enhanced density sed: Topics by Science.gov

Sample records for enhanced density sed

Multi-instrument Observations of Storm Enhanced Density (SED) During the Oct. 24-25 2011 Storm: Implications for SED Formation Processes (Invited)

NASA Astrophysics Data System (ADS)

Zou, S.; Ridley, A. J.; Moldwin, M.; Nicolls, M. J.; Coster, A. J.; Thomas, E. G.; Ruohoniemi, J.

2013-12-01

Ionospheric density often exhibits significant variations, which affect the propagation of radio signals that pass through or are reflected by the ionosphere. One example of these effects is the loss of phase lock and range errors in Global Navigation Satellite Systems (GNSS) signals. Because our modern society increasingly relies on ground-to-ground and ground-to-space communications and navigation, understanding the sources of the ionospheric density variability and monitoring its dynamics during space weather events has great importance. Storm-enhanced density (SED) is one of the most prominent ionospheric density structures that can have significant space weather impact. We present multi-instrument observations of a SED event during the Oct. 24-25, 2011 intense geomagnetic storm. Formation and the subsequent evolution of the SED and the mid-latitude trough are revealed by global GPS vertical total electron content (VTEC) maps. In addition, we present high time resolution Poker Flat Incoherent Scatter Radar (PFISR) observations of ionospheric properties within the SED. The SED structure observed by PFISR is found to consist of two parts with different properties. Both parts are characterized by elevated ionospheric peak height (HmF2) and TEC, compared to quiet time values. However, the two parts of the SED have different characteristics in the electron temperature (Te), the F-region peak density (NmF2) and convection flows. The first part of the SED is associated with enhanced Te in the lower F region and reduced Te in the upper F region, and is collocated with northward convection flows. The NmF2 was lower than quiet time values. The second part of the SED is associated with significantly increased NmF2, elevated Te at all altitudes, and is located near the equatorward boundary of large northwestward flow, which is probably subauroral polarization stream (SAPS). Based on these observations, we suggest that the mechanisms responsible for the formation of the two parts of the SED are different. The first part is due to equatorward expansion of the convection pattern and the projection of northward convection flows in the vertical direction, which lifts the ionospheric plasma to higher altitudes and thus reduces the loss rate of plasma recombination. The formation mechanism of the second part appears more complex. Besides equatorward expansion of the convection pattern and large upward flows, evidence of other mechanisms, including horizontal advection due to SAPS flows, energetic particle precipitation, and enhanced thermospheric wind in the topside ionosphere, is also present in the observations. Our estimates show that contribution from precipitating energetic protons accounts for at most ~10% of the total F-region density. The thermospheric wind also plays a minor role in this case.
Great Lakes Region Morphology and Impacts of March 17, 2015 SED Geomagnetic Storm

NASA Astrophysics Data System (ADS)

Heine, T.; Moldwin, M.; Zou, S.

2015-12-01

Under quiet geomagnetic conditions, the mid-latitude ionosphere is relatively uniform with little spatial variation in electron density. However, during intense geomagnetic storms, density gradients associated with Storm Enhanced Density (SED) plumes and Sub-auroral Polarization Streams (SAPS) can move across the dayside mid-latitude ionosphere producing small spatial scale density structure that may be connected to ionospheric scintillation. The evolution of the SED plume during the March 17, 2015 "St. Patrick's Day Storm" is investigated using aggregated data from high resolution GPS receivers at the University of Michigan and throughout the Great Lakes region. Structural density features in the SED gradient can be observed and compared to GPS scintillation measurements—providing insight into the physical mechanisms behind ionospheric scintillation.
Observations of subauroral ionospheric dynamics during SED plume passage at Millstone Hill

NASA Astrophysics Data System (ADS)

Zhang, S.; Erickson, P. J.; Coster, A. J.

2017-12-01

Storm enhanced density (SED) is a characteristic ionospheric storm time structure, with a significant plasma density enhancement in a narrow zone. SED structures often (but not always) span the continental US with a base in the US northeast at the afternoon and dusk sector, extending westward or northwest into the high latitude dayside cusp region. It is a typical and repeatable space weather phenomenon occurring during the main phase of magnetic storms with intensity ranging from active to disturbed levels. Observations of stormtime ionospheric density enhancement at subauroral latitudes have a long history, and were termed the 'dusk effect' until relatively recently, when dense networks of GNSS receivers have allowed us to view this structure with much finer spatial and temporal resolution. The formation of a SED plume is a topic under intensive community investigation, but in general it is believed that stormtime ionospheric dynamics and processes within the coupling magnetosphere-ionosphere-thermosphere system are responsible. For instance, poleward and sunward plasma drifts at the edge of the expanded dusk sector high-latitude convection can be important. Subauroral polarization stream (SAPS) are often observed at the poleward edge of the SED plume where ionospheric conductivity is low. SAPS is a huge westward ion flow that can convect ionospheric plasma from the afternoon or evening sector where solar photoionization production is waning, creating low density or density troughs. Stormtime penetration electric fields also exist, creating enhanced low and mid latitude upward ion drifts that move ionospheric plasma upward from the low altitude region where they are produced. This provides another important ionization source to contribute to maintaining the SED plume. This paper will provide analysis of the relative strength of these factors by using joint datasets of current geospace storm events obtained with the Millstone Hill incoherent scatter radar, GNSS TEC maps, and DMSP in situ measurements.
Investigating Perturbation Electric Fields and Their Effects on the Coupled Low-, Mid- and High-latitude Ionosphere

DTIC Science & Technology

2015-08-14

stream (SAPS) E field had been strong. During these E field events, the repeated development of equatorial ionization anomaly ( EIA ), storm-enhanced...density (SED) bulge and SED plume occurred in those longitude sectors that covered the local dusk-midnight hours. Thus, a well-formed EIA - SED...Observational results and CTIPe simulated wind vector maps suggest that 1) the enhanced growth of the EIA transported solar produced plasma to the
Dynamic Fluid-Kinetic (DyFK) Simulations of Storm-Enhanced Density Supply of Cleft Ion Fountain Outflows

NASA Astrophysics Data System (ADS)

Horwitz, J. L.; Zeng, W.; Foster, J. C.; Strangeway, R. J.; Adrian, M. L.; Moore, T. E.

2008-12-01

Elevated ionospheric density regions frequently appear to be convected from the subauroral plasmaspheric region toward noon, in association with convection of plasmaspheric tails in the dayside magnetosphere, typically during large geomagnetic storms. In this presentation, we explore the possibility that these Storm Enhanced Density (SED) regions could provide ionospheric plasma source populations for cleft ion fountain outflows. We use our Dynamic Fluid Kinetic (DyFK) code to simulate the entry of a high-density "plasmasphere-like" flux tube entering the cleft region and subjected to an episode of wave-driven transverse ion heating. The results of including different proportions of SED and soft electron precipitation levels, together with transverse ion heating effects on the resulting outflows, will be presented, including the O+ and H+ ion density and related parameter profiles for the simulated SED involved events. We will also compare these modeling results with SED-outflow observations from GPS TEC, and the FAST and IMAGE spacecraft. Foster, J. C., P. J. Erickson, A. J. Coster, J. Goldstein, and F. J. Rich, Ionospheric signatures of plasmaspheric tails, Geophys. Res. Lett., 29(13), 1623, doi:10.1029/2002GL015067, 2002.
Storm Enhanced Density (SED) plumes as possible suppliers of dayside cleft ion fountain

NASA Astrophysics Data System (ADS)

Horwitz, James

Foster et al. [2002] have observed elevated ionospheric density regions being convected from the subauroral plasmaspheric region toward noon, in association with convection of plasmaspheric tails in the dayside magnetosphere. These so-called Storm Enhanced Density (SED) regions could serve as ionospheric plasma source populations for cleft ion fountain outflows. Here we examine this scenario and employ our fluid-kinetic ionospheric plasma transport code to simulate the entry of a high-density "plasmasphere-like" flux tube entering the cleft region and subjected to an episode of wave-driven transverse ion heating. We find that such pronounced intervals of SED at F-region and topside altitudes passing through regions of CIF processes indeed appear capable of supporting episodes of strong CIF outflows. Foster, J. C., P. J. Erickson, A. J. Coster, J. Goldstein, and F. J. Rich, Ionospheric signatures of plasmaspheric tails, Geophys. Res. Lett., 29(13), 1623, doi:10.1029/2002GL015067, 2002.
Profiles of Ionospheric Storm-enhanced Density during the 17 March 2015 Great Storm

NASA Astrophysics Data System (ADS)

Liu, J.; Wang, W.; Burns, A. G.; Yue, X.; Zhang, S.; Zhang, Y.

2015-12-01

Ionospheric F2 region peak densities (NmF2) are expected to show a positive phase correlation with total electron content (TEC), and electron density is expected to have an anti-correlation with electron temperature near the ionospheric F2 peak. However, we show that, during the 17 March 2015 great storm, TEC and F2 region electron density peak height (hmF2) over Millstone Hill increased, but the F2 region electron density peak (NmF2) decreased significantly during the storm-enhanced density (SED) phase of the storm compared with the quiet-time ionosphere. This SED occurred where there was a negative ionospheric storm near the F2 peak and below it. The weak ionosphere below the F2 peak resulted in much reduced downward heat conduction for the electrons, trapping the heat in the topside. This, in turn, increased the topside scale height, so that, even though electron densities at the F2 peak were depleted, TEC increased in the SED. The depletion in NmF2 was probably caused by an increase in the density of the molecular neutrals, resulting in enhanced recombination. In addition, the storm-time topside ionospheric electron density profile was much closer to diffusive equilibrium than non-storm time profile because of less daytime plasma flow from the ionosphere to the plasmasphere.
Relative importance of horizontal and vertical transports to the formation of ionospheric storm-enhanced density and polar tongue of ionization

NASA Astrophysics Data System (ADS)

Liu, Jing; Wang, Wenbin; Burns, Alan; Solomon, Stanley C.; Zhang, Shunrong; Zhang, Yongliang; Huang, Chaosong

2016-08-01

There are still uncertainties regarding the formation mechanisms for storm-enhanced density (SED) in the high and subauroral latitude ionosphere. In this work, we deploy the Thermosphere Ionosphere Electrodynamic General Circulation Model (TIEGCM) and GPS total electron content (TEC) observations to identify the principle mechanisms for SED and the tongue of ionization (TOI) through term-by-term analysis of the ion continuity equation and also identify the advantages and deficiencies of the TIEGCM in capturing high-latitude and subauroral latitude ionospheric fine structures for the two geomagnetic storm events occurring on 17 March 2013 and 2015. Our results show that in the topside ionosphere, upward E × B ion drifts are most important in SED formation and are offset by antisunward neutral winds and downward ambipolar diffusion effects. In the bottomside F region ionosphere, neutral winds play a major role in generating SEDs. SED signature in TEC is mainly caused by upward E × B ion drifts that lift the ionosphere to higher altitudes where chemical recombination is slower. Horizontal E × B ion drifts play an essential role in transporting plasma from the dayside convection throat region to the polar cap to form TOIs. Inconsistencies between model results and GPS TEC data were found: (1) GPS relative TEC difference between storm time and quiet time has "holes" in the dayside ion convection entrance region, which do not appear in the model results. (2) The model tends to overestimate electron density enhancements in the polar region. Possible causes for these inconsistencies are discussed in this article.
Small-scale structure of the midlatitude storm enhanced density plume during the 17 March 2015 St. Patrick's Day storm

NASA Astrophysics Data System (ADS)

Heine, Thomas R. P.; Moldwin, Mark B.; Zou, Shasha

2017-03-01

Kilometer-scale density irregularities in the ionosphere can cause ionospheric scintillation—a phenomenon that degrades space-based navigation and communication signals. During strong geomagnetic storms, the midlatitude ionosphere is primed to produce these ˜1-10 km small-scale irregularities along the steep gradients between midlatitude storm enhanced density (SED) plumes and the adjacent low-density trough. The length scales of irregularities on the order of 1-10 km are determined from a combination of spatial, temporal, and frequency analyses using single-station ground-based Global Positioning System total electron content (TEC) combined with radar plasma velocity measurements. Kilometer-scale irregularities are detected along the boundaries of the SED plume and depleted density trough during the 17 March 2015 geomagnetic storm, but not equatorward of the plume or within the plume itself. Analysis using the fast Fourier transform of high-pass filtered slant TEC suggests that the kilometer-scale irregularities formed near the poleward gradients of SED plumes can have similar intensity and length scales to those typically found in the aurora but are shown to be distinct phenomena in spacecraft electron precipitation measurements.
Simulations of the Cleft Ion Fountain outflows resulting from the passage of Storm Enhanced Density (SED) plasma flux tubes through the dayside cleft auroral processes region

NASA Astrophysics Data System (ADS)

Horwitz, James; Zeng, Wen

2007-10-01

Foster et al. [2002] reported elevated ionospheric density regions convected from subauroral plasmaspheric regions toward noon, in association with convection of plasmaspheric tails. These Storm Enhanced Density (SED) regions could supply cleft ion fountain outflows. Here, we will utilize our Dynamic Fluid Kinetic (DyFK) model to simulate the entry of a high-density ``plasmasphere-like'' flux tube entering the cleft region and subjected to an episode of wave-driven transverse ion heating. It is found that the O^+ ion density at higher altitudes increases and the density at lower altitudes decreases, following this heating episode, indicating increased fluxes of O^+ ions from the ionospheric source gain sufficient energy to reach higher altitudes after the effects of transverse wave heating. Foster, J. C., P. J. Erickson, A. J. Coster, J. Goldstein, and F. J. Rich, Ionospheric signatures of plasmaspheric tails, Geophys. Res. Lett., 29(13), 1623, doi:10.1029/2002GL015067, 2002.
Multiple Magnetic Storm Study of the High-Altitude Redistribution of Equatorial Plasma

NASA Astrophysics Data System (ADS)

Bust, G. S.; Crowley, G.; Curtis, N.; Anderson, D.

2008-12-01

During geomagnetic storms, particularly when prompt penetration electric fields (PPE) occur, the equatorial plasma can be lifted to very high altitudes and then diffuse along magnetic field lines to higher than normal latitudes. During these cases very high plasma density (total electron content (TEC) greater than 200 TECU) can be found at these higher latitudes. Shortly after the PPE lifts the equatorial plasma to higher altitudes, at least in the US sector, phenomena known as storm-enhanced density (SED) can occur. SEDs occur in the post-noon time frame and consist of a very high density bulge that seems to occur in the southern USA and Caribbean region, followed by a narrow plume of high density plasma that flows into the high-latitude throat near local noon, and across the polar cap. An outstanding research question is: Exactly how is the high density SED plasma, particularly in the bulge related to the PPE and lifting of the equatorial plasma? Ionospheric imaging of electron density and TEC seem to show a gap in density between the poleward extent of the equatorial plasma and the equatorial extent of the SED plasma. Further, there are magnetic storm events where SEDs do not form (November 2004 as a good example). This paper will investigate the relationship between the equatorial high altitude plasma distribution during magnetic storms, and the initiation and evolution of the SED feature. We will examine eight separate storms from 2003-2006 using the ionospheric data assimilation algorithm IDA4D. In particular we will focus on time periods when LEO satellite GPS TEC data is available from CHAMP, SACC, GRACE and the COSMIC constellation (2006 and beyond). These data sets directly measure the TEC above the satellites, and therefore are good tracers of the high altitude plasma distribution. IDA4D ingests these data sets and uses them to get an improved image of the plasma density for the topside ionosphere and plasmasphere. The resulting 4D images of high altitude densities will be cross compared for the various storms and the similarities and differences will be studied and correlated with various geophysical parameters such as the interplanetary magnetic field (Bz), Dst, hemispheric power, cross cap potential, PPE, equatorial vertical drifts, and the interplanetary electric field. The overall objective is to elucidate the physical relationships that govern the redistribution of equatorial plasma during storms, and the generation and evolution of SEDs.
Sprint training shortens prolonged action potential duration in postinfarction rat myocyte: mechanisms.

PubMed

Zhang, X Q; Zhang, L Q; Palmer, B M; Ng, Y C; Musch, T I; Moore, R L; Cheung, J Y

2001-05-01

Two electrophysiological manifestations of myocardial infarction (MI)-induced myocyte hypertrophy are prolongation of action potential duration (APD) and reduction of transient outward current (I(to)) density. Because high-intensity sprint training (HIST) ameliorated myocyte hypertrophy and improved myocyte Ca(2+) homeostasis and contractility after MI, the present study evaluated whether 6-8 wk of HIST would shorten the prolonged APD and improve the depressed I(to) in post-MI myocytes. There were no differences in resting membrane potential and action potential amplitude (APA) measured in myocytes isolated from sham-sedentary (Sed), MI-Sed, and MI-HIST groups. Times required for repolarization to 50 and 90% APA were significantly (P < 0.001) prolonged in MI-Sed myocytes. HIST reduced times required for repolarization to 50 and 90% APA to values observed in Sham-Sed myocytes. The fast and slow components of I(to) were significantly (P < 0.0001) reduced in MI-Sed myocytes. HIST significantly (P < 0.001) enhanced the fast and slow components of I(to) in MI myocytes, although not to levels observed in Sham-Sed myocytes. There were no significant differences in steady-state I(to) inactivation and activation parameters among Sham-Sed, MI-Sed, and MI-HIST myocytes. Likewise, recovery from time-dependent inactivation was also similar among the three groups. We suggest that normalization of APD after MI by HIST may be mediated by restoration of I(to) toward normal levels.
Fluid-kinetic simulations of the passage of Storm Enhanced Density (SED) plasma flux tubes through the dayside cleft auroral processes region

NASA Astrophysics Data System (ADS)

Zeng, W.; Horwitz, J. L.

2007-12-01

Foster et al. [2002] and others have reported on elevated ionospheric density regions being convected from the subauroral plasmaspheric region toward noon, in association with convection of plasmaspheric tails in the dayside magnetosphere. It has been suggested that these so-called Storm Enhanced Density (SED) regions could serve as ionospheric plasma source populations for cleft ion fountain outflows. To investigate this scenario, we have used our Dynamic Fluid Kinetic (DyFK) model to simulate the entry of a high-density "plasmasphere-like" flux tube entering the cleft region and subjected to an episode of wave-driven transverse ion heating. We find that the O+ ion density at higher altitudes increases and the density at lower altitudes decreases, following this heating episode, indicating increased numbers of O+ ions from the ionospheric source gain sufficient energy to reach higher altitudes after the effects of transverse wave heating. We also find that O+- H+ crossing point in topside ionosphere moves upward as the wave heating continues. Foster, J. C., P. J. Erickson, A. J. Coster, J. Goldstein, and F. J. Rich, Ionospheric signatures of plasmaspheric tails, Geophys. Res. Lett., 29(13), 1623, doi:10.1029/2002GL015067, 2002.
Ionospheric response to 17 March 2013 geomagnetic storm identified by data assimilation result

NASA Astrophysics Data System (ADS)

Yue, Xinan; Zhao, Biqiang; Hu, Lianhuan; She, Chengli

2017-04-01

Based on slant total electron content (TEC) observations made by 10 satellites and 450 ground IGS GNSS stations, we constructed a 4-D ionospheric electron density reanalysis during the March 17, 2013 geomagnetic storm. Four main large-scale ionospheric disturbances are identified from reanalysis: (1) The positive storm during the initial phase; (2) The SED (storm enhanced density) structure in both northern and southern hemisphere; (3) The large positive storm in main phase; (4) The significant negative storm in middle and low latitude during recovery phase. We then run the NCAR-TIEGCM model with Heelis electric potential empirical model as polar input. The TIEGCM can reproduce 3 of 4 large-scale structures (except SED) very well. We then further analyzed the altitudinal variations of these large-scale disturbances and found several interesting things, such as the altitude variation of SED, the rotation of positive/negative storm phase with local time. Those structures could not be identified clearly by traditional used data sources, which either has no global coverage or no vertical resolution. The drivers such as neutral wind/density and electric field from TIEGCM simulations are also analyzed to self-consistently explain the identified disturbance features.
Large Scale Ionospheric Response During March 17, 2013 Geomagnetic Storm: Reanalysis Based on Multiple Satellites Observations and TIEGCM Simulations

NASA Astrophysics Data System (ADS)

Yue, X.; Wang, W.; Schreiner, W. S.; Kuo, Y. H.; Lei, J.; Liu, J.; Burns, A. G.; Zhang, Y.; Zhang, S.

2015-12-01

Based on slant total electron content (TEC) observations made by ~10 satellites and ~450 ground IGS GNSS stations, we constructed a 4-D ionospheric electron density reanalysis during the March 17, 2013 geomagnetic storm. Four main large-scale ionospheric disturbances are identified from reanalysis: (1) The positive storm during the initial phase; (2) The SED (storm enhanced density) structure in both northern and southern hemisphere; (3) The large positive storm in main phase; (4) The significant negative storm in middle and low latitude during recovery phase. We then run the NCAR-TIEGCM model with Heelis electric potential empirical model as polar input. The TIEGCM can reproduce 3 of 4 large-scale structures (except SED) very well. We then further analyzed the altitudinal variations of these large-scale disturbances and found several interesting things, such as the altitude variation of SED, the rotation of positive/negative storm phase with local time. Those structures could not be identified clearly by traditional used data sources, which either has no gloval coverage or no vertical resolution. The drivers such as neutral wind/density and electric field from TIEGCM simulations are also analyzed to self-consistantly explain the identified disturbance features.
Hibiscus chlorotic ringspot virus coat protein upregulates sulfur metabolism genes for enhanced pathogen defense.

PubMed

Gao, Ruimin; Ng, Florence Kai Lin; Liu, Peng; Wong, Sek-Man

2012-12-01

In both Hibiscus chlorotic ringspot virus (HCRSV)-infected and HCRSV coat protein (CP) agroinfiltrated plant leaves, we showed that sulfur metabolism pathway related genes-namely, sulfite oxidase (SO), sulfite reductase, and adenosine 5'-phosphosulfate kinase-were upregulated. It led us to examine a plausible relationship between sulfur-enhanced resistance (SED) and HCRSV infection. We broadened an established method to include different concentrations of sulfur (0S, 1S, 2S, and 3S) to correlate them to symptom development of HCRSV-infected plants. We treated plants with glutathione and its inhibitor to verify the SED effect. Disease resistance was induced through elevated glutathione contents during HCRSV infection. The upregulation of SO was related to suppression of symptom development induced by sulfur treatment. In this study, we established that HCRSV-CP interacts with SO which, in turn, triggers SED and leads to enhanced plant resistance. Thus, we have discovered a new function of SO in the SED pathway. This is the first report to demonstrate that the interaction of a viral protein and host protein trigger SED in plants. It will be interesting if such interaction applies generally to other host-pathogen interactions that will lead to enhanced pathogen defense.
Study of Saturn Electrostatic Discharges in a Wide Range of Timec SCALES

NASA Astrophysics Data System (ADS)

Mylostna, K.; Zakharenko, V.; Konovalenko, A.; Kolyadin, V.; Zarka, P.; Griemeier, J.-M.; Litvinenko, G.; Sidorchuk, M.; Rucker, H.; Fischer, G.; Cecconi, B.; Coffre, A.; Denis, L.; Nikolaenko, V.; Shevchenko, V.

Saturn Electrostatic discharges (SED) are sporadic broadband impulsive radio bursts associated with lightning in Saturnian atmosphere. After 25 years of space investigations in 2006 the first successful observations of SED on the UTR-2 radio telescope were carried out [1]. Since 2007 a long-term program of ED search and study in the Solar system has started. As a part of this program the unique observations with high time resolution were taken in 2010. New possibilities of UTR-2 radio telescope allowed to provide a long-period observations and study with high temporal resolution. This article presents the results of SED study in a wide range of time scales: from seconds to microseconds. For the first time there were obtained a low frequency spectrum of SED. We calculated flux densities of individual bursts at the maximum achievable time resolution. Flux densities of most intensive bursts reach 4200 Jy.
Physical Modeling of the Processes Responsible for the Mid-Latitude Storm Enhanced Plasma Density

NASA Astrophysics Data System (ADS)

Fuller-Rowell, T. J.; Maruyama, N.; Fedrizzi, M.; Codrescu, M.; Heelis, R. A.

2016-12-01

Certain magnetic local time sectors at mid latitudes see substantial increases in plasma density in the early phases of a geomagnetic storm. The St. Patrick's Day storms of 2013 and 2015 were no exception, both producing large increases of total electron content at mid latitudes. There are theories for the build up of the storm enhanced density (SED), but can current theoretical ionosphere-thermosphere coupled models actually reproduce the response for an actual event? Not only is it necessary for the physical model to contain the appropriate physics, they also have to be forced by the correct drivers. The SED requires mid-latitude zonal transport to provide plasma stagnation in sunlight to provide the production. The theory also requires a poleward drift perpendicular to the magnetic field to elevate the plasma out of the body of the thermosphere to regions of substantially less loss rate. It is also suggested that equatorward winds are necessary to further elevate the plasma to regions of reduced loss. However, those same winds are also likely to transport molecular nitrogen rich neutral gas equatorward, potentially canceling out the benefits of the neutral circulation. Observations of mid-latitude zonal plasma flow are first analyzed to see if this first necessary ingredient is substantiated. The drift observations are then used to tune the driver to determine if, with the appropriate electric field driver, the latest physical models can reproduce the substantial plasma build up. If it can, the simulation can also be used to assess the contribution of the equatorward meridional wind; are they an asset to the plasma build up, or does the enhanced molecular species they carry counteract their benefit.
Crystallization of pure anhydrous polymorphs of carbamazepine by solution enhanced dispersion with supercritical fluids (SEDS).

PubMed

Edwards, A D; Shekunov, B Y; Kordikowski, A; Forbes, R T; York, P

2001-08-01

Pure anhydrous polymorphs of carbamazepine were prepared by solution-enhanced dispersion with supercritical fluids (SEDS). Crystallization of the polymorphs was studied. Mechanisms are proposed that consider the thermodynamics of carbamazepine, supersaturation in the SEDS process, and the binary phase equilibria of organic solvents and the carbon dioxide antisolvent. alpha-Carbamazepine was crystallized at high supersaturations and low temperatures, beta-carbamazepine crystallized from a methanol-carbon dioxide phase split, and gamma-carbamazepine crystallized via nucleation at high temperatures and low supersaturation. Copyright 2001 Wiley-Liss, Inc.
Enhanced oral bioavailability of silymarin using liposomes containing a bile salt: preparation by supercritical fluid technology and evaluation in vitro and in vivo

PubMed Central

Yang, Gang; Zhao, Yaping; Zhang, Yongtai; Dang, Beilei; Liu, Ying; Feng, Nianping

2015-01-01

The aim of this investigation was to develop a procedure to improve the dissolution and bioavailability of silymarin (SM) by using bile salt-containing liposomes that were prepared by supercritical fluid technology (ie, solution-enhanced dispersion by supercritical fluids [SEDS]). The process for the preparation of SM-loaded liposomes containing a bile salt (SM-Lip-SEDS) was optimized using a central composite design of response surface methodology with the ratio of SM to phospholipids (w/w), flow rate of solution (mL/min), and pressure (MPa) as independent variables. Particle size, entrapment efficiency (EE), and drug loading (DL) were dependent variables for optimization of the process and formulation variables. The particle size, zeta potential, EE, and DL of the optimized SM-Lip-SEDS were 160.5 nm, −62.3 mV, 91.4%, and 4.73%, respectively. Two other methods to produce SM liposomes were compared to the SEDS method. The liposomes obtained by the SEDS method exhibited the highest EE and DL, smallest particle size, and best stability compared to liposomes produced by the thin-film dispersion and reversed-phase evaporation methods. Compared to the SM powder, SM-Lip-SEDS showed increased in vitro drug release. The in vivo AUC0−t of SM-Lip-SEDS was 4.8-fold higher than that of the SM powder. These results illustrate that liposomes containing a bile salt can be used to enhance the oral bioavailability of SM and that supercritical fluid technology is suitable for the preparation of liposomes. PMID:26543366

Contribution of transposable elements and distal enhancers to evolution of human-specific features of interphase chromatin architecture in embryonic stem cells.

PubMed

Glinsky, Gennadi V

2018-03-01

Transposable elements have made major evolutionary impacts on creation of primate-specific and human-specific genomic regulatory loci and species-specific genomic regulatory networks (GRNs). Molecular and genetic definitions of human-specific changes to GRNs contributing to development of unique to human phenotypes remain a highly significant challenge. Genome-wide proximity placement analysis of diverse families of human-specific genomic regulatory loci (HSGRL) identified topologically associating domains (TADs) that are significantly enriched for HSGRL and designated rapidly evolving in human TADs. Here, the analysis of HSGRL, hESC-enriched enhancers, super-enhancers (SEs), and specific sub-TAD structures termed super-enhancer domains (SEDs) has been performed. In the hESC genome, 331 of 504 (66%) of SED-harboring TADs contain HSGRL and 68% of SEDs co-localize with HSGRL, suggesting that emergence of HSGRL may have rewired SED-associated GRNs within specific TADs by inserting novel and/or erasing existing non-coding regulatory sequences. Consequently, markedly distinct features of the principal regulatory structures of interphase chromatin evolved in the hESC genome compared to mouse: the SED quantity is 3-fold higher and the median SED size is significantly larger. Concomitantly, the overall TAD quantity is increased by 42% while the median TAD size is significantly decreased (p = 9.11E-37) in the hESC genome. Present analyses illustrate a putative global role for transposable elements and HSGRL in shaping the human-specific features of the interphase chromatin organization and functions, which are facilitated by accelerated creation of novel transcription factor binding sites and new enhancers driven by targeted placement of HSGRL at defined genomic coordinates. A trend toward the convergence of TAD and SED architectures of interphase chromatin in the hESC genome may reflect changes of 3D-folding patterns of linear chromatin fibers designed to enhance both regulatory complexity and functional precision of GRNs by creating predominantly a single gene (or a set of functionally linked genes) per regulatory domain structures. Collectively, present analyses reveal critical evolutionary contributions of transposable elements and distal enhancers to creation of thousands primate- and human-specific elements of a chromatin folding code, which defines the 3D context of interphase chromatin both restricting and facilitating biological functions of GRNs.
Analysis of ProSEDS Test of Bare-Tether Collection

NASA Technical Reports Server (NTRS)

Sanmartin, J. R.; Lorenzini, E. C.; Estes, R. D.; Charro, M.; Cosmo, M. L.

2003-01-01

NASA's tether experiment ProSEDS will be placed in orbit on board a Delta-II rocket to test bare-tether electron collection, deorbiting of the rocket second stage, and the system dynamic stability. ProSEDS performance will vary because ambient conditions change along the orbit and tether-circuit bulk elements at the cathodic end follow the step-by-step sequence for the current cycles of operating modes (open-circuit, shunt and resistor modes for primary cycles; shunt and battery modes for secondary cycles). In this work we discuss expected ProSEDS values of the ratio L,/L*, which jointly with cathodic bulk elements determines bias and current tether profiles; L, is tether length, and L* (changing with tether temperature and ionospheric plasma density and magnetic field) is a characteristic length gauging ohmic versus baretether collection impedances. We discuss how to test bare-tether electron collection during primary cycles, using probe measurements of plasma density, measurements of cathodic current in resistor and shunt modes, and an estimate of tether temperature based on ProSEDS orbital position at the particular cycle concerned. We discuss how a temperature misestimate might occasionally affect the test of bare-tether collection, and how introducing the battery mode in some primary cycles, for an additional current measurement, could obviate the need of a temperature estimate. We also show how to test bare-tether collection by estimating orbit-decay rate from measurements of cathodic current for the shunt and battery modes of secondary cycles.
Towards Sustainable H2 Production: Rational Design of Hydrophobic Triphenylamine-based Dyes for Sensitized Ethanol Photoreforming.

PubMed

Dessì, Alessio; Monai, Matteo; Bessi, Matteo; Montini, Tiziano; Calamante, Massimo; Mordini, Alessandro; Reginato, Gianna; Trono, Cosimo; Fornasiero, Paolo; Zani, Lorenzo

2018-02-22

Donor-acceptor dyes are a well-established class of photosensitizers, used to enhance visible-light harvesting in solar cells and in direct photocatalytic reactions, such as H 2 production by photoreforming of sacrificial electron donors (SEDs). Amines-typically triethanolamine (TEOA)-are commonly employed as SEDs in such reactions. Dye-sensitized photoreforming of more sustainable, biomass-derived alcohols, on the other hand, was only recently reported by using methanol as the electron donor. In this work, several rationally designed donor-acceptor dyes were used as sensitizers in H 2 photocatalytic production, comparing the efficiency of TEOA and EtOH as SEDs. In particular, the effect of hydrophobic chains in the spacer and/or the donor unit of the dyes was systematically studied. The H 2 production rates were higher when TEOA was used as SED, whereas the activity trends depended on the SED used. The best performance was obtained with TEOA by using a sensitizer with just one bulky hydrophobic moiety, propylenedioxythiophene, placed on the spacer unit. In the case of EtOH, the best-performing sensitizers were the ones featuring a thiazolo[5,4-d]thiazole internal unit, needed for enhancing light harvesting, and carrying alkyl chains on both the donor part and the spacer unit. The results are discussed in terms of reaction mechanism, interaction with the SED, and structural/electrochemical properties of the sensitizers. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
45 CFR 1336.33 - Eligible applicants and proposed activities which are ineligible.

Code of Federal Regulations, 2014 CFR

2014-10-01

... served. (1) Social and Economic Development Strategies (SEDS) and Preservation and Enhancement of Native... 42 U.S.C. 2991b-3) (2) Alaska-Specific Social and Economic Development Strategies (SEDS) Projects: (i... carry out project objectives, is acceptable; (2) Projects that request funds for feasibility studies...
45 CFR 1336.33 - Eligible applicants and proposed activities which are ineligible.

Code of Federal Regulations, 2011 CFR

2011-10-01

... served. (1) Social and Economic Development Strategies (SEDS) and Preservation and Enhancement of Native... 42 U.S.C. 2991b-3) (2) Alaska-Specific Social and Economic Development Strategies (SEDS) Projects: (i... carry out project objectives, is acceptable; (2) Projects that request funds for feasibility studies...
De-blending deep Herschel surveys: A multi-wavelength approach

NASA Astrophysics Data System (ADS)

Pearson, W. J.; Wang, L.; van der Tak, F. F. S.; Hurley, P. D.; Burgarella, D.; Oliver, S. J.

2017-07-01

Aims: Cosmological surveys in the far-infrared are known to suffer from confusion. The Bayesian de-blending tool, XID+, currently provides one of the best ways to de-confuse deep Herschel SPIRE images, using a flat flux density prior. This work is to demonstrate that existing multi-wavelength data sets can be exploited to improve XID+ by providing an informed prior, resulting in more accurate and precise extracted flux densities. Methods: Photometric data for galaxies in the COSMOS field were used to constrain spectral energy distributions (SEDs) using the fitting tool CIGALE. These SEDs were used to create Gaussian prior estimates in the SPIRE bands for XID+. The multi-wavelength photometry and the extracted SPIRE flux densities were run through CIGALE again to allow us to compare the performance of the two priors. Inferred ALMA flux densities (FinferALMA), at 870 μm and 1250 μm, from the best fitting SEDs from the second CIGALE run were compared with measured ALMA flux densities (FmeasALMA) as an independent performance validation. Similar validations were conducted with the SED modelling and fitting tool MAGPHYS and modified black-body functions to test for model dependency. Results: We demonstrate a clear improvement in agreement between the flux densities extracted with XID+ and existing data at other wavelengths when using the new informed Gaussian prior over the original uninformed prior. The residuals between FmeasALMA and FinferALMA were calculated. For the Gaussian priors these residuals, expressed as a multiple of the ALMA error (σ), have a smaller standard deviation, 7.95σ for the Gaussian prior compared to 12.21σ for the flat prior; reduced mean, 1.83σ compared to 3.44σ; and have reduced skew to positive values, 7.97 compared to 11.50. These results were determined to not be significantly model dependent. This results in statistically more reliable SPIRE flux densities and hence statistically more reliable infrared luminosity estimates. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.
45 CFR 1336.33 - Eligible applicants and proposed activities which are ineligible.

Code of Federal Regulations, 2010 CFR

2010-10-01

... served. (1) Social and Economic Development Strategies (SEDS) and Preservation and Enhancement of Native... 42 U.S.C. 2991b-3) (2) Alaska-Specific Social and Economic Development Strategies (SEDS) Projects: (i..., business plans, marketing plans or written materials, such as manuals, that are not an essential part of...
Enhanced cell-surface display of a heterologous protein using SED1 anchoring system in SED1-disrupted Saccharomyces cerevisiae strain.

PubMed

Bamba, Takahiro; Inokuma, Kentaro; Hasunuma, Tomohisa; Kondo, Akihiko

2018-03-01

Yeast displaying enzymes on the cell surface are used for developing whole-cell biocatalysts. High enzyme activity on the cell surface is required in certain applications such as direct ethanol production from lignocellulosic materials. However, the cell surface enzyme activity is limited by several factors, one of which is the protein amount of the yeast cell wall. In this study, we attempted to improve the incorporation capacity of a displayed heterologous enzyme by disrupting a native cell-wall protein. β-Glucosidase (BGL1) from Aspergillus aculeatus was fused with Saccharomyces cerevisiae Sed1 and displayed on the cell surface of S. cerevisiae BY4741 strain and its SED1 disruptant. Sed1 is one of the most abundant stationary phase yeast cell wall protein. A time course analysis revealed that BGL1 activity of the control strain reached saturation after 48 h of cultivation. In contrast, the BGL1 activity of the SED1 disruptant increased until 72 h of cultivation and was 22% higher than that of the control strain. We also performed relative quantification of cell wall proteins of these strains by nanoscale ultra pressure liquid chromatography electrospray ionization quadrupole time-of-flight tandem mass spectrometry (nano-UPLC-MS E ). The amount of the cell wall-associated BGL1 per unit dry cell-weight of the SED1 disruptant was 19% higher than that of the control strain. These results suggested that the incorporation capacity of the cell wall for BGL1 was increased by disruption of SED1. Disruption of SED1 would be a promising approach for improving display efficiency of heterologous protein fused with Sed1. Copyright © 2017 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.
Influence of screw length and diameter on tibial strain energy density distribution after anterior cruciate ligament reconstruction

NASA Astrophysics Data System (ADS)

Yao, Jie; Kuang, Guan-Ming; Wong, Duo Wai-Chi; Niu, Wen-Xin; Zhang, Ming; Fan, Yu-Bo

2014-04-01

Postoperative tunnel enlargement has been frequently reported after anterior cruciate ligament (ACL) reconstruction. Interference screw, as a surgical implant in ACL reconstruction, may influence natural loading transmission and contribute to tunnel enlargement. The aims of this study are (1) to quantify the alteration of strain energy den sity (SED) distribution after the anatomic single-bundle ACL reconstruction; and (2) to characterize the influence of screw length and diameter on the degree of the SED alteration. A validated finite element model of human knee joint was used. The screw length ranging from 20 to 30mm with screw diameter ranging from 7 to 9 mm were investigated. In the post-operative knee, the SED increased steeply at the extra-articular tunnel aperture under compressive and complex loadings, whereas the SED decreased beneath the screw shaft and nearby the intra-articular tunnel aperture. Increasing the screw length could lower the SED deprivation in the proximal part of the bone tunnel; whereas increasing either screw length or diameter could aggravate the SED deprivation in the distal part of the bone tunnel. Decreasing the elastic modulus of the screw could lower the bone SED deprivation around the screw. In consideration of both graft stability and SED alteration, a biodegradable interference screw with a long length is recommended, which could provide a beneficial mechanical environment at the distal part of the tunnel, and meanwhile decrease the bone-graft motion and synovial fluid propagation at the proximal part of the tunnel. These findings together with the clinical and histological factors could help to improve surgical outcome, and serve as a preliminary knowledge for the following study of biodegradable interference screw. [Figure not available: see fulltext.
Exercise training-induced bradycardia: evidence for enhanced parasympathetic regulation without changes in intrinsic sinoatrial node function.

PubMed

Billman, George E; Cagnoli, Kristen L; Csepe, Thomas; Li, Ning; Wright, Patrick; Mohler, Peter J; Fedorov, Vadim V

2015-06-01

The mechanisms responsible for exercise-induced reductions in baseline heart rate (HR), known as training bradycardia, remain controversial. Therefore, changes in cardiac autonomic regulation and intrinsic sinoatrial nodal (SAN) rate were evaluated using dogs randomly assigned to either a 10- to 12-wk exercise training (Ex, n = 15) or an equivalent sedentary period (Sed, n = 10). Intrinsic HR was revealed by combined autonomic nervous system (ANS) blockade (propranolol + atropine, iv) before and after completion of the study. At the end of the study, SAN function was further evaluated by examining the SAN recovery time (SNRT) following rapid atrial pacing and the response to adenosine in anesthetized animals. As expected, both the response to submaximal exercise and baseline HR significantly (P < 0.01) decreased, and heart rate variability (HRV; e.g., high-frequency R-R interval variability) significantly (P < 0.01) increased in the Ex group but did not change in the Sed group. Atropine also induced significantly (P < 0.01) greater reductions in HRV in the Ex group compared with the Sed group; propranolol elicited similar HR and HRV changes in both groups. In contrast, neither intrinsic HR (Ex before, 141.2 ± 6.7; Ex after, 146.0 ± 8.0 vs. Sed before, 143.3 ± 11.1; Sed after, 141.0 ± 11.3 beats per minute), the response to adenosine, corrected SNRT, nor atrial fibrosis and atrial fibrillation inducibility differed in the Ex group vs. the Sed group. These data suggest that in a large-animal model, training bradycardia results from an enhanced cardiac parasympathetic regulation and not from changes in intrinsic properties of the SAN. Copyright © 2015 the American Physiological Society.
Preparation of Poly-(Methyl vinyl ether-co-maleic Anhydride) Nanoparticles by Solution-Enhanced Dispersion by Supercritical CO2

PubMed Central

Chen, Ai-Zheng; Wang, Guang-Ya; Wang, Shi-Bin; Feng, Jian-Gang; Liu, Yuan-Gang; Kang, Yong-Qiang

2012-01-01

The supercritical CO2-based technologies have been widely used in the formation of drug and/or polymer particles for biomedical applications. In this study, nanoparticles of poly-(methyl vinyl ether-co-maleic anhydride) (PVM/MA) were successfully fabricated by a process of solution-enhanced dispersion by supercritical CO2 (SEDS). A 23 factorial experiment was designed to investigate and identify the significance of the processing parameters (concentration, flow and solvent/nonsolvent) for the surface morphology, particle size, and particle size distribution of the products. The effect of the concentration of PVM/MA was found to be dominant in the results regarding particle size. Decreasing the initial solution concentration of PVM/MA decreased the particle size significantly. After optimization, the resulting PVM/MA nanoparticles exhibited a good spherical shape, a smooth surface, and a narrow particle size distribution. Fourier transform infrared spectroscopy (FTIR) spectra demonstrated that the chemical composition of PVM/MA was not altered during the SEDS process and that the SEDS process was therefore a typical physical process. The absolute value of zeta potential of the obtained PVM/MA nanoparticles was larger than 40 mV, indicating the samples’ stability in aqueous suspension. Analysis of thermogravimetry-differential scanning calorimetry (TG-DSC) revealed that the effect of the SEDS process on the thermostability of PVM/MA was negligible. The results of gas chromatography (GC) analysis confirmed that the SEDS process could efficiently remove the organic residue.
Regular exercise enhances blood pressure lowering effect of acetylcholine by increased contribution of nitric oxide.

PubMed

Dörnyei, G; Monos, E; Kaley, G; Koller, A

2000-01-01

This study is aimed to test the hypothesis, that short-term daily bouts of exercise alter the endothelial regulation of peripheral vascular resistance by nitric oxide. Rats ran on a treadmill once a day, 5 days a week, for an average of three weeks with gradually increasing intensity (EX), while a control group remained sedentary (SED). Dose dependent reductions in mean arterial blood pressure (resting MABP; SED: 120.0 +/- 3.4 and EX: 127.8 +/- 4.0 mm Hg) of pentobarbital anesthetized rats to intravenous endothelium independent dilator sodium nitropmsside (SNP; 0.6-3.0 microg/kg) were not different in EX and SED animals. In contrast, dose dependent reductions in MABP to endothelium dependent dilator acetylcholine (ACh) were significantly enhanced in EX compared to those in SED rats (at 0.5 and 1.0 microg/kg ACh: 60.3 +/- 2.4 and 66.5 +/- 1.8 vs 52.8 +/- 2.0 and 59.8 +/- 1.7 mmHg, respectively, p<0.01). There was no significant difference in the heart rate (HR) response to ACh and SNP in the two groups of rats. Intravenous administration of 20 mg/kg Nomega-nitro-L-arginine (L-NNA, a nitric oxide synthase inhibitor) elicited a similar increase (approximately 30%) in the MABP in the two groups and eliminated the difference between ACh-induced blood pressure lowering responses in EX and SED rats (at 0.5 and 1.0 microg/kg ACh: 44.6 +/- 4.7 and 56.3 +/- 4.4 vs 50.9 +/- 4.5 and 59.4 +/- 3.6 mm Hg, respectively). Thus, we suggest that the enhanced acetylcholine-induced decrease in systemic blood pressure following regular daily exercise is primarily due to the augmented synthesis of nitric oxide in the endothelium of peripheral vasculature. This change in the function of endothelium could be important in the adaptation of circulation to exercise training.
Cross Comparison of Electron Density and Electron Temperature Observations from the DICE CubeSat Langmuir Probes and the Millstone Hill Incoherent Scatter Radar.

NASA Astrophysics Data System (ADS)

Swenson, C.; Erickson, P. J.; Crowley, G.; Pilinski, M.; Barjatya, A.; Fish, C. S.

2014-12-01

The Dynamic Ionosphere CubeSat Experiment (DICE) consists of two identical 1.5U CubeSats deployed simultaneously from a single P-POD (Poly Picosatellite Orbital Deployer) into the same orbit. Several observational campaigns were planned between the DICE CubeSats and the mid-latitude Millstone Hill Incoherent Scatter Radar (ISR) in order to calibrate the DICE measurements of electron density and electron temperature. In this presentation, we compare in-situ observations from the Dynamic Ionosphere CubeSat Experiment (DICE) and from the Millstone Hill ISR. Both measurements are cross-calibrated against an assimilative model of the global ionospheric electron density. The electron density and electron temperature were obtained for three Millstone Hill DICE overflights (2013-03-12, 2013-03-15, 2013-03-17). We compare the data during quiet and geomagnetically disturbed conditions and find evidence of an storm enhanced density (SED) plume in the topside ionosphere on 2013-03-17 at 19? UTC. During this disturbed interval, American longitude sector high density plasma was convected near 15 SLT towards the noontime cusp. DICE was selected for flight under the NSF "CubeSat-based Science Mission for Space Weather and Atmospheric Research" program. The DICE twin satellites were launched on a Delta II rocket on October 28, 2011. The satellites are flying in a "leader-follower" formation in an elliptical orbit which ranges from 820 to 400 km in altitude. Each satellite carries a fixed-bias DC Langmuir Probe (DCP) to measure in-situ ionospheric plasma densities and a science grade magnetometer to measure DC and AC geomagnetic fields. The purpose of these measurements was to permit accurate identification of storm-time features such as the SED bulge and plume. The mission team combines expertise from ASTRA, Utah State University/Space Dynamics Laboratory (USU/SDL), and Embry-Riddle Aeronautical University. In this paper we present a comparison of data from DICE and Millstone Hill ISR during quiet and magnetically disturbed conditions.
Spatially resolved star formation and dust attenuation in Mrk 848: Comparison of the integral field spectra and the UV-to-IR SED

NASA Astrophysics Data System (ADS)

Yuan, Fang-Ting; Argudo-Fernández, María; Shen, Shiyin; Hao, Lei; Jiang, Chunyan; Yin, Jun; Boquien, Médéric; Lin, Lihwai

2018-05-01

We investigate the star formation history and the dust attenuation in the galaxy merger Mrk 848. Thanks to the multiwavelength photometry from the ultraviolet (UV) to the infrared (IR), and MaNGA's integral field spectroscopy, we are able to study this merger in a detailed way. We divide the whole merger into the core and tail regions, and fit both the optical spectrum and the multi-band spectral energy distribution (SED) to models to obtain the star formation properties for each region respectively. We find that the color excess of stars in the galaxy E(B-V)sSED measured with the multi-band SED fitting is consistent with that estimated both from the infrared excess (the ratio of IR to UV flux) and from the slope of the UV continuum. Furthermore, the reliability of the E(B-V)sSED is examined with a set of mock SEDs, showing that the dust attenuation of the stars can be well constrained by the UV-to-IR broadband SED fitting. The dust attenuation obtained from optical continuum E(B-V)sspec is only about half of E(B-V)sSED. The ratio of the E(B-V)sspec to the E(B-V)g obtained from the Balmer decrement is consistent with the local value (around 0.5). The difference between the results from the UV-to-IR data and the optical data is consistent with the picture that younger stellar populations are attenuated by an extra dust component from the birth clouds compared to older stellar populations which are only attenuated by the diffuse dust. Both with the UV-to-IR SED fitting and the spectral fitting, we find that there is a starburst younger than 100 Myr in one of the two core regions, consistent with the scenario that the interaction-induced gas inflow can enhance the star formation in the center of galaxies.
The radio spectral energy distribution of infrared-faint radio sources

NASA Astrophysics Data System (ADS)

Herzog, A.; Norris, R. P.; Middelberg, E.; Seymour, N.; Spitler, L. R.; Emonts, B. H. C.; Franzen, T. M. O.; Hunstead, R.; Intema, H. T.; Marvil, J.; Parker, Q. A.; Sirothia, S. K.; Hurley-Walker, N.; Bell, M.; Bernardi, G.; Bowman, J. D.; Briggs, F.; Cappallo, R. J.; Callingham, J. R.; Deshpande, A. A.; Dwarakanath, K. S.; For, B.-Q.; Greenhill, L. J.; Hancock, P.; Hazelton, B. J.; Hindson, L.; Johnston-Hollitt, M.; Kapińska, A. D.; Kaplan, D. L.; Lenc, E.; Lonsdale, C. J.; McKinley, B.; McWhirter, S. R.; Mitchell, D. A.; Morales, M. F.; Morgan, E.; Morgan, J.; Oberoi, D.; Offringa, A.; Ord, S. M.; Prabu, T.; Procopio, P.; Udaya Shankar, N.; Srivani, K. S.; Staveley-Smith, L.; Subrahmanyan, R.; Tingay, S. J.; Wayth, R. B.; Webster, R. L.; Williams, A.; Williams, C. L.; Wu, C.; Zheng, Q.; Bannister, K. W.; Chippendale, A. P.; Harvey-Smith, L.; Heywood, I.; Indermuehle, B.; Popping, A.; Sault, R. J.; Whiting, M. T.

2016-10-01

Context. Infrared-faint radio sources (IFRS) are a class of radio-loud (RL) active galactic nuclei (AGN) at high redshifts (z ≥ 1.7) that are characterised by their relative infrared faintness, resulting in enormous radio-to-infrared flux density ratios of up to several thousand. Aims: Because of their optical and infrared faintness, it is very challenging to study IFRS at these wavelengths. However, IFRS are relatively bright in the radio regime with 1.4 GHz flux densities of a few to a few tens of mJy. Therefore, the radio regime is the most promising wavelength regime in which to constrain their nature. We aim to test the hypothesis that IFRS are young AGN, particularly GHz peaked-spectrum (GPS) and compact steep-spectrum (CSS) sources that have a low frequency turnover. Methods: We use the rich radio data set available for the Australia Telescope Large Area Survey fields, covering the frequency range between 150 MHz and 34 GHz with up to 19 wavebands from different telescopes, and build radio spectral energy distributions (SEDs) for 34 IFRS. We then study the radio properties of this class of object with respect to turnover, spectral index, and behaviour towards higher frequencies. We also present the highest-frequency radio observations of an IFRS, observed with the Plateau de Bure Interferometer at 105 GHz, and model the multi-wavelength and radio-far-infrared SED of this source. Results: We find IFRS usually follow single power laws down to observed frequencies of around 150 MHz. Mostly, the radio SEDs are steep (α < -0.8; %), but we also find ultra-steep SEDs (α < -1.3; %). In particular, IFRS show statistically significantly steeper radio SEDs than the broader RL AGN population. Our analysis reveals that the fractions of GPS and CSS sources in the population of IFRS are consistent with the fractions in the broader RL AGN population. We find that at least % of IFRS contain young AGN, although the fraction might be significantly higher as suggested by the steep SEDs and the compact morphology of IFRS. The detailed multi-wavelength SED modelling of one IFRS shows that it is different from ordinary AGN, although it is consistent with a composite starburst-AGN model with a star formation rate of 170 M⊙ yr-1. Based on observations carried out with the IRAM Plateau de Bure Interferometer. IRAM is supported by INSU/CNRS (France), MPG (Germany) and IGN (Spain).
Modeling the near-ultraviolet band of GK stars. III. Dependence on abundance pattern

DOE Office of Scientific and Technical Information (OSTI.GOV)

Short, C. Ian; Campbell, Eamonn A., E-mail: ishort@ap.smu.ca

2013-06-01

We extend the grid of non-LTE (NLTE) models presented in Paper II to explore variations in abundance pattern in two ways: (1) the adoption of the Asplund et al. (GASS10) abundances, (2) for stars of metallicity, [M/H], of –0.5, the adoption of a non-solar enhancement of α-elements by +0.3 dex. Moreover, our grid of synthetic spectral energy distributions (SEDs) is interpolated to a finer numerical resolution in both T {sub eff} (ΔT {sub eff} = 25 K) and log g (Δlog g = 0.25). We compare the values of T {sub eff} and log g inferred from fitting LTE andmore » NLTE SEDs to observed SEDs throughout the entire visible band, and in an ad hoc 'blue' band. We compare our spectrophotometrically derived T {sub eff} values to a variety of T {sub eff} calibrations, including more empirical ones, drawn from the literature. For stars of solar metallicity, we find that the adoption of the GASS10 abundances lowers the inferred T {sub eff} value by 25-50 K for late-type giants, and NLTE models computed with the GASS10 abundances give T {sub eff} results that are marginally in better agreement with other T {sub eff} calibrations. For stars of [M/H] = –0.5 there is marginal evidence that adoption of α-enhancement further lowers the derived T {sub eff} value by 50 K. Stellar parameters inferred from fitting NLTE models to SEDs are more dependent than LTE models on the wavelength region being fitted, and we find that the effect depends on how heavily line blanketed the fitting region is, whether the fitting region is to the blue of the Wien peak of the star's SED, or both.« less
Modeling Protoplanetary Disks to Characterize the Evolution of their Structure

NASA Astrophysics Data System (ADS)

Allen, Magdelena; van der Marel, Nienke; Williams, Jonathan

2018-01-01

Stars form from gravitationally collapsing clouds of gas and dust. Most young stars retain a protoplanetary disk for a few million years. This disk’s dust reemits stellar flux in the infrared, producing a spectral energy distribution (SED) observable by Spitzer and other telescopes. To understand the inner clearing of dust cavities and evolution in the SED, we used the Chiang & Goldreich two-layer approximation. We first wrote a python script based on refinements by Dullemond that includes a hot, puffed inner rim, shadowed mid region, flaring outer disk, and a variable inner cavity. This was then coupled with a Markov Chain Monte Carlo procedure to fit the observed SEDs of disks in the star forming Lupus region. The fitting procedure recovers physical characteristics of the disk including temperature, size, mass, and surface density. We compare the characteristics of circumstellar disks without holes and more evolved transition disks with cleared inner regions.
Voluntary wheel running selectively augments insulin-stimulated vasodilation in arterioles from white skeletal muscle of insulin-resistant rats.

PubMed

Mikus, Catherine R; Roseguini, Bruno T; Uptergrove, Grace M; Morris, E Matthew; Rector, Randy Scott; Libla, Jessica L; Oberlin, Douglas J; Borengasser, Sarah J; Taylor, Angelina M; Ibdah, Jamal A; Laughlin, Maurice Harold; Thyfault, John P

2012-11-01

Exercise (RUN) prevents declines in insulin-mediated vasodilation, an important component of insulin-mediated glucose disposal, in rats prone to obesity and insulin resistance. Determine whether RUN (1) improves insulin-stimulated vasodilation after insulin resistance has been established, and (2) differentially affects arterioles from red and white muscle. Insulin signaling and vasoreactivity to insulin (1-1000 μIU/mL) were assessed in 2A from the Gw and Gr of SED OLETF rats at 12 and 20 weeks of age (SED12, SED20) and those undergoing RUN (RUN20) or caloric restriction (CR20; to match body weight of RUN) from 12 to 20 weeks. Glucose and insulin responses to i.p. glucose were reduced in RUN20, elevated in SED20 (p < 0.05 vs. SED12), and maintained in CR20. Insulin-stimulated vasodilation was greater in Gw but not Gr, 2As of RUN20 (p < 0.01 vs. all groups), and was improved by ET-1 receptor inhibition in Gw 2As from SED20 and CR20 (p < 0.05). There were no differences in microvascular insulin signaling among groups or muscle beds. RUN selectively improved insulin-mediated vasodilation in Gw 2As, in part through attenuated ET-1 sensitivity/production, an adaptation that was independent of changes in adiposity and may contribute to enhanced insulin-stimulated glucose disposal. © 2012 John Wiley & Sons Ltd.
Do siblings always form and evolve simultaneously? Testing the coevality of multiple protostellar systems through SEDs

NASA Astrophysics Data System (ADS)

Murillo, N. M.; van Dishoeck, E. F.; Tobin, J. J.; Fedele, D.

2016-07-01

Context. Multiplicity is common in field stars and among protostellar systems. Models suggest two paths of formation: turbulent fragmentation and protostellar disk fragmentation. Aims: We attempt to find whether or not the coevality frequency of multiple protostellar systems can help to better understand their formation mechanism. The coevality frequency is determined by constraining the relative evolutionary stages of the components in a multiple system. Methods: Spectral energy distributions (SEDs) for known multiple protostars in Perseus were constructed from literature data. Herschel PACS photometric maps were used to sample the peak of the SED for systems with separations ≥7″, a crucial aspect in determining the evolutionary stage of a protostellar system. Inclination effects and the surrounding envelope and outflows were considered to decouple source geometry from evolution. This together with the shape and derived properties from the SED was used to determine each system's coevality as accurately as possible. SED models were used to examine the frequency of non-coevality that is due to geometry. Results: We find a non-coevality frequency of 33 ± 10% from the comparison of SED shapes of resolved multiple systems. Other source parameters suggest a somewhat lower frequency of non-coevality. The frequency of apparent non-coevality that is due to random inclination angle pairings of model SEDs is 17 ± 0.5%. Observations of the outflow of resolved multiple systems do not suggest significant misalignments within multiple systems. Effects of unresolved multiples on the SED shape are also investigated. Conclusions: We find that one-third of the multiple protostellar systems sampled here are non-coeval, which is more than expected from random geometric orientations. The other two-thirds are found to be coeval. Higher order multiples show a tendency to be non-coeval. The frequency of non-coevality found here is most likely due to formation and enhanced by dynamical evolution.
Spitzer Infrared Spectrograph Observations of the Galactic Center: Quantifying the Extreme Ultraviolet/Soft X-ray Fluxes

NASA Astrophysics Data System (ADS)

Simpson, Janet P.

2018-04-01

It has long been shown that the extreme ultraviolet spectrum of the ionizing stars of H II regions can be estimated by comparing the observed line emission to detailed models. In the Galactic Center (GC), however, previous observations have shown that the ionizing spectral energy distribution (SED) of the local photon field is strange, producing both very low excitation ionized gas (indicative of ionization by late O stars) and also widespread diffuse emission from atoms too highly ionized to be found in normal H II regions. This paper describes the analysis of all GC spectra taken by Spitzer's Infrared Spectrograph and downloaded from the Spitzer Heritage Archive. In it, H II region densities and abundances are described, and serendipitously discovered candidate planetary nebulae, compact shocks, and candidate young stellar objects are tabulated. Models were computed with Cloudy, using SEDs from Starburst99 plus additional X-rays, and compared to the observed mid-infrared forbidden and recombination lines. The ages inferred from the model fits do not agree with recent proposed star formation sequences (star formation in the GC occurring along streams of gas with density enhancements caused by close encounters with the black hole, Sgr A*), with Sgr B1, Sgr C, and the Arches Cluster being all about the same age, around 4.5 Myr old, with similar X-ray requirements. The fits for the Quintuplet Cluster appear to give a younger age, but that could be caused by higher-energy photons from shocks from stellar winds or from a supernova.

SOD-1 expression in pig coronary arterioles is increased by exercise training.

PubMed

Rush, J W; Laughlin, M H; Woodman, C R; Price, E M

2000-11-01

Coronary arterioles of exercise-trained (EX) pigs have enhanced nitric oxide (NO.)-dependent dilation. Evidence suggests that the biological half-life of NO. depends in part on the management of the superoxide anion. The purpose of this study was to test the hypothesis that expression of cytosolic copper/zinc-dependent superoxide dismutase (SOD)-1 is increased in coronary arterioles as a result of exercise training. Male Yucatan pigs either remained sedentary (SED, n = 4) or were EX (n = 4) on a motorized treadmill for 16-20 wk. Individual coronary arterioles ( approximately 100-microm unpressurized internal diameter) were dissected and frozen. Coronary arteriole SOD-1 protein (via immunoblots) increased as a result of exercise training (2.16 +/- 0.35 times SED levels) as did SOD-1 enzyme activity (measured via inhibition of pyrogallol autooxidation; approximately 75% increase vs. SED). In addition, SOD-1 mRNA levels (measured via RT-PCR) were higher in EX arterioles (1.68 +/- 0.16 times the SED levels). There were no effects of exercise training on the levels of SOD-2 (mitochondrial), catalase, or p67(phox) proteins. Thus chronic aerobic exercise training selectively increases the levels of SOD-1 mRNA, protein, and enzymatic activity in porcine coronary arterioles. Increased SOD-1 could contribute to the enhanced NO.-dependent dilation previously observed in EX porcine coronary arterioles by improving management of superoxide in the vascular cell environment, thus prolonging the biological half-life of NO.
SedCT: MATLAB™ tools for standardized and quantitative processing of sediment core computed tomography (CT) data collected using a medical CT scanner

NASA Astrophysics Data System (ADS)

Reilly, B. T.; Stoner, J. S.; Wiest, J.

2017-08-01

Computed tomography (CT) of sediment cores allows for high-resolution images, three-dimensional volumes, and down core profiles. These quantitative data are generated through the attenuation of X-rays, which are sensitive to sediment density and atomic number, and are stored in pixels as relative gray scale values or Hounsfield units (HU). We present a suite of MATLAB™ tools specifically designed for routine sediment core analysis as a means to standardize and better quantify the products of CT data collected on medical CT scanners. SedCT uses a graphical interface to process Digital Imaging and Communications in Medicine (DICOM) files, stitch overlapping scanned intervals, and create down core HU profiles in a manner robust to normal coring imperfections. Utilizing a random sampling technique, SedCT reduces data size and allows for quick processing on typical laptop computers. SedCTimage uses a graphical interface to create quality tiff files of CT slices that are scaled to a user-defined HU range, preserving the quantitative nature of CT images and easily allowing for comparison between sediment cores with different HU means and variance. These tools are presented along with examples from lacustrine and marine sediment cores to highlight the robustness and quantitative nature of this method.
A comparison of sedimentary DNA and pollen from lake sediments in recording vegetation composition at the Siberian treeline.

PubMed

Niemeyer, Bastian; Epp, Laura S; Stoof-Leichsenring, Kathleen R; Pestryakova, Luidmila A; Herzschuh, Ulrike

2017-11-01

Reliable information on past and present vegetation is important to project future changes, especially for rapidly transitioning areas such as the boreal treeline. To study past vegetation, pollen analysis is common, while current vegetation is usually assessed by field surveys. Application of detailed sedimentary DNA (sedDNA) records has the potential to enhance our understanding of vegetation changes, but studies systematically investigating the power of this proxy are rare to date. This study compares sedDNA metabarcoding and pollen records from surface sediments of 31 lakes along a north-south gradient of increasing forest cover in northern Siberia (Taymyr peninsula) with data from field surveys in the surroundings of the lakes. sedDNA metabarcoding recorded 114 plant taxa, about half of them to species level, while pollen analyses identified 43 taxa, both exceeding the 31 taxa found by vegetation field surveys. Increasing Larix percentages from north to south were consistently recorded by all three methods and principal component analyses based on percentage data of vegetation surveys and DNA sequences separated tundra from forested sites. Comparisons of the ordinations using procrustes and protest analyses show a significant fit among all compared pairs of records. Despite similarities of sedDNA and pollen records, certain idiosyncrasies, such as high percentages of Alnus and Betula in all pollen and high percentages of Salix in all sedDNA spectra, are observable. Our results from the tundra to single-tree tundra transition zone show that sedDNA analyses perform better than pollen in recording site-specific richness (i.e., presence/absence of taxa in the vicinity of the lake) and perform as well as pollen in tracing vegetation composition. © 2017 John Wiley & Sons Ltd.
Microencapsulation of puerarin nanoparticles by poly(l-lactide) in a supercritical CO(2) process.

PubMed

Chen, Ai-Zheng; Li, Yi; Chau, Foo-Tim; Lau, Tsui-Yan; Hu, Jun-Yan; Zhao, Zheng; Mok, Daniel Kam-Wah

2009-10-01

Puerarin nanoparticles were firstly prepared in the process of solution-enhanced dispersion by supercritical CO(2) (SEDS) and then successfully microencapsulated by poly(l-lactide) (PLLA) in a modified SEDS process. By adding an organic non-solvent, an initial puerarin solution with a higher degree of saturation and lower concentration was obtained and applied in the SEDS process. The resulting puerarin nanoparticles were then suspended in PLLA solution and microencapsulated by PLLA in a modified SEDS process, where an 'injector' was employed in the particle suspension delivery system. The puerarin nanoparticles exhibited a good spherical shape, a smooth surface and a narrow particle size distribution with a mean particle size of 188 nm. After microencapsulation the puerarin-PLLA microparticles had a mean size of 675 nm, a drug load of 23.6% and an encapsulation efficiency of 39.4%; after a burst release at the first stage, the drug was released in a sustained process. Compared with the parallel study of a co-precipitation process, this microencapsulation process is a much more promising technique to prepare a drug-polymer carrier for a drug delivery system, especially for protein drugs.
The imprint of rapid star formation quenching on the spectral energy distributions of galaxies

NASA Astrophysics Data System (ADS)

Ciesla, L.; Boselli, A.; Elbaz, D.; Boissier, S.; Buat, V.; Charmandaris, V.; Schreiber, C.; Béthermin, M.; Baes, M.; Boquien, M.; De Looze, I.; Fernández-Ontiveros, J. A.; Pappalardo, C.; Spinoglio, L.; Viaene, S.

2016-01-01

In high density environments, the gas content of galaxies is stripped, leading to a rapid quenching of their star formation activity. This dramatic environmental effect, which is not related to typical passive evolution, is generally not taken into account in the star formation histories (SFHs) usually assumed to perform spectral energy distribution (SED) fitting of these galaxies, yielding a poor fit of their stellar emission and, consequently, biased estimate of the star formation rate (SFR). In this work, we aim at reproducing this rapid quenching using a truncated delayed SFH that we implemented in the SED fitting code CIGALE. We show that the ratio between the instantaneous SFR and the SFR just before the quenching (rSFR) is well constrained as long as rest-frame UV data are available. This SED modeling is applied to the Herschel Reference Survey (HRS) containing isolated galaxies and sources falling in the dense environment of the Virgo cluster. The latter are Hi-deficient because of ram pressure stripping. We show that the truncated delayed SFH successfully reproduces their SED, while typical SFH assumptions fail. A good correlation is found between rSFR and Hi-def, the parameter that quantifies the gas deficiency of cluster galaxies, meaning that SED fitting results can be used to provide a tentative estimate of the gas deficiency of galaxies for which Hi observations are not available. The HRS galaxies are placed on the SFR-M∗ diagram showing that the Hi-deficient sources lie in the quiescent region, thus confirming previous studies. Using the rSFR parameter, we derive the SFR of these sources before quenching and show that they were previously on the main sequence relation. We show that the rSFR parameter is also recovered well for deeply obscured high redshift sources, as well as in the absence of IR data. SED fitting is thus a powerful tool for identifying galaxies that underwent a rapid star formation quenching.
Far-Field Effects of Large Earthquakes on South Florida's Confined Aquifer

NASA Astrophysics Data System (ADS)

Voss, N. K.; Wdowinski, S.

2012-12-01

The similarity between a seismometer and a well hydraulic head record during the passage of a seismic wave has long been documented. This is true even at large distances from earthquake epicenters. South Florida lacks a dense seismic array but does contain a comparably dense network of monitoring wells. The large spatial distribution of deep monitoring wells in South Florida provides an opportunity to study the variance of aquifer response to the passage of seismic waves. We conducted a preliminary study of hydraulic head data, provided by the South Florida Water Management District, from 9 deep wells in South Florida's confined Floridian Aquifer in response to 27 main shock events (January 2010- April 2012) with magnitude 6.9 or greater. Coseismic hydraulic head response was observed in 7 of the 27 events. In order to determine what governs aquifer response to seismic events, earthquake parameters were compared for the 7 positive events. Seismic energy density (SED), an empirical relationship between distance and magnitude, was also used to compare the relative energy between the events at each well site. SED is commonly used as a parameter for establishing thresholds for hydrologic events in the near and intermediate fields. Our analysis yielded a threshold SED for well response in South Florida as 8 x 10-3 J m-3, which is consistent with other studies. Deep earthquakes, with SED above this threshold, did not appear to trigger hydraulic head oscillations. The amplitude of hydraulic head oscillations had no discernable relationship to SED levels. Preliminary results indicate a need for a modification of the SED equation to better accommodate depth in order to be of use in the study of hydrologic response in the far field. We plan to conduct a more comprehensive study incorporating a larger subset (~60) of wells in South Florida in order to further examine the spatial variance of aquifers to the passing of seismic waves as well as better confine the relationship between earthquake depth and aquifer response.
Spitzer Space Telescope Observations of Magnetic Cataclysmic Variables: Possibilities for the Presence of Dust in Polars

NASA Astrophysics Data System (ADS)

Brinkworth, C. S.; Hoard, D. W.; Wachter, S.; Howell, S. B.; Ciardi, David R.; Szkody, P.; Harrison, T. E.; van Belle, G. T.; Esin, A. A.

2007-04-01

We present Spitzer photometry of six short-period polars, EF Eri, V347 Pav, VV Pup, V834 Cen, GG Leo, and MR Ser. We have combined the Spitzer IRAC (3.6-8.0 μm) data with the 2MASS JHKs photometry to construct the SEDs of these systems from the near- to mid-IR (1.235-8 μm). We find that five out of the six polars have flux densities in the mid-IR that are substantially in excess of the values expected from the stellar components alone. We have modeled the observed SEDs with a combination of contributions from the white dwarf, secondary star, and either cyclotron emission or a cool, circumbinary dust disk to fill in the long-wavelength excess. We find that a circumbinary dust disk is the most likely cause of the 8 μm excess in all cases, but we have been unable to rule out the specific (but unlikely) case of completely optically thin cyclotron emission as the source of the observed 8 μm flux density. While both model components can generate enough flux at 8 μm, neither dust nor cyclotron emission alone can match the excess above the stellar components at all wavelengths. A model combining both cyclotron and dust contributions, possibly with some accretion-generated flux in the near-IR, is probably required, but our observed SEDs are not sufficiently well sampled to constrain such a complicated model. If the 8 μm flux density is caused by the presence of a circumbinary dust disk, then our estimates of the masses of these disks are many orders of magnitude below the mass required to affect CV evolution.
Exploring Structures and Variability in the Pre-transitional Disk in HD 169142

NASA Astrophysics Data System (ADS)

Wagner, Kevin Robert; Sitko, Michael L.; Grady, Carol A.; Whitney, Barbara; Swearingen, Jeremy R.; Champney, Elizabeth H.; Johnson, Alexa N.; Warren, Chelsea C.; Russell, Ray W.; Schneider, Glenn; Momose, Muntake; Muto, Takayuki; Inoue, Akio K.; Lauroesch, James Thomas; Hornbeck, Jeremy; Brown, Alexander; Fukagawa, Misato; Currie, Thayne M.; Wisniewski, John P.; Woodgate, Bruce E.

2015-01-01

We present a theoretical modelling analysis of of the structures in the pre-transisitonal disk in HD 169142 using 3D Monte-Carlo radiative transfer simulation. The multi-epoch broadband spectral energy distribution (SED) exhibits clear evidence of changes to the inner (sub-AU) regions of the disk over a maximum timescale of 10 years with the additional constraint that the shadowing of the outer (>25 AU) disk is non-time-dependent. We find that changes to the inner dust rim (0.2 AU) cannot account for this behavior. Instead, we find that if the inner disk posses an optically thin body of small grains then changes to the outer edge of these structures may successfully reproduce the two states in the SED (analogous to what may be occurring due to accretion onto the central star or dynamical clearing by planets). Furthermore, we explore the density distributions of the outer disk structures as they are constrained by the SED and imaged surface brightness profiles, with the conclusion that a mid-plane density power law profile of r^{-2} and r^{-1} for the 35-70 AU and 70-250 AU regions, respectively, may reproduce the observations to the limit of our available complexity of structures within our modelling software. Finally, we find that a 0.3x density scaling of the 35-70 AU region reproduces the second gap imaged in the near-infrared and at 7 mm, strengthening the link to this structure being cleared by one or more planetary mass bodies.This work was supported by NASA ADAP grant NNX09AC73G, Hubble Space Telescope grant HST-GO-13032, the IR&D program at The Aerospace Corporation, and the University of Cincinnati Honors Program.
The mechanical consequences of load bearing in the equine third metacarpal across speed and gait: the nonuniform distributions of normal strain, shear strain, and strain energy density

PubMed Central

Rubin, Clinton T.; Seeherman, Howard; Qin, Yi-Xian; Gross, Ted S.

2013-01-01

Distributions of normal strain, shear strain, and strain energy density (SED) were determined across the midshaft of the third metacarpal (MCIII, or cannon bone) of 3 adult thoroughbred horses as a function of speed and gait. A complete characterization of the mechanical demands of the bone made through the stride and from mild through the extremes of locomotion was possible by using three 3-element rosette strain gauges bonded at the diaphyseal midshaft of the MCIII and evaluating the strain output with beam theory and finite element analysis. Mean ± sd values of normal strain, shear strain, and SED increased with speed and peaked during a canter (−3560±380 microstrain, 1760±470 microstrain, and 119±23 kPa, respectively). While the location of these peaks was similar across animals and gaits, the resulting strain distributions across the cortex were consistently nonuniform, establishing between a 73-fold (slow trot) to a 330-fold (canter) disparity between the sites of maximum and minimum SED for each gait cycle. Using strain power density as an estimate of strain history across the bone revealed a 154-fold disparity between peak and minimum at the walk but fell to ∼32-fold at the canter. The nonuniform, minimally varying, strain environment suggests either that bone homeostasis is mediated by magnitude-independent mechanical signals or that the duration of stimuli necessary to establish and maintain tissue integrity is relatively brief, and thus the vast majority of strain information is disregarded.—Rubin, C. T., Seeherman, H., Qin, Y.-X., Gross, T. S., The mechanical consequences of load bearing in the equine third metacarpal across speed and gait: the nonuniform distributions of normal strain, shear strain, and strain energy density. PMID:23355269
Voluntary Running Exercise-Mediated Enhanced Neurogenesis Does Not Obliterate Retrograde Spatial Memory.

PubMed

Kodali, Maheedhar; Megahed, Tarick; Mishra, Vikas; Shuai, Bing; Hattiangady, Bharathi; Shetty, Ashok K

2016-08-03

Running exercise (RE) improves cognition, formation of anterograde memories, and mood, alongside enhancing hippocampal neurogenesis. A previous investigation in a mouse model showed that RE-induced increased neurogenesis erases retrograde memory (Akers et al., 2014). However, it is unknown whether RE-induced forgetting is common to all species. We ascertained whether voluntary RE-induced enhanced neurogenesis interferes with the recall of spatial memory in rats. Young rats assigned to either sedentary (SED) or running exercise (RE) groups were first subjected to eight learning sessions in a water maze. A probe test (PT) conducted 24 h after the final training session confirmed that animals in either group had a similar ability for the recall of short-term memory. Following this, rats in the RE group were housed in larger cages fitted with running wheels, whereas rats in the SED group remained in standard cages. Animals in the RE group ran an average of 78 km in 4 weeks. A second PT performed 4 weeks after the first PT revealed comparable ability for memory recall between animals in the RE and SED groups, which was evidenced through multiple measures of memory retrieval function. The RE group displayed a 1.5- to 2.1-fold higher hippocampal neurogenesis than SED rats. Additionally, both moderate and brisk RE did not interfere with the recall of memory, although increasing amounts of RE proportionally enhanced neurogenesis. In conclusion, RE does not impair memory recall ability in a rat model despite substantially increasing neurogenesis. Running exercise (RE) improves new memory formation along with an increased neurogenesis in the hippocampus. In view of a recent study showing that RE-mediated increased hippocampal neurogenesis promotes forgetfulness in a mouse model, we ascertained whether a similar adverse phenomenon exists in a rat model. Memory recall ability examined 4 weeks after learning confirmed that animals that had run a mean of 78 km and displayed a 1.5- to 2.1-fold increase in hippocampal neurogenesis demonstrated similar proficiency for memory recall as animals that had remained sedentary. Furthermore, both moderate and brisk RE did not interfere with memory recall, although increasing amounts of RE proportionally enhanced neurogenesis, implying that RE has no adverse effects on memory recall. Copyright © 2016 the authors 0270-6474/16/368112-11$15.00/0.
Exercise initiated after the onset of insulin resistance improves trabecular microarchitecture and cortical bone biomechanics of the tibia in hyperphagic Otsuka Long Evans Tokushima Fatty rats.

PubMed

Ortinau, Laura C; Linden, Melissa A; Dirkes, Rebecca K; Rector, R Scott; Hinton, Pamela S

2017-10-01

The present study extends our previous findings that exercise, which prevents the onset of insulin resistance and type 2 diabetes (T2D), also prevents the detrimental effects of T2D on whole-bone and tissue-level strength. Our objective was to determine whether exercise improves bone's structural and material properties if insulin resistance is already present in the Otsuka Long-Evans Tokushima Fatty (OLETF) rat. The OLETF rat is hyperphagic due to a loss-of-function mutation in cholecystokinin-1 receptor (CCK-1 receptor), which leads to progressive obesity, insulin resistance and T2D after the majority of skeletal growth is complete. Because exercise reduces body mass, which is a significant determinant of bone strength, we used a body-mass-matched caloric-restricted control to isolate body-mass-independent effects of exercise on bone. Eight-wk old, male OLETF rats were fed ad libitum until onset of hyperglycemia (20weeks of age), at which time they were randomly assigned to three groups: ad libitum fed, sedentary (O-SED); ad libitum fed, treadmill running (O-EX); or, sedentary, mild caloric restriction to match body mass of O-EX (O-CR). Long-Evans Tokushima Otsuka rats served as the normophagic, normoglycemic controls (L-SED). At 32weeks of age, O-SED rats had T2D as evidenced by hyperglycemia and a significant reduction in fasting insulin compared to OLETFs at 20weeks of age. O-SED rats also had reduced total body bone mineral content (BMC), increased C-terminal telopeptide of type I collagen (CTx)/tartrate resistant acid phosphatase isoform 5b (TRAP5b), decreased N-terminal propeptide of type I procollagen (P1NP), reduced percent cancellous bone volume (BV/TV), trabecular number (Tb.N) and increased trabecular separation (Tb.Sp) and structural model index (SMI) of the proximal tibia compared to L-SED. T2D also adversely affected biomechanical properties of the tibial diaphysis, and serum sclerostin was increased and β-catenin, runt-related transcription factor 2 (Runx2) and insulin-like growth factor-I (IGF-I) protein expression in bone were reduced in O-SED vs. L-SED. O-EX or O-CR had greater total body bone mineral density (BMD) and BMC, and BV/TV, Tb.N, Tb.Sp, and SMI compared to O-SED. O-EX had lower CTx and CR greater P1NP relative to O-SED. O-EX, not O-CR, had greater cortical thickness and area, and improved whole-bone and tissue-level biomechanical properties associated with a 4-fold increase in cortical bone β-catenin protein expression vs. O-SED. In summary, EX or CR initiated after the onset of insulin resistance preserved cancellous bone volume and structure, and EX elicited additional benefits in cortical bone. Copyright © 2017 Elsevier Inc. All rights reserved.
EVOLUTION OF GALAXIES AND THEIR ENVIRONMENTS AT z = 0.1-3 IN COSMOS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scoville, N.; Benson, A.; Fu, Hai

2013-05-01

Large-scale structures (LSSs) out to z < 3.0 are measured in the Cosmic Evolution Survey (COSMOS) using extremely accurate photometric redshifts (photoz). The K{sub s} -band-selected sample (from Ultra-Vista) is comprised of 155,954 galaxies. Two techniques-adaptive smoothing and Voronoi tessellation-are used to estimate the environmental densities within 127 redshift slices. Approximately 250 statistically significant overdense structures are identified out to z = 3.0 with shapes varying from elongated filamentary structures to more circularly symmetric concentrations. We also compare the densities derived for COSMOS with those based on semi-analytic predictions for a {Lambda}CDM simulation and find excellent overall agreement between themore » mean densities as a function of redshift and the range of densities. The galaxy properties (stellar mass, spectral energy distributions (SEDs), and star formation rates (SFRs)) are strongly correlated with environmental density and redshift, particularly at z < 1.0-1.2. Classifying the spectral type of each galaxy using the rest-frame b - i color (from the photoz SED fitting), we find a strong correlation of early-type galaxies (E-Sa) with high-density environments, while the degree of environmental segregation varies systematically with redshift out to z {approx} 1.3. In the highest density regions, 80% of the galaxies are early types at z = 0.2 compared to only 20% at z = 1.5. The SFRs and the star formation timescales exhibit clear environmental correlations. At z > 0.8, the SFR density is uniformly distributed over all environmental density percentiles, while at lower redshifts the dominant contribution is shifted to galaxies in lower density environments.« less
INTERPRETING FLUX FROM BROADBAND PHOTOMETRY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Peter J.; Breeveld, Alice; Roming, Peter W. A.

2016-10-01

We discuss the transformation of observed photometry into flux for the creation of spectral energy distributions (SED) and the computation of bolometric luminosities. We do this in the context of supernova studies, particularly as observed with the Swift spacecraft, but the concepts and techniques should be applicable to many other types of sources and wavelength regimes. Traditional methods of converting observed magnitudes to flux densities are not very accurate when applied to UV photometry. Common methods for extinction and the integration of pseudo-bolometric fluxes can also lead to inaccurate results. The sources of inaccuracy, though, also apply to other wavelengths.more » Because of the complicated nature of translating broadband photometry into monochromatic flux densities, comparison between observed photometry and a spectroscopic model is best done by forward modeling the spectrum into the count rates or magnitudes of the observations. We recommend that integrated flux measurements be made using a spectrum or SED which is consistent with the multi-band photometry rather than converting individual photometric measurements to flux densities, linearly interpolating between the points, and integrating. We also highlight some specific areas where the UV flux can be mischaracterized.« less
Computational network model prediction of hemodynamic alterations due to arteriolar remodeling in interval sprint trained skeletal muscle.

PubMed

Binder, Kyle W; Murfee, Walter L; Song, Ji; Laughlin, M Harold; Price, Richard J

2007-01-01

Exercise training is known to enhance skeletal muscle blood flow capacity, with high-intensity interval sprint training (IST) primarily affecting muscles with a high proportion of fast twitch glycolytic fibers. The objective of this study was to determine the relative contributions of new arteriole formation and lumenal arteriolar remodeling to enhanced flow capacity and the impact of these adaptations on local microvascular hemodynamics deep within the muscle. The authors studied arteriolar adaptation in the white/mixed-fiber portion of gastrocnemius muscles of IST (6 bouts of running/day; 2.5 min/bout; 60 m/min speed; 15% grade; 4.5 min rest between bouts; 5 training days/wk; 10 wks total) and sedentary (SED) control rats using whole-muscle Microfil casts. Dimensional and topological data were then used to construct a series of computational hemodynamic network models that incorporated physiological red blood cell distributions and hematocrit and diameter dependent apparent viscosities. In comparison to SED controls, IST elicited a significant increase in arterioles/order in the 3A through 6A generations. Predicted IST and SED flows through the 2A generation agreed closely with in vivo measurements made in a previous study, illustrating the accuracy of the model. IST shifted the bulk of the pressure drop across the network from the 3As to the 4As and 5As, and flow capacity increased from 0.7 mL/min in SED to 1.5 mL/min in IST when a driving pressure of 80 mmHg was applied. The primary adaptation to IST is an increase in arterioles in the 3A through 6A generations, which, in turn, creates an approximate doubling of flow capacity and a deeper penetration of high pressure into the arteriolar network.
SED-ED, a workflow editor for computational biology experiments written in SED-ML.

PubMed

Adams, Richard R

2012-04-15

The simulation experiment description markup language (SED-ML) is a new community data standard to encode computational biology experiments in a computer-readable XML format. Its widespread adoption will require the development of software support to work with SED-ML files. Here, we describe a software tool, SED-ED, to view, edit, validate and annotate SED-ML documents while shielding end-users from the underlying XML representation. SED-ED supports modellers who wish to create, understand and further develop a simulation description provided in SED-ML format. SED-ED is available as a standalone Java application, as an Eclipse plug-in and as an SBSI (www.sbsi.ed.ac.uk) plug-in, all under an MIT open-source license. Source code is at https://sed-ed-sedmleditor.googlecode.com/svn. The application itself is available from https://sourceforge.net/projects/jlibsedml/files/SED-ED/.
Process parameters and morphology in puerarin, phospholipids and their complex microparticles generation by supercritical antisolvent precipitation.

PubMed

Li, Ying; Yang, Da-Jian; Chen, Shi-Lin; Chen, Si-Bao; Chan, Albert Sun-Chi

2008-07-09

The aim of the study was to develop and evaluate a new method for the production of puerarin phospholipids complex (PPC) microparticles. The advanced particle formation method, solution enhanced dispersion by supercritical fluids (SEDS), was used for the preparation of puerarin (Pur), phospholipids (PC) and their complex particles for the first time. Evaluation of the processing variables on PPC particle characteristics was also conducted. The processing variables included temperature, pressure, solution concentration, the flow rate of supercritical carbon dioxide (SC-CO2) and the relative flow rate of drug solution to CO2. The morphology, particle size and size distribution of the particles were determined. Meanwhile Pur and phospholipids were separately prepared by gas antisolvent precipitation (GAS) method and solid characterization of particles by the two supercritical methods was also compared. Pur formed by GAS was more orderly, purer crystal, whereas amorphous Pur particles between 0.5 and 1microm were formed by SEDS. The complex was successfully obtained by SEDS exhibiting amorphous, partially agglomerated spheres comprised of particles sized only about 1microm. SEDS method may be useful for the processing of other pharmaceutical preparations besides phospholipids complex particles. Furthermore adopting a GAS process to recrystallize pharmaceuticals will provide a highly versatile methodology to generate new polymorphs of drugs in addition to conventional techniques.
Supercritical carbon dioxide-developed silk fibroin nanoplatform for smart colon cancer therapy.

PubMed

Xie, Maobin; Fan, Dejun; Li, Yi; He, Xiaowen; Chen, Xiaoming; Chen, Yufeng; Zhu, Jixiang; Xu, Guibin; Wu, Xiaojian; Lan, Ping

2017-01-01

To deliver insoluble natural compounds into colon cancer cells in a controlled fashion. Curcumin (CM)-silk fibroin (SF) nanoparticles (NPs) were prepared by solution-enhanced dispersion by supercritical CO 2 (SEDS) (20 MPa pressure, 1:2 CM:SF ratio, 1% concentration), and their physicochemical properties, intracellular uptake efficiency, in vitro anticancer effect, toxicity, and mechanisms were evaluated and analyzed. CM-SF NPs (<100 nm) with controllable particle size were prepared by SEDS. CM-SF NPs had a time-dependent intracellular uptake ability, which led to an improved inhibition effect on colon cancer cells. Interestingly, the anticancer effect of CM-SF NPs was improved, while the side effect on normal human colon mucosal epithelial cells was reduced by a concentration of ~10 μg/mL. The anticancer mechanism involves cell-cycle arrest in the G 0 /G 1 and G 2 /M phases in association with inducing apoptotic cells. The natural compound-loaded SF nanoplatform prepared by SEDS indicates promising colon cancer-therapy potential.
Myocardial hypoperfusion/reperfusion tolerance with exercise training in hypertension.

PubMed

Reger, Patricia O; Barbe, Mary F; Amin, Mamta; Renna, Brian F; Hewston, Leigh Ann; MacDonnell, Scott M; Houser, Steven R; Libonati, Joseph R

2006-02-01

The purpose of this study was to examine whether exercise training, superimposed on compensated-concentric hypertrophy, could increase myocardial hypoperfusion-reperfusion (H/R) tolerance. Female Wistar-Kyoto rats (WKY) and spontaneously hypertensive rats (SHR) (age: 4 mo; N = 40) were placed into a sedentary (SED) or exercise training (TRD) group (treadmill running; 25 m/min, 1 h/day, 5 days/wk for 16 wk). Four groups were studied: WKY-SED (n = 10), WKY-TRD (n = 10), SHR-SED (n = 10), and SHR-TRD (n = 10). Blood pressure and heart rate were determined, and in vitro isolated heart performance was measured with a retrogradely perfused, Langendorff isovolumic preparation. The H/R protocol consisted of a 75% reduction in coronary flow for 17 min followed by 30 min of reperfusion. Although the rate-pressure product was significantly elevated in SHR relative to WKY, training-induced bradycardia reduced the rate-pressure product in SHR-TRD (P < 0.05) without an attenuation in systolic blood pressure. Heart-to-body weight ratio was greater in both groups of SHR vs. WKY-SED (P < 0.001). Absolute and relative myocardial tolerance to H/R was greater in WKY-TRD and both groups of SHR relative to WKY-SED (P < 0.05). Endurance training superimposed on hypertension-induced compensated hypertrophy conferred no further cardioprotection to H/R. Postreperfusion 72-kDa heat shock protein abundance was enhanced in WKY-TRD and both groups of SHR relative to WKY-SED (P < 0.05) and was highly correlated with absolute left ventricular functional recovery during reperfusion (R2= 0.86, P < 0.0001). These data suggest that both compensated hypertrophy associated with short-term hypertension and endurance training individually improved H/R and that increased postreperfusion 72-kDa heat shock protein abundance was, in part, associated with the cardioprotective phenotype observed in this study.
Identification of burrowing shrimp food sources along an estuarine gradient using fatty acid analysis and stable isotope ratios

USDA-ARS?s Scientific Manuscript database

Two species of burrowing shrimps occur in high densities in U.S. West Coast estuaries, the ghost shrimp (Neotrypaea californiensis) and the blue mud shrimp (Upogebia pugettensis). Both species of shrimp are considered ecosystem engineers as they bioturbate and irrigate extensive galleries in the sed...
Estimation of Local Bone Loads for the Volume of Interest.

PubMed

Kim, Jung Jin; Kim, Youkyung; Jang, In Gwun

2016-07-01

Computational bone remodeling simulations have recently received significant attention with the aid of state-of-the-art high-resolution imaging modalities. They have been performed using localized finite element (FE) models rather than full FE models due to the excessive computational costs of full FE models. However, these localized bone remodeling simulations remain to be investigated in more depth. In particular, applying simplified loading conditions (e.g., uniform and unidirectional loads) to localized FE models have a severe limitation in a reliable subject-specific assessment. In order to effectively determine the physiological local bone loads for the volume of interest (VOI), this paper proposes a novel method of estimating the local loads when the global musculoskeletal loads are given. The proposed method is verified for the three VOI in a proximal femur in terms of force equilibrium, displacement field, and strain energy density (SED) distribution. The effect of the global load deviation on the local load estimation is also investigated by perturbing a hip joint contact force (HCF) in the femoral head. Deviation in force magnitude exhibits the greatest absolute changes in a SED distribution due to its own greatest deviation, whereas angular deviation perpendicular to a HCF provides the greatest relative change. With further in vivo force measurements and high-resolution clinical imaging modalities, the proposed method will contribute to the development of reliable patient-specific localized FE models, which can provide enhanced computational efficiency for iterative computing processes such as bone remodeling simulations.

Broadband spectral fitting of blazars using XSPEC

NASA Astrophysics Data System (ADS)

Sahayanathan, Sunder; Sinha, Atreyee; Misra, Ranjeev

2018-03-01

The broadband spectral energy distribution (SED) of blazars is generally interpreted as radiation arising from synchrotron and inverse Compton mechanisms. Traditionally, the underlying source parameters responsible for these emission processes, like particle energy density, magnetic field, etc., are obtained through simple visual reproduction of the observed fluxes. However, this procedure is incapable of providing confidence ranges for the estimated parameters. In this work, we propose an efficient algorithm to perform a statistical fit of the observed broadband spectrum of blazars using different emission models. Moreover, we use the observable quantities as the fit parameters, rather than the direct source parameters which govern the resultant SED. This significantly improves the convergence time and eliminates the uncertainty regarding initial guess parameters. This approach also has an added advantage of identifying the degenerate parameters, which can be removed by including more observable information and/or additional constraints. A computer code developed based on this algorithm is implemented as a user-defined routine in the standard X-ray spectral fitting package, XSPEC. Further, we demonstrate the efficacy of the algorithm by fitting the well sampled SED of blazar 3C 279 during its gamma ray flare in 2014.
Early science from the Pan-STARRS1 Optical Galaxy Survey (POGS): Maps of stellar mass and star formation rate surface density obtained from distributed-computing pixel-SED fitting

NASA Astrophysics Data System (ADS)

Thilker, David A.; Vinsen, K.; Galaxy Properties Key Project, PS1

2014-01-01

To measure resolved galactic physical properties unbiased by the mask of recent star formation and dust features, we are conducting a citizen-scientist enabled nearby galaxy survey based on the unprecedented optical (g,r,i,z,y) imaging from Pan-STARRS1 (PS1). The PS1 Optical Galaxy Survey (POGS) covers 3π steradians (75% of the sky), about twice the footprint of SDSS. Whenever possible we also incorporate ancillary multi-wavelength image data from the ultraviolet (GALEX) and infrared (WISE, Spitzer) spectral regimes. For each cataloged nearby galaxy with a reliable redshift estimate of z < 0.05 - 0.1 (dependent on donated CPU power), publicly-distributed computing is being harnessed to enable pixel-by-pixel spectral energy distribution (SED) fitting, which in turn provides maps of key physical parameters such as the local stellar mass surface density, crude star formation history, and dust attenuation. With pixel SED fitting output we will then constrain parametric models of galaxy structure in a more meaningful way than ordinarily achieved. In particular, we will fit multi-component (e.g. bulge, bar, disk) galaxy models directly to the distribution of stellar mass rather than surface brightness in a single band, which is often locally biased. We will also compute non-parametric measures of morphology such as concentration, asymmetry using the POGS stellar mass and SFR surface density images. We anticipate studying how galactic substructures evolve by comparing our results with simulations and against more distant imaging surveys, some of which which will also be processed in the POGS pipeline. The reliance of our survey on citizen-scientist volunteers provides a world-wide opportunity for education. We developed an interactive interface which highlights the science being produced by each volunteer’s own CPU cycles. The POGS project has already proven popular amongst the public, attracting about 5000 volunteers with nearly 12,000 participating computers, and is growing rapidly.
Abnormal distribution of low-latitude ionospheric electron density during November 2004 superstorm as reconstructed by 3-D CT technique from IGS and LEO/GPS observations

NASA Astrophysics Data System (ADS)

Xiao, R.; Ma, S.; Xu, J.; Xiong, C.; Yan, W.; Luhr, H.; Jakowski, N.

2010-12-01

Using time-dependent 3-D tomography method, the electron density distributions in the mid- and low-latitude ionosphere are reconstructed from GPS observations of joint ground-based IGS network and onboard CHAMP/GRACE satellites during November 2004 super-storm. For LEO satellite-based GPS receiving, both the occultation TEC data and that along the radio propagation paths above the LEO are used. The electron density images versus latitude/altitude/longitude are reconstructed for different sectors of America/Asia/Europe and produced every hour. The reconstructed electron densities are validated by satellite in situ measurements of CHAMP Langmuir probe and GRACE Ka-band SST (low-low satellite-to-satellite tracking) derived electron density averaged between the two satellites, as well as by CIT simulations. It reveals some very interesting storm-time structures of Ne distributions, such as top-hat-like F2-3 double layer and column-like enhanced electron densities (CEED). The double layer structure appeared over a large latitude range from about -30 degree to 20 degree along East-Asian/Australia longitudes before local noon, looking like one additional smaller EIA structure standing above the usual one of EIA. It is consistent with the F-3 layer observed by ionosonde at an Australian low-latitude station. The CEED are found just 1-2 hours before the minimum of Dst and in the longitudinal sector about 157 E. They extend from the topside ionosphere toward plasmasphere, reaching at least about 2000 km as high. Their footprints stand on the two peaks of the EIA. This CEED is also seen in the image of 30.4 nm He ++ radiation by IMAGE, showing a narrow channel of enhanced density extending from afternoon ionosphere to plasmsphere westward. The forming mechanism of CEED and its relationship with SED and plasmaspheric plumes are worthy of further study. Acknowledgement: This work is supported by NSFC (No.40674078).
SEDS experiment design definition

NASA Technical Reports Server (NTRS)

Carroll, Joseph A.; Alexander, Charles M.; Oldson, John C.

1990-01-01

The Small Expendable-tether Deployment System (SEDS) was developed to design, build, integrate, fly, and safely deploy and release an expendable tether. A suitable concept for an on-orbit test of SEDS was developed. The following tasks were performed: (1) Define experiment objectives and requirements; (2) Define experiment concepts to reach those objectives; (3) Support NASA in experiment concept selection and definition; (4) Perform analyses and tests of SEDS hardware; (5) Refine the selected SEDS experiment concept; and (6) Support interactive SEDS system definition process. Results and conclusions are given.
Effect of milking frequency and diet on milk production, energy balance, and reproduction in dairy cows.

PubMed

Patton, J; Kenny, D A; Mee, J F; O'Mara, F P; Wathes, D C; Cook, M; Murphy, J J

2006-05-01

The objective of this study was to determine the effects of reduced milking frequency and increased dietary energy density in early lactation on milk production, energy balance, and subsequent fertility. Sixty-six spring-calving, multiparous Holstein-Friesian cows were assigned to 1 of 3 treatment groups: once-daily milking on a standard diet (1xST); 3-times daily milking on a standard diet (3xST); and 3-times daily milking on a high-energy diet. Treatments were imposed for the first 28 d of lactation, after which all groups were milked twice daily and fed the standard diet. During the treatment period, the 1xST cows had 19.6% lower milk yield and higher milk fat and milk protein concentrations (15.7 and 10.2%, respectively) compared with 3xST. Dry matter (DM) intake was similar between 1xST and 3xST during the treatment period (12.64 vs. 13.25 kg/ d; SED = 0.82). Daily energy balance was less negative for 1xST compared with 3xST during wk 1 to 3 of lactation [-3.92 vs. -5.30 unité fourragère lait (UFL)/d; SED = 0.65; 1 UFL is equal to the net energy for lactation of 1 kg of standard air-dry barley]. During the treatment period, the cows on the high-energy diet had 17% higher milk yield, higher DM intake (15.5 vs. 13.9 kg/d; SED = 0.71), and similar energy balance (-4.45 vs. -4.35 UFL/d; SED = 0.65) compared to 3xST. Diet had no significant effect on any of the fertility variables measured. The interval to first ovulation was shorter for 1xST than 3xST (18.3d vs. 28.6d; SED = 1.76). In conclusion, once-daily milking in early lactation may promote earlier resumption of ovarian cyclicity, mediated through improved nutritional status.
Investigation on Consumers’ Behaviour towards Energy Saving through Utilisation of Virtual SED (Smart Energy Displays) in Residential Building

NASA Astrophysics Data System (ADS)

Adlisia Puspa Harani, Sandhika

2018-05-01

The study is conducted by gathering data from interviews an in-home experiment, to examine the impacts of both virtual and physical SED toward user engagement. Business opportunity and benefits of virtual SED for stake holders are also discussed in this study. The research was conducted by interviewing method to respondens in Nottingham, UK. By comparing consumers’ energy saving behaviour from physical and virtual SED users, virtual SED shows similar level of effectiveness as physical SED, but there is no evidence that the virtual versions are better than the physical ones in terms of reducing energy consumption. Nevertheless, virtual SED can be more beneficial for consumers who can get easier access. They also help educating users to be more concern about energy issue. Energy suppliers get benefits by having virtual versions of SED, in which they can reduce production and distribution costs, as well as diminishing waste from physical SED.
Supercritical carbon dioxide-developed silk fibroin nanoplatform for smart colon cancer therapy

PubMed Central

Li, Yi; He, Xiaowen; Chen, Xiaoming; Chen, Yufeng; Zhu, Jixiang; Xu, Guibin; Wu, Xiaojian; Lan, Ping

2017-01-01

Purpose To deliver insoluble natural compounds into colon cancer cells in a controlled fashion. Materials and methods Curcumin (CM)–silk fibroin (SF) nanoparticles (NPs) were prepared by solution-enhanced dispersion by supercritical CO2 (SEDS) (20 MPa pressure, 1:2 CM:SF ratio, 1% concentration), and their physicochemical properties, intracellular uptake efficiency, in vitro anticancer effect, toxicity, and mechanisms were evaluated and analyzed. Results CM-SF NPs (<100 nm) with controllable particle size were prepared by SEDS. CM-SF NPs had a time-dependent intracellular uptake ability, which led to an improved inhibition effect on colon cancer cells. Interestingly, the anticancer effect of CM-SF NPs was improved, while the side effect on normal human colon mucosal epithelial cells was reduced by a concentration of ~10 μg/mL. The anticancer mechanism involves cell-cycle arrest in the G0/G1 and G2/M phases in association with inducing apoptotic cells. Conclusion The natural compound-loaded SF nanoplatform prepared by SEDS indicates promising colon cancer-therapy potential. PMID:29118580
Computational Network Model Prediction of Hemodynamic Alterations Due to Arteriolar Remodeling in Interval Sprint Trained Skeletal Muscle

PubMed Central

BINDER, KYLE W.; MURFEE, WALTER L.; SONG, JI; LAUGHLIN, M. HAROLD; PRICE, RICHARD J.

2009-01-01

Objectives Exercise training is known to enhance skeletal muscle blood flow capacity, with high-intensity interval sprint training (IST) primarily affecting muscles with a high proportion of fast twitch glycolytic fibers. The objective of this study was to determine the relative contributions of new arteriole formation and lumenal arteriolar remodeling to enhanced flow capacity and the impact of these adaptations on local microvascular hemodynamics deep within the muscle. Methods The authors studied arteriolar adaptation in the white/mixed-fiber portion of gastrocnemius muscles of IST (6 bouts of running/day; 2.5 min/bout; 60 m/min speed; 15% grade; 4.5 min rest between bouts; 5 training days/wk; 10 wks total) and sedentary (SED) control rats using whole-muscle Microfil casts. Dimensional and topological data were then used to construct a series of computational hemodynamic network models that incorporated physiological red blood cell distributions and hematocrit and diameter dependent apparent viscosities. Results In comparison to SED controls, IST elicited a significant increase in arterioles/order in the 3A through 6A generations. Predicted IST and SED flows through the 2A generation agreed closely with in vivo measurements made in a previous study, illustrating the accuracy of the model. IST shifted the bulk of the pressure drop across the network from the 3As to the 4As and 5As, and flow capacity increased from 0.7 mL/min in SED to 1.5 mL/min in IST when a driving pressure of 80 mmHg was applied. Conclusions The primary adaptation to IST is an increase in arterioles in the 3A through 6A generations, which, in turn, creates an approximate doubling of flow capacity and a deeper penetration of high pressure into the arteriolar network. PMID:17454671
SedMob: A mobile application for creating sedimentary logs in the field

NASA Astrophysics Data System (ADS)

Wolniewicz, Pawel

2014-05-01

SedMob is an open-source, mobile software package for creating sedimentary logs, targeted for use in tablets and smartphones. The user can create an unlimited number of logs, save data from each bed in the log as well as export and synchronize the data with a remote server. SedMob is designed as a mobile interface to SedLog: a free multiplatform package for drawing graphic logs that runs on PC computers. Data entered into SedMob are saved in the CSV file format, fully compatible with SedLog.
Propierties of dust in circumstellar gas around Wolf-Rayet stars

NASA Astrophysics Data System (ADS)

Jiménez-Hernández, P.; Arthur, S. J.; Toalá, J. A.

2017-11-01

Using archive photometric observations from Herschel (70μm, 100μm, 160μm and 250μm), Spitzer (24μm) and WISE (22μm and 12μm) we obtained infrared SED's of nebulae around the Wolf-Rayet stars WR 124, WR 16 and WR 7. We used the photoionization code Cloudy to construct models of the nebulae, taking into account the spectrum of the central star and varying the density and distance of the photoionized shell as well as the size distribution and chemical composition of the dust grains mixed with the gas, and we compared the resulting SEDs with the observations in order to study the properties of the dust in these objects. We discuss whether the dust properties depend on the spectral type of the central star and the age of the nebulae.
SPECTRAL ENERGY DISTRIBUTIONS OF TYPE 1 ACTIVE GALACTIC NUCLEI IN THE COSMOS SURVEY. I. THE XMM-COSMOS SAMPLE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elvis, M.; Hao, H.; Civano, F.

2012-11-01

The 'Cosmic Evolution Survey' (COSMOS) enables the study of the spectral energy distributions (SEDs) of active galactic nuclei (AGNs) because of the deep coverage and rich sampling of frequencies from X-ray to radio. Here we present an SED catalog of 413 X-ray (XMM-Newton)-selected type 1 (emission line FWHM > 2000 km s{sup -1}) AGNs with Magellan, SDSS, or VLT spectrum. The SEDs are corrected for Galactic extinction, broad emission line contributions, constrained variability, and host galaxy contribution. We present the mean SED and the dispersion SEDs after the above corrections in the rest-frame 1.4 GHz to 40 keV, and showmore » examples of the variety of SEDs encountered. In the near-infrared to optical (rest frame {approx}8 {mu}m-4000 A), the photometry is complete for the whole sample and the mean SED is derived from detections only. Reddening and host galaxy contamination could account for a large fraction of the observed SED variety. The SEDs are all available online.« less
Multiwavelength Variations of 3C 454.3 during the 2010 November to 2011 January Outburst

NASA Astrophysics Data System (ADS)

Wehrle, Ann E.; Marscher, Alan P.; Jorstad, Svetlana G.; Gurwell, Mark A.; Joshi, Manasvita; MacDonald, Nicholas R.; Williamson, Karen E.; Agudo, Iván; Grupe, Dirk

2012-10-01

We present multiwavelength data of the blazar 3C 454.3 obtained during an extremely bright outburst from 2010 November through 2011 January. These include flux density measurements with the Herschel Space Observatory at five submillimeter-wave and far-infrared bands, the Fermi Large Area Telescope at γ-ray energies, Swift at X-ray, ultraviolet (UV), and optical frequencies, and the Submillimeter Array at 1.3 mm. From this data set, we form a series of 52 spectral energy distributions (SEDs) spanning nearly two months that are unprecedented in time coverage and breadth of frequency. Discrete correlation analysis of the millimeter, far-infrared, and γ-ray light curves show that the variations were essentially simultaneous, indicative of cospatiality of the emission, at these wavebands. In contrast, differences in short-term fluctuations at various wavelengths imply the presence of inhomogeneities in physical conditions across the source. We locate the site of the outburst in the parsec-scale "core," whose flux density as measured on 7 mm Very Long Baseline Array images increased by 70% during the first five weeks of the outburst. Based on these considerations and guided by the SEDs, we propose a model in which turbulent plasma crosses a conical standing shock in the parsec-scale region of the jet. Here, the high-energy emission in the model is produced by inverse Compton scattering of seed photons supplied by either nonthermal radiation from a Mach disk, thermal emission from hot dust, or (for X-rays) synchrotron radiation from plasma that crosses the standing shock. For the two dates on which we fitted the model SED to the data, the model corresponds very well to the observations at all bands except at X-ray energies, where the spectrum is flatter than observed.
Social experiential deprivation in autism spectrum disorders: A possible prognostic factor?

PubMed

Kaku, Sowmyashree Mayur; Basheer, Salah; Venkatasubramanian, Ganesan; Bharath, Rose Dawn; Girimaji, Satish Chandra; Srinath, Shoba

2017-04-01

Autism spectrum disorders (ASD) are well known to be influenced by various environmental factors. Among these influencers, social experiential deprivation (SED) in infancy is one of them which is not well reported. We explored factors contributing to SED in 11 young children diagnosed to have ASD and compared them to 24 children without SED also having ASD. Intervention mainly addressing factors causing SED for 6 months demonstrated that children with SED had a better outcome at follow up. Could SED be a possible prognostic factor in children with ASD? Copyright © 2017 Elsevier B.V. All rights reserved.
Column-like EED extending from equatorial topside ionosphere toward plasmasphere retrieved from IGS and LEO/GPS observations with 3-D CT inversion

NASA Astrophysics Data System (ADS)

Xiao, R.; Ma, S. Y.; Xu, J. S.; Xiong, C.; Luehr, H.; Jakowski, N.

2010-05-01

The electron density distributions in the equatorial ionosphere are retrieved from GPS observations of joint ground-based IGS and onboard CHAMP/GRACE satellites during November 2004 super-storm by 3-D tomography technique. For LEO satellite-based GPS receiving, both the occultation TEC data and that along the radio propagation paths above the LEO are used and assimilated into the huge IGS TEC dataset. The electron density images are reconstructed for different sectors of America, Asia and Europe and produced for every hour. The retrieved electron densities are validated by satellite in situ measurements of CHAMP Langmuir probe and GRACE Ka-band SST (low-low satellite-to-satellite tracking) derived electron density averaged between the two satellites, as well as by numerical simulations. It reveals some very interesting storm-time structures of Ne distributions, such as top-hat-like F2-3 double layer and column-like enhanced electron densities (CEED). The CEED are found during the main phase of the storm near the minimum of Dst and in the longitudinal sector centered at 157E. They extend from the topside ionosphere toward to plasmasphere, reaching at least about 2000 km as high. The footprints of the CEED stand on the two peaks of the EIA. The forming mechanism of CEED and its relationship with SED and plasmaspheric plumes are worthy of further study. This work is supported by NSFC (No.40674078).
Spatially unresolved SED fitting can underestimate galaxy masses: a solution to the missing mass problem

NASA Astrophysics Data System (ADS)

Sorba, Robert; Sawicki, Marcin

2018-05-01

We perform spatially resolved, pixel-by-pixel Spectral Energy Distribution (SED) fitting on galaxies up to z ˜ 2.5 in the Hubble eXtreme Deep Field (XDF). Comparing stellar mass estimates from spatially resolved and spatially unresolved photometry we find that unresolved masses can be systematically underestimated by factors of up to 5. The ratio of the unresolved to resolved mass measurement depends on the galaxy's specific star formation rate (sSFR): at low sSFRs the bias is small, but above sSFR ˜ 10-9.5 yr-1 the discrepancy increases rapidly such that galaxies with sSFRs ˜ 10-8 yr-1 have unresolved mass estimates of only one-half to one-fifth of the resolved value. This result indicates that stellar masses estimated from spatially unresolved data sets need to be systematically corrected, in some cases by large amounts, and we provide an analytic prescription for applying this correction. We show that correcting stellar mass measurements for this bias changes the normalization and slope of the star-forming main sequence and reduces its intrinsic width; most dramatically, correcting for the mass bias increases the stellar mass density of the Universe at high redshift and can resolve the long-standing discrepancy between the directly measured cosmic SFR density at z ≳ 1 and that inferred from stellar mass densities (`the missing mass problem').
AzTEC Survey of the Central Molecular Zone: Modeling Dust SEDs and N-PDF with Hierarchical Bayesian Analysis

NASA Astrophysics Data System (ADS)

Tang, Yuping; Wang, Daniel; Wilson, Grant; Gutermuth, Robert; Heyer, Mark

2018-01-01

We present the AzTEC/LMT survey of dust continuum at 1.1mm on the central ˜ 200pc (CMZ) of our Galaxy. A joint SED analysis of all existing dust continuum surveys on the CMZ is performed, from 160µm to 1.1mm. Our analysis follows a MCMC sampling strategy incorporating the knowledge of PSFs in different maps, which provides unprecedented spacial resolution on distributions of dust temperature, column density and emissivity index. The dense clumps in the CMZ typically show low dust temperature ( 20K), with no significant sign of buried star formation, and a weak evolution of higher emissivity index toward dense peak. A new model is proposed, allowing for varying dust temperature inside a cloud and self-shielding of dust emission, which leads to similar conclusions on dust temperature and grain properties. We further apply a hierarchical Bayesian analysis to infer the column density probability distribution function (N-PDF), while simultaneously removing the Galactic foreground and background emission. The N-PDF shows a steep power-law profile with α > 3, indicating that formation of dense structures are suppressed.
Arabidopsis mitochondrial protein slow embryo development1 is essential for embryo development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ju, Yan; Liu, Chunying; Lu, Wenwen

The plant seeds formation are crucial parts in reproductive process in seed plants as well as food source for humans. Proper embryo development ensure viable seed formation. Here, we showed an Arabidopsis T-DNA insertion mutant slow embryo development1 (sed1) which exhibited retarded embryogenesis, led to aborted seeds. Embryo without SED1 developed slower compared to normal one and could be recognized at early globular stage by its white appearance. In later development stage, storage accumulated poorly with less protein and lipid body production. In vitro culture did not rescue albino embryo. SED1 encoded a protein targeted to mitochondria. Transmission electron microscopic analysismore » revealed that mitochondria developed abnormally, and more strikingly plastid failed to construct grana in time in sed1/sed1 embryo. These data indicated that SED1 is indispensable for embryogenesis in Arabidopsis, and the mitochondria may be involved in the regulation of many aspects of seed development. -- Highlights: •Arabidopsis SED1 is essential for embryo development. •The sed1 embryo accumulates less storage and has abnormal ultrastructure. •SED1 localizes to the mitochondrion.« less
3C 279 IN OUTBURST IN 2015 JUNE: A BROADBAND SED STUDY BASED ON THE INTEGRAL DETECTION

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bottacini, Eugenio; Böttcher, Markus; Pian, Elena

2016-11-20

Blazars radiate from radio through gamma-ray frequencies and thereby make ideal targets for multifrequency studies. Such studies allow the properties of the emitting jet to be constrained. 3C 279 is among the most notable blazars and therefore subject to extensive multifrequency campaigns. We report the results of a campaign ranging from near-IR to gamma-ray energies that targeted an outburst of 3C 279 in 2015 June. The campaign pivots around the detection in only 50 ks by INTEGRAL , whose IBIS/ISGRI data pin down the high-energy component of the spectral energy distribution (SED) between Swift -XRT data and Fermi -LAT data. The overallmore » SED from near-IR to gamma rays can be well represented by either a leptonic or a lepto-hadronic radiation transfer model. Even though the data are equally well represented by the two models, their inferred parameters challenge the physical conditions in the jet. In fact, the leptonic model requires parameters with a magnetic field far below equipartition with the relativistic particle energy density. In contrast, equipartition may be achieved with the lepto-hadronic model, although this implies an extreme total jet power close to the Eddington luminosity.« less
Experimental study of NO2 reduction in N2/Ar and O2/Ar mixtures by pulsed corona discharge.

PubMed

Zhu, Xinbo; Zheng, Chenghang; Gao, Xiang; Shen, Xu; Wang, Zhihua; Luo, Zhongyang; Cen, Kefa

2014-11-01

Non-thermal plasma technology has been regarded as a promising alternative technology for NOx removal. The understanding of NO2 reduction characteristics is extremely important since NO2 reduction could lower the total NO oxidation rate in the plasma atmosphere. In this study, NO2 reduction was experimentally investigated using a non-thermal plasma reactor driven by a pulsed power supply for different simulated gas compositions and operating parameters. The NO2 reduction was promoted by increasing the specific energy density (SED), and the highest conversion rates were 33.7%, 42.1% and 25.7% for Ar, N2/Ar and O2/Ar, respectively. For a given SED, the NO2 conversion rate had the order N2/Ar>Ar>O2/Ar. The highest energy yield of 3.31g/kWh was obtained in N2/Ar plasma and decreased with increasing SED; the same trends were also found in the other two gas compositions. The conversion rate decreased with increasing initial NO2 concentration. Furthermore, the presence of N2 or O2 led to different reaction pathways for NO2 conversion due to the formation of different dominating reactive radicals. Copyright © 2014. Published by Elsevier B.V.
THE ENVIRONMENT AND DISTRIBUTION OF EMITTING ELECTRONS AS A FUNCTION OF SOURCE ACTIVITY IN MARKARIAN 421

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mankuzhiyil, Nijil; Ansoldi, Stefano; Persic, Massimo

2011-05-20

For the high-frequency-peaked BL Lac object Mrk 421, we study the variation of the spectral energy distribution (SED) as a function of source activity, from quiescent to active. We use a fully automatized {chi}{sup 2}-minimization procedure, instead of the 'eyeball' procedure more commonly used in the literature, to model nine SED data sets with a one-zone synchrotron self-Compton (SSC) model and examine how the model parameters vary with source activity. The latter issue can finally be addressed now, because simultaneous broadband SEDs (spanning from optical to very high energy photon) have finally become available. Our results suggest that in Mrkmore » 421 the magnetic field (B) decreases with source activity, whereas the electron spectrum's break energy ({gamma}{sub br}) and the Doppler factor ({delta}) increase-the other SSC parameters turn out to be uncorrelated with source activity. In the SSC framework, these results are interpreted in a picture where the synchrotron power and peak frequency remain constant with varying source activity, through a combination of decreasing magnetic field and increasing number density of {gamma} {<=} {gamma}{sub br} electrons: since this leads to an increased electron-photon scattering efficiency, the resulting Compton power increases, and so does the total (= synchrotron plus Compton) emission.« less

Chasing passive galaxies in the early Universe: a critical analysis in CANDELS GOODS-South

NASA Astrophysics Data System (ADS)

Merlin, E.; Fontana, A.; Castellano, M.; Santini, P.; Torelli, M.; Boutsia, K.; Wang, T.; Grazian, A.; Pentericci, L.; Schreiber, C.; Ciesla, L.; McLure, R.; Derriere, S.; Dunlop, J. S.; Elbaz, D.

2018-01-01

We search for passive galaxies at z > 3 in the GOODS-South field, using different techniques based on photometric data, and paying attention to develop methods that are sensitive to objects that have become passive shortly before the epoch of observation. We use CANDELS HST catalogues, ultra-deep Ks data and new IRAC photometry, performing spectral energy distribution fitting using models with abruptly quenched star formation histories. We then single out galaxies which are best fitted by a passively evolving model, and having only low probability (<5 per cent) star-forming solutions. We verify the effects of including nebular lines emission, and we consider possible solutions at different redshifts. The number of selected sources dramatically depends on the models used in the spectral energy distribution (SED) fitting. Without including emission lines and with photometric redshifts fixed at the CANDELS estimate, we single out 30 candidates; the inclusion of nebular lines emission reduces the sample to 10 objects; allowing for solutions at different redshifts, only two galaxies survive as robust candidates. Most of the candidates are not far-infrared emitters, corroborating their association with passive galaxies. Our results translate into an upper limit in the number density of ∼0.173 arcmin2 above the detection limit. However, we conclude that the selection of passive galaxies at z > 3 is still subject to significant uncertainties, being sensitive to assumptions in the SED modelling adopted and to the relatively low S/N of the objects. By means of dedicated simulations, we show that JWST will greatly enhance the accuracy, allowing for a much more robust classification.
Do safety engineered devices reduce needle-stick injuries?

PubMed

Schuurmans, J; Lutgens, S P; Groen, L; Schneeberger, P M

2018-05-05

Needle stick injuries (NSIs) are one of the most common health hazards facing health care workers (HCWs) across the globe. Needles with safety engineered devices (SEDs) have been developed to minimize the risk of exposure to blood-borne infections such as Hepatitis B virus (HBV), Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) associated with NSIs. To assess the effect of the introduction of SEDs in preventing NSIs among HCWs in the Jeroen Bosch Hospital (JBH), the Netherlands. We compared the incidence of reported NSIs before and after the introduction of SEDs. All HCWs who reported a NSI with a SED were interviewed in order to understand the underlying causes of the NSIs. Despite the introduction of SEDs the incidence of NSIs increased from 1.9/100 HCWs before the introduction of SEDs to 2.2/100 HCWs after the introduction of SEDs. The registration of reported SED related NSIs showed a significant decrease in the number of NSIs related to injection needles and blood sugar needles, while an unexpected significant increase in NSIs with nadroparin calcium needles and infusion needles was found. The most common causes reported for NSIs were unsafe disposal of the needles and problems with the safety feature. The application of SEDs has not led to a reduction of NSIs. The majority of NSIs caused by a needle with a SED can be prevented by stimulation of safe needle disposal, proper use of SEDs and provision of feedback to manufacturers to keep improving product design. Copyright © 2018. Published by Elsevier Ltd.
Role of the putative structural protein Sed1p in mitochondrial genome maintenance.

PubMed

Phadnis, Naina; Ayres Sia, Elaine

2004-09-24

The nuclear gene MIP1 encodes the mitochondrial DNA polymerase responsible for replicating the mitochondrial genome in Saccharomyces cerevisiae. A number of other factors involved in replicating and segregating the mitochondrial genome are yet to be identified. Here, we report that a bacterial two-hybrid screen using the mitochondrial polymerase, Mip1p, as bait identified the yeast protein Sed1p. Sed1p is a cell surface protein highly expressed in the stationary phase. We find that several modified forms of Sed1p are expressed and the largest of these forms interacts with the mitochondrial polymerase in vitro. Deletion of SED1 causes a 3.5-fold increase in the rate of mitochondrial DNA point mutations as well as a 4.3-fold increase in the rate of loss of respiration. In contrast, we see no change in the rate of nuclear point mutations indicating the specific role of Sed1p function in mitochondrial genome stability. Indirect immunofluorescence analysis of Sed1p localization shows that Sed1p is targeted to the mitochondria. Moreover, Sed1p is detected in purified mitochondrial fractions and the localization to the mitochondria of the largest modified form is insensitive to the action of proteinase K. Deletion of the sed1 gene results in a reduction in the quantity of Mip1p and also affects the levels of a mitochondrially-expressed protein, Cox3p. Our results point towards a role for Sed1p in mitochondrial genome maintenance.
EMITTING ELECTRONS AND SOURCE ACTIVITY IN MARKARIAN 501

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mankuzhiyil, Nijil; Ansoldi, Stefano; Persic, Massimo

2012-07-10

We study the variation of the broadband spectral energy distribution (SED) of the BL Lac object Mrk 501 as a function of source activity, from quiescent to flaring. Through {chi}{sup 2}-minimization we model eight simultaneous SED data sets with a one-zone synchrotron self-Compton (SSC) model, and examine how model parameters vary with source activity. The emerging variability pattern of Mrk 501 is complex, with the Compton component arising from {gamma}-e scatterings that sometimes are (mostly) Thomson and sometimes (mostly) extreme Klein-Nishina. This can be seen from the variation of the Compton to synchrotron peak distance according to source state. Themore » underlying electron spectra are faint/soft in quiescent states and bright/hard in flaring states. A comparison with Mrk 421 suggests that the typical values of the SSC parameters are different in the two sources: however, in both jets the energy density is particle-dominated in all states.« less
Summertime conditions of a muddy estuarine environment: the EsCoSed project contribution.

PubMed

Brocchini, Maurizio; Calantoni, Joseph; Reed, Allen H; Postacchini, Matteo; Lorenzoni, Carlo; Russo, Aniello; Mancinelli, Alessandro; Corvaro, Sara; Moriconi, Giacomo; Soldini, Luciano

2015-01-01

As part of the Estuarine Cohesive Sediments (EsCoSed) project, a field experiment was performed in a highly engineered environment, acting as a natural laboratory, to study the physico-chemical properties of estuarine sediments and the associated hydro-morphodynamics during different seasons. The present contribution focuses on the results obtained from the summertime monitoring of the most downstream part of the Misa River (Senigallia, Italy). The measured hydrodynamics suggested a strong interaction between river current, wave forcing and tidal motion; flow velocities, affected by wind waves traveling upstream, changed significantly along the water column in both direction and magnitude. Surficial salinities in the estuary were low in the upper reaches of the estuary and exceeded 10 psu before the river mouth. Montmorillonite dominated the clay mineral assemblage, suggesting that large, low density flocs with high settling velocities (>1 mm s(-1)) may dominate the suspended aggregate materials.
Dust Abundance Variations in the Magellanic Clouds: Probing the Life-cycle of Metals with All-sky Surveys

NASA Astrophysics Data System (ADS)

Roman-Duval, Julia; Bot, Caroline; Chastenet, Jeremy; Gordon, Karl

2017-06-01

Observations and modeling suggest that dust abundance (gas-to-dust ratio, G/D) depends on (surface) density. Variations of the G/D provide timescale constraints for the different processes involved in the life cycle of metals in galaxies. Recent G/D measurements based on Herschel data suggest a factor of 5-10 decrease in dust abundance between the dense and diffuse interstellar media (ISM) in the Magellanic Clouds. However, the relative nature of the Herschel measurements precludes definitive conclusions as to the magnitude of those variations. We investigate variations of the dust abundance in the LMC and SMC using all-sky far-infrared surveys, which do not suffer from the limitations of Herschel on their zero-point calibration. We stack the dust spectral energy distribution (SED) at 100, 350, 550, and 850 microns from IRAS and Planck in intervals of gas surface density, model the stacked SEDs to derive the dust surface density, and constrain the relation between G/D and gas surface density in the range 10-100 M ⊙ pc-2 on ˜80 pc scales. We find that G/D decreases by factors of 3 (from 1500 to 500) in the LMC and 7 (from 1.5× {10}4 to 2000) in the SMC between the diffuse and dense ISM. The surface-density-dependence of G/D is consistent with elemental depletions, and with simple modeling of the accretion of gas-phase metals onto dust grains. This result has important implications for the sub-grid modeling of galaxy evolution, and for the calibration of dust-based gas-mass estimates, both locally and at high redshift.
The design and implementation of the Dynamic Ionosphere Cubesat Experiment (DICE) science instruments

NASA Astrophysics Data System (ADS)

Burr, Steven Reed

Dynamic Ionosphere Cubesat Experiment (DICE) is a satellite project funded by the National Science Foundation (NSF) to study the ionosphere, more particularly Storm Enhanced Densities (SED) with a payload consisting of plasma diagnostic instrumentation. Three instruments onboard DICE include an Electric Field Probe (EFP), Ion Langmuir Probe (ILP), and Three Axis Magnetometer (TAM). The EFP measures electric fields from +/-8V and consists of three channels a DC to 40Hz channel, a Floating Potential Probe (FPP), and an spectrographic channel with four bands from 16Hz to 512Hz. The ILP measures plasma densities from 1x104 cm--3 to 2x107 cm--3. The TAM measures magnetic field strength with a range +/-0.5 Gauss with a sensitivity of 2nT. To achieve desired mission requirements careful selection of instrument requirements and planning of the instrumentation design to achieve mission success. The analog design of each instrument is described in addition to the digital framework required to sample the science data at a 70Hz rate and prepare the data for the Command and Data Handing (C&DH) system. Calibration results are also presented and show fulfillment of the mission and instrumentation requirements.
15 CFR 752.15 - Export clearance.

Code of Federal Regulations, 2012 CFR

2012-01-01

... System (AES) record. The SED or AES record covering an export made under an SCL must be prepared in... EAR. (1) Item descriptions. Item descriptions on the SED or AES record must indicate specifically the... each shipment on the respective SED or AES record. (3) SCL number. The SED or AES record must include...
Preparation and characterisation of hydrocortisone particles using a supercritical fluids extraction process.

PubMed

Velaga, Sitaram P; Ghaderi, Raouf; Carlfors, Johan

2002-01-14

Crystallisation and subsequent milling of pharmaceutical powders by traditional methods often cause variations in physicochemical properties thereby influencing bioavailability of the formulation. Crystallisation of drug substances using supercritical fluids (SFs) offers some advantages over existing traditional methods in controlling particle characteristics. The novel particle formation method, solution enhanced dispersion by supercritical (SEDS) fluids was used for the preparation of hydrocortisone (HC) particles. The influence of processing conditions on the solid-state properties of the particles was studied. HC, an anti-inflammatory corticosteroid, particles were prepared from acetone and methanol solutions using the SEDS process. The solutions were dispersed with supercritical CO(2), acting as an anti-solvent, through a specially designed co-axial nozzle into a pressured vessel maintained at a specific constant temperature and pressure. The temperatures and pressures studied were 40-90 degrees C and 90-180 bar, respectively. The relative flow rates of drug solution to CO(2) were varied between 0.002 and 0.03. Solid-state characterisation of particles included differential scanning calorimetry (DSC), X-ray powder diffraction (XRPD), solubility studies and scanning electron microscopy (SEM) examination. The aerodynamic properties of SEDS prepared particles were determined by a multistage liquid impinger (MLI). Particles produced from acetone solutions were crystalline needles, melting at 221+/-2 degrees C. Their morphology was independent of processing conditions. With methanol solutions, particles were flakes or needles depending on the processing temperature and pressure. This material melted at 216+/-1 degrees C, indicating a different crystal structure from the original material, in agreement with observed differences in the position and intensity of the XRPD peaks. The simulated lung deposition, using the MLI, for HC powder was improved after SEDS processing. It was possible to produce and control the crystallinity, morphology, and aerodynamic properties of HC particles with the SEDS technique. This method may be useful for the processing of inhalation powders.
Supercritical fluids crystallization of budesonide and flunisolide.

PubMed

Velaga, Sitaram P; Berger, Rolf; Carlfors, Johan

2002-10-01

Budesonide and flunisolide anhydrate were crystallized using the solution enhanced dispersion by supercritical fluids (SEDS) technique. The aim was to investigate the possibility of preparing different pure polymorphs. 0.25% w/v solutions of each drug were prepared from acetone and methanol. Operating conditions were 40-80 degrees C and 80-200 bars. The flow rate of drug solution was 0.3 mL/min and that of CO2 was 9-25 mL/min. Sample characterizations included differential scanning calorimetry, X-ray powder diffraction, variable temperature X-ray diffraction, scanning electron microscopy, and solubility studies. The particle morphology of budesonide was dependent on the nature of the solvent. SEDS processing of flunisolide with acetone at 100 bars resulted in the formation of polymorphic mixtures at 80 degrees C and a new polymorph III at 60 C and 40 degrees C. With methanol at 100 bars another new polymorph IV was formed with different particle morphology at 80 degrees C and a polymorphic mixture at 60 degrees C. Using the SEDS, microparticles of crystalline budesonide were prepared and new polymorphs of flunisolide were produced. Particle characteristics were controlled by the temperature, pressure and relative flow rates of drug solution and CO2.
BayeSED: A General Approach to Fitting the Spectral Energy Distribution of Galaxies

NASA Astrophysics Data System (ADS)

Han, Yunkun; Han, Zhanwen

2014-11-01

We present a newly developed version of BayeSED, a general Bayesian approach to the spectral energy distribution (SED) fitting of galaxies. The new BayeSED code has been systematically tested on a mock sample of galaxies. The comparison between the estimated and input values of the parameters shows that BayeSED can recover the physical parameters of galaxies reasonably well. We then applied BayeSED to interpret the SEDs of a large Ks -selected sample of galaxies in the COSMOS/UltraVISTA field with stellar population synthesis models. Using the new BayeSED code, a Bayesian model comparison of stellar population synthesis models has been performed for the first time. We found that the 2003 model by Bruzual & Charlot, statistically speaking, has greater Bayesian evidence than the 2005 model by Maraston for the Ks -selected sample. In addition, while setting the stellar metallicity as a free parameter obviously increases the Bayesian evidence of both models, varying the initial mass function has a notable effect only on the Maraston model. Meanwhile, the physical parameters estimated with BayeSED are found to be generally consistent with those obtained using the popular grid-based FAST code, while the former parameters exhibit more natural distributions. Based on the estimated physical parameters of the galaxies in the sample, we qualitatively classified the galaxies in the sample into five populations that may represent galaxies at different evolution stages or in different environments. We conclude that BayeSED could be a reliable and powerful tool for investigating the formation and evolution of galaxies from the rich multi-wavelength observations currently available. A binary version of the BayeSED code parallelized with Message Passing Interface is publicly available at https://bitbucket.org/hanyk/bayesed.
BayeSED: A GENERAL APPROACH TO FITTING THE SPECTRAL ENERGY DISTRIBUTION OF GALAXIES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Han, Yunkun; Han, Zhanwen, E-mail: hanyk@ynao.ac.cn, E-mail: zhanwenhan@ynao.ac.cn

2014-11-01

We present a newly developed version of BayeSED, a general Bayesian approach to the spectral energy distribution (SED) fitting of galaxies. The new BayeSED code has been systematically tested on a mock sample of galaxies. The comparison between the estimated and input values of the parameters shows that BayeSED can recover the physical parameters of galaxies reasonably well. We then applied BayeSED to interpret the SEDs of a large K{sub s} -selected sample of galaxies in the COSMOS/UltraVISTA field with stellar population synthesis models. Using the new BayeSED code, a Bayesian model comparison of stellar population synthesis models has beenmore » performed for the first time. We found that the 2003 model by Bruzual and Charlot, statistically speaking, has greater Bayesian evidence than the 2005 model by Maraston for the K{sub s} -selected sample. In addition, while setting the stellar metallicity as a free parameter obviously increases the Bayesian evidence of both models, varying the initial mass function has a notable effect only on the Maraston model. Meanwhile, the physical parameters estimated with BayeSED are found to be generally consistent with those obtained using the popular grid-based FAST code, while the former parameters exhibit more natural distributions. Based on the estimated physical parameters of the galaxies in the sample, we qualitatively classified the galaxies in the sample into five populations that may represent galaxies at different evolution stages or in different environments. We conclude that BayeSED could be a reliable and powerful tool for investigating the formation and evolution of galaxies from the rich multi-wavelength observations currently available. A binary version of the BayeSED code parallelized with Message Passing Interface is publicly available at https://bitbucket.org/hanyk/bayesed.« less
Socioeconomic Disadvantage Moderates the Association between Peripheral Biomarkers and Childhood Psychopathology

PubMed Central

Mansur, Rodrigo B.; Cunha, Graccielle R.; Asevedo, Elson; Zugman, André; Zeni-Graiff, Maiara; Rios, Adiel C.; Sethi, Sumit; Maurya, Pawan K.; Levandowski, Mateus L.; Gadelha, Ary; Pan, Pedro M.; Stertz, Laura; Belangero, Síntia I.; Kauer-Sant' Anna, Márcia; Teixeira, Antônio L.; Mari, Jair J.; Rohde, Luis A.; Miguel, Euripedes C.; McIntyre, Roger S.; Grassi-Oliveira, Rodrigo; Bressan, Rodrigo A.; Brietzke, Elisa

2016-01-01

Background Socioeconomic disadvantage (SED) has been consistently associated with early life mental health problems. SED has been shown to impact multiple biological systems, including the regulation of neurotrophic proteins, immune-inflammatory and oxidative stress markers, which, conversely, have been reported to be relevant to physiological and pathological neurodevelopment This study investigated the relationship between SED, different domains of psychopathology, serum levels of interleukin-6 (IL6), thiobarbituric acid-reactive substance (TBARS) and brain-derived neurotrophic factor (BDNF). We hypothesized that a composite of socioeconomic risk would be associated with psychopathology and altered levels of peripheral biomarkers. In addition, we hypothesized that SED would moderate the associations between mental health problems, IL6, TBARS and BDNF. Methods and Findings Using a cross-sectional design, we measured the serum levels of IL6, TBARS and BDNF in 495 children aged 6 to 12. We also investigated socio-demographic characteristics and mental health problems using the Child Behaviour Checklist (CBCL) DSM-oriented scales. SED was evaluated using a cumulative risk model. Generalized linear models were used to assess associations between SED, biomarkers levels and psychopathology. SED was significantly associated with serum levels of IL6 (RR = 1.026, 95% CI 1.004; 1.049, p = 0.020) and TBARS (RR = 1.077, 95% CI 1.028; 1.127, p = 0.002). The association between SED and BDNF was not statistically significant (RR = 1.031, 95% CI 0.997; 1.066, p = 0.077). SED was also significantly associated with all CBCL DSM-oriented scales (all p < 0.05), whereas serum biomarkers (i.e. IL6, TBARS, BDNF) were associated with specific subscales. Moreover, the associations between serum biomarkers and domains of psychopathology were moderated by SED, with stronger correlations between mental health problems, IL6, TBARS, and BDNF being observed in children with high SED. Conclusions In children, SED is highly associated with mental health problems. Our findings suggest that this association may be moderated via effects on multiple interacting neurobiological systems. PMID:27489945
Sparse targets in hydroacoustic surveys: Balancing quantity and quality of in situ target strength data

USGS Publications Warehouse

DuFour, Mark R.; Mayer, Christine M.; Kocovsky, Patrick; Qian, Song; Warner, David M.; Kraus, Richard T.; Vandergoot, Christopher

2017-01-01

Hydroacoustic sampling of low-density fish in shallow water can lead to low sample sizes of naturally variable target strength (TS) estimates, resulting in both sparse and variable data. Increasing maximum beam compensation (BC) beyond conventional values (i.e., 3 dB beam width) can recover more targets during data analysis; however, data quality decreases near the acoustic beam edges. We identified the optimal balance between data quantity and quality with increasing BC using a standard sphere calibration, and we quantified the effect of BC on fish track variability, size structure, and density estimates of Lake Erie walleye (Sander vitreus). Standard sphere mean TS estimates were consistent with theoretical values (−39.6 dB) up to 18-dB BC, while estimates decreased at greater BC values. Natural sources (i.e., residual and mean TS) dominated total fish track variation, while contributions from measurement related error (i.e., number of single echo detections (SEDs) and BC) were proportionally low. Increasing BC led to more fish encounters and SEDs per fish, while stability in size structure and density were observed at intermediate values (e.g., 18 dB). Detection of medium to large fish (i.e., age-2+ walleye) benefited most from increasing BC, as proportional changes in size structure and density were greatest in these size categories. Therefore, when TS data are sparse and variable, increasing BC to an optimal value (here 18 dB) will maximize the TS data quantity while limiting lower-quality data near the beam edges.
Combined Effects of Rosuvastatin and Exercise on Gene Expression of Key Molecules Involved in Cholesterol Metabolism in Ovariectomized Rats

PubMed Central

Ngo Sock, Emilienne Tudor; Mayer, Gaétan; Lavoie, Jean-Marc

2016-01-01

The purpose of this study was to investigate the effects of three weeks of rosuvastatin (Ros) treatment alone and in combination with voluntary training (Tr) on expression of genes involved in cholesterol metabolism (LDLR, PCSK9, LRP-1, SREBP-2, IDOL, ACAT-2 and HMGCR) in the liver of eight week-old ovariectomized (Ovx) rats. Sprague Dawley rats were Ovx or sham-operated (Sham) and kept sedentary for 8 weeks under a standard diet. Thereafter, rats were transferred for three weeks in running wheel cages for Tr or kept sedentary (Sed) with or without Ros treatment (5mg/kg/day). Six groups were formed: Sham-Sed treated with saline (Sal) or Ros (Sham-Sed-Sal; Sham-Sed-Ros), Ovx-Sed treated with Sal or Ros (Ovx-Sed-Sal; Ovx-Sed-Ros), Ovx trained treated with Sal or Ros (Ovx-Tr-Sal; Ovx-Tr-Ros). Ovx-Sed-Sal rats depicted higher (P < 0.05) body weight, plasma total cholesterol (TC) and LDL-C, and liver TC content compared to Sham-Sed-Sal rats. In contrast, mRNA levels of liver PCSK9, LDLR, LRP-1 as well as plasma PCSK9 concentrations and protein levels of LRP-1 were reduced (P < 0.01) in Ovx-Sed-Sal compared to Sham-Sed-Sal rats. However, protein levels of LDLR increased (P < 0.05) in Ovx-Sed-Sal compared to Sham-Sed-Sal rats. Treatment of Ovx rats with Ros increased (P < 0.05) mRNA and protein levels of LRP-1 and PCSK9 but not mRNA levels of LDLR, while its protein abundance was reduced at the level of Sham rats. As a result, plasma LDL-C was not reduced. Exercise alone did not affect the expression of any of these markers in Ovx rats. Overall, Ros treatment corrected Ovx-induced decrease in gene expression of markers of cholesterol metabolism in liver of Ovx rats, but without reducing plasma LDL-C concentrations. Increased plasma PCSK9 levels could be responsible for the reduction of liver LDLR protein abundance and the absence of reduction of plasma LDL-C after Ros treatment. PMID:27442011
SEDS1 mission software verification using a signal simulator

NASA Technical Reports Server (NTRS)

Pierson, William E.

1992-01-01

The first flight of the Small Expendable Deployer System (SEDS1) is schedule to fly as the secondary payload of a Delta 2 in March, 1993. The objective of the SEDS1 mission is to collect data to validate the concept of tethered satellite systems and to verify computer simulations used to predict their behavior. SEDS1 will deploy a 50 lb. instrumented satellite as an end mass using a 20 km tether. Langley Research Center is providing the end mass instrumentation, while the Marshall Space Flight Center is designing and building the deployer. The objective of the experiment is to test the SEDS design concept by demonstrating that the system will satisfactorily deploy the full 20 km tether without stopping prematurely, come to a smooth stop on the application of a brake, and cut the tether at the proper time after it swings to the local vertical. Also, SEDS1 will collect data which will be used to test the accuracy of tether dynamics models used to stimulate this type of deployment. The experiment will last about 1.5 hours and complete approximately 1.5 orbits. Radar tracking of the Delta II and end mass is planned. In addition, the SEDS1 on-board computer will continuously record, store, and transmit mission data over the Delta II S-band telemetry system. The Data System will count tether windings as the tether unwinds, log the times of each turn and other mission events, monitor tether tension, and record the temperature of system components. A summary of the measurements taken during the SEDS1 are shown. The Data System will also control the tether brake and cutter mechanisms. Preliminary versions of two major sections of the flight software, the data telemetry modules and the data collection modules, were developed and tested under the 1990 NASA/ASEE Summer Faculty Fellowship Program. To facilitate the debugging of these software modules, a prototype SEDS Data System was programmed to simulate turn count signals. During the 1991 summer program, the concept of simulating signals produced by the SEDS electronics systems and circuits was expanded and more precisely defined. During the 1992 summer program, the SEDS signal simulator was programmed to test the requirements of the SEDS Mission software, and this simulator will be used in the formal verification of the SEDS Mission Software. The formal test procedures specification was written which incorporates the use of the signal simulator to test the SEDS Mission Software and which incorporates procedures for testing the other major component of the SEDS software, the Monitor Software.
X-ray detections of submillimetre galaxies: active galactic nuclei versus starburst contribution

NASA Astrophysics Data System (ADS)

Johnson, S. P.; Wilson, G. W.; Wang, Q. D.; Williams, C. C.; Scott, K. S.; Yun, M. S.; Pope, A.; Lowenthal, J.; Aretxaga, I.; Hughes, D.; Kim, M. J.; Kim, S.; Tamura, Y.; Kohno, K.; Ezawa, H.; Kawabe, R.; Oshima, T.

2013-05-01

We present a large-scale study of the X-ray properties and near-IR-to-radio spectral energy distributions (SEDs) of submillimetre galaxies (SMGs) detected at 1.1 mm with the AzTEC instrument across a ˜1.2 square degree area of the sky. Combining deep 2-4 Ms Chandra data with Spitzer IRAC/MIPS and Very Large Array data within the Great Observatories Origins Deep Survey North (GOODS-N), GOODS-S and COSMOS fields, we find evidence for active galactic nucleus (AGN) activity in ˜14 per cent of 271 AzTEC SMGs, ˜28 per cent considering only the two GOODS fields. Through X-ray spectral modelling and multiwavelength SED fitting using Monte Carlo Markov chain techniques to Siebenmorgen et al. (AGN) and Efstathiou, Rowan-Robinson & Siebenmorgen (starburst) templates, we find that while star formation dominates the IR emission, with star formation rates (SFRs) ˜100-1000 M⊙ yr-1, the X-ray emission for most sources is almost exclusively from obscured AGNs, with column densities in excess of 1023 cm-2. Only for ˜6 per cent of our sources do we find an X-ray-derived SFR consistent with NIR-to-radio SED derived SFRs. Inclusion of the X-ray luminosities as a prior to the NIR-to-radio SED effectively sets the AGN luminosity and SFR, preventing significant contribution from the AGN template. Our SED modelling further shows that the AGN and starburst templates typically lack the required 1.1 mm emission necessary to match observations, arguing for an extended, cool dust component. The cross-correlation function between the full samples of X-ray sources and SMGs in these fields does not indicate a strong correlation between the two populations at large scales, suggesting that SMGs and AGNs do not necessarily trace the same underlying large-scale structure. Combined with the remaining X-ray-dim SMGs, this suggests that sub-mm-bright sources may evolve along multiple tracks, with X-ray-detected SMGs representing transitionary objects between periods of high star formation and AGN activity, while X-ray-faint SMGs represent a brief starburst phase of more normal galaxies.
Langmuir Probe Spacecraft Potential End Item Specification Document

NASA Technical Reports Server (NTRS)

Gilchrist, Brian; Curtis, Leslie (Technical Monitor)

2001-01-01

This document describes the Langmuir Probe Spacecraft Potential (LPSP) investigation of the plasma environment in the vicinity of the ProSEDS Delta II spacecraft. This investigation will employ a group of three (3) Langmuir Probe Assemblies, LPAs, mounted on the Delta II second stage to measure the electron density and temperature (n(sub e) and T(sub e)), the ion density (n(sub i)), and the spacecraft potential (V(sub s)) relative to the surrounding ionospheric plasma. This document is also intended to define the technical requirements and flight-vehicle installation interfaces for the design, development, assembly, testing, qualification, and operation of the LPSP subsystem for the Propulsive Small Expendable Deployer System (ProSEDS) and its associated Ground Support Equipment (GSE). This document also defines the interfaces between the LPSP instrument and the ProSEDS Delta II spacecraft, as well as the design, fabrication, operation, and other requirements established to meet the mission objectives. The LPSP is the primary measurement instrument designed to characterize the background plasma environment and is a supporting instrument for measuring spacecraft potential of the Delta II vehicle used for the ProSEDS mission. Specifically, the LPSP will use the three LPAs equally spaced around the Delta II body to make measurements of the ambient ionospheric plasma during passive operations to aid in validating existing models of electrodynamic-tether propulsion. These same probes will also be used to measure Delta II spacecraft potential when active operations occur. When the electron emitting plasma contractor is on, dense neutral plasma is emitted. Effective operation of the plasma contactor (PC) will mean a low potential difference between the Delta II second stage and the surrounding plasma and represents one of the voltage parameters needed to fully characterize the electrodynamic-tether closed circuit. Given that the LP already needs to be well away from any near-field disturbances around the Delta II, it is possible to use the same probe with a simple reconfiguration of the electronics to measure potential with respect to the ambient plasma. The LP measurement techniques are outlined in the following text and discussed in detail in the Appendix. The scientific goals of the investigation, the physical and electrical characteristics of the instrument, and the on-orbit measurement requirements are also discussed in this document.
Serious emotional disturbance among youths exposed to Hurricane Katrina 2 years postdisaster.

PubMed

McLaughlin, Katie A; Fairbank, John A; Gruber, Michael J; Jones, Russell T; Lakoma, Matthew D; Pfefferbaum, Betty; Sampson, Nancy A; Kessler, Ronald C

2009-11-01

To estimate the prevalence of serious emotional disturbance (SED) among children and adolescents exposed to Hurricane Katrina along with the associations of SED with hurricane-related stressors, sociodemographics, and family factors 18 to 27 months after the hurricane. A probability sample of prehurricane residents of areas affected by Hurricane Katrina was administered a telephone survey. Respondents provided information on up to two of their children (n = 797) aged 4 to 17 years. The survey assessed hurricane-related stressors and lifetime history of psychopathology in respondents, screened for 12-month SED in respondents' children using the Strengths and Difficulties Questionnaire, and determined whether children's emotional and behavioral problems were attributable to Hurricane Katrina. The estimated prevalence of SED was 14.9%, and 9.3% of the youths were estimated to have SED that is directly attributable to Hurricane Katrina. Stress exposure was associated strongly with SED, and 20.3% of the youths with high stress exposure had hurricane-attributable SED. Death of a loved one had the strongest association with SED among prehurricane residents of New Orleans, whereas exposure to physical adversity had the strongest association in the remainder of the sample. Among children with stress exposure, parental psychopathology and poverty were associated with SED. The prevalence of SED among youths exposed to Hurricane Katrina remains high 18 to 27 months after the storm, suggesting a substantial need for mental health treatment resources in the hurricane-affected areas. The youths who were exposed to hurricane-related stressors, have a family history of psychopathology, and have lower family incomes are at greatest risk for long-term psychiatric impairment.
Solar energy demand (SED) of commodity life cycles.

PubMed

Rugani, Benedetto; Huijbregts, Mark A J; Mutel, Christopher; Bastianoni, Simone; Hellweg, Stefanie

2011-06-15

The solar energy demand (SED) of the extraction of 232 atmospheric, biotic, fossil, land, metal, mineral, nuclear, and water resources was quantified and compared with other energy- and exergy-based indicators. SED represents the direct and indirect solar energy required by a product or service during its life cycle. SED scores were calculated for 3865 processes, as implemented in the Ecoinvent database, version 2.1. The results showed that nonrenewable resources, and in particular minerals, formed the dominant contribution to SED. This large share is due to the indirect solar energy required to produce these resource inputs. Compared with other energy- and exergy-based indicators, SED assigns higher impact factors to minerals and metals and smaller impact factors to fossil energetic resources, land use, and nuclear energy. The highest differences were observed for biobased and renewable energy generation processes, whose relative contribution of renewable resources such as water, biomass, and land occupation was much lower in SED than in energy- and exergy-based indicators.

Improving rheology and enzymatic hydrolysis of high-solid corncob slurries by adding lignosulfonate and long-chain fatty alcohols.

PubMed

Lou, Hongming; Wu, Shun; Li, Xiuli; Lan, Tianqing; Yang, Dongjie; Pang, Yuxia; Qiu, Xueqing; Li, Xuehui; Huang, Jinhao

2014-08-20

The effects of lignosulfonate (SXSL) and long-chain fatty alcohols (LFAs) on the rheology and enzymatic hydrolysis of high-solid corncob slurries were investigated. The application of 2.5% (w/w) SXSL increased the substrate enzymatic digestibility (SED) of high-solid corncob slurries at 72 h from 31.7 to 54.0%, but meanwhile it increased the slurry's yield stress and complex viscosity to make the slurry difficult to stir and pump. The smallest molecular weight (MW) SXSL fraction had the strongest enhancement on SED. The SXSL fraction with large MW had a negative effect on rheology. n-Octanol (C8) and n-decanol (C10) improved the rheological properties of high-solid slurry and are strong enough to counteract the negative effect of SXSL. Furthermore, C8 and C10 clearly enhanced the enzymatic hydrolysis of high-solid corncob slurries with and without SXSL. A mechanism was proposed to explain the observed negative effect of SXSL and the positive effect of LFAs on the rheological properties.
Radial Surface Density Profiles of Gas and Dust in the Debris Disk Around 49 Ceti

NASA Technical Reports Server (NTRS)

Hughes, A. Meredith; Lieman-Sifry, Jesse; Flaherty, Kevin M.; Daley, Cail M.; Roberge, Aki; Kospal, Agnes; Moor, Attila; Kamp, Inga; Wilner, David J.; Andrews, Sean M.;

2017-01-01

We present approximately 0".4 resolution images of CO(3-2) and associated continuum emission from the gas-bearing debris disk around the nearby A star 49 Ceti, observed with the Atacama Large Millimeter/Submillimeter Array (ALMA). We analyze the ALMA visibilities in tandem with the broadband spectral energy distribution to measure the radial surface density profiles of dust and gas emission from the system. The dust surface density decreases with radius between approximately 100 and 310 au, with a marginally significant enhancement of surface density at a radius of approximately 110 au. The SED requires an inner disk of small grains in addition to the outer disk of larger grains resolved by ALMA. The gas disk exhibits a surface density profile that increases with radius, contrary to most previous spatially resolved observations of circumstellar gas disks. While approximately 80% of the CO flux is well described by an axisymmetric power-law disk in Keplerian rotation about the central star, residuals at approximately 20% of the peak flux exhibit a departure from axisymmetry suggestive of spiral arms or a warp in the gas disk. The radial extent of the gas disk (approx. 220 au) is smaller than that of the dust disk (approx. 300 au), consistent with recent observations of other gasbearing debris disks. While there are so far only three broad debris disks with well characterized radial dust profiles at millimeter wavelengths, 49 Ceti's disk shows a markedly different structure from two radially resolved gas-poor debris disks, implying that the physical processes generating and sculpting the gas and dust are fundamentally different.

Correlates of objectively measured sedentary time and self-reported screen time in Canadian children.

PubMed

LeBlanc, Allana G; Broyles, Stephanie T; Chaput, Jean-Philippe; Leduc, Geneviève; Boyer, Charles; Borghese, Michael M; Tremblay, Mark S

2015-03-18

Demographic, family, and home characteristics play an important role in determining childhood sedentary behaviour. The objective of this paper was to identify correlates of total sedentary time (SED) and correlates of self-reported screen time (ST) in Canadian children. Child- and parent-reported household, socio-demographic, behavioural, and diet related data were collected; directly measured anthropometric and accelerometer data were also collected for each child. Participants with complete demographic, anthropometric, and either SED (n=524, 41% boys) or ST (n=567, 42% boys) data from the Canadian site of the International Study of Childhood Obesity Lifestyle and the Environment (ISCOLE) were included in analysis. Sixteen potential correlates of SED and ST were examined using multilevel general linear models, adjusting for sex, ethnicity, number of siblings, and socio-economic status. All explanatory variables moderately associated (p<0.10) with SED and/or ST in univariate analyses were included in the final, fully-adjusted models. Variables that remained significant in the final models (p<0.05) were considered correlates of SED and/or ST. Children averaged 8.5 hours of daily SED; no differences in total SED, or total ST were seen between girls and boys, but boys reported significantly more video game/computer usage than girls. Boys also had higher waist circumference and BMI z-scores than girls. In the final models, waist circumference and number of TVs in the home were the only common correlates of both SED and ST. SED was also negatively associated with sleep duration. ST was also positively associated with mother's weight status, father's education, and unhealthy eating pattern score and negatively associated with healthy eating pattern score, and weekend breakfast consumption. Few common correlates existed between boys and girls. Several factors were identified as correlates of SED and/or of ST in Canadian children; however, few correlates were common for both SED and ST, and for both boys and girls. This suggests that a single strategy to reduce SED and ST is unlikely to be effective. Future work should examine a variety of other, non-screen based sedentary behaviours and their potential correlates in the hopes of creating tailored public health messages to reduce SED and ST in both boys, and girls.
Rupture Predictions of Notched Ti-6Al-4V Using Local Approaches

PubMed Central

Peron, Mirco; Berto, Filippo

2018-01-01

Ti-6Al-4V has been extensively used in structural applications in various engineering fields, from naval to automotive and from aerospace to biomedical. Structural applications are characterized by geometrical discontinuities such as notches, which are widely known to harmfully affect their tensile strength. In recent years, many attempts have been done to define solid criteria with which to reliably predict the tensile strength of materials. Among these criteria, two local approaches are worth mentioning due to the accuracy of their predictions, i.e., the strain energy density (SED) approach and the theory of critical distance (TCD) method. In this manuscript, the robustness of these two methods in predicting the tensile behavior of notched Ti-6Al-4V specimens has been compared. To this aim, two very dissimilar notch geometries have been tested, i.e., semi-circular and blunt V-notch with a notch root radius equal to 1 mm, and the experimental results have been compared with those predicted by the two models. The experimental values have been estimated with low discrepancies by either the SED approach and the TCD method, but the former results in better predictions. The deviations for the SED are in fact lower than 1.3%, while the TCD provides predictions with errors almost up to 8.5%. Finally, the weaknesses and the strengths of the two models have been reported. PMID:29693565
New NED XML/VOtable Services and Client Interface Applications

NASA Astrophysics Data System (ADS)

Pevunova, O.; Good, J.; Mazzarella, J.; Berriman, G. B.; Madore, B.

2005-12-01

The NASA/IPAC Extragalactic Database (NED) provides data and cross-identifications for over 7 million extragalactic objects fused from thousands of survey catalogs and journal articles. The data cover all frequencies from radio through gamma rays and include positions, redshifts, photometry and spectral energy distributions (SEDs), sizes, and images. NED services have traditionally supplied data in HTML format for connections from Web browsers, and a custom ASCII data structure for connections by remote computer programs written in the C programming language. We describe new services that provide responses from NED queries in XML documents compliant with the international virtual observatory VOtable protocol. The XML/VOtable services support cone searches, all-sky searches based on object attributes (survey names, cross-IDs, redshifts, flux densities), and requests for detailed object data. Initial services have been inserted into the NVO registry, and others will follow soon. The first client application is a Style Sheet specification for rendering NED VOtable query results in Web browsers that support XML. The second prototype application is a Java applet that allows users to compare multiple SEDs. The new XML/VOtable output mode will also simplify the integration of data from NED into visualization and analysis packages, software agents, and other virtual observatory applications. We show an example SED from NED plotted using VOPlot. The NED website is: http://nedwww.ipac.caltech.edu.
Serious Emotion Disturbance among Youth Exposed to Hurricane Katrina Two Years Post-Disaster

PubMed Central

McLaughlin, Katie A.; Fairbank, John A.; Gruber, Michael J.; Jones, Russell T.; Lakoma, Matthew D.; Pfefferbaum, Betty; Sampson, Nancy A.; Kessler, Ronald C.

2014-01-01

Objective To estimate the prevalence of serious emotional disturbance (SED) among children and adolescents exposed to Hurricane Katrina along with the associations of SED with hurricane-related stressors, socio-demographics, and family factors 18–27 months following the hurricane. Method A probability sample of pre-hurricane residents of areas affected by Hurricane Katrina was administered a telephone survey. Respondents provided information on up to two of their children (n=797) aged 4–17. The survey assessed hurricane-related stressors and lifetime history of psychopathology in respondents, screened for 12-month SED in respondents’ children using the Strengths and Difficulties Questionnaire (SDQ), and determined whether children’s emotional and behavioral problems were attributable to Hurricane Katrina. Results The estimated prevalence of SED was 14.9%, and 9.3% of youth were estimated to have SED that is directly attributable to Hurricane Katrina. Stress exposure was associated strongly with SED, and 20.3% of youth with high stress exposure had hurricane-attributable SED. Death of a loved one had the strongest association with SED among pre-hurricane residents of New Orleans, whereas exposure to physical adversity had the strongest association in the remainder of the sample. Among children with stress exposure, parental psychopathology and poverty were associated with SED. Conclusions The prevalence of SED among youth exposed to Hurricane Katrina remains high 18–27 months after the storm, suggesting a substantial need for mental health treatment resources in the hurricane-affected areas. Youth who were exposed to hurricane-related stressors, have a family history of psychopathology, and have lower family incomes are at greatest risk for long-term psychiatric impairment. PMID:19797983
Measurements of Solar Ultraviolet Radiation Exposure at Work and at Leisure in Danish Workers.

PubMed

Grandahl, Kasper; Eriksen, Paul; Ibler, Kristina Sophie; Bonde, Jens Peter; Mortensen, Ole Steen

2018-03-30

Exposure to solar ultraviolet radiation is the main cause of skin cancer and may well present an occupational health and safety problem. In Denmark, skin cancer is a common disease in the general population, but detailed data on solar ultraviolet radiation exposure among outdoor workers are lacking. The aim of this study was to provide objective measurements of solar ultraviolet radiation exposure on working days and at leisure and compare levels of exposure between groups of mainly outdoor, equal-parts-outdoor-and-indoor and indoor workers. To this end, UV-B dosimeters with an aluminum gallium nitride (AlGaN) photodiode detector were used to measure the solar ultraviolet radiation exposure of 457 workers in the Danish summer season. Presented as semi-annual standard erythemal dose (SED) on working days, respectively, at leisure, the results are for mainly outdoor workers 214.2 SED and 64.8 SED, equal-parts-outdoor-and-indoor workers 131.4 SED and 64.8 SED, indoor workers 55.8 SED and 57.6 SED. The daily SED by month is significantly different (α = 0.05) between mainly outdoor, equal-parts-outdoor-and-indoor and indoor workers and across professional groups; some of which are exposed at very high levels that is roofers 361.8 SED. These findings substantiate that exposure to solar ultraviolet radiation is indeed an occupational health and safety problem in Denmark. © 2018 The Authors. Photochemistry and Photobiology published by Wiley Periodicals, Inc. on behalf of American Society for Photobiology.
DIRT: Dust InfraRed Toolbox

NASA Astrophysics Data System (ADS)

Pound, Marc W.; Wolfire, Mark G.; Mundy, Lee G.; Teuben, Peter; Lord, Steve

2011-02-01

DIRT is a Java applet for modelling astrophysical processes in circumstellar dust shells around young and evolved stars. With DIRT, you can: select and display over 500,000 pre-run model spectral energy distributions (SEDs) find the best-fit model to your data set account for beam size in model fitting manipulate data and models with an interactive viewer display gas and dust density and temperature profiles display model intensity profiles at various wavelengths
Nebular and Stellar Dust Extinction Across the Disk of Emission-line Galaxies on Kiloparsec Scales

NASA Astrophysics Data System (ADS)

Hemmati, Shoubaneh; Mobasher, Bahram; Darvish, Behnam; Nayyeri, Hooshang; Sobral, David; Miller, Sarah

2015-11-01

We investigate the resolved kiloparsec-scale stellar and nebular dust distribution in eight star-forming galaxies at z ∼ 0.4 in the Great Observatories Origins Deep Survey fields. This is to get a better understanding of the effect of dust attenuation on measurements of physical properties and its variation with redshift. Constructing the observed spectral energy distributions (SEDs) per pixel, based on seven bands of photometric data from Hubble Space Telescope/Advanced Camera for Surveys and WFC3, we performed pixel-by-pixel SED fits to population synthesis models and estimated the small-scale distribution of stellar dust extinction. We use Hα/Hβ nebular emission line ratios from Keck/DEIMOS high-resolution spectra at each spatial resolution element to measure the amount of attenuation faced by ionized gas at different radii from the centers of galaxies. We find a good agreement between the integrated and median of resolved color excess measurements in our galaxies. The ratio of integrated nebular to stellar dust extinction is always greater than unity, but does not show any trend with stellar mass or star formation rate (SFR). We find that inclination plays an important role in the variation of the nebular to stellar excess ratio. The stellar color excess profiles are found to have higher values at the center compared to outer parts of the disk. However, for lower mass galaxies, a similar trend is not found for the nebular color excess. We find that the nebular color excess increases with stellar mass surface density. This explains the absence of radial trend in the nebular color excess in lower mass galaxies which lack a large radial variation of stellar mass surface density. Using standard conversions of SFR surface density to gas mass surface density, and the relation between dust mass surface density and color excess, we find no significant variation in the dust-to-gas ratio in regions with high gas mass surface densities over the scales probed in this study.
Lake sedimentary DNA accurately records 20th Century introductions of exotic conifers in Scotland.

PubMed

Sjögren, Per; Edwards, Mary E; Gielly, Ludovic; Langdon, Catherine T; Croudace, Ian W; Merkel, Marie Kristine Føreid; Fonville, Thierry; Alsos, Inger Greve

2017-01-01

Sedimentary DNA (sedDNA) has recently emerged as a new proxy for reconstructing past vegetation, but its taphonomy, source area and representation biases need better assessment. We investigated how sedDNA in recent sediments of two small Scottish lakes reflects a major vegetation change, using well-documented 20 th Century plantations of exotic conifers as an experimental system. We used next-generation sequencing to barcode sedDNA retrieved from subrecent lake sediments. For comparison, pollen was analysed from the same samples. The sedDNA record contains 73 taxa (mainly genus or species), all but one of which are present in the study area. Pollen and sedDNA shared 35% of taxa, which partly reflects a difference in source area. More aquatic taxa were recorded in sedDNA, whereas taxa assumed to be of regional rather than local origin were recorded only as pollen. The chronology of the sediments and planting records are well aligned, and sedDNA of exotic conifers appears in high quantities with the establishment of plantations around the lakes. SedDNA recorded other changes in local vegetation that accompanied afforestation. There were no signs of DNA leaching in the sediments or DNA originating from pollen. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.
Clinical laboratory urine analysis: comparison of the UriSed automated microscopic analyzer and the manual microscopy.

PubMed

Ma, Junlong; Wang, Chengbin; Yue, Jiaxin; Li, Mianyang; Zhang, Hongrui; Ma, Xiaojing; Li, Xincui; Xue, Dandan; Qing, Xiaoyan; Wang, Shengjiang; Xiang, Daijun; Cong, Yulong

2013-01-01

Several automated urine sediment analyzers have been introduced to clinical laboratories. Automated microscopic pattern recognition is a new technique for urine particle analysis. We evaluated the analytical and diagnostic performance of the UriSed automated microscopic analyzer and compared with manual microscopy for urine sediment analysis. Precision, linearity, carry-over, and method comparison were carried out. A total of 600 urine samples sent for urinalysis were assessed using the UriSed automated microscopic analyzer and manual microscopy. Within-run and between-run precision of the UriSed for red blood cells (RBC) and white blood cells (WBC) were acceptable at all levels (CV < 20%). Within-run and between-run imprecision of the UriSed testing for cast, squamous epithelial cells (EPI), and bacteria (BAC) were good at middle level and high level (CV < 20%). The linearity analysis revealed substantial agreement between the measured value and the theoretical value of the UriSed for RBC, WBC, cast, EPI, and BAC (r > 0.95). There was no carry-over. RBC, WBC, and squamous epithelial cells with sensitivities and specificities were more than 80% in this study. There is substantial agreement between the UriSed automated microscopic analyzer and the manual microscopy methods. The UriSed provides for a rapid turnaround time.
Simultaneous removals of NOx, HC and PM from diesel exhaust emissions by dielectric barrier discharges.

PubMed

Song, Chong-Lin; Bin, Feng; Tao, Ze-Min; Li, Fang-Cheng; Huang, Qi-Fei

2009-07-15

The main target of this work is to characterize the abatements of particulate matter (PM), hydrocarbons (HC) and nitrogen oxides (NO(x)) from an actual diesel exhaust using dielectric barrier discharge technology (DBD). The effects of several parameters, such as peak voltage, frequency and engine load, on the contaminant removals have been investigated intensively. The present study shows that for a given frequency, the removals of PM and HC are enhanced with the increase of peak voltage and level off at higher voltage, while in the range of higher voltages a decline of NO(x) removal efficiency is observed. For a given voltage, the maximums of specific energy density (SED) and removal efficiency are attained at resonance point. The increase of peak voltage will result in a significant decrease of energy utilization efficiency of DBD at most engine loads. Alkanes in soluble organic fraction (SOF) are more readily subjected to removals than polycyclic aromatic hydrocarbons (PAHs).
Screwworm Eradication Data System (SEDS) operational manual, part 3

NASA Technical Reports Server (NTRS)

1976-01-01

All phases of SEDS operation as well as utility routines, error messages, and system disk maintenance procedures are described. Display layouts and examples of runs are included as additional explanation to SEDS program procedures.
CMB-induced radio quenching of high-redshift jetted AGNs with highly magnetic hotspots

NASA Astrophysics Data System (ADS)

Wu, Jianfeng; Ghisellini, Gabriele; Hodges-Kluck, Edmund; Gallo, Elena; Ciardi, Benedetta; Haardt, Francesco; Sbarrato, Tullia; Tavecchio, Fabrizio

2017-06-01

In an effort to understand the cause of the apparent depletion in the number density of radio-loud active galactic nuclei (AGNs) at z > 3, this work investigates the viability of the so-called cosmic microwave background (CMB) quenching mechanism of intrinsically jetted, high-z AGNs, whereby inverse Compton scattering of CMB photons off electrons within the extended lobes results in a substantial dimming of the lobe synchrotron emission at GHz frequencies, while simultaneously boosting their diffuse X-ray signal. We focus on five z > 3.5 radio galaxies that have sufficiently deep Chandra exposure (>50 ks) to warrant a meaningful investigation of any extended X-ray emission. For those objects with evidence for statistically significant extended X-ray lobes (4C 41.17 and 4C 03.24), we combine the Chandra measurements with literature data at lower frequencies to assemble the systems' spectral energy distributions (SEDs), and utilize state-of-the-art SED modelling - including emission from the disc, torus, jet, hotspots and lobes - to infer their physical parameters. For both radio galaxies, the magnetic energy density in the hotspots is found to exceed the energy density in CMB photons, whereas the opposite is true for the lobes. This implies that any extended synchrotron emission likely originates from the hotspots themselves, rather than the lobes. Conversely, inverse Compton scattering of CMB photons dominates the extended X-ray emission from the lobes, which are effectively 'radio-quenched'. As a result, CMB quenching is effective in these systems in spite of the fact that the observed X-ray to radio luminosity ratio does not bear the signature (1 + z)4 dependence of the CMB energy density.
The independent prospective associations of activity intensity and dietary energy density with adiposity in young adolescents.

PubMed

van Sluijs, Esther M F; Sharp, Stephen J; Ambrosini, Gina L; Cassidy, Aedin; Griffin, Simon J; Ekelund, Ulf

2016-03-14

There is limited evidence on the prospective association of time spent in activity intensity (sedentary (SED), moderate (MPA) or vigorous (VPA) physical activity) and dietary intake with adiposity indicators in young people. This study aimed to assess associations between (1) baseline objectively measured activity intensity, dietary energy density (DED) and 4-year change in adiposity and (2) 4-year change in activity intensity/DED and adiposity at follow-up. We conducted cohort analyses including 367 participants (10 years at baseline, 14 years at follow-up) with valid data for objectively measured activity (Actigraph), DED (4-d food diary), anthropometry (waist circumference (WC), %body fat (%BF), fat mass index (FMI), weight status) and covariates. Linear and logistic regression models were fit, including adjustment for DED and moderate-to-vigorous physical activity. Results showed that baseline DED was associated with change in WC (β for 1kJ/g difference: 0·71; 95% CI 0·26, 1·17), particularly in boys (1·26; 95% CI 0·41, 2·16 v. girls: 0·26; 95% CI -0·34, 0·87), but not with %BF, FMI or weight status. In contrast, baseline SED, MPA or VPA were not associated with any of the outcomes. Change in DED was negatively associated with FMI (β for 1kJ/g increase: -0·86; 95% CI -1·59, -0·12) and %BF (-0·86; 95% CI -1·25, -0·11) but not WC (-0·27; 95% CI -1·02, 0·48). Change in SED, MPA and VPA did not predict adiposity at follow-up. In conclusion, activity intensity was not prospectively associated with adiposity, whereas the directions of associations with DED were inconsistent. To inform public health efforts, future studies should continue to analyse longitudinal data to further understand the independent role of different energy-balance behaviours in changes in adiposity in early adolescence.
Spitzer Imaging of Strongly lensed Herschel-selected Dusty Star-forming Galaxies

NASA Astrophysics Data System (ADS)

Ma, Brian; Cooray, Asantha; Calanog, J. A.; Nayyeri, H.; Timmons, N.; Casey, C.; Baes, M.; Chapman, S.; Dannerbauer, H.; da Cunha, E.; De Zotti, G.; Dunne, L.; Farrah, D.; Fu, Hai; Gonzalez-Nuevo, J.; Magdis, G.; Michałowski, M. J.; Oteo, I.; Riechers, D. A.; Scott, D.; Smith, M. W. L.; Wang, L.; Wardlow, J.; Vaccari, M.; Viaene, S.; Vieira, J. D.

2015-11-01

We present the rest-frame optical spectral energy distribution (SED) and stellar masses of six Herschel-selected gravitationally lensed dusty, star-forming galaxies (DSFGs) at 1 < z < 3. These galaxies were first identified with Herschel/SPIRE imaging data from the Herschel Astrophysical Terahertz Large Area Survey (H-ATLAS) and the Herschel Multi-tiered Extragalactic Survey (HerMES). The targets were observed with Spitzer/IRAC at 3.6 and 4.5 μm. Due to the spatial resolution of the IRAC observations at the level of 2″, the lensing features of a background DSFG in the near-infrared are blended with the flux from the foreground lensing galaxy in the IRAC imaging data. We make use of higher resolution Hubble/WFC3 or Keck/NIRC2 Adaptive Optics imaging data to fit light profiles of the foreground lensing galaxy (or galaxies) as a way to model the foreground components, in order to successfully disentangle the foreground lens and background source flux densities in the IRAC images. The flux density measurements at 3.6 and 4.5 μm, once combined with Hubble/WFC3 and Keck/NIRC2 data, provide important constraints on the rest-frame optical SED of the Herschel-selected lensed DSFGs. We model the combined UV- to millimeter-wavelength SEDs to establish the stellar mass, dust mass, star formation rate, visual extinction, and other parameters for each of these Herschel-selected DSFGs. These systems have inferred stellar masses in the range 8 × 1010-4 × 1011 M⊙ and star formation rates of around 100 M⊙ yr-1. This puts these lensed submillimeter systems well above the SFR-M* relation observed for normal star-forming galaxies at similar redshifts. The high values of SFR inferred for these systems are consistent with a major merger-driven scenario for star formation.
Biofortification of UK food crops with selenium.

PubMed

Broadley, Martin R; White, Philip J; Bryson, Rosie J; Meacham, Mark C; Bowen, Helen C; Johnson, Sarah E; Hawkesford, Malcolm J; McGrath, Steve P; Zhao, Fang-Jie; Breward, Neil; Harriman, Miles; Tucker, Mark

2006-05-01

Se is an essential element for animals. In man low dietary Se intakes are associated with health disorders including oxidative stress-related conditions, reduced fertility and immune functions and an increased risk of cancers. Although the reference nutrient intakes for adult females and males in the UK are 60 and 75 microg Se/d respectively, dietary Se intakes in the UK have declined from >60 microg Se/d in the 1970s to 35 microg Se/d in the 1990s, with a concomitant decline in human Se status. This decline in Se intake and status has been attributed primarily to the replacement of milling wheat having high levels of grain Se and grown on high-Se soils in North America with UK-sourced wheat having low levels of grain Se and grown on low-Se soils. An immediate solution to low dietary Se intake and status is to enrich UK-grown food crops using Se fertilisers (agronomic biofortification). Such a strategy has been adopted with success in Finland. It may also be possible to enrich food crops in the longer term by selecting or breeding crop varieties with enhanced Se-accumulation characteristics (genetic biofortification). The present paper will review the potential for biofortification of UK food crops with Se.
A Thorough View of the Nuclear Region of NGC 253: Combined Herschel, SOFIA, and APEX Data Set

NASA Astrophysics Data System (ADS)

Pérez-Beaupuits, J. P.; Güsten, R.; Harris, A.; Requena-Torres, M. A.; Menten, K. M.; Weiß, A.; Polehampton, E.; van der Wiel, M. H. D.

2018-06-01

We present a large set of spectral lines detected in the 40″ central region of the starburst galaxy NGC 253. Observations were obtained with the three instruments SPIRE, PACS, and HIFI on board the Herschel Space Observatory, upGREAT on board the SOFIA airborne observatory, and the ground-based Atacama Pathfinder EXperiment telescope. Combining the spectral and photometry products of SPIRE and PACS, we model the dust continuum spectral energy distribution (SED) and the most complete 12CO line SED reported so far toward the nuclear region of NGC 253. The properties and excitation of the molecular gas were derived from a three-component non-LTE radiative transfer model, using the SPIRE 13CO lines and ground-based observations of the lower-J 13CO and HCN lines, to constrain the model parameters. Three dust temperatures were identified from the continuum emission, and three components are needed to fit the full CO line SED. Only the third CO component (fitting mostly the HCN and PACS 12CO lines) is consistent with a shock-/mechanical-heating scenario. A hot core chemistry is also argued as a plausible scenario to explain the high-J 12CO lines detected with PACS. The effect of enhanced cosmic-ray ionization rates, however, cannot be ruled out and is expected to play a significant role in the diffuse and dense gas chemistry. This is supported by the detection of ionic species like OH+ and H2O+, as well as the enhanced fluxes of the OH lines with respect to those of H2O lines detected in both PACS and SPIRE spectra.
Determination of enterotoxigenic and methicillin resistant Staphylococcus aureus in ice cream.

PubMed

Gücükoğlu, Ali; Çadirci, Özgür; Terzi, Göknur; Kevenk, T Onur; Alişarli, Mustafa

2013-05-01

The aim of this study was to determine the prevalence of enterotoxigenic and methicillin-resistant Staphylococcus aureus in ice creams. After culture-based identification of isolates, the presence of 16S rRNA and nuc was confirmed by mPCR. S. aureus was identified in 18 of 56 fruity (32.1%), 4 of 32 vanilla (12.5%), and 1 of 12 chocolate (8.3%) ice creams. S. aureus was identified as 38 isolates in 23 ice cream samples by culture-based techniques, but only 35 isolates were confirmed by PCR as S. aureus. To determine the enterotoxigenic properties of PCR-confirmed S. aureus isolates, a toxin detection kit was used (SET RPLA®). Of the 12 enterotoxigenic S. aureus isolates, 9 SEB (75%), 1 SED (8.3%), 1 SEB+SED (8.3%), and 1 SEA+SEB+SED (8.3%) expressing isolates were found. The presence of enterotoxin genes (sea, seb, sed) was identified in 13 (37.1%) out of 35 isolates by the mPCR technique. In the ice cream isolates, the sea, seb, and sed genes were detected: 1 sea (7.6%), 9 seb (69.2%), 1 sed (7.6%), 1 seb+sed (7.6%), and 1 sea+seb+sed (7.6%), respectively. The sec gene was not detected in any of these isolates. One of the 35 (2.8%) S. aureus strain was mecA positive. © 2013 Institute of Food Technologists®
The Spectral Energy Distribution of the Seyfert Galaxy Ton S180

NASA Technical Reports Server (NTRS)

Turner, T. J.; Romano, P.; Kraemer, S. B.; George, I. M.; Yaqoob, T.; Crenshaw, D. M.; Storm, J.; Alloin, D.; Lazzaro, D.; DaSilva, L.;

2001-01-01

We present spectral results from a multi-satellite, broad-band campaign on the Narrow-line Seyfert 1 galaxy Ton S180 performed at the end of 1999. We discuss the spectral-energy distribution of the source, combining simultaneous Chandra, ASCA and EUVE data with contemporaneous FUSE, HST, and ground-based optical and infrared data. The resulting SED shows that most of the, energy is emitted in the 10 - 100 eV regime, which must be dominated by the primary energy source. No spectral turnover is evident in the UV regime. This, the strong soft X-ray emission, and the overall shape of the SED indicate that emission from the accretion disk peaks between 15 and 100 eV. High resolution FUSE spectra showing UV absorption due to OVI and the lack of detectable X-ray absorption in the Candra spectrum demonstrate the presence of a low column density of highly ionized gas along our line of sight.

Parametric convergence sensitivity and validation of a finite element model of the human lumbar spine.

PubMed

Ayturk, Ugur M; Puttlitz, Christian M

2011-08-01

The primary objective of this study was to generate a finite element model of the human lumbar spine (L1-L5), verify mesh convergence for each tissue constituent and perform an extensive validation using both kinematic/kinetic and stress/strain data. Mesh refinement was accomplished via convergence of strain energy density (SED) predictions for each spinal tissue. The converged model was validated based on range of motion, intradiscal pressure, facet force transmission, anterolateral cortical bone strain and anterior longitudinal ligament deformation predictions. Changes in mesh resolution had the biggest impact on SED predictions under axial rotation loading. Nonlinearity of the moment-rotation curves was accurately simulated and the model predictions on the aforementioned parameters were in good agreement with experimental data. The validated and converged model will be utilised to study the effects of degeneration on the lumbar spine biomechanics, as well as to investigate the mechanical underpinning of the contemporary treatment strategies.
A Summary of Selected Data: DSDP Legs 1-19,

DTIC Science & Technology

1980-09-01

100 minerals may be applied in the future (densi ty water when the mineralogy and attenuation wt. water + wt. dry sed. + salt coefficients become...may be applied in the future when densities of some common minerals are the exact quantitative mineralogy and listed in Harms and Choquette (1965...calculation. These measurements different attenuation coefficient than were used to get a " ball park" answer that of calcite. for a particular sediment type
Iris: Constructing and Analyzing Spectral Energy Distributions with the Virtual Observatory

NASA Astrophysics Data System (ADS)

Laurino, O.; Budynkiewicz, J.; Busko, I.; Cresitello-Dittmar, M.; D'Abrusco, R.; Doe, S.; Evans, J.; Pevunova, O.

2014-05-01

We present Iris 2.0, the latest release of the Virtual Astronomical Observatory application for building and analyzing Spectral Energy Distributions (SEDs). With Iris, users may read in and display SEDs inspect and edit any selection of SED data, fit models to SEDs in arbitrary spectral ranges, and calculate confidence limits on best-fit parameters. SED data may be loaded into the application from VOTable and FITS files compliant with the International Virtual Observatoy Alliance interoperable data models, or retrieved directly from NED or the Italian Space Agency Science Data Center; data in non-standard formats may also be converted within the application. Users may seamlessy exchange data between Iris and other Virtual Observatoy tools using the Simple Application Messaging Protocol. Iris 2.0 also provides a tool for redshifting, interpolating, and measuring integratd fluxes, and allows simple aperture corrections for individual points and SED segments. Custom Python functions, template models and template libraries may be imported into Iris for fitting SEDs. Iris may be extended through Java plugins; users can install third-party packages, or develop their own plugin using Iris' Software Development Kit. Iris 2.0 is available for Linux and Mac OS X systems.
Modeling Well Sampled Composite Spectral Energy Distributions of Distant Galaxies via an MCMC-driven Inference Framework

NASA Astrophysics Data System (ADS)

Pasha, Imad; Kriek, Mariska; Johnson, Benjamin; Conroy, Charlie

2018-01-01

Using a novel, MCMC-driven inference framework, we have modeled the stellar and dust emission of 32 composite spectral energy distributions (SEDs), which span from the near-ultraviolet (NUV) to far infrared (FIR). The composite SEDs were originally constructed in a previous work from the photometric catalogs of the NEWFIRM Medium-Band Survey, in which SEDs of individual galaxies at 0.5 < z < 2.0 were iteratively matched and sorted into types based on their rest-frame UV-to-NIR photometry. In a subsequent work, MIPS 24 μm was added for each SED type, and in this work, PACS 100 μm, PACS160 μm, SPIRE 25 μm, and SPIRE 350 μm photometry have been added to extend the range of the composite SEDs into the FIR. We fit the composite SEDs with the Prospector code, which utilizes an MCMC sampling to explore the parameter space for models created by the Flexible Stellar Population Synthesis (FSPS) code, in order to investigate how specific star formation rate (sSFR), dust temperature, and other galaxy properties vary with SED type.This work is also being used to better constrain the SPS models within FSPS.
A Herschel-SPIRE Survey of the MonR2 Giant Molecular Cloud

NASA Astrophysics Data System (ADS)

Pokhrel, Riwaj; Gutermuth, Robert A.; Ali, Babar; Megeath, S. Thomas; Pipher, Judith; Myers, Philip C.; Fischer, William J.; Henning, Thomas; Wolk, Scott J.; Allen, Lori; Tobin, John J.

2014-06-01

We present a new survey of the MonR2 giant molecular cloud with SPIRE on the Herschel Space Observatory. We cross-calibrated SPIRE data with Planck-HFI and accounted for its absolute offset and zero point correction. We fixed emissivity with the help of flux-error and flux ratio plots. As the best representation of cold dusty molecular clouds, we did greybody fits of the SEDs. We studied the nature of distribution of column densities above and below certain critical limit, followed by the mass and temperature distributions for different regions. We isolated the filaments and studied radial column density profile in this cloud.
Trends in serious emotional disturbance among youths exposed to Hurricane Katrina.

PubMed

McLaughlin, Katie A; Fairbank, John A; Gruber, Michael J; Jones, Russell T; Osofsky, Joy D; Pfefferbaum, Betty; Sampson, Nancy A; Kessler, Ronald C

2010-10-01

To examine patterns and predictors of trends in DSM-IV serious emotional disturbance (SED) among youths exposed to Hurricane Katrina. A probability sample of adult pre-hurricane residents of the areas affected by Katrina completed baseline and follow-up telephone surveys 18 to 27 months post-hurricane and 12 to 18 months later. Baseline adult respondents residing with children and adolescents (4-17 years of age) provided informant reports about the emotional functioning of these youths (n = 576) with the Strengths and Difficulties Questionnaire (SDQ). The surveys also assessed hurricane-related stressors and ongoing stressors experienced by respondent families. SED prevalence decreased significantly across survey waves from 15.1% to 11.5%, although even the latter prevalence was considerably higher than the pre-hurricane prevalence of 4.2% estimated in the US National Health Interview Survey. Trends in hurricane-related SED were predicted by both stressors experienced in the hurricane and ongoing stressors, with SED prevalence decreasing significantly only among youths with moderate stress exposure (16.8% versus 6.5%). SED prevalence did not change significantly between waves among youths with either high stress exposure (30.0% versus 41.9%) or low stress exposure (3.5% versus 3.4%). Pre-hurricane functioning did not predict SED persistence among youths with high stress exposure, but did predict SED persistence among youth with low-moderate stress exposure. The prevalence of SED among youths exposed to Hurricane Katrina remains significantly elevated several years after the storm despite meaningful decrease since baseline. Youths with high stress exposure have the highest risk of long-term hurricane-related SED and consequently represent an important target for mental health intervention. Copyright © 2010 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.
Trends in Serious Emotional Disturbance among Youths Exposed to Hurricane Katrina

PubMed Central

McLaughlin, Katie A.; Fairbank, John A.; Gruber, Michael J.; Jones, Russell T.; Osofsky, Joy D.; Pfefferbaum, Betty; Sampson, Nancy A.; Kessler, Ronald C.

2011-01-01

Objective To examine patterns and predictors of trends in DSM-IV serious emotional disturbance (SED) among youths exposed to Hurricane Katrina. Method A probability sample of adult pre-hurricane residents of the areas affected by Katrina completed baseline and follow-up telephone surveys 18-27 months post-hurricane and 12-18 months later. Baseline adult respondents residing with children (ages 4-17) provided informant reports about the emotional functioning of these youths (n = 576) with the Strengths and Difficulties Questionnaire (SDQ). The surveys also assessed hurricane-related stressors and ongoing stressors experienced by respondent families. Results SED prevalence decreased significantly across survey waves from 15.1% to 11.5%, although even the latter prevalence was considerably higher than the pre-hurricane prevalence of 4.2% estimated in the US National Health Interview Survey. Trends in hurricane-related SED were predicted by both stressors experienced in the hurricane and ongoing stressors, with SED prevalence decreasing significantly only among youths with moderate stress exposure (16.8% vs. 6.5%). SED prevalence did not change significantly between waves among youths with either high stress exposure (30.0% vs. 41.9%) or low stress exposure (3.5% vs. 3.4%). Pre-hurricane functioning did not predict SED persistence among youths with high stress exposure, but did predict SED persistence among youth with low-moderate stress exposure. Conclusions The prevalence of SED among youths exposed to Hurricane Katrina remains significantly elevated several years after the storm despite meaningful decrease since baseline. Youths with high stress exposure have the highest risk of long-term hurricane-related SED and consequently represent an important target for mental health intervention. PMID:20855044
SEDS: The Spitzer Extended Deep Survey. Survey Design, Photometry, and Deep IRAC Source Counts

NASA Technical Reports Server (NTRS)

Ashby, M. L. N.; Willner, S. P.; Fazio, G. G.; Huang, J.-S.; Arendt, A.; Barmby, P.; Barro, G; Bell, E. F.; Bouwens, R.; Cattaneo, A.;

2013-01-01

The Spitzer Extended Deep Survey (SEDS) is a very deep infrared survey within five well-known extragalactic science fields: the UKIDSS Ultra-Deep Survey, the Extended Chandra Deep Field South, COSMOS, the Hubble Deep Field North, and the Extended Groth Strip. SEDS covers a total area of 1.46 deg(exp 2) to a depth of 26 AB mag (3sigma) in both of the warm Infrared Array Camera (IRAC) bands at 3.6 and 4.5 micron. Because of its uniform depth of coverage in so many widely-separated fields, SEDS is subject to roughly 25% smaller errors due to cosmic variance than a single-field survey of the same size. SEDS was designed to detect and characterize galaxies from intermediate to high redshifts (z = 2-7) with a built-in means of assessing the impact of cosmic variance on the individual fields. Because the full SEDS depth was accumulated in at least three separate visits to each field, typically with six-month intervals between visits, SEDS also furnishes an opportunity to assess the infrared variability of faint objects. This paper describes the SEDS survey design, processing, and publicly-available data products. Deep IRAC counts for the more than 300,000 galaxies detected by SEDS are consistent with models based on known galaxy populations. Discrete IRAC sources contribute 5.6 +/- 1.0 and 4.4 +/- 0.8 nW / square m/sr at 3.6 and 4.5 micron to the diffuse cosmic infrared background (CIB). IRAC sources cannot contribute more than half of the total CIB flux estimated from DIRBE data. Barring an unexpected error in the DIRBE flux estimates, half the CIB flux must therefore come from a diffuse component.

Individual, social and environmental factors influencing physical activity levels and behaviours of multiethnic socio-economically disadvantaged urban mothers in Canada: A mixed methods approach

PubMed Central

2012-01-01

Background Existing data provide little insight into the physical activity context of multiethnic socio-economically disadvantaged mothers in Canada. Our primary objectives were: (1) to use focus group methodology to develop tools to identify the individual, social, and environmental factors influencing utilitarian and leisure time physical activities (LTPA) of multiethnic SED mothers; and (2) to use a women specific physical activity survey tool to assess psychosocial barriers and supports and to quantify individual physical activity (PA) levels of multi-ethnic SED mothers in Canada. Methods Qualitative focus group sessions were conducted in West, Central and Eastern Canada with multiethnic SED mothers (n = 6 focus groups; n = 42 SED mothers) and with health and recreation professionals (HRPs) (n = 5 focus groups; n = 25 HRPs) involved in community PA programming for multiethnic SED mothers. Administration of the women specific Kaiser Physical Activity Survey (KPAS) tool was completed by consenting SED mothers (n = 59). Results More than half of SED mothers were employed and had higher total PA scores with occupation included than unemployed mothers. However, nearly 60% of both groups were overweight or obese. Barriers to LTPA included the lack of available, affordable and accessible LTPA programs that responded to cultural and social needs. Concerns for safety, nonsupportive cultural and social norms and the winter climate were identified as key barriers to both utilitarian and LTPA. Conclusions Findings show that multiethnic SED mothers experience many barriers to utilitarian and LTPA opportunities within their communities. The varying LTPA levels among these multi-ethnic SED mothers and the occurrence of overweight and obesity suggests that current LTPA programs are likely insufficient to maintain healthy body weights. PMID:22500882
Are BMI and Sedentariness Correlated? A Multilevel Study in Children

PubMed Central

Gomes, Thayse Natacha; Katzmarzyk, Peter T.; dos Santos, Fernanda Karina; de Chaves, Raquel Nichele; Santos, Daniel; Pereira, Sara; Champagne, Catherine M.; Hedeker, Donald; Maia, José

2015-01-01

The purpose of this research was to investigate the relationship between body mass index (BMI) and sedentariness (Sed) in children and to examine the influence of child and school correlates on their variation. The sample comprises 580 children (337 girls, 9–11 years). Sedentariness was assessed with an accelerometer, and BMI was computed. Child- and school-level covariates were analyzed using multilevel models. No significant correlation between Sed and BMI was found. School context explains 5% and 1.5% of the total variance in Sed and BMI, respectively. At the child level, only moderate-to-vigorous physical activity was associated with both Sed (β = −0.02 ± 0.002) and BMI (β = −0.005 ± 0.002). Sleep time is related to Sed (β = −0.42 ± 0.04), while sex (β = 1.97 ± 0.13), biological maturity (β = 1.25 ± 0.07), media in the bedroom (β = 0.26 ± 0.08) and healthy (β = −0.09 ± 0.03) and unhealthy (β = −0.07 ± 0.04) diet scores were associated with BMI. None of the school-level covariates were related to BMI, but access to cafeteria (β = −0.97 ± 0.25), playground equipment (β = −0.67 ± 0.20) and restaurants (β = 0.16 ± 0.08) were related to Sed. In conclusion, Sed and BMI were not correlated. Further, they have different correlates, while children’s traits seem to play more relevant roles in their differences in Sed and BMI than the school milieu. This information should be taken into account when strategies to reduce Sed and BMI are implemented. PMID:26193311
Reproducible computational biology experiments with SED-ML--the Simulation Experiment Description Markup Language.

PubMed

Waltemath, Dagmar; Adams, Richard; Bergmann, Frank T; Hucka, Michael; Kolpakov, Fedor; Miller, Andrew K; Moraru, Ion I; Nickerson, David; Sahle, Sven; Snoep, Jacky L; Le Novère, Nicolas

2011-12-15

The increasing use of computational simulation experiments to inform modern biological research creates new challenges to annotate, archive, share and reproduce such experiments. The recently published Minimum Information About a Simulation Experiment (MIASE) proposes a minimal set of information that should be provided to allow the reproduction of simulation experiments among users and software tools. In this article, we present the Simulation Experiment Description Markup Language (SED-ML). SED-ML encodes in a computer-readable exchange format the information required by MIASE to enable reproduction of simulation experiments. It has been developed as a community project and it is defined in a detailed technical specification and additionally provides an XML schema. The version of SED-ML described in this publication is Level 1 Version 1. It covers the description of the most frequent type of simulation experiments in the area, namely time course simulations. SED-ML documents specify which models to use in an experiment, modifications to apply on the models before using them, which simulation procedures to run on each model, what analysis results to output, and how the results should be presented. These descriptions are independent of the underlying model implementation. SED-ML is a software-independent format for encoding the description of simulation experiments; it is not specific to particular simulation tools. Here, we demonstrate that with the growing software support for SED-ML we can effectively exchange executable simulation descriptions. With SED-ML, software can exchange simulation experiment descriptions, enabling the validation and reuse of simulation experiments in different tools. Authors of papers reporting simulation experiments can make their simulation protocols available for other scientists to reproduce the results. Because SED-ML is agnostic about exact modeling language(s) used, experiments covering models from different fields of research can be accurately described and combined.
[Swim training attenuates myocardial remodeling and the pulmonary congestion in wistar rats with secondary heart failure to myocardial infarction].

PubMed

Portes, Leslie Andrews; Tucci, Paulo José Ferreira

2006-07-01

To evaluate the effects of swimming on pulmonary water content in animals with heart failure (HF) after myocardial infarction (MI). After coronary occlusion, MI size 20% 40% of the LV large. The animals swam for 60 min/day, 5 days/week for 8 weeks. The wet weight of lung, liver, atriums, LV and right ventricle (RV) as well as the dry weight of the liver and lung were determined. ANOVA and Tukey test were used for statistical analysis. An increase in the atrium/body weight ratio was noted in the sedentary animals with moderate (MImod-SED: n=8) and large (MIlg-SED: n=10) infarctions in comparison to the sedentary control (C-SED: n=14) and trained (C-TR: n=16) rats. An increase in the RV/body weight and LV/body weight ratios was noted in the MIlg-SED. The heart/body weight ratio was higher in MIlg-SED when compared to the other groups. The infarcted trained animals presented diminished hypertrophy. The pulmonary water content was higher in MIlg-SED animals (81+/-0.4%) than in C-SED animals (79+/-0.4%). No differences were found for the other comparisons (C-TR: 79+/-0.4%; MImod-SED: 80+/-0.3%; MImod-TR: 80+/-0.6%; MIlg-TR: 79+/-0.7%). The increase of cardiac mass and pulmonary water content presented by MIlg-SED was diminished in the trained animals. The results suggest that the practice of physical exercise can diminish HF and contribute to favorable cardiac remodeling.
Empirical Orthogonal Function (EOF) Analysis of Storm-Time GPS Total Electron Content Variations

NASA Astrophysics Data System (ADS)

Thomas, E. G.; Coster, A. J.; Zhang, S.; McGranaghan, R. M.; Shepherd, S. G.; Baker, J. B.; Ruohoniemi, J. M.

2016-12-01

Large perturbations in ionospheric density are known to occur during geomagnetic storms triggered by dynamic structures in the solar wind. These ionospheric storm effects have long attracted interest due to their impact on the propagation characteristics of radio wave communications. Over the last two decades, maps of vertically-integrated total electron content (TEC) based on data collected by worldwide networks of Global Positioning System (GPS) receivers have dramatically improved our ability to monitor the spatiotemporal dynamics of prominent storm-time features such as polar cap patches and storm enhanced density (SED) plumes. In this study, we use an empirical orthogonal function (EOF) decomposition technique to identify the primary modes of spatial and temporal variability in the storm-time GPS TEC response at midlatitudes over North America during more than 100 moderate geomagnetic storms from 2001-2013. We next examine the resulting time-varying principal components and their correlation with various geophysical indices and parameters in order to derive an analytical representation. Finally, we use a truncated reconstruction of the EOF basis functions and parameterization of the principal components to produce an empirical representation of the geomagnetic storm-time response of GPS TEC for all magnetic local times local times and seasons at midlatitudes in the North American sector.
Quasar Spectral Energy Distributions As A Function Of Physical Property

NASA Astrophysics Data System (ADS)

Townsend, Shonda; Ganguly, R.; Stark, M. A.; Derseweh, J. A.; Richmond, J. M.

2012-05-01

Galaxy evolution models have shown that quasars are a crucial ingredient in the evolution of massive galaxies. Outflows play a key role in the story of quasars and their host galaxies, by helping regulate the accretion process, the star-formation rate and mass of the host galaxy (i.e., feedback). The prescription for modeling outflows as a contributor to feedback requires knowledge of the outflow velocity, geometry, and column density. In particular, we need to understand how these depend on physical parameters and how much is determined stochastically (and with what distribution). In turn, models of outflows have shown particular sensitivity to the shape of the spectral energy distribution (SED), depending on the UV luminosity to transfer momentum to the gas, the X-ray luminosity to regulate how efficiently that transfer can be, etc. To investigate how SED changes with physical properties, we follow up on Richards et al. (2006), who constructed SEDs with varying luminosity. Here, we construct SEDs as a function of redshift, and physical property (black hole mass, bolometric luminosity, Eddington ratio) for volume limited samples drawn from the Sloan Digital Sky Survey, with photometry supplemented from 2MASS, WISE, GALEX, ROSAT, and Chandra. To estimate black hole masses, we adopt the scaling relations from Greene & Ho (2005) based on the H-alpha emission line FWHM. This requires redshifts less than 0.4. To construct volume-limited subsamples, we begin by adopting g=19.8 as a nominal limiting magnitude over which we are guaranteed to detect z<0.4 quasars. At redshift 0.4, we are complete down to Mg=-21.8, which yields 3300 objects from Data Release 7. At z=0.1, we are complete down to Mg=-18.5. This material is based upon work supported by the National Aeronautics and Space Administration under Grant No. 09-ADP09-0016 issued through the Astrophysics Data Analysis Program.
Neighborhood Sociodemographic Predictors of Serious Emotional Disturbance (SED) in Schools: Demonstrating a Small Area Estimation Method in the National Comorbidity Survey (NCS-A) Adolescent Supplement

PubMed Central

Alegría, Margarita; Kessler, Ronald C.; McLaughlin, Katie A.; Gruber, Michael J.; Sampson, Nancy A.; Zaslavsky, Alan M.

2014-01-01

We evaluate the precision of a model estimating school prevalence of SED using a small area estimation method based on readily-available predictors from area-level census block data and school principal questionnaires. Adolescents at 314 schools participated in the National Comorbidity Supplement, a national survey of DSM-IV disorders among adolescents. A multilevel model indicated that predictors accounted for under half of the variance in school-level SED and even less when considering block-group predictors or principal report alone. While Census measures and principal questionnaires are significant predictors of individual-level SED, associations are too weak to generate precise school-level predictions of SED prevalence. PMID:24740174
The Reliability of Psychiatric Diagnosis Revisited

PubMed Central

Rankin, Eric; France, Cheryl; El-Missiry, Ahmed; John, Collin

2006-01-01

Background: The authors reviewed the topic of reliability of psychiatric diagnosis from the turn of the 20th century to present. The objectives of this paper are to explore the reasons of unreliability of psychiatric diagnosis and propose ways to improve the reliability of psychiatric diagnosis. Method: The authors reviewed the literature on the concept of reliability of psychiatric diagnosis with emphasis on the impact of interviewing skills, use of diagnostic criteria, and structured interviews on the reliability of psychiatric diagnosis. Results: Causes of diagnostic unreliability are attributed to the patient, the clinician and psychiatric nomenclature. The reliability of psychiatric diagnosis can be enhanced by using diagnostic criteria, defining psychiatric symptoms and structuring the interviews. Conclusions: The authors propose the acronym ‘DR.SED,' which stands for diagnostic criteria, reference definitions, structuring the interview, clinical experience, and data. The authors recommend that clinicians use the DR.SED paradigm to improve the reliability of psychiatric diagnoses. PMID:21103149
Seasonal variations and sources of sedimentary organic carbon in Tokyo Bay.

PubMed

Kubo, Atsushi; Kanda, Jota

2017-01-30

Total organic carbon (TOC), total nitrogen (TN) contents, their stable C and N isotope ratio (δ 13 C and δ 15 N), and chlorophyll a ([Chl a] sed ) of surface sediments were investigated monthly to identify the seasonal variations and sources of organic matter in Tokyo Bay. The sedimentary TOC (TOC sed ) and TN (TN sed ) contents, and the sedimentary δ 13 C and δ 15 N (δ 13 C sed and δ 15 N sed ) values were higher in summer than other seasons. The seasonal variations were controlled by high primary production in the water column and hypoxic water in the bottom water during summer. The fraction of terrestrial and marine derived organic matter was estimated by Bayesian mixing model using stable isotope data and TOC/TN ratio. Surface sediments in Tokyo Bay are dominated by marine derived organic matter, which accounts for about 69±5% of TOC sed . Copyright © 2016 Elsevier Ltd. All rights reserved.
sedFlow - an efficient tool for simulating bedload transport, bed roughness, and longitudinal profile evolution in mountain streams

NASA Astrophysics Data System (ADS)

Heimann, F. U. M.; Rickenmann, D.; Turowski, J. M.; Kirchner, J. W.

2014-07-01

Especially in mountainuous environments, the prediction of sediment dynamics is important for managing natural hazards, assessing in-stream habitats, and understanding geomorphic evolution. We present the new modelling tool sedFlow for simulating fractional bedload transport dynamics in mountain streams. The model can deal with the effects of adverse slopes and uses state of the art approaches for quantifying macro-roughness effects in steep channels. Local grain size distributions are dynamically adjusted according to the transport dynamics of each grain size fraction. The tool sedFlow features fast calculations and straightforward pre- and postprocessing of simulation data. The model is provided together with its complete source code free of charge under the terms of the GNU General Public License (www.wsl.ch/sedFlow). Examples of the application of sedFlow are given in a companion article by Heimann et al. (2014).
THE LUMINOSITY FUNCTION OF FERMI-DETECTED FLAT-SPECTRUM RADIO QUASARS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ajello, M.; Shaw, M. S.; Romani, R. W.

2012-06-01

Fermi has provided the largest sample of {gamma}-ray-selected blazars to date. In this work we use a complete sample of flat spectrum radio quasars (FSRQs) detected during the first year of operation to determine the luminosity function (LF) and its evolution with cosmic time. The number density of FSRQs grows dramatically up to redshift {approx}0.5-2.0 and declines thereafter. The redshift of the peak in the density is luminosity dependent, with more luminous sources peaking at earlier times; thus the LF of {gamma}-ray FSRQs follows a luminosity-dependent density evolution similar to that of radio-quiet active galactic nuclei. Also, using data frommore » the Swift Burst Alert Telescope we derive the average spectral energy distribution (SED) of FSRQs in the 10 keV-300 GeV band and show that there is no correlation between the luminosity at the peak of the {gamma}-ray emission component and its peak frequency. Using this luminosity-independent SED with the derived LF allows us to predict that the contribution of FSRQs to the Fermi isotropic {gamma}-ray background is 9.3{sup +1.6}{sub -1.0}% ({+-}3% systematic uncertainty) in the 0.1-100 GeV band. Finally we determine the LF of unbeamed FSRQs, finding that FSRQs have an average Lorentz factor of {gamma} = 11.7{sup +3.3}{sub -2.2}, that most are seen within 5 Degree-Sign of the jet axis, and that they represent only {approx}0.1% of the parent population.« less
Cassini Radio and Plasma Wave Observations at Saturn

NASA Technical Reports Server (NTRS)

Gurnett, D. A.; Kurth, W. S.; Hospodarsky, G. B.; Persoon, A. M.; Averkamp, T. F.; Ceccni, B.; Lecacheux, A.; Zarka, P.; Canu, P.; Cornilleau-Wehrlin, N.

2005-01-01

Results are presented from the Cassini radio and plasma wave instrument during the approach and first few orbits around Saturn. During the approach the intensity modulation of Saturn Kilometric Radiation (SKR) showed that the radio rotation period of Saturn has increased to 10 hr 45 min plus or minus 36 sec, about 6 min longer than measured by Voyager in 1980-81. Also, many intense impulsive radio signals called Saturn Electrostatic Discharges (SEDs) were detected from saturnian lightning, starting as far as 1.08 AU from Saturn, much farther than terrestrial lightning can be detected from Earth. Some of the SED episodes have been linked to cloud systems observed in Saturn s atmosphere by the Cassini imaging system. Within the magnetosphere plasma wave emissions have been used to construct an electron density profile through the inner region of the magnetosphere. With decreasing radial distance the electron density increases gradually to a peak of about 100 per cubic centimeter near the outer edge of the A ring, and then drops precipitously to values as low as .03 per cubic centimeter over the rings. Numerous nearly monochromatic whistler-mode emissions were observed as the spacecraft passed over the rings that are believed to be produced by meteoroid impacts on the rings. Whistlermode emissions, similar to terrestrial auroral hiss were also observed over the rings, indicating that an electrodynamic interaction, similar to auroral particle acceleration, may be occurring in or near the rings. During the Titan flybys Langmuir probe and plasma wave measurements provided observations of the density and temperature in Titan's ionosphere.

GAMMA–GAMMA ABSORPTION IN THE BROAD LINE REGION RADIATION FIELDS OF GAMMA-RAY BLAZARS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Böttcher, Markus; Els, Paul, E-mail: Markus.Bottcher@nwu.ac.za

2016-04-20

The expected level of γγ absorption in the Broad Line Region (BLR) radiation field of γ -ray loud Flat Spectrum Radio Quasars (FSRQs) is evaluated as a function of the location of the γ -ray emission region. This is done self-consistently with parameters inferred from the shape of the spectral energy distribution (SED) in a single-zone leptonic EC-BLR model scenario. We take into account all geometrical effects both in the calculation of the γγ opacity and the normalization of the BLR radiation energy density. As specific examples, we study the FSRQs 3C279 and PKS 1510-089, keeping the BLR radiation energymore » density at the location of the emission region fixed at the values inferred from the SED. We confirm previous findings that the optical depth due to γγ absorption in the BLR radiation field exceeds unity for both 3C279 and PKS 1510-089 for locations of the γ -ray emission region inside the inner boundary of the BLR. It decreases monotonically, with distance from the central engine and drops below unity for locations within the BLR. For locations outside the BLR, the BLR radiation energy density required for the production of GeV γ -rays rapidly increases beyond observational constraints, thus making the EC-BLR mechanism implausible. Therefore, in order to avoid significant γγ absorption by the BLR radiation field, the γ -ray emission region must therefore be located near the outer boundary of the BLR.« less
Radial Surface Density Profiles of Gas and Dust in the Debris Disk around 49 Ceti

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hughes, A. Meredith; Lieman-Sifry, Jesse; Flaherty, Kevin M.

We present ∼0.″4 resolution images of CO(3–2) and associated continuum emission from the gas-bearing debris disk around the nearby A star 49 Ceti, observed with the Atacama Large Millimeter/Submillimeter Array (ALMA). We analyze the ALMA visibilities in tandem with the broadband spectral energy distribution to measure the radial surface density profiles of dust and gas emission from the system. The dust surface density decreases with radius between ∼100 and 310 au, with a marginally significant enhancement of surface density at a radius of ∼110 au. The SED requires an inner disk of small grains in addition to the outer diskmore » of larger grains resolved by ALMA. The gas disk exhibits a surface density profile that increases with radius, contrary to most previous spatially resolved observations of circumstellar gas disks. While ∼80% of the CO flux is well described by an axisymmetric power-law disk in Keplerian rotation about the central star, residuals at ∼20% of the peak flux exhibit a departure from axisymmetry suggestive of spiral arms or a warp in the gas disk. The radial extent of the gas disk (∼220 au) is smaller than that of the dust disk (∼300 au), consistent with recent observations of other gas-bearing debris disks. While there are so far only three broad debris disks with well characterized radial dust profiles at millimeter wavelengths, 49 Ceti’s disk shows a markedly different structure from two radially resolved gas-poor debris disks, implying that the physical processes generating and sculpting the gas and dust are fundamentally different.« less
Understanding the scatter in the spatially resolved star formation main sequence of local massive spiral galaxies

NASA Astrophysics Data System (ADS)

Abdurro'uf; Akiyama, Masayuki

2017-08-01

We investigate the relation between star formation rate (SFR) and stellar mass (M*) at the sub-galactic scale (˜1 kpc) of 93 local (0.01 < z < 0.02) massive (M* > 1010.5 M⊙) spiral galaxies. To derive a spatially resolved SFR and stellar mass, we perform the so-called pixel-to-pixel spectral energy distribution (SED) fitting, which fits an observed spatially resolved multiband SED with a library of model SEDs using Bayesian statistics. We use two bands (far-ultraviolet or FUV and near-ultraviolet or NUV) and five bands (u, g, r, I and z) of imaging data from Galaxy Evolution Explorer (GALEX) and Sloan Digital Sky Survey (SDSS), respectively. We find a tight nearly linear relation between the local surface density of SFR (ΣSFR) and stellar mass (Σ*), which is flattened at high Σ*. The near linear relation between Σ* and ΣSFR suggests a constant specific SFR (sSFR) throughout the galaxies, and the scatter of the relation is directly related to that of the sSFR. Therefore, we analyse the variation of the sSFR in various scales. More massive galaxies on average have lower sSFR throughout them than less massive galaxies. We also find that barred galaxies have a lower sSFR in the core region than non-barred galaxies. However, in the outer region, the sSFRs of barred and non-barred galaxies are similar and lead to a similar total sSFR.
The Spectral Energy Distributions and Infrared Luminosities of z ≈ 2 Dust-obscured Galaxies from Herschel and Spitzer

NASA Astrophysics Data System (ADS)

Melbourne, J.; Soifer, B. T.; Desai, Vandana; Pope, Alexandra; Armus, Lee; Dey, Arjun; Bussmann, R. S.; Jannuzi, B. T.; Alberts, Stacey

2012-05-01

Dust-obscured galaxies (DOGs) are a subset of high-redshift (z ≈ 2) optically-faint ultra-luminous infrared galaxies (ULIRGs, e.g., L IR > 1012 L ⊙). We present new far-infrared photometry, at 250, 350, and 500 μm (observed-frame), from the Herschel Space Telescope for a large sample of 113 DOGs with spectroscopically measured redshifts. Approximately 60% of the sample are detected in the far-IR. The Herschel photometry allows the first robust determinations of the total infrared luminosities of a large sample of DOGs, confirming their high IR luminosities, which range from 1011.6 L ⊙ 1013 L ⊙. The rest-frame near-IR (1-3 μm) spectral energy distributions (SEDs) of the Herschel-detected DOGs are predictors of their SEDs at longer wavelengths. DOGs with "power-law" SEDs in the rest-frame near-IR show observed-frame 250/24 μm flux density ratios similar to the QSO-like local ULIRG, Mrk 231. DOGs with a stellar "bump" in their rest-frame near-IR show observed-frame 250/24 μm flux density ratios similar to local star-bursting ULIRGs like NGC 6240. None show 250/24 μm flux density ratios similar to extreme local ULIRG, Arp 220; though three show 350/24 μm flux density ratios similar to Arp 220. For the Herschel-detected DOGs, accurate estimates (within ~25%) of total IR luminosity can be predicted from their rest-frame mid-IR data alone (e.g., from Spitzer observed-frame 24 μm luminosities). Herschel-detected DOGs tend to have a high ratio of infrared luminosity to rest-frame 8 μm luminosity (the IR8 = L IR(8-1000 μm)/νL ν(8 μm) parameter of Elbaz et al.). Instead of lying on the z = 1-2 "infrared main sequence" of star-forming galaxies (like typical LIRGs and ULIRGs at those epochs) the DOGs, especially large fractions of the bump sources, tend to lie in the starburst sequence. While, Herschel-detected DOGs are similar to scaled up versions of local ULIRGs in terms of 250/24 μm flux density ratio, and IR8, they tend to have cooler far-IR dust temperatures (20-40 K for DOGs versus 40-50 K for local ULIRGs) as measured by the rest-frame 80/115 μm flux density ratios (e.g., observed-frame 250/350 μm ratios at z = 2). DOGs that are not detected by Herschel appear to have lower observed-frame 250/24 μm ratios than the detected sample, either because of warmer dust temperatures, lower IR luminosities, or both. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.
THE SPECTRAL ENERGY DISTRIBUTIONS AND INFRARED LUMINOSITIES OF z Almost-Equal-To 2 DUST-OBSCURED GALAXIES FROM Herschel AND Spitzer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Melbourne, J.; Soifer, B. T.; Desai, Vandana

Dust-obscured galaxies (DOGs) are a subset of high-redshift (z Almost-Equal-To 2) optically-faint ultra-luminous infrared galaxies (ULIRGs, e.g., L{sub IR} > 10{sup 12} L{sub Sun} ). We present new far-infrared photometry, at 250, 350, and 500 {mu}m (observed-frame), from the Herschel Space Telescope for a large sample of 113 DOGs with spectroscopically measured redshifts. Approximately 60% of the sample are detected in the far-IR. The Herschel photometry allows the first robust determinations of the total infrared luminosities of a large sample of DOGs, confirming their high IR luminosities, which range from 10{sup 11.6} L{sub Sun} 10{sup 13} L{sub Sun }. Themore » rest-frame near-IR (1-3 {mu}m) spectral energy distributions (SEDs) of the Herschel-detected DOGs are predictors of their SEDs at longer wavelengths. DOGs with 'power-law' SEDs in the rest-frame near-IR show observed-frame 250/24 {mu}m flux density ratios similar to the QSO-like local ULIRG, Mrk 231. DOGs with a stellar 'bump' in their rest-frame near-IR show observed-frame 250/24 {mu}m flux density ratios similar to local star-bursting ULIRGs like NGC 6240. None show 250/24 {mu}m flux density ratios similar to extreme local ULIRG, Arp 220; though three show 350/24 {mu}m flux density ratios similar to Arp 220. For the Herschel-detected DOGs, accurate estimates (within {approx}25%) of total IR luminosity can be predicted from their rest-frame mid-IR data alone (e.g., from Spitzer observed-frame 24 {mu}m luminosities). Herschel-detected DOGs tend to have a high ratio of infrared luminosity to rest-frame 8 {mu}m luminosity (the IR8 = L{sub IR}(8-1000 {mu}m)/{nu}L{sub {nu}}(8 {mu}m) parameter of Elbaz et al.). Instead of lying on the z = 1-2 'infrared main sequence' of star-forming galaxies (like typical LIRGs and ULIRGs at those epochs) the DOGs, especially large fractions of the bump sources, tend to lie in the starburst sequence. While, Herschel-detected DOGs are similar to scaled up versions of local ULIRGs in terms of 250/24 {mu}m flux density ratio, and IR8, they tend to have cooler far-IR dust temperatures (20-40 K for DOGs versus 40-50 K for local ULIRGs) as measured by the rest-frame 80/115 {mu}m flux density ratios (e.g., observed-frame 250/350 {mu}m ratios at z = 2). DOGs that are not detected by Herschel appear to have lower observed-frame 250/24 {mu}m ratios than the detected sample, either because of warmer dust temperatures, lower IR luminosities, or both.« less
Opening the Floodgates? The Social Maladjustment Exclusion and State SED Prevalence Rates.

ERIC Educational Resources Information Center

Skiba, Russell; And Others

1994-01-01

Surveyed state special education directors in 50 states and District of Columbia regarding social maladjustment exclusionary clause in federal definition of serious emotional disturbance (SED). Thirty-four states included social maladjustment clause or some form of exclusion in SED definition. Found no significant relationship between presence of…
Research Staff | Research Site Name | NREL

Science.gov Websites

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15 CFR 758.5 - Conformity of documents and unloading of items.

Code of Federal Regulations, 2011 CFR

2011-01-01

... and Shipper's Export Declaration (SED) or AES electronic equivalent. (2) Optional ports of unloading... ultimate destination or are included on the BIS license and SED or AES electronic equivalent. (ii... ports of unloading on the SED or AES electronic equivalent and other export control documents, so long...
15 CFR 758.5 - Conformity of documents and unloading of items.

Code of Federal Regulations, 2013 CFR

2013-01-01

...., the SED or AES record, bill of lading or air waybill) must be consistent with the license. (c... and Shipper's Export Declaration (SED) or AES electronic equivalent. (2) Optional ports of unloading... ultimate destination or are included on the BIS license and SED or AES electronic equivalent. (ii...
15 CFR 758.5 - Conformity of documents and unloading of items.

Code of Federal Regulations, 2012 CFR

2012-01-01

...., the SED or AES record, bill of lading or air waybill) must be consistent with the license. (c... and Shipper's Export Declaration (SED) or AES electronic equivalent. (2) Optional ports of unloading... ultimate destination or are included on the BIS license and SED or AES electronic equivalent. (ii...
SED/Apple Computer, Inc., Partnership Program.

ERIC Educational Resources Information Center

Stoll, Peter F.

1991-01-01

In 1990, the New York State Education Department (SED), Apple Computer, Inc., Boards of Cooperative Educational Services (BOCES), and school districts formed a partnership to explore the contribution technology can make to schools based on Apple Computer's Learning Society and SED's Long-Range Plan for Technology in Elementary and Secondary…
What can the SEDs of first hydrostatic core candidates reveal about their nature?

NASA Astrophysics Data System (ADS)

Young, Alison K.; Bate, Matthew R.; Mowat, Chris F.; Hatchell, Jennifer; Harries, Tim J.

2018-02-01

The first hydrostatic core (FHSC) is the first stable object to form in simulations of star formation. This stage has yet to be observed definitively, although several candidate FHSCs have been reported. We have produced synthetic spectral energy distributions (SEDs) from 3D hydrodynamical simulations of pre-stellar cores undergoing gravitational collapse for a variety of initial conditions. Variations in the initial rotation rate, radius and mass lead to differences in the location of the SED peak and far-infrared flux. Secondly, we attempt to fit the SEDs of five FHSC candidates from the literature and five newly identified FHSC candidates located in the Serpens South molecular cloud with simulated SEDs. The most promising FHSC candidates are fitted by a limited number of model SEDs with consistent properties, which suggests that the SED can be useful for placing constraints on the age and rotation rate of the source. The sources we consider most likely to be in FHSC phase are B1-bN, CB17-MMS, Aqu-MM1 and Serpens South candidate K242. We were unable to fit SerpS-MM22, Per-Bolo 58 and Chamaeleon-MMS1 with reasonable parameters, which indicates that they are likely to be more evolved.
Artist's Concept of Propulsive Small Expendable Deployer System (ProSEDS)

NASA Technical Reports Server (NTRS)

1999-01-01

Pictured is an artist's concept of NASA's Propulsive Small Expendable Deployer System experiment (ProSEDS). ProSEDS will demonstrate the use of an electrodynamic tether, basically a long, thin wire, for propulsion. An electrodynamic tether uses the same principles as electric motors in toys, appliances and computer disk drives, and generators in automobiles and power plants. When electrical current is flowing through the tether, a magnetic field is produced that pushes against the magnetic field of the Earth. For ProSEDS, the current in the tether results by virtue of the voltage generated when the tether moves through the Earth's magnetic field at more than 17,000 mph. This approach can produce drag thrust generating useable power. Since electrodynamic tethers require no propellant, they could substantially reduce the weight of the spacecraft and provide a cost-effective method of reboosting spacecraft. The initial flight of ProSEDS is scheduled to fly aboard an Air Force Delta II rocket in summer of 2002. In orbit, ProSEDS will deploy from a Delta II second stage. It will be a 3.1-mile (5 kilometer) long, ultrathin base-wire tether cornected with a 6.2-mile (10 kilometer) long nonconducting tether. The ProSEDS experiment is managed by the Space Transportation Directorate at the Marshall Space Flight Center.
Impact of low-volume, high-intensity interval training on maximal aerobic capacity, health-related quality of life and motivation to exercise in ageing men.

PubMed

Knowles, Ann-Marie; Herbert, Peter; Easton, Chris; Sculthorpe, Nicholas; Grace, Fergal M

2015-01-01

There is a demand for effective training methods that encourage exercise adherence during advancing age, particularly in sedentary populations. This study examined the effects of high-intensity interval training (HIIT) exercise on health-related quality of life (HRQL), aerobic fitness and motivation to exercise in ageing men. Participants consisted of males who were either lifelong sedentary (SED; N = 25; age 63 ± 5 years) or lifelong exercisers (LEX; N = 19; aged 61 ± 5 years). [Formula: see text] and HRQL were measured at three phases: baseline (Phase A), week seven (Phase B) and week 13 (Phase C). Motivation to exercise was measured at baseline and week 13. [Formula: see text] was significantly higher in LEX (39.2 ± 5.6 ml kg min(-1)) compared to SED (27.2 ± 5.2 ml kg min(-1)) and increased in both groups from Phase A to C (SED 4.6 ± 3.2 ml kg min(-1), 95 % CI 3.1 - 6.0; LEX 4.9 ± 3.4 ml kg min(-1), 95 % CI 3.1-6.6) Physical functioning (97 ± 4 LEX; 93 ± 7 SED) and general health (70 ± 11 LEX; 78 ± 11 SED) were significantly higher in LEX but increased only in the SED group from Phase A to C (physical functioning 17 ± 18, 95 % CI 9-26, general health 14 ± 14, 95 % CI 8-21). Exercise motives related to social recognition (2.4 ± 1.2 LEX; 1.5 ± 1.0 SED), affiliation (2.7 ± 1.0 LEX; 1.6 ± 1.2 SED) and competition (3.3 ± 1.3 LEX; 2.2 ± 1.1) were significantly higher in LEX yet weight management motives were significantly higher in SED (2.9 ± 1.1 LEX; 4.3 ± 0.5 SED). The study provides preliminary evidence that low-volume HIIT increases perceptions of HRQL, exercise motives and aerobic capacity in older adults, to varying degrees, in both SED and LEX groups.
Formation of methotrexate-PLLA-PEG-PLLA composite microspheres by microencapsulation through a process of suspension-enhanced dispersion by supercritical CO2

PubMed Central

Chen, Ai-Zheng; Wang, Guang-Ya; Wang, Shi-Bin; Li, Li; Liu, Yuan-Gang; Zhao, Chen

2012-01-01

Background The aim of this study was to improve the drug loading, encapsulation efficiency, and sustained-release properties of supercritical CO2-based drug-loaded polymer carriers via a process of suspension-enhanced dispersion by supercritical CO2 (SpEDS), which is an advanced version of solution-enhanced dispersion by supercritical CO2 (SEDS). Methods Methotrexate nanoparticles were successfully microencapsulated into poly (L-lactide)-poly(ethylene glycol)-poly(L-lactide) (PLLA-PEG-PLLA) by SpEDS. Methotrexate nanoparticles were first prepared by SEDS, then suspended in PLLA-PEG-PLLA solution, and finally microencapsulated into PLLA-PEG-PLLA via SpEDS, where an “injector” was utilized in the suspension delivery system. Results After microencapsulation, the composite methotrexate (MTX)-PLLA-PEG-PLLA microspheres obtained had a mean particle size of 545 nm, drug loading of 13.7%, and an encapsulation efficiency of 39.2%. After an initial burst release, with around 65% of the total methotrexate being released in the first 3 hours, the MTX-PLLA-PEG-PLLA microspheres released methotrexate in a sustained manner, with 85% of the total methotrexate dose released within 23 hours and nearly 100% within 144 hours. Conclusion Compared with a parallel study of the coprecipitation process, microencapsulation using SpEDS offered greater potential to manufacture drug-loaded polymer microspheres for a drug delivery system. PMID:22787397
The Role of Seismic Directivity in Tele-seismically Induced Well Level Oscillations

NASA Astrophysics Data System (ADS)

Voss, N. K.; Wdowinski, S.

2013-12-01

Surface waves induced by large earthquakes travel large distances around the globe and can cause disturbances in ground water systems as they pass. Their most minimal disturbance is manifested through oscillations of hydraulic head in wells. In order to understand what controls well oscillatory response, we examine hydrograph records from 22 wells in South Florida's Floridan aquifer, which were acquired over a nine-year period (June 2003 - September 2012). We found a regional threshold of Mo=6.9 earthquakes for inducing well oscillations. Our record includes 99 main shock events at or above this magnitude. As the induced oscillations also depend on the distance between the earthquake and the well, we applied the commonly used Seismic Energy Density (SED) parameter [Wang and Manga 2010;Wang 2007;Wang 2008] and investigate the relationship between SED and well oscillations. The minimum SED value of events with oscillations in our data set was 0.002 j/m3. Wang and Manga [2010] found a similar value of 0.001 j/m3 for sustained groundwater change, very close to our observations for transient changes. However, our threshold value did not guarantee a well oscillatory response. In the South Florida well dataset only 16% of events with SED values at or above 0.002 j/m3 showed hydraulic head oscillation. When looking at events with SED of 0.005 j/m3 or above, 55% of events (16 out of 29) showed oscillations in hydraulic head. In this research we explore other parameters beside earthquake magnitude and distance to the well that can explain why 45% of events with SED>0.005 j/m3 still showed no oscillatory response. We hypothesize that inconsistent oscillatory response reflects the effect of seismic directivity. Direct calculation of Rayleigh wave amplitude directivity is a complicated procedure [Haskell 1990] and proved to be too difficult in the far field without the aid of data from well-situated seismometers. Thus instead, we examined the role of seismic directivity, as determined by the faulting mechanism (normal, reverse, and strike-slip) and fault orientation, with respect to the wells, on the occurrence of tele-seismic induced well oscillations. We calculated the angle between the fault orientation and the great circle initial bearing from the epicenter to the South Florida well field, which we termed Delta. We found that for each faulting type, oscillatory events correlate well with specific Delta angles. For strike-slip events of sufficient SED, a strong correlation was found with events pointed away, 180°>Delta>90°, from the initial direction on the great circle path back to South Florida. For reverse faulting events, good correlation was found between oscillatory events and earthquakes oriented at Delta angles of 45° and 135°. There were not enough normal faulting events in our dataset to draw conclusions for this fault type. Our results indicate that oscillatory response to large tele-seismic waves depends not only on the magnitude and distance to the event, but also on the faulting type and fault orientation to the far field well.
Production of Staphylococcal Enterotoxins D and R in Milk and Meat Juice by Staphylococcus aureus Strains.

PubMed

Schubert, Justyna; Podkowik, Magdalena; Bystroń, Jarosław; Bania, Jacek

2017-04-01

Seventeen Staphylococcus aureus strains were tested for production of staphylococcal enterotoxin D (SED) and staphylococcal enterotoxin R (SER) in milk and meat juice. SED was secreted in milk by 12 S. aureus strains at 6-54 ng/mL at 24 h and 9-98 ng/mL at 48 h. Another five strains secreted SED at 0.9-1.9 μg/mL at 24 h and at 1.2-2.4 μg/mL at 48 h. Strains producing high levels of SED in milk secreted 77-666 μg/mL of SED in meat juice at 24 h and 132-1225 μg/mL at 48 h. Strains producing lower amounts of SED in milk secreted 228-1109 ng/mL of SED at 24 h and 377-1782 ng/mL at 48 h in meat juice. Tested S. aureus strains produced SER in milk at 33-183 ng/mL at 24 h and 41-832 ng/mL at 48 h. Fourteen strains produced more SER in meat juice than in milk (17- to 232-fold and 15- to 269-fold more at 24 and 48 h, respectively). Three S. aureus strains secreted less than 74 ng/mL of SER in meat juice. Expression pattern of known enterotoxin regulators, that is, agrA, sarA, hld, rot, and sigB, was similar in selected strong and weak SED producers grown in both food matrices and could not explain differences in enterotoxin protein level. This suggests that enterotoxin regulation is more complex than previously thought. We demonstrated that in a number of tested S. aureus strains, production of SED and SER was significantly decreased in milk when compared with meat juice, supporting previous reports. However, certain strains secreted high amounts of SED and SER, irrespective of environment, likely contributing to higher food safety risk.
A Profile of Secondary SED Classrooms in Virginia: Curriculum Development and Instructional Procedures.

ERIC Educational Resources Information Center

Graham, Marilyn Troth

A survey of curriculum and instructional practices in high school classrooms (N=151) in 82 school districts serving seriously emotionally disturbed (SED) and emotionally disturbed/learning disabled students in Virginia was conducted for the purpose of identifying the roles, responsibilities, and teaching skills for which SED teachers need to be…
The effect of chronic treadmill exercise and acetaminophen on collagen and cross-linking in rat skeletal muscle and heart.

PubMed

Carroll, Chad C; Martineau, Karl; Arthur, Kathryn A; Huynh, Richard T; Volper, Brent D; Broderick, Tom L

2015-02-15

The purpose of this study was to determine whether exercise and/or acetaminophen (APAP) alter collagen and cross-linking in the rat gastrocnemius muscle, soleus muscle, and heart. Male Wistar rats (n = 50; 8 wk old) were divided into placebo (PLA) or APAP groups and sedentary (SED) or exercised (RUN) groups. APAP (200 mg/kg) was administered daily by oral gavage. Exercised groups ran on a treadmill 5 days/wk for 8 wk with progression to 60 min/day, 20 m/min, and 8° incline. Tissues were assayed for collagen (hydroxyproline) and hydroxylyslpyridinoline (HP) and lysylpyridinoline (LP) cross-links by HPLC. Collagen content (μg/mg dry weight) was greater in both the gastrocnemius (SED-PLA: 114 ± 16 vs. 244 ± 32; P < 0.001) and soleus (SED-PLA: 51 ± 7 vs. 99 ± 27; P = 0.005) of exercised animals. In contrast, collagen content was not significantly greater in exercised animals treated with APAP (SED-APAP: 113 ± 16 vs. 145 ± 21) and soleus (SED-APAP: 55 ± 8 vs. 57 ± 10). HP cross-linking (mmol/mol collagen) in the gastrocnemius (SED-PLA: 126 ± 28, RUN-PLA: 50 ± 7, SED-APAP: 41 ± 7, and 30 ± 4) and soleus muscles (SED-PLA: 547 ± 107, RUN-PLA: 318 ± 92, SED-APAP: 247 ± 64, and 120 ± 17) was lower in exercised rats compared with sedentary rats (P < 0.05). Cross-linking was further reduced in animals treated with APAP (P < 0.05). Neither heart collagen nor cross-linking was influenced by exercise or APAP (P > 0.05). Our findings suggest that exercise and APAP have tissue-specific effects on muscle collagen. Given the widespread use of APAP as an analgesic and antipyretic, further work in humans is warranted. Copyright © 2015 the American Physiological Society.
Postprandial metabolism in resistance-trained versus sedentary males.

PubMed

Thyfault, John P; Richmond, Scott R; Carper, Michael J; Potteiger, Jeffrey A; Hulver, Matthew W

2004-04-01

This investigation examined if postprandial metabolism differed between resistance-trained [(RT), N = 12] and sedentary [(SED), N = 12] males. A secondary objective was to determine whether different resistance-training programs [bodybuilding (BB), N = 8 and power/weight-lifting (PL), N = 8] resulted in disparate effects on postprandial energy metabolism. Moderate fat [(MF), 37% carbohydrate, 18% protein, and 45% fat] and high carbohydrate [(HC), 79% carbohydrate, 20% protein, and 1% fat] meals were randomly administered, and postprandial metabolism was measured for 240 min. Carbohydrate oxidation, fat oxidation, diet-induced thermogenesis (DIT), and glucose and insulin areas under the curve (AUC) were calculated. Fat oxidization/lean body mass (LBM) was significantly greater in SED after the HC (RT, 0.27 +/- 0.02 g vs SED, 0.33 +/- 0.02 g, P = 0.017) and MF (RT, 0.34 +/- 0.02 g vs SED, 0.39 +/- 0.02 g, P = 0.036) meals. Carbohydrate oxidation/LBM was significantly greater in RT after the HC meal (RT, 0.87 +/- 0.03 g vs SED, 0.74 +/- 0.04 g, P = 0.017) only. DIT and DIT/LBM were significantly greater in RT compared with SED after the HC meal (DIT: RT, 351 +/- 21 kJ vs SED, 231 +/- 23 kJ, P = 0.001; DIT/LBM: RT, 5.25 +/- 0.028 kJ vs SED, 3.92 +/- 0.37 kJ, P = 0.009). The AUC for both glucose and insulin were significantly greater in SED compared with RT in response to the HC meal but not the MF meal. There were no differences in the BB and PL groups for any measured variables in response to either the HC or MF meals. These data indicate that postprandial metabolism is different between resistance-trained and sedentary males but that no such differences exist with different resistance training styles.

Correlates of Total Sedentary Time and Screen Time in 9-11 Year-Old Children around the World: The International Study of Childhood Obesity, Lifestyle and the Environment.

PubMed

LeBlanc, Allana G; Katzmarzyk, Peter T; Barreira, Tiago V; Broyles, Stephanie T; Chaput, Jean-Philippe; Church, Timothy S; Fogelholm, Mikael; Harrington, Deirdre M; Hu, Gang; Kuriyan, Rebecca; Kurpad, Anura; Lambert, Estelle V; Maher, Carol; Maia, José; Matsudo, Victor; Olds, Timothy; Onywera, Vincent; Sarmiento, Olga L; Standage, Martyn; Tudor-Locke, Catrine; Zhao, Pei; Tremblay, Mark S

2015-01-01

Previously, studies examining correlates of sedentary behavior have been limited by small sample size, restricted geographic area, and little socio-cultural variability. Further, few studies have examined correlates of total sedentary time (SED) and screen time (ST) in the same population. This study aimed to investigate correlates of SED and ST in children around the world. The sample included 5,844 children (45.6% boys, mean age = 10.4 years) from study sites in Australia, Brazil, Canada, China, Colombia, Finland, India, Kenya, Portugal, South Africa, the United Kingdom, and the United States. Child- and parent-reported behavioral, household, and neighborhood characteristics and directly measured anthropometric and accelerometer data were obtained. Twenty-one potential correlates of SED and ST were examined using multilevel models, adjusting for sex, age, and highest parental education, with school and study site as random effects. Variables that were moderately associated with SED and/or ST in univariate analyses (p<0.10) were included in the final models. Variables that remained significant in the final models (p<0.05) were considered correlates of SED and/or ST. Children averaged 8.6 hours of daily SED, and 54.2% of children failed to meet ST guidelines. In all study sites, boys reported higher ST, were less likely to meet ST guidelines, and had higher BMI z-scores than girls. In 9 of 12 sites, girls engaged in significantly more SED than boys. Common correlates of higher SED and ST included poor weight status, not meeting physical activity guidelines, and having a TV or a computer in the bedroom. In this global sample many common correlates of SED and ST were identified, some of which are easily modifiable (e.g., removing TV from the bedroom), and others that may require more intense behavioral interventions (e.g., increasing physical activity). Future work should incorporate these findings into the development of culturally meaningful public health messages.
Reproducible computational biology experiments with SED-ML - The Simulation Experiment Description Markup Language

PubMed Central

2011-01-01

Background The increasing use of computational simulation experiments to inform modern biological research creates new challenges to annotate, archive, share and reproduce such experiments. The recently published Minimum Information About a Simulation Experiment (MIASE) proposes a minimal set of information that should be provided to allow the reproduction of simulation experiments among users and software tools. Results In this article, we present the Simulation Experiment Description Markup Language (SED-ML). SED-ML encodes in a computer-readable exchange format the information required by MIASE to enable reproduction of simulation experiments. It has been developed as a community project and it is defined in a detailed technical specification and additionally provides an XML schema. The version of SED-ML described in this publication is Level 1 Version 1. It covers the description of the most frequent type of simulation experiments in the area, namely time course simulations. SED-ML documents specify which models to use in an experiment, modifications to apply on the models before using them, which simulation procedures to run on each model, what analysis results to output, and how the results should be presented. These descriptions are independent of the underlying model implementation. SED-ML is a software-independent format for encoding the description of simulation experiments; it is not specific to particular simulation tools. Here, we demonstrate that with the growing software support for SED-ML we can effectively exchange executable simulation descriptions. Conclusions With SED-ML, software can exchange simulation experiment descriptions, enabling the validation and reuse of simulation experiments in different tools. Authors of papers reporting simulation experiments can make their simulation protocols available for other scientists to reproduce the results. Because SED-ML is agnostic about exact modeling language(s) used, experiments covering models from different fields of research can be accurately described and combined. PMID:22172142
Propulsive Small Expendable Deployer System (ProSEDS)

NASA Technical Reports Server (NTRS)

1999-01-01

NASA's Propulsive Small Expendable Deployer System experiment (ProSEDS) will demonstrate the use of an electrodynamic tether, basically a long, thin wire, for propulsion. An electrodynamic tether uses the same principles as electric motors in toys, appliances and computer disk drives, and generators in automobiles and power plants. When electrical current is flowing through the tether, a magnetic field is produced that pushes against the magnetic field of the Earth. For ProSEDS, the current in the tether results by virtue of the voltage generated when the tether moves through the Earth's magnetic field at more than 17,000 mph. This approach can produce drag thrust generating useable power. Since electrodynamic tethers require no propellant, they could substantially reduce the weight of the spacecraft and provide a cost-effective method of reboosting spacecraft. The initial flight of ProSEDS is scheduled to fly aboard an Air Force Delta II rocket in the summer of 2002. In orbit, ProSEDS will deploy from a Delta II second stage. It will be a 3.1-mile (5 kilometer) long, ultrathin base-wire cornected with a 6.2-mile (10 kilometer) long nonconducting tether. This photograph shows Less Johnson, a scientist at MSFC inspecting the nonconducting part of a tether as it exits a deployer similar to the one to be used in the ProSEDS experiment. The ProSEDS experiment is managed by the Space Transportation Directorate at MSFC.
NEBULAR AND STELLAR DUST EXTINCTION ACROSS THE DISK OF EMISSION-LINE GALAXIES ON KILOPARSEC SCALES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hemmati, Shoubaneh; Mobasher, Bahram; Darvish, Behnam

We investigate the resolved kiloparsec-scale stellar and nebular dust distribution in eight star-forming galaxies at z ∼ 0.4 in the Great Observatories Origins Deep Survey fields. This is to get a better understanding of the effect of dust attenuation on measurements of physical properties and its variation with redshift. Constructing the observed spectral energy distributions (SEDs) per pixel, based on seven bands of photometric data from Hubble Space Telescope/Advanced Camera for Surveys and WFC3, we performed pixel-by-pixel SED fits to population synthesis models and estimated the small-scale distribution of stellar dust extinction. We use Hα/Hβ nebular emission line ratios from Keck/DEIMOS high-resolutionmore » spectra at each spatial resolution element to measure the amount of attenuation faced by ionized gas at different radii from the centers of galaxies. We find a good agreement between the integrated and median of resolved color excess measurements in our galaxies. The ratio of integrated nebular to stellar dust extinction is always greater than unity, but does not show any trend with stellar mass or star formation rate (SFR). We find that inclination plays an important role in the variation of the nebular to stellar excess ratio. The stellar color excess profiles are found to have higher values at the center compared to outer parts of the disk. However, for lower mass galaxies, a similar trend is not found for the nebular color excess. We find that the nebular color excess increases with stellar mass surface density. This explains the absence of radial trend in the nebular color excess in lower mass galaxies which lack a large radial variation of stellar mass surface density. Using standard conversions of SFR surface density to gas mass surface density, and the relation between dust mass surface density and color excess, we find no significant variation in the dust-to-gas ratio in regions with high gas mass surface densities over the scales probed in this study.« less
Changes of Dust Opacity with Density in the Orion A Molecular Cloud

NASA Astrophysics Data System (ADS)

Roy, Arabindo; Martin, Peter G.; Polychroni, Danae; Bontemps, Sylvain; Abergel, Alain; André, Philippe; Arzoumanian, Doris; Di Francesco, James; Hill, Tracey; Konyves, Vera; Nguyen-Luong, Quang; Pezzuto, Stefano; Schneider, Nicola; Testi, Leonardo; White, Glenn

2013-01-01

We have studied the opacity of dust grains at submillimeter wavelengths by estimating the optical depth from imaging at 160, 250, 350, and 500 μm from the Herschel Gould Belt Survey and comparing this to a column density obtained from the Two Micron All Sky Survey derived color excess E(J - K s). Our main goal was to investigate the spatial variations of the opacity due to "big" grains over a variety of environmental conditions and thereby quantify how emission properties of the dust change with column (and volume) density. The central and southern areas of the Orion A molecular cloud examined here, with N H ranging from 1.5 × 1021 cm-2 to 50 × 1021 cm-2, are well suited to this approach. We fit the multi-frequency Herschel spectral energy distributions (SEDs) of each pixel with a modified blackbody to obtain the temperature, T, and optical depth, τ1200, at a fiducial frequency of 1200 GHz (250 μm). Using a calibration of N H/E(J - Ks ) for the interstellar medium (ISM) we obtained the opacity (dust emission cross-section per H nucleon), σe(1200), for every pixel. From a value ~1 × 10-25 cm2 H-1 at the lowest column densities that is typical of the high-latitude diffuse ISM, σe(1200) increases as N 0.28 H over the range studied. This is suggestive of grain evolution. Integrating the SEDs over frequency, we also calculated the specific power P (emission power per H) for the big grains. In low column density regions where dust clouds are optically thin to the interstellar radiation field (ISRF), P is typically 3.7 × 10-31 W H-1, again close to that in the high-latitude diffuse ISM. However, we find evidence for a decrease of P in high column density regions, which would be a natural outcome of attenuation of the ISRF that heats the grains, and for localized increases for dust illuminated by nearby stars or embedded protostars.
Temporal and bi-directional associations between sleep duration and physical activity/sedentary time in children: An international comparison.

PubMed

Lin, Yingyi; Tremblay, Mark S; Katzmarzyk, Peter T; Fogelholm, Mikael; Hu, Gang; Lambert, Estelle V; Maher, Carol; Maia, Jose; Olds, Timothy; Sarmiento, Olga L; Standage, Martyn; Tudor-Locke, Catrine; Chaput, Jean-Philippe

2018-06-01

The purpose of this multinational and cross-sectional study was to investigate whether nighttime sleep duration was associated with physical activity (PA) and sedentary time (SED) the following day, whether daytime PA/SED were associated with sleep duration the subsequent night, and whether the associations were modified by sex and study sites. Data from 5779 children aged 9-11years were analyzed. A waist-worn Actigraph GT3X+ accelerometer was used to assess children's 24-h movement behaviours for 7days, i.e. sleep duration, total SED, light-intensity physical activity (LPA), and moderate- to vigorous-intensity physical activity (MVPA). Multilevel linear regression models were used to account for the repeated measures nested within participants (there were up to 7 sleep→PA/SED and PA/SED→sleep pairings per participant) and schools, and adjusted for covariates. To facilitate interpretation, all sleep and PA/SED variables were standardized. Results showed that the relationship between sleep and PA/SED is bi-directional in this international sample of children. Specifically, for each one standard deviation (SD) unit increase in sleep duration, SED the following day decreased by 0.04 SD units, while LPA and MVPA increased by 0.04 and 0.02 SD units, respectively. Sleep duration decreased by 0.02 SD units and increased by 0.04 SD units for each one SD unit increase in SED and MVPA, respectively. Sleep duration was not affected by changes in LPA. These associations differed across sex and study sites in both directions. However, since the observed effect sizes are subtle, public health initiatives should consider the clinical and practical relevance of these findings. Copyright © 2017 Elsevier Inc. All rights reserved.
Identification of Malassezia species isolated from Iranian seborrhoeic dermatitis patients.

PubMed

Hedayati, M T; Hajheydari, Z; Hajjar, F; Ehsani, A; Shokohi, T; Mohammadpour, R

2010-01-01

In recent years, the genus Malassezia has come to be considered important in the etiology of seborrhoeic dermatitis (SED). The aim of present study was identification of Malassezia species on the lesions of Iranian SED patients. 100 patients with SED were enrolled in the study. The patients were evaluated both clinically for the severity of SED and microscopically for the presence of the yeast Malassezia. Diagnosis of Malassezia was made after the yeast Malassezia was microscopically observed on skin scales stained with methylene blue. All samples were also cultivated on Leeming and Notman and Sabouraud's dextrose agar culture media. The agar plates were incubated at 32 degrees C for 2 weeks and evaluated for the existence of growth every day for one week. Identification of isolated yeast was based on morphological and physiological characteristics. From 100 patients with SED, 60% were female. The age range was 12-65 years with median 27.3 years. The highest prevalence of SED was seen in 20-29 years age group. 59% and 41% of patients had local and generalized lesions, respectively. 58% of patients showed lesion on scalp. Microscopic examination of skin scales was positive in 100% of SED lesions. 96% of patients showed more than 1-3 yeasts in each microscopic field whereas only 4% patients showed 1-3 yeasts in whole slide. Totally, 77% of the specimens yielded Malassezia in culture. Malassezia globosa was the most commonly isolated Malassezia species (55.8%). Malassezia globosa had also most frequencies on scalp and face lesions. Malassezia furfur had most frequency on trunk lesions. The results of our study showed high recovery rate of Malassezia species on lesions of patients with SED. So it might be playing a causative role in the etiology of this disease.
The effects of exercise on cocaine self-administration, food-maintained responding, and locomotor activity in female rats: importance of the temporal relationship between physical activity and initial drug exposure.

PubMed

Smith, Mark A; Witte, Maryam A

2012-12-01

Previous studies have reported that exercise decreases cocaine self-administration in rats with long-term access (8+ weeks) to activity wheels in the home cage. The purpose of this study was to (a) examine the importance of the temporal relationship between physical activity and initial drug exposure, (b) determine the effects of exercise on responding maintained by a nondrug reinforcer (i.e., food), and (c) investigate the effects of exercise on cocaine-induced increases in locomotor activity. To this end, female rats were obtained at weaning and divided into 4 groups: (a) EXE-SED rats were housed in exercise cages for 6 weeks and then transferred to sedentary cages after the first day of behavioral testing; (b) SED-EXE rats were housed in sedentary cages for 6 weeks and then transferred to exercise cages after the first day of behavioral testing; (c) SED-SED rats remained in sedentary cages for the duration of the study; and (d) EXE-EXE rats remained in exercise cages for the duration of the study. Relative to the sedentary group (SED-SED), exercise reduced cocaine self-administration in both groups with access to activity wheels after initial drug exposure (EXE-EXE, SED-EXE) but did not reduce cocaine self-administration in the group with access to activity wheels only before drug exposure (EXE-SED). Exercise also decreased the effects of cocaine on locomotor activity but did not reduce responding maintained by food. These data suggest that exercise may reduce cocaine use in drug-experienced individuals with no prior history of aerobic activity without decreasing other types of positively reinforced behaviors.
Active vs. sedentary lifestyle from weaning to adulthood and susceptibility to ozone in rats.

PubMed

Gordon, C J; Phillips, P M; Ledbetter, A; Snow, S J; Schladweiler, M C; Johnstone, A F M; Kodavanti, U P

2017-01-01

The prevalence of a sedentary (SED) life style combined with calorically rich diets has spurred the rise in childhood obesity, which, in turn, translates to adverse health effects in adulthood. Obesity and lack of active (ACT) lifestyle may increase susceptibility to air pollutants. We housed 22-day-old female Long-Evans rats in a cage without (SED) or with a running wheel (ACT). After 10 wk the rats ran 310 ± 16.3 km. Responses of SED and ACT rats to whole-body O 3 (0, 0.25, 0.5, or 1.0 ppm; 5 h/day for 2 days) was assessed. Glucose tolerance testing (GTT) was performed following the first day of O 3 ACT rats had less body fat and an improved glucose GTT. Ventilatory function (plethysmography) of SED and ACT groups was similarly impaired by O 3 Bronchoalveolar lavage fluid (BALF) was collected after the second O 3 exposure. SED and ACT rats were hyperglycemic following 1.0 ppm O 3 GTT was impaired by O 3 in both groups; however, ACT rats exhibited improved recovery to 0.25 and 1.0 ppm O 3 BALF cell neutrophils and total cells were similarly increased in ACT and SED groups exposed to 1.0 ppm O 3 O 3 -induced increase in eosinophils was exacerbated in SED rats. Chronic exercise from postweaning to adulthood improved some of the metabolic and pulmonary responses to O 3 (GTT and eosinophils) but several other parameters were unaffected. The reduction in O 3 -induced rise in BALF eosinophils in ACT rats suggests a possible link between a SED lifestyle and incidence of asthma-related symptoms from O 3 . Copyright © 2017 the American Physiological Society.
FDA-sunlamp recommended Maximum Timer Interval And Exposure Schedule: consensus ISO/CIE dose equivalence.

PubMed

Dowdy, John C; Czako, Eugene A; Stepp, Michael E; Schlitt, Steven C; Bender, Gregory R; Khan, Lateef U; Shinneman, Kenneth D; Karos, Manuel G; Shepherd, James G; Sayre, Robert M

2011-09-01

The authors compared calculations of sunlamp maximum exposure times following current USFDA Guidance Policy on the Maximum Timer Interval and Exposure Schedule, with USFDA/CDRH proposals revising these to equivalent erythemal exposures of ISO/CIE Standard Erythema Dose (SED). In 2003, [USFDA/CDRH proposed replacing their unique CDRH/Lytle] erythema action spectrum with the ISO/CIE erythema action spectrum and revising the sunlamp maximum exposure timer to 600 J m(-2) ISO/CIE effective dose, presented as being biologically equivalent. Preliminary analysis failed to confirm said equivalence, indicating instead ∼38% increased exposure when applying these proposed revisions. To confirm and refine this finding, a collaboration of tanning bed and UV lamp manufacturers compiled 89 UV spectra representing a broad sampling of U.S. indoor tanning equipment. USFDA maximum recommended exposure time (Te) per current sunlamp guidance and CIE erythemal effectiveness per ISO/CIE standard were calculated. The CIE effective dose delivered per Te averaged 456 J(CIE) m(-2) (SD = 0.17) or ∼4.5 SED. The authors found that CDRH's proposed 600 J(CIE) m(-2) recommended maximum sunlamp exposure exceeds current Te erythemal dose by ∼33%. The current USFDA 0.75 MED initial exposure was ∼0.9 SED, consistent with 1.0 SED initial dose in existing international sunlamp standards. As no sunlamps analyzed exceeded 5 SED, a revised maximum exposure of 500 J(CIE) m(-2) (∼80% of CDRH's proposal) should be compatible with existing tanning equipment. A tanning acclimatization schedule is proposed beginning at 1 SED thrice-weekly, increasing uniformly stepwise over 4 wk to a 5 SED maximum exposure in conjunction with a tan maintenance schedule of twice-weekly 5 SED sessions, as biologically equivalent to current USFDA sunlamp policy.
SED Modeling of 20 Massive Young Stellar Objects

NASA Astrophysics Data System (ADS)

Tanti, Kamal Kumar

In this paper, we present the spectral energy distributions (SEDs) modeling of twenty massive young stellar objects (MYSOs) and subsequently estimated different physical and structural/geometrical parameters for each of the twenty central YSO outflow candidates, along with their associated circumstellar disks and infalling envelopes. The SEDs for each of the MYSOs been reconstructed by using 2MASS, MSX, IRAS, IRAC & MIPS, SCUBA, WISE, SPIRE and IRAM data, with the help of a SED Fitting Tool, that uses a grid of 2D radiative transfer models. Using the detailed analysis of SEDs and subsequent estimation of physical and geometrical parameters for the central YSO sources along with its circumstellar disks and envelopes, the cumulative distribution of the stellar, disk and envelope parameters can be analyzed. This leads to a better understanding of massive star formation processes in their respective star forming regions in different molecular clouds.
Physical Education Increases Daily Moderate to Vigorous Physical Activity and Reduces Sedentary Time

ERIC Educational Resources Information Center

Mooses, Kerli; Pihu, Maret; Riso, Eva-Maria; Hannus, Aave; Kaasik, Priit; Kull, Merike

2017-01-01

Background: Physical activity (PA) is important to mental and physical health. Physical education (PE) lessons have the potential to increase daily moderate to vigorous PA (MVPA) and reduce sedentary time (SED). We measured MVPA and SED in primary school PE, determined the contribution of PE to daily MVPA and SED, and compared PA on days with and…
Theater of Operations Dental Work Load Estimation

DTIC Science & Technology

1984-05-01

such as clinical dental work, forensic dental identification, civic action ’programs, treatment of prisoners of war, dental laboratory services, medical...SED 193 0.3 115.8 0.2 9233 INHAL SED ANALGESIA 4085 7.0 3268.0 5.6 񕐲 ORAL SED 994 107 298.2’ 0.5 9235 HYPNOSIS 58 0.1 52.2 0.1 9610 THERAP MED
ProSEDS Telemetry System Utilization of GPS Position Data for Transmitter Cycling

NASA Technical Reports Server (NTRS)

Kennedy, Paul; Sims, Herb

2000-01-01

NASA Marshall Space Flight Center will launch the Propulsive Small Expendable Deployer System (ProSEDS) space experiment in late 2000. ProSEDS will demonstrate the use of an electrodynamic tether propulsion system and will utilize a conducting wire tether to generate limited spacecraft power. This paper will provide an overview of the ProSEDS mission and will discuss the design, development and test of the spacecraft telemetry system which utilizes a custom designed GPS subsystem to determine spacecraft position relative to ground station location and to control transmitter on/off cycling based on spacecraft state vector and ground station visibility.
Extending Iris: The VAO SED Analysis Tool

NASA Astrophysics Data System (ADS)

Laurino, O.; Busko, I.; Cresitello-Dittmar, M.; D'Abrusco, R.; Doe, S.; Evans, J.; Pevunova, O.

2013-10-01

Iris is a tool developed by the Virtual Astronomical Observatory (VAO) for building and analyzing Spectral Energy Distributions (SEDs). Iris was designed to be extensible, so that new components and models can be developed by third parties and then included at runtime. Iris can be extended in different ways: new file readers allow users to integrate data in custom formats into Iris SEDs; new models can be fitted to the data, in the form of template libraries for template fitting, data tables, and arbitrary Python functions. The interoperability-centered design of Iris and the Virtual Observatory standards and protocols can enable new science functionalities involving SED data.
Development of the Flight Tether for ProSEDS

NASA Technical Reports Server (NTRS)

Curtis, Leslie; Vaughn, Jason; Welzyn, Ken; Carroll, Joe; Brown, Norman S. (Technical Monitor)

2002-01-01

The Propulsive Small Expendable Deployer System (ProSEDS) space experiment will demonstrate the use of an electrodynamic tether propulsion system to generate thrust in space by decreasing the orbital altitude of a Delta 11 Expendable Launch Vehicle second stage. ProSEDS will use the flight-proven Small Expendable Deployer System to deploy a newly designed and developed tether which will provide tether generated drag thrust of approx. 0.4 N. The development and production of very long tethers with specific properties for performance and survivability will be required to enable future tether missions. The ProSEDS tether design and the development process may provide some lessons learned for these future missions. The ProSEDS system requirements drove the design of the tether to have three different sections of tether each serving a specialized purpose. The tether is a total of 15 kilometers long: 10 kilometers of a non-conductive Dyneema lead tether; 5 km of CCOR conductive coated wire; and 220 meters of insulated wire with a protective Kevlar overbraid. Production and joining of long tether lengths involved many development efforts. Extensive testing of tether materials including ground deployment of the full-length ProSEDS tether was conducted to validate the tether design and performance before flight.
Toluene decomposition performance and NOx by-product formation during a DBD-catalyst process.

PubMed

Guo, Yufang; Liao, Xiaobin; Fu, Mingli; Huang, Haibao; Ye, Daiqi

2015-02-01

Characteristics of toluene decomposition and formation of nitrogen oxide (NOx) by-products were investigated in a dielectric barrier discharge (DBD) reactor with/without catalyst at room temperature and atmospheric pressure. Four kinds of metal oxides, i.e., manganese oxide (MnOx), iron oxide (FeOx), cobalt oxide (CoOx) and copper oxide (CuO), supported on Al2O3/nickel foam, were used as catalysts. It was found that introducing catalysts could improve toluene removal efficiency, promote decomposition of by-product ozone and enhance CO2 selectivity. In addition, NOx was suppressed with the decrease of specific energy density (SED) and the increase of humidity, gas flow rate and toluene concentration, or catalyst introduction. Among the four kinds of catalysts, the CuO catalyst showed the best performance in NOx suppression. The MnOx catalyst exhibited the lowest concentration of O3 and highest CO2 selectivity but the highest concentration of NOx. A possible pathway for NOx production in DBD was discussed. The contributions of oxygen active species and hydroxyl radicals are dominant in NOx suppression. Copyright © 2014. Published by Elsevier B.V.
Stress shielding and fatigue limits of poly-ether-ether-ketone dental implants.

PubMed

Lee, Woo-Taek; Koak, Jai-Young; Lim, Young-Jun; Kim, Seong-Kyun; Kwon, Ho-Beom; Kim, Myung-Joo

2012-05-01

The poly-ether-ether-ketone (PEEK) polymer is of great interest as an alternative to titanium in orthopedics because of its biocompatibility and low elastic modulus. This study evaluated the fatigue limits of PEEK and the effects of the low elastic modulus PEEK in relation to existing dental implants. Compressive loading tests were performed with glass fiber-reinforced PEEK (GFR-PEEK), carbon fiber-reinforced PEEK (CFR-PEEK), and titanium rods. Among these tests, GFR-PEEK fatigue tests were performed according to ISO 14801. For the finite element analysis, three-dimensional models of dental implants and bone were constructed. The implants in the test groups were coated with a 0.5-mm thick and 5-mm long PEEK layer on the upper intrabony area. The strain energy densities (SED) were calculated, and the bone resorption was predicted. The fatigue limits of GFR-PEEK were 310 N and were higher than the static compressive strength of GFR-PEEK. The bone around PEEK-coated implants showed higher levels of SED than the bone in direct contact with the implants, and the wider diameter and stiffer implants showed lower levels of SED. The compressive strength of the GFR-PEEK and CFR-PEEK implants ranged within the bite force of the anterior and posterior dentitions, respectively, and the PEEK implants showed adequate fatigue limits for replacing the anterior teeth. Dental implants with PEEK coatings and PEEK implants may reduce stress shielding effects. Dental implant application of PEEK polymer-fatigue limit and stress shielding. Copyright © 2012 Wiley Periodicals, Inc.
X-ray-bright optically faint active galactic nuclei in the Subaru Hyper Suprime-Cam wide survey

NASA Astrophysics Data System (ADS)

Terashima, Yuichi; Suganuma, Makoto; Akiyama, Masayuki; Greene, Jenny E.; Kawaguchi, Toshihiro; Iwasawa, Kazushi; Nagao, Tohru; Noda, Hirofumi; Toba, Yoshiki; Ueda, Yoshihiro; Yamashita, Takuji

2018-01-01

We construct a sample of X-ray-bright optically faint active galactic nuclei by combining Subaru Hyper Suprime-Cam, XMM-Newton, and infrared source catalogs. Fifty-three X-ray sources satisfying i-band magnitude fainter than 23.5 mag and X-ray counts with the EPIC-PN detector larger than 70 are selected from 9.1 deg2, and their spectral energy distributions (SEDs) and X-ray spectra are analyzed. Forty-four objects with an X-ray to i-band flux ratio FX/Fi > 10 are classified as extreme X-ray-to-optical flux sources. Spectral energy distributions of 48 among 53 are represented by templates of type 2 AGNs or star-forming galaxies and show the optical signature of stellar emission from host galaxies in the source rest frame. Infrared/optical SEDs indicate a significant contribution of emission from dust to the infrared fluxes, and that the central AGN is dust obscured. The photometric redshifts determined from the SEDs are in the range of 0.6-2.5. The X-ray spectra are fitted by an absorbed power-law model, and the intrinsic absorption column densities are modest (best-fit log NH = 20.5-23.5 cm-2 in most cases). The absorption-corrected X-ray luminosities are in the range of 6 × 1042-2 × 1045 erg s-1. Twenty objects are classified as type 2 quasars based on X-ray luminsosity and NH. The optical faintness is explained by a combination of redshifts (mostly z > 1.0), strong dust extinction, and in part a large ratio of dust/gas.
Exercise during energy restriction mitigates bone loss but not alterations in estrogen status or metabolic hormones.

PubMed

Metzger, C E; Baek, K; Swift, S N; De Souza, M J; Bloomfield, S A

2016-09-01

Energy restriction causes bone loss, increasing stress fracture risk. The impact of exercise during energy restriction on bone and endocrine factors is examined. Exercise with energy restriction did not influence endocrine factors, but did mitigate some bone loss seen with energy restriction in sedentary rats. Chronic dietary energy restriction (ER) leads to bone loss and increased fracture risk. Strictly controlled trials of long-term ER with and without vigorous exercise are required to determine whether exercise loading can counterbalance ER-induced bone loss. The aim of this current project is to elucidate the impact of exercise and ER on bone mass, estrogen status, and metabolic hormones. Twenty-four virgin female Sprague-Dawley rats (n = 8/group) were divided into three groups-ad libitum fed + exercise (Adlib + EX), 40 % energy restricted + exercise (ER + EX), and 40 % energy restricted + sedentary (ER + SED). Energy availability between ER groups was equal. Treadmill running was performed 4 days/week at 70 % VO2max for 12 weeks. Fat and lean mass and areal bone mineral density (aBMD) were lower after 12 weeks (p < 0.05) for ER + EX vs Adlib + EX, but ER + EX aBMD was higher than ER + SED (p < 0.0001). Serum leptin and a urinary estrogen metabolite, estrone-1-glucuronide (E1G), were lower at week 12 (p = 0.0002) with ER, with no impact of exercise. Serum insulin-like growth factor I (IGF-I) declined (p = 0.02) from baseline to week 12 in both ER groups. ER + EX exhibited higher cortical volumetric bone mineral density (vBMD) at the midshaft tibia (p = 0.006) vs ER + SED. Exercise during ER mitigated some, but not all, of the bone loss observed in sedentary ER rats, but had little impact on changes in urinary E1G and serum IGF-I and leptin. These data highlight the importance of both adequate energy intake and the mechanical loading of exercise in maintaining bone mass.

Probing M Dwarf Model-Data Discrepancies via Precise, Empirical Characterization of a Long-Period F+M Binary

NASA Astrophysics Data System (ADS)

Stevens, Daniel; Gaudi, Scott; Beatty, Thomas; Siverd, Robert

2018-05-01

Double-lined eclipsing binaries (EBs) have been the gold standard for direct, precise (less than a few percent), and accurate measurements of stellar masses and radii. However, with the availability of Gaia parallaxes and nearly complete spectral energy distributions (SEDs) of millions of stars, it will soon be possible to make such measurements for the much larger number of single-lined EBs such as high mass-ratio systems and transiting planets, both of which are routinely found by transit surveys. Combining high-precision eclipse photometry and radial velocity (RV) observations of the primary star enables measurements of the primary star's density, the ratio of stellar radii, and a combination of the stars' masses. Broad-band photometry from the ultraviolet to the infrared plus a Gaia parallax and an effective temperature of the primary from either the SED or high-resolution spectra, allow one to measure the radius (and mass via the density) of the primary. The radius and mass of the secondary can then be determined in the usual way with the radius ratio and RVs, and the companion's effective temperature can be determined from a secondary eclipse measurement and the primary star's effective temperature. For single-lined EBs, the precision of ingress/egress duration measurements dominates the error budget of the masses and companion radius. We propose to observe one primary and secondary eclipse of the F+M binary TYC 4223-1012-1, an M dwarf on a 16.5-day orbit around an F dwarf. Ground-based data poorly constrain TYC 4223-1012-1's masses due to the near-impossibility of observing the full 10-hr eclipse from the ground. By combining extant RV and SED data with the Spitzer data, we expect to measure the mass, radius, and effective temperature of the M dwarf to a few percent. This is comparable to the precision of the best-characterized literature M dwarfs, but at an orbital period far beyond the majority of such systems, where tidal effects should be negligible.
Propulsive Small Expendable Deployer System (ProSEDS)

NASA Technical Reports Server (NTRS)

Curtis, Leslie; Johnson, Les; Brown, Norman S. (Technical Monitor)

2002-01-01

The Propulsive Small Expendable Deployer System (ProSEDS) space experiment will demonstrate the use of an electrodynamic tether propulsion system to generate thrust in space by decreasing the orbital altitude of a Delta 11 Expendable Launch Vehicle second stage. ProSEDS, which is planned on an Air Force GPS Satellite replacement mission in June 2002, will use the flight proven Small Expendable Deployer System (SEDS) to deploy a tether (5 km bare wire plus 10 km non-conducting Dyneema) from a Delta 11 second stage to achieve approx. 0.4N drag thrust. ProSEDS will utilize the tether-generated current to provide limited spacecraft power. The ProSEDS instrumentation includes Langmuir probes and Differential Ion Flux Probes, which will determine the characteristics of the ambient ionospheric plasma. Two Global Positioning System (GPS) receivers will be used (one on the Delta and one on the endmass) to help determine tether dynamics and to limit transmitter operations to occasions when the spacecraft is over selected ground stations. The flight experiment is a precursor to the more ambitious electrodynamic tether upper stage demonstration mission, which will be capable of orbit raising, lowering and inclination changes-all using electrodynamic thrust. An immediate application of ProSEDS technology is for the removal of spent satellites for orbital debris mitigation. In addition to the use of this technology to provide orbit transfer and debris mitigation it may also be an attractive option for future missions to Jupiter and any other planetary body with a magnetosphere.
Propulsive Small Expendable Deployer System (ProSEDS)

NASA Technical Reports Server (NTRS)

Ballance, Judy; Johnson, Les; Rogacki, John R. (Technical Monitor)

2000-01-01

The Propulsive Small Expendable Deployer System (ProSEDS) space experiment will demonstrate the use of an electrodynamic tether propulsion system to generate thrust in space by decreasing the orbital altitude of a Delta II Expendable Launch Vehicle (ELV) second stage. ProSEDS, which is planned to fly in 2001, will use the flight proven Small Expendable Deployer System (SEDS) to deploy a tether (5km bare wire plus 10 km spectra or dyneema) from a Delta II second stage to achieve approximately 0.4N drag thrust. ProSEDS will utilize the tether-generated current to provide limited spacecraft power. The ProSEDs instrumentation includes a Langmuir probe and Differential Ion Flux Probe, which will determine the characteristics of the ambient ionospheric plasma. Two Global Positioning System (GPS) receivers will be used (one on the Delta and one on the endmass) to help determine tether dynamics and to limit transmitter operations to occasions when the spacecraft is over selected ground stations, The flight experiment is a precursor to the more ambitious electrodynamic tether upper stage demonstration mission, which will be capable of orbit raising, lowering and inclination changes-all using electrodynamic thrust. An immediate application of ProSEDS technology is for the deorbit of spent satellites for orbital debris mitigation. In addition to the use of this technology to provide orbit transfer and debris mitigation it may also be an attractive option for future missions to Jupiter and any other planetary body with a magnetosphere.
VizieR Online Data Catalog: SSP in NIR. II. Synthesis models (Meneses-Goytia+, 2015)

NASA Astrophysics Data System (ADS)

Meneses-Goytia, S.; Peletier, R. F.; Trager, S. C.; Vazdekis, A.

2015-08-01

The present Single Stellar Populations (SSP) models are derived from my Ph.D.'s thesis and this paper. The following nomenclature is used throughout the paper and the website (http://smg.astro-research.net/ssp-models/the-models/) to describe the models, e.g. MarS models use the M08 isochrones (Mar) and the Salpeter (S) IMF. General information about the models is given in table1. For further information, please refer to the paper. Each set of models and their corresponding predictions are available in the website and VIZIER. The spectral energy distributions (SEDs) can be downloaded in a zip-file from those pages in ascii format . The spectral energy distributions (SEDs) can be downloaded in a zip-file from t hose pages in ascii format . The nomenclature of each SED is as follows: isochroneIMFsedXXXXHZX.XXXXXXXXXTgXX.XXXXXXXe+XX - where XXXX tells whether those models contain C-stars or no (COMBO or NOCS respectively) H is the spectral band in which normalization occurred Z_X.XXXXXXXXX is the metallicity in terms of Z Tg_XX.XXXXXXXe+XX is the age in years. Each set of models contains MarS - 96 SEDs GirS - 96 SEDs BaSS - 116 SEDs We have also included in the websites the Integrated colours and line-strength indices from all our models (MarS, GirS and BaSS). The SEDs were convolved to a velocity dispersion of 350km/s before calculating indices. (5 data files).
The Space Density of Luminous Dusty Star-forming Galaxies at z > 4: SCUBA-2 and LABOCA Imaging of Ultrared Galaxies from Herschel-ATLAS

NASA Astrophysics Data System (ADS)

Ivison, R. J.; Lewis, A. J. R.; Weiss, A.; Arumugam, V.; Simpson, J. M.; Holland, W. S.; Maddox, S.; Dunne, L.; Valiante, E.; van der Werf, P.; Omont, A.; Dannerbauer, H.; Smail, Ian; Bertoldi, F.; Bremer, M.; Bussmann, R. S.; Cai, Z.-Y.; Clements, D. L.; Cooray, A.; De Zotti, G.; Eales, S. A.; Fuller, C.; Gonzalez-Nuevo, J.; Ibar, E.; Negrello, M.; Oteo, I.; Pérez-Fournon, I.; Riechers, D.; Stevens, J. A.; Swinbank, A. M.; Wardlow, J.

2016-11-01

Until recently, only a handful of dusty, star-forming galaxies (DSFGs) were known at z > 4, most of them significantly amplified by gravitational lensing. Here, we have increased the number of such DSFGs substantially, selecting galaxies from the uniquely wide 250, 350, and 500 μm Herschel-ATLAS imaging survey on the basis of their extremely red far-infrared colors and faint 350 and 500 μm flux densities, based on which, they are expected to be largely unlensed, luminous, rare, and very distant. The addition of ground-based continuum photometry at longer wavelengths from the James Clerk Maxwell Telescope and the Atacama Pathfinder Experiment allows us to identify the dust peak in their spectral energy distributions (SEDs), with which we can better constrain their redshifts. We select the SED templates that are best able to determine photometric redshifts using a sample of 69 high-redshift, lensed DSFGs, then perform checks to assess the impact of the CMB on our technique, and to quantify the systematic uncertainty associated with our photometric redshifts, σ = 0.14 (1 + z), using a sample of 25 galaxies with spectroscopic redshifts, each consistent with our color selection. For Herschel-selected ultrared galaxies with typical colors of S 500/S 250 ˜ 2.2 and S 500/S 350 ˜ 1.3 and flux densities, S 500 ˜ 50 mJy, we determine a median redshift, {\\hat{z}}{phot}=3.66, an interquartile redshift range, 3.30-4.27, with a median rest-frame 8-1000 μm luminosity, {\\hat{L}}{IR}, of 1.3 × 1013 L ⊙. A third of the galaxies lie at z > 4, suggesting a space density, ρ z > 4, of ≈6 × 10-7 Mpc-3. Our sample contains the most luminous known star-forming galaxies, and the most overdense cluster of starbursting proto-ellipticals found to date.
Formation of curcumin nanoparticles via solution-enhanced dispersion by supercritical CO2

PubMed Central

Zhao, Zheng; Xie, Maobin; Li, Yi; Chen, Aizheng; Li, Gang; Zhang, Jing; Hu, Huawen; Wang, Xinyu; Li, Shipu

2015-01-01

In order to enhance the bioavailability of poorly water-soluble curcumin, solution-enhanced dispersion by supercritical carbon dioxide (CO2) (SEDS) was employed to prepare curcumin nanoparticles for the first time. A 24 full factorial experiment was designed to determine optimal processing parameters and their influence on the size of the curcumin nanoparticles. Particle size was demonstrated to increase with increased temperature or flow rate of the solution, or with decreased precipitation pressure, under processing conditions with different parameters considered. The single effect of the concentration of the solution on particle size was not significant. Curcumin nanoparticles with a spherical shape and the smallest mean particle size of 325 nm were obtained when the following optimal processing conditions were adopted: P =20 MPa, T =35°C, flow rate of solution =0.5 mL·min−1, concentration of solution =0.5%. Fourier transform infrared (FTIR) spectroscopy measurement revealed that the chemical composition of curcumin basically remained unchanged. Nevertheless, X-ray powder diffraction (XRPD) and thermal analysis indicated that the crystalline state of the original curcumin decreased after the SEDS process. The solubility and dissolution rate of the curcumin nanoparticles were found to be higher than that of the original curcumin powder (approximately 1.4 μg/mL vs 0.2 μg/mL in 180 minutes). This study revealed that supercritical CO2 technologies had a great potential in fabricating nanoparticles and improving the bioavailability of poorly water-soluble drugs. PMID:25995627
Formation of curcumin nanoparticles via solution-enhanced dispersion by supercritical CO2.

PubMed

Zhao, Zheng; Xie, Maobin; Li, Yi; Chen, Aizheng; Li, Gang; Zhang, Jing; Hu, Huawen; Wang, Xinyu; Li, Shipu

2015-01-01

In order to enhance the bioavailability of poorly water-soluble curcumin, solution-enhanced dispersion by supercritical carbon dioxide (CO2) (SEDS) was employed to prepare curcumin nanoparticles for the first time. A 2(4) full factorial experiment was designed to determine optimal processing parameters and their influence on the size of the curcumin nanoparticles. Particle size was demonstrated to increase with increased temperature or flow rate of the solution, or with decreased precipitation pressure, under processing conditions with different parameters considered. The single effect of the concentration of the solution on particle size was not significant. Curcumin nanoparticles with a spherical shape and the smallest mean particle size of 325 nm were obtained when the following optimal processing conditions were adopted: P = 20 MPa, T = 35°C, flow rate of solution = 0.5 mL·min(-1), concentration of solution = 0.5%. Fourier transform infrared (FTIR) spectroscopy measurement revealed that the chemical composition of curcumin basically remained unchanged. Nevertheless, X-ray powder diffraction (XRPD) and thermal analysis indicated that the crystalline state of the original curcumin decreased after the SEDS process. The solubility and dissolution rate of the curcumin nanoparticles were found to be higher than that of the original curcumin powder (approximately 1.4 μg/mL vs 0.2 μg/mL in 180 minutes). This study revealed that supercritical CO2 technologies had a great potential in fabricating nanoparticles and improving the bioavailability of poorly water-soluble drugs.
Correlates of Total Sedentary Time and Screen Time in 9–11 Year-Old Children around the World: The International Study of Childhood Obesity, Lifestyle and the Environment

PubMed Central

LeBlanc, Allana G.; Katzmarzyk, Peter T.; Barreira, Tiago V.; Broyles, Stephanie T.; Chaput, Jean-Philippe; Church, Timothy S.; Fogelholm, Mikael; Harrington, Deirdre M.; Hu, Gang; Kuriyan, Rebecca; Kurpad, Anura; Lambert, Estelle V.; Maher, Carol; Maia, José; Matsudo, Victor; Olds, Timothy; Onywera, Vincent; Sarmiento, Olga L.; Standage, Martyn; Tudor-Locke, Catrine; Zhao, Pei; Tremblay, Mark S.

2015-01-01

Purpose Previously, studies examining correlates of sedentary behavior have been limited by small sample size, restricted geographic area, and little socio-cultural variability. Further, few studies have examined correlates of total sedentary time (SED) and screen time (ST) in the same population. This study aimed to investigate correlates of SED and ST in children around the world. Methods The sample included 5,844 children (45.6% boys, mean age = 10.4 years) from study sites in Australia, Brazil, Canada, China, Colombia, Finland, India, Kenya, Portugal, South Africa, the United Kingdom, and the United States. Child- and parent-reported behavioral, household, and neighborhood characteristics and directly measured anthropometric and accelerometer data were obtained. Twenty-one potential correlates of SED and ST were examined using multilevel models, adjusting for sex, age, and highest parental education, with school and study site as random effects. Variables that were moderately associated with SED and/or ST in univariate analyses (p<0.10) were included in the final models. Variables that remained significant in the final models (p<0.05) were considered correlates of SED and/or ST. Results Children averaged 8.6 hours of daily SED, and 54.2% of children failed to meet ST guidelines. In all study sites, boys reported higher ST, were less likely to meet ST guidelines, and had higher BMI z-scores than girls. In 9 of 12 sites, girls engaged in significantly more SED than boys. Common correlates of higher SED and ST included poor weight status, not meeting physical activity guidelines, and having a TV or a computer in the bedroom. Conclusions In this global sample many common correlates of SED and ST were identified, some of which are easily modifiable (e.g., removing TV from the bedroom), and others that may require more intense behavioral interventions (e.g., increasing physical activity). Future work should incorporate these findings into the development of culturally meaningful public health messages. PMID:26068231
Star-forming Galaxies as AGN Imposters? A Theoretical Investigation of the Mid-infrared Colors of AGNs and Extreme Starbursts

NASA Astrophysics Data System (ADS)

Satyapal, Shobita; Abel, Nicholas P.; Secrest, Nathan J.

2018-05-01

We conduct for the first time a theoretical investigation of the mid-infrared spectral energy distribution (SED) produced by dust heated by an active galactic nucleus (AGN) and an extreme starburst. These models employ an integrated modeling approach using photoionization and stellar population synthesis models in which both the line and emergent continuum is predicted from gas exposed to the ionizing radiation from a young starburst and an AGN. In this work, we focus on the infrared colors from the Wide-field Infrared Survey Explorer, predicting the dependence of the colors on the input radiation field, the interstellar medium conditions, the obscuring column, and the metallicity. We find that an extreme starburst can mimic an AGN in two band mid-infrared color cuts employed in the literature. However, the three-band color cuts employed in the literature require starbursts with extremely high ionization parameters or gas densities. We show that the extreme mid-infrared colors seen in some blue compact dwarf galaxies are not due to metallicity but rather a combination of high ionization parameters and high column densities. Based on our theoretical calculations, we present a theoretical mid-infrared color cut that will exclude even the most extreme starburst that we have modeled in this work. The theoretical AGN demarcation region presented here can be used to identify elusive AGN candidates for future follow-up studies with the James Webb Space Telescope. The full suite of simulated SEDs are available online.
Properties and Expected Number Counts of Active Galactic Nuclei and Their Hosts in the Far-infrared

NASA Astrophysics Data System (ADS)

Draper, A. R.; Ballantyne, D. R.

2011-03-01

Telescopes like Herschel and the Atacama Large Millimeter/submillimeter Array (ALMA) are creating new opportunities to study sources in the far-infrared (FIR), a wavelength region dominated by cold dust emission. Probing cold dust in active galaxies allows for study of the star formation history of active galactic nucleus (AGN) hosts. The FIR is also an important spectral region for observing AGNs which are heavily enshrouded by dust, such as Compton thick (CT) AGNs. By using information from deep X-ray surveys and cosmic X-ray background synthesis models, we compute Cloudy photoionization simulations which are used to predict the spectral energy distribution (SED) of AGNs in the FIR. Expected differential number counts of AGNs and their host galaxies are calculated in the Herschel bands. The expected contribution of AGNs and their hosts to the cosmic infrared background (CIRB) and the infrared luminosity density are also computed. Multiple star formation scenarios are investigated using a modified blackbody star formation SED. It is found that FIR observations at ~500 μm are an excellent tool in determining the star formation history of AGN hosts. Additionally, the AGN contribution to the CIRB can be used to determine whether star formation in AGN hosts evolves differently than in normal galaxies. The contribution of CT AGNs to the bright end differential number counts and to the bright source infrared luminosity density is a good test of AGN evolution models where quasars are triggered by major mergers.
Identifying and Evaluating Options for Improving Sediment Management and Fish Passage at Hydropower Dams in the Lower Mekong River Basin

NASA Astrophysics Data System (ADS)

Wild, T. B.; Reed, P. M.; Loucks, D. P.

2015-12-01

The Mekong River basin in Southeast Asia is undergoing intensive and pervasive hydropower development to satisfy demand for increased energy and income to support its growing population of 60 million people. Just 20 years ago this river flowed freely. Today some 30 large dams exist in the basin, and over 100 more are being planned for construction. These dams will alter the river's natural water, sediment and nutrient flows, thereby impacting river morphology and ecosystems, and will fragment fish migration pathways. In doing so, they will degrade one of the world's most valuable and productive freshwater fish habitats. For those dams that have not yet been constructed, there still exist opportunities to modify their siting, design and operation (SDO) to potentially achieve a more balanced set of tradeoffs among hydropower production, sediment/nutrient passage and fish passage. We introduce examples of such alternative SDO opportunities for Sambor Dam in Cambodia, planned to be constructed on the main stem of the Mekong River. To evaluate the performance of such alternatives, we developed a Python-based simulation tool called PySedSim. PySedSim is a daily time step mass balance model that identifies the relative tradeoffs among hydropower production, and flow and sediment regime alteration, associated with reservoir sediment management techniques such as flushing, sluicing, bypassing, density current venting and dredging. To date, there has been a very limited acknowledgement or evaluation of the significant uncertainties that impact the evaluation of SDO alternatives. This research is formalizing a model diagnostic assessment of the key assumptions and parametric uncertainties that strongly influence PySedSim SDO evaluations. Using stochastic hydrology and sediment load data, our diagnostic assessment evaluates and compares several Sambor Dam alternatives using several performance measures related to energy production, sediment trapping and regime alteration, and fish passage. We show that performance of the alternatives can be highly variable, and conduct a simultaneous multi-parameter factor screening sensitivity analysis to identify the subset of PySedSim model parameters that contribute most significantly to performance uncertainties in attempts to identify the more robust options.
Effects of high-intensity intermittent training on carnitine palmitoyl transferase activity in the gastrocnemius muscle of rats

PubMed Central

Carnevali, L.C.; Eder, R.; Lira, F.S.; Lima, W.P.; Gonçalves, D.C.; Zanchi, N.E.; Nicastro, H.; Lavoie, J.M.; Seelaender, M.C.L.

2012-01-01

We examined the capacity of high-intensity intermittent training (HI-IT) to facilitate the delivery of lipids to enzymes responsible for oxidation, a task performed by the carnitine palmitoyl transferase (CPT) system in the rat gastrocnemius muscle. Male adult Wistar rats (160-250 g) were randomly distributed into 3 groups: sedentary (Sed, N = 5), HI-IT (N = 10), and moderate-intensity continuous training (MI-CT, N = 10). The trained groups were exercised for 8 weeks with a 10% (HI-IT) and a 5% (MI-CT) overload. The HI-IT group presented 11.8% decreased weight gain compared to the Sed group. The maximal activities of CPT-I, CPT-II, and citrate synthase were all increased in the HI-IT group compared to the Sed group (P < 0.01), as also was gene expression, measured by RT-PCR, of fatty acid binding protein (FABP; P < 0.01) and lipoprotein lipase (LPL; P < 0.05). Lactate dehydrogenase also presented a higher maximal activity (nmol·min−1·mg protein−1) in HI-IT (around 83%). We suggest that 8 weeks of HI-IT enhance mitochondrial lipid transport capacity thus facilitating the oxidation process in the gastrocnemius muscle. This adaptation may also be associated with the decrease in weight gain observed in the animals and was concomitant to a higher gene expression of both FABP and LPL in HI-IT, suggesting that intermittent exercise is a “time-efficient” strategy inducing metabolic adaptation. PMID:22735180
The Planck Dusty Gravitationally Enhanced subMillimeter Sources (GEMS)

NASA Astrophysics Data System (ADS)

Frye, Brenda

2015-10-01

The brightest, strongly lensed high-redshift galaxies are veritable gems to study intense star formation in the early Universe. How do the high and irregular clumpy stellar and gas mass surface densities, strong radiation fields, and high turbulence regulate the rapid growth of these galaxies? We will use HST/WFC3 to investigate the stellar component of 6 of the brightest high-redshift sub-millimeter galaxies on the sky, which were recently discovered with the Planck all-sky survey. All are giant arcs or partial Einstein rings with angular sizes up to 17 in shallow CFHT K-band or Spitzer/IRAC imaging. FIR luminosities are 10^13-14 L_sun, with dust SEDs strongly dominated by intense star formation near the maximum possible rates (maximal starbursts). All have spectroscopic redshifts z=2.2-3.6 and magnification factors >/=20. We already have multiwavelength data sets to characterize their gas and dust column densities and kinematics, and propose here to acquire deep, high-resolution rest-frame optical imaging to study the stellar populations and morphologies. With WFC3 imaging in F110W & F160W we will: (1) constrain the stellar morphologies, ages, and mass-to-light ratios (2) Identify clumps and measure their properties to test several clump formation scenarios(3) Enhance our on-going lens modeling through the most accurate positions, morphologies and colorsOnly the brightest of the arc clumps are visible from the ground in the NIR. To register the flux along the full extent of the arcs, and importantly to probe individual star forming regions of the size of 30 Dor at z 2-3 in the brightest high-z sub-mm galaxies requires HST.
Imaging Magnetospheric Perturbations of the Ionosphere/Plasmasphere System from the Ground and Space

NASA Astrophysics Data System (ADS)

Foster, J. C.

2004-05-01

The thermal plasmas of the inner magnetosphere and ionosphere move across the magnetic field under the influence of electric fields. Irrespective of their source, these electric fields extend along magnetic field lines coupling the motion of thermal plasmas in the various altitude regimes. Modern remote-sensing techniques based both on the ground and in space are providing a new view of the large and meso-scale characteristics and dynamics of the plasmas of the extended ionosphere and their importance in understanding processes and effects observed throughout the coupled spheres of Earth's upper atmosphere. During strong geomagnetic storms, disturbance electric fields uplift and redistribute the thermal plasma of the low-latitude ionosphere and inner magnetosphere, producing a pronounced poleward shift of the equatorial anomalies (EA) and enhancements of plasma concentration (total electric content, TEC) in the post-noon plasmasphere. Strong SAPS (subauroral polarization stream) electric fields erode the plasmasphere boundary layer in the region of the dusk-sector bulge, producing plasmaspheric drainage plumes which carry the high-altitude material towards the dayside magnetopause. The near-Earth footprint of these flux tubes constitutes the mid-latitude streams of storm-enhanced density (SED) which produce considerable space weather effects across the North American continent. We use ground-based GPS propagation data to produce two-dimensional maps and movies of the evolution of these TEC features as they progress from equatorial regions to the polar caps. DMSP satellite overflights provide in-situ density and plasma flow/electric field observations, while the array of incoherent scatter radars probe the altitude distribution and characteristics of these dynamic thermal plasma features. IMAGE EUV and FUV observations reveal the space-based view of spatial extent and temporal evolution of these phenomena.
Stochastic Energy Deployment System

DOE Office of Scientific and Technical Information (OSTI.GOV)

2011-11-30

SEDS is an economy-wide energy model of the U.S. The model captures dynamics between supply, demand, and pricing of the major energy types consumed and produced within the U.S. These dynamics are captured by including: the effects of macroeconomics; the resources and costs of primary energy types such as oil, natural gas, coal, and biomass; the conversion of primary fuels into energy products like petroleum products, electricity, biofuels, and hydrogen; and lastly the end- use consumption attributable to residential and commercial buildings, light and heavy transportation, and industry. Projections from SEDS extend to the year 2050 by one-year time stepsmore » and are generally projected at the national level. SEDS differs from other economy-wide energy models in that it explicitly accounts for uncertainty in technology, markets, and policy. SEDS has been specifically developed to avoid the computational burden, and sometimes fruitless labor, that comes from modeling significantly low-level details. Instead, SEDS focuses on the major drivers within the energy economy and evaluates the impact of uncertainty around those drivers.« less
SED Constraints on the Highest- z Blazar Jet: QSO J0906+6930

DOE Office of Scientific and Technical Information (OSTI.GOV)

An, Hongjun; Romani, Roger W.

Here, we report on Gemini, NuSTAR, and eight years of Fermi observations of the most distant blazar QSO J0906+6930 (z = 5.48). We construct a broadband spectral energy distribution (SED) and model the SED using a synchro-Compton model. The measurements yield a mass of ~4 × 10 9 M ⊙ for the black hole and a spectral break at ~4 keV in the combined fit of the new NuSTAR and archival Chandra data. The SED fitting constrains the bulk Doppler factor δ of the jet to 9 +2.5 –3 for QSO J0906+6930. Similar, but weaker, constraints on δ are derivedmore » from SED modeling of the three other claimed z > 5 blazars. Together, these extrapolate to ~620 similar sources, fully 20% of the optically bright, high-mass active galactic nuclei expected at 5 < z < 5.5. This has interesting implications for the early growth of massive black holes.« less
Immunohistochemical expression of basement membrane proteins of verrucous carcinoma of the oral mucosa.

PubMed

Arduino, Paolo G; Carrozzo, Marco; Pagano, Marco; Broccoletti, Roberto; Scully, Crispian; Gandolfo, Sergio

2010-06-01

Squamous cell carcinoma (SCC) of the oral cavity is an extremely invasive tumour of stratified squamous epithelium that spreads throughout degradation of the basement membrane (BM) and extra-cellular matrix. Oral verrucous carcinoma (VC) is a rare low-grade variant of oral SCC that penetrates into the subepithelial connective tissue. It also has a different clinical behaviour from classical oral SCC. We investigated the immunohistochemical expression of laminin, laminin-5, collagen IV and fibronectin in VC, severe epithelial dysplasia (SED) and SCC in order to analyse if the pattern of these molecules expression contributes to the differences in the biological behaviour of these diseases. The staining pattern of laminin was less intensive in SCC compared with SED and VC, and collagen IV expression was increased in VC compared with SED. Discontinuities of laminin, collagen IV and fibronectin were more evident in SED than in VC. This study indicates that VC has a biological behaviour different from SED or SCC, observable by immunohistochemistry in the BM zone.
SED Constraints on the Highest-z Blazar Jet: QSO J0906+6930

NASA Astrophysics Data System (ADS)

An, Hongjun; Romani, Roger W.

2018-04-01

We report on Gemini, NuSTAR, and eight years of Fermi observations of the most distant blazar QSO J0906+6930 (z = 5.48). We construct a broadband spectral energy distribution (SED) and model the SED using a synchro-Compton model. The measurements yield a mass of ∼4 × 109 M ⊙ for the black hole and a spectral break at ∼4 keV in the combined fit of the new NuSTAR and archival Chandra data. The SED fitting constrains the bulk Doppler factor δ of the jet to 9+2.5 ‑3 for QSO J0906+6930. Similar, but weaker, constraints on δ are derived from SED modeling of the three other claimed z > 5 blazars. Together, these extrapolate to ∼620 similar sources, fully 20% of the optically bright, high-mass active galactic nuclei expected at 5 < z < 5.5. This has interesting implications for the early growth of massive black holes.
SED Constraints on the Highest- z Blazar Jet: QSO J0906+6930

DOE PAGES

An, Hongjun; Romani, Roger W.

2018-03-29

Here, we report on Gemini, NuSTAR, and eight years of Fermi observations of the most distant blazar QSO J0906+6930 (z = 5.48). We construct a broadband spectral energy distribution (SED) and model the SED using a synchro-Compton model. The measurements yield a mass of ~4 × 10 9 M ⊙ for the black hole and a spectral break at ~4 keV in the combined fit of the new NuSTAR and archival Chandra data. The SED fitting constrains the bulk Doppler factor δ of the jet to 9 +2.5 –3 for QSO J0906+6930. Similar, but weaker, constraints on δ are derivedmore » from SED modeling of the three other claimed z > 5 blazars. Together, these extrapolate to ~620 similar sources, fully 20% of the optically bright, high-mass active galactic nuclei expected at 5 < z < 5.5. This has interesting implications for the early growth of massive black holes.« less
Phytase supplementation increases bone mineral density, lean body mass and voluntary physical activity in rats fed a low-zinc diet.

PubMed

Scrimgeour, Angus G; Marchitelli, Louis J; Whicker, Jered S; Song, Yang; Ho, Emily; Young, Andrew J

2010-07-01

Phytic acid forms insoluble complexes with nutritionally essential minerals, including zinc (Zn). Animal studies show that addition of microbial phytase (P) to low-Zn diets improves Zn status and bone strength. The present study determined the effects of phytase supplementation on bone mineral density (BMD), body composition and voluntary running activity of male rats fed a high phytic acid, low-Zn diet. In a factorial design, rats were assigned to ZnLO (5 mg/kg diet), ZnLO+P (ZnLO diet with 1500 U phytase/kg) or ZnAD (30 mg/kg diet) groups and were divided into voluntary exercise (EX) or sedentary (SED) groups, for 9 weeks. SED rats were significantly heavier from the second week, and no catch-up growth occurred in EX rats. Feed intakes were not different between groups throughout the study. ZnLO animals had decreased food efficiency ratios compared to both phytase-supplemented (ZnLO+P) and Zn-adequate (ZnAD) animals (P<.01 compared to ZnLO). The ZnLO+P and ZnAD rats ran 56-75 km more total distance than ZnLO rats (P<.05), with the ZnLO+P rats running more kilometers per week than the ZnLO rats by Week 6. In vivo DEXA analyses indicate that rats fed phytase-supplemented diets had higher lean body mass (LBM) than those fed ZnLO diets; and that rats fed the Zn-adequate diets had the highest LBM. Body fat (%) was significantly lower in EX rats and was both Zn- and phytase insensitive. Rats fed phytase-supplemented diets had higher bone mineral content (BMC), bone area (BA) and BMD than rats fed ZnLO diets; and in rats fed ZnAD diets these indices were the highest. The dietary effects on BMC, BA and BMD were independent of activity level. We conclude that consuming supplemental dietary phytase or dietary Zn additively enhances Zn status to increase BMD, LBM and voluntary physical activity in rats fed a low-Zn diet. While the findings confirm that bone health is vulnerable to disruption by moderate Zn deficiency in rats, this new data suggests that if dietary Zn is limiting, supplemental phytase may have beneficial effects on LBM and performance activity. (c) 2010 Elsevier Inc. All rights reserved.

Extending Supernova Spectral Templates for Next Generation Space Telescope Observations

NASA Astrophysics Data System (ADS)

Roberts-Pierel, Justin; Rodney, Steven A.; Steven Rodney

2018-01-01

Widely used empirical supernova (SN) Spectral Energy Distributions (SEDs) have not historically extended meaningfully into the ultraviolet (UV), or the infrared (IR). However, both are critical for current and future aspects of SN research including UV spectra as probes of poorly understood SN Ia physical properties, and expanding our view of the universe with high-redshift James Webb Space Telescope (JWST) IR observations. We therefore present a comprehensive set of SN SED templates that have been extended into the UV and IR, as well as an open-source software package written in Python that enables a user to generate their own extrapolated SEDs. We have taken a sampling of core-collapse (CC) and Type Ia SNe to get a time-dependent distribution of UV and IR colors (U-B,r’-[JHK]), and then generated color curves are used to extrapolate SEDs into the UV and IR. The SED extrapolation process is now easily duplicated using a user’s own data and parameters via our open-source Python package: SNSEDextend. This work develops the tools necessary to explore the JWST’s ability to discriminate between CC and Type Ia SNe, as well as provides a repository of SN SEDs that will be invaluable to future JWST and WFIRST SN studies.
Simulation Experiment Description Markup Language (SED-ML) Level 1 Version 3 (L1V3).

PubMed

Bergmann, Frank T; Cooper, Jonathan; König, Matthias; Moraru, Ion; Nickerson, David; Le Novère, Nicolas; Olivier, Brett G; Sahle, Sven; Smith, Lucian; Waltemath, Dagmar

2018-03-19

The creation of computational simulation experiments to inform modern biological research poses challenges to reproduce, annotate, archive, and share such experiments. Efforts such as SBML or CellML standardize the formal representation of computational models in various areas of biology. The Simulation Experiment Description Markup Language (SED-ML) describes what procedures the models are subjected to, and the details of those procedures. These standards, together with further COMBINE standards, describe models sufficiently well for the reproduction of simulation studies among users and software tools. The Simulation Experiment Description Markup Language (SED-ML) is an XML-based format that encodes, for a given simulation experiment, (i) which models to use; (ii) which modifications to apply to models before simulation; (iii) which simulation procedures to run on each model; (iv) how to post-process the data; and (v) how these results should be plotted and reported. SED-ML Level 1 Version 1 (L1V1) implemented support for the encoding of basic time course simulations. SED-ML L1V2 added support for more complex types of simulations, specifically repeated tasks and chained simulation procedures. SED-ML L1V3 extends L1V2 by means to describe which datasets and subsets thereof to use within a simulation experiment.
Pathfinder

NASA Image and Video Library

2001-07-01

This photograph shows two Marshall Space Flight Center (MSFC) engineers, Mark Vaccaro (left) and Ken Welzyn, testing electrodynamic tethers in the MSFC Tether Winding and Spark Testing Facility. For 4 years, MSFC and industry partners have been developing the Propulsive Small Expendable Deployer System experiment, called ProSEDS. ProSEDS will test electrodynamic tether propulsion technology. Electrodynamic tethers are long, thin wires that collect electrical current when passing through a magnetic field. The tether works as a thruster as a magnetic field exerts a force on a current-carrying wire. Since electrodynamic tethers require no propellant, they could substantially reduce the weight of the spacecraft and provide a cost-effective method of reboosting spacecraft. The initial flight of ProSEDS is scheduled to fly aboard an Air Force Delta II rocket in the summer of 2002. In orbit, ProSEDS will deploy from a Delta II second stage. It will be a 3.1-mile (5 kilometer) long, ultrathin base-wire tether cornected with a 6.2-mile (10 kilometer) long non-conducting tether. This photograph shows Less Johnson, a scientist at MSFC, inspecting the nonconducting part of a tether as it exits a deployer similar to the one to be used in the ProSEDS experiment. The ProSEDS experiment is managed by the Space Transportation Directorate at MSFC.
Strategic Employee Development (SED) Program

NASA Technical Reports Server (NTRS)

Nguyen, Johnny; Guevara (Castano), Nathalie; Thorpe, Barbara; Barnett, Rebecca

2017-01-01

As with many other U.S. agencies, succession planning is becoming a critical need for NASA. The primary drivers include (a) NASAs higher-than-average aged workforce with approximately 50 of employees eligible for retirement within 5 years; and (b) employees who need better developmental conversations to increase morale and retention. This problem is particularly concerning for Safety Mission Assurance (SMA) organizations since they traditionally rely on more experienced engineers and specialists to perform their organizations functions.In response to this challenge, the Kennedy Space Center (KSC) SMA organization created the Strategic Employee Development (SED) program. The SED programs goal is to provide a proactive method to counter the primary drivers by creating a deeper bench strength and providing a more comprehensive developmental feedback experience for the employee. The SED is a new succession planning framework that enables customization to any organization, and in this case, specifically for an SMA organization. This is accomplished via the identification of key positions, the corresponding critical competencies, and a process to help managers have relevant and meaningful development conversations with the workforce. As a result of the SED, several tools and products were created that allows management to make better strategic workforce decisions. Although there are opportunities for improvement for the SED program, the most important impact has been on the quality of developmental discussions for employees.
Pathfinder

NASA Image and Video Library

1999-03-25

Pictured is an artist's concept of NASA's Propulsive Small Expendable Deployer System experiment (ProSEDS). ProSEDS will demonstrate the use of an electrodynamic tether, basically a long, thin wire, for propulsion. An electrodynamic tether uses the same principles as electric motors in toys, appliances and computer disk drives, and generators in automobiles and power plants. When electrical current is flowing through the tether, a magnetic field is produced that pushes against the magnetic field of the Earth. For ProSEDS, the current in the tether results by virtue of the voltage generated when the tether moves through the Earth's magnetic field at more than 17,000 mph. This approach can produce drag thrust generating useable power. Since electrodynamic tethers require no propellant, they could substantially reduce the weight of the spacecraft and provide a cost-effective method of reboosting spacecraft. The initial flight of ProSEDS is scheduled to fly aboard an Air Force Delta II rocket in summer of 2002. In orbit, ProSEDS will deploy from a Delta II second stage. It will be a 3.1-mile (5 kilometer) long, ultrathin base-wire tether cornected with a 6.2-mile (10 kilometer) long nonconducting tether. The ProSEDS experiment is managed by the Space Transportation Directorate at the Marshall Space Flight Center.
Effect of exercise and caloric restriction on DMBA induced mammary tumorigenesis and plasma lipids in rats fed high fat diets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Magrane, D.

1991-03-15

Female Sprague-Dawley rats were given a single 10 mg dose of 7, 12-Dimethylbenz(a)anthracene (DMBA) and grouped as follows: (1) low fat-sedentary (LF-SED), (2) low fat-exercised (LF-EX), (3) high fat-sedentary (HF-SED), (4) high fat-exercised (HF-EX), (5) high fat-caloric restricted (HF-RES). Diets were isocaloric and contained 3.9% (LF) and 19.4% (HF) of corn oil. Group 5 was fed a 25% caloric restricted diet but with 24.6% fat content to equalize fat intake to HF-SED. After 12 weeks of diet or treadmill exercise, tumor data and plasma lipid profiles were determined. Results show that rats on HF-EX had more total tumors, % ofmore » tumors and tumors per tumor bearing rat than rats on HF-SED. The effect of exercise was also evident in LF-EX rats, when compared to LF-SED. Average tumor size and tumor volumes were not affected. The HF-RES group showed reduced tumor profiles compared to HF-SED. HDL, LDL, triglycerides and total cholesterol were unaffected by HF or LF diets or exercise. These data suggest that tumorigenesis is increased by moderate and constant exercise.« less
Is there a relationship between accelerometer-assessed physical activity and sedentary time and cognitive function in U.S. Hispanic/Latino adults? The Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

PubMed Central

Vásquez, Elizabeth; Strizich, Garrett; Isasi, Carmen R; Echeverria, Sandra E; Sotres-Alvarez, Daniela; Evenson, Kelly R.; Gellman, Marc D; Palta, Priya; Qi, Qibin; Lamar, Melissa; Tarraf, Wassim; González, Hector M; Kaplan, Robert

2018-01-01

Normative changes in cognitive function are expected with increasing age. Research on the relationship between normative cognitive decline and moderate-to-vigorous physical activity (MVPA) and sedentary behavior (SED) needs further investigation in Hispanic/Latinos adults. We assessed the cross-sectional association between accelerometer assessed MVPA and SED with cognitive function in 7,478 adults aged 45–74 years from the Hispanic Community Health Study/Study of Latinos. At baseline, cognitive tests included two executive function tests (Digit Symbol Substitution Test (DSST), a test of language (Word Fluency), and a test of memory (Spanish English Verbal Learning Test). Multiple regression models were used to examine associations of time spent in MVPA and SED with cognitive function by age groups, adjusted for age, education, sex, acculturation, and field center. Mean time spent in sedentary behaviors was 12.3 hours/day in females and 11.9 hours/day in males (75% and 77% of accelerometer wear time, respectively). Higher SED, but not MVPA, was associated with lower DSST raw scores (β −0.03 with each 10-min increment in SED; P < 0.05), indicating lower performance in executive function in all age groups. No associations were observed for MVPA and SED with tests of language or memory tests. Our findings suggest a distinct association of SED but not MVPA on executive functioning in middle-aged and older Latino adults. Longitudinal studies are needed to more conclusively determine causal links. PMID:28765082
Sedimentation Efficiency of Condensation Clouds in Substellar Atmospheres

NASA Astrophysics Data System (ADS)

Gao, Peter; Marley, Mark S.; Ackerman, Andrew S.

2018-03-01

Condensation clouds in substellar atmospheres have been widely inferred from spectra and photometric variability. Up until now, their horizontally averaged vertical distribution and mean particle size have been largely characterized using models, one of which is the eddy diffusion–sedimentation model from Ackerman and Marley that relies on a sedimentation efficiency parameter, f sed, to determine the vertical extent of clouds in the atmosphere. However, the physical processes controlling the vertical structure of clouds in substellar atmospheres are not well understood. In this work, we derive trends in f sed across a large range of eddy diffusivities (K zz ), gravities, material properties, and cloud formation pathways by fitting cloud distributions calculated by a more detailed cloud microphysics model. We find that f sed is dependent on K zz , but not gravity, when K zz is held constant. f sed is most sensitive to the nucleation rate of cloud particles, as determined by material properties like surface energy and molecular weight. High surface energy materials form fewer, larger cloud particles, leading to large f sed (>1), and vice versa for materials with low surface energy. For cloud formation via heterogeneous nucleation, f sed is sensitive to the condensation nuclei flux and radius, connecting cloud formation in substellar atmospheres to the objects’ formation environments and other atmospheric aerosols. These insights could lead to improved cloud models that help us better understand substellar atmospheres. For example, we demonstrate that f sed could increase with increasing cloud base depth in an atmosphere, shedding light on the nature of the brown dwarf L/T transition.
Supported education for individuals with psychiatric disabilities: State of the practice and policy implications.

PubMed

Ringeisen, Heather; Langer Ellison, Marsha; Ryder-Burge, Amy; Biebel, Kathleen; Alikhan, Shums; Jones, Emily

2017-06-01

Supported education (SEd) is a promising practice that supports and encourages educational goals and attainment among individuals with psychiatric disabilities. This paper provides insights into how SEd objectives are pursued in different settings, assesses the evidence base, and discusses policy implications. Insights from 3 data sources were synthesized: published literature, an environmental scan, and 3 site visits to programs that support the education goals of individuals with psychiatric disabilities. While setting, target populations, level of coordination with supported employment, and financing strategies varied, common SEd components emerged: specialized and dedicated staffing, one-on-one and group skill-building activities, assistance with navigating the academic setting and coordinating different services, and linkages with mental health counseling. The evidence base is growing; however, many published studies to date do not employ rigorous methodology. Conclusions and Implications for Policy and Practice: Continued specification, operationalization, and testing of SEd core components are needed. The components of the evolving SEd model would benefit from rigorous testing to evaluate impact on degree completion and other key impacts such as employment; health, mental health, or recovery; and community participation. In addition to funding streams from special education and Medicaid, new opportunities for increasing the availability of SEd include the Workforce Innovation and Opportunities Act (WIOA) reauthorization, which requires state vocational rehabilitation agencies to fund preemployment services for transition-age individuals. New "set-aside" requirements for the Mental Health Services Block Grant will increase funding for early intervention services for individuals with serious mental illness, potentially including SEd. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
sedFlow - a tool for simulating fractional bedload transport and longitudinal profile evolution in mountain streams

NASA Astrophysics Data System (ADS)

Heimann, F. U. M.; Rickenmann, D.; Turowski, J. M.; Kirchner, J. W.

2015-01-01

Especially in mountainous environments, the prediction of sediment dynamics is important for managing natural hazards, assessing in-stream habitats and understanding geomorphic evolution. We present the new modelling tool {sedFlow} for simulating fractional bedload transport dynamics in mountain streams. sedFlow is a one-dimensional model that aims to realistically reproduce the total transport volumes and overall morphodynamic changes resulting from sediment transport events such as major floods. The model is intended for temporal scales from the individual event (several hours to few days) up to longer-term evolution of stream channels (several years). The envisaged spatial scale covers complete catchments at a spatial discretisation of several tens of metres to a few hundreds of metres. sedFlow can deal with the effects of streambeds that slope uphill in a downstream direction and uses recently proposed and tested approaches for quantifying macro-roughness effects in steep channels. sedFlow offers different options for bedload transport equations, flow-resistance relationships and other elements which can be selected to fit the current application in a particular catchment. Local grain-size distributions are dynamically adjusted according to the transport dynamics of each grain-size fraction. sedFlow features fast calculations and straightforward pre- and postprocessing of simulation data. The high simulation speed allows for simulations of several years, which can be used, e.g., to assess the long-term impact of river engineering works or climate change effects. In combination with the straightforward pre- and postprocessing, the fast calculations facilitate efficient workflows for the simulation of individual flood events, because the modeller gets the immediate results as direct feedback to the selected parameter inputs. The model is provided together with its complete source code free of charge under the terms of the GNU General Public License (GPL) (www.wsl.ch/sedFlow). Examples of the application of sedFlow are given in a companion article by Heimann et al. (2015).
Effect of a Behavioral Intervention Strategy for Adoption and Maintenance of a Physically Active Lifestyle: The Italian Diabetes and Exercise Study 2 (IDES_2): A Randomized Controlled Trial.

PubMed

Balducci, Stefano; D'Errico, Valeria; Haxhi, Jonida; Sacchetti, Massimo; Orlando, Giorgio; Cardelli, Patrizia; Vitale, Martina; Bollanti, Lucilla; Conti, Francesco; Zanuso, Silvano; Nicolucci, Antonio; Pugliese, Giuseppe

2017-11-01

Adherence to physical activity (PA) recommendations is hampered by the lack of effective strategies to promote behavior change. The Italian Diabetes and Exercise Study 2 (IDES_2) is a randomized controlled trial evaluating a novel behavioral intervention strategy for increasing PA and decreasing sedentary time (SED-time) in patients with type 2 diabetes. The study randomized 300 physically inactive and sedentary patients with type 2 diabetes 1:1 to receive theoretical and practical counseling once yearly for 3 years (intervention group [INT]) or standard care (control group [CON]). Here, we report the 4-month effects on objectively (accelerometer) measured daily light-intensity PA (LPA), moderate-to-vigorous-intensity PA (MVPA), and SED-time, and cardiovascular risk factors. LPA and MVPA both increased, and SED-time decreased in both groups, although changes were significantly more marked in INT participants (approximately twofold for LPA and SED-time and approximately sixfold for MVPA). A significant reduction in HbA 1c was observed only in INT subjects. An increase in LPA >0.92 h · day -1 and in MVPA >7.33 min · day -1 and a decrease in SED-time >1.05 h · day -1 were associated with an average decrease in HbA 1c of ∼1% and also with significant improvements in fasting glucose, body weight, waist circumference, and hs-CRP. Changes in PA and SED-time were independent predictors of improvements in HbA 1c . This behavioral intervention is effective in the short term for increasing LPA and MVPA and reducing SED-time. Significant improvements in cardiometabolic risk profiles were observed in subjects experiencing the most pronounced changes in PA and SED-time, even if below the recommended level. © 2017 by the American Diabetes Association.
Effects of exercise and L-arginine on ventricular remodeling and oxidative stress.

PubMed

Xu, Xiaohua; Zhao, Weiyan; Lao, Shunhua; Wilson, Bryan S; Erikson, John M; Zhang, John Q

2010-02-01

Our aim was to characterize the changes in messenger RNA (mRNA) abundance, protein, and activity levels of the enzymatic antioxidants, superoxide dismutase (SOD), glutathione peroxidase, and catalase by exercise training combined with L-arginine after myocardial infarction (MI). L-Arginine (1 g x kg(-1) x d(-1)) and N(G)-nitro-L-arginine methyl ester (L-NAME; 10 mg x kg(-1) x d(-1)) were administered in drinking water for 8 wk. Sprague-Dawley rats were randomized to the following groups: sham-operated control (Sham); MI sedentary (Sed); MI exercise (Ex); MI sedentary + L-arginine (Sed + LA); MI exercise + L-arginine (Ex + LA); MI sedentary + L-NAME (Sed + L-NAME); and MI exercise + L-NAME (Ex + L-NAME). The glutathione peroxidase, catalase, and gp91(phox) mRNA levels were comparable among all the groups. The SOD mRNA level was significantly increased in the Ex group (5.43 +/- 0.87) compared with the Sed group (1.74 +/- 0.29), whereas this effect was pronouncedly down-regulated by the L-NAME intervention (2.51 +/- 1.17, P < 0.05). The protein levels of SOD in the Sed and Ex groups were both significantly decreased with the administration of L-NAME. The protein levels of catalase were significantly higher in the Ex and Ex + LA groups than that in the Sed, Sed + LA, and L-NAME-treated groups. The collagen volume fraction was significantly lowered by the exercise and/or L-arginine treatment when compared with the Sed group. Fractional shortening was significantly preserved in the trained groups compared with their corresponding sedentary groups with or without drug treatments. However, the beneficial effect was not further improved by L-arginine treatment. Our results suggest that exercise training exerts antioxidative effects and attenuates myocardial fibrosis in the MI rats. These improvements, in turn, alleviate cardiac stiffness and preserve post-MI cardiac function. In addition, L-arginine appears to have no additive effect on cardiac function or expression of enzymatic antioxidants.
Geographic Variation in Maternal Smoking during Pregnancy in the Missouri Adolescent Female Twin Study (MOAFTS)

PubMed Central

Lian, Min; Madden, Pamela A.; Lynskey, Michael T.; Colditz, Graham A.; Lessov-Schlaggar, Christina N.; Schootman, Mario; Heath, Andrew C.

2016-01-01

Objective Despite well-known adverse health effects of maternal smoking during pregnancy (MSP), it is still unclear if MSP varies geographically and if neighborhood socioeconomic deprivation (SED) plays an important role in MSP. This study aims to investigate small-area geographic variation in MSP and examine the association of SED with MSP. Methods The Missouri Adolescent Female Twin Study (MOAFTS) is a cohort study of female like-sex twins born in Missouri to Missouri-resident parents during 1975–1985. Biological mothers completed a baseline interview in 1995–1998 and reported MSP with the twins. Residential address of the mother at birth was geocoded. We developed a census tract-level SED index using a common factor approach based on 21 area-level socioeconomic variables from the 1980 Census data. Multilevel logistic regressions estimated geographic heterogeneity (random effect) in MSP and the odds ratios (ORs, fixed effects) of neighborhood SED associated with MSP. Results Of 1658 MOAFTS mothers, 35.2% reported any MSP and 21.9% reported MSP beyond the first trimester. Neighborhood SED was associated with any MSP (the highest vs. the lowest quartile: OR = 1.90, 95% confidence interval [CI] = 1.40–2.57, Ptrend<0.001) and MSP beyond the first trimester (OR = 1.98, 95% CI = 1.38–2.85, Ptrend = 0.002) in unadjusted analyses. After adjusting for individual covariates (demographics, socioeconomic conditions, alcohol use, and parents’ cohabitation), neighborhood SED was not associated with MSP, but geographic variation still persisted in MSP (variance = 0.41, P = 0.003) and in MSP beyond the first trimester (variance = 0.82, P<0.001). Conclusions Neighborhood SED was associated with MSP in unadjusted analyses but this association could be explained by individual socioeconomic conditions. Nonetheless, significant geographic variation in MSP persisted and was not accounted for by differences in neighborhood SED. To develop effective interventions to reduce MSP, further studies are necessary to explore underlying reasons for its geographic variation. PMID:27100091
Continuous monitoring bed-level dynamics on an intertidal flat: introducing novel stand-alone high-resolution SED-sensors

NASA Astrophysics Data System (ADS)

Hu, Zhan; Lenting, Walther; van der Wal, Daphne; Bouma, Tjeerd

2015-04-01

Tidal flat morphology is continuously shaped by hydrodynamic force, resulting in highly dynamic bed elevations. The knowledge of short-term bed-level changes is important both for understanding sediment transport processes as well as for assessing critical ecological processes such as e.g. vegetation recruitment chances on tidal flats. Due to the labour involved, manual discontinuous measurements lack the ability to continuously monitor bed-elevation changes. Existing methods for automated continuous monitoring of bed-level changes lack vertical accuracy (e.g., Photo-Electronic Erosion Pin sensor and resistive rod) or limited in spatial application by using expensive technology (e.g., acoustic bed level sensors). A method provides sufficient accuracy with a reasonable cost is needed. In light of this, a high-accuracy sensor (2 mm) for continuously measuring short-term Surface-Elevation Dynamics (SED-sensor) was developed. This SED-sensor makes use of photovoltaic cells and operates stand-alone using internal power supply and data logging system. The unit cost and the labour in deployments is therefore reduced, which facilitates monitoring with a number of units. In this study, the performance of a group of SED-sensors is tested against data obtained with precise manual measurements using traditional Sediment Erosion Bars (SEB). An excellent agreement between the two methods was obtained, indicating the accuracy and precision of the SED-sensors. Furthermore, to demonstrate how the SED-sensors can be used for measuring short-term bed-level dynamics, two SED-sensors were deployed for 1 month at two sites with contrasting wave exposure conditions. Daily bed-level changes were obtained including a severe storm erosion event. The difference in observed bed-level dynamics at both sites was statistically explained by their different hydrodynamic conditions. Thus, the stand-alone SED-sensor can be applied to monitor sediment surface dynamics with high vertical and temporal resolutions, which provides opportunities to pinpoint morphological responses to various forces in a number of environments (e.g. tidal flats, beaches, rivers and dunes).
Estimating Last Glacial Maximum Ice Thickness Using Porosity and Depth Relationships: Examples from AND-1B and AND-2A Cores, McMurdo Sound, Antarctica

NASA Astrophysics Data System (ADS)

Hayden, T. G.; Kominz, M. A.; Magens, D.; Niessen, F.

2009-12-01

We have estimated ice thicknesses at the AND-1B core during the Last Glacial Maximum by adapting an existing technique to calculate overburden. As ice thickness at Last Glacial Maximum is unknown in existing ice sheet reconstructions, this analysis provides constraint on model predictions. We analyze the porosity as a function of depth and lithology from measurements taken on the AND-1B core, and compare these results to a global dataset of marine, normally compacted sediments compiled from various legs of ODP and IODP. Using this dataset we are able to estimate the amount of overburden required to compact the sediments to the porosity observed in AND-1B. This analysis is a function of lithology, depth and porosity, and generates estimates ranging from zero to 1,000 meters. These overburden estimates are based on individual lithologies, and are translated into ice thickness estimates by accounting for both sediment and ice densities. To do this we use a simple relationship of Xover * (ρsed/ρice) = Xice; where Xover is the overburden thickness, ρsed is sediment density (calculated from lithology and porosity), ρice is the density of glacial ice (taken as 0.85g/cm3), and Xice is the equalivant ice thickness. The final estimates vary considerably, however the “Best Estimate” behavior of the 2 lithologies most likely to compact consistently is remarkably similar. These lithologies are the clay and silt units (Facies 2a/2b) and the diatomite units (Facies 1a) of AND-1B. These lithologies both produce best estimates of approximately 1,000 meters of ice during Last Glacial Maximum. Additionally, while there is a large range of possible values, no combination of reasonable lithology, compaction, sediment density, or ice density values result in an estimate exceeding 1,900 meters of ice. This analysis only applies to ice thicknesses during Last Glacial Maximum, due to the overprinting effect of Last Glacial Maximum on previous ice advances. Analysis of the AND-2A core is underway, and results will be compared to those of AND-1B.
Screwworm Eradication Data System (SEDS) applications program documentation, part 2

NASA Technical Reports Server (NTRS)

1976-01-01

National Oceanic and Atmospheric Administration (NOAA) satellite data, which is in analog tape form, is converted into output data products. These products are used by investigators in determining optimum areas for airdrops of steril screwworm flies over Mexico. The output product of SEDS takes the form of imagery data film slides showing Mexico and the lower southwest portion of the United States. The area analog preprocessing phase of the SEDS task is covered.
JPRS Report, East Europe.

DTIC Science & Technology

1990-01-19

how maintainable a building is, really met until the invention of the internal combustion how modernizable. In the future these qualities must be...Academy of the GDR], 1. "Bericht des Zentralkomitees der SED an den XI. Bauakademie, Berlin, 1981, p 12. Parteitag der SED" [Report of the Central...by all-around brigades highly skilled in a number of trades, combinable small 3. Cf. "Bericht des Zentralkomitees der SED an den XI. units from Kreis
Reduction of low frequency error for SED36 and APS based HYDRA star trackers

NASA Astrophysics Data System (ADS)

Ouaknine, Julien; Blarre, Ludovic; Oddos-Marcel, Lionel; Montel, Johan; Julio, Jean-Marc

2017-11-01

In the frame of the CNES Pleiades satellite, a reduction of the star tracker low frequency error, which is the most penalizing error for the satellite attitude control, was performed. For that purpose, the SED36 star tracker was developed, with a design based on the flight qualified SED16/26. In this paper, the SED36 main features will be first presented. Then, the reduction process of the low frequency error will be developed, particularly the optimization of the optical distortion calibration. The result is an attitude low frequency error of 1.1" at 3 sigma along transverse axes. The implementation of these improvements to HYDRA, the new multi-head APS star tracker developed by SODERN, will finally be presented.
ESR

MedlinePlus

Erythrocyte sedimentation rate; Sed rate; Sedimentation rate ... Reasons why a "sed rate" may be done include: Unexplained fevers Certain types of arthritis Muscle symptoms Other vague symptoms that cannot be explained This ...
ALMA Reveals a Compact Starburst Around a Hidden QSO at z˜5

NASA Astrophysics Data System (ADS)

Gilli, R.; Norman, C. A.; Vignali, C.

2015-12-01

We present ALMA 1.3mm observations of XID403, an SMG at z=4.75 in the Chandra Deep Field South hosting a heavily obscured, Compton-thick QSO. The ALMA data show that the dust heated by star formation is distributed within ˜0.9 kpc from the nucleus (effective radius). The SFR and dust temperature obtained from the Herschel+ALMA far-IR SED, reveal a warm and compact starburst with surface density of 200 M⊙ yr-1 kpc-2. Our analysis suggest that, besides the mass, SFR and gas consumption timescale, objects like XID403 have also the right size to be the progenitors of the compact quiescent massive galaxies seen at z˜3. It is finally shown that the density of the gas co-spatial with the dust provides a substantial contribution to the absorbing column density towards the QSO as measured from the X-rays.

Is POEM the Answer for Management of Spastic Esophageal Disorders? A Systematic Review and Meta-Analysis.

PubMed

Khan, Muhammad Ali; Kumbhari, Vivek; Ngamruengphong, Saowanee; Ismail, Amr; Chen, Yen-I; Chavez, Yamile Haito; Bukhari, Majidah; Nollan, Richard; Ismail, Mohammad Kashif; Onimaru, Manabu; Balassone, Valerio; Sharata, Ahmed; Swanstrom, Lee; Inoue, Haruhiro; Repici, Alessandro; Khashab, Mouen A

2017-01-01

Spastic esophageal disorders (SEDs) include spastic achalasia (type III), diffuse esophageal spasm (DES), and nutcracker/jackhammer esophagus (JH). Per-oral endoscopic myotomy (POEM) has demonstrated efficacy and safety in the treatment of achalasia. Recently, POEM has been indicated for the treatment of SEDs. We conducted a systematic review and meta-analysis to determine the clinical success and safety of POEM in SEDs. We searched several databases from 01/01/2007 to 01/10/2016 to identify studies (with five or more patients) on POEM for the treatment of SEDs. Weighted pooled rates (WPRs) for clinical success and adverse events (AEs) were calculated for all SEDs. Clinical success was defined as Eckardt scores of ≤3 and/or improvement in severity of dysphagia based on achalasia disease-specific health-related quality of life questionnaire. The WPRs for clinical success and AEs were analyzed using fixed- or random-effects model based on heterogeneity. The proportionate difference in clinical success and post-procedure adverse event rates among individual types of SEDs was also calculated. A total of eight observational studies with 179 patients were included in the final analysis. Two studies were of good quality and six were of fair quality based on the National Institutes of Health quality assessment tool. The WPR with 95% confidence interval (CI) for cumulative clinical success of POEM in all SEDs was 87% (78, 93%), I 2 = 37%. The total number of patients for individual disorders, i.e., type III achalasia, JH, and DES, was 116, 37, and 18, respectively. The WPRs for clinical success of POEM for type III achalasia, DES, and JH were 92, 88, and 72%, respectively. Proportion difference of WPR for clinical success was significantly higher for type III achalasia in comparison with JH (20%, P = 0.01). The WPR with 95% CI for AEs of POEM in all SEDs was 14% (9, 20%), I 2 = 0%. The WPRs for post-procedure adverse events for type III achalasia, DES, and JH were 11, 14, and 16%, respectively. There was no difference in safety of POEM among individual SEDs. POEM is an effective and safe therapeutic modality for the treatment of spastic esophageal disorders.
Fine structure of Galactic foreground ISM towards high-redshift AGN - utilizing Herschel PACS and SPIRE data

NASA Astrophysics Data System (ADS)

Perger, K.; Pinter, S.; Frey, S.; Tóth, L. V.

2018-05-01

One of the most certain ways to determine star formation rate in galaxies is based on far infrared (FIR) measurements. To decide the origin of the observed FIR emission, subtracting the Galactic foreground is a crucial step. We utilized Herschel photometric data to determine the hydrogen column densities in three galactic latitude regions, at b = 27°, 50° and -80°. We applied a pixel-by-pixel fit to the spectral energy distribution (SED) for the images aquired from parallel PACS-SPIRE observations in all three sky areas. We determined the column densities with resolutions 45'' and 6', and compared the results with values estimated from the IRAS dust maps. Column densities at 27° and 50° galactic latitudes determined from the Herschel data are in a good agreement with the literature values. However, at the highest galactic latitude we found that the column densities from the Herschel data exceed those derived from the IRAS dust map.
Pixel-by-Pixel SED Fitting of Intermediate Redshift Galaxies

NASA Astrophysics Data System (ADS)

Cohen, Seth H.; Kim, Hwihyun; Petty, Sara M.; Farrah, Duncan

2015-01-01

We select intermediate redshift galaxies from the Hubble Space Telescope CANDELS and GOODS surveys to study their stellar populations on sub-kilo-parsec scales by fitting SED models on a pixel-by-pixel basis. Galaxies are chosen to have measured spectroscopic redshifts (z<1.5), to be bright (H_AB<21 mag), to be relatively face-on (b/a > 0.6), and have a minimum of ten individual resolution elements across the face of the galaxy, as defined by the broadest PSF (F160W-band) in the data. The sample contains ~200 galaxies with BViz(Y)JH band HST photometry. The main goal of the study is to better understand the effects of population blending when using a pixel-by-pixel SED fitting (pSED) approach. We outline our pSED fitting method which gives maps of stellar mass, age, star-formation rate, etc. Several examples of individual pSED-fit maps are presented in detail, as well as some preliminary results on the full sample. The pSED method is necessarily biased by the brightest population in a given pixel outshining the rest of the stars, and, therefore, we intend to study this apparent population blending in a set of artificially redshifted images of nearby galaxies, for which we have star-by-star measurements of their stellar populations. This local sample will be used to better interpret the measurements for the higher redshift galaxies.Based on observations made with the NASA/ESA Hubble Space Telescope, obtained from the Data Archive at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555. This archival research is associated with program #13241.
Early postweaning exercise improves central leptin sensitivity in offspring of rat dams fed high-fat diet during pregnancy and lactation.

PubMed

Sun, Bo; Liang, Nu-Chu; Ewald, Erin R; Purcell, Ryan H; Boersma, Gretha J; Yan, Jianqun; Moran, Timothy H; Tamashiro, Kellie L K

2013-11-01

Maternal high-fat (HF) diet has long-term consequences on the metabolic phenotype of the offspring. Here, we determined the effects of postweaning exercise in offspring of rat dams fed HF diet during gestation and lactation. Pregnant Sprague-Dawley rats were maintained on chow or HF diet throughout gestation and lactation. All pups were weaned onto chow diet on postnatal day (PND) 21. At 4 wk of age, male pups were given free access to running wheels (RW) or remained sedentary (SED) for 3 wk, after which all rats remained sedentary, resulting in four groups: CHOW-SED, CHOW-RW, HF-SED, and HF-RW. Male HF offspring gained more body weight by PND7 compared with CHOW pups and maintained this weight difference through the entire experiment. Three weeks of postweaning exercise did not affect body weight gain in either CHOW or HF offspring, but reduced adiposity in HF offspring. Plasma leptin was decreased at the end of the 3-wk running period in HF-RW rats but was not different from HF-SED 9 wk after the exercise period ended. At 14 wk of age, intracerebroventricular injection of leptin suppressed food intake in CHOW-SED, CHOW-RW, and HF-RW, while it did not affect food intake in HF-SED group. At death, HF-RW rats also had higher leptin-induced phospho-STAT3 level in the arcuate nucleus than HF-SED rats. Both maternal HF diet and postweaning exercise had effects on hypothalamic neuropeptide and receptor mRNA expression in adult offspring. Our data suggest that postweaning exercise improves central leptin sensitivity and signaling in this model.
THE INFLUENCE OF THE EXTREME ULTRAVIOLET SPECTRAL ENERGY DISTRIBUTION ON THE STRUCTURE AND COMPOSITION OF THE UPPER ATMOSPHERE OF EXOPLANETS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guo, J. H.; Ben-Jaffel, Lotfi, E-mail: guojh@ynao.ac.cn, E-mail: bjaffel@iap.fr

2016-02-20

By varying the profiles of stellar extreme ultraviolet (EUV) spectral energy distributions (SEDs), we tested the influences of stellar EUV SEDs on the physical and chemical properties of an escaping atmosphere. We apply our model to study four exoplanets: HD 189733b, HD 209458b, GJ 436b, and Kepler-11b. We find that the total mass loss rates of an exoplanet, which are determined mainly by the integrated fluxes, are moderately affected by the profiles of the EUV SED, but the composition and species distributions in the atmosphere can be dramatically modified by the different profiles of the EUV SED. For exoplanets withmore » a high hydrodynamic escape parameter (λ), the amount of atomic hydrogen produced by photoionization at different altitudes can vary by one to two orders of magnitude with the variation of stellar EUV SEDs. The effect of photoionization of H is prominent when the EUV SED is dominated by the low-energy spectral region (400–900 Å), which pushes the transition of H/H{sup +} to low altitudes. In contrast, the transition of H/H{sup +} moves to higher altitudes when most photons are concentrated in the high-energy spectral region (50–400 Å). For exoplanets with a low λ, the lower temperatures of the atmosphere make many chemical reactions so important that photoionization alone can no longer determine the composition of the escaping atmosphere. For HD 189733b, it is possible to explain the time variability of Lyα between 2010 and 2011 by a change in the EUV SED of the host K-type star, yet invoking only thermal H i in the atmosphere.« less
High intensity interval training (HIIT) improves resting blood pressure, metabolic (MET) capacity and heart rate reserve without compromising cardiac function in sedentary aging men.

PubMed

Grace, Fergal; Herbert, Peter; Elliott, Adrian D; Richards, Jo; Beaumont, Alexander; Sculthorpe, Nicholas F

2017-05-13

This study examined a programme of pre-conditioning exercise with subsequent high intensity interval training (HIIT) on blood pressure, echocardiography, cardiac strain mechanics and maximal metabolic (MET) capacity in sedentary (SED) aging men compared with age matched masters athletes (LEX). Using a STROBE compliant observational design, 39 aging male participants (SED; n=22, aged 62.7±5.2yrs) (LEX; n=17, aged=61.1±5.4yrs) were recruited to a study that necessitated three distinct assessment phases; enrolment (Phase A), following pre-conditioning exercise in SED (Phase B), then following 6weeks of HIIT performed once every five days by both groups before reassessment (Phase C). Hemodynamic, echocardiographic and cardiac strain mechanics were obtained at rest and maximal cardiorespiratory and chronotropic responses were obtained at each measurement phase. The training intervention improved systolic, mean arterial blood pressure, rate pressure product and heart rate reserve (each P<0.05) in SED and increased MET capacity in both SED and LEX (P<0.01) which was amplified by HIIT. Echocardiography and cardiac strain measures were unremarkable apart from trivial increase to intra-ventricular septum diastole (IVSd) (P<0.05) and decrease to left ventricular internal dimension diastole (LVId) (P<0.05) in LEX following HIIT. A programme of preconditioning exercise with HIIT induces clinically relevant improvements in blood pressure, rate pressure product and encourages recovery of heart rate reserve in SED, while improving maximal MET capacity in both SED and LEX without inducing any pathological cardiovascular remodeling. These data add to the emerging repute of HIIT as a safe and promising exercise prescription to improve cardiovascular function and metabolic capacity in sedentary aging. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.
Socioeconomic deprivation and survival after stroke: findings from the prospective South London Stroke Register of 1995 to 2011.

PubMed

Chen, Ruoling; McKevitt, Christopher; Rudd, Anthony G; Wolfe, Charles D A

2014-01-01

Previous findings of the association between socioeconomic deprivation (SED) and survival after stroke are inconsistent. There is less investigation on long-term survival. We assessed the associations in a multi-ethnic population in England. We examined data from 4398 patients (3103 whites, 932 blacks, and 253 Asians/others) with first-ever stroke, collected by a population-based stroke register in South London from 1995 to 2011. SED was measured using the Carstairs index score-the higher score, the more deprived. It was analyzed in multivariate Cox regression models in relation to survival after stroke. During 17-year follow-up 2754 patients died. The quartile data of Carstairs score showed no significant association of SED with survival in patients, except for black Caribbeans and Africans. Black patients with the fourth quartile SED had a multivariate adjusted hazard ratio of 1.76 (95% confidence interval, 1.06-2.94) for 3-month mortality and 1.54 (1.00-2.37) for 1-year mortality. After adjustment for acute stroke care provisions, these were no longer significant. However, the sextile data of Carstairs score showed a consistent association of SED with survival after stroke; all patients with the sixth sextile had a fully adjusted hazard ratio of 1.23 (1.05-1.44) for 3-month mortality and 1.13 (1.01-1.25) for 17-year mortality. There is a weak but significant association of SED with reduced survival after stroke in England. SED in blacks may have a stronger impact on short-term survival when compared with white patients. Further efforts are required to achieve equality in survival among patients with stroke of different socioeconomic groups.
Overview of Advanced Space Propulsion Activities in the Space Environmental Effects Team at MSFC

NASA Technical Reports Server (NTRS)

Edwards, David; Carruth, Ralph; Vaughn, Jason; Schneider, Todd; Kamenetzky, Rachel; Gray, Perry

2000-01-01

Exploration of our solar system, and beyond, requires spacecraft velocities beyond our current technological level. Technologies addressing this limitation are numerous. The Space Environmental Effects (SEE) Team at the Marshall Space Flight Center (MSFC) is focused on three discipline areas of advanced propulsion; Tethers, Beamed Energy, and Plasma. This presentation will give an overview of advanced propulsion related activities in the Space Environmental Effects Team at MSFC. Advancements in the application of tethers for spacecraft propulsion were made while developing the Propulsive Small Expendable Deployer System (ProSEDS). New tether materials were developed to meet the specifications of the ProSEDS mission and new techniques had to be developed to test and characterize these tethers. Plasma contactors were developed, tested and modified to meet new requirements. Follow-on activities in tether propulsion include the Air-SEDS activity. Beamed energy activities initiated with an experimental investigation to quantify the momentum transfer subsequent to high power, 5J, ablative laser interaction with materials. The next step with this experimental investigation is to quantify non-ablative photon momentum transfer. This step was started last year and will be used to characterize the efficiency of solar sail materials before and after exposure to Space Environmental Effects (SEE). Our focus with plasma, for propulsion, concentrates on optimizing energy deposition into a magnetically confined plasma and integration of measurement techniques for determining plasma parameters. Plasma confinement is accomplished with the Marshall Magnetic Mirror (M3) device. Initial energy coupling experiments will consist of injecting a 50 amp electron beam into a target plasma. Measurements of plasma temperature and density will be used to determine the effect of changes in magnetic field structure, beam current, and gas species. Experimental observations will be compared to predictions from computer modeling.
PdBI cold dust imaging of two extremely red H – [4.5] > 4 galaxies discovered with SEDS and CANDELS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Caputi, K. I.; Popping, G.; Spaans, M.

2014-06-20

We report Plateau de Bure Interferometer (PdBI) 1.1 mm continuum imaging toward two extremely red H – [4.5] > 4 (AB) galaxies at z > 3, which we have previously discovered making use of Spitzer SEDS and Hubble Space Telescope CANDELS ultra-deep images of the Ultra Deep Survey field. One of our objects is detected on the PdBI map with a 4.3σ significance, corresponding to S{sub ν}(1.1 mm)=0.78±0.18 mJy. By combining this detection with the Spitzer 8 and 24 μm photometry for this source, and SCUBA2 flux density upper limits, we infer that this galaxy is a composite active galacticmore » nucleus/star-forming system. The infrared (IR)-derived star formation rate is SFR ≈ 200 ± 100 M {sub ☉} yr{sup –1}, which implies that this galaxy is a higher-redshift analogue of the ordinary ultra-luminous infrared galaxies more commonly found at z ∼ 2-3. In the field of the other target, we find a tentative 3.1σ detection on the PdBI 1.1 mm map, but 3.7 arcsec away of our target position, so it likely corresponds to a different object. In spite of the lower significance, the PdBI detection is supported by a close SCUBA2 3.3σ detection. No counterpart is found on either the deep SEDS or CANDELS maps, so, if real, the PdBI source could be similar in nature to the submillimeter source GN10. We conclude that the analysis of ultra-deep near- and mid-IR images offers an efficient, alternative route to discover new sites of powerful star formation activity at high redshifts.« less
How low can dietary greenhouse gas emissions be reduced without impairing nutritional adequacy, affordability and acceptability of the diet? A modelling study to guide sustainable food choices.

PubMed

Perignon, Marlène; Masset, Gabriel; Ferrari, Gaël; Barré, Tangui; Vieux, Florent; Maillot, Matthieu; Amiot, Marie-Josèphe; Darmon, Nicole

2016-10-01

To assess the compatibility between reduction of diet-related greenhouse gas emissions (GHGE) and nutritional adequacy, acceptability and affordability dimensions of diet sustainability. Dietary intake, nutritional composition, GHGE and prices were combined for 402 foods selected among those most consumed by participants of the Individual National Study on Food Consumption. Linear programming was used to model diets with stepwise GHGE reductions, minimized departure from observed diet and three scenarios of nutritional constraints: none (FREE), on macronutrients (MACRO) and for all nutrient recommendations (ADEQ). Nutritional quality was assessed using the mean adequacy ratio (MAR) and solid energy density (SED). France. Adults (n 1899). In FREE and MACRO scenarios, imposing up to 30 % GHGE reduction did not affect the MAR, SED and food group pattern of the observed diet, but required substitutions within food groups; higher GHGE reductions decreased diet cost, but also nutritional quality, even with constraints on macronutrients. Imposing all nutritional recommendations (ADEQ) increased the fruits and vegetables quantity, reduced SED and slightly increased diet cost without additional modifications induced by the GHGE constraint up to 30 % reduction; higher GHGE reductions decreased diet cost but required non-trivial dietary shifts from the observed diet. Not all the nutritional recommendations could be met for GHGE reductions ≥70 %. Moderate GHGE reductions (≤30 %) were compatible with nutritional adequacy and affordability without adding major food group shifts to those induced by nutritional recommendations. Higher GHGE reductions either impaired nutritional quality, even when macronutrient recommendations were imposed, or required non-trivial dietary shifts compromising acceptability to reach nutritional adequacy.
The Radio Spectral Energy Distribution and Star-formation Rate Calibration in Galaxies

NASA Astrophysics Data System (ADS)

Tabatabaei, F. S.; Schinnerer, E.; Krause, M.; Dumas, G.; Meidt, S.; Damas-Segovia, A.; Beck, R.; Murphy, E. J.; Mulcahy, D. D.; Groves, B.; Bolatto, A.; Dale, D.; Galametz, M.; Sandstrom, K.; Boquien, M.; Calzetti, D.; Kennicutt, R. C.; Hunt, L. K.; De Looze, I.; Pellegrini, E. W.

2017-02-01

We study the spectral energy distribution (SED) of the radio continuum (RC) emission from the Key Insight in Nearby Galaxies Emitting in Radio (KINGFISHER) sample of nearby galaxies to understand the energetics and origin of this emission. Effelsberg multi-wavelength observations at 1.4, 4.8, 8.4, and 10.5 GHz combined with archive data allow us, for the first time, to determine the mid-RC (1-10 GHz, MRC) bolometric luminosities and further present calibration relations versus the monochromatic radio luminosities. The 1-10 GHz radio SED is fitted using a Bayesian Markov Chain Monte Carlo technique leading to measurements for the nonthermal spectral index ({S}ν ˜ {ν }-{α {nt}}) and the thermal fraction ({f}{th}) with mean values of {α }{nt}=0.97 +/- 0.16(0.79 +/- 0.15 for the total spectral index) and {f}{th} = (10 ± 9)% at 1.4 GHz. The MRC luminosity changes over ˜3 orders of magnitude in the sample, 4.3× {10}2 {L}⊙ < MRC < 3.9× {10}5 {L}⊙ . The thermal emission is responsible for ˜23% of the MRC on average. We also compare the extinction-corrected diagnostics of the star-formation rate (SFR) with the thermal and nonthermal radio tracers and derive the first star-formation calibration relations using the MRC radio luminosity. The nonthermal spectral index flattens with increasing SFR surface density, indicating the effect of the star-formation feedback on the cosmic-ray electron population in galaxies. Comparing the radio and IR SEDs, we find that the FIR-to-MRC ratio could decrease with SFR, due to the amplification of the magnetic fields in star-forming regions. This particularly implies a decrease in the ratio at high redshifts, where mostly luminous/star-forming galaxies are detected.
Light-intensity and high-intensity interval training improve cardiometabolic health in rats.

PubMed

Batacan, Romeo B; Duncan, Mitch J; Dalbo, Vincent J; Connolly, Kylie J; Fenning, Andrew S

2016-09-01

Physical activity has the potential to reduce cardiometabolic risk factors but evaluation of different intensities of physical activity and the mechanisms behind their health effects still need to be fully established. This study examined the effects of sedentary behaviour, light-intensity training, and high-intensity interval training on biometric indices, glucose and lipid metabolism, inflammatory and oxidative stress markers, and vascular and cardiac function in adult rats. Rats (12 weeks old) were randomly assigned to 1 of 4 groups: control (CTL; no exercise), sedentary (SED; no exercise and housed in small cages to reduce activity), light-intensity trained (LIT; four 30-min exercise bouts/day at 8 m/min separated by 2-h rest period, 5 days/week), and high-intensity interval trained (HIIT, four 2.5-min work bouts/day at 50 m/min separated by 3-min rest periods, 5 days/week). After 12 weeks of intervention, SED had greater visceral fat accumulation (p < 0.01) and slower cardiac conduction (p = 0.04) compared with the CTL group. LIT and HIIT demonstrated beneficial changes in body weight, visceral and epididymal fat weight, glucose regulation, low-density lipoprotein cholesterol, total cholesterol, and mesenteric vessel contractile response compared with the CTL group (p < 0.05). LIT had significant improvements in insulin sensitivity and cardiac conduction compared with the CTL and SED groups whilst HIIT had significant improvements in systolic blood pressure and endothelium-independent vasodilation to aorta and mesenteric artery compared with the CTL group (p < 0.05). LIT and HIIT induce health benefits by improving traditional cardiometabolic risk factors. LIT improves cardiac health while HIIT promotes improvements in vascular health.
Pathfinder

NASA Image and Video Library

1999-03-01

NASA's Propulsive Small Expendable Deployer System experiment (ProSEDS) will demonstrate the use of an electrodynamic tether, basically a long, thin wire, for propulsion. An electrodynamic tether uses the same principles as electric motors in toys, appliances and computer disk drives, and generators in automobiles and power plants. When electrical current is flowing through the tether, a magnetic field is produced that pushes against the magnetic field of the Earth. For ProSEDS, the current in the tether results by virtue of the voltage generated when the tether moves through the Earth's magnetic field at more than 17,000 mph. This approach can produce drag thrust generating useable power. Since electrodynamic tethers require no propellant, they could substantially reduce the weight of the spacecraft and provide a cost-effective method of reboosting spacecraft. The initial flight of ProSEDS is scheduled to fly aboard an Air Force Delta II rocket in the summer of 2002. In orbit, ProSEDS will deploy from a Delta II second stage. It will be a 3.1-mile (5 kilometer) long, ultrathin base-wire cornected with a 6.2-mile (10 kilometer) long nonconducting tether. This photograph shows Less Johnson, a scientist at MSFC inspecting the nonconducting part of a tether as it exits a deployer similar to the one to be used in the ProSEDS experiment. The ProSEDS experiment is managed by the Space Transportation Directorate at MSFC.
Propulsive Small Expendable Deployer System (ProSEDS)

NASA Technical Reports Server (NTRS)

1999-01-01

This Quick Time movie is of NASA's Propulsive Small Expendable Deployer System experiment (ProSEDS). ProSEDS will demonstrate the use of an electrodynamic tether, basically a long, thin wire, for propulsion. An electrodynamic tether uses the same principles as electric motors in toys, appliances and computer disk drives, and generators in automobiles and power plants. When electrical current is flowing through the tether, a magnetic field is produced that pushes against the magnetic field of the Earth. For ProSEDS, the current in the tether results by virtue of the voltage generated when the tether moves through the Earth's magnetic field at more than 17,000 mph. This approach can produce drag thrust generating useable power. Since electrodynamic tethers require no propellant, they could substantially reduce the weight of the spacecraft and provide a cost-effective method of reboosting spacecraft. The tether would be a 3.1-mile (5 kilometer) long, ultrathin base-wire tether connected with a 6.2-mile (10 kilometer) long nonconducting tether. The ProSEDS experiment is managed by the Space Transportation Directorate at the Marshall Space Flight Center.
Fitting the spectral energy distributions of galaxies with CIGALE : Code Investigating GALaxy Emission

NASA Astrophysics Data System (ADS)

Giovannoli, E.; Buat, V.

2013-03-01

We use the code CIGALE (Code Investigating Galaxies Emission: Burgarella et al. 2005; Noll et al. 2009) which provides physical information about galaxies by fitting their UV (ultraviolet)-to-IR (infrared) spectral energy distribuition (SED). CIGALE is based on the use of a UV-optical stellar SED plus a dust IR-emitting component. We study a sample of 136 Luminous Infrared Galaxies (LIRGs) at z˜0.7 in the ECDF-S previously studied in Giovannoli et al. (2011). We focus on the way the empirical Dale & Helou (2002) templates reproduce the observed SEDs of the LIRGs. Fig. 1 shows the total infrared luminosity (L IR ) provided by CIGALE using the 64 templates (x axis) and using 2 templates (y axis) representative of the whole sample. Despite the larger dispersion when only 1 or 2 Herschel data are available, the agreement between both values is good with Δ log L IR = 0.0013 ± 0.045 dex. We conclude that 2 IR SEDs can be used alone to determine the L IR of LIRGs at z˜0.7 in an SED-fitting procedure.
The Study on the Physical Properties of Blazar Jets

NASA Astrophysics Data System (ADS)

Kang, S. J.

2017-09-01

Active galactic nuclei (AGNs) belong to a special class of active galaxies, and have violent active phenomena and intense physical processes in the nuclei. Blazar is a subclass of AGNs, and has a relativistic jet with a small jet viewing angle. Therefore, the boosting effect is very important, and almost all the observed radiation is dominated by the jet. The relativistic jet physics is not very clear yet, such as the jet formation, collimation, and matter content etc. The multi-waveband radiation of blazar is dominated by jet, which provides an ideal laboratory for studying the jet physics. The first chapter of this thesis introduces the recent progress of AGNs and blazars. We further introduce the jet model that commonly used in blazars in the second chapter. In the third chapter, we fit simultaneously (or quasi-simultaneously) the multi-waveband spectral energy distributions (SEDs) for a sample of low-synchrotron-peaked (LSP) blazars with the jet model and χ2 procedure, which takes into account different soft photon fields (broad line region or a molecular torus). We find that the SED fitting with an external soft photon from IR torus is systematically better than that from the broad line region (BLR) based on a χ2 test, which suggests that the γ-ray emitting region most possibly stays outside the BLR. The minimum electron Lorentz factor, γmin, is constrained from the modeling of these LSP blazars with good soft X-ray data, and in a range from 5 to 160 (with a median value of 55), which plays a key role in jet power estimation. Assuming one-to-one ratio of proton and electron, we find that the jet power for LSP blazars is systematically higher than that of Fanaroff-Riley type II (FR II) radio galaxies. A possible reason for this is that there are some positrons in the jets of these blazars. If this is the case, the jet power will be reduced. Therefore, we propose a mixed composition of e±-p in the jets of these LSP blazars. If we assume that the jet power of LSP blazars is the same as that of FR IIs, we find that it is an electron-positron pair dominated leptonic jet in these blazars, and the number density of electron-positron pairs is several times higher than that of electron-proton pairs, but the jet power is still dominated by protons. For the high-synchrotron-peaked (HSP) BL Lac PKS 1424+240, the SED fitting with the synchrotron self-Compton (SSC) model gave unreasonable fitting parameters (e.g., a very large Doppler factor δ). In this work, we take into account the possible external soft photon field, and then fit the multi-waveband SEDs of blazar PKS 1424+240 with one-zone leptonic jet models in both states. We find the SSC+external-Compton (EC) model can give a better fitting result if the EC process is included. However, the needed energy density of external soft photon field (U_{ext}) is much lower than the typical value. This result is consistent with the results of some other BL Lacs, where the BLR or torus is very weak or disappearing. It means that there is evolution of the energy density of external soft photon field with decreasing of the luminosity of blazars (the flat spectrum radio quasars (FSRQs)-BL Lac: low energy peaked BL Lac (LBL)-intermediate energy peaked BL Lac (IBL)-high energy peaked BL Lac (HBL)). And on this basis, in the chapter 5, we further explore the possible evolution of the external soft photon field of blazars based on the EC process. We employ the one-zone homogeneous leptonic jet model and χ2 procedure to fit simultaneously or quasi-simultaneously multi-waveband SEDs for a sample of blazars with a wide distribution of luminosities. In our model, we set Uext as a free parameter. Studying the energy density of the external photon field in different subclasses of blazars, we find: (1) the Uext of the high luminosity blazar (FSRQs and LBLs) keeps roughly as a constant, which is, however, smaller than that constrained from BLR observations. Assuming IR as the source of soft photons, the Uext is roughly consistent with the torus observational result. This further supports the result that the external soft photon field may originate from torus, and the γ-ray emitting region of these LSP blazars locates outside the BLR. (2) For some IBLs, the EC process may be still needed, but the photon energy density is less than the typical values of the photon energy density of BLR (or dust torus), where the Uext decreases with decreasing of the luminosity. This evolution is consistent with the BLR or torus as directly constrained from the radio-quiet AGN. The final part summarizes the study on the subject, and makes some suggestions for further researches.
In-Space Transportation with Tethers

NASA Technical Reports Server (NTRS)

Lorenzini, Enrico; Estes, Robert D.; Cosmo, Mario L.

1998-01-01

The annual report covers the research conducted on the following topics related to the use of spaceborne tethers for in-space transportation: ProSEDS tether modeling (current collection analyses, influence of a varying tether temperature); proSEDS mission analysis and system dynamics (tether thermal model, thermo-electro-dynamics integrated simulations); proSEDS-tether development and testing (tether requirements, deployment test plan, tether properties testing, deployment tests); and tethers for reboosting the space-based laser (mission analysis, tether system preliminary design, evaluation of attitude constraints).
Development and validation of the Stirling Eating Disorder Scales.

PubMed

Williams, G J; Power, K G; Miller, H R; Freeman, C P; Yellowlees, A; Dowds, T; Walker, M; Parry-Jones, W L

1994-07-01

The development and reliability/validity check of an 80-item, 8-scale measure for use with eating disorder patients is presented. The Stirling Eating Disorder Scales (SEDS) assess anorexic dietary behavior, anorexic dietary cognitions, bulimic dietary behavior, bulimic dietary cognitions, high perceived external control, low assertiveness, low self-esteem, and self-directed hostility. The SEDS were administered to 82 eating disorder patients and 85 controls. Results indicate that the SEDS are acceptable in terms of internal consistency, reliability, group validity, and concurrent validity.
Periodontal biomechanics: finite element simulations of closing stroke and power stroke in equine cheek teeth

PubMed Central

2012-01-01

Background In equine dentistry periodontal diseases, especially periapical inflammation, are frequently occurring problems. Anachoresis is believed to be the most common cause for the development of such disorders. Nevertheless, there is still no substantiated explanation why settlement of pathogen microorganisms occurs in equine periodontal tissues. It is expected that excessive strains and stresses occurring in the periodontal ligament (PDL) during the horse’s chewing cycle might be a predisposing factor. In this study this assumption was examined by finite element (FE) analyses on virtual 3-D models of equine maxillary and mandibular cheek teeth, established on the basis of μCT datasets. Calculations were conducted both under conditions of closing and power stroke. Results Results showed a uniform distribution of low stresses and strain energy density (SED) during closing stroke, whereas during power stroke an occurrence of high stresses and SED could be observed in the PDL near the alveolar crest and in periapical regions. Conclusion The concentration of forces during power stroke in these specific areas of the PDL may cause local tissue necrosis and inflammation and thus establish a suitable environment for the settlement of microorganisms. PMID:22607543
The multiwavelength spectrum of NGC 3115: hot accretion flow properties

NASA Astrophysics Data System (ADS)

Almeida, Ivan; Nemmen, Rodrigo; Wong, Ka-Wah; Wu, Qingwen; Irwin, Jimmy A.

2018-04-01

NGC 3115 is the nearest galaxy hosting a billion solar mass black hole and is also a low-luminosity active galactic nucleus (LLAGN). X-ray observations of this LLAGN are able to spatially resolve the hot gas within the sphere of gravitational influence of the supermassive black hole. These observations make NGC 3115 an important test bed for black hole accretion theory in galactic nuclei since they constrain the outer boundary conditions of the hot accretion flow. We present a compilation of the multiwavelength spectral energy distribution (SED) of the nucleus of NGC 3115 from radio to X-rays. We report the results from modelling the observed SED with radiatively inefficient accretion flow (RIAF) models. The radio emission can be well-explained by synchrotron emission from the RIAF without the need for contribution from a relativistic jet. We obtain a tight constraint on the RIAF density profile, ρ (r) ∝ r^{-0.73 _{-0.02} ^{+0.01}}, implying that mass-loss through subrelativistic outflows from the RIAF is significant. The lower frequency radio observation requires the synchrotron emission from a non-thermal electron population in the RIAF, similarly to Sgr A*.

Economic benefits of safety-engineered sharp devices in Belgium - a budget impact model.

PubMed

Hanmore, Emma; Maclaine, Grant; Garin, Fiona; Alonso, Alexander; Leroy, Nicolas; Ruff, Lewis

2013-11-25

Measures to protect healthcare workers where there is risk of injury or infection from medical sharps became mandatory in the European Union (EU) from May 2013. Our research objective was to estimate the net budget impact of introducing safety-engineered devices (SEDs) for prevention of needlestick injuries (NSIs) in a Belgian hospital. A 5-year incidence-based budget impact model was developed from the hospital inpatient perspective, comparing costs and outcomes with SEDs and prior-used conventional (non-safety) devices. The model accounts for device acquisition costs and costs of NSI management in 4 areas of application where SEDs are currently used: blood collection, infusion, injection and diabetes insulin administration. Model input data were sourced from the Institut National d'Assurance Maladie-Invalidité, published studies, clinical guidelines and market research. Costs are discounted at 3%. For a 420-bed hospital, 100% substitution of conventional devices by SEDs is estimated to decrease the cumulative 5-year incidence of NSIs from 310 to 75, and those associated with exposure to blood-borne viral diseases from 60 to 15. Cost savings from managing fewer NSIs more than offset increased device acquisition costs, yielding estimated 5-year overall savings of €51,710. The direction of these results is robust to a range of sensitivity and model scenario analyses. The model was most sensitive to variation in the acquisition costs of SEDs, rates of NSI associated with conventional devices, and the acquisition costs of conventional devices. NSIs are a significant potential risk with the use of sharp devices. The incidence of NSIs and the costs associated with their management can be reduced through the adoption of safer work practices, including investment in SEDs. For a Belgian hospital, the budget impact model reports that the incremental acquisition costs of SEDs are offset by the savings from fewer NSIs. The availability of more robust data for NSI reduction rates, and broadening the scope of the model to include ancillary measures for hospital conversion to SED usage, outpatient and paramedic device use, and transmission of other blood-borne diseases, would strengthen the model.
Unusual flaring activity in the blazar PKS 1424-418 during 2008-2011

DOE PAGES

Buson, S.; Longo, F.; Larsson, S.; ...

2014-09-01

Context. Blazars are a subset of active galactic nuclei (AGN) with jets that are oriented along our line of sight. Variability and spectral energy distribution (SED) studies are crucial tools for understanding the physical processes responsible for observed AGN emission. Aims. We report peculiar behaviour in the bright γ-ray blazar PKS 1424-418 and use its strong variability to reveal information about the particle acceleration and interactions in the jet. Methods. Correlation analysis of the extensive optical coverage by the ATOM telescope and nearly continuous γ-ray coverage by the Fermi Large Area Telescope is combined with broadband, time-dependent modeling of themore » SED incorporating supplemental information from radio and X-ray observations of this blazar. Results. We analyse in detail four bright phases at optical-GeV energies. These flares of PKS 1424-418 show high correlation between these energy ranges, with the exception of one large optical flare that coincides with relatively low γ-ray activity. Although the optical/ γ-ray behaviour of PKS 1424-418 shows variety, the multiwavelength modeling indicates that these differences can largely be explained by changes in the flux and energy spectrum of the electrons in the jet that are radiating. We find that for all flares the SED is adequately represented by a leptonic model that includes inverse Compton emission from external radiation fields with similar parameters. Conclusions. Detailed studies of individual blazars like PKS 1424-418 during periods of enhanced activity in different wavebands are helping us identify underlying patterns in the physical parameters in this class of AGN.« less
Gamma-ray blazars within the first 2 billion years

DOE PAGES

Ackermann, M.; Ajello, M.; Baldini, L.; ...

2017-02-27

Here, the detection of high-redshift (more » $$z\\,\\gt 3$$) blazars enables the study of the evolution of the most luminous relativistic jets over cosmic time. More importantly, high-redshift blazars tend to host massive black holes and can be used to constrain the space density of heavy black holes in the early universe. Here, we report the first detection with the Fermi-Large Area Telescope of five γ-ray-emitting blazars beyond z = 3.1, more distant than any blazars previously detected in γ-rays. Among these five objects, NVSS J151002+570243 is now the most distant known γ-ray-emitting blazar at z = 4.31. These objects have steeply falling γ-ray spectral energy distributions (SEDs), and those that have been observed in X-rays have a very hard X-ray spectrum, both typical of powerful blazars. Their Compton dominance (ratio of the inverse Compton to synchrotron peak luminosities) is also very large ($$\\gt 20$$). All of these properties place these objects among the most extreme members of the blazar population. Their optical spectra and the modeling of their optical-UV SEDs confirm that these objects harbor massive black holes ($${M}_{\\mathrm{BH}}\\sim {10}^{8-10}\\,{M}_{\\odot }$$). We find that, at $$z\\approx 4$$, the space density of $$\\gt {10}^{9}\\,{M}_{\\odot }$$ black holes hosted in radio-loud and radio-quiet active galactic nuclei are similar, implying that radio-loudness may play a key role in rapid black hole growth in the early universe.« less
A new tool for post-AGB SED classification

NASA Astrophysics Data System (ADS)

Bendjoya, P.; Suarez, O.; Galluccio, L.; Michel, O.

We present the results of an unsupervised classification method applied on a set of 344 spectral energy distributions (SED) of post-AGB stars extracted from the Torun catalogue of Galactic post-AGB stars. This method aims to find a new unbiased method for post-AGB star classification based on the information contained in the IR region of the SED (fluxes, IR excess, colours). We used the data from IRAS and MSX satellites, and from the 2MASS survey. We applied a classification method based on the construction of the dataset of a minimal spanning tree (MST) with the Prim's algorithm. In order to build this tree, different metrics have been tested on both flux and color indices. Our method is able to classify the set of 344 post-AGB stars in 9 distinct groups according to their SEDs.
SNSEDextend: SuperNova Spectral Energy Distributions extrapolation toolkit

NASA Astrophysics Data System (ADS)

Pierel, Justin D. R.; Rodney, Steven A.; Avelino, Arturo; Bianco, Federica; Foley, Ryan J.; Friedman, Andrew; Hicken, Malcolm; Hounsell, Rebekah; Jha, Saurabh W.; Kessler, Richard; Kirshner, Robert; Mandel, Kaisey; Narayan, Gautham; Filippenko, Alexei V.; Scolnic, Daniel; Strolger, Louis-Gregory

2018-05-01

SNSEDextend extrapolates core-collapse and Type Ia Spectral Energy Distributions (SEDs) into the UV and IR for use in simulations and photometric classifications. The user provides a library of existing SED templates (such as those in the authors' SN SED Repository) along with new photometric constraints in the UV and/or NIR wavelength ranges. The software then extends the existing template SEDs so their colors match the input data at all phases. SNSEDextend can also extend the SALT2 spectral time-series model for Type Ia SN for a "first-order" extrapolation of the SALT2 model components, suitable for use in survey simulations and photometric classification tools; as the code does not do a rigorous re-training of the SALT2 model, the results should not be relied on for precision applications such as light curve fitting for cosmology.
LBGs properties from z˜3 to z˜6

NASA Astrophysics Data System (ADS)

de Barros, S.; Schaerer, D.; Stark, D. P.

2011-12-01

We analyse the spectral energy distribution (SED) of U, B, V and i-dropout samples from GOODS-MUSIC and we determine their physical properties, such as stellar age and mass, dust attenuation and star formation rate (SFR). Furthermore, we examine how the strength of Lyα emission can be constrained from broad-band SED fits instead of relying in spectroscopy. We use our SED fitting tool including the effects of nebular emission and we explore different star formation histories (SFHs). We find that SEDs are statistically better fitted with nebular emission and exponentially decreasing star formation. Considering this result, stellar mass and star formation rate (SFR) estimations modify the specific SFR (SFR/M_{⋆}) - redshift relation, in compared to previous studies. Finally, our inferred Lyα properties are in good agreement with the available spectroscopic observations.
Improved heterologous protein production by a tripeptidyl peptidase gene (AosedD) disruptant of the filamentous fungus Aspergillus oryzae.

PubMed

Zhu, Lin; Nemoto, Takeshi; Yoon, Jaewoo; Maruyama, Jun-ichi; Kitamoto, Katsuhiko

2012-01-01

Proteolytic degradation is one of the serious bottlenecks limiting the yields of heterologous protein production by Aspergillus oryzae. In this study, we selected a tripeptidyl peptidase gene AosedD (AO090166000084) as a candidate potentially degrading the heterologous protein, and performed localization analysis of the fusion protein AoSedD-EGFP in A. oryzae. As a result, the AoSedD-EGFP was observed in the septa and cell walls as well as in the culture medium, suggesting that AoSedD is a secretory enzyme. An AosedD disruptant was constructed to investigate an effect of AoSedD on the production level of heterologous proteins and protease activity. Both of the total protease and tripeptidyl peptidase activities in the culture medium of the AosedD disruptant were decreased as compared to those of the control strain. The maximum yields of recombinant bovine chymosin (CHY) and human lysozyme (HLY) produced by the AosedD disruptants showed approximately 2.9- and 1.7-fold increases, respectively, as compared to their control strains. These results suggest that AoSedD is one of the major proteases involved in the proteolytic degradation of recombinant proteins in A. oryzae.
Estimating Spectra from Photometry

NASA Astrophysics Data System (ADS)

Kalmbach, J. Bryce; Connolly, Andrew J.

2017-12-01

Measuring the physical properties of galaxies such as redshift frequently requires the use of spectral energy distributions (SEDs). SED template sets are, however, often small in number and cover limited portions of photometric color space. Here we present a new method to estimate SEDs as a function of color from a small training set of template SEDs. We first cover the mathematical background behind the technique before demonstrating our ability to reconstruct spectra based upon colors and then compare our results to other common interpolation and extrapolation methods. When the photometric filters and spectra overlap, we show that the error in the estimated spectra is reduced by more than 65% compared to the more commonly used techniques. We also show an expansion of the method to wavelengths beyond the range of the photometric filters. Finally, we demonstrate the usefulness of our technique by generating 50 additional SED templates from an original set of 10 and by applying the new set to photometric redshift estimation. We are able to reduce the photometric redshifts standard deviation by at least 22.0% and the outlier rejected bias by over 86.2% compared to original set for z ≤ 3.
Comparing cosmological hydrodynamic simulations with observations of high- redshift galaxy formation

NASA Astrophysics Data System (ADS)

Finlator, Kristian Markwart

We use cosmological hydrodynamic simulations to study the impact of outflows and radiative feedback on high-redshift galaxies. For outflows, we consider simulations that assume (i) no winds, (ii) a "constant-wind" model in which the mass-loading factor and outflow speed are constant, and (iii) "momentum-driven" winds in which both parameters vary smoothly with mass. In order to treat radiative feedback, we develop a moment-based radiative transfer technique that operates in both post-processing and coupled radiative hydrodynamic modes. We first ask how outflows impact the broadband spectral energy distributions (SEDs) of six observed reionization-epoch galaxies. Simulations reproduce five regardless of the outflow prescription, while the sixth suggests an unusually bursty star formation history. We conclude that (i) simulations broadly account for available constraints on reionization-epoch galaxies, (ii) individual SEDs do not constrain outflows, and (iii) SED comparisons efficiently isolate objects that challenge simulations. We next study how outflows impact the galaxy mass metallicity relation (MZR). Momentum-driven outflows uniquely reproduce observations at z = 2. In this scenario, galaxies obey two equilibria: (i) The rate at which a galaxy processes gas into stars and outflows tracks its inflow rate; and (ii) The gas enrichment rate owing to star formation balances the dilution rate owing to inflows. Combining these conditions indicates that the MZR is dominated by the (instantaneous) variation of outflows with mass, with more-massive galaxies driving less gas into outflows per unit stellar mass formed. Turning to radiative feedback, we use post-processing simulations to study the topology of reionization. Reionization begins in overdensities and then "leaks" directly into voids, with filaments reionizing last owing to their high density and low emissivity. This result conflicts with previous findings that voids ionize last. We argue that it owes to the uniqely-biased emissivity field produced by our star formation prescriptions, which have previously been shown to reproduce numerous post-reionization constraints. Finally, preliminary results from coupled radiative hydrodynamic simulations indicate that reionization suppresses the star formation rate density by at most 10-20% by z = 5. This is much less than previous estimates, which we attribute to our unique reionization topology although confirmation will have to await more detailed modeling.
A quantitative study of peculiarities in galaxy morphology

NASA Astrophysics Data System (ADS)

Wu, Katherine Liang-Kai

I have developed a refined version of the asymmetry parameter first presented by Abraham et al. (1996). Coupled with a simple concentration index, this pair of indices, AW-CW, is compared to Abraham et al.'s log(AA)-log(C A) algorithm. These indices are then applied to a large sample of galaxies in the Hubble Deep Field with photometric redshifts from Connolly (1999). This allows investigation of trends at redshifts which have been largely inaccessible until now. The final sample consists of ~350 objects detected by the AW-CW algorithms with first-moment radii, r1 >= 0'.2 (corresponding to F814WAB ~ 26). The distribution of objects in the AW- CW plane is found to change with redshift. The region of the AW - CW plane populated by objects out to z ~ 1.2 is roughly constant. Accounting for bandpass shifting effects, this region resembles that populated by local bright galaxies (Frei et al. 1996) cosmologically simulated at z = 0.8. Beyond z ~ 1.2, the distribution of galaxies undergoes a significant change. Highly concentrated objects disappear from the AW-C W plane, while high asymmetry objects appear. The high concentration objects below z ~ 1.2 all have early-type morphologies. Very low resolution SEDs of these galaxies created using colors from Williams et al. (1996) are used to calculate the expected appearance of these objects at higher redshifts (z = 1.5 and 2.3). Assuming their luminosities and SEDs have not changed, one-third of the z ~ 0.8 objects would be undetected at z = 1.5, and 97% would disappear by z = 2.3. Any true drop in the number density of these objects would be completely masked by such strong selection effects. An increase in the number and degree of asymmetric objects is also seen beyond z ~ 1.2. Many of these objects exhibit multiple condensations, consistent with merging. Though the shifting of the ultraviolet galaxy spectrum into the F814W-band may be partially responsible, the majority of the increase in both number and degree of asymmetry appears to reflect a genuinely higher number density of asymmetric objects at earlier epochs. AW and CW are shown to be useful tools for exploring galaxy morphology over a wide range of redshifts. Future refinements combined with better SEDs and evolutionary models will undoubtedly reveal valuable insight into galaxy evolution.
Dynamics of the High-latitude Ionospheric Irregularities During the 2015 St. Patrick's Day Storm

NASA Astrophysics Data System (ADS)

Cherniak, I.; Zakharenkova, I.; Redmon, R. J.; Andrzej, K.

2015-12-01

We presents results on the study of the high-latitude ionospheric irregularities observed in worldwide GPS data during the St. Patrick's Day geomagnetic storm (March 17, 2015). Multi-site GPS observations from more than 2500 ground-based GPS stations were used to analyze the dynamics of the ionospheric irregularities in the Northern and Southern Hemispheres. The most intense ionospheric irregularities lasted for more than 24 hours starting at 07 UT of March 17. This period correlates well with an increase of the auroral Hemispheric Power index. We find hemispheric asymmetries in the intensity and spatial structure of the ionospheric irregularities. Over North America the ionospheric irregularities zone expanded equatorward below ~45°N geographic latitude. Additionally, the strong mid and high latitude GPS phase irregularities in the auroral oval were found to be related to the formation of storm enhanced density, polar tongues of ionization and deepening of the main ionospheric trough through upper atmosphere ionization by energetic particle precipitations. Significant increases in the intensity of the irregularities within the polar cap region of both hemispheres were associated with the formation and evolution of the SED/TOI structures and polar patches.
GOSSIP: SED fitting code

NASA Astrophysics Data System (ADS)

Franzetti, Paolo; Scodeggio, Marco

2012-10-01

GOSSIP fits the electro-magnetic emission of an object (the SED, Spectral Energy Distribution) against synthetic models to find the simulated one that best reproduces the observed data. It builds-up the observed SED of an object (or a large sample of objects) combining magnitudes in different bands and eventually a spectrum; then it performs a chi-square minimization fitting procedure versus a set of synthetic models. The fitting results are used to estimate a number of physical parameters like the Star Formation History, absolute magnitudes, stellar mass and their Probability Distribution Functions.
ISO LWS Spectroscopy of M82: A Unified Evolutionary Model

DTIC Science & Technology

1999-01-01

ences in the weak [N II] 122 and [O I] 145 km lines. Our continuum measurements, however, go from being 30% higher to 10% lower than the KAO values...due to the hardness of the input SED. The Leitherer & Heckman (1995) SEDs are signiÐcantly harder than the SED Spino- glio & Malkan (1992) used. The ...Spinoglio & Malkan (1992) PDR parameters were also di†erent n \\ 104h5(G0 \\ 104,cm~3), but this can be mainly attributed to the newer PDR models of
The Nature of Faint Spitzer-selected Dust-obscured Galaxies

NASA Astrophysics Data System (ADS)

Pope, Alexandra; Bussmann, R. Shane; Dey, Arjun; Meger, Nicole; Alexander, David M.; Brodwin, Mark; Chary, Ranga-Ram; Dickinson, Mark E.; Frayer, David T.; Greve, Thomas R.; Huynh, Minh; Lin, Lihwai; Morrison, Glenn; Scott, Douglas; Yan, Chi-Hung

2008-12-01

We use deep far-IR, submillimeter, radio, and X-ray imaging and mid-IR spectroscopy to explore the nature of a sample of Spitzer-selected dust-obscured galaxies (DOGs) in GOODS-N. A sample of 79 galaxies satisfy the criteria R - [ 24] > 14 (Vega) down to S24 > 100 μJy (median flux density S24 = 180 μJy). Twelve of these galaxies have IRS spectra available, which we use to measure redshifts and classify these objects as being dominated by star formation or active galactic nucleus (AGN) activity in the mid-IR. The IRS spectra and Spitzer photometric redshifts confirm that the DOGs lie in a tight redshift distribution around z ~ 2. Based on mid-IR colors, 80% of DOGs are likely dominated by star formation; the stacked X-ray emission from this subsample of DOGs is also consistent with star formation. Since only a small number of DOGs are individually detected at far-IR and submillimeter wavelengths, we use a stacking analysis to determine the average flux from these objects and plot a composite IR (8-1000 μm) spectral energy distribution (SED). The average luminosity of these star-forming DOGs is LIR ~ 1 × 1012 L⊙. We compare the average star-forming DOG to the average bright (S850 > 5 mJy) submillimeter galaxy (SMG); the S24 > 100 μJy DOGs are 3 times more numerous but 8 times less luminous in the IR. The far-IR SED shape of DOGs is similar to that of SMGs (average dust temperature of around 30 K), but DOGs have a higher mid-IR-to-far-IR flux ratio. The average star formation-dominated DOG has a star formation rate of 200 M⊙ yr -1, which, given their space density, amounts to a contribution of 0.01 M⊙ yr-1 Mpc-3 (or 5%-10%) to the star formation rate density at z ~ 2.
A Synthesis Of Cosmic X-ray And Infrared Background

NASA Astrophysics Data System (ADS)

Shi, Yong; Helou, G.; Armus, L.; Stierwalt, S.

2012-01-01

We present a synthesis model of cosmic IR and X-ray background, with the goal to derive a complete census of cosmic evolution of star formation (SF) and black-hole (BH) growth by complementing advantages of X-ray and IR surveys to each other. By assuming that individual galaxies are experiencing both SF and BH accretion, our model decomposes the total IR LF into SF and BH components while taking into account the luminosity-dependent SED and its dispersion of the SF component, and the extinction-dependent SED of the BH component. The best-fit parameters are derived by fitting to the number counts and redshift distributions at X-ray including both hard and soft bands, and mid-IR to submm bands including IRAS, Spitzer, Herschel, SCUBA, Aztec and MAMBO. Based on the fit result, our models provide a series of predictions on galaxy evolution and black-hole growth. For evolution of infrared galaxies, the model predicts that the total infrared luminosity function is best described through evolution in both luminosity and density. For evolution of AGN populations, the model predicts that the evolution of X-ray LF also shows luminosity and density dependent, that the type-1/type-2 AGN fraction is a function of both luminosity and redshift, and that the Compton-thick AGN number density evolves strongly with redshift, contributing about 20% to the total cosmic BH growth. For BH growth in IR galaxies, the model predicts that the majority of BH growth at z>1 occurs in infrared luminous galaxies and the AGN fraction as a function of IR survey is a strong function of the survey depth, ranging from >50% at bright end to below 10% at faint end. We also evaluates various AGN selection techniques at X-ray and IR wavelengths and offer predictions for future missions at X-ray and IR.
Longitudinal Health Consequences of Socioeconomic Disadvantage: Examining Perceived Discrimination as a Mediator

PubMed Central

Fuller-Rowell, Thomas E.; Curtis, David S.; Chae, David H.; Ryff, Carol D.

2018-01-01

Objective Foundational theoretical perspectives suggest that socioeconomic disadvantage (SED) increases an individual’s risk of being exposed to unfair treatment or discrimination. However, little empirical attention has been given to the role of perceived discrimination in the SED-health gradient. Addressing this knowledge gap, the current study examined the mediating role of discrimination in the longitudinal association between SED and self-rated health. Methods Participants in the Midlife in the United States (MIDUS) study were followed over three waves covering a 17–19 year period (N = 6286; 53% female; 91% White; Mean Age at baseline = 47 years, SD = 13). SED was assessed from education, occupational prestige, income, and assets; self-rated health was measured at baseline and follow-up assessments. Two measures of discrimination—perceived inequality in work and everyday discrimination—were considered as mediators. Results Both measures of discrimination emerged as important explanatory variables in the link between SED and health. SED at the baseline assessment was associated with changes in self-rated health over the 17–19 year period (B = −.15, p < .001). Measures of discrimination partially mediated this longitudinal association, explaining 22% of the total effect. Exposure to discrimination and its health consequences were also more pronounced at younger ages. Conclusion Additional research is needed to replicate the findings of this study using objective health measures and to examine possible interventions. Challenging the ideologies and practices that underlie social class-related discrimination, or mitigating its harmful consequences, will both be important approaches to consider. PMID:29698020
Sustained rise in triacylglycerol synthesis and increased epididymal fat mass when rats cease voluntary wheel running

PubMed Central

Kump, David S; Booth, Frank W

2005-01-01

Four-week-old, Fischer–Brown Norway F1-generation male rats were given access to voluntary running wheels for 21 days, and then the wheels were locked for 5 (WL5), 10 (WL10), 29 (WL29), or 53 (WL53) hours. Two other groups (SED5 and SED10) had no access to voluntary running wheels and were killed at the same time as WL5 and WL10, respectively. Absolute and relative epididymal fat mass, mean cell volume, and amount of lipid per cell increased in WL53 relative to all other groups, with no change in cell number. C/EBPα protein levels in epididymal fat were 30% greater in SED5 than in WL5. The rate of triacylglycerol synthesis in epididymal fat was 4.2-fold greater in SED5 than in WL5, increased 14-fold between WLS and WL10, and was 79% lower in SED10 than in WL10. Triacylglycerol synthesis remained at this elevated level (at least 3.5-fold greater than SED5) through WL53. Thus, the rapid increase in epididymal fat mass with the cessation of voluntary wheel running is associated with a prolonged overshoot in epididymal fat triacylglycerol synthesis. Moreover, rats without running wheels had a 9.4% lower body mass after 21 days than those with running wheels. The individual mass of seven different muscles from the hindlimb, upper forelimb, and back were each lower in animals without running wheels, suggesting that physical activity in rapidly growing rats may be requisite for optimal muscle development. PMID:15774517
Strength of Rocks Affected by Deformation Enhanced Grain Growth

NASA Astrophysics Data System (ADS)

Kellermann Slotemaker, A.; de Bresser, H.; Spiers, C.

2005-12-01

One way of looking into the possibility of long-term strength changes in the lithosphere is to study transient effects resulting from modifications of the microstructure of rocks. It is generally accepted that mechanical weakening may occur due to progressive grain size refinement resulting from dynamic recrystallization. A decrease in grain size may induce a switch from creep controlled by grain size insensitive dislocation mechanisms to creep governed by grain size sensitive (GSS) mechanisms involving diffusion and grain boundary sliding processes. This switch forms a well-known scenario to explain localization in the lithosphere. However, fine-grained rocks in localized deformation zones are prone to grain coarsening due to surface energy driven grain boundary migration (SED-GBM). This might harden the rock, affecting its role in localizing strain in the long term. The question has arisen if grain growth by SED-GBM in a rock deforming in the GSS creep field can be significantly affected by strain. The broad aim of this study is to shed more light onto this. We have experimentally investigated the microstructural and strength evolution of fine-grained (~0.6 μm) synthetic forsterite and Fe-bearing olivine aggregates that coarsen in grain size while deforming by GSS creep at elevated pressure (600 MPa) and temperature (850-1000 °C). The materials were prepared by `sol-gel' method and contained 0.3-0.5 wt% water and 5-10 vol% enstatite. We performed i) static heat treatment tests of various time durations involving hot isostatic pressing (HIP), and ii) heat treatment tests starting with HIP and continuing with deformation up to 45% axial strain at strain rates in the range 4x10-7 - 1x10-4 s-1. Microstructures were characterized by analyzing full grain size distributions and textures using SEM/EBSD. In addition to the experiments, we studied microstructural evolution in simple two-dimensional numerical models, combining deformation and SED-GBM by means of the modeling package ELLE. Synthetic olivine samples that were heat treated without straining showed only minor grain growth. Presumably, the second phase (enstatite) and/or porosity remaining in the starting material after densification slowed down or inhibited SED-GBM in the static situation. In contrast, samples heat treated and deformed for time durations similar to those of the static tests demonstrated, at identical temperature, an increase in grain size with increasing strain up to a value twice that of the static counterpart. This grain coarsening was associated with continuous hardening of the material, witnessed by the stress-strain curves. A random lattice preferred orientation combined with a low stress sensitivity (n~2) suggested dominant GSS creep controlled by grain boundary sliding. A dynamic grain growth model involving an increase in the fraction of non-hexagonal grains, related to grain neighbor switching, appears applicable to the observed grain growth that is held responsible for the hardening. The ELLE numerical modeling demonstrated that a combination of SED-GBM and geometrical deformation of a 2D grain aggregate can indeed result in enhanced grain growth compared to static grain growth tests. The fraction of non-hexagonal grains was found to remain more or less constant during static grain growth but increased during deformation. We suggest that the application of the dynamic grain growth model to the long-term microstructural evolution of fine-grained lithospheric shear zones can further improve our understanding of the transient or permanent character of strain localizations and related rheological behavior.
Five thousand years of tropical lake sediment DNA records from Benin

NASA Astrophysics Data System (ADS)

Bremond, L.; Favier, C.; Ficetola, G. F.; Tossou, M. G.; Akouégninou, A.; Gielly, L.; Giguet-Covex, C.; Oslisly, R.; Salzmann, U.

2017-08-01

Until now, sedimentary DNA (sedDNA) studies have only focused on cold and temperate regions were DNA is relatively well preserved. Consequently, the tropics, where vegetation is hyperdiverse and natural archives are rare, have been neglected and deserve attention. In this study, we used next-generation sequencing to barcode sedDNA from Lake Sele, localized in the tropical lowlands of Benin (Africa), and compared the taxonomic diversity detected by DNA analyses with pollen assemblages. Plant sedDNA was successfully amplified from 33 of the 34 successfully extracted samples. In total, 43 taxa were identified along the 5000 years spanned by the sediment: 22 taxa were identified at the family level and 21 at the genus level. The plant diversity recovered through sedDNA from Lake Sele showed a specific local signal and limited overlapping with pollen. Introduced plants, grown and cultivated close to the water, such as sweet potato, were also well recorded by sedDNA. It appears, therefore, to be a promising approach to studying past diversity in tropical regions, and could help in tracking the introduction and history of agriculture. This is the first time this method has been used in the field of domestication and dissemination of several specific crops, and the results are very encouraging.
The SED Machine: a dedicated transient IFU spectrograph

NASA Astrophysics Data System (ADS)

Ben-Ami, Sagi; Konidaris, Nick; Quimby, Robert; Davis, Jack T.; Ngeow, Chow Choong; Ritter, Andreas; Rudy, Alexander

2012-09-01

The Spectral Energy Distribution (SED) Machine is an Integral Field Unit (IFU) spectrograph designed specifically to classify transients. It is comprised of two subsystems. A lenselet based IFU, with a 26" × 26" Field of View (FoV) and ˜ 0.75" spaxels feeds a constant resolution (R˜100) triple-prism. The dispersed rays are than imaged onto an off-the-shelf CCD detector. The second subsystem, the Rainbow Camera (RC), is a 4-band seeing-limited imager with a 12.5' × 12.5' FoV around the IFU that will allow real time spectrophotometric calibrations with a ˜ 5% accuracy. Data from both subsystems will be processed in real time using a dedicated reduction pipeline. The SED Machine will be mounted on the Palomar 60-inch robotic telescope (P60), covers a wavelength range of 370 - 920nm at high throughput and will classify transients from on-going and future surveys at a high rate. This will provide good statistics for common types of transients, and a better ability to discover and study rare and exotic ones. We present the science cases, optical design, and data reduction strategy of the SED Machine. The SED machine is currently being constructed at the Calofornia Institute of Technology, and will be comissioned on the spring of 2013.

Food intake and appetite following school-based high-intensity interval training in 9-11-year-old children.

PubMed

Morris, Anna; Cramb, Robert; Dodd-Reynolds, Caroline J

2018-02-01

Using a randomised cross-over design, free-living lunch intake and subjective appetite were examined in 10 children (9.8 ± 0.6 years) following high-intensity interval training (HIIT) versus a control sedentary (SED) period, within a school setting. The 22-min HIIT took place during a regular PE lesson and consisted of two rounds of 4 × 30 s sprints. Foods were offered at a regular school lunch immediately following HIIT and SED and were matched between conditions. All food was covertly weighed before and after the meal. Hunger, fullness and prospective consumption were reported immediately before and after HIIT/SED, using visual analogue scales. Heart rate was higher during HIIT than SED (159.3 ± 23.1 vs. 76.9 ± 2.2 bpm, P < 0.05). Lunch energy intake was not different (P = 0.52) following HIIT, compared to SED (2.06 ± 0.35 vs. 2.09 ± 0.29 MJ, respectively). There were no significant differences in macronutrient intake or subjective appetite (P > 0.05). Results suggest that HIIT can be implemented in a PE lesson immediately before lunch, without causing a compensatory increase in food consumption.
A Complete Library of Infrared Spectral Energy Distributions for z=0 Galaxies

NASA Astrophysics Data System (ADS)

Sandstrom, Karin

CONTEXT: Half of the light emitted by galaxies is starlight absorbed and reprocessed into the infrared by dust. The spectral energy distribution (SED) of this IR emission encodes information on the mass and properties of the dust, the radiation field heating it, and the bolometric luminosity of the region. This makes IR emission a main tool to estimate star formation rates (SFRs) and to trace the distribution of the interstellar medium (ISM) in galaxies. The dust itself also plays key roles in the physics of star formation, and thereby galaxy evolution. This critical information on dust and its dependence on environment can only be reliably measured when we have observations with full wavelength coverage of the IR SED that resolve galaxies. With no new IR imaging missions on the horizon, the remarkably thorough census conducted by Herschel, Spitzer, and WISE of the nearby (D < 50 Mpc) galaxy population is the definitive resource on dust at z=0 for the foreseeable future. Such observations allow us to understand the behavior of the IR SED and so inform observations from the major new facilities ALMA and JWST, which have amazing sensitivity and resolution but limited wavelength coverage. OBJECTIVES: We will create a library of matched resolution, uniformly processed IR SEDs for all 532 local galaxies with resolved mapping in the Herschel, Spitzer, and WISE archives. We will associate the SED measurements with rich "value added" data, including fits of physical models to the IR SED (yielding small grain fractions, temperature, and dust masses), host galaxy properties (e.g., stellar mass, SFR, morphology, inclination), and local conditions in the galaxy (SFR and stellar surface density, ISM gas mass and metallicity where available). The library will be created for a range of spatial and angular scales and served through IRSA/MAST, providing a major high level legacy resource that will be useful to a wide community. We will exploit this database to address three major questions: (1) What powers the dust emission from galaxies and how does dust emission relate to the star formation rate? (2) How are dust and gas related across the galaxy population and how can dust emission best be used to trace gas? and (3) How does the dust grain population vary in response to local environment across galaxies? METHODS: We will use established techniques to uniformly process the archival data, fit models to the spectral energy distributions, match the data in resolution. These have been successfully deployed on similar data by individual teams (including us), but we will apply them to an order of magnitude larger sample. PERCEIVED SIGNIFICANCE: Dust is a main mediator of cloud and star formation, and thus galaxy evolution. Therefore, the properties and evolution of dust in galaxies is directly relevant to key NASA science goals to "Discover how the universe works, explore how it began and evolved, and search for life on planets around other stars." These are also essential tools to understand "How did we get here?" In practical terms, the database that we propose to create would be a major resource for many scientists: a tool to understand the physics of dust and the ISM for those studying local galaxies and a major aid to interpret monochromatic observations of high-z galaxies and galaxy surveys. This should have a large impact in the ALMA and (soon) JWST communities.
Daily physical activity enhances reactivity to insulin in skeletal muscle arterioles of hyperphagic Otsuka Long-Evans Tokushima Fatty rats.

PubMed

Mikus, Catherine R; Rector, R Scott; Arce-Esquivel, Arturo A; Libla, Jessica L; Booth, Frank W; Ibdah, Jamal A; Laughlin, M Harold; Thyfault, John P

2010-10-01

Insulin-mediated glucose disposal is dependent on the vasodilator effects of insulin. In type 2 diabetes, insulin-stimulated vasodilation is impaired as a result of an imbalance in NO and ET-1 production. We tested the hypothesis that chronic voluntary wheel running (RUN) prevents impairments in insulin-stimulated vasodilation associated with obesity and type 2 diabetes independent of the effects of RUN on adiposity by randomizing Otsuka Long Evans Tokushima Fatty (OLETF) rats, a model of hyperphagia-induced obesity and type 2 diabetes, to 1) RUN, 2) caloric restriction (CR; diet adjusted to match body weights of RUN group), or 3) sedentary control (SED) groups (n = 8/group) at 4 wk. At 40 wk, NO- and ET-1-mediated vasoreactivity to insulin (1-1,000 μIU/ml) was assessed in the presence of a nonselective ET-1 receptor blocker (tezosentan) or a NO synthase (NOS) inhibitor [N(G)-nitro-L-arginine methyl ester (L-NAME)], respectively, in second-order arterioles isolated from the white portion of the gastrocnemius muscle. Body weight, fasting plasma glucose, and hemoglobin A1c were lower in RUN and CR than SED (P < 0.05); however, the glucose area under the curve (AUC) following the intraperitoneal glucose tolerance test was lower only in the RUN group (P < 0.05). Vasodilator responses to all doses of insulin were greater in RUN than SED or CR in the presence of a tezosentan (P < 0.05), but group differences in vasoreactivity to insulin with coadministration of L-NAME were not observed. We conclude daily wheel running prevents obesity and type 2 diabetes-associated declines in insulin-stimulated vasodilation in skeletal muscle arterioles through mechanisms that appear to be NO mediated and independent of attenuating excess adiposity in hyperphagic rats.
Preparation of zein nanoparticles by using solution-enhanced dispersion with supercritical CO2 and elucidation with computational fluid dynamics.

PubMed

Li, Sining; Zhao, Yaping

2017-01-01

Nanoparticles have attracted more and more attention in the medicinal field. Zein is a biomacromolecule and can be used as a carrier for delivering active ingredients to prepare controlled release drugs. In this article, we presented the preparation of zein nanoparticles by solution-enhanced dispersion by supercritical CO 2 (SEDS) approach. Scanning electron microscopy and transmission electron microscopy were applied to characterize the size and morphology of the obtained particles. The nozzle structure and the CO 2 flow rate greatly affected the morphology and the size of the particles. The size of zein was able to be reduced to 50-350 nm according to the different conditions. The morphologies of the resultant zein were either sphere or the filament network consisted of nanoparticles. The influence of the nozzle structure and the CO 2 flow rate on the velocity field was elucidated by using computational fluid dynamics. The nozzle structure and the CO 2 flow rate greatly affected the distribution of the velocity field. However, a similar velocity field could also be obtained when the nozzle structure or the CO 2 flow rate, or both were different. Therefore, the influence of the nozzle structure and the CO 2 flow rate on the size and morphology of the particles, can boil down to the velocity field. The results demonstrated that the velocity field can be a potential criterion for producing nanoparticles with controllable morphology and size, which is useful to scale-up the SEDS process.
Identifications of Four Integral Sources in the Galactic Plane via CHANDRA Localizations

NASA Technical Reports Server (NTRS)

Tomsick, John A.; Chaty, Sylvain; Rodriquez, Jerome; Foschini, Luigi; Walter, Roland; Kaaret, Philip

2006-01-01

Hard X-ray imaging of the Galactic plane by the INTEGRAL satellite is uncovering large numbers of 20-100 keV "IGR" sources. We present results from Chandra, INTEGRAL, optical, and IR observations of four IGR sources: three sources in the Norma region of the Galaxy(1GR J16195-4945,IGR J16207-5129, and IGR J16167-4957) and one that is closer to the Galactic center (IGR 5171 95-4100). In all four cases, one relatively bright Chandra source is seen in the INTEGRAL error circle, and these are likely to be the soft X-ray counterparts of the IGR sources. They have hard 0.3-10 keV spectra with power-law photon indices of Gamma = 0.5-1.1. While many previously studied IGR sources show high column densities (NH approx. 10(exp 23)-10(exp 24)/sq cm), only IGR J16195-4945 has a column density that could be as high as 10(exp 23)/sq cm. Using optical and IR sky survey catalogs and our own photometry, we have obtained identifications for all four sources. The J-band magnitudes are in the range 14.9-10.4, and we have used the optical/IR spectral energy distributions (SEDs) to constrain the nature of the sources. Blackbody components with temperature lower limits of >9400 K for IGR J16195-4945 and >18,000 K for IGR J16207-5129 indicate that these are very likely high-mass X-ray binaries (HMXBs). However, for IGR 516167-4957 and IGR J17195-4100, low extinction and the SEDs indicate later spectral types for the putative companions, suggesting that these are not HMXBs.
The Hi-GAL compact source catalogue - I. The physical properties of the clumps in the inner Galaxy (-71.0° < ℓ < 67.0°)

NASA Astrophysics Data System (ADS)

Elia, Davide; Molinari, S.; Schisano, E.; Pestalozzi, M.; Pezzuto, S.; Merello, M.; Noriega-Crespo, A.; Moore, T. J. T.; Russeil, D.; Mottram, J. C.; Paladini, R.; Strafella, F.; Benedettini, M.; Bernard, J. P.; Di Giorgio, A.; Eden, D. J.; Fukui, Y.; Plume, R.; Bally, J.; Martin, P. G.; Ragan, S. E.; Jaffa, S. E.; Motte, F.; Olmi, L.; Schneider, N.; Testi, L.; Wyrowski, F.; Zavagno, A.; Calzoletti, L.; Faustini, F.; Natoli, P.; Palmeirim, P.; Piacentini, F.; Piazzo, L.; Pilbratt, G. L.; Polychroni, D.; Baldeschi, A.; Beltrán, M. T.; Billot, N.; Cambrésy, L.; Cesaroni, R.; García-Lario, P.; Hoare, M. G.; Huang, M.; Joncas, G.; Liu, S. J.; Maiolo, B. M. T.; Marsh, K. A.; Maruccia, Y.; Mège, P.; Peretto, N.; Rygl, K. L. J.; Schilke, P.; Thompson, M. A.; Traficante, A.; Umana, G.; Veneziani, M.; Ward-Thompson, D.; Whitworth, A. P.; Arab, H.; Bandieramonte, M.; Becciani, U.; Brescia, M.; Buemi, C.; Bufano, F.; Butora, R.; Cavuoti, S.; Costa, A.; Fiorellino, E.; Hajnal, A.; Hayakawa, T.; Kacsuk, P.; Leto, P.; Li Causi, G.; Marchili, N.; Martinavarro-Armengol, S.; Mercurio, A.; Molinaro, M.; Riccio, G.; Sano, H.; Sciacca, E.; Tachihara, K.; Torii, K.; Trigilio, C.; Vitello, F.; Yamamoto, H.

2017-10-01

Hi-GAL (Herschel InfraRed Galactic Plane Survey) is a large-scale survey of the Galactic plane, performed with Herschel in five infrared continuum bands between 70 and 500 μm. We present a band-merged catalogue of spatially matched sources and their properties derived from fits to the spectral energy distributions (SEDs) and heliocentric distances, based on the photometric catalogues presented in Molinari et al., covering the portion of Galactic plane -71.0° < ℓ < 67.0°. The band-merged catalogue contains 100 922 sources with a regular SED, 24 584 of which show a 70-μm counterpart and are thus considered protostellar, while the remainder are considered starless. Thanks to this huge number of sources, we are able to carry out a preliminary analysis of early stages of star formation, identifying the conditions that characterize different evolutionary phases on a statistically significant basis. We calculate surface densities to investigate the gravitational stability of clumps and their potential to form massive stars. We also explore evolutionary status metrics such as the dust temperature, luminosity and bolometric temperature, finding that these are higher in protostellar sources compared to pre-stellar ones. The surface density of sources follows an increasing trend as they evolve from pre-stellar to protostellar, but then it is found to decrease again in the majority of the most evolved clumps. Finally, we study the physical parameters of sources with respect to Galactic longitude and the association with spiral arms, finding only minor or no differences between the average evolutionary status of sources in the fourth and first Galactic quadrants, or between 'on-arm' and 'interarm' positions.
A Search for H I Lyα Counterparts to Ultrafast X-Ray Outflows

NASA Astrophysics Data System (ADS)

Kriss, Gerard A.; Lee, Julia C.; Danehkar, Ashkbiz

2018-06-01

Prompted by the H I Lyα absorption associated with the X-ray ultrafast outflow at ‑17,300 km s‑1 in the quasar PG 1211+143, we have searched archival UV spectra at the expected locations of H I Lyα absorption for a large sample of ultrafast outflows identified in XMM-Newton and Suzaku observations. Sixteen of the X-ray outflows have predicted H I Lyα wavelengths falling within the bandpass of spectra from either the Far Ultraviolet Spectroscopic Explorer or the Hubble Space Telescope, although none of the archival observations were simultaneous with the X-ray observations in which ultrafast X-ray outflows (UFOs) were detected. In our spectra broad features with FWHM of 1000 km s‑1 have 2σ upper limits on the H I column density of generally ≲2 × 1013 cm‑2. Using grids of photoionization models covering a broad range of spectral energy distributions (SEDs), we find that producing Fe XXVI Lyα X-ray absorption with equivalent widths >30 eV and associated H I Lyα absorption with {N}{{H}{{I}}}< 2× {10}13 {cm}}-2 requires total absorbing column densities {N}{{H}}> 5× {10}22 {cm}}-2 and ionization parameters log ξ ≳ 3.7. Nevertheless, a wide range of SEDs would predict observable H I Lyα absorption if ionization parameters are only slightly below peak ionization fractions for Fe XXV and Fe XXVI. The lack of Lyα features in the archival UV spectra indicates that the UFOs have very high ionization parameters, that they have very hard UV-ionizing spectra, or that they were not present at the time of the UV spectral observations owing to variability.
Composite Spectral Energy Distributions and Infrared-Optical Colors of Type 1 and Type 2 Quasars

NASA Astrophysics Data System (ADS)

Hickox, Ryan C.; Myers, Adam D.; Greene, Jenny E.; Hainline, Kevin N.; Zakamska, Nadia L.; DiPompeo, Michael A.

2017-11-01

We present observed mid-infrared and optical colors and composite spectral energy distributions (SEDs) of type 1 (broad-line) and 2 (narrow-line) quasars selected from Sloan Digital Sky Survey (SDSS) spectroscopy. A significant fraction of powerful quasars are obscured by dust and are difficult to detect in optical photometric or spectroscopic surveys. However, these may be more easily identified on the basis of mid-infrared (MIR) colors and SEDs. Using samples of SDSS type 1 and 2 matched in redshift and [O III] luminosity, we produce composite rest-frame 0.2-15 μm SEDs based on SDSS, UKIDSS, and Wide-field Infrared Survey Explorer photometry and perform model fits using simple galaxy and quasar SED templates. The SEDs of type 1 and 2 quasars are remarkably similar, with the differences explained primarily by the extinction of the quasar component in the type 2 systems. For both types of quasar, the flux of the active galactic nucleus (AGN) relative to the host galaxy increases with AGN luminosity ({L}[{{O}{{III}}]}) and redder observed MIR color, but we find only weak dependencies of the composite SEDs on mechanical jet power as determined through radio luminosity. We conclude that luminous quasars can be effectively selected using simple MIR color criteria similar to those identified previously ({{W}}1{--}{{W}}2> 0.7; Vega), although these criteria miss many heavily obscured objects. Obscured quasars can be further identified based on optical-IR colors (for example, (u{--}{{W}}3 [{AB}])> 1.4({{W}}1{--}{{W}}2 [{Vega}])+3.2). These results illustrate the power of large statistical studies of obscured quasars selected on the basis of MIR and optical photometry.
Perceived Exertion during Exercise is Associated with Children's Energy Intake

PubMed Central

Fearnbach, S. Nicole; Masterson, Travis D.; Schlechter, Haley A.; Loken, Eric; Downs, Danielle S.; Thivel, David; Keller, Kathleen L.

2016-01-01

PURPOSE To examine the individual-level factors that predict energy intake (EI) following imposed exercise (EX) and sedentary time (SED) in children. METHODS Healthy-weight children ages 9-12 years (n = 20) reported to the laboratory for 1 baseline and 2 experimental visits (EX and SED) each separated by 1 week in a randomized crossover design. Percent body fat, weight (kg), and height (m) were used to calculate fat-mass index (FM index) and fat-free mass index (FFM index; kg/m2). On the EX day, children exercised at 70% estimated VO2peak for 30 minutes on a cycle ergometer while cardiovascular responses and ratings of perceived exertion (RPE) were measured. Objective EI (kcal) was measured at identical meals (breakfast, lunch, snack, and dinner) on the EX and SED days. RESULTS Total EI was not statistically different between the EX and SED days (t = 1.8, p = 0.09). FFM index was positively associated with EI on the EX day (r = 0.54, p < 0.05). RPE was also positively associated with EI on the EX day (r = 0.82, p < 0.001). Together, FFM index and RPE explained 77% of the variability in EX day EI (F(2,17) = 26.4, p < 0.001). For each unit increase in RPE, children consumed ~270 more calories on the EX day. A similar pattern of associations was observed on the SED day. CONCLUSION FFM index was positively associated with EI on the EX day. Despite experiencing the same 70% relative exercise intensity, increased perceived difficulty predicted greater EI on both the EX and SED day. These findings demonstrate a role for both FFM and RPE in explaining EI variability in children. PMID:27902529
Exercise training normalizes renal blood flow responses to acute hypoxia in experimental heart failure: role of the α1-adrenergic receptor.

PubMed

Pügge, Carolin; Mediratta, Jai; Marcus, Noah J; Schultz, Harold D; Schiller, Alicia M; Zucker, Irving H

2016-02-01

Recent data suggest that exercise training (ExT) is beneficial in chronic heart failure (CHF) because it improves autonomic and peripheral vascular function. In this study, we hypothesized that ExT in the CHF state ameliorates the renal vasoconstrictor responses to hypoxia and that this beneficial effect is mediated by changes in α1-adrenergic receptor activation. CHF was induced in rabbits. Renal blood flow (RBF) and renal vascular conductance (RVC) responses to 6 min of 5% isocapnic hypoxia were assessed in the conscious state in sedentary (SED) and ExT rabbits with CHF with and without α1-adrenergic blockade. α1-adrenergic receptor expression in the kidney cortex was also evaluated. A significant decline in baseline RBF and RVC and an exaggerated renal vasoconstriction during acute hypoxia occurred in CHF-SED rabbits compared with the prepaced state (P < 0.05). ExT diminished the decline in baseline RBF and RVC and restored changes during hypoxia to those of the prepaced state. α1-adrenergic blockade partially prevented the decline in RBF and RVC in CHF-SED rabbits and eliminated the differences in hypoxia responses between SED and ExT animals. Unilateral renal denervation (DnX) blocked the hypoxia-induced renal vasoconstriction in CHF-SED rabbits. α1-adrenergic protein in the renal cortex of animals with CHF was increased in SED animals and normalized after ExT. These data provide evidence that the acute decline in RBF during hypoxia is caused entirely by the renal nerves but is only partially mediated by α1-adrenergic receptors. Nonetheless, α1-adrenergic receptors play an important role in the beneficial effects of ExT in the kidney. Copyright © 2016 the American Physiological Society.
Increase in socioeconomic inequalities in mortality in a Southern European region: a small-area ecological study.

PubMed

Gandarillas, A M; Domínguez-Berjón, M F; Soto, M J

2016-06-01

This study sought to describe the total mortality trend by socioeconomic deprivation (SED) in the Madrid Autonomous Region, by sex and age group. Cross-sectional ecological study by census tract, in two periods: 1994-2000 (P1) with SED of 1996 census and 2001-07 (P2) with SED of 2001 census. We calculated the relative risks (RRs) and their 95% credibility intervals (95% CIs) by SED quintile (Q), taking the quintile of least deprivation as reference. Besag-York-Mollié ecological regression models and the Integrated Nested Laplace Approximation procedure were applied. The absolute differences in age-standardized rates were compared by SED quintile. Inequalities decreased in young adults: among men aged 20-39 years, the RR in Q5 versus Q1 ranged from 2.73 (95% CI, 2.51-3.02) in P1 to 1.93 (95% CI, 1.76-2.15) in P2, due to the greater improvement in the most underprivileged groups. In contrast, there was an increase in SED-related mortality in the 40-79 age group. Among men aged 40-59 years, the RR in Q5 versus Q1 rose from 1.88 (95% CI, 1.76-2.02) in P1 to 2.29 (95% CI, 2.17-2.43) in P2; the improvement was greater in the most privileged groups. In a context of an economic boom, inequalities were observed to increase among adults by a greater improvement in the most privileged groups. © The Author 2015. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Increased Brain Glucose Uptake After 12 Weeks of Aerobic High-Intensity Interval Training in Young and Older Adults.

PubMed

Robinson, Matthew M; Lowe, Val J; Nair, K Sreekumaran

2018-01-01

Aerobic exercise training can increase brain volume and blood flow, but the impact on brain metabolism is less known. We determined whether high-intensity interval training (HIIT) increases brain metabolism by measuring brain glucose uptake in younger and older adults. Brain glucose uptake was measured before and after HIIT or a sedentary (SED) control period within a larger exercise study. Study procedures were performed at the Mayo Clinic in Rochester, MN. Participants were younger (18 to 30 years) or older (65 to 80 years) SED adults who were free of major medical conditions. Group sizes were 15 for HIIT (nine younger and six older) and 12 for SED (six younger and six older). Participants completed 12 weeks of HIIT or SED. HIIT was 3 days per week of 4 × 4 minute intervals at over 90% of peak aerobic capacity (VO2peak) with 2 days per week of treadmill walking at 70% VO2peak. Resting brain glucose uptake was measured using 18F-fluorodeoxyglucose positron emission tomography scans at baseline and at week 12. Scans were performed at 96 hours after exercise. VO2peak was measured by indirect calorimetry. Glucose uptake increased significantly in the parietal-temporal and caudate regions after HIIT compared with SED. The gains with HIIT were not observed in all brain regions. VO2peak was increased for all participants after HIIT and did not change with SED. We demonstrate that brain glucose metabolism increased after 12 weeks of HIIT in adults in regions where it is reduced in Alzheimer's disease. Copyright © 2017 Endocrine Society
Galaxy and mass assembly (GAMA): the consistency of GAMA and WISE derived mass-to-light ratios

NASA Astrophysics Data System (ADS)

Kettlety, T.; Hesling, J.; Phillipps, S.; Bremer, M. N.; Cluver, M. E.; Taylor, E. N.; Bland-Hawthorn, J.; Brough, S.; De Propris, R.; Driver, S. P.; Holwerda, B. W.; Kelvin, L. S.; Sutherland, W.; Wright, A. H.

2018-01-01

Recent work has suggested that mid-IR wavelengths are optimal for estimating the mass-to-light ratios of stellar populations and hence the stellar masses of galaxies. We compare stellar masses deduced from spectral energy distribution (SED) models, fitted to multiwavelength optical-NIR photometry, to luminosities derived from WISE photometry in the W1 and W2 bands at 3.6 and 4.5 μm for non-star forming galaxies. The SED-derived masses for a carefully selected sample of low-redshift (z ≤ 0.15) passive galaxies agree with the prediction from stellar population synthesis models such that M*/LW1 ≃ 0.6 for all such galaxies, independent of other stellar population parameters. The small scatter between masses predicted from the optical SED and from the WISE measurements implies that random errors (as opposed to systematic ones such as the use of different initial mass functions) are smaller than previous, deliberately conservative, estimates for the SED fits. This test is subtly different from simultaneously fitting at a wide range of optical and mid-IR wavelengths, which may just generate a compromised fit: we are directly checking that the best-fitting model to the optical data generates an SED whose M*/LW1 is also consistent with separate mid-IR data. We confirm that for passive low-redshift galaxies a fixed M*/LW1 = 0.65 can generate masses at least as accurate as those obtained from more complex methods. Going beyond the mean value, in agreement with expectations from the models, we see a modest change in M*/LW1 with SED fitted stellar population age but an insignificant one with metallicity.
The effects of the WISE/ GALEX photometry for the SED-fitting with M31 star clusters and candidates

NASA Astrophysics Data System (ADS)

Fan, Zhou; Wang, Song

2017-10-01

Spectral energy distribution (SED) fitting of stellar population synthesis models is an important and popular way to constrain the physical parameters—e.g., the ages, metallicities, masses for stellar population analysis. The previous works suggest that both blue-bands and red-bands photometry works for the SED-fitting. Either blue-domained or red-domained SED-fitting usually lead to the unreliable or biased results. Meanwhile, it seems that extending the wavelength coverage could be helpful. Since the Galaxy Evolution Explorer ( GALEX) and Wide-field Infrared Survey Explorer (WISE) provide the FUV/NUV and mid-infrared W1/W2 band data, we extend the SED-fitting to a wider wavelength coverage. In our work, we analyzed the effect of adding the FUV/NUV and W1/W2 band to the optical and near-infrared UBVRIJHK bands for the fitting with the (Bruzual and Charlot in Mon. Not. R. Astron. Soc. 344, 1000, 2003) (BC03) models and galev models. It is found that the FUV/NUV bands data affect the fitting results of both ages and metallicities much more significantly than that of the WISE W1/W2 band with the BC03 models. While for the galev models, the effect of the WISE W1/W2 band for the metallicity fitting seems comparable to that of GALEX FUV/NUV bands, but for age the effect of the W1/W2 band seems less crucial than that of the FUV/NUV bands. Thus we conclude that the GALEX FUV/NUV bands are more crucial for the SED-fitting of ages and metallicities, than the other bands, and the high-quality UV data (with high photometry precision) are required.
THE YOUNG STELLAR POPULATION OF LYNDS 1340. AN INFRARED VIEW

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kun, M.; Moór, A.; Wolf-Chase, G.

We present results of an infrared study of the molecular cloud Lynds 1340, forming three groups of low- and intermediate-mass stars. Our goals are to identify and characterize the young stellar population of the cloud, study the relationships between the properties of the cloud and the emergent stellar groups, and integrate L1340 into the picture of the star-forming activity of our Galactic environment. We selected candidate young stellar objects (YSOs) from the Spitzer and WISE databases using various published color criteria and classified them based on the slope of the spectral energy distribution (SED). We identified 170 Class II, 27more » flat SED, and 45 Class 0/I sources. High angular resolution near-infrared observations of the RNO 7 cluster, embedded in L1340, revealed eight new young stars of near-infrared excess. The surface density distribution of YSOs shows three groups, associated with the three major molecular clumps of L1340, each consisting of ≲100 members, including both pre-main-sequence stars and embedded protostars. New Herbig–Haro objects were identified in the Spitzer images. Our results demonstrate that L1340 is a prolific star-forming region of our Galactic environment in which several specific properties of the intermediate-mass mode of star formation can be studied in detail.« less
JPRS Report East Europe.

DTIC Science & Technology

1990-06-01

the brief signed, among others, by Jakob Moneta, of Stalinism and the refusal of the SED leadership to face Hermann Weber, Peter von Oertzen, Lev...Merker, Kurt Mueller, Fritz Sperling , the investigation of the purges in the SED, about which Paul Szillat, and Stanislaus Trabalski). In 1946, 14
Analytical investigation of the dynamics of tethered constellations in Earth orbit, phase 2

NASA Technical Reports Server (NTRS)

Lorenzini, Enrico C.; Gullahorn, Gordon E.; Cosmo, Mario L.; Estes, Robert D.; Grossi, Mario D.

1994-01-01

This final report covers nine years of research on future tether applications and on the actual flights of the Small Expendable Deployment System (SEDS). Topics covered include: (1) a description of numerical codes used to simulate the orbital and attitude dynamics of tethered systems during station keeping and deployment maneuvers; (2) a comparison of various tethered system simulators; (3) dynamics analysis, conceptual design, potential applications and propagation of disturbances and isolation from noise of a variable gravity/microgravity laboratory tethered to the Space Station; (4) stability of a tethered space centrifuge; (5) various proposed two-dimensional tethered structures for low Earth orbit for use as planar array antennas; (6) tethered high gain antennas; (7) numerical calculation of the electromagnetic wave field on the Earth's surface on an electrodynamically tethered satellite; (8) reentry of tethered capsules; (9) deployment dynamics of SEDS-1; (10) analysis of SEDS-1 flight data; and (11) dynamics and control of SEDS-2.
Lyα emitters in the GOODS-S field. A powerful pure nebular SED with N IV] emission at z = 5.563

NASA Astrophysics Data System (ADS)

Raiter, A.; Fosbury, R. A. E.; Teimoorinia, H.

2010-02-01

Context. The Great Observatories Origins Deep Survey (GOODS) has provided us with one of the deepest multi-wavelength views of the distant universe. The combination of multi-band photometry and optical spectroscopy has resulted in the identification of sources whose redshifts extend to values in excess of six. Amongst these distant sources are Lyα emitters whose nature must be deduced by clearly identifying the different components that contribute to the measured SED. Aims: From a sample of Lyα emitters in the GOODS-S field with uncontaminated photometry and optical (red) spectroscopy, we select a spatially compact object at a redshift of 5.563 (Lyα) that shows a second emission line, identified as N IV] 1486 Å. The SED is modelled in a way that accounts for both the N IV] line emission and the photometry in a self-consistent way. Methods: The photoionization code CLOUDY is used to calculate a range of nebular models as a function of stellar ionizing source temperature, ionization parameter, density and nebular metallicity. We compare the theoretical and observed magnitudes and search for the model parameters that also reproduce the observed N IV] luminosity and equivalent width. Results: A nebular model with a hot blackbody ionizing source of around 100 kK and a nebular metallicity of ~5% of solar is able to fit the observed SED and, in particular, explain the large apparent Balmer break which is inferred from the pure stellar population model fitting conventionally applied to multi-band photometric observations. In our model, an apparent spectral break is produced by strong [O III] 4959, 5007 Å emission falling in one of the IR bands (IRAC1 in this case). A lower limit on the total baryonic mass of a model of this type is 3.2 ×10^8~M⊙. Conclusions: It is argued that objects with Lyα emission at high redshift that show an apparent Balmer break may have their SED dominated by nebular emission and so could possibly be identified with very young starbursting galaxies rather than massive evolved stellar populations. Detailed studies of these emission nebulæ with large telescopes will provide a unique insight into very early chemical evolution. Based on observations made at the European Southern Observatory, Paranal, Chile (ESO programme 170.A-0788) The Great Observatories Origins Deep Survey: ESO Public Observations of the SIRTF Legacy/HST Treasury/Chandra Deep Field South.); on observations obtained with the NASA/ESA Hubble Space Telescope obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy (AURA), Inc.; and on observations made with the Spitzer Space Telescope, which is operated by the Jet Propulsion Laboratory, California Institute of Technology under a contract with NASA.
Microbial fuel cells for inexpensive continuous in-situ monitoring of groundwater quality.

PubMed

Velasquez-Orta, S B; Werner, D; Varia, J C; Mgana, S

2017-06-15

Online monitoring of groundwater quality in shallow wells to detect faecal or organic pollution could dramatically improve understanding of health risks in unplanned peri-urban settlements. Microbial fuel cells (MFC) are devices able to generate electricity from the organic matter content in faecal pollution making them suitable as biosensors. In this work, we evaluate the suitability of four microbial fuel cell systems placed in different regions of a groundwater well for the low-cost monitoring of a faecal pollution event. Concepts created include the use of a sediment/bulk liquid MFC (SED/BL), a sediment/sediment MFC (SED/SED), a bulk liquid/air MFC (BL/Air), and a bulk liquid/bulk liquid MFC (BL/BL). MFC electrodes assembly aimed to use inexpensive, durable, materials, which would produce a signal after a contamination event without external energy or chemical inputs. All MFC configurations were responsive to a contamination event, however SED/SED and BL/Air MFC concepts failed to deliver a reproducible output within the tested period of time. BL/BL MFC and SED/BL MFCs presented an increase in the average current after contamination from -0.75 ± 0.35 μA to -0.66 ± 0.41 μA, and 0.07 ± 0.2 mA to 0.11 ± 0.03 mA, respectively. Currents produced by the SED/BL MFC (SMFC) were considerably higher than for the BL/BL MFCs, making them more responsive, readable and graphically visible. A factorial design of experiments (DOE) was applied to evaluate which environmental and design factors had the greatest effect on current response in a contamination event. Within the ranges of variables tested, salinity, temperature and external resistance, only temperature presented a statistically significant effect (p = 0.045). This showed that the biosensor response would be sensitive to fluctuations in temperature but not to changes in salinity, or external resistances produced from placing electrodes at different distances within a groundwater well. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.
System development of the Screwworm Eradication Data System (SEDS) algorithm

NASA Technical Reports Server (NTRS)

Arp, G.; Forsberg, F.; Giddings, L.; Phinney, D.

1976-01-01

The use of remotely sensed data is reported in the eradication of the screwworm and in the study of the role of the weather in the activity and development of the screwworm fly. As a result, the Screwworm Eradication Data System (SEDS) algorithm was developed.

APEX/SABOCA observations of small-scale structure of infrared-dark clouds . I. Early evolutionary stages of star-forming cores

NASA Astrophysics Data System (ADS)

Ragan, Sarah E.; Henning, Thomas; Beuther, Henrik

2013-11-01

Infrared-dark clouds (IRDCs) harbor the early phases of cluster and high-mass star formation and are comprised of cold (~20 K), dense (n > 104 cm-3) gas. The spectral energy distribution (SED) of IRDCs is dominated by the far-infrared and millimeter wavelength regime, and our initial Herschel study examined IRDCs at the peak of the SED with high angular resolution. Here we present a follow-up study using the SABOCA instrument on APEX which delivers 7.8″ angular resolution at 350 μm, matching the resolution we achieved with Herschel/PACS, and allowing us to characterize substructure on ~0.1 pc scales. Our sample of 11 nearby IRDCs are a mix of filamentary and clumpy morphologies, and the filamentary clouds show significant hierarchical structure, while the clumpy IRDCs exhibit little hierarchical structure. All IRDCs, regardless of morphology, have about 14% of their total mass in small scale core-like structures which roughly follow a trend of constant volume density over all size scales. Out of the 89 protostellar cores we identified in this sample with Herschel, we recover 40 of the brightest and re-fit their SEDs and find their properties agree fairly well with our previous estimates (⟨ T ⟩ ~ 19 K). We detect a new population of "cold cores" which have no 70 μm counterpart, but are 100 and 160 μm-bright, with colder temperatures (⟨ T ⟩ ~ 16 K). This latter population, along with SABOCA-only detections, are predominantly low-mass objects, but their evolutionary diagnostics are consistent with the earliest starless or prestellar phase of cores in IRDCs. Based on observations carried out with the Atacama Pathfinder Experiment (APEX). APEX is a collaboration between Max Planck Institut für Radioastronomie (MPIfR), Onsala Space Observatory (OSO), and the European Southern Observatory (ESO).Appendices are available in electronic form at http://www.aanda.org
The awakening of the γ-ray narrow-line Seyfert 1 galaxy PKS 1502+036

NASA Astrophysics Data System (ADS)

D'Ammando, F.; Orienti, M.; Finke, J.; Hovatta, T.; Giroletti, M.; Max-Moerbeck, W.; Pearson, T. J.; Readhead, A. C. S.; Reeves, R. A.; Richards, J. L.

2016-12-01

After a long low-activity period, a γ-ray flare from the narrow-line Seyfert 1 PKS 1502+036 (z = 0.4089) was detected by the Large Area Telescope (LAT) on board Fermi in 2015. On 2015 December 20, the source reached a daily peak flux, in the 0.1-300 GeV band, of (93 ± 19) × 10-8 ph cm-2 s-1, attaining a flux of (237 ± 71) × 10-8 ph cm-2 s-1 on 3-h time-scales, which corresponds to an isotropic luminosity of (7.3 ± 2.1) × 1047 erg s-1. The γ-ray flare was not accompanied by significant spectral changes. We report on multiwavelength radio-to-γ-ray observations of PKS 1502+036 during 2008 August-2016 March by Fermi-LAT, Swift, XMM-Newton, Catalina Real-Time Transient Survey and the Owens Valley Radio Observatory (OVRO). An increase in activity was observed on 2015 December 22 by Swift in optical, UV and X-rays. The OVRO 15 GHz light curve reached the highest flux density observed from this source on 2016 January 12, indicating a delay of about three weeks between the γ-ray and 15 GHz emission peaks. This suggests that the γ-ray-emitting region is located beyond the broad-line region. We compared the spectral energy distribution (SED) of an average activity state with that of the flaring state. The two SED, with the high-energy bump modelled as an external Compton component with seed photons from a dust torus, could be fitted by changing the electron distribution parameters as well as the magnetic field. The fit of the disc emission during the average state constrains the black hole mass to values lower than 108 M⊙. The SED, high-energy emission mechanisms and γ-ray properties of the source resemble those of a flat spectrum radio quasar.
Characterizing Quasar Outflows III: SEDs, and Bolometric Luminosity Estimates

NASA Astrophysics Data System (ADS)

Richmond, Joseph; Robbins, J. M.; Ganguly, R.; Stark, M. A.; Christenson, D. H.; Derseweh, J. A.; Townsend, S. L.

2012-05-01

Galaxy evolution models have shown that quasars are a crucial ingredient in the evolution of massive galaxies. Outflows play a key role in the story of quasars and their host galaxies, by helping regulate the accretion process, the star-formation rate and mass of the host galaxy (i.e., feedback). The prescription for modeling outflows as a contributor to feedback requires knowledge of the outflow velocity, geometry, and column density. In particular, we need to understand how these depend on physical parameters and how much is determined stochastically (and with what distribution). For this purpose, we are examining a sample of 11000 z=1.7-2.0 quasars from the Sloan Digital Sky Survey. This redshift range permits the following from the SDSS spectra: (1) separation of objects that do and do not exhibit outflows; (2) classification/measurement of outflow properties (ionization, velocity, velocity width); and (3) measurements of UV emission line and continuum parameters. In this poster, we add photometry from both the Two Micron All-Sky Survey (2MASS) and from the Wide-Field Infrared Survey Explorer (WISE). 2MASS photometry covers the rest-frame optical regime of these qusars, while the WISE W1, W2, and W3 bands cover the rest-frame wavelength ranges 0.9-1.27 micron, 1.35-1.75 micron, and 2.52-5.51 micron, respectively. The preliminary release of WISE data cover 3800 of our quasars. In an accompnying poster, we have subjectively divided these quasars into four categories: broad absorption-line quasars (2700 objects), associated absorption-line quasars (1700 objects), reddened quasars (160 objects), and unabsorbed/unreddened quasars (6300 objects). Here, we present average SEDs for these subsamples, estimates of bolometric luminosity, and explore changes in SED based on both outflow properties and quasar physical properties. This material is based upon work supported by the National Aeronautics and Space Administration under Grant No. 09-ADP09-0016 issued through the Astrophysics Data Analysis Program.
DOE Office of Scientific and Technical Information (OSTI.GOV)

D'Ammando, F.; Orienti, M.; Finke, J.

After a long low-activity period, we detected a γ-ray flare from the narrow-line Seyfert 1 PKS 1502+036 (z = 0.4089) by the Large Area Telescope (LAT) on board Fermi in 2015. On 2015 December 20, the source reached a daily peak flux, in the 0.1–300 GeV band, of (93 ± 19) × 10 -8 ph cm -2 s -1, attaining a flux of (237 ± 71) × 10 -8 ph cm -2 s -1 on 3-h time-scales, which corresponds to an isotropic luminosity of (7.3 ± 2.1) × 10 47 erg s -1. The γ-ray flare was not accompanied bymore » significant spectral changes. We report on multiwavelength radio-to-γ-ray observations of PKS 1502+036 during 2008 August–2016 March by Fermi-LAT, Swift, XMM–Newton, Catalina Real-Time Transient Survey and the Owens Valley Radio Observatory (OVRO). An increase in activity was observed on 2015 December 22 by Swift in optical, UV and X-rays. The OVRO 15 GHz light curve reached the highest flux density observed from this source on 2016 January 12, indicating a delay of about three weeks between the γ-ray and 15 GHz emission peaks. Furthermore, this suggests that the γ-ray-emitting region is located beyond the broad-line region. We also compared the spectral energy distribution (SED) of an average activity state with that of the flaring state. The two SED, with the high-energy bump modelled as an external Compton component with seed photons from a dust torus, could be fitted by changing the electron distribution parameters as well as the magnetic field. Furthermore, the fit of the disc emission during the average state constrains the black hole mass to values lower than 108 M⊙. The SED, high-energy emission mechanisms and γ-ray properties of the source resemble those of a flat spectrum radio quasar.« less
The awakening of the γ-ray narrow-line Seyfert 1 galaxy PKS 1502+036

DOE PAGES

D'Ammando, F.; Orienti, M.; Finke, J.; ...

2016-09-14

After a long low-activity period, we detected a γ-ray flare from the narrow-line Seyfert 1 PKS 1502+036 (z = 0.4089) by the Large Area Telescope (LAT) on board Fermi in 2015. On 2015 December 20, the source reached a daily peak flux, in the 0.1–300 GeV band, of (93 ± 19) × 10 -8 ph cm -2 s -1, attaining a flux of (237 ± 71) × 10 -8 ph cm -2 s -1 on 3-h time-scales, which corresponds to an isotropic luminosity of (7.3 ± 2.1) × 10 47 erg s -1. The γ-ray flare was not accompanied bymore » significant spectral changes. We report on multiwavelength radio-to-γ-ray observations of PKS 1502+036 during 2008 August–2016 March by Fermi-LAT, Swift, XMM–Newton, Catalina Real-Time Transient Survey and the Owens Valley Radio Observatory (OVRO). An increase in activity was observed on 2015 December 22 by Swift in optical, UV and X-rays. The OVRO 15 GHz light curve reached the highest flux density observed from this source on 2016 January 12, indicating a delay of about three weeks between the γ-ray and 15 GHz emission peaks. Furthermore, this suggests that the γ-ray-emitting region is located beyond the broad-line region. We also compared the spectral energy distribution (SED) of an average activity state with that of the flaring state. The two SED, with the high-energy bump modelled as an external Compton component with seed photons from a dust torus, could be fitted by changing the electron distribution parameters as well as the magnetic field. Furthermore, the fit of the disc emission during the average state constrains the black hole mass to values lower than 108 M⊙. The SED, high-energy emission mechanisms and γ-ray properties of the source resemble those of a flat spectrum radio quasar.« less
Use of classification trees to apportion single echo detections to species: Application to the pelagic fish community of Lake Superior

USGS Publications Warehouse

Yule, Daniel L.; Adams, Jean V.; Hrabik, Thomas R.; Vinson, Mark R.; Woiak, Zebadiah; Ahrenstroff, Tyler D.

2013-01-01

Acoustic methods are used to estimate the density of pelagic fish in large lakes with results of midwater trawling used to assign species composition. Apportionment in lakes having mixed species can be challenging because only a small fraction of the water sampled acoustically is sampled with trawl gear. Here we describe a new method where single echo detections (SEDs) are assigned to species based on classification tree models developed from catch data that separate species based on fish size and the spatial habitats they occupy. During the summer of 2011, we conducted a spatially-balanced lake-wide acoustic and midwater trawl survey of Lake Superior. A total of 51 sites in four bathymetric depth strata (0–30 m, 30–100 m, 100–200 m, and >200 m) were sampled. We developed classification tree models for each stratum and found fish length was the most important variable for separating species. To apply these trees to the acoustic data, we needed to identify a target strength to length (TS-to-L) relationship appropriate for all abundant Lake Superior pelagic species. We tested performance of 7 general (i.e., multi-species) relationships derived from three published studies. The best-performing relationship was identified by comparing predicted and observed catch compositions using a second independent Lake Superior data set. Once identified, the relationship was used to predict lengths of SEDs from the lake-wide survey, and the classification tree models were used to assign each SED to a species. Exotic rainbow smelt (Osmerus mordax) were the most common species at bathymetric depths 100 m (384 million; 6.0 kt). Cisco (Coregonus artedi) were widely distributed over all strata with their population estimated at 182 million (44 kt). The apportionment method we describe should be transferable to other large lakes provided fish are not tightly aggregated, and an appropriate TS-to-L relationship for abundant pelagic fish species can be determined.
Effects of exercise intensity on spatial memory performance and hippocampal synaptic plasticity in transient brain ischemic rats.

PubMed

Shih, Pei-Cheng; Yang, Yea-Ru; Wang, Ray-Yau

2013-01-01

Memory impairment is commonly noted in stroke survivors, and can lead to delay of functional recovery. Exercise has been proved to improve memory in adult healthy subjects. Such beneficial effects are often suggested to relate to hippocampal synaptic plasticity, which is important for memory processing. Previous evidence showed that in normal rats, low intensity exercise can improve synaptic plasticity better than high intensity exercise. However, the effects of exercise intensities on hippocampal synaptic plasticity and spatial memory after brain ischemia remain unclear. In this study, we investigated such effects in brain ischemic rats. The middle cerebral artery occlusion (MCAO) procedure was used to induce brain ischemia. After the MCAO procedure, rats were randomly assigned to sedentary (Sed), low-intensity exercise (Low-Ex), or high-intensity exercise (High-Ex) group. Treadmill training began from the second day post MCAO procedure, 30 min/day for 14 consecutive days for the exercise groups. The Low-Ex group was trained at the speed of 8 m/min, while the High-Ex group at the speed of 20 m/min. The spatial memory, hippocampal brain-derived neurotrophic factor (BDNF), synapsin-I, postsynaptic density protein 95 (PSD-95), and dendritic structures were examined to document the effects. Serum corticosterone level was also quantified as stress marker. Our results showed the Low-Ex group, but not the High-Ex group, demonstrated better spatial memory performance than the Sed group. Dendritic complexity and the levels of BDNF and PSD-95 increased significantly only in the Low-Ex group as compared with the Sed group in bilateral hippocampus. Notably, increased level of corticosterone was found in the High-Ex group, implicating higher stress response. In conclusion, after brain ischemia, low intensity exercise may result in better synaptic plasticity and spatial memory performance than high intensity exercise; therefore, the intensity is suggested to be considered during exercise training.
A high and low noise model for strong motion accelerometers

NASA Astrophysics Data System (ADS)

Clinton, J. F.; Cauzzi, C.; Olivieri, M.

2010-12-01

We present reference noise models for high-quality strong motion accelerometer installations. We use continuous accelerometer data acquired by the Swiss Seismological Service (SED) since 2006 and other international high-quality accelerometer network data to derive very broadband (50Hz-100s) high and low noise models. The proposed noise models are compared to the Peterson (1993) low and high noise models designed for broadband seismometers; the datalogger self-noise; background noise levels at existing Swiss strong motion stations; and typical earthquake signals recorded in Switzerland and worldwide. The standard strong motion station operated by the SED consists of a Kinemetrics Episensor (2g clip level; flat acceleration response from 200 Hz to DC; <155dB dynamic range) coupled with a 24-bit Nanometrics Taurus datalogger. The proposed noise models are based on power spectral density (PSD) noise levels for each strong motion station computed via PQLX (McNamara and Buland, 2004) from several years of continuous recording. The 'Accelerometer Low Noise Model', ALNM, is dominated by instrument noise from the sensor and datalogger. The 'Accelerometer High Noise Model', AHNM, reflects 1) at high frequencies the acceptable site noise in urban areas, 2) at mid-periods the peak microseismal energy, as determined by the Peterson High Noise Model and 3) at long periods the maximum noise observed from well insulated sensor / datalogger systems placed in vault quality sites. At all frequencies, there is at least one order of magnitude between the ALNM and the AHNM; at high frequencies (> 1Hz) this extends to 2 orders of magnitude. This study provides remarkable confirmation of the capability of modern strong motion accelerometers to record low-amplitude ground motions with seismic observation quality. In particular, an accelerometric station operating at the ALNM is capable of recording the full spectrum of near source earthquakes, out to 100 km, down to M2. Of particular interest for the SED, this study provides acceptable noise limits for candidate sites for the on-going Strong Motion Network modernisation.
Socioeconomic Determinants of Antibiotic Consumption in the State of São Paulo, Brazil: The Effect of Restricting Over-The-Counter Sales.

PubMed

Kliemann, Breno S; Levin, Anna S; Moura, M Luísa; Boszczowski, Icaro; Lewis, James J

2016-01-01

Improper antibiotic use is one of the main drivers of bacterial resistance to antibiotics, increasing infectious diseases morbidity and mortality and raising costs of healthcare. The level of antibiotic consumption has been shown to vary according to socioeconomic determinants (SED) such as income and access to education. In many Latin American countries, antibiotics could be easily purchased without a medical prescription in private pharmacies before enforcement of restrictions on over-the-counter (OTC) sales in recent years. Brazil issued a law abolishing OTC sales in October 2010. This study seeks to find SED of antibiotic consumption in the Brazilian state of São Paulo (SSP) and to estimate the impact of the 2010 law. Data on all oral antibiotic sales having occurred in the private sector in SSP from 2008 to 2012 were pooled into the 645 municipalities of SSP. Linear regression was performed to estimate consumption levels that would have occurred in 2011 and 2012 if no law regulating OTC sales had been issued in 2010. These values were compared to actual observed levels, estimating the effect of this law. Linear regression was performed to find association of antibiotic consumption levels and of a greater effect of the law with municipality level data on SED obtained from a nationwide census. Oral antibiotic consumption in SSP rose from 8.44 defined daily doses per 1,000 inhabitants per day (DID) in 2008 to 9.95 in 2010, and fell to 8.06 DID in 2012. Determinants of a higher consumption were higher human development index, percentage of urban population, density of private health establishments, life expectancy and percentage of females; lower illiteracy levels and lower percentage of population between 5 and 15 years old. A higher percentage of females was associated with a stronger effect of the law. SSP had similar antibiotic consumption levels as the whole country of Brazil, and they were effectively reduced by the policy.
RiseTx: testing the feasibility of a web application for reducing sedentary behavior among prostate cancer survivors receiving androgen deprivation therapy.

PubMed

Trinh, Linda; Arbour-Nicitopoulos, Kelly P; Sabiston, Catherine M; Berry, Scott R; Loblaw, Andrew; Alibhai, Shabbir M H; Jones, Jennifer M; Faulkner, Guy E

2018-06-07

Given the high levels of sedentary time and treatment-related side effects in prostate cancer survivors (PCS), interventions targeting sedentary behavior (SED) may be more sustainable compared to physical activity (PA). To examine the feasibility of a web-based intervention (RiseTx) for reducing SED and increasing moderate-to-vigorous physical activity (MVPA) among PCS undergoing ADT. Secondary outcomes include changes in SED, MVPA, light intensity PA, and quality of life. Forty-six PCS were recruited from two cancer centres in Toronto, Ontario, Canada between July 2015-October 2016. PCS were given an activity tracker (Jawbone), access to the RiseTx website program, and provided with a goal of increasing walking by 3000 daily steps above baseline levels over a 12-week period. A range of support tools were progressively released to reduce SED time (e.g., self-monitoring of steps) during the five-phase program. Objective measures of SED, MVPA, and daily steps were compared across the 12-week intervention using linear mixed models. Of the 46 PCS enrolled in the study, 42 completed the SED intervention, representing a 9% attrition rate. Measurement completion rates were 97 and 65% at immediately post-intervention and 12-week follow-up for all measures, respectively. Overall adherence was 64% for total number of logins (i.e., > 3 visits each week). Sample mean age was 73.2 ± 7.3 years, mean BMI was 28.0 ± 3.0 kg/m 2 , mean number of months since diagnosis was 93.6 ± 71.2, and 72% had ADT administered continuously. Significant reductions of 455.4 weekly minutes of SED time were observed at post-intervention (p = .005). Significant increases of + 44.1 for weekly minutes of MVPA was observed at immediately post-intervention (p = .010). There were significant increases in step counts of + 1535 steps from baseline to post-intervention (p < .001). RiseTx was successful in reducing SED and increasing MVPA in PCS. PCS were satisfied with the intervention and its components. Additional strategies may be needed though for maintenance of behavior change. The next step for RiseTx is to replicate these findings in a larger, randomized controlled trial that will have the potential for reducing sedentary time among PCS. NCT03321149 (ClinicalTrials.gov Identifier).
DECONVOLUTION OF IMAGES FROM BLAST 2005: INSIGHT INTO THE K3-50 AND IC 5146 STAR-FORMING REGIONS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roy, Arabindo; Netterfield, Calvin B.; Ade, Peter A. R.

2011-04-01

We present an implementation of the iterative flux-conserving Lucy-Richardson (L-R) deconvolution method of image restoration for maps produced by the Balloon-borne Large Aperture Submillimeter Telescope (BLAST). Compared to the direct Fourier transform method of deconvolution, the L-R operation restores images with better-controlled background noise and increases source detectability. Intermediate iterated images are useful for studying extended diffuse structures, while the later iterations truly enhance point sources to near the designed diffraction limit of the telescope. The L-R method of deconvolution is efficient in resolving compact sources in crowded regions while simultaneously conserving their respective flux densities. We have analyzed itsmore » performance and convergence extensively through simulations and cross-correlations of the deconvolved images with available high-resolution maps. We present new science results from two BLAST surveys, in the Galactic regions K3-50 and IC 5146, further demonstrating the benefits of performing this deconvolution. We have resolved three clumps within a radius of 4.'5 inside the star-forming molecular cloud containing K3-50. Combining the well-resolved dust emission map with available multi-wavelength data, we have constrained the spectral energy distributions (SEDs) of five clumps to obtain masses (M), bolometric luminosities (L), and dust temperatures (T). The L-M diagram has been used as a diagnostic tool to estimate the evolutionary stages of the clumps. There are close relationships between dust continuum emission and both 21 cm radio continuum and {sup 12}CO molecular line emission. The restored extended large-scale structures in the Northern Streamer of IC 5146 have a strong spatial correlation with both SCUBA and high-resolution extinction images. A dust temperature of 12 K has been obtained for the central filament. We report physical properties of ten compact sources, including six associated protostars, by fitting SEDs to multi-wavelength data. All of these compact sources are still quite cold (typical temperature below {approx} 16 K) and are above the critical Bonner-Ebert mass. They have associated low-power young stellar objects. Further evidence for starless clumps has also been found in the IC 5146 region.« less
Deconvolution of Images from BLAST 2005: Insight into the K3-50 and IC 5146 Star-forming Regions

NASA Astrophysics Data System (ADS)

Roy, Arabindo; Ade, Peter A. R.; Bock, James J.; Brunt, Christopher M.; Chapin, Edward L.; Devlin, Mark J.; Dicker, Simon R.; France, Kevin; Gibb, Andrew G.; Griffin, Matthew; Gundersen, Joshua O.; Halpern, Mark; Hargrave, Peter C.; Hughes, David H.; Klein, Jeff; Marsden, Gaelen; Martin, Peter G.; Mauskopf, Philip; Netterfield, Calvin B.; Olmi, Luca; Patanchon, Guillaume; Rex, Marie; Scott, Douglas; Semisch, Christopher; Truch, Matthew D. P.; Tucker, Carole; Tucker, Gregory S.; Viero, Marco P.; Wiebe, Donald V.

2011-04-01

We present an implementation of the iterative flux-conserving Lucy-Richardson (L-R) deconvolution method of image restoration for maps produced by the Balloon-borne Large Aperture Submillimeter Telescope (BLAST). Compared to the direct Fourier transform method of deconvolution, the L-R operation restores images with better-controlled background noise and increases source detectability. Intermediate iterated images are useful for studying extended diffuse structures, while the later iterations truly enhance point sources to near the designed diffraction limit of the telescope. The L-R method of deconvolution is efficient in resolving compact sources in crowded regions while simultaneously conserving their respective flux densities. We have analyzed its performance and convergence extensively through simulations and cross-correlations of the deconvolved images with available high-resolution maps. We present new science results from two BLAST surveys, in the Galactic regions K3-50 and IC 5146, further demonstrating the benefits of performing this deconvolution. We have resolved three clumps within a radius of 4farcm5 inside the star-forming molecular cloud containing K3-50. Combining the well-resolved dust emission map with available multi-wavelength data, we have constrained the spectral energy distributions (SEDs) of five clumps to obtain masses (M), bolometric luminosities (L), and dust temperatures (T). The L-M diagram has been used as a diagnostic tool to estimate the evolutionary stages of the clumps. There are close relationships between dust continuum emission and both 21 cm radio continuum and 12CO molecular line emission. The restored extended large-scale structures in the Northern Streamer of IC 5146 have a strong spatial correlation with both SCUBA and high-resolution extinction images. A dust temperature of 12 K has been obtained for the central filament. We report physical properties of ten compact sources, including six associated protostars, by fitting SEDs to multi-wavelength data. All of these compact sources are still quite cold (typical temperature below ~ 16 K) and are above the critical Bonner-Ebert mass. They have associated low-power young stellar objects. Further evidence for starless clumps has also been found in the IC 5146 region.
Strategic Employee Development in The Government Sector

NASA Technical Reports Server (NTRS)

Nguyen, Johnny; Guevara, Nathalie; Barnett, Rebecca; Thorpe, Barbara

2017-01-01

As with many other U.S. agencies, succession planning is becoming a critical need for NASA. The primary drivers include (a) NASA's higher-than-average aged workforce with approximately 50% of employees eligible for retirement within 5 years; and (b) employees who need better developmental conversations to increase morale and retention. This problem is particularly concerning for Safety & Mission Assurance (S&MA) organizations since they traditionally rely on more experienced engineers and specialists to perform their organizations' functions. In response to this challenge, the Kennedy Space Center (KSC) S&MA organization created the Strategic Employee Development (SED) program. The SED program's goal is to provide a proactive method to counter the primary drivers by creating a deeper "bench strength" and providing a more comprehensive developmental feedback experience for the employee. The SED is a new succession planning framework that enables customization to any organization, and in this case, specifically for an S&MA organization. This is accomplished via the identification of key positions, the corresponding critical competencies, and a process to help managers have relevant and meaningful development conversations with the workforce. As a result of the SED, several tools and products were created that allows management to make better strategic workforce decisions. Although there are opportunities for improvement for the SED program, the most important impact has been on the quality of developmental discussions for employees.
Chitosan use in chemical conditioning for dewatering municipal-activated sludge.

PubMed

Zemmouri, H; Mameri, N; Lounici, H

2015-01-01

This work aims to evaluate the potential use of chitosan as an eco-friendly flocculant in chemical conditioning of municipal-activated sludge. Chitosan effectiveness was compared with synthetic cationic polyelectrolyte Sedipur CF802 (Sed CF802) and ferric chloride (FeCl₃). In this context, raw sludge samples from Beni-Messous wastewater treatment plant (WWTP) were tested. The classic jar test method was used to condition sludge samples. Capillary suction time (CST), specific resistance to filtration (SRF), cakes dry solid content and filtrate turbidity were analyzed to determine filterability, dewatering capacity of conditioned sludge and the optimum dose of each conditioner. Data exhibit that chitosan, FeCl₃and Sed CF802 improve sludge dewatering. Optimum dosages of chitosan, Sed CF802 and FeCl₃allowing CST values of 6, 5 and 9 s, were found, respectively, between 2-3, 1.5-3 and 6 kg/t ds. Both polymers have shown faster water removal with more permeable sludge. SRF values were 0.634 × 10¹², 0.932 × 10¹² and 2 × 10¹² m/kg for Sed CF802, chitosan and FeCl₃respectively. A reduction of 94.68 and 87.85% of the filtrate turbidity was obtained with optimal dosage of chitosan and Sed CF802, respectively. In contrast, 54.18% of turbidity abatement has been obtained using optimal dosage of FeCl₃.
Equilibrium sampling to determine the thermodynamic potential for bioaccumulation of persistent organic pollutants from sediment.

PubMed

Jahnke, Annika; MacLeod, Matthew; Wickström, Håkan; Mayer, Philipp

2014-10-07

Equilibrium partitioning (EqP) theory is currently the most widely used approach for linking sediment pollution by persistent hydrophobic organic chemicals to bioaccumulation. Most applications of the EqP approach assume (I) a generic relationship between organic carbon-normalized chemical concentrations in sediments and lipid-normalized concentrations in biota and (II) that bioaccumulation does not induce levels exceeding those expected from equilibrium partitioning. Here, we demonstrate that assumption I can be obviated by equilibrating a silicone sampler with chemicals in sediment, measuring chemical concentrations in the silicone, and applying lipid/silicone partition ratios to yield concentrations in lipid at thermodynamic equilibrium with the sediment (CLip⇌Sed). Furthermore, we evaluated the validity of assumption II by comparing CLip⇌Sed of selected persistent, bioaccumulative and toxic pollutants (polychlorinated biphenyls (PCBs) and hexachlorobenzene (HCB)) to lipid-normalized concentrations for a range of biota from a Swedish background lake. PCBs in duck mussels, roach, eel, pikeperch, perch and pike were mostly below the equilibrium partitioning level relative to the sediment, i.e., lipid-normalized concentrations were ≤CLip⇌Sed, whereas HCB was near equilibrium between biota and sediment. Equilibrium sampling allows straightforward, sensitive and precise measurement of CLip⇌Sed. We propose CLip⇌Sed as a metric of the thermodynamic potential for bioaccumulation of persistent organic chemicals from sediment useful to prioritize management actions to remediate contaminated sites.
Influence of late-life exposure to environmental enrichmentor exercise on hippocampal function and CA1 senescent physiology

PubMed Central

Kumar, A.; Rani, A.; Tchigranova, Olga; Lee, Wei-Hua; Foster, T.C.

2011-01-01

Aged (20–22 months) male Fischer 344 rats were randomly assigned to sedentary (A-SED), environmentally enriched (A-ENR) or exercise (A-EX) conditions. After 10–12 weeks of differential experience, the three groups of aged rats and young sedentary controls were tested for physical and cognitive function. Spatial discrimination learning and memory consolidation, tested on the water maze, were enhanced in A-ENR compared to A-SED. A-EX exhibited improved and impaired performance on the cue and spatial task, respectively. Impaired spatial learning in A-EX was likely due to a bias in response selection associated with exercise training, as object recognition memory improved for A-EX rats. An examination of senescent hippocampal physiology revealed that enrichment and exercise reversed age-related changes in long-term depression (LTD) and long-term potentiation (LTP). Rats in the enrichment group exhibited an increase in cell excitability compared to the other two groups of aged animals. The results indicate that differential experience biased the selection of a spatial or a response strategy and factors common across the two conditions, such as increased hippocampal activity associated with locomotion, contribute to reversal of senescent synaptic plasticity. PMID:21820213
Science and Engineering Doctorate Awards: 1998.

ERIC Educational Resources Information Center

Hill, Susan T.

The data presented in this report shows trends in doctorate awards by science and engineering (S&E) field and recipient characteristics, institutions awarding doctorates, and postgraduation plans of recipients. The source of the data is the Survey of Earned Doctorates (SED). The SED has been conducted annually for the National Science Foundation…
Science and Engineering Doctorate Awards: 1999.

ERIC Educational Resources Information Center

Hill, Susan T.

The data in this report show trends in doctorate awards by science and engineering (S&E) field and recipient characteristics, institutions awarding doctorates, and postgraduation plans of recipients. The source of the data is the Survey of Earned Doctorates (SED). The SED is conducted annually for the National Science Foundation (NSF) and four…
Relative Prevalence and Correlates of Depressive Characteristics among Seriously Emotionally Disturbed and Nonhandicapped Students.

ERIC Educational Resources Information Center

Cullinan, Douglas; And Others

1987-01-01

The study assessed 237 seriously emotionally disturbed (SED) students and 577 nondisabled students (ages 6-18) on measures of depression, hyperactivity, social status, intelligence, school placement, and aspects of educational achievement. SED students showed greater depression than the nondisabled sample. Patterns of intercorrelations were…
Evaluation of Wraparound Services for Severely Emotionally Disturbed Youths

ERIC Educational Resources Information Center

Mears, Susan L.; Yaffe, Joanne; Harris, Norma J.

2009-01-01

Objectives: Services to children and adolescents with a severe emotional disturbance (SED) have long been inadequate. The wraparound approach has emerged as a promising practice that could address the needs of children with SED and their families through a strength-based, individualized, family-focused team process that emphasizes flexible service…

Estimation of daily mean air temperature from satellite derived radiometric data

NASA Technical Reports Server (NTRS)

Phinney, D.

1976-01-01

The Screwworm Eradication Data System (SEDS) at JSC utilizes satellite derived estimates of daily mean air temperature (DMAT) to monitor the effect of temperature on screwworm populations. The performance of the SEDS screwworm growth potential predictions depends in large part upon the accuracy of the DMAT estimates.
VizieR Online Data Catalog: Coefficients for passband extinctions (Sale+, 2015)

NASA Astrophysics Data System (ADS)

Sale, S. E.; Magorrian, J.

2017-11-01

We have considered how one should measure the distance and extinction to individual stars for use in constructing extinction maps of the whole Galaxy. We advocate the use of monochromatic extinctions, since, unlike bandpass measures such as AV and E(B-V), monochromatic extinctions are linear functions of the dust column density and are independent of the source SED. In particular we suggest the use of A4000, the monochromatic extinction at 4000Å because of its insensitivity to the dust grain size distribution. Files for converting from A_4000 to passband extinctions at 35 RV extinction law value and for 11 photometric systems. (2 data files).
A Herschel-SPIRE Survey of the MonR2 Giant Molecular Cloud

NASA Astrophysics Data System (ADS)

Pokhrel, Riwaj; Gutermuth, Robert; Ali, Babar; Megeath, Thomas; Pipher, Judith; Myers, Philip; Fischer, William; Henning, Thomas; Wolk, Scott; Allen, Lori; Tobin, John

2015-08-01

We present a new survey of the MonR2 giant molecular cloud with SPIRE on the Herschel Space Observatory. We cross-calibrated SPIRE data with Planck-HFI and accounted for its absolute offset and zero point correction. We fixed emissivity with the help of flux-error and flux ratio plots. As the best representation of cold dusty molecular clouds, we did greybody fits of the SEDs. We studied the nature of distribution of column densities above and below certain critical limit, followed by the mass and temperature distributions for different regions. We used dendrograms as a technique to study the hierarchical structures in the GMC.
Infrared-faint radio sources remain undetected at far-infrared wavelengths. Deep photometric observations using the Herschel Space Observatory

NASA Astrophysics Data System (ADS)

Herzog, A.; Norris, R. P.; Middelberg, E.; Spitler, L. R.; Leipski, C.; Parker, Q. A.

2015-08-01

Context. Showing 1.4 GHz flux densities in the range of a few to a few tens of mJy, infrared-faint radio sources (IFRS) are a type of galaxy characterised by faint or absent near-infrared counterparts and consequently extreme radio-to-infrared flux density ratios up to several thousand. Recent studies showed that IFRS are radio-loud active galactic nuclei (AGNs) at redshifts ≳2, potentially linked to high-redshift radio galaxies (HzRGs). Aims: This work explores the far-infrared emission of IFRS, providing crucial information on the star forming and AGN activity of IFRS. Furthermore, the data enable examining the putative relationship between IFRS and HzRGs and testing whether IFRS are more distant or fainter siblings of these massive galaxies. Methods: A sample of six IFRS was observed with the Herschel Space Observatory between 100 μm and 500 μm. Using these results, we constrained the nature of IFRS by modelling their broad-band spectral energy distribution (SED). Furthermore, we set an upper limit on their infrared SED and decomposed their emission into contributions from an AGN and from star forming activity. Results: All six observed IFRS were undetected in all five Herschel far-infrared channels (stacking limits: σ = 0.74 mJy at 100 μm, σ = 3.45 mJy at 500 μm). Based on our SED modelling, we ruled out the following objects to explain the photometric characteristics of IFRS: (a) known radio-loud quasars and compact steep-spectrum sources at any redshift; (b) starburst galaxies with and without an AGN and Seyfert galaxies at any redshift, even if the templates were modified; and (c) known HzRGs at z ≲ 10.5. We find that the IFRS analysed in this work can only be explained by objects that fulfil the selection criteria of HzRGs. More precisely, IFRS could be (a) known HzRGs at very high redshifts (z ≳ 10.5); (b) low-luminosity siblings of HzRGs with additional dust obscuration at lower redshifts; (c) scaled or unscaled versions of Cygnus A at any redshift; and (d) scaled and dust-obscured radio-loud quasars or compact steep spectrum sources. We estimated upper limits on the infrared luminosity, the black hole accretion rate, and the star formation rate of IFRS, which all agreed with corresponding numbers of HzRGs. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.
Spatially resolving the dust properties and submillimetre excess in M 33

NASA Astrophysics Data System (ADS)

Relaño, M.; De Looze, I.; Kennicutt, R. C.; Lisenfeld, U.; Dariush, A.; Verley, S.; Braine, J.; Tabatabaei, F.; Kramer, C.; Boquien, M.; Xilouris, M.; Gratier, P.

2018-05-01

Context. The relative abundance of the dust grain types in the interstellar medium is directly linked to physical quantities that trace the evolution of galaxies. Because of the poor spatial resolution of the infrared and submillimetre data, we are able to study the dependence of the resolved infrared spectral energy distribution (SED) across regions of the interstellar medium (ISM) with different physical properties in just a few objects. Aims: We aim to study the dust properties of the whole disc of M 33 at spatial scales of 170 pc. This analysis allows us to infer how the relative dust grain abundance changes with the conditions of the ISM, study the existence of a submillimetre excess and look for trends of the gas-to-dust mass ratio (GDR) with other physical properties of the galaxy. Methods: For each pixel in the disc of M 33 we have fitted the infrared SED using a physically motivated dust model that assumes an emissivity index β close to two. We applied a Bayesian statistical method to fit the individual SEDs and derived the best output values from the study of the probability density function of each parameter. We derived the relative amount of the different dust grains in the model, the total dust mass, and the strength of the interstellar radiation field (ISRF) heating the dust at each spatial location. Results: The relative abundance of very small grains tends to increase, and for big grains to decrease, at high values of Hα luminosity. This shows that the dust grains are modified inside the star-forming regions, in agreement with a theoretical framework of dust evolution under different physical conditions. The radial dependence of the GDR is consistent with the shallow metallicity gradient observed in this galaxy. The strength of the ISRF derived in our model correlates with the star formation rate in the galaxy in a pixel by pixel basis. Although this is expected, it is the first time that a correlation between the two quantities has been reported. We have produced a map of submillimetre excess in the 500 μm SPIRE band for the disc of M 33. The excess can be as high as 50% and increases at large galactocentric distances. We further studied the relation of the excess with other physical properties of the galaxy and find that the excess is prominent in zones of diffuse ISM outside the main star-forming regions, where the molecular gas and dust surface density are low.
DOE Office of Scientific and Technical Information (OSTI.GOV)

Ade, P. A. R.; Aghanim, N.; Alves, M. I. R.

In this paper, we present all-sky modelling of the high resolution Planck, IRAS, and WISE infrared (IR) observations using the physical dust model presented by Draine & Li in 2007 (DL, ApJ, 657, 810). We study the performance and results of this model, and discuss implications for future dust modelling. The present work extends the DL dust modelling carried out on nearby galaxies using Herschel and Spitzer data to Galactic dust emission. We employ the DL dust model to generate maps of the dust mass surface density Σ Md, the dust optical extinction A V, and the starlight intensity heatingmore » the bulk of the dust, parametrized by U min. The DL model reproduces the observed spectral energy distribution (SED) satisfactorily over most of the sky, with small deviations in the inner Galactic disk and in low ecliptic latitude areas, presumably due to zodiacal light contamination. In the Andromeda galaxy (M31), the present dust mass estimates agree remarkably well (within 10%) with DL estimates based on independent Spitzer and Herschel data. We compare the DL optical extinction A V for the diffuse interstellar medium (ISM) with optical estimates for approximately 2 × 10 5 quasi-stellar objects (QSOs) observed inthe Sloan Digital Sky Survey (SDSS). The DL A V estimates are larger than those determined towards QSOs by a factor of about 2, which depends on U min. The DL fitting parameter U min, effectively determined by the wavelength where the SED peaks, appears to trace variations in the far-IR opacity of the dust grains per unit A V, and not only in the starlight intensity. These results show that some of the physical assumptions of the DL model will need to be revised. To circumvent the model deficiency, we propose an empirical renormalization of the DL A V estimate, dependent of U min, which compensates for the systematic differences found with QSO observations. This renormalization, made to match the A V estimates towards QSOs, also brings into agreement the DL A V estimates with those derived for molecular clouds from the near-IR colours of stars in the 2 micron all sky survey (2MASS). The DL model and the QSOs data are also used to compress the spectral information in the Planck and IRAS observations for the diffuse ISM to a family of 20 SEDs normalized per A V, parameterized by U min, which may be used to test and empirically calibrate dust models. Finally, the family of SEDs and the maps generated with the DL model are made public in the Planck Legacy Archive.« less
Modeling sedimentation-filtration basins for urban watersheds using Soil and Water Assessment Tool

USDA-ARS?s Scientific Manuscript database

Sedimentation-filtration (SedFil) basins are one of the storm-water best management practices (BMPs) that are intended to mitigate water quality problems in urban creeks and rivers. A new physically based model of variably saturated flows was developed for simulating flow and sediment in SedFils wi...
Serious Emotional Disturbance among Youths Exposed to Hurricane Katrina 2 Years Postdisaster

ERIC Educational Resources Information Center

McLaughlin, Katie A.; Fairbank, John A.; Gruber, Michael J.; Jones, Russell T.; Lakoma, Matthew D.; Pfefferbaum, Betty; Sampson, Nancy A.; Kessler, Ronald C.

2009-01-01

Objective: To estimate the prevalence of serious emotional disturbance (SED) among children and adolescents exposed to Hurricane Katrina along with the associations of SED with hurricane-related stressors, sociodemographics, and family factors 18 to 27 months after the hurricane. Method: A probability sample of prehurricane residents of areas…
Temperament Influences on Parenting and Child Psychopathology: Socio-Economic Disadvantage as Moderator

ERIC Educational Resources Information Center

Flouri, Eirini

2008-01-01

Despite calls for research on how the socio-economic environment may be related to temperament, we still do not know enough about the relationship between temperament and socio-economic disadvantage (SED). A particularly under-researched question in temperament research is how SED may moderate the temperament-parenting and the temperament-child…
15 CFR 740.15 - Aircraft and vessels (AVS).

Code of Federal Regulations, 2014 CFR

2014-01-01

... Automated Export System (AES) record is filed in accordance with the requirements of the Foreign Trade Statistics Regulations (15 CFR part 30), except that an SED or AES record is not required when any of the...'s Export Declaration (SED) or Automated Export System (AES) record is filed in accordance with the...
15 CFR 740.15 - Aircraft and vessels (AVS).

Code of Federal Regulations, 2012 CFR

2012-01-01

... Automated Export System (AES) record is filed in accordance with the requirements of the Foreign Trade Statistics Regulations (15 CFR part 30), except that an SED or AES record is not required when any of the...'s Export Declaration (SED) or Automated Export System (AES) record is filed in accordance with the...
15 CFR 740.15 - Aircraft and vessels (AVS).

Code of Federal Regulations, 2013 CFR

2013-01-01

... Automated Export System (AES) record is filed in accordance with the requirements of the Foreign Trade Statistics Regulations (15 CFR part 30), except that an SED or AES record is not required when any of the...'s Export Declaration (SED) or Automated Export System (AES) record is filed in accordance with the...
Service Coordination and Children's Functioning in a School-Based Intensive Mental Health Program

ERIC Educational Resources Information Center

Puddy, Richard W.; Roberts, Michael C.; Vernberg, Eric M.; Hambrick, Erin P.

2012-01-01

Coordination of mental health services in children with serious emotional disturbance (SED) has shown a preliminary relationship to positive outcomes in children. Yet, research in this area is sparse. Therefore, the relation between service coordination activities and adaptive functioning was examined for 51 children SED who were treated in the…
Students with Serious Emotional Disturbance. A Legal Guide to Identification.

ERIC Educational Resources Information Center

Eberharter-Maki, Elaine; And Others

This manual provides guidance to Idaho school districts in identifying students with serious emotional disturbances (SED), as defined by federal and state laws and regulations. Sections 1, 2, and 3 of the guide describe SED in the context of various factors, including the Individuals with Disabilities Education Act, Section 504 of the…
What Attracts High-Achieving Socioeconomically Disadvantaged Students to the Physical Sciences and Engineering?

ERIC Educational Resources Information Center

Conrad, Sarah; Canetto, Silvia Sara; MacPhee, David; Farro, Samantha

2009-01-01

Socioeconomically disadvantaged (SED) students are less likely to major in physical sciences or engineering. To guide recruitment and retention of a diversity of talent, this study examined what attracts high-achieving SED students to these fields. Participants were 50 undergraduates majoring in physical sciences or engineering enrolled in the…
Assessment Practices of School Psychologists When Identifying Children for SED Classes.

ERIC Educational Resources Information Center

Strelnieks, Maija; Wessel, Joan

This study investigated the procedures used by psychologists in a large midwestern urban area for the initial diagnosis and placement of elementary children with severe emotional disturbance (SED) in educational programs in light of the widespread criticism of the use of projective tests due to the questionable reliability of the tests and…
GOSSIP, a New VO Compliant Tool for SED Fitting

NASA Astrophysics Data System (ADS)

Franzetti, P.; Scodeggio, M.; Garilli, B.; Fumana, M.; Paioro, L.

2008-08-01

We present GOSSIP (Galaxy Observed-Simulated SED Interactive Program), a new tool developed to perform SED fitting in a simple, user friendly and efficient way. GOSSIP automatically builds-up the observed SED of an object (or a large sample of objects) combining magnitudes in different bands and eventually a spectrum; then it performs a χ^2 minimization fitting procedure versus a set of synthetic models. The fitting results are used to estimate a number of physical parameters like the Star Formation History, absolute magnitudes, stellar mass and their Probability Distribution Functions. User defined models can be used, but GOSSIP is also able to load models produced by the most commonly used synthesis population codes. GOSSIP can be used interactively with other visualization tools using the PLASTIC protocol for communications. Moreover, since it has been developed with large data sets applications in mind, it will be extended to operate within the Virtual Observatory framework. GOSSIP is distributed to the astronomical community from the PANDORA group web site (http://cosmos.iasf-milano.inaf.it/pandora/gossip.html).
The seed factor: how a combination of four observables can unveil the location of blazar GeV emission.

NASA Astrophysics Data System (ADS)

Harvey, Adam; Georganopoulos, Markos; Meyer, Eileen

2018-01-01

We present here a method for constraining the emission location of γ-rays in powerful, lined blazars (i.e., flat spectrum radio quasars (FSRQs)). We develop a diagnostic criteria, which we term the seed factor, to differentiate between γ-ray emission due to external Compton (EC) scattering in the broad line region (BLR) and the molecular torus (MT). The seed factor is determined entirely by four observable quantities; the synchrotron and inverse Compton (IC) peak frequencies, and the respective peak luminosities. It may thus be possible to use the seed factor to constrain the emission location in a model-independent way.We also present preliminary results of our analysis regarding the seed factor in quasi-simultaneous multi-wavelength SEDs from the Fermi LAT Bright AGN Sample (LBAS), historical data from the ASDC SED Builder of FSRQs in the the Monitoring Of Jets in Active galactic nuclei with VLBA Experiments (MOJAVE) sample, and quasi-simultaneous multi-wavelength SEDs from the Dynamic SEDs of southern blazars (DSSB) sample.
Average radio spectral energy distribution of highly star-forming galaxies

NASA Astrophysics Data System (ADS)

Tisanić, K.; Smolčić, V.; Delhaize, J.; Novak, M.; Intema, H.; Delvecchio, I.; Schinnerer, E.; Zamorani, G.

2018-05-01

The infrared-radio correlation (IRRC) offers a way to assess star formation from radio emission. Multiple studies found the IRRC to decrease with increasing redshift. This may in part be due to the lack of knowledge about the possible radio spectral energy distributions (SEDs) of star-forming galaxies. We constrain the radio SED of a complete sample of highly star-forming galaxies (SFR > 100 M⊙/ yr) based on the VLA-COSMOS 1.4 GHz Joint and 3 GHz Large Project catalogs. We reduce archival GMRT 325 MHz and 610 MHz observations, broadening the rest-frame frequency range to 0.3-15 GHz. Employing survival analysis and fitting a double power law SED, we find that the slope steepens from a spectral index of α1 = 0.51+/-0.04 below 4.5 GHz to α2 = 0.98+/-0.07 above 4.5 GHz. Our results suggest that the use of a K-correction assuming a single power-law radio SED for star forming galaxies is likely not the root cause of the IRRC trend.
Time-Resolved SEDs of Blazars Flares

NASA Astrophysics Data System (ADS)

Kreikenbohm, A.; Dorner, D.; Kadler, M.; Beuchert, T.; Kreter, M.; Kreykenbohm, I.; Langejahn, M.; Leiter, K.; Mannheim, K.; Wilms, J.

2017-10-01

The origin of very-high-energy gamma rays in active galactic nuclei is still under debate. While snapshots of spectral energy distributions (SEDs) can usually be explained with simple competing models, the true emission mechanisms may be revealed from dynamic SED studies during exceptional source states. Based on the FACT monitoring program, we have set up a multiwavelength target-of-opportunity program which allows us to measure time-resolved SEDs during blazar flares. While the FACT and Fermi measurements cover the high energy peak continuously, X-ray observations with INTEGRAL and XMM-Newton are triggered in case of a bright flare. To distinguish orphan flares from time lags between the energy bands, this is combined with an X-ray monitoring with the Swift satellite. In December 2015, observations of the X-ray telescopes Swift and INTEGRAL were triggered during a moderately-high flux state of the TeV blazar Mrk 421. Pre- and post observations in X-rays are available from Swift-XRT. In this presentation, the results from the Mrk 421 ToO observations will be summarized.

Panchromatic Calibration of Astronomical Observations with State-of-the-Art White Dwarf Model Atmospheres

NASA Astrophysics Data System (ADS)

Rauch, T.

2016-05-01

Theoretical spectral energy distributions (SEDs) of white dwarfs provide a powerful tool for cross-calibration and sensitivity control of instruments from the far infrared to the X-ray energy range. Such SEDs can be calculated from fully metal-line blanketed NLTE model-atmospheres that are e.g. computed by the Tübingen NLTE Model-Atmosphere Package (TMAP) that has arrived at a high level of sophistication. TMAP was successfully employed for the reliable spectral analysis of many hot, compact post-AGB stars. High-quality stellar spectra obtained over a wide energy range establish a data base with a large number of spectral lines of many successive ions of different species. Their analysis allows to determine effective temperatures, surface gravities, and element abundances of individual (pre-)white dwarfs with very small error ranges. We present applications of TMAP SEDs for spectral analyses of hot, compact stars in the parameter range from (pre-) white dwarfs to neutron stars and demonstrate the improvement of flux calibration using white-dwarf SEDs that are e.g. available via registered services in the Virtual Observatory.
SED Alumni---breeding ground for scientists

NASA Astrophysics Data System (ADS)

Bederson, Benjamin

2006-04-01

In 1943 the US Army established the Special Engineering Detachment (SED), in which mostly drafted young soldiers possessing some scientific credentials (though usually quite minimal) were reassigned from other duties to the Manhattan Project to assist in various research and development aspects of nuclear weapons. The Los Alamos contingent, never more than a few hundred GIs, worked with more senior scientists and engineers, often assuming positions of real responsibility. An unintended consequence of this circumstance was the fact that being in the SEDs turned out to be a fortuitous breeding ground for future physicists, chemists, and engineers. SEDs benefited from their close contacts with established scientists, working with them side by side, attended lectures by luminaries, and gained invaluable experience that would help them establish academic and industrial careers later in life. I will discuss some of these individuals (I list only those of whom I am personally aware). These include Henry ``Heinz'' Barschall*, Richard Bellman*-RAND Corporation, Murray Peshkin-ANL, Peter Lax-Courant Institute, NYU, William Spindel*-NRC,NAS, Bernard Waldman- Notre Dame, Richard Davisson*-U of Washington, Arnold Kramish- RAND, UNESCO, Josef Hofmann- Acoustic Research Corp, Val Fitch- Princeton U. *deceased
Contemporaneous broadband observations of three high-redshift BL Lac objects

DOE PAGES

Ackerman, M.

2016-03-20

We have collected broadband spectral energy distributions (SEDs) of three BL Lac objects, 3FGL J0022.1-1855 (z=0.689), 3FGL J0630.9-2406 (z > ~1.239), and 3FGL J0811.2-7529 (z=0.774), detected by Fermi with relatively flat GeV spectra. By observing simultaneously in the near-IR to hard X-ray band, we can well characterize the high end of the synchrotron component of the SED. Thus, fitting the SEDs to synchro-Compton models of the dominant emission from the relativistic jet, we can constrain the underlying particle properties and predict the shape of the GeV Compton component. Standard extragalactic background light (EBL) models explain the high-energy absorption well, withmore » poorer fits for high UV models. The fits show clear evidence for EBL absorption in the Fermi spectrum of our highest redshift source 3FGL J0630.9-2406. While synchrotron self-Compton models adequately describe the SEDs, the situation may be complicated by possible external Compton components.« less
Emitting electron spectra and acceleration processes in the jet of PKS 0447-439

NASA Astrophysics Data System (ADS)

Zhou, Yao; Yan, Dahai; Dai, Benzhong; Zhang, Li

2014-02-01

We investigate the electron energy distributions (EEDs) and the corresponding acceleration processes in the jet of PKS 0447-439, and estimate its redshift through modeling its observed spectral energy distribution (SED) in the frame of a one-zone synchrotron-self Compton (SSC) model. Three EEDs formed in different acceleration scenarios are assumed: the power-law with exponential cut-off (PLC) EED (shock-acceleration scenario or the case of the EED approaching equilibrium in the stochastic-acceleration scenario), the log-parabolic (LP) EED (stochastic-acceleration scenario and the acceleration dominating), and the broken power-law (BPL) EED (no acceleration scenario). The corresponding fluxes of both synchrotron and SSC are then calculated. The model is applied to PKS 0447-439, and modeled SEDs are compared to the observed SED of this object by using the Markov Chain Monte Carlo method. The results show that the PLC model fails to fit the observed SED well, while the LP and BPL models give comparably good fits for the observed SED. The results indicate that it is possible that a stochastic acceleration process acts in the emitting region of PKS 0447-439 and the EED is far from equilibrium (acceleration dominating) or no acceleration process works (in the emitting region). The redshift of PKS 0447-439 is also estimated in our fitting: z = 0.16 ± 0.05 for the LP case and z = 0.17 ± 0.04 for BPL case.
UV to IR Luminosities and Dust Attenuation Determined from ~4000 K-selected Galaxies at 1 < z < 3 in the ZFOURGE Survey

NASA Astrophysics Data System (ADS)

Forrest, Ben; Tran, Kim-Vy H.; Tomczak, Adam R.; Broussard, Adam; Labbé, Ivo; Papovich, Casey; Kriek, Mariska; Allen, Rebecca J.; Cowley, Michael; Dickinson, Mark; Glazebrook, Karl; van Houdt, Josha; Inami, Hanae; Kacprzak, Glenn G.; Kawinwanichakij, Lalitwadee; Kelson, Daniel; McCarthy, Patrick J.; Monson, Andrew; Morrison, Glenn; Nanayakkara, Themiya; Persson, S. Eric; Quadri, Ryan F.; Spitler, Lee R.; Straatman, Caroline; Tilvi, Vithal

2016-02-01

We build a set of composite galaxy spectral energy distributions (SEDs) by de-redshifting and scaling multi-wavelength photometry from galaxies in the ZFOURGE survey, covering the CDFS, COSMOS, and UDS fields. From a sample of ˜4000 Ks-band selected galaxies, we define 38 composite galaxy SEDs that yield continuous low-resolution spectra (R ˜ 45) over the rest-frame range 0.1-4 μm. Additionally, we include far infrared photometry from the Spitzer Space Telescope and the Herschel Space Observatory to characterize the infrared properties of our diverse set of composite SEDs. From these composite SEDs we analyze the rest-frame UVJ colors, as well as the ratio of IR to UV light (IRX) and the UV slope (β) in the IRX-β dust relation at 1 < z < 3. Blue star-forming composite SEDs show IRX and β values consistent with local relations; dusty star-forming galaxies have considerable scatter, as found for local IR bright sources, but on average appear bluer than expected for their IR fluxes. We measure a tight linear relation between rest-frame UVJ colors and dust attenuation for star-forming composites, providing a direct method for estimating dust content from either (U - V) or (V-J) rest-frame colors for star-forming galaxies at intermediate redshifts. This paper includes data gathered with the 6.5 m Magellan Telescopes located at Las Campanas Observatory, Chile.
Influence of arterial wave reflection on carotid blood pressure and intima-media thickness in older endurance trained men and women with pre-hypertension.

PubMed

Heffernan, Kevin S; Jae, Sae Young; Tomayko, Emily; Ishaque, Muhammad R; Fernhall, Bo; Wilund, Kenneth R

2009-05-01

Increased carotid intima-media thickness (IMT) with aging is a significant predictor of mortality. Older endurance trained (ET) individuals have lower carotid artery stiffness but similar carotid IMT when compared to sedentary (SED) age-matched peers. The purpose of this study was to examine the contribution of arterial wave reflections to carotid hemodynamics and IMT in older ET and SED with pre-hypertension. Subjects consisted of endurance-trained master athletes and age-matched sedentary controls (mean age 67 years). Carotid artery Beta-stiffness index and IMT was assessed with ultrasonography. Carotid pressure and augmented pressure from wave reflections (obtained from pulse contour analysis) was measured with applanation tonometry. Carotid systolic blood pressure (SBP) and IMT were not different between groups (P>0.05). Carotid stiffness was significantly lower in ET versus SED (7.3 +/- 0.8 versus 9.9 +/- 0.6, P<0.05). Augmented pressure was significantly greater in ET versus SED (17.7 +/- 1.6 versus 13.3 +/- 1.5 mmHg, P<0.05). When adjusting for differences in resting heart rate, there were no group differences in augmented pressure. In conclusion, older ET persons with pre-hypertension have reduced carotid artery stiffness, but similar carotid SBP and carotid IMT when compared to SED. The lack of change in carotid SBP and IMT in older ET may be related to the inability of chronic exercise training to reduce bradycardia-related augmented pressure from wave reflections with aging.
Estimated UV doses to psoriasis patients during climate therapy at Gran Canaria in March 2006

NASA Astrophysics Data System (ADS)

Nilsen, L. T. N.; Søyland, E.; Krogstad, A. L.

2008-01-01

Psoriasis is a chronic inflammatory disease involving about 2-3% of the Norwegian population. Sun exposure has a positive effect on most psoriasis lesions, but ultraviolet (UV) radiation also causes a direct DNA damage in the skin cells and comprises a carcinogenic potential. UV exposure on the skin causes a local as well as a systemic immune suppressive effect, but the relation between sun exposure and these biological effects is not well known. In March 2006 a study was carried out to investigate possible therapeutic outcome mechanisms in 20 psoriasis patients receiving climate therapy at Gran Canaria. This paper presents estimates of their individual skin UV-doses based on UV measurements and the patients' diaries with information on time spent in the sun. On the first day of exposure the patients received on average 5.1 Standard Erythema Doses (SED: median=4.0 SED, range 2.6-10.3 SED) estimated to the skin. During the 15 days study they received 165.8 SED (range 104.3-210.1 SED). The reduction in PASI score was 72.8% on average, but there was no obvious relation between the improvement and the UV dose. The UV doses were higher than those found from climate therapy studies at other locations. It seems beneficial to use more strict exposure schedules that consider the available UV irradiance, depending on time of the day, time of the year and weather conditions.
Levetiracetam is associated with decrease in subclinical epileptiform discharges and improved cognitive functions in pediatric patients with autism spectrum disorder.

PubMed

Wang, Minjian; Jiang, Li; Tang, Xiaoju

2017-01-01

Subclinical epileptiform discharges (SEDs) are common in pediatric patients with autism spectrum disorder (ASD), but the effect of antiepileptic drugs on SEDs in ASD remains inconclusive. This physician-blinded, prospective, randomized controlled trial investigated an association between the anticonvulsant drug levetiracetam and SEDs in children with ASD. A total of 70 children with ASD (4-6 years) and SEDs identified by electroencephalogram were randomly divided into two equal groups to receive either levetiracetam and educational training (treatment group) or educational training only (control). At baseline and after 6 months treatment, the following scales were used to assess each individual's behavioral and cognitive functions: the Chinese version of the Psychoeducational Profile - third edition (PEP-3), Childhood Autism Rating Scale (CARS), and Autism Behavior Checklist (ABC). A 24-hour electroencephalogram was recorded on admission (baseline) and at follow-up. The degree of satisfaction of each patient was also evaluated. Relative to baseline, at the 6-month follow-up, the PEP-3, CARS, and ABC scores were significantly improved in both the treatment and control groups. At the 6-month follow-up, the PEP-3 scores of the treatment group were significantly higher than those of the control, whereas the CARS and ABC scores were significantly lower, and the rate of electroencephalographic normalization was significantly higher in the treatment group. Levetiracetam appears to be effective for controlling SEDs in pediatric patients with ASD and was also associated with improved behavioral and cognitive functions.
Preparation of zein nanoparticles by using solution-enhanced dispersion with supercritical CO2 and elucidation with computational fluid dynamics

PubMed Central

Li, Sining; Zhao, Yaping

2017-01-01

Nanoparticles have attracted more and more attention in the medicinal field. Zein is a biomacromolecule and can be used as a carrier for delivering active ingredients to prepare controlled release drugs. In this article, we presented the preparation of zein nanoparticles by solution-enhanced dispersion by supercritical CO2 (SEDS) approach. Scanning electron microscopy and transmission electron microscopy were applied to characterize the size and morphology of the obtained particles. The nozzle structure and the CO2 flow rate greatly affected the morphology and the size of the particles. The size of zein was able to be reduced to 50–350 nm according to the different conditions. The morphologies of the resultant zein were either sphere or the filament network consisted of nanoparticles. The influence of the nozzle structure and the CO2 flow rate on the velocity field was elucidated by using computational fluid dynamics. The nozzle structure and the CO2 flow rate greatly affected the distribution of the velocity field. However, a similar velocity field could also be obtained when the nozzle structure or the CO2 flow rate, or both were different. Therefore, the influence of the nozzle structure and the CO2 flow rate on the size and morphology of the particles, can boil down to the velocity field. The results demonstrated that the velocity field can be a potential criterion for producing nanoparticles with controllable morphology and size, which is useful to scale-up the SEDS process. PMID:28496324
Investigating Clinical Benefits of a Novel Sleep-Focused Mind-Body Program on Gulf War Illness Symptoms: A Randomized Controlled Trial.

PubMed

Nakamura, Yoshio; Lipschitz, David L; Donaldson, Gary W; Kida, Yuri; Williams, Samuel L; Landward, Richard; Glover, Don W; West, Gavin; Tuteja, Ashok K

Mind-Body Bridging (MBB) has been shown to be effective for improving disturbed sleep. In this prospective randomized controlled trial, we evaluated the efficacy of sleep-focused MBB compared with sleep education control (SED) for improving sleep in previously deployed Gulf War veterans. US military service members with sleep and physical health complaints who were deployed in 1990-1991 were randomized to receive three weekly sessions of either MBB (n = 33) or SED (n = 27) between 2012 and 2015. The primary outcome of Medical Outcomes Study Sleep Scale was completed at baseline, weekly during treatment, postintervention, and 3-month follow-up. Secondary outcome measures for posttraumatic stress disorder, depression, fatigue, quality of life, symptom severity, and mindfulness were completed at baseline, postintervention and 3-month follow-up. Salivary samples were collected at five time points per day at each visit for cortisol and α-amylase assessment. Clinician-administered assessments of sleep and co-occurring conditions were conducted at baseline and postintervention. MBB was significantly more efficacious than SED in reducing disturbed sleep at follow-up (F(1,180.54) = 4.04, p = .046). In addition, self-reported posttraumatic stress disorder (F(1,56.42) = 4.50, p = .038) for the treatment effect, depression (F(1,93.70) = 4.44, p = .038), and fatigue symptoms (F(1,68.58) = 3.90, p = .050) at follow-up improved in MBB compared with those in SED. Consistently higher percentages of veterans in MBB reported improvements of sleep, pain, and composite sleep/general co-occurring symptoms at the postclinical evaluation, as compared with veterans in SED. Finally, the mean waking level of salivary α-amylase in the MBB declined to a greater extent than that in the SED, at follow-up (F(1,88.99) = 3.78, p = .055), whereas no effects were found on cortisol. Sleep-focused MBB can improve sleep and possibly also co-occurring symptoms in Gulf War veterans. Clinicaltrials.gov, NCT01543997.
Effects of voluntary running exercise on bone histology in type 2 diabetic rats.

PubMed

Takamine, Yuri; Ichinoseki-Sekine, Noriko; Tsuzuki, Takamasa; Yoshihara, Toshinori; Naito, Hisashi

2018-01-01

The incidence of obesity in children and adolescents, which may lead to type 2 diabetes, is increasing. Exercise is recommended to prevent and improve diabetes. However, little is known about the bone marrow environment at the onset of diabetes in the young, and it is unclear whether exercise training is useful for maintaining bone homeostasis, such as mechanical and histological properties. Thus, this study clarified the histological properties of bone and whether exercise contributes to maintaining bone homeostasis at the onset of type 2 diabetes in rats. Four-week-old male Otsuka Long-Evans Tokushima Fatty (OLETF; n = 21) rats as a diabetic model and Long-Evans Tokushima Otsuka (LETO; n = 18) rats as a control were assigned randomly to four groups: the OLETF sedentary group (O-Sed; n = 11), OLETF exercise group (O-Ex; n = 10), LETO sedentary group (L-Sed; n = 9), and LETO exercise group (L-Ex; n = 9). All rats in the exercise group were allowed free access to a steel running wheel for 20 weeks (5-25 weeks of age). In the glucose tolerance test, blood glucose level was higher in the O-Sed group than that in the L-Sed and L-Ex groups, and was markedly suppressed by the voluntary running exercise of O-Ex rats. The energy to fracture and the two-dimensional bone volume at 25 weeks of age did not differ significantly among the groups, though the maximum breaking force and stiffness were lower in OLETF rats. However, bone marrow fat volume was greater in O-Sed than that in L-Sed and L-Ex rats, and was markedly suppressed by wheel running in the O-Ex rats. Our results indicate that exercise has beneficial effects not only for preventing diabetes but also on normal bone remodeling at an early age.
DirtyGrid I: 3D Dust Radiative Transfer Modeling of Spectral Energy Distributions of Dusty Stellar Populations

NASA Astrophysics Data System (ADS)

Law, Ka-Hei; Gordon, Karl D.; Misselt, Karl A.

2018-06-01

Understanding the properties of stellar populations and interstellar dust has important implications for galaxy evolution. In normal star-forming galaxies, stars and the interstellar medium dominate the radiation from ultraviolet (UV) to infrared (IR). In particular, interstellar dust absorbs and scatters UV and optical light, re-emitting the absorbed energy in the IR. This is a strongly nonlinear process that makes independent studies of the UV-optical and IR susceptible to large uncertainties and degeneracies. Over the years, UV to IR spectral energy distribution (SED) fitting utilizing varying approximations has revealed important results on the stellar and dust properties of galaxies. Yet the approximations limit the fidelity of the derived properties. There is sufficient computer power now available that it is now possible to remove these approximations and map out of landscape of galaxy SEDs using full dust radiative transfer. This improves upon previous work by directly connecting the UV, optical, and IR through dust grain physics. We present the DIRTYGrid, a grid of radiative transfer models of SEDs of dusty stellar populations in galactic environments designed to span the full range of physical parameters of galaxies. Using the stellar and gas radiation input from the stellar population synthesis model PEGASE, our radiative transfer model DIRTY self-consistently computes the UV to far-IR/sub-mm SEDs for each set of parameters in our grid. DIRTY computes the dust absorption, scattering, and emission from the local radiation field and a dust grain model, thereby physically connecting the UV-optical to the IR. We describe the computational method and explain the choices of parameters in DIRTYGrid. The computation took millions of CPU hours on supercomputers, and the SEDs produced are an invaluable tool for fitting multi-wavelength data sets. We provide the complete set of SEDs in an online table.
Chronic aerobic swimming exercise promotes functional and morphological changes in rat ileum

PubMed Central

da Cunha Araujo, Layanne Cabral; de Souza, Iara Leão Luna; Vasconcelos, Luiz Henrique César; de Freitas Brito, Aline; Queiroga, Fernando Ramos; Silva, Alexandre Sérgio; da Silva, Patrícia Mirella; de Andrade Cavalcante, Fabiana; da Silva, Bagnólia Araújo

2015-01-01

Several studies have reported the gastrointestinal (GI) effects promoted by the physical exercise. Thus, we aimed to evaluate the influence of swimming exercise on the contractile reactivity, lipid peroxidation and morphology of rat ileum. Wistar rats were divided into sedentary (SED) and groups exercised for two (EX2), four (EX4), six (EX6) or eight (EX8) weeks, 5 days/week. Animals were killed; the ileum was removed and suspended in organ baths where the isotonic contractions were recorded. Lipid peroxidation was evaluated by MDA (malondialdehyde) measurement with TBARS (thiobarbituric acid reactive substances) assay and morphology by histological staining. Cumulative concentration-response curves to KCl were attenuated, as the Emax values were changed from 100% (SED) to 63.1±3.9 (EX2), 48.8±3.8 (EX4), 19.4±1.8 (EX6) and 59.4±2.8% (EX8). Similarly, cumulative concentration-response curves to carbamylcholine hydrochloride (CCh) were attenuated, as the Emax values were changed from 100% (SED) to 74.1±5.4 (EX2), 75.9±5.2 (EX4) and 62.9±4.6 (EX6), but not in the EX8 (89.7±3.4%). However, CCh potency was increased in this latter, as the EC50 was altered from 1.0±0.1×10−6 (SED) to 2.1±0.4×10−7 (EX8). MDA concentration was altered only in EX4 (44.3±4.4) compared with SED (20.6±3.6 μmol/l). Circular layer was reduced in SED when compared with the exercised groups. Conversely, longitudinal layer was increased. In conclusion, chronic swimming exercise reduces the ileum contraction, equilibrates the oxidative damage and promotes changes in tissue size to establish an adaptation to the exercise. PMID:26424698
Effects of semielemental diet containing whey peptides on Peyer's patch lymphocyte number, immunoglobulin A levels, and intestinal morphology in mice.

PubMed

Moriya, Tomoyuki; Fukatsu, Kazuhiko; Noguchi, Midori; Nishikawa, Makoto; Miyazaki, Hiromi; Saitoh, Daizoh; Ueno, Hideki; Yamamoto, Junji

2018-02-01

Enteral nutrition (EN) is the gold standard of nutritional therapy for critically ill or severely injured patients, because EN promotes gut and hepatic immunity, thereby preventing infectious complications as compared with parenteral nutrition. However, there are many EN formulas with different protein and fat contents. Their effects on gut-associated lymphoid tissue remain unclear. Recently, semielemental diets (SEDs) containing whey peptides as a nitrogen source have been found to be beneficial in patients with malabsorption or pancreatitis. Herein, we examined the influences of various dietary formulations on gut immunity to clarify the advantages of SEDs over elemental diets. Forty-four male Institute of Cancer Research mice were randomized to four groups: chow (CH: n = 5), intragastric total parenteral nutrition (IG-TPN: n = 13), elemental diet (ED: n = 13), and SED (n = 13). The CH group received CH diet ad libitum, whereas the IG-TPN, ED (Elental, Ajinomoto, Japan), and SED (Peptino, Terumo, Japan) groups were given their respective diets for 5 day via gastrostomy. After 5 days, the mice were killed to obtain whole small intestines. Peyer's patch (PP) lymphocytes were harvested and counted. Their subpopulations were evaluated by flow cytometry. Immunoglobulin A (IgA) levels in intestinal and respiratory tract washings were measured with enzyme-linked immunosorbent assay. Villous height (VH) and crypt depth in the distal intestine were measured by light microscopy. SED increased the PP cell number and intestinal or respiratory IgA levels to those of CH mice, while ED partially restored these parameters. The IG-TPN group showed the lowest PP cell number and IgA levels among the four groups. VH was significantly greater in the CH than in the other groups. VH in the ED and SED groups also exceeded in the IG-TPN group, while being similar in these two groups. No significant crypt depth differences were observed among the four groups. SED administration can be recommended for patients unable tolerate complex enteral diets or a normal diet in terms of not only absorption and tolerability but also maintenance of gut immunity. Copyright © 2017 Elsevier Inc. All rights reserved.
SED-dependent galactic extinction prescription for Euclid and future cosmological surveys

NASA Astrophysics Data System (ADS)

Galametz, Audrey; Saglia, Roberto; Paltani, Stéphane; Apostolakos, Nikolaos; Dubath, Pierre

2017-02-01

The outcome of upcoming cosmological surveys will depend on the accurate estimates of photometric redshifts. In the framework of the implementation of the photometric redshift algorithm for the ESA Euclid mission, we are exploring new avenues to improve current template-fitting methods. This paper focusses in particular on the prescription of the extinction of a source light by dust in the Milky Way. Since Galactic extinction strongly correlates with wavelength and photometry is commonly obtained through broad-band filters, the amount of absorption depends on the source intrinsic spectral energy distribution (SED), a point however neglected as the source SED is not known a-priori. A consequence of this dependence is that the observed EB-V (=AB-AV) will in general be different from the EB-V used to normalise the Galactic absorption law kλ (=Aλ/EB-V). Band-pass corrections are thus required to adequately renormalise the law for a given SED. In this work, we assess the band-pass corrections of a range of SEDs and find they vary by up to 20%. We have investigated how neglecting these corrections biases the calibration of dust into reddening map and how the scaling of the map depends of the sources used for its calibration. We derive dust-to-reddening scaling factors from the colour excesses of z< 0.4 SDSS red galaxies and show that band-pass corrections predict the observed differences. Extinction corrections are then estimated for a range of SEDs and a set of optical to near-infrared filters relevant to Euclid and upcoming cosmological ground-based surveys. For high extinction line-of-sights (EB-V> 0.1, 8% of the Euclid Wide survey), the variations in corrections can be up to 0.1 mag in the "bluer" optical filters (ugr) and up to 0.04 mag in the near-infrared filters. We find that an inaccurate correction of Galactic extinction critically affects photometric redshift estimates. In particular, for high extinction lines of sights and z < 0.5, the bias (I.e. the mean Δz = zphot-zreal) exceeds 0.2%(1 + z), the precision required for weak-lensing analyses. Additional uncertainty on the parametrisation of the Milky Way extinction curve itself further reduces the photometric redshift precision. We propose a new prescription of Galactic absorption for template-fitting algorithms which takes into consideration the dependence of extinction with SED.
Spectroscopic infrared extinction mapping as a probe of grain growth in IRDCs

NASA Astrophysics Data System (ADS)

Lim, Wanggi; Carey, Sean J.

2014-07-01

We present photometric and spectroscopic tests of MIR to FIR extinction laws toward IRDC G028.36+00.07, a potential site of massive star formation. Lim & Tan (2014, hereafter LT14) developed methods of FIR extinction mapping of this source using Spitzer-MIPS 24 micron and Herschel-PACS 70 micron images, and extending the MIR 8 micron mapping methods of (Butler & Tan 2012, hereafter BT12), finding evidence for grain growth in the highest mass surface density regions. Here we present initial results of spectroscopic infrared extinction (SIREX) mapping using Spitzer-IRS (14 to 38 micron) data of the same IRDC. These methods allow us to measure the SED of the diffuse Galactic ISM, which we compare to theoretical models of Draine & Li (2007), as well as to search for opacity law variations with mass surface density within the IRDC. By comparison with theoretical dust models, e.g., Ossenkopf & Henning (1994) and Ormel et al. (2011), we are able to search for compositional signatures of the grain ices, such as water and methanol. We find evidence for generally flatter MIR to FIR extinction laws as mass surface density increases, strengthening the evidence for grain and ice mantle growth in higher density regions.
Selenium supplementation has beneficial and detrimental effects on immunity to influenza vaccine in older adults.

PubMed

Ivory, Kamal; Prieto, Elena; Spinks, Caroline; Armah, Charlotte N; Goldson, Andrew J; Dainty, Jack R; Nicoletti, Claudio

2017-04-01

Mortality resulting from influenza (flu) virus infections occurs primarily in the elderly through declining immunity. Studies in mice have suggested beneficial effects of selenium (Se) supplementation on immunity to flu but similar evidence is lacking in humans. A dietary intervention study was therefore designed to test the effects of Se-supplementation on a variety of parameters of anti-flu immunity in healthy subjects aged 50-64 years. A 12-week randomized, double-blinded, placebo-controlled clinical trial (ClinicalTrials.govNCT00279812) was undertaken in six groups of individuals with plasma Se levels <110 ng/mL. Four groups were given daily capsules of yeast enriched with 0 μg Se/day (SeY-0/d; n = 20), 50 μg Se/d (SeY-50/d; n = 18), 100 μg Se/d (SeY-100/d; n = 21) or 200 μg Se/d (SeY-200/d; n = 23). Two groups were given onion-containing meals with either <1 μg Se/d (SeO-0/d; n = 17) or 50 μg Se/d (SeO-50/d; n = 18). Flu vaccine was administrated at week 10 and immune parameters were assessed until week 12. Primary study endpoints were changes in cellular and humoral immune responses. Supplementation with SeY and SeO affected different aspects of cellular immunity. SeY increased Tctx-ADCC cell counts in blood (214%, SeY-100/d) before flu vaccination and a dose-dependent increase in T cell proliferation (500%, SeY-50/100/200/d), IL-8 (169%, SeY-100/d) and IL-10 (317%, SeY-200/d) secretion after in vivo flu challenge. Positive effects were contrasted by lower granzyme B content of CD8 cells (55%, SeY-200/d). SeO (Se 50 μg/d) also enhanced T cell proliferation after vaccination (650%), IFN-γ (289%), and IL-8 secretion (139%), granzyme (209%) and perforin (190%) content of CD8 cells but inhibited TNF-α synthesis (42%). Onion on its own reduced the number of NKT cells in blood (38%). These effects were determined by comparison to group-specific baseline yeast or onion control groups. Mucosal flu-specific antibody responses were unaffected by Se-supplementation. Se-supplementation in healthy human adults with marginal Se status resulted in both beneficial and detrimental effects on cellular immunity to flu that was affected by the form of Se, supplemental dose and delivery matrix. These observations call for a thorough evaluation of the risks and benefits associated with Se-supplementation. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.
Reporting of Violent and Disruptive Incidents by Public Schools. Report 2005-S-38

ERIC Educational Resources Information Center

New York State Education Department, 2006

2006-01-01

The objective of this report was to determine whether the State Education Department (SED) has developed effective processes for (1) ensuring that school districts report violent and disruptive incidents to SED in accordance with State law and regulations, (2) identifying schools that should be designated as persistently dangerous because of their…
Dose-Effect of Children's Psychosocial Rehabilitation on the Daily Functioning of Youth with Serious Emotional Disturbance

ERIC Educational Resources Information Center

Williams, Nathaniel J.

2009-01-01

Children's psychosocial rehabilitation (CPSR) is a promising but under-evaluated home- and community-based treatment for children with serious emotional disturbance (SED). CPSR addresses the functional impairments of children with SED through an asset-based, skill-building approach that involves multiple systems in the child's life. The present…
Combining the Bourne-Shell, sed and awk in the UNIX Environment for Language Analysis.

ERIC Educational Resources Information Center

Schmitt, Lothar M.; Christianson, Kiel T.

This document describes how to construct tools for language analysis in research and teaching using the Bourne-shell, sed, and awk, three search tools, in the UNIX operating system. Applications include: searches for words, phrases, grammatical patterns, and phonemic patterns in text; statistical analysis of text in regard to such searches,…

The spectral energy distributions of the entire Herschel Reference Survey

NASA Astrophysics Data System (ADS)

Ciesla, Laure

2012-08-01

We present the spectral energy distributions (SED) of the 323 galaxies of the Herschel Reference Survey. In order to provide templates for nearby galaxies calibrated on physical parameters, we computed mean SEDs per bin of morphological types and stellar masses. They will be very useful to study more distant galaxies and their evolution with redshift. This preliminary work aims to study how the most commonly used libraries (Chary & Elbaz 2001, Dale & Helou 2002 and Draine & Li 2007) reproduce the far-infrared emission of galaxies. First results show that they reproduce well the far-infrared part of mean SEDs. For single galaxies the Draine & Li (2007) models seem to reproduce very well the far-infrared emission, as does the Dale & Helou (2002).
IS THE LINE-LIKE OPTICAL AFTERGLOW SED OF GRB 050709 DUE TO A FLARE?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Cong; Jin, Zhi-Ping; Wei, Da-Ming, E-mail: jin@pmo.ac.cn

Recently, Jin et al. reanalyzed the optical observation data of GRB 050709 and reported a line-like spectral energy distribution (SED) component observed by the Very Large Telescope at t ∼ 2.5 days after the trigger of the burst, which had been interpreted as a broadened line signal arising from a macronova dominated by an iron group. In this work, we show that an optical flare origin of such a peculiar optical SED is still possible. Interestingly, even in such a model, an “unusual” origin of the late-time long-lasting Hubble Space Telescope F 814 W -band emission is still needed and a macronova/kilonovamore » is the natural interpretation.« less
Autophagy activation, not peroxisome proliferator-activated receptor γ coactivator 1α, may mediate exercise-induced improvements in glucose handling during diet-induced obesity.

PubMed

Rosa-Caldwell, Megan E; Brown, Jacob L; Lee, David E; Blackwell, Thomas A; Turner, Kyle W; Brown, Lemuel A; Perry, Richard A; Haynie, Wesley S; Washington, Tyrone A; Greene, Nicholas P

2017-09-01

What is the central question of this study? What are the individual and combined effects of muscle-specific peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) overexpression and physical activity during high-fat feeding on glucose and exercise tolerance? What is the main finding and its importance? Our main finding is that muscle-specific PGC-1α overexpression provides no protection against lipid-overload pathologies nor does it enhance exercise adaptations. Instead, physical activity, regardless of PGC-1α content, protects against high-fat diet-induced detriments. Activation of muscle autophagy was correlated with exercise protection, suggesting that autophagy might be a mediating factor for exercise-induced protection from lipid overload. The prevalence of glucose intolerance is alarmingly high. Efforts to promote mitochondrial biogenesis through peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) to mitigate glucose intolerance have been controversial. However, physical activity remains a primary means to alleviate the condition. The aim of this study was to determine the combined effects of muscle-specific overexpression of PGC-1α and physical activity on glucose handling during diet-induced obesity. Wild-type (WT, ∼20) and PGC-1α muscle transgenic (MCK-PGC-1α, ∼20) mice were given a Western diet (WD) at 8 weeks age and allowed to consume food ab libitum throughout the study. At 12 weeks of age, all animals were divided into sedentary (SED) or voluntary wheel running (VWR) interventions. At 7, 11 and 15 weeks of age, animals underwent glucose tolerance tests (GTT) and graded exercise tests (GXT). At 16 weeks of age, tissues were collected. At 11 weeks, the MCK-PGC-1α animals had 50% greater glucose tolerance integrated area under the curve compared with WT. However, at 15 weeks, SED animals also had greater GTT integrated area under the curve compared with VWR, regardless of genotype; furthermore, SED animals demonstrated reduced exercise capacity compared with earlier time points, which was not seen in VWR animals. Voluntary distance run per day was correlated with GTT in VWR-WT, but not VWR-MCK-PGC-1α mice. Voluntary wheel running and genotype independently resulted in a greater LC3II/LC3I ratio, suggesting enhanced autophagosome formation, which was correlated with exercise-induced improvements in GTT. In conclusion, artificially increasing mitochondrial content does not protect from lipid-induced pathologies nor does it augment exercise adaptations. Physical activity ameliorates the effects of lipid overload-induced glucose intolerance, an effect that appears to be related to enhanced activation of autophagy. © 2017 The Authors. Experimental Physiology © 2017 The Physiological Society.
[Numeric simulation of functional remodeling of the anterior alveolar bone].

PubMed

Wang, Wei-feng; Xin, Hai-tao; Zang, Shun-lai; Ding, Jie

2012-04-01

To study the remodeling of the anterior alveolar bone with parodontium under physiology loading using finite element method (FEM) and theory of bone remodeling. A FEM model of the maxillary central incisor with parodontium was established, and the change of bone density during the remodeling of alveolar bone was investigated under physiology loading (60 - 150 N) based on the theory of bone remodeling about strain energy density (SED). The finite element analysis software Abaqus user material subroutine (UMAT) were used. With the increase of physiology loading, the pressure stress on the buccal cervical margin increased gradually while the density was decreased gradually. The cortical bone was lower than its initial density 1.74 g/cm(3), which was 1.74 - 1.63 g/cm(3). The density of cancellous bone was 0.90 - 0.77 g/cm(3), which was lower than its intial density 0.90 g/cm(3). The lingual cervical margin was under tensile stress which also increased with loading, the density had no significant change. When the achieve to 120 N, the density of cortical bone was 1.74 - 1.73 g/cm(3). No significant change was found in the cancellous bone. The simulation of the perodontium remodeling is achieved and proved to be effective by the relevant research based on the method of the study. And the result will be helpful to form the basis of analysis bone remodeling process and predict the results in the clinical work.
VizieR Online Data Catalog: Intrinsic far-IR SED of luminous AGNs (Lyu+, 2017)

NASA Astrophysics Data System (ADS)

Lyu, J.; Rieke, G. H.

2018-01-01

The range of currently proposed active galactic nucleus (AGN) far-infrared templates results in uncertainties in retrieving host galaxy information from infrared observations and also undermines constraints on the outer part of the AGN torus. We discuss how to test and reconcile these templates. Physically, the fraction of the intrinsic AGN IR-processed luminosity compared with that from the central engine should be consistent with the dust-covering factor. In addition, besides reproducing the composite spectral energy distributions (SEDs) of quasars, a correct AGN IR template combined with an accurate library of star-forming galaxy templates should be able to reproduce the IR properties of the host galaxies, such as the luminosity-dependent SED shapes and aromatic feature strengths. We develop tests based on these expected behaviors and find that the shape of the AGN intrinsic far-IR emission drops off rapidly starting at ~20μm and can be matched by an Elvis+ (1994, J/ApJS/95/1)-like template with a minor modification. Despite the variations in the near- to mid-IR bands, AGNs in quasars and Seyfert galaxies have remarkably similar intrinsic far-IR SEDs at λ~20-100μm, suggesting a similar emission character of the outermost region of the circumnuclear torus. The variations of the intrinsic AGN IR SEDs among the type-1 quasar population can be explained by the changing relative strengths of four major dust components with similar characteristic temperatures, and there is evidence for compact AGN-heated dusty structures at sub-kiloparsec scales in the far-IR. (3 data files).
Dust-deficient Palomar-Green Quasars and the Diversity of AGN Intrinsic IR Emission

NASA Astrophysics Data System (ADS)

Lyu, Jianwei; Rieke, G. H.; Shi, Yong

2017-02-01

To elucidate the intrinsic broadband infrared (IR) emission properties of active galactic nuclei (AGNs), we analyze the spectral energy distributions (SEDs) of 87 z ≲ 0.5 Palomar-Green (PG) quasars. While the Elvis AGN template with a moderate far-IR correction can reasonably match the SEDs of the AGN components in ˜60% of the sample (and is superior to alternatives such as that by Assef), it fails on two quasar populations: (1) hot-dust-deficient (HDD) quasars that show very weak emission thoroughly from the near-IR to the far-IR, and (2) warm-dust-deficient (WDD) quasars that have similar hot dust emission as normal quasars but are relatively faint in the mid- and far-IR. After building composite AGN templates for these dust-deficient quasars, we successfully fit the 0.3-500 μm SEDs of the PG sample with the appropriate AGN template, an infrared template of a star-forming galaxy, and a host galaxy stellar template. 20 HDD and 12 WDD quasars are identified from the SED decomposition, including seven ambiguous cases. Compared with normal quasars, the HDD quasars have AGNs with relatively low Eddington ratios and the fraction of WDD quasars increases with AGN luminosity. Moreover, both the HDD and WDD quasar populations show relatively stronger mid-IR silicate emission. Virtually identical SED properties are also found in some quasars from z = 0.5 to 6. We propose a conceptual model to demonstrate that the observed dust deficiency of quasars can result from a change of structures of the circumnuclear tori that can occur at any cosmic epoch.
Exercise training improves vascular mitochondrial function

PubMed Central

Park, Song-Young; Rossman, Matthew J.; Gifford, Jayson R.; Bharath, Leena P.; Bauersachs, Johann; Richardson, Russell S.; Abel, E. Dale; Symons, J. David

2016-01-01

Exercise training is recognized to improve cardiac and skeletal muscle mitochondrial respiratory capacity; however, the impact of chronic exercise on vascular mitochondrial respiratory function is unknown. We hypothesized that exercise training concomitantly increases both vascular mitochondrial respiratory capacity and vascular function. Arteries from both sedentary (SED) and swim-trained (EX, 5 wk) mice were compared in terms of mitochondrial respiratory function, mitochondrial content, markers of mitochondrial biogenesis, redox balance, nitric oxide (NO) signaling, and vessel function. Mitochondrial complex I and complex I + II state 3 respiration and the respiratory control ratio (complex I + II state 3 respiration/complex I state 2 respiration) were greater in vessels from EX relative to SED mice, despite similar levels of arterial citrate synthase activity and mitochondrial DNA content. Furthermore, compared with the SED mice, arteries from EX mice displayed elevated transcript levels of peroxisome proliferative activated receptor-γ coactivator-1α and the downstream targets cytochrome c oxidase subunit IV isoform 1, isocitrate dehydrogenase (Idh) 2, and Idh3a, increased manganese superoxide dismutase protein expression, increased endothelial NO synthase phosphorylation (Ser1177), and suppressed reactive oxygen species generation (all P < 0.05). Although there were no differences in EX and SED mice concerning endothelium-dependent and endothelium-independent vasorelaxation, phenylephrine-induced vasocontraction was blunted in vessels from EX compared with SED mice, and this effect was normalized by NOS inhibition. These training-induced increases in vascular mitochondrial respiratory capacity and evidence of improved redox balance, which may, at least in part, be attributable to elevated NO bioavailability, have the potential to protect against age- and disease-related challenges to arterial function. PMID:26825520
DOE Office of Scientific and Technical Information (OSTI.GOV)

Lyu, Jianwei; Rieke, G. H.; Shi, Yong, E-mail: jianwei@email.arizona.edu

To elucidate the intrinsic broadband infrared (IR) emission properties of active galactic nuclei (AGNs), we analyze the spectral energy distributions (SEDs) of 87 z ≲ 0.5 Palomar-Green (PG) quasars. While the Elvis AGN template with a moderate far-IR correction can reasonably match the SEDs of the AGN components in ∼60% of the sample (and is superior to alternatives such as that by Assef), it fails on two quasar populations: (1) hot-dust-deficient (HDD) quasars that show very weak emission thoroughly from the near-IR to the far-IR, and (2) warm-dust-deficient (WDD) quasars that have similar hot dust emission as normal quasars butmore » are relatively faint in the mid- and far-IR. After building composite AGN templates for these dust-deficient quasars, we successfully fit the 0.3–500 μm SEDs of the PG sample with the appropriate AGN template, an infrared template of a star-forming galaxy, and a host galaxy stellar template. 20 HDD and 12 WDD quasars are identified from the SED decomposition, including seven ambiguous cases. Compared with normal quasars, the HDD quasars have AGNs with relatively low Eddington ratios and the fraction of WDD quasars increases with AGN luminosity. Moreover, both the HDD and WDD quasar populations show relatively stronger mid-IR silicate emission. Virtually identical SED properties are also found in some quasars from z = 0.5 to 6. We propose a conceptual model to demonstrate that the observed dust deficiency of quasars can result from a change of structures of the circumnuclear tori that can occur at any cosmic epoch.« less
Levetiracetam is associated with decrease in subclinical epileptiform discharges and improved cognitive functions in pediatric patients with autism spectrum disorder

PubMed Central

Wang, Minjian; Jiang, Li; Tang, Xiaoju

2017-01-01

Objective Subclinical epileptiform discharges (SEDs) are common in pediatric patients with autism spectrum disorder (ASD), but the effect of antiepileptic drugs on SEDs in ASD remains inconclusive. This physician-blinded, prospective, randomized controlled trial investigated an association between the anticonvulsant drug levetiracetam and SEDs in children with ASD. Methods A total of 70 children with ASD (4–6 years) and SEDs identified by electroencephalogram were randomly divided into two equal groups to receive either levetiracetam and educational training (treatment group) or educational training only (control). At baseline and after 6 months treatment, the following scales were used to assess each individual’s behavioral and cognitive functions: the Chinese version of the Psychoeducational Profile – third edition (PEP-3), Childhood Autism Rating Scale (CARS), and Autism Behavior Checklist (ABC). A 24-hour electroencephalogram was recorded on admission (baseline) and at follow-up. The degree of satisfaction of each patient was also evaluated. Results Relative to baseline, at the 6-month follow-up, the PEP-3, CARS, and ABC scores were significantly improved in both the treatment and control groups. At the 6-month follow-up, the PEP-3 scores of the treatment group were significantly higher than those of the control, whereas the CARS and ABC scores were significantly lower, and the rate of electroencephalographic normalization was significantly higher in the treatment group. Conclusion Levetiracetam appears to be effective for controlling SEDs in pediatric patients with ASD and was also associated with improved behavioral and cognitive functions. PMID:28919764
Dust Processing in Supernova Remnants: Spitzer MIPS SED and IRS Observations

NASA Technical Reports Server (NTRS)

Hewitt, John W.; Petre, Robert; Katsuda Satoru; Andersen, M.; Rho, J.; Reach, W. T.; Bernard, J. P.

2011-01-01

We present Spitzer MIPS SED and IRS observations of 14 Galactic Supernova Remnants previously identified in the GLIMPSE survey. We find evidence for SNR/molecular cloud interaction through detection of [OI] emission, ionic lines, and emission from molecular hydrogen. Through black-body fitting of the MIPS SEDs we find the large grains to be warm, 29-66 K. The dust emission is modeled using the DUSTEM code and a three component dust model composed of populations of big grains, very small grains, and polycyclic aromatic hydrocarbons. We find the dust to be moderately heated, typically by 30-100 times the interstellar radiation field. The source of the radiation is likely hydrogen recombination, where the excitation of hydrogen occurred in the shock front. The ratio of very small grains to big grains is found for most of the molecular interacting SNRs to be higher than that found in the plane of the Milky Way, typically by a factor of 2--3. We suggest that dust shattering is responsible for the relative over-abundance of small grains, in agreement with prediction from dust destruction models. However, two of the SNRs are best fit with a very low abundance of carbon grains to silicate grains and with a very high radiation field. A likely reason for the low abundance of small carbon grains is sputtering. We find evidence for silicate emission at 20 $\\mu$m in their SEDs, indicating that they are young SNRs based on the strong radiation field necessary to reproduce the observed SEDs.
Hot Dust in Panchromatic SED Fitting: Identification of Active Galactic Nuclei and Improved Galaxy Properties

NASA Astrophysics Data System (ADS)

Leja, Joel; Johnson, Benjamin D.; Conroy, Charlie; van Dokkum, Pieter

2018-02-01

Forward modeling of the full galaxy SED is a powerful technique, providing self-consistent constraints on stellar ages, dust properties, and metallicities. However, the accuracy of these results is contingent on the accuracy of the model. One significant source of uncertainty is the contribution of obscured AGN, as they are relatively common and can produce substantial mid-IR (MIR) emission. Here we include emission from dusty AGN torii in the Prospector SED-fitting framework, and fit the UV–IR broadband photometry of 129 nearby galaxies. We find that 10% of the fitted galaxies host an AGN contributing >10% of the observed galaxy MIR luminosity. We demonstrate the necessity of this AGN component in the following ways. First, we compare observed spectral features to spectral features predicted from our model fit to the photometry. We find that the AGN component greatly improves predictions for observed Hα and Hβ luminosities, as well as mid-infrared Akari and Spitzer/IRS spectra. Second, we show that inclusion of the AGN component changes stellar ages and SFRs by up to a factor of 10, and dust attenuations by up to a factor of 2.5. Finally, we show that the strength of our model AGN component correlates with independent AGN indicators, suggesting that these galaxies truly host AGN. Notably, only 46% of the SED-detected AGN would be detected with a simple MIR color selection. Based on these results, we conclude that SED models which fit MIR data without AGN components are vulnerable to substantial bias in their derived parameters.
New Design for an Adjustable Cise Space Maintainer

PubMed Central

2018-01-01

Objective The aim of this study is to present a new adjustable Cise space maintainer for preventive orthodontic applications. Methods Stainless steel based new design consists of six main components. In order to understand the major displacement and stress fields, structural analysis for the design is considered by using finite element method. Results Similar to major displacement at y-axis, critical stresses σx and τxy possess a linear distribution with constant increasing. Additionally, strain energy density (SED) plays an important role to determine critical biting load capacity. Conclusion Structural analysis shows that the space maintainer is stable and is used for maintaining and/or regaining the space which arouses early loss of molar tooth. PMID:29854764
A Whole Class Teaching Approach to Improve the Vocabulary Skills of Adolescents Attending Mainstream Secondary School, in Areas of Socioeconomic Disadvantage

ERIC Educational Resources Information Center

Murphy, Aoife; Franklin, Sue; Breen, Annemarie; Hanlon, Molly; McNamara, Aoife; Bogue, Aine; James, Emily

2017-01-01

Young people from areas of socioeconomic disadvantage (SED) are more likely to present with language difficulties, particularly vocabulary difficulties. Studies have shown the effectiveness of vocabulary interventions for children with language impairment but not for adolescents from areas of SED. This article aims to establish the effectiveness…
15 CFR 744.7 - Restrictions on certain exports to and for the use of certain foreign vessels or aircraft.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Export System (AES) record is filed in accordance with the requirements of the Foreign Trade Statistics Regulations (15 CFR part 30), except that an SED or AES record is not required when any of the commodities... as cargo for which a Shipper's Export Declaration (SED) or Automated Export System (AES) record is...
15 CFR 744.7 - Restrictions on certain exports to and for the use of certain foreign vessels or aircraft.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Export System (AES) record is filed in accordance with the requirements of the Foreign Trade Statistics Regulations (15 CFR part 30), except that an SED or AES record is not required when any of the commodities... as cargo for which a Shipper's Export Declaration (SED) or Automated Export System (AES) record is...
15 CFR 744.7 - Restrictions on certain exports to and for the use of certain foreign vessels or aircraft.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Export System (AES) record is filed in accordance with the requirements of the Foreign Trade Statistics Regulations (15 CFR part 30), except that an SED or AES record is not required when any of the commodities... as cargo for which a Shipper's Export Declaration (SED) or Automated Export System (AES) record is...
15 CFR 744.7 - Restrictions on certain exports to and for the use of certain foreign vessels or aircraft.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Export System (AES) record is filed in accordance with the requirements of the Foreign Trade Statistics Regulations (15 CFR part 30), except that an SED or AES record is not required when any of the commodities... as cargo for which a Shipper's Export Declaration (SED) or Automated Export System (AES) record is...
An Animal Model of Active (Act) Versus Sedentary (Sed) Lifestyle and Susceptibility to Air Pollution: Response to Ozone (O3) in Female Sprague-Dawley Rats Allowed to Train Chronically On Running Wheels

EPA Science Inventory

Epidemiological data suggest that a sedentary lifestyle may contribute to increased suseptibility to environmental pollutants. Furthermore, the association between a sedentary pattern and development of obesity may exacerbate susceptibility. To study the effects of ACT vs. SED l...
Exercise training regulates SOD-1 and oxidative stress in porcine aortic endothelium.

PubMed

Rush, James W E; Turk, James R; Laughlin, M Harold

2003-04-01

Vascular oxidative stress contributes to endothelial dysfunction. Aerobic exercise training improves vascular function. The purpose of this study was to test the hypothesis that exercise training would improve the balance of antioxidant to prooxidant enzymes and reduce markers of oxidative stress in aortic endothelial cells (AEC). Female Yucatan miniature pigs either remained sedentary (SED) or were exercise trained (EX) for 16-19 wk. EX pigs had increased AEC SOD-1 protein levels and Cu/Zn SOD activity of the whole aorta compared with SED pigs. Protein levels of other antioxidant enzymes (SOD-2, catalase) were not affected by exercise training. Protein levels of p67(phox), a subunit of the prooxidant enzyme NAD(P)H oxidase, were reduced in EX vs. SED AEC. These EX adaptations were associated with lower AEC malondialdehyde levels and decreased phosphorylation of ERK-1/2. Endothelial nitric oxide synthase protein, protein nitrotyrosine content, and heme oxygenase-1 protein were not different in EX vs. SED pigs. We conclude that chronic aerobic exercise training influenced both antioxidant and prooxidant enzymes and decreased indexes of oxidative stress in AEC. These adaptations may contribute to improved endothelial function with exercise training.
Optimizing Methods of Obtaining Stellar Parameters for the H3 Survey

NASA Astrophysics Data System (ADS)

Ivory, KeShawn; Conroy, Charlie; Cargile, Phillip

2018-01-01

The Stellar Halo at High Resolution with Hectochelle Survey (H3) is in the process of observing and collecting stellar parameters for stars in the Milky Way's halo. With a goal of measuring radial velocities for fainter stars, it is crucial that we have optimal methods of obtaining this and other parameters from the data from these stars.The method currently developed is The Payne, named after Cecilia Payne-Gaposchkin, a code that uses neural networks and Markov Chain Monte Carlo methods to utilize both spectra and photometry to obtain values for stellar parameters. This project was to investigate the benefit of fitting both spectra and spectral energy distributions (SED). Mock spectra using the parameters of the Sun were created and noise was inserted at various signal to noise values. The Payne then fit each mock spectrum with and without a mock SED also generated from solar parameters. The result was that at high signal to noise, the spectrum dominated and the effect of fitting the SED was minimal. But at low signal to noise, the addition of the SED greatly decreased the standard deviation of the data and resulted in more accurate values for temperature and metallicity.

Youth and Caregiver Physical Activity and Sedentary Time: HCHS/SOL Youth.

PubMed

Gallo, Linda C; Roesch, Scott P; McCurley, Jessica L; Isasi, Carmen R; Sotres-Alvarez, Daniela; Delamater, Alan M; Van Horn, Linda; Arredondo, Elva M; Perreira, Krista M; Buelna, Christina; Qi, Qibin; Vidot, Denise C; Carnethon, Mercedes R

2017-01-01

We examined associations between youth and caregiver moderate/ vigorous physical activity (MVPA) and sedentary (SED) time, using accelerometery, in the Hispanic Community Health Study/Study of Latino Youth (HCHS/ SOL) Youth. Participants were 623 caregivers and 877 youth 8-16 years old, enrolled in 2012-2014. Associations of youth and caregiver MVPA time, SED time, and meeting MVPA recommendations ( 150 min/week, adults; 420 min/week, youth) were examined in regression models that controlled for sample weights, design effects, and demographic and health covariates. Youth whose caregivers met MVPA recommendations were nearly twice as likely to meet these recommendations themselves when compared to youth whose caregivers did not meet MVPA recommendations (OR = 1.9, 95 CI 1.1, 3.3). Youth and caregiver SED time also were significantly related (p .05). A similar pattern of findings was observed in analyses limited to relationships in which the caregiver was a biological parent of the youth (N = 485 caregivers; N = 795 youth). MVPA and SED are correlated within Latino families as observed by statistically significant relationships of youth and caregiver activity. Additional research is needed to understand underlying genetic and environmental factors that explain these findings.
The Absolute Magnitude of the Sun in Several Filters

NASA Astrophysics Data System (ADS)

Willmer, Christopher N. A.

2018-06-01

This paper presents a table with estimates of the absolute magnitude of the Sun and the conversions from vegamag to the AB and ST systems for several wide-band filters used in ground-based and space-based observatories. These estimates use the dustless spectral energy distribution (SED) of Vega, calibrated absolutely using the SED of Sirius, to set the vegamag zero-points and a composite spectrum of the Sun that coadds space-based observations from the ultraviolet to the near-infrared with models of the Solar atmosphere. The uncertainty of the absolute magnitudes is estimated by comparing the synthetic colors with photometric measurements of solar analogs and is found to be ∼0.02 mag. Combined with the uncertainty of ∼2% in the calibration of the Vega SED, the errors of these absolute magnitudes are ∼3%–4%. Using these SEDs, for three of the most utilized filters in extragalactic work the estimated absolute magnitudes of the Sun are M B = 5.44, M V = 4.81, and M K = 3.27 mag in the vegamag system and M B = 5.31, M V = 4.80, and M K = 5.08 mag in AB.
On the Jet Properties of γ-Ray-loud Active Galactic Nuclei

NASA Astrophysics Data System (ADS)

Chen, Liang

2018-04-01

Based on broadband spectral energy distributions (SEDs), we estimate the jet physical parameters of 1392 γ-ray-loud active galactic nuclei (AGNs), the largest sample so far. The (SED) jet power and magnetization parameter are derived for these AGNs. Out of these sources, the accretion disk luminosity of 232 sources and (extended) kinetic jet powers of 159 sources are compiled from archived papers. We find the following. (1) Flat-spectrum radio quasars (FSRQs) and BL Lacs are well separated by {{Γ }}=-0.127{log}{L}γ +8.18 in the γ-ray luminosity versus photon index plane with a success rate of 88.6%. (2) Most FSRQs present a (SED) jet power larger than the accretion power, which suggests that the relativistic jet-launching mechanism is dominated by the Blandford–Znajek process. This result confirms previous findings. (3) There is a significant anticorrelation between jet magnetization and a ratio of the (SED) jet power to the (extended) kinetic jet power, which, for the first time, provides supporting evidence for the jet energy transportation theory: a high-magnetization jet may more easily transport energy to a large scale than a low-magnetization jet.
Simulation Experiment Description Markup Language (SED-ML) Level 1 Version 2.

PubMed

Bergmann, Frank T; Cooper, Jonathan; Le Novère, Nicolas; Nickerson, David; Waltemath, Dagmar

2015-09-04

The number, size and complexity of computational models of biological systems are growing at an ever increasing pace. It is imperative to build on existing studies by reusing and adapting existing models and parts thereof. The description of the structure of models is not sufficient to enable the reproduction of simulation results. One also needs to describe the procedures the models are subjected to, as recommended by the Minimum Information About a Simulation Experiment (MIASE) guidelines. This document presents Level 1 Version 2 of the Simulation Experiment Description Markup Language (SED-ML), a computer-readable format for encoding simulation and analysis experiments to apply to computational models. SED-ML files are encoded in the Extensible Markup Language (XML) and can be used in conjunction with any XML-based model encoding format, such as CellML or SBML. A SED-ML file includes details of which models to use, how to modify them prior to executing a simulation, which simulation and analysis procedures to apply, which results to extract and how to present them. Level 1 Version 2 extends the format by allowing the encoding of repeated and chained procedures.
Simulation Experiment Description Markup Language (SED-ML) Level 1 Version 2.

PubMed

Bergmann, Frank T; Cooper, Jonathan; Le Novère, Nicolas; Nickerson, David; Waltemath, Dagmar

2015-06-01

The number, size and complexity of computational models of biological systems are growing at an ever increasing pace. It is imperative to build on existing studies by reusing and adapting existing models and parts thereof. The description of the structure of models is not sufficient to enable the reproduction of simulation results. One also needs to describe the procedures the models are subjected to, as recommended by the Minimum Information About a Simulation Experiment (MIASE) guidelines. This document presents Level 1 Version 2 of the Simulation Experiment Description Markup Language (SED-ML), a computer-readable format for encoding simulation and analysis experiments to apply to computational models. SED-ML files are encoded in the Extensible Markup Language (XML) and can be used in conjunction with any XML-based model encoding format, such as CellML or SBML. A SED-ML file includes details of which models to use, how to modify them prior to executing a simulation, which simulation and analysis procedures to apply, which results to extract and how to present them. Level 1 Version 2 extends the format by allowing the encoding of repeated and chained procedures.
Experimental and environmental factors affect spurious detection of ecological thresholds

USGS Publications Warehouse

Daily, Jonathan P.; Hitt, Nathaniel P.; Smith, David; Snyder, Craig D.

2012-01-01

Threshold detection methods are increasingly popular for assessing nonlinear responses to environmental change, but their statistical performance remains poorly understood. We simulated linear change in stream benthic macroinvertebrate communities and evaluated the performance of commonly used threshold detection methods based on model fitting (piecewise quantile regression [PQR]), data partitioning (nonparametric change point analysis [NCPA]), and a hybrid approach (significant zero crossings [SiZer]). We demonstrated that false detection of ecological thresholds (type I errors) and inferences on threshold locations are influenced by sample size, rate of linear change, and frequency of observations across the environmental gradient (i.e., sample-environment distribution, SED). However, the relative importance of these factors varied among statistical methods and between inference types. False detection rates were influenced primarily by user-selected parameters for PQR (τ) and SiZer (bandwidth) and secondarily by sample size (for PQR) and SED (for SiZer). In contrast, the location of reported thresholds was influenced primarily by SED. Bootstrapped confidence intervals for NCPA threshold locations revealed strong correspondence to SED. We conclude that the choice of statistical methods for threshold detection should be matched to experimental and environmental constraints to minimize false detection rates and avoid spurious inferences regarding threshold location.
Voluntary Running Attenuates Metabolic Dysfunction in Ovariectomized Low-Fit Rats

PubMed Central

Park, Young-Min; Padilla, Jaume; Kanaley, Jill A.; Zidon, Terese; Welly, Rebecca J.; Britton, Steven L.; Koch, Lauren G.; Thyfault, John P.; Booth, Frank W.; Vieira-Potter, Victoria J.

2016-01-01

INTRODUCTION Ovariectomy and high fat diet (HFD) worsen obesity and metabolic dysfunction associated with low aerobic fitness. Exercise training mitigates metabolic abnormalities induced by low aerobic fitness, but whether the protective effect is maintained following ovariectomy and HFD is unknown. PURPOSE This study determined whether, following ovariectomy and HFD, exercise training improves metabolic function in rats bred for low intrinsic aerobic capacity. METHODS Female rats selectively bred for low (LCR) and high (HCR) intrinsic aerobic capacity (n=30) were ovariectomized, fed HFD, and randomized to either a sedentary (SED) or voluntary wheel running (EX) group. Resting energy expenditure, glucose tolerance, and spontaneous physical activity were determined midway through the experiment, while body weight, wheel running volume, and food intake were assessed throughout the study. Body composition, circulating metabolic markers, and skeletal muscle gene and protein expression was measured at sacrifice. RESULTS EX reduced body weight and adiposity in LCR rats (−10% and −50%, respectively; P<0.05) and, unexpectedly, increased these variables in HCR rats (+7% and +37%, respectively; P<0.05) compared to their respective SED controls, likely due to dietary overcompensation. Wheel running volume was ~5-fold greater in HCR than LCR rats, yet EX enhanced insulin sensitivity equally in LCR and HCR rats (P<0.05). This EX-mediated improvement in metabolic function was associated with gene up-regulation of skeletal muscle IL-6&-10. EX also increased resting energy expenditure, skeletal muscle mitochondrial content (oxidative phosphorylation complexes and citrate synthase activity), and AMPK activation similarly in both lines (all P <0.05). CONCLUSION Despite a 5-fold difference in running volume between rat lines, EX similarly improved systemic insulin sensitivity, resting energy expenditure, and skeletal muscle mitochondrial content and AMPK activation in ovariectomized LCR and HCR rats fed HFD compared to their respective SED controls. PMID:27669449
VizieR Online Data Catalog: Type 2 AGN host galaxies in Chandra-COSMOS (Suh+, 2017)

NASA Astrophysics Data System (ADS)

Suh, H.; Civano, F.; Hasinger, G.; Lusso, E.; Lanzuisi, G.; Marchesi, S.; Trakhtenbrot, B.; Allevato, V.; Cappelluti, N.; Capak, P. L.; Elvis, M.; Griffiths, R. E.; Laigle, C.; Lira, P.; Riguccini, L.; Rosario, D. J.; Salvato, M.; Schawinski, K.; Vignali, C.

2018-01-01

We investigate the star formation properties of a large sample of ~2300 X-ray-selected Type 2 Active Galactic Nuclei (AGNs) host galaxies out to z~3 in the Chandra COSMOS Legacy Survey in order to understand the connection between the star formation and nuclear activity. Making use of the existing multi-wavelength photometric data available in the COSMOS field, we perform a multi-component modeling from far-infrared to near-ultraviolet using a nuclear dust torus model, a stellar population model and a starburst model of the spectral energy distributions (SEDs). Through detailed analyses of SEDs, we derive the stellar masses and the star formation rates (SFRs) of Type 2 AGN host galaxies. The stellar mass of our sample is in the range of 93), and grow slowly through secular fueling processes hosting moderate-luminosity AGNs. (1 data file).
Two Methods for Retrieving UV Index for All Cloud Conditions from Sky Imager Products or Total SW Radiation Measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Badosa, Jordi; Calbo, J.; McKenzie, R. L.

2014-07-01

In the present study, we assess the cloud effects on UV Index (UVI) and total solar radiation (TR) as a function of cloud cover estimations and sunny conditions (from sky imaging products) as well as of solar zenith angle (SZA). These analyses are undertaken for a southern-hemisphere mid-latitude site where a 10-years dataset is available. It is confirmed that clouds reduce TR more than UV, in particular for obscured Sun conditions, low cloud fraction (< 60%) and large SZA (> 60º). Similarly, clouds enhance TR more than UV, mainly for visible Sun conditions, large cloud fraction and large SZA. Twomore » methods to estimate UVI are developed: 1) from sky imaging cloud cover and sunny conditions, and 2) from TR measurements. Both methods may be used in practical operational applications, although Method 2 shows overall the best performance, since TR allows accounting for cloud optical properties. The mean absolute differences of Method 2 estimations with respect to measured values are 0.17 UVI units (for 1-minute data) and 0.79 Standard Erythemal Dose (SED) units (for daily integrations). Method 1 shows less accurate results but it is still suitable to estimate UVI: mean absolute differences are 0.37 UVI units and 1.6 SED.« less
Effects of continuous low-carbohydrate diet after long-term exercise on GLUT-4 protein content in rat skeletal muscle.

PubMed

Kubota, M; Koshinaka, K; Kawata, Y; Koike, T; Oshida, Y

2008-01-01

Stimulation of AMPK and decreased glycogen levels in skeletal muscle have a deep involvement in enhanced insulin action and GLUT-4 protein content after exercise training. The present study examined the chronic effects of a continuous low-carbohydrate diet after long-term exercise on GLUT-4 protein content, glycogen content, AMPK, and insulin signaling in skeletal muscle. Rats were divided randomly into four groups: normal chow diet sedentary (N-Sed), low carbohydrate diet sedentary (L-Sed), normal chow diet exercise (N-Ex), and low carbohydrate diet exercise (L-Ex) groups. Rats in the exercise groups (N-Ex and L-Ex) were exercised by swimming for 6 hours/day in two 3-hour bouts separated by 45 minutes of rest. The 10-day exercise training resulted in a significant increase in the GLUT-4 protein content (p<0.01). Additionally, the GLUT-4 protein content in L-Ex rats was increased by 29% above that in N-Ex rats (p<0.01). Finally, the glycogen content in skeletal muscle of L-Ex rats was decreased compared with that of N-Ex rats. Taken together, we suggest that the maintenance of glycogen depletion after exercise by continuous low carbohydrate diet results in the increment of the GLUT-4 protein content in skeletal muscle.
ALMA Observations of the Galactic Center: SiO Outflows and High Mass Star Formation Near Sgr A

NASA Technical Reports Server (NTRS)

Yusef-Zadeh, F.; Royster, M.; Wardle, M.; Arendt, R.; Bushouse, H.; Gillessen, S.; Lis, D.; Pound, M. W.; Roberts, D. A.; Whitney, B.;

2013-01-01

Using ALMA observations of the Galactic center with a spatial resolution of 2.61" x 0.97 ", we detected 11 SiO (5-4) clumps of molecular gas in the within 0.6pc (15") of Sgr A*, interior of the 2-pc circumnuclear molecular ring. Three SiO (5-4) clumps closest to Sgr A* show the largest central velocities of approximately 150 kilometers per second and broadest asymmetric linewidths with total linewidths FWZI approximately 110-147 kilometers per second. Other clumps are distributed mainly to the NE of the ionized minispiral with narrow linewidths of FWHM approximately 11-27 kilometers per second. Using CARMA data, LVG modeling of the broad velocity clumps, the SiO (5-4) and (2-1) line ratios constrain the column density N(SiO) approximately 10(exp 14) per square centimeter, and the H2 gas density n(sub H2) = (3-9) x 10(exp 5) per cubic centimeter for an assumed kinetic temperature 100-200K. The SiO (5-4) clumps with broad and narrow linewidths are interpreted as highly embedded protostellar outflows, signifying an early stage of massive star formation near Sgr A* in the last 104 years. Additional support for the presence of YSO outflows is that the luminosities and velocity widths lie in the range detected from protostellar outflows in star forming regions in the Galaxy. Furthermore, SED modeling of stellar sources along the N arm show two YSO candidates near SiO clumps supporting in-situ star formation near Sgr A*. We discuss the nature of star formation where the gravitational potential of the black hole dominates. In particular, we suggest that external radiative pressure exerted on self-shielded molecular clouds enhance the gas density, before the gas cloud become gravitationally unstable near Sgr A*.

Advance and application of the stratigraphic simulation model 2D- SedFlux: From tank experiment to geological scale simulation

NASA Astrophysics Data System (ADS)

Kubo, Yu'suke; Syvitski, James P. M.; Hutton, Eric W. H.; Paola, Chris

2005-07-01

The stratigraphic simulation model 2D- SedFlux is further developed and applied to a turbidite experiment in a subsiding minibasin. The new module dynamically simulates evolving hyperpycnal flows and their interaction with the basin bed. Comparison between the numerical results and the experimental results verifies the ability of 2D- SedFlux to predict the distribution of the sediments and the possible feedback from subsidence. The model was subsequently applied to geological-scale minibasins such as are located in the Gulf of Mexico. Distance from the sediment source is determined to be more influential than the sediment entrapment in upstream minibasin. The results suggest that efficiency of sediment entrapment by a basin was not influenced by the distance from the sediment source.
Bioavailability of particle-associated Se to the bivalve Potamocorbula amurensis

USGS Publications Warehouse

Schlekat, C.E.; Dowdle, P.R.; Lee, B.-G.; Luoma, S.N.; Oremland, R.S.

2000-01-01

Elemental selenium, Se(0), is a prevalent chemical form in sediments, but little is known about its bioavailability. We evaluated the bioavailability of two forms of Se(0) by generating radioisotopic 75Se(0) through bacterial dissimilatory reduction of 75SeO32- by pure bacterial cultures (SES) and by an anaerobic sediment microbial consortium (SED). A third form was generated by reducing 75SeO32- with ascorbic acid (AA). Speciation determinations showed that AA and SES were >90% Se(0), but SED showed a mixture of Se(0), selenoanions, and a residual fraction. Pulse-chase techniques were used to measure assimilation efficiencies (AE) of these particulate Se forms by the bivalve Potamocorbula amurensis. Mean AE values were 3 ?? 2% for AA, 7 ?? 1% for SES, and 28 ?? 15% for SED, showing that the bioavailability of reduced, particle-associated Se is dependent upon its origin. To determine if oxidative microbial processes increased Se transfer, SES 75Se(0) was incubated with an aerobic sediment microbial consortium. After 113 d of incubation, 36% of SES Se(0) was oxidized to SeO32-. Assimilation of total particulate Se was unaffected however (mean AE = 5.5%). The mean AE from the diatom Phaeodactylum tricornutum was 58 ?? 8%, verifying the importance of Se associated with biogenic particles. Speciation and AE results from SED suggest that selenoanion reduction in wetlands and estuaries produces biologically available reduced selenium.Elemental selenium, Se(0), is a prevalent chemical form in sediments, but little is known about its bioavailability. We evaluated the bioavailability of two forms of Se(0) by generating radioisotopic 75Se(0) through bacterial dissimilatory reduction of 75SeO32- by pure bacterial cultures (SES) and by an anaerobic sediment microbial consortium (SED). A third form was generated by reducing 75SeO32 with ascorbic acid (AA). Speciation determinations showed that AA and SES were > 90% Se(0), but SED showed a mixture of Se(0), selenoanions, and a residual fraction. Pulse-chase techniques were used to measure assimilation efficiencies (AE) of these particulate Se forms by the bivalve Potamocorbula amurensis. Mean AE values were 3 ?? 2% for AA, 7 ?? 1% for SES, and 28 ?? 15% for SED, showing that the bioavailability of reduced, particle-associated Se is dependent upon its origin. To determine if oxidative microbial processes increased Se transfer, SES 75Se(0) was incubated with an aerobic sediment microbial consortium. After 113 d of incubation, 36% of SES Se(0) was oxidized to SeO32-. Assimilation of total particulate Se was unaffected however (mean AE = 5.5%). The mean AE from the diatom Phaeodactylum tricornutum was 58 ?? 8%, verifying the importance of Se associated with biogenic particles. Speciation and AE results from SED suggest that selenoanion reduction in wetlands and estuaries produces biologically available reduced selenium.
Translations on Eastern Europe, Political, Sociological, and Military Affairs, Number 1317

DTIC Science & Technology

1976-11-09

Issue of SED Theoretical Journal Reviewed (Helmut Caspar; NEUES DEUTSCHLAND, 28 Sep 76) 7 Significance of Legislative Election Process...Pando Vanchev fruitful work in the Seventh Five-Year Plan. 5003 CSO: 2200 EAST GERMANY SEPTEMBER 1976 ISSUE OF SED THEORETICAL JOURNAL REVIEWED...imperialist exploitation. Proceeding from the Marxist-Leninist theory of state, we find in the further unfolding of socialist democracy a universal
Doctorate Recipients from U.S. Universities. Summary Report, 2007-08. Survey of Earned Doctorates. Special Report

ERIC Educational Resources Information Center

National Science Foundation, 2009

2009-01-01

"Doctorate Recipients from U.S. Universities: Summary Report 2007-08" is the 41st in a series of reports on research doctorates awarded by universities in the United States. Data presented in this report were collected by the Survey of Earned Doctorates (SED). The SED, which has been conducted annually since 1957, is a census of all…
Appetite control and biomarkers of satiety with vegetarian (soy) and meat-based high-protein diets for weight loss in obese men: a randomized crossover trial.

PubMed

Neacsu, Madalina; Fyfe, Claire; Horgan, Graham; Johnstone, Alexandra M

2014-08-01

There is limited evidence with regard to the effect of different sources of protein on appetite during weight loss. Vegetarian and meat-based high-protein diets may have contrasting effects on appetite and biomarkers of protein-induced satiety. The aim was to assess appetite response to meat or vegetarian high-protein weight-loss (HPWL) diets in obese men to monitor plasma amino acid profile and gut peptide response as potential satiety biomarkers. Twenty obese [body mass index (in kg/m²): 34.8] men participated in a dietary intervention study. After 3 d of a maintenance diet, they were provided in a crossover design with either a vegetarian HPWL (Soy-HPWL) or a meat-based HPWL (Meat-HPWL) diet for 2 wk. Both diets comprised 30% protein, 30% fat, and 40% carbohydrate, provided to measured resting metabolic rate. Body weight and the motivation to eat were measured daily. Plasma satiety biomarkers were collected during a test-meal challenge (5 h) at the end of each diet period. Over the 2 wk, subjects lost, on average, 2.41 and 2.27 kg with consumption of the Soy- and Meat-HPWL diets, respectively [P = 0.352; SE of the difference (SED): 0.1]. ANOVA confirmed that subjectively rated hunger (P = 0.569; SED: 3.8), fullness (P = 0.404; SED: 4.1), desire to eat (P = 0.356; SED: 3.7), preservation of lean body mass (P = 0.334; SED: 0.2), and loss of percentage fat mass (P = 0.179; SED: 0.2) did not differ between the 2 HPWL diets. There were differences in absolute concentrations of ghrelin and peptide YY between the 2 HPWL diets, although the response as net area under the curve was not different. Appetite control and weight loss were similar for both HPWL diets. Gut hormone profile was similar between the diets, which suggests that vegetarian diets can be as effective as meat-based diets for appetite control during weight loss. © 2014 American Society for Nutrition.
The Virtual Observatory Service TheoSSA: Establishing a Database of Synthetic Stellar Flux Standards I. NLTE Spectral Analysis of the DA-Type White Dwarf G191-B2B *,**,***,****

NASA Technical Reports Server (NTRS)

Rauch, T.; Werner, K.; Bohlin, R.; Kruk, J. W.

2013-01-01

Hydrogen-rich, DA-type white dwarfs are particularly suited as primary standard stars for flux calibration. State-of-the-art NLTE models consider opacities of species up to trans-iron elements and provide reliable synthetic stellar-atmosphere spectra to compare with observations. Aims. We will establish a database of theoretical spectra of stellar flux standards that are easily accessible via a web interface. Methods. In the framework of the Virtual Observatory, the German Astrophysical Virtual Observatory developed the registered service TheoSSA. It provides easy access to stellar spectral energy distributions (SEDs) and is intended to ingest SEDs calculated by any model-atmosphere code. In case of the DA white dwarf G191-B2B, we demonstrate that the model reproduces not only its overall continuum shape but also the numerous metal lines exhibited in its ultraviolet spectrum. Results. TheoSSA is in operation and contains presently a variety of SEDs for DA-type white dwarfs. It will be extended in the near future and can host SEDs of all primary and secondary flux standards. The spectral analysis of G191-B2B has shown that our hydrostatic models reproduce the observations best at Teff =60 000 +/- 2000K and log g=7.60 +/- 0.05.We newly identified Fe vi, Ni vi, and Zn iv lines. For the first time, we determined the photospheric zinc abundance with a logarithmic mass fraction of -4.89 (7.5 × solar). The abundances of He (upper limit), C, N, O, Al, Si, O, P, S, Fe, Ni, Ge, and Sn were precisely determined. Upper abundance limits of about 10% solar were derived for Ti, Cr, Mn, and Co. Conclusions. The TheoSSA database of theoretical SEDs of stellar flux standards guarantees that the flux calibration of all astronomical data and cross-calibration between different instruments can be based on the same models and SEDs calculated with different model-atmosphere codes and are easy to compare.
Urban women's socioeconomic status, health service needs and utilization in the four weeks after postpartum hospital discharge: findings of a Canadian cross-sectional survey.

PubMed

Kurtz Landy, Christine; Sword, Wendy; Ciliska, Donna

2008-10-03

Postpartum women who experience socioeconomic disadvantage are at higher risk for poor health outcomes than more advantaged postpartum women, and may benefit from access to community based postpartum health services. This study examined socioeconomically disadvantaged (SED) postpartum women's health, and health service needs and utilization patterns in the first four weeks post hospital discharge, and compared them to more socioeconomically advantaged (SEA) postpartum women's health, health service needs and utilization patterns. Data collected as part of a large Ontario cross-sectional mother-infant survey were analyzed. Women (N = 1000) who had uncomplicated vaginal births of single 'at-term' infants at four hospitals in two large southern Ontario, Canada cities were stratified into SED and SEA groups based on income, social support and a universally administered hospital postpartum risk screen. Participants completed a self-administered questionnaire before hospital discharge and a telephone interview four weeks after discharge. Main outcome measures were self-reported health status, symptoms of postpartum depression, postpartum service needs and health service use. When compared to the SEA women, the SED women were more likely to be discharged from hospital within the first 24 hours after giving birth [OR 1.49, 95% CI (1.01-2.18)], less likely to report very good or excellent health [OR 0.48, 95% CI (0.35-0.67)], and had higher rates of symptoms of postpartum depression [OR 2.7, 95% CI(1.64-4.4)]. No differences were found between groups in relation to self reported need for and ability to access services for physical and mental health needs, or in use of physicians, walk-in clinics and emergency departments. The SED group were more likely to accept public health nurse home visits [OR 2.24, 95% CI(1.47-3.40)]. Although SED women experienced poorer mental and overall health they reported similar health service needs and utilization patterns to more SEA women. The results can assist policy makers, health service planners and providers to develop and implement necessary and accessible services. Further research is needed to evaluate SED postpartum women's health service needs and barriers to service use.
Hyper-luminous dust-obscured galaxies discovered by the Hyper Suprime-Cam on Subaru and WISE

NASA Astrophysics Data System (ADS)

Toba, Yoshiki; Nagao, Tohru; Strauss, Michael A.; Aoki, Kentaro; Goto, Tomotsugu; Imanishi, Masatoshi; Kawaguchi, Toshihiro; Terashima, Yuichi; Ueda, Yoshihiro; Bosch, James; Bundy, Kevin; Doi, Yoshiyuki; Inami, Hanae; Komiyama, Yutaka; Lupton, Robert H.; Matsuhara, Hideo; Matsuoka, Yoshiki; Miyazaki, Satoshi; Morokuma, Tomoki; Nakata, Fumiaki; Oi, Nagisa; Onoue, Masafusa; Oyabu, Shinki; Price, Paul; Tait, Philip J.; Takata, Tadafumi; Tanaka, Manobu M.; Terai, Tsuyoshi; Turner, Edwin L.; Uchida, Tomohisa; Usuda, Tomonori; Utsumi, Yousuke; Yamada, Yoshihiko; Wang, Shiang-Yu

2015-10-01

We present the photometric properties of a sample of infrared (IR) bright dust-obscured galaxies (DOGs). Combining wide and deep optical images obtained with the Hyper Suprime-Cam on the Subaru Telescope and all-sky mid-IR (MIR) images taken with Wide-Field Infrared Survey Explorer, we discovered 48 DOGs with i - Ks > 1.2 and i - [22] > 7.0, where i, Ks, and [22] represent AB magnitude in the i-band, Ks-band, and 22 μm, respectively, in the GAMA 14 hr field (˜ 9 deg2). Among these objects, 31 (˜ 65%) show power-law spectral energy distributions (SEDs) in the near-IR (NIR) and MIR regime, while the remainder show an NIR bump in their SEDs. Assuming that the redshift distribution for our DOGs sample is Gaussian, with mean and sigma z = 1.99 ± 0.45, we calculated their total IR luminosity using an empirical relation between 22 μm luminosity and total IR luminosity. The average value of the total IR luminosity is (3.5 ± 1.1) × 1013 L⊙, which classifies them as hyper-luminous infrared galaxies. We also derived the total IR luminosity function (LF) and IR luminosity density (LD) for a flux-limited subsample of 18 DOGs with 22 μm flux greater than 3.0 mJy and with i-band magnitude brighter than 24 AB magnitude. The derived space density for this subsample is log φ = -6.59 ± 0.11 [Mpc-3]. The IR LF for DOGs including data obtained from the literature is fitted well by a double-power law. The derived lower limit for the IR LD for our sample is ρIR ˜ 3.8 × 107 [L⊙ Mpc-3] and its contributions to the total IR LD, IR LD of all ultra-luminous infrared galaxies, and that of all DOGs are > 3%, > 9%, and > 15%, respectively.
Determining Empirical Stellar Masses and Radii from Transits and Gaia Parallaxes as Illustrated by Spitzer Observations of KELT-11b

NASA Astrophysics Data System (ADS)

Beatty, Thomas G.; Stevens, Daniel J.; Collins, Karen A.; Colón, Knicole D.; James, David J.; Kreidberg, Laura; Pepper, Joshua; Rodriguez, Joseph E.; Siverd, Robert J.; Stassun, Keivan G.; Kielkopf, John F.

2017-07-01

Using the Spitzer Space Telescope, we observed a transit at 3.6 μm of KELT-11b. We also observed three partial planetary transits from the ground. We simultaneously fit these observations, ground-based photometry from Pepper et al., radial velocity data from Pepper et al., and a spectral energy distribution (SED) model using catalog magnitudes and the Hipparcos parallax to the system. The only significant difference between our results and those of Pepper et al. is that we find the orbital period to be shorter by 37 s, 4.73610 ± 0.00003 versus 4.73653 ± 0.00006 days, and we measure a transit center time of {{BJD}}{TDB} 2457483.4310 ± 0.0007, which is 42 minutes earlier than predicted. Using our new photometry, we precisely measure the density of the star KELT-11 to 4%. By combining the parallax and catalog magnitudes of the system, we are able to measure the radius of KELT-11b essentially empirically. Coupled with the stellar density, this gives a parallactic mass and radius of 1.8 {M}⊙ and 2.9 {R}⊙ , which are each approximately 1σ higher than the adopted model-estimated mass and radius. If we conduct the same fit using the expected parallax uncertainty from the final Gaia data release, this difference increases to 4σ. The differences between the model and parallactic masses and radii for KELT-11 demonstrate the role that precise Gaia parallaxes, coupled with simultaneous photometric, radial velocity, and SED fitting, can play in determining stellar and planetary parameters. With high-precision photometry of transiting planets and high-precision Gaia parallaxes, the parallactic mass and radius uncertainties of stars become 1% and 3%, respectively. TESS is expected to discover 60-80 systems where these measurements will be possible. These parallactic mass and radius measurements have uncertainties small enough that they may provide observational input into the stellar models themselves.

The Intrinsically X-Ray-weak Quasar PHL 1811. II. Optical and UV Spectra and Analysis

NASA Astrophysics Data System (ADS)

Leighly, Karen M.; Halpern, Jules P.; Jenkins, Edward B.; Casebeer, Darrin

2007-11-01

This is the second of two papers reporting observations and analysis of the unusually bright (mb=14.4), luminous (MB=-25.5), nearby (z=0.192) narrow-line quasar PHL 1811. The first paper reported that PHL 1811 is intrinsically X-ray-weak and presented a spectral energy distribution (SED). Here we present HST STIS optical and UV spectra, and ground-based optical spectra. The optical and UV line emission is very unusual. There is no evidence for forbidden or semiforbidden lines. The near-UV spectrum is dominated by very strong Fe II and Fe III, and unusual low-ionization lines such as Na I D and Ca II H and K are observed. High-ionization lines are very weak; C IV has an equivalent width of 6.6 Å, a factor of ~5 smaller than measured from quasar composite spectra. An unusual feature near 1200 Å can be deblended in terms of Lyα, N V, Si II, and C III* using the blueshifted C IV profile as a template. Photoionization modeling shows that the unusual line emission can be explained qualitatively by the unusually soft SED. Principally, a low gas temperature results in inefficient emission of collisionally excited lines, including the semiforbidden lines generally used as density diagnostics. The emission resembles that of high-density gas; in both cases this is a consequence of inefficient cooling. PHL 1811 is very unusual, but we note that quasar surveys may be biased against finding similar objects. Based on observations made with the NASA/ESA Hubble Space Telescope, obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS5-26555. These observations are associated with proposal 9181. Based on observations obtained at Kitt Peak National Observatory, a division of the National Optical Astronomy Observatories, which is operated by the Association of Universities for Research in Astronomy, Inc., under cooperative agreement with the National Science Foundation.
Half of the Most Luminous Quasars May Be Obscured: Investigating the Nature of WISE-Selected Hot Dust-Obscured Galaxies

NASA Astrophysics Data System (ADS)

Assef, R. J.; Eisenhardt, P. R. M.; Stern, D.; Tsai, C.-W.; Wu, J.; Wylezalek, D.; Blain, A. W.; Bridge, C. R.; Donoso, E.; Gonzales, A.; Griffith, R. L.; Jarrett, T. H.

2015-05-01

The Wide-field Infrared Survey Explorer mission has unveiled a rare population of high-redshift (z = 1-4.6), dusty, hyper-luminous galaxies, with infrared luminosities {{L}IR}\\gt {{10}13} {{L}⊙ }, and sometimes exceeding {{10}14} {{L}⊙ }. Previous work has shown that their dust temperatures and overall far-infrared spectral energy distributions (SEDs) are significantly hotter than expected to be powered by star formation. We present here an analysis of the rest-frame optical through mid-infrared SEDs for a large sample of these so-called “hot, dust-obscured galaxies” (Hot DOGs). We find that the SEDs of Hot DOGs are generally well modeled by the combination of a luminous, yet obscured active galactic nuclei (AGNs) that dominates the rest-frame emission at λ \\gt 1 μ m and the bolometric luminosity output, and a less luminous host galaxy that is responsible for the bulk of the rest optical/UV emission. Even though the stellar mass of the host galaxies may be as large as 1011-1012 M⊙, the AGN emission, with a range of luminosities comparable to those of the most luminous QSOs known, require that either Hot DOGs have black hole masses significantly in excess of the local relations, or that they radiate significantly above the Eddington limit, at a level at least 10 times more efficiently than z ˜ 2 QSOs. We show that, while rare, the number density of Hot DOGs is comparable to that of equally luminous but unobscured (i.e., Type 1) QSOs. This may be at odds with the trend suggested at lower luminosities for the fraction of obscured AGNs to decrease with increasing luminosity. That trend may, instead, reverse at higher luminosities. Alternatively, Hot DOGs may not be the torus-obscured counterparts of the known optically selected, largely unobscured, hyper-luminous QSOs, and may represent a new component of the galaxy evolution paradigm. Finally, we discuss the environments of Hot DOGs and statistically show that these objects are in regions as dense as those of known high-redshift proto-clusters.
DETECTION OF STRONG MILLIMETER EMISSION FROM THE CIRCUMSTELLAR DUST DISK AROUND V1094 SCO: COLD AND MASSIVE DISK AROUND A T TAURI STAR IN A QUIESCENT ACCRETION PHASE?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tsukagoshi, Takashi; Kohno, Kotaro; Saito, Masao

2011-01-01

We present the discovery of a cold massive dust disk around the T Tauri star V1094 Sco in the Lupus molecular cloud from the 1.1 mm continuum observations with AzTEC on ASTE. A compact (r{approx}< 320 AU) continuum emission coincides with the stellar position having a flux density of 272 mJy, which is the largest among T Tauri stars in Lupus. We also present the detection of molecular gas associated with the star in the five-point observations in {sup 12}CO J = 3-2 and {sup 13}CO J = 3-2. Since our {sup 12}CO and {sup 13}CO observations did not showmore » any signature of a large-scale outflow or a massive envelope, the compact dust emission is likely to come from a disk around the star. The observed spectral energy distribution (SED) of V1094 Sco shows no distinct turnover from near-infrared to millimeter wavelengths, can be well described by a flattened disk for the dust component, and no clear dip feature around 10 {mu}m suggestive of the absence of an inner hole in the disk. We fit a simple power-law disk model to the observed SED. The estimated disk mass ranges from 0.03 M{sub sun} to {approx}>0.12 M{sub sun}, which is one or two orders of magnitude larger than the median disk mass of T Tauri stars in Taurus. The resultant temperature is lower than that of a flared disk with well-mixed dust in hydrostatic equilibrium and is probably attributed to the flattened disk geometry for the dust which the central star cannot illuminate efficiently. From these results, together with the fact that there is no signature of an inner hole in the SED, we suggest that the dust grains in the disk around V1094 Sco sank into the midplane with grain growth by coalescence and are in the evolutional stage just prior to or at the formation of planetesimals.« less
Broadband study of blazar 1ES 1959+650 during flaring state in 2016

NASA Astrophysics Data System (ADS)

Patel, S. R.; Shukla, A.; Chitnis, V. R.; Dorner, D.; Mannheim, K.; Acharya, B. S.; Nagare, B. J.

2018-03-01

Aims: The nearby TeV blazar 1ES 1959+650 (z = 0.047) was reported to be in flaring state during June-July 2016 by Fermi-LAT, FACT, MAGIC and VERITAS collaborations. We studied the spectral energy distributions (SEDs) in different states of the flare during MJD 57530-57589 using simultaneous multiwaveband data with the aim of understanding the possible broadband emission scenario during the flare. Methods: The UV-optical and X-ray data from UVOT and XRT respectively on board Swift and high energy γ-ray data from Fermi-LAT were used to generate multiwaveband lightcurves as well as to obtain high flux states and quiescent state SEDs. The correlation and lag between different energy bands was quantified using discrete correlation function. The synchrotron self-Compton (SSC) model was used to reproduce the observed SEDs during flaring and quiescent states of the source. Results: A good correlation is seen between X-ray and high energy γ-ray fluxes. The spectral hardening with increase in the flux is seen in X-ray band. The power law index vs. flux plot in γ-ray band indicates the different emission regions for 0.1-3 GeV and 3-300 GeV energy photons. Two zone SSC model satisfactorily fits the observed broadband SEDs. The inner zone is mainly responsible for producing synchrotron peak and high energy γ-ray part of the SED in all states. The second zone is mainly required to produce less variable optical-UV and low energy γ-ray emission. Conclusions: Conventional single zone SSC model does not satisfactorily explain broadband emission during observation period considered. There is an indication of two emission zones in the jet which are responsible for producing broadband emission from optical to high energy γ-rays.
Effects of maternal high-fat diet and sedentary lifestyle on susceptibility of adult offspring to ozone exposure in rats.

PubMed

Gordon, C J; Phillips, P M; Johnstone, A F M; Schmid, J; Schladweiler, M C; Ledbetter, A; Snow, S J; Kodavanti, U P

2017-05-01

Epidemiological and experimental data suggest that obesity exacerbates the health effects of air pollutants such as ozone (O 3 ). Maternal inactivity and calorically rich diets lead to offspring that show signs of obesity. Exacerbated O 3 susceptibility of offspring could thus be manifested by maternal obesity. Thirty-day-old female Long-Evans rats were fed a control (CD) or high-fat (HF) (60% calories) diet for 6 wks and then bred. GD1 rats were then housed with a running wheel (RW) or without a wheel (SED) until parturition, creating four groups of offspring: CD-SED, CD-RW, HF-SED and HF-RW. HF diet was terminated at PND 35 and all offspring were placed on CD. Body weight and %fat of dams were greatest in order; HF-SED > HF-RW > CD-SED > CD-RW. Adult offspring were exposed to O 3 for two consecutive days (0.8 ppm, 4 h/day). Glucose tolerance tests (GTT), ventilatory parameters (plethysmography), and bronchoalveolar fluid (BALF) cell counts and protein biomarkers were performed to assess response to O 3 . Exercise and diet altered body weight and %fat of young offspring. GTT, ventilation and BALF cell counts were exacerbated by O 3 with responses markedly exacerbated in males. HF diet and O 3 led to significant exacerbation of several BALF parameters: total cell count, neutrophils and lymphocytes were increased in male HF-SED versus CD-SED. Males were hyperglycemic after O 3 exposure and exhibited exacerbated GTT responses. Ventilatory dysfunction was also exacerbated in males. Maternal exercise had minimal effects on O 3 response. The results of this exploratory study suggest a link between maternal obesity and susceptibility to O 3 in their adult offspring in a sex-specific manner.
The MUSCLES Treasury Survey. III. X-Ray to Infrared Spectra of 11 M and K Stars Hosting Planets

NASA Astrophysics Data System (ADS)

Loyd, R. O. P.; France, Kevin; Youngblood, Allison; Schneider, Christian; Brown, Alexander; Hu, Renyu; Linsky, Jeffrey; Froning, Cynthia S.; Redfield, Seth; Rugheimer, Sarah; Tian, Feng

2016-06-01

We present a catalog of panchromatic spectral energy distributions (SEDs) for 7 M and 4 K dwarf stars that span X-ray to infrared wavelengths (5 Å -5.5 μm). These SEDs are composites of Chandra or XMM-Newton data from 5-˜50 Å, a plasma emission model from ˜50-100 Å, broadband empirical estimates from 100-1170 Å, Hubble Space Telescope data from 1170-5700 Å, including a reconstruction of stellar Lyα emission at 1215.67 Å, and a PHOENIX model spectrum from 5700-55000 Å. Using these SEDs, we computed the photodissociation rates of several molecules prevalent in planetary atmospheres when exposed to each star’s unattenuated flux (“unshielded” photodissociation rates) and found that rates differ among stars by over an order of magnitude for most molecules. In general, the same spectral regions drive unshielded photodissociations both for the minimally and maximally FUV active stars. However, for O3 visible flux drives dissociation for the M stars whereas near-UV flux drives dissociation for the K stars. We also searched for an far-UV continuum in the assembled SEDs and detected it in 5/11 stars, where it contributes around 10% of the flux in the range spanned by the continuum bands. An ultraviolet continuum shape is resolved for the star ɛ Eri that shows an edge likely attributable to Si II recombination. The 11 SEDs presented in this paper, available online through the Mikulski Archive for Space Telescopes, will be valuable for vetting stellar upper-atmosphere emission models and simulating photochemistry in exoplanet atmospheres.
Diagnostic accuracy of uriSed automated urine microscopic sediment analyzer and dipstick parameters in predicting urine culture test results.

PubMed

Huysal, Kağan; Budak, Yasemin U; Karaca, Ayse Ulusoy; Aydos, Murat; Kahvecioğlu, Serdar; Bulut, Mehtap; Polat, Murat

2013-01-01

Urinary tract infection (UTI) is one of the most common types of infection. Currently, diagnosis is primarily based on microbiologic culture, which is time- and labor-consuming. The aim of this study was to assess the diagnostic accuracy of urinalysis results from UriSed (77 Electronica, Budapest, Hungary), an automated microscopic image-based sediment analyzer, in predicting positive urine cultures. We examined a total of 384 urine specimens from hospitalized patients and outpatients attending our hospital on the same day for urinalysis, dipstick tests and semi-quantitative urine culture. The urinalysis results were compared with those of conventional semiquantitative urine culture. Of 384 urinary specimens, 68 were positive for bacteriuria by culture, and were thus considered true positives. Comparison of these results with those obtained from the UriSed analyzer indicated that the analyzer had a specificity of 91.1%, a sensitivity of 47.0%, a positive predictive value (PPV) of 53.3% (95% confidence interval (CI) = 40.8-65.3), and a negative predictive value (NPV) of 88.8% (95% CI = 85.0-91.8%). The accuracy was 83.3% when the urine leukocyte parameter was used, 76.8% when bacteriuria analysis of urinary sediment was used, and 85.1% when the bacteriuria and leukocyturia parameters were combined. The presence of nitrite was the best indicator of culture positivity (99.3% specificity) but had a negative likelihood ratio of 0.7, indicating that it was not a reliable clinical test. Although the specificity of the UriSed analyzer was within acceptable limits, the sensitivity value was low. Thus, UriSed urinalysis resuIts do not accurately predict the outcome of culture.
The Virtual Observatory Service TheoSSA: Establishing a Database of Synthetic Stellar Flux Standards II. NLTE Spectral Analysis of the OB-Type Subdwarf Feige 110

NASA Technical Reports Server (NTRS)

Rauch, T.; Rudkowski, A.; Kampka, D.; Werner, K.; Kruk, J. W.; Moehler, S.

2014-01-01

Context. In the framework of the Virtual Observatory (VO), the German Astrophysical VO (GAVO) developed the registered service TheoSSA (Theoretical Stellar Spectra Access). It provides easy access to stellar spectral energy distributions (SEDs) and is intended to ingest SEDs calculated by any model-atmosphere code, generally for all effective temperatures, surface gravities, and elemental compositions. We will establish a database of SEDs of flux standards that are easily accessible via TheoSSA's web interface. Aims. The OB-type subdwarf Feige 110 is a standard star for flux calibration. State-of-the-art non-local thermodynamic equilibrium stellar-atmosphere models that consider opacities of species up to trans-iron elements will be used to provide a reliable synthetic spectrum to compare with observations. Methods. In case of Feige 110, we demonstrate that the model reproduces not only its overall continuum shape from the far-ultraviolet (FUV) to the optical wavelength range but also the numerous metal lines exhibited in its FUV spectrum. Results. We present a state-of-the-art spectral analysis of Feige 110. We determined Teff =47 250 +/- 2000 K, log g=6.00 +/- 0.20, and the abundances of He, N, P, S, Ti, V, Cr, Mn, Fe, Co, Ni, Zn, and Ge. Ti, V, Mn, Co, Zn, and Ge were identified for the first time in this star. Upper abundance limits were derived for C, O, Si, Ca, and Sc. Conclusions. The TheoSSA database of theoretical SEDs of stellar flux standards guarantees that the flux calibration of astronomical data and cross-calibration between different instruments can be based on models and SEDs calculated with state-of-the-art model atmosphere codes.
Lifelong exercise, but not short-term high-intensity interval training, increases GDF11, a marker of successful aging: a preliminary investigation.

PubMed

Elliott, Bradley T; Herbert, Peter; Sculthorpe, Nicholas; Grace, Fergal M; Stratton, Daniel; Hayes, Lawrence D

2017-07-01

Lifelong exercise is associated with regulation of skeletal mass and function, reductions in frailty, and successful aging. Yet, the influence of exercise on myostatin and myostatin-interacting factors is relatively under examined in older males. Therefore, we investigated whether serum total myostatin, free myostatin, follistatin, and growth and differentiation factor 11 (GDF11) were altered following high-intensity interval training (HIIT) in a group of 13 lifelong sedentary (SED; 64 [6] years) and 11 lifelong exercising (LEX; 62 [6] years) older males. SED follistatin was moderately greater than LEX pre-HIIT (Cohen's d = 0.66), and was largely greater post-HIIT (Cohen's d = 1.22). The HIIT-induced increase in follistatin was large in SED (Cohen's d = 0.82) and absent in LEX (Cohen's d = 0.03). GDF11 was higher in LEX pre-HIIT (Cohen's d = 0.49) and post-HIIT (Cohen's d = 0.63) compared to SED HIIT resulted in no change to GDF11 in LEX or SED (Cohen's d = 0.00-0.03). Peak power output and GDF11 were correlated ( r = 0.603), independent of grouping. Differences in GDF11 with lifelong exercise training, paired with the correlation between GDF11 and peak power output, suggested that GDF11 may be a relevant myostatin-interacting peptide to successful aging in humans, and strategies to maintain this need to be further explored. © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.
Voluntary wheel running augments aortic l-arginine transport and endothelial function in rats with chronic kidney disease.

PubMed

Martens, Christopher R; Kuczmarski, James M; Kim, Jahyun; Guers, John J; Harris, M Brennan; Lennon-Edwards, Shannon; Edwards, David G

2014-08-15

Reduced nitric oxide (NO) synthesis contributes to risk for cardiovascular disease in chronic kidney disease (CKD). Vascular uptake of the NO precursor l-arginine (ARG) is attenuated in rodents with CKD, resulting in reduced substrate availability for NO synthesis and impaired vascular function. We tested the effect of 4 wk of voluntary wheel running (RUN) and/or ARG supplementation on endothelium-dependent relaxation (EDR) in rats with CKD. Twelve-week-old male Sprague-Dawley rats underwent ⅚ ablation infarction surgery to induce CKD, or SHAM surgery as a control. Beginning 4 wk following surgery, CKD animals either remained sedentary (SED) or received one of the following interventions: supplemental ARG, RUN, or combined RUN+ARG. Animals were euthanized 8 wk after surgery, and EDR was assessed. EDR was significantly impaired in SED vs. SHAM animals after 8 wk, in response to ACh (10(-9)-10(-5) M) as indicated by a reduced area under the curve (AUC; 44.56 ± 9.01 vs 100 ± 4.58, P < 0.05) and reduced maximal response (Emax; 59.9 ± 9.67 vs. 94.31 ± 1.27%, P < 0.05). AUC was not improved by ARG treatment but was significantly improved above SED animals in both RUN and RUN+ARG-treated animals. Maximal relaxation was elevated above SED in RUN+ARG animals only. l-[(3)H]arginine uptake was impaired in both SED and ARG animals and was improved in RUN and RUN+ARG animals. The results suggest that voluntary wheel running is an effective therapy to improve vascular function in CKD and may be more beneficial when combined with l-arginine. Copyright © 2014 the American Physiological Society.
Twenty-four Hours of Sleep, Sedentary Behavior, and Physical Activity with Nine Wearable Devices.

PubMed

Rosenberger, Mary E; Buman, Matthew P; Haskell, William L; McConnell, Michael V; Carstensen, Laura L

2016-03-01

Getting enough sleep, exercising, and limiting sedentary activities can greatly contribute to disease prevention and overall health and longevity. Measuring the full 24-h activity cycle-sleep, sedentary behavior (SED), light-intensity physical activity (LPA), and moderate-to-vigorous physical activity (MVPA)-may now be feasible using small wearable devices. This study compared nine devices for accuracy in a 24-h activity measurement. Adults (n = 40, 47% male) wore nine devices for 24 h: ActiGraph GT3X+, activPAL, Fitbit One, GENEactiv, Jawbone Up, LUMOback, Nike Fuelband, Omron pedometer, and Z-Machine. Comparisons (with standards) were made for total sleep time (Z-machine), time spent in SED (activPAL), LPA (GT3X+), MVPA (GT3X+), and steps (Omron). Analysis included mean absolute percent error, equivalence testing, and Bland-Altman plots. Error rates ranged from 8.1% to 16.9% for sleep, 9.5% to 65.8% for SED, 19.7% to 28.0% for LPA, 51.8% to 92% for MVPA, and 14.1% to 29.9% for steps. Equivalence testing indicated that only two comparisons were significantly equivalent to standards: the LUMOback for SED and the GT3X+ for sleep. Bland-Altman plots indicated GT3X+ had the closest measurement for sleep, LUMOback for SED, GENEactiv for LPA, Fitbit for MVPA, and GT3X+ for steps. Currently, no device accurately captures activity data across the entire 24-h day, but the future of activity measurement should aim for accurate 24-h measurement as a goal. Researchers should continue to select measurement devices on the basis of their primary outcomes of interest.
Dust Attenuation and H(alpha) Star Formation Rates of Z Approx. 0.5 Galaxies

NASA Technical Reports Server (NTRS)

Ly, Chun; Malkan, Matthew A.; Kashikawa, Nobunari; Ota, Kazuaki; Shimasaku, Kazuhiro; Iye, Masanori; Currie, Thayne

2012-01-01

Using deep narrow-band and broad-band imaging, we identify 401 z approximately 0.40 and 249 z approximately 0.49 H-alpha line-emitting galaxies in the Subaru Deep Field. Compared to other H-alpha surveys at similar redshifts, our samples are unique since they probe lower H-alpha luminosities, are augmented with multi-wavelength (rest-frame 1000AA--1.5 microns) coverage, and a large fraction (20%) of our samples has already been spectroscopically confirmed. Our spectra allow us to measure the Balmer decrement for nearly 60 galaxies with H-beta detected above 5-sigma. The Balmer decrements indicate an average extinction of A(H-alpha)=0.7(uparrow){+1.4}_{-0.7} mag. We find that the Balmer decrement systematically increases with higher H-alpha luminosities and with larger stellar masses, in agreement with previous studies with sparser samples. We find that the SFRs estimated from modeling the spectral energy distribution (SED) is reliable---we derived an "intrinsic" H-alpha luminosity which is then reddened assuming the color excess from SED modeling. The SED-predicted H-alpha luminosity agrees with H-alpha narrow-band measurements over 3 dex (rms of 0.25 dex). We then use the SED SFRs to test different statistically-based dust corrections for H-alpha and find that adopting one magnitude of extinction is inappropriate: galaxies with lower luminosities are less reddened. We find that the luminosity-dependent dust correction of Hopkins et al. yields consistent results over 3 dex (rms of 0.3 dex). Our comparisons are only possible by assuming that stellar reddening is roughly half of nebular reddening. The strong correspondence argue that with SED modeling, we can derive reliable intrinsic SFRs even in the absence of H-alpha measurements at z approximately 0.5.
Measuring Range Anxiety: the Substitution-Emergency-Detour (SED) Method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lin, Zhenhong

Range anxiety has been widely recognized as a critical barrier for battery electric vehicles (BEV), but its measurement method is lacking. Such a knowledge gap makes it difficult to analyse the competiveness of and the demand for BEVs. This study develops the Substitution-Emergency-Detour (SED) method to measure the range anxiety cost, and conducts sensitivity analysis of range anxiety cost with respect to nine factors. It is found that the most effective ways to reduce range anxiety are reducing driving intensity, increasing the vehicle range, extending the vehicle range with better charging infrastructure. Better household vehicle flexibility and less range uncertaintymore » can also significantly reduce range anxiety. The SED method and the numerical results are expected to contribute to better understanding of the range anxiety barrier and the BEV demand.« less
Radar cross-section measurements and simulation of a tethered satellite. The small expendable deployer system end-mass payload

NASA Technical Reports Server (NTRS)

Cravey, Robin L.; Fralick, Dion T.; Vedeler, Erik

1995-01-01

The first Small Expendable Deployer System (SEDS-1), a tethered satellite system, was developed by NASA and launched March 29, 1993 as a secondary payload on a United State Air Force (USAF) Delta-2 launch vehicle. The SEDS-1 successfully deployed an instrumented end-mass payload (EMP) on a 20-km nonconducting tether from the second stage of the Delta 2. This paper describes the effort of NASA Langley Research Center's Antenna and Microwave Research Branch to provide assistance to the SEDS Investigators Working Group (IWG) in determining EMP dynamics by analyzing the mission radar skin track data. The radar cross section measurements taken and simulations done for this study are described and comparisons of the measured data with the simulated data for the EMP at 6 GHz are presented.
Modeling X-ray and gamma-ray emission in the intrabinary shock of pulsar binaries

NASA Astrophysics Data System (ADS)

An, H.

2017-10-01

We present broadband SED and light curve, and a wind interaction model for the gamma-ray binary 1FGL J1018.6-5856 (J1018) which exhibits double peaks in the X-ray light curve. Assuming that the X-ray to low-energy gamma-ray emission is produced by synchrotron radiation and high-energy gamma rays by inverse Compton scattering in the intrabinary shock (IBS), we model the broadband SED and light curve of J1018 using a two-component model having slow electrons in the shock and fast bulk-accelerated electrons at the skin of the shock. The model explains the broadband SED and light curve of J1018 qualitatively well. In particular, modeling the synchrotron emission constrains the orbital geometry. We discuss potential use of the model for other pulsar binaries.
Poverty and the Growth of Emotional and Conduct Problems in Children with Autism With and Without Comorbid ADHD.

PubMed

Flouri, Eirini; Midouhas, Emily; Charman, Tony; Sarmadi, Zahra

2015-09-01

We investigated the longitudinal relationship between socio-economic disadvantage (SED) and trajectories of emotional and conduct problems among children with autism spectrum disorder (ASD) who had comorbid attention deficit/hyperactivity disorder (ADHD; ASD + ADHD) or not (ASD - ADHD). The sample was 209 children with ASD who took part in the UK's Millennium Cohort Study. Trajectories of problems across ages 3, 5 and 7 years were analyzed using growth curve models. The ASD - ADHD group decreased in conduct problems over time but the ASD + ADHD group continued on a high trajectory. Although SED was not a risk factor for ASD + ADHD, it was associated with elevated emotional problems among children with ASD + ADHD. This effect of SED on emotional problems was not attenuated by parenting or peer problems.
Learning the Relationship between Galaxy Spectra and Star Formation Histories

NASA Astrophysics Data System (ADS)

Lovell, Christopher; Acquaviva, Viviana; Iyer, Kartheik; Gawiser, Eric

2018-01-01

We explore novel approaches to the problem of predicting a galaxy’s star formation history (SFH) from its Spectral Energy Distribution (SED). Traditional approaches to SED template fitting use constant or exponentially declining SFHs, and are known to incur significant bias in the inferred SFHs, which are typically skewed toward younger stellar populations. Machine learning approaches, including tree ensemble methods and convolutional neural networks, would not be affected by the same bias, and may work well in recovering unbiased and multi-episodic star formation histories. We use a supervised approach whereby models are trained using synthetic spectra, generated from three state of the art hydrodynamical simulations, including nebular emission. We explore how SED feature maps can be used to highlight areas of the spectrum with the highest predictive power and discuss the limitations of the approach when applied to real data.
High Risk for Severe Emotional Dysregulation in Psychiatrically Referred Youth with Autism Spectrum Disorder: A Controlled Study.

PubMed

Joshi, Gagan; Wozniak, Janet; Fitzgerald, Maura; Faraone, Stephen; Fried, Ronna; Galdo, Maribel; Furtak, Stephannie L; Conroy, Kristina; Kilcullen, J Ryan; Belser, Abigail; Biederman, Joseph

2018-04-19

To assess prevalence and severity of emotional dysregulation (ED) in psychiatrically referred youth with autism spectrum disorder (ASD). ASD youth (N = 123) were compared to youth with attention-deficit/hyperactivity disorder (ADHD) and controls. The majority of psychiatrically referred youth with ASD had positive Child Behavior Checklist-ED (CBCL-ED) profile that was significantly higher than in youth with ADHD (82 vs. 53%; p < 0.001). The severe emotional dysregulation (SED) profile was significantly greater in ASD youth than ADHD (44 vs. 15%; p < 0.001). In the presence of SED profile ASD youth suffered from greater severity of autism, associated psychopathology, and psychosocial dysfunction. Greater than expected prevalence of SED in psychiatrically referred youth with ASD that identifies distinct clinical correlates associated with severe morbidity and dysfunction.
Planck intermediate results: XXIX. All-sky dust modelling with Planck, IRAS, and WISE observations

DOE PAGES

Ade, P. A. R.; Aghanim, N.; Alves, M. I. R.; ...

2016-02-09

In this paper, we present all-sky modelling of the high resolution Planck, IRAS, and WISE infrared (IR) observations using the physical dust model presented by Draine & Li in 2007 (DL, ApJ, 657, 810). We study the performance and results of this model, and discuss implications for future dust modelling. The present work extends the DL dust modelling carried out on nearby galaxies using Herschel and Spitzer data to Galactic dust emission. We employ the DL dust model to generate maps of the dust mass surface density Σ Md, the dust optical extinction A V, and the starlight intensity heatingmore » the bulk of the dust, parametrized by U min. The DL model reproduces the observed spectral energy distribution (SED) satisfactorily over most of the sky, with small deviations in the inner Galactic disk and in low ecliptic latitude areas, presumably due to zodiacal light contamination. In the Andromeda galaxy (M31), the present dust mass estimates agree remarkably well (within 10%) with DL estimates based on independent Spitzer and Herschel data. We compare the DL optical extinction A V for the diffuse interstellar medium (ISM) with optical estimates for approximately 2 × 10 5 quasi-stellar objects (QSOs) observed inthe Sloan Digital Sky Survey (SDSS). The DL A V estimates are larger than those determined towards QSOs by a factor of about 2, which depends on U min. The DL fitting parameter U min, effectively determined by the wavelength where the SED peaks, appears to trace variations in the far-IR opacity of the dust grains per unit A V, and not only in the starlight intensity. These results show that some of the physical assumptions of the DL model will need to be revised. To circumvent the model deficiency, we propose an empirical renormalization of the DL A V estimate, dependent of U min, which compensates for the systematic differences found with QSO observations. This renormalization, made to match the A V estimates towards QSOs, also brings into agreement the DL A V estimates with those derived for molecular clouds from the near-IR colours of stars in the 2 micron all sky survey (2MASS). The DL model and the QSOs data are also used to compress the spectral information in the Planck and IRAS observations for the diffuse ISM to a family of 20 SEDs normalized per A V, parameterized by U min, which may be used to test and empirically calibrate dust models. Finally, the family of SEDs and the maps generated with the DL model are made public in the Planck Legacy Archive.« less
Dust spectral energy distributions of nearby galaxies: an insight from the Herschel Reference Survey

NASA Astrophysics Data System (ADS)

Ciesla, L.; Boquien, M.; Boselli, A.; Buat, V.; Cortese, L.; Bendo, G. J.; Heinis, S.; Galametz, M.; Eales, S.; Smith, M. W. L.; Baes, M.; Bianchi, S.; De Looze, I.; di Serego Alighieri, S.; Galliano, F.; Hughes, T. M.; Madden, S. C.; Pierini, D.; Rémy-Ruyer, A.; Spinoglio, L.; Vaccari, M.; Viaene, S.; Vlahakis, C.

2014-05-01

Although it accounts only for a small fraction of the baryonic mass, dust has a profound impact on the physical processes at play in galaxies. Thus, to understand the evolution of galaxies, it is essential not only to characterize dust properties per se, but also in relation to global galaxy properties. To do so, we derive the dust properties of galaxies in a volume limited, K-band selected sample, the Herschel Reference Survey (HRS). We gather infrared photometric data from 8 μm to 500 μm from Spitzer, WISE, IRAS, and Herschel for all of the HRS galaxies. Draine & Li (2007, ApJ, 663, 866) models are fit to the data from which the stellar contribution has been carefully removed. We find that our photometric coverage is sufficient to constrain all of the parameters of the Draine & Li models and that a strong constraint on the 20-60 μm range is mandatory to estimate the relative contribution of the photo-dissociation regions to the infrared spectral energy distribution (SED). The SED models tend to systematically underestimate the observed 500 μm flux densities, especially for low-mass systems. We provide the output parameters for all of the galaxies, i.e., the minimum intensity of the interstellar radiation field, the fraction of polycyclic aromatic hydrocarbon (PAH), the relative contribution of PDR and evolved stellar population to the dust heating, the dust mass, and the infrared luminosity. For a subsample of gas-rich galaxies, we analyze the relations between these parameters and the main integrated properties of galaxies, such as stellar mass, star formation rate, infraredluminosity, metallicity, Hα and H-band surface brightness, and the far-ultraviolet attenuation. A good correlation between the fraction of PAH and the metallicity is found, implying a weakening of the PAH emission in galaxies with low metallicities and, thus, low stellar masses. The intensity of the diffuse interstellar radiation field and the H-band and Hα surface brightnesses are correlated, suggesting that the diffuse dust component is heated by both the young stars in star-forming regions and the diffuse evolved population. We use these results to provide a new set of infrared templates calibrated with Herschel observations on nearby galaxies and a mean SED template to provide the z = 0 reference for cosmological studies. For the same purpose, we place our sample on the SFR - M∗ diagram. The templates are compared to the most popular infrared SED libraries, enlightening a large discrepancy between all of them in the 20-100 μm range. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.Table 4 and appendices are available in electronic form at http://www.aanda.org

State Energy Data System

EIA Publications

2017-01-01

The State Energy Data System (SEDS) is the U.S. Energy Information Administration's (EIA) source for comprehensive state energy statistics. Included are estimates of energy production, consumption, prices, and expenditures broken down by energy source and sector. Production and consumption estimates begin with the year 1960 while price and expenditure estimates begin with 1970. The multidimensional completeness of SEDS allows users to make comparisons across states, energy sources, sectors, and over time.
Reconstructing The Star Formation Histories Of Galaxies Through Sed Fitting Using The Dense Basis Method

NASA Astrophysics Data System (ADS)

Iyer, Kartheik; Gawiser, Eric

2017-06-01

The Dense Basis SED fitting method reveals previously inaccessible information about the number and duration of star formation episodes and the timing of stellar mass assembly as well as uncertainties in these quantities, in addition to accurately recovering traditional SED parameters including M*, SFR and dust attenuation. This is done using basis Star Formation Histories (SFHs) chosen by comparing the goodness-of-fit of mock galaxy SEDs to the goodness-of-reconstruction of their SFHs, trained and validated using three independent datasets of mock galaxies at z=1 from SAMs, Hydrodynamic simulations and stochastic realizations. Of the six parametrizations of SFHs considered, we reject the traditional parametrizations of constant and exponential SFHs and suggest four novel improvements, quantifying the bias and scatter of each parametrization. We then apply the method to a sample of 1100 CANDELS GOODS-S galaxies at 110^9 M_sun, in contrast to current simulations. About 40% of the CANDEL galaxies have SFHs whose maximum occurs at or near the epoch of observation. These results are presented in Iyer and Gawiser (2017, ApJ 838 127), available at https://arxiv.org/abs/1702.04371
SN 1986J VLBI. IV. The Nature of the Central Component

NASA Astrophysics Data System (ADS)

Bietenholz, Michael F.; Bartel, Norbert

2017-12-01

We report on Very Large Array measurements between 1 and 45 GHz of the evolving radio spectral energy distribution (SED) of SN 1986J, made in conjunction with very long baseline interferometry (VLBI) imaging. The SED of SN 1986J is unique among supernovae, and shows an inversion point and a high-frequency turnover. Both are due to the central component seen in the VLBI images, and both are progressing downward in frequency with time. The optically thin spectral index of the central component is almost the same as that of the shell. We fit a simple model to the evolving SED consisting of an optically thin shell and a partly absorbed central component. The evolution of the SED is consistent with that of a homologously expanding system. Both components are fading, but the shell is fading more rapidly. We conclude that the central component is physically inside the expanding shell, and not a surface hotspot central only in projection. Our observations are consistent with the central component being due to interaction of the shock with the dense and highly structured circumstellar medium that resulted from a period of common-envelope evolution of the progenitor. However, a young pulsar-wind nebula or emission from an accreting black hole can also not be ruled out at this point.
Modeling the HD 32297 Debris Disk With Far-Infrared Herschel Data

NASA Technical Reports Server (NTRS)

Donaldson, J.K.; Lebreton, J.; Roberge, A.; Augereau, J.-C.; Krivov, A. V.

2013-01-01

HD 32297 is a young A-star (approx. 30 Myr) 112 pc away with a bright edge-on debris disk that has been resolved in scattered light. We observed the HD 32297 debris disk in the far-infrared and sub-millimeter with the Herschel Space Observatory PACS and SPIRE instruments, populating the spectral energy distribution (SED) from 63 to 500 micron..We aimed to determine the composition of dust grains in the HD 32297 disk through SED modeling, using geometrical constraints from the resolved imaging to break the degeneracies inherent in SED modeling. We found the best fitting SED model has two components: an outer ring centered around 110 AU, seen in the scattered light images, and an inner disk near the habitable zone of the star. The outer disk appears to be composed of grains>2 micron consisting of silicates, carbonaceous material, and water ice with an abundance ratio of 1:2:3 respectively and 90% porosity. These grains appear consistent with cometary grains, implying the underlying planetesimal population is dominated by comet-like bodies. We also discuss the 3.7 sigma detection of [C ii] emission at 158 micron with the Herschel PACS instrument, making HD 32297 one of only a handful of debris disks with circumstellar gas detected
DOE Office of Scientific and Technical Information (OSTI.GOV)

Mao, Peiyuan; Urry, C. Megan

We investigate a sample of 622 blazars with measured fluxes at 12 wavebands across the radio-to-gamma-ray spectrum but without spectroscopic or photometric redshifts. This sample includes hundreds of sources with newly analyzed X-ray spectra reported here. From the synchrotron peak frequencies, estimated by fitting the broadband spectral energy distributions (SEDs), we find that the fraction of high-synchrotron-peaked blazars in these 622 sources is roughly the same as in larger samples of blazars that do have redshifts. We characterize the no-redshift blazars using their infrared colors, which lie in the distinct locus called the WISE blazar strip, then estimate their redshiftsmore » using a KNN regression based on the redshifts of the closest blazars in the WISE color–color plot. Finally, using randomly drawn values from plausible redshift distributions, we simulate the SEDs of these blazars and compare them to known blazar SEDs. Based on all these considerations, we conclude that blazars without redshift estimates are unlikely to be high-luminosity, high-synchrotron-peaked objects, which had been suggested in order to explain the “blazar sequence”—an observed trend of SED shape with luminosity—as a selection effect. Instead, the observed properties of no-redshift blazars are compatible with a causal connection between jet power and electron cooling, i.e., a true blazar sequence.« less
The Infrared-Radio Correlation of Dusty Star Forming Galaxies at High Redshift

NASA Astrophysics Data System (ADS)

Lower, Sidney; Vieira, Joaquin Daniel; Jarugula, Sreevani

2018-01-01

Far-infrared (FIR) and radio continuum emission in galaxies are related by a common origin: massive stars and the processes triggered during their birth, lifetime, and death. FIR emission is produced by cool dust, heated by the absorption of UV emission from massive stars, which is then re-emitted in the FIR. Thermal free-free radiation emitted from HII regions dominates the spectral energy density (SED) of galaxies at roughly 30 GHz, while non-thermal synchrotron radiation dominates at lower frequencies. At low redshift, the infrared radio correlation (IRC, or qIR) holds as a tight empirical relation for many star forming galaxy types, but until recently, there has not been sensitive enough radio observations to extend this relation to higher redshifts. Many selection biases cloud the results of these analyses, leaving the evolution of the IRC with redshift ambiguous. In this poster, I present CIGALE fitted spectral energy distributions (SEDs) for 24 gravitationally-lensed sources selected in the mm-wave from the South Pole Telescope (SPT) survey. I fit the IRC from infrared and submillimeter fluxes obtained with Herschel, Atacama Pathfinder Experiment (APEX), and SPT and radio fluxes obtained with ATCA at 2.1, 5.5, 9, and 30 GHz. This sample of SPT sources has a spectroscopic redshift range of 2.1
Effects of torsion on the thermal conductivity of multi-layer graphene

NASA Astrophysics Data System (ADS)

Si, Chao; Lu, Gui; Cao, Bing-Yang; Wang, Xiao-Dong; Fan, Zhen; Feng, Zhi-Hai

2017-05-01

This work employs the equilibrium molecular dynamics method to study the effects of torsion on the thermal conductivity of multi-layer graphene. Thermal conductivities of twisted 10-layer 433.91 × 99.68 Å2 graphene with torsion angles of 0°, 11.25°, 22.5°, 33.75°, 45°, 67.5°, 90°, 112.5°, and 135° are calculated. The corresponding radial distribution functions and nearest atomic distances are calculated to reveal the effects of torsion on lattice structures. The spectral energy density (SED) method is utilized to analyze the phonon transport properties. It is very interesting that the thermal conductivity of multi-layer graphene decreases slightly at first and then increases with the increasing torsion angle, and the valley is located at θG = 22.5° with the lowest thermal conductivity of 4692.40 W m-1 K-1. The torsion effect can be considered as a combination of the compression effect and the dislocation effect. Further SED analysis confirms that the effect of dislocation on thermal conductivities can be negligible, while the compression effect decreases the phonon lifetimes of flexural out-of-plane acoustic (ZA) branches and increases the ZA group velocities and the phonon specific heat. The decrease becomes dominated when the torsion angle is small, whereas the increase becomes more and more dominated when the torsion angle becomes larger, which are responsible for the reported variation of thermal conductivities.
Transition disks: four candidates for ongoing giant planet formation in Ophiuchus

NASA Astrophysics Data System (ADS)

Orellana, M.; Cieza, L. A.; Schreiber, M. R.; Merín, B.; Brown, J. M.; Pellizza, L. J.; Romero, G. A.

2012-03-01

Among the large set of Spitzer-selected transitional disks that we have examined in the Ophiuchus molecular, four disks have been identified as (giant) planet-forming candidates based on the morphology of their spectral energy distributions (SEDs), their apparent lack of stellar companions, and evidence of accretion. Here we characterize the structures of these disks modeling their optical, infrared, and (sub)millimeter SEDs. We use the Monte Carlo radiative transfer package RADMC to construct a parametric model of the dust distribution in a flared disk with an inner cavity and calculate the temperature structure that is consistent with the density profile, when the disk is in thermal equilibrium with the irradiating star. For each object, we conducted a Bayesian exploration of the parameter space generating Monte Carlo Markov chains (MCMC) that allow the identification of the best-fit model parameters and to constrain their range of statistical confidence. Our calculations imply that evacuated cavities with radii ~2-8 AU are present that appear to have been carved by embedded giant planets. We found parameter values that are consistent with those previously given in the literature, indicating that there has been a mild degree of grain growth and dust settling, which deserves to be investigated with further modeling and follow-up observations. Resolved images with (sub)millimeter interferometers would be required to break some of the degeneracies of the models and more tightly constrain the physical properties of these fascinating disks.
METAPHOR: Probability density estimation for machine learning based photometric redshifts

NASA Astrophysics Data System (ADS)

Amaro, V.; Cavuoti, S.; Brescia, M.; Vellucci, C.; Tortora, C.; Longo, G.

2017-06-01

We present METAPHOR (Machine-learning Estimation Tool for Accurate PHOtometric Redshifts), a method able to provide a reliable PDF for photometric galaxy redshifts estimated through empirical techniques. METAPHOR is a modular workflow, mainly based on the MLPQNA neural network as internal engine to derive photometric galaxy redshifts, but giving the possibility to easily replace MLPQNA with any other method to predict photo-z's and their PDF. We present here the results about a validation test of the workflow on the galaxies from SDSS-DR9, showing also the universality of the method by replacing MLPQNA with KNN and Random Forest models. The validation test include also a comparison with the PDF's derived from a traditional SED template fitting method (Le Phare).
A case study of Ionospheric storm effects during long-lasting southward IMF Bz driven geomagnetic storm

NASA Astrophysics Data System (ADS)

Liu, J., Sr.

2014-12-01

Multiple instrumental observations including GPS TEC, foF2 and hmF2 from ionosondes, vertical ion drift measurements from C/NOFS, magnetometer data and far-ultraviolet airglow measured by TIMED/GUVI are used to investigate the profound ionospheric disturbances at mid- and low-latitudes during the 14-17 July 2012 geomagnetic storm event, which was featured by prolonged southward interplanetary geomagnetic field component for about 30 hours below -10 nT. In the East Asian/Australian sector, latitudinal profile of TEC variations in the main phase were characterized by three bands of increments and separated by weak depressions in the Equatorial Ionospheric Anomaly (EIA) crest regions, which were caused by the combined effects of disturbance dynamo electric fields (DDEF) and equatorward neutral winds. In the recovery phase, strong inhibition of EIA occurred and the summer crest of EIA disappeared on 16 July due to the combined effects of intrusion of neutral composition disturbance zone as shown by the TIME/GUVI O/N2 measurements and long-lasting daytime westward DDEF inferred from the equatorial electric electrojet (EEJ) observations. The transit time of DDEF over the dip equator from westward to eastward is around 2200 LT. In the American longitude, the salient ionospheric disturbances in the summer hemisphere were characterized by daytime periodical intrusion of negative phase for three consecutive days in the recovery phase, preceded by storm enhanced density (SED) plume in the initial phase. In addition, multiple short-lived prompt penetration electric fields (PPEF) appeared during stable southward IMF Bz in the recovery phase and were responsible for enhanced the EIA and equatorial ionospheric uplift around sunset.
Small Explorer Data System MIL-STD-1773 fiber optic bus

NASA Technical Reports Server (NTRS)

Flanegan, Mark; Label, Ken

1992-01-01

The MIL-STD-1773 Fiber Optic Data Bus as implemented in the GSFC Small Explorer Data System (SEDS) for the Small Explorer Program is described. It provides an overview of the SEDS MIL-STD-1773 bus components system design considerations, reliability figures, acceptance and qualification testing requirements, radiation requirements and tests, error handling considerations, and component heritage. The first mission using the bus will be launched in June of 1992.
East Europe Report

DTIC Science & Technology

1986-10-22

Nonetheless, the grain harvest was very good. In the fields of the fertile Magdeburg "Boerde," the best that the GDR has, one nationally-owned...Central Committee of the Socialist Unity Party of Germany to the 11th Party Congress of the SED," reporter: E. Honecker, Dietz Publishing Company, East...Committee of the Socialist Unity Party of Germany to the 11th Party Congress of the SED, op. cit., p 24) Representatives of more moderate
White Dwarf Model Atmospheres: Synthetic Spectra for Supersoft Sources

NASA Astrophysics Data System (ADS)

Rauch, Thomas

2013-01-01

The Tübingen NLTE Model-Atmosphere Package (TMAP) calculates fully metal-line blanketed white dwarf model atmospheres and spectral energy distributions (SEDs) at a high level of sophistication. Such SEDs are easily accessible via the German Astrophysical Virtual Observatory (GAVO) service TheoSSA. We discuss applications of TMAP models to (pre) white dwarfs during the hottest stages of their stellar evolution, e.g. in the parameter range of novae and supersoft sources.
Community Mental Health Providers' Beliefs About Addressing Weight Loss Among Youth Clients with Serious Emotional Disturbance and Overweight/Obesity: An Elicitation Study.

PubMed

Wykes, Thomas L; Bourassa, Katelynn A; Slosser, Andrea E; McKibbin, Christine L

2018-02-09

Youth with Serious Emotional Disturbance (SED) have high rates of overweight/obesity. Factors influencing mental health provider intentions to deliver weight-related advice are unclear. This study used qualitative methodology and Theory of Planned Behavior (TPB) constructs to examine these factors. Community mental health providers serving youth with SED were recruited via convenience sampling and an online provider list. Participants completed an open-ended TPB-based questionnaire online. Content analysis identified thematic beliefs. Twenty-one providers completed the questionnaire. Providers identified behavioral beliefs (e.g., client defensiveness), normative beliefs (e.g., medical professionals), and control beliefs (e.g., limited resources) that impact decisions to provide weight-related advice. Knowledge of factors that may influence providers' delivery of weight-related advice may lead to more effective healthy lifestyle programming for youth with SED.
Be Stars in the Open Cluster NGC 6830

NASA Astrophysics Data System (ADS)

Yu, Po-Chieh; Lin, Chien-Cheng; Lin, Hsing-Wen; Lee, Chien-De; Konidaris, Nick; Ngeow, Chow-Choong; Ip, Wing-Huen; Chen, Wen-Ping; Chen, Hui-Chen; Malkan, Matthew A.; Chang, Chan-Kao; Laher, Russ; Huang, Li-Ching; Cheng, Yu-Chi; Edelson, Rick; Ritter, Andreas; Quimby, Robert; Ben-Ami, Sagi; Ofek, Eran. O.; Surace, Jason; Kulkarni, Shrinivas R.

2016-05-01

We report the discovery of two new Be stars, and re-identify one known Be star in the open cluster NGC 6830. Eleven Hα emitters were discovered using the Hα imaging photometry of the Palomar Transient Factory Survey. Stellar membership of the candidates was verified with photometric and kinematic information using 2MASS data and proper motions. The spectroscopic confirmation was carried out by using the Shane 3 m telescope at the Lick observatory. Based on their spectral types, three Hα emitters were confirmed as Be stars with Hα equivalent widths greater than -10 Å. Two objects were also observed by the new spectrograph spectral energy distribution-machine (SED-machine) on the Palomar 60-inch Telescope. The SED-machine results show strong Hα emission lines, which are consistent with the results of the Lick observations. The high efficiency of the SED-machine can provide rapid observations for Be stars in a comprehensive survey in the future.
Star formation history of the galaxy merger Mrk848 with SDSS-IV MaNGA

NASA Astrophysics Data System (ADS)

Yuan, Fang-Ting; Shen, Shiyin; Hao, Lei; Fernandez, Maria Argudo

2017-03-01

With the 3D data of SDSS-IV MaNGA (Bundy et al. 2015) spectra and multi-wavelength SED modeling, we expect to have a better understanding of the distribution of dust, gas and star formation of galaxy mergers. For a case study of the merging galaxy Mrk848, we use both UV-to-IR broadband SED and the MaNGA integral field spectroscopy to obtain its star formation histories at the tail and core regions. From the SED fitting and full spectral fitting, we find that the star formation in the tail regions are affected by the interaction earlier than the core regions. The core regions show apparently two times of star formation and a strong burst within 500Myr, indicating the recent star formation is triggered by the interaction. The star formation histories derived from these two methods are basically consistent.
A dust spectral energy distribution model with hierarchical Bayesian inference - I. Formalism and benchmarking

NASA Astrophysics Data System (ADS)

Galliano, Frédéric

2018-05-01

This article presents a new dust spectral energy distribution (SED) model, named HerBIE, aimed at eliminating the noise-induced correlations and large scatter obtained when performing least-squares fits. The originality of this code is to apply the hierarchical Bayesian approach to full dust models, including realistic optical properties, stochastic heating, and the mixing of physical conditions in the observed regions. We test the performances of our model by applying it to synthetic observations. We explore the impact on the recovered parameters of several effects: signal-to-noise ratio, SED shape, sample size, the presence of intrinsic correlations, the wavelength coverage, and the use of different SED model components. We show that this method is very efficient: the recovered parameters are consistently distributed around their true values. We do not find any clear bias, even for the most degenerate parameters, or with extreme signal-to-noise ratios.
Prevalence of serum IgE antibodies to the Staphylococcus aureus enterotoxins (SAE, SEB, SEC, SED, TSST-1) in patients with persistent allergic rhinitis.

PubMed

Rossi, Renato Enzo; Monasterolo, Giorgio

2004-03-01

Enterotoxins produced by Staphylococcus aureus and their specific IgE antibodies were thought to be important in worsening atopic dermatitis. However, few studies have documented an association between S. aureus or its exotoxins and exacerbations of upper airway/nasal disease. In the current study, we determined the prevalence of serum-specific IgE towards staphylococcal enterotoxin A, B, C, D (SEA, SEB, SEC, SED) and toxic shock syndrome toxin 1 (TSST-1) in patients suffering from rhinitis and/or asthma due to allergy. Therefore, we examined whether SEA, SEB, SEC, SED and TSST-1 were important in worsening the clinical status of patients allergic to house dust mites by means of assessing serum eosinophil cationic protein (ECP), which is thought to be a reliable marker of asthma and rhinitis severity. 198 patients with persistent allergic rhinitis and/or asthma due to house dust mites were evaluated. Specific IgE towards SEA, SEB, SEC, SED, TSST-1, timothy grass and birch pollen recombinant allergens, and other aeroallergen extracts from common allergen sources were evaluated by the Pharmacia CAP System. Serum ECP was assessed, too. The percentages of sensitization to staphylococcal enterotoxins of 198 house dust mite-allergic patients were as follows: TSST-1-specific IgE 24.7% (n=49), SEC-specific IgE 22.2% (n=44), SEB-specific IgE 15.1% (n=30), SEA-specific IgE 9.1% (n=18), and SED-specific IgE 5.5% (n=11). Out of 198 individuals allergic to house dust mites 136 patients suffering from persistent rhinitis were subdivided into two subgroups: 53 patients with serum-specific IgE to at least one staphylococcal enterotoxin and 83 patients without specific IgE towards staphylococcal enterotoxins. Patients sensitive to staphylococcal enterotoxins had higher serum ECP levels than patients lacking specific IgE to SEA, SEB, SEC, SED and TSST-1(geometric mean 24.3 vs. 16.6 microg/100 ml; p=0.029), as well as total IgE levels (geometric mean 564 vs. 161 kU/l, p=0.00063) and specific IgE to Dermatophagoides pteronyssinus (geometric mean 16.7 vs. 6.6 kU/l; p=0.0235) and Dermatophagoides farinae (geometric mean 18.6 vs. 7.8 kU/l; p=0.0246). A status of sensitization to staphylococcal enterotoxins seems to be a factor increasing serum ECP, which is thought to be a reliable marker of clinical severity of allergic disease. Therefore, the evaluation of SEA, SEB, SEC, SED and TSST-1-specific IgE antibodies may have additional significance for the prognosis of persistent allergic diseases of the upper airway. Copyright 2004 S. Karger AG, Basel
StarCAT: A Catalog of Space Telescope Imaging Spectrograph Ultraviolet Echelle Spectra of Stars

NASA Astrophysics Data System (ADS)

Ayres, Thomas R.

2010-03-01

StarCAT is a catalog of high resolution ultraviolet spectra of objects classified as "stars," recorded by Space Telescope Imaging Spectrograph (STIS) during its initial seven years of operations (1997-2004). StarCAT is based on 3184 echelle observations of 545 distinct targets, with a total exposure duration of 5.2 Ms. For many of the objects, broad ultraviolet coverage has been achieved by splicing echellegrams taken in two or more FUV (1150-1700 Å) and/or NUV (1600-3100 Å) settings. In cases of multiple pointings on conspicuously variable sources, spectra were separated into independent epochs. Otherwise, different epochs were combined to enhance the signal-to-noise ratio (S/N). A post-facto correction to the calstis pipeline data sets compensated for subtle wavelength distortions identified in a previous study of the STIS calibration lamps. An internal "fluxing" procedure yielded coherent spectral energy distributions (SEDs) for objects with broadly overlapping wavelength coverage. The best StarCAT material achieves 300 m s-1 internal velocity precision; absolute accuracy at the 1 km s-1 level; photometric accuracy of order 4%; and relative flux precision several times better (limited mainly by knowledge of SEDs of UV standard stars). While StarCAT represents a milestone in the large-scale post-processing of STIS echellegrams, a number of potential improvements in the underlying "final" pipeline are identified.
CAREGIVER'S DEPRESSIVE SYMPTOMS AND YOUNG CHILDREN'S SOCIOEMOTIONAL DEVELOPMENT DELAYS: A CROSS-SECTIONAL STUDY IN POOR RURAL AREAS OF CHINA.

PubMed

Wei, Qianwei; Zhang, Cuihong; Zhang, Jingxu; Luo, Shusheng; Wang, Xiaoli

2018-03-01

Poverty and its associated factors put people at risk for depression. The aims of this study were to describe the prevalence of depressive symptoms (DS) of primary caregivers and socioemotional development (SED) delays of young children in poor rural areas of China, and to explore the association between them. Cross-sectional data of 2,664 children aged 3 to 35 months and their primary caregivers were used for analysis. Characteristics of the child, caregiver, and family were collected through face-to-face caregiver interviews. DS were assessed by the Zung Self-Rating Depression Scale (W.W. Zung, 1965, as cited in World Health Organization, ), and SED was evaluated by the Ages and Stage Questionnaires: Social-Emotional (J. Squires, D. Bricker, & L. Potter, 1997). The χ 2 test, stratification analysis, and logistic regression analyses were used to explore the association. Among the caregivers, 40.3% (95% confidence interval [CI] [38.4, 42.1]), reported DS. Caregivers who were male, older and ethnic minorities as well as had a low level of education, a low family income, or more children were more likely to have DS. Of the children, 24.4% (95% CI [22.8, 26.0]) were recognized with SED delays. Older children displayed more delays than did younger children, but no significant differences between males and females were found. SED delays were significantly associated with mother outmigrating, male caregivers, older age, ethnic minorities, and low education or families with a single parent, low-income, and having more children. Caregivers having DS, odds ratio (OR) = 2.40, 95% CI [1.99, 2.88], was a significant predictor of increased odds of SED delays; other factors were single-parent family, OR = 1.99, 95% CI [1.37, 2.89], inadequate care, OR = 1.69, 95% CI [1.30, 2.21], physical punishment, OR = 1.61, 95% CI [1.33, 1.95], ethnic minorities, OR = 1.41, 95% CI [1.17, 1.71], and child age in months, OR = 1.03, 95% CI [1.02, 1.04], according to the logistic regression analysis. DS are prevalent among caregivers with young children in poor rural areas. Interventions to improve the mental health of caregivers and their parenting behaviors are needed to improve children's SED. © 2018 Michigan Association for Infant Mental Health.

Fluctuations of the intergalactic ionization field at redshift z ~ 2

NASA Astrophysics Data System (ADS)

Agafonova, I. I.; Levshakov, S. A.; Reimers, D.; Hagen, H.-J.; Tytler, D.

2013-04-01

Aims: To probe the spectral energy distribution (SED) of the ionizing background radiation at z ≲ 2 and to specify the sources contributing to the intergalactic radiation field. Methods: The spectrum of a bright quasar HS 1103+6416 (zem = 2.19) contains five successive metal-line absorption systems at zabs = 1.1923, 1.7193, 1.8873, 1.8916, and 1.9410. The systems are optically thin and reveal multiple lines of different metal ions with the ionization potentials lying in the extreme ultraviolet (EUV) range (~1 Ryd to ~0.2 keV). For each system, the EUV SED of the underlying ionization field is reconstructed by means of a special technique developed for solving the inverse problem in spectroscopy. For the zabs = 1.8916 system, the analysis also involves the He I resonance lines of the Lyman series and the He iλ504 Å continuum, which are seen for the first time in any cosmic object except the Sun. Results: From one system to another, the SED of the ionizing continuum changes significantly, indicating that the intergalactic ionization field at z ≲ 2 fluctuates at the scale of at least Δz ~ 0.004. This is consistent with Δz ≲ 0.01 estimated from He II and H I Lyman-α forest measurements between the redshifts 2 and 3. A radiation intensity break by approximately an order of magnitude at E = 4 Ryd in SEDs restored for the zabs = 1.1923, 1.8873, 1.8916, and 1.9410 systems points to quasars as the main sources of the ionizing radiation. The SED variability is mostly caused by a small number of objects contributing at any given redshift to the ionizing background; at scales Δz ≳ 0.05, the influence of local radiation sources becomes significant. A remarkable SED restored for the zabs = 1.7193 system, with a sharp break shifted to E ~ 3.5 Ryd and a subsequent intensity decrease by ~1.5 dex, indicates a source with comparable inputs of both hard (active galactic nuclei, AGN) and soft (stellar) radiation components. Such a continuum can be emitted by (ultra) luminous infrared galaxies, many of which reveal both a strong AGN activity and intense star formation in the circumnuclear regions.
Physical exercise restores microvascular function in obese rats with metabolic syndrome.

PubMed

Machado, Marcus Vinicius; Vieira, Aline Bomfim; Nascimento, Alessandro Rodrigues; Martins, Rômulo Lanza; Daleprane, Julio Beltrame; Lessa, Marcos Adriano; Tibiriçá, Eduardo

2014-11-01

Obesity and metabolic syndrome are related to systemic functional microvascular alterations, including a significant reduction in microvessel density. The aim of this study was to investigate the effects of exercise training on functional capillary density in the skeletal muscle and skin of obese rats with metabolic syndrome. We used male Wistar-Kyoto rats that had been fed a standard commercial diet (CON) or high-fat diet (HFD) for 32 weeks. Animals receiving the HFD were randomly divided into sedentary (HFD+SED) and training groups (HFD+TR) at the 20(th) week. After 12 weeks of aerobic treadmill training, the maximal oxygen uptake (VO2max); hemodynamic, biochemical, and anthropometric parameters; and functional capillary density were assessed. In addition, a maximal exercise test was performed. Exercise training increased the VO2max (69 ± 3 mL/kg per min) and exercise tolerance (30 ± 1 min) compared with the HFD+SED (41 ± 6 mL/kg per min, P < 0.05 and 16 ± 1 min, P < 0.001) and with the CON (52 ± 7 mL/kg per min and 18 ± 1 min, P < 0.05) groups. The HFD+TR group also showed reduced retroperitoneal fat (0.03 ± 0.00 vs. 0.05 ± 0.00 gram/gram, P < 0.001), epididymal fat (0.01 ± 0.00 vs. 0.02 ± 0.00 gram/gram, P < 0.001), and systolic blood pressure (127 ± 2 vs. 150 ± 2 mmHg, P<0.001). The HFD+TR group also demonstrated improved glucose tolerance, as evaluated by an intraperitoneal glucose tolerance test, fasting plasma glucose levels (5.0 ± 0.1 vs. 6.4 ± 0.2 mmol/L, P<0.001) and fasting plasma insulin levels (26.5 ± 2.3 vs. 38.9 ± 3.7 μIU/mL, P < 0.05). Glucose tolerance did not differ between HFD+TR and CON groups. Exercise training also increased the number of spontaneously perfused capillaries in the skeletal muscle (252 ± 9 vs. 207 ± 9 capillaries/mm(2)) of the training group compared with that in the sedentary animals (260 ± 15 capillaries/mm(2)). These results demonstrate that exercise training reverses capillary rarefaction in our experimental model of metabolic syndrome and obesity.
The broad-band SEDs of four `hypervariable' AGN

NASA Astrophysics Data System (ADS)

Collinson, James S.; Ward, Martin J.; Lawrence, Andy; Bruce, Alastair; MacLeod, Chelsea L.; Elvis, Martin; Gezari, Suvi; Marshall, Philip J.; Done, Chris

2018-03-01

We present an optical-to-X-ray spectral analysis of four `hypervariable' AGN (HVAs) discovered by comparing Pan-STARRS data to that from the Sloan Digital Sky Survey over a 10 yr baseline (Lawrence et al.). There is some evidence that these objects are X-ray loud for their corresponding UV luminosities, but given that we measured them in a historic high state, it is not clear whether to take the high state or low state as typical of the properties of these HVAs. We estimate black hole masses based on Mg II and H α emission line profiles, and either the high- or low-state luminosities, finding mass ranges log (MBH/M⊙) = 8.2-8.8 and log (MBH/M⊙) = 7.9-8.3, respectively. We then fit energy-conserving models to the spectral energy distributions (SEDs), obtaining strong constraints on the bolometric luminosity and αOX. We compare the SED properties with a larger, X-ray selected AGN sample for both of these scenarios, and observe distinct groupings in spectral shape versus luminosity parameter space. In general, the SED properties are closer to normal if we assume that the low state is representative. This supports the idea that the large slow outbursts may be due to extrinsic effects (for example microlensing) as opposed to accretion rate changes, but a larger sample of HVAs is needed to be confident of this conclusion.
Relative Age Dating of Young Star Clusters from YSOVAR

NASA Astrophysics Data System (ADS)

Johnson, Chelen H.; Gibbs, John C.; Linahan, Marcella; Rebull, Luisa; Bernstein, Alexandra E.; Child, Sierra; Eakins, Emma; Elert, Julia T.; Frey, Grace; Gong, Nathaniel; Hedlund, Audrey R.; Karos, Alexandra D.; Medeiros, Emma M.; Moradi, Madeline; Myers, Keenan; Packer, Benjamin M.; Reader, Livia K.; Sorenson, Benjamin; Stefo, James S.; Strid, Grace; Sumner, Joy; Sundeen, Kiera A.; Taylor, Meghan; Ujjainwala, Zakir L.

2018-01-01

The YSOVAR (Young Stellar Object VARiability; Rebull et al. 2014) Spitzer Space Telescope observing program monitored a dozen star forming cores in the mid-infrared (3.6 and 4.5 microns). Rebull et al. (2014) placed these cores in relative age order based on numbers of YSO candidates in SED class bins (I, flat, II, III), which is based on the slope of the SED between 2 and 25 microns. PanSTARRS data have recently been released (Chambers et al. 2016); deep optical data are now available over all the YSOVAR clusters. We worked with eight of the YSOVAR targets (IC1396-N, AFGL 490, NGC 1333, Mon R2, GGD 12-15, L 1688, IRAS 20050+2720, and Ceph C) and the YSO candidates identified therein as part of YSOVAR (through their infrared colors or X-ray detections plus a star-like SED; see Rebull et al. 2014). We created and examined optical and NIR color-magnitude diagrams and color-color diagrams of these YSO candidates to determine if the addition of optical data contradicted or reinforced the relative age dating of the clusters obtained with SED class ratios.This project is a collaborative effort of high school students and teachers from three states. We analyzed data individually and later collaborated online to compare results. This project is the result of many years of work with the NASA/IPAC Teacher Archive Research Program (NITARP).
Constraints on the Location of γ-Ray Sample of Blazars with Radio Core-shift Measurements

NASA Astrophysics Data System (ADS)

Wu, Linhui; Wu, Qingwen; Yan, Dahai; Chen, Liang; Fan, Xuliang

2018-01-01

We model simultaneous or quasi-simultaneous multi-band spectral energy distributions (SEDs) for a sample of 25 blazars that have radio core-shift measurements, where a one-zone leptonic model and Markov chain Monte Carlo technique are adopted. In the SED fitting for 23 low-synchrotron-peaked (LSP) blazars, the seed photons from the broad-line (BLR) and molecular torus are considered respectively in the external Compton process. We find that the SED fitting with the seed photons from the torus are better than those utilizing BLR photons, which suggest that the γ-ray emitting region may be located outside the BLR. Assuming the magnetic field strength in the γ-ray emitting region as constrained from the SED fitting follows the magnetic field distribution as derived from the radio core-shift measurements (i.e., B{(R)≃ {B}1{pc}(R/1{pc})}-1, where R is the distance from the central engine and {B}1{pc} is the magnetic field strength at 1 pc), we further calculate the location of the γ-ray emitting region, {R}γ , for these blazars. We find that {R}γ ∼ 2× {10}4{R}{{S}}≃ 10 {R}{BLR} ({R}{{S}} is the Schwarzschild radius and {R}{BLR} is the BLR size), where {R}{BLR} is estimated from the broad-line luminosities using the empirical correlations obtained using the reverberation mapping methods.
Aerobic training reduces oxidative stress in skeletal muscle of rats exposed to air pollution and supplemented with chromium picolinate.

PubMed

Marmett, Bruna; Nunes, Ramiro Barcos; de Souza, Kellen Sábio; Lago, Pedro Dal; Rhoden, Cláudia Ramos

2018-12-01

The purpose of this study was to investigate the effects of chromium picolinate (CrPic) supplementation associated with aerobic exercise using measures of oxidative stress in rats exposed to air pollution. Sixty-one male Wistar rats were divided into eight groups: residual oil fly ash (ROFA) exposure and sedentary (ROFA-SED); ROFA exposure, sedentary and supplemented (ROFA-SED-CrPic); ROFA exposure and trained (ROFA-AT); ROFA exposure, supplemented and trained (ROFA-AT-CrPic); sedentary (Sal-SED); sedentary and supplemented (Sal-SED-CrPic); trained (Sal-AT); and supplemented and trained (Sal-AT-CrPic). Rats exposed to ROFA (air pollution) received 50 µg of ROFA daily via intranasal instillation. Supplemented rats received CrPic (1 mg/kg/day) daily by oral gavage. Exercise training was performed on a rat treadmill (5×/week). Oxidative parameters were evaluated at the end of protocols. Trained groups demonstrated lower gain of body mass (P < .001) and increased exercise tolerance (P < .0001). In the gastrocnemius, trained groups demonstrated increased SOD activity (P < .0001) and decrease levels of TBARS (P = .0014), although CAT activity did not differ among groups (P = .4487). Air pollution exposure did not lead to alterations in oxidative markers in lungs and heart, and exercise training was responsible for decreasing oxidative stress of the gastrocnemius.
The SED-TOX: Toxicity-directed management tool to assess and rank sediments based on their hazard -- concept and application

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bombardier, M.; Bermingham, N.

1999-04-01

This article introduces the sediment Toxicity (SED-TOX) Index for the assessment and ranking of toxic hazards in sediment. Major features include expression of toxicity responses on a single scale of measurement (dry weight-based toxic units), consideration of multiple routes of exposure (pore water, organic extract, wet sediment, and whole sediment), application of differential treatments to toxicity data depending on the level of response, and use of weighting factors to discriminate sediment exposure phases and effect endpoints on the basis of sensitivity. A battery of seven bioassays with four test species (Vibrio fischeri, Escherichia coli, Lytechinus pictus, and Amphiporeia virginiana) wasmore » conducted on 49 marine sediment samples collected from six sites at Anse-a-Beaufils and Cap-aux-Meules, which are in the Gulf of St. Lawrence. The SED-TOX scores were calculated for each sampling station and compared with sediment contaminant concentrations. Results indicate that physico-chemical characterization is not sufficient to assess contaminated-sediment hazard for organisms; furthermore, using several exposure phases and test species belonging to various trophic levels increases the possibility of correctly identifying toxic sediments. The results of this study indicate that the SED-TOX approach is valuable as a toxicity assessment and ranking tool for sediments. It could easily be combined with other measures of ecosystem disturbance to discriminate between polluted and unpolluted sites.« less
From SED HI concept to Pleiades FM detection unit measurements

NASA Astrophysics Data System (ADS)

Renard, Christophe; Dantes, Didier; Neveu, Claude; Lamard, Jean-Luc; Oudinot, Matthieu; Materne, Alex

2017-11-01

The first flight model PLEIADES high resolution instrument under Thales Alenia Space development, on behalf of CNES, is currently in integration and test phases. Based on the SED HI detection unit concept, PLEIADES detection unit has been fully qualified before the integration at telescope level. The main radiometric performances have been measured on engineering and first flight models. This paper presents the results of performances obtained on the both models. After a recall of the SED HI concept, the design and performances of the main elements (charge coupled detectors, focal plane and video processing unit), detection unit radiometric performances are presented and compared to the instrument specifications for the panchromatic and multispectral bands. The performances treated are the following: - video signal characteristics, - dark signal level and dark signal non uniformity, - photo-response non uniformity, - non linearity and differential non linearity, - temporal and spatial noises regarding system definitions PLEIADES detection unit allows tuning of different functions: reference and sampling time positioning, anti-blooming level, gain value, TDI line number. These parameters are presented with their associated criteria of optimisation to achieve system radiometric performances and their sensitivities on radiometric performances. All the results of the measurements performed by Thales Alenia Space on the PLEIADES detection units demonstrate the high potential of the SED HI concept for Earth high resolution observation system allowing optimised performances at instrument and satellite levels.
The Stellar Mass of M31 as inferred by the Andromeda Optical & Infrared Disk Survey

NASA Astrophysics Data System (ADS)

Sick, Jonathan; Courteau, Stephane; Cuillandre, Jean-Charles; Dalcanton, Julianne; de Jong, Roelof; McDonald, Michael; Simard, Dana; Tully, R. Brent

2015-04-01

Our proximity and external vantage point make M31 an ideal testbed for understanding the structure of spiral galaxies. The Andromeda Optical and Infrared Disk Survey (ANDROIDS) has mapped M31's bulge and disk out to R=40 kpc in ugriJKs bands with CFHT using a careful sky calibration. We use Bayesian modelling of the optical-infrared spectral energy distribution (SED) to estimate profiles of M31's stellar populations and mass along the major axis. This analysis provides evidence for inside-out disk formation and a declining metallicity gradient. M31's i-band mass-to-light ratio (M/Li *) decreases from 0.5 dex in the bulge to ~ 0.2 dex at 40 kpc. The best-constrained stellar population models use the full ugriJKs SED but are also consistent with optical-only fits. Therefore, while NIR data can be successfully modelled with modern stellar population synthesis, NIR data do not provide additional constraints in this application. Fits to the gi-SED alone yield M/Li * that are systematically lower than the full SED fit by 0.1 dex. This is still smaller than the 0.3 dex scatter amongst different relations for M/Li via g - i colour found in the literature. We advocate a stellar mass of M *(30 kpc) = 10.3+2.3 -1.7 × 1010 M⊙ for the M31 bulge and disk.
Submillimeter Observations of the Low-Metallicity Galaxy NGC 4214

NASA Astrophysics Data System (ADS)

Kiuchi, Gaku; Ohta, Kouji; Sawicki, Marcin; Allen, Michael

2004-12-01

Results of submillimeter (450 and 850 μm) observations of a nearby dwarf irregular galaxy NGC 4214 with SCUBA on JCMT are presented. We aimed at examining the far-infrared-to-submillimeter spectral energy distribution (SED) and properties of dust thermal emission in a low-metallicity environment by choosing NGC 4214, in which the gas metallicity (logO/H+12) is 8.34. We found that the SED is quite similar to those of the IRAS Bright Galaxies Sample (IBGS), which are local bright star-forming galaxies with metallicities comparable to the solar abundance. The dust temperature and emissivity index for NGC 4214 obtained by a fitting to the single temperature graybody model are Td=35+/-0.8 K and β=1.4+/-0.1, respectively, which are typical values for IBGS galaxies. Compiling the previous studies on similar nearby dwarf irregular galaxies, we found that NGC 1569 shows similar results to those of NGC 4214, while NGC 4449 and IC 10 SE show different SEDs and low emissivity indices. There seems to be a variety of SEDs among metal-poor dwarf irregular galaxies. We examined the dependence on the intensity of interstellar radiation field, as well as a two-temperature model, but the origin of the difference is not clear. Some mechanism(s) other than metallicity and the interstellar radiation field must be responsible for controlling dust emission properties.
Tracing the energetics and evolution of dust with Spitzer: a chapter in the history of the Eagle Nebula

NASA Astrophysics Data System (ADS)

Flagey, N.; Boulanger, F.; Noriega-Crespo, A.; Paladini, R.; Montmerle, T.; Carey, S. J.; Gagné, M.; Shenoy, S.

2011-07-01

Context. The Spitzer GLIMPSE and MIPSGAL surveys have revealed a wealth of details about the Galactic plane in the infrared (IR) with orders of magnitude higher sensitivity, higher resolution, and wider coverage than previous IR observations. The structure of the interstellar medium (ISM) is tightly connected to the countless star-forming regions. We use these surveys to study the energetics and dust properties of the Eagle Nebula (M 16), one of the best known star-forming regions. Aims: We present MIPSGAL observations of M 16 at 24 and 70 μm and combine them with previous IR data. The mid-IR image shows a shell inside the well-known molecular borders of the nebula, as in the ISO and MSX observations from 15 to 21 μm. The morphologies at 24 and 70 μm are quite different, and its color ratio is unusually warm. The far-IR image resembles the one at 8 μm that enhances the structure of the molecular cloud and the "pillars of creation". We use this set of IR data to analyze the dust energetics and properties within this template for Galactic star-forming regions. Methods: We measure IR spectral energy distributions (SEDs) across the entire nebula, both within the inner shell and the photodissociation regions (PDRs). We use the DUSTEM model to fit these SEDs and constrain the dust temperature, the dust-size distribution, and the radiation field intensity relative to that provided by the star cluster NGC 6611 (χ/χ0). Results: Within the PDRs, the inferred dust temperature (~35 K), the dust-size distribution, and the radiation field intensity (χ/χ0 < 1) are consistent with expectations. Within the inner shell, the dust is hotter (~70 K). Moreover, the radiation field required to fit the SED is larger than that provided by NGC 6611 (χ/χ0 > 1). We quantify two solutions to this problem: (1) The size distribution of the dust in the shell is not that of interstellar dust. There is a significant enhancement of the carbon dust-mass in stochastically heated very small grains. (2) The dust emission arises from a hot (~106 K) plasma where both UV and collisions with electrons contribute to the heating. Within this hypothesis, the shell SED may be fit for a plasma pressure p/k ~ 5 × 107 K cm-3. Conclusions: We suggest two interpretations for the M 16 inner shell: (1) The shell matter is supplied by photo-evaporative flows arising from dense gas exposed to ionized radiation. The flows renew the shell matter as it is pushed out by the pressure from stellar winds. Within this scenario, we conclude that massive-star forming regions such as M 16 have a major impact on the carbon dust-size distribution. The grinding of the carbon dust could result from shattering in grain-grain collisions within shocks driven by the dynamical interaction between the stellar winds and the shell. (2) We also consider a more speculative scenario where the shell is a supernova remnant. In this case, we would be witnessing a specific time in the evolution of the remnant where the plasma pressure and temperature would enable the remnant to cool through dust emission.
Determining the sources of fine-grained sediment using the Sediment Source Assessment Tool (Sed_SAT)

USGS Publications Warehouse

Gorman Sanisaca, Lillian E.; Gellis, Allen C.; Lorenz, David L.

2017-07-27

A sound understanding of sources contributing to instream sediment flux in a watershed is important when developing total maximum daily load (TMDL) management strategies designed to reduce suspended sediment in streams. Sediment fingerprinting and sediment budget approaches are two techniques that, when used jointly, can qualify and quantify the major sources of sediment in a given watershed. The sediment fingerprinting approach uses trace element concentrations from samples in known potential source areas to determine a clear signature of each potential source. A mixing model is then used to determine the relative source contribution to the target suspended sediment samples.The computational steps required to apportion sediment for each target sample are quite involved and time intensive, a problem the Sediment Source Assessment Tool (Sed_SAT) addresses. Sed_SAT is a user-friendly statistical model that guides the user through the necessary steps in order to quantify the relative contributions of sediment sources in a given watershed. The model is written using the statistical software R (R Core Team, 2016b) and utilizes Microsoft Access® as a user interface but requires no prior knowledge of R or Microsoft Access® to successfully run the model successfully. Sed_SAT identifies outliers, corrects for differences in size and organic content in the source samples relative to the target samples, evaluates the conservative behavior of tracers used in fingerprinting by applying a “Bracket Test,” identifies tracers with the highest discriminatory power, and provides robust error analysis through a Monte Carlo simulation following the mixing model. Quantifying sediment source contributions using the sediment fingerprinting approach provides local, State, and Federal land management agencies with important information needed to implement effective strategies to reduce sediment. Sed_SAT is designed to assist these agencies in applying the sediment fingerprinting approach to quantify sediment sources in the sediment TMDL framework.
Modeling catchment nutrients and sediment loads to inform regional management of water quality in coastal-marine ecosystems: a comparison of two approaches.

PubMed

Álvarez-Romero, Jorge G; Wilkinson, Scott N; Pressey, Robert L; Ban, Natalie C; Kool, Johnathan; Brodie, Jon

2014-12-15

Human-induced changes in flows of water, nutrients, and sediments have impacts on marine ecosystems. Quantifying these changes to systematically allocate management actions is a priority for many areas worldwide. Modeling nutrient and sediment loads and contributions from subcatchments can inform prioritization of management interventions to mitigate the impacts of land-based pollution on marine ecosystems. Among the catchment models appropriate for large-scale applications, N-SPECT and SedNet have been used to prioritize areas for management of water quality in coastal-marine ecosystems. However, an assessment of their relative performance, parameterization, and utility for regional-scale planning is needed. We examined how these considerations can influence the choice between the two models and the areas identified as priorities for management actions. We assessed their application in selected catchments of the Gulf of California, where managing land-based threats to marine ecosystems is a priority. We found important differences in performance between models. SedNet consistently estimated spatial variations in runoff with higher accuracy than N-SPECT and modeled suspended sediment (TSS) loads mostly within the range of variation in observed loads. N-SPECT overestimated TSS loads by orders of magnitude when using the spatially-distributed sediment delivery ratio (SDR), but outperformed SedNet when using a calibrated SDR. Differences in subcatchments' contribution to pollutant loads were principally due to explicit representation of sediment sinks and particulate nutrients by SedNet. Improving the floodplain extent model, and constraining erosion estimates by local data including gully erosion in SedNet, would improve results of this model and help identify effective management responses. Differences between models in the patterns of modeled pollutant supply were modest, but significantly influenced the prioritization of subcatchments for management. Copyright © 2014 Elsevier Ltd. All rights reserved.
The First GeV Outburst of the Radio-loud Narrow-line Seyfert 1 Galaxy PKS 1502+036

NASA Astrophysics Data System (ADS)

Paliya, Vaidehi S.; Stalin, C. S.

2016-03-01

The γ-ray-loud narrow-line Seyfert 1 (γ-NLSy1) galaxy PKS 1502+036 (z = 0.409) exhibited its first γ-ray outburst on 2015 December 20. In the energy range of 0.1-300 GeV, the highest flux measured by the Fermi-Large Area Telescope is (3.90 ± 1.52) × 10-6 {ph} {{cm}}-2 {{{s}}}-1, which is the highest γ-ray flux ever detected from this object. The associated spectral shape is soft (Γ0.1-300 GeV = 2.57 ± 0.17) and this corresponds to an isotropic γ-ray luminosity of (1.2 ± 0.6) × 1048 erg s-1. We generate the broadband spectral energy distribution (SED) during the GeV flare and reproduce it using a one-zone leptonic emission model. The optical-UV spectrum can be explained by a combination of synchrotron and accretion disk emission, whereas the X-ray-to-γ-ray SED can be satisfactorily reproduced by inverse-Compton scattering of thermal photons that originated from the torus. The derived SED parameters hint that the increase in the bulk Lorentz factor is a major cause of the flare and the location of the emission region is estimated as being outside the broad-line region but still inside the torus. A comparison of the GeV-flaring SED of PKS 1502+036 with that of two other γ-NLSy1 galaxies, namely, 1H 0323+342 (z = 0.061) and PMN J0948+0022 (z = 0.585), and also with flat spectrum radio quasar (FSRQ) 3C 279 (z = 0.536), has led to the conclusion that the GeV-flaring SEDs of γ-NLSy1 galaxies resemble FSRQs and a major fraction of their bolometric luminosities are emitted at γ-ray energies.
Co-ingestion of carbohydrate and whey protein increases fasted rates of muscle protein synthesis immediately after resistance exercise in rats

PubMed Central

Wang, Wanyi; Ding, Zhenping; Solares, Geoffrey J.; Choi, Soon-Mi; Wang, Bo; Yoon, Aram; Farrar, Roger P.; Ivy, John L.

2017-01-01

The objective of the study was to investigate whether co-ingestion of carbohydrate and protein as compared with protein alone augments muscle protein synthesis (MPS) during early exercise recovery. Two months old rats performed 10 repetitions of ladder climbing with 75% of body weight attached to their tails. Placebo (PLA), whey protein (WP), or whey protein plus carbohydrate (CP) was then given to rats by gavage. An additional group of sedentary rats (SED) was used as controls. Blood samples were collected immediately and at either 1 or 2 h after exercise. The flexor hallucis longus muscle was excised at 1 or 2 h post exercise for analysis of MPS and related signaling proteins. MPS was significantly increased by CP compared with PLA (p<0.05), and approached significance compared with WP at 1 h post exercise (p = 0.08). CP yielded a greater phosphorylation of mTOR compared with SED and PLA at 1 h post exercise and SED and WP at 2 h post exercise. CP also increased phosphorylation of p70S6K compared with SED at 1 and 2 h post exercise. 4E-BP1 phosphorylation was inhibited by PLA at 1 h but elevated by WP and CP at 2 h post exercise relative to SED. The phosphorylation of AMPK was elevated by exercise at 1 h post exercise, and this elevated level was sustained only in the WP group at 2 h. The phosphorylation of Akt, GSK3, and eIF2Bε were unchanged by treatments. Plasma insulin was transiently increased by CP at 1 h post exercise. In conclusion, post-exercise CP supplementation increases MPS post exercise relative to PLA and possibly WP, which may have been mediated by greater activation of the mTOR signaling pathway. PMID:28296942
Duration of Casual Sunlight Exposure Necessary for Adequate Vitamin D Status in Indian Men

PubMed Central

Patwardhan, Vivek G.; Mughal, Zulf M.; Chiplonkar, Shashi A.; Webb, Ann R.; Kift, Richard; Khadilkar, Vaman V.; Padidela, Raja; Khadilkar, Anuradha V.

2018-01-01

Objectives: To investigate the duration of casual sunlight ultraviolet-B (UVB) exposure required to maintain optimal Vitamin D status (25-hydroxyvitamin-D [25(OH)D]) >50 nmol/L in urban Indian men, using polysulfone (PSU) dosimeters and a sunlight exposure questionnaire. Methods: In healthy men (aged 40–60 years) from Pune (18.52° N, 73.86° E), India, serum 25(OH)D was measured using enzyme-linked immunosorbent assay. Sunlight exposure was assessed using PSU dosimeter and by questionnaire. Results: Of 160 men (48.3 ± 5.6 years), 26.8% were deficient and 40.6% had insufficient Vitamin D concentrations. A hyperbolic function for the relationship between PSU measured sunlight exposure in standard erythema dose (SED) and serum 25(OH)D concentrations (r = 0.87, P < 0.01) revealed that daily exposure of 1 SED was sufficient to maintain serum 25(OH)D concentrations over 50 nmol/L. The curve plateaued around 5 SED (80 nmol/L) and extrapolation of the curve (>5 SED) did not increase 25(OH)D concentrations above 90 nmol/L. Receiver operating curve analysis confirmed that 1 SED-UV exposure was sufficient to maintain 25(OH)D concentrations over 50 nmol/L. Based on the questionnaire data, >1 h of midday casual sunlight exposure was required to maintain serum 25(OH)D concentrations above 50 nmol/L. Duration of sunlight exposure assessed by questionnaire and PSU dosimeter showed a significant correlation (r = 0.517, P < 0.01). Conclusion: In urban Indian men, >1 h of casual midday sunlight exposure daily was required to maintain serum 25(OH)D concentrations above 50 nmol/L, and >2 h of casual sunlight exposure was needed to maintain 25(OH)D concentrations above 75 nmol/L. Excess sunlight did not increase 25(OH)D linearly. The sunlight exposure questionnaire was validated for use in clinical studies and surveys.
AGN contamination in total infrared determined star formation rates in dusty galaxies at z~2-3

NASA Astrophysics Data System (ADS)

Mazzei, Renato; Sharon, Chelsea E.; Riechers, Dominik

2017-01-01

Along with theoretical work that suggests feedback from active galactic nuclei (AGN) may quench star formation in massive galaxies, the temporal coincidence between the peak of cosmic star formation rates and black hole accretion rates suggests that AGN are common in star forming galaxies at z~2-3. Since star forming galaxies at these epochs are also very dusty, it is important that we correct galaxies’ long-wavelength properties for the presence of dust-obscured AGN in order to accurately capture their star formation rates and gas characteristics. We present a spectral energy distribution (SED) analysis of several un-lensed z~2-3 dusty star-forming galaxies from Pope et al. (2008) and Coppin et al. (2010), which we compare to several other high-z starbursts with well sampled SEDs. We constructed dust SEDs from existing Spitzer, Herschel, and SCUBA-2 photometry catalogues with data between 3.6 and 850 μm. For the SED fits, we used the Code Investigating GALaxy Emission (CIGALE), since it self-consistently determines the dust attenuation of stars and dust emission in the infrared in addition to determining the dust emission from obscured AGN (Noll et al. 2009; Serra et al. 2011). Our best-fit SEDs have typical reduced χ2 values between 0.2 and ~3. We use the output from CIGALE to determine the fraction of the total infrared luminosity (LTIR 8-1000 um) from star formation and from any potential obscured AGN. In order to examine the effects of buried AGN on the integrated Schmidt-Kennicutt relation (log(LTIR) vs. log(L'CO)), we compare our new LTIR to recently obtained CO(1-0) line luminosities from the Karl G. Jansky Very Large Array. Unaccounted for dust emission from AGN can artificially inflate the star formation rate inferred from LTIR, and may therefore offset starburst galaxies from the local Schmidt-Kennicutt relation and increase the slope of the relation, which can affect the inferred drivers of star formation.
Plasma Interactions With a Negative Biased Electrodynamic Tether

NASA Technical Reports Server (NTRS)

Vaughn, Jason A.; Curtis, Leslie; Welzyn, Ken J.

2004-01-01

The ProSEDS conductive tether design incorporates two distinct types of tethers from a plasma interaction viewpoint. The 200 m closest to the Delta II spacecraft is insulated from the plasma, and the remaining 4800 m is semi-bare. This latter portion is considered semi-bare because a conductive coating, which is designed to collect electrons from the plasma, was applied to the wires to regulate the overall tether temperature. Because the tether has both insulating and conductive tether sections, a transition point exists between the two that forms a triple point with the space plasma. Also, insulated tethers can arc to the space plasma if the insulation is weakened or breached by pinholes caused by either improper handling or small meteoroid and orbital debris strikes. Because electrodynamic tethers are typically long, they have a high probability of these impacts. The particles, which strike the tether, may not have sufficient size to severe the tether, but they can easily penetrate the tether insulation producing a plasma discharge to the ambient plasma. Samples of both the ProSEDS tether transition region and the insulated tether section with various size of pinholes were placed into the MSFC plasma chamber and biased to typical ProSEDS open circuit tether potentials (-500 V to -1600 V). The results of the testing showed that the transition region of the tether (i.e. the triple point) arced to the ambient plasma at -900 V, and the tethers damaged by a pinhole or simulated debris strike arced to the plasma between -700 V and -900 V. Specific design steps were taken to eliminate the triple point issue in the ProSEDS tether design and make it ready for flight. To reduce the pinhole arcing risk, ProSEDS mission operations were changed to eliminate the high negative potential on the insulated tether. The results of the testing campaign and the design changes implemented to ensure a successful flight are described.
Development of a time-stepping sediment budget model for assessing land use impacts in large river basins.

PubMed

Wilkinson, S N; Dougall, C; Kinsey-Henderson, A E; Searle, R D; Ellis, R J; Bartley, R

2014-01-15

The use of river basin modelling to guide mitigation of non-point source pollution of wetlands, estuaries and coastal waters has become widespread. To assess and simulate the impacts of alternate land use or climate scenarios on river washload requires modelling techniques that represent sediment sources and transport at the time scales of system response. Building on the mean-annual SedNet model, we propose a new D-SedNet model which constructs daily budgets of fine sediment sources, transport and deposition for each link in a river network. Erosion rates (hillslope, gully and streambank erosion) and fine sediment sinks (floodplains and reservoirs) are disaggregated from mean annual rates based on daily rainfall and runoff. The model is evaluated in the Burdekin basin in tropical Australia, where policy targets have been set for reducing sediment and nutrient loads to the Great Barrier Reef (GBR) lagoon from grazing and cropping land. D-SedNet predicted annual loads with similar performance to that of a sediment rating curve calibrated to monitored suspended sediment concentrations. Relative to a 22-year reference load time series at the basin outlet derived from a dynamic general additive model based on monitoring data, D-SedNet had a median absolute error of 68% compared with 112% for the rating curve. RMS error was slightly higher for D-SedNet than for the rating curve due to large relative errors on small loads in several drought years. This accuracy is similar to existing agricultural system models used in arable or humid environments. Predicted river loads were sensitive to ground vegetation cover. We conclude that the river network sediment budget model provides some capacity for predicting load time-series independent of monitoring data in ungauged basins, and for evaluating the impact of land management on river sediment load time-series, which is challenging across large regions in data-poor environments. © 2013. Published by Elsevier B.V. All rights reserved.
Spectral Irradiance Calibration in the Infrared. XVII. Zero-Magnitude Broadband Flux Reference for Visible-to-Infrared Photometry

DTIC Science & Technology

2010-12-01

Air Force Reseach Laboratory, Hanscom AFB, MA 928, 2010 December © 2010, The American Astronomical Society. 14. ABSTRACT The absolutely calibrated...the visible and Sirius (a CMa) in the infrared. The resulting zero-point SED tests well against solar analog data presented by Rieke et al. while also...resulting zero-point SED tests well against solar analog data presented by Rieke et al. while also maintaining an unambiguous link to specific

The Propulsive Small Expendable Deployer System (ProSEDS)

NASA Technical Reports Server (NTRS)

Lorenzini, Enrico C.; Estes, Robert D.; Cosmo, Mario L.

2001-01-01

This is the Annual Report #2 entitled "The Propulsive Small Expendable Deployer System (ProSEDS)" prepared by the Smithsonian Astrophysical Observatory for NASA Marshall Space Flight Center. This report covers the period of activity from 1 August 2000 through 30 July 2001. The topics include: 1) Updated System Performance; 2) Mission Analysis; 3) Updated Dynamics Reference Mission; 4) Updated Deployment Control Profiles and Simulations; 5) Comparison of ED tethers and electrical thrusters; 6) Kalman filters for mission estimation; and 7) Delivery of interactive software for ED tethers.
Translations on Eastern Europe: Political, Sociological and Military Affairs No. 1604

DTIC Science & Technology

1978-11-03

CSSR---An SED study delegation led by H. Scheibe, member of the Central Committee and head of an SED Central Committee department, ar- rived in...just as crazy about literature as the birthday child is. And then there is on who had wanted to study but is now glad that he can work in the theater... studying Germanics. Altogether about 15 young people, all between 20 and 25 years of age. One .of them lives in the southern outskirts. In order to
Measurement of acceleration while walking as an automated method for gait assessment in dairy cattle.

PubMed

Chapinal, N; de Passillé, A M; Pastell, M; Hänninen, L; Munksgaard, L; Rushen, J

2011-06-01

The aims were to determine whether measures of acceleration of the legs and back of dairy cows while they walk could help detect changes in gait or locomotion associated with lameness and differences in the walking surface. In 2 experiments, 12 or 24 multiparous dairy cows were fitted with five 3-dimensional accelerometers, 1 attached to each leg and 1 to the back, and acceleration data were collected while cows walked in a straight line on concrete (experiment 1) or on both concrete and rubber (experiment 2). Cows were video-recorded while walking to assess overall gait, asymmetry of the steps, and walking speed. In experiment 1, cows were selected to maximize the range of gait scores, whereas no clinically lame cows were enrolled in experiment 2. For each accelerometer location, overall acceleration was calculated as the magnitude of the 3-dimensional acceleration vector and the variance of overall acceleration, as well as the asymmetry of variance of acceleration within the front and rear pair of legs. In experiment 1, the asymmetry of variance of acceleration in the front and rear legs was positively correlated with overall gait and the visually assessed asymmetry of the steps (r ≥ 0.6). Walking speed was negatively correlated with the asymmetry of variance of the rear legs (r=-0.8) and positively correlated with the acceleration and the variance of acceleration of each leg and back (r ≥ 0.7). In experiment 2, cows had lower gait scores [2.3 vs. 2.6; standard error of the difference (SED)=0.1, measured on a 5-point scale] and lower scores for asymmetry of the steps (18.0 vs. 23.1; SED=2.2, measured on a continuous 100-unit scale) when they walked on rubber compared with concrete, and their walking speed increased (1.28 vs. 1.22 m/s; SED=0.02). The acceleration of the front (1.67 vs. 1.72 g; SED=0.02) and rear (1.62 vs. 1.67 g; SED=0.02) legs and the variance of acceleration of the rear legs (0.88 vs. 0.94 g; SED=0.03) were lower when cows walked on rubber compared with concrete. Despite the improvements in gait score that occurred when cows walked on rubber, the asymmetry of variance of acceleration of the front leg was higher (15.2 vs. 10.4%; SED=2.0). The difference in walking speed between concrete and rubber correlated with the difference in the mean acceleration and the difference in the variance of acceleration of the legs and back (r ≥ 0.6). Three-dimensional accelerometers seem to be a promising tool for lameness detection on farm and to study walking surfaces, especially when attached to a leg. Copyright © 2011 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.
X-ray Counterparts of Infrared Faint Radio Sources

NASA Astrophysics Data System (ADS)

Schartel, Norbert

2011-10-01

Infrared Faint Radio Sources (IFRS) are radio sources with extremely faint or even absent infrared emission in deep Spitzer Surveys. Models of their spectral energy distributions, the ratios of radio to infrared flux densities and their steep radio spectra strongly suggest that IFRS are AGN at high redshifts (2
Deriving Stellar Masses for the ALFALFA α.100 Sample

NASA Astrophysics Data System (ADS)

Hess, Logan; Cornell 2017 Summer REU

2018-01-01

For this project, we explore different methods of deriving the stellar masses of galaxies in the ALFALFA (Arecibo Legacy Fast ALFA) α.100 survey. In particular, we measure the effectiveness of SED (Spectral Energy Distribution) on the sample. SED fitting was preformed by MAGPHYS (Multi-wavelength Analysis of Galaxy Physical Properties), utilizing a wide range of photometry in the UV, optical, and IR bands. Photometry was taken from GALAX GR6/7 (UV), SDSS DR13 (optical), WISE All-Sky (near-IR), and Herschel PACS/SPIRE (far-IR). The efficiency of SED fitting increases with a broader range of photometry, however detection rates varied significantly across the different bands. Using a more “comprehensive” sample of galaxies, the GSWLC-A (GALAX, SDSS, WISE Legacy Catalog All-Sky Survey), we aimed to measure which combination of bands provided the largest sample return with the lowest amount of uncertainty, which could then be used to estimate the masses of the galaxies in the α.100 sample.
Medical School Performance of Socioeconomically Disadvantaged and Underrepresented Minority Students Matriculating after a Multiple Mini-Interview.

PubMed

Jerant, Anthony; Henderson, Mark C; Griffin, Erin; Talamantes, Efrain; Fancher, Tonya; Sousa, Francis; Franks, Peter

2018-01-01

Multiple Mini-Interviews (MMIs) are increasingly used in medical school admissions. We previously reported that while under-represented minority (URM) status was not associated with MMI scores, self-designated disadvantaged applicants had lower MMI scores, possibly affecting their matriculation prospects. No studies have examined how URM status or socioeconomic disadvantage (SED) are associated with academic performance following admission through an MMI. We examined the adjusted associations of MMI scores, SED, and URM status with U.S. Medical Licensing Examination Steps 1 and 2 performance and third-year clerkship Honors, measures affecting residency matching. While URM status was not associated with the measures, students with greater SED had lower Step 1 scores and fewer Honors. Students with higher MMI scores had more Step 1 failures, but more Honors. The findings identify areas to address in medical school admissions, student support, and evaluation processes, which is important given the need for a more representative physician workforce.
THE SWIFT BAT SURVEY DETECTS TWO OPTICAL BROAD LINE, X-RAY HEAVILY OBSCURED ACTIVE GALAXIES: NVSS 193013+341047 AND IRAS 05218-1212

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hogg, J. Drew; Winter, Lisa M.; Mushotzky, Richard F.

2012-06-20

The Swift Burst Alert Telescope (BAT) is discovering interesting new objects while monitoring the sky in the 14-195 keV band. Here we present the X-ray properties and spectral energy distributions (SEDs) for two unusual active galactic nucleus sources. Both NVSS 193013+341047 and IRAS 05218-1212 are absorbed, Compton-thin, but heavily obscured (N{sub H} {approx} 10{sup 23} cm{sup -2}), X-ray sources at redshifts <0.1. The SEDs reveal these galaxies to be very red, with high extinction in the optical and UV. A similar SED is seen for the extremely red objects (EROs) detected in the higher redshift universe. This suggests that thesemore » unusual BAT-detected sources are a low-redshift (z << 1) analog to EROs, which recent evidence suggests are a class of the elusive type II quasars. Studying the multi-wavelength properties of these sources may reveal the properties of their high-redshift counterparts.« less
A Correction for IUE UV Flux Distributions from Comparisons with CALSPEC

NASA Astrophysics Data System (ADS)

Bohlin, Ralph C.; Bianchi, Luciana

2018-04-01

A collection of spectral energy distributions (SEDs) is available in the Hubble Space Telescope (HST) CALSPEC database that is based on calculated model atmospheres for pure hydrogen white dwarfs (WDs). A much larger set (∼100,000) of UV SEDs covering the range (1150–3350 Å) with somewhat lower quality are available in the IUE database. IUE low-dispersion flux distributions are compared with CALSPEC to provide a correction that places IUE fluxes on the CALSPEC scale. While IUE observations are repeatable to only 4%–10% in regions of good sensitivity, the average flux corrections have a precision of 2%–3%. Our re-calibration places the IUE flux scale on the current UV reference standard and is relevant for any project based on IUE archival data, including our planned comparison of GALEX to the corrected IUE fluxes. IUE SEDs may be used to plan observations and cross-calibrate data from future missions, so the IUE flux calibration must be consistent with HST instrumental calibrations to the best possible precision.
Effects of binary stellar populations on direct collapse black hole formation

NASA Astrophysics Data System (ADS)

Agarwal, Bhaskar; Cullen, Fergus; Khochfar, Sadegh; Klessen, Ralf S.; Glover, Simon C. O.; Johnson, Jarrett

2017-06-01

The critical Lyman-Werner (LW) flux required for direct collapse blackholes (DCBH) formation, or Jcrit, depends on the shape of the irradiating spectral energy distribution (SED). The SEDs employed thus far have been representative of realistic single stellar populations. We study the effect of binary stellar populations on the formation of DCBH, as a result of their contribution to the LW radiation field. Although binary populations with ages > 10 Myr yield a larger LW photon output, we find that the corresponding values of Jcrit can be up to 100 times higher than single stellar populations. We attribute this to the shape of the binary SEDs as they produce a sub-critical rate of H- photodetaching 0.76 eV photons as compared to single stellar populations, reaffirming the role that H- plays in DCBH formation. This further corroborates the idea that DCBH formation is better understood in terms of a critical region in the H2-H- photodestruction rate parameter space, rather than a single value of LW flux.
An emergency dental service for students: 4-year findings.

PubMed

Sinclair, J; Wilson, N H

1997-06-01

To describe the arrangements for the provision of emergency dental services for students at the University of Manchester and to report data collected during the first four and a half years of the student emergency dental services (SEDS) unit based at the University Dental Hospital of Manchester. Data pertaining to every student attending SEDS since its inception were collected by means of questionnaire including provision to record diagnoses, treatment needs and the emergency care provided. The incidence of dental emergencies within the student population served by SEDS has been found to be 39 emergencies per 1000 students per annum, with the service being most heavily used by overseas students. Caries, pulpal pathology and failed restorations account for 46 per cent of the presenting emergencies, with pericoronitis (19 per cent) and other emergencies of periodontal origin (14 per cent) being common place. It is concluded that a student emergency dental service may be found to be an important element of student medical and related welfare services.
Young Blue Straggler Stars in the Galactic Field

NASA Astrophysics Data System (ADS)

Ekanayake, Gemunu; Wilhelm, Ronald

2018-06-01

In this study we present an analysis of a sample of field blue straggler (BS) stars that show high ultra violet emission in their spectral energy distributions (SED): indication of a hot white dwarf (WD) companion to BS. Using photometry available in the Sloan Digital Sky Survey (SDSS) and Galaxy Evolution Explorer (GALEX ) surveys we identified 80 stars with UV excess. To determine the parameter distributions (mass, temperature and age) of the WD companions, we developed a fitting routine that could fit binary model SEDs to the observed SED. Results from this fit indicate the need for a hot WD companion to provide the excess UV flux. The WD mass distribution peaks at ˜0.4 M⊙, suggesting the primary formation channel of field BSs is case B mass transfer, i.e. when the donor star is in red giant phase of its evolution. Based on stellar evolutionary models, we estimate the lower limit of the binary mass transfer efficiency to be β ˜ 0.5.
Cooperative photometric redshift estimation

NASA Astrophysics Data System (ADS)

Cavuoti, S.; Tortora, C.; Brescia, M.; Longo, G.; Radovich, M.; Napolitano, N. R.; Amaro, V.; Vellucci, C.

2017-06-01

In the modern galaxy surveys photometric redshifts play a central role in a broad range of studies, from gravitational lensing and dark matter distribution to galaxy evolution. Using a dataset of ~ 25,000 galaxies from the second data release of the Kilo Degree Survey (KiDS) we obtain photometric redshifts with five different methods: (i) Random forest, (ii) Multi Layer Perceptron with Quasi Newton Algorithm, (iii) Multi Layer Perceptron with an optimization network based on the Levenberg-Marquardt learning rule, (iv) the Bayesian Photometric Redshift model (or BPZ) and (v) a classical SED template fitting procedure (Le Phare). We show how SED fitting techniques could provide useful information on the galaxy spectral type which can be used to improve the capability of machine learning methods constraining systematic errors and reduce the occurrence of catastrophic outliers. We use such classification to train specialized regression estimators, by demonstrating that such hybrid approach, involving SED fitting and machine learning in a single collaborative framework, is capable to improve the overall prediction accuracy of photometric redshifts.
Quality and clinical supply considerations of Paediatric Investigation Plans for IV preparations-A case study with the FP7 CloSed project.

PubMed

Hanning, Sara M; Orlu Gul, Mine; Winslade, Jackie; Baarslag, Manuel A; Neubert, Antje; Tuleu, Catherine

2016-09-25

A Paediatric Investigation Plan (PIP) is a development plan that aims to ensure that sufficient data are obtained through studies in paediatrics to support the generation of marketing authorisation of medicines for children. This paper highlights some practical considerations and challenges with respect to PIP submissions and paediatric clinical trials during the pharmaceutical development phase, using the FP7-funded Clonidine for Sedation of Paediatric Patients in the Intensive Care Unit (CloSed) project as a case study. Examples discussed include challenges and considerations regarding formulation development, blinding and randomisation, product labelling and shipment and clinical trial requirements versus requirements for marketing authorisation. A significant quantity of information is required for PIP submissions and it is hoped that future applicants may benefit from an insight into some critical considerations and challenges faced in the CloSed project. Copyright © 2016 Elsevier B.V. All rights reserved.
Multi-wavelength observations of PKS 2142-75 during active and quiescent gamma-ray states

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dutka, Michael S.; Ojha, Roopesh; Pottschmidt, Katja

2013-12-04

Here, PKS 2142–75 (a.k.a. 2FGL J2147.4–7534) is a flat-spectrum radio quasar that was observed quasi-simultaneously by a suite of instruments across the electromagnetic spectrum during two flaring states in 2010 April and 2011 August as well as a quiescent state from 2011 December through 2012 January. The results of these campaigns and model spectral energy distributions (SEDs) from the active and quiescent states are presented. The SED model parameters of PKS 2142–75 indicate that the two flares of the source are created by unique physical conditions. SED studies of flat-spectrum radio quasars are beginning to indicate that there might bemore » two types of flares, those that can be described purely by changes in the electron distribution and those that require changes in other parameters, such as the magnetic field strength or the size of the emitting region.« less
Recovering Galaxy Properties Using Gaussian Process SED Fitting

NASA Astrophysics Data System (ADS)

Iyer, Kartheik; Awan, Humna

2018-01-01

Information about physical quantities like the stellar mass, star formation rates, and ages for distant galaxies is contained in their spectral energy distributions (SEDs), obtained through photometric surveys like SDSS, CANDELS, LSST etc. However, noise in the photometric observations often is a problem, and using naive machine learning methods to estimate physical quantities can result in overfitting the noise, or converging on solutions that lie outside the physical regime of parameter space.We use Gaussian Process regression trained on a sample of SEDs corresponding to galaxies from a Semi-Analytic model (Somerville+15a) to estimate their stellar masses, and compare its performance to a variety of different methods, including simple linear regression, Random Forests, and k-Nearest Neighbours. We find that the Gaussian Process method is robust to noise and predicts not only stellar masses but also their uncertainties. The method is also robust in the cases where the distribution of the training data is not identical to the target data, which can be extremely useful when generalized to more subtle galaxy properties.
MarsSedEx III: linking Computational Fluid Dynamics (CFD) and reduced gravity experiments

NASA Astrophysics Data System (ADS)

Kuhn, N. J.; Kuhn, B.; Gartmann, A.

2015-12-01

Nikolaus J. Kuhn (1), Brigitte Kuhn (1), and Andres Gartmann (2) (1) University of Basel, Physical Geography, Environmental Sciences, Basel, Switzerland (nikolaus.kuhn@unibas.ch), (2) Meteorology, Climatology, Remote Sensing, Environmental Sciences, University of Basel, Switzerland Experiments conducted during the MarsSedEx I and II reduced gravity experiments showed that using empirical models for sediment transport on Mars developed for Earth violates fluid dynamics. The error is caused by the interaction between runing water and sediment particles, which affect each other in a positive feedback loop. As a consequence, the actual flow conditions around a particle cannot be represented by drag coefficients derived on Earth. This study exmines the implications of such gravity effects on sediment movement on Mars, with special emphasis on the limits of sandstones and conglomerates formed on Earth as analogues for sedimentation on Mars. Furthermore, options for correctiong the errors using a combination of CFD and recent experiments conducted during the MarsSedEx III campaign are presented.
MAMBO observations at 240GHz of optically obscured Spitzer sources: source clumps and radio activity at high redshift

NASA Astrophysics Data System (ADS)

Andreani, P.; Magliocchetti, M.; de Zotti, G.

2010-01-01

Optically very faint (R > 25.5) sources detected by the Spitzer Space Telescope at 24μm represent a very interesting population at redshift z ~ (1.5-3). They exhibit strong clustering properties, implying that they are hosted by very massive haloes, and their mid-infrared emission could be powered by either dust-enshrouded star formation and/or by an obscured active galactic nucleus (AGN). We report observations carried out with the Max Planck Millimetre Bolometer (MAMBO) array at the IRAM 30-m antenna on Pico Veleta of a candidate protocluster with five optically obscured sources selected from the 24-μm Spitzer sample of the First-Look Survey. Interestingly, these sources appear to lie on a high-density filament aligned with the two radio jets of an AGN. Four out of five of the observed sources were detected. We combine these measurements with optical, infrared and radio observations to probe the nature of the candidate protocluster members. Our preliminary conclusions can be summarized as follows: the spectral energy distributions (SEDs) of all sources include both AGN and starburst contributions; the AGN contribution to the bolometric luminosities ranges between 14 and 26 per cent of the total. Such a contribution is enough for the AGN to dominate the emission at 5.8, 8 and 24μm, while the stellar component, inferred from SED fitting, prevails at 1.25mm and at λ < 4.5μm. The present analysis suggests a coherent interplay at high z between extended radio activity and the development of filamentary large-scale structures.
DOE Office of Scientific and Technical Information (OSTI.GOV)

Leistedt, Boris; Hogg, David W., E-mail: boris.leistedt@nyu.edu, E-mail: david.hogg@nyu.edu

We present a new method for inferring photometric redshifts in deep galaxy and quasar surveys, based on a data-driven model of latent spectral energy distributions (SEDs) and a physical model of photometric fluxes as a function of redshift. This conceptually novel approach combines the advantages of both machine learning methods and template fitting methods by building template SEDs directly from the spectroscopic training data. This is made computationally tractable with Gaussian processes operating in flux–redshift space, encoding the physics of redshifts and the projection of galaxy SEDs onto photometric bandpasses. This method alleviates the need to acquire representative training datamore » or to construct detailed galaxy SED models; it requires only that the photometric bandpasses and calibrations be known or have parameterized unknowns. The training data can consist of a combination of spectroscopic and deep many-band photometric data with reliable redshifts, which do not need to entirely spatially overlap with the target survey of interest or even involve the same photometric bands. We showcase the method on the i -magnitude-selected, spectroscopically confirmed galaxies in the COSMOS field. The model is trained on the deepest bands (from SUBARU and HST ) and photometric redshifts are derived using the shallower SDSS optical bands only. We demonstrate that we obtain accurate redshift point estimates and probability distributions despite the training and target sets having very different redshift distributions, noise properties, and even photometric bands. Our model can also be used to predict missing photometric fluxes or to simulate populations of galaxies with realistic fluxes and redshifts, for example.« less
Modelling galaxy spectra in presence of interstellar dust - III. From nearby galaxies to the distant Universe

NASA Astrophysics Data System (ADS)

Cassarà, L. P.; Piovan, L.; Chiosi, C.

2015-07-01

Improving upon the standard evolutionary population synthesis technique, we present spectrophotometric models of galaxies with morphology going from spherical structures to discs, properly accounting for the effect of dust in the interstellar medium (ISM). The models contain three main physical components: the diffuse ISM made of gas and dust, the complexes of molecular clouds where active star formation occurs, and stars of any age and chemical composition. These models are based on robust evolutionary chemical description providing the total amount of gas and stars present at any age, and matching the properties of galaxies of different morphological types. We have considered the results obtained by Piovan et al. for the properties of the ISM, and those by Cassarà et al. for the spectral energy distribution (SED) of single stellar populations, both in presence of dust, to model the integral SEDs of galaxies of different morphological types, going from pure bulges to discs passing through a number of composite systems with different combinations of the two components. The first part of the paper is devoted to recall the technical details of the method and the basic relations driving the interaction between the physical components of the galaxy. Then, the main parameters are examined and their effects on the SED of three prototype galaxies are highlighted. The theoretical SEDs nicely match the observational ones both for nearby galaxies and those at high redshift.
Treadmill Exercise Prevents Increase of Neuroinflammation Markers Involved in the Dopaminergic Damage of the 6-OHDA Parkinson's Disease Model.

PubMed

Real, Caroline Cristiano; Garcia, Priscila Crespo; Britto, Luiz R G

2017-09-01

Parkinson's disease (PD) involves loss of dopaminergic neurons in the substantia nigra (SN), which can be correlated to neuroinflammatory changes with the aging of the nervous system. On the other hand, exercise can reduce the deleterious effects promoted by age, but the mechanism involved is still unclear. This study investigated the preventive exercise-induced changes on neuroinflammatory processes in a rat model of PD induced by unilateral striatal injections of 6-hydroxydopamine (6-OHDA). Adult male Wistar rats were divided into two groups: (1) sedentary (SED) or (2) exercised (EX), animals that did treadmill exercise three times per week, every other day, for 4 weeks prior to 6-OHDA or saline injection. The rats were then divided into four sub-groups: (1) sedentary saline (SED), (2) sedentary 6-OHDA (SED + 6-OHDA), (3) exercised saline (EX), and (4) exercised 6-OHDA (EX + 6-OHDA). Seven and 30 days after surgery, brains were collected for immunohistochemistry and immunoblotting for dopaminergic and neuroinflammatory markers into SN and striatum. The SED + 6-OHDA animals presented an increase in the astrocyte, microglial, and oxidative species activation. On the other hand, EX + 6-OHDA animals did not present neuroinflammatory responses and performed better apormorphine test. Our data suggest that treadmill exercise throughout life can markedly reduce the chances of dopamine decrease, reinforcing studies that showed a lower incidence of Parkinson's disease in patients who were active during life.

Mr-Moose: An advanced SED-fitting tool for heterogeneous multi-wavelength datasets

NASA Astrophysics Data System (ADS)

Drouart, G.; Falkendal, T.

2018-04-01

We present the public release of Mr-Moose, a fitting procedure that is able to perform multi-wavelength and multi-object spectral energy distribution (SED) fitting in a Bayesian framework. This procedure is able to handle a large variety of cases, from an isolated source to blended multi-component sources from an heterogeneous dataset (i.e. a range of observation sensitivities and spectral/spatial resolutions). Furthermore, Mr-Moose handles upper-limits during the fitting process in a continuous way allowing models to be gradually less probable as upper limits are approached. The aim is to propose a simple-to-use, yet highly-versatile fitting tool fro handling increasing source complexity when combining multi-wavelength datasets with fully customisable filter/model databases. The complete control of the user is one advantage, which avoids the traditional problems related to the "black box" effect, where parameter or model tunings are impossible and can lead to overfitting and/or over-interpretation of the results. Also, while a basic knowledge of Python and statistics is required, the code aims to be sufficiently user-friendly for non-experts. We demonstrate the procedure on three cases: two artificially-generated datasets and a previous result from the literature. In particular, the most complex case (inspired by a real source, combining Herschel, ALMA and VLA data) in the context of extragalactic SED fitting, makes Mr-Moose a particularly-attractive SED fitting tool when dealing with partially blended sources, without the need for data deconvolution.
An ALMA Survey of Submillimeter Galaxies in the Extended Chandra Deep Field South: Spectroscopic Redshifts

NASA Astrophysics Data System (ADS)

Danielson, A. L. R.; Swinbank, A. M.; Smail, Ian; Simpson, J. M.; Casey, C. M.; Chapman, S. C.; da Cunha, E.; Hodge, J. A.; Walter, F.; Wardlow, J. L.; Alexander, D. M.; Brandt, W. N.; de Breuck, C.; Coppin, K. E. K.; Dannerbauer, H.; Dickinson, M.; Edge, A. C.; Gawiser, E.; Ivison, R. J.; Karim, A.; Kovacs, A.; Lutz, D.; Menten, K.; Schinnerer, E.; Weiß, A.; van der Werf, P.

2017-05-01

We present spectroscopic redshifts of {\\text{}}{S}870μ {{m}} ≳ 2 mJy submillimeter galaxies (SMGs), which have been identified from the ALMA follow-up observations of 870 μm detected sources in the Extended Chandra Deep Field South (the ALMA-LESS survey). We derive spectroscopic redshifts for 52 SMGs, with a median of z = 2.4 ± 0.1. However, the distribution features a high-redshift tail, with ˜23% of the SMGs at z≥slant 3. Spectral diagnostics suggest that the SMGs are young starbursts, and the velocity offsets between the nebular emission and UV ISM absorption lines suggest that many are driving winds, with velocity offsets of up to 2000 km s-1. Using the spectroscopic redshifts and the extensive UV-to-radio photometry in this field, we produce optimized spectral energy distributions (SEDs) using Magphys, and use the SEDs to infer a median stellar mass of {M}\\star = (6 ± 1)× 1010 M {}⊙ for our SMGs with spectroscopic redshift. By combining these stellar masses with the star formation rates (measured from the far-infrared SEDs), we show that SMGs (on average) lie a factor of ˜5 above the so-called “main sequence” at z˜ 2. We provide this library of 52 template fits with robust and uniquely well-sampled SEDs as a resource for future studies of SMGs, and also release the spectroscopic catalog of ˜2000 (mostly infrared-selected) galaxies targeted as part of the spectroscopic campaign.
DOE Office of Scientific and Technical Information (OSTI.GOV)

Espaillat, C.; Andrews, S.; Qi, C.

Two decades ago 'transitional disks' (TDs) described spectral energy distributions (SEDs) of T Tauri stars with small near-IR excesses, but significant mid- and far-IR excesses. Many inferred this indicated dust-free holes in disks possibly cleared by planets. Recently, this term has been applied disparately to objects whose Spitzer SEDs diverge from the expectations for a typical full disk (FD). Here, we use irradiated accretion disk models to fit the SEDs of 15 such disks in NGC 2068 and IC 348. One group has a 'dip' in infrared emission while the others' continuum emission decreases steadily at all wavelengths. We findmore » that the former have an inner disk hole or gap at intermediate radii in the disk and we call these objects 'transitional disks' and 'pre-transitional disks' (PTDs), respectively. For the latter group, we can fit these SEDs with FD models and find that millimeter data are necessary to break the degeneracy between dust settling and disk mass. We suggest that the term 'transitional' only be applied to objects that display evidence for a radical change in the disk's radial structure. Using this definition, we find that TDs and PTDs tend to have lower mass accretion rates than FDs and that TDs have lower accretion rates than PTDs. These reduced accretion rates onto the star could be linked to forming planets. Future observations of TDs and PTDs will allow us to better quantify the signatures of planet formation in young disks.« less
MR-MOOSE: an advanced SED-fitting tool for heterogeneous multi-wavelength data sets

NASA Astrophysics Data System (ADS)

Drouart, G.; Falkendal, T.

2018-07-01

We present the public release of MR-MOOSE, a fitting procedure that is able to perform multi-wavelength and multi-object spectral energy distribution (SED) fitting in a Bayesian framework. This procedure is able to handle a large variety of cases, from an isolated source to blended multi-component sources from a heterogeneous data set (i.e. a range of observation sensitivities and spectral/spatial resolutions). Furthermore, MR-MOOSE handles upper limits during the fitting process in a continuous way allowing models to be gradually less probable as upper limits are approached. The aim is to propose a simple-to-use, yet highly versatile fitting tool for handling increasing source complexity when combining multi-wavelength data sets with fully customisable filter/model data bases. The complete control of the user is one advantage, which avoids the traditional problems related to the `black box' effect, where parameter or model tunings are impossible and can lead to overfitting and/or over-interpretation of the results. Also, while a basic knowledge of PYTHON and statistics is required, the code aims to be sufficiently user-friendly for non-experts. We demonstrate the procedure on three cases: two artificially generated data sets and a previous result from the literature. In particular, the most complex case (inspired by a real source, combining Herschel, ALMA, and VLA data) in the context of extragalactic SED fitting makes MR-MOOSE a particularly attractive SED fitting tool when dealing with partially blended sources, without the need for data deconvolution.
How best to assess suppression in patients with high anisometropia.

PubMed

Li, Jinrong; Hess, Robert F; Chan, Lily Y L; Deng, Daming; Chen, Xiang; Yu, Minbin; Thompson, Benjamin S

2013-02-01

We have recently described a rapid technique for measuring suppression using a dichoptic signal/noise task. Here, we report a modification of this technique that allows for accurate measurements to be made in amblyopic patients with high levels of anisometropia. This was necessary because aniseikonic image size differences between the two eyes can provide a cue for signal/noise segregation and, therefore, influence suppression measurement in these patients. Suppression was measured using our original technique and with a modified technique whereby the size of the signal and noise elements was randomized across the stimulus to eliminate size differences as a cue for task performance. Eleven patients with anisometropic amblyopia, five with more than 5 diopters (D) spherical equivalent difference (SED), six with less than 5 D SED between the eyes, and 10 control observers completed suppression measurements using both techniques. Suppression measurements in controls and patients with less than 5 D SED were constant across the two techniques; however, patients with more than 5 D SED showed significantly stronger suppression on the modified technique with randomized element size. Measurements made with the modified technique correlated with the loss of visual acuity in the amblyopic eye and were in good agreement with previous reports using detailed psychophysical measurements. The signal/noise technique for measuring suppression can be applied to patients with high levels of anisometropia and aniseikonia if element size is randomized. In addition, deeper suppression is associated with a greater loss of visual acuity in patients with anisometropic amblyopia.
Development of a New Zealand SedNet model for assessment of catchment-wide soil-conservation works

NASA Astrophysics Data System (ADS)

Dymond, John R.; Herzig, Alexander; Basher, Les; Betts, Harley D.; Marden, Mike; Phillips, Chris J.; Ausseil, Anne-Gaelle E.; Palmer, David J.; Clark, Maree; Roygard, Jon

2016-03-01

Much hill country in New Zealand has been converted from indigenous forest to pastoral agriculture, resulting in increased soil erosion. Following a severe storm that hit the Manawatu-Wanaganui region in 2004 and caused 62,000 landslides, the Horizons Regional Council have implemented the Sustainable Land Use Initiative (SLUI), a programme of widespread soil conservation. We have developed a New Zealand version (SedNetNZ) of the Australian SedNet model to evaluate the impact of the SLUI programme in the 5850 km2 Manawatu catchment. SedNetNZ spatially distributes budgets of fine sediment in the landscape. It incorporates landslide, gully, earthflow erosion, surficial erosion, bank erosion, and flood-plain deposition, the important forms of soil erosion in New Zealand. Modelled suspended sediment loads compared well with measured suspended sediment loads with an R2 value of 0.85 after log transformation. A sensitivity analysis gave the uncertainty of estimated suspended sediment loads to be approximately plus or minus 50% (at the 95% confidence level). It is expected that by 2040, suspended sediment loads in targeted water management zones will decrease by about 40%. The expected decrease for the whole catchment is 34%. The expected reduction is due to maturity of tree planting on land at risk to soil erosion. The 34% reduction represents an annual rate of return of 20% on 20 million NZ of investment on soil conservation works through avoided damage to property and infrastructure and avoided clean-up costs.
The spectral energy distribution of galaxies at z > 2.5: Implication from the Herschel/SPIRE color-color diagram

NASA Astrophysics Data System (ADS)

Yuan, Fangting; Buat, Veronique; Burgarella, Denis; Ciesla, Laure; Heinis, Sebastien; Shen, Shiyin; Shao, Zhengyi; Hou, Jinliang

2015-08-01

We use the Herschel SPIRE color-color diagram to study the spectral energy distribution (SED) and the redshift estimation of high-z galaxies. We collect a sample of 57 galaxies with spectroscopically confirmed redshifts and reliable flux measurements at redshift z=2.5-6.4, and compare their average SPIRE colors with SED templates from local and high-z libraries. We find that local SEDs are inconsistent with high-z observations. For the libraries of Chary & Elbaz (2001) and Dale & Helou (2002), the local calibrations of the parameters LIR and alpha need to be adjusted to around 1011Lsun and 1.5 to describe the average colors given by the observations. For high-z libraries, the templates of Magdis et al. (2012) can well describe the average colors of the observations at high redshift, justifying their assumption of an evolution of SED from z=0 to 3. Using the templates of Magdis et al. (2012), we defined color cuts to divide the SPIRE color-color diagram into different regions with different mean redshifts. We tested this method and two other color cut methods 500 micron risers and the method of Amblard et al. (2010) using a large sample of 786 Herschel-selected galaxies, and find that these color cut methods can separate the sample into populations with different mean redshifts, although the dispersion of redshifts in each population is quite large.
VOSA: SED building and analysis of thousands of stars in the framework of Gaia

NASA Astrophysics Data System (ADS)

Rodrigo, C.; Solano, E.; Bayo, A.

2014-07-01

VOSA (http://svo2.cab.inta-csic.es/theory/vosa/), is a web-based tool designed to combine private photometric measurements with data available in VO services distributed worldwide to build the observational spectral energy distributions (SEDs) of hundreds of objects. VOSA also accesses various collections of models to simulate the equivalent theoretical SEDs, allows the user to decide the range of physical parameters to explore, performs the SED comparison, provides the best fitting models to the user following two different approaches (chi square and Bayesian fitting), and, for stellar sources, compares these parameters with isochrones and evolutionary tracks to estimate masses and ages. In particular, VOSA offers the advantage of deriving physical parameters using all the available photometric information instead of a restricted subset of colors. VOSA was firstly released in 2008 and its functionalities are described in Bayo et al. (2008). At the time of writing there are more than 300 active users in VOSA who have published more than 60 refereed papers. In the framework of the GENIUS (https://gaia.am.ub.es/Twiki/bin/view/GENIUS) project we are upgrading VOSA to, on one hand, provide a seamless access to Gaia data and, on the other hand, handle thousands of objects at a time. In this poster, the main functionalities to be implemented in the Gaia context will be described. The poster can be found at: http://svo.cab.inta-csic.es/files/svo//Public/SVOPapers/posters/vosa-poster3.pdf.
Infrared Luminosities and Dust Properties of z ≈ 2 Dust-obscured Galaxies

NASA Astrophysics Data System (ADS)

Bussmann, R. S.; Dey, Arjun; Borys, C.; Desai, V.; Jannuzi, B. T.; Le Floc'h, E.; Melbourne, J.; Sheth, K.; Soifer, B. T.

2009-11-01

We present SHARC-II 350 μm imaging of twelve 24 μm bright (F 24 μm > 0.8 mJy) Dust-Obscured Galaxies (DOGs) and Combined Array for Research in Millimeter-wave Astronomy (CARMA) 1 mm imaging of a subset of two DOGs. These objects are selected from the Boötes field of the NOAO Deep Wide-Field Survey. Detections of four DOGs at 350 μm imply infrared (IR) luminosities which are consistent to within a factor of 2 of expectations based on a warm-dust spectral energy distribution (SED) scaled to the observed 24 μm flux density. The 350 μm upper limits for the 8 non-detected DOGs are consistent with both Mrk 231 and M82 (warm-dust SEDs), but exclude cold dust (Arp 220) SEDs. The two DOGs targeted at 1 mm were not detected in our CARMA observations, placing strong constraints on the dust temperature: T dust > 35-60 K. Assuming these dust properties apply to the entire sample, we find dust masses of ≈3 × 108 M sun. In comparison to other dusty z ~ 2 galaxy populations such as submillimeter galaxies (SMGs) and other Spitzer-selected high-redshift sources, this sample of DOGs has higher IR luminosities (2 × 1013 L sun versus 6 × 1012 L sun for the other galaxy populations) that are driven by warmer dust temperatures (>35-60 K versus ~30 K) and lower inferred dust masses (3 × 108 M sun versus 3 × 109 M sun). Wide-field Herschel and Submillimeter Common-User Bolometer Array-2 surveys should be able to detect hundreds of these power-law-dominated DOGs. We use the existing Hubble Space Telescope and Spitzer/InfraRed Array Camera data to estimate stellar masses of these sources and find that the stellar to gas mass ratio may be higher in our 24 μm bright sample of DOGs than in SMGs and other Spitzer-selected sources. Although much larger sample sizes are needed to provide a definitive conclusion, the data are consistent with an evolutionary trend in which the formation of massive galaxies at z ~ 2 involves a submillimeter bright, cold-dust, and star-formation-dominated phase followed by a 24 μm bright, warm-dust and AGN-dominated phase.
Quenching of the star formation activity in cluster galaxies

NASA Astrophysics Data System (ADS)

Boselli, A.; Roehlly, Y.; Fossati, M.; Buat, V.; Boissier, S.; Boquien, M.; Burgarella, D.; Ciesla, L.; Gavazzi, G.; Serra, P.

2016-11-01

We study the star formation quenching mechanism in cluster galaxies by fitting the spectral energy distribution (SED) of the Herschel Reference Survey, a complete volume-limited K-band-selected sample of nearby galaxies including objects in different density regions, from the core of the Virgo cluster to the general field. The SEDs of the target galaxies were fitted using the CIGALE SED modelling code. The truncated activity of cluster galaxies was parametrised using a specific star formation history with two free parameters, the quenching age QA and the quenching factor QF. These two parameters are crucial for the identification of the quenching mechanism, which acts on long timescales when starvation processes are at work, but is rapid and efficient when ram pressure occurs. To be sensitive to an abrupt and recent variation of the star formation activity, we combined twenty photometric bands in the UV to far-infrared in a new way with three age-sensitive Balmer line absorption indices extracted from available medium-resolution (R 1000) integrated spectroscopy and with Hα narrow-band imaging data. The use of a truncated star formation history significantly increases the quality of the fit in HI-deficient galaxies of the sample, that is to say, in those objects whose atomic gas content has been removed during the interaction with the hostile cluster environment. The typical quenching age of the perturbed late-type galaxies is QA ≲ 300 Myr whenever the activity of star formation is reduced by 50% < QF ≤ 80% and QA ≲ 500 Myr for QF > 80%, while that of the quiescent early-type objects is QA ≃ 1-3 Gyr. The fraction of late-type galaxies with a star formation activity reduced by QF > 80% and with an HI-deficiency parameter HI-def > 0.4 drops by a factor of 5 from the inner half virial radius of the Virgo cluster (R/Rvir < 0.5), where the hot diffuse X-ray emitting gas of the cluster is located, to the outer regions (R/Rvir > 4). The efficient quenching of the star formation activity observed in Virgo suggests that the dominant stripping process is ram pressure. We discuss the implication of this result in the cosmological context of galaxy evolution.
AGN neutrino flux estimates for a realistic hybrid model

NASA Astrophysics Data System (ADS)

Richter, S.; Spanier, F.

2018-07-01

Recent reports of possible correlations between high energy neutrinos observed by IceCube and Active Galactic Nuclei (AGN) activity sparked a burst of publications that attempt to predict the neutrino flux of these sources. However, often rather crude estimates are used to derive the neutrino rate from the observed photon spectra. In this work neutrino fluxes were computed in a wide parameter space. The starting point of the model was a representation of the full spectral energy density (SED) of 3C 279. The time-dependent hybrid model that was used for this study takes into account the full pγ reaction chain as well as proton synchrotron, electron-positron-pair cascades and the full SSC scheme. We compare our results to estimates frequently used in the literature. This allows to identify regions in the parameter space for which such estimates are still valid and those in which they can produce significant errors. Furthermore, if estimates for the Doppler factor, magnetic field, proton and electron densities of a source exist, the expected IceCube detection rate is readily available.
Psychometric Properties of the Sexual Event Diary in a Sample of Dutch Women With Female Sexual Interest/Arousal Disorder.

PubMed

van Nes, Yvonne; Bloemers, Jos; Kessels, Rob; van der Heijden, Peter G M; van Rooij, Kim; Gerritsen, Jeroen; DeRogatis, Leonard; Tuiten, Adriaan

2018-05-01

Efficacy of on-demand drugs for women with hypoactive sexual desire disorder or female sexual interest/arousal disorder (FSIAD) should be assessed using a validated instrument that assesses the discrete sexual events during which the on-demand drug is taken, because this type of assessment is more proximate to an on-demand drug's efficacy compared to instruments that assess sexual function over longer periods of time. The aim of this study was to assess the psychometric properties of the Dutch translation of the previously validated 11-item Sexual Event Diary (SED) for measuring sexual satisfaction and sexual functioning during discrete sexual events. Psychometric assessment was performed on data of 1,840 SEDs from 139 women with hypoactive sexual desire disorder/FSIAD, collected during a randomized clinical cross-over trial conducted in the Netherlands. Item scores of the SED at the event level, and at subject level, summarized item scores during the placebo run-in period (PRI) and active treatment period, and score changes from PRI to active treatment period. Reliability and convergent validity were confirmed. All item scores showed the ability to discriminate between known groups. Larger mean score changes from PRI were observed in groups with known benefit from the medication, as compared to those with no benefit. Guyatt effect sizes ranged from 0.51-1.02, thereby demonstrating ability to detect change. The Dutch version of the SED is an excellent instrument for assessing female sexual functioning and sexual satisfaction during discrete sexual events and for assessing these concepts over longer periods of time. Data were collected in a randomized, well-controlled trial. The large number of data points gave high statistical power, and the results confirmed previous findings. However, care is needed when generalizing the SED's validity to other areas of research, eg, recreational drug use and sexual risky behaviors, since the current validation study has not used such data. Consistent with the US-English version, the Dutch version of the SED is a reliable, valid, and responsive instrument, and suitable for use in evaluating effects of on-demand drugs in women with FSIAD. van Nes Y, Bloemers J, Kessels R, et al. Psychometric Properties of the Sexual Event Diary in a Sample of Dutch Women With Female Sexual Interest/Arousal Disorder. J Sex Med 2018;15:722-731. Copyright © 2018 International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.
LUMINOSITY FUNCTIONS OF SPITZER-IDENTIFIED PROTOSTARS IN NINE NEARBY MOLECULAR CLOUDS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kryukova, E.; Megeath, S. T.; Allen, T. S.

2012-08-15

We identify protostars in Spitzer surveys of nine star-forming (SF) molecular clouds within 1 kpc: Serpens, Perseus, Ophiuchus, Chamaeleon, Lupus, Taurus, Orion, Cep OB3, and Mon R2, which combined host over 700 protostar candidates. These clouds encompass a variety of SF environments, including both low-mass and high-mass SF regions, as well as dense clusters and regions of sparsely distributed star formation. Our diverse cloud sample allows us to compare protostar luminosity functions in these varied environments. We combine near- and mid-infrared photometry from the Two Micron All Sky Survey and Spitzer to create 1-24 {mu}m spectral energy distributions (SEDs). Usingmore » protostars from the c2d survey with well-determined bolometric luminosities, we derive a relationship between bolometric luminosity, mid-IR luminosity (integrated from 1-24 {mu}m), and SED slope. Estimations of the bolometric luminosities for protostar candidates are combined to create luminosity functions for each cloud. Contamination due to edge-on disks, reddened Class II sources, and galaxies is estimated and removed from the luminosity functions. We find that luminosity functions for high-mass SF clouds (Orion, Mon R2, and Cep OB3) peak near 1 L{sub Sun} and show a tail extending toward luminosities above 100 L{sub Sun }. The luminosity functions of the low-mass SF clouds (Serpens, Perseus, Ophiuchus, Taurus, Lupus, and Chamaeleon) do not exhibit a common peak, however the combined luminosity function of these regions peaks below 1 L{sub Sun }. Finally, we examine the luminosity functions as a function of the local surface density of young stellar objects. In the Orion molecular clouds, we find a significant difference between the luminosity functions of protostars in regions of high and low stellar density, the former of which is biased toward more luminous sources. This may be the result of primordial mass segregation, although this interpretation is not unique. We compare our luminosity functions to those predicted by models and find that our observed luminosity functions are best matched by models that invoke competitive accretion, although we do not find strong agreement between the high-mass SF clouds and any of the models.« less
The Distinct Build-Up Of Dense And Normal Massive Passive Galaxies In Vipers

NASA Astrophysics Data System (ADS)

Gargiulo, Adriana; Vipers Team

2017-06-01

At fixed stellar mass, the population of passive galaxies has increased its mean effective radius < Re > by a factor 5 in the last 10 Gyr, decreasing its mean stellar mass density (S = Mstar/(2πRe 2 ) by a factor >> 10. Whether this increase in < Re > is mainly due to the size-growth of individual galaxies through dry mergers, or to the fact that newly quenched galaxies have a larger size, is still matter of debate. A promising approach to shed light on this issue is to investigate the evolution of the number density of passive galaxies as a function of their mass density. In this context, massive (Mstar >10^11 Msun) passive galaxies are the most intriguing systems to study, since, in a hierarchical scenario, they are expected to accrete their stellar mass mainly by mergers. The wide area (˜ 16 sq. deg) and high sampling rate (˜ 40%) of the spectroscopic survey VIPERS allowed us to collect a sample of ˜ 2000 passive massive galaxies over the redshift range 0.5 < z < 1.0 and to study, with unprecedented statistics, the evolution of their number density as function of their mean stellar mass density in this redshift range. Taking advantage of both spectroscopic (D4000) and photometric (SED fitting) data available, we studied the age of the stellar population of passive galaxies as function both of redshift and mass density. This information, combined with the evolution of the number density allowed us to put constraints on the mass accretion scenarios of passive galaxies. In this talk I will present our results and conclusions and how they depend on the environment in which the galaxies reside.
Statistical characterization of the Sub-Auroral Polarization Stream (SAPS)

NASA Astrophysics Data System (ADS)

Kunduri, B.; Baker, J. B.; Ruohoniemi, J. M.; Erickson, P. J.; Coster, A. J.; Oksavik, K.

2017-12-01

The Sub-Auroral Polarization Stream (SAPS) is a narrow region of westward directed plasma convection typically observed in the dusk-midnight sector equatorward of the main auroral oval. SAPS plays an important role in mid-latitude space weather dynamics and has a controlling influence on the evolution of large-scale plasma features, such as Storm Enhanced Density (SED) plumes. In this study, data from North American mid-latitude SuperDARN radars collected between January 2011 and December 2014 have been used to compile a database of SAPS events for statistical analysis. We examine the dependence of SAPS velocity magnitude and direction on geomagnetic activity and magnetic local time. The lowest speed limit and electric fields observed during SAPS are discussed and histograms of SAPS velocities for different Dst bins and MLAT-MLT locations are presented. We find significant differences in SAPS characteristics between periods of low and high geomagnetic activity, suggesting that SAPS are driven by different mechanisms during storm and non-storm conditions. To further explore this possibility, we have characterized the SAPS location and peak speed relative to the ionospheric trough specified by GPS Total Electron Content (TEC) data from the MIT Haystack Madrigal database. A particular emphasis is placed on identifying the extent to which the location, structure, and depth of the trough may play a controlling influence on SAPS speeds during storm and non-storm periods. The results are interpreted in terms of the current paradigm for active thermosphere-ionosphere feedback being an important component of SAPS physics.
VizieR Online Data Catalog: NLTE spectral analysis of white dwarf G191-B2B (Rauch+, 2013)

NASA Astrophysics Data System (ADS)

Rauch, T.; Werner, K.; Bohlin, R.; Kruk, J. W.

2013-08-01

In the framework of the Virtual Observatory, the German Astrophysical Virtual Observatory developed the registered service TheoSSA. It provides easy access to stellar spectral energy distributions (SEDs) and is intended to ingest SEDs calculated by any model-atmosphere code. In case of the DA white dwarf G191-B2B, we demonstrate that the model reproduces not only its overall continuum shape but also the numerous metal lines exhibited in its ultraviolet spectrum. (3 data files).
SEDs at Los Alamos: A Personal Memoir

NASA Astrophysics Data System (ADS)

Bederson, Benjamin

2001-03-01

I have written this personal memoir approximately 55 years after the events I describe. It is based almost exclusively on memory, since apart from the diary I kept while on Tinian, I have few documents concerning it. It covers my service in the U.S. Army's Special Engineering Detachment (SED) in Oak Ridge and Los Alamos in 1944-45, on Tinian island, the launching pad for the bombing raids on Japan, in the summer and fall of 1945, and my return to Los Alamos until my discharge in January 1946.
What Sets the Radial Locations of Warm Debris Disks?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ballering, Nicholas P.; Rieke, George H.; Su, Kate Y. L.

The architectures of debris disks encode the history of planet formation in these systems. Studies of debris disks via their spectral energy distributions (SEDs) have found infrared excesses arising from cold dust, warm dust, or a combination of the two. The cold outer belts of many systems have been imaged, facilitating their study in great detail. Far less is known about the warm components, including the origin of the dust. The regularity of the disk temperatures indicates an underlying structure that may be linked to the water snow line. If the dust is generated from collisions in an exo-asteroid belt,more » the dust will likely trace the location of the water snow line in the primordial protoplanetary disk where planetesimal growth was enhanced. If instead the warm dust arises from the inward transport from a reservoir of icy material farther out in the system, the dust location is expected to be set by the current snow line. We analyze the SEDs of a large sample of debris disks with warm components. We find that warm components in single-component systems (those without detectable cold components) follow the primordial snow line rather than the current snow line, so they likely arise from exo-asteroid belts. While the locations of many warm components in two-component systems are also consistent with the primordial snow line, there is more diversity among these systems, suggesting additional effects play a role.« less
Validity of two wearable monitors to estimate breaks from sedentary time

PubMed Central

Lyden, Kate; Kozey-Keadle, Sarah L.; Staudenmayer, John W.; Freedson, Patty S.

2012-01-01

Investigations employing wearable monitors have begun to examine how sedentary time behaviors influence health. Purpose To demonstrate the utility of a measure of sedentary behavior and to validate the activPAL and ActiGraph GT3X for estimating measures of sedentary behavior: absolute number of breaks and break-rate. Methods Thirteen participants completed two, 10-hour conditions. During the baseline condition, participants performed normal daily activity and during the treatment condition, participants were asked to reduce and break-up their sedentary time. In each condition, participants wore two ActiGraph GT3X monitors and one activPAL. The ActiGraph was tested using the low frequency extension filter (AG-LFE) and the normal filter (AG-Norm). For both ActiGraph monitors two count cut-points to estimate sedentary time were examined: 100 and 150 counts∙min−1. Direct observation served as the criterion measure of total sedentary time, absolute number of breaks from sedentary time and break-rate (number of breaks per sedentary hour [brks.sed-hr−1]). Results Break-rate was the only metric sensitive to changes in behavior between baseline (5.1 [3.3 to 6.8] brks.sed-hr−1) and treatment conditions (7.3 [4.7 to 9.8] brks.sed-hr−1) (mean [95% CI]). The activPAL produced valid estimates of all sedentary behavior measures and was sensitive to changes in break-rate between conditions (baseline: 5.1 [2.8 to 7.1] brks.sed-hr−1, treatment: 8.0 [5.8 to 10.2] brks.sed-hr−1). In general, the AG-LFE and AG-Norm were not accurate in estimating break-rate or absolute number of breaks and were not sensitive to changes between conditions. Conclusion This study demonstrates the utility of expressing breaks from sedentary time as a rate per sedentary hour, a metric specifically relevant to free-living behavior, and provides further evidence that the activPAL is a valid tool to measure components of sedentary behavior in free-living environments. PMID:22648343
The simultaneous low state spectral energy distribution of 1ES 2344+514 from radio to very high energies

DOE PAGES

Aleksić, J.; Antonelli, L. A.; Antoranz, P.; ...

2013-07-31

Here, BL Lacertae objects are variable at all energy bands on time scales down to minutes. To construct and interpret their spectral energy distribution (SED), simultaneous broad-band observations are mandatory. Up to now, the number of objects studied during such campaigns is very limited and biased towards high flux states. Furthermore, we present the results of a dedicated multi-wavelength study of the high-frequency peaked BL Lacertae (HBL) object and known TeV emitter 1ES 2344+514 by means of a pre-organised campaign. The observations were conducted during simultaneous visibility windows of MAGIC and AGILE in late 2008. The measurements were complemented bymore » Metsähovi, RATAN-600, KVA+Tuorla, Swift and VLBA pointings. Additional coverage was provided by the ongoing long-term F-GAMMA and MOJAVE programs, the OVRO 40-m and CrAO telescopes as well as the Fermi satellite. The obtained SEDs are modelled using a one-zone as well as a self-consistent two-zone synchrotron self-Compton model. As a result, 1ES 2344+514 was found at very low flux states in both X-rays and very high energy gamma rays. Variability was detected in the low frequency radio and X-ray bands only, where for the latter a small flare was observed. The X-ray flare was possibly caused by shock acceleration characterised by similar cooling and acceleration time scales. MOJAVE VLBA monitoring reveals a static jet whose components are stable over time scales of eleven years, contrary to previous findings. There appears to be no significant correlation between the 15 GHz and R-band monitoring light curves. The observations presented here constitute the first multi-wavelength campaign on 1ES 2344+514 from radio to VHE energies and one of the few simultaneous SEDs during low activity states. The quasi-simultaneous Fermi-LAT data poses some challenges for SED modelling, but in general the SEDs are described well by both applied models. The resulting parameters are typical for TeV emitting HBLs. Consequently it remains unclear whether a so-called quiescent state was found in this campaign.« less

Effects of creatine supplementation associated with resistance training on oxidative stress in different tissues of rats

PubMed Central

2014-01-01

Background Creatine supplementation is known to exert an effect by increasing strength in high intensity and short duration exercises. There is a hypothesis which suggests that creatine supplementation may provide antioxidant activity by scavenging Reactive Oxygen Species. However, the antioxidant effect of creatine supplementation associated with resistance training has not yet been described in the literature. Therefore, we investigated the effect of creatine monohydrate supplementation associated with resistance training over maximum strength gain and oxidative stress in rats. Methods Forty male Wistar rats (250-300 g, 90 days old) were randomly allocated into 4 groups: Sedentary (SED, n = 10), Sedentary + Creatine (SED-Cr, n = 10), Resistance Training (RT, n = 10) and Resistance Training + Creatine (RT-Cr, n = 10). Trained animals were submitted to the RT protocol (4 series of 10–12 repetitions, 90 second interval, 4 times per week, 65% to 75% of 1MR, for 8 weeks). Results In this study, greater strength gain was observed in the SED-Cr, RT and RT-Cr groups compared to the SED group (P < 0.001). The RT-Cr group showed a higher maximum strength gain when compared to other groups (P < 0.001). Creatine supplementation associated with resistance training was able to reduce lipoperoxidation in the plasma (P < 0.05), the heart (P < 0.05), the liver (P < 0.05) and the gastrocnemius (P < 0.05) when compared to control groups. However, the supplementation had no influence on catalase activity (CAT) in the analyzed organs. Only in the heart was the CAT activity higher in the RT-Cr group (P < 0.05). The activity of superoxide dismutase (SOD) was lower in all of the analyzed organs in the SED-Cr group (P < 0.05), while SOD activity was lower in the trained group and sedentary supplemented group (P < 0.05). Conclusions Creatine was shown to be an effective non-enzymatic antioxidant with supplementation alone and also when it was associated with resistance training in rats. PMID:24655435
Relationship between Aortic Compliance and Impact of Cerebral Blood Flow Fluctuation to Dynamic Orthostatic Challenge in Endurance Athletes.

PubMed

Tomoto, Tsubasa; Imai, Tomoko; Ogoh, Shigehiko; Maeda, Seiji; Sugawara, Jun

2018-01-01

Aorta effectively buffers cardiac pulsatile fluctuation generated from the left ventricular (LV) which could be a mechanical force to high blood flow and low-resistance end-organs such as the brain. A dynamic orthostatic challenge may evoke substantial cardiac pulsatile fluctuation via the transient increases in venous return and stroke volume (SV). Particularly, this response may be greater in endurance-trained athletes (ET) who exhibit LV eccentric remodeling. The aim of this study was to determine the contribution of aortic compliance to the response of cerebral blood flow fluctuation to dynamic orthostatic challenge in ET and age-matched sedentary (SED) young healthy men. ET ( n = 10) and SED ( n = 10) underwent lower body negative pressure (LBNP) (-30 mmHg for 4 min) stimulation and release the pressure that initiates a rapid regain of limited venous return and consequent increase in SV. The recovery responses of central and middle cerebral arterial (MCA) hemodynamics from the release of LBNP (~15 s) were evaluated. SV (via Modeflow method) and pulsatile and systolic MCA (via transcranial Doppler) normalized by mean MCA velocity (MCAv) significantly increased after the cessation of LBNP in both groups. ET exhibited the higher ratio of SV to aortic pulse pressure (SV/ Ao PP), an index of aortic compliance, at the baseline compared with SED ( P < 0.01). Following the LBNP release, SV was significantly increased in SED by 14 ± 7% (mean ± SD) and more in ET by 30 ± 15%; nevertheless, normalized pulsatile, systolic, and diastolic MCAv remained constant in both groups. These results might be attributed to the concomitant with the increase in aortic compliance assessed by SV/ Ao PP. Importantly, the increase in SV/ Ao PP following the LBNP release was greater in ET than in SED ( P < 0.01), and significantly correlated with the baseline SV/ Ao PP ( r = 0.636, P < 0.01). These results suggest that the aortic compliance in the endurance athletes is able to accommodate the additional SV and buffer the potential increase in pulsatility at end-organs such as the brain.
dSED: A database tool for modeling sediment early diagenesis

NASA Astrophysics Data System (ADS)

Katsev, S.; Rancourt, D. G.; L'Heureux, I.

2003-04-01

Sediment early diagenesis reaction transport models (RTMs) are becoming powerful tools in providing kinetic descriptions of the metal and nutrient diagenetic cycling in marine, lacustrine, estuarine, and other aquatic sediments, as well as of exchanges with the water column. Whereas there exist several good database/program combinations for thermodynamic equilibrium calculations in aqueous systems, at present there exist no database tools for classification and analysis of the kinetic data essential to RTM development. We present a database tool that is intended to serve as an online resource for information about chemical reactions, solid phase and solute reactants, sorption reactions, transport mechanisms, and kinetic and equilibrium parameters that are relevant to sediment diagenesis processes. The list of reactive substances includes but is not limited to organic matter, Fe and Mn oxides and oxyhydroxides, sulfides and sulfates, calcium, iron, and manganese carbonates, phosphorus-bearing minerals, and silicates. Aqueous phases include dissolved carbon dioxide, oxygen, methane, hydrogen sulfide, sulfate, nitrate, phosphate, some organic compounds, and dissolved metal species. A number of filters allow extracting information according to user-specified criteria, e.g., about a class of substances contributing to the cycling of iron. The database also includes bibliographic information about published diagenetic models and the reactions and processes that they consider. At the time of preparing this abstract, dSED contained 128 reactions and 12 pre-defined filters. dSED is maintained by the Lake Sediment Structure and Evolution (LSSE) group at the University of Ottawa (www.science.uottawa.ca/LSSE/dSED) and we invite input from the geochemical community.
Data-driven, Interpretable Photometric Redshifts Trained on Heterogeneous and Unrepresentative Data

NASA Astrophysics Data System (ADS)

Leistedt, Boris; Hogg, David W.

2017-03-01

We present a new method for inferring photometric redshifts in deep galaxy and quasar surveys, based on a data-driven model of latent spectral energy distributions (SEDs) and a physical model of photometric fluxes as a function of redshift. This conceptually novel approach combines the advantages of both machine learning methods and template fitting methods by building template SEDs directly from the spectroscopic training data. This is made computationally tractable with Gaussian processes operating in flux-redshift space, encoding the physics of redshifts and the projection of galaxy SEDs onto photometric bandpasses. This method alleviates the need to acquire representative training data or to construct detailed galaxy SED models; it requires only that the photometric bandpasses and calibrations be known or have parameterized unknowns. The training data can consist of a combination of spectroscopic and deep many-band photometric data with reliable redshifts, which do not need to entirely spatially overlap with the target survey of interest or even involve the same photometric bands. We showcase the method on the I-magnitude-selected, spectroscopically confirmed galaxies in the COSMOS field. The model is trained on the deepest bands (from SUBARU and HST) and photometric redshifts are derived using the shallower SDSS optical bands only. We demonstrate that we obtain accurate redshift point estimates and probability distributions despite the training and target sets having very different redshift distributions, noise properties, and even photometric bands. Our model can also be used to predict missing photometric fluxes or to simulate populations of galaxies with realistic fluxes and redshifts, for example.
Detailed modelling of a large sample of Herschel sources in the Lockman Hole: identification of cold dust and of lensing candidates through their anomalous SEDs★

NASA Astrophysics Data System (ADS)

Rowan-Robinson, Michael; Wang, Lingyu; Wardlow, Julie; Farrah, Duncan; Oliver, Seb; Bock, Jamie; Clarke, Charlotte; Clements, David; Ibar, Edo; Gonzalez-Solares, Eduardo; Marchetti, Lucia; Scott, Douglas; Smith, Anthony; Vaccari, Mattia; Valtchanov, Ivan

2014-12-01

We have studied in detail a sample of 967 SPIRE sources with 5σ detections at 350 and 500 μm and associations with Spitzer-SWIRE 24 μm galaxies in the HerMES-Lockman survey area, fitting their mid- and far-infrared, and submillimetre, spectral energy distributions (SEDs) in an automatic search with a set of six infrared templates. For almost 300 galaxies, we have modelled their SEDs individually to ensure the physicality of the fits. We confirm the need for the new cool and cold cirrus templates, and also of the young starburst template, introduced in earlier work. We also identify 109 lensing candidates via their anomalous SEDs and provide a set of colour-redshift constraints which allow lensing candidates to be identified from combined Herschel and Spitzer data. The picture that emerges of the submillimetre galaxy population is complex, comprising ultraluminous and hyperluminous starbursts, lower luminosity galaxies dominated by interstellar dust emission, lensed galaxies and galaxies with surprisingly cold (10-13 K) dust. 11 per cent of 500 μm selected sources are lensing candidates. 70 per cent of the unlensed sources are ultraluminous infrared galaxies and 26 per cent are hyperluminous. 34 per cent are dominated by optically thin interstellar dust (`cirrus') emission, but most of these are due to cooler dust than is characteristic of our Galaxy. At the highest infrared luminosities we see SEDs dominated by M82, Arp 220 and young starburst types, in roughly equal proportions.
Exercise sensitizes skeletal muscle to extracellular ATP for IL-6 expression in mice.

PubMed

Fernández-Verdejo, R; Casas, M; Galgani, J E; Jaimovich, E; Buvinic, S

2014-04-01

Active skeletal muscle synthesizes and releases interleukin-6 (IL-6), which plays important roles in the organism's adaptation to exercise. Autocrine/paracrine ATP signaling has been shown to modulate IL-6 expression. The aim of this study was to determine whether a period of physical activity modifies the ATP-induced IL-6 expression. BalbC mice were either subject to 5 weeks voluntary wheel running (VA) or kept sedentary (SED). Flexor digitorum brevis muscles were dissected, stimulated with different ATP concentrations (0-100 μM) and IL-6 mRNA levels were measured using qPCR. ATP evoked a concentration-dependent rise in IL-6 mRNA in both SED and VA mice. VA mice however, had significantly higher ATP sensitivity (pD2 pharmacological values: VA=5.58±0.02 vs. SED=4.95±0.04, p<0.05). Interestingly, in VA mice we observed a positive correlation between the level of physical activity and the IL-6 mRNA increase following fiber stimulation with 10 μM ATP. In addition, there were lower P2Y2- and higher P2Y14-receptor mRNA levels in skeletal muscles of VA compared to SED mice, showing plasticity of nucleotide receptors with exercise. These results suggest that exercise increases skeletal muscle ATP sensitivity, a response dependent on the level of physical activity performed. This could have an important role in the mechanisms controlling skeletal muscle adaptation to exercise and training. © Georg Thieme Verlag KG Stuttgart · New York.
γ-Ray And Parsec-Scale Jet Properties Of A Complete Sample Of Blazars From The Mojave Program

DOE PAGES

Lister, M. L.

2011-11-02

We investigate the Fermi LAT -ray and 15 GHz VLBA radio properties of a joint -ray- and radio-selected sample of AGNs obtained during the first 11 months of the Fermi mission (2008 Aug 4 - 2009 Jul 5). Our sample contains the brightest 173 AGNs in these bands above declination -30° during this period, and thus probes the full range of -ray loudness ( -ray to radio band luminosity ratio) in the bright blazar population. The latter quantity spans at least four orders ofmagnitude, reflecting a wide range of spectral energy distribution (SED) parameters in the bright blazar population. Themore » BL Lac objects, however, display a linear correlation of increasing -ray loudness with synchrotron SED peak frequency, suggesting a universal SED shape for objects of this class. The synchrotron self-Compton model is favored for the -ray emission in these BL Lacs over external seed photon models, since the latter predict a dependence of Compton dominance on Doppler factor that would destroy any observed synchrotron SED peak - -ray loudness correlation. The high-synchrotron peaked (HSP) BL Lac objects are distinguished by lower than average radio core brightness temperatures, and none display large radio modulation indices or high linear core polarization levels. No equivalent trends are seen for the flat-spectrum radio quasars (FSRQ) in our sample. Given the association of such properties with relativistic beaming, we suggest that the HSP BL Lacs have generally lower Doppler factors than the lower-synchrotron peaked BL Lacs or FSRQs in our sample.« less
Spectral Classification of Galaxies at 0.5 <= z <= 1 in the CDFS: The Artificial Neural Network Approach

NASA Astrophysics Data System (ADS)

Teimoorinia, H.

2012-12-01

The aim of this work is to combine spectral energy distribution (SED) fitting with artificial neural network techniques to assign spectral characteristics to a sample of galaxies at 0.5 < z < 1. The sample is selected from the spectroscopic campaign of the ESO/GOODS-South field, with 142 sources having photometric data from the GOODS-MUSIC catalog covering bands between ~0.4 and 24 μm in 10-13 filters. We use the CIGALE code to fit photometric data to Maraston's synthesis spectra to derive mass, specific star formation rate, and age, as well as the best SED of the galaxies. We use the spectral models presented by Kinney et al. as targets in the wavelength interval ~1200-7500 Å. Then a series of neural networks are trained, with average performance ~90%, to classify the best SED in a supervised manner. We consider the effects of the prominent features of the best SED on the performance of the trained networks and also test networks on the galaxy spectra of Coleman et al., which have a lower resolution than the target models. In this way, we conclude that the trained networks take into account all the features of the spectra simultaneously. Using the method, 105 out of 142 galaxies of the sample are classified with high significance. The locus of the classified galaxies in the three graphs of the physical parameters of mass, age, and specific star formation rate appears consistent with the morphological characteristics of the galaxies.
The Intrinsic Far-infrared Continua of Type-1 Quasars

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lyu, Jianwei; Rieke, George H., E-mail: jianwei@email.arizona.edu

2017-06-01

The range of currently proposed active galactic nucleus (AGN) far-infrared templates results in uncertainties in retrieving host galaxy information from infrared observations and also undermines constraints on the outer part of the AGN torus. We discuss how to test and reconcile these templates. Physically, the fraction of the intrinsic AGN IR-processed luminosity compared with that from the central engine should be consistent with the dust-covering factor. In addition, besides reproducing the composite spectral energy distributions (SEDs) of quasars, a correct AGN IR template combined with an accurate library of star-forming galaxy templates should be able to reproduce the IR propertiesmore » of the host galaxies, such as the luminosity-dependent SED shapes and aromatic feature strengths. We develop tests based on these expected behaviors and find that the shape of the AGN intrinsic far-IR emission drops off rapidly starting at ∼20 μ m and can be matched by an Elvis et al.-like template with a minor modification. Despite the variations in the near- to mid-IR bands, AGNs in quasars and Seyfert galaxies have remarkably similar intrinsic far-IR SEDs at λ ∼ 20–100 μ m, suggesting a similar emission character of the outermost region of the circumnuclear torus. The variations of the intrinsic AGN IR SEDs among the type-1 quasar population can be explained by the changing relative strengths of four major dust components with similar characteristic temperatures, and there is evidence for compact AGN-heated dusty structures at sub-kiloparsec scales in the far-IR.« less
SPECTRAL CLASSIFICATION OF GALAXIES AT 0.5 {<=} z {<=} 1 IN THE CDFS: THE ARTIFICIAL NEURAL NETWORK APPROACH

DOE Office of Scientific and Technical Information (OSTI.GOV)

Teimoorinia, H., E-mail: hteimoo@uvic.ca

2012-12-01

The aim of this work is to combine spectral energy distribution (SED) fitting with artificial neural network techniques to assign spectral characteristics to a sample of galaxies at 0.5 < z < 1. The sample is selected from the spectroscopic campaign of the ESO/GOODS-South field, with 142 sources having photometric data from the GOODS-MUSIC catalog covering bands between {approx}0.4 and 24 {mu}m in 10-13 filters. We use the CIGALE code to fit photometric data to Maraston's synthesis spectra to derive mass, specific star formation rate, and age, as well as the best SED of the galaxies. We use the spectralmore » models presented by Kinney et al. as targets in the wavelength interval {approx}1200-7500 A. Then a series of neural networks are trained, with average performance {approx}90%, to classify the best SED in a supervised manner. We consider the effects of the prominent features of the best SED on the performance of the trained networks and also test networks on the galaxy spectra of Coleman et al., which have a lower resolution than the target models. In this way, we conclude that the trained networks take into account all the features of the spectra simultaneously. Using the method, 105 out of 142 galaxies of the sample are classified with high significance. The locus of the classified galaxies in the three graphs of the physical parameters of mass, age, and specific star formation rate appears consistent with the morphological characteristics of the galaxies.« less
Gamma-Ray and Parsec-Scale Jet Properties of a Complete Sample of Blazars from the MOJAVE Program

NASA Technical Reports Server (NTRS)

Lister, M.L.; Aller, M.; Aller, H.; Hovatta, T.; Kellermann, K. I.; Kovalev, Y. Y.; Meyer, E. T.; Pushkarev, A. B.; Ros, E.; Ackermann, M.;

2011-01-01

We investigate the Fermi LAT gamma-ray and 15 GHz VLBA radio properties of a joint gamma-ray- and radio-selected sample of AGNs obtained during the first 11 months of the Fermi mission (2008 Aug 4 - 2009 Jul 5). Our sample contains the brightest 173 AGNs in these bands above declination -300 during this period, and thus probes the full range of gamma-ray loudness (gamma-ray to radio band luminosity ratio) in the bright blazar population. The latter quantity spans at least four orders of magnitude, reflecting a wide range of spectral energy distribution (SED) parameters in the bright blazar population. The BL Lac objects, however, display a linear correlation of increasing gamma-ray loudness with synchrotron SED peak frequency, suggesting a universal SED shape for objects of this class. The synchrotron self-Compton model is favored for the gamma-ray emission in these BL Lacs over external seed photon models, since the latter predict a dependence of Compton dominance on Doppler factor that would destroy any observed synchrotron SED peak - gamma-ray loudness correlation. The high-synchrotron peaked (HSP) BL Lac objects are distinguished by lower than average radio core brightness temperatures, and none display large radio modulation indices or high linear core polarization levels. No equivalent trends are seen for the flat-spectrum radio quasars (FSRQ) in our sample. Given the association of such properties with relativistic beaming, we suggest that the HSP BL Lacs have generally lower Doppler factors than the lower-synchrotron peaked BL Lacs or FSRQs in our sample.

Detection of classical enterotoxins and identification of enterotoxin genes in Staphylococcus aureus from milk and dairy products.

PubMed

Morandi, S; Brasca, M; Lodi, R; Cremonesi, P; Castiglioni, B

2007-09-20

Milk and dairy products are frequently contaminated with enterotoxigenic Staphylococcus aureus, which is often involved in staphylococcal food poisoning. The distribution of genes encoding staphylococcal enterotoxins (SE) in S. aureus isolated from bovine, goat, sheep and buffalo milk and dairy products was verified by the presence of the corresponding SE production. A total of 112 strains of S. aureus were tested for SE production by immuno-enzymatic (SEA-SEE) and reversed passive latex agglutination (SEA-SED) methods, while multiplex-PCR was applied for SE genes (sea, sec, sed, seg, seh, sei, sej and sel). Of the total strains studied, 67% were detected to have some SE genes (se), but only 52% produced a detectable amount of the classic antigenic SE types. The bovine isolates frequently had enterotoxin SEA, SED and sej, while SEC and sel predominated in the goat and sheep strains. The results demonstrated (i) marked enterotoxigenic S. aureus strain variations, in accordance with strain origin and (ii) the two methods resulted in different information but concurred on the risk of foodstuff infection by S. aureus.
Radiative feedback and cosmic molecular gas: the role of different radiative sources

NASA Astrophysics Data System (ADS)

Maio, Umberto; Petkova, Margarita; De Lucia, Gabriella; Borgani, Stefano

2016-08-01

We present results from multifrequency radiative hydrodynamical chemistry simulations addressing primordial star formation and related stellar feedback from various populations of stars, stellar spectral energy distributions (SEDs) and initial mass functions. Spectra for massive stars, intermediate-mass stars and regular solar-like stars are adopted over a grid of 150 frequency bins and consistently coupled with hydrodynamics, heavy-element pollution and non-equilibrium species calculations. Powerful massive Population III stars are found to be able to largely ionize H and, subsequently, He and He+, causing an inversion of the equation of state and a boost of the Jeans masses in the early intergalactic medium. Radiative effects on star formation rates are between a factor of a few and 1 dex, depending on the SED. Radiative processes are responsible for gas heating and photoevaporation, although emission from soft SEDs has minor impacts. These findings have implications for cosmic gas preheating, primordial direct-collapse black holes, the build-up of `cosmic fossils' such as low-mass dwarf galaxies, the role of active galactic nuclei during reionization, the early formation of extended discs and angular-momentum catastrophe.
SedFoam-2.0: a 3-D two-phase flow numerical model for sediment transport

NASA Astrophysics Data System (ADS)

Chauchat, Julien; Cheng, Zhen; Nagel, Tim; Bonamy, Cyrille; Hsu, Tian-Jian

2017-11-01

In this paper, a three-dimensional two-phase flow solver, SedFoam-2.0, is presented for sediment transport applications. The solver is extended from twoPhaseEulerFoam available in the 2.1.0 release of the open-source CFD (computational fluid dynamics) toolbox OpenFOAM. In this approach the sediment phase is modeled as a continuum, and constitutive laws have to be prescribed for the sediment stresses. In the proposed solver, two different intergranular stress models are implemented: the kinetic theory of granular flows and the dense granular flow rheology μ(I). For the fluid stress, laminar or turbulent flow regimes can be simulated and three different turbulence models are available for sediment transport: a simple mixing length model (one-dimensional configuration only), a k - ɛ, and a k - ω model. The numerical implementation is demonstrated on four test cases: sedimentation of suspended particles, laminar bed load, sheet flow, and scour at an apron. These test cases illustrate the capabilities of SedFoam-2.0 to deal with complex turbulent sediment transport problems with different combinations of intergranular stress and turbulence models.
Estimation of skin entrance doses (SEDs) for common medical X-ray diagnostic examinations in India and proposed diagnostic reference levels (DRLs).

PubMed

Sonawane, A U; Shirva, V K; Pradhan, A S

2010-02-01

Skin entrance doses (SEDs) were estimated by carrying out measurements of air kerma from 101 X-ray machines installed in 45 major and selected hospitals in the country by using a silicon detector-based dose Test-O-Meter. 1209 number of air kerma measurements of diagnostic projections for adults have been analysed for seven types of common diagnostic examinations, viz. chest (AP, PA, LAT), lumbar spine (AP, LAT), thoracic spine (AP, LAT), abdomen (AP), pelvis (AP), hip joints (AP) and skull (PA, LAT) for different film-screen combinations. The values of estimated diagnostic reference levels (DRLs) (third quartile values of SEDs) were compared with guidance levels/DRLs of doses published by the IAEA-BSS-Safety Series No. 115, 1996; HPA (NRPB) (2000 and 2005), UK; CRCPD/CDRH (USA), European Commission and other national values. The values of DRLs obtained in this study are comparable with the values published by the IAEA-BSS-115 (1996); HPA (NRPB) (2000 and 2005) UK; EC and CRCPD/CDRH, USA including values obtained in previous studies in India.
Low-luminosity Blazars in Wise: A Mid-infrared View of Unification

NASA Astrophysics Data System (ADS)

Plotkin, Richard M.; Anderson, S. F.; Brandt, W. N.; Markoff, S.; Shemmer, O.; Wu, J.

2012-01-01

We use the preliminary data release from the Wide-Field Infrared Survey Explorer (WISE) to perform the first statistical study on the mid-infrared (IR) properties of a large number ( 102) of BL Lac objects -- low-luminosity Active Galactic Nuclei (AGN) with a jet beamed toward the Earth. As expected, many BL Lac objects are so highly beamed that their jet synchrotron emission dominates their IR spectral energy distributions (SEDs), and the shape of their SEDs in the IR correlates well with SED peak frequency. In other BL Lac objects, the jet is not strong enough to completely dilute the rest of the AGN, and we do not see observational signatures of the dusty torus from these weakly beamed BL Lac objects. While at odds with simple unification, the missing torus is consistent with recent suggestions that BL Lac objects are fed by radiatively inefficient accretion flows. We discuss implications on the ``nature vs. nurture" debate for FR I and FR II galaxies, and also on the standard orientation-based AGN unification model.
What the UV SED Tells us About Stellar Populations and Galaxies

NASA Technical Reports Server (NTRS)

Heap, Sara R.

2011-01-01

The UV SED parameter b as in f(sub 1) 1(sup b), is commonly used to estimate fundamental properties of high-redshift galaxies including age and metallicity. However, sources and processes other than age and metallicity can influence the value of b. We use the local starforming dwarf galaxy, I Zw 18, in a case study to investigate uncertainties in age and metallicity inferred from b due errors or uncertainties in: mode of star formation (instantaneous starburst vs. continuous SF), dust extinction, nebular continuous emission (2-photon emission, Balmer continuum flux), and presence of older stars.
Sensitivity Analysis of ProSEDS (Propulsive Small Expendable Deployer System) Data Communication System

NASA Technical Reports Server (NTRS)

Park, Nohpill; Reagan, Shawn; Franks, Greg; Jones, William G.

1999-01-01

This paper discusses analytical approaches to evaluating performance of Spacecraft On-Board Computing systems, thereby ultimately achieving a reliable spacecraft data communications systems. The sensitivity analysis approach of memory system on the ProSEDS (Propulsive Small Expendable Deployer System) as a part of its data communication system will be investigated. Also, general issues and possible approaches to reliable Spacecraft On-Board Interconnection Network and Processor Array will be shown. The performance issues of a spacecraft on-board computing systems such as sensitivity, throughput, delay and reliability will be introduced and discussed.
Effects of Continuous and Accumulated Exercise on Endothelial Function in Rat Aorta.

PubMed

Martinez, Juliana Edwiges; Taipeiro, Elane de Fátima; Chies, Agnaldo Bruno

2017-04-01

The practice of exercise in short bouts repeated throughout the day may be an alternative strategy to lift people out of physical inactivity. to evaluate if accumulated exercise, as occurs in continuous exercise training, improve endothelial function in rat aorta. Wistar male rats were divided into three groups: continuous exercise (CEx, 1 hour on the treadmill) or accumulated exercise (AEx, 4 bouts of 15 minutes / day) for 5 days/week for 8 weeks, or sedentary (SED). During the training period, body weight gain and increase in exercise performance were recorded. On sacrifice day, aorta was dissected into rings (3-5 mm) and mounted on the organ bath. Fitness was significantly greater in CEx and AEx rats as compared with SED animals. In addition, compared with the SED group, CEx animals had a lower body mass gain, and the aorta obtained from these animals had reduced contractile response to norepinephrine and greater acetylcholine-induced relaxation. These results were not observed in ACEx animals. Both CEx and AEx improved fitness, but only CEx led to reduced body weight gain and improved endothelial function. A prática de exercícios em sessões curtas que se repetem ao longo do dia pode ser uma alternativa para tirar as pessoas da inatividade física. Verificar se o exercício acumulado, tal como ocorre com o treinamento com exercício contínuo, melhora a função endotelial na aorta de ratos. Ratos Wistar machos foram divididos em 3 grupos: treinamento com exercício contínuo (ExC; 1 hora em esteira) ou com exercício acumulado (ExA; 4 sessões de 15 minutos ao longo do dia) por 5 dias/semana, durante 8 semanas, ou grupo sedentário (SED). Durante o treinamento, foram registrados o ganho de peso corporal e desempenho na esteira. No dia do sacrifício, anéis (3-5 mm) da aorta foram obtidos e montados em banho de órgãos. Animais ExC e ExA mostraram aptidão física significativamente maior em comparação com os SED. Paralelamente, em comparação com SED, animais ExC tiveram menor ganho de massa corporal, e aortas retiradas desses animais mostraram respostas contrácteis à noradrenalina reduzidas e maior relaxamento induzido pela acetilcolina. Esses resultados não foram observados no grupo ExA. Tanto o ExC quanto o ExA melhoraram a aptidão física, mas somente o ExC foi capaz de reduzir o ganho de peso corporal dos animais e melhorar a função endotelial.
The virtual observatory service TheoSSA: Establishing a database of synthetic stellar flux standards. I. NLTE spectral analysis of the DA-type white dwarf G191-B2B

NASA Astrophysics Data System (ADS)

Rauch, T.; Werner, K.; Bohlin, R.; Kruk, J. W.

2013-12-01

Context. Hydrogen-rich, DA-type white dwarfs are particularly suited as primary standard stars for flux calibration. State-of-the-art NLTE models consider opacities of species up to trans-iron elements and provide reliable synthetic stellar-atmosphere spectra to compare with observations. Aims: We will establish a database of theoretical spectra of stellar flux standards that are easily accessible via a web interface. Methods: In the framework of the Virtual Observatory, the German Astrophysical Virtual Observatory developed the registered service TheoSSA. It provides easy access to stellar spectral energy distributions (SEDs) and is intended to ingest SEDs calculated by any model-atmosphere code. In case of the DA white dwarf G191-B2B, we demonstrate that the model reproduces not only its overall continuum shape but also the numerous metal lines exhibited in its ultraviolet spectrum. Results: TheoSSA is in operation and contains presently a variety of SEDs for DA-type white dwarfs. It will be extended in the near future and can host SEDs of all primary and secondary flux standards. The spectral analysis of G191-B2B has shown that our hydrostatic models reproduce the observations best at and log g = 7.60 ± 0.05. We newly identified Fe vi, Ni vi, and Zn iv lines. For the first time, we determined the photospheric zinc abundance with a logarithmic mass fraction of -4.89 (7.5 × solar). The abundances of He (upper limit), C, N, O, Al, Si, O, P, S, Fe, Ni, Ge, and Sn were precisely determined. Upper abundance limits of about 10% solar were derived for Ti, Cr, Mn, and Co. Conclusions: The TheoSSA database of theoretical SEDs of stellar flux standards guarantees that the flux calibration of all astronomical data and cross-calibration between different instruments can be based on the same models and SEDs calculated with different model-atmosphere codes and are easy to compare. Based on observations with the NASA/ESA Hubble Space Telescope, obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS5-26666.Based on observations made with the NASA-CNES-CSA Far Ultraviolet Spectroscopic Explorer.Figures 1, 6, 10-12, 23, A.1, A.2 and Tables 2-4 are available in electronic form at http://www.aanda.orgTable 5 and Figs. A.1 and A.2 (FITS files) are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/560/A106

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