48 CFR 36.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... with architect-engineer firms. 36.209 Section 36.209 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 36.209 Construction contracts with architect-engineer firms. No...

48 CFR 636.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... with architect-engineer firms. 636.209 Section 636.209 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 636.209 Construction contracts with architect-engineer firms. The...

48 CFR 636.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... with architect-engineer firms. 636.209 Section 636.209 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 636.209 Construction contracts with architect-engineer firms. The...

48 CFR 636.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... with architect-engineer firms. 636.209 Section 636.209 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 636.209 Construction contracts with architect-engineer firms. The...

48 CFR 636.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... with architect-engineer firms. 636.209 Section 636.209 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 636.209 Construction contracts with architect-engineer firms. The...

48 CFR 36.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... with architect-engineer firms. 36.209 Section 36.209 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 36.209 Construction contracts with architect-engineer firms. No...

48 CFR 636.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... with architect-engineer firms. 636.209 Section 636.209 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 636.209 Construction contracts with architect-engineer firms. The...

48 CFR 2936.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer firms. 2936.209 Section 2936.209 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 2936.209 Construction contracts with architect-engineer firms. As required by FAR...

48 CFR 36.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... with architect-engineer firms. 36.209 Section 36.209 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 36.209 Construction contracts with architect-engineer firms. No...

48 CFR 36.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... with architect-engineer firms. 36.209 Section 36.209 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 36.209 Construction contracts with architect-engineer firms. No...

48 CFR 36.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... with architect-engineer firms. 36.209 Section 36.209 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 36.209 Construction contracts with architect-engineer firms. No...

Mechanical preconditioning enables electrophysiologic coupling of skeletal myoblast cells to myocardium

PubMed Central

Treskes, Philipp; Cowan, Douglas B.; Stamm, Christof; Rubach, Martin; Adelmann, Roland; Wittwer, Thorsten; Wahlers, Thorsten

2015-01-01

Objective The effect of mechanical preconditioning on skeletal myoblasts in engineered tissue constructs was investigated to resolve issues associated with conduction block between skeletal myoblast cells and cardiomyocytes. Methods Murine skeletal myoblasts were used to generate engineered tissue constructs with or without application of mechanical strain. After in vitro myotube formation, engineered tissue constructs were co-cultured for 6 days with viable embryonic heart slices. With the use of sharp electrodes, electrical coupling between engineered tissue constructs and embryonic heart slices was assessed in the presence or absence of pharmacologic agents. Results The isolation and expansion procedure for skeletal myoblasts resulted in high yields of homogeneously desmin-positive (97.1% ± 0.1%) cells. Mechanical strain was exerted on myotubes within engineered tissue constructs during gelation of the matrix, generating preconditioned engineered tissue constructs. Electrical coupling between preconditioned engineered tissue constructs and embryonic heart slices was observed; however, no coupling was apparent when engineered tissue constructs were not subjected to mechanical strain. Coupling of cells from engineered tissue constructs to cells in embryonic heart slices showed slower conduction velocities than myocardial cells with the embryonic heart slices (preconditioned engineered tissue constructs vs embryonic heart slices: 0.04 ± 0.02 ms vs 0.10 ± 0.05 ms, P = .011), lower stimulation frequencies (preconditioned engineered tissue constructs vs maximum embryonic heart slices: 4.82 ± 1.42 Hz vs 10.58 ± 1.56 Hz; P = .0009), and higher sensitivities to the gap junction inhibitor (preconditioned engineered tissue constructs vs embryonic heart slices: 0.22 ± 0.07 mmol/L vs 0.93 ± 0.15 mmol/L; P = .0004). Conclusions We have generated skeletal myoblast–based transplantable grafts that electrically couple to myocardium. PMID:22980065

22 CFR 228.17 - Special procurement rules for construction and engineering services.

Code of Federal Regulations, 2012 CFR

2012-04-01

... engineering services. 228.17 Section 228.17 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES FOR... construction and engineering services. Advanced developing countries, as defined in § 228.01, which USAID has... engineering services are not eligible to furnish USAID-financed construction and engineering services unless...

22 CFR 228.17 - Special procurement rules for construction and engineering services.

Code of Federal Regulations, 2013 CFR

2013-04-01

... engineering services. 228.17 Section 228.17 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES FOR... construction and engineering services. Advanced developing countries, as defined in § 228.01, which USAID has... engineering services are not eligible to furnish USAID-financed construction and engineering services unless...

22 CFR 228.17 - Special procurement rules for construction and engineering services.

Code of Federal Regulations, 2014 CFR

2014-04-01

... engineering services. 228.17 Section 228.17 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES FOR... construction and engineering services. Advanced developing countries, as defined in § 228.01, which USAID has... engineering services are not eligible to furnish USAID-financed construction and engineering services unless...

48 CFR 31.201-7 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

...-engineer contracts. 31.201-7 Section 31.201-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Organizations 31.201-7 Construction and architect-engineer contracts. Specific principles and procedures for... architect-engineer contracts related to construction projects, are in 31.105. The applicability of these...

48 CFR 31.201-7 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

...-engineer contracts. 31.201-7 Section 31.201-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Organizations 31.201-7 Construction and architect-engineer contracts. Specific principles and procedures for... architect-engineer contracts related to construction projects, are in 31.105. The applicability of these...

48 CFR 31.201-7 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

...-engineer contracts. 31.201-7 Section 31.201-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Organizations 31.201-7 Construction and architect-engineer contracts. Specific principles and procedures for... architect-engineer contracts related to construction projects, are in 31.105. The applicability of these...

48 CFR 31.201-7 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

...-engineer contracts. 31.201-7 Section 31.201-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Organizations 31.201-7 Construction and architect-engineer contracts. Specific principles and procedures for... architect-engineer contracts related to construction projects, are in 31.105. The applicability of these...

48 CFR 31.201-7 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

...-engineer contracts. 31.201-7 Section 31.201-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Organizations 31.201-7 Construction and architect-engineer contracts. Specific principles and procedures for... architect-engineer contracts related to construction projects, are in 31.105. The applicability of these...

30 CFR 36.23 - Engine intake system.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Engine intake system. 36.23 Section 36.23... EQUIPMENT Construction and Design Requirements § 36.23 Engine intake system. (a) Construction. The intake... operator's compartment, to shut off the air supply to the engine. This valve shall be constructed to permit...

30 CFR 36.23 - Engine intake system.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Engine intake system. 36.23 Section 36.23... EQUIPMENT Construction and Design Requirements § 36.23 Engine intake system. (a) Construction. The intake... operator's compartment, to shut off the air supply to the engine. This valve shall be constructed to permit...

25 CFR 700.465 - Technical feasibility.

Code of Federal Regulations, 2010 CFR

2010-04-01

... construction, technology, or another engineering project, however, an application for a construction, technology or another engineering project shall: (a) Include sufficient information to determine the nature... construction, technology, or other engineering project prior to construction. The Commission shall review the...

25 CFR 700.465 - Technical feasibility.

Code of Federal Regulations, 2012 CFR

2012-04-01

... construction, technology, or another engineering project, however, an application for a construction, technology or another engineering project shall: (a) Include sufficient information to determine the nature... construction, technology, or other engineering project prior to construction. The Commission shall review the...

25 CFR 700.465 - Technical feasibility.

Code of Federal Regulations, 2014 CFR

2014-04-01

... construction, technology, or another engineering project, however, an application for a construction, technology or another engineering project shall: (a) Include sufficient information to determine the nature... construction, technology, or other engineering project prior to construction. The Commission shall review the...

25 CFR 700.465 - Technical feasibility.

Code of Federal Regulations, 2011 CFR

2011-04-01

... construction, technology, or another engineering project, however, an application for a construction, technology or another engineering project shall: (a) Include sufficient information to determine the nature... construction, technology, or other engineering project prior to construction. The Commission shall review the...

25 CFR 700.465 - Technical feasibility.

Code of Federal Regulations, 2013 CFR

2013-04-01

... construction, technology, or another engineering project, however, an application for a construction, technology or another engineering project shall: (a) Include sufficient information to determine the nature... construction, technology, or other engineering project prior to construction. The Commission shall review the...

7 CFR 1717.604 - Long-range engineering plans and construction work plans.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 11 2010-01-01 2010-01-01 false Long-range engineering plans and construction work... AND GUARANTEED ELECTRIC LOANS Operational Controls § 1717.604 Long-range engineering plans and construction work plans. (a) All borrowers are required to maintain up-to-date long-range engineering plans and...

7 CFR 1717.604 - Long-range engineering plans and construction work plans.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 11 2013-01-01 2013-01-01 false Long-range engineering plans and construction work... AND GUARANTEED ELECTRIC LOANS Operational Controls § 1717.604 Long-range engineering plans and construction work plans. (a) All borrowers are required to maintain up-to-date long-range engineering plans and...

7 CFR 1717.604 - Long-range engineering plans and construction work plans.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 11 2014-01-01 2014-01-01 false Long-range engineering plans and construction work... AND GUARANTEED ELECTRIC LOANS Operational Controls § 1717.604 Long-range engineering plans and construction work plans. (a) All borrowers are required to maintain up-to-date long-range engineering plans and...

7 CFR 1717.604 - Long-range engineering plans and construction work plans.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 11 2012-01-01 2012-01-01 false Long-range engineering plans and construction work... AND GUARANTEED ELECTRIC LOANS Operational Controls § 1717.604 Long-range engineering plans and construction work plans. (a) All borrowers are required to maintain up-to-date long-range engineering plans and...

7 CFR 1717.604 - Long-range engineering plans and construction work plans.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 11 2011-01-01 2011-01-01 false Long-range engineering plans and construction work... AND GUARANTEED ELECTRIC LOANS Operational Controls § 1717.604 Long-range engineering plans and construction work plans. (a) All borrowers are required to maintain up-to-date long-range engineering plans and...

Transplantation of Tissue-Engineered Cartilage in an Animal Model (Xenograft and Autograft): Construct Validation.

PubMed

Nemoto, Hitoshi; Watson, Deborah; Masuda, Koichi

2015-01-01

Tissue engineering holds great promise for cartilage repair with minimal donor-site morbidity. The in vivo maturation of a tissue-engineered construct can be tested in the subcutaneous tissues of the same species for autografts or of immunocompromised animals for allografts or xenografts. This section describes detailed protocols for the surgical transplantation of a tissue-engineered construct into an animal model to assess construct validity.

48 CFR 952.236 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Construction and architect-engineer contracts. 952.236 Section 952.236 Federal Acquisition Regulations System DEPARTMENT OF ENERGY... Construction and architect-engineer contracts. ...

48 CFR 952.236 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Construction and architect-engineer contracts. 952.236 Section 952.236 Federal Acquisition Regulations System DEPARTMENT OF ENERGY... Construction and architect-engineer contracts. ...

48 CFR 952.236 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Construction and architect-engineer contracts. 952.236 Section 952.236 Federal Acquisition Regulations System DEPARTMENT OF ENERGY... Construction and architect-engineer contracts. ...

48 CFR 952.236 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Construction and architect-engineer contracts. 952.236 Section 952.236 Federal Acquisition Regulations System DEPARTMENT OF ENERGY... Construction and architect-engineer contracts. ...

48 CFR 952.236 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Construction and architect-engineer contracts. 952.236 Section 952.236 Federal Acquisition Regulations System DEPARTMENT OF ENERGY... Construction and architect-engineer contracts. ...

14 CFR 33.31 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-01-01

... STANDARDS: AIRCRAFT ENGINES Design and Construction; Reciprocating Aircraft Engines § 33.31 Applicability. This subpart prescribes additional design and construction requirements for reciprocating aircraft engines. ...

14 CFR 33.31 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-01-01

... STANDARDS: AIRCRAFT ENGINES Design and Construction; Reciprocating Aircraft Engines § 33.31 Applicability. This subpart prescribes additional design and construction requirements for reciprocating aircraft engines. ...

14 CFR 33.61 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-01-01

... STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.61 Applicability. This subpart prescribes additional design and construction requirements for turbine aircraft engines. ...

14 CFR 33.61 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-01-01

... STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.61 Applicability. This subpart prescribes additional design and construction requirements for turbine aircraft engines. ...

14 CFR 33.61 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-01-01

... STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.61 Applicability. This subpart prescribes additional design and construction requirements for turbine aircraft engines. ...

77 FR 3070 - Electric Engineering, Architectural Services, Design Policies and Construction Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-23

... Engineering, Architectural Services, Design Policies and Construction Standards AGENCY: Rural Utilities..., engineering services and architectural services for transactions above the established threshold dollar levels... Code of Federal Regulations as follows: PART 1724--ELECTRIC ENGINEERING, ARCHITECTURAL SERVICES AND...

The 300 H.P. Benz Aircraft Engine

NASA Technical Reports Server (NTRS)

Heller, A

1921-01-01

A description is given of the Benz 12-cylinder aircraft engine. The 300 H.P. engine, with the cylinders placed at an angle of 60 degrees not only realizes a long-cherished conception, but has received refinement in detail. It may be described as a perfect example of modern German aircraft engine construction. Here, a detailed description is given of the construction of this engine. Emphasis is placed on the design and construction of the cylinders, pistons, and connecting rods. Also discussed are engine fitting, lubrication, oil pumps, bearings, the oil tank, fuel pump, carburetors, and cooling system.

Computational model-informed design and bioprinting of cell-patterned constructs for bone tissue engineering.

PubMed

Carlier, Aurélie; Skvortsov, Gözde Akdeniz; Hafezi, Forough; Ferraris, Eleonora; Patterson, Jennifer; Koç, Bahattin; Van Oosterwyck, Hans

2016-05-17

Three-dimensional (3D) bioprinting is a rapidly advancing tissue engineering technology that holds great promise for the regeneration of several tissues, including bone. However, to generate a successful 3D bone tissue engineering construct, additional complexities should be taken into account such as nutrient and oxygen delivery, which is often insufficient after implantation in large bone defects. We propose that a well-designed tissue engineering construct, that is, an implant with a specific spatial pattern of cells in a matrix, will improve the healing outcome. By using a computational model of bone regeneration we show that particular cell patterns in tissue engineering constructs are able to enhance bone regeneration compared to uniform ones. We successfully bioprinted one of the most promising cell-gradient patterns by using cell-laden hydrogels with varying cell densities and observed a high cell viability for three days following the bioprinting process. In summary, we present a novel strategy for the biofabrication of bone tissue engineering constructs by designing cell-gradient patterns based on a computational model of bone regeneration, and successfully bioprinting the chosen design. This integrated approach may increase the success rate of implanted tissue engineering constructs for critical size bone defects and also can find a wider application in the biofabrication of other types of tissue engineering constructs.

A Knowledge Engineering Approach to Analysis and Evaluation of Construction Schedules

DTIC Science & Technology

1990-02-01

software engineering discipline focusing on constructing KBSs. It is an incremental and cyclical process that requires the interaction of a domain expert(s...the U.S. Army Coips of Engineers ; and (3) the project management software developer, represented by Pinnell Engineering , Inc. Since the primary...the programming skills necessary to convert the raw knowledge intn a form a computer can understand. knowledge engineering : The software engineering

48 CFR 31.105 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

...-engineer contracts. 31.105 Section 31.105 Federal Acquisition Regulations System FEDERAL ACQUISITION... Construction and architect-engineer contracts. (a) This category includes all contracts and contract..., bridges, roads, or other kinds of real property. It also includes architect-engineer contracts related to...

48 CFR 836.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2012 CFR

2012-10-01

... with architect-engineer firms. 836.209 Section 836.209 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER...-engineer firms. (a) When the contracting officer considers it necessary or advantageous to award a contract...

48 CFR 31.105 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

...-engineer contracts. 31.105 Section 31.105 Federal Acquisition Regulations System FEDERAL ACQUISITION... Construction and architect-engineer contracts. (a) This category includes all contracts and contract..., bridges, roads, or other kinds of real property. It also includes architect-engineer contracts related to...

48 CFR 836.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... with architect-engineer firms. 836.209 Section 836.209 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER...-engineer firms. (a) When the contracting officer considers it necessary or advantageous to award a contract...

48 CFR 836.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... with architect-engineer firms. 836.209 Section 836.209 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER...-engineer firms. (a) When the contracting officer considers it necessary or advantageous to award a contract...

48 CFR 31.105 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

...-engineer contracts. 31.105 Section 31.105 Federal Acquisition Regulations System FEDERAL ACQUISITION... Construction and architect-engineer contracts. (a) This category includes all contracts and contract..., bridges, roads, or other kinds of real property. It also includes architect-engineer contracts related to...

48 CFR 36.702 - Forms for use in contracting for architect-engineer services.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contracting for architect-engineer services. 36.702 Section 36.702 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Standard and Optional Forms for Contracting for Construction, Architect-Engineer Services, and...

48 CFR 36.702 - Forms for use in contracting for architect-engineer services.

Code of Federal Regulations, 2011 CFR

2011-10-01

... contracting for architect-engineer services. 36.702 Section 36.702 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Standard and Optional Forms for Contracting for Construction, Architect-Engineer Services, and...

48 CFR 31.105 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

...-engineer contracts. 31.105 Section 31.105 Federal Acquisition Regulations System FEDERAL ACQUISITION... Construction and architect-engineer contracts. (a) This category includes all contracts and contract..., bridges, roads, or other kinds of real property. It also includes architect-engineer contracts related to...

48 CFR 836.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2014 CFR

2014-10-01

... with architect-engineer firms. 836.209 Section 836.209 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER...-engineer firms. (a) When the contracting officer considers it necessary or advantageous to award a contract...

48 CFR 836.209 - Construction contracts with architect-engineer firms.

Code of Federal Regulations, 2013 CFR

2013-10-01

... with architect-engineer firms. 836.209 Section 836.209 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER...-engineer firms. (a) When the contracting officer considers it necessary or advantageous to award a contract...

48 CFR 36.702 - Forms for use in contracting for architect-engineer services.

Code of Federal Regulations, 2014 CFR

2014-10-01

... contracting for architect-engineer services. 36.702 Section 36.702 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Standard and Optional Forms for Contracting for Construction, Architect-Engineer Services, and...

Engineered phages for electronics.

PubMed

Cui, Yue

2016-11-15

Phages are traditionally widely studied in biology and chemistry. In recent years, engineered phages have attracted significant attentions for functionalization or construction of electronic devices, due to their specific binding, catalytic, nucleating or electronic properties. To apply the engineered phages in electronics, these are a number of interesting questions: how to engineer phages for electronics? How are the engineered phages characterized? How to assemble materials with engineered phages? How are the engineered phages micro or nanopatterned? What are the strategies to construct electronics devices with engineered phages? This review will highlight the early attempts to address these questions and explore the fundamental and practical aspects of engineered phages in electronics, including the approaches for selection or expression of specific peptides on phage coat proteins, characterization of engineered phages in electronics, assembly of electronic materials, patterning of engineered phages, and construction of electronic devices. It provides the methodologies and opens up ex-cit-ing op-por-tu-ni-ties for the development of a variety of new electronic materials and devices based on engineered phages for future applications. Copyright © 2016 Elsevier B.V. All rights reserved.

78 FR 77334 - Small Business Size Standards: Construction

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-23

... Dredging and Surface Cleanup Activities, an ``exception'' under Other Heavy and Civil Engineering... ``exception'' under Other Heavy and Civil Engineering Construction (NAICS 238910), from $20 million to $30... exception under Other Heavy and Civil Engineering Construction (NAICS 238910) and retain the current size...

Economic Impact Forecast System (EIFS). Version 2.0. Users Manual. Supplement II. European Economic Impact Forecast System (EEIFS), Phase 1, (FRG/EIFS Pilot Model).

DTIC Science & Technology

1982-05-01

Chmpip. tL : Construction engineering Research Laboratory ; available from NTIS. 1982. 71 p. (Technical report / Construction Engineering Researsh ...AD-Al17 661 CONSTRUCTION ENGINEERING RESEARCH LAB (ARMY) CHAMPAIGN IL F/G 5/3 ECONOMIC IMPACT FORECAST SYSTEM (EIFS). VERSION 2.0. USERS MANU--ETC(u...CONSTRUCTION ENGINEERING RESEARCH LABORATORY 4A762720A896-C-004 P.O. BOX 4005, CHAMPAIGN, IL 61820 I. CONTROLLING OFFICE NAME AND ADDRESS It. REPORT

Technician Career Opportunities in Engineering Technology.

ERIC Educational Resources Information Center

Engineers' Council for Professional Development, New York, NY.

Career opportunities for engineering technicians are available in the technologies relating to air conditioning, heating, and refrigeration, aviation and aerospace, building construction, chemical engineering, civil engineering, electrical engineering, electronics, industrial engineering, instrumentation, internal combustion engines, mechanical…

22 CFR 228.39 - Special source rules for construction and engineering services.

Code of Federal Regulations, 2010 CFR

2010-04-01

... engineering services. 228.39 Section 228.39 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES ON... engineering services. Advanced developing countries, eligible under Geographic Code 941, which have attained a competitive capability in international markets for construction services or engineering services are not...

7 CFR 1717.606 - Standard forms of construction contracts, and engineering and architectural services contracts.

Code of Federal Regulations, 2013 CFR

2013-01-01

... engineering and architectural services contracts. 1717.606 Section 1717.606 Agriculture Regulations of the... Standard forms of construction contracts, and engineering and architectural services contracts. All..., materials, equipment, engineering services, and architectural services, regardless of the source of funding...

7 CFR 1717.606 - Standard forms of construction contracts, and engineering and architectural services contracts.

Code of Federal Regulations, 2012 CFR

2012-01-01

... engineering and architectural services contracts. 1717.606 Section 1717.606 Agriculture Regulations of the... Standard forms of construction contracts, and engineering and architectural services contracts. All..., materials, equipment, engineering services, and architectural services, regardless of the source of funding...

7 CFR 1717.606 - Standard forms of construction contracts, and engineering and architectural services contracts.

Code of Federal Regulations, 2011 CFR

2011-01-01

... engineering and architectural services contracts. 1717.606 Section 1717.606 Agriculture Regulations of the... Standard forms of construction contracts, and engineering and architectural services contracts. All..., materials, equipment, engineering services, and architectural services, regardless of the source of funding...

7 CFR 1717.606 - Standard forms of construction contracts, and engineering and architectural services contracts.

Code of Federal Regulations, 2014 CFR

2014-01-01

... engineering and architectural services contracts. 1717.606 Section 1717.606 Agriculture Regulations of the... Standard forms of construction contracts, and engineering and architectural services contracts. All..., materials, equipment, engineering services, and architectural services, regardless of the source of funding...

7 CFR 1717.606 - Standard forms of construction contracts, and engineering and architectural services contracts.

Code of Federal Regulations, 2010 CFR

2010-01-01

... engineering and architectural services contracts. 1717.606 Section 1717.606 Agriculture Regulations of the... Standard forms of construction contracts, and engineering and architectural services contracts. All..., materials, equipment, engineering services, and architectural services, regardless of the source of funding...

22 CFR 228.39 - Special source rules for construction and engineering services.

Code of Federal Regulations, 2011 CFR

2011-04-01

... engineering services. 228.39 Section 228.39 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES ON... engineering services. Advanced developing countries, eligible under Geographic Code 941, which have attained a competitive capability in international markets for construction services or engineering services are not...

Construction Strategy and Progress of Whole Intervertebral Disc Tissue Engineering.

PubMed

Yang, Qiang; Xu, Hai-wei; Hurday, Sookesh; Xu, Bao-shan

2016-02-01

Degenerative disc disease (DDD) is the major cause of low back pain, which usually leads to work absenteeism, medical visits and hospitalization. Because the current conservative procedures and surgical approaches to treatment of DDD only aim to relieve the symptoms of disease but not to regenerate the diseased disc, their long-term efficiency is limited. With the rapid developments in medical science, tissue engineering techniques have progressed markedly in recent years, providing a novel regenerative strategy for managing intervertebral disc disease. However, there are as yet no ideal methods for constructing tissue-engineered intervertebral discs. This paper reviews published reports pertaining to intervertebral disc tissue engineering and summarizes data concerning the seed cells and scaffold materials for tissue-engineered intervertebral discs, construction of tissue-engineered whole intervertebral discs, relevant animal experiments and effects of mechanics on the construction of tissue-engineered intervertebral disc and outlines the existing problems and future directions. Although the perfect regenerative strategy for treating DDD has not yet been developed, great progress has been achieved in the construction of tissue-engineered intervertebral discs. It is believed that ongoing research on intervertebral disc tissue engineering will result in revolutionary progress in the treatment of DDD. © 2016 Chinese Orthopaedic Association and John Wiley & Sons Australia, Ltd.

48 CFR 853.236 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Construction and architect-engineer contracts. 853.236 Section 853.236 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS CLAUSES AND FORMS FORMS Prescription of Forms 853.236 Construction and architect-engineer...

48 CFR 853.236 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Construction and architect-engineer contracts. 853.236 Section 853.236 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS CLAUSES AND FORMS FORMS Prescription of Forms 853.236 Construction and architect-engineer...

48 CFR 853.236 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Construction and architect-engineer contracts. 853.236 Section 853.236 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS CLAUSES AND FORMS FORMS Prescription of Forms 853.236 Construction and architect-engineer...

48 CFR 853.236 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Construction and architect-engineer contracts. 853.236 Section 853.236 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS CLAUSES AND FORMS FORMS Prescription of Forms 853.236 Construction and architect-engineer...

48 CFR 853.236 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Construction and architect-engineer contracts. 853.236 Section 853.236 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS CLAUSES AND FORMS FORMS Prescription of Forms 853.236 Construction and architect-engineer...

Popularizing Geological Education among Civil Engineering Students

ERIC Educational Resources Information Center

Chen, Xiang-jun; Zhou, Ying

2012-01-01

The sustainable development of an economy and a society cannot be realized without the help of modern geoscience. Engineering geology knowledge is necessary on a civil engineering construction site to ensure the construction work goes smoothly. This paper first discusses the importance of geoscience, especially the study of engineering geology.…

76 FR 28333 - Electric Engineering, Architectural Services, Design Policies and Construction Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-17

... CFR Parts 1724 and 1726 RIN 0572-AC20 Electric Engineering, Architectural Services, Design Policies... standard forms of contracts promulgated by RUS for construction, procurement, engineering services and... XVII of title 7 of the Code of Federal Regulations as follows: PART 1724--ELECTRIC ENGINEERING...

30 CFR 36.25 - Engine exhaust system.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Engine exhaust system. 36.25 Section 36.25... EQUIPMENT Construction and Design Requirements § 36.25 Engine exhaust system. (a) Construction. The exhaust system of the engine shall be designed to withstand an internal pressure equal to 4 times the maximum...

Evaluation of Hybrid Learning in a Construction Engineering Context: A Mixed-Method Approach

ERIC Educational Resources Information Center

Karabulut-Ilgu, Aliye; Jahren, Charles

2016-01-01

Engineering educators call for a widespread implementation of hybrid learning to respond to rapidly changing demands of the 21st century. In response to this call, a junior-level course in the Construction Engineering program entitled Construction Equipment and Heavy Construction Methods was converted into a hybrid learning model. The overarching…

Construction and engineering of large biochemical pathways via DNA assembler

PubMed Central

Shao, Zengyi; Zhao, Huimin

2015-01-01

Summary DNA assembler enables rapid construction and engineering of biochemical pathways in a one-step fashion by exploitation of the in vivo homologous recombination mechanism in Saccharomyces cerevisiae. It has many applications in pathway engineering, metabolic engineering, combinatorial biology, and synthetic biology. Here we use two examples including the zeaxanthin biosynthetic pathway and the aureothin biosynthetic gene cluster to describe the key steps in the construction of pathways containing multiple genes using the DNA assembler approach. Methods for construct design, pathway assembly, pathway confirmation, and functional analysis are shown. The protocol for fine genetic modifications such as site-directed mutagenesis for engineering the aureothin gene cluster is also illustrated. PMID:23996442

14 CFR 33.61 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.61 Applicability. This subpart prescribes additional design and construction requirements for turbine aircraft engines. ...

14 CFR 33.61 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.61 Applicability. This subpart prescribes additional design and construction requirements for turbine aircraft engines. ...

48 CFR 53.236 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Construction and architect-engineer contracts. 53.236 Section 53.236 Federal Acquisition Regulations System FEDERAL ACQUISITION...-engineer contracts. ...

48 CFR 53.236 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Construction and architect-engineer contracts. 53.236 Section 53.236 Federal Acquisition Regulations System FEDERAL ACQUISITION...-engineer contracts. ...

48 CFR 53.236 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Construction and architect-engineer contracts. 53.236 Section 53.236 Federal Acquisition Regulations System FEDERAL ACQUISITION...-engineer contracts. ...

48 CFR 53.236 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Construction and architect-engineer contracts. 53.236 Section 53.236 Federal Acquisition Regulations System FEDERAL ACQUISITION...-engineer contracts. ...

48 CFR 53.236 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Construction and architect-engineer contracts. 53.236 Section 53.236 Federal Acquisition Regulations System FEDERAL ACQUISITION...-engineer contracts. ...

Mountain Plains Learning Experience Guide: Automotive Repair. Course: Engine Repair.

ERIC Educational Resources Information Center

Schramm, C.; Osland, Walt

One of twelve individualized courses included in an automotive repair curriculum, this course covers theory and construction, inspection diagnoses, and service and overhaul of automotive engines. The course is comprised of five units: (1) Fundamentals of Four-Cycle Engines, (2) Engine Construction, (3) Valve Train, (4) Lubricating Systems, and (5)…

Engineer at Lehigh University Campaigns for More Construction Research.

ERIC Educational Resources Information Center

Wheeler, David L.

1987-01-01

A civil engineering professor would like to see civil engineers spend less time looking at broken structures and more time testing construction materials, and has founded a research center for that purpose. (MSE)

Constructing an Efficient Self-Tuning Aircraft Engine Model for Control and Health Management Applications

NASA Technical Reports Server (NTRS)

Armstrong, Jeffrey B.; Simon, Donald L.

2012-01-01

Self-tuning aircraft engine models can be applied for control and health management applications. The self-tuning feature of these models minimizes the mismatch between any given engine and the underlying engineering model describing an engine family. This paper provides details of the construction of a self-tuning engine model centered on a piecewise linear Kalman filter design. Starting from a nonlinear transient aerothermal model, a piecewise linear representation is first extracted. The linearization procedure creates a database of trim vectors and state-space matrices that are subsequently scheduled for interpolation based on engine operating point. A series of steady-state Kalman gains can next be constructed from a reduced-order form of the piecewise linear model. Reduction of the piecewise linear model to an observable dimension with respect to available sensed engine measurements can be achieved using either a subset or an optimal linear combination of "health" parameters, which describe engine performance. The resulting piecewise linear Kalman filter is then implemented for faster-than-real-time processing of sensed engine measurements, generating outputs appropriate for trending engine performance, estimating both measured and unmeasured parameters for control purposes, and performing on-board gas-path fault diagnostics. Computational efficiency is achieved by designing multidimensional interpolation algorithms that exploit the shared scheduling of multiple trim vectors and system matrices. An example application illustrates the accuracy of a self-tuning piecewise linear Kalman filter model when applied to a nonlinear turbofan engine simulation. Additional discussions focus on the issue of transient response accuracy and the advantages of a piecewise linear Kalman filter in the context of validation and verification. The techniques described provide a framework for constructing efficient self-tuning aircraft engine models from complex nonlinear simulations.Self-tuning aircraft engine models can be applied for control and health management applications. The self-tuning feature of these models minimizes the mismatch between any given engine and the underlying engineering model describing an engine family. This paper provides details of the construction of a self-tuning engine model centered on a piecewise linear Kalman filter design. Starting from a nonlinear transient aerothermal model, a piecewise linear representation is first extracted. The linearization procedure creates a database of trim vectors and state-space matrices that are subsequently scheduled for interpolation based on engine operating point. A series of steady-state Kalman gains can next be constructed from a reduced-order form of the piecewise linear model. Reduction of the piecewise linear model to an observable dimension with respect to available sensed engine measurements can be achieved using either a subset or an optimal linear combination of "health" parameters, which describe engine performance. The resulting piecewise linear Kalman filter is then implemented for faster-than-real-time processing of sensed engine measurements, generating outputs appropriate for trending engine performance, estimating both measured and unmeasured parameters for control purposes, and performing on-board gas-path fault diagnostics. Computational efficiency is achieved by designing multidimensional interpolation algorithms that exploit the shared scheduling of multiple trim vectors and system matrices. An example application illustrates the accuracy of a self-tuning piecewise linear Kalman filter model when applied to a nonlinear turbofan engine simulation. Additional discussions focus on the issue of transient response accuracy and the advantages of a piecewise linear Kalman filter in the context of validation and verification. The techniques described provide a framework for constructing efficient self-tuning aircraft engine models from complex nonlinear simulatns.

An Evaluation of the Pavement Condition Index Prediction Model for Rigid Airfield Pavements

DTIC Science & Technology

1982-09-01

UNCLASSIFIED SECURITY CLASSIFICATION OF THIS PAGO(I*%A Data Entotoi) The United States Army Corps of Engineers, Construction Engineering Research Laboratory...Condition . . . 31 Pavement Design/ Construction ....... . 82 Aircraft Traffic ........ .............. 82 Climate Conditions ........ ............. 84...PATTERSON AFB . . . . . . . . . . . . . . . . . . . . . . . . . 155 C. DATA OBTAINED FROM THE CONSTRUCTION ENGINEERING RESEARCH LABORATORY. .. .. 168 D

48 CFR 1827.304-3 - Contracts for construction work or architect-engineer services. (NASA supplements paragraph (a))

Code of Federal Regulations, 2010 CFR

2010-10-01

... work or architect-engineer services. (NASA supplements paragraph (a)) 1827.304-3 Section 1827.304-3... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 1827.304-3 Contracts for construction work or architect-engineer services. (NASA supplements paragraph (a)) (a) For construction or...

Image-guided tissue engineering

PubMed Central

Ballyns, Jeffrey J; Bonassar, Lawrence J

2009-01-01

Replication of anatomic shape is a significant challenge in developing implants for regenerative medicine. This has lead to significant interest in using medical imaging techniques such as magnetic resonance imaging and computed tomography to design tissue engineered constructs. Implementation of medical imaging and computer aided design in combination with technologies for rapid prototyping of living implants enables the generation of highly reproducible constructs with spatial resolution up to 25 μm. In this paper, we review the medical imaging modalities available and a paradigm for choosing a particular imaging technique. We also present fabrication techniques and methodologies for producing cellular engineered constructs. Finally, we comment on future challenges involved with image guided tissue engineering and efforts to generate engineered constructs ready for implantation. PMID:19583811

A puzzle assembly strategy for fabrication of large engineered cartilage tissue constructs.

PubMed

Nover, Adam B; Jones, Brian K; Yu, William T; Donovan, Daniel S; Podolnick, Jeremy D; Cook, James L; Ateshian, Gerard A; Hung, Clark T

2016-03-21

Engineering of large articular cartilage tissue constructs remains a challenge as tissue growth is limited by nutrient diffusion. Here, a novel strategy is investigated, generating large constructs through the assembly of individually cultured, interlocking, smaller puzzle-shaped subunits. These constructs can be engineered consistently with more desirable mechanical and biochemical properties than larger constructs (~4-fold greater Young׳s modulus). A failure testing technique was developed to evaluate the physiologic functionality of constructs, which were cultured as individual subunits for 28 days, then assembled and cultured for an additional 21-35 days. Assembled puzzle constructs withstood large deformations (40-50% compressive strain) prior to failure. Their ability to withstand physiologic loads may be enhanced by increases in subunit strength and assembled culture time. A nude mouse model was utilized to show biocompatibility and fusion of assembled puzzle pieces in vivo. Overall, the technique offers a novel, effective approach to scaling up engineered tissues and may be combined with other techniques and/or applied to the engineering of other tissues. Future studies will aim to optimize this system in an effort to engineer and integrate robust subunits to fill large defects. Copyright © 2016 Elsevier Ltd. All rights reserved.

A Puzzle Assembly Strategy for Fabrication of Large Engineered Cartilage Tissue Constructs

PubMed Central

Nover, Adam B.; Jones, Brian K.; Yu, William T.; Donovan, Daniel S.; Podolnick, Jeremy D.; Cook, James L.; Ateshian, Gerard A.; Hung, Clark T.

2016-01-01

Engineering of large articular cartilage tissue constructs remains a challenge as tissue growth is limited by nutrient diffusion. Here, a novel strategy is investigated, generating large constructs through the assembly of individually cultured, interlocking, smaller puzzle-shaped subunits. These constructs can be engineered consistently with more desirable mechanical and biochemical properties than larger constructs (~4-fold greater Young's modulus). A failure testing technique was developed to evaluate the physiologic functionality of constructs, which were cultured as individual subunits for 28 days, then assembled and cultured for an additional 21-35 days. Assembled puzzle constructs withstood large deformations (40-50% compressive strain) prior to failure. Their ability to withstand physiologic loads may be enhanced by increases in subunit strength and assembled culture time. A nude mouse model was utilized to show biocompatibility and fusion of assembled puzzle pieces in vivo. Overall, the technique offers a novel, effective approach to scaling up engineered tissues and may be combined with other techniques and/or applied to the engineering of other tissues. Future studies will aim to optimize this system in an effort to engineer and integrate robust subunits to fill large defects. PMID:26895780

Engineering a lunar photolithoautotroph to thrive on the moon - life or simulacrum?

NASA Astrophysics Data System (ADS)

Ellery, A. A.

2018-07-01

Recent work in developing self-replicating machines has approached the problem as an engineering problem, using engineering materials and methods to implement an engineering analogue of a hitherto uniquely biological function. The question is - can anything be learned that might be relevant to an astrobiological context in which the problem is to determine the general form of biology independent of the Earth. Compared with other non-terrestrial biology disciplines, engineered life is more demanding. Engineering a self-replicating machine tackles real environments unlike artificial life which avoids the problem of physical instantiation altogether by examining software models. Engineering a self-replicating machine is also more demanding than synthetic biology as no library of functional components exists. Everything must be constructed de novo. Biological systems already have the capacity to self-replicate but no engineered machine has yet been constructed with the same ability - this is our primary goal. On the basis of the von Neumann analysis of self-replication, self-replication is a by-product of universal construction capability - a universal constructor is a machine that can construct anything (in a functional sense) given the appropriate instructions (DNA/RNA), energy (ATP) and materials (food). In the biological cell, the universal construction mechanism is the ribosome. The ribosome is a biological assembly line for constructing proteins while DNA constitutes a design specification. For a photoautotroph, the energy source is ambient and the food is inorganic. We submit that engineering a self-replicating machine opens up new areas of astrobiology to be explored in the limits of life.

7 CFR 1753.15 - General.

Code of Federal Regulations, 2012 CFR

2012-01-01

... funds, postloan architectural or engineering services shall be obtained if (1) the construction cost... TELECOMMUNICATIONS SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Engineering Services § 1753.15 General. (a)(1) The standard RUS loan documents contain provisions regarding engineering and architectural services performed...

7 CFR 1753.15 - General.

Code of Federal Regulations, 2011 CFR

2011-01-01

... funds, postloan architectural or engineering services shall be obtained if (1) the construction cost... TELECOMMUNICATIONS SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Engineering Services § 1753.15 General. (a)(1) The standard RUS loan documents contain provisions regarding engineering and architectural services performed...

7 CFR 1753.15 - General.

Code of Federal Regulations, 2014 CFR

2014-01-01

... funds, postloan architectural or engineering services shall be obtained if (1) the construction cost... TELECOMMUNICATIONS SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Engineering Services § 1753.15 General. (a)(1) The standard RUS loan documents contain provisions regarding engineering and architectural services performed...

7 CFR 1753.15 - General.

Code of Federal Regulations, 2010 CFR

2010-01-01

... funds, postloan architectural or engineering services shall be obtained if (1) the construction cost... TELECOMMUNICATIONS SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Engineering Services § 1753.15 General. (a)(1) The standard RUS loan documents contain provisions regarding engineering and architectural services performed...

7 CFR 1753.15 - General.

Code of Federal Regulations, 2013 CFR

2013-01-01

... funds, postloan architectural or engineering services shall be obtained if (1) the construction cost... TELECOMMUNICATIONS SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Engineering Services § 1753.15 General. (a)(1) The standard RUS loan documents contain provisions regarding engineering and architectural services performed...

Morphological changes in paraurethral area after introduction of tissue engineering construct on the basis of adipose tissue stromal cells.

PubMed

Makarov, A V; Arutyunyan, I V; Bol'shakova, G B; Volkov, A V; Gol'dshtein, D V

2009-10-01

We studied morphological changes in the paraurethral area of Wistar rats after introduction of tissue engineering constructs on the basis of multipotent mesenchymal stem cells and gelatin sponge. The tissue engineering construct containing autologous culture of the stromal fraction of the adipose tissue was most effective. After introduction of this construct we observed more rapid degradation of the construct matrix and more intensive formation of collagen fibers.

Making Work: Demonstrating Thermodynamic Concepts with Solar-Powered Wax and Rubber Heat Engines

ERIC Educational Resources Information Center

Appleyard, S. J.

2007-01-01

Construction details are provided for simple heat engines that use candle wax and elastomers as working substances. The engines are constructed using common household materials and can be easily constructed in a school classroom or at home. They work reliably and are useful tools for demonstrating the conversion of heat to mechanical work. They…

49 CFR 268.21 - Down-selection of one or more Maglev projects for further study and selection of one project for...

Code of Federal Regulations, 2014 CFR

2014-10-01

... further study and selection of one project for final design, engineering, and construction funding. 268.21... and selection of one project for final design, engineering, and construction funding. (a) Upon... analyses necessary prior to initiation of construction. Final design and engineering work will also be...

49 CFR 268.21 - Down-selection of one or more Maglev projects for further study and selection of one project for...

Code of Federal Regulations, 2010 CFR

2010-10-01

... further study and selection of one project for final design, engineering, and construction funding. 268.21... and selection of one project for final design, engineering, and construction funding. (a) Upon... analyses necessary prior to initiation of construction. Final design and engineering work will also be...

49 CFR 268.21 - Down-selection of one or more Maglev projects for further study and selection of one project for...

Code of Federal Regulations, 2011 CFR

2011-10-01

... further study and selection of one project for final design, engineering, and construction funding. 268.21... and selection of one project for final design, engineering, and construction funding. (a) Upon... analyses necessary prior to initiation of construction. Final design and engineering work will also be...

49 CFR 268.21 - Down-selection of one or more Maglev projects for further study and selection of one project for...

Code of Federal Regulations, 2012 CFR

2012-10-01

... further study and selection of one project for final design, engineering, and construction funding. 268.21... and selection of one project for final design, engineering, and construction funding. (a) Upon... analyses necessary prior to initiation of construction. Final design and engineering work will also be...

49 CFR 268.21 - Down-selection of one or more Maglev projects for further study and selection of one project for...

Code of Federal Regulations, 2013 CFR

2013-10-01

... further study and selection of one project for final design, engineering, and construction funding. 268.21... and selection of one project for final design, engineering, and construction funding. (a) Upon... analyses necessary prior to initiation of construction. Final design and engineering work will also be...

Building information modelling review with potential applications in tunnel engineering of China.

PubMed

Zhou, Weihong; Qin, Haiyang; Qiu, Junling; Fan, Haobo; Lai, Jinxing; Wang, Ke; Wang, Lixin

2017-08-01

Building information modelling (BIM) can be applied to tunnel engineering to address a number of problems, including complex structure, extensive design, long construction cycle and increased security risks. To promote the development of tunnel engineering in China, this paper combines actual cases, including the Xingu mountain tunnel and the Shigu Mountain tunnel, to systematically analyse BIM applications in tunnel engineering in China. The results indicate that BIM technology in tunnel engineering is currently mainly applied during the design stage rather than during construction and operation stages. The application of BIM technology in tunnel engineering covers many problems, such as a lack of standards, incompatibility of different software, disorganized management, complex combination with GIS (Geographic Information System), low utilization rate and poor awareness. In this study, through summary of related research results and engineering cases, suggestions are introduced and an outlook for the BIM application in tunnel engineering in China is presented, which provides guidance for design optimization, construction standards and later operation maintenance.

Building information modelling review with potential applications in tunnel engineering of China

PubMed Central

Zhou, Weihong; Qin, Haiyang; Fan, Haobo; Lai, Jinxing; Wang, Ke; Wang, Lixin

2017-01-01

Building information modelling (BIM) can be applied to tunnel engineering to address a number of problems, including complex structure, extensive design, long construction cycle and increased security risks. To promote the development of tunnel engineering in China, this paper combines actual cases, including the Xingu mountain tunnel and the Shigu Mountain tunnel, to systematically analyse BIM applications in tunnel engineering in China. The results indicate that BIM technology in tunnel engineering is currently mainly applied during the design stage rather than during construction and operation stages. The application of BIM technology in tunnel engineering covers many problems, such as a lack of standards, incompatibility of different software, disorganized management, complex combination with GIS (Geographic Information System), low utilization rate and poor awareness. In this study, through summary of related research results and engineering cases, suggestions are introduced and an outlook for the BIM application in tunnel engineering in China is presented, which provides guidance for design optimization, construction standards and later operation maintenance. PMID:28878970

Building information modelling review with potential applications in tunnel engineering of China

NASA Astrophysics Data System (ADS)

Zhou, Weihong; Qin, Haiyang; Qiu, Junling; Fan, Haobo; Lai, Jinxing; Wang, Ke; Wang, Lixin

2017-08-01

Building information modelling (BIM) can be applied to tunnel engineering to address a number of problems, including complex structure, extensive design, long construction cycle and increased security risks. To promote the development of tunnel engineering in China, this paper combines actual cases, including the Xingu mountain tunnel and the Shigu Mountain tunnel, to systematically analyse BIM applications in tunnel engineering in China. The results indicate that BIM technology in tunnel engineering is currently mainly applied during the design stage rather than during construction and operation stages. The application of BIM technology in tunnel engineering covers many problems, such as a lack of standards, incompatibility of different software, disorganized management, complex combination with GIS (Geographic Information System), low utilization rate and poor awareness. In this study, through summary of related research results and engineering cases, suggestions are introduced and an outlook for the BIM application in tunnel engineering in China is presented, which provides guidance for design optimization, construction standards and later operation maintenance.

23 CFR 661.3 - Who must comply with this regulation?

Code of Federal Regulations, 2013 CFR

2013-04-01

... authorities must comply to participate in the IRRBP by applying for preliminary engineering (PE), construction, and construction engineering (CE) activities for the replacement or rehabilitation of structurally....3 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC...

23 CFR 661.3 - Who must comply with this regulation?

Code of Federal Regulations, 2010 CFR

2010-04-01

... authorities must comply to participate in the IRRBP by applying for preliminary engineering (PE), construction, and construction engineering (CE) activities for the replacement or rehabilitation of structurally....3 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC...

23 CFR 661.3 - Who must comply with this regulation?

Code of Federal Regulations, 2012 CFR

2012-04-01

... authorities must comply to participate in the IRRBP by applying for preliminary engineering (PE), construction, and construction engineering (CE) activities for the replacement or rehabilitation of structurally....3 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC...

23 CFR 661.3 - Who must comply with this regulation?

Code of Federal Regulations, 2011 CFR

2011-04-01

... authorities must comply to participate in the IRRBP by applying for preliminary engineering (PE), construction, and construction engineering (CE) activities for the replacement or rehabilitation of structurally....3 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC...

23 CFR 661.3 - Who must comply with this regulation?

Code of Federal Regulations, 2014 CFR

2014-04-01

... authorities must comply to participate in the IRRBP by applying for preliminary engineering (PE), construction, and construction engineering (CE) activities for the replacement or rehabilitation of structurally....3 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC...

Savannah River Plant engineering, design, and construction history of ``S`` projects and other work, January 1961--December 1964. Volume 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1970-03-01

The work described in this volume of ``S`` Projects History is an extension of the type of work described in Volume I. E.I. du Pont de flemours & Company had entered into Contract AT (07-2)-l with the United States Atomic Energy Commission to develop, design, construct, install, and operate facilities to produce heavy water, fissionable materials, and related products. Under this contract,, Du Pont constructed and operated the Savannah River Plant. The engineering, design, and construction for most of the larger ``S`` projects was performed by the Engineering DeDartment. For some of the large and many of the smaller projectsmore » the Engineering Department was responsible only for the construction because the Atomic Energy Division (AED) of the Explosives Department handled the other phases. The Engineering Department Costruction Division also performed the physical work for many of the plant work orders. This volume includes a general description of the Du Pont Engineering Department activities pertaining to the engineering, design, and construction of the ``S`` projects at the Savannah River Plant; brief summaries of the projects and principal work requests; and supplementary informaticn on a few subjects in Volume I for which final data was not available at the closing date. Projects and other plant engineering work which were handled entirely by the Explosives Department -- AED are not included in this history.« less

Towards organ printing: engineering an intra-organ branched vascular tree.

PubMed

Visconti, Richard P; Kasyanov, Vladimir; Gentile, Carmine; Zhang, Jing; Markwald, Roger R; Mironov, Vladimir

2010-03-01

Effective vascularization of thick three-dimensional engineered tissue constructs is a problem in tissue engineering. As in native organs, a tissue-engineered intra-organ vascular tree must be comprised of a network of hierarchically branched vascular segments. Despite this requirement, current tissue-engineering efforts are still focused predominantly on engineering either large-diameter macrovessels or microvascular networks. We present the emerging concept of organ printing or robotic additive biofabrication of an intra-organ branched vascular tree, based on the ability of vascular tissue spheroids to undergo self-assembly. The feasibility and challenges of this robotic biofabrication approach to intra-organ vascularization for tissue engineering based on organ-printing technology using self-assembling vascular tissue spheroids including clinically relevantly vascular cell sources are analyzed. It is not possible to engineer 3D thick tissue or organ constructs without effective vascularization. An effective intra-organ vascular system cannot be built by the simple connection of large-diameter vessels and microvessels. Successful engineering of functional human organs suitable for surgical implantation will require concomitant engineering of a 'built in' intra-organ branched vascular system. Organ printing enables biofabrication of human organ constructs with a 'built in' intra-organ branched vascular tree.

Mineralization Induction of Gingival Fibroblasts and Construction of a Sandwich Tissue-Engineered Complex for Repairing Periodontal Defects

PubMed Central

Wu, Mingxuan; Zhang, Yanning; Liu, Huijuan; Dong, Fusheng

2018-01-01

Background The ideal healing technique for periodontal tissue defects would involve the functional regeneration of the alveolar bone, cementum, and periodontal ligament, with new periodontal attachment formation. In this study, gingival fibroblasts were induced and a “sandwich” tissue-engineered complex (a tissue-engineered periodontal membrane between 2 tissue-engineered mineralized membranes) was constructed to repair periodontal defects. We evaluated the effects of gingival fibroblasts used as seed cells on the repair of periodontal defects and periodontal regeneration. Material/Methods Primitively cultured gingival fibroblasts were seeded bilaterally on Bio-Gide collagen membrane (a tissue-engineered periodontal membrane) or unilaterally on small intestinal submucosa segments, and their mineralization was induced. A tissue-engineered sandwich was constructed, comprising the tissue-engineered periodontal membrane flanked by 2 mineralized membranes. Periodontal defects in premolar regions of Beagles were repaired using the tissue-engineered sandwich or periodontal membranes. Periodontal reconstruction was compared to normal and trauma controls 10 or 20 days postoperatively. Results Periodontal defects were completely repaired by the sandwich tissue-engineered complex, with intact new alveolar bone and cementum, and a new periodontal ligament, 10 days postoperatively. Conclusions The sandwich tissue-engineered complex can achieve ideal periodontal reconstruction rapidly. PMID:29470454

Industrial Education. "Small Engines".

ERIC Educational Resources Information Center

Parma City School District, OH.

Part of a series of curriculum guides dealing with industrial education in junior high schools, this guide provides the student with information and manipulative experiences on small gasoline engines. Included are sections on shop adjustment, safety, small engines, internal combustion, engine construction, four stroke engines, two stroke engines,…

Nuclear Engineering Technologists in the Nuclear Power Era

ERIC Educational Resources Information Center

Wang, C. H.; And Others

1974-01-01

Describes manpower needs in nuclear engineering in the areas of research and development, architectural engineering and construction supervision, power reactor operations, and regulatory tasks. Outlines a suitable curriculum to prepare students for the tasks related to construction and operation of power reactors. (GS)

The Expanding World of Tissue Engineering: The Building Blocks and New Applications of Tissue Engineered Constructs

PubMed Central

Zorlutuna, Pinar; Vrana, Nihal Engin; Khademhosseini, Ali

2013-01-01

The field of tissue engineering has been growing in the recent years as more products have made it to the market and as new uses for the engineered tissues have emerged, motivating many researchers to engage in this multidisciplinary field of research. Engineered tissues are now not only considered as end products for regenerative medicine, but also have emerged as enabling technologies for other fields of research ranging from drug discovery to biorobotics. This widespread use necessitates a variety of methodologies for production of tissue engineered constructs. In this review, these methods together with their non-clinical applications will be described. First, we will focus on novel materials used in tissue engineering scaffolds; such as recombinant proteins and synthetic, self assembling polypeptides. The recent advances in the modular tissue engineering area will be discussed. Then scaffold-free production methods, based on either cell sheets or cell aggregates will be described. Cell sources used in tissue engineering and new methods that provide improved control over cell behavior such as pathway engineering and biomimetic microenvironments for directing cell differentiation will be discussed. Finally, we will summarize the emerging uses of engineered constructs such as model tissues for drug discovery, cancer research and biorobotics applications. PMID:23268388

Students' Changing Images of Engineering and Engineers. Research Brief

ERIC Educational Resources Information Center

Jocuns, Andrew; Stevens, Reed; Garrison, Lari; Amos, Daniel

2008-01-01

This study analyzes the images of engineers and engineering that students construct over the course of their undergraduate engineering educations. Students in their first year of study to become engineers knew very little about the work they would be doing as an engineer and their expectations were more specific, hopeful, and high status than…

A Method for Search Engine Selection using Thesaurus for Selective Meta-Search Engine

NASA Astrophysics Data System (ADS)

Goto, Shoji; Ozono, Tadachika; Shintani, Toramatsu

In this paper, we propose a new method for selecting search engines on WWW for selective meta-search engine. In selective meta-search engine, a method is needed that would enable selecting appropriate search engines for users' queries. Most existing methods use statistical data such as document frequency. These methods may select inappropriate search engines if a query contains polysemous words. In this paper, we describe an search engine selection method based on thesaurus. In our method, a thesaurus is constructed from documents in a search engine and is used as a source description of the search engine. The form of a particular thesaurus depends on the documents used for its construction. Our method enables search engine selection by considering relationship between terms and overcomes the problems caused by polysemous words. Further, our method does not have a centralized broker maintaining data, such as document frequency for all search engines. As a result, it is easy to add a new search engine, and meta-search engines become more scalable with our method compared to other existing methods.

Study on evaluation of construction reliability for engineering project based on fuzzy language operator

NASA Astrophysics Data System (ADS)

Shi, Yu-Fang; Ma, Yi-Yi; Song, Ping-Ping

2018-03-01

System Reliability Theory is a research hotspot of management science and system engineering in recent years, and construction reliability is useful for quantitative evaluation of project management level. According to reliability theory and target system of engineering project management, the defination of construction reliability appears. Based on fuzzy mathematics theory and language operator, value space of construction reliability is divided into seven fuzzy subsets and correspondingly, seven membership function and fuzzy evaluation intervals are got with the operation of language operator, which provides the basis of corresponding method and parameter for the evaluation of construction reliability. This method is proved to be scientific and reasonable for construction condition and an useful attempt for theory and method research of engineering project system reliability.

SAE 2018-01-1412 Constructing Engine Maps - Presentation at the April 2018 World Congress

EPA Pesticide Factsheets

This presentation describes important factors and approach, along with the process for constructing complete engine maps using engine dynamometer and in-vehicle test data for use in ALPHA or any other full vehicle simulation which performs similar analyses

48 CFR 1536.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer contracts. 1536.602 Section 1536.602 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1536.602 Selection of firms for architect-engineer contracts. ...

48 CFR 636.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer contracts. 636.602 Section 636.602 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 636.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1536.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer contracts. 1536.602 Section 1536.602 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1536.602 Selection of firms for architect-engineer contracts. ...

48 CFR 2936.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer contracts. 2936.602 Section 2936.602 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 2936.602 Selection of firms for architect-engineer contracts. ...

48 CFR 436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer contracts. 436.602 Section 436.602 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Service 436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1336.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer contracts. 1336.602 Section 1336.602 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1336.602 Selection of firms for architect-engineer contracts. ...

48 CFR 636.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer contracts. 636.602 Section 636.602 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 636.602 Selection of firms for architect-engineer contracts. ...

48 CFR 536.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer contracts. 536.602 Section 536.602 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 536.602 Selection of firms for architect-engineer contracts. ...

48 CFR 36.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architect-engineer contracts. 36.602 Section 36.602 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 36.602 Selection of firms for architect-engineer contracts. ...

48 CFR 536.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architect-engineer contracts. 536.602 Section 536.602 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 536.602 Selection of firms for architect-engineer contracts. ...

48 CFR 636.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer contracts. 636.602 Section 636.602 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 636.602 Selection of firms for architect-engineer contracts. ...

48 CFR 36.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer contracts. 36.602 Section 36.602 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 36.602 Selection of firms for architect-engineer contracts. ...

48 CFR 2936.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer contracts. 2936.602 Section 2936.602 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 2936.602 Selection of firms for architect-engineer contracts. ...

48 CFR 36.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer contracts. 36.602 Section 36.602 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 36.602 Selection of firms for architect-engineer contracts. ...

48 CFR 36.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer contracts. 36.602 Section 36.602 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 36.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1536.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architect-engineer contracts. 1536.602 Section 1536.602 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1536.602 Selection of firms for architect-engineer contracts. ...

48 CFR 2936.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architect-engineer contracts. 2936.602 Section 2936.602 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 2936.602 Selection of firms for architect-engineer contracts. ...

48 CFR 536.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer contracts. 536.602 Section 536.602 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 536.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1336.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer contracts. 1336.602 Section 1336.602 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1336.602 Selection of firms for architect-engineer contracts. ...

48 CFR 436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer contracts. 436.602 Section 436.602 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Service 436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 536.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer contracts. 536.602 Section 536.602 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 536.602 Selection of firms for architect-engineer contracts. ...

48 CFR 2936.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer contracts. 2936.602 Section 2936.602 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 2936.602 Selection of firms for architect-engineer contracts. ...

48 CFR 36.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer contracts. 36.602 Section 36.602 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 36.602 Selection of firms for architect-engineer contracts. ...

48 CFR 436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer contracts. 436.602 Section 436.602 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Service 436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1336.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer contracts. 1336.602 Section 1336.602 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1336.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1536.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer contracts. 1536.602 Section 1536.602 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1536.602 Selection of firms for architect-engineer contracts. ...

48 CFR 2936.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer contracts. 2936.602 Section 2936.602 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 2936.602 Selection of firms for architect-engineer contracts. ...

48 CFR 636.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer contracts. 636.602 Section 636.602 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 636.602 Selection of firms for architect-engineer contracts. ...

48 CFR 436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer contracts. 436.602 Section 436.602 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Service 436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1536.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer contracts. 1536.602 Section 1536.602 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1536.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1336.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architect-engineer contracts. 1336.602 Section 1336.602 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1336.602 Selection of firms for architect-engineer contracts. ...

48 CFR 436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architect-engineer contracts. 436.602 Section 436.602 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Service 436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1336.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer contracts. 1336.602 Section 1336.602 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1336.602 Selection of firms for architect-engineer contracts. ...

48 CFR 536.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer contracts. 536.602 Section 536.602 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 536.602 Selection of firms for architect-engineer contracts. ...

48 CFR 636.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architect-engineer contracts. 636.602 Section 636.602 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 636.602 Selection of firms for architect-engineer contracts. ...

Tendon and ligament as novel cell sources for engineering the knee meniscus.

PubMed

Hadidi, P; Paschos, N K; Huang, B J; Aryaei, A; Hu, J C; Athanasiou, K A

2016-12-01

The application of cell-based therapies in regenerative medicine is hindered by the difficulty of acquiring adequate numbers of competent cells. For the knee meniscus in particular, this may be solved by harvesting tissue from neighboring tendons and ligaments. In this study, we have investigated the potential of cells from tendon and ligament, as compared to meniscus cells, to engineer scaffold-free self-assembling fibrocartilage. Self-assembling meniscus-shaped constructs engineered from a co-culture of articular chondrocytes and either meniscus, tendon, or ligament cells were cultured for 4 weeks with TGF-β1 in serum-free media. After culture, constructs were assessed for their mechanical properties, histological staining, gross appearance, and biochemical composition including cross-link content. Correlations were performed to evaluate relationships between biochemical content and mechanical properties. In terms of mechanical properties as well as biochemical content, constructs engineered using tenocytes and ligament fibrocytes were found to be equivalent or superior to constructs engineered using meniscus cells. Furthermore, cross-link content was found to be correlated with engineered tissue tensile properties. Tenocytes and ligament fibrocytes represent viable cell sources for engineering meniscus fibrocartilage using the self-assembling process. Due to greater cross-link content, fibrocartilage engineered with tenocytes and ligament fibrocytes may maintain greater tensile properties than fibrocartilage engineered with meniscus cells. Copyright © 2016 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

Tendon and ligament as novel cell sources for engineering the knee meniscus

PubMed Central

Hadidi, Pasha; Paschos, Nikolaos K.; Huang, Brian J.; Aryaei, Ashkan; Hu, Jerry C.; Athanasiou, Kyriacos A.

2016-01-01

Objective The application of cell-based therapies in regenerative medicine is hindered by the difficulty of acquiring adequate numbers of competent cells. For the knee meniscus in particular, this may be solved by harvesting tissue from neighboring tendons and ligaments. In this study, we have investigated the potential of cells from tendon and ligament, as compared to meniscus cells, to engineer scaffold-free self-assembling fibrocartilage. Method Self-assembling meniscus-shaped constructs engineered from a co-culture of articular chondrocytes and either meniscus, tendon, or ligament cells were cultured for 4 weeks with TGF-β1 in serum-free media. After culture, constructs were assessed for their mechanical properties, histological staining, gross appearance, and biochemical composition including cross-link content. Correlations were performed to evaluate relationships between biochemical content and mechanical properties. Results In terms of mechanical properties as well as biochemical content, constructs engineered using tenocytes and ligament fibrocytes were found to be equivalent or superior to constructs engineered using meniscus cells. Furthermore, cross-link content was found to be correlated with engineered tissue tensile properties. Conclusion Tenocytes and ligament fibrocytes represent viable cell sources for engineering meniscus fibrocartilage using the self-assembling process. Due to greater cross-link content, fibrocartilage engineered with tenocytes and ligament fibrocytes may maintain greater tensile properties than fibrocartilage engineered with meniscus cells. PMID:27473559

A Cost-Minimization Analysis of Tissue-Engineered Constructs for Corneal Endothelial Transplantation

PubMed Central

Tan, Tien-En; Peh, Gary S. L.; George, Benjamin L.; Cajucom-Uy, Howard Y.; Dong, Di; Finkelstein, Eric A.; Mehta, Jodhbir S.

2014-01-01

Corneal endothelial transplantation or endothelial keratoplasty has become the preferred choice of transplantation for patients with corneal blindness due to endothelial dysfunction. Currently, there is a worldwide shortage of transplantable tissue, and demand is expected to increase further with aging populations. Tissue-engineered alternatives are being developed, and are likely to be available soon. However, the cost of these constructs may impair their widespread use. A cost-minimization analysis comparing tissue-engineered constructs to donor tissue procured from eye banks for endothelial keratoplasty was performed. Both initial investment costs and recurring costs were considered in the analysis to arrive at a final tissue cost per transplant. The clinical outcomes of endothelial keratoplasty with tissue-engineered constructs and with donor tissue procured from eye banks were assumed to be equivalent. One-way and probabilistic sensitivity analyses were performed to simulate various possible scenarios, and to determine the robustness of the results. A tissue engineering strategy was cheaper in both investment cost and recurring cost. Tissue-engineered constructs for endothelial keratoplasty could be produced at a cost of US$880 per transplant. In contrast, utilizing donor tissue procured from eye banks for endothelial keratoplasty required US$3,710 per transplant. Sensitivity analyses performed further support the results of this cost-minimization analysis across a wide range of possible scenarios. The use of tissue-engineered constructs for endothelial keratoplasty could potentially increase the supply of transplantable tissue and bring the costs of corneal endothelial transplantation down, making this intervention accessible to a larger group of patients. Tissue-engineering strategies for corneal epithelial constructs or other tissue types, such as pancreatic islet cells, should also be subject to similar pharmacoeconomic analyses. PMID:24949869

A cost-minimization analysis of tissue-engineered constructs for corneal endothelial transplantation.

PubMed

Tan, Tien-En; Peh, Gary S L; George, Benjamin L; Cajucom-Uy, Howard Y; Dong, Di; Finkelstein, Eric A; Mehta, Jodhbir S

2014-01-01

Corneal endothelial transplantation or endothelial keratoplasty has become the preferred choice of transplantation for patients with corneal blindness due to endothelial dysfunction. Currently, there is a worldwide shortage of transplantable tissue, and demand is expected to increase further with aging populations. Tissue-engineered alternatives are being developed, and are likely to be available soon. However, the cost of these constructs may impair their widespread use. A cost-minimization analysis comparing tissue-engineered constructs to donor tissue procured from eye banks for endothelial keratoplasty was performed. Both initial investment costs and recurring costs were considered in the analysis to arrive at a final tissue cost per transplant. The clinical outcomes of endothelial keratoplasty with tissue-engineered constructs and with donor tissue procured from eye banks were assumed to be equivalent. One-way and probabilistic sensitivity analyses were performed to simulate various possible scenarios, and to determine the robustness of the results. A tissue engineering strategy was cheaper in both investment cost and recurring cost. Tissue-engineered constructs for endothelial keratoplasty could be produced at a cost of US$880 per transplant. In contrast, utilizing donor tissue procured from eye banks for endothelial keratoplasty required US$3,710 per transplant. Sensitivity analyses performed further support the results of this cost-minimization analysis across a wide range of possible scenarios. The use of tissue-engineered constructs for endothelial keratoplasty could potentially increase the supply of transplantable tissue and bring the costs of corneal endothelial transplantation down, making this intervention accessible to a larger group of patients. Tissue-engineering strategies for corneal epithelial constructs or other tissue types, such as pancreatic islet cells, should also be subject to similar pharmacoeconomic analyses.

Assessing and Controlling Blast Noise Emission: SARNAM Noise Impact Software

DTIC Science & Technology

2007-12-29

Engineers, Engineer Research and Development Center Jeffery Mifflin U.S. Army Corps of Engineers, Engineer Research and Development Center Kristy A...PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) U.S. Army Engineer Research and Development Center (ERDC) Construction Engineering Research Laboratory...6 Figure 5. OneShot control page

Dollar Summary of Federal Supply Classification and Service Category by Company, FY83, Part 5 (N065-W059).

DTIC Science & Technology

1983-01-01

BLDGS 1,269 PHILLIPS SWAGER ASSOCIATES ILLINOIS ARMY A/E CONSTRUCTION /ADMIN 9 SVC BLDGS 174 QUINLIVIAN PIERIK KRAUSE ROBSON JV NEW YORK NAVY A/E...CONSTRUCTION /AIRFIELD & MSL FAC RANCORN WILDMAN & KRAUSE VIRGINIA NAVY A/E CONSTRUCTION /AIRFIELD & MSL FAC REED ALONZO B MASS ARMY A/E CONSTRUCTION...ARCHITECT/ENGINEER - GENERAL CONTRACTOR TOTAL OUADRA ENGINEERING INC ALASKA OCE ARCHITECT/ENGINEER - GENERAL QUINLIVAN PIERIK & KRAUSE MASS ARMY ARCHITECT

Evaluating the Construct-Coverage of the e-rater[R] Scoring Engine. Research Report. ETS RR-09-01

ERIC Educational Resources Information Center

Quinlan, Thomas; Higgins, Derrick; Wolff, Susanne

2009-01-01

This report evaluates the construct coverage of the e-rater[R[ scoring engine. The matter of construct coverage depends on whether one defines writing skill, in terms of process or product. Originally, the e-rater engine consisted of a large set of components with a proven ability to predict human holistic scores. By organizing these capabilities…

Compendium of Administrators of Land Use and Related Programs. Revision

DTIC Science & Technology

1982-09-01

construction engineering research laboratory Army Nation Unitad Stoic«» Army ^ n * Technical Report N-40 (Revised) September 19 82...CONTRACT OR GRANT NUMBER’«) \\ 9. PERFORMING ORGANIZATION NAME AND ADDRESS U.S. ARMY CONSTRUCTION ENGINEERING RESEARCH LABORATORY...Chief of Engineers (OCE), under Project 4A762720A896, "Environmental Quality for Construction and Operation of Military Facilities" Task 04. "Land Use

Promoting Quality in NAVFAC (Naval Facilities Engineering Command) Construction.

DTIC Science & Technology

1986-01-01

experience. Inspector Checklists To assist their field construction engineers, Owens - Corning Fiberglas Corporation, in conjunction with Texas A&M...that developed by Owens - Corning Fiberglas A I Corporation to assist government inspectors to maintain high - quality standards in their construction...105, No. C03 (September 1979), 187-199. Information in a letter to the author from D.R. Eberts, Quality Assurance Engineer, Owens - Corning Fiberglas

48 CFR 1836.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer contracts. 1836.602 Section 1836.602 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1836.602 Selection of firms for architect-engineer contracts. ...

48 CFR 836.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architect-engineer contracts. 836.602 Section 836.602 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1836.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer contracts. 1836.602 Section 1836.602 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1836.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer contracts. 1436.602 Section 1436.602 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer contracts. 1436.602 Section 1436.602 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 836.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer contracts. 836.602 Section 836.602 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer contracts. 1436.602 Section 1436.602 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1836.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architect-engineer contracts. 1836.602 Section 1836.602 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1836.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1836.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer contracts. 1836.602 Section 1836.602 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1836.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer contracts. 1436.602 Section 1436.602 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1836.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer contracts. 1836.602 Section 1836.602 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1836.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architect-engineer contracts. 1436.602 Section 1436.602 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 836.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer contracts. 836.602 Section 836.602 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.602 Selection of firms for architect-engineer contracts. ...

48 CFR 836.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer contracts. 836.602 Section 836.602 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.602 Selection of firms for architect-engineer contracts. ...

48 CFR 836.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer contracts. 836.602 Section 836.602 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.602 Selection of firms for architect-engineer contracts. ...

This photographic copy of an engineering drawing shows floor plans, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

This photographic copy of an engineering drawing shows floor plans, sections and elevations of Building E-86, with details typical of the steel frame and "Transite" building construction at JPL Edwards Facility. California Institute of Technology, Jet Propulsion Laboratory, Facilities Engineering and Construction Office: "Casting & Curing, Building E-86, Floor Plan, Elevations & Section," drawing no. E86/6, 25 February 1977. California Institute of Technology, Jet Propulsion Laboratory, Plant Engineering: engineering drawings of structures at JPL Edwards Facility. Drawings on file at JPL Plant Engineering, Pasadena, California - Jet Propulsion Laboratory Edwards Facility, Casting & Curing Building, Edwards Air Force Base, Boron, Kern County, CA

Final Report on the Audit of Architect-Engineer Contracting at the Officer in Charge of Construction, Naval Facilities Engineering Command Contracts, Mediterranean, Madrid, Spain

DTIC Science & Technology

1990-11-30

This is our final report on the audit of Architect-Engineer Contracting for the Officer in Charge of Construction, Naval Facilities Engineering...Command Contracts, Mediterranean, for your information and use. This is the fourth in a series of reports issued as part of the audit of architect-engineer...A-E) contracting. The Contract Management Directorate made the audit from August 1989 through July 1990. When we expanded the audit scope to include

Micrometer scale guidance of mesenchymal stem cells to form structurally oriented large-scale tissue engineered cartilage.

PubMed

Chou, Chih-Ling; Rivera, Alexander L; Williams, Valencia; Welter, Jean F; Mansour, Joseph M; Drazba, Judith A; Sakai, Takao; Baskaran, Harihara

2017-09-15

Current clinical methods to treat articular cartilage lesions provide temporary relief of the symptoms but fail to permanently restore the damaged tissue. Tissue engineering, using mesenchymal stem cells (MSCs) combined with scaffolds and bioactive factors, is viewed as a promising method for repairing cartilage injuries. However, current tissue engineered constructs display inferior mechanical properties compared to native articular cartilage, which could be attributed to the lack of structural organization of the extracellular matrix (ECM) of these engineered constructs in comparison to the highly oriented structure of articular cartilage ECM. We previously showed that we can guide MSCs undergoing chondrogenesis to align using microscale guidance channels on the surface of a two-dimensional (2-D) collagen scaffold, which resulted in the deposition of aligned ECM within the channels and enhanced mechanical properties of the constructs. In this study, we developed a technique to roll 2-D collagen scaffolds containing MSCs within guidance channels in order to produce a large-scale, three-dimensional (3-D) tissue engineered cartilage constructs with enhanced mechanical properties compared to current constructs. After rolling the MSC-scaffold constructs into a 3-D cylindrical structure, the constructs were cultured for 21days under chondrogenic culture conditions. The microstructure architecture and mechanical properties of the constructs were evaluated using imaging and compressive testing. Histology and immunohistochemistry of the constructs showed extensive glycosaminoglycan (GAG) and collagen type II deposition. Second harmonic generation imaging and Picrosirius red staining indicated alignment of neo-collagen fibers within the guidance channels of the constructs. Mechanical testing indicated that constructs containing the guidance channels displayed enhanced compressive properties compared to control constructs without these channels. In conclusion, using a novel roll-up method, we have developed large scale MSC based tissue-engineered cartilage that shows microscale structural organization and enhanced compressive properties compared to current tissue engineered constructs. Tissue engineered cartilage constructs made with human mesenchymal stem cells (hMSCs), scaffolds and bioactive factors are a promising solution to treat cartilage defects. A major disadvantage of these constructs is their inferior mechanical properties compared to the native tissue, which is likely due to the lack of structural organization of the extracellular matrix of the engineered constructs. In this study, we developed three-dimensional (3-D) cartilage constructs from rectangular scaffold sheets containing hMSCs in micro-guidance channels and characterized their mechanical properties and metabolic requirements. The work led to a novel roll-up method to embed 2-D microscale structures in 3-D constructs. Further, micro-guidance channels incorporated within the 3-D cartilage constructs led to the production of aligned cell-produced matrix and enhanced mechanical function. Copyright © 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

Imaging Strategies for Tissue Engineering Applications

PubMed Central

Nam, Seung Yun; Ricles, Laura M.; Suggs, Laura J.

2015-01-01

Tissue engineering has evolved with multifaceted research being conducted using advanced technologies, and it is progressing toward clinical applications. As tissue engineering technology significantly advances, it proceeds toward increasing sophistication, including nanoscale strategies for material construction and synergetic methods for combining with cells, growth factors, or other macromolecules. Therefore, to assess advanced tissue-engineered constructs, tissue engineers need versatile imaging methods capable of monitoring not only morphological but also functional and molecular information. However, there is no single imaging modality that is suitable for all tissue-engineered constructs. Each imaging method has its own range of applications and provides information based on the specific properties of the imaging technique. Therefore, according to the requirements of the tissue engineering studies, the most appropriate tool should be selected among a variety of imaging modalities. The goal of this review article is to describe available biomedical imaging methods to assess tissue engineering applications and to provide tissue engineers with criteria and insights for determining the best imaging strategies. Commonly used biomedical imaging modalities, including X-ray and computed tomography, positron emission tomography and single photon emission computed tomography, magnetic resonance imaging, ultrasound imaging, optical imaging, and emerging techniques and multimodal imaging, will be discussed, focusing on the latest trends of their applications in recent tissue engineering studies. PMID:25012069

Towards organ printing: engineering an intra-organ branched vascular tree

PubMed Central

Visconti, Richard P; Kasyanov, Vladimir; Gentile, Carmine; Zhang, Jing; Markwald, Roger R; Mironov, Vladimir

2013-01-01

Importance of the field Effective vascularization of thick three-dimensional engineered tissue constructs is a problem in tissue engineering. As in native organs, a tissue-engineered intra-organ vascular tree must be comprised of a network of hierarchically branched vascular segments. Despite this requirement, current tissue-engineering efforts are still focused predominantly on engineering either large-diameter macrovessels or microvascular networks. Areas covered in this review We present the emerging concept of organ printing or robotic additive biofabrication of an intra-organ branched vascular tree, based on the ability of vascular tissue spheroids to undergo self-assembly. What the reader will gain The feasibility and challenges of this robotic biofabrication approach to intra-organ vascularization for tissue engineering based on organ-printing technology using self-assembling vascular tissue spheroids including clinically relevantly vascular cell sources are analyzed. Take home message It is not possible to engineer 3D thick tissue or organ constructs without effective vascularization. An effective intra-organ vascular system cannot be built by the simple connection of large-diameter vessels and microvessels. Successful engineering of functional human organs suitable for surgical implantation will require concomitant engineering of a ‘built in’ intra-organ branched vascular system. Organ printing enables biofabrication of human organ constructs with a ‘built in’ intra-organ branched vascular tree. PMID:20132061

On civil engineering disasters and their mitigation

NASA Astrophysics Data System (ADS)

Xie, Lili; Qu, Zhe

2018-01-01

Civil engineering works such as buildings and infrastructure are the carriers of human civilization. They are, however, also the origins of various types of disasters, which are referred to in this paper as civil engineering disasters. This paper presents the concept of civil engineering disasters, their characteristics, classification, causes, and mitigation technologies. Civil engineering disasters are caused primarily by civil engineering defects, which are usually attributed to improper selection of construction site, hazard assessment, design and construction, occupancy, and maintenance. From this viewpoint, many so-called natural disasters such as earthquakes, strong winds, floods, landslides, and debris flows are substantially due to civil engineering defects rather than the actual natural hazards. Civil engineering disasters occur frequently and globally and are the most closely related to human beings among all disasters. This paper emphasizes that such disasters can be mitigated mainly through civil engineering measures, and outlines the related objectives and scientific and technological challenges.

Review on antibacterial characteristics of bridge engineering biomaterials.

PubMed

Zhao, Qing-Qing; Chen, Meng-Yao; He, Rui-Lin; Zhang, Zhong-Feng; Ashraf, Muhammad Aqeel

2016-01-01

This review summarizes the research on timber construction materials used in bridge construction. It focuses on the application of antiseptic treatments and the use of timber engineering materials in decks and bridges. This review also provides an overview on the future research and prospects of engineered timber materials.

30 CFR 36.23 - Engine intake system.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Engine intake system. 36.23 Section 36.23... EQUIPMENT Construction and Design Requirements § 36.23 Engine intake system. (a) Construction. The intake... intake system without permanent deformation and shall prevent the propagation of flame through the joint...

Space Transportation System Western Launch Site Construction Management Information System - A Case Study.

DTIC Science & Technology

1979-09-01

The Corps of Engineers Management Information System (COEMIS) is used by the Corps of Engineers in their role as Construction Agents on Air Force...California. The research concluded that the Corps of Engineers Management Information System can be an effective, efficient management tool which has the

A modular approach to creating large engineered cartilage surfaces.

PubMed

Ford, Audrey C; Chui, Wan Fung; Zeng, Anne Y; Nandy, Aditya; Liebenberg, Ellen; Carraro, Carlo; Kazakia, Galateia; Alliston, Tamara; O'Connell, Grace D

2018-01-23

Native articular cartilage has limited capacity to repair itself from focal defects or osteoarthritis. Tissue engineering has provided a promising biological treatment strategy that is currently being evaluated in clinical trials. However, current approaches in translating these techniques to developing large engineered tissues remains a significant challenge. In this study, we present a method for developing large-scale engineered cartilage surfaces through modular fabrication. Modular Engineered Tissue Surfaces (METS) uses the well-known, but largely under-utilized self-adhesion properties of de novo tissue to create large scaffolds with nutrient channels. Compressive mechanical properties were evaluated throughout METS specimens, and the tensile mechanical strength of the bonds between attached constructs was evaluated over time. Raman spectroscopy, biochemical assays, and histology were performed to investigate matrix distribution. Results showed that by Day 14, stable connections had formed between the constructs in the METS samples. By Day 21, bonds were robust enough to form a rigid sheet and continued to increase in size and strength over time. Compressive mechanical properties and glycosaminoglycan (GAG) content of METS and individual constructs increased significantly over time. The METS technique builds on established tissue engineering accomplishments of developing constructs with GAG composition and compressive properties approaching native cartilage. This study demonstrated that modular fabrication is a viable technique for creating large-scale engineered cartilage, which can be broadly applied to many tissue engineering applications and construct geometries. Copyright © 2017 Elsevier Ltd. All rights reserved.

14 CFR 33.21 - Engine cooling.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Engine cooling. 33.21 Section 33.21 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; General § 33.21 Engine cooling. Engine design and...

48 CFR 436.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2012 CFR

2012-10-01

... for architect-engineer work. 436.605 Section 436.605 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Service 436.605 Government cost estimate for architect-engineer work. The contracting...

48 CFR 2436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architect-engineer contracts. 2436.602 Section 2436.602 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 2436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 2436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer contracts. 2436.602 Section 2436.602 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 2436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 436.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2013 CFR

2013-10-01

... for architect-engineer work. 436.605 Section 436.605 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Service 436.605 Government cost estimate for architect-engineer work. The contracting...

48 CFR 2436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer contracts. 2436.602 Section 2436.602 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 2436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 2436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer contracts. 2436.602 Section 2436.602 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 2436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 36.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2012 CFR

2012-10-01

... for architect-engineer work. 36.605 Section 36.605 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 36.605 Government cost estimate for architect-engineer work. (a) An independent...

48 CFR 1336.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2011 CFR

2011-10-01

... for architect-engineer work. 1336.605 Section 1336.605 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1336.605 Government cost estimate for architect-engineer work. After award, the...

48 CFR 1336.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2012 CFR

2012-10-01

... for architect-engineer work. 1336.605 Section 1336.605 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1336.605 Government cost estimate for architect-engineer work. After award, the...

48 CFR 2436.602 - Selection of firms for architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer contracts. 2436.602 Section 2436.602 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 2436.602 Selection of firms for architect-engineer contracts. ...

48 CFR 1336.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2013 CFR

2013-10-01

... for architect-engineer work. 1336.605 Section 1336.605 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1336.605 Government cost estimate for architect-engineer work. After award, the...

48 CFR 36.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2014 CFR

2014-10-01

... for architect-engineer work. 36.605 Section 36.605 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 36.605 Government cost estimate for architect-engineer work. (a) An independent...

48 CFR 36.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2010 CFR

2010-10-01

... for architect-engineer work. 36.605 Section 36.605 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 36.605 Government cost estimate for architect-engineer work. (a) An independent...

48 CFR 436.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2011 CFR

2011-10-01

... for architect-engineer work. 436.605 Section 436.605 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Service 436.605 Government cost estimate for architect-engineer work. The contracting...

48 CFR 436.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2010 CFR

2010-10-01

... for architect-engineer work. 436.605 Section 436.605 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Service 436.605 Government cost estimate for architect-engineer work. The contracting...

48 CFR 1336.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2010 CFR

2010-10-01

... for architect-engineer work. 1336.605 Section 1336.605 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1336.605 Government cost estimate for architect-engineer work. After award, the...

48 CFR 36.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2013 CFR

2013-10-01

... for architect-engineer work. 36.605 Section 36.605 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 36.605 Government cost estimate for architect-engineer work. (a) An independent...

48 CFR 436.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2014 CFR

2014-10-01

... for architect-engineer work. 436.605 Section 436.605 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Service 436.605 Government cost estimate for architect-engineer work. The contracting...

48 CFR 36.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2011 CFR

2011-10-01

... for architect-engineer work. 36.605 Section 36.605 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 36.605 Government cost estimate for architect-engineer work. (a) An independent...

48 CFR 1336.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2014 CFR

2014-10-01

... for architect-engineer work. 1336.605 Section 1336.605 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 1336.605 Government cost estimate for architect-engineer work. After award, the...

14 CFR 33.21 - Engine cooling.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Engine cooling. 33.21 Section 33.21 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; General § 33.21 Engine cooling. Engine design and...

14 CFR 33.21 - Engine cooling.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Engine cooling. 33.21 Section 33.21 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; General § 33.21 Engine cooling. Engine design and...

14 CFR 33.21 - Engine cooling.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Engine cooling. 33.21 Section 33.21 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; General § 33.21 Engine cooling. Engine design and...

14 CFR 33.21 - Engine cooling.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Engine cooling. 33.21 Section 33.21 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; General § 33.21 Engine cooling. Engine design and...

48 CFR 936.7101 - Construction contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Construction contracts... CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Inspection and Acceptance 936.7101 Construction contracts. (a) Inspection services may be performed by the architect-engineer responsible for the...

48 CFR 936.7101 - Construction contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Construction contracts... CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Inspection and Acceptance 936.7101 Construction contracts. (a) Inspection services may be performed by the architect-engineer responsible for the...

48 CFR 936.7101 - Construction contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Construction contracts... CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Inspection and Acceptance 936.7101 Construction contracts. (a) Inspection services may be performed by the architect-engineer responsible for the...

48 CFR 936.7101 - Construction contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Construction contracts... CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Inspection and Acceptance 936.7101 Construction contracts. (a) Inspection services may be performed by the architect-engineer responsible for the...

48 CFR 936.7101 - Construction contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Construction contracts... CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Inspection and Acceptance 936.7101 Construction contracts. (a) Inspection services may be performed by the architect-engineer responsible for the...

KSC-2012-6405

NASA Image and Video Library

2012-09-20

CAPE CANAVERAL, Fla. -- At NASA’s Kennedy Space Center in Florida, a groundbreaking was held to mark the start of construction on the Antenna Test Bed Array for the Ka-Band Objects Observation and Monitoring, or Ka-BOOM system. Using ceremonial shovels to mark the site, from left are Michael Le, lead design engineer and construction manager Sue Vingris, Cape Design Engineer Co. project manager Kannan Rengarajan, chief executive officer of Cape Design Engineer Co. Lutfi Mized, president of Cape Design Engineer Co. David Roelandt, construction site superintendent with Cape Design Engineer Co. Marc Seibert, NASA project manager Michael Miller, NASA project manager Peter Aragona, KSC’s Electromagnetic Lab manager Stacy Hopper, KSCs master planning supervisor Dr. Bary Geldzabler, NASA chief scientist and KSC’s Chief Technologist Karen Thompson. The construction site is near the former Vertical Processing Facility, which has been demolished. Workers will begin construction on the pile foundations for the 40-foot-diameter dish antenna arrays and their associated utilities, and prepare the site for the operations command center facility. Photo credit: NASA/Charisse Nahser

KSC-2012-6404

NASA Image and Video Library

2012-09-20

CAPE CANAVERAL, Fla. -- At NASA’s Kennedy Space Center in Florida, a groundbreaking was held to mark the start of construction on the Antenna Test Bed Array for the Ka-Band Objects Observation and Monitoring, or Ka-BOOM system. Holding ceremonial shovels, from left are Michael Le, lead design engineer and construction manager Sue Vingris, Cape Design Engineer Co. project manager Kannan Rengarajan, chief executive officer of Cape Design Engineer Co. Lutfi Mized, president of Cape Design Engineer Co. David Roelandt, construction site superintendent with Cape Design Engineer Co. Marc Seibert, NASA project manager Michael Miller, NASA project manager Peter Aragona, KSC’s Electromagnetic Lab manager Stacy Hopper, KSCs master planning supervisor Dr. Bary Geldzabler, NASA chief scientist and KSC’s Chief Technologist Karen Thompson. The construction site is near the former Vertical Processing Facility, which has been demolished. Workers will begin construction on the pile foundations for the 40-foot-diameter dish antenna arrays and their associated utilities, and prepare the site for the operations command center facility. Photo credit: NASA/Charisse Nahser

RESEARCH AND DESIGN ABOUT VERSATILE 3D-CAD ENGINE FOR CONSTRUCTION

NASA Astrophysics Data System (ADS)

Tanaka, Shigenori; Kubota, Satoshi; Kitagawa, Etsuji; Monobe, Kantaro; Nakamura, Kenji

In the construction field of Japan, it is an important subject to build the environment where 3D-CAD data is used for CALS/EC, information construction, and an improvement in productivity. However, in the construction field, 3D-CAD software does not exist under the present circumstances. Then, in order to support development of domestic 3D-CAD software, it is required to develop a 3D-CAD engine. In this research, in order to familiarize the 3D-CAD software at low cost and quickly and build the environment where the 3D-CAD software is utilizable, investigation for designing a 3D-CAD engine is proposed. The target for investigation are the use scene of 3D-CAD, the seeds which accompany 3D-CAD, a standardization trend, existing products, IT component engineering. Based on results of the investigation, the functional requirements for the 3D-CAD engine for the construction field were concluded.

Relative Economy of Different Methods of Airplane Construction

NASA Technical Reports Server (NTRS)

Herrmann, H

1931-01-01

A comparison of the relative economy of airplane construction shows that monoplanes are cheaper than biplanes; that all-metal construction is much more expensive than mixed construction; that multi-engine airplanes are more expensive than single-engine types of the same carrying capacity and speed;that the cost of airplanes is materially reduced by increasing their size without increasing the number of engines. The greatest economy usually coincides with the best aerodynamic and static conditions and the cost is always increased by safety requirements.

Methodology discourses as boundary work in the construction of engineering education.

PubMed

Beddoes, Kacey

2014-04-01

Engineering education research is a new field that emerged in the social sciences over the past 10 years. This analysis of engineering education research demonstrates that methodology discourses have played a central role in the construction and development of the field of engineering education, and that they have done so primarily through boundary work. This article thus contributes to science and technology studies literature by examining the role of methodology discourses in an emerging social science field. I begin with an overview of engineering education research before situating the case within relevant bodies of literature on methodology discourses and boundary work. I then identify two methodology discourses--rigor and methodological diversity--and discuss how they contribute to the construction and development of engineering education research. The article concludes with a discussion of how the findings relate to prior research on methodology discourses and boundary work and implications for future research.

Possibility of reducing CO2 emissions from internal combustion engines

NASA Astrophysics Data System (ADS)

Drabik, Dawid; Mamala, Jarosław; Śmieja, Michał; Prażnowski, Krzysztof

2017-10-01

Article defines on the possibility of reduction CO2 of the internal combustion engine and presents the analysis based on originally conducted studies. The increase in overall engine efficiency is sought after by all engineers dealing with engine construction, one of the major ways to reduce CO2 emissions is to increase the compression ratio. The application of the compression ratio that has been increased constructional in the engine will, on one hand, bring about the increase in the theoretical efficiency, but, on the other hand, require a system for pressure control at a higher engine load in order to prevent engine knocking. For the purposes of the article there was carried out a number of studies and compiled results, and on their basis determined what have a major impact on the reducing CO2.

Design type air engine Di Pietro

NASA Astrophysics Data System (ADS)

Zwierzchowski, Jaroslaw

The article presents a pneumatic engine constructed by Angelo Di Pietro. 3D solid models of pneumatic engine components were presented therein. A directional valve is a key element of the control system. The valve functions as a camshaft distributing air to particular engine chambers. The construction designed by Angelo Di Pietro is modern and innovative. A pneumatic engine requires low pressure to start rotary movement. With the use of CFD software, the fields of velocity vectors' distribution were determined. Moreover, the author determined the distribution of pressure values in engine inlet and outlet channels. CFD model studies on engine operation were conducted for chosen stages of operating cycles. On the basis of simulation tests that were conducted, the values of flow rates for the engine were determined. The distribution of pressure values made it possible to evaluate the torque value on the rotating shaft.

Engineering cartilage or endochondral bone: a comparison of different naturally derived hydrogels.

PubMed

Sheehy, Eamon J; Mesallati, Tariq; Vinardell, Tatiana; Kelly, Daniel J

2015-02-01

Cartilaginous tissues engineered using mesenchymal stem cells (MSCs) have been shown to generate bone in vivo by executing an endochondral programme. This may hinder the use of MSCs for articular cartilage regeneration, but opens the possibility of using engineered cartilaginous tissues for large bone defect repair. Hydrogels may be an attractive tool in the scaling-up of such tissue engineered grafts for endochondral bone regeneration. In this study, we compared the capacity of different naturally derived hydrogels (alginate, chitosan and fibrin) to support chondrogenesis and hypertrophy of MSCs in vitro and endochondral ossification in vivo. In vitro, alginate and chitosan constructs accumulated the highest levels of sulfated glycosaminoglycan (sGAG), with chitosan constructs synthesizing the highest levels of collagen. Alginate and fibrin constructs supported the greatest degree of calcium accumulation, though only fibrin constructs calcified homogeneously. In vivo, chitosan constructs facilitated neither vascularization nor endochondral ossification, and also retained the greatest amount of sGAG, suggesting it to be a more suitable material for the engineering of articular cartilage. Both alginate and fibrin constructs facilitated vascularization and endochondral bone formation as well as the development of a bone marrow environment. Alginate constructs accumulated significantly more mineral and supported greater bone formation in central regions of the engineered tissue. In conclusion, this study demonstrates the capacity of chitosan hydrogels to promote and better maintain a chondrogenic phenotype in MSCs and highlights the potential of utilizing alginate hydrogels for MSC-based endochondral bone tissue engineering applications. Copyright © 2014 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

7 CFR 1753.17 - Engineering services.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 11 2014-01-01 2014-01-01 false Engineering services. 1753.17 Section 1753.17... AGRICULTURE TELECOMMUNICATIONS SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Engineering Services § 1753.17 Engineering services. (a)(1) All engineering services required by a borrower to support its application for a...

7 CFR 1753.17 - Engineering services.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 11 2010-01-01 2010-01-01 false Engineering services. 1753.17 Section 1753.17... AGRICULTURE TELECOMMUNICATIONS SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Engineering Services § 1753.17 Engineering services. (a)(1) All engineering services required by a borrower to support its application for a...

7 CFR 1753.17 - Engineering services.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 11 2011-01-01 2011-01-01 false Engineering services. 1753.17 Section 1753.17... AGRICULTURE TELECOMMUNICATIONS SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Engineering Services § 1753.17 Engineering services. (a)(1) All engineering services required by a borrower to support its application for a...

7 CFR 1753.17 - Engineering services.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 11 2013-01-01 2013-01-01 false Engineering services. 1753.17 Section 1753.17... AGRICULTURE TELECOMMUNICATIONS SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Engineering Services § 1753.17 Engineering services. (a)(1) All engineering services required by a borrower to support its application for a...

7 CFR 1753.17 - Engineering services.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 11 2012-01-01 2012-01-01 false Engineering services. 1753.17 Section 1753.17... AGRICULTURE TELECOMMUNICATIONS SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Engineering Services § 1753.17 Engineering services. (a)(1) All engineering services required by a borrower to support its application for a...

48 CFR 36.609-3 - Work oversight in architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer contracts. 36.609-3 Section 36.609-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 36.609-3 Work oversight in architect-engineer contracts. The contracting officer...

48 CFR 836.606-71 - Architect-engineer's proposal.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Architect-engineer's... AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.606-71 Architect-engineer's proposal. (a) When the contract price is estimated to be $50,000...

48 CFR 836.606-71 - Architect-engineer's proposal.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Architect-engineer's... AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.606-71 Architect-engineer's proposal. (a) When the contract price is estimated to be $50,000...

48 CFR 836.606-71 - Architect-engineer's proposal.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Architect-engineer's... AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.606-71 Architect-engineer's proposal. (a) When the contract price is estimated to be $50,000...

48 CFR 36.609-3 - Work oversight in architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer contracts. 36.609-3 Section 36.609-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 36.609-3 Work oversight in architect-engineer contracts. The contracting officer...

48 CFR 36.609-3 - Work oversight in architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architect-engineer contracts. 36.609-3 Section 36.609-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 36.609-3 Work oversight in architect-engineer contracts. The contracting officer...

48 CFR 36.609-3 - Work oversight in architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer contracts. 36.609-3 Section 36.609-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 36.609-3 Work oversight in architect-engineer contracts. The contracting officer...

48 CFR 836.606-71 - Architect-engineer's proposal.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Architect-engineer's... AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.606-71 Architect-engineer's proposal. (a) When the contract price is estimated to be $50,000...

48 CFR 836.606-71 - Architect-engineer's proposal.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Architect-engineer's... AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.606-71 Architect-engineer's proposal. (a) When the contract price is estimated to be $50,000...

48 CFR 36.609-3 - Work oversight in architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer contracts. 36.609-3 Section 36.609-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 36.609-3 Work oversight in architect-engineer contracts. The contracting officer...

Mechanics of oriented electrospun nanofibrous scaffolds for annulus fibrosus tissue engineering.

PubMed

Nerurkar, Nandan L; Elliott, Dawn M; Mauck, Robert L

2007-08-01

Engineering a functional replacement for the annulus fibrosus (AF) of the intervertebral disc is contingent upon recapitulation of AF structure, composition, and mechanical properties. In this study, we propose a new paradigm for AF tissue engineering that focuses on the reconstitution of anatomic fiber architecture and uses constitutive modeling to evaluate construct function. A modified electrospinning technique was utilized to generate aligned nanofibrous polymer scaffolds for engineering the basic functional unit of the AF, a single lamella. Scaffolds were tested in uniaxial tension at multiple fiber orientations, demonstrating a nonlinear dependence of modulus on fiber angle that mimicked the nonlinearity and anisotropy of native AF. A homogenization model previously applied to native AF successfully described scaffold mechanical response, and parametric studies demonstrated that nonfibrillar matrix, along with fiber connectivity, are key contributors to tensile mechanics for engineered AF. We demonstrated that AF cells orient themselves along the aligned scaffolds and deposit matrix that contributes to construct mechanics under loading conditions relevant to the in vivo environment. The homogenization model was applied to cell-seeded constructs and provided quantitative measures for the evolution of matrix and interfibrillar interactions. Finally, the model demonstrated that at fiber angles of the AF (28 degrees -44 degrees ), engineered material behaved much like native tissue, suggesting that engineered constructs replicate the physiologic behavior of the single AF lamella. Constitutive modeling provides a powerful tool for analysis of engineered AF neo-tissue and native AF tissue alike, highlighting key mechanical design criteria for functional AF tissue engineering.

48 CFR 227.7107 - Contracts for architect-engineer services.

Code of Federal Regulations, 2014 CFR

2014-10-01

...-engineer services. 227.7107 Section 227.7107 Federal Acquisition Regulations System DEFENSE ACQUISITION... Rights in Technical Data 227.7107 Contracts for architect-engineer services. This section sets forth... of construction and architect-engineer services. ...

48 CFR 227.7107 - Contracts for architect-engineer services.

Code of Federal Regulations, 2011 CFR

2011-10-01

...-engineer services. 227.7107 Section 227.7107 Federal Acquisition Regulations System DEFENSE ACQUISITION... Rights in Technical Data 227.7107 Contracts for architect-engineer services. This section sets forth... of construction and architect-engineer services. ...

48 CFR 227.7107 - Contracts for architect-engineer services.

Code of Federal Regulations, 2013 CFR

2013-10-01

...-engineer services. 227.7107 Section 227.7107 Federal Acquisition Regulations System DEFENSE ACQUISITION... Rights in Technical Data 227.7107 Contracts for architect-engineer services. This section sets forth... of construction and architect-engineer services. ...

48 CFR 227.7107 - Contracts for architect-engineer services.

Code of Federal Regulations, 2010 CFR

2010-10-01

...-engineer services. 227.7107 Section 227.7107 Federal Acquisition Regulations System DEFENSE ACQUISITION... Rights in Technical Data 227.7107 Contracts for architect-engineer services. This section sets forth... of construction and architect-engineer services. ...

48 CFR 227.7107 - Contracts for architect-engineer services.

Code of Federal Regulations, 2012 CFR

2012-10-01

...-engineer services. 227.7107 Section 227.7107 Federal Acquisition Regulations System DEFENSE ACQUISITION... Rights in Technical Data 227.7107 Contracts for architect-engineer services. This section sets forth... of construction and architect-engineer services. ...

14 CFR 33.11 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-01-01

... STANDARDS: AIRCRAFT ENGINES Design and Construction; General § 33.11 Applicability. This subpart prescribes the general design and construction requirements for reciprocating and turbine aircraft engines. ...

14 CFR 33.11 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-01-01

... STANDARDS: AIRCRAFT ENGINES Design and Construction; General § 33.11 Applicability. This subpart prescribes the general design and construction requirements for reciprocating and turbine aircraft engines. ...

48 CFR 836.606-73 - Application of 6 percent architect-engineer fee limitation.

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer fee limitation. 836.606-73 Section 836.606-73 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.606-73 Application of 6 percent architect-engineer fee limitation...

48 CFR 836.606-73 - Application of 6 percent architect-engineer fee limitation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer fee limitation. 836.606-73 Section 836.606-73 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.606-73 Application of 6 percent architect-engineer fee limitation...

48 CFR 836.606-73 - Application of 6 percent architect-engineer fee limitation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer fee limitation. 836.606-73 Section 836.606-73 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.606-73 Application of 6 percent architect-engineer fee limitation...

48 CFR 836.606-73 - Application of 6 percent architect-engineer fee limitation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer fee limitation. 836.606-73 Section 836.606-73 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.606-73 Application of 6 percent architect-engineer fee limitation...

14 CFR 33.70 - Engine life-limited parts.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Engine life-limited parts. 33.70 Section 33.70 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.70 Engine life...

14 CFR 33.70 - Engine life-limited parts.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Engine life-limited parts. 33.70 Section 33.70 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.70 Engine life...

48 CFR 736.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2013 CFR

2013-10-01

... for architect-engineer work. 736.605 Section 736.605 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 736.605 Government cost estimate for architect-engineer work. See 736.602-3(c)(5). ...

48 CFR 736.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2010 CFR

2010-10-01

... for architect-engineer work. 736.605 Section 736.605 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 736.605 Government cost estimate for architect-engineer work. See 736.602-3(c)(5). ...

48 CFR 736.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2014 CFR

2014-10-01

... for architect-engineer work. 736.605 Section 736.605 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 736.605 Government cost estimate for architect-engineer work. See 736.602-3(c)(5). ...

48 CFR 736.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2012 CFR

2012-10-01

... for architect-engineer work. 736.605 Section 736.605 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 736.605 Government cost estimate for architect-engineer work. See 736.602-3(c)(5). ...

48 CFR 736.605 - Government cost estimate for architect-engineer work.

Code of Federal Regulations, 2011 CFR

2011-10-01

... for architect-engineer work. 736.605 Section 736.605 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 736.605 Government cost estimate for architect-engineer work. See 736.602-3(c)(5). ...

Detonation Jet Engine. Part 2--Construction Features

ERIC Educational Resources Information Center

Bulat, Pavel V.; Volkov, Konstantin N.

2016-01-01

We present the most relevant works on jet engine design that utilize thermodynamic cycle of detonative combustion. Detonation engines of various concepts, pulse detonation, rotational and engine with stationary detonation wave, are reviewed. Main trends in detonation engine development are discussed. The most important works that carried out…

14 CFR 33.35 - Fuel and induction system.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Fuel and induction system. 33.35 Section 33... AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Reciprocating Aircraft Engines § 33.35 Fuel and induction system. (a) The fuel system of the engine must be designed and constructed to supply an...

14 CFR 33.35 - Fuel and induction system.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Fuel and induction system. 33.35 Section 33... AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Reciprocating Aircraft Engines § 33.35 Fuel and induction system. (a) The fuel system of the engine must be designed and constructed to supply an...

14 CFR 33.35 - Fuel and induction system.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Fuel and induction system. 33.35 Section 33... AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Reciprocating Aircraft Engines § 33.35 Fuel and induction system. (a) The fuel system of the engine must be designed and constructed to supply an...

14 CFR 33.35 - Fuel and induction system.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Fuel and induction system. 33.35 Section 33... AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Reciprocating Aircraft Engines § 33.35 Fuel and induction system. (a) The fuel system of the engine must be designed and constructed to supply an...

14 CFR 33.39 - Lubrication system.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Lubrication system. 33.39 Section 33.39... system. (a) The lubrication system of the engine must be designed and constructed so that it will... supply is in the engine. (b) The lubrication system of the engine must be designed and constructed to...

Design Guide for Selection and Specification of Kevlar Rope for Ocean Engineering and Construction.

DTIC Science & Technology

1976-07-01

public rtoieco cnd sol . It i Idim .buttm Is ul"rnimi.. OCEAN ENGINEERING AND CONSTRUCTION PROJECT OFFICE CHESAPEAKE DIVISION NAVAL FACILITIES ENGINEERING...be to have no more than one layer. This is impractical for oceano - graphic purposes. Assuming a need to spooi many layers of rope under tension

Development of a construction engineering manpower system for Georgia DOT.

DOT National Transportation Integrated Search

1994-07-01

The objective of this special research study was to develop a construction engineering manpower management system based primarily on construction dollars and to determine if this type of system will be adequate for the GDOT.

14 CFR 33.63 - Vibration.

Code of Federal Regulations, 2011 CFR

2011-01-01

... and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.63 Vibration. Each engine... range of rotational speeds and power/thrust, without inducing excessive stress in any engine part...

14 CFR 33.63 - Vibration.

Code of Federal Regulations, 2010 CFR

2010-01-01

... and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.63 Vibration. Each engine... range of rotational speeds and power/thrust, without inducing excessive stress in any engine part...

Science and Engineering

ERIC Educational Resources Information Center

Cowin, Roy; Reyes-Guerra, David

1977-01-01

Engineers may be involved in various functions such as research, development, planning, design (analysis and synthesis), construction, operation and management of engineering projects. This article discusses some branches of accredited engineering curricula, employment opportunities, the preparation for management, minimum education needed, women…

Cells for tissue engineering of cardiac valves.

PubMed

Jana, Soumen; Tranquillo, Robert T; Lerman, Amir

2016-10-01

Heart valve tissue engineering is a promising alternative to prostheses for the replacement of diseased or damaged heart valves, because tissue-engineered valves have the ability to remodel, regenerate and grow. To engineer heart valves, cells are harvested, seeded onto or into a three-dimensional (3D) matrix platform to generate a tissue-engineered construct in vitro, and then implanted into a patient's body. Successful engineering of heart valves requires a thorough understanding of the different types of cells that can be used to obtain the essential phenotypes that are expressed in native heart valves. This article reviews different cell types that have been used in heart valve engineering, cell sources for harvesting, phenotypic expression in constructs and suitability in heart valve tissue engineering. Natural and synthetic biomaterials that have been applied as scaffold systems or cell-delivery platforms are discussed with each cell type. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

48 CFR 936.609-3 - Work oversight in architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer contracts. 936.609-3 Section 936.609-3 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 936.609-3 Work oversight in architect-engineer contracts. In addition to the clause at 48...

48 CFR 936.609-3 - Work oversight in architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer contracts. 936.609-3 Section 936.609-3 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 936.609-3 Work oversight in architect-engineer contracts. In addition to the clause at 48...

48 CFR 936.609-3 - Work oversight in architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer contracts. 936.609-3 Section 936.609-3 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 936.609-3 Work oversight in architect-engineer contracts. In addition to the clause at 48...

48 CFR 936.609-3 - Work oversight in architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer contracts. 936.609-3 Section 936.609-3 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 936.609-3 Work oversight in architect-engineer contracts. In addition to the clause at 48...

48 CFR 936.609-3 - Work oversight in architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... architect-engineer contracts. 936.609-3 Section 936.609-3 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 936.609-3 Work oversight in architect-engineer contracts. In addition to the clause at 48...

Metabolic engineering of Escherichia coli for the production of phenylpyruvate derivatives.

PubMed

Liu, Shuang Ping; Zhang, Liang; Mao, Jian; Ding, Zhong Yang; Shi, Gui Yang

2015-11-01

Phenylpyruvate derivatives (PPD), such as phenylpropanoids, DL-phenylglycine, dl-phenylalanine, and styrene, are biosynthesized using phenylpyruvate as the precursor. They are widely used in human health and nutrition products. Recently, metabolic engineering provides effective strategies to develop PPD producers. Based on phenylpyruvate-producing chassis, genetically defined PPD producers have been successfully constructed. In this work, the most recent information on genetics and on the molecular mechanisms regulating phenylpyruvate synthesis pathways in Escherichia coli are summarized, and the engineering strategies to construct the PPD producers are also discussed. The enzymes and pathways are proposed for PPD-producer constructions, and potential difficulties in strain construction are also identified and discussed. With respect to recent advances in synthetic biology, future strategies to construct efficiently producers are discussed. Copyright © 2015 International Metabolic Engineering Society. Published by Elsevier Inc. All rights reserved.

48 CFR 836.602-4 - Selection authority.

Code of Federal Regulations, 2011 CFR

2011-10-01

... CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.602-4 Selection authority. The Director, Office of Construction and Facilities Management (for Central Office contracts), the Director, Office of Construction Management (for National Cemetery Administration contracts...

48 CFR 836.602-4 - Selection authority.

Code of Federal Regulations, 2012 CFR

2012-10-01

... CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.602-4 Selection authority. The Director, Office of Construction and Facilities Management (for Central Office contracts), the Director, Office of Construction Management (for National Cemetery Administration contracts...

48 CFR 836.602-4 - Selection authority.

Code of Federal Regulations, 2014 CFR

2014-10-01

... CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.602-4 Selection authority. The Director, Office of Construction and Facilities Management (for Central Office contracts), the Director, Office of Construction Management (for National Cemetery Administration contracts...

48 CFR 836.602-4 - Selection authority.

Code of Federal Regulations, 2013 CFR

2013-10-01

... CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.602-4 Selection authority. The Director, Office of Construction and Facilities Management (for Central Office contracts), the Director, Office of Construction Management (for National Cemetery Administration contracts...

Predicting on-site environmental impacts of municipal engineering works

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gangolells, Marta, E-mail: marta.gangolells@upc.edu; Casals, Miquel, E-mail: miquel.casals@upc.edu; Forcada, Núria, E-mail: nuria.forcada@upc.edu

2014-01-15

The research findings fill a gap in the body of knowledge by presenting an effective way to evaluate the significance of on-site environmental impacts of municipal engineering works prior to the construction stage. First, 42 on-site environmental impacts of municipal engineering works were identified by means of a process-oriented approach. Then, 46 indicators and their corresponding significance limits were determined on the basis of a statistical analysis of 25 new-build and remodelling municipal engineering projects. In order to ensure the objectivity of the assessment process, direct and indirect indicators were always based on quantitative data from the municipal engineering projectmore » documents. Finally, two case studies were analysed and found to illustrate the practical use of the proposed model. The model highlights the significant environmental impacts of a particular municipal engineering project prior to the construction stage. Consequently, preventive actions can be planned and implemented during on-site activities. The results of the model also allow a comparison of proposed municipal engineering projects and alternatives with respect to the overall on-site environmental impact and the absolute importance of a particular environmental aspect. These findings are useful within the framework of the environmental impact assessment process, as they help to improve the identification and evaluation of on-site environmental aspects of municipal engineering works. The findings may also be of use to construction companies that are willing to implement an environmental management system or simply wish to improve on-site environmental performance in municipal engineering projects. -- Highlights: • We present a model to predict the environmental impacts of municipal engineering works. • It highlights significant on-site environmental impacts prior to the construction stage. • Findings are useful within the environmental impact assessment process. • They also help contractors to implement environmental management systems.« less

48 CFR 48.102 - Policies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... VALUE ENGINEERING Policies and Procedures 48.102 Policies. (a) As required by Section 36 of the Office... cost-effective value engineering procedures and processes. Agencies shall provide contractors a... engineering provisions in appropriate supply, service, architect-engineer and construction contracts as...

AUTOMOTIVE DIESEL MAINTENANCE 1. UNIT XXIX, REVIEWING THE CONSTRUCTION OF ENGINE COMPONENTS.

ERIC Educational Resources Information Center

Human Engineering Inst., Cleveland, OH.

THIS MODULE OF A 30-MODULE COURSE IS DESIGNED TO PROVIDE A REVIEW OF THE CONSTRUCTION AND OPERATION OF DIESEL ENGINE COMPONENTS. TOPICS ARE STATIONARY PARTS, ENGINE MOVING PARTS, PISTON RINGS, AND CONNECTING RODS AND PISTON PINS. THE MODULE CONSISTS OF AN INSTRUCTOR'S GUIDE, TRANSPARENCIES, A LIST OF SUGGESTED SUPPLEMENTARY MATERIALS, AND TRAINEE…

Advancing Integrated STEM Learning through Engineering Design: Sixth-Grade Students' Design and Construction of Earthquake Resistant Buildings

ERIC Educational Resources Information Center

English, Lyn D.; King, Donna; Smeed, Joanna

2017-01-01

As part of a 3-year longitudinal study, 136 sixth-grade students completed an engineering-based problem on earthquakes involving integrated STEM learning. Students employed engineering design processes and STEM disciplinary knowledge to plan, sketch, then construct a building designed to withstand earthquake damage, taking into account a number of…

Final Environmental Assessment: Addressing Construction of a New Civil Engineering Workshop at Bellows Air Force Station, O’ahu, Hawaii

DTIC Science & Technology

2010-03-01

FINAL ENVIRONMENTAL ASSESSMENT ADDRESSING CONSTRUCTION OF A NEW CIVIL ENGINEERING WORKSHOP AT BELLOWS AIR FORCE STATION , O‘AHU, HAWAI‘I...Minimize impacts on other Bellows AFS functions and environmental resources This alternative would be located in an area located near Building 546 and...Preparation of An Environmental Assessment for the Proposed Construction of New Civil Engineering Workshop at Bellows Air !Force Station Thank you

Multimedia techniques for construction education and training : final report.

DOT National Transportation Integrated Search

2017-02-01

The current profession of civil engineering often focuses education and training on code compliance rather than constructability and construction techniques. Also, it is well accepted that it takes a decade or more for engineers to develop a high-lev...

Engineering Play: Exploring Associations with Executive Function, Mathematical Ability, and Spatial Ability in Preschool

ERIC Educational Resources Information Center

Gold, Zachary Samuel

2017-01-01

Engineering play is a new perspective on preschool education that views constructive play as an engineering design process that parallels the way engineers think and work when they develop engineered solutions to human problems (Bairaktarova, Evangelou, Bagiati, & Brophy, 2011). Early research from this perspective supports its use in framing…

Knowledge, attitude and practices for design for safety: A study on civil & structural engineers.

PubMed

Goh, Yang Miang; Chua, Sijie

2016-08-01

Design for safety (DfS) (also known as prevention through design, safe design and Construction (Design and Management)) promotes early consideration of safety and health hazards during the design phase of a construction project. With early intervention, hazards can be more effectively eliminated or controlled leading to safer worksites and construction processes. DfS is practiced in many countries, including Australia, the UK, and Singapore. In Singapore, the Manpower Ministry enacted the DfS Regulations in July 2015, which will be enforced from August 2016 onwards. Due to the critical role of civil and structural (C&S) engineers during design and construction, the DfS knowledge, attitude and practices (KAP) of C&S engineers have significant impact on the successful implementation of DfS. Thus, this study aims to explore the DfS KAP of C&S engineers so as to guide further research in measuring and improving DfS KAP of designers. During the study, it was found that there is a lack of KAP studies in construction management. Therefore, this study also aims to provide useful lessons for future applications of the KAP framework in construction management research. A questionnaire was developed to assess the DfS KAP of C&S engineers. The responses provided by 43 C&S engineers were analyzed. In addition, interviews with experienced construction professionals were carried out to further understand perceptions of DfS and related issues. The results suggest that C&S engineers are supportive of DfS, but the level of DfS knowledge and practices need to be improved. More DfS guidelines and training should be made available to the engineers. To ensure that DfS can be implemented successfully, there is a need to study the contractual arrangements between clients and designers and the effectiveness of different implementation approaches for the DfS process. The questionnaire and findings in this study provided the foundation for a baseline survey with larger sample size, which is currently being planned. In contrast to earlier studies, the study showed that the responding C&S engineers were supportive of the DfS. The study showed that the key to improving the DfS KAP of C&S engineers is by improving clients' motivation for DfS. Copyright © 2015 Elsevier Ltd. All rights reserved.

3D Printed Vascular Networks Enhance Viability in High-Volume Perfusion Bioreactor.

PubMed

Ball, Owen; Nguyen, Bao-Ngoc B; Placone, Jesse K; Fisher, John P

2016-12-01

There is a significant clinical need for engineered bone graft substitutes that can quickly, effectively, and safely repair large segmental bone defects. One emerging field of interest involves the growth of engineered bone tissue in vitro within bioreactors, the most promising of which are perfusion bioreactors. Using bioreactor systems, tissue engineered bone constructs can be fabricated in vitro. However, these engineered constructs lack inherent vasculature and once implanted, quickly develop a necrotic core, where no nutrient exchange occurs. Here, we utilized COMSOL modeling to predict oxygen diffusion gradients throughout aggregated alginate constructs, which allowed for the computer-aided design of printable vascular networks, compatible with any large tissue engineered construct cultured in a perfusion bioreactor. We investigated the effect of 3D printed macroscale vascular networks with various porosities on the viability of human mesenchymal stem cells in vitro, using both gas-permeable, and non-gas permeable bioreactor growth chamber walls. Through the use of 3D printed vascular structures in conjunction with a tubular perfusion system bioreactor, cell viability was found to increase by as much as 50% in the core of these constructs, with in silico modeling predicting construct viability at steady state.

3D Printed Vascular Networks Enhance Viability in High-Volume Perfusion Bioreactor

PubMed Central

Ball, Owen; Nguyen, Bao-Ngoc B.; Placone, Jesse K.; Fisher, John P.

2016-01-01

There is a significant clinical need for engineered bone graft substitutes that can quickly, effectively, and safely repair large segmental bone defects. One emerging field of interest involves the growth of engineered bone tissue in vitro within bioreactors, the most promising of which are perfusion bioreactors. Using bioreactor systems, tissue engineered bone constructs can be fabricated in vitro. However, these engineered constructs lack inherent vasculature and once implanted, quickly develop a necrotic core, where no nutrient exchange occurs. Here, we utilized COMSOL modeling to predict oxygen diffusion gradients throughout aggregated alginate constructs, which allowed for the computer-aided design of printable vascular networks, compatible with any large tissue engineered construct cultured in a perfusion bioreactor. We investigated the effect of 3D printed macroscale vascular networks with various porosities on the viability of human mesenchymal stem cells in vitro, using both gas-permeable, and non-gas permeable bioreactor growth chamber walls. Through the use of 3D printed vascular structures in conjunction with a tubular perfusion system bioreactor, cell viability was found to increase by as much as 50% in the core of these constructs, with in silico modeling predicting construct viability at steady state. PMID:27272210

An Analog Computer for Electronic Engineering Education

ERIC Educational Resources Information Center

Fitch, A. L.; Iu, H. H. C.; Lu, D. D. C.

2011-01-01

This paper describes a compact analog computer and proposes its use in electronic engineering teaching laboratories to develop student understanding of applications in analog electronics, electronic components, engineering mathematics, control engineering, safe laboratory and workshop practices, circuit construction, testing, and maintenance. The…

23 CFR 627.3 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-04-01

... HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS VALUE ENGINEERING... construction. Value Engineering (VE) analysis. The systematic process of reviewing and assessing a project by a...; and (3) Reducing the time to develop and deliver the project. Value Engineering (VE) Job Plan. A...

23 CFR 627.3 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS VALUE ENGINEERING... construction. Value Engineering (VE) analysis. The systematic process of reviewing and assessing a project by a...; and (3) Reducing the time to develop and deliver the project. Value Engineering (VE) Job Plan. A...

Marine Engine-Exhaust Emissions Test Cell

DOT National Transportation Integrated Search

1974-11-01

A marine engine exhaust emissions test cell for boat-size diesel engines (approx. 200 hp) and outboard engines was constructed as part of a project sponsored by the United States Coast Guard for the monitoring and control of emissions from marine sou...

The Nutating Engine-Prototype Engine Progress Report and Test Results

NASA Technical Reports Server (NTRS)

Meitner, Peter L.; Boruta, Mike

2006-01-01

A prototype of a new, internal combustion (IC) engine concept has been completed. The Nutating Engine features an internal disk nutating (wobbling) on a Z-shaped power shaft. The engine is exceedingly compact, and several times more power dense than any conventional (reciprocating or rotary) IC engine. This paper discusses lessons learned during the prototype engine's development and provides details of its construction. In addition, results of the initial performance tests of the various components, as well as the complete engine, are summarized.

The experimental study of genetic engineering human neural stem cells mediated by lentivirus to express multigene.

PubMed

Cai, Pei-qiang; Tang, Xun; Lin, Yue-qiu; Martin, Oudega; Sun, Guang-yun; Xu, Lin; Yang, Yun-kang; Zhou, Tian-hua

2006-02-01

To explore the feasibility to construct genetic engineering human neural stem cells (hNSCs) mediated by lentivirus to express multigene in order to provide a graft source for further studies of spinal cord injury (SCI). Human neural stem cells from the brain cortex of human abortus were isolated and cultured, then gene was modified by lentivirus to express both green fluorescence protein (GFP) and rat neurotrophin-3 (NT-3); the transgenic expression was detected by the methods of fluorescence microscope, dorsal root ganglion of fetal rats and slot blot. Genetic engineering hNSCs were successfully constructed. All of the genetic engineering hNSCs which expressed bright green fluorescence were observed under the fluorescence microscope. The conditioned medium of transgenic hNSCs could induce neurite flourishing outgrowth from dorsal root ganglion (DRG). The genetic engineering hNSCs expressed high level NT-3 which could be detected by using slot blot. Genetic engineering hNSCs mediated by lentivirus can be constructed to express multigene successfully.

[Development of computer aided forming techniques in manufacturing scaffolds for bone tissue engineering].

PubMed

Wei, Xuelei; Dong, Fuhui

2011-12-01

To review recent advance in the research and application of computer aided forming techniques for constructing bone tissue engineering scaffolds. The literature concerning computer aided forming techniques for constructing bone tissue engineering scaffolds in recent years was reviewed extensively and summarized. Several studies over last decade have focused on computer aided forming techniques for bone scaffold construction using various scaffold materials, which is based on computer aided design (CAD) and bone scaffold rapid prototyping (RP). CAD include medical CAD, STL, and reverse design. Reverse design can fully simulate normal bone tissue and could be very useful for the CAD. RP techniques include fused deposition modeling, three dimensional printing, selected laser sintering, three dimensional bioplotting, and low-temperature deposition manufacturing. These techniques provide a new way to construct bone tissue engineering scaffolds with complex internal structures. With rapid development of molding and forming techniques, computer aided forming techniques are expected to provide ideal bone tissue engineering scaffolds.

3D bioprinting for vascularized tissue fabrication

PubMed Central

Richards, Dylan; Jia, Jia; Yost, Michael; Markwald, Roger; Mei, Ying

2016-01-01

3D bioprinting holds remarkable promise for rapid fabrication of 3D tissue engineering constructs. Given its scalability, reproducibility, and precise multi-dimensional control that traditional fabrication methods do not provide, 3D bioprinting provides a powerful means to address one of the major challenges in tissue engineering: vascularization. Moderate success of current tissue engineering strategies have been attributed to the current inability to fabricate thick tissue engineering constructs that contain endogenous, engineered vasculature or nutrient channels that can integrate with the host tissue. Successful fabrication of a vascularized tissue construct requires synergy between high throughput, high-resolution bioprinting of larger perfusable channels and instructive bioink that promotes angiogenic sprouting and neovascularization. This review aims to cover the recent progress in the field of 3D bioprinting of vascularized tissues. It will cover the methods of bioprinting vascularized constructs, bioink for vascularization, and perspectives on recent innovations in 3D printing and biomaterials for the next generation of 3D bioprinting for vascularized tissue fabrication. PMID:27230253

Closed-loop recycling of construction and demolition waste in Germany in view of stricter environmental threshold values.

PubMed

Weil, Marcel; Jeske, Udo; Schebek, Liselotte

2006-06-01

Recycling of construction and demolition waste contributes decisively to the saving of natural mineral resources. In Germany, processed mineral construction and demolition waste from structural engineering is used nearly exclusively in civil engineering (earthwork and road construction sector) as open-loop recycling. Due to the planned stricter limit values for the protection of soil and water, however, this recycling path in civil engineering may no longer be applicable in the future. According to some new guidelines and standards adopted recently, recycled aggregates may also be used for concrete production in the structural engineering sector (closed-loop recycling). Wastes from the structural engineering sector can thus be kept in a closed cycle, and their disposal on a landfill can be avoided. The present report focuses on the determination of maximum waste volumes that may be handled by this new recycling option. Potential adverse effects on the saving of resources and climate protection have been analysed. For this purpose, materials flow analysis and ecobalancing methods have been used.

Solar power satellite system definition study. Part 2, volume 5: Space operations (construction and transportation)

NASA Technical Reports Server (NTRS)

Miller, K.; Davis, E. E.

1977-01-01

Construction and transportation systems and operations are described for the following combinations: (1) silicon photovoltaic CR=1 satellite constructed primarily in low earth orbit (LEO); (2) silicon photovoltaic CR=1 satellite constructed in geosynchronous earth orbit (GEO); (3) Rankine thermal engine satellite constructed primarily in LEO; and (4) Rankine thermal engine satellite constructed in GEO.

Cartilage constructs engineered from chondrocytes overexpressing IGF-I improve the repair of osteochondral defects in a rabbit model.

PubMed

Madry, H; Kaul, G; Zurakowski, D; Vunjak-Novakovic, G; Cucchiarini, M

2013-04-16

Tissue engineering combined with gene therapy is a promising approach for promoting articular cartilage repair. Here, we tested the hypothesis that engineered cartilage with chondrocytes overexpressing a human insulin-like growth factor I (IGF-I) gene can enhance the repair of osteochondral defects, in a manner dependent on the duration of cultivation. Genetically modified chondrocytes were cultured on biodegradable polyglycolic acid scaffolds in dynamic flow rotating bioreactors for either 10 or 28 d. The resulting cartilaginous constructs were implanted into osteochondral defects in rabbit knee joints. After 28 weeks of in vivo implantation, immunoreactivity to ß-gal was detectable in the repair tissue of defects that received lacZ constructs. Engineered cartilaginous constructs based on IGF-I-overexpressing chondrocytes markedly improved osteochondral repair compared with control (lacZ) constructs. Moreover, IGF-I constructs cultivated for 28 d in vitro significantly promoted osteochondral repair vis-à-vis similar constructs cultivated for 10 d, leading to significantly decreased osteoarthritic changes in the cartilage adjacent to the defects. Hence, the combination of spatially defined overexpression of human IGF-I within a tissue-engineered construct and prolonged bioreactor cultivation resulted in most enhanced articular cartilage repair and reduction of osteoarthritic changes in the cartilage adjacent to the defect. Such genetically enhanced tissue engineering provides a versatile tool to evaluate potential therapeutic genes in vivo and to improve our comprehension of the development of the repair tissue within articular cartilage defects. Insights gained with additional exploration using this model may lead to more effective treatment options for acute cartilage defects.

CARTILAGE CONSTRUCTS ENGINEERED FROM CHONDROCYTES OVEREXPRESSING IGF-I IMPROVE THE REPAIR OF OSTEOCHONDRAL DEFECTS IN A RABBIT MODEL

PubMed Central

Madry, Henning; Kaul, Gunter; Zurakowski, David; Vunjak-Novakovic, Gordana; Cucchiarini, Magali

2015-01-01

Tissue engineering combined with gene therapy is a promising approach for promoting articular cartilage repair. Here, we tested the hypothesis that engineered cartilage with chondrocytes over expressing a human insulin-like growth factor I (IGF-I) gene can enhance the repair of osteochondral defects, in a manner dependent on the duration of cultivation. Genetically modified chondrocytes were cultured on biodegradable polyglycolic acid scaffolds in dynamic flow rotating bioreactors for either 10 or 28 d. The resulting cartilaginous constructs were implanted into osteochondral defects in rabbit knee joints. After 28 weeks of in vivo implantation, immunoreactivity to ß-gal was detectable in the repair tissue of defects that received lacZ constructs. Engineered cartilaginous constructs based on IGF-I-over expressing chondrocytes markedly improved osteochondral repair compared with control (lacZ) constructs. Moreover, IGF-I constructs cultivated for 28 d in vitro significantly promoted osteochondral repair vis-à-vis similar constructs cultivated for 10 d, leading to significantly decreased osteoarthritic changes in the cartilage adjacent to the defects. Hence, the combination of spatially defined overexpression of human IGF-I within a tissue-engineered construct and prolonged bioreactor cultivation resulted in most enhanced articular cartilage repair and reduction of osteoarthritic changes in the cartilage adjacent to the defect. Such genetically enhanced tissue engineering provides a versatile tool to evaluate potential therapeutic genes in vivo and to improve our comprehension of the development of the repair tissue within articular cartilage defects. Insights gained with additional exploration using this model may lead to more effective treatment options for acute cartilage defects. PMID:23588785

Microvascular Guidance: A Challenge to Support the Development of Vascularised Tissue Engineering Construct

PubMed Central

Sukmana, Irza

2012-01-01

The guidance of endothelial cell organization into a capillary network has been a long-standing challenge in tissue engineering. Some research efforts have been made to develop methods to promote capillary networks inside engineered tissue constructs. Capillary and vascular networks that would mimic blood microvessel function can be used to subsequently facilitate oxygen and nutrient transfer as well as waste removal. Vascularization of engineering tissue construct is one of the most favorable strategies to overpass nutrient and oxygen supply limitation, which is often the major hurdle in developing thick and complex tissue and artificial organ. This paper addresses recent advances and future challenges in developing three-dimensional culture systems to promote tissue construct vascularization allowing mimicking blood microvessel development and function encountered in vivo. Bioreactors systems that have been used to create fully vascularized functional tissue constructs will also be outlined. PMID:22623881

48 CFR 936.202-70 - Specifications charges.

Code of Federal Regulations, 2011 CFR

2011-10-01

... payments, the invitations for bids should so state, and the architect-engineer or construction management... CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 936.202-70 Specifications charges. (a) To support all invitations for bids, plans and...

48 CFR 936.202-70 - Specifications charges.

Code of Federal Regulations, 2012 CFR

2012-10-01

... payments, the invitations for bids should so state, and the architect-engineer or construction management... CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 936.202-70 Specifications charges. (a) To support all invitations for bids, plans and...

48 CFR 936.202-70 - Specifications charges.

Code of Federal Regulations, 2013 CFR

2013-10-01

... payments, the invitations for bids should so state, and the architect-engineer or construction management... CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 936.202-70 Specifications charges. (a) To support all invitations for bids, plans and...

48 CFR 936.202-70 - Specifications charges.

Code of Federal Regulations, 2014 CFR

2014-10-01

... payments, the invitations for bids should so state, and the architect-engineer or construction management... CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 936.202-70 Specifications charges. (a) To support all invitations for bids, plans and...

7 CFR 1726.404 - Non-site specific construction contract closeout.

Code of Federal Regulations, 2014 CFR

2014-01-01

... UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE ELECTRIC SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Contract... equipment is supplied under a construction contract, the borrower (acting through its engineer, if... equipment. The borrower (acting through its engineer, if applicable) will schedule such inspection and...

7 CFR 1726.404 - Non-site specific construction contract closeout.

Code of Federal Regulations, 2010 CFR

2010-01-01

... UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE ELECTRIC SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Contract... equipment is supplied under a construction contract, the borrower (acting through its engineer, if... equipment. The borrower (acting through its engineer, if applicable) will schedule such inspection and...

7 CFR 1726.404 - Non-site specific construction contract closeout.

Code of Federal Regulations, 2011 CFR

2011-01-01

... UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE ELECTRIC SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Contract... equipment is supplied under a construction contract, the borrower (acting through its engineer, if... equipment. The borrower (acting through its engineer, if applicable) will schedule such inspection and...

7 CFR 1726.404 - Non-site specific construction contract closeout.

Code of Federal Regulations, 2012 CFR

2012-01-01

... UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE ELECTRIC SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Contract... equipment is supplied under a construction contract, the borrower (acting through its engineer, if... equipment. The borrower (acting through its engineer, if applicable) will schedule such inspection and...

7 CFR 1726.404 - Non-site specific construction contract closeout.

Code of Federal Regulations, 2013 CFR

2013-01-01

... UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE ELECTRIC SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Contract... equipment is supplied under a construction contract, the borrower (acting through its engineer, if... equipment. The borrower (acting through its engineer, if applicable) will schedule such inspection and...

48 CFR 936.202-70 - Specifications charges.

Code of Federal Regulations, 2010 CFR

2010-10-01

... payments, the invitations for bids should so state, and the architect-engineer or construction management... CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 936.202-70 Specifications charges. (a) To support all invitations for bids, plans and...

Constructively Aligned Teaching and Learning in Higher Education in Engineering: What Do Students Perceive as Contributing to the Learning of Interdisciplinary Thinking?

ERIC Educational Resources Information Center

Spelt, E. J. H.; Luning, P. A.; van Boekel, M. A. J. S.; Mulder, M.

2015-01-01

Increased attention to the need for constructively aligned teaching and learning in interdisciplinary higher education in engineering is observed. By contrast, little research has been conducted on the implementation of the outcome-based pedagogical approach to interdisciplinary higher education in engineering. Therefore, the present design-based…

1+1=3: Cross-Discipline Collaboration Really Adds Up!

ERIC Educational Resources Information Center

Breen, Mindy

2006-01-01

The Department of Engineering & Design at Eastern Washington University (EWU) offers a bachelor of arts degree in visual communication design and bachelor of science degrees in mechanical engineering technology, manufacturing technology, construction technology, design technology, electrical engineering, computer engineering technology and…

14 CFR 33.70 - Engine life-limited parts.

Code of Federal Regulations, 2014 CFR

2014-01-01

... parts are rotor and major static structural parts whose primary failure is likely to result in a....70 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.70 Engine life...

14 CFR 33.66 - Bleed air system.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.66 Bleed air system. The engine must supply bleed air without adverse effect on the engine, excluding reduced thrust or power...

14 CFR 33.74 - Continued rotation.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.74 Continued rotation. If any of the engine main rotating systems continue to rotate after the engine is shutdown for any reason...

14 CFR 33.67 - Fuel system.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.67 Fuel system. (a) With fuel supplied to the engine at the flow and pressure specified by the applicant, the engine must...

14 CFR 33.66 - Bleed air system.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.66 Bleed air system. The engine must supply bleed air without adverse effect on the engine, excluding reduced thrust or power...

14 CFR 33.74 - Continued rotation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.74 Continued rotation. If any of the engine main rotating systems continue to rotate after the engine is shutdown for any reason...

14 CFR 33.67 - Fuel system.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.67 Fuel system. (a) With fuel supplied to the engine at the flow and pressure specified by the applicant, the engine must...

14 CFR 33.69 - Ignitions system.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.69 Ignitions system. Each engine must be equipped with an ignition system for starting the engine on the ground and in flight. An...

14 CFR 33.69 - Ignitions system.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.69 Ignitions system. Each engine must be equipped with an ignition system for starting the engine on the ground and in flight. An...

7 CFR 1780.55 - Preliminary engineering reports and Environmental Reports.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 12 2011-01-01 2011-01-01 false Preliminary engineering reports and Environmental..., Designing, Bidding, Contracting, Constructing and Inspections § 1780.55 Preliminary engineering reports and Environmental Reports. Preliminary engineering reports (PERs) must conform to customary professional standards...

7 CFR 1780.55 - Preliminary engineering reports and Environmental Reports.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 12 2012-01-01 2012-01-01 false Preliminary engineering reports and Environmental..., Designing, Bidding, Contracting, Constructing and Inspections § 1780.55 Preliminary engineering reports and Environmental Reports. Preliminary engineering reports (PERs) must conform to customary professional standards...

7 CFR 1780.55 - Preliminary engineering reports and Environmental Reports.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 12 2014-01-01 2013-01-01 true Preliminary engineering reports and Environmental..., Designing, Bidding, Contracting, Constructing and Inspections § 1780.55 Preliminary engineering reports and Environmental Reports. Preliminary engineering reports (PERs) must conform to customary professional standards...

7 CFR 1780.55 - Preliminary engineering reports and Environmental Reports.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 12 2010-01-01 2010-01-01 false Preliminary engineering reports and Environmental..., Designing, Bidding, Contracting, Constructing and Inspections § 1780.55 Preliminary engineering reports and Environmental Reports. Preliminary engineering reports (PERs) must conform to customary professional standards...

7 CFR 1780.55 - Preliminary engineering reports and Environmental Reports.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 12 2013-01-01 2013-01-01 false Preliminary engineering reports and Environmental..., Designing, Bidding, Contracting, Constructing and Inspections § 1780.55 Preliminary engineering reports and Environmental Reports. Preliminary engineering reports (PERs) must conform to customary professional standards...

32 CFR 555.2 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Experiment Station (WES), the U.S. Army Construction Engineering Research Laboratory (CERL), the U.S. Army Engineer Topographic Laboratories (ETL), the U.S. Army Coastal Engineering Research Center (CERC), the U.S... CEMETERIES CORPS OF ENGINEERS, RESEARCH AND DEVELOPMENT, LABORATORY RESEARCH AND DEVELOPMENT AND TESTS, WORK...

14 CFR 33.17 - Fire protection.

Code of Federal Regulations, 2011 CFR

2011-01-01

... STANDARDS: AIRCRAFT ENGINES Design and Construction; General § 33.17 Fire protection. (a) The design and... addition, the design and construction of turbine engines must minimize the probability of the occurrence of...

25 CFR 900.122 - What does an Indian tribe or tribal organization do if it wants to secure a construction contract?

Code of Federal Regulations, 2010 CFR

2010-04-01

... UNDER THE INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Construction § 900.122 What does an... information available about the construction project, including construction drawings, maps, engineering... tribal organization to review all plans, specifications, engineering reports, cost estimates, and other...

Small Engine Repair Course Outline.

ERIC Educational Resources Information Center

DeClouet, Fred

Small engines as referred to here are engines used on lawn mowers, chain saws, power plants, outboards, and cycles. It does not include engines used on automobiles. The course outlined is intended to show how small two-cycle and four-cycle gas engines are constructed, how they operate, what goes wrong, and how to service and repair them. It is…

48 CFR 52.248-3 - Value Engineering-Construction.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Value Engineering....248-3 Value Engineering—Construction. As prescribed in 48.202, insert the following clause: Value Engineering—Construction (OCT 2010) (a) General. The Contractor is encouraged to develop, prepare, and submit...

48 CFR 52.248-3 - Value Engineering-Construction.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Value Engineering....248-3 Value Engineering—Construction. As prescribed in 48.202, insert the following clause: Value Engineering—Construction (OCT 2010) (a) General. The Contractor is encouraged to develop, prepare, and submit...

48 CFR 52.248-3 - Value Engineering-Construction.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Value Engineering....248-3 Value Engineering—Construction. As prescribed in 48.202, insert the following clause: Value Engineering—Construction (OCT 2010) (a) General. The Contractor is encouraged to develop, prepare, and submit...

48 CFR 52.248-3 - Value Engineering-Construction.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Value Engineering....248-3 Value Engineering—Construction. As prescribed in 48.202, insert the following clause: Value Engineering—Construction (OCT 2010) (a) General. The Contractor is encouraged to develop, prepare, and submit...

48 CFR 52.248-3 - Value Engineering-Construction.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Value Engineering....248-3 Value Engineering—Construction. As prescribed in 48.202, insert the following clause: Value Engineering—Construction (OCT 2010) (a) General. The Contractor is encouraged to develop, prepare, and submit...

Monitoring sinew contraction during formation of tissue-engineered fibrin-based ligament constructs.

PubMed

Paxton, Jennifer Z; Wudebwe, Uchena N G; Wang, Anqi; Woods, Daniel; Grover, Liam M

2012-08-01

The ability to study the gross morphological changes occurring during tissue formation is vital to producing tissue-engineered structures of clinically relevant dimensions in vitro. Here, we have used nondestructive methods of digital imaging and optical coherence tomography to monitor the early-stage formation and subsequent maturation of fibrin-based tissue-engineered ligament constructs. In addition, the effect of supplementation with essential promoters of collagen synthesis, ascorbic acid (AA) and proline (P), has been assessed. Contraction of the cell-seeded fibrin gel occurs unevenly within the first 5 days of culture around two fixed anchor points before forming a longitudinal ligament-like construct. AA+P supplementation accelerates gel contraction in the maturation phase of development, producing ligament-like constructs with a higher collagen content and distinct morphology to that of unsupplemented constructs. These studies highlight the importance of being able to control the methods of tissue formation and maturation in vitro to enable the production of tissue-engineered constructs with suitable replacement tissue characteristics for repair of clinical soft-tissue injuries.

Principles of Naval Engineering.

ERIC Educational Resources Information Center

Naval Personnel Program Support Activity, Washington, DC.

Fundamentals of shipboard machinery, equipment, and engineering plants are presented in this text prepared for engineering officers. A general description is included of the development of naval ships, ship design and construction, stability and buoyancy, and damage and casualty control. Engineering theories are explained on the background of ship…

48 CFR 236.102 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Office of the Chief of Engineers, Naval Facilities Engineering Command, or Air Force Directorate of Civil Engineering. Marshallese firm is defined in the provision at 252.236-7012, Military Construction on Kwajalein... that— (1) Is responsible for the architectural, engineering, and other related technical aspects of the...

48 CFR 236.102 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Office of the Chief of Engineers, Naval Facilities Engineering Command, or Air Force Directorate of Civil Engineering. Marshallese firm is defined in the provision at 252.236-7012, Military Construction on Kwajalein... that— (1) Is responsible for the architectural, engineering, and other related technical aspects of the...

48 CFR 236.102 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Office of the Chief of Engineers, Naval Facilities Engineering Command, or Air Force Directorate of Civil Engineering. Marshallese firm is defined in the provision at 252.236-7012, Military Construction on Kwajalein... that— (1) Is responsible for the architectural, engineering, and other related technical aspects of the...

48 CFR 236.102 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Office of the Chief of Engineers, Naval Facilities Engineering Command, or Air Force Directorate of Civil Engineering. Marshallese firm is defined in the provision at 252.236-7012, Military Construction on Kwajalein... that— (1) Is responsible for the architectural, engineering, and other related technical aspects of the...

14 CFR 33.64 - Pressurized engine static parts.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Pressurized engine static parts. 33.64 Section 33.64 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.64 Pressurized...

14 CFR 33.64 - Pressurized engine static parts.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Pressurized engine static parts. 33.64 Section 33.64 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.64 Pressurized...

14 CFR 33.64 - Pressurized engine static parts.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Pressurized engine static parts. 33.64 Section 33.64 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.64 Pressurized...

14 CFR 33.64 - Pressurized engine static parts.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Pressurized engine static parts. 33.64 Section 33.64 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.64 Pressurized...

14 CFR 33.64 - Pressurized engine static parts.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Pressurized engine static parts. 33.64 Section 33.64 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.64 Pressurized...

32 CFR 555.2 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... FOR OTHERS § 555.2 Applicability. This regulation applies to the U.S. Army Engineer Waterways Experiment Station (WES), the U.S. Army Construction Engineering Research Laboratory (CERL), the U.S. Army Engineer Topographic Laboratories (ETL), the U.S. Army Coastal Engineering Research Center (CERC), the U.S...

32 CFR 555.2 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-07-01

... FOR OTHERS § 555.2 Applicability. This regulation applies to the U.S. Army Engineer Waterways Experiment Station (WES), the U.S. Army Construction Engineering Research Laboratory (CERL), the U.S. Army Engineer Topographic Laboratories (ETL), the U.S. Army Coastal Engineering Research Center (CERC), the U.S...

32 CFR 555.2 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-07-01

... FOR OTHERS § 555.2 Applicability. This regulation applies to the U.S. Army Engineer Waterways Experiment Station (WES), the U.S. Army Construction Engineering Research Laboratory (CERL), the U.S. Army Engineer Topographic Laboratories (ETL), the U.S. Army Coastal Engineering Research Center (CERC), the U.S...

32 CFR 555.2 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-07-01

... FOR OTHERS § 555.2 Applicability. This regulation applies to the U.S. Army Engineer Waterways Experiment Station (WES), the U.S. Army Construction Engineering Research Laboratory (CERL), the U.S. Army Engineer Topographic Laboratories (ETL), the U.S. Army Coastal Engineering Research Center (CERC), the U.S...

Development of an integrated indicator system to assess the impacts of reclamation engineering on a river estuary.

PubMed

Xu, Yan; Cai, Yanpeng; Sun, Tao; Yin, Xin'An; Tan, Qian

2017-06-30

An integrated indicator system was developed for determining synthetic environmental responses under multiple types of coastal reclamation engineering in the Yellow River estuary, China. Four types of coastal engineering works were analyzed, namely port construction, petroleum exploitation, fishery and aquaculture, and seawall defense. In addition, two areas with limited human disturbances were considered for comparison. From the weights of the response value for each indicator, port construction was determined to be the primary impact contributor among the four engineering works studies. Specifically, hydrodynamic conditions, ecological status, economic costs, and engineering intensity were on average 72.78%, 65.03%, 75.03%, and 66.35% higher than those of other engineering types. Furthermore, fishery and aquaculture impact on water quality was 42.51% higher than that of other engineering types, whereas seawall defense impact on landscape variation was 51.75% higher than that of other engineering types. The proposed indicator system may provide effective coastal management in future. Copyright © 2017 Elsevier Ltd. All rights reserved.

Engineering Microvascularized 3D Tissue Using Alginate-Chitosan Microcapsules.

PubMed

Zhang, Wujie; Choi, Jung K; He, Xiaoming

2017-02-01

Construction of vascularized tissues is one of the major challenges of tissue engineering. The goal of this study was to engineer 3D microvascular tissues by incorporating the HUVEC-CS cells with a collagen/alginate-chitosan (AC) microcapsule scaffold. In the presence of AC microcapsules, a 3D vascular-like network was clearly observable. The results indicated the importance of AC microcapsules in engineering microvascular tissues -- providing support and guiding alignment of HUVEC-CS cells. This approach provides an alternative and promising method for constructing vascularized tissues.

Details of the Construction and Production of Fuel Pumps and Fuel Nozzles for the Airplane Diesel Engine

NASA Technical Reports Server (NTRS)

Lubenetsky, W S

1936-01-01

This report presents investigations into the design and construction of fuel pumps for diesel engines. The results of the pump tests on the engines showed that, with a good cut-off, accurate injection, assured by the proper adjustment of the pump elements, there is a decrease in the consumption of fuel and hence an increase in the rated power of the engine. Some of the aspects investigated include: cam profile, coefficient of discharge, and characteristics of the injection system.

Fabrication of a Neotrachea Using Engineered Cartilage

PubMed Central

Weidenbecher, Mark; Tucker, Harvey M.; Awadallah, Amad; Dennis, James E.

2008-01-01

Objectives Surgical management of long-segment tracheal stenosis is an ongoing problem. Many types of tracheal prostheses have been tried but with limited success because of immune rejection, graft ischemia, or restenosis. Tissue engineered cartilage may offer a solution to this problem, although scaffolds, which are currently often used for support, can lead to biocompatibility problems. This study investigated the feasibility of scaffold-free cartilage to tissue engineer a vascularized neotrachea in rabbits. Study Design Animal study. Methods Autologous neotracheal constructs were implanted in the abdomen of six New Zealand white rabbits. Auricular chondrocytes were used to engineer scaffold-free cartilage sheets. A muscle flap raised from the external abdominal oblique muscle and the engineered cartilage were wrapped around a silicone stent to fabricate a vascularized neotrachea in vivo. In two of the six rabbits, a full thickness skin graft was used to create an epithelial lining. The constructs were harvested after either 6 or 10 weeks. Results All neotracheal constructs were healthy with well-vascularized and integrated layers. The implanted engineered cartilage underwent a remodeling process, forming a solid tracheal framework. Constructs harvested after 10 weeks proved to have significantly better mechanical properties than after 6 weeks and were comparable with the rabbit's native trachea. Conclusion Scaffold-free engineered cartilage can successfully fabricate a well-vascularized, autologous neotrachea with excellent mechanical properties. The results suggest that this approach can be used to reconstruct tracheal defects in rabbits. PMID:18197138

Flood trends and river engineering on the Mississippi River system

USGS Publications Warehouse

Pinter, N.; Jemberie, A.A.; Remo, J.W.F.; Heine, R.A.; Ickes, B.S.

2008-01-01

Along >4000 km of the Mississippi River system, we document that climate, land-use change, and river engineering have contributed to statistically significant increases in flooding over the past 100-150 years. Trends were tested using a database of >8 million hydrological measurements. A geospatial database of historical engineering construction was used to quantify the response of flood levels to each unit of engineering infrastructure. Significant climate- and/or land use-driven increases in flow were detected, but the largest and most pervasive contributors to increased flooding on the Mississippi River system were wing dikes and related navigational structures, followed by progressive levee construction. In the area of the 2008 Upper Mississippi flood, for example, about 2 m of the flood crest is linked to navigational and flood-control engineering. Systemwide, large increases in flood levels were documented at locations and at times of wing-dike and levee construction. Copyright 2008 by the American Geophysical Union.

The Crosstalk between Tissue Engineering and Pharmaceutical Biotechnology: Recent Advances and Future Directions.

PubMed

Pacheco, Daniela P; Reis, Rui L; Correlo, Vítor M; Marques, Alexandra P

2015-01-01

Tissue-engineered constructs made of biotechnology-derived materials have been preferred due to their chemical and physical composition, which offers both high versatility and a support to enclose/ incorporate relevant signaling molecules and/or genes known to therapeutically induce tissue repair. Herein, a critical overview of the impact of different biotechnology-derived materials, scaffolds, and recombinant signaling molecules over the behavior of cells, another element of tissue engineered constructs, as well its regulatory role in tissue regeneration and disease progression is given. Additionally, these tissue-engineered constructs evolved to three-dimensional (3D) tissue-like models that, as an advancement of two-dimensional standard culture methods, are expected to be a valuable tool in the field of drug discovery and pharmaceutical research. Despite the improved design and conception of current proposed 3D tissue-like models, advanced control systems to enable and accelerate streamlining and automation of the numerous labor-intensive steps intrinsic to the development of tissue-engineered constructs are still to be achieved. In this sense, this review intends to present the biotechnology- derived materials that are being explored in the field of tissue engineering to generate 3D tissue-analogues and briefly highlight their foremost breakthroughs in tissue regeneration and drug discovery. It also aims to reinforce that the crosstalk between tissue engineering and pharmaceutical biotechnology has been fostering the outcomes of tissue engineering approaches through the use of biotechnology-derived signaling molecules. Gene delivery/therapy is also discussed as a forefront area that represents another cross point between tissue engineering and pharmaceutical biotechnology, in which nucleic acids can be considered a "super pharmaceutical" to drive biological responses, including tissue regeneration.

Differential osteogenic activity of osteoprogenitor cells on HA and TCP/HA scaffold of tissue engineered bone.

PubMed

Ng, Angela M H; Tan, K K; Phang, M Y; Aziyati, O; Tan, G H; Isa, M R; Aminuddin, B S; Naseem, M; Fauziah, O; Ruszymah, B H I

2008-05-01

Biomaterial, an essential component of tissue engineering, serves as a scaffold for cell attachment, proliferation, and differentiation; provides the three dimensional (3D) structure and, in some applications, the mechanical strength required for the engineered tissue. Both synthetic and naturally occurring calcium phosphate based biomaterial have been used as bone fillers or bone extenders in orthopedic and reconstructive surgeries. This study aims to evaluate two popular calcium phosphate based biomaterial i.e., hydroxyapatite (HA) and tricalcium phosphate/hydroxyapatite (TCP/HA) granules as scaffold materials in bone tissue engineering. In our strategy for constructing tissue engineered bone, human osteoprogenitor cells derived from periosteum were incorporated with human plasma-derived fibrin and seeded onto HA or TCP/HA forming 3D tissue constructs and further maintained in osteogenic medium for 4 weeks to induce osteogenic differentiation. Constructs were subsequently implanted intramuscularly in nude mice for 8 weeks after which mice were euthanized and constructs harvested for evaluation. The differential cell response to the biomaterial (HA or TCP/HA) adopted as scaffold was illustrated by the histology of undecalcified constructs and evaluation using SEM and TEM. Both HA and TCP/HA constructs showed evidence of cell proliferation, calcium deposition, and collagen bundle formation albeit lesser in the former. Our findings demonstrated that TCP/HA is superior between the two in early bone formation and hence is the scaffold material of choice in bone tissue engineering. Copyright 2007 Wiley Periodicals, Inc.

In vitro engineering of fibrocartilage using CDMP1 induced dermal fibroblasts and polyglycolide.

PubMed

Zhao, Guiqing; Yin, Shuo; Liu, Guangpeng; Cen, Lian; Sun, Jian; Zhou, Heng; Liu, Wei; Cui, Lei; Cao, Yilin

2009-07-01

This study was designed to explore the feasibility of using cartilage-derived morphogenetic protein-1 (CDMP1) induced dermal fibroblasts (DFs) as seed cells and polyglycolide (PGA) as scaffold for fibrocartilage engineering. DFs isolated from canine were expanded and seeded on PGA scaffold to fabricate cell/scaffold constructs which were cultured with or without CDMP1. Proliferation and differentiation of DFs in different constructs were determined by DNA assay and glycosaminoglycan (GAG) production. Histological and immunohistochemical staining of the constructs after being in vitro cultured for 4 and 6 weeks were carried out to observe the fibrocartilage formation condition. The fibrocartilage-specific gene expression by cells in the constructs was analyzed by real-time PCR. It was shown that in the presence of CDMP1 the proliferation and GAG synthesis of DFs were significantly enhanced compared to those without CDMP1. Fibrocartilage-like tissue was formed in the CDMP1 induced construct after being cultured for 4 weeks, and it became more matured at 6 weeks as stronger staining for GAG and higher gene expression of collagen type II was observed. Since only weak staining for GAG and collagen type II was observed for the construct engineered without CDMP1, the induction effect on the fibrocartilage engineering can be ascertained when using DFs as seed cells. Furthermore, the potential of using DFs as seed cells to engineer fibrocartilage is substantiated and further study on using the engineered tissue to repair fibrocartilage defects is currently ongoing in our group.

A study of competence in mathematics and mechanics in an engineering curriculum

NASA Astrophysics Data System (ADS)

Munns, Andrew

2017-11-01

Professional bodies expect engineers to show competence in both mathematics and engineering topics such as mechanics, using their abilities in both of these to solve problems. Yet within engineering programmes there is a phenomenon known as 'The Mathematics Problem', with students not demonstrating understanding of the subject. This paper will suggest that students are constructing different concept images in engineering and mathematics, based on their perception of either the use or exchange-value for the topics. Using a mixed methods approach, the paper compares 10 different types of concept image constructed by students, which suggests that familiar procedural images are preferred in mathematics. In contrast strategic and conceptual images develop for mechanics throughout the years of the programme, implying that different forms of competence are being constructed by students between the two subjects. The paper argues that this difference is attributed to the perceived use-value of mechanics in the career of the engineer, compared to the exchange-value associated with mathematics. Questions are raised about the relevance of current definitions of competence given that some routine mathematical operations previously performed by engineers are now being replaced by technology, in the new world of work.

Combined chemical and structural signals of biomaterials synergistically activate cell-cell communications for improving tissue regeneration.

PubMed

Xu, Yachen; Peng, Jinliang; Dong, Xin; Xu, Yuhong; Li, Haiyan; Chang, Jiang

2017-06-01

Biomaterials are only used as carriers of cells in the conventional tissue engineering. Considering the multi-cell environment and active cell-biomaterial interactions in tissue regeneration process, in this study, structural signals of aligned electrospun nanofibers and chemical signals of bioglass (BG) ionic products in cell culture medium are simultaneously applied to activate fibroblast-endothelial co-cultured cells in order to obtain an improved skin tissue engineering construct. Results demonstrate that the combined biomaterial signals synergistically activate fibroblast-endothelial co-culture skin tissue engineering constructs through promotion of paracrine effects and stimulation of gap junctional communication between cells, which results in enhanced vascularization and extracellular matrix protein synthesis in the constructs. Structural signals of aligned electrospun nanofibers play an important role in stimulating both of paracrine and gap junctional communication while chemical signals of BG ionic products mainly enhance paracrine effects. In vivo experiments reveal that the activated skin tissue engineering constructs significantly enhance wound healing as compared to control. This study indicates the advantages of synergistic effects between different bioactive signals of biomaterials can be taken to activate communication between different types of cells for obtaining tissue engineering constructs with improved functions. Tissue engineering can regenerate or replace tissue or organs through combining cells, biomaterials and growth factors. Normally, for repairing a specific tissue, only one type of cells, one kind of biomaterials, and specific growth factors are used to support cell growth. In this study, we proposed a novel tissue engineering approach by simply using co-cultured cells and combined biomaterial signals. Using a skin tissue engineering model, we successfully proved that the combined biomaterial signals such as surface nanostructures and bioactive ions could synergistically stimulate the cell-cell communication in co-culture system through paracrine effects and gap junction activation, and regulated expression of growth factors and extracellular matrix proteins, resulting in an activated tissue engineering constructs that significantly enhanced skin regeneration. Copyright © 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

7 CFR 1724.32 - Inspection and certification of work order construction.

Code of Federal Regulations, 2013 CFR

2013-01-01

...) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE ELECTRIC ENGINEERING, ARCHITECTURAL SERVICES AND... construction. The provisions of this section apply to all borrower electric system facilities regardless of the... performed within 6 months of the completion of construction, and are performed by a licensed engineer...

7 CFR 1724.32 - Inspection and certification of work order construction.

Code of Federal Regulations, 2012 CFR

2012-01-01

...) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE ELECTRIC ENGINEERING, ARCHITECTURAL SERVICES AND... construction. The provisions of this section apply to all borrower electric system facilities regardless of the... performed within 6 months of the completion of construction, and are performed by a licensed engineer...

46 CFR 162.018-1 - Applicable specifications, and referenced material.

Code of Federal Regulations, 2012 CFR

2012-10-01

...) The ASME Code may be obtained from the American Society of Mechanical Engineers, United Engineering..., CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL ENGINEERING EQUIPMENT Safety Relief Valves, Liquefied... (Procedures Applicable to the Public) and Subpart 50.15 of Subchapter F (Marine Engineering) of this chapter...

46 CFR 162.018-1 - Applicable specifications, and referenced material.

Code of Federal Regulations, 2013 CFR

2013-10-01

...) The ASME Code may be obtained from the American Society of Mechanical Engineers, United Engineering..., CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL ENGINEERING EQUIPMENT Safety Relief Valves, Liquefied... (Procedures Applicable to the Public) and Subpart 50.15 of Subchapter F (Marine Engineering) of this chapter...

46 CFR 162.018-1 - Applicable specifications, and referenced material.

Code of Federal Regulations, 2010 CFR

2010-10-01

...) The ASME Code may be obtained from the American Society of Mechanical Engineers, United Engineering..., CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL ENGINEERING EQUIPMENT Safety Relief Valves, Liquefied... (Procedures Applicable to the Public) and Subpart 50.15 of Subchapter F (Marine Engineering) of this chapter...

46 CFR 162.018-1 - Applicable specifications, and referenced material.

Code of Federal Regulations, 2014 CFR

2014-10-01

...) The ASME Code may be obtained from the American Society of Mechanical Engineers, United Engineering..., CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL ENGINEERING EQUIPMENT Safety Relief Valves, Liquefied... (Procedures Applicable to the Public) and Subpart 50.15 of Subchapter F (Marine Engineering) of this chapter...

46 CFR 162.018-1 - Applicable specifications, and referenced material.

Code of Federal Regulations, 2011 CFR

2011-10-01

...) The ASME Code may be obtained from the American Society of Mechanical Engineers, United Engineering..., CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL ENGINEERING EQUIPMENT Safety Relief Valves, Liquefied... (Procedures Applicable to the Public) and Subpart 50.15 of Subchapter F (Marine Engineering) of this chapter...

Table-Top Robotics for Engineering Design

ERIC Educational Resources Information Center

Wilczynski, Vincent; Dixon, Gregg; Ford, Eric

2005-01-01

The Mechanical Engineering Section at the U.S. Coast Guard Academy has developed a comprehensive activity based course to introduce second year students to mechanical engineering design. The culminating design activity for the course requires students to design, construct and test robotic devices that complete engineering challenges. Teams of…

46 CFR 71.65-5 - Plans and specifications required for new construction.

Code of Federal Regulations, 2010 CFR

2010-10-01

... dioxide, foam, and sprinkling systems. (7) Supervised Patrol Route. (e) Marine engineering. (1) For plans required for marine engineering equipment and systems, see subchapter F (Marine Engineering) of this... equipment and systems, see subchapter J (Electrical Engineering) of this chapter. (2) [Reserved] (g...

Redesigning the Student Learning Approach through Personality Types and Pedagogies, A Case Study in an Undergraduate Engineering Course

ERIC Educational Resources Information Center

Fleischmann, Corinna; Nakagawa, Elizabeth; Kelley, Tyler

2016-01-01

As the National Science Foundation and engineers throughout the world seek to strengthen the future of the engineering profession, the Civil Engineering (CE) program at the United States Coast Guard Academy embodies this initiative with a student focused approach. One course in particular, Materials for Civil and Construction Engineers (CE…

Challenges for Engineering Design, Construction, and Maintenance of Infrastructure in Afghanistan

DTIC Science & Technology

2010-11-01

applied engineering expertise that collectively can solve challenging infra- structure problems. USACE-ERDC’s researchers and engineers are field...Development Center (ERDC) possesses a unique combination of basic research and applied engineering expertise that collectively can solve challenging...restoration, and other projects. The USACE Engineer Research and Development Center (ERDC) possesses a unique combination of basic research and applied

Safety in Construction Using Virtual Reality (SAVR): A Model for Labor Safety. Working Paper Series WP-022.

ERIC Educational Resources Information Center

Hadipriono, Fabian C.; And Others

An interactive training model called SAVR (Safety in Construction Using Virtual Reality) was developed to train construction students, novice engineers, and construction workers to prevent falls from scaffolding. The model was implemented in a graphics supercomputer, the ONYX Reality Engine2. The SAVR model provides trainees with an immersive,…

48 CFR 36.601-4 - Implementation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... engineering nature associated with design or construction of real property. (3) Other professional services of..., investigations, surveying and mapping, tests, evaluations, consultations, comprehensive planning, program management, conceptual designs, plans and specifications, value engineering, construction phase services...

48 CFR 36.601-4 - Implementation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... engineering nature associated with design or construction of real property. (3) Other professional services of..., investigations, surveying and mapping, tests, evaluations, consultations, comprehensive planning, program management, conceptual designs, plans and specifications, value engineering, construction phase services...

48 CFR 36.601-4 - Implementation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... engineering nature associated with design or construction of real property. (3) Other professional services of..., investigations, surveying and mapping, tests, evaluations, consultations, comprehensive planning, program management, conceptual designs, plans and specifications, value engineering, construction phase services...

48 CFR 36.601-4 - Implementation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... engineering nature associated with design or construction of real property. (3) Other professional services of..., investigations, surveying and mapping, tests, evaluations, consultations, comprehensive planning, program management, conceptual designs, plans and specifications, value engineering, construction phase services...

48 CFR 36.601-4 - Implementation.

Code of Federal Regulations, 2012 CFR

2012-10-01

... engineering nature associated with design or construction of real property. (3) Other professional services of..., investigations, surveying and mapping, tests, evaluations, consultations, comprehensive planning, program management, conceptual designs, plans and specifications, value engineering, construction phase services...

Construction engineering inspection direct cost survey.

DOT National Transportation Integrated Search

2014-07-01

The objective of the study was to provide a rationale to Georgia Department of Transportation : (GDOT) for Direct Costs in terms of salary and wages charged by qualified independent : contractors performing Construction Engineering Inspection (CEI) s...

14 CFR 23.1193 - Cowling and nacelle.

Code of Federal Regulations, 2012 CFR

2012-01-01

...) Each cowling must be constructed and supported so that it can resist any vibration, inertia, and air... engines must be designed and constructed so that with the landing gear retracted, a fire in the engine...

14 CFR 33.66 - Bleed air system.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Bleed air system. 33.66 Section 33.66... STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.66 Bleed air system. The engine must supply bleed air without adverse effect on the engine, excluding reduced thrust or power...

40 CFR 35.2114 - Value engineering.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Value engineering. 35.2114 Section 35... STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works § 35.2114 Value engineering. (a) If the project has not received Step 2 grant assistance the applicant shall conduct value engineering...

40 CFR 35.2114 - Value engineering.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Value engineering. 35.2114 Section 35... STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works § 35.2114 Value engineering. (a) If the project has not received Step 2 grant assistance the applicant shall conduct value engineering...

40 CFR 35.2114 - Value engineering.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Value engineering. 35.2114 Section 35... STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works § 35.2114 Value engineering. (a) If the project has not received Step 2 grant assistance the applicant shall conduct value engineering...

40 CFR 35.2114 - Value engineering.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Value engineering. 35.2114 Section 35... STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works § 35.2114 Value engineering. (a) If the project has not received Step 2 grant assistance the applicant shall conduct value engineering...

40 CFR 35.2114 - Value engineering.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Value engineering. 35.2114 Section 35... STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works § 35.2114 Value engineering. (a) If the project has not received Step 2 grant assistance the applicant shall conduct value engineering...

Construction of an Engineer's Notebook Rubric

ERIC Educational Resources Information Center

Kelley, Todd R.

2014-01-01

It is evident that there is a need for assessment instruments that measure design and engineering design skills, knowledge, and ways of design thinking. These student assessments must be authentic to engineering design practices and measure key elements of the engineering design process. Kelley (2011) presented a rationale to include…

46 CFR 91.55-5 - Plans and specifications required for new construction.

Code of Federal Regulations, 2010 CFR

2010-10-01

... systems. (e) Marine engineering. For plans required for marine engineering equipment and systems, see... electrical engineering, equipment and systems, see subchapter J (Electrical Engineering) of this chapter. (g... bottoms, etc., and including inboard and outboard profile. (b) Hull structure. 1 (1) *Inner Bottom Plating...

Temporal development of near-native functional properties and correlations with qMRI in self-assembling fibrocartilage treated with exogenous lysyl oxidase homolog 2.

PubMed

Hadidi, Pasha; Cissell, Derek D; Hu, Jerry C; Athanasiou, Kyriacos A

2017-12-01

Advances in cartilage tissue engineering have led to constructs with mechanical integrity and biochemical composition increasingly resembling that of native tissues. In particular, collagen cross-linking with lysyl oxidase has been used to significantly enhance the mechanical properties of engineered neotissues. In this study, development of collagen cross-links over time, and correlations with tensile properties, were examined in self-assembling neotissues. Additionally, quantitative MRI metrics were examined in relation to construct mechanical properties as well as pyridinoline cross-link content and other engineered tissue components. Scaffold-free meniscus fibrocartilage was cultured in the presence of exogenous lysyl oxidase, and assessed at multiple time points over 8weeks starting from the first week of culture. Engineered constructs demonstrated a 9.9-fold increase in pyridinoline content, reaching 77% of native tissue values, after 8weeks of culture. Additionally, engineered tissues reached 66% of the Young's modulus in the radial direction of native tissues. Further, collagen cross-links were found to correlate with tensile properties, contributing 67% of the tensile strength of engineered neocartilages. Finally, examination of quantitative MRI metrics revealed several correlations with mechanical and biochemical properties of engineered constructs. This study displays the importance of culture duration for collagen cross-link formation, and demonstrates the potential of quantitative MRI in investigating properties of engineered cartilages. This is the first study to demonstrate near-native cross-link content in an engineered tissue, and the first study to quantify pyridinoline cross-link development over time in a self-assembling tissue. Additionally, this work shows the relative contributions of collagen and pyridinoline to the tensile properties of collagenous tissue for the first time. Furthermore, this is the first investigation to identify a relationship between qMRI metrics and the pyridinoline cross-link content of an engineered collagenous tissue. Copyright © 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

Ultrasound Technologies for the Spatial Patterning of Cells and Extracellular Matrix Proteins and the Vascularization of Engineered Tissue

NASA Astrophysics Data System (ADS)

Garvin, Kelley A.

Technological advancements in the field of tissue engineering could save the lives of thousands of organ transplant patients who die each year while waiting for donor organs. Currently, two of the primary challenges preventing tissue engineers from developing functional replacement tissues and organs are the need to recreate complex cell and extracellular microenvironments and to vascularize the tissue to maintain cell viability and function. Ultrasound is a form of mechanical energy that can noninvasively and nondestructively interact with tissues at the cell and protein level. In this thesis, novel ultrasound-based technologies were developed for the spatial patterning of cells and extracellular matrix proteins and the vascularization of three-dimensional engineered tissue constructs. Acoustic radiation forces associated with ultrasound standing wave fields were utilized to noninvasively control the spatial organization of cells and cell-bound extracellular matrix proteins within collagen-based engineered tissue. Additionally, ultrasound induced thermal mechanisms were exploited to site-specifically pattern various extracellular matrix collagen microstructures within a single engineered tissue construct. Finally, ultrasound standing wave field technology was used to promote the rapid and extensive vascularization of three-dimensional tissue constructs. As such, the ultrasound technologies developed in these studies have the potential to provide the field of tissue engineering with novel strategies to spatially pattern cells and extracellular matrix components and to vascularize engineered tissue, and thus, could advance the fabrication of functional replacement tissues and organs in the field of tissue engineering.

Presentation on systems cluster research

NASA Technical Reports Server (NTRS)

Morgenthaler, George W.

1989-01-01

This viewgraph presentation presents an overview of systems cluster research performed by the Center for Space Construction. The goals of the research are to develop concepts, insights, and models for space construction and to develop systems engineering/analysis curricula for training future aerospace engineers. The following topics are covered: CSC systems analysis/systems engineering (SIMCON) model, CSC systems cluster schedule, system life-cycle, model optimization techniques, publications, cooperative efforts, and sponsored research.

58. Photographic copy of original construction plan (St. Paul Engineer's ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

58. Photographic copy of original construction plan (St. Paul Engineer's Office, Wabasha St. Bridge, Plan of Masonry, February 1899); south abutment - Wabasha Street Bridge, Spanning Mississippi River at Wabasha Street, Saint Paul, Ramsey County, MN

Railway project design and construction (CEE 411) course updates.

DOT National Transportation Integrated Search

2017-01-20

Course CEE 411 "Railway Project Design and Construction" is a cornerstone of the railway : engineering education program developed by the Rail Transportation and Engineering Center : (RailTEC) at the University of Illinois at Urbana-Champaign (UIUC)....

Vascularized Bone Tissue Engineering: Approaches for Potential Improvement

PubMed Central

Nguyen, Lonnissa H.; Annabi, Nasim; Nikkhah, Mehdi; Bae, Hojae; Binan, Loïc; Park, Sangwon; Kang, Yunqing

2012-01-01

Significant advances have been made in bone tissue engineering (TE) in the past decade. However, classical bone TE strategies have been hampered mainly due to the lack of vascularization within the engineered bone constructs, resulting in poor implant survival and integration. In an effort toward clinical success of engineered constructs, new TE concepts have arisen to develop bone substitutes that potentially mimic native bone tissue structure and function. Large tissue replacements have failed in the past due to the slow penetration of the host vasculature, leading to necrosis at the central region of the engineered tissues. For this reason, multiple microscale strategies have been developed to induce and incorporate vascular networks within engineered bone constructs before implantation in order to achieve successful integration with the host tissue. Previous attempts to engineer vascularized bone tissue only focused on the effect of a single component among the three main components of TE (scaffold, cells, or signaling cues) and have only achieved limited success. However, with efforts to improve the engineered bone tissue substitutes, bone TE approaches have become more complex by combining multiple strategies simultaneously. The driving force behind combining various TE strategies is to produce bone replacements that more closely recapitulate human physiology. Here, we review and discuss the limitations of current bone TE approaches and possible strategies to improve vascularization in bone tissue substitutes. PMID:22765012

Saturn Apollo Program

NASA Image and Video Library

1968-06-01

This photograph depicts a test firing of an F-1 engine at the F-1 engine test stand in the west test area of the Marshall Space Flight Center. This engine produced 1,500,000 pounds of thrust using liquid oxygen and RP-1, which is a derivative of kerosene. The F-1 engine test stand was constructed in 1963 to assist in the development of the F-1 engine.

Quiet Clean Short-haul Experimental Engine (QCSEE) under-the-wing engine simulation report

NASA Technical Reports Server (NTRS)

1977-01-01

Hybrid computer simulations of the under-the-wing engine were constructed to develop the dynamic design of the controls. The engine and control system includes a variable pitch fan and a digital electronic control. Simulation results for throttle bursts from 62 to 100 percent net thrust predict that the engine will accelerate 62 to 95 percent net thrust in one second.

Management and integration of engineering and construction activities: Lessons learned from the AP1000{sup R} nuclear power plant China project

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCullough, M. C.; Ebeling-Koning, D.; Evans, M. C.

2012-07-01

The lessons learned during the early phase of design engineering and construction activities for the AP1000 China Project can be applied to any project involving multiple disciplines and multiple organizations. Implementation of a first-of-a-kind design to directly support construction activities utilizing resources assigned to design development and design delivery creates challenges with prioritization of activities, successful closure of issues, and communication between site organizations and the home office. To ensure successful implementation, teams were assigned and developed to directly support construction activities including prioritization of activities, site communication and ensuring closure of site emergent issues. By developing these teams, themore » organization is better suited to meet the demands of the construction schedule while continuing with design evolution of a standard plant and engineering delivery for multiple projects. For a successful project, proper resource utilization and prioritization are key for overcoming obstacles and ensuring success of the engineering organization. (authors)« less

Opportunities for Multidisciplinary Research in Partnership with Rock Engineers at the Deep Underground Science and Engineering Laboratory

NASA Astrophysics Data System (ADS)

Laughton, C.

2008-12-01

For the last half century the physics community has increasingly turned to the use of underground space to conduct basic research. The community is currently planning to conduct a new generation of underground experiments at the Deep Underground Science and Engineering Laboratory (DUSEL). DUSEL will be constructed within the footprint of the defunct Homestake Gold Mine, located in Lead, South Dakota. Physics proposals call for the construction of new caverns in which to conduct major new experiments. Some of the proposed laboratory facilities will be significantly larger and deeper than any previously constructed. The talk will highlight possible opportunities for integrating multi-disciplinary research in to the cavern construction program, and will stress the need to work closely with design and construction contractors to ensure that research goals can be achieve with minimal impact on project work. The constructors of large caverns should be particularly receptive to, and encouraging of geoscience research that could improve the engineering characterization of the rock mass. An improved understanding of the rock mass, as the host construction material, would result in a more reliable cavern design and construction process, and a reduced construction risk to the Project.

The trajectories of Prevention through Design in construction.

PubMed

Toole, T Michael; Gambatese, John

2008-01-01

Construction Hazards Prevention through Design (CHPtD) is a process in which engineers and architects explicitly consider the safety of construction workers during the design process. Although articles on CHPtD have appeared in top construction journals, the literature has not addressed technical principles underlying CHPtD to help designers better perform CHPtD, to facilitate the development of additional CHPtD tools, and to predict the future path of CHPtD. This theoretical paper uses the existing literature on CHPtD and current action research associated with several CHPtD workgroups to analyze how CHPtD will likely evolve over the coming decades. There are four trajectories along which CHPtD will progress. (a) Designs will increasingly facilitate prefabricated construction; (b) designers will increasingly choose materials and systems that are inherently safer than alternatives; (c) designers will increasingly perform construction engineering; and (d) designers will increasingly apply spatial considerations to reduce worker hazards. By understanding how CHPtD may be manifested in the engineering-procurement-construction (EPC) industry, practitioners can better prepare for adopting CHPtD within their organizations and construction and engineering educators can better prepare their graduates to perform CHPtD.

The "Difference" in Babbage's Difference Engine.

ERIC Educational Resources Information Center

Crowley, Mary L.

1985-01-01

Discoveries of Charles Babbage in the 1800s are described. Origins of the difference engine, his calculating machine, the principles of computation applied to tables, and the design and construction of his engine are included. (MNS)

Recent Progress on Systems and Synthetic Biology Approaches to Engineer Fungi As Microbial Cell Factories.

PubMed

Amores, Gerardo Ruiz; Guazzaroni, María-Eugenia; Arruda, Letícia Magalhães; Silva-Rocha, Rafael

2016-04-01

Filamentous fungi are remarkable organisms naturally specialized in deconstructing plant biomass and this feature has a tremendous potential for biofuel production from renewable sources. The past decades have been marked by a remarkable progress in the genetic engineering of fungi to generate industry-compatible strains needed for some biotech applications. In this sense, progress in this field has been marked by the utilization of high-throughput techniques to gain deep understanding of the molecular machinery controlling the physiology of these organisms, starting thus the Systems Biology era of fungi. Additionally, genetic engineering has been extensively applied to modify wellcharacterized promoters in order to construct new expression systems with enhanced performance under the conditions of interest. In this review, we discuss some aspects related to significant progress in the understating and engineering of fungi for biotechnological applications, with special focus on the construction of synthetic promoters and circuits in organisms relevant for industry. Different engineering approaches are shown, and their potential and limitations for the construction of complex synthetic circuits in these organisms are examined. Finally, we discuss the impact of engineered promoter architecture in the single-cell behavior of the system, an often-neglected relationship with a tremendous impact in the final performance of the process of interest. We expect to provide here some new directions to drive future research directed to the construction of high-performance, engineered fungal strains working as microbial cell factories.

14 CFR 25.865 - Fire protection of flight controls, engine mounts, and other flight structure.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Design and Construction Fire Protection § 25.865 Fire protection of flight controls, engine mounts, and other flight structure. Essential flight controls, engine mounts, and other flight structures located in... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Fire protection of flight controls, engine...

14 CFR 25.865 - Fire protection of flight controls, engine mounts, and other flight structure.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Design and Construction Fire Protection § 25.865 Fire protection of flight controls, engine mounts, and other flight structure. Essential flight controls, engine mounts, and other flight structures located in... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Fire protection of flight controls, engine...

14 CFR 25.865 - Fire protection of flight controls, engine mounts, and other flight structure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Design and Construction Fire Protection § 25.865 Fire protection of flight controls, engine mounts, and other flight structure. Essential flight controls, engine mounts, and other flight structures located in... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Fire protection of flight controls, engine...

14 CFR 25.865 - Fire protection of flight controls, engine mounts, and other flight structure.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Design and Construction Fire Protection § 25.865 Fire protection of flight controls, engine mounts, and other flight structure. Essential flight controls, engine mounts, and other flight structures located in... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Fire protection of flight controls, engine...

14 CFR 25.865 - Fire protection of flight controls, engine mounts, and other flight structure.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Design and Construction Fire Protection § 25.865 Fire protection of flight controls, engine mounts, and other flight structure. Essential flight controls, engine mounts, and other flight structures located in... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Fire protection of flight controls, engine...

30 CFR 36.24 - Engine joints.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Engine joints. 36.24 Section 36.24 Mineral... Construction and Design Requirements § 36.24 Engine joints. (a) Cylinder head. The joint between the cylinder head and block of the engine shall be fitted with a metal or metal-clad gasket satisfactory to MSHA...

7 CFR 1710.253 - Engineering and cost studies-addition of generation capacity.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 11 2014-01-01 2014-01-01 false Engineering and cost studies-addition of generation... TO ELECTRIC LOANS AND GUARANTEES Construction Work Plans and Related Studies § 1710.253 Engineering... engineering and cost studies as specified by RUS. The studies shall cover a period from the beginning of the...

168. ARAIV Index of drawings prepared by Norman Engineering Company ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

168. ARA-IV Index of drawings prepared by Norman Engineering Company in preparation for construction of ARA-IV. Norman Engineering Company 961-area/ML-1index. Date: March 1961. Ineel index code no. 066-9999-90-613-102731. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

7 CFR 1710.253 - Engineering and cost studies-addition of generation capacity.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 11 2012-01-01 2012-01-01 false Engineering and cost studies-addition of generation... TO ELECTRIC LOANS AND GUARANTEES Construction Work Plans and Related Studies § 1710.253 Engineering... engineering and cost studies as specified by RUS. The studies shall cover a period from the beginning of the...

7 CFR 1710.253 - Engineering and cost studies-addition of generation capacity.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 11 2010-01-01 2010-01-01 false Engineering and cost studies-addition of generation... TO ELECTRIC LOANS AND GUARANTEES Construction Work Plans and Related Studies § 1710.253 Engineering... engineering and cost studies as specified by RUS. The studies shall cover a period from the beginning of the...

7 CFR 1710.253 - Engineering and cost studies-addition of generation capacity.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 11 2013-01-01 2013-01-01 false Engineering and cost studies-addition of generation... TO ELECTRIC LOANS AND GUARANTEES Construction Work Plans and Related Studies § 1710.253 Engineering... engineering and cost studies as specified by RUS. The studies shall cover a period from the beginning of the...

7 CFR 1710.253 - Engineering and cost studies-addition of generation capacity.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 11 2011-01-01 2011-01-01 false Engineering and cost studies-addition of generation... TO ELECTRIC LOANS AND GUARANTEES Construction Work Plans and Related Studies § 1710.253 Engineering... engineering and cost studies as specified by RUS. The studies shall cover a period from the beginning of the...

30 CFR 36.24 - Engine joints.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Engine joints. 36.24 Section 36.24 Mineral... Construction and Design Requirements § 36.24 Engine joints. (a) Cylinder head. The joint between the cylinder head and block of the engine shall be fitted with a metal or metal-clad gasket satisfactory to MSHA...

30 CFR 36.24 - Engine joints.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Engine joints. 36.24 Section 36.24 Mineral... Construction and Design Requirements § 36.24 Engine joints. (a) Cylinder head. The joint between the cylinder head and block of the engine shall be fitted with a metal or metal-clad gasket satisfactory to MSHA...

30 CFR 36.24 - Engine joints.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Engine joints. 36.24 Section 36.24 Mineral... Construction and Design Requirements § 36.24 Engine joints. (a) Cylinder head. The joint between the cylinder head and block of the engine shall be fitted with a metal or metal-clad gasket satisfactory to MSHA...

30 CFR 36.24 - Engine joints.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Engine joints. 36.24 Section 36.24 Mineral... Construction and Design Requirements § 36.24 Engine joints. (a) Cylinder head. The joint between the cylinder head and block of the engine shall be fitted with a metal or metal-clad gasket satisfactory to MSHA...

Educational Horsepower: Engine Design and Construction in the Classroom

ERIC Educational Resources Information Center

Christensen, Brad

2007-01-01

Engines, in their many forms and functions, have had a tremendous impact on society and the environment. It is hard for the contemporary student to fathom a world without trains, cars, trucks, powerboats, and airplanes. With the fascination, history, impacts, and importance of engines to modern society, it is only natural that engine technology…

Engineering Parameters in Bioreactor's Design: A Critical Aspect in Tissue Engineering

PubMed Central

Amoabediny, Ghassem; Pouran, Behdad; Tabesh, Hadi; Shokrgozar, Mohammad Ali; Haghighipour, Nooshin; Khatibi, Nahid; Mottaghy, Khosrow; Zandieh-Doulabi, Behrouz

2013-01-01

Bioreactors are important inevitable part of any tissue engineering (TE) strategy as they aid the construction of three-dimensional functional tissues. Since the ultimate aim of a bioreactor is to create a biological product, the engineering parameters, for example, internal and external mass transfer, fluid velocity, shear stress, electrical current distribution, and so forth, are worth to be thoroughly investigated. The effects of such engineering parameters on biological cultures have been addressed in only a few preceding studies. Furthermore, it would be highly inefficient to determine the optimal engineering parameters by trial and error method. A solution is provided by emerging modeling and computational tools and by analyzing oxygen, carbon dioxide, and nutrient and metabolism waste material transports, which can simulate and predict the experimental results. Discovering the optimal engineering parameters is crucial not only to reduce the cost and time of experiments, but also to enhance efficacy and functionality of the tissue construct. This review intends to provide an inclusive package of the engineering parameters together with their calculation procedure in addition to the modeling techniques in TE bioreactors. PMID:24000327

Engineering parameters in bioreactor's design: a critical aspect in tissue engineering.

PubMed

Salehi-Nik, Nasim; Amoabediny, Ghassem; Pouran, Behdad; Tabesh, Hadi; Shokrgozar, Mohammad Ali; Haghighipour, Nooshin; Khatibi, Nahid; Anisi, Fatemeh; Mottaghy, Khosrow; Zandieh-Doulabi, Behrouz

2013-01-01

Bioreactors are important inevitable part of any tissue engineering (TE) strategy as they aid the construction of three-dimensional functional tissues. Since the ultimate aim of a bioreactor is to create a biological product, the engineering parameters, for example, internal and external mass transfer, fluid velocity, shear stress, electrical current distribution, and so forth, are worth to be thoroughly investigated. The effects of such engineering parameters on biological cultures have been addressed in only a few preceding studies. Furthermore, it would be highly inefficient to determine the optimal engineering parameters by trial and error method. A solution is provided by emerging modeling and computational tools and by analyzing oxygen, carbon dioxide, and nutrient and metabolism waste material transports, which can simulate and predict the experimental results. Discovering the optimal engineering parameters is crucial not only to reduce the cost and time of experiments, but also to enhance efficacy and functionality of the tissue construct. This review intends to provide an inclusive package of the engineering parameters together with their calculation procedure in addition to the modeling techniques in TE bioreactors.

The Local Construction of the Asymmetrical Power Relationship in Teamwork among Engineers

ERIC Educational Resources Information Center

Vickers, Caroline H.

2010-01-01

The purpose of this article is to examine local, interactional processes associated with the construction of power asymmetries in collaborative teamwork among engineering students. To explore the construction of power asymmetries at the micro-interactional level, this article examines a corpus consisting of about 150,000 words in which seven teams…

Construction Site Environmental Impact in Civil Engineering Education

ERIC Educational Resources Information Center

Teixeira, Jose M. Cardoso

2005-01-01

The environmental impact of construction activity has gained increasing importance in the last few years and become a key subject for civil engineering education. A survey of Portuguese higher education institutions shows that concern with this topic is mostly directed at the impact of large construction projects and especially focused on their…

78 FR 23837 - Cranes and Derricks in Construction: Underground Construction and Demolition

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-23

... report here the results for the entire heavy-and-civil engineering sector and the entire site... in this final rule because employers included in the heavy-and-civil engineering sector, or the site... final rule. This final rule affects two construction sectors: NAICS 237990 (Other Heavy and Civil...

Study on energy consumption evaluation of mountainous highway based on LCA

NASA Astrophysics Data System (ADS)

Fei, Lunlin; Zhang, Qi; Xie, Yongqing

2017-06-01

For the system to understand the road construction energy consumption process, this paper selects a typical mountainous highway in the south, using the theory and method of Life Cycle Assessment (LCA) to quantitatively study the energy consumption of the whole process of highway raw materials production, construction and operation. The results show that the energy consumption in the raw material production stage is the highest, followed by the highway operation and construction stage. The energy consumption per unit of tunnel engineering, bridge engineering, roadbed engineering and pavement engineering in the construction phase are 2279.00 tce, 1718.07 tce, 542.19 tce and 34.02 tce, and in operational phase, 85.44% of electricity consumption comes from tunnel ventilation and lighting. Therefore, in the bridge and tunnel construction process, we should promote energy-saving innovation of the construction technology and mechanical equipment, and further strengthen the research and development of tunnel ventilation, lighting energy-saving equipment and intelligent control technology, which will help significantly reduce the energy consumption and greenhouse gas emissions of the life cycle of highway.

Enhancing Knowledge Sharing Management Using BIM Technology in Construction

PubMed Central

Ho, Shih-Ping; Tserng, Hui-Ping

2013-01-01

Construction knowledge can be communicated and reused among project managers and jobsite engineers to alleviate problems on a construction jobsite and reduce the time and cost of solving problems related to constructability. This paper proposes a new methodology for the sharing of construction knowledge by using Building Information Modeling (BIM) technology. The main characteristics of BIM include illustrating 3D CAD-based presentations and keeping information in a digital format and facilitation of easy updating and transfer of information in the BIM environment. Using the BIM technology, project managers and engineers can gain knowledge related to BIM and obtain feedback provided by jobsite engineers for future reference. This study addresses the application of knowledge sharing management using BIM technology and proposes a BIM-based Knowledge Sharing Management (BIMKSM) system for project managers and engineers. The BIMKSM system is then applied in a selected case study of a construction project in Taiwan to demonstrate the effectiveness of sharing knowledge in the BIM environment. The results demonstrate that the BIMKSM system can be used as a visual BIM-based knowledge sharing management platform by utilizing the BIM technology. PMID:24723790

Enhancing knowledge sharing management using BIM technology in construction.

PubMed

Ho, Shih-Ping; Tserng, Hui-Ping; Jan, Shu-Hui

2013-01-01

Construction knowledge can be communicated and reused among project managers and jobsite engineers to alleviate problems on a construction jobsite and reduce the time and cost of solving problems related to constructability. This paper proposes a new methodology for the sharing of construction knowledge by using Building Information Modeling (BIM) technology. The main characteristics of BIM include illustrating 3D CAD-based presentations and keeping information in a digital format and facilitation of easy updating and transfer of information in the BIM environment. Using the BIM technology, project managers and engineers can gain knowledge related to BIM and obtain feedback provided by jobsite engineers for future reference. This study addresses the application of knowledge sharing management using BIM technology and proposes a BIM-based Knowledge Sharing Management (BIMKSM) system for project managers and engineers. The BIMKSM system is then applied in a selected case study of a construction project in Taiwan to demonstrate the effectiveness of sharing knowledge in the BIM environment. The results demonstrate that the BIMKSM system can be used as a visual BIM-based knowledge sharing management platform by utilizing the BIM technology.

10 CFR 609.12 - Project Costs.

Code of Federal Regulations, 2011 CFR

2011-01-01

... incurred in the design, engineering, financing, construction, startup, commissioning and shakedown of the... rental of real property, including engineering fees, surveys, title insurance, recording fees, and legal... transportation for facility design, construction, startup, commissioning and shakedown; (3) Costs of equipment...

10 CFR 609.12 - Project Costs.

Code of Federal Regulations, 2012 CFR

2012-01-01

... incurred in the design, engineering, financing, construction, startup, commissioning and shakedown of the... rental of real property, including engineering fees, surveys, title insurance, recording fees, and legal... transportation for facility design, construction, startup, commissioning and shakedown; (3) Costs of equipment...

10 CFR 609.12 - Project Costs.

Code of Federal Regulations, 2013 CFR

2013-01-01

... incurred in the design, engineering, financing, construction, startup, commissioning and shakedown of the... rental of real property, including engineering fees, surveys, title insurance, recording fees, and legal... transportation for facility design, construction, startup, commissioning and shakedown; (3) Costs of equipment...

10 CFR 609.12 - Project Costs.

Code of Federal Regulations, 2010 CFR

2010-01-01

... incurred in the design, engineering, financing, construction, startup, commissioning and shakedown of the... rental of real property, including engineering fees, surveys, title insurance, recording fees, and legal... transportation for facility design, construction, startup, commissioning and shakedown; (3) Costs of equipment...

10 CFR 609.12 - Project Costs.

Code of Federal Regulations, 2014 CFR

2014-01-01

... incurred in the design, engineering, financing, construction, startup, commissioning and shakedown of the... rental of real property, including engineering fees, surveys, title insurance, recording fees, and legal... transportation for facility design, construction, startup, commissioning and shakedown; (3) Costs of equipment...

The influence of construct scale on the composition and functional properties of cartilaginous tissues engineered using bone marrow-derived mesenchymal stem cells.

PubMed

Buckley, Conor T; Meyer, Eric G; Kelly, Daniel J

2012-02-01

Engineering cartilaginous tissue of a scale necessary to treat defects observed clinically is a well-documented challenge in the field of cartilage tissue engineering. The objective of this study was to determine how the composition and mechanical properties of cartilaginous tissues that are engineered by using bone marrow-derived mesenchymal stem cells (MSCs) depend on the scale of the construct. Porcine bone marrow-derived MSCs were encapsulated in agarose hydrogels, and constructs of different cylindrical geometries (Ø4×1.5 mm; Ø5×3 mm; Ø6×4.5 mm; Ø8×4.5 mm) were fabricated and maintained in a chemically defined serum-free medium supplemented with transforming growth factor-β3 for 42 days. Total sulfated glycosaminoglycan (sGAG) accumulation by day 42 increased from 0.14% w/w to 0.88% w/w as the construct geometry increased from Ø4×1.5 to Ø8×4.5 mm, with collagen accumulation increasing from 0.31% w/w to 1.62% w/w. This led to an increase in the dynamic modulus from 90.81 to 327.51 kPa as the engineered tissue increased in scale from Ø4×1.5 to Ø8×4.5 mm. By decreasing the external oxygen tension from 20% to 5%, it was possible to achieve these higher levels of mechanical functionality in the smaller engineered tissues. Constructs were then sectioned into smaller subregions to quantify the spatial accumulation of extracellular matrix components, and a model of oxygen diffusion and consumption was used to predict spatial gradients in oxygen concentration throughout the construct. sGAG accumulation was always highest in regions where oxygen concentration was predicted to be lowest. In addition, as the size of the engineered construct increased, different regions of the construct preferentially supported either sGAG or collagen accumulation, thus suggesting that gradients in regulatory factors other than oxygen were playing a role in determining levels of collagen synthesis. The identification of such factors and the means to control their spatial concentration within developing tissues represents a central challenge in engineering large cartilaginous grafts.

Conceptional Considerations to Energy Balance and Global Warming Potential of Soil Bioengineering Structures

NASA Astrophysics Data System (ADS)

von der Thannen, Magdalena; Paratscha, Roman; Smutny, Roman; Lampalzer, Thomas; Strauss, Alfred; Rauch, Hans Peter

2016-04-01

Nowadays there is a high demand on engineering solutions considering not only technical aspects but also ecological and aesthetic values. In this context soil bioengineering techniques are often used as standalone solutions or in combination with conventional engineering structures. It is a construction technique that uses biological components for hydraulic and civil engineering solutions. In general it pursues the same objectives as conventional civil engineering structures. Currently the used assessment methods for soil bioengineering structures are referencing technically, ecologically and socio-economically. In a modern engineering approach additionally, environmental impacts and potential added values should be considered. The research project E-Protect aims at developing Environmental Life Cycle Assessment (LCA) models for this special field of alpine protective constructions. Both, the Cumulative Energy Demand (CED) and the Global Warming Potential (GWP) should be considered in an Environmental LCA over the whole life cycle of an engineering structure. The life cycle itself can be divided into three phases: the construction phase, the use phase and the end of life phase. The paper represents a concept to apply an Environmental LCA model for soil bioengineering structures. Beside the construction phase of these structures particular attention will be given to the use phase. It is not only important in terms of engineering effects but also plays an important role for positive carbon footprint due to the growing plants of soil bioengineering structures in contrast to conventional structures. Innovative Environmental LCA models will be applied to soil bioengineering structures which provide a new transparency for the responsible planners and stakeholders, by pointing out the total consumption of resources in all construction phases and components.

Reconstruction of structure and function in tissue engineering of solid organs: Toward simulation of natural development based on decellularization.

PubMed

Zheng, Chen-Xi; Sui, Bing-Dong; Hu, Cheng-Hu; Qiu, Xin-Yu; Zhao, Pan; Jin, Yan

2018-04-27

Failure of solid organs, such as the heart, liver, and kidney, remains a major cause of the world's mortality due to critical shortage of donor organs. Tissue engineering, which uses elements including cells, scaffolds, and growth factors to fabricate functional organs in vitro, is a promising strategy to mitigate the scarcity of transplantable organs. Within recent years, different construction strategies that guide the combination of tissue engineering elements have been applied in solid organ tissue engineering and have achieved much progress. Most attractively, construction strategy based on whole-organ decellularization has become a popular and promising approach, because the overall structure of extracellular matrix can be well preserved. However, despite the preservation of whole structure, the current constructs derived from decellularization-based strategy still perform partial functions of solid organs, due to several challenges, including preservation of functional extracellular matrix structure, implementation of functional recellularization, formation of functional vascular network, and realization of long-term functional integration. This review overviews the status quo of solid organ tissue engineering, including both advances and challenges. We have also put forward a few techniques with potential to solve the challenges, mainly focusing on decellularization-based construction strategy. We propose that the primary concept for constructing tissue-engineered solid organs is fabricating functional organs based on intact structure via simulating the natural development and regeneration processes. Copyright © 2018 John Wiley & Sons, Ltd.

Pathfinder

NASA Image and Video Library

1997-06-04

A close-up view of Bantam duration testing of the 40K Fastrac II Engine for X-34 at Marshall Space Flight Center's (MSFC) test stand 116. The Bantam test refers to the super lightweight engines of the Fastrac program. The engines were designed as part of the low cost X-34 Reusable Launch Vehicle (RLV). The testing of these engines at MSFC allowed the engineers to determine the capabilities of these engines and the metal alloys that were used in their construction. The Fastrac and X-34 programs were cancelled in 2001.

A forecast of bridge engineering, 1980-2000.

DOT National Transportation Integrated Search

1979-01-01

A three-pronged study was undertaken to forecast the nature of bridge engineering and construction for the years 1980 to 2000. First, the history of bridge engineering was explored to extrapolate likely future developments. Second, a detailed questio...

Micro-cogeneration units based on Stirling engine for heating and their real operation

NASA Astrophysics Data System (ADS)

Čierny, Jaroslav; Patsch, Marek

2014-08-01

This article was deal with micro-cogeneration units based on Stirling engine. We watched problematic of real working Stirling engine. The article also contain hookup of unit constructed at University of Zilina.

Recent Efforts and Experiments in the Construction of Aviation Engines

NASA Technical Reports Server (NTRS)

SCHWAGER

1920-01-01

It became evident during World War I that ever-increasing demands were being placed on the mean power of aircraft engines as a result of the increased on board equipment and the demands of aerial combat. The need was for increased climbing efficiency and climbing speed. The response to these demands has been in terms of lightweight construction and the adaptation of the aircraft engine to the requirements of its use. Discussed here are specific efforts to increase flying efficiency, such as reduction of the number of revolutions of the propeller from 1400 to about 900 r.p.m. through the use of a reduction gear, increasing piston velocity, locating two crankshafts in one gear box, and using the two-cycle stroke. Also discussed are improvements in the transformation of fuel energy into engine power, the raising of compression ratios, the use of super-compression with carburetors constructed for high altitudes, the use of turbo-compressors, rotary engines, and the use of variable pitch propellers.

New business opportunity: Green field project with new technology

NASA Astrophysics Data System (ADS)

Lee, Seung Jae; Woo, Jong Hun; Shin, Jong Gye

2014-06-01

Since 2009 of global financial crisis, shipbuilding industry has undergone hard times seriously. After such a long depression, the latest global shipping market index shows that the economic recovery of global shipbuilding market is underway. Especially, nations with enormous resources are going to increase their productivity or expanding their shipyards to accommodate a large amount of orders expected in the near future. However, few commercial projects have been carried out for the practical shipyard layout designs even though those can be good commercial opportunities for shipbuilding engineers. Shipbuilding starts with a shipyard construction with a large scale investment initially. Shipyard design and the equipment layout problem, which is directly linked to the productivity of ship production, is an important issue in the production planning of mass production of ships. In many cases, shipbuilding yard design has relied on the experience of the internal engineer, resulting in sporadic and poorly organized processes. Consequently, economic losses and the trial and error involved in such a design process are inevitable problems. The starting point of shipyard construction is to design a shipyard layout. Four kinds of engineering parts required for the shipyard layout design and construction. Those are civil engineering, building engineering, utility engineering and production layout engineering. Among these parts, production layout engineering is most important because its result is used as a foundation of the other engineering parts, and also, determines the shipyard capacity in the shipyard lifecycle. In this paper, the background of shipbuilding industry is explained in terms of engineering works for the recognition of the macro trend. Nextly, preliminary design methods and related case study is introduced briefly by referencing the previous research. Lastly, the designed work of layout design is validated using the computer simulation technology.

48 CFR 36.102 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS General 36.102 Definitions. As used in this part— Contract is intended to refer to a contract for construction or a contract for architect-engineer services..., structural, electrical, mechanical, and fire protection), producing the technical specifications and drawings...

48 CFR 36.102 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS General 36.102 Definitions. As used in this part— Contract is intended to refer to a contract for construction or a contract for architect-engineer services..., structural, electrical, mechanical, and fire protection), producing the technical specifications and drawings...

48 CFR 36.102 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS General 36.102 Definitions. As used in this part— Contract is intended to refer to a contract for construction or a contract for architect-engineer services..., structural, electrical, mechanical, and fire protection), producing the technical specifications and drawings...

48 CFR 36.102 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS General 36.102 Definitions. As used in this part— Contract is intended to refer to a contract for construction or a contract for architect-engineer services..., structural, electrical, mechanical, and fire protection), producing the technical specifications and drawings...

48 CFR 36.102 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS General 36.102 Definitions. As used in this part— Contract is intended to refer to a contract for construction or a contract for architect-engineer services..., structural, electrical, mechanical, and fire protection), producing the technical specifications and drawings...

76 FR 35424 - Information Collection Requirements; Defense Federal Acquisition Regulation Supplement...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-17

... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System Information Collection Requirements; Defense Federal Acquisition Regulation Supplement; Construction and Architect-Engineer Contracts AGENCY..., Construction and Architect-Engineer Contracts, and Related Clauses at DFARS 252.236; OMB Control Number 0704...

The hard start phenomena in hypergolic engines. Volume 5: RCS engine deformation and destruct tests

NASA Technical Reports Server (NTRS)

Miron, Y.; Perlee, H. E.

1974-01-01

Tests were conducted to determine the causes of Apollo Reaction Control (RCS) engine failures. Stainless steel engines constructed for use in the destructive tests are described. The tests conducted during the three phase investigation are discussed. It was determined that the explosive reaction that destroys the RCS engines occurs at the time of engine ignition and is apparently due to either the detonation of the heterogeneous constituents of the rocket engine, consisting primarily of unreacted propellant droplets and vapors, and/or the detonation of explosive materials accumulated on the engine walls from previous pulses. Photographs of the effects of explosions on the simulated RCS engines are provided.

14 CFR 33.73 - Power or thrust response.

Code of Federal Regulations, 2010 CFR

2010-01-01

....73 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.73 Power or... aircraft, without overtemperature, surge, stall, or other detrimental factors occurring to the engine...

14 CFR 33.73 - Power or thrust response.

Code of Federal Regulations, 2011 CFR

2011-01-01

....73 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.73 Power or... aircraft, without overtemperature, surge, stall, or other detrimental factors occurring to the engine...

14 CFR 33.75 - Safety analysis.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: AIRCRAFT ENGINES Design and Construction; Turbine Aircraft Engines § 33.75 Safety analysis. (a) (1) The applicant must analyze the engine, including the control system, to assess the likely...

The Use of Executive Control Processes in Engineering Design by Engineering Students and Professional Engineers

ERIC Educational Resources Information Center

Dixon, Raymond A.; Johnson, Scott D.

2012-01-01

A cognitive construct that is important when solving engineering design problems is executive control process, or metacognition. It is a central feature of human consciousness that enables one "to be aware of, monitor, and control mental processes." The framework for this study was conceptualized by integrating the model for creative design, which…

Aeronautical Engineering: A Continuing Bibliography with indexes

NASA Technical Reports Server (NTRS)

1984-01-01

This bibliography lists 426 reports, articles and other documents introduced into the NASA scientific and technical information system in August 1984. Reports are cited in the area of Aeronautical Engineering. The coverage includes documents on the engineering and theoretical aspects of design, construction, evaluation, testing operation and performance of aircraft (including aircraft engines) and associated components, equipment and systems.

Students' Awareness and Perceptions of Learning Engineering: Content and Construct Validation of an Instrument

ERIC Educational Resources Information Center

Duncan-Wiles, Daphne S.

2012-01-01

With the recent addition of engineering to most K-12 testable state standards, efficient and comprehensive instruments are needed to assess changes in student knowledge and perceptions of engineering. In this study, I developed the Students' Awareness and Perceptions of Learning Engineering (STAPLE) instrument to quantitatively measure fourth…

Aeronautical engineering. A continuing bibliography with indexes, supplement 127, October 1980

NASA Technical Reports Server (NTRS)

1980-01-01

A bibliography containing 431 abstracts addressing various topics in aeronautical engineering is given. The coverage includes engineering and theoretical aspects of design. construction, evaluation, testing, operation, and performance of aircraft (including aircraft engines) and associated components, equipment, and systems. It also includes research and development in aerodynamics, aeronautics, and ground support equipment for aeronautical vehicles.

10 CFR Appendix S to Part 50 - Earthquake Engineering Criteria for Nuclear Power Plants

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Earthquake Engineering Criteria for Nuclear Power Plants S... FACILITIES Pt. 50, App. S Appendix S to Part 50—Earthquake Engineering Criteria for Nuclear Power Plants... applicant or holder whose construction permit was issued before January 10, 1997, the earthquake engineering...

10 CFR Appendix S to Part 50 - Earthquake Engineering Criteria for Nuclear Power Plants

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 1 2013-01-01 2013-01-01 false Earthquake Engineering Criteria for Nuclear Power Plants S... FACILITIES Pt. 50, App. S Appendix S to Part 50—Earthquake Engineering Criteria for Nuclear Power Plants... applicant or holder whose construction permit was issued before January 10, 1997, the earthquake engineering...

10 CFR Appendix S to Part 50 - Earthquake Engineering Criteria for Nuclear Power Plants

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Earthquake Engineering Criteria for Nuclear Power Plants S... FACILITIES Pt. 50, App. S Appendix S to Part 50—Earthquake Engineering Criteria for Nuclear Power Plants... applicant or holder whose construction permit was issued before January 10, 1997, the earthquake engineering...

10 CFR Appendix S to Part 50 - Earthquake Engineering Criteria for Nuclear Power Plants

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 1 2014-01-01 2014-01-01 false Earthquake Engineering Criteria for Nuclear Power Plants S... FACILITIES Pt. 50, App. S Appendix S to Part 50—Earthquake Engineering Criteria for Nuclear Power Plants... applicant or holder whose construction permit was issued before January 10, 1997, the earthquake engineering...

Identifying Professional Competencies of the Flip-Chip Packaging Engineer in Taiwan

ERIC Educational Resources Information Center

Guu, Y. H.; Lin, Kuen-Yi; Lee, Lung-Sheng

2014-01-01

This study employed a literature review, expert interviews, and a questionnaire survey to construct a set of two-tier competencies for a flip-chip packaging engineer. The fuzzy Delphi questionnaire was sent to 12 flip-chip engineering experts to identify professional competencies that a flip-chip packaging engineer must have. Four competencies,…

Tissue-engineered cartilaginous constructs for the treatment of caprine cartilage defects, including distribution of laminin and type IV collagen.

PubMed

Jeng, Lily; Hsu, Hu-Ping; Spector, Myron

2013-10-01

The purpose of this study was the immunohistochemical evaluation of (1) cartilage tissue-engineered constructs; and (2) the tissue filling cartilage defects in a goat model into which the constructs were implanted, particularly for the presence of the basement membrane molecules, laminin and type IV collagen. Basement membrane molecules are localized to the pericellular matrix in normal adult articular cartilage, but have not been examined in tissue-engineered constructs cultured in vitro or in tissue filling cartilage defects into which the constructs were implanted. Cartilaginous constructs were engineered in vitro using caprine chondrocyte-seeded type II collagen scaffolds. Autologous constructs were implanted into 4-mm-diameter defects created to the tidemark in the trochlear groove in the knee joints of skeletally mature goats. Eight weeks after implantation, the animals were sacrificed. Constructs underwent immunohistochemical and histomorphometric evaluation. Widespread staining for the two basement membrane molecules was observed throughout the extracellular matrix of in vitro and in vivo samples in a distribution unlike that previously reported for cartilage. At sacrifice, 70% of the defect site was filled with reparative tissue, which consisted largely of fibrous tissue and some fibrocartilage, with over 70% of the reparative tissue bonded to the adjacent host tissue. A novel finding of this study was the observation of laminin and type IV collagen in in vitro engineered cartilaginous constructs and in vivo cartilage repair samples from defects into which the constructs were implanted, as well as in normal caprine articular cartilage. Future work is needed to elucidate the role of basement membrane molecules during cartilage repair and regeneration.

Tissue-Engineered Cartilaginous Constructs for the Treatment of Caprine Cartilage Defects, Including Distribution of Laminin and Type IV Collagen

PubMed Central

Jeng, Lily; Hsu, Hu-Ping

2013-01-01

The purpose of this study was the immunohistochemical evaluation of (1) cartilage tissue-engineered constructs; and (2) the tissue filling cartilage defects in a goat model into which the constructs were implanted, particularly for the presence of the basement membrane molecules, laminin and type IV collagen. Basement membrane molecules are localized to the pericellular matrix in normal adult articular cartilage, but have not been examined in tissue-engineered constructs cultured in vitro or in tissue filling cartilage defects into which the constructs were implanted. Cartilaginous constructs were engineered in vitro using caprine chondrocyte-seeded type II collagen scaffolds. Autologous constructs were implanted into 4-mm-diameter defects created to the tidemark in the trochlear groove in the knee joints of skeletally mature goats. Eight weeks after implantation, the animals were sacrificed. Constructs underwent immunohistochemical and histomorphometric evaluation. Widespread staining for the two basement membrane molecules was observed throughout the extracellular matrix of in vitro and in vivo samples in a distribution unlike that previously reported for cartilage. At sacrifice, 70% of the defect site was filled with reparative tissue, which consisted largely of fibrous tissue and some fibrocartilage, with over 70% of the reparative tissue bonded to the adjacent host tissue. A novel finding of this study was the observation of laminin and type IV collagen in in vitro engineered cartilaginous constructs and in vivo cartilage repair samples from defects into which the constructs were implanted, as well as in normal caprine articular cartilage. Future work is needed to elucidate the role of basement membrane molecules during cartilage repair and regeneration. PMID:23672504

An Exploratory Study of Students' Constructions of Gender in Science, Engineering and Technology

ERIC Educational Resources Information Center

Lynch, Ingrid; Nowosenetz, Tessa

2009-01-01

Despite an appreciation of the need to increase gender sensitivity and awareness among tertiary students in the field of science, engineering and technology (SET), there is a paucity of research that explores how students in this field construct gender. A greater understanding of such constructions can assist in transforming gender relations and…

Assessing Students' Sentiments towards the Use of a Building Information Modelling (BIM) Learning Platform in a Construction Project Management Course

ERIC Educational Resources Information Center

Suwal, Sunil; Singh, Vishal

2018-01-01

Building Information Modelling (BIM) tools and processes are increasingly adopted and implemented in the construction industry. Consequently, BIM education is considered increasingly important in Architecture, Engineering and Construction (AEC) education. While most of the research and literature on BIM education in engineering studies has focused…

An Analysis of Insulated Concrete Forms for use in Sustainable Military Construction

DTIC Science & Technology

2014-03-27

CONSTRUCTION THESIS Presented to the Faculty Department of Systems and Engineering Management Graduate School of Engineering and Management...which fit together and are filled with reinforced concrete to construct the exterior wall systems of a building. By design, this material provides a...Forms with Rebar .............................................................. 12 Figure 3. Cut outs of ICF wall systems

Identifying Indicators Related to Constructs for Engineering Design Outcome

ERIC Educational Resources Information Center

Wilhelmsen, Cheryl A.; Dixon, Raymond A.

2016-01-01

This study ranked constructs articulated by Childress and Rhodes (2008) and identified the key indicators for each construct as a starting point to explore what should be included on an instrument to measure the engineering design process and outcomes of students in high schools that use the PLTW and EbDTM curricula in Idaho. A case-study design…

Engineering design in the primary school: applying stem concepts to build an optical instrument

NASA Astrophysics Data System (ADS)

King, Donna; English, Lyn D.

2016-12-01

Internationally there is a need for research that focuses on STEM (Science, Technology, Engineering and Mathematics) education to equip students with the skills needed for a rapidly changing future. One way to do this is through designing engineering activities that reflect real-world problems and contextualise students' learning of STEM concepts. As such, this study examined the learning that occurred when fifth-grade students completed an optical engineering activity using an iterative engineering design model. Through a qualitative methodology using a case study design, we analysed multiple data sources including students' design sketches from eight focus groups. Three key findings emerged: first, the collaborative process of the first design sketch enabled students to apply core STEM concepts to model construction; second, during the construction stage students used experimentation for the positioning of lenses, mirrors and tubes resulting in a simpler 'working' model; and third, the redesign process enabled students to apply structural changes to their design. The engineering design model was useful for structuring stages of design, construction and redesign; however, we suggest a more flexible approach for advanced applications of STEM concepts in the future.

Wind Energy Workforce Development: Engineering, Science, & Technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lesieutre, George A.; Stewart, Susan W.; Bridgen, Marc

2013-03-29

Broadly, this project involved the development and delivery of a new curriculum in wind energy engineering at the Pennsylvania State University; this includes enhancement of the Renewable Energy program at the Pennsylvania College of Technology. The new curricula at Penn State includes addition of wind energy-focused material in more than five existing courses in aerospace engineering, mechanical engineering, engineering science and mechanics and energy engineering, as well as three new online graduate courses. The online graduate courses represent a stand-alone Graduate Certificate in Wind Energy, and provide the core of a Wind Energy Option in an online intercollege professional Mastersmore » degree in Renewable Energy and Sustainability Systems. The Pennsylvania College of Technology erected a 10 kilowatt Xzeres wind turbine that is dedicated to educating the renewable energy workforce. The entire construction process was incorporated into the Renewable Energy A.A.S. degree program, the Building Science and Sustainable Design B.S. program, and other construction-related coursework throughout the School of Construction and Design Technologies. Follow-on outcomes include additional non-credit opportunities as well as secondary school career readiness events, community outreach activities, and public awareness postings.« less

Challenges in engineering osteochondral tissue grafts with hierarchical structures.

PubMed

Gadjanski, Ivana; Vunjak-Novakovic, Gordana

2015-01-01

A major hurdle in treating osteochondral (OC) defects is the different healing abilities of two types of tissues involved - articular cartilage and subchondral bone. Biomimetic approaches to OC-construct engineering, based on recapitulation of biological principles of tissue development and regeneration, have potential for providing new treatments and advancing fundamental studies of OC tissue repair. This review on state of the art in hierarchical OC tissue graft engineering is focused on tissue engineering approaches designed to recapitulate the native milieu of cartilage and bone development. These biomimetic systems are discussed with relevance to bioreactor cultivation of clinically sized, anatomically shaped human cartilage/bone constructs with physiologic stratification and mechanical properties. The utility of engineered OC tissue constructs is evaluated for their use as grafts in regenerative medicine, and as high-fidelity models in biological research. A major challenge in engineering OC tissues is to generate a functionally integrated stratified cartilage-bone structure starting from one single population of mesenchymal cells, while incorporating perfusable vasculature into the bone, and in bone-cartilage interface. To this end, new generations of advanced scaffolds and bioreactors, implementation of mechanical loading regimens and harnessing of inflammatory responses of the host will likely drive the further progress.

Army Corps of Engineers: Better Guidance Could Improve Corps’ Information on Water Resources Projects Undertaken by Nonfederal Sponsors

DTIC Science & Technology

2016-12-01

Nonfederal Sponsors Why GAO Did This Study Through its Civil Works program, the Corps designs , constructs, and maintains federal water resources...Public Works United States Senate Dear Mr. Chairman: The U.S. Army Corps of Engineers (Corps) is the world’s largest public engineering, design ...its Civil Works Program, in general, the Corps plans, designs , constructs, operates, and maintains a wide range of water resources projects. Congress