Astromaterials Curation digital repository and data access portal [http://curator.jsc.nasa.gov/], providing descriptions of the missions and collections, and critical information about each individual sample. Our office is designing and implementing several informatics initiatives to better serve the planetary research community. First, we are re-hosting the basic database framework by consolidating legacy databases for individual collections and providing a uniform access point for information (descriptions, imagery, classification) on all of our samples. Second, we continue to upgrade and host digital compendia that summarize and highlight published findings on the samples (e.g., lunar samples, meteorites from Mars). We host high resolution imagery of samples as it becomes available, including newly scanned images of historical prints from the Apollo missions. Finally we are creating plans to collect and provide new data, including 3D imagery, point cloud data, micro CT data, and external links to other data sets on selected samples. Together, these individual efforts will provide unprecedented digital access to NASA's Astromaterials, enabling preservation of the samples through more specific and targeted requests, and supporting new planetary science research and collaborations on the samples.

Accessing thermoplastic processing windows in metallic glasses using rapid capacitive discharge

PubMed Central

Kaltenboeck, Georg; Harris, Thomas; Sun, Kerry; Tran, Thomas; Chang, Gregory; Schramm, Joseph P.; Demetriou, Marios D.; Johnson, William L.

2014-01-01

The ability of the rapid-capacitive discharge approach to access optimal viscosity ranges in metallic glasses for thermoplastic processing is explored. Using high-speed thermal imaging, the heating uniformity and stability against crystallization of Zr35Ti30Cu7.5Be27.5 metallic glass heated deeply into the supercooled region is investigated. The method enables homogeneous volumetric heating of bulk samples throughout the entire supercooled liquid region at high rates (~105 K/s) sufficient to bypass crystallization throughout. The crystallization onsets at temperatures in the vicinity of the “crystallization nose” were identified and a Time-Temperature-Transformation diagram is constructed, revealing a “critical heating rate” for the metallic glass of ~1000 K/s. Thermoplastic process windows in the optimal viscosity range of 100–104 Pa·s are identified, being confined between the glass relaxation and the eutectic crystallization transition. Within this process window, near-net forging of a fine precision metallic glass part is demonstrated. PMID:25269892

Zooming in on vibronic structure by lowest-value projection reconstructed 4D coherent spectroscopy

NASA Astrophysics Data System (ADS)

Harel, Elad

2018-05-01

A fundamental goal of chemical physics is an understanding of microscopic interactions in liquids at and away from equilibrium. In principle, this microscopic information is accessible by high-order and high-dimensionality nonlinear optical measurements. Unfortunately, the time required to execute such experiments increases exponentially with the dimensionality, while the signal decreases exponentially with the order of the nonlinearity. Recently, we demonstrated a non-uniform acquisition method based on radial sampling of the time-domain signal [W. O. Hutson et al., J. Phys. Chem. Lett. 9, 1034 (2018)]. The four-dimensional spectrum was then reconstructed by filtered back-projection using an inverse Radon transform. Here, we demonstrate an alternative reconstruction method based on the statistical analysis of different back-projected spectra which results in a dramatic increase in sensitivity and at least a 100-fold increase in dynamic range compared to conventional uniform sampling and Fourier reconstruction. These results demonstrate that alternative sampling and reconstruction methods enable applications of increasingly high-order and high-dimensionality methods toward deeper insights into the vibronic structure of liquids.

The DOI Is Coming.

ERIC Educational Resources Information Center

Scharf, Davida

2002-01-01

Discussion of improving accessibility to copyrighted electronic content focuses on the Digital Object Identifier (DOI) and the Open URL standard and linking software. Highlights include work of the World Wide Web consortium; URI (Uniform Resource Identifier); URL (Uniform Resource Locator); URN (Uniform Resource Name); OCLC's (Online Computer…

Incorporating Brokers within Collaboration Environments

NASA Astrophysics Data System (ADS)

Rajasekar, A.; Moore, R.; de Torcy, A.

2013-12-01

A collaboration environment, such as the integrated Rule Oriented Data System (iRODS - http://irods.diceresearch.org), provides interoperability mechanisms for accessing storage systems, authentication systems, messaging systems, information catalogs, networks, and policy engines from a wide variety of clients. The interoperability mechanisms function as brokers, translating actions requested by clients to the protocol required by a specific technology. The iRODS data grid is used to enable collaborative research within hydrology, seismology, earth science, climate, oceanography, plant biology, astronomy, physics, and genomics disciplines. Although each domain has unique resources, data formats, semantics, and protocols, the iRODS system provides a generic framework that is capable of managing collaborative research initiatives that span multiple disciplines. Each interoperability mechanism (broker) is linked to a name space that enables unified access across the heterogeneous systems. The collaboration environment provides not only support for brokers, but also support for virtualization of name spaces for users, files, collections, storage systems, metadata, and policies. The broker enables access to data or information in a remote system using the appropriate protocol, while the collaboration environment provides a uniform naming convention for accessing and manipulating each object. Within the NSF DataNet Federation Consortium project (http://www.datafed.org), three basic types of interoperability mechanisms have been identified and applied: 1) drivers for managing manipulation at the remote resource (such as data subsetting), 2) micro-services that execute the protocol required by the remote resource, and 3) policies for controlling the execution. For example, drivers have been written for manipulating NetCDF and HDF formatted files within THREDDS servers. Micro-services have been written that manage interactions with the CUAHSI data repository, the DataONE information catalog, and the GeoBrain broker. Policies have been written that manage transfer of messages between an iRODS message queue and the Advanced Message Queuing Protocol. Examples of these brokering mechanisms will be presented. The DFC collaboration environment serves as the intermediary between community resources and compute grids, enabling reproducible data-driven research. It is possible to create an analysis workflow that retrieves data subsets from a remote server, assemble the required input files, automate the execution of the workflow, automatically track the provenance of the workflow, and share the input files, workflow, and output files. A collaborator can re-execute a shared workflow, compare results, change input files, and re-execute an analysis.

Interoperable Solar Data and Metadata via LISIRD 3

NASA Astrophysics Data System (ADS)

Wilson, A.; Lindholm, D. M.; Pankratz, C. K.; Snow, M. A.; Woods, T. N.

2015-12-01

LISIRD 3 is a major upgrade of the LASP Interactive Solar Irradiance Data Center (LISIRD), which serves several dozen space based solar irradiance and related data products to the public. Through interactive plots, LISIRD 3 provides data browsing supported by data subsetting and aggregation. Incorporating a semantically enabled metadata repository, LISIRD 3 users see current, vetted, consistent information about the datasets offered. Users can now also search for datasets based on metadata fields such as dataset type and/or spectral or temporal range. This semantic database enables metadata browsing, so users can discover the relationships between datasets, instruments, spacecraft, mission and PI. The database also enables creation and publication of metadata records in a variety of formats, such as SPASE or ISO, making these datasets more discoverable. The database also enables the possibility of a public SPARQL endpoint, making the metadata browsable in an automated fashion. LISIRD 3's data access middleware, LaTiS, provides dynamic, on demand reformatting of data and timestamps, subsetting and aggregation, and other server side functionality via a RESTful OPeNDAP compliant API, enabling interoperability between LASP datasets and many common tools. LISIRD 3's templated front end design, coupled with the uniform data interface offered by LaTiS, allows easy integration of new datasets. Consequently the number and variety of datasets offered by LISIRD has grown to encompass several dozen, with many more to come. This poster will discuss design and implementation of LISIRD 3, including tools used, capabilities enabled, and issues encountered.

Droplet Digital™ PCR Next-Generation Sequencing Library QC Assay.

PubMed

Heredia, Nicholas J

2018-01-01

Digital PCR is a valuable tool to quantify next-generation sequencing (NGS) libraries precisely and accurately. Accurately quantifying NGS libraries enable accurate loading of the libraries on to the sequencer and thus improve sequencing performance by reducing under and overloading error. Accurate quantification also benefits users by enabling uniform loading of indexed/barcoded libraries which in turn greatly improves sequencing uniformity of the indexed/barcoded samples. The advantages gained by employing the Droplet Digital PCR (ddPCR™) library QC assay includes the precise and accurate quantification in addition to size quality assessment, enabling users to QC their sequencing libraries with confidence.

Enabling locally-developed content for access through the infobutton by means of automated concept annotation.

PubMed

Hulse, Nathan C; Long, Jie; Xu, Xiaomin; Tao, Cui

2014-01-01

Infobuttons have proven to be an increasingly important resource in providing a standardized approach to integrating useful educational materials at the point of care in electronic health records (EHRs). They provide a simple, uniform pathway for both patients and providers to receive pertinent education materials in a quick fashion from within EHRs and Personalized Health Records (PHRs). In recent years, the international standards organization Health Level Seven has balloted and approved a standards-based pathway for requesting and receiving data for infobuttons, simplifying some of the barriers for their adoption in electronic medical records and amongst content providers. Local content, developed by the hosting organization themselves, still needs to be indexed and annotated with appropriate metadata and terminologies in order to be fully accessible via the infobutton. In this manuscript we present an approach for automating the annotation of internally-developed patient education sheets with standardized terminologies and compare and contrast the approach with manual approaches used previously. We anticipate that a combination of system-generated and human reviewed annotations will provide the most comprehensive and effective indexing strategy, thereby allowing best access to internally-created content via the infobutton.

MemAxes: Visualization and Analytics for Characterizing Complex Memory Performance Behaviors.

PubMed

Gimenez, Alfredo; Gamblin, Todd; Jusufi, Ilir; Bhatele, Abhinav; Schulz, Martin; Bremer, Peer-Timo; Hamann, Bernd

2018-07-01

Memory performance is often a major bottleneck for high-performance computing (HPC) applications. Deepening memory hierarchies, complex memory management, and non-uniform access times have made memory performance behavior difficult to characterize, and users require novel, sophisticated tools to analyze and optimize this aspect of their codes. Existing tools target only specific factors of memory performance, such as hardware layout, allocations, or access instructions. However, today's tools do not suffice to characterize the complex relationships between these factors. Further, they require advanced expertise to be used effectively. We present MemAxes, a tool based on a novel approach for analytic-driven visualization of memory performance data. MemAxes uniquely allows users to analyze the different aspects related to memory performance by providing multiple visual contexts for a centralized dataset. We define mappings of sampled memory access data to new and existing visual metaphors, each of which enabling a user to perform different analysis tasks. We present methods to guide user interaction by scoring subsets of the data based on known performance problems. This scoring is used to provide visual cues and automatically extract clusters of interest. We designed MemAxes in collaboration with experts in HPC and demonstrate its effectiveness in case studies.

Flexible polymer waveguides for light-activated therapy (Conference Presentation)

NASA Astrophysics Data System (ADS)

Kim, Moonseok; Kwok, Sheldon J. J.; Lin, Harvey H.; Lee, Dong Hee; Yun, Seok Hyun

2017-02-01

Conventional light-activated therapies, such as photodynamic therapy (PDT), photochemical tissue bonding (PTB), collagen crosslinking (CXL), low-level light therapy (LLLT), and antimicrobial therapy utilize external light sources and light propagation through free space, limiting treatment to accessible and superficial areas of the body. Recent progress has been made in developing biocompatible polymer waveguides to enhance light delivery to deep tissues. To further expand clinical utility, waveguides should be flexible and tough enough to enable use in anatomically difficult-to-reach regions, while having the requisite optical properties to achieve uniform and efficient illumination of the target area. Here, we present a new class of flexible polymer waveguides optimized for uniform light extraction into tissues. Our slab waveguides comprise two designs: first, a flexible polydimethylsiloxane (PDMS) based elastomer for CXL, and second, a tough polyacrylamide and alginate hydrogel for large-area phototherapies. Our waveguides are optically transparent in the visible wavelengths (400-750 nm) and a multimode fiber is used to couple light into the waveguide. We characterized the light propagation through the waveguides and light extraction into tissue, and validated our results with optical simulation. By changing the thickness and scattering properties, uniform light extraction through the length of the waveguide could be achieved. We demonstrate proof-of-concept scleral photo-crosslinking of an ex vivo porcine eyeball for prevention of myopia.

Parallel generation of uniform fine droplets at hundreds of kilohertz in a flow-focusing module.

PubMed

Bardin, David; Kendall, Michael R; Dayton, Paul A; Lee, Abraham P

2013-01-01

Droplet-based microfluidic systems enable a variety of biomedical applications from point-of-care diagnostics with third world implications, to targeted therapeutics alongside medical ultrasound, to molecular screening and genetic testing. Though these systems maintain the key advantage of precise control of the size and composition of the droplet as compared to conventional methods of production, the low rates at which droplets are produced limits translation beyond the laboratory setting. As well, previous attempts to scale up shear-based microfluidic systems focused on increasing the volumetric throughput and formed large droplets, negating many practical applications of emulsions such as site-specific therapeutics. We present the operation of a parallel module with eight flow-focusing orifices in the dripping regime of droplet formation for the generation of uniform fine droplets at rates in the hundreds of kilohertz. Elevating the capillary number to access dripping, generation of monodisperse droplets of liquid perfluoropentane in the parallel module exceeded 3.69 × 10(5) droplets per second, or 1.33 × 10(9) droplets per hour, at a mean diameter of 9.8 μm. Our microfluidic method offers a novel means to amass uniform fine droplets in practical amounts, for instance, to satisfy clinical needs, with the potential for modification to form massive amounts of more complex droplets.

Web accessibility and open source software.

PubMed

Obrenović, Zeljko

2009-07-01

A Web browser provides a uniform user interface to different types of information. Making this interface universally accessible and more interactive is a long-term goal still far from being achieved. Universally accessible browsers require novel interaction modalities and additional functionalities, for which existing browsers tend to provide only partial solutions. Although functionality for Web accessibility can be found as open source and free software components, their reuse and integration is complex because they were developed in diverse implementation environments, following standards and conventions incompatible with the Web. To address these problems, we have started several activities that aim at exploiting the potential of open-source software for Web accessibility. The first of these activities is the development of Adaptable Multi-Interface COmmunicator (AMICO):WEB, an infrastructure that facilitates efficient reuse and integration of open source software components into the Web environment. The main contribution of AMICO:WEB is in enabling the syntactic and semantic interoperability between Web extension mechanisms and a variety of integration mechanisms used by open source and free software components. Its design is based on our experiences in solving practical problems where we have used open source components to improve accessibility of rich media Web applications. The second of our activities involves improving education, where we have used our platform to teach students how to build advanced accessibility solutions from diverse open-source software. We are also partially involved in the recently started Eclipse projects called Accessibility Tools Framework (ACTF), the aim of which is development of extensible infrastructure, upon which developers can build a variety of utilities that help to evaluate and enhance the accessibility of applications and content for people with disabilities. In this article we briefly report on these activities.

Roll-to-Roll Nanoforming of Metals Using Laser-Induced Superplasticity.

PubMed

Goswami, Debkalpa; Munera, Juan C; Pal, Aniket; Sadri, Behnam; Scarpetti, Caio Lui P G; Martinez, Ramses V

2018-05-24

This Letter describes a low-cost, scalable nanomanufacturing process that enables the continuous forming of thin metallic layers with nanoscale accuracy using roll-to-roll, laser-induced superplasticity (R2RLIS). R2RLIS uses a laser shock to induce the ultrahigh-strain-rate deformation of metallic films at room temperature into low-cost polymeric nanomolds, independently of the original grain size of the metal. This simple and inexpensive nanoforming method does not require access to cleanrooms and associated facilities, and can be easily implemented on conventional CO 2 lasers, enabling laser systems commonly used for rapid prototyping or industrial cutting and engraving to fabricate uniform and three-dimensional crystalline metallic nanostructures over large areas. Tuning the laser power during the R2RLIS process enables the control of the aspect ratio and the mechanical and optical properties of the fabricated nanostructures. This roll-to-roll technique successfully fabricates mechanically strengthened gold plasmonic nanostructures with aspect ratios as high as 5 that exhibit high oxidation resistance and strong optical field enhancements. The CO 2 laser used in R2RLIS can also integrate the fabricated nanostructures on transparent flexible substrates with robust interfacial contact. The ability to fabricate ultrasmooth metallic nanostructures using roll-to-roll manufacturing enables the large scale production, at a relatively low-cost, of flexible plasmonic devices toward emerging applications.

Continuous flow, explosives vapor generator and sensor chamber.

PubMed

Collins, Greg E; Giordano, Braden C; Sivaprakasam, Vasanthi; Ananth, Ramagopal; Hammond, Mark; Merritt, Charles D; Tucker, John E; Malito, Michael; Eversole, Jay D; Rose-Pehrsson, Susan

2014-05-01

A novel liquid injection vapor generator (LIVG) is demonstrated that is amenable to low vapor pressure explosives, 2,4,6-trinitrotoluene and hexahydro-1,3,5-trinitro-1,3,5-triazine. The LIVG operates in a continuous manner, providing a constant and stable vapor output over a period of days and whose concentration can be extended over as much as three orders of magnitude. In addition, a large test atmosphere chamber attached to the LIVG is described, which enables the generation of a stable test atmosphere with controllable humidity and temperature. The size of the chamber allows for the complete insertion of testing instruments or arrays of materials into a uniform test atmosphere, and various electrical feedthroughs, insertion ports, and sealed doors permit simple and effective access to the sample chamber and its vapor.

Performance Analysis of Modified Accelerative Preallocation MAC Protocol for Passive Star-Coupled WDMA Networks

NASA Astrophysics Data System (ADS)

Yun, Changho; Kim, Kiseon

2006-04-01

For the passive star-coupled wavelength-division multiple-access (WDMA) network, a modified accelerative preallocation WDMA (MAP-WDMA) media access control (MAC) protocol is proposed, which is based on AP-WDMA. To show the advantages of MAP-WDMA as an adequate MAC protocol for the network over AP-WDMA, the channel utilization, the channel-access delay, and the latency of MAP-WDMA are investigated and compared with those of AP-WDMA under various data traffic patterns, including uniform, quasi-uniform type, disconnected type, mesh type, and ring type data traffics, as well as the assumption that a given number of network stations is equal to that of channels, in other words, without channel sharing. As a result, the channel utilization of MAP-WDMA can be competitive with respect to that of AP-WDMA at the expense of insignificantly higher latency. Namely, if the number of network stations is small, MAP-WDMA provides better channel utilization for uniform, quasi-uniform-type, and disconnected-type data traffics at all data traffic loads, as well as for mesh and ring-type data traffics at low data traffic loads. Otherwise, MAP-WDMA only outperforms AP-WDMA for the first three data traffics at higher data traffic loads. In the aspect of channel-access delay, MAP-WDMA gives better performance than AP-WDMA, regardless of data traffic patterns and the number of network stations.

7 CFR 3015.24 - Access to records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Access to records. 3015.24 Section 3015.24 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF AGRICULTURE UNIFORM FEDERAL ASSISTANCE REGULATIONS Record Retention and Access Requirements...

47 CFR 32.5083 - Special access revenue.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 2 2011-10-01 2011-10-01 false Special access revenue. 32.5083 Section 32.5083 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES UNIFORM SYSTEM OF ACCOUNTS FOR TELECOMMUNICATIONS COMPANIES Instructions For Revenue Accounts § 32.5083 Special access revenue...

47 CFR 32.5083 - Special access revenue.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 2 2014-10-01 2014-10-01 false Special access revenue. 32.5083 Section 32.5083 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES UNIFORM SYSTEM OF ACCOUNTS FOR TELECOMMUNICATIONS COMPANIES Instructions For Revenue Accounts § 32.5083 Special access revenue...

Using OSG Computing Resources with (iLC)Dirac

NASA Astrophysics Data System (ADS)

Sailer, A.; Petric, M.; CLICdp Collaboration

2017-10-01

CPU cycles for small experiments and projects can be scarce, thus making use of all available resources, whether dedicated or opportunistic, is mandatory. While enabling uniform access to the LCG computing elements (ARC, CREAM), the DIRAC grid interware was not able to use OSG computing elements (GlobusCE, HTCondor-CE) without dedicated support at the grid site through so called ‘SiteDirectors’, which directly submit to the local batch system. This in turn requires additional dedicated effort for small experiments on the grid site. Adding interfaces to the OSG CEs through the respective grid middleware is therefore allowing accessing them within the DIRAC software without additional site-specific infrastructure. This enables greater use of opportunistic resources for experiments and projects without dedicated clusters or an established computing infrastructure with the DIRAC software. To allow sending jobs to HTCondor-CE and legacy Globus computing elements inside DIRAC the required wrapper classes were developed. Not only is the usage of these types of computing elements now completely transparent for all DIRAC instances, which makes DIRAC a flexible solution for OSG based virtual organisations, but it also allows LCG Grid Sites to move to the HTCondor-CE software, without shutting DIRAC based VOs out of their site. In these proceedings we detail how we interfaced the DIRAC system to the HTCondor-CE and Globus computing elements and explain the encountered obstacles and solutions developed, and how the linear collider community uses resources in the OSG.

7 CFR 3015.25 - Restrictions to public access.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Restrictions to public access. 3015.25 Section 3015.25 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF AGRICULTURE UNIFORM FEDERAL ASSISTANCE REGULATIONS Record Retention and Access...

In-Depth Understanding. A Computer Model of Integrated Processing for Narrative Comprehension.

DTIC Science & Technology

1982-05-01

Mr. Smith at the First National Bank , which he had never returned. 218 Although both SY-I and DIVORCE-I involve the lending and returning of money...CLOTHESO. "Clothes are also changed as an enablement for a social activity. For example, pajamas enable sleeping and football uniform@ enable playing

Scalable randomized benchmarking of non-Clifford gates

NASA Astrophysics Data System (ADS)

Cross, Andrew; Magesan, Easwar; Bishop, Lev; Smolin, John; Gambetta, Jay

Randomized benchmarking is a widely used experimental technique to characterize the average error of quantum operations. Benchmarking procedures that scale to enable characterization of n-qubit circuits rely on efficient procedures for manipulating those circuits and, as such, have been limited to subgroups of the Clifford group. However, universal quantum computers require additional, non-Clifford gates to approximate arbitrary unitary transformations. We define a scalable randomized benchmarking procedure over n-qubit unitary matrices that correspond to protected non-Clifford gates for a class of stabilizer codes. We present efficient methods for representing and composing group elements, sampling them uniformly, and synthesizing corresponding poly (n) -sized circuits. The procedure provides experimental access to two independent parameters that together characterize the average gate fidelity of a group element. We acknowledge support from ARO under Contract W911NF-14-1-0124.

24 CFR 40.7 - Availability of Accessibility Standards.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Standards. 40.7 Section 40.7 Housing and Urban Development Office of the Secretary, Department of Housing... OWNED RESIDENTIAL STRUCTURES § 40.7 Availability of Accessibility Standards. Copies of the Uniform Federal Accessibility Standards are available from the Office of Fair Housing and Equal Opportunity, U.S...

75 FR 51984 - Federal Advisory Committee; Meeting of the Uniform Formulary Beneficiary Advisory Panel

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-24

... and Therapeutics Committee regarding the Uniform Formulary. Meeting Agenda Sign-In; Welcome and Opening Remarks; Public Citizen Comments; Scheduled Therapeutic Class Reviews--Ophthalmic Agents...; Panel Discussions and Vote; and comments following each therapeutic class review. Meeting Accessibility...

Editorial: Next Generation Access Networks

NASA Astrophysics Data System (ADS)

Ruffini, Marco; Cincotti, Gabriella; Pizzinat, Anna; Vetter, Peter

2015-12-01

Over the past decade we have seen an increasing number of operators deploying Fibre-to-the-home (FTTH) solutions in access networks, in order to provide home users with a much needed network access upgrade, to support higher peak rates, higher sustained rates and a better and more uniform broadband coverage of the territory.

Collaborative Indoor Access Point Localization Using Autonomous Mobile Robot Swarm.

PubMed

Awad, Fahed; Naserllah, Muhammad; Omar, Ammar; Abu-Hantash, Alaa; Al-Taj, Abrar

2018-01-31

Localization of access points has become an important research problem due to the wide range of applications it addresses such as dismantling critical security threats caused by rogue access points or optimizing wireless coverage of access points within a service area. Existing proposed solutions have mostly relied on theoretical hypotheses or computer simulation to demonstrate the efficiency of their methods. The techniques that rely on estimating the distance using samples of the received signal strength usually assume prior knowledge of the signal propagation characteristics of the indoor environment in hand and tend to take a relatively large number of uniformly distributed random samples. This paper presents an efficient and practical collaborative approach to detect the location of an access point in an indoor environment without any prior knowledge of the environment. The proposed approach comprises a swarm of wirelessly connected mobile robots that collaboratively and autonomously collect a relatively small number of non-uniformly distributed random samples of the access point's received signal strength. These samples are used to efficiently and accurately estimate the location of the access point. The experimental testing verified that the proposed approach can identify the location of the access point in an accurate and efficient manner.

Collaborative Indoor Access Point Localization Using Autonomous Mobile Robot Swarm

PubMed Central

Awad, Fahed; Naserllah, Muhammad; Omar, Ammar; Abu-Hantash, Alaa; Al-Taj, Abrar

2018-01-01

Localization of access points has become an important research problem due to the wide range of applications it addresses such as dismantling critical security threats caused by rogue access points or optimizing wireless coverage of access points within a service area. Existing proposed solutions have mostly relied on theoretical hypotheses or computer simulation to demonstrate the efficiency of their methods. The techniques that rely on estimating the distance using samples of the received signal strength usually assume prior knowledge of the signal propagation characteristics of the indoor environment in hand and tend to take a relatively large number of uniformly distributed random samples. This paper presents an efficient and practical collaborative approach to detect the location of an access point in an indoor environment without any prior knowledge of the environment. The proposed approach comprises a swarm of wirelessly connected mobile robots that collaboratively and autonomously collect a relatively small number of non-uniformly distributed random samples of the access point’s received signal strength. These samples are used to efficiently and accurately estimate the location of the access point. The experimental testing verified that the proposed approach can identify the location of the access point in an accurate and efficient manner. PMID:29385042

The Computing and Data Grid Approach: Infrastructure for Distributed Science Applications

NASA Technical Reports Server (NTRS)

Johnston, William E.

2002-01-01

With the advent of Grids - infrastructure for using and managing widely distributed computing and data resources in the science environment - there is now an opportunity to provide a standard, large-scale, computing, data, instrument, and collaboration environment for science that spans many different projects and provides the required infrastructure and services in a relatively uniform and supportable way. Grid technology has evolved over the past several years to provide the services and infrastructure needed for building 'virtual' systems and organizations. We argue that Grid technology provides an excellent basis for the creation of the integrated environments that can combine the resources needed to support the large- scale science projects located at multiple laboratories and universities. We present some science case studies that indicate that a paradigm shift in the process of science will come about as a result of Grids providing transparent and secure access to advanced and integrated information and technologies infrastructure: powerful computing systems, large-scale data archives, scientific instruments, and collaboration tools. These changes will be in the form of services that can be integrated with the user's work environment, and that enable uniform and highly capable access to these computers, data, and instruments, regardless of the location or exact nature of these resources. These services will integrate transient-use resources like computing systems, scientific instruments, and data caches (e.g., as they are needed to perform a simulation or analyze data from a single experiment); persistent-use resources. such as databases, data catalogues, and archives, and; collaborators, whose involvement will continue for the lifetime of a project or longer. While we largely address large-scale science in this paper, Grids, particularly when combined with Web Services, will address a broad spectrum of science scenarios. both large and small scale.

A study on the evaporation process with multiple point-sources

NASA Astrophysics Data System (ADS)

Jun, Sunghoon; Kim, Minseok; Kim, Suk Han; Lee, Moon Yong; Lee, Eung Ki

2013-10-01

In Organic Light Emitting Display (OLED) manufacturing processes, there is a need to enlarge the mother glass substrate to raise its productivity and enable OLED TV. The larger the size of the glass substrate, the more difficult it is to establish a uniform thickness profile of the organic thin-film layer in the vacuum evaporation process. In this paper, a multiple point-source evaporation process is proposed to deposit a uniform organic layer uniformly. Using this method, a uniformity of 3.75% was achieved along a 1,300 mm length of Gen. 5.5 glass substrate (1300 × 1500 mm2).

Use of Emerging Grid Computing Technologies for the Analysis of LIGO Data

NASA Astrophysics Data System (ADS)

Koranda, Scott

2004-03-01

The LIGO Scientific Collaboration (LSC) today faces the challenge of enabling analysis of terabytes of LIGO data by hundreds of scientists from institutions all around the world. To meet this challenge the LSC is developing tools, infrastructure, applications, and expertise leveraging Grid Computing technologies available today, and making available to LSC scientists compute resources at sites across the United States and Europe. We use digital credentials for strong and secure authentication and authorization to compute resources and data. Building on top of products from the Globus project for high-speed data transfer and information discovery we have created the Lightweight Data Replicator (LDR) to securely and robustly replicate data to resource sites. We have deployed at our computing sites the Virtual Data Toolkit (VDT) Server and Client packages, developed in collaboration with our partners in the GriPhyN and iVDGL projects, providing uniform access to distributed resources for users and their applications. Taken together these Grid Computing technologies and infrastructure have formed the LSC DataGrid--a coherent and uniform environment across two continents for the analysis of gravitational-wave detector data. Much work, however, remains in order to scale current analyses and recent lessons learned need to be integrated into the next generation of Grid middleware.

Human Capital: DoD Compliance With the Uniformed and Overseas Citizens Absentee Voting Act

DTIC Science & Technology

2003-03-31

UVAOs to perform their duties: “last day to mail” notifications to uniformed absentee voters; access to information regarding voter registration...the scope of our research on absentee voting issues that were brought to our attention by uniformed absentee voters. We performed this evaluation...and Overseas Citizens Absentee Voting Act (D-2003-072) Report Documentation Page Report Date 31 Mar 2003 Report Type N/A Dates Covered (from... to

Unlocking the potential of publicly available microarray data using inSilicoDb and inSilicoMerging R/Bioconductor packages.

PubMed

Taminau, Jonatan; Meganck, Stijn; Lazar, Cosmin; Steenhoff, David; Coletta, Alain; Molter, Colin; Duque, Robin; de Schaetzen, Virginie; Weiss Solís, David Y; Bersini, Hugues; Nowé, Ann

2012-12-24

With an abundant amount of microarray gene expression data sets available through public repositories, new possibilities lie in combining multiple existing data sets. In this new context, analysis itself is no longer the problem, but retrieving and consistently integrating all this data before delivering it to the wide variety of existing analysis tools becomes the new bottleneck. We present the newly released inSilicoMerging R/Bioconductor package which, together with the earlier released inSilicoDb R/Bioconductor package, allows consistent retrieval, integration and analysis of publicly available microarray gene expression data sets. Inside the inSilicoMerging package a set of five visual and six quantitative validation measures are available as well. By providing (i) access to uniformly curated and preprocessed data, (ii) a collection of techniques to remove the batch effects between data sets from different sources, and (iii) several validation tools enabling the inspection of the integration process, these packages enable researchers to fully explore the potential of combining gene expression data for downstream analysis. The power of using both packages is demonstrated by programmatically retrieving and integrating gene expression studies from the InSilico DB repository [https://insilicodb.org/app/].

25 CFR 47.6 - Who has access to local education financial records?

Code of Federal Regulations, 2012 CFR

2012-04-01

... Section 47.6 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION UNIFORM DIRECT FUNDING AND SUPPORT FOR BUREAU-OPERATED SCHOOLS § 47.6 Who has access to local education financial records... representatives have access for audit and explanation purposes to any of the local school's accounts, documents...

25 CFR 47.6 - Who has access to local education financial records?

Code of Federal Regulations, 2011 CFR

2011-04-01

... Section 47.6 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION UNIFORM DIRECT FUNDING AND SUPPORT FOR BUREAU-OPERATED SCHOOLS § 47.6 Who has access to local education financial records... representatives have access for audit and explanation purposes to any of the local school's accounts, documents...

25 CFR 47.6 - Who has access to local education financial records?

Code of Federal Regulations, 2013 CFR

2013-04-01

... Section 47.6 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION UNIFORM DIRECT FUNDING AND SUPPORT FOR BUREAU-OPERATED SCHOOLS § 47.6 Who has access to local education financial records... representatives have access for audit and explanation purposes to any of the local school's accounts, documents...

25 CFR 47.6 - Who has access to local education financial records?

Code of Federal Regulations, 2014 CFR

2014-04-01

... Section 47.6 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION UNIFORM DIRECT FUNDING AND SUPPORT FOR BUREAU-OPERATED SCHOOLS § 47.6 Who has access to local education financial records... representatives have access for audit and explanation purposes to any of the local school's accounts, documents...

25 CFR 47.6 - Who has access to local education financial records?

Code of Federal Regulations, 2010 CFR

2010-04-01

... Section 47.6 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION UNIFORM DIRECT FUNDING AND SUPPORT FOR BUREAU-OPERATED SCHOOLS § 47.6 Who has access to local education financial records... representatives have access for audit and explanation purposes to any of the local school's accounts, documents...

Simplifying the Analysis of Data from Multiple Heliophysics Instruments and Missions

NASA Astrophysics Data System (ADS)

Bazell, D.; Vandegriff, J. D.

2014-12-01

Understanding the intertwined plasma, particles and fields connecting the Sun and the Earth requires combining data from many diverse sources, but there are still many technological barriers that complicate the merging of data from different instruments and missions. We present an emerging data serving capability that provides a uniform way to access heterogeneous and distributed data. The goal of our data server is to provide a standardized data access mechanism that is identical for data of any format and layout (CDF, custom binary, FITS, netCDF, CSV and other flavors of ASCII, etc). Data remain in their original format and location (i.e., at instrument team sites or existing data centers), and our data server delivers a dynamically reformatted view of the data. Scientists can then use tools (clients that talk to the server) that offer a single interface for browsing, analyzing or downloading many different contemporary and legacy heliophysics data sets. Our current server accesses many CDF data resources at CDAWeb, as well as multiple other instrument team sites. Our webservice will be deployed on the Amazon Cloud at http://datashop.elasticbeanstalk.com/. Two basic clients will also be demonstrated: one in Java and one in IDL. Python, Perl, and Matlab clients are also planned. Complex missions such as Solar Orbiter and Solar Probe Plus will benefit greatly from tools that enable multi-instrument and multi-mission data comparison.

Evolution of grid-wide access to database resident information in ATLAS using Frontier

NASA Astrophysics Data System (ADS)

Barberis, D.; Bujor, F.; de Stefano, J.; Dewhurst, A. L.; Dykstra, D.; Front, D.; Gallas, E.; Gamboa, C. F.; Luehring, F.; Walker, R.

2012-12-01

The ATLAS experiment deployed Frontier technology worldwide during the initial year of LHC collision data taking to enable user analysis jobs running on the Worldwide LHC Computing Grid to access database resident data. Since that time, the deployment model has evolved to optimize resources, improve performance, and streamline maintenance of Frontier and related infrastructure. In this presentation we focus on the specific changes in the deployment and improvements undertaken, such as the optimization of cache and launchpad location, the use of RPMs for more uniform deployment of underlying Frontier related components, improvements in monitoring, optimization of fail-over, and an increasing use of a centrally managed database containing site specific information (for configuration of services and monitoring). In addition, analysis of Frontier logs has allowed us a deeper understanding of problematic queries and understanding of use cases. Use of the system has grown beyond user analysis and subsystem specific tasks such as calibration and alignment, extending into production processing areas, such as initial reconstruction and trigger reprocessing. With a more robust and tuned system, we are better equipped to satisfy the still growing number of diverse clients and the demands of increasingly sophisticated processing and analysis.

Electronic patient record and archive of records in Cardio.net system for telecardiology.

PubMed

Sierdziński, Janusz; Karpiński, Grzegorz

2003-01-01

In modern medicine the well structured patient data set, fast access to it and reporting capability become an important question. With the dynamic development of information technology (IT) such question is solved via building electronic patient record (EPR) archives. We then obtain fast access to patient data, diagnostic and treatment protocols etc. It results in more efficient, better and cheaper treatment. The aim of the work was to design a uniform Electronic Patient Record, implemented in cardio.net system for telecardiology allowing the co-operation among regional hospitals and reference centers. It includes questionnaires for demographic data and questionnaires supporting doctor's work (initial diagnosis, final diagnosis, history and physical, ECG at the discharge, applied treatment, additional tests, drugs, daily and periodical reports). The browser is implemented in EPR archive to facilitate data retrieval. Several tools for creating EPR and EPR archive were used such as: XML, PHP, Java Script and MySQL. The separate question is the security of data on WWW server. The security is ensured via Security Socket Layer (SSL) protocols and other tools. EPR in Cardio.net system is a module enabling the co-work of many physicians and the communication among different medical centers.

45 CFR 1151.23 - New construction.

Code of Federal Regulations, 2010 CFR

2010-10-01

... HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS NONDISCRIMINATION ON THE BASIS OF HANDICAP Discrimination... shall be designed and constructed to be readily accessible to and usable by handicapped persons... readily accessible to and usable by handicapped persons. (b) Conformance with Uniform Federal...

45 CFR 1151.23 - New construction.

Code of Federal Regulations, 2014 CFR

2014-10-01

... HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS NONDISCRIMINATION ON THE BASIS OF HANDICAP Discrimination... shall be designed and constructed to be readily accessible to and usable by handicapped persons... readily accessible to and usable by handicapped persons. (b) Conformance with Uniform Federal...

45 CFR 1151.23 - New construction.

Code of Federal Regulations, 2012 CFR

2012-10-01

... HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS NONDISCRIMINATION ON THE BASIS OF HANDICAP Discrimination... shall be designed and constructed to be readily accessible to and usable by handicapped persons... readily accessible to and usable by handicapped persons. (b) Conformance with Uniform Federal...

45 CFR 1151.23 - New construction.

Code of Federal Regulations, 2011 CFR

2011-10-01

... HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS NONDISCRIMINATION ON THE BASIS OF HANDICAP Discrimination... shall be designed and constructed to be readily accessible to and usable by handicapped persons... readily accessible to and usable by handicapped persons. (b) Conformance with Uniform Federal...

45 CFR 1151.23 - New construction.

Code of Federal Regulations, 2013 CFR

2013-10-01

... HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS NONDISCRIMINATION ON THE BASIS OF HANDICAP Discrimination... shall be designed and constructed to be readily accessible to and usable by handicapped persons... readily accessible to and usable by handicapped persons. (b) Conformance with Uniform Federal...

Optimizing the LSST Dither Pattern for Survey Uniformity

NASA Astrophysics Data System (ADS)

Awan, Humna; Gawiser, Eric J.; Kurczynski, Peter; Carroll, Christopher M.; LSST Dark Energy Science Collaboration

2015-01-01

The Large Synoptic Survey Telescope (LSST) will gather detailed data of the southern sky, enabling unprecedented study of Baryonic Acoustic Oscillations, which are an important probe of dark energy. These studies require a survey with highly uniform depth, and we aim to find an observation strategy that optimizes this uniformity. We have shown that in the absence of dithering (large telescope-pointing offsets), the LSST survey will vary significantly in depth. Hence, we implemented various dithering strategies, including random and repulsive random pointing offsets and spiral patterns with the spiral reaching completion in either a few months or the entire ten-year run. We employed three different implementations of dithering strategies: a single offset assigned to all fields observed on each night, offsets assigned to each field independently whenever the field is observed, and offsets assigned to each field only when the field is observed on a new night. Our analysis reveals that large dithers are crucial to guarantee survey uniformity and that assigning dithers to each field independently whenever the field is observed significantly increases this uniformity. These results suggest paths towards an optimal observation strategy that will enable LSST to achieve its science goals.We gratefully acknowledge support from the National Science Foundation REU program at Rutgers, PHY-1263280, and the Department of Energy, DE-SC0011636.

Roll-to-Roll Gravure Printed Electrochemical Sensors for Wearable and Medical Devices.

PubMed

Bariya, Mallika; Shahpar, Ziba; Park, Hyejin; Sun, Junfeng; Jung, Younsu; Gao, Wei; Nyein, Hnin Yin Yin; Liaw, Tiffany Sun; Tai, Li-Chia; Ngo, Quynh P; Chao, Minghan; Zhao, Yingbo; Hettick, Mark; Cho, Gyoujin; Javey, Ali

2018-06-25

As recent developments in noninvasive biosensors spearhead the thrust toward personalized health and fitness monitoring, there is a need for high throughput, cost-effective fabrication of flexible sensing components. Toward this goal, we present roll-to-roll (R2R) gravure printed electrodes that are robust under a range of electrochemical sensing applications. We use inks and electrode morphologies designed for electrochemical and mechanical stability, achieving devices with uniform redox kinetics printed on 150 m flexible substrate rolls. We show that these electrodes can be functionalized into consistently high performing sensors for detecting ions, metabolites, heavy metals, and other small molecules in noninvasively accessed biofluids, including sensors for real-time, in situ perspiration monitoring during exercise. This development of robust and versatile R2R gravure printed electrodes represents a key translational step in enabling large-scale, low-cost fabrication of disposable wearable sensors for personalized health monitoring applications.

Coherent fiber supercontinuum for biophotonics

PubMed Central

Tu, Haohua; Boppart, Stephen A.

2013-01-01

Biophotonics and nonlinear fiber optics have traditionally been two independent fields. Since the discovery of fiber-based supercontinuum generation in 1999, biophotonics applications employing incoherent light have experienced a large impact from nonlinear fiber optics, primarily because of the access to a wide range of wavelengths and a uniform spatial profile afforded by fiber supercontinuum. However, biophotonics applications employing coherent light have not benefited from the most well-known techniques of supercontinuum generation for reasons such as poor coherence (or high noise), insufficient controllability, and inadequate portability. Fortunately, a few key techniques involving nonlinear fiber optics and femtosecond laser development have emerged to overcome these critical limitations. Despite their relative independence, these techniques are the focus of this review, because they can be integrated into a low-cost portable biophotonics source platform. This platform can be shared across many different areas of research in biophotonics, enabling new applications such as point-of-care coherent optical biomedical imaging. PMID:24358056

An exploration of the enablers and barriers in access to the Dutch healthcare system among Ghanaians in Amsterdam

PubMed Central

2012-01-01

Background Sub-Saharan African populations are growing in many European countries. Data on the health of these populations are rare. Additionally, many sub-Saharan African migrants are confronted with issues of low socio-economic status, acculturation and language difficulties, which may hamper their access to health care. Despite the identification of some of those barriers, little is known about the enabling factors. Knowledge about the enablers and barriers in access to healthcare experienced is important in addressing their health needs and promoting healthcare access. This study aimed to investigate the enabling factors as well as barriers in access to the Dutch healthcare system among the largest sub-Saharan African migrant group (Ghanaians) living in Amsterdam, the Netherlands. Methods Six focus groups were conducted from November 2009 to February 2010. A semi-structured interview guideline was used. Discussions were conducted in English or Twi (Ghanaian dialect), recorded and transcribed verbatim. Analysis was based on the Andersen model of healthcare utilisation using MAXQDA software. Results Knowledge and perceived quality of the health system, awareness of diseases, family and community support, community initiatives and availability of social support were the main enablers to the healthcare system. Difficulties with the Dutch language and mistrust in health care providers were major barriers in access to healthcare. Conclusions Access to healthcare is facilitated mainly by knowledge of and the perceived efficiency and quality of the Dutch healthcare system. However, poor Dutch language proficiency and mistrust in health care providers appear to be important barriers in accessing healthcare. The enablers and barriers identified by this study provide useful information for promoting healthcare access among this and similar Sub-Saharan African communities. PMID:22443162

An exploration of the enablers and barriers in access to the Dutch healthcare system among Ghanaians in Amsterdam.

PubMed

Boateng, Linda; Nicolaou, Mary; Dijkshoorn, Henriëtte; Stronks, Karien; Agyemang, Charles

2012-03-24

Sub-Saharan African populations are growing in many European countries. Data on the health of these populations are rare. Additionally, many sub-Saharan African migrants are confronted with issues of low socio-economic status, acculturation and language difficulties, which may hamper their access to health care. Despite the identification of some of those barriers, little is known about the enabling factors. Knowledge about the enablers and barriers in access to healthcare experienced is important in addressing their health needs and promoting healthcare access. This study aimed to investigate the enabling factors as well as barriers in access to the Dutch healthcare system among the largest sub-Saharan African migrant group (Ghanaians) living in Amsterdam, the Netherlands. Six focus groups were conducted from November 2009 to February 2010. A semi-structured interview guideline was used. Discussions were conducted in English or Twi (Ghanaian dialect), recorded and transcribed verbatim. Analysis was based on the Andersen model of healthcare utilisation using MAXQDA software. Knowledge and perceived quality of the health system, awareness of diseases, family and community support, community initiatives and availability of social support were the main enablers to the healthcare system. Difficulties with the Dutch language and mistrust in health care providers were major barriers in access to healthcare. Access to healthcare is facilitated mainly by knowledge of and the perceived efficiency and quality of the Dutch healthcare system. However, poor Dutch language proficiency and mistrust in health care providers appear to be important barriers in accessing healthcare. The enablers and barriers identified by this study provide useful information for promoting healthcare access among this and similar Sub-Saharan African communities.

Scanner focus metrology and control system for advanced 10nm logic node

NASA Astrophysics Data System (ADS)

Oh, Junghun; Maeng, Kwang-Seok; Shin, Jae-Hyung; Choi, Won-Woong; Won, Sung-Keun; Grouwstra, Cedric; El Kodadi, Mohamed; Heil, Stephan; van der Meijden, Vidar; Hong, Jong Kyun; Kim, Sang-Jin; Kwon, Oh-Sung

2018-03-01

Immersion lithography is being extended beyond the 10-nm node and the lithography performance requirement needs to be tightened further to ensure good yield. Amongst others, good on-product focus control with accurate and dense metrology measurements is essential to enable this. In this paper, we will present new solutions that enable onproduct focus monitoring and control (mean and uniformity) suitable for high volume manufacturing environment. We will introduce the concept of pure focus and its role in focus control through the imaging optimizer scanner correction interface. The results will show that the focus uniformity can be improved by up to 25%.

47 CFR 32.5082 - Switched access revenue.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 2 2011-10-01 2011-10-01 false Switched access revenue. 32.5082 Section 32.5082 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES UNIFORM SYSTEM OF ACCOUNTS FOR TELECOMMUNICATIONS COMPANIES Instructions For Revenue Accounts § 32.5082 Switched...

47 CFR 32.5082 - Switched access revenue.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 2 2014-10-01 2014-10-01 false Switched access revenue. 32.5082 Section 32.5082 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES UNIFORM SYSTEM OF ACCOUNTS FOR TELECOMMUNICATIONS COMPANIES Instructions For Revenue Accounts § 32.5082 Switched...

The Uniform Migrant Student Record Transfer System. A Position Paper.

ERIC Educational Resources Information Center

National Committee on the Education of Migrant Children, New York, NY.

Initiated in the mid-sixties under Title I of the Elementary and Secondary Education Act, the Uniform Migrant Student Record Transfer System (UMSRTS) was designed to maintain ready accessibility via computer data base to the health and academic records of migrant children. The National Committee on the Education of Migrant Children (NCEMC)…

22 CFR 142.17 - New construction.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Relations DEPARTMENT OF STATE CIVIL RIGHTS NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR... accessible to and usable by persons with handicaps, if the construction was commenced after the effective... with handicaps. (c) Conformance with Uniform Federal Accessibility Standards. (1) Effective as of...

22 CFR 142.17 - New construction.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Relations DEPARTMENT OF STATE CIVIL RIGHTS NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR... accessible to and usable by persons with handicaps, if the construction was commenced after the effective... with handicaps. (c) Conformance with Uniform Federal Accessibility Standards. (1) Effective as of...

22 CFR 142.17 - New construction.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Relations DEPARTMENT OF STATE CIVIL RIGHTS NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR... accessible to and usable by persons with handicaps, if the construction was commenced after the effective... with handicaps. (c) Conformance with Uniform Federal Accessibility Standards. (1) Effective as of...

47 CFR 32.5083 - Special access revenue.

Code of Federal Regulations, 2010 CFR

2010-10-01

.... (a) This account shall include all federally and state tariffed charges assessed for other than end user or switched access charges referred to in Account 5081, End user revenue, and Account 5082... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES UNIFORM SYSTEM OF ACCOUNTS...

Remote Access to Wireless Communications Systems Laboratory--New Technology Approach

ERIC Educational Resources Information Center

Kafadarova, Nadezhda; Sotirov, Sotir; Milev, Mihail

2012-01-01

Technology nowadays enables the remote access to laboratory equipment and instruments via Internet. This is especially useful in engineering education, where students can conduct laboratory experiment remotely. Such remote laboratory access can enable students to use expensive laboratory equipment, which is not usually available to students. In…

Universal Index System

NASA Technical Reports Server (NTRS)

Kelley, Steve; Roussopoulos, Nick; Sellis, Timos; Wallace, Sarah

1993-01-01

The Universal Index System (UIS) is an index management system that uses a uniform interface to solve the heterogeneity problem among database management systems. UIS provides an easy-to-use common interface to access all underlying data, but also allows different underlying database management systems, storage representations, and access methods.

20 CFR 435.53 - Retention and access requirements for records.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Retention and access requirements for records. 435.53 Section 435.53 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, OTHER NON-PROFIT...

78 FR 19979 - Establishment of the Presidential Commission on Election Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-03

..., recruitment, and number of poll workers; (iii) voting accessibility for uniformed and overseas voters; (iv) the efficient management of voter rolls and poll books; (v) voting machine capacity and technology; (vi) ballot simplicity and voter education; (vii) voting accessibility for individuals with...

20 CFR 437.42 - Retention and access requirements for records.

Code of Federal Regulations, 2010 CFR

2010-04-01

.... 437.42 Section 437.42 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE... (c) of this section. (2) If any litigation, claim, negotiation, audit or other action involving the... to make audits, examinations, excerpts, and transcripts. (2) Expiration of right of access. The...

20 CFR 437.42 - Retention and access requirements for records.

Code of Federal Regulations, 2011 CFR

2011-04-01

.... 437.42 Section 437.42 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE... (c) of this section. (2) If any litigation, claim, negotiation, audit or other action involving the... to make audits, examinations, excerpts, and transcripts. (2) Expiration of right of access. The...

Highly uniform parallel microfabrication using a large numerical aperture system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Zi-Yu; Su, Ya-Hui, E-mail: ustcsyh@ahu.edu.cn, E-mail: dongwu@ustc.edu.cn; Zhang, Chen-Chu

In this letter, we report an improved algorithm to produce accurate phase patterns for generating highly uniform diffraction-limited multifocal arrays in a large numerical aperture objective system. It is shown that based on the original diffraction integral, the uniformity of the diffraction-limited focal arrays can be improved from ∼75% to >97%, owing to the critical consideration of the aperture function and apodization effect associated with a large numerical aperture objective. The experimental results, e.g., 3 × 3 arrays of square and triangle, seven microlens arrays with high uniformity, further verify the advantage of the improved algorithm. This algorithm enables the laser parallelmore » processing technology to realize uniform microstructures and functional devices in the microfabrication system with a large numerical aperture objective.« less

Developing Guidelines for Evaluating the Adaptation of Accessible Web-Based Learning Materials

ERIC Educational Resources Information Center

Radovan, Marko; Perdih, Mojca

2016-01-01

E-learning is a rapidly developing form of education. One of the key characteristics of e-learning is flexibility, which enables easier access to knowledge for everyone. Information and communications technology (ICT), which is e-learning's main component, enables alternative means of accessing the web-based learning materials that comprise the…

Remote Access Laboratories in Australia and Europe

ERIC Educational Resources Information Center

Ku, H.; Ahfock, T.; Yusaf, T.

2011-01-01

Remote access laboratories (RALs) were first developed in 1994 in Australia and Switzerland. The main purposes of developing them are to enable students to do their experiments at their own pace, time and locations and to enable students and teaching staff to get access to facilities beyond their institutions. Currently, most of the experiments…

Integrated radiologist's workstation enabling the radiologist as an effective clinical consultant

NASA Astrophysics Data System (ADS)

McEnery, Kevin W.; Suitor, Charles T.; Hildebrand, Stan; Downs, Rebecca; Thompson, Stephen K.; Shepard, S. Jeff

2002-05-01

Since February 2000, radiologists at the M. D. Anderson Cancer Center have accessed clinical information through an internally developed radiologist's clinical interpretation workstation called RadStation. This project provides a fully integrated digital dictation workstation with clinical data review. RadStation enables the radiologist as an effective clinical consultant with access to pertinent sources of clinical information at the time of dictation. Data sources not only include prior radiology reports from the radiology information system (RIS) but access to pathology data, laboratory data, history and physicals, clinic notes, and operative reports. With integrated clinical information access, a radiologists's interpretation not only comments on morphologic findings but also can enable evaluation of study findings in the context of pertinent clinical presentation and history. Image access is enabled through the integration of an enterprise image archive (Stentor, San Francisco). Database integration is achieved by a combination of real time HL7 messaging and queries to SQL-based legacy databases. A three-tier system architecture accommodates expanding access to additional databases including real-time patient schedule as well as patient medications and allergies.

Enabling Tools and Methods for International, Inter-disciplinary and Educational Collaboration

NASA Astrophysics Data System (ADS)

Robinson, E. M.; Hoijarvi, K.; Falke, S.; Fialkowski, E.; Kieffer, M.; Husar, R. B.

2008-05-01

In the past, collaboration has taken place in tightly-knit workgroups where the members had direct connections to each other. Such collaboration was confined to small workgroups and person-to-person communication. Recent developments through the Internet foster virtual workgroups and organizations where dynamic, 'just-in-time' collaboration can take place over a much larger scale. The emergence of virtual workgroups has strongly influenced the interaction of inter-national, inter-disciplinary, as well as educational activities. In this paper we present an array of enabling tools and methods that incorporate the new technologies including web services, software mashups, tag-based structuring and searching, and wikis for collaborative writing and content organization. Large monolithic, 'do-it-all' software tools are giving way to web service modules, combined through service chaining. Application software can now be created using Service Oriented Architecture (SOA). In the air quality community, data providers and users are distributed in space and time creating barriers for data access. By exposing the data on the internet the space, time barriers are lessened. The federated data system, DataFed, developed at Washington University, accesses data from autonomous, distributed providers. Through data "wrappers", DataFed provides uniform and standards-based access services to heterogeneous, distributed data. Service orientation not only lowers the entry resistance for service providers, but it also allows the creation of user-defined applications and/or mashups. For example, Google Earth's open API allowed many groups to mash their content with Google Earth. Ad hoc tagging gives a rich description of the internet resources, but it has the disadvantage of providing a fuzzy schema. The semantic uniformity of the internet resources can be improved by controlled tagging which apply a consistent namespace and tag combinations to diverse objects. One example of this is the photo-sharing web application Flickr. Just like data, by exposing photos through the internet those can be reused in ways unknown and unanticipated by the provider. For air quality application, Flickr allowed a rich collection of images of forest fire smoke, wind blown dust and haze events to be tagged with controlled tags and used in for evaluating subtle features of the events. Wikis, originally used just for collaboratively writing and discuss documents, are now also a social software workflow managers. In air quality data, wikis provides the means to collaboratively create rich metadata. Wikis become a virtual meeting place to discuss ideas before a workshop of conference, display tagged internet resources, and collaboratively work on documents. Wikis are also useful in the classroom. For instance in class projects, the wiki displays harvested resources, maintains collaborative documents and discussions and is the organizational memory for the project.

45 CFR 1183.42 - Retention and access requirements for records.

Code of Federal Regulations, 2010 CFR

2010-10-01

... FOUNDATION ON THE ARTS AND THE HUMANITIES INSTITUTE OF MUSEUM AND LIBRARY SERVICES UNIFORM ADMINISTRATIVE... (c) of this section. (2) If any litigation, claim, negotiation, audit or other action involving the... to make audits, examinations, excerpts, and transcripts. (2) Expiration of right of access. The...

45 CFR 1157.42 - Retention and access requirements for records.

Code of Federal Regulations, 2010 CFR

2010-10-01

... FOUNDATION ON THE ARTS AND THE HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS UNIFORM ADMINISTRATIVE REQUIREMENTS... (c) of this section. (2) If any litigation, claim, negotiation, audit or other action involving the... to make audits, examinations, excerpts, and transcripts. (2) Expiration of right of access. The...

45 CFR 1174.42 - Retention and access requirements for records.

Code of Federal Regulations, 2010 CFR

2010-10-01

... FOUNDATION ON THE ARTS AND THE HUMANITIES NATIONAL ENDOWMENT FOR THE HUMANITIES UNIFORM ADMINISTRATIVE... (c) of this section. (2) If any litigation, claim, negotiation, audit or other action involving the... to make audits, examinations, excerpts, and transcripts. (2) Expiration of right of access. The...

7 CFR 3016.42 - Retention and access requirements for records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Retention and access requirements for records. 3016.42 Section 3016.42 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF AGRICULTURE UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND...

Computer Security Systems Enable Access.

ERIC Educational Resources Information Center

Riggen, Gary

1989-01-01

A good security system enables access and protects information from damage or tampering, but the most important aspects of a security system aren't technical. A security procedures manual addresses the human element of computer security. (MLW)

Open Access Enabling Courses: Risking Academic Standards or Meeting Equity Aspirations

ERIC Educational Resources Information Center

Shah, Mahsood; Whannell, Robert

2017-01-01

Open access enabling courses have experienced growth in Australia. The growth is evidenced in student enrolments and the number of public and private institutions offering such courses. Traditionally these courses have provided a second chance to many students from various equity groups who have been unable to access tertiary education due to poor…

Using Learning Analytics to Assess Student Engagement and Academic Outcomes in Open Access Enabling Programmes

ERIC Educational Resources Information Center

Atherton, Mirella; Shah, Mahsood; Vazquez, Jenny; Griffiths, Zoe; Jackson, Brian; Burgess, Catherine

2017-01-01

Curriculum design, teaching methods, assessments and range of academic support need to be inclusive in Open Access Enabling courses. The findings of this study confirm a correlation between student access to online learning materials and a positive impact on grades in science courses. More specifically, students who frequently use the online…

What's Next for NASA? Life After the Shuttle Program

NASA Technical Reports Server (NTRS)

MacLaughlin, Mary; Petro, Janet E.

2012-01-01

KSC is the world's preeminent launch complex for government and commercial space access, enabling the world to explore and work in space. KSC safely manages, develops, integrates, and sustains space systems through partnerships that enable innovative, diverse access to space and inspires the Nation's future explorers capabilities to make accessing space less costly and more routine.

Knowledge and practice related to gestational diabetes among primary health care providers in Morocco: Potential for a defragmentation of care?

PubMed

Utz, Bettina; Assarag, Bouchra; Essolbi, Amina; Barkat, Amina; Delamou, Alexandre; De Brouwere, Vincent

2017-08-01

The objective of this study was to assess knowledge and practices of general practitioners, nurses and midwives working at primary health care facilities in Morocco regarding screening and management of gestational diabetes (GDM). Structured interviews with 100 doctors, midwives and nurses at 44 randomly selected public health care centers were conducted in Marrakech and Al Haouz. All data were descriptively analyzed. Ethical approval for the study was granted by the institutional review boards in Belgium and Morocco. Public primary health care providers have a basic understanding of gestational diabetes but screening and management practices are not uniform. Although 56.8% of the doctors had some pre-service training on gestational diabetes, most nurses and midwives lack such training. After diagnosing GDM, 88.5% of providers refer patients to specialists, only 11.5% treat them as outpatients. Updating knowledge and skills of providers through both pre- and in-service-training needs to be supported by uniform national standards enabling first line health care workers to manage women with GDM and thus increase access and provide a continuity in care. Findings of this study will be used to pilot a model of GDM screening and initial management through the primary level of care. Copyright © 2017 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Telepharmacy: a pharmacist’s perspective on the clinical benefits and challenges

PubMed Central

Poudel, Arjun; Nissen, Lisa M

2016-01-01

The use of information and telecommunication technologies has expanded at a rapid rate, which has a strong influence on healthcare delivery in many countries. Rural residents and communities, however, often lack easy access to healthcare services due to geographical and demographical factors. Telepharmacy, a more recent concept that refers to pharmaceutical service provision, enables healthcare services, such as medication review, patients counseling, and prescription verification, by a qualified pharmacist for the patients located at a distance from a remotely located hospital, pharmacy, or healthcare center. Telepharmacy has many recognizable benefits such as the easy access to healthcare services in remote and rural locations, economic benefits, patient satisfaction as a result of medication access and information in rural areas, effective patient counseling, and minimal scarcity of local pharmacist and pharmacy services. Telepharmacy undoubtedly is a great concept, but it is sometimes challenging to put into practice. Inherent to the adoption of these practices are legal challenges and pitfalls that need to be addressed. The start-up of telepharmacy (hardware, software, connectivity, and operational cost) involves considerable time, effort, and money. For rural hospitals with fewer patients, the issue of costs appears to be one of the biggest barriers to telepharmacy services. Moreover, execution and implementation of comprehensive and uniform telepharmacy law is still a challenge. A well-developed system, however, can change the practice of pharmacy that is beneficial to both the rural communities and the hospitals or retail pharmacies that deliver these services. PMID:29354542

The Mission Accessible Near-Earth Objects Survey (MANOS): spectroscopy results

NASA Astrophysics Data System (ADS)

Thomas, Cristina A.; Moskovitz, Nicholas; Hinkle, Mary L.; Mommert, Michael; Polishook, David; Thirouin, Audrey; Binzel, Richard; Christensen, Eric J.; DeMeo, Francesca E.; Person, Michael J.; Trilling, David E.; Willman, Mark; Burt, Brian

2016-10-01

The Mission Accessible Near-Earth Object Survey (MANOS) is an ongoing physical characterization survey to build a large, uniform catalog of physical properties including lightcurves and visible wavelength spectroscopy. We will use this catalog to investigate the global properties of the small NEO population and identify individual objects that can be targets of interest for future exploration. To accomplish our goals, MANOS uses a wide variety of telescopes (1-8m) in both the northern and southern hemispheres. We focus on targets that have been recently discovered and operate on a regular cadence of remote and queue observations to enable rapid characterization of small NEOs. Targets for MANOS are selected based on three criteria: mission accessibility, size, and observability. With our resources, we observe 5-10 newly discovered sub-km NEOs per month. MANOS has been operating for three years and we have observed over 500 near-Earth objects in that time.We will present results from the spectroscopy component of the MANOS program. Visible wavelength spectra are obtained using DeVeny on the Discovery Channel Telescope (DCT), Goodman on the Southern Astrophysical Research (SOAR) telescope, and GMOS on Gemini North and South. Over 300 NEO spectra have been obtained during our program. We will present preliminary results from our spectral sample. We will discuss the compositional diversity of the small NEO population and how the observed NEOs compare to the meteorite population.MANOS is funded by the NASA Near-Earth Object Observations program.

International Charter of principles for sharing bio-specimens and data.

PubMed

Mascalzoni, Deborah; Dove, Edward S; Rubinstein, Yaffa; Dawkins, Hugh J S; Kole, Anna; McCormack, Pauline; Woods, Simon; Riess, Olaf; Schaefer, Franz; Lochmüller, Hanns; Knoppers, Bartha M; Hansson, Mats

2015-06-01

There is a growing international agreement on the need to provide greater access to research data and bio-specimen collections to optimize their long-term value and exploit their potential for health discovery and validation. This is especially evident for rare disease research. Currently, the rising value of data and bio-specimen collections does not correspond with an equal increase in data/sample-sharing and data/sample access. Contradictory legal and ethical frameworks across national borders are obstacles to effective sharing: more specifically, the absence of an integrated model proves to be a major logistical obstruction. The Charter intends to amend the obstacle by providing both the ethical foundations on which data sharing should be based, as well as a general Material and Data Transfer Agreement (MTA/DTA). This Charter is the result of a careful negotiation of different stakeholders' interest and is built on earlier consensus documents and position statements, which provided the general international legal framework. Further to this, the Charter provides tools that may help accelerate sharing. The Charter has been formulated to serve as an enabling tool for effective and transparent data and bio-specimen sharing and the general MTA/DTA constitutes a mechanism to ensure uniformity of access across projects and countries, and may be regarded as a consistent basic agreement for addressing data and material sharing globally. The Charter is forward looking in terms of emerging issues from the perspective of a multi-stakeholder group, and where possible, provides strategies that may address these issues.

Job Opportunities Glitter for Librarians Who Surf the Net.

ERIC Educational Resources Information Center

Azar, A. Paula

1996-01-01

The Internet gives library professionals access to job opportunities that are not readily accessible in print. Employers can advertise at minimal cost and reach a broad, technically adept audience. This article lists Internet job resource sites and listservs for library and information professionals, providing Uniform Resource Locators (URLs),…

Infrared sensors for Earth observation missions

NASA Astrophysics Data System (ADS)

Ashcroft, P.; Thorne, P.; Weller, H.; Baker, I.

2007-10-01

SELEX S&AS is developing a family of infrared sensors for earth observation missions. The spectral bands cover shortwave infrared (SWIR) channels from around 1μm to long-wave infrared (LWIR) channels up to 15μm. Our mercury cadmium telluride (MCT) technology has enabled a sensor array design that can satisfy the requirements of all of the SWIR and medium-wave infrared (MWIR) bands with near-identical arrays. This is made possible by the combination of a set of existing technologies that together enable a high degree of flexibility in the pixel geometry, sensitivity, and photocurrent integration capacity. The solution employs a photodiode array under the control of a readout integrated circuit (ROIC). The ROIC allows flexible geometries and in-pixel redundancy to maximise operability and reliability, by combining the photocurrent from a number of photodiodes into a single pixel. Defective or inoperable diodes (or "sub-pixels") can be deselected with tolerable impact on the overall pixel performance. The arrays will be fabricated using the "loophole" process in MCT grown by liquid-phase epitaxy (LPE). These arrays are inherently robust, offer high quantum efficiencies and have been used in previous space programs. The use of loophole arrays also offers access to SELEX's avalanche photodiode (APD) technology, allowing low-noise, highly uniform gain at the pixel level where photon flux is very low.

Impact of AlO x layer on resistive switching characteristics and device-to-device uniformity of bilayered HfO x -based resistive random access memory devices

NASA Astrophysics Data System (ADS)

Chuang, Kai-Chi; Chung, Hao-Tung; Chu, Chi-Yan; Luo, Jun-Dao; Li, Wei-Shuo; Li, Yi-Shao; Cheng, Huang-Chung

2018-06-01

An AlO x layer was deposited on HfO x , and bilayered dielectric films were found to confine the formation locations of conductive filaments (CFs) during the forming process and then improve device-to-device uniformity. In addition, the Ti interposing layer was also adopted to facilitate the formation of oxygen vacancies. As a result, the resistive random access memory (RRAM) device with TiN/Ti/AlO x (1 nm)/HfO x (6 nm)/TiN stack layers demonstrated excellent device-to-device uniformity although it achieved slightly larger resistive switching characteristics, which were forming voltage (V Forming) of 2.08 V, set voltage (V Set) of 1.96 V, and reset voltage (V Reset) of ‑1.02 V, than the device with TiN/Ti/HfO x (6 nm)/TiN stack layers. However, the device with a thicker 2-nm-thick AlO x layer showed worse uniformity than the 1-nm-thick one. It was attributed to the increased oxygen atomic percentage in the bilayered dielectric films of the 2-nm-thick one. The difference in oxygen content showed that there would be less oxygen vacancies to form CFs. Therefore, the random growth of CFs would become severe and the device-to-device uniformity would degrade.

oGNM: online computation of structural dynamics using the Gaussian Network Model

PubMed Central

Yang, Lee-Wei; Rader, A. J.; Liu, Xiong; Jursa, Cristopher Jon; Chen, Shann Ching; Karimi, Hassan A.; Bahar, Ivet

2006-01-01

An assessment of the equilibrium dynamics of biomolecular systems, and in particular their most cooperative fluctuations accessible under native state conditions, is a first step towards understanding molecular mechanisms relevant to biological function. We present a web-based system, oGNM that enables users to calculate online the shape and dispersion of normal modes of motion for proteins, oligonucleotides and their complexes, or associated biological units, using the Gaussian Network Model (GNM). Computations with the new engine are 5–6 orders of magnitude faster than those using conventional normal mode analyses. Two cases studies illustrate the utility of oGNM. The first shows that the thermal fluctuations predicted for 1250 non-homologous proteins correlate well with X-ray crystallographic data over a broad range [7.3–15 Å] of inter-residue interaction cutoff distances and the correlations improve with increasing observation temperatures. The second study, focused on 64 oligonucleotides and oligonucleotide–protein complexes, shows that good agreement with experiments is achieved by representing each nucleotide by three GNM nodes (as opposed to one-node-per-residue in proteins) along with uniform interaction ranges for all components of the complexes. These results open the way to a rapid assessment of the dynamics of DNA/RNA-containing complexes. The server can be accessed at . PMID:16845002

Cloud-Enabled Climate Analytics-as-a-Service using Reanalysis data: A case study.

NASA Astrophysics Data System (ADS)

Nadeau, D.; Duffy, D.; Schnase, J. L.; McInerney, M.; Tamkin, G.; Potter, G. L.; Thompson, J. H.

2014-12-01

The NASA Center for Climate Simulation (NCCS) maintains advanced data capabilities and facilities that allow researchers to access the enormous volume of data generated by weather and climate models. The NASA Climate Model Data Service (CDS) and the NCCS are merging their efforts to provide Climate Analytics-as-a-Service for the comparative study of the major reanalysis projects: ECMWF ERA-Interim, NASA/GMAO MERRA, NOAA/NCEP CFSR, NOAA/ESRL 20CR, JMA JRA25, and JRA55. These reanalyses have been repackaged to netCDF4 file format following the CMIP5 Climate and Forecast (CF) metadata convention prior to be sequenced into the Hadoop Distributed File System ( HDFS ). A small set of operations that represent a common starting point in many analysis workflows was then created: min, max, sum, count, variance and average. In this example, Reanalysis data exploration was performed with the use of Hadoop MapReduce and accessibility was achieved using the Climate Data Service(CDS) application programming interface (API) created at NCCS. This API provides a uniform treatment of large amount of data. In this case study, we have limited our exploration to 2 variables, temperature and precipitation, using 3 operations, min, max and avg and using 30-year of Reanalysis data for 3 regions of the world: global, polar, subtropical.

SiteDB: Marshalling people and resources available to CMS

NASA Astrophysics Data System (ADS)

Metson, S.; Bonacorsi, D.; Dias Ferreira, M.; Egeland, R.

2010-04-01

In a collaboration the size of CMS (approx. 3000 users, and almost 100 computing centres of varying size) communication and accurate information about the sites it has access to is vital in co-ordinating the multitude of computing tasks required for smooth running. SiteDB is a tool developed by CMS to track sites available to the collaboration, the allocation to CMS of resources available at those sites and the associations between CMS members and the sites (as either a manager/operator of the site or a member of a group associated to the site). It is used to track the roles a person has for an associated site or group. SiteDB eases the coordination load for the operations teams by providing a consistent interface to manage communication with the people working at a site, by identifying who is responsible for a given task or service at a site and by offering a uniform interface to information on CMS contacts and sites. SiteDB provides api's and reports for other CMS tools to use to access the information it contains, for instance enabling CRAB to use "user friendly" names when black/white listing CE's, providing role based authentication and authorisation for other web based services and populating various troubleshooting squads in external ticketing systems in use daily by CMS Computing operations.

Interacting with the National Database for Autism Research (NDAR) via the LONI Pipeline workflow environment.

PubMed

Torgerson, Carinna M; Quinn, Catherine; Dinov, Ivo; Liu, Zhizhong; Petrosyan, Petros; Pelphrey, Kevin; Haselgrove, Christian; Kennedy, David N; Toga, Arthur W; Van Horn, John Darrell

2015-03-01

Under the umbrella of the National Database for Clinical Trials (NDCT) related to mental illnesses, the National Database for Autism Research (NDAR) seeks to gather, curate, and make openly available neuroimaging data from NIH-funded studies of autism spectrum disorder (ASD). NDAR has recently made its database accessible through the LONI Pipeline workflow design and execution environment to enable large-scale analyses of cortical architecture and function via local, cluster, or "cloud"-based computing resources. This presents a unique opportunity to overcome many of the customary limitations to fostering biomedical neuroimaging as a science of discovery. Providing open access to primary neuroimaging data, workflow methods, and high-performance computing will increase uniformity in data collection protocols, encourage greater reliability of published data, results replication, and broaden the range of researchers now able to perform larger studies than ever before. To illustrate the use of NDAR and LONI Pipeline for performing several commonly performed neuroimaging processing steps and analyses, this paper presents example workflows useful for ASD neuroimaging researchers seeking to begin using this valuable combination of online data and computational resources. We discuss the utility of such database and workflow processing interactivity as a motivation for the sharing of additional primary data in ASD research and elsewhere.

Recent improvements in the NASA technical report server

NASA Technical Reports Server (NTRS)

Maa, Ming-Hokng; Nelson, Michael L.

1995-01-01

The NASA Technical Report Server (NTRS), a World Wide Web (WWW) report distribution service, has been modified to allow parallel database queries, significantly decreasing user access time by an average factor of 2.3, access from clients behind firewalls and/or proxies which truncate excessively long Uniform Resource Locators (URL's), access to non-Wide Area Information Server (WAIS) databases, and compatibility with the Z39-50.3 protocol.

High efficiency III-nitride light-emitting diodes

DOEpatents

Crawford, Mary; Koleske, Daniel; Cho, Jaehee; Zhu, Di; Noemaun, Ahmed; Schubert, Martin F; Schubert, E. Fred

2013-05-28

Tailored doping of barrier layers enables balancing of the radiative recombination among the multiple-quantum-wells in III-Nitride light-emitting diodes. This tailored doping enables more symmetric carrier transport and uniform carrier distribution which help to reduce electron leakage and thus reduce the efficiency droop in high-power III-Nitride LEDs. Mitigation of the efficiency droop in III-Nitride LEDs may enable the pervasive market penetration of solid-state-lighting technologies in high-power lighting and illumination.

A Smart Cage With Uniform Wireless Power Distribution in 3D for Enabling Long-Term Experiments With Freely Moving Animals.

PubMed

Mirbozorgi, S Abdollah; Bahrami, Hadi; Sawan, Mohamad; Gosselin, Benoit

2016-04-01

This paper presents a novel experimental chamber with uniform wireless power distribution in 3D for enabling long-term biomedical experiments with small freely moving animal subjects. The implemented power transmission chamber prototype is based on arrays of parallel resonators and multicoil inductive links, to form a novel and highly efficient wireless power transmission system. The power transmitter unit includes several identical resonators enclosed in a scalable array of overlapping square coils which are connected in parallel to provide uniform power distribution along x and y. Moreover, the proposed chamber uses two arrays of primary resonators, facing each other, and connected in parallel to achieve uniform power distribution along the z axis. Each surface includes 9 overlapped coils connected in parallel and implemented into two layers of FR4 printed circuit board. The chamber features a natural power localization mechanism, which simplifies its implementation and ease its operation by avoiding the need for active detection and control mechanisms. A single power surface based on the proposed approach can provide a power transfer efficiency (PTE) of 69% and a power delivered to the load (PDL) of 120 mW, for a separation distance of 4 cm, whereas the complete chamber prototype provides a uniform PTE of 59% and a PDL of 100 mW in 3D, everywhere inside the chamber with a size of 27×27×16 cm(3).

A new pulsed laser deposition technique: scanning multi-component pulsed laser deposition method.

PubMed

Fischer, D; de la Fuente, G F; Jansen, M

2012-04-01

The scanning multi-component pulsed laser deposition (PLD) method realizes uniform depositions of desired coatings by a modified pulsed laser deposition process, preferably with a femto-second laser-system. Multi-component coatings (single or multilayered) are thus deposited onto substrates via laser induced ablation of segmented targets. This is achieved via horizontal line-scanning of a focused laser beam over a uniformly moving target's surface. This process allows to deposit the desired composition of the coating simultaneously, starting from the different segments of the target and adjusting the scan line as a function of target geometry. The sequence and thickness of multilayers can easily be adjusted by target architecture and motion, enabling inter/intra layer concentration gradients and thus functional gradient coatings. This new, simple PLD method enables the achievement of uniform, large-area coatings. Case studies were performed with segmented targets containing aluminum, titanium, and niobium. Under the laser irradiation conditions applied, all three metals were uniformly ablated. The elemental composition within the rough coatings obtained was fixed by the scanned area to Ti-Al-Nb = 1:1:1. Crystalline aluminum, titanium, and niobium were found to coexist side by side at room temperature within the substrate, without alloy formation up to 600 °C. © 2012 American Institute of Physics

Conformal Electroplating of Azobenzene-Based Solar Thermal Fuels onto Large-Area and Fiber Geometries.

PubMed

Zhitomirsky, David; Grossman, Jeffrey C

2016-10-05

There is tremendous growth in fields where small functional molecules and colloidal nanomaterials are integrated into thin films for solid-state device applications. Many of these materials are synthesized in solution and there often exists a significant barrier to transition them into the solid state in an efficient manner. Here, we develop a methodology employing an electrodepositable copolymer consisting of small functional molecules for applications in solar energy harvesting and storage. We employ azobenzene solar thermal fuel polymers and functionalize them to enable deposition from low concentration solutions in methanol, resulting in uniform and large-area thin films. This approach enables conformal deposition on a variety of conducting substrates that can be either flat or structured depending on the application. Our approach further enables control over film growth via electrodepsition conditions and results in highly uniform films of hundreds of nanometers to microns in thickness. We demonstrate that this method enables superior retention of solar thermal fuel properties, with energy densities of ∼90 J/g, chargeability in the solid state, and exceptional materials utilization compared to other solid-state processing approaches. This novel approach is applicable to systems such as photon upconversion, photovoltaics, photosensing, light emission, and beyond, where small functional molecules enable solid-state applications.

Approaches to Reducing Federal Spending on Military Health Care

DTIC Science & Technology

2014-01-01

medical school, the Uniformed Services University of the Health Sciences (USUHS), while expanding the number of scholarships provided to students... actuaries esti- 8. Department of Defense, Evaluation of the TRICARE Program— Access, Cost and Quality: Fiscal Year 2013 Report to Congress (February...DoD’s Uniformed Services University of the Health Sciences —would be closed. 4. See Congressional Budget Office, Lessons from Medicare’s Demonstration

Development of a 750x750 pixels CMOS imager sensor for tracking applications

NASA Astrophysics Data System (ADS)

Larnaudie, Franck; Guardiola, Nicolas; Saint-Pé, Olivier; Vignon, Bruno; Tulet, Michel; Davancens, Robert; Magnan, Pierre; Corbière, Franck; Martin-Gonthier, Philippe; Estribeau, Magali

2017-11-01

Solid-state optical sensors are now commonly used in space applications (navigation cameras, astronomy imagers, tracking sensors...). Although the charge-coupled devices are still widely used, the CMOS image sensor (CIS), which performances are continuously improving, is a strong challenger for Guidance, Navigation and Control (GNC) systems. This paper describes a 750x750 pixels CMOS image sensor that has been specially designed and developed for star tracker and tracking sensor applications. Such detector, that is featuring smart architecture enabling very simple and powerful operations, is built using the AMIS 0.5μm CMOS technology. It contains 750x750 rectangular pixels with 20μm pitch. The geometry of the pixel sensitive zone is optimized for applications based on centroiding measurements. The main feature of this device is the on-chip control and timing function that makes the device operation easier by drastically reducing the number of clocks to be applied. This powerful function allows the user to operate the sensor with high flexibility: measurement of dark level from masked lines, direct access to the windows of interest… A temperature probe is also integrated within the CMOS chip allowing a very precise measurement through the video stream. A complete electro-optical characterization of the sensor has been performed. The major parameters have been evaluated: dark current and its uniformity, read-out noise, conversion gain, Fixed Pattern Noise, Photo Response Non Uniformity, quantum efficiency, Modulation Transfer Function, intra-pixel scanning. The characterization tests are detailed in the paper. Co60 and protons irradiation tests have been also carried out on the image sensor and the results are presented. The specific features of the 750x750 image sensor such as low power CMOS design (3.3V, power consumption<100mW), natural windowing (that allows efficient and robust tracking algorithms), simple proximity electronics (because of the on-chip control and timing function) enabling a high flexibility architecture, make this imager a good candidate for high performance tracking applications.

15 CFR 14.53 - Retention and access requirements for records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Retention and access requirements for records. 14.53 Section 14.53 Commerce and Foreign Trade Office of the Secretary of Commerce UNIFORM.... (e) The DoC, the Inspector General, Comptroller General of the United States, or any of their duly...

15 CFR 24.42 - Retention and access requirements for records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Retention and access requirements for records. 24.42 Section 24.42 Commerce and Foreign Trade Office of the Secretary of Commerce UNIFORM... computer usage chargeback rates or composite fringe benefit rates). (i) If submitted for negotiation. If...

17 CFR 259.602 - Form ID, uniform application for access codes to file on EDGAR.

Code of Federal Regulations, 2010 CFR

2010-04-01

...)—allows a filer, filing agent or training agent to log on to the EDGAR system, submit filings, and change... agent to change its Password. [69 FR 22710, Apr. 26, 2004] Editorial Note: For Federal Register... section of the printed volume and on GPO Access. ...

Breakthrough Science Enabled by Regular Access to Orbits Beyond Earth

NASA Astrophysics Data System (ADS)

Gorjian, V.

2018-02-01

Regular launches to the Deep Space Gateway (DSG) will enable smallsats to access orbits not currently easily available to low cost missions. These orbits will allow great new science, especially when using the DSG as an optical hub for downlink.

Solid-state semiconductors are better alternatives to arc-lamps for efficient and uniform illumination in minimal access surgery.

PubMed

Lee, Alex C H; Elson, Daniel S; Neil, Mark A; Kumar, Sunil; Ling, Bingo W; Bello, Fernando; Hanna, George B

2009-03-01

Current arc-lamp illumination systems have a number of technical and ergonomic limitations. White light-emitting diodes (LEDs) are energy-efficient solid-state lighting devices which are small, durable and inexpensive. Their use as an alternative to arc-lamp light sources in minimal access surgery has not been explored. This study aims to develop an LED-based endo-illuminator and to determine its lighting characteristics for use in minimal access surgery. We developed an LED endo-illuminator using a white LED mounted at the tip of a steel rod. Offline image analysis was carried out to compare the illuminated field using the LED endo-illuminator or an arc-lamp based endoscope in terms of uniformity, shadow sharpness and overall image intensity. Direct radiometric power measurements in light intensity and stability were obtained. Visual perception of fine details at the peripheral endoscopic field was assessed by 13 subjects using the different illumination systems. Illumination from the LED endo-illuminator was more uniform compared to illumination from an arc-lamp source, especially at the closer distance of 4 cm (0.0006 versus 0.0028 arbitrary units--lower value indicates more uniform illumination). The shadows were also sharper (edge widths of 16 versus 44 pixels for the first edge and 15 versus 61 pixels for the second edge). The overall mean image intensity was higher (127 versus 100 arbitrary units) when using the autoshutter mode despite the lower direct radiometric power, about one tenth of the arc-lamp endoscopic system. The illumination was also more stable with less flickering (0.02% versus 5% of total power in non-DC components). Higher median scores on visual perception was also obtained (237 versus 157, p < 0.001). The LED endo-illuminator provides more uniform illumination with sharper shadows, less flickering and better illumination for visual perception than the arc-lamp-based system currently used.

The health care and life sciences community profile for dataset descriptions

PubMed Central

Alexiev, Vladimir; Ansell, Peter; Bader, Gary; Baran, Joachim; Bolleman, Jerven T.; Callahan, Alison; Cruz-Toledo, José; Gaudet, Pascale; Gombocz, Erich A.; Gonzalez-Beltran, Alejandra N.; Groth, Paul; Haendel, Melissa; Ito, Maori; Jupp, Simon; Juty, Nick; Katayama, Toshiaki; Kobayashi, Norio; Krishnaswami, Kalpana; Laibe, Camille; Le Novère, Nicolas; Lin, Simon; Malone, James; Miller, Michael; Mungall, Christopher J.; Rietveld, Laurens; Wimalaratne, Sarala M.; Yamaguchi, Atsuko

2016-01-01

Access to consistent, high-quality metadata is critical to finding, understanding, and reusing scientific data. However, while there are many relevant vocabularies for the annotation of a dataset, none sufficiently captures all the necessary metadata. This prevents uniform indexing and querying of dataset repositories. Towards providing a practical guide for producing a high quality description of biomedical datasets, the W3C Semantic Web for Health Care and the Life Sciences Interest Group (HCLSIG) identified Resource Description Framework (RDF) vocabularies that could be used to specify common metadata elements and their value sets. The resulting guideline covers elements of description, identification, attribution, versioning, provenance, and content summarization. This guideline reuses existing vocabularies, and is intended to meet key functional requirements including indexing, discovery, exchange, query, and retrieval of datasets, thereby enabling the publication of FAIR data. The resulting metadata profile is generic and could be used by other domains with an interest in providing machine readable descriptions of versioned datasets. PMID:27602295

Objective Assessment of Surgical Technical Skill and Competency in the Operating Room.

PubMed

Vedula, S Swaroop; Ishii, Masaru; Hager, Gregory D

2017-06-21

Training skillful and competent surgeons is critical to ensure high quality of care and to minimize disparities in access to effective care. Traditional models to train surgeons are being challenged by rapid advances in technology, an intensified patient-safety culture, and a need for value-driven health systems. Simultaneously, technological developments are enabling capture and analysis of large amounts of complex surgical data. These developments are motivating a "surgical data science" approach to objective computer-aided technical skill evaluation (OCASE-T) for scalable, accurate assessment; individualized feedback; and automated coaching. We define the problem space for OCASE-T and summarize 45 publications representing recent research in this domain. We find that most studies on OCASE-T are simulation based; very few are in the operating room. The algorithms and validation methodologies used for OCASE-T are highly varied; there is no uniform consensus. Future research should emphasize competency assessment in the operating room, validation against patient outcomes, and effectiveness for surgical training.

Footprint Database and web services for the Herschel space observatory

NASA Astrophysics Data System (ADS)

Verebélyi, Erika; Dobos, László; Kiss, Csaba

2015-08-01

Using all telemetry and observational meta-data, we created a searchable database of Herschel observation footprints. Data from the Herschel space observatory is freely available for everyone but no uniformly processed catalog of all observations has been published yet. As a first step, we unified the data model for all three Herschel instruments in all observation modes and compiled a database of sky coverage information. As opposed to methods using a pixellation of the sphere, in our database, sky coverage is stored in exact geometric form allowing for precise area calculations. Indexing of the footprints allows for very fast search among observations based on pointing, time, sky coverage overlap and meta-data. This enables us, for example, to find moving objects easily in Herschel fields. The database is accessible via a web site and also as a set of REST web service functions which makes it usable from program clients like Python or IDL scripts. Data is available in various formats including Virtual Observatory standards.

Tuning the Fermi velocity in Dirac materials with an electric field.

PubMed

Díaz-Fernández, A; Chico, Leonor; González, J W; Domínguez-Adame, F

2017-08-14

Dirac materials are characterized by energy-momentum relations that resemble those of relativistic massless particles. Commonly denominated Dirac cones, these dispersion relations are considered to be their essential feature. These materials comprise quite diverse examples, such as graphene and topological insulators. Band-engineering techniques should aim to a full control of the parameter that characterizes the Dirac cones: the Fermi velocity. We propose a general mechanism that enables the fine-tuning of the Fermi velocity in Dirac materials in a readily accessible way for experiments. By embedding the sample in a uniform electric field, the Fermi velocity is substantially modified. We first prove this result analytically, for the surface states of a topological insulator/semiconductor interface, and postulate its universality in other Dirac materials. Then we check its correctness in carbon-based Dirac materials, namely graphene nanoribbons and nanotubes, thus showing the validity of our hypothesis in different Dirac systems by means of continuum, tight-binding and ab-initio calculations.

Parameter-free determination of the exchange constant in thin films using magnonic patterning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Langer, M.; Wagner, K.; Fassbender, J.

2016-03-07

An all-electrical method is presented to determine the exchange constant of magnetic thin films using ferromagnetic resonance. For films of 20 nm thickness and below, the determination of the exchange constant A, a fundamental magnetic quantity, is anything but straightforward. Among others, the most common methods are based on the characterization of perpendicular standing spin-waves. These approaches are however challenging, due to (i) very high energies and (ii) rather small intensities in this thickness regime. In the presented approach, surface patterning is applied to a permalloy (Ni{sub 80}Fe{sub 20}) film and a Co{sub 2}Fe{sub 0.4}Mn{sub 0.6}Si Heusler compound. Acting as amore » magnonic crystal, such structures enable the coupling of backward volume spin-waves to the uniform mode. Subsequent ferromagnetic resonance measurements give access to the spin-wave spectra free of unquantifiable parameters and, thus, to the exchange constant A with high accuracy.« less

Keep Up or Fall Behind

ERIC Educational Resources Information Center

Ramaswami, Rama

2007-01-01

In the race to enable information access and collaboration, institutions are taking advantage of new tools to drive content management innovation. New content management systems (CMS) features and functions are driving true innovation in content management, and enabling information access, sharing, collaboration, and tracking on a scale heretofore…

The Architecture of Access: A Grounded Theory on the Nature of Access to Early Childhood Services within a Children's Centre, Derived from Nine Parent Voices

ERIC Educational Resources Information Center

Hayward, Kate; Fletcher, Colin; Whalley, Margy; McKinnon, Eddie; Gallagher, Tracy; Prodger, Angela; Donoyou, Heather; Potts, Judy; Young, Elaine

2013-01-01

This was a collaborative action research study by lead staff, researchers and parents at the Pen Green Centre for Children and their Families in England. The study focuses on the factors enabling access to children's services by nine parents from challenging family contexts. The critical questions were: What enabled some parents to overcome…

Adaptive Code Division Multiple Access Protocol for Wireless Network-on-Chip Architectures

NASA Astrophysics Data System (ADS)

Vijayakumaran, Vineeth

Massive levels of integration following Moore's Law ushered in a paradigm shift in the way on-chip interconnections were designed. With higher and higher number of cores on the same die traditional bus based interconnections are no longer a scalable communication infrastructure. On-chip networks were proposed enabled a scalable plug-and-play mechanism for interconnecting hundreds of cores on the same chip. Wired interconnects between the cores in a traditional Network-on-Chip (NoC) system, becomes a bottleneck with increase in the number of cores thereby increasing the latency and energy to transmit signals over them. Hence, there has been many alternative emerging interconnect technologies proposed, namely, 3D, photonic and multi-band RF interconnects. Although they provide better connectivity, higher speed and higher bandwidth compared to wired interconnects; they also face challenges with heat dissipation and manufacturing difficulties. On-chip wireless interconnects is one other alternative proposed which doesn't need physical interconnection layout as data travels over the wireless medium. They are integrated into a hybrid NOC architecture consisting of both wired and wireless links, which provides higher bandwidth, lower latency, lesser area overhead and reduced energy dissipation in communication. However, as the bandwidth of the wireless channels is limited, an efficient media access control (MAC) scheme is required to enhance the utilization of the available bandwidth. This thesis proposes using a multiple access mechanism such as Code Division Multiple Access (CDMA) to enable multiple transmitter-receiver pairs to send data over the wireless channel simultaneously. It will be shown that such a hybrid wireless NoC with an efficient CDMA based MAC protocol can significantly increase the performance of the system while lowering the energy dissipation in data transfer. In this work it is shown that the wireless NoC with the proposed CDMA based MAC protocol outperformed the wired counterparts and several other wireless architectures proposed in literature in terms of bandwidth and packet energy dissipation. Significant gains were observed in packet energy dissipation and bandwidth even with scaling the system to higher number of cores. Non-uniform traffic simulations showed that the proposed CDMA-WiNoC was consistent in bandwidth across all traffic patterns. It is also shown that the CDMA based MAC scheme does not introduce additional reliability concerns in data transfer over the on-chip wireless interconnects.

Method for uniformly bending conduits

DOEpatents

Dekanich, S.J.

1984-04-27

The present invention is directed to a method for bending metal tubing through various radii while maintaining uniform cross section of the tubing. The present invention is practical by filling the tubing to a sufficient level with water, freezing the water to ice and bending the ice-filled tubing in a cooled die to the desired radius. The use of the ice as a filler material provides uniform cross-sectional bends of the tubing and upon removal of the ice provides an uncontaminated interior of the tubing which will enable it to be used in its intended application without encountering residual contaminants in the tubing due to the presence of the filler material.

Recommendations for Accessibility Standards for Children's Environments: Task Five. Technical Report.

ERIC Educational Resources Information Center

North Carolina State Univ., Raleigh. Center for Accessible Housing.

The purpose of this project was to develop and present a set of recommendations for supplements to the existing Uniform Federal Accessibility Standards (UFAS) that would apply to environments used by children with physical disabilities. The work was subdivided into six phases: (1) review of selected codes, standards and guidelines; (2) review of…

17 CFR 269.7 - Form ID, uniform application for access codes to file on EDGAR.

Code of Federal Regulations, 2010 CFR

2010-04-01

... on to the EDGAR system, submit filings, and change its CCC. (d) Password Modification Authorization Code (PMAC)—allows a filer, filing agent or training agent to change its Password. [69 FR 22710, Apr... Sections Affected, which appears in the Finding Aids section of the printed volume and on GPO Access. ...

17 CFR 249.446 - Form ID, uniform application for access codes to file on EDGAR.

Code of Federal Regulations, 2010 CFR

2010-04-01

... log on to the EDGAR system, submit filings, and change its CCC. (d) Password Modification Authorization Code (PMAC)—allows a filer, filing agent or training agent to change its Password. [69 FR 22710... Sections Affected, which appears in the Finding Aids section of the printed volume and on GPO Access. ...

Common Data Models and Efficient Reproducible Workflows for Distributed Ocean Model Skill Assessment

NASA Astrophysics Data System (ADS)

Signell, R. P.; Snowden, D. P.; Howlett, E.; Fernandes, F. A.

2014-12-01

Model skill assessment requires discovery, access, analysis, and visualization of information from both sensors and models, and traditionally has been possible only by a few experts. The US Integrated Ocean Observing System (US-IOOS) consists of 17 Federal Agencies and 11 Regional Associations that produce data from various sensors and numerical models; exactly the information required for model skill assessment. US-IOOS is seeking to develop documented skill assessment workflows that are standardized, efficient, and reproducible so that a much wider community can participate in the use and assessment of model results. Standardization requires common data models for observational and model data. US-IOOS relies on the CF Conventions for observations and structured grid data, and on the UGRID Conventions for unstructured (e.g. triangular) grid data. This allows applications to obtain only the data they require in a uniform and parsimonious way using web services: OPeNDAP for model output and OGC Sensor Observation Service (SOS) for observed data. Reproducibility is enabled with IPython Notebooks shared on GitHub (http://github.com/ioos). These capture the entire skill assessment workflow, including user input, search, access, analysis, and visualization, ensuring that workflows are self-documenting and reproducible by anyone, using free software. Python packages for common data models are Pyugrid and the British Met Office Iris package. Python packages required to run the workflows (pyugrid, pyoos, and the British Met Office Iris package) are also available on GitHub and on Binstar.org so that users can run scenarios using the free Anaconda Python distribution. Hosted services such as Wakari enable anyone to reproduce these workflows for free, without installing any software locally, using just their web browser. We are also experimenting with Wakari Enterprise, which allows multi-user access from a web browser to an IPython Server running where large quantities of model output reside, increasing the efficiency. The open development and distribution of these workflows, and the software on which they depend, is an educational resource for those new to the field and a center of focus where practitioners can contribute new software and ideas.

Efficient Unsteady Flow Visualization with High-Order Access Dependencies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Jiang; Guo, Hanqi; Yuan, Xiaoru

We present a novel high-order access dependencies based model for efficient pathline computation in unsteady flow visualization. By taking longer access sequences into account to model more sophisticated data access patterns in particle tracing, our method greatly improves the accuracy and reliability in data access prediction. In our work, high-order access dependencies are calculated by tracing uniformly-seeded pathlines in both forward and backward directions in a preprocessing stage. The effectiveness of our proposed approach is demonstrated through a parallel particle tracing framework with high-order data prefetching. Results show that our method achieves higher data locality and hence improves the efficiencymore » of pathline computation.« less

NCBI2RDF: enabling full RDF-based access to NCBI databases.

PubMed

Anguita, Alberto; García-Remesal, Miguel; de la Iglesia, Diana; Maojo, Victor

2013-01-01

RDF has become the standard technology for enabling interoperability among heterogeneous biomedical databases. The NCBI provides access to a large set of life sciences databases through a common interface called Entrez. However, the latter does not provide RDF-based access to such databases, and, therefore, they cannot be integrated with other RDF-compliant databases and accessed via SPARQL query interfaces. This paper presents the NCBI2RDF system, aimed at providing RDF-based access to the complete NCBI data repository. This API creates a virtual endpoint for servicing SPARQL queries over different NCBI repositories and presenting to users the query results in SPARQL results format, thus enabling this data to be integrated and/or stored with other RDF-compliant repositories. SPARQL queries are dynamically resolved, decomposed, and forwarded to the NCBI-provided E-utilities programmatic interface to access the NCBI data. Furthermore, we show how our approach increases the expressiveness of the native NCBI querying system, allowing several databases to be accessed simultaneously. This feature significantly boosts productivity when working with complex queries and saves time and effort to biomedical researchers. Our approach has been validated with a large number of SPARQL queries, thus proving its reliability and enhanced capabilities in biomedical environments.

Application of Raman spectroscopy for on-line monitoring of low dose blend uniformity.

PubMed

Hausman, Debra S; Cambron, R Thomas; Sakr, Adel

2005-07-14

On-line Raman spectroscopy was used to evaluate the effect of blending time on low dose, 1%, blend uniformity of azimilide dihydrochloride. An 8 qt blender was used for the experiments and instrumented with a Raman probe through the I-bar port. The blender was slowed to 6.75 rpm to better illustrate the blending process (normal speed is 25 rpm). Uniformity was reached after 20 min of blending at 6.75 rpm (135 revolutions or 5.4 min at 25 rpm). On-line Raman analysis of blend uniformity provided more benefits than traditional thief sampling and off-line analysis. On-line Raman spectroscopy enabled generating data rich blend profiles, due to the ability to collect a large number of samples during the blending process (sampling every 20s). In addition, the Raman blend profile was rapidly generated, compared to the lengthy time to complete a blend profile with thief sampling and off-line analysis. The on-line Raman blend uniformity results were also significantly correlated (p-value < 0.05) to the HPLC uniformity results of thief samples.

DESM: portal for microbial knowledge exploration systems.

PubMed

Salhi, Adil; Essack, Magbubah; Radovanovic, Aleksandar; Marchand, Benoit; Bougouffa, Salim; Antunes, Andre; Simoes, Marta Filipa; Lafi, Feras F; Motwalli, Olaa A; Bokhari, Ameerah; Malas, Tariq; Amoudi, Soha Al; Othum, Ghofran; Allam, Intikhab; Mineta, Katsuhiko; Gao, Xin; Hoehndorf, Robert; C Archer, John A; Gojobori, Takashi; Bajic, Vladimir B

2016-01-04

Microorganisms produce an enormous variety of chemical compounds. It is of general interest for microbiology and biotechnology researchers to have means to explore information about molecular and genetic basis of functioning of different microorganisms and their ability for bioproduction. To enable such exploration, we compiled 45 topic-specific knowledgebases (KBs) accessible through DESM portal (www.cbrc.kaust.edu.sa/desm). The KBs contain information derived through text-mining of PubMed information and complemented by information data-mined from various other resources (e.g. ChEBI, Entrez Gene, GO, KOBAS, KEGG, UniPathways, BioGrid). All PubMed records were indexed using 4,538,278 concepts from 29 dictionaries, with 1 638 986 records utilized in KBs. Concepts used are normalized whenever possible. Most of the KBs focus on a particular type of microbial activity, such as production of biocatalysts or nutraceuticals. Others are focused on specific categories of microorganisms, e.g. streptomyces or cyanobacteria. KBs are all structured in a uniform manner and have a standardized user interface. Information exploration is enabled through various searches. Users can explore statistically most significant concepts or pairs of concepts, generate hypotheses, create interactive networks of associated concepts and export results. We believe DESM will be a useful complement to the existing resources to benefit microbiology and biotechnology research. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

Optimizing the NASA Technical Report Server

NASA Technical Reports Server (NTRS)

Nelson, Michael L.; Maa, Ming-Hokng

1996-01-01

The NASA Technical Report Server (NTRS), a World Wide Web report distribution NASA technical publications service, is modified for performance enhancement, greater protocol support, and human interface optimization. Results include: Parallel database queries, significantly decreasing user access times by an average factor of 2.3; access from clients behind firewalls and/ or proxies which truncate excessively long Uniform Resource Locators (URLs); access to non-Wide Area Information Server (WAIS) databases and compatibility with the 239-50.3 protocol; and a streamlined user interface.

Conformal chemically resistant coatings for microflow devices

DOEpatents

Folta, James A.; Zdeblick, Mark

2003-05-13

A process for coating the inside surfaces of silicon microflow devices, such as electrophoresis microchannels, with a low-stress, conformal (uniform) silicon nitride film which has the ability to uniformly coat deeply-recessed cavities with, for example, aspect ratios of up to 40:1 or higher. The silicon nitride coating allows extended exposure to caustic solutions. The coating enables a microflow device fabricated in silicon to be resistant to all classes of chemicals: acids, bases, and solvents. The process involves low-pressure (vacuum) chemical vapor deposition. The ultra-low-stress silicon nitride deposition process allows 1-2 .mu.m thick films without cracks, and so enables extended chemical protection of a silicon microflow device against caustics for up to 1 year. Tests have demonstrated the resistance of the films to caustic solutions at both ambient and elevated temperatures to 65.degree. C.

Stacked waveguide reactors with gradient embedded scatterers for high-capacity water cleaning

DOE PAGES

Ahsan, Syed Saad; Gumus, Abdurrahman; Erickson, David

2015-11-04

We present a compact water-cleaning reactor with stacked layers of waveguides containing gradient patterns of optical scatterers that enable uniform light distribution and augmented water-cleaning rates. Previous photocatalytic reactors using immersion, external, or distributive lamps suffer from poor light distribution that impedes scalability. Here, we use an external UV-source to direct photons into stacked waveguide reactors where we scatter the photons uniformly over the length of the waveguide to thin films of TiO 2-catalysts. In conclusion, we also show 4.5 times improvement in activity over uniform scatterer designs, demonstrate a degradation of 67% of the organic dye, and characterize themore » degradation rate constant.« less

Stacked waveguide reactors with gradient embedded scatterers for high-capacity water cleaning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ahsan, Syed Saad; Gumus, Abdurrahman; Erickson, David

We present a compact water-cleaning reactor with stacked layers of waveguides containing gradient patterns of optical scatterers that enable uniform light distribution and augmented water-cleaning rates. Previous photocatalytic reactors using immersion, external, or distributive lamps suffer from poor light distribution that impedes scalability. Here, we use an external UV-source to direct photons into stacked waveguide reactors where we scatter the photons uniformly over the length of the waveguide to thin films of TiO 2-catalysts. In conclusion, we also show 4.5 times improvement in activity over uniform scatterer designs, demonstrate a degradation of 67% of the organic dye, and characterize themore » degradation rate constant.« less

Engineered surface scatterers in edge-lit slab waveguides to improve light delivery in algae cultivation.

PubMed

Ahsan, Syed Saad; Pereyra, Brandon; Jung, Erica E; Erickson, David

2014-10-20

Most existing photobioreactors do a poor job of distributing light uniformly due to shading effects. One method by which this could be improved is through the use of internal wave-guiding structures incorporating engineered light scattering schemes. By varying the density of these scatterers, one can control the spatial distribution of light inside the reactor enabling better uniformity of illumination. Here, we compare a number of light scattering schemes and evaluate their ability to enhance biomass accumulation. We demonstrate a design for a gradient distribution of surface scatterers with uniform lateral scattering intensity that is superior for algal biomass accumulation, resulting in a 40% increase in the growth rate.

Avoiding the Peril of Publishing Qualitative Scholarship in Predatory Journals

ERIC Educational Resources Information Center

Beall, Jeffrey

2013-01-01

Scholarly communication is caught between the traditions of the past and the possibilities of the future. Specifically, scholarly open-access publishing is enabling greater access to research but, at the same time, is enabling an abundance of low quality publishers and an apparent increase in author misconduct. In this article I examine six…

Service composition towards increasing end-user accessibility.

PubMed

Kaklanis, Nikolaos; Votis, Konstantinos; Tzovaras, Dimitrios

2015-01-01

This paper presents the Cloud4all Service Synthesizer Tool, a framework that enables efficient orchestration of accessibility services, as well as their combination into complex forms, providing more advanced functionalities towards increasing the accessibility of end-users with various types of functional limitations. The supported services are described formally within an ontology, enabling, thus, semantic service composition. The proposed service composition approach is based on semantic matching between services specifications on the one hand and user needs/preferences and current context of use on the other hand. The use of automatic composition of accessibility services can significantly enhance end-users' accessibility, especially in cases where assistive solutions are not available in their device.

The uniformity study of non-oxide thin film at device level using electron energy loss spectroscopy

NASA Astrophysics Data System (ADS)

Li, Zhi-Peng; Zheng, Yuankai; Li, Shaoping; Wang, Haifeng

2018-05-01

Electron energy loss spectroscopy (EELS) has been widely used as a chemical analysis technique to characterize materials chemical properties, such as element valence states, atoms/ions bonding environment. This study provides a new method to characterize physical properties (i.e., film uniformity, grain orientations) of non-oxide thin films in the magnetic device by using EELS microanalysis on scanning transmission electron microscope. This method is based on analyzing white line ratio of spectra and related extended energy loss fine structures so as to correlate it with thin film uniformity. This new approach can provide an effective and sensitive method to monitor/characterize thin film quality (i.e., uniformity) at atomic level for thin film development, which is especially useful for examining ultra-thin films (i.e., several nanometers) or embedded films in devices for industry applications. More importantly, this technique enables development of quantitative characterization of thin film uniformity and it would be a remarkably useful technique for examining various types of devices for industrial applications.

Point Positioning Service for Natural Hazard Monitoring

NASA Astrophysics Data System (ADS)

Bar-Sever, Y. E.

2014-12-01

In an effort to improve natural hazard monitoring, JPL has invested in updating and enlarging its global real-time GNSS tracking network, and has launched a unique service - real-time precise positioning for natural hazard monitoring, entitled GREAT Alert (GNSS Real-Time Earthquake and Tsunami Alert). GREAT Alert leverages the full technological and operational capability of the JPL's Global Differential GPS System [www.gdgps.net] to offer owners of real-time dual-frequency GNSS receivers: Sub-5 cm (3D RMS) real-time, absolute positioning in ITRF08, regardless of location Under 5 seconds turnaround time Full covariance information Estimates of ancillary parameters (such as troposphere) optionally provided This service enables GNSS networks operators to instantly have access to the most accurate and reliable real-time positioning solutions for their sites, and also to the hundreds of participating sites globally, assuring inter-consistency and uniformity across all solutions. Local authorities with limited technical and financial resources can now access to the best technology, and share environmental data to the benefit of the entire pacific region. We will describe the specialized precise point positioning techniques employed by the GREAT Alert service optimized for natural hazard monitoring, and in particular Earthquake monitoring. We address three fundamental aspects of these applications: 1) small and infrequent motion, 2) the availability of data at a central location, and 3) the need for refined solutions at several time scales

Uniform rotating field network structure to efficiently package a magnetic bubble domain memory

NASA Technical Reports Server (NTRS)

Murray, Glen W. (Inventor); Chen, Thomas T. (Inventor); Wolfshagen, Ronald G. (Inventor); Ypma, John E. (Inventor)

1978-01-01

A unique and compact open coil rotating magnetic field network structure to efficiently package an array of bubble domain devices is disclosed. The field network has a configuration which effectively enables selected bubble domain devices from the array to be driven in a vertical magnetic field and in an independent and uniform horizontal rotating magnetic field. The field network is suitably adapted to minimize undesirable inductance effects, improve capabilities of heat dissipation, and facilitate repair or replacement of a bubble device.

Process For Patterning Dispenser-Cathode Surfaces

NASA Technical Reports Server (NTRS)

Garner, Charles E.; Deininger, William D.

1989-01-01

Several microfabrication techniques combined into process cutting slots 100 micrometer long and 1 to 5 micrometer wide into tungsten dispenser cathodes for traveling-wave tubes. Patterned photoresist serves as mask for etching underlying aluminum. Chemically-assisted ion-beam etching with chlorine removes exposed parts of aluminum layer. Etching with fluorine or chlorine trifluoride removes tungsten not masked by aluminum layer. Slots enable more-uniform low-work function coating dispensed to electron-emitting surface. Emission of electrons therefore becomes more uniform over cathode surface.

CILogon: An Integrated Identity and Access Management Platform for Science

NASA Astrophysics Data System (ADS)

Basney, J.

2016-12-01

When scientists work together, they use web sites and other software to share their ideas and data. To ensure the integrity of their work, these systems require the scientists to log in and verify that they are part of the team working on a particular science problem. Too often, the identity and access verification process is a stumbling block for the scientists. Scientific research projects are forced to invest time and effort into developing and supporting Identity and Access Management (IAM) services, distracting them from the core goals of their research collaboration. CILogon provides an IAM platform that enables scientists to work together to meet their IAM needs more effectively so they can allocate more time and effort to their core mission of scientific research. The CILogon platform enables federated identity management and collaborative organization management. Federated identity management enables researchers to use their home organization identities to access cyberinfrastructure, rather than requiring yet another username and password to log on. Collaborative organization management enables research projects to define user groups for authorization to collaboration platforms (e.g., wikis, mailing lists, and domain applications). CILogon's IAM platform serves the unique needs of research collaborations, namely the need to dynamically form collaboration groups across organizations and countries, sharing access to data, instruments, compute clusters, and other resources to enable scientific discovery. CILogon provides a software-as-a-service platform to ease integration with cyberinfrastructure, while making all software components publicly available under open source licenses to enable re-use. Figure 1 illustrates the components and interfaces of this platform. CILogon has been operational since 2010 and has been used by over 7,000 researchers from more than 170 identity providers to access cyberinfrastructure including Globus, LIGO, Open Science Grid, SeedMe, and XSEDE. The "CILogon 2.0" platform, launched in 2016, adds support for virtual organization (VO) membership management, identity linking, international collaborations, and standard integration protocols, through integration with the Internet2 COmanage collaboration software.

Are pediatric Open Access journals promoting good publication practice? An analysis of author instructions.

PubMed

Meerpohl, Joerg J; Wolff, Robert F; Antes, Gerd; von Elm, Erik

2011-04-09

Several studies analyzed whether conventional journals in general medicine or specialties such as pediatrics endorse recommendations aiming to improve publication practice. Despite evidence showing benefits of these recommendations, the proportion of endorsing journals has been moderate to low and varied considerably for different recommendations. About half of pediatric journals indexed in the Journal Citation Report referred to the Uniform Requirements for Manuscripts of the International Committee of Medical Journal Editors (ICMJE) but only about a quarter recommended registration of trials. We aimed to investigate to what extent pediatric open-access (OA) journals endorse these recommendations. We hypothesized that a high proportion of these journals have adopted recommendations on good publication practice since OA electronic publishing has been associated with a number of editorial innovations aiming at improved access and transparency. We identified 41 journals publishing original research in the subject category "Health Sciences, Medicine (General), Pediatrics" of the Directory of Open Access Journals http://www.doaj.org. From the journals' online author instructions we extracted information regarding endorsement of four domains of editorial policy: the Uniform Requirements for Manuscripts, trial registration, disclosure of conflicts of interest and five major reporting guidelines such as the CONSORT (Consolidated Standards of Reporting Trials) statement. Two investigators collected data independently. The Uniform Requirements were mentioned by 27 (66%) pediatric OA journals. Thirteen (32%) required or recommended trial registration prior to publication of a trial report. Conflict of interest policies were stated by 25 journals (61%). Advice about reporting guidelines was less frequent: CONSORT was referred to by 12 journals (29%) followed by other reporting guidelines (MOOSE, PRISMA or STARD) (8 journals, 20%) and STROBE (3 journals, 7%). The EQUATOR network, a platform of several guideline initiatives, was acknowledged by 4 journals (10%). Journals published by OA publishing houses gave more guidance than journals published by professional societies or other publishers. Pediatric OA journals mentioned certain recommendations such as the Uniform Requirements or trial registration more frequently than conventional journals; however, endorsement is still only moderate. Further research should confirm these exploratory findings in other medical fields and should clarify what the motivations and barriers are in implementing such policies.

Are pediatric Open Access journals promoting good publication practice? An analysis of author instructions

PubMed Central

2011-01-01

Background Several studies analyzed whether conventional journals in general medicine or specialties such as pediatrics endorse recommendations aiming to improve publication practice. Despite evidence showing benefits of these recommendations, the proportion of endorsing journals has been moderate to low and varied considerably for different recommendations. About half of pediatric journals indexed in the Journal Citation Report referred to the Uniform Requirements for Manuscripts of the International Committee of Medical Journal Editors (ICMJE) but only about a quarter recommended registration of trials. We aimed to investigate to what extent pediatric open-access (OA) journals endorse these recommendations. We hypothesized that a high proportion of these journals have adopted recommendations on good publication practice since OA electronic publishing has been associated with a number of editorial innovations aiming at improved access and transparency. Methods We identified 41 journals publishing original research in the subject category "Health Sciences, Medicine (General), Pediatrics" of the Directory of Open Access Journals http://www.doaj.org. From the journals' online author instructions we extracted information regarding endorsement of four domains of editorial policy: the Uniform Requirements for Manuscripts, trial registration, disclosure of conflicts of interest and five major reporting guidelines such as the CONSORT (Consolidated Standards of Reporting Trials) statement. Two investigators collected data independently. Results The Uniform Requirements were mentioned by 27 (66%) pediatric OA journals. Thirteen (32%) required or recommended trial registration prior to publication of a trial report. Conflict of interest policies were stated by 25 journals (61%). Advice about reporting guidelines was less frequent: CONSORT was referred to by 12 journals (29%) followed by other reporting guidelines (MOOSE, PRISMA or STARD) (8 journals, 20%) and STROBE (3 journals, 7%). The EQUATOR network, a platform of several guideline initiatives, was acknowledged by 4 journals (10%). Journals published by OA publishing houses gave more guidance than journals published by professional societies or other publishers. Conclusions Pediatric OA journals mentioned certain recommendations such as the Uniform Requirements or trial registration more frequently than conventional journals; however, endorsement is still only moderate. Further research should confirm these exploratory findings in other medical fields and should clarify what the motivations and barriers are in implementing such policies. PMID:21477335

An investigation into the effects of excipient particle size, blending techniques and processing parameters on the homogeneity and content uniformity of a blend containing low-dose model drug

PubMed Central

Alyami, Hamad; Dahmash, Eman; Bowen, James

2017-01-01

Powder blend homogeneity is a critical attribute in formulation development of low dose and potent active pharmaceutical ingredients (API) yet a complex process with multiple contributing factors. Excipient characteristics play key role in efficient blending process and final product quality. In this work the effect of excipient type and properties, blending technique and processing time on content uniformity was investigated. Powder characteristics for three commonly used excipients (starch, pregelatinised starch and microcrystalline cellulose) were initially explored using laser diffraction particle size analyser, angle of repose for flowability, followed by thorough evaluations of surface topography employing scanning electron microscopy and interferometry. Blend homogeneity was evaluated based on content uniformity analysis of the model API, ergocalciferol, using a validated analytical technique. Flowability of powders were directly related to particle size and shape, while surface topography results revealed the relationship between surface roughness and ability of excipient with high surface roughness to lodge fine API particles within surface groves resulting in superior uniformity of content. Of the two blending techniques, geometric blending confirmed the ability to produce homogeneous blends at low dilution when processed for longer durations, whereas manual ordered blending failed to achieve compendial requirement for content uniformity despite mixing for 32 minutes. Employing the novel dry powder hybrid mixer device, developed at Aston University laboratory, results revealed the superiority of the device and enabled the production of homogenous blend irrespective of excipient type and particle size. Lower dilutions of the API (1% and 0.5% w/w) were examined using non-sieved excipients and the dry powder hybrid mixing device enabled the development of successful blends within compendial requirements and low relative standard deviation. PMID:28609454

An investigation into the effects of excipient particle size, blending techniques and processing parameters on the homogeneity and content uniformity of a blend containing low-dose model drug.

PubMed

Alyami, Hamad; Dahmash, Eman; Bowen, James; Mohammed, Afzal R

2017-01-01

Powder blend homogeneity is a critical attribute in formulation development of low dose and potent active pharmaceutical ingredients (API) yet a complex process with multiple contributing factors. Excipient characteristics play key role in efficient blending process and final product quality. In this work the effect of excipient type and properties, blending technique and processing time on content uniformity was investigated. Powder characteristics for three commonly used excipients (starch, pregelatinised starch and microcrystalline cellulose) were initially explored using laser diffraction particle size analyser, angle of repose for flowability, followed by thorough evaluations of surface topography employing scanning electron microscopy and interferometry. Blend homogeneity was evaluated based on content uniformity analysis of the model API, ergocalciferol, using a validated analytical technique. Flowability of powders were directly related to particle size and shape, while surface topography results revealed the relationship between surface roughness and ability of excipient with high surface roughness to lodge fine API particles within surface groves resulting in superior uniformity of content. Of the two blending techniques, geometric blending confirmed the ability to produce homogeneous blends at low dilution when processed for longer durations, whereas manual ordered blending failed to achieve compendial requirement for content uniformity despite mixing for 32 minutes. Employing the novel dry powder hybrid mixer device, developed at Aston University laboratory, results revealed the superiority of the device and enabled the production of homogenous blend irrespective of excipient type and particle size. Lower dilutions of the API (1% and 0.5% w/w) were examined using non-sieved excipients and the dry powder hybrid mixing device enabled the development of successful blends within compendial requirements and low relative standard deviation.

Disappearing Act: Persistence and Attrition of Uniform Resource Locators (URLs) in an Open Access Medical Journal

ERIC Educational Resources Information Center

Nagaraja, Aragudige; Joseph, Shine A.; Polen, Hyla H.; Clauson, Kevin A.

2011-01-01

Purpose: The aim of this paper is to assess and catalogue the magnitude of URL attrition in a high-impact, open access (OA) general medical journal. Design/methodology/approach: All "Public Library of Science Medicine (PLoS Medicine)" articles for 2005-2007 were evaluated and the following items were assessed: number of entries per issue; type of…

Standards-based publication and sharing of time series information in the DRIHM project: a EU-US collaboration

NASA Astrophysics Data System (ADS)

Hooper, Richard; Zaslavsky, Ilya; Parodi, Antonio; Gochis, David; Jha, Shantenu; Whitenack, Thomas; Valentine, David; Caumont, Olivier; Dekic, Ljiljana; Ivkovic, Marija; Molini, Luca; Bedrina, Tatiana; Gijsbers, Peter J. A.; de Rooij, Erik; Rebora, Nicola

2013-04-01

To enable a plug-and-play infrastructure, the European DRIHM (Distributed Research Infrastructure for Hydro-Meteorology) project aims to develop a comprehensive data publication and sharing system presenting uniform standards-based data discovery and access interfaces for hydrometeorological data collected by DRIHM partners in several European countries. This is a challenging task due to heterogeneity in types of data being collected and organized for modeling, and different semantic and structural conventions adopted by different data publishers. To meet this goal, the DRIHM project, and its DRIHM2US extension, collaborates with the recently funded US SCIHM (Standards-based Cyberinfrastructure for HydroMeteorology) project to develop a data sharing infrastructure for time series information. We report initial results of the application of the data integrating technologies developed by the NSF-funded CUAHSI HIS (Consortium of Universities for the Advancement of Hydrologic Data, Inc., Hydrologic Information System) project, to information collected within DRIHM. The CUAHSI HIS system has been widely used in the US; it provides access to about a hundred water data collections that can be queried via uniform web services. The DRIHM partners initially implementing the system, include the CIMA Research Foundation (Italy), the French National Center for Scientific Research (CNRS), and the Republic Hydrometeorological Service of Serbia. The collected time series information was ingested into CUAHSI Observations Data Model databases, and water data services were created for each of the partners. At the time of writing, the water data services include SOAP and REST endpoints that provide access to the time series in WaterML 1 and WaterML 2.0 formats. The former encoding, developed by CUAHSI HIS, has been adopted by a number of federal agencies and research groups in the US, while the latter, created by an international group of experts under the aegis of the Hydrology Domain Working Group of the Open Geospatial Consortium and the World Meteorological Organization, has been recently adopted as an international standard for exchanging hydrologic data. The services are registered at the central catalog, which supports discovery of time series based on their spatio-temporal characteristics and on variable semantics. The semantics of the measurements is aligned , in the process of publication and service registration, with a set of centrally managed controlled vocabularies and a parameter vocabulary. Data from multiple collections can be discovered, accessed, visualized and analyzed using CUAHSI HydroDesktop software, or other clients that support water data service interfaces. While HydroDesktop relies on WaterML 1 format, the Delft FEWS system, maintained by a DRIHM partner Deltares, is already capable of ingesting WaterML 2.0 services, which enables interfacing WaterML 2.0-formatted streams with forecast models. Development of a consistent data sharing system is one of the first steps in realizing DRIHM objectives. Next steps include further integration of water data services with simulation models, WRF and WRF-Hydro in particular, and integrating point time series with gridded information to be used as model input. We discuss these additional steps and associated challenges, and demonstrate the complementarity and benefits of US-EU collaboration in the development of global standards-based infrastructure for hydrometeorological data.

CHRR: coordinate hit-and-run with rounding for uniform sampling of constraint-based models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haraldsdóttir, Hulda S.; Cousins, Ben; Thiele, Ines

In constraint-based metabolic modelling, physical and biochemical constraints define a polyhedral convex set of feasible flux vectors. Uniform sampling of this set provides an unbiased characterization of the metabolic capabilities of a biochemical network. However, reliable uniform sampling of genome-scale biochemical networks is challenging due to their high dimensionality and inherent anisotropy. Here, we present an implementation of a new sampling algorithm, coordinate hit-and-run with rounding (CHRR). This algorithm is based on the provably efficient hit-and-run random walk and crucially uses a preprocessing step to round the anisotropic flux set. CHRR provably converges to a uniform stationary sampling distribution. Wemore » apply it to metabolic networks of increasing dimensionality. We show that it converges several times faster than a popular artificial centering hit-and-run algorithm, enabling reliable and tractable sampling of genome-scale biochemical networks.« less

CHRR: coordinate hit-and-run with rounding for uniform sampling of constraint-based models

DOE PAGES

Haraldsdóttir, Hulda S.; Cousins, Ben; Thiele, Ines; ...

2017-01-31

In constraint-based metabolic modelling, physical and biochemical constraints define a polyhedral convex set of feasible flux vectors. Uniform sampling of this set provides an unbiased characterization of the metabolic capabilities of a biochemical network. However, reliable uniform sampling of genome-scale biochemical networks is challenging due to their high dimensionality and inherent anisotropy. Here, we present an implementation of a new sampling algorithm, coordinate hit-and-run with rounding (CHRR). This algorithm is based on the provably efficient hit-and-run random walk and crucially uses a preprocessing step to round the anisotropic flux set. CHRR provably converges to a uniform stationary sampling distribution. Wemore » apply it to metabolic networks of increasing dimensionality. We show that it converges several times faster than a popular artificial centering hit-and-run algorithm, enabling reliable and tractable sampling of genome-scale biochemical networks.« less

Accessible triple-phase boundary length: A performance metric to account for transport pathways in heterogeneous electrochemical materials

NASA Astrophysics Data System (ADS)

Nakajo, A.; Cocco, A. P.; DeGostin, M. B.; Peracchio, A. A.; Cassenti, B. N.; Cantoni, M.; Van herle, J.; Chiu, W. K. S.

2016-09-01

The performance of materials for electrochemical energy conversion and storage depends upon the number of electrocatalytic sites available for reaction and their accessibility by the transport of reactants and products. For solid oxide fuel/electrolysis cell materials, standard 3-D measurements such as connected triple-phase boundary (TPB) length and effective transport properties partially inform on how local geometry and network topology causes variability in TPB accessibility. A new measurement, the accessible TPB, is proposed to quantify these effects in detail and characterize material performance. The approach probes the reticulated pathways to each TPB using an analytical electrochemical fin model applied to a 3-D discrete representation of the heterogeneous structure provided by skeleton-based partitioning. The method is tested on artificial and real structures imaged by 3-D x-ray and electron microscopy. The accessible TPB is not uniform and the pattern varies depending upon the structure. Connected TPBs can be even passivated. The sensitivity to manipulations of the local 3-D geometry and topology that standard measurements cannot capture is demonstrated. The clear presence of preferential pathways showcases a non-uniform utilization of the 3-D structure that potentially affects the performance and the resilience to alterations due to degradation phenomena. The concepts presented also apply to electrochemical energy storage and conversion devices such as other types of fuel cells, electrolyzers, batteries and capacitors.

NCBI2RDF: Enabling Full RDF-Based Access to NCBI Databases

PubMed Central

Anguita, Alberto; García-Remesal, Miguel; de la Iglesia, Diana; Maojo, Victor

2013-01-01

RDF has become the standard technology for enabling interoperability among heterogeneous biomedical databases. The NCBI provides access to a large set of life sciences databases through a common interface called Entrez. However, the latter does not provide RDF-based access to such databases, and, therefore, they cannot be integrated with other RDF-compliant databases and accessed via SPARQL query interfaces. This paper presents the NCBI2RDF system, aimed at providing RDF-based access to the complete NCBI data repository. This API creates a virtual endpoint for servicing SPARQL queries over different NCBI repositories and presenting to users the query results in SPARQL results format, thus enabling this data to be integrated and/or stored with other RDF-compliant repositories. SPARQL queries are dynamically resolved, decomposed, and forwarded to the NCBI-provided E-utilities programmatic interface to access the NCBI data. Furthermore, we show how our approach increases the expressiveness of the native NCBI querying system, allowing several databases to be accessed simultaneously. This feature significantly boosts productivity when working with complex queries and saves time and effort to biomedical researchers. Our approach has been validated with a large number of SPARQL queries, thus proving its reliability and enhanced capabilities in biomedical environments. PMID:23984425

Enabling access to new WHO essential medicines: the case for nicotine replacement therapies

PubMed Central

2010-01-01

Nicotine replacement therapies (NRT) are powerful tools for the successful treatment of nicotine addiction and tobacco use. The medicines are clinically effective, supported by the Framework Convention on Tobacco Control, and are now World Health Organization-approved essential medicines. Enabling global access to NRT remains a challenge given ongoing confusion and misperceptions about their efficacy, cost-effectiveness, and availability with respect to other tobacco control and public health opportunities. In this commentary, we review existing evidence and guidelines to make the case for global access to NRT highlighting the smoker's right to access treatment to sensibly address nicotine addiction. PMID:21092092

Achieving human and machine accessibility of cited data in scholarly publications

PubMed Central

Starr, Joan; Castro, Eleni; Crosas, Mercè; Dumontier, Michel; Downs, Robert R.; Duerr, Ruth; Haak, Laurel L.; Haendel, Melissa; Herman, Ivan; Hodson, Simon; Hourclé, Joe; Kratz, John Ernest; Lin, Jennifer; Nielsen, Lars Holm; Nurnberger, Amy; Proell, Stefan; Rauber, Andreas; Sacchi, Simone; Smith, Arthur; Taylor, Mike; Clark, Tim

2015-01-01

Reproducibility and reusability of research results is an important concern in scientific communication and science policy. A foundational element of reproducibility and reusability is the open and persistently available presentation of research data. However, many common approaches for primary data publication in use today do not achieve sufficient long-term robustness, openness, accessibility or uniformity. Nor do they permit comprehensive exploitation by modern Web technologies. This has led to several authoritative studies recommending uniform direct citation of data archived in persistent repositories. Data are to be considered as first-class scholarly objects, and treated similarly in many ways to cited and archived scientific and scholarly literature. Here we briefly review the most current and widely agreed set of principle-based recommendations for scholarly data citation, the Joint Declaration of Data Citation Principles (JDDCP). We then present a framework for operationalizing the JDDCP; and a set of initial recommendations on identifier schemes, identifier resolution behavior, required metadata elements, and best practices for realizing programmatic machine actionability of cited data. The main target audience for the common implementation guidelines in this article consists of publishers, scholarly organizations, and persistent data repositories, including technical staff members in these organizations. But ordinary researchers can also benefit from these recommendations. The guidance provided here is intended to help achieve widespread, uniform human and machine accessibility of deposited data, in support of significantly improved verification, validation, reproducibility and re-use of scholarly/scientific data. PMID:26167542

Achieving human and machine accessibility of cited data in scholarly publications.

PubMed

Starr, Joan; Castro, Eleni; Crosas, Mercè; Dumontier, Michel; Downs, Robert R; Duerr, Ruth; Haak, Laurel L; Haendel, Melissa; Herman, Ivan; Hodson, Simon; Hourclé, Joe; Kratz, John Ernest; Lin, Jennifer; Nielsen, Lars Holm; Nurnberger, Amy; Proell, Stefan; Rauber, Andreas; Sacchi, Simone; Smith, Arthur; Taylor, Mike; Clark, Tim

Reproducibility and reusability of research results is an important concern in scientific communication and science policy. A foundational element of reproducibility and reusability is the open and persistently available presentation of research data. However, many common approaches for primary data publication in use today do not achieve sufficient long-term robustness, openness, accessibility or uniformity. Nor do they permit comprehensive exploitation by modern Web technologies. This has led to several authoritative studies recommending uniform direct citation of data archived in persistent repositories. Data are to be considered as first-class scholarly objects, and treated similarly in many ways to cited and archived scientific and scholarly literature. Here we briefly review the most current and widely agreed set of principle-based recommendations for scholarly data citation, the Joint Declaration of Data Citation Principles (JDDCP). We then present a framework for operationalizing the JDDCP; and a set of initial recommendations on identifier schemes, identifier resolution behavior, required metadata elements, and best practices for realizing programmatic machine actionability of cited data. The main target audience for the common implementation guidelines in this article consists of publishers, scholarly organizations, and persistent data repositories, including technical staff members in these organizations. But ordinary researchers can also benefit from these recommendations. The guidance provided here is intended to help achieve widespread, uniform human and machine accessibility of deposited data, in support of significantly improved verification, validation, reproducibility and re-use of scholarly/scientific data.

Enabling High Performance Instruments for Astronomy and Space Exploration and ALD

NASA Technical Reports Server (NTRS)

Greer, Frank; Lee, M. C.; Hoenk, M. E.; Jones, T. J.; Jacquot, B. C.; Dickie, M.; Monacos, S.; Nikzad, S.; Day, P.; Leduc, R.;

Enabling Scientists: Serving Sci-Tech Library Users with Disabilities.

ERIC Educational Resources Information Center

Coonin, Bryna

2001-01-01

Discusses how librarians in scientific and technical libraries can contribute to an accessible electronic library environment for users with disabilities to ensure independent access to information. Topics include relevant assistive technologies; creating accessible Web pages; monitoring accessibility of electronic databases; preparing accessible…

Constructing Uniform Resource Locators (URLs) for Searching the Marine Realms Information Bank

USGS Publications Warehouse

Linck, Guthrie A.; Allwardt, Alan O.; Lightsom, Frances L.

2009-01-01

The Marine Realms Information Bank (MRIB) is a digital library that provides access to free online scientific information about the oceans and coastal regions. To search its collection, MRIB uses a Common Gateway Interface (CGI) program, which allows automated search requests using Uniform Resource Locators (URLs). This document provides an overview of how to construct URLs to execute MRIB queries. The parameters listed allow detailed control of which records are retrieved, how they are returned, and how their display is formatted.

The Moon Mineralogy (M3) Imaging Spectrometer: Early Assessment of the Spectral, Radiometric, Spatial and Uniformity Properties

NASA Technical Reports Server (NTRS)

Green, Robert O.; Pieters, C. M.; Boardman, J.; Barr, D.; Bruce, C.; Bousman, J.; Chatterjee, A.; Eastwood, M.; Essandoh, V.; Geier, S.;

Nonimaging polygonal mirrors achieving uniform irradiance distributions on concentrating photovoltaic cells.

PubMed

Schmitz, Max; Dähler, Fabian; Elvinger, François; Pedretti, Andrea; Steinfeld, Aldo

2017-04-10

We introduce a design methodology for nonimaging, single-reflection mirrors with polygonal inlet apertures that generate a uniform irradiance distribution on a polygonal outlet aperture, enabling a multitude of applications within the domain of concentrated photovoltaics. Notably, we present single-mirror concentrators of square and hexagonal perimeter that achieve very high irradiance uniformity on a square receiver at concentrations ranging from 100 to 1000 suns. These optical designs can be assembled in compound concentrators with maximized active area fraction by leveraging tessellation. More advanced multi-mirror concentrators, where each mirror individually illuminates the whole area of the receiver, allow for improved performance while permitting greater flexibility for the concentrator shape and robustness against partial shading of the inlet aperture.

Quantified Trust Levels for Authentication

NASA Astrophysics Data System (ADS)

Thomas, Ivonne; Menzel, Michael; Meinel, Christoph

Service-oriented Architectures (SOAs) facilitate applications to integrate seamlessly services from collaborating business partners regardless of organizational borders. In order to secure access to these services, mechanisms for authentication and authorisation must be deployed that control the access based on identity-related information. To enable a business partners’ users to access the provided services, an identity federation is often established that enables the brokering of identity information across organisational borders. The establishment of such a federation requires complex agreements and contracts that define common policies, obligations and procedures. Generally, this includes obligations on the authentication process as well.

H2O absorption tomography in a diesel aftertreatment system using a polymer film for optical access

NASA Astrophysics Data System (ADS)

Wang, Ze; Sanders, Scott T.; Backhaus, Jacob A.; Munnannur, Achuth; Schmidt, Niklas M.

2017-12-01

Film-optical-access H2O absorption tomography is, for the first time, applied to a practical diesel aftertreatment system. A single rotation stage and a single translation stage are used to move a single laser beam to obtain each of the 3480 line-of-sight measurements used in the tomographic reconstruction. It takes 1 h to acquire one image in a 60-view-angle measurement. H2O images are acquired in a 292.4-mm-diameter selective catalytic reduction (SCR) can with a 5-mm spatial resolution at temperatures in the 158-185 °C range. When no liquid H2O is injected into the gas, the L1 norm-based uniformity index is 0.994, and the average mole fraction error is - 6% based on a separate FTIR measurement. When liquid water is injected through the reductant dosing system designed to inject diesel exhaust fluid, nonuniformity is observed, as evidenced by measured uniformity indices for H2O in the 0.977-0.986 range. A mixing plate installed into the system is able to improve the uniformity of the H2O mole fraction.

CUAHSI Hydrologic Information Systems

NASA Astrophysics Data System (ADS)

Maidment, D.; Zaslavsky, I.; Tarboton, D.; Piasecki, M.; Goodall, J.

2006-12-01

The Consortium of Universities for the Advancement of Hydrologic Science, Inc (CUAHSI) has a Hydrologic Information System (HIS) project, which is supported by NSF to develop infrastructure and services to support the advance of hydrologic science in the United States. This paper provides an overview of the HIS project. A set of web services called WaterOneFlow is being developed to provide better access to water observations data (point measurements of streamflow, water quality, climate and groundwater levels) from government agencies and individual investigator projects. Successful partnerships have been created with the USGS National Water Information System, EPA Storet and the NCDC Climate Data Online. Observations catalogs have been created for stations in the measurement networks of each of these data systems so that they can be queried in a uniform manner through CUAHSI HIS, and data delivered from them directly to the user via web services. A CUAHSI Observations Data Model has been designed for storing individual investigator data and an equivalent set of web services created for that so that individual investigators can publish their data onto the internet in the same format CUAHSI is providing for the federal agency data. These data will be accessed through HIS Servers hosted at the national level by CUAHSI and also by research centers and academic departments for regional application of HIS. An individual user application called HIS Analyst will enable individual hydrologic scientists to access the information from the network of HIS Servers. The present focus is on water observations data but later development of this system will include weather and climate grid information, GIS data, remote sensing data and linkages between data and hydrologic simulation models.

Spatial Access to Faith-based Diabetes Intervention for Guyanese Adults in Schenectady, New York.

PubMed

Hosler, Akiko S; Michaels, Isaac H

2014-07-01

The purpose of this study is to examine whether travel distance would pose a barrier to participation in proposed diabetes intervention programs for Guyanese immigrants at faith-based organizations (FBOs). This study also suggests the most collectively accessible set of FBOs that could serve as intervention sites. Data were extracted from a cross-sectional health interview survey conducted in Schenectady, New York, in 2011. The shortest driving distances from homes to FBOs and to the city's only diabetes education center (DEC) were analyzed among Guyanese and non-Guyanese adults with diabetes and prediabetes (n = 238), using spatial algorithms and Geographic Information System resources. The Guyanese were more likely to belong to a FBO than the non-Guyanese (77.8% vs 61.2%). The mean driving distance to FBO was 1.19 miles (95% CI, 0.98-1.39) for the Guyanese, which was significantly shorter than that for the non-Guyanese (2.87 miles, 95% CI, 1.93-3.82). The Guyanese had uniformly shorter mean and median driving distances in all sociodemographic and health status subcategories as well. Moreover, a higher percentage of the Guyanese lived closer to FBO than to DEC compared to non-Guyanese (52.2% vs 34.7%). It was found that having diabetes intervention at the 4 most popular FBOs (2 Hindu temples and 2 Christian churches) and DEC would provide the most collectively accessible arrangement for the Guyanese. The results suggest that the short driving distance to FBO is a likely enabler that can encourage regular utilization of the faith-based intervention for the Guyanese. © 2014 The Author(s).

What does cooking mean to you?: Perceptions of cooking and factors related to cooking behavior.

PubMed

Wolfson, Julia A; Bleich, Sara N; Smith, Katherine Clegg; Frattaroli, Shannon

2016-02-01

Despite the importance of cooking in American life and evidence suggesting that meals cooked at home are healthier, little is known about perceptions of what it means to cook in the United States. The objective of this study was to describe perceptions of cooking and factors important to how cooking is perceived and practiced among American adults. Seven focus groups (N = 53; 39 female; 35 Black, 16 White, 2 Asian) were conducted from November 2014 to January 2015 in Baltimore City, Maryland. Participants were recruited from two neighborhoods; one with higher median income and access to healthy food and the other with lower income and low access to healthy food. Focus groups were audio recorded, transcribed verbatim and analyzed using a grounded theory approach. Participants' perceptions of cooking varied considerably, regardless of neighborhood income or food access, and spanned a continuum from all scratch cooking to anything made at home. Perceptions of cooking incorporated considerations of whether or how food was heated and the degree of time, effort and love involved if convenience foods were used. Key barriers to cooking included affordability, lack of time, and lack of enjoyment. Key facilitators of frequent cooking included extensive organization and time management to enable participants to incorporate cooking into their daily lives. Cooking is a complex concept and not uniformly understood. Efforts to encourage healthy cooking at home should consider the broad spectrum of activities Americans recognize as cooking as well as the barriers and facilitators to preparing food at home. Public health messages to encourage more frequent cooking should account for the heterogeneity in perspectives about cooking. More research should explore differences in perceptions about cooking in other diverse populations. Copyright © 2015 Elsevier Ltd. All rights reserved.

45 CFR Appendix A to Part 96 - Uniform Definitions of Services

Code of Federal Regulations, 2010 CFR

2010-10-01

...-hour day. Component services or activities may include opportunity for social interaction... activities for children, recreation, meals and snacks, transportation, health support services, social... those educational, comprehensive medical or social services or activities which enable individuals...

Distributed Virtual System (DIVIRS) Project

NASA Technical Reports Server (NTRS)

Schorr, Herbert; Neuman, B. Clifford

1993-01-01

As outlined in our continuation proposal 92-ISI-50R (revised) on contract NCC 2-539, we are (1) developing software, including a system manager and a job manager, that will manage available resources and that will enable programmers to program parallel applications in terms of a virtual configuration of processors, hiding the mapping to physical nodes; (2) developing communications routines that support the abstractions implemented in item one; (3) continuing the development of file and information systems based on the virtual system model; and (4) incorporating appropriate security measures to allow the mechanisms developed in items 1 through 3 to be used on an open network. The goal throughout our work is to provide a uniform model that can be applied to both parallel and distributed systems. We believe that multiprocessor systems should exist in the context of distributed systems, allowing them to be more easily shared by those that need them. Our work provides the mechanisms through which nodes on multiprocessors are allocated to jobs running within the distributed system and the mechanisms through which files needed by those jobs can be located and accessed.

Evaluation of stereo-array isotope labeling (SAIL) patterns for automated structural analysis of proteins with CYANA.

PubMed

Ikeya, Teppei; Terauchi, Tsutomu; Güntert, Peter; Kainosho, Masatsune

2006-07-01

Recently we have developed the stereo-array isotope labeling (SAIL) technique to overcome the conventional molecular size limitation in NMR protein structure determination by employing complete stereo- and regiospecific patterns of stable isotopes. SAIL sharpens signals and simplifies spectra without the loss of requisite structural information, thus making large classes of proteins newly accessible to detailed solution structure determination. The automated structure calculation program CYANA can efficiently analyze SAIL-NOESY spectra and calculate structures without manual analysis. Nevertheless, the original SAIL method might not be capable of determining the structures of proteins larger than 50 kDa or membrane proteins, for which the spectra are characterized by many broadened and overlapped peaks. Here we have carried out simulations of new SAIL patterns optimized for minimal relaxation and overlap, to evaluate the combined use of SAIL and CYANA for solving the structures of larger proteins and membrane proteins. The modified approach reduces the number of peaks to nearly half of that observed with uniform labeling, while still yielding well-defined structures and is expected to enable NMR structure determinations of these challenging systems.

A Curved Image-Plate Detector System for High-Resolution Synchrotron X-ray Diffraction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sarin, P.; Haggerty, R; Yoon, W

2009-01-01

The developed curved image plate (CIP) is a one-dimensional detector which simultaneously records high-resolution X-ray diffraction (XRD) patterns over a 38.7 2{theta} range. In addition, an on-site reader enables rapid extraction, transfer and storage of X-ray intensity information in {le}30 s, and further qualifies this detector to study kinetic processes in materials science. The CIP detector can detect and store X-ray intensity information linearly proportional to the incident photon flux over a dynamical range of about five orders of magnitude. The linearity and uniformity of the CIP detector response is not compromised in the unsaturated regions of the image plate,more » regardless of saturation in another region. The speed of XRD data acquisition together with excellent resolution afforded by the CIP detector is unique and opens up wide possibilities in materials research accessible through X-ray diffraction. This article presents details of the basic features, operation and performance of the CIP detector along with some examples of applications, including high-temperature XRD.« less

DIstributed VIRtual System (DIVIRS) project

NASA Technical Reports Server (NTRS)

Schorr, Herbert; Neuman, B. Clifford

1994-01-01

As outlined in our continuation proposal 92-ISI-. OR (revised) on NASA cooperative agreement NCC2-539, we are (1) developing software, including a system manager and a job manager, that will manage available resources and that will enable programmers to develop and execute parallel applications in terms of a virtual configuration of processors, hiding the mapping to physical nodes; (2) developing communications routines that support the abstractions implemented in item one; (3) continuing the development of file and information systems based on the Virtual System Model; and (4) incorporating appropriate security measures to allow the mechanisms developed in items 1 through 3 to be used on an open network. The goal throughout our work is to provide a uniform model that can be applied to both parallel and distributed systems. We believe that multiprocessor systems should exist in the context of distributed systems, allowing them to be more easily shared by those that need them. Our work provides the mechanisms through which nodes on multiprocessors are allocated to jobs running within the distributed system and the mechanisms through which files needed by those jobs can be located and accessed.

DIstributed VIRtual System (DIVIRS) project

NASA Technical Reports Server (NTRS)

Schorr, Herbert; Neuman, Clifford B.

1995-01-01

As outlined in our continuation proposal 92-ISI-50R (revised) on NASA cooperative agreement NCC2-539, we are (1) developing software, including a system manager and a job manager, that will manage available resources and that will enable programmers to develop and execute parallel applications in terms of a virtual configuration of processors, hiding the mapping to physical nodes; (2) developing communications routines that support the abstractions implemented in item one; (3) continuing the development of file and information systems based on the Virtual System Model; and (4) incorporating appropriate security measures to allow the mechanisms developed in items 1 through 3 to be used on an open network. The goal throughout our work is to provide a uniform model that can be applied to both parallel and distributed systems. We believe that multiprocessor systems should exist in the context of distributed systems, allowing them to be more easily shared by those that need them. Our work provides the mechanisms through which nodes on multiprocessors are allocated to jobs running within the distributed system and the mechanisms through which files needed by those jobs can be located and accessed.

Distributed Virtual System (DIVIRS) project

NASA Technical Reports Server (NTRS)

Schorr, Herbert; Neuman, B. Clifford

1993-01-01

As outlined in the continuation proposal 92-ISI-50R (revised) on NASA cooperative agreement NCC 2-539, the investigators are developing software, including a system manager and a job manager, that will manage available resources and that will enable programmers to develop and execute parallel applications in terms of a virtual configuration of processors, hiding the mapping to physical nodes; developing communications routines that support the abstractions implemented; continuing the development of file and information systems based on the Virtual System Model; and incorporating appropriate security measures to allow the mechanisms developed to be used on an open network. The goal throughout the work is to provide a uniform model that can be applied to both parallel and distributed systems. The authors believe that multiprocessor systems should exist in the context of distributed systems, allowing them to be more easily shared by those that need them. The work provides the mechanisms through which nodes on multiprocessors are allocated to jobs running within the distributed system and the mechanisms through which files needed by those jobs can be located and accessed.

Simple and strong: twisted silver painted nylon artificial muscle actuated by Joule heating

NASA Astrophysics Data System (ADS)

Mirvakili, Seyed M.; Rafie Ravandi, Ali; Hunter, Ian W.; Haines, Carter S.; Li, Na; Foroughi, Javad; Naficy, Sina; Spinks, Geoffrey M.; Baughman, Ray H.; Madden, John D. W.

2014-03-01

Highly oriented nylon and polyethylene fibres shrink in length when heated and expand in diameter. By twisting and then coiling monofilaments of these materials to form helical springs, the anisotropic thermal expansion has recently been shown to enable tensile actuation of up to 49% upon heating. Joule heating, by passing a current through a conductive coating on the surface of the filament, is a convenient method of controlling actuation. In previously reported work this has been done using highly flexible carbon nanotube sheets or commercially available silver coated fibres. In this work silver paint is used as the Joule heating element at the surface of the muscle. Up to 29% linear actuation is observed with energy and power densities reaching 840 kJ m-3 (528 J kg-1) and 1.1 kW kg-1 (operating at 0.1 Hz, 4% strain, 1.4 kg load). This simple coating method is readily accessible and can be applied to any polymer filament. Effective use of this technique relies on uniform coating to avoid temperature gradients.

Neuroscience imaging enabled by new highly tunable and high peak power femtosecond lasers

NASA Astrophysics Data System (ADS)

Hakulinen, T.; Klein, J.

2017-02-01

Neuroscience applications benefit from recent developments in industrial femtosecond laser technology. New laser sources provide several megawatts of peak power at wavelength of 1040 nm, which enables simultaneous optogenetics photoactivation of tens or even hundreds of neurons using red shifted opsins. Another recent imaging trend is to move towards longer wavelengths, which would enable access to deeper layers of tissue due to lower scattering and lower absorption in the tissue. Femtosecond lasers pumping a non-collinear optical parametric amplifier (NOPA) enable the access to longer wavelengths with high peak powers. High peak powers of >10 MW at 1300 nm and 1700 nm allow effective 3-photon excitation of green and red shifted calcium indicators respectively and access to deeper, sub-cortex layers of the brain. Early results include in vivo detection of spontaneous activity in hippocampus within an intact mouse brain, where neurons express GCaMP6 activated in a 3-photon process at 1320 nm.

The Master Lens Database and The Orphan Lenses Project

NASA Astrophysics Data System (ADS)

Moustakas, Leonidas

2012-10-01

Strong gravitational lenses are uniquely suited for the study of dark matter structure and substructure within massive halos of many scales, act as gravitational telescopes for distant faint objects, and can give powerful and competitive cosmological constraints. While hundreds of strong lenses are known to date, spanning five orders of magnitude in mass scale, thousands will be identified this decade. To fully exploit the power of these objects presently, and in the near future, we are creating the Master Lens Database. This is a clearinghouse of all known strong lens systems, with a sophisticated and modern database of uniformly measured and derived observational and lens-model derived quantities, using archival Hubble data across several instruments. This Database enables new science that can be done with a comprehensive sample of strong lenses. The operational goal of this proposal is to develop the process and the code to semi-automatically stage Hubble data of each system, create appropriate masks of the lensing objects and lensing features, and derive gravitational lens models, to provide a uniform and fairly comprehensive information set that is ingested into the Database. The scientific goal for this team is to use the properties of the ensemble of lenses to make a new study of the internal structure of lensing galaxies, and to identify new objects that show evidence of strong substructure lensing, for follow-up study. All data, scripts, masks, model setup files, and derived parameters, will be public, and free. The Database will be accessible online and through a sophisticated smartphone application, which will also be free.

Enhanced sequencing coverage with digital droplet multiple displacement amplification

PubMed Central

Sidore, Angus M.; Lan, Freeman; Lim, Shaun W.; Abate, Adam R.

2016-01-01

Sequencing small quantities of DNA is important for applications ranging from the assembly of uncultivable microbial genomes to the identification of cancer-associated mutations. To obtain sufficient quantities of DNA for sequencing, the small amount of starting material must be amplified significantly. However, existing methods often yield errors or non-uniform coverage, reducing sequencing data quality. Here, we describe digital droplet multiple displacement amplification, a method that enables massive amplification of low-input material while maintaining sequence accuracy and uniformity. The low-input material is compartmentalized as single molecules in millions of picoliter droplets. Because the molecules are isolated in compartments, they amplify to saturation without competing for resources; this yields uniform representation of all sequences in the final product and, in turn, enhances the quality of the sequence data. We demonstrate the ability to uniformly amplify the genomes of single Escherichia coli cells, comprising just 4.7 fg of starting DNA, and obtain sequencing coverage distributions that rival that of unamplified material. Digital droplet multiple displacement amplification provides a simple and effective method for amplifying minute amounts of DNA for accurate and uniform sequencing. PMID:26704978

Help seeking in older Asian people with dementia in Melbourne: using the Cultural Exchange Model to explore barriers and enablers.

PubMed

Haralambous, Betty; Dow, Briony; Tinney, Jean; Lin, Xiaoping; Blackberry, Irene; Rayner, Victoria; Lee, Sook-Meng; Vrantsidis, Freda; Lautenschlager, Nicola; Logiudice, Dina

2014-03-01

The prevalence of dementia is increasing in Australia. Limited research is available on access to Cognitive Dementia and Memory Services (CDAMS) for people with dementia from Culturally and Linguistically Diverse (CALD) communities. This study aimed to determine the barriers and enablers to accessing CDAMS for people with dementia and their families of Chinese and Vietnamese backgrounds. Consultations with community members, community workers and health professionals were conducted using the "Cultural Exchange Model" framework. For carers, barriers to accessing services included the complexity of the health system, lack of time, travel required to get to services, language barriers, interpreters and lack of knowledge of services. Similarly, community workers and health professionals identified language, interpreters, and community perceptions as key barriers to service access. Strategies to increase knowledge included providing information via radio, printed material and education in community group settings. The "Cultural Exchange Model" enabled engagement with and modification of the approaches to meet the needs of the targeted CALD communities.

47 CFR 54.601 - Eligibility.

Code of Federal Regulations, 2011 CFR

2011-10-01

...). (2) Internet access and limited toll-free access to internet. (i) For purposes of this subpart, eligible Internet access is an information service that enables rural health care providers to post their...) Internet access shall be eligible for universal service support under § 54.621(a). (iii) Limited toll-free...

7 CFR 1739.3 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... terrestrial technology having the capacity to provide transmission facilities that enable subscribers of the...) Computer Access Points and wireless access, that is used for the purposes of providing free access to and..., and after normal working hours and on Saturdays or Sunday. Computer Access Point means a new computer...

Providing Data Access for Interdisciplinary Research

NASA Astrophysics Data System (ADS)

Hooper, R. P.; Couch, A.

2012-12-01

Developing an interdisciplinary understanding of human and environmental interactions with water requires access to a variety of data kinds collected by various organizations. The CUAHSI Hydrologic Information System (HIS) is a standards-based, services-oriented architecture designed for time-series data. Such data represents an important type of data in water studies. Through the efforts of HIS, a standard transmission language, WaterML2, has been adopted by the Open Geospatial Consortium and is under consideration by the World Meteorologic Organization as an international standards. Web services have also been developed to retrieve data and metadata. HIS is completed with a metadata catalog, hosted by San Diego Supercomputing Center, which indexes more than 20 million time series provided from over 90 different services. This catalog is supported through a hierarchically organized controlled vocabulary that is open for community input and mediation. Data publishers include federal agencies, universities, state agencies, and non-profit organizations such as watershed associations. Accessing data from such a broad spectrum of sources through a uniform service standard promises to truly transform the way in which hydrologic research is done. CUAHSI HIS is a large-scale prototype at this time, but a proposal is under consideration by the National Science Foundation to operationalize HIS through a data facility, tentatively called the CUAHSI Water Data Center. Establishing HIS is an important step to enable research into human-environment interactions with water, but it is only one step. Other data structures will need to be made accessible and interoperable to support this research. Some data—such as two-dimensional GIS coverages—already have widely used standards for transmission and sharing. The US Federal government has long operated a clearinghouse for federal geographic data that is now being augmented with other services such as ArcGIS OnLine. Other data, such as gridded data, have standard storage formats (e.g., netCDF) but its native format is not convenient for water research. Some progress has been made to "transpose" these data sets from gridded data to a grid of virtual gages with time series. Such a format is more convenient for research of a limited spatial extent through time. Advances in relational data base structure now make it possible to serve very large data sets, such as radar-based precipitation grids, through HIS. Expanding the use of a standards-based services-oriented architecture will enable interdisciplinary research to proceed far more rapidly by putting data onto scientists' computers with a fraction of the effort previously required.

An enhanced two-step floating catchment area (E2SFCA) method for measuring spatial accessibility to primary care physicians.

PubMed

Luo, Wei; Qi, Yi

2009-12-01

This paper presents an enhancement of the two-step floating catchment area (2SFCA) method for measuring spatial accessibility, addressing the problem of uniform access within the catchment by applying weights to different travel time zones to account for distance decay. The enhancement is proved to be another special case of the gravity model. When applying this enhanced 2SFCA (E2SFCA) to measure the spatial access to primary care physicians in a study area in northern Illinois, we find that it reveals spatial accessibility pattern that is more consistent with intuition and delineates more spatially explicit health professional shortage areas. It is easy to implement in GIS and straightforward to interpret.

Young Children's Everyday Concepts of the Internet: A Platform for Cyber-Safety Education in the Early Years

ERIC Educational Resources Information Center

Edwards, Susan; Nolan, Andrea; Henderson, Michael; Mantilla, Ana; Plowman, Lydia; Skouteris, Helen

2018-01-01

Young children from around the world are accessing the internet in ever increasing numbers. The rapid increase in internet activity by children aged 4-5 years in particular is due to the ease access enabled them by touchscreen internet-enabled tablet technologies. With young children now online, often independently of adult supervision, the need…

Lowering the Barrier to Cross-Disciplinary Scientific Data Access via a Brokering Service Built Around a Unified Data Model

NASA Astrophysics Data System (ADS)

Lindholm, D. M.; Wilson, A.

2012-12-01

The steps many scientific data users go through to use data (after discovering it) can be rather tedious, even when dealing with datasets within their own discipline. Accessing data across domains often seems intractable. We present here, LaTiS, an Open Source brokering solution that bridges the gap between the source data and the user's code by defining a unified data model plus a plugin framework for "adapters" to read data from their native source, "filters" to perform server side data processing, and "writers" to output any number of desired formats or streaming protocols. A great deal of work is being done in the informatics community to promote multi-disciplinary science with a focus on search and discovery based on metadata - information about the data. The goal of LaTiS is to go that last step to provide a uniform interface to read the dataset into computer programs and other applications once it has been identified. The LaTiS solution for integrating a wide variety of data models is to return to mathematical fundamentals. The LaTiS data model emphasizes functional relationships between variables. For example, a time series of temperature measurements can be thought of as a function that maps a time to a temperature. With just three constructs: "Scalar" for a single variable, "Tuple" for a collection of variables, and "Function" to represent a set of independent and dependent variables, the LaTiS data model can represent most scientific datasets at a low level that enables uniform data access. Higher level abstractions can be built on top of the basic model to add more meaningful semantics for specific user communities. LaTiS defines its data model in terms of the Unified Modeling Language (UML). It also defines a very thin Java Interface that can be implemented by numerous existing data interfaces (e.g. NetCDF-Java) such that client code can access any dataset via the Java API, independent of the underlying data access mechanism. LaTiS also provides a reference implementation of the data model and server framework (with a RESTful service interface) in the Scala programming language. Scala can be thought of as the next generation of Java. It runs on the Java Virtual Machine and can directly use Java code. Scala improves upon Java's object-oriented capabilities and adds support for functional programming paradigms which are particularly well suited for scientific data analysis. The Scala implementation of LaTiS can be thought of as a Domain Specific Language (DSL) which presents an API that better matches the semantics of the problems scientific data users are trying to solve. Instead of working with bytes, ints, or arrays, the data user can directly work with data as "time series" or "spectra". LaTiS provides many layers of abstraction with which users can interact to support a wide variety of data access and analysis needs.

10 CFR 600.144 - Procurement procedures.

Code of Federal Regulations, 2010 CFR

2010-01-01

... integrity, record of past performance, financial and technical resources or accessibility to other necessary... DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES Uniform Administrative... practicable, of technical requirements in terms of functions to be performed or performance required...

Lead isotope data bank; 2,624 samples and analyses cited

USGS Publications Warehouse

Doe, Bruce R.

1976-01-01

The Lead Isotope Data Bank (LIDB) was initiated to facilitate plotting data. Therefore, the Bank reflects data most often used in plotting rather than comprises a comprehensive tabulation of lead isotope data. Up until now, plotting was done using card decks processed by computer with tapes plotted by a Gerber plotter and more recently a CRT using a batch mode. Lack of a uniform format for sample identification was not a great impediment. With increase in the size of the bank, hand sorting is becoming prohibitive and ·plans are underway to put the bank into a uniform format on DISK with a card backup so that it may be accessed by use of IRIS on the DECK 10 computer at the U.S.G.S. facility in Denver. Plots will be constructed on a CRT. Entry of the bank into the IRIS accessing program is scheduled for completion in FY 1976

OpenMSI: A High-Performance Web-Based Platform for Mass Spectrometry Imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rubel, Oliver; Greiner, Annette; Cholia, Shreyas

Mass spectrometry imaging (MSI) enables researchers to directly probe endogenous molecules directly within the architecture of the biological matrix. Unfortunately, efficient access, management, and analysis of the data generated by MSI approaches remain major challenges to this rapidly developing field. Despite the availability of numerous dedicated file formats and software packages, it is a widely held viewpoint that the biggest challenge is simply opening, sharing, and analyzing a file without loss of information. Here we present OpenMSI, a software framework and platform that addresses these challenges via an advanced, high-performance, extensible file format and Web API for remote data accessmore » (http://openmsi.nersc.gov). The OpenMSI file format supports storage of raw MSI data, metadata, and derived analyses in a single, self-describing format based on HDF5 and is supported by a large range of analysis software (e.g., Matlab and R) and programming languages (e.g., C++, Fortran, and Python). Careful optimization of the storage layout of MSI data sets using chunking, compression, and data replication accelerates common, selective data access operations while minimizing data storage requirements and are critical enablers of rapid data I/O. The OpenMSI file format has shown to provide >2000-fold improvement for image access operations, enabling spectrum and image retrieval in less than 0.3 s across the Internet even for 50 GB MSI data sets. To make remote high-performance compute resources accessible for analysis and to facilitate data sharing and collaboration, we describe an easy-to-use yet powerful Web API, enabling fast and convenient access to MSI data, metadata, and derived analysis results stored remotely to facilitate high-performance data analysis and enable implementation of Web based data sharing, visualization, and analysis.« less

GERLUMPH DATA RELEASE 1: HIGH-RESOLUTION COSMOLOGICAL MICROLENSING MAGNIFICATION MAPS AND eResearch TOOLS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vernardos, G.; Fluke, C. J.; Croton, D.

2014-03-01

As synoptic all-sky surveys begin to discover new multiply lensed quasars, the flow of data will enable statistical cosmological microlensing studies of sufficient size to constrain quasar accretion disk and supermassive black hole properties. In preparation for this new era, we are undertaking the GPU-Enabled, High Resolution cosmological MicroLensing parameter survey (GERLUMPH). We present here the GERLUMPH Data Release 1, which consists of 12,342 high resolution cosmological microlensing magnification maps and provides the first uniform coverage of the convergence, shear, and smooth matter fraction parameter space. We use these maps to perform a comprehensive numerical investigation of the mass-sheet degeneracy,more » finding excellent agreement with its predictions. We study the effect of smooth matter on microlensing induced magnification fluctuations. In particular, in the minima and saddle-point regions, fluctuations are enhanced only along the critical line, while in the maxima region they are always enhanced for high smooth matter fractions (≈0.9). We describe our approach to data management, including the use of an SQL database with a Web interface for data access and online analysis, obviating the need for individuals to download large volumes of data. In combination with existing observational databases and online applications, the GERLUMPH archive represents a fundamental component of a new microlensing eResearch cloud. Our maps and tools are publicly available at http://gerlumph.swin.edu.au/.« less

Standardizing intensive care device data to enable secondary usages.

PubMed

Ingenerf, Josef; Kock, Ann-Kristin; Poelker, Marcel; Seidl, Konrad; Zeplin, Georg; Mersmann, Stefan; Handels, Heinz

2012-01-01

To represent medical device observations in a format that is consumable by clinical software, standards like HL7v3 and ISO/IEEE 11073 should be used jointly. This is demonstrated in a project with Dräger Medical GmbH focusing on their Patient Data Management System (PDMS) in intensive care, called Integrated Care Manager (ICM). Patient and device data of interest should be mapped to suitable formats to enable data exchange and decision support. Instead of mapping device data to target formats bilaterally we use a generic HL7v3 Refined Message Information Model (RMIM) with device specific parts adapted to ISO/IEEE 11073 DIM. The generality of the underlying model (based on Yuksel et al. [1]) allows the flexible inclusion of IEEE 11073 conformant device models of interest on the one hand and the generation of needed artifacts for secondary usages on the other hand, e.g. HL7 V2 messages, HL7 CDA documents like the Personal Health Monitoring Report (PHMR) or web services. Hence, once the medical device data are obtained in the RMIM format, it can quite easily be transformed into HL7-based standard interfaces through XSL transformations because these interfaces all have their building blocks from the same RIM. From there data can be accessed uniformly, e.g. as needed by Dräger´s decision support system SmartCare [2] for automated control and optimization of weaning from mechanical ventilation.

The Organization of European Cancer Institute Pathobiology Working Group and its support of European biobanking infrastructures for translational cancer research.

PubMed

Riegman, Peter H J; de Jong, Bas W D; Llombart-Bosch, Antonio

2010-04-01

Today's translational cancer research increasingly depends on international multi-center studies. Biobanking infrastructure or comprehensive sample exchange platforms to enable networking of clinical cancer biobanks are instrumental to facilitate communication, uniform sample quality, and rules for exchange. The Organization of European Cancer Institutes (OECI) Pathobiology Working Group supports European biobanking infrastructure by maintaining the OECI-TuBaFrost exchange platform and organizing regular meetings. This platform originated from a European Commission project and is updated with knowledge from ongoing and new biobanking projects. This overview describes how European biobanking projects that have a large impact on clinical biobanking, including EuroBoNeT, SPIDIA, and BBMRI, contribute to the update of the OECI-TuBaFrost exchange platform. Combining the results of these European projects enabled the creation of an open (upon valid registration only) catalogue view of cancer biobanks and their available samples to initiate research projects. In addition, closed environments supporting active projects could be developed together with the latest views on quality, access rules, ethics, and law. With these contributions, the OECI Pathobiology Working Group contributes to and stimulates a professional attitude within biobanks at the European comprehensive cancer centers. Improving the fundamentals of cancer sample exchange in Europe stimulates the performance of large multi-center studies, resulting in experiments with the desired statistical significance outcome. With this approach, future innovation in cancer patient care can be realized faster and more reliably.

Utilizing Fission Technology to Enable Rapid and Affordable Access to any Point in the Solar System

NASA Technical Reports Server (NTRS)

Houts, Mike; Bonometti, Joe; Morton, Jeff; Hrbud, Ivana; Bitteker, Leo; VanDyke, Melissa; Godfroy, T.; Pedersen, K.; Dobson, C.; Patton, B.;

Addressing legal and policy barriers to male circumcision for adolescent boys in South Africa.

PubMed

Strode, A E; Toohey, J D; Slack, C M

2016-12-01

With millions of adolescents becoming infected with HIV globally, it is essential that barriers to much-needed interventions are reduced for at-risk adolescents. In this article we review the legal and policy framework in South Africa for adolescent access to male circumcision. We are of the view that the framework does confer protection for adolescent boys while enabling access to male circumcision; however, we identify ambiguities and tensions that exist between the Children's Act, regulations and national guidelines. We recommend reform to further enable access by this vulnerable group to this prevention modality.

AFSC Standardization Conference, 1553, 1589, 1750, 1760, Ada, November 18-20, 1980, Dayton Convention Center, Dayton, Ohio, Volume II. Proceedings Standards,

DTIC Science & Technology

1980-11-01

4006 DMAE Direct Memory Access Enable: ’Ibis command enables direct memory access (DMA). 4007 I)MAi) Direct Memory Access Disable: This command...72 DLI 72 DLR 72 DM 111 DMAD 30 DMAE 30 DMR 111 ONEG 103 DR 117 DS 104 OSAR 53 141 373 ’., M1L-STD-1750A (USAF) 2 July 1980 OSBI 29 OSCR 54 OSIC 48...in 4.7.7, the connectors shall show no defects detrimental to the operation of the connectors and shall A-7 461 -meet the subsequent test requirements

Building a Generic Virtual Research Environment Framework for Multiple Earth and Space Science Domains and a Diversity of Users.

NASA Astrophysics Data System (ADS)

Wyborn, L. A.; Fraser, R.; Evans, B. J. K.; Friedrich, C.; Klump, J. F.; Lescinsky, D. T.

2017-12-01

Virtual Research Environments (VREs) are now part of academic infrastructures. Online research workflows can be orchestrated whereby data can be accessed from multiple external repositories with processing taking place on public or private clouds, and centralised supercomputers using a mixture of user codes, and well-used community software and libraries. VREs enable distributed members of research teams to actively work together to share data, models, tools, software, workflows, best practices, infrastructures, etc. These environments and their components are increasingly able to support the needs of undergraduate teaching. External to the research sector, they can also be reused by citizen scientists, and be repurposed for industry users to help accelerate the diffusion and hence enable the translation of research innovations. The Virtual Geophysics Laboratory (VGL) in Australia was started in 2012, built using a collaboration between CSIRO, the National Computational Infrastructure (NCI) and Geoscience Australia, with support funding from the Australian Government Department of Education. VGL comprises three main modules that provide an interface to enable users to first select their required data; to choose a tool to process that data; and then access compute infrastructure for execution. VGL was initially built to enable a specific set of researchers in government agencies access to specific data sets and a limited number of tools. Over the years it has evolved into a multi-purpose Earth science platform with access to an increased variety of data (e.g., Natural Hazards, Geochemistry), a broader range of software packages, and an increasing diversity of compute infrastructures. This expansion has been possible because of the approach to loosely couple data, tools and compute resources via interfaces that are built on international standards and accessed as network-enabled services wherever possible. Built originally for researchers that were not fussy about general usability, increasing emphasis on User Interfaces (UIs) and stability will lead to increased uptake in the education and industry sectors. Simultaneously, improvements are being added to facilitate access to data and tools by experienced researchers who want direct access to both data and flexible workflows.

What are the emerging features of community health insurance schemes in East Africa?

PubMed Central

Basaza, Robert; Pariyo, George; Criel, Bart

2009-01-01

Background The three East African countries of Uganda, Tanzania, and Kenya are characterized by high poverty levels, population growth rates, prevalence of HIV/AIDS, under-funding of the health sector, poor access to quality health care, and small health insurance coverage. Tanzania and Kenya have user-fees whereas Uganda abolished user-fees in public-owned health units. Objective To provide comparative description of community health insurance (CHI) schemes in three East African countries of Uganda, Tanzania, and Kenya and thereafter provide a basis for future policy research for development of CHI schemes. Methods An analytical grid of 10 distinctive items pertaining to the nature of CHI schemes was developed so as to have a uniform lens of comparing country situations of CHI. Results and conclusions The majority of the schemes have been in existence for a relatively short time of less than 10 years and their number remains small. There is need for further research to identify what is the mix and weight of factors that cause people to refrain from joining schemes. Specific issues that could also be addressed in subsequent studies are whether the current schemes provide financial protection, increase access to quality of care and impact on the equity of health services financing and delivery. On the basis of this knowledge, rational policy decisions can be taken. The governments thereafter could consider an option of playing more roles in advocacy, paying for the poorest, and developing an enabling policy and legal framework. PMID:22312207

3D Printed Fluidic Hardware for DNA Assembly

DTIC Science & Technology

2015-04-10

A3909 stepper motor driver, were soldered onto the milled circuit board (Supplementary Figure 8). Custom Arduino - based firmware was written to take...initiatives such as the FabLab Foundation10. Access to digital fabrication tools and open electronics, such as Arduino and Raspberry Pi, enables access to...hardware for assembly of DNA- based genetic circuits. Solid-phase DNA synthesis has declined in price, enabling researchers to routinely design and

Ontology-based geospatial data query and integration

USGS Publications Warehouse

Zhao, T.; Zhang, C.; Wei, M.; Peng, Z.-R.

2008-01-01

Geospatial data sharing is an increasingly important subject as large amount of data is produced by a variety of sources, stored in incompatible formats, and accessible through different GIS applications. Past efforts to enable sharing have produced standardized data format such as GML and data access protocols such as Web Feature Service (WFS). While these standards help enabling client applications to gain access to heterogeneous data stored in different formats from diverse sources, the usability of the access is limited due to the lack of data semantics encoded in the WFS feature types. Past research has used ontology languages to describe the semantics of geospatial data but ontology-based queries cannot be applied directly to legacy data stored in databases or shapefiles, or to feature data in WFS services. This paper presents a method to enable ontology query on spatial data available from WFS services and on data stored in databases. We do not create ontology instances explicitly and thus avoid the problems of data replication. Instead, user queries are rewritten to WFS getFeature requests and SQL queries to database. The method also has the benefits of being able to utilize existing tools of databases, WFS, and GML while enabling query based on ontology semantics. ?? 2008 Springer-Verlag Berlin Heidelberg.

Automated support tool for variable rate irrigation prescriptions

USDA-ARS?s Scientific Manuscript database

Variable rate irrigation (VRI) enables center pivot management to better meet non-uniform water and fertility needs. This is accomplished through correctly matching system water application with spatial and temporal variability within the field. A computer program was modified to accommodate GIS dat...

Development of uniform standards for allowable lane closure : final report, September 2008.

DOT National Transportation Integrated Search

2008-09-01

Procedures for determining allowable lane closure hours to perform maintenance, construction, resurfacing, regional permit and major access permit work on the state highway system were evaluated. The current process involves the collection of traffic...

Enabling High Performance Instruments for UV Astronomy and Space Exploration with ALD

NASA Technical Reports Server (NTRS)

Greer, F.; Hoenk, M. E.; Jones, T. J.; Jacquot, B. C.; Monacos, S.; Nikzad, S.; Hamden, E.; Schiminovich, D.

2011-01-01

Benefits of Atomic Layer Deposition (ALD) for UV instruments and application are: (1) Ultrathin, highly conformal, and uniform films over arbitrarily large surface area (2) High quality films (density, roughness, conductivity, etc.) (3) Angstrom level control of stoichiometry, interfaces, and surface properties (3a) Multilayer nanolaminates/nanocomposites (3b) Low temperature surface engineering UV flight applications enabled by ALD. (1) Anti -reflective coatings/Mirrors/Filters/Optics for UV/Vis/NIR Detectors (2) Surface Passivation for III -N detectors

A Nonfullerene Small Molecule Acceptor with 3D Interlocking Geometry Enabling Efficient Organic Solar Cells.

PubMed

Lee, Jaewon; Singh, Ranbir; Sin, Dong Hun; Kim, Heung Gyu; Song, Kyu Chan; Cho, Kilwon

2016-01-06

A new 3D nonfullerene small-molecule acceptor is reported. The 3D interlocking geometry of the small-molecule acceptor enables uniform molecular conformation and strong intermolecular connectivity, facilitating favorable nanoscale phase separation and electron charge transfer. By employing both a novel polymer donor and a nonfullerene small-molecule acceptor in the solution-processed organic solar cells, a high-power conversion efficiency of close to 6% is demonstrated. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Improvement of Predictive Ability by Uniform Coverage of the Target Genetic Space

PubMed Central

Bustos-Korts, Daniela; Malosetti, Marcos; Chapman, Scott; Biddulph, Ben; van Eeuwijk, Fred

2016-01-01

Genome-enabled prediction provides breeders with the means to increase the number of genotypes that can be evaluated for selection. One of the major challenges in genome-enabled prediction is how to construct a training set of genotypes from a calibration set that represents the target population of genotypes, where the calibration set is composed of a training and validation set. A random sampling protocol of genotypes from the calibration set will lead to low quality coverage of the total genetic space by the training set when the calibration set contains population structure. As a consequence, predictive ability will be affected negatively, because some parts of the genotypic diversity in the target population will be under-represented in the training set, whereas other parts will be over-represented. Therefore, we propose a training set construction method that uniformly samples the genetic space spanned by the target population of genotypes, thereby increasing predictive ability. To evaluate our method, we constructed training sets alongside with the identification of corresponding genomic prediction models for four genotype panels that differed in the amount of population structure they contained (maize Flint, maize Dent, wheat, and rice). Training sets were constructed using uniform sampling, stratified-uniform sampling, stratified sampling and random sampling. We compared these methods with a method that maximizes the generalized coefficient of determination (CD). Several training set sizes were considered. We investigated four genomic prediction models: multi-locus QTL models, GBLUP models, combinations of QTL and GBLUPs, and Reproducing Kernel Hilbert Space (RKHS) models. For the maize and wheat panels, construction of the training set under uniform sampling led to a larger predictive ability than under stratified and random sampling. The results of our methods were similar to those of the CD method. For the rice panel, all training set construction methods led to similar predictive ability, a reflection of the very strong population structure in this panel. PMID:27672112

Uniform standards for genome databases in forest and fruit trees

USDA-ARS?s Scientific Manuscript database

TreeGenes and tfGDR serve the international forestry and fruit tree genomics research communities, respectively. These databases hold similar sequence data and provide resources for the submission and recovery of this information in order to enable comparative genomics research. Large-scale genotype...

77 FR 30586 - Uniform Relocation Assistance and Real Property Acquisition for Federal and Federally Assisted...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-23

...., Monday through Friday, except Federal holidays. SUPPLEMENTARY INFORMATION: Electronic Access An... 1500 1650 150 500 100 Vermont 400 550 650 850 1000 1100 1200 1300 150 300 75 Virgin Islands 500 700 850...

The Fight Against UCITA.

ERIC Educational Resources Information Center

Neal, James G.

2000-01-01

Discusses objections in the library community to the Uniform Computer Information Transactions Act (UCITA), a legal framework being considered by state governments regarding computer information, transactions, and software. Topics include copyright issues; user needs for access to information; license agreements; and costs that may prevent…

Enabling Virtual Access to Latin-American Southern Observatories

NASA Astrophysics Data System (ADS)

Filippi, G.

2010-12-01

EVALSO (Enabling Virtual Access to Latin-American Southern Observatories) is an international consortium of nine astronomical organisations and research network operators, part-funded under the European Commission FP7, to create and exploit high-speed bandwidth connections to South American observatories. A brief description of the project is presented. The EVALSO Consortium inaugurated a fibre link between the Paranal Observatory and international networks on 4 November 2010 capable of 10 Gigabit per second.

Access to Education with Online Learning and Open Educational Resources: Can They Close the Gap?

ERIC Educational Resources Information Center

Geith, Christine; Vignare, Karen

2008-01-01

One of the key concepts in the right to education is access: access to the means to fully develop as human beings as well as access to the means to gain skills, knowledge and credentials. This is an important perspective through which to examine the solutions to access enabled by Open Educational Resources (OER) and online learning. The authors…

Autonomy and Housing Accessibility Among Powered Mobility Device Users

PubMed Central

Brandt, Åse; Lexell, Eva Månsson; Iwarsson, Susanne

2015-01-01

OBJECTIVE. To describe environmental barriers, accessibility problems, and powered mobility device (PMD) users’ autonomy indoors and outdoors; to determine the home environmental barriers that generated the most housing accessibility problems indoors, at entrances, and in the close exterior surroundings; and to examine personal factors and environmental components and their association with indoor and outdoor autonomy. METHOD. This cross-sectional study was based on data collected from a sample of 48 PMD users with a spinal cord injury (SCI) using the Impact of Participation and Autonomy and the Housing Enabler instruments. Descriptive statistics and logistic regression were used. RESULTS. More years living with SCI predicted less restriction in autonomy indoors, whereas more functional limitations and accessibility problems related to entrance doors predicted more restriction in autonomy outdoors. CONCLUSION. To enable optimized PMD use, practitioners must pay attention to the relationship between client autonomy and housing accessibility problems. PMID:26356666

Globalising Accessibility: Drawing on the Experiences of Developed Countries to Enable the Participation of Disabled People in Zambia

ERIC Educational Resources Information Center

Banda-Chalwe, Martha; Nitz, Jennifer C.; de Jonge, Desleigh

2012-01-01

This paper explores the accessibility situation in a developing country such as Zambia. The global view of accessibility for disabled people is provided to examine the accessibility situation in developed and developing countries, highlighting the role of the environment in achieving rights for disabled people. Recognition of disability rights…

Enabling Remote Access to Fieldwork: Gaining Insight into the Pedagogic Effectiveness of "Direct" and "Remote" Field Activities

ERIC Educational Resources Information Center

Stokes, Alison; Collins, Trevor; Maskall, John; Lea, John; Lunt, Paul; Davies, Sarah

2012-01-01

This study considers the pedagogical effectiveness of remote access to fieldwork locations. Forty-one students from across the GEES disciplines (geography, earth and environmental sciences) undertook a fieldwork exercise, supported by two lecturers. Twenty students accessed the field site directly and the remainder accessed the site remotely using…

Non-Uniform Thickness Electroactive Device

NASA Technical Reports Server (NTRS)

Su, Ji (Inventor); Harrison, Joycelyn S. (Inventor)

2006-01-01

An electroactive device comprises at least two layers of material, wherein at least one layer is an electroactive material and wherein at least one layer is of non-uniform thickness. The device can be produced in various sizes, ranging from large structural actuators to microscale or nanoscale devices. The applied voltage to the device in combination with the non-uniform thickness of at least one of the layers (electroactive and/or non-electroactive) controls the contour of the actuated device. The effective electric field is a mathematical function of the local layer thickness. Therefore, the local strain and the local bending/ torsion curvature are also a mathematical function of the local thickness. Hence the thinnest portion of the actuator offers the largest bending and/or torsion response. Tailoring of the layer thicknesses can enable complex motions to be achieved.

Driving Chemical Reactions in Plasmonic Nanogaps with Electrohydrodynamic Flow.

PubMed

Thrift, William J; Nguyen, Cuong Q; Darvishzadeh-Varcheie, Mahsa; Zare, Siavash; Sharac, Nicholas; Sanderson, Robert N; Dupper, Torin J; Hochbaum, Allon I; Capolino, Filippo; Abdolhosseini Qomi, Mohammad Javad; Ragan, Regina

2017-11-28

Nanoparticles from colloidal solution-with controlled composition, size, and shape-serve as excellent building blocks for plasmonic devices and metasurfaces. However, understanding hierarchical driving forces affecting the geometry of oligomers and interparticle gap spacings is still needed to fabricate high-density architectures over large areas. Here, electrohydrodynamic (EHD) flow is used as a long-range driving force to enable carbodiimide cross-linking between nanospheres and produces oligomers exhibiting sub-nanometer gap spacing over mm 2 areas. Anhydride linkers between nanospheres are observed via surface-enhanced Raman scattering (SERS) spectroscopy. The anhydride linkers are cleavable via nucleophilic substitution and enable placement of nucleophilic molecules in electromagnetic hotspots. Atomistic simulations elucidate that the transient attractive force provided by EHD flow is needed to provide a sufficient residence time for anhydride cross-linking to overcome slow reaction kinetics. This synergistic analysis shows assembly involves an interplay between long-range driving forces increasing nanoparticle-nanoparticle interactions and probability that ligands are in proximity to overcome activation energy barriers associated with short-range chemical reactions. Absorption spectroscopy and electromagnetic full-wave simulations show that variations in nanogap spacing have a greater influence on optical response than variations in close-packed oligomer geometry. The EHD flow-anhydride cross-linking assembly method enables close-packed oligomers with uniform gap spacings that produce uniform SERS enhancement factors. These results demonstrate the efficacy of colloidal driving forces to selectively enable chemical reactions leading to future assembly platforms for large-area nanodevices.

Reproducible direct exposure environmental testing of metal-based magnetic media

NASA Technical Reports Server (NTRS)

Sides, Paul J.

1994-01-01

A flow geometry and flow rate for mixed flowing gas testing is proposed. Use of an impinging jet of humid polluted air can provide a uniform and reproducible exposure of coupons of metal-based magnetic media. Numerical analysis of the fluid flow and mass transfer in such as system has shown that samples confined within a distance equal to the nozzle radius on the surface of impingement are uniformly accessible to pollutants in the impinging gas phase. The critical factor is the nozzle height above the surface of impingement. In particular, the uniformity of exposure is less than plus/minus 2% for a volumetric flow rate of 1600 cm(exp 3)/minute total flow with the following specifications: For a one inch nozzle, the height of the nozzle opening above the stage should be 0.177 inches; for a 2 inch nozzle - 0.390 inches. Not only is the distribution uniform, but one can calculate the maximum delivery rate of pollutants to the samples for comparison with the observed deterioration.

Using QR codes to enable quick access to information in acute cancer care.

PubMed

Upton, Joanne; Olsson-Brown, Anna; Marshall, Ernie; Sacco, Joseph

2017-05-25

Quick access to toxicity management information ensures timely access to steroids/immunosuppressive treatment for cancer patients experiencing immune-related adverse events, thus reducing length of hospital stays or avoiding hospital admission entirely. This article discusses a project to add a QR (quick response) code to a patient-held immunotherapy alert card. As QR code generation is free and the immunotherapy clinical management algorithms were already publicly available through the trust's clinical network website, the costs of integrating a QR code into the alert card, after printing, were low, while the potential benefits are numerous. Patient-held alert cards are widely used for patients receiving anti-cancer treatment, and this established standard of care has been modified to enable rapid access of information through the incorporation of a QR code.

The Mission Accessible Near-Earth Object Survey (MANOS)

NASA Astrophysics Data System (ADS)

Moskovitz, N.; Manos Team

2014-07-01

Near-Earth objects (NEOs) are essential to understanding the origin of the Solar System through their compositional links to meteorites. As tracers of various regions within the Solar System they can provide insight to more distant, less accessible populations. Their relatively small sizes and complex dynamical histories make them excellent laboratories for studying ongoing Solar System processes such as space weathering, planetary encounters, and non-gravitational dynamics. Knowledge of their physical properties is essential to impact hazard assessment. Finally, the proximity of NEOs to Earth make them favorable targets for robotic and human exploration. However, in spite of their scientific importance, only the largest (km-scale) NEOs have been well studied and a representative sample of physical characteristics for sub-km NEOs does not exist. To address these issues we are conducting the Mission Accessible Near-Earth Object Survey (MANOS), a fully allocated multi-year survey of sub-km NEOs that will provide a large, uniform catalog of physical properties including light curves, spectra, and astrometry. From this comprehensive catalog, we will derive global properties of the NEO population, as well as identify individual targets that are of potential interest for exploration. We will accomplish these goals for approximately 500 mission-accessible NEOs across the visible and near-infrared ranges using telescope assets in both the northern and southern hemispheres. MANOS has been awarded large survey status by NOAO to employ Gemini-N, Gemini-S, SOAR, the Kitt Peak 4 m, and the CTIO 1.3 m. Access to additional facilities at Lowell Observatory (DCT 4.3 m, Perkins 72'', Hall 42'', LONEOS), the University of Hawaii, and the Catalina Sky Survey provide essential complements to this suite of telescopes. Targets for MANOS are selected based on three primary criteria: mission accessibility (i.e. Δ v < 7 km/s), size (H > 20), and observability. Our telescope assets allow us to obtain rotational light curves for objects down to V˜22, visible spectra down to V˜21, and near-IR spectra down to V˜19. MANOS primarily focuses on targets that are recently discovered. We employ a regular cadence of remote and queue observations to enable follow-up characterization within days or weeks after a target of interest is discovered. We will present a MANOS status report with an emphasis on noteworthy observations and ongoing efforts to achieve fully transparency by making target lists and data products publicly available online.

7 CFR 3015.23 - Microfilm.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Microfilm. 3015.23 Section 3015.23 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF AGRICULTURE UNIFORM FEDERAL ASSISTANCE REGULATIONS Record Retention and Access Requirements § 3015.23...

Modified rockfall catch fence Mayflower Creek - Detroit Dam : interim Report.

DOT National Transportation Integrated Search

1986-07-01

This experimental features project is located on the North Santiam Highway (#162) between Mayflower Creek and Detroit Dam, approximately 40 miles east of Salem. Here access is limited and the slope is non-uniform. To deal with the problem of falling ...

36 CFR 910.31 - High architectural quality.

Code of Federal Regulations, 2011 CFR

2011-07-01

... GENERAL GUIDELINES AND UNIFORM STANDARDS FOR URBAN PLANNING AND DESIGN OF DEVELOPMENT WITHIN THE... the best contemporary design and planning concepts. Great care and sensitivity must be shown in the... provisions for pedestrian and vehicular access. Special design considerations for each coordinated planning...

A Decentralized IT Architecture for Locating and Negotiating Access to Biobank Samples.

PubMed

Proynova, Rumyana; Alexandre, Diogo; Lablans, Martin; Van Enckevort, David; Mate, Sebastian; Eklund, Niina; Silander, Kaisa; Hummel, Michael; Holub, Petr; Ückert, Frank

2017-01-01

There is a need among researchers for the easy discoverability of biobank samples. Currently, there is no uniform way for finding samples and negotiate access. Instead, researchers have to communicate with each biobank separately. We present the architecture for the BBMRI-CS IT platform, whose goal is to facilitate sample location and access. We chose a decentral approach, which allows for strong data protection and provides the high flexibility needed in the highly heterogeneous landscape of European biobanks. This is the first implementation of a decentral search in the biobank field. With the addition of a Negotiator component, it also allows for easy communication and a follow-through of the lengthy approval process for accessing samples.

ACCESS: The Arizona-CfA-Catolica Exoplanet Spectroscopy Survey

NASA Astrophysics Data System (ADS)

Lopez-Morales, Mercedes; Apai, Daniel; Jordan, Andres; Espinoza, Nestor; Rackham, Benjamin; Fraine, Jonathan D.; Rodler, Florian; Lewis, Nikole; Fortney, Jonathan J.; Osip, David J.

2014-06-01

The Arizona-CfA-Catolica Exoplanet Spectroscopy Survey (ACCESS) is an international, multi-institutional consortium with members from the Harvard-Smithsonian CfA, the University of Arizona, Pontificia Universidad Catolica in Chile, MIT and UC Santa Cruz and the Carnegie Institution. ACCESS' goal is to observe about two dozen planets covering a wide range of mass, radius, atmospheric temperatures and energy irradiation levels, with two main scientific goals: 1) to obtain, for the first time, a uniform sample of visible transmission spectra of exoplanets, allowing the study of their atmospheric characteristics as a statistically significant sample, and 2) to mature the technique of ground-based observations of exoplanetary atmospheres for future observations of small planets. Here we describe ACCESS and its first science results.

High Tech and Library Access for People with Disabilities.

ERIC Educational Resources Information Center

Roatch, Mary A.

1992-01-01

Describes tools that enable people with disabilities to access print information, including optical character recognition, synthetic voice output, other input devices, Braille access devices, large print displays, television and video, TDD (Telecommunications Devices for the Deaf), and Telebraille. Use of technology by libraries to meet mandates…

GLIDE: a grid-based light-weight infrastructure for data-intensive environments

NASA Technical Reports Server (NTRS)

Mattmann, Chris A.; Malek, Sam; Beckman, Nels; Mikic-Rakic, Marija; Medvidovic, Nenad; Chrichton, Daniel J.

2005-01-01

The promise of the grid is that it will enable public access and sharing of immense amounts of computational and data resources among dynamic coalitions of individuals and institutions. However, the current grid solutions make several limiting assumptions that curtail their widespread adoption. To address these limitations, we present GLIDE, a prototype light-weight, data-intensive middleware infrastructure that enables access to the robust data and computational power of the grid on DREAM platforms.

Rise and Shock: Optimal Defibrillator Placement in a High-rise Building.

PubMed

Chan, Timothy C Y

2017-01-01

Out-of-hospital cardiac arrests (OHCA) in high-rise buildings experience lower survival and longer delays until paramedic arrival. Use of publicly accessible automated external defibrillators (AED) can improve survival, but "vertical" placement has not been studied. We aim to determine whether elevator-based or lobby-based AED placement results in shorter vertical distance travelled ("response distance") to OHCAs in a high-rise building. We developed a model of a single-elevator, n-floor high-rise building. We calculated and compared the average distance from AED to floor of arrest for the two AED locations. We modeled OHCA occurrences using floor-specific Poisson processes, the risk of OHCA on the ground floor (λ 1 ) and the risk on any above-ground floor (λ). The elevator was modeled with an override function enabling direct travel to the target floor. The elevator location upon override was modeled as a discrete uniform random variable. Calculations used the laws of probability. Elevator-based AED placement had shorter average response distance if the number of floors (n) in the building exceeded three quarters of the ratio of ground-floor OHCA risk to above-ground floor risk (λ 1 /λ) plus one half (n ≥ 3λ 1 /4λ + 0.5). Otherwise, a lobby-based AED had shorter average response distance. If OHCA risk on each floor was equal, an elevator-based AED had shorter average response distance. Elevator-based AEDs travel less vertical distance to OHCAs in tall buildings or those with uniform vertical risk, while lobby-based AEDs travel less vertical distance in buildings with substantial lobby, underground, and nearby street-level traffic and OHCA risk.

Parametric design of tri-axial nested Helmholtz coils

NASA Astrophysics Data System (ADS)

Abbott, Jake J.

2015-05-01

This paper provides an optimal parametric design for tri-axial nested Helmholtz coils, which are used to generate a uniform magnetic field with controllable magnitude and direction. Circular and square coils, both with square cross section, are considered. Practical considerations such as wire selection, wire-wrapping efficiency, wire bending radius, choice of power supply, and inductance and time response are included. Using the equations provided, a designer can quickly create an optimal set of custom coils to generate a specified field magnitude in the uniform-field region while maintaining specified accessibility to the central workspace. An example case study is included.

Parametric design of tri-axial nested Helmholtz coils.

PubMed

Abbott, Jake J

2015-05-01

This paper provides an optimal parametric design for tri-axial nested Helmholtz coils, which are used to generate a uniform magnetic field with controllable magnitude and direction. Circular and square coils, both with square cross section, are considered. Practical considerations such as wire selection, wire-wrapping efficiency, wire bending radius, choice of power supply, and inductance and time response are included. Using the equations provided, a designer can quickly create an optimal set of custom coils to generate a specified field magnitude in the uniform-field region while maintaining specified accessibility to the central workspace. An example case study is included.

Parametric design of tri-axial nested Helmholtz coils

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abbott, Jake J., E-mail: jake.abbott@utah.edu

This paper provides an optimal parametric design for tri-axial nested Helmholtz coils, which are used to generate a uniform magnetic field with controllable magnitude and direction. Circular and square coils, both with square cross section, are considered. Practical considerations such as wire selection, wire-wrapping efficiency, wire bending radius, choice of power supply, and inductance and time response are included. Using the equations provided, a designer can quickly create an optimal set of custom coils to generate a specified field magnitude in the uniform-field region while maintaining specified accessibility to the central workspace. An example case study is included.

The material of practice: the Canadian Nursing History Collection.

PubMed

Bates, Christina

2004-01-01

The Canadian Nursing History Collection is a special holding of over 1500 artifacts at the Canadian Museum of Civilization and the Canadian War Museum. The most significant of its kind, the collection includes uniforms, pins, diaries, instrument kits, and military medals. Researchers and the public will access the collection through an on-line catalogue, a major exhibition, and a book. The material culture of nursing represented by this collection provides nursing historians with a whole new body of evidence for insights into nursing history. The sample of hospital uniforms, from 1900 to the present, for example, raises new and theoretical approaches.

Barriers and enablers to healthcare access and use among Arabic-speaking and Caucasian English-speaking patients with type 2 diabetes mellitus: a qualitative comparative study

PubMed Central

Alzubaidi, H; Mc Namara, K; Browning, Colette; Marriott, J

2015-01-01

Objective The objective of this study was to explore the decision-making processes and associated barriers and enablers that determine access and use of healthcare services in Arabic-speaking and English-speaking Caucasian patients with diabetes in Australia. Study setting and design Face-to-face semistructured individual interviews and group interviews were conducted at various healthcare settings—diabetes outpatient clinics in 2 tertiary referral hospitals, 6 primary care practices and 10 community centres in Melbourne, Australia. Participants A total of 100 participants with type 2 diabetes mellitus were recruited into 2 groups: 60 Arabic-speaking and 40 English-speaking Caucasian. Data collection Interviews were audio-taped, translated into English when necessary, transcribed and coded thematically. Sociodemographic and clinical information was gathered using a self-completed questionnaire and medical records. Principal findings Only Arabic-speaking migrants intentionally delayed access to healthcare services when obvious signs of diabetes were experienced, missing opportunities to detect diabetes at an early stage. Four major barriers and enablers to healthcare access and use were identified: influence of significant other(s), unique sociocultural and religious beliefs, experiences with healthcare providers and lack of knowledge about healthcare services. Compared with Arabic-speaking migrants, English-speaking participants had no reluctance to access and use medical services when signs of ill-health appeared; their treatment-seeking behaviours were straightforward. Conclusions Arabic-speaking migrants appear to intentionally delay access to medical services even when symptomatic. Four barriers to health services access have been identified. Tailored interventions must be developed for Arabic-speaking migrants to improve access to available health services, facilitate timely diagnosis of diabetes and ultimately to improve glycaemic control. PMID:26576809

Improving Access to Data While Protecting Confidentiality: Prospects for the Future.

ERIC Educational Resources Information Center

Duncan, George T.; Pearson, Robert W.

Providing researchers, especially those in the social sciences, with access to publicly collected microdata furthers research while advancing public policy goals in a democratic society. However, while technological improvements have eased remote access to these databases and enabled computer using researchers to perform sophisticated statistical…

5 CFR 1320.14 - Public access.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Public access. 1320.14 Section 1320.14 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET OMB DIRECTIVES CONTROLLING PAPERWORK BURDENS ON THE PUBLIC § 1320.14 Public access. (a) In order to enable the public to participate in and provide comments...

Enabling Discoveries in Earth Sciences Through the Geosciences Network (GEON)

NASA Astrophysics Data System (ADS)

Seber, D.; Baru, C.; Memon, A.; Lin, K.; Youn, C.

2005-12-01

Taking advantage of the state-of-the-art information technology resources GEON researchers are building a cyberinfrastructure designed to enable data sharing, semantic data integration, high-end computations and 4D visualization in easy-to-use web-based environments. The GEON Network currently allows users to search and register Earth science resources such as data sets (GIS layers, GMT files, geoTIFF images, ASCII files, relational databases etc), software applications or ontologies. Portal based access mechanisms enable developers to built dynamic user interfaces to conduct advanced processing and modeling efforts across distributed computers and supercomputers. Researchers and educators can access the networked resources through the GEON portal and its portlets that were developed to conduct better and more comprehensive science and educational studies. For example, the SYNSEIS portlet in GEON enables users to access in near-real time seismic waveforms from the IRIS Data Management Center, easily build a 3D geologic model within the area of the seismic station(s) and the epicenter and perform a 3D synthetic seismogram analysis to understand the lithospheric structure and earthquake source parameters for any given earthquake in the US. Similarly, GEON's workbench area enables users to create their own work environment and copy, visualize and analyze any data sets within the network, and create subsets of the data sets for their own purposes. Since all these resources are built as part of a Service-oriented Architecture (SOA), they are also used in other development platforms. One such platform is Kepler Workflow system which can access web service based resources and provides users with graphical programming interfaces to build a model to conduct computations and/or visualization efforts using the networked resources. Developments in the area of semantic integration of the networked datasets continue to advance and prototype studies can be accessed via the GEON portal at www.geongrid.org

Automating variable rate irrigation management prescriptions for center pivots from field data maps

USDA-ARS?s Scientific Manuscript database

Variable rate irrigation (VRI) enables center pivot systems to match irrigation application to non-uniform field needs. This technology has potential to improve application and water-use efficiency while reducing environmental impacts from excess runoff and poor water quality. Proper management of V...

76 FR 69307 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-08

...)) that includes performance data, unless the sales literature also includes the appropriate uniformly... sales literature is designed to prevent misleading performance claims by funds and to enable investors... 34b-1 under the Investment Company Act (17 CFR 270.34b-1) governs sales material that accompanies or...

36 CFR 1207.42 - Retention and access requirements for records.

Code of Federal Regulations, 2010 CFR

2010-07-01

... RECORDS ADMINISTRATION GENERAL RULES UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND COOPERATIVE...) If any litigation, claim, negotiation, audit or other action involving the records has been started... to the awarding agency its single or last expenditure report for that period. However, if grant...

49 CFR 1542.211 - Identification systems.

Code of Federal Regulations, 2010 CFR

2010-10-01

... secured area or SIDA continuously displays the identification medium issued to that individual on the... individual who has authorized unescorted access to secured areas and SIDA's to ascertain the authority of any... approved identification media. The procedure must— (1) Apply uniformly in secured areas, SIDAs, and...

7 CFR 3015.21 - Retention period.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Retention period. 3015.21 Section 3015.21 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF AGRICULTURE UNIFORM FEDERAL ASSISTANCE REGULATIONS Record Retention and Access Requirements § 3015.21...

40 CFR 31.42 - Retention and access requirements for records.

Code of Federal Regulations, 2010 CFR

2010-07-01

... records. 31.42 Section 31.42 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND COOPERATIVE AGREEMENTS TO STATE AND LOCAL GOVERNMENTS Post-Award Requirements Reports, Records, Retention, and Enforcement § 31.42 Retention...

49 CFR 1542.211 - Identification systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... secured area or SIDA continuously displays the identification medium issued to that individual on the... individual who has authorized unescorted access to secured areas and SIDA's to ascertain the authority of any... approved identification media. The procedure must— (1) Apply uniformly in secured areas, SIDAs, and...

49 CFR 1542.211 - Identification systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

... secured area or SIDA continuously displays the identification medium issued to that individual on the... individual who has authorized unescorted access to secured areas and SIDA's to ascertain the authority of any... approved identification media. The procedure must— (1) Apply uniformly in secured areas, SIDAs, and...

49 CFR 1542.211 - Identification systems.

Code of Federal Regulations, 2011 CFR

2011-10-01

... secured area or SIDA continuously displays the identification medium issued to that individual on the... individual who has authorized unescorted access to secured areas and SIDA's to ascertain the authority of any... approved identification media. The procedure must— (1) Apply uniformly in secured areas, SIDAs, and...

49 CFR 1542.211 - Identification systems.

Code of Federal Regulations, 2012 CFR

2012-10-01

... secured area or SIDA continuously displays the identification medium issued to that individual on the... individual who has authorized unescorted access to secured areas and SIDA's to ascertain the authority of any... approved identification media. The procedure must— (1) Apply uniformly in secured areas, SIDAs, and...

44 CFR 13.42 - Retention and access requirements for records.

Code of Federal Regulations, 2014 CFR

2014-10-01

... AGENCY, DEPARTMENT OF HOMELAND SECURITY GENERAL UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND... to all financial and programmatic records, supporting documents, statistical records, and other... computations of the rate at which a particular group of costs is chargeable (such as computer usage chargeback...

44 CFR 13.42 - Retention and access requirements for records.

Code of Federal Regulations, 2011 CFR

2011-10-01

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Taking It Online: A Bootstraps Approach.

ERIC Educational Resources Information Center

Sabine, Ginger; Gilley, Daryl

This paper describes the process of creating an online course at the Northwestern Technical Institute (Georgia) using locally produced lessons, supplemental text, threaded discussion groups, online examinations, and student access to a transparent third party URL (Uniform Resource Locator). The course, developed for the Microsoft Office User…

Uniform field loop-gap resonator and rectangular TEU02 for aqueous sample EPR at 94 GHz

NASA Astrophysics Data System (ADS)

Sidabras, Jason W.; Sarna, Tadeusz; Mett, Richard R.; Hyde, James S.

2017-09-01

In this work we present the design and implementation of two uniform-field resonators: a seven-loop-six-gap loop-gap resonator (LGR) and a rectangular TEU02 cavity resonator. Each resonator has uniform-field-producing end-sections. These resonators have been designed for electron paramagnetic resonance (EPR) of aqueous samples at 94 GHz. The LGR geometry employs low-loss Rexolite end-sections to improve the field homogeneity over a 3 mm sample region-of-interest from near-cosine distribution to 90% uniform. The LGR was designed to accommodate large degassable Polytetrafluorethylen (PTFE) tubes (0.81 mm O.D.; 0.25 mm I.D.) for aqueous samples. Additionally, field modulation slots are designed for uniform 100 kHz field modulation incident at the sample. Experiments using a point sample of lithium phthalocyanine (LiPC) were performed to measure both the uniformity of the microwave magnetic field and 100 kHz field modulation, and confirm simulations. The rectangular TEU02 cavity resonator employs over-sized end-sections with sample shielding to provide an 87% uniform field for a 0.1 × 2 × 6 mm3 sample geometry. An evanescent slotted window was designed for light access to irradiate 90% of the sample volume. A novel dual-slot iris was used to minimize microwave magnetic field perturbations and maintain cross-sectional uniformity. Practical EPR experiments using the application of light irradiated rose bengal (4,5,6,7-tetrachloro-2‧,4‧,5‧,7‧-tetraiodofluorescein) were performed in the TEU02 cavity. The implementation of these geometries providing a practical designs for uniform field resonators that continue resonator advancements towards quantitative EPR spectroscopy.

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues.

PubMed

Corces, M Ryan; Trevino, Alexandro E; Hamilton, Emily G; Greenside, Peyton G; Sinnott-Armstrong, Nicholas A; Vesuna, Sam; Satpathy, Ansuman T; Rubin, Adam J; Montine, Kathleen S; Wu, Beijing; Kathiria, Arwa; Cho, Seung Woo; Mumbach, Maxwell R; Carter, Ava C; Kasowski, Maya; Orloff, Lisa A; Risca, Viviana I; Kundaje, Anshul; Khavari, Paul A; Montine, Thomas J; Greenleaf, William J; Chang, Howard Y

2017-10-01

We present Omni-ATAC, an improved ATAC-seq protocol for chromatin accessibility profiling that works across multiple applications with substantial improvement of signal-to-background ratio and information content. The Omni-ATAC protocol generates chromatin accessibility profiles from archival frozen tissue samples and 50-μm sections, revealing the activities of disease-associated DNA elements in distinct human brain structures. The Omni-ATAC protocol enables the interrogation of personal regulomes in tissue context and translational studies.

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Combining data from multiple sources using the CUAHSI Hydrologic Information System

NASA Astrophysics Data System (ADS)

Tarboton, D. G.; Ames, D. P.; Horsburgh, J. S.; Goodall, J. L.

2012-12-01

The Consortium of Universities for the Advancement of Hydrologic Science, Inc. (CUAHSI) has developed a Hydrologic Information System (HIS) to provide better access to data by enabling the publication, cataloging, discovery, retrieval, and analysis of hydrologic data using web services. The CUAHSI HIS is an Internet based system comprised of hydrologic databases and servers connected through web services as well as software for data publication, discovery and access. The HIS metadata catalog lists close to 100 web services registered to provide data through this system, ranging from large federal agency data sets to experimental watersheds managed by University investigators. The system's flexibility in storing and enabling public access to similarly formatted data and metadata has created a community data resource from governmental and academic data that might otherwise remain private or analyzed only in isolation. Comprehensive understanding of hydrology requires integration of this information from multiple sources. HydroDesktop is the client application developed as part of HIS to support data discovery and access through this system. HydroDesktop is founded on an open source GIS client and has a plug-in architecture that has enabled the integration of modeling and analysis capability with the functionality for data discovery and access. Model integration is possible through a plug-in built on the OpenMI standard and data visualization and analysis is supported by an R plug-in. This presentation will demonstrate HydroDesktop, showing how it provides an analysis environment within which data from multiple sources can be discovered, accessed and integrated.

"OnTrack" to University: Understanding Mechanisms of Student Retention in an Australian Pre-University Enabling Program

ERIC Educational Resources Information Center

Lisciandro, Joanne G.; Gibbs, Gael

2016-01-01

University-based enabling programs have become an important pathway to university for non-traditional students. There is increasing interest in understanding the mechanisms that facilitate retention and success of enabling pathway students, with the aim of developing effective strategies for maximising opportunities for university access and…

Nuclear Rocket Ceramic Metal Fuel Fabrication Using Tungsten Powder Coating and Spark Plasma Sintering

NASA Technical Reports Server (NTRS)

Barnes, M. W.; Tucker, D. S.; Hone, L.; Cook, S.

2017-01-01

Nuclear thermal propulsion is an enabling technology for crewed Mars missions. An investigation was conducted to evaluate spark plasma sintering (SPS) as a method to produce tungsten-depleted uranium dioxide (W-dUO2) fuel material when employing fuel particles that were tungsten powder coated. Ceramic metal fuel wafers were produced from a blend of W-60vol% dUO2 powder that was sintered via SPS. The maximum sintering temperatures were varied from 1,600 to 1,850 C while applying a 50-MPa axial load. Wafers exhibited high density (>95% of theoretical) and a uniform microstructure (fuel particles uniformly dispersed throughout tungsten matrix).

Large-area synthesis of high-quality and uniform monolayer WS2 on reusable Au foils

PubMed Central

Gao, Yang; Liu, Zhibo; Sun, Dong-Ming; Huang, Le; Ma, Lai-Peng; Yin, Li-Chang; Ma, Teng; Zhang, Zhiyong; Ma, Xiu-Liang; Peng, Lian-Mao; Cheng, Hui-Ming; Ren, Wencai

2015-01-01

Large-area monolayer WS2 is a desirable material for applications in next-generation electronics and optoelectronics. However, the chemical vapour deposition (CVD) with rigid and inert substrates for large-area sample growth suffers from a non-uniform number of layers, small domain size and many defects, and is not compatible with the fabrication process of flexible devices. Here we report the self-limited catalytic surface growth of uniform monolayer WS2 single crystals of millimetre size and large-area films by ambient-pressure CVD on Au. The weak interaction between the WS2 and Au enables the intact transfer of the monolayers to arbitrary substrates using the electrochemical bubbling method without sacrificing Au. The WS2 shows high crystal quality and optical and electrical properties comparable or superior to mechanically exfoliated samples. We also demonstrate the roll-to-roll/bubbling production of large-area flexible films of uniform monolayer, double-layer WS2 and WS2/graphene heterostructures, and batch fabrication of large-area flexible monolayer WS2 film transistor arrays. PMID:26450174

CHRR: coordinate hit-and-run with rounding for uniform sampling of constraint-based models.

PubMed

Haraldsdóttir, Hulda S; Cousins, Ben; Thiele, Ines; Fleming, Ronan M T; Vempala, Santosh

2017-06-01

In constraint-based metabolic modelling, physical and biochemical constraints define a polyhedral convex set of feasible flux vectors. Uniform sampling of this set provides an unbiased characterization of the metabolic capabilities of a biochemical network. However, reliable uniform sampling of genome-scale biochemical networks is challenging due to their high dimensionality and inherent anisotropy. Here, we present an implementation of a new sampling algorithm, coordinate hit-and-run with rounding (CHRR). This algorithm is based on the provably efficient hit-and-run random walk and crucially uses a preprocessing step to round the anisotropic flux set. CHRR provably converges to a uniform stationary sampling distribution. We apply it to metabolic networks of increasing dimensionality. We show that it converges several times faster than a popular artificial centering hit-and-run algorithm, enabling reliable and tractable sampling of genome-scale biochemical networks. https://github.com/opencobra/cobratoolbox . ronan.mt.fleming@gmail.com or vempala@cc.gatech.edu. Supplementary data are available at Bioinformatics online. © The Author 2017. Published by Oxford University Press.

Novel nanometer-level uniform amorphous carbon coating for boron powders by direct pyrolysis of coronene without solvent.

PubMed

Ye, ShuJun; Song, MingHui; Kumakura, Hiroaki

2015-01-30

A 3 nm coronene coating and a 4 nm amorphous carbon coating with a uniform shell-core encapsulation structure for nanosized boron (B) powders are formed by a simple process in which coronene is directly mixed with boron particles without a solvent and heated at 520 °C for 1 h or at 630 °C for 3 h in a vacuum-sealed silica tube. Coronene has a melting point lower than its decomposition temperature, which enables liquid coronene to cover B particles by liquid diffusion and penetration without the need for a solvent. The diffusion and penetration of coronene can extend to the boundaries of particles and to inside the agglomerated nanoparticles to form a complete shell-core encapsulated structure. As the temperature is increased, thermal decomposition of coronene on the B particles results in the formation of a uniform amorphous carbon coating layer. This novel and simple nanometer-level uniform amorphous carbon coating method can possibly be applied to many other powders; thus, it has potential applications in many fields at low cost.

Phase retrieval with the transport-of-intensity equation in an arbitrarily-shaped aperture by iterative discrete cosine transforms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Lei; Zuo, Chao; Idir, Mourad

A novel transport-of-intensity equation (TIE) based phase retrieval method is proposed with putting an arbitrarily-shaped aperture into the optical wavefield. In this arbitrarily-shaped aperture, the TIE can be solved under non-uniform illuminations and even non-homogeneous boundary conditions by iterative discrete cosine transforms with a phase compensation mechanism. Simulation with arbitrary phase, arbitrary aperture shape, and non-uniform intensity distribution verifies the effective compensation and high accuracy of the proposed method. Experiment is also carried out to check the feasibility of the proposed method in real measurement. Comparing to the existing methods, the proposed method is applicable for any types of phasemore » distribution under non-uniform illumination and non-homogeneous boundary conditions within an arbitrarily-shaped aperture, which enables the technique of TIE with hard aperture become a more flexible phase retrieval tool in practical measurements.« less

Phase retrieval with the transport-of-intensity equation in an arbitrarily-shaped aperture by iterative discrete cosine transforms

DOE PAGES

Huang, Lei; Zuo, Chao; Idir, Mourad; ...

2015-04-21

A novel transport-of-intensity equation (TIE) based phase retrieval method is proposed with putting an arbitrarily-shaped aperture into the optical wavefield. In this arbitrarily-shaped aperture, the TIE can be solved under non-uniform illuminations and even non-homogeneous boundary conditions by iterative discrete cosine transforms with a phase compensation mechanism. Simulation with arbitrary phase, arbitrary aperture shape, and non-uniform intensity distribution verifies the effective compensation and high accuracy of the proposed method. Experiment is also carried out to check the feasibility of the proposed method in real measurement. Comparing to the existing methods, the proposed method is applicable for any types of phasemore » distribution under non-uniform illumination and non-homogeneous boundary conditions within an arbitrarily-shaped aperture, which enables the technique of TIE with hard aperture become a more flexible phase retrieval tool in practical measurements.« less

Uniform, dense arrays of vertically aligned, large-diameter single-walled carbon nanotubes.

PubMed

Han, Zhao Jun; Ostrikov, Kostya

2012-04-04

Precisely controlled reactive chemical vapor synthesis of highly uniform, dense arrays of vertically aligned single-walled carbon nanotubes (SWCNTs) using tailored trilayered Fe/Al(2)O(3)/SiO(2) catalyst is demonstrated. More than 90% population of thick nanotubes (>3 nm in diameter) can be produced by tailoring the thickness and microstructure of the secondary catalyst supporting SiO(2) layer, which is commonly overlooked. The proposed model based on the atomic force microanalysis suggests that this tailoring leads to uniform and dense arrays of relatively large Fe catalyst nanoparticles on which the thick SWCNTs nucleate, while small nanotubes and amorphous carbon are effectively etched away. Our results resolve a persistent issue of selective (while avoiding multiwalled nanotubes and other carbon nanostructures) synthesis of thick vertically aligned SWCNTs whose easily switchable thickness-dependent electronic properties enable advanced applications in nanoelectronic, energy, drug delivery, and membrane technologies.

Patterned growth of carbon nanotubes over vertically aligned silicon nanowire bundles for achieving uniform field emission.

PubMed

Hung, Yung-Jr; Huang, Yung-Jui; Chang, Hsuan-Chen; Lee, Kuei-Yi; Lee, San-Liang

2014-01-01

A fabrication strategy is proposed to enable precise coverage of as-grown carbon nanotube (CNT) mats atop vertically aligned silicon nanowire (VA-SiNW) bundles in order to realize a uniform bundle array of CNT-SiNW heterojunctions over a large sample area. No obvious electrical degradation of as-fabricated SiNWs is observed according to the measured current-voltage characteristic of a two-terminal single-nanowire device. Bundle arrangement of CNT-SiNW heterojunctions is optimized to relax the electrostatic screening effect and to maximize the field enhancement factor. As a result, superior field emission performance and relatively stable emission current over 12 h is obtained. A bright and uniform fluorescent radiation is observed from CNT-SiNW-based field emitters regardless of its bundle periodicity, verifying the existence of high-density and efficient field emitters on the proposed CNT-SiNW bundle arrays.

DataHub: Science data management in support of interactive exploratory analysis

NASA Technical Reports Server (NTRS)

Handley, Thomas H., Jr.; Rubin, Mark R.

1993-01-01

The DataHub addresses four areas of significant needs: scientific visualization and analysis; science data management; interactions in a distributed, heterogeneous environment; and knowledge-based assistance for these functions. The fundamental innovation embedded within the DataHub is the integration of three technologies, viz. knowledge-based expert systems, science visualization, and science data management. This integration is based on a concept called the DataHub. With the DataHub concept, science investigators are able to apply a more complete solution to all nodes of a distributed system. Both computational nodes and interactives nodes are able to effectively and efficiently use the data services (access, retrieval, update, etc), in a distributed, interdisciplinary information system in a uniform and standard way. This allows the science investigators to concentrate on their scientific endeavors, rather than to involve themselves in the intricate technical details of the systems and tools required to accomplish their work. Thus, science investigators need not be programmers. The emphasis on the definition and prototyping of system elements with sufficient detail to enable data analysis and interpretation leading to information. The DataHub includes all the required end-to-end components and interfaces to demonstrate the complete concept.

DataHub - Science data management in support of interactive exploratory analysis

NASA Technical Reports Server (NTRS)

Handley, Thomas H., Jr.; Rubin, Mark R.

1993-01-01

DataHub addresses four areas of significant need: scientific visualization and analysis; science data management; interactions in a distributed, heterogeneous environment; and knowledge-based assistance for these functions. The fundamental innovation embedded within the DataHub is the integration of three technologies, viz. knowledge-based expert systems, science visualization, and science data management. This integration is based on a concept called the DataHub. With the DataHub concept, science investigators are able to apply a more complete solution to all nodes of a distributed system. Both computational nodes and interactive nodes are able to effectively and efficiently use the data services (access, retrieval, update, etc.) in a distributed, interdisciplinary information system in a uniform and standard way. This allows the science investigators to concentrate on their scientific endeavors, rather than to involve themselves in the intricate technical details of the systems and tools required to accomplish their work. Thus, science investigators need not be programmers. The emphasis is on the definition and prototyping of system elements with sufficient detail to enable data analysis and interpretation leading to information. The DataHub includes all the required end-to-end components and interfaces to demonstrate the complete concept.

A lightweight Web of Things Open Platform to facilitate context data management and personalized healthcare services creation.

PubMed

Corredor, Iván; Metola, Eduardo; Bernardos, Ana M; Tarrío, Paula; Casar, José R

2014-04-29

In the last few years, many health monitoring systems have been designed to fullfil the needs of a large range of scenarios. Although many of those systems provide good ad hoc solutions, most of them lack of mechanisms that allow them to be easily reused. This paper is focused on describing an open platform, the micro Web of Things Open Platform (µWoTOP), which has been conceived to improve the connectivity and reusability of context data to deliver different kinds of health, wellness and ambient home care services. µWoTOP is based on a resource-oriented architecture which may be embedded in mobile and resource constrained devices enabling access to biometric, ambient or activity sensors and actuator resources through uniform interfaces defined according to a RESTful fashion. Additionally, µWoTOP manages two communication modes which allow delivering user context information according to different methods, depending on the requirements of the consumer application. It also generates alert messages based on standards related to health care and risk management, such as the Common Alerting Protocol, in order to make its outputs compatible with existing systems.

Machine Aided Indexing and the NASA Thesaurus

NASA Technical Reports Server (NTRS)

vonOfenheim, Bill

2007-01-01

Machine Aided Indexing (MAI) is a Web-based application program for aiding the indexing of literature in the NASA Scientific and Technical Information (STI) Database. MAI was designed to be a convenient, fully interactive tool for determining the subject matter of documents and identifying keywords. The heart of MAI is a natural-language processor that accepts, as input, any user-supplied text, including abstracts, full documents, and Web pages. Within seconds, the text is analyzed and a ranked list of terms is generated. The 17,800 terms of the NASA Thesaurus serve as the foundation of the knowledge base used by MAI. The NASA Thesaurus defines a standard vocabulary, the use of which enables MAI to assist in ensuring that STI documents are uniformly and consistently accessible. Of particular interest to traditional users of the NASA Thesaurus, MAI incorporates a fully searchable thesaurus display module that affords word-search and hierarchy- navigation capabilities that make it much easier and less time-consuming to look up terms and browse, relative to lookup and browsing in older print and Portable Document Format (PDF) digital versions of the Thesaurus. In addition, because MAI is centrally hosted, the Thesaurus data are always current.

Design and fabrication of an E-shaped wearable textile antenna on PVB-coated hydrophobic polyester fabric

NASA Astrophysics Data System (ADS)

Babu Roshni, Satheesh; Jayakrishnan, M. P.; Mohanan, P.; Peethambharan Surendran, Kuzhichalil

2017-10-01

In this paper, we investigated the simulation and fabrication of an E-shaped microstrip patch antenna realized on multilayered polyester fabric suitable for WiMAX (Worldwide Interoperability for Microwave Access) applications. The main challenges while designing a textile antenna were to provide adequate thickness, surface uniformity and water wettability to the textile substrate. Here, three layers of polyester fabric were stacked together in order to obtain sufficient thickness, and were subsequently dip coated with polyvinyl butyral (PVB) solution. The PVB-coated polyester fabric showed a hydrophobic nature with a contact angle of 91°. The RMS roughness of the uncoated and PVB-coated polyester fabric was about 341 nm and 15 nm respectively. The promising properties, such as their flexibility, light weight and cost effectiveness, enable effortless integration of the proposed antenna into clothes like polyester jackets. Simulated and measured results in terms of return loss as well as gain were showcased to confirm the usefulness of the fabricated prototype. The fabricated antenna successfully operates at 3.37 GHz with a return loss of 21 dB and a maximum measured gain of 3.6 dB.

A Lightweight Web of Things Open Platform to Facilitate Context Data Management and Personalized Healthcare Services Creation

PubMed Central

Corredor, Iván; Metola, Eduardo; Bernardos, Ana M.; Tarrío, Paula; Casar, José R.

2014-01-01

In the last few years, many health monitoring systems have been designed to fullfil the needs of a large range of scenarios. Although many of those systems provide good ad hoc solutions, most of them lack of mechanisms that allow them to be easily reused. This paper is focused on describing an open platform, the micro Web of Things Open Platform (µWoTOP), which has been conceived to improve the connectivity and reusability of context data to deliver different kinds of health, wellness and ambient home care services. µWoTOP is based on a resource-oriented architecture which may be embedded in mobile and resource constrained devices enabling access to biometric, ambient or activity sensors and actuator resources through uniform interfaces defined according to a RESTful fashion. Additionally, µWoTOP manages two communication modes which allow delivering user context information according to different methods, depending on the requirements of the consumer application. It also generates alert messages based on standards related to health care and risk management, such as the Common Alerting Protocol, in order to make its outputs compatible with existing systems. PMID:24785542

Resistive switching characteristics of manganese oxide thin film and nanoparticle assembly hybrid devices

NASA Astrophysics Data System (ADS)

Abbas, Haider; Park, Mi Ra; Abbas, Yawar; Hu, Quanli; Kang, Tae Su; Yoon, Tae-Sik; Kang, Chi Jung

2018-06-01

Improved resistive switching characteristics are demonstrated in a hybrid device with Pt/Ti/MnO (thin film)/MnO (nanoparticle)/Pt structure. The hybrid devices of MnO thin film and nanoparticle assembly were fabricated. MnO nanoparticles with an average diameter of ∼30 nm were chemically synthesized and assembled as a monolayer on a Pt bottom electrode. A MnO thin film of ∼40 nm thickness was deposited on the nanoparticle assembly to form the hybrid structure. Resistive switching could be induced by the formation and rupture of conducting filaments in the hybrid oxide layers. The hybrid device exhibited very stable unipolar switching with good endurance and retention characteristics. It showed a larger and stable memory window with a uniform distribution of SET and RESET voltages. Moreover, the conduction mechanisms of ohmic conduction, space-charge-limited conduction, Schottky emission, and Poole–Frenkel emission have been investigated as possible conduction mechanisms for the switching of the devices. Using MnO nanoparticles in the thin film and nanoparticle heterostructures enabled the appropriate control of resistive random access memory (RRAM) devices and markedly improved their memory characteristics.

A collection of micrographs: where science and art meet

PubMed Central

Uskoković, Vuk

2013-01-01

Micrographs obtained using different instrumental techniques are presented with the purpose of demonstrating their artistic qualities. The quality of uniformity currently dominates the aesthetic assessment in scientific practice and is discussed in relation to the classical appreciation of the interplay between symmetry and asymmetry in arts. It is argued that scientific and artistic qualities have converged and inspired each other throughout millennia. With scientific discoveries and inventions enriching the world of communication, broadening the space for artistic creativity and making artistic products more accessible than ever, science inevitably influences artistic creativity. On the other hand, the importance of aesthetic principles in guiding scientific conduct has been appreciated by some of the most creative scientific minds. Science and arts can be thus considered as parallel rails of a single railroad track. Only when precisely coordinated is the passing of the train of human knowledge enabled. The presented micrographs, occupying the central part of this discourse, are displayed with the purpose of showing the rich aesthetic character of even the most ordinary scientific images. The inherent aesthetic nature of scientific imagery and the artistic nature of scientific conduct have thus been offered as the conclusion. PMID:24465169

Computational adaptive optics for broadband optical interferometric tomography of biological tissue.

PubMed

Adie, Steven G; Graf, Benedikt W; Ahmad, Adeel; Carney, P Scott; Boppart, Stephen A

2012-05-08

Aberrations in optical microscopy reduce image resolution and contrast, and can limit imaging depth when focusing into biological samples. Static correction of aberrations may be achieved through appropriate lens design, but this approach does not offer the flexibility of simultaneously correcting aberrations for all imaging depths, nor the adaptability to correct for sample-specific aberrations for high-quality tomographic optical imaging. Incorporation of adaptive optics (AO) methods have demonstrated considerable improvement in optical image contrast and resolution in noninterferometric microscopy techniques, as well as in optical coherence tomography. Here we present a method to correct aberrations in a tomogram rather than the beam of a broadband optical interferometry system. Based on Fourier optics principles, we correct aberrations of a virtual pupil using Zernike polynomials. When used in conjunction with the computed imaging method interferometric synthetic aperture microscopy, this computational AO enables object reconstruction (within the single scattering limit) with ideal focal-plane resolution at all depths. Tomographic reconstructions of tissue phantoms containing subresolution titanium-dioxide particles and of ex vivo rat lung tissue demonstrate aberration correction in datasets acquired with a highly astigmatic illumination beam. These results also demonstrate that imaging with an aberrated astigmatic beam provides the advantage of a more uniform depth-dependent signal compared to imaging with a standard gaussian beam. With further work, computational AO could enable the replacement of complicated and expensive optical hardware components with algorithms implemented on a standard desktop computer, making high-resolution 3D interferometric tomography accessible to a wider group of users and nonspecialists.

Middleware for Plug and Play Integration of Heterogeneous Sensor Resources into the Sensor Web

PubMed Central

Toma, Daniel M.; Jirka, Simon; Del Río, Joaquín

2017-01-01

The study of global phenomena requires the combination of a considerable amount of data coming from different sources, acquired by different observation platforms and managed by institutions working in different scientific fields. Merging this data to provide extensive and complete data sets to monitor the long-term, global changes of our oceans is a major challenge. The data acquisition and data archival procedures usually vary significantly depending on the acquisition platform. This lack of standardization ultimately leads to information silos, preventing the data to be effectively shared across different scientific communities. In the past years, important steps have been taken in order to improve both standardization and interoperability, such as the Open Geospatial Consortium’s Sensor Web Enablement (SWE) framework. Within this framework, standardized models and interfaces to archive, access and visualize the data from heterogeneous sensor resources have been proposed. However, due to the wide variety of software and hardware architectures presented by marine sensors and marine observation platforms, there is still a lack of uniform procedures to integrate sensors into existing SWE-based data infrastructures. In this work, a framework aimed to enable sensor plug and play integration into existing SWE-based data infrastructures is presented. First, an analysis of the operations required to automatically identify, configure and operate a sensor are analysed. Then, the metadata required for these operations is structured in a standard way. Afterwards, a modular, plug and play, SWE-based acquisition chain is proposed. Finally different use cases for this framework are presented. PMID:29244732

Enhancing the Capacity of Community Organizations to Evaluate HIV/AIDS Information Outreach: A Pilot Experiment in Expert Consultation

PubMed Central

Dancy-Scott, Nicole; Williams-Livingston, Arletha; Plumer, Andrew; Dutcher, Gale A.; Siegel, Elliot R.

2017-01-01

The National Library of Medicine’s AIDS Community Information Outreach Program (ACIOP) supports and enables access to health information on the Internet by community-based organizations. A technical assistance (TA) model was developed to enhance the capacity of ACIOP awardees to plan, evaluate, and report the results of their funded projects. This consisted of individual Consultation offered by an experienced evaluator to advise on the suitability of proposed project plans and objectives, improve measurement analytics, assist in problem resolution and outcomes reporting, and identify other improvement possibilities. Group webinars and a moderated blog for the exchange of project-specific information were also offered. Structured data collections in the form of reports, online surveys, and key informant telephone interviews provided qualitative feedback on project progress, satisfaction with the TA, and the perceived impact of the interventions on evaluation capacity building. The Model was implemented in the 2013 funding cycle with seven organizations, and the level of reported satisfaction was uniformly high. One-on-one TA was requested by four awardee organizations, and was determined to have made a meaningful difference with three. Participation in the webinars was mandatory and high overall; and was deemed to be a useful means for delivering evaluation information. In subsequent funding cycles, submission of a Logic Model will be required of awardees as a new model intervention in the expectation that it will produce stronger proposals, and enable the evaluation consultant to identify earlier intervention opportunities leading to project improvements and evaluation capacity enhancements. PMID:28405054

A crisis in chronic pain care: an ethical analysis. Part three: Toward an integrative, multi-disciplinary pain medicine built around the needs of the patient.

PubMed

Giordano, James; Schatman, Michael E

2008-01-01

A number of variables have contributed to the current crisis in chronic pain care and are affected by, and affect, the philosophies and politics that influence the socio-economic climate of the American healthcare system. Thus, we posit that managing the crisis in chronic pain care in the United States is contingent upon the development of a multi-focal healthcare paradigm that more thoroughly enables and fortifies research, its translation (in education and practice), and the implementation of, and support for, both the curative and healing approaches in medicine in general, and pain care specifically. These steps necessitate re-examination, if not revision of the health care system and its economics. The ethical imperative to consider and prudently employ cutting-edge diagnostic and therapeutic technologies in pain medicine is obligatory. However, "supply side prudence" is of little value if "demand side accessibility" is lacking. Revisions to health insurance plans advocated by the in-coming administration seek to create uniformity in basic health care services based upon re-assessment of the clinical effectiveness (versus merely cost) of treatments, including those that are "high tech." These plans attempt to allow every patient a more complete ability to deliberatively work with physicians to access those services and resources that maximize health functioning and goals. But even given these revisions, authentic pain care must take into account the interactive contexts of the painient individual. The biopsychosocial model of chronic pain management may have significant practical and ethical worth in this regard. A system of pain treatment operating from a biopsychosocial perspective necessitates integrative multi-disciplinarity. We propose a tiered, multi-disciplinary paradigm based upon the differing needs of each specific patient. But establishing such a system does not guarantee access, and distribution of these services and resources requires economic support to ensure that capabilities are more broadly available (i.e., supplied), and afforded as needed and wanted (i.e., demanded). Toward this end, we posit the need to focus upon, and more fully integrate 1) education, 2) multi-disciplinary care (including re-vivification of MPCs), 3) policies that allow financial subsidies that afford patients the latitude to access and utilize such expanded resources appropriately to meet identified medical needs, and 4) medico-legal initiatives and statutes that protect and enable patients and physicians. The proposed changes comport with a number of ethical systems in that they support the basic deontic structure of the profession and allow for a richer, more finely grained articulation of clinical and ethical responsibilities within the scope of particular general, specialty, and sub-specialty practices.

Towards a single seismological service infrastructure in Europe

NASA Astrophysics Data System (ADS)

Spinuso, A.; Trani, L.; Frobert, L.; Van Eck, T.

2012-04-01

In the last five year services and data providers, within the seismological community in Europe, focused their efforts in migrating the way of opening their archives towards a Service Oriented Architecture (SOA). This process tries to follow pragmatically the technological trends and available solutions aiming at effectively improving all the data stewardship activities. These advancements are possible thanks to the cooperation and the follow-ups of several EC infrastructural projects that, by looking at general purpose techniques, combine their developments envisioning a multidisciplinary platform for the earth observation as the final common objective (EPOS, Earth Plate Observation System) One of the first results of this effort is the Earthquake Data Portal (http://www.seismicportal.eu), which provides a collection of tools to discover, visualize and access a variety of seismological data sets like seismic waveform, accelerometric data, earthquake catalogs and parameters. The Portal offers a cohesive distributed search environment, linking data search and access across multiple data providers through interactive web-services, map-based tools and diverse command-line clients. Our work continues under other EU FP7 projects. Here we will address initiatives in two of those projects. The NERA, (Network of European Research Infrastructures for Earthquake Risk Assessment and Mitigation) project will implement a Common Services Architecture based on OGC services APIs, in order to provide Resource-Oriented common interfaces across the data access and processing services. This will improve interoperability between tools and across projects, enabling the development of higher-level applications that can uniformly access the data and processing services of all participants. This effort will be conducted jointly with the VERCE project (Virtual Earthquake and Seismology Research Community for Europe). VERCE aims to enable seismologists to exploit the wealth of seismic data within a data-intensive computation framework, which will be tailored to the specific needs of the community. It will provide a new interoperable infrastructure, as the computational backbone laying behind the publicly available interfaces. VERCE will have to face the challenges of implementing a service oriented architecture providing an efficient layer between the Data and the Grid infrastructures, coupling HPC data analysis and HPC data modeling applications through the execution of workflows and data sharing mechanism. Online registries of interoperable worklflow components, storage of intermediate results and data provenance are those aspects that are currently under investigations to make the VERCE facilities usable from a large scale of users, data and service providers. For such purposes the adoption of a Digital Object Architecture, to create online catalogs referencing and describing semantically all these distributed resources, such as datasets, computational processes and derivative products, is seen as one of the viable solution to monitor and steer the usage of the infrastructure, increasing its efficiency and the cooperation among the community.

20 CFR 437.42 - Retention and access requirements for records.

Code of Federal Regulations, 2012 CFR

2012-04-01

.... 437.42 Section 437.42 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE..., statistical records, and other records of grantees or subgrantees that are: (i) Required to be maintained by... (such as computer usage chargeback rates or composite fringe benefit rates). (i) If submitted for...

20 CFR 437.42 - Retention and access requirements for records.

Code of Federal Regulations, 2014 CFR

2014-04-01

.... 437.42 Section 437.42 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE..., statistical records, and other records of grantees or subgrantees that are: (i) Required to be maintained by... (such as computer usage chargeback rates or composite fringe benefit rates). (i) If submitted for...

20 CFR 437.42 - Retention and access requirements for records.

Code of Federal Regulations, 2013 CFR

2013-04-01

.... 437.42 Section 437.42 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE..., statistical records, and other records of grantees or subgrantees that are: (i) Required to be maintained by... (such as computer usage chargeback rates or composite fringe benefit rates). (i) If submitted for...

Dr. Tulga Ersal at NSF Workshop Accessible Remote Testbeds ART'15

Science.gov Websites

;Enabling High-Fidelity Closed-Loop Integration of Remotely Accessible Testbeds" at the NSF Sponsored project (2010-2013) "Internet-Distributed Hardware-in-the-Loop Simulation". Sponsored by U.S

Virtual Computing Laboratories: A Case Study with Comparisons to Physical Computing Laboratories

ERIC Educational Resources Information Center

Burd, Stephen D.; Seazzu, Alessandro F.; Conway, Christopher

2009-01-01

Current technology enables schools to provide remote or virtual computing labs that can be implemented in multiple ways ranging from remote access to banks of dedicated workstations to sophisticated access to large-scale servers hosting virtualized workstations. This paper reports on the implementation of a specific lab using remote access to…

Achieving Access to the General Curriculum for Students with Mental Retardation.

ERIC Educational Resources Information Center

Wehmeyer, Michael L.; Lattin, Dana; Agran, Martin

2001-01-01

This article reviews requirements in the Individuals with Disabilities Education Act for providing access to the general education curriculum, examines the intent of the language, and proposes a decision-making model to enable Individualized Education Program teams to reach curriculum decisions that provide such access for students with mental…

Achievable Rate Estimation of IEEE 802.11ad Visual Big-Data Uplink Access in Cloud-Enabled Surveillance Applications.

PubMed

Kim, Joongheon; Kim, Jong-Kook

2016-01-01

This paper addresses the computation procedures for estimating the impact of interference in 60 GHz IEEE 802.11ad uplink access in order to construct visual big-data database from randomly deployed surveillance camera sensing devices. The acquired large-scale massive visual information from surveillance camera devices will be used for organizing big-data database, i.e., this estimation is essential for constructing centralized cloud-enabled surveillance database. This performance estimation study captures interference impacts on the target cloud access points from multiple interference components generated by the 60 GHz wireless transmissions from nearby surveillance camera devices to their associated cloud access points. With this uplink interference scenario, the interference impacts on the main wireless transmission from a target surveillance camera device to its associated target cloud access point with a number of settings are measured and estimated under the consideration of 60 GHz radiation characteristics and antenna radiation pattern models.

From individual innovation to global impact: the Global Cooperation on Assistive Technology (GATE) innovation snapshot as a method for sharing and scaling.

PubMed

Layton, Natasha; Murphy, Caitlin; Bell, Diane

2018-07-01

Assistive technology (AT) is an essential facilitator of independence and participation, both for people living with the effects of disability and/or non-communicable disease, as well as people aging with resultant functional decline. The World Health Organization (WHO) recognizes the substantial gap between the need for and provision of AT and is leading change through the Global Cooperation on Assistive Technology (GATE) initiative. Showcasing innovations gathered from 92 global researchers, innovators, users and educators of AT through the WHO GREAT Summit, this article provides an analysis of ideas and actions on a range of dimensions in order to provide a global overview of AT innovation. The accessible method used to capture and showcase this data is presented and critiqued, concluding that "innovation snapshots" are a rapid and concise strategy to capture and showcase AT innovation and to foster global collaboration. Implications for Rehabilitation Focal tools such as ePosters with uniform data requirements enable the rapid sharing of information. A diversity of innovative practices are occurring globally in the areas of AT Products, Policy, Provision, People and Personnel. The method offered for Innovation Snapshots had substantial uptake and is a feasible means to capture data across a range of stakeholders. Meeting accessibility criteria is an emerging competency in the AT community. Substantial areas of common interest exist across regions and globally in the AT community, demonstrating the effectiveness of information sharing platforms such as GATE and supporting the idea of regional forums and networks.

Ultra-fast fluence optimization for beam angle selection algorithms

NASA Astrophysics Data System (ADS)

Bangert, M.; Ziegenhein, P.; Oelfke, U.

2014-03-01

Beam angle selection (BAS) including fluence optimization (FO) is among the most extensive computational tasks in radiotherapy. Precomputed dose influence data (DID) of all considered beam orientations (up to 100 GB for complex cases) has to be handled in the main memory and repeated FOs are required for different beam ensembles. In this paper, the authors describe concepts accelerating FO for BAS algorithms using off-the-shelf multiprocessor workstations. The FO runtime is not dominated by the arithmetic load of the CPUs but by the transportation of DID from the RAM to the CPUs. On multiprocessor workstations, however, the speed of data transportation from the main memory to the CPUs is non-uniform across the RAM; every CPU has a dedicated memory location (node) with minimum access time. We apply a thread node binding strategy to ensure that CPUs only access DID from their preferred node. Ideal load balancing for arbitrary beam ensembles is guaranteed by distributing the DID of every candidate beam equally to all nodes. Furthermore we use a custom sorting scheme of the DID to minimize the overall data transportation. The framework is implemented on an AMD Opteron workstation. One FO iteration comprising dose, objective function, and gradient calculation takes between 0.010 s (9 beams, skull, 0.23 GB DID) and 0.070 s (9 beams, abdomen, 1.50 GB DID). Our overall FO time is < 1 s for small cases, larger cases take ~ 4 s. BAS runs including FOs for 1000 different beam ensembles take ~ 15-70 min, depending on the treatment site. This enables an efficient clinical evaluation of different BAS algorithms.

The clinical trial landscape in oncology and connectivity of somatic mutational profiles to targeted therapies.

PubMed

Patterson, Sara E; Liu, Rangjiao; Statz, Cara M; Durkin, Daniel; Lakshminarayana, Anuradha; Mockus, Susan M

2016-01-16

Precision medicine in oncology relies on rapid associations between patient-specific variations and targeted therapeutic efficacy. Due to the advancement of genomic analysis, a vast literature characterizing cancer-associated molecular aberrations and relative therapeutic relevance has been published. However, data are not uniformly reported or readily available, and accessing relevant information in a clinically acceptable time-frame is a daunting proposition, hampering connections between patients and appropriate therapeutic options. One important therapeutic avenue for oncology patients is through clinical trials. Accordingly, a global view into the availability of targeted clinical trials would provide insight into strengths and weaknesses and potentially enable research focus. However, data regarding the landscape of clinical trials in oncology is not readily available, and as a result, a comprehensive understanding of clinical trial availability is difficult. To support clinical decision-making, we have developed a data loader and mapper that connects sequence information from oncology patients to data stored in an in-house database, the JAX Clinical Knowledgebase (JAX-CKB), which can be queried readily to access comprehensive data for clinical reporting via customized reporting queries. JAX-CKB functions as a repository to house expertly curated clinically relevant data surrounding our 358-gene panel, the JAX Cancer Treatment Profile (JAX CTP), and supports annotation of functional significance of molecular variants. Through queries of data housed in JAX-CKB, we have analyzed the landscape of clinical trials relevant to our 358-gene targeted sequencing panel to evaluate strengths and weaknesses in current molecular targeting in oncology. Through this analysis, we have identified patient indications, molecular aberrations, and targeted therapy classes that have strong or weak representation in clinical trials. Here, we describe the development and disseminate system methods for associating patient genomic sequence data with clinically relevant information, facilitating interpretation and providing a mechanism for informing therapeutic decision-making. Additionally, through customized queries, we have the capability to rapidly analyze the landscape of targeted therapies in clinical trials, enabling a unique view into current therapeutic availability in oncology.

Spatial access disparities to primary health care in rural and remote Australia.

PubMed

McGrail, Matthew Richard; Humphreys, John Stirling

2015-11-04

Poor spatial access to health care remains a key issue for rural populations worldwide. Whilst geographic information systems (GIS) have enabled the development of more sophisticated access measures, they are yet to be adopted into health policy and workforce planning. This paper provides and tests a new national-level approach to measuring primary health care (PHC) access for rural Australia, suitable for use in macro-level health policy. The new index was constructed using a modified two-step floating catchment area method framework and the smallest available geographic unit. Primary health care spatial access was operationalised using three broad components: availability of PHC (general practitioner) services; proximity of populations to PHC services; and PHC needs of the population. Data used in its measurement were specifically chosen for accuracy, reliability and ongoing availability for small areas. The resultant index reveals spatial disparities of access to PHC across rural Australia. While generally more remote areas experienced poorer access than more populated rural areas, there were numerous exceptions to this generalisation, with some rural areas close to metropolitan areas having very poor access and some increasingly remote areas having relatively good access. This new index provides a geographically-sensitive measure of access, which is readily updateable and enables a fine granulation of access disparities. Such an index can underpin national rural health programmes and policies designed to improve rural workforce recruitment and retention, and, importantly, health service planning and resource allocation decisions designed to improve equity of PHC access.

Rapid learning of visual ensembles.

PubMed

Chetverikov, Andrey; Campana, Gianluca; Kristjánsson, Árni

2017-02-01

We recently demonstrated that observers are capable of encoding not only summary statistics, such as mean and variance of stimulus ensembles, but also the shape of the ensembles. Here, for the first time, we show the learning dynamics of this process, investigate the possible priors for the distribution shape, and demonstrate that observers are able to learn more complex distributions, such as bimodal ones. We used speeding and slowing of response times between trials (intertrial priming) in visual search for an oddly oriented line to assess internal models of distractor distributions. Experiment 1 demonstrates that two repetitions are sufficient for enabling learning of the shape of uniform distractor distributions. In Experiment 2, we compared Gaussian and uniform distractor distributions, finding that following only two repetitions Gaussian distributions are represented differently than uniform ones. Experiment 3 further showed that when distractor distributions are bimodal (with a 30° distance between two uniform intervals), observers initially treat them as uniform, and only with further repetitions do they begin to treat the distributions as bimodal. In sum, observers do not have strong initial priors for distribution shapes and quickly learn simple ones but have the ability to adjust their representations to more complex feature distributions as information accumulates with further repetitions of the same distractor distribution.

High School Students' Self-Reported Use of School Clinics and Nurses.

PubMed

Harper, Christopher R; Liddon, Nicole; Dunville, Richard; Habel, Melissa A

2016-10-01

Access to school health clinics and nurses has been linked with improved student achievement and health. Unfortunately, no studies have examined how many students report using school clinics or nurses and for which services. This study addressed this gap with data from a nationally representative sample of 15- to 25-year-olds. Respondents who reported being in high school were provided a list of services and asked whether they had gone to a school nurse or clinic for any of the listed services. Nearly 90% reported having access to a school clinic or nurse. Among students with access, 65.6% reported using at least one service. Non-White students and younger students were more likely to report having access to a clinic or nurse. These results show many students have access to clinics or nurses and are using these services, although not uniformly for all services. © The Author(s) 2016.

Coater/developer based techniques to improve high-resolution EUV patterning defectivity

NASA Astrophysics Data System (ADS)

Hontake, Koichi; Huli, Lior; Lemley, Corey; Hetzer, Dave; Liu, Eric; Ko, Akiteru; Kawakami, Shinichiro; Shimoaoki, Takeshi; Hashimoto, Yusaku; Tanaka, Koichiro; Petrillo, Karen; Meli, Luciana; De Silva, Anuja; Xu, Yongan; Felix, Nelson; Johnson, Richard; Murray, Cody; Hubbard, Alex

2017-10-01

Extreme ultraviolet lithography (EUVL) technology is one of the leading candidates under consideration for enabling the next generation of devices, for 7nm node and beyond. As the focus shifts to driving down the 'effective' k1 factor and enabling the full scaling entitlement of EUV patterning, new techniques and methods must be developed to reduce the overall defectivity, mitigate pattern collapse, and eliminate film-related defects. In addition, CD uniformity and LWR/LER must be improved in terms of patterning performance. Tokyo Electron Limited (TEL™) and IBM Corporation are continuously developing manufacturing quality processes for EUV. In this paper, we review the ongoing progress in coater/developer based processes (coating, developing, baking) that are required to enable EUV patterning.

Technology-Enabled and Universally Designed Assessment: Considering Access in Measuring the Achievement of Students with Disabilities--A Foundation for Research

ERIC Educational Resources Information Center

Almond, Patricia; Winter, Phoebe; Cameto, Renee; Russell, Michael; Sato, Edynn; Clarke-Midura, Jody; Torres, Chloe; Haertel, Geneva; Dolan, Robert; Beddow, Peter; Lazarus, Sheryl

2010-01-01

This paper represents one outcome from the "Invitational Research Symposium on Technology-Enabled and Universally Designed Assessments," which examined technology-enabled assessments (TEA) and universal design (UD) as they relate to students with disabilities (SWD). It was developed to stimulate research into TEAs designed to make tests…

Core or Periphery? The Positioning of Language and Literacies in Enabling Programs in Australia

ERIC Educational Resources Information Center

Baker, Sally; Irwin, Evonne

2016-01-01

Enabling education has a respected and established place in Australian higher education as an alternative pathway into university study. While the value of enabling education in providing access to higher education is undeniable, its provision across Australia is necessarily diverse, as individual programs respond to the needs of their local…

Desynchronization boost by non-uniform coordinated reset stimulation in ensembles of pulse-coupled neurons

PubMed Central

Lücken, Leonhard; Yanchuk, Serhiy; Popovych, Oleksandr V.; Tass, Peter A.

2013-01-01

Several brain diseases are characterized by abnormal neuronal synchronization. Desynchronization of abnormal neural synchrony is theoretically compelling because of the complex dynamical mechanisms involved. We here present a novel type of coordinated reset (CR) stimulation. CR means to deliver phase resetting stimuli at different neuronal sub-populations sequentially, i.e., at times equidistantly distributed in a stimulation cycle. This uniform timing pattern seems to be intuitive and actually applies to the neural network models used for the study of CR so far. CR resets the population to an unstable cluster state from where it passes through a desynchronized transient, eventually resynchronizing if left unperturbed. In contrast, we show that the optimal stimulation times are non-uniform. Using the model of weakly pulse-coupled neurons with phase response curves, we provide an approach that enables to determine optimal stimulation timing patterns that substantially maximize the desynchronized transient time following the application of CR stimulation. This approach includes an optimization search for clusters in a low-dimensional pulse coupled map. As a consequence, model-specific non-uniformly spaced cluster states cause considerably longer desynchronization transients. Intriguingly, such a desynchronization boost with non-uniform CR stimulation can already be achieved by only slight modifications of the uniform CR timing pattern. Our results suggest that the non-uniformness of the stimulation times can be a medically valuable parameter in the calibration procedure for CR stimulation, where the latter has successfully been used in clinical and pre-clinical studies for the treatment of Parkinson's disease and tinnitus. PMID:23750134

Information Power Grid Posters

NASA Technical Reports Server (NTRS)

Vaziri, Arsi

2003-01-01

This document is a summary of the accomplishments of the Information Power Grid (IPG). Grids are an emerging technology that provide seamless and uniform access to the geographically dispersed, computational, data storage, networking, instruments, and software resources needed for solving large-scale scientific and engineering problems. The goal of the NASA IPG is to use NASA's remotely located computing and data system resources to build distributed systems that can address problems that are too large or complex for a single site. The accomplishments outlined in this poster presentation are: access to distributed data, IPG heterogeneous computing, integration of large-scale computing node into distributed environment, remote access to high data rate instruments,and exploratory grid environment.

Accuracy of a Screening Tool for Early Identification of Language Impairment

ERIC Educational Resources Information Center

Uilenburg, Noëlle; Wiefferink, Karin; Verkerk, Paul; van Denderen, Margot; van Schie, Carla; Oudesluys-Murphy, Ann-Marie

2018-01-01

Purpose: A screening tool called the "VTO Language Screening Instrument" (VTO-LSI) was developed to enable more uniform and earlier detection of language impairment. This report, consisting of 2 retrospective studies, focuses on the effects of using the VTO-LSI compared to regular detection procedures. Method: Study 1 retrospectively…

Building Strategic Capabilities for Sustained Lunar Exploration

NASA Astrophysics Data System (ADS)

Landgraf, M.; Hufenbach, B.; Houdou, B.

2016-11-01

We discuss a lunar exploration architecture that addresses the strategic objective of providing access to the lunar surface. This access enables the most exciting part of the lunar exploration: building a sustained infrastructure on the lunar surface.

36 CFR Appendix to Part 1192 - Advisory Guidance

Code of Federal Regulations, 2010 CFR

2010-07-01

... requirements of the guidelines or to design vehicles for greater accessibility. Each entry is applicable to all... friction during walking varies in a complex and non-uniform way, the static coefficient of friction, which... gaits; a truly “non-slip” surface could not be negotiated. The Occupational Safety and Health...

49 CFR Appendix to Part 38 - Guidance Material

Code of Federal Regulations, 2012 CFR

2012-10-01

... understand the minimum requirements of the standards or to design vehicles for greater accessibility. Each... dynamic coefficient of friction during walking varies in a complex and non-uniform way, the static... persons with restricted gaits; a truly “non-slip” surface could not be negotiated. The Occupational Safety...

49 CFR Appendix to Part 38 - Guidance Material

Code of Federal Regulations, 2013 CFR

2013-10-01

... understand the minimum requirements of the standards or to design vehicles for greater accessibility. Each... dynamic coefficient of friction during walking varies in a complex and non-uniform way, the static... persons with restricted gaits; a truly “non-slip” surface could not be negotiated. The Occupational Safety...

36 CFR Appendix to Part 1192 - Advisory Guidance

Code of Federal Regulations, 2011 CFR

2011-07-01

... requirements of the guidelines or to design vehicles for greater accessibility. Each entry is applicable to all... friction during walking varies in a complex and non-uniform way, the static coefficient of friction, which... gaits; a truly “non-slip” surface could not be negotiated. The Occupational Safety and Health...

36 CFR Appendix to Part 1192 - Advisory Guidance

Code of Federal Regulations, 2014 CFR

2014-07-01

... requirements of the guidelines or to design vehicles for greater accessibility. Each entry is applicable to all... friction during walking varies in a complex and non-uniform way, the static coefficient of friction, which... gaits; a truly “non-slip” surface could not be negotiated. The Occupational Safety and Health...

36 CFR Appendix to Part 1192 - Advisory Guidance

Code of Federal Regulations, 2012 CFR

2012-07-01

... requirements of the guidelines or to design vehicles for greater accessibility. Each entry is applicable to all... friction during walking varies in a complex and non-uniform way, the static coefficient of friction, which... gaits; a truly “non-slip” surface could not be negotiated. The Occupational Safety and Health...

36 CFR Appendix to Part 1192 - Advisory Guidance

Code of Federal Regulations, 2013 CFR

2013-07-01

... requirements of the guidelines or to design vehicles for greater accessibility. Each entry is applicable to all... friction during walking varies in a complex and non-uniform way, the static coefficient of friction, which... gaits; a truly “non-slip” surface could not be negotiated. The Occupational Safety and Health...

49 CFR Appendix to Part 38 - Guidance Material

Code of Federal Regulations, 2011 CFR

2011-10-01

... understand the minimum requirements of the standards or to design vehicles for greater accessibility. Each... dynamic coefficient of friction during walking varies in a complex and non-uniform way, the static... persons with restricted gaits; a truly “non-slip” surface could not be negotiated. The Occupational Safety...

State Authorization Reciprocity Agreement: Participation and Access to Higher Education

ERIC Educational Resources Information Center

Onwuameze, Nkechi

2017-01-01

The State Authorization Reciprocity Agreement initiative was launched in 2014 to provide a uniform standard for the regulation of distance education across states in the United States. The system established by the National Council for State Authorization Reciprocity Agreement (NC-SARA) allows willing post-secondary institutions to participate…

20 CFR 435.53 - Retention and access requirements for records.

Code of Federal Regulations, 2013 CFR

2013-04-01

.... 435.53 Section 435.53 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE..., statistical records, and all other records pertinent to an award must be retained for a period of three years... computations of the rate at which a particular group of costs is chargeable (such as computer usage chargeback...

20 CFR 435.53 - Retention and access requirements for records.

Code of Federal Regulations, 2014 CFR

2014-04-01

.... 435.53 Section 435.53 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE..., statistical records, and all other records pertinent to an award must be retained for a period of three years... computations of the rate at which a particular group of costs is chargeable (such as computer usage chargeback...

20 CFR 435.53 - Retention and access requirements for records.

Code of Federal Regulations, 2012 CFR

2012-04-01

.... 435.53 Section 435.53 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE..., statistical records, and all other records pertinent to an award must be retained for a period of three years... computations of the rate at which a particular group of costs is chargeable (such as computer usage chargeback...

20 CFR 435.53 - Retention and access requirements for records.

Code of Federal Regulations, 2011 CFR

2011-04-01

.... 435.53 Section 435.53 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE... authorized by SSA. The only exceptions are the following: (1) If any litigation, claim, or audit is started... audit findings involving the records have been resolved and final action taken. (2) Records for real...

28 CFR 115.221 - Evidence protocol and forensic medical examinations.

Code of Federal Regulations, 2013 CFR

2013-07-01

.... Department of Justice's Office on Violence Against Women publication, “A National Protocol for Sexual Assault... for investigating allegations of sexual abuse, the agency shall follow a uniform evidence protocol... developed after 2011. (c) The agency shall offer all victims of sexual abuse access to forensic medical...

28 CFR 115.21 - Evidence protocol and forensic medical examinations.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Office on Violence Against Women publication, “A National Protocol for Sexual Assault Medical Forensic... allegations of sexual abuse, the agency shall follow a uniform evidence protocol that maximizes the potential.... (c) The agency shall offer all victims of sexual abuse access to forensic medical examinations...

28 CFR 115.221 - Evidence protocol and forensic medical examinations.

Code of Federal Regulations, 2014 CFR

2014-07-01

.... Department of Justice's Office on Violence Against Women publication, “A National Protocol for Sexual Assault... for investigating allegations of sexual abuse, the agency shall follow a uniform evidence protocol... developed after 2011. (c) The agency shall offer all victims of sexual abuse access to forensic medical...

28 CFR 115.221 - Evidence protocol and forensic medical examinations.

Code of Federal Regulations, 2012 CFR

2012-07-01

.... Department of Justice's Office on Violence Against Women publication, “A National Protocol for Sexual Assault... for investigating allegations of sexual abuse, the agency shall follow a uniform evidence protocol... developed after 2011. (c) The agency shall offer all victims of sexual abuse access to forensic medical...

28 CFR 115.21 - Evidence protocol and forensic medical examinations.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Office on Violence Against Women publication, “A National Protocol for Sexual Assault Medical Forensic... allegations of sexual abuse, the agency shall follow a uniform evidence protocol that maximizes the potential.... (c) The agency shall offer all victims of sexual abuse access to forensic medical examinations...

28 CFR 115.21 - Evidence protocol and forensic medical examinations.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Office on Violence Against Women publication, “A National Protocol for Sexual Assault Medical Forensic... allegations of sexual abuse, the agency shall follow a uniform evidence protocol that maximizes the potential.... (c) The agency shall offer all victims of sexual abuse access to forensic medical examinations...

Mobile devices and weak ties: a study of vision impairments and workplace access in Bangalore.

PubMed

Pal, Joyojeet; Lakshmanan, Meera

2015-07-01

To explore ways in which social and economic interactions are changed by access to mobile telephony. This is a mixed-methods study of mobile phone use among 52 urban professionals with vision impairments in Bangalore, India. Interviews and survey results indicated that mobile devices, specifically those with adaptive technology software, play a vital role as multi-purpose devices that enable people with disabilities to navigate economically and socially in an environment where accessibility remains a significant challenge. We found that mobile devices play a central role in enabling and sustaining weak ties, but also that these weak ties have important gender-specific implications. We found that women have less access to weak ties than men, which impacts women's access to assistive technology (AT). This has potential implications for women's sense of safety and independence, both of which are strongly related to AT access. Implications for Rehabilitation Adaptive technologies increase individuals' ability to keep in contact with casual connections or weak ties through phone calls or social media. Men tend to have stronger access to weak ties than women in India due to cultural impediments to independent access to public spaces. Weak ties are an important source of assistive technology (AT) due to the high rate of resale of used AT, typically through informal networks.

Development of an expert analysis tool based on an interactive subsidence hazard map for urban land use in the city of Celaya, Mexico

NASA Astrophysics Data System (ADS)

Alloy, A.; Gonzalez Dominguez, F.; Nila Fonseca, A. L.; Ruangsirikulchai, A.; Gentle, J. N., Jr.; Cabral, E.; Pierce, S. A.

2016-12-01

Land Subsidence as a result of groundwater extraction in central Mexico's larger urban centers initiated in the 80's as a result of population and economic growth. The city of Celaya has undergone subsidence for a few decades and a consequence is the development of an active normal fault system that affects its urban infrastructure and residential areas. To facilitate its analysis and a land use decision-making process we created an online interactive map enabling users to easily obtain information associated with land subsidence. Geological and socioeconomic data of the city was collected, including fault location, population data, and other important infrastructure and structural data has been obtained from fieldwork as part of a study abroad interchange undergraduate course. The subsidence and associated faulting hazard map was created using an InSAR derived subsidence velocity map and population data from INEGI to identify hazard zones using a subsidence gradient spatial analysis approach based on a subsidence gradient and population risk matrix. This interactive map provides a simple perspective of different vulnerable urban elements. As an accessible visualization tool, it will enhance communication between scientific and socio-economic disciplines. Our project also lays the groundwork for a future expert analysis system with an open source and easily accessible Python coded, SQLite database driven website which archives fault and subsidence data along with visual damage documentation to civil structures. This database takes field notes and provides an entry form for uniform datasets, which are used to generate a JSON. Such a database is useful because it allows geoscientists to have a centralized repository and access to their observations over time. Because of the widespread presence of the subsidence phenomena throughout cities in central Mexico, the spatial analysis has been automated using the open source software R. Raster, rgeos, shapefiles, and rgdal libraries have been used to develop the script which permits to obtain the raster maps of horizontal gradient and population density. An advantage is that this analysis can be automated for periodic updates or repurposed for similar analysis in other cities, providing an easily accessible tool for land subsidence hazard assessments.

Terrain - Umbra Package v. 1.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oppel, Fred; Hart, Brian; Rigdon, James Brian

This library contains modules that read terrain files (e.g., OpenFlight, Open Scene Graph IVE, GeoTIFF Image) and to read and manage ESRI terrain datasets. All data is stored and managed in Open Scene Graph (OSG). Terrain system accesses OSG and provides elevation data, access to meta-data such as soil types and enables linears, areals and buildings to be placed in a terrain, These geometry objects include boxes, point, path, and polygon (region), and sector modules. Utilities have been made available for clamping objects to the terrain and accessing LOS information. This assertion includes a managed C++ wrapper code (TerrainWrapper) tomore » enable C# applications, such as OpShed and UTU, to incorporate this library.« less

Provider documentation of patient education: a lean investigation*

PubMed Central

Shipman, Jean P.; Lake, Erica W.; Van Der Volgen, Jessica; Doman, Darrin

2016-01-01

Purpose The study evaluates how providers give patient education materials and identifies improvements to comply with Meaningful Use (MU) requirements. Methods Thirty-eight patient-provider interactions in two health care outpatient clinics were observed. Results Providers do not uniformly know MU patient education requirements. Providers have individual preferences and find gaps in what is available. Accessing and documenting patient education varies among providers. Embedded electronic health record (EHR) materials, while available, have technical access barriers. Conclusions Providers' EHR skills and knowledge levels contribute to non-standardized patient education delivery. PMID:27076805

An Novel Architecture of Large-scale Communication in IOT

NASA Astrophysics Data System (ADS)

Ma, Wubin; Deng, Su; Huang, Hongbin

2018-03-01

In recent years, many scholars have done a great deal of research on the development of Internet of Things and networked physical systems. However, few people have made the detailed visualization of the large-scale communications architecture in the IOT. In fact, the non-uniform technology between IPv6 and access points has led to a lack of broad principles of large-scale communications architectures. Therefore, this paper presents the Uni-IPv6 Access and Information Exchange Method (UAIEM), a new architecture and algorithm that addresses large-scale communications in the IOT.

New method to access hyperbranched polymers with uniform structure via one-pot polymerization of inimer in microemulsion.

PubMed

Min, Ke; Gao, Haifeng

2012-09-26

A facile approach is presented for successful synthesis of hyperbranched polymers with high molecular weight and uniform structure by a one-pot polymerization of an inimer in a microemulsion. The segregated space in the microemulsion confined the inimer polymerization and particularly the polymer-polymer reaction within discrete nanoparticles. At the end of polymerization, each nanoparticle contained one hyperbranched polymer that had thousands of inimer units and low polydispersity. The hyperbranched polymers were used as multifunctional macroinitiators for synthesis of "hyper-star" polymers. When a degradable inimer was applied, the hyper-stars showed fast degradation into linear polymer chains with low molecular weight.

One-Step Laser Patterned Highly Uniform Reduced Graphene Oxide Thin Films for Circuit-Enabled Tattoo and Flexible Humidity Sensor Application.

PubMed

Park, Rowoon; Kim, Hyesu; Lone, Saifullah; Jeon, Sangheon; Kwon, Young Woo; Shin, Bosung; Hong, Suck Won

2018-06-06

The conversion of graphene oxide (GO) into reduced graphene oxide (rGO) is imperative for the electronic device applications of graphene-based materials. Efficient and cost-effective fabrication of highly uniform GO films and the successive reduction into rGO on a large area is still a cumbersome task through conventional protocols. Improved film casting of GO sheets on a polymeric substrate with quick and green reduction processes has a potential that may establish a path to the practical flexible electronics. Herein, we report a facile deposition process of GO on flexible polymer substrates to create highly uniform thin films over a large area by a flow-enabled self-assembly approach. The self-assembly of GO sheets was successfully performed by dragging the trapped solution of GO in confined geometry, which consisted of an upper stationary blade and a lower moving substrate on a motorized translational stage. The prepared GO thin films could be selectively reduced and facilitated from the simple laser direct writing process for programmable circuit printing with the desired configuration and less sample damage due to the non-contact mode operation without the use of photolithography, toxic chemistry, or high-temperature reduction methods. Furthermore, two different modes of the laser operating system for the reduction of GO films turned out to be valuable for the construction of novel graphene-based high-throughput electrical circuit boards compatible with integrating electronic module chips and flexible humidity sensors.

Naval Oceanography Portal

Science.gov Websites

accessible and usable, working in accordance with the Web Content Accessibility Guidelines (WCAG v1.0). If navigation device enabling you to get around this web site using your keyboard. Available access keys This develop a web site that is clear and simple for everybody to use. Validation We have used XHTML 1.0 and

LOADING AND UNLOADING DEVICE

DOEpatents

Treshow, M.

1960-08-16

A device for loading and unloading fuel rods into and from a reactor tank through an access hole includes parallel links carrying a gripper. These links enable the gripper to go through the access hole and then to be moved laterally from the axis of the access hole to the various locations of the fuel rods in the reactor tank.

Putting a Medical Library Online: Phase III--Remote Access to CD-ROMs.

ERIC Educational Resources Information Center

Kittle, Paul

1989-01-01

Describes the implementation of a project that provides dial-up access to MEDLINE on remote optical data disk (CD-ROM) using software that enables callers to use programs like Wordstar, Lotus, and dBase. Highlights include networking CD-ROM databases, hardware considerations, advantages and disadvantages of remote access, and future plans. A…

Measuring Confidence Levels of Male and Female Students in Open Access Enabling Courses

ERIC Educational Resources Information Center

Atherton, Mirella

2015-01-01

The study of confidence was undertaken at the University of Newcastle with students selecting science courses at two campuses. The students were enrolled in open access programs and aimed to gain access to undergraduate studies in various disciplines at University. The "third person effect" was used to measure the confidence levels of…

76 FR 19357 - Emergency Access Advisory Committee; Announcement of Date of Next Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-07

... Committee will address the status of the national survey of persons with disability and seniors to learn... access to emergency services by individuals with disabilities as part of our nation's migration to a... methods by which to enable access to NG9-1-1 emergency services by individuals with disabilities. In order...

Information Power Grid (IPG) Tutorial 2003

NASA Technical Reports Server (NTRS)

Meyers, George

2003-01-01

For NASA and the general community today Grid middleware: a) provides tools to access/use data sources (databases, instruments, ...); b) provides tools to access computing (unique and generic); c) Is an enabler of large scale collaboration. Dynamically responding to needs is a key selling point of a grid. Independent resources can be joined as appropriate to solve a problem. Provide tools to enable the building of a frameworks for application. Provide value added service to the NASA user base for utilizing resources on the grid in new and more efficient ways. Provides tools for development of Frameworks.

The role of CORBA in enabling telemedicine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Forslund, D.W.

1997-07-01

One of the most powerful tools available for telemedicine is a multimedia medical record accessible over a wide area and simultaneously editable by multiple physicians. The ability to do this through an intuitive interface linking multiple distributed data repositories while maintaining full data integrity is a fundamental enabling technology in healthcare. The author discusses the role of distributed object technology using CORBA in providing this capability including an example of such a system (TeleMed) which can be accessed through the World Wide Web. Issues of security, scalability, data integrity, and useability are emphasized.

Safe Grid

NASA Technical Reports Server (NTRS)

Chow, Edward T.; Stewart, Helen; Korsmeyer, David (Technical Monitor)

2003-01-01

The biggest users of GRID technologies came from the science and technology communities. These consist of government, industry and academia (national and international). The NASA GRID is moving into a higher technology readiness level (TRL) today; and as a joint effort among these leaders within government, academia, and industry, the NASA GRID plans to extend availability to enable scientists and engineers across these geographical boundaries collaborate to solve important problems facing the world in the 21 st century. In order to enable NASA programs and missions to use IPG resources for program and mission design, the IPG capabilities needs to be accessible from inside the NASA center networks. However, because different NASA centers maintain different security domains, the GRID penetration across different firewalls is a concern for center security people. This is the reason why some IPG resources are been separated from the NASA center network. Also, because of the center network security and ITAR concerns, the NASA IPG resource owner may not have full control over who can access remotely from outside the NASA center. In order to obtain organizational approval for secured remote access, the IPG infrastructure needs to be adapted to work with the NASA business process. Improvements need to be made before the IPG can be used for NASA program and mission development. The Secured Advanced Federated Environment (SAFE) technology is designed to provide federated security across NASA center and NASA partner's security domains. Instead of one giant center firewall which can be difficult to modify for different GRID applications, the SAFE "micro security domain" provide large number of professionally managed "micro firewalls" that can allow NASA centers to accept remote IPG access without the worry of damaging other center resources. The SAFE policy-driven capability-based federated security mechanism can enable joint organizational and resource owner approved remote access from outside of NASA centers. A SAFE enabled IPG can enable IPG capabilities to be available to NASA mission design teams across different NASA center and partner company firewalls. This paper will first discuss some of the potential security issues for IPG to work across NASA center firewalls. We will then present the SAFE federated security model. Finally we will present the concept of the architecture of a SAFE enabled IPG and how it can benefit NASA mission development.

PULSION® HP: Tunable, High Productivity Plasma Doping

NASA Astrophysics Data System (ADS)

Felch, S. B.; Torregrosa, F.; Etienne, H.; Spiegel, Y.; Roux, L.; Turnbaugh, D.

2011-01-01

Plasma doping has been explored for many implant applications for over two decades and is now being used in semiconductor manufacturing for two applications: DRAM polysilicon counter-doping and contact doping. The PULSION HP is a new plasma doping tool developed by Ion Beam Services for high-volume production that enables customer control of the dominant mechanism—deposition, implant, or etch. The key features of this tool are a proprietary, remote RF plasma source that enables a high density plasma with low chamber pressure, resulting in a wide process space, and special chamber and wafer electrode designs that optimize doping uniformity.

Standardized Access and Processing of Multi-Source Earth Observation Time-Series Data within a Regional Data Middleware

NASA Astrophysics Data System (ADS)

Eberle, J.; Schmullius, C.

2017-12-01

Increasing archives of global satellite data present a new challenge to handle multi-source satellite data in a user-friendly way. Any user is confronted with different data formats and data access services. In addition the handling of time-series data is complex as an automated processing and execution of data processing steps is needed to supply the user with the desired product for a specific area of interest. In order to simplify the access to data archives of various satellite missions and to facilitate the subsequent processing, a regional data and processing middleware has been developed. The aim of this system is to provide standardized and web-based interfaces to multi-source time-series data for individual regions on Earth. For further use and analysis uniform data formats and data access services are provided. Interfaces to data archives of the sensor MODIS (NASA) as well as the satellites Landsat (USGS) and Sentinel (ESA) have been integrated in the middleware. Various scientific algorithms, such as the calculation of trends and breakpoints of time-series data, can be carried out on the preprocessed data on the basis of uniform data management. Jupyter Notebooks are linked to the data and further processing can be conducted directly on the server using Python and the statistical language R. In addition to accessing EO data, the middleware is also used as an intermediary between the user and external databases (e.g., Flickr, YouTube). Standardized web services as specified by OGC are provided for all tools of the middleware. Currently, the use of cloud services is being researched to bring algorithms to the data. As a thematic example, an operational monitoring of vegetation phenology is being implemented on the basis of various optical satellite data and validation data from the German Weather Service. Other examples demonstrate the monitoring of wetlands focusing on automated discovery and access of Landsat and Sentinel data for local areas.

Agarose droplet microfluidics for highly parallel and efficient single molecule emulsion PCR.

PubMed

Leng, Xuefei; Zhang, Wenhua; Wang, Chunming; Cui, Liang; Yang, Chaoyong James

2010-11-07

An agarose droplet method was developed for highly parallel and efficient single molecule emulsion PCR. The method capitalizes on the unique thermoresponsive sol-gel switching property of agarose for highly efficient DNA amplification and amplicon trapping. Uniform agarose solution droplets generated via a microfluidic chip serve as robust and inert nanolitre PCR reactors for single copy DNA molecule amplification. After PCR, agarose droplets are gelated to form agarose beads, trapping all amplicons in each reactor to maintain the monoclonality of each droplet. This method does not require cocapsulation of primer labeled microbeads, allows high throughput generation of uniform droplets and enables high PCR efficiency, making it a promising platform for many single copy genetic studies.

Electrohydrodynamic printing for scalable MoS2 flake coating: application to gas sensing device

NASA Astrophysics Data System (ADS)

Lim, Sooman; Cho, Byungjin; Bae, Jaehyun; Kim, Ah Ra; Lee, Kyu Hwan; Kim, Se Hyun; Hahm, Myung Gwan; Nam, Jaewook

2016-10-01

Scalable sub-micrometer molybdenum disulfide ({{MoS}}2) flake films with highly uniform coverage were created using a systematic approach. An electrohydrodynamic (EHD) printing process realized a remarkably uniform distribution of exfoliated {{MoS}}2 flakes on desired substrates. In combination with a fast evaporating dispersion medium and an optimal choice of operating parameters, the EHD printing can produce a film rapidly on a substrate without excessive agglomeration or cluster formation, which can be problems in previously reported liquid-based continuous film methods. The printing of exfoliated {{MoS}}2 flakes enabled the fabrication of a gas sensor with high performance and reproducibility for {{NO}}2 and {{NH}}3.

Barriers and enablers to healthcare access and use among Arabic-speaking and Caucasian English-speaking patients with type 2 diabetes mellitus: a qualitative comparative study.

PubMed

Alzubaidi, H; Mc Namara, K; Browning, Colette; Marriott, J

2015-11-17

The objective of this study was to explore the decision-making processes and associated barriers and enablers that determine access and use of healthcare services in Arabic-speaking and English-speaking Caucasian patients with diabetes in Australia. Face-to-face semistructured individual interviews and group interviews were conducted at various healthcare settings-diabetes outpatient clinics in 2 tertiary referral hospitals, 6 primary care practices and 10 community centres in Melbourne, Australia. A total of 100 participants with type 2 diabetes mellitus were recruited into 2 groups: 60 Arabic-speaking and 40 English-speaking Caucasian. Interviews were audio-taped, translated into English when necessary, transcribed and coded thematically. Sociodemographic and clinical information was gathered using a self-completed questionnaire and medical records. Only Arabic-speaking migrants intentionally delayed access to healthcare services when obvious signs of diabetes were experienced, missing opportunities to detect diabetes at an early stage. Four major barriers and enablers to healthcare access and use were identified: influence of significant other(s), unique sociocultural and religious beliefs, experiences with healthcare providers and lack of knowledge about healthcare services. Compared with Arabic-speaking migrants, English-speaking participants had no reluctance to access and use medical services when signs of ill-health appeared; their treatment-seeking behaviours were straightforward. Arabic-speaking migrants appear to intentionally delay access to medical services even when symptomatic. Four barriers to health services access have been identified. Tailored interventions must be developed for Arabic-speaking migrants to improve access to available health services, facilitate timely diagnosis of diabetes and ultimately to improve glycaemic control. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

DEFENSE RTD&E ONLINE SYSTEM (DROLS)

EPA Science Inventory

Web Enabled DROLS (WED) is a free subscription service available to registered users that provides online access to DTIC's Technical Reports and Research Summaries Databases. It replaces the former unclassified dial-up access to DROLS, DTIC's Defense RDT&E Online System. The Defe...

Assess to Public Meetings [and] Assistive Listening Devices (ALD'S) [and] Access to Printed Information by Visually-Impaired Persons. Technical Assistance Guides.

ERIC Educational Resources Information Center

Department of Justice, Washington, DC. Civil Rights Div.

This item consists of three separate "Technical Assistance Guides" combined into one document because they all are concerned with improving access to information for handicapped people. Specifically, the three guides provide: (1) information to enable hearing impaired, visually impaired, and mobility impaired persons to have access to public…

Accessing Social Grants to Meet Orphan Children School Needs: Namibia and South Africa Perspective

ERIC Educational Resources Information Center

Taukeni, Simon; Matshidiso, Taole

2013-01-01

In this comparative paper we interrogate the access of social grants to meet orphan children school needs in Namibia and South Africa. We noted that the two governments are committed to provide orphan children with social grants to enable them to meet the school needs. However, accessing social grant to benefit most vulnerable orphan children…

Cal OES Internet Home Cal OES Home

Science.gov Websites

Sign In You may be trying to access this site from a secured browser on the server. Please enable scripts and reload this page. Turn on more accessible mode Turn off more accessible mode Skip Ribbon Commands Skip to main content Turn off Animations Turn on Animations image of CA.gov logo image of Cal OES

Space Nuclear Power Systems

NASA Technical Reports Server (NTRS)

Houts, Michael G.

2012-01-01

Fission power and propulsion systems can enable exciting space exploration missions. These include bases on the moon and Mars; and the exploration, development, and utilization of the solar system. In the near-term, fission surface power systems could provide abundant, constant, cost-effective power anywhere on the surface of the Moon or Mars, independent of available sunlight. Affordable access to Mars, the asteroid belt, or other destinations could be provided by nuclear thermal rockets. In the further term, high performance fission power supplies could enable both extremely high power levels on planetary surfaces and fission electric propulsion vehicles for rapid, efficient cargo and crew transfer. Advanced fission propulsion systems could eventually allow routine access to the entire solar system. Fission systems could also enable the utilization of resources within the solar system.

Security in Distributed Collaborative Environments: Limitations and Solutions

NASA Astrophysics Data System (ADS)

Saadi, Rachid; Pierson, Jean-Marc; Brunie, Lionel

The main goal of establishing collaboration between heterogeneous environment is to create such as Pervasive context which provide nomadic users with ubiquitous access to digital information and surrounding resources. However, the constraints of mobility and heterogeneity arise a number of crucial issues related to security, especially authentication access control and privacy. First of all, in this chapter we explore the trust paradigm, specially the transitive capability to enable a trust peer to peer collaboration. In this manner, when each organization sets its own security policy to recognize (authenticate) users members of a trusted community and provide them a local access (access control), the trust transitivity between peers will allows users to gain a broad, larger and controlled access inside the pervasive environment. Next, we study the problem of user's privacy. In fact in pervasive and ubiquitous environments, nomadic users gather and exchange certificates or credential which providing them rights to access by transitivity unknown and trusted environments. These signed documents embeds increasing number of attribute that require to be filtered according to such contextual situation. In this chapter, we propose a new morph signature enabling each certificate owner to preserve his privacy by discloses or blinds some sensitive attributes according to faced situation.

Navigating the poverty of heroin addiction treatment and recovery opportunity in Kenya: access work, self-care and rationed expectations.

PubMed

Rhodes, Tim; Ndimbii, James; Guise, Andy; Cullen, Lucy; Ayon, Sylvia

2015-01-01

Drawing on the analyses of qualitative interview accounts of people who inject heroin in Kenya, we describe the narration of addiction treatment access and recovery desire in conditions characterised by a 'poverty of drug treatment opportunity'. We observe the performance of addiction recovery narrative in the face of heavy social constraints limiting access to care. Fee-based residential rehabilitation ('rehab') is the only treatment locally available and inaccessible to most. Its recovery potential is doubted, given normative expectations of relapse. Treating drug use is a product of tightly bounded agency. Individuals enact strategies to maximise their slim chances of treatment access ('access work'), develop self-care alternatives when these fail to materialise and ration their care expectations. The use of rehab as a primary means of respite and harm reduction rather than recovery and the individuation of care in the absence of an enabling recovery environment are key characteristics of drug treatment experience. The recent incorporation of 'harm reduction' into policy discourses may trouble the primacy of recovery narrative in addiction treatment and in how treatment desires are voiced. The diversification of drug treatments in combination with social interventions enabling their access are fundamental.

Considerations on private human access to space from an institutional point of view

NASA Astrophysics Data System (ADS)

Hufenbach, Bernhard

2013-12-01

Private human access to space as discussed in this article addresses two market segments: suborbital flight and crew flights to Low Earth Orbit. The role of entrepreneurs, the technical complexity, the customers, the market conditions as well as the time to market in these two segments differ significantly. Space agencies take currently a very different approach towards private human access to space in both segments. Analysing the outcome of broader inter-agency deliberations on the future of human spaceflight and exploration, performed e.g. in the framework of the International Space Exploration Coordination Group, enables to derive some common general views on this topic. Various documents developed by inter-agency working groups recognise the general strategic importance for enabling private human access to space for ensuring a sustainable future of human spaceflight, although the specific definition of private human access and approaches vary. ESA has performed some reflections on this subject throughout the last 5 years. While it gained through these reflections a good understanding on the opportunities and implications resulting from the development of capabilities and markets for Private Human Access, limited concrete activities have been initiated in relation to this topic as of today.

Stable discrete representation of relativistically drifting plasmas

DOE PAGES

Kirchen, M.; Lehe, R.; Godfrey, B. B.; ...

2016-10-10

Representing the electrodynamics of relativistically drifting particle ensembles in discrete, co-propagating Galilean coordinates enables the derivation of a Particle-In-Cell algorithm that is intrinsically free of the numerical Cherenkov instability for plasmas flowing at a uniform velocity. Application of the method is shown by modeling plasma accelerators in a Lorentz-transformed optimal frame of reference.

77 FR 75894 - Telecommunications Relay Services and Speech-to-Speech Services for Individuals With Hearing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-26

... Individuals With Hearing and Speech Disabilities; E911 Requirements for IP-Enabled Service Providers AGENCY... no uniform numbering system for iTRS services; some iTRS users were reached via an IP address, while...-digit number and his IP address, making it relatively traceable (unlike conventional PSTN spoofing...

Stable discrete representation of relativistically drifting plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kirchen, M.; Lehe, R.; Godfrey, B. B.

Representing the electrodynamics of relativistically drifting particle ensembles in discrete, co-propagating Galilean coordinates enables the derivation of a Particle-In-Cell algorithm that is intrinsically free of the numerical Cherenkov instability for plasmas flowing at a uniform velocity. Application of the method is shown by modeling plasma accelerators in a Lorentz-transformed optimal frame of reference.

Ensuring Program Uniformity at the Hearing and Appeals Council Levels of the Administrative Review Process. Final rule.

PubMed

2016-12-16

We are revising our rules so that more of our procedures at the hearing and Appeals Council levels of our administrative review process are consistent nationwide. We anticipate that these nationally consistent procedures will enable us to administer our disability programs more efficiently and better serve the public.

78 FR 63458 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-24

..., access to conduct research involving DoDEA students, staff, parents or data. Additionally will establish researcher accountability, enable future contact with researchers, and support preparation of statistical and... students, staff, parents or data. To establish researcher accountability, enable future contact with...

17 CFR 232.10 - Application of part 232.

Code of Federal Regulations, 2010 CFR

2010-04-01

... uniform application form for access codes to file on EDGAR, and (2) File, by uploading as a Portable... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Application of part 232. 232...-T-GENERAL RULES AND REGULATIONS FOR ELECTRONIC FILINGS General § 232.10 Application of part 232. (a...

ScienceDesk Project Overview

NASA Technical Reports Server (NTRS)

Keller, Richard M.; Norvig, Peter (Technical Monitor)

2000-01-01

NASA's ScienceDesk Project at the Ames Research Center is responsible for scientific knowledge management which includes ensuring the capture, preservation, and traceability of scientific knowledge. Other responsibilities include: 1) Maintaining uniform information access which is achieved through intelligent indexing and visualization, 2) Collaborating both asynchronous and synchronous science teamwork, 3) Monitoring and controlling semi-autonomous remote experimentation.

Redefining School Health Services: Comprehensive Child Health Care as the Framework.

ERIC Educational Resources Information Center

Silver, George A.

Recognizing the needs, deficiencies, and diversity of school health services is prerequisite to any analysis of need. More uniform programs and more equitable access for all school children to whatever minimal standard of health services should be provided: periodic examination, some limited medical care on the school grounds, intensive health…

Simple Search Aids with a Little Help from My Friends

ERIC Educational Resources Information Center

Spitzer, Stephan

2008-01-01

The Uniformed Services University of the Health Sciences, located on the National Naval Medical Center's campus in Bethesda, Md., is a medical education and research facility for the nation's military and public health community. The university's James A. Zimble Learning Resource Center provides web-based access to more than 9,000 electronic…

17 CFR 259.602 - Form ID, uniform application for access codes to file on EDGAR.

Code of Federal Regulations, 2011 CFR

2011-04-01

...)—allows a filer, filing agent or training agent to log on to the EDGAR system, submit filings, and change... agent to change its Password. [69 FR 22710, Apr. 26, 2004] Editorial Note: For Federal Register... section of the printed volume and at at www.fdsys.gov. ...

Isochoric Implosions for Fast Ignition

NASA Astrophysics Data System (ADS)

Clark, Daniel; Tabak, Max

2006-10-01

Various gain models have shown the potentially great advantages of Fast Ignition (FI) Inertial Confinement Fusion (ICF) over its conventional hotspot ignition counterpart. These gain models, however, all assume nearly uniform-density fuel assemblies. By contrast, typical ICF implosions yield hollowed fuel assemblies with a high-density shell of fuel surrounding a low-density, high-pressure hotspot. To realize fully the advantages of FI, then, an alternative implosion design must be found which yields nearly isochoric fuel assemblies without substantial hotspots. Here, it is shown that a self-similar spherical implosion of the type originally studied by Guderley [Luftfahrtforschung 19, 302 (1942)] may be employed to yield precisely such quasi-isochoric imploded states. The difficulty remains, however, of accessing these self-similarly imploding configurations from initial conditions representing an actual ICF target, namely a uniform, solid-density shell at rest. Furthermore, these specialized implosions must be realized for practicable drive parameters, i.e., accessible peak pressures, shell aspect ratios, etc. An implosion scheme is presented which meets all of these requirements, suggesting the possibility of genuinely isochoric implosions for FI.

Improvement of 19F MR image uniformity in a mouse model of cellular therapy using inductive coupling.

PubMed

Park, Bu S; Ma, Ge; Koch, William T; Rajan, Sunder S; Mastromanolis, Manuel; Lam, Johnny; Sung, Kyung; McCright, Brent

2018-06-15

Improve 19 F magnetic resonance imaging uniformity of perfluorocarbon (PFC)-labeled cells by using a secondary inductive resonator tuned to 287 MHz to enhance the induced radio frequency (RF) magnetic field (B 1 ) at 7.05 T. Following Faraday's induction law, the sign of induced B 1 made by the secondary resonator can be changed depending on the tuning of the resonator. A secondary resonator located on the opposite side of the phantom of the 19 F surface coil can be shown to enhance or subtract the induced B 1 field, depending upon its tuning. The numerical simulation results of rotating transmit B 1 magnitude (|B 1 + |) and corresponding experimental 19 F images were compared without and with the secondary resonator. With the secondary resonator tuned to 287 MHz, improvements of |B 1 + | and 19 F image uniformity were demonstrated. The use of the secondary resonator improved our ability to visualize transplanted cell location non-invasively over a period of 6 weeks. The secondary resonator tuned to enhance the induced B 1 results in improved image uniformity in a pre-clinical application, enabling cell tracking of PFC-labeled cells with the secondary resonator.

Social Media, Power, and the Future of VBAC.

PubMed

Romano, Amy M; Gerber, Hilary; Andrews, Desirre

2010-01-01

The Internet has been called a disruptive technology because it has shifted power and altered the economics of doing business, whether that business is selling books or providing health care. Social media have accelerated the pace of disruption by enabling interactive information sharing and blurring the lines between the "producers" and "consumers" of knowledge, goods, and services. In the wake of the National Institutes of Health Consensus Development Conference on Vaginal Birth After Cesarean (VBAC) and major national recommendations for maternity care reform, activated, engaged consumers face an unprecedented opportunity to drive meaningful changes in VBAC access and safety. This article examines the role of social networks in informing women about VBAC, producing low-cost, accessible decision aids, and enabling multi-stakeholder collaborations toward workable solutions that remove barriers women face in accessing VBAC.

Computational neuroanatomy: ontology-based representation of neural components and connectivity.

PubMed

Rubin, Daniel L; Talos, Ion-Florin; Halle, Michael; Musen, Mark A; Kikinis, Ron

2009-02-05

A critical challenge in neuroscience is organizing, managing, and accessing the explosion in neuroscientific knowledge, particularly anatomic knowledge. We believe that explicit knowledge-based approaches to make neuroscientific knowledge computationally accessible will be helpful in tackling this challenge and will enable a variety of applications exploiting this knowledge, such as surgical planning. We developed ontology-based models of neuroanatomy to enable symbolic lookup, logical inference and mathematical modeling of neural systems. We built a prototype model of the motor system that integrates descriptive anatomic and qualitative functional neuroanatomical knowledge. In addition to modeling normal neuroanatomy, our approach provides an explicit representation of abnormal neural connectivity in disease states, such as common movement disorders. The ontology-based representation encodes both structural and functional aspects of neuroanatomy. The ontology-based models can be evaluated computationally, enabling development of automated computer reasoning applications. Neuroanatomical knowledge can be represented in machine-accessible format using ontologies. Computational neuroanatomical approaches such as described in this work could become a key tool in translational informatics, leading to decision support applications that inform and guide surgical planning and personalized care for neurological disease in the future.

Petaminer: Using ROOT for efficient data storage in MySQL database

NASA Astrophysics Data System (ADS)

Cranshaw, J.; Malon, D.; Vaniachine, A.; Fine, V.; Lauret, J.; Hamill, P.

2010-04-01

High Energy and Nuclear Physics (HENP) experiments store Petabytes of event data and Terabytes of calibration data in ROOT files. The Petaminer project is developing a custom MySQL storage engine to enable the MySQL query processor to directly access experimental data stored in ROOT files. Our project is addressing the problem of efficient navigation to PetaBytes of HENP experimental data described with event-level TAG metadata, which is required by data intensive physics communities such as the LHC and RHIC experiments. Physicists need to be able to compose a metadata query and rapidly retrieve the set of matching events, where improved efficiency will facilitate the discovery process by permitting rapid iterations of data evaluation and retrieval. Our custom MySQL storage engine enables the MySQL query processor to directly access TAG data stored in ROOT TTrees. As ROOT TTrees are column-oriented, reading them directly provides improved performance over traditional row-oriented TAG databases. Leveraging the flexible and powerful SQL query language to access data stored in ROOT TTrees, the Petaminer approach enables rich MySQL index-building capabilities for further performance optimization.

The Big Challenge in Big Earth Science Data: Maturing to Transdisciplinary Data Platforms that are Relevant to Government, Research and Industry

NASA Astrophysics Data System (ADS)

Wyborn, Lesley; Evans, Ben

2016-04-01

Collecting data for the Earth Sciences has a particularly long history going back centuries. Initially scientific data came only from simple human observations recorded by pen on paper. Scientific instruments soon supplemented data capture, and as these instruments became more capable (e.g, automation, more information captured, generation of digitally-born outputs), Earth Scientists entered the 'Big Data' era where progressively data became too big to store and process locally in the old style vaults. To date, most funding initiatives for collection and storage of large volume data sets in the Earth Sciences have been specialised within a single discipline (e.g., climate, geophysics, and Earth Observation) or specific to an individual institution. To undertake interdisciplinary research, it is hard for users to integrate data from these individual repositories mainly due to limitations on physical access to/movement of the data, and/or data being organised without enough information to make sense of it without discipline specialised knowledge. Smaller repositories have also gradually been seen as inefficient in terms of the cost to manage and access (including scarce skills) and effective implementation of new technology and techniques. Within the last decade, the trend is towards fewer and larger data repositories that increasingly are collocated with HPC/cloud resources. There has also been a growing recognition that digital data can be a valuable resource that can be reused and repurposed - publicly funded data from either the academic of government sector is seen as a shared resource, and that efficiencies can be gained by co-location. These new, highly capable, 'transdisciplinary' data repositories are emerging as a fundamental 'infrastructure' both for research and other innovation. The sharing of academic and government data resources on the same infrastructures is enabling new research programmes that will enable integration beyond the traditional physical scientific domain silos, including into the humanities and social sciences. Furthermore there is increasing desire for these 'Big Data' data infrastructures to prove their value not only as platforms for scientific discovery, but to also support the development of evidence-based government policies, economic growth, and private-sector opportunities. The capacity of these transdisciplinary data repositories leads to many new exciting opportunities for the next generation of large-scale data integration, but there is an emerging suite of data challenges that now need to be tackled. Many large volume data sets have historically been developed within traditional domain silos and issues such as difference of standards (informal and formal), the data conventions, the lack of controlled or even uniform vocabularies, the non-existent/not machine-accessible semantic information, and bespoke or unclear copyrights and licensing are becoming apparent. The different perspectives and approaches of the various communities have also started to come to the fore; particularly the dominant file based approach of the big data generating science communities versus the database approach of the point observational communities; and the multidimensional approach of the climate and oceans community versus the traditional 2D approach of the GIS/spatial community. Addressing such challenges is essential to fully unlock online access to all relevant data to enable the maturing of research to the transdisciplinary paradigm.

Detachable clamps for minimal access surgery.

PubMed

Frank, T; Willetts, G J; Cuschieri, A

1995-01-01

A detachable clamp and applicator have been developed for use in minimal access surgical operations involving hollow visceral transection and anastomosis. The clamp has parallel jaws which ensure uniform distribution of the occlusive force. Following application on the bowel, the clamp is released from the applicator, thus freeing the access port. On completion of the anastomosis, the clamp is docked to the applicator, its jaws opened for release from the bowel and then closed prior to removal. The jaws of the clamp are kept closed by a pseudoelastic nickel-titanium (NiTi) alloy spring which imparts advantageous force characteristics when compared to stainless steel. The excellent holding and atraumatic characteristics of the detachable clamp have been confirmed by use in laparoscopic and thoracoscopic surgery on the gastrointestinal tract.

Enhancing Return from Lunar Surface Missions via the Deep Space Gateway

NASA Astrophysics Data System (ADS)

Chavers, D. G.; Whitley, R. J.; Percy, T. K.; Needham, D. H.; Polsgrove, T. T.

2018-02-01

The Deep Space Gateway (DSG) will facilitate access to and communication with lunar surface assets. With a science airlock, docking port, and refueling capability in an accessible orbit, the DSG will enable high priority science across the lunar surface.

A concise history of central venous access.

PubMed

Beheshti, Michael V

2011-12-01

Central venous access has become a mainstay of modern interventional radiology practice. Its history has paralleled and enabled many current medical therapies. This short overview provides an interesting historical perspective of these increasingly common interventional procedures. Copyright © 2011 Elsevier Inc. All rights reserved.

Kenai Fjords National Park Over-the-Snow Transportation Feasibility Study.

DOT National Transportation Integrated Search

2012-01-31

Kenai Fjords National Park seeks to expand winter access to the Exit Glacier Area. Year-round access would better enable the park to accomplish its mission related to visitor experience, education, and research. The road to the area is inaccessible t...

Food insecurity and low self-efficacy are associated with health care access barriers among Puerto-Ricans with type 2 diabetes.

PubMed

Kollannoor-Samuel, Grace; Vega-López, Sonia; Chhabra, Jyoti; Segura-Pérez, Sofia; Damio, Grace; Pérez-Escamilla, Rafael

2012-08-01

Racial/ethnic minorities are disproportionately affected by barriers to health care access and utilization. The primary objective was to test for an independent association between household food insecurity and health care access/utilization. In this cross-sectional survey, 211 Latinos (predominantly, Puerto-Ricans) with type 2 diabetes (T2D) were interviewed at their homes. Factor analyses identified four barriers for health care access/utilization: enabling factor, doctor access, medication access and forgetfulness. Multivariate logistic regression models examined the association between each of the barrier factors and food insecurity controlling for sociodemographic, cultural, psychosocial, and diabetes self-care variables. Higher food insecurity score was a risk factor for experiencing enabling factor (OR = 1.46; 95% CI = 1.17-1.82), medication access (OR = 1.26; 95 CI% = 1.06-1.50), and forgetfulness (OR = 1.22; 95 CI% = 1.04-1.43) barriers. Higher diabetes management self-efficacy was protective against all four barriers. Other variables associated with one or more barriers were health insurance, perceived health, depression, blood glucose, age and education. Findings suggest that addressing barriers such as food insecurity, low self-efficacy, lack of health insurance, and depression could potentially result in better health care access and utilization among low income Puerto-Ricans with T2D.

Enabling Tussle-Agile Inter-networking Architectures by Underlay Virtualisation

NASA Astrophysics Data System (ADS)

Dianati, Mehrdad; Tafazolli, Rahim; Moessner, Klaus

In this paper, we propose an underlay inter-network virtualisation framework in order to enable tussle-agile flexible networking over the existing inter-network infrastructures. The functionalities that inter-networking elements (transit nodes, access networks, etc.) need to support in order to enable virtualisation are discussed. We propose the base architectures of each the abstract elements to support the required inter-network virtualisation functionalities.

A survey of enabling technologies in synthetic biology

PubMed Central

2013-01-01

Background Realizing constructive applications of synthetic biology requires continued development of enabling technologies as well as policies and practices to ensure these technologies remain accessible for research. Broadly defined, enabling technologies for synthetic biology include any reagent or method that, alone or in combination with associated technologies, provides the means to generate any new research tool or application. Because applications of synthetic biology likely will embody multiple patented inventions, it will be important to create structures for managing intellectual property rights that best promote continued innovation. Monitoring the enabling technologies of synthetic biology will facilitate the systematic investigation of property rights coupled to these technologies and help shape policies and practices that impact the use, regulation, patenting, and licensing of these technologies. Results We conducted a survey among a self-identifying community of practitioners engaged in synthetic biology research to obtain their opinions and experiences with technologies that support the engineering of biological systems. Technologies widely used and considered enabling by survey participants included public and private registries of biological parts, standard methods for physical assembly of DNA constructs, genomic databases, software tools for search, alignment, analysis, and editing of DNA sequences, and commercial services for DNA synthesis and sequencing. Standards and methods supporting measurement, functional composition, and data exchange were less widely used though still considered enabling by a subset of survey participants. Conclusions The set of enabling technologies compiled from this survey provide insight into the many and varied technologies that support innovation in synthetic biology. Many of these technologies are widely accessible for use, either by virtue of being in the public domain or through legal tools such as non-exclusive licensing. Access to some patent protected technologies is less clear and use of these technologies may be subject to restrictions imposed by material transfer agreements or other contract terms. We expect the technologies considered enabling for synthetic biology to change as the field advances. By monitoring the enabling technologies of synthetic biology and addressing the policies and practices that impact their development and use, our hope is that the field will be better able to realize its full potential. PMID:23663447

Proximity-based access control for context-sensitive information provision in SOA-based systems

NASA Astrophysics Data System (ADS)

Rajappan, Gowri; Wang, Xiaofei; Grant, Robert; Paulini, Matthew

2014-06-01

Service Oriented Architecture (SOA) has enabled open-architecture integration of applications within an enterprise. For net-centric Command and Control (C2), this elucidates information sharing between applications and users, a critical requirement for mission success. The Information Technology (IT) access control schemes, which arbitrate who gets access to what information, do not yet have the contextual knowledge to dynamically allow this information sharing to happen dynamically. The access control might prevent legitimate users from accessing information relevant to the current mission context, since this context may be very different from the context for which the access privileges were configured. We evaluate a pair of data relevance measures - proximity and risk - and use these as the basis of dynamic access control. Proximity is a measure of the strength of connection between the user and the resource. However, proximity is not sufficient, since some data might have a negative impact, if leaked, which far outweighs importance to the subject's mission. For this, we use a risk measure to quantify the downside of data compromise. Given these contextual measures of proximity and risk, we investigate extending Attribute-Based Access Control (ABAC), which is used by the Department of Defense, and Role-Based Access Control (RBAC), which is widely used in the civilian market, so that these standards-based access control models are given contextual knowledge to enable dynamic information sharing. Furthermore, we consider the use of such a contextual access control scheme in a SOA-based environment, in particular for net-centric C2.

Web-Enabled Systems for Student Access.

ERIC Educational Resources Information Center

Harris, Chad S.; Herring, Tom

1999-01-01

California State University, Fullerton is developing a suite of server-based, Web-enabled applications that distribute the functionality of its student information system software to external customers without modifying the mainframe applications or databases. The cost-effective, secure, and rapidly deployable business solution involves using the…

Self-assembly of ordered graphene nanodot arrays

DOE PAGES

Camilli, Luca; Jørgensen, Jakob H.; Tersoff, Jerry; ...

2017-06-29

Our ability to fabricate nanoscale domains of uniform size in two-dimensional materials could potentially enable new applications in nanoelectronics and the development of innovative metamaterials. But, achieving even minimal control over the growth of two-dimensional lateral heterostructures at such extreme dimensions has proven exceptionally challenging. Here we show the spontaneous formation of ordered arrays of graphene nano-domains (dots), epitaxially embedded in a two-dimensional boron–carbon–nitrogen alloy. These dots exhibit a strikingly uniform size of 1.6 ± 0.2 nm and strong ordering, and the array periodicity can be tuned by adjusting the growth conditions. Furthemore, we explain this behaviour with a modelmore » incorporating dot-boundary energy, a moiré-modulated substrate interaction and a long-range repulsion between dots. This new two-dimensional material, which theory predicts to be an ordered composite of uniform-size semiconducting graphene quantum dots laterally integrated within a larger-bandgap matrix, holds promise for novel electronic and optoelectronic properties, with a variety of potential device applications.« less

Stress Analysis of Composite Cylindrical Shells with an Elliptical Cutout

NASA Technical Reports Server (NTRS)

Oterkus, E.; Madenci, E.; Nemeth, M. P.

2007-01-01

A special-purpose, semi-analytical solution method for determining the stress and deformation fields in a thin laminated-composite cylindrical shell with an elliptical cutout is presented. The analysis includes the effects of cutout size, shape, and orientation; non-uniform wall thickness; oval-cross-section eccentricity; and loading conditions. The loading conditions include uniform tension, uniform torsion, and pure bending. The analysis approach is based on the principle of stationary potential energy and uses Lagrange multipliers to relax the kinematic admissibility requirements on the displacement representations through the use of idealized elastic edge restraints. Specifying appropriate stiffness values for the elastic extensional and rotational edge restraints (springs) allows the imposition of the kinematic boundary conditions in an indirect manner, which enables the use of a broader set of functions for representing the displacement fields. Selected results of parametric studies are presented for several geometric parameters that demonstrate that analysis approach is a powerful means for developing design criteria for laminated-composite shells.

Uniform hexagonal graphene flakes and films grown on liquid copper surface.

PubMed

Geng, Dechao; Wu, Bin; Guo, Yunlong; Huang, Liping; Xue, Yunzhou; Chen, Jianyi; Yu, Gui; Jiang, Lang; Hu, Wenping; Liu, Yunqi

2012-05-22

Unresolved problems associated with the production of graphene materials include the need for greater control over layer number, crystallinity, size, edge structure and spatial orientation, and a better understanding of the underlying mechanisms. Here we report a chemical vapor deposition approach that allows the direct synthesis of uniform single-layered, large-size (up to 10,000 μm(2)), spatially self-aligned, and single-crystalline hexagonal graphene flakes (HGFs) and their continuous films on liquid Cu surfaces. Employing a liquid Cu surface completely eliminates the grain boundaries in solid polycrystalline Cu, resulting in a uniform nucleation distribution and low graphene nucleation density, but also enables self-assembly of HGFs into compact and ordered structures. These HGFs show an average two-dimensional resistivity of 609 ± 200 Ω and saturation current density of 0.96 ± 0.15 mA/μm, demonstrating their good conductivity and capability for carrying high current density.

Uniform hexagonal graphene flakes and films grown on liquid copper surface

PubMed Central

Geng, Dechao; Wu, Bin; Guo, Yunlong; Huang, Liping; Xue, Yunzhou; Chen, Jianyi; Yu, Gui; Jiang, Lang; Hu, Wenping; Liu, Yunqi

2012-01-01

Unresolved problems associated with the production of graphene materials include the need for greater control over layer number, crystallinity, size, edge structure and spatial orientation, and a better understanding of the underlying mechanisms. Here we report a chemical vapor deposition approach that allows the direct synthesis of uniform single-layered, large-size (up to 10,000 μm2), spatially self-aligned, and single-crystalline hexagonal graphene flakes (HGFs) and their continuous films on liquid Cu surfaces. Employing a liquid Cu surface completely eliminates the grain boundaries in solid polycrystalline Cu, resulting in a uniform nucleation distribution and low graphene nucleation density, but also enables self-assembly of HGFs into compact and ordered structures. These HGFs show an average two-dimensional resistivity of 609 ± 200 Ω and saturation current density of 0.96 ± 0.15 mA/μm, demonstrating their good conductivity and capability for carrying high current density. PMID:22509001

Public participation and marginalized groups: the community development model.

PubMed

O'Keefe, Eileen; Hogg, Christine

1999-12-01

OBJECTIVES: To develop ways of reaching house-bound people and enabling them to give their views in planning and monitoring health and social care. STRATEGY: HealthLINK - a project based in a community health council - explored ways of involving older house-bound people in the London Borough of Camden, in planning and monitoring health and social care using community development techniques. RESULTS: HealthLINK set up an infrastructure to enable house-bound people to have access to information and to enable them to give their views. This resulted in access for health and local authorities to the views of house-bound older people and increased the self esteem and quality of life of those who became involved. CONCLUSIONS: Community development approaches that enable an infrastructure to be established may be an effective way of reaching marginalized communities. However, there are tensions in this approach between the different requirements for public involvement of statutory bodies and of users, and between representation of groups and listening to individual voices.

ScienceOrganizer System and Interface Summary

NASA Technical Reports Server (NTRS)

Keller, Richard M.; Norvig, Peter (Technical Monitor)

2001-01-01

ScienceOrganizer is a specialized knowledge management tool designed to enhance the information storage, organization, and access capabilities of distributed NASA science teams. Users access ScienceOrganizer through an intuitive Web-based interface that enables them to upload, download, and organize project information - including data, documents, images, and scientific records associated with laboratory and field experiments. Information in ScienceOrganizer is "threaded", or interlinked, to enable users to locate, track, and organize interrelated pieces of scientific data. Linkages capture important semantic relationships among information resources in the repository, and these assist users in navigating through the information related to their projects.

Evaluation of Standards for Access Control Enabling PHR-S Federation.

PubMed

Mense, Alexander; Urbauer, Philipp; Sauermann, Stefan

2017-01-01

The adoption of the Internet of Things (IoT) and mobile applications in the healthcare may transform the healthcare industry by offering better disease tracking and management as well as patient empowerment. Unfortunately, almost all of these new systems set up their own ecosystem and to be really valuable for the care process they need to be integrated or federated with user managed access control services based on international standards and profiles to enable interoperability. Thus, this work presents the results of an evaluation of available specifications for federated authorization, based on a set of basic requirements.

Accurate SERS detection of malachite green in aquatic products on basis of graphene wrapped flexible sensor.

PubMed

Ouyang, Lei; Yao, Ling; Zhou, Taohong; Zhu, Lihua

2018-10-16

Malachite Green (MG) is a banned pesticide for aquaculture products. As a required inspection item, its fast and accurate determination before the products' accessing market is very important. Surface enhanced Raman scattering (SERS) is a promising tool for MG sensing, but it requires the overcoming of several problems such as fairly poor sensitivity and reproducibility, especially laser induced chemical conversion and photo-bleaching during SERS observation. By using a graphene wrapped Ag array based flexible membrane sensor, a modified SERS strategy was proposed for the sensitive and accurate detection of MG. The graphene layer functioned as an inert protector for impeding chemical transferring of the bioproduct Leucomalachite Green (LMG) to MG during the SERS detection, and as a heat transmitter for preventing laser induced photo-bleaching, which enables the separate detection of MG and LMG in fish extracts. The combination of the Ag array and the graphene cover also produced plentiful densely and uniformly distributed hot spots, leading to analytical enhancement factor up to 3.9 × 10 8 and excellent reproducibility (relative standard deviation low to 5.8% for 70 runs). The proposed method was easily used for MG detection with limit of detection (LOD) as low as 2.7 × 10 -11  mol L -1 . The flexibility of the sensor enable it have a merit for in-field fast detection of MG residues on the scale of a living fish through a surface extraction and paste transferring manner. The developed strategy was successfully applied in the analysis of real samples, showing good prospects for both the fast inspection and quantitative detection of MG. Copyright © 2018 Elsevier B.V. All rights reserved.

OpenTopography: Addressing Big Data Challenges Using Cloud Computing, HPC, and Data Analytics

NASA Astrophysics Data System (ADS)

Crosby, C. J.; Nandigam, V.; Phan, M.; Youn, C.; Baru, C.; Arrowsmith, R.

2014-12-01

OpenTopography (OT) is a geoinformatics-based data facility initiated in 2009 for democratizing access to high-resolution topographic data, derived products, and tools. Hosted at the San Diego Supercomputer Center (SDSC), OT utilizes cyberinfrastructure, including large-scale data management, high-performance computing, and service-oriented architectures to provide efficient Web based access to large, high-resolution topographic datasets. OT collocates data with processing tools to enable users to quickly access custom data and derived products for their application. OT's ongoing R&D efforts aim to solve emerging technical challenges associated with exponential growth in data, higher order data products, as well as user base. Optimization of data management strategies can be informed by a comprehensive set of OT user access metrics that allows us to better understand usage patterns with respect to the data. By analyzing the spatiotemporal access patterns within the datasets, we can map areas of the data archive that are highly active (hot) versus the ones that are rarely accessed (cold). This enables us to architect a tiered storage environment consisting of high performance disk storage (SSD) for the hot areas and less expensive slower disk for the cold ones, thereby optimizing price to performance. From a compute perspective, OT is looking at cloud based solutions such as the Microsoft Azure platform to handle sudden increases in load. An OT virtual machine image in Microsoft's VM Depot can be invoked and deployed quickly in response to increased system demand. OT has also integrated SDSC HPC systems like the Gordon supercomputer into our infrastructure tier to enable compute intensive workloads like parallel computation of hydrologic routing on high resolution topography. This capability also allows OT to scale to HPC resources during high loads to meet user demand and provide more efficient processing. With a growing user base and maturing scientific user community comes new requests for algorithms and processing capabilities. To address this demand, OT is developing an extensible service based architecture for integrating community-developed software. This "plugable" approach to Web service deployment will enable new processing and analysis tools to run collocated with OT hosted data.

Army Communicator. Volume 37, Number 2, Summer 2012

DTIC Science & Technology

2012-01-01

solution will have to meet four criteria: FIPS 140-2 validated crypto; approved data-at-rest; Common Access Card enablement; and, enterprise management...Information Grid. Common Access Cards , Federal Information Processing Standard 140-2 certifications, and software compliance are just a few of the...and Evaluation Command BMC – Brigade Modernization Command CAC – Common Access Card FIPS – Federal Information Processing Standard GIG – Global

Ubiquitous Accessibility for People with Visual Impairments: Are We There Yet?

PubMed

Billah, Syed Masum; Ashok, Vikas; Porter, Donald E; Ramakrishnan, I V

2017-05-01

Ubiquitous access is an increasingly common vision of computing, wherein users can interact with any computing device or service from anywhere, at any time. In the era of personal computing, users with visual impairments required special-purpose, assistive technologies, such as screen readers, to interact with computers. This paper investigates whether technologies like screen readers have kept pace with, or have created a barrier to, the trend toward ubiquitous access, with a specific focus on desktop computing as this is still the primary way computers are used in education and employment. Towards that, the paper presents a user study with 21 visually-impaired participants, specifically involving the switching of screen readers within and across different computing platforms, and the use of screen readers in remote access scenarios. Among the findings, the study shows that, even for remote desktop access-an early forerunner of true ubiquitous access-screen readers are too limited, if not unusable. The study also identifies several accessibility needs, such as uniformity of navigational experience across devices, and recommends potential solutions. In summary, assistive technologies have not made the jump into the era of ubiquitous access, and multiple, inconsistent screen readers create new practical problems for users with visual impairments.

SAFE: SPARQL Federation over RDF Data Cubes with Access Control.

PubMed

Khan, Yasar; Saleem, Muhammad; Mehdi, Muntazir; Hogan, Aidan; Mehmood, Qaiser; Rebholz-Schuhmann, Dietrich; Sahay, Ratnesh

2017-02-01

Several query federation engines have been proposed for accessing public Linked Open Data sources. However, in many domains, resources are sensitive and access to these resources is tightly controlled by stakeholders; consequently, privacy is a major concern when federating queries over such datasets. In the Healthcare and Life Sciences (HCLS) domain real-world datasets contain sensitive statistical information: strict ownership is granted to individuals working in hospitals, research labs, clinical trial organisers, etc. Therefore, the legal and ethical concerns on (i) preserving the anonymity of patients (or clinical subjects); and (ii) respecting data ownership through access control; are key challenges faced by the data analytics community working within the HCLS domain. Likewise statistical data play a key role in the domain, where the RDF Data Cube Vocabulary has been proposed as a standard format to enable the exchange of such data. However, to the best of our knowledge, no existing approach has looked to optimise federated queries over such statistical data. We present SAFE: a query federation engine that enables policy-aware access to sensitive statistical datasets represented as RDF data cubes. SAFE is designed specifically to query statistical RDF data cubes in a distributed setting, where access control is coupled with source selection, user profiles and their access rights. SAFE proposes a join-aware source selection method that avoids wasteful requests to irrelevant and unauthorised data sources. In order to preserve anonymity and enforce stricter access control, SAFE's indexing system does not hold any data instances-it stores only predicates and endpoints. The resulting data summary has a significantly lower index generation time and size compared to existing engines, which allows for faster updates when sources change. We validate the performance of the system with experiments over real-world datasets provided by three clinical organisations as well as legacy linked datasets. We show that SAFE enables granular graph-level access control over distributed clinical RDF data cubes and efficiently reduces the source selection and overall query execution time when compared with general-purpose SPARQL query federation engines in the targeted setting.

The Virtual Solar Observatory: What Are We Up To Now?

NASA Technical Reports Server (NTRS)

Gurman, J. B.; Hill, F.; Suarez-Sola, F.; Bogart, R.; Amezcua, A.; Martens, P.; Hourcle, J.; Hughitt, K.; Davey, A.

2012-01-01

In the nearly ten years of a functional Virtual Solar Observatory (VSO), http://virtualsolar.org/ we have made it possible to query and access sixty-seven distinct solar data products and several event lists from nine spacecraft and fifteen observatories or observing networks. We have used existing VSO technology, and developed new software, for a distributed network of sites caching and serving SDO HMI and/ or AlA data. We have also developed an application programming interface (API) that has enabled VSO search and data access capabilities in IDL, Python, and Java. We also have quite a bit of work yet to do, including completion of the implementation of access to SDO EVE data, and access to some nineteen other data sets from space- and ground-based observatories. In addition, we have been developing a new graphic user interface that will enable the saving of user interface and search preferences. We solicit advice from the community input prioritizing our task list, and adding to it

Performance Analysis of Direct-Sequence Code-Division Multiple-Access Communications with Asymmetric Quadrature Phase-Shift-Keying Modulation

NASA Technical Reports Server (NTRS)

Wang, C.-W.; Stark, W.

2005-01-01

This article considers a quaternary direct-sequence code-division multiple-access (DS-CDMA) communication system with asymmetric quadrature phase-shift-keying (AQPSK) modulation for unequal error protection (UEP) capability. Both time synchronous and asynchronous cases are investigated. An expression for the probability distribution of the multiple-access interference is derived. The exact bit-error performance and the approximate performance using a Gaussian approximation and random signature sequences are evaluated by extending the techniques used for uniform quadrature phase-shift-keying (QPSK) and binary phase-shift-keying (BPSK) DS-CDMA systems. Finally, a general system model with unequal user power and the near-far problem is considered and analyzed. The results show that, for a system with UEP capability, the less protected data bits are more sensitive to the near-far effect that occurs in a multiple-access environment than are the more protected bits.

Magnetizable stent-grafts enable endothelial cell capture

NASA Astrophysics Data System (ADS)

Tefft, Brandon J.; Uthamaraj, Susheil; Harburn, J. Jonathan; Hlinomaz, Ota; Lerman, Amir; Dragomir-Daescu, Dan; Sandhu, Gurpreet S.

2017-04-01

Emerging nanotechnologies have enabled the use of magnetic forces to guide the movement of magnetically-labeled cells, drugs, and other therapeutic agents. Endothelial cells labeled with superparamagnetic iron oxide nanoparticles (SPION) have previously been captured on the surface of magnetizable 2205 duplex stainless steel stents in a porcine coronary implantation model. Recently, we have coated these stents with electrospun polyurethane nanofibers to fabricate prototype stent-grafts. Facilitated endothelialization may help improve the healing of arteries treated with stent-grafts, reduce the risk of thrombosis and restenosis, and enable small-caliber applications. When placed in a SPION-labeled endothelial cell suspension in the presence of an external magnetic field, magnetized stent-grafts successfully captured cells to the surface regions adjacent to the stent struts. Implantation within the coronary circulation of pigs (n=13) followed immediately by SPION-labeled autologous endothelial cell delivery resulted in widely patent devices with a thin, uniform neointima and no signs of thrombosis or inflammation at 7 days. Furthermore, the magnetized stent-grafts successfully captured and retained SPION-labeled endothelial cells to select regions adjacent to stent struts and between stent struts, whereas the non-magnetized control stent-grafts did not. Early results with these prototype devices are encouraging and further refinements will be necessary in order to achieve more uniform cell capture and complete endothelialization. Once optimized, this approach may lead to more rapid and complete healing of vascular stent-grafts with a concomitant improvement in long-term device performance.

Magnetizable stent-grafts enable endothelial cell capture.

PubMed

Tefft, Brandon J; Uthamaraj, Susheil; Harburn, J Jonathan; Hlinomaz, Ota; Lerman, Amir; Dragomir-Daescu, Dan; Sandhu, Gurpreet S

2017-04-01

Emerging nanotechnologies have enabled the use of magnetic forces to guide the movement of magnetically-labeled cells, drugs, and other therapeutic agents. Endothelial cells labeled with superparamagnetic iron oxide nanoparticles (SPION) have previously been captured on the surface of magnetizable 2205 duplex stainless steel stents in a porcine coronary implantation model. Recently, we have coated these stents with electrospun polyurethane nanofibers to fabricate prototype stent-grafts. Facilitated endothelialization may help improve the healing of arteries treated with stent-grafts, reduce the risk of thrombosis and restenosis, and enable small-caliber applications. When placed in a SPION-labeled endothelial cell suspension in the presence of an external magnetic field, magnetized stent-grafts successfully captured cells to the surface regions adjacent to the stent struts. Implantation within the coronary circulation of pigs (n=13) followed immediately by SPION-labeled autologous endothelial cell delivery resulted in widely patent devices with a thin, uniform neointima and no signs of thrombosis or inflammation at 7 days. Furthermore, the magnetized stent-grafts successfully captured and retained SPION-labeled endothelial cells to select regions adjacent to stent struts and between stent struts, whereas the non-magnetized control stent-grafts did not. Early results with these prototype devices are encouraging and further refinements will be necessary in order to achieve more uniform cell capture and complete endothelialization. Once optimized, this approach may lead to more rapid and complete healing of vascular stent-grafts with a concomitant improvement in long-term device performance.

Teaching Mathematics in Primary Schools with Challenging Tasks: The Big (Not So) Friendly Giant

ERIC Educational Resources Information Center

Russo, James

2016-01-01

The use of enabling and extending prompts allows tasks to be both accessible and challenging within a classroom. This article provides an example of how to use enabling and extending prompts effectively when employing a challenging task in Year 2.

Probing Motion of Fast Radio Burst Sources by Timing Strongly Lensed Repeaters

NASA Astrophysics Data System (ADS)

Dai, Liang; Lu, Wenbin

2017-09-01

Given the possible repetitive nature of fast radio bursts (FRBs), their cosmological origin, and their high occurrence, detection of strongly lensed sources due to intervening galaxy lenses is possible with forthcoming radio surveys. We show that if multiple images of a repeating source are resolved with VLBI, using a method independent of lens modeling, accurate timing could reveal non-uniform motion, either physical or apparent, of the emission spot. This can probe the physical nature of FRBs and their surrounding environments, constraining scenarios including orbital motion around a stellar companion if FRBs require a compact star in a special system, and jet-medium interactions for which the location of the emission spot may randomly vary. The high timing precision possible for FRBs (˜ms) compared with the typical time delays between images in galaxy lensing (≳10 days) enables the measurement of tiny fractional changes in the delays (˜ {10}-9) and hence the detection of time-delay variations induced by relative motions between the source, the lens, and the Earth. We show that uniform cosmic peculiar velocities only cause the delay time to drift linearly, and that the effect from the Earth’s orbital motion can be accurately subtracted, thus enabling a search for non-trivial source motion. For a timing accuracy of ˜1 ms and a repetition rate (of detected bursts) of ˜0.05 per day of a single FRB source, non-uniform displacement ≳0.1-1 au of the emission spot perpendicular to the line of sight is detectable if repetitions are seen over a period of hundreds of days.

E-learning for healthcare students: developing the communities of practice framework.

PubMed

Moule, Pam

2006-05-01

This paper presents research considering whether healthcare students were able to develop characteristics of communities of practice when engaged in an online module. Little is known about whether the communities of practice framework can be applied to online learning, with no previous consideration of its potential use within healthcare education. Using a case study approach the research, completed in 2004, had two phases. A questionnaire was administered to a group of 109 healthcare students to gain information on which to base sampling for the subsequent phase. Phase 2 employed three strands of data collection: five students completed an online diary, the online interactions of seven students were captured on a discussion board and three students were interviewed. Data were analysed using a form of pattern matching. Students were able to develop essential elements of communities of practice: mutual engagement, joint enterprise and shared repertoire, though this was not uniformly seen. Particular issues emerged for the online community, including enabling access to the online environment to support mutual engagement. The development of trust was also threatened by difficulties of presenting identities online. Joint enterprise was hampered by the online situation, although the virtual classroom proved essential for supporting endeavour. Not all students were committed to their groups. There was some evidence of group members developing shared repertoire, as routines of group working emerged. Professional understanding and computer skills were also enhanced. The framework can be applied to supporting online learning internationally amongst students and has applicability to professional groups. Those intending to employ the framework should ensure that students can gain access to the community and have the computer skills to engage. Course design should be considered to ensure support for developing the essential components of communities of practice.

Nuclear Energy for Space Exploration

NASA Technical Reports Server (NTRS)

Houts, Michael G.

2010-01-01

Nuclear power and propulsion systems can enable exciting space exploration missions. These include bases on the moon and Mars; and the exploration, development, and utilization of the solar system. In the near-term, fission surface power systems could provide abundant, constant, cost-effective power anywhere on the surface of the Moon or Mars, independent of available sunlight. Affordable access to Mars, the asteroid belt, or other destinations could be provided by nuclear thermal rockets. In the further term, high performance fission power supplies could enable both extremely high power levels on planetary surfaces and fission electric propulsion vehicles for rapid, efficient cargo and crew transfer. Advanced fission propulsion systems could eventually allow routine access to the entire solar system. Fission systems could also enable the utilization of resources within the solar system. Fusion and antimatter systems may also be viable in the future

Ranking and clustering of nodes in networks with smart teleportation

NASA Astrophysics Data System (ADS)

Lambiotte, R.; Rosvall, M.

2012-05-01

Random teleportation is a necessary evil for ranking and clustering directed networks based on random walks. Teleportation enables ergodic solutions, but the solutions must necessarily depend on the exact implementation and parametrization of the teleportation. For example, in the commonly used PageRank algorithm, the teleportation rate must trade off a heavily biased solution with a uniform solution. Here we show that teleportation to links rather than nodes enables a much smoother trade-off and effectively more robust results. We also show that, by not recording the teleportation steps of the random walker, we can further reduce the effect of teleportation with dramatic effects on clustering.

Compact light-emitting diode lighting ring for video-assisted thoracic surgery.

PubMed

Lu, Ming-Kuan; Chang, Feng-Chen; Wang, Wen-Zhe; Hsieh, Chih-Cheng; Kao, Fu-Jen

2014-01-01

In this work, a foldable ring-shaped light-emitting diode (LED) lighting assembly, designed to attach to a rubber wound retractor, is realized and tested through porcine animal experiments. Enabled by the small size and the high efficiency of LED chips, the lighting assembly is compact, flexible, and disposable while providing direct and high brightness lighting for more uniform background illumination in video-assisted thoracic surgery (VATS). When compared with a conventional fiber bundle coupled light source that is usually used in laparoscopy and endoscopy, the much broader solid angle of illumination enabled by the LED assembly allows greatly improved background lighting and imaging quality in VATS.

Heat treatment furnace

DOEpatents

Seals, Roland D; Parrott, Jeffrey G; DeMint, Paul D; Finney, Kevin R; Blue, Charles T

2014-10-21

A furnace heats through both infrared radiation and convective air utilizing an infrared/purge gas design that enables improved temperature control to enable more uniform treatment of workpieces. The furnace utilizes lamps, the electrical end connections of which are located in an enclosure outside the furnace chamber, with the lamps extending into the furnace chamber through openings in the wall of the chamber. The enclosure is purged with gas, which gas flows from the enclosure into the furnace chamber via the openings in the wall of the chamber so that the gas flows above and around the lamps and is heated to form a convective mechanism in heating parts.

Templated assembly of Co-Pt nanoparticles via thermal and laser-induced dewetting of bilayer metal films.

PubMed

Oh, Yong-Jun; Kim, Jung-Hwan; Thompson, Carl V; Ross, Caroline A

2013-01-07

Templated dewetting of a Co/Pt metal bilayer film on a topographic substrate was used to assemble arrays of Co-Pt alloy nanoparticles, with highly uniform particle size, shape and notably composition compared to nanoparticles formed on an untemplated substrate. Solid-state and liquid-state dewetting processes, using furnace annealing and laser irradiation respectively, were compared. Liquid state dewetting produced more uniform, conformal nanoparticles but they had a polycrystalline disordered fcc structure and relatively low magnetic coercivity. In contrast, solid state dewetting enabled formation of magnetically hard, ordered L1(0) Co-Pt single-crystal particles with coercivity >12 kOe. Furnace annealing converted the nanoparticles formed by liquid state dewetting into the L1(0) phase.

Multi-oxide active layer deposition using Applied Materials Pivot array coater for high-mobility metal oxide TFT

NASA Astrophysics Data System (ADS)

Park, Hyun Chan; Scheer, Evelyn; Witting, Karin; Hanika, Markus; Bender, Marcus; Hsu, Hao Chien; Yim, Dong Kil

2015-11-01

By controlling a thin indium tin oxide (ITO), indium zinc oxide interface layer between gate insulator and indium gallium zinc oxide (IGZO), the thin-film transistor (TFT) performance can reach higher mobility as conventional IGZO as well as superior stability. For large-area display application, Applied Materials static PVD array coater (Applied Materials GmbH & Co. KG, Alzenau, Germany) using rotary targets has been developed to enable uniform thin layer deposition in display industry. Unique magnet motion parameter optimization in Pivot sputtering coater is shown to provide very uniform thin ITO layer to reach TFT performance with high mobility, not only on small scale, but also on Gen8.5 (2500 × 2200 mm glass size) production system.

Alternative Shapes and Shaping Techniques for Enhanced Transformer Ratios in Beam Driven Techniques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lemery, F.; Piot, P.

The transformer ration of collinear beam-driven techniques can be significantly improved by shaping the current profile of the drive bunch. To date, several current shapes have been proposed to increase the transformer ratio and produce quasi-uniform energy loss within the drive bunch. Some of these tailoring techniques are possible as a results of recent beam-dynamics advances, e.g., transverse-to-longitudinal emittance exchanger. In ths paper, we propose an alternative class of longitudinal shapes that enable high transformer ratio and uniform energy loss across the drive bunch. We also suggest a simple method based on photocathode-laser shaping and passive shaping in wakefield structuremore » to realize shape close to the theoretically optimized current profiles.« less

Effects of Mild-to-Moderate Ambient Cold and Chemical Protective Clothing (MOPP-IV) on Cognitive Performance of Male and Female Soldiers

DTIC Science & Technology

1990-07-01

heat stress. The ambient temperature for this condition (12.8 C) was determined by calculating its thermal comfort equivalence with another control...condition in which only the Battle Dress Uniform (BDU) was worn (21.1 C). The matching of the two conditions for thermal comfort enables differences

Hybrid Physical Vapor Deposition Instrument for Advanced Functional Multilayers and Materials

DTIC Science & Technology

2016-04-27

Hybrid Physical Vapor Deposition Instrument for Advanced Functional Multilayers and Materials PI Maria received support to construct a physical...vapor deposition (PVD) system that combines electron beam (e- beam) evaporation, magnetron sputtering, pulsed laser ablation, and ion-assisted deposition ...The instrumentation enables clean, uniform, and rapid deposition of a wide variety of metallic, semiconducting, and ceramic thin films with

The spectral method and the central limit theorem for general Markov chains

NASA Astrophysics Data System (ADS)

Nagaev, S. V.

2017-12-01

We consider Markov chains with an arbitrary phase space and develop a modification of the spectral method that enables us to prove the central limit theorem (CLT) for non-uniformly ergodic Markov chains. The conditions imposed on the transition function are more general than those by Athreya-Ney and Nummelin. Our proof of the CLT is purely analytical.

1998 Army Modernization Plan

DTIC Science & Technology

1998-01-01

Biological (CB) Protective Duty Uniform (STO) • Biometrics (SRO) • Nanoscience (SRO) • Millimeter Wave Material and Dissemination Technology... Biometrics and Nanoscience SROs will enable the development of advanced NBC detection and characterization systems, including the exploitation of biologically...Requirements Trailers • Procure HEMAT Trailers Figure K-23 K-19 //;<?. U.S. Army 1997Modernization Plan This final fleet assessment, made against the

Social Media, Power, and the Future of VBAC

PubMed Central

Romano, Amy M.; Gerber, Hilary; Andrews, Desirre

2010-01-01

The Internet has been called a disruptive technology because it has shifted power and altered the economics of doing business, whether that business is selling books or providing health care. Social media have accelerated the pace of disruption by enabling interactive information sharing and blurring the lines between the “producers” and “consumers” of knowledge, goods, and services. In the wake of the National Institutes of Health Consensus Development Conference on Vaginal Birth After Cesarean (VBAC) and major national recommendations for maternity care reform, activated, engaged consumers face an unprecedented opportunity to drive meaningful changes in VBAC access and safety. This article examines the role of social networks in informing women about VBAC, producing low-cost, accessible decision aids, and enabling multi-stakeholder collaborations toward workable solutions that remove barriers women face in accessing VBAC. PMID:21170180

Simple video format for mobile applications

NASA Astrophysics Data System (ADS)

Smith, John R.; Miao, Zhourong; Li, Chung-Sheng

2000-04-01

With the advent of pervasive computing, there is a growing demand for enabling multimedia applications on mobile devices. Large numbers of pervasive computing devices, such as personal digital assistants (PDAs), hand-held computer (HHC), smart phones, portable audio players, automotive computing devices, and wearable computers are gaining access to online information sources. However, the pervasive computing devices are often constrained along a number of dimensions, such as processing power, local storage, display size and depth, connectivity, and communication bandwidth, which makes it difficult to access rich image and video content. In this paper, we report on our initial efforts in designing a simple scalable video format with low-decoding and transcoding complexity for pervasive computing. The goal is to enable image and video access for mobile applications such as electronic catalog shopping, video conferencing, remote surveillance and video mail using pervasive computing devices.

Exploring access to care among older people in the last phase of life using the behavioural model of health services use: a qualitative study from the perspective of the next of kin of older persons who had died in a nursing home.

PubMed

Condelius, Anna; Andersson, Magdalena

2015-10-26

There is little investigation into what care older people access during the last phase of their life and what factors enable access to care in this group. Illuminating this from the perspective of the next of kin may provide valuable insights into how the health and social care system operates with reference to providing care for this vulnerable group. The behavioural model of health services use has a wide field of application but has not been tested conceptually regarding access to care from the perspective of the next of kin. The aim of this study was to explore the care accessed by older people during the last phase of their life from the perspective of the next of kin and to conceptually test the behavioural model of health services use. The data collection took place in 2011 by means of qualitative interviews with 14 next of kin of older people who had died in a nursing home. The interviews were analysed using directed content analysis. The behavioural model of health services use was used in deriving the initial coding scheme, including the categories: utilization of health services, consumer satisfaction and characteristics of the population at risk. Utilization of health services in the last phase of life was described in five subcategories named after the type of care accessed i.e. admission to a nursing home, primary healthcare, hospital care, dental care and informal care. The needs were illuminated in the subcategories: general deterioration, medical conditions and acute illness and deterioration when death approaches. Factors that enabled access to care were described in three subcategories: the organisation of care, next of kin and the older person. These factors could also constitute barriers to accessing care. Next of kin's satisfaction with care was illuminated in the subcategories: satisfaction, dissatisfaction and factors influencing satisfaction. One new category was constructed inductively: the situation of the next of kin. A bed in a nursing home was often accessed during what the next of kin regarded as the last phase of life. The needs among older people in the last phase of life can be regarded as complex and worsening over time. Most enabling factors lied within the organisation of care but the next of kin enabled access to care and contributed significantly to care quality. More research is needed regarding ageism and stigmatic attitudes among professionals and informal caregivers acting as a barrier to accessing care for older people in the last phase of their life. The behavioural model of health services use was extended with a new category showing that the situation of the next of kin must be taken into consideration when investigating access to care from their perspective. It may also be appropriate to include informal care as part of the concept of access when investigating access to care among older people in the last phase of their life. The results may not be transferable to older people who have not gained access to a bed in a nursing home or to countries where the healthcare system differs largely from the Swedish.

Naval Research Laboratory Fact Book 2012

DTIC Science & Technology

2012-11-01

Distributed network-based battle management High performance computing supporting uniform and nonuniform memory access with single and multithreaded...hyperspectral systems VNIR, MWIR, and LWIR high-resolution systems Wideband SAR systems RF and laser data links High-speed, high-power...hyperspectral imaging system Long-wave infrared ( LWIR ) quantum well IR photodetector (QWIP) imaging system Research and Development Services Divi- sion

NRL Fact Book

DTIC Science & Technology

2008-01-01

Distributed network-based battle management High performance computing supporting uniform and nonuniform memory access with single and multithreaded...pallet Airborne EO/IR and radar sensors VNIR through SWIR hyperspectral systems VNIR, MWIR, and LWIR high-resolution sys- tems Wideband SAR systems...meteorological sensors Hyperspectral sensor systems (PHILLS) Mid-wave infrared (MWIR) Indium Antimonide (InSb) imaging system Long-wave infrared ( LWIR

Prevent: A Fragmented Counter-Terrorism Strategy

DTIC Science & Technology

2015-05-21

Seminar Leader David M. Wood , COL...David M. Wood for the guidance and support during this process. The learning curve has been steep but worthwhile and your efforts have made the...Mirror Online, “Muslim Worshippers: It’s Madness; Exclusive Army To Scots Cadets: Don’t Wear Uniform near Mosque in Case You Offend,” Muslims, accessed

Expected Annual Emergency Miles per Ambulance: An Indicator for Measuring Availability of Emergency Medical Services Resources

ERIC Educational Resources Information Center

Patterson, P. Daniel; Probst, Janice C.; Moore, Charity G.

2006-01-01

Context: To ensure equitable access to prehospital care, as recommended by the Rural and Frontier Emergency Medical Services (EMS) Agenda for the Future, policymakers will need a uniform measure of EMS infrastructure. Purpose and Methods: This paper proposes a county-level indicator of EMS resource availability that takes into consideration…

Protein and quality analyses of accessions from the USDA soybean germplasm collection for tofu production

USDA-ARS?s Scientific Manuscript database

Food-grade soybeans with large seed size, uniformity, clear hilum, and high 11S/7S ratio are favored by the food industry for making tofu. In order to search for soybean lines with desirable characteristics for making foods, twenty-two soybean lines were selected from the USDA-Soybean Germplasm Coll...

Unlearning and Relearning from Medical Education Research: Teacher Education Research in the Pursuit of Teacher Professionalism

ERIC Educational Resources Information Center

Purinton, Ted

2012-01-01

Educational researchers have increasingly paid attention to how practitioners can access and utilize research knowledge, but the field still has been unable to create a research tradition and corresponding diffusion model that directly and uniformly influences teachers' practice. One reason for this is the contested status of teaching as a…

47 CFR 1.20004 - Maintaining secure and accurate records.

Code of Federal Regulations, 2010 CFR

2010-10-01

... access to call-identifying information, made with or without appropriate authorization, in the form of... that the carrier enables the interception of communications or access to call identifying information; (iii) The identity of the law enforcement officer presenting the authorization; (iv) The name of the...

Enabling Equal Access to Molecular Diagnostics: What Are the Implications for Policy and Health Technology Assessment?

PubMed

Plun-Favreau, Juliette; Immonen-Charalambous, Kaisa; Steuten, Lotte; Strootker, Anja; Rouzier, Roman; Horgan, Denis; Lawler, Mark

2016-01-01

Molecular diagnostics can offer important benefits to patients and are a key enabler of the integration of personalised medicine into health care systems. However, despite their promise, few molecular diagnostics are embedded into clinical practice (especially in Europe) and access to these technologies remains unequal across countries and sometimes even within individual countries. If research translation and the regulatory environments have proven to be more challenging than expected, reimbursement and value assessment remain the main barriers to providing patients with equal access to molecular diagnostics. Unclear or non-existent reimbursement pathways, together with the lack of clear evidence requirements, have led to significant delays in the assessment of molecular diagnostics technologies in certain countries. Additionally, the lack of dedicated diagnostics budgets and the siloed nature of resource allocation within certain health care systems have significantly delayed diagnostics commissioning. This article will consider the perspectives of different stakeholders (patients, health care payers, health care professionals, and manufacturers) on the provision of a research-enabled, patient-focused molecular diagnostics platform that supports optimal patient care. Through the discussion of specific case studies, and building on the experience from countries that have successfully integrated molecular diagnostics into clinical practice, this article will discuss the necessary evolutions in policy and health technology assessment to ensure that patients can have equal access to appropriate molecular diagnostics. © 2016 S. Karger AG, Basel.

Structuring Legacy Pathology Reports by openEHR Archetypes to Enable Semantic Querying.

PubMed

Kropf, Stefan; Krücken, Peter; Mueller, Wolf; Denecke, Kerstin

2017-05-18

Clinical information is often stored as free text, e.g. in discharge summaries or pathology reports. These documents are semi-structured using section headers, numbered lists, items and classification strings. However, it is still challenging to retrieve relevant documents since keyword searches applied on complete unstructured documents result in many false positive retrieval results. We are concentrating on the processing of pathology reports as an example for unstructured clinical documents. The objective is to transform reports semi-automatically into an information structure that enables an improved access and retrieval of relevant data. The data is expected to be stored in a standardized, structured way to make it accessible for queries that are applied to specific sections of a document (section-sensitive queries) and for information reuse. Our processing pipeline comprises information modelling, section boundary detection and section-sensitive queries. For enabling a focused search in unstructured data, documents are automatically structured and transformed into a patient information model specified through openEHR archetypes. The resulting XML-based pathology electronic health records (PEHRs) are queried by XQuery and visualized by XSLT in HTML. Pathology reports (PRs) can be reliably structured into sections by a keyword-based approach. The information modelling using openEHR allows saving time in the modelling process since many archetypes can be reused. The resulting standardized, structured PEHRs allow accessing relevant data by retrieving data matching user queries. Mapping unstructured reports into a standardized information model is a practical solution for a better access to data. Archetype-based XML enables section-sensitive retrieval and visualisation by well-established XML techniques. Focussing the retrieval to particular sections has the potential of saving retrieval time and improving the accuracy of the retrieval.

Barriers and enablers for iron folic acid (IFA) supplementation in pregnant women.

PubMed

Siekmans, Kendra; Roche, Marion; Kung'u, Jacqueline K; Desrochers, Rachelle E; De-Regil, Luz Maria

2017-12-22

In order to inform large scale supplementation programme design, we review and summarize the barriers and enablers for improved coverage and utilization of iron and folic acid (IFA) supplements by pregnant women in 7 countries in Africa and Asia. Mixed methods were used to analyse IFA supplementation programmes in Afghanistan, Bangladesh, Indonesia, Ethiopia, Kenya, Nigeria, and Senegal based on formative research conducted in 2012-2013. Qualitative data from focus-group discussions and interviews with women and service providers were used for content analysis to elicit common themes on barriers and enablers at internal, external, and relational levels. Anaemia symptoms in pregnancy are well known among women and health care providers in all countries, yet many women do not feel personally at risk. Broad awareness and increased coverage of facility-based antenatal care (ANC) make it an efficient delivery channel for IFA; however, first trimester access to IFA is hindered by beliefs about when to first attend ANC and preferences for disclosing pregnancy status. Variable access and poor quality ANC services, including insufficient IFA supplies and inadequate counselling to encourage consumption, are barriers to both coverage and adherence. Community-based delivery of IFA and referral to ANC provides earlier and more frequent access and opportunities for follow-up. Improving ANC access and quality is needed to facilitate IFA supplementation during pregnancy. Community-based delivery and counselling can address problems of timely and continuous access to supplements. Renewed investment in training for service providers and effective behaviour change designs are urgently needed to achieve the desired impact. © 2018 John Wiley & Sons Ltd.

Critical behavior of subcellular density organization during neutrophil activation and migration.

PubMed

Baker-Groberg, Sandra M; Phillips, Kevin G; Healy, Laura D; Itakura, Asako; Porter, Juliana E; Newton, Paul K; Nan, Xiaolin; McCarty, Owen J T

2015-12-01

Physical theories of active matter continue to provide a quantitative understanding of dynamic cellular phenomena, including cell locomotion. Although various investigations of the rheology of cells have identified important viscoelastic and traction force parameters for use in these theoretical approaches, a key variable has remained elusive both in theoretical and experimental approaches: the spatiotemporal behavior of the subcellular density. The evolution of the subcellular density has been qualitatively observed for decades as it provides the source of image contrast in label-free imaging modalities (e.g., differential interference contrast, phase contrast) used to investigate cellular specimens. While these modalities directly visualize cell structure, they do not provide quantitative access to the structures being visualized. We present an established quantitative imaging approach, non-interferometric quantitative phase microscopy, to elucidate the subcellular density dynamics in neutrophils undergoing chemokinesis following uniform bacterial peptide stimulation. Through this approach, we identify a power law dependence of the neutrophil mean density on time with a critical point, suggesting a critical density is required for motility on 2D substrates. Next we elucidate a continuum law relating mean cell density, area, and total mass that is conserved during neutrophil polarization and migration. Together, our approach and quantitative findings will enable investigators to define the physics coupling cytoskeletal dynamics with subcellular density dynamics during cell migration.

Critical behavior of subcellular density organization during neutrophil activation and migration

PubMed Central

Baker-Groberg, Sandra M.; Phillips, Kevin G.; Healy, Laura D.; Itakura, Asako; Porter, Juliana E.; Newton, Paul K.; Nan, Xiaolin; McCarty, Owen J.T.

2015-01-01

Physical theories of active matter continue to provide a quantitative understanding of dynamic cellular phenomena, including cell locomotion. Although various investigations of the rheology of cells have identified important viscoelastic and traction force parameters for use in these theoretical approaches, a key variable has remained elusive both in theoretical and experimental approaches: the spatiotemporal behavior of the subcellular density. The evolution of the subcellular density has been qualitatively observed for decades as it provides the source of image contrast in label-free imaging modalities (e.g., differential interference contrast, phase contrast) used to investigate cellular specimens. While these modalities directly visualize cell structure, they do not provide quantitative access to the structures being visualized. We present an established quantitative imaging approach, non-interferometric quantitative phase microscopy, to elucidate the subcellular density dynamics in neutrophils undergoing chemokinesis following uniform bacterial peptide stimulation. Through this approach, we identify a power law dependence of the neutrophil mean density on time with a critical point, suggesting a critical density is required for motility on 2D substrates. Next we elucidate a continuum law relating mean cell density, area, and total mass that is conserved during neutrophil polarization and migration. Together, our approach and quantitative findings will enable investigators to define the physics coupling cytoskeletal dynamics with subcellular density dynamics during cell migration. PMID:26640599

Plasma-Jet-Driven Magneto-Inertial Fusion (PJMIF): Physics and Design for a Plasma Liner Formation Experiment

NASA Astrophysics Data System (ADS)

Hsu, Scott; Cassibry, Jason; Witherspoon, F. Douglas

2014-10-01

Spherically imploding plasma liners are a potential standoff compression driver for magneto-inertial fusion, which is a hybrid of and operates in an intermediate density between those of magnetic and inertial fusion. We propose to use an array of merging supersonic plasma jets to form a spherically imploding plasma liner. The jets are to be formed by pulsed coaxial guns with contoured electrodes that are placed sufficiently far from the location of target compression such that no hardware is repetitively destroyed. As such, the repetition rate can be higher (e.g., 1 Hz) and ultimately the power-plant economics can be more attractive than most other MIF approaches. During the R&D phase, a high experimental shot rate at reasonably low cost (e.g., < 1 k/shot) may be achieved with excellent diagnostic access, thus enabling a rapid learning rate. After some background on PJMIF and its prospects for reactor-relevant energy gain, this poster describes the physics objectives and design of a proposed 60-gun plasma-liner-formation experiment, which will provide experimental data on: (i) scaling of peak liner ram pressure versus initial jet parameters, (ii) liner non-uniformity characterization and control, and (iii) control of liner profiles for eventual gain optimization.

Recombinant Spider Silk Functionalized with a Motif from Fibronectin Mediates Cell Adhesion and Growth on Polymeric Substrates by Entrapping Cells During Self-Assembly.

PubMed

Tasiopoulos, Christos Panagiotis; Widhe, Mona; Hedhammar, My

2018-05-02

In vitro endothelialization of synthetic grafts or engineered vascular constructs is considered a promising alternative to overcome shortcomings in the availability of autologous vessels and in-graft complications with synthetics. A number of cell-seeding techniques have been implemented to render vascular grafts accessible for cells to attach, proliferate, and spread over the surface area. Nonetheless, seeding efficiency and the time needed for cells to adhere varies dramatically. Herein, we investigated a novel cell-seeding approach (denoted co-seeding) that enables cells to bind to a motif from fibronectin included in a recombinant spider silk protein. Entrapment of cells occurs at the same time as the silk assembles into a nanofibrillar coating on various substrates. Cell adhesion analysis showed that the technique can markedly improve cell-seeding efficiency to nonfunctionalized polystyrene surfaces, as well as establish cell attachment and growth of human dermal microvascular endothelial cells on bare polyethylene terephthalate and polytetrafluoroethylene (PTFE) substrates. Scanning electron microscopy images revealed a uniform endothelial cell layer and cell-substratum compliance with the functionalized silk protein to PTFE surfaces. The co-seeding technique holds a great promise as a method to reliably and quickly cellularize engineered vascular constructs as well as to in vitro endothelialize commercially available cardiovascular grafts.

Energy research with neutrons (ErwiN) and installation of a fast neutron powder diffraction option at the MLZ, Germany1

PubMed Central

Mühlbauer, Martin J.

2018-01-01

The need for rapid data collection and studies of small sample volumes in the range of cubic millimetres are the main driving forces for the concept of a new high-throughput monochromatic diffraction instrument at the Heinz Maier-Leibnitz Zentrum (MLZ), Germany. A large region of reciprocal space will be accessed by a detector with sufficient dynamic range and microsecond time resolution, while allowing for a variety of complementary sample environments. The medium-resolution neutron powder diffraction option for ‘energy research with neutrons’ (ErwiN) at the high-flux FRM II neutron source at the MLZ is foreseen to meet future demand. ErwiN will address studies of energy-related systems and materials with respect to their structure and uniformity by means of bulk and spatially resolved neutron powder diffraction. A set of experimental options will be implemented, enabling time-resolved studies, rapid parametric measurements as a function of external parameters and studies of small samples using an adapted radial collimator. The proposed powder diffraction option ErwiN will bridge the gap in functionality between the high-resolution powder diffractometer SPODI and the time-of-flight diffractometers POWTEX and SAPHiR at the MLZ. PMID:29896055

Direct electrical control of IgG conformation and functional activity at surfaces

NASA Astrophysics Data System (ADS)

Ghisellini, Paola; Caiazzo, Marialuisa; Alessandrini, Andrea; Eggenhöffner, Roberto; Vassalli, Massimo; Facci, Paolo

2016-11-01

We have devised a supramolecular edifice involving His-tagged protein A and antibodies to yield surface immobilized, uniformly oriented, IgG-type, antibody layers with Fab fragments exposed off an electrode surface. We demonstrate here that we can affect the conformation of IgGs, likely pushing/pulling electrostatically Fab fragments towards/from the electrode surface. A potential difference between electrode and solution acts on IgGs’ charged aminoacids modulating the accessibility of the specific recognition regions of Fab fragments by antigens in solution. Consequently, antibody-antigen affinity is affected by the sign of the applied potential: a positive potential enables an effective capture of antigens; a negative one pulls the fragments towards the electrode, where steric hindrance caused by neighboring molecules largely hampers the capture of antigens. Different experimental techniques (electrochemical quartz crystal microbalance, electrochemical impedance spectroscopy, fluorescence confocal microscopy and electrochemical atomic force spectroscopy) were used to evaluate binding kinetics, surface coverage, effect of the applied electric field on IgGs, and role of charged residues on the phenomenon described. These findings expand the concept of electrical control of biological reactions and can be used to gate electrically specific recognition reactions with impact in biosensors, bioactuators, smart biodevices, nanomedicine, and fundamental studies related to chemical reaction kinetics.

Improved interface control for high-performance graphene-based organic solar cells

NASA Astrophysics Data System (ADS)

Jung, Seungon; Lee, Junghyun; Choi, Yunseong; Myeon Lee, Sang; Yang, Changduk; Park, Hyesung

2017-12-01

The demand for high-efficiency flexible optoelectronic devices is ever-increasing because next-generation electronic devices that comprise portable or wearable electronic systems are set to play an important role. Graphene has received extensive attention as it is considered to be a promising candidate material for transparent flexible electrode platforms owing to its outstanding electrical, optical, and physical properties. Despite these properties, the inert and hydrophobic nature of graphene surfaces renders it difficult to use in optoelectronic devices. In particular, commonly used charge transporting layer (CTL) materials for organic solar cells (OSCs) cannot uniformly coat a graphene surface, which leads to such devices failing. Herein, this paper proposes an approach that will enable CTL materials to completely cover a graphene electrode; this is done with the assistance of commonly accessible polar solvents. These are successfully applied to various configurations of OSCs, with power conversion efficiencies of 8.17% for graphene electrode-based c-OSCs (OSCs with conventional structures), 8.38% for i-OSCs (OSCs with inverted structures), and 7.53% for flexible solar cells. The proposed approach is expected to bring about significant advances for efficiency enhancements in graphene-based optoelectronic devices, and it is expected that it will open up new possibilities for flexible optoelectronic systems.

High axial resolution imaging system for large volume tissues using combination of inclined selective plane illumination and mechanical sectioning

PubMed Central

Zhang, Qi; Yang, Xiong; Hu, Qinglei; Bai, Ke; Yin, Fangfang; Li, Ning; Gang, Yadong; Wang, Xiaojun; Zeng, Shaoqun

2017-01-01

To resolve fine structures of biological systems like neurons, it is required to realize microscopic imaging with sufficient spatial resolution in three dimensional systems. With regular optical imaging systems, high lateral resolution is accessible while high axial resolution is hard to achieve in a large volume. We introduce an imaging system for high 3D resolution fluorescence imaging of large volume tissues. Selective plane illumination was adopted to provide high axial resolution. A scientific CMOS working in sub-array mode kept the imaging area in the sample surface, which restrained the adverse effect of aberrations caused by inclined illumination. Plastic embedding and precise mechanical sectioning extended the axial range and eliminated distortion during the whole imaging process. The combination of these techniques enabled 3D high resolution imaging of large tissues. Fluorescent bead imaging showed resolutions of 0.59 μm, 0.47μm, and 0.59 μm in the x, y, and z directions, respectively. Data acquired from the volume sample of brain tissue demonstrated the applicability of this imaging system. Imaging of different depths showed uniform performance where details could be recognized in either the near-soma area or terminal area, and fine structures of neurons could be seen in both the xy and xz sections. PMID:29296503

GITEWS, an extensible and open integration platform for manifold sensor systems and processing components based on Sensor Web Enablement and the principles of Service Oriented Architectures

NASA Astrophysics Data System (ADS)

Haener, Rainer; Waechter, Joachim; Fleischer, Jens; Herrnkind, Stefan; Schwarting, Herrmann

2010-05-01

The German Indonesian Tsunami Early Warning System (GITEWS) is a multifaceted system consisting of various sensor types like seismometers, sea level sensors or GPS stations, and processing components, all with their own system behavior and proprietary data structure. To operate a warning chain, beginning from measurements scaling up to warning products, all components have to interact in a correct way, both syntactically and semantically. Designing the system great emphasis was laid on conformity to the Sensor Web Enablement (SWE) specification by the Open Geospatial Consortium (OGC). The technical infrastructure, the so called Tsunami Service Bus (TSB) follows the blueprint of Service Oriented Architectures (SOA). The TSB is an integration concept (SWE) where functionality (observe, task, notify, alert, and process) is grouped around business processes (Monitoring, Decision Support, Sensor Management) and packaged as interoperable services (SAS, SOS, SPS, WNS). The benefits of using a flexible architecture together with SWE lead to an open integration platform: • accessing and controlling heterogeneous sensors in a uniform way (Functional Integration) • assigns functionality to distinct services (Separation of Concerns) • allows resilient relationship between systems (Loose Coupling) • integrates services so that they can be accessed from everywhere (Location Transparency) • enables infrastructures which integrate heterogeneous applications (Encapsulation) • allows combination of services (Orchestration) and data exchange within business processes Warning systems will evolve over time: New sensor types might be added, old sensors will be replaced and processing components will be improved. From a collection of few basic services it shall be possible to compose more complex functionality essential for specific warning systems. Given these requirements a flexible infrastructure is a prerequisite for sustainable systems and their architecture must be tailored for evolution. The use of well-known techniques and widely used open source software implementing industrial standards reduces the impact of service modifications allowing the evolution of a system as a whole. GITEWS implemented a solution to feed sensor raw data from any (remote) system into the infrastructure. Specific dispatchers enable plugging in sensor-type specific processing without changing the architecture. Client components don't need to be adjusted if new sensor-types or individuals are added to the system, because they access them via standardized services. One of the outstanding features of service-oriented architectures is the possibility to compose new services from existing ones. The so called orchestration, allows the definition of new warning processes which can be adapted easily to new requirements. This approach has following advantages: • With implementing SWE it is possible to establish the "detection" and integration of sensors via the internet. Thus a system of systems combining early warning functionality at different levels of detail is feasible. • Any institution could add both its own components as well as components from third parties if they are developed in conformance to SOA principles. In a federation an institution keeps the ownership of its data and decides which data are provided by a service and when. • A system can be deployed at minor costs as a core for own development at any institution and thus enabling autonomous early warning- or monitoring systems. The presentation covers both design and various instantiations (live demonstration) of the GITEWS architecture. Experiences concerning the design and complexity of SWE will be addressed in detail. A substantial amount of attention is laid on the techniques and methods of extending the architecture, adapting proprietary components to SWE services and encoding, and their orchestration in high level workflows and processes. Furthermore the potential of the architecture concerning adaptive behavior, collaboration across boundaries and semantic interoperability will be addressed.

Anatomy Drawing Screencasts: Enabling Flexible Learning for Medical Students

ERIC Educational Resources Information Center

Pickering, James D.

2015-01-01

The traditional lecture remains an essential method of disseminating information to medical students. However, due to the constant development of the modern medical curriculum many institutions are embracing novel means for delivering the core anatomy syllabus. Using mobile media devices is one such way, enabling students to access core material…

75 FR 43825 - Exemption to Prohibition on Circumvention of Copyright Protection Systems for Access Control...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-27

... works such as video games and slide presentations). B. Computer programs that enable wireless telephone... enabling interoperability of such applications, when they have been lawfully obtained, with computer... new printer driver to a computer constitutes a `modification' of the operating system already...

Developing Accessible Cyberinfrastructure-Enabled Knowledge Communities in the National Disability Community: Theory, Practice, and Policy

ERIC Educational Resources Information Center

Myhill, William N.; Cogburn, Derrick L.; Samant, Deepti

2008-01-01

Since publication of the Atkins Commission report 2003, the national scientific community has placed significant emphasis on developing cyberinfrastructure-enabled knowledge communities, which are designed to facilitate enhanced efficiency and collaboration in geographically distributed networks of researchers. This article suggests that the new…

An Architecture for Enabling Migration of Tactical Networks to Future Flexible Ad Hoc WBWF

DTIC Science & Technology

2010-09-01

Requirements Several multiple access schemes TDMA OFDMA SC-OFDMA, FH- CDMA , DS - CDMA , hybrid access schemes, transitions between them Dynamic...parameters algorithms depend on the multiple access scheme If DS - CDMA : handling of macro-diversity (linked to cooperative routing) TDMA and/of OFDMA...Transport format Ciphering @MAC/RLC level : SCM Physical layer (PHY) : signal processing (mod, FEC, etc) CDMA : macro-diversity CDMA , OFDMA

Effects of network node consolidation in optical access and aggregation networks on costs and power consumption

NASA Astrophysics Data System (ADS)

Lange, Christoph; Hülsermann, Ralf; Kosiankowski, Dirk; Geilhardt, Frank; Gladisch, Andreas

2010-01-01

The increasing demand for higher bit rates in access networks requires fiber deployment closer to the subscriber resulting in fiber-to-the-home (FTTH) access networks. Besides higher access bit rates optical access network infrastructure and related technologies enable the network operator to establish larger service areas resulting in a simplified network structure with a lower number of network nodes. By changing the network structure network operators want to benefit from a changed network cost structure by decreasing in short and mid term the upfront investments for network equipment due to concentration effects as well as by reducing the energy costs due to a higher energy efficiency of large network sites housing a high amount of network equipment. In long term also savings in operational expenditures (OpEx) due to the closing of central office (CO) sites are expected. In this paper different architectures for optical access networks basing on state-of-the-art technology are analyzed with respect to network installation costs and power consumption in the context of access node consolidation. Network planning and dimensioning results are calculated for a realistic network scenario of Germany. All node consolidation scenarios are compared against a gigabit capable passive optical network (GPON) based FTTH access network operated from the conventional CO sites. The results show that a moderate reduction of the number of access nodes may be beneficial since in that case the capital expenditures (CapEx) do not rise extraordinarily and savings in OpEx related to the access nodes are expected. The total power consumption does not change significantly with decreasing number of access nodes but clustering effects enable a more energyefficient network operation and optimized power purchase order quantities leading to benefits in energy costs.

Versatile, high-sensitivity faraday cup array for ion implanters

DOEpatents

Musket, Ronald G.; Patterson, Robert G.

2003-01-01

An improved Faraday cup array for determining the dose of ions delivered to a substrate during ion implantation and for monitoring the uniformity of the dose delivered to the substrate. The improved Faraday cup array incorporates a variable size ion beam aperture by changing only an insertable plate that defines the aperture without changing the position of the Faraday cups which are positioned for the operation of the largest ion beam aperture. The design enables the dose sensitivity range, typically 10.sup.11 -10.sup.18 ions/cm.sup.2 to be extended to below 10.sup.6 ions/cm.sup.2. The insertable plate/aperture arrangement is structurally simple and enables scaling to aperture areas between <1 cm.sup.2 and >750 cm.sup.2, and enables ultra-high vacuum (UHV) applications by incorporation of UHV-compatible materials.

Earth Science Data Grid System

NASA Astrophysics Data System (ADS)

Chi, Y.; Yang, R.; Kafatos, M.

2004-05-01

The Earth Science Data Grid System (ESDGS) is a software system in support of earth science data storage and access. It is built upon the Storage Resource Broker (SRB) data grid technology. We have developed a complete data grid system consistent of SRB server providing users uniform access to diverse storage resources in a heterogeneous computing environment and metadata catalog server (MCAT) managing the metadata associated with data set, users, and resources. We also develop the earth science application metadata; geospatial, temporal, and content-based indexing; and some other tools. In this paper, we will describe software architecture and components of the data grid system, and use a practical example in support of storage and access of rainfall data from the Tropical Rainfall Measuring Mission (TRMM) to illustrate its functionality and features.

Mobile computing in critical care.

PubMed

Lapinsky, Stephen E

2007-03-01

Handheld computing devices are increasingly used by health care workers, and offer a mobile platform for point-of-care information access. Improved technology, with larger memory capacity, higher screen resolution, faster processors, and wireless connectivity has broadened the potential roles for these devices in critical care. In addition to the personal information management functions, handheld computers have been used to access reference information, management guidelines and pharmacopoeias as well as to track the educational experience of trainees. They can act as an interface with a clinical information system, providing rapid access to patient information. Despite their popularity, these devices have limitations related to their small size, and acceptance by physicians has not been uniform. In the critical care environment, the risk of transmitting microorganisms by such a portable device should always be considered.

Overview of Sparse Graph for Multiple Access in Future Mobile Networks

NASA Astrophysics Data System (ADS)

Lei, Jing; Li, Baoguo; Li, Erbao; Gong, Zhenghui

2017-10-01

Multiple access via sparse graph, such as low density signature (LDS) and sparse code multiple access (SCMA), is a promising technique for future wireless communications. This survey presents an overview of the developments in this burgeoning field, including transmitter structures, extrinsic information transform (EXIT) chart analysis and comparisons with existing multiple access techniques. Such technique enables multiple access under overloaded conditions to achieve a satisfactory performance. Message passing algorithm is utilized for multi-user detection in the receiver, and structures of the sparse graph are illustrated in detail. Outlooks and challenges of this technique are also presented.

Low-Income Low-Qualified Employees' Access to Workplace Learning

ERIC Educational Resources Information Center

McPherson, Rebecca; Wang, Jia

2014-01-01

Purpose: The purpose of this paper was to investigate the embedded process that enables or constrains low-income low-qualified employees' access to workplace learning in small organizations. Design/methodology/approach: Informed by the sociomaterial approach and cultural historical activity theory, this study adopted a qualitative cross-case study…

A Method for Selection of Appropriate Assistive Technology for Computer Access

ERIC Educational Resources Information Center

Jenko, Mojca

2010-01-01

Assistive technologies (ATs) for computer access enable people with disabilities to be included in the information society. Current methods for assessment and selection of the most appropriate AT for each individual are nonstandardized, lengthy, subjective, and require substantial clinical experience of a multidisciplinary team. This manuscript…

EPAct 2005: A Roadmap for Open Access

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morrison, Jay A.

After nine years of negotiation characterized by significant philosophical swings, Congress came together in the middle to support a moderate vision of open access intended primarily to enable load-serving entities to obtain the transmission service they need to meet the long-term needs of their consumers reliably and economically.

Managing intellectual property to develop medicines for the world's poorest.

PubMed

Fonteilles-Drabek, Sylvie; Reddy, David; Wells, Timothy N C

2017-04-01

It has been argued that patents impede the development and access of medicines for tropical diseases such as malaria. However, we believe that intellectual property can be a key tool to enable timely progression of drug development projects involving multiple partners and to ensure equitable access to successful products.

MaizeGDB: enabling access to basic, translational, and applied research information

USDA-ARS?s Scientific Manuscript database

MaizeGDB is the Maize Genetics and Genomics Database (available online at http://www.maizegdb.org). The MaizeGDB project is not simply an online database and website but rather an information service to maize researchers that supports customized data access and analysis needs to individual research...

The Quality of Urban Environments: Mapping Variation in Access to Community Resources.

ERIC Educational Resources Information Center

Witten, Karen; Exeter, Daniel; Field, Adrian

2003-01-01

Discusses the relationship between community infrastructure and health through the development of the Community Resource Accessibility Index (CRAI) research tool.This area-based index of community services, facilities, and amenities enables comparisons between opportunity structures in the local environment and residents' health and wellbeing. It…

--No Title--

Science.gov Websites

You may be trying to access this site from a secured browser on the server. Please enable scripts and utilizing to make their lives easier and access to information literally at their fingertips. To make information readily available, U. S. Fleet Forces developed mobile applications to provide the

Enabling Accessibility Through Model-Based User Interface Development.

PubMed

Ziegler, Daniel; Peissner, Matthias

2017-01-01

Adaptive user interfaces (AUIs) can increase the accessibility of interactive systems. They provide personalized display and interaction modes to fit individual user needs. Most AUI approaches rely on model-based development, which is considered relatively demanding. This paper explores strategies to make model-based development more attractive for mainstream developers.

Provisional Admission Practices: Blending Access and Support to Facilitate Student Success

ERIC Educational Resources Information Center

Nichols, Andrew Howard; Clinedinst, Melissa

2013-01-01

This report examines provisional admission as an initiative that can expand four-year college access and success for students from economically disadvantaged backgrounds. Provisional admission policies and programs enable students to enroll at an institution under specific conditions. Students are often required to meet certain academic…

NIPTE: a multi-university partnership supporting academic drug development.

PubMed

Gurvich, Vadim J; Byrn, Stephen R

2013-10-01

The strategic goal of academic translational research is to accelerate translational science through the improvement and development of resources for moving discoveries across translational barriers through 'first in humans' studies. To achieve this goal, access to drug discovery resources and preclinical IND-enabling infrastructure is crucial. One potential approach of research institutions for coordinating preclinical development, based on a model from the National Institute for Pharmaceutical Technology and Education (NIPTE), can provide academic translational and medical centers with access to a wide variety of enabling infrastructure for developing small molecule clinical candidates in an efficient, cost-effective manner. Copyright © 2013 Elsevier Ltd. All rights reserved.

Computational neuroanatomy: ontology-based representation of neural components and connectivity

PubMed Central

Rubin, Daniel L; Talos, Ion-Florin; Halle, Michael; Musen, Mark A; Kikinis, Ron

2009-01-01

Background A critical challenge in neuroscience is organizing, managing, and accessing the explosion in neuroscientific knowledge, particularly anatomic knowledge. We believe that explicit knowledge-based approaches to make neuroscientific knowledge computationally accessible will be helpful in tackling this challenge and will enable a variety of applications exploiting this knowledge, such as surgical planning. Results We developed ontology-based models of neuroanatomy to enable symbolic lookup, logical inference and mathematical modeling of neural systems. We built a prototype model of the motor system that integrates descriptive anatomic and qualitative functional neuroanatomical knowledge. In addition to modeling normal neuroanatomy, our approach provides an explicit representation of abnormal neural connectivity in disease states, such as common movement disorders. The ontology-based representation encodes both structural and functional aspects of neuroanatomy. The ontology-based models can be evaluated computationally, enabling development of automated computer reasoning applications. Conclusion Neuroanatomical knowledge can be represented in machine-accessible format using ontologies. Computational neuroanatomical approaches such as described in this work could become a key tool in translational informatics, leading to decision support applications that inform and guide surgical planning and personalized care for neurological disease in the future. PMID:19208191

Preserving Smart Objects Privacy through Anonymous and Accountable Access Control for a M2M-Enabled Internet of Things

PubMed Central

Hernández-Ramos, José L.; Bernabe, Jorge Bernal; Moreno, M. Victoria; Skarmeta, Antonio F.

2015-01-01

As we get into the Internet of Things era, security and privacy concerns remain as the main obstacles in the development of innovative and valuable services to be exploited by society. Given the Machine-to-Machine (M2M) nature of these emerging scenarios, the application of current privacy-friendly technologies needs to be reconsidered and adapted to be deployed in such global ecosystem. This work proposes different privacy-preserving mechanisms through the application of anonymous credential systems and certificateless public key cryptography. The resulting alternatives are intended to enable an anonymous and accountable access control approach to be deployed on large-scale scenarios, such as Smart Cities. Furthermore, the proposed mechanisms have been deployed on constrained devices, in order to assess their suitability for a secure and privacy-preserving M2M-enabled Internet of Things. PMID:26140349

Preserving Smart Objects Privacy through Anonymous and Accountable Access Control for a M2M-Enabled Internet of Things.

PubMed

Hernández-Ramos, José L; Bernabe, Jorge Bernal; Moreno, M Victoria; Skarmeta, Antonio F

2015-07-01

As we get into the Internet of Things era, security and privacy concerns remain as the main obstacles in the development of innovative and valuable services to be exploited by society. Given the Machine-to-Machine (M2M) nature of these emerging scenarios, the application of current privacy-friendly technologies needs to be reconsidered and adapted to be deployed in such global ecosystem. This work proposes different privacy-preserving mechanisms through the application of anonymous credential systems and certificateless public key cryptography. The resulting alternatives are intended to enable an anonymous and accountable access control approach to be deployed on large-scale scenarios, such as Smart Cities. Furthermore, the proposed mechanisms have been deployed on constrained devices, in order to assess their suitability for a secure and privacy-preserving M2M-enabled Internet of Things.

Strategies of arteriovenous dialysis access.

PubMed

Weiswasser, Jonathan M; Kellicut, Dwight; Arora, Subodh; Sidawy, Anton N

2004-03-01

Surgical management of the patient who requires hemodialysis access, while continuing to demand more attention from the vascular surgeon, suffers from discrepancies of approach and strategy. With the increase in incidence of dialysis dependent renal failure among our population, many have attempted to present a uniform, logical strategy with which the vascular surgeon can most effectively treat the hemodialysis patient in the long term. Most notably, the multidisciplinary Dialysis Outcomes Quality Initiative (DOQI) guidelines present the surgeon with a rough outline of hemodialysis access insertion strategy, and it has become nationally recognized as an acceptable summary of treatment strategy and goals. The decision as to the most appropriate surgical access to offer a patient depends on immediate need for hemodialysis, history and physical examination findings, and suitability of available veins in the extremity. While percutaneous, catheter based access affords the luxury of immediate access, these devices suffer from several complicating factors, such as infection, and damage to large, proximal veins. For long-term access, the autogenous access, while perhaps less successful in the immediate short term, is always the preferred access type given its favorable longevity. The surgeons should focus on sites distally on the extremity, reserving proximal sites for potential future access insertions should the primary access fail. In the absence of suitable vein, prosthetic access may be considered. When both the upper and lower aspects of both upper extremities have been exhausted, the surgeon should consider access insertion elsewhere, such as the lower extremity.

Annotation of rule-based models with formal semantics to enable creation, analysis, reuse and visualization.

PubMed

Misirli, Goksel; Cavaliere, Matteo; Waites, William; Pocock, Matthew; Madsen, Curtis; Gilfellon, Owen; Honorato-Zimmer, Ricardo; Zuliani, Paolo; Danos, Vincent; Wipat, Anil

2016-03-15

Biological systems are complex and challenging to model and therefore model reuse is highly desirable. To promote model reuse, models should include both information about the specifics of simulations and the underlying biology in the form of metadata. The availability of computationally tractable metadata is especially important for the effective automated interpretation and processing of models. Metadata are typically represented as machine-readable annotations which enhance programmatic access to information about models. Rule-based languages have emerged as a modelling framework to represent the complexity of biological systems. Annotation approaches have been widely used for reaction-based formalisms such as SBML. However, rule-based languages still lack a rich annotation framework to add semantic information, such as machine-readable descriptions, to the components of a model. We present an annotation framework and guidelines for annotating rule-based models, encoded in the commonly used Kappa and BioNetGen languages. We adapt widely adopted annotation approaches to rule-based models. We initially propose a syntax to store machine-readable annotations and describe a mapping between rule-based modelling entities, such as agents and rules, and their annotations. We then describe an ontology to both annotate these models and capture the information contained therein, and demonstrate annotating these models using examples. Finally, we present a proof of concept tool for extracting annotations from a model that can be queried and analyzed in a uniform way. The uniform representation of the annotations can be used to facilitate the creation, analysis, reuse and visualization of rule-based models. Although examples are given, using specific implementations the proposed techniques can be applied to rule-based models in general. The annotation ontology for rule-based models can be found at http://purl.org/rbm/rbmo The krdf tool and associated executable examples are available at http://purl.org/rbm/rbmo/krdf anil.wipat@newcastle.ac.uk or vdanos@inf.ed.ac.uk. © The Author 2015. Published by Oxford University Press.

System and method for programmable bank selection for banked memory subsystems

DOEpatents

Blumrich, Matthias A.; Chen, Dong; Gara, Alan G.; Giampapa, Mark E.; Hoenicke, Dirk; Ohmacht, Martin; Salapura, Valentina; Sugavanam, Krishnan

2010-09-07

A programmable memory system and method for enabling one or more processor devices access to shared memory in a computing environment, the shared memory including one or more memory storage structures having addressable locations for storing data. The system comprises: one or more first logic devices associated with a respective one or more processor devices, each first logic device for receiving physical memory address signals and programmable for generating a respective memory storage structure select signal upon receipt of pre-determined address bit values at selected physical memory address bit locations; and, a second logic device responsive to each of the respective select signal for generating an address signal used for selecting a memory storage structure for processor access. The system thus enables each processor device of a computing environment memory storage access distributed across the one or more memory storage structures.

A Bookmarking Service for Organizing and Sharing URLs

NASA Technical Reports Server (NTRS)

Keller, Richard M.; Wolfe, Shawn R.; Chen, James R.; Mathe, Nathalie; Rabinowitz, Joshua L.

1997-01-01

Web browser bookmarking facilities predominate as the method of choice for managing URLs. In this paper, we describe some deficiencies of current bookmarking schemes, and examine an alternative to current approaches. We present WebTagger(TM), an implemented prototype of a personal bookmarking service that provides both individuals and groups with a customizable means of organizing and accessing Web-based information resources. In addition, the service enables users to supply feedback on the utility of these resources relative to their information needs, and provides dynamically-updated ranking of resources based on incremental user feedback. Individuals may access the service from anywhere on the Internet, and require no special software. This service greatly simplifies the process of sharing URLs within groups, in comparison with manual methods involving email. The underlying bookmark organization scheme is more natural and flexible than current hierarchical schemes supported by the major Web browsers, and enables rapid access to stored bookmarks.

The RCSB Protein Data Bank: views of structural biology for basic and applied research and education

PubMed Central

Rose, Peter W.; Prlić, Andreas; Bi, Chunxiao; Bluhm, Wolfgang F.; Christie, Cole H.; Dutta, Shuchismita; Green, Rachel Kramer; Goodsell, David S.; Westbrook, John D.; Woo, Jesse; Young, Jasmine; Zardecki, Christine; Berman, Helen M.; Bourne, Philip E.; Burley, Stephen K.

2015-01-01

The RCSB Protein Data Bank (RCSB PDB, http://www.rcsb.org) provides access to 3D structures of biological macromolecules and is one of the leading resources in biology and biomedicine worldwide. Our efforts over the past 2 years focused on enabling a deeper understanding of structural biology and providing new structural views of biology that support both basic and applied research and education. Herein, we describe recently introduced data annotations including integration with external biological resources, such as gene and drug databases, new visualization tools and improved support for the mobile web. We also describe access to data files, web services and open access software components to enable software developers to more effectively mine the PDB archive and related annotations. Our efforts are aimed at expanding the role of 3D structure in understanding biology and medicine. PMID:25428375

Fabrication of Highly Ordered Anodic Aluminium Oxide Templates on Silicon Substrates

DTIC Science & Technology

2007-01-01

highly ordered anodic aluminium oxide ( AAO ) templates of unprecedented pore uniformity directly on Si, enabled by new advances on two fronts – direct...field emitter, sensors, oscillators and photodetectors. 15. SUBJECT TERMS Anodic aluminum oxide , template-assisted nanofabrication, carbon nanotube...Fabrication of the aligned and patterned carbon nanotube field emitters using the anodic aluminum oxide nano-template on a Si wafer’, Synth. Met

Submicrometer Metallic Barcodes

NASA Astrophysics Data System (ADS)

Nicewarner-Peña, Sheila R.; Freeman, R. Griffith; Reiss, Brian D.; He, Lin; Peña, David J.; Walton, Ian D.; Cromer, Remy; Keating, Christine D.; Natan, Michael J.

2001-10-01

We synthesized multimetal microrods intrinsically encoded with submicrometer stripes. Complex striping patterns are readily prepared by sequential electrochemical deposition of metal ions into templates with uniformly sized pores. The differential reflectivity of adjacent stripes enables identification of the striping patterns by conventional light microscopy. This readout mechanism does not interfere with the use of fluorescence for detection of analytes bound to particles by affinity capture, as demonstrated by DNA and protein bioassays.

Cloud computing for context-aware enhanced m-Health services.

PubMed

Fernandez-Llatas, Carlos; Pileggi, Salvatore F; Ibañez, Gema; Valero, Zoe; Sala, Pilar

2015-01-01

m-Health services are increasing its presence in our lives due to the high penetration of new smartphone devices. This new scenario proposes new challenges in terms of information accessibility that require new paradigms which enable the new applications to access the data in a continuous and ubiquitous way, ensuring the privacy required depending on the kind of data accessed. This paper proposes an architecture based on cloud computing paradigms in order to empower new m-Health applications to enrich their results by providing secure access to user data.

Enabling the Differently-Abled

ERIC Educational Resources Information Center

Pal, Sonali

2009-01-01

It is perhaps unfortunate that enabling technologies do not come with an "ability warning", as they generally require the user to already have acquired a certain level of IT skills, in a similar way that online courses require users to have a certain level of prior IT knowledge. Accessing a computer and making the most of e-learning…

Defeating Inequalities in School Access: A Case of Children with Disabilities in Pakistan

ERIC Educational Resources Information Center

Hameed, Abdul; Manzoor, Afaf

2016-01-01

A recent study reveals that average distance from home to special school for children with disabilities in Punjab is about 11 km. A huge and free transport system is established to overcome the distance barrier. Moreover, the incentives such as free uniform, books, assistive devices and hostel facility along with subsistence allowance of Rs.800…

The Invisible Obstacle to Educational Equality: Gender Bias in Textbooks

ERIC Educational Resources Information Center

Blumberg, Rae Lesser

2008-01-01

Gender bias in textbooks (GBIT) is a low-profile education issue, given the 72,000,000 children who still have no access to schooling, but this article argues that GBIT is: (1) an important, (2) near-universal, (3) remarkably uniform, (4) quite persistent but (5) virtually invisible obstacle on the road to gender equality in education--an obstacle…

A Note of Caution: The International CPA Designation

ERIC Educational Resources Information Center

Kerr, Stephen G.

2011-01-01

The National Association of State Boards of Accountancy (NASBA) is pursuing initiatives to make the U.S. Uniform CPA Examination more accessible to candidates outside of the United States. At the heart of their plan is a desire to ensure that the U.S.-CPA retains its position as a gold standard in the world of professional accountancy. Over the…

77 FR 66898 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-07

... member organizations for which the Exchange is the DEA do not have access to the Form BR filing process... the Uniform Branch Office Registration Form (Form BR). Specifically, the Exchange is proposing that... mechanism of a free and open market and a national market system and, in general, to protect investors and...

17 CFR 249.446 - Form ID, uniform application for access codes to file on EDGAR.

Code of Federal Regulations, 2011 CFR

2011-04-01

... log on to the EDGAR system, submit filings, and change its CCC. (d) Password Modification Authorization Code (PMAC)—allows a filer, filing agent or training agent to change its Password. [69 FR 22710... Sections Affected, which appears in the Finding Aids section of the printed volume and at at www.fdsys.gov. ...

17 CFR 269.7 - Form ID, uniform application for access codes to file on EDGAR.

Code of Federal Regulations, 2011 CFR

2011-04-01

... on to the EDGAR system, submit filings, and change its CCC. (d) Password Modification Authorization Code (PMAC)—allows a filer, filing agent or training agent to change its Password. [69 FR 22710, Apr... Sections Affected, which appears in the Finding Aids section of the printed volume and at at www.fdsys.gov. ...

Morphological, chemical and molecular characterization of Centella asiatica germplasms for commercial cultivation in the Indo-Gangetic plains.

PubMed

Prasad, Archana; Dhawan, Sunita S; Mathur, Ajay K; Prakash, Om; Gupta, Madan M; Verma, Ram K; Lal, Raj K; Mathur, Archana

2014-06-01

Centella asiatica germplasm collected from north, north-eastern and southern parts of India was compared for biomass and centellosides productivity under uniform agro-climatic conditions of the Indo-Gangetic plains at Lucknow. The highest biomass accumulation (411.9 g FW/m2 area) was recorded in accession A from north India, followed by 284.0, 135.7 and 29.2 g FW/m2 in accessions M, B and E from southern, eastern and north-eastern regions, respectively. Accession M possessed the highest asiaticoside content (52.1 mg/gDW) that was 1.58, 2.34 and 21.7 folds more than accessions A, B and E, respectively. The madecassoside level in leaves of accessions B and M was comparable (28.9 and 25.7 mg/gDW) and two folds more than accession A (13.9 mg/gDW). The madecassic and asiatic acid content in leaf tissue of all four accessions remained low in Lucknow. Amplified fragment length polymorphism (AFLP) analysis with 23 primers yielded 696 fragments, 563 of which were polymorphic. Accession M out-grouped with genetic dissimilarity indices of 83, 85 and 95% from accessions A, E and B, respectively. Commercial cultivation of accessions M and A through a four months growth cycle (June to September) in agro-climatic conditions of the Indo-Gangetic plains is suggested.

Electron polar cap and the boundary of open geomagnetic field lines.

NASA Technical Reports Server (NTRS)

Evans, L. C.; Stone, E. C.

1972-01-01

A total of 333 observations of the boundary of the polar access region for electrons (energies greater than 530 keV) provides a comprehensive map of the electron polar cap. The boundary of the electron polar cap, which should occur at the latitude separating open and closed field lines, is consistent with previously reported closed field line limits determined from trapped-particle data. The boundary, which is sharply defined, seems to occur at one of three discrete latitudes. Although the electron flux is generally uniform across the polar cap, a limited region of reduced access is observed about 10% of the time.

MaizeGDB: Global support for maize research through open access information [abstract

USDA-ARS?s Scientific Manuscript database

MaizeGDB is the open-access global repository for maize genetic and genomic information – from single genes that determine nutritional quality to whole genome-scale data for complex traits including yield and drought tolerance. The data and tools at MaizeGDB enable researchers from Ethiopia to Ghan...

Leading the Way: Access. 2013-18 Master Plan

ERIC Educational Resources Information Center

West Virginia Higher Education Policy Commission, 2013

2013-01-01

The 2013-18 West Virginia Higher Education Policy Commission master plan, "Leading the Way: Access. Success. Impact" was developed to provide a programmatic framework and goals to enable the state's system of public four-year institutions to meet the educational needs of West Virginians. A state economy in flux with declining revenues…

Understanding and Creating Accessible Touch Screen Interactions for Blind People

ERIC Educational Resources Information Center

Kane, Shaun K.

2011-01-01

Using touch screens presents a number of usability and accessibility challenges for blind people. Most touch screen-based user interfaces are optimized for visual interaction, and are therefore difficult or impossible to use without vision. This dissertation presents an approach to redesigning gesture-based user interfaces to enable blind people…

Maximizing Access Technology Tools for the Library of the Future

ERIC Educational Resources Information Center

Pearson, Waynn

2003-01-01

The renovated Cerritos Public Library is a unique blending of traditional and hightech features. One of the key principles in its planning and design was to enable a range of convenient access services. This article summarizes the process of building this library and how it has been received by users. (Contains 5 figures.)

Effects of Practice Type in the Here and Now Mobile Learning Environment

ERIC Educational Resources Information Center

Tutty, Jeremy I.; Martin, Florence

2014-01-01

This generation of technology is characterized by mobile and portable devices such as smartphones and tablet computers with wireless broadband access. Mobile technologies enable a new kind of learning called "here and now learning," where learners have access to information anytime and anywhere to perform authentic activities in the…

Spacecraft Demand Access: Autonomy for Low-Cost Planetary Operations

NASA Technical Reports Server (NTRS)

Sweetnam, Donald

1997-01-01

In this paper we describe a new concept and prototype for dramtically reducing the cost of contact with planetary spacecraft. Known as spacecraft Demand Access, a suite of spacecraft and ground automation technologies, it enables future intelligent spacecraft to act as initiators of cost effective contact with the ground - doing it only when necessary.

SECIMTools: a suite of metabolomics data analysis tools.

PubMed

Kirpich, Alexander S; Ibarra, Miguel; Moskalenko, Oleksandr; Fear, Justin M; Gerken, Joseph; Mi, Xinlei; Ashrafi, Ali; Morse, Alison M; McIntyre, Lauren M

2018-04-20

Metabolomics has the promise to transform the area of personalized medicine with the rapid development of high throughput technology for untargeted analysis of metabolites. Open access, easy to use, analytic tools that are broadly accessible to the biological community need to be developed. While technology used in metabolomics varies, most metabolomics studies have a set of features identified. Galaxy is an open access platform that enables scientists at all levels to interact with big data. Galaxy promotes reproducibility by saving histories and enabling the sharing workflows among scientists. SECIMTools (SouthEast Center for Integrated Metabolomics) is a set of Python applications that are available both as standalone tools and wrapped for use in Galaxy. The suite includes a comprehensive set of quality control metrics (retention time window evaluation and various peak evaluation tools), visualization techniques (hierarchical cluster heatmap, principal component analysis, modular modularity clustering), basic statistical analysis methods (partial least squares - discriminant analysis, analysis of variance, t-test, Kruskal-Wallis non-parametric test), advanced classification methods (random forest, support vector machines), and advanced variable selection tools (least absolute shrinkage and selection operator LASSO and Elastic Net). SECIMTools leverages the Galaxy platform and enables integrated workflows for metabolomics data analysis made from building blocks designed for easy use and interpretability. Standard data formats and a set of utilities allow arbitrary linkages between tools to encourage novel workflow designs. The Galaxy framework enables future data integration for metabolomics studies with other omics data.

In what ways do communities support optimal antiretroviral treatment in Zimbabwe?

PubMed

Scott, K; Campbell, C; Madanhire, C; Skovdal, M; Nyamukapa, C; Gregson, S

2014-12-01

Little research has been conducted on how pre-existing indigenous community resources, especially social networks, affect the success of externally imposed HIV interventions. Antiretroviral treatment (ART), an externally initiated biomedical intervention, is being rolled out across sub-Saharan Africa. Understanding the ways in which community networks are working to facilitate optimal ART access and adherence will enable policymakers to better engage with and bolster these pre-existing resources. We conducted 67 interviews and eight focus group discussions with 127 people from three key population groups in Manicaland, eastern Zimbabwe: healthcare workers, adults on ART and carers of children on ART. We also observed over 100 h of HIV treatment sites at local clinics and hospitals. Our research sought to determine how indigenous resources were enabling people to achieve optimal ART access and adherence. We analysed data transcripts using thematic network technique, coding references to supportive community networks that enable local people to achieve ART access and adherence. People on ART or carers of children on ART in Zimbabwe report drawing support from a variety of social networks that enable them to overcome many obstacles to adherence. Key support networks include: HIV groups; food and income support networks; home-based care, church and women's groups; family networks; and relationships with healthcare providers. More attention to the community context in which HIV initiatives occur will help ensure that interventions work with and benefit from pre-existing social capital. © The Author (2013). Published by Oxford University Press.

Zero-Copy Objects System

NASA Technical Reports Server (NTRS)

Burleigh, Scott C.

2011-01-01

Zero-Copy Objects System software enables application data to be encapsulated in layers of communication protocol without being copied. Indirect referencing enables application source data, either in memory or in a file, to be encapsulated in place within an unlimited number of protocol headers and/or trailers. Zero-copy objects (ZCOs) are abstract data access representations designed to minimize I/O (input/output) in the encapsulation of application source data within one or more layers of communication protocol structure. They are constructed within the heap space of a Simple Data Recorder (SDR) data store to which all participating layers of the stack must have access. Each ZCO contains general information enabling access to the core source data object (an item of application data), together with (a) a linked list of zero or more specific extents that reference portions of this source data object, and (b) linked lists of protocol header and trailer capsules. The concatenation of the headers (in ascending stack sequence), the source data object extents, and the trailers (in descending stack sequence) constitute the transmitted data object constructed from the ZCO. This scheme enables a source data object to be encapsulated in a succession of protocol layers without ever having to be copied from a buffer at one layer of the protocol stack to an encapsulating buffer at a lower layer of the stack. For large source data objects, the savings in copy time and reduction in memory consumption may be considerable.

In what ways do communities support optimal antiretroviral treatment in Zimbabwe?

PubMed Central

Scott, K.; Campbell, C.; Madanhire, C.; Skovdal, M.; Nyamukapa, C.; Gregson, S.

2014-01-01

Little research has been conducted on how pre-existing indigenous community resources, especially social networks, affect the success of externally imposed HIV interventions. Antiretroviral treatment (ART), an externally initiated biomedical intervention, is being rolled out across sub-Saharan Africa. Understanding the ways in which community networks are working to facilitate optimal ART access and adherence will enable policymakers to better engage with and bolster these pre-existing resources. We conducted 67 interviews and eight focus group discussions with 127 people from three key population groups in Manicaland, eastern Zimbabwe: healthcare workers, adults on ART and carers of children on ART. We also observed over 100 h of HIV treatment sites at local clinics and hospitals. Our research sought to determine how indigenous resources were enabling people to achieve optimal ART access and adherence. We analysed data transcripts using thematic network technique, coding references to supportive community networks that enable local people to achieve ART access and adherence. People on ART or carers of children on ART in Zimbabwe report drawing support from a variety of social networks that enable them to overcome many obstacles to adherence. Key support networks include: HIV groups; food and income support networks; home-based care, church and women's groups; family networks; and relationships with healthcare providers. More attention to the community context in which HIV initiatives occur will help ensure that interventions work with and benefit from pre-existing social capital. PMID:23503291

Total centralisation and optimisation of an oncology management suite via Citrix®

NASA Astrophysics Data System (ADS)

James, C.; Frantzis, J.; Ripps, L.; Fenton, P.

2014-03-01

The management of patient information and treatment planning is traditionally an intra-departmental requirement of a radiation oncology service. Epworth Radiation Oncology systems must support the transient nature of Visiting Medical Officers (VMOs). This unique work practice created challenges when implementing the vision of a completely paperless solution that allows for a responsive and efficient service delivery. ARIA® and EclipseTM (Varian Medical Systems, Palo Alto, CA, USA) have been deployed across four dedicated Citrix® (Citrix Systems, Santa Clara, CA, USA) servers allowing VMOs to access these applications remotely. A range of paperless solutions were developed within ARIA® to facilitate clinical and organisational management whilst optimising efficient work practices. The IT infrastructure and paperless workflow has enabled VMOs to securely access the VarianTM (Varian Medical Systems, Palo Alto, CA, USA) oncology software and experience full functionality from any location on multiple devices. This has enhanced access to patient information and improved the responsiveness of the service. Epworth HealthCare has developed a unique solution to enable remote access to a centralised oncology management suite, while maintaining a secure and paperless working environment.

Kokkos: Enabling manycore performance portability through polymorphic memory access patterns

DOE PAGES

Carter Edwards, H.; Trott, Christian R.; Sunderland, Daniel

2014-07-22

The manycore revolution can be characterized by increasing thread counts, decreasing memory per thread, and diversity of continually evolving manycore architectures. High performance computing (HPC) applications and libraries must exploit increasingly finer levels of parallelism within their codes to sustain scalability on these devices. We found that a major obstacle to performance portability is the diverse and conflicting set of constraints on memory access patterns across devices. Contemporary portable programming models address manycore parallelism (e.g., OpenMP, OpenACC, OpenCL) but fail to address memory access patterns. The Kokkos C++ library enables applications and domain libraries to achieve performance portability on diversemore » manycore architectures by unifying abstractions for both fine-grain data parallelism and memory access patterns. In this paper we describe Kokkos’ abstractions, summarize its application programmer interface (API), present performance results for unit-test kernels and mini-applications, and outline an incremental strategy for migrating legacy C++ codes to Kokkos. Furthermore, the Kokkos library is under active research and development to incorporate capabilities from new generations of manycore architectures, and to address a growing list of applications and domain libraries.« less

Digital Health Services and Digital Identity in Alberta.

PubMed

McEachern, Aiden; Cholewa, David

2017-01-01

The Government of Alberta continues to improve delivery of healthcare by allowing Albertans to access their health information online. Alberta is the only province in Canada with provincial electronic health records for all its citizens. These records are currently made available to medical practitioners, but Alberta Health believes that providing Albertans access to their health records will transform the delivery of healthcare in Alberta. It is important to have a high level of assurance that the health records are provided to the correct Albertan. Alberta Health requires a way for Albertans to obtain a digital identity with a high level of identity assurance prior to releasing health records via the Personal Health Portal. Service Alberta developed the MyAlberta Digital ID program to provide a digital identity verification service. The Ministry of Health is leveraging MyAlberta Digital ID to enable Albertans to access their personal health records through the Personal Health Portal. The Government of Alberta is advancing its vision of patient-centred healthcare by enabling Albertans to access a trusted source for health information and their electronic health records using a secure digital identity.

Optimising LAN access to grid enabled storage elements

NASA Astrophysics Data System (ADS)

Stewart, G. A.; Cowan, G. A.; Dunne, B.; Elwell, A.; Millar, A. P.

2008-07-01

When operational, the Large Hadron Collider experiments at CERN will collect tens of petabytes of physics data per year. The worldwide LHC computing grid (WLCG) will distribute this data to over two hundred Tier-1 and Tier-2 computing centres, enabling particle physicists around the globe to access the data for analysis. Although different middleware solutions exist for effective management of storage systems at collaborating institutes, the patterns of access envisaged for Tier-2s fall into two distinct categories. The first involves bulk transfer of data between different Grid storage elements using protocols such as GridFTP. This data movement will principally involve writing ESD and AOD files into Tier-2 storage. Secondly, once datasets are stored at a Tier-2, physics analysis jobs will read the data from the local SE. Such jobs require a POSIX-like interface to the storage so that individual physics events can be extracted. In this paper we consider the performance of POSIX-like access to files held in Disk Pool Manager (DPM) storage elements, a popular lightweight SRM storage manager from EGEE.

Portable and Error-Free DNA-Based Data Storage.

PubMed

Yazdi, S M Hossein Tabatabaei; Gabrys, Ryan; Milenkovic, Olgica

2017-07-10

DNA-based data storage is an emerging nonvolatile memory technology of potentially unprecedented density, durability, and replication efficiency. The basic system implementation steps include synthesizing DNA strings that contain user information and subsequently retrieving them via high-throughput sequencing technologies. Existing architectures enable reading and writing but do not offer random-access and error-free data recovery from low-cost, portable devices, which is crucial for making the storage technology competitive with classical recorders. Here we show for the first time that a portable, random-access platform may be implemented in practice using nanopore sequencers. The novelty of our approach is to design an integrated processing pipeline that encodes data to avoid costly synthesis and sequencing errors, enables random access through addressing, and leverages efficient portable sequencing via new iterative alignment and deletion error-correcting codes. Our work represents the only known random access DNA-based data storage system that uses error-prone nanopore sequencers, while still producing error-free readouts with the highest reported information rate/density. As such, it represents a crucial step towards practical employment of DNA molecules as storage media.

Large area pulsed solar simulator

NASA Technical Reports Server (NTRS)

Kruer, Mark A. (Inventor)

1999-01-01

An advanced solar simulator illuminates the surface a very large solar array, such as one twenty feet by twenty feet in area, from a distance of about twenty-six feet with an essentially uniform intensity field of pulsed light of an intensity of one AMO, enabling the solar array to be efficiently tested with light that emulates the sun. Light modifiers sculpt a portion of the light generated by an electrically powered high power Xenon lamp and together with direct light from the lamp provide uniform intensity illumination throughout the solar array, compensating for the square law and cosine law reduction in direct light intensity, particularly at the corner locations of the array. At any location within the array the sum of the direct light and reflected light is essentially constant.

Data management and analysis for the Earth System Grid

NASA Astrophysics Data System (ADS)

Williams, D. N.; Ananthakrishnan, R.; Bernholdt, D. E.; Bharathi, S.; Brown, D.; Chen, M.; Chervenak, A. L.; Cinquini, L.; Drach, R.; Foster, I. T.; Fox, P.; Hankin, S.; Henson, V. E.; Jones, P.; Middleton, D. E.; Schwidder, J.; Schweitzer, R.; Schuler, R.; Shoshani, A.; Siebenlist, F.; Sim, A.; Strand, W. G.; Wilhelmi, N.; Su, M.

2008-07-01

The international climate community is expected to generate hundreds of petabytes of simulation data within the next five to seven years. This data must be accessed and analyzed by thousands of analysts worldwide in order to provide accurate and timely estimates of the likely impact of climate change on physical, biological, and human systems. Climate change is thus not only a scientific challenge of the first order but also a major technological challenge. In order to address this technological challenge, the Earth System Grid Center for Enabling Technologies (ESG-CET) has been established within the U.S. Department of Energy's Scientific Discovery through Advanced Computing (SciDAC)-2 program, with support from the offices of Advanced Scientific Computing Research and Biological and Environmental Research. ESG-CET's mission is to provide climate researchers worldwide with access to the data, information, models, analysis tools, and computational capabilities required to make sense of enormous climate simulation datasets. Its specific goals are to (1) make data more useful to climate researchers by developing Grid technology that enhances data usability; (2) meet specific distributed database, data access, and data movement needs of national and international climate projects; (3) provide a universal and secure web-based data access portal for broad multi-model data collections; and (4) provide a wide-range of Grid-enabled climate data analysis tools and diagnostic methods to international climate centers and U.S. government agencies. Building on the successes of the previous Earth System Grid (ESG) project, which has enabled thousands of researchers to access tens of terabytes of data from a small number of ESG sites, ESG-CET is working to integrate a far larger number of distributed data providers, high-bandwidth wide-area networks, and remote computers in a highly collaborative problem-solving environment.

p-BioSPRE—an information and communication technology framework for transnational biomaterial sharing and access

PubMed Central

Weiler, Gabriele; Schröder, Christina; Schera, Fatima; Dobkowicz, Matthias; Kiefer, Stephan; Heidtke, Karsten R; Hänold, Stefanie; Nwankwo, Iheanyi; Forgó, Nikolaus; Stanulla, Martin; Eckert, Cornelia; Graf, Norbert

2014-01-01

Biobanks represent key resources for clinico-genomic research and are needed to pave the way to personalised medicine. To achieve this goal, it is crucial that scientists can securely access and share high-quality biomaterial and related data. Therefore, there is a growing interest in integrating biobanks into larger biomedical information and communication technology (ICT) infrastructures. The European project p-medicine is currently building an innovative ICT infrastructure to meet this need. This platform provides tools and services for conducting research and clinical trials in personalised medicine. In this paper, we describe one of its main components, the biobank access framework p-BioSPRE (p-medicine Biospecimen Search and Project Request Engine). This generic framework enables and simplifies access to existing biobanks, but also to offer own biomaterial collections to research communities, and to manage biobank specimens and related clinical data over the ObTiMA Trial Biomaterial Manager. p-BioSPRE takes into consideration all relevant ethical and legal standards, e.g., safeguarding donors’ personal rights and enabling biobanks to keep control over the donated material and related data. The framework thus enables secure sharing of biomaterial within open and closed research communities, while flexibly integrating related clinical and omics data. Although the development of the framework is mainly driven by user scenarios from the cancer domain, in this case, acute lymphoblastic leukaemia and Wilms tumour, it can be extended to further disease entities. PMID:24567758

Data governance and stewardship: designing data stewardship entities and advancing data access.

PubMed

Rosenbaum, Sara

2010-10-01

U.S. health policy is engaged in a struggle over access to health information, in particular, the conditions under which information should be accessible for research when appropriate privacy protections and security safeguards are in place. The expanded use of health information-an inevitable step in an information age-is widely considered be essential to health system reform. Models exist for the creation of data-sharing arrangements that promote proper use of information in a safe and secure environment and with attention to ethical standards. Data stewardship is a concept with deep roots in the science and practice of data collection, sharing, and analysis. Reflecting the values of fair information practice, data stewardship denotes an approach to the management of data, particularly data that can identify individuals. The concept of a data steward is intended to convey a fiduciary (or trust) level of responsibility toward the data. Data governance is the process by which responsibilities of stewardship are conceptualized and carried out. As the concept of health information data stewardship advances in a technology-enabled environment, the question is whether legal barriers to data access and use will begin to give way. One possible answer may lie in defining the public interest in certain data uses, tying provider participation in federal health programs to the release of all-payer data to recognized data stewardship entities for aggregation and management, and enabling such entities to foster and enable the creation of knowledge through research. © Health Research and Educational Trust.

Data Governance and Stewardship: Designing Data Stewardship Entities and Advancing Data Access

PubMed Central

Rosenbaum, Sara

2010-01-01

U.S. health policy is engaged in a struggle over access to health information, in particular, the conditions under which information should be accessible for research when appropriate privacy protections and security safeguards are in place. The expanded use of health information—an inevitable step in an information age—is widely considered be essential to health system reform. Models exist for the creation of data-sharing arrangements that promote proper use of information in a safe and secure environment and with attention to ethical standards. Data stewardship is a concept with deep roots in the science and practice of data collection, sharing, and analysis. Reflecting the values of fair information practice, data stewardship denotes an approach to the management of data, particularly data that can identify individuals. The concept of a data steward is intended to convey a fiduciary (or trust) level of responsibility toward the data. Data governance is the process by which responsibilities of stewardship are conceptualized and carried out. As the concept of health information data stewardship advances in a technology-enabled environment, the question is whether legal barriers to data access and use will begin to give way. One possible answer may lie in defining the public interest in certain data uses, tying provider participation in federal health programs to the release of all-payer data to recognized data stewardship entities for aggregation and management, and enabling such entities to foster and enable the creation of knowledge through research. PMID:21054365

Subtitle Synchronization across Multiple Screens and Devices

PubMed Central

Rodriguez-Alsina, Aitor; Talavera, Guillermo; Orero, Pilar; Carrabina, Jordi

2012-01-01

Ambient Intelligence is a new paradigm in which environments are sensitive and responsive to the presence of people. This is having an increasing importance in multimedia applications, which frequently rely on sensors to provide useful information to the user. In this context, multimedia applications must adapt and personalize both content and interfaces in order to reach acceptable levels of context-specific quality of service for the user, and enable the content to be available anywhere and at any time. The next step is to make content available to everybody in order to overcome the existing access barriers to content for users with specific needs, or else to adapt to different platforms, hence making content fully usable and accessible. Appropriate access to video content, for instance, is not always possible due to the technical limitations of traditional video packaging, transmission and presentation. This restricts the flexibility of subtitles and audio-descriptions to be adapted to different devices, contexts and users. New Web standards built around HTML5 enable more featured applications with better adaptation and personalization facilities, and thus would seem more suitable for accessible AmI environments. This work presents a video subtitling system that enables the customization, adaptation and synchronization of subtitles across different devices and multiple screens. The benefits of HTML5 applications for building the solution are analyzed along with their current platform support. Moreover, examples of the use of the application in three different cases are presented. Finally, the user experience of the solution is evaluated. PMID:23012513

Subtitle synchronization across multiple screens and devices.

PubMed

Rodriguez-Alsina, Aitor; Talavera, Guillermo; Orero, Pilar; Carrabina, Jordi

2012-01-01

Ambient Intelligence is a new paradigm in which environments are sensitive and responsive to the presence of people. This is having an increasing importance in multimedia applications, which frequently rely on sensors to provide useful information to the user. In this context, multimedia applications must adapt and personalize both content and interfaces in order to reach acceptable levels of context-specific quality of service for the user, and enable the content to be available anywhere and at any time. The next step is to make content available to everybody in order to overcome the existing access barriers to content for users with specific needs, or else to adapt to different platforms, hence making content fully usable and accessible. Appropriate access to video content, for instance, is not always possible due to the technical limitations of traditional video packaging, transmission and presentation. This restricts the flexibility of subtitles and audio-descriptions to be adapted to different devices, contexts and users. New Web standards built around HTML5 enable more featured applications with better adaptation and personalization facilities, and thus would seem more suitable for accessible AmI environments. This work presents a video subtitling system that enables the customization, adaptation and synchronization of subtitles across different devices and multiple screens. The benefits of HTML5 applications for building the solution are analyzed along with their current platform support. Moreover, examples of the use of the application in three different cases are presented. Finally, the user experience of the solution is evaluated.

Dynamic mask for producing uniform or graded-thickness thin films

DOEpatents

Folta, James A [Livermore, CA

2006-06-13

A method for producing single layer or multilayer films with high thickness uniformity or thickness gradients. The method utilizes a moving mask which blocks some of the flux from a sputter target or evaporation source before it deposits on a substrate. The velocity and position of the mask is computer controlled to precisely tailor the film thickness distribution. The method is applicable to any type of vapor deposition system, but is particularly useful for ion beam sputter deposition and evaporation deposition; and enables a high degree of uniformity for ion beam deposition, even for near-normal incidence of deposition species, which may be critical for producing low-defect multilayer coatings, such as required for masks for extreme ultraviolet lithography (EUVL). The mask can have a variety of shapes, from a simple solid paddle shape to a larger mask with a shaped hole through which the flux passes. The motion of the mask can be linear or rotational, and the mask can be moved to make single or multiple passes in front of the substrate per layer, and can pass completely or partially across the substrate.

Backwards compatible high dynamic range video compression

NASA Astrophysics Data System (ADS)

Dolzhenko, Vladimir; Chesnokov, Vyacheslav; Edirisinghe, Eran A.

2014-02-01

This paper presents a two layer CODEC architecture for high dynamic range video compression. The base layer contains the tone mapped video stream encoded with 8 bits per component which can be decoded using conventional equipment. The base layer content is optimized for rendering on low dynamic range displays. The enhancement layer contains the image difference, in perceptually uniform color space, between the result of inverse tone mapped base layer content and the original video stream. Prediction of the high dynamic range content reduces the redundancy in the transmitted data while still preserves highlights and out-of-gamut colors. Perceptually uniform colorspace enables using standard ratedistortion optimization algorithms. We present techniques for efficient implementation and encoding of non-uniform tone mapping operators with low overhead in terms of bitstream size and number of operations. The transform representation is based on human vision system model and suitable for global and local tone mapping operators. The compression techniques include predicting the transform parameters from previously decoded frames and from already decoded data for current frame. Different video compression techniques are compared: backwards compatible and non-backwards compatible using AVC and HEVC codecs.

Empowering file-based radio production through media asset management systems

NASA Astrophysics Data System (ADS)

Muylaert, Bjorn; Beckers, Tom

2006-10-01

In recent years, IT-based production and archiving of media has matured to a level which enables broadcasters to switch over from tape- or CD-based to file-based workflows for the production of their radio and television programs. This technology is essential for the future of broadcasters as it provides the flexibility and speed of execution the customer demands by enabling, among others, concurrent access and production, faster than real-time ingest, edit during ingest, centrally managed annotation and quality preservation of media. In terms of automation of program production, the radio department is the most advanced within the VRT, the Flemish broadcaster. Since a couple of years ago, the radio department has been working with digital equipment and producing its programs mainly on standard IT equipment. Historically, the shift from analogue to digital based production has been a step by step process initiated and coordinated by each radio station separately, resulting in a multitude of tools and metadata collections, some of them developed in-house, lacking integration. To make matters worse, each of those stations adopted a slightly different production methodology. The planned introduction of a company-wide Media Asset Management System allows a coordinated overhaul to a unified production architecture. Benefits include the centralized ingest and annotation of audio material and the uniform, integrated (in terms of IT infrastructure) workflow model. Needless to say, the ingest strategy, metadata management and integration with radio production systems play a major role in the level of success of any improvement effort. This paper presents a data model for audio-specific concepts relevant to radio production. It includes an investigation of ingest techniques and strategies. Cooperation with external, professional production tools is demonstrated through a use-case scenario: the integration of an existing, multi-track editing tool with a commercially available Media Asset Management System. This will enable an uncomplicated production chain, with a recognizable look and feel for all system users, regardless of their affiliated radio station, as well as central retrieval and storage of information and metadata.

A Parallel Vector Machine for the PM Programming Language

NASA Astrophysics Data System (ADS)

Bellerby, Tim

2016-04-01

PM is a new programming language which aims to make the writing of computational geoscience models on parallel hardware accessible to scientists who are not themselves expert parallel programmers. It is based around the concept of communicating operators: language constructs that enable variables local to a single invocation of a parallelised loop to be viewed as if they were arrays spanning the entire loop domain. This mechanism enables different loop invocations (which may or may not be executing on different processors) to exchange information in a manner that extends the successful Communicating Sequential Processes idiom from single messages to collective communication. Communicating operators avoid the additional synchronisation mechanisms, such as atomic variables, required when programming using the Partitioned Global Address Space (PGAS) paradigm. Using a single loop invocation as the fundamental unit of concurrency enables PM to uniformly represent different levels of parallelism from vector operations through shared memory systems to distributed grids. This paper describes an implementation of PM based on a vectorised virtual machine. On a single processor node, concurrent operations are implemented using masked vector operations. Virtual machine instructions operate on vectors of values and may be unmasked, masked using a Boolean field, or masked using an array of active vector cell locations. Conditional structures (such as if-then-else or while statement implementations) calculate and apply masks to the operations they control. A shift in mask representation from Boolean to location-list occurs when active locations become sufficiently sparse. Parallel loops unfold data structures (or vectors of data structures for nested loops) into vectors of values that may additionally be distributed over multiple computational nodes and then split into micro-threads compatible with the size of the local cache. Inter-node communication is accomplished using standard OpenMP and MPI. Performance analyses of the PM vector machine, demonstrating its scaling properties with respect to domain size and the number of processor nodes will be presented for a range of hardware configurations. The PM software and language definition are being made available under unrestrictive MIT and Creative Commons Attribution licenses respectively: www.pm-lang.org.

CAD Services: an Industry Standard Interface for Mechanical CAD Interoperability

NASA Technical Reports Server (NTRS)

Claus, Russell; Weitzer, Ilan

2002-01-01

Most organizations seek to design and develop new products in increasingly shorter time periods. At the same time, increased performance demands require a team-based multidisciplinary design process that may span several organizations. One approach to meet these demands is to use 'Geometry Centric' design. In this approach, design engineers team their efforts through one united representation of the design that is usually captured in a CAD system. Standards-based interfaces are critical to provide uniform, simple, distributed services that enable the 'Geometry Centric' design approach. This paper describes an industry-wide effort, under the Object Management Group's (OMG) Manufacturing Domain Task Force, to define interfaces that enable the interoperability of CAD, Computer Aided Manufacturing (CAM), and Computer Aided Engineering (CAE) tools. This critical link to enable 'Geometry Centric' design is called: Cad Services V1.0. This paper discusses the features of this standard and proposed application.

NFFA-Europe: enhancing European competitiveness in nanoscience research and innovation (Conference Presentation)

NASA Astrophysics Data System (ADS)

Carsughi, Flavio; Fonseca, Luis

2017-06-01

NFFA-EUROPE is an European open access resource for experimental and theoretical nanoscience and sets out a platform to carry out comprehensive projects for multidisciplinary research at the nanoscale extending from synthesis to nanocharacterization to theory and numerical simulation. Advanced infrastructures specialized on growth, nano-lithography, nano-characterization, theory and simulation and fine-analysis with Synchrotron, FEL and Neutron radiation sources are integrated in a multi-site combination to develop frontier research on methods for reproducible nanoscience research and to enable European and international researchers from diverse disciplines to carry out advanced proposals impacting science and innovation. NFFA-EUROPE will enable coordinated access to infrastructures on different aspects of nanoscience research that is not currently available at single specialized ones and without duplicating their specific scopes. Approved user projects will have access to the best suited instruments and support competences for performing the research, including access to analytical large scale facilities, theory and simulation and high-performance computing facilities. Access is offered free of charge to European users and users will receive a financial contribution for their travel, accommodation and subsistence costs. The users access will include several "installations" and will be coordinated through a single entry point portal that will activate an advanced user-infrastructure dialogue to build up a personalized access programme with an increasing return on science and innovation production. The own research activity of NFFA-EUROPE will address key bottlenecks of nanoscience research: nanostructure traceability, protocol reproducibility, in-operando nano-manipulation and analysis, open data.