Sample records for enhance spatial resolution

  1. Enhancing Spatial Resolution of Remotely Sensed Imagery Using Deep Learning

    NASA Astrophysics Data System (ADS)

    Beck, J. M.; Bridges, S.; Collins, C.; Rushing, J.; Graves, S. J.

    2017-12-01

    Researchers at the Information Technology and Systems Center at the University of Alabama in Huntsville are using Deep Learning with Convolutional Neural Networks (CNNs) to develop a method for enhancing the spatial resolutions of moderate resolution (10-60m) multispectral satellite imagery. This enhancement will effectively match the resolutions of imagery from multiple sensors to provide increased global temporal-spatial coverage for a variety of Earth science products. Our research is centered on using Deep Learning for automatically generating transformations for increasing the spatial resolution of remotely sensed images with different spatial, spectral, and temporal resolutions. One of the most important steps in using images from multiple sensors is to transform the different image layers into the same spatial resolution, preferably the highest spatial resolution, without compromising the spectral information. Recent advances in Deep Learning have shown that CNNs can be used to effectively and efficiently upscale or enhance the spatial resolution of multispectral images with the use of an auxiliary data source such as a high spatial resolution panchromatic image. In contrast, we are using both the spatial and spectral details inherent in low spatial resolution multispectral images for image enhancement without the use of a panchromatic image. This presentation will discuss how this technology will benefit many Earth Science applications that use remotely sensed images with moderate spatial resolutions.

  2. Emotional cues enhance the attentional effects on spatial and temporal resolution.

    PubMed

    Bocanegra, Bruno R; Zeelenberg, René

    2011-12-01

    In the present study, we demonstrated that the emotional significance of a spatial cue enhances the effect of covert attention on spatial and temporal resolution (i.e., our ability to discriminate small spatial details and fast temporal flicker). Our results indicated that fearful face cues, as compared with neutral face cues, enhanced the attentional benefits in spatial resolution but also enhanced the attentional deficits in temporal resolution. Furthermore, we observed that the overall magnitudes of individuals' attentional effects correlated strongly with the magnitude of the emotion × attention interaction effect. Combined, these findings provide strong support for the idea that emotion enhances the strength of a cue's attentional response.

  3. Effect of Electric Field Gradient on Sub-nanometer Spatial Resolution of Tip-enhanced Raman Spectroscopy

    PubMed Central

    Meng, Lingyan; Yang, Zhilin; Chen, Jianing; Sun, Mengtao

    2015-01-01

    Tip-enhanced Raman spectroscopy (TERS) with sub-nanometer spatial resolution has been recently demonstrated experimentally. However, the physical mechanism underlying is still under discussion. Here we theoretically investigate the electric field gradient of a coupled tip-substrate system. Our calculations suggest that the ultra-high spatial resolution of TERS can be partially attributed to the electric field gradient effect owning to its tighter spatial confinement and sensitivity to the infrared (IR)-active of molecules. Particularly, in the case of TERS of flat-lying H2TBPP molecules,we find the electric field gradient enhancement is the dominating factor for the high spatial resolution, which qualitatively coincides with previous experimental report. Our theoretical study offers a new paradigm for understanding the mechanisms of the ultra-high spatial resolution demonstrated in tip-enhanced spectroscopy which is of importance but neglected. PMID:25784161

  4. The effects of transient attention on spatial resolution and the size of the attentional cue.

    PubMed

    Yeshurun, Yaffa; Carrasco, Marisa

    2008-01-01

    It has been shown that transient attention enhances spatial resolution, but is the effect of transient attention on spatial resolution modulated by the size of the attentional cue? Would a gradual increase in the size of the cue lead to a gradual decrement in spatial resolution? To test these hypotheses, we used a texture segmentation task in which performance depends on spatial resolution, and systematically manipulated the size of the attentional cue: A bar of different lengths (Experiment 1) or a frame of different sizes (Experiments 2-3) indicated the target region in a texture segmentation display. Observers indicated whether a target patch region (oriented line elements in a background of an orthogonal orientation), appearing at a range of eccentricities, was present in the first or the second interval. We replicated the attentional enhancement of spatial resolution found with small cues; attention improved performance at peripheral locations but impaired performance at central locations. However, there was no evidence of gradual resolution decrement with large cues. Transient attention enhanced spatial resolution at the attended location when it was attracted to that location by a small cue but did not affect resolution when it was attracted by a large cue. These results indicate that transient attention cannot adapt its operation on spatial resolution on the basis of the size of the attentional cue.

  5. Selective spatial enhancement: Attentional spotlight size impacts spatial but not temporal perception.

    PubMed

    Goodhew, Stephanie C; Shen, Elizabeth; Edwards, Mark

    2016-08-01

    An important but often neglected aspect of attention is how changes in the attentional spotlight size impact perception. The zoom-lens model predicts that a small ("focal") attentional spotlight enhances all aspects of perception relative to a larger ("diffuse" spotlight). However, based on the physiological properties of the two major classes of visual cells (magnocellular and parvocellular neurons) we predicted trade-offs in spatial and temporal acuity as a function of spotlight size. Contrary to both of these accounts, however, across two experiments we found that attentional spotlight size affected spatial acuity, such that spatial acuity was enhanced for a focal relative to a diffuse spotlight, whereas the same modulations in spotlight size had no impact on temporal acuity. This likely reflects the function of attention: to induce the high spatial resolution of the fovea in periphery, where spatial resolution is poor but temporal resolution is good. It is adaptive, therefore, for the attentional spotlight to enhance spatial acuity, whereas enhancing temporal acuity does not confer the same benefit.

  6. Spatial and Angular Resolution Enhancement of Light Fields Using Convolutional Neural Networks

    NASA Astrophysics Data System (ADS)

    Gul, M. Shahzeb Khan; Gunturk, Bahadir K.

    2018-05-01

    Light field imaging extends the traditional photography by capturing both spatial and angular distribution of light, which enables new capabilities, including post-capture refocusing, post-capture aperture control, and depth estimation from a single shot. Micro-lens array (MLA) based light field cameras offer a cost-effective approach to capture light field. A major drawback of MLA based light field cameras is low spatial resolution, which is due to the fact that a single image sensor is shared to capture both spatial and angular information. In this paper, we present a learning based light field enhancement approach. Both spatial and angular resolution of captured light field is enhanced using convolutional neural networks. The proposed method is tested with real light field data captured with a Lytro light field camera, clearly demonstrating spatial and angular resolution improvement.

  7. Spatial and Angular Resolution Enhancement of Light Fields Using Convolutional Neural Networks.

    PubMed

    Gul, M Shahzeb Khan; Gunturk, Bahadir K

    2018-05-01

    Light field imaging extends the traditional photography by capturing both spatial and angular distribution of light, which enables new capabilities, including post-capture refocusing, post-capture aperture control, and depth estimation from a single shot. Micro-lens array (MLA) based light field cameras offer a cost-effective approach to capture light field. A major drawback of MLA based light field cameras is low spatial resolution, which is due to the fact that a single image sensor is shared to capture both spatial and angular information. In this paper, we present a learning based light field enhancement approach. Both spatial and angular resolution of captured light field is enhanced using convolutional neural networks. The proposed method is tested with real light field data captured with a Lytro light field camera, clearly demonstrating spatial and angular resolution improvement.

  8. Zonal wavefront sensing with enhanced spatial resolution.

    PubMed

    Pathak, Biswajit; Boruah, Bosanta R

    2016-12-01

    In this Letter, we introduce a scheme to enhance the spatial resolution of a zonal wavefront sensor. The zonal wavefront sensor comprises an array of binary gratings implemented by a ferroelectric spatial light modulator (FLCSLM) followed by a lens, in lieu of the array of lenses in the Shack-Hartmann wavefront sensor. We show that the fast response of the FLCSLM device facilitates quick display of several laterally shifted binary grating patterns, and the programmability of the device enables simultaneous capturing of each focal spot array. This eventually leads to a wavefront estimation with an enhanced spatial resolution without much sacrifice on the sensor frame rate, thus making the scheme suitable for high spatial resolution measurement of transient wavefronts. We present experimental and numerical simulation results to demonstrate the importance of the proposed wavefront sensing scheme.

  9. A technique for enhancing and matching the resolution of microwave measurements from the SSM/I instrument

    NASA Technical Reports Server (NTRS)

    Robinson, Wayne D.; Kummerrow, Christian; Olson, William S.

    1992-01-01

    A correction technique is presented for matching the resolution of all the frequencies of the satelliteborne Special Sensor Microwave/Imager (SSM/I) to the about-25-km spatial resolution of the 37-GHz channel. This entails, on the one hand, the enhancement of the spatial resolution of the 19- and 22-GHz channels, and on the other, the degrading of that of the 85-GHz channel. The Backus and Gilbert (1970) approach is found to yield sufficient spatial resolution to render such a correction worthwhile.

  10. Resolution Enhancement of Hyperion Hyperspectral Data using Ikonos Multispectral Data

    DTIC Science & Technology

    2007-09-01

    spatial - resolution hyperspectral image to produce a sharpened product. The result is a product that has the spectral properties of the ...multispectral sensors. In this work, we examine the benefits of combining data from high- spatial - resolution , low- spectral - resolution spectral imaging...sensors with data obtained from high- spectral - resolution , low- spatial - resolution spectral imaging sensors.

  11. The Effect of Remote Sensor Spatial Resolution in Monitoring U.S. Army Training Maneuver Sites

    DTIC Science & Technology

    1990-12-01

    THE EFFECT OF REMOTE SENSOR SPATIAL RESOLUTION IN MONITORING U.S. ARMY...Multispectral Scanner with 6.5 meter spatial resolution provided the most effective digital data set for enhancing tank trails. However, this Airborne Scanner...primary objective of this research was to determine the capabilities and limitations of remote sensor systems having different spatial resolutions to

  12. Enhancing resolution and contrast in second-harmonic generation microscopy using an advanced maximum likelihood estimation restoration method

    NASA Astrophysics Data System (ADS)

    Sivaguru, Mayandi; Kabir, Mohammad M.; Gartia, Manas Ranjan; Biggs, David S. C.; Sivaguru, Barghav S.; Sivaguru, Vignesh A.; Berent, Zachary T.; Wagoner Johnson, Amy J.; Fried, Glenn A.; Liu, Gang Logan; Sadayappan, Sakthivel; Toussaint, Kimani C.

    2017-02-01

    Second-harmonic generation (SHG) microscopy is a label-free imaging technique to study collagenous materials in extracellular matrix environment with high resolution and contrast. However, like many other microscopy techniques, the actual spatial resolution achievable by SHG microscopy is reduced by out-of-focus blur and optical aberrations that degrade particularly the amplitude of the detectable higher spatial frequencies. Being a two-photon scattering process, it is challenging to define a point spread function (PSF) for the SHG imaging modality. As a result, in comparison with other two-photon imaging systems like two-photon fluorescence, it is difficult to apply any PSF-engineering techniques to enhance the experimental spatial resolution closer to the diffraction limit. Here, we present a method to improve the spatial resolution in SHG microscopy using an advanced maximum likelihood estimation (AdvMLE) algorithm to recover the otherwise degraded higher spatial frequencies in an SHG image. Through adaptation and iteration, the AdvMLE algorithm calculates an improved PSF for an SHG image and enhances the spatial resolution by decreasing the full-width-at-halfmaximum (FWHM) by 20%. Similar results are consistently observed for biological tissues with varying SHG sources, such as gold nanoparticles and collagen in porcine feet tendons. By obtaining an experimental transverse spatial resolution of 400 nm, we show that the AdvMLE algorithm brings the practical spatial resolution closer to the theoretical diffraction limit. Our approach is suitable for adaptation in micro-nano CT and MRI imaging, which has the potential to impact diagnosis and treatment of human diseases.

  13. Spatially enhanced passive microwave derived soil moisture: capabilities and opportunities

    USDA-ARS?s Scientific Manuscript database

    Low frequency passive microwave remote sensing is a proven technique for soil moisture retrieval, but its coarse resolution restricts the range of applications. Downscaling, otherwise known as disaggregation, has been proposed as the solution to spatially enhance these coarse resolution soil moistur...

  14. Attentional enhancement of spatial resolution: linking behavioural and neurophysiological evidence

    PubMed Central

    Anton-Erxleben, Katharina; Carrasco, Marisa

    2014-01-01

    Attention allows us to select relevant sensory information for preferential processing. Behaviourally, it improves performance in various visual tasks. One prominent effect of attention is the modulation of performance in tasks that involve the visual system’s spatial resolution. Physiologically, attention modulates neuronal responses and alters the profile and position of receptive fields near the attended location. Here, we develop a hypothesis linking the behavioural and electrophysiological evidence. The proposed framework seeks to explain how these receptive field changes enhance the visual system’s effective spatial resolution and how the same mechanisms may also underlie attentional effects on the representation of spatial information. PMID:23422910

  15. Resolution-enhanced Mapping Spectrometer

    NASA Technical Reports Server (NTRS)

    Kumer, J. B.; Aubrun, J. N.; Rosenberg, W. J.; Roche, A. E.

    1993-01-01

    A familiar mapping spectrometer implementation utilizes two dimensional detector arrays with spectral dispersion along one direction and spatial along the other. Spectral images are formed by spatially scanning across the scene (i.e., push-broom scanning). For imaging grating and prism spectrometers, the slit is perpendicular to the spatial scan direction. For spectrometers utilizing linearly variable focal-plane-mounted filters the spatial scan direction is perpendicular to the direction of spectral variation. These spectrometers share the common limitation that the number of spectral resolution elements is given by the number of pixels along the spectral (or dispersive) direction. Resolution enhancement by first passing the light input to the spectrometer through a scanned etalon or Michelson is discussed. Thus, while a detector element is scanned through a spatial resolution element of the scene, it is also temporally sampled. The analysis for all the pixels in the dispersive direction is addressed. Several specific examples are discussed. The alternate use of a Michelson for the same enhancement purpose is also discussed. Suitable for weight constrained deep space missions, hardware systems were developed including actuators, sensor, and electronics such that low-resolution etalons with performance required for implementation would weigh less than one pound.

  16. Spatial resolution enhancement of terrestrial features using deconvolved SSM/I microwave brightness temperatures

    NASA Technical Reports Server (NTRS)

    Farrar, Michael R.; Smith, Eric A.

    1992-01-01

    A method for enhancing the 19, 22, and 37 GHz measurements of the SSM/I (Special Sensor Microwave/Imager) to the spatial resolution and sampling density of the high resolution 85-GHz channel is presented. An objective technique for specifying the tuning parameter, which balances the tradeoff between resolution and noise, is developed in terms of maximizing cross-channel correlations. Various validation procedures are performed to demonstrate the effectiveness of the method, which hopefully will provide researchers with a valuable tool in multispectral applications of satellite radiometer data.

  17. Signal enhancement and Patterson-search phasing for high-spatial-resolution coherent X-ray diffraction imaging of biological objects.

    PubMed

    Takayama, Yuki; Maki-Yonekura, Saori; Oroguchi, Tomotaka; Nakasako, Masayoshi; Yonekura, Koji

    2015-01-28

    In this decade coherent X-ray diffraction imaging has been demonstrated to reveal internal structures of whole biological cells and organelles. However, the spatial resolution is limited to several tens of nanometers due to the poor scattering power of biological samples. The challenge is to recover correct phase information from experimental diffraction patterns that have a low signal-to-noise ratio and unmeasurable lowest-resolution data. Here, we propose a method to extend spatial resolution by enhancing diffraction signals and by robust phasing. The weak diffraction signals from biological objects are enhanced by interference with strong waves from dispersed colloidal gold particles. The positions of the gold particles determined by Patterson analysis serve as the initial phase, and this dramatically improves reliability and convergence of image reconstruction by iterative phase retrieval. A set of calculations based on current experiments demonstrates that resolution is improved by a factor of two or more.

  18. Signal enhancement and Patterson-search phasing for high-spatial-resolution coherent X-ray diffraction imaging of biological objects

    PubMed Central

    Takayama, Yuki; Maki-Yonekura, Saori; Oroguchi, Tomotaka; Nakasako, Masayoshi; Yonekura, Koji

    2015-01-01

    In this decade coherent X-ray diffraction imaging has been demonstrated to reveal internal structures of whole biological cells and organelles. However, the spatial resolution is limited to several tens of nanometers due to the poor scattering power of biological samples. The challenge is to recover correct phase information from experimental diffraction patterns that have a low signal-to-noise ratio and unmeasurable lowest-resolution data. Here, we propose a method to extend spatial resolution by enhancing diffraction signals and by robust phasing. The weak diffraction signals from biological objects are enhanced by interference with strong waves from dispersed colloidal gold particles. The positions of the gold particles determined by Patterson analysis serve as the initial phase, and this dramatically improves reliability and convergence of image reconstruction by iterative phase retrieval. A set of calculations based on current experiments demonstrates that resolution is improved by a factor of two or more. PMID:25627480

  19. Super resolution PLIF demonstrated in turbulent jet flows seeded with I2

    NASA Astrophysics Data System (ADS)

    Xu, Wenjiang; Liu, Ning; Ma, Lin

    2018-05-01

    Planar laser induced fluorescence (PLIF) represents an indispensable tool for flow and flame imaging. However, the PLIF technique suffers from limited spatial resolution or blurring in many situations, which restricts its applicability and capability. This work describes a new method, named SR-PLIF (super-resolution PLIF), to overcome these limitations and enhance the capability of PLIF. The method uses PLIF images captured simultaneously from two (or more) orientations to reconstruct a final PLIF image with resolution enhanced or blurring removed. This paper reports the development of the reconstruction algorithm, and the experimental demonstration of the SR-PLIF method both with controlled samples and with turbulent flows seeded with iodine vapor. Using controlled samples with two cameras, the spatial resolution in the best case was improved from 0.06 mm in the projections to 0.03 mm in the SR image, in terms of the spreading width of a sharp edge. With turbulent flows, an image sharpness measure was developed to quantify the spatial resolution, and SR reconstruction with two cameras can effectively improve the spatial resolution compared to the projections in terms of the sharpness measure.

  20. High spatial resolution distributed optical fiber dynamic strain sensor with enhanced frequency and strain resolution.

    PubMed

    Masoudi, Ali; Newson, Trevor P

    2017-01-15

    A distributed optical fiber dynamic strain sensor with high spatial and frequency resolution is demonstrated. The sensor, which uses the ϕ-OTDR interrogation technique, exhibited a higher sensitivity thanks to an improved optical arrangement and a new signal processing procedure. The proposed sensing system is capable of fully quantifying multiple dynamic perturbations along a 5 km long sensing fiber with a frequency and spatial resolution of 5 Hz and 50 cm, respectively. The strain resolution of the sensor was measured to be 40 nε.

  1. Super-Resolution Reconstruction of Remote Sensing Images Using Multifractal Analysis

    PubMed Central

    Hu, Mao-Gui; Wang, Jin-Feng; Ge, Yong

    2009-01-01

    Satellite remote sensing (RS) is an important contributor to Earth observation, providing various kinds of imagery every day, but low spatial resolution remains a critical bottleneck in a lot of applications, restricting higher spatial resolution analysis (e.g., intra-urban). In this study, a multifractal-based super-resolution reconstruction method is proposed to alleviate this problem. The multifractal characteristic is common in Nature. The self-similarity or self-affinity presented in the image is useful to estimate details at larger and smaller scales than the original. We first look for the presence of multifractal characteristics in the images. Then we estimate parameters of the information transfer function and noise of the low resolution image. Finally, a noise-free, spatial resolution-enhanced image is generated by a fractal coding-based denoising and downscaling method. The empirical case shows that the reconstructed super-resolution image performs well in detail enhancement. This method is not only useful for remote sensing in investigating Earth, but also for other images with multifractal characteristics. PMID:22291530

  2. Working memory-driven attention improves spatial resolution: Support for perceptual enhancement.

    PubMed

    Pan, Yi; Luo, Qianying; Cheng, Min

    2016-08-01

    Previous research has indicated that attention can be biased toward those stimuli matching the contents of working memory and thereby facilitates visual processing at the location of the memory-matching stimuli. However, whether this working memory-driven attentional modulation takes place on early perceptual processes remains unclear. Our present results showed that working memory-driven attention improved identification of a brief Landolt target presented alone in the visual field. Because the suprathreshold target appeared without any external noise added (i.e., no distractors or masks), the results suggest that working memory-driven attention enhances the target signal at early perceptual stages of visual processing. Furthermore, given that performance in the Landolt target identification task indexes spatial resolution, this attentional facilitation indicates that working memory-driven attention can boost early perceptual processing via enhancement of spatial resolution at the attended location.

  3. Stretchable Dry Electrodes with Concentric Ring Geometry for Enhancing Spatial Resolution in Electrophysiology.

    PubMed

    Wang, Kaiping; Parekh, Udit; Pailla, Tejaswy; Garudadri, Harinath; Gilja, Vikash; Ng, Tse Nga

    2017-10-01

    The multichannel concentric-ring electrodes are stencil printed on stretchable elastomers modified to improve adhesion to skin and minimize motion artifacts for electrophysiological recordings of electroencephalography, electromyography, and electrocardiography. These dry electrodes with a poly(3,4-ethylenedioxythiophene) polystyrene sulfonate interface layer are optimized to show lower noise level than that of commercial gel disc electrodes. The concentric ring geometry enables Laplacian filtering to pinpoint the bioelectric potential source with spatial resolution determined by the ring distance. This work shows a new fabrication approach to integrate and create designs that enhance spatial resolution for high-quality electrophysiology monitoring devices. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Implementation of spatial overlap modulation nonlinear optical microscopy using an electro-optic deflector

    PubMed Central

    Isobe, Keisuke; Kawano, Hiroyuki; Kumagai, Akiko; Miyawaki, Atsushi; Midorikawa, Katsumi

    2013-01-01

    A spatial overlap modulation (SPOM) technique is a nonlinear optical microscopy technique which enhances the three-dimensional spatial resolution and rejects the out-of-focus background limiting the imaging depth inside a highly scattering sample. Here, we report on the implementation of SPOM in which beam pointing modulation is achieved by an electro-optic deflector. The modulation and demodulation frequencies are enhanced to 200 kHz and 400 kHz, respectively, resulting in a 200-fold enhancement compared with the previously reported system. The resolution enhancement and suppression of the out-of-focus background are demonstrated by sum-frequency-generation imaging of pounded granulated sugar and deep imaging of fluorescent beads in a tissue-like phantom, respectively. PMID:24156055

  5. Tip-enhanced near-field Raman spectroscopy with a scanning tunneling microscope and side-illumination optics.

    PubMed

    Yi, K J; He, X N; Zhou, Y S; Xiong, W; Lu, Y F

    2008-07-01

    Conventional Raman spectroscopy (RS) suffers from low spatial resolution and low detection sensitivity due to the optical diffraction limit and small interaction cross sections. It has been reported that a highly localized and significantly enhanced electromagnetic field could be generated in the proximity of a metallic tip illuminated by a laser beam. In this study, a tip-enhanced RS system was developed to both improve the resolution and enhance the detection sensitivity using the tip-enhanced near-field effects. This instrument, by combining RS with a scanning tunneling microscope and side-illumination optics, demonstrated significant enhancement on both optical sensitivity and spatial resolution using either silver (Ag)-coated tungsten (W) tips or gold (Au) tips. The sensitivity improvement was verified by observing the enhancement effects on silicon (Si) substrates. Lateral resolution was verified to be below 100 nm by mapping Ag nanostructures. By deploying the depolarization technique, an apparent enhancement of 175% on Si substrates was achieved. Furthermore, the developed instrument features fast and reliable optical alignment, versatile sample adaptability, and effective suppression of far-field signals.

  6. Effects of satellite image spatial aggregation and resolution on estimates of forest land area

    Treesearch

    M.D. Nelson; R.E. McRoberts; G.R. Holden; M.E. Bauer

    2009-01-01

    Satellite imagery is being used increasingly in association with national forest inventories (NFIs) to produce maps and enhance estimates of forest attributes. We simulated several image spatial resolutions within sparsely and heavily forested study areas to assess resolution effects on estimates of forest land area, independent of other sensor characteristics. We...

  7. Terahertz Near-Field Imaging Using Enhanced Transmission through a Single Subwavelength Aperture

    NASA Astrophysics Data System (ADS)

    Ishihara, Kunihiko; Ikari, Tomofumi; Minamide, Hiroaki; Shikata, Jun-ichi; Ohashi, Keishi; Yokoyama, Hiroyuki; Ito, Hiromasa

    2005-07-01

    We demonstrate terahertz (THz) near-field imaging using resonantly enhanced transmission of THz-wave radiation (λ˜ 200 μm) through a bull’s eye structure (a single subwavelength aperture surrounded by concentric periodic grooves in a metal plate). The bull’s eye structure shows extremely large enhanced transmission, which has the advantage for a single subwavelength aperture. The spatial resolution for the bull’s eye structure (with an aperture diameter d=100 μm) is evaluated in the near-field region, and a resolution of 50 μm (corresponding to λ/4) is achieved. We obtain the THz near-field images of the subwavelength metal pattern with a spatial resolution below the diffraction limit.

  8. Sub-pixel mapping of hyperspectral imagery using super-resolution

    NASA Astrophysics Data System (ADS)

    Sharma, Shreya; Sharma, Shakti; Buddhiraju, Krishna M.

    2016-04-01

    With the development of remote sensing technologies, it has become possible to obtain an overview of landscape elements which helps in studying the changes on earth's surface due to climate, geological, geomorphological and human activities. Remote sensing measures the electromagnetic radiations from the earth's surface and match the spectral similarity between the observed signature and the known standard signatures of the various targets. However, problem lies when image classification techniques assume pixels to be pure. In hyperspectral imagery, images have high spectral resolution but poor spatial resolution. Therefore, the spectra obtained is often contaminated due to the presence of mixed pixels and causes misclassification. To utilise this high spectral information, spatial resolution has to be enhanced. Many factors make the spatial resolution one of the most expensive and hardest to improve in imaging systems. To solve this problem, post-processing of hyperspectral images is done to retrieve more information from the already acquired images. The algorithm to enhance spatial resolution of the images by dividing them into sub-pixels is known as super-resolution and several researches have been done in this domain.In this paper, we propose a new method for super-resolution based on ant colony optimization and review the popular methods of sub-pixel mapping of hyperspectral images along with their comparative analysis.

  9. Long-distance super-resolution imaging assisted by enhanced spatial Fourier transform.

    PubMed

    Tang, Heng-He; Liu, Pu-Kun

    2015-09-07

    A new gradient-index (GRIN) lens that can realize enhanced spatial Fourier transform (FT) over optically long distances is demonstrated. By using an anisotropic GRIN metamaterial with hyperbolic dispersion, evanescent wave in free space can be transformed into propagating wave in the metamaterial and then focused outside due to negative-refraction. Both the results based on the ray tracing and the finite element simulation show that the spatial frequency bandwidth of the spatial FT can be extended to 2.7k(0) (k(0) is the wave vector in free space). Furthermore, assisted by the enhanced spatial FT, a new long-distance (in the optical far-field region) super-resolution imaging scheme is also proposed and the super resolved capability of λ/5 (λ is the wavelength in free space) is verified. The work may provide technical support for designing new-type high-speed microscopes with long working distances.

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ogura, Toshihiko, E-mail: t-ogura@aist.go.jp

    Highlights: • We developed a high-sensitive frequency transmission electric-field (FTE) system. • The output signal was highly enhanced by applying voltage to a metal layer on SiN. • The spatial resolution of new FTE method is 41 nm. • New FTE system enables observation of the intact bacteria and virus in water. - Abstract: The high-resolution structural analysis of biological specimens by scanning electron microscopy (SEM) presents several advantages. Until now, wet bacterial specimens have been examined using atmospheric sample holders. However, images of unstained specimens in water using these holders exhibit very poor contrast and heavy radiation damage. Recently,more » we developed the frequency transmission electric-field (FTE) method, which facilitates the SEM observation of biological specimens in water without radiation damage. However, the signal detection system presents low sensitivity. Therefore, a high EB current is required to generate clear images, and thus reducing spatial resolution and inducing thermal damage to the samples. Here a high-sensitivity detection system is developed for the FTE method, which enhances the output signal amplitude by hundredfold. The detection signal was highly enhanced when voltage was applied to the metal layer on silicon nitride thin film. This enhancement reduced the EB current and improved the spatial resolution as well as the signal-to-noise ratio. The spatial resolution of a high-sensitive FTE system is 41 nm, which is considerably higher than previous FTE system. New FTE system can easily be utilised to examine various unstained biological specimens in water, such as living bacteria and viruses.« less

  11. Terahertz-wave near-field imaging with subwavelength resolution using surface-wave-assisted bow-tie aperture

    NASA Astrophysics Data System (ADS)

    Ishihara, Kunihiko; Ohashi, Keishi; Ikari, Tomofumi; Minamide, Hiroaki; Yokoyama, Hiroyuki; Shikata, Jun-ichi; Ito, Hiromasa

    2006-11-01

    We demonstrate the terahertz-wave near-field imaging with subwavelength resolution using a bow-tie shaped aperture surrounded by concentric periodic structures in a metal film. A subwavelength aperture with concentric periodic grooves, which are known as a bull's eye structure, shows extremely large enhanced transmission beyond the diffraction limit caused by the resonant excitation of surface waves. Additionally, a bow-tie aperture exhibits extraordinary field enhancement at the sharp tips of the metal, which enhances the transmission and the subwavelength spatial resolution. We introduced a bow-tie aperture to the bull's eye structure and achieved high spatial resolution (˜λ/17) in the near-field region. The terahertz-wave near-field image of the subwavelength metal pattern (pattern width=20μm) was obtained for the wavelength of 207μm.

  12. Spatial light modulator array with heat minimization and image enhancement features

    DOEpatents

    Jain, Kanti [Briarcliff Manor, NY; Sweatt, William C [Albuquerque, NM; Zemel, Marc [New Rochelle, NY

    2007-01-30

    An enhanced spatial light modulator (ESLM) array, a microelectronics patterning system and a projection display system using such an ESLM for heat-minimization and resolution enhancement during imaging, and the method for fabricating such an ESLM array. The ESLM array includes, in each individual pixel element, a small pixel mirror (reflective region) and a much larger pixel surround. Each pixel surround includes diffraction-grating regions and resolution-enhancement regions. During imaging, a selected pixel mirror reflects a selected-pixel beamlet into the capture angle of a projection lens, while the diffraction grating of the pixel surround redirects heat-producing unused radiation away from the projection lens. The resolution-enhancement regions of selected pixels provide phase shifts that increase effective modulation-transfer function in imaging. All of the non-selected pixel surrounds redirect all radiation energy away from the projection lens. All elements of the ESLM are fabricated by deposition, patterning, etching and other microelectronic process technologies.

  13. Estimation of Orbital Neutron Detector Spatial Resolution by Systematic Shifting of Differential Topographic Masks

    NASA Technical Reports Server (NTRS)

    McClanahan, T. P.; Mitrofanov, I. G.; Boynton, W. V.; Chin, G.; Livengood, T.; Starr, R. D.; Evans, L. G.; Mazarico, E.; Smith, D. E.

    2012-01-01

    We present a method and preliminary results related to determining the spatial resolution of orbital neutron detectors using epithermal maps and differential topographic masks. Our technique is similar to coded aperture imaging methods for optimizing photonic signals in telescopes [I]. In that approach photon masks with known spatial patterns in a telescope aperature are used to systematically restrict incoming photons which minimizes interference and enhances photon signal to noise. Three orbital neutron detector systems with different stated spatial resolutions are evaluated. The differing spatial resolutions arise due different orbital altitudes and the use of neutron collimation techniques. 1) The uncollimated Lunar Prospector Neutron Spectrometer (LPNS) system has spatial resolution of 45km FWHM from approx. 30km altitude mission phase [2]. The Lunar Rennaissance Orbiter (LRO) Lunar Exploration Neutron Detector (LEND) with two detectors at 50km altitude evaluated here: 2) the collimated 10km FWHM spatial resolution detector CSETN and 3) LEND's collimated Sensor for Epithermal Neutrons (SETN). Thus providing two orbital altitudes to study factors of: uncollimated vs collimated and two average altitudes for their effect on fields-of-view.

  14. Employing temporal self-similarity across the entire time domain in computed tomography reconstruction

    PubMed Central

    Kazantsev, D.; Van Eyndhoven, G.; Lionheart, W. R. B.; Withers, P. J.; Dobson, K. J.; McDonald, S. A.; Atwood, R.; Lee, P. D.

    2015-01-01

    There are many cases where one needs to limit the X-ray dose, or the number of projections, or both, for high frame rate (fast) imaging. Normally, it improves temporal resolution but reduces the spatial resolution of the reconstructed data. Fortunately, the redundancy of information in the temporal domain can be employed to improve spatial resolution. In this paper, we propose a novel regularizer for iterative reconstruction of time-lapse computed tomography. The non-local penalty term is driven by the available prior information and employs all available temporal data to improve the spatial resolution of each individual time frame. A high-resolution prior image from the same or a different imaging modality is used to enhance edges which remain stationary throughout the acquisition time while dynamic features tend to be regularized spatially. Effective computational performance together with robust improvement in spatial and temporal resolution makes the proposed method a competitive tool to state-of-the-art techniques. PMID:25939621

  15. Multispectral image enhancement processing for microsat-borne imager

    NASA Astrophysics Data System (ADS)

    Sun, Jianying; Tan, Zheng; Lv, Qunbo; Pei, Linlin

    2017-10-01

    With the rapid development of remote sensing imaging technology, the micro satellite, one kind of tiny spacecraft, appears during the past few years. A good many studies contribute to dwarfing satellites for imaging purpose. Generally speaking, micro satellites weigh less than 100 kilograms, even less than 50 kilograms, which are slightly larger or smaller than the common miniature refrigerators. However, the optical system design is hard to be perfect due to the satellite room and weight limitation. In most cases, the unprocessed data captured by the imager on the microsatellite cannot meet the application need. Spatial resolution is the key problem. As for remote sensing applications, the higher spatial resolution of images we gain, the wider fields we can apply them. Consequently, how to utilize super resolution (SR) and image fusion to enhance the quality of imagery deserves studying. Our team, the Key Laboratory of Computational Optical Imaging Technology, Academy Opto-Electronics, is devoted to designing high-performance microsat-borne imagers and high-efficiency image processing algorithms. This paper addresses a multispectral image enhancement framework for space-borne imagery, jointing the pan-sharpening and super resolution techniques to deal with the spatial resolution shortcoming of microsatellites. We test the remote sensing images acquired by CX6-02 satellite and give the SR performance. The experiments illustrate the proposed approach provides high-quality images.

  16. Swept Field Laser Confocal Microscopy for Enhanced Spatial and Temporal Resolution in Live-Cell Imaging

    PubMed Central

    Castellano-Muñoz, Manuel; Peng, Anthony Wei; Salles, Felipe T.; Ricci, Anthony J.

    2013-01-01

    Confocal fluorescence microscopy is a broadly used imaging technique that enhances the signal-to-noise ratio by removing out of focal plane fluorescence. Confocal microscopes come with a variety of modifications depending on the particular experimental goals. Microscopes, illumination pathways, and light collection were originally focused upon obtaining the highest resolution image possible, typically on fixed tissue. More recently, live-cell confocal imaging has gained importance. Since measured signals are often rapid or transient, thus requiring higher sampling rates, specializations are included to enhance spatial and temporal resolution while maintaining tissue viability. Thus, a balance between image quality, temporal resolution, and tissue viability is needed. A subtype of confocal imaging, termed swept field confocal (SFC) microscopy, can image live cells at high rates while maintaining confocality. SFC systems can use a pinhole array to obtain high spatial resolution, similar to spinning disc systems. In addition, SFC imaging can achieve faster rates by using a slit to sweep the light across the entire image plane, thus requiring a single scan to generate an image. Coupled to a high-speed charge-coupled device camera and a laser illumination source, images can be obtained at greater than 1,000 frames per second while maintaining confocality. PMID:22831554

  17. Underwater video enhancement using multi-camera super-resolution

    NASA Astrophysics Data System (ADS)

    Quevedo, E.; Delory, E.; Callicó, G. M.; Tobajas, F.; Sarmiento, R.

    2017-12-01

    Image spatial resolution is critical in several fields such as medicine, communications or satellite, and underwater applications. While a large variety of techniques for image restoration and enhancement has been proposed in the literature, this paper focuses on a novel Super-Resolution fusion algorithm based on a Multi-Camera environment that permits to enhance the quality of underwater video sequences without significantly increasing computation. In order to compare the quality enhancement, two objective quality metrics have been used: PSNR (Peak Signal-to-Noise Ratio) and the SSIM (Structural SIMilarity) index. Results have shown that the proposed method enhances the objective quality of several underwater sequences, avoiding the appearance of undesirable artifacts, with respect to basic fusion Super-Resolution algorithms.

  18. Resolution enhancement using simultaneous couple illumination

    NASA Astrophysics Data System (ADS)

    Hussain, Anwar; Martínez Fuentes, José Luis

    2016-10-01

    A super-resolution technique based on structured illumination created by a liquid crystal on silicon spatial light modulator (LCOS-SLM) is presented. Single and simultaneous pairs of tilted beams are generated to illuminate a target object. Resolution enhancement of an optical 4f system is demonstrated by using numerical simulations. The resulting intensity images are recorded at a charged couple device (CCD) and stored in the computer memory for further processing. One dimension enhancement can be performed with only 15 images. Two dimensional complete improvement requires 153 different images. The resolution of the optical system is extended three times compared to the band limited system.

  19. Spatial enhancement of ECG using diagnostic similarity score based lead selective multi-scale linear model.

    PubMed

    Nallikuzhy, Jiss J; Dandapat, S

    2017-06-01

    In this work, a new patient-specific approach to enhance the spatial resolution of ECG is proposed and evaluated. The proposed model transforms a three-lead ECG into a standard twelve-lead ECG thereby enhancing its spatial resolution. The three leads used for prediction are obtained from the standard twelve-lead ECG. The proposed model takes advantage of the improved inter-lead correlation in wavelet domain. Since the model is patient-specific, it also selects the optimal predictor leads for a given patient using a lead selection algorithm. The lead selection algorithm is based on a new diagnostic similarity score which computes the diagnostic closeness between the original and the spatially enhanced leads. Standard closeness measures are used to assess the performance of the model. The similarity in diagnostic information between the original and the spatially enhanced leads are evaluated using various diagnostic measures. Repeatability and diagnosability are performed to quantify the applicability of the model. A comparison of the proposed model is performed with existing models that transform a subset of standard twelve-lead ECG into the standard twelve-lead ECG. From the analysis of the results, it is evident that the proposed model preserves diagnostic information better compared to other models. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Recent Advances in 3D Time-Resolved Contrast-Enhanced MR Angiography

    PubMed Central

    Riederer, Stephen J.; Haider, Clifton R.; Borisch, Eric A.; Weavers, Paul T.; Young, Phillip M.

    2015-01-01

    Contrast-enhanced MR angiography (CE-MRA) was first introduced for clinical studies approximately 20 years ago. Early work provided 3 to 4 mm spatial resolution with acquisition times in the 30 sec range. Since that time there has been continuing effort to provide improved spatial resolution with reduced acquisition time, allowing high resolution three-dimensional (3D) time-resolved studies. The purpose of this work is to describe how this has been accomplished. Specific technical enablers have been: improved gradients allowing reduced repetition times, improved k-space sampling and reconstruction methods, parallel acquisition particularly in two directions, and improved and higher count receiver coil arrays. These have collectively made high resolution time-resolved studies readily available for many anatomic regions. Depending on the application, approximate 1 mm isotropic resolution is now possible with frame times of several seconds. Clinical applications of time-resolved CE-MRA are briefly reviewed. PMID:26032598

  1. Enhanced Satellite Remote Sensing of Coastal Waters Using Spatially Improved Bio-Optical Products from SNPP-VIIRS

    DTIC Science & Technology

    2015-01-01

    a spatial resolution of 250-m. The Gumley et al. computation for MODIS sharpening is given as a ratio of high to low resolution top of the atmosphere...NIR) correction (Stumpf, Arnone, Gould, Martinolich, & Ransibrahamanakul, 2003). Standard flagswere used tomask interference from land, clouds , sun...technique This new approach expands on the methodology described by Gumley et al. (2010), with somemodifications. We will compute a sim- ilar spatial

  2. Experimental characterization of a direct conversion amorphous selenium detector with thicker conversion layer for dual-energy contrast-enhanced breast imaging.

    PubMed

    Scaduto, David A; Tousignant, Olivier; Zhao, Wei

    2017-08-01

    Dual-energy contrast-enhanced imaging is being investigated as a tool to identify and localize angiogenesis in the breast, a possible indicator of malignant tumors. This imaging technique requires that x-ray images are acquired at energies above the k-shell binding energy of an appropriate radiocontrast agent. Iodinated contrast agents are commonly used for vascular imaging, and require x-ray energies greater than 33 keV. Conventional direct conversion amorphous selenium (a-Se) flat-panel imagers for digital mammography show suboptimal absorption efficiencies at these higher energies. We use spatial-frequency domain image quality metrics to evaluate the performance of a prototype direct conversion flat-panel imager with a thicker a-Se layer, specifically fabricated for dual-energy contrast-enhanced breast imaging. Imaging performance was evaluated in a prototype digital breast tomosynthesis (DBT) system. The spatial resolution, noise characteristics, detective quantum efficiency, and temporal performance of the detector were evaluated for dual-energy imaging for both conventional full-field digital mammography (FFDM) and DBT. The zero-frequency detective quantum efficiency of the prototype detector is improved by approximately 20% over the conventional detector for higher energy beams required for imaging with iodinated contrast agents. The effect of oblique entry of x-rays on spatial resolution does increase with increasing photoconductor thickness, specifically for the most oblique views of a DBT scan. Degradation of spatial resolution due to focal spot motion was also observed. Temporal performance was found to be comparable to conventional mammographic detectors. Increasing the a-Se thickness in direct conversion flat-panel imagers results in better performance for dual-energy contrast-enhanced breast imaging. The reduction in spatial resolution due to oblique entry of x-rays is appreciable in the most extreme clinically relevant cases, but may not profoundly affect reconstructed images due to the algorithms and filters employed. Degradation to projection domain spatial resolution is thus outweighed by the improvement in detective quantum efficiency for high-energy x-rays. © 2017 American Association of Physicists in Medicine.

  3. Resolution enhancement in integral microscopy by physical interpolation.

    PubMed

    Llavador, Anabel; Sánchez-Ortiga, Emilio; Barreiro, Juan Carlos; Saavedra, Genaro; Martínez-Corral, Manuel

    2015-08-01

    Integral-imaging technology has demonstrated its capability for computing depth images from the microimages recorded after a single shot. This capability has been shown in macroscopic imaging and also in microscopy. Despite the possibility of refocusing different planes from one snap-shot is crucial for the study of some biological processes, the main drawback in integral imaging is the substantial reduction of the spatial resolution. In this contribution we report a technique, which permits to increase the two-dimensional spatial resolution of the computed depth images in integral microscopy by a factor of √2. This is made by a double-shot approach, carried out by means of a rotating glass plate, which shifts the microimages in the sensor plane. We experimentally validate the resolution enhancement as well as we show the benefit of applying the technique to biological specimens.

  4. Resolution enhancement in integral microscopy by physical interpolation

    PubMed Central

    Llavador, Anabel; Sánchez-Ortiga, Emilio; Barreiro, Juan Carlos; Saavedra, Genaro; Martínez-Corral, Manuel

    2015-01-01

    Integral-imaging technology has demonstrated its capability for computing depth images from the microimages recorded after a single shot. This capability has been shown in macroscopic imaging and also in microscopy. Despite the possibility of refocusing different planes from one snap-shot is crucial for the study of some biological processes, the main drawback in integral imaging is the substantial reduction of the spatial resolution. In this contribution we report a technique, which permits to increase the two-dimensional spatial resolution of the computed depth images in integral microscopy by a factor of √2. This is made by a double-shot approach, carried out by means of a rotating glass plate, which shifts the microimages in the sensor plane. We experimentally validate the resolution enhancement as well as we show the benefit of applying the technique to biological specimens. PMID:26309749

  5. Integration of airborne Thematic Mapper Simulator (TMS) data and digitized aerial photography via an ISH transformation. [Intensity Saturation Hue

    NASA Technical Reports Server (NTRS)

    Ambrosia, Vincent G.; Myers, Jeffrey S.; Ekstrand, Robert E.; Fitzgerald, Michael T.

    1991-01-01

    A simple method for enhancing the spatial and spectral resolution of disparate data sets is presented. Two data sets, digitized aerial photography at a nominal spatial resolution 3,7 meters and TMS digital data at 24.6 meters, were coregistered through a bilinear interpolation to solve the problem of blocky pixel groups resulting from rectification expansion. The two data sets were then subjected to intensity-saturation-hue (ISH) transformations in order to 'blend' the high-spatial-resolution (3.7 m) digitized RC-10 photography with the high spectral (12-bands) and lower spatial (24.6 m) resolution TMS digital data. The resultant merged products make it possible to perform large-scale mapping, ease photointerpretation, and can be derived for any of the 12 available TMS spectral bands.

  6. Hyperspectral and multispectral data fusion based on linear-quadratic nonnegative matrix factorization

    NASA Astrophysics Data System (ADS)

    Benhalouche, Fatima Zohra; Karoui, Moussa Sofiane; Deville, Yannick; Ouamri, Abdelaziz

    2017-04-01

    This paper proposes three multisharpening approaches to enhance the spatial resolution of urban hyperspectral remote sensing images. These approaches, related to linear-quadratic spectral unmixing techniques, use a linear-quadratic nonnegative matrix factorization (NMF) multiplicative algorithm. These methods begin by unmixing the observable high-spectral/low-spatial resolution hyperspectral and high-spatial/low-spectral resolution multispectral images. The obtained high-spectral/high-spatial resolution features are then recombined, according to the linear-quadratic mixing model, to obtain an unobservable multisharpened high-spectral/high-spatial resolution hyperspectral image. In the first designed approach, hyperspectral and multispectral variables are independently optimized, once they have been coherently initialized. These variables are alternately updated in the second designed approach. In the third approach, the considered hyperspectral and multispectral variables are jointly updated. Experiments, using synthetic and real data, are conducted to assess the efficiency, in spatial and spectral domains, of the designed approaches and of linear NMF-based approaches from the literature. Experimental results show that the designed methods globally yield very satisfactory spectral and spatial fidelities for the multisharpened hyperspectral data. They also prove that these methods significantly outperform the used literature approaches.

  7. Achieving superresolution with illumination-enhanced sparsity.

    PubMed

    Yu, Jiun-Yann; Becker, Stephen R; Folberth, James; Wallin, Bruce F; Chen, Simeng; Cogswell, Carol J

    2018-04-16

    Recent advances in superresolution fluorescence microscopy have been limited by a belief that surpassing two-fold resolution enhancement of the Rayleigh resolution limit requires stimulated emission or the fluorophore to undergo state transitions. Here we demonstrate a new superresolution method that requires only image acquisitions with a focused illumination spot and computational post-processing. The proposed method utilizes the focused illumination spot to effectively reduce the object size and enhance the object sparsity and consequently increases the resolution and accuracy through nonlinear image post-processing. This method clearly resolves 70nm resolution test objects emitting ~530nm light with a 1.4 numerical aperture (NA) objective, and, when imaging through a 0.5NA objective, exhibits high spatial frequencies comparable to a 1.4NA widefield image, both demonstrating a resolution enhancement above two-fold of the Rayleigh resolution limit. More importantly, we examine how the resolution increases with photon numbers, and show that the more-than-two-fold enhancement is achievable with realistic photon budgets.

  8. [Non-contrast time-resolved magnetic resonance angiography combining high resolution multiple phase echo planar imaging based signal targeting and alternating radiofrequency contrast inherent inflow enhanced multi phase angiography combining spatial resolution echo planar imaging based signal targeting and alternating radiofrequency in intracranial arteries].

    PubMed

    Nakamura, Masanobu; Yoneyama, Masami; Tabuchi, Takashi; Takemura, Atsushi; Obara, Makoto; Sawano, Seishi

    2012-01-01

    Detailed information on anatomy and hemodynamics in cerebrovascular disorders such as AVM and Moyamoya disease is mandatory for defined diagnosis and treatment planning. Arterial spin labeling technique has come to be applied to magnetic resonance angiography (MRA) and perfusion imaging in recent years. However, those non-contrast techniques are mostly limited to single frame images. Recently we have proposed a non-contrast time-resolved MRA technique termed contrast inherent inflow enhanced multi phase angiography combining spatial resolution echo planar imaging based signal targeting and alternating radiofrequency (CINEMA-STAR). CINEMA-STAR can extract the blood flow in the major intracranial arteries at an interval of 70 ms and thus permits us to observe vascular construction in full by preparing MIP images of axial acquisitions with high spatial resolution. This preliminary study demonstrates the usefulness of the CINEMA-STAR technique in evaluating the cerebral vasculature.

  9. Characterization and modelling of the spatially- and spectrally-varying point-spread function in hyperspectral imaging systems for computational correction of axial optical aberrations

    NASA Astrophysics Data System (ADS)

    Špiclin, Žiga; Bürmen, Miran; Pernuš, Franjo; Likar, Boštjan

    2012-03-01

    Spatial resolution of hyperspectral imaging systems can vary significantly due to axial optical aberrations that originate from wavelength-induced index-of-refraction variations of the imaging optics. For systems that have a broad spectral range, the spatial resolution will vary significantly both with respect to the acquisition wavelength and with respect to the spatial position within each spectral image. Variations of the spatial resolution can be effectively characterized as part of the calibration procedure by a local image-based estimation of the pointspread function (PSF) of the hyperspectral imaging system. The estimated PSF can then be used in the image deconvolution methods to improve the spatial resolution of the spectral images. We estimated the PSFs from the spectral images of a line grid geometric caliber. From individual line segments of the line grid, the PSF was obtained by a non-parametric estimation procedure that used an orthogonal series representation of the PSF. By using the non-parametric estimation procedure, the PSFs were estimated at different spatial positions and at different wavelengths. The variations of the spatial resolution were characterized by the radius and the fullwidth half-maximum of each PSF and by the modulation transfer function, computed from images of USAF1951 resolution target. The estimation and characterization of the PSFs and the image deconvolution based spatial resolution enhancement were tested on images obtained by a hyperspectral imaging system with an acousto-optic tunable filter in the visible spectral range. The results demonstrate that the spatial resolution of the acquired spectral images can be significantly improved using the estimated PSFs and image deconvolution methods.

  10. Multicontrast reconstruction using compressed sensing with low rank and spatially varying edge-preserving constraints for high-resolution MR characterization of myocardial infarction.

    PubMed

    Zhang, Li; Athavale, Prashant; Pop, Mihaela; Wright, Graham A

    2017-08-01

    To enable robust reconstruction for highly accelerated three-dimensional multicontrast late enhancement imaging to provide improved MR characterization of myocardial infarction with isotropic high spatial resolution. A new method using compressed sensing with low rank and spatially varying edge-preserving constraints (CS-LASER) is proposed to improve the reconstruction of fine image details from highly undersampled data. CS-LASER leverages the low rank feature of the multicontrast volume series in MR relaxation and integrates spatially varying edge preservation into the explicit low rank constrained compressed sensing framework using weighted total variation. With an orthogonal temporal basis pre-estimated, a multiscale iterative reconstruction framework is proposed to enable the practice of CS-LASER with spatially varying weights of appropriate accuracy. In in vivo pig studies with both retrospective and prospective undersamplings, CS-LASER preserved fine image details better and presented tissue characteristics with a higher degree of consistency with histopathology, particularly in the peri-infarct region, than an alternative technique for different acceleration rates. An isotropic resolution of 1.5 mm was achieved in vivo within a single breath-hold using the proposed techniques. Accelerated three-dimensional multicontrast late enhancement with CS-LASER can achieve improved MR characterization of myocardial infarction with high spatial resolution. Magn Reson Med 78:598-610, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  11. Tagged Neutron Source for API Inspection Systems with Greatly Enhanced Spatial Resolution

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2012-06-04

    We recently developed induced fission and transmission imaging methods with time- and directionally-tagged neutrons offer new capabilities for characterization of fissile material configurations and enhanced detection of special nuclear materials (SNM). An Advanced Associated Particle Imaging (API) generator with higher angular resolution and neutron yield than existing systems is needed to fully exploit these methods.

  12. Spatially-controlled illumination with rescan confocal microscopy enhances image quality, resolution and reduces photodamage

    NASA Astrophysics Data System (ADS)

    Krishnaswami, Venkataraman; De Luca, Giulia M. R.; Breedijk, Ronald M. P.; Van Noorden, Cornelis J. F.; Manders, Erik M. M.; Hoebe, Ron A.

    2017-02-01

    Fluorescence microscopy is an important tool in biomedical imaging. An inherent trade-off lies between image quality and photodamage. Recently, we have introduced rescan confocal microscopy (RCM) that improves the lateral resolution of a confocal microscope down to 170 nm. Previously, we have demonstrated that with controlled-light exposure microscopy, spatial control of illumination reduces photodamage without compromising image quality. Here, we show that the combination of these two techniques leads to high resolution imaging with reduced photodamage without compromising image quality. Implementation of spatially-controlled illumination was carried out in RCM using a line scanning-based approach. Illumination is spatially-controlled for every line during imaging with the help of a prediction algorithm that estimates the spatial profile of the fluorescent specimen. The estimation is based on the information available from previously acquired line images. As a proof-of-principle, we show images of N1E-115 neuroblastoma cells, obtained by this new setup with reduced illumination dose, improved resolution and without compromising image quality.

  13. Spatial resolution versus contrast trade-off enhancement in high-resolution surface plasmon resonance imaging (SPRI) by metal surface nanostructure design.

    PubMed

    Banville, Frederic A; Moreau, Julien; Sarkar, Mitradeep; Besbes, Mondher; Canva, Michael; Charette, Paul G

    2018-04-16

    Surface plasmon resonance imaging (SPRI) is an optical near-field method used for mapping the spatial distribution of chemical/physical perturbations above a metal surface without exogenous labeling. Currently, the majority of SPRI systems are used in microarray biosensing, requiring only modest spatial resolution. There is increasing interest in applying SPRI for label-free near-field imaging of biological cells to study cell/surface interactions. However, the required resolution (sub-µm) greatly exceeds what current systems can deliver. Indeed, the attenuation length of surface plasmon polaritons (SPP) severely limits resolution along one axis, typically to tens of µm. Strategies to date for improving spatial resolution result in a commensurate deterioration in other imaging parameters. Unlike the smooth metal surfaces used in SPRI that support purely propagating surface modes, nanostructured metal surfaces support "hybrid" SPP modes that share attributes from both propagating and localized modes. We show that these hybrid modes are especially well-suited to high-resolution imaging and demonstrate how the nanostructure geometry can be designed to achieve sub-µm resolution while mitigating the imaging parameter trade-off according to an application-specific optimum.

  14. Landsat 7 thermal-IR image sharpening using an artificial neural network and sensor model

    USGS Publications Warehouse

    Lemeshewsky, G.P.; Schowengerdt, R.A.; ,

    2001-01-01

    The enhanced thematic mapper (plus) (ETM+) instrument on Landsat 7 shares the same basic design as the TM sensors on Landsats 4 and 5, with some significant improvements. In common are six multispectral bands with a 30-m ground-projected instantaneous field of view (GIFOV). However, the thermaL-IR (TIR) band now has a 60-m GIFOV, instead of 120-m. Also, a 15-m panchromatic band has been added. The artificial neural network (NN) image sharpening method described here uses data from the higher spatial resolution ETM+ bands to enhance (sharpen) the spatial resolution of the TIR imagery. It is based on an assumed correlation over multiple scales of resolution, between image edge contrast patterns in the TIR band and several other spectral bands. A multilayer, feedforward NN is trained to approximate TIR data at 60m, given degraded (from 30-m to 60-m) spatial resolution input from spectral bands 7, 5, and 2. After training, the NN output for full-resolution input generates an approximation of a TIR image at 30-m resolution. Two methods are used to degrade the spatial resolution of the imagery used for NN training, and the corresponding sharpening results are compared. One degradation method uses a published sensor transfer function (TF) for Landsat 5 to simulate sensor coarser resolution imagery from higher resolution imagery. For comparison, the second degradation method is simply Gaussian low pass filtering and subsampling, wherein the Gaussian filter approximates the full width at half maximum amplitude characteristics of the TF-based spatial filter. Two fixed-size NNs (that is, number of weights and processing elements) were trained separately with the degraded resolution data, and the sharpening results compared. The comparison evaluates the relative influence of the degradation technique employed and whether or not it is desirable to incorporate a sensor TF model. Preliminary results indicate some improvements for the sensor model-based technique. Further evaluation using a higher resolution reference image and strict application of sensor model to data is recommended.

  15. Ultrafast Bilateral DCE-MRI of the Breast with Conventional Fourier Sampling: Preliminary Evaluation of Semi-quantitative Analysis.

    PubMed

    Pineda, Federico D; Medved, Milica; Wang, Shiyang; Fan, Xiaobing; Schacht, David V; Sennett, Charlene; Oto, Aytekin; Newstead, Gillian M; Abe, Hiroyuki; Karczmar, Gregory S

    2016-09-01

    The study aimed to evaluate the feasibility and advantages of a combined high temporal and high spatial resolution protocol for dynamic contrast-enhanced magnetic resonance imaging of the breast. Twenty-three patients with enhancing lesions were imaged at 3T. The acquisition protocol consisted of a series of bilateral, fat-suppressed "ultrafast" acquisitions, with 6.9- to 9.9-second temporal resolution for the first minute following contrast injection, followed by four high spatial resolution acquisitions with 60- to 79.5-second temporal resolution. All images were acquired with standard uniform Fourier sampling. A filtering method was developed to reduce noise and detect significant enhancement in the high temporal resolution images. Time of arrival (TOA) was defined as the time at which each voxel first satisfied all the filter conditions, relative to the time of initial arterial enhancement. Ultrafast images improved visualization of the vasculature feeding and draining lesions. A small percentage of the entire field of view (<6%) enhanced significantly in the 30 seconds following contrast injection. Lesion conspicuity was highest in early ultrafast images, especially in cases with marked parenchymal enhancement. Although the sample size was relatively small, the average TOA for malignant lesions was significantly shorter than the TOA for benign lesions. Significant differences were also measured in other parameters descriptive of early contrast media uptake kinetics (P < 0.05). Ultrafast imaging in the first minute of dynamic contrast-enhanced magnetic resonance imaging of the breast has the potential to add valuable information on early contrast dynamics. Ultrafast imaging could allow radiologists to confidently identify lesions in the presence of marked background parenchymal enhancement. Copyright © 2016 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  16. A Spatio-Temporal Enhancement Method for medium resolution LAI (STEM-LAI)

    NASA Astrophysics Data System (ADS)

    Houborg, Rasmus; McCabe, Matthew F.; Gao, Feng

    2016-05-01

    Satellite remote sensing has been used successfully to map leaf area index (LAI) across landscapes, but advances are still needed to exploit multi-scale data streams for producing LAI at both high spatial and temporal resolution. A multi-scale Spatio-Temporal Enhancement Method for medium resolution LAI (STEM-LAI) has been developed to generate 4-day time-series of Landsat-scale LAI from existing medium resolution LAI products. STEM-LAI has been designed to meet the demands of applications requiring frequent and spatially explicit information, such as effectively resolving rapidly evolving vegetation dynamics at sub-field (30 m) scales. In this study, STEM-LAI is applied to Moderate Resolution Imaging Spectroradiometer (MODIS) based LAI data and utilizes a reference-based regression tree approach for producing MODIS-consistent, but Landsat-based, LAI. The Spatial and Temporal Adaptive Reflectance Fusion Model (STARFM) is used to interpolate the downscaled LAI between Landsat acquisition dates, providing a high spatial and temporal resolution improvement over existing LAI products. STARFM predicts high resolution LAI by blending MODIS and Landsat based information from a common acquisition date, with MODIS data from a prediction date. To demonstrate its capacity to reproduce fine-scale spatial features observed in actual Landsat LAI, the STEM-LAI approach is tested over an agricultural region in Nebraska. The implementation of a 250 m resolution LAI product, derived from MODIS 1 km data and using a scale consistent approach based on the Normalized Difference Vegetation Index (NDVI), is found to significantly improve accuracies of spatial pattern prediction, with the coefficient of efficiency (E) ranging from 0.77-0.94 compared to 0.01-0.85 when using 1 km LAI inputs alone. Comparisons against an 11-year record of in-situ measured LAI over maize and soybean highlight the utility of STEM-LAI in reproducing observed LAI dynamics (both characterized by r2 = 0.86) over a range of plant development stages. Overall, STEM-LAI represents an effective downscaling and temporal enhancement mechanism that predicts in-situ measured LAI better than estimates derived through linear interpolation between Landsat acquisitions. This is particularly true when the in-situ measurement date is greater than 10 days from the nearest Landsat acquisition, with prediction errors reduced by up to 50%. With a streamlined and completely automated processing interface, STEM-LAI represents a flexible tool for LAI disaggregation in space and time that is adaptable to different land cover types, landscape heterogeneities, and cloud cover conditions.

  17. 3D undersampled golden-radial phase encoding for DCE-MRA using inherently regularized iterative SENSE.

    PubMed

    Prieto, Claudia; Uribe, Sergio; Razavi, Reza; Atkinson, David; Schaeffter, Tobias

    2010-08-01

    One of the current limitations of dynamic contrast-enhanced MR angiography is the requirement of both high spatial and high temporal resolution. Several undersampling techniques have been proposed to overcome this problem. However, in most of these methods the tradeoff between spatial and temporal resolution is constant for all the time frames and needs to be specified prior to data collection. This is not optimal for dynamic contrast-enhanced MR angiography where the dynamics of the process are difficult to predict and the image quality requirements are changing during the bolus passage. Here, we propose a new highly undersampled approach that allows the retrospective adaptation of the spatial and temporal resolution. The method combines a three-dimensional radial phase encoding trajectory with the golden angle profile order and non-Cartesian Sensitivity Encoding (SENSE) reconstruction. Different regularization images, obtained from the same acquired data, are used to stabilize the non-Cartesian SENSE reconstruction for the different phases of the bolus passage. The feasibility of the proposed method was demonstrated on a numerical phantom and in three-dimensional intracranial dynamic contrast-enhanced MR angiography of healthy volunteers. The acquired data were reconstructed retrospectively with temporal resolutions from 1.2 sec to 8.1 sec, providing a good depiction of small vessels, as well as distinction of different temporal phases.

  18. Hybrid Image Fusion for Sharpness Enhancement of Multi-Spectral Lunar Images

    NASA Astrophysics Data System (ADS)

    Awumah, Anna; Mahanti, Prasun; Robinson, Mark

    2016-10-01

    Image fusion enhances the sharpness of a multi-spectral (MS) image by incorporating spatial details from a higher-resolution panchromatic (Pan) image [1,2]. Known applications of image fusion for planetary images are rare, although image fusion is well-known for its applications to Earth-based remote sensing. In a recent work [3], six different image fusion algorithms were implemented and their performances were verified with images from the Lunar Reconnaissance Orbiter (LRO) Camera. The image fusion procedure obtained a high-resolution multi-spectral (HRMS) product from the LRO Narrow Angle Camera (used as Pan) and LRO Wide Angle Camera (used as MS) images. The results showed that the Intensity-Hue-Saturation (IHS) algorithm results in a high-spatial quality product while the Wavelet-based image fusion algorithm best preserves spectral quality among all the algorithms. In this work we show the results of a hybrid IHS-Wavelet image fusion algorithm when applied to LROC MS images. The hybrid method provides the best HRMS product - both in terms of spatial resolution and preservation of spectral details. Results from hybrid image fusion can enable new science and increase the science return from existing LROC images.[1] Pohl, Cle, and John L. Van Genderen. "Review article multisensor image fusion in remote sensing: concepts, methods and applications." International journal of remote sensing 19.5 (1998): 823-854.[2] Zhang, Yun. "Understanding image fusion." Photogramm. Eng. Remote Sens 70.6 (2004): 657-661.[3] Mahanti, Prasun et al. "Enhancement of spatial resolution of the LROC Wide Angle Camera images." Archives, XXIII ISPRS Congress Archives (2016).

  19. On the assessment of spatial resolution of PET systems with iterative image reconstruction

    NASA Astrophysics Data System (ADS)

    Gong, Kuang; Cherry, Simon R.; Qi, Jinyi

    2016-03-01

    Spatial resolution is an important metric for performance characterization in PET systems. Measuring spatial resolution is straightforward with a linear reconstruction algorithm, such as filtered backprojection, and can be performed by reconstructing a point source scan and calculating the full-width-at-half-maximum (FWHM) along the principal directions. With the widespread adoption of iterative reconstruction methods, it is desirable to quantify the spatial resolution using an iterative reconstruction algorithm. However, the task can be difficult because the reconstruction algorithms are nonlinear and the non-negativity constraint can artificially enhance the apparent spatial resolution if a point source image is reconstructed without any background. Thus, it was recommended that a background should be added to the point source data before reconstruction for resolution measurement. However, there has been no detailed study on the effect of the point source contrast on the measured spatial resolution. Here we use point source scans from a preclinical PET scanner to investigate the relationship between measured spatial resolution and the point source contrast. We also evaluate whether the reconstruction of an isolated point source is predictive of the ability of the system to resolve two adjacent point sources. Our results indicate that when the point source contrast is below a certain threshold, the measured FWHM remains stable. Once the contrast is above the threshold, the measured FWHM monotonically decreases with increasing point source contrast. In addition, the measured FWHM also monotonically decreases with iteration number for maximum likelihood estimate. Therefore, when measuring system resolution with an iterative reconstruction algorithm, we recommend using a low-contrast point source and a fixed number of iterations.

  20. Ultra high spatial and temporal resolution breast imaging at 7T.

    PubMed

    van de Bank, B L; Voogt, I J; Italiaander, M; Stehouwer, B L; Boer, V O; Luijten, P R; Klomp, D W J

    2013-04-01

    There is a need to obtain higher specificity in the detection of breast lesions using MRI. To address this need, Dynamic Contrast-Enhanced (DCE) MRI has been combined with other structural and functional MRI techniques. Unfortunately, owing to time constraints structural images at ultra-high spatial resolution can generally not be obtained during contrast uptake, whereas the relatively low spatial resolution of functional imaging (e.g. diffusion and perfusion) limits the detection of small lesions. To be able to increase spatial as well as temporal resolution simultaneously, the sensitivity of MR detection needs to increase as well as the ability to effectively accelerate the acquisition. The required gain in signal-to-noise ratio (SNR) can be obtained at 7T, whereas acceleration can be obtained with high-density receiver coil arrays. In this case, morphological imaging can be merged with DCE-MRI, and other functional techniques can be obtained at higher spatial resolution, and with less distortion [e.g. Diffusion Weighted Imaging (DWI)]. To test the feasibility of this concept, we developed a unilateral breast coil for 7T. It comprises a volume optimized dual-channel transmit coil combined with a 30-channel receive array coil. The high density of small coil elements enabled efficient acceleration in any direction to acquire ultra high spatial resolution MRI of close to 0.6 mm isotropic detail within a temporal resolution of 69 s, high spatial resolution MRI of 1.5 mm isotropic within an ultra high temporal resolution of 6.7 s and low distortion DWI at 7T, all validated in phantoms, healthy volunteers and a patient with a lesion in the right breast classified as Breast Imaging Reporting and Data System (BI-RADS) IV. Copyright © 2012 John Wiley & Sons, Ltd.

  1. Tip-enhanced Raman mapping with top-illumination AFM.

    PubMed

    Chan, K L Andrew; Kazarian, Sergei G

    2011-04-29

    Tip-enhanced Raman mapping is a powerful, emerging technique that offers rich chemical information and high spatial resolution. Currently, most of the successes in tip-enhanced Raman scattering (TERS) measurements are based on the inverted configuration where tips and laser are approaching the sample from opposite sides. This results in the limitation of measurement for transparent samples only. Several approaches have been developed to obtain tip-enhanced Raman mapping in reflection mode, many of which involve certain customisations of the system. We have demonstrated in this work that it is also possible to obtain TERS nano-images using an upright microscope (top-illumination) with a gold-coated Si atomic force microscope (AFM) cantilever without significant modification to the existing integrated AFM/Raman system. A TERS image of a single-walled carbon nanotube has been achieved with a spatial resolution of ∼ 20-50 nm, demonstrating the potential of this technique for studying non-transparent nanoscale materials.

  2. Solid immersion lenses for enhancing the optical resolution of thermal and electroluminescence mapping of GaN-on-SiC transistors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pomeroy, J. W., E-mail: James.Pomeroy@Bristol.ac.uk; Kuball, M.

    2015-10-14

    Solid immersion lenses (SILs) are shown to greatly enhance optical spatial resolution when measuring AlGaN/GaN High Electron Mobility Transistors (HEMTs), taking advantage of the high refractive index of the SiC substrates commonly used for these devices. Solid immersion lenses can be applied to techniques such as electroluminescence emission microscopy and Raman thermography, aiding the development device physics models. Focused ion beam milling is used to fabricate solid immersion lenses in SiC substrates with a numerical aperture of 1.3. A lateral spatial resolution of 300 nm is demonstrated at an emission wavelength of 700 nm, and an axial spatial resolution of 1.7 ± 0.3 μm atmore » a laser wavelength of 532 nm is demonstrated; this is an improvement of 2.5× and 5×, respectively, when compared with a conventional 0.5 numerical aperture objective lens without a SIL. These results highlight the benefit of applying the solid immersion lenses technique to the optical characterization of GaN HEMTs. Further improvements may be gained through aberration compensation and increasing the SIL numerical aperture.« less

  3. Light-sheet enhanced resolution of light field microscopy for rapid imaging of large volumes

    NASA Astrophysics Data System (ADS)

    Madrid Wolff, Jorge; Castro, Diego; Arbeláez, Pablo; Forero-Shelton, Manu

    2018-02-01

    Whole-brain imaging is challenging because it demands microscopes with high temporal and spatial resolution, which are often at odds, especially in the context of large fields of view. We have designed and built a light-sheet microscope with digital micromirror illumination and light-field detection. On the one hand, light sheets provide high resolution optical sectioning on live samples without compromising their viability. On the other hand, light field imaging makes it possible to reconstruct full volumes of relatively large fields of view from a single camera exposure; however, its enhanced temporal resolution comes at the expense of spatial resolution, limiting its applicability. We present an approach to increase the resolution of light field images using DMD-based light sheet illumination. To that end, we develop a method to produce synthetic resolution targets for light field microscopy and a procedure to correct the depth at which planes are refocused with rendering software. We measured the axial resolution as a function of depth and show a three-fold potential improvement with structured illumination, albeit by sacrificing some temporal resolution, also three-fold. This results in an imaging system that may be adjusted to specific needs without having to reassemble and realign it. This approach could be used to image relatively large samples at high rates.

  4. Particle detector spatial resolution

    DOEpatents

    Perez-Mendez, V.

    1992-12-15

    Method and apparatus for producing separated columns of scintillation layer material, for use in detection of X-rays and high energy charged particles with improved spatial resolution is disclosed. A pattern of ridges or projections is formed on one surface of a substrate layer or in a thin polyimide layer, and the scintillation layer is grown at controlled temperature and growth rate on the ridge-containing material. The scintillation material preferentially forms cylinders or columns, separated by gaps conforming to the pattern of ridges, and these columns direct most of the light produced in the scintillation layer along individual columns for subsequent detection in a photodiode layer. The gaps may be filled with a light-absorbing material to further enhance the spatial resolution of the particle detector. 12 figs.

  5. Particle detector spatial resolution

    DOEpatents

    Perez-Mendez, Victor

    1992-01-01

    Method and apparatus for producing separated columns of scintillation layer material, for use in detection of X-rays and high energy charged particles with improved spatial resolution. A pattern of ridges or projections is formed on one surface of a substrate layer or in a thin polyimide layer, and the scintillation layer is grown at controlled temperature and growth rate on the ridge-containing material. The scintillation material preferentially forms cylinders or columns, separated by gaps conforming to the pattern of ridges, and these columns direct most of the light produced in the scintillation layer along individual columns for subsequent detection in a photodiode layer. The gaps may be filled with a light-absorbing material to further enhance the spatial resolution of the particle detector.

  6. [Detection of single-walled carbon nanotube bundles by tip-enhanced Raman spectroscopy].

    PubMed

    Wu, Xiao-Bin; Wang, Jia; Wang, Rui; Xu, Ji-Ying; Tian, Qian; Yu, Jian-Yuan

    2009-10-01

    Raman spectroscopy is a powerful technique in the characterization of carbon nanotubes (CNTs). However, this spectral method is subject to two obstacles. One is spatial resolution, namely the diffraction limits of light, and the other is its inherent small Raman cross section and weak signal. To resolve these problems, a new approach has been developed, denoted tip-enhanced Raman spectroscopy (TERS). TERS has been demonstrated to be a powerful spectroscopic and microscopic technique to characterize nanomaterial or nanostructures. Excited by a focused laser beam, an enhanced electric field is generated in the vicinity of a metallic tip because of the surface plasmon polariton (SPP) and lightening rod effect. Consequently, Raman signal from the sample area illuminated by the enhanced field nearby the tip is enhanced. At the same time, the topography is obtained in the nanometer scale. The exact corresponding relationship between the localized Raman and the topography makes the Raman identification at the nanometer scale to be feasible. In the present paper, based on an inverted microscope and a metallic AFM tip, a tip-enhanced Raman system was set up. The radius of the Au-coated metallic tip is about 30 nm. The 532 nm laser passes through a high numerical objective (NA0.95) from the bottom to illuminate the tip to excite the enhanced electric field. Corresponding with the AFM image, the tip-enhanced near-field Raman of a 100 nm diameter single-walled carbon nanotube (SWNT) bundles was obtained. The SWNTs were prepared by arc method. Furthermore, the near-field Raman of about 3 SWNTs of the bundles was received with the spatial resolution beyond the diffraction limit. Compared with the far-field Raman, the enhancement factor of the tip-enhanced Raman is more than 230. With the super-diffraction spatial resolution and the tip-enhanced Raman ability, tip-enhanced Raman spectroscopy will play an important role in the nano-material and nano-structure characterization.

  7. The use of Sentinel-2 imagery for seagrass mapping: Kalloni Gulf (Lesvos Island, Greece) case study

    NASA Astrophysics Data System (ADS)

    Topouzelis, Konstantinos; Charalampis Spondylidis, Spyridon; Papakonstantinou, Apostolos; Soulakellis, Nikolaos

    2016-08-01

    Seagrass meadows play a significant role in ecosystems by stabilizing sediment and improving water clarity, which enhances seagrass growing conditions. It is high on the priority of EU legislation to map and protect them. The traditional use of medium spatial resolution satellite imagery e.g. Landsat-8 (30m) is very useful for mapping seagrass meadows on a regional scale. However, the availability of Sentinel-2 data, the recent ESA's satellite with its payload Multi-Spectral Instrument (MSI) is expected to improve the mapping accuracy. MSI designed to improve coastline studies due to its enhanced spatial and spectral capabilities e.g. optical bands with 10m spatial resolution. The present work examines the quality of Sentinel-2 images for seagrass mapping, the ability of each band in detection and discrimination of different habitats and estimates the accuracy of seagrass mapping. After pre-processing steps, e.g. radiometric calibration and atmospheric correction, image classified into four classes. Classification classes included sub-bottom composition e.g. seagrass, soft bottom, and hard bottom. Concrete vectors describing the areas covered by seagrass extracted from the high-resolution satellite image and used as in situ measurements. The developed methodology applied in the Gulf of Kalloni, (Lesvos Island - Greece). Results showed that Sentinel-2 images can be robustly used for seagrass mapping due to their spatial resolution, band availability and radiometric accuracy.

  8. Spatial resolution of a hard x-ray CCD detector.

    PubMed

    Seely, John F; Pereira, Nino R; Weber, Bruce V; Schumer, Joseph W; Apruzese, John P; Hudson, Lawrence T; Szabo, Csilla I; Boyer, Craig N; Skirlo, Scott

    2010-08-10

    The spatial resolution of an x-ray CCD detector was determined from the widths of the tungsten x-ray lines in the spectrum formed by a crystal spectrometer in the 58 to 70 keV energy range. The detector had 20 microm pixel, 1700 by 1200 pixel format, and a CsI x-ray conversion scintillator. The spectral lines from a megavolt x-ray generator were focused on the spectrometer's Rowland circle by a curved transmission crystal. The line shapes were Lorentzian with an average width after removal of the natural and instrumental line widths of 95 microm (4.75 pixels). A high spatial frequency background, primarily resulting from scattered gamma rays, was removed from the spectral image by Fourier analysis. The spectral lines, having low spatial frequency in the direction perpendicular to the dispersion, were enhanced by partially removing the Lorentzian line shape and by fitting Lorentzian curves to broad unresolved spectral features. This demonstrates the ability to improve the spectral resolution of hard x-ray spectra that are recorded by a CCD detector with well-characterized intrinsic spatial resolution.

  9. Max CAPR: high-resolution 3D contrast-enhanced MR angiography with acquisition times under 5 seconds.

    PubMed

    Haider, Clifton R; Borisch, Eric A; Glockner, James F; Mostardi, Petrice M; Rossman, Phillip J; Young, Phillip M; Riederer, Stephen J

    2010-10-01

    High temporal and spatial resolution is desired in imaging of vascular abnormalities having short arterial-to-venous transit times. Methods that exploit temporal correlation to reduce the observed frame time demonstrate temporal blurring, obfuscating bolus dynamics. Previously, a Cartesian acquisition with projection reconstruction-like (CAPR) sampling method has been demonstrated for three-dimensional contrast-enhanced angiographic imaging of the lower legs using two-dimensional sensitivity-encoding acceleration and partial Fourier acceleration, providing 1mm isotropic resolution of the calves, with 4.9-sec frame time and 17.6-sec temporal footprint. In this work, the CAPR acquisition is further undersampled to provide a net acceleration approaching 40 by eliminating all view sharing. The tradeoff of frame time and temporal footprint in view sharing is presented and characterized in phantom experiments. It is shown that the resultant 4.9-sec acquisition time, three-dimensional images sets have sufficient spatial and temporal resolution to clearly portray arterial and venous phases of contrast passage. It is further hypothesized that these short temporal footprint sequences provide diagnostic quality images. This is tested and shown in a series of nine contrast-enhanced MR angiography patient studies performed with the new method.

  10. Enhanced Sensitivity for High Spatial Resolution Lipid Analysis by Negative Ion Mode MALDI Imaging Mass Spectrometry

    PubMed Central

    Angel, Peggi M.; Spraggins, Jeffrey M.; Baldwin, H. Scott; Caprioli, Richard

    2012-01-01

    We have achieved enhanced lipid imaging to a ~10 μm spatial resolution using negative ion mode matrix assisted laser desorption ionization (MALDI) imaging mass spectrometry, sublimation of 2,5-dihydroxybenzoic acid as the MALDI matrix and a sample preparation protocol that uses aqueous washes. We report on the effect of treating tissue sections by washing with volatile buffers at different pHs prior to negative ion mode lipid imaging. The results show that washing with ammonium formate, pH 6.4, or ammonium acetate, pH 6.7, significantly increases signal intensity and number of analytes recorded from adult mouse brain tissue sections. Major lipid species measured were glycerophosphoinositols, glycerophosphates, glycerolphosphoglycerols, glycerophosphoethanolamines, glycerophospho-serines, sulfatides, and gangliosides. Ion images from adult mouse brain sections that compare washed and unwashed sections are presented and show up to fivefold increases in ion intensity for washed tissue. The sample preparation protocol has been found to be applicable across numerous organ types and significantly expands the number of lipid species detectable by imaging mass spectrometry at high spatial resolution. PMID:22243218

  11. Towards sub-nanometer real-space observation of spin and orbital magnetism at the Fe/MgO interface

    PubMed Central

    Thersleff, Thomas; Muto, Shunsuke; Werwiński, Mirosław; Spiegelberg, Jakob; Kvashnin, Yaroslav; Hjӧrvarsson, Björgvin; Eriksson, Olle; Rusz, Ján; Leifer, Klaus

    2017-01-01

    While the performance of magnetic tunnel junctions based on metal/oxide interfaces is determined by hybridization, charge transfer, and magnetic properties at the interface, there are currently only limited experimental techniques with sufficient spatial resolution to directly observe these effects simultaneously in real-space. In this letter, we demonstrate an experimental method based on Electron Magnetic Circular Dichroism (EMCD) that will allow researchers to simultaneously map magnetic transitions and valency in real-space over interfacial cross-sections with sub-nanometer spatial resolution. We apply this method to an Fe/MgO bilayer system, observing a significant enhancement in the orbital to spin moment ratio that is strongly localized to the interfacial region. Through the use of first-principles calculations, multivariate statistical analysis, and Electron Energy-Loss Spectroscopy (EELS), we explore the extent to which this enhancement can be attributed to emergent magnetism due to structural confinement at the interface. We conclude that this method has the potential to directly visualize spin and orbital moments at buried interfaces in magnetic systems with unprecedented spatial resolution. PMID:28338011

  12. Towards sub-nanometer real-space observation of spin and orbital magnetism at the Fe/MgO interface

    NASA Astrophysics Data System (ADS)

    Thersleff, Thomas; Muto, Shunsuke; Werwiński, Mirosław; Spiegelberg, Jakob; Kvashnin, Yaroslav; Hjӧrvarsson, Björgvin; Eriksson, Olle; Rusz, Ján; Leifer, Klaus

    2017-03-01

    While the performance of magnetic tunnel junctions based on metal/oxide interfaces is determined by hybridization, charge transfer, and magnetic properties at the interface, there are currently only limited experimental techniques with sufficient spatial resolution to directly observe these effects simultaneously in real-space. In this letter, we demonstrate an experimental method based on Electron Magnetic Circular Dichroism (EMCD) that will allow researchers to simultaneously map magnetic transitions and valency in real-space over interfacial cross-sections with sub-nanometer spatial resolution. We apply this method to an Fe/MgO bilayer system, observing a significant enhancement in the orbital to spin moment ratio that is strongly localized to the interfacial region. Through the use of first-principles calculations, multivariate statistical analysis, and Electron Energy-Loss Spectroscopy (EELS), we explore the extent to which this enhancement can be attributed to emergent magnetism due to structural confinement at the interface. We conclude that this method has the potential to directly visualize spin and orbital moments at buried interfaces in magnetic systems with unprecedented spatial resolution.

  13. A Study on the Effects of Spatial Scale on Snow Process in Hyper-Resolution Hydrological Modelling over Mountainous Areas

    NASA Astrophysics Data System (ADS)

    Garousi Nejad, I.; He, S.; Tang, Q.; Ogden, F. L.; Steinke, R. C.; Frazier, N.; Tarboton, D. G.; Ohara, N.; Lin, H.

    2017-12-01

    Spatial scale is one of the main considerations in hydrological modeling of snowmelt in mountainous areas. The size of model elements controls the degree to which variability can be explicitly represented versus what needs to be parameterized using effective properties such as averages or other subgrid variability parameterizations that may degrade the quality of model simulations. For snowmelt modeling terrain parameters such as slope, aspect, vegetation and elevation play an important role in the timing and quantity of snowmelt that serves as an input to hydrologic runoff generation processes. In general, higher resolution enhances the accuracy of the simulation since fine meshes represent and preserve the spatial variability of atmospheric and surface characteristics better than coarse resolution. However, this increases computational cost and there may be a scale beyond which the model response does not improve due to diminishing sensitivity to variability and irreducible uncertainty associated with the spatial interpolation of inputs. This paper examines the influence of spatial resolution on the snowmelt process using simulations of and data from the Animas River watershed, an alpine mountainous area in Colorado, USA, using an unstructured distributed physically based hydrological model developed for a parallel computing environment, ADHydro. Five spatial resolutions (30 m, 100 m, 250 m, 500 m, and 1 km) were used to investigate the variations in hydrologic response. This study demonstrated the importance of choosing the appropriate spatial scale in the implementation of ADHydro to obtain a balance between representing spatial variability and the computational cost. According to the results, variation in the input variables and parameters due to using different spatial resolution resulted in changes in the obtained hydrological variables, especially snowmelt, both at the basin-scale and distributed across the model mesh.

  14. High quality high spatial resolution functional classification in low dose dynamic CT perfusion using singular value decomposition (SVD) and k-means clustering

    NASA Astrophysics Data System (ADS)

    Pisana, Francesco; Henzler, Thomas; Schönberg, Stefan; Klotz, Ernst; Schmidt, Bernhard; Kachelrieß, Marc

    2017-03-01

    Dynamic CT perfusion acquisitions are intrinsically high-dose examinations, due to repeated scanning. To keep radiation dose under control, relatively noisy images are acquired. Noise is then further enhanced during the extraction of functional parameters from the post-processing of the time attenuation curves of the voxels (TACs) and normally some smoothing filter needs to be employed to better visualize any perfusion abnormality, but sacrificing spatial resolution. In this study we propose a new method to detect perfusion abnormalities keeping both high spatial resolution and high CNR. To do this we first perform the singular value decomposition (SVD) of the original noisy spatial temporal data matrix to extract basis functions of the TACs. Then we iteratively cluster the voxels based on a smoothed version of the three most significant singular vectors. Finally, we create high spatial resolution 3D volumes where to each voxel is assigned a distance from the centroid of each cluster, showing how functionally similar each voxel is compared to the others. The method was tested on three noisy clinical datasets: one brain perfusion case with an occlusion in the left internal carotid, one healthy brain perfusion case, and one liver case with an enhancing lesion. Our method successfully detected all perfusion abnormalities with higher spatial precision when compared to the functional maps obtained with a commercially available software. We conclude this method might be employed to have a rapid qualitative indication of functional abnormalities in low dose dynamic CT perfusion datasets. The method seems to be very robust with respect to both spatial and temporal noise and does not require any special a priori assumption. While being more robust respect to noise and with higher spatial resolution and CNR when compared to the functional maps, our method is not quantitative and a potential usage in clinical routine could be as a second reader to assist in the maps evaluation, or to guide a dataset smoothing before the modeling part.

  15. Ultrabroadband infrared nanospectroscopic imaging

    PubMed Central

    Bechtel, Hans A.; Muller, Eric A.; Olmon, Robert L.; Martin, Michael C.; Raschke, Markus B.

    2014-01-01

    Characterizing and ultimately controlling the heterogeneity underlying biomolecular functions, quantum behavior of complex matter, photonic materials, or catalysis requires large-scale spectroscopic imaging with simultaneous specificity to structure, phase, and chemical composition at nanometer spatial resolution. However, as with any ultrahigh spatial resolution microscopy technique, the associated demand for an increase in both spatial and spectral bandwidth often leads to a decrease in desired sensitivity. We overcome this limitation in infrared vibrational scattering-scanning probe near-field optical microscopy using synchrotron midinfrared radiation. Tip-enhanced localized light–matter interaction is induced by low-noise, broadband, and spatially coherent synchrotron light of high spectral irradiance, and the near-field signal is sensitively detected using heterodyne interferometric amplification. We achieve sub-40-nm spatially resolved, molecular, and phonon vibrational spectroscopic imaging, with rapid spectral acquisition, spanning the full midinfrared (700–5,000 cm−1) with few cm−1 spectral resolution. We demonstrate the performance of synchrotron infrared nanospectroscopy on semiconductor, biomineral, and protein nanostructures, providing vibrational chemical imaging with subzeptomole sensitivity. PMID:24803431

  16. Ultra-long high-sensitivity Φ-OTDR for high spatial resolution intrusion detection of pipelines.

    PubMed

    Peng, Fei; Wu, Han; Jia, Xin-Hong; Rao, Yun-Jiang; Wang, Zi-Nan; Peng, Zheng-Pu

    2014-06-02

    An ultra-long phase-sensitive optical time domain reflectometry (Φ-OTDR) that can achieve high-sensitivity intrusion detection over 131.5km fiber with high spatial resolution of 8m is presented, which is the longest Φ-OTDR reported to date, to the best of our knowledge. It is found that the combination of distributed Raman amplification with heterodyne detection can extend the sensing distance and enhances the sensitivity substantially, leading to the realization of ultra-long Φ-OTDR with high sensitivity and spatial resolution. Furthermore, the feasibility of applying such an ultra-long Φ-OTDR to pipeline security monitoring is demonstrated and the features of intrusion signal can be extracted with improved SNR by using the wavelet detrending/denoising method proposed.

  17. Resolution Analysis of finite fault inversions: A back-projection approach.

    NASA Astrophysics Data System (ADS)

    Ji, C.; Shao, G.

    2007-12-01

    The resolution of inverted source models of large earthquakes is controlled by frequency contents of "coherent" (or "useful") seismic observations and their spatial distribution. But it is difficult to distinguish whether some features consistent during different inversions are really required by data or a consequence of "prior" information, such as velocity structures, fault geometry, model parameterizations. Here, we investigate the model spatial resolution by first back projecting and stacking the data at the source regions and then analyzing the spatial- temporal variations of the focusing regions, which arbitrarily defined as the regions with 90% of the peak focusing amplitude. Our preliminary results indicated 1) The spatial-temporal resolution at a particularly direction is controlled by the region of directivity parameter [pcos(θ)] within the seismic network, where p is the horizontal slowness from the hypocenter and θ is the difference between the station azimuth and this orientation. Therefore, the network aperture is more important than the number of stations. 2) Simple stacking method is a robust method to capture the asperities but the sizes of focusing regions are usually much larger than what data could resolve. By carefully weighting the data before the stacking could enhance the spatial resolution in a particular direction. 3) The results based on the teleseismic P waves of a local network usually surfers the trade-off between the source's spatial location and its rupture time. The resolution of the 2001 Kunlunshan earthquake and 2006 Kuril island earthquake will be investigated.

  18. Study of a high-resolution, 3D positioning cadmium zinc telluride detector for PET.

    PubMed

    Gu, Y; Matteson, J L; Skelton, R T; Deal, A C; Stephan, E A; Duttweiler, F; Gasaway, T M; Levin, C S

    2011-03-21

    This paper investigates the performance of 1 mm resolution cadmium zinc telluride (CZT) detectors for positron emission tomography (PET) capable of positioning the 3D coordinates of individual 511 keV photon interactions. The detectors comprise 40 mm × 40 mm × 5 mm monolithic CZT crystals that employ a novel cross-strip readout with interspersed steering electrodes to obtain high spatial and energy resolution. The study found a single anode FWHM energy resolution of 3.06 ± 0.39% at 511 keV throughout most of the detector volume. Improved resolution is expected with properly shielded front-end electronics. Measurements made using a collimated beam established the efficacy of the steering electrodes in facilitating enhanced charge collection across anodes, as well as a spatial resolution of 0.44 ± 0.07 mm in the direction orthogonal to the electrode planes. Finally, measurements based on coincidence electronic collimation yielded a point spread function with 0.78 ± 0.10 mm FWHM, demonstrating 1 mm spatial resolution capability transverse to the anodes-as expected from the 1 mm anode pitch. These findings indicate that the CZT-based detector concept has excellent performance and shows great promise for a high-resolution PET system.

  19. Evaluating the Impact of Spatial Resolution of Landsat Predictors on the Accuracy of Biomass Models for Large-area Estimation Across the Eastern USA

    NASA Astrophysics Data System (ADS)

    Deo, R. K.; Domke, G. M.; Russell, M.; Woodall, C. W.

    2017-12-01

    Landsat data have been widely used to support strategic forest inventory and management decisions despite the limited success of passive optical remote sensing for accurate estimation of aboveground biomass (AGB). The archive of publicly available Landsat data, available at 30-m spatial resolutions since 1984, has been a valuable resource for cost-effective large-area estimation of AGB to inform national requirements such as for the US national greenhouse gas inventory (NGHGI). In addition, other optical satellite data such as MODIS imagery of wider spatial coverage and higher temporal resolution are enriching the domain of spatial predictors for regional scale mapping of AGB. Because NGHGIs require national scale AGB information and there are tradeoffs in the prediction accuracy versus operational efficiency of Landsat, this study evaluated the impact of various resolutions of Landsat predictors on the accuracy of regional AGB models across three different sites in the eastern USA: Maine, Pennsylvania-New Jersey, and South Carolina. We used recent national forest inventory (NFI) data with numerous Landsat-derived predictors at ten different spatial resolutions ranging from 30 to 1000 m to understand the optimal spatial resolution of the optical data for enhanced spatial inventory of AGB for NGHGI reporting. Ten generic spatial models at different spatial resolutions were developed for all sites and large-area estimates were evaluated (i) at the county-level against the independent designed-based estimates via the US NFI Evalidator tool and (ii) within a large number of strips ( 1 km wide) predicted via LiDAR metrics at a high spatial resolution. The county-level estimates by the Evalidator and Landsat models were statistically equivalent and produced coefficients of determination (R2) above 0.85 that varied with sites and resolution of predictors. The mean and standard deviation of county-level estimates followed increasing and decreasing trends, respectively, with models of decreasing resolutions. The Landsat-based total AGB estimates within the strips against the total AGB obtained using LiDAR metrics did not differ significantly and were within ±15 Mg/ha for each of the sites. We conclude that the optical satellite data at resolutions up to 1000 m provide acceptable accuracy for the US' NGHGI.

  20. Improving the analysis of biogeochemical patterns associated with internal waves in the strait of Gibraltar using remote sensing images

    NASA Astrophysics Data System (ADS)

    Navarro, Gabriel; Vicent, Jorge; Caballero, Isabel; Gómez-Enri, Jesús; Morris, Edward P.; Sabater, Neus; Macías, Diego; Bolado-Penagos, Marina; Gomiz, Juan Jesús; Bruno, Miguel; Caldeira, Rui; Vázquez, Águeda

    2018-05-01

    High Amplitude Internal Waves (HAIWs) are physical processes observed in the Strait of Gibraltar (the narrow channel between the Atlantic Ocean and the Mediterranean Sea). These internal waves are generated over the Camarinal Sill (western side of the strait) during the tidal outflow (toward the Atlantic Ocean) when critical hydraulic conditions are established. HAIWs remain over the sill for up to 4 h until the outflow slackens, being then released (mostly) towards the Mediterranean Sea. These have been previously observed using Synthetic Aperture Radar (SAR), which captures variations in surface water roughness. However, in this work we use high resolution optical remote sensing, with the aim of examining the influence of HAIWs on biogeochemical processes. We used hyperspectral images from the Hyperspectral Imager for the Coastal Ocean (HICO) and high spatial resolution (10 m) images from the MultiSpectral Instrument (MSI) onboard the Sentinel-2A satellite. This work represents the first attempt to examine the relation between internal wave generation and the water constituents of the Camarinal Sill using hyperspectral and high spatial resolution remote sensing images. This enhanced spatial and spectral resolution revealed the detailed biogeochemical patterns associated with the internal waves and suggests local enhancements of productivity associated with internal waves trains.

  1. High spatial resolution fiber optical sensors for simultaneous temperature and chemical sensing for energy industries

    NASA Astrophysics Data System (ADS)

    Yan, Aidong; Huang, Sheng; Li, Shuo; Zaghloul, Mohamed; Ohodnicki, Paul; Buric, Michael; Chen, Kevin P.

    2017-05-01

    This paper demonstrates optical fibers as high-temperature sensor platforms. Through engineering and onfiber integration of functional metal oxide sensory materials, we report the development of an integrated sensor solution to perform temperature and chemical measurements for high-temperature energy applications. Using the Rayleigh optical frequency domain reflectometry (OFDR) distributed sensing scheme, the temperature and hydrogen concentration were measured along the fiber. To overcome the weak Rayleighbackscattering intensity exhibited by conventional optical fibers, an ultrafast laser was used to enhance the Rayleigh scattering by a direct laser writing method. Using the Rayleigh-enhanced fiber as sensor platform, both temperature and hydrogen reaction were monitored at high temperature up to 750°C with 4-mm spatial resolution.

  2. Split-spectrum processing technique for SNR enhancement of ultrasonic guided wave.

    PubMed

    Pedram, Seyed Kamran; Fateri, Sina; Gan, Lu; Haig, Alex; Thornicroft, Keith

    2018-02-01

    Ultrasonic guided wave (UGW) systems are broadly used in several branches of industry where the structural integrity is of concern. In those systems, signal interpretation can often be challenging due to the multi-modal and dispersive propagation of UGWs. This results in degradation of the signals in terms of signal-to-noise ratio (SNR) and spatial resolution. This paper employs the split-spectrum processing (SSP) technique in order to enhance the SNR and spatial resolution of UGW signals using the optimized filter bank parameters in real time scenario for pipe inspection. SSP technique has already been developed for other applications such as conventional ultrasonic testing for SNR enhancement. In this work, an investigation is provided to clarify the sensitivity of SSP performance to the filter bank parameter values for UGWs such as processing bandwidth, filter bandwidth, filter separation and a number of filters. As a result, the optimum values are estimated to significantly improve the SNR and spatial resolution of UGWs. The proposed method is synthetically and experimentally compared with conventional approaches employing different SSP recombination algorithms. The Polarity Thresholding (PT) and PT with Minimization (PTM) algorithms were found to be the best recombination algorithms. They substantially improved the SNR up to 36.9dB and 38.9dB respectively. The outcome of the work presented in this paper paves the way to enhance the reliability of UGW inspections. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Subpixel target detection and enhancement in hyperspectral images

    NASA Astrophysics Data System (ADS)

    Tiwari, K. C.; Arora, M.; Singh, D.

    2011-06-01

    Hyperspectral data due to its higher information content afforded by higher spectral resolution is increasingly being used for various remote sensing applications including information extraction at subpixel level. There is however usually a lack of matching fine spatial resolution data particularly for target detection applications. Thus, there always exists a tradeoff between the spectral and spatial resolutions due to considerations of type of application, its cost and other associated analytical and computational complexities. Typically whenever an object, either manmade, natural or any ground cover class (called target, endmembers, components or class) gets spectrally resolved but not spatially, mixed pixels in the image result. Thus, numerous manmade and/or natural disparate substances may occur inside such mixed pixels giving rise to mixed pixel classification or subpixel target detection problems. Various spectral unmixing models such as Linear Mixture Modeling (LMM) are in vogue to recover components of a mixed pixel. Spectral unmixing outputs both the endmember spectrum and their corresponding abundance fractions inside the pixel. It, however, does not provide spatial distribution of these abundance fractions within a pixel. This limits the applicability of hyperspectral data for subpixel target detection. In this paper, a new inverse Euclidean distance based super-resolution mapping method has been presented that achieves subpixel target detection in hyperspectral images by adjusting spatial distribution of abundance fraction within a pixel. Results obtained at different resolutions indicate that super-resolution mapping may effectively aid subpixel target detection.

  4. Resolution enhancement in coherent x-ray diffraction imaging by overcoming instrumental noise.

    PubMed

    Kim, Chan; Kim, Yoonhee; Song, Changyong; Kim, Sang Soo; Kim, Sunam; Kang, Hyon Chol; Hwu, Yeukuang; Tsuei, Ku-Ding; Liang, Keng San; Noh, Do Young

    2014-11-17

    We report that reference objects, strong scatterers neighboring weak phase objects, enhance the phase retrieval and spatial resolution in coherent x-ray diffraction imaging (CDI). A CDI experiment with Au nano-particles exhibited that the reference objects amplified the signal-to-noise ratio in the diffraction intensity at large diffraction angles, which significantly enhanced the image resolution. The interference between the diffracted x-ray from reference objects and a specimen also improved the retrieval of the phase of the diffraction signal. The enhancement was applied to image NiO nano-particles and a mitochondrion and confirmed in a simulation with a bacteria phantom. We expect that the proposed method will be of great help in imaging weakly scattering soft matters using coherent x-ray sources including x-ray free electron lasers.

  5. Eddy Fluxes and Sensitivity of the Water Cycle to Spatial Resolution in Idealized Regional Aquaplanet Model Simulations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hagos, Samson M.; Leung, Lai-Yung R.; Gustafson, William I.

    2014-02-28

    A multi-scale moisture budget analysis is used to identify the mechanisms responsible for the sensitivity of the water cycle to spatial resolution using idealized regional aquaplanet simulations. In the higher resolution simulations, moisture transport by eddies fluxes dry the boundary layer enhancing evaporation and precipitation. This effect of eddies, which is underestimated by the physics parameterizations in the low-resolution simulations, is found to be responsible for the sensitivity of the water cycle both directly, and through its upscale effect, on the mean circulation. Correlations among moisture transport by eddies at adjacent ranges of scales provides the potential for reducing thismore » sensitivity by representing the unresolved eddies by their marginally resolved counterparts.« less

  6. Systematic study and comparison of photonic nanojets produced by dielectric microparticles in 2D- and 3D-spatial configurations

    NASA Astrophysics Data System (ADS)

    Geints, Yu E.; Zemlyanov, A. A.; Minin, O. V.; Minin, I. V.

    2018-06-01

    We present the systematic study of key characteristics (field intensity enhancement, spatial extents) of the 2D- and 3D-photonic nanojets (PNJs) produced by geometrically-regular micron-sized dielectric particles illuminated by a plane laser wave. By means of the finite-difference time-domain calculations, we highlight the differences and similarities between PNJs in these two spatial configurations for curved- (sphere, circular cylinder) and rectangle-shaped scatterers (cube, square bar). Our findings can be useful, for example, for the design of particle-based high-resolution imaging because the spatial resolution by such systems might be further controlled by the optimization of refractive index contrast and geometrical shape of the particle-lens.

  7. Enhancing hyperspectral spatial resolution using multispectral image fusion: A wavelet approach

    NASA Astrophysics Data System (ADS)

    Jazaeri, Amin

    High spectral and spatial resolution images have a significant impact in remote sensing applications. Because both spatial and spectral resolutions of spaceborne sensors are fixed by design and it is not possible to further increase the spatial or spectral resolution, techniques such as image fusion must be applied to achieve such goals. This dissertation introduces the concept of wavelet fusion between hyperspectral and multispectral sensors in order to enhance the spectral and spatial resolution of a hyperspectral image. To test the robustness of this concept, images from Hyperion (hyperspectral sensor) and Advanced Land Imager (multispectral sensor) were first co-registered and then fused using different wavelet algorithms. A regression-based fusion algorithm was also implemented for comparison purposes. The results show that the fused images using a combined bi-linear wavelet-regression algorithm have less error than other methods when compared to the ground truth. In addition, a combined regression-wavelet algorithm shows more immunity to misalignment of the pixels due to the lack of proper registration. The quantitative measures of average mean square error show that the performance of wavelet-based methods degrades when the spatial resolution of hyperspectral images becomes eight times less than its corresponding multispectral image. Regardless of what method of fusion is utilized, the main challenge in image fusion is image registration, which is also a very time intensive process. Because the combined regression wavelet technique is computationally expensive, a hybrid technique based on regression and wavelet methods was also implemented to decrease computational overhead. However, the gain in faster computation was offset by the introduction of more error in the outcome. The secondary objective of this dissertation is to examine the feasibility and sensor requirements for image fusion for future NASA missions in order to be able to perform onboard image fusion. In this process, the main challenge of image registration was resolved by registering the input images using transformation matrices of previously acquired data. The composite image resulted from the fusion process remarkably matched the ground truth, indicating the possibility of real time onboard fusion processing.

  8. Single-Molecule Chemistry with Surface- and Tip-Enhanced Raman Spectroscopy.

    PubMed

    Zrimsek, Alyssa B; Chiang, Naihao; Mattei, Michael; Zaleski, Stephanie; McAnally, Michael O; Chapman, Craig T; Henry, Anne-Isabelle; Schatz, George C; Van Duyne, Richard P

    2017-06-14

    Single-molecule (SM) surface-enhanced Raman spectroscopy (SERS) and tip-enhanced Raman spectroscopy (TERS) have emerged as analytical techniques for characterizing molecular systems in nanoscale environments. SERS and TERS use plasmonically enhanced Raman scattering to characterize the chemical information on single molecules. Additionally, TERS can image single molecules with subnanometer spatial resolution. In this review, we cover the development and history of SERS and TERS, including the concept of SERS hot spots and the plasmonic nanostructures necessary for SM detection, the past and current methodologies for verifying SMSERS, and investigations into understanding the signal heterogeneities observed with SMSERS. Moving on to TERS, we cover tip fabrication and the physical origins of the subnanometer spatial resolution. Then, we highlight recent advances of SMSERS and TERS in fields such as electrochemistry, catalysis, and SM electronics, which all benefit from the vibrational characterization of single molecules. SMSERS and TERS provide new insights on molecular behavior that would otherwise be obscured in an ensemble-averaged measurement.

  9. Assessing resolution in live cell structured illumination microscopy

    NASA Astrophysics Data System (ADS)

    Pospíšil, Jakub; Fliegel, Karel; Klíma, Miloš

    2017-12-01

    Structured Illumination Microscopy (SIM) is a powerful super-resolution technique, which is able to enhance the resolution of optical microscope beyond the Abbe diffraction limit. In the last decade, numerous SIM methods that achieve the resolution of 100 nm in the lateral dimension have been developed. The SIM setups with new high-speed cameras and illumination pattern generators allow rapid acquisition of the live specimen. Therefore, SIM is widely used for investigation of the live structures in molecular and live cell biology. Quantitative evaluation of resolution enhancement in a real sample is essential to describe the efficiency of super-resolution microscopy technique. However, measuring the resolution of a live cell sample is a challenging task. Based on our experimental findings, the widely used Fourier ring correlation (FRC) method does not seem to be well suited for measuring the resolution of SIM live cell video sequences. Therefore, the resolution assessing methods based on Fourier spectrum analysis are often used. We introduce a measure based on circular average power spectral density (PSDca) estimated from a single SIM image (one video frame). PSDca describes the distribution of the power of a signal with respect to its spatial frequency. Spatial resolution corresponds to the cut-off frequency in Fourier space. In order to estimate the cut-off frequency from a noisy signal, we use a spectral subtraction method for noise suppression. In the future, this resolution assessment approach might prove useful also for single-molecule localization microscopy (SMLM) live cell imaging.

  10. Scaling effects on spring phenology detections from MODIS data at multiple spatial resolutions over the contiguous United States

    NASA Astrophysics Data System (ADS)

    Peng, Dailiang; Zhang, Xiaoyang; Zhang, Bing; Liu, Liangyun; Liu, Xinjie; Huete, Alfredo R.; Huang, Wenjiang; Wang, Siyuan; Luo, Shezhou; Zhang, Xiao; Zhang, Helin

    2017-10-01

    Land surface phenology (LSP) has been widely retrieved from satellite data at multiple spatial resolutions, but the spatial scaling effects on LSP detection are poorly understood. In this study, we collected enhanced vegetation index (EVI, 250 m) from collection 6 MOD13Q1 product over the contiguous United States (CONUS) in 2007 and 2008, and generated a set of multiple spatial resolution EVI data by resampling 250 m to 2 × 250 m and 3 × 250 m, 4 × 250 m, …, 35 × 250 m. These EVI time series were then used to detect the start of spring season (SOS) at various spatial resolutions. Further the SOS variation across scales was examined at each coarse resolution grid (35 × 250 m ≈ 8 km, refer to as reference grid) and ecoregion. Finally, the SOS scaling effects were associated with landscape fragment, proportion of primary land cover type, and spatial variability of seasonal greenness variation within each reference grid. The results revealed the influences of satellite spatial resolutions on SOS retrievals and the related impact factors. Specifically, SOS significantly varied lineally or logarithmically across scales although the relationship could be either positive or negative. The overall SOS values averaged from spatial resolutions between 250 m and 35 × 250 m at large ecosystem regions were generally similar with a difference less than 5 days, while the SOS values within the reference grid could differ greatly in some local areas. Moreover, the standard deviation of SOS across scales in the reference grid was less than 5 days in more than 70% of area over the CONUS, which was smaller in northeastern than in southern and western regions. The SOS scaling effect was significantly associated with heterogeneity of vegetation properties characterized using land landscape fragment, proportion of primary land cover type, and spatial variability of seasonal greenness variation, but the latter was the most important impact factor.

  11. Application of Geostatistical Simulation to Enhance Satellite Image Products

    NASA Technical Reports Server (NTRS)

    Hlavka, Christine A.; Dungan, Jennifer L.; Thirulanambi, Rajkumar; Roy, David

    2004-01-01

    With the deployment of Earth Observing System (EOS) satellites that provide daily, global imagery, there is increasing interest in defining the limitations of the data and derived products due to its coarse spatial resolution. Much of the detail, i.e. small fragments and notches in boundaries, is lost with coarse resolution imagery such as the EOS MODerate-Resolution Imaging Spectroradiometer (MODIS) data. Higher spatial resolution data such as the EOS Advanced Spaceborn Thermal Emission and Reflection Radiometer (ASTER), Landsat and airborne sensor imagery provide more detailed information but are less frequently available. There are, however, both theoretical and analytical evidence that burn scars and other fragmented types of land covers form self-similar or self-affine patterns, that is, patterns that look similar when viewed at widely differing spatial scales. Therefore small features of the patterns should be predictable, at least in a statistical sense, with knowledge about the large features. Recent developments in fractal modeling for characterizing the spatial distribution of undiscovered petroleum deposits are thus applicable to generating simulations of finer resolution satellite image products. We will present example EOS products, analysis to investigate self-similarity, and simulation results.

  12. In-flight edge response measurements for high-spatial-resolution remote sensing systems

    NASA Astrophysics Data System (ADS)

    Blonski, Slawomir; Pagnutti, Mary A.; Ryan, Robert; Zanoni, Vickie

    2002-09-01

    In-flight measurements of spatial resolution were conducted as part of the NASA Scientific Data Purchase Verification and Validation process. Characterization included remote sensing image products with ground sample distance of 1 meter or less, such as those acquired with the panchromatic imager onboard the IKONOS satellite and the airborne ADAR System 5500 multispectral instrument. Final image products were used to evaluate the effects of both the image acquisition system and image post-processing. Spatial resolution was characterized by full width at half maximum of an edge-response-derived line spread function. The edge responses were analyzed using the tilted-edge technique that overcomes the spatial sampling limitations of the digital imaging systems. As an enhancement to existing algorithms, the slope of the edge response and the orientation of the edge target were determined by a single computational process. Adjacent black and white square panels, either painted on a flat surface or deployed as tarps, formed the ground-based edge targets used in the tests. Orientation of the deployable tarps was optimized beforehand, based on simulations of the imaging system. The effects of such factors as acquisition geometry, temporal variability, Modulation Transfer Function compensation, and ground sample distance on spatial resolution were investigated.

  13. Super-resolution mapping using multi-viewing CHRIS/PROBA data

    NASA Astrophysics Data System (ADS)

    Dwivedi, Manish; Kumar, Vinay

    2016-04-01

    High-spatial resolution Remote Sensing (RS) data provides detailed information which ensures high-definition visual image analysis of earth surface features. These data sets also support improved information extraction capabilities at a fine scale. In order to improve the spatial resolution of coarser resolution RS data, the Super Resolution Reconstruction (SRR) technique has become widely acknowledged which focused on multi-angular image sequences. In this study multi-angle CHRIS/PROBA data of Kutch area is used for SR image reconstruction to enhance the spatial resolution from 18 m to 6m in the hope to obtain a better land cover classification. Various SR approaches like Projection onto Convex Sets (POCS), Robust, Iterative Back Projection (IBP), Non-Uniform Interpolation and Structure-Adaptive Normalized Convolution (SANC) chosen for this study. Subjective assessment through visual interpretation shows substantial improvement in land cover details. Quantitative measures including peak signal to noise ratio and structural similarity are used for the evaluation of the image quality. It was observed that SANC SR technique using Vandewalle algorithm for the low resolution image registration outperformed the other techniques. After that SVM based classifier is used for the classification of SRR and data resampled to 6m spatial resolution using bi-cubic interpolation. A comparative analysis is carried out between classified data of bicubic interpolated and SR derived images of CHRIS/PROBA and SR derived classified data have shown a significant improvement of 10-12% in the overall accuracy. The results demonstrated that SR methods is able to improve spatial detail of multi-angle images as well as the classification accuracy.

  14. Future VIIRS enhancements for the integrated polar-orbiting environmental satellite system

    NASA Astrophysics Data System (ADS)

    Puschell, Jeffery J.; Silny, John; Cook, Lacy; Kim, Eugene

    2010-08-01

    The Visible/Infrared Imager Radiometer Suite (VIIRS) is the next-generation imaging spectroradiometer for the future operational polar-orbiting environmental satellite system. A successful Flight Unit 1 has been delivered and integrated onto the NPP spacecraft. The flexible VIIRS architecture can be adapted and enhanced to respond to a wide range of requirements and to incorporate new technology as it becomes available. This paper reports on recent design studies to evaluate building a MW-VLWIR dispersive hyperspectral module with active cooling into the existing VIIRS architecture. Performance of a two-grating VIIRS hyperspectral module was studied across a broad trade space defined primarily by spatial sampling, spectral range, spectral sampling interval, along-track field of view and integration time. The hyperspectral module studied here provides contiguous coverage across 3.9 - 15.5 μm with a spectral sampling interval of 10 nm or better, thereby extending VIIRS spectral range to the shortwave side of the 15.5 μm CO2 band and encompassing the 6.7 μm H2O band. Spatial sampling occurs at VIIRS I-band (~0.4 km at nadir) spatial resolution with aggregation to M-band (~0.8 km) and larger pixel sizes to improve sensitivity. Radiometric sensitivity (NEdT) at a spatial resolution of ~4 km is ~0.1 K or better for a 250 K scene across a wavelength range of 4.5 μm to 15.5 μm. The large number of high spectral and spatial resolution FOVs in this instrument improves chances for retrievals of information on the physical state and composition of the atmosphere all the way to the surface in cloudy regions relative to current systems. Spectral aggregation of spatial resolution measurements to MODIS and VIIRS multispectral bands would continue legacy measurements with better sensitivity in nearly all bands. Additional work is needed to optimize spatial sampling, spectral range and spectral sampling approaches for the hyperspectral module and to further refine this powerful imager concept.

  15. Adaptive windowing in contrast-enhanced intravascular ultrasound imaging

    PubMed Central

    Lindsey, Brooks D.; Martin, K. Heath; Jiang, Xiaoning; Dayton, Paul A.

    2016-01-01

    Intravascular ultrasound (IVUS) is one of the most commonly-used interventional imaging techniques and has seen recent innovations which attempt to characterize the risk posed by atherosclerotic plaques. One such development is the use of microbubble contrast agents to image vasa vasorum, fine vessels which supply oxygen and nutrients to the walls of coronary arteries and typically have diameters less than 200 µm. The degree of vasa vasorum neovascularization within plaques is positively correlated with plaque vulnerability. Having recently presented a prototype dual-frequency transducer for contrast agent-specific intravascular imaging, here we describe signal processing approaches based on minimum variance (MV) beamforming and the phase coherence factor (PCF) for improving the spatial resolution and contrast-to-tissue ratio (CTR) in IVUS imaging. These approaches are examined through simulations, phantom studies, ex vivo studies in porcine arteries, and in vivo studies in chicken embryos. In phantom studies, PCF processing improved CTR by a mean of 4.2 dB, while combined MV and PCF processing improved spatial resolution by 41.7%. Improvements of 2.2 dB in CTR and 37.2% in resolution were observed in vivo. Applying these processing strategies can enhance image quality in conventional B-mode IVUS or in contrast-enhanced IVUS, where signal-to-noise ratio is relatively low and resolution is at a premium. PMID:27161022

  16. Generating daily high spatial land surface temperatures by combining ASTER and MODIS land surface temperature products for environmental process monitoring.

    PubMed

    Wu, Mingquan; Li, Hua; Huang, Wenjiang; Niu, Zheng; Wang, Changyao

    2015-08-01

    There is a shortage of daily high spatial land surface temperature (LST) data for use in high spatial and temporal resolution environmental process monitoring. To address this shortage, this work used the Spatial and Temporal Adaptive Reflectance Fusion Model (STARFM), Enhanced Spatial and Temporal Adaptive Reflectance Fusion Model (ESTARFM), and the Spatial and Temporal Data Fusion Approach (STDFA) to estimate high spatial and temporal resolution LST by combining Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) LST and Moderate Resolution Imaging Spectroradiometer (MODIS) LST products. The actual ASTER LST products were used to evaluate the precision of the combined LST images using the correlation analysis method. This method was tested and validated in study areas located in Gansu Province, China. The results show that all the models can generate daily synthetic LST image with a high correlation coefficient (r) of 0.92 between the synthetic image and the actual ASTER LST observations. The ESTARFM has the best performance, followed by the STDFA and the STARFM. Those models had better performance in desert areas than in cropland. The STDFA had better noise immunity than the other two models.

  17. Compressed Sensing for Resolution Enhancement of Hyperpolarized 13C Flyback 3D-MRSI

    PubMed Central

    Hu, Simon; Lustig, Michael; Chen, Albert P.; Crane, Jason; Kerr, Adam; Kelley, Douglas A.C.; Hurd, Ralph; Kurhanewicz, John; Nelson, Sarah J.; Pauly, John M.; Vigneron, Daniel B.

    2008-01-01

    High polarization of nuclear spins in liquid state through dynamic nuclear polarization has enabled the direct monitoring of 13C metabolites in vivo at very high signal to noise, allowing for rapid assessment of tissue metabolism. The abundant SNR afforded by this hyperpolarization technique makes high resolution 13C 3D-MRSI feasible. However, the number of phase encodes that can be fit into the short acquisition time for hyperpolarized imaging limits spatial coverage and resolution. To take advantage of the high SNR available from hyperpolarization, we have applied compressed sensing to achieve a factor of 2 enhancement in spatial resolution without increasing acquisition time or decreasing coverage. In this paper, the design and testing of compressed sensing suited for a flyback 13C 3D-MRSI sequence are presented. The key to this design was the undersampling of spectral k-space using a novel blipped scheme, thus taking advantage of the considerable sparsity in typical hyperpolarized 13C spectra. Phantom tests validated the accuracy of the compressed sensing approach and initial mouse experiments demonstrated in vivo feasibility. PMID:18367420

  18. Distributed fiber optic vibration sensor with enhanced response bandwidth and high signal-to-noise ratio

    NASA Astrophysics Data System (ADS)

    Chen, Dian; Liu, Qingwen; Fan, Xinyu; He, Zuyuan

    2017-04-01

    A novel distributed fiber-optic vibration sensor (DVS) is proposed based on multi-pulse time-gated digital optical frequency domain reflectometry (TGD-OFDR), which can solve both the trade-off between the maximum measurable distance and the spatial resolution, and the one between the measurement distance and the vibration response bandwidth. A 21-kHz vibration is detected experimentally over 10-kilometer-long fiber, with a signal-to-noise ratio approaching 25 dB and a spatial resolution of 10 m.

  19. Landsat multispectral sharpening using a sensor system model and panchromatic image

    USGS Publications Warehouse

    Lemeshewsky, G.P.; ,

    2003-01-01

    The thematic mapper (TM) sensor aboard Landsats 4, 5 and enhanced TM plus (ETM+) on Landsat 7 collect imagery at 30-m sample distance in six spectral bands. New with ETM+ is a 15-m panchromatic (P) band. With image sharpening techniques, this higher resolution P data, or as an alternative, the 10-m (or 5-m) P data of the SPOT satellite, can increase the spatial resolution of the multispectral (MS) data. Sharpening requires that the lower resolution MS image be coregistered and resampled to the P data before high spatial frequency information is transferred to the MS data. For visual interpretation and machine classification tasks, it is important that the sharpened data preserve the spectral characteristics of the original low resolution data. A technique was developed for sharpening (in this case, 3:1 spatial resolution enhancement) visible spectral band data, based on a model of the sensor system point spread function (PSF) in order to maintain spectral fidelity. It combines high-pass (HP) filter sharpening methods with iterative image restoration to reduce degradations caused by sensor-system-induced blurring and resembling. Also there is a spectral fidelity requirement: sharpened MS when filtered by the modeled degradations should reproduce the low resolution source MS. Quantitative evaluation of sharpening performance was made by using simulated low resolution data generated from digital color-IR aerial photography. In comparison to the HP-filter-based sharpening method, results for the technique in this paper with simulated data show improved spectral fidelity. Preliminary results with TM 30-m visible band data sharpened with simulated 10-m panchromatic data are promising but require further study.

  20. Cone-beam micro computed tomography dedicated to the breast.

    PubMed

    Sarno, Antonio; Mettivier, Giovanni; Di Lillo, Francesca; Cesarelli, Mario; Bifulco, Paolo; Russo, Paolo

    2016-12-01

    We developed a scanner for micro computed tomography dedicated to the breast (BµCT) with a high resolution flat-panel detector and a microfocus X-ray tube. We evaluated the system spatial resolution via the 3D modulation transfer function (MTF). In addition to conventional absorption-based X-ray imaging, such a prototype showed capabilities for propagation-based phase-contrast and related edge enhancement effects in 3D imaging. The system limiting spatial resolution is 6.2mm -1 (MTF at 10%) in the vertical direction and 3.8mm -1 in the radial direction, values which compare favorably with the spatial resolution reached by mini focus breast CT scanners of other groups. The BµCT scanner was able to detect both microcalcification clusters and masses in an anthropomorphic breast phantom at a dose comparable to that of two-view mammography. The use of a breast holder is proposed in order to have 1-2min long scan times without breast motion artifacts. Copyright © 2016 IPEM. Published by Elsevier Ltd. All rights reserved.

  1. Built-Up Area Detection from High-Resolution Satellite Images Using Multi-Scale Wavelet Transform and Local Spatial Statistics

    NASA Astrophysics Data System (ADS)

    Chen, Y.; Zhang, Y.; Gao, J.; Yuan, Y.; Lv, Z.

    2018-04-01

    Recently, built-up area detection from high-resolution satellite images (HRSI) has attracted increasing attention because HRSI can provide more detailed object information. In this paper, multi-resolution wavelet transform and local spatial autocorrelation statistic are introduced to model the spatial patterns of built-up areas. First, the input image is decomposed into high- and low-frequency subbands by wavelet transform at three levels. Then the high-frequency detail information in three directions (horizontal, vertical and diagonal) are extracted followed by a maximization operation to integrate the information in all directions. Afterward, a cross-scale operation is implemented to fuse different levels of information. Finally, local spatial autocorrelation statistic is introduced to enhance the saliency of built-up features and an adaptive threshold algorithm is used to achieve the detection of built-up areas. Experiments are conducted on ZY-3 and Quickbird panchromatic satellite images, and the results show that the proposed method is very effective for built-up area detection.

  2. Study of a high-resolution, 3-D positioning cadmium zinc telluride detector for PET

    PubMed Central

    Gu, Y; Matteson, J L; Skelton, R T; Deal, A C; Stephan, E A; Duttweiler, F; Gasaway, T M; Levin, C S

    2011-01-01

    This paper investigates the performance of 1 mm resolution Cadmium Zinc Telluride (CZT) detectors for positron emission tomography (PET) capable of positioning the 3-D coordinates of individual 511 keV photon interactions. The detectors comprise 40 mm × 40 mm × 5 mm monolithic CZT crystals that employ a novel cross-strip readout with interspersed steering electrodes to obtain high spatial and energy resolution. The study found a single anode FWHM energy resolution of 3.06±0.39% at 511 keV throughout most the detector volume. Improved resolution is expected with properly shielded front-end electronics. Measurements made using a collimated beam established the efficacy of the steering electrodes in facilitating enhanced charge collection across anodes, as well as a spatial resolution of 0.44±0.07 mm in the direction orthogonal to the electrode planes. Finally, measurements based on coincidence electronic collimation yielded a point spread function with 0.78±0.10 mm FWHM, demonstrating 1 mm spatial resolution capability transverse to the anodes – as expected from the 1 mm anode pitch. These findings indicate that the CZT-based detector concept has excellent performance and shows great promise for a high-resolution PET system. PMID:21335649

  3. Appalachian Mountains

    Atmospheric Science Data Center

    2014-05-15

    ... Radiance Ellipsoid Product. MISR uses this enhanced sensitivity along with the angular variation in signal to monitor particulate ... of MISR's unique capability of providing moderately high spatial resolution, calibrated imagery at very oblique angles. Gradations ...

  4. Spatially resolved measurement of singlet delta oxygen by radar resonance-enhanced multiphoton ionization.

    PubMed

    Wu, Yue; Zhang, Zhili; Ombrello, Timothy M

    2013-07-01

    Coherent microwave Rayleigh scattering (Radar) from resonance-enhanced multiphoton ionization (REMPI) was demonstrated to directly and nonintrusively measure singlet delta oxygen, O(2)(a(1)Δ(g)), with high spatial resolution. Two different approaches, photodissociation of ozone and microwave discharge plasma in an argon and oxygen flow, were utilized for O(2)(a(1)Δ(g)) generation. The d(1)Π(g)←a(1)Δ(g) (3-0) and d(1)Π(g)←a(1)Δ(g) (1-0) bands of O(2)(a(1)Δ(g)) were detected by Radar REMPI for two different flow conditions. Quantitative absorption measurements using sensitive off-axis integrated cavity output spectroscopy (ICOS) was used simultaneously to evaluate the accuracy and sensitivity of the Radar REMPI technique. The detection limit of Radar REMPI was found to be comparable to the ICOS technique with a detection threshold of approximately 10(14) molecules/cm(3) but with a spatial resolution that was 8 orders of magnitude smaller than the ICOS technique.

  5. Automated brain tumor segmentation using spatial accuracy-weighted hidden Markov Random Field.

    PubMed

    Nie, Jingxin; Xue, Zhong; Liu, Tianming; Young, Geoffrey S; Setayesh, Kian; Guo, Lei; Wong, Stephen T C

    2009-09-01

    A variety of algorithms have been proposed for brain tumor segmentation from multi-channel sequences, however, most of them require isotropic or pseudo-isotropic resolution of the MR images. Although co-registration and interpolation of low-resolution sequences, such as T2-weighted images, onto the space of the high-resolution image, such as T1-weighted image, can be performed prior to the segmentation, the results are usually limited by partial volume effects due to interpolation of low-resolution images. To improve the quality of tumor segmentation in clinical applications where low-resolution sequences are commonly used together with high-resolution images, we propose the algorithm based on Spatial accuracy-weighted Hidden Markov random field and Expectation maximization (SHE) approach for both automated tumor and enhanced-tumor segmentation. SHE incorporates the spatial interpolation accuracy of low-resolution images into the optimization procedure of the Hidden Markov Random Field (HMRF) to segment tumor using multi-channel MR images with different resolutions, e.g., high-resolution T1-weighted and low-resolution T2-weighted images. In experiments, we evaluated this algorithm using a set of simulated multi-channel brain MR images with known ground-truth tissue segmentation and also applied it to a dataset of MR images obtained during clinical trials of brain tumor chemotherapy. The results show that more accurate tumor segmentation results can be obtained by comparing with conventional multi-channel segmentation algorithms.

  6. Example-based super-resolution for single-image analysis from the Chang'e-1 Mission

    NASA Astrophysics Data System (ADS)

    Wu, Fan-Lu; Wang, Xiang-Jun

    2016-11-01

    Due to the low spatial resolution of images taken from the Chang'e-1 (CE-1) orbiter, the details of the lunar surface are blurred and lost. Considering the limited spatial resolution of image data obtained by a CCD camera on CE-1, an example-based super-resolution (SR) algorithm is employed to obtain high-resolution (HR) images. SR reconstruction is important for the application of image data to increase the resolution of images. In this article, a novel example-based algorithm is proposed to implement SR reconstruction by single-image analysis, and the computational cost is reduced compared to other example-based SR methods. The results show that this method can enhance the resolution of images using SR and recover detailed information about the lunar surface. Thus it can be used for surveying HR terrain and geological features. Moreover, the algorithm is significant for the HR processing of remotely sensed images obtained by other imaging systems.

  7. Estimating Soil Moisture at High Spatial Resolution with Three Radiometric Satellite Products: A Study from a South-Eastern Australian Catchment

    NASA Astrophysics Data System (ADS)

    Senanayake, I. P.; Yeo, I. Y.; Tangdamrongsub, N.; Willgoose, G. R.; Hancock, G. R.; Wells, T.; Fang, B.; Lakshmi, V.

    2017-12-01

    Long-term soil moisture datasets at high spatial resolution are important in agricultural, hydrological, and climatic applications. The soil moisture estimates can be achieved using satellite remote sensing observations. However, the satellite soil moisture data are typically available at coarse spatial resolutions ( several tens of km), therefore require further downscaling. Different satellite soil moisture products have to be conjointly employed in developing a consistent time-series of high resolution soil moisture, while the discrepancies amongst different satellite retrievals need to be resolved. This study aims to downscale three different satellite soil moisture products, the Soil Moisture and Ocean Salinity (SMOS, 25 km), the Soil Moisture Active Passive (SMAP, 36 km) and the SMAP-Enhanced (9 km), and to conduct an inter-comparison of the downscaled results. The downscaling approach is developed based on the relationship between the diurnal temperature difference and the daily mean soil moisture content. The approach is applied to two sub-catchments (Krui and Merriwa River) of the Goulburn River catchment in the Upper Hunter region (NSW, Australia) to estimate soil moisture at 1 km resolution for 2015. The three coarse spatial resolution soil moisture products and their downscaled results will be validated with the in-situ observations obtained from the Scaling and Assimilation of Soil Moisture and Streamflow (SASMAS) network. The spatial and temporal patterns of the downscaled results will also be analysed. This study will provide the necessary insights for data selection and bias corrections to maintain the consistency of a long-term high resolution soil moisture dataset. The results will assist in developing a time-series of high resolution soil moisture data over the south-eastern Australia.

  8. View-sharing PROPELLER with pixel-based optimal blade selection: application on dynamic contrast-enhanced imaging.

    PubMed

    Chuang, Tzu-Chao; Huang, Hsuan-Hung; Chang, Hing-Chiu; Wu, Ming-Ting

    2014-06-01

    To achieve better spatial and temporal resolution of dynamic contrast-enhanced MR imaging, the concept of k-space data sharing, or view sharing, can be implemented for PROPELLER acquisition. As found in other view-sharing methods, the loss of high-resolution dynamics is possible for view-sharing PROPELLER (VS-Prop) due to the temporal smoothing effect. The degradation can be more severe when a narrow blade with less phase encoding steps is chosen in the acquisition for higher frame rate. In this study, an iterative algorithm termed pixel-based optimal blade selection (POBS) is proposed to allow spatially dependent selection of the rotating blades, to generate high-resolution dynamic images with minimal reconstruction artifacts. In the reconstruction of VS-Prop, the central k-space which dominates the image contrast is only provided by the target blade with the peripheral k-space contributed by a minimal number of consecutive rotating blades. To reduce the reconstruction artifacts, the set of neighboring blades exhibiting the closest image contrast with the target blade is picked by POBS algorithm. Numerical simulations and phantom experiments were conducted in this study to investigate the dynamic response and spatial profiles of images generated using our proposed method. In addition, dynamic contrast-enhanced cardiovascular imaging of healthy subjects was performed to demonstrate the feasibility and advantages. The simulation results show that POBS VS-Prop can provide timely dynamic response to rapid signal change, especially for a small region of interest or with the use of narrow blades. The POBS algorithm also demonstrates its capability to capture nonsimultaneous signal changes over the entire FOV. In addition, both phantom and in vivo experiments show that the temporal smoothing effect can be avoided by means of POBS, leading to higher wash-in slope of contrast enhancement after the bolus injection. With the satisfactory reconstruction quality provided by the POBS algorithm, VS-Prop acquisition technique may find useful clinical applications in DCE MR imaging studies where both spatial and temporal resolutions play important roles.

  9. Land use change detection based on multi-date imagery from different satellite sensor systems

    NASA Technical Reports Server (NTRS)

    Stow, Douglas A.; Collins, Doretta; Mckinsey, David

    1990-01-01

    An empirical study is conducted to assess the accuracy of land use change detection using satellite image data acquired ten years apart by sensors with differing spatial resolutions. The primary goals of the investigation were to (1) compare standard change detection methods applied to image data of varying spatial resolution, (2) assess whether to transform the raster grid of the higher resolution image data to that of the lower resolution raster grid or vice versa in the registration process, (3) determine if Landsat/Thermatic Mapper or SPOT/High Resolution Visible multispectral data provide more accurate detection of land use changes when registered to historical Landsat/MSS data. It is concluded that image ratioing of multisensor, multidate satellite data produced higher change detection accuracies than did principal components analysis, and that it is useful as a land use change enhancement method.

  10. Fusion of spectral and panchromatic images using false color mapping and wavelet integrated approach

    NASA Astrophysics Data System (ADS)

    Zhao, Yongqiang; Pan, Quan; Zhang, Hongcai

    2006-01-01

    With the development of sensory technology, new image sensors have been introduced that provide a greater range of information to users. But as the power limitation of radiation, there will always be some trade-off between spatial and spectral resolution in the image captured by specific sensors. Images with high spatial resolution can locate objects with high accuracy, whereas images with high spectral resolution can be used to identify the materials. Many applications in remote sensing require fusing low-resolution imaging spectral images with panchromatic images to identify materials at high resolution in clutter. A pixel-based false color mapping and wavelet transform integrated fusion algorithm is presented in this paper, the resulting images have a higher information content than each of the original images and retain sensor-specific image information. The simulation results show that this algorithm can enhance the visibility of certain details and preserve the difference of different materials.

  11. Building the Forest Inventory and Analysis Tree-Ring Data set

    Treesearch

    Robert J. DeRose; John D. Shaw; James N. Long

    2017-01-01

    The Interior West Forest Inventory and Analysis (IW-FIA) program measures forestland conditions at great extent with relatively high spatial resolution, including the collection of tree-ring data. We describe the development of an unprecedented spatial tree-ring data set for the IW-FIA that enhances the baseline plot data by incorporating ring-width increment measured...

  12. Sci-Fri PM: Radiation Therapy, Planning, Imaging, and Special Techniques - 01: On the use of proton radiography to reduce beam range uncertainties and improve patient positioning accuracy in proton therapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Collins-Fekete, Charles-Antoine; Beaulieu, Luc; Se

    2016-08-15

    To present two related developments of proton radiography (pRad) to minimize range uncertainty in proton therapy. The first combines a pRad with an X-ray CT to produce a patient-specific relative stopping power (RSP) map. The second aims to improve the pRad spatial resolution for accurate registration prior to the first. The enhanced-pRad can also be used in a novel proton-CT reconstruction algorithm. Monte Carlo pRad were computed from three phantoms; the Gammex, the Catphan and an anthropomorphic head. An optimized cubic-spline estimator derives the most likely path. The length crossed by the protons voxel-by-voxel was calculated by combining their estimatedmore » paths with the CT. The difference between the theoretical (length×RSP) and measured energy loss was minimized through a least squares optimization (LSO) algorithm yielding the RSP map. To increase pRad spatial resolution for registration with the CT, the phantom was discretized into voxels columns. The average column RSP was optimized to maximize the proton energy loss likelihood (MLE). Simulations showed precise RSP (<0.75%) for Gammex materials except low-density lung (<1.2%). For the head, accurate RSP were obtained (µ=−0.10%1.5σ=1.12%) and the range precision was improved (ΔR80 of −0.20±0.35%). Spatial resolution was increased in pRad (2.75 to 6.71 lp/cm) and pCT from MLE-enhanced pRad (2.83 to 5.86 lp/cm). The LSO decreases the range uncertainty (R80σ<1.0%) while the MLE-enhanced pRad spatial resolution (+244%) and is a great candidate for pCT reconstruction.« less

  13. Spatial, Temporal and Spectral Satellite Image Fusion via Sparse Representation

    NASA Astrophysics Data System (ADS)

    Song, Huihui

    Remote sensing provides good measurements for monitoring and further analyzing the climate change, dynamics of ecosystem, and human activities in global or regional scales. Over the past two decades, the number of launched satellite sensors has been increasing with the development of aerospace technologies and the growing requirements on remote sensing data in a vast amount of application fields. However, a key technological challenge confronting these sensors is that they tradeoff between spatial resolution and other properties, including temporal resolution, spectral resolution, swath width, etc., due to the limitations of hardware technology and budget constraints. To increase the spatial resolution of data with other good properties, one possible cost-effective solution is to explore data integration methods that can fuse multi-resolution data from multiple sensors, thereby enhancing the application capabilities of available remote sensing data. In this thesis, we propose to fuse the spatial resolution with temporal resolution and spectral resolution, respectively, based on sparse representation theory. Taking the study case of Landsat ETM+ (with spatial resolution of 30m and temporal resolution of 16 days) and MODIS (with spatial resolution of 250m ~ 1km and daily temporal resolution) reflectance, we propose two spatial-temporal fusion methods to combine the fine spatial information of Landsat image and the daily temporal resolution of MODIS image. Motivated by that the images from these two sensors are comparable on corresponding bands, we propose to link their spatial information on available Landsat- MODIS image pair (captured on prior date) and then predict the Landsat image from the MODIS counterpart on prediction date. To well-learn the spatial details from the prior images, we use a redundant dictionary to extract the basic representation atoms for both Landsat and MODIS images based on sparse representation. Under the scenario of two prior Landsat-MODIS image pairs, we build the corresponding relationship between the difference images of MODIS and ETM+ by training a low- and high-resolution dictionary pair from the given prior image pairs. In the second scenario, i.e., only one Landsat- MODIS image pair being available, we directly correlate MODIS and ETM+ data through an image degradation model. Then, the fusion stage is achieved by super-resolving the MODIS image combining the high-pass modulation in a two-layer fusion framework. Remarkably, the proposed spatial-temporal fusion methods form a unified framework for blending remote sensing images with phenology change or land-cover-type change. Based on the proposed spatial-temporal fusion models, we propose to monitor the land use/land cover changes in Shenzhen, China. As a fast-growing city, Shenzhen faces the problem of detecting the rapid changes for both rational city planning and sustainable development. However, the cloudy and rainy weather in region Shenzhen located makes the capturing circle of high-quality satellite images longer than their normal revisit periods. Spatial-temporal fusion methods are capable to tackle this problem by improving the spatial resolution of images with coarse spatial resolution but frequent temporal coverage, thereby making the detection of rapid changes possible. On two Landsat-MODIS datasets with annual and monthly changes, respectively, we apply the proposed spatial-temporal fusion methods to the task of multiple change detection. Afterward, we propose a novel spatial and spectral fusion method for satellite multispectral and hyperspectral (or high-spectral) images based on dictionary-pair learning and sparse non-negative matrix factorization. By combining the spectral information from hyperspectral image, which is characterized by low spatial resolution but high spectral resolution and abbreviated as LSHS, and the spatial information from multispectral image, which is featured by high spatial resolution but low spectral resolution and abbreviated as HSLS, this method aims to generate the fused data with both high spatial and high spectral resolutions. Motivated by the observation that each hyperspectral pixel can be represented by a linear combination of a few endmembers, this method first extracts the spectral bases of LSHS and HSLS images by making full use of the rich spectral information in LSHS data. The spectral bases of these two categories data then formulate a dictionary-pair due to their correspondence in representing each pixel spectra of LSHS data and HSLS data, respectively. Subsequently, the LSHS image is spatially unmixed by representing the HSLS image with respect to the corresponding learned dictionary to derive its representation coefficients. Combining the spectral bases of LSHS data and the representation coefficients of HSLS data, we finally derive the fused data characterized by the spectral resolution of LSHS data and the spatial resolution of HSLS data.

  14. A method for generating high resolution satellite image time series

    NASA Astrophysics Data System (ADS)

    Guo, Tao

    2014-10-01

    There is an increasing demand for satellite remote sensing data with both high spatial and temporal resolution in many applications. But it still is a challenge to simultaneously improve spatial resolution and temporal frequency due to the technical limits of current satellite observation systems. To this end, much R&D efforts have been ongoing for years and lead to some successes roughly in two aspects, one includes super resolution, pan-sharpen etc. methods which can effectively enhance the spatial resolution and generate good visual effects, but hardly preserve spectral signatures and result in inadequate analytical value, on the other hand, time interpolation is a straight forward method to increase temporal frequency, however it increase little informative contents in fact. In this paper we presented a novel method to simulate high resolution time series data by combing low resolution time series data and a very small number of high resolution data only. Our method starts with a pair of high and low resolution data set, and then a spatial registration is done by introducing LDA model to map high and low resolution pixels correspondingly. Afterwards, temporal change information is captured through a comparison of low resolution time series data, and then projected onto the high resolution data plane and assigned to each high resolution pixel according to the predefined temporal change patterns of each type of ground objects. Finally the simulated high resolution data is generated. A preliminary experiment shows that our method can simulate a high resolution data with a reasonable accuracy. The contribution of our method is to enable timely monitoring of temporal changes through analysis of time sequence of low resolution images only, and usage of costly high resolution data can be reduces as much as possible, and it presents a highly effective way to build up an economically operational monitoring solution for agriculture, forest, land use investigation, environment and etc. applications.

  15. Soil moisture downscaling using a simple thermal based proxy

    NASA Astrophysics Data System (ADS)

    Peng, Jian; Loew, Alexander; Niesel, Jonathan

    2016-04-01

    Microwave remote sensing has been largely applied to retrieve soil moisture (SM) from active and passive sensors. The obvious advantage of microwave sensor is that SM can be obtained regardless of atmospheric conditions. However, existing global SM products only provide observations at coarse spatial resolutions, which often hamper their applications in regional hydrological studies. Therefore, various downscaling methods have been proposed to enhance the spatial resolution of satellite soil moisture products. The aim of this study is to investigate the validity and robustness of a simple Vegetation Temperature Condition Index (VTCI) downscaling scheme over different climates and regions. Both polar orbiting (MODIS) and geostationary (MSG SEVIRI) satellite data are used to improve the spatial resolution of the European Space Agency's Water Cycle Multi-mission Observation Strategy and Climate Change Initiative (ESA CCI) soil moisture, which is a merged product based on both active and passive microwave observations. The results from direct validation against soil moisture in-situ measurements, spatial pattern comparison, as well as seasonal and land use analyses show that the downscaling method can significantly improve the spatial details of CCI soil moisture while maintain the accuracy of CCI soil moisture. The application of the scheme with different satellite platforms and over different regions further demonstrate the robustness and effectiveness of the proposed method. Therefore, the VTCI downscaling method has the potential to facilitate relevant hydrological applications that require high spatial and temporal resolution soil moisture.

  16. Analyzing Snowpack Metrics Over Large Spatial Extents Using Calibrated, Enhanced-Resolution Brightness Temperature Data and Long Short Term Memory Artificial Neural Networks

    NASA Astrophysics Data System (ADS)

    Norris, W.; J Q Farmer, C.

    2017-12-01

    Snow water equivalence (SWE) is a difficult metric to measure accurately over large spatial extents; snow-tell sites are too localized, and traditional remotely sensed brightness temperature data is at too coarse of a resolution to capture variation. The new Calibrated Enhanced-Resolution Brightness Temperature (CETB) data from the National Snow and Ice Data Center (NSIDC) offers remotely sensed brightness temperature data at an enhanced resolution of 3.125 km versus the original 25 km, which allows for large spatial extents to be analyzed with reduced uncertainty compared to the 25km product. While the 25km brightness temperature data has proved useful in past research — one group found decreasing trends in SWE outweighed increasing trends three to one in North America; other researchers used the data to incorporate winter conditions, like snow cover, into ecological zoning criterion — with the new 3.125 km data, it is possible to derive more accurate metrics for SWE, since we have far more spatial variability in measurements. Even with higher resolution data, using the 37 - 19 GHz frequencies to estimate SWE distorts the data during times of melt onset and accumulation onset. Past researchers employed statistical splines, while other successful attempts utilized non-parametric curve fitting to smooth out spikes distorting metrics. In this work, rather than using legacy curve fitting techniques, a Long Short Term Memory (LSTM) Artificial Neural Network (ANN) was trained to perform curve fitting on the data. LSTM ANN have shown great promise in modeling time series data, and with almost 40 years of data available — 14,235 days — there is plenty of training data for the ANN. LSTM's are ideal for this type of time series analysis because they allow important trends to persist for long periods of time, but ignore short term fluctuations; since LSTM's have poor mid- to short-term memory, they are ideal for smoothing out the large spikes generated in the melt and accumulation onset seasons, while still capturing the overall trends in the data.

  17. Enhancing resolution in coherent x-ray diffraction imaging.

    PubMed

    Noh, Do Young; Kim, Chan; Kim, Yoonhee; Song, Changyong

    2016-12-14

    Achieving a resolution near 1 nm is a critical issue in coherent x-ray diffraction imaging (CDI) for applications in materials and biology. Albeit with various advantages of CDI based on synchrotrons and newly developed x-ray free electron lasers, its applications would be limited without improving resolution well below 10 nm. Here, we review the issues and efforts in improving CDI resolution including various methods for resolution determination. Enhancing diffraction signal at large diffraction angles, with the aid of interference between neighboring strong scatterers or templates, is reviewed and discussed in terms of increasing signal-to-noise ratio. In addition, we discuss errors in image reconstruction algorithms-caused by the discreteness of the Fourier transformations involved-which degrade the spatial resolution, and suggest ways to correct them. We expect this review to be useful for applications of CDI in imaging weakly scattering soft matters using coherent x-ray sources including x-ray free electron lasers.

  18. Regional forest land cover characterisation using medium spatial resolution satellite data

    USGS Publications Warehouse

    Huang, Chengquan; Homer, Collin G.; Yang, Limin; Wulder, Michael A.; Franklin, Steven E.

    2003-01-01

    Increasing demands on forest resources require comprehensive, consistent and up-to-date information on those resources at spatial scales appropriate for management decision-making and for scientific analysis. While such information can be derived using coarse spatial resolution satellite data (e.g. Tucker et al. 1984; Zhu and Evans 1994; Cihlar et al. 1996; Cihlar et al., Chapter 12), many regional applications require more spatial and thematic details than can be derived by using coarse resolution imagery. High spatial resolution satellite data such as IKONOS and Quick Bird images (Aplin et al. 1997), though usable for deriving detailed forest information (Culvenor, Chapter 9), are currently not feasible for wall-to-wall regional applications because of extremely high data cost, huge data volume, and lack of contiguous coverage over large areas. Forest studies over large areas have often been accomplished using data acquired by intermediate spatial resolution sensor systems, including the Multi-Spectral Scanner (MSS), Thematic Mapper (TM) and the Enhanced Thematic Mapper Plus (ETM+) of Landsat, the High Resolution Visible (HRV) of the Systeme Pour l'Observation de la Terre (SPOT), and the Linear Image Self-Scanner (LISS) of the Indian Remote Sensing satellite. These sensor systems are more appropriate for regional applications because they can routinely produce spatially contiguous data over large areas at relatively low cost, and can be used to derive a host of forest attributes (e.g. Cohen et al. 1995; Kimes et al. 1999; Cohen et al. 2001; Huang et al. 2001; Sugumaran 2001). Of the above intermediate spatial resolution satellites, Landsat is perhaps the most widely used in various types of land remote sensing applications, in part because it has provided more extensive spatial and temporal coverage of the globe than any other intermediate resolution satellite. Spatially contiguous Landsat data have been developed for many regions of the globe (e.g. Lunetta and Sturdevant 1993; Fuller et al. 1994b; Skole et al. 1997), and a circa 1990 Landsat image data set covering the entire land area of the globe has also been developed recently (Jones and Smith 2001). An acquisition strategy aimed at acquiring at least one cloud free image per year for the entire land area of the globe has been initiated for Landsat-7 (Arvidson et al. 2001). This will probably ensure the continued dominance of Landsat in the near future.

  19. Vegetation Coverage and Impervious Surface Area Estimated Based on the Estarfm Model and Remote Sensing Monitoring

    NASA Astrophysics Data System (ADS)

    Hu, Rongming; Wang, Shu; Guo, Jiao; Guo, Liankun

    2018-04-01

    Impervious surface area and vegetation coverage are important biophysical indicators of urban surface features which can be derived from medium-resolution images. However, remote sensing data obtained by a single sensor are easily affected by many factors such as weather conditions, and the spatial and temporal resolution can not meet the needs for soil erosion estimation. Therefore, the integrated multi-source remote sensing data are needed to carry out high spatio-temporal resolution vegetation coverage estimation. Two spatial and temporal vegetation coverage data and impervious data were obtained from MODIS and Landsat 8 remote sensing images. Based on the Enhanced Spatial and Temporal Adaptive Reflectance Fusion Model (ESTARFM), the vegetation coverage data of two scales were fused and the data of vegetation coverage fusion (ESTARFM FVC) and impervious layer with high spatiotemporal resolution (30 m, 8 day) were obtained. On this basis, the spatial variability of the seepage-free surface and the vegetation cover landscape in the study area was measured by means of statistics and spatial autocorrelation analysis. The results showed that: 1) ESTARFM FVC and impermeable surface have higher accuracy and can characterize the characteristics of the biophysical components covered by the earth's surface; 2) The average impervious surface proportion and the spatial configuration of each area are different, which are affected by natural conditions and urbanization. In the urban area of Xi'an, which has typical characteristics of spontaneous urbanization, landscapes are fragmented and have less spatial dependence.

  20. Enhanced PET resolution by combining pinhole collimation and coincidence detection

    NASA Astrophysics Data System (ADS)

    DiFilippo, Frank P.

    2015-10-01

    Spatial resolution of clinical PET scanners is limited by detector design and photon non-colinearity. Although dedicated small animal PET scanners using specialized high-resolution detectors have been developed, enhancing the spatial resolution of clinical PET scanners is of interest as a more available alternative. Multi-pinhole 511 keV SPECT is capable of high spatial resolution but requires heavily shielded collimators to avoid significant background counts. A practical approach with clinical PET detectors is to combine multi-pinhole collimation with coincidence detection. In this new hybrid modality, there are three locations associated with each event, namely those of the two detected photons and the pinhole aperture. These three locations over-determine the line of response and provide redundant information that is superior to coincidence detection or pinhole collimation alone. Multi-pinhole collimation provides high resolution and avoids non-colinearity error but is subject to collimator penetration and artifacts from overlapping projections. However the coincidence information, though at lower resolution, is valuable for determining whether the photon passed near a pinhole within the cone acceptance angle and for identifying through which pinhole the photon passed. This information allows most photons penetrating through the collimator to be rejected and avoids overlapping projections. With much improved event rejection, a collimator with minimal shielding may be used, and a lightweight add-on collimator for high resolution imaging is feasible for use with a clinical PET scanner. Monte Carlo simulations were performed of a 18F hot rods phantom and a 54-pinhole unfocused whole-body mouse collimator with a clinical PET scanner. Based on coincidence information and pinhole geometry, events were accepted or rejected, and pinhole-specific crystal-map projections were generated. Tomographic images then were reconstructed using a conventional pinhole SPECT algorithm. Hot rods of 1.4 mm diameter were resolved easily in a simulated phantom. System sensitivity was 0.09% for a simulated 70-mm line source corresponding to the NEMA NU-4 mouse phantom. Higher resolution is expected with further optimization of pinhole design, and higher sensitivity is expected with a focused and denser pinhole configuration. The simulations demonstrate high spatial resolution and feasibility of small animal imaging with an add-on multi-pinhole collimator for a clinical PET scanner. Further work is needed to develop geometric calibration and quantitative data corrections and, eventually, to construct a prototype device and produce images with physical phantoms.

  1. Nano-Optics for Chemical and Materials Characterization

    NASA Astrophysics Data System (ADS)

    Beversluis, Michael; Stranick, Stephan

    2007-03-01

    Light microscopy can provide non-destructive, real-time, three-dimensional imaging with chemically-specific contrast, but diffraction frequently limits the resolution to roughly 200 nm. Recently, structured illumination techniques have allowed fluorescence imaging to reach 50 nm resolution [1]. Since these fluorescence techniques were developed for use in microbiology, a key challenge is to take the resolution-enhancing features and apply them to contrast mechanisms like vibrational spectroscopy (e.g., Raman and CARS microscopy) that provide morphological and chemically specific imaging.. We are developing a new hybrid technique that combines the resolution enhancement of structured illumination microscopy with scanning techniques that can record hyperspectral images with 100 nm spatial resolution. We will show such superresolving images of semiconductor nanostructures and discuss the advantages and requirements for this technique. Referenence: 1. M. G. L. Gustafsson, P. Natl. Acad. Sci. USA 102, 13081-13086 (2005).

  2. Single-Molecule and Superresolution Imaging in Live Bacteria Cells

    PubMed Central

    Biteen, Julie S.; Moerner, W.E.

    2010-01-01

    Single-molecule imaging enables biophysical measurements devoid of ensemble averaging, gives enhanced spatial resolution beyond the diffraction limit, and permits superresolution reconstructions. Here, single-molecule and superresolution imaging are applied to the study of proteins in live Caulobacter crescentus cells to illustrate the power of these methods in bacterial imaging. Based on these techniques, the diffusion coefficient and dynamics of the histidine protein kinase PleC, the localization behavior of the polar protein PopZ, and the treadmilling behavior and protein superstructure of the structural protein MreB are investigated with sub-40-nm spatial resolution, all in live cells. PMID:20300204

  3. Correlation Plenoptic Imaging.

    PubMed

    D'Angelo, Milena; Pepe, Francesco V; Garuccio, Augusto; Scarcelli, Giuliano

    2016-06-03

    Plenoptic imaging is a promising optical modality that simultaneously captures the location and the propagation direction of light in order to enable three-dimensional imaging in a single shot. However, in standard plenoptic imaging systems, the maximum spatial and angular resolutions are fundamentally linked; thereby, the maximum achievable depth of field is inversely proportional to the spatial resolution. We propose to take advantage of the second-order correlation properties of light to overcome this fundamental limitation. In this Letter, we demonstrate that the correlation in both momentum and position of chaotic light leads to the enhanced refocusing power of correlation plenoptic imaging with respect to standard plenoptic imaging.

  4. Correlation Plenoptic Imaging

    NASA Astrophysics Data System (ADS)

    D'Angelo, Milena; Pepe, Francesco V.; Garuccio, Augusto; Scarcelli, Giuliano

    2016-06-01

    Plenoptic imaging is a promising optical modality that simultaneously captures the location and the propagation direction of light in order to enable three-dimensional imaging in a single shot. However, in standard plenoptic imaging systems, the maximum spatial and angular resolutions are fundamentally linked; thereby, the maximum achievable depth of field is inversely proportional to the spatial resolution. We propose to take advantage of the second-order correlation properties of light to overcome this fundamental limitation. In this Letter, we demonstrate that the correlation in both momentum and position of chaotic light leads to the enhanced refocusing power of correlation plenoptic imaging with respect to standard plenoptic imaging.

  5. Segmentation of arterial vessel wall motion to sub-pixel resolution using M-mode ultrasound.

    PubMed

    Fancourt, Craig; Azer, Karim; Ramcharan, Sharmilee L; Bunzel, Michelle; Cambell, Barry R; Sachs, Jeffrey R; Walker, Matthew

    2008-01-01

    We describe a method for segmenting arterial vessel wall motion to sub-pixel resolution, using the returns from M-mode ultrasound. The technique involves measuring the spatial offset between all pairs of scans from their cross-correlation, converting the spatial offsets to relative wall motion through a global optimization, and finally translating from relative to absolute wall motion by interpolation over the M-mode image. The resulting detailed wall distension waveform has the potential to enhance existing vascular biomarkers, such as strain and compliance, as well as enable new ones.

  6. Quantum enhanced superresolution microscopy (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Oron, Dan; Tenne, Ron; Israel, Yonatan; Silberberg, Yaron

    2017-02-01

    Far-field optical microscopy beyond the Abbe diffraction limit, making use of nonlinear excitation (e.g. STED), or temporal fluctuations in fluorescence (PALM, STORM, SOFI) is already a reality. In contrast, overcoming the diffraction limit using non-classical properties of light is very difficult to achieve due to the fragility of quantum states of light. Here, we experimentally demonstrate superresolution microscopy based on quantum properties of light naturally emitted by fluorophores used as markers in fluorescence microscopy. Our approach is based on photon antibunching, the tendency of fluorophores to emit photons one by one rather than in bursts. Although a distinctively quantum phenomenon, antibunching is readily observed in most common fluorophores even at room temperature. This nonclassical resource can be utilized directly to enhance the imaging resolution, since the non-classical far-field intensity correlations induced by antibunching carry high spatial frequency information on the spatial distribution of emitters. Detecting photon statistics simultaneously in the entire field of view, we were able to detect non-classical correlations of the second and third order, and reconstructed images with resolution significantly beyond the diffraction limit. Alternatively, we demonstrate the utilization of antibunching for augmenting the capabilities of localization-based superresolution imaging in the presence of multiple emitters, using a novel detector comprised of an array of single photon detectors connected to a densely packed fiber bundle. These features allow us to enhance the spatial and temporal resolution with which multiple emitters can be imaged compared with other techniques that rely on CCD cameras.

  7. Improving spatial and spectral resolution of TCV Thomson scattering

    NASA Astrophysics Data System (ADS)

    Hawke, J.; Andrebe, Y.; Bertizzolo, R.; Blanchard, P.; Chavan, R.; Decker, J.; Duval, B.; Lavanchy, P.; Llobet, X.; Marlétaz, B.; Marmillod, P.; Pochon, G.; Toussaint, M.

    2017-12-01

    The recently completed MST2 upgrade to the Thomson scattering (TS) system on TCV (Tokamak à Configuration Variable) at the Swiss Plasma Center aims to provide an enhanced spatial and spectral resolution while maintaining the high level of diagnostic flexibility for the study of TCV plasmas. The MST2 (Medium Sized Tokamak) is a work program within the Eurofusion ITER physics department, aimed at exploiting Europe's medium sized tokamak programs for a better understanding of ITER physics. This upgrade to the TCV Thomson scattering system involved the installation of 40 new compact 5-channel spectrometers and modifications to the diagnostics fiber optic design. The complete redesign of the fiber optic backplane incorporates fewer larger diameter fibers, allowing for a higher resolution in both the core and edge of TCV plasmas along the laser line, with a slight decrease in the signal to noise ratio of Thomson measurements. The 40 new spectrometers added to the system are designed to cover the full range of temperatures expected in TCV, able to measure electron temperatures (Te) with high precision between (6 eV and 20 keV) . The design of these compact spectrometers stems originally from the design utilized in the MAST (Mega Amp Spherical Tokamak) TS system located in Oxfordshire, United Kingdom. This design was implemented on TCV with an overall layout of optical fibers and spectrometers to achieve an overall increase in the spatial resolution, specifically a resolution of approximately 1% of the minor radius within the plasma pedestal region. These spectrometers also enhance the diagnostic spectral resolution, especially within the plasma edge, due to the low Te measurement capabilities. These additional spectrometers allow for a much greater diagnostic flexibility, allowing for quality full Thomson profiles in 75% of TCV plasma configurations.

  8. Science with High Spatial Resolution Far-Infrared Data

    NASA Technical Reports Server (NTRS)

    Terebey, Susan (Editor); Mazzarella, Joseph M. (Editor)

    1994-01-01

    The goal of this workshop was to discuss new science and techniques relevant to high spatial resolution processing of far-infrared data, with particular focus on high resolution processing of IRAS data. Users of the maximum correlation method, maximum entropy, and other resolution enhancement algorithms applicable to far-infrared data gathered at the Infrared Processing and Analysis Center (IPAC) for two days in June 1993 to compare techniques and discuss new results. During a special session on the third day, interested astronomers were introduced to IRAS HIRES processing, which is IPAC's implementation of the maximum correlation method to the IRAS data. Topics discussed during the workshop included: (1) image reconstruction; (2) random noise; (3) imagery; (4) interacting galaxies; (5) spiral galaxies; (6) galactic dust and elliptical galaxies; (7) star formation in Seyfert galaxies; (8) wavelet analysis; and (9) supernova remnants.

  9. Blind identification of full-field vibration modes of output-only structures from uniformly-sampled, possibly temporally-aliased (sub-Nyquist), video measurements

    NASA Astrophysics Data System (ADS)

    Yang, Yongchao; Dorn, Charles; Mancini, Tyler; Talken, Zachary; Nagarajaiah, Satish; Kenyon, Garrett; Farrar, Charles; Mascareñas, David

    2017-03-01

    Enhancing the spatial and temporal resolution of vibration measurements and modal analysis could significantly benefit dynamic modelling, analysis, and health monitoring of structures. For example, spatially high-density mode shapes are critical for accurate vibration-based damage localization. In experimental or operational modal analysis, higher (frequency) modes, which may be outside the frequency range of the measurement, contain local structural features that can improve damage localization as well as the construction and updating of the modal-based dynamic model of the structure. In general, the resolution of vibration measurements can be increased by enhanced hardware. Traditional vibration measurement sensors such as accelerometers have high-frequency sampling capacity; however, they are discrete point-wise sensors only providing sparse, low spatial sensing resolution measurements, while dense deployment to achieve high spatial resolution is expensive and results in the mass-loading effect and modification of structure's surface. Non-contact measurement methods such as scanning laser vibrometers provide high spatial and temporal resolution sensing capacity; however, they make measurements sequentially that requires considerable acquisition time. As an alternative non-contact method, digital video cameras are relatively low-cost, agile, and provide high spatial resolution, simultaneous, measurements. Combined with vision based algorithms (e.g., image correlation or template matching, optical flow, etc.), video camera based measurements have been successfully used for experimental and operational vibration measurement and subsequent modal analysis. However, the sampling frequency of most affordable digital cameras is limited to 30-60 Hz, while high-speed cameras for higher frequency vibration measurements are extremely costly. This work develops a computational algorithm capable of performing vibration measurement at a uniform sampling frequency lower than what is required by the Shannon-Nyquist sampling theorem for output-only modal analysis. In particular, the spatio-temporal uncoupling property of the modal expansion of structural vibration responses enables a direct modal decoupling of the temporally-aliased vibration measurements by existing output-only modal analysis methods, yielding (full-field) mode shapes estimation directly. Then the signal aliasing properties in modal analysis is exploited to estimate the modal frequencies and damping ratios. The proposed method is validated by laboratory experiments where output-only modal identification is conducted on temporally-aliased acceleration responses and particularly the temporally-aliased video measurements of bench-scale structures, including a three-story building structure and a cantilever beam.

  10. Improved Technology To Prevent Nuclear Proliferation And Counter Nuclear Terrorism

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Richardson, J; Yuldashev, B; Labov, S

    2006-06-12

    As the world moves into the 21st century, the possibility of greater reliance on nuclear energy will impose additional technical requirements to prevent proliferation. In addition to proliferation resistant reactors, a careful examination of the various possible fuel cycles from cradle to grave will provide additional technical and nonproliferation challenges in the areas of conversion, enrichment, transportation, recycling and waste disposal. Radiation detection technology and information management have a prominent role in any future global regime for nonproliferation. As nuclear energy and hence nuclear materials become an increasingly global phenomenon, using local technologies and capabilities facilitate incorporation of enhanced monitoringmore » and detection on the regional level. Radiation detection technologies are an important tool in the prevention of proliferation and countering radiological/nuclear terrorism. A variety of new developments have enabled enhanced performance in terms of energy resolution, spatial resolution, passive detection, predictive modeling and simulation, active interrogation, and ease of operation and deployment in the field. For example, various gamma ray imaging approaches are being explored to combine spatial resolution with background suppression in order to enhance sensitivity many-fold at reasonable standoff distances and acquisition times. New materials and approaches are being developed in order to provide adequate energy resolution in field use without the necessity for liquid nitrogen. Different detection algorithms enable fissile materials to be distinguished from other radioisotopes.« less

  11. Adaptive windowing in contrast-enhanced intravascular ultrasound imaging.

    PubMed

    Lindsey, Brooks D; Martin, K Heath; Jiang, Xiaoning; Dayton, Paul A

    2016-08-01

    Intravascular ultrasound (IVUS) is one of the most commonly-used interventional imaging techniques and has seen recent innovations which attempt to characterize the risk posed by atherosclerotic plaques. One such development is the use of microbubble contrast agents to image vasa vasorum, fine vessels which supply oxygen and nutrients to the walls of coronary arteries and typically have diameters less than 200μm. The degree of vasa vasorum neovascularization within plaques is positively correlated with plaque vulnerability. Having recently presented a prototype dual-frequency transducer for contrast agent-specific intravascular imaging, here we describe signal processing approaches based on minimum variance (MV) beamforming and the phase coherence factor (PCF) for improving the spatial resolution and contrast-to-tissue ratio (CTR) in IVUS imaging. These approaches are examined through simulations, phantom studies, ex vivo studies in porcine arteries, and in vivo studies in chicken embryos. In phantom studies, PCF processing improved CTR by a mean of 4.2dB, while combined MV and PCF processing improved spatial resolution by 41.7%. Improvements of 2.2dB in CTR and 37.2% in resolution were observed in vivo. Applying these processing strategies can enhance image quality in conventional B-mode IVUS or in contrast-enhanced IVUS, where signal-to-noise ratio is relatively low and resolution is at a premium. Copyright © 2016 Elsevier B.V. All rights reserved.

  12. Recent Developments in PET Instrumentation

    PubMed Central

    Peng, Hao; Levin, Craig S.

    2013-01-01

    Positron emission tomography (PET) is used in the clinic and in vivo small animal research to study molecular processes associated with diseases such as cancer, heart disease, and neurological disorders, and to guide the discovery and development of new treatments. This paper reviews current challenges of advancing PET technology and some of newly developed PET detectors and systems. The paper focuses on four aspects of PET instrumentation: high photon detection sensitivity; improved spatial resolution; depth-of-interaction (DOI) resolution and time-of-flight (TOF). Improved system geometry, novel non-scintillator based detectors, and tapered scintillation crystal arrays are able to enhance the photon detection sensitivity of a PET system. Several challenges for achieving high resolution with standard scintillator-based PET detectors are discussed. Novel detectors with 3-D positioning capability have great potential to be deployed in PET for achieving spatial resolution better than 1 mm, such as cadmium-zinc-telluride (CZT) and position-sensitive avalanche photodiodes (PSAPDs). DOI capability enables a PET system to mitigate parallax error and achieve uniform spatial resolution across the field-of-view (FOV). Six common DOI designs, as well as advantages and limitations of each design, are discussed. The availability of fast scintillation crystals such as LaBr3, and the silicon photomultiplier (SiPM) greatly advances TOF-PET development. Recent instrumentation and initial results of clinical trials are briefly presented. If successful, these technology advances, together with new probe molecules, will substantially enhance the molecular sensitivity of PET and thus increase its role in preclinical and clinical research as well as evaluating and managing disease in the clinic. PMID:20497121

  13. Multitemporal MODIS-EVI relationships with precipitation and temperature at the Santa Rita Experimental Range

    Treesearch

    Jorry Z. U. Kaurivi; Alfredo R. Huete; Kamel Didan

    2003-01-01

    The Moderate Resolution Imaging Spectroradiometer (MODIS) provides temporal enhanced vegetation index (EVI) data at 250, 500, and 1,000 m spatial resolutions that can be compared to daily, weekly, monthly, and annual weather parameters. A study was conducted at the grassland site (less than 10 percent velvet mesquite [Prosopis juliflora, var. velutina]) and the...

  14. Spatial and radiometric characterization of multi-spectrum satellite images through multi-fractal analysis

    NASA Astrophysics Data System (ADS)

    Alonso, Carmelo; Tarquis, Ana M.; Zúñiga, Ignacio; Benito, Rosa M.

    2017-03-01

    Several studies have shown that vegetation indexes can be used to estimate root zone soil moisture. Earth surface images, obtained by high-resolution satellites, presently give a lot of information on these indexes, based on the data of several wavelengths. Because of the potential capacity for systematic observations at various scales, remote sensing technology extends the possible data archives from the present time to several decades back. Because of this advantage, enormous efforts have been made by researchers and application specialists to delineate vegetation indexes from local scale to global scale by applying remote sensing imagery. In this work, four band images have been considered, which are involved in these vegetation indexes, and were taken by satellites Ikonos-2 and Landsat-7 of the same geographic location, to study the effect of both spatial (pixel size) and radiometric (number of bits coding the image) resolution on these wavelength bands as well as two vegetation indexes: the Normalized Difference Vegetation Index (NDVI) and the Enhanced Vegetation Index (EVI). In order to do so, a multi-fractal analysis of these multi-spectral images was applied in each of these bands and the two indexes derived. The results showed that spatial resolution has a similar scaling effect in the four bands, but radiometric resolution has a larger influence in blue and green bands than in red and near-infrared bands. The NDVI showed a higher sensitivity to the radiometric resolution than EVI. Both were equally affected by the spatial resolution. From both factors, the spatial resolution has a major impact in the multi-fractal spectrum for all the bands and the vegetation indexes. This information should be taken in to account when vegetation indexes based on different satellite sensors are obtained.

  15. High-Spatial- and High-Temporal-Resolution Dynamic Contrast-enhanced MR Breast Imaging with Sweep Imaging with Fourier Transformation: A Pilot Study

    PubMed Central

    Benson, John C.; Idiyatullin, Djaudat; Snyder, Angela L.; Snyder, Carl J.; Hutter, Diane; Everson, Lenore I.; Eberly, Lynn E.; Nelson, Michael T.; Garwood, Michael

    2015-01-01

    Purpose To report the results of sweep imaging with Fourier transformation (SWIFT) magnetic resonance (MR) imaging for diagnostic breast imaging. Materials and Methods Informed consent was obtained from all participants under one of two institutional review board–approved, HIPAA-compliant protocols. Twelve female patients (age range, 19–54 years; mean age, 41.2 years) and eight normal control subjects (age range, 22–56 years; mean age, 43.2 years) enrolled and completed the study from January 28, 2011, to March 5, 2013. Patients had previous lesions that were Breast Imaging Reporting and Data System 4 and 5 based on mammography and/or ultrasonographic imaging. Contrast-enhanced SWIFT imaging was completed by using a 4-T research MR imaging system. Noncontrast studies were completed in the normal control subjects. One of two sized single-breast SWIFT-compatible transceiver coils was used for nine patients and five controls. Three patients and five control subjects used a SWIFT-compatible dual breast coil. Temporal resolution was 5.9–7.5 seconds. Spatial resolution was 1.00 mm isotropic, with later examinations at 0.67 mm isotropic, and dual breast at 1.00 mm or 0.75 mm isotropic resolution. Results Two nonblinded breast radiologists reported SWIFT image findings of normal breast tissue, benign fibroadenomas (six of six lesions), and malignant lesions (10 of 12 lesions) concordant with other imaging modalities and pathologic reports. Two lesions in two patients were not visualized because of coil field of view. The images yielded by SWIFT showed the presence and extent of known breast lesions. Conclusion The SWIFT technique could become an important addition to breast imaging modalities because it provides high spatial resolution at all points during the dynamic contrast-enhanced examination. © RSNA, 2014 PMID:25247405

  16. High-resolution gadolinium-enhanced 3D MRA of the infrapopliteal arteries. Lessons for improving bolus-chase peripheral MRA.

    PubMed

    Hood, Maureen N; Ho, Vincent B; Foo, Thomas K F; Marcos, Hani B; Hess, Sandra L; Choyke, Peter L

    2002-09-01

    Peripheral magnetic resonance angiography (MRA) is growing in use. However, methods of performing peripheral MRA vary widely and continue to be optimized, especially for improvement in illustration of infrapopliteal arteries. The main purpose of this project was to identify imaging factors that can improve arterial visualization in the lower leg using bolus chase peripheral MRA. Eighteen healthy adults were imaged on a 1.5T MR scanner. The calf was imaged using conventional three-station bolus chase three-dimensional (3D) MRA, two dimensional (2D) time-of-flight (TOF) MRA and single-station Gadolinium (Gd)-enhanced 3D MRA. Observer comparisons of vessel visualization, signal to noise ratios (SNR), contrast to noise ratios (CNR) and spatial resolution comparisons were performed. Arterial SNR and CNR were similar for all three techniques. However, arterial visualization was dramatically improved on dedicated, arterial-phase Gd-enhanced 3D MRA compared with the multi-station bolus chase MRA and 2D TOF MRA. This improvement was related to optimization of Gd-enhanced 3D MRA parameters (fast injection rate of 2 mL/sec, high spatial resolution imaging, the use of dedicated phased array coils, elliptical centric k-space sampling and accurate arterial phase timing for image acquisition). The visualization of the infrapopliteal arteries can be substantially improved in bolus chase peripheral MRA if voxel size, contrast delivery, and central k-space data acquisition for arterial enhancement are optimized. Improvements in peripheral MRA should be directed at these parameters.

  17. Enhancing the performance of the light field microscope using wavefront coding

    PubMed Central

    Cohen, Noy; Yang, Samuel; Andalman, Aaron; Broxton, Michael; Grosenick, Logan; Deisseroth, Karl; Horowitz, Mark; Levoy, Marc

    2014-01-01

    Light field microscopy has been proposed as a new high-speed volumetric computational imaging method that enables reconstruction of 3-D volumes from captured projections of the 4-D light field. Recently, a detailed physical optics model of the light field microscope has been derived, which led to the development of a deconvolution algorithm that reconstructs 3-D volumes with high spatial resolution. However, the spatial resolution of the reconstructions has been shown to be non-uniform across depth, with some z planes showing high resolution and others, particularly at the center of the imaged volume, showing very low resolution. In this paper, we enhance the performance of the light field microscope using wavefront coding techniques. By including phase masks in the optical path of the microscope we are able to address this non-uniform resolution limitation. We have also found that superior control over the performance of the light field microscope can be achieved by using two phase masks rather than one, placed at the objective’s back focal plane and at the microscope’s native image plane. We present an extended optical model for our wavefront coded light field microscope and develop a performance metric based on Fisher information, which we use to choose adequate phase masks parameters. We validate our approach using both simulated data and experimental resolution measurements of a USAF 1951 resolution target; and demonstrate the utility for biological applications with in vivo volumetric calcium imaging of larval zebrafish brain. PMID:25322056

  18. Enhancing the performance of the light field microscope using wavefront coding.

    PubMed

    Cohen, Noy; Yang, Samuel; Andalman, Aaron; Broxton, Michael; Grosenick, Logan; Deisseroth, Karl; Horowitz, Mark; Levoy, Marc

    2014-10-06

    Light field microscopy has been proposed as a new high-speed volumetric computational imaging method that enables reconstruction of 3-D volumes from captured projections of the 4-D light field. Recently, a detailed physical optics model of the light field microscope has been derived, which led to the development of a deconvolution algorithm that reconstructs 3-D volumes with high spatial resolution. However, the spatial resolution of the reconstructions has been shown to be non-uniform across depth, with some z planes showing high resolution and others, particularly at the center of the imaged volume, showing very low resolution. In this paper, we enhance the performance of the light field microscope using wavefront coding techniques. By including phase masks in the optical path of the microscope we are able to address this non-uniform resolution limitation. We have also found that superior control over the performance of the light field microscope can be achieved by using two phase masks rather than one, placed at the objective's back focal plane and at the microscope's native image plane. We present an extended optical model for our wavefront coded light field microscope and develop a performance metric based on Fisher information, which we use to choose adequate phase masks parameters. We validate our approach using both simulated data and experimental resolution measurements of a USAF 1951 resolution target; and demonstrate the utility for biological applications with in vivo volumetric calcium imaging of larval zebrafish brain.

  19. Enhancing spatial resolution of (18)F positron imaging with the Timepix detector by classification of primary fired pixels using support vector machine.

    PubMed

    Wang, Qian; Liu, Zhen; Ziegler, Sibylle I; Shi, Kuangyu

    2015-07-07

    Position-sensitive positron cameras using silicon pixel detectors have been applied for some preclinical and intraoperative clinical applications. However, the spatial resolution of a positron camera is limited by positron multiple scattering in the detector. An incident positron may fire a number of successive pixels on the imaging plane. It is still impossible to capture the primary fired pixel along a particle trajectory by hardware or to perceive the pixel firing sequence by direct observation. Here, we propose a novel data-driven method to improve the spatial resolution by classifying the primary pixels within the detector using support vector machine. A classification model is constructed by learning the features of positron trajectories based on Monte-Carlo simulations using Geant4. Topological and energy features of pixels fired by (18)F positrons were considered for the training and classification. After applying the classification model on measurements, the primary fired pixels of the positron tracks in the silicon detector were estimated. The method was tested and assessed for [(18)F]FDG imaging of an absorbing edge protocol and a leaf sample. The proposed method improved the spatial resolution from 154.6   ±   4.2 µm (energy weighted centroid approximation) to 132.3   ±   3.5 µm in the absorbing edge measurements. For the positron imaging of a leaf sample, the proposed method achieved lower root mean square error relative to phosphor plate imaging, and higher similarity with the reference optical image. The improvements of the preliminary results support further investigation of the proposed algorithm for the enhancement of positron imaging in clinical and preclinical applications.

  20. Enhancing spatial resolution of 18F positron imaging with the Timepix detector by classification of primary fired pixels using support vector machine

    NASA Astrophysics Data System (ADS)

    Wang, Qian; Liu, Zhen; Ziegler, Sibylle I.; Shi, Kuangyu

    2015-07-01

    Position-sensitive positron cameras using silicon pixel detectors have been applied for some preclinical and intraoperative clinical applications. However, the spatial resolution of a positron camera is limited by positron multiple scattering in the detector. An incident positron may fire a number of successive pixels on the imaging plane. It is still impossible to capture the primary fired pixel along a particle trajectory by hardware or to perceive the pixel firing sequence by direct observation. Here, we propose a novel data-driven method to improve the spatial resolution by classifying the primary pixels within the detector using support vector machine. A classification model is constructed by learning the features of positron trajectories based on Monte-Carlo simulations using Geant4. Topological and energy features of pixels fired by 18F positrons were considered for the training and classification. After applying the classification model on measurements, the primary fired pixels of the positron tracks in the silicon detector were estimated. The method was tested and assessed for [18F]FDG imaging of an absorbing edge protocol and a leaf sample. The proposed method improved the spatial resolution from 154.6   ±   4.2 µm (energy weighted centroid approximation) to 132.3   ±   3.5 µm in the absorbing edge measurements. For the positron imaging of a leaf sample, the proposed method achieved lower root mean square error relative to phosphor plate imaging, and higher similarity with the reference optical image. The improvements of the preliminary results support further investigation of the proposed algorithm for the enhancement of positron imaging in clinical and preclinical applications.

  1. SU-C-207A-01: A Novel Maximum Likelihood Method for High-Resolution Proton Radiography/proton CT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Collins-Fekete, C; Centre Hospitalier University de Quebec, Quebec, QC; Mass General Hospital

    2016-06-15

    Purpose: Multiple Coulomb scattering is the largest contributor to blurring in proton imaging. Here we tested a maximum likelihood least squares estimator (MLLSE) to improve the spatial resolution of proton radiography (pRad) and proton computed tomography (pCT). Methods: The object is discretized into voxels and the average relative stopping power through voxel columns defined from the source to the detector pixels is optimized such that it maximizes the likelihood of the proton energy loss. The length spent by individual protons in each column is calculated through an optimized cubic spline estimate. pRad images were first produced using Geant4 simulations. Anmore » anthropomorphic head phantom and the Catphan line-pair module for 3-D spatial resolution were studied and resulting images were analyzed. Both parallel and conical beam have been investigated for simulated pRad acquisition. Then, experimental data of a pediatric head phantom (CIRS) were acquired using a recently completed experimental pCT scanner. Specific filters were applied on proton angle and energy loss data to remove proton histories that underwent nuclear interactions. The MTF10% (lp/mm) was used to evaluate and compare spatial resolution. Results: Numerical simulations showed improvement in the pRad spatial resolution for the parallel (2.75 to 6.71 lp/cm) and conical beam (3.08 to 5.83 lp/cm) reconstructed with the MLLSE compared to averaging detector pixel signals. For full tomographic reconstruction, the improved pRad were used as input into a simultaneous algebraic reconstruction algorithm. The Catphan pCT reconstruction based on the MLLSE-enhanced projection showed spatial resolution improvement for the parallel (2.83 to 5.86 lp/cm) and conical beam (3.03 to 5.15 lp/cm). The anthropomorphic head pCT displayed important contrast gains in high-gradient regions. Experimental results also demonstrated significant improvement in spatial resolution of the pediatric head radiography. Conclusion: The proposed MLLSE shows promising potential to increase the spatial resolution (up to 244%) in proton imaging.« less

  2. Area-to-point regression kriging for pan-sharpening

    NASA Astrophysics Data System (ADS)

    Wang, Qunming; Shi, Wenzhong; Atkinson, Peter M.

    2016-04-01

    Pan-sharpening is a technique to combine the fine spatial resolution panchromatic (PAN) band with the coarse spatial resolution multispectral bands of the same satellite to create a fine spatial resolution multispectral image. In this paper, area-to-point regression kriging (ATPRK) is proposed for pan-sharpening. ATPRK considers the PAN band as the covariate. Moreover, ATPRK is extended with a local approach, called adaptive ATPRK (AATPRK), which fits a regression model using a local, non-stationary scheme such that the regression coefficients change across the image. The two geostatistical approaches, ATPRK and AATPRK, were compared to the 13 state-of-the-art pan-sharpening approaches summarized in Vivone et al. (2015) in experiments on three separate datasets. ATPRK and AATPRK produced more accurate pan-sharpened images than the 13 benchmark algorithms in all three experiments. Unlike the benchmark algorithms, the two geostatistical solutions precisely preserved the spectral properties of the original coarse data. Furthermore, ATPRK can be enhanced by a local scheme in AATRPK, in cases where the residuals from a global regression model are such that their spatial character varies locally.

  3. Pan-sharpening algorithm to remove thin cloud via mask dodging and nonsampled shift-invariant shearlet transform

    NASA Astrophysics Data System (ADS)

    Shi, Cheng; Liu, Fang; Li, Ling-Ling; Hao, Hong-Xia

    2014-01-01

    The goal of pan-sharpening is to get an image with higher spatial resolution and better spectral information. However, the resolution of the pan-sharpened image is seriously affected by the thin clouds. For a single image, filtering algorithms are widely used to remove clouds. These kinds of methods can remove clouds effectively, but the detail lost in the cloud removal image is also serious. To solve this problem, a pan-sharpening algorithm to remove thin cloud via mask dodging and nonsampled shift-invariant shearlet transform (NSST) is proposed. For the low-resolution multispectral (LR MS) and high-resolution panchromatic images with thin clouds, a mask dodging method is used to remove clouds. For the cloud removal LR MS image, an adaptive principal component analysis transform is proposed to balance the spectral information and spatial resolution in the pan-sharpened image. Since the clouds removal process causes the detail loss problem, a weight matrix is designed to enhance the details of the cloud regions in the pan-sharpening process, but noncloud regions remain unchanged. And the details of the image are obtained by NSST. Experimental results over visible and evaluation metrics demonstrate that the proposed method can keep better spectral information and spatial resolution, especially for the images with thin clouds.

  4. Satellite image time series simulation for environmental monitoring

    NASA Astrophysics Data System (ADS)

    Guo, Tao

    2014-11-01

    The performance of environmental monitoring heavily depends on the availability of consecutive observation data and it turns out an increasing demand in remote sensing community for satellite image data in the sufficient resolution with respect to both spatial and temporal requirements, which appear to be conflictive and hard to tune tradeoffs. Multiple constellations could be a solution if without concerning cost, and thus it is so far interesting but very challenging to develop a method which can simultaneously improve both spatial and temporal details. There are some research efforts to deal with the problem from various aspects, a type of approaches is to enhance the spatial resolution using techniques of super resolution, pan-sharpen etc. which can produce good visual effects, but mostly cannot preserve spectral signatures and result in losing analytical value. Another type is to fill temporal frequency gaps by adopting time interpolation, which actually doesn't increase informative context at all. In this paper we presented a novel method to generate satellite images in higher spatial and temporal details, which further enables satellite image time series simulation. Our method starts with a pair of high-low resolution data set, and then a spatial registration is done by introducing LDA model to map high and low resolution pixels correspondingly. Afterwards, temporal change information is captured through a comparison of low resolution time series data, and the temporal change is then projected onto high resolution data plane and assigned to each high resolution pixel referring the predefined temporal change patterns of each type of ground objects to generate a simulated high resolution data. A preliminary experiment shows that our method can simulate a high resolution data with a good accuracy. We consider the contribution of our method is to enable timely monitoring of temporal changes through analysis of low resolution images time series only, and usage of costly high resolution data can be reduced as much as possible, and it presents an efficient solution with great cost performance to build up an economically operational monitoring service for environment, agriculture, forest, land use investigation, and other applications.

  5. Enhanced resolution imaging of ultrathin ZnO layers on Ag(111) by multiple hydrogen molecules in a scanning tunneling microscope junction

    NASA Astrophysics Data System (ADS)

    Liu, Shuyi; Shiotari, Akitoshi; Baugh, Delroy; Wolf, Martin; Kumagai, Takashi

    2018-05-01

    Molecular hydrogen in a scanning tunneling microscope (STM) junction has been found to enhance the lateral spatial resolution of the STM imaging, referred to as scanning tunneling hydrogen microscopy (STHM). Here we report atomic resolution imaging of 2- and 3-monolayer (ML) thick ZnO layers epitaxially grown on Ag(111) using STHM. The enhanced resolution can be obtained at a relatively large tip to surface distance and resolves a more defective structure exhibiting dislocation defects for 3-ML-thick ZnO than for 2 ML. In order to elucidate the enhanced imaging mechanism, the electric and mechanical properties of the hydrogen molecular junction (HMJ) are investigated by a combination of STM and atomic force microscopy. It is found that the HMJ shows multiple kinklike features in the tip to surface distance dependence of the conductance and frequency shift curves, which are absent in a hydrogen-free junction. Based on a simple modeling, we propose that the junction contains several hydrogen molecules and sequential squeezing of the molecules out of the junction results in the kinklike features in the conductance and frequency shift curves. The model also qualitatively reproduces the enhanced resolution image of the ZnO films.

  6. High-resolution whole-brain DCE-MRI using constrained reconstruction: Prospective clinical evaluation in brain tumor patients.

    PubMed

    Guo, Yi; Lebel, R Marc; Zhu, Yinghua; Lingala, Sajan Goud; Shiroishi, Mark S; Law, Meng; Nayak, Krishna

    2016-05-01

    To clinically evaluate a highly accelerated T1-weighted dynamic contrast-enhanced (DCE) MRI technique that provides high spatial resolution and whole-brain coverage via undersampling and constrained reconstruction with multiple sparsity constraints. Conventional (rate-2 SENSE) and experimental DCE-MRI (rate-30) scans were performed 20 minutes apart in 15 brain tumor patients. The conventional clinical DCE-MRI had voxel dimensions 0.9 × 1.3 × 7.0 mm(3), FOV 22 × 22 × 4.2 cm(3), and the experimental DCE-MRI had voxel dimensions 0.9 × 0.9 × 1.9 mm(3), and broader coverage 22 × 22 × 19 cm(3). Temporal resolution was 5 s for both protocols. Time-resolved images and blood-brain barrier permeability maps were qualitatively evaluated by two radiologists. The experimental DCE-MRI scans showed no loss of qualitative information in any of the cases, while achieving substantially higher spatial resolution and whole-brain spatial coverage. Average qualitative scores (from 0 to 3) were 2.1 for the experimental scans and 1.1 for the conventional clinical scans. The proposed DCE-MRI approach provides clinically superior image quality with higher spatial resolution and coverage than currently available approaches. These advantages may allow comprehensive permeability mapping in the brain, which is especially valuable in the setting of large lesions or multiple lesions spread throughout the brain.

  7. Electrophysiological Source Imaging: A Noninvasive Window to Brain Dynamics.

    PubMed

    He, Bin; Sohrabpour, Abbas; Brown, Emery; Liu, Zhongming

    2018-06-04

    Brain activity and connectivity are distributed in the three-dimensional space and evolve in time. It is important to image brain dynamics with high spatial and temporal resolution. Electroencephalography (EEG) and magnetoencephalography (MEG) are noninvasive measurements associated with complex neural activations and interactions that encode brain functions. Electrophysiological source imaging estimates the underlying brain electrical sources from EEG and MEG measurements. It offers increasingly improved spatial resolution and intrinsically high temporal resolution for imaging large-scale brain activity and connectivity on a wide range of timescales. Integration of electrophysiological source imaging and functional magnetic resonance imaging could further enhance spatiotemporal resolution and specificity to an extent that is not attainable with either technique alone. We review methodological developments in electrophysiological source imaging over the past three decades and envision its future advancement into a powerful functional neuroimaging technology for basic and clinical neuroscience applications.

  8. Combining HJ CCD, GF-1 WFV and MODIS Data to Generate Daily High Spatial Resolution Synthetic Data for Environmental Process Monitoring.

    PubMed

    Wu, Mingquan; Huang, Wenjiang; Niu, Zheng; Wang, Changyao

    2015-08-20

    The limitations of satellite data acquisition mean that there is a lack of satellite data with high spatial and temporal resolutions for environmental process monitoring. In this study, we address this problem by applying the Enhanced Spatial and Temporal Adaptive Reflectance Fusion Model (ESTARFM) and the Spatial and Temporal Data Fusion Approach (STDFA) to combine Huanjing satellite charge coupled device (HJ CCD), Gaofen satellite no. 1 wide field of view camera (GF-1 WFV) and Moderate Resolution Imaging Spectroradiometer (MODIS) data to generate daily high spatial resolution synthetic data for land surface process monitoring. Actual HJ CCD and GF-1 WFV data were used to evaluate the precision of the synthetic images using the correlation analysis method. Our method was tested and validated for two study areas in Xinjiang Province, China. The results show that both the ESTARFM and STDFA can be applied to combine HJ CCD and MODIS reflectance data, and GF-1 WFV and MODIS reflectance data, to generate synthetic HJ CCD data and synthetic GF-1 WFV data that closely match actual data with correlation coefficients (r) greater than 0.8989 and 0.8643, respectively. Synthetic red- and near infrared (NIR)-band data generated by ESTARFM are more suitable for the calculation of Normalized Different Vegetation Index (NDVI) than the data generated by STDFA.

  9. Combining HJ CCD, GF-1 WFV and MODIS Data to Generate Daily High Spatial Resolution Synthetic Data for Environmental Process Monitoring

    PubMed Central

    Wu, Mingquan; Huang, Wenjiang; Niu, Zheng; Wang, Changyao

    2015-01-01

    The limitations of satellite data acquisition mean that there is a lack of satellite data with high spatial and temporal resolutions for environmental process monitoring. In this study, we address this problem by applying the Enhanced Spatial and Temporal Adaptive Reflectance Fusion Model (ESTARFM) and the Spatial and Temporal Data Fusion Approach (STDFA) to combine Huanjing satellite charge coupled device (HJ CCD), Gaofen satellite no. 1 wide field of view camera (GF-1 WFV) and Moderate Resolution Imaging Spectroradiometer (MODIS) data to generate daily high spatial resolution synthetic data for land surface process monitoring. Actual HJ CCD and GF-1 WFV data were used to evaluate the precision of the synthetic images using the correlation analysis method. Our method was tested and validated for two study areas in Xinjiang Province, China. The results show that both the ESTARFM and STDFA can be applied to combine HJ CCD and MODIS reflectance data, and GF-1 WFV and MODIS reflectance data, to generate synthetic HJ CCD data and synthetic GF-1 WFV data that closely match actual data with correlation coefficients (r) greater than 0.8989 and 0.8643, respectively. Synthetic red- and near infrared (NIR)-band data generated by ESTARFM are more suitable for the calculation of Normalized Different Vegetation Index (NDVI) than the data generated by STDFA. PMID:26308017

  10. Raman Imaging in Cell Membranes, Lipid-Rich Organelles, and Lipid Bilayers.

    PubMed

    Syed, Aleem; Smith, Emily A

    2017-06-12

    Raman-based optical imaging is a promising analytical tool for noninvasive, label-free chemical imaging of lipid bilayers and cellular membranes. Imaging using spontaneous Raman scattering suffers from a low intensity that hinders its use in some cellular applications. However, developments in coherent Raman imaging, surface-enhanced Raman imaging, and tip-enhanced Raman imaging have enabled video-rate imaging, excellent detection limits, and nanometer spatial resolution, respectively. After a brief introduction to these commonly used Raman imaging techniques for cell membrane studies, this review discusses selected applications of these modalities for chemical imaging of membrane proteins and lipids. Finally, recent developments in chemical tags for Raman imaging and their applications in the analysis of selected cell membrane components are summarized. Ongoing developments toward improving the temporal and spatial resolution of Raman imaging and small-molecule tags with strong Raman scattering cross sections continue to expand the utility of Raman imaging for diverse cell membrane studies.

  11. Enhanced EDX images by fusion of multimodal SEM images using pansharpening techniques.

    PubMed

    Franchi, G; Angulo, J; Moreaud, M; Sorbier, L

    2018-01-01

    The goal of this paper is to explore the potential interest of image fusion in the context of multimodal scanning electron microscope (SEM) imaging. In particular, we aim at merging the backscattered electron images that usually have a high spatial resolution but do not provide enough discriminative information to physically classify the nature of the sample, with energy-dispersive X-ray spectroscopy (EDX) images that have discriminative information but a lower spatial resolution. The produced images are named enhanced EDX. To achieve this goal, we have compared the results obtained with classical pansharpening techniques for image fusion with an original approach tailored for multimodal SEM fusion of information. Quantitative assessment is obtained by means of two SEM images and a simulated dataset produced by a software based on PENELOPE. © 2017 The Authors Journal of Microscopy © 2017 Royal Microscopical Society.

  12. Distinguishing Individual DNA Bases in a Network by Non-Resonant Tip-Enhanced Raman Scattering.

    PubMed

    Zhang, Rui; Zhang, Xianbiao; Wang, Huifang; Zhang, Yao; Jiang, Song; Hu, Chunrui; Zhang, Yang; Luo, Yi; Dong, Zhenchao

    2017-05-08

    The importance of identifying DNA bases at the single-molecule level is well recognized for many biological applications. Although such identification can be achieved by electrical measurements using special setups, it is still not possible to identify single bases in real space by optical means owing to the diffraction limit. Herein, we demonstrate the outstanding ability of scanning tunneling microscope (STM)-controlled non-resonant tip-enhanced Raman scattering (TERS) to unambiguously distinguish two individual complementary DNA bases (adenine and thymine) with a spatial resolution down to 0.9 nm. The distinct Raman fingerprints identified for the two molecules allow to differentiate in real space individual DNA bases in coupled base pairs. The demonstrated ability of non-resonant Raman scattering with super-high spatial resolution will significantly extend the applicability of TERS, opening up new routes for single-molecule DNA sequencing. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Laser ablation surface-enhanced Raman microspectroscopy.

    PubMed

    Londero, Pablo S; Lombardi, John R; Leona, Marco

    2013-06-04

    Improved identification of trace organic compounds in complex matrixes is critical for a variety of fields such as material science, heritage science, and forensics. Surface-enhanced Raman scattering (SERS) is a vibrational spectroscopy technique that can attain single-molecule sensitivity and has been shown to complement mass spectrometry, but lacks widespread application without a robust method that utilizes the effect. We demonstrate a new, highly sensitive, and widely applicable approach to SERS analysis based on laser ablation in the presence of a tailored plasmonic substrate. We analyze several challenging compounds, including non-water-soluble pigments and dyed leather from an ancient Egyptian chariot, achieving sensitivity as high as 120 amol for a 1:1 signal-to-noise ratio and 5 μm spatial resolution. This represents orders of magnitude improvement in spatial resolution and sensitivity compared to those of other SERS approaches intended for widespread application, greatly increasing the applicability of SERS.

  14. High resolution remote sensing of densely urbanised regions: a case study of Hong Kong.

    PubMed

    Nichol, Janet E; Wong, Man Sing

    2009-01-01

    Data on the urban environment such as climate or air quality is usually collected at a few point monitoring stations distributed over a city. However, the synoptic viewpoint of satellites where a whole city is visible on a single image permits the collection of spatially comprehensive data at city-wide scale. In spite of rapid developments in remote sensing systems, deficiencies in image resolution and algorithm development still exist for applications such as air quality monitoring and urban heat island analysis. This paper describes state-of-the-art techniques for enhancing and maximising the spatial detail available from satellite images, and demonstrates their applications to the densely urbanised environment of Hong Kong. An Emissivity Modulation technique for spatial enhancement of thermal satellite images permits modelling of urban microclimate in combination with other urban structural parameters at local scale. For air quality monitoring, a Minimum Reflectance Technique (MRT) has been developed for MODIS 500 m images. The techniques described can promote the routine utilization of remotely sensed images for environmental monitoring in cities of the 21(st) century.

  15. High Resolution Remote Sensing of Densely Urbanised Regions: a Case Study of Hong Kong

    PubMed Central

    Nichol, Janet E.; Wong, Man Sing

    2009-01-01

    Data on the urban environment such as climate or air quality is usually collected at a few point monitoring stations distributed over a city. However, the synoptic viewpoint of satellites where a whole city is visible on a single image permits the collection of spatially comprehensive data at city-wide scale. In spite of rapid developments in remote sensing systems, deficiencies in image resolution and algorithm development still exist for applications such as air quality monitoring and urban heat island analysis. This paper describes state-of-the-art techniques for enhancing and maximising the spatial detail available from satellite images, and demonstrates their applications to the densely urbanised environment of Hong Kong. An Emissivity Modulation technique for spatial enhancement of thermal satellite images permits modelling of urban microclimate in combination with other urban structural parameters at local scale. For air quality monitoring, a Minimum Reflectance Technique (MRT) has been developed for MODIS 500 m images. The techniques described can promote the routine utilization of remotely sensed images for environmental monitoring in cities of the 21st century. PMID:22408549

  16. Snowmelt Pattern and Lake Ice Phenology around Tibetan Plateau Estimated from Enhanced Resolution Passive Microwave Data

    NASA Astrophysics Data System (ADS)

    Xiong, C.; Shi, J.; Wang, T.

    2017-12-01

    Snow and ice is very sensitive to the climate change. Rising air temperature will cause the snowmelt time change. In contrast, the change in snow state will have feedback on climate through snow albedo. The snow melt timing is also correlated with the associated runoff. Ice phenology describes the seasonal cycle of lake ice cover and includes freeze-up and breakup periods and ice cover duration, which is an important weather and climate indicator. It is also important for lake-atmosphere interactions and hydrological and ecological processes. The enhanced resolution (up to 3.125 km) passive microwave data is used to estimate the snowmelt pattern and lake ice phenology on and around Tibetan Plateau. The enhanced resolution makes the estimation of snowmelt and lake ice phenology in more spatial detail compared to previous 25 km gridded passive microwave data. New algorithm based on smooth filters and change point detection was developed to estimate the snowmelt and lake ice freeze-up and break-up timing. Spatial and temporal pattern of snowmelt and lake ice phonology are estimated. This study provides an objective evidence of climate change impact on the cryospheric system on Tibetan Plateau. The results show significant earlier snowmelt and lake ice break-up in some regions.

  17. Unlocking the spatial inversion of large scanning magnetic microscopy datasets

    NASA Astrophysics Data System (ADS)

    Myre, J. M.; Lascu, I.; Andrade Lima, E.; Feinberg, J. M.; Saar, M. O.; Weiss, B. P.

    2013-12-01

    Modern scanning magnetic microscopy provides the ability to perform high-resolution, ultra-high sensitivity moment magnetometry, with spatial resolutions better than 10^-4 m and magnetic moments as weak as 10^-16 Am^2. These microscopy capabilities have enhanced numerous magnetic studies, including investigations of the paleointensity of the Earth's magnetic field, shock magnetization and demagnetization of impacts, magnetostratigraphy, the magnetic record in speleothems, and the records of ancient core dynamos of planetary bodies. A common component among many studies utilizing scanning magnetic microscopy is solving an inverse problem to determine the non-negative magnitude of the magnetic moments that produce the measured component of the magnetic field. The two most frequently used methods to solve this inverse problem are classic fast Fourier techniques in the frequency domain and non-negative least squares (NNLS) methods in the spatial domain. Although Fourier techniques are extremely fast, they typically violate non-negativity and it is difficult to implement constraints associated with the space domain. NNLS methods do not violate non-negativity, but have typically been computation time prohibitive for samples of practical size or resolution. Existing NNLS methods use multiple techniques to attain tractable computation. To reduce computation time in the past, typically sample size or scan resolution would have to be reduced. Similarly, multiple inversions of smaller sample subdivisions can be performed, although this frequently results in undesirable artifacts at subdivision boundaries. Dipole interactions can also be filtered to only compute interactions above a threshold which enables the use of sparse methods through artificial sparsity. To improve upon existing spatial domain techniques, we present the application of the TNT algorithm, named TNT as it is a "dynamite" non-negative least squares algorithm which enhances the performance and accuracy of spatial domain inversions. We show that the TNT algorithm reduces the execution time of spatial domain inversions from months to hours and that inverse solution accuracy is improved as the TNT algorithm naturally produces solutions with small norms. Using sIRM and NRM measures of multiple synthetic and natural samples we show that the capabilities of the TNT algorithm allow very large samples to be inverted without the need for alternative techniques to make the problems tractable. Ultimately, the TNT algorithm enables accurate spatial domain analysis of scanning magnetic microscopy data on an accelerated time scale that renders spatial domain analyses tractable for numerous studies, including searches for the best fit of unidirectional magnetization direction and high-resolution step-wise magnetization and demagnetization.

  18. Sidelobe apodization in optical pulse compression reflectometry for fiber optic distributed acoustic sensing.

    PubMed

    Mompó, Juan José; Martín-López, Sonia; González-Herráez, Miguel; Loayssa, Alayn

    2018-04-01

    We demonstrate a technique to reduce the sidelobes in optical pulse compression reflectometry for distributed acoustic sensing. The technique is based on using a Gaussian probe pulse with linear frequency modulation. This is shown to improve the sidelobe suppression by 13 dB compared to the use of square pulses without any significant penalty in terms of spatial resolution. In addition, a 2.25 dB enhancement in signal-to-noise ratio is calculated compared to the use of receiver-side windowing. The method is tested by measuring 700 Hz vibrations with a 140  nε amplitude at the end of a 50 km fiber sensing link with 34 cm spatial resolution, giving a record 147,058 spatially resolved points.

  19. Classification of High Spatial Resolution, Hyperspectral ...

    EPA Pesticide Factsheets

    EPA announced the availability of the final report,

  20. Surface Variability of Short-wavelength Radiation and Temperature on Exoplanets around M Dwarfs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Xin; Tian, Feng; Wang, Yuwei

    2017-03-10

    It is a common practice to use 3D General Circulation Models (GCM) with spatial resolution of a few hundred kilometers to simulate the climate of Earth-like exoplanets. The enhanced albedo effect of clouds is especially important for exoplanets in the habitable zones around M dwarfs that likely have fixed substellar regions and substantial cloud coverage. Here, we carry out mesoscale model simulations with 3 km spatial resolution driven by the initial and boundary conditions in a 3D GCM and find that it could significantly underestimate the spatial variability of both the incident short-wavelength radiation and the temperature at planet surface.more » Our findings suggest that mesoscale models with cloud-resolving capability be considered for future studies of exoplanet climate.« less

  1. Hollow Cone Electron Imaging for Single Particle 3D Reconstruction of Proteins

    PubMed Central

    Tsai, Chun-Ying; Chang, Yuan-Chih; Lobato, Ivan; Van Dyck, Dirk; Chen, Fu-Rong

    2016-01-01

    The main bottlenecks for high-resolution biological imaging in electron microscopy are radiation sensitivity and low contrast. The phase contrast at low spatial frequencies can be enhanced by using a large defocus but this strongly reduces the resolution. Recently, phase plates have been developed to enhance the contrast at small defocus but electrical charging remains a problem. Single particle cryo-electron microscopy is mostly used to minimize the radiation damage and to enhance the resolution of the 3D reconstructions but it requires averaging images of a massive number of individual particles. Here we present a new route to achieve the same goals by hollow cone dark field imaging using thermal diffuse scattered electrons giving about a 4 times contrast increase as compared to bright field imaging. We demonstrate the 3D reconstruction of a stained GroEL particle can yield about 13.5 Å resolution but using a strongly reduced number of images. PMID:27292544

  2. A micropixelated ion-imaging detector for mass resolution enhancement of a QMS instrument.

    PubMed

    Syed, Sarfaraz U A H; Eijkel, Gert B; Maher, Simon; Kistemaker, Piet; Taylor, Stephen; Heeren, Ron M A

    2015-03-01

    An in-vacuum position-sensitive micropixelated detector (Timepix) is used to investigate the time-dependent spatial distribution of different charge state (and hence different mass-to-charge (m/z)) ions exiting an electrospray ionization (ESI)-based quadrupole mass spectrometer (QMS) instrument. Ion images obtained from the Timepix detector provide a detailed insight into the positions of stable and unstable ions of the mass peak as they exit the QMS. With the help of image processing algorithms and by selecting areas on the ion images where more stable ions impact the detector, an improvement in mass resolution by a factor of 5 was obtained for certain operating conditions. Moreover, our experimental approach of mass resolution enhancement was confirmed by in-house-developed novel QMS instrument simulation software. Utilizing the imaging-based mass resolution enhancement approach, the software predicts instrument mass resolution of ∼1,0000 for a single-filter QMS instrument with a 210-mm long mass filter and a low operating frequency (880 kHz) of the radio frequency (RF) voltage.

  3. Stennis Space Center Verification & Validation Capabilities

    NASA Technical Reports Server (NTRS)

    Pagnutti, Mary; Ryan, Robert E.; Holekamp, Kara; O'Neal, Duane; Knowlton, Kelly; Ross, Kenton; Blonski, Slawomir

    2007-01-01

    Scientists within NASA#s Applied Research & Technology Project Office (formerly the Applied Sciences Directorate) have developed a well-characterized remote sensing Verification & Validation (V&V) site at the John C. Stennis Space Center (SSC). This site enables the in-flight characterization of satellite and airborne high spatial resolution remote sensing systems and their products. The smaller scale of the newer high resolution remote sensing systems allows scientists to characterize geometric, spatial, and radiometric data properties using a single V&V site. The targets and techniques used to characterize data from these newer systems can differ significantly from the techniques used to characterize data from the earlier, coarser spatial resolution systems. Scientists have used the SSC V&V site to characterize thermal infrared systems. Enhancements are being considered to characterize active lidar systems. SSC employs geodetic targets, edge targets, radiometric tarps, atmospheric monitoring equipment, and thermal calibration ponds to characterize remote sensing data products. Similar techniques are used to characterize moderate spatial resolution sensing systems at selected nearby locations. The SSC Instrument Validation Lab is a key component of the V&V capability and is used to calibrate field instrumentation and to provide National Institute of Standards and Technology traceability. This poster presents a description of the SSC characterization capabilities and examples of calibration data.

  4. A deterministic model of electron transport for electron probe microanalysis

    NASA Astrophysics Data System (ADS)

    Bünger, J.; Richter, S.; Torrilhon, M.

    2018-01-01

    Within the last decades significant improvements in the spatial resolution of electron probe microanalysis (EPMA) were obtained by instrumental enhancements. In contrast, the quantification procedures essentially remained unchanged. As the classical procedures assume either homogeneity or a multi-layered structure of the material, they limit the spatial resolution of EPMA. The possibilities of improving the spatial resolution through more sophisticated quantification procedures are therefore almost untouched. We investigate a new analytical model (M 1-model) for the quantification procedure based on fast and accurate modelling of electron-X-ray-matter interactions in complex materials using a deterministic approach to solve the electron transport equations. We outline the derivation of the model from the Boltzmann equation for electron transport using the method of moments with a minimum entropy closure and present first numerical results for three different test cases (homogeneous, thin film and interface). Taking Monte Carlo as a reference, the results for the three test cases show that the M 1-model is able to reproduce the electron dynamics in EPMA applications very well. Compared to classical analytical models like XPP and PAP, the M 1-model is more accurate and far more flexible, which indicates the potential of deterministic models of electron transport to further increase the spatial resolution of EPMA.

  5. Atomic-Scale Nuclear Spin Imaging Using Quantum-Assisted Sensors in Diamond

    NASA Astrophysics Data System (ADS)

    Ajoy, A.; Bissbort, U.; Lukin, M. D.; Walsworth, R. L.; Cappellaro, P.

    2015-01-01

    Nuclear spin imaging at the atomic level is essential for the understanding of fundamental biological phenomena and for applications such as drug discovery. The advent of novel nanoscale sensors promises to achieve the long-standing goal of single-protein, high spatial-resolution structure determination under ambient conditions. In particular, quantum sensors based on the spin-dependent photoluminescence of nitrogen-vacancy (NV) centers in diamond have recently been used to detect nanoscale ensembles of external nuclear spins. While NV sensitivity is approaching single-spin levels, extracting relevant information from a very complex structure is a further challenge since it requires not only the ability to sense the magnetic field of an isolated nuclear spin but also to achieve atomic-scale spatial resolution. Here, we propose a method that, by exploiting the coupling of the NV center to an intrinsic quantum memory associated with the nitrogen nuclear spin, can reach a tenfold improvement in spatial resolution, down to atomic scales. The spatial resolution enhancement is achieved through coherent control of the sensor spin, which creates a dynamic frequency filter selecting only a few nuclear spins at a time. We propose and analyze a protocol that would allow not only sensing individual spins in a complex biomolecule, but also unraveling couplings among them, thus elucidating local characteristics of the molecule structure.

  6. Graphene Oxide as a Novel Evenly Continuous Phase Matrix for TOF-SIMS.

    PubMed

    Cai, Lesi; Sheng, Linfeng; Xia, Mengchan; Li, Zhanping; Zhang, Sichun; Zhang, Xinrong; Chen, Hongyuan

    2017-03-01

    Using matrix to enhance the molecular ion signals for biomolecule identification without loss of spatial resolution caused by matrix crystallization is a great challenge for the application of TOF-SIMS in real-world biological research. In this report, graphene oxide (GO) was used as a matrix for TOF-SIMS to improve the secondary ion yields of intact molecular ions ([M + H] + ). Identifying and distinguishing the molecular ions of lipids (m/z >700) therefore became straightforward. The spatial resolution of TOF-SIMS imaging could also be improved as GO can form a homogeneous layer of matrix instead of crystalline domain, which prevents high spatial resolution in TOF-SIMS imaging. Lipid mapping in presence of GO revealed the delicate morphology and distribution of single vesicles with a diameter of 800 nm. On GO matrix, the vesicles with similar shape but different chemical composition could be distinguished using molecular ions. This novel matrix holds potentials in such applications as the analysis and imaging of complex biological samples by TOF-SIMS. Graphical Abstract ᅟ.

  7. Phase-based, high spatial resolution and distributed, static and dynamic strain sensing using Brillouin dynamic gratings in optical fibers.

    PubMed

    Bergman, Arik; Langer, Tomi; Tur, Moshe

    2017-03-06

    A novel technique combining Brillouin phase-shift measurements with Brillouin dynamic gratings (BDGs) reflectometry in polarization-maintaining fibers is presented here for the first time. While a direct measurement of the optical phase in standard BDG setups is impractical due to non-local phase contributions, their detrimental effect is reduced by ~4 orders of magnitude through the coherent addition of Stokes and anti-Stokes reflections from two counter-propagating BDGs in the fiber. The technique advantageously combines the high-spatial-resolution of BDGs reflectometry with the increased tolerance to optical power fluctuations of phasorial measurements, to enhance the performance of fiber-optic strain sensors. We demonstrate a distributed measurement (20cm spatial-resolution) of both static and dynamic (5kHz of vibrations at a sampling rate of 1MHz) strain fields acting on the fiber, in good agreement with theory and (for the static case) with the results of commercial reflectometers.

  8. Graphene Oxide as a Novel Evenly Continuous Phase Matrix for TOF-SIMS

    NASA Astrophysics Data System (ADS)

    Cai, Lesi; Sheng, Linfeng; Xia, Mengchan; Li, Zhanping; Zhang, Sichun; Zhang, Xinrong; Chen, Hongyuan

    2017-03-01

    Using matrix to enhance the molecular ion signals for biomolecule identification without loss of spatial resolution caused by matrix crystallization is a great challenge for the application of TOF-SIMS in real-world biological research. In this report, graphene oxide (GO) was used as a matrix for TOF-SIMS to improve the secondary ion yields of intact molecular ions ([M + H]+). Identifying and distinguishing the molecular ions of lipids ( m/z >700) therefore became straightforward. The spatial resolution of TOF-SIMS imaging could also be improved as GO can form a homogeneous layer of matrix instead of crystalline domain, which prevents high spatial resolution in TOF-SIMS imaging. Lipid mapping in presence of GO revealed the delicate morphology and distribution of single vesicles with a diameter of 800 nm. On GO matrix, the vesicles with similar shape but different chemical composition could be distinguished using molecular ions. This novel matrix holds potentials in such applications as the analysis and imaging of complex biological samples by TOF-SIMS.

  9. Dynamical structure of extreme ultraviolet macrospicules

    NASA Technical Reports Server (NTRS)

    Karovska, Margarita; Habbal, Shadia Rifai

    1994-01-01

    We describe the substructures forming the macrospicules and their temporal evolution, as revealed by the application of an image enhancement algorithm to extreme ultraviolet (EUV) observations of macrospicules. The enhanced images uncover, for the first time, the substructures forming the column-like structures within the macrospicules and the low-lying arches at their base. The spatial and temporal evolution of macrospicules clearly show continuous interaction between these substructures with occasional ejection of plasma following a ballistic trajectory. We comment on the importance of these results for planning near future space observations of macrospicules with better temporal and spatial resolution.

  10. Nonlinear structured-illumination enhanced temporal focusing multiphoton excitation microscopy with a digital micromirror device.

    PubMed

    Cheng, Li-Chung; Lien, Chi-Hsiang; Da Sie, Yong; Hu, Yvonne Yuling; Lin, Chun-Yu; Chien, Fan-Ching; Xu, Chris; Dong, Chen Yuan; Chen, Shean-Jen

    2014-08-01

    In this study, the light diffraction of temporal focusing multiphoton excitation microscopy (TFMPEM) and the excitation patterning of nonlinear structured-illumination microscopy (NSIM) can be simultaneously and accurately implemented via a single high-resolution digital micromirror device. The lateral and axial spatial resolutions of the TFMPEM are remarkably improved through the second-order NSIM and projected structured light, respectively. The experimental results demonstrate that the lateral and axial resolutions are enhanced from 397 nm to 168 nm (2.4-fold) and from 2.33 μm to 1.22 μm (1.9-fold), respectively, in full width at the half maximum. Furthermore, a three-dimensionally rendered image of a cytoskeleton cell featuring ~25 nm microtubules is improved, with other microtubules at a distance near the lateral resolution of 168 nm also able to be distinguished.

  11. Nepal and Papua Airborne Gravity Surveys

    NASA Astrophysics Data System (ADS)

    Olesen, A. V.; Forsberg, R.; Kasenda, F.; Einarsson, I.; Manandhar, N.

    2011-12-01

    Airborne gravimetry offers a fast and economic way to cover vast areas and it allows access to otherwise difficult accessible areas like mountains, jungles and the near coastal zone. It has the potential to deliver high resolution and bias free data that may bridge the spectral gap between global satellite gravity models and the high resolution gravity information embedded in digital terrain models. DTU Space has for more than a decade done airborne gravity surveys in many parts of the world. Most surveys were done with a LaCoste & Romberg S-meter updated for airborne use. This instrument has proven to deliver near bias free data when properly processed. A Chekan AM gravimeter was recently added to the airborne gravity mapping system and will potentially enhance the spatial resolution and the robustness of the system. This paper will focus on results from two recent surveys over Nepal, flown in December 2010, and over Papua (eastern Indonesia), flown in May and June 2011. Both surveys were flown with the new double gravimeter setup and initial assessment of system performance indicates improved spatial resolution compared to the single gravimeter system. Comparison to EGM08 and to the most recent GOCE models highlights the impact of the new airborne gravity data in both cases. A newly computed geoid model for Nepal based on the airborne data allows for a more precise definition of the height of Mt. Everest in a global height system. This geoid model suggests that the height of Mt. Everest should be increased by approximately 1 meter. The paper will also briefly discuss system setup and will highlight a few essential processing steps that ensure that bias problems are minimized and spatial resolution enhanced.

  12. Flexible proton 3D MR spectroscopic imaging of the prostate with low-power adiabatic pulses for volume selection and spiral readout.

    PubMed

    Steinseifer, Isabell K; Philips, Bart W J; Gagoski, Borjan; Weiland, Elisabeth; Scheenen, Tom W J; Heerschap, Arend

    2017-03-01

    Cartesian k-space sampling in three-dimensional magnetic resonance spectroscopic imaging (MRSI) of the prostate limits the selection of voxel size and acquisition time. Therefore, large prostates are often scanned at reduced spatial resolutions to stay within clinically acceptable measurement times. Here we present a semilocalized adiabatic selective refocusing (sLASER) sequence with gradient-modulated offset-independent adiabatic (GOIA) refocusing pulses and spiral k-space acquisition (GOIA-sLASER-Spiral) for fast prostate MRSI with enhanced resolution and extended matrix sizes. MR was performed at 3 tesla with an endorectal receive coil. GOIA-sLASER-Spiral at an echo time (TE) of 90 ms was compared to a point-resolved spectroscopy sequence (PRESS) with weighted, elliptical phase encoding at an TE of 145 ms using simulations and measurements of phantoms and patients (n = 9). GOIA-sLASER-Spiral acquisition allows prostate MR spectra to be obtained in ∼5 min with a quality comparable to those acquired with a common Cartesian PRESS protocol in ∼9 min, or at an enhanced spatial resolution showing more precise tissue allocation of metabolites. Extended field of views (FOVs) and matrix sizes for large prostates are possible without compromising spatial resolution or measurement time. The flexibility of spiral sampling enables prostate MRSI with a wide range of resolutions and FOVs without undesirable increases in acquisition times, as in Cartesian encoding. This approach is suitable for routine clinical exams of prostate metabolites. Magn Reson Med 77:928-935, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  13. CAMECA IMS 1300-HR3: The New Generation Ion Microprobe

    NASA Astrophysics Data System (ADS)

    Peres, P.; Choi, S. Y.; Renaud, L.; Saliot, P.; Larson, D. J.

    2016-12-01

    The success of secondary ion mass spectrometry (SIMS) in Geo- and Cosmo-chemistry relies on its performance in terms of: 1) very high sensitivity (mandatory for high precision measurements or to achieve low detection limits); 2) a broad mass range of elemental and isotopic species, from low mass (H) to high mass (U and above); 3) in-situ analysis of any solid flat polished surface; and 4) high spatial resolution from tens of microns down to sub-micron scale. The IMS 1300-HR3 (High Reproducibility, High spatial Resolution, High mass Resolution) is the latest generation of CAMECA's large geometry magnetic sector SIMS (or ion microprobe), successor to the internationally recognized IMS 1280-HR. The 1300-HR3delivers unmatched analytical performance for a wide range of applications (stable isotopes, geochronology, trace elements, nuclear safeguards and environmental studies…) due to: • High brightness RF-plasma oxygen ion source with enhanced beam density and current stability, dramatically improving spatial resolution, data reproducibility, and throughput • Automated sample loading system with motorized sample height (Z) adjustment, significantly increasing analysis precision, ease-of-use, and productivity • UV-light microscope for enhanced optical image resolution, together with dedicated software for easy sample navigation (developed by University of Wisconsin, USA) • Low noise 1012Ω resistor Faraday cup preamplifier boards for measuring low signal intensities In addition, improvements in electronics and software have been integrated into the new instrument. In order to meet a growing demand from geochronologists, CAMECA also introduces the KLEORA, which is a fully optimized ion microprobe for advanced mineral dating derived from the IMS 1300-HR3. Instrumental developments as well as data obtained for stable isotope and U-Pb dating applications will be presented in detail.

  14. Sharpening Ejecta Patterns: Investigating Spectral Fidelity After Controlled Intensity-Hue-Saturation Image Fusion of LROC Images of Fresh Craters

    NASA Astrophysics Data System (ADS)

    Awumah, A.; Mahanti, P.; Robinson, M. S.

    2017-12-01

    Image fusion is often used in Earth-based remote sensing applications to merge spatial details from a high-resolution panchromatic (Pan) image with the color information from a lower-resolution multi-spectral (MS) image, resulting in a high-resolution multi-spectral image (HRMS). Previously, the performance of six well-known image fusion methods were compared using Lunar Reconnaissance Orbiter Camera (LROC) Narrow Angle Camera (NAC) and Wide Angle Camera (WAC) images (1). Results showed the Intensity-Hue-Saturation (IHS) method provided the best spatial performance, but deteriorated the spectral content. In general, there was a trade-off between spatial enhancement and spectral fidelity from the fusion process; the more spatial details from the Pan fused with the MS image, the more spectrally distorted the final HRMS. In this work, we control the amount of spatial details fused (from the LROC NAC images to WAC images) using a controlled IHS method (2), to investigate the spatial variation in spectral distortion on fresh crater ejecta. In the controlled IHS method (2), the percentage of the Pan component merged with the MS is varied. The percent of spatial detail from the Pan used is determined by a variable whose value may be varied between 1 (no Pan utilized) to infinity (entire Pan utilized). An HRMS color composite image (red=415nm, green=321/415nm, blue=321/360nm (3)) was used to assess performance (via visual inspection and metric-based evaluations) at each tested value of the control parameter (1 to 10—after which spectral distortion saturates—in 0.01 increments) within three regions: crater interiors, ejecta blankets, and the background material surrounding the craters. Increasing the control parameter introduced increased spatial sharpness and spectral distortion in all regions, but to varying degrees. Crater interiors suffered the most color distortion, while ejecta experienced less color distortion. The controlled IHS method is therefore desirable for resolution-enhancement of fresh crater ejecta; larger values of the control parameter may be used to sharpen MS images of ejecta patterns but with less impact to color distortion than in the uncontrolled IHS fusion process. References: (1) Prasun et. al (2016) ISPRS. (2) Choi, Myungjin (2006) IEEE. (3) Denevi et. al (2014) JGR.

  15. Texton-based super-resolution for achieving high spatiotemporal resolution in hybrid camera system

    NASA Astrophysics Data System (ADS)

    Kamimura, Kenji; Tsumura, Norimichi; Nakaguchi, Toshiya; Miyake, Yoichi

    2010-05-01

    Many super-resolution methods have been proposed to enhance the spatial resolution of images by using iteration and multiple input images. In a previous paper, we proposed the example-based super-resolution method to enhance an image through pixel-based texton substitution to reduce the computational cost. In this method, however, we only considered the enhancement of a texture image. In this study, we modified this texton substitution method for a hybrid camera to reduce the required bandwidth of a high-resolution video camera. We applied our algorithm to pairs of high- and low-spatiotemporal-resolution videos, which were synthesized to simulate a hybrid camera. The result showed that the fine detail of the low-resolution video can be reproduced compared with bicubic interpolation and the required bandwidth could be reduced to about 1/5 in a video camera. It was also shown that the peak signal-to-noise ratios (PSNRs) of the images improved by about 6 dB in a trained frame and by 1.0-1.5 dB in a test frame, as determined by comparison with the processed image using bicubic interpolation, and the average PSNRs were higher than those obtained by the well-known Freeman’s patch-based super-resolution method. Compared with that of the Freeman’s patch-based super-resolution method, the computational time of our method was reduced to almost 1/10.

  16. Multi-Image Registration for an Enhanced Vision System

    NASA Technical Reports Server (NTRS)

    Hines, Glenn; Rahman, Zia-Ur; Jobson, Daniel; Woodell, Glenn

    2002-01-01

    An Enhanced Vision System (EVS) utilizing multi-sensor image fusion is currently under development at the NASA Langley Research Center. The EVS will provide enhanced images of the flight environment to assist pilots in poor visibility conditions. Multi-spectral images obtained from a short wave infrared (SWIR), a long wave infrared (LWIR), and a color visible band CCD camera, are enhanced and fused using the Retinex algorithm. The images from the different sensors do not have a uniform data structure: the three sensors not only operate at different wavelengths, but they also have different spatial resolutions, optical fields of view (FOV), and bore-sighting inaccuracies. Thus, in order to perform image fusion, the images must first be co-registered. Image registration is the task of aligning images taken at different times, from different sensors, or from different viewpoints, so that all corresponding points in the images match. In this paper, we present two methods for registering multiple multi-spectral images. The first method performs registration using sensor specifications to match the FOVs and resolutions directly through image resampling. In the second method, registration is obtained through geometric correction based on a spatial transformation defined by user selected control points and regression analysis.

  17. Water use data to enhance scientific and policy insight

    NASA Astrophysics Data System (ADS)

    Konar, M.

    2017-12-01

    We live in an era of big data. However, water use data remains sparse. There is an urgent need to enhance both the quality and resolution of water data. Metered water use information - as opposed to estimated water use, typically based on climate - would enhance the quality of existing water databases. Metered water use data would enable the research community to evaluate the "who, where, and when" of water use. Importantly, this information would enable the scientific community to better understand decision making related to water use (i.e. the "why"), providing the insight necessary to guide policies that promote water conservation. Metered water use data is needed at a sufficient resolution (i.e. spatial, temporal, and water user) to fully resolve how water is used throughout the economy and society. Improving the quality and resolution of water use data will enable scientific understanding that can inform policy.

  18. FFT-enhanced IHS transform method for fusing high-resolution satellite images

    USGS Publications Warehouse

    Ling, Y.; Ehlers, M.; Usery, E.L.; Madden, M.

    2007-01-01

    Existing image fusion techniques such as the intensity-hue-saturation (IHS) transform and principal components analysis (PCA) methods may not be optimal for fusing the new generation commercial high-resolution satellite images such as Ikonos and QuickBird. One problem is color distortion in the fused image, which causes visual changes as well as spectral differences between the original and fused images. In this paper, a fast Fourier transform (FFT)-enhanced IHS method is developed for fusing new generation high-resolution satellite images. This method combines a standard IHS transform with FFT filtering of both the panchromatic image and the intensity component of the original multispectral image. Ikonos and QuickBird data are used to assess the FFT-enhanced IHS transform method. Experimental results indicate that the FFT-enhanced IHS transform method may improve upon the standard IHS transform and the PCA methods in preserving spectral and spatial information. ?? 2006 International Society for Photogrammetry and Remote Sensing, Inc. (ISPRS).

  19. Dynamic placement of plasmonic hotspots for super-resolution surface-enhanced Raman scattering.

    PubMed

    Ertsgaard, Christopher T; McKoskey, Rachel M; Rich, Isabel S; Lindquist, Nathan C

    2014-10-28

    In this paper, we demonstrate dynamic placement of locally enhanced plasmonic fields using holographic laser illumination of a silver nanohole array. To visualize these focused "hotspots", the silver surface was coated with various biological samples for surface-enhanced Raman spectroscopy (SERS) imaging. Due to the large field enhancements, blinking behavior of the SERS hotspots was observed and processed using a stochastic optical reconstruction microscopy algorithm enabling super-resolution localization of the hotspots to within 10 nm. These hotspots were then shifted across the surface in subwavelength (<100 nm for a wavelength of 660 nm) steps using holographic illumination from a spatial light modulator. This created a dynamic imaging and sensing surface, whereas static illumination would only have produced stationary hotspots. Using this technique, we also show that such subwavelength shifting and localization of plasmonic hotspots has potential for imaging applications. Interestingly, illuminating the surface with randomly shifting SERS hotspots was sufficient to completely fill in a wide field of view for super-resolution chemical imaging.

  20. Shell-Isolated Tip-Enhanced Raman and Fluorescence Spectroscopy.

    PubMed

    Huang, Ya-Ping; Huang, Sheng-Chao; Wang, Xiang-Jie; Bodappa, Nataraju; Li, Chao-Yu; Yin, Hao; Su, Hai-Sheng; Meng, Meng; Zhang, Hua; Ren, Bin; Yang, Zhi-Lin; Zenobi, Renato; Tian, Zhong-Qun; Li, Jian-Feng

    2018-06-18

    Tip-enhanced Raman spectroscopy can provide molecular fingerprint information with ultrahigh spatial resolution, but the tip will be easily contaminated, thus leading to artifacts. It also remains a great challenge to establish tip-enhanced fluorescence because of the quenching resulting from the proximity of the metal tip. Herein, we report shell-isolated tip-enhanced Raman and fluorescence spectroscopies by employing ultrathin shell-isolated tips fabricated by atomic layer deposition. Such shell-isolated tips not only show outstanding electromagnetic field enhancement in TERS but also exclude interference by contaminants, thus greatly promoting applications in solution. Tip-enhanced fluorescence has also been achieved using these shell-isolated tips, with enhancement factors of up to 1.7×10 3 , consistent with theoretical simulations. Furthermore, tip-enhanced Raman and fluorescence signals are acquired simultaneously, and their relative intensities can be manipulated by changing the shell thickness. This work opens a new avenue for ultrahigh resolution surface analysis using plasmon-enhanced spectroscopies. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Cross-correlation photothermal optical coherence tomography with high effective resolution.

    PubMed

    Tang, Peijun; Liu, Shaojie; Chen, Junbo; Yuan, Zhiling; Xie, Bingkai; Zhou, Jianhua; Tang, Zhilie

    2017-12-01

    We developed a cross-correlation photothermal optical coherence tomography (CC-PTOCT) system for photothermal imaging with high lateral and axial resolution. The CC-PTOCT system consists of a phase-sensitive OCT system, a modulated pumping laser, and a digital cross-correlator. The pumping laser was used to induce the photothermal effect in the sample, causing a slight phase modulation of the OCT signals. A spatial phase differentiation method was employed to reduce phase accumulation. The noise brought by the phase differentiation method and the strong background noise were suppressed efficiently by the cross-correlator, which was utilized to extract the photothermal signals from the modulated signals. Combining the cross-correlation technique with spatial phase differentiation can improve both lateral and axial resolution of the PTOCT imaging system. Clear photothermal images of blood capillaries of a mouse ear in vivo were successfully obtained with high lateral and axial resolution. The experimental results demonstrated that this system can enhance the effective transverse resolution, effective depth resolution, and contrast of the PTOCT image effectively, aiding the ongoing development of the accurate 3D functional imaging.

  2. Blind identification of full-field vibration modes of output-only structures from uniformly-sampled, possibly temporally-aliased (sub-Nyquist), video measurements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang, Yongchao; Dorn, Charles; Mancini, Tyler

    Enhancing the spatial and temporal resolution of vibration measurements and modal analysis could significantly benefit dynamic modelling, analysis, and health monitoring of structures. For example, spatially high-density mode shapes are critical for accurate vibration-based damage localization. In experimental or operational modal analysis, higher (frequency) modes, which may be outside the frequency range of the measurement, contain local structural features that can improve damage localization as well as the construction and updating of the modal-based dynamic model of the structure. In general, the resolution of vibration measurements can be increased by enhanced hardware. Traditional vibration measurement sensors such as accelerometers havemore » high-frequency sampling capacity; however, they are discrete point-wise sensors only providing sparse, low spatial sensing resolution measurements, while dense deployment to achieve high spatial resolution is expensive and results in the mass-loading effect and modification of structure's surface. Non-contact measurement methods such as scanning laser vibrometers provide high spatial and temporal resolution sensing capacity; however, they make measurements sequentially that requires considerable acquisition time. As an alternative non-contact method, digital video cameras are relatively low-cost, agile, and provide high spatial resolution, simultaneous, measurements. Combined with vision based algorithms (e.g., image correlation or template matching, optical flow, etc.), video camera based measurements have been successfully used for experimental and operational vibration measurement and subsequent modal analysis. However, the sampling frequency of most affordable digital cameras is limited to 30–60 Hz, while high-speed cameras for higher frequency vibration measurements are extremely costly. This work develops a computational algorithm capable of performing vibration measurement at a uniform sampling frequency lower than what is required by the Shannon-Nyquist sampling theorem for output-only modal analysis. In particular, the spatio-temporal uncoupling property of the modal expansion of structural vibration responses enables a direct modal decoupling of the temporally-aliased vibration measurements by existing output-only modal analysis methods, yielding (full-field) mode shapes estimation directly. Then the signal aliasing properties in modal analysis is exploited to estimate the modal frequencies and damping ratios. Furthermore, the proposed method is validated by laboratory experiments where output-only modal identification is conducted on temporally-aliased acceleration responses and particularly the temporally-aliased video measurements of bench-scale structures, including a three-story building structure and a cantilever beam.« less

  3. Blind identification of full-field vibration modes of output-only structures from uniformly-sampled, possibly temporally-aliased (sub-Nyquist), video measurements

    DOE PAGES

    Yang, Yongchao; Dorn, Charles; Mancini, Tyler; ...

    2016-12-05

    Enhancing the spatial and temporal resolution of vibration measurements and modal analysis could significantly benefit dynamic modelling, analysis, and health monitoring of structures. For example, spatially high-density mode shapes are critical for accurate vibration-based damage localization. In experimental or operational modal analysis, higher (frequency) modes, which may be outside the frequency range of the measurement, contain local structural features that can improve damage localization as well as the construction and updating of the modal-based dynamic model of the structure. In general, the resolution of vibration measurements can be increased by enhanced hardware. Traditional vibration measurement sensors such as accelerometers havemore » high-frequency sampling capacity; however, they are discrete point-wise sensors only providing sparse, low spatial sensing resolution measurements, while dense deployment to achieve high spatial resolution is expensive and results in the mass-loading effect and modification of structure's surface. Non-contact measurement methods such as scanning laser vibrometers provide high spatial and temporal resolution sensing capacity; however, they make measurements sequentially that requires considerable acquisition time. As an alternative non-contact method, digital video cameras are relatively low-cost, agile, and provide high spatial resolution, simultaneous, measurements. Combined with vision based algorithms (e.g., image correlation or template matching, optical flow, etc.), video camera based measurements have been successfully used for experimental and operational vibration measurement and subsequent modal analysis. However, the sampling frequency of most affordable digital cameras is limited to 30–60 Hz, while high-speed cameras for higher frequency vibration measurements are extremely costly. This work develops a computational algorithm capable of performing vibration measurement at a uniform sampling frequency lower than what is required by the Shannon-Nyquist sampling theorem for output-only modal analysis. In particular, the spatio-temporal uncoupling property of the modal expansion of structural vibration responses enables a direct modal decoupling of the temporally-aliased vibration measurements by existing output-only modal analysis methods, yielding (full-field) mode shapes estimation directly. Then the signal aliasing properties in modal analysis is exploited to estimate the modal frequencies and damping ratios. Furthermore, the proposed method is validated by laboratory experiments where output-only modal identification is conducted on temporally-aliased acceleration responses and particularly the temporally-aliased video measurements of bench-scale structures, including a three-story building structure and a cantilever beam.« less

  4. Enhanced Interferometry with Programmable Spatial Light Modulator

    DTIC Science & Technology

    2010-06-07

    metrolaserinc.com6-7-2010-Monday 6 Simulated by Zemax  Lenslet diameters, d, define spatial resolution over the wavefront being measured.  (sensitivity...MetroLaser Irvine, California Fitted Zernike Polynomials upto 36 terms, found and put into Zemax Simulated Cats’ eye wavefronts by ZEMAX Experimental...measurement Simulated Fringes Leftover < 0.1λ 23 Cat’s eye wavefronts by ZEMAX based on Experimental results Jtrolinger@metrolaserinc.com6-7-2010

  5. Assessment of spectral, misregistration, and spatial uncertainties inherent in the cross-calibration study

    USGS Publications Warehouse

    Chander, G.; Helder, D.L.; Aaron, David; Mishra, N.; Shrestha, A.K.

    2013-01-01

    Cross-calibration of satellite sensors permits the quantitative comparison of measurements obtained from different Earth Observing (EO) systems. Cross-calibration studies usually use simultaneous or near-simultaneous observations from several spaceborne sensors to develop band-by-band relationships through regression analysis. The investigation described in this paper focuses on evaluation of the uncertainties inherent in the cross-calibration process, including contributions due to different spectral responses, spectral resolution, spectral filter shift, geometric misregistrations, and spatial resolutions. The hyperspectral data from the Environmental Satellite SCanning Imaging Absorption SpectroMeter for Atmospheric CartograpHY and the EO-1 Hyperion, along with the relative spectral responses (RSRs) from the Landsat 7 Enhanced Thematic Mapper (TM) Plus and the Terra Moderate Resolution Imaging Spectroradiometer sensors, were used for the spectral uncertainty study. The data from Landsat 5 TM over five representative land cover types (desert, rangeland, grassland, deciduous forest, and coniferous forest) were used for the geometric misregistrations and spatial-resolution study. The spectral resolution uncertainty was found to be within 0.25%, spectral filter shift within 2.5%, geometric misregistrations within 0.35%, and spatial-resolution effects within 0.1% for the Libya 4 site. The one-sigma uncertainties presented in this paper are uncorrelated, and therefore, the uncertainties can be summed orthogonally. Furthermore, an overall total uncertainty was developed. In general, the results suggested that the spectral uncertainty is more dominant compared to other uncertainties presented in this paper. Therefore, the effect of the sensor RSR differences needs to be quantified and compensated to avoid large uncertainties in cross-calibration results.

  6. Single Photon Counting Large Format Imaging Sensors with High Spatial and Temporal Resolution

    NASA Astrophysics Data System (ADS)

    Siegmund, O. H. W.; Ertley, C.; Vallerga, J. V.; Cremer, T.; Craven, C. A.; Lyashenko, A.; Minot, M. J.

    High time resolution astronomical and remote sensing applications have been addressed with microchannel plate based imaging, photon time tagging detector sealed tube schemes. These are being realized with the advent of cross strip readout techniques with high performance encoding electronics and atomic layer deposited (ALD) microchannel plate technologies. Sealed tube devices up to 20 cm square have now been successfully implemented with sub nanosecond timing and imaging. The objective is to provide sensors with large areas (25 cm2 to 400 cm2) with spatial resolutions of <20 μm FWHM and timing resolutions of <100 ps for dynamic imaging. New high efficiency photocathodes for the visible regime are discussed, which also allow response down below 150nm for UV sensing. Borosilicate MCPs are providing high performance, and when processed with ALD techniques are providing order of magnitude lifetime improvements and enhanced photocathode stability. New developments include UV/visible photocathodes, ALD MCPs, and high resolution cross strip anodes for 100 mm detectors. Tests with 50 mm format cross strip readouts suitable for Planacon devices show spatial resolutions better than 20 μm FWHM, with good image linearity while using low gain ( 106). Current cross strip encoding electronics can accommodate event rates of >5 MHz and event timing accuracy of 100 ps. High-performance ASIC versions of these electronics are in development with better event rate, power and mass suitable for spaceflight instruments.

  7. Monitoring Tamarisk Defoliation and Scaling Evapotranspiration Using Remote Sensing Data

    NASA Astrophysics Data System (ADS)

    Dennison, P. E.; Hultine, K. R.; Nagler, P. L.; Miura, T.; Glenn, E. P.; Ehleringer, J. R.

    2008-12-01

    Non-native tamarisk (Tamarix spp.) has invaded riparian ecosystems throughout the Western United States. Another non-native species, the saltcedar leaf beetle (Diorhabda elongata), has been released in an attempt to control tamarisk infestations. Most efforts directed towards monitoring tamarisk defoliation by Diorhabda have focused on changes in leaf area or sap flux, but these measurements only give a local view of defoliation impacts. We are assessing the ability of remote sensing data for monitoring tamarisk defoliation and measuring resulting changes in evapotranspiration over space and time. Tamarisk defoliation by Diorhabda has taken place during the past two summers along the Colorado River and its tributaries near Moab, Utah. We are using 15 meter spatial resolution Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) and 250 meter spatial resolution Moderate Resolution Imaging Spectrometer (MODIS) data to monitor tamarisk defoliation. An ASTER normalized difference vegetation index (NDVI) time series has revealed large drops in index values associated with loss of leaf area due to defoliation. MODIS data have superior temporal monitoring abilities, but at the sacrifice of much lower spatial resolution. A MODIS enhanced vegetation index time series has revealed that for pixels where the percentage of riparian cover is moderate or high, defoliation is detectable even at 250 meter spatial resolution. We are comparing MODIS vegetation index time series to site measurements of leaf area and sap flux. We are also using an evapotranspiration model to scale potential water savings resulting from the biocontrol of tamarisk.

  8. High-resolution whole-brain DCE-MRI using constrained reconstruction: Prospective clinical evaluation in brain tumor patients

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Guo, Yi, E-mail: yiguo@usc.edu; Zhu, Yinghua; Lingala, Sajan Goud

    Purpose: To clinically evaluate a highly accelerated T1-weighted dynamic contrast-enhanced (DCE) MRI technique that provides high spatial resolution and whole-brain coverage via undersampling and constrained reconstruction with multiple sparsity constraints. Methods: Conventional (rate-2 SENSE) and experimental DCE-MRI (rate-30) scans were performed 20 minutes apart in 15 brain tumor patients. The conventional clinical DCE-MRI had voxel dimensions 0.9 × 1.3 × 7.0 mm{sup 3}, FOV 22 × 22 × 4.2 cm{sup 3}, and the experimental DCE-MRI had voxel dimensions 0.9 × 0.9 × 1.9 mm{sup 3}, and broader coverage 22 × 22 × 19 cm{sup 3}. Temporal resolution was 5 smore » for both protocols. Time-resolved images and blood–brain barrier permeability maps were qualitatively evaluated by two radiologists. Results: The experimental DCE-MRI scans showed no loss of qualitative information in any of the cases, while achieving substantially higher spatial resolution and whole-brain spatial coverage. Average qualitative scores (from 0 to 3) were 2.1 for the experimental scans and 1.1 for the conventional clinical scans. Conclusions: The proposed DCE-MRI approach provides clinically superior image quality with higher spatial resolution and coverage than currently available approaches. These advantages may allow comprehensive permeability mapping in the brain, which is especially valuable in the setting of large lesions or multiple lesions spread throughout the brain.« less

  9. Spatial downscaling of soil prediction models based on weighted generalized additive models in smallholder farm settings.

    PubMed

    Xu, Yiming; Smith, Scot E; Grunwald, Sabine; Abd-Elrahman, Amr; Wani, Suhas P; Nair, Vimala D

    2017-09-11

    Digital soil mapping (DSM) is gaining momentum as a technique to help smallholder farmers secure soil security and food security in developing regions. However, communications of the digital soil mapping information between diverse audiences become problematic due to the inconsistent scale of DSM information. Spatial downscaling can make use of accessible soil information at relatively coarse spatial resolution to provide valuable soil information at relatively fine spatial resolution. The objective of this research was to disaggregate the coarse spatial resolution soil exchangeable potassium (K ex ) and soil total nitrogen (TN) base map into fine spatial resolution soil downscaled map using weighted generalized additive models (GAMs) in two smallholder villages in South India. By incorporating fine spatial resolution spectral indices in the downscaling process, the soil downscaled maps not only conserve the spatial information of coarse spatial resolution soil maps but also depict the spatial details of soil properties at fine spatial resolution. The results of this study demonstrated difference between the fine spatial resolution downscaled maps and fine spatial resolution base maps is smaller than the difference between coarse spatial resolution base maps and fine spatial resolution base maps. The appropriate and economical strategy to promote the DSM technique in smallholder farms is to develop the relatively coarse spatial resolution soil prediction maps or utilize available coarse spatial resolution soil maps at the regional scale and to disaggregate these maps to the fine spatial resolution downscaled soil maps at farm scale.

  10. LFNet: A Novel Bidirectional Recurrent Convolutional Neural Network for Light-Field Image Super-Resolution.

    PubMed

    Wang, Yunlong; Liu, Fei; Zhang, Kunbo; Hou, Guangqi; Sun, Zhenan; Tan, Tieniu

    2018-09-01

    The low spatial resolution of light-field image poses significant difficulties in exploiting its advantage. To mitigate the dependency of accurate depth or disparity information as priors for light-field image super-resolution, we propose an implicitly multi-scale fusion scheme to accumulate contextual information from multiple scales for super-resolution reconstruction. The implicitly multi-scale fusion scheme is then incorporated into bidirectional recurrent convolutional neural network, which aims to iteratively model spatial relations between horizontally or vertically adjacent sub-aperture images of light-field data. Within the network, the recurrent convolutions are modified to be more effective and flexible in modeling the spatial correlations between neighboring views. A horizontal sub-network and a vertical sub-network of the same network structure are ensembled for final outputs via stacked generalization. Experimental results on synthetic and real-world data sets demonstrate that the proposed method outperforms other state-of-the-art methods by a large margin in peak signal-to-noise ratio and gray-scale structural similarity indexes, which also achieves superior quality for human visual systems. Furthermore, the proposed method can enhance the performance of light field applications such as depth estimation.

  11. Peripheral Vasculature: High-Temporal- and High-Spatial-Resolution Three-dimensional Contrast-enhanced MR Angiography1

    PubMed Central

    Haider, Clifton R.; Glockner, James F.; Stanson, Anthony W.; Riederer, Stephen J.

    2009-01-01

    Purpose: To prospectively evaluate the feasibility of performing high-spatial-resolution (1-mm isotropic) time-resolved three-dimensional (3D) contrast material–enhanced magnetic resonance (MR) angiography of the peripheral vasculature with Cartesian acquisition with projection-reconstruction–like sampling (CAPR) and eightfold accelerated two-dimensional (2D) sensitivity encoding (SENSE). Materials and Methods: All studies were approved by the institutional review board and were HIPAA compliant; written informed consent was obtained from all participants. There were 13 volunteers (mean age, 41.9; range, 27–53 years). The CAPR sequence was adapted to provide 1-mm isotropic spatial resolution and a 5-second frame time. Use of different receiver coil element sizes for those placed on the anterior-to-posterior versus left-to-right sides of the field of view reduced signal-to-noise ratio loss due to acceleration. Results from eight volunteers were rated independently by two radiologists according to prominence of artifact, arterial to venous separation, vessel sharpness, continuity of arterial signal intensity in major arteries (anterior and posterior tibial, peroneal), demarcation of origin of major arteries, and overall diagnostic image quality. MR angiographic results in two patients with peripheral vascular disease were compared with their results at computed tomographic angiography. Results: The sequence exhibited no image artifact adversely affecting diagnostic image quality. Temporal resolution was evaluated to be sufficient in all cases, even with known rapid arterial to venous transit. The vessels were graded to have excellent sharpness, continuity, and demarcation of the origins of the major arteries. Distal muscular branches and the communicating and perforating arteries were routinely seen. Excellent diagnostic quality rating was given for 15 (94%) of 16 evaluations. Conclusion: The feasibility of performing high-diagnostic-quality time-resolved 3D contrast-enhanced MR angiography of the peripheral vasculature by using CAPR and eightfold accelerated 2D SENSE has been demonstrated. © RSNA, 2009 Supplemental material: http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.2533081744/-/DC1 PMID:19789238

  12. Nonlinear structured-illumination enhanced temporal focusing multiphoton excitation microscopy with a digital micromirror device

    PubMed Central

    Cheng, Li-Chung; Lien, Chi-Hsiang; Da Sie, Yong; Hu, Yvonne Yuling; Lin, Chun-Yu; Chien, Fan-Ching; Xu, Chris; Dong, Chen Yuan; Chen, Shean-Jen

    2014-01-01

    In this study, the light diffraction of temporal focusing multiphoton excitation microscopy (TFMPEM) and the excitation patterning of nonlinear structured-illumination microscopy (NSIM) can be simultaneously and accurately implemented via a single high-resolution digital micromirror device. The lateral and axial spatial resolutions of the TFMPEM are remarkably improved through the second-order NSIM and projected structured light, respectively. The experimental results demonstrate that the lateral and axial resolutions are enhanced from 397 nm to 168 nm (2.4-fold) and from 2.33 μm to 1.22 μm (1.9-fold), respectively, in full width at the half maximum. Furthermore, a three-dimensionally rendered image of a cytoskeleton cell featuring ~25 nm microtubules is improved, with other microtubules at a distance near the lateral resolution of 168 nm also able to be distinguished. PMID:25136483

  13. Ultrafast and nonlinear surface-enhanced Raman spectroscopy.

    PubMed

    Gruenke, Natalie L; Cardinal, M Fernanda; McAnally, Michael O; Frontiera, Renee R; Schatz, George C; Van Duyne, Richard P

    2016-04-21

    Ultrafast surface-enhanced Raman spectroscopy (SERS) has the potential to study molecular dynamics near plasmonic surfaces to better understand plasmon-mediated chemical reactions such as plasmonically-enhanced photocatalytic or photovoltaic processes. This review discusses the combination of ultrafast Raman spectroscopic techniques with plasmonic substrates for high temporal resolution, high sensitivity, and high spatial resolution vibrational spectroscopy. First, we introduce background information relevant to ultrafast SERS: the mechanisms of surface enhancement in Raman scattering, the characterization of plasmonic materials with ultrafast techniques, and early complementary techniques to study molecule-plasmon interactions. We then discuss recent advances in surface-enhanced Raman spectroscopies with ultrafast pulses with a focus on the study of molecule-plasmon coupling and molecular dynamics with high sensitivity. We also highlight the challenges faced by this field by the potential damage caused by concentrated, highly energetic pulsed fields in plasmonic hotspots, and finally the potential for future ultrafast SERS studies.

  14. Glacier Melt Detection in Complex Terrain Using New AMSR-E Calibrated Enhanced Daily EASE-Grid 2.0 Brightness Temperature (CETB) Earth System Data Record

    NASA Astrophysics Data System (ADS)

    Ramage, J. M.; Brodzik, M. J.; Hardman, M.

    2016-12-01

    Passive microwave (PM) 18 GHz and 36 GHz horizontally- and vertically-polarized brightness temperatures (Tb) channels from the Advanced Microwave Scanning Radiometer for EOS (AMSR-E) have been important sources of information about snow melt status in glacial environments, particularly at high latitudes. PM data are sensitive to the changes in near-surface liquid water that accompany melt onset, melt intensification, and refreezing. Overpasses are frequent enough that in most areas multiple (2-8) observations per day are possible, yielding the potential for determining the dynamic state of the snow pack during transition seasons. AMSR-E Tb data have been used effectively to determine melt onset and melt intensification using daily Tb and diurnal amplitude variation (DAV) thresholds. Due to mixed pixels in historically coarse spatial resolution Tb data, melt analysis has been impractical in ice-marginal zones where pixels may be only fractionally snow/ice covered, and in areas where the glacier is near large bodies of water: even small regions of open water in a pixel severely impact the microwave signal. We use the new enhanced-resolution Calibrated Passive Microwave Daily EASE-Grid 2.0 Brightness Temperature (CETB) Earth System Data Record product's twice daily obserations to test and update existing snow melt algorithms by determining appropriate melt thresholds for both Tb and DAV for the CETB 18 and 36 GHz channels. We use the enhanced resolution data to evaluate melt characteristics along glacier margins and melt transition zones during the melt seasons in locations spanning a wide range of melt scenarios, including the Patagonian Andes, the Alaskan Coast Range, and the Russian High Arctic icecaps. We quantify how improvement of spatial resolution from the original 12.5 - 25 km-scale pixels to the enhanced resolution of 3.125 - 6.25 km improves the ability to evaluate melt timing across boundaries and transition zones in diverse glacial environments.

  15. Monitoring land surface albedo and vegetation dynamics using high spatial and temporal resolution synthetic time series from Landsat and the MODIS BRDF/NBAR/albedo product

    NASA Astrophysics Data System (ADS)

    Wang, Zhuosen; Schaaf, Crystal B.; Sun, Qingsong; Kim, JiHyun; Erb, Angela M.; Gao, Feng; Román, Miguel O.; Yang, Yun; Petroy, Shelley; Taylor, Jeffrey R.; Masek, Jeffrey G.; Morisette, Jeffrey T.; Zhang, Xiaoyang; Papuga, Shirley A.

    2017-07-01

    Seasonal vegetation phenology can significantly alter surface albedo which in turn affects the global energy balance and the albedo warming/cooling feedbacks that impact climate change. To monitor and quantify the surface dynamics of heterogeneous landscapes, high temporal and spatial resolution synthetic time series of albedo and the enhanced vegetation index (EVI) were generated from the 500 m Moderate Resolution Imaging Spectroradiometer (MODIS) operational Collection V006 daily BRDF/NBAR/albedo products and 30 m Landsat 5 albedo and near-nadir reflectance data through the use of the Spatial and Temporal Adaptive Reflectance Fusion Model (STARFM). The traditional Landsat Albedo (Shuai et al., 2011) makes use of the MODIS BRDF/Albedo products (MCD43) by assigning appropriate BRDFs from coincident MODIS products to each Landsat image to generate a 30 m Landsat albedo product for that acquisition date. The available cloud free Landsat 5 albedos (due to clouds, generated every 16 days at best) were used in conjunction with the daily MODIS albedos to determine the appropriate 30 m albedos for the intervening daily time steps in this study. These enhanced daily 30 m spatial resolution synthetic time series were then used to track albedo and vegetation phenology dynamics over three Ameriflux tower sites (Harvard Forest in 2007, Santa Rita in 2011 and Walker Branch in 2005). These Ameriflux sites were chosen as they are all quite nearby new towers coming on line for the National Ecological Observatory Network (NEON), and thus represent locations which will be served by spatially paired albedo measures in the near future. The availability of data from the NEON towers will greatly expand the sources of tower albedometer data available for evaluation of satellite products. At these three Ameriflux tower sites the synthetic time series of broadband shortwave albedos were evaluated using the tower albedo measurements with a Root Mean Square Error (RMSE) less than 0.013 and a bias within the range of ±0.006. These synthetic time series provide much greater spatial detail than the 500 m gridded MODIS data, especially over more heterogeneous surfaces, which improves the efforts to characterize and monitor the spatial variation across species and communities. The mean of the difference between maximum and minimum synthetic time series of albedo within the MODIS pixels over a subset of satellite data of Harvard Forest (16 km by 14 km) was as high as 0.2 during the snow-covered period and reduced to around 0.1 during the snow-free period. Similarly, we have used STARFM to also couple MODIS Nadir BRDF Adjusted Reflectances (NBAR) values with Landsat 5 reflectances to generate daily synthetic times series of NBAR and thus Enhanced Vegetation Index (NBAR-EVI) at a 30 m resolution. While normally STARFM is used with directional reflectances, the use of the view angle corrected daily MODIS NBAR values will provide more consistent time series. These synthetic times series of EVI are shown to capture seasonal vegetation dynamics with finer spatial and temporal details, especially over heterogeneous land surfaces.

  16. Monitoring land surface albedo and vegetation dynamics using high spatial and temporal resolution synthetic time series from Landsat and the MODIS BRDF/NBAR/albedo product

    USGS Publications Warehouse

    Wang, Zhuosen; Schaaf, Crystal B.; Sun, Qingson; Kim, JiHyun; Erb, Angela M.; Gao, Feng; Roman, Miguel O.; Yang, Yun; Petroy, Shelley; Taylor, Jeffrey; Masek, Jeffrey G.; Morisette, Jeffrey T.; Zhang, Xiaoyang; Papuga, Shirley A.

    2017-01-01

    Seasonal vegetation phenology can significantly alter surface albedo which in turn affects the global energy balance and the albedo warming/cooling feedbacks that impact climate change. To monitor and quantify the surface dynamics of heterogeneous landscapes, high temporal and spatial resolution synthetic time series of albedo and the enhanced vegetation index (EVI) were generated from the 500 m Moderate Resolution Imaging Spectroradiometer (MODIS) operational Collection V006 daily BRDF/NBAR/albedo products and 30 m Landsat 5 albedo and near-nadir reflectance data through the use of the Spatial and Temporal Adaptive Reflectance Fusion Model (STARFM). The traditional Landsat Albedo (Shuai et al., 2011) makes use of the MODIS BRDF/Albedo products (MCD43) by assigning appropriate BRDFs from coincident MODIS products to each Landsat image to generate a 30 m Landsat albedo product for that acquisition date. The available cloud free Landsat 5 albedos (due to clouds, generated every 16 days at best) were used in conjunction with the daily MODIS albedos to determine the appropriate 30 m albedos for the intervening daily time steps in this study. These enhanced daily 30 m spatial resolution synthetic time series were then used to track albedo and vegetation phenology dynamics over three Ameriflux tower sites (Harvard Forest in 2007, Santa Rita in 2011 and Walker Branch in 2005). These Ameriflux sites were chosen as they are all quite nearby new towers coming on line for the National Ecological Observatory Network (NEON), and thus represent locations which will be served by spatially paired albedo measures in the near future. The availability of data from the NEON towers will greatly expand the sources of tower albedometer data available for evaluation of satellite products. At these three Ameriflux tower sites the synthetic time series of broadband shortwave albedos were evaluated using the tower albedo measurements with a Root Mean Square Error (RMSE) less than 0.013 and a bias within the range of ±0.006. These synthetic time series provide much greater spatial detail than the 500 m gridded MODIS data, especially over more heterogeneous surfaces, which improves the efforts to characterize and monitor the spatial variation across species and communities. The mean of the difference between maximum and minimum synthetic time series of albedo within the MODIS pixels over a subset of satellite data of Harvard Forest (16 km by 14 km) was as high as 0.2 during the snow-covered period and reduced to around 0.1 during the snow-free period. Similarly, we have used STARFM to also couple MODIS Nadir BRDF Adjusted Reflectances (NBAR) values with Landsat 5 reflectances to generate daily synthetic times series of NBAR and thus Enhanced Vegetation Index (NBAR-EVI) at a 30 m resolution. While normally STARFM is used with directional reflectances, the use of the view angle corrected daily MODIS NBAR values will provide more consistent time series. These synthetic times series of EVI are shown to capture seasonal vegetation dynamics with finer spatial and temporal details, especially over heterogeneous land surfaces.

  17. Monitoring Land Surface Albedo and Vegetation Dynamics Using High Spatial and Temporal Resolution Synthetic Time Series from Landsat and the MODIS BRDF/NBAR/Albedo Product

    NASA Technical Reports Server (NTRS)

    Wang, Zhuosen; Schaaf, Crystal B.; Sun, Quingsong; Kim, Jihyun; Erb, Angela M.; Gao, Feng; Roman, Miguel O.; Yang, Yun; Petroy, Shelley; Taylor, Jeffrey R.; hide

    2017-01-01

    Seasonal vegetation phenology can significantly alter surface albedo which in turn affects the global energy balance and the albedo warmingcooling feedbacks that impact climate change. To monitor and quantify the surface dynamics of heterogeneous landscapes, high temporal and spatial resolution synthetic time series of albedo and the enhanced vegetation index (EVI) were generated from the 500-meter Moderate Resolution Imaging Spectroradiometer (MODIS) operational Collection V006 daily BRDF (Bidirectional Reflectance Distribution Function) / NBAR (Nadir BRDF-Adjusted Reflectance) / albedo products and 30-meter Landsat 5 albedo and near-nadir reflectance data through the use of the Spatial and Temporal Adaptive Reflectance Fusion Model (STARFM). The traditional Landsat Albedo (Shuai et al., 2011) makes use of the MODIS BRDFAlbedo products (MCD43) by assigning appropriate BRDFs from coincident MODIS products to each Landsat image to generate a 30-meter Landsat albedo product for that acquisition date. The available cloud free Landsat 5 albedos (due to clouds, generated every 16 days at best) were used in conjunction with the daily MODIS albedos to determine the appropriate 30-meter albedos for the intervening daily time steps in this study. These enhanced daily 30-meter spatial resolution synthetic time series were then used to track albedo and vegetation phenology dynamics over three Ameriflux tower sites (Harvard Forest in 2007, Santa Rita in 2011 and Walker Branch in 2005). These Ameriflux sites were chosen as they are all quite nearby new towers coming on line for the National Ecological Observatory Network (NEON), and thus represent locations which will be served by spatially paired albedo measures in the near future. The availability of data from the NEON towers will greatly expand the sources of tower albedometer data available for evaluation of satellite products. At these three Ameriflux tower sites the synthetic time series of broadband shortwave albedos were evaluated using the tower albedo measurements with a Root Mean Square Error (RMSE) less than 0.013 and a bias within the range of 0.006. These synthetic time series provide much greater spatial detail than the 500 meter gridded MODIS data, especially over more heterogeneous surfaces, which improves the efforts to characterize and monitor the spatial variation across species and communities. The mean of the difference between maximum and minimum synthetic time series of albedo within the MODIS pixels over a subset of satellite data of Harvard Forest (16 kilometers by 14 kilometers) was as high as 0.2 during the snow-covered period and reduced to around 0.1 during the snow-free period. Similarly, we have used STARFM to also couple MODIS Nadir BRDF-Adjusted Reflectances (NBAR) values with Landsat 5 reflectances to generate daily synthetic times series of NBAR and thus Enhanced Vegetation Index (NBAR-EVI) at a 30-meter resolution. While normally STARFM is used with directional reflectances, the use of the view angle corrected daily MODIS NBAR values will provide more consistent time series. These synthetic times series of EVI are shown to capture seasonal vegetation dynamics with finer spatial and temporal details, especially over heterogeneous land surfaces.

  18. FIMic: design for ultimate 3D-integral microscopy of in-vivo biological samples

    PubMed Central

    Scrofani, G.; Sola-Pikabea, J.; Llavador, A.; Sanchez-Ortiga, E.; Barreiro, J. C.; Saavedra, G.; Garcia-Sucerquia, J.; Martínez-Corral, M.

    2017-01-01

    In this work, Fourier integral microscope (FIMic), an ultimate design of 3D-integral microscopy, is presented. By placing a multiplexing microlens array at the aperture stop of the microscope objective of the host microscope, FIMic shows extended depth of field and enhanced lateral resolution in comparison with regular integral microscopy. As FIMic directly produces a set of orthographic views of the 3D-micrometer-sized sample, it is suitable for real-time imaging. Following regular integral-imaging reconstruction algorithms, a 2.75-fold enhanced depth of field and 2-time better spatial resolution in comparison with conventional integral microscopy is reported. Our claims are supported by theoretical analysis and experimental images of a resolution test target, cotton fibers, and in-vivo 3D-imaging of biological specimens. PMID:29359107

  19. High-resolution MRI vessel wall imaging: spatial and temporal patterns of reversible cerebral vasoconstriction syndrome and central nervous system vasculitis.

    PubMed

    Obusez, E C; Hui, F; Hajj-Ali, R A; Cerejo, R; Calabrese, L H; Hammad, T; Jones, S E

    2014-08-01

    High-resolution MR imaging is an emerging tool for evaluating intracranial artery disease. It has an advantage of defining vessel wall characteristics of intracranial vascular diseases. We investigated high-resolution MR imaging arterial wall characteristics of CNS vasculitis and reversible cerebral vasoconstriction syndrome to determine wall pattern changes during a follow-up period. We retrospectively reviewed 3T-high-resolution MR imaging vessel wall studies performed on 26 patients with a confirmed diagnosis of CNS vasculitis and reversible cerebral vasoconstriction syndrome during a follow-up period. Vessel wall imaging protocol included black-blood contrast-enhanced T1-weighted sequences with fat suppression and a saturation band, and time-of-flight MRA of the circle of Willis. Vessel wall characteristics including enhancement, wall thickening, and lumen narrowing were collected. Thirteen patients with CNS vasculitis and 13 patients with reversible cerebral vasoconstriction syndrome were included. In the CNS vasculitis group, 9 patients showed smooth, concentric wall enhancement and thickening; 3 patients had smooth, eccentric wall enhancement and thickening; and 1 patient was without wall enhancement and thickening. Six of 13 patients had follow-up imaging; 4 patients showed stable smooth, concentric enhancement and thickening; and 2 patients had resoluton of initial imaging findings. In the reversible cerebral vasoconstriction syndrome group, 10 patients showed diffuse, uniform wall thickening with negligible-to-mild enhancement. Nine patients had follow-up imaging, with 8 patients showing complete resolution of the initial findings. Postgadolinium 3T-high-resolution MR imaging appears to be a feasible tool in differentiating vessel wall patterns of CNS vasculitis and reversible cerebral vasoconstriction syndrome changes during a follow-up period. © 2014 by American Journal of Neuroradiology.

  20. High resolution satellite observations of mesoscale oceanography in the Tasman Sea, 1978 - 1979

    NASA Technical Reports Server (NTRS)

    Nilsson, C. S.; Andrews, J. C.; Hornibrook, M.; Latham, A. R.; Speechley, G. C.; Scully-Power, P. (Principal Investigator)

    1982-01-01

    Of the Nearly 1000 standard infrared photographic images received, 273 images were on computer compatible tape. It proved necessary to digitally enhance the scene contrast to cover only a select few degrees K over the photographic grey scale appropriate to the scene-specific range of sea surface temperature (SST). Some 178 images were so enhanced. Comparison with sea truth show that SST, as seen by satellite, provides a good guide to the ocean currents and eddies off East Australia, both in summer and winter. This is in contrast, particularly in summer, to SST mapped by surface survey, which usually lacks the necessary spatial resolution.

  1. Reserch on Spatial and Temporal Distribution of Color Steel Building Based on Multi-Source High-Resolution Satellite Imagery

    NASA Astrophysics Data System (ADS)

    Yang, S. W.; Ma, J. J.; Wang, J. M.

    2018-04-01

    As representative vulnerable regions of the city, dense distribution areas of temporary color steel building are a major target for control of fire risks, illegal buildings, environmental supervision, urbanization quality and enhancement for city's image. In the domestic and foreign literature, the related research mainly focuses on fire risks and violation monitoring. However, due to temporary color steel building's special characteristics, the corresponding research about temporal and spatial distribution, and influence on urban spatial form etc. has not been reported. Therefore, firstly, the paper research aim plans to extract information of large-scale color steel building from high-resolution images. Secondly, the color steel plate buildings were classified, and the spatial and temporal distribution and aggregation characteristics of small (temporary buildings) and large (factory building, warehouse, etc.) buildings were studied respectively. Thirdly, the coupling relationship between the spatial distribution of color steel plate and the spatial pattern of urban space was analysed. The results show that there is a good coupling relationship between the color steel plate building and the urban spatial form. Different types of color steel plate building represent the pattern of regional differentiation of urban space and the phased pattern of urban development.

  2. An evaluation of the potential of Sentinel 1 for improving flash flood predictions via soil moisture-data assimilation

    NASA Astrophysics Data System (ADS)

    Cenci, Luca; Pulvirenti, Luca; Boni, Giorgio; Chini, Marco; Matgen, Patrick; Gabellani, Simone; Squicciarino, Giuseppe; Pierdicca, Nazzareno

    2017-11-01

    The assimilation of satellite-derived soil moisture estimates (soil moisture-data assimilation, SM-DA) into hydrological models has the potential to reduce the uncertainty of streamflow simulations. The improved capacity to monitor the closeness to saturation of small catchments, such as those characterizing the Mediterranean region, can be exploited to enhance flash flood predictions. When compared to other microwave sensors that have been exploited for SM-DA in recent years (e.g. the Advanced SCATterometer - ASCAT), characterized by low spatial/high temporal resolution, the Sentinel 1 (S1) mission provides an excellent opportunity to monitor systematically soil moisture (SM) at high spatial resolution and moderate temporal resolution. The aim of this research was thus to evaluate the impact of S1-based SM-DA for enhancing flash flood predictions of a hydrological model (Continuum) that is currently exploited for civil protection applications in Italy. The analysis was carried out in a representative Mediterranean catchment prone to flash floods, located in north-western Italy, during the time period October 2014-February 2015. It provided some important findings: (i) revealing the potential provided by S1-based SM-DA for improving discharge predictions, especially for higher flows; (ii) suggesting a more appropriate pre-processing technique to be applied to S1 data before the assimilation; and (iii) highlighting that even though high spatial resolution does provide an important contribution in a SM-DA system, the temporal resolution has the most crucial role. S1-derived SM maps are still a relatively new product and, to our knowledge, this is the first work published in an international journal dealing with their assimilation within a hydrological model to improve continuous streamflow simulations and flash flood predictions. Even though the reported results were obtained by analysing a relatively short time period, and thus should be supported by further research activities, we believe this research is timely in order to enhance our understanding of the potential contribution of the S1 data within the SM-DA framework for flash flood risk mitigation.

  3. Increased-resolution OCT thickness mapping of the human macula: a statistically based registration.

    PubMed

    Bernardes, Rui; Santos, Torcato; Cunha-Vaz, José

    2008-05-01

    To describe the development of a technique that enhances spatial resolution of retinal thickness maps of the Stratus OCT (Carl Zeiss Meditec, Inc., Dublin, CA). A retinal thickness atlas (RT-atlas) template was calculated, and a macular coordinate system was established, to pursue this objective. The RT-atlas was developed from principal component analysis of retinal thickness analyzer (RTA) maps acquired from healthy volunteers. The Stratus OCT radial thickness measurements were registered on the RT-atlas, from which an improved macular thickness map was calculated. Thereafter, Stratus OCT circular scans were registered on the previously calculated map to enhance spatial resolution. The developed technique was applied to Stratus OCT thickness data from healthy volunteers and from patients with diabetic retinopathy (DR) or age-related macular degeneration (AMD). Results showed that for normal, or close to normal, macular thickness maps from healthy volunteers and patients with DR, this technique can be an important aid in determining retinal thickness. Efforts are under way to improve the registration of retinal thickness data in patients with AMD. The developed technique enhances the evaluation of data acquired by the Stratus OCT, helping the detection of early retinal thickness abnormalities. Moreover, a normative database of retinal thickness measurements gained from this technique, as referenced to the macular coordinate system, can be created without errors induced by missed fixation and eye tilt.

  4. Cerebral TOF Angiography at 7T: Impact of B1+ Shimming with a 16-Channel Transceiver Array

    PubMed Central

    Schmitter, Sebastian; Wu, Xiaoping; Adriany, Gregor; Auerbach, Edward J.; Uğurbil, Kâmil; Van de Moortele, Pierre-François

    2014-01-01

    Purpose Time-of-flight (TOF) MR imaging is clinically among the most common cerebral non-contrast enhanced MR angiography techniques allowing for high spatial resolution. As shown by several groups TOF contrast significantly improves at ultra-high field (UHF) of B0=7T, however, spatially varying transmit B1 (B1+) fields at 7T reduce TOF contrast uniformity, typically resulting in sub-optimal contrast and reduced vessel conspicuity in the brain periphery. Methods Using a 16-channel B1+ shimming system we compare different dynamically applied B1+ phase shimming approaches on the RF excitation to improve contrast homogeneity for a (0.5 mm)3 resolution multi-slab TOF acquisition. In addition, B1+ shimming applied on the venous saturation pulse was investigated to improve venous suppression, subcutaneous fat signal reduction and enhanced background suppression originating from MT effect. Results B1+ excitation homogeneity was improved by a factor 2.2 to 2.6 on average depending on the shimming approach, compared to a standard CP-like phase setting, leading to improved vessel conspicuity particularly in the periphery. Stronger saturation, higher fat suppression and improved background suppression were observed when dynamically applying B1+ shimming on the venous saturation pulse. Conclusion B1+ shimming can significantly improve high resolution TOF vascular investigations at UHF, holding strong promise for non contrast-enhanced clinical applications. PMID:23640915

  5. Surface plasmon enhanced cell microscopy with blocked random spatial activation

    NASA Astrophysics Data System (ADS)

    Son, Taehwang; Oh, Youngjin; Lee, Wonju; Yang, Heejin; Kim, Donghyun

    2016-03-01

    We present surface plasmon enhanced fluorescence microscopy with random spatial sampling using patterned block of silver nanoislands. Rigorous coupled wave analysis was performed to confirm near-field localization on nanoislands. Random nanoislands were fabricated in silver by temperature annealing. By analyzing random near-field distribution, average size of localized fields was found to be on the order of 135 nm. Randomly localized near-fields were used to spatially sample F-actin of J774 cells (mouse macrophage cell-line). Image deconvolution algorithm based on linear imaging theory was established for stochastic estimation of fluorescent molecular distribution. The alignment between near-field distribution and raw image was performed by the patterned block. The achieved resolution is dependent upon factors including the size of localized fields and estimated to be 100-150 nm.

  6. Tip-enhanced near-field optical microscope with side-on and ATR-mode sample excitation for super-resolution Raman imaging of surfaces

    NASA Astrophysics Data System (ADS)

    Heilman, A. L.; Gordon, M. J.

    2016-06-01

    A tip-enhanced near-field optical microscope with side-on and attenuated total reflectance (ATR) excitation and collection is described and used to demonstrate sub-diffraction-limited (super-resolution) optical and chemical characterization of surfaces. ATR illumination is combined with an Au optical antenna tip to show that (i) the tip can quantitatively transduce the optical near-field (evanescent waves) above the surface by scattering photons into the far-field, (ii) the ATR geometry enables excitation and characterization of surface plasmon polaritons (SPPs), whose associated optical fields are shown to enhance Raman scattering from a thin layer of copper phthalocyanine (CuPc), and (iii) SPPs can be used to plasmonically excite the tip for super-resolution chemical imaging of patterned CuPc via tip-enhanced Raman spectroscopy (TERS). ATR-illumination TERS is also quantitatively compared with the more conventional side-on illumination scheme. In both cases, spatial resolution was better than 40 nm and tip on/tip off Raman enhancement factors were >6500. Furthermore, ATR illumination was shown to provide similar Raman signal levels at lower "effective" pump powers due to additional optical energy delivered by SPPs to the active region in the tip-surface gap.

  7. Tip-enhanced near-field optical microscope with side-on and ATR-mode sample excitation for super-resolution Raman imaging of surfaces

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Heilman, A. L.; Gordon, M. J.

    A tip-enhanced near-field optical microscope with side-on and attenuated total reflectance (ATR) excitation and collection is described and used to demonstrate sub-diffraction-limited (super-resolution) optical and chemical characterization of surfaces. ATR illumination is combined with an Au optical antenna tip to show that (i) the tip can quantitatively transduce the optical near-field (evanescent waves) above the surface by scattering photons into the far-field, (ii) the ATR geometry enables excitation and characterization of surface plasmon polaritons (SPPs), whose associated optical fields are shown to enhance Raman scattering from a thin layer of copper phthalocyanine (CuPc), and (iii) SPPs can be used tomore » plasmonically excite the tip for super-resolution chemical imaging of patterned CuPc via tip-enhanced Raman spectroscopy (TERS). ATR-illumination TERS is also quantitatively compared with the more conventional side-on illumination scheme. In both cases, spatial resolution was better than 40 nm and tip on/tip off Raman enhancement factors were >6500. Furthermore, ATR illumination was shown to provide similar Raman signal levels at lower “effective” pump powers due to additional optical energy delivered by SPPs to the active region in the tip-surface gap.« less

  8. SU-E-I-82: Improving CT Image Quality for Radiation Therapy Using Iterative Reconstruction Algorithms and Slightly Increasing Imaging Doses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Noid, G; Chen, G; Tai, A

    2014-06-01

    Purpose: Iterative reconstruction (IR) algorithms are developed to improve CT image quality (IQ) by reducing noise without diminishing spatial resolution or contrast. For CT in radiation therapy (RT), slightly increasing imaging dose to improve IQ may be justified if it can substantially enhance structure delineation. The purpose of this study is to investigate and to quantify the IQ enhancement as a result of increasing imaging doses and using IR algorithms. Methods: CT images were acquired for phantoms, built to evaluate IQ metrics including spatial resolution, contrast and noise, with a variety of imaging protocols using a CT scanner (Definition ASmore » Open, Siemens) installed inside a Linac room. Representative patients were scanned once the protocols were optimized. Both phantom and patient scans were reconstructed using the Sinogram Affirmed Iterative Reconstruction (SAFIRE) and the Filtered Back Projection (FBP) methods. IQ metrics of the obtained CTs were compared. Results: IR techniques are demonstrated to preserve spatial resolution as measured by the point spread function and reduce noise in comparison to traditional FBP. Driven by the reduction in noise, the contrast to noise ratio is doubled by adopting the highest SAFIRE strength. As expected, increasing imaging dose reduces noise for both SAFIRE and FBP reconstructions. The contrast to noise increases from 3 to 5 by increasing the dose by a factor of 4. Similar IQ improvement was observed on the CTs for selected patients with pancreas and prostrate cancers. Conclusion: The IR techniques produce a measurable enhancement to CT IQ by reducing the noise. Increasing imaging dose further reduces noise independent of the IR techniques. The improved CT enables more accurate delineation of tumors and/or organs at risk during RT planning and delivery guidance.« less

  9. Comparison of diffraction-enhanced computed tomography and monochromatic synchrotron radiation computed tomography of human trabecular bone.

    PubMed

    Connor, D M; Hallen, H D; Lalush, D S; Sumner, D R; Zhong, Z

    2009-10-21

    Diffraction-enhanced imaging (DEI) is an x-ray-based medical imaging modality that, when used in tomography mode (DECT), can generate a three-dimensional map of both the apparent absorption coefficient and the out-of-plane gradient of the index of refraction of the sample. DECT is known to have contrast gains over monochromatic synchrotron radiation CT (SRCT) for soft tissue structures. The goal of this experiment was to compare contrast-to-noise ratio (CNR) and resolution in images of human trabecular bone acquired using SRCT with images acquired using DECT. All images were acquired at the National Synchrotron Light Source (Upton, NY, USA) at beamline X15 A at an x-ray energy of 40 keV and the silicon [3 3 3] reflection. SRCT, apparent absorption DECT and refraction DECT slice images of the trabecular bone were created. The apparent absorption DECT images have significantly higher spatial resolution and CNR than the corresponding SRCT images. Thus, DECT will prove to be a useful tool for imaging applications in which high contrast and high spatial resolution are required for both soft tissue features and bone.

  10. Design analysis of an MPI human functional brain scanner

    PubMed Central

    Mason, Erica E.; Cooley, Clarissa Z.; Cauley, Stephen F.; Griswold, Mark A.; Conolly, Steven M.; Wald, Lawrence L.

    2017-01-01

    MPI’s high sensitivity makes it a promising modality for imaging brain function. Functional contrast is proposed based on blood SPION concentration changes due to Cerebral Blood Volume (CBV) increases during activation, a mechanism utilized in fMRI studies. MPI offers the potential for a direct and more sensitive measure of SPION concentration, and thus CBV, than fMRI. As such, fMPI could surpass fMRI in sensitivity, enhancing the scientific and clinical value of functional imaging. As human-sized MPI systems have not been attempted, we assess the technical challenges of scaling MPI from rodent to human brain. We use a full-system MPI simulator to test arbitrary hardware designs and encoding practices, and we examine tradeoffs imposed by constraints that arise when scaling to human size as well as safety constraints (PNS and central nervous system stimulation) not considered in animal scanners, thereby estimating spatial resolutions and sensitivities achievable with current technology. Using a projection FFL MPI system, we examine coil hardware options and their implications for sensitivity and spatial resolution. We estimate that an fMPI brain scanner is feasible, although with reduced sensitivity (20×) and spatial resolution (5×) compared to existing rodent systems. Nonetheless, it retains sufficient sensitivity and spatial resolution to make it an attractive future instrument for studying the human brain; additional technical innovations can result in further improvements. PMID:28752130

  11. An atlas of high-resolution IRAS maps on nearby galaxies

    NASA Technical Reports Server (NTRS)

    Rice, Walter

    1993-01-01

    An atlas of far-infrared IRAS maps with near 1 arcmin angular resolution of 30 optically large galaxies is presented. The high-resolution IRAS maps were produced with the Maximum Correlation Method (MCM) image construction and enhancement technique developed at IPAC. The MCM technique, which recovers the spatial information contained in the overlapping detector data samples of the IRAS all-sky survey scans, is outlined and tests to verify the structural reliability and photometric integrity of the high-resolution maps are presented. The infrared structure revealed in individual galaxies is discussed. The atlas complements the IRAS Nearby Galaxy High-Resolution Image Atlas, the high-resolution galaxy images encoded in FITS format, which is provided to the astronomical community as an IPAC product.

  12. Accelerated high-resolution photoacoustic tomography via compressed sensing

    NASA Astrophysics Data System (ADS)

    Arridge, Simon; Beard, Paul; Betcke, Marta; Cox, Ben; Huynh, Nam; Lucka, Felix; Ogunlade, Olumide; Zhang, Edward

    2016-12-01

    Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in living tissue (4D PAT). A particular example is the planar Fabry-Pérot (FP) photoacoustic scanner, which yields high-resolution 3D images but takes several minutes to sequentially map the incident photoacoustic field on the 2D sensor plane, point-by-point. However, as the spatio-temporal complexity of many absorbing tissue structures is rather low, the data recorded in such a conventional, regularly sampled fashion is often highly redundant. We demonstrate that combining model-based, variational image reconstruction methods using spatial sparsity constraints with the development of novel PAT acquisition systems capable of sub-sampling the acoustic wave field can dramatically increase the acquisition speed while maintaining a good spatial resolution: first, we describe and model two general spatial sub-sampling schemes. Then, we discuss how to implement them using the FP interferometer and demonstrate the potential of these novel compressed sensing PAT devices through simulated data from a realistic numerical phantom and through measured data from a dynamic experimental phantom as well as from in vivo experiments. Our results show that images with good spatial resolution and contrast can be obtained from highly sub-sampled PAT data if variational image reconstruction techniques that describe the tissues structures with suitable sparsity-constraints are used. In particular, we examine the use of total variation (TV) regularization enhanced by Bregman iterations. These novel reconstruction strategies offer new opportunities to dramatically increase the acquisition speed of photoacoustic scanners that employ point-by-point sequential scanning as well as reducing the channel count of parallelized schemes that use detector arrays.

  13. Single-pulse enhanced coherent diffraction imaging of bacteria with an X-ray free-electron laser

    NASA Astrophysics Data System (ADS)

    Fan, Jiadong; Sun, Zhibin; Wang, Yaling; Park, Jaehyun; Kim, Sunam; Gallagher-Jones, Marcus; Kim, Yoonhee; Song, Changyong; Yao, Shengkun; Zhang, Jian; Zhang, Jianhua; Duan, Xiulan; Tono, Kensuke; Yabashi, Makina; Ishikawa, Tetsuya; Fan, Chunhai; Zhao, Yuliang; Chai, Zhifang; Gao, Xueyun; Earnest, Thomas; Jiang, Huaidong

    2016-09-01

    High-resolution imaging offers one of the most promising approaches for exploring and understanding the structure and function of biomaterials and biological systems. X-ray free-electron lasers (XFELs) combined with coherent diffraction imaging can theoretically provide high-resolution spatial information regarding biological materials using a single XFEL pulse. Currently, the application of this method suffers from the low scattering cross-section of biomaterials and X-ray damage to the sample. However, XFELs can provide pulses of such short duration that the data can be collected using the “diffract and destroy” approach before the effects of radiation damage on the data become significant. These experiments combine the use of enhanced coherent diffraction imaging with single-shot XFEL radiation to investigate the cellular architecture of Staphylococcus aureus with and without labeling by gold (Au) nanoclusters. The resolution of the images reconstructed from these diffraction patterns were twice as high or more for gold-labeled samples, demonstrating that this enhancement method provides a promising approach for the high-resolution imaging of biomaterials and biological systems.

  14. Single-pulse enhanced coherent diffraction imaging of bacteria with an X-ray free-electron laser

    PubMed Central

    Fan, Jiadong; Sun, Zhibin; Wang, Yaling; Park, Jaehyun; Kim, Sunam; Gallagher-Jones, Marcus; Kim, Yoonhee; Song, Changyong; Yao, Shengkun; Zhang, Jian; Zhang, Jianhua; Duan, Xiulan; Tono, Kensuke; Yabashi, Makina; Ishikawa, Tetsuya; Fan, Chunhai; Zhao, Yuliang; Chai, Zhifang; Gao, Xueyun; Earnest, Thomas; Jiang, Huaidong

    2016-01-01

    High-resolution imaging offers one of the most promising approaches for exploring and understanding the structure and function of biomaterials and biological systems. X-ray free-electron lasers (XFELs) combined with coherent diffraction imaging can theoretically provide high-resolution spatial information regarding biological materials using a single XFEL pulse. Currently, the application of this method suffers from the low scattering cross-section of biomaterials and X-ray damage to the sample. However, XFELs can provide pulses of such short duration that the data can be collected using the “diffract and destroy” approach before the effects of radiation damage on the data become significant. These experiments combine the use of enhanced coherent diffraction imaging with single-shot XFEL radiation to investigate the cellular architecture of Staphylococcus aureus with and without labeling by gold (Au) nanoclusters. The resolution of the images reconstructed from these diffraction patterns were twice as high or more for gold-labeled samples, demonstrating that this enhancement method provides a promising approach for the high-resolution imaging of biomaterials and biological systems. PMID:27659203

  15. Single-pulse enhanced coherent diffraction imaging of bacteria with an X-ray free-electron laser.

    PubMed

    Fan, Jiadong; Sun, Zhibin; Wang, Yaling; Park, Jaehyun; Kim, Sunam; Gallagher-Jones, Marcus; Kim, Yoonhee; Song, Changyong; Yao, Shengkun; Zhang, Jian; Zhang, Jianhua; Duan, Xiulan; Tono, Kensuke; Yabashi, Makina; Ishikawa, Tetsuya; Fan, Chunhai; Zhao, Yuliang; Chai, Zhifang; Gao, Xueyun; Earnest, Thomas; Jiang, Huaidong

    2016-09-23

    High-resolution imaging offers one of the most promising approaches for exploring and understanding the structure and function of biomaterials and biological systems. X-ray free-electron lasers (XFELs) combined with coherent diffraction imaging can theoretically provide high-resolution spatial information regarding biological materials using a single XFEL pulse. Currently, the application of this method suffers from the low scattering cross-section of biomaterials and X-ray damage to the sample. However, XFELs can provide pulses of such short duration that the data can be collected using the "diffract and destroy" approach before the effects of radiation damage on the data become significant. These experiments combine the use of enhanced coherent diffraction imaging with single-shot XFEL radiation to investigate the cellular architecture of Staphylococcus aureus with and without labeling by gold (Au) nanoclusters. The resolution of the images reconstructed from these diffraction patterns were twice as high or more for gold-labeled samples, demonstrating that this enhancement method provides a promising approach for the high-resolution imaging of biomaterials and biological systems.

  16. Enhancing sensitivity of high resolution optical coherence tomography using an optional spectrally encoded extended source (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Yu, Xiaojun; Liu, Xinyu; Chen, Si; Wang, Xianghong; Liu, Linbo

    2016-03-01

    High-resolution optical coherence tomography (OCT) is of critical importance to disease diagnosis because it is capable of providing detailed microstructural information of the biological tissues. However, a compromise usually has to be made between its spatial resolutions and sensitivity due to the suboptimal spectral response of the system components, such as the linear camera, the dispersion grating, and the focusing lenses, etc. In this study, we demonstrate an OCT system that achieves both high spatial resolutions and enhanced sensitivity through utilizing a spectrally encoded source. The system achieves a lateral resolution of 3.1 μm and an axial resolution of 2.3 μm in air; when with a simple dispersive prism placed in the infinity space of the sample arm optics, the illumination beam on the sample is transformed into a line source with a visual angle of 10.3 mrad. Such an extended source technique allows a ~4 times larger maximum permissible exposure (MPE) than its point source counterpart, which thus improves the system sensitivity by ~6dB. In addition, the dispersive prism can be conveniently switched to a reflector. Such flexibility helps increase the penetration depth of the system without increasing the complexity of the current point source devices. We conducted experiments to characterize the system's imaging capability using the human fingertip in vivo and the swine eye optic never disc ex vivo. The higher penetration depth of such a system over the conventional point source OCT system is also demonstrated in these two tissues.

  17. High-throughput isotropic mapping of whole mouse brain using multi-view light-sheet microscopy

    NASA Astrophysics Data System (ADS)

    Nie, Jun; Li, Yusha; Zhao, Fang; Ping, Junyu; Liu, Sa; Yu, Tingting; Zhu, Dan; Fei, Peng

    2018-02-01

    Light-sheet fluorescence microscopy (LSFM) uses an additional laser-sheet to illuminate selective planes of the sample, thereby enabling three-dimensional imaging at high spatial-temporal resolution. These advantages make LSFM a promising tool for high-quality brain visualization. However, even by the use of LSFM, the spatial resolution remains insufficient to resolve the neural structures across a mesoscale whole mouse brain in three dimensions. At the same time, the thick-tissue scattering prevents a clear observation from the deep of brain. Here we use multi-view LSFM strategy to solve this challenge, surpassing the resolution limit of standard light-sheet microscope under a large field-of-view (FOV). As demonstrated by the imaging of optically-cleared mouse brain labelled with thy1-GFP, we achieve a brain-wide, isotropic cellular resolution of 3μm. Besides the resolution enhancement, multi-view braining imaging can also recover complete signals from deep tissue scattering and attenuation. The identification of long distance neural projections across encephalic regions can be identified and annotated as a result.

  18. PP-SWAT: A phython-based computing software for efficient multiobjective callibration of SWAT

    USDA-ARS?s Scientific Manuscript database

    With enhanced data availability, distributed watershed models for large areas with high spatial and temporal resolution are increasingly used to understand water budgets and examine effects of human activities and climate change/variability on water resources. Developing parallel computing software...

  19. Downscaled soil moisture from SMAP evaluated using high density observations

    USDA-ARS?s Scientific Manuscript database

    Recently, a soil moisture downscaling algorithm based on a regression relationship between daily temperature changes and daily average soil moisture was developed to produce an enhanced spatial resolution on soil moisture product for the Advanced Microwave Scanning Radiometer–EOS (AMSR-E) satellite ...

  20. Downscaling Land Surface Temperature in an Urban Area: A Case Study for Hamburg, Germany

    NASA Astrophysics Data System (ADS)

    Bechtel, Benjamin; Zakšek, Klemen

    2013-04-01

    Land surface temperature (LST) is an important parameter for the urban radiation and heat balance and a boundary condition for the atmospheric urban heat island (UHI). The increase in urban surface temperatures compared to the surrounding area (surface urban heat island, SUHI) has been described and analysed with satellite-based measurements for several decades. Besides continuous progress in the development of new sensors, an operational monitoring is still severely limited by physical constraints regarding the spatial and temporal resolution of the satellite data. Essentially, two measurement concepts must be distinguished: Sensors on geostationary platforms have high temporal (several times per hour) and poor spatial resolution (~ 5 km) while those on low earth orbiters have high spatial (~ 100-1000 m) resolution and a long return period (one day to several weeks). To enable an observation with high temporal and spatial resolution, a downscaling scheme for LST from the Spinning Enhanced Visible Infra-Red Imager (SEVIRI) sensor onboard the geostationary meteorological Meteosat 9 to spatial resolutions between 100 and 1000 m was developed and tested for Hamburg in this case study. Therefore, various predictor sets (including parameters derived from multi-temporal thermal data, NDVI, and morphological parameters) were tested. The relationship between predictors and LST was empirically calibrated in the low resolution domain and then transferred to the high resolution domain. The downscaling was validated with LST data from the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) for the same time. Aggregated parameters from multi-temporal thermal data (in particular annual cycle parameters and principal components) proved particularly suitable. The results for the highest resolution of 100 m showed a high explained variance (R² = 0.71) and relatively low root mean square errors (RMSE = 2.2 K). Larger predictor sets resulted in higher errors, because they tended to overfit. As expected the results were better for coarser spatial resolutions (R² = 0.80, RMSE = 1.8 K for 500 m). These results are similar or slightly better than in previous studies, although we are not aware of any study with a comparably large downscaling factor. A considerable percentage of the error is systematic due to the different viewing geometry of the sensors (the high resolution LST was overestimated about 1.3 K). The study shows that downscaling of SEVIRI LST is possible up to a resolution of 100 m for urban areas and that multi-temporal thermal data are particularly suitable as predictors.

  1. Magnetic field sensing with nitrogen-vacancy color centers in diamond

    NASA Astrophysics Data System (ADS)

    Pham, Linh My

    In recent years, the nitrogen-vacancy (NV) center has emerged as a promising magnetic sensor capable of measuring magnetic fields with high sensitivity and spatial resolution under ambient conditions. This combination of characteristics allows NV magnetometers to probe magnetic structures and systems that were previously inaccessible with alternative magnetic sensing technologies This dissertation presents and discusses a number of the initial efforts to demonstrate and improve NV magnetometry. In particular, a wide-field CCD based NV magnetic field imager capable of micron-scale spatial resolution is demonstrated; and magnetic field alignment, preferential NV orientation, and multipulse dynamical decoupling techniques are explored for enhancing magnetic sensitivity. The further application of dynamical decoupling control sequences as a spectral probe to extract information about the dynamics of the NV spin environment is also discussed; such information may be useful for determining optimal diamond sample parameters for different applications. Finally, several proposed and recently demonstrated applications which take advantage of NV magnetometers' sensitivity and spatial resolution at room temperature are presented, with particular focus on bio-magnetic field imaging.

  2. Intensity-hue-saturation-based image fusion using iterative linear regression

    NASA Astrophysics Data System (ADS)

    Cetin, Mufit; Tepecik, Abdulkadir

    2016-10-01

    The image fusion process basically produces a high-resolution image by combining the superior features of a low-resolution spatial image and a high-resolution panchromatic image. Despite its common usage due to its fast computing capability and high sharpening ability, the intensity-hue-saturation (IHS) fusion method may cause some color distortions, especially when a large number of gray value differences exist among the images to be combined. This paper proposes a spatially adaptive IHS (SA-IHS) technique to avoid these distortions by automatically adjusting the exact spatial information to be injected into the multispectral image during the fusion process. The SA-IHS method essentially suppresses the effects of those pixels that cause the spectral distortions by assigning weaker weights to them and avoiding a large number of redundancies on the fused image. The experimental database consists of IKONOS images, and the experimental results both visually and statistically prove the enhancement of the proposed algorithm when compared with the several other IHS-like methods such as IHS, generalized IHS, fast IHS, and generalized adaptive IHS.

  3. Enhanced ν-optical time domain reflectometry using gigahertz sinusoidally gated InGaAs/InP single-photon avalanche detector

    NASA Astrophysics Data System (ADS)

    Zhang, Xuping; Shi, Yuanlei; Shan, Yuanyuan; Sun, Zhenhong; Qiao, Weiyan; Zhang, Yixin

    2016-09-01

    Optical time domain reflectometry (OTDR) is one of the most successful diagnostic tools for nondestructive attenuation measurement of a fiber link. To achieve better sensitivity, spatial resolution, and avoid dead-zone in conversional OTDR, a single-photon detector has been introduced to form the photon-counting OTDR (ν-OTDR). We have proposed a ν-OTDR system using a gigahertz sinusoidally gated InGaAs/InP single-photon avalanche detector (SPAD). Benefiting from the superior performance of a sinusoidal gated SPAD on dark count probability, gating frequency, and gate duration, our ν-OTDR system has achieved a dynamic range (DR) of 33.4 dB with 1 μs probe pulse width after an equivalent measurement time of 51 s. This obtainable DR corresponds to a sensing length over 150 km. Our system has also obtained a spatial resolution of 5 cm at the end of a 5-km standard single-mode fiber. By employing a sinusoidal gating technique, we have improved the ν-OTDR spatial resolution and significantly reduced the measurement time.

  4. Enhanced spatial resolution on figures versus grounds

    PubMed Central

    Hecht, Lauren N.; Cosman, Joshua D.; Vecera, Shaun P.

    2016-01-01

    Much is known about the cues that determine figure-ground assignment, but less is known about the consequences of figure-ground assignment on later visual processing. Previous work has demonstrated that regions assigned figural status are subjectively more shape-like and salient than background regions. The increase in subjective salience of figural regions could be caused by a number of processes, one of which may be enhanced perceptual processing (e.g., an enhanced neural representation) of figures relative to grounds. We explored this hypothesis by having observers perform a perceptually demanding spatial resolution task in which targets appeared either on figure or ground regions. To rule out a purely attentional account of figural salience, observers discriminated targets on the basis of a region’s color (red or green), which was equally likely to define the figure or the ground. The results of our experiments show that targets appearing on figures were discriminated more accurately than those appearing in ground regions. In addition, targets appearing on figures were discriminated better than those presented in regions considered figurally neutral, but targets appearing within ground regions were discriminated more poorly than those appearing in figurally neutral regions. Taken together, our findings suggest that when two regions share a contour, regions assigned as figure are perceptually enhanced, whereas regions assigned as grounds are perceptually suppressed. PMID:27048441

  5. Enhanced spatial resolution on figures versus grounds.

    PubMed

    Hecht, Lauren N; Cosman, Joshua D; Vecera, Shaun P

    2016-07-01

    Much is known about the cues that determine figure-ground assignment, but less is known about the consequences of figure-ground assignment on later visual processing. Previous work has demonstrated that regions assigned figural status are subjectively more shape-like and salient than background regions. The increase in subjective salience of figural regions could be caused by a number of processes, one of which may be enhanced perceptual processing (e.g., an enhanced neural representation) of figures relative to grounds. We explored this hypothesis by having observers perform a perceptually demanding spatial resolution task in which targets appeared on either figure or ground regions. To rule out a purely attentional account of figural salience, observers discriminated targets on the basis of a region's color (red or green), which was equally likely to define the figure or the ground. The results of our experiments showed that targets appearing on figures were discriminated more accurately than those appearing in ground regions. In addition, targets appearing on figures were discriminated better than those presented in regions considered figurally neutral, but targets appearing within ground regions were discriminated more poorly than those appearing in figurally neutral regions. Taken together, our findings suggest that when two regions share a contour, regions assigned as figure are perceptually enhanced, whereas regions assigned as ground are perceptually suppressed.

  6. High-speed Raman-encoded molecular imaging of freshly excised tissue surfaces with topically applied SERRS nanoparticles

    NASA Astrophysics Data System (ADS)

    Wang, Yu "Winston"; Yang, Qian; Kang, Soyoung; Wall, Matthew A.; Liu, Jonathan T. C.

    2018-04-01

    Surface-enhanced Raman scattering (SERS) nanoparticles (NPs) are increasingly being engineered for a variety of disease-detection and treatment applications. For example, we have previously developed a fiber-optic Raman-encoded molecular imaging (REMI) system for spectral imaging of biomarker-targeted SERS NPs topically applied on tissue surfaces to identify residual tumors at surgical margins. Although accurate tumor detection was achieved, the commercial SERS NPs used in our previous studies lacked the signal strength to enable high-speed imaging with high pixel counts (large fields of view and/or high spatial resolution), which limits their use for certain time-constrained clinical applications. As a solution, we explored the use of surface-enhanced resonant Raman scattering (SERRS) NPs to enhance imaging speeds. The SERRS NPs were synthesized de novo, and then conjugated to HER2 antibodies to achieve high binding affinity, as validated by flow cytometry. Under identical tissue-staining and imaging conditions, the targeted SERRS NPs enabled reliable identification of HER2-overexpressed tumor xenografts with 50-fold-enhanced imaging speed compared with our standard targeted SERS NPs. This enables our REMI system to image tissue surfaces at a rate of 150 cm2 per minute at a spatial resolution of 0.5 mm.

  7. Combined Dynamic Contrast Enhanced Liver MRI and MRA Using Interleaved Variable Density Sampling

    PubMed Central

    Rahimi, Mahdi Salmani; Korosec, Frank R.; Wang, Kang; Holmes, James H.; Motosugi, Utaroh; Bannas, Peter; Reeder, Scott B.

    2014-01-01

    Purpose To develop and evaluate a method for volumetric contrast-enhanced MR imaging of the liver, with high spatial and temporal resolutions, for combined dynamic imaging and MR angiography using a single injection of contrast. Methods An interleaved variable density (IVD) undersampling pattern was implemented in combination with a real-time-triggered, time-resolved, dual-echo 3D spoiled gradient echo sequence. Parallel imaging autocalibration lines were acquired only once during the first time-frame. Imaging was performed in ten subjects with focal nodular hyperplasia (FNH) and compared with their clinical MRI. The angiographic phase of the proposed method was compared to a dedicated MR angiogram acquired during a second injection of contrast. Results A total of 21 FNH, 3 cavernous hemangiomas, and 109 arterial segments were visualized in 10 subjects. The temporally-resolved images depicted the characteristic arterial enhancement pattern of the lesions with a 4 s update rate. Images were graded as having significantly higher quality compared to the clinical MRI. Angiograms produced from the IVD method provided non-inferior diagnostic assessment compared to the dedicated MRA. Conclusion Using an undersampled IVD imaging method, we have demonstrated the feasibility of obtaining high spatial and temporal resolution dynamic contrast-enhanced imaging and simultaneous MRA of the liver. PMID:24639130

  8. Velocity distributions in a micromixer measured by NMR imaging.

    PubMed

    Ahola, Susanna; Telkki, Ville-Veikko; Stapf, Siegfried

    2012-04-24

    Velocity distributions (so-called propagators) with two-dimensional spatial resolution inside a chemical micromixer were measured by pulsed-field-gradient spin-echo (PGSE) nuclear magnetic resonance (NMR). A surface coil matching the volume of interest was built to enhance the signal-to-noise ratio. This enabled the acquisition of velocity maps with a very high spatial resolution of 29 μm × 39 μm. The measured propagators are compared with theoretical distributions and a good agreement is found. The results show that the propagator data provide much richer information about flow behaviour than conventional NMR velocity imaging and the information is essential for understanding the performance of a micromixer. It reveals, for example, deviations in the shape and size of the channel structures and multicomponent flow velocity distribution of overlapping channels. Propagator data efficiently compensate lost information caused by insufficient 3D resolution in conventional velocity imaging.

  9. Exogenous attention enhances 2nd-order contrast sensitivity

    PubMed Central

    Barbot, Antoine; Landy, Michael S.; Carrasco, Marisa

    2011-01-01

    Natural scenes contain a rich variety of contours that the visual system extracts to segregrate the retinal image into perceptually coherent regions. Covert spatial attention helps extract contours by enhancing contrast sensitivity for 1st-order, luminance-defined patterns at attended locations, while reducing sensitivity at unattended locations, relative to neutral attention allocation. However, humans are also sensitive to 2nd-order patterns such as spatial variations of texture, which are predominant in natural scenes and cannot be detected by linear mechanisms. We assess whether and how exogenous attention—the involuntary and transient capture of spatial attention—affects the contrast sensitivity of channels sensitive to 2nd-order, texture-defined patterns. Using 2nd-order, texture-defined stimuli, we demonstrate that exogenous attention increases 2nd-order contrast sensitivity at the attended location, while decreasing it at unattended locations, relative to a neutral condition. By manipulating both 1st- and 2nd-order spatial frequency, we find that the effects of attention depend both on 2nd-order spatial frequency of the stimulus and the observer’s 2nd-order spatial resolution at the target location. At parafoveal locations, attention enhances 2nd-order contrast sensitivity to high, but not to low 2nd-order spatial frequencies; at peripheral locations attention also enhances sensitivity to low 2nd-order spatial frequencies. Control experiments rule out the possibility that these effects might be due to an increase in contrast sensitivity at the 1st-order stage of visual processing. Thus, exogenous attention affects 2nd-order contrast sensitivity at both attended and unattended locations. PMID:21356228

  10. Enhancing image contrast of carbon nanotubes on cellular background using helium ion microscope by varying helium ion fluence.

    PubMed

    Dykas, M M; Poddar, K; Yoong, S L; Viswanathan, V; Mathew, S; Patra, A; Saha, S; Pastorin, G; Venkatesan, T

    2018-01-01

    Carbon nanotubes (CNTs) have become an important nano entity for biomedical applications. Conventional methods of their imaging, often cannot be applied in biological samples due to an inadequate spatial resolution or poor contrast between the CNTs and the biological sample. Here we report a unique and effective detection method, which uses differences in conductivities of carbon nanotubes and HeLa cells. The technique involves the use of a helium ion microscope to image the sample with the surface charging artefacts created by the He + and neutralised by electron flood gun. This enables us to obtain a few nanometre resolution images of CNTs in HeLa Cells with high contrast, which was achieved by tailoring the He + fluence. Charging artefacts can be efficiently removed for conductive CNTs by a low amount of electrons, the fluence of which is not adequate to discharge the cell surface, resulting in high image contrast. Thus, this technique enables rapid detection of any conducting nano structures on insulating cellular background even in large fields of view and fine spatial resolution. The technique demonstrated has wider applications for researchers seeking enhanced contrast and high-resolution imaging of any conducting entity in a biological matrix - a commonly encountered issue of importance in drug delivery, tissue engineering and toxicological studies. © 2017 The Authors Journal of Microscopy © 2017 Royal Microscopical Society.

  11. LOR-interleaving image reconstruction for PET imaging with fractional-crystal collimation

    NASA Astrophysics Data System (ADS)

    Li, Yusheng; Matej, Samuel; Karp, Joel S.; Metzler, Scott D.

    2015-01-01

    Positron emission tomography (PET) has become an important modality in medical and molecular imaging. However, in most PET applications, the resolution is still mainly limited by the physical crystal sizes or the detector’s intrinsic spatial resolution. To achieve images with better spatial resolution in a central region of interest (ROI), we have previously proposed using collimation in PET scanners. The collimator is designed to partially mask detector crystals to detect lines of response (LORs) within fractional crystals. A sequence of collimator-encoded LORs is measured with different collimation configurations. This novel collimated scanner geometry makes the reconstruction problem challenging, as both detector and collimator effects need to be modeled to reconstruct high-resolution images from collimated LORs. In this paper, we present a LOR-interleaving (LORI) algorithm, which incorporates these effects and has the advantage of reusing existing reconstruction software, to reconstruct high-resolution images for PET with fractional-crystal collimation. We also develop a 3D ray-tracing model incorporating both the collimator and crystal penetration for simulations and reconstructions of the collimated PET. By registering the collimator-encoded LORs with the collimator configurations, high-resolution LORs are restored based on the modeled transfer matrices using the non-negative least-squares method and EM algorithm. The resolution-enhanced images are then reconstructed from the high-resolution LORs using the MLEM or OSEM algorithm. For validation, we applied the LORI method to a small-animal PET scanner, A-PET, with a specially designed collimator. We demonstrate through simulated reconstructions with a hot-rod phantom and MOBY phantom that the LORI reconstructions can substantially improve spatial resolution and quantification compared to the uncollimated reconstructions. The LORI algorithm is crucial to improve overall image quality of collimated PET, which can have significant implications in preclinical and clinical ROI imaging applications.

  12. Performance of Orbital Neutron Instruments for Spatially Resolved Hydrogen Measurements of Airless Planetary Bodies

    PubMed Central

    Elphic, Richard C.; Feldman, William C.; Funsten, Herbert O.; Prettyman, Thomas H.

    2010-01-01

    Abstract Orbital neutron spectroscopy has become a standard technique for measuring planetary surface compositions from orbit. While this technique has led to important discoveries, such as the deposits of hydrogen at the Moon and Mars, a limitation is its poor spatial resolution. For omni-directional neutron sensors, spatial resolutions are 1–1.5 times the spacecraft's altitude above the planetary surface (or 40–600 km for typical orbital altitudes). Neutron sensors with enhanced spatial resolution have been proposed, and one with a collimated field of view is scheduled to fly on a mission to measure lunar polar hydrogen. No quantitative studies or analyses have been published that evaluate in detail the detection and sensitivity limits of spatially resolved neutron measurements. Here, we describe two complementary techniques for evaluating the hydrogen sensitivity of spatially resolved neutron sensors: an analytic, closed-form expression that has been validated with Lunar Prospector neutron data, and a three-dimensional modeling technique. The analytic technique, called the Spatially resolved Neutron Analytic Sensitivity Approximation (SNASA), provides a straightforward method to evaluate spatially resolved neutron data from existing instruments as well as to plan for future mission scenarios. We conclude that the existing detector—the Lunar Exploration Neutron Detector (LEND)—scheduled to launch on the Lunar Reconnaissance Orbiter will have hydrogen sensitivities that are over an order of magnitude poorer than previously estimated. We further conclude that a sensor with a geometric factor of ∼ 100 cm2 Sr (compared to the LEND geometric factor of ∼ 10.9 cm2 Sr) could make substantially improved measurements of the lunar polar hydrogen spatial distribution. Key Words: Planetary instrumentation—Planetary science—Moon—Spacecraft experiments—Hydrogen. Astrobiology 10, 183–200. PMID:20298147

  13. Vibrational spectroscopy in the electron microscope.

    PubMed

    Krivanek, Ondrej L; Lovejoy, Tracy C; Dellby, Niklas; Aoki, Toshihiro; Carpenter, R W; Rez, Peter; Soignard, Emmanuel; Zhu, Jiangtao; Batson, Philip E; Lagos, Maureen J; Egerton, Ray F; Crozier, Peter A

    2014-10-09

    Vibrational spectroscopies using infrared radiation, Raman scattering, neutrons, low-energy electrons and inelastic electron tunnelling are powerful techniques that can analyse bonding arrangements, identify chemical compounds and probe many other important properties of materials. The spatial resolution of these spectroscopies is typically one micrometre or more, although it can reach a few tens of nanometres or even a few ångströms when enhanced by the presence of a sharp metallic tip. If vibrational spectroscopy could be combined with the spatial resolution and flexibility of the transmission electron microscope, it would open up the study of vibrational modes in many different types of nanostructures. Unfortunately, the energy resolution of electron energy loss spectroscopy performed in the electron microscope has until now been too poor to allow such a combination. Recent developments that have improved the attainable energy resolution of electron energy loss spectroscopy in a scanning transmission electron microscope to around ten millielectronvolts now allow vibrational spectroscopy to be carried out in the electron microscope. Here we describe the innovations responsible for the progress, and present examples of applications in inorganic and organic materials, including the detection of hydrogen. We also demonstrate that the vibrational signal has both high- and low-spatial-resolution components, that the first component can be used to map vibrational features at nanometre-level resolution, and that the second component can be used for analysis carried out with the beam positioned just outside the sample--that is, for 'aloof' spectroscopy that largely avoids radiation damage.

  14. [Basic examination of an imagecharacteristic in Multivane].

    PubMed

    Ohshita, Tsuyoshi

    2011-01-01

    Deterioration in the image because of a patient's movement always becomes a problem in the MRI inspection. To solve this problem, the imaging procedure named Multivane was developed. The principle is similar to the periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) method. As for Multivane, the effect of the body motion correction is high. However, the filling method of k space is different than a past Cartesian method. A basic examination of the image characteristic of Multivane and Cartesian was utilized along with geostationary phantom. The examination items are SNR, CNR, and a spatial resolution. As a result, Multivane of SNR was high. Cartesian of the contrast and the spatial resolution was also high. It is important to recognize these features and to use Multivane.

  15. Micro-CT at the imaging beamline P05 at PETRA III

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wilde, Fabian, E-mail: fabian.wilde@hzg.de; Ogurreck, Malte; Greving, Imke

    2016-07-27

    The Imaging Beamline (IBL) P05 is operated by the Helmholtz-Zentrum Geesthacht and located at the DESY storage ring PETRA III. IBL is dedicated to X-ray full field imaging and consists of two experimental end stations. A micro tomography end station equipped for spatial resolutions down to 1 µm and a nano tomography end station for spatial resolutions down to 100 nm. The micro tomography end station is in user operation since 2013 and offers imaging with absorption contrast, phase enhanced absorption contrast and phase contrast methods. We report here on the current status and developments of the micro tomography endmore » station including technical descriptions and show examples of research performed at P05.« less

  16. Apertureless near-field vibrational imaging of block-copolymer nanostructures with ultrahigh spatial resolution.

    PubMed

    Raschke, Markus B; Molina, Leopoldo; Elsaesser, Thomas; Kim, Dong Ha; Knoll, Wolfgang; Hinrichs, Karsten

    2005-10-14

    Nanodomains formed by microphase separation in thin films of the diblock copolymers poly(styrene-b-2-vinylpyridine) (PS-b-P2VP) and poly(styrene-b-ethyleneoxide) (PS-b-PEO) were imaged by means of infrared scattering-type near-field microscopy. When probing at 3.39 mum (2950 cm(-1)), contrast is obtained due to spectral differences between the C--H stretching vibrational resonances of the respective polymer constituents. An all-optical spatial resolution better than 10 nm was achieved, which corresponds to a sensitivity of just several thousand C--H groups facilitated by the local-field enhancement at the sharp metallic probe tips. The results demonstrate that infrared spectroscopy with access to intramolecular dimensions is within reach.

  17. Ultrafast time-resolved photoemission of a metallic tip/substrate junction

    NASA Astrophysics Data System (ADS)

    Meng, Xiang; Jin, Wencan; Yang, Hao; Dadap, Jerry; Osgood, Richard; Camillone, Nicholas, III

    The strong near-field enhancement of metallic-tip nanostructures has attracted great interest in scanning microscopy techniques, such as surface-enhanced Raman scattering, near-field scanning optical microscopy and tip-enhanced nonlinear imaging. In this talk, we use a full vectorial 3D-FDTD method to investigate the spatial characteristics of the optical field confinement and localization between a tungsten nanoprobe and an infinite planar silver substrate, with two-color ultrafast laser excitation scheme. The degree of two-color excited field enhancement, geometry dependence, the exact mechanism of optical tip-substrate coupling and tip-substrate plasmon resonances are significant in understanding the electrodynamical responses at tip-substrate junction. The demonstrated measurements with subpicosecond time and subnanometer spatial resolution suggest a new approach to ultrafast time-resolved measurements of surface electron dynamics. DE-FG 02-90-ER-14104; DE-FG 02-04-ER-46157.

  18. Resolution Enhancement in PET Reconstruction Using Collimation

    NASA Astrophysics Data System (ADS)

    Metzler, Scott D.; Matej, Samuel; Karp, Joel S.

    2013-02-01

    Collimation can improve both the spatial resolution and sampling properties compared to the same scanner without collimation. Spatial resolution improves because each original crystal can be conceptually split into two (i.e., doubling the number of in-plane crystals) by masking half the crystal with a high-density attenuator (e.g., tungsten); this reduces coincidence efficiency by 4× since both crystals comprising the line of response (LOR) are masked, but yields 4× as many resolution-enhanced (RE) LORs. All the new RE LORs can be measured by scanning with the collimator in different configurations.In this simulation study, the collimator was assumed to be ideal, neither allowing gamma penetration nor truncating the field of view. Comparisons were made in 2D between an uncollimated small-animal system with 2-mm crystals that were assumed to be perfectly absorbing and the same system with collimation that narrowed the effective crystal size to 1 mm. Digital phantoms included a hot-rod and a single-hot-spot, both in a uniform background with activity ratio of 4:1. In addition to the collimated and uncollimated configurations, angular and spatial wobbling acquisitions of the 2-mm case were also simulated. Similarly, configurations with different combinations of the RE LORs were considered including (i) all LORs, (ii) only those parallel to the 2-mm LORs; and (iii) only cross pairs that are not parallel to the 2-mm LORs. Lastly, quantitative studies were conducted for collimated and uncollimated data using contrast recovery coefficient and mean-squared error (MSE) as metrics. The reconstructions show that for most noise levels there is a substantial improvement in image quality (i.e., visual quality, resolution, and a reduction in artifacts) by using collimation even when there are 4 fewer counts or-in some cases-comparing with the noiseless uncollimated reconstruction. By comparing various configurations of sampling, the results show that it is the matched combination of both improved spatial resolution of each LOR and the increase in the number of LORs that yields improved reconstructions. Further, the quantitative studies show that for low-count scans, the collimated data give better MSE for small lesions and the uncollimated data give better MSE for larger lesions; for highcount studies, the collimated data yield better quantitative values for the entire range of lesion sizes that were evaluated.

  19. Spatial entanglement patterns and Einstein-Podolsky-Rosen steering in Bose-Einstein condensates

    NASA Astrophysics Data System (ADS)

    Fadel, Matteo; Zibold, Tilman; Décamps, Boris; Treutlein, Philipp

    2018-04-01

    Many-particle entanglement is a fundamental concept of quantum physics that still presents conceptual challenges. Although nonclassical states of atomic ensembles were used to enhance measurement precision in quantum metrology, the notion of entanglement in these systems was debated because the correlations among the indistinguishable atoms were witnessed by collective measurements only. Here, we use high-resolution imaging to directly measure the spin correlations between spatially separated parts of a spin-squeezed Bose-Einstein condensate. We observe entanglement that is strong enough for Einstein-Podolsky-Rosen steering: We can predict measurement outcomes for noncommuting observables in one spatial region on the basis of corresponding measurements in another region with an inferred uncertainty product below the Heisenberg uncertainty bound. This method could be exploited for entanglement-enhanced imaging of electromagnetic field distributions and quantum information tasks.

  20. An Attention-Information-Based Spatial Adaptation Framework for Browsing Videos via Mobile Devices

    NASA Astrophysics Data System (ADS)

    Li, Houqiang; Wang, Yi; Chen, Chang Wen

    2007-12-01

    With the growing popularity of personal digital assistant devices and smart phones, more and more consumers are becoming quite enthusiastic to appreciate videos via mobile devices. However, limited display size of the mobile devices has been imposing significant barriers for users to enjoy browsing high-resolution videos. In this paper, we present an attention-information-based spatial adaptation framework to address this problem. The whole framework includes two major parts: video content generation and video adaptation system. During video compression, the attention information in video sequences will be detected using an attention model and embedded into bitstreams with proposed supplement-enhanced information (SEI) structure. Furthermore, we also develop an innovative scheme to adaptively adjust quantization parameters in order to simultaneously improve the quality of overall encoding and the quality of transcoding the attention areas. When the high-resolution bitstream is transmitted to mobile users, a fast transcoding algorithm we developed earlier will be applied to generate a new bitstream for attention areas in frames. The new low-resolution bitstream containing mostly attention information, instead of the high-resolution one, will be sent to users for display on the mobile devices. Experimental results show that the proposed spatial adaptation scheme is able to improve both subjective and objective video qualities.

  1. Tip-enhanced Raman scattering of DNA aptamers for Listeria monocytogenes.

    PubMed

    He, Siyu; Li, Hongyuan; Gomes, Carmen L; Voronine, Dmitri V

    2018-05-03

    Optical detection and conformational mapping of aptamers are important for improving medical and biosensing technologies and for better understanding of biological processes at the molecular level. The authors investigate the vibrational signals of deoxyribonucleic acid aptamers specific to Listeria monocytogenes immobilized on gold substrates using tip-enhanced Raman scattering (TERS) spectroscopy and nanoscale imaging. The authors compare topographic and nano-optical signals and investigate the fluctuations of the position-dependent TERS spectra. They perform spatial TERS mapping with 3 nm step size and discuss the limitation of the resulting spatial resolution under the ambient conditions. TERS mapping provides information about the chemical composition and conformation of aptamers and paves the way to future label-free biosensing.

  2. Estimation of net ecosystem production in Asia using the diagnostic-type ecosystem model with a 10 km grid-scale resolution

    NASA Astrophysics Data System (ADS)

    Sasai, Takahiro; Obikawa, Hiroki; Murakami, Kazutaka; Kato, Soushi; Matsunaga, Tsuneo; Nemani, Ramakrishna R.

    2016-06-01

    The terrestrial carbon cycle in Asia is highly uncertain, and it affects our understanding of global warming. One of the important issues is the need for an enhancement of spatial resolution, since local regions in Asia are heterogeneous with regard to meteorology, land form, and land cover type, which greatly impacts the detailed spatial patterns in its ecosystem. Thus, an important goal of this study is to reasonably reproduce the heterogeneous biogeochemical patterns in Asia by enhancing the spatial resolution of the ecosystem model biosphere model integrating eco-physiological and mechanistic approaches using satellite data (BEAMS). We estimated net ecosystem production (NEP) over eastern Asia and examined the spatial differences in the factors controlling NEP by using a 10 km grid-scale approach over two different decades (2001-2010 and 2091-2100). The present and future meteorological inputs were derived from satellite observations and the downscaled Coupled Model Intercomparison Project Phase 5 (CMIP5) data set, respectively. The results showed that the present NEP in whole eastern Asia was carbon source (-214.9 TgC yr-1) and in future scenarios, the greatest positive (76.4 TgC yr-1) and least negative (-95.9 TgC yr-1) NEPs were estimated from the Representative Concentration Pathways (RCP) 6.0 and RCP8.5 scenarios, respectively. Calculated annual NEP in RCP8.5 was mostly positive in the southern part of East Asia and Southeast Asia and negative in northern and central parts of East Asia. Under the RCP scenario with higher greenhouse gases emission (RCP8.5), deciduous needleleaf and mixed forests distributed in the middle and high latitudes served as carbon source. In contrast, evergreen broadleaf forests distributed in low latitudes served as carbon sink. The sensitivity study demonstrated that the spatial tendency of NEP was largely influenced by atmospheric CO2 and temperature.

  3. Local signaling from a retinal prosthetic in a rodent retinitis pigmentosa model in vivo

    NASA Astrophysics Data System (ADS)

    Fransen, James W.; Pangeni, Gobinda; Pardue, Machelle T.; McCall, Maureen A.

    2014-08-01

    Objective. In clinical trials, retinitis pigmentosa patients implanted with a retinal prosthetic device show enhanced spatial vision, including the ability to read large text and navigate. New prosthetics aim to increase spatial resolution by decreasing pixel/electrode size and limiting current spread. To examine spatial resolution of a new prosthetic design, we characterized and compared two photovoltaic array (PVA) designs and their interaction with the retina after subretinal implantation in transgenic S334ter line 3 rats (Tg S334ter-3). Approach. PVAs were implanted subretinally at two stages of degeneration and assessed in vivo using extracellular recordings in the superior colliculus (SC). Several aspects of this interaction were evaluated by varying duration, irradiance and position of a near infrared laser focused on the PVA. These characteristics included: activation threshold, response linearity, SC signal topography and spatial localization. The major design difference between the two PVA designs is the inclusion of local current returns in the newer design. Main results. When tested in vivo, PVA-evoked response thresholds were independent of pixel/electrode size, but differ between the new and old PVA designs. Response thresholds were independent of implantation age and duration (⩽7.5 months). For both prosthesis designs, threshold intensities were within established safety limits. PVA-evoked responses require inner retina synaptic transmission and do not directly activate retinal ganglion cells. The new PVA design evokes local retinal activation, which is not found with the older PVA design that lacks local current returns. Significance. Our study provides in vivo evidence that prosthetics make functional contacts with the inner nuclear layer at several stages of degeneration. The new PVA design enhances local activation within the retina and SC. Together these results predict that the new design can potentially harness the inherent processing within the retina and is likely to produce higher spatial resolution in patients.

  4. Efficient multi-objective calibration of a computationally intensive hydrologic model with parallel computing software in Python

    USDA-ARS?s Scientific Manuscript database

    With enhanced data availability, distributed watershed models for large areas with high spatial and temporal resolution are increasingly used to understand water budgets and examine effects of human activities and climate change/variability on water resources. Developing parallel computing software...

  5. Effects of spatial resolution ratio in image fusion

    USGS Publications Warehouse

    Ling, Y.; Ehlers, M.; Usery, E.L.; Madden, M.

    2008-01-01

    In image fusion, the spatial resolution ratio can be defined as the ratio between the spatial resolution of the high-resolution panchromatic image and that of the low-resolution multispectral image. This paper attempts to assess the effects of the spatial resolution ratio of the input images on the quality of the fused image. Experimental results indicate that a spatial resolution ratio of 1:10 or higher is desired for optimal multisensor image fusion provided the input panchromatic image is not downsampled to a coarser resolution. Due to the synthetic pixels generated from resampling, the quality of the fused image decreases as the spatial resolution ratio decreases (e.g. from 1:10 to 1:30). However, even with a spatial resolution ratio as small as 1:30, the quality of the fused image is still better than the original multispectral image alone for feature interpretation. In cases where the spatial resolution ratio is too small (e.g. 1:30), to obtain better spectral integrity of the fused image, one may downsample the input high-resolution panchromatic image to a slightly lower resolution before fusing it with the multispectral image.

  6. New features in Saturn's atmosphere revealed by high-resolution thermal infrared images

    NASA Technical Reports Server (NTRS)

    Gezari, D. Y.; Mumma, M. J.; Espenak, F.; Deming, D.; Bjoraker, G.; Woods, L.; Folz, W.

    1989-01-01

    Observations of the stratospheric IR emission structure on Saturn are presented. The high-spatial-resolution global images show a variety of new features, including a narrow equatorial belt of enhanced emission at 7.8 micron, a prominent symmetrical north polar hotspot at all three wavelengths, and a midlatitude structure which is asymmetrically brightened at the east limb. The results confirm the polar brightening and reversal in position predicted by recent models for seasonal thermal variations of Saturn's stratosphere.

  7. A resolution expressing support for the designation of Saint Louis, Missouri, as the "National Chess Capital" of the United States to enhance awareness of the educational benefits of chess and to encourage schools and community centers to engage in chess programs to promote problem-solving, critical thinking, spatial awareness, and goal setting.

    THOMAS, 113th Congress

    Sen. McCaskill, Claire [D-MO

    2013-04-18

    Senate - 05/05/2014 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

  8. High spatial resolution shortwave infrared imaging technology based on time delay and digital accumulation method

    NASA Astrophysics Data System (ADS)

    Jia, Jianxin; Wang, Yueming; Zhuang, Xiaoqiong; Yao, Yi; Wang, Shengwei; Zhao, Ding; Shu, Rong; Wang, Jianyu

    2017-03-01

    Shortwave infrared (SWIR) imaging technology attracts more and more attention by its fascinating ability of penetrating haze and smoke. For application of spaceborne remote sensing, spatial resolution of SWIR is lower compared with that of visible light (VIS) wavelength. It is difficult to balance between the spatial resolution and signal to noise ratio (SNR). Some conventional methods, such as enlarging aperture of telescope, image motion compensation, and analog time delay and integration (TDI) technology are used to gain SNR. These techniques bring in higher cost of satellite, complexity of system or other negative factors. In this paper, time delay and digital accumulation (TDDA) method is proposed to achieve higher spatial resolution. The method can enhance the SNR and non-uniformity of system theoretically. A prototype of SWIR imager consists of opto-mechanical, 1024 × 128 InGaAs detector, and electronics is designed and integrated to prove TDDA method. Both of measurements and experimental results indicate TDDA method can promote SNR of system approximated of the square root of accumulative stage. The results exhibit that non-uniformity of system is also improved by this approach to some extent. The experiment results are corresponded with the theoretical analysis. Based on the experiments results, it is proved firstly that the goal of 1 m ground sample distance (GSD) in orbit of 500 km is feasible with the TDDA stage of 30 for SWIR waveband (0.9-1.7 μm).

  9. Optimal arrangements of fiber optic probes to enhance the spatial resolution in depth for 3D reflectance diffuse optical tomography with time-resolved measurements performed with fast-gated single-photon avalanche diodes

    NASA Astrophysics Data System (ADS)

    Puszka, Agathe; Di Sieno, Laura; Dalla Mora, Alberto; Pifferi, Antonio; Contini, Davide; Boso, Gianluca; Tosi, Alberto; Hervé, Lionel; Planat-Chrétien, Anne; Koenig, Anne; Dinten, Jean-Marc

    2014-02-01

    Fiber optic probes with a width limited to a few centimeters can enable diffuse optical tomography (DOT) in intern organs like the prostate or facilitate the measurements on extern organs like the breast or the brain. We have recently shown on 2D tomographic images that time-resolved measurements with a large dynamic range obtained with fast-gated single-photon avalanche diodes (SPADs) could push forward the imaged depth range in a diffusive medium at short source-detector separation compared with conventional non-gated approaches. In this work, we confirm these performances with the first 3D tomographic images reconstructed with such a setup and processed with the Mellin- Laplace transform. More precisely, we investigate the performance of hand-held probes with short interfiber distances in terms of spatial resolution and specifically demonstrate the interest of having a compact probe design featuring small source-detector separations. We compare the spatial resolution obtained with two probes having the same design but different scale factors, the first one featuring only interfiber distances of 15 mm and the second one, 10 mm. We evaluate experimentally the spatial resolution obtained with each probe on the setup with fast-gated SPADs for optical phantoms featuring two absorbing inclusions positioned at different depths and conclude on the potential of short source-detector separations for DOT.

  10. Design and characterization of a dead-time regime enhanced early photon projection imaging system

    NASA Astrophysics Data System (ADS)

    Sinha, L.; Fogarty, M.; Zhou, W.; Giudice, A.; Brankov, J. G.; Tichauer, K. M.

    2018-04-01

    Scattering of visible and near-infrared light in biological tissue reduces spatial resolution for imaging of tissues thicker than 100 μm. In this study, an optical projection imaging system is presented and characterized that exploits the dead-time characteristics typical of photon counting modules based on single photon avalanche diodes (SPADs). With this system, it is possible to attenuate the detection of more scattered late-arriving photons, such that detection of less scattered early-arriving photons can be enhanced with increased light intensity, without being impeded by the maximum count rate of the SPADs. The system has the potential to provide transmittance-based anatomical information or fluorescence-based functional information (with slight modification in the instrumentation) of biological samples with improved resolution in the mesoscopic domain (0.1-2 cm). The system design, calibration, stability, and performance were evaluated using simulation and experimental phantom studies. The proposed system allows for the detection of very-rare early-photons at a higher frequency and with a better signal-to-noise ratio. The experimental results demonstrated over a 3.4-fold improvement in the spatial resolution using early photon detection vs. conventional detection, and a 1000-fold improvement in imaging time using enhanced early detection vs. conventional early photon detection in a 4-mm thick phantom with a tissue-equivalent absorption coefficient of μa = 0.05 mm-1 and a reduced scattering coefficient of μs' = 5 mm-1.

  11. Optical vs. electronic enhancement of remote sensing imagery

    NASA Technical Reports Server (NTRS)

    Colwell, R. N.; Katibah, E. F.

    1976-01-01

    Basic aspects of remote sensing are considered and a description is provided of the methods which are employed in connection with the optical or electronic enhancement of remote sensing imagery. The advantages and limitations of various image enhancement methods and techniques are evaluated. It is pointed out that optical enhancement methods and techniques are currently superior to electronic ones with respect to spatial resolution and equipment cost considerations. Advantages of electronic procedures, on the other hand, are related to a greater flexibility regarding the presentation of the information as an aid for the interpretation by the image analyst.

  12. An enhanced TIMESAT algorithm for estimating vegetation phenology metrics from MODIS data

    USGS Publications Warehouse

    Tan, B.; Morisette, J.T.; Wolfe, R.E.; Gao, F.; Ederer, G.A.; Nightingale, J.; Pedelty, J.A.

    2011-01-01

    An enhanced TIMESAT algorithm was developed for retrieving vegetation phenology metrics from 250 m and 500 m spatial resolution Moderate Resolution Imaging Spectroradiometer (MODIS) vegetation indexes (VI) over North America. MODIS VI data were pre-processed using snow-cover and land surface temperature data, and temporally smoothed with the enhanced TIMESAT algorithm. An objective third derivative test was applied to define key phenology dates and retrieve a set of phenology metrics. This algorithm has been applied to two MODIS VIs: Normalized Difference Vegetation Index (NDVI) and Enhanced Vegetation Index (EVI). In this paper, we describe the algorithm and use EVI as an example to compare three sets of TIMESAT algorithm/MODIS VI combinations: a) original TIMESAT algorithm with original MODIS VI, b) original TIMESAT algorithm with pre-processed MODIS VI, and c) enhanced TIMESAT and pre-processed MODIS VI. All retrievals were compared with ground phenology observations, some made available through the National Phenology Network. Our results show that for MODIS data in middle to high latitude regions, snow and land surface temperature information is critical in retrieving phenology metrics from satellite observations. The results also show that the enhanced TIMESAT algorithm can better accommodate growing season start and end dates that vary significantly from year to year. The TIMESAT algorithm improvements contribute to more spatial coverage and more accurate retrievals of the phenology metrics. Among three sets of TIMESAT/MODIS VI combinations, the start of the growing season metric predicted by the enhanced TIMESAT algorithm using pre-processed MODIS VIs has the best associations with ground observed vegetation greenup dates. ?? 2010 IEEE.

  13. An Enhanced TIMESAT Algorithm for Estimating Vegetation Phenology Metrics from MODIS Data

    NASA Technical Reports Server (NTRS)

    Tan, Bin; Morisette, Jeffrey T.; Wolfe, Robert E.; Gao, Feng; Ederer, Gregory A.; Nightingale, Joanne; Pedelty, Jeffrey A.

    2012-01-01

    An enhanced TIMESAT algorithm was developed for retrieving vegetation phenology metrics from 250 m and 500 m spatial resolution Moderate Resolution Imaging Spectroradiometer (MODIS) vegetation indexes (VI) over North America. MODIS VI data were pre-processed using snow-cover and land surface temperature data, and temporally smoothed with the enhanced TIMESAT algorithm. An objective third derivative test was applied to define key phenology dates and retrieve a set of phenology metrics. This algorithm has been applied to two MODIS VIs: Normalized Difference Vegetation Index (NDVI) and Enhanced Vegetation Index (EVI). In this paper, we describe the algorithm and use EVI as an example to compare three sets of TIMESAT algorithm/MODIS VI combinations: a) original TIMESAT algorithm with original MODIS VI, b) original TIMESAT algorithm with pre-processed MODIS VI, and c) enhanced TIMESAT and pre-processed MODIS VI. All retrievals were compared with ground phenology observations, some made available through the National Phenology Network. Our results show that for MODIS data in middle to high latitude regions, snow and land surface temperature information is critical in retrieving phenology metrics from satellite observations. The results also show that the enhanced TIMESAT algorithm can better accommodate growing season start and end dates that vary significantly from year to year. The TIMESAT algorithm improvements contribute to more spatial coverage and more accurate retrievals of the phenology metrics. Among three sets of TIMESAT/MODIS VI combinations, the start of the growing season metric predicted by the enhanced TIMESAT algorithm using pre-processed MODIS VIs has the best associations with ground observed vegetation greenup dates.

  14. Enhanced Seismic Imaging of Turbidite Deposits in Chicontepec Basin, Mexico

    NASA Astrophysics Data System (ADS)

    Chavez-Perez, S.; Vargas-Meleza, L.

    2007-05-01

    We test, as postprocessing tools, a combination of migration deconvolution and geometric attributes to attack the complex problems of reflector resolution and detection in migrated seismic volumes. Migration deconvolution has been empirically shown to be an effective approach for enhancing the illumination of migrated images, which are blurred versions of the subsurface reflectivity distribution, by decreasing imaging artifacts, improving spatial resolution, and alleviating acquisition footprint problems. We utilize migration deconvolution as a means to improve the quality and resolution of 3D prestack time migrated results from Chicontepec basin, Mexico, a very relevant portion of the producing onshore sector of Pemex, the Mexican petroleum company. Seismic data covers the Agua Fria, Coapechaca, and Tajin fields. It exhibits acquisition footprint problems, migration artifacts and a severe lack of resolution in the target area, where turbidite deposits need to be characterized between major erosional surfaces. Vertical resolution is about 35 m and the main hydrocarbon plays are turbidite beds no more than 60 m thick. We also employ geometric attributes (e.g., coherent energy and curvature), computed after migration deconvolution, to detect and map out depositional features, and help design development wells in the area. Results of this workflow show imaging enhancement and allow us to identify meandering channels and individual sand bodies, previously undistinguishable in the original seismic migrated images.

  15. High Resolution Insights into Snow Distribution Provided by Drone Photogrammetry

    NASA Astrophysics Data System (ADS)

    Redpath, T.; Sirguey, P. J.; Cullen, N. J.; Fitzsimons, S.

    2017-12-01

    Dynamic in time and space, New Zealand's seasonal snow is largely confined to remote alpine areas, complicating ongoing in situ measurement and characterisation. Improved understanding and modeling of the seasonal snowpack requires fine scale resolution of snow distribution and spatial variability. The potential of remotely piloted aircraft system (RPAS) photogrammetry to resolve spatial and temporal variability of snow depth and water equivalent in a New Zealand alpine catchment is assessed in the Pisa Range, Central Otago. This approach yielded orthophotomosaics and digital surface models (DSM) at 0.05 and 0.15 m spatial resolution, respectively. An autumn reference DSM allowed mapping of winter (02/08/2016) and spring (10/09/2016) snow depth at 0.15 m spatial resolution, via DSM differencing. The consistency and accuracy of the RPAS-derived surface was assessed by comparison of snow-free regions of the spring and autumn DSMs, while accuracy of RPAS retrieved snow depth was assessed with 86 in situ snow probe measurements. Results show a mean vertical residual of 0.024 m between DSMs acquired in autumn and spring. This residual approximated a Laplace distribution, reflecting the influence of large outliers on the small overall bias. Propagation of errors associated with successive DSMs saw snow depth mapped with an accuracy of ± 0.09 m (95% c.l.). Comparing RPAS and in situ snow depth measurements revealed the influence of geo-location uncertainty and interactions between vegetation and the snowpack on snow depth uncertainty and bias. Semi-variogram analysis revealed that the RPAS outperformed systematic in situ measurements in resolving fine scale spatial variability. Despite limitations accompanying RPAS photogrammetry, this study demonstrates a repeatable means of accurately mapping snow depth for an entire, yet relatively small, hydrological basin ( 0.5 km2), at high resolution. Resolving snowpack features associated with re-distribution and preferential accumulation and ablation, snow depth maps provide geostatistically robust insights into seasonal snow processes, with unprecedented detail. Such data may enhance understanding of physical processes controlling spatial and temporal distribution of seasonal snow, and their relative importance at varying spatial and temporal scales.

  16. Comparison of subpixel image registration algorithms

    NASA Astrophysics Data System (ADS)

    Boye, R. R.; Nelson, C. L.

    2009-02-01

    Research into the use of multiframe superresolution has led to the development of algorithms for providing images with enhanced resolution using several lower resolution copies. An integral component of these algorithms is the determination of the registration of each of the low resolution images to a reference image. Without this information, no resolution enhancement can be attained. We have endeavored to find a suitable method for registering severely undersampled images by comparing several approaches. To test the algorithms, an ideal image is input to a simulated image formation program, creating several undersampled images with known geometric transformations. The registration algorithms are then applied to the set of low resolution images and the estimated registration parameters compared to the actual values. This investigation is limited to monochromatic images (extension to color images is not difficult) and only considers global geometric transformations. Each registration approach will be reviewed and evaluated with respect to the accuracy of the estimated registration parameters as well as the computational complexity required. In addition, the effects of image content, specifically spatial frequency content, as well as the immunity of the registration algorithms to noise will be discussed.

  17. SU-F-I-16: Short Breast MRI with High-Resolution T2-Weighted and Dynamic Contrast Enhanced T1-Weighted Images

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ma, J; Son, J; Arun, B

    Purpose: To develop and demonstrate a short breast (sb) MRI protocol that acquires both T2-weighted and dynamic contrast-enhanced T1-weighted images in approximately ten minutes. Methods: The sb-MRI protocol consists of two novel pulse sequences. The first is a flexible fast spin-echo triple-echo Dixon (FTED) sequence for high-resolution fat-suppressed T2-weighted imaging, and the second is a 3D fast dual-echo spoiled gradient sequence (FLEX) for volumetric fat-suppressed T1-weighted imaging before and post contrast agent injection. The flexible FTED sequence replaces each single readout during every echo-spacing period of FSE with three fast-switching bipolar readouts to produce three raw images in a singlemore » acquisition. These three raw images are then post-processed using a Dixon algorithm to generate separate water-only and fat-only images. The FLEX sequence acquires two echoes using dual-echo readout after each RF excitation and the corresponding images are post-processed using a similar Dixon algorithm to yield water-only and fat-only images. The sb-MRI protocol was implemented on a 3T MRI scanner and used for patients who had undergone concurrent clinical MRI for breast cancer screening. Results: With the same scan parameters (eg, spatial coverage, field of view, spatial and temporal resolution) as the clinical protocol, the total scan-time of the sb-MRI protocol (including the localizer, bilateral T2-weighted, and dynamic contrast-enhanced T1-weighted images) was 11 minutes. In comparison, the clinical breast MRI protocol took 43 minutes. Uniform fat suppression and high image quality were consistently achieved by sb-MRI. Conclusion: We demonstrated a sb-MRI protocol comprising both T2-weighted and dynamic contrast-enhanced T1-weighted images can be performed in approximately ten minutes. The spatial and temporal resolution of the images easily satisfies the current breast MRI accreditation guidelines by the American College of Radiology. The protocol has the potential of making breast MRI more widely accessible to and more tolerable by the patients. JMA is the inventor of United States patents that are owned by the University of Texas Board of Regents and currently licensed to GE Healthcare and Siemens Gmbh.« less

  18. The performance of the new enhanced-resolution satellite passive microwave dataset applied for snow water equivalent estimation

    NASA Astrophysics Data System (ADS)

    Pan, J.; Durand, M. T.; Jiang, L.; Liu, D.

    2017-12-01

    The newly-processed NASA MEaSures Calibrated Enhanced-Resolution Brightness Temperature (CETB) reconstructed using antenna measurement response function (MRF) is considered to have significantly improved fine-resolution measurements with better georegistration for time-series observations and equivalent field of view (FOV) for frequencies with the same monomial spatial resolution. We are looking forward to its potential for the global snow observing purposes, and therefore aim to test its performance for characterizing snow properties, especially the snow water equivalent (SWE) in large areas. In this research, two candidate SWE algorithms will be tested in China for the years between 2005 to 2010 using the reprocessed TB from the Advanced Microwave Scanning Radiometer for EOS (AMSR-E), with the results to be evaluated using the daily snow depth measurements at over 700 national synoptic stations. One of the algorithms is the SWE retrieval algorithm used for the FengYun (FY) - 3 Microwave Radiation Imager. This algorithm uses the multi-channel TB to calculate SWE for three major snow regions in China, with the coefficients adapted for different land cover types. The second algorithm is the newly-established Bayesian Algorithm for SWE Estimation with Passive Microwave measurements (BASE-PM). This algorithm uses the physically-based snow radiative transfer model to find the histogram of most-likely snow property that matches the multi-frequency TB from 10.65 to 90 GHz. It provides a rough estimation of snow depth and grain size at the same time and showed a 30 mm SWE RMS error using the ground radiometer measurements at Sodankyla. This study will be the first attempt to test it spatially for satellite. The use of this algorithm benefits from the high resolution and the spatial consistency between frequencies embedded in the new dataset. This research will answer three questions. First, to what extent can CETB increase the heterogeneity in the mapped SWE? Second, will the SWE estimation error statistics be improved using this high-resolution dataset? Third, how will the SWE retrieval accuracy be improved using CETB and the new SWE retrieval techniques?

  19. Aberration control in 4Pi nanoscopy: definitions, properties, and applications (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Hao, Xiang; Allgeyer, Edward S.; Velasco, Mary Grace M.; Booth, Martin J.; Bewersdorf, Joerg

    2016-03-01

    The development of fluorescence microscopy, which allows live-cell imaging with high labeling specificity, has made the visualization of cellular architecture routine. However, for centuries, the spatial resolution of optical microscopy was fundamentally limited by diffraction. The past two decades have seen a revolution in far-field optical nanoscopy (or "super-resolution" microscopy). The best 3D resolution is achieved by optical nanoscopes like the isoSTED or the iPALM/4Pi-SMS, which utilize two opposing objective lenses in a coherent manner. These system are, however, also more complex and the required interference conditions demand precise aberration control. Our research involves developing novel adaptive optics techniques that enable high spatial and temporal resolution imaging for biological applications. In this talk, we will discuss how adaptive optics can enhance dual-objective lens nanoscopes. We will demonstrate how adaptive optics devices provide unprecedented freedom to manipulate the light field in isoSTED nanoscopy, allow to realize automatic beam alignment, suppress the inherent side-lobes of the point-spread function, and dynamically compensate for sample-induced aberrations. We will present both the theoretical groundwork and the experimental confirmations.

  20. Image reconstruction and system modeling techniques for virtual-pinhole PET insert systems

    PubMed Central

    Keesing, Daniel B; Mathews, Aswin; Komarov, Sergey; Wu, Heyu; Song, Tae Yong; O'Sullivan, Joseph A; Tai, Yuan-Chuan

    2012-01-01

    Virtual-pinhole PET (VP-PET) imaging is a new technology in which one or more high-resolution detector modules are integrated into a conventional PET scanner with lower-resolution detectors. It can locally enhance the spatial resolution and contrast recovery near the add-on detectors, and depending on the configuration, may also increase the sensitivity of the system. This novel scanner geometry makes the reconstruction problem more challenging compared to the reconstruction of data from a standalone PET scanner, as new techniques are needed to model and account for the non-standard acquisition. In this paper, we present a general framework for fully 3D modeling of an arbitrary VP-PET insert system. The model components are incorporated into a statistical reconstruction algorithm to estimate an image from the multi-resolution data. For validation, we apply the proposed model and reconstruction approach to one of our custom-built VP-PET systems – a half-ring insert device integrated into a clinical PET/CT scanner. Details regarding the most important implementation issues are provided. We show that the proposed data model is consistent with the measured data, and that our approach can lead to reconstructions with improved spatial resolution and lesion detectability. PMID:22490983

  1. Identifying high energy density stream-reaches through refined geospatial resolution in hydropower resource assessment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pasha, M. Fayzul K.; Yang, Majntxov; Yeasmin, Dilruba

    Benefited from the rapid development of multiple geospatial data sets on topography, hydrology, and existing energy-water infrastructures, the reconnaissance level hydropower resource assessment can now be conducted using geospatial models in all regions of the US. Furthermore, the updated techniques can be used to estimate the total undeveloped hydropower potential across all regions, and may eventually help identify further hydropower opportunities that were previously overlooked. To enhance the characterization of higher energy density stream-reaches, this paper explored the sensitivity of geospatial resolution on the identification of hydropower stream-reaches using the geospatial merit matrix based hydropower resource assessment (GMM-HRA) model. GMM-HRAmore » model simulation was conducted with eight different spatial resolutions on six U.S. Geological Survey (USGS) 8-digit hydrologic units (HUC8) located at three different terrains; Flat, Mild, and Steep. The results showed that more hydropower potential from higher energy density stream-reaches can be identified with increasing spatial resolution. Both Flat and Mild terrains exhibited lower impacts compared to the Steep terrain. Consequently, greater attention should be applied when selecting the discretization resolution for hydropower resource assessments in the future study.« less

  2. Contrasting landform perception with varied radar illumination geometries and at simulated resolutions of Venera and Magellan

    NASA Technical Reports Server (NTRS)

    Ford, J. P.; Arvidson, R. E.

    1989-01-01

    The high sensitivity of imaging radars to slope at moderate to low incidence angles enhances the perception of linear topography on images. It reveals broad spatial patterns that are essential to landform mapping and interpretation. As radar responses are strongly directional, the ability to discriminate linear features on images varies with their orientation. Landforms that appear prominent on images where they are transverse to the illumination may be obscure to indistinguishable on images where they are parallel to it. Landform detection is also influenced by the spatial resolution in radar images. Seasat radar images of the Gran Desierto Dunes complex, Sonora, Mexico; the Appalachian Valley and Ridge Province; and accreted terranes in eastern interior Alaska were processed to simulate both Venera 15 and 16 images (1000 to 3000 km resolution) and image data expected from the Magellan mission (120 to 300 m resolution. The Gran Desierto Dunes are not discernable in the Venera simulation, whereas the higher resolution Magellan simulation shows dominant dune patterns produced from differential erosion of the rocks. The Magellan simulation also shows that fluvial processes have dominated erosion and exposure of the folds.

  3. Identifying high energy density stream-reaches through refined geospatial resolution in hydropower resource assessment

    DOE PAGES

    Pasha, M. Fayzul K.; Yang, Majntxov; Yeasmin, Dilruba; ...

    2016-01-07

    Benefited from the rapid development of multiple geospatial data sets on topography, hydrology, and existing energy-water infrastructures, the reconnaissance level hydropower resource assessment can now be conducted using geospatial models in all regions of the US. Furthermore, the updated techniques can be used to estimate the total undeveloped hydropower potential across all regions, and may eventually help identify further hydropower opportunities that were previously overlooked. To enhance the characterization of higher energy density stream-reaches, this paper explored the sensitivity of geospatial resolution on the identification of hydropower stream-reaches using the geospatial merit matrix based hydropower resource assessment (GMM-HRA) model. GMM-HRAmore » model simulation was conducted with eight different spatial resolutions on six U.S. Geological Survey (USGS) 8-digit hydrologic units (HUC8) located at three different terrains; Flat, Mild, and Steep. The results showed that more hydropower potential from higher energy density stream-reaches can be identified with increasing spatial resolution. Both Flat and Mild terrains exhibited lower impacts compared to the Steep terrain. Consequently, greater attention should be applied when selecting the discretization resolution for hydropower resource assessments in the future study.« less

  4. Development of new family of wide-angle anamorphic lens with controlled distortion profile

    NASA Astrophysics Data System (ADS)

    Gauvin, Jonny; Doucet, Michel; Wang, Min; Thibault, Simon; Blanc, Benjamin

    2005-08-01

    It is well known that a fish-eye lens produces a circular image of the scene with a particular distortion profile. When using a fish-eye lens with a standard sensor (e.g. 1/3", 1/4",.), only a part of the rectangular detector area is used, leaving many pixels unused. We proposed a new approach to get enhanced resolution for panoramic imaging. In this paper, various arrangements of innovative 180-degree anamorphic wide-angle lens design are considered. Their performances as well as lens manufacturability are also discussed. The concept of the design is to use anamorphic optics to produce elliptical image that maximize pixel resolution in both axis. Furthermore, a non-linear distortion profile is also introduced to enhance spatial resolution for specific field angle. Typical applications such as panoramic photography, video conferencing, and homeland/transportation security are also presented.

  5. Enhancing the isotropy of lateral resolution in coherent structured illumination microscopy

    PubMed Central

    Park, Joo Hyun; Lee, Jae Yong; Lee, Eun Seong

    2014-01-01

    We present a method to improve the isotropy of spatial resolution in a structured illumination microscopy (SIM) implemented for imaging non-fluorescent samples. To alleviate the problem of anisotropic resolution involved with the previous scheme of coherent SIM that employs the two orthogonal standing-wave illumination, referred to as the orthogonal SIM, we introduce a hexagonal-lattice illumination that incorporates three standing-wave fields simultaneously superimposed at the orientations equally divided in the lateral plane. A theoretical formulation is worked out rigorously for the coherent image formation with such a simultaneous multiple-beam illumination and an explicit Fourier-domain framework is derived for reconstructing an image with enhanced resolution. Using a computer-synthesized resolution target as a 2D coherent sample, we perform numerical simulations to examine the imaging characteristics of our three-angle SIM compared with the orthogonal SIM. The investigation on the 2D resolving power with the various test patterns of different periods and orientations reveal that the orientation-dependent undulation of lateral resolution can be reduced from 27% to 8% by using the three-angle SIM while the best resolution (0.54 times the resolution limit of conventional coherent imaging) in the directions of structured illumination is slightly deteriorated by 4.6% from that of the orthogonal SIM. PMID:24940548

  6. High spatial resolution free-breathing 3D late gadolinium enhancement cardiac magnetic resonance imaging in ischaemic and non-ischaemic cardiomyopathy: quantitative assessment of scar mass and image quality.

    PubMed

    Bizino, Maurice B; Tao, Qian; Amersfoort, Jacob; Siebelink, Hans-Marc J; van den Bogaard, Pieter J; van der Geest, Rob J; Lamb, Hildo J

    2018-04-06

    To compare breath-hold (BH) with navigated free-breathing (FB) 3D late gadolinium enhancement cardiac MRI (LGE-CMR) MATERIALS AND METHODS: Fifty-one patients were retrospectively included (34 ischaemic cardiomyopathy, 14 non-ischaemic cardiomyopathy, three discarded). BH and FB 3D phase sensitive inversion recovery sequences were performed at 3T. FB datasets were reformatted into normal resolution (FB-NR, 1.46x1.46x10mm) and high resolution (FB-HR, isotropic 0.91-mm voxels). Scar mass, scar edge sharpness (SES), SNR and CNR were compared using paired-samples t-test, Pearson correlation and Bland-Altman analysis. Scar mass was similar in BH and FB-NR (mean ± SD: 15.5±18.0 g vs. 15.5±16.9 g, p=0.997), with good correlation (r=0.953), and no bias (mean difference ± SD: 0.00±5.47 g). FB-NR significantly overestimated scar mass compared with FB-HR (15.5±16.9 g vs 14.4±15.6 g; p=0.007). FB-NR and FB-HR correlated well (r=0.988), but Bland-Altman demonstrated systematic bias (1.15±2.84 g). SES was similar in BH and FB-NR (p=0.947), but significantly higher in FB-HR than FB-NR (p<0.01). SNR and CNR were lower in BH than FB-NR (p<0.01), and lower in FB-HR than FB-NR (p<0.01). Navigated free-breathing 3D LGE-CMR allows reliable scar mass quantification comparable to breath-hold. During free-breathing, spatial resolution can be increased resulting in improved sharpness and reduced scar mass. • Navigated free-breathing 3D late gadolinium enhancement is reliable for myocardial scar quantification. • High-resolution 3D late gadolinium enhancement increases scar sharpness • Ischaemic and non-ischaemic cardiomyopathy patients can be imaged using free-breathing LGE CMR.

  7. Super-Resolution of Plant Disease Images for the Acceleration of Image-based Phenotyping and Vigor Diagnosis in Agriculture.

    PubMed

    Yamamoto, Kyosuke; Togami, Takashi; Yamaguchi, Norio

    2017-11-06

    Unmanned aerial vehicles (UAVs or drones) are a very promising branch of technology, and they have been utilized in agriculture-in cooperation with image processing technologies-for phenotyping and vigor diagnosis. One of the problems in the utilization of UAVs for agricultural purposes is the limitation in flight time. It is necessary to fly at a high altitude to capture the maximum number of plants in the limited time available, but this reduces the spatial resolution of the captured images. In this study, we applied a super-resolution method to the low-resolution images of tomato diseases to recover detailed appearances, such as lesions on plant organs. We also conducted disease classification using high-resolution, low-resolution, and super-resolution images to evaluate the effectiveness of super-resolution methods in disease classification. Our results indicated that the super-resolution method outperformed conventional image scaling methods in spatial resolution enhancement of tomato disease images. The results of disease classification showed that the accuracy attained was also better by a large margin with super-resolution images than with low-resolution images. These results indicated that our approach not only recovered the information lost in low-resolution images, but also exerted a beneficial influence on further image analysis. The proposed approach will accelerate image-based phenotyping and vigor diagnosis in the field, because it not only saves time to capture images of a crop in a cultivation field but also secures the accuracy of these images for further analysis.

  8. Super-Resolution of Plant Disease Images for the Acceleration of Image-based Phenotyping and Vigor Diagnosis in Agriculture

    PubMed Central

    Togami, Takashi; Yamaguchi, Norio

    2017-01-01

    Unmanned aerial vehicles (UAVs or drones) are a very promising branch of technology, and they have been utilized in agriculture—in cooperation with image processing technologies—for phenotyping and vigor diagnosis. One of the problems in the utilization of UAVs for agricultural purposes is the limitation in flight time. It is necessary to fly at a high altitude to capture the maximum number of plants in the limited time available, but this reduces the spatial resolution of the captured images. In this study, we applied a super-resolution method to the low-resolution images of tomato diseases to recover detailed appearances, such as lesions on plant organs. We also conducted disease classification using high-resolution, low-resolution, and super-resolution images to evaluate the effectiveness of super-resolution methods in disease classification. Our results indicated that the super-resolution method outperformed conventional image scaling methods in spatial resolution enhancement of tomato disease images. The results of disease classification showed that the accuracy attained was also better by a large margin with super-resolution images than with low-resolution images. These results indicated that our approach not only recovered the information lost in low-resolution images, but also exerted a beneficial influence on further image analysis. The proposed approach will accelerate image-based phenotyping and vigor diagnosis in the field, because it not only saves time to capture images of a crop in a cultivation field but also secures the accuracy of these images for further analysis. PMID:29113104

  9. Resolution of VTI anisotropy with elastic full-waveform inversion: theory and basic numerical examples

    NASA Astrophysics Data System (ADS)

    Podgornova, O.; Leaney, S.; Liang, L.

    2018-07-01

    Extracting medium properties from seismic data faces some limitations due to the finite frequency content of the data and restricted spatial positions of the sources and receivers. Some distributions of the medium properties make low impact on the data (including none). If these properties are used as the inversion parameters, then the inverse problem becomes overparametrized, leading to ambiguous results. We present an analysis of multiparameter resolution for the linearized inverse problem in the framework of elastic full-waveform inversion. We show that the spatial and multiparameter sensitivities are intertwined and non-sensitive properties are spatial distributions of some non-trivial combinations of the conventional elastic parameters. The analysis accounts for the Hessian information and frequency content of the data; it is semi-analytical (in some scenarios analytical), easy to interpret and enhances results of the widely used radiation pattern analysis. Single-type scattering is shown to have limited sensitivity, even for full-aperture data. Finite-frequency data lose multiparameter sensitivity at smooth and fine spatial scales. Also, we establish ways to quantify a spatial-multiparameter coupling and demonstrate that the theoretical predictions agree well with the numerical results.

  10. Resolution enhancement of pump-probe microscope with an inverse-annular filter

    NASA Astrophysics Data System (ADS)

    Kobayashi, Takayoshi; Kawasumi, Koshi; Miyazaki, Jun; Nakata, Kazuaki

    2018-04-01

    Optical pump-probe microscopy can provide images by detecting changes in probe light intensity induced by stimulated emission, photoinduced absorbance change, or photothermal-induced refractive index change in either transmission or reflection mode. Photothermal microscopy, which is one type of optical pump-probe microscopy, has intrinsically super resolution capability due to the bilinear dependence of signal intensity of pump and probe. We introduce new techniques for further resolution enhancement and fast imaging in photothermal microscope. First, we introduce a new pupil filter, an inverse-annular pupil filter in a pump-probe photothermal microscope, which provides resolution enhancement in three dimensions. The resolutions are proved to be improved in lateral and axial directions by imaging experiment using 20-nm gold nanoparticles. The improvement in X (perpendicular to the common pump and probe polarization direction), Y (parallel to the polarization direction), and Z (axial direction) are by 15 ± 6, 8 ± 8, and 21 ± 2% from the resolution without a pupil filter. The resolution enhancement is even better than the calculation using vector field, which predicts the corresponding enhancement of 11, 8, and 6%. The discussion is made to explain the unexpected results. We also demonstrate the photothermal imaging of thick biological samples (cells from rabbit intestine and kidney) stained with hematoxylin and eosin dye with the inverse-annular filter. Second, a fast, high-sensitivity photothermal microscope is developed by implementing a spatially segmented balanced detection scheme into a laser scanning microscope using a Galvano mirror. We confirm a 4.9 times improvement in signal-to-noise ratio in the spatially segmented balanced detection compared with that of conventional detection. The system demonstrates simultaneous bi-modal photothermal and confocal fluorescence imaging of transgenic mouse brain tissue with a pixel dwell time of 20 µs. The fluorescence image visualizes neurons expressing yellow fluorescence proteins, while the photothermal signal detected endogenous chromophores in the mouse brain, allowing 3D visualization of the distribution of various features such as blood cells and fine structures most probably due to lipids. This imaging modality was constructed using compact and cost-effective laser diodes, and will thus be widely useful in the life and medical sciences. Third, we have made further resolution improvement of high-sensitivity laser scanning photothermal microscopy by applying non-linear detection. By this, the new method has super resolution with 61 and 42% enhancement from the diffraction limit values of the probe and pump wavelengths, respectively, by a second-order non-linear scheme and a high-frame rate in a laser scanning microscope. The maximum resolution is determined to be 160 nm in the second-order non-linear detection mode and 270 nm in the linear detection mode by the PT signal of GNPs. The pixel rate and frame rate for 300 × 300 pixel image are 50 µs and 4.5 s, respectively. The pixel and frame rate are shorter than the rates, those are 1 ms and 100 s, using the piezo-driven stage system.

  11. Dynamic contrast-enhanced breast MRI at 7 Tesla utilizing a single-loop coil: a feasibility trial.

    PubMed

    Umutlu, Lale; Maderwald, Stefan; Kraff, Oliver; Theysohn, Jens M; Kuemmel, Sherko; Hauth, Elke A; Forsting, Michael; Antoch, Gerald; Ladd, Mark E; Quick, Harald H; Lauenstein, Thomas C

    2010-08-01

    The aim of this study was to assess the feasibility of dynamic contrast-enhanced ultra-high-field breast imaging at 7 Tesla. A total of 15 subjects, including 5 patients with histologically proven breast cancer, were examined on a 7 Tesla whole-body magnetic resonance imaging system using a unilateral linearly polarized single-loop coil. Subjects were placed in prone position on a biopsy support system, with the coil placed directly below the region of interest. The examination protocol included the following sequences: 1) T2-weighted turbo spin echo sequence; 2) six dynamic T1-weighted spoiled gradient-echo sequences; and 3) subtraction imaging. Contrast-enhanced T1-weighted imaging at 7 Tesla could be obtained at high spatial resolution with short acquisition times, providing good image accuracy and a conclusively good delineation of small anatomical and pathological structures. T2-weighted imaging could be obtained with high spatial resolution at adequate acquisition times. Because of coil limitations, four high-field magnetic resonance examinations showed decreased diagnostic value. This first scientific approach of dynamic contrast-enhanced breast magnetic resonance imaging at 7 Tesla demonstrates the complexity of ultra-high-field breast magnetic resonance imaging and countenances the implementation of further advanced bilateral coil concepts to circumvent current limitations from the coil and ultra-high-field magnetic strength. 2010 AUR. Published by Elsevier Inc. All rights reserved.

  12. Spectro-spatial relationship between UAV derived high resolution DEM and SWIR hyperspectral data: application to an ombrotrophic peatland

    NASA Astrophysics Data System (ADS)

    Arroyo-Mora, J. Pablo; Kalacska, Margaret; Lucanus, Oliver; Soffer, Raymond; Leblanc, George

    2017-10-01

    Peatlands cover 3% of the globe and are key ecosystems for climate regulation. To better understand the potential effects of climate change in peatlands, a major challenge is to determine the complex relationship between hydrology, microtopography, vegetation patterns, and gas exchange. Here we study the spectral and spatial relationship of microtopographic features (e.g. hollows and hummocks) and near-surface water through narrow-band spectral indices derived from hyperspectral imagery. We used a very high resolution digital elevation model (2.5 cm horizontal, 2.2 cm vertical resolution) derived from an UAV based Structure from Motion photogrammetry to map hollows and hummocks in the peatland area. We also created a 2 cm spatial resolution orthophoto mosaic to enhance the visual identification of these hollows and hummocks. Furthermore, we collected SWIR airborne hyperspectral (880-2450 nm) imagery at 1 m pixel resolution over four time periods, from April to June 2016 (phenological gradient: vegetation greening). Our results revealed an increase in the water indices values (NDWI1640 and NDWI2130) and a decrease in the moisture stress index (MSI) between April and June. In addition, for the same period the NDWI2130 shows a bimodal distribution indicating potential to quantitatively assess moisture differences between mosses and vascular plants. Our results, using the digital surface model to extract NDWI2130 values, showed significant differences between hollows and hummocks for each time period, with higher moisture values for hollows (i.e. moss dominated). However, for June, the water index for hummocks approximated the values found in hollows. Our study shows the advantages of using fine spatial and spectral scales to detect temporal trends in near surface water in a peatland.

  13. Elevation-dependent warming in global climate model simulations at high spatial resolution

    NASA Astrophysics Data System (ADS)

    Palazzi, Elisa; Mortarini, Luca; Terzago, Silvia; von Hardenberg, Jost

    2018-06-01

    The enhancement of warming rates with elevation, so-called elevation-dependent warming (EDW), is one of the regional, still not completely understood, expressions of global warming. Sentinels of climate and environmental changes, mountains have experienced more rapid and intense warming trends in the recent decades, leading to serious impacts on mountain ecosystems and downstream. In this paper we use a state-of-the-art Global Climate Model (EC-Earth) to investigate the impact of model spatial resolution on the representation of this phenomenon and to highlight possible differences in EDW and its causes in different mountain regions of the Northern Hemisphere. To this end we use EC-Earth climate simulations at five different spatial resolutions, from ˜ 125 to ˜ 16 km, to explore the existence and the driving mechanisms of EDW in the Colorado Rocky Mountains, the Greater Alpine Region and the Tibetan Plateau-Himalayas. Our results show that the more frequent EDW drivers in all regions and seasons are the changes in albedo and in downward thermal radiation and this is reflected in both daytime and nighttime warming. In the Tibetan Plateau-Himalayas and in the Greater Alpine Region, an additional driver is the change in specific humidity. We also find that, while generally the model shows no clear resolution dependence in its ability to simulate the existence of EDW in the different regions, specific EDW characteristics such as its intensity and the relative role of different driving mechanisms may be different in simulations performed at different spatial resolutions. Moreover, we find that the role of internal climate variability can be significant in modulating the EDW signal, as suggested by the spread found in the multi-member ensemble of the EC-Earth experiments which we use.

  14. Enhanced Deforestation Mapping in North Korea using Spatial-temporal Image Fusion Method and Phenology-based Index

    NASA Astrophysics Data System (ADS)

    Jin, Y.; Lee, D.

    2017-12-01

    North Korea (the Democratic People's Republic of Korea, DPRK) is known to have some of the most degraded forest in the world. The characteristics of forest landscape in North Korea is complex and heterogeneous, the major vegetation cover types in the forest are hillside farm, unstocked forest, natural forest, and plateau vegetation. Better classification of types in high spatial resolution of deforested areas could provide essential information for decisions about forest management priorities and restoration of deforested areas. For mapping heterogeneous vegetation covers, the phenology-based indices are helpful to overcome the reflectance value confusion that occurs when using one season images. Coarse spatial resolution images may be acquired with a high repetition rate and it is useful for analyzing phenology characteristics, but may not capture the spatial detail of the land cover mosaic of the region of interest. Previous spatial-temporal fusion methods were only capture the temporal change, or focused on both temporal change and spatial change but with low accuracy in heterogeneous landscapes and small patches. In this study, a new concept for spatial-temporal image fusion method focus on heterogeneous landscape was proposed to produce fine resolution images at both fine spatial and temporal resolution. We classified the three types of pixels between the base image and target image, the first type is only reflectance changed caused by phenology, this type of pixels supply the reflectance, shape and texture information; the second type is both reflectance and spectrum changed in some bands caused by phenology like rice paddy or farmland, this type of pixels only supply shape and texture information; the third type is reflectance and spectrum changed caused by land cover type change, this type of pixels don't provide any information because we can't know how land cover changed in target image; and each type of pixels were applied different prediction methods. Results show that both STARFM and FSDAF predicted in low accuracy in second type pixels and small patches. Classification results used spatial-temporal image fusion method proposed in this study showed overall classification accuracy of 89.38%, with corresponding kappa coefficients of 0.87.

  15. Relativistic electron flux comparisons at low and high altitudes with fast time resolution and broad spatial coverage

    NASA Technical Reports Server (NTRS)

    Imhof, W. L.; Gaines, E. E.; Mcglennon, J. P.; Baker, D. N.; Reeves, G. D.; Belian, R. D.

    1994-01-01

    Analyses are presented for the first high-time resolution multisatellite study of the spatial and temporal characteristics of a relativistic electron enhancement event with a rapid onset. Measurements of MeV electrons were made from two low-altitude polar orbiting satellites and three spacecraft at synchronous altitude. The electron fluxes observed by the low-altitude satellites include precipitating electrons in both the bounce and drift loss cones as well as electrons that are stably trapped, whereas the observations at geosynchronous altitude are dominated by the trapped population. The fluxes of greater than 1 MeV electrons at low-satellite altitude over a wide range of L shells tracked very well the fluxes greater than 0.93 MeV at synchronous altitude.

  16. High Spatial and Temporal Resolution Dynamic Contrast-Enhanced Magnetic Resonance Angiography (CE-MRA) using Compressed Sensing with Magnitude Image Subtraction

    PubMed Central

    Rapacchi, Stanislas; Han, Fei; Natsuaki, Yutaka; Kroeker, Randall; Plotnik, Adam; Lehman, Evan; Sayre, James; Laub, Gerhard; Finn, J Paul; Hu, Peng

    2014-01-01

    Purpose We propose a compressed-sensing (CS) technique based on magnitude image subtraction for high spatial and temporal resolution dynamic contrast-enhanced MR angiography (CE-MRA). Methods Our technique integrates the magnitude difference image into the CS reconstruction to promote subtraction sparsity. Fully sampled Cartesian 3D CE-MRA datasets from 6 volunteers were retrospectively under-sampled and three reconstruction strategies were evaluated: k-space subtraction CS, independent CS, and magnitude subtraction CS. The techniques were compared in image quality (vessel delineation, image artifacts, and noise) and image reconstruction error. Our CS technique was further tested on 7 volunteers using a prospectively under-sampled CE-MRA sequence. Results Compared with k-space subtraction and independent CS, our magnitude subtraction CS provides significantly better vessel delineation and less noise at 4X acceleration, and significantly less reconstruction error at 4X and 8X (p<0.05 for all). On a 1–4 point image quality scale in vessel delineation, our technique scored 3.8±0.4 at 4X, 2.8±0.4 at 8X and 2.3±0.6 at 12X acceleration. Using our CS sequence at 12X acceleration, we were able to acquire dynamic CE-MRA with higher spatial and temporal resolution than current clinical TWIST protocol while maintaining comparable image quality (2.8±0.5 vs. 3.0±0.4, p=NS). Conclusion Our technique is promising for dynamic CE-MRA. PMID:23801456

  17. Filling the gap: using non-invasive geophysical methods to monitor the processes leading to enhanced carbon turnover induced by periodic water table fluctuations

    NASA Astrophysics Data System (ADS)

    Mellage, A.; Pronk, G.; Atekwana, E. A.; Furman, A.; Rezanezhad, F.; Van Cappellen, P.

    2017-12-01

    Subsurface transition environments such as the capillary fringe are characterized by steep gradients in redox conditions. Spatial and temporal variations in electron acceptor and donor availability - driven by hydrological changes - may enhance carbon turnover, in some cases resulting in pulses of CO2-respiration. Filling the mechanistic knowledge gap between the hydrological driver and its biogeochemical effects hinges on our ability to monitor microbial activity and key geochemical markers at a high spatial and temporal resolution. However, direct access to subsurface biogeochemical processes is logistically difficult, invasive and usually expensive. In-line, non-invasive geophysical techniques - Spectral Induced Polarization (SIP) and Electrodic Potential (EP), specifically - offer a comparatively inexpensive alternative and can provide data with high spatial and temporal resolution. The challenge lies in linking electrical responses to specific changes in biogeochemical processes. We conducted SIP and EP measurements on a soil column experiment where an artificial soil mixture was subjected to monthly drainage and imbibition cycles. SIP responses showed a clear dependence on redox zonation and microbial abundance. Temporally variable responses exhibited no direct moisture dependence suggesting that the measured responses recorded changes in microbial activity and coincided with the depth interval over which enhanced carbon turnover was observed. EP measurements detected the onset of sulfate mineralization and mapped its depth zonation. SIP and EP signals thus detected enhanced microbial activity within the water table fluctuation zone as well as the timing of the development of specific reactive processes. These findings can be used to relate measured electrical signals to specific reaction pathways and help inform reactive transport models, increasing their predictive capabilities.

  18. Enhanced spatial resolution in fluorescence molecular tomography using restarted L1-regularized nonlinear conjugate gradient algorithm.

    PubMed

    Shi, Junwei; Liu, Fei; Zhang, Guanglei; Luo, Jianwen; Bai, Jing

    2014-04-01

    Owing to the high degree of scattering of light through tissues, the ill-posedness of fluorescence molecular tomography (FMT) inverse problem causes relatively low spatial resolution in the reconstruction results. Unlike L2 regularization, L1 regularization can preserve the details and reduce the noise effectively. Reconstruction is obtained through a restarted L1 regularization-based nonlinear conjugate gradient (re-L1-NCG) algorithm, which has been proven to be able to increase the computational speed with low memory consumption. The algorithm consists of inner and outer iterations. In the inner iteration, L1-NCG is used to obtain the L1-regularized results. In the outer iteration, the restarted strategy is used to increase the convergence speed of L1-NCG. To demonstrate the performance of re-L1-NCG in terms of spatial resolution, simulation and physical phantom studies with fluorescent targets located with different edge-to-edge distances were carried out. The reconstruction results show that the re-L1-NCG algorithm has the ability to resolve targets with an edge-to-edge distance of 0.1 cm at a depth of 1.5 cm, which is a significant improvement for FMT.

  19. High-resolution Monthly Satellite Precipitation Product over the Conterminous United States

    NASA Astrophysics Data System (ADS)

    Hashemi, H.; Fayne, J.; Knight, R. J.; Lakshmi, V.

    2017-12-01

    We present a data set that enhanced the Tropical Rainfall Measuring Mission (TRMM) Multi-satellite Precipitation Analysis (TMPA) monthly product 3B43 in its accuracy and spatial resolution. For this, we developed a correction function to improve the accuracy of TRMM 3B43, spatial resolution of 25 km, by estimating and removing the bias in the satellite data using a ground-based precipitation data set. We observed a strong relationship between the bias and land surface elevation; TRMM 3B43 tends to underestimate the ground-based product at elevations above 1500 m above mean sea level (m.amsl) over the conterminous United States. A relationship was developed between satellite bias and elevation. We then resampled TRMM 3B43 to the Digital Elevation Model (DEM) data set at a spatial resolution of 30 arc second ( 1 km on the ground). The produced high-resolution satellite-based data set was corrected using the developed correction function based on the bias-elevation relationship. Assuming that each rain gauge represents an area of 1 km2, we verified our product against 9,200 rain gauges across the conterminous United States. The new product was compared with the gauges, which have 50, 60, 70, 80, 90, and 100% temporal coverage within the TRMM period of 1998 to 2015. Comparisons between the high-resolution corrected satellite-based data and gauges showed an excellent agreement. The new product captured more detail in the changes in precipitation over the mountainous region than the original TRMM 3B43.

  20. Multicolor Super-Resolution Fluorescence Imaging via Multi-Parameter Fluorophore Detection

    PubMed Central

    Bates, Mark; Dempsey, Graham T; Chen, Kok Hao; Zhuang, Xiaowei

    2012-01-01

    Understanding the complexity of the cellular environment will benefit from the ability to unambiguously resolve multiple cellular components, simultaneously and with nanometer-scale spatial resolution. Multicolor super-resolution fluorescence microscopy techniques have been developed to achieve this goal, yet challenges remain in terms of the number of targets that can be simultaneously imaged and the crosstalk between color channels. Herein, we demonstrate multicolor stochastic optical reconstruction microscopy (STORM) based on a multi-parameter detection strategy, which uses both the fluorescence activation wavelength and the emission color to discriminate between photo-activatable fluorescent probes. First, we obtained two-color super-resolution images using the near-infrared cyanine dye Alexa 750 in conjunction with a red cyanine dye Alexa 647, and quantified color crosstalk levels and image registration accuracy. Combinatorial pairing of these two switchable dyes with fluorophores which enhance photo-activation enabled multi-parameter detection of six different probes. Using this approach, we obtained six-color super-resolution fluorescence images of a model sample. The combination of multiple fluorescence detection parameters for improved fluorophore discrimination promises to substantially enhance our ability to visualize multiple cellular targets with sub-diffraction-limit resolution. PMID:22213647

  1. The effects of climate change and extreme wildfire events on runoff erosion over a mountain watershed

    Treesearch

    Mingliang Liu; Michael E. Barber; Keith A. Cherkauer; Pete Robichaud; Jennifer C. Adam

    2016-01-01

    Increases in wildfire occurrence and severity under an altered climate can substantially impact terrestrial ecosystems through enhancing runoff erosion. Improved prediction tools that provide high resolution spatial information are necessary for location-specific soil conservation and watershed management. However, quantifying the magnitude of soil erosion and...

  2. Space telescope searches for black holes in galactic nuclei

    NASA Technical Reports Server (NTRS)

    Harms, Richard J.

    1989-01-01

    The Hubble Space Telescope (HST) will allow astronomers to obtain luminosity profiles, rotation curves, and velocity dispersions at angular scales that are an order of magnitude superior to those obtained previously. This enhanced spatial resolution will greatly improve the sensitivity for detecting centrally condensed matter in nearby galactic nuclei including, possibly, black holes.

  3. An assessment of the differences between spatial resolution and grid size for the SMAP enhanced soil moisture product over homogeneous sites

    USDA-ARS?s Scientific Manuscript database

    Satellite-based passive microwave remote sensing typically involves a scanning antenna that makes measurements at irregularly spaced locations. These locations can change on a day to day basis. Soil moisture products derived from satellite-based passive microwave remote sensing are usually resampled...

  4. Principle, system, and applications of tip-enhanced Raman spectroscopy

    NASA Astrophysics Data System (ADS)

    Zhang, MingQian; Wang, Rui; Wu, XiaoBin; Wang, Jia

    2012-08-01

    Raman spectroscopy is a powerful technique in chemical information characterization. However, this spectral method is subject to two obstacles in nano-material detection. One is diffraction limited spatial resolution, and the other is its inherent small Raman cross section and weak signaling. To resolve these problems, a new approach has been developed, denoted as tip-enhanced Raman spectroscopy (TERS). TERS is capable of high-resolution and high-sensitivity detection and demonstrated to be a promising spectroscopic and micro-topographic method to characterize nano-materials and nanostructures. In this paper, the principle and experimental system of TERS are discussed. The latest application of TERS in molecule detection, biological specimen identification, nanao-material characterization, and semi-conductor material determination with some specific experimental examples are presented.

  5. ALMA Discovery of Solar Umbral Brightness Enhancement at λ = 3 mm

    NASA Astrophysics Data System (ADS)

    Iwai, K.; Loukitcheva, M.; Shimojo, M.; Solanki, S. K.; White, S. M.

    2017-12-01

    We report the discovery of a brightness enhancement in the center of a large sunspot umbra at a wavelength of 3 mm using the Atacama Large Millimeter/sub-millimeter Array (ALMA). Sunspots are among the most prominent features on the solar surface, but many of their aspects are surprisingly poorly understood. We analyzed a λ = 3 mm (100 GHz) mosaic image obtained by ALMA that includes a large sunspot within the active region AR12470, on 2015 December 16. The 3 mm map has a 300''×300'' field of view and 4.9''×2.2'' spatial resolution, which is the highest spatial resolution map of an entire sunspot in this frequency range. We find a gradient of 3 mm brightness from a high value in the outer penumbra to a low value in the inner penumbra/outer umbra. Within the inner umbra, there is a marked increase in 3 mm brightness temperature, which we call an umbral brightness enhancement. This enhanced emission corresponds to a temperature excess of 800 K relative to the surrounding inner penumbral region and coincides with excess brightness in the 1330 and 1400 Å slit-jaw images of the Interface Region Imaging Spectrograph (IRIS), adjacent to a partial lightbridge. This λ = 3 mm brightness enhancement may be an intrinsic feature of the sunspot umbra at chromospheric heights, such as a manifestation of umbral flashes, or it could be related to a coronal plume, since the brightness enhancement was coincident with the footpoint of a coronal loop observed at 171 Å.

  6. Joint Estimation of Effective Brain Wave Activation Modes Using EEG/MEG Sensor Arrays and Multimodal MRI Volumes.

    PubMed

    Galinsky, Vitaly L; Martinez, Antigona; Paulus, Martin P; Frank, Lawrence R

    2018-04-13

    In this letter, we present a new method for integration of sensor-based multifrequency bands of electroencephalography and magnetoencephalography data sets into a voxel-based structural-temporal magnetic resonance imaging analysis by utilizing the general joint estimation using entropy regularization (JESTER) framework. This allows enhancement of the spatial-temporal localization of brain function and the ability to relate it to morphological features and structural connectivity. This method has broad implications for both basic neuroscience research and clinical neuroscience focused on identifying disease-relevant biomarkers by enhancing the spatial-temporal resolution of the estimates derived from current neuroimaging modalities, thereby providing a better picture of the normal human brain in basic neuroimaging experiments and variations associated with disease states.

  7. Acoustic methods for cavitation mapping in biomedical applications

    NASA Astrophysics Data System (ADS)

    Wan, M.; Xu, S.; Ding, T.; Hu, H.; Liu, R.; Bai, C.; Lu, S.

    2015-12-01

    In recent years, cavitation is increasingly utilized in a wide range of applications in biomedical field. Monitoring the spatial-temporal evolution of cavitation bubbles is of great significance for efficiency and safety in biomedical applications. In this paper, several acoustic methods for cavitation mapping proposed or modified on the basis of existing work will be presented. The proposed novel ultrasound line-by-line/plane-by-plane method can depict cavitation bubbles distribution with high spatial and temporal resolution and may be developed as a potential standard 2D/3D cavitation field mapping method. The modified ultrafast active cavitation mapping based upon plane wave transmission and reception as well as bubble wavelet and pulse inversion technique can apparently enhance the cavitation to tissue ratio in tissue and further assist in monitoring the cavitation mediated therapy with good spatial and temporal resolution. The methods presented in this paper will be a foundation to promote the research and development of cavitation imaging in non-transparent medium.

  8. A Unified Fisher's Ratio Learning Method for Spatial Filter Optimization.

    PubMed

    Li, Xinyang; Guan, Cuntai; Zhang, Haihong; Ang, Kai Keng

    To detect the mental task of interest, spatial filtering has been widely used to enhance the spatial resolution of electroencephalography (EEG). However, the effectiveness of spatial filtering is undermined due to the significant nonstationarity of EEG. Based on regularization, most of the conventional stationary spatial filter design methods address the nonstationarity at the cost of the interclass discrimination. Moreover, spatial filter optimization is inconsistent with feature extraction when EEG covariance matrices could not be jointly diagonalized due to the regularization. In this paper, we propose a novel framework for a spatial filter design. With Fisher's ratio in feature space directly used as the objective function, the spatial filter optimization is unified with feature extraction. Given its ratio form, the selection of the regularization parameter could be avoided. We evaluate the proposed method on a binary motor imagery data set of 16 subjects, who performed the calibration and test sessions on different days. The experimental results show that the proposed method yields improvement in classification performance for both single broadband and filter bank settings compared with conventional nonunified methods. We also provide a systematic attempt to compare different objective functions in modeling data nonstationarity with simulation studies.To detect the mental task of interest, spatial filtering has been widely used to enhance the spatial resolution of electroencephalography (EEG). However, the effectiveness of spatial filtering is undermined due to the significant nonstationarity of EEG. Based on regularization, most of the conventional stationary spatial filter design methods address the nonstationarity at the cost of the interclass discrimination. Moreover, spatial filter optimization is inconsistent with feature extraction when EEG covariance matrices could not be jointly diagonalized due to the regularization. In this paper, we propose a novel framework for a spatial filter design. With Fisher's ratio in feature space directly used as the objective function, the spatial filter optimization is unified with feature extraction. Given its ratio form, the selection of the regularization parameter could be avoided. We evaluate the proposed method on a binary motor imagery data set of 16 subjects, who performed the calibration and test sessions on different days. The experimental results show that the proposed method yields improvement in classification performance for both single broadband and filter bank settings compared with conventional nonunified methods. We also provide a systematic attempt to compare different objective functions in modeling data nonstationarity with simulation studies.

  9. Myocardial perfusion MRI with sliding-window conjugate-gradient HYPR.

    PubMed

    Ge, Lan; Kino, Aya; Griswold, Mark; Mistretta, Charles; Carr, James C; Li, Debiao

    2009-10-01

    First-pass perfusion MRI is a promising technique for detecting ischemic heart disease. However, the diagnostic value of the method is limited by the low spatial coverage, resolution, signal-to-noise ratio (SNR), and cardiac motion-related image artifacts. In this study we investigated the feasibility of using a method that combines sliding window and CG-HYPR methods (SW-CG-HYPR) to reduce the acquisition window for each slice while maintaining the temporal resolution of one frame per heartbeat in myocardial perfusion MRI. This method allows an increased number of slices, reduced motion artifacts, and preserves the relatively high SNR and spatial resolution of the "composite images." Results from eight volunteers demonstrate the feasibility of SW-CG-HYPR for accelerated myocardial perfusion imaging with accurate signal intensity changes of left ventricle blood pool and myocardium. Using this method the acquisition time per cardiac cycle was reduced by a factor of 4 and the number of slices was increased from 3 to 8 as compared to the conventional technique. The SNR of the myocardium at peak enhancement with SW-CG-HYPR (13.83 +/- 2.60) was significantly higher (P < 0.05) than the conventional turbo-FLASH protocol (8.40 +/- 1.62). Also, the spatial resolution of the myocardial perfection images was significantly improved. SW-CG-HYPR is a promising technique for myocardial perfusion MRI. (c) 2009 Wiley-Liss, Inc.

  10. Resolution and quantification accuracy enhancement of functional delay and sum beamforming for three-dimensional acoustic source identification with solid spherical arrays

    NASA Astrophysics Data System (ADS)

    Chu, Zhigang; Yang, Yang; Shen, Linbang

    2017-05-01

    Functional delay and sum (FDAS) is a novel beamforming algorithm introduced for the three-dimensional (3D) acoustic source identification with solid spherical microphone arrays. Being capable of offering significantly attenuated sidelobes with a fast speed, the algorithm promises to play an important role in interior acoustic source identification. However, it presents some intrinsic imperfections, specifically poor spatial resolution and low quantification accuracy. This paper focuses on conquering these imperfections by ridge detection (RD) and deconvolution approach for the mapping of acoustic sources (DAMAS). The suggested methods are referred to as FDAS+RD and FDAS+RD+DAMAS. Both computer simulations and experiments are utilized to validate their effects. Several interesting conclusions have emerged: (1) FDAS+RD and FDAS+RD+DAMAS both can dramatically ameliorate FDAS's spatial resolution and at the same time inherit its advantages. (2) Compared to the conventional DAMAS, FDAS+RD+DAMAS enjoys the same super spatial resolution, stronger sidelobe attenuation capability and more than two hundred times faster speed. (3) FDAS+RD+DAMAS can effectively conquer FDAS's low quantification accuracy. Whether the focus distance is equal to the distance from the source to the array center or not, it can quantify the source average pressure contribution accurately. This study will be of great significance to the accurate and quick localization and quantification of acoustic sources in cabin environments.

  11. The Feasibility of Conformal Thermal Therapy with Transurethral Ultrasound Heating Applicators and MR Temperature Feedback

    NASA Astrophysics Data System (ADS)

    Choy, Vanessa; Tang, Kee; Wachsmuth, Jeff; Chopra, Rajiv; Bronskill, Michael

    2006-05-01

    Transurethral thermal therapy offers a minimally invasive alternative for the treatment of prostate diseases including benign prostate hyperplasia (BPH) and prostate cancer. Accurate heating of a targeted region of the gland can be achieved through the use of a rotating directional heating source incorporating planar ultrasound transducers, and the implementation of active temperature feedback along the beam direction during heating provided by magnetic resonance (MR) thermometry. The performance of this control method with practical spatial, temporal, and temperature resolution (such as angular alignment, spatial resolution, update rate for temperature feedback (imaging time), and the presence of noise) for thermal feedback using a clinical 1.5 T MR scanner was investigated in simulations. As expected, the control algorithm was most sensitive to the presence of noise, with noticeable degradation in its performance above ±2°C of temperature uncertainty. With respect to temporal resolution, acceptable performance was achieved at update rates of 5s or faster. The control algorithm was relatively insensitive to reduced spatial resolution due to the broad nature of the heating pattern produced by the heating applicator, this provides an opportunity to improve signal-to-noise ratio (SNR). The overall simulation results confirm that existing clinical 1.5T MR imagers are capable of providing adequate temperature feedback for transurethral thermal therapy without special pulse sequences or enhanced imaging hardware.

  12. Mapping plastic greenhouse with medium spatial resolution satellite data: Development of a new spectral index

    NASA Astrophysics Data System (ADS)

    Yang, Dedi; Chen, Jin; Zhou, Yuan; Chen, Xiang; Chen, Xuehong; Cao, Xin

    2017-06-01

    Plastic greenhouses (PGs) are an important agriculture development technique to protect and control the growing environment for food crops. The extensive use of PGs can change the agriculture landscape and affects the local environment. Accurately mapping and estimating the coverage of PGs is a necessity to the strategic planning of modern agriculture. Unfortunately, PG mapping over large areas is methodologically challenging, as the medium spatial resolution satellite imagery (such as Landsat data) used for analysis lacks spatial details and spectral variations. To fill the gap, the paper proposes a new plastic greenhouse index (PGI) based on the spectral, sensitivity, and separability analysis of PGs using medium spatial resolution images. In the context of the Landsat Enhanced Thematic Mapper Plus (ETM+) imagery, the paper examines the effectiveness and capability of the proposed PGI. The results indicate that PGs in Landsat ETM+ image can be successfully detected by the PGI if the PG fraction is greater than 12% in a mixed pixel. A kappa coefficient of 0.83 and overall accuracy of 91.2% were achieved when applying the proposed PGI in the case of Weifang District, Shandong, China. These results show that the proposed index can be applied to identifying transparent PGs in atmospheric corrected Landsat image and has the potential for the digital mapping of plastic greenhouse coverage over a large area.

  13. A Nanoplasmonic Strategy for Precision in-situ Measurements of Tip-enhanced Raman and Fluorescence Spectroscopy

    PubMed Central

    Meng, Lingyan; Sun, Mengtao; Chen, Jianing; Yang, Zhilin

    2016-01-01

    We theoretically investigate an optimized tip-film system that supports in-situ measurement of tip-enhanced Raman spectroscopy (TERS) and tip-enhanced fluorescence (TEF) of dye molecules. A scanning tunneling microscope (STM) is proposed to precisely control the tip-film distance, and thus in-situ measurement of TERS and TEF can be realized utilizing the specific surface plasmon resonance (SPR) properties of the tip-film system. Our calculations show that the optimized tip-film distance of 2 nm suggests a possibility of efficient acquisition of TERS and TEF in-situ. The calculated spatial resolution of TERS and spectral resolution of TEF can be down to 6.5 nm and 10 nm, respectively. Our theoretical results may find promising application in developing multiple functional nano-spectroscopy through which Raman and fluorescence can be measured in-situ at the nanoscale level. PMID:26780882

  14. Higher sensitivity secondary ion mass spectrometry of biological molecules for high resolution, chemically specific imaging.

    PubMed

    McDonnell, Liam A; Heeren, Ron M A; de Lange, Robert P J; Fletcher, Ian W

    2006-09-01

    To expand the role of high spatial resolution secondary ion mass spectrometry (SIMS) in biological studies, numerous developments have been reported in recent years for enhancing the molecular ion yield of high mass molecules. These include both surface modification, including matrix-enhanced SIMS and metal-assisted SIMS, and polyatomic primary ions. Using rat brain tissue sections and a bismuth primary ion gun able to produce atomic and polyatomic primary ions, we report here how the sensitivity enhancements provided by these developments are additive. Combined surface modification and polyatomic primary ions provided approximately 15.8 times more signal than using atomic primary ions on the raw sample, whereas surface modification and polyatomic primary ions yield approximately 3.8 and approximately 8.4 times more signal. This higher sensitivity is used to generate chemically specific images of higher mass biomolecules using a single molecular ion peak.

  15. 3.0-T functional brain imaging: a 5-year experience.

    PubMed

    Scarabino, T; Giannatempo, G M; Popolizio, T; Tosetti, M; d'Alesio, V; Esposito, F; Di Salle, F; Di Costanzo, A; Bertolino, A; Maggialetti, A; Salvolini, U

    2007-02-01

    The aim of this paper is to illustrate the technical, methodological and diagnostic features of functional imaging (comprising spectroscopy, diffusion, perfusion and cortical activation techniques) and its principal neuroradiological applications on the basis of the experience gained by the authors in the 5 years since the installation of a high-field magnetic resonance (MR) magnet. These MR techniques are particularly effective at 3.0 Tesla (T) owing to their high signal, resolution and sensitivity, reduced scanning times and overall improved diagnostic ability. In particular, the high-field strength enhances spectroscopic analysis due to a greater signal-to-noise ratio (SNR) and improved spectral, space and time resolution, resulting in the ability to obtain high-resolution spectroscopic studies not only of the more common metabolites, but also--and especially--of those which, due to their smaller concentrations, are difficult to detect using 1.5-T systems. All of these advantages can be obtained with reduced acquisition times. In diffusion studies, the high-field strength results in greater SNR, because 3.0-T magnets enable increased spatial resolution, which enhances accuracy. They also allow exploration in greater detail of more complex phenomena (such as diffusion tensor and tractography), which are not clearly depicted on 1.5-T systems. The most common perfusion study (with intravenous injection of a contrast agent) benefits from the greater SNR and higher magnetic susceptibility by achieving dramatically improved signal changes, and thus greater reliability, using smaller doses of contrast agent. Functional MR imaging (fMRI) is without doubt the modality in which high-field strength has had the greatest impact. Images acquired with the blood-oxygen-level-dependent (BOLD) technique benefit from the greater SNR afforded by 3.0-T magnets and from their stronger magnetic susceptibility effects, providing higher signal and spatial resolution. This enhances reliability of the localisation of brain functions, making it possible to map additional areas, even in the millimetre and submillimetre scale. The data presented and results obtained to date show that 3.0-T morphofunctional imaging can become the standard for high-resolution investigation of brain disease.

  16. Spatial super-resolution of colored images by micro mirrors

    NASA Astrophysics Data System (ADS)

    Dahan, Daniel; Yaacobi, Ami; Pinsky, Ephraim; Zalevsky, Zeev

    2018-06-01

    In this paper, we present two methods of dealing with the geometric resolution limit of color imaging sensors. It is possible to overcome the pixel size limit by adding a digital micro-mirror device component on the intermediate image plane of an optical system, and adapting its pattern in a computerized manner before sampling each frame. The full RGB image can be reconstructed from the Bayer camera by building a dedicated optical design, or by adjusting the demosaicing process to the special format of the enhanced image.

  17. A scheme for lensless X-ray microscopy combining coherent diffraction imaging and differential corner holography.

    PubMed

    Capotondi, F; Pedersoli, E; Kiskinova, M; Martin, A V; Barthelmess, M; Chapman, H N

    2012-10-22

    We successfully use the corners of a common silicon nitride supporting window in lensless X-ray microscopy as extended references in differential holography to obtain a real space hologram of the illuminated object. Moreover, we combine this method with the iterative phasing techniques of coherent diffraction imaging to enhance the spatial resolution on the reconstructed object, and overcome the problem of missing areas in the collected data due to the presence of a beam stop, achieving a resolution close to 85 nm.

  18. Optimization of the Performance of Segmented Scintillators for Radiotherapy Imaging through Novel Binning Techniques

    PubMed Central

    El-Mohri, Youcef; Antonuk, Larry E.; Choroszucha, Richard B.; Zhao, Qihua; Jiang, Hao; Liu, Langechuan

    2014-01-01

    Thick, segmented crystalline scintillators have shown increasing promise as replacement x-ray converters for the phosphor screens currently used in active matrix flat-panel imagers (AMFPIs) in radiotherapy, by virtue of providing over an order of magnitude improvement in the DQE. However, element-to-element misalignment in current segmented scintillator prototypes creates a challenge for optimal registration with underlying AMFPI arrays, resulting in degradation of spatial resolution. To overcome this challenge, a methodology involving the use of a relatively high resolution AMFPI array in combination with novel binning techniques is presented. The array, which has a pixel pitch of 0.127 mm, was coupled to prototype segmented scintillators based on BGO, LYSO and CsI:Tl materials, each having a nominal element-to-element pitch of 1.016 mm and thickness of ~1 cm. The AMFPI systems incorporating these prototypes were characterized at a radiotherapy energy of 6 MV in terms of MTF, NPS, DQE, and reconstructed images of a resolution phantom acquired using a cone-beam CT geometry. For each prototype, the application of 8×8 pixel binning to achieve a sampling pitch of 1.016 mm was optimized through use of an alignment metric which minimized misregistration and thereby improved spatial resolution. In addition, the application of alternative binning techniques that exclude the collection of signal near septal walls resulted in further significant improvement in spatial resolution for the BGO and LYSO prototypes, though not for the CsI:Tl prototype due to the large amount of optical cross-talk resulting from significant light spread between scintillator elements in that device. The efficacy of these techniques for improving spatial resolution appears to be enhanced for scintillator materials that exhibit mechanical hardness, high density and high refractive index, such as BGO. Moreover, materials that exhibit these properties as well as offer significantly higher light output than BGO, such as CdWO4, should provide the additional benefit of preserving DQE performance. PMID:24487347

  19. SYMPOSIUM ON MULTIMODALITY CARDIOVASCULAR MOLECULAR IMAGING IMAGING TECHNOLOGY - PART 2

    PubMed Central

    de Kemp, Robert A.; Epstein, Frederick H.; Catana, Ciprian; Tsui, Benjamin M.W.; Ritman, Erik L.

    2013-01-01

    Rationale The ability to trace or identify specific molecules within a specific anatomic location provides insight into metabolic pathways, tissue components and tracing of solute transport mechanisms. With the increasing use of small animals for research such imaging must have sufficiently high spatial resolution to allow anatomic localization as well as sufficient specificity and sensitivity to provide an accurate description of the molecular distribution and concentration. Methods Imaging methods based on electromagnetic radiation, such as PET, SPECT, MRI and CT, are increasingly applicable due to recent advances in novel scanner hardware, image reconstruction software and availability of novel molecules which have enhanced sensitivity in these methodologies. Results Micro-PET has been advanced by development of detector arrays that provide higher resolution and positron emitting elements that allow new molecular tracers to be labeled. Micro-MRI has been improved in terms of spatial resolution and sensitivity by increased magnet field strength and development of special purpose coils and associated scan protocols. Of particular interest is the associated ability to image local mechanical function and solute transport processes which can be directly related to the molecular information. This is further strengthened by the synergistic integration of the PET with MRI. Micro-SPECT has been improved by use of coded aperture imaging approaches as well as image reconstruction algorithms which can better deal with the photon limited scan data. The limited spatial resolution can be partially overcome by integrating the SPECT with CT. Micro-CT by itself provides exquisite spatial resolution of anatomy, but recent developments of high spatial resolution photon counting and spectrally-sensitive imaging arrays, combined with x-ray optical devices, have promise for actual molecular identification by virtue of the chemical bond lengths of molecules, especially of bio-polymers. Conclusion With the increasing use of small animals for evaluating new clinical imaging techniques as well as providing increased insights into patho-physiological phenomena, the availability of improved detection systems, scanning protocols and associated software, the repertoire of molecular imaging is greatly increased in sensitivity and specificity. PMID:20457793

  20. Depth-time interpolation of feature trends extracted from mobile microelectrode data with kernel functions.

    PubMed

    Wong, Stephen; Hargreaves, Eric L; Baltuch, Gordon H; Jaggi, Jurg L; Danish, Shabbar F

    2012-01-01

    Microelectrode recording (MER) is necessary for precision localization of target structures such as the subthalamic nucleus during deep brain stimulation (DBS) surgery. Attempts to automate this process have produced quantitative temporal trends (feature activity vs. time) extracted from mobile MER data. Our goal was to evaluate computational methods of generating spatial profiles (feature activity vs. depth) from temporal trends that would decouple automated MER localization from the clinical procedure and enhance functional localization in DBS surgery. We evaluated two methods of interpolation (standard vs. kernel) that generated spatial profiles from temporal trends. We compared interpolated spatial profiles to true spatial profiles that were calculated with depth windows, using correlation coefficient analysis. Excellent approximation of true spatial profiles is achieved by interpolation. Kernel-interpolated spatial profiles produced superior correlation coefficient values at optimal kernel widths (r = 0.932-0.940) compared to standard interpolation (r = 0.891). The choice of kernel function and kernel width resulted in trade-offs in smoothing and resolution. Interpolation of feature activity to create spatial profiles from temporal trends is accurate and can standardize and facilitate MER functional localization of subcortical structures. The methods are computationally efficient, enhancing localization without imposing additional constraints on the MER clinical procedure during DBS surgery. Copyright © 2012 S. Karger AG, Basel.

  1. Advancing the quantification of humid tropical forest cover loss with multi-resolution optical remote sensing data: Sampling & wall-to-wall mapping

    NASA Astrophysics Data System (ADS)

    Broich, Mark

    Humid tropical forest cover loss is threatening the sustainability of ecosystem goods and services as vast forest areas are rapidly cleared for industrial scale agriculture and tree plantations. Despite the importance of humid tropical forest in the provision of ecosystem services and economic development opportunities, the spatial and temporal distribution of forest cover loss across large areas is not well quantified. Here I improve the quantification of humid tropical forest cover loss using two remote sensing-based methods: sampling and wall-to-wall mapping. In all of the presented studies, the integration of coarse spatial, high temporal resolution data with moderate spatial, low temporal resolution data enable advances in quantifying forest cover loss in the humid tropics. Imagery from the Moderate Resolution Imaging Spectroradiometer (MODIS) are used as the source of coarse spatial resolution, high temporal resolution data and imagery from the Landsat Enhanced Thematic Mapper Plus (ETM+) sensor are used as the source of moderate spatial, low temporal resolution data. In a first study, I compare the precision of different sampling designs for the Brazilian Amazon using the annual deforestation maps derived by the Brazilian Space Agency for reference. I show that sampling designs can provide reliable deforestation estimates; furthermore, sampling designs guided by MODIS data can provide more efficient estimates than the systematic design used for the United Nations Food and Agricultural Organization Forest Resource Assessment 2010. Sampling approaches, such as the one demonstrated, are viable in regions where data limitations, such as cloud contamination, limit exhaustive mapping methods. Cloud-contaminated regions experiencing high rates of change include Insular Southeast Asia, specifically Indonesia and Malaysia. Due to persistent cloud cover, forest cover loss in Indonesia has only been mapped at a 5-10 year interval using photo interpretation of single best Landsat images. Such an approach does not provide timely results, and cloud cover reduces the utility of map outputs. In a second study, I develop a method to exhaustively mine the recently opened Landsat archive for cloud-free observations and automatically map forest cover loss for Sumatra and Kalimantan for the 2000-2005 interval. In a comparison with a reference dataset consisting of 64 Landsat sample blocks, I show that my method, using per pixel time-series, provides more accurate forest cover loss maps for multiyear intervals than approaches using image composites. In a third study, I disaggregate Landsat-mapped forest cover loss, mapped over a multiyear interval, by year using annual forest cover loss maps generated from coarse spatial, high temporal resolution MODIS imagery. I further disaggregate and analyze forest cover loss by forest land use, and provinces. Forest cover loss trends show high spatial and temporal variability. These results underline the importance of annual mapping for the quantification of forest cover loss in Indonesia, specifically in the light of the developing Reducing Emissions from Deforestation and Forest Degradation in Developing Countries policy framework (REDD). All three studies highlight the advances in quantifying forest cover loss in the humid tropics made by integrating coarse spatial, high temporal resolution data with moderate spatial, low temporal resolution data. The three methods presented can be combined into an integrated monitoring strategy.

  2. Nanoantenna-Enhanced Infrared Spectroscopic Chemical Imaging.

    PubMed

    Kühner, Lucca; Hentschel, Mario; Zschieschang, Ute; Klauk, Hagen; Vogt, Jochen; Huck, Christian; Giessen, Harald; Neubrech, Frank

    2017-05-26

    Spectroscopic infrared chemical imaging is ideally suited for label-free and spatially resolved characterization of molecular species, but often suffers from low infrared absorption cross sections. Here, we overcome this limitation by utilizing confined electromagnetic near-fields of resonantly excited plasmonic nanoantennas, which enhance the molecular absorption by orders of magnitude. In the experiments, we evaporate microstructured chemical patterns of C 60 and pentacene with nanometer thickness on top of homogeneous arrays of tailored nanoantennas. Broadband mid-infrared spectra containing plasmonic and vibrational information were acquired with diffraction-limited resolution using a two-dimensional focal plane array detector. Evaluating the enhanced infrared absorption at the respective frequencies, spatially resolved chemical images were obtained. In these chemical images, the microstructured chemical patterns are only visible if nanoantennas are used. This confirms the superior performance of our approach over conventional spectroscopic infrared imaging. In addition to the improved sensitivity, our technique provides chemical selectivity, which would not be available with plasmonic imaging that is based on refractive index sensing. To extend the accessible spectral bandwidth of nanoantenna-enhanced spectroscopic imaging, we employed nanostructures with dual-band resonances, providing broadband plasmonic enhancement and sensitivity. Our results demonstrate the potential of nanoantenna-enhanced spectroscopic infrared chemical imaging for spatially resolved characterization of organic layers with thicknesses of several nanometers. This is of potential interest for medical applications which are currently hampered by state-of-art infrared techniques, e.g., for distinguishing cancerous from healthy tissues.

  3. High Resolution Ultrasound Superharmonic Perfusion Imaging: In Vivo Feasibility and Quantification of Dynamic Contrast-Enhanced Acoustic Angiography.

    PubMed

    Lindsey, Brooks D; Shelton, Sarah E; Martin, K Heath; Ozgun, Kathryn A; Rojas, Juan D; Foster, F Stuart; Dayton, Paul A

    2017-04-01

    Mapping blood perfusion quantitatively allows localization of abnormal physiology and can improve understanding of disease progression. Dynamic contrast-enhanced ultrasound is a low-cost, real-time technique for imaging perfusion dynamics with microbubble contrast agents. Previously, we have demonstrated another contrast agent-specific ultrasound imaging technique, acoustic angiography, which forms static anatomical images of the superharmonic signal produced by microbubbles. In this work, we seek to determine whether acoustic angiography can be utilized for high resolution perfusion imaging in vivo by examining the effect of acquisition rate on superharmonic imaging at low flow rates and demonstrating the feasibility of dynamic contrast-enhanced superharmonic perfusion imaging for the first time. Results in the chorioallantoic membrane model indicate that frame rate and frame averaging do not affect the measured diameter of individual vessels observed, but that frame rate does influence the detection of vessels near and below the resolution limit. The highest number of resolvable vessels was observed at an intermediate frame rate of 3 Hz using a mechanically-steered prototype transducer. We also demonstrate the feasibility of quantitatively mapping perfusion rate in 2D in a mouse model with spatial resolution of ~100 μm. This type of imaging could provide non-invasive, high resolution quantification of microvascular function at penetration depths of several centimeters.

  4. Detecting metastasis of gastric carcinoma using high-resolution micro-CT system: in vivo small animal study

    NASA Astrophysics Data System (ADS)

    Liu, Junting; Tian, Jie; Liang, Jimin; Li, Xiangsi; Yang, Xiang; Chen, Xiaofeng; Chen, Yi; Zhou, Yuanfang; Wang, Xiaorui

    2011-03-01

    Immunocytochemical and immunofluorescence staining are used for identifying the characteristics of metastasis in traditional ways. Micro-computed tomography (micro-CT) is a useful tool for monitoring and longitudinal imaging of tumor in small animal in vivo. In present study, we evaluated the feasibility of the detection for metastasis of gastric carcinoma by high-resolution micro-CT system with omnipaque accumulative enhancement method in the organs. Firstly, a high-resolution micro-CT ZKKS-MCT-sharp micro-CT was developed by our research group and Guangzhou Zhongke Kaisheng Medical Technology Co., Ltd. Secondly, several gastric carcinoma models were established through inoculating 2x106 BGC-823 gastric carcinoma cells subcutaneously. Thirdly, micro-CT scanning was performed after accumulative enhancement method of intraperitoneal injection of omnipaque contrast agent containing 360 mg iodine with a concentration of 350 mg I/ml. Finally, we obtained high-resolution anatomical information of the metastasis in vivo in a BALB/c NuNu nude mouse, the 3D tumor architecture is revealed in exquisite detail at about 35 μm spatial resolution. In addition, the accurate shape and volume of the micrometastasis as small as 0.78 mm3 can be calculated with our software. Overall, our data suggest that this imaging approach and system could be used to enhance the understanding of tumor proliferation, metastasis and could be the basis for evaluating anti-tumor therapies.

  5. Comparison of SeaWinds Backscatter Imaging Algorithms

    PubMed Central

    Long, David G.

    2017-01-01

    This paper compares the performance and tradeoffs of various backscatter imaging algorithms for the SeaWinds scatterometer when multiple passes over a target are available. Reconstruction methods are compared with conventional gridding algorithms. In particular, the performance and tradeoffs in conventional ‘drop in the bucket’ (DIB) gridding at the intrinsic sensor resolution are compared to high-spatial-resolution imaging algorithms such as fine-resolution DIB and the scatterometer image reconstruction (SIR) that generate enhanced-resolution backscatter images. Various options for each algorithm are explored, including considering both linear and dB computation. The effects of sampling density and reconstruction quality versus time are explored. Both simulated and actual data results are considered. The results demonstrate the effectiveness of high-resolution reconstruction using SIR as well as its limitations and the limitations of DIB and fDIB. PMID:28828143

  6. Remote Sensing of Vineyard FPAR, with Implications for Irrigation Scheduling

    NASA Technical Reports Server (NTRS)

    Johnson, Lee F.; Scholasch, Thibaut

    2004-01-01

    Normalized difference vegetation index (NDVI) data, acquired at two-meter resolution by an airborne ADAR System 5500, were compared with fraction of photosynthetically active radiation (FPAR) absorbed by commercial vineyards in Napa Valley, California. An empirical line correction was used to transform image digital counts to surface reflectance. "Apparent" NDVI (generated from digital counts) and "corrected" NDVI (from reflectance) were both strongly related to FPAR of range 0.14-0.50 (both r(sup 2) = 0.97, P < 0.01). By suppressing noise, corrected NDVI should form a more spatially and temporally stable relationship with FPAR, reducing the need for repeated field support. Study results suggest the possibility of using optical remote sensing to monitor the transpiration crop coefficient, thus providing an enhanced spatial resolution component to crop water budget calculations and irrigation management.

  7. Computational multispectral video imaging [Invited].

    PubMed

    Wang, Peng; Menon, Rajesh

    2018-01-01

    Multispectral imagers reveal information unperceivable to humans and conventional cameras. Here, we demonstrate a compact single-shot multispectral video-imaging camera by placing a micro-structured diffractive filter in close proximity to the image sensor. The diffractive filter converts spectral information to a spatial code on the sensor pixels. Following a calibration step, this code can be inverted via regularization-based linear algebra to compute the multispectral image. We experimentally demonstrated spectral resolution of 9.6 nm within the visible band (430-718 nm). We further show that the spatial resolution is enhanced by over 30% compared with the case without the diffractive filter. We also demonstrate Vis-IR imaging with the same sensor. Because no absorptive color filters are utilized, sensitivity is preserved as well. Finally, the diffractive filters can be easily manufactured using optical lithography and replication techniques.

  8. Reconstruction of a Three Hourly 1-km Land Surface Air Temperature Dataset in the Qinghai-Tibet Plateau

    NASA Astrophysics Data System (ADS)

    Zhou, J.; Ding, L.

    2017-12-01

    Land surface air temperature (SAT) is an important parameter in the modeling of radiation balance and energy budget of the earth surface. Generally, SAT is measured at ground meteorological stations; then SAT mapping is possible though a spatial interpolation process. The interpolated SAT map relies on the spatial distribution of ground stations, the terrain, and many other factors; thus, it has great uncertainties in regions with complicated terrain. Instead, SAT map can also be obtained through physical modeling of interactions between the land surface and the atmosphere. Such dataset generally has coarse spatial resolution (e.g. coarser than 0.1°) and cannot satisfy the applications at fine scales, e.g. 1 km. This presentation reports the reconstruction of a three hourly 1-km SAT dataset from 2001 to 2015 over the Qinghai-Tibet Plateau. The terrain in the Qinghai-Tibet Plateau, especially in the eastern part, is extremely complicated. Two SAT datasets with good qualities are used in this study. The first one is from the 3h China Meteorological Forcing Dataset with a 0.1° resolution released by the Institute of Tibetan Plateau Research, Chinese Academy of Sciences (Yang et al., 2010); the second one is from the ERA-Interim product with the same temporal resolution and a 0.125° resolution. A statistical approach is developed to downscale the spatial resolution of the derived SAT to 1-km. The elevation and the normalized difference vegetation index (NDVI) are selected as two scaling factors in the downscaling approach. Results demonstrate there is significantly negative correlation between the SAT and elevation in all seasons; there is also significantly negative correlation between the SAT and NDVI in the vegetation growth seasons, while the correlation decreases in the other seasons. Therefore, a temporally dynamic downscaling approach is feasible to enhance the spatial resolution of the SAT. Compared with the SAT at the 0.1° or 0.125°, the reconstructed 1-km SAT can provide much more spatial details in areas with complicated terrain. Additionally, the 1-km SAT agrees well with the ground measured air temperatures as well as the SAT before downscaling. The reconstructed SAT will be beneficial for the modeling of surface radiation balance and energy budget over the Qinghai-Tibet Plateau.

  9. Restoring the spatial resolution of refocus images on 4D light field

    NASA Astrophysics Data System (ADS)

    Lim, JaeGuyn; Park, ByungKwan; Kang, JooYoung; Lee, SeongDeok

    2010-01-01

    This paper presents the method for generating a refocus image with restored spatial resolution on a plenoptic camera, which functions controlling the depth of field after capturing one image unlike a traditional camera. It is generally known that the camera captures 4D light field (angular and spatial information of light) within a limited 2D sensor and results in reducing 2D spatial resolution due to inevitable 2D angular data. That's the reason why a refocus image is composed of a low spatial resolution compared with 2D sensor. However, it has recently been known that angular data contain sub-pixel spatial information such that the spatial resolution of 4D light field can be increased. We exploit the fact for improving the spatial resolution of a refocus image. We have experimentally scrutinized that the spatial information is different according to the depth of objects from a camera. So, from the selection of refocused regions (corresponding depth), we use corresponding pre-estimated sub-pixel spatial information for reconstructing spatial resolution of the regions. Meanwhile other regions maintain out-of-focus. Our experimental results show the effect of this proposed method compared to existing method.

  10. High Spatial Resolution Commercial Satellite Imaging Product Characterization

    NASA Technical Reports Server (NTRS)

    Ryan, Robert E.; Pagnutti, Mary; Blonski, Slawomir; Ross, Kenton W.; Stnaley, Thomas

    2005-01-01

    NASA Stennis Space Center's Remote Sensing group has been characterizing privately owned high spatial resolution multispectral imaging systems, such as IKONOS, QuickBird, and OrbView-3. Natural and man made targets were used for spatial resolution, radiometric, and geopositional characterizations. Higher spatial resolution also presents significant adjacency effects for accurate reliable radiometry.

  11. A Millimetre-Wave Cuboid Solid Immersion Lens with Intensity-Enhanced Amplitude Mask Apodization

    NASA Astrophysics Data System (ADS)

    Yue, Liyang; Yan, Bing; Monks, James N.; Dhama, Rakesh; Wang, Zengbo; Minin, Oleg V.; Minin, Igor V.

    2018-06-01

    Photonic jet is a narrow, highly intensive, weak-diverging beam propagating into a background medium and can be produced by a cuboid solid immersion lens (SIL) in both transmission and reflection modes. Amplitude mask apodization is an optical method to further improve the spatial resolution of a SIL imaging system via reduction of waist size of photonic jet, but always leading to intensity loss due to central masking of the incoming plane wave. In this letter, we report a particularly sized millimetre-wave cuboid SIL with the intensity-enhanced amplitude mask apodization for the first time. It is able to simultaneously deliver extra intensity enhancement and waist narrowing to the produced photonic jet. Both numerical simulation and experimental verification of the intensity-enhanced apodization effect are demonstrated using a copper-masked Teflon cuboid SIL with 22-mm side length under radiation of a plane wave with 8-mm wavelength. Peak intensity enhancement and the lateral resolution of the optical system increase by about 36.0% and 36.4% in this approach, respectively.

  12. Spectroscopic photon localization microscopy: breaking the resolution limit of single molecule localization microscopy (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Dong, Biqin; Almassalha, Luay Matthew; Urban, Ben E.; Nguyen, The-Quyen; Khuon, Satya; Chew, Teng-Leong; Backman, Vadim; Sun, Cheng; Zhang, Hao F.

    2017-02-01

    Distinguishing minute differences in spectroscopic signatures is crucial for revealing the fluorescence heterogeneity among fluorophores to achieve a high molecular specificity. Here we report spectroscopic photon localization microscopy (SPLM), a newly developed far-field spectroscopic imaging technique, to achieve nanoscopic resolution based on the principle of single-molecule localization microscopy while simultaneously uncovering the inherent molecular spectroscopic information associated with each stochastic event (Dong et al., Nature Communications 2016, in press). In SPLM, by using a slit-less monochromator, both the zero-order and the first-order diffractions from a grating were recorded simultaneously by an electron multiplying charge-coupled device to reveal the spatial distribution and the associated emission spectra of individual stochastic radiation events, respectively. As a result, the origins of photon emissions from different molecules can be identified according to their spectral differences with sub-nm spectral resolution, even when the molecules are within close proximity. With the newly developed algorithms including background subtraction and spectral overlap unmixing, we established and tested a method which can significantly extend the fundamental spatial resolution limit of single molecule localization microscopy by molecular discrimination through spectral regression. Taking advantage of this unique capability, we demonstrated improvement in spatial resolution of PALM/STORM up to ten fold with selected fluorophores. This technique can be readily adopted by other research groups to greatly enhance the optical resolution of single molecule localization microscopy without the need to modify their existing staining methods and protocols. This new resolving capability can potentially provide new insights into biological phenomena and enable significant research progress to be made in the life sciences.

  13. Tracking the ultrafast motion of a single molecule by femtosecond orbital imaging

    PubMed Central

    Yu, Ping; Repp, Jascha; Huber, Rupert

    2017-01-01

    Watching a single molecule move on its intrinsic time scale—one of the central goals of modern nanoscience—calls for measurements that combine ultrafast temporal resolution1–8 with atomic spatial resolution9–30. Steady-state experiments achieve the requisite spatial resolution, as illustrated by direct imaging of individual molecular orbitals using scanning tunnelling microscopy9–11 or the acquisition of tip-enhanced Raman and luminescence spectra with sub-molecular resolution27–29. But tracking the dynamics of a single molecule directly in the time domain faces the challenge that single-molecule excitations need to be confined to an ultrashort time window. A first step towards overcoming this challenge has combined scanning tunnelling microscopy with so-called ‘lightwave electronics”1–8, which uses the oscillating carrier wave of tailored light pulses to directly manipulate electronic motion on time scales faster even than that of a single cycle of light. Here we use such ultrafast terahertz scanning tunnelling microscopy to access a state-selective tunnelling regime, where the peak of a terahertz electric-field waveform transiently opens an otherwise forbidden tunnelling channel through a single molecular state and thereby removes a single electron from an individual pentacene molecule’s highest occupied molecular orbital within a time window shorter than one oscillation cycle of the terahertz wave. We exploit this effect to record ~100 fs snapshot images of the structure of the orbital involved, and to reveal through pump-probe measurements coherent molecular vibrations at terahertz frequencies directly in the time domain and with sub-angstrom spatial resolution. We anticipate that the combination of lightwave electronics1–8 and atomic resolution of our approach will open the door to controlling electronic motion inside individual molecules at optical clock rates. PMID:27830788

  14. Development of a Tip-Enhanced Near-Field Optical Microscope for Nanoscale Interrogation of Surface Chemistry and Plasmonic Phenomena

    NASA Astrophysics Data System (ADS)

    Heilman, Alexander Lee

    Optical microscopy and spectroscopy are invaluable tools for the physical and chemical characterization of materials and surfaces in a wide range of scientific disciplines. However, the application of conventional optical methods in the study of nanomaterials is inherently limited by diffraction. Tip-enhanced near-field optical microscopy (TENOM) is a hybrid technique that marries optical spectroscopy with scanning probe microscopy to overcome the spatial resolution limit imposed by diffraction. By coupling optical energy into the plasmonic modes of a sharp metal probe tip, a strong, localized optical field is generated near the tip's apex and is used to enhance spectroscopic emissions within a sub-diffraction-limited volume. In this thesis, we describe the design, construction, validation, and application of a custom TENOM instrument with a unique attenuated total reflectance (ATR)-geometry excitation/detection system. The specific goals of this work were: (i) to develop a versatile TENOM instrument capable of investigating a variety of optical phenomena at the nanoscale, (ii) to use the instrument to demonstrate chemical interrogation of surfaces with sub-diffraction-limited spatial resolution (i.e., at super resolution), (iii) to apply the instrument to study plasmonic phenomena that influence spectroscopic enhancement in TENOM measurements, and (iv) to leverage resulting insights to develop systematic improvements that expand the ultimate capabilities of near-field optical interrogation techniques. The TENOM instrument described herein is comprised of three main components: an atomic force microscope (AFM), a side-on confocal Raman microscope, and a novel ATR excitation/detection system. The design of each component is discussed along with the results of relevant validation experiments, which were performed to rigorously assess each component's performance. Finite-difference time-domain (FDTD) optical simulations were also developed and used extensively to evaluate the results of validation studies and to optimize experimental design and instrument performance. By combining and synchronizing the operation of the instrument's three components, we perform a variety of near-field optical experiments that demonstrate the instrument's functionality and versatility. ATR illumination is combined with a plasmonic AFM tip to show that: (i) the tip can quantitatively transduce the optical near-field (evanescent waves) above the surface by scattering photons into the far-field, (ii) the ATR geometry enables excitation and characterization of surface plasmon polaritons (SPPs), whose associated optical fields are shown to enhance Raman scattering from a thin layer of copper phthalocyanine (CuPc), and (iii) SPPs can be used to plasmonically excite the tip for super-resolution chemical imaging of patterned CuPc via tip-enhanced Raman spectroscopy (TERS). ATR-illumination TERS is quantitatively compared with side-on illumination. In both cases, spatial resolution was better than 40 nm and tip-on/tip-off Raman enhancement factors were >6500. Furthermore, ATR illumination was shown to provide similar Raman signal levels at lower "effective'' pump powers due to additional optical energy delivered by SPPs to the active region in the tip-surface gap. We also investigate the sensitivity of the TENOM instrument to changes in the plasmonic properties of the tip-surface system in the strongly-coupled regime at small tip-surface separations. Specifically, we demonstrate detection of a resonant plasmonic tip-surface mode (a gap plasmon) that dramatically influences the optical response of the system, and we use experimental results and FDTD simulations to support a hypothesized mechanism. Moreover, we confirm that the gap plasmon resonance has a strong effect on the enhancement of both fluorescence and Raman scattering, and we propose that this phenomenon could ultimately be exploited to improve sensitivity in super-resolution chemical imaging measurements. Finally, we recommend a straightforward modification to the TENOM instrument that could enable future application of these gap-mode plasmon resonances to increase spectroscopic enhancements by an order of magnitude.

  15. Factors affecting the performance of large-aperture microphone arrays.

    PubMed

    Silverman, Harvey F; Patterson, William R; Sachar, Joshua

    2002-05-01

    Large arrays of microphones have been proposed and studied as a possible means of acquiring data in offices, conference rooms, and auditoria without requiring close-talking microphones. When such an array essentially surrounds all possible sources, it is said to have a large aperture. Large-aperture arrays have attractive properties of spatial resolution and signal-to-noise enhancement. This paper presents a careful comparison of theoretical and measured performance for an array of 256 microphones using simple delay-and-sum beamforming. This is the largest currently functional, all digital-signal-processing array that we know of. The array is wall-mounted in the moderately adverse environment of a general-purpose laboratory (8 m x 8 m x 3 m). The room has a T60 reverberation time of 550 ms. Reverberation effects in this room severely impact the array's performance. However, the width of the main lobe remains comparable to that of a simplified prediction. Broadband spatial resolution shows a single central peak with 10 dB gain about 0.4 m in diameter at the -3 dB level. Away from that peak, the response is approximately flat over most of the room. Optimal weighting for signal-to-noise enhancement degrades the spatial resolution minimally. Experimentally, we verify that signal-to-noise gain is less than proportional to the square root of the number of microphones probably due to the partial correlation of the noise between channels, to variation of signal intensity with polar angle about the source, and to imperfect correlation of the signal over the array caused by reverberations. We show measurements of the relative importance of each effect in our environment.

  16. Factors affecting the performance of large-aperture microphone arrays

    NASA Astrophysics Data System (ADS)

    Silverman, Harvey F.; Patterson, William R.; Sachar, Joshua

    2002-05-01

    Large arrays of microphones have been proposed and studied as a possible means of acquiring data in offices, conference rooms, and auditoria without requiring close-talking microphones. When such an array essentially surrounds all possible sources, it is said to have a large aperture. Large-aperture arrays have attractive properties of spatial resolution and signal-to-noise enhancement. This paper presents a careful comparison of theoretical and measured performance for an array of 256 microphones using simple delay-and-sum beamforming. This is the largest currently functional, all digital-signal-processing array that we know of. The array is wall-mounted in the moderately adverse environment of a general-purpose laboratory (8 m×8 m×3 m). The room has a T60 reverberation time of 550 ms. Reverberation effects in this room severely impact the array's performance. However, the width of the main lobe remains comparable to that of a simplified prediction. Broadband spatial resolution shows a single central peak with 10 dB gain about 0.4 m in diameter at the -3 dB level. Away from that peak, the response is approximately flat over most of the room. Optimal weighting for signal-to-noise enhancement degrades the spatial resolution minimally. Experimentally, we verify that signal-to-noise gain is less than proportional to the square root of the number of microphones probably due to the partial correlation of the noise between channels, to variation of signal intensity with polar angle about the source, and to imperfect correlation of the signal over the array caused by reverberations. We show measurements of the relative importance of each effect in our environment.

  17. Automated Verification of Spatial Resolution in Remotely Sensed Imagery

    NASA Technical Reports Server (NTRS)

    Davis, Bruce; Ryan, Robert; Holekamp, Kara; Vaughn, Ronald

    2011-01-01

    Image spatial resolution characteristics can vary widely among sources. In the case of aerial-based imaging systems, the image spatial resolution characteristics can even vary between acquisitions. In these systems, aircraft altitude, speed, and sensor look angle all affect image spatial resolution. Image spatial resolution needs to be verified with estimators that include the ground sample distance (GSD), the modulation transfer function (MTF), and the relative edge response (RER), all of which are key components of image quality, along with signal-to-noise ratio (SNR) and dynamic range. Knowledge of spatial resolution parameters is important to determine if features of interest are distinguishable in imagery or associated products, and to develop image restoration algorithms. An automated Spatial Resolution Verification Tool (SRVT) was developed to rapidly determine the spatial resolution characteristics of remotely sensed aerial and satellite imagery. Most current methods for assessing spatial resolution characteristics of imagery rely on pre-deployed engineered targets and are performed only at selected times within preselected scenes. The SRVT addresses these insufficiencies by finding uniform, high-contrast edges from urban scenes and then using these edges to determine standard estimators of spatial resolution, such as the MTF and the RER. The SRVT was developed using the MATLAB programming language and environment. This automated software algorithm assesses every image in an acquired data set, using edges found within each image, and in many cases eliminating the need for dedicated edge targets. The SRVT automatically identifies high-contrast, uniform edges and calculates the MTF and RER of each image, and when possible, within sections of an image, so that the variation of spatial resolution characteristics across the image can be analyzed. The automated algorithm is capable of quickly verifying the spatial resolution quality of all images within a data set, enabling the appropriate use of those images in a number of applications.

  18. Real-Time Nanoscopy by Using Blinking Enhanced Quantum Dots

    PubMed Central

    Watanabe, Tomonobu M.; Fukui, Shingo; Jin, Takashi; Fujii, Fumihiko; Yanagida, Toshio

    2010-01-01

    Superresolution optical microscopy (nanoscopy) is of current interest in many biological fields. Superresolution optical fluctuation imaging, which utilizes higher-order cumulant of fluorescence temporal fluctuations, is an excellent method for nanoscopy, as it requires neither complicated optics nor illuminations. However, it does need an impractical number of images for real-time observation. Here, we achieved real-time nanoscopy by modifying superresolution optical fluctuation imaging and enhancing the fluctuation of quantum dots. Our developed quantum dots have higher blinking than commercially available ones. The fluctuation of the blinking improved the resolution when using a variance calculation for each pixel instead of a cumulant calculation. This enabled us to obtain microscopic images with 90-nm and 80-ms spatial-temporal resolution by using a conventional fluorescence microscope without any optics or devices. PMID:20923631

  19. Temporal focusing microscopy combined with three-dimensional structured illumination

    NASA Astrophysics Data System (ADS)

    Isobe, Keisuke; Toda, Keisuke; Song, Qiyuan; Kannari, Fumihiko; Kawano, Hiroyuki; Miyawaki, Atsushi; Midorikawa, Katsumi

    2017-05-01

    Temporal focusing microscopy provides the optical sectioning capability in wide-field two-photon fluorescence imaging. Here, we demonstrate temporal focusing microscopy combined with three-dimensional structured illumination, which enables us to enhance the three-dimensional spatial resolution and reject the background fluorescence. Experimentally, the periodic pattern of the illumination was produced not only in the lateral direction but also in the axial direction by the interference between three temporal focusing pulses, which were easily generated using a digital micromirror device. The lateral resolution and optical sectioning capability were successfully enhanced by factors of 1.6 and 3.6, respectively, compared with those of temporal focusing microscopy. In the two-photon fluorescence imaging of a tissue-like phantom, the out-of-focus background fluorescence and the scattered background fluorescence could also be rejected.

  20. Earth Observing System (EOS) Moderate Resolution Imaging Spectroradiometer (MODIS) Global Snow-Cover Maps

    NASA Technical Reports Server (NTRS)

    Hall, Dorothy K.; Riggs, George A.; Salomonson, Vincent V.; Scharfen, Greg R.

    2000-01-01

    Following the 1999 launch of the Earth Observing System (EOS) Moderate Resolution Imaging Spectroradiometer (MODIS), the capability exists to produce global snow-cover maps on a daily basis at 500-m resolution. Eight-day composite snow-cover maps will also be available. MODIS snow-cover products are produced at Goddard Space Flight Center and archived and distributed by the National Snow and Ice Data Center (NSIDC) in Boulder, Colorado. The products are available in both orbital and gridded formats. An online search and order tool and user-services staff will be available at NSIDC to assist users with the snow products. The snow maps are available at a spatial resolution of 500 m, and 1/4 degree x 1/4 degree spatial resolution, and provide information on sub-pixel (fractional) snow cover. Pre-launch validation work has shown that the MODIS snow-mapping algorithms perform best under conditions of continuous snow cover in low vegetation areas, but can also map snow cover in dense forests. Post-launch validation activities will be performed using field and aircraft measurements from a February 2000 validation mission, as well as from existing satellite-derived snow-cover maps from NOAA and Landsat-7 Enhanced Thematic Mapper Plus (ETM+).

  1. Thematic and spatial resolutions affect model-based predictions of tree species distribution.

    PubMed

    Liang, Yu; He, Hong S; Fraser, Jacob S; Wu, ZhiWei

    2013-01-01

    Subjective decisions of thematic and spatial resolutions in characterizing environmental heterogeneity may affect the characterizations of spatial pattern and the simulation of occurrence and rate of ecological processes, and in turn, model-based tree species distribution. Thus, this study quantified the importance of thematic and spatial resolutions, and their interaction in predictions of tree species distribution (quantified by species abundance). We investigated how model-predicted species abundances changed and whether tree species with different ecological traits (e.g., seed dispersal distance, competitive capacity) had different responses to varying thematic and spatial resolutions. We used the LANDIS forest landscape model to predict tree species distribution at the landscape scale and designed a series of scenarios with different thematic (different numbers of land types) and spatial resolutions combinations, and then statistically examined the differences of species abundance among these scenarios. Results showed that both thematic and spatial resolutions affected model-based predictions of species distribution, but thematic resolution had a greater effect. Species ecological traits affected the predictions. For species with moderate dispersal distance and relatively abundant seed sources, predicted abundance increased as thematic resolution increased. However, for species with long seeding distance or high shade tolerance, thematic resolution had an inverse effect on predicted abundance. When seed sources and dispersal distance were not limiting, the predicted species abundance increased with spatial resolution and vice versa. Results from this study may provide insights into the choice of thematic and spatial resolutions for model-based predictions of tree species distribution.

  2. Thematic and Spatial Resolutions Affect Model-Based Predictions of Tree Species Distribution

    PubMed Central

    Liang, Yu; He, Hong S.; Fraser, Jacob S.; Wu, ZhiWei

    2013-01-01

    Subjective decisions of thematic and spatial resolutions in characterizing environmental heterogeneity may affect the characterizations of spatial pattern and the simulation of occurrence and rate of ecological processes, and in turn, model-based tree species distribution. Thus, this study quantified the importance of thematic and spatial resolutions, and their interaction in predictions of tree species distribution (quantified by species abundance). We investigated how model-predicted species abundances changed and whether tree species with different ecological traits (e.g., seed dispersal distance, competitive capacity) had different responses to varying thematic and spatial resolutions. We used the LANDIS forest landscape model to predict tree species distribution at the landscape scale and designed a series of scenarios with different thematic (different numbers of land types) and spatial resolutions combinations, and then statistically examined the differences of species abundance among these scenarios. Results showed that both thematic and spatial resolutions affected model-based predictions of species distribution, but thematic resolution had a greater effect. Species ecological traits affected the predictions. For species with moderate dispersal distance and relatively abundant seed sources, predicted abundance increased as thematic resolution increased. However, for species with long seeding distance or high shade tolerance, thematic resolution had an inverse effect on predicted abundance. When seed sources and dispersal distance were not limiting, the predicted species abundance increased with spatial resolution and vice versa. Results from this study may provide insights into the choice of thematic and spatial resolutions for model-based predictions of tree species distribution. PMID:23861828

  3. Visual sensitivity and spatial resolution of the planktivorous fish, Atherinomorus forskalii (Atherinidae; Rüppell, 1838), to a polarized grating.

    PubMed

    Lerner, Amit; Shmulevitz, Ron; Browman, Howard I; Shashar, Nadav

    2017-02-01

    Polarized light detection has been documented in only a small number of fish species. The benefit of polarization vision for fish is not fully understood, nor is the transduction mechanism that underlies it. Past studies proposed that one possible advantage of polarization vision is that it enhances the contrast of zooplankton targets by breaking their transparency. Here, we used an optomotor apparatus to test the responses of the planktivorous Hardyhead silverside fish Atherinomorus forskalii (Atherinidae) to vertical unpolarized (intensity) and polarized gratings. We also tested and compared the spatial and temporal resolutions of A. forskalii in the intensity and polarization domains. A. forskalii responded to the polarization pattern, but only under illumination that included ultraviolet-blue (λ>380nm) wavelengths. The spatial resolution of A. forskalii was measured as a minimum separable angle of 0.57° (a 1-mm prey viewed from 100-mm distance). The temporal resolution to unpolarized vs. polarized gratings was constant, at 33 and 10Hz respectively at most of the stripe widths tested. At the smallest stripe width tested (1mm=the minimal separable angle), which correlates with the size of prey typically consumed by these fish, the temporal resolution to the polarized grating increased to 42Hz. We conclude that A. forskalii is polarization sensitive, may use polarization vision to improve detection of its planktonic prey, and that polarization may be perceived by the fish via a separate visual pathway than intensity. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Towards a New Assessment of Urban Areas from Local to Global Scales

    NASA Astrophysics Data System (ADS)

    Bhaduri, B. L.; Roy Chowdhury, P. K.; McKee, J.; Weaver, J.; Bright, E.; Weber, E.

    2015-12-01

    Since early 2000s, starting with NASA MODIS, satellite based remote sensing has facilitated collection of imagery with medium spatial resolution but high temporal resolution (daily). This trend continues with an increasing number of sensors and data products. Increasing spatial and temporal resolutions of remotely sensed data archives, from both public and commercial sources, have significantly enhanced the quality of mapping and change data products. However, even with automation of such analysis on evolving computing platforms, rates of data processing have been suboptimal largely because of the ever-increasing pixel to processor ratio coupled with limitations of the computing architectures. Novel approaches utilizing spatiotemporal data mining techniques and computational architectures have emerged that demonstrates the potential for sustained and geographically scalable landscape monitoring to be operational. We exemplify this challenge with two broad research initiatives on High Performance Geocomputation at Oak Ridge National Laboratory: (a) mapping global settlement distribution; (b) developing national critical infrastructure databases. Our present effort, on large GPU based architectures, to exploit high resolution (1m or less) satellite and airborne imagery for extracting settlements at global scale is yielding understanding of human settlement patterns and urban areas at unprecedented resolution. Comparison of such urban land cover database, with existing national and global land cover products, at various geographic scales in selected parts of the world is revealing intriguing patterns and insights for urban assessment. Early results, from the USA, Taiwan, and Egypt, indicate closer agreements (5-10%) in urban area assessments among databases at larger, aggregated geographic extents. However, spatial variability at local scales could be significantly different (over 50% disagreement).

  5. Integrated satellite data fusion and mining for monitoring lake water quality status of the Albufera de Valencia in Spain.

    PubMed

    Doña, Carolina; Chang, Ni-Bin; Caselles, Vicente; Sánchez, Juan M; Camacho, Antonio; Delegido, Jesús; Vannah, Benjamin W

    2015-03-15

    Lake eutrophication is a critical issue in the interplay of water supply, environmental management, and ecosystem conservation. Integrated sensing, monitoring, and modeling for a holistic lake water quality assessment with respect to multiple constituents is in acute need. The aim of this paper is to develop an integrated algorithm for data fusion and mining of satellite remote sensing images to generate daily estimates of some water quality parameters of interest, such as chlorophyll a concentrations and water transparency, to be applied for the assessment of the hypertrophic Albufera de Valencia. The Albufera de Valencia is the largest freshwater lake in Spain, which can often present values of chlorophyll a concentration over 200 mg m(-3) and values of transparency (Secchi Disk, SD) as low as 20 cm. Remote sensing data from Moderate Resolution Imaging Spectroradiometer (MODIS) and Landsat Thematic Mapper (TM) and Enhance Thematic Mapper (ETM+) images were fused to carry out an integrative near-real time water quality assessment on a daily basis. Landsat images are useful to study the spatial variability of the water quality parameters, due to its spatial resolution of 30 m, in comparison to the low spatial resolution (250/500 m) of MODIS. While Landsat offers a high spatial resolution, the low temporal resolution of 16 days is a significant drawback to achieve a near real-time monitoring system. This gap may be bridged by using MODIS images that have a high temporal resolution of 1 day, in spite of its low spatial resolution. Synthetic Landsat images were fused for dates with no Landsat overpass over the study area. Finally, with a suite of ground truth data, a few genetic programming (GP) models were derived to estimate the water quality using the fused surface reflectance data as inputs. The GP model for chlorophyll a estimation yielded a R(2) of 0.94, with a Root Mean Square Error (RMSE) = 8 mg m(-3), and the GP model for water transparency estimation using Secchi disk showed a R(2) of 0.89, with an RMSE = 4 cm. With this effort, the spatiotemporal variations of water transparency and chlorophyll a concentrations may be assessed simultaneously on a daily basis throughout the lake for environmental management. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Overlapped Fourier coding for optical aberration removal

    PubMed Central

    Horstmeyer, Roarke; Ou, Xiaoze; Chung, Jaebum; Zheng, Guoan; Yang, Changhuei

    2014-01-01

    We present an imaging procedure that simultaneously optimizes a camera’s resolution and retrieves a sample’s phase over a sequence of snapshots. The technique, termed overlapped Fourier coding (OFC), first digitally pans a small aperture across a camera’s pupil plane with a spatial light modulator. At each aperture location, a unique image is acquired. The OFC algorithm then fuses these low-resolution images into a full-resolution estimate of the complex optical field incident upon the detector. Simultaneously, the algorithm utilizes redundancies within the acquired dataset to computationally estimate and remove unknown optical aberrations and system misalignments via simulated annealing. The result is an imaging system that can computationally overcome its optical imperfections to offer enhanced resolution, at the expense of taking multiple snapshots over time. PMID:25321982

  7. Constructing a WISE High Resolution Galaxy Atlas

    NASA Technical Reports Server (NTRS)

    Jarrett, T. H.; Masci, F.; Tsai, C. W.; Petty, S.; Cluver, M.; Assef, Roberto J.; Benford, D.; Blain, A.; Bridge, C.; Donoso, E.; hide

    2012-01-01

    After eight months of continuous observations, the Wide-field Infrared Survey Explorer (WISE) mapped the entire sky at 3.4 micron, 4.6 micron, 12 micron, and 22 micron. We have begun a dedicated WISE High Resolution Galaxy Atlas project to fully characterize large, nearby galaxies and produce a legacy image atlas and source catalog. Here we summarize the deconvolution techniques used to significantly improve the spatial resolution of WISE imaging, specifically designed to study the internal anatomy of nearby galaxies. As a case study, we present results for the galaxy NGC 1566, comparing the WISE enhanced-resolution image processing to that of Spitzer, Galaxy Evolution Explorer, and ground-based imaging. This is the first paper in a two-part series; results for a larger sample of nearby galaxies are presented in the second paper.

  8. Integrated GNSS Attitude Determination and Positioning for Direct Geo-Referencing

    PubMed Central

    Nadarajah, Nandakumaran; Paffenholz, Jens-André; Teunissen, Peter J. G.

    2014-01-01

    Direct geo-referencing is an efficient methodology for the fast acquisition of 3D spatial data. It requires the fusion of spatial data acquisition sensors with navigation sensors, such as Global Navigation Satellite System (GNSS) receivers. In this contribution, we consider an integrated GNSS navigation system to provide estimates of the position and attitude (orientation) of a 3D laser scanner. The proposed multi-sensor system (MSS) consists of multiple GNSS antennas rigidly mounted on the frame of a rotating laser scanner and a reference GNSS station with known coordinates. Precise GNSS navigation requires the resolution of the carrier phase ambiguities. The proposed method uses the multivariate constrained integer least-squares (MC-LAMBDA) method for the estimation of rotating frame ambiguities and attitude angles. MC-LAMBDA makes use of the known antenna geometry to strengthen the underlying attitude model and, hence, to enhance the reliability of rotating frame ambiguity resolution and attitude determination. The reliable estimation of rotating frame ambiguities is consequently utilized to enhance the relative positioning of the rotating frame with respect to the reference station. This integrated (array-aided) method improves ambiguity resolution, as well as positioning accuracy between the rotating frame and the reference station. Numerical analyses of GNSS data from a real-data campaign confirm the improved performance of the proposed method over the existing method. In particular, the integrated method yields reliable ambiguity resolution and reduces position standard deviation by a factor of about 0.8, matching the theoretical gain of 3/4 for two antennas on the rotating frame and a single antenna at the reference station. PMID:25036330

  9. Compact full-motion video hyperspectral cameras: development, image processing, and applications

    NASA Astrophysics Data System (ADS)

    Kanaev, A. V.

    2015-10-01

    Emergence of spectral pixel-level color filters has enabled development of hyper-spectral Full Motion Video (FMV) sensors operating in visible (EO) and infrared (IR) wavelengths. The new class of hyper-spectral cameras opens broad possibilities of its utilization for military and industry purposes. Indeed, such cameras are able to classify materials as well as detect and track spectral signatures continuously in real time while simultaneously providing an operator the benefit of enhanced-discrimination-color video. Supporting these extensive capabilities requires significant computational processing of the collected spectral data. In general, two processing streams are envisioned for mosaic array cameras. The first is spectral computation that provides essential spectral content analysis e.g. detection or classification. The second is presentation of the video to an operator that can offer the best display of the content depending on the performed task e.g. providing spatial resolution enhancement or color coding of the spectral analysis. These processing streams can be executed in parallel or they can utilize each other's results. The spectral analysis algorithms have been developed extensively, however demosaicking of more than three equally-sampled spectral bands has been explored scarcely. We present unique approach to demosaicking based on multi-band super-resolution and show the trade-off between spatial resolution and spectral content. Using imagery collected with developed 9-band SWIR camera we demonstrate several of its concepts of operation including detection and tracking. We also compare the demosaicking results to the results of multi-frame super-resolution as well as to the combined multi-frame and multiband processing.

  10. Integrated GNSS attitude determination and positioning for direct geo-referencing.

    PubMed

    Nadarajah, Nandakumaran; Paffenholz, Jens-André; Teunissen, Peter J G

    2014-07-17

    Direct geo-referencing is an efficient methodology for the fast acquisition of 3D spatial data. It requires the fusion of spatial data acquisition sensors with navigation sensors, such as Global Navigation Satellite System (GNSS) receivers. In this contribution, we consider an integrated GNSS navigation system to provide estimates of the position and attitude (orientation) of a 3D laser scanner. The proposed multi-sensor system (MSS) consists of multiple GNSS antennas rigidly mounted on the frame of a rotating laser scanner and a reference GNSS station with known coordinates. Precise GNSS navigation requires the resolution of the carrier phase ambiguities. The proposed method uses the multivariate constrained integer least-squares (MC-LAMBDA) method for the estimation of rotating frame ambiguities and attitude angles. MC-LAMBDA makes use of the known antenna geometry to strengthen the underlying attitude model and, hence, to enhance the reliability of rotating frame ambiguity resolution and attitude determination. The reliable estimation of rotating frame ambiguities is consequently utilized to enhance the relative positioning of the rotating frame with respect to the reference station. This integrated (array-aided) method improves ambiguity resolution, as well as positioning accuracy between the rotating frame and the reference station. Numerical analyses of GNSS data from a real-data campaign confirm the improved performance of the proposed method over the existing method. In particular, the integrated method yields reliable ambiguity resolution and reduces position standard deviation by a factor of about 0:8, matching the theoretical gain of √ 3/4 for two antennas on the rotating frame and a single antenna at the reference station.

  11. A methodology for luminance map retrieval using airborne hyperspectral and photogrammetric data

    NASA Astrophysics Data System (ADS)

    Pipia, Luca; Alamús, Ramon; Tardà, Anna; Pérez, Fernando; Palà, Vicenç; Corbera, Jordi

    2014-10-01

    This paper puts forward a methodology developed at the Institut Cartogràfic i Geològic de Catalunya (ICGC) to quantify upwelling light flux using hyperspectral and photogrammetric airborne data. The work was carried out in the frame of a demonstrative study requested by the municipality of Sant Cugat del Vallès, in the vicinity of Barcelona (Spain), and aimed to envisage a new approach to assess artificial lighting policies and actions as alternative to field campaigns. Hyperspectral and high resolution multispectral/panchromatic data were acquired simultaneously over urban areas. In order to avoid moon light contributions, data were acquired during the first days of new moon phase. Hyperspectral data were radiometrically calibrated. Then, National Center for Environmental Prediction (NCEP) atmospheric profiles were employed to estimate the actual Column Water Vapor (CWV) to be passed to ModTran5.0 for the atmospheric transmissivity τ calculation. At-the-ground radiance was finally integrated using the photopic sensitivity curve to generate a luminance map (cdm-2) of the flown area by mosaicking the different flight tracks. In an attempt to improve the spatial resolution and enhance the dynamic range of the luminance map, a sensor-fusion strategy was finally looked into. DMC Photogrammetric data acquired simultaneously to hyperspectral information were converted into at-the-ground radiance and upscaled to CASI spatial resolution. High-resolution (HR) luminance maps with enhanced dynamic range were finally generated by linearly fitting up-scaled DMC mosaics to the CASI-based luminance information. In the end, a preliminary assessment of the methodology is carried out using non-simultaneous in-situ measurements.

  12. Remote sensing, geographical information systems, and spatial modeling for analyzing public transit services

    NASA Astrophysics Data System (ADS)

    Wu, Changshan

    Public transit service is a promising transportation mode because of its potential to address urban sustainability. Current ridership of public transit, however, is very low in most urban regions, particularly those in the United States. This woeful transit ridership can be attributed to many factors, among which poor service quality is key. Given this, there is a need for transit planning and analysis to improve service quality. Traditionally, spatially aggregate data are utilized in transit analysis and planning. Examples include data associated with the census, zip codes, states, etc. Few studies, however, address the influences of spatially aggregate data on transit planning results. In this research, previous studies in transit planning that use spatially aggregate data are reviewed. Next, problems associated with the utilization of aggregate data, the so-called modifiable areal unit problem (MAUP), are detailed and the need for fine resolution data to support public transit planning is argued. Fine resolution data is generated using intelligent interpolation techniques with the help of remote sensing imagery. In particular, impervious surface fraction, an important socio-economic indicator, is estimated through a fully constrained linear spectral mixture model using Landsat Enhanced Thematic Mapper Plus (ETM+) data within the metropolitan area of Columbus, Ohio in the United States. Four endmembers, low albedo, high albedo, vegetation, and soil are selected to model heterogeneous urban land cover. Impervious surface fraction is estimated by analyzing low and high albedo endmembers. With the derived impervious surface fraction, three spatial interpolation methods, spatial regression, dasymetric mapping, and cokriging, are developed to interpolate detailed population density. Results suggest that cokriging applied to impervious surface is a better alternative for estimating fine resolution population density. With the derived fine resolution data, a multiple route maximal covering/shortest path (MRMCSP) model is proposed to address the tradeoff between public transit service quality and access coverage in an established bus-based transit system. Results show that it is possible to improve current transit service quality by eliminating redundant or underutilized service stops. This research illustrates that fine resolution data can be efficiently generated to support urban planning, management and analysis. Further, this detailed data may necessitate the development of new spatial optimization models for use in analysis.

  13. Genome-wide profiling of chromosome interactions in Plasmodium falciparum characterizes nuclear architecture and reconfigurations associated with antigenic variation

    PubMed Central

    Lemieux, Jacob E; Kyes, Sue A; Otto, Thomas D; Feller, Avi I; Eastman, Richard T; Pinches, Robert A; Berriman, Matthew; Su, Xin-zhuan; Newbold, Chris I

    2013-01-01

    Spatial relationships within the eukaryotic nucleus are essential for proper nuclear function. In Plasmodium falciparum, the repositioning of chromosomes has been implicated in the regulation of the expression of genes responsible for antigenic variation, and the formation of a single, peri-nuclear nucleolus results in the clustering of rDNA. Nevertheless, the precise spatial relationships between chromosomes remain poorly understood, because, until recently, techniques with sufficient resolution have been lacking. Here we have used chromosome conformation capture and second-generation sequencing to study changes in chromosome folding and spatial positioning that occur during switches in var gene expression. We have generated maps of chromosomal spatial affinities within the P. falciparum nucleus at 25 Kb resolution, revealing a structured nucleolus, an absence of chromosome territories, and confirming previously identified clustering of heterochromatin foci. We show that switches in var gene expression do not appear to involve interaction with a distant enhancer, but do result in local changes at the active locus. These maps reveal the folding properties of malaria chromosomes, validate known physical associations, and characterize the global landscape of spatial interactions. Collectively, our data provide critical information for a better understanding of gene expression regulation and antigenic variation in malaria parasites. PMID:23980881

  14. Development and calibration of a new gamma camera detector using large square Photomultiplier Tubes

    NASA Astrophysics Data System (ADS)

    Zeraatkar, N.; Sajedi, S.; Teimourian Fard, B.; Kaviani, S.; Akbarzadeh, A.; Farahani, M. H.; Sarkar, S.; Ay, M. R.

    2017-09-01

    Large area scintillation detectors applied in gamma cameras as well as Single Photon Computed Tomography (SPECT) systems, have a major role in in-vivo functional imaging. Most of the gamma detectors utilize hexagonal arrangement of Photomultiplier Tubes (PMTs). In this work we applied large square-shaped PMTs with row/column arrangement and positioning. The Use of large square PMTs reduces dead zones in the detector surface. However, the conventional center of gravity method for positioning may not introduce an acceptable result. Hence, the digital correlated signal enhancement (CSE) algorithm was optimized to obtain better linearity and spatial resolution in the developed detector. The performance of the developed detector was evaluated based on NEMA-NU1-2007 standard. The acquired images using this method showed acceptable uniformity and linearity comparing to three commercial gamma cameras. Also the intrinsic and extrinsic spatial resolutions with low-energy high-resolution (LEHR) collimator at 10 cm from surface of the detector were 3.7 mm and 7.5 mm, respectively. The energy resolution of the camera was measured 9.5%. The performance evaluation demonstrated that the developed detector maintains image quality with a reduced number of used PMTs relative to the detection area.

  15. Retrieved Products from Simulated Hyperspectral Observations of a Hurricane

    NASA Technical Reports Server (NTRS)

    Susskind, Joel; Kouvaris, Louis; Iredell, Lena; Blaisdell, John

    2015-01-01

    Demonstrate via Observing System Simulation Experiments (OSSEs) the potential utility of flying high spatial resolution AIRS class IR sounders on future LEO and GEO missions.The study simulates and analyzes radiances for 3 sounders with AIRS spectral and radiometric properties on different orbits with different spatial resolutions: 1) Control run 13 kilometers AIRS spatial resolution at nadir on LEO in Aqua orbit; 2) 2 kilometer spatial resolution LEO sounder at nadir ARIES; 3) 5 kilometers spatial resolution sounder on a GEO orbit, radiances simulated every 72 minutes.

  16. Measurements and simulation of forest leaf area index and net primary productivity in Northern China.

    PubMed

    Wang, P; Sun, R; Hu, J; Zhu, Q; Zhou, Y; Li, L; Chen, J M

    2007-11-01

    Large scale process-based modeling is a useful approach to estimate distributions of global net primary productivity (NPP). In this paper, in order to validate an existing NPP model with observed data at site level, field experiments were conducted at three sites in northern China. One site is located in Qilian Mountain in Gansu Province, and the other two sites are in Changbaishan Natural Reserve and Dunhua County in Jilin Province. Detailed field experiments are discussed and field data are used to validate the simulated NPP. Remotely sensed images including Landsat Enhanced Thematic Mapper plus (ETM+, 30 m spatial resolution in visible and near infrared bands) and Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER, 15m spatial resolution in visible and near infrared bands) are used to derive maps of land cover, leaf area index, and biomass. Based on these maps, field measured data, soil texture and daily meteorological data, NPP of these sites are simulated for year 2001 with the boreal ecosystem productivity simulator (BEPS). The NPP in these sites ranges from 80 to 800 gCm(-2)a(-1). The observed NPP agrees well with the modeled NPP. This study suggests that BEPS can be used to estimate NPP in northern China if remotely sensed images of high spatial resolution are available.

  17. High-Resolution Forest Carbon Monitoring and Modeling: Continued Prototype Development and Deployment Across The Tri-state Area (MD, PA, DE), USA

    NASA Astrophysics Data System (ADS)

    Hurtt, G. C.; Birdsey, R.; Campbell, E.; Dolan, K. A.; Dubayah, R.; Escobar, V. M.; Finley, A. O.; Flanagan, S.; Huang, W.; Johnson, K.; Lister, A.; ONeil-Dunne, J.; Sepulveda Carlo, E.; Zhao, M.

    2017-12-01

    Local, national and international programs have increasing need for precise and accurate estimates of forest carbon and structure to support greenhouse gas reduction plans, climate initiatives, and other international climate treaty frameworks. In 2010 Congress directed NASA to initiate research towards the development of Carbon Monitoring Systems (CMS). In response, our team has worked to develop a robust, replicable framework to produce maps of high-resolution carbon stocks and future carbon sequestration potential. High-resolution (30m) maps of carbon stocks and uncertainty were produced by linking national 1m-resolution imagery and existing wall-to-wall airborne lidar to spatially explicit in-situ field observations such as the USFS Forest Inventory and Analysis (FIA) network. These same data, characterizing forest extent and vertical structure, were used to drive a prognostic ecosystem model to predict carbon fluxes and carbon sequestration potential at unprecedented spatial resolution and scale (90m), more than 100,000 times the spatial resolution of standard global models. Through project development, the domain of this research has expanded from two counties in MD (2,181 km2), to the entire state (32,133 km2), to the tri-state region of MD, PA, and DE (157,868 km2), covering forests in four major USDA ecological providences (Eastern Broadleaf, Northeastern Mixed, Outer Coastal Plain, and Central Appalachian). Across the region, we estimate 694 Tg C (14 DE, 113 MD, 567 PA) in above ground biomass, and estimate a carbon sequestration potential more than twice that amount. Empirical biomass products enhance existing approaches though high resolution accounting for trees outside traditional forest maps. Modeling products move beyond traditional MRV, and map future afforestation and reforestation potential for carbon at local actionable spatial scales. These products are relevant to multiple stakeholder needs in the region as discussed through the Tri-sate Working Group, and are actively being used to inform the state of MD's Greenhouse Gas Reduction Act. The approach is scalable, and provides a protoype framework for application in other domains and for future spaceborne lidar missions.

  18. Downscaling of land surface temperatures from SEVIRI

    NASA Astrophysics Data System (ADS)

    Bechtel, B.; Zaksek, K.

    2013-12-01

    Land surface temperature (LST) determines the radiance emitted by the surface and hence is an important boundary condition of the energy balance. In urban areas, detailed knowledge about the diurnal cycle in LST can contribute to understand the urban heat island (UHI). Although the increased surface temperatures compared to the surrounding rural areas (surface urban heat island, SUHI) have been measured by satellites and analysed for several decades, an operational SUHI monitoring is still not available due to the lack of sensors with appropriate spatiotemporal resolution. While sensors on polar orbiting satellites are still restricted to approx. 100 m spatial resolution and coarse temporal coverage (about 1-2 weeks), sensors on geostationary platforms have high temporal (several times per hour) and poor spatial resolution (>3 km). Further, all polar orbiting satellites have a similar equator crossing time and hence the SUHI can at best be observed at two times a day. A downscaling DS scheme for LST from the Spinning Enhanced Visible Infra-Red Imager (SEVIRI) sensor onboard the geostationary meteorological Meteosat 8 to spatial resolutions between 100 and 1000 m was developed and tested for Hamburg. Various data were tested as predictors, including multispectral data and derived indices, morphological parameters from interferometric SAR and multitemporal thermal data. All predictors were upscaled to the coarse resolution approximating the point spread function of SEVIRI. Then empirical relationships between the predictors and LST were derived which are then transferred to the high resolution domain, assuming they are scale invariant. For validation LST data from the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) and the Enhanced Thematic Mapper Plus (ETM+) for two dates were used. Aggregated parameters from multi-temporal thermal data (in particular annual cycle parameters and principal components) proved particularly suitable. The results for the highest resolution of 100 m showed a high explained variance (R^2 = 0.71) and relatively low root mean square errors (RMSE = 2.2 K) for the ASTER scene and slightly higher errors (R^2 = 0.73, RMSE = 2.53) for the ETM+ scene. A considerable percentage of the error was systematic due to the different viewing geometry of the sensors (the high resolution LST was overestimated about 1.3 K for ASTER and 0.66 K for ETM+). This shows that DS of SEVIRI LST is possible up to a resolution of 100 m for urban areas and that multitemporal thermal data are particularly suitable as predictors. Further, the scheme was used to produce an entire diurnal cycle in high resolution. While essential characteristics of the diurnal cycle were well reproduced, certain artefacts resulting from the multitemporal predictors from different seasons (like phenology and different water surface temperatures) were generated. Eventually, the bias and its dependence on the viewing geometry and topography are currently investigated.

  19. Super-resolution imaging of subcortical white matter using stochastic optical reconstruction microscopy (STORM) and super-resolution optical fluctuation imaging (SOFI)

    PubMed Central

    Hainsworth, A. H.; Lee, S.; Patel, A.; Poon, W. W.; Knight, A. E.

    2018-01-01

    Aims The spatial resolution of light microscopy is limited by the wavelength of visible light (the ‘diffraction limit’, approximately 250 nm). Resolution of sub-cellular structures, smaller than this limit, is possible with super resolution methods such as stochastic optical reconstruction microscopy (STORM) and super-resolution optical fluctuation imaging (SOFI). We aimed to resolve subcellular structures (axons, myelin sheaths and astrocytic processes) within intact white matter, using STORM and SOFI. Methods Standard cryostat-cut sections of subcortical white matter from donated human brain tissue and from adult rat and mouse brain were labelled, using standard immunohistochemical markers (neurofilament-H, myelin-associated glycoprotein, glial fibrillary acidic protein, GFAP). Image sequences were processed for STORM (effective pixel size 8–32 nm) and for SOFI (effective pixel size 80 nm). Results In human, rat and mouse, subcortical white matter high-quality images for axonal neurofilaments, myelin sheaths and filamentous astrocytic processes were obtained. In quantitative measurements, STORM consistently underestimated width of axons and astrocyte processes (compared with electron microscopy measurements). SOFI provided more accurate width measurements, though with somewhat lower spatial resolution than STORM. Conclusions Super resolution imaging of intact cryo-cut human brain tissue is feasible. For quantitation, STORM can under-estimate diameters of thin fluorescent objects. SOFI is more robust. The greatest limitation for super-resolution imaging in brain sections is imposed by sample preparation. We anticipate that improved strategies to reduce autofluorescence and to enhance fluorophore performance will enable rapid expansion of this approach. PMID:28696566

  20. Super-resolution imaging of subcortical white matter using stochastic optical reconstruction microscopy (STORM) and super-resolution optical fluctuation imaging (SOFI).

    PubMed

    Hainsworth, A H; Lee, S; Foot, P; Patel, A; Poon, W W; Knight, A E

    2018-06-01

    The spatial resolution of light microscopy is limited by the wavelength of visible light (the 'diffraction limit', approximately 250 nm). Resolution of sub-cellular structures, smaller than this limit, is possible with super resolution methods such as stochastic optical reconstruction microscopy (STORM) and super-resolution optical fluctuation imaging (SOFI). We aimed to resolve subcellular structures (axons, myelin sheaths and astrocytic processes) within intact white matter, using STORM and SOFI. Standard cryostat-cut sections of subcortical white matter from donated human brain tissue and from adult rat and mouse brain were labelled, using standard immunohistochemical markers (neurofilament-H, myelin-associated glycoprotein, glial fibrillary acidic protein, GFAP). Image sequences were processed for STORM (effective pixel size 8-32 nm) and for SOFI (effective pixel size 80 nm). In human, rat and mouse, subcortical white matter high-quality images for axonal neurofilaments, myelin sheaths and filamentous astrocytic processes were obtained. In quantitative measurements, STORM consistently underestimated width of axons and astrocyte processes (compared with electron microscopy measurements). SOFI provided more accurate width measurements, though with somewhat lower spatial resolution than STORM. Super resolution imaging of intact cryo-cut human brain tissue is feasible. For quantitation, STORM can under-estimate diameters of thin fluorescent objects. SOFI is more robust. The greatest limitation for super-resolution imaging in brain sections is imposed by sample preparation. We anticipate that improved strategies to reduce autofluorescence and to enhance fluorophore performance will enable rapid expansion of this approach. © 2017 British Neuropathological Society.

  1. Quantifying stream thermal regimes at management-pertinent scales: combining thermal infrared and stationary stream temperature data in a novel modeling framework.

    USGS Publications Warehouse

    Vatland, Shane J.; Gresswell, Robert E.; Poole, Geoffrey C.

    2015-01-01

    Accurately quantifying stream thermal regimes can be challenging because stream temperatures are often spatially and temporally heterogeneous. In this study, we present a novel modeling framework that combines stream temperature data sets that are continuous in either space or time. Specifically, we merged the fine spatial resolution of thermal infrared (TIR) imagery with hourly data from 10 stationary temperature loggers in a 100 km portion of the Big Hole River, MT, USA. This combination allowed us to estimate summer thermal conditions at a relatively fine spatial resolution (every 100 m of stream length) over a large extent of stream (100 km of stream) during during the warmest part of the summer. Rigorous evaluation, including internal validation, external validation with spatially continuous instream temperature measurements collected from a Langrangian frame of reference, and sensitivity analyses, suggests the model was capable of accurately estimating longitudinal patterns in summer stream temperatures for this system Results revealed considerable spatial and temporal heterogeneity in summer stream temperatures and highlighted the value of assessing thermal regimes at relatively fine spatial and temporal scales. Preserving spatial and temporal variability and structure in abiotic stream data provides a critical foundation for understanding the dynamic, multiscale habitat needs of mobile stream organisms. Similarly, enhanced understanding of spatial and temporal variation in dynamic water quality attributes, including temporal sequence and spatial arrangement, can guide strategic placement of monitoring equipment that will subsequently capture variation in environmental conditions directly pertinent to research and management objectives.

  2. Clinical utility of wavelet compression for resolution-enhanced chest radiography

    NASA Astrophysics Data System (ADS)

    Andriole, Katherine P.; Hovanes, Michael E.; Rowberg, Alan H.

    2000-05-01

    This study evaluates the usefulness of wavelet compression for resolution-enhanced storage phosphor chest radiographs in the detection of subtle interstitial disease, pneumothorax and other abnormalities. A wavelet compression technique, MrSIDTM (LizardTech, Inc., Seattle, WA), is implemented which compresses the images from their original 2,000 by 2,000 (2K) matrix size, and then decompresses the image data for display at optimal resolution by matching the spatial frequency characteristics of image objects using a 4,000- square matrix. The 2K-matrix computed radiography (CR) chest images are magnified to a 4K-matrix using wavelet series expansion. The magnified images are compared with the original uncompressed 2K radiographs and with two-times magnification of the original images. Preliminary results show radiologist preference for MrSIDTM wavelet-based magnification over magnification of original data, and suggest that the compressed/decompressed images may provide an enhancement to the original. Data collection for clinical trials of 100 chest radiographs including subtle interstitial abnormalities and/or subtle pneumothoraces and normal cases, are in progress. Three experienced thoracic radiologists will view images side-by- side on calibrated softcopy workstations under controlled viewing conditions, and rank order preference tests will be performed. This technique combines image compression with image enhancement, and suggests that compressed/decompressed images can actually improve the originals.

  3. Detector motion method to increase spatial resolution in photon-counting detectors

    NASA Astrophysics Data System (ADS)

    Lee, Daehee; Park, Kyeongjin; Lim, Kyung Taek; Cho, Gyuseong

    2017-03-01

    Medical imaging requires high spatial resolution of an image to identify fine lesions. Photon-counting detectors in medical imaging have recently been rapidly replacing energy-integrating detectors due to the former`s high spatial resolution, high efficiency and low noise. Spatial resolution in a photon counting image is determined by the pixel size. Therefore, the smaller the pixel size, the higher the spatial resolution that can be obtained in an image. However, detector redesigning is required to reduce pixel size, and an expensive fine process is required to integrate a signal processing unit with reduced pixel size. Furthermore, as the pixel size decreases, charge sharing severely deteriorates spatial resolution. To increase spatial resolution, we propose a detector motion method using a large pixel detector that is less affected by charge sharing. To verify the proposed method, we utilized a UNO-XRI photon-counting detector (1-mm CdTe, Timepix chip) at the maximum X-ray tube voltage of 80 kVp. A similar spatial resolution of a 55- μm-pixel image was achieved by application of the proposed method to a 110- μm-pixel detector with a higher signal-to-noise ratio. The proposed method could be a way to increase spatial resolution without a pixel redesign when pixels severely suffer from charge sharing as pixel size is reduced.

  4. Performance Evaluation of a New Dedicated Breast PET Scanner Using NEMA NU4-2008 Standards.

    PubMed

    Miyake, Kanae K; Matsumoto, Keiichi; Inoue, Mika; Nakamoto, Yuji; Kanao, Shotaro; Oishi, Tae; Kawase, Shigeto; Kitamura, Keishi; Yamakawa, Yoshiyuki; Akazawa, Ayako; Kobayashi, Tetsuya; Ohi, Junichi; Togashi, Kaori

    2014-07-01

    The aim of this work was to evaluate the performance characteristics of a newly developed dedicated breast PET scanner, according to National Electrical Manufacturers Association (NEMA) NU 4-2008 standards. The dedicated breast PET scanner consists of 4 layers of a 32 × 32 lutetium oxyorthosilicate-based crystal array, a light guide, and a 64-channel position-sensitive photomultiplier tube. The size of a crystal element is 1.44 × 1.44 × 4.5 mm. The detector ring has a large solid angle with a 185-mm aperture and an axial coverage of 155.5 mm. The energy windows at depth of interaction for the first and second layers are 400-800 keV, and those at the third and fourth layers are 100-800 keV. A fixed timing window of 4.5 ns was used for all acquisitions. Spatial resolution, sensitivity, counting rate capabilities, and image quality were evaluated in accordance with NEMA NU 4-2008 standards. Human imaging was performed in addition to the evaluation. Radial, tangential, and axial spatial resolution measured as minimal full width at half maximum approached 1.6, 1.7, and 2.0 mm, respectively, for filtered backprojection reconstruction and 0.8, 0.8, and 0.8 mm, respectively, for dynamic row-action maximum-likelihood algorithm reconstruction. The peak absolute sensitivity of the system was 11.2%. Scatter fraction at the same acquisition settings was 30.1% for the rat-sized phantom. Peak noise-equivalent counting rate and peak true rate for the ratlike phantom was 374 kcps at 25 MBq and 603 kcps at 31 MBq, respectively. In the image-quality phantom study, recovery coefficients and uniformity were 0.04-0.82 and 1.9%, respectively, for standard reconstruction mode and 0.09-0.97 and 4.5%, respectively, for enhanced-resolution mode. Human imaging provided high-contrast images with restricted background noise for standard reconstruction mode and high-resolution images for enhanced-resolution mode. The dedicated breast PET scanner has excellent spatial resolution and high sensitivity. The performance of the dedicated breast PET scanner is considered to be reasonable enough to support its use in breast cancer imaging. © 2014 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

  5. [Study of Image Quality Comparison Based on the MTF Method Between Different Medical Rigid Endoscopes in an In Vitro Model].

    PubMed

    Wang, Yunlong; Ji, Jun; Jiang, Changsong; Huang, Zengyue

    2015-04-01

    This study was aimed to use the method of modulation transfer function (MTF) to compare image quality among three different Olympus medical rigid cystoscopes in an in vitro model. During the experimental processes, we firstly used three different types of cystoscopes (i. e. OLYMPUS cystourethroscopy with FOV of 12 degrees, OLYMPUS Germany A22003A and OLYMPUS A2013A) to collect raster images at different brightness with industrial camera and computer from the resolution target which is with different spatial frequency, and then we processed the collected images using MALAB software with the optical transfer function MTF to obtain the values of MTF at different brightness and different spatial frequency. We then did data mathematical statistics and compared imaging quality. The statistical data showed that all three MTF values were smaller than 1. MTF values with the spatial frequency gradually increasing would decrease approaching 0 at the same brightness. When the brightness enhanced in the same process at the same spatial frequency, MTF values showed a slowly increasing trend. The three endoscopes' MTF values were completely different. In some cases the MTF values had a large difference, and the maximum difference could reach 0.7. Conclusion can be derived from analysis of experimental data that three Olympus medical rigid cystoscopes have completely different imaging quality abilities. The No. 3 endoscope OLYMPUS A2013A has low resolution but high contrast. The No. 1 endoscope OLYMPUS cystourethroscopy with FOV of 12 degrees, on the contrary, had high resolution and lower contrast. The No. 2 endoscope OLYMPUS Germany A22003A had high contrast and high resolution, and its image quality was the best.

  6. Resolving vorticity-driven lateral fire spread using the WRF-Fire coupled atmosphere-fire numerical model

    NASA Astrophysics Data System (ADS)

    Simpson, C. C.; Sharples, J. J.; Evans, J. P.

    2014-05-01

    Fire channelling is a form of dynamic fire behaviour, during which a wildland fire spreads rapidly across a steep lee-facing slope in a direction transverse to the background winds, and is often accompanied by a downwind extension of the active flaming region and extreme pyro-convection. Recent work using the WRF-Fire coupled atmosphere-fire model has demonstrated that fire channelling can be characterised as vorticity-driven lateral fire spread (VDLS). In this study, 16 simulations are conducted using WRF-Fire to examine the sensitivity of resolving VDLS to spatial resolution and atmosphere-fire coupling within the WRF-Fire model framework. The horizontal grid spacing is varied between 25 and 90 m, and the two-way atmosphere-fire coupling is either enabled or disabled. At high spatial resolution, the atmosphere-fire coupling increases the peak uphill and lateral spread rate by a factor of up to 2.7 and 9.5. The enhancement of the uphill and lateral spread rate diminishes at coarser spatial resolution, and VDLS is not modelled for a horizontal grid spacing of 90 m. The laterally spreading fire fronts become the dominant contributors of the extreme pyro-convection. The resolved fire-induced vortices responsible for driving the lateral spread in the coupled simulations have non-zero vorticity along each unit vector direction, and develop due to an interaction between the background winds and vertical return circulations generated at the flank of the fire front as part of the pyro-convective updraft. The results presented in this study demonstrate that both high spatial resolution and two-way atmosphere-fire coupling are required to reproduce VDLS within the current WRF-Fire model framework.

  7. Impact of high-resolution a priori profiles on satellite-based formaldehyde retrievals

    NASA Astrophysics Data System (ADS)

    Kim, Si-Wan; Natraj, Vijay; Lee, Seoyoung; Kwon, Hyeong-Ahn; Park, Rokjin; de Gouw, Joost; Frost, Gregory; Kim, Jhoon; Stutz, Jochen; Trainer, Michael; Tsai, Catalina; Warneke, Carsten

    2018-06-01

    Formaldehyde (HCHO) is either directly emitted from sources or produced during the oxidation of volatile organic compounds (VOCs) in the troposphere. It is possible to infer atmospheric HCHO concentrations using space-based observations, which may be useful for studying emissions and tropospheric chemistry at urban to global scales depending on the quality of the retrievals. In the near future, an unprecedented volume of satellite-based HCHO measurement data will be available from both geostationary and polar-orbiting platforms. Therefore, it is essential to develop retrieval methods appropriate for the next-generation satellites that measure at higher spatial and temporal resolution than the current ones. In this study, we examine the importance of fine spatial and temporal resolution a priori profile information on the retrieval by conducting approximately 45 000 radiative transfer (RT) model calculations in the Los Angeles Basin (LA Basin) megacity. Our analyses suggest that an air mass factor (AMF, a factor converting observed slant columns to vertical columns) based on fine spatial and temporal resolution a priori profiles can better capture the spatial distributions of the enhanced HCHO plumes in an urban area than the nearly constant AMFs used for current operational products by increasing the columns by ˜ 50 % in the domain average and up to 100 % at a finer scale. For this urban area, the AMF values are inversely proportional to the magnitude of the HCHO mixing ratios in the boundary layer. Using our optimized model HCHO results in the Los Angeles Basin that mimic the HCHO retrievals from future geostationary satellites, we illustrate the effectiveness of HCHO data from geostationary measurements for understanding and predicting tropospheric ozone and its precursors.

  8. Passive Microwave Remote Sensing of Colorado Watersheds Using Calibrated, Enhanced-Resolution Brightness Temperatures (CETB) from AMSR-E and SSM/I for Estimation of Snowmelt Timing

    NASA Astrophysics Data System (ADS)

    Johnson, M.; Ramage, J. M.; Troy, T. J.; Brodzik, M. J.

    2017-12-01

    Understanding the timing of snowmelt is critical for water resources management in snow-dominated watersheds. Passive microwave remote sensing has been used to estimate melt-refreeze events through brightness temperature satellite observations taken with sensors like the Special Sensor Microwave Imager (SSM/I) and the Advanced Microwave Scanning Radiometer - Earth Observing System (AMSR-E). Previous studies were limited to lower resolution ( 25 km) datasets, making it difficult to quantify the snowpack in heterogeneous, high-relief areas. This study investigates the use of newly available passive microwave calibrated, enhanced-resolution brightness temperatures (CETB) produced at the National Snow and Ice Data Center to estimate melt timing at much higher spatial resolution ( 3-6 km). CETB datasets generated from SSM/I and AMSR-E records will be used to examine three mountainous basins in Colorado. The CETB datasets retain twice-daily (day/night) observations of brightness temperatures. Therefore, we employ the diurnal amplitude variation (DAV) method to detect melt onset and melt occurrences to determine if algorithms developed for legacy data are valid with the improved CETB dataset. We compare melt variability with nearby stream discharge records to determine an optimum melt onset algorithm using the newly reprocessed data. This study investigates the effectiveness of the CETB product for several locations in Colorado (North Park, Rabbit Ears, Fraser) that were the sites of previous ground/airborne surveys during the NASA Cold Land Processes Field Experiment (CLPX 2002-2003). In summary, this work lays the foundation for the utilization of higher resolution reprocessed CETB data for snow evolution more broadly in a range of environments. Consequently, the new processing methods and improved spatial resolution will enable hydrologists to better analyze trends in snow-dominated mountainous watersheds for more effective water resources management.

  9. Reprocessing the Historical Satellite Passive Microwave Record at Enhanced Spatial Resolutions using Image Reconstruction

    NASA Astrophysics Data System (ADS)

    Hardman, M.; Brodzik, M. J.; Long, D. G.; Paget, A. C.; Armstrong, R. L.

    2015-12-01

    Beginning in 1978, the satellite passive microwave data record has been a mainstay of remote sensing of the cryosphere, providing twice-daily, near-global spatial coverage for monitoring changes in hydrologic and cryospheric parameters that include precipitation, soil moisture, surface water, vegetation, snow water equivalent, sea ice concentration and sea ice motion. Currently available global gridded passive microwave data sets serve a diverse community of hundreds of data users, but do not meet many requirements of modern Earth System Data Records (ESDRs) or Climate Data Records (CDRs), most notably in the areas of intersensor calibration, quality-control, provenance and consistent processing methods. The original gridding techniques were relatively primitive and were produced on 25 km grids using the original EASE-Grid definition that is not easily accommodated in modern software packages. Further, since the first Level 3 data sets were produced, the Level 2 passive microwave data on which they were based have been reprocessed as Fundamental CDRs (FCDRs) with improved calibration and documentation. We are funded by NASA MEaSUREs to reprocess the historical gridded data sets as EASE-Grid 2.0 ESDRs, using the most mature available Level 2 satellite passive microwave (SMMR, SSM/I-SSMIS, AMSR-E) records from 1978 to the present. We have produced prototype data from SSM/I and AMSR-E for the year 2003, for review and feedback from our Early Adopter user community. The prototype data set includes conventional, low-resolution ("drop-in-the-bucket" 25 km) grids and enhanced-resolution grids derived from the two candidate image reconstruction techniques we are evaluating: 1) Backus-Gilbert (BG) interpolation and 2) a radiometer version of Scatterometer Image Reconstruction (SIR). We summarize our temporal subsetting technique, algorithm tuning parameters and computational costs, and include sample SSM/I images at enhanced resolutions of up to 3 km. We are actively working with our Early Adopters to finalize content and format of this new, consistently-processed high-quality satellite passive microwave ESDR.

  10. Spatial entanglement patterns and Einstein-Podolsky-Rosen steering in Bose-Einstein condensates.

    PubMed

    Fadel, Matteo; Zibold, Tilman; Décamps, Boris; Treutlein, Philipp

    2018-04-27

    Many-particle entanglement is a fundamental concept of quantum physics that still presents conceptual challenges. Although nonclassical states of atomic ensembles were used to enhance measurement precision in quantum metrology, the notion of entanglement in these systems was debated because the correlations among the indistinguishable atoms were witnessed by collective measurements only. Here, we use high-resolution imaging to directly measure the spin correlations between spatially separated parts of a spin-squeezed Bose-Einstein condensate. We observe entanglement that is strong enough for Einstein-Podolsky-Rosen steering: We can predict measurement outcomes for noncommuting observables in one spatial region on the basis of corresponding measurements in another region with an inferred uncertainty product below the Heisenberg uncertainty bound. This method could be exploited for entanglement-enhanced imaging of electromagnetic field distributions and quantum information tasks. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

  11. Kernel temporal enhancement approach for LORETA source reconstruction using EEG data.

    PubMed

    Torres-Valencia, Cristian A; Santamaria, M Claudia Joana; Alvarez, Mauricio A

    2016-08-01

    Reconstruction of brain sources from magnetoencephalography and electroencephalography (M/EEG) data is a well known problem in the neuroengineering field. A inverse problem should be solved and several methods have been proposed. Low Resolution Electromagnetic Tomography (LORETA) and the different variations proposed as standardized LORETA (sLORETA) and the standardized weighted LORETA (swLORETA) have solved the inverse problem following a non-parametric approach, that is by setting dipoles in the whole brain domain in order to estimate the dipole positions from the M/EEG data and assuming some spatial priors. Errors in the reconstruction of sources are presented due the low spatial resolution of the LORETA framework and the influence of noise in the observable data. In this work a kernel temporal enhancement (kTE) is proposed in order to build a preprocessing stage of the data that allows in combination with the swLORETA method a improvement in the source reconstruction. The results are quantified in terms of three dipole error localization metrics and the strategy of swLORETA + kTE obtained the best results across different signal to noise ratio (SNR) in random dipoles simulation from synthetic EEG data.

  12. Phosphorescent probes for two-photon microscopy of oxygen (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Vinogradov, Sergei A.; Esipova, Tatiana V.

    2016-03-01

    The ability to quantify oxygen in vivo in 3D with high spatial and temporal resolution is much needed in many areas of biological research. Our laboratory has been developing the phosphorescence quenching technique for biological oximetry - an optical method that possesses intrinsic microscopic capability. In the past we have developed dendritically protected oxygen probes for quantitative imaging of oxygen in tissue. More recently we expanded our design on special two-photon enhanced phosphorescent probes. These molecules brought about first demonstrations of the two-photon phosphorescence lifetime microscopy (2PLM) of oxygen in vivo, providing new information for neouroscience and stem cell biology. However, current two-photon oxygen probes suffer from a number of limitations, such as sub-optimal brightness and high cost of synthesis, which dramatically reduce imaging performance and limit usability of the method. In this paper we discuss principles of 2PLM and address the interplay between the probe chemistry, photophysics and spatial and temporal imaging resolution. We then present a new approach to brightly phosphorescent chromophores with internally enhanced two-photon absorption cross-sections, which pave a way to a new generation of 2PLM probes.

  13. Near-field infrared vibrational dynamics and tip-enhanced decoherence.

    PubMed

    Xu, Xiaoji G; Raschke, Markus B

    2013-04-10

    Ultrafast infrared spectroscopy can reveal the dynamics of vibrational excitations in matter. In its conventional far-field implementation, however, it provides only limited insight into nanoscale sample volumes due to insufficient spatial resolution and sensitivity. Here, we combine scattering-scanning near-field optical microscopy (s-SNOM) with femtosecond infrared vibrational spectroscopy to characterize the coherent vibrational dynamics of a nanoscopic ensemble of C-F vibrational oscillators of polytetrafluoroethylene (PTFE). The near-field mode transfer between the induced vibrational molecular coherence and the metallic scanning probe tip gives rise to a tip-mediated radiative IR emission of the vibrational free-induction decay (FID). By increasing the tip–sample coupling, we can enhance the vibrational dephasing of the induced coherent vibrational polarization and associated IR emission, with dephasing times up to T2(NF) is approximately equal to 370 fs in competition against the intrinsic far-field lifetime of T2(FF) is approximately equal to 680 fs as dominated by nonradiative damping. Near-field antenna-coupling thus provides for a new way to modify vibrational decoherence. This approach of ultrafast s-SNOM enables the investigation of spatiotemporal dynamics and correlations with nanometer spatial and femtosecond temporal resolution.

  14. The value of Doppler LiDAR systems to monitor turbulence intensity during storm events in order to enhance aviation safety in Iceland

    NASA Astrophysics Data System (ADS)

    Yang, Shu; Nína Petersen, Guðrún; Finger, David C.

    2017-04-01

    Turbulence and wind shear are a major natural hazards for aviation safety in Iceland. The temporal and spatial scale of atmospheric turbulence is very dynamic, requiring an adequate method to detect and monitor turbulence with high resolution. The Doppler Light Detection and Ranging (LiDAR) system can provide continuous information about the wind field using the Doppler effect form emitted light signals. In this study, we use a Leosphere Windcube 200s LiDAR systems stationed near Reykjavik city Airport and at Keflavik International Airport, Iceland, to evaluate turbulence intensity by estimating eddy dissipation rate (EDR). For this purpose, we retrieved radial wind velocity observations from Velocity Azimuth Display (VAD) scans (360°scans at 15° and 75° elevation angle) to compute EDR. The method was used to monitor and characterize storm events in fall 2016 and the following winter. The preliminary result reveal that the LiDAR observations can detect and quantify atmospheric turbulence with high spatial and temporal resolution. This finding is an important step towards enhanced aviation safety in subpolar climate characterized by sever wind turbulence.

  15. Super-Resolution Enhancement From Multiple Overlapping Images: A Fractional Area Technique

    NASA Astrophysics Data System (ADS)

    Michaels, Joshua A.

    With the availability of large quantities of relatively low-resolution data from several decades of space borne imaging, methods of creating an accurate, higher-resolution image from the multiple lower-resolution images (i.e. super-resolution), have been developed almost since such imagery has been around. The fractional-area super-resolution technique developed in this thesis has never before been documented. Satellite orbits, like Landsat, have a quantifiable variation, which means each image is not centered on the exact same spot more than once and the overlapping information from these multiple images may be used for super-resolution enhancement. By splitting a single initial pixel into many smaller, desired pixels, a relationship can be created between them using the ratio of the area within the initial pixel. The ideal goal for this technique is to obtain smaller pixels with exact values and no error, yielding a better potential result than those methods that yield interpolated pixel values with consequential loss of spatial resolution. A Fortran 95 program was developed to perform all calculations associated with the fractional-area super-resolution technique. The fractional areas are calculated using traditional trigonometry and coordinate geometry and Linear Algebra Package (LAPACK; Anderson et al., 1999) is used to solve for the higher-resolution pixel values. In order to demonstrate proof-of-concept, a synthetic dataset was created using the intrinsic Fortran random number generator and Adobe Illustrator CS4 (for geometry). To test the real-life application, digital pictures from a Sony DSC-S600 digital point-and-shoot camera with a tripod were taken of a large US geological map under fluorescent lighting. While the fractional-area super-resolution technique works in perfect synthetic conditions, it did not successfully produce a reasonable or consistent solution in the digital photograph enhancement test. The prohibitive amount of processing time (up to 60 days for a relatively small enhancement area) severely limits the practical usefulness of fraction-area super-resolution. Fractional-area super-resolution is very sensitive to relative input image co-registration, which must be accurate to a sub-pixel degree. However, use of this technique, if input conditions permit, could be applied as a "pinpoint" super-resolution technique. Such an application could be possible by only applying it to only very small areas with very good input image co-registration.

  16. Improved scintimammography using a high-resolution camera mounted on an upright mammography gantry

    NASA Astrophysics Data System (ADS)

    Itti, Emmanuel; Patt, Bradley E.; Diggles, Linda E.; MacDonald, Lawrence; Iwanczyk, Jan S.; Mishkin, Fred S.; Khalkhali, Iraj

    2003-01-01

    99mTc-sestamibi scintimammography (SMM) is a useful adjunct to conventional X-ray mammography (XMM) for the assessment of breast cancer. An increasing number of studies has emphasized fair sensitivity values for the detection of tumors >1 cm, compared to XMM, particularly in situations where high glandular breast densities make mammographic interpretation difficult. In addition, SMM has demonstrated high specificity for cancer, compared to various functional and anatomic imaging modalities. However, large field-of-view (FOV) gamma cameras are difficult to position close to the breasts, which decreases spatial resolution and subsequently, the sensitivity of detection for tumors <1 cm. New dedicated detectors featuring small FOV and increased spatial resolution have recently been developed. In this setting, improvement in tumor detection sensitivity, particularly with regard to small cancers is expected. At Division of Nuclear Medicine, Harbor-UCLA Medical Center, we have performed over 2000 SMM within the last 9 years. We have recently used a dedicated breast camera (LumaGEM™) featuring a 12.8×12.8 cm 2 FOV and an array of 2×2×6 mm 3 discrete crystals coupled to a photon-sensitive photomultiplier tube readout. This camera is mounted on a mammography gantry allowing upright imaging, medial positioning and use of breast compression. Preliminary data indicates significant enhancement of spatial resolution by comparison with standard imaging in the first 10 patients. Larger series will be needed to conclude on sensitivity/specificity issues.

  17. Selecting a spatial resolution for estimation of per-field green leaf area index

    NASA Technical Reports Server (NTRS)

    Curran, Paul J.; Williamson, H. Dawn

    1988-01-01

    For any application of multispectral scanner (MSS) data, a user is faced with a number of choices concerning the characteristics of the data; one of these is their spatial resolution. A pilot study was undertaken to determine the spatial resolution that would be optimal for the per-field estimation of green leaf area index (GLAI) in grassland. By reference to empirically-derived data from three areas of grassland, the suitable spatial resolution was hypothesized to lie in the lower portion of a 2-18 m range. To estimate per-field GLAI, airborne MSS data were collected at spatial resolutions of 2 m, 5 m and 10 m. The highest accuracies of per-field GLAI estimation were achieved using MSS data with spatial resolutions of 2 m and 5 m.

  18. Spatial and Temporal Dust Source Variability in Northern China Identified Using Advanced Remote Sensing Analysis

    NASA Technical Reports Server (NTRS)

    Taramelli, A.; Pasqui, M.; Barbour, J.; Kirschbaum, D.; Bottai, L.; Busillo, C.; Calastrini, F.; Guarnieri, F.; Small, C.

    2013-01-01

    The aim of this research is to provide a detailed characterization of spatial patterns and temporal trends in the regional and local dust source areas within the desert of the Alashan Prefecture (Inner Mongolia, China). This problem was approached through multi-scale remote sensing analysis of vegetation changes. The primary requirements for this regional analysis are high spatial and spectral resolution data, accurate spectral calibration and good temporal resolution with a suitable temporal baseline. Landsat analysis and field validation along with the low spatial resolution classifications from MODIS and AVHRR are combined to provide a reliable characterization of the different potential dust-producing sources. The representation of intra-annual and inter-annual Normalized Difference Vegetation Index (NDVI) trend to assess land cover discrimination for mapping potential dust source using MODIS and AVHRR at larger scale is enhanced by Landsat Spectral Mixing Analysis (SMA). The combined methodology is to determine the extent to which Landsat can distinguish important soils types in order to better understand how soil reflectance behaves at seasonal and inter-annual timescales. As a final result mapping soil surface properties using SMA is representative of responses of different land and soil cover previously identified by NDVI trend. The results could be used in dust emission models even if they are not reflecting aggregate formation, soil stability or particle coatings showing to be critical for accurately represent dust source over different regional and local emitting areas.

  19. The influence of spatially and temporally high-resolution wind forcing on the power input to near-inertial waves in the ocean

    NASA Astrophysics Data System (ADS)

    Rimac, Antonija; von Storch, Jin-Song; Eden, Carsten

    2013-04-01

    The estimated power required to sustain global general circulation in the ocean is about 2 TW. This power is supplied with wind stress and tides. Energy spectrum shows pronounced maxima at near-inertial frequency. Near-inertial waves excited by high-frequency winds represent an important source for deep ocean mixing since they can propagate into the deep ocean and dissipate far away from the generation sites. The energy input by winds to near-inertial waves has been studied mostly using slab ocean models and wind stress forcing with coarse temporal resolution (e.g. 6-hourly). Slab ocean models lack the ability to reproduce fundamental aspects of kinetic energy balance and systematically overestimate the wind work. Also, slab ocean models do not account the energy used for the mixed layer deepening or the energy radiating downward into the deep ocean. Coarse temporal resolution of the wind forcing strongly underestimates the near-inertial energy. To overcome this difficulty we use an eddy permitting ocean model with high-frequency wind forcing. We establish the following model setup: We use the Max Planck Institute Ocean Model (MPIOM) on a tripolar grid with 45 km horizontal resolution and 40 vertical levels. We run the model with wind forcings that vary in horizontal and temporal resolution. We use high-resolution (1-hourly with 35 km horizontal resolution) and low-resolution winds (6-hourly with 250 km horizontal resolution). We address the following questions: Is the kinetic energy of near-inertial waves enhanced when high-resolution wind forcings are used? If so, is this due to higher level of overall wind variability or higher spatial or temporal resolution of wind forcing? How large is the power of near-inertial waves generated by winds? Our results show that near-inertial waves are enhanced and the near-inertial kinetic energy is two times higher (in the storm track regions 3.5 times higher) when high-resolution winds are used. Filtering high-resolution winds in space and time, the near-inertial kinetic energy reduces. The reduction is faster when a temporal filter is used suggesting that the high-frequency wind forcing is more efficient in generating near-inertial wave energy than the small-scale wind forcing. Using low-resolution wind forcing the wind generated power to near-inertial waves is 0.55 TW. When we use high-resolution wind forcing the result is 1.6 TW meaning that the result increases by 300%.

  20. Resolution enhancement of low-quality videos using a high-resolution frame

    NASA Astrophysics Data System (ADS)

    Pham, Tuan Q.; van Vliet, Lucas J.; Schutte, Klamer

    2006-01-01

    This paper proposes an example-based Super-Resolution (SR) algorithm of compressed videos in the Discrete Cosine Transform (DCT) domain. Input to the system is a Low-Resolution (LR) compressed video together with a High-Resolution (HR) still image of similar content. Using a training set of corresponding LR-HR pairs of image patches from the HR still image, high-frequency details are transferred from the HR source to the LR video. The DCT-domain algorithm is much faster than example-based SR in spatial domain 6 because of a reduction in search dimensionality, which is a direct result of the compact and uncorrelated DCT representation. Fast searching techniques like tree-structure vector quantization 16 and coherence search1 are also key to the improved efficiency. Preliminary results on MJPEG sequence show promising result of the DCT-domain SR synthesis approach.

  1. Superresolved digital in-line holographic microscopy for high-resolution lensless biological imaging

    NASA Astrophysics Data System (ADS)

    Micó, Vicente; Zalevsky, Zeev

    2010-07-01

    Digital in-line holographic microscopy (DIHM) is a modern approach capable of achieving micron-range lateral and depth resolutions in three-dimensional imaging. DIHM in combination with numerical imaging reconstruction uses an extremely simplified setup while retaining the advantages provided by holography with enhanced capabilities derived from algorithmic digital processing. We introduce superresolved DIHM incoming from time and angular multiplexing of the sample spatial frequency information and yielding in the generation of a synthetic aperture (SA). The SA expands the cutoff frequency of the imaging system, allowing submicron resolutions in both transversal and axial directions. The proposed approach can be applied when imaging essentially transparent (low-concentration dilutions) and static (slow dynamics) samples. Validation of the method for both a synthetic object (U.S. Air Force resolution test) to quantify the resolution improvement and a biological specimen (sperm cells biosample) are reported showing the generation of high synthetic numerical aperture values working without lenses.

  2. Tactile spatial resolution in blind braille readers.

    PubMed

    Van Boven, R W; Hamilton, R H; Kauffman, T; Keenan, J P; Pascual-Leone, A

    2000-06-27

    To determine if blind people have heightened tactile spatial acuity. Recently, studies using magnetic source imaging and somatosensory evoked potentials have shown that the cortical representation of the reading fingers of blind Braille readers is expanded compared to that of fingers of sighted subjects. Furthermore, the visual cortex is activated during certain tactile tasks in blind subjects but not sighted subjects. The authors hypothesized that the expanded cortical representation of fingers used in Braille reading may reflect an enhanced fidelity in the neural transmission of spatial details of a stimulus. If so, the quantitative limit of spatial acuity would be superior in blind people. The authors employed a grating orientation discrimination task in which threshold performance is accounted for by the spatial resolution limits of the neural image evoked by a stimulus. The authors quantified the psychophysical limits of spatial acuity at the middle and index fingers of 15 blind Braille readers and 15 sighted control subjects. The mean grating orientation threshold was significantly (p = 0.03) lower in the blind group (1.04 mm) compared to the sighted group (1.46 mm). The self-reported dominant reading finger in blind subjects had a mean grating orientation threshold of 0.80 mm, which was significantly better than other fingers tested. Thresholds at non-Braille reading fingers in blind subjects averaged 1.12 mm, which were also superior to sighted subjects' performances. Superior tactile spatial acuity in blind Braille readers may represent an adaptive, behavioral correlate of cortical plasticity.

  3. Forest Classification Accuracy as Influenced by Multispectral Scanner Spatial Resolution. [Sam Houston National Forest, Texas

    NASA Technical Reports Server (NTRS)

    Nalepka, R. F. (Principal Investigator); Sadowski, F. E.; Sarno, J. E.

    1976-01-01

    The author has identified the following significant results. A supervised classification within two separate ground areas of the Sam Houston National Forest was carried out for two sq meters spatial resolution MSS data. Data were progressively coarsened to simulate five additional cases of spatial resolution ranging up to 64 sq meters. Similar processing and analysis of all spatial resolutions enabled evaluations of the effect of spatial resolution on classification accuracy for various levels of detail and the effects on area proportion estimation for very general forest features. For very coarse resolutions, a subset of spectral channels which simulated the proposed thematic mapper channels was used to study classification accuracy.

  4. Image jitter enhances visual performance when spatial resolution is impaired.

    PubMed

    Watson, Lynne M; Strang, Niall C; Scobie, Fraser; Love, Gordon D; Seidel, Dirk; Manahilov, Velitchko

    2012-09-06

    Visibility of low-spatial frequency stimuli improves when their contrast is modulated at 5 to 10 Hz compared with stationary stimuli. Therefore, temporal modulations of visual objects could enhance the performance of low vision patients who primarily perceive images of low-spatial frequency content. We investigated the effect of retinal-image jitter on word recognition speed and facial emotion recognition in subjects with central visual impairment. Word recognition speed and accuracy of facial emotion discrimination were measured in volunteers with AMD under stationary and jittering conditions. Computer-driven and optoelectronic approaches were used to induce retinal-image jitter with duration of 100 or 166 ms and amplitude within the range of 0.5 to 2.6° visual angle. Word recognition speed was also measured for participants with simulated (Bangerter filters) visual impairment. Text jittering markedly enhanced word recognition speed for people with severe visual loss (101 ± 25%), while for those with moderate visual impairment, this effect was weaker (19 ± 9%). The ability of low vision patients to discriminate the facial emotions of jittering images improved by a factor of 2. A prototype of optoelectronic jitter goggles produced similar improvement in facial emotion discrimination. Word recognition speed in participants with simulated visual impairment was enhanced for interjitter intervals over 100 ms and reduced for shorter intervals. Results suggest that retinal-image jitter with optimal frequency and amplitude is an effective strategy for enhancing visual information processing in the absence of spatial detail. These findings will enable the development of novel tools to improve the quality of life of low vision patients.

  5. Digitally enhanced GLORIA images for petroleum exploration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Prindle, R.O.; Lanz, K

    1990-05-01

    This poster presentation graphically depicts the geological and structural information that can be derived from digitally enhanced Geological Long Range Inclined Asdic (GLORIA) sonar images. This presentation illustrates the advantages of scale enlargement as an interpreter's tool in an offshore area within the Eel River Basin, Northern California. Sonographs were produced from digital tapes originally collected for the exclusive economic zone (EEZ)-SCAN 1984 survey, which was published in the Atlas of the Western Conterminous US at a scale of 1:500,000. This scale is suitable for displaying regional offshore tectonic features but does not have the resolution required for detailed geologicalmore » mapping necessary for petroleum exploration. Applications of digital enhancing techniques which utilize contrast stretching and assign false colors to wide-swath sonar imagery (approximately 40 km) with 50-m resolution enables the acquisition and interpretation of significantly more geological and structural data. This, combined with a scale enlargement to 1:100,000 and high contrast contact prints vs. the offset prints of the atlas, increases the resolution and sharpness of bathymetric features so that many more subtle features may be mapped in detail. A tectonic interpretation of these digitally enhanced GLORIA sonographs from the Eel River basin is presented, displaying anticlines, lineaments, ridge axis, pathways of sediment flow, and subtle doming. Many of these features are not present on published bathymetric maps and have not been derived from seismic data because the plan view spatial resolution is much less than that available from the GLORIA imagery.« less

  6. Enhanced resolution and accuracy of freeform metrology through Subaperture Stitching Interferometry

    NASA Astrophysics Data System (ADS)

    Supranowitz, Chris; Maloney, Chris; Murphy, Paul; Dumas, Paul

    2017-10-01

    Recent advances in polishing and metrology have addressed many of the challenges in the fabrication and metrology of freeform surfaces, and the manufacture of these surfaces is possible today. However, achieving the form and mid-spatial frequency (MSF) specifications that are typical of visible imaging systems remains a challenge. Interferometric metrology for freeform surfaces is thus highly desirable for such applications, but the capability is currently quite limited for freeforms. In this paper, we provide preliminary results that demonstrate accurate, high-resolution measurements of freeform surfaces using prototype software on QED's ASI™ (Aspheric Stitching Interferometer).

  7. Equilibrium magnetic states in individual hemispherical permalloy caps

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Streubel, Robert; Schmidt, Oliver G.; Material Systems for Nanoelectronics, Chemnitz University of Technology, 09107 Chemnitz

    2012-09-24

    The magnetization distributions in individual soft magnetic permalloy caps on non-magnetic spherical particles with sizes ranging from 50 to 800 nm are investigated. We experimentally visualize the magnetic structures at the resolution limit of the x-ray magnetic circular dichroism photoelectron emission microscopy (XMCD-PEEM). By analyzing the so-called tail contrast in XMCD-PEEM, the spatial resolution is significantly enhanced, which allowed us to explore magnetic vortices and their displacement on curved surfaces. Furthermore, cap nanostructures are modeled as extruded hemispheres to determine theoretically the phase diagram of equilibrium magnetic states. The calculated phase diagram agrees well with the experimental observations.

  8. Efficient dynamic events discrimination technique for fiber distributed Brillouin sensors.

    PubMed

    Galindez, Carlos A; Madruga, Francisco J; Lopez-Higuera, Jose M

    2011-09-26

    A technique to detect real time variations of temperature or strain in Brillouin based distributed fiber sensors is proposed and is investigated in this paper. The technique is based on anomaly detection methods such as the RX-algorithm. Detection and isolation of dynamic events from the static ones are demonstrated by a proper processing of the Brillouin gain values obtained by using a standard BOTDA system. Results also suggest that better signal to noise ratio, dynamic range and spatial resolution can be obtained. For a pump pulse of 5 ns the spatial resolution is enhanced, (from 0.541 m obtained by direct gain measurement, to 0.418 m obtained with the technique here exposed) since the analysis is concentrated in the variation of the Brillouin gain and not only on the averaging of the signal along the time. © 2011 Optical Society of America

  9. An Iterated Global Mascon Solution with Focus on Land Ice Mass Evolution

    NASA Technical Reports Server (NTRS)

    Luthcke, S. B.; Sabaka, T.; Rowlands, D. D.; Lemoine, F. G.; Loomis, B. D.; Boy, J. P.

    2012-01-01

    Land ice mass evolution is determined from a new GRACE global mascon solution. The solution is estimated directly from the reduction of the inter-satellite K-band range rate observations taking into account the full noise covariance, and formally iterating the solution. The new solution increases signal recovery while reducing the GRACE KBRR observation residuals. The mascons are estimated with 10-day and 1-arc-degree equal area sampling, applying anisotropic constraints for enhanced temporal and spatial resolution of the recovered land ice signal. The details of the solution are presented including error and resolution analysis. An Ensemble Empirical Mode Decomposition (EEMD) adaptive filter is applied to the mascon solution time series to compute timing of balance seasons and annual mass balances. The details and causes of the spatial and temporal variability of the land ice regions studied are discussed.

  10. Coi-wiz: An interactive computer wizard for analyzing cardiac optical signals.

    PubMed

    Yuan, Xiaojing; Uyanik, Ilyas; Situ, Ning; Xi, Yutao; Cheng, Jie

    2009-01-01

    A number of revolutionary techniques have been developed for cardiac electrophysiology research to better study the various arrhythmia mechanisms that can enhance ablating strategies for cardiac arrhythmias. Once the three-dimensional high resolution cardiac optical imaging data is acquired, it is time consuming to manually go through them and try to identify the patterns associated with various arrhythmia symptoms. In this paper, we present an interactive computer wizard that helps cardiac electrophysiology researchers to visualize and analyze the high resolution cardiac optical imaging data. The wizard provides a file interface that accommodates different file formats. A series of analysis algorithms output waveforms, activation and action potential maps after spatial and temporal filtering, velocity field and heterogeneity measure. The interactive GUI allows the researcher to identify the region of interest in both the spatial and temporal domain, thus enabling them to study different heart chamber at their choice.

  11. High contrast computed tomography with synchrotron radiation

    NASA Astrophysics Data System (ADS)

    Itai, Yuji; Takeda, Tohoru; Akatsuka, Takao; Maeda, Tomokazu; Hyodo, Kazuyuki; Uchida, Akira; Yuasa, Tetsuya; Kazama, Masahiro; Wu, Jin; Ando, Masami

    1995-02-01

    This article describes a new monochromatic x-ray CT system using synchrotron radiation with applications in biomedical diagnosis which is currently under development. The system is designed to provide clear images and to detect contrast materials at low concentration for the quantitative functional evaluation of organs in correspondence with their anatomical structures. In this system, with x-ray energy changing from 30 to 52 keV, images can be obtained to detect various contrast materials (iodine, barium, and gadolinium), and K-edge energy subtraction is applied. Herein, the features of the new system designed to enhance the advantages of SR are reported. With the introduction of a double-crystal monochromator, the high-order x-ray contamination is eliminated. The newly designed CCD detector with a wide dynamic range of 60 000:1 has a spatial resolution of 200 μm. The resulting image quality, which is expected to show improved contrast and spatial resolution, is currently under investigation.

  12. Evaluation of fast highly undersampled contrast-enhanced MR angiography (sparse CE-MRA) in intracranial applications - initial study.

    PubMed

    Gratz, Marcel; Schlamann, Marc; Goericke, Sophia; Maderwald, Stefan; Quick, Harald H

    2017-03-01

    To assess the image quality of sparsely sampled contrast-enhanced MR angiography (sparse CE-MRA) providing high spatial resolution and whole-head coverage. Twenty-three patients scheduled for contrast-enhanced MR imaging of the head, (N = 19 with intracranial pathologies, N = 9 with vascular diseases), were included. Sparse CE-MRA at 3 Tesla was conducted using a single dose of contrast agent. Two neuroradiologists independently evaluated the data regarding vascular visibility and diagnostic value of overall 24 parameters and vascular segments on a 5-point ordinary scale (5 = very good, 1 = insufficient vascular visibility). Contrast bolus timing and the resulting arterio-venous overlap was also evaluated. Where available (N = 9), sparse CE-MRA was compared to intracranial Time-of-Flight MRA. The overall rating across all patients for sparse CE-MRA was 3.50 ± 1.07. Direct influence of the contrast bolus timing on the resulting image quality was observed. Overall mean vascular visibility and image quality across different features was rated good to intermediate (3.56 ± 0.95). The average performance of intracranial Time-of-Flight was rated 3.84 ± 0.87 across all patients and 3.54 ± 0.62 across all features. Sparse CE-MRA provides high-quality 3D MRA with high spatial resolution and whole-head coverage within short acquisition time. Accurate contrast bolus timing is mandatory. • Sparse CE-MRA enables fast vascular imaging with full brain coverage. • Volumes with sub-millimetre resolution can be acquired within 10 seconds. • Reader's ratings are good to intermediate and dependent on contrast bolus timing. • The method provides an excellent overview and allows screening for vascular pathologies.

  13. High Resolution Mesoscale Weather Data Improvement to Spatial Effects for Dose-Rate Contour Plot Predictions

    DTIC Science & Technology

    2007-03-01

    time. This is a very powerful tool in determining fine spatial resolution , as boundary conditions are not only updated at every timestep, but the ...HIGH RESOLUTION MESOSCALE WEATHER DATA IMPROVEMENT TO SPATIAL EFFECTS FOR DOSE-RATE CONTOUR PLOT PREDICTIONS THESIS Christopher P...11 1 HIGH RESOLUTION MESOSCALE WEATHER DATA IMPROVEMENT TO SPATIAL EFFECTS FOR DOSE-RATE CONTOUR PLOT

  14. Object-based methods for individual tree identification and tree species classification from high-spatial resolution imagery

    NASA Astrophysics Data System (ADS)

    Wang, Le

    2003-10-01

    Modern forest management poses an increasing need for detailed knowledge of forest information at different spatial scales. At the forest level, the information for tree species assemblage is desired whereas at or below the stand level, individual tree related information is preferred. Remote Sensing provides an effective tool to extract the above information at multiple spatial scales in the continuous time domain. To date, the increasing volume and readily availability of high-spatial-resolution data have lead to a much wider application of remotely sensed products. Nevertheless, to make effective use of the improving spatial resolution, conventional pixel-based classification methods are far from satisfactory. Correspondingly, developing object-based methods becomes a central challenge for researchers in the field of Remote Sensing. This thesis focuses on the development of methods for accurate individual tree identification and tree species classification. We develop a method in which individual tree crown boundaries and treetop locations are derived under a unified framework. We apply a two-stage approach with edge detection followed by marker-controlled watershed segmentation. Treetops are modeled from radiometry and geometry aspects. Specifically, treetops are assumed to be represented by local radiation maxima and to be located near the center of the tree-crown. As a result, a marker image was created from the derived treetop to guide a watershed segmentation to further differentiate overlapping trees and to produce a segmented image comprised of individual tree crowns. The image segmentation method developed achieves a promising result for a 256 x 256 CASI image. Then further effort is made to extend our methods to the multiscales which are constructed from a wavelet decomposition. A scale consistency and geometric consistency are designed to examine the gradients along the scale-space for the purpose of separating true crown boundary from unwanted textures occurring due to branches and twigs. As a result from the inverse wavelet transform, the tree crown boundary is enhanced while the unwanted textures are suppressed. Based on the enhanced image, an improvement is achieved when applying the two-stage methods to a high resolution aerial photograph. To improve tree species classification, we develop a new method to choose the optimal scale parameter with the aid of Bhattacharya Distance (BD), a well-known index of class separability in traditional pixel-based classification. The optimal scale parameter is then fed in the process of a region-growing-based segmentation as a break-off value. Our object classification achieves a better accuracy in separating tree species when compared to the conventional Maximum Likelihood Classification (MLC). In summary, we develop two object-based methods for identifying individual trees and classifying tree species from high-spatial resolution imagery. Both methods achieve promising results and will promote integration of Remote Sensing and GIS in forest applications.

  15. Tip-enhanced near-field optical microscopy

    PubMed Central

    Mauser, Nina; Hartschuh, Achim

    2013-01-01

    Tip-enhanced near-field optical microscopy (TENOM) is a scanning probe technique capable of providing a broad range of spectroscopic information on single objects and structured surfaces at nanometer spatial resolution and with highest detection sensitivity. In this review, we first illustrate the physical principle of TENOM that utilizes the antenna function of a sharp probe to efficiently couple light to excitations on nanometer length scales. We then discuss the antenna-induced enhancement of different optical sample responses including Raman scattering, fluorescence, generation of photocurrent and electroluminescence. Different experimental realizations are presented and several recent examples that demonstrate the capabilities of the technique are reviewed. PMID:24100541

  16. Isotropic image in structured illumination microscopy patterned with a spatial light modulator.

    PubMed

    Chang, Bo-Jui; Chou, Li-Jun; Chang, Yun-Ching; Chiang, Su-Yu

    2009-08-17

    We developed a structured illumination microscopy (SIM) system that uses a spatial light modulator (SLM) to generate interference illumination patterns at four orientations - 0 degrees, 45 degrees, 90 degrees, and 135 degrees, to reconstruct a high-resolution image. The use of a SLM for pattern alterations is rapid and precise, without mechanical calibration; moreover, our design of SLM patterns allows generating the four illumination patterns of high contrast and nearly equivalent periods to achieve a near isotropic enhancement in lateral resolution. We compare the conventional image of 100-nm beads with those reconstructed from two (0 degrees +90 degrees or 45 degrees +135 degrees) and four (0 degrees +45 degrees +90 degrees +135 degrees) pattern orientations to show the differences in resolution and image, with the support of simulations. The reconstructed images of 200-nm beads at various depths and fine structures of actin filaments near the edge of a HeLa cell are presented to demonstrate the intensity distributions in the axial direction and the prospective application to biological systems. (c) 2009 Optical Society of America

  17. Comparison of one- and two-photon optical beam-induced current imaging

    NASA Astrophysics Data System (ADS)

    Xu, Chris; Denk, Winfried

    1999-08-01

    Optical beam induced current (OBIC) imaging through the backside of integrated circuits was investigated in the wavelength λ region from 1.15 to 1.26 μm. With a subpicosecond excitation source and approximately 1 mW at the sample, the two-photon contribution to the generated photocurrent dominates at λ=1.25 μm but becomes negligible for λ<1.18 μm. One-photon- (1P-) and two-photon- (2P-) OBIC images are very different. In the 1P case a strong contribution by scattered light to the carrier generation leads to an edge enhancement effect that is entirely missing when 2P excitation dominates. 2P-OBIC images often show supply-voltage dependent intensity steps that are much sharper than the optical resolution permits. The advantages of 2P-OBIC lie in the spatial confinement of the free carrier generation, a more relevant contrast mechanism, and the promise of a substantial increase in spatial resolution because of the quadratic intensity dependence and the possibility of using silicon solid immersion lenses, which could eventually provide resolution sufficient for circuits made by deep UV lithography.

  18. High-resolution multi-code implementation of unsteady Navier-Stokes flow solver based on paralleled overset adaptive mesh refinement and high-order low-dissipation hybrid schemes

    NASA Astrophysics Data System (ADS)

    Li, Gaohua; Fu, Xiang; Wang, Fuxin

    2017-10-01

    The low-dissipation high-order accurate hybrid up-winding/central scheme based on fifth-order weighted essentially non-oscillatory (WENO) and sixth-order central schemes, along with the Spalart-Allmaras (SA)-based delayed detached eddy simulation (DDES) turbulence model, and the flow feature-based adaptive mesh refinement (AMR), are implemented into a dual-mesh overset grid infrastructure with parallel computing capabilities, for the purpose of simulating vortex-dominated unsteady detached wake flows with high spatial resolutions. The overset grid assembly (OGA) process based on collection detection theory and implicit hole-cutting algorithm achieves an automatic coupling for the near-body and off-body solvers, and the error-and-try method is used for obtaining a globally balanced load distribution among the composed multiple codes. The results of flows over high Reynolds cylinder and two-bladed helicopter rotor show that the combination of high-order hybrid scheme, advanced turbulence model, and overset adaptive mesh refinement can effectively enhance the spatial resolution for the simulation of turbulent wake eddies.

  19. Demonstration of a large-size horizontal light-field display based on the LED panel and the micro-pinhole unit array

    NASA Astrophysics Data System (ADS)

    Yang, Le; Sang, Xinzhu; Yu, Xunbo; Liu, Boyang; Liu, Li; Yang, Shenwu; Yan, Binbin; Du, Jingyan; Gao, Chao

    2018-05-01

    A 54-inch horizontal-parallax only light-field display based on the light-emitting diode (LED) panel and the micro-pinhole unit array (MPUA) is demonstrated. Normally, the perceived 3D effect of the three-dimensional (3D) display with smooth motion parallax and abundant light-field information can be enhanced with increasing the density of viewpoints. However, the density of viewpoints is inversely proportional to the spatial display resolution for the conventional integral imaging. Here, a special MPUA is designed and fabricated, and the displayed 3D scene constructed by the proposed horizontal light-field display is presented. Compared with the conventional integral imaging, both the density of horizontal viewpoints and the spatial display resolution are significantly improved. In the experiment, A 54-inch horizontal light-field display with 42.8° viewing angle based on the LED panel with the resolution of 1280 × 720 and the MPUA is realized, which can provide natural 3D visual effect to observers with high quality.

  20. Carbon Nanotubes as an Ultrafast Emitter with a Narrow Energy Spread at Optical Frequency.

    PubMed

    Li, Chi; Zhou, Xu; Zhai, Feng; Li, Zhenjun; Yao, Fengrui; Qiao, Ruixi; Chen, Ke; Cole, Matthew Thomas; Yu, Dapeng; Sun, Zhipei; Liu, Kaihui; Dai, Qing

    2017-08-01

    Ultrafast electron pulses, combined with laser-pump and electron-probe technologies, allow ultrafast dynamics to be characterized in materials. However, the pursuit of simultaneous ultimate spatial and temporal resolution of microscopy and spectroscopy is largely subdued by the low monochromaticity of the electron pulses and their poor phase synchronization to the optical excitation pulses. Field-driven photoemission from metal tips provides high light-phase synchronization, but suffers large electron energy spreads (3-100 eV) as driven by a long wavelength laser (>800 nm). Here, ultrafast electron emission from carbon nanotubes (≈1 nm radius) excited by a 410 nm femtosecond laser is realized in the field-driven regime. In addition, the emitted electrons have great monochromaticity with energy spread as low as 0.25 eV. This great performance benefits from the extraordinarily high field enhancement and great stability of carbon nanotubes, superior to metal tips. The new nanotube-based ultrafast electron source opens exciting prospects for extending current characterization to sub-femtosecond temporal resolution as well as sub-nanometer spatial resolution. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. New technology and techniques for x-ray mirror calibration at PANTER

    NASA Astrophysics Data System (ADS)

    Freyberg, Michael J.; Budau, Bernd; Burkert, Wolfgang; Friedrich, Peter; Hartner, Gisela; Misaki, Kazutami; Mühlegger, Martin

    2008-07-01

    The PANTER X-ray Test Facility has been utilized successfully for developing and calibrating X-ray astronomical instrumentation for observatories such as ROSAT, Chandra, XMM-Newton, Swift, etc. Future missions like eROSITA, SIMBOL-X, or XEUS require improved spatial resolution and broader energy band pass, both for optics and for cameras. Calibration campaigns at PANTER have made use of flight spare instrumentation for space applications; here we report on a new dedicated CCD camera for on-ground calibration, called TRoPIC. As the CCD is similar to ones used for eROSITA (pn-type, back-illuminated, 75 μm pixel size, frame store mode, 450 μm micron wafer thickness, etc.) it can serve as prototype for eROSITA camera development. New techniques enable and enhance the analysis of measurements of eROSITA shells or silicon pore optics. Specifically, we show how sub-pixel resolution can be utilized to improve spatial resolution and subsequently the characterization of of mirror shell quality and of point spread function parameters in particular, also relevant for position reconstruction of astronomical sources in orbit.

  2. Impact of the spatial resolution of satellite remote sensing sensors in the quantification of total suspended sediment concentration: A case study in turbid waters of Northern Western Australia.

    PubMed

    Dorji, Passang; Fearns, Peter

    2017-01-01

    The impact of anthropogenic activities on coastal waters is a cause of concern because such activities add to the total suspended sediment (TSS) budget of the coastal waters, which have negative impacts on the coastal ecosystem. Satellite remote sensing provides a powerful tool in monitoring TSS concentration at high spatiotemporal resolution, but coastal managers should be mindful that the satellite-derived TSS concentrations are dependent on the satellite sensor's radiometric properties, atmospheric correction approaches, the spatial resolution and the limitations of specific TSS algorithms. In this study, we investigated the impact of different spatial resolutions of satellite sensor on the quantification of TSS concentration in coastal waters of northern Western Australia. We quantified the TSS product derived from MODerate resolution Imaging Spectroradiometer (MODIS)-Aqua, Landsat-8 Operational Land Image (OLI), and WorldView-2 (WV2) at native spatial resolutions of 250 m, 30 m and 2 m respectively and coarser spatial resolution (resampled up to 5 km) to quantify the impact of spatial resolution on the derived TSS product in different turbidity conditions. The results from the study show that in the waters of high turbidity and high spatial variability, the high spatial resolution WV2 sensor reported TSS concentration as high as 160 mg L-1 while the low spatial resolution MODIS-Aqua reported a maximum TSS concentration of 23.6 mg L-1. Degrading the spatial resolution of each satellite sensor for highly spatially variable turbid waters led to variability in the TSS concentrations of 114.46%, 304.68% and 38.2% for WV2, Landsat-8 OLI and MODIS-Aqua respectively. The implications of this work are particularly relevant in the situation of compliance monitoring where operations may be required to restrict TSS concentrations to a pre-defined limit.

  3. Impact of the spatial resolution of satellite remote sensing sensors in the quantification of total suspended sediment concentration: A case study in turbid waters of Northern Western Australia

    PubMed Central

    Fearns, Peter

    2017-01-01

    The impact of anthropogenic activities on coastal waters is a cause of concern because such activities add to the total suspended sediment (TSS) budget of the coastal waters, which have negative impacts on the coastal ecosystem. Satellite remote sensing provides a powerful tool in monitoring TSS concentration at high spatiotemporal resolution, but coastal managers should be mindful that the satellite-derived TSS concentrations are dependent on the satellite sensor’s radiometric properties, atmospheric correction approaches, the spatial resolution and the limitations of specific TSS algorithms. In this study, we investigated the impact of different spatial resolutions of satellite sensor on the quantification of TSS concentration in coastal waters of northern Western Australia. We quantified the TSS product derived from MODerate resolution Imaging Spectroradiometer (MODIS)-Aqua, Landsat-8 Operational Land Image (OLI), and WorldView-2 (WV2) at native spatial resolutions of 250 m, 30 m and 2 m respectively and coarser spatial resolution (resampled up to 5 km) to quantify the impact of spatial resolution on the derived TSS product in different turbidity conditions. The results from the study show that in the waters of high turbidity and high spatial variability, the high spatial resolution WV2 sensor reported TSS concentration as high as 160 mg L-1 while the low spatial resolution MODIS-Aqua reported a maximum TSS concentration of 23.6 mg L-1. Degrading the spatial resolution of each satellite sensor for highly spatially variable turbid waters led to variability in the TSS concentrations of 114.46%, 304.68% and 38.2% for WV2, Landsat-8 OLI and MODIS-Aqua respectively. The implications of this work are particularly relevant in the situation of compliance monitoring where operations may be required to restrict TSS concentrations to a pre-defined limit. PMID:28380059

  4. Attention Modifies Spatial Resolution According to Task Demands.

    PubMed

    Barbot, Antoine; Carrasco, Marisa

    2017-03-01

    How does visual attention affect spatial resolution? In texture-segmentation tasks, exogenous (involuntary) attention automatically increases resolution at the attended location, which improves performance where resolution is too low (at the periphery) but impairs performance where resolution is already too high (at central locations). Conversely, endogenous (voluntary) attention improves performance at all eccentricities, which suggests a more flexible mechanism. Here, using selective adaptation to spatial frequency, we investigated the mechanism by which endogenous attention benefits performance in resolution tasks. Participants detected a texture target that could appear at several eccentricities. Adapting to high or low spatial frequencies selectively affected performance in a manner consistent with changes in resolution. Moreover, adapting to high, but not low, frequencies mitigated the attentional benefit at central locations where resolution was too high; this shows that attention can improve performance by decreasing resolution. Altogether, our results indicate that endogenous attention benefits performance by modulating the contribution of high-frequency information in order to flexibly adjust spatial resolution according to task demands.

  5. Attention Modifies Spatial Resolution According to Task Demands

    PubMed Central

    Barbot, Antoine; Carrasco, Marisa

    2017-01-01

    How does visual attention affect spatial resolution? In texture-segmentation tasks, exogenous (involuntary) attention automatically increases resolution at the attended location, which improves performance where resolution is too low (at the periphery) but impairs performance where resolution is already too high (at central locations). Conversely, endogenous (voluntary) attention improves performance at all eccentricities, which suggests a more flexible mechanism. Here, using selective adaptation to spatial frequency, we investigated the mechanism by which endogenous attention benefits performance in resolution tasks. Participants detected a texture target that could appear at several eccentricities. Adapting to high or low spatial frequencies selectively affected performance in a manner consistent with changes in resolution. Moreover, adapting to high, but not low, frequencies mitigated the attentional benefit at central locations where resolution was too high; this shows that attention can improve performance by decreasing resolution. Altogether, our results indicate that endogenous attention benefits performance by modulating the contribution of high-frequency information in order to flexibly adjust spatial resolution according to task demands. PMID:28118103

  6. Infrared absorption spectroscopy and sensing of protein monolayers using high performance enhancing substrates and a mobile phone (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Dana, Aykutlu; Ayas, Sencer; Bakan, Gokhan; Ozgur, Erol; Guner, Hasan; Celebi, Kemal

    2016-09-01

    Infrared absorption spectroscopy has greatly benefited from the electromagnetic field enhancement offered by plasmonic surfaces. However, because of the localized nature of plasmonic fields, such field enhancements are limited to nm-scale volumes. Here, we demonstrate that a relatively small, but spatially-uniform field enhancement can yield a superior infrared detection performance compared to the plasmonic field enhancement exhibited by optimized infrared nanoantennas. A specifically designed CaF2/Al thin film surface is shown to enable observation of stronger vibrational signals from the probe material, with wider bandwidth and a deeper spatial extent of the field enhancement as compared to optimized plasmonic surfaces. It is demonstrated that the surface structure presented here can enable chemically specific and label-free detection of organic monolayers using surface enhanced infrared spectroscopy. Also, a low cost hand held infrared absorption measurement setup is demonstrated using a miniature bolometric sensor and a mobile phone. A specifically designed grating in combination with an IR light source yields an IR spectrometer covering 7-12 um range, with about 100 cm-1 resolution. Combining the enhancing substrates with the spectroscopy setup, low cost, high sensitivity mobile infrared sensing is enabled. The results have implications in homeland security and environmental monitoring as well as chemical analysis.

  7. Multiresolution quantification of deciduousness in West-Central African forests

    NASA Astrophysics Data System (ADS)

    Viennois, G.; Barbier, N.; Fabre, I.; Couteron, P.

    2013-11-01

    The characterization of leaf phenology in tropical forests is of major importance for forest typology as well as to improve our understanding of earth-atmosphere-climate interactions or biogeochemical cycles. The availability of satellite optical data with a high temporal resolution has permitted the identification of unexpected phenological cycles, particularly over the Amazon region. A primary issue in these studies is the relationship between the optical reflectance of pixels of 1 km or more in size and ground information of limited spatial extent. In this paper, we demonstrate that optical data with high to very-high spatial resolution can help bridge this scale gap by providing snapshots of the canopy that allow discernment of the leaf-phenological stage of trees and the proportions of leaved crowns within the canopy. We also propose applications for broad-scale forest characterization and mapping in West-Central Africa over an area of 141 000 km2. Eleven years of the Moderate Resolution Imaging Spectroradiometer (MODIS) Enhanced Vegetation Index (EVI) data were averaged over the wet and dry seasons to provide a data set of optimal radiometric quality at a spatial resolution of 250 m. Sample areas covered at a very-high (GeoEye) and high (SPOT-5) spatial resolution were used to identify forest types and to quantify the proportion of leaved trees in the canopy. The dry-season EVI was positively correlated with the proportion of leaved trees in the canopy. This relationship allowed the conversion of EVI into canopy deciduousness at the regional level. On this basis, ecologically important forest types could be mapped, including young secondary, open Marantaceae, Gilbertiodendron dewevrei and swamp forests. We show that in West-Central African forests, a large share of the variability in canopy reflectance, as captured by the EVI, is due to variation in the proportion of leaved trees in the upper canopy, thereby opening new perspectives for biodiversity and carbon-cycle applications.

  8. Multiresolution quantification of deciduousness in West Central African forests

    NASA Astrophysics Data System (ADS)

    Viennois, G.; Barbier, N.; Fabre, I.; Couteron, P.

    2013-04-01

    The characterization of leaf phenology in tropical forests is of major importance and improves our understanding of earth-atmosphere-climate interactions. The availability of satellite optical data with a high temporal resolution has permitted the identification of unexpected phenological cycles, particularly over the Amazon region. A primary issue in these studies is the relationship between the optical reflectance of pixels of 1 km or more in size and ground information of limited spatial extent. In this paper, we demonstrate that optical data with high to very-high spatial resolution can help bridge this scale gap by providing snapshots of the canopy that allow discernment of the leaf-phenological stage of trees and the proportions of leaved crowns within the canopy. We also propose applications for broad-scale forest characterization and mapping in West Central Africa over an area of 141 000 km2. Eleven years of the Moderate Resolution Imaging Spectroradiometer (MODIS) Enhanced Vegetation Index (EVI) data were averaged over the wet and dry seasons to provide a dataset of optimal radiometric quality at a spatial resolution of 250 m. Sample areas covered at a very-high (GeoEye) and high (SPOT-5) spatial resolution were used to identify forest types and to quantify the proportion of leaved trees in the canopy. The dry season EVI was positively correlated with the proportion of leaved trees in the canopy. This relationship allowed the conversion of EVI into canopy deciduousness at the regional level. On this basis, ecologically important forest types could be mapped, including young secondary, open Marantaceae, Gilbertiodendron dewevrei and swamp forests. We show that in west central African forests, a large share of the variability in canopy reflectance, as captured by the EVI, is due to variation in the proportion of leaved trees in the upper canopy, thereby opening new perspectives for biodiversity and carbon-cycle applications.

  9. Phenological monitoring of Acadia National Park using Landsat, MODIS and VIIRS observations and fused data

    NASA Astrophysics Data System (ADS)

    Liu, Y.; McDonough MacKenzie, C.; Primack, R.; Zhang, X.; Schaaf, C.; Sun, Q.; Wang, Z.

    2015-12-01

    Monitoring phenology with remotely sensed data has become standard practice in large-plot agriculture but remains an area of research in complex terrain. Landsat data (30m) provides a more appropriate spatial resolution to describe such regions but may only capture a few cloud-free images over a growing period. Daily data from the MODerate resolution Imaging Spectroradiometer(MODIS) and Visible Infrared Imaging Radiometer Suite(VIIRS) offer better temporal acquisitions but at coarse spatial resolutions of 250m to 1km. Thus fused data sets are being employed to provide the temporal and spatial resolutions necessary to accurately monitor vegetation phenology. This study focused on Acadia National Park, Maine, attempts to compare green-up from remote sensing and ground observations over varying topography. Three north-south field transects were established in 2013 on parallel mountains. Along these transects, researchers record the leaf out and flowering phenology for thirty plant species biweekly. These in situ spring phenological observations are compared with the dates detected by Landsat 7, Landsat 8, MODIS, and VIIRS observations, both separately and as fused data, to explore the ability of remotely sensed data to capture the subtle variations due to elevation. Daily Nadir BRDF Adjusted Reflectances(NBAR) from MODIS and VIIRS are fused with Landsat imagery to simulate 30m daily data via the Enhanced Spatial and Temporal Adaptive Reflectance Fusion Model(ESTARFM) algorithm. Piecewise logistic functions are fit to the time series to establish spring leaf-out dates. Acadia National Park, a region frequently affected by coastal clouds, is a particularly useful study area as it falls in a Landsat overlap region and thus offers the possibility of acquiring as many as 4 Landsat observations in a 16 day period. With the recent launch of Sentinel 2A, the community will have routine access to such high spatial and temporal data for phenological monitoring.

  10. A spatially-variant deconvolution method based on total variation for optical coherence tomography images

    NASA Astrophysics Data System (ADS)

    Almasganj, Mohammad; Adabi, Saba; Fatemizadeh, Emad; Xu, Qiuyun; Sadeghi, Hamid; Daveluy, Steven; Nasiriavanaki, Mohammadreza

    2017-03-01

    Optical Coherence Tomography (OCT) has a great potential to elicit clinically useful information from tissues due to its high axial and transversal resolution. In practice, an OCT setup cannot reach to its theoretical resolution due to imperfections of its components, which make its images blurry. The blurriness is different alongside regions of image; thus, they cannot be modeled by a unique point spread function (PSF). In this paper, we investigate the use of solid phantoms to estimate the PSF of each sub-region of imaging system. We then utilize Lucy-Richardson, Hybr and total variation (TV) based iterative deconvolution methods for mitigating occurred spatially variant blurriness. It is shown that the TV based method will suppress the so-called speckle noise in OCT images better than the two other approaches. The performance of proposed algorithm is tested on various samples, including several skin tissues besides the test image blurred with synthetic PSF-map, demonstrating qualitatively and quantitatively the advantage of TV based deconvolution method using spatially-variant PSF for enhancing image quality.

  11. Engineered Ferritin for Magnetogenetic Manipulation of Proteins and Organelles Inside Living Cells.

    PubMed

    Liße, Domenik; Monzel, Cornelia; Vicario, Chiara; Manzi, John; Maurin, Isabelle; Coppey, Mathieu; Piehler, Jacob; Dahan, Maxime

    2017-11-01

    Magnetogenetics is emerging as a novel approach for remote-controlled manipulation of cellular functions in tissues and organisms with high spatial and temporal resolution. A critical, still challenging issue for these techniques is to conjugate target proteins with magnetic probes that can satisfy multiple colloidal and biofunctional constraints. Here, semisynthetic magnetic nanoparticles are tailored based on human ferritin coupled to monomeric enhanced green fluorescent protein (mEGFP) for magnetic manipulation of proteins inside living cells. This study demonstrates efficient delivery, intracellular stealth properties, and rapid subcellular targeting of those magnetic nanoparticles via GFP-nanobody interactions. By means of magnetic field gradients, rapid spatial reorganization in the cytosol of proteins captured to the nanoparticle surface is achieved. Moreover, exploiting efficient nanoparticle targeting to intracellular membranes, remote-controlled arrest of mitochondrial dynamics using magnetic fields is demonstrated. The studies establish subcellular control of proteins and organelles with unprecedented spatial and temporal resolution, thus opening new prospects for magnetogenetic applications in fundamental cell biology and nanomedicine. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Effects of spatial resolution

    NASA Technical Reports Server (NTRS)

    Abrams, M.

    1982-01-01

    Studies of the effects of spatial resolution on extraction of geologic information are woefully lacking but spatial resolution effects can be examined as they influence two general categories: detection of spatial features per se; and the effects of IFOV on the definition of spectral signatures and on general mapping abilities.

  13. Myocardial perfusion magnetic resonance imaging using sliding-window conjugate-gradient HYPR methods in canine with stenotic coronary arteries.

    PubMed

    Ge, Lan; Kino, Aya; Lee, Daniel; Dharmakumar, Rohan; Carr, James C; Li, Debiao

    2010-01-01

    First-pass perfusion magnetic resonance imaging (MRI) is a promising technique for detecting ischemic heart disease. However, the diagnostic value of the method is limited by the low spatial coverage, resolution, signal-to-noise ratio (SNR), and cardiac motion-related image artifacts. A combination of sliding window and conjugate-gradient HighlY constrained back-PRojection reconstruction (SW-CG-HYPR) method has been proposed in healthy volunteer studies to reduce the acquisition window for each slice while maintaining the temporal resolution of 1 frame per heartbeat in myocardial perfusion MRI. This method allows for improved spatial coverage, resolution, and SNR. In this study, we use a controlled animal model to test whether the myocardial territory supplied by a stenotic coronary artery can be detected accurately by SW-CG-HYPR perfusion method under pharmacological stress. Results from 6 mongrel dogs (15-25 kg) studies demonstrate the feasibility of SW-CG-HYPR to detect regional perfusion defects. Using this method, the acquisition time per cardiac cycle was reduced by a factor of 4, and the spatial coverage was increased from 2 to 3 slices to 6 slices as compared with the conventional techniques including both turbo-Fast Low Angle Short (FLASH) and echoplanar imaging (EPI). The SNR of the healthy myocardium at peak enhancement with SW-CG-HYPR (12.68 ± 2.46) is significantly higher (P < 0.01) than the turbo-FLASH (8.65 ± 1.93) and EPI (5.48 ± 1.24). The spatial resolution of SW-CG-HYPR images is 1.2 × 1.2 × 8.0 mm, which is better than the turbo-FLASH (1.8 × 1.8 × 8.0 mm) and EPI (2.0 × 1.8 × 8.0 mm). Sliding-window CG-HYPR is a promising technique for myocardial perfusion MRI. This technique provides higher image quality with respect to significantly improved SNR and spatial resolution of the myocardial perfusion images, which might improve myocardial perfusion imaging in a clinical setting.

  14. Results of the spatial resolution simulation for multispectral data (resolution brochures)

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The variable information content of Earth Resource products at different levels of spatial resolution and in different spectral bands is addressed. A low-cost brochure that scientists and laymen could use to visualize the effects of increasing the spatial resolution of multispectral scanner images was produced.

  15. Common path in-line holography using enhanced joint object reference digital interferometers

    PubMed Central

    Kelner, Roy; Katz, Barak; Rosen, Joseph

    2014-01-01

    Joint object reference digital interferometer (JORDI) is a recently developed system capable of recording holograms of various types [Opt. Lett. 38(22), 4719 (2013)24322115]. Presented here is a new enhanced system design that is based on the previous JORDI. While the previous JORDI has been based purely on diffractive optical elements, displayed on spatial light modulators, the present design incorporates an additional refractive objective lens, thus enabling hologram recording with improved resolution and increased system applicability. Experimental results demonstrate successful hologram recording for various types of objects, including transmissive, reflective, three-dimensional, phase and highly scattering objects. The resolution limit of the system is analyzed and experimentally validated. Finally, the suitability of JORDI for microscopic applications is verified as a microscope objective based configuration of the system is demonstrated. PMID:24663838

  16. Combining SMOS with visible and near/shortwave/thermal infrared satellite data for high resolution soil moisture estimates

    NASA Astrophysics Data System (ADS)

    Sánchez-Ruiz, Sergio; Piles, María; Sánchez, Nilda; Martínez-Fernández, José; Vall-llossera, Mercè; Camps, Adriano

    2014-08-01

    Sensors in the range of visible and near-shortwave-thermal infrared regions can be used in combination with passive microwave observations to provide soil moisture maps at much higher spatial resolution than the original resolution of current radiometers. To do so, a new downscaling algorithm ultimately based on the land surface temperature (LST) - Normalized Difference Vegetation Index (NDVI) - Brightness Temperature (TB) relationship is used, in which shortwave infrared indices are used as vegetation descriptors, instead of the more common near infrared ones. The theoretical basis of those indices, calculated as the normalized ratio of the 1240, 1640 and 2130 nm shortwave infrared (SWIR) bands and the 858 nm near infrared (NIR) band indicate that they are able to provide estimates of the vegetation water content. These so-called water indices extracted from MODIS products, have been used together with MODIS LST, and SMOS TB to improve the spatial resolution of ∼40 km SMOS soil moisture estimates. The aim was to retrieve soil moisture maps with the same accuracy as SMOS, but at the same resolution of the MODIS dataset, i.e., 500 m, which were then compared against in situ measurements from the REMEDHUS network in Spain. Results using two years of SMOS and MODIS data showed a similar performance for the four indices, with slightly better results when using the index derived from the first SWIR band. For the areal-average, a coefficient of correlation (R) of ∼0.61 and ∼0.72 for the morning and afternoon orbits, respectively, and a centered root mean square difference (cRMSD) of ∼0.04 m3 m-3 for both orbits was obtained. A twofold improvement of the current versions of this downscaling approach has been achieved by using more frequent and higher spatial resolution water indexes as vegetation descriptors: (1) the spatial resolution of the resulting soil moisture maps can be enhanced from ∼40 km up to 500 m, and (2) more accurate soil moisture maps (in terms of R and cRMSD) can be obtained, especially in periods of high vegetation activity. The results of this study support the use of high resolution LST and SWIR-based vegetation indices to disaggregate SMOS observations down to 500 m soil moisture maps, meeting the needs of fine-scale hydrological applications.

  17. Using Anatomic Magnetic Resonance Image Information to Enhance Visualization and Interpretation of Functional Images: A Comparison of Methods Applied to Clinical Arterial Spin Labeling Images

    PubMed Central

    Dai, Weiying; Soman, Salil; Hackney, David B.; Wong, Eric T.; Robson, Philip M.; Alsop, David C.

    2017-01-01

    Functional imaging provides hemodynamic and metabolic information and is increasingly being incorporated into clinical diagnostic and research studies. Typically functional images have reduced signal-to-noise ratio and spatial resolution compared to other non-functional cross sectional images obtained as part of a routine clinical protocol. We hypothesized that enhancing visualization and interpretation of functional images with anatomic information could provide preferable quality and superior diagnostic value. In this work, we implemented five methods (frequency addition, frequency multiplication, wavelet transform, non-subsampled contourlet transform and intensity-hue-saturation) and a newly proposed ShArpening by Local Similarity with Anatomic images (SALSA) method to enhance the visualization of functional images, while preserving the original functional contrast and quantitative signal intensity characteristics over larger spatial scales. Arterial spin labeling blood flow MR images of the brain were visualization enhanced using anatomic images with multiple contrasts. The algorithms were validated on a numerical phantom and their performance on images of brain tumor patients were assessed by quantitative metrics and neuroradiologist subjective ratings. The frequency multiplication method had the lowest residual error for preserving the original functional image contrast at larger spatial scales (55%–98% of the other methods with simulated data and 64%–86% with experimental data). It was also significantly more highly graded by the radiologists (p<0.005 for clear brain anatomy around the tumor). Compared to other methods, the SALSA provided 11%–133% higher similarity with ground truth images in the simulation and showed just slightly lower neuroradiologist grading score. Most of these monochrome methods do not require any prior knowledge about the functional and anatomic image characteristics, except the acquired resolution. Hence, automatic implementation on clinical images should be readily feasible. PMID:27723582

  18. Enhanced-Resolution Satellite Microwave Brightness Temperature Records for Mapping Boreal-Arctic Landscape Freeze-Thaw Heterogeneity

    NASA Astrophysics Data System (ADS)

    Kim, Y.; Du, J.; Kimball, J. S.

    2017-12-01

    The landscape freeze-thaw (FT) status derived from satellite microwave remote sensing is closely linked to vegetation phenology and productivity, surface energy exchange, evapotranspiration, snow/ice melt dynamics, and trace gas fluxes over land areas affected by seasonally frozen temperatures. A long-term global satellite microwave Earth System Data Record of daily landscape freeze-thaw status (FT-ESDR) was developed using similar calibrated 37GHz, vertically-polarized (V-pol) brightness temperatures (Tb) from SMMR, SSM/I, and SSMIS sensors. The FT-ESDR shows mean annual spatial classification accuracies of 90.3 and 84.3 % for PM and AM overpass retrievals relative surface air temperature (SAT) measurement based FT estimates from global weather stations. However, the coarse FT-ESDR gridding (25-km) is insufficient to distinguish finer scale FT heterogeneity. In this study, we tested alternative finer scale FT estimates derived from two enhanced polar-grid (3.125-km and 6-km resolution), 36.5 GHz V-pol Tb records derived from calibrated AMSR-E and AMSR2 sensor observations. The daily FT estimates are derived using a modified seasonal threshold algorithm that classifies daily Tb variations in relation to grid cell-wise FT thresholds calibrated using ERA-Interim reanalysis based SAT, downscaled using a digital terrain map and estimated temperature lapse rates. The resulting polar-grid FT records for a selected study year (2004) show mean annual spatial classification accuracies of 90.1% (84.2%) and 93.1% (85.8%) for respective PM (AM) 3.125km and 6-km Tb retrievals relative to in situ SAT measurement based FT estimates from regional weather stations. Areas with enhanced FT accuracy include water-land boundaries and mountainous terrain. Differences in FT patterns and relative accuracy obtained from the enhanced grid Tb records were attributed to several factors, including different noise contributions from underlying Tb processing and spatial mismatches between Tb retrievals and SAT calibrated FT thresholds.

  19. IMPROVING THE ACCURACY OF HISTORIC SATELLITE IMAGE CLASSIFICATION BY COMBINING LOW-RESOLUTION MULTISPECTRAL DATA WITH HIGH-RESOLUTION PANCHROMATIC DATA

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Getman, Daniel J

    2008-01-01

    Many attempts to observe changes in terrestrial systems over time would be significantly enhanced if it were possible to improve the accuracy of classifications of low-resolution historic satellite data. In an effort to examine improving the accuracy of historic satellite image classification by combining satellite and air photo data, two experiments were undertaken in which low-resolution multispectral data and high-resolution panchromatic data were combined and then classified using the ECHO spectral-spatial image classification algorithm and the Maximum Likelihood technique. The multispectral data consisted of 6 multispectral channels (30-meter pixel resolution) from Landsat 7. These data were augmented with panchromatic datamore » (15m pixel resolution) from Landsat 7 in the first experiment, and with a mosaic of digital aerial photography (1m pixel resolution) in the second. The addition of the Landsat 7 panchromatic data provided a significant improvement in the accuracy of classifications made using the ECHO algorithm. Although the inclusion of aerial photography provided an improvement in accuracy, this improvement was only statistically significant at a 40-60% level. These results suggest that once error levels associated with combining aerial photography and multispectral satellite data are reduced, this approach has the potential to significantly enhance the precision and accuracy of classifications made using historic remotely sensed data, as a way to extend the time range of efforts to track temporal changes in terrestrial systems.« less

  20. Image sharpening for mixed spatial and spectral resolution satellite systems

    NASA Technical Reports Server (NTRS)

    Hallada, W. A.; Cox, S.

    1983-01-01

    Two methods of image sharpening (reconstruction) are compared. The first, a spatial filtering technique, extrapolates edge information from a high spatial resolution panchromatic band at 10 meters and adds it to the low spatial resolution narrow spectral bands. The second method, a color normalizing technique, is based on the ability to separate image hue and brightness components in spectral data. Using both techniques, multispectral images are sharpened from 30, 50, 70, and 90 meter resolutions. Error rates are calculated for the two methods and all sharpened resolutions. The results indicate that the color normalizing method is superior to the spatial filtering technique.

  1. Spatial Resolution Requirements for Accurate Identification of Drivers of Atrial Fibrillation

    PubMed Central

    Roney, Caroline H.; Cantwell, Chris D.; Bayer, Jason D.; Qureshi, Norman A.; Lim, Phang Boon; Tweedy, Jennifer H.; Kanagaratnam, Prapa; Vigmond, Edward J.; Ng, Fu Siong

    2017-01-01

    Background— Recent studies have demonstrated conflicting mechanisms underlying atrial fibrillation (AF), with the spatial resolution of data often cited as a potential reason for the disagreement. The purpose of this study was to investigate whether the variation in spatial resolution of mapping may lead to misinterpretation of the underlying mechanism in persistent AF. Methods and Results— Simulations of rotors and focal sources were performed to estimate the minimum number of recording points required to correctly identify the underlying AF mechanism. The effects of different data types (action potentials and unipolar or bipolar electrograms) and rotor stability on resolution requirements were investigated. We also determined the ability of clinically used endocardial catheters to identify AF mechanisms using clinically recorded and simulated data. The spatial resolution required for correct identification of rotors and focal sources is a linear function of spatial wavelength (the distance between wavefronts) of the arrhythmia. Rotor localization errors are larger for electrogram data than for action potential data. Stationary rotors are more reliably identified compared with meandering trajectories, for any given spatial resolution. All clinical high-resolution multipolar catheters are of sufficient resolution to accurately detect and track rotors when placed over the rotor core although the low-resolution basket catheter is prone to false detections and may incorrectly identify rotors that are not present. Conclusions— The spatial resolution of AF data can significantly affect the interpretation of the underlying AF mechanism. Therefore, the interpretation of human AF data must be taken in the context of the spatial resolution of the recordings. PMID:28500175

  2. Quantitative characterization of edge enhancement in phase contrast x-ray imaging.

    PubMed

    Monnin, P; Bulling, S; Hoszowska, J; Valley, J F; Meuli, R; Verdun, F R

    2004-06-01

    The aim of this study was to model the edge enhancement effect in in-line holography phase contrast imaging. A simple analytical approach was used to quantify refraction and interference contrasts in terms of beam energy and imaging geometry. The model was applied to predict the peak intensity and frequency of the edge enhancement for images of cylindrical fibers. The calculations were compared with measurements, and the relationship between the spatial resolution of the detector and the amplitude of the phase contrast signal was investigated. Calculations using the analytical model were in good agreement with experimental results for nylon, aluminum and copper wires of 50 to 240 microm diameter, and with numerical simulations based on Fresnel-Kirchhoff theory. A relationship between the defocusing distance and the pixel size of the image detector was established. This analytical model is a useful tool for optimizing imaging parameters in phase contrast in-line holography, including defocusing distance, detector resolution and beam energy.

  3. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kirtley, John R., E-mail: jkirtley@stanford.edu; Rosenberg, Aaron J.; Palmstrom, Johanna C.

    Superconducting QUantum Interference Device (SQUID) microscopy has excellent magnetic field sensitivity, but suffers from modest spatial resolution when compared with other scanning probes. This spatial resolution is determined by both the size of the field sensitive area and the spacing between this area and the sample surface. In this paper we describe scanning SQUID susceptometers that achieve sub-micron spatial resolution while retaining a white noise floor flux sensitivity of ≈2μΦ{sub 0}/Hz{sup 1/2}. This high spatial resolution is accomplished by deep sub-micron feature sizes, well shielded pickup loops fabricated using a planarized process, and a deep etch step that minimizes themore » spacing between the sample surface and the SQUID pickup loop. We describe the design, modeling, fabrication, and testing of these sensors. Although sub-micron spatial resolution has been achieved previously in scanning SQUID sensors, our sensors not only achieve high spatial resolution but also have integrated modulation coils for flux feedback, integrated field coils for susceptibility measurements, and batch processing. They are therefore a generally applicable tool for imaging sample magnetization, currents, and susceptibilities with higher spatial resolution than previous susceptometers.« less

  4. Chromatic and Achromatic Spatial Resolution of Local Field Potentials in Awake Cortex

    PubMed Central

    Jansen, Michael; Li, Xiaobing; Lashgari, Reza; Kremkow, Jens; Bereshpolova, Yulia; Swadlow, Harvey A.; Zaidi, Qasim; Alonso, Jose-Manuel

    2015-01-01

    Local field potentials (LFPs) have become an important measure of neuronal population activity in the brain and could provide robust signals to guide the implant of visual cortical prosthesis in the future. However, it remains unclear whether LFPs can detect weak cortical responses (e.g., cortical responses to equiluminant color) and whether they have enough visual spatial resolution to distinguish different chromatic and achromatic stimulus patterns. By recording from awake behaving macaques in primary visual cortex, here we demonstrate that LFPs respond robustly to pure chromatic stimuli and exhibit ∼2.5 times lower spatial resolution for chromatic than achromatic stimulus patterns, a value that resembles the ratio of achromatic/chromatic resolution measured with psychophysical experiments in humans. We also show that, although the spatial resolution of LFP decays with visual eccentricity as is also the case for single neurons, LFPs have higher spatial resolution and show weaker response suppression to low spatial frequencies than spiking multiunit activity. These results indicate that LFP recordings are an excellent approach to measure spatial resolution from local populations of neurons in visual cortex including those responsive to color. PMID:25416722

  5. Calculation of the spatial resolution in two-photon absorption spectroscopy applied to plasma diagnosis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Garcia-Lechuga, M.; Laser Processing Group, Instituto de Óptica “Daza de Valdés,” CSIC, 28006-Madrid; Fuentes, L. M.

    2014-10-07

    We report a detailed characterization of the spatial resolution provided by two-photon absorption spectroscopy suited for plasma diagnosis via the 1S-2S transition of atomic hydrogen for optogalvanic detection and laser induced fluorescence (LIF). A precise knowledge of the spatial resolution is crucial for a correct interpretation of measurements, if the plasma parameters to be analysed undergo strong spatial variations. The present study is based on a novel approach which provides a reliable and realistic determination of the spatial resolution. Measured irradiance distribution of laser beam waists in the overlap volume, provided by a high resolution UV camera, are employed tomore » resolve coupled rate equations accounting for two-photon excitation, fluorescence decay and ionization. The resulting three-dimensional yield distributions reveal in detail the spatial resolution for optogalvanic and LIF detection and related saturation due to depletion. Two-photon absorption profiles broader than the Fourier transform-limited laser bandwidth are also incorporated in the calculations. The approach allows an accurate analysis of the spatial resolution present in recent and future measurements.« less

  6. 3.0 Tesla high spatial resolution contrast-enhanced magnetic resonance angiography (CE-MRA) of the pulmonary circulation: initial experience with a 32-channel phased array coil using a high relaxivity contrast agent.

    PubMed

    Nael, Kambiz; Fenchel, Michael; Krishnam, Mayil; Finn, J Paul; Laub, Gerhard; Ruehm, Stefan G

    2007-06-01

    To evaluate the technical feasibility of high spatial resolution contrast-enhanced magnetic resonance angiography (CE-MRA) with highly accelerated parallel acquisition at 3.0 T using a 32-channel phased array coil, and a high relaxivity contrast agent. Ten adult healthy volunteers (5 men, 5 women, aged 21-66 years) underwent high spatial resolution CE-MRA of the pulmonary circulation. Imaging was performed at 3 T using a 32-channel phase array coil. After intravenous injection of 1 mL of gadobenate dimeglumine (Gd-BOPTA) at 1.5 mL/s, a timing bolus was used to measure the transit time from the arm vein to the main pulmonary artery. Subsequently following intravenous injection of 0.1 mmol/kg of Gd-BOPTA at the same rate, isotropic high spatial resolution data sets (1 x 1 x 1 mm3) CE-MRA of the entire pulmonary circulation were acquired using a fast gradient-recalled echo sequence (TR/TE 3/1.2 milliseconds, FA 18 degrees) and highly accelerated parallel acquisition (GRAPPA x 6) during a 20-second breath hold. The presence of artifact, noise, and image quality of the pulmonary arterial segments were evaluated independently by 2 radiologists. Phantom measurements were performed to assess the signal-to-noise ratio (SNR). Statistical analysis of data was performed by using Wilcoxon rank sum test and 2-sample Student t test. The interobserver variability was tested by kappa coefficient. All studies were of diagnostic quality as determined by both observers. The pulmonary arteries were routinely identified up to fifth-order branches, with definition in the diagnostic range and excellent interobserver agreement (kappa = 0.84, 95% confidence interval 0.77-0.90). Phantom measurements showed significantly lower SNR (P < 0.01) using GRAPPA (17.3 +/- 18.8) compared with measurements without parallel acquisition (58 +/- 49.4). The described 3 T CE-MRA protocol in addition to high T1 relaxivity of Gd-BOPTA provides sufficient SNR to support highly accelerated parallel acquisition (GRAPPA x 6), resulting in acquisition of isotopic (1 x 1 x 1 mm3) voxels over the entire pulmonary circulation in 20 seconds.

  7. Enhancing GIS Capabilities for High Resolution Earth Science Grids

    NASA Astrophysics Data System (ADS)

    Koziol, B. W.; Oehmke, R.; Li, P.; O'Kuinghttons, R.; Theurich, G.; DeLuca, C.

    2017-12-01

    Applications for high performance GIS will continue to increase as Earth system models pursue more realistic representations of Earth system processes. Finer spatial resolution model input and output, unstructured or irregular modeling grids, data assimilation, and regional coordinate systems present novel challenges for GIS frameworks operating in the Earth system modeling domain. This presentation provides an overview of two GIS-driven applications that combine high performance software with big geospatial datasets to produce value-added tools for the modeling and geoscientific community. First, a large-scale interpolation experiment using National Hydrography Dataset (NHD) catchments, a high resolution rectilinear CONUS grid, and the Earth System Modeling Framework's (ESMF) conservative interpolation capability will be described. ESMF is a parallel, high-performance software toolkit that provides capabilities (e.g. interpolation) for building and coupling Earth science applications. ESMF is developed primarily by the NOAA Environmental Software Infrastructure and Interoperability (NESII) group. The purpose of this experiment was to test and demonstrate the utility of high performance scientific software in traditional GIS domains. Special attention will be paid to the nuanced requirements for dealing with high resolution, unstructured grids in scientific data formats. Second, a chunked interpolation application using ESMF and OpenClimateGIS (OCGIS) will demonstrate how spatial subsetting can virtually remove computing resource ceilings for very high spatial resolution interpolation operations. OCGIS is a NESII-developed Python software package designed for the geospatial manipulation of high-dimensional scientific datasets. An overview of the data processing workflow, why a chunked approach is required, and how the application could be adapted to meet operational requirements will be discussed here. In addition, we'll provide a general overview of OCGIS's parallel subsetting capabilities including challenges in the design and implementation of a scientific data subsetter.

  8. Tracking the ultrafast motion of a single molecule by femtosecond orbital imaging

    NASA Astrophysics Data System (ADS)

    Cocker, Tyler L.; Peller, Dominik; Yu, Ping; Repp, Jascha; Huber, Rupert

    2016-11-01

    Watching a single molecule move on its intrinsic timescale has been one of the central goals of modern nanoscience, and calls for measurements that combine ultrafast temporal resolution with atomic spatial resolution. Steady-state experiments access the requisite spatial scales, as illustrated by direct imaging of individual molecular orbitals using scanning tunnelling microscopy or the acquisition of tip-enhanced Raman and luminescence spectra with sub-molecular resolution. But tracking the intrinsic dynamics of a single molecule directly in the time domain faces the challenge that interactions with the molecule must be confined to a femtosecond time window. For individual nanoparticles, such ultrafast temporal confinement has been demonstrated by combining scanning tunnelling microscopy with so-called lightwave electronics, which uses the oscillating carrier wave of tailored light pulses to directly manipulate electronic motion on timescales faster even than a single cycle of light. Here we build on ultrafast terahertz scanning tunnelling microscopy to access a state-selective tunnelling regime, where the peak of a terahertz electric-field waveform transiently opens an otherwise forbidden tunnelling channel through a single molecular state. It thereby removes a single electron from an individual pentacene molecule’s highest occupied molecular orbital within a time window shorter than one oscillation cycle of the terahertz wave. We exploit this effect to record approximately 100-femtosecond snapshot images of the orbital structure with sub-ångström spatial resolution, and to reveal, through pump/probe measurements, coherent molecular vibrations at terahertz frequencies directly in the time domain. We anticipate that the combination of lightwave electronics and the atomic resolution of our approach will open the door to visualizing ultrafast photochemistry and the operation of molecular electronics on the single-orbital scale.

  9. High-resolution, time-resolved MRA provides superior definition of lower-extremity arterial segments compared to 2D time-of-flight imaging.

    PubMed

    Thornton, F J; Du, J; Suleiman, S A; Dieter, R; Tefera, G; Pillai, K R; Korosec, F R; Mistretta, C A; Grist, T M

    2006-08-01

    To evaluate a novel time-resolved contrast-enhanced (CE) projection reconstruction (PR) magnetic resonance angiography (MRA) method for identifying potential bypass graft target vessels in patients with Class II-IV peripheral vascular disease. Twenty patients (M:F = 15:5, mean age = 58 years, range = 48-83 years), were recruited from routine MRA referrals. All imaging was performed on a 1.5 T MRI system with fast gradients (Signa LX; GE Healthcare, Waukesha, WI). Images were acquired with a novel technique that combined undersampled PR with a time-resolved acquisition to yield an MRA method with high temporal and spatial resolution. The method is called PR hyper time-resolved imaging of contrast kinetics (PR-hyperTRICKS). Quantitative and qualitative analyses were used to compare two-dimensional (2D) time-of-flight (TOF) and PR-hyperTRICKS in 13 arterial segments per lower extremity. Statistical analysis was performed with the Wilcoxon signed-rank test. Fifteen percent (77/517) of the vessels were scored as missing or nondiagnostic with 2D TOF, but were scored as diagnostic with PR-hyperTRICKS. Image quality was superior with PR-hyperTRICKS vs. 2D TOF (on a four-point scale, mean rank = 3.3 +/- 1.2 vs. 2.9 +/- 1.2, P < 0.0001). PR-hyperTRICKS produced images with high contrast-to-noise ratios (CNR) and high spatial and temporal resolution. 2D TOF images were of inferior quality due to moderate spatial resolution, inferior CNR, greater flow-related artifacts, and absence of temporal resolution. PR-hyperTRICKS provides superior preoperative assessment of lower limb ischemia compared to 2D TOF.

  10. [An effective method for improving the imaging spatial resolution of terahertz time domain spectroscopy system].

    PubMed

    Zhang, Zeng-yan; Ji, Te; Zhu, Zhi-yong; Zhao, Hong-wei; Chen, Min; Xiao, Ti-qiao; Guo, Zhi

    2015-01-01

    Terahertz radiation is an electromagnetic radiation in the range between millimeter waves and far infrared. Due to its low energy and non-ionizing characters, THz pulse imaging emerges as a novel tool in many fields, such as material, chemical, biological medicine, and food safety. Limited spatial resolution is a significant restricting factor of terahertz imaging technology. Near field imaging method was proposed to improve the spatial resolution of terahertz system. Submillimeter scale's spauial resolution can be achieved if the income source size is smaller than the wawelength of the incoming source and the source is very close to the sample. But many changes were needed to the traditional terahertz time domain spectroscopy system, and it's very complex to analyze sample's physical parameters through the terahertz signal. A method of inserting a pinhole upstream to the sample was first proposed in this article to improve the spatial resolution of traditional terahertz time domain spectroscopy system. The measured spatial resolution of terahertz time domain spectroscopy system by knife edge method can achieve spatial resolution curves. The moving stage distance between 10 % and 90 Yo of the maximum signals respectively was defined as the, spatial resolution of the system. Imaging spatial resolution of traditional terahertz time domain spectroscopy system was improved dramatically after inserted a pinhole with diameter 0. 5 mm, 2 mm upstream to the sample. Experimental results show that the spatial resolution has been improved from 1. 276 mm to 0. 774 mm, with the increment about 39 %. Though this simple method, the spatial resolution of traditional terahertz time domain spectroscopy system was increased from millimeter scale to submillimeter scale. A pinhole with diameter 1 mm on a polyethylene plate was taken as sample, to terahertz imaging study. The traditional terahertz time domain spectroscopy system and pinhole inserted terahertz time domain spectroscopy system were applied in the imaging experiment respectively. The relative THz-power loss imaging of samples were use in this article. This method generally delivers the best signal to noise ratio in loss images, dispersion effects are cancelled. Terahertz imaging results show that the sample's boundary was more distinct after inserting the pinhole in front of, sample. The results also conform that inserting pinhole in front of sample can improve the imaging spatial resolution effectively. The theoretical analyses of the method which improve the spatial resolution by inserting a pinhole in front of sample were given in this article. The analyses also indicate that the smaller the pinhole size, the longer spatial coherence length of the system, the better spatial resolution of the system. At the same time the terahertz signal will be reduced accordingly. All the experimental results and theoretical analyses indicate that the method of inserting a pinhole in front of sample can improve the spatial resolution of traditional terahertz time domain spectroscopy system effectively, and it will further expand the application of terahertz imaging technology.

  11. Dynamic Contrast-Enhanced MR Microscopy: Functional Imaging in Preclinical Models of Cancer

    NASA Astrophysics Data System (ADS)

    Subashi, Ergys

    Dynamic contrast-enhanced (DCE) MRI has been widely used as a quantitative imaging method for monitoring tumor response to therapy. The pharmacokinetic parameters derived from this technique have been used in more than 100 phase I trials and investigator led studies. The simultaneous challenges of increasing the temporal and spatial resolution, in a setting where the signal from the much smaller voxel is weaker, have made this MR technique difficult to implement in small-animal imaging.Existing preclinical DCE-MRI protocols acquire a limited number of slices resulting in potentially lost information in the third dimension. Furthermore, drug efficacy studies measuring the effect of an anti-angiogenic treatment, often compare the derived biomarkers on manually selected tumor regions or over the entire volume. These measurements include domains where the interpretation of the biomarkers may be unclear (such as in necrotic areas). This dissertation describes and compares a family of four-dimensional (3D spatial + time), projection acquisition, keyhole-sampling strategies that support high spatial and temporal resolution. An interleaved 3D radial trajectory with a quasi-uniform distribution of points in k-space was used for sampling temporally resolved datasets. These volumes were reconstructed with three different k-space filters encompassing a range of possible keyhole strategies. The effect of k-space filtering on spatial and temporal resolution was studied in phantoms and in vivo. The statistical variation of the DCE-MRI measurement is analyzed by considering the fundamental sources of error in the MR signal intensity acquired with the spoiled gradient-echo (SPGR) pulse sequence. Finally, the technique was applied for measuring the extent of the opening of the blood-brain barrier in a mouse model of pediatric glioma and for identifying regions of therapeutic effect in a model of colorectal adenocarcinoma. It is shown that 4D radial keyhole imaging does not degrade the system spatial and temporal resolution at a cost of 20-40% decrease in SNR. The time-dependent concentration of the contrast agent measured in vivo is within the theoretically predicted limits. The uncertainty in measuring the pharmacokinetic parameters with the sequences is of the same order, but always higher than, the uncertainty in measuring the pre-injection longitudinal relaxation time. The histogram of the time-to-peak provides useful knowledge about the spatial distribution of Ktrans and microvascular density. Two regions with distinct kinetic parameters were identified when the TTP map from DCE-MRM was thresholded at 1000 sec. The effect of bevacizumab, as measured by a decrease in Ktrans, was confined to one of these regions. DCE-MRI studies may contribute unique insights into the response of the tumor microenvironment to therapy.

  12. High Temporal and Spatial Resolution Coverage of Earth from Commercial AVSTAR Systems in Geostationary Orbit

    NASA Astrophysics Data System (ADS)

    Lecompte, M. A.; Heaps, J. F.; Williams, F. H.

    Imaging the earth from Geostationary Earth Orbit (GEO) allows frequent updates of environmental conditions within an observable hemisphere at time and spatial scales appropriate to the most transient observable terrestrial phenomena. Coverage provided by current GEO Meteorological Satellites (METSATS) fails to fully exploit this advantage due primarily to obsolescent technology and also institutional inertia. With the full benefit of GEO based imaging unrealized, rapidly evolving phenomena, occurring at the smallest spatial and temporal scales that frequently have significant environmental impact remain unobserved. These phenomena may be precursors for the most destructive natural processes that adversely effect society. Timely distribution of information derived from "real-time" observations thus may provide opportunities to mitigate much of the damage to life and property that would otherwise occur. AstroVision International's AVStar Earth monitoring system is designed to overcome the current limitations if GEO Earth coverage and to provide real time monitoring of changes to the Earth's complete atmospheric, land and marine surface environments including fires, volcanic events, lightning and meteoritic events on a "live," true color, and multispectral basis. The understanding of severe storm dynamics and its coupling to the earth's electro-sphere will be greatly enhanced by observations at unprecedented sampling frequencies and spatial resolution. Better understanding of these natural phenomena and AVStar operational real-time coverage may also benefit society through improvements in severe weather prediction and warning. AstroVision's AVStar system, designed to provide this capability with the first of a constellation of GEO- based commercial environmental monitoring satellites to be launched in late 2003 will be discussed, including spatial and temporal resolution, spectral coverage with applications and an inventory of the potential benefits to society, science, commerce and education.

  13. Comparison of Topographic Effects between the Enhanced Vegetation Index (EVI) and Normalized Difference Vegetation Index (NDVI)

    NASA Astrophysics Data System (ADS)

    Matsushita, B.; Yang, W.; Chen, J.; Onda, Y.

    2007-12-01

    Vegetation indices play an important role in monitoring variations in vegetation. The Enhanced Vegetation Index (EVI) proposed by the MODIS Land Discipline Group and the Normalized Difference Vegetation Index (NDVI) are both global-based vegetation indices aimed at providing consistent spatial and temporal information regarding global vegetation. However, many environmental factors such as atmospheric conditions and soil background may produce errors in these indices. The topographic effect is another very important factor, especially when the indices are used in areas of rough terrain. In this paper, we analyzed differences in the topographic effect between the EVI and the NDVI based on a non-Lambertian model and using two airborne-based images with a spatial resolution of 1.5m acquired from a mountainous area covered by a homogeneous Japanese cypress plantation. The results indicate that the soil adjustment factor "L" in the EVI makes it more sensitive to topographic conditions than is the NDVI. Based on these results, we strongly recommend that the topographic effect be removed from the EVI--as well as from other vegetation indices that similarly include a term without a band ratio format (e.g., the PVI and SAVI)--when these indices are used in conjunction with a high spatial resolution image of an area of rough terrain, where the topographic effect on the vegetarian indices having only a band ratio format (e.g., the NDVI) can usually be ignored.

  14. Optimization of a lensless digital holographic otoscope system for transient measurements of the human tympanic membrane

    PubMed Central

    Dobrev, I.; Furlong, C.; Cheng, J. T.; Rosowski, J. J.

    2014-01-01

    In this paper, we propose a multi-pulsed double exposure (MPDE) acquisition method to quantify in full-field-of-view the transient (i.e., >10 kHz) acoustically induced nanometer scale displacements of the human tympanic membrane (TM or eardrum). The method takes advantage of the geometrical linearity and repeatability of the TM displacements to enable high-speed measurements with a conventional camera (i.e., <20 fps). The MPDE is implemented on a previously developed digital holographic system (DHS) to enhance its measurement capabilities, at a minimum cost, while avoiding constraints imposed by the spatial resolutions and dimensions of high-speed (i.e., >50 kfps) cameras. To our knowledge, there is currently no existing system to provide such capabilities for the study of the human TM. The combination of high temporal (i.e., >50 kHz) and spatial (i.e., >500k data points) resolutions enables measurements of the temporal and frequency response of all points across the surface of the TM simultaneously. The repeatability and accuracy of the MPDE method are verified against a Laser Doppler Vibrometer (LDV) on both artificial membranes and ex-vivo human TMs that are acoustically excited with a sharp (i.e., <100 μs duration) click. The measuring capabilities of the DHS, enhanced by the MPDE acquisition method, allow for quantification of spatially dependent motion parameters of the TM, such as modal frequencies, time constants, as well as inferring local material properties. PMID:25780271

  15. Plasmonics and metamaterials based super-resolution imaging (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Liu, Zhaowei

    2017-05-01

    In recent years, surface imaging of various biological dynamics and biomechanical phenomena has seen a surge of interest. Imaging of processes such as exocytosis and kinesin motion are most effective when depth is limited to a very thin region of interest at the edge of the cell or specimen. However, many objects and processes of interest are of size scales below the diffraction limit for safe, visible wavelength illumination. Super-resolution imaging methods such as structured illumination microscopy and others have offered various compromises between resolution, imaging speed, and bio-compatibility. In this talk, I will present our most recent progress in plasmonic structured illumination microscopy (PSIM) and localized plasmonic structured illumination microscopy (LPSIM), and their applications in bio-imaging. We have achieved wide-field surface imaging with resolution down to 75 nm while maintaining reasonable speed and compatibility with biological specimens. These plasmonic enhanced super resolution techniques offer unique solutions to obtain 50nm spatial resolution and 50 frames per second wide imaging speed at the same time.

  16. Assessment of craniospinal arteriovenous malformations at 3T with highly temporally and highly spatially resolved contrast-enhanced MR angiography.

    PubMed

    Saleh, R S; Lohan, D G; Villablanca, J P; Duckwiler, G; Kee, S T; Finn, J P

    2008-05-01

    Patients with arteriovenous malformation (AVM) are known to have an elevated risk of complications with conventional catheter angiography (CCA) but nonetheless require monitoring of hemodynamics. Thus, we aimed to evaluate both anatomy and hemodynamics in patients with AVM noninvasively by using contrast-enhanced MR angiography (CE-MRA) at 3T and to compare the results with CCA. Institutional review board approval and informed consent were obtained for this Health Insurance Portability and Accountability Act-compliant study. Twenty control subjects without vascular malformation (6 men, 18-70 years of age) and 10 patients with AVMs (6 men, 20-74 years of age) underwent supra-aortic time-resolved and high-spatial-resolution CE-MRA at 3T. Large-field-of-view coronal acquisitions extending from the root of the aorta to the cranial vertex were obtained for both MRA techniques. Image quality was assessed by 2 specialized radiologists by using a 4-point scale. AVM characteristics and nidus size were evaluated by using both CE-MRA and CCA in all patients. In patients, 96.6% (319/330) of arterial segments on high-spatial-resolution MRA and 87.7% (272/310) of arterial segments on time-resolved MRA were graded excellent/good. MRA showed 100% specificity for detecting feeding arteries and venous drainage (n = 8) and complete obliteration of the AVM in 2 cases (concordance with CCA). Nidus diameters measured by both MRA and CCA resulted in a very strong correlation (r = 0.99) with a mild overestimation by MRA (0.10 cm by using the Bland-Altman plot). By combining highly temporally resolved and highly spatially resolved MRA at 3T as complementary studies, one can assess vascular anatomy and hemodynamics noninvasively in patients with AVM.

  17. A scrutiny of heterogeneity at the TCE Source Area BioREmediation (SABRE) test site

    NASA Astrophysics Data System (ADS)

    Rivett, M.; Wealthall, G. P.; Mcmillan, L. A.; Zeeb, P.

    2015-12-01

    A scrutiny of heterogeneity at the UK's Source Area BioREmediation (SABRE) test site is presented to better understand how spatial heterogeneity in subsurface properties and process occurrence may constrain performance of enhanced in-situ bioremediation (EISB). The industrial site contained a 25 to 45 year old trichloroethene (TCE) dense non-aqueous phase liquid (DNAPL) that was exceptionally well monitored via a network of multilevel samplers and high resolution core sampling. Moreover, monitoring was conducted within a 3-sided sheet-pile cell that allowed a controlled streamtube of flow to be drawn through the source zone by an extraction well. We primarily focus on the longitudinal transect of monitoring along the length of the cell that provides a 200 groundwater point sample slice along the streamtube of flow through the DNAPL source zone. TCE dechlorination is shown to be significant throughout the cell domain, but spatially heterogeneous in occurrence and progress of dechlorination to lesser chlorinated ethenes - it is this heterogeneity in dechlorination that we primarily scrutinise. We illustrate the diagnostic use of the relative occurrence of TCE parent and daughter compounds to confirm: dechlorination in close proximity to DNAPL and enhanced during the bioremediation; persistent layers of DNAPL into which gradients of dechlorination products are evident; fast flowpaths through the source zone where dechlorination is less evident; and, the importance of underpinning flow regime understanding on EISB performance. Still, even with such spatial detail, there remains uncertainty over the dataset interpretation. These includes poor closure of mass balance along the cell length for the multilevel sampler based monitoring and points to needs to still understand lateral flows (even in the constrained cell), even greater spatial resolution of point monitoring and potentially, not easily proven, ethene degradation loss.

  18. Additional studies of forest classification accuracy as influenced by multispectral scanner spatial resolution

    NASA Technical Reports Server (NTRS)

    Sadowski, F. E.; Sarno, J. E.

    1976-01-01

    First, an analysis of forest feature signatures was used to help explain the large variation in classification accuracy that can occur among individual forest features for any one case of spatial resolution and the inconsistent changes in classification accuracy that were demonstrated among features as spatial resolution was degraded. Second, the classification rejection threshold was varied in an effort to reduce the large proportion of unclassified resolution elements that previously appeared in the processing of coarse resolution data when a constant rejection threshold was used for all cases of spatial resolution. For the signature analysis, two-channel ellipse plots showing the feature signature distributions for several cases of spatial resolution indicated that the capability of signatures to correctly identify their respective features is dependent on the amount of statistical overlap among signatures. Reductions in signature variance that occur in data of degraded spatial resolution may not necessarily decrease the amount of statistical overlap among signatures having large variance and small mean separations. Features classified by such signatures may thus continue to have similar amounts of misclassified elements in coarser resolution data, and thus, not necessarily improve in classification accuracy.

  19. Handling Different Spatial Resolutions in Image Fusion by Multivariate Curve Resolution-Alternating Least Squares for Incomplete Image Multisets.

    PubMed

    Piqueras, Sara; Bedia, Carmen; Beleites, Claudia; Krafft, Christoph; Popp, Jürgen; Maeder, Marcel; Tauler, Romà; de Juan, Anna

    2018-06-05

    Data fusion of different imaging techniques allows a comprehensive description of chemical and biological systems. Yet, joining images acquired with different spectroscopic platforms is complex because of the different sample orientation and image spatial resolution. Whereas matching sample orientation is often solved by performing suitable affine transformations of rotation, translation, and scaling among images, the main difficulty in image fusion is preserving the spatial detail of the highest spatial resolution image during multitechnique image analysis. In this work, a special variant of the unmixing algorithm Multivariate Curve Resolution Alternating Least Squares (MCR-ALS) for incomplete multisets is proposed to provide a solution for this kind of problem. This algorithm allows analyzing simultaneously images collected with different spectroscopic platforms without losing spatial resolution and ensuring spatial coherence among the images treated. The incomplete multiset structure concatenates images of the two platforms at the lowest spatial resolution with the image acquired with the highest spatial resolution. As a result, the constituents of the sample analyzed are defined by a single set of distribution maps, common to all platforms used and with the highest spatial resolution, and their related extended spectral signatures, covering the signals provided by each of the fused techniques. We demonstrate the potential of the new variant of MCR-ALS for multitechnique analysis on three case studies: (i) a model example of MIR and Raman images of pharmaceutical mixture, (ii) FT-IR and Raman images of palatine tonsil tissue, and (iii) mass spectrometry and Raman images of bean tissue.

  20. Tip-Enhanced Raman Scattering Microscopy: A Step toward Nanoscale Control of Intrinsic Molecular Properties

    NASA Astrophysics Data System (ADS)

    Yano, Taka-aki; Hara, Masahiko

    2018-06-01

    Tip-enhanced Raman scattering microscopy, a family of scanning probe microscopy techniques, has been recognized as a powerful surface analytical technique with both single-molecule sensitivity and angstrom-scale spatial resolution. This review covers the current status of tip-enhanced Raman scattering microscopy in surface and material nanosciences, including a brief history, the basic principles, and applications for the nanoscale characterization of a variety of nanomaterials. The focus is on the recent trend of combining tip-enhanced Raman scattering microscopy with various external stimuli such as pressure, voltage, light, and temperature, which enables the local control of the molecular properties and functions and also enables chemical reactions to be induced on a nanometer scale.

  1. Assessing the Resolution Adaptability of the Zhang-McFarlane Cumulus Parameterization With Spatial and Temporal Averaging: RESOLUTION ADAPTABILITY OF ZM SCHEME

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yun, Yuxing; Fan, Jiwen; Xiao, Heng

    Realistic modeling of cumulus convection at fine model resolutions (a few to a few tens of km) is problematic since it requires the cumulus scheme to adapt to higher resolution than they were originally designed for (~100 km). To solve this problem, we implement the spatial averaging method proposed in Xiao et al. (2015) and also propose a temporal averaging method for the large-scale convective available potential energy (CAPE) tendency in the Zhang-McFarlane (ZM) cumulus parameterization. The resolution adaptability of the original ZM scheme, the scheme with spatial averaging, and the scheme with both spatial and temporal averaging at 4-32more » km resolution is assessed using the Weather Research and Forecasting (WRF) model, by comparing with Cloud Resolving Model (CRM) results. We find that the original ZM scheme has very poor resolution adaptability, with sub-grid convective transport and precipitation increasing significantly as the resolution increases. The spatial averaging method improves the resolution adaptability of the ZM scheme and better conserves the total transport of moist static energy and total precipitation. With the temporal averaging method, the resolution adaptability of the scheme is further improved, with sub-grid convective precipitation becoming smaller than resolved precipitation for resolution higher than 8 km, which is consistent with the results from the CRM simulation. Both the spatial distribution and time series of precipitation are improved with the spatial and temporal averaging methods. The results may be helpful for developing resolution adaptability for other cumulus parameterizations that are based on quasi-equilibrium assumption.« less

  2. Achieving high spatial resolution using a microchannel plate detector with an economic and scalable approach

    NASA Astrophysics Data System (ADS)

    Wiggins, B. B.; deSouza, Z. O.; Vadas, J.; Alexander, A.; Hudan, S.; deSouza, R. T.

    2017-11-01

    A second generation position-sensitive microchannel plate detector using the induced signal approach has been realized. This detector is presently capable of measuring the incident position of electrons, photons, or ions. To assess the spatial resolution, the masked detector was illuminated by electrons. The initial, measured spatial resolution of 276 μm FWHM was improved by requiring a minimum signal amplitude on the anode and by employing digital signal processing techniques. The resulting measured spatial resolution of 119 μm FWHM corresponds to an intrinsic resolution of 98 μm FWHM when the effect of the finite slit width is de-convoluted. This measurement is a substantial improvement from the last reported spatial resolution of 466 μm FWHM using the induced signal approach. To understand the factors that limit the measured resolution, the performance of the detector is simulated.

  3. Statistical model based iterative reconstruction (MBIR) in clinical CT systems. Part II. Experimental assessment of spatial resolution performance.

    PubMed

    Li, Ke; Garrett, John; Ge, Yongshuai; Chen, Guang-Hong

    2014-07-01

    Statistical model based iterative reconstruction (MBIR) methods have been introduced to clinical CT systems and are being used in some clinical diagnostic applications. The purpose of this paper is to experimentally assess the unique spatial resolution characteristics of this nonlinear reconstruction method and identify its potential impact on the detectabilities and the associated radiation dose levels for specific imaging tasks. The thoracic section of a pediatric phantom was repeatedly scanned 50 or 100 times using a 64-slice clinical CT scanner at four different dose levels [CTDIvol =4, 8, 12, 16 (mGy)]. Both filtered backprojection (FBP) and MBIR (Veo(®), GE Healthcare, Waukesha, WI) were used for image reconstruction and results were compared with one another. Eight test objects in the phantom with contrast levels ranging from 13 to 1710 HU were used to assess spatial resolution. The axial spatial resolution was quantified with the point spread function (PSF), while the z resolution was quantified with the slice sensitivity profile. Both were measured locally on the test objects and in the image domain. The dependence of spatial resolution on contrast and dose levels was studied. The study also features a systematic investigation of the potential trade-off between spatial resolution and locally defined noise and their joint impact on the overall image quality, which was quantified by the image domain-based channelized Hotelling observer (CHO) detectability index d'. (1) The axial spatial resolution of MBIR depends on both radiation dose level and image contrast level, whereas it is supposedly independent of these two factors in FBP. The axial spatial resolution of MBIR always improved with an increasing radiation dose level and/or contrast level. (2) The axial spatial resolution of MBIR became equivalent to that of FBP at some transitional contrast level, above which MBIR demonstrated superior spatial resolution than FBP (and vice versa); the value of this transitional contrast highly depended on the dose level. (3) The PSFs of MBIR could be approximated as Gaussian functions with reasonably good accuracy. (4) Thez resolution of MBIR showed similar contrast and dose dependence. (5) Noise standard deviation assessed on the edges of objects demonstrated a trade-off with spatial resolution in MBIR. (5) When both spatial resolution and image noise were considered using the CHO analysis, MBIR led to significant improvement in the overall CT image quality for both high and low contrast detection tasks at both standard and low dose levels. Due to the intrinsic nonlinearity of the MBIR method, many well-known CT spatial resolution and noise properties have been modified. In particular, dose dependence and contrast dependence have been introduced to the spatial resolution of CT images by MBIR. The method has also introduced some novel noise-resolution trade-off not seen in traditional CT images. While the benefits of MBIR regarding the overall image quality, as demonstrated in this work, are significant, the optimal use of this method in clinical practice demands a thorough understanding of its unique physical characteristics.

  4. Computational analysis of high resolution unsteady airloads for rotor aeroacoustics

    NASA Technical Reports Server (NTRS)

    Quackenbush, Todd R.; Lam, C.-M. Gordon; Wachspress, Daniel A.; Bliss, Donald B.

    1994-01-01

    The study of helicopter aerodynamic loading for acoustics applications requires the application of efficient yet accurate simulations of the velocity field induced by the rotor's vortex wake. This report summarizes work to date on the development of such an analysis, which builds on the Constant Vorticity Contour (CVC) free wake model, previously implemented for the study of vibratory loading in the RotorCRAFT computer code. The present effort has focused on implementation of an airload reconstruction approach that computes high resolution airload solutions of rotor/rotor-wake interactions required for acoustics computations. Supplementary efforts on the development of improved vortex core modeling, unsteady aerodynamic effects, higher spatial resolution of rotor loading, and fast vortex wake implementations have substantially enhanced the capabilities of the resulting software, denoted RotorCRAFT/AA (AeroAcoustics). Results of validation calculations using recently acquired model rotor data show that by employing airload reconstruction it is possible to apply the CVC wake analysis with temporal and spatial resolution suitable for acoustics applications while reducing the computation time required by one to two orders of magnitude relative to that required by direct calculations. Promising correlation with this body of airload and noise data has been obtained for a variety of rotor configurations and operating conditions.

  5. Synergistic use of MODIS cloud products and AIRS radiance measurements for retrieval of cloud parameters

    NASA Astrophysics Data System (ADS)

    Li, J.; Menzel, W.; Sun, F.; Schmit, T.

    2003-12-01

    The Moderate-Resolution Imaging Spectroradiometer (MODIS) and Atmospheric Infrared Sounder (AIRS) measurements from the Earth Observing System's (EOS) Aqua satellite will enable global monitoring of the distribution of clouds. MODIS is able to provide at high spatial resolution (1 ~ 5km) the cloud mask, surface and cloud types, cloud phase, cloud-top pressure (CTP), effective cloud amount (ECA), cloud particle size (CPS), and cloud water path (CWP). AIRS is able to provide CTP, ECA, CPS, and CWP within the AIRS footprint with much better accuracy using its greatly enhanced hyperspectral remote sensing capability. The combined MODIS / AIRS system offers the opportunity for cloud products improved over those possible from either system alone. The algorithm developed was applied to process the AIRS longwave cloudy radiance measurements; results are compared with MODIS cloud products, as well as with the Geostationary Operational Environmental Satellite (GOES) sounder cloud products, to demonstrate the advantage of synergistic use of high spatial resolution MODIS cloud products and high spectral resolution AIRS sounder radiance measurements for optimal cloud retrieval. Data from ground-based instrumentation at the Atmospheric Radiation Measurement (ARM) Program Cloud and Radiation Test Bed (CART) in Oklahoma were used for the validation; results show that AIRS improves the MODIS cloud products in certain cases such as low-level clouds.

  6. Plasmonic Colloidal Nanoantennas for Tip-Enhanced Raman Spectrocopy

    NASA Astrophysics Data System (ADS)

    Dill, Tyler J.

    Plasmonic nanoantennas that a support localized surface plasmon resonance (LSPR) are capable of confining visible light to subwavelength dimensions due to strong electromagnetic field enhancement at the probe tip. Nanoantenna enable optical methods such as tip-enhanced Raman spectroscopy (TERS), a technique that uses scanning probe microscopy tips to provide chemical information with nanoscale spatial resolution and single-molecule sensitivities. The LSPR supported by the probe tip is extremely sensitive to the nanoscale morphology of the nanoantenna. Control of nanoscale morphology is notoriously difficult to achieve, resulting in TERS probes with poor reproducibility. In my thesis, I demonstrate high-performance, predictable, and broadband nanospectroscopy probes that are fabricated by self-assembly. Shaped metal nanoparticles are organized into dense layers and deposited onto scanning probe tips. When coupled to a metal substrate, these probes support a strong optical resonance in the gap between the substrate and the probe, producing dramatic field enhancements. I show through experiment and electromagnetic modeling that close-packed but electrically isolated nanoparticles are electromagnetically coupled. Hybridized LSPRs supported by self-assembled nanoparticles with a broadband optical response, giving colloidal nanoantenna a high tolerance for geometric variation resulting from fabrication. I find that coupled nanoparticles act as a waveguide, transferring energy from many neighboring nanoparticles towards the active TERS apex. I also use surface-enhanced Raman spectroscopy (SERS) to characterize the effects of nanoparticle polydispersity and gap height on the Raman enhancement. These colloidal probes have consistently achieved dramatic Raman enhancements in the range of 108-109 with sub-50 nm spatial resolution. Furthermore, in contrast to other nanospectroscopy probes, these colloidal probes can be fabricated in a scalable fashion with a batch-to-batch reproducibility of 80%. This body of work serves as an important demonstration that bottom-up engineering can be used for batch fabricatation of high-performance and high-reliability devices using inexpensive equipment and materials.

  7. Sub-pixel flood inundation mapping from multispectral remotely sensed images based on discrete particle swarm optimization

    NASA Astrophysics Data System (ADS)

    Li, Linyi; Chen, Yun; Yu, Xin; Liu, Rui; Huang, Chang

    2015-03-01

    The study of flood inundation is significant to human life and social economy. Remote sensing technology has provided an effective way to study the spatial and temporal characteristics of inundation. Remotely sensed images with high temporal resolutions are widely used in mapping inundation. However, mixed pixels do exist due to their relatively low spatial resolutions. One of the most popular approaches to resolve this issue is sub-pixel mapping. In this paper, a novel discrete particle swarm optimization (DPSO) based sub-pixel flood inundation mapping (DPSO-SFIM) method is proposed to achieve an improved accuracy in mapping inundation at a sub-pixel scale. The evaluation criterion for sub-pixel inundation mapping is formulated. The DPSO-SFIM algorithm is developed, including particle discrete encoding, fitness function designing and swarm search strategy. The accuracy of DPSO-SFIM in mapping inundation at a sub-pixel scale was evaluated using Landsat ETM + images from study areas in Australia and China. The results show that DPSO-SFIM consistently outperformed the four traditional SFIM methods in these study areas. A sensitivity analysis of DPSO-SFIM was also carried out to evaluate its performances. It is hoped that the results of this study will enhance the application of medium-low spatial resolution images in inundation detection and mapping, and thereby support the ecological and environmental studies of river basins.

  8. Effects of electrode size and spacing on sensory modalities in the phantom thumb perception area for the forearm amputees.

    PubMed

    Li, P; Chai, G H; Zhu, K H; Lan, N; Sui, X H

    2015-01-01

    Tactile sensory feedback plays a key role in accomplishing the dexterous manipulation of prosthetic hands for the amputees, and the non-invasive transcutaneous electrical nerve stimulation (TENS) of the phantom finger perception (PFP) area would be an effective way to realize sensory feedback clinically. In order to realize the high-spatial-resolution tactile sensory feedback in the PFP region, we investigated the effects of electrode size and spacing on the tactile sensations for potentially optimizing the surface electrode array configuration. Six forearm-amputated subjects were recruited in the psychophysical studies. With the diameter of the circular electrode increasing from 3 mm to 12 mm, the threshold current intensity was enhanced correspondingly under different sensory modalities. The smaller electrode could potentially lead to high sensation spatial resolution. Whereas, the smaller the electrode, the less the number of sensory modalities. For an Φ-3 mm electrode, it is even hard for the subject to perceive any perception modalities under normal stimulating current. In addition, the two-electrode discrimination distance (TEDD) in the phantom thumb perception area decreased with electrode size decreasing in two directions of parallel or perpendicular to the forearm. No significant difference of TEDD existed along the two directions. Studies in this paper would guide the configuration optimization of the TENS electrode array for potential high spatial-resolution sensory feedback.

  9. Validation of the SimSET simulation package for modeling the Siemens Biograph mCT PET scanner

    NASA Astrophysics Data System (ADS)

    Poon, Jonathan K.; Dahlbom, Magnus L.; Casey, Michael E.; Qi, Jinyi; Cherry, Simon R.; Badawi, Ramsey D.

    2015-02-01

    Monte Carlo simulation provides a valuable tool in performance assessment and optimization of system design parameters for PET scanners. SimSET is a popular Monte Carlo simulation toolkit that features fast simulation time, as well as variance reduction tools to further enhance computational efficiency. However, SimSET has lacked the ability to simulate block detectors until its most recent release. Our goal is to validate new features of SimSET by developing a simulation model of the Siemens Biograph mCT PET scanner and comparing the results to a simulation model developed in the GATE simulation suite and to experimental results. We used the NEMA NU-2 2007 scatter fraction, count rates, and spatial resolution protocols to validate the SimSET simulation model and its new features. The SimSET model overestimated the experimental results of the count rate tests by 11-23% and the spatial resolution test by 13-28%, which is comparable to previous validation studies of other PET scanners in the literature. The difference between the SimSET and GATE simulation was approximately 4-8% for the count rate test and approximately 3-11% for the spatial resolution test. In terms of computational time, SimSET performed simulations approximately 11 times faster than GATE simulations. The new block detector model in SimSET offers a fast and reasonably accurate simulation toolkit for PET imaging applications.

  10. Detecting cm-scale hot spot over 24-km-long single-mode fiber by using differential pulse pair BOTDA based on double-peak spectrum.

    PubMed

    Diakaridia, Sanogo; Pan, Yue; Xu, Pengbai; Zhou, Dengwang; Wang, Benzhang; Teng, Lei; Lu, Zhiwei; Ba, Dexin; Dong, Yongkang

    2017-07-24

    In distributed Brillouin optical fiber sensor when the length of the perturbation to be detected is much smaller than the spatial resolution that is defined by the pulse width, the measured Brillouin gain spectrum (BGS) experiences two or multiple peaks. In this work, we propose and demonstrate a technique using differential pulse pair Brillouin optical time-domain analysis (DPP-BOTDA) based on double-peak BGS to enhance small-scale events detection capability, where two types of single mode fiber (main fiber and secondary fiber) with 116 MHz Brillouin frequency shift (BFS) difference have been used. We have realized detection of a 5-cm hot spot at the far end of 24-km single mode fiber by employing a 50-cm spatial resolution DPP-BOTDA with only 1GS/s sampling rate (corresponding to 10 cm/point). The BFS at the far end of 24-km sensing fiber has been measured with 0.54 MHz standard deviation which corresponds to a 0.5°C temperature accuracy. This technique is simple and cost effective because it is implemented using the similar experimental setup of the standard BOTDA, however, it should be noted that the consecutive small-scale events have to be separated by a minimum length corresponding to the spatial resolution defined by the pulse width difference.

  11. Evaluating MODIS snow products for modelling snowmelt runoff: Case study of the Rio Grande headwaters

    NASA Astrophysics Data System (ADS)

    Steele, Caitriana; Dialesandro, John; James, Darren; Elias, Emile; Rango, Albert; Bleiweiss, Max

    2017-12-01

    Snow-covered area (SCA) is a key variable in the Snowmelt-Runoff Model (SRM) and in other models for simulating discharge from snowmelt. Landsat Thematic Mapper (TM), Enhanced Thematic Mapper (ETM +) or Operational Land Imager (OLI) provide remotely sensed data at an appropriate spatial resolution for mapping SCA in small headwater basins, but the temporal resolution of the data is low and may not always provide sufficient cloud-free dates. The coarser spatial resolution Moderate Resolution Imaging Spectroradiometer (MODIS) offers better temporal resolution and in cloudy years, MODIS data offer the best alternative for mapping snow cover when finer spatial resolution data are unavailable. However, MODIS' coarse spatial resolution (500 m) can obscure fine spatial patterning in snow cover and some MODIS products are not sensitive to end-of-season snow cover. In this study, we aimed to test MODIS snow products for use in simulating snowmelt runoff from smaller headwater basins by a) comparing maps of TM and MODIS-based SCA and b) determining how SRM streamflow simulations are changed by the different estimates of seasonal snow depletion. We compared gridded MODIS snow products (Collection 5 MOD10A1 fractional and binary SCA; SCA derived from Collection 6 MOD10A1 Normalised Difference Snow Index (NDSI) Snow Cover), and the MODIS Snow Covered-Area and Grain size retrieval (MODSCAG) canopy-corrected fractional SCA (SCAMG), with reference SCA maps (SCAREF) generated from binary classification of TM imagery. SCAMG showed strong agreement with SCAREF; excluding true negatives (where both methods agreed no snow was present) the median percent difference between SCAREF and SCAMG ranged between -2.4% and 4.7%. We simulated runoff for each of the four study years using SRM populated with and calibrated for snow depletion curves derived from SCAREF. We then substituted in each of the MODIS-derived depletion curves. With efficiency coefficients ranging between 0.73 and 0.93, SRM simulation results from the SCAMG runs yielded the best results of all the MODIS products and only slightly underestimated discharge volume (between 7 and 11% of measured annual discharge). SRM simulations that used SCA derived from Collection 6 NDSI Snow Cover also yielded promising results, with efficiency coefficients ranging between 0.73 and 0.91. In conclusion, we recommend that when simulating snowmelt runoff from small basins (<4000 km2) with SRM, we recommend that users select either canopy-corrected MODSCAG or create their own site-specific products from the Collection 6 MOD10A1 NDSI.

  12. a Spiral-Based Downscaling Method for Generating 30 M Time Series Image Data

    NASA Astrophysics Data System (ADS)

    Liu, B.; Chen, J.; Xing, H.; Wu, H.; Zhang, J.

    2017-09-01

    The spatial detail and updating frequency of land cover data are important factors influencing land surface dynamic monitoring applications in high spatial resolution scale. However, the fragmentized patches and seasonal variable of some land cover types (e. g. small crop field, wetland) make it labor-intensive and difficult in the generation of land cover data. Utilizing the high spatial resolution multi-temporal image data is a possible solution. Unfortunately, the spatial and temporal resolution of available remote sensing data like Landsat or MODIS datasets can hardly satisfy the minimum mapping unit and frequency of current land cover mapping / updating at the same time. The generation of high resolution time series may be a compromise to cover the shortage in land cover updating process. One of popular way is to downscale multi-temporal MODIS data with other high spatial resolution auxiliary data like Landsat. But the usual manner of downscaling pixel based on a window may lead to the underdetermined problem in heterogeneous area, result in the uncertainty of some high spatial resolution pixels. Therefore, the downscaled multi-temporal data can hardly reach high spatial resolution as Landsat data. A spiral based method was introduced to downscale low spatial and high temporal resolution image data to high spatial and high temporal resolution image data. By the way of searching the similar pixels around the adjacent region based on the spiral, the pixel set was made up in the adjacent region pixel by pixel. The underdetermined problem is prevented to a large extent from solving the linear system when adopting the pixel set constructed. With the help of ordinary least squares, the method inverted the endmember values of linear system. The high spatial resolution image was reconstructed on the basis of high spatial resolution class map and the endmember values band by band. Then, the high spatial resolution time series was formed with these high spatial resolution images image by image. Simulated experiment and remote sensing image downscaling experiment were conducted. In simulated experiment, the 30 meters class map dataset Globeland30 was adopted to investigate the effect on avoid the underdetermined problem in downscaling procedure and a comparison between spiral and window was conducted. Further, the MODIS NDVI and Landsat image data was adopted to generate the 30m time series NDVI in remote sensing image downscaling experiment. Simulated experiment results showed that the proposed method had a robust performance in downscaling pixel in heterogeneous region and indicated that it was superior to the traditional window-based methods. The high resolution time series generated may be a benefit to the mapping and updating of land cover data.

  13. Studies of a Next-Generation Silicon-Photomultiplier-Based Time-of-Flight PET/CT System.

    PubMed

    Hsu, David F C; Ilan, Ezgi; Peterson, William T; Uribe, Jorge; Lubberink, Mark; Levin, Craig S

    2017-09-01

    This article presents system performance studies for the Discovery MI PET/CT system, a new time-of-flight system based on silicon photomultipliers. System performance and clinical imaging were compared between this next-generation system and other commercially available PET/CT and PET/MR systems, as well as between different reconstruction algorithms. Methods: Spatial resolution, sensitivity, noise-equivalent counting rate, scatter fraction, counting rate accuracy, and image quality were characterized with the National Electrical Manufacturers Association NU-2 2012 standards. Energy resolution and coincidence time resolution were measured. Tests were conducted independently on two Discovery MI scanners installed at Stanford University and Uppsala University, and the results were averaged. Back-to-back patient scans were also performed between the Discovery MI, Discovery 690 PET/CT, and SIGNA PET/MR systems. Clinical images were reconstructed using both ordered-subset expectation maximization and Q.Clear (block-sequential regularized expectation maximization with point-spread function modeling) and were examined qualitatively. Results: The averaged full widths at half maximum (FWHMs) of the radial/tangential/axial spatial resolution reconstructed with filtered backprojection at 1, 10, and 20 cm from the system center were, respectively, 4.10/4.19/4.48 mm, 5.47/4.49/6.01 mm, and 7.53/4.90/6.10 mm. The averaged sensitivity was 13.7 cps/kBq at the center of the field of view. The averaged peak noise-equivalent counting rate was 193.4 kcps at 21.9 kBq/mL, with a scatter fraction of 40.6%. The averaged contrast recovery coefficients for the image-quality phantom were 53.7, 64.0, 73.1, 82.7, 86.8, and 90.7 for the 10-, 13-, 17-, 22-, 28-, and 37-mm-diameter spheres, respectively. The average photopeak energy resolution was 9.40% FWHM, and the average coincidence time resolution was 375.4 ps FWHM. Clinical image comparisons between the PET/CT systems demonstrated the high quality of the Discovery MI. Comparisons between the Discovery MI and SIGNA showed a similar spatial resolution and overall imaging performance. Lastly, the results indicated significantly enhanced image quality and contrast-to-noise performance for Q.Clear, compared with ordered-subset expectation maximization. Conclusion: Excellent performance was achieved with the Discovery MI, including 375 ps FWHM coincidence time resolution and sensitivity of 14 cps/kBq. Comparisons between reconstruction algorithms and other multimodal silicon photomultiplier and non-silicon photomultiplier PET detector system designs indicated that performance can be substantially enhanced with this next-generation system. © 2017 by the Society of Nuclear Medicine and Molecular Imaging.

  14. Chromatic and Achromatic Spatial Resolution of Local Field Potentials in Awake Cortex.

    PubMed

    Jansen, Michael; Li, Xiaobing; Lashgari, Reza; Kremkow, Jens; Bereshpolova, Yulia; Swadlow, Harvey A; Zaidi, Qasim; Alonso, Jose-Manuel

    2015-10-01

    Local field potentials (LFPs) have become an important measure of neuronal population activity in the brain and could provide robust signals to guide the implant of visual cortical prosthesis in the future. However, it remains unclear whether LFPs can detect weak cortical responses (e.g., cortical responses to equiluminant color) and whether they have enough visual spatial resolution to distinguish different chromatic and achromatic stimulus patterns. By recording from awake behaving macaques in primary visual cortex, here we demonstrate that LFPs respond robustly to pure chromatic stimuli and exhibit ∼2.5 times lower spatial resolution for chromatic than achromatic stimulus patterns, a value that resembles the ratio of achromatic/chromatic resolution measured with psychophysical experiments in humans. We also show that, although the spatial resolution of LFP decays with visual eccentricity as is also the case for single neurons, LFPs have higher spatial resolution and show weaker response suppression to low spatial frequencies than spiking multiunit activity. These results indicate that LFP recordings are an excellent approach to measure spatial resolution from local populations of neurons in visual cortex including those responsive to color. © The Author 2014. Published by Oxford University Press.

  15. The spatial resolution of silicon-based electron detectors in beta-autoradiography.

    PubMed

    Cabello, Jorge; Wells, Kevin

    2010-03-21

    Thin tissue autoradiography is an imaging modality where ex-vivo tissue sections are placed in direct contact with autoradiographic film. These tissue sections contain a radiolabelled ligand bound to a specific biomolecule under study. This radioligand emits beta - or beta+ particles ionizing silver halide crystals in the film. High spatial resolution autoradiograms are obtained using low energy radioisotopes, such as (3)H where an intrinsic 0.1-1 microm spatial resolution can be achieved. Several digital alternatives have been presented over the past few years to replace conventional film but their spatial resolution has yet to equal film, although silicon-based imaging technologies have demonstrated higher sensitivity compared to conventional film. It will be shown in this work how pixel size is a critical parameter for achieving high spatial resolution for low energy uncollimated beta imaging. In this work we also examine the confounding factors impeding silicon-based technologies with respect to spatial resolution. The study considers charge diffusion in silicon and detector noise, and this is applied to a range of radioisotopes typically used in autoradiography. Finally an optimal detector geometry to obtain the best possible spatial resolution for a specific technology and a specific radioisotope is suggested.

  16. Detection of fresh bruises in apples by structured-illumination reflectance imaging

    NASA Astrophysics Data System (ADS)

    Lu, Yuzhen; Li, Richard; Lu, Renfu

    2016-05-01

    Detection of fresh bruises in apples remains a challenging task due to the absence of visual symptoms and significant chemical alterations of fruit tissues during the initial stage after the fruit have been bruised. This paper reports on a new structured-illumination reflectance imaging (SIRI) technique for enhanced detection of fresh bruises in apples. Using a digital light projector engine, sinusoidally-modulated illumination at the spatial frequencies of 50, 100, 150 and 200 cycles/m was generated. A digital camera was then used to capture the reflectance images from `Gala' and `Jonagold' apples, immediately after they had been subjected to two levels of bruising by impact tests. A conventional three-phase demodulation (TPD) scheme was applied to the acquired images for obtaining the planar (direct component or DC) and amplitude (alternating component or AC) images. Bruises were identified in the amplitude images with varying image contrasts, depending on spatial frequency. The bruise visibility was further enhanced through post-processing of the amplitude images. Furthermore, three spiral phase transform (SPT)-based demodulation methods, using single and two images and two phase-shifted images, were proposed for obtaining AC images. Results showed that the demodulation methods greatly enhanced the contrast and spatial resolution of the AC images, making it feasible to detect the fresh bruises that, otherwise, could not be achieved by conventional imaging technique with planar or uniform illumination. The effectiveness of image enhancement, however, varied with spatial frequency. Both 2-image and 2-phase SPT methods achieved the performance similar to that by conventional TPD. SIRI technique has demonstrated the capability of detecting fresh bruises in apples, and it has the potential as a new imaging modality for enhancing food quality and safety detection.

  17. Lessons Learned from OMI Observations of Point Source SO2 Pollution

    NASA Technical Reports Server (NTRS)

    Krotkov, N.; Fioletov, V.; McLinden, Chris

    2011-01-01

    The Ozone Monitoring Instrument (OMI) on NASA Aura satellite makes global daily measurements of the total column of sulfur dioxide (SO2), a short-lived trace gas produced by fossil fuel combustion, smelting, and volcanoes. Although anthropogenic SO2 signals may not be detectable in a single OMI pixel, it is possible to see the source and determine its exact location by averaging a large number of individual measurements. We describe new techniques for spatial and temporal averaging that have been applied to the OMI SO2 data to determine the spatial distributions or "fingerprints" of SO2 burdens from top 100 pollution sources in North America. The technique requires averaging of several years of OMI daily measurements to observe SO2 pollution from typical anthropogenic sources. We found that the largest point sources of SO2 in the U.S. produce elevated SO2 values over a relatively small area - within 20-30 km radius. Therefore, one needs higher than OMI spatial resolution to monitor typical SO2 sources. TROPOMI instrument on the ESA Sentinel 5 precursor mission will have improved ground resolution (approximately 7 km at nadir), but is limited to once a day measurement. A pointable geostationary UVB spectrometer with variable spatial resolution and flexible sampling frequency could potentially achieve the goal of daily monitoring of SO2 point sources and resolve downwind plumes. This concept of taking the measurements at high frequency to enhance weak signals needs to be demonstrated with a GEOCAPE precursor mission before 2020, which will help formulating GEOCAPE measurement requirements.

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scaduto, DA; Hu, Y-H; Zhao, W

    Purpose: Spatial resolution in digital breast tomosynthesis (DBT) is affected by inherent/binned detector resolution, oblique entry of x-rays, and focal spot size/motion; the limited angular range further limits spatial resolution in the depth-direction. While DBT is being widely adopted clinically, imaging performance metrics and quality control protocols have not been standardized. AAPM Task Group 245 on Tomosynthesis Quality Control has been formed to address this deficiency. Methods: Methods of measuring spatial resolution are evaluated using two prototype quality control phantoms for DBT. Spatial resolution in the detector plane is measured in projection and reconstruction domains using edge-spread function (ESF), point-spreadmore » function (PSF) and modulation transfer function (MTF). Spatial resolution in the depth-direction and effective slice thickness are measured in the reconstruction domain using slice sensitivity profile (SSP) and artifact spread function (ASF). An oversampled PSF in the depth-direction is measured using a 50 µm angulated tungsten wire, from which the MTF is computed. Object-dependent PSF is derived and compared with ASF. Sensitivity of these measurements to phantom positioning, imaging conditions and reconstruction algorithms is evaluated. Results are compared from systems of varying acquisition geometry (9–25 projections over 15–60°). Dependence of measurements on feature size is investigated. Results: Measurements of spatial resolution using PSF and LSF are shown to depend on feature size; depth-direction spatial resolution measurements are shown to similarly depend on feature size for ASF, though deconvolution with an object function removes feature size-dependence. A slanted wire may be used to measure oversampled PSFs, from which MTFs may be computed for both in-plane and depth-direction resolution. Conclusion: Spatial resolution measured using PSF is object-independent with sufficiently small object; MTF is object-independent. Depth-direction spatial resolution may be measured directly using MTF or indirectly using ASF or SSP as surrogate measurements. While MTF is object-independent, it is invalid for nonlinear reconstructions.« less

  19. Spatial and temporal remote sensing data fusion for vegetation monitoring

    USDA-ARS?s Scientific Manuscript database

    The suite of available remote sensing instruments varies widely in terms of sensor characteristics, spatial resolution and acquisition frequency. For example, the Moderate-resolution Imaging Spectroradiometer (MODIS) provides daily global observations at 250m to 1km spatial resolution. While imagery...

  20. Development of a large-area Multigap RPC with adequate spatial resolution for muon tomography

    NASA Astrophysics Data System (ADS)

    Wang, J.; Wang, Y.; Wang, X.; Zeng, M.; Xie, B.; Han, D.; Lyu, P.; Wang, F.; Li, Y.

    2016-11-01

    We study the performance of a large-area 2-D Multigap Resistive Plate Chamber (MRPC) designed for muon tomography with high spatial resolution. An efficiency up to 98% and a spatial resolution of around 270 μ m are obtained in cosmic ray and X-ray tests. The performance of the MRPC is also investigated for two working gases: standard gas and pure Freon. The result shows that the MRPC working in pure Freon can provide higher efficiency and better spatial resolution.

  1. Climatological Downscaling and Evaluation of AGRMET Precipitation Analyses Over the Continental U.S.

    NASA Astrophysics Data System (ADS)

    Garcia, M.; Peters-Lidard, C. D.; Eylander, J. B.; Daly, C.; Tian, Y.; Zeng, J.

    2007-05-01

    The spatially distributed application of a land surface model (LSM) over a region of interest requires the application of similarly distributed precipitation fields that can be derived from various sources, including surface gauge networks, surface-based radar, and orbital platforms. The spatial variability of precipitation influences the spatial organization of soil temperature and moisture states and, consequently, the spatial variability of land- atmosphere fluxes. The accuracy of spatially-distributed precipitation fields can contribute significantly to the uncertainty of model-based hydrological states and fluxes at the land surface. Collaborations between the Air Force Weather Agency (AFWA), NASA, and Oregon State University have led to improvements in the processing of meteorological forcing inputs for the NASA-GSFC Land Information System (LIS; Kumar et al. 2006), a sophisticated framework for LSM operation and model coupling experiments. Efforts at AFWA toward the production of surface hydrometeorological products are currently in transition from the legacy Agricultural Meteorology modeling system (AGRMET) to use of the LIS framework and procedures. Recent enhancements to meteorological input processing for application to land surface models in LIS include the assimilation of climate-based information for the spatial interpolation and downscaling of precipitation fields. Climatological information included in the LIS-based downscaling procedure for North America is provided by a monthly high-resolution PRISM (Daly et al. 1994, 2002; Daly 2006) dataset based on a 30-year analysis period. The combination of these sources and methods attempts to address the strengths and weaknesses of available legacy products, objective interpolation methods, and the PRISM knowledge-based methodology. All of these efforts are oriented on an operational need for timely estimation of spatial precipitation fields at adequate spatial resolution for customer dissemination and near-real-time simulations in regions of interest. This work focuses on value added to the AGRMET precipitation product by the inclusion of high-quality climatological information on a monthly time scale. The AGRMET method uses microwave-based satellite precipitation estimates from various polar-orbiting platforms (NOAA POES and DMSP), infrared-based estimates from geostationary platforms (GOES, METEOSAT, etc.), related cloud analysis products, and surface gauge observations in a complex and hierarchical blending process. Results from processing of the legacy AGRMET precipitation products over the U.S. using LIS-based methods for downscaling, both with and without climatological factors, are evaluated against high-resolution monthly analyses using the PRISM knowledge- based method (Daly et al. 2002). It is demonstrated that the incorporation of climatological information in a downscaling procedure can significantly enhance the accuracy, and potential utility, of AFWA precipitation products for military and civilian customer applications.

  2. Bayesian geostatistical modelling of soil-transmitted helminth survey data in the People's Republic of China.

    PubMed

    Lai, Ying-Si; Zhou, Xiao-Nong; Utzinger, Jürg; Vounatsou, Penelope

    2013-12-18

    Soil-transmitted helminth infections affect tens of millions of individuals in the People's Republic of China (P.R. China). There is a need for high-resolution estimates of at-risk areas and number of people infected to enhance spatial targeting of control interventions. However, such information is not yet available for P.R. China. A geo-referenced database compiling surveys pertaining to soil-transmitted helminthiasis, carried out from 2000 onwards in P.R. China, was established. Bayesian geostatistical models relating the observed survey data with potential climatic, environmental and socioeconomic predictors were developed and used to predict at-risk areas at high spatial resolution. Predictors were extracted from remote sensing and other readily accessible open-source databases. Advanced Bayesian variable selection methods were employed to develop a parsimonious model. Our results indicate that the prevalence of soil-transmitted helminth infections in P.R. China considerably decreased from 2005 onwards. Yet, some 144 million people were estimated to be infected in 2010. High prevalence (>20%) of the roundworm Ascaris lumbricoides infection was predicted for large areas of Guizhou province, the southern part of Hubei and Sichuan provinces, while the northern part and the south-eastern coastal-line areas of P.R. China had low prevalence (<5%). High infection prevalence (>20%) with hookworm was found in Hainan, the eastern part of Sichuan and the southern part of Yunnan provinces. High infection prevalence (>20%) with the whipworm Trichuris trichiura was found in a few small areas of south P.R. China. Very low prevalence (<0.1%) of hookworm and whipworm infections were predicted for the northern parts of P.R. China. We present the first model-based estimates for soil-transmitted helminth infections throughout P.R. China at high spatial resolution. Our prediction maps provide useful information for the spatial targeting of soil-transmitted helminthiasis control interventions and for long-term monitoring and surveillance in the frame of enhanced efforts to control and eliminate the public health burden of these parasitic worm infections.

  3. Bayesian geostatistical modelling of soil-transmitted helminth survey data in the People’s Republic of China

    PubMed Central

    2013-01-01

    Background Soil-transmitted helminth infections affect tens of millions of individuals in the People’s Republic of China (P.R. China). There is a need for high-resolution estimates of at-risk areas and number of people infected to enhance spatial targeting of control interventions. However, such information is not yet available for P.R. China. Methods A geo-referenced database compiling surveys pertaining to soil-transmitted helminthiasis, carried out from 2000 onwards in P.R. China, was established. Bayesian geostatistical models relating the observed survey data with potential climatic, environmental and socioeconomic predictors were developed and used to predict at-risk areas at high spatial resolution. Predictors were extracted from remote sensing and other readily accessible open-source databases. Advanced Bayesian variable selection methods were employed to develop a parsimonious model. Results Our results indicate that the prevalence of soil-transmitted helminth infections in P.R. China considerably decreased from 2005 onwards. Yet, some 144 million people were estimated to be infected in 2010. High prevalence (>20%) of the roundworm Ascaris lumbricoides infection was predicted for large areas of Guizhou province, the southern part of Hubei and Sichuan provinces, while the northern part and the south-eastern coastal-line areas of P.R. China had low prevalence (<5%). High infection prevalence (>20%) with hookworm was found in Hainan, the eastern part of Sichuan and the southern part of Yunnan provinces. High infection prevalence (>20%) with the whipworm Trichuris trichiura was found in a few small areas of south P.R. China. Very low prevalence (<0.1%) of hookworm and whipworm infections were predicted for the northern parts of P.R. China. Conclusions We present the first model-based estimates for soil-transmitted helminth infections throughout P.R. China at high spatial resolution. Our prediction maps provide useful information for the spatial targeting of soil-transmitted helminthiasis control interventions and for long-term monitoring and surveillance in the frame of enhanced efforts to control and eliminate the public health burden of these parasitic worm infections. PMID:24350825

  4. Some effects of finite spatial resolution on skin friction measurements in turbulent boundary layers

    NASA Technical Reports Server (NTRS)

    Westphal, Russell V.

    1988-01-01

    The effects of finite spatial resolution often cause serious errors in measurements in turbulent boundary layers, with particularly large effects for measurements of fluctuating skin friction and velocities within the sublayer. However, classical analyses of finite spatial resolution effects have generally not accounted for the substantial inhomogeneity and anisotropy of near-wall turbulence. The present study has made use of results from recent computational simulations of wall-bounded turbulent flows to examine spatial resolution effects for measurements made at a wall using both single-sensor probes and those employing two sensing volumes in a V shape. Results are presented to show the effects of finite spatial resolution on a variety of quantitites deduced from the skin friction field.

  5. Vital-dye enhanced fluorescence imaging of gastrointestinal mucosa: metaplasia, neoplasia, inflammation

    PubMed Central

    Muldoon, Timothy J; Polydorides, Alexandros D; Maru, Dipen M; Harpaz, Noam; Harris, Michael T; Hofstettor, Wayne; Hiotis, Spiros P; Kim, Sanghyun A; Ky, Alex J; Anandasabapathy, Sharmila; Richards-Kortum, Rebecca

    2012-01-01

    Background Confocal endomicroscopy has revolutionized endoscopy by offering sub-cellular images of gastrointestinal epithelium; however, field-of-view is limited. There is a need for multi-scale endoscopy platforms that use widefield imaging to better direct placement of high-resolution probes. Design Feasibility Study Objective This study evaluates the feasibility of a single agent, proflavine hemisulfate, as a contrast medium during both widefield and high resolution imaging to characterize morphologic changes associated with a variety of gastrointestinal conditions. Setting U.T. M.D. Anderson Cancer Center (Houston, TX) and Mount Sinai Medical Center (New York, NY) Patients, Interventions, and Main Outcome Measurements Surgical specimens were obtained from 15 patients undergoing esophagectomy/colectomy. Proflavine, a vital fluorescent dye, was applied topically. Specimens were imaged with a widefield multispectral microscope and a high-resolution microendoscope. Images were compared to histopathology. Results Widefield-fluorescence imaging enhanced visualization of morphology, including the presence and spatial distribution of glands, glandular distortion, atrophy and crowding. High-resolution imaging of widefield-abnormal areas revealed that neoplastic progression corresponded to glandular heterogeneity and nuclear crowding in dysplasia, with glandular effacement in carcinoma. These widefield and high-resolution image features correlated well with histopathology. Limitations This imaging approach must be validated in vivo with a larger sample size. Conclusions Multi-scale proflavine-enhanced fluorescence imaging can delineate epithelial changes in a variety of gastrointestinal conditions. Distorted glandular features seen with widefield imaging could serve as a critical ‘bridge’ to high-resolution probe placement. An endoscopic platform combining the two modalities with a single vital-dye may facilitate point-of-care decision-making by providing real-time, in vivo diagnoses. PMID:22301343

  6. Vital-dye enhanced fluorescence imaging of GI mucosa: metaplasia, neoplasia, inflammation.

    PubMed

    Thekkek, Nadhi; Muldoon, Timothy; Polydorides, Alexandros D; Maru, Dipen M; Harpaz, Noam; Harris, Michael T; Hofstettor, Wayne; Hiotis, Spiros P; Kim, Sanghyun A; Ky, Alex Jenny; Anandasabapathy, Sharmila; Richards-Kortum, Rebecca

    2012-04-01

    Confocal endomicroscopy has revolutionized endoscopy by offering subcellular images of the GI epithelium; however, the field of view is limited. Multiscale endoscopy platforms that use widefield imaging are needed to better direct the placement of high-resolution probes. Feasibility study. This study evaluated the feasibility of a single agent, proflavine hemisulfate, as a contrast medium during both widefield and high-resolution imaging to characterize the morphologic changes associated with a variety of GI conditions. The University of Texas MD Anderson Cancer Center, Houston, Texas, and Mount Sinai Medical Center, New York, New York. PATIENTS, INTERVENTIONS, AND MAIN OUTCOME MEASUREMENTS: Resected specimens were obtained from 15 patients undergoing EMR, esophagectomy, or colectomy. Proflavine hemisulfate, a vital fluorescent dye, was applied topically. The specimens were imaged with a widefield multispectral microscope and a high-resolution microendoscope. The images were compared with histopathologic examination. Widefield fluorescence imaging enhanced visualization of morphology, including the presence and spatial distribution of glands, glandular distortion, atrophy, and crowding. High-resolution imaging of widefield abnormal areas revealed that neoplastic progression corresponded to glandular heterogeneity and nuclear crowding in dysplasia, with glandular effacement in carcinoma. These widefield and high-resolution image features correlated well with the histopathologic features. This imaging approach must be validated in vivo with a larger sample size. Multiscale proflavine-enhanced fluorescence imaging can delineate epithelial changes in a variety of GI conditions. Distorted glandular features seen with widefield imaging could serve as a critical bridge to high-resolution probe placement. An endoscopic platform combining the two modalities with a single vital dye may facilitate point-of-care decision making by providing real-time, in vivo diagnoses. Copyright © 2012 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.

  7. Estimation of Global 1km-grid Terrestrial Carbon Exchange Part II: Evaluations and Applications

    NASA Astrophysics Data System (ADS)

    Murakami, K.; Sasai, T.; Kato, S.; Niwa, Y.; Saito, M.; Takagi, H.; Matsunaga, T.; Hiraki, K.; Maksyutov, S. S.; Yokota, T.

    2015-12-01

    Global terrestrial carbon cycle largely depends on a spatial pattern in land cover type, which is heterogeneously-distributed over regional and global scales. Many studies have been trying to reveal distribution of carbon exchanges between terrestrial ecosystems and atmosphere for understanding global carbon cycle dynamics by using terrestrial biosphere models, satellite data, inventory data, and so on. However, most studies remained within several tens of kilometers grid spatial resolution, and the results have not been enough to understand the detailed pattern of carbon exchanges based on ecological community and to evaluate the carbon stocks by forest ecosystems in each countries. Improving the sophistication of spatial resolution is obviously necessary to enhance the accuracy of carbon exchanges. Moreover, the improvement may contribute to global warming awareness, policy makers and other social activities. We show global terrestrial carbon exchanges (net ecosystem production, net primary production, and gross primary production) with 1km-grid resolution. The methodology for these estimations are shown in the 2015 AGU FM poster "Estimation of Global 1km-grid Terrestrial Carbon Exchange Part I: Developing Inputs and Modelling". In this study, we evaluated the carbon exchanges in various regions with other approaches. We used the satellite-driven biosphere model (BEAMS) as our estimations, GOSAT L4A CO2 flux data, NEP retrieved by NICAM and CarbonTracer2013 flux data, for period from Jun 2001 to Dec 2012. The temporal patterns for this period were indicated similar trends between BEAMS, GOSAT, NICAM, and CT2013 in many sub-continental regions. Then, we estimated the terrestrial carbon exchanges in each countries, and could indicated the temporal patterns of the exchanges in large carbon stock regions.Global terrestrial carbon cycle largely depends on a spatial pattern of land cover type, which is heterogeneously-distributed over regional and global scales. Many studies have been trying to reveal distribution of carbon exchanges between terrestrial ecosystems and atmosphere for understanding global carbon cycle dynamics by using terrestrial biosphere models, satellite data, inventory data, and so on. However, most studies remained within several tens of kilometers grid spatial resolution, and the results have not been enough to understand the detailed pattern of carbon exchanges based on ecological community and to evaluate the carbon stocks by forest ecosystems in each countries. Improving the sophistication of spatial resolution is obviously necessary to enhance the accuracy of carbon exchanges. Moreover, the improvement may contribute to global warming awareness, policy makers and other social activities. We show global terrestrial carbon exchanges (net ecosystem production, net primary production, and gross primary production) with 1km-grid resolution. The methodology for these estimations are shown in the 2015 AGU FM poster "Estimation of Global 1km-grid Terrestrial Carbon Exchange Part I: Developing Inputs and Modelling". In this study, we evaluated the carbon exchanges in various regions with other approaches. We used the satellite-driven biosphere model (BEAMS) as our estimations, GOSAT L4A CO2 flux data, NEP retrieved by NICAM and CarbonTracer2013 flux data, for period from Jun 2001 to Dec 2012. The temporal patterns for this period were indicated similar trends between BEAMS, GOSAT, NICAM, and CT2013 in many sub-continental regions. Then, we estimated the terrestrial carbon exchanges in each countries, and could indicated the temporal patterns of the exchanges in large carbon stock regions.

  8. The research of road and vehicle information extraction algorithm based on high resolution remote sensing image

    NASA Astrophysics Data System (ADS)

    Zhou, Tingting; Gu, Lingjia; Ren, Ruizhi; Cao, Qiong

    2016-09-01

    With the rapid development of remote sensing technology, the spatial resolution and temporal resolution of satellite imagery also have a huge increase. Meanwhile, High-spatial-resolution images are becoming increasingly popular for commercial applications. The remote sensing image technology has broad application prospects in intelligent traffic. Compared with traditional traffic information collection methods, vehicle information extraction using high-resolution remote sensing image has the advantages of high resolution and wide coverage. This has great guiding significance to urban planning, transportation management, travel route choice and so on. Firstly, this paper preprocessed the acquired high-resolution multi-spectral and panchromatic remote sensing images. After that, on the one hand, in order to get the optimal thresholding for image segmentation, histogram equalization and linear enhancement technologies were applied into the preprocessing results. On the other hand, considering distribution characteristics of road, the normalized difference vegetation index (NDVI) and normalized difference water index (NDWI) were used to suppress water and vegetation information of preprocessing results. Then, the above two processing result were combined. Finally, the geometric characteristics were used to completed road information extraction. The road vector extracted was used to limit the target vehicle area. Target vehicle extraction was divided into bright vehicles extraction and dark vehicles extraction. Eventually, the extraction results of the two kinds of vehicles were combined to get the final results. The experiment results demonstrated that the proposed algorithm has a high precision for the vehicle information extraction for different high resolution remote sensing images. Among these results, the average fault detection rate was about 5.36%, the average residual rate was about 13.60% and the average accuracy was approximately 91.26%.

  9. Overhauser enhanced magnetic resonance imaging for tumor oximetry: Coregistration of tumor anatomy and tissue oxygen concentration

    NASA Astrophysics Data System (ADS)

    Krishna, Murali C.; English, Sean; Yamada, Kenichi; Yoo, John; Murugesan, Ramachandran; Devasahayam, Nallathamby; Cook, John A.; Golman, Klaes; Ardenkjaer-Larsen, Jan Henrik; Subramanian, Sankaran; Mitchell, James B.

    2002-02-01

    An efficient noninvasive method for in vivo imaging of tumor oxygenation by using a low-field magnetic resonance scanner and a paramagnetic contrast agent is described. The methodology is based on Overhauser enhanced magnetic resonance imaging (OMRI), a functional imaging technique. OMRI experiments were performed on tumor-bearing mice (squamous cell carcinoma) by i.v. administration of the contrast agent Oxo63 (a highly derivatized triarylmethyl radical) at nontoxic doses in the range of 2-7 mmol/kg either as a bolus or as a continuous infusion. Spatially resolved pO2 (oxygen concentration) images from OMRI experiments of tumor-bearing mice exhibited heterogeneous oxygenation profiles and revealed regions of hypoxia in tumors (<10 mmHg; 1 mmHg = 133 Pa). Oxygenation of tumors was enhanced on carbogen (95% O2/5% CO2) inhalation. The pO2 measurements from OMRI were found to be in agreement with those obtained by independent polarographic measurements using a pO2 Eppendorf electrode. This work illustrates that anatomically coregistered pO2 maps of tumors can be readily obtained by combining the good anatomical resolution of water proton-based MRI, and the superior pO2 sensitivity of EPR. OMRI affords the opportunity to perform noninvasive and repeated pO2 measurements of the same animal with useful spatial (≈1 mm) and temporal (2 min) resolution, making this method a powerful imaging modality for small animal research to understand tumor physiology and potentially for human applications.

  10. High resolution change estimation of soil moisture and its assimilation into a land surface model

    NASA Astrophysics Data System (ADS)

    Narayan, Ujjwal

    Near surface soil moisture plays an important role in hydrological processes including infiltration, evapotranspiration and runoff. These processes depend non-linearly on soil moisture and hence sub-pixel scale soil moisture variability characterization is important for accurate modeling of water and energy fluxes at the pixel scale. Microwave remote sensing has evolved as an attractive technique for global monitoring of near surface soil moisture. A radiative transfer model has been tested and validated for soil moisture retrieval from passive microwave remote sensing data under a full range of vegetation water content conditions. It was demonstrated that soil moisture retrieval errors of approximately 0.04 g/g gravimetric soil moisture are attainable with vegetation water content as high as 5 kg/m2. Recognizing the limitation of low spatial resolution associated with passive sensors, an algorithm that uses low resolution passive microwave (radiometer) and high resolution active microwave (radar) data to estimate soil moisture change at the spatial resolution of radar operation has been developed and applied to coincident Passive and Active L and S band (PALS) and Airborne Synthetic Aperture Radar (AIRSAR) datasets acquired during the Soil Moisture Experiments in 2002 (SMEX02) campaign with root mean square error of 10% and a 4 times enhancement in spatial resolution. The change estimation algorithm has also been used to estimate soil moisture change at 5 km resolution using AMSR-E soil moisture product (50 km) in conjunction with the TRMM-PR data (5 km) for a 3 month period demonstrating the possibility of high resolution soil moisture change estimation using satellite based data. Soil moisture change is closely related to precipitation and soil hydraulic properties. A simple assimilation framework has been implemented to investigate whether assimilation of surface layer soil moisture change observations into a hydrologic model will potentially improve it performance. Results indicate an improvement in model prediction of near surface and deep layer soil moisture content when the update is performed to the model state as compared to free model runs. It is also seen that soil moisture change assimilation is able to mitigate the effect of erroneous precipitation input data.

  11. Reducing the spatial resolution range of neutron radiographs cast by thick objects

    NASA Astrophysics Data System (ADS)

    Almeida, G. L.; Silvani, M. I.; Souza, E. S.; Lopes, R. T.

    2017-11-01

    The quality of a neutron radiograph is strongly dependent upon the features of the acquisition system. Most of them, such as detector resolution, electronic noise and statistical fluctuation can hardly be improved. Yet, a main parameter ruling the image spatial resolution, namely the L/D ratio of the system can be increased simply by lengthening the source-detector clearance. Such an option eventually may not be feasible due to neutron flux decreasing or engineering constraints. Under this circumstance, a radiograph improvement is only possible by some kind of after-acquisition procedure capable to retrieve, at least partially, the information concealed by the degradation process. Since the spoiling agent tied to the L/D has a systematic character, its impact can be reduced by an unfolding procedure such as Richardson-Lucy algorithm. However, that agent should be fully characterized and furnished to the algorithm as a Point Spread Function - PSF unfolding function. A main drawback of unfolding algorithms like Richardson-Lucy is that the PSF should be fixed, i.e., it assumes a certain constant image spatial resolution, rather than a variable one as actually occurs for thick objects. This work presents a methodology to minimize this difficulty by making all planes of the inspected object to cast a resolution within the shorter gap comprised between the object central plane and the detector. The image can then be unfolded with a lower resolution within a tighter range, yielding a better quality. The process is performed with two radiographs, where one of them is acquired with the object turned by 180° on its vertical axis with regard to the other. After a mirroring of one of them about its vertical axis, the images are added. As the resolution increases linearly with the object-detector gap, it would remain always lower than that of the central one. Therefore, the overall resolution of the composite radiograph is enhanced. A further improvement can then be achieved through an efficient unfolding since the object has been virtually shrunk along the neutron path.

  12. Effect of contrast enhancement prior to iteration procedure on image correction for soft x-ray projection microscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jamsranjav, Erdenetogtokh, E-mail: ja.erdenetogtokh@gmail.com; Shiina, Tatsuo, E-mail: shiina@faculity.chiba-u.jp; Kuge, Kenichi

    2016-01-28

    Soft X-ray microscopy is well recognized as a powerful tool of high-resolution imaging for hydrated biological specimens. Projection type of it has characteristics of easy zooming function, simple optical layout and so on. However the image is blurred by the diffraction of X-rays, leading the spatial resolution to be worse. In this study, the blurred images have been corrected by an iteration procedure, i.e., Fresnel and inverse Fresnel transformations repeated. This method was confirmed by earlier studies to be effective. Nevertheless it was not enough to some images showing too low contrast, especially at high magnification. In the present study,more » we tried a contrast enhancement method to make the diffraction fringes clearer prior to the iteration procedure. The method was effective to improve the images which were not successful by iteration procedure only.« less

  13. Polarization Sensitive Coherent Anti-Stokes Raman Spectroscopy of DCVJ in Doped Polymer

    NASA Astrophysics Data System (ADS)

    Ujj, Laszlo

    2014-05-01

    Coherent Raman Microscopy is an emerging technic and method to image biological samples such as living cells by recording vibrational fingerprints of molecules with high spatial resolution. The race is on to record the entire image during the shortest time possible in order to increase the time resolution of the recorded cellular events. The electronically enhanced polarization sensitive version of Coherent anti-Stokes Raman scattering is one of the method which can shorten the recording time and increase the sharpness of an image by enhancing the signal level of special molecular vibrational modes. In order to show the effectiveness of the method a model system, a highly fluorescence sample, DCVJ in a polymer matrix is investigated. Polarization sensitive resonance CARS spectra are recorded and analyzed. Vibrational signatures are extracted with model independent methods. Details of the measurements and data analysis will be presented. The author gratefully acknowledge the UWF for financial support.

  14. Satellite-based high-resolution PM2.5 estimation over the Beijing-Tianjin-Hebei region of China using an improved geographically and temporally weighted regression model.

    PubMed

    He, Qingqing; Huang, Bo

    2018-05-01

    Ground fine particulate matter (PM2.5) concentrations at high spatial resolution are substantially required for determining the population exposure to PM2.5 over densely populated urban areas. However, most studies for China have generated PM2.5 estimations at a coarse resolution (≥10 km) due to the limitation of satellite aerosol optical depth (AOD) product in spatial resolution. In this study, the 3 km AOD data fused using the Moderate Resolution Imaging Spectroradiometer (MODIS) Collection 6 AOD products were employed to estimate the ground PM2.5 concentrations over the Beijing-Tianjin-Hebei (BTH) region of China from January 2013 to December 2015. An improved geographically and temporally weighted regression (iGTWR) model incorporating seasonal characteristics within the data was developed, which achieved comparable performance to the standard GTWR model for the days with paired PM 2.5 - AOD samples (Cross-validation (CV) R 2  = 0.82) and showed better predictive power for the days without PM 2.5 - AOD pairs (the R 2 increased from 0.24 to 0.46 in CV). Both iGTWR and GTWR (CV R 2  = 0.84) significantly outperformed the daily geographically weighted regression model (CV R 2  = 0.66). Also, the fused 3 km AODs improved data availability and presented more spatial gradients, thereby enhancing model performance compared with the MODIS original 3/10 km AOD product. As a result, ground PM2.5 concentrations at higher resolution were well represented, allowing, e.g., short-term pollution events and long-term PM2.5 trend to be identified, which, in turn, indicated that concerns about air pollution in the BTH region are justified despite its decreasing trend from 2013 to 2015. Copyright © 2018 Elsevier Ltd. All rights reserved.

  15. Evaluating the Value of High Spatial Resolution in National Capacity Expansion Models using ReEDS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Krishnan, Venkat; Cole, Wesley

    2016-11-14

    Power sector capacity expansion models (CEMs) have a broad range of spatial resolutions. This paper uses the Regional Energy Deployment System (ReEDS) model, a long-term national scale electric sector CEM, to evaluate the value of high spatial resolution for CEMs. ReEDS models the United States with 134 load balancing areas (BAs) and captures the variability in existing generation parameters, future technology costs, performance, and resource availability using very high spatial resolution data, especially for wind and solar modeled at 356 resource regions. In this paper we perform planning studies at three different spatial resolutions--native resolution (134 BAs), state-level, and NERCmore » region level--and evaluate how results change under different levels of spatial aggregation in terms of renewable capacity deployment and location, associated transmission builds, and system costs. The results are used to ascertain the value of high geographically resolved models in terms of their impact on relative competitiveness among renewable energy resources.« less

  16. Magnetic resonance imaging with an optical atomic magnetometer

    PubMed Central

    Xu, Shoujun; Yashchuk, Valeriy V.; Donaldson, Marcus H.; Rochester, Simon M.; Budker, Dmitry; Pines, Alexander

    2006-01-01

    We report an approach for the detection of magnetic resonance imaging without superconducting magnets and cryogenics: optical atomic magnetometry. This technique possesses a high sensitivity independent of the strength of the static magnetic field, extending the applicability of magnetic resonance imaging to low magnetic fields and eliminating imaging artifacts associated with high fields. By coupling with a remote-detection scheme, thereby improving the filling factor of the sample, we obtained time-resolved flow images of water with a temporal resolution of 0.1 s and spatial resolutions of 1.6 mm perpendicular to the flow and 4.5 mm along the flow. Potentially inexpensive, compact, and mobile, our technique provides a viable alternative for MRI detection with substantially enhanced sensitivity and time resolution for various situations where traditional MRI is not optimal. PMID:16885210

  17. High resolution main-ion charge exchange spectroscopy in the DIII-D H-mode pedestal.

    PubMed

    Grierson, B A; Burrell, K H; Chrystal, C; Groebner, R J; Haskey, S R; Kaplan, D H

    2016-11-01

    A new high spatial resolution main-ion (deuterium) charge-exchange spectroscopy system covering the tokamak boundary region has been installed on the DIII-D tokamak. Sixteen new edge main-ion charge-exchange recombination sightlines have been combined with nineteen impurity sightlines in a tangentially viewing geometry on the DIII-D midplane with an interleaving design that achieves 8 mm inter-channel radial resolution for detailed profiles of main-ion temperature, velocity, charge-exchange emission, and neutral beam emission. At the plasma boundary, we find a strong enhancement of the main-ion toroidal velocity that exceeds the impurity velocity by a factor of two. The unique combination of experimentally measured main-ion and impurity profiles provides a powerful quasi-neutrality constraint for reconstruction of tokamak H-mode pedestals.

  18. The Eyephone: a head-mounted stereo display

    NASA Astrophysics Data System (ADS)

    Teitel, Michael A.

    1990-09-01

    Head mounted stereo displays for virtual environments and computer simulations have been made since 1969. Most of the recent displays have been based on monochrome (black and white) liquid crystal display technology. Color LCD displays have generally not been used due to their lower resolution and color triad structure. As the resolution of color LCDdisplays is increasing we have begun to use color displays in our Eyephone. In this paper we describe four methods for minimizing the effect of the color triads in the magnified images of LCD displays in the Eyephone stereo head mounted display. We have settled on the use of wavefront randomizer with a spatial frequency enhancement overlay in order to blur the triacis in the displays while keeping the perceived resolution of the display high.

  19. The Analysis of Burrows Recognition Accuracy in XINJIANG'S Pasture Area Based on Uav Visible Images with Different Spatial Resolution

    NASA Astrophysics Data System (ADS)

    Sun, D.; Zheng, J. H.; Ma, T.; Chen, J. J.; Li, X.

    2018-04-01

    The rodent disaster is one of the main biological disasters in grassland in northern Xinjiang. The eating and digging behaviors will cause the destruction of ground vegetation, which seriously affected the development of animal husbandry and grassland ecological security. UAV low altitude remote sensing, as an emerging technique with high spatial resolution, can effectively recognize the burrows. However, how to select the appropriate spatial resolution to monitor the calamity of the rodent disaster is the first problem we need to pay attention to. The purpose of this study is to explore the optimal spatial scale on identification of the burrows by evaluating the impact of different spatial resolution for the burrows identification accuracy. In this study, we shoot burrows from different flight heights to obtain visible images of different spatial resolution. Then an object-oriented method is used to identify the caves, and we also evaluate the accuracy of the classification. We found that the highest classification accuracy of holes, the average has reached more than 80 %. At the altitude of 24 m and the spatial resolution of 1cm, the accuracy of the classification is the highest We have created a unique and effective way to identify burrows by using UAVs visible images. We draw the following conclusion: the best spatial resolution of burrows recognition is 1 cm using DJI PHANTOM-3 UAV, and the improvement of spatial resolution does not necessarily lead to the improvement of classification accuracy. This study lays the foundation for future research and can be extended to similar studies elsewhere.

  20. Super-resolved refocusing with a plenoptic camera

    NASA Astrophysics Data System (ADS)

    Zhou, Zhiliang; Yuan, Yan; Bin, Xiangli; Qian, Lulu

    2011-03-01

    This paper presents an approach to enhance the resolution of refocused images by super resolution methods. In plenoptic imaging, we demonstrate that the raw sensor image can be divided to a number of low-resolution angular images with sub-pixel shifts between each other. The sub-pixel shift, which defines the super-resolving ability, is mathematically derived by considering the plenoptic camera as equivalent camera arrays. We implement simulation to demonstrate the imaging process of a plenoptic camera. A high-resolution image is then reconstructed using maximum a posteriori (MAP) super resolution algorithms. Without other degradation effects in simulation, the super resolved image achieves a resolution as high as predicted by the proposed model. We also build an experimental setup to acquire light fields. With traditional refocusing methods, the image is rendered at a rather low resolution. In contrast, we implement the super-resolved refocusing methods and recover an image with more spatial details. To evaluate the performance of the proposed method, we finally compare the reconstructed images using image quality metrics like peak signal to noise ratio (PSNR).

  1. Impact of Urbanization on Spatial Variability of Rainfall-A case study of Mumbai city with WRF Model

    NASA Astrophysics Data System (ADS)

    Mathew, M.; Paul, S.; Devanand, A.; Ghosh, S.

    2015-12-01

    Urban precipitation enhancement has been identified over many cities in India by previous studies conducted. Anthropogenic effects such as change in land cover from hilly forest areas to flat topography with solid concrete infrastructures has certain effect on the local weather, the same way the greenhouse gas has on climate change. Urbanization could alter the large scale forcings to such an extent that it may bring about temporal and spatial changes in the urban weather. The present study investigate the physical processes involved in urban forcings, such as the effect of sudden increase in wind velocity travelling through the channel space in between the dense array of buildings, which give rise to turbulence and air mass instability in urban boundary layer and in return alters the rainfall distribution as well as rainfall initiation. A numerical model study is conducted over Mumbai metropolitan city which lies on the west coast of India, to assess the effect of urban morphology on the increase in number of extreme rainfall events in specific locations. An attempt has been made to simulate twenty extreme rainfall events that occurred over the summer monsoon period of the year 2014 using high resolution WRF-ARW (Weather Research and Forecasting-Advanced Research WRF) model to assess the urban land cover mechanisms that influences precipitation variability over this spatially varying urbanized region. The result is tested against simulations with altered land use. The correlation of precipitation with spatial variability of land use is found using a detailed urban land use classification. The initial and boundary conditions for running the model were obtained from the global model ECMWF(European Centre for Medium Range Weather Forecast) reanalysis data having a horizontal resolution of 0.75 °x 0.75°. The high resolution simulations show significant spatial variability in the accumulated rainfall, within a few kilometers itself. Understanding the spatial variability of precipitation will help in the planning and management of the built environment more efficiently.

  2. Reconstructing Spectral Scenes Using Statistical Estimation to Enhance Space Situational Awareness

    DTIC Science & Technology

    2006-12-01

    simultane- ously spatially and spectrally deblur the images collected from ASIS. The algorithms are based on proven estimation theories and do not...collected with any system using a filtering technology known as Electronic Tunable Filters (ETFs). Previous methods to deblur spectral images collected...spectrally deblurring then the previously investigated methods. This algorithm expands on a method used for increasing the spectral resolution in gamma-ray

  3. Supersampling multiframe blind deconvolution resolution enhancement of adaptive-optics-compensated imagery of LEO satellites

    NASA Astrophysics Data System (ADS)

    Gerwe, David R.; Lee, David J.; Barchers, Jeffrey D.

    2000-10-01

    A post-processing methodology for reconstructing undersampled image sequences with randomly varying blur is described which can provide image enhancement beyond the sampling resolution of the sensor. This method is demonstrated on simulated imagery and on adaptive optics compensated imagery taken by the Starfire Optical Range 3.5 meter telescope that has been artificially undersampled. Also shown are the results of multiframe blind deconvolution of some of the highest quality optical imagery of low earth orbit satellites collected with a ground based telescope to date. The algorithm used is a generalization of multiframe blind deconvolution techniques which includes a representation of spatial sampling by the focal plane array elements in the forward stochastic model of the imaging system. This generalization enables the random shifts and shape of the adaptive compensated PSF to be used to partially eliminate the aliasing effects associated with sub- Nyquist sampling of the image by the focal plane array. The method could be used to reduce resolution loss which occurs when imaging in wide FOV modes.

  4. Supersampling multiframe blind deconvolution resolution enhancement of adaptive optics compensated imagery of low earth orbit satellites

    NASA Astrophysics Data System (ADS)

    Gerwe, David R.; Lee, David J.; Barchers, Jeffrey D.

    2002-09-01

    We describe a postprocessing methodology for reconstructing undersampled image sequences with randomly varying blur that can provide image enhancement beyond the sampling resolution of the sensor. This method is demonstrated on simulated imagery and on adaptive-optics-(AO)-compensated imagery taken by the Starfire Optical Range 3.5-m telescope that has been artificially undersampled. Also shown are the results of multiframe blind deconvolution of some of the highest quality optical imagery of low earth orbit satellites collected with a ground-based telescope to date. The algorithm used is a generalization of multiframe blind deconvolution techniques that include a representation of spatial sampling by the focal plane array elements based on a forward stochastic model. This generalization enables the random shifts and shape of the AO- compensated point spread function (PSF) to be used to partially eliminate the aliasing effects associated with sub-Nyquist sampling of the image by the focal plane array. The method could be used to reduce resolution loss that occurs when imaging in wide- field-of-view (FOV) modes.

  5. Instantaneous velocity measurement of AC electroosmotic flows by laser induced fluorescence photobleaching anemometer with high temporal resolution

    NASA Astrophysics Data System (ADS)

    Zhao, Wei; Yang, Fang; Qiao, Rui; Wang, Guiren; Rui Qiao Collaboration

    2015-11-01

    Understanding the instantaneous response of flows to applied AC electric fields may help understand some unsolved issues in induced-charge electrokinetics and enhance performance of microfluidic devices. Since currently available velocimeters have difficulty in measuring velocity fluctuations with frequency higher than 1 kHz, most experimental studies so far focus only on the average velocity measurement in AC electrokinetic flows. Here, we present measurements of AC electroosmotic flow (AC-EOF) response time in microchannels by a novel velocimeter with submicrometer spatial resolution and microsecond temporal resolution, i.e. laser-induced fluorescence photobleaching anemometer (LIFPA). Several parameters affecting the AC-EOF response time to the applied electric signal were investigated, i.e. channel length, transverse position and solution conductivity. The experimental results show that the EOF response time under a pulsed electric field decreases with the reduction of the microchannel length, distance between the detection position to the wall and the conductivity of the solution. This work could provide a new powerful tool to measure AC electrokinetics and enhance our understanding of AC electrokinetic flows.

  6. Experimental evaluation and basis function optimization of the spatially variant image-space PSF on the Ingenuity PET/MR scanner

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kotasidis, Fotis A., E-mail: Fotis.Kotasidis@unige.ch; Zaidi, Habib; Geneva Neuroscience Centre, Geneva University, CH-1205 Geneva

    2014-06-15

    Purpose: The Ingenuity time-of-flight (TF) PET/MR is a recently developed hybrid scanner combining the molecular imaging capabilities of PET with the excellent soft tissue contrast of MRI. It is becoming common practice to characterize the system's point spread function (PSF) and understand its variation under spatial transformations to guide clinical studies and potentially use it within resolution recovery image reconstruction algorithms. Furthermore, due to the system's utilization of overlapping and spherical symmetric Kaiser-Bessel basis functions during image reconstruction, its image space PSF and reconstructed spatial resolution could be affected by the selection of the basis function parameters. Hence, a detailedmore » investigation into the multidimensional basis function parameter space is needed to evaluate the impact of these parameters on spatial resolution. Methods: Using an array of 12 × 7 printed point sources, along with a custom made phantom, and with the MR magnet on, the system's spatially variant image-based PSF was characterized in detail. Moreover, basis function parameters were systematically varied during reconstruction (list-mode TF OSEM) to evaluate their impact on the reconstructed resolution and the image space PSF. Following the spatial resolution optimization, phantom, and clinical studies were subsequently reconstructed using representative basis function parameters. Results: Based on the analysis and under standard basis function parameters, the axial and tangential components of the PSF were found to be almost invariant under spatial transformations (∼4 mm) while the radial component varied modestly from 4 to 6.7 mm. Using a systematic investigation into the basis function parameter space, the spatial resolution was found to degrade for basis functions with a large radius and small shape parameter. However, it was found that optimizing the spatial resolution in the reconstructed PET images, while having a good basis function superposition and keeping the image representation error to a minimum, is feasible, with the parameter combination range depending upon the scanner's intrinsic resolution characteristics. Conclusions: Using the printed point source array as a MR compatible methodology for experimentally measuring the scanner's PSF, the system's spatially variant resolution properties were successfully evaluated in image space. Overall the PET subsystem exhibits excellent resolution characteristics mainly due to the fact that the raw data are not under-sampled/rebinned, enabling the spatial resolution to be dictated by the scanner's intrinsic resolution and the image reconstruction parameters. Due to the impact of these parameters on the resolution properties of the reconstructed images, the image space PSF varies both under spatial transformations and due to basis function parameter selection. Nonetheless, for a range of basis function parameters, the image space PSF remains unaffected, with the range depending on the scanner's intrinsic resolution properties.« less

  7. Normal-incidence EXtreme-Ultraviolet imaging Spectrometer - NEXUS

    NASA Astrophysics Data System (ADS)

    Dere, K. P.

    2003-05-01

    NEXUS is the result of a breakthrough optical design that incorporates new technologies to achieve high optical throughput at high spatial (1 arcsec) and spectral (1-2 km s-1) resolution over a wide field of view in an optimal extreme-ultraviolet spectral band. This achievement was made possible primarily by two technical developments. First, a coating of boron-carbide deposited onto a layer of iridium provided a greatly enhanced reflectivity at EUV wavelengths that would enable NEXUS to observe the Sun over a wide temperature range at high cadence. The reflectivity of these coatings have been measured and demonstrated in the laboratory. The second key development was the use of a variable-line-spaced toroidal grating spectrometer. The spectrometer design allowed the Sun to be imaged at high spatial and spectral resolution along a 1 solar radius-long slit and over a wavelength range from 450 to 800 Å, nearly an entire spectral order. Because the spectrograph provided a magnification of about a factor of 6, only 2 optical elements are required to achieved the desired imaging performance. Throughput was enhanced by the use of only 2 reflections. The could all be accomodated within a total instrument length of 1.5m. We would like to acknowledge support from ONR

  8. Analysis of extreme rain and flood events using a regional hydrologically enhanced hydrometeorological system

    NASA Astrophysics Data System (ADS)

    Yucel, Ismail; Onen, Alper

    2013-04-01

    Evidence is showing that global warming or climate change has a direct influence on changes in precipitation and the hydrological cycle. Extreme weather events such as heavy rainfall and flooding are projected to become much more frequent as climate warms. Regional hydrometeorological system model which couples the atmosphere with physical and gridded based surface hydrology provide efficient predictions for extreme hydrological events. This modeling system can be used for flood forecasting and warning issues as they provide continuous monitoring of precipitation over large areas at high spatial resolution. This study examines the performance of the Weather Research and Forecasting (WRF-Hydro) model that performs the terrain, sub-terrain, and channel routing in producing streamflow from WRF-derived forcing of extreme precipitation events. The capability of the system with different options such as data assimilation is tested for number of flood events observed in basins of western Black Sea Region in Turkey. Rainfall event structures and associated flood responses are evaluated with gauge and satellite-derived precipitation and measured streamflow values. The modeling system shows skills in capturing the spatial and temporal structure of extreme rainfall events and resulted flood hydrographs. High-resolution routing modules activated in the model enhance the simulated discharges.

  9. Dione's spectral and geological properties

    USGS Publications Warehouse

    Stephan, K.; Jaumann, R.; Wagner, R.; Clark, R.N.; Cruikshank, D.P.; Hibbitts, C.A.; Roatsch, T.; Hoffmann, H.; Brown, R.H.; Filiacchione, G.; Buratti, B.J.; Hansen, G.B.; McCord, T.B.; Nicholson, P.D.; Baines, K.H.

    2010-01-01

    We present a detailed analysis of the variations in spectral properties across the surface of Saturn's satellite Dione using Cassini/VIMS data and their relationships to geological and/or morphological characteristics as seen in the Cassini/ISS images. This analysis focuses on a local region on Dione's anti-saturnian hemisphere that was observed by VIMS with high spatial resolution during orbit 16 in October 2005. The results are incorporated into a global context provided by VIMS data acquired within Cassini's first 50 orbits. Our results show that Dione's surface is dominated by at least one global process. Bombardment by magnetospheric particles is consistent with the concentration of dark material and enhanced CO2 absorption on the trailing hemisphere of Dione independent of the geology. Local regions within this terrain indicate a special kind of resurfacing that probably is related to large-scale impact process. In contrast, the enhanced ice signature on the leading side is associated with the extended ejecta of the fresh impact crater Creusa (???49??N/76??W). Although no geologically active regions could be identified, Dione's tectonized regions observed with high spatial resolution partly show some clean H2O ice implying that tectonic processes could have continued into more recent times. ?? 2009 Elsevier Inc. All rights reserved.

  10. Regional Scale High Resolution δ18O Prediction in Precipitation Using MODIS EVI

    PubMed Central

    Huang, Cho-Ying; Wang, Chung-Ho; Lin, Shou-De; Lo, Yi-Chen; Huang, Bo-Wen; Hatch, Kent A.; Shiu, Hau-Jie; You, Cheng-Feng; Chang, Yuan-Mou; Shen, Sheng-Feng

    2012-01-01

    The natural variation in stable water isotope ratio data, also known as water isoscape, is a spatiotemporal fingerprint and a powerful natural tracer that has been widely applied in disciplines as diverse as hydrology, paleoclimatology, ecology and forensic investigation. Although much effort has been devoted to developing a predictive water isoscape model, it remains a central challenge for scientists to generate high accuracy, fine scale spatiotemporal water isoscape prediction. Here we develop a novel approach of using the MODIS-EVI (the Moderate Resolution Imagining Spectroradiometer-Enhanced Vegetation Index), to predict δ18O in precipitation at the regional scale. Using a structural equation model, we show that the EVI and precipitated δ18O are highly correlated and thus the EVI is a good predictor of precipitated δ18O. We then test the predictability of our EVI-δ18O model and demonstrate that our approach can provide high accuracy with fine spatial (250×250 m) and temporal (16 days) scale δ18O predictions (annual and monthly predictabilities [r] are 0.96 and 0.80, respectively). We conclude the merging of the EVI and δ18O in precipitation can greatly extend the spatial and temporal data availability and thus enhance the applicability for both the EVI and water isoscape. PMID:23029053

  11. An evaluation of spatial resolution of a prototype proton CT scanner.

    PubMed

    Plautz, Tia E; Bashkirov, V; Giacometti, V; Hurley, R F; Johnson, R P; Piersimoni, P; Sadrozinski, H F-W; Schulte, R W; Zatserklyaniy, A

    2016-12-01

    To evaluate the spatial resolution of proton CT using both a prototype proton CT scanner and Monte Carlo simulations. A custom cylindrical edge phantom containing twelve tissue-equivalent inserts with four different compositions at varying radial displacements from the axis of rotation was developed for measuring the modulation transfer function (MTF) of a prototype proton CT scanner. Two scans of the phantom, centered on the axis of rotation, were obtained with a 200 MeV, low-intensity proton beam: one scan with steps of 4°, and one scan with the phantom continuously rotating. In addition, Monte Carlo simulations of the phantom scan were performed using scanners idealized to various degrees. The data were reconstructed using an iterative projection method with added total variation superiorization based on individual proton histories. Edge spread functions in the radial and azimuthal directions were obtained using the oversampling technique. These were then used to obtain the modulation transfer functions. The spatial resolution was defined by the 10% value of the modulation transfer function (MTF 10% ) in units of line pairs per centimeter (lp/cm). Data from the simulations were used to better understand the contributions of multiple Coulomb scattering in the phantom and the scanner hardware, as well as the effect of discretization of proton location. The radial spatial resolution of the prototype proton CT scanner depends on the total path length, W, of the proton in the phantom, whereas the azimuthal spatial resolution depends both on W and the position, u - , at which the most-likely path uncertainty is evaluated along the path. For protons contributing to radial spatial resolution, W varies with the radial position of the edge, whereas for protons contributing to azimuthal spatial resolution, W is approximately constant. For a pixel size of 0.625 mm, the radial spatial resolution of the image reconstructed from the fully idealized simulation data ranged between 6.31 ± 0.36 lp/cm for W = 197 mm i.e., close to the center of the phantom, and 13.79 ± 0.36 lp/cm for W = 97 mm, near the periphery of the phantom. The azimuthal spatial resolution ranged from 6.99 ± 0.23 lp/cm at u - = 75 mm (near the center) to 11.20 ± 0.26 lp/cm at u - = 20 mm (near the periphery). Multiple Coulomb scattering limits the radial spatial resolution for path lengths greater than approximately 130 mm, and the azimuthal spatial resolution for positions of evaluation greater than approximately 40 mm for W = 199 mm. The radial spatial resolution of the image reconstructed from data from the 4° stepped experimental scan ranged from 5.11 ± 0.61 lp/cm for W = 197 mm to 8.58 ± 0.50 lp/cm for W = 97 mm. In the azimuthal direction, the spatial resolution ranged from 5.37 ± 0.40 lp/cm at u - = 75 mm to 7.27 ± 0.39 lp/cm at u - = 20 mm. The continuous scan achieved the same spatial resolution as that of the stepped scan. Multiple Coulomb scattering in the phantom is the limiting physical factor of the achievable spatial resolution of proton CT; additional loss of spatial resolution in the prototype system is associated with scattering in the proton tracking system and inadequacies of the proton path estimate used in the iterative reconstruction algorithm. Improvement in spatial resolution may be achievable by improving the most likely path estimate by incorporating information about high and low density materials, and by minimizing multiple Coulomb scattering in the proton tracking system.

  12. An evaluation of spatial resolution of a prototype proton CT scanner

    PubMed Central

    Plautz, Tia E.; Bashkirov, V.; Giacometti, V.; Hurley, R. F.; Piersimoni, P.; Sadrozinski, H. F.-W.; Schulte, R. W.; Zatserklyaniy, A.

    2016-01-01

    Purpose: To evaluate the spatial resolution of proton CT using both a prototype proton CT scanner and Monte Carlo simulations. Methods: A custom cylindrical edge phantom containing twelve tissue-equivalent inserts with four different compositions at varying radial displacements from the axis of rotation was developed for measuring the modulation transfer function (MTF) of a prototype proton CT scanner. Two scans of the phantom, centered on the axis of rotation, were obtained with a 200 MeV, low-intensity proton beam: one scan with steps of 4°, and one scan with the phantom continuously rotating. In addition, Monte Carlo simulations of the phantom scan were performed using scanners idealized to various degrees. The data were reconstructed using an iterative projection method with added total variation superiorization based on individual proton histories. Edge spread functions in the radial and azimuthal directions were obtained using the oversampling technique. These were then used to obtain the modulation transfer functions. The spatial resolution was defined by the 10% value of the modulation transfer function (MTF10%) in units of line pairs per centimeter (lp/cm). Data from the simulations were used to better understand the contributions of multiple Coulomb scattering in the phantom and the scanner hardware, as well as the effect of discretization of proton location. Results: The radial spatial resolution of the prototype proton CT scanner depends on the total path length, W, of the proton in the phantom, whereas the azimuthal spatial resolution depends both on W and the position, u−, at which the most-likely path uncertainty is evaluated along the path. For protons contributing to radial spatial resolution, W varies with the radial position of the edge, whereas for protons contributing to azimuthal spatial resolution, W is approximately constant. For a pixel size of 0.625 mm, the radial spatial resolution of the image reconstructed from the fully idealized simulation data ranged between 6.31 ± 0.36 lp/cm for W = 197 mm i.e., close to the center of the phantom, and 13.79 ± 0.36 lp/cm for W = 97 mm, near the periphery of the phantom. The azimuthal spatial resolution ranged from 6.99 ± 0.23 lp/cm at u− = 75 mm (near the center) to 11.20 ± 0.26 lp/cm at u− = 20 mm (near the periphery). Multiple Coulomb scattering limits the radial spatial resolution for path lengths greater than approximately 130 mm, and the azimuthal spatial resolution for positions of evaluation greater than approximately 40 mm for W = 199 mm. The radial spatial resolution of the image reconstructed from data from the 4° stepped experimental scan ranged from 5.11 ± 0.61 lp/cm for W = 197 mm to 8.58 ± 0.50 lp/cm for W = 97 mm. In the azimuthal direction, the spatial resolution ranged from 5.37 ± 0.40 lp/cm at u− = 75 mm to 7.27 ± 0.39 lp/cm at u− = 20 mm. The continuous scan achieved the same spatial resolution as that of the stepped scan. Conclusions: Multiple Coulomb scattering in the phantom is the limiting physical factor of the achievable spatial resolution of proton CT; additional loss of spatial resolution in the prototype system is associated with scattering in the proton tracking system and inadequacies of the proton path estimate used in the iterative reconstruction algorithm. Improvement in spatial resolution may be achievable by improving the most likely path estimate by incorporating information about high and low density materials, and by minimizing multiple Coulomb scattering in the proton tracking system. PMID:27908179

  13. Latin Hypercube Sampling (LHS) at variable resolutions for enhanced watershed scale Soil Sampling and Digital Soil Mapping.

    NASA Astrophysics Data System (ADS)

    Hamalainen, Sampsa; Geng, Xiaoyuan; He, Juanxia

    2017-04-01

    Latin Hypercube Sampling (LHS) at variable resolutions for enhanced watershed scale Soil Sampling and Digital Soil Mapping. Sampsa Hamalainen, Xiaoyuan Geng, and Juanxia, He. AAFC - Agriculture and Agr-Food Canada, Ottawa, Canada. The Latin Hypercube Sampling (LHS) approach to assist with Digital Soil Mapping has been developed for some time now, however the purpose of this work was to complement LHS with use of multiple spatial resolutions of covariate datasets and variability in the range of sampling points produced. This allowed for specific sets of LHS points to be produced to fulfil the needs of various partners from multiple projects working in the Ontario and Prince Edward Island provinces of Canada. Secondary soil and environmental attributes are critical inputs that are required in the development of sampling points by LHS. These include a required Digital Elevation Model (DEM) and subsequent covariate datasets produced as a result of a Digital Terrain Analysis performed on the DEM. These additional covariates often include but are not limited to Topographic Wetness Index (TWI), Length-Slope (LS) Factor, and Slope which are continuous data. The range of specific points created in LHS included 50 - 200 depending on the size of the watershed and more importantly the number of soil types found within. The spatial resolution of covariates included within the work ranged from 5 - 30 m. The iterations within the LHS sampling were run at an optimal level so the LHS model provided a good spatial representation of the environmental attributes within the watershed. Also, additional covariates were included in the Latin Hypercube Sampling approach which is categorical in nature such as external Surficial Geology data. Some initial results of the work include using a 1000 iteration variable within the LHS model. 1000 iterations was consistently a reasonable value used to produce sampling points that provided a good spatial representation of the environmental attributes. When working within the same spatial resolution for covariates, however only modifying the desired number of sampling points produced, the change of point location portrayed a strong geospatial relationship when using continuous data. Access to agricultural fields and adjacent land uses is often "pinned" as the greatest deterrent to performing soil sampling for both soil survey and soil attribute validation work. The lack of access can be a result of poor road access and/or difficult geographical conditions to navigate for field work individuals. This seems a simple yet continuous issue to overcome for the scientific community and in particular, soils professionals. The ability to assist with the ease of access to sampling points will be in the future a contribution to the Latin Hypercube Sampling (LHS) approach. By removing all locations in the initial instance from the DEM, the LHS model can be restricted to locations only with access from the adjacent road or trail. To further the approach, a road network geospatial dataset can be included within spatial Geographic Information Systems (GIS) applications to access already produced points using a shortest-distance network method.

  14. Effects of vegetation heterogeneity and surface topography on spatial scaling of net primary productivity

    NASA Astrophysics Data System (ADS)

    Chen, J. M.; Chen, X.; Ju, W.

    2013-03-01

    Due to the heterogeneous nature of the land surface, spatial scaling is an inevitable issue in the development of land models coupled with low-resolution Earth system models (ESMs) for predicting land-atmosphere interactions and carbon-climate feedbacks. In this study, a simple spatial scaling algorithm is developed to correct errors in net primary productivity (NPP) estimates made at a coarse spatial resolution based on sub-pixel information of vegetation heterogeneity and surface topography. An eco-hydrological model BEPS-TerrainLab, which considers both vegetation and topographical effects on the vertical and lateral water flows and the carbon cycle, is used to simulate NPP at 30 m and 1 km resolutions for a 5700 km2 watershed with an elevation range from 518 m to 3767 m in the Qinling Mountain, Shaanxi Province, China. Assuming that the NPP simulated at 30 m resolution represents the reality and that at 1 km resolution is subject to errors due to sub-pixel heterogeneity, a spatial scaling index (SSI) is developed to correct the coarse resolution NPP values pixel by pixel. The agreement between the NPP values at these two resolutions is improved considerably from R2 = 0.782 to R2 = 0.884 after the correction. The mean bias error (MBE) in NPP modeled at the 1 km resolution is reduced from 14.8 g C m-2 yr-1 to 4.8 g C m-2 yr-1 in comparison with NPP modeled at 30 m resolution, where the mean NPP is 668 g C m-2 yr-1. The range of spatial variations of NPP at 30 m resolution is larger than that at 1 km resolution. Land cover fraction is the most important vegetation factor to be considered in NPP spatial scaling, and slope is the most important topographical factor for NPP spatial scaling especially in mountainous areas, because of its influence on the lateral water redistribution, affecting water table, soil moisture and plant growth. Other factors including leaf area index (LAI), elevation and aspect have small and additive effects on improving the spatial scaling between these two resolutions.

  15. Effects of vegetation heterogeneity and surface topography on spatial scaling of net primary productivity

    NASA Astrophysics Data System (ADS)

    Chen, J. M.; Chen, X.; Ju, W.

    2013-07-01

    Due to the heterogeneous nature of the land surface, spatial scaling is an inevitable issue in the development of land models coupled with low-resolution Earth system models (ESMs) for predicting land-atmosphere interactions and carbon-climate feedbacks. In this study, a simple spatial scaling algorithm is developed to correct errors in net primary productivity (NPP) estimates made at a coarse spatial resolution based on sub-pixel information of vegetation heterogeneity and surface topography. An eco-hydrological model BEPS-TerrainLab, which considers both vegetation and topographical effects on the vertical and lateral water flows and the carbon cycle, is used to simulate NPP at 30 m and 1 km resolutions for a 5700 km2 watershed with an elevation range from 518 m to 3767 m in the Qinling Mountain, Shanxi Province, China. Assuming that the NPP simulated at 30 m resolution represents the reality and that at 1 km resolution is subject to errors due to sub-pixel heterogeneity, a spatial scaling index (SSI) is developed to correct the coarse resolution NPP values pixel by pixel. The agreement between the NPP values at these two resolutions is improved considerably from R2 = 0.782 to R2 = 0.884 after the correction. The mean bias error (MBE) in NPP modelled at the 1 km resolution is reduced from 14.8 g C m-2 yr-1 to 4.8 g C m-2 yr-1 in comparison with NPP modelled at 30 m resolution, where the mean NPP is 668 g C m-2 yr-1. The range of spatial variations of NPP at 30 m resolution is larger than that at 1 km resolution. Land cover fraction is the most important vegetation factor to be considered in NPP spatial scaling, and slope is the most important topographical factor for NPP spatial scaling especially in mountainous areas, because of its influence on the lateral water redistribution, affecting water table, soil moisture and plant growth. Other factors including leaf area index (LAI) and elevation have small and additive effects on improving the spatial scaling between these two resolutions.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Ke; Chen, Guang-Hong, E-mail: gchen7@wisc.edu; Garrett, John

    Purpose: Statistical model based iterative reconstruction (MBIR) methods have been introduced to clinical CT systems and are being used in some clinical diagnostic applications. The purpose of this paper is to experimentally assess the unique spatial resolution characteristics of this nonlinear reconstruction method and identify its potential impact on the detectabilities and the associated radiation dose levels for specific imaging tasks. Methods: The thoracic section of a pediatric phantom was repeatedly scanned 50 or 100 times using a 64-slice clinical CT scanner at four different dose levels [CTDI{sub vol} =4, 8, 12, 16 (mGy)]. Both filtered backprojection (FBP) and MBIRmore » (Veo{sup ®}, GE Healthcare, Waukesha, WI) were used for image reconstruction and results were compared with one another. Eight test objects in the phantom with contrast levels ranging from 13 to 1710 HU were used to assess spatial resolution. The axial spatial resolution was quantified with the point spread function (PSF), while the z resolution was quantified with the slice sensitivity profile. Both were measured locally on the test objects and in the image domain. The dependence of spatial resolution on contrast and dose levels was studied. The study also features a systematic investigation of the potential trade-off between spatial resolution and locally defined noise and their joint impact on the overall image quality, which was quantified by the image domain-based channelized Hotelling observer (CHO) detectability index d′. Results: (1) The axial spatial resolution of MBIR depends on both radiation dose level and image contrast level, whereas it is supposedly independent of these two factors in FBP. The axial spatial resolution of MBIR always improved with an increasing radiation dose level and/or contrast level. (2) The axial spatial resolution of MBIR became equivalent to that of FBP at some transitional contrast level, above which MBIR demonstrated superior spatial resolution than FBP (and vice versa); the value of this transitional contrast highly depended on the dose level. (3) The PSFs of MBIR could be approximated as Gaussian functions with reasonably good accuracy. (4) Thez resolution of MBIR showed similar contrast and dose dependence. (5) Noise standard deviation assessed on the edges of objects demonstrated a trade-off with spatial resolution in MBIR. (5) When both spatial resolution and image noise were considered using the CHO analysis, MBIR led to significant improvement in the overall CT image quality for both high and low contrast detection tasks at both standard and low dose levels. Conclusions: Due to the intrinsic nonlinearity of the MBIR method, many well-known CT spatial resolution and noise properties have been modified. In particular, dose dependence and contrast dependence have been introduced to the spatial resolution of CT images by MBIR. The method has also introduced some novel noise-resolution trade-off not seen in traditional CT images. While the benefits of MBIR regarding the overall image quality, as demonstrated in this work, are significant, the optimal use of this method in clinical practice demands a thorough understanding of its unique physical characteristics.« less

  17. High-resolution scanning precession electron diffraction: Alignment and spatial resolution.

    PubMed

    Barnard, Jonathan S; Johnstone, Duncan N; Midgley, Paul A

    2017-03-01

    Methods are presented for aligning the pivot point of a precessing electron probe in the scanning transmission electron microscope (STEM) and for assessing the spatial resolution in scanning precession electron diffraction (SPED) experiments. The alignment procedure is performed entirely in diffraction mode, minimising probe wander within the bright-field (BF) convergent beam electron diffraction (CBED) disk and is used to obtain high spatial resolution SPED maps. Through analysis of the power spectra of virtual bright-field images extracted from the SPED data, the precession-induced blur was measured as a function of precession angle. At low precession angles, SPED spatial resolution was limited by electronic noise in the scan coils; whereas at high precession angles SPED spatial resolution was limited by tilt-induced two-fold astigmatism caused by the positive spherical aberration of the probe-forming lens. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. Spatial resolution properties of motion-compensated tomographic image reconstruction methods.

    PubMed

    Chun, Se Young; Fessler, Jeffrey A

    2012-07-01

    Many motion-compensated image reconstruction (MCIR) methods have been proposed to correct for subject motion in medical imaging. MCIR methods incorporate motion models to improve image quality by reducing motion artifacts and noise. This paper analyzes the spatial resolution properties of MCIR methods and shows that nonrigid local motion can lead to nonuniform and anisotropic spatial resolution for conventional quadratic regularizers. This undesirable property is akin to the known effects of interactions between heteroscedastic log-likelihoods (e.g., Poisson likelihood) and quadratic regularizers. This effect may lead to quantification errors in small or narrow structures (such as small lesions or rings) of reconstructed images. This paper proposes novel spatial regularization design methods for three different MCIR methods that account for known nonrigid motion. We develop MCIR regularization designs that provide approximately uniform and isotropic spatial resolution and that match a user-specified target spatial resolution. Two-dimensional PET simulations demonstrate the performance and benefits of the proposed spatial regularization design methods.

  19. Development of a spatio-temporal disaggregation method (DisNDVI) for generating a time series of fine resolution NDVI images

    NASA Astrophysics Data System (ADS)

    Bindhu, V. M.; Narasimhan, B.

    2015-03-01

    Normalized Difference Vegetation Index (NDVI), a key parameter in understanding the vegetation dynamics, has high spatial and temporal variability. However, continuous monitoring of NDVI is not feasible at fine spatial resolution (<60 m) owing to the long revisit time needed by the satellites to acquire the fine spatial resolution data. Further, the study attains significance in the case of humid tropical regions of the earth, where the prevailing atmospheric conditions restrict availability of fine resolution cloud free images at a high temporal frequency. As an alternative to the lack of high resolution images, the current study demonstrates a novel disaggregation method (DisNDVI) which integrates the spatial information from a single fine resolution image and temporal information in terms of crop phenology from time series of coarse resolution images to generate estimates of NDVI at fine spatial and temporal resolution. The phenological variation of the pixels captured at the coarser scale provides the basis for relating the temporal variability of the pixel with the NDVI available at fine resolution. The proposed methodology was tested over a 30 km × 25 km spatially heterogeneous study area located in the south of Tamil Nadu, India. The robustness of the algorithm was assessed by an independent comparison of the disaggregated NDVI and observed NDVI obtained from concurrent Landsat ETM+ imagery. The results showed good spatial agreement across the study area dominated with agriculture and forest pixels, with a root mean square error of 0.05. The validation done at the coarser scale showed that disaggregated NDVI spatially averaged to 240 m compared well with concurrent MODIS NDVI at 240 m (R2 > 0.8). The validation results demonstrate the effectiveness of DisNDVI in improving the spatial and temporal resolution of NDVI images for utility in fine scale hydrological applications such as crop growth monitoring and estimation of evapotranspiration.

  20. How Attention Affects Spatial Resolution

    PubMed Central

    Carrasco, Marisa; Barbot, Antoine

    2015-01-01

    We summarize and discuss a series of psychophysical studies on the effects of spatial covert attention on spatial resolution, our ability to discriminate fine patterns. Heightened resolution is beneficial in most, but not all, visual tasks. We show how endogenous attention (voluntary, goal driven) and exogenous attention (involuntary, stimulus driven) affect performance on a variety of tasks mediated by spatial resolution, such as visual search, crowding, acuity, and texture segmentation. Exogenous attention is an automatic mechanism that increases resolution regardless of whether it helps or hinders performance. In contrast, endogenous attention flexibly adjusts resolution to optimize performance according to task demands. We illustrate how psychophysical studies can reveal the underlying mechanisms of these effects and allow us to draw linking hypotheses with known neurophysiological effects of attention. PMID:25948640

  1. Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue.

    PubMed

    Sakadzić, Sava; Roussakis, Emmanuel; Yaseen, Mohammad A; Mandeville, Emiri T; Srinivasan, Vivek J; Arai, Ken; Ruvinskaya, Svetlana; Devor, Anna; Lo, Eng H; Vinogradov, Sergei A; Boas, David A

    2010-09-01

    Measurements of oxygen partial pressure (pO(2)) with high temporal and spatial resolution in three dimensions is crucial for understanding oxygen delivery and consumption in normal and diseased brain. Among existing pO(2) measurement methods, phosphorescence quenching is optimally suited for the task. However, previous attempts to couple phosphorescence with two-photon laser scanning microscopy have faced substantial difficulties because of extremely low two-photon absorption cross-sections of conventional phosphorescent probes. Here we report to our knowledge the first practical in vivo two-photon high-resolution pO(2) measurements in small rodents' cortical microvasculature and tissue, made possible by combining an optimized imaging system with a two-photon-enhanced phosphorescent nanoprobe. The method features a measurement depth of up to 250 microm, sub-second temporal resolution and requires low probe concentration. The properties of the probe allowed for direct high-resolution measurement of cortical extravascular (tissue) pO(2), opening many possibilities for functional metabolic brain studies.

  2. Probing the electromagnetic field of a 15-nanometre hotspot by single molecule imaging.

    PubMed

    Cang, Hu; Labno, Anna; Lu, Changgui; Yin, Xiaobo; Liu, Ming; Gladden, Christopher; Liu, Yongmin; Zhang, Xiang

    2011-01-20

    When light illuminates a rough metallic surface, hotspots can appear, where the light is concentrated on the nanometre scale, producing an intense electromagnetic field. This phenomenon, called the surface enhancement effect, has a broad range of potential applications, such as the detection of weak chemical signals. Hotspots are believed to be associated with localized electromagnetic modes, caused by the randomness of the surface texture. Probing the electromagnetic field of the hotspots would offer much insight towards uncovering the mechanism generating the enhancement; however, it requires a spatial resolution of 1-2 nm, which has been a long-standing challenge in optics. The resolution of an optical microscope is limited to about half the wavelength of the incident light, approximately 200-300 nm. Although current state-of-the-art techniques, including near-field scanning optical microscopy, electron energy-loss spectroscopy, cathode luminescence imaging and two-photon photoemission imaging have subwavelength resolution, they either introduce a non-negligible amount of perturbation, complicating interpretation of the data, or operate only in a vacuum. As a result, after more than 30 years since the discovery of the surface enhancement effect, how the local field is distributed remains unknown. Here we present a technique that uses Brownian motion of single molecules to probe the local field. It enables two-dimensional imaging of the fluorescence enhancement profile of single hotspots on the surfaces of aluminium thin films and silver nanoparticle clusters, with accuracy down to 1.2 nm. Strong fluorescence enhancements, up to 54 and 136 times respectively, are observed in those two systems. This strong enhancement indicates that the local field, which decays exponentially from the peak of a hotspot, dominates the fluorescence enhancement profile.

  3. An assessment of SEVIRI imagery at different temporal resolutions and the effect on accurate dust emission mapping

    NASA Astrophysics Data System (ADS)

    Hennen, Mark; White, Kevin; Shahgedanova, Maria

    2017-04-01

    This paper compares Dust RGB products derived from the Spinning Enhanced Visible and Infrared Imager (SEVIRI) data at 15 minute, 30 minute and hourly temporal resolutions. From January 2006 to December 2006, observations of dust emission point sources were observed at each temporal resolution across the entire Middle East region (38.50N; 30.00E - 10.00N; 65.50E). Previous work has demonstrated that 15-minute resolution SEVIRI data can be used to map dust sources across the Sahara by observing dust storms back through sequential images to the point of first emission (Schepanski et al., 2007; 2009; 2012). These observations have improved upon lower resolution maps, based on daily retrievals of aerosol optical depth (AOD), whose maxima can be biased by prevalent transport routes, not necessarily coinciding with sources of emissions. Based on the thermal contrast of atmospheric dust to the surface, brightness temperature differences (BTD's) in the thermal infrared (TIR) wavelengths (8.7, 10.8 and 12.0 µm) highlight dust in the scene irrespective of solar illumination, giving both increased accuracy of dust source areas and a greater understanding of diurnal emission behaviour. However, the highest temporal resolution available (15-minute repeat capture) produces 96 images per day, resulting in significantly higher data storage demands than 30 minute or hourly data. To aid future research planning, this paper investigates what effect lowering the temporal resolution has on the number and spatial distribution of the observed dust sources. The results show a reduction in number of dust emission events observed with each step decrease in temporal resolution, reducing by 17% for 30-minute resolution and 50% for hourly. These differences change seasonally, with the highest reduction observed in summer (34% and 64% reduction respectively). Each resolution shows a similar spatial distribution, with the biggest difference seen near the coastlines, where near-shore convective cloud patterns obscure atmospheric dust soon after emission, restricting the opportunity to be observed at hourly resolution.

  4. Advances in Low-Temperature Tungsten Spectroscopy Capability to Quantify DIII-D Divertor Erosion

    DOE PAGES

    Abrams, Tyler; Thomas, Daniel M.; Unterberg, Ezekial A.; ...

    2018-01-05

    Recent emphasis of tungsten (W) plasma-materialsinteractions (PMI) experiments on DIII-D has made it essential to enhance the W I and W II measurement capabilities of its spectroscopy diagnostic suite to acquire W sourcing measurements with high temporal, spatial, and wavelength resolution. To this end, four new viewing chords for the Multichordal Divertor Spectrometer (MDS) and diverter filterscope systems were installed, leading to a 7x increase in blue light sensitivity. W I and low-Z impurity line identifications were performed in the 3995-4030 Å region, placing wavelengths within 0.1 Å of the NIST values. A novel method was also developed for themore » DIII-D high temporal resolution filterscopes to distinguish between W I light and background contamination, important due to the relatively weak intensity of this line, using two different bandpass filters width different widths but the same center wavelength. Lastly, fast imaging of the W I 4008.75 Å spectral line with a PCO Pixelfly VGA 200/205 camera allowed for discrimination between ELMy and intra-ELM W I emission profiles with very high (~1 mm) spatial resolution.« less

  5. Advances in Low-Temperature Tungsten Spectroscopy Capability to Quantify DIII-D Divertor Erosion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abrams, Tyler; Thomas, Daniel M.; Unterberg, Ezekial A.

    Recent emphasis of tungsten (W) plasma-materialsinteractions (PMI) experiments on DIII-D has made it essential to enhance the W I and W II measurement capabilities of its spectroscopy diagnostic suite to acquire W sourcing measurements with high temporal, spatial, and wavelength resolution. To this end, four new viewing chords for the Multichordal Divertor Spectrometer (MDS) and diverter filterscope systems were installed, leading to a 7x increase in blue light sensitivity. W I and low-Z impurity line identifications were performed in the 3995-4030 Å region, placing wavelengths within 0.1 Å of the NIST values. A novel method was also developed for themore » DIII-D high temporal resolution filterscopes to distinguish between W I light and background contamination, important due to the relatively weak intensity of this line, using two different bandpass filters width different widths but the same center wavelength. Lastly, fast imaging of the W I 4008.75 Å spectral line with a PCO Pixelfly VGA 200/205 camera allowed for discrimination between ELMy and intra-ELM W I emission profiles with very high (~1 mm) spatial resolution.« less

  6. Photoinduced force microscopy: A technique for hyperspectral nanochemical mapping

    NASA Astrophysics Data System (ADS)

    Murdick, Ryan A.; Morrison, William; Nowak, Derek; Albrecht, Thomas R.; Jahng, Junghoon; Park, Sung

    2017-08-01

    Advances in nanotechnology have intensified the need for tools that can characterize newly synthesized nanomaterials. A variety of techniques has recently been shown which combines atomic force microscopy (AFM) with optical illumination including tip-enhanced Raman spectroscopy (TERS), scattering-type scanning near-field optical microscopy (sSNOM), and photothermal induced resonance microscopy (PTIR). To varying degrees, these existing techniques enable optical spectroscopy with the nanoscale spatial resolution inherent to AFM, thereby providing nanochemical interrogation of a specimen. Here we discuss photoinduced force microscopy (PiFM), a recently developed technique for nanoscale optical spectroscopy that exploits image forces acting between an AFM tip and sample to detect wavelength-dependent polarization within the sample to generate absorption spectra. This approach enables ∼10 nm spatial resolution with spectra that show correlation with macroscopic optical absorption spectra. Unlike other techniques, PiFM achieves this high resolution with virtually no constraints on sample or substrate properties. The applicability of PiFM to a variety of archetypal systems is reported here, highlighting the potential of PiFM as a useful tool for a wide variety of industrial and academic investigations, including semiconducting nanoparticles, nanocellulose, block copolymers, and low dimensional systems, as well as chemical and morphological mixing at interfaces.

  7. Super-resolution optical microscopy for studying membrane structure and dynamics.

    PubMed

    Sezgin, Erdinc

    2017-07-12

    Investigation of cell membrane structure and dynamics requires high spatial and temporal resolution. The spatial resolution of conventional light microscopy is limited due to the diffraction of light. However, recent developments in microscopy enabled us to access the nano-scale regime spatially, thus to elucidate the nanoscopic structures in the cellular membranes. In this review, we will explain the resolution limit, address the working principles of the most commonly used super-resolution microscopy techniques and summarise their recent applications in the biomembrane field.

  8. Multishot Targeted PROPELLER Magnetic Resonance Imaging: Description of the Technique and Initial Applications

    PubMed Central

    Deng, Jie; Larson, Andrew C.

    2010-01-01

    Objectives To test the feasibility of combining inner-volume imaging (IVI) techniques with conventional multishot periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) techniques for targeted-PROPELLER magnetic resonance imaging. Materials and Methods Perpendicular section-selective gradients for spatially selective excitation and refocusing RF pulses were applied to limit the refocused field-of-view (FOV) along the phase-encoding direction for each rectangular blade image. We performed comparison studies in phantoms and normal volunteers by using targeted-PROPELLER methods for a wide range of imaging applications that commonly use turbo-spin-echo (TSE) approaches (brain, abdominal, vessel wall, cardiac). Results In these initial studies, we demonstrated the feasibility of using targeted-PROPELLER approaches to limit the imaging FOV thereby reducing the number of blades or permitting increased spatial resolution without commensurate increases in scan time. Both phantom and in vivo motion studies demonstrated the potential for more robust regional self-navigated motion correction compared with conventional full FOV PROPELLER methods. Conclusion We demonstrated that the reduced FOV targeted-PROPELLER technique offers the potential for reducing imaging time, increasing spatial resolution, and targeting specific areas for robust regional motion correction. PMID:19465860

  9. Comparison of alternative spatial resolutions in the application of a spatially distributed biogeochemical model over complex terrain

    USGS Publications Warehouse

    Turner, D.P.; Dodson, R.; Marks, D.

    1996-01-01

    Spatially distributed biogeochemical models may be applied over grids at a range of spatial resolutions, however, evaluation of potential errors and loss of information at relatively coarse resolutions is rare. In this study, a georeferenced database at the 1-km spatial resolution was developed to initialize and drive a process-based model (Forest-BGC) of water and carbon balance over a gridded 54976 km2 area covering two river basins in mountainous western Oregon. Corresponding data sets were also prepared at 10-km and 50-km spatial resolutions using commonly employed aggregation schemes. Estimates were made at each grid cell for climate variables including daily solar radiation, air temperature, humidity, and precipitation. The topographic structure, water holding capacity, vegetation type and leaf area index were likewise estimated for initial conditions. The daily time series for the climatic drivers was developed from interpolations of meteorological station data for the water year 1990 (1 October 1989-30 September 1990). Model outputs at the 1-km resolution showed good agreement with observed patterns in runoff and productivity. The ranges for model inputs at the 10-km and 50-km resolutions tended to contract because of the smoothed topography. Estimates for mean evapotranspiration and runoff were relatively insensitive to changing the spatial resolution of the grid whereas estimates of mean annual net primary production varied by 11%. The designation of a vegetation type and leaf area at the 50-km resolution often subsumed significant heterogeneity in vegetation, and this factor accounted for much of the difference in the mean values for the carbon flux variables. Although area wide means for model outputs were generally similar across resolutions, difference maps often revealed large areas of disagreement. Relatively high spatial resolution analyses of biogeochemical cycling are desirable from several perspectives and may be particularly important in the study of the potential impacts of climate change.

  10. The fusion of satellite and UAV data: simulation of high spatial resolution band

    NASA Astrophysics Data System (ADS)

    Jenerowicz, Agnieszka; Siok, Katarzyna; Woroszkiewicz, Malgorzata; Orych, Agata

    2017-10-01

    Remote sensing techniques used in the precision agriculture and farming that apply imagery data obtained with sensors mounted on UAV platforms became more popular in the last few years due to the availability of low- cost UAV platforms and low- cost sensors. Data obtained from low altitudes with low- cost sensors can be characterised by high spatial and radiometric resolution but quite low spectral resolution, therefore the application of imagery data obtained with such technology is quite limited and can be used only for the basic land cover classification. To enrich the spectral resolution of imagery data acquired with low- cost sensors from low altitudes, the authors proposed the fusion of RGB data obtained with UAV platform with multispectral satellite imagery. The fusion is based on the pansharpening process, that aims to integrate the spatial details of the high-resolution panchromatic image with the spectral information of lower resolution multispectral or hyperspectral imagery to obtain multispectral or hyperspectral images with high spatial resolution. The key of pansharpening is to properly estimate the missing spatial details of multispectral images while preserving their spectral properties. In the research, the authors presented the fusion of RGB images (with high spatial resolution) obtained with sensors mounted on low- cost UAV platforms and multispectral satellite imagery with satellite sensors, i.e. Landsat 8 OLI. To perform the fusion of UAV data with satellite imagery, the simulation of the panchromatic bands from RGB data based on the spectral channels linear combination, was conducted. Next, for simulated bands and multispectral satellite images, the Gram-Schmidt pansharpening method was applied. As a result of the fusion, the authors obtained several multispectral images with very high spatial resolution and then analysed the spatial and spectral accuracies of processed images.

  11. Large-watershed flood simulation and forecasting based on different-resolution distributed hydrological model

    NASA Astrophysics Data System (ADS)

    Li, J.

    2017-12-01

    Large-watershed flood simulation and forecasting is very important for a distributed hydrological model in the application. There are some challenges including the model's spatial resolution effect, model performance and accuracy and so on. To cope with the challenge of the model's spatial resolution effect, different model resolution including 1000m*1000m, 600m*600m, 500m*500m, 400m*400m, 200m*200m were used to build the distributed hydrological model—Liuxihe model respectively. The purpose is to find which one is the best resolution for Liuxihe model in Large-watershed flood simulation and forecasting. This study sets up a physically based distributed hydrological model for flood forecasting of the Liujiang River basin in south China. Terrain data digital elevation model (DEM), soil type and land use type are downloaded from the website freely. The model parameters are optimized by using an improved Particle Swarm Optimization(PSO) algorithm; And parameter optimization could reduce the parameter uncertainty that exists for physically deriving model parameters. The different model resolution (200m*200m—1000m*1000m ) are proposed for modeling the Liujiang River basin flood with the Liuxihe model in this study. The best model's spatial resolution effect for flood simulation and forecasting is 200m*200m.And with the model's spatial resolution reduction, the model performance and accuracy also become worse and worse. When the model resolution is 1000m*1000m, the flood simulation and forecasting result is the worst, also the river channel divided based on this resolution is differs from the actual one. To keep the model with an acceptable performance, minimum model spatial resolution is needed. The suggested threshold model spatial resolution for modeling the Liujiang River basin flood is a 500m*500m grid cell, but the model spatial resolution with a 200m*200m grid cell is recommended in this study to keep the model at a best performance.

  12. Analysis of the impact of spatial resolution on land/water classifications using high-resolution aerial imagery

    USGS Publications Warehouse

    Enwright, Nicholas M.; Jones, William R.; Garber, Adrienne L.; Keller, Matthew J.

    2014-01-01

    Long-term monitoring efforts often use remote sensing to track trends in habitat or landscape conditions over time. To most appropriately compare observations over time, long-term monitoring efforts strive for consistency in methods. Thus, advances and changes in technology over time can present a challenge. For instance, modern camera technology has led to an increasing availability of very high-resolution imagery (i.e. submetre and metre) and a shift from analogue to digital photography. While numerous studies have shown that image resolution can impact the accuracy of classifications, most of these studies have focused on the impacts of comparing spatial resolution changes greater than 2 m. Thus, a knowledge gap exists on the impacts of minor changes in spatial resolution (i.e. submetre to about 1.5 m) in very high-resolution aerial imagery (i.e. 2 m resolution or less). This study compared the impact of spatial resolution on land/water classifications of an area dominated by coastal marsh vegetation in Louisiana, USA, using 1:12,000 scale colour-infrared analogue aerial photography (AAP) scanned at four different dot-per-inch resolutions simulating ground sample distances (GSDs) of 0.33, 0.54, 1, and 2 m. Analysis of the impact of spatial resolution on land/water classifications was conducted by exploring various spatial aspects of the classifications including density of waterbodies and frequency distributions in waterbody sizes. This study found that a small-magnitude change (1–1.5 m) in spatial resolution had little to no impact on the amount of water classified (i.e. percentage mapped was less than 1.5%), but had a significant impact on the mapping of very small waterbodies (i.e. waterbodies ≤ 250 m2). These findings should interest those using temporal image classifications derived from very high-resolution aerial photography as a component of long-term monitoring programs.

  13. Polymeric spatial resolution test patterns for mass spectrometry imaging using nano-thermal analysis with atomic force microscopy

    DOE PAGES

    Tai, Tamin; Kertesz, Vilmos; Lin, Ming -Wei; ...

    2017-05-11

    As the spatial resolution of mass spectrometry imaging technologies has begun to reach into the nanometer regime, finding readily available or easily made resolution reference materials has become particularly challenging for molecular imaging purposes. This study describes the fabrication, characterization and use of vertical line array polymeric spatial resolution test patterns for nano-thermal analysis/atomic force microscopy/mass spectrometry chemical imaging.

  14. Polymeric spatial resolution test patterns for mass spectrometry imaging using nano-thermal analysis with atomic force microscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tai, Tamin; Kertesz, Vilmos; Lin, Ming -Wei

    As the spatial resolution of mass spectrometry imaging technologies has begun to reach into the nanometer regime, finding readily available or easily made resolution reference materials has become particularly challenging for molecular imaging purposes. This study describes the fabrication, characterization and use of vertical line array polymeric spatial resolution test patterns for nano-thermal analysis/atomic force microscopy/mass spectrometry chemical imaging.

  15. Real-time sound speed correction using golden section search to enhance ultrasound imaging quality

    NASA Astrophysics Data System (ADS)

    Yoon, Chong Ook; Yoon, Changhan; Yoo, Yangmo; Song, Tai-Kyong; Chang, Jin Ho

    2013-03-01

    In medical ultrasound imaging, high-performance beamforming is important to enhance spatial and contrast resolutions. A modern receive dynamic beamfomer uses a constant sound speed that is typically assumed to 1540 m/s in generating receive focusing delays [1], [2]. However, this assumption leads to degradation of spatial and contrast resolutions particularly when imaging obese patients or breast since the sound speed is significantly lower than the assumed sound speed [3]; the true sound speed in the fatty tissue is around 1450 m/s. In our previous study, it was demonstrated that the modified nonlinear anisotropic diffusion is capable of determining an optimal sound speed and the proposed method is a useful tool to improve ultrasound image quality [4], [5]. In the previous study, however, we utilized at least 21 iterations to find an optimal sound speed, which may not be viable for real-time applications. In this paper, we demonstrates that the number of iterations can be dramatically reduced using the GSS(golden section search) method with a minimal error. To evaluate performances of the proposed method, in vitro experiments were conducted with a tissue mimicking phantom. To emulate a heterogeneous medium, the phantom was immersed in the water. From the experiments, the number of iterations was reduced from 21 to 7 with GSS method and the maximum error of the lateral resolution between direct and GSS was less than 1%. These results indicate that the proposed method can be implemented in real time to improve the image quality in the medical ultrasound imaging.

  16. Data-driven signal-resolving approaches of infrared spectra to explore the macroscopic and microscopic spatial distribution of organic and inorganic compounds in plant.

    PubMed

    Chen, Jian-bo; Sun, Su-qin; Zhou, Qun

    2015-07-01

    The nondestructive and label-free infrared (IR) spectroscopy is a direct tool to characterize the spatial distribution of organic and inorganic compounds in plant. Since plant samples are usually complex mixtures, signal-resolving methods are necessary to find the spectral features of compounds of interest in the signal-overlapped IR spectra. In this research, two approaches using existing data-driven signal-resolving methods are proposed to interpret the IR spectra of plant samples. If the number of spectra is small, "tri-step identification" can enhance the spectral resolution to separate and identify the overlapped bands. First, the envelope bands of the original spectrum are interpreted according to the spectra-structure correlations. Then the spectrum is differentiated to resolve the underlying peaks in each envelope band. Finally, two-dimensional correlation spectroscopy is used to enhance the spectral resolution further. For a large number of spectra, "tri-step decomposition" can resolve the spectra by multivariate methods to obtain the structural and semi-quantitative information about the chemical components. Principal component analysis is used first to explore the existing signal types without any prior knowledge. Then the spectra are decomposed by self-modeling curve resolution methods to estimate the spectra and contents of significant chemical components. At last, targeted methods such as partial least squares target can explore the content profiles of specific components sensitively. As an example, the macroscopic and microscopic distribution of eugenol and calcium oxalate in the bud of clove is studied.

  17. Strain measurement using a Brillouin optical time domain reflectometer for development of aircraft structure health monitoring system

    NASA Astrophysics Data System (ADS)

    Shimizu, Takayuki; Yari, Takashi; Nagai, Kanehiro; Takeda, Nobuo

    2001-07-01

    We conducted theoretical and experimental approaches for applying Brillouin optical time domain reflectometer (BOTDR) to aircraft and spacecraft structure health monitoring system. Firstly, distributed strain was measured by BOTDR under 3-point bending test and a spatial resolution was enhanced up to 0.5m using Brillouin spectrum analysis and processing though the device used in this experiment had a spatial resolution of 2m normally. Secondly, dynamic strain measurement was executed under cyclic loading conditions. Brillouin spectrum measured under dynamic conditions is equivalent to superposed spectrum using many spectra measured under static loading conditions. As the measured spectrum was decomposed into many spectra in static loading state, the strain amplitude and its ratio could be estimated. Thirdly, strain and temperature could be measured independently using combined system of BOTDR and fiber Bragg grating (FBG) with wavelength division multiplexing (WDM). Additionally, the application of BOTDR sensing system was shown for a prototype carbon fiber reinforced plastic (CFRP) liquid hydrogen (LH2) tank under cryogenic condition.

  18. Spatial resolution enhancement of satellite image data using fusion approach

    NASA Astrophysics Data System (ADS)

    Lestiana, H.; Sukristiyanti

    2018-02-01

    Object identification using remote sensing data has a problem when the spatial resolution is not in accordance with the object. The fusion approach is one of methods to solve the problem, to improve the object recognition and to increase the objects information by combining data from multiple sensors. The application of fusion image can be used to estimate the environmental component that is needed to monitor in multiple views, such as evapotranspiration estimation, 3D ground-based characterisation, smart city application, urban environments, terrestrial mapping, and water vegetation. Based on fusion application method, the visible object in land area has been easily recognized using the method. The variety of object information in land area has increased the variation of environmental component estimation. The difficulties in recognizing the invisible object like Submarine Groundwater Discharge (SGD), especially in tropical area, might be decreased by the fusion method. The less variation of the object in the sea surface temperature is a challenge to be solved.

  19. The Extended Range X-Ray Telescope center director's discretionary fund report

    NASA Technical Reports Server (NTRS)

    Hoover, R. B.; Cumings, N. P.; Hildner, E.; Moore, R. L.; Tandberg-Hanssen, E. A.

    1985-01-01

    An Extended Range X-Ray Telescope (ERXRT) of high sensitivity and spatial resolution capable of functioning over a broad region of the X-ray/XUV portion of the spectrum has been designed and analyzed. This system has been configured around the glancing-incidence Wolter Type I X-ray mirror system which was flown on the Skylab Apollo Telescope Mount as ATM Experiment S-056. Enhanced sensitivity over a vastly broader spectral range can be realized by the utilization of a thinned, back-illuminated, buried-channel Charge Coupled Device (CCD) as the X-ray/XUV detector rather than photographic film. However, to maintain the high spatial resolution inherent in the X-ray optics when a CCD of 30 micron pixel size is used, it is necessary to increase the telescope plate scale. This can be accomplished by use of a glancing-incidence X-ray microscope to enlarge and re-focus the primary image onto the focal surface of the CCD.

  20. The GKSS beamlines at PETRA III and DORIS III

    NASA Astrophysics Data System (ADS)

    Haibel, A.; Beckmann, F.; Dose, T.; Herzen, J.; Utcke, S.; Lippmann, T.; Schell, N.; Schreyer, A.

    2008-08-01

    Due to the high brilliance of the new storage ring PETRA III at DESY in Hamburg, the low emittance of 1 nmrad and the high fraction of coherent photons also in the hard X-ray range extremely intense and sharply focused X-ray light will be provided. These advantages of the beam fulfill excellently the qualifications for the planned Imaging BeamLine IBL and the High Energy Materials Science Beamline (HEMS) at PETRA III, i.e. for absorption tomography, phase enhanced and phase contrast experiments, for diffraction, for nano focusing, for nano tomography, and for high speed or in-situ experiments with highest spatial resolution. The existing HARWI II beamline at the DORIS III storage ring at DESY completes the GKSS beamline concept with setups for high energy tomography (16-150 keV) and diffraction (16-250 keV), characterized by a large field of view and an excellent absorption contrast with spatial resolutions down to 2 μm.

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