[The application of computer aided design and computer aided engineering technique in separation of Pygopagus conjoined twins].

PubMed

Zhang, Zhi-cheng; Sun, Tian-sheng; Li, Fang; Tang, Guo-lin

2009-05-19

To explore the effect of CAD and CAE related technique in separation of Pygopagus Conjoined Twins. CT images of Pygopagus conjoined twins were obtained and reconstructed in three-dimensional by Mimics software. 3D entity model of skin and spine of conjoined twins were made by fast plastic technique and equipment according to 3D data model. The circumference and area of fused and independent dural sac were measured by software of AutoCAD. The entity model is real reflection of skin and spine of Pygopagus. It was used in the procedures of discussion, sham operation, skin flap design and informed consent. In the measure of MRI, the circumference and area of fused dural sac was more than of independent dural sac, that is to say, the defect of dural sac can be repaired by direct suture. The intraoperative finding match with imaging measure results. The application of CAD and CAE in the procedure of preoperative plan have gave big help to successful separation of Pygopagus Conjoined Twins.

Next Generation CAD/CAM/CAE Systems

NASA Technical Reports Server (NTRS)

Noor, Ahmed K. (Compiler); Malone, John B. (Compiler)

1997-01-01

This document contains presentations from the joint UVA/NASA Workshop on Next Generation CAD/CAM/CAE Systems held at NASA Langley Research Center in Hampton, Virginia on March 18-19, 1997. The presentations focused on current capabilities and future directions of CAD/CAM/CAE systems, aerospace industry projects, and university activities related to simulation-based design. Workshop attendees represented NASA, commercial software developers, the aerospace industry, government labs, and academia. The workshop objectives were to assess the potential of emerging CAD/CAM/CAE technology for use in intelligent simulation-based design and to provide guidelines for focused future research leading to effective use of CAE systems for simulating the entire life cycle of aerospace systems.

An automation of design and modelling tasks in NX Siemens environment with original software - generator module

NASA Astrophysics Data System (ADS)

Zbiciak, M.; Grabowik, C.; Janik, W.

2015-11-01

Nowadays the design constructional process is almost exclusively aided with CAD/CAE/CAM systems. It is evaluated that nearly 80% of design activities have a routine nature. These design routine tasks are highly susceptible to automation. Design automation is usually made with API tools which allow building original software responsible for adding different engineering activities. In this paper the original software worked out in order to automate engineering tasks at the stage of a product geometrical shape design is presented. The elaborated software works exclusively in NX Siemens CAD/CAM/CAE environment and was prepared in Microsoft Visual Studio with application of the .NET technology and NX SNAP library. The software functionality allows designing and modelling of spur and helicoidal involute gears. Moreover, it is possible to estimate relative manufacturing costs. With the Generator module it is possible to design and model both standard and non-standard gear wheels. The main advantage of the model generated in such a way is its better representation of an involute curve in comparison to those which are drawn in specialized standard CAD systems tools. It comes from fact that usually in CAD systems an involute curve is drawn by 3 points that respond to points located on the addendum circle, the reference diameter of a gear and the base circle respectively. In the Generator module the involute curve is drawn by 11 involute points which are located on and upper the base and the addendum circles therefore 3D gear wheels models are highly accurate. Application of the Generator module makes the modelling process very rapid so that the gear wheel modelling time is reduced to several seconds. During the conducted research the analysis of differences between standard 3 points and 11 points involutes was made. The results and conclusions drawn upon analysis are shown in details.

Three-Dimensional Computational Fluid Dynamics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haworth, D.C.; O'Rourke, P.J.; Ranganathan, R.

1998-09-01

Computational fluid dynamics (CFD) is one discipline falling under the broad heading of computer-aided engineering (CAE). CAE, together with computer-aided design (CAD) and computer-aided manufacturing (CAM), comprise a mathematical-based approach to engineering product and process design, analysis and fabrication. In this overview of CFD for the design engineer, our purposes are three-fold: (1) to define the scope of CFD and motivate its utility for engineering, (2) to provide a basic technical foundation for CFD, and (3) to convey how CFD is incorporated into engineering product and process design.

Integrated design optimization research and development in an industrial environment

NASA Astrophysics Data System (ADS)

Kumar, V.; German, Marjorie D.; Lee, S.-J.

1989-04-01

An overview is given of a design optimization project that is in progress at the GE Research and Development Center for the past few years. The objective of this project is to develop a methodology and a software system for design automation and optimization of structural/mechanical components and systems. The effort focuses on research and development issues and also on optimization applications that can be related to real-life industrial design problems. The overall technical approach is based on integration of numerical optimization techniques, finite element methods, CAE and software engineering, and artificial intelligence/expert systems (AI/ES) concepts. The role of each of these engineering technologies in the development of a unified design methodology is illustrated. A software system DESIGN-OPT has been developed for both size and shape optimization of structural components subjected to static as well as dynamic loadings. By integrating this software with an automatic mesh generator, a geometric modeler and an attribute specification computer code, a software module SHAPE-OPT has been developed for shape optimization. Details of these software packages together with their applications to some 2- and 3-dimensional design problems are described.

Integrated design optimization research and development in an industrial environment

NASA Technical Reports Server (NTRS)

Kumar, V.; German, Marjorie D.; Lee, S.-J.

1989-01-01

An overview is given of a design optimization project that is in progress at the GE Research and Development Center for the past few years. The objective of this project is to develop a methodology and a software system for design automation and optimization of structural/mechanical components and systems. The effort focuses on research and development issues and also on optimization applications that can be related to real-life industrial design problems. The overall technical approach is based on integration of numerical optimization techniques, finite element methods, CAE and software engineering, and artificial intelligence/expert systems (AI/ES) concepts. The role of each of these engineering technologies in the development of a unified design methodology is illustrated. A software system DESIGN-OPT has been developed for both size and shape optimization of structural components subjected to static as well as dynamic loadings. By integrating this software with an automatic mesh generator, a geometric modeler and an attribute specification computer code, a software module SHAPE-OPT has been developed for shape optimization. Details of these software packages together with their applications to some 2- and 3-dimensional design problems are described.

Performance evaluation of the NASA/KSC CAD/CAE and office automation LAN's

NASA Technical Reports Server (NTRS)

Zobrist, George W.

1994-01-01

This study's objective is the performance evaluation of the existing CAD/CAE (Computer Aided Design/Computer Aided Engineering) network at NASA/KSC. This evaluation also includes a similar study of the Office Automation network, since it is being planned to integrate this network into the CAD/CAE network. The Microsoft mail facility which is presently on the CAD/CAE network was monitored to determine its present usage. This performance evaluation of the various networks will aid the NASA/KSC network managers in planning for the integration of future workload requirements into the CAD/CAE network and determining the effectiveness of the planned FDDI (Fiber Distributed Data Interface) migration.

Upstream Design and 1D-CAE

NASA Astrophysics Data System (ADS)

Sawada, Hiroyuki

Recently, engineering design environment of Japan is changing variously. Manufacturing companies are being challenged to design and bring out products that meet the diverse demands of customers and are competitive against those produced by rising countries(1). In order to keep and strengthen the competitiveness of Japanese companies, it is necessary to create new added values as well as conventional ones. It is well known that design at the early stages has a great influence on the final design solution. Therefore, design support tools for the upstream design is necessary for creating new added values. We have established a research society for 1D-CAE (1 Dimensional Computer Aided Engineering)(2), which is a general term for idea, methodology and tools applicable for the upstream design support, and discuss the concept and definition of 1D-CAE. This paper reports our discussion about 1D-CAE.

STEP: What Is It and Should It Be Used for KSC's ISE/CEE Project in the Near Future?

NASA Technical Reports Server (NTRS)

Bareiss, Catherine C.

2000-01-01

The ability to exchange information between different engineering software (i.e, CAD, CAE, CAM) is necessary to aid in collaborative engineering. There are a number of different ways to accomplish this goal. One popular method is to transfer data via different file formats. However this method can lose data and becomes complex as more file formats are added. Another method is to use a standard protocol. STEP is one such standard. This paper gives an overview of STEP, provides a list of where to access more information, and develops guidelines to aid the reader in deciding if STEP is appropriate for his/her use.

Introduction and Highlights of the Workshop

NASA Technical Reports Server (NTRS)

Noor, Ahmed K.; Venneri, Samuel L.

1997-01-01

Four generations of CAD/CAM systems can be identified, corresponding to changes in both modeling functionality and software architecture. The systems evolved from 2D and wireframes to solid modeling, to parametric/variational modelers to the current simulation-embedded systems. Recent developments have enabled design engineers to perform many of the complex analysis tasks, typically performed by analysis experts. Some of the characteristics of the current and emerging CAD/CAM/CAE systems are described in subsequent presentations. The focus of the workshop is on the potential of CAD/CAM/CAE systems for use in simulating the entire mission and life-cycle of future aerospace systems, and the needed development to realize this potential. First, the major features of the emerging computing, communication and networking environment are outlined; second, the characteristics and design drivers of future aerospace systems are identified; third, the concept of intelligent synthesis environment being planned by NASA, the UVA ACT Center and JPL is presented; and fourth, the objectives and format of the workshop are outlined.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goodson, J.O.

This is the first of three volumes which document the historical development of the first US compressed-air energy storage (CAES) Power-generation facility. Volume 1 is a background report and presents a chronicle of the development of the CAES facility from the early interest in CAES until inception of engineering/construction on August 11, 1988. The 110 MW - 26 hr CAES plant is owned and operated by Alabama Electric Cooperative, Inc. (AEC) of Andalusia, Alabama. The plant is the first CAES plant in the United States and the world's first CAES facility incorporating a recuperator to improve efficiency. The plant suppliesmore » competitively priced peaking power to the AEC owner members. The economics of CAES-produced power is attractive because the energy-intensive air-compression mode is powered by relatively inexpensive base-load power external to the CAES plant. The compressed-air energy is stored underground until needed, and during the power-production mode, the only fuel required is that to heat the compressed air to expander-inlet temperature. The project development for AEC's CAES plant involved much planning and preliminary design work. Specifically, this included load and generation-planning studies, power-supply selections, conceptual designs, project administration, air-storage cavern and turbomachinery specifications and design, contract requirements, environmental and licensing issues, and construction planning.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goodson, J.O.

This is the first of three volumes which document the historical development of the first US compressed-air energy storage (CAES) Power-generation facility. Volume 1 is a background report and presents a chronicle of the development of the CAES facility from the early interest in CAES until inception of engineering/construction on August 11, 1988. The 110 MW - 26 hr CAES plant is owned and operated by Alabama Electric Cooperative, Inc. (AEC) of Andalusia, Alabama. The plant is the first CAES plant in the United States and the world`s first CAES facility incorporating a recuperator to improve efficiency. The plant suppliesmore » competitively priced peaking power to the AEC owner members. The economics of CAES-produced power is attractive because the energy-intensive air-compression mode is powered by relatively inexpensive base-load power external to the CAES plant. The compressed-air energy is stored underground until needed, and during the power-production mode, the only fuel required is that to heat the compressed air to expander-inlet temperature. The project development for AEC`s CAES plant involved much planning and preliminary design work. Specifically, this included load and generation-planning studies, power-supply selections, conceptual designs, project administration, air-storage cavern and turbomachinery specifications and design, contract requirements, environmental and licensing issues, and construction planning.« less

Effective Materials Property Information Management for the 21st Century

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ren, Weiju; Cebon, David; Arnold, Steve

2010-01-01

This paper discusses key principles for the development of materials property information management software systems. There are growing needs for automated materials information management in industry, research organizations and government agencies. In part these are fuelled by the demands for higher efficiency in material testing, product design and development and engineering analysis. But equally important, organizations are being driven to employ sophisticated methods and software tools for managing their mission-critical materials information by the needs for consistency, quality and traceability of data, as well as control of access to proprietary or sensitive information. Furthermore the use of increasingly sophisticated nonlinear,more » anisotropic and multi-scale engineering analysis approaches, particularly for composite materials, requires both processing of much larger volumes of test data for development of constitutive models and much more complex materials data input requirements for Computer-Aided Engineering (CAE) software. And finally, the globalization of engineering processes and outsourcing of design and development activities generates much greater needs for sharing a single gold source of materials information between members of global engineering teams in extended supply-chains. Fortunately material property management systems have kept pace with the growing user demands. They have evolved from hard copy archives, through simple electronic databases, to versatile data management systems that can be customized to specific user needs. The more sophisticated of these provide facilities for: (i) data management functions such as access control, version control, and quality control; (ii) a wide range of data import, export and analysis capabilities; (iii) mechanisms for ensuring that all data is traceable to its pedigree sources: details of testing programs, published sources, etc; (iv) tools for searching, reporting and viewing the data; and (v) access to the information via a wide range of interfaces, including web browsers, rich clients, programmatic access and clients embedded in third-party applications, such as CAE systems. This paper discusses the important requirements for advanced material data management systems as well as the future challenges and opportunities such as automated error checking, automated data quality assessment and characterization, identification of gaps in data, as well as functionalities and business models to keep users returning to the source: to generate user demand to fuel database growth and maintenance.« less

CAD/CAE-technologies application for assessment of passenger safety on railway transport in emergency

NASA Astrophysics Data System (ADS)

Antipin, D. Ya; Shorokhov, S. G.; Bondarenko, O. I.

2018-03-01

A possibility of using current software products realizing CAD/CAE-technologies for the assessment of passenger safety in emergency cases on railway transport has been analyzed. On the basis of the developed solid computer model of an anthropometric dummy, the authors carried out an analysis of possible levels of passenger injury during accident collision of a train with an obstacle.

Army-NASA aircrew/aircraft integration program (A3I) software detailed design document, phase 3

NASA Technical Reports Server (NTRS)

Banda, Carolyn; Chiu, Alex; Helms, Gretchen; Hsieh, Tehming; Lui, Andrew; Murray, Jerry; Shankar, Renuka

1990-01-01

The capabilities and design approach of the MIDAS (Man-machine Integration Design and Analysis System) computer-aided engineering (CAE) workstation under development by the Army-NASA Aircrew/Aircraft Integration Program is detailed. This workstation uses graphic, symbolic, and numeric prototyping tools and human performance models as part of an integrated design/analysis environment for crewstation human engineering. Developed incrementally, the requirements and design for Phase 3 (Dec. 1987 to Jun. 1989) are described. Software tools/models developed or significantly modified during this phase included: an interactive 3-D graphic cockpit design editor; multiple-perspective graphic views to observe simulation scenarios; symbolic methods to model the mission decomposition, equipment functions, pilot tasking and loading, as well as control the simulation; a 3-D dynamic anthropometric model; an intermachine communications package; and a training assessment component. These components were successfully used during Phase 3 to demonstrate the complex interactions and human engineering findings involved with a proposed cockpit communications design change in a simulated AH-64A Apache helicopter/mission that maps to empirical data from a similar study and AH-1 Cobra flight test.

Productivity increase through implementation of CAD/CAE workstation

NASA Technical Reports Server (NTRS)

Bromley, L. K.

1985-01-01

The tracking and communication division computer aided design/computer aided engineering system is now operational. The system is utilized in an effort to automate certain tasks that were previously performed manually. These tasks include detailed test configuration diagrams of systems under certification test in the ESTL, floorplan layouts of future planned laboratory reconfigurations, and other graphical documentation of division activities. The significant time savings achieved with this CAD/CAE system are examined: (1) input of drawings and diagrams; (2) editing of initial drawings; (3) accessibility of the data; and (4) added versatility. It is shown that the Applicon CAD/CAE system, with its ease of input and editing, the accessibility of data, and its added versatility, has made more efficient many of the necessary but often time-consuming tasks associated with engineering design and testing.

CAES (conventional compressed-air energy storage) plant with steam generation: Preliminary design and cost analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nakhamkin, M.; Swensen, E.C.; Abitante, P.A.

1990-10-01

A study was performed to evaluate the performance and cost characteristics of two alternative CAES-plant concepts which utilize the low-pressure expander's exhaust-gas heat for the generation of steam in a heat recovery steam generator (HRSG). Both concepts result in increased net-power generation relative to a conventional CAES plant with a recuperator. The HRSG-generated steam produces additional power in either a separate steam-turbine bottoming cycle (CAESCC) or by direct injection into and expansion through the CAES-turboexpander train (CAESSI). The HRSG, which is a proven component of combined-cycle and cogeneration plants, replaces the recuperator of a conventional CAES plant, which has demonstratedmore » the potential for engineering and operating related problems and higher costs than were originally estimated. To enhance the credibility of the results, the analyses performed were based on the performance, operational and cost data of the 110-MW CAES plant currently under construction for the Alabama Electric Cooperative (AEC). The results indicate that CAESCC- and CAESSI-plant concepts are attractive alternatives to the conventional CAES plant with recuperator, providing greater power generation, up to 44-MW relative to the AEC CAES plant, with competitive operating and capital costs. 5 refs., 43 figs., 26 tabs.« less

Computer-aided-engineering system for modeling and analysis of ECLSS integration testing

NASA Technical Reports Server (NTRS)

Sepahban, Sonbol

1987-01-01

The accurate modeling and analysis of two-phase fluid networks found in environmental control and life support systems is presently undertaken by computer-aided engineering (CAE) techniques whose generalized fluid dynamics package can solve arbitrary flow networks. The CAE system for integrated test bed modeling and analysis will also furnish interfaces and subsystem/test-article mathematical models. Three-dimensional diagrams of the test bed are generated by the system after performing the requisite simulation and analysis.

Seneca Compressed Air Energy Storage (CAES) Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2012-11-30

Compressed Air Energy Storage (CAES) is a hybrid energy storage and generation concept that has many potential benefits especially in a location with increasing percentages of intermittent wind energy generation. The objectives of the NYSEG Seneca CAES Project included: for Phase 1, development of a Front End Engineering Design for a 130MW to 210 MW utility-owned facility including capital costs; project financials based on the engineering design and forecasts of energy market revenues; design of the salt cavern to be used for air storage; draft environmental permit filings; and draft NYISO interconnection filing; for Phase 2, objectives included plant constructionmore » with a target in-service date of mid-2016; and for Phase 3, objectives included commercial demonstration, testing, and two-years of performance reporting. This Final Report is presented now at the end of Phase 1 because NYSEG has concluded that the economics of the project are not favorable for development in the current economic environment in New York State. The proposed site is located in NYSEG’s service territory in the Town of Reading, New York, at the southern end of Seneca Lake, in New York State’s Finger Lakes region. The landowner of the proposed site is Inergy, a company that owns the salt solution mining facility at this property. Inergy would have developed a new air storage cavern facility to be designed for NYSEG specifically for the Seneca CAES project. A large volume, natural gas storage facility owned and operated by Inergy is also located near this site and would have provided a source of high pressure pipeline quality natural gas for use in the CAES plant. The site has an electrical take-away capability of 210 MW via two NYSEG 115 kV circuits located approximately one half mile from the plant site. Cooling tower make-up water would have been supplied from Seneca Lake. NYSEG’s engineering consultant WorleyParsons Group thoroughly evaluated three CAES designs and concluded that any of the designs would perform acceptably. Their general scope of work included development of detailed project construction schedules, capital cost and cash flow estimates for both CAES cycles, and development of detailed operational data, including fuel and compression energy requirements, to support dispatch modeling for the CAES cycles. The Dispatch Modeling Consultant selected for this project was Customized Energy Solutions (CES). Their general scope of work included development of wholesale electric and gas market price forecasts and development of a dispatch model specific to CAES technologies. Parsons Brinkerhoff Energy Storage Services (PBESS) was retained to develop an air storage cavern and well system design for the CAES project. Their general scope of work included development of a cavern design, solution mining plan, and air production well design, cost, and schedule estimates for the project. Detailed Front End Engineering Design (FEED) during Phase 1 of the project determined that CAES plant capital equipment costs were much greater than the $125.6- million originally estimated by EPRI for the project. The initial air storage cavern Design Basis was increased from a single five million cubic foot capacity cavern to three, five million cubic foot caverns with associated air production wells and piping. The result of this change in storage cavern Design Basis increased project capital costs significantly. In addition, the development time required to complete the three cavern system was estimated at approximately six years. This meant that the CAES plant would initially go into service with only one third of the required storage capacity and would not achieve full capability until after approximately five years of commercial operation. The market price forecasting and dispatch modeling completed by CES indicated that the CAES technologies would operate at only 10 to 20% capacity factors and the resulting overall project economics were not favorable for further development. As a result of all of these factors, the Phase 1 FEED developed an installed CAES plant cost estimate of approximately $2,300/KW for the 210MW CAES 1A and 2 cycles. The capital cost for the 136 MW CAES 1 cycle was even higher due to the lower generating capacity of the cycle. Notably, the large equipment could have generated additional capacity (up to 270MW) which would have improved the cost per KW; however, the output was limited by the night time transmission system capability. The research herein, therefore, is particular to the site-specific factors that influenced the design and the current and forecasted generation mix and energy prices in Upstate New York and may not necessarily indicate that CAES plants cannot be economically constructed in other places in New York State or the world.« less

Utilization of CAD/CAE for concurrent design of structural aircraft components

NASA Technical Reports Server (NTRS)

Kahn, William C.

1993-01-01

The feasibility of installing the Stratospheric Observatory for Infrared Astronomy telescope (named SOFIA) into an aircraft for NASA astronomy studies is investigated using CAD/CAE equipment to either design or supply data for every facet of design engineering. The aircraft selected for the platform was a Boeing 747, chosen on the basis of its ability to meet the flight profiles required for the given mission and payload. CAD models of the fuselage of two of the aircraft models studied (747-200 and 747 SP) were developed, and models for the component parts of the telescope and subsystems were developed by the various concurrent engineering groups of the SOFIA program, to determine the requirements for the cavity opening and for design configuration. It is noted that, by developing a plan to use CAD/CAE for concurrent engineering at the beginning of the study, it was possible to produce results in about two-thirds of the time required using traditional methods.

Development of life prediction capabilities for liquid propellant rocket engines. Post-fire diagnostic system for the SSME system architecture study

NASA Technical Reports Server (NTRS)

Gage, Mark; Dehoff, Ronald

1991-01-01

This system architecture task (1) analyzed the current process used to make an assessment of engine and component health after each test or flight firing of an SSME, (2) developed an approach and a specific set of objectives and requirements for automated diagnostics during post fire health assessment, and (3) listed and described the software applications required to implement this system. The diagnostic system described is a distributed system with a database management system to store diagnostic information and test data, a CAE package for visual data analysis and preparation of plots of hot-fire data, a set of procedural applications for routine anomaly detection, and an expert system for the advanced anomaly detection and evaluation.

CAE "FOCUS" for modelling and simulating electron optics systems: development and application

NASA Astrophysics Data System (ADS)

Trubitsyn, Andrey; Grachev, Evgeny; Gurov, Victor; Bochkov, Ilya; Bochkov, Victor

2017-02-01

Electron optics is a theoretical base of scientific instrument engineering. Mathematical simulation of occurring processes is a base for contemporary design of complicated devices of the electron optics. Problems of the numerical mathematical simulation are effectively solved by CAE system means. CAE "FOCUS" developed by the authors includes fast and accurate methods: boundary element method (BEM) for the electric field calculation, Runge-Kutta- Fieghlberg method for the charged particle trajectory computation controlling an accuracy of calculations, original methods for search of terms for the angular and time-of-flight focusing. CAE "FOCUS" is organized as a collection of modules each of which solves an independent (sub) task. A range of physical and analytical devices, in particular a microfocus X-ray tube of high power, has been developed using this soft.

The environment power system analysis tool development program

NASA Technical Reports Server (NTRS)

Jongeward, Gary A.; Kuharski, Robert A.; Kennedy, Eric M.; Stevens, N. John; Putnam, Rand M.; Roche, James C.; Wilcox, Katherine G.

1990-01-01

The Environment Power System Analysis Tool (EPSAT) is being developed to provide space power system design engineers with an analysis tool for determining system performance of power systems in both naturally occurring and self-induced environments. The program is producing an easy to use computer aided engineering (CAE) tool general enough to provide a vehicle for technology transfer from space scientists and engineers to power system design engineers. The results of the project after two years of a three year development program are given. The EPSAT approach separates the CAE tool into three distinct functional units: a modern user interface to present information, a data dictionary interpreter to coordinate analysis; and a data base for storing system designs and results of analysis.

Techno-economic assessment of the need for bulk energy storage in low-carbon electricity systems with a focus on compressed air storage (CAES)

NASA Astrophysics Data System (ADS)

Safaei Mohamadabadi, Hossein

Increasing electrification of the economy while decarbonizing the electricity supply is among the most effective strategies for cutting greenhouse gas (GHG) emissions in order to abate climate change. This thesis offers insights into the role of bulk energy storage (BES) systems to cut GHG emissions from the electricity sector. Wind and solar energies can supply large volumes of low-carbon electricity. Nevertheless, large penetration of these resources poses serious reliability concerns to the grid, mainly because of their intermittency. This thesis evaluates the performance of BES systems - especially compressed air energy storage (CAES) technology - for integration of wind energy from engineering and economic aspects. Analytical thermodynamic analysis of Distributed CAES (D-CAES) and Adiabatic CAES (A-CAES) suggest high roundtrip storage efficiencies ( 80% and 70%) compared to conventional CAES ( 50%). Using hydrogen to fuel CAES plants - instead of natural gas - yields a low overall efficiency ( 35%), despite its negligible GHG emissions. The techno-economic study of D-CAES shows that exporting compression heat to low-temperature loads (e.g. space heating) can enhance both the economic and emissions performance of compressed air storage plants. A case study for Alberta, Canada reveals that the abatement cost of replacing a conventional CAES with D-CAES plant practicing electricity arbitrage can be negative (-$40 per tCO2e, when the heat load is 50 km away from the air storage site). A green-field simulation finds that reducing the capital cost of BES - even drastically below current levels - does not substantially impact the cost of low-carbon electricity. At a 70% reduction in the GHG emissions intensity of the grid, gas turbines remain three times more cost-efficient in managing the wind variability compared to BES (in the best case and with a 15-minute resolution). Wind and solar thus, do not need to wait for availability of cheap BES systems to cost-effectively decarbonize the grid. The prospects of A-CAES seem to be stronger compared to other BES systems due to its low energy-specific capital cost.

Designing an Orthotic Insole by Using Kinect® XBOX Gaming Sensor Scanner and Computer Aided Engineering Software

NASA Astrophysics Data System (ADS)

Hafiz Burhan, Mohd; Nor, Nik Hisyamudin Muhd; Yarwindran, Mogan; Ibrahim, Mustaffa; Fahrul Hassan, Mohd; Azwir Azlan, Mohd; Turan, Faiz Mohd; Johan, Kartina

2017-08-01

Healthcare and medical is one of the most expensive field in the modern world. In order to fulfil medical requirement, this study aimed to design an orthotic insole by using Kinect Xbox Gaming Sensor Scanner and CAE softwares. The accuracy of the Kinect® XBOX 360 gaming sensor is capable of producing 3D reconstructed geometry with the maximum and minimum error of 3.78% (2.78mm) and 1.74% (0.46mm) respectively. The orthotic insole design process had been done by using Autodesk Meshmixer 2.6 and Solidworks 2014 software. Functionality of the orthotic insole designed was capable of reducing foot pressure especially in the metatarsal area. Overall, the proposed method was proved to be highly potential in the design of the insole where it promises low cost, less time consuming, and efficiency in regards that the Kinect® XBOX 360 device promised low price compared to other digital 3D scanner since the software needed to run the device can be downloaded for free.

Increasing productivity of the McAuto CAD/CAE system by user-specific applications programming

NASA Technical Reports Server (NTRS)

Plotrowski, S. M.; Vu, T. H.

1985-01-01

Significant improvements in the productivity of the McAuto Computer-Aided Design/Computer-Aided Engineering (CAD/CAE) system were achieved by applications programming using the system's own Graphics Interactive Programming language (GRIP) and the interface capabilities with the main computer on which the system resides. The GRIP programs for creating springs, bar charts, finite element model representations and aiding management planning are presented as examples.

Micromechanics-Based Structural Analysis (FEAMAC) and Multiscale Visualization within Abaqus/CAE Environment

NASA Technical Reports Server (NTRS)

Arnold, Steven M.; Bednarcyk, Brett A.; Hussain, Aquila; Katiyar, Vivek

2010-01-01

A unified framework is presented that enables coupled multiscale analysis of composite structures and associated graphical pre- and postprocessing within the Abaqus/CAE environment. The recently developed, free, Finite Element Analysis--Micromechanics Analysis Code (FEAMAC) software couples NASA's Micromechanics Analysis Code with Generalized Method of Cells (MAC/GMC) with Abaqus/Standard and Abaqus/Explicit to perform micromechanics based FEA such that the nonlinear composite material response at each integration point is modeled at each increment by MAC/GMC. The Graphical User Interfaces (FEAMAC-Pre and FEAMAC-Post), developed through collaboration between SIMULIA Erie and the NASA Glenn Research Center, enable users to employ a new FEAMAC module within Abaqus/CAE that provides access to the composite microscale. FEA IAC-Pre is used to define and store constituent material properties, set-up and store composite repeating unit cells, and assign composite materials as sections with all data being stored within the CAE database. Likewise FEAMAC-Post enables multiscale field quantity visualization (contour plots, X-Y plots), with point and click access to the microscale i.e., fiber and matrix fields).

Executive control systems in the engineering design environment. M.S. Thesis

NASA Technical Reports Server (NTRS)

Hurst, P. W.

1985-01-01

An executive control system (ECS) is a software structure for unifying various applications codes into a comprehensive system. It provides a library of applications, a uniform access method through a cental user interface, and a data management facility. A survey of twenty-four executive control systems designed to unify various CAD/CAE applications for use in diverse engineering design environments within government and industry was conducted. The goals of this research were to establish system requirements to survey state-of-the-art architectural design approaches, and to provide an overview of the historical evolution of these systems. Foundations for design are presented and include environmental settings, system requirements, major architectural components, and a system classification scheme based on knowledge of the supported engineering domain(s). An overview of the design approaches used in developing the major architectural components of an ECS is presented with examples taken from the surveyed systems. Attention is drawn to four major areas of ECS development: interdisciplinary usage; standardization; knowledge utilization; and computer science technology transfer.

75 FR 11917 - Chrysler LLC, Technology Center, Including On-Site Leased Workers from Aerotek, Ajilon, Altair...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-12

..., Cer-Cad Engineering Resources, Computer Consultants of America, Computer Engrg Services, Compuware..., Automated Analysis Corp/Belcan, Bartech Group, CAE Tech, CDI Information Services, CER-CAD Engineering...

Large space antennas: A systems analysis case history

NASA Technical Reports Server (NTRS)

Keafer, Lloyd S. (Compiler); Lovelace, U. M. (Compiler)

1987-01-01

The value of systems analysis and engineering is aptly demonstrated by the work on Large Space Antennas (LSA) by the NASA Langley Spacecraft Analysis Branch. This work was accomplished over the last half-decade by augmenting traditional system engineering, analysis, and design techniques with computer-aided engineering (CAE) techniques using the Langley-developed Interactive Design and Evaluation of Advanced Spacecraft (IDEAS) system. This report chronicles the research highlights and special systems analyses that focused the LSA work on deployable truss antennas. It notes developmental trends toward greater use of CAE techniques in their design and analysis. A look to the future envisions the application of improved systems analysis capabilities to advanced space systems such as an advanced space station or to lunar and Martian missions and human habitats.

Enhancing Engineering Computer-Aided Design Education Using Lectures Recorded on the PC

ERIC Educational Resources Information Center

McGrann, Roy T. R.

2006-01-01

Computer-Aided Engineering (CAE) is a course that is required during the third year in the mechanical engineering curriculum at Binghamton University. The primary objective of the course is to educate students in the procedures of computer-aided engineering design. The solid modeling and analysis program Pro/Engineer[TM] (PTC[R]) is used as the…

A SINDA thermal model using CAD/CAE technologies

NASA Technical Reports Server (NTRS)

Rodriguez, Jose A.; Spencer, Steve

1992-01-01

The approach to thermal analysis described by this paper is a technique that incorporates Computer Aided Design (CAD) and Computer Aided Engineering (CAE) to develop a thermal model that has the advantages of Finite Element Methods (FEM) without abandoning the unique advantages of Finite Difference Methods (FDM) in the analysis of thermal systems. The incorporation of existing CAD geometry, the powerful use of a pre and post processor and the ability to do interdisciplinary analysis, will be described.

Automated knowledge base development from CAD/CAE databases

NASA Technical Reports Server (NTRS)

Wright, R. Glenn; Blanchard, Mary

1988-01-01

Knowledge base development requires a substantial investment in time, money, and resources in order to capture the knowledge and information necessary for anything other than trivial applications. This paper addresses a means to integrate the design and knowledge base development process through automated knowledge base development from CAD/CAE databases and files. Benefits of this approach include the development of a more efficient means of knowledge engineering, resulting in the timely creation of large knowledge based systems that are inherently free of error.

LAMPAT and LAMPATNL User’s Manual

DTIC Science & Technology

2012-09-01

nonlinearity. These tools are implemented as subroutines in the finite element software ABAQUS . This user’s manual provides information on the proper...model either through the General tab of the Edit Job dialog box in Abaqus /CAE or the command line with user=( subroutine filename). Table 1...Selection of software product and subroutine . Static Analysis With Abaqus /Standard Dynamic Analysis With Abaqus /Explicit Linear, uncoupled

Computer aided system engineering for space construction

NASA Technical Reports Server (NTRS)

Racheli, Ugo

1989-01-01

This viewgraph presentation covers the following topics. Construction activities envisioned for the assembly of large platforms in space (as well as interplanetary spacecraft and bases on extraterrestrial surfaces) require computational tools that exceed the capability of conventional construction management programs. The Center for Space Construction is investigating the requirements for new computational tools and, at the same time, suggesting the expansion of graduate and undergraduate curricula to include proficiency in Computer Aided Engineering (CAE) though design courses and individual or team projects in advanced space systems design. In the center's research, special emphasis is placed on problems of constructability and of the interruptability of planned activity sequences to be carried out by crews operating under hostile environmental conditions. The departure point for the planned work is the acquisition of the MCAE I-DEAS software, developed by the Structural Dynamics Research Corporation (SDRC), and its expansion to the level of capability denoted by the acronym IDEAS**2 currently used for configuration maintenance on Space Station Freedom. In addition to improving proficiency in the use of I-DEAS and IDEAS**2, it is contemplated that new software modules will be developed to expand the architecture of IDEAS**2. Such modules will deal with those analyses that require the integration of a space platform's configuration with a breakdown of planned construction activities and with a failure modes analysis to support computer aided system engineering (CASE) applied to space construction.

Analysis of the Hexapod Work Space using integration of a CAD/CAE system and the LabVIEW software

NASA Astrophysics Data System (ADS)

Herbuś, K.; Ociepka, P.

2015-11-01

The paper presents the problems related to the integration of a CAD/CAE system with the LabVIEW software. The purpose of the integration is to determine the workspace of a hexapod model basing on a mathematical model describing it motion. In the first stage of the work concerning the integration task the 3D model to simulate movements of a hexapod was elaborated. This phase of the work was done in the “Motion Simulation” module of the CAD/CAE/CAM Siemens NX system. The first step was to define the components of the 3D model in the form of “links”. Individual links were defined according to the nature of the hexapod elements action. In the model prepared for movement simulation were created links corresponding to such elements as: electric actuator, top plate, bottom plate, ball-and-socket joint, toggle joint Phillips. Then were defined the constraints of the “joint” type (e.g.: revolute joint, slider joint, spherical joint) between the created component of the “link” type, so that the computer simulation corresponds to the operation of a real hexapod. The next stage of work included implementing the mathematical model describing the functioning of a hexapod in the LabVIEW software. At this stage, particular attention was paid to determining procedures for integrating the virtual 3D hexapod model with the results of calculations performed in the LabVIEW. The results relate to specific values of the jump of electric actuators depending on the position of the car on the hexapod. The use of integration made it possible to determine the safe operating space of a stationary hexapod taking into consideration the security of a person in the driving simulator designed for the disabled.

Creating three-dimensional tooth models from tomographic images.

PubMed

Lima da Silva, Isaac Newton; Barbosa, Gustavo Frainer; Soares, Rodrigo Borowski Grecco; Beltrao, Maria Cecilia Gomes; Spohr, Ana Maria; Mota, Eduardo Golcalves; Oshima, Hugo Mitsuo Silva; Burnett, Luiz Henrique

2008-01-01

The use of Finite Element Analysis (FEA) is becoming very frequent in Dentistry. However, most of the three-dimensional models presented by the literature for teeth are limited in terms of geometry. Discrepancy in shape and dimensions can cause wrong results to occur. Sharp cusps and faceted contour can produce stress concentrations, which are incoherent with the reality. The aim of this study was the processing of tomographic images in order to develop an advanced three-dimensional reconstruction of the anatomy of a molar tooth and the integration of the resulting solid with commercially available CAD/CAE software. Computed tomographic images were obtained from 0.5 mm thick slices of mandibular molar and transferred to commercial cad software. Once the point cloud data have been generated, the work on these points started to get to the solid model of the tooth with Pro/Engineer software. The obtained tooth model showed very accurate shape and dimensions, as it was obtained from real tooth data with error of 0.0 to -0.8 mm. The methodology presented was efficient for creating a biomodel of a tooth from tomographic images that realistically represented its anatomy.

I-deas TMG to NX Space Systems Thermal Model Conversion and Computational Performance Comparison

NASA Technical Reports Server (NTRS)

Somawardhana, Ruwan

2011-01-01

CAD/CAE packages change on a continuous basis as the power of the tools increase to meet demands. End -users must adapt to new products as they come to market and replace legacy packages. CAE modeling has continued to evolve and is constantly becoming more detailed and complex. Though this comes at the cost of increased computing requirements Parallel processing coupled with appropriate hardware can minimize computation time. Users of Maya Thermal Model Generator (TMG) are faced with transitioning from NX I -deas to NX Space Systems Thermal (SST). It is important to understand what differences there are when changing software packages We are looking for consistency in results.

Defense Acquisitions Acronyms and Terms

DTIC Science & Technology

2012-12-01

Computer-Aided Design CADD Computer-Aided Design and Drafting CAE Component Acquisition Executive; Computer-Aided Engineering CAIV Cost As an...Radiation to Ordnance HFE Human Factors Engineering HHA Health Hazard Assessment HNA Host-Nation Approval HNS Host-Nation Support HOL High -Order...Engineering Change Proposal VHSIC Very High Speed Integrated Circuit VLSI Very Large Scale Integration VOC Volatile Organic Compound W WAN Wide

Evolutions of Advanced Stamping CAE — Technology Adventures and Business Impact on Automotive Dies and Stamping

NASA Astrophysics Data System (ADS)

Wang, Chuantao (C. T.)

2005-08-01

In the past decade, sheet metal forming and die development has been transformed to a science-based and technology-driven engineering and manufacturing enterprise from a tryout-based craft. Stamping CAE, especially the sheet metal forming simulation, as one of the core components in digital die making and digital stamping, has played a key role in this historical transition. The stamping simulation technology and its industrial applications have greatly impacted automotive sheet metal product design, die developments, die construction and tryout, and production stamping. The stamping CAE community has successfully resolved the traditional formability problems such as splits and wrinkles. The evolution of the stamping CAE technology and business demands opens even greater opportunities and challenges to stamping CAE community in the areas of (1) continuously improving simulation accuracy, drastically reducing simulation time-in-system, and improving operationalability (friendliness), (2) resolving those historically difficult-to-resolve problems such as dimensional quality problems (springback and twist) and surface quality problems (distortion and skid/impact lines), (3) resolving total manufacturability problems in line die operations including blanking, draw/redraw, trim/piercing, and flanging, and (4) overcoming new problems in forming new sheet materials with new forming techniques. In this article, the author first provides an overview of the stamping CAE technology adventures and achievements, and industrial applications in the past decade. Then the author presents a summary of increasing manufacturability needs from the formability to total quality and total manufacturability of sheet metal stampings. Finally, the paper outlines the new needs and trends for continuous improvements and innovations to meet increasing challenges in line die formability and quality requirements in automotive stamping.

NASA Tech Briefs, March 1999. Volume 23, No. 3

NASA Technical Reports Server (NTRS)

1999-01-01

Topics include: special coverage sections on CAD/CAE/PDM, industrial controls and sections on electronic components systems, materials, software, mechanics, machinery/automation, manufacturing/fabrication, physical sciences, book and reports, and a special section of Photonics Tech Briefs and a seconds special section of Rapid Product Development.

Coupled Mechanical-Electrochemical-Thermal Modeling for Accelerated Design of EV Batteries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Santhanagopalan, Shriram; Zhang, Chao; Kim, Gi-Heon

2015-05-03

This presentation provides an overview of the mechanical electrochemical-thermal (M-ECT) modeling efforts. The physical phenomena occurring in a battery are many and complex and operate at different scales (particle, electrodes, cell, and pack). A better understanding of the interplay between different physics occurring at different scales through modeling could provide insight to design improved batteries for electric vehicles. Work funded by the U.S. DOE has resulted in development of computer-aided engineering (CAE) tools to accelerate electrochemical and thermal design of batteries; mechanical modeling is under way. Three competitive CAE tools are now commercially available.

Data management for Computer-Aided Engineering (CAE)

NASA Technical Reports Server (NTRS)

Bryant, W. A.; Smith, M. R.

1984-01-01

Analysis of data flow through the design and manufacturing processes has established specific information management requirements and identified unique problems. The application of data management technology to the engineering/manufacturing environment addresses these problems. An overview of the IPAD prototype data base management system, representing a partial solution to these problems, is presented here.

Effective Materials Property Information Management for the 21st Century

NASA Technical Reports Server (NTRS)

Ren, Weiju; Cebon, David; Arnold, Steve

2009-01-01

This paper discusses key principles for the development of materials property information management software systems. There are growing needs for automated materials information management in various organizations. In part these are fueled by the demands for higher efficiency in material testing, product design and engineering analysis. But equally important, organizations are being driven by the need for consistency, quality and traceability of data, as well as control of access to sensitive information such as proprietary data. Further, the use of increasingly sophisticated nonlinear, anisotropic and multi-scale engineering analyses requires both processing of large volumes of test data for development of constitutive models and complex materials data input for Computer-Aided Engineering (CAE) software. And finally, the globalization of economy often generates great needs for sharing a single "gold source" of materials information between members of global engineering teams in extended supply chains. Fortunately, material property management systems have kept pace with the growing user demands and evolved to versatile data management systems that can be customized to specific user needs. The more sophisticated of these provide facilities for: (i) data management functions such as access, version, and quality controls; (ii) a wide range of data import, export and analysis capabilities; (iii) data "pedigree" traceability mechanisms; (iv) data searching, reporting and viewing tools; and (v) access to the information via a wide range of interfaces. In this paper the important requirements for advanced material data management systems, future challenges and opportunities such as automated error checking, data quality characterization, identification of gaps in datasets, as well as functionalities and business models to fuel database growth and maintenance are discussed.

NASA Tech Briefs, October 2000. Volume 24, No. 10

NASA Technical Reports Server (NTRS)

2000-01-01

Topics include: special coverage sections on CAD, CAE, and PDM, and, Composites and Plastics, and sections on electronic components and systems, software, test and measurement, mechanics, manufacturing/fabrication, physical sciences, information sciences, book and reports, and special sections of Electronics Tech Briefs and Motion Control Tech Briefs

Improved simulation method of automotive spot weld failure with an account of the mechanical properties of spot welds

NASA Astrophysics Data System (ADS)

Wu, H.; Meng, X. M.; Fang, R.; Huang, Y. F.; Zhan, S.

2017-12-01

In this paper, the microstructure and mechanical properties of spot weld were studied, the hardness of nugget and heat affected zone (HAZ) were also tested by metallographic microscope and microhardness tester. The strength of the spot weld with the different parts' area has been characterized. According to the experiments result, CAE model of spot weld with HAZ structure was established, and simulation results of different lap-shear CAE models were analyzed. The results show that the spot weld model which contained the HAZ has good performance and more suitable for engineering application in spot weld simulation.

NASA/ASEE Summer Faculty Fellowship Program

NASA Technical Reports Server (NTRS)

Hosler, E. Ramon (Editor); Armstrong, Dennis W. (Editor)

1989-01-01

The contractor's report contains all sixteen final reports prepared by the participants in the 1989 Summer Faculty Fellowship Program. Reports describe research projects on a number of different topics. Interface software, metal corrosion, rocket triggering lightning, automatic drawing, 60-Hertz power, carotid-cardiac baroreflex, acoustic fields, robotics, AI, CAD/CAE, cryogenics, titanium, and flow measurement are discussed.

Phosphatidyl inositol-3 kinase (PIK3CA) E545K mutation confers cisplatin resistance and a migratory phenotype in cervical cancer cells.

PubMed

Arjumand, Wani; Merry, Cole D; Wang, Chen; Saba, Elias; McIntyre, John B; Fang, Shujuan; Kornaga, Elizabeth; Ghatage, Prafull; Doll, Corinne M; Lees-Miller, Susan P

2016-12-13

The phosphatidylinositol-3 kinase (PI3K)/Akt/mTOR signaling pathway is activated in many human cancers. Previously, we reported that patients with early stage cervical cancer whose tumours harbour PIK3CA exon 9 or 20 mutations have worse overall survival in response to treatment with radiation and cisplatin than patients with wild-type PIK3CA. The purpose of this study was to determine whether PIK3CA-E545K mutation renders cervical cancer cells more resistant to cisplatin and/or radiation, and whether PI3K inhibition reverses the phenotype. We found that CaSki cells that are heterozygous for the PIK3CA-E545K mutation are more resistant to cisplatin or cisplatin plus radiation than either HeLa or SiHa cells that express only wild-type PIK3CA. Similarly, HeLa cells engineered to stably express PIK3CA-E545K were more resistant to cisplatin or cisplatin plus radiation than cells expressing only wild-type PIK3CA or with PIK3CA depleted. Cells expressing the PIK3CA-E545K mutation also had constitutive PI3K pathway activation and increased cellular migration and each of these phenotypes was reversed by treatment with the PI3K inhibitor GDC-0941/Pictilisib. Our results suggests that cervical cancer patients whose tumours are positive for the PIK3CA-E545K mutation may benefit from PI3K inhibitor therapy in concert with standard cisplatin and radiation therapy.

Emerging CAE technologies and their role in Future Ambient Intelligence Environments

NASA Astrophysics Data System (ADS)

Noor, Ahmed K.

2011-03-01

Dramatic improvements are on the horizon in Computer Aided Engineering (CAE) and various simulation technologies. The improvements are due, in part, to the developments in a number of leading-edge technologies and their synergistic combinations/convergence. The technologies include ubiquitous, cloud, and petascale computing; ultra high-bandwidth networks, pervasive wireless communication; knowledge based engineering; networked immersive virtual environments and virtual worlds; novel human-computer interfaces; and powerful game engines and facilities. This paper describes the frontiers and emerging simulation technologies, and their role in the future virtual product creation and learning/training environments. The environments will be ambient intelligence environments, incorporating a synergistic combination of novel agent-supported visual simulations (with cognitive learning and understanding abilities); immersive 3D virtual world facilities; development chain management systems and facilities (incorporating a synergistic combination of intelligent engineering and management tools); nontraditional methods; intelligent, multimodal and human-like interfaces; and mobile wireless devices. The Virtual product creation environment will significantly enhance the productivity and will stimulate creativity and innovation in future global virtual collaborative enterprises. The facilities in the learning/training environment will provide timely, engaging, personalized/collaborative and tailored visual learning.

Effective Materials Property Information Management for the 21st Century

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ren, Weiju; Cebon, David; Barabash, Oleg M

2011-01-01

This paper discusses key principles for the development of materials property information management software systems. There are growing needs for automated materials information management in various organizations. In part these are fuelled by the demands for higher efficiency in material testing, product design and engineering analysis. But equally important, organizations are being driven by the needs for consistency, quality and traceability of data, as well as control of access to proprietary or sensitive information. Further, the use of increasingly sophisticated nonlinear, anisotropic and multi-scale engineering analyses requires both processing of large volumes of test data for development of constitutive modelsmore » and complex materials data input for Computer-Aided Engineering (CAE) software. And finally, the globalization of economy often generates great needs for sharing a single gold source of materials information between members of global engineering teams in extended supply-chains. Fortunately material property management systems have kept pace with the growing user demands and evolved to versatile data management systems that can be customized to specific user needs. The more sophisticated of these provide facilities for: (i) data management functions such as access, version, and quality controls; (ii) a wide range of data import, export and analysis capabilities; (iii) data pedigree traceability mechanisms; (iv) data searching, reporting and viewing tools; and (v) access to the information via a wide range of interfaces. In this paper the important requirements for advanced material data management systems, future challenges and opportunities such as automated error checking, data quality characterization, identification of gaps in datasets, as well as functionalities and business models to fuel database growth and maintenance are discussed.« less

Silicon Wafer Advanced Packaging (SWAP). Multichip Module (MCM) Foundry Study. Version 2

DTIC Science & Technology

1991-04-08

Next Layer Dielectric Spacing - Additional Metal Thickness Impact on Dielectric Uniformity/Adhiesion. The first step in .!Ie EPerimental design would be... design CAM - computer aided manufacturing CAE - computer aided engineering CALCE - computer aided life cycle engineering center CARMA - computer aided...expansion 5 j- CVD - chemical vapor deposition J . ..- j DA - design automation J , DEC - Digital Equipment Corporation --- DFT - design for testability

Predator-prey modeling of the coupling of co-propagating CAE to kink modes

NASA Astrophysics Data System (ADS)

Fredrickson, Eric

2012-10-01

Co-propagating Compressional Alfven eigenmodes (CAE) with shorter wavelength and higher frequency than the counter-propagating CAE and Global Alfven eigenmodes (GAE) often accompany a low frequency n=1 kink. The lower frequency CAE and GAE are excited through a Doppler-shifted cyclotron resonance; the high frequency CAE (hfCAE) through a simple parallel resonance. We present measurements of the mode structure and spectrum of the hfCAE, and compare those measurements to predictions of a simple model for CAE. The modes are bursting with a typical burst frequency on the order of a few kHz. The n=1 kink frequency is usually higher than this, but when the kink frequency does drop towards the hfCAE burst frequency, the hfCAE burst frequency can become locked with the kink frequency. A simple predator-prey model to simulate the hfCAE bursting demonstrates that a modulation of the growth or damping rate by a few percent, at a frequency near the natural burst frequency, can lock the burst frequency to the modulation frequency. The modulation of the damping rate is postulated to be through a coupling of the kink with a symmetry-breaking error field. The deeper question is how the kink interaction with a locked mode can affect the damping/growth rates of the CAE.

The application of CAD, CAE & CAM in development of butterfly valve’s disc

NASA Astrophysics Data System (ADS)

Asiff Razif Shah Ranjit, Muhammad; Hanie Abdullah, Nazlin

2017-06-01

The improved design of a butterfly valve disc is based on the concept of sandwich theory. Butterfly valves are mostly used in various industries such as oil and gas plant. The primary failure modes for valves are indented disc, keyways and shaft failure and the cavitation damage. Emphasis on the application of CAD, a new model of the butterfly valve’s disc structure was designed. The structure analysis was analysed using the finite element analysis. Butterfly valve performance factors can be obtained is by using Computational Fluid Dynamics (CFD) software to simulate the physics of fluid flow in a piping system around a butterfly valve. A comparison analysis was done using the finite element to justify the performance of the structure. The second application of CAE is the computational fluid flow analysis. The upstream pressure and the downstream pressure was analysed to calculate the cavitation index and determine the performance throughout each opening position of the valve. The CAM process was done using 3D printer to produce a prototype and analysed the structure in form of prototype. The structure was downscale fabricated based on the model designed initially through the application of CAD. This study is utilized the application of CAD, CAE and CAM for a better improvement of the butterfly valve’s disc components.

Computer-Aided Engineering (CAE) Tool Assessment/Development

DTIC Science & Technology

1990-09-01

ionized, generating glow as well as acting as a plasma source.(see below) The code SOCRATES (Shuttle Orbiter Contamination Representation Accounting...DRIVE SAN JOSE , CA 95129-0000 SUE MCMURRAY LOCKHEED MISSLES & SPACE CO. BLDG. 157, DEPT. 81-63 11 LOCKHEED WAY SUNNYVALE, CA 94089-3504 K.D. MELLOT NASA

Design and development of a quad copter (UMAASK) using CAD/CAM/CAE

NASA Astrophysics Data System (ADS)

Manarvi, Irfan Anjum; Aqib, Muhammad; Ajmal, Muhammad; Usman, Muhammad; Khurshid, Saqib; Sikandar, Usman

Micro flying vehicles1 (MFV) have become a popular area of research due to economy of production, flexibility of launch and variety of applications. A large number of techniques from pencil sketching to computer based software are being used for designing specific geometries and selection of materials to arrive at novel designs for specific requirements. Present research was focused on development of suitable design configuration using CAD/CAM/CAE tools and techniques. A number of designs were reviewed for this purpose. Finally, rotary wing Quadcopter flying vehicle design was considered appropriate for this research. Performance requirements were planned as approximately 10 meters ceiling, weight less than 500grams and ability to take videos and pictures. Parts were designed using Finite Element Analysis, manufactured using CNC machines and assembled to arrive at final design named as UMAASK. Flight tests were carried out which confirmed the design requirements.

Caerulomycin A Suppresses Immunity by Inhibiting T Cell Activity

PubMed Central

Chauhan, Arun; Khatri, Neeraj; Vohra, Rakesh M.; Jolly, Ravinder S.; Agrewala, Javed N.

2014-01-01

Background Caerulomycin A (CaeA) is a known antifungal and antibiotic agent. Further, CaeA is reported to induce the expansion of regulatory T cell and prolongs the survival of skin allografts in mouse model of transplantation. In the current study, CaeA was purified and characterized from a novel species of actinomycetes, Actinoalloteichus spitiensis. The CaeA was identified for its novel immunosuppressive property by inhibiting in vitro and in vivo function of T cells. Methods Isolation, purification and characterization of CaeA were performed using High Performance Flash Chromatography (HPFC), NMR and mass spectrometry techniques. In vitro and in vivo T cell studies were conducted in mice using flowcytometry, ELISA and thymidine-[methyl-3H] incorporation. Results CaeA significantly suppressed T cell activation and IFN-γ secretion. Further, it inhibited the T cells function at G1 phase of cell cycle. No apoptosis was noticed by CaeA at a concentration responsible for inducing T cell retardation. Furthermore, the change in the function of B cells but not macrophages was observed. The CaeA as well exhibited substantial inhibitory activity in vivo. Conclusion This study describes for the first time novel in vitro and in vivo immunosuppressive function of CaeA on T cells and B cells. CaeA has enough potential to act as a future immunosuppressive drug. PMID:25286329

The IDEAS**2 computing environment

NASA Technical Reports Server (NTRS)

Racheli, Ugo

1990-01-01

This document presents block diagrams of the IDEAS**2 computing environment. IDEAS**2 is the computing environment selected for system engineering (design and analysis) by the Center for Space Construction (CSC) at the University of Colorado (UCB). It is intended to support integration and analysis of any engineering system and at any level of development, from Pre-Phase A conceptual studies to fully mature Phase C/D projects. The University of Colorado (through the Center for Space Construction) has joined the Structural Dynamics Research Corporation (SDRC) University Consortium which makes available unlimited software licenses for instructional purposes. In addition to providing the backbone for the implementation of the IDEAS**2 computing environment, I-DEAS can be used as a stand-alone product for undergraduate CAD/CAE instruction. Presently, SDRC is in the process of releasing I-DEAS level 5.0 which represents a substantial improvement in both the user interface and graphic processing capabilities. IDEAS**2 will be immediately useful for a number of current programs within CSC (such as DYCAM and the 'interruptability problem'). In the future, the following expansions of the basic IDEAS**2 program will be pursued, consistent with the overall objectives of the Center and of the College: upgrade I-DEAS and IDEAS**2 to level 5.0; create new analytical programs for applications not limited to orbital platforms; research the semantic organization of engineering databases; and create an 'interoperability' testbed.

Computer Design Technology of the Small Thrust Rocket Engines Using CAE / CAD Systems

NASA Astrophysics Data System (ADS)

Ryzhkov, V.; Lapshin, E.

2018-01-01

The paper presents an algorithm for designing liquid small thrust rocket engine, the process of which consists of five aggregated stages with feedback. Three stages of the algorithm provide engineering support for design, and two stages - the actual engine design. A distinctive feature of the proposed approach is a deep study of the main technical solutions at the stage of engineering analysis and interaction with the created knowledge (data) base, which accelerates the process and provides enhanced design quality. The using multifunctional graphic package Siemens NX allows to obtain the final product -rocket engine and a set of design documentation in a fairly short time; the engine design does not require a long experimental development.

The value of compressed air energy storage in energy and reserve markets

DOE PAGES

Drury, Easan; Denholm, Paul; Sioshansi, Ramteen

2011-06-28

Storage devices can provide several grid services, however it is challenging to quantify the value of providing several services and to optimally allocate storage resources to maximize value. We develop a co-optimized Compressed Air Energy Storage (CAES) dispatch model to characterize the value of providing operating reserves in addition to energy arbitrage in several U.S. markets. We use the model to: (1) quantify the added value of providing operating reserves in addition to energy arbitrage; (2) evaluate the dynamic nature of optimally allocating storage resources into energy and reserve markets; and (3) quantify the sensitivity of CAES net revenues tomore » several design and performance parameters. We find that conventional CAES systems could earn an additional 23 ± 10/kW-yr by providing operating reserves, and adiabatic CAES systems could earn an additional 28 ± 13/kW-yr. We find that arbitrage-only revenues are unlikely to support a CAES investment in most market locations, but the addition of reserve revenues could support a conventional CAES investment in several markets. Adiabatic CAES revenues are not likely to support an investment in most regions studied. As a result, modifying CAES design and performance parameters primarily impacts arbitrage revenues, and optimizing CAES design will be nearly independent of dispatch strategy.« less

Protective effects of a polymethoxy flavonoids-rich Citrus aurantium peel extract on liver fibrosis induced by bile duct ligation in mice.

PubMed

Lim, Seol-Wa; Lee, Dong-Ryung; Choi, Bong-Keun; Kim, Hong-Suk; Yang, Seung Hwan; Suh, Joo-Won; Kim, Kyung Soo

2016-12-01

To evaluate the possible protective effect of Citrus aurantium peel extract (CAE) against apoptosis in cholestatic liver fibrosis induced by bile duct ligation in mice. Male ICR mice were divided to 5 groups: 1) Control group (Sham-operated mice), 2) Cholestatic liver injury group induced by bile duct ligation (BDL), 3) BDL mice treated with silymarin (200 mg/kg) for 4 weeks, 4) BDL mice treated with 50 mg/kg CAE for 4 weeks, 5) BDL mice treated with 200 mg/kg CAE for 4 weeks. Mice were sacrificed and liver fibrosis was evaluated by serum and hepatic tissue biochemistry tests and liver histopathological examination. Effects of CAE on inflammation and apoptosis gene regulation were investigated through real-time PCR. CAE effect on lipid metabolism related signaling was determined by western blot analysis. In BDL mice, administration of CAE for 4 weeks markedly attenuated liver fibrosis based on histopathological alteration. Serum and hepatic tissue biochemistry results revealed that CAE (50 and 200 mg/kg) decreased the levels of alanine transaminase, aspartate transaminase, gamma-glutamyl transferase, total bilirubin, nitric oxide, and thiobarbituric acid reactive substances. Real-time PCR and western blot analysis showed that CAE regulated inflammation, apoptosis, and lipid metabolism factors increased by BDL. Interleukin family, tumor necrosis factor α, and related apoptosis factors mRNA levels were increased by BDL treatment. However, these increases were suppressed by CAE administration. In addition, CAE effectively increased phosphorylation of AMP-activated protein kinase, nuclear factor E2-related factor 2, and related cytoprotective proteins. CAE can efficiently regulate BDL-induced liver injury with antioxidant, anti-inflammatory, and anti-apoptotic activities. Copyright © 2016 Hainan Medical University. Production and hosting by Elsevier B.V. All rights reserved.

Information Infrastructures for Integrated Enterprises

DTIC Science & Technology

1993-05-01

PROCESSING demographic CAM realization; ule leveling; studies; prelimi- rapid tooling; con- accounting/admin- nary CAFE and tinuous cost istrative reports...nies might consider franchising some facets of indirect labor, such as selected functions of administration, finance, and human resources. Incorporate as...vices CAFE Corporate Average Fuel Economy CAD Computer-Aided Design 0 CAE Computer-Aided Engineering CAIS Common Ada Programming Support Environment

Peer Review of “LDT Weight Reduction Study with Crash Model, Feasibility and Detailed Cost Analyses – Chevrolet Silverado 1500 Pickup”

EPA Science Inventory

The contractor will conduct an independent peer review of FEV’s light-duty truck (LDT) mass safety study, “Light-Duty Vehicle Weight Reduction Study with Crash Model, Feasibility and Detailed Cost Analysis – Silverado 1500”, and its corresponding computer-aided engineering (CAE) ...

Alleviation of Ultraviolet B-Induced Photodamage by Coffea arabica Extract in Human Skin Fibroblasts and Hairless Mouse Skin

PubMed Central

Wu, Po-Yuan; Huang, Chi-Chang; Chu, Yin; Huang, Ya-Han; Lin, Ping; Liu, Yu-Han; Wen, Kuo-Ching; Lin, Chien-Yih; Hsu, Mei-Chich; Chiang, Hsiu-Mei

2017-01-01

Coffea arabica extract (CAE) containing 48.3 ± 0.4 mg/g of chlorogenic acid and a trace amount of caffeic acid was found to alleviate photoaging activity in human skin fibroblasts. In this study, polyphenol-rich CAE was investigated for its antioxidant and antiinflammatory properties, as well as for its capability to alleviate ultraviolet B (UVB)-induced photodamage in BALB/c hairless mice. The results indicated that 500 μg/mL of CAE exhibited a reducing power of 94.7%, ferrous ion chelating activity of 46.4%, and hydroxyl radical scavenging activity of 20.3%. The CAE dose dependently reduced UVB-induced reactive oxygen species (ROS) generation in fibroblasts. Furthermore, CAE inhibited the UVB-induced expression of cyclooxygenase-2 and p-inhibitor κB, and the translocation of nuclear factor-kappa B (NF-κB) to the nucleus of fibroblasts. In addition, CAE alleviated UVB-induced photoaging and photodamage in BALB/c hairless mice by restoring the collagen content and reduced UVB-induced epidermal hyperplasia. CAE also inhibited UVB-induced NF-κB, interleukin-6, and matrix metalloproteinase-1 expression in the hairless mouse skin. The results indicated that CAE exhibits antiphotodamage activity by inhibiting UV-induced oxidative stress and inflammation. Therefore, CAE is a candidate for use in antioxidant, antiinflammatory, and antiphotodamage products. PMID:28387707

Creating a Community of Practice: Lessons Learned from the Center for Astronomy Education (Invited)

NASA Astrophysics Data System (ADS)

Brissenden, G.

2009-12-01

The Center for Astronomy Education (CAE) is devoted to improving teaching and learning in Astro 101. To accomplish this, a vital part of CAE is our broader community of practice which includes over 1000 instructors, graduate and undergraduate students, and postdocs. It is this greater community of practice that supports each other, helps, and learns from each other beyond what would be possible without it. As our community of practice has grown, we at CAE have learned many lessons about how different facets of CAE can best be used to promote and support our community both as a whole and for individual members. We will discuss the various facets of CAE, such as our online discussion group Astrolrner@CAE (http://astronomy101.jpl.nasa.gov/discussion) and its Guest Moderator program, our CAE Regional Teaching Exchange Coordinator program, our CAE Workshop Presenter Apprenticeship Training program, our online This Month’s Teaching Strategy, monthly newsletters, and various types of socializing and networking sessions we hold at national meetings. But more importantly, we will discuss the lessons we’ve learned about what does and does not work in building community within each of these facets.

Investigation of IGES for CAD/CAE data transfer

NASA Technical Reports Server (NTRS)

Zobrist, George W.

1989-01-01

In a CAD/CAE facility there is always the possibility that one may want to transfer the design graphics database from the native system to a non-native system. This may occur because of dissimilar systems within an organization or a new CAD/CAE system is to be purchased. The Initial Graphics Exchange Specification (IGES) was developed in an attempt to solve this scenario. IGES is a neutral database format into which the CAD/CAE native database format can be translated to and from. Translating the native design database format to IGES requires a pre-processor and transling from IGES to the native database format requires a post-processor. IGES is an artifice to represent CAD/CAE product data in a neutral environment to allow interfacing applications, archive the database, interchange of product data between dissimilar CAD/CAE systems, and other applications. The intent here is to present test data on translating design product data from a CAD/CAE system to itself and to translate data initially prepared in IGES format to various native design formats. This information can be utilized in planning potential procurement and developing a design discipline within the CAD/CAE community.

Cap-assisted endoscopic sclerotherapy for hemorrhoids: Methods, feasibility and efficacy

PubMed Central

Zhang, Ting; Xu, Li-Juan; Xiang, Jie; He, Zhi; Peng, Zhao-Yuan; Huang, Guang-Ming; Ji, Guo-Zhong; Zhang, Fa-Ming

2015-01-01

AIM: To evaluate the methodology, feasibility, safety and efficacy of a novel method called cap-assisted endoscopic sclerotherapy (CAES) for internal hemorrhoids. METHODS: A pilot study on CAES for grade I to III internal hemorrhoids was performed. Colon and terminal ileum examination by colonoscopy was performed for all patients before starting CAES. Polypectomy and excision of anal papilla fibroma were performed if polyps or anal papilla fibroma were found and assessed to be suitable for resection under endoscopy. CAES was performed based on the requirement of the cap, endoscope, disposable endoscopic long injection needle, enough insufflated air and sclerosing agent. RESULTS: A total of 30 patients with grade I to III internal hemorrhoids was included. The follow-up was more than four weeks. No bleeding was observed after CAES. One (3.33%) patient claimed mild tenesmus within four days after CAES in that an endoscopist performed this procedure for the first time. One hundred percent of patients were satisfied with this novel procedure, especially for those patients who underwent CAES in conjunction with polypectomy or excision of anal papilla fibroma. CONCLUSION: CAES as a novel endoscopic sclerotherapy should be a convenient, safe and effective flexible endoscopic therapy for internal hemorrhoids. PMID:26722615

Compressed-air energy storage: Commercialization potential and EPRI roles in the commercialization process

NASA Astrophysics Data System (ADS)

Boyd, D. W.; Buckley, O. E.; Clark, C. E.

1982-12-01

This report describes an assessment of potential roles that EPRI might take to facilitate the commercial acceptance of compressed air energy storage (CAES) systems. The assessment is based on (1) detailed analyses of the market potential of utility storage technologies, (2) interviews with representatives of key participants in the CAES market, and (3) a decision analysis synthesizing much of the information about market and technology status. The results indicate a large potential market for CAES systems if the overall business environment for utilities improves. In addition, it appears that EPRI can have a valuable incremental impact in ensuring that utilities realize the potential of CAES by (1) continuing an aggressive information dissemination and technology transfer program, (2) working to ensure the success of the first United States CAES installation at Soyland Power Cooperative, (3) developing planning methods to allow utilities to evaluate CAES and other storage options more effectively and more realistically, and (4) supporting R and D to resolve residual uncertainties in first-generation CAES cost and performance characteristics.

Application Of Moldex3D For Thin-wall Injection Moulding Simulation

NASA Astrophysics Data System (ADS)

Šercer, Mladen; Godec, Damir; Bujanić, Božo

2007-05-01

The benefits associated with decreasing wall thicknesses below their current values are still measurable and desired even if the final wall thickness is nowhere near those of the aggressive portable electronics industry. It is important to note that gains in wall section reduction do not always occur without investment, in this case, in tooling and machinery upgrades. Equally important is the fact that productivity and performance benefits of reduced material usage, fast cycle times, and lighter weight can often outweigh most of the added costs. In order to eliminate unnecessary mould trials, minimize product development cycle, reduce overall costs and improve product quality, polymeric engineers use new CAE technology (Computer Aided Engineering). This technology is a simulation tool, which combines proven theories, material properties and process conditions to generate realistic simulations and produce valuable recommendations. Based on these recommendations, an optional combination of product design, material and process conditions can be identified. In this work, Moldex3D software was used for simulation of injection moulding in order to avoid potential moulding problems. The results gained from the simulation were used for the optimization of an existing product design, for mould development and for optimization of processing parameters, e.g. injection pressure, mould cavity temperature, etc.

Cutaneous adverse events during treatment of chronic inflammatory rheumatic conditions with tumor necrosis factor antagonists: study using the Spanish registry of adverse events of biological therapies in rheumatic diseases.

PubMed

Hernández, M Victoria; Sanmartí, Raimon; Cañete, Juan D; Descalzo, Miguel A; Alsina, Mercè; Carmona, Loreto; Gomez-Reino, Juan J

2013-12-01

To analyze the incidence rate (IR) and risk factors of cutaneous adverse events (CAE) in patients with chronic inflammatory rheumatic diseases treated with tumor necrosis factor (TNF) antagonists. We analyzed all patients from the BIOBADASER (Base de Datos de Productos Biológicos de la Sociedad Española de Reumatología) registry treated with a TNF antagonist (infliximab, etanercept, or adalimumab). Data collected included age, sex, diagnosis and duration of rheumatic disease, type of TNF antagonist, and concomitant treatment. Type of CAE was classified as local or systemic cutaneous manifestation related to treatment administration (infusion reaction), infection, malignancy, or autoimmune skin disease. Time of onset of CAE and outcome were also recorded. The IRs of CAE per 1,000 patient-years of exposure with 95% confidence intervals (95% CIs) were estimated. Multivariable analysis was performed to identify potential risk factors for CAE. A total of 5,437 patients were included, representing 17,330 patient-years of exposure. A total of 920 CAE were reported; the IRs per 1,000 patient-years were 53 (95% CI 50-57) for CAE, 28 (95% CI 25-30) for infection, 15 (95% CI 13-17) for infusion reactions, 5 (95% CI 4-6) for autoimmune skin diseases, and 3 (95% CI 2-4) for skin malignancy. The mean time between starting TNF antagonist treatment and CAE was 1.78 years. In 32% of patients, CAE required TNF antagonist withdrawal. The main risk factors for CAE were female sex and treatment with infliximab, leflunomide, and glucocorticoids. The IR of CAE in patients treated with TNF antagonists is significant and should be addressed carefully, and withdrawal of therapy is required in some cases. Copyright © 2013 by the American College of Rheumatology.

Toxicological analysis and antihyperalgesic, antidepressant, and anti-inflammatory effects of Campomanesia adamantium fruit barks.

PubMed

de Souza, Juliane C; Piccinelli, Ana Cláudia; Aquino, Diana F S; de Souza, Vanessa V; Schmitz, Wanderlei O; Traesel, Giseli K; Cardoso, Claudia A L; Kassuya, Candida A L; Arena, Arielle C

2017-01-01

This study evaluates the anti-inflammatory, antihyperalgesic, and antidepressive potential of the hydroalcoholic extract of Campomanesia adamantium fruit barks (CAE) on rodents and determines the safety of this plant. The acute toxicity of CAE was evaluated by oral administration to female rats as single doses of 0, 500, 1000, or 2000 mg/kg body weight. General behavior and toxic symptoms were observed for 14 days. In the subacute toxicity test, male and female rats received 125 or 250 mg/kg body weight of CAE for 28 days. The oral anti-inflammatory activity of CAE was evaluated in carrageenan-induced pleurisy in male mice. The effect of treatment with CAE (100 mg/kg) for 15 days was evaluated in mechanical hyperalgesia (electronic von Frey), depressive behavior (forced swimming test), and cold hypersensitivity in spared nerve injury (SNI) model in rats. No clinical signs of toxicity were observed in animals from the experimental groups during acute and subacute exposure to CAE. At pleurisy test, the oral administration of CAE significantly inhibited leukocyte migration and protein leakage at all doses tested when compared to control. Oral administration of CAE for 3-15 days significantly inhibited SNI-induced mechanical hyperalgesia and increased immobility in the forced swim test. Finally, on the 15th day, oral treatment with CAE prevented the increase in sensitivity to a cold stimulus induced by SNI. The present study shows that C. adamantium extract has anti-inflammatory, antihyperalgesic, and antidepressive properties in rodents without causing toxicity.

The Value of Competitive Contracting

DTIC Science & Technology

2014-09-01

Research & Engineering) BBP Better Buying Power BOA basic ordering agreement BPA basic purchase agreement CAE Component Acquisition Executive CDSA...competitive procedures for the following contract actions:” a. Contract and purchase orders b. Orders and calls under part 13 Basic Purchase Agreement ( BPA ...Basic Ordering Agreement (BOA) c. Government wide acquisition contracts and IDIQ contracts d. BPAs and BPA calls under Federal Supply Schedules

The Role of Multipurpose C.A.Es: The Institutional and Staff Perspectives 1974-1975. C.A.T. Education Monograph No. 24.

ERIC Educational Resources Information Center

Davis, D. J.; Hermann, G. D.

The attitudes and ideologies of staff and institutional administrators concerning the role of the multipurpose colleges of advanced education in tertiary education in Australia were investigated. The data for the investigation were gathered using two different questionnaires sent to academic staff in civil and mechanical engineering, architecture…

CAE for Injection Molding — Past, Present and the Future

NASA Astrophysics Data System (ADS)

Wang, Kuo K.

2004-06-01

It is well known that injection molding is the most effective process for mass-producing discrete plastic parts of complex shape to the highest precision at the lowest cost. However, due to the complex property of polymeric materials undergoing a transient non-isothermal process, it is equally well recognized that the quality of final products is often difficult to be assured. This is particularly true when a new mold or material is encountered. As a result, injection molding has often been viewed as an art than a science. During the past few decades, numerical simulation of injection molding process based on analytic models has become feasible for practical use as computers became faster and cheaper continually. A research effort was initiated at the Cornell Injection Molding Program (CIMP) in 1974 under a grant from the National Science Foundation. Over a quarter of the century, CIMP has established some scientific bases ranging from materials characterization, flow analysis, to prediction of part quality. Use of such CAE tools has become common place today in industry. Present effort has been primarily aimed at refinements of many aspects of the process. Computational efficiency and user-interface have been main thrusts by commercial software developers. Extension to 3-dimensional flow analysis for certain parts has drawn some attention. Research activities are continuing on molding of fiber-filled materials and reactive polymers. Expanded molding processes such as gas-assisted, co-injection, micro-molding and many others are continually being investigated. In the future, improvements in simulation accuracy and efficiency will continue. This will include in-depth studies on materials characterization. Intelligent on-line process control may draw more attention in order to achieve higher degree of automation. As Internet technology continues to evolve, Web-based CAE tools for design, production, remote process monitoring and control can come to path. The CAE tools will eventually be integrated into an Enterprise Resources Planning (ERP) system as the trend of enterprise globalization continues.

Towards Automatic Processing of Virtual City Models for Simulations

NASA Astrophysics Data System (ADS)

Piepereit, R.; Schilling, A.; Alam, N.; Wewetzer, M.; Pries, M.; Coors, V.

2016-10-01

Especially in the field of numerical simulations, such as flow and acoustic simulations, the interest in using virtual 3D models to optimize urban systems is increasing. The few instances in which simulations were already carried out in practice have been associated with an extremely high manual and therefore uneconomical effort for the processing of models. Using different ways of capturing models in Geographic Information System (GIS) and Computer Aided Engineering (CAE), increases the already very high complexity of the processing. To obtain virtual 3D models suitable for simulation, we developed a tool for automatic processing with the goal to establish ties between the world of GIS and CAE. In this paper we introduce a way to use Coons surfaces for the automatic processing of building models in LoD2, and investigate ways to simplify LoD3 models in order to reduce unnecessary information for a numerical simulation.

Assessment of market potential of compressed air energy storage systems

NASA Astrophysics Data System (ADS)

Boyd, D. W.; Buckley, O. E.; Clark, C. E., Jr.

1983-12-01

This report describes an assessment of potential roles that EPRI might take to facilitate the commercial acceptance of compressed air energy storage (CAES) systems. The assessment is based on (1) detailed analyses of the market potential of utility storage technologies, (2) interviews with representatives of key participants in the CAES market, and (3) a decision analysis synthesizing much of the information about market and technology status. The results indicate a large potential market for CAES systems if the overall business environment for utilities improves. In addition, it appears that EPRI can have a valuable incremental impact in ensuring that utilities realize the potential of CAES by (1) continuing an aggressive information dissemination and technology transfer program, (2) working to ensure the success of the first United States CAES installation at Soyland Power Cooperative, (3) developing planning methods to allow utilities to evaluate CAES and other storage options more effectively and more realistically, and (4) supporting R and D to resolve residual uncertainties in first-generation CAES cost and performance characteristics. Previously announced in STAR as N83-25121

Amygdala volumes in childhood absence epilepsy.

PubMed

Schreibman Cohen, Ayelet; Daley, Melita; Siddarth, Prabha; Levitt, Jennifer; Loesch, Ingrid K; Altshuler, Lori; Ly, Ronald; Shields, W Donald; Gurbani, Suresh; Caplan, Rochelle

2009-11-01

Abnormal amygdala volumes in pediatric mood-anxiety disorders and attention deficit hyperactivity disorder (ADHD), as well as high rates of these diagnoses in childhood absence epilepsy (CAE), prompted this study of amygdala volume in CAE. Twenty-six children with CAE and 23 normal children, aged 6.6-15.8 years, underwent MRI at 1.5 T. The tissue imaged with MRI was segmented, and amygdala volumes were obtained by manual tracings. There were no significant amygdala volume differences between the CAE and normal groups. Within the CAE group, however, the children with ADHD had significantly smaller amygdala volumes than the subjects with CAE with no psychopathology and those with mood/anxiety diagnoses. There was also a significant relationship between higher seizure frequency and greater amygdala asymmetry in the epilepsy group. Given ongoing development of the amygdala during late childhood and adolescence, despite the lack of significant group differences in amygdala volumes, the association of amygdala volume abnormalities with ADHD and seizure frequency implies a possible impact of the disorder on amygdala development and CAE-associated comorbidities, such as ADHD.

Attention Contributes to Arithmetic Deficits in New-Onset Childhood Absence Epilepsy.

PubMed

Cheng, Dazhi; Yan, Xiuxian; Gao, Zhijie; Xu, Keming; Chen, Qian

2017-01-01

Neuropsychological studies indicate that new-onset childhood absence epilepsy (CAE) is associated with deficits in attention and executive functioning. However, the contribution of these deficits to impaired academic performance remains unclear. We aimed to examine whether attention and executive functioning deficits account for the academic difficulties prevalent in patients with new-onset CAE. We analyzed cognitive performance in several domains, including language, mathematics, psychomotor speed, spatial ability, memory, general intelligence, attention, and executive functioning, in 35 children with new-onset CAE and 33 control participants. Patients with new-onset CAE exhibited deficits in mathematics, general intelligence, attention, and executive functioning. Furthermore, attention deficits, as measured by a visual tracing task, accounted for impaired arithmetic performance in the new-onset CAE group. Therefore, attention deficits, rather than impaired general intelligence or executive functioning, may be responsible for arithmetic performance deficits in patients with new-onset CAE.

Analysis of integrating compressed air energy storage concepts with coal gasification/combined-cycle systems for continuous power production. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nakhamkin, M.; Patel, M.; Andersson, L.

1992-12-01

A previous study sponsored by EPRI concluded that integrating a compressed-air energy storage (CAES) plant with a coal-gasification system (CGS) can reduce the required capacity and cost of the expensive gasification system. The results showed that when compared at an equal plant capacity, the capital cost of the CGS portion of the integrated CAES/CGS plant can be reduced by as much as 30% relative to the same portion of an integrated gasification combined cycle (IGCC) plant. Furthermore, the capital cost of the CAES/CGS.plant, configured as a peaking unit, was found to be slightly lower than that of the base-load IGCCmore » plant. However, the overall economics of the CAES/CGS plant were adversely affected by the low capacity factor of the peak-load service, and ultimately, were found to be less attractive than the IGCC plant. The main objective of this study was to develop and analyze integrated CAES/CGS power plant concepts which provide for continuous (around-the-clock) operation of both the CAES reheat turboexpander train and the CGS facility. The developed concepts also provide utility-load management functions by driving the CAES compressor trains with off-peak electricity supplied through the grid. EPRI contracted with Energy Storage & Power Consultants, Inc. (ESPC) to develop conceptual designs, optimized performance characteristics, and preliminary cost data for these CAES/CGS concepts, and to provide a technical and cost comparison to the IGCC plant. The CAES/CGS concepts developed by ESPC for the current study contrast from those of Reference 1.« less

Analysis of integrating compressed air energy storage concepts with coal gasification/combined-cycle systems for continuous power production

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nakhamkin, M.; Patel, M.; Andersson, L.

1992-12-01

A previous study sponsored by EPRI concluded that integrating a compressed-air energy storage (CAES) plant with a coal-gasification system (CGS) can reduce the required capacity and cost of the expensive gasification system. The results showed that when compared at an equal plant capacity, the capital cost of the CGS portion of the integrated CAES/CGS plant can be reduced by as much as 30% relative to the same portion of an integrated gasification combined cycle (IGCC) plant. Furthermore, the capital cost of the CAES/CGS.plant, configured as a peaking unit, was found to be slightly lower than that of the base-load IGCCmore » plant. However, the overall economics of the CAES/CGS plant were adversely affected by the low capacity factor of the peak-load service, and ultimately, were found to be less attractive than the IGCC plant. The main objective of this study was to develop and analyze integrated CAES/CGS power plant concepts which provide for continuous (around-the-clock) operation of both the CAES reheat turboexpander train and the CGS facility. The developed concepts also provide utility-load management functions by driving the CAES compressor trains with off-peak electricity supplied through the grid. EPRI contracted with Energy Storage Power Consultants, Inc. (ESPC) to develop conceptual designs, optimized performance characteristics, and preliminary cost data for these CAES/CGS concepts, and to provide a technical and cost comparison to the IGCC plant. The CAES/CGS concepts developed by ESPC for the current study contrast from those of Reference 1.« less

A p-coumaroyl esterase from Rhizoctonia solani with a pronounced chlorogenic acid esterase activity.

PubMed

Nieter, Annabel; Kelle, Sebastian; Linke, Diana; Berger, Ralf G

2017-07-25

Extracellular esterase activity was detected in submerged cultures of Rhizoctonia solani grown in the presence of sugar beet pectin or Tween 80. Putative type B feruloyl esterase (FAE) coding sequences found in the genome data of the basidiomycete were heterologously expressed in Pichia pastoris. Recombinant enzyme production on the 5-L bioreactor scale (Rs pCAE: 3245UL -1 ) exceeded the productivity of the wild type strain by a factor of 800. Based on substrate specificity profiling, the purified recombinant Rs pCAE was classified as a p-coumaroyl esterase (pCAE) with a pronounced chlorogenic acid esterase side activity. The Rs pCAE was also active on methyl cinnamate, caffeate and ferulate and on feruloylated saccharides. The unprecedented substrate profile of Rs pCAE together with the lack of sequence similarity to known FAEs or pCAEs suggested that the Rs pCAE represents a new type of enzyme. Hydroxycinnamic acids were released from agro-industrial side-streams, such as destarched wheat bran (DSWB), sugar beet pectin (SBP) and coffee pulp (CP). Overnight incubation of coffee pulp with the Rs pCAE resulted in the efficient release of p-coumaric (100%), caffeic (100%) and ferulic acid (85%) indicating possible applications for the valorization of food processing wastes and for the enhanced degradation of lignified biomass. Copyright © 2017 Elsevier B.V. All rights reserved.

Performance Study of Salt Cavern Air Storage Based Non-Supplementary Fired Compressed Air Energy Storage System

NASA Astrophysics Data System (ADS)

Chen, Xiaotao; Song, Jie; Liang, Lixiao; Si, Yang; Wang, Le; Xue, Xiaodai

2017-10-01

Large-scale energy storage system (ESS) plays an important role in the planning and operation of smart grid and energy internet. Compressed air energy storage (CAES) is one of promising large-scale energy storage techniques. However, the high cost of the storage of compressed air and the low capacity remain to be solved. This paper proposes a novel non-supplementary fired compressed air energy storage system (NSF-CAES) based on salt cavern air storage to address the issues of air storage and the efficiency of CAES. Operating mechanisms of the proposed NSF-CAES are analysed based on thermodynamics principle. Key factors which has impact on the system storage efficiency are thoroughly explored. The energy storage efficiency of the proposed NSF-CAES system can be improved by reducing the maximum working pressure of the salt cavern and improving inlet air pressure of the turbine. Simulation results show that the electric-to-electric conversion efficiency of the proposed NSF-CAES can reach 63.29% with a maximum salt cavern working pressure of 9.5 MPa and 9 MPa inlet air pressure of the turbine, which is higher than the current commercial CAES plants.

Incidence of esophageal cancer in Sri Lanka: Analysis of cancer registry data and comparison with other South Asian populations.

PubMed

Wickramasinghe, Dakshitha P; Samarasekera, Dharmabandhu N

2017-10-01

The objectives of this study were to report the incidence of Carcinoma of Esophagus (CaE) in Sri Lanka and to compare these values with other cancer registry data of the region and with migrant populations. We compared the data published by the National Cancer Control Program over the last two decades with data from the National Cancer Registry Programme of the Indian Council of Medical Research and Karachi Cancer Registry. SEERstat was used to analyze the surveillance, epidemiology and end results database to analyze data on Indian migrant population. CaE was the fourth most common cancer overall and among females and third most common cancer among males. The incidence of CaE rises with age in both sexes, with a peak in the 70-74 year age group. There was a disproportionately higher number of CaE in the Tamil population (chi-square test, P < 0.00001). The commonest type of CaE in Sri Lanka was squamous cell carcinoma, Not otherwise specified (NOS) (n = 750, 70.5%), followed by adenocarcinoma, NOS (n = 83, 7.8%). India, Pakistan and Sri Lanka have comparable age-adjusted incidence and age distribution of CaE. All migrant populations had lower incidence of CaE than original population or population in their present country. Both cigarette smoking and alcohol consumption are more prevalent in Sri Lankan males than females. The incidence of CaE and its distribution among age groups in Sri Lanka was comparable to other countries of the region. Persons of Tamil ethnicity have a higher risk of developing CaE. © 2016 John Wiley & Sons Australia, Ltd.

Coronary artery ectasia, an independent predictor of no-reflow after primary PCI for ST-elevation myocardial infarction.

PubMed

Schram, H C F; Hemradj, V V; Hermanides, R S; Kedhi, E; Ottervanger, J P

2018-04-25

The no-reflow phenomenon is a serious complication after primary percutaneous coronary intervention (PCI) for ST-elevation Myocardial Infarction (STEMI). Coronary artery ectasia (CAE) may increase the risk of no-reflow, however, only limited data is available on the potential impact of CAE. The aim of this study was to determine the potential association between CAE and no-reflow after primary PCI. A case control study was performed based on a prospective cohort of STEMI patients from January 2000 to December 2011. All patients with TIMI 0-1 flow post primary PCI, in the absence of dissection, thrombus, spasm or high-grade residual stenosis, were considered as no-reflow case. Control subjects were two consecutive STEMI patients after each case, with TIMI flow ≥2 after primary PCI. CAE was defined as dilatation of an arterial segment to a diameter at least 1.5 times that of the adjacent normal coronary artery. In the no-reflow group, frequency of CAE was significantly higher (33.8% vs 3.9%, p < 0.001) compared to the control group. Baseline variables were comparable between patients with and without CAE. Patients with CAE had more often TIMI 0-1 flow pre-PCI (91% vs 71% p = 0.03), less often anterior STEMI (3% vs 37%, p < 0.001) and underwent significantly less often a PCI with stenting (47% vs 74%, p = 0.003). After multivariate analysis, CAE remained a strong and independent predictor of no-reflow (OR 13.9, CI 4.7-41.2, p < 0.001). CAE is a strong and independent predictor of no-reflow after primary PCI for STEMI. Future studies should assess optimal treatment. Copyright © 2017 Elsevier B.V. All rights reserved.

NASA Engineering Excellence: A Case Study on Strengthening an Engineering Organization

NASA Technical Reports Server (NTRS)

Shivers, C. Herbert; Wessel, Vernon W.

2006-01-01

NASA implemented a system of technical authority following the Columbia Accident Investigation Board (CAE) report calling for independent technical authority to be exercised on the Space Shuttle Program activities via a virtual organization of personnel exercising specific technical authority responsibilities. After the current NASA Administrator reported for duty, and following the first of two planned "Shuttle Return to Flight" missions, the NASA Chief Engineer and the Administrator redirected the Independent Technical Authority to a program of Technical Excellence and Technical Authority exercised within the existing engineering organizations. This paper discusses the original implementation of technical authority and the transition to the new implementation of technical excellence, including specific measures aimed at improving safety of future Shuttle and space exploration flights.

Experimental evaluation of a translating nozzle sidewall radial turbine

NASA Technical Reports Server (NTRS)

Roelke, Richard J.; Rogo, Casimir

1987-01-01

Studies have shown that reduced specific fuel consumption of rotorcraft engines can be achieved with a variable capacity engine. A key component in such an engine in a high-work, high-temperature variable geometry gas generator turbine. An optimization study indicated that a radial turbine with a translating nozzle sidewall could produce high efficiency over a wide range of engine flows but substantiating data were not available. An experimental program with Teledyne CAE, Toledo, Ohio was undertaken to evaluate the moving sidewall concept. A variety of translating nozzle sidewall turbine configurations were evaluated. The effects of nozzle leakage and coolant flows were also investigated. Testing was done in warm air (121 C). The results of the contractual program were summarized.

Nonlinear simulations of beam-driven Compressional Alfv´en Eigenmodes in NSTX

DOE PAGES

Belova, Elena V.; Gorelenkov, N. N.; Crocker, N. A.; ...

2017-03-10

We present results for the 3D nonlinear simulations of neutral-beam-driven compressional Alfv´en eigenmodes (CAEs) in the National Spherical Torus Experiment (NSTX). Hybrid MHD-particle simulations for the H-mode NSTX discharge (shot 141398) using the HYM code show unstable CAE modes for a range of toroidal mode numbers, n = 4 - 9, and frequencies below the ion cyclotron frequency. It is found that the essential feature of CAEs is their coupling to kinetic Alfv´en wave (KAW) that occurs on the high-field side at the Alfv´en resonance location. We frequently observe high-frequency Alfv´en eigenmodes in beam-heated NSTX plasmas, and have been linkedmore » to flattening of the electron temperature profiles at high beam power. Coupling between CAE and KAW suggests an energy channeling mechanism to explain these observations, in which beam driven CAEs dissipate their energy at the resonance location, therefore significantly modifying the energy deposition profile. Nonlinear simulations demonstrate that CAEs can channel the energy of the beam ions from the injection region near the magnetic axis to the location of the resonant mode conversion at the edge of the beam density profile. Furthermore, a set of nonlinear simulations show that the CAE instability saturates due to nonlinear particle trapping, and a large fraction of beam energy can be transferred to several unstable CAEs of relatively large amplitudes and absorbed at the resonant location. Absorption rate shows a strong scaling with the beam power.« less

Caerulomycin A Enhances Transforming Growth Factor-β (TGF-β)-Smad3 Protein Signaling by Suppressing Interferon-γ (IFN-γ)-Signal Transducer and Activator of Transcription 1 (STAT1) Protein Signaling to Expand Regulatory T Cells (Tregs)*

PubMed Central

Gurram, Rama Krishna; Kujur, Weshely; Maurya, Sudeep K.; Agrewala, Javed N.

2014-01-01

Cytokines play a very important role in the regulation of immune homeostasis. Regulatory T cells (Tregs) responsible for the generation of peripheral tolerance are under the tight regulation of the cytokine milieu. In this study, we report a novel role of a bipyridyl compound, Caerulomycin A (CaeA), in inducing the generation of Tregs. It was observed that CaeA substantially up-regulated the pool of Tregs, as evidenced by an increased frequency of CD4+ Foxp3+ cells. In addition, CaeA significantly suppressed the number of Th1 and Th17 cells, as supported by a decreased percentage of CD4+/IFN-γ+ and CD4+/IL-17+ cells, respectively. Furthermore, we established the mechanism and observed that CaeA interfered with IFN-γ-induced STAT1 signaling by augmenting SOCS1 expression. An increase in the TGF-β-mediated Smad3 activity was also noted. Furthermore, CaeA rescued Tregs from IFN-γ-induced inhibition. These results were corroborated by blocking Smad3 activity, which abolished the CaeA-facilitated generation of Tregs. In essence, our results indicate a novel role of CaeA in inducing the generation of Tregs. This finding suggests that CaeA has enough potential to be considered as a potent future drug for the treatment of autoimmunity. PMID:24811173

Nonlinear simulations of beam-driven Compressional Alfv´en Eigenmodes in NSTX

DOE Office of Scientific and Technical Information (OSTI.GOV)

Belova, Elena V.; Gorelenkov, N. N.; Crocker, N. A.

We present results for the 3D nonlinear simulations of neutral-beam-driven compressional Alfv´en eigenmodes (CAEs) in the National Spherical Torus Experiment (NSTX). Hybrid MHD-particle simulations for the H-mode NSTX discharge (shot 141398) using the HYM code show unstable CAE modes for a range of toroidal mode numbers, n = 4 - 9, and frequencies below the ion cyclotron frequency. It is found that the essential feature of CAEs is their coupling to kinetic Alfv´en wave (KAW) that occurs on the high-field side at the Alfv´en resonance location. We frequently observe high-frequency Alfv´en eigenmodes in beam-heated NSTX plasmas, and have been linkedmore » to flattening of the electron temperature profiles at high beam power. Coupling between CAE and KAW suggests an energy channeling mechanism to explain these observations, in which beam driven CAEs dissipate their energy at the resonance location, therefore significantly modifying the energy deposition profile. Nonlinear simulations demonstrate that CAEs can channel the energy of the beam ions from the injection region near the magnetic axis to the location of the resonant mode conversion at the edge of the beam density profile. Furthermore, a set of nonlinear simulations show that the CAE instability saturates due to nonlinear particle trapping, and a large fraction of beam energy can be transferred to several unstable CAEs of relatively large amplitudes and absorbed at the resonant location. Absorption rate shows a strong scaling with the beam power.« less

A past psychiatric history may be a risk factor for topiramate-related psychiatric and cognitive adverse events.

PubMed

Kanner, Andres M; Wuu, Joanne; Faught, Edward; Tatum, William O; Fix, Aaron; French, Jacqueline A

2003-10-01

Topiramate (TPM) is a new antiepileptic drug (AED) that has been found to be associated with a high prevalence of cognitive adverse events (CAEs). The prevalence of psychiatric adverse events (PAEs) has yet to be established. The purpose of this study was to determine the prevalence of PAEs related to TPM when used in polytherapy regimens in a large cohort of adult patients with epilepsy, to identify any association between the occurrences of CAEs and PAEs and to identify predictors of PAEs and CAEs. Investigators from 16 epilepsy centers (PADS group) prospectively obtained postmarketing safety and efficacy data on 596 patients aged 16 years and older. All data were recorded on standardized data retrieval forms, completed at the initial visit, while follow-up data were obtained every 6 months or at the time of discontinuation. PAEs were identified in 75 (12.6%) patients: 30 (5%) experienced symptoms of depression and 34 (5.7%) of aggressive behavior and irritability, while 9 patients experienced symptoms of psychosis (1.5%). CAEs were reported by 247 (41.5%) patients. There was a significant association between the occurrences of CAEs and PAEs. A past psychiatric history was a predictor of CAEs, while older age and past psychiatric history were predictors of PAEs. The use of TPM in polytherapy regimens can cause PAEs and CAEs and their occurrence is significantly correlated. Patients with a past psychiatric history may be at a higher risk for experiencing PAEs and CAEs.

A Shift in Emphasis: Comments on CAE's New Mission Statement

ERIC Educational Resources Information Center

Anderson-Levitt, Kathryn M.

2007-01-01

In a presidential address prepared for the 2006 Council on Anthropology and Education (CAE) meeting, I argue that the new mission statement for CAE represents not a new direction for the organization, but simply a shift in emphasis, albeit an important and timely shift.

75 FR 9142 - Information Assurance Scholarship Program (IASP)

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-01

... university to NSA. Centers of Academic Excellence in Information Assurance Education (CAE/IAEs) interested in... following terms apply to this part: Center of Academic Excellence (CAE). A collective term that refers to both a National Center of Academic Excellence in Information Assurance Education (CAE/IAE) and a...

ParaView visualization of Abaqus output on the mechanical deformation of complex microstructures

NASA Astrophysics Data System (ADS)

Liu, Qingbin; Li, Jiang; Liu, Jie

2017-02-01

Abaqus® is a popular software suite for finite element analysis. It delivers linear and nonlinear analyses of mechanical and fluid dynamics, includes multi-body system and multi-physics coupling. However, the visualization capability of Abaqus using its CAE module is limited. Models from microtomography have extremely complicated structures, and datasets of Abaqus output are huge, requiring a visualization tool more powerful than Abaqus/CAE. We convert Abaqus output into the XML-based VTK format by developing a Python script and then using ParaView to visualize the results. Such capabilities as volume rendering, tensor glyphs, superior animation and other filters allow ParaView to offer excellent visualizing manifestations. ParaView's parallel visualization makes it possible to visualize very big data. To support full parallel visualization, the Python script achieves data partitioning by reorganizing all nodes, elements and the corresponding results on those nodes and elements. The data partition scheme minimizes data redundancy and works efficiently. Given its good readability and extendibility, the script can be extended to the processing of more different problems in Abaqus. We share the script with Abaqus users on GitHub.

N-alpha-Cocoyl-L-arginine ethyl ester, DL-pyroglutamic acid salt, as an inactivator of hepatitis B surface antigen.

PubMed Central

Sugimoto, Y; Toyoshima, S

1979-01-01

N-alpha-Cocoyl-L-arginine ethyl ester, DL-pyroglutamic acid salt (CAE), exhibited a strong inactivating effect on hepatitis B surface antigen. Concentrations of CAE required for 50 and 100% inactivation of the antigen were 0.01 to 0.025% and 0.025 to 0.05% respectively. CAE completely inactivated hepatitis B surface antigen at the lowest concentration compared with various compounds including about 500 amino acid derivatives, sodium hypochlorite, 2,4,4'-trichloro-2'-hydroxydiphenyl ether, and some detergents. Furthermore, CAE inactivated vaccinia virus, herpes simplex virus, and influenza virus, whereas poliovirus was not inactivated at all. The results suggest that the inactivating effects of CAE are related to interaction with lipid-containing viral envelopes. PMID:228595

Frontal and temporal volumes in Childhood Absence Epilepsy.

PubMed

Caplan, Rochelle; Levitt, Jennifer; Siddarth, Prabha; Wu, Keng Nei; Gurbani, Suresh; Sankar, Raman; Shields, W Donald

2009-11-01

This study compared frontotemporal brain volumes in children with childhood absence epilepsy (CAE) to age- and gender-matched children without epilepsy. It also examined the association of these volumes with seizure, demographic, perinatal, intelligence quotient (IQ), and psychopathology variables. Twenty-six children with CAE, aged 7.5-11.8 years, and 37 children without epilepsy underwent brain magnetic resonance imaging (MRI) scans at 1.5 Tesla. Tissue was segmented, and total brain, frontal lobe, frontal parcellations, and temporal lobe volumes were computed. All children had IQ testing and structured psychiatric interviews. Parents provided seizure, perinatal, and behavioral information on each child. The CAE group had significantly smaller gray matter volumes of the left orbital frontal gyrus as well as both left and right temporal lobes compared to the age- and gender-matched children without epilepsy. In the CAE group these volumes were related to age, gender, ethnicity, and pregnancy complications but not to seizure, IQ, and psychopathology variables. In the group of children without epilepsy, however, the volumes were related to IQ. These findings suggest that CAE impacts brain development in regions implicated in behavior, cognition, and language. In addition to supporting the cortical focus theory of CAE, these findings also imply that CAE is not a benign disorder.

Using EPIC to Find Conflicts, Inconsistencies, and Gaps in Department of Defense Policies

DTIC Science & Technology

2013-01-01

documentation; or deliver preliminary findings. All RAND reports un- dergo rigorous peer review to ensure that they meet high standards for research quality...responsibilities and the products that result from their execution. Once the high -level frame- work was defined, successive lower layers were developed to further...Lead or Chief Engineer Component Acquisition Executive ( CAE ) Managers Configuration Steering Board Materiel developer Contractor Milestone Decision

[An efficient strategy to decrease the central venous catheter-related adverse events rate in haemodialysis patients].

PubMed

Jean, Guillaume; Vanel, Thierry; Bresson, Eric; Terrat, Jean-Claude; Hurot, Jean-Marc; Lorriaux, Christie; Mayor, Brice; Chazot, Charles

2009-07-01

Catheter-related adverse events (CAE) remain a major cause of mortality and morbidity. We aimed to compare the CAE prevalence and adverse events rate at 10 years interval in one centre using different devices, dressing procedures. We compared two periods, from 1994 to 1997 (period 1) and from 2004 to 2007 (period 2). We recorded all prevalent tunnelled CAE and their related adverse event rate: catheter-related bacteraemia (CRB), catheter local infection (CLI), catheter dysfunction leading to CAE exchange, thrombolytic use and spontaneous pulling up. In period 1, PermCath catheter (Quinton, N=63) and TwinCath catheter (MedComp, N=76) were used in 95 HD. BioFlex catheter (N=52) and ASPC split catheter (MedComp, N=52) were used in 72 HD in period 2. In period 1, we performed catheter dressing using povidone iodine versus alcoholic chlorexidine in period 2. Between period 1 and period 2, the CAE prevalence decreased from 15-18% to 9-6%, CRB from 1.1 to 0.23/1000 day-catheter (p<0.001), CLI from 1.1 to 0.28/1000 day-catheter (p<0.001), definitive dysfunction from 12 to 1.2% (p<0.001) and CAE pulling up from 4 to 0%. The annual urokinase consumption decreased from three to one unit per CAE. This study shows the dramatic decrease in CAE prevalence (-50%) and related-adverse events (approximately -200%) since 10 years. Switching povidone iodine to chlorexidine and using more recent catheter devices appear very efficient in decreasing catheter-related adverse events.

A Comparison of the Single-sided (Gen II) and Double-sided (Gen I) Combat Arms Earplugs (CAE): Acoustic Properties, Human Performance, and User Acceptance

DTIC Science & Technology

2012-12-01

results of steady-state and impulse noise attenuation objective and real-ear measurements; localization and speech intelligibility human performance... Intelligibility 12 6.1 Method...12 Figure 8. Speech intelligibility testing of Gen I CAE and Gen II CAE

Childhood Adverse Events and Health Outcomes among Methamphetamine-Dependent Men and Women

ERIC Educational Resources Information Center

Messina, Nena P.; Marinelli-Casey, Patricia; Hillhouse, Maureen; Ang, Alfonso; Hunter, Jeremy; Rawson, Richard

2008-01-01

To describe the prevalence of childhood adverse events (CAEs) among methamphetamine-dependent men and women, and assess the relationship of cumulative CAEs to health problems. Data for 236 men and 351 women were analyzed assessing CAEs. Dependent variables included 14 self-reported health problems or psychiatric symptom domains. Mental health was…

Centella asiatica Leaf Extract Protects Against Indomethacin-Induced Gastric Mucosal Injury in Rats.

PubMed

Zheng, Hong-Mei; Choi, Myung-Joo; Kim, Jae Min; Cha, Kyung Hoi; Lee, Kye Wan; Park, Yu Hwa; Hong, Soon-Sun; Lee, Don Haeng

2016-01-01

The present study evaluated the protective effect of Centella asiatica (gotu kola) leaf extract (CAE) against indomethacin (IND)-induced gastric mucosal injury in rats. Gastric mucosal injury was induced by the oral administration of IND to the rats after a 24 h fast. CAE (50 or 250 mg/kg) or lansoprazole (a reference drug) was orally administrated 30 min before the IND administration, and 5 h later, the stomachs were removed to quantify the lesions. Orally administered CAE significantly reduced IND-induced gastric injury. The histopathological observations (hematoxylin-eosin and Periodic acid-Schiff staining) confirmed the protection against gastric mucosal injury. Also, CAE decreased the malondialdehyde content compared to the control group. Moreover, pretreatment with CAE resulted in a significant reduction in the elevated expression of tumor necrosis factor, Cyclooxygenase (COX)-2, and inducible nitric oxide synthase. These results suggested that CAE possesses gastroprotective effects against IND-induced gastric mucosal injury, which could be attributed to its ability to inhibit lipid peroxidation and stimulate gastric mucus secretion in the rat gastric mucosa.

Comparison of cefuroxime axetil and amoxicillin-clavulanate suspensions in treatment of acute otitis media with effusion in children.

PubMed Central

McLinn, S E; Moskal, M; Goldfarb, J; Bodor, F; Aronovitz, G; Schwartz, R; Self, P; Ossi, M J

1994-01-01

Two hundred sixty-three pediatric patients from the ages of 3 months to 11 years were enrolled in a randomized, investigator-blinded, multicenter study comparing the clinical and bacteriological efficacies and safety of cefuroxime axetil suspension (CAE) with those of amoxicillin-clavulanate suspension (AMX-CL) in the treatment of acute otitis media with effusion. Patients received CAE at 30 mg/kg of body weight per day (n = 165) in two divided doses or AMX-CL at 40 mg/kg/day (n = 98) in three divided doses for 10 days. The primary pathogens among 200 isolates from pretreatment cultures of middle ear fluid were identified as follows: Haemophilus influenzae (39%), over a third of which were beta-lactamase positive; Streptococcus pneumoniae (34%); and Moraxella catarrhalis (16%). Pathogens were eradicated or presumed to be eradicated from 81% (95 of 118) and 76% (50 of 66) of bacteriologically evaluable patients in the CAE and AMX-CL groups, respectively. A satisfactory clinical response (cure or improvement with or without resolution of effusion) occurred in 113 (77%) of 146 clinically evaluable patients in the CAE group and in 66 (74%) of 89 evaluable patients in the AMX-CL group. Clinical failure or recurrence (within 2 weeks following the completion of treatment) occurred in 22 and 26% of CAE- and AMX-CL-treated patients, respectively. Drug-related adverse events occurred in 18% of CAE-treated patients, whereas they occurred in 39% of AMX-CL-treated patients (P < 0.001); diarrhea or loose stools was the most commonly reported adverse event (CAE, 12%; AMX-CL, 31%; P < 0.001). These results indicate that CAE given twice daily is as effective as AMX-CL given three times daily in the treatment of acute otitis media with effusion in pediatric patients, but CAE was associated with significantly fewer drug-related adverse events. PMID:8192458

Anti-inflammatory and antioxidant activities of aqueous extract of Cecropia glaziovii leaves.

PubMed

Müller, Simony Davet; Florentino, Drielly; Ortmann, Caroline Flach; Martins, Fernanda Amélia; Danielski, Lucineia Gainski; Michels, Monique; de Souza Constantino, Larissa; Petronilho, Fabricia; Reginatto, Flavio Henrique

2016-06-05

Cecropia glaziovii Sneth leaves extract is widely used as a traditional folk medicine in Brazil, especially for the treatment of diabetes, and as an antihypertensive and antiinflammatory agent. To investigate the anti-inflammatory and antioxidant properties of crude aqueous extract (CAE) of C. glaziovii leaves. The in vivo anti-inflammatory and antioxidant effect of the CAE (10-300mg/kg, intragastrically) was investigated in the animal model of pleurisy. The cell migration, proinflammatory cytokines (TNF-α, IL-1β and IL-6), nitrite/nitrate concentration, myeloperoxidase (MPO) activity, oxidative damage in lipids and proteins, lactate dehydrogenase (LDH) activity and total protein content were also analyzed. Furthermore, the in vitro antioxidant activity of CAE was evaluated by the inhibition of formation of thiobarbituric acid reactive substances (TBARS), induced by free radical generators (H2O2, FeSO4 and AAPH) on a lipid-rich substrate. Hence, the chemical characterizarion of CAE by HPLC was therefore performed. The results showed that the inflammatory process caused by the administration of carragenin (Cg) into the pleural cavity resulted in a substantial increase in inflammatory parameters and oxidative damage. These levels seems to be reversed after CAE treatment in animals with similar results to Dexamethasone (Dex) treatment. Further, the CAE was effective in reducing proinflammatory cytokines, cell infiltrate, MPO activity, nitrite/nitrate concentration, LDH activity, and total protein levels with concomitant attenuation of all parameters associated with oxidative damage induced by Cg. Finally, the CAE presented in vitro antioxidant activity induced by free radical generators at all the concentrations investigated. HPLC analysis confirmed the presence of chlorogenic acid and C-glycosylflavonoids (isoorientin and isovitexin) as the major compounds of the CAE. CAE of C. glaziovii exerts significant antiinflammatory and antioxidant activities and this effect can be attributed, at least in part, to the presence of chlorogenic acid and the C-glycosylflavonoids. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Development of biomarkers of exposure to xenobiotics in the honey bee Apis mellifera: application to the systemic insecticide thiamethoxam.

PubMed

Badiou-Bénéteau, Alexandra; Carvalho, Stephan M; Brunet, Jean-Luc; Carvalho, Geraldo A; Buleté, Audrey; Giroud, Barbara; Belzunces, Luc P

2012-08-01

This study describes the development of acetylcholinesterase (AChE), carboxylesterases (CaE1, CaE2, CaE3), glutathion-S-transferase (GST), alkaline phosphatase (ALP) and catalase (CAT) as enzyme biomarkers of exposure to xenobiotics such as thiamethoxam in the honey bee Apis mellifera. Extraction efficiency, stability under freezing and biological variability were studied. The extraction procedure achieved good recovery rates in one extraction step and ranged from 65 percent (AChE) to 97.3 percent (GST). Most of the enzymes were stable at -20°C, except ALP that displayed a slight but progressive decrease in its activity. Modifications of enzyme activities were considered after exposure to thiamethoxam at the lethal dose 50 percent (LD(50), 51.16 ng bee(-1)) and two sublethal doses, LD(50)/10 (5.12 ng bee(-1)) and LD(50)/20 (2.56 ng bee(-1)). The biomarker responses revealed that, even at the lowest dose used, exposure to thiamethoxam elicited sublethal effects and modified the activity of CaEs, GST, CAT and ALP. Different patterns of biomarker responses were observed: no response for AChE, an increase for GST and CAT, and differential effects for CaEs isoforms with a decrease in CaE1 and CaE3 and an increase in CaE2. ALP and CaE3 displayed contrasting variations but only at 2.56 ng bee(-1). We consider that this profile of biomarker variation could represent a useful fingerprint to characterise exposure to thiamethoxam in the honey bee A. mellifera. This battery of honey bee biomarkers might be a promising option to biomonitor the health of aerial and terrestrial ecosystems and to generate valuable information on the modes of action of pesticides. Copyright © 2012 Elsevier Inc. All rights reserved.

Comparison of the acute effects of high-intensity interval training and continuous aerobic walking on inhibitory control.

PubMed

Kao, Shih-Chun; Westfall, Daniel R; Soneson, Jack; Gurd, Brendon; Hillman, Charles H

2017-09-01

The purpose of this study was to investigate the effects of a single bout of high-intensity interval training (HIIT) and continuous aerobic exercise (CAE) on inhibitory control. The P3 component of the stimulus-locked ERP was collected in 64 young adults during a modified flanker task following 20 min of seated rest, 20 min of CAE, and 9 min of HIIT on separate days in counterbalanced order. Participants exhibited shorter overall reaction time following CAE and HIIT compared to seated rest. Response accuracy improved following HIIT in the task condition requiring greater inhibitory control compared to seated rest and CAE. P3 amplitude was larger following CAE compared to seated rest and HIIT. Decreased P3 amplitude and latency were observed following HIIT compared to seated rest. The current results replicated previous findings indicating the beneficial effect of acute CAE on behavioral and neuroelectric indices of inhibitory control. With a smaller duration and volume of exercise, a single bout of HIIT resulted in additional improvements in inhibitory control, paralleled by a smaller and more efficient P3 component. In sum, the current study demonstrated that CAE and HIIT differentially facilitate inhibitory control and its underlying neuroelectric activation, and that HIIT may be a time-efficient approach for enhancing cognitive health. © 2017 Society for Psychophysiological Research.

Cultured autologous keratinocytes in the treatment of large and deep burns: a retrospective study over 15 years.

PubMed

Auxenfans, Celine; Menet, Veronique; Catherine, Zulma; Shipkov, Hristo; Lacroix, Pierre; Bertin-Maghit, Marc; Damour, Odile; Braye, Fabienne

2015-02-01

The aim was to review the use and indications of cultured autologous epidermis (CAE) in extensive burns and to evaluate the efficiency of our strategy of burn treatment. This retrospective study comprised 15 years (1997-2012). all patients who received CAE. patients who died before complete healing and patients who received exclusively cultured allogeneic keratinocytes. Evaluation criteria were clinical. Time and success of wound healing after CAE graft were evaluated. A total of 63 patients were included with severity Baux score of 107 (from 70 to 140) and mean percentage of TBSA of 71% (from 40% to 97%). The CAE were used as Cuono method, in STSG donor sites and deep 2nd degree burns and in combination with large-meshed STSG (1:6-1:12) in extensively burned patients. Cuono method was used in 6 patients. The final take was 16% (0-30) because of the great fragility of the obtained epidermis. Nine patients with deep 2nd degree burns (mean TBSA 81%, from 60 to 97%) were successfully treated with only CAE without skin grafting. Combined technique (STSG meshed at 1:6-1:12 covered with CAE) was used in 27 patients (mean TBSA 69%, from 49% to 96%) with 85% success rate. Finally, donor sites treated with CAE in 49 patients could be harvested several times thanks to rapid epithelialization (time of wound healing was 7 days (from 5 to 10 days)). The CAE allow rapid healing of STSG donor sites and deep 2nd second degree burns in extensively burned patients. Copyright © 2014 Elsevier Ltd and ISBI. All rights reserved.

Numerical methods for engine-airframe integration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Murthy, S.N.B.; Paynter, G.C.

1986-01-01

Various papers on numerical methods for engine-airframe integration are presented. The individual topics considered include: scientific computing environment for the 1980s, overview of prediction of complex turbulent flows, numerical solutions of the compressible Navier-Stokes equations, elements of computational engine/airframe integrations, computational requirements for efficient engine installation, application of CAE and CFD techniques to complete tactical missile design, CFD applications to engine/airframe integration, and application of a second-generation low-order panel methods to powerplant installation studies. Also addressed are: three-dimensional flow analysis of turboprop inlet and nacelle configurations, application of computational methods to the design of large turbofan engine nacelles, comparison ofmore » full potential and Euler solution algorithms for aeropropulsive flow field computations, subsonic/transonic, supersonic nozzle flows and nozzle integration, subsonic/transonic prediction capabilities for nozzle/afterbody configurations, three-dimensional viscous design methodology of supersonic inlet systems for advanced technology aircraft, and a user's technology assessment.« less

Experimental investigation of stability, frequency and toroidal mode number of compressional Alfvén eigenmodes in DIII-D

NASA Astrophysics Data System (ADS)

Tang, S.; Thome, K.; Pace, D.; Heidbrink, W. W.; Carter, T. A.; Crocker, N. A.; NSTX-U Collaboration; DIII-D Collaboration

2017-10-01

An experimental investigation of the stability of Doppler-shifted cyclotron resonant compressional Alfvén eigenmodes (CAE) using the flexible DIII-D neutral beams has begun to validate a theoretical understanding and realize the CAE's diagnostic potential. CAEs are excited by energetic ions from neutral beams [Heidbrink, NF 2006], with frequencies and toroidal mode numbers sensitive to the fast-ion phase space distribution, making them a potentially powerful passive diagnostic. The experiment also contributes to a predictive capability for spherical tokamak temperature profiles, where CAEs may play a role in energy transport [Crocker, NF 2013]. CAE activity was observed using the recently developed Ion Cyclotron Emission diagnostic-high bandwidth edge magnetic sensors sampled at 200 MS/s. Preliminary results show CAEs become unstable in BT ramp discharges below a critical threshold in the range 1.7 - 1.9 T, with the exact value increasing as density increases. The experiment will be used to validate simulations from relevant codes such as the Hybrid MHD code [Belova, PRL 2015]. This work was supported by US DOE Grants DE-SC0011810 and DE-FC02-04ER54698.

Integrated design and manufacturing for the high speed civil transport

NASA Technical Reports Server (NTRS)

1993-01-01

In June 1992, Georgia Tech's School of Aerospace Engineering was awarded a NASA University Space Research Association (USRA) Advanced Design Program (ADP) to address 'Integrated Design and Manufacturing for the High Speed Civil Transport (HSCT)' in its graduate aerospace systems design courses. This report summarizes the results of the five courses incorporated into the Georgia Tech's USRA ADP program. It covers AE8113: Introduction to Concurrent Engineering, AE4360: Introduction to CAE/CAD, AE4353: Design for Life Cycle Cost, AE6351: Aerospace Systems Design One, and AE6352: Aerospace Systems Design Two. AE8113: Introduction to Concurrent Engineering was an introductory course addressing the basic principles of concurrent engineering (CE) or integrated product development (IPD). The design of a total system was not the objective of this course. The goal was to understand and define the 'up-front' customer requirements, their decomposition, and determine the value objectives for a complex product, such as the high speed civil transport (HSCT). A generic CE methodology developed at Georgia Tech was used for this purpose. AE4353: Design for Life Cycle Cost addressed the basic economic issues for an HSCT using a robust design technique, Taguchi's parameter design optimization method (PDOM). An HSCT economic sensitivity assessment was conducted using a Taguchi PDOM approach to address the robustness of the basic HSCT design. AE4360: Introduction to CAE/CAD permitted students to develop and utilize CAE/CAD/CAM knowledge and skills using CATIA and CADAM as the basic geometric tools. AE6351: Aerospace Systems Design One focused on the conceptual design refinement of a baseline HSCT configuration as defined by Boeing, Douglas, and NASA in their system studies. It required the use of NASA's synthesis codes FLOPS and ACSYNT. A criterion called the productivity index (P.I.) was used to evaluate disciplinary sensitivities and provide refinements of the baseline HSCT configuration. AE6352: Aerospace Systems Design Two was a continuation of Aerospace Systems Design One in which wing concepts were researched and analyzed in more detail. FLOPS and ACSYNT were again used at the system level while other off-the-shelf computer codes were used for more detailed wing disciplinary analysis and optimization. The culmination of all efforts and submission of this report conclude the first year's efforts of Georgia Tech's NASA USRA ADP. It will hopefully provide the foundation for next year's efforts concerning continuous improvement of integrated design and manufacturing for the HSCT.

Design of a miniature hydrogen fueled gas turbine engine

NASA Technical Reports Server (NTRS)

Burnett, M.; Lopiccolo, R. C.; Simonson, M. R.; Serovy, G. K.; Okiishi, T. H.; Miller, M. J.; Sisto, F.

1973-01-01

The design, development, and delivery of a miniature hydrogen-fueled gas turbine engine are discussed. The engine was to be sized to approximate a scaled-down lift engine such as the teledyne CAE model 376. As a result, the engine design emerged as a 445N(100 lb.)-thrust engine flowing 0.86 kg (1.9 lbs.) air/sec. A 4-stage compressor was designed at a 4.0 to 1 pressure ratio for the above conditions. The compressor tip diameter was 9.14 cm (3.60 in.). To improve overall engine performance, another compressor with a 4.75 to 1 pressure ratio at the same tip diameter was designed. A matching turbine for each compressor was also designed. The turbine tip diameter was 10.16 cm (4.0 in.). A combustion chamber was designed, built, and tested for this engine. A preliminary design of the mechanical rotating parts also was completed and is discussed. Three exhaust nozzle designs are presented.

Molecular-Level Study of the Effect of Prior Axial Compression/Torsion on the Axial-Tensile Strength of PPTA Fibers

DTIC Science & Technology

2013-07-16

Twaron, etc., which are characterized by high specific strength and high specific stiffness. Fibers of this type are often referred to as ‘‘ballistic... high level of penetration resistance against large kinetic energy projectiles, such as bullets, detonated-mine-induced soil ejecta, improvised...increasingly being designed and developed through an extensive use of computer-aided engineering ( CAE ) methods and tools. The utility of these

Technical Feasibility of Compressed Air Energy Storage (CAES) Utilizing a Porous Rock Reservoir (Appendix)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Medeiros, Michael

Pacific Gas & Electric Company (PG&E) conducted a project to explore the viability of underground compressed air energy storage (CAES) technology. CAES uses low-cost, off-peak electricity to compress air into a storage system in an underground space such as a rock formation or salt cavern. When electricity is needed, the air is withdrawn and used to drive a generator for electricity production.

Technical Feasibility of Compressed Air Energy Storage (CAES) Utilizing a Porous Rock Reservoir

DOE Office of Scientific and Technical Information (OSTI.GOV)

Medeiros, Michael; Booth, Robert; Fairchild, James

Pacific Gas & Electric Company (PG&E) conducted a project to explore the viability of underground compressed air energy storage (CAES) technology. CAES uses low-cost, off-peak electricity to compress air into a storage system in an underground space such as a rock formation or salt cavern. When electricity is needed, the air is withdrawn and used to drive a generator for electricity production.

High-performance genetic analysis on microfabricated capillary array electrophoresis plastic chips fabricated by injection molding.

PubMed

Dang, Fuquan; Tabata, Osamu; Kurokawa, Masaya; Ewis, Ashraf A; Zhang, Lihua; Yamaoka, Yoshihisa; Shinohara, Shouji; Shinohara, Yasuo; Ishikawa, Mitsuru; Baba, Yoshinobu

2005-04-01

We have developed a novel technique for mass production of microfabricated capillary array electrophoresis (mu-CAE) plastic chips for high-speed, high-throughput genetic analysis. The mu-CAE chips, containing 10 individual separation channels of 50-microm width, 50-microm depth, and a 100-microm lane-to-lane spacing at the detection region and a sacrificial channel network, were fabricated on a poly(methyl methacrylate) substrate by injection molding and then bonded manually using a pressure-sensitive sealing tape within several seconds at room temperature. The conditions for injection molding and bonding were carefully characterized to yield mu-CAE chips with well-defined channel and injection structures. A CCD camera equipped with an image intensifier was used to monitor simultaneously the separation in a 10-channel array with laser-induced fluorescence detection. High-performance electrophoretic separations of phiX174 HaeIII DNA restriction fragments and PCR products related to the human beta-globin gene and SP-B gene (the surfactant protein B) have been demonstrated on mu-CAE plastic chips using a methylcellulose sieving matrix in individual channels. The current work demonstrated greatly simplified the fabrication process as well as a detection scheme for mu-CAE chips and will bring the low-cost mass production and application of mu-CAE plastic chips for genetic analysis.

Serum proteins by capillary zone electrophoresis: approaches to the definition of reference values.

PubMed

Petrini, C; Alessio, M G; Scapellato, L; Brambilla, S; Franzini, C

1999-10-01

The Paragon CZE 2000 (Beckman Analytical, Milan, Italy) is an automatic dedicated capillary zone electrophoresis (CZE) system, producing a five-zone serum protein pattern with quantitative estimation of the zones. With the view of substituting this instrument for two previously used serum protein electrophoresis techniques, we planned to produce reference values for the "new" systems leading to compatible interpretation of the results. High resolution cellulose acetate electrophoresis with visual inspection and descriptive reporting (HR-CAE) and five-zone cellulose acetate electrophoresis with densitometry (CAE-D) were the previously used techniques. Serum samples (n = 167) giving "normal pattern" with HR-CAE were assayed with the CZE system, and the results were statistically assessed to yield 0.95 reference intervals. One thousand normal and pathological serum samples were then assayed with the CAE-D and the CZE techniques, and the regression equations of the CAE-D values over the CZE values for the five zones were used to transform the CAE-D reference limits into the CZE reference limits. The two sets of reference values thereby produced were in good agreement with each other and also with reference values previously reported for the CZE system. Thus, reference values for the CZE techniques permit interpretation of results coherent with the previously used techniques and reporting modes.

Comparison of cefuroxime axetil, cefaclor, and amoxicillin-clavulanate potassium suspensions in acute otitis media in infants and children.

PubMed

Pichichero, M; Aronovitz, G H; Gooch, W M; McLinn, S E; Maddern, B; Johnson, C; Darden, P M

1990-10-01

In this randomized, blinded, multicenter comparison study, 377 infants and children with acute otitis media (AOM) received a 10-day course of an oral suspension of one of the following: cefuroxime axetil (CAE), 30 mg/kg/day; cefaclor (CEC), 40 mg/kg/day; or amoxicillin-clavulanate potassium (AMX-CL), 40 mg/kg/day. Clinical efficacy was determined by pneumatic otoscopy and tympanometric testing 3 to 5, 11 to 14, and 22 to 26 days after the initiation of therapy. There was a statistically significant difference among the three treatment groups with respect to clinical outcome; more patients in the CAE group (62%) than in the CEC group (46%) or the AMX-CL group (52%) had complete resolution of signs and symptoms of AOM (including effusion). Paired comparisons revealed a significant difference in efficacy between CAE and CEC and a nearly significant difference between AMX-CL and CEC. Taste acceptability was highest for CEC and lowest for this formulation of CAE. Significantly more patients in the AMX-CL group than in the CAE or CEC group had a side effect, primarily diarrhea, vomiting, or diaper rash. We conclude that CAE suspension has greater clinical efficacy than CEC and fewer side effects than AMX-CL.

NASA Center for Astronomy Education: Building a Community of Practice

NASA Astrophysics Data System (ADS)

Brissenden, Gina; Prather, E.; Slater, T. F.; Greene, W. M.; Thaller, M.

2006-12-01

The NASA Center for Astronomy Education (CAE) is devoted to the professional development of introductory college astronomy instructors teaching at community colleges. The primary goal is building a "community of practice." Evaluation results suggest this community of practice model is effective at improving instructional practices, particularly in settings where instructors feel isolated from their peers. For community college faculty this isolation can be quite real. Many are the only astronomer, if not the only scientist, at their institution. In addition, they may be adjunct instructors who have no office, no institutional email address, nor appear in the campus directory. CAE works to prevent this sense of isolation by building both actual and virtual communities for these instructors, as well as provide actual and virtual professional development opportunities. CAE’s major effort is providing multi-tiered "Teaching Excellence Workshops" offered at national and regional venues. Ongoing support is offered through the CAE website. Instructors can learn about, and register for, upcoming workshops. They can engage in discussions about educational issues and share best practices with peers using the moderated discussion group AstroLrner@CAE. CAE also provides an updated article "This Month’s Teaching Strategy” which is a reflection on teaching strategies discussed in the workshops. Instructors can also find their peers through the online map of US community colleges offering introductory astronomy courses. Lastly, CAE Regional Teaching Exchanges facilitate local, and sustained, community building. CAE is supported by the NASA/JPL Navigator Public Engagement Program and the Spitzer Space Telescope Education and Public Outreach Program.

Alertness Modulates Conflict Adaptation and Feature Integration in an Opposite Way

PubMed Central

Chen, Jia; Huang, Xiting; Chen, Antao

2013-01-01

Previous studies show that the congruency sequence effect can result from both the conflict adaptation effect (CAE) and feature integration effect which can be observed as the repetition priming effect (RPE) and feature overlap effect (FOE) depending on different experimental conditions. Evidence from neuroimaging studies suggests that a close correlation exists between the neural mechanisms of alertness-related modulations and the congruency sequence effect. However, little is known about whether and how alertness mediates the congruency sequence effect. In Experiment 1, the Attentional Networks Test (ANT) and a modified flanker task were used to evaluate whether the alertness of the attentional functions had a correlation with the CAE and RPE. In Experimental 2, the ANT and another modified flanker task were used to investigate whether alertness of the attentional functions correlate with the CAE and FOE. In Experiment 1, through the correlative analysis, we found a significant positive correlation between alertness and the CAE, and a negative correlation between the alertness and the RPE. Moreover, a significant negative correlation existed between CAE and RPE. In Experiment 2, we found a marginally significant negative correlation between the CAE and the RPE, but the correlation between alertness and FOE, CAE and FOE was not significant. These results suggest that alertness can modulate conflict adaptation and feature integration in an opposite way. Participants at the high alerting level group may tend to use the top-down cognitive processing strategy, whereas participants at the low alerting level group tend to use the bottom-up processing strategy. PMID:24250824

Use of circulating-fluidized-bed combustors in compressed-air energy storage systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nakhamkin, M.; Patel, M.

1990-07-01

This report presents the result of a study conducted by Energy Storage and Power Consultants (ESPC), with the objective to develop and analyze compressed air energy storage (CAES) power plant concepts which utilize coal-fired circulating fluidized bed combustors (CFBC) for heating air during generating periods. The use of a coal-fired CFBC unit for indirect heating of the compressed air, in lieu of the current turbomachinery combustors, would eliminate the need for expensive premium fuels by a CAES facility. The CAES plant generation heat rate is approximately one-half of that for a conventional steam condensing power plant. Therefore, the required CFBCmore » heat generation capacity and capital costs would be lower per kW of power generation capacity. Three CAES/CFBC concepts were identified as the most promising, and were optimized using specifically developed computerized procedures. These concepts utilize various configurations of reheat turbomachinery trains specifically developed for CAES application as parts of the integrated CAES/CFBC plant concepts. The project team concluded that the optimized CAES/CFBC integrated plant concepts present a potentially attractive alternative to conventional steam generation power plants using CFBC or pulverized coal-fired boilers. A comparison of the results from the economic analysis performed on three concepts suggests that one of them (Concept 3) is the preferred concept. This concept has a two shaft turbomachinery train arrangement, and provides for load management functions by the compressor-electric motor train, and continuous base load operation of the turboexpander-electric generator train and the CFBC unit. 6 refs., 30 figs., 14 tabs.« less

Evaluation of longitudinal left ventricular function in patients with coronary artery ectasia and vitamin D deficiency by 2D speckle tracking echocardiography.

PubMed

Aghajani, Hasan; Faal, Mohsen; Hosseinsabet, Ali

2017-03-01

Coronary artery ectasia (CAE) is defined as the dilation of at least one segment of the coronary arteries that reaches at least 1.5 times the size of a normal neighboring segment. It has been shown that left ventricular (LV) diastolic function is impaired in patients with CAE. Also, it has been shown that LV function is impaired in vitamin D-deficient subjects compared with vitamin D-sufficient subjects and vitamin D deficiency is prevalent in CAE patients. We hypothesized that LV function is impaired in patients with CAE so we evaluated longitudinal LV myocardial function by 2D speckle tracking echocardiography (2DSTE) in patients with CAE and vitamin D deficiency without significant coronary artery stenosis and compared the results with those of subjects with vitamin D deficiency and near-normal coronary arteries. Our study population comprised 21 consecutive patients with CAE and without significant coronary artery stenosis (<50%) and 31 control subjects with near-normal coronary arteries. All subjects had vitamin D deficiency. All 2DSTE-derived indices of longitudinal LV function, comprised of the absolute values of systolic strain (14.0±2.7% vs 15.4±2.3%, P=.039), systolic strain rate (1.2±0.2/s vs 1.3±0.2/s, P=.015), early diastolic strain rate (1.1±0.3/s vs 1.3±0.3 s -1 , P=.030), and late diastolic strain rate (0.8±0.2/s vs 1±0.2/s , P=.005), were reduced in the patients with CAE and vitamin D deficiency. The systolic and diastolic functions of the LV in the patients with CAE and vitamin D deficiency were impaired as evaluated by 2DSTE. © 2017, Wiley Periodicals, Inc.

NASA Center for Astronomy Education: Building a Community of Practice

NASA Astrophysics Data System (ADS)

Brissenden, Gina; Prather, E. E.; Slater, T. F.; Greene, W. M.; Thaller, M.; Alvidrez, R.

2007-12-01

The NASA Center for Astronomy Education (CAE) is devoted to the professional development of introductory college astronomy instructors teaching at community colleges. The primary goal is building a "community of practice." Evaluation results suggest this community of practice model is effective at improving instructional practices, particularly in settings where instructors feel isolated from their peers. For community college faculty this isolation can be quite real. Many are the only astronomer, if not the only scientist, at their institution. In addition, they may be adjunct instructors who have no office, no institutional email address, nor appear in the campus directory. CAE works to prevent this sense of isolation by building both actual and virtual communities for these instructors, as well as provide actual and virtual professional development opportunities. CAE's major effort is providing multi-tiered "Teaching Excellence Workshops" offered at national and regional venues. Recently added to our workshop offerings is a Tier II, or advanced, workshop for instructors who have attended a previous Teaching Excellence Workshop. The focus of the Tier II workshops is on implementation issues. In addition, we are now also offering a workshop exclusively for post-docs, graduates, and undergraduate students. Ongoing support is offered through the CAE website. Instructors can learn about, and register for, upcoming workshops. They can engage in discussions about educational issues and share best practices with peers using the moderated discussion group Astrolrner@CAE. CAE also provides an updated article "This Month's Teaching Strategy” which is a reflection on teaching strategies discussed in the workshops. Instructors can also find their peers through the online map of US community colleges offering introductory astronomy courses. Lastly, CAE Regional Teaching Exchanges facilitate local, and sustained, community building. CAE is supported by the NASA/JPL Navigator Public Engagement Program and the Spitzer Space Telescope Education and Public Outreach Program.

Modeling of Single and Dual Reservoir Porous Media Compressed Gas (Air and CO2) Storage Systems

NASA Astrophysics Data System (ADS)

Oldenburg, C. M.; Liu, H.; Borgia, A.; Pan, L.

2017-12-01

Intermittent renewable energy sources are causing increasing demand for energy storage. The deep subsurface offers promising opportunities for energy storage because it can safely contain high-pressure gases. Porous media compressed air energy storage (PM-CAES) is one approach, although the only facilities in operation are in caverns (C-CAES) rather than porous media. Just like in C-CAES, PM-CAES operates generally by injecting working gas (air) through well(s) into the reservoir compressing the cushion gas (existing air in the reservoir). During energy recovery, high-pressure air from the reservoir is mixed with fuel in a combustion turbine to produce electricity, thereby reducing compression costs. Unlike in C-CAES, the storage of energy in PM-CAES occurs variably across pressure gradients in the formation, while the solid grains of the matrix can release/store heat. Because air is the working gas, PM-CAES has fairly low thermal efficiency and low energy storage density. To improve the energy storage density, we have conceived and modeled a closed-loop two-reservoir compressed CO2 energy storage system. One reservoir is the low-pressure reservoir, and the other is the high-pressure reservoir. CO2 is cycled back and forth between reservoirs depending on whether energy needs to be stored or recovered. We have carried out thermodynamic and parametric analyses of the performance of an idealized two-reservoir CO2 energy storage system under supercritical and transcritical conditions for CO2 using a steady-state model. Results show that the transcritical compressed CO2 energy storage system has higher round-trip efficiency and exergy efficiency, and larger energy storage density than the supercritical compressed CO2 energy storage. However, the configuration of supercritical compressed CO2 energy storage is simpler, and the energy storage densities of the two systems are both higher than that of PM-CAES, which is advantageous in terms of storage volume for a given power rating.

Plitidepsin Has a Safe Cardiac Profile: A Comprehensive Analysis

PubMed Central

Soto-Matos, Arturo; Szyldergemajn, Sergio; Extremera, Sonia; Miguel-Lillo, Bernardo; Alfaro, Vicente; Coronado, Cinthya; Lardelli, Pilar; Roy, Elena; Corrado, Claudia Silvia; Kahatt, Carmen

2011-01-01

Plitidepsin is a cyclic depsipeptide of marine origin in clinical development in cancer patients. Previously, some depsipeptides have been linked to increased cardiac toxicity. Clinical databases were searched for cardiac adverse events (CAEs) that occurred in clinical trials with the single-agent plitidepsin. Demographic, clinical and pharmacological variables were explored by univariate and multivariate logistic regression analysis. Forty-six of 578 treated patients (8.0%) had at least one CAE (11 patients (1.9%) with plitidepsin-related CAEs), none with fatal outcome as a direct consequence. The more frequent CAEs were rhythm abnormalities (n = 31; 5.4%), mostly atrial fibrillation/flutter (n = 15; 2.6%). Of note, life-threatening ventricular arrhythmias did not occur. Myocardial injury events (n = 17; 3.0%) included possible ischemic-related and non-ischemic events. Other events (miscellaneous, n = 6; 1.0%) were not related to plitidepsin. Significant associations were found with prostate or pancreas cancer primary diagnosis (p = 0.0017), known baseline cardiac risk factors (p = 0.0072), myalgia present at baseline (p = 0.0140), hemoglobin levels lower than 10 g/dL (p = 0.0208) and grade ≥2 hypokalemia (p = 0.0095). Treatment-related variables (plitidepsin dose, number of cycles, schedule and/or total cumulative dose) were not associated. Electrocardiograms performed before and after plitidepsin administration (n = 136) detected no relevant effect on QTc interval. None of the pharmacokinetic parameters analyzed had a significant impact on the probability of developing a CAE. In conclusion, the most frequent CAE type was atrial fibrillation/atrial flutter, although its frequency was not different to that reported in the age-matched healthy population, while other CAEs types were rare. No dose-cumulative pattern was observed, and no treatment-related variables were associated with CAEs. Relevant risk factors identified were related to the patient’s condition and/or to disease-related characteristics rather than to drug exposure. Therefore, the current analysis supports a safe cardiac risk profile for single-agent plitidepsin in cancer patients. PMID:21747745

Technical Feasibility of Compressed Air Energy Storage (CAES) Utilizing a Porous Rock Reservoir, Appendix — Chapter 7

DOE Office of Scientific and Technical Information (OSTI.GOV)

Medeiros, Michael

Pacific Gas & Electric Company (PG&E) conducted a project to explore the viability of underground compressed air energy storage (CAES) technology. CAES uses low-cost, off-peak electricity to compress air into a storage system in an underground space such as a rock formation or salt cavern. When electricity is needed, the air is withdrawn and used to drive a generator for electricity production.

Technical Feasibility of Compressed Air Energy Storage (CAES) Utilizing a Porous Rock Reservoir, Appendix — Chapter 6

DOE Office of Scientific and Technical Information (OSTI.GOV)

Medeiros, Michael

Pacific Gas & Electric Company (PG&E) conducted a project to explore the viability of underground compressed air energy storage (CAES) technology. CAES uses low-cost, off-peak electricity to compress air into a storage system in an underground space such as a rock formation or salt cavern. When electricity is needed, the air is withdrawn and used to drive a generator for electricity production.

Technical Feasibility of Compressed Air Energy Storage (CAES) Utilizing a Porous Rock Reservoir, Appendix — Chapter 4

DOE Office of Scientific and Technical Information (OSTI.GOV)

Medeiros, Michael

Pacific Gas & Electric Company (PG&E) conducted a project to explore the viability of underground compressed air energy storage (CAES) technology. CAES uses low-cost, off-peak electricity to compress air into a storage system in an underground space such as a rock formation or salt cavern. When electricity is needed, the air is withdrawn and used to drive a generator for electricity production.

Technical Feasibility of Compressed Air Energy Storage (CAES) Utilizing a Porous Rock Reservoir, Appendix — Chapter 9

DOE Office of Scientific and Technical Information (OSTI.GOV)

Medeiros, Michael

Pacific Gas & Electric Company (PG&E) conducted a project to explore the viability of underground compressed air energy storage (CAES) technology. CAES uses low-cost, off-peak electricity to compress air into a storage system in an underground space such as a rock formation or salt cavern. When electricity is needed, the air is withdrawn and used to drive a generator for electricity production.

Technical Feasibility of Compressed Air Energy Storage (CAES) Utilizing a Porous Rock Reservoir, Appendix — Chapter 3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Medeiros, Michael

Pacific Gas & Electric Company (PG&E) conducted a project to explore the viability of underground compressed air energy storage (CAES) technology. CAES uses low-cost, off-peak electricity to compress air into a storage system in an underground space such as a rock formation or salt cavern. When electricity is needed, the air is withdrawn and used to drive a generator for electricity production.

Technical Feasibility of Compressed Air Energy Storage (CAES) Utilizing a Porous Rock Reservoir, Appendix — Chapter 5

DOE Office of Scientific and Technical Information (OSTI.GOV)

Medeiros, Michael

Pacific Gas & Electric Company (PG&E) conducted a project to explore the viability of underground compressed air energy storage (CAES) technology. CAES uses low-cost, off-peak electricity to compress air into a storage system in an underground space such as a rock formation or salt cavern. When electricity is needed, the air is withdrawn and used to drive a generator for electricity production.

Technical Feasibility of Compressed Air Energy Storage (CAES) Utilizing a Porous Rock Reservoir, Appendix — Chapter 8

DOE Office of Scientific and Technical Information (OSTI.GOV)

Medeiros, Michael

Pacific Gas & Electric Company (PG&E) conducted a project to explore the viability of underground compressed air energy storage (CAES) technology. CAES uses low-cost, off-peak electricity to compress air into a storage system in an underground space such as a rock formation or salt cavern. When electricity is needed, the air is withdrawn and used to drive a generator for electricity production.

Recuperators for compressed-air energy storage plants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nakhamkin, M.

1989-12-01

An R D study was conducted to provide an engineering solution to the potential problem of corrosion in the cold-end sections of recuperators operating in compressed-air energy storage (CAES) plants. Two options were developed: (1) a conventional, counterflow recuperator with an easily replaceable cold-end section and (2) a recuperator design which eliminates operation at tube temperatures below the exhaust-gas dew point (advanced design). The advanced design consists of an optimized combination of counterflow and parallel-flow sections. The following data resulting from these studies are included: a history of recuperator operating experience, a summary of lab-testing of various materials for corrosionmore » resistance, detailed design and descriptions of the recuperator designs, additional detail descriptions of alternative air-preheating and turboexpander-exhaust systems, and a comparative economic analysis of the various designs developed. The study concluded that for use with No. 2 fuel oil or lower-grade fuels, the advanced recuperator design with carbon-steel tubes and fins would be more cost-effective and trouble-free than one with an easily replaceable tube section. For CAES plants firing very low-sulfur fuel oil or natural gas, the lower capital-cost, counter-flow design can be considered. It was also concluded that a compressed-air bypass of the recuperator be included in the plant design in the event of recuperator outage, and that the recuperator be designed for operation without cavern air going through it. The advanced recuperator concept is currently being implemented at the 110-MW CAES plant for the Alabama Electric Cooperative, Inc. 6 refs., 24 figs., 20 tabs.« less

Numerical Simulation of Blast Action on Civil Structures in Urban Environment

NASA Astrophysics Data System (ADS)

Valger, Svetlana A.; Fedorova, Natalya N.; Fedorov, Alexander V.

2017-10-01

Nowadays, a lot of industrial accidents accompanied by explosions are happening throughout the world. Also, increase in the number of terrorist acts committed by means of explosions is observed. For improving safety of buildings and structures it is necessary to raise their resistance to explosive effects, as well as to be able to predict degree of potential damage upon explosive loads of various intensities. One of the principal goals in designing the structure resistant to explosive effects is to determine the dynamic response of structures to the impact of the blast wave. To this end, the transient pressure loads on the walls of the civil engineering structures are to be determined. The simulation of explosion is highly complicated, involving an explosion causing the shock wave propagation in air and then interaction with a structure. The engineering-level techniques permit one to estimate an explosive shock impact only for isolated buildings. The complexity of the building, the presence of nearby structures and the surrounding environment cannot be taken into account. Advanced computer aid engineering (CAE) software techniques combined with the latest methods of discrete three-dimensional city modelling permits one to simulate and analyse the effects of explosions in urban areas with a precision which previously was not possible. In the paper, the simulation results are presented of shock wave forming due to a spherical explosive charge and its propagation in the vicinity of geometrical configuration imitating an urban environment. The numerical simulation of a flow in the vicinity of prisms of different cross-sections and heights located on a flat plate was performed. The calculations are carried out in a three-dimensional non-viscous formulation using ANSYS software. On a basis of simulation results, a complex wave structures were analysed, and all the peculiarities of flows and pressure history records on building walls were described and explained. The possibility of a correct description of the non-stationary wave flow in the vicinity of the complex of obstacles is demonstrated. The results are compared with the experimental data on the pressure distribution in gauges located on the prism walls. The estimation of shock wave exposure intensity was performed to different objects.

Practice on Upbringing Young Engineers Collaborated with Local Enterprises

NASA Astrophysics Data System (ADS)

Hiraki, Yutaka; Uno, Naotsugu; Tanaka, Yuichi; Iyama, Hirofumi; Yamashita, Toru; Miyamoto, Noritaka

The ministry of Economics and Industry started the project collaborated with National Colleges of Technology titled “Upbringing Young Engineers in small and medium-sized enterprises” , in 2006. In our college, the authors planed the upbringing-program for the die-cast engineer in automobile industries collaborated with several enterprises in neighboring area and applied for the project. The program was adopted and worked out the concrete curriculum for the first year. The curriculum contains the training of the base of mechanical design with 3D-CAD/CAE/CAM systems and the practical training on manufacturing, by means of Problem Based Learning method. The program carried out in September and finished in December successfully. This paper reports the outline of the curriculum and the results in the program.

The application of virtual prototyping methods to determine the dynamic parameters of mobile robot

NASA Astrophysics Data System (ADS)

Kurc, Krzysztof; Szybicki, Dariusz; Burghardt, Andrzej; Muszyńska, Magdalena

2016-04-01

The paper presents methods used to determine the parameters necessary to build a mathematical model of an underwater robot with a crawler drive. The parameters present in the dynamics equation will be determined by means of advanced mechatronic design tools, including: CAD/CAE software andMES modules. The virtual prototyping process is described as well as the various possible uses (design adaptability) depending on the optional accessories added to the vehicle. A mathematical model is presented to show the kinematics and dynamics of the underwater crawler robot, essential for the design stage.

The optimal design of the bed structure of bedstand based on ABAQUS

NASA Astrophysics Data System (ADS)

Yang, Xudong; Dong, Yu; Ge, Qingkuan; Wang, Song

2017-12-01

Hydraulic transmission bedstand is one kind of the most commonly used in engineering machinery companies, and the bed structure is the most important part. Based on the original hydraulic transmission bedstand bed structure and the CAE technology, the original bed structure is improved. The optimized bed greatly saves the material of the production bed and improves the seismic performance of the bed. In the end, the performance of the optimized bed was compared with the original bed.

Multi-Plane High Speed Balancing Techniques and the Use of a High Specific Stiffness Ti-Borsic Material for Vibration Control.

DTIC Science & Technology

1980-02-01

maneuver conditions, and transmit the net axial thrust force between the turbine and fan sections due to pressure and aero dynamic gas loads . 49 Lm...stiffness composite material shaft. Both~~ balancing demonstration and the composite shaft design ad as their objective the management of small turbofan ...CONFIGURATIONS 99 LIST OF ILLUSTRATIONS Figure Title Page 1 High Speed Balancing Program Schedule 4 2 Teledyne CAE Model 471-11DX Turbofan Engine

Effect of Concentrated Apple Extract on Experimental Colitis Induced by Acetic Acid.

PubMed

Pastrelo, Maurício Mercaldi; Dias Ribeiro, Carla Caroline; Duarte, Joselmo Willamys; Bioago Gollücke, Andréa Pitelli; Artigiani-Neto, Ricardo; Ribeiro, Daniel Araki; Miszputen, Sender Jankiel; Fujiyama Oshima, Celina Tizuko; Ribeiro Paiotti, Ana Paula

2017-01-01

Reactive oxygen and nitrogen species (ROS/RNS) play a crucial role in inflammatory bowel disease (IBD) exacerbating the chronic inflammatory process. Endogenous and diet antioxidants can neutralize these compounds. The apple is widely consumed, with several antioxidant activity compounds. The present study evaluated the effects of concentrated apple extract (CAE) in acetic acid induced colitis. 29 Wistar male rats were randomized into 5 groups. G1-Sham/saline solution, G2-CAE/control, G3-acetic acid/control, G4-curative- CAE treatment and G5-preventive-CAE treatment. Eight days later, the animals were euthanized and the colonic segment resected for macroscopic and histological analysis. Gene expression was evaluated for inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), catalase and copper and zinc superoxide dismutase (CuZnSOD) by quantitative real time PCR, while protein expression was assessed for iNOS, COX-2 and 8-hydroxy-20-deoxyguanosine (8-OHdG) via immunohistochemistry. The groups G3, G4 and G5 had weight loss, while G5 had weight increase at the end of the experiment. The treatment with CAE reduced the macroscopic and microscopic injury, decreased iNOS mRNA expression and increased CuZnSOD mRNA expression in animals with induced acetic acid-colitis. The findings of the present study suggest that CAE treatment exerts an antioxidant role by downregulating iNOS and upregulating CuZnSOD.

Biological effects of aqueous extract from Turkey vulture Cathartes aura (Cathartidae) meat.

PubMed

Jacobo-Salcedo, Maria del Rosario; Juárez-Vázquez, Maria del Carmen; González-Espíndola, Luis Ángel; Maciel-Torres, Sandra Patricia; García-Carrancá, Alejandro; Alonso-Castro, Angel Josabad

2013-01-30

Cathartes aura is a bird used in the Mexican traditional medicine for the empirical treatment of cancer, injuries, infections and burns. The in vitro immunomodulatory effects of Cathartes aura extract (CAE) were evaluated estimating its effects on proliferation of human peripheral blood mononuclear cells and murine splenocytes. The effects of CAE (1-200 μg/ml) on NO production, pinocytosis and lysosomal enzyme activity were assayed in murine macrophages RAW 264.7. The cytotoxic effects of CAE (1-500 μg/ml) on tumorigenic and non tumorigenic cells were evaluated using the MTT assay. In the absence of LPS, CAE induced the proliferation of murine splenocytes (119%), enhanced the pinocytosis (113%) and lysosomal enzyme activity (141%) in murine macrophages with a similar potency than lypopolisaccharides 1 μg/ml. In addition, CAE exerted cytotoxic effects mainly on human cervical cancer cells (IC(50)=117 μg/ml) but lacked toxic effects on non tumorigenic cells (IC(50)>500 μg/ml). Cathartes aura exerts immunostimulatory and cytotoxic activities. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Isolation, characterisation and biological evaluation of a phenoxazine, a natural dyestuff isolated from leaves of Peristrophe bivalvis.

PubMed

Thuy, Trinh Thi; Huong, Nguyen Thi Thanh; Nhung, Le Thi Hong; Ninh, Pham Thi; Delfino, Domenico V; Van Sung, Tran

2013-04-01

Peristrophe bivalvis (L.) Merr. (Acanthaceae) is a wild growing and cultivated plant used for dyeing of foods by the ethnic minorities of Vietnam. The major component of the colour aqueous extract (CAE) of its leaves was identified as peristrophine by spectral analysis, especially the 2D NMR spectra (HSQC, HMBC and NOESY). Considering the widespread utilisation of the decoction of this plant for food dyeing, we evaluated the acute oral toxicity of the CAE. Based on the results in an acute toxicity study in mice, the LD50 value of the CAE was determined as 9100 ± 290 mg kg(-1) body weight. Additionally, in vitro cytotoxic assay showed an inhibition of peristrophine against Hepatocellular carcinoma (HepG2, IC503.90 µg mL(-1)). CAE and peristrophine (1) have also been tested for their ability to affect the cell number of the OCI acute myeloid leukaemia cell line. CAE and peristrophine significantly decreased the OCI cell number at different concentrations and times of treatment.

Attention impairment in childhood absence epilepsy: an impulsivity problem?

PubMed

Cerminara, Caterina; D'Agati, Elisa; Casarelli, Livia; Kaunzinger, Ivo; Lange, Klaus W; Pitzianti, Mariabernarda; Parisi, Pasquale; Tucha, Oliver; Curatolo, Paolo

2013-05-01

Although attention problems have often been described in children with childhood absence epilepsy (CAE), the use of different methodological approaches, neuropsychological tests, and heterogeneous experimental groups has prevented identification of the selective areas of attention deficit in this population. In this study, we investigated several components of attention in children with CAE using a unique computerized test battery for attention performance. Participants included 24 patients with CAE and 24 controls matched for age and sex. They were tested with a computerized test battery, which included the following tasks: selective attention, impulsivity, focused attention, divided attention, alertness, and vigilance. Compared with healthy controls, patients with CAE made more commission errors in the Go/No-Go task and more omission errors in the divided attention task. Childhood absence epilepsy patients also showed decreased reaction times in measures of selective attention and a great variability of reaction times in alertness and Go/No-Go tasks. Our findings suggest that patients with CAE were impaired in tonic and phasic alertness, divided attention, selective attention, and impulsivity. Copyright © 2013 Elsevier Inc. All rights reserved.

Virtual modelling of components of a production system as the tool of lean engineering

NASA Astrophysics Data System (ADS)

Monica, Z.

2015-11-01

Between the most effective techniques of manufacturing management is considered the Lean Engineering. The term “lean engineering” was created by Japanese manufacturers. The high efficiency of this method resulted in a meaningful growth in concern in the philosophy of Lean among European companies, and consequently the use of its European markets. Lean philosophy is an approach to manufacturing to minimize the use of all resources, including time. These are resources that are used in the company for a variety of activities. This implies, first identify and then eliminate activities which does not generate added value in the field of design, manufacturing, supply chain management, and customer relations. The producers of these principles not only employ teams multi-professional employees at all levels of the organization, but also use a more automated machines to produce large quantities of products with a high degree of diversity. Lean Engineering is to use a number of principles and practical guidelines that allow you to reduce costs by eliminating absolute extravagance, and also simplification of all manufacturing processes and maintenance. Nowadays it could be applied the powerful engineering programs to realize the concept of Lean Engineering. They could be described using the term CAD/CAM/CAE. They consist of completely different packages for both the design of elements, as well process design. Their common feature is generally considered with their application area. They are used for computer programs assisting the design, development and manufacturing phases of a manufacturing process. The idea of the presented work is to use the Siemens NX software for aiding the process of Lean Engineering system creating. The investigated system is a robotized workcell. In the NX system are created the components of the designed workcell such as machine tools, as industrial robot, as conveyors and buffers. The system let to functionally link these components to simulate the work process and to introduce the rules of Lean Engineering. The purpose is also to determine the rules of Lean designing in such advanced design and simulation environments.

Application of CAD/CAE class systems to aerodynamic analysis of electric race cars

NASA Astrophysics Data System (ADS)

Grabowski, L.; Baier, A.; Buchacz, A.; Majzner, M.; Sobek, M.

2015-11-01

Aerodynamics is one of the most important factors which influence on every aspect of a design of a car and car driving parameters. The biggest influence aerodynamics has on design of a shape of a race car body, especially when the main objective of the race is the longest distance driven in period of time, which can not be achieved without low energy consumption and low drag of a car. Designing shape of the vehicle body that must generate the lowest possible drag force, without compromising the other parameters of the drive. In the article entitled „Application of CAD/CAE class systems to aerodynamic analysis of electric race cars” are being presented problems solved by computer analysis of cars aerodynamics and free form modelling. Analysis have been subjected to existing race car of a Silesian Greenpower Race Team. On a basis of results of analysis of existence of Kammback aerodynamic effect innovative car body were modeled. Afterwards aerodynamic analysis were performed to verify existence of aerodynamic effect for innovative shape and to recognize aerodynamics parameters of the shape. Analysis results in the values of coefficients and aerodynamic drag forces. The resulting drag forces Fx, drag coefficients Cx(Cd) and aerodynamic factors Cx*A allowed to compare all of the shapes to each other. Pressure distribution, air velocities and streams courses were useful in determining aerodynamic features of analyzed shape. For aerodynamic tests was used Ansys Fluent CFD software. In a paper the ways of surface modeling with usage of Realize Shape module and classic surface modeling were presented. For shapes modeling Siemens NX 9.0 software was used. Obtained results were used to estimation of existing shapes and to make appropriate conclusions.

Seneca Compressed Air Energy Storage (CAES) Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2012-11-30

This document provides specifications for the process air compressor for a compressed air storage project, requests a budgetary quote, and provides supporting information, including compressor data, site specific data, water analysis, and Seneca CAES value drivers.

A Study for Adjustable Riding Position of the Innovation Bicycle Design

NASA Astrophysics Data System (ADS)

Huang, Yu-Che; Huang, Tai-Shen

2018-04-01

This research is about the analysis and design of the user in a wheelchair use posture can be changed. So user can through different sitting posture changes to provide different needs, so the folding design patents for the existing data collection and classification, through the analysis of advantages and disadvantages, further to find the innovative design approach. Finally through the multi linkage mechanism system, change the seat, handlebars and rear position, provide different posture context. In order to reduce the cost, this study is designed to integrate the innovation input mechanism, multi linkage system, through the construction of 10 joints and degrees of freedom of the bicycle frame. Then use 3D software to design of bicycle the size of the frame of innovation, through the three-dimensional CAD model to simulate the mechanism between movement and interference, and to evaluate the 3D The virtual prototype can meet the requirement. It will also enable CAE to analyze and determine the strength and the safety of the bicycle frame structure of ANSYS11.0 stress. Finally, we have integrated design through CAID to make a product appearance, the focus of research is mainly a study of CAD, CAE, CAID integration the production and the completion of a prototype.

Research and Application of Autodesk Fusion360 in Industrial Design

NASA Astrophysics Data System (ADS)

Song, P. P.; Qi, Y. M.; Cai, D. C.

2018-05-01

In 2016, Fusion 360, a productintroduced byAutodesk and integrating industrial design, structural design, mechanical simulation, and CAM, turns out a design platform supportingcollaboration and sharing both cross-platform and via the cloud. In previous products, design and manufacturing use to be isolated. In the course of design, research and development, the communication between designers and engineers used to go on through different software products, tool commands, and even industry terms. Moreover, difficulty also lies with the communication between design thoughts and machining strategies. Naturally, a difficult product design and R & D process would trigger a noticeable gap between the design model and the actual product. A complete product development process tends to cover several major areas, such as industrial design, mechanical design, rendering and animation, computer aided emulation (CAE), and computer aided manufacturing (CAM). Fusion 360, a perfect design solving the technical problems of cross-platform data exchange, realizes the effective control of cross-regional collaboration and presents an overview of collaboration and breaks the barriers between art and manufacturing, andblocks between design and processing. The “Eco-development of Fusion360 Industrial Chain” is both a significant means to and an inevitable trend forthe manufacturers and industrial designers to carry out innovation in China.

Integration of the virtual model of a Stewart platform with the avatar of a vehicle in a virtual reality

NASA Astrophysics Data System (ADS)

Herbuś, K.; Ociepka, P.

2016-08-01

The development of methods of computer aided design and engineering allows conducting virtual tests, among others concerning motion simulation of technical means. The paper presents a method of integrating an object in the form of a virtual model of a Stewart platform with an avatar of a vehicle moving in a virtual environment. The area of the problem includes issues related to the problem of fidelity of mapping the work of the analyzed technical mean. The main object of investigations is a 3D model of a Stewart platform, which is a subsystem of the simulator designated for driving learning for disabled persons. The analyzed model of the platform, prepared for motion simulation, was created in the “Motion Simulation” module of a CAD/CAE class system Siemens PLM NX. Whereas the virtual environment, in which the moves the avatar of the passenger car, was elaborated in a VR class system EON Studio. The element integrating both of the mentioned software environments is a developed application that reads information from the virtual reality (VR) concerning the current position of the car avatar. Then, basing on the accepted algorithm, it sends control signals to respective joints of the model of the Stewart platform (CAD).

Effects of process parameters in plastic, metal, and ceramic injection molding processes

NASA Astrophysics Data System (ADS)

Lee, Shi W.; Ahn, Seokyoung; Whang, Chul Jin; Park, Seong Jin; Atre, Sundar V.; Kim, Jookwon; German, Randall M.

2011-09-01

Plastic injection molding has been widely used in the past and is a dominant forming approach today. As the customer demands require materials with better engineering properties that were not feasible with polymers, powder injection molding with metal and ceramic powders has received considerable attention in recent decades. To better understand the differences in the plastic injection molding, metal injection molding, and ceramic injection molding, the effects of the core process parameters on the process performances has been studied using the state-of-the-art computer-aided engineering (CAE) design tool, PIMSolver® The design of experiments has been conducted using the Taguchi method to obtain the relative contributions of various process parameters onto the successful operations.

Prevalence and pattern of abnormal myocardial perfusion in patients with isolated coronary artery ectasia: study by 99mTc-sestamibi radionuclide scintigraphy.

PubMed

Ismail, Ahmed M; Rayan, Mona; Adel, Amr; Demerdash, Salah; Atef, Mohamed; Abdallah, Mohamed; Nammas, Wail

2014-02-01

We explored the prevalence and pattern of abnormal myocardial perfusion in patients with isolated coronary artery ectasia (CAE), as demonstrated by (99m)Tc-sestamibi scintigraphy. Prospectively, we enrolled 35 patients with angiographically documented CAE and no significant coronary obstruction, who underwent elective coronary angiography. Patients underwent Stress-rest (99m)Tc-sestamibi scintigraphy within 4 days of coronary angiography. They were divided into 2 groups: group I: with normal perfusion scan; and group II: with reversible perfusion defects. The mean age was 49.6 ± 6.9 years; 34 (97.1 %) were males. Seventy-nine (75.2 %) arteries were affected by CAE. Among 79 arteries affected by CAE, affection was diffuse in 37 (46.8 %). Thirteen (37.1 %) patients had normal perfusion scan (group I), whereas 22 (62.9 %) had reversible perfusion defects (group II). Among 22 patients with reversible perfusion defects, 20 (90.9 %) had mild and 2 (9.1 %) had moderate ischemia. Among 49 myocardial segments with reversible perfusion defects, 22 (44.9 %) were basal, 18 (36.7 %) mid-, and 9 (18.4 %) apical segments. Diffuse CAE was significantly more prevalent in group II versus group I, in all 3 major coronary arteries (p < 0.05 for all). In patients with isolated CAE who underwent elective coronary angiography, reversible perfusion defects demonstrated by (99m)Tc-sestamibi scintigraphy were rather prevalent, mostly mild, more likely to affect the basal and mid-segments of the myocardium, and more frequently associated with diffuse ectasia.

Dredging Operations Technical Support Program: Engineering Design and Environmental Assessment of Dredged Material Overflow from Hydraulically Filled Hopper Barges in Mobile Bay, Alabama

DTIC Science & Technology

1990-09-01

turbid estuarine habitats such as Mobile Bay are very tolerant of moderately high concentrations of suspended sediments and thin layers of sediment...GULF OF MEXIC BAYOU 4M 2CAE SI2LTK Fiur 3. DsrbuinoAedmnTyesi oie a fo IsphordingLT anCLmb190 PART III: DREDGING EQUIPMENT AND OPERATIONAL TECHNIQUES...increase in ambient turbidity was noted. Water samples were collected at surface, middepth, and bottom. The sampling boats proceeded across their

3D printing of soft-matter to open a new era of soft-matter MEMS/robotics (Conference Presentation)

NASA Astrophysics Data System (ADS)

Furukawa, Hidemitsu

2017-04-01

3D printing technology is becoming useful and applicable by the progress of information and communication technology (ICT). It means 3D printer is a kind of useful robot for additive manufacturing and is controlled by computer with human-friendly software. Once user starts to use 3D printing of soft-matter, one can immediately understand computer-aided design (CAD) and engineering (CAE) technology will be more important and applicable for soft-matter systems. User can easily design soft-matter objects and 3D-print them. User can easily apply 3D-printed soft-matter objects to develop new research and application on MEMS and robotics. Here we introduce the recent progress of 3D printing (i.e. additive manufacturing), especially focusing on our 3D gel printing. We are trying to develop new advanced research and applications of 3D gel printer, including GEL-MECHANICS, GEL-PHOTONICS, and GEL-ROBOTICS. In the gel-mechanics, we are developing new gel materials for mechanical engineering. Some gels have high-mechanical strength and shape memory properties. In the gel-photonics. We are applying our original characterizing system, named `Scanning Microscopic Light Scattering (SMILS)', to analyze 3D printed gel materials. In the gel-robotics, we focus on 3D printing of soft parts for soft-robotics made form gel materials, like gel finger. Also we are challenging to apply 3D gel printing to start new company, to innovate new businesses in county side, and to create new 3D-printed foods.

Parsley extract inhibits in vitro and ex vivo platelet aggregation and prolongs bleeding time in rats.

PubMed

Gadi, Dounia; Bnouham, Mohamed; Aziz, Mohammed; Ziyyat, Abderrahim; Legssyer, Abdelkhaleq; Legrand, Chantal; Lafeve, Françoise Fauvel; Mekhfi, Hassane

2009-08-17

Many cardiovascular diseases are associated with an increase in blood platelet activity. In Morocco, parsley (Petroselinum crispum, Apiaceae) is one of the medicinal herbs used to treat cardiovascular diseases such as arterial hypertension. In this study, crude aqueous extract (CAE) of parsley was evaluated for its anti-platelet activity in experimental animals on platelet aggregation in vitro and ex vivo; and on bleeding time in vivo. The in vitro aggregation was monitored after pre-incubation of platelets with CAE. The bleeding time and ex vivo aggregation were performed after oral treatment. CAE inhibited dose dependently platelet aggregation in vitro induced by thrombin, ADP, collagen and epinephrine. The oral administration of CAE (3g/kg) inhibited significantly (p<0.001) platelet aggregation ex vivo and prolonged bleeding time (p<0.001) without changes in the platelet amount. The prolongation of bleeding time by CAE may be attributed to the observed inhibition of platelet aggregation. These effects could be related in part to the polyphenolic compounds present in the extract. These results support the hypothesis that the dietary intake of parsley may be benefit in the normalization of platelet hyperactivation, in the nutritional prevention of cardiovascular diseases and are potentially interesting in the development of new prevention strategies.

Geotechnical Feasibility Analysis of Compressed Air Energy Storage (CAES) in Bedded Salt Formations: a Case Study in Huai'an City, China

NASA Astrophysics Data System (ADS)

Zhang, Guimin; Li, Yinping; Daemen, Jaak J. K.; Yang, Chunhe; Wu, Yu; Zhang, Kai; Chen, Yanlong

2015-09-01

The lower reaches of the Yangtze River is one of the most developed regions in China. It is desirable to build compressed air energy storage (CAES) power plants in this area to ensure the safety, stability, and economic operation of the power network. Geotechnical feasibility analysis was carried out for CAES in impure bedded salt formations in Huai'an City, China, located in this region. First, geological investigation revealed that the salt groups in the Zhangxing Block meet the basic geological conditions for CAES storage, even though the possible unfavorable characteristics of the salt formations include bedding and different percentages of impurities. Second, mechanical tests were carried out to determine the mechanical characteristics of the bedded salt formations. It is encouraging that the samples did not fail even when they had undergone large creep deformation. Finally, numerical simulation was performed to evaluate the stability and volume shrinkage of the CAES under the following conditions: the shape of a single cavern is that of a pear; the width of the pillar is adopted as two times the largest diameter; three regular operating patterns were adopted for two operating caverns (internal pressure 9-10.5 MPa, 10-11.5 MPa, and 11-12.5 MPa), while the other two were kept at high pressure (internal pressure 10.5, 11.5, and 12.5 MPa) as backups; an emergency operating pattern in which two operating caverns were kept at atmospheric pressure (0.1 MPa) for emergency while the backups were under operation (9-10.5 MPa), simulated for 12 months at the beginning of the 5th year. The results of the analysis for the plastic zone, displacement, and volume shrinkage support the feasibility of the construction of an underground CAES power station.

Thermodynamic Performance and Cost Optimization of a Novel Hybrid Thermal-Compressed Air Energy Storage System Design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Houssainy, Sammy; Janbozorgi, Mohammad; Kavehpour, Pirouz

Compressed Air Energy Storage (CAES) can potentially allow renewable energy sources to meet electricity demands as reliably as coal-fired power plants. However, conventional CAES systems rely on the combustion of natural gas, require large storage volumes, and operate at high pressures, which possess inherent problems such as high costs, strict geological locations, and the production of greenhouse gas emissions. A novel and patented hybrid thermal-compressed air energy storage (HT-CAES) design is presented which allows a portion of the available energy, from the grid or renewable sources, to operate a compressor and the remainder to be converted and stored in themore » form of heat, through joule heating in a sensible thermal storage medium. The HT-CAES design incudes a turbocharger unit that provides supplementary mass flow rate alongside the air storage. The hybrid design and the addition of a turbocharger have the beneficial effect of mitigating the shortcomings of conventional CAES systems and its derivatives by eliminating combustion emissions and reducing storage volumes, operating pressures, and costs. Storage efficiency and cost are the two key factors, which upon integration with renewable energies would allow the sources to operate as independent forms of sustainable energy. The potential of the HT-CAES design is illustrated through a thermodynamic optimization study, which outlines key variables that have a major impact on the performance and economics of the storage system. The optimization analysis quantifies the required distribution of energy between thermal and compressed air energy storage, for maximum efficiency, and for minimum cost. This study provides a roundtrip energy and exergy efficiency map of the storage system and illustrates a trade off that exists between its capital cost and performance.« less

Validation of Material Models For Automotive Carbon Fiber Composite Structures Via Physical And Crash Testing (VMM Composites Project)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coppola, Anthony; Faruque, Omar; Truskin, James F

As automotive fuel economy requirements increase, the push for reducing overall vehicle weight will likely include the consideration of materials that have not previously been part of mainstream vehicle design and manufacturing, including carbon fiber composites. Vehicle manufacturers currently rely on computer-aided engineering (CAE) methods as part of the design and development process, so going forward, the ability to accurately and predictably model carbon fiber composites will be necessary. If composites are to be used for structural components, this need applies to both, crash and quasi-static modeling. This final report covers the results of a five-year, $6.89M, 50% cost-shared researchmore » project between Department of Energy (DOE) and the US Advanced Materials Partnership (USAMP) under Cooperative Agreement DE-EE-0005661 known as “Validation of Material Models for Automotive Carbon Fiber Composite Structures Via Physical and Crash Testing (VMM).” The objective of the VMM Composites Project was to validate and assess the ability of physics-based material models to predict crash performance of automotive primary load-carrying carbon fiber composite structures. Simulation material models that were evaluated included micro-mechanics based meso-scale models developed by the University of Michigan (UM) and micro-plane models by Northwestern University (NWU) under previous collaborations with the DOE and Automotive Composites Consortium/USAMP, as well as five commercial crash codes: LS-DYNA, RADIOSS, VPS/PAM-CRASH, Abaqus, and GENOA-MCQ. CAE predictions obtained from seven organizations were compared with experimental results from quasi-static testing and dynamic crash testing of a thermoset carbon fiber composite front-bumper and crush-can (FBCC) system gathered under multiple loading conditions. This FBCC design was developed to demonstrate progressive crush, virtual simulation, tooling, fabrication, assembly, non-destructive evaluation and crash testing advances in order to assess the correlation of the predicted results to the physical tests. The FBCC was developed to meet a goal of 30-35% mass reduction while aiming for equivalent energy absorption as a steel component for which baseline experimental results were obtained from testing in the same crash modes. The project also evaluated crash performance of thermoplastic composite structures fabricated from commercial prepreg materials and low cost carbon fiber sourced from Oak Ridge National Laboratory. The VMM Project determined that no set of predictions from a CAE supplier were found to be universally accurate among all the six crash modes evaluated. In general, crash modes that were most dependent on the properties of the prepreg were more accurate than those that were dependent on the behavior of the joints. The project found that current CAE modeling methods or best practices for carbon fiber composites have not achieved standardization, and accuracy of CAE is highly reliant on the experience of its users. Coupon tests alone are not sufficient to develop an accurate material model, but it is necessary to bridge the gap between the coupon data and performance of the actual structure with a series of subcomponent level tests. Much of the unreliability of the predictions can be attributed to shortcomings in our ability to mathematically link the effects of manufacturing and material variability into the material models. This is a subject of ongoing research in the industry. The final report is organized by key technical tasks to describe how the validation project developed, modeled and compared crash data obtained on the composite FBCC to the multiple sets of CAE predictions. Highlights of the report include a discussion of the quantitative comparison between predictions and experimental data, as well as an in-depth discussion of remaining technological gaps that exist in the industry, which are intended to spur innovations and improvements in CAE technology.« less

PLM in the context of the maritime virtual education

NASA Astrophysics Data System (ADS)

Raicu, Alexandra; Oanta, Emil M.

2016-12-01

This paper presents new approaches regarding the use of Product Lifecycle Management concept to achieve knowledge integration of the academic disciplines in the maritime education context. The philosophy of the educational system is now changing faster worldwide and it is in a continuous developing process. There is a demand to develop modern educational facilities for CAD/CAE/CAM training of the future maritime engineers, which offers collaborative environments between the academic disciplines and the teachers. It is well known that the students must understand the importance of the connectivity between the academic disciplines and the computer aided methods to interface them. Thus, besides the basic knowledge and competences acquired from the CAD courses, students learn how to increase the design productivity, to create a parametric design, the original instruments of automatic design, 3D printing methods, how to interface the CAD/CAE/CAM applications. As an example, the Strength of Materials discipline briefly presents alternate computer aided methods to compute the geometrical characteristics of the cross sections using the CAD geometry, creation the free body diagrams and presentation the deflected shapes of various educational models, including the rotational effect when the forces are not applied in the shear center, using the results of the FEM applications. During the computer aided engineering academic disciplines, after the students design and analyze a virtual 3D model they can convert it into a physical object using 3D printing method. Constanta Maritime University offers a full understanding of the concept of Product Lifecycle Management, collaborative creation, management and dissemination.

Integration and Control of a Battery Balancing System

DTIC Science & Technology

2013-12-01

2. Energy storage comparisons. From [2]. • Storage Technologies Pumped Storage CAES Flow Batteries: PSB VRB ZnBr Metal-Air NaS LHon Ni...Storage Technologies Pumped Storage CAES Flow Batteries: PSB VRB ZnBr Metal-Air NaS LHon Ni-Cd Other Advanced Batteries Lead-Acid

Positive grid corrosion elongation analysis using CAE with corrosion deformation transformed into thermal phenomenon

NASA Astrophysics Data System (ADS)

Mukaitani, Ichiroh; Hayashi, Koji; Shimoura, Ichiro; Takemasa, Arihiko; Takahashi, Isamu; Tsubakino, Harushige

Valve-regulated lead-acid (VRLA) batteries have been commercially available for more than 20 years and have been enthusiastically embraced by users of uninterruptible power supplies (UPS) because of the anticipated reduction in installation and operating costs, smaller footprint and fewer environmental concerns. In Japan, communication networks are demanding reduced costs and longer life from their batteries. Among the factors limiting the life of VRLA batteries, the corrosion of positive grid material has been proven to cause elongation of the plates, loss of electrical contact and shorter lifetime. The content of Sn is also a key factor and addition of Sn in the grid alloy results in better performance in creep resistance, tensile strength and corrosion resistance [R. David Prenagaman, The Battery Man, vol. 39, September 1997, p. 16. I. Mukaitani, T. Sakamoto, T. Kikuoka, Y. Yamaguchi, H. Tsubakino, Proceedings of the 40th Battery Symposium in Japan, 1999, p. 99]. A key point is what the ratio of Sn to Ca should be, since too much Sn may lead to even worse elongation of the plates [I. Mukaitani, T. Sakamoto, T. Kikuoka, Y. Yamaguchi, H. Tsubakino, Proceedings of the 40th Battery Symposium in Japan, 1999, p. 99]. We have determined that microstructure control with a composition of lead-calcium-tin (Pb-Ca-Sn) alloy is optimal for better performance of the plates [I. Mukaitani, T. Sakamoto, T. Kikuoka, Y. Yamaguchi, H. Tsubakino, Proceedings of the 40th Battery Symposium in Japan, 1999, p. 99]. We developed a "simulation of current collector corrosion elongation" which is a technique of estimating corrosion elongation from the current collector design [I. Mukaitani, K. Hayashi, I. Shimoura, H. Takabayashi, M. Terada, A. Takemasa, I. Takahashi, K. Okamoto, Proceedings of the 44th Battery Symposium in Japan, 2003, p. 652]. Corrosion elongation occurs as the corrosion material layer grows out of the current collector metal. We resolved this problem using generally CAD software " Solid Works" and computer aided engineering (CAE) software " ANSYS" with corrosion elongation transformed into thermal elongation. We established a current collector corrosion elongation forecast and found that the microstructure controlled the Pb-Ca-Sn alloy; thus newly designed VRLA batteries (MU-series [A. Takemasa, I. Mukaitani, Y. Yoshiyama, K. Fukui, T. Sakamoto, T. Kuwano, M. Fukuda, H. Misaki, K. Uwatari, Shin-Kobe Technical Report 9 (1999) 11] for telecommunication and LL-series [H. Takabayashi, T. Shibahara, Y. Mastuda, K. Fukui, S. Hazui, Y. Matsumura, S. Kondo, Shin-Kobe Tech. Rep. 11 (2001) 35] for electric energy storage) which are lightweight and have long life are introduced here.

Characterization of the metallo-dependent amidohydrolases responsible for "auxiliary" leucinyl removal in the biosynthesis of 2,2'-bipyridine antibiotics.

PubMed

Chen, Ming; Pang, Bo; Du, Ya-Nan; Zhang, Yi-Peng; Liu, Wen

2017-06-01

2,2'-Bipyridine (2,2'-BiPy) is an attractive core structure present in a number of biologically active natural products, including the structurally related antibiotics caerulomycins (CAEs) and collismycins (COLs). Their biosynthetic pathways share a similar key 2,2'-BiPy-l-leucine intermediate, which is desulfurated or sulfurated at C5, arises from a polyketide synthase/nonribosomal peptide synthetase hybrid assembly line. Focusing on the common off-line modification steps, we here report that the removal of the "auxiliary" l-leucine residue relies on the metallo-dependent amidohydrolase activity of CaeD or ColD. This activity leads to the production of similar 2,2'-BiPy carboxylate products that then receive an oxime functionality that is characteristic for both CAEs and COLs. Unlike many metallo-dependent amidohydrolase superfamily proteins that have been previously reported, these proteins (particularly CaeD) exhibited a strong zinc ion-binding capacity that was proven by site-specific mutagenesis studies to be essential to proteolytic activity. The kinetics of the conversions that respectively involve CaeD and ColD were analyzed, showing the differences in the efficiency and substrate specificity of these two proteins. These findings would generate interest in the metallo-dependent amidohydrolase superfamily proteins that are involved in the biosynthesis of bioactive natural products.

The significance of selegiline/(-)-deprenyl after 50 years in research and therapy (1965-2015).

PubMed

Miklya, I

2016-11-01

Deprenyl/Selegiline (DEP), created by Joseph Knoll in the 1960s, registered in more than 60 countries to treat Parkinson's disease, Alzheimer's disease, major depressive disorder; and used as an anti-aging drug, achieved its place in research and therapy as the first selective inhibitor of B-type monoamine oxidase (MAO-B). The demonstration that the DEP analog (-)-1-phenyl-2-propylaminopentane devoid of MAO inhibitory property, enhanced like DEP the activity of the catecholaminergic brain engine revealed that this effect is unrelated to the selective inhibition of MAO-B. β-Phenylethylamine (PEA), the important trace-amine in the mammalian brain, is known to be a releaser of catecholamines. Amphetamine and methamphetamine, the best known synthetic PEA derivatives are also releasers of catecholamines like their parent compound. DEP is a unique synthetic PEA derivative devoid of the catecholamine releasing property. As the releasing effect conceals the catecholaminergic activity enhancer (CAE) effect, it remained undiscovered until DEP uncovered that PEA is a natural CAE substance; and only releases catecholamines in high concentration. Discovering that tryptamine is a natural enhancer of catecholaminergic and serotonergic neurons catalyzed the development of R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane (BPAP); the most potent and selective enhancer substance, and it exerts its enhancer effect in 0.0001 mg kg -1 . DEP and BPAP initiated an analysis of the enhancer regulation in the mammalian brain. Studies regarding the nature of the enhancer regulation revealed that this regulation is enhanced after weaning and sex hormones return it to the pre-weaning level. Thus, sex hormones elicit the transition of the developmental phase of life into the post-developmental, downhill (aging) period. The aging-related, slow decline in the enhancer regulation of the catecholaminergic brain engine, the main activator of the cortex, is the prime factor of brain aging. The enhancer regulation's decay in the most rapidly aging dopaminergic system is, for example, mainly responsible for the decline in learning ability and sexual activity over time. According to the Knoll concept, based on two longevity studies performed on male rats, to keep the catecholaminergic brain engine, from the beginning of the downhill period of life, via the administration of a small daily dose of a CAE substance (presently DEP is the only available drug) on a higher activity level, thus to fight against the physiological aging-related slow decay of the catecholaminergic system, is a suitable anti-aging therapy. As our present knowledge regarding the enhancer regulation in the mammalian brain is like seeing a peak of an iceberg, the future of this new line of brain research looks promising from both theoretical and practical aspects.

Optimization of Compressor Mounting Bracket of a Passenger Car

NASA Astrophysics Data System (ADS)

Kalsi, Sachin; Singh, Daljeet; Saini, J. S.

2018-05-01

In the present work, the CAE tools are used for the optimization of the compressor mounting bracket used in an automobile. Both static and dynamic analysis is done for the bracket. With the objective to minimize the mass and increase the stiffness of the bracket, the new design is optimized using shape and topology optimization techniques. The optimized design given by CAE tool is then validated experimentally. The new design results in lower level of vibrations, contribute to lower mass along with lesser cost which is effective in air conditioning system as well as the efficiency of a vehicle. The results given by CAE tool had a very good correlation with the experimental results.

A Fully Automated and Robust Method to Incorporate Stamping Data in Crash, NVH and Durability Analysis

NASA Astrophysics Data System (ADS)

Palaniswamy, Hariharasudhan; Kanthadai, Narayan; Roy, Subir; Beauchesne, Erwan

2011-08-01

Crash, NVH (Noise, Vibration, Harshness), and durability analysis are commonly deployed in structural CAE analysis for mechanical design of components especially in the automotive industry. Components manufactured by stamping constitute a major portion of the automotive structure. In CAE analysis they are modeled at a nominal state with uniform thickness and no residual stresses and strains. However, in reality the stamped components have non-uniformly distributed thickness and residual stresses and strains resulting from stamping. It is essential to consider the stamping information in CAE analysis to accurately model the behavior of the sheet metal structures under different loading conditions. Especially with the current emphasis on weight reduction by replacing conventional steels with aluminum and advanced high strength steels it is imperative to avoid over design. Considering this growing need in industry, a highly automated and robust method has been integrated within Altair Hyperworks® to initialize sheet metal components in CAE models with stamping data. This paper demonstrates this new feature and the influence of stamping data for a full car frontal crash analysis.

Liquid toroidal drop under uniform electric field

NASA Astrophysics Data System (ADS)

Zabarankin, Michael

2017-06-01

The problem of a stationary liquid toroidal drop freely suspended in another fluid and subjected to an electric field uniform at infinity is addressed analytically. Taylor's discriminating function implies that, when the phases have equal viscosities and are assumed to be slightly conducting (leaky dielectrics), a spherical drop is stationary when Q=(2R2+3R+2)/(7R2), where R and Q are ratios of the phases' electric conductivities and dielectric constants, respectively. This condition holds for any electric capillary number, CaE, that defines the ratio of electric stress to surface tension. Pairam and Fernández-Nieves showed experimentally that, in the absence of external forces (CaE=0), a toroidal drop shrinks towards its centre, and, consequently, the drop can be stationary only for some CaE>0. This work finds Q and CaE such that, under the presence of an electric field and with equal viscosities of the phases, a toroidal drop having major radius ρ and volume 4π/3 is qualitatively stationary-the normal velocity of the drop's interface is minute and the interface coincides visually with a streamline. The found Q and CaE depend on R and ρ, and for large ρ, e.g. ρ≥3, they have simple approximations: Q˜(R2+R+1)/(3R2) and CaE∼3 √{3 π ρ / 2 } (6 ln ⁡ρ +2 ln ⁡[96 π ]-9 )/ (12 ln ⁡ρ +4 ln ⁡[96 π ]-17 ) (R+1 ) 2/ (R-1 ) 2.

Secure Distributed Detection under Energy Constraint in IoT-Oriented Sensor Networks.

PubMed

Zhang, Guomei; Sun, Hao

2016-12-16

We study the secure distributed detection problems under energy constraint for IoT-oriented sensor networks. The conventional channel-aware encryption (CAE) is an efficient physical-layer secure distributed detection scheme in light of its energy efficiency, good scalability and robustness over diverse eavesdropping scenarios. However, in the CAE scheme, it remains an open problem of how to optimize the key thresholds for the estimated channel gain, which are used to determine the sensor's reporting action. Moreover, the CAE scheme does not jointly consider the accuracy of local detection results in determining whether to stay dormant for a sensor. To solve these problems, we first analyze the error probability and derive the optimal thresholds in the CAE scheme under a specified energy constraint. These results build a convenient mathematic framework for our further innovative design. Under this framework, we propose a hybrid secure distributed detection scheme. Our proposal can satisfy the energy constraint by keeping some sensors inactive according to the local detection confidence level, which is characterized by likelihood ratio. In the meanwhile, the security is guaranteed through randomly flipping the local decisions forwarded to the fusion center based on the channel amplitude. We further optimize the key parameters of our hybrid scheme, including two local decision thresholds and one channel comparison threshold. Performance evaluation results demonstrate that our hybrid scheme outperforms the CAE under stringent energy constraints, especially in the high signal-to-noise ratio scenario, while the security is still assured.

Arsenic methylation capability and hypertension risk in subjects living in arseniasis-hyperendemic areas in southwestern Taiwan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Y.-K.; Tseng, C.-H.; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

Background: Cumulative arsenic exposure (CAE) from drinking water has been shown to be associated with hypertension in a dose-response pattern. This study further explored the association between arsenic methylation capability and hypertension risk among residents of arseniasis-hyperendemic areas in Taiwan considering the effect of CAE and other potential confounders. Method: There were 871 subjects (488 women and 383 men) and among them 372 were diagnosed as having hypertension based on a positive history or measured systolic blood pressure {>=} 140 mm Hg and/or diastolic blood pressure {>=} 90 mm Hg. Urinary arsenic species were determined by high-performance liquid chromatography-hydride generatormore » and atomic absorption spectrometry. Primary arsenic methylation index [PMI, defined as monomethylarsonic acid (MMA{sup V}) divided by (As{sup III} + As{sup V})] and secondary arsenic methylation index (SMI, defined as dimethylarsinic acid divided by MMA{sup V}) were used as indicators for arsenic methylation capability. Results: The level of urinary arsenic was still significantly correlated with cumulative arsenic exposure (CAE) calculated from a questionnaire interview (p = 0.02) even after the residents stopped drinking the artesian well water for 2-3 decades. Hypertensive subjects had higher percentages of MMA{sup V} and lower SMI than subjects without hypertension. However, subjects having CAE > 0 mg/L-year had higher hypertension risk than those who had CAE = 0 mg/L-year disregard a high or low methylation index. Conclusion: Inefficient arsenic methylation ability may be related with hypertension risk.« less

Secure Distributed Detection under Energy Constraint in IoT-Oriented Sensor Networks

PubMed Central

Zhang, Guomei; Sun, Hao

2016-01-01

We study the secure distributed detection problems under energy constraint for IoT-oriented sensor networks. The conventional channel-aware encryption (CAE) is an efficient physical-layer secure distributed detection scheme in light of its energy efficiency, good scalability and robustness over diverse eavesdropping scenarios. However, in the CAE scheme, it remains an open problem of how to optimize the key thresholds for the estimated channel gain, which are used to determine the sensor’s reporting action. Moreover, the CAE scheme does not jointly consider the accuracy of local detection results in determining whether to stay dormant for a sensor. To solve these problems, we first analyze the error probability and derive the optimal thresholds in the CAE scheme under a specified energy constraint. These results build a convenient mathematic framework for our further innovative design. Under this framework, we propose a hybrid secure distributed detection scheme. Our proposal can satisfy the energy constraint by keeping some sensors inactive according to the local detection confidence level, which is characterized by likelihood ratio. In the meanwhile, the security is guaranteed through randomly flipping the local decisions forwarded to the fusion center based on the channel amplitude. We further optimize the key parameters of our hybrid scheme, including two local decision thresholds and one channel comparison threshold. Performance evaluation results demonstrate that our hybrid scheme outperforms the CAE under stringent energy constraints, especially in the high signal-to-noise ratio scenario, while the security is still assured. PMID:27999282

Software Engineering Guidebook

NASA Technical Reports Server (NTRS)

Connell, John; Wenneson, Greg

1993-01-01

The Software Engineering Guidebook describes SEPG (Software Engineering Process Group) supported processes and techniques for engineering quality software in NASA environments. Three process models are supported: structured, object-oriented, and evolutionary rapid-prototyping. The guidebook covers software life-cycles, engineering, assurance, and configuration management. The guidebook is written for managers and engineers who manage, develop, enhance, and/or maintain software under the Computer Software Services Contract.

Studying Coxiella burnetii Type IV Substrates in the Yeast Saccharomyces cerevisiae: Focus on Subcellular Localization and Protein Aggregation.

PubMed

Rodríguez-Escudero, María; Cid, Víctor J; Molina, María; Schulze-Luehrmann, Jan; Lührmann, Anja; Rodríguez-Escudero, Isabel

2016-01-01

Coxiella burnetii is a Gram-negative obligate parasitic bacterium that causes the disease Q-fever in humans. To establish its intracellular niche, it utilizes the Icm/Dot type IVB secretion system (T4BSS) to inject protein effectors into the host cell cytoplasm. The host targets of most cognate and candidate T4BSS-translocated effectors remain obscure. We used the yeast Saccharomyces cerevisiae as a model to express and study six C. burnetii effectors, namely AnkA, AnkB, AnkF, CBU0077, CaeA and CaeB, in search for clues about their role in C. burnetii virulence. When ectopically expressed in HeLa cells, these effectors displayed distinct subcellular localizations. Accordingly, GFP fusions of these proteins produced in yeast also decorated distinct compartments, and most of them altered cell growth. CaeA was ubiquitinated both in yeast and mammalian cells and, in S. cerevisiae, accumulated at juxtanuclear quality-control compartments (JUNQs) and insoluble protein deposits (IPODs), characteristic of aggregative or misfolded proteins. AnkA, which was not ubiquitinated, accumulated exclusively at the IPOD. CaeA, but not AnkA or the other effectors, caused oxidative damage in yeast. We discuss that CaeA and AnkA behavior in yeast may rather reflect misfolding than recognition of conserved targets in the heterologous system. In contrast, CBU0077 accumulated at vacuolar membranes and abnormal ER extensions, suggesting that it interferes with vesicular traffic, whereas AnkB associated with the yeast nucleolus. Both effectors shared common localization features in HeLa and yeast cells. Our results support the idea that C. burnetii T4BSS effectors manipulate multiple host cell targets, which can be conserved in higher and lower eukaryotic cells. However, the behavior of CaeA and AnkA prompt us to conclude that heterologous protein aggregation and proteostatic stress can be a limitation to be considered when using the yeast model to assess the function of bacterial effectors.

Studying Coxiella burnetii Type IV Substrates in the Yeast Saccharomyces cerevisiae: Focus on Subcellular Localization and Protein Aggregation

PubMed Central

Rodríguez-Escudero, María; Cid, Víctor J.; Molina, María; Schulze-Luehrmann, Jan; Lührmann, Anja; Rodríguez-Escudero, Isabel

2016-01-01

Coxiella burnetii is a Gram-negative obligate parasitic bacterium that causes the disease Q-fever in humans. To establish its intracellular niche, it utilizes the Icm/Dot type IVB secretion system (T4BSS) to inject protein effectors into the host cell cytoplasm. The host targets of most cognate and candidate T4BSS-translocated effectors remain obscure. We used the yeast Saccharomyces cerevisiae as a model to express and study six C. burnetii effectors, namely AnkA, AnkB, AnkF, CBU0077, CaeA and CaeB, in search for clues about their role in C. burnetii virulence. When ectopically expressed in HeLa cells, these effectors displayed distinct subcellular localizations. Accordingly, GFP fusions of these proteins produced in yeast also decorated distinct compartments, and most of them altered cell growth. CaeA was ubiquitinated both in yeast and mammalian cells and, in S. cerevisiae, accumulated at juxtanuclear quality-control compartments (JUNQs) and insoluble protein deposits (IPODs), characteristic of aggregative or misfolded proteins. AnkA, which was not ubiquitinated, accumulated exclusively at the IPOD. CaeA, but not AnkA or the other effectors, caused oxidative damage in yeast. We discuss that CaeA and AnkA behavior in yeast may rather reflect misfolding than recognition of conserved targets in the heterologous system. In contrast, CBU0077 accumulated at vacuolar membranes and abnormal ER extensions, suggesting that it interferes with vesicular traffic, whereas AnkB associated with the yeast nucleolus. Both effectors shared common localization features in HeLa and yeast cells. Our results support the idea that C. burnetii T4BSS effectors manipulate multiple host cell targets, which can be conserved in higher and lower eukaryotic cells. However, the behavior of CaeA and AnkA prompt us to conclude that heterologous protein aggregation and proteostatic stress can be a limitation to be considered when using the yeast model to assess the function of bacterial effectors. PMID:26821324

Preoperative platelet transfusions to reverse antiplatelet therapy for urgent non-cardiac surgery: an observational cohort study.

PubMed

Baschin, M; Selleng, S; Hummel, A; Diedrich, S; Schroeder, H W; Kohlmann, T; Westphal, A; Greinacher, A; Thiele, T

2018-04-01

Essentials An increasing number of patients requiring surgery receive antiplatelet therapy (APT). We analyzed 181 patients receiving presurgery platelet transfusions to reverse APT. No coronary thrombosis occurred after platelet transfusion. This justifies a prospective trial to test preoperative platelet transfusions to reverse APT. Background Patients receiving antiplatelet therapy (APT) have an increased risk of perioperative bleeding and cardiac adverse events (CAE). Preoperative platelet transfusions may reduce the bleeding risk but may also increase the risk of CAE, particularly coronary thrombosis in patients after recent stent implantation. Objectives To analyze the incidence of perioperative CAE and bleeding in patients undergoing non-cardiac surgery using a standardized management of transfusing two platelet concentrates preoperatively and restart of APT within 24-72 h after surgery. Methods A cohort of consecutive patients on APT treated with two platelet concentrates before non-cardiac surgery between January 2012 and December 2014 was retrospectively identified. Patients were stratified by the risk of major adverse cardiac and cerebrovascular events (MACCE). The primary objective was the incidence of CAE (myocardial infarction, acute heart failure and cardiac troponine T increase). Secondary objectives were incidences of other thromboembolic events, bleedings, transfusions and mortality. Results Among 181 patients, 88 received aspirin, 21 clopidogrel and 72 dual APT. MACCE risk was high in 63, moderate in 103 and low in 15 patients; 67 had cardiac stents. Ten patients (5.5%; 95% CI, 3.0-9.9%) developed a CAE (three myocardial infarctions, four cardiac failures and three troponin T increases). None was caused by coronary thrombosis. Surgery-related bleeding occurred in 22 patients (12.2%; 95% CI, 8.2-17.7%), making 12 re-interventions necessary (6.6%; 95% CI, 3.8-11.2%). Conclusion Preoperative platelet transfusions and early restart of APT allowed urgent surgery and did not cause coronary thromboses, but non-thrombotic CAEs and re-bleeding occurred. Randomized trials are warranted to test platelet transfusion against other management strategies. © 2018 International Society on Thrombosis and Haemostasis.

Risk of Cardiac Events Associated With Antidepressant Therapy in Patients With Long QT Syndrome.

PubMed

Wang, Meng; Szepietowska, Barbara; Polonsky, Bronislava; McNitt, Scott; Moss, Arthur J; Zareba, Wojciech; Auerbach, David S

2018-01-15

Patients with long QT syndrome (LQTS) are at a high risk of cardiac events. Many patients with LQTS are treated with antidepressant drugs (ADs). We investigated the LQTS genotype-specific risk of recurrent cardiac arrhythmic events (CAEs) associated with AD therapy. The study included 59 LQT1 and 72 LQT2 patients from the Rochester-based LQTS Registry with corrected QT (QT c ) prolongation and a history of AD therapy. Using multivariate Anderson-Gill models, we estimated the LQTS genotype-specific risk of recurrent CAEs (ventricular tachyarrhythmias, aborted cardiac arrest, or sudden cardiac death) associated with time-dependent ADs. Specifically, we examined the risk associated with all ADs, selective serotonin reuptake inhibitor (SSRI), and ADs classified on the CredibleMeds list (www.CredibleMeds.org) as "Conditional" or "Known risk of Torsades de pointes (TdP)." After adjusting for baseline QT c duration, sex, and time-dependent beta-blocker usage, there was an increased risk of recurrent CAEs associated with ADs in LQT1 patients (hazard ratio = 3.67, 95% confidence interval 1.98-6.82, p < 0.001) but not in LQT2 patients (hazard ratio = 0.89, 95% confidence interval 0.49-1.64, p = 0.716; LQT1 vs LQT2 interaction, p < 0.001). Similarly, LQT1 patients who were on SSRIs or ADs with "Known risk of TdP" had a higher risk of recurrent CAEs than those patients off all ADs, whereas there was no association in LQT2 patients. ADs with "Conditional risk of TdP" were not associated with the risk of recurrent CAEs in any of the groups. In conclusion, the risk of recurrent CAEs associated with time-dependent ADs is higher in LQT1 patients but not in LQT2 patients. Results suggest a LQTS genotype-specific effect of ADs on the risk of arrhythmic events. Copyright © 2017 Elsevier Inc. All rights reserved.

National Combustion Code Validated Against Lean Direct Injection Flow Field Data

NASA Technical Reports Server (NTRS)

Iannetti, Anthony C.

2003-01-01

Most combustion processes have, in some way or another, a recirculating flow field. This recirculation stabilizes the reaction zone, or flame, but an unnecessarily large recirculation zone can result in high nitrogen oxide (NOx) values for combustion systems. The size of this recirculation zone is crucial to the performance of state-of-the-art, low-emissions hardware. If this is a large-scale combustion process, the flow field will probably be turbulent and, therefore, three-dimensional. This research dealt primarily with flow fields resulting from lean direct injection (LDI) concepts, as described in Research & Technology 2001. LDI is a concept that depends heavily on the design of the swirler. The LDI concept has the potential to reduce NOx values from 50 to 70 percent of current values, with good flame stability characteristics. It is cost effective and (hopefully) beneficial to do most of the design work for an LDI swirler using computer-aided design (CAD) and computer-aided engineering (CAE) tools. Computational fluid dynamics (CFD) codes are CAE tools that can calculate three-dimensional flows in complex geometries. However, CFD codes are only beginning to correctly calculate the flow fields for complex devices, and the related combustion models usually remove a large portion of the flow physics.

Simulating the dynamic behavior of chain drive systems by advanced CAE programs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ross, J.; Meyer, J.

1996-09-01

Due to the increased requirements for chain drive systems of 4-stroke internal combustion engines CAE-tools are necessary to design the optimum dynamic system. In comparison to models used din the past the advantage of the new model CDD (Chain Drive Dynamics) is the capability of simulating the trajectory of each chain link around the drive system. Each chain link is represented by a mass with two degrees of freedom and is coupled to the next by a spring-damper element. The drive sprocket can be moved with a constant or non-constant speed. As in reality the other sprockets are driven bymore » the running chain and can be excited by torques. Due to these unique model features it is possible to calculate all vibration types of the chain, polygon effects and radial or angular vibrations of the sprockets very accurately. The model includes the detailed simulation of a mechanical or a hydraulic tensioner as well. The method is ready to be coupled to other detailed calculation models (e.g. valve train systems, crankshaft, etc.). The high efficiency of the tool predicting the dynamic and acoustic behavior of a chain drive system will be demonstrated in comparison to measurements.« less

Durability Characteristics Analysis of Plastic Worm Wheel with Glass Fiber Reinforced Polyamide.

PubMed

Kim, Gun-Hee; Lee, Jeong-Won; Seo, Tae-Il

2013-05-10

Plastic worm wheel is widely used in the vehicle manufacturing field because it is favorable for weight lightening, vibration and noise reduction, as well as corrosion resistance. However, it is very difficult for general plastics to secure the mechanical properties that are required for vehicle gears. If the plastic resin is reinforced by glass fiber in the fabrication process of plastic worm wheel, it is possible to achieve the mechanical properties of metallic material levels. In this study, the mechanical characteristic analysis of the glass-reinforced plastic worm wheel, according to the contents of glass fiber, is performed by analytic and experimental methods. In the case of the glass fiber-reinforced resin, the orientation and contents of glass fibers can influence the mechanical properties. For the characteristic prediction of plastic worm wheel, computer-aided engineering (CAE) analysis processes such as structural and injection molding analysis were executed with the polyamide resin reinforcement glass fiber (25 wt %, 50 wt %). The injection mold for fabricating the prototype plastic worm wheel was designed and made to reflect the CAE analysis results. Finally, the durability of prototype plastic worm wheel fabricated by the injection molding process was evaluated by the experimental method and the characteristics according to the glass fiber contents.

Durability Characteristics Analysis of Plastic Worm Wheel with Glass Fiber Reinforced Polyamide

PubMed Central

Kim, Gun-Hee; Lee, Jeong-Won; Seo, Tae-Il

2013-01-01

Plastic worm wheel is widely used in the vehicle manufacturing field because it is favorable for weight lightening, vibration and noise reduction, as well as corrosion resistance. However, it is very difficult for general plastics to secure the mechanical properties that are required for vehicle gears. If the plastic resin is reinforced by glass fiber in the fabrication process of plastic worm wheel, it is possible to achieve the mechanical properties of metallic material levels. In this study, the mechanical characteristic analysis of the glass-reinforced plastic worm wheel, according to the contents of glass fiber, is performed by analytic and experimental methods. In the case of the glass fiber-reinforced resin, the orientation and contents of glass fibers can influence the mechanical properties. For the characteristic prediction of plastic worm wheel, computer-aided engineering (CAE) analysis processes such as structural and injection molding analysis were executed with the polyamide resin reinforcement glass fiber (25 wt %, 50 wt %). The injection mold for fabricating the prototype plastic worm wheel was designed and made to reflect the CAE analysis results. Finally, the durability of prototype plastic worm wheel fabricated by the injection molding process was evaluated by the experimental method and the characteristics according to the glass fiber contents. PMID:28809248

Proceedings of the Seventeenth Annual Software Engineering Workshop

NASA Technical Reports Server (NTRS)

1992-01-01

Proceedings of the Seventeenth Annual Software Engineering Workshop are presented. The software Engineering Laboratory (SEL) is an organization sponsored by NASA/Goddard Space Flight Center and created to investigate the effectiveness of software engineering technologies when applied to the development of applications software. Topics covered include: the Software Engineering Laboratory; process measurement; software reuse; software quality; lessons learned; and is Ada dying.

Software Past, Present, and Future: Views from Government, Industry and Academia

NASA Technical Reports Server (NTRS)

Holcomb, Lee; Page, Jerry; Evangelist, Michael

2000-01-01

Views from the NASA CIO NASA Software Engineering Workshop on software development from the past, present, and future are presented. The topics include: 1) Software Past; 2) Software Present; 3) NASA's Largest Software Challenges; 4) 8330 Software Projects in Industry Standish Groups 1994 Report; 5) Software Future; 6) Capability Maturity Model (CMM): Software Engineering Institute (SEI) levels; 7) System Engineering Quality Also Part of the Problem; 8) University Environment Trends Will Increase the Problem in Software Engineering; and 9) NASA Software Engineering Goals.

Method for automated building of spindle thermal model with use of CAE system

NASA Astrophysics Data System (ADS)

Kamenev, S. V.

2018-03-01

The spindle is one of the most important units of the metal-cutting machine tool. Its performance is critical to minimize the machining error, especially the thermal error. Various methods are applied to improve the thermal behaviour of spindle units. One of the most important methods is mathematical modelling based on the finite element analysis. The most common approach for its realization is the use of CAE systems. This approach, however, is not capable to address the number of important effects that need to be taken into consideration for proper simulation. In the present article, the authors propose the solution to overcome these disadvantages using automated thermal model building for the spindle unit utilizing the CAE system ANSYS.

Software engineering as an engineering discipline

NASA Technical Reports Server (NTRS)

Gibbs, Norman

1988-01-01

The goals of the Software Engineering Institute's Education Program are as follows: to increase the number of highly qualified software engineers--new software engineers and existing practitioners; and to be the leading center of expertise for software engineering education and training. A discussion of these goals is presented in vugraph form.

Software engineering as an engineering discipline

NASA Technical Reports Server (NTRS)

Berard, Edward V.

1988-01-01

The following topics are discussed in the context of software engineering: early use of the term; the 1968 NATO conference; Barry Boehm's definition; four requirements fo software engineering; and additional criteria for software engineering. Additionally, the four major requirements for software engineering--computer science, mathematics, engineering disciplines, and excellent communication skills--are discussed. The presentation is given in vugraph form.

Analysis of Parallelogram Mechanism used to Preserve Remote Center of Motion for Surgical Telemanipulator

NASA Astrophysics Data System (ADS)

Trochimczuk, R.

2017-02-01

This paper presents an analysis of a parallelogram mechanism commonly used to provide a kinematic remote center of motion in surgical telemanipulators. Selected types of parallel manipulator designs, encountered in commercial and laboratory-made designs described in the medical robotics literature, will serve as the research material. Among other things, computer simulations in the ANSYS 13.0 CAD/CAE software environment, employing the finite element method, will be used. The kinematics of the solution of manipulator with the parallelogram mechanism will be determined in order to provide a more complete description. These results will form the basis for the decision regarding the possibility of applying a parallelogram mechanism in an original prototype of a telemanipulator arm.

Preoperative and intraoperative predictors of cardiac adverse events after general, vascular, and urological surgery.

PubMed

Kheterpal, Sachin; O'Reilly, Michael; Englesbe, Michael J; Rosenberg, Andrew L; Shanks, Amy M; Zhang, Lingling; Rothman, Edward D; Campbell, Darrell A; Tremper, Kevin K

2009-01-01

The authors sought to determine the incidence and risk factors for perioperative cardiac adverse events (CAEs) after noncardiac surgery using detailed preoperative and intraoperative hemodynamic data. The authors conducted a prospective observational study at a single university hospital from 2002 to 2006. All American College of Surgeons-National Surgical Quality Improvement Program patients undergoing general, vascular, and urological surgery were included. The CAE outcome definition included cardiac arrest, non-ST elevation myocardial infarction, Q-wave myocardial infarction, and new clinically significant cardiac dysrhythmia within the first 30 postoperative days. Four years of data demonstrated that of 7,740 noncardiac operations, 83 patients (1.1%) experienced a CAE within 30 days. Nine independent predictors were identified (P < or = 0.05): age > or = 68, body mass index > or = 30, emergent surgery, previous coronary intervention or cardiac surgery, active congestive heart failure, cerebrovascular disease, hypertension, operative duration > or = 3.8 h, and the administration of 1 or more units of packed red blood cells intraoperatively. The c-statistic of this model was 0.81 +/- 0.02. Univariate analysis demonstrated that high-risk patients experiencing a CAE were more likely to experience an episode of mean arterial pressure < 50 mmHg (6% vs. 24%, P = 0.02), experience an episode of 40% decrease in mean arterial pressure (26% vs. 53%, P = 0.01), and an episode of heart rate > 100 (22% vs. 34%, P = 0.05). In comparison with current risk stratification indices, the inclusion of intraoperative elements improves the ability to predict a perioperative CAE after noncardiac surgery.

Annotated bibliography of Software Engineering Laboratory literature

NASA Technical Reports Server (NTRS)

Morusiewicz, Linda; Valett, Jon D.

1991-01-01

An annotated bibliography of technical papers, documents, and memorandums produced by or related to the Software Engineering Laboratory is given. More than 100 publications are summarized. These publications cover many areas of software engineering and range from research reports to software documentation. All materials have been grouped into eight general subject areas for easy reference: The Software Engineering Laboratory; The Software Engineering Laboratory: Software Development Documents; Software Tools; Software Models; Software Measurement; Technology Evaluations; Ada Technology; and Data Collection. Subject and author indexes further classify these documents by specific topic and individual author.

A Personal Memoir of Policy Failure: The Failed Merger of ANU and the Canberra CAE

ERIC Educational Resources Information Center

Scott, Roger

2004-01-01

The more immediate context of the events the author describes in this article is needed in order to identify the policy framework within which the Australian National University (ANU)-Canberra CAE (CCAE) merger was placed as a component of a wider public policy initiative undertaken by John Dawkins. There were four major components in that wider…

CAES 2014 Chemical Analyses of Thermal Wells and Springs in Southeastern Idaho

DOE Data Explorer

Baum, Jeffrey

2014-03-10

This dataset contains chemical analyses for thermal wells and springs in Southeastern Idaho. Data includes all major cations, major anions, pH, collection temperature, and some trace metals, These samples were collected in 2014 by the Center for Advanced Energy Studies (CAES), and are part of a continuous effort to analyze the geothermal potential of Southeastern Idaho.

Enduring Inequities, Imagined Futures--Circulating Policy Discourses and Dilemmas in the Anthropology of Education

ERIC Educational Resources Information Center

McCarty, Teresa L.

2012-01-01

This article is a slightly revised version of the CAE Presidential Address delivered at the Annual Meeting of the American Anthropological Association in New Orleans, LA on November 20, 2010. The address inaugurated a CAE program change in which a full evening session was devoted to the talk, including commentaries by Hugh Mehan and Sofia…

Compressional Alfvén eigenmodes in rotating spherical tokamak plasmas

DOE PAGES

Smith, H. M.; Fredrickson, E. D.

2017-02-07

Spherical tokamaks often have a considerable toroidal plasma rotation of several tens of kHz. Compressional Alfvén eigenmodes in such devices therefore experience a frequency shift, which if the plasma were rotating as a rigid body, would be a simple Doppler shift. However, since the rotation frequency depends on minor radius, the eigenmodes are affected in a more complicated way. The eigenmode solver CAE3B (Smith et al 2009 Plasma Phys. Control. Fusion 51 075001) has been extended to account for toroidal plasma rotation. The results show that the eigenfrequency shift due to rotation can be approximated by a rigid body rotationmore » with a frequency computed from a spatial average of the real rotation profile weighted with the eigenmode amplitude. To investigate the effect of extending the computational domain to the vessel wall, a simplified eigenmode equation, yet retaining plasma rotation, is solved by a modified version of the CAE code used in Fredrickson et al (2013 Phys. Plasmas 20 042112). Lastly, both solving the full eigenmode equation, as in the CAE3B code, and placing the boundary at the vessel wall, as in the CAE code, significantly influences the calculated eigenfrequencies.« less

Compressional Alfven Eigenmode Similarity Study

NASA Astrophysics Data System (ADS)

Heidbrink, W. W.; Fredrickson, E. D.; Gorelenkov, N. N.; Rhodes, T. L.

2004-11-01

NSTX and DIII-D are nearly ideal for Alfven eigenmode (AE) similarity experiments, having similar neutral beams, fast-ion to Alfven speed v_f/v_A, fast-ion pressure, and shape of the plasma, but with a factor of 2 difference in the major radius. Toroidicity-induced AE with ˜100 kHz frequencies were compared in an earlier study [1]; this paper focuses on higher frequency AE with f ˜ 1 MHz. Compressional AE (CAE) on NSTX have a polarization, dependence on the fast-ion distribution function, frequency scaling, and low-frequency limit that are qualitatively consistent with CAE theory [2]. Global AE (GAE) are also observed. On DIII-D, coherent modes in this frequency range are observed during low-field (0.6 T) similarity experiments. Experiments will compare the CAE stability limits on DIII-D with the NSTX stability limits, with the aim of determining if CAE will be excited by alphas in a reactor. Predicted differences in the frequency splitting Δ f between excited modes will also be used. \\vspace0.25em [1] W.W. Heidbrink, et al., Plasmas Phys. Control. Fusion 45, 983 (2003). [2] E.D. Fredrickson, et al., Princeton Plasma Physics Laboratory Report PPPL-3955 (2004).

Use of phase change materials during compressed air expansion for isothermal CAES plants

NASA Astrophysics Data System (ADS)

Castellani, B.; Presciutti, A.; Morini, E.; Filipponi, M.; Nicolini, A.; Rossi, F.

2017-11-01

Compressed air energy storage (CAES) plants are designed to store compressed air into a vessel or in an underground cavern and to expand it in an expansion turbine when energy demand is high. An innovative CAES configuration recently proposed is the isothermal process. Several methods to implement isothermal CAES configuration are under investigation. In this framework, the present paper deals with the experimental testing of phase change materials (PCM) during compressed air expansion phase. The experimental investigation was carried out by means of an apparatus constituted by a compression section, a steel pressure vessel, to which an expansion valve is connected. The initial internal absolute pressure was equal to 5 bar to avoid moisture condensation and the experimental tests were carried out with two paraffin-based PCM amounts (0.05 kg and 0.1 kg). Results show that the temperature change during air expansion decreases with increasing the PCM amount inside the vessel. With the use of PCM during expansions an increase of the expansion work occurs. The increase is included in the range from 9.3% to 18.2%. In every test there is an approach to the isothermal values, which represent the maximum theoretical value of the obtainable expansion work.

Software Engineering Laboratory Series: Proceedings of the Twentieth Annual Software Engineering Workshop

NASA Technical Reports Server (NTRS)

1995-01-01

The Software Engineering Laboratory (SEL) is an organization sponsored by NASA/GSFC and created to investigate the effectiveness of software engineering technologies when applied to the development of application software. The activities, findings, and recommendations of the SEL are recorded in the Software Engineering Laboratory Series, a continuing series of reports that includes this document.

Software Engineering Laboratory Series: Collected Software Engineering Papers. Volume 15

NASA Technical Reports Server (NTRS)

1997-01-01

The Software Engineering Laboratory (SEL) is an organization sponsored by NASA/GSFC and created to investigate the effectiveness of software engineering technologies when applied to the development of application software. The activities, findings, and recommendations of the SEL are recorded in the Software Engineering Laboratory Series, a continuing series of reports that includes this document.

Software Engineering Laboratory Series: Collected Software Engineering Papers. Volume 14

NASA Technical Reports Server (NTRS)

1996-01-01

The Software Engineering Laboratory (SEL) is an organization sponsored by NASA/GSFC and created to investigate the effectiveness of software engineering technologies when applied to the development of application software. The activities, findings, and recommendations of the SEL are recorded in the Software Engineering Laboratory Series, a continuing series of reports that includes this document.

Software Engineering Laboratory Series: Collected Software Engineering Papers. Volume 13

NASA Technical Reports Server (NTRS)

1995-01-01

The Software Engineering Laboratory (SEL) is an organization sponsored by NASA/GSFC and created to investigate the effectiveness of software engineering technologies when applied to the development of application software. The activities, findings, and recommendations of the SEL are recorded in the Software Engineering Laboratory Series, a continuing series of reports that includes this document.

Changing arctic ecosystems—What is causing the rapid increase of snow geese in northern Alaska?

USGS Publications Warehouse

Hupp, Jerry W.; Ward, David H.; Whalen, Mary E.; Pearce, John M.

2015-09-10

Through the Changing Arctic Ecosystems (CAE) initiative, the U.S. Geological Survey (USGS) informs key resource management decisions for Arctic Alaska by providing scientific information on current and future ecosystem response to a warming climate. The Arctic Coastal Plain (ACP) of northern Alaska is a key study area within the USGS CAE initiative. This region has experienced a warming trend over the past decades, leading to decreased sea ice, permafrost thaw, and an advancement of spring phenology. The number of birds on the ACP also is changing, marked by increased populations of the four species of geese that nest in the region. The Snow Goose (Chen caerulescens) is the most rapidly increasing of these species. USGS CAE research is quantifying these changes and their implications for management agencies.

Computer-Aided Software Engineering - An approach to real-time software development

NASA Technical Reports Server (NTRS)

Walker, Carrie K.; Turkovich, John J.

1989-01-01

A new software engineering discipline is Computer-Aided Software Engineering (CASE), a technology aimed at automating the software development process. This paper explores the development of CASE technology, particularly in the area of real-time/scientific/engineering software, and a history of CASE is given. The proposed software development environment for the Advanced Launch System (ALS CASE) is described as an example of an advanced software development system for real-time/scientific/engineering (RT/SE) software. The Automated Programming Subsystem of ALS CASE automatically generates executable code and corresponding documentation from a suitably formatted specification of the software requirements. Software requirements are interactively specified in the form of engineering block diagrams. Several demonstrations of the Automated Programming Subsystem are discussed.

Software engineering laboratory series: Annotated bibliography of software engineering laboratory literature

NASA Technical Reports Server (NTRS)

Morusiewicz, Linda; Valett, Jon

1992-01-01

This document is an annotated bibliography of technical papers, documents, and memorandums produced by or related to the Software Engineering Laboratory. More than 100 publications are summarized. These publications cover many areas of software engineering and range from research reports to software documentation. This document has been updated and reorganized substantially since the original version (SEL-82-006, November 1982). All materials have been grouped into eight general subject areas for easy reference: (1) the Software Engineering Laboratory; (2) the Software Engineering Laboratory: Software Development Documents; (3) Software Tools; (4) Software Models; (5) Software Measurement; (6) Technology Evaluations; (7) Ada Technology; and (8) Data Collection. This document contains an index of these publications classified by individual author.

Software Engineering Laboratory Series: Proceedings of the Twenty-First Annual Software Engineering Workshop

NASA Technical Reports Server (NTRS)

1996-01-01

The Software Engineering Laboratory (SEL) is an organization sponsored by NASA/GSFC and created to investigate the effectiveness of software engineering technologies when applied to the development of application software. The activities, findings, and recommendations of the SEL are recorded in the Software Engineering Laboratory Series, a continuing series of reports that includes this document.

Software Engineering Laboratory Series: Proceedings of the Twenty-Second Annual Software Engineering Workshop

NASA Technical Reports Server (NTRS)

1997-01-01

The Software Engineering Laboratory (SEL) is an organization sponsored by NASA/GSFC and created to investigate the effectiveness of software engineering technologies when applied to the development of application software. The activities, findings, and recommendations of the SEL are recorded in the Software Engineering Laboratory Series, a continuing series of reports that includes this document.

Software engineering and the role of Ada: Executive seminar

NASA Technical Reports Server (NTRS)

Freedman, Glenn B.

1987-01-01

The objective was to introduce the basic terminology and concepts of software engineering and Ada. The life cycle model is reviewed. The application of the goals and principles of software engineering is applied. An introductory understanding of the features of the Ada language is gained. Topics addressed include: the software crises; the mandate of the Space Station Program; software life cycle model; software engineering; and Ada under the software engineering umbrella.

Electric power generating plant having direct-coupled steam and compressed-air cycles

DOEpatents

Drost, M.K.

1981-01-07

An electric power generating plant is provided with a Compressed Air Energy Storage (CAES) system which is directly coupled to the steam cycle of the generating plant. The CAES system is charged by the steam boiler during off peak hours, and drives a separate generator during peak load hours. The steam boiler load is thereby levelized throughout an operating day.

Electric power generating plant having direct coupled steam and compressed air cycles

DOEpatents

Drost, Monte K.

1982-01-01

An electric power generating plant is provided with a Compressed Air Energy Storage (CAES) system which is directly coupled to the steam cycle of the generating plant. The CAES system is charged by the steam boiler during off peak hours, and drives a separate generator during peak load hours. The steam boiler load is thereby levelized throughout an operating day.

The Relationship between Vitamin D and Coronary Artery Ectasia in Subjects with a Normal C-Reactive Protein Level

PubMed Central

Cagirci, Goksel; Yuksel, Isa Oner; Bayar, Nermin; Koklu, Erkan; Guven, Ramazan; Arslan, Sakir

2017-01-01

Background and Objectives Vitamin D is generally known to be closely related to inflammation. The effects of vitamin D on coronary artery disease (CAD) are not fully explained. Nowadays, coronary artery ectasia (CAE) cases are common and are regarded as being a kind of CAD. We aimed to investigate, in a case-control study, the relationship between vitamin D and CAE without an associated inflammatory process. Subjects and Methods This study population included 201 patients (CAE group, 121 males; mean age, 61.2±6.4 years) with isolated CAE; and 197 healthy individuals (control group, 119 males; mean age, 62.4±5.8 years), comprising the control group, who had normal coronary arteries. These participants concurrently underwent routine biochemical tests, tests for inflammatory markers, and tests for 25-OH vitamin D in whole-blood draws. These parameters were compared. Results There are no statistical significance differences among the groups for basic clinical characteristics (p>0.05). Inflammatory markers were recorded and compared to exclude any inflammatory process. All of them were similar, and no statistical significance difference was found. The average parathyroid hormone (PTH) level of patients was higher than the average PTH level in controls (41.8±15.1 pg/mL vs. 19.1±5.81 pg/mL; p<0.001). Also, the average 25-OH vitamin D level of patients was lower than the average 25-OH vitamin D level of controls (14.5±6.3 ng/mL vs. 24.6±9.3 ng/mL; p<0.001). In receiver operating characteristic curve analysis, the observed cut-off value for vitamin D between the control group and patients was 10.8 and 85.6% sensitivity and 75.2% specificity (area under the curve: 0.854, 95% confidence interval: 0.678-0.863). Conclusion We found that there is an association between vitamin D and CAE in patients who had no inflammatory processes. Our study may provide evidence for the role of vitamin D as a non-inflammatory factor in the pathophysiology of CAE. PMID:28382079

Sensor data validation and reconstruction. Phase 1: System architecture study

NASA Technical Reports Server (NTRS)

1991-01-01

The sensor validation and data reconstruction task reviewed relevant literature and selected applicable validation and reconstruction techniques for further study; analyzed the selected techniques and emphasized those which could be used for both validation and reconstruction; analyzed Space Shuttle Main Engine (SSME) hot fire test data to determine statistical and physical relationships between various parameters; developed statistical and empirical correlations between parameters to perform validation and reconstruction tasks, using a computer aided engineering (CAE) package; and conceptually designed an expert system based knowledge fusion tool, which allows the user to relate diverse types of information when validating sensor data. The host hardware for the system is intended to be a Sun SPARCstation, but could be any RISC workstation with a UNIX operating system and a windowing/graphics system such as Motif or Dataviews. The information fusion tool is intended to be developed using the NEXPERT Object expert system shell, and the C programming language.

CAD Services: an Industry Standard Interface for Mechanical CAD Interoperability

NASA Technical Reports Server (NTRS)

Claus, Russell; Weitzer, Ilan

2002-01-01

Most organizations seek to design and develop new products in increasingly shorter time periods. At the same time, increased performance demands require a team-based multidisciplinary design process that may span several organizations. One approach to meet these demands is to use 'Geometry Centric' design. In this approach, design engineers team their efforts through one united representation of the design that is usually captured in a CAD system. Standards-based interfaces are critical to provide uniform, simple, distributed services that enable the 'Geometry Centric' design approach. This paper describes an industry-wide effort, under the Object Management Group's (OMG) Manufacturing Domain Task Force, to define interfaces that enable the interoperability of CAD, Computer Aided Manufacturing (CAM), and Computer Aided Engineering (CAE) tools. This critical link to enable 'Geometry Centric' design is called: Cad Services V1.0. This paper discusses the features of this standard and proposed application.

Annotated bibliography of software engineering laboratory literature

NASA Technical Reports Server (NTRS)

Groves, Paula; Valett, Jon

1990-01-01

An annotated bibliography of technical papers, documents, and memorandums produced by or related to the Software Engineering Laboratory is given. More than 100 publications are summarized. These publications cover many areas of software engineering and range from research reports to software documentation. This document has been updated and reorganized substantially since the original version (SEL-82-006, November 1982). All materials have been grouped into eight general subject areas for easy reference: the Software Engineering Laboratory; the Software Engineering Laboratory-software development documents; software tools; software models; software measurement; technology evaluations; Ada technology; and data collection. Subject and author indexes further classify these documents by specific topic and individual author.

Annotated bibliography of Software Engineering Laboratory literature

NASA Technical Reports Server (NTRS)

Morusiewicz, Linda; Valett, Jon

1993-01-01

This document is an annotated bibliography of technical papers, documents, and memorandums produced by or related to the Software Engineering Laboratory. Nearly 200 publications are summarized. These publications cover many areas of software engineering and range from research reports to software documentation. This document has been updated and reorganized substantially since the original version (SEL-82-006, November 1982). All materials have been grouped into eight general subject areas for easy reference: the Software Engineering Laboratory; the Software Engineering Laboratory: software development documents; software tools; software models; software measurement; technology evaluations; Ada technology; and data collection. This document contains an index of these publications classified by individual author.

A prospective trial of customized adherence enhancement plus long-acting injectable antipsychotic medication in homeless or recently homeless individuals with schizophrenia or schizoaffective disorder

PubMed Central

Sajatovic, Martha; Levin, Jennifer; Ramirez, Luis F.; Hahn, David Y.; Tatsuoka, Curtis; Bialko, Christopher S.; Cassidy, Kristin A.; Fuentes-Casiano, Edna; Williams, Tiffany D.

2014-01-01

Background Treatment non-adherence in people with schizophrenia is associated with relapse and homelessness. Building upon the usefulness of long-acting medication, and our work in psychosocial interventions to enhance adherence, we conducted a prospective uncontrolled trial of customized adherence enhancement (CAE) plus long-acting injectable antipsychotic (LAI) using haloperidol decanoate in 30 homeless or recently homeless individuals with schizophrenia and schizoaffective disorder. Methods Participants received monthly CAE and LAI (CAE-L) for 6 months. Primary outcomes were adherence as measured by the Tablets Routine Questionnaire (TRQ) and housing status. Secondary outcomes included psychiatric symptoms, functioning, side effects, and hospitalizations. Results Mean age of participants was 41.8 years (SD 8.6), mainly minorities (90% African-American) and mainly single/never married (70%). Most (97%) had past or current substance abuse, and had been incarcerated (97%). Ten individuals (33%) terminated the study prematurely. CAE-L was associated with good adherence to LAI (76% at 6 months) and dramatic improvement in oral medication adherence, which changed from missing 46% of medication at study enrollment to missing only 10% at study end (p = 0.03). There were significant improvements in psychiatric symptoms (p<.001) and functioning (p<.001). Akathisia was a major side effect with LAI. Conclusion While interpretation of findings must be tempered by the methodological limitations, CAE-L appears to be associated with improved adherence, symptoms, and functioning in homeless or recently homeless individuals with schizophrenia or schizoaffective disorder. Additional research is needed on effective and practical approaches to improving health outcomes for homeless people with serious mental illness. PMID:24434094

Routine Leak Testing in Colorectal Surgery in the Surgical Care and Outcomes Assessment Program

PubMed Central

Kwon, Steve; Morris, Arden; Billingham, Richard; Frankhouse, Joseph; Horvath, Karen; Johnson, Morrie; McNevin, Shane; Simons, Anthony; Symons, Rebecca; Steele, Scott; Thirlby, Richard; Whiteford, Mark; Flum, David R.

2014-01-01

Objective To evaluate the effect of routine anastomotic leak testing (performed to screen for leaks) vs selective testing (performed to evaluate for a suspected leak in a higher-risk or technically difficult anastomosis) on outcomes in colorectal surgery because the value of provocative testing of colorectal anastomoses as a quality improvement metric has yet to be determined. Design Observational, prospectively designed cohort study. Setting Data from Washington state’s Surgical Care and Outcomes Assessment Program (SCOAP). Patients Patients undergoing elective left-sided colon or rectal resections at 40 SCOAP hospitals from October 1, 2005, to December 31, 2009. Interventions Use of leak testing, distinguishing procedures that were performed at hospitals where leak testing was selective (<90% use) or routine (≥90% use) in a given calendar quarter. Main Outcome Measure Adjusted odds ratio of a composite adverse event (CAE) (unplanned postoperative intervention and/or in-hospital death) at routine testing hospitals. Results Among 3449 patients (mean [SD] age, 58.8[14.8] years; 55.0% women), the CAE rate was 5.5%. Provocative leak testing increased (from 56% in the starting quarter to 76% in quarter 16) and overall rates of CAE decreased (from 7.0% in the starting quarter to 4.6% in quarter 16; both P ≤ .01) over time. Among patients at hospitals that performed routine leak testing, we found a reduction of more than 75% in the adjusted risk of CAEs (odds ratio, 0.23; 95% CI, 0.05–0.99). Conclusion Routine leak testing of left-sided colorectal anastomoses appears to be associated with a reduced rate of CAEs within the SCOAP network and meets many of the criteria of a worthwhile quality improvement metric. PMID:22508778

Prolonged survival of reconstituted skin grafts without immunosuppression.

PubMed

Sasamoto, Y; Alexander, J W; Babcock, G F

1990-01-01

Reconstituted skin composed of a cultured allogeneic epithelial sheet (CAES) and a cultured allogeneic dermis (CAD) was evaluated in a rat model to determine whether it could survive for a prolonged period without immunosuppression. Additionally, free CAD grafts were evaluated for their suitability as dermal substitutes. Male Buffalo rats were used as donors and male Lewis rats as recipients. Split-thickness skin obtained from Buffalo rats was separated into epidermis and dermis by means of Dispase II enzyme. The epidermal layers were minced and trypsinized. Then dispersed single keratinocytes were inoculated onto a irradiated 3T3 cell feeder layer. After a suitable period, a confluent cultured keratinocyte layer was detached and provided CAES grafts. Cultured allogeneic dermis grafts were prepared from cultures of the dermal component. Cultured allogeneic dermis grafts, covered by split thickness isografts (STIG) or local skin flaps, became revascularized at a rate of 94.6% and 90.9%, respectively, 7 days after grafting. However, only 25% of CAD grafts covered by synthetic materials became vascularized. Four types of wound coverage were compared including: (1) CAES grafts, (2) CAES over CAD grafts, (3) split-thickness isografts, and (4) STIG over CAD grafts. In groups 2 and 4, CAD grafts were applied 7 days before CAES grafts or STIG. Grafts of groups 1 and 2 were successful in only 36.7% and 31.1% of the animals and resulted in a high rate of wound contracture--72.4%, 66.7%, respectively. On the other hand, in groups 3 and 4, higher average rates of revascularization (92.0% and 88.3%) and lower rates of wound contracture (25.4% and 24.2%) were obtained.(ABSTRACT TRUNCATED AT 250 WORDS)

Prognostic Role of Hypertensive Response to Exercise in Patients With Repaired Coarctation of Aorta.

PubMed

Yogeswaran, Vidhushei; Connolly, Heidi M; Al-Otaibi, Mohamad; Ammash, Naser M; Warnes, Carole A; Said, Sameh M; Egbe, Alexander C

2018-05-01

This study aimed to determine the prevalence of hypertensive response to exercise (HRE) and its association with cardiovascular adverse events (CAEs) in patients with repaired coarctation of aorta (rCOA). We retrospectively reviewed records of adult patients with rCOA who had cardiopulmonary exercise tests (CPETs) and follow-up from 1994 to 2014 at Mayo Clinic. Patients with residual COA, defined as aortic isthmus peak velocity >2.5 m/s, were excluded. HRE was defined as peak systolic blood pressure >200 mm Hg; CAEs were defined as cardiovascular death, stroke, acute coronary syndrome, heart failure hospitalization, and left ventricular ejection fraction (LVEF) < 35%. One hundred thirty-eight patients (82 men [59%]) underwent 213 CPETs, with follow-up of 85 ± 13 months. Age at initial COA repair was 9 ± 3 years; age at initial CPET was 40 ± 13 years. HRE occurred in 26 (19%) patients, and 24 (92%) of the patients with HRE had normal resting blood pressure. There were no differences in age, blood pressure at rest, and CPET findings between patients with HRE and those with normotensive response to exercise. There were 28 CAEs in 24 patients (17%), and HRE was an independent risk factor for CAE (hazard ratio [HR], 1.46 [1.13-2.52]; P = 0.04). HRE can occur even in the setting of normal blood pressure at rest, and it is a risk factor for CAE. We speculate that patients with HRE represent a high-risk group of patients who, presumably, have occult, advanced vascular dysfunction. CPET can identify these patients. The benefit of intensive antihypertension therapy needs to be confirmed. Copyright © 2018 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

Routine leak testing in colorectal surgery in the Surgical Care and Outcomes Assessment Program.

PubMed

Kwon, Steve; Morris, Arden; Billingham, Richard; Frankhouse, Joseph; Horvath, Karen; Johnson, Morrie; McNevin, Shane; Simons, Anthony; Symons, Rebecca; Steele, Scott; Thirlby, Richard; Whiteford, Mark; Flum, David R

2012-04-01

To evaluate the effect of routine anastomotic leak testing (performed to screen for leaks) vs selective testing (performed to evaluate for a suspected leak in a higher-risk or technically difficult anastomosis) on outcomes in colorectal surgery because the value of provocative testing of colorectal anastomoses as a quality improvement metric has yet to be determined. Observational, prospectively designed cohort study. Data from Washington state's Surgical Care and Outcomes Assessment Program (SCOAP). Patients undergoing elective left-sided colon or rectal resections at 40 SCOAP hospitals from October 1, 2005, to December 31, 2009. Use of leak testing, distinguishing procedures that were performed at hospitals where leak testing was selective (<90% use) or routine (≥ 90% use) in a given calendar quarter. Adjusted odds ratio of a composite adverse event (CAE) (unplanned postoperative intervention and/or in-hospital death) at routine testing hospitals. Among 3449 patients (mean [SD] age, 58.8 [14.8] years; 55.0% women), the CAE rate was 5.5%. Provocative leak testing increased (from 56% in the starting quarter to 76% in quarter 16) and overall rates of CAE decreased (from 7.0% in the starting quarter to 4.6% in quarter 16; both P ≤ .01) over time. Among patients at hospitals that performed routine leak testing, we found a reduction of more than 75% in the adjusted risk of CAEs (odds ratio, 0.23; 95% CI, 0.05-0.99). Routine leak testing of left-sided colorectal anastomoses appears to be associated with a reduced rate of CAEs within the SCOAP network and meets many of the criteria of a worthwhile quality improvement metric.

Software Development for EECU Platform of Turbofan Engine

NASA Astrophysics Data System (ADS)

Kim, Bo Gyoung; Kwak, Dohyup; Kim, Byunghyun; Choi, Hee ju; Kong, Changduk

2017-04-01

The turbofan engine operation consists of a number of hardware and software. The engine is controlled by Electronic Engine Control Unit (EECU). In order to control the engine, EECU communicates with an aircraft system, Actuator Drive Unit (ADU), Engine Power Unit (EPU) and sensors on the engine. This paper tried to investigate the process form starting to taking-off and aims to design the EECU software mode and defined communication data format. The software is implemented according to the designed software mode.

Software engineering methodologies and tools

NASA Technical Reports Server (NTRS)

Wilcox, Lawrence M.

1993-01-01

Over the years many engineering disciplines have developed, including chemical, electronic, etc. Common to all engineering disciplines is the use of rigor, models, metrics, and predefined methodologies. Recently, a new engineering discipline has appeared on the scene, called software engineering. For over thirty years computer software has been developed and the track record has not been good. Software development projects often miss schedules, are over budget, do not give the user what is wanted, and produce defects. One estimate is there are one to three defects per 1000 lines of deployed code. More and more systems are requiring larger and more complex software for support. As this requirement grows, the software development problems grow exponentially. It is believed that software quality can be improved by applying engineering principles. Another compelling reason to bring the engineering disciplines to software development is productivity. It has been estimated that productivity of producing software has only increased one to two percent a year in the last thirty years. Ironically, the computer and its software have contributed significantly to the industry-wide productivity, but computer professionals have done a poor job of using the computer to do their job. Engineering disciplines and methodologies are now emerging supported by software tools that address the problems of software development. This paper addresses some of the current software engineering methodologies as a backdrop for the general evaluation of computer assisted software engineering (CASE) tools from actual installation of and experimentation with some specific tools.

An overview of the Small Engine Component Technology (SECT) studies

NASA Technical Reports Server (NTRS)

Vanco, M. R.; Wintucky, W. T.; Niedzwiecki, R. W.

1986-01-01

The objectives of the joint NASA/Army SECT Studies were to identify high payoff technologies for year 2000 small gas turbine engine applications and to provide a technology plan for guiding future research and technology efforts applicable to rotorcraft, commuter and general aviation aircraft and cruise missiles. Competitive contracts were awarded to Allison, AVCO Lycoming, Garrett, Teledyne CAE and Williams International. This paper presents an overview of the contractors' study efforts for the commuter, rotorcraft, cruise missile, and auxiliary power (APU) applications with engines in the 250 to 1,000 horsepower size range. Reference aircraft, missions and engines were selected. Advanced engine configurations and cycles with projected year 2000 component technologies were evaluated and compared with a reference engine selected by the contractor. For typical commuter and rotorcraft applications, fuel savings of 22 percent to 42 percent can be attained. For $1/gallon and $2/gallon fuel, reductions in direct operating cost range from 6 percent to 16 percent and from 11 percent to 17 percent respectively. For subsonic strategic cruise missile applications, fuel savings of 38 percent to 54 percent can be achieved which allows 35 percent to 60 percent increase in mission range and life cycle cost reductions of 40 percent to 56 percent. High payoff technologies have been identified for all applications.

Followup Audit: Enterprise Blood Management System Not Ready for Full Deployment

DTIC Science & Technology

2014-10-23

Executive ( CAE ) for DHA considered these two systems as a single Defense acquisition category III automated information system.2 According to the...the improved integration of blood products inventory management and shipment availability. The CAE for DHA is the milestone decision authority for...to officials, the capability is a web-based IT product used to track blood products in theater. Specifically, theater-based medical treatment

The Comparison of Inductive Reasoning under Risk Conditions between Chinese and Japanese Based on Computational Models: Toward the Application to CAE for Foreign Language

ERIC Educational Resources Information Center

Zhang, Yujie; Terai, Asuka; Nakagawa, Masanori

2013-01-01

Inductive reasoning under risk conditions is an important thinking process not only for sciences but also in our daily life. From this viewpoint, it is very useful for language learning to construct computational models of inductive reasoning which realize the CAE for foreign languages. This study proposes the comparison of inductive reasoning…

Oxidative DNA damage preventive activity and antioxidant potential of Stevia rebaudiana (Bertoni) Bertoni, a natural sweetener.

PubMed

Ghanta, Srijani; Banerjee, Anindita; Poddar, Avijit; Chattopadhyay, Sharmila

2007-12-26

At 0.1 mg/mL, the ethyl acetate extract (EAE) of the crude 85% methanolic extract (CAE) of Stevia rebaudiana leaves exhibited preventive activity against DNA strand scission by *OH generated in Fenton's reaction on pBluescript II SK (-) DNA. Its efficacy is better than that of quercetin. The radical scavenging capacity of CAE was evaluated by the DPPH test (IC50=47.66+/-1.04 microg/mL). EAE was derived from CAE scavenged DPPH (IC50=9.26+/-0.04 microg/mL), ABTS+ (IC50=3.04+/-0.22 microg/mL) and *OH (IC50=3.08+/-0.19 microg/mL). Additionally, inhibition of lipid peroxidation induced with 25 mM FeSO 4 on rat liver homogenate as a lipid source was noted with CAE (IC50=2.1+/-1.07 mg/mL). The total polyphenols and total flavonoids of EAE were 0.86 mg gallic acid equivalents/mg and 0.83 mg of quercetin equivalents/mg, respectively. Flavonoids, isolated from EAE, were characterized as quercetin-3-O-arabinoside, quercitrin, apigenin, apigenin-4-O-glucoside, luteolin, and kaempferol-3-O-rhamnoside by LC-MS and NMR analysis. These results indicate that Stevia rebaudiana may be useful as a potential source of natural antioxidants.

Beneficial Effects of the Genus Aloe on Wound Healing, Cell Proliferation, and Differentiation of Epidermal Keratinocytes

PubMed Central

Uda, Junki; Kubo, Hirokazu; Nakajima, Yuka; Goto, Arisa; Akaki, Junji; Yoshida, Ikuyo; Matsuoka, Nobuya; Hayakawa, Takao

2016-01-01

Aloe has been used as a folk medicine because it has several important therapeutic properties. These include wound and burn healing, and Aloe is now used in a variety of commercially available topical medications for wound healing and skin care. However, its effects on epidermal keratinocytes remain largely unclear. Our data indicated that both Aloe vera gel (AVG) and Cape aloe extract (CAE) significantly improved wound healing in human primary epidermal keratinocytes (HPEKs) and a human skin equivalent model. In addition, flow cytometry analysis revealed that cell surface expressions of β1-, α6-, β4-integrin, and E-cadherin increased in HPEKs treated with AVG and CAE. These increases may contribute to cell migration and wound healing. Treatment with Aloe also resulted in significant changes in cell-cycle progression and in increases in cell number. Aloe increased gene expression of differentiation markers in HPEKs, suggesting roles for AVG and CAE in the improvement of keratinocyte function. Furthermore, human skin epidermal equivalents developed from HPEKs with medium containing Aloe were thicker than control equivalents, indicating the effectiveness of Aloe on enhancing epidermal development. Based on these results, both AVG and CAE have benefits in wound healing and in treatment of rough skin. PMID:27736988

Annotated bibliography of software engineering laboratory literature

NASA Technical Reports Server (NTRS)

Kistler, David; Bristow, John; Smith, Don

1994-01-01

This document is an annotated bibliography of technical papers, documents, and memorandums produced by or related to the Software Engineering Laboratory. Nearly 200 publications are summarized. These publications cover many areas of software engineering and range from research reports to software documentation. This document has been updated and reorganized substantially since the original version (SEL-82-006, November 1982). All materials have been grouped into eight general subject areas for easy reference: (1) The Software Engineering Laboratory; (2) The Software Engineering Laboratory: Software Development Documents; (3) Software Tools; (4) Software Models; (5) Software Measurement; (6) Technology Evaluations; (7) Ada Technology; and (8) Data Collection. This document contains an index of these publications classified by individual author.

Software Engineering Improvement Activities/Plan

NASA Technical Reports Server (NTRS)

2003-01-01

bd Systems personnel accomplished the technical responsibilities for this reporting period, as planned. A close working relationship was maintained with personnel of the MSFC Avionics Department Software Group (ED14). Work accomplishments included development, evaluation, and enhancement of a software cost model, performing literature search and evaluation of software tools available for code analysis and requirements analysis, and participating in other relevant software engineering activities. Monthly reports were submitted. This support was provided to the Flight Software Group/ED 1 4 in accomplishing the software engineering improvement engineering activities of the Marshall Space Flight Center (MSFC) Software Engineering Improvement Plan.

Engineering bioinformatics: building reliability, performance and productivity into bioinformatics software.

PubMed

Lawlor, Brendan; Walsh, Paul

2015-01-01

There is a lack of software engineering skills in bioinformatic contexts. We discuss the consequences of this lack, examine existing explanations and remedies to the problem, point out their shortcomings, and propose alternatives. Previous analyses of the problem have tended to treat the use of software in scientific contexts as categorically different from the general application of software engineering in commercial settings. In contrast, we describe bioinformatic software engineering as a specialization of general software engineering, and examine how it should be practiced. Specifically, we highlight the difference between programming and software engineering, list elements of the latter and present the results of a survey of bioinformatic practitioners which quantifies the extent to which those elements are employed in bioinformatics. We propose that the ideal way to bring engineering values into research projects is to bring engineers themselves. We identify the role of Bioinformatic Engineer and describe how such a role would work within bioinformatic research teams. We conclude by recommending an educational emphasis on cross-training software engineers into life sciences, and propose research on Domain Specific Languages to facilitate collaboration between engineers and bioinformaticians.

Engineering bioinformatics: building reliability, performance and productivity into bioinformatics software

PubMed Central

Lawlor, Brendan; Walsh, Paul

2015-01-01

There is a lack of software engineering skills in bioinformatic contexts. We discuss the consequences of this lack, examine existing explanations and remedies to the problem, point out their shortcomings, and propose alternatives. Previous analyses of the problem have tended to treat the use of software in scientific contexts as categorically different from the general application of software engineering in commercial settings. In contrast, we describe bioinformatic software engineering as a specialization of general software engineering, and examine how it should be practiced. Specifically, we highlight the difference between programming and software engineering, list elements of the latter and present the results of a survey of bioinformatic practitioners which quantifies the extent to which those elements are employed in bioinformatics. We propose that the ideal way to bring engineering values into research projects is to bring engineers themselves. We identify the role of Bioinformatic Engineer and describe how such a role would work within bioinformatic research teams. We conclude by recommending an educational emphasis on cross-training software engineers into life sciences, and propose research on Domain Specific Languages to facilitate collaboration between engineers and bioinformaticians. PMID:25996054

Software Engineering for Human Spaceflight

NASA Technical Reports Server (NTRS)

Fredrickson, Steven E.

2014-01-01

The Spacecraft Software Engineering Branch of NASA Johnson Space Center (JSC) provides world-class products, leadership, and technical expertise in software engineering, processes, technology, and systems management for human spaceflight. The branch contributes to major NASA programs (e.g. ISS, MPCV/Orion) with in-house software development and prime contractor oversight, and maintains the JSC Engineering Directorate CMMI rating for flight software development. Software engineering teams work with hardware developers, mission planners, and system operators to integrate flight vehicles, habitats, robotics, and other spacecraft elements. They seek to infuse automation and autonomy into missions, and apply new technologies to flight processor and computational architectures. This presentation will provide an overview of key software-related projects, software methodologies and tools, and technology pursuits of interest to the JSC Spacecraft Software Engineering Branch.

Data encryption standard ASIC design and development report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robertson, Perry J.; Pierson, Lyndon George; Witzke, Edward L.

2003-10-01

This document describes the design, fabrication, and testing of the SNL Data Encryption Standard (DES) ASIC. This device was fabricated in Sandia's Microelectronics Development Laboratory using 0.6 {micro}m CMOS technology. The SNL DES ASIC was modeled using VHDL, then simulated, and synthesized using Synopsys, Inc. software and finally IC layout was performed using Compass Design Automation's CAE tools. IC testing was performed by Sandia's Microelectronic Validation Department using a HP 82000 computer aided test system. The device is a single integrated circuit, pipelined realization of DES encryption and decryption capable of throughputs greater than 6.5 Gb/s. Several enhancements accommodate ATMmore » or IP network operation and performance scaling. This design is the latest step in the evolution of DES modules.« less

Software engineering from a Langley perspective

NASA Technical Reports Server (NTRS)

Voigt, Susan

1994-01-01

A brief introduction to software engineering is presented. The talk is divided into four sections beginning with the question 'What is software engineering', followed by a brief history of the progression of software engineering at the Langley Research Center in the context of an expanding computing environment. Several basic concepts and terms are introduced, including software development life cycles and maturity levels. Finally, comments are offered on what software engineering means for the Langley Research Center and where to find more information on the subject.

The need for scientific software engineering in the pharmaceutical industry

NASA Astrophysics Data System (ADS)

Luty, Brock; Rose, Peter W.

2017-03-01

Scientific software engineering is a distinct discipline from both computational chemistry project support and research informatics. A scientific software engineer not only has a deep understanding of the science of drug discovery but also the desire, skills and time to apply good software engineering practices. A good team of scientific software engineers can create a software foundation that is maintainable, validated and robust. If done correctly, this foundation enable the organization to investigate new and novel computational ideas with a very high level of efficiency.

The need for scientific software engineering in the pharmaceutical industry.

PubMed

Luty, Brock; Rose, Peter W

2017-03-01

Scientific software engineering is a distinct discipline from both computational chemistry project support and research informatics. A scientific software engineer not only has a deep understanding of the science of drug discovery but also the desire, skills and time to apply good software engineering practices. A good team of scientific software engineers can create a software foundation that is maintainable, validated and robust. If done correctly, this foundation enable the organization to investigate new and novel computational ideas with a very high level of efficiency.

Experimentation in software engineering

NASA Technical Reports Server (NTRS)

Basili, V. R.; Selby, R. W.; Hutchens, D. H.

1986-01-01

Experimentation in software engineering supports the advancement of the field through an iterative learning process. In this paper, a framework for analyzing most of the experimental work performed in software engineering over the past several years is presented. A variety of experiments in the framework is described and their contribution to the software engineering discipline is discussed. Some useful recommendations for the application of the experimental process in software engineering are included.

SAGA: A project to automate the management of software production systems

NASA Technical Reports Server (NTRS)

Campbell, Roy H.; Beckman-Davies, C. S.; Benzinger, L.; Beshers, G.; Laliberte, D.; Render, H.; Sum, R.; Smith, W.; Terwilliger, R.

1986-01-01

Research into software development is required to reduce its production cost and to improve its quality. Modern software systems, such as the embedded software required for NASA's space station initiative, stretch current software engineering techniques. The requirements to build large, reliable, and maintainable software systems increases with time. Much theoretical and practical research is in progress to improve software engineering techniques. One such technique is to build a software system or environment which directly supports the software engineering process, i.e., the SAGA project, comprising the research necessary to design and build a software development which automates the software engineering process. Progress under SAGA is described.

Performance evaluation of NASA/KSC CAD/CAE graphics local area network

NASA Technical Reports Server (NTRS)

Zobrist, George

1988-01-01

This study had as an objective the performance evaluation of the existing CAD/CAE graphics network at NASA/KSC. This evaluation will also aid in projecting planned expansions, such as the Space Station project on the existing CAD/CAE network. The objectives were achieved by collecting packet traffic on the various integrated sub-networks. This included items, such as total number of packets on the various subnetworks, source/destination of packets, percent utilization of network capacity, peak traffic rates, and packet size distribution. The NASA/KSC LAN was stressed to determine the useable bandwidth of the Ethernet network and an average design station workload was used to project the increased traffic on the existing network and the planned T1 link. This performance evaluation of the network will aid the NASA/KSC network managers in planning for the integration of future workload requirements into the existing network.

Installation Restoration Program. Preliminary Assessment: 143rd Tactical Airlift Group, Rhode Island Air National Guard, Quonset State Airport, North Kingstown, Rhode Island

DTIC Science & Technology

1990-06-01

portions of the master plan and preliminary engineering for a new international airport for Lisbon, Portugal , estimated to cost $250 million. Self... sinES awtuc, SiC,9 @, Sta. 0.4.. Loc.’ el v t tim w . made weet of 66 water to. dril Sl thr0 g concrete.~ oa~~ 4.80 L0051 1.450, a. Di caes"J @tknwe...8217:par-i SI17. lilt)*~ fir, Sai~d. irav nir 1 ,l 111.-li 1s -w-i-l, a 6-Inch lent, Of coals ,- t. tint SANUI. li1tle Silt l(ll) GFIAPNhf SISCCULI/ O REMAR

Logic Design Pathology and Space Flight Electronics

NASA Technical Reports Server (NTRS)

Katz, Richard; Barto, Rod L.; Erickson, K.

1997-01-01

Logic design errors have been observed in space flight missions and the final stages of ground test. The technologies used by designers and their design/analysis methodologies will be analyzed. This will give insight to the root causes of the failures. These technologies include discrete integrated circuit based systems, systems based on field and mask programmable logic, and the use computer aided engineering (CAE) systems. State-of-the-art (SOTA) design tools and methodologies will be analyzed with respect to high-reliability spacecraft design and potential pitfalls are discussed. Case studies of faults from large expensive programs to "smaller, faster, cheaper" missions will be used to explore the fundamental reasons for logic design problems.

Software development environments: Status and trends

NASA Technical Reports Server (NTRS)

Duffel, Larry E.

1988-01-01

Currently software engineers are the essential integrating factors tying several components together. The components consist of process, methods, computers, tools, support environments, and software engineers. The engineers today empower the tools versus the tools empowering the engineers. Some of the issues in software engineering are quality, managing the software engineering process, and productivity. A strategy to accomplish this is to promote the evolution of software engineering from an ad hoc, labor intensive activity to a managed, technology supported discipline. This strategy may be implemented by putting the process under management control, adopting appropriate methods, inserting the technology that provides automated support for the process and methods, collecting automated tools into an integrated environment and educating the personnel.

Proceedings of Tenth Annual Software Engineering Workshop

NASA Technical Reports Server (NTRS)

1985-01-01

Papers are presented on the following topics: measurement of software technology, recent studies of the Software Engineering Lab, software management tools, expert systems, error seeding as a program validation technique, software quality assurance, software engineering environments (including knowledge-based environments), the Distributed Computing Design System, and various Ada experiments.

Annotated bibliography of software engineering laboratory literature

NASA Technical Reports Server (NTRS)

Buhler, Melanie; Valett, Jon

1989-01-01

An annotated bibliography is presented of technical papers, documents, and memorandums produced by or related to the Software Engineering Laboratory. The bibliography was updated and reorganized substantially since the original version (SEL-82-006, November 1982). All materials were grouped into eight general subject areas for easy reference: (1) The Software Engineering Laboratory; (2) The Software Engineering Laboratory: Software Development Documents; (3) Software Tools; (4) Software Models; (5) Software Measurement; (6) Technology Evaluations; (7) Ada Technology; and (8) Data Collection. Subject and author indexes further classify these documents by specific topic and individual author.

In the soft-to-hard technical spectrum: Where is software engineering?

NASA Technical Reports Server (NTRS)

Leibfried, Theodore F.; Macdonald, Robert B.

1992-01-01

In the computer journals and tabloids, there have been a plethora of articles written about the software engineering field. But while advocates of the need for an engineering approach to software development, it is impressive how many authors have treated the subject of software engineering without adequately addressing the fundamentals of what engineering as a discipline consists of. A discussion is presented of the various related facets of this issue in a logical framework to advance the thesis that the software development process is necessarily an engineering process. The purpose is to examine more of the details of the issue of whether or not the design and development of software for digital computer processing systems should be both viewed and treated as a legitimate field of professional engineering. Also, the type of academic and professional level education programs that would be required to support a software engineering discipline is examined.

Software Engineering Education Directory

DTIC Science & Technology

1990-04-01

and Engineering (CMSC 735) Codes: GPEV2 * Textiooks: IEEE Tutoria on Models and Metrics for Software Management and Engameeing by Basi, Victor R...Software Engineering (Comp 227) Codes: GPRY5 Textbooks: IEEE Tutoria on Software Design Techniques by Freeman, Peter and Wasserman, Anthony 1. Software

The research and practice of spacecraft software engineering

NASA Astrophysics Data System (ADS)

Chen, Chengxin; Wang, Jinghua; Xu, Xiaoguang

2017-06-01

In order to ensure the safety and reliability of spacecraft software products, it is necessary to execute engineering management. Firstly, the paper introduces the problems of unsystematic planning, uncertain classified management and uncontinuous improved mechanism in domestic and foreign spacecraft software engineering management. Then, it proposes a solution for software engineering management based on system-integrated ideology in the perspective of spacecraft system. Finally, a application result of spacecraft is given as an example. The research can provides a reference for executing spacecraft software engineering management and improving software product quality.

A CAD/CAE analysis of photographic and engineering data

NASA Technical Reports Server (NTRS)

Goza, S. Michael; Peterson, Wayne L.

1987-01-01

In the investigation of the STS 51L accident, NASA engineers were given the task of visual analysis of photographic data extracted from the tracking cameras located at the launch pad. An analysis of the rotations associated with the right Solid Rocket Booster (SRB) was also performed. The visual analysis involved pinpointing coordinates of specific areas on the photographs. The objective of the analysis on the right SRB was to duplicate the rotations provided by the SRB rate gyros and to determine the effects of the rotations on the launch configuration. To accomplish the objectives, computer aided design and engineering was employed. The solid modeler, GEOMOD, inside the Structural Dynamics Research Corp. I-DEAS package, proved invaluable. The problem areas that were encountered and the corresponding solutions that were obtained are discussed. A brief description detailing the construction of the computer generated solid model of the STS launch configuration is given. A discussion of the coordinate systems used in the analysis is provided for the purpose of positioning the model in coordinate space. The techniques and theory used in the model analysis are described.

Data systems and computer science: Software Engineering Program

NASA Technical Reports Server (NTRS)

Zygielbaum, Arthur I.

1991-01-01

An external review of the Integrated Technology Plan for the Civil Space Program is presented. This review is specifically concerned with the Software Engineering Program. The goals of the Software Engineering Program are as follows: (1) improve NASA's ability to manage development, operation, and maintenance of complex software systems; (2) decrease NASA's cost and risk in engineering complex software systems; and (3) provide technology to assure safety and reliability of software in mission critical applications.

Modeling software systems by domains

NASA Technical Reports Server (NTRS)

Dippolito, Richard; Lee, Kenneth

1992-01-01

The Software Architectures Engineering (SAE) Project at the Software Engineering Institute (SEI) has developed engineering modeling techniques that both reduce the complexity of software for domain-specific computer systems and result in systems that are easier to build and maintain. These techniques allow maximum freedom for system developers to apply their domain expertise to software. We have applied these techniques to several types of applications, including training simulators operating in real time, engineering simulators operating in non-real time, and real-time embedded computer systems. Our modeling techniques result in software that mirrors both the complexity of the application and the domain knowledge requirements. We submit that the proper measure of software complexity reflects neither the number of software component units nor the code count, but the locus of and amount of domain knowledge. As a result of using these techniques, domain knowledge is isolated by fields of engineering expertise and removed from the concern of the software engineer. In this paper, we will describe kinds of domain expertise, describe engineering by domains, and provide relevant examples of software developed for simulator applications using the techniques.

Development of an expert system for the simulation model for casting metal substructure of a metal-ceramic crown design.

PubMed

Matin, Ivan; Hadzistevic, Miodrag; Vukelic, Djordje; Potran, Michal; Brajlih, Tomaz

2017-07-01

Nowadays, the integrated CAD/CAE systems are favored solutions for the design of simulation models for casting metal substructures of metal-ceramic crowns. The worldwide authors have used different approaches to solve the problems using an expert system. Despite substantial research progress in the design of experts systems for the simulation model design and manufacturing have insufficiently considered the specifics of casting in dentistry, especially the need for further CAD, RE, CAE for the estimation of casting parameters and the control of the casting machine. The novel expert system performs the following: CAD modeling of the simulation model for casting, fast modeling of gate design, CAD eligibility and cast ability check of the model, estimation and running of the program code for the casting machine, as well as manufacturing time reduction of the metal substructure. The authors propose an integration method using common data model approach, blackboard architecture, rule-based reasoning and iterative redesign method. Arithmetic mean roughness values was determinated with constant Gauss low-pass filter (cut-off length of 2.5mm) according to ISO 4287 using Mahr MARSURF PS1. Dimensional deviation between the designed model and manufactured cast was determined using the coordinate measuring machine Zeiss Contura G2 and GOM Inspect software. The ES allows for obtaining the castings derived roughness grade number N7. The dimensional deviation between the simulation model of the metal substructure and the manufactured cast is 0.018mm. The arithmetic mean roughness values measured on the casting substructure are from 1.935µm to 2.778µm. The realized developed expert system with the integrated database is fully applicable for the observed hardware and software. Values of the arithmetic mean roughness and dimensional deviation indicate that casting substructures are surface quality, which is more than enough and useful for direct porcelain veneering. The manufacture of the substructure shows that the proposed ES allows the improvement of the design process while reducing the manufacturing time. Copyright © 2017 Elsevier B.V. All rights reserved.

Digital development of products with NX9 for academical areas

NASA Astrophysics Data System (ADS)

Goanta, A. M.

2015-11-01

International competitiveness forced the manufacturing enterprises to look for new ways to accelerate the development of digital products through innovation, global alliances and strategic partnerships. In an environment of global research and development of distributed geographically, all members of the joint teams made up of companies and universities need to access updated and accurate information about products created by any of the type employed, student, teacher. Current design processes involve more complex products consisting of elements of design created by multiple teams, disciplines and suppliers using independent CAD systems. Even when using a 3D CAD mature technology, many companies fail to significantly reduce losses in the process, improve product quality or product type to ensure successful innovations to market arouse interest. These challenges require a radical rethinking of the business model, which belongs to the field of design, which must be based on digital development of products based on integrated files. Through this work, the author has proposed to provide both synthesis and transformations brought news of the integrated NX [1, 2, 3] from Siemens PLM Software 9, following a news results detailed documentary study, and personal results obtained by applying the same version, the digital and integrated development of a product type device test beams. Based on educational license received for NX 9 was made a detailed study of the innovations made by this release, and the application of some of them went to graphical modelling and getting all the documentation of a test device bearing beams. Also, were synthesized in terms of methodology, the steps to take to obtain graphical documentation. The results consist of: 3D models of all parts and assembly 3D model of the three-dimensional constraints of all component parts and not least respectively all drawings and assembly drawing. The most important consequence of the paper is the obtaining of integrated files that can be subjected to further analysis type CAE / CAM / PDM software components by the same company. Additional advantages related files by the synthesis of integrated CAD / CAE / CAM / PDM.

Modular Rocket Engine Control Software (MRECS)

NASA Technical Reports Server (NTRS)

Tarrant, C.; Crook, J.

1998-01-01

The Modular Rocket Engine Control Software (MRECS) Program is a technology demonstration effort designed to advance the state-of-the-art in launch vehicle propulsion systems. Its emphasis is on developing and demonstrating a modular software architecture for advanced engine control systems that will result in lower software maintenance (operations) costs. It effectively accommodates software requirement changes that occur due to hardware technology upgrades and engine development testing. Ground rules directed by MSFC were to optimize modularity and implement the software in the Ada programming language. MRECS system software and the software development environment utilize Commercial-Off-the-Shelf (COTS) products. This paper presents the objectives, benefits, and status of the program. The software architecture, design, and development environment are described. MRECS tasks are defined and timing relationships given. Major accomplishments are listed. MRECS offers benefits to a wide variety of advanced technology programs in the areas of modular software architecture, reuse software, and reduced software reverification time related to software changes. MRECS was recently modified to support a Space Shuttle Main Engine (SSME) hot-fire test. Cold Flow and Flight Readiness Testing were completed before the test was cancelled. Currently, the program is focused on supporting NASA MSFC in accomplishing development testing of the Fastrac Engine, part of NASA's Low Cost Technologies (LCT) Program. MRECS will be used for all engine development testing.

DEM Solutions Develops Answers to Modeling Lunar Dust and Regolith

NASA Technical Reports Server (NTRS)

Dunn, Carol Anne; Calle, Carlos; LaRoche, Richard D.

2010-01-01

With the proposed return to the Moon, scientists like NASA-KSC's Dr. Calle are concerned for a number of reasons. We will be staying longer on the planet's surface, future missions may include dust-raising activities, such as excavation and handling of lunar soil and rock, and we will be sending robotic instruments to do much of the work for us. Understanding more about the chemical and physical properties of lunar dust, how dust particles interact with each other and with equipment surfaces and the role of static electricity build-up on dust particles in the low-humidity lunar environment is imperative to the development of technologies for removing and preventing dust accumulation, and successfully handling lunar regolith. Dr. Calle is currently working on the problems of the electrostatic phenomena of granular and bulk materials as they apply to planetary surfaces, particularly to those of Mars and the Moon, and is heavily involved in developing instrumentation for future planetary missions. With this end in view, the NASA Kennedy Space Center's Innovative Partnerships Program Office partnered with OEM Solutions, Inc. OEM Solutions is a global leader in particle dynamics simulation software, providing custom solutions for use in tackling tough design and process problems related to bulk solids handling. Customers in industries such as pharmaceutical, chemical, mineral, and materials processing as well as oil and gas production, agricultural and construction, and geo-technical engineering use OEM Solutions' EDEM(TradeMark) software to improve the design and operation of their equipment while reducing development costs, time-to-market and operational risk. EDEM is the world's first general-purpose computer-aided engineering (CAE) tool to use state-of-the-art discrete element modeling technology for the simulation and analysis of particle handling and manufacturing operations. With EDEM you'can quickly and easily create a parameterized model of your granular solids system. Computer-aided design (CAD) models of real particles can be imported to obtain an accurate representation of their shape. EDEM(TradeMark) uses particle-scale behavior models to simulate bulk solids behavior. In addition to particle size and shape, the models can account for physical properties of particles along with interaction between particles and with equipment surfaces and surrounding media, as needed to define the physics of a particular process.

Teaching Agile Software Engineering Using Problem-Based Learning

ERIC Educational Resources Information Center

El-Khalili, Nuha H.

2013-01-01

Many studies have reported the utilization of Problem-Based Learning (PBL) in teaching Software Engineering courses. However, these studies have different views of the effectiveness of PBL. This paper presents the design of an Advanced Software Engineering course for undergraduate Software Engineering students that uses PBL to teach them Agile…

Software Engineering Frameworks: Textbooks vs. Student Perceptions

ERIC Educational Resources Information Center

McMaster, Kirby; Hadfield, Steven; Wolthuis, Stuart; Sambasivam, Samuel

2012-01-01

This research examines the frameworks used by Computer Science and Information Systems students at the conclusion of their first semester of study of Software Engineering. A questionnaire listing 64 Software Engineering concepts was given to students upon completion of their first Software Engineering course. This survey was given to samples of…

Performing Verification and Validation in Reuse-Based Software Engineering

NASA Technical Reports Server (NTRS)

Addy, Edward A.

1999-01-01

The implementation of reuse-based software engineering not only introduces new activities to the software development process, such as domain analysis and domain modeling, it also impacts other aspects of software engineering. Other areas of software engineering that are affected include Configuration Management, Testing, Quality Control, and Verification and Validation (V&V). Activities in each of these areas must be adapted to address the entire domain or product line rather than a specific application system. This paper discusses changes and enhancements to the V&V process, in order to adapt V&V to reuse-based software engineering.

The Many Faces of a Software Engineer in a Research Community

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marinovici, Maria C.; Kirkham, Harold

2013-10-14

The ability to gather, analyze and make decisions based on real world data is changing nearly every field of human endeavor. These changes are particularly challenging for software engineers working in a scientific community, designing and developing large, complex systems. To avoid the creation of a communications gap (almost a language barrier), the software engineers should possess an ‘adaptive’ skill. In the science and engineering research community, the software engineers must be responsible for more than creating mechanisms for storing and analyzing data. They must also develop a fundamental scientific and engineering understanding of the data. This paper looks atmore » the many faces that a software engineer should have: developer, domain expert, business analyst, security expert, project manager, tester, user experience professional, etc. Observations made during work on a power-systems scientific software development are analyzed and extended to describe more generic software development projects.« less

Effect of 10-Week Supervised Moderate-Intensity Intermittent vs. Continuous Aerobic Exercise Programs on Vascular Adhesion Molecules in Patients with Heart Failure.

PubMed

Aksoy, Sibel; Findikoglu, Gulin; Ardic, Fusun; Rota, Simin; Dursunoglu, Dursun

2015-10-01

Abnormal expression of cellular adhesion molecules may be related to endothelial dysfunction, a key feature in chronic heart failure. This study compares the effects of 10-wk supervised moderate-intensity continuous aerobic exercise (CAE) and intermittent aerobic exercise (IAE) programs on markers of endothelial damage, disease severity, functional and metabolic status, and quality-of-life in chronic heart failure patients. Fifty-seven patients between 41 and 81 yrs with New York Heart Association class II-III chronic heart failure and with a left ventricular ejection fraction of 35%-55% were randomized into three groups: nonexercising control, CAE, and IAE, which exercised three times a week for 10 wks. Endothelial damage was assessed by serum markers of vascular cell adhesion molecule-1, serum intercellular adhesion molecule-1, and nitric oxide; disease severity was measured by left ventricular ejection fraction and N-terminal probrain natriuretic peptide; metabolic status was evaluated by body composition analysis and lipid profile levels; functional status was evaluated by cardiorespiratory exercise stress test and 6-min walking distance; quality-of-life was assessed with Left Ventricular Dysfunction-36 and Short-Form 36 questionnaires at the baseline and at the end of the 10th week. Significant decreases in serum vascular cell adhesion molecule-1 or serum intercellular adhesion molecule-1 in IAE and CAE groups after training were found, respectively. Resting systolic and diastolic blood pressure, peak systolic and diastolic blood pressure, 6-min walking distance, and the mental health and vitality components of Short-Form 36 improved in the CAE group, whereas left ventricular ejection fraction and 6-min walking distance improved in the IAE group compared with the control group. Both moderate-intensity CAE and IAE programs significantly reduced serum markers of adhesion molecules and prevented the change in VO2 in patients with chronic heart failure.

Collected software engineering papers, volume 2

NASA Technical Reports Server (NTRS)

1983-01-01

Topics addressed include: summaries of the software engineering laboratory (SEL) organization, operation, and research activities; results of specific research projects in the areas of resource models and software measures; and strategies for data collection for software engineering research.

Managing the Software Development Process

NASA Technical Reports Server (NTRS)

Lubelczky, Jeffrey T.; Parra, Amy

1999-01-01

The goal of any software development project is to produce a product that is delivered on time, within the allocated budget, and with the capabilities expected by the customer and unfortunately, this goal is rarely achieved. However, a properly managed project in a mature software engineering environment can consistently achieve this goal. In this paper we provide an introduction to three project success factors, a properly managed project, a competent project manager, and a mature software engineering environment. We will also present an overview of the benefits of a mature software engineering environment based on 24 years of data from the Software Engineering Lab, and suggest some first steps that an organization can take to begin benefiting from this environment. The depth and breadth of software engineering exceeds this paper, various references are cited with a goal of raising awareness and encouraging further investigation into software engineering and project management practices.

Proceedings of the Eighth Annual Software Engineering Workshop

NASA Technical Reports Server (NTRS)

1983-01-01

The four major topics of discussion included: the NASA Software Engineering Laboratory, software testing, human factors in software engineering and software quality assessment. As in the past years, there were 12 position papers presented (3 for each topic) followed by questions and very heavy participation by the general audience.

Use of Soft Computing Technologies For Rocket Engine Control

NASA Technical Reports Server (NTRS)

Trevino, Luis C.; Olcmen, Semih; Polites, Michael

2003-01-01

The problem to be addressed in this paper is to explore how the use of Soft Computing Technologies (SCT) could be employed to further improve overall engine system reliability and performance. Specifically, this will be presented by enhancing rocket engine control and engine health management (EHM) using SCT coupled with conventional control technologies, and sound software engineering practices used in Marshall s Flight Software Group. The principle goals are to improve software management, software development time and maintenance, processor execution, fault tolerance and mitigation, and nonlinear control in power level transitions. The intent is not to discuss any shortcomings of existing engine control and EHM methodologies, but to provide alternative design choices for control, EHM, implementation, performance, and sustaining engineering. The approaches outlined in this paper will require knowledge in the fields of rocket engine propulsion, software engineering for embedded systems, and soft computing technologies (i.e., neural networks, fuzzy logic, and Bayesian belief networks), much of which is presented in this paper. The first targeted demonstration rocket engine platform is the MC-1 (formerly FASTRAC Engine) which is simulated with hardware and software in the Marshall Avionics & Software Testbed laboratory that

Laboratory Performance of the Single-Sided E-A-R (registered trademark) Combat Arms Hearing Protective Earplug

DTIC Science & Technology

2010-01-01

mdividu a eté evalue sans protection auditive ctaye.c port. binaural du protecteur dans chacun des deux modes. Les seuils auditifs en champ hbre...which the ears were: unocciuded (Unocelud), fitted binaurally with the single- sided version of the Combat Arms earplug in the steady state noise mode...CAE SS), and fitted binaurally with the single-sided version of the Combat Arms earplug in the weapons fire mode (CAE WF). The unoccluded condition was

Test & Evaluation Management Guide

DTIC Science & Technology

2012-12-01

The plan for conducting a TRA is provided to the ASD(R&E) by the PM upon approval by the Component Acquisition Executive ( CAE ). A TRA is required...from a UAV at high altitude but only a 5-km range from low altitude. A constraint to prevent tests that would fire a missile from low altitude at a...E. Procedurally, DASD(DT&E) produces an assessment memorandum prior to the IOT&Es OTRR, or for Space Systems, prior to consent to ship. The CAE

Political Connections of the Boards of Directors and Defense Contractors Excessive Profits

DTIC Science & Technology

2013-01-02

have 50 percent higher default rates. Such preferential treatment occurs exclusively in government banks—private banks provide no political favors...83,566,808 388 IN 3577 11 CAE CORP $83,563,697 389 CAE 3690 11 DEL MONTE FOODS COMPANY $77,962,809 419 DLM 2000 11 AMERICAN SCIENCE AND ENGRG...much rule out the possibility of anybody simultaneously serving a high -rank public service role and a top executive role in a private-sector firm. In

A Bibliography of Externally Published Works by the SEI Engineering Techniques Program

DTIC Science & Technology

1992-08-01

media, and virtual reality * model- based engineering * programming languages * reuse * software architectures * software engineering as a discipline...Knowledge- Based Engineering Environments." IEEE Expert 3, 2 (May 1988): 18-23, 26-32. Audience: Practitioner [Klein89b] Klein, D.V. "Comparison of...Terms with Software Reuse Terminology: A Model- Based Approach." ACM SIGSOFT Software Engineering Notes 16, 2 (April 1991): 45-51. Audience: Practitioner

An overview of the small engine component technology (SECT) studies. [commuter, rotorcraft, cruise missile and auxiliary power applications in year 2000

NASA Technical Reports Server (NTRS)

Vanco, M. R.; Wintucky, W. T.; Niedwiecki, R. W.

1986-01-01

The objectives of the joint NASA/Army SECT studies were to identify high payoff technologies for year 2000 small gas turbine engine applications and to provide a technology plan for guiding future research and technology efforts applicable to rotorcraft, commuter and general aviation aircraft and cruise missiles. Competitive contracts were awarded to Allison, AVCO Lycoming, Garrett, Teledyne CAE and Williams International. This paper presents an overview of the contractors' study efforts for the commuter, rotorcraft, cruise missile, and auxiliary power (APU) applications with engines in the 250 to 1,000 horsepower size range. Reference aircraft, missions and engines were selected. Advanced engine configurations and cycles with projected year 2000 component technologies were evaluated and compared with a reference engine selected by the contractor. For typical commuter and rotorcraft applications, fuel savings of 22 percent to 42 percent can be attained. For $1/gallon and $2/gallon fuel, reductions in direct operating cost range from 6 percent to 16 percent and from 11 percent to 17 percent respectively. For subsonic strategic cruise missile applications, fuel savings of 38 percent to 54 percent can be achieved which allows 35 percent to 60 percent increase in mission range and life cycle cost reductions of 40 percent to 56 percent. High payoff technologies have been identified for all applications.

Investigation on the Crack Behaviour in Kevlar 49 Based Composite Materials using Extended Finite Element Method for Aerospace Applications

NASA Astrophysics Data System (ADS)

Handa, Danish; Sekhar Dondapati, Raja; Kumar, Abhinav

2017-08-01

Ductile to brittle transition (DTBT) is extensively observed in materials under cryogenic temperatures, thereby observing brittle failure due to the non-resistance of crack propagation. Owing to its outstanding mechanical and thermal properties, Kevlar 49 composites are widely used in aerospace applications under cryogenic temperatures. Therefore, in this paper, involving the assumption of linear elastic fracture mechanics (LEFM), mechanical characterization of Kevlar 49 composite is done using Extended Finite Element Method (X-FEM) technique in Abaqus/CAE software. Further, the failure of Kevlar 49 composites due to the propagation of crack at room temperature and the cryogenic temperature is investigated. Stress, strain and strain energy density as a function of the width of the Kevlar specimen is predicted, indicates that Kevlar 49 composites are suitable for use under cryogenic temperatures.

A report on NASA software engineering and Ada training requirements

NASA Technical Reports Server (NTRS)

Legrand, Sue; Freedman, Glenn B.; Svabek, L.

1987-01-01

NASA's software engineering and Ada skill base are assessed and information that may result in new models for software engineering, Ada training plans, and curricula are provided. A quantitative assessment which reflects the requirements for software engineering and Ada training across NASA is provided. A recommended implementation plan including a suggested curriculum with associated duration per course and suggested means of delivery is also provided. The distinction between education and training is made. Although it was directed to focus on NASA's need for the latter, the key relationships to software engineering education are also identified. A rationale and strategy for implementing a life cycle education and training program are detailed in support of improved software engineering practices and the transition to Ada.

Miniaturized high throughput detection system for capillary array electrophoresis on chip with integrated light emitting diode array as addressed ring-shaped light source.

PubMed

Ren, Kangning; Liang, Qionglin; Mu, Xuan; Luo, Guoan; Wang, Yiming

2009-03-07

A novel miniaturized, portable fluorescence detection system for capillary array electrophoresis (CAE) on a microfluidic chip was developed, consisting of a scanning light-emitting diode (LED) light source and a single point photoelectric sensor. Without charge coupled detector (CCD), lens, fibers and moving parts, the system was extremely simplified. Pulsed driving of the LED significantly increased the sensitivity, and greatly reduced the power consumption and photobleaching effect. The highly integrated system was robust and easy to use. All the advantages realized the concept of a portable micro-total analysis system (micro-TAS), which could work on a single universal serial bus (USB) port. Compared with traditional CAE detecting systems, the current system could scan the radial capillary array with high scanning rate. An 8-channel CAE of fluorescein isothiocyanate (FITC) labeled arginine (Arg) on chip was demonstrated with this system, resulting in a limit of detection (LOD) of 640 amol.

V&V Within Reuse-Based Software Engineering

NASA Technical Reports Server (NTRS)

Addy, Edward A.

1996-01-01

Verification and Validation (V&V) is used to increase the level of assurance of critical software, particularly that of safety-critical and mission-critical software. V&V is a systems engineering discipline that evaluates the software in a systems context, and is currently applied during the development of a specific application system. In order to bring the effectiveness of V&V to bear within reuse-based software engineering, V&V must be incorporated within the domain engineering process.

Professional Ethics of Software Engineers: An Ethical Framework.

PubMed

Lurie, Yotam; Mark, Shlomo

2016-04-01

The purpose of this article is to propose an ethical framework for software engineers that connects software developers' ethical responsibilities directly to their professional standards. The implementation of such an ethical framework can overcome the traditional dichotomy between professional skills and ethical skills, which plagues the engineering professions, by proposing an approach to the fundamental tasks of the practitioner, i.e., software development, in which the professional standards are intrinsically connected to the ethical responsibilities. In so doing, the ethical framework improves the practitioner's professionalism and ethics. We call this approach Ethical-Driven Software Development (EDSD), as an approach to software development. EDSD manifests the advantages of an ethical framework as an alternative to the all too familiar approach in professional ethics that advocates "stand-alone codes of ethics". We believe that one outcome of this synergy between professional and ethical skills is simply better engineers. Moreover, since there are often different software solutions, which the engineer can provide to an issue at stake, the ethical framework provides a guiding principle, within the process of software development, that helps the engineer evaluate the advantages and disadvantages of different software solutions. It does not and cannot affect the end-product in and of-itself. However, it can and should, make the software engineer more conscious and aware of the ethical ramifications of certain engineering decisions within the process.

Engineering Complex Embedded Systems with State Analysis and the Mission Data System

NASA Technical Reports Server (NTRS)

Ingham, Michel D.; Rasmussen, Robert D.; Bennett, Matthew B.; Moncada, Alex C.

2004-01-01

It has become clear that spacecraft system complexity is reaching a threshold where customary methods of control are no longer affordable or sufficiently reliable. At the heart of this problem are the conventional approaches to systems and software engineering based on subsystem-level functional decomposition, which fail to scale in the tangled web of interactions typically encountered in complex spacecraft designs. Furthermore, there is a fundamental gap between the requirements on software specified by systems engineers and the implementation of these requirements by software engineers. Software engineers must perform the translation of requirements into software code, hoping to accurately capture the systems engineer's understanding of the system behavior, which is not always explicitly specified. This gap opens up the possibility for misinterpretation of the systems engineer s intent, potentially leading to software errors. This problem is addressed by a systems engineering methodology called State Analysis, which provides a process for capturing system and software requirements in the form of explicit models. This paper describes how requirements for complex aerospace systems can be developed using State Analysis and how these requirements inform the design of the system software, using representative spacecraft examples.

Research on Visualization Design Method in the Field of New Media Software Engineering

NASA Astrophysics Data System (ADS)

Deqiang, Hu

2018-03-01

In the new period of increasingly developed science and technology, with the increasingly fierce competition in the market and the increasing demand of the masses, new design and application methods have emerged in the field of new media software engineering, that is, the visualization design method. Applying the visualization design method to the field of new media software engineering can not only improve the actual operation efficiency of new media software engineering but more importantly the quality of software development can be enhanced by means of certain media of communication and transformation; on this basis, the progress and development of new media software engineering in China are also continuously promoted. Therefore, the application of visualization design method in the field of new media software engineering is analysed concretely in this article from the perspective of the overview of visualization design methods and on the basis of systematic analysis of the basic technology.

Cognitive adverse events of topiramate in patients with epilepsy and intellectual disability.

PubMed

Brandt, Christian; Lahr, Denise; May, Theodor W

2015-04-01

Topiramate (TPM) is an effective antiepileptic drug (AED). A high proportion of patients, however, experiences cognitive adverse events (CAEs), especially in verbal fluency, memory spans, and working memory. To our knowledge, CAEs of TPM have not been studied systematically in patients with intellectual disability (ID). This may be due to the fact that many of those patients are not able to follow test instructions properly and that neuropsychological instruments are not validated for that group. Cognitive deterioration in patients with ID may thus easily be overlooked. Topiramate is in frequent use in persons with ID. We included 26 consecutive patients with epilepsy and ID in this observational study who had undergone neuropsychological examinations as part of clinical routine before and after the introduction of TPM into the therapeutic regimen (n=4) or before and after the withdrawal of TPM (n=22). Examinations under TPM showed reduced cognitive speed, reduced verbal memory, reduced verbal fluency, and reduced flexibility compared to examinations without TPM. Despite some limitations (especially small sample size, high interindividual variation of the results dependent on the degree of ID, effects of other - limited - changes in the therapeutic regimen), our study indicates that TPM in persons with epilepsy and ID may lead to CAEs comparable to those in persons with normal intelligence. Neuropsychological testing is mandatory in order not to miss CAEs that might severely impair quality of life. Copyright © 2015 Elsevier Inc. All rights reserved.

BeamDyn: A High-Fidelity Wind Turbine Blade Solver in the FAST Modular Framework: Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Q.; Sprague, M.; Jonkman, J.

2015-01-01

BeamDyn, a Legendre-spectral-finite-element implementation of geometrically exact beam theory (GEBT), was developed to meet the design challenges associated with highly flexible composite wind turbine blades. In this paper, the governing equations of GEBT are reformulated into a nonlinear state-space form to support its coupling within the modular framework of the FAST wind turbine computer-aided engineering (CAE) tool. Different time integration schemes (implicit and explicit) were implemented and examined for wind turbine analysis. Numerical examples are presented to demonstrate the capability of this new beam solver. An example analysis of a realistic wind turbine blade, the CX-100, is also presented asmore » validation.« less

State analysis requirements database for engineering complex embedded systems

NASA Technical Reports Server (NTRS)

Bennett, Matthew B.; Rasmussen, Robert D.; Ingham, Michel D.

2004-01-01

It has become clear that spacecraft system complexity is reaching a threshold where customary methods of control are no longer affordable or sufficiently reliable. At the heart of this problem are the conventional approaches to systems and software engineering based on subsystem-level functional decomposition, which fail to scale in the tangled web of interactions typically encountered in complex spacecraft designs. Furthermore, there is a fundamental gap between the requirements on software specified by systems engineers and the implementation of these requirements by software engineers. Software engineers must perform the translation of requirements into software code, hoping to accurately capture the systems engineer's understanding of the system behavior, which is not always explicitly specified. This gap opens up the possibility for misinterpretation of the systems engineer's intent, potentially leading to software errors. This problem is addressed by a systems engineering tool called the State Analysis Database, which provides a tool for capturing system and software requirements in the form of explicit models. This paper describes how requirements for complex aerospace systems can be developed using the State Analysis Database.

The TAME Project: Towards improvement-oriented software environments

NASA Technical Reports Server (NTRS)

Basili, Victor R.; Rombach, H. Dieter

1988-01-01

Experience from a dozen years of analyzing software engineering processes and products is summarized as a set of software engineering and measurement principles that argue for software engineering process models that integrate sound planning and analysis into the construction process. In the TAME (Tailoring A Measurement Environment) project at the University of Maryland, such an improvement-oriented software engineering process model was developed that uses the goal/question/metric paradigm to integrate the constructive and analytic aspects of software development. The model provides a mechanism for formalizing the characterization and planning tasks, controlling and improving projects based on quantitative analysis, learning in a deeper and more systematic way about the software process and product, and feeding the appropriate experience back into the current and future projects. The TAME system is an instantiation of the TAME software engineering process model as an ISEE (integrated software engineering environment). The first in a series of TAME system prototypes has been developed. An assessment of experience with this first limited prototype is presented including a reassessment of its initial architecture.

Impacts of Technological Changes in the Cyber Environment on Software/Systems Engineering Workforce Development

DTIC Science & Technology

2010-04-01

for decoupled parallel development Ref: Barry Boehm 12 Impacts of Technological Changes in the Cyber Environment on Software/Systems Engineering... Pressman , R.S., Software Engineering: A Practitioner’s Approach, 13 Impacts of Technological Changes in the Cyber Environment on Software/Systems

Software And Systems Engineering Risk Management

DTIC Science & Technology

2010-04-01

RSKM 2004 COSO Enterprise RSKM Framework 2006 ISO/IEC 16085 Risk Management Process 2008 ISO/IEC 12207 Software Lifecycle Processes 2009 ISO/IEC...1 Software And Systems Engineering Risk Management John Walz VP Technical and Conferences Activities, IEEE Computer Society Vice-Chair Planning...Software & Systems Engineering Standards Committee, IEEE Computer Society US TAG to ISO TMB Risk Management Working Group Systems and Software

Proceedings of the 19th Annual Software Engineering Workshop

NASA Technical Reports Server (NTRS)

1994-01-01

The Software Engineering Laboratory (SEL) is an organization sponsored by NASA/GSFC and created to investigate the effectiveness of software engineering technologies when applied to the development of applications software. The goals of the SEL are: (1) to understand the software development process in the GSFC environment; (2) to measure the effects of various methodologies, tools, and models on this process; and (3) to identify and then to apply successful development practices. The activities, findings, and recommendations of the SEL are recorded in the Software Engineering Laboratory Series, a continuing series of reports that include this document.

Data collection procedures for the Software Engineering Laboratory (SEL) database

NASA Technical Reports Server (NTRS)

Heller, Gerard; Valett, Jon; Wild, Mary

1992-01-01

This document is a guidebook to collecting software engineering data on software development and maintenance efforts, as practiced in the Software Engineering Laboratory (SEL). It supersedes the document entitled Data Collection Procedures for the Rehosted SEL Database, number SEL-87-008 in the SEL series, which was published in October 1987. It presents procedures to be followed on software development and maintenance projects in the Flight Dynamics Division (FDD) of Goddard Space Flight Center (GSFC) for collecting data in support of SEL software engineering research activities. These procedures include detailed instructions for the completion and submission of SEL data collection forms.

Annotated bibliography of Software Engineering Laboratory literature

NASA Technical Reports Server (NTRS)

1985-01-01

An annotated bibliography of technical papers, documents, and memorandums produced by or related to the Software Engineering Laboratory is presented. More than 100 publications are summarized. These publications are summarized. These publications cover many areas of software engineering and range from research reports to software documentation. This document has been updated and reorganized substantially since the original version (SEL-82-006, November 1982). All materials are grouped into five general subject areas for easy reference: (1) the software engineering laboratory; (2) software tools; (3) models and measures; (4) technology evaluations; and (5) data collection. An index further classifies these documents by specific topic.

Modular Rocket Engine Control Software (MRECS)

NASA Technical Reports Server (NTRS)

Tarrant, Charlie; Crook, Jerry

1997-01-01

The Modular Rocket Engine Control Software (MRECS) Program is a technology demonstration effort designed to advance the state-of-the-art in launch vehicle propulsion systems. Its emphasis is on developing and demonstrating a modular software architecture for a generic, advanced engine control system that will result in lower software maintenance (operations) costs. It effectively accommodates software requirements changes that occur due to hardware. technology upgrades and engine development testing. Ground rules directed by MSFC were to optimize modularity and implement the software in the Ada programming language. MRECS system software and the software development environment utilize Commercial-Off-the-Shelf (COTS) products. This paper presents the objectives and benefits of the program. The software architecture, design, and development environment are described. MRECS tasks are defined and timing relationships given. Major accomplishment are listed. MRECS offers benefits to a wide variety of advanced technology programs in the areas of modular software, architecture, reuse software, and reduced software reverification time related to software changes. Currently, the program is focused on supporting MSFC in accomplishing a Space Shuttle Main Engine (SSME) hot-fire test at Stennis Space Center and the Low Cost Boost Technology (LCBT) Program.

Software Engineering Improvement Plan

NASA Technical Reports Server (NTRS)

2006-01-01

In performance of this task order, bd Systems personnel provided support to the Flight Software Branch and the Software Working Group through multiple tasks related to software engineering improvement and to activities of the independent Technical Authority (iTA) Discipline Technical Warrant Holder (DTWH) for software engineering. To ensure that the products, comments, and recommendations complied with customer requirements and the statement of work, bd Systems personnel maintained close coordination with the customer. These personnel performed work in areas such as update of agency requirements and directives database, software effort estimation, software problem reports, a web-based process asset library, miscellaneous documentation review, software system requirements, issue tracking software survey, systems engineering NPR, and project-related reviews. This report contains a summary of the work performed and the accomplishments in each of these areas.

Software engineering as an engineering discipline

NASA Technical Reports Server (NTRS)

Freedman, Glenn B.

1988-01-01

The purpose of this panel is to explore the emerging field of software engineering from a variety of perspectives: university programs; industry training and definition; government development; and technology transfer. In doing this, the panel will address the issues of distinctions among software engineering, computer science, and computer hardware engineering as they relate to the challenges of large, complex systems.

Development of Low-cost plotter for educational purposes using Arduino

NASA Astrophysics Data System (ADS)

Karthik, Siriparapu; Thirumal Reddy, Palwai; Marimuthu, K. Prakash

2017-08-01

With the development of CAD/CAM/CAE concept to product realization time has reduced drastically. Most of the activities such as design, drafting, and visualizations are carried out using high-end computers and commercial software. This has reduced the overall lead-time to market. It is important in the current scenario to equip the students with knowledge of advanced technological developments in order to use them effectively. However, the cost associated with the systems are very high which is not affordable to students. The present work is an attempt to build a low-cost plotter integrating some of the software that are available and components got from scrapped electronic devices. Here the authors are introducing G-code plotter with 3-axis which can implement the given g-code in 2D plane (X-Y). Lifting pen and adjusting to the base component is in the Z-axis. All conventional plotting devices existing until date are costly and need basic knowledge before operating. Our aim is to make students understand the working of plotter and the usage of G-code, achieving this at a much affordable cost. Arduino Uno controls the stepper motors, which can accurately plot the given dimensions.

Applying formal methods and object-oriented analysis to existing flight software

NASA Technical Reports Server (NTRS)

Cheng, Betty H. C.; Auernheimer, Brent

1993-01-01

Correctness is paramount for safety-critical software control systems. Critical software failures in medical radiation treatment, communications, and defense are familiar to the public. The significant quantity of software malfunctions regularly reported to the software engineering community, the laws concerning liability, and a recent NRC Aeronautics and Space Engineering Board report additionally motivate the use of error-reducing and defect detection software development techniques. The benefits of formal methods in requirements driven software development ('forward engineering') is well documented. One advantage of rigorously engineering software is that formal notations are precise, verifiable, and facilitate automated processing. This paper describes the application of formal methods to reverse engineering, where formal specifications are developed for a portion of the shuttle on-orbit digital autopilot (DAP). Three objectives of the project were to: demonstrate the use of formal methods on a shuttle application, facilitate the incorporation and validation of new requirements for the system, and verify the safety-critical properties to be exhibited by the software.

Aeroelastic Modeling of Offshore Turbines and Support Structures in Hurricane-Prone Regions (Poster)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Damiani, R.

US offshore wind turbines (OWTs) will likely have to contend with hurricanes and the associated loading conditions. Current industry standards do not account for these design load cases (DLCs), thus a new approach is required to guarantee that the OWTs achieve an appropriate level of reliability. In this study, a sequentially coupled aero-hydro-servo-elastic modeling technique was used to address two design approaches: 1.) The ABS (American Bureau of Shipping) approach; and 2.) The Hazard Curve or API (American Petroleum Institute) approach. The former employs IEC partial load factors (PSFs) and 100-yr return-period (RP) metocean events. The latter allows setting PSFsmore » and RP to a prescribed level of system reliability. The 500-yr RP robustness check (appearing in [2] and [3] upcoming editions) is a good indicator of the target reliability for L2 structures. CAE tools such as NREL's FAST and Bentley's' SACS (offshore analysis and design software) can be efficiently coupled to simulate system loads under hurricane DLCs. For this task, we augmented the latest FAST version (v. 8) to include tower aerodynamic drag that cannot be ignored in hurricane DLCs. In this project, a 6 MW turbine was simulated on a typical 4-legged jacket for a mid-Atlantic site. FAST-calculated tower base loads were fed to SACS at the interface level (transition piece); SACS added hydrodynamic and wind loads on the exposed substructure, and calculated mudline overturning moments, and member and joint utilization. Results show that CAE tools can be effectively used to compare design approaches for the design of OWTs in hurricane regions and to achieve a well-balanced design, where reliability levels and costs are optimized.« less

Proceedings of the Annual Ada Software Engineering Education and Training Symposium (3rd) Held in Denver, Colorado on June 14-16, 1988

DTIC Science & Technology

1988-06-01

Based Software Engineering Project Course .............. 83 SSoftware Engineering, Software Engineering Concepts: The Importance of Object-Based...quality assurance, and independent system testing . The Chief Programmer is responsible for all software development activities, including prototyping...during the Requirements Analysis phase, the Preliminary Design, the Detailed Design, Coding and Unit Testing , CSC Integration and Testing , and informal

Political Connections of the Boards of Directors and Defense Contractors’ Excessive Profits

DTIC Science & Technology

2013-04-01

found that “political firms borrow 45 percent more and have 50 percent higher default rates. Such preferential treatment occurs exclusively in...SOUP CO.  $88,645,010  367 CPB 2030  11 INTERMEC CORPORATION  $83,566,808  388 IN 3577  11 CAE  CORP  $83,563,697  389 CAE 3690  11 DEL MONTE FOODS...pretty much rule out the possibility of anybody simultaneously serving a high - rank public service role and a top executive role in a private-sector firm

Proceedings of the Fifteenth Annual Software Engineering Workshop

NASA Technical Reports Server (NTRS)

1990-01-01

The Software Engineering Laboratory (SEL) is an organization sponsored by GSFC and created for the purpose of investigating the effectiveness of software engineering technologies when applied to the development of applications software. The goals of the SEL are: (1) to understand the software development process in the GSFC environment; (2) to measure the effect of various methodologies, tools, and models on this process; and (3) to identify and then to apply successful development practices. Fifteen papers were presented at the Fifteenth Annual Software Engineering Workshop in five sessions: (1) SEL at age fifteen; (2) process improvement; (3) measurement; (4) reuse; and (5) process assessment. The sessions were followed by two panel discussions: (1) experiences in implementing an effective measurement program; and (2) software engineering in the 1980's. A summary of the presentations and panel discussions is given.

Multidisciplinary and Active/Collaborative Approaches in Teaching Requirements Engineering

ERIC Educational Resources Information Center

Rosca, Daniela

2005-01-01

The requirements engineering course is a core component of the curriculum for the Master's in Software Engineering programme, at Monmouth University (MU). It covers the process, methods and tools specific to this area, together with the corresponding software quality issues. The need to produce software engineers with strong teamwork and…

A Knowledge Engineering Approach to Analysis and Evaluation of Construction Schedules

DTIC Science & Technology

1990-02-01

software engineering discipline focusing on constructing KBSs. It is an incremental and cyclical process that requires the interaction of a domain expert(s...the U.S. Army Coips of Engineers ; and (3) the project management software developer, represented by Pinnell Engineering , Inc. Since the primary...the programming skills necessary to convert the raw knowledge intn a form a computer can understand. knowledge engineering : The software engineering

Questioning the Role of Requirements Engineering in the Causes of Safety-Critical Software Failures

NASA Technical Reports Server (NTRS)

Johnson, C. W.; Holloway, C. M.

2006-01-01

Many software failures stem from inadequate requirements engineering. This view has been supported both by detailed accident investigations and by a number of empirical studies; however, such investigations can be misleading. It is often difficult to distinguish between failures in requirements engineering and problems elsewhere in the software development lifecycle. Further pitfalls arise from the assumption that inadequate requirements engineering is a cause of all software related accidents for which the system fails to meet its requirements. This paper identifies some of the problems that have arisen from an undue focus on the role of requirements engineering in the causes of major accidents. The intention is to provoke further debate within the emerging field of forensic software engineering.

Computer systems and software engineering

NASA Technical Reports Server (NTRS)

Mckay, Charles W.

1988-01-01

The High Technologies Laboratory (HTL) was established in the fall of 1982 at the University of Houston Clear Lake. Research conducted at the High Tech Lab is focused upon computer systems and software engineering. There is a strong emphasis on the interrelationship of these areas of technology and the United States' space program. In Jan. of 1987, NASA Headquarters announced the formation of its first research center dedicated to software engineering. Operated by the High Tech Lab, the Software Engineering Research Center (SERC) was formed at the University of Houston Clear Lake. The High Tech Lab/Software Engineering Research Center promotes cooperative research among government, industry, and academia to advance the edge-of-knowledge and the state-of-the-practice in key topics of computer systems and software engineering which are critical to NASA. The center also recommends appropriate actions, guidelines, standards, and policies to NASA in matters pertinent to the center's research. Results of the research conducted at the High Tech Lab/Software Engineering Research Center have given direction to many decisions made by NASA concerning the Space Station Program.

Annotated bibliography of Software Engineering Laboratory (SEL) literature

NASA Technical Reports Server (NTRS)

Card, D.

1982-01-01

An annotated bibliography of technical papers, documents, and memorandums produced by or related to the Software Engineering Laboratory is presented. More than 75 publications are summarized. An index of these publications by subject is also included. These publications cover many areas of software engineering and range from research reports to software documentation.

Towards a Controlled Vocabulary on Software Engineering Education

ERIC Educational Resources Information Center

Pizard, Sebastián; Vallespir, Diego

2017-01-01

Software engineering is the discipline that develops all the aspects of the production of software. Although there are guidelines about what topics to include in a software engineering curricula, it is usually unclear which are the best methods to teach them. In any science discipline the construction of a classification schema is a common…

AADL and Model-based Engineering

DTIC Science & Technology

2014-10-20

and MBE Feiler, Oct 20, 2014 © 2014 Carnegie Mellon University We Rely on Software for Safe Aircraft Operation Embedded software systems ...D eveloper Compute Platform Runtime Architecture Application Software Embedded SW System Engineer Data Stream Characteristics Latency...confusion Hardware Engineer Why do system level failures still occur despite fault tolerance techniques being deployed in systems ? Embedded software

Intelligent Agents for Design and Synthesis Environments: My Summary

NASA Technical Reports Server (NTRS)

Norvig, Peter

1999-01-01

This presentation gives a summary of intelligent agents for design synthesis environments. We'll start with the conclusions, and work backwards to justify them. First, an important assumption is that agents (whatever they are) are good for software engineering. This is especially true for software that operates in an uncertain, changing environment. The "real world" of physical artifacts is like that: uncertain in what we can measure, changing in that things are always breaking down, and we must interact with non-software entities. The second point is that software engineering techniques can contribute to good design. There may have been a time when we wanted to build simple artifacts containing little or no software. But modern aircraft and spacecraft are complex, and rely on a great deal of software. So better software engineering leads to better designed artifacts, especially when we are designing a series of related artifacts and can amortize the costs of software development. The third point is that agents are especially useful for design tasks, above and beyond their general usefulness for software engineering, and the usefulness of software engineering to design.

NASA software documentation standard software engineering program

NASA Technical Reports Server (NTRS)

1991-01-01

The NASA Software Documentation Standard (hereinafter referred to as Standard) can be applied to the documentation of all NASA software. This Standard is limited to documentation format and content requirements. It does not mandate specific management, engineering, or assurance standards or techniques. This Standard defines the format and content of documentation for software acquisition, development, and sustaining engineering. Format requirements address where information shall be recorded and content requirements address what information shall be recorded. This Standard provides a framework to allow consistency of documentation across NASA and visibility into the completeness of project documentation. This basic framework consists of four major sections (or volumes). The Management Plan contains all planning and business aspects of a software project, including engineering and assurance planning. The Product Specification contains all technical engineering information, including software requirements and design. The Assurance and Test Procedures contains all technical assurance information, including Test, Quality Assurance (QA), and Verification and Validation (V&V). The Management, Engineering, and Assurance Reports is the library and/or listing of all project reports.

Improving Software Engineering on NASA Projects

NASA Technical Reports Server (NTRS)

Crumbley, Tim; Kelly, John C.

2010-01-01

Software Engineering Initiative: Reduces risk of software failure -Increases mission safety. More predictable software cost estimates and delivery schedules. Smarter buyer of contracted out software. More defects found and removed earlier. Reduces duplication of efforts between projects. Increases ability to meet the challenges of evolving software technology.

Automating Software Design Metrics.

DTIC Science & Technology

1984-02-01

INTRODUCTION 1 ", ... 0..1 1.2 HISTORICAL PERSPECTIVE High quality software is of interest to both the software engineering com- munity and its users. As...contributions of many other software engineering efforts, most notably [MCC 77] and [Boe 83b], which have defined and refined a framework for quantifying...AUTOMATION OF DESIGN METRICS Software metrics can be useful within the context of an integrated soft- ware engineering environment. The purpose of this

Use of Soft Computing Technologies for a Qualitative and Reliable Engine Control System for Propulsion Systems

NASA Technical Reports Server (NTRS)

Trevino, Luis; Brown, Terry; Crumbley, R. T. (Technical Monitor)

2001-01-01

The problem to be addressed in this paper is to explore how the use of Soft Computing Technologies (SCT) could be employed to improve overall vehicle system safety, reliability, and rocket engine performance by development of a qualitative and reliable engine control system (QRECS). Specifically, this will be addressed by enhancing rocket engine control using SCT, innovative data mining tools, and sound software engineering practices used in Marshall's Flight Software Group (FSG). The principle goals for addressing the issue of quality are to improve software management, software development time, software maintenance, processor execution, fault tolerance and mitigation, and nonlinear control in power level transitions. The intent is not to discuss any shortcomings of existing engine control methodologies, but to provide alternative design choices for control, implementation, performance, and sustaining engineering, all relative to addressing the issue of reliability. The approaches outlined in this paper will require knowledge in the fields of rocket engine propulsion (system level), software engineering for embedded flight software systems, and soft computing technologies (i.e., neural networks, fuzzy logic, data mining, and Bayesian belief networks); some of which are briefed in this paper. For this effort, the targeted demonstration rocket engine testbed is the MC-1 engine (formerly FASTRAC) which is simulated with hardware and software in the Marshall Avionics & Software Testbed (MAST) laboratory that currently resides at NASA's Marshall Space Flight Center, building 4476, and is managed by the Avionics Department. A brief plan of action for design, development, implementation, and testing a Phase One effort for QRECS is given, along with expected results. Phase One will focus on development of a Smart Start Engine Module and a Mainstage Engine Module for proper engine start and mainstage engine operations. The overall intent is to demonstrate that by employing soft computing technologies, the quality and reliability of the overall scheme to engine controller development is further improved and vehicle safety is further insured. The final product that this paper proposes is an approach to development of an alternative low cost engine controller that would be capable of performing in unique vision spacecraft vehicles requiring low cost advanced avionics architectures for autonomous operations from engine pre-start to engine shutdown.

Modeling of coupled thermodynamic and geomechanical performance of underground compressed air energy storage in lined rock caverns

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rutqvist, Jonny; Kim, Hyung-Mok; Ryu, Dong-Woo

We applied coupled nonisothermal, multiphase fluid flow and geomechanical numerical modeling to study the coupled thermodynamic and geomechanical performance of underground compressed air energy storage (CAES) in concrete-lined rock caverns. The paper focuses on CAES in lined caverns at relatively shallow depth (e.g., 100 m depth) in which a typical CAES operational pressure of 5 to 8 MPa is significantly higher than both ambient fluid pressure and in situ stress. We simulated a storage operation that included cyclic compression and decompression of air in the cavern, and investigated how pressure, temperature and stress evolve over several months of operation. Wemore » analyzed two different lining options, both with a 50 cm thick low permeability concrete lining, but in one case with an internal synthetic seal such as steel or rubber. For our simulated CAES system, the thermodynamic analysis showed that 96.7% of the energy injected during compression could be recovered during subsequent decompression, while 3.3% of the energy was lost by heat conduction to the surrounding media. Our geomechanical analysis showed that tensile effective stresses as high as 8 MPa could develop in the lining as a result of the air pressure exerted on the inner surface of the lining, whereas thermal stresses were relatively smaller and compressive. With the option of an internal synthetic seal, the maximum effective tensile stress was reduced from 8 to 5 MPa, but was still in substantial tension. We performed one simulation in which the tensile tangential stresses resulted in radial cracks and air leakage though the lining. This air leakage, however, was minor (about 0.16% of the air mass loss from one daily compression) in terms of CAES operational efficiency, and did not significantly impact the overall energy balance of the system. However, despite being minor in terms of energy balance, the air leakage resulted in a distinct pressure increase in the surrounding rock that could be quickly detected using pressure monitoring outside the concrete lining.« less

A Review of the Suitability of Available Computer Aided Software Engineering (CASE) Tools for the Small Software Development Environment

DTIC Science & Technology

1989-07-11

LITERATURE CITED [Boeh73] Boehm, Barry W., "Software and its Impact: A Quantitative Assessment," Datamation, 19, 5, (May 1973), pp 48-59. [Boeh76...Boehm, Barry W., "Software Engineering," IEEE Transactions on Computers, C-25, 12, (December 1976), pp 1226-1241. [Boeh81a] Boehm, Barry W., Software...Engineering Economics, Prentice-Hall, Inc., Englewood Cliffs, NJ, (1981). [Boeh8lb] Boehm, Barry W., "An Experiment in Small Scale Application Software

Happy software developers solve problems better: psychological measurements in empirical software engineering

PubMed Central

Wang, Xiaofeng; Abrahamsson, Pekka

2014-01-01

For more than thirty years, it has been claimed that a way to improve software developers’ productivity and software quality is to focus on people and to provide incentives to make developers satisfied and happy. This claim has rarely been verified in software engineering research, which faces an additional challenge in comparison to more traditional engineering fields: software development is an intellectual activity and is dominated by often-neglected human factors (called human aspects in software engineering research). Among the many skills required for software development, developers must possess high analytical problem-solving skills and creativity for the software construction process. According to psychology research, affective states—emotions and moods—deeply influence the cognitive processing abilities and performance of workers, including creativity and analytical problem solving. Nonetheless, little research has investigated the correlation between the affective states, creativity, and analytical problem-solving performance of programmers. This article echoes the call to employ psychological measurements in software engineering research. We report a study with 42 participants to investigate the relationship between the affective states, creativity, and analytical problem-solving skills of software developers. The results offer support for the claim that happy developers are indeed better problem solvers in terms of their analytical abilities. The following contributions are made by this study: (1) providing a better understanding of the impact of affective states on the creativity and analytical problem-solving capacities of developers, (2) introducing and validating psychological measurements, theories, and concepts of affective states, creativity, and analytical-problem-solving skills in empirical software engineering, and (3) raising the need for studying the human factors of software engineering by employing a multidisciplinary viewpoint. PMID:24688866

Happy software developers solve problems better: psychological measurements in empirical software engineering.

PubMed

Graziotin, Daniel; Wang, Xiaofeng; Abrahamsson, Pekka

2014-01-01

For more than thirty years, it has been claimed that a way to improve software developers' productivity and software quality is to focus on people and to provide incentives to make developers satisfied and happy. This claim has rarely been verified in software engineering research, which faces an additional challenge in comparison to more traditional engineering fields: software development is an intellectual activity and is dominated by often-neglected human factors (called human aspects in software engineering research). Among the many skills required for software development, developers must possess high analytical problem-solving skills and creativity for the software construction process. According to psychology research, affective states-emotions and moods-deeply influence the cognitive processing abilities and performance of workers, including creativity and analytical problem solving. Nonetheless, little research has investigated the correlation between the affective states, creativity, and analytical problem-solving performance of programmers. This article echoes the call to employ psychological measurements in software engineering research. We report a study with 42 participants to investigate the relationship between the affective states, creativity, and analytical problem-solving skills of software developers. The results offer support for the claim that happy developers are indeed better problem solvers in terms of their analytical abilities. The following contributions are made by this study: (1) providing a better understanding of the impact of affective states on the creativity and analytical problem-solving capacities of developers, (2) introducing and validating psychological measurements, theories, and concepts of affective states, creativity, and analytical-problem-solving skills in empirical software engineering, and (3) raising the need for studying the human factors of software engineering by employing a multidisciplinary viewpoint.

Software technology insertion: A study of success factors

NASA Technical Reports Server (NTRS)

Lydon, Tom

1990-01-01

Managing software development in large organizations has become increasingly difficult due to increasing technical complexity, stricter government standards, a shortage of experienced software engineers, competitive pressure for improved productivity and quality, the need to co-develop hardware and software together, and the rapid changes in both hardware and software technology. The 'software factory' approach to software development minimizes risks while maximizing productivity and quality through standardization, automation, and training. However, in practice, this approach is relatively inflexible when adopting new software technologies. The methods that a large multi-project software engineering organization can use to increase the likelihood of successful software technology insertion (STI), especially in a standardized engineering environment, are described.

Study of the influence of the cutting temperature on the magnitude of the contact forces in the machining fixtures

NASA Astrophysics Data System (ADS)

Cioată, V. G.; Kiss, I.; Alexa, V.; Raţiu, S. A.; Racov, M.

2018-01-01

In the machining process, the workpieces are installed in machining fixtures in order to establish a strictly determined position with the cutting tool or its trajectory. During the cutting process, the weight of the workpiece, the forces and moments of inertia, cutting forces and moments, clamping forces, the heat released during the cutting process determine the contact forces between the locators and the workpiece. The magnitude of these forces is important because too large value can destroy the surface of the workpiece, and a too small value can cause the workpiece to slip on the locators or even the loss of the contact with the workpiece. Both situations must be avoided. The paper presents a study, realized with CAE software, regarding the influence of the cutting temperature on the magnitude of the contact forces in a machining fixture for the milling a rectangular workpiece.

Defense AT&L Magazine: A Publication of the Defense Acquisition University. Volume 34, Number 3, DAU 184

DTIC Science & Technology

2005-01-01

developed a partnership with the Defense Acquisition University to in- tegrate DISA’s systems engineering processes, software , and network...in place, with processes being implemented: deployment management; systems engineering ; software engineering ; configuration man- agement; test and...CSS systems engineering is a transition partner with Carnegie Mellon University’s Software Engineering Insti- tute and its work on the capability

Some pharmacological effects of cinnamon and ginger herbs in obese diabetic rats

PubMed Central

Shalaby, Mostafa Abbas; Saifan, Hamed Yahya

2014-01-01

Aims: The present study was designed to assess some pharmacological effects of cinnamon (CAE) and ginger (GAE) aqueous extracts in obese diabetic rats, and to elucidate the potential mechanisms. Materials and Methods: Forty-two Sprague-Dawley rats were randomized into 6 equal groups. Group 1 was a negative control and the other groups were rendered obese by feeding rats on high-fat diet for 4 weeks. The obese rats were subcutaneously injected with alloxan for 5*days to induce diabetes. Group 2 was a positive control, and Groups 3, 4, 5 and 6 were orally given CAE in doses 200 and 400 mg/kg and GAE in the same doses, respectively for 6 weeks. Blood samples were collected for serum biochemical analyses. Kidneys were dissected out to assay activity of tissue antioxidant enzymes: Superoxide dismutase, glutathione peroxidase and catalase. Results: CAE and GAE significantly reduced body weight and body fat mass; normalized serum levels of liver enzymes; improved lipid profile; decreased blood glucose and leptin and increased insulin serum levels in obese diabetic rats. Both extracts also increased activity of kidney antioxidant enzymes. Conclusion: CAE and GAE exhibit anti-obesity, hepatoprotective, hypolipidemic, antidiabetic and anti-oxidant effects in obese diabetic rats. These results confirm the previous reports on both extracts. The potential mechanisms underlying these effects are fully discussed and clarified. Our results affirm the traditional use of cinnamon and ginger for treating patients suffering from obesity and diabetes. The obese diabetic rat model used in this study is a novel animal model used in pharmacology researches. PMID:26401364

Shuttle avionics software trials, tribulations and success

NASA Technical Reports Server (NTRS)

Henderson, O. L.

1985-01-01

The early problems and the solutions developed to provide the required quality software needed to support the space shuttle engine development program are described. The decision to use a programmable digital control system on the space shuttle engine was primarily based upon the need for a flexible control system capable of supporting the total engine mission on a large complex pump fed engine. The mission definition included all control phases from ground checkout through post shutdown propellant dumping. The flexibility of the controller through reprogrammable software allowed the system to respond to the technical challenges and innovation required to develop both the engine and controller hardware. This same flexibility, however, placed a severe strain on the capability of the software development and verification organization. The overall development program required that the software facility accommodate significant growth in both the software requirements and the number of software packages delivered. This challenge was met by reorganization and evolution in the process of developing and verifying software.

Shaping Software Engineering Curricula Using Open Source Communities: A Case Study

ERIC Educational Resources Information Center

Bowring, James; Burke, Quinn

2016-01-01

This paper documents four years of a novel approach to teaching a two-course sequence in software engineering as part of the ABET-accredited computer science curriculum at the College of Charleston. This approach is team-based and centers on learning software engineering in the context of open source software projects. In the first course, teams…

Proceedings of the Thirteenth Annual Software Engineering Workshop

NASA Technical Reports Server (NTRS)

1988-01-01

Topics covered in the workshop included studies and experiments conducted in the Software Engineering Laboratory (SEL), a cooperative effort of NASA Goddard Space Flight Center, the University of Maryland, and Computer Sciences Corporation; software models; software products; and software tools.

High-Performance Multiplex SNP Analysis of Three Hemochromatosis-Related Mutations With Capillary Array Electrophoresis Microplates

PubMed Central

Medintz, Igor; Wong, Wendy W.; Berti, Lorenzo; Shiow, Lawrence; Tom, Jennifer; Scherer, James; Sensabaugh, George; Mathies, Richard A.

2001-01-01

An assay is described for high-throughput single nucleotide polymorphism (SNP) genotyping on a microfabricated capillary array electrophoresis (CAE) microchip. The assay targets the three common variants at the HFE locus associated with the genetic disease hereditary hemochromatosis (HHC). The assay employs allele-specific PCR (ASPCR) for the C282Y (845g->a), H63D (187c->g), and S65C (193a->t) variants using fluorescently-labeled energy-transfer (ET) allele-specific primers. Using a 96-channel radial CAE microplate, the labeled ASPCR products generated from 96 samples in a reference Caucasian population are simultaneously separated with single-base-pair resolution and genotyped in under 10 min. Detection is accomplished with a laser-excited rotary four-color fluorescence scanner. The allele-specific amplicons are differentiated on the basis of both their size and the color of the label emission. This study is the first demonstration of the combined use of ASPCR with ET primers and microfabricated radial CAE microplates to perform multiplex SNP analyses in a clinically relevant population. PMID:11230165

Changing Arctic ecosystems: resilience of caribou to climatic shifts in the Arctic

USGS Publications Warehouse

Gustine, David D.; Adams, Layne G.; Whalen, Mary E.; Pearce, John M.

2014-01-01

The U.S. Geological Survey (USGS) Changing Arctic Ecosystems (CAE) initiative strives to inform key resource management decisions for Arctic Alaska by providing scientific information and forecasts for current and future ecosystem response to a warming climate. Over the past 5 years, a focal area for the USGS CAE initiative has been the North Slope of Alaska. This region has experienced a warming trend over the past 60 years, yet the rate of change has been varied across the North Slope, leading scientists to question the future response and resilience of wildlife populations, such as caribou (Rangifer tarandus), that rely on tundra habitats for forage. Future changes in temperature and precipitation to coastal wet sedge and upland low shrub tundra are expected, with unknown consequences for caribou that rely on these plant communities for food. Understanding how future environmental change may affect caribou migration, nutrition, and reproduction is a focal question being addressed by the USGS CAE research. Results will inform management agencies in Alaska and people that rely on caribou for food.

The value of compressed air energy storage with wind in transmission-constrained electric power systems

DOE PAGES

Denholm, Paul; Sioshansi, Ramteen

2009-05-05

In this paper, we examine the potential advantages of co-locating wind and energy storage to increase transmission utilization and decrease transmission costs. Co-location of wind and storage decreases transmission requirements, but also decreases the economic value of energy storage compared to locating energy storage at the load. This represents a tradeoff which we examine to estimate the transmission costs required to justify moving storage from load-sited to wind-sited in three different locations in the United States. We examined compressed air energy storage (CAES) in three “wind by wire” scenarios with a variety of transmission and CAES sizes relative to amore » given amount of wind. In the sites and years evaluated, the optimal amount of transmission ranges from 60% to 100% of the wind farm rating, with the optimal amount of CAES equal to 0–35% of the wind farm rating, depending heavily on wind resource, value of electricity in the local market, and the cost of natural gas.« less

Lessons from Iowa : development of a 270 megawatt compressed air energy storage project in midwest Independent System Operator : a study for the DOE Energy Storage Systems Program.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holst, Kent; Huff, Georgianne; Schulte, Robert H.

2012-01-01

The Iowa Stored Energy Park was an innovative, 270 Megawatt, $400 million compressed air energy storage (CAES) project proposed for in-service near Des Moines, Iowa, in 2015. After eight years in development the project was terminated because of site geological limitations. However, much was learned in the development process regarding what it takes to do a utility-scale, bulk energy storage facility and coordinate it with regional renewable wind energy resources in an Independent System Operator (ISO) marketplace. Lessons include the costs and long-term economics of a CAES facility compared to conventional natural gas-fired generation alternatives; market, legislative, and contract issuesmore » related to enabling energy storage in an ISO market; the importance of due diligence in project management; and community relations and marketing for siting of large energy projects. Although many of the lessons relate to CAES applications in particular, most of the lessons learned are independent of site location or geology, or even the particular energy storage technology involved.« less

Averting Denver Airports on a Chip

NASA Technical Reports Server (NTRS)

Sullivan, Kevin J.

1995-01-01

As a result of recent advances in software engineering capabilities, we are now in a more stable environment. De-facto hardware and software standards are emerging. Work on software architecture and design patterns signals a consensus on the importance of early system-level design decisions, and agreements on the uses of certain paradigmatic software structures. We now routinely build systems that would have been risky or infeasible a few years ago. Unfortunately, technological developments threaten to destabilize software design again. Systems designed around novel computing and peripheral devices will spark ambitious new projects that will stress current software design and engineering capabilities. Micro-electro-mechanical systems (MEMS) and related technologies provide the physical basis for new systems with the potential to produce this kind of destabilizing effect. One important response to anticipated software engineering and design difficulties is carefully directed engineering-scientific research. Two specific problems meriting substantial research attention are: A lack of sufficient means to build software systems by generating, extending, specializing, and integrating large-scale reusable components; and a lack of adequate computational and analytic tools to extend and aid engineers in maintaining intellectual control over complex software designs.

Software Management Metrics

DTIC Science & Technology

1988-05-01

obtained from Dr. Barry Boehm’s Software 5650, Contract No. F19628-86-C-O001, Engineering Economics [1] and from T. J. ESD/MITRE Software Center Acquisition...of References 1. Boehm, Barry W., SoJtware Engineering 3. Halstead, M. H., Elements of SoJhtare Economics, Englewood Cliffs, New Science, New York...1983, pp. 639-648. 35 35 - Bibliography Beizer, B., Software System Testing and Pressman , Roger S., Software Engineering:QualtyO Assurance, New York: Van

SOFTWARE ENGINEERING INSTITUTE (SEI)

EPA Science Inventory

The Software Engineering Institute (SEI) is a federally funded research and development center established in 1984 by the U.S. Department of Defense and operated by Carnegie Mellon University. SEI has a broad charter to provide leadership in the practice of software engineering t...

7 Processes that Enable NASA Software Engineering Technologies: Value-Added Process Engineering

NASA Technical Reports Server (NTRS)

Housch, Helen; Godfrey, Sally

2011-01-01

The presentation reviews Agency process requirements and the purpose, benefits, and experiences or seven software engineering processes. The processes include: product integration, configuration management, verification, software assurance, measurement and analysis, requirements management, and planning and monitoring.

Methodology for automating software systems. Task 1 of the foundations for automating software systems

NASA Technical Reports Server (NTRS)

Moseley, Warren

1989-01-01

The early stages of a research program designed to establish an experimental research platform for software engineering are described. Major emphasis is placed on Computer Assisted Software Engineering (CASE). The Poor Man's CASE Tool is based on the Apple Macintosh system, employing available software including Focal Point II, Hypercard, XRefText, and Macproject. These programs are functional in themselves, but through advanced linking are available for operation from within the tool being developed. The research platform is intended to merge software engineering technology with artificial intelligence (AI). In the first prototype of the PMCT, however, the sections of AI are not included. CASE tools assist the software engineer in planning goals, routes to those goals, and ways to measure progress. The method described allows software to be synthesized instead of being written or built.

IEEE Conference on Software Engineering Education and Training (CSEE&T 2012) Proceedings (25th, Nanjing, Jiangsu, China, April 17-19, 2012)

ERIC Educational Resources Information Center

IEEE Conference on Software Engineering Education and Training, Proceedings (MS), 2012

2012-01-01

The Conference on Software Engineering Education and Training (CSEE&T) is the premier international peer-reviewed conference, sponsored by the Institute of Electrical and Electronics Engineers, Inc. (IEEE) Computer Society, which addresses all major areas related to software engineering education, training, and professionalism. This year, as…

Modelling of diesel engine fuelled with biodiesel using engine simulation software

NASA Astrophysics Data System (ADS)

Said, Mohd Farid Muhamad; Said, Mazlan; Aziz, Azhar Abdul

2012-06-01

This paper is about modelling of a diesel engine that operates using biodiesel fuels. The model is used to simulate or predict the performance and combustion of the engine by simplified the geometry of engine component in the software. The model is produced using one-dimensional (1D) engine simulation software called GT-Power. The fuel properties library in the software is expanded to include palm oil based biodiesel fuels. Experimental works are performed to investigate the effect of biodiesel fuels on the heat release profiles and the engine performance curves. The model is validated with experimental data and good agreement is observed. The simulation results show that combustion characteristics and engine performances differ when biodiesel fuels are used instead of no. 2 diesel fuel.

Milestones in Software Engineering and Knowledge Engineering History: A Comparative Review

PubMed Central

del Águila, Isabel M.; Palma, José; Túnez, Samuel

2014-01-01

We present a review of the historical evolution of software engineering, intertwining it with the history of knowledge engineering because “those who cannot remember the past are condemned to repeat it.” This retrospective represents a further step forward to understanding the current state of both types of engineerings; history has also positive experiences; some of them we would like to remember and to repeat. Two types of engineerings had parallel and divergent evolutions but following a similar pattern. We also define a set of milestones that represent a convergence or divergence of the software development methodologies. These milestones do not appear at the same time in software engineering and knowledge engineering, so lessons learned in one discipline can help in the evolution of the other one. PMID:24624046

Milestones in software engineering and knowledge engineering history: a comparative review.

PubMed

del Águila, Isabel M; Palma, José; Túnez, Samuel

2014-01-01

We present a review of the historical evolution of software engineering, intertwining it with the history of knowledge engineering because "those who cannot remember the past are condemned to repeat it." This retrospective represents a further step forward to understanding the current state of both types of engineerings; history has also positive experiences; some of them we would like to remember and to repeat. Two types of engineerings had parallel and divergent evolutions but following a similar pattern. We also define a set of milestones that represent a convergence or divergence of the software development methodologies. These milestones do not appear at the same time in software engineering and knowledge engineering, so lessons learned in one discipline can help in the evolution of the other one.

A software engineering approach to expert system design and verification

NASA Technical Reports Server (NTRS)

Bochsler, Daniel C.; Goodwin, Mary Ann

1988-01-01

Software engineering design and verification methods for developing expert systems are not yet well defined. Integration of expert system technology into software production environments will require effective software engineering methodologies to support the entire life cycle of expert systems. The software engineering methods used to design and verify an expert system, RENEX, is discussed. RENEX demonstrates autonomous rendezvous and proximity operations, including replanning trajectory events and subsystem fault detection, onboard a space vehicle during flight. The RENEX designers utilized a number of software engineering methodologies to deal with the complex problems inherent in this system. An overview is presented of the methods utilized. Details of the verification process receive special emphasis. The benefits and weaknesses of the methods for supporting the development life cycle of expert systems are evaluated, and recommendations are made based on the overall experiences with the methods.

Consistent Evolution of Software Artifacts and Non-Functional Models

DTIC Science & Technology

2014-11-14

induce bad software performance)? 15. SUBJECT TERMS EOARD, Nano particles, Photo-Acoustic Sensors, Model-Driven Engineering ( MDE ), Software Performance...Università degli Studi dell’Aquila, Via Vetoio, 67100 L’Aquila, Italy Email: vittorio.cortellessa@univaq.it Web : http: // www. di. univaq. it/ cortelle/ Phone...Model-Driven Engineering ( MDE ), Software Performance Engineering (SPE), Change Propagation, Performance Antipatterns. For sake of readability of the

A self-referential HOWTO on release engineering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Galassi, Mark C.

Release engineering is a fundamental part of the software development cycle: it is the point at which quality control is exercised and bug fixes are integrated. The way in which software is released also gives the end user her first experience of a software package, while in scientific computing release engineering can guarantee reproducibility. For these reasons and others, the release process is a good indicator of the maturity and organization of a development team. Software teams often do not put in place a release process at the beginning. This is unfortunate because the team does not have early andmore » continuous execution of test suites, and it does not exercise the software in the same conditions as the end users. I describe an approach to release engineering based on the software tools developed and used by the GNU project, together with several specific proposals related to packaging and distribution. I do this in a step-by-step manner, demonstrating how this very paper is written and built using proper release engineering methods. Because many aspects of release engineering are not exercised in the building of the paper, the accompanying software repository also contains examples of software libraries.« less

The Effect of AOP on Software Engineering, with Particular Attention to OIF and Event Quantification

NASA Technical Reports Server (NTRS)

Havelund, Klaus; Filman, Robert; Korsmeyer, David (Technical Monitor)

2003-01-01

We consider the impact of Aspect-Oriented Programming on Software Engineering, and, in particular, analyze two AOP systems, one of which does component wrapping and the other, quantification over events, for their software engineering effects.

Second Generation Product Line Engineering Takes Hold in the DoD

DTIC Science & Technology

2014-01-01

Feature- Oriented Domain Analysis ( FODA ) Feasibility Study” (CMU/SEI-90- TR-021, ADA235785). Pittsburgh, PA: Software Engineering Institute...software product line engineering and software architecture documentation and analysis . Clements is co-author of three practitioner-oriented books about

Collected Software Engineering Papers, Volume 10

NASA Technical Reports Server (NTRS)

1992-01-01

This document is a collection of selected technical papers produced by participants in the Software Engineering Laboratory (SEL) from Oct. 1991 - Nov. 1992. The purpose of the document is to make available, in one reference, some results of SEL research that originally appeared in a number of different forums. Although these papers cover several topics related to software engineering, they do not encompass the entire scope of SEL activities and interests. Additional information about the SEL and its research efforts may be obtained from the sources listed in the bibliography at the end of this document. For the convenience of this presentation, the 11 papers contained here are grouped into 5 major sections: (1) the Software Engineering Laboratory; (2) software tools studies; (3) software models studies; (4) software measurement studies; and (5) Ada technology studies.

An Architecture, System Engineering, and Acquisition Approach for Space System Software Resiliency

NASA Astrophysics Data System (ADS)

Phillips, Dewanne Marie

Software intensive space systems can harbor defects and vulnerabilities that may enable external adversaries or malicious insiders to disrupt or disable system functions, risking mission compromise or loss. Mitigating this risk demands a sustained focus on the security and resiliency of the system architecture including software, hardware, and other components. Robust software engineering practices contribute to the foundation of a resilient system so that the system "can take a hit to a critical component and recover in a known, bounded, and generally acceptable period of time". Software resiliency must be a priority and addressed early in the life cycle development to contribute a secure and dependable space system. Those who develop, implement, and operate software intensive space systems must determine the factors and systems engineering practices to address when investing in software resiliency. This dissertation offers methodical approaches for improving space system resiliency through software architecture design, system engineering, increased software security, thereby reducing the risk of latent software defects and vulnerabilities. By providing greater attention to the early life cycle phases of development, we can alter the engineering process to help detect, eliminate, and avoid vulnerabilities before space systems are delivered. To achieve this objective, this dissertation will identify knowledge, techniques, and tools that engineers and managers can utilize to help them recognize how vulnerabilities are produced and discovered so that they can learn to circumvent them in future efforts. We conducted a systematic review of existing architectural practices, standards, security and coding practices, various threats, defects, and vulnerabilities that impact space systems from hundreds of relevant publications and interviews of subject matter experts. We expanded on the system-level body of knowledge for resiliency and identified a new software architecture framework and acquisition methodology to improve the resiliency of space systems from a software perspective with an emphasis on the early phases of the systems engineering life cycle. This methodology involves seven steps: 1) Define technical resiliency requirements, 1a) Identify standards/policy for software resiliency, 2) Develop a request for proposal (RFP)/statement of work (SOW) for resilient space systems software, 3) Define software resiliency goals for space systems, 4) Establish software resiliency quality attributes, 5) Perform architectural tradeoffs and identify risks, 6) Conduct architecture assessments as part of the procurement process, and 7) Ascertain space system software architecture resiliency metrics. Data illustrates that software vulnerabilities can lead to opportunities for malicious cyber activities, which could degrade the space mission capability for the user community. Reducing the number of vulnerabilities by improving architecture and software system engineering practices can contribute to making space systems more resilient. Since cyber-attacks are enabled by shortfalls in software, robust software engineering practices and an architectural design are foundational to resiliency, which is a quality that allows the system to "take a hit to a critical component and recover in a known, bounded, and generally acceptable period of time". To achieve software resiliency for space systems, acquirers and suppliers must identify relevant factors and systems engineering practices to apply across the lifecycle, in software requirements analysis, architecture development, design, implementation, verification and validation, and maintenance phases.

Evan Weaver | NREL

Science.gov Websites

Evan Weaver Photo of Evan Weaver Evan Weaver Researcher III-Software Engineering Evan.Weaver , he works as a software engineer developing whole-building energy modeling tools. Prior to joining NREL, he worked in the biomedical industry as a software engineer, specializing in graphical user

Requirements Engineering in Building Climate Science Software

ERIC Educational Resources Information Center

Batcheller, Archer L.

2011-01-01

Software has an important role in supporting scientific work. This dissertation studies teams that build scientific software, focusing on the way that they determine what the software should do. These requirements engineering processes are investigated through three case studies of climate science software projects. The Earth System Modeling…

Glossary of Software Engineering Laboratory terms

NASA Technical Reports Server (NTRS)

1983-01-01

A glossary of terms used in the Software Engineering Laboratory (SEL) is given. The terms are defined within the context of the software development environment for flight dynamics at the Goddard Space Flight Center. A concise reference for clarifying the language employed in SEL documents and data collection forms is given. Basic software engineering concepts are explained and standard definitions for use by SEL personnel are established.

Software Reporting Metrics. Revision 2.

DTIC Science & Technology

1985-11-01

MITRE Corporation and ESD. Some of the data has been obtained from Dr. Barry Boehm’s Software Engineering Economics (Ref. 1). Thanks are also given to...data level control management " SP = structured programming Barry W. Boehm, Software Engineering Economics, &©1981, p. 122. Reprinted by permission of...investigated and implemented in future prototypes. 43 REFERENCES For further reading: " 1. Boehm, Barry W. Software Engineering Economics; Englewood

Toward Reusable Graphics Components in Ada

DTIC Science & Technology

1993-03-01

Then alternatives for obtaining well- engineered reusable software components were examined. Finally, the alternatives were analyzed, and the most...reusable software components. Chapter 4 describes detailed design and implementation strategies in building a well- engineered reusable set of components in...study. 2.2 The Object-Oriented Paradigm 2.2.1 The Need for Object-Oriented Techniques. Among software engineers the software crisis is a well known

Object oriented development of engineering software using CLIPS

NASA Technical Reports Server (NTRS)

Yoon, C. John

1991-01-01

Engineering applications involve numeric complexity and manipulations of a large amount of data. Traditionally, numeric computation has been the concern in developing an engineering software. As engineering application software became larger and more complex, management of resources such as data, rather than the numeric complexity, has become the major software design problem. Object oriented design and implementation methodologies can improve the reliability, flexibility, and maintainability of the resulting software; however, some tasks are better solved with the traditional procedural paradigm. The C Language Integrated Production System (CLIPS), with deffunction and defgeneric constructs, supports the procedural paradigm. The natural blending of object oriented and procedural paradigms has been cited as the reason for the popularity of the C++ language. The CLIPS Object Oriented Language's (COOL) object oriented features are more versatile than C++'s. A software design methodology based on object oriented and procedural approaches appropriate for engineering software, and to be implemented in CLIPS was outlined. A method for sensor placement for Space Station Freedom is being implemented in COOL as a sample problem.

Software requirements specification for the GIS-T/ISTEA pooled fund study phase C linear referencing engine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Amai, W.; Espinoza, J. Jr.; Fletcher, D.R.

1997-06-01

This Software Requirements Specification (SRS) describes the features to be provided by the software for the GIS-T/ISTEA Pooled Fund Study Phase C Linear Referencing Engine project. This document conforms to the recommendations of IEEE Standard 830-1984, IEEE Guide to Software Requirements Specification (Institute of Electrical and Electronics Engineers, Inc., 1984). The software specified in this SRS is a proof-of-concept implementation of the Linear Referencing Engine as described in the GIS-T/ISTEA pooled Fund Study Phase B Summary, specifically Sheet 13 of the Phase B object model. The software allows an operator to convert between two linear referencing methods and a datummore » network.« less

A Software Engineering Approach based on WebML and BPMN to the Mediation Scenario of the SWS Challenge

NASA Astrophysics Data System (ADS)

Brambilla, Marco; Ceri, Stefano; Valle, Emanuele Della; Facca, Federico M.; Tziviskou, Christina

Although Semantic Web Services are expected to produce a revolution in the development of Web-based systems, very few enterprise-wide design experiences are available; one of the main reasons is the lack of sound Software Engineering methods and tools for the deployment of Semantic Web applications. In this chapter, we present an approach to software development for the Semantic Web based on classical Software Engineering methods (i.e., formal business process development, computer-aided and component-based software design, and automatic code generation) and on semantic methods and tools (i.e., ontology engineering, semantic service annotation and discovery).

Software Engineering Education: Some Important Dimensions

ERIC Educational Resources Information Center

Mishra, Alok; Cagiltay, Nergiz Ercil; Kilic, Ozkan

2007-01-01

Software engineering education has been emerging as an independent and mature discipline. Accordingly, various studies are being done to provide guidelines for curriculum design. The main focus of these guidelines is around core and foundation courses. This paper summarizes the current problems of software engineering education programs. It also…

Software Engineering Laboratory (SEL) data base reporting software user's guide and system description. Volume 1: Introduction and user's guide

NASA Technical Reports Server (NTRS)

1983-01-01

Reporting software programs provide formatted listings and summary reports of the Software Engineering Laboratory (SEL) data base contents. The operating procedures and system information for 18 different reporting software programs are described. Sample output reports from each program are provided.

Software Engineering Laboratory (SEL) data base reporting software user's guide and system description. Volume 2: Program descriptions

NASA Technical Reports Server (NTRS)

1983-01-01

The structure and functions of each reporting software program for the Software Engineering Laboratory data base are described. Baseline diagrams, module descriptions, and listings of program generation files are included.

Software engineering standards and practices

NASA Technical Reports Server (NTRS)

Durachka, R. W.

1981-01-01

Guidelines are presented for the preparation of a software development plan. The various phases of a software development project are discussed throughout its life cycle including a general description of the software engineering standards and practices to be followed during each phase.

Socio-Cultural Challenges in Global Software Engineering Education

ERIC Educational Resources Information Center

Hoda, Rashina; Babar, Muhammad Ali; Shastri, Yogeshwar; Yaqoob, Humaa

2017-01-01

Global software engineering education (GSEE) is aimed at providing software engineering (SE) students with knowledge, skills, and understanding of working in globally distributed arrangements so they can be prepared for the global SE (GSE) paradigm. It is important to understand the challenges involved in GSEE for improving the quality and…

Experiences with Integrating Simulation into a Software Engineering Curriculum

ERIC Educational Resources Information Center

Bollin, Andreas; Hochmuller, Elke; Mittermeir, Roland; Samuelis, Ladislav

2012-01-01

Software Engineering education must account for a broad spectrum of knowledge and skills software engineers will be required to apply throughout their professional life. Covering all the topics in depth within a university setting is infeasible due to curricular constraints as well as due to the inherent differences between educational…

An Engineering Context for Software Engineering

DTIC Science & Technology

2008-09-01

medium in which I can plant the ideas from this dissertation. I have also written a book on requirements development that is used at NPS by myself and...Addison-Wesley, Anniversary ed., 1995. [Bry00] Bryant, A., “Metaphor, Myth, and Mimicry : The Bases of Software Engineering,” Annals of Software

The Center for Astronomy Education (CAE) and Our NSF Funded CCLI Phase III Collaboration of Astronomy Teaching Scholars (CATS) Program: Updates to Our New Community-Based Model for Astronomy Education Research

NASA Astrophysics Data System (ADS)

Brissenden, Gina; Impey, C.; Prather, E. E.; Lee, K. M.; CATS

2010-01-01

The Center for Astronomy Education (CAE) has been devoted to improving teaching & learning in Astro 101 by creating research-validated curriculum & assessment instruments for use in Astro 101 & by providing Astro 101 instructors professional development opportunities to increase their pedagogical content knowledge & instructional skills at implementing these curricula & assessment materials. To create sustainability and further expand this work, CAE, in collaboration with other national leaders in astronomy education & research, developed the Collaboration of Astronomy Teaching Scholars (CATS) Program. The primary goals of CATS are to: 1) increase the number of Astro 101 instructors conducting fundamental research in astronomy education 2) increase the amount of research-validated curriculum & assessment instruments available for use in Astro 101 3) increase the number of people prepared to develop & conduct their own CAE Teaching Excellence Workshops In our second year we have concluded a national study assessing the contribution students’ personal characteristics make to student learning gains and the effectiveness of interactive learning strategies. We have results from our classroom research validation study on the use of the "ClassAction” electronic learning system. We have begun creation of an assessment instrument designed specifically for Astro 101 to evaluate the effectiveness of our instruction in improving students’ attitudes & beliefs about science, and which is being informed by several of our studies and community input. We have also begun field-testing of our Solar System Concept Inventory. Additionally research into students’ beliefs and reasoning difficulties on topics in Cosmology is underway. We acknowledge the NSF for funding under Award No. 0715517, a CCLI Phase III Grant for the Collaboration of Astronomy Teaching Scholars (CATS) Program.

The effects of cognitive activity combined with active extremity exercise on balance, walking activity, memory level and quality of life of an older adult sample with dementia.

PubMed

Yoon, Jung Eun; Lee, Suk Min; Lim, Hee Sung; Kim, Tae Hoon; Jeon, Ji Kyeng; Mun, Mee Hyang

2013-12-01

[Purpose] The purpose of this study was to compare the effectiveness of cognitive activity combined with active physical exercise for a sample of older adults with dementia. [Subjects] A convenience sample of 30 patients with dementia (Mini-Mental State Examination score between 16 and 23) was used. Participants were randomly allocated to one of two groups: cognitive activity combined with physical exercise CAE, n=11), and only cognitive activity CA, n=9). [Methods] Both groups participated in a therapeutic exercise program for 30 minutes, three days a week for 12 weeks. The CAE group performed an additional exercise for 30 minutes a day, three days a week for 12 weeks. A Wii Balance Board (WBB, Nintendo, Japan) was used to evaluate postural sway as an assessment of balance. The Berg Balance Scale (BBS) and Modified Falls Efficacy Scale (MFES) were used to assess dynamic balance abilities. The Timed Up-and-Go test (TUG) was used to assess gait, and the Digit Span Test (DST) and 7 Minute Screening Test (7MST) were used to measure memory performance. The Mini-Mental Status Exam-Korean version (MMSE-K), Kenny Self-Care Evaluation (KSCE), and Short Geriatric Depression Scale (GDS) were used to assess quality of life (QOL). [Results] There were significant beneficial effects of the therapeutic program on balance (velocity in EOWB, path length in ECNB, BBS, and MMFE), QOL (MMSE-KC, GDS, KSCE), and memory performance (DSB) in the CAE group compared to CA group, and between pre-test and post-test. [Conclusion] A 12-week CAE program resulted in improvements in balance, memory and QOL. Therefore, some older adults with dementia have the ability to acquire effective skills relevant to daily living.

Characterizing Excavation Damaged Zone and Stability of Pressurized Lined Rock Caverns for Underground Compressed Air Energy Storage

NASA Astrophysics Data System (ADS)

Kim, Hyung-Mok; Rutqvist, Jonny; Jeong, Ju-Hwan; Choi, Byung-Hee; Ryu, Dong-Woo; Song, Won-Kyong

2013-09-01

In this paper, we investigate the influence of the excavation damaged zone (EDZ) on the geomechanical performance of compressed air energy storage (CAES) in lined rock caverns. We conducted a detailed characterization of the EDZ in rock caverns that have been excavated for a Korean pilot test program on CAES in (concrete) lined rock caverns at shallow depth. The EDZ was characterized by measurements of P- and S-wave velocities and permeability across the EDZ and into undisturbed host rock. Moreover, we constructed an in situ concrete lining model and conducted permeability measurements in boreholes penetrating the concrete, through the EDZ and into the undisturbed host rock. Using the site-specific conditions and the results of the EDZ characterization, we carried out a model simulation to investigate the influence of the EDZ on the CAES performance, in particular related to geomechanical responses and stability. We used a modeling approach including coupled thermodynamic multiphase flow and geomechanics, which was proven to be useful in previous generic CAES studies. Our modeling results showed that the potential for inducing tensile fractures and air leakage through the concrete lining could be substantially reduced if the EDZ around the cavern could be minimized. Moreover, the results showed that the most favorable design for reducing the potential for tensile failure in the lining would be a relatively compliant concrete lining with a tight inner seal, and a relatively stiff (uncompliant) host rock with a minimized EDZ. Because EDZ compliance depends on its compressibility (or modulus) and thickness, care should be taken during drill and blast operations to minimize the damage to the cavern walls.

Comparative analysis of background EEG activity in childhood absence epilepsy during valproate treatment: a standardized, low-resolution, brain electromagnetic tomography (sLORETA) study.

PubMed

Shin, Jung-Hyun; Eom, Tae-Hoon; Kim, Young-Hoon; Chung, Seung-Yun; Lee, In-Goo; Kim, Jung-Min

2017-07-01

Valproate (VPA) is an antiepileptic drug (AED) used for initial monotherapy in treating childhood absence epilepsy (CAE). EEG might be an alternative approach to explore the effects of AEDs on the central nervous system. We performed a comparative analysis of background EEG activity during VPA treatment by using standardized, low-resolution, brain electromagnetic tomography (sLORETA) to explore the effect of VPA in patients with CAE. In 17 children with CAE, non-parametric statistical analyses using sLORETA were performed to compare the current density distribution of four frequency bands (delta, theta, alpha, and beta) between the untreated and treated condition. Maximum differences in current density were found in the left inferior frontal gyrus for the delta frequency band (log-F-ratio = -1.390, P > 0.05), the left medial frontal gyrus for the theta frequency band (log-F-ratio = -0.940, P > 0.05), the left inferior frontal gyrus for the alpha frequency band (log-F-ratio = -0.590, P > 0.05), and the left anterior cingulate for the beta frequency band (log-F-ratio = -1.318, P > 0.05). However, none of these differences were significant (threshold log-F-ratio = ±1.888, P < 0.01; threshold log-F-ratio = ±1.722, P < 0.05). Because EEG background is accepted as normal in CAE, VPA would not be expected to significantly change abnormal thalamocortical oscillations on a normal EEG background. Therefore, our results agree with currently accepted concepts but are not consistent with findings in some previous studies.

Electrohydrodynamics of a viscous drop with inertia.

PubMed

Nganguia, H; Young, Y-N; Layton, A T; Lai, M-C; Hu, W-F

2016-05-01

Most of the existing numerical and theoretical investigations on the electrohydrodynamics of a viscous drop have focused on the creeping Stokes flow regime, where nonlinear inertia effects are neglected. In this work we study the inertia effects on the electrodeformation of a viscous drop under a DC electric field using a novel second-order immersed interface method. The inertia effects are quantified by the Ohnesorge number Oh, and the electric field is characterized by an electric capillary number Ca_{E}. Below the critical Ca_{E}, small to moderate electric field strength gives rise to steady equilibrium drop shapes. We found that, at a fixed Ca_{E}, inertia effects induce larger deformation for an oblate drop than a prolate drop, consistent with previous results in the literature. Moreover, our simulations results indicate that inertia effects on the equilibrium drop deformation are dictated by the direction of normal electric stress on the drop interface: Larger drop deformation is found when the normal electric stress points outward, and smaller drop deformation is found otherwise. To our knowledge, such inertia effects on the equilibrium drop deformation has not been reported in the literature. Above the critical Ca_{E}, no steady equilibrium drop deformation can be found, and often the drop breaks up into a number of daughter droplets. In particular, our Navier-Stokes simulations show that, for the parameters we use, (1) daughter droplets are larger in the presence of inertia, (2) the drop deformation evolves more rapidly compared to creeping flow, and (3) complex distribution of electric stresses for drops with inertia effects. Our results suggest that normal electric pressure may be a useful tool in predicting drop pinch-off in oblate deformations.

Effects of cholinergic system of dorsal hippocampus of rats on MK-801 induced anxiolytic-like behavior.

PubMed

Zarrindast, Mohammad Reza; Nasehi, Mohammad; Piri, Morteza; Heidari, Negar

2011-11-14

Some investigations have shown that the glutamate receptors play a critical role in cognitive processes such as learning and anxiety. The possible involvement of the cholinergic system of the dorsal hippocampus in the anxiolytic-like response induced by MK-801, NMDA receptor antagonist, was investigated in the present study. Male Wistar rats were used in the elevated plus maze apparatus to test the parameters: open arm time (%OAT), open arm entries (%OAE), close arm time (%CAT), close arm entries (%CAE) and other exploratory behaviors (locomotor activity, grooming, rearing and defecation) of anxiety-like response. The data indicated that intra-CA1 administration of MK-801 increased %OAT (2μg/rat) and %OAE (1 and 2μg/rat) while decreased %CAT and %CAE and did not alter other exploratory behaviors, indicating an anxiolytic-like effect. Moreover, intra-hippocampal injections of mecamylamine, a cholinergic receptor antagonists (2μg/rat) and scopolamine (4μg/rat), by themselves, 5min before testing, increased %OAT and %OAE but decreased %CAT and %CAE and did not alter locomotor activity and other exploratory behaviors, suggesting an anxiolytic-like effect. On the other hand, intra-CA1 co-administration of an ineffective dose of scopolamine (3μg/rat), but not mecamylamine (1μg/rat), with an ineffective dose of MK-801 (0.5μg/rat) increased %OAT and %OAE and decreased %CAT and %CAE. The data may indicate the possible involvement of the cholinergic system of the CA1 in the anxiolytic-like response induced by MK-801. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Hypobaric Control of Ethylene-Induced Leaf Senescence in Intact Plants of Phaseolus vulgaris L. 1

PubMed Central

Nilsen, Karl N.; Hodges, Clinton F.

1983-01-01

A controlled atmospheric-environment system (CAES) designed to sustain normal or hypobaric ambient growing conditions was developed, described, and evaluated for its effectiveness as a research tool capable of controlling ethylene-induced leaf senescence in intact plants of Phaseolus vulgaris L. Senescence was prematurely-induced in primary leaves by treatment with 30 parts per million ethephon. Ethephon-derived endogenous ethylene reached peak levels within 6 hours at 26°C. Total endogenous ethylene levels then temporarily stabilized at approximately 1.75 microliters per liter from 6 to 24 hours. Thereafter, a progressive rise in ethylene resulted from leaf tissue metabolism and release. Throughout the study, the endogenous ethylene content of ethephon-treated leaves was greater than that of nontreated leaves. Subjecting ethephon-treated leaves to atmospheres of 200 millibars, with O2 and CO2 compositions set to approximate normal atmospheric partial pressures, prevented chlorophyll loss. Alternately, subjecting ethephon-treated plants to 200 millibars of air only partially prevented chlorophyll loss. Hypobaric conditions (200 millibars), with O2 and CO2 at normal atmospheric availability, could be delayed until 48 hours after ethephon treatment and still prevent most leaf senescence. In conclusion, hypobaric conditions established and maintained within the CAES prevented ethylene-induced senescence (chlorosis) in intact plants, provided O2 and CO2 partial pressures were maintained at levels approximating normal ambient availability. An unexpected increase in endogenous ethylene was detected within nontreated control leaves 48 hours subsequent to relocation from winter greenhouse conditions (latitude, 42°00″ N) to the CAES operating at normal ambient pressure. The longer photoperiod and/or higher temperature utilized within the CAES are hypothesized to influence ethylene metabolism directly and growth-promotive processes (e.g. response thresholds) indirectly. PMID:16662806

Selection of software for mechanical engineering undergraduates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cheah, C. T.; Yin, C. S.; Halim, T.

A major problem with the undergraduate mechanical course is the limited exposure of students to software packages coupled with the long learning curve on the existing software packages. This work proposes the use of appropriate software packages for the entire mechanical engineering curriculum to ensure students get sufficient exposure real life design problems. A variety of software packages are highlighted as being suitable for undergraduate work in mechanical engineering, e.g. simultaneous non-linear equations; uncertainty analysis; 3-D modeling software with the FEA; analysis tools for the solution of problems in thermodynamics, fluid mechanics, mechanical system design, and solid mechanics.

Proceedings of the Twenty-Fourth Annual Software Engineering Workshop

NASA Technical Reports Server (NTRS)

2000-01-01

On December 1 and 2, the Software Engineering Laboratory (SEL), a consortium composed of NASA/Goddard, the University of Maryland, and CSC, held the 24th Software Engineering Workshop (SEW), the last of the millennium. Approximately 240 people attended the 2-day workshop. Day 1 was composed of four sessions: International Influence of the Software Engineering Laboratory; Object Oriented Testing and Reading; Software Process Improvement; and Space Software. For the first session, three internationally known software process experts discussed the influence of the SEL with respect to software engineering research. In the Space Software session, prominent representatives from three different NASA sites- GSFC's Marti Szczur, the Jet Propulsion Laboratory's Rick Doyle, and the Ames Research Center IV&V Facility's Lou Blazy- discussed the future of space software in their respective centers. At the end of the first day, the SEW sponsored a reception at the GSFC Visitors' Center. Day 2 also provided four sessions: Using the Experience Factory; A panel discussion entitled "Software Past, Present, and Future: Views from Government, Industry, and Academia"; Inspections; and COTS. The day started with an excellent talk by CSC's Frank McGarry on "Attaining Level 5 in CMM Process Maturity." Session 2, the panel discussion on software, featured NASA Chief Information Officer Lee Holcomb (Government), our own Jerry Page (Industry), and Mike Evangelist of the National Science Foundation (Academia). Each presented his perspective on the most important developments in software in the past 10 years, in the present, and in the future.

Integrated multidisciplinary CAD/CAE environment for micro-electro-mechanical systems (MEMS)

NASA Astrophysics Data System (ADS)

Przekwas, Andrzej J.

1999-03-01

Computational design of MEMS involves several strongly coupled physical disciplines, including fluid mechanics, heat transfer, stress/deformation dynamics, electronics, electro/magneto statics, calorics, biochemistry and others. CFDRC is developing a new generation multi-disciplinary CAD systems for MEMS using high-fidelity field solvers on unstructured, solution-adaptive grids for a full range of disciplines. The software system, ACE + MEMS, includes all essential CAD tools; geometry/grid generation for multi- discipline, multi-equation solvers, GUI, tightly coupled configurable 3D field solvers for FVM, FEM and BEM and a 3D visualization/animation tool. The flow/heat transfer/calorics/chemistry equations are solved with unstructured adaptive FVM solver, stress/deformation are computed with a FEM STRESS solver and a FAST BEM solver is used to solve linear heat transfer, electro/magnetostatics and elastostatics equations on adaptive polygonal surface grids. Tight multidisciplinary coupling and automatic interoperability between the tools was achieved by designing a comprehensive database structure and APIs for complete model definition. The virtual model definition is implemented in data transfer facility, a publicly available tool described in this paper. The paper presents overall description of the software architecture and MEMS design flow in ACE + MEMS. It describes current status, ongoing effort and future plans for the software. The paper also discusses new concepts of mixed-level and mixed- dimensionality capability in which 1D microfluidic networks are simulated concurrently with 3D high-fidelity models of discrete components.

Proceedings of the Ninth Annual Software Engineering Workshop

NASA Technical Reports Server (NTRS)

1984-01-01

Experiences in measurement, utilization, and evaluation of software methodologies, models, and tools are discussed. NASA's involvement in ever larger and more complex systems, like the space station project, provides a motive for the support of software engineering research and the exchange of ideas in such forums. The topics of current SEL research are software error studies, experiments with software development, and software tools.

FMT (Flight Software Memory Tracker) For Cassini Spacecraft-Software Engineering Using JAVA

NASA Technical Reports Server (NTRS)

Kan, Edwin P.; Uffelman, Hal; Wax, Allan H.

1997-01-01

The software engineering design of the Flight Software Memory Tracker (FMT) Tool is discussed in this paper. FMT is a ground analysis software set, consisting of utilities and procedures, designed to track the flight software, i.e., images of memory load and updatable parameters of the computers on-board Cassini spacecraft. FMT is implemented in Java.

Requirements: Towards an understanding on why software projects fail

NASA Astrophysics Data System (ADS)

Hussain, Azham; Mkpojiogu, Emmanuel O. C.

2016-08-01

Requirement engineering is at the foundation of every successful software project. There are many reasons for software project failures; however, poorly engineered requirements process contributes immensely to the reason why software projects fail. Software project failure is usually costly and risky and could also be life threatening. Projects that undermine requirements engineering suffer or are likely to suffer from failures, challenges and other attending risks. The cost of project failures and overruns when estimated is very huge. Furthermore, software project failures or overruns pose a challenge in today's competitive market environment. It affects the company's image, goodwill, and revenue drive and decreases the perceived satisfaction of customers and clients. In this paper, requirements engineering was discussed. Its role in software projects success was elaborated. The place of software requirements process in relation to software project failure was explored and examined. Also, project success and failure factors were also discussed with emphasis placed on requirements factors as they play a major role in software projects' challenges, successes and failures. The paper relied on secondary data and empirical statistics to explore and examine factors responsible for the successes, challenges and failures of software projects in large, medium and small scaled software companies.

Sandia National Laboratories Advanced Simulation and Computing (ASC) software quality plan. Part 1 : ASC software quality engineering practices version 1.0.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Minana, Molly A.; Sturtevant, Judith E.; Heaphy, Robert

2005-01-01

The purpose of the Sandia National Laboratories (SNL) Advanced Simulation and Computing (ASC) Software Quality Plan is to clearly identify the practices that are the basis for continually improving the quality of ASC software products. Quality is defined in DOE/AL Quality Criteria (QC-1) as conformance to customer requirements and expectations. This quality plan defines the ASC program software quality practices and provides mappings of these practices to the SNL Corporate Process Requirements (CPR 1.3.2 and CPR 1.3.6) and the Department of Energy (DOE) document, ASCI Software Quality Engineering: Goals, Principles, and Guidelines (GP&G). This quality plan identifies ASC management andmore » software project teams' responsibilities for cost-effective software engineering quality practices. The SNL ASC Software Quality Plan establishes the signatories commitment to improving software products by applying cost-effective software engineering quality practices. This document explains the project teams opportunities for tailoring and implementing the practices; enumerates the practices that compose the development of SNL ASC's software products; and includes a sample assessment checklist that was developed based upon the practices in this document.« less

Proceedings of the 14th Annual Software Engineering Workshop

NASA Technical Reports Server (NTRS)

1989-01-01

Several software related topics are presented. Topics covered include studies and experiment at the Software Engineering Laboratory at the Goddard Space Flight Center, predicting project success from the Software Project Management Process, software environments, testing in a reuse environment, domain directed reuse, and classification tree analysis using the Amadeus measurement and empirical analysis.

Software Process Improvement through the Removal of Project-Level Knowledge Flow Obstacles: The Perceptions of Software Engineers

ERIC Educational Resources Information Center

Mitchell, Susan Marie

2012-01-01

Uncontrollable costs, schedule overruns, and poor end product quality continue to plague the software engineering field. Innovations formulated with the expectation to minimize or eliminate cost, schedule, and quality problems have generally fallen into one of three categories: programming paradigms, software tools, and software process…

RICIS Software Engineering 90 Symposium: Aerospace Applications and Research Directions Proceedings Appendices

NASA Technical Reports Server (NTRS)

1990-01-01

Papers presented at RICIS Software Engineering Symposium are compiled. The following subject areas are covered: flight critical software; management of real-time Ada; software reuse; megaprogramming software; Ada net; POSIX and Ada integration in the Space Station Freedom Program; and assessment of formal methods for trustworthy computer systems.

Technology transfer in software engineering

NASA Technical Reports Server (NTRS)

Bishop, Peter C.

1989-01-01

The University of Houston-Clear Lake is the prime contractor for the AdaNET Research Project under the direction of NASA Johnson Space Center. AdaNET was established to promote the principles of software engineering to the software development industry. AdaNET will contain not only environments and tools, but also concepts, principles, models, standards, guidelines and practices. Initially, AdaNET will serve clients from the U.S. government and private industry who are working in software development. It will seek new clients from those who have not yet adopted the principles and practices of software engineering. Some of the goals of AdaNET are to become known as an objective, authoritative source of new software engineering information and parts, to provide easy access to information and parts, and to keep abreast of innovations in the field.

Effective Software Engineering Leadership for Development Programs

ERIC Educational Resources Information Center

Cagle West, Marsha

2010-01-01

Software is a critical component of systems ranging from simple consumer appliances to complex health, nuclear, and flight control systems. The development of quality, reliable, and effective software solutions requires the incorporation of effective software engineering processes and leadership. Processes, approaches, and methodologies for…

Development of a comprehensive software engineering environment

NASA Technical Reports Server (NTRS)

Hartrum, Thomas C.; Lamont, Gary B.

1987-01-01

The generation of a set of tools for software lifecycle is a recurring theme in the software engineering literature. The development of such tools and their integration into a software development environment is a difficult task because of the magnitude (number of variables) and the complexity (combinatorics) of the software lifecycle process. An initial development of a global approach was initiated in 1982 as the Software Development Workbench (SDW). Continuing efforts focus on tool development, tool integration, human interfacing, data dictionaries, and testing algorithms. Current efforts are emphasizing natural language interfaces, expert system software development associates and distributed environments with Ada as the target language. The current implementation of the SDW is on a VAX-11/780. Other software development tools are being networked through engineering workstations.

Software reengineering

NASA Technical Reports Server (NTRS)

Fridge, Ernest M., III

1991-01-01

Today's software systems generally use obsolete technology, are not integrated properly with other software systems, and are difficult and costly to maintain. The discipline of reverse engineering is becoming prominent as organizations try to move their systems up to more modern and maintainable technology in a cost effective manner. JSC created a significant set of tools to develop and maintain FORTRAN and C code during development of the Space Shuttle. This tool set forms the basis for an integrated environment to re-engineer existing code into modern software engineering structures which are then easier and less costly to maintain and which allow a fairly straightforward translation into other target languages. The environment will support these structures and practices even in areas where the language definition and compilers do not enforce good software engineering. The knowledge and data captured using the reverse engineering tools is passed to standard forward engineering tools to redesign or perform major upgrades to software systems in a much more cost effective manner than using older technologies. A beta vision of the environment was released in Mar. 1991. The commercial potential for such re-engineering tools is very great. CASE TRENDS magazine reported it to be the primary concern of over four hundred of the top MIS executives.

A Recommended Framework for the Network-Centric Acquisition Process

DTIC Science & Technology

2009-09-01

ISO /IEC 12207 , Systems and Software Engineering-Software Life-Cycle Processes  ANSI/EIA 632, Processes for Engineering a System. There are...engineering [46]. Some of the process models presented in the DAG are:  ISO /IEC 15288, Systems and Software Engineering-System Life-Cycle Processes...e.g., ISO , IA, Security, etc.). Vetting developers helps ensure that they are using industry best industry practices and maximize the IA compliance

Software Engineering Education Directory. Software Engineering Curriculum Project

DTIC Science & Technology

1991-05-01

1986 with a questionnaire mailed to schools selected from Peterson’s Graduate Programs in Engineering and Applied Sciences 1986. We contacted schools...the publi- cation more complete. To discuss any issues related to this report, please contact: Education Program Software Engineering Institute...considered to be required course reading. How to Use This Section This portion of the directory is organized by state (in the U.S.), province (in

The Impact of Software on Associate Degree Programs in Electronic Engineering Technology.

ERIC Educational Resources Information Center

Hata, David M.

1986-01-01

Assesses the range and extent of computer assisted instruction software available in electronic engineering technology education. Examines the need for software skills in four areas: (1) high-level languages; (2) assembly language; (3) computer-aided engineering; and (4) computer-aided instruction. Outlines strategies for the future in three…

Software engineering

NASA Technical Reports Server (NTRS)

Fridge, Ernest M., III; Hiott, Jim; Golej, Jim; Plumb, Allan

1993-01-01

Today's software systems generally use obsolete technology, are not integrated properly with other software systems, and are difficult and costly to maintain. The discipline of reverse engineering is becoming prominent as organizations try to move their systems up to more modern and maintainable technology in a cost effective manner. The Johnson Space Center (JSC) created a significant set of tools to develop and maintain FORTRAN and C code during development of the space shuttle. This tool set forms the basis for an integrated environment to reengineer existing code into modern software engineering structures which are then easier and less costly to maintain and which allow a fairly straightforward translation into other target languages. The environment will support these structures and practices even in areas where the language definition and compilers do not enforce good software engineering. The knowledge and data captured using the reverse engineering tools is passed to standard forward engineering tools to redesign or perform major upgrades to software systems in a much more cost effective manner than using older technologies. The latest release of the environment was in Feb. 1992.

The Personal Software Process (PSPSM): An Empirical Study of the Impact of PSP on Individual Engineers.

DTIC Science & Technology

1997-12-01

Watts Humphrey and is described in his book A Discipline for Software Engineering [ Humphrey 95]. Its intended use is to guide the planning and...Pat; Humphrey , Watts S .; Khajenoori, Soheil; Macke, Susan; & Matvya, Annette. "Introducing the Personal Software Process: Three Industry Case... Humphrey 95] Humphrey , Watts S . A Discipline for Software Engineering. Reading, Ma.: Addison-Wesley, 1995. [Mauchly 40] Mauchly, J.W. "Significance

Large-scale visualization projects for teaching software engineering.

PubMed

Müller, Christoph; Reina, Guido; Burch, Michael; Weiskopf, Daniel

2012-01-01

The University of Stuttgart's software engineering major complements the traditional computer science major with more practice-oriented education. Two-semester software projects in various application areas offered by the university's different computer science institutes are a successful building block in the curriculum. With this realistic, complex project setting, students experience the practice of software engineering, including software development processes, technologies, and soft skills. In particular, visualization-based projects are popular with students. Such projects offer them the opportunity to gain profound knowledge that would hardly be possible with only regular lectures and homework assignments.

48 CFR 227.7206 - Contracts for architect-engineer services.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Rights in Computer Software and Computer Software Documentation 227.7206 Contracts for architect-engineer services. Follow 227.7107 when contracting for architect-engineer services. ...-engineer services. 227.7206 Section 227.7206 Federal Acquisition Regulations System DEFENSE ACQUISITION...

48 CFR 227.7206 - Contracts for architect-engineer services.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Rights in Computer Software and Computer Software Documentation 227.7206 Contracts for architect-engineer services. Follow 227.7107 when contracting for architect-engineer services. ...-engineer services. 227.7206 Section 227.7206 Federal Acquisition Regulations System DEFENSE ACQUISITION...

48 CFR 227.7206 - Contracts for architect-engineer services.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Rights in Computer Software and Computer Software Documentation 227.7206 Contracts for architect-engineer services. Follow 227.7107 when contracting for architect-engineer services. ...-engineer services. 227.7206 Section 227.7206 Federal Acquisition Regulations System DEFENSE ACQUISITION...

48 CFR 227.7206 - Contracts for architect-engineer services.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Rights in Computer Software and Computer Software Documentation 227.7206 Contracts for architect-engineer services. Follow 227.7107 when contracting for architect-engineer services. ...-engineer services. 227.7206 Section 227.7206 Federal Acquisition Regulations System DEFENSE ACQUISITION...

48 CFR 227.7206 - Contracts for architect-engineer services.

Code of Federal Regulations, 2010 CFR

2010-10-01

...-engineer services. 227.7206 Section 227.7206 Federal Acquisition Regulations System DEFENSE ACQUISITION... Rights in Computer Software and Computer Software Documentation 227.7206 Contracts for architect-engineer services. Follow 227.7107 when contracting for architect-engineer services. ...

A Novel Coupling Pattern in Computational Science and Engineering Software

EPA Science Inventory

Computational science and engineering (CSE) software is written by experts of certain area(s). Due to the specialization, existing CSE software may need to integrate other CSE software systems developed by different groups of experts. The coupling problem is one of the challenges...

A Novel Coupling Pattern in Computational Science and Engineering Software

EPA Science Inventory

Computational science and engineering (CSE) software is written by experts of certain area(s). Due to the specialization,existing CSE software may need to integrate other CSE software systems developed by different groups of experts. Thecoupling problem is one of the challenges f...

Modeling a distributed environment for a petroleum reservoir engineering application with software product line

NASA Astrophysics Data System (ADS)

de Faria Scheidt, Rafael; Vilain, Patrícia; Dantas, M. A. R.

2014-10-01

Petroleum reservoir engineering is a complex and interesting field that requires large amount of computational facilities to achieve successful results. Usually, software environments for this field are developed without taking care out of possible interactions and extensibilities required by reservoir engineers. In this paper, we present a research work which it is characterized by the design and implementation based on a software product line model for a real distributed reservoir engineering environment. Experimental results indicate successfully the utilization of this approach for the design of distributed software architecture. In addition, all components from the proposal provided greater visibility of the organization and processes for the reservoir engineers.

Software IV and V Research Priorities and Applied Program Accomplishments Within NASA

NASA Technical Reports Server (NTRS)

Blazy, Louis J.

2000-01-01

The mission of this research is to be world-class creators and facilitators of innovative, intelligent, high performance, reliable information technologies that enable NASA missions to (1) increase software safety and quality through error avoidance, early detection and resolution of errors, by utilizing and applying empirically based software engineering best practices; (2) ensure customer software risks are identified and/or that requirements are met and/or exceeded; (3) research, develop, apply, verify, and publish software technologies for competitive advantage and the advancement of science; and (4) facilitate the transfer of science and engineering data, methods, and practices to NASA, educational institutions, state agencies, and commercial organizations. The goals are to become a national Center Of Excellence (COE) in software and system independent verification and validation, and to become an international leading force in the field of software engineering for improving the safety, quality, reliability, and cost performance of software systems. This project addresses the following problems: Ensure safety of NASA missions, ensure requirements are met, minimize programmatic and technological risks of software development and operations, improve software quality, reduce costs and time to delivery, and improve the science of software engineering

Toward Eco Product Development with Qualitative and CAE Design Process - Case Study of Flame Guiding Module

NASA Astrophysics Data System (ADS)

Chen, W. L.; Chao, F. L.

2018-04-01

Sustainable products become increasingly important for company in addressing eco-performance to satisfy global environmental regulations. Case study of flame guiding module reviewed design process and concerns related to the torch design. For enhancing flame height, the torch was embedded with an airflow guidance structure. The design process and design methodologies were investigated as an eco-design case study. Combine qualitative and CAE simulation were proposed to fulfil its main and auxiliary functions including reduction of impact during use. The design guidelines help prevent mistake arrangements, CAE helps understand combustion phenomenon. The flow field simulation enables fine tune of geometric design. Functional test and measurement are carried out to confirm the product features. On Eco-performance, we choose 5 items for evaluation the status of previous and redesign module, namely function need, low impact material, few manufacturing steps, low energy consumption, and safety. The radar diagram indicates that eco-performance of redesign module is better. Life cycle assessment calculated the carbon footprint of the manufacturing and processing stage with Eco-it. By using recycled steel in the flame module, it reduces raw material stage carbon footprint significantly.

Larvicidal Activity against Aedes aegypti and Chemical Characterization of the Inflorescences of Tagetes patula

PubMed Central

Antonelli-Ushirobira, Tânia Mara; Panizzon, Gean; Sereia, Ana Luiza; de Souza, José Roberto Pinto; Zequi, João Antonio Cyrino; Novello, Cláudio Roberto; Lopes, Gisely Cristiny; de Medeiros, Daniela Cristina; Silva, Denise Brentan; Leite-Mello, Eneri Vieira de Souza

2017-01-01

The crude acetone extract (CAE) of defatted inflorescences of Tagetes patula was partitioned into five semipurified fractions: n-hexane (HF), dichloromethane (DF), ethyl acetate (EAF), n-butanol (BF), and aqueous (AQF). BF was fractionated by reversed-phase polyamide column chromatography, obtaining 34 subfractions, which were subjected to HSCCC, where patuletin and patulitrin were isolated. CAE and the fractions BF, EAF, DF, and AQF were analyzed by LC-DAD-MS, and patuletin and patulitrin were determined as the major substances in EAF and BF, respectively. BF was also analyzed by HPLC and capillary electrophoresis (CE), and patulitrin was again determined to be the main substance in this fraction. CAE and the semipurified fractions (750, 500, 300, 100, and 50 mg/L) were assayed for larvicidal activity against Aedes aegypti, with mortality rate expressed as percentage. All fractions except AQF showed insecticidal activity after 24 h exposure of larvae to the highest concentration. However, EAF showed the highest activity with more than 50% reduction in larval population at 50 mg/L. The insecticidal activity observed with EAF might have been due to the higher concentration of patuletin present in this fraction. PMID:29362590

Core heat convection in NSTX-U via modification of electron orbits by high frequency Alfvén eigenmodes

NASA Astrophysics Data System (ADS)

Crocker, N. A.; Tritz, K.; White, R. B.; Fredrickson, E. D.; Gorelenkov, N. N.; NSTX-U Team

2015-11-01

New simulation results demonstrate that high frequency compressional (CAE) and global (GAE) Alfvén eigenmodes cause radial convection of electrons, with implications for particle and energy confinement, as well as electric field formation in NSTX-U. Simulations of electron orbits in the presence of multiple experimentally determined CAEs and GAEs, using the gyro-center code ORBIT, have revealed substantial convective transport, in addition to the expected diffusion via orbit stochastization. These results advance understanding of anomalous core energy transport expected in high performance, beam-heated NSTX-U plasmas. The simulations make use of experimentally determined density perturbation (δn) amplitudes and mode structures obtained by inverting measurements from 16 a channel reflectometer array using a synthetic diagnostic. Combined with experimentally determined mode polarizations (i.e. CAE or GAE), the δn are used to estimate the ExB displacements for use in ORBIT. Preliminary comparison of the simulation results with transport modeling by TRANSP indicate that the convection is currently underestimated. Supported by US DOE Contracts DE-SC0011810, DE-FG02-99ER54527 & DE-AC02-09CH11466.

Intelligent Image Based Computer Aided Education (IICAE)

NASA Astrophysics Data System (ADS)

David, Amos A.; Thiery, Odile; Crehange, Marion

1989-03-01

Artificial Intelligence (AI) has found its way into Computer Aided Education (CAE), and there are several systems constructed to put in evidence its interesting advantages. We believe that images (graphic or real) play an important role in learning. However, the use of images, outside their use as illustration, makes it necessary to have applications such as AI. We shall develop the application of AI in an image based CAE and briefly present the system under construction to put in evidence our concept. We shall also elaborate a methodology for constructing such a system. Futhermore we shall briefly present the pedagogical and psychological activities in a learning process. Under the pedagogical and psychological aspect of learning, we shall develop areas such as the importance of image in learning both as pedagogical objects as well as means for obtaining psychological information about the learner. We shall develop the learner's model, its use, what to build into it and how. Under the application of AI in an image based CAE, we shall develop the importance of AI in exploiting the knowledge base in the learning environment and its application as a means of implementing pedagogical strategies.

Implementing large projects in software engineering courses

NASA Astrophysics Data System (ADS)

Coppit, David

2006-03-01

In software engineering education, large projects are widely recognized as a useful way of exposing students to the real-world difficulties of team software development. But large projects are difficult to put into practice. First, educators rarely have additional time to manage software projects. Second, classrooms have inherent limitations that threaten the realism of large projects. Third, quantitative evaluation of individuals who work in groups is notoriously difficult. As a result, many software engineering courses compromise the project experience by reducing the team sizes, project scope, and risk. In this paper, we present an approach to teaching a one-semester software engineering course in which 20 to 30 students work together to construct a moderately sized (15KLOC) software system. The approach combines carefully coordinated lectures and homeworks, a hierarchical project management structure, modern communication technologies, and a web-based project tracking and individual assessment system. Our approach provides a more realistic project experience for the students, without incurring significant additional overhead for the instructor. We present our experiences using the approach the last 2 years for the software engineering course at The College of William and Mary. Although the approach has some weaknesses, we believe that they are strongly outweighed by the pedagogical benefits.

A Role-Playing Game for a Software Engineering Lab: Developing a Product Line

ERIC Educational Resources Information Center

Zuppiroli, Sara; Ciancarini, Paolo; Gabbrielli, Maurizio

2012-01-01

Software product line development refers to software engineering practices and techniques for creating families of similar software systems from a basic set of reusable components, called shared assets. Teaching how to deal with software product lines in a university lab course is a challenging task, because there are several practical issues that…

On the Prospects and Concerns of Integrating Open Source Software Environment in Software Engineering Education

ERIC Educational Resources Information Center

Kamthan, Pankaj

2007-01-01

Open Source Software (OSS) has introduced a new dimension in software community. As the development and use of OSS becomes prominent, the question of its integration in education arises. In this paper, the following practices fundamental to projects and processes in software engineering are examined from an OSS perspective: project management;…

Ten recommendations for software engineering in research.

PubMed

Hastings, Janna; Haug, Kenneth; Steinbeck, Christoph

2014-01-01

Research in the context of data-driven science requires a backbone of well-written software, but scientific researchers are typically not trained at length in software engineering, the principles for creating better software products. To address this gap, in particular for young researchers new to programming, we give ten recommendations to ensure the usability, sustainability and practicality of research software.

Model Driven Engineering

NASA Astrophysics Data System (ADS)

Gaševic, Dragan; Djuric, Dragan; Devedžic, Vladan

A relevant initiative from the software engineering community called Model Driven Engineering (MDE) is being developed in parallel with the Semantic Web (Mellor et al. 2003a). The MDE approach to software development suggests that one should first develop a model of the system under study, which is then transformed into the real thing (i.e., an executable software entity). The most important research initiative in this area is the Model Driven Architecture (MDA), which is Model Driven Architecture being developed under the umbrella of the Object Management Group (OMG). This chapter describes the basic concepts of this software engineering effort.

Architecture independent environment for developing engineering software on MIMD computers

NASA Technical Reports Server (NTRS)

Valimohamed, Karim A.; Lopez, L. A.

1990-01-01

Engineers are constantly faced with solving problems of increasing complexity and detail. Multiple Instruction stream Multiple Data stream (MIMD) computers have been developed to overcome the performance limitations of serial computers. The hardware architectures of MIMD computers vary considerably and are much more sophisticated than serial computers. Developing large scale software for a variety of MIMD computers is difficult and expensive. There is a need to provide tools that facilitate programming these machines. First, the issues that must be considered to develop those tools are examined. The two main areas of concern were architecture independence and data management. Architecture independent software facilitates software portability and improves the longevity and utility of the software product. It provides some form of insurance for the investment of time and effort that goes into developing the software. The management of data is a crucial aspect of solving large engineering problems. It must be considered in light of the new hardware organizations that are available. Second, the functional design and implementation of a software environment that facilitates developing architecture independent software for large engineering applications are described. The topics of discussion include: a description of the model that supports the development of architecture independent software; identifying and exploiting concurrency within the application program; data coherence; engineering data base and memory management.

NASA Software Documentation Standard

NASA Technical Reports Server (NTRS)

1991-01-01

The NASA Software Documentation Standard (hereinafter referred to as "Standard") is designed to support the documentation of all software developed for NASA; its goal is to provide a framework and model for recording the essential information needed throughout the development life cycle and maintenance of a software system. The NASA Software Documentation Standard can be applied to the documentation of all NASA software. The Standard is limited to documentation format and content requirements. It does not mandate specific management, engineering, or assurance standards or techniques. This Standard defines the format and content of documentation for software acquisition, development, and sustaining engineering. Format requirements address where information shall be recorded and content requirements address what information shall be recorded. This Standard provides a framework to allow consistency of documentation across NASA and visibility into the completeness of project documentation. The basic framework consists of four major sections (or volumes). The Management Plan contains all planning and business aspects of a software project, including engineering and assurance planning. The Product Specification contains all technical engineering information, including software requirements and design. The Assurance and Test Procedures contains all technical assurance information, including Test, Quality Assurance (QA), and Verification and Validation (V&V). The Management, Engineering, and Assurance Reports is the library and/or listing of all project reports.

Training, Quality Assurance Factors, and Tools Investigation: a Work Report and Suggestions on Software Quality Assurance

NASA Technical Reports Server (NTRS)

Lee, Pen-Nan

1991-01-01

Previously, several research tasks have been conducted, some observations were obtained, and several possible suggestions have been contemplated involving software quality assurance engineering at NASA Johnson. These research tasks are briefly described. Also, a brief discussion is given on the role of software quality assurance in software engineering along with some observations and suggestions. A brief discussion on a training program for software quality assurance engineers is provided. A list of assurance factors as well as quality factors are also included. Finally, a process model which can be used for searching and collecting software quality assurance tools is presented.

An automated design and fabrication pipeline for improving the strength of 3D printed artifacts under tensile loading

NASA Astrophysics Data System (ADS)

Al, Can Mert; Yaman, Ulas

2018-05-01

In the scope of this study, an alternative automated method to the conventional design and fabrication pipeline of 3D printers is developed by using an integrated CAD/CAE/CAM approach. It increases the load carrying capacity of the parts by constructing heterogeneous infill structures. Traditional CAM software of Additive Manufacturing machinery starts with a design model in STL file format which only includes data about the outer boundary in the triangular mesh form. Depending on the given infill percentage, the algorithm running behind constructs the interior of the artifact by using homogeneous infill structures. As opposed to the current CAM software, the proposed method provides a way to construct heterogeneous infill structures with respect to the Von Misses stress field results obtained from a finite element analysis. Throughout the work, Rhinoceros3D is used for the design of the parts along with Grasshopper3D, an algorithmic design tool for Rhinoceros3D. In addition, finite element analyses are performed using Karamba3D, a plug-in for Grasshopper3D. According to the results of the tensile tests, the method offers an improvement of load carrying capacity about 50% compared to traditional slicing algorithms of 3D printing.

Computational hemodynamics of an implanted coronary stent based on three-dimensional cine angiography reconstruction.

PubMed

Chen, Mounter C Y; Lu, Po-Chien; Chen, James S Y; Hwang, Ned H C

2005-01-01

Coronary stents are supportive wire meshes that keep narrow coronary arteries patent, reducing the risk of restenosis. Despite the common use of coronary stents, approximately 20-35% of them fail due to restenosis. Flow phenomena adjacent to the stent may contribute to restenosis. Three-dimensional computational fluid dynamics (CFD) and reconstruction based on biplane cine angiography were used to assess coronary geometry and volumetric blood flows. A patient-specific left anterior descending (LAD) artery was reconstructed from single-plane x-ray imaging. With corresponding electrocardiographic signals, images from the same time phase were selected from the angiograms for dynamic three-dimensional reconstruction. The resultant three-dimensional LAD artery at end-diastole was adopted for detailed analysis. Both the geometries and flow fields, based on a computational model from CAE software (ANSYS and CATIA) and full three-dimensional Navier-Stroke equations in the CFD-ACE+ software, respectively, changed dramatically after stent placement. Flow fields showed a complex three-dimensional spiral motion due to arterial tortuosity. The corresponding wall shear stresses, pressure gradient, and flow field all varied significantly after stent placement. Combined angiography and CFD techniques allow more detailed investigation of flow patterns in various segments. The implanted stent(s) may be quantitatively studied from the proposed hemodynamic modeling approach.

EngineSim: Turbojet Engine Simulator Adapted for High School Classroom Use

NASA Technical Reports Server (NTRS)

Petersen, Ruth A.

2001-01-01

EngineSim is an interactive educational computer program that allows users to explore the effect of engine operation on total aircraft performance. The software is supported by a basic propulsion web site called the Beginner's Guide to Propulsion, which includes educator-created, web-based activities for the classroom use of EngineSim. In addition, educators can schedule videoconferencing workshops in which EngineSim's creator demonstrates the software and discusses its use in the educational setting. This software is a product of NASA Glenn Research Center's Learning Technologies Project, an educational outreach initiative within the High Performance Computing and Communications Program.

Evaluating software development characteristics: Assessment of software measures in the Software Engineering Laboratory. [reliability engineering

NASA Technical Reports Server (NTRS)

Basili, V. R.

1981-01-01

Work on metrics is discussed. Factors that affect software quality are reviewed. Metrics is discussed in terms of criteria achievements, reliability, and fault tolerance. Subjective and objective metrics are distinguished. Product/process and cost/quality metrics are characterized and discussed.

Computer-aided analysis of cutting processes for brittle materials

NASA Astrophysics Data System (ADS)

Ogorodnikov, A. I.; Tikhonov, I. N.

2017-12-01

This paper is focused on 3D computer simulation of cutting processes for brittle materials and silicon wafers. Computer-aided analysis of wafer scribing and dicing is carried out with the use of the ANSYS CAE (computer-aided engineering) software, and a parametric model of the processes is created by means of the internal ANSYS APDL programming language. Different types of tool tip geometry are analyzed to obtain internal stresses, such as a four-sided pyramid with an included angle of 120° and a tool inclination angle to the normal axis of 15°. The quality of the workpieces after cutting is studied by optical microscopy to verify the FE (finite-element) model. The disruption of the material structure during scribing occurs near the scratch and propagates into the wafer or over its surface at a short range. The deformation area along the scratch looks like a ragged band, but the stress width is rather low. The theory of cutting brittle semiconductor and optical materials is developed on the basis of the advanced theory of metal turning. The fall of stress intensity along the normal on the way from the tip point to the scribe line can be predicted using the developed theory and with the verified FE model. The crystal quality and dimensions of defects are determined by the mechanics of scratching, which depends on the shape of the diamond tip, the scratching direction, the velocity of the cutting tool and applied force loads. The disunity is a rate-sensitive process, and it depends on the cutting thickness. The application of numerical techniques, such as FE analysis, to cutting problems enhances understanding and promotes the further development of existing machining technologies.

EWB: The Environment WorkBench Version 4.0

NASA Technical Reports Server (NTRS)

1995-01-01

The Environment WorkBench EWB is a desktop integrated analysis tool for studying a spacecraft's interactions with its environment. Over 100 environment and analysis models are integrated into the menu-based tool. EWB, which was developed for and under the guidance of the NASA Lewis Research Center, is built atop the Module Integrator and Rule-based Intelligent Analytic Database (MIRIAD) architecture. This allows every module in EWB to communicate information to other modules in a transparent manner from the user's point of view. It removes the tedious and error-prone steps of entering data by hand from one model to another. EWB runs under UNIX operating systems (SGI and SUN workstations) and under MS Windows (3.x, 95, and NT) operating systems. MIRIAD, the unique software that makes up the core of EWB, provides the flexibility to easily modify old models and incorporate new ones as user needs change. The MIRIAD approach separates the computer assisted engineering (CAE) tool into three distinct units: 1) A modern graphical user interface to present information; 2) A data dictionary interpreter to coordinate analysis; and 3) A database for storing system designs and analysis results. The user interface is externally programmable through ASCII data files, which contain the location and type of information to be displayed on the screen. This approach provides great flexibility in tailoring the look and feel of the code to individual user needs. MIRIADbased applications, such as EWB, have utilities for viewing tabulated parametric study data, XY line plots, contour plots, and three-dimensional plots of contour data and system geometries. In addition, a Monte Carlo facility is provided to allow statistical assessments (including uncertainties) in models or data.

Conditions of Fissuring in a Pumped-Faulted Aquifer System

NASA Astrophysics Data System (ADS)

Hernandez-Marin, M.; Burbey, T. J.

2007-12-01

Earth fissuring associated with subsidence from groundwater pumping is problematic in many arid-zone heavily pumped basins such as Las Vegas Valley. Long-term pumping at rates considerably greater than the natural recharge rate has stressed the heterogeneous aquifer system resulting in a complex stress-strain regime. A rigorous artificial recharge program coupled with increased surface-water importation has allowed water levels to appreciably recover, which has led to surface rebound in some localities. Nonetheless, new fissures continue to appear, particularly near basin-fill faults that behave as barriers to subsidence bowls. The purpose of this research is to develop a series of computational models to better understand the influence that structure (faults), pumping, and hydrostratigraphy has in the generation and propagation of fissures. The hydrostratigraphy of Las Vegas Valley consists of aquifers, aquitards and a relatively dry vadoze zone that may be as thick as 100m in much of the valley. Quaternary faults are typically depicted as scarps resulting from pre- pumping extensional tectonic events and are probably not responsible for the observed strain. The models developed to simulate the stress-strain and deformation processes in a faulted pumped aquifer-aquitard system of Las Vegas use the ABAQUS CAE (Complete ABAQUS Environment) software system. ABAQUS is a sophisticated engineering industry finite-element modeling package capable of simulating the complex fault- fissure system described here. A brittle failure criteria based on the tensile strength of the materials and the acting stresses (from previous models) are being used to understand how and where fissures are likely to form. , Hypothetical simulations include the role that faults and the vadose zone may play in fissure formation

Are Earth System model software engineering practices fit for purpose? A case study.

NASA Astrophysics Data System (ADS)

Easterbrook, S. M.; Johns, T. C.

2009-04-01

We present some analysis and conclusions from a case study of the culture and practices of scientists at the Met Office and Hadley Centre working on the development of software for climate and Earth System models using the MetUM infrastructure. The study examined how scientists think about software correctness, prioritize their requirements in making changes, and develop a shared understanding of the resulting models. We conclude that highly customized techniques driven strongly by scientific research goals have evolved for verification and validation of such models. In a formal software engineering context these represents costly, but invaluable, software integration tests with considerable benefits. The software engineering practices seen also exhibit recognisable features of both agile and open source software development projects - self-organisation of teams consistent with a meritocracy rather than top-down organisation, extensive use of informal communication channels, and software developers who are generally also users and science domain experts. We draw some general conclusions on whether these practices work well, and what new software engineering challenges may lie ahead as Earth System models become ever more complex and petascale computing becomes the norm.

Software engineering and Ada in design

NASA Technical Reports Server (NTRS)

Oneill, Don

1986-01-01

Modern software engineering promises significant reductions in software costs and improvements in software quality. The Ada language is the focus for these software methodology and tool improvements. The IBM FSD approach, including the software engineering practices that guide the systematic design and development of software products and the management of the software process are examined. The revised Ada design language adaptation is revealed. This four level design methodology is detailed including the purpose of each level, the management strategy that integrates the software design activity with the program milestones, and the technical strategy that maps the Ada constructs to each level of design. A complete description of each design level is provided along with specific design language recording guidelines for each level. Finally, some testimony is offered on education, tools, architecture, and metrics resulting from project use of the four level Ada design language adaptation.

CrossTalk: The Journal of Defense Software Engineering. Volume 20, Number 6, June 2007

DTIC Science & Technology

2007-06-01

California. He has co-authored the book Software Cost Estimation With COCOMO II with Barry Boehm and others. Clark helped define the COCOMO II model...Software Engineering at the University of Southern California. She worked with Barry Boehm and Chris Abts to develop and calibrate a cost-estimation...2003/02/ schorsch.html>. 2. See “Software Engineering, A Practitioners Approach” by Roger Pressman for a good description of coupling, cohesion

Agile Software Teams: How They Engage with Systems Engineering on DoD Acquisition Programs

DTIC Science & Technology

2014-07-01

under Contract No. FA8721-05-C-0003 with Carnegie Mellon University for the operation of the Software Engineer- ing Institute, a federally funded...issues that would preclude or limit the use of Agile methods within the DoD” [Broadus 2013]. As operational tempos increase and programs fight to...environment in which it operates . This makes software different from other disciplines that have toleranc- es, generally resulting in software engineering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peck, T; Sparkman, D; Storch, N

''The LLNL Site-Specific Advanced Simulation and Computing (ASCI) Software Quality Engineering Recommended Practices VI.I'' document describes a set of recommended software quality engineering (SQE) practices for ASCI code projects at Lawrence Livermore National Laboratory (LLNL). In this context, SQE is defined as the process of building quality into software products by applying the appropriate guiding principles and management practices. Continual code improvement and ongoing process improvement are expected benefits. Certain practices are recommended, although projects may select the specific activities they wish to improve, and the appropriate time lines for such actions. Additionally, projects can rely on the guidance ofmore » this document when generating ASCI Verification and Validation (VSrV) deliverables. ASCI program managers will gather information about their software engineering practices and improvement. This information can be shared to leverage the best SQE practices among development organizations. It will further be used to ensure the currency and vitality of the recommended practices. This Overview is intended to provide basic information to the LLNL ASCI software management and development staff from the ''LLNL Site-Specific ASCI Software Quality Engineering Recommended Practices VI.I'' document. Additionally the Overview provides steps to using the ''LLNL Site-Specific ASCI Software Quality Engineering Recommended Practices VI.I'' document. For definitions of terminology and acronyms, refer to the Glossary and Acronyms sections in the ''LLNL Site-Specific ASCI Software Quality Engineering Recommended Practices VI.I''.« less

The Effective Use of Professional Software in an Undergraduate Mining Engineering Curriculum

ERIC Educational Resources Information Center

Kecojevic, Vladislav; Bise, Christopher; Haight, Joel

2005-01-01

The use of professional software is an integral part of a student's education in the mining engineering curriculum at The Pennsylvania State University. Even though mining engineering represents a limited market across U.S. educational institutions, the goal still exists for using this type of software to enrich the learning environment with…

The Curiosity Mars Rover's Fault Protection Engine

NASA Technical Reports Server (NTRS)

Benowitz, Ed

2014-01-01

The Curiosity Rover, currently operating on Mars, contains flight software onboard to autonomously handle aspects of system fault protection. Over 1000 monitors and 39 responses are present in the flight software. Orchestrating these behaviors is the flight software's fault protection engine. In this paper, we discuss the engine's design, responsibilities, and present some lessons learned for future missions.

A Guideline of Using Case Method in Software Engineering Courses

ERIC Educational Resources Information Center

Zainal, Dzulaiha Aryanee Putri; Razali, Rozilawati; Shukur, Zarina

2014-01-01

Software Engineering (SE) education has been reported to fall short in producing high quality software engineers. In seeking alternative solutions, Case Method (CM) is regarded as having potential to solve the issue. CM is a teaching and learning (T&L) method that has been found to be effective in Social Science education. In principle,…

Success Factors for Using Case Method in Teaching and Learning Software Engineering

ERIC Educational Resources Information Center

Razali, Rozilawati; Zainal, Dzulaiha Aryanee Putri

2013-01-01

The Case Method (CM) has long been used effectively in Social Science education. Its potential use in Applied Science such as Software Engineering (SE) however has yet to be further explored. SE is an engineering discipline that concerns the principles, methods and tools used throughout the software development lifecycle. In CM, subjects are…

Network Profiling Using Flow

DTIC Science & Technology

2012-08-01

Software Engineering Institute, a federally funded research and development center. Any opinions, findings and conclusions or recommendations...CARNEGIE MELLON UNIVERSITY AND SOFTWARE ENGINEERING INSTITUTE MATERIAL IS FURNISHED ON AN “AS-IS” BASIS. CARNEGIE MELLON UNIVERSITY MAKES NO WARRANTIES OF...required for any other external and/or commercial use. Requests for permission should be directed to the Software Engineering Institute at permission

IPAD project overview

NASA Technical Reports Server (NTRS)

Fulton, R. E.

1980-01-01

To respond to national needs for improved productivity in engineering design and manufacturing, a NASA supported joint industry/government project is underway denoted Integrated Programs for Aerospace-Vehicle Design (IPAD). The objective is to improve engineering productivity through better use of computer technology. It focuses on development of technology and associated software for integrated company-wide management of engineering information. The project has been underway since 1976 under the guidance of an Industry Technical Advisory Board (ITAB) composed of representatives of major engineering and computer companies and in close collaboration with the Air Force Integrated Computer-Aided Manufacturing (ICAM) program. Results to date on the IPAD project include an in-depth documentation of a representative design process for a large engineering project, the definition and design of computer-aided design software needed to support that process, and the release of prototype software to integrate selected design functions. Ongoing work concentrates on development of prototype software to manage engineering information, and initial software is nearing release.

A Discussion of the Software Quality Assurance Role

NASA Technical Reports Server (NTRS)

Kandt, Ronald Kirk

2010-01-01

The basic idea underlying this paper is that the conventional understanding of the role of a Software Quality Assurance (SQA) engineer is unduly limited. This is because few have asked who the customers of a SQA engineer are. Once you do this, you can better define what tasks a SQA engineer should perform, as well as identify the knowledge and skills that such a person should have. The consequence of doing this is that a SQA engineer can provide greater value to his or her customers. It is the position of this paper that a SQA engineer providing significant value to his or her customers must not only assume the role of an auditor, but also that of a software and systems engineer. This is because software engineers and their managers particularly value contributions that directly impact products and their development. These ideas are summarized as lessons learned, based on my experience at Jet Propulsion Laboratory (JPL).

Testing Scientific Software: A Systematic Literature Review.

PubMed

Kanewala, Upulee; Bieman, James M

2014-10-01

Scientific software plays an important role in critical decision making, for example making weather predictions based on climate models, and computation of evidence for research publications. Recently, scientists have had to retract publications due to errors caused by software faults. Systematic testing can identify such faults in code. This study aims to identify specific challenges, proposed solutions, and unsolved problems faced when testing scientific software. We conducted a systematic literature survey to identify and analyze relevant literature. We identified 62 studies that provided relevant information about testing scientific software. We found that challenges faced when testing scientific software fall into two main categories: (1) testing challenges that occur due to characteristics of scientific software such as oracle problems and (2) testing challenges that occur due to cultural differences between scientists and the software engineering community such as viewing the code and the model that it implements as inseparable entities. In addition, we identified methods to potentially overcome these challenges and their limitations. Finally we describe unsolved challenges and how software engineering researchers and practitioners can help to overcome them. Scientific software presents special challenges for testing. Specifically, cultural differences between scientist developers and software engineers, along with the characteristics of the scientific software make testing more difficult. Existing techniques such as code clone detection can help to improve the testing process. Software engineers should consider special challenges posed by scientific software such as oracle problems when developing testing techniques.

Developing Parametric Models for the Assembly of Machine Fixtures for Virtual Multiaxial CNC Machining Centers

NASA Astrophysics Data System (ADS)

Balaykin, A. V.; Bezsonov, K. A.; Nekhoroshev, M. V.; Shulepov, A. P.

2018-01-01

This paper dwells upon a variance parameterization method. Variance or dimensional parameterization is based on sketching, with various parametric links superimposed on the sketch objects and user-imposed constraints in the form of an equation system that determines the parametric dependencies. This method is fully integrated in a top-down design methodology to enable the creation of multi-variant and flexible fixture assembly models, as all the modeling operations are hierarchically linked in the built tree. In this research the authors consider a parameterization method of machine tooling used for manufacturing parts using multiaxial CNC machining centers in the real manufacturing process. The developed method allows to significantly reduce tooling design time when making changes of a part’s geometric parameters. The method can also reduce time for designing and engineering preproduction, in particular, for development of control programs for CNC equipment and control and measuring machines, automate the release of design and engineering documentation. Variance parameterization helps to optimize construction of parts as well as machine tooling using integrated CAE systems. In the framework of this study, the authors demonstrate a comprehensive approach to parametric modeling of machine tooling in the CAD package used in the real manufacturing process of aircraft engines.

An Investigation of an Open-Source Software Development Environment in a Software Engineering Graduate Course

ERIC Educational Resources Information Center

Ge, Xun; Huang, Kun; Dong, Yifei

2010-01-01

A semester-long ethnography study was carried out to investigate project-based learning in a graduate software engineering course through the implementation of an Open-Source Software Development (OSSD) learning environment, which featured authentic projects, learning community, cognitive apprenticeship, and technology affordances. The study…

Implementing Large Projects in Software Engineering Courses

ERIC Educational Resources Information Center

Coppit, David

2006-01-01

In software engineering education, large projects are widely recognized as a useful way of exposing students to the real-world difficulties of team software development. But large projects are difficult to put into practice. First, educators rarely have additional time to manage software projects. Second, classrooms have inherent limitations that…

Software Development in the Water Sciences: a view from the divide (Invited)

NASA Astrophysics Data System (ADS)

Miles, B.; Band, L. E.

2013-12-01

While training in statistical methods is an important part of many earth scientists' training, these scientists often learn the bulk of their software development skills in an ad hoc, just-in-time manner. Yet to carry out contemporary research scientists are spending more and more time developing software. Here I present perspectives - as an earth sciences graduate student with professional software engineering experience - on the challenges scientists face adopting software engineering practices, with an emphasis on areas of the science software development lifecycle that could benefit most from improved engineering. This work builds on experience gained as part of the NSF-funded Water Science Software Institute (WSSI) conceptualization award (NSF Award # 1216817). Throughout 2013, the WSSI team held a series of software scoping and development sprints with the goals of: (1) adding features to better model green infrastructure within the Regional Hydro-Ecological Simulation System (RHESSys); and (2) infusing test-driven agile software development practices into the processes employed by the RHESSys team. The goal of efforts such as the WSSI is to ensure that investments by current and future scientists in software engineering training will enable transformative science by improving both scientific reproducibility and researcher productivity. Experience with the WSSI indicates: (1) the potential for achieving this goal; and (2) while scientists are willing to adopt some software engineering practices, transformative science will require continued collaboration between domain scientists and cyberinfrastructure experts for the foreseeable future.

Method of transition from 3D model to its ontological representation in aircraft design process

NASA Astrophysics Data System (ADS)

Govorkov, A. S.; Zhilyaev, A. S.; Fokin, I. V.

2018-05-01

This paper proposes the method of transition from a 3D model to its ontological representation and describes its usage in the aircraft design process. The problems of design for manufacturability and design automation are also discussed. The introduced method is to aim to ease the process of data exchange between important aircraft design phases, namely engineering and design control. The method is also intended to increase design speed and 3D model customizability. This requires careful selection of the complex systems (CAD / CAM / CAE / PDM), providing the basis for the integration of design and technological preparation of production and more fully take into account the characteristics of products and processes for their manufacture. It is important to solve this problem, as investment in the automation define the company's competitiveness in the years ahead.

Engineering and Software Engineering

NASA Astrophysics Data System (ADS)

Jackson, Michael

The phrase ‘software engineering' has many meanings. One central meaning is the reliable development of dependable computer-based systems, especially those for critical applications. This is not a solved problem. Failures in software development have played a large part in many fatalities and in huge economic losses. While some of these failures may be attributable to programming errors in the narrowest sense—a program's failure to satisfy a given formal specification—there is good reason to think that most of them have other roots. These roots are located in the problem of software engineering rather than in the problem of program correctness. The famous 1968 conference was motivated by the belief that software development should be based on “the types of theoretical foundations and practical disciplines that are traditional in the established branches of engineering.” Yet after forty years of currency the phrase ‘software engineering' still denotes no more than a vague and largely unfulfilled aspiration. Two major causes of this disappointment are immediately clear. First, too many areas of software development are inadequately specialised, and consequently have not developed the repertoires of normal designs that are the indispensable basis of reliable engineering success. Second, the relationship between structural design and formal analytical techniques for software has rarely been one of fruitful synergy: too often it has defined a boundary between competing dogmas, at which mutual distrust and incomprehension deprive both sides of advantages that should be within their grasp. This paper discusses these causes and their effects. Whether the common practice of software development will eventually satisfy the broad aspiration of 1968 is hard to predict; but an understanding of past failure is surely a prerequisite of future success.

Enhancing requirements engineering for patient registry software systems with evidence-based components.

PubMed

Lindoerfer, Doris; Mansmann, Ulrich

2017-07-01

Patient registries are instrumental for medical research. Often their structures are complex and their implementations use composite software systems to meet the wide spectrum of challenges. Commercial and open-source systems are available for registry implementation, but many research groups develop their own systems. Methodological approaches in the selection of software as well as the construction of proprietary systems are needed. We propose an evidence-based checklist, summarizing essential items for patient registry software systems (CIPROS), to accelerate the requirements engineering process. Requirements engineering activities for software systems follow traditional software requirements elicitation methods, general software requirements specification (SRS) templates, and standards. We performed a multistep procedure to develop a specific evidence-based CIPROS checklist: (1) A systematic literature review to build a comprehensive collection of technical concepts, (2) a qualitative content analysis to define a catalogue of relevant criteria, and (3) a checklist to construct a minimal appraisal standard. CIPROS is based on 64 publications and covers twelve sections with a total of 72 items. CIPROS also defines software requirements. Comparing CIPROS with traditional software requirements elicitation methods, SRS templates and standards show a broad consensus but differences in issues regarding registry-specific aspects. Using an evidence-based approach to requirements engineering for registry software adds aspects to the traditional methods and accelerates the software engineering process for registry software. The method we used to construct CIPROS serves as a potential template for creating evidence-based checklists in other fields. The CIPROS list supports developers in assessing requirements for existing systems and formulating requirements for their own systems, while strengthening the reporting of patient registry software system descriptions. It may be a first step to create standards for patient registry software system assessments. Copyright © 2017 Elsevier Inc. All rights reserved.

Proceedings of the Eighteenth Annual Software Engineering Workshop

NASA Technical Reports Server (NTRS)

1993-01-01

The workshop provided a forum for software practitioners from around the world to exchange information on the measurement, use, and evaluation of software methods, models, and tools. This year, approximately 450 people attended the workshop, which consisted of six sessions on the following topics: the Software Engineering Laboratory, measurement, technology assessment, advanced concepts, process, and software engineering issues in NASA. Three presentations were given in each of the topic areas. The content of those presentations and the research papers detailing the work reported are included in these proceedings. The workshop concluded with a tutorial session on how to start an Experience Factory.

A Brief Study of Software Engineering Professional Continuing Education in DoD Acquisition

DTIC Science & Technology

2010-04-01

Lifecycle Processes (IEEE 12207 ) (810) 37% 61% 2% Guide to the Software Engineering Body of K l d (SWEBOK) (804) 67% 31% 2% now e ge Software...Engineering-Software Measurement Process ( ISO /IEC 15939) (797) 55% 44% 2% Capability Maturity Model Integration (806) 17% 81% 2% Six Sigma Process...Improvement (804) 7% 91% 1% ISO 9000 Quality Management Systems (803) 10% 89% 1% 28 Conclusions Significant problem areas R i tequ remen s Management Very

Proceedings of the Twenty-Third Annual Software Engineering Workshop

NASA Technical Reports Server (NTRS)

1999-01-01

The Twenty-third Annual Software Engineering Workshop (SEW) provided 20 presentations designed to further the goals of the Software Engineering Laboratory (SEL) of the NASA-GSFC. The presentations were selected on their creativity. The sessions which were held on 2-3 of December 1998, centered on the SEL, Experimentation, Inspections, Fault Prediction, Verification and Validation, and Embedded Systems and Safety-Critical Systems.

Reverse Engineering and Software Products Reuse to Teach Collaborative Web Portals: A Case Study with Final-Year Computer Science Students

ERIC Educational Resources Information Center

Medina-Dominguez, Fuensanta; Sanchez-Segura, Maria-Isabel; Mora-Soto, Arturo; Amescua, Antonio

2010-01-01

The development of collaborative Web applications does not follow a software engineering methodology. This is because when university students study Web applications in general, and collaborative Web portals in particular, they are not being trained in the use of software engineering techniques to develop collaborative Web portals. This paper…

A Structured Approach for Reviewing Architecture Documentation

DTIC Science & Technology

2009-12-01

as those found in ISO 12207 [ ISO /IEC 12207 :2008] (for software engineering), ISO 15288 [ ISO /IEC 15288:2008] (for systems engineering), the Rational...Open Distributed Processing - Reference Model: Foundations ( ISO /IEC 10746-2). 1996. [ ISO /IEC 12207 :2008] International Organization for...Standardization & International Electrotechnical Commission. Sys- tems and software engineering – Software life cycle processes ( ISO /IEC 12207 ). 2008. [ ISO

Changes in Transferable Knowledge Resulting from Study in a Graduate Software Engineering Curriculum

ERIC Educational Resources Information Center

Bareiss, Ray; Sedano, Todd; Katz, Edward

2012-01-01

This paper presents the initial results of a study of the evolution of students' knowledge of software engineering from the beginning to the end of a master's degree curriculum in software engineering. Students were presented with a problem involving the initiation of a complex new project at the beginning of the program and again at the end of…

The Relationship between Job Satisfaction and Intent to Turnover among Software Engineers in the Information Technology Industry

ERIC Educational Resources Information Center

Agada, Chuks N.

2013-01-01

The focus of this study was to examine the relationship between job satisfaction and intent to turnover among software engineers in the information technology (IT) industry. The population that was analyzed in this study was software engineers in the IT industry to determine whether there is a relationship between job satisfaction and intent to…

RICIS Software Engineering 90 Symposium: Aerospace Applications and Research Directions Proceedings

NASA Technical Reports Server (NTRS)

1990-01-01

Papers presented at RICIS Software Engineering Symposium are compiled. The following subject areas are covered: synthesis - integrating product and process; Serpent - a user interface management system; prototyping distributed simulation networks; and software reuse.

Software Engineering Laboratory (SEL) data and information policy

NASA Technical Reports Server (NTRS)

Mcgarry, Frank

1991-01-01

The policies and overall procedures that are used in distributing and in making available products of the Software Engineering Laboratory (SEL) are discussed. The products include project data and measures, project source code, reports, and software tools.

Modernizing Systems and Software: How Evolving Trends in Future Trends in Systems and Software Technology Bode Well for Advancing the Precision of Technology

DTIC Science & Technology

2009-04-23

of Code Need for increased functionality will be a forcing function to bring the fields of software and systems engineering... of Software-Intensive Systems is Increasing 3 How Evolving Trends in Systems and Software Technologies Bode Well for Advancing the Precision of ...Engineering in Continued Partnership 4 How Evolving Trends in Systems and Software Technologies Bode Well for Advancing the

Assessing students' performance in software requirements engineering education using scoring rubrics

NASA Astrophysics Data System (ADS)

Mkpojiogu, Emmanuel O. C.; Hussain, Azham

2017-10-01

The study investigates how helpful the use of scoring rubrics is, in the performance assessment of software requirements engineering students and whether its use can lead to students' performance improvement in the development of software requirements artifacts and models. Scoring rubrics were used by two instructors to assess the cognitive performance of a student in the design and development of software requirements artifacts. The study results indicate that the use of scoring rubrics is very helpful in objectively assessing the performance of software requirements or software engineering students. Furthermore, the results revealed that the use of scoring rubrics can also produce a good achievement assessments direction showing whether a student is either improving or not in a repeated or iterative assessment. In a nutshell, its use leads to the performance improvement of students. The results provided some insights for further investigation and will be beneficial to researchers, requirements engineers, system designers, developers and project managers.

Framework Support For Knowledge-Based Software Development

NASA Astrophysics Data System (ADS)

Huseth, Steve

1988-03-01

The advent of personal engineering workstations has brought substantial information processing power to the individual programmer. Advanced tools and environment capabilities supporting the software lifecycle are just beginning to become generally available. However, many of these tools are addressing only part of the software development problem by focusing on rapid construction of self-contained programs by a small group of talented engineers. Additional capabilities are required to support the development of large programming systems where a high degree of coordination and communication is required among large numbers of software engineers, hardware engineers, and managers. A major player in realizing these capabilities is the framework supporting the software development environment. In this paper we discuss our research toward a Knowledge-Based Software Assistant (KBSA) framework. We propose the development of an advanced framework containing a distributed knowledge base that can support the data representation needs of tools, provide environmental support for the formalization and control of the software development process, and offer a highly interactive and consistent user interface.

Engine Structures Modeling Software System (ESMOSS)

NASA Technical Reports Server (NTRS)

1991-01-01

Engine Structures Modeling Software System (ESMOSS) is the development of a specialized software system for the construction of geometric descriptive and discrete analytical models of engine parts, components, and substructures which can be transferred to finite element analysis programs such as NASTRAN. The NASA Lewis Engine Structures Program is concerned with the development of technology for the rational structural design and analysis of advanced gas turbine engines with emphasis on advanced structural analysis, structural dynamics, structural aspects of aeroelasticity, and life prediction. Fundamental and common to all of these developments is the need for geometric and analytical model descriptions at various engine assembly levels which are generated using ESMOSS.

Increasing the reliability of ecological models using modern software engineering techniques

Treesearch

Robert M. Scheller; Brian R. Sturtevant; Eric J. Gustafson; Brendan C. Ward; David J. Mladenoff

2009-01-01

Modern software development techniques are largely unknown to ecologists. Typically, ecological models and other software tools are developed for limited research purposes, and additional capabilities are added later, usually in an ad hoc manner. Modern software engineering techniques can substantially increase scientific rigor and confidence in ecological models and...

Effects of the Meetings-Flow Approach on Quality Teamwork in the Training of Software Capstone Projects

ERIC Educational Resources Information Center

Chen, Chung-Yang; Hong, Ya-Chun; Chen, Pei-Chi

2014-01-01

Software development relies heavily on teamwork; determining how to streamline this collaborative development is an essential training subject in computer and software engineering education. A team process known as the meetings-flow (MF) approach has recently been introduced in software capstone projects in engineering programs at various…

Interpreting CMMI High Maturity for Small Organizations

DTIC Science & Technology

2008-09-01

Stoddard September, 2008 Congreso Internacional en Ingeniería de Software y sus Aplicaciones (International Congress of Software Engineering d...Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 Congreso Internacional en Ingeniería de Software y sus Aplicaciones (International Congress of...de Software y sus Aplicaciones (International Congress of Software Engineering and its Applications) Why This Workshop? CMMI Process Performance

OHD/HL - Staff

Science.gov Websites

Laboratory Branches Hydrologic Software Engineering Branch (HSEB) Hydrologic Science and Modeling Branch (HSMB) General Info Publications Documentation Software Standard and Guidelines Contact Us HL Staff resources and services. Staff Directory Chief, Hydrology Laboratory; Chief, Hydrologic Software Engineering

ETICS: the international software engineering service for the grid

NASA Astrophysics Data System (ADS)

Meglio, A. D.; Bégin, M.-E.; Couvares, P.; Ronchieri, E.; Takacs, E.

2008-07-01

The ETICS system is a distributed software configuration, build and test system designed to fulfil the needs of improving the quality, reliability and interoperability of distributed software in general and grid software in particular. The ETICS project is a consortium of five partners (CERN, INFN, Engineering Ingegneria Informatica, 4D Soft and the University of Wisconsin-Madison). The ETICS service consists of a build and test job execution system based on the Metronome software and an integrated set of web services and software engineering tools to design, maintain and control build and test scenarios. The ETICS system allows taking into account complex dependencies among applications and middleware components and provides a rich environment to perform static and dynamic analysis of the software and execute deployment, system and interoperability tests. This paper gives an overview of the system architecture and functionality set and then describes how the EC-funded EGEE, DILIGENT and OMII-Europe projects are using the software engineering services to build, validate and distribute their software. Finally a number of significant use and test cases will be described to show how ETICS can be used in particular to perform interoperability tests of grid middleware using the grid itself.

Assessing the Total Factor Productivity of Cotton Production in Egypt

PubMed Central

Rodríguez, Xosé A.; Elasraag, Yahia H.

2015-01-01

The main objective of this paper is to decompose the productivity growth of Egyptian cotton production. We employ the stochastic frontier approach and decompose the changes in total factor productivity (CTFP) growth into four components: technical progress (TP), changes in scale component (CSC), changes in allocative efficiency (CAE), and changes in technical efficiency (CTE). Considering a situation of scarce statistical information, we propose four alternative empirical models, with the purpose of looking for convergence in the results. The results provide evidence that in this production system total productivity does not increase, which is mainly due to the negative average contributions of CAE and TP. Policy implications are offered in light of the results. PMID:25625318

Assessing the total factor productivity of cotton production in Egypt.

PubMed

Rodríguez, Xosé A; Elasraag, Yahia H

2015-01-01

The main objective of this paper is to decompose the productivity growth of Egyptian cotton production. We employ the stochastic frontier approach and decompose the changes in total factor productivity (CTFP) growth into four components: technical progress (TP), changes in scale component (CSC), changes in allocative efficiency (CAE), and changes in technical efficiency (CTE). Considering a situation of scarce statistical information, we propose four alternative empirical models, with the purpose of looking for convergence in the results. The results provide evidence that in this production system total productivity does not increase, which is mainly due to the negative average contributions of CAE and TP. Policy implications are offered in light of the results.

Testing Scientific Software: A Systematic Literature Review

PubMed Central

Kanewala, Upulee; Bieman, James M.

2014-01-01

Context Scientific software plays an important role in critical decision making, for example making weather predictions based on climate models, and computation of evidence for research publications. Recently, scientists have had to retract publications due to errors caused by software faults. Systematic testing can identify such faults in code. Objective This study aims to identify specific challenges, proposed solutions, and unsolved problems faced when testing scientific software. Method We conducted a systematic literature survey to identify and analyze relevant literature. We identified 62 studies that provided relevant information about testing scientific software. Results We found that challenges faced when testing scientific software fall into two main categories: (1) testing challenges that occur due to characteristics of scientific software such as oracle problems and (2) testing challenges that occur due to cultural differences between scientists and the software engineering community such as viewing the code and the model that it implements as inseparable entities. In addition, we identified methods to potentially overcome these challenges and their limitations. Finally we describe unsolved challenges and how software engineering researchers and practitioners can help to overcome them. Conclusions Scientific software presents special challenges for testing. Specifically, cultural differences between scientist developers and software engineers, along with the characteristics of the scientific software make testing more difficult. Existing techniques such as code clone detection can help to improve the testing process. Software engineers should consider special challenges posed by scientific software such as oracle problems when developing testing techniques. PMID:25125798

Naming in a Programming Support Environment.

DTIC Science & Technology

1984-02-01

and Control, 1974. 10. T. E. Cheatham. An Overview of the Harvard Program Development System. I; Software Engineering Environments, H. Hunke, Ed.. North...Holland Publishing Compary, 1981, pp. 253-266. 11. T. E. Cheatham. Comparing Programming Support Environments. In Software Engineering Environments...Company. 1981. Third Edition 16. F. DeRemer and H Kron Programming -inthe Large Versus Programming -in-theSmall. IEEE Transactions on Software Engineering

Data and Analysis Center for Software: An IAC in Transition.

DTIC Science & Technology

1983-06-01

reviewed and is approved for publication. * APPROVEDt Proj ect Engineer . JOHN J. MARCINIAK, Colonel, USAF Chief, Command and Control Division . FOR THE CO...SUPPLEMENTARY NOTES RADC Project Engineer : John Palaimo (COEE) It. KEY WORDS (Conilnuo n rever*e aide if necessary and identify by block numober...Software Engineering Software Technology Information Analysis Center Database Scientific and Technical Information 20. ABSTRACT (Continue on reverse side It

Interoperability in the e-Government Context

DTIC Science & Technology

2012-01-01

Mellon University for the operation of the Software Engineering Institute, a federally funded research and development center. Any opinions...Hanscom AFB, MA 01731-2125 NO WARRANTY THIS CARNEGIE MELLON UNIVERSITY AND SOFTWARE ENGINEERING INSTITUTE MATERIAL IS FURNISHED ON AN “AS-IS” BASIS... Software Engineering Institute at permission@sei.cmu.edu. * These restrictions do not apply to U.S. government entities. CMU/SEI-2011-TN-014 | i Table

Software Safety Risk in Legacy Safety-Critical Computer Systems

NASA Technical Reports Server (NTRS)

Hill, Janice; Baggs, Rhoda

2007-01-01

Safety-critical computer systems must be engineered to meet system and software safety requirements. For legacy safety-critical computer systems, software safety requirements may not have been formally specified during development. When process-oriented software safety requirements are levied on a legacy system after the fact, where software development artifacts don't exist or are incomplete, the question becomes 'how can this be done?' The risks associated with only meeting certain software safety requirements in a legacy safety-critical computer system must be addressed should such systems be selected as candidates for reuse. This paper proposes a method for ascertaining formally, a software safety risk assessment, that provides measurements for software safety for legacy systems which may or may not have a suite of software engineering documentation that is now normally required. It relies upon the NASA Software Safety Standard, risk assessment methods based upon the Taxonomy-Based Questionnaire, and the application of reverse engineering CASE tools to produce original design documents for legacy systems.

Impact of Ada and object-oriented design in the flight dynamics division at Goddard Space Flight Center

NASA Technical Reports Server (NTRS)

Waligora, Sharon; Bailey, John; Stark, Mike

1995-01-01

The Software Engineering Laboratory (SEL) is an organization sponsored by NASA/GSFC and created to investigate the effectiveness of software engineering technologies when applied to the development of applications software. The goals of the SEL are (1) to understand the software development process in the GSFC environment; (2) to measure the effects of various methodologies, tools, and models on this process; and (3) to identify and then to apply successful development practices. The activities, findings, and recommendations of the SEL are recorded in the Software Engineering Laboratory Series, a continuing series of reports that includes this document.

Software Engineering Research/Developer Collaborations in 2005

NASA Technical Reports Server (NTRS)

Pressburger, Tom

2006-01-01

In CY 2005, three collaborations between software engineering technology providers and NASA software development personnel deployed three software engineering technologies on NASA development projects (a different technology on each project). The main purposes were to benefit the projects, infuse the technologies if beneficial into NASA, and give feedback to the technology providers to improve the technologies. Each collaboration project produced a final report. Section 2 of this report summarizes each project, drawing from the final reports and communications with the software developers and technology providers. Section 3 indicates paths to further infusion of the technologies into NASA practice. Section 4 summarizes some technology transfer lessons learned. Also included is an acronym list.

Certified Binaries for Software Components

DTIC Science & Technology

2007-09-01

is sponsored by the U.S. Department of Defense. The Software Engineering Institute is a federally funded research and development center sponsored...by the U.S. Department of Defense. Copyright 2007 Carnegie Mellon University. NO WARRANTY THIS CARNEGIE MELLON UNIVERSITY AND SOFTWARE ENGINEERING

An information model for use in software management estimation and prediction

NASA Technical Reports Server (NTRS)

Li, Ningda R.; Zelkowitz, Marvin V.

1993-01-01

This paper describes the use of cluster analysis for determining the information model within collected software engineering development data at the NASA/GSFC Software Engineering Laboratory. We describe the Software Management Environment tool that allows managers to predict development attributes during early phases of a software project and the modifications we propose to allow it to develop dynamic models for better predictions of these attributes.

CrossTalk: The Journal of Defense Software Engineering. Volume 18, Number 9

DTIC Science & Technology

2005-09-01

2004. 12. Humphrey , Watts . Introduction to the Personal Software Process SM. Addison- Wesley 1997. 13. Humphrey , Watts . Introduction to the Team...Personal Software ProcessSM (PSPSM)is a software development process orig- inated by Watts Humphrey at the Software Engineering Institute (SEI) in the...meets its commitments and bring a sense of control and predictability into an apparently chaotic project.u References 1. Humphrey , Watts . Coaching

Sandia National Laboratories Advanced Simulation and Computing (ASC) software quality plan : ASC software quality engineering practices Version 3.0.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Turgeon, Jennifer L.; Minana, Molly A.; Hackney, Patricia

2009-01-01

The purpose of the Sandia National Laboratories (SNL) Advanced Simulation and Computing (ASC) Software Quality Plan is to clearly identify the practices that are the basis for continually improving the quality of ASC software products. Quality is defined in the US Department of Energy/National Nuclear Security Agency (DOE/NNSA) Quality Criteria, Revision 10 (QC-1) as 'conformance to customer requirements and expectations'. This quality plan defines the SNL ASC Program software quality engineering (SQE) practices and provides a mapping of these practices to the SNL Corporate Process Requirement (CPR) 001.3.6; 'Corporate Software Engineering Excellence'. This plan also identifies ASC management's and themore » software project teams responsibilities in implementing the software quality practices and in assessing progress towards achieving their software quality goals. This SNL ASC Software Quality Plan establishes the signatories commitments to improving software products by applying cost-effective SQE practices. This plan enumerates the SQE practices that comprise the development of SNL ASC's software products and explains the project teams opportunities for tailoring and implementing the practices.« less

Using UML Modeling to Facilitate Three-Tier Architecture Projects in Software Engineering Courses

ERIC Educational Resources Information Center

Mitra, Sandeep

2014-01-01

This article presents the use of a model-centric approach to facilitate software development projects conforming to the three-tier architecture in undergraduate software engineering courses. Many instructors intend that such projects create software applications for use by real-world customers. While it is important that the first version of these…

Design of High Altitude Long Endurance UAV: Structural Analysis of Composite Wing using Finite Element Method

NASA Astrophysics Data System (ADS)

Kholish Rumayshah, Khodijah; Prayoga, Aditya; Mochammad Agoes Moelyadi, Ing., Dr.

2018-04-01

Research on a High Altitude Long Endurance (HALE) Unmanned Aerial Vehicle (UAV) is currently being conducted at Bandung Institute of Technology (ITB). Previously, the 1st generation of HALE UAV ITB used balsa wood for most of its structure. Flight test gave the result of broken wings due to extreme side-wind that causes large bending to its high aspect ratio wing. This paper conducted a study on designing the 2nd generation of HALE UAV ITB which used composite materials in order to substitute balsa wood at some critical parts of the wing’s structure. Finite element software ABAQUS/CAE is used to predict the stress and deformation that occurred. Tsai-Wu and Von-Mises failure criteria were applied to check whether the structure failed or not. The initial configuration gave the results that the structure experienced material failure. A second iteration was done by proposing a new configuration and it was proven safe against the load given.

Survey on Intelligent Assistance for Workplace Learning in Software Engineering

NASA Astrophysics Data System (ADS)

Ras, Eric; Rech, Jörg

Technology-enhanced learning (TEL) systems and intelligent assistance systems aim at supporting software engineers during learning and work. A questionnaire-based survey with 89 responses from industry was conducted to find out what kinds of services should be provided and how, as well as to determine which software engineering phases they should focus on. In this paper, we present the survey results regarding intelligent assistance for workplace learning in software engineering. We analyzed whether specific types of assistance depend on the organization's size, the respondent's role, and the experience level. The results show a demand for TEL that supports short-term problem solving and long-term competence development at the workplace.

Automated software development workstation

NASA Technical Reports Server (NTRS)

Prouty, Dale A.; Klahr, Philip

1988-01-01

A workstation is being developed that provides a computational environment for all NASA engineers across application boundaries, which automates reuse of existing NASA software and designs, and efficiently and effectively allows new programs and/or designs to be developed, catalogued, and reused. The generic workstation is made domain specific by specialization of the user interface, capturing engineering design expertise for the domain, and by constructing/using a library of pertinent information. The incorporation of software reusability principles and expert system technology into this workstation provide the obvious benefits of increased productivity, improved software use and design reliability, and enhanced engineering quality by bringing engineering to higher levels of abstraction based on a well tested and classified library.

V & V Within Reuse-Based Software Engineering

NASA Technical Reports Server (NTRS)

Addy, Edward A.

1996-01-01

Verification and validation (V&V) is used to increase the level of assurance of critical software, particularly that of safety-critical and mission critical software. This paper describes the working group's success in identifying V&V tasks that could be performed in the domain engineering and transition levels of reuse-based software engineering. The primary motivation for V&V at the domain level is to provide assurance that the domain requirements are correct and that the domain artifacts correctly implement the domain requirements. A secondary motivation is the possible elimination of redundant V&V activities at the application level. The group also considered the criteria and motivation for performing V&V in domain engineering.

Resilience Engineering in Critical Long Term Aerospace Software Systems: A New Approach to Spacecraft Software Safety

NASA Astrophysics Data System (ADS)

Dulo, D. A.

Safety critical software systems permeate spacecraft, and in a long term venture like a starship would be pervasive in every system of the spacecraft. Yet software failure today continues to plague both the systems and the organizations that develop them resulting in the loss of life, time, money, and valuable system platforms. A starship cannot afford this type of software failure in long journeys away from home. A single software failure could have catastrophic results for the spaceship and the crew onboard. This paper will offer a new approach to developing safe reliable software systems through focusing not on the traditional safety/reliability engineering paradigms but rather by focusing on a new paradigm: Resilience and Failure Obviation Engineering. The foremost objective of this approach is the obviation of failure, coupled with the ability of a software system to prevent or adapt to complex changing conditions in real time as a safety valve should failure occur to ensure safe system continuity. Through this approach, safety is ensured through foresight to anticipate failure and to adapt to risk in real time before failure occurs. In a starship, this type of software engineering is vital. Through software developed in a resilient manner, a starship would have reduced or eliminated software failure, and would have the ability to rapidly adapt should a software system become unstable or unsafe. As a result, long term software safety, reliability, and resilience would be present for a successful long term starship mission.

Integration of Wind Turbines with Compressed Air Energy Storage

NASA Astrophysics Data System (ADS)

Arsie, I.; Marano, V.; Rizzo, G.; Moran, M.

2009-08-01

Some of the major limitations of renewable energy sources are represented by their low power density and intermittent nature, largely depending upon local site and unpredictable weather conditions. These problems concur to increase the unit costs of wind power, so limiting their diffusion. By coupling storage systems with a wind farm, some of the major limitations of wind power, such as a low power density and an unpredictable nature, can be overcome. After an overview on storage systems, the Compressed Air Energy Storage (CAES) is analyzed, and the state of art on such systems is discussed. A Matlab/Simulink model of a hybrid power plant consisting of a wind farm coupled with CAES is then presented. The model has been successfully validated starting from the operating data of the McIntosh CAES Plant in Alabama. Time-series neural network-based wind speed forecasting are employed to determine the optimal daily operation strategy for the storage system. A detailed economic analysis has been carried out: investment and maintenance costs are estimated based on literature data, while operational costs and revenues are calculated according to energy market prices. As shown in the paper, the knowledge of the expected available energy is a key factor to optimize the management strategies of the proposed hybrid power plant, allowing to obtain environmental and economic benefits.

Complexity Measure for the Prototype System Description Language (PSDL)

DTIC Science & Technology

2002-06-01

Albrecht, A. and Gaffney , J., Software Function Source Lines of Code and Development Effort Prediction, IEEE Transactions on Software Engineering...Through Meausrement”; Proceedings of the IEEE, Vol. 77, No. 4, April 89. Schach, Stephen, R., Software Engineering, Second Edition, IRWIN, Burr Ridge

The Hidden Job Requirements for a Software Engineer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marinovici, Maria C.; Kirkham, Harold; Glass, Kevin A.

In a world increasingly operated by computers, where innovation depends on software, the software engineer’s role is changing continuously and gaining new dimensions. In commercial software development as well as scientific research environments, the way software developers are perceived is changing, because they are more important to the business than ever before. Nowadays, their job requires skills extending beyond the regular job description posted by HR, and more is expected. To advance and thrive in their new roles, the software engineers must embrace change, and practice the themes of the new era (integration, collaboration and optimization). The challenges may bemore » somehow intimidating for freshly graduated software engineers. Through this paper the authors hope to set them on a path for success, by helping them relinquish their fear of the unknown.« less

The Generalized Support Software (GSS) Domain Engineering Process: An Object-Oriented Implementation and Reuse Success at Goddard Space Flight Center

NASA Technical Reports Server (NTRS)

Condon, Steven; Hendrick, Robert; Stark, Michael E.; Steger, Warren

1997-01-01

The Flight Dynamics Division (FDD) of NASA's Goddard Space Flight Center (GSFC) recently embarked on a far-reaching revision of its process for developing and maintaining satellite support software. The new process relies on an object-oriented software development method supported by a domain specific library of generalized components. This Generalized Support Software (GSS) Domain Engineering Process is currently in use at the NASA GSFC Software Engineering Laboratory (SEL). The key facets of the GSS process are (1) an architecture for rapid deployment of FDD applications, (2) a reuse asset library for FDD classes, and (3) a paradigm shift from developing software to configuring software for mission support. This paper describes the GSS architecture and process, results of fielding the first applications, lessons learned, and future directions

In-Plant Technical Assistance for Software

DTIC Science & Technology

1986-09-29

engineer who has had a few programming courses (or send him to a few), and then he will be your software engineer." ( Pressman , 1982.)* Generally, It...1984. Program Office/AFCMD Interface. AFSCR 800-42, November 1982. Pressman , Roger S., Software Engineering. McGraw-Hill, New York, 1982. Dennis...B.M.C., Norton AFB Darrah Whitlock QA Specialist, Plans & Eval. Branch Rockwell-Anaheim AFPRO Lt. Col. Barry Prins HQ/AFCMD Kirtland AFB Stan

Warfighting Concepts to Future Weapon System Designs (WARCON)

DTIC Science & Technology

2003-09-12

34* Software design documents rise to litigation. "* A Material List "Cost information that may support, or may * Final Engineering Process Maps be...document may include design the system as derived from the engineering design, software development, SRD. MTS Technologies, Inc. 26 FOR OFFICIAL USE...document, early in the development phase. It is software engineers produce the vision of important to establish a standard, formal the design effort. As

Building Safer Systems With SpecTRM

NASA Technical Reports Server (NTRS)

2003-01-01

System safety, an integral component in software development, often poses a challenge to engineers designing computer-based systems. While the relaxed constraints on software design allow for increased power and flexibility, this flexibility introduces more possibilities for error. As a result, system engineers must identify the design constraints necessary to maintain safety and ensure that the system and software design enforces them. Safeware Engineering Corporation, of Seattle, Washington, provides the information, tools, and techniques to accomplish this task with its Specification Tools and Requirements Methodology (SpecTRM). NASA assisted in developing this engineering toolset by awarding the company several Small Business Innovation Research (SBIR) contracts with Ames Research Center and Langley Research Center. The technology benefits NASA through its applications for Space Station rendezvous and docking. SpecTRM aids system and software engineers in developing specifications for large, complex safety critical systems. The product enables engineers to find errors early in development so that they can be fixed with the lowest cost and impact on the system design. SpecTRM traces both the requirements and design rationale (including safety constraints) throughout the system design and documentation, allowing engineers to build required system properties into the design from the beginning, rather than emphasizing assessment at the end of the development process when changes are limited and costly.System safety, an integral component in software development, often poses a challenge to engineers designing computer-based systems. While the relaxed constraints on software design allow for increased power and flexibility, this flexibility introduces more possibilities for error. As a result, system engineers must identify the design constraints necessary to maintain safety and ensure that the system and software design enforces them. Safeware Engineering Corporation, of Seattle, Washington, provides the information, tools, and techniques to accomplish this task with its Specification Tools and Requirements Methodology (SpecTRM). NASA assisted in developing this engineering toolset by awarding the company several Small Business Innovation Research (SBIR) contracts with Ames Research Center and Langley Research Center. The technology benefits NASA through its applications for Space Station rendezvous and docking. SpecTRM aids system and software engineers in developing specifications for large, complex safety critical systems. The product enables engineers to find errors early in development so that they can be fixed with the lowest cost and impact on the system design. SpecTRM traces both the requirements and design rationale (including safety constraints) throughout the system design and documentation, allowing engineers to build required system properties into the design from the beginning, rather than emphasizing assessment at the end of the development process when changes are limited and costly.

The Use of the Software MATLAB To Improve Chemical Engineering Education.

ERIC Educational Resources Information Center

Damatto, T.; Maegava, L. M.; Filho, R. Maciel

In all the Brazilian Universities involved with the project "Prodenge-Reenge", the main objective is to improve teaching and learning procedures for the engineering disciplines. The Chemical Engineering College of Campinas State University focused its effort on the use of engineering softwares. The work developed by this project has…

A β-cyclodextrin, polyethyleneimine and silk fibroin hydrogel containing Centella asiatica extract and hydrocortisone acetate: releasing properties and in vivo efficacy for healing of pressure sores.

PubMed

Lee, M S; Seo, S R; Kim, J-C

2012-10-01

  Pressure sores are lesions caused by impaired blood flow. Conventional dressings can absorb exudates, but do not promote wound healing. A hydrogel composed of β-cyclodextrin (β-CD), polyethyleneimine (PEI) and silk fibroin (SF) was assessed for use in healing of pressure sores. The hydrogel was prepared by crosslinking β-CD-grafted PEI and SF using epichlorohydrin. The gel was then immersed in an aqueous solution of Centella asiatica extract (CAE) 0.7 mg/mL and/or hydrocortisone acetate (HCA) 0.5 mg/mL. The in vivo pressure sore-healing efficacy of the dry gel (with or without the drugs) was investigated in terms of the hyperplasia of epidermis and the number of neutrophils in the skin tissue. The specific loading of CAE was 0.0091 g/g of dry gel. The percentage of CAE released at 24 h at pH 3.0, 5.0 and 7.4 was approximately 63.9%, 55.0% and 44.4%, respectively. This pH-dependent release is possibly due to the degree of gel swelling, which decreased with increasing pH. The specific loading of HCA was 0.0050 g/g dry gel, and the percentage release of HCA at 24 h was around 20% at all three pH points. It is likely that HCA release is independent of pH. HCA is a hydrophobic compound, and therefore the release of HCA is affected by the partitioning of HCA between the β-CD cavity and the bulk water phase, but not by the degree of swelling of the hydrogel. The pressure sores treated with the hydrogel healed in 6 days, compared with 10 days for controls. In this study, a β-CD/PEI/SF hydrogel containing CAE and HCA reduced the healing time for pressure sores. © The Author(s). CED © 2012 British Association of Dermatologists.

The Center for Astronomy Education (CAE) Ushers in a New Community-Based Model for Astronomy Education Research with the NSF Funded CCLI Phase III Collaboration of Astronomy Teaching Scholars (CATS) Program

NASA Astrophysics Data System (ADS)

Brissenden, Gina; Impey, C.; Prather, E.; Lee, K.; Duncan, D.

2009-01-01

The Center for Astronomy Education (CAE) has been devoted to improving teaching & learning in Astro 101 by creating research-validated curriculum & assessment instruments for use in Astro 101 & by providing Astro 101 instructors professional development opportunities to increase their pedagogical content knowledge & instructional skills at implementing these curricula & assessment materials. To create sustainability and further expand this work, CAE, in collaboration with other national leaders in astronomy education & research, developed the Collaboration of Astronomy Teaching Scholars (CATS) Program. The primary goals of CATS are to: 1) increase the number of Astro 101 instructors conducting fundamental research in astronomy education 2) increase the amount of research-validated curriculum & assessment instruments available for use in Astro 101 3) increase the number of people prepared to develop & conduct their own CAE Teaching Excellence Workshops In our first year we have concluded a national study assessing the teaching & learning of Astro 101 & the effect of interactive instruction. We have begun the initial analysis of the demographics data of this study. We have begun a classroom research validation study on the use of the "ClassAction” electronic learning system. We have begun to analyze data from two different studies on students’ attitudes & understanding of science to inform the creation of an assessment instrument designed specifically for Astro 101 to evaluate the effectiveness of our instruction in improving students’ attitudes & beliefs about science. We have also begun the development of a Solar System Concept Inventory. Additionally the development of the Solar System Concept Inventory and research into students’ beliefs and reasoning difficulties on topics in Cosmology are well underway. We acknowledge the NSF for funding under Award No. 0715517, a CCLI Phase III Grant for the Collaboration of Astronomy Teaching Scholars (CATS) Program.

Caltrans WeatherShare Phase II System: An Application of Systems and Software Engineering Process to Project Development

DOT National Transportation Integrated Search

2009-08-25

In cooperation with the California Department of Transportation, Montana State University's Western Transportation Institute has developed the WeatherShare Phase II system by applying Systems Engineering and Software Engineering processes. The system...

Type Safe Extensible Programming

NASA Astrophysics Data System (ADS)

Chae, Wonseok

2009-10-01

Software products evolve over time. Sometimes they evolve by adding new features, and sometimes by either fixing bugs or replacing outdated implementations with new ones. When software engineers fail to anticipate such evolution during development, they will eventually be forced to re-architect or re-build from scratch. Therefore, it has been common practice to prepare for changes so that software products are extensible over their lifetimes. However, making software extensible is challenging because it is difficult to anticipate successive changes and to provide adequate abstraction mechanisms over potential changes. Such extensibility mechanisms, furthermore, should not compromise any existing functionality during extension. Software engineers would benefit from a tool that provides a way to add extensions in a reliable way. It is natural to expect programming languages to serve this role. Extensible programming is one effort to address these issues. In this thesis, we present type safe extensible programming using the MLPolyR language. MLPolyR is an ML-like functional language whose type system provides type-safe extensibility mechanisms at several levels. After presenting the language, we will show how these extensibility mechanisms can be put to good use in the context of product line engineering. Product line engineering is an emerging software engineering paradigm that aims to manage variations, which originate from successive changes in software.

Collected software engineering papers, volume 8

NASA Technical Reports Server (NTRS)

1990-01-01

A collection of selected technical papers produced by participants in the Software Engineering Laboratory (SEL) during the period November 1989 through October 1990 is presented. The purpose of the document is to make available, in one reference, some results of SEL research that originally appeared in a number of different forums. Although these papers cover several topics related to software engineering, they do not encompass the entire scope of SEL activities and interests. Additional information about the SEL and its research efforts may be obtained from the sources listed in the bibliography. The seven presented papers are grouped into four major categories: (1) experimental research and evaluation of software measurement; (2) studies on models for software reuse; (3) a software tool evaluation; and (4) Ada technology and studies in the areas of reuse and specification.

Experimental software engineering: Seventeen years of lessons in the SEL

NASA Technical Reports Server (NTRS)

Mcgarry, Frank E.

1992-01-01

Seven key principles developed by the Software Engineering Laboratory (SEL) at the Goddard Space Flight Center (GSFC) of the National Aeronautics and Space Administration (NASA) are described. For the past 17 years, the SEL has been experimentally analyzing the development of production software as varying techniques and methodologies are applied in this one environment. The SEL has collected, archived, and studied detailed measures from more than 100 flight dynamics projects, thereby gaining significant insight into the effectiveness of numerous software techniques, as well as extensive experience in the overall effectiveness of 'Experimental Software Engineering'. This experience has helped formulate follow-on studies in the SEL, and it has helped other software organizations better understand just what can be accomplished and what cannot be accomplished through experimentation.

Automated Reuse of Scientific Subroutine Libraries through Deductive Synthesis

NASA Technical Reports Server (NTRS)

Lowry, Michael R.; Pressburger, Thomas; VanBaalen, Jeffrey; Roach, Steven

1997-01-01

Systematic software construction offers the potential of elevating software engineering from an art-form to an engineering discipline. The desired result is more predictable software development leading to better quality and more maintainable software. However, the overhead costs associated with the formalisms, mathematics, and methods of systematic software construction have largely precluded their adoption in real-world software development. In fact, many mainstream software development organizations, such as Microsoft, still maintain a predominantly oral culture for software development projects; which is far removed from a formalism-based culture for software development. An exception is the limited domain of safety-critical software, where the high-assuiance inherent in systematic software construction justifies the additional cost. We believe that systematic software construction will only be adopted by mainstream software development organization when the overhead costs have been greatly reduced. Two approaches to cost mitigation are reuse (amortizing costs over many applications) and automation. For the last four years, NASA Ames has funded the Amphion project, whose objective is to automate software reuse through techniques from systematic software construction. In particular, deductive program synthesis (i.e., program extraction from proofs) is used to derive a composition of software components (e.g., subroutines) that correctly implements a specification. The construction of reuse libraries of software components is the standard software engineering solution for improving software development productivity and quality.

Generate an Optimum Lightweight Legs Structure Design Based on Critical Posture in A-FLoW Humanoid Robot

NASA Astrophysics Data System (ADS)

Luthfi, A.; Subhan, K. A.; Eko H, B.; Sanggar, D. R.; Pramadihanto, D.

2018-04-01

Lightweight construction and energy efficiency play an important role in humanoid robot development. The application of computer-aided engineering (CAE) in the development process is one of the possibilities to achieve the appropriate reduction of the weight. This paper describes a method to generate an optimum lightweight legs structure design based on critical posture during walking locomotion in A-FLoW Humanoid robot.The criticalposture can be obtained from the highest forces and moments in each joint of the robot body during walking locomotion. From the finite element analysis (FEA) result can be realized leg structure design of A-FLoW humanoid robot with a maximum displacement value of 0.05 mmand weight reduction about 0.598 Kg from the thigh structure and a maximum displacement value of 0,13 mmand weight reduction about 0.57 kg from the shin structure.

Ada Software Engineering Education and Training Requirements Within the U.S. Army

DTIC Science & Technology

1988-12-01

Services and DoD. DoD Directive 3405.1 requires the use of Ada in all applications and DoD Directive 3405.2 establishes the policy of using Ada in...covers DoD structure and procedures, Army policies , and all aspects of software engineering theory, systems engineering, and software development and...acquisition policy , concept development, workload requirements, contracting, and maintenance. The second course covers many of the same areas

Commonality and Variability Analysis for Xenon Family of Separation Virtual Machine Monitors (CVAX)

DTIC Science & Technology

2017-07-18

technical approach is a systematic application of Software Product Line Engineering (SPLE). A systematic application requires describing the family and... engineering Software family September 2016 – October 2016 OSD/OUSD/ATL/ASD(R&E)/RDOffice of Information Systems & Cyber Security RD / ASD(R&E) / AT&L...by the evolving open-source Xen hypervisor. The technical approach is a systematic application of Software Product Line Engineering (SPLE). A

CrossTalk: The Journal of Defense Software Engineering. Volume 21, Number 9

DTIC Science & Technology

2008-09-01

including suggestions for reducing this burden, to Washington Headquarters Services, Directorate for Information Operations and Reports, 1215 Jefferson...SEP 2008 2. REPORT TYPE 3. DATES COVERED 00-00-2008 to 00-00-2008 4. TITLE AND SUBTITLE CrossTalk: The Journal of Defense Software Engineering...The Journal of Defense Software Engineering September 2008 4 10 15 19 24 26 Securing Legacy C Applications Using Dynamic Data Flow Analysis This

Investigation of the current requirements engineering practices among software developers at the Universiti Utara Malaysia Information Technology (UUMIT) centre

NASA Astrophysics Data System (ADS)

Hussain, Azham; Mkpojiogu, Emmanuel O. C.; Abdullah, Inam

2016-08-01

Requirements Engineering (RE) is a systemic and integrated process of eliciting, elaborating, negotiating, validating and managing of the requirements of a system in a software development project. UUM has been supported by various systems developed and maintained by the UUM Information Technology (UUMIT) Centre. The aim of this study was to assess the current requirements engineering practices at UUMIT. The main problem that prompted this research is the lack of studies that support software development activities at the UUMIT. The study is geared at helping UUMIT produce quality but time and cost saving software products by implementing cutting edge and state of the art requirements engineering practices. Also, the study contributes to UUM by identifying the activities needed for software development so that the management will be able to allocate budget to provide adequate and precise training for the software developers. Three variables were investigated: Requirement Description, Requirements Development (comprising: Requirements Elicitation, Requirements Analysis and Negotiation, Requirements Validation), and Requirement Management. The results from the study showed that the current practice of requirement engineering in UUMIT is encouraging, but still need further development and improvement because a few RE practices were seldom practiced.

Software engineering technology transfer: Understanding the process

NASA Technical Reports Server (NTRS)

Zelkowitz, Marvin V.

1993-01-01

Technology transfer is of crucial concern to both government and industry today. In this report, the mechanisms developed by NASA to transfer technology are explored and the actual mechanisms used to transfer software development technologies are investigated. Time, cost, and effectiveness of software engineering technology transfer is reported.

Information Systems and Software Engineering Research and Education in Oulu until the 1990s

NASA Astrophysics Data System (ADS)

Oinas-Kukkonen, Henry; Kerola, Pentti; Oinas-Kukkonen, Harri; Similä, Jouni; Pulli, Petri

This paper discusses the internationalization of software business in the Oulu region. Despite its small size, the region grew rapidly and very successfully into a global information and communication technology business center. The University of Oulu, which was the northern most university in the world at the time of its establishment (1958) had a strong emphasis on engineering since its very beginning. Research on electronics was carried out since the early 1960s. Later, when the Department of Information Processing Science was founded in 1969, research on information systems and later also on software engineering was carried out. This paper discusses the role of the information systems and software engineering research for the business growth of the region. Special emphasis is put on understanding the role of system-theoretical and software development expertise for transferring research knowledge into practice.

Towards a controlled vocabulary on software engineering education

NASA Astrophysics Data System (ADS)

Pizard, Sebastián; Vallespir, Diego

2017-11-01

Software engineering is the discipline that develops all the aspects of the production of software. Although there are guidelines about what topics to include in a software engineering curricula, it is usually unclear which are the best methods to teach them. In any science discipline the construction of a classification schema is a common approach to understand a thematic area. This study examines previous publications in software engineering education to obtain a first controlled vocabulary (a more formal definition of a classification schema) in the field. Publications from 1988 to 2014 were collected and processed using automatic clustering techniques and the outcomes were analysed manually. The result is an initial controlled vocabulary with a taxonomy form with 43 concepts that were identified as the most used in the research publications. We present the classification of the concepts in three facets: 'what to teach', 'how to teach' and 'where to teach' and the evolution of concepts over time.

Factors that Influence First-Career Choice of Undergraduate Engineers in Software Services Companies: A South Indian Experience

ERIC Educational Resources Information Center

Gokuladas, V. K.

2010-01-01

Purpose: The purpose of this paper is to identify how undergraduate engineering students differ in their perception about software services companies in India based on variables like gender, locations of the college and branches of engineering. Design/methodology/approach: Data obtained from 560 undergraduate engineering students who had the…

Mental Models of Software Forecasting

NASA Technical Reports Server (NTRS)

Hihn, J.; Griesel, A.; Bruno, K.; Fouser, T.; Tausworthe, R.

1993-01-01

The majority of software engineers resist the use of the currently available cost models. One problem is that the mathematical and statistical models that are currently available do not correspond with the mental models of the software engineers. In an earlier JPL funded study (Hihn and Habib-agahi, 1991) it was found that software engineers prefer to use analogical or analogy-like techniques to derive size and cost estimates, whereas curren CER's hide any analogy in the regression equations. In addition, the currently available models depend upon information which is not available during early planning when the most important forecasts must be made.

The Environment for Application Software Integration and Execution (EASIE) version 1.0. Volume 1: Executive overview

NASA Technical Reports Server (NTRS)

Rowell, Lawrence F.; Davis, John S.

1989-01-01

The Environment for Application Software Integration and Execution (EASIE) provides a methodology and a set of software utility programs to ease the task of coordinating engineering design and analysis codes. EASIE was designed to meet the needs of conceptual design engineers that face the task of integrating many stand-alone engineering analysis programs. Using EASIE, programs are integrated through a relational database management system. Volume 1, Executive Overview, gives an overview of the functions provided by EASIE and describes their use. Three operational design systems based upon the EASIE software are briefly described.

Software engineering project management - A state-of-the-art report

NASA Technical Reports Server (NTRS)

Thayer, R. H.; Lehman, J. H.

1977-01-01

The management of software engineering projects in the aerospace industry was investigated. The survey assessed such features as contract type, specification preparation techniques, software documentation required by customers, planning and cost-estimating, quality control, the use of advanced program practices, software tools and test procedures, the education levels of project managers, programmers and analysts, work assignment, automatic software monitoring capabilities, design and coding reviews, production times, success rates, and organizational structure of the projects.

The Cloud-Based Integrated Data Viewer (IDV)

NASA Astrophysics Data System (ADS)

Fisher, Ward

2015-04-01

Maintaining software compatibility across new computing environments and the associated underlying hardware is a common problem for software engineers and scientific programmers. While there are a suite of tools and methodologies used in traditional software engineering environments to mitigate this issue, they are typically ignored by developers lacking a background in software engineering. The result is a large body of software which is simultaneously critical and difficult to maintain. Visualization software is particularly vulnerable to this problem, given the inherent dependency on particular graphics hardware and software API's. The advent of cloud computing has provided a solution to this problem, which was not previously practical on a large scale; Application Streaming. This technology allows a program to run entirely on a remote virtual machine while still allowing for interactivity and dynamic visualizations, with little-to-no re-engineering required. Through application streaming we are able to bring the same visualization to a desktop, a netbook, a smartphone, and the next generation of hardware, whatever it may be. Unidata has been able to harness Application Streaming to provide a tablet-compatible version of our visualization software, the Integrated Data Viewer (IDV). This work will examine the challenges associated with adapting the IDV to an application streaming platform, and include a brief discussion of the underlying technologies involved. We will also discuss the differences between local software and software-as-a-service.

A comparative analysis of the value of pure and hybrid electricity storage

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sioshansi, Ramteen; Denholm, Paul; Jenkin, Thomas

2010-06-13

Significant natural gas and electricity price variation and volatility, especially during the past few years, raise questions about understanding the value drivers behind electricity storage. The impact of these drivers for pure storage (such as pumped hydroelectric storage) and compressed air energy storage (CAES) are different and in this paper we explore these differences in operation and net revenue over a variety of timescales. We also consider the arbitrage value that is attainable in practice and explain why simple forecasting techniques based on historical data will generally be less successful for CAES. Furthermore, the breakeven cost of storage and howmore » this can depend on regulatory treatment of storage and market structure is also considered.« less