Chemical characterization, antioxidant and antimicrobial activity of propolis obtained from Melipona quadrifasciata quadrifasciata and Tetragonisca angustula stingless bees.

PubMed

Torres, A R; Sandjo, L P; Friedemann, M T; Tomazzoli, M M; Maraschin, M; Mello, C F; Santos, A R S

2018-01-01

In this study, we investigated the chemical composition, and antioxidant and antibacterial properties of ethanolic extracts of propolis (EEP) from Melipona quadrifasciata quadrifasciata and Tetragonisca angustula. Chemical composition of EEP was determined by colorimetry and chromatographic (HPLC-DAD and UPLC-Q/TOF-MS/MS) analysis. Antimicrobial activity of EEP was evaluated against gram-positive (S. aureus, methicillin-resistant S. aureus, E. faecalis) and gram-negative (E. coli and K. pneumoniae) bacteria by the minimal inhibitory concentration (MIC) test using the microdilution method. Furthermore, the growth curve and integrity of cell membrane of S. aureus and E. coli were investigated using standard microbiological methods. HPLC-DAD analysis showed that the EEP of M. quadrifasciata quadrifasciata has a more complex chemical composition than the EEP of T. angustula. Moreover, UPLC-MS analyses of M. quadrifasciata quadrifascita indicated flavonoids and terpenes as major constituents. The bactericidal activity of both EEPs was higher against gram-positive bacteria than for gram-negative bacteria. The EEP from M. quadrifasciata quadrifasciata presented MIC values lower than the EEP from T. angustula for all tested bacteria. The EEP from M. quadrifasciata quadrifasciata caused lysis of the bacterial wall and release of intracellular components from both E. coli and S. aureus. Our findings indicate that the chemical composition of propolis from stingless bees is complex and depends on the species. The extract from M. quadrifasciata quadrifascita was more effective against gram-positive than gram-negative strains, especially against S. aureus and methicillin-resistant S. aureus compared to T. angustula extract, by a mechanism that involves disturbance of the bacterial cell membrane integrity.

A model providing long-term data sets of energetic electron precipitation during geomagnetic storms

NASA Astrophysics Data System (ADS)

van de Kamp, M.; Seppälä, A.; Clilverd, M. A.; Rodger, C. J.; Verronen, P. T.; Whittaker, I. C.

2016-10-01

The influence of solar variability on the polar atmosphere and climate due to energetic electron precipitation (EEP) has remained an open question largely due to lack of a long-term EEP forcing data set that could be used in chemistry-climate models. Motivated by this, we have developed a model for 30-1000 keV radiation belt driven EEP. The model is based on precipitation data from low Earth orbiting POES satellites in the period 2002-2012 and empirically described plasmasphere structure, which are both scaled to a geomagnetic index. This geomagnetic index is the only input of the model and can be either Dst or Ap. Because of this, the model can be used to calculate the energy-flux spectrum of precipitating electrons from 1957 (Dst) or 1932 (Ap) onward, with a time resolution of 1 day. Results from the model compare well with EEP observations over the period of 2002-2012. Using the model avoids the challenges found in measured data sets concerning proton contamination. As demonstrated, the model results can be used to produce the first ever >80 year long atmospheric ionization rate data set for radiation belt EEP. The impact of precipitation in this energy range is mainly seen at altitudes 70-110 km. The ionization rate data set, which is available for the scientific community, will enable simulations of EEP impacts on the atmosphere and climate with realistic EEP variability. Due to limitations in this first version of the model, the results most likely represent an underestimation of the total EEP effect.

Electrical potential modulation of dynamic film properties of aqueous surfactant solutions through a nanogap

NASA Astrophysics Data System (ADS)

Xie, Guoxin; Luo, Jianbin; Liu, Shuhai; Guo, Dan

2011-01-01

The effect of external electrical potentials (EEPs) on aqueous surfactant films nanoconfined in a ball-plate configuration has been investigated by measuring the dynamic film thickness with an interferometer. Experimental results indicate that the film formation properties of the surfactant solutions in the nanogap under applied EEPs are strongly dependent on the interfacial adsorbed surfactant structure. Effective control over the film formation properties by applying EEPs depends on the signs of the charges on the solid surface and the surfactant headgroups, the surfactant concentration, and the magnitude of EEPs. Remarkable alterations of the film formation properties in the nanogap by EEPs can be observed except when the surface charge is the same in sign as the headgroups and the surfactant concentration is above the critical micelle concentration. Mechanisms of these phenomena have been discussed in this work.

The impact of an environmental education program on children's and parents' knowledge, attitudes, motivation and behaviors

NASA Astrophysics Data System (ADS)

Legault, Louise M. R.

1999-11-01

Developments in the Quebec educational system enabled us to evaluate the impact of a new educational environmental program (EEP) on a group of children enrolled in this program for the first time (i.e., the experimental group). This EEP comprised a formal curriculum and environmental activities. A control group of children was enrolled in schools where environmental issues were confined to the natural sciences subject. The goals of this study were threefold. The first goal was to evaluate the impact of an EEP on children's and parents' ecological knowledge, attitudes, motivation, and behaviors. The second goal was to investigate if a motivational model of ecological behaviors observed in adult populations could be replicated with children. Part of this goal also included the comparison of path analyses results across experimental conditions, independently for children and parents. The third goal was to identify more clearly what specific children's characteristics influenced parents' ecological attitudes and motivation. Included in this goal was the investigation of possible differences in the strength of associations between constructs in paths analyses conducted in the experimental and control groups of parents. Results suggested that children in the experimental group were more likely to ask teachers and parents for ecological information and presented a more self-determined motivational profile. Additional analyses revealed that children enrolled in an EEP performed ecological behaviors less for extrinsic motives. Level of knowledge, other attitudes and behavioral measures did not differ significantly between the two groups. Parents of children in the experimental group reported lower levels of satisfaction towards the environment and were more likely to get information on ecological issues and strategies from children. No other significant differences between groups of parents were found. Path analyses results suggested that parents' perceptions of children's provision of autonomy support and of ecological information, as well as, joint child/parent involvement in ecological activities favored parents' ecological attitudes and motivation. These results were consistent across the experimental and the control groups. Future studies are necessary to identify optimal intervention strategies devised to foster in people a sense of personal responsibility and self-determination that may propel them into action.

Estimates of Eastern Equatorial Pacific Sea Surface Temperatures During the Pliocene From Carbonate 'Clumped Isotope' Thermometry

NASA Astrophysics Data System (ADS)

Thiagarajan, N.; Tripati, A.; Eiler, J.

2007-12-01

The early Pliocene (5 to 3 Ma) was an interval in Earth history that was globally warmer than the present; thus, study of the details of Pliocene climate can provide insights into the dynamics of warm climates. There are two competing models of the temperature structure of the tropical Pacific upper-ocean during the early Pliocene: the dynamical 'ocean thermostat' model [1,2] and the 'El Padre' (or permanent 'El Nino') model [3], each of which predict zonal temperature gradients and mean conditions in the Eastern Equatorial Pacific (EEP), and which differ markedly from one another in these predictions. The dynamical 'ocean thermostat' model predicts an increased temperature contrast between the Western Equatorial Pacific (WEP) and EEP, enhanced thermocline tilt and intensified upwelling under warmer conditions. In contrast, the 'El Padre' model postulates a collapse of the zonal temperature gradient, reduced thermocline tilt and a reduction in upwelling and/or warmer temperatures of upwelled waters. Existing reconstructions of tropical temperatures produce WEP sea surface temperatures which agree with each other, but yield very different results in the EEP [4,5]. We have reconstructed EEP sea surface temperatures at Ocean Drilling Program (ODP) Site 847 using a few samples spanning key intervals of the last 6 million years using carbonate clumped isotope thermometer [6,7,8]. This technique is based on the temperature dependence of the abundances of 13C-18O bonds in carbonate minerals. Initial measurements of planktonic foraminifera and coccoliths from ODP Site 847 indicate cool EEP sea surface temperatures, supporting models of Pliocene climate that have enhanced zonal temperature gradients, relative to modern. Analyses of Globigerinoides sacculifer (with sac) from sediments indicate calcification temperatures of 20.3°C ± 0.1°C and seawater δ18O values of -0.8‰ ± 0.1‰ from ~6.1 to 5.1 million years ago. Measurements of a mixed coccolith assemblage from the fine fraction of 5.6 Ma sediments show calcification temperatures of 20.4°C ± 2.3°C and seawater δ18O values of -1.4‰ ± 0.6‰. G. sacculifer (with sac) and mixed coccoliths from 1.4 Ma sediments yield calcification temperatures of 22.3°C ± 2.5°C and seawater δ18O values of 1.7‰ ± 0.7‰, and 19.4°C ± 1.8°C and seawater δ18O values of 0.4‰ ± 0.5‰, respectively. Our preliminary findings are consistent with the 'dynamical ocean thermostat' model. [1] Clement, A., et al., 1996, An Ocean Dynamical Thermostat, J. of Clim., 9, 2190-2196. [2] Cane, M., et al., 1997, Twentieth-Century Sea Surface Temperature Trends, Science, 957-960. [3] Fedorov, A., et al., 2006, The Pliocene Paradox (Mechanisms for a permanent El Nino), Science, 312, 1437-1443. [4] Rickaby, R. and Halloran, P., 2005, Cool La Nina during the warmth of the Pliocene?, Science, 307, 1948-1953. [5] Wara, M., et al. ,2005, Permanent El Nino-like conditions during the Pliocene Warm Period, Science, 309, 758-761. [6] Ghosh, P., et al., 2006, 13C-18O bonds in carbonate minerals: A new kind of paleothermometer, GCA, 70, 1439-1456. [7] Eiler, J. and Tripati, A., 2007, 'Clumped isotope' thermometry in benthic foraminifera and ostracods: A novel tool for reconstructing deep-ocean temperatures. Fall AGU. [8] Tripati, A., et al. 2007, 'Carbonate `clumped isotope' thermometry in planktonic foraminifera and coccoliths. Fall AGU.

Synergism between ethanolic extract of propolis (EEP) and anti-tuberculosis drugs on growth of mycobacteria.

PubMed

Scheller, S; Dworniczak, S; Waldemar-Klimmek, K; Rajca, M; Tomczyk, A; Shani, J

1999-01-01

Ethanolic extract of propolis exerts a strong anti-bacterial activity, in addition to antifungal, antiviral and antiprotozoal properties. In previous studies from these laboratories we have demonstrated that the intensity of the bactericidal activity of EEP is correlated with the virulence of the mycobacteria tested, and that EEP has a synergistic effect with antibiotics on growth of staphylococcus aureus. In the present study we investigated whether the same synergism and correlation exists between EEP and some anti-tuberculosis drugs on tuberculosis mycobacteria with different degrees of virulence. Six standard strains and 11 wild strains of mycobacteria were exposed for 30 days to EEP, with or without streptomycin, rifamycin, isoniazid or ethambutol. Out of the 17 strains, 8 were resistant to at least two standard antibiotics, and were considered "multi-resistant strains". The rest were either susceptible or resistant to only one of the antimycobacterial drugs. Antagonism was recorded only in one case, when Staphylococcus aureus were treated with a mixture of EEP and ethambutol, suggesting that a chemical bond could have been formed between this anti-tuberculosis antibiotic and one of the active components of the ethanol extract of propolis.

Anti-Atherogenic Activity of Polyphenol-Rich Extract from Bee Pollen

PubMed Central

Rzepecka-Stojko, Anna; Stojko, Jerzy; Buszman, Ewa

2017-01-01

The aim of this study was to determine the effect of polyphenol-rich ethanol extract of bee pollen (EEP) on atherosclerosis induced by a high-fat diet in ApoE-knockout mice. EEP was given with feed in two doses of 0.1 and 1 g/kg body mass (BM). The studies have been conducted in a period of 16 weeks. The following factors were estimated: total cholesterol (TC), oxidized low density lipoproteins (ox-LDL), asymmetric dimethylarginine (ADMA), angiotensin-converting enzyme (ACE) and angiotensin II (ANG II) in the 5th, 10th, 12th, 14th, and 16th week of the experiment. In the last, i.e., 16th week of the studies the development of coronary artery disease (CAD) was also estimated histopathologically. Supplementing diet with EEP resulted in decreasing TC level. EEP reduced oxidative stress by lowering the levels of ox-LDL, ADMA, ANG II and ACE. EEP protected coronary arteries by significantly limiting the development of atherosclerosis (the dose of 0.1 g/kg BM) or completely preventing its occurrence (the dose of 1 g/kg BM). The obtained results demonstrate that EEP may be useful as a potential anti-atherogenic agent. PMID:29258230

Enhancing Entrepreneurial Self-Efficacy through Vocational Entrepreneurship Education Programmes

ERIC Educational Resources Information Center

Maritz, Alex; Brown, Chris

2013-01-01

The purpose of this study is to report the results of a longitudinal evaluation of a vocational entrepreneurship education programme (EEP) using entrepreneurial self-efficacy (ESE) measures. An empirical, mixed methods longitudinal and effectuation scale was used to measure ESE scores. Results indicate that participation in the programme had a…

Assessment in vitro of cytogenetic and genotoxic effects of propolis on human lymphocytes.

PubMed

Montoro, A; Soriano, J M; Barquinero, J F; Almonacid, M; Montoro, A; Verdú, G; Sahuquillo, V; Villaescusa, J I; Sebastià, N

2012-02-01

We evaluated the genetic damage by ethanolic extract of propolis (EEP) induced to human lymphocytes which were exposed to increasing concentrations (0-2000μgml(-1)). The results indicated that EEP reduced significantly the mitotic index (MI) and proliferation index (PI) when high concentrations of EEP were used. Sister chromatid exchange (SCE) rates indicated that EEP could have genotoxic effects at high concentrations. Exposure of the cells to the amount of ethanol used as solvent did not alter either the MI and cell proliferation kinetics (CPK), or the rate of SCE. The results showed: (a) statistical increase in the percentage the cells with CAs and in the frequency of SCE at the highest concentrations, (b) a decrease in MI and in the CPK values was observed, (c) no effect was noticed in negative controls. In conclusion, it can be assumed that high concentrations of EEP have a cyto and genotoxic effect, in vitro, for human peripheral lymphocytes. Copyright © 2011 Elsevier Ltd. All rights reserved.

The impact of ethanol extract of propolis on biofilm forming by Proteus Mirabilis strains isolated from chronic wounds infections.

PubMed

Kwiecińska-Piróg, Joanna; Skowron, Krzysztof; Śniegowska, Agata; Przekwas, Jana; Balcerek, Maciej; Załuski, Daniel; Gospodarek-Komkowska, Eugenia

2018-05-04

Alcoholic propolis extracts may be used to eliminate microbes in mucous membranes and skin inflammations and in wound infections. The aim of this study was an assessment of the ethanol extract of propolis (EEP) activity against biofilm formation by P. mirabilis. Six clinical strains of P. mirabilis isolated from patients with chronic wound infection, and one reference strain of P. mirabilis ATCC 29906 were used. Biofilm was formed in 96-well plate. In order to evaluate the effect of EEP at a concentration range of 1.56-100 mg/mL on the forming and mature biofilm, P. mirabilis cells were released by sonication. In this study the effectiveness of 25-100 mg/mL of EEP on the forming P. mirabilis biofilm and concentrations of 25-50 mg/mL of EEP on formed biofilm has been demonstrated. Our results suggest the possibility of using the EEP in treatment of chronic wound infection caused by P. mirabilis.

Long-term determination of energetic electron precipitation into the atmosphere from AARDDVARK subionospheric VLF observations

NASA Astrophysics Data System (ADS)

Neal, Jason J.; Rodger, Craig J.; Clilverd, Mark A.; Thomson, Neil R.; Raita, Tero; Ulich, Thomas

2015-03-01

We analyze observations of subionospherically propagating very low frequency (VLF) radio waves to determine outer radiation belt energetic electron precipitation (EEP) flux magnitudes. The radio wave receiver in Sodankylä, Finland (Sodankylä Geophysical Observatory) observes signals from the transmitter with call sign NAA (Cutler, Maine). The receiver is part of the Antarctic-Arctic Radiation-belt Dynamic Deposition VLF Atmospheric Research Konsortia (AARDDVARK). We use a near-continuous data set spanning November 2004 until December 2013 to determine the long time period EEP variations. We determine quiet day curves over the entire period and use these to identify propagation disturbances caused by EEP. Long Wave Propagation Code radio wave propagation modeling is used to estimate the precipitating electron flux magnitudes from the observed amplitude disturbances, allowing for solar cycle changes in the ambient D region and dynamic variations in the EEP energy spectra. Our method performs well during the summer months when the daylit ionosphere is most stable but fails during the winter. From the summer observations, we have obtained 693 days worth of hourly EEP flux magnitudes over the 2004-2013 period. These AARDDVARK-based fluxes agree well with independent satellite precipitation measurements during high-intensity events. However, our method of EEP detection is 10-50 times more sensitive to low flux levels than the satellite measurements. Our EEP variations also show good agreement with the variation in lower band chorus wave powers, providing some confidence that chorus is the primary driver for the outer belt precipitation we are monitoring.

Serratia marcescens Cyclic AMP Receptor Protein Controls Transcription of EepR, a Novel Regulator of Antimicrobial Secondary Metabolites.

PubMed

Stella, Nicholas A; Lahr, Roni M; Brothers, Kimberly M; Kalivoda, Eric J; Hunt, Kristin M; Kwak, Daniel H; Liu, Xinyu; Shanks, Robert M Q

2015-08-01

Serratia marcescens generates secondary metabolites and secreted enzymes, and it causes hospital infections and community-acquired ocular infections. Previous studies identified cyclic AMP (cAMP) receptor protein (CRP) as an indirect inhibitor of antimicrobial secondary metabolites. Here, we identified a putative two-component regulator that suppressed crp mutant phenotypes. Evidence supports that the putative response regulator eepR was directly transcriptionally inhibited by cAMP-CRP. EepR and the putative sensor kinase EepS were necessary for the biosynthesis of secondary metabolites, including prodigiosin- and serratamolide-dependent phenotypes, swarming motility, and hemolysis. Recombinant EepR bound to the prodigiosin and serratamolide promoters in vitro. Together, these data introduce a novel regulator of secondary metabolites that directly connects the broadly conserved metabolism regulator CRP with biosynthetic genes that may contribute to competition with other microbes. This study identifies a new transcription factor that is directly controlled by a broadly conserved transcription factor, CRP. CRP is well studied in its role to help bacteria respond to the amount of nutrients in their environment. The new transcription factor EepR is essential for the bacterium Serratia marcescens to produce two biologically active compounds, prodigiosin and serratamolide. These two compounds are antimicrobial and may allow S. marcescens to compete for limited nutrients with other microorganisms. Results from this study tie together the CRP environmental nutrient sensor with a new regulator of antimicrobial compounds. Beyond microbial ecology, prodigiosin and serratamolide have therapeutic potential; therefore, understanding their regulation is important for both applied and basic science. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

Brain state-dependence of electrically evoked potentials monitored with head-mounted electronics.

PubMed

Richardson, Andrew G; Fetz, Eberhard E

2012-11-01

Inferring changes in brain connectivity is critical to studies of learning-related plasticity and stimulus-induced conditioning of neural circuits. In addition, monitoring spontaneous fluctuations in connectivity can provide insight into information processing during different brain states. Here, we quantified state-dependent connectivity changes throughout the 24-h sleep-wake cycle in freely behaving monkeys. A novel, head-mounted electronic device was used to electrically stimulate at one site and record evoked potentials at other sites. Electrically evoked potentials (EEPs) revealed the connectivity pattern between several cortical sites and the basal forebrain. We quantified state-dependent changes in the EEPs. Cortico-cortical EEP amplitude increased during slow-wave sleep, compared to wakefulness, while basal-cortical EEP amplitude decreased. The results demonstrate the utility of using portable electronics to document state-dependent connectivity changes in freely behaving primates.

In vitro antibacterial effects of glass-ionomer cement containing ethanolic extract of propolis on Streptococcus mutans

PubMed Central

Topcuoglu, Nursen; Ozan, Fatih; Ozyurt, Mustafa; Kulekci, Guven

2012-01-01

Objective: The aim of this study was to evaluate the antibacterial property of glass-ionomer cement (GIC) containing propolis against Streptococcus mutans and its effect on the in vitro S. mutans biofilm formation. Methods: Ethanolic extract of propolis (EEP) was prepared at two concentrations as 25 and 50%. Three different experimental GIC disks were prepared using pure liquid and liquid solutions diluted with 25 and 50 percent of EEP concentrations. Minimum inhibitory concentration (MIC) of EEP on the growth of S. mutans ATCC 25175 was determined by using agar dilution method. Agar diffusion test and an in vitro S. mutans biofilm assay for GIC disks with and without EEP were performed. Results: MIC values of Turkish propolis for S. mutans ATCC 25175 was found as 25 μg/mL. Experimental GICs containing propolis exhibited inhibition zones and their dry biofilm weights were less than the pure GIC. The bacterial density was lower in the GIC containing 50% EEP. Conclusions: A distinct antibacterial and antibiofilm efficacy of propolis containing GIC on S. mutans has been observed. Although further research is needed to show clinical results, antibacterial GIC containing propolis would be a promising material for restoration. PMID:23077424

Lateral geniculate body evoked potentials elicited by visual and electrical stimulation.

PubMed

Choi, Chang Wook; Kim, Pan Sang; Shin, Sun Ae; Yang, Ji Yeon; Yang, Yun Sik

2014-08-01

Blind individuals who have photoreceptor loss are known to perceive phosphenes with electrical stimulation of their remaining retinal ganglion cells. We proposed that implantable lateral geniculate body (LGB) stimulus electrode arrays could be used to generate phosphene vision. We attempted to refine the basic reference of the electrical evoked potentials (EEPs) elicited by microelectrical stimulations of the optic nerve, optic tract and LGB of a domestic pig, and then compared it to visual evoked potentials (VEPs) elicited by short-flash stimuli. For visual function measurement, VEPs in response to short-flash stimuli on the left eye of the domestic pig were assessed over the visual cortex at position Oz with the reference electrode at Fz. After anesthesia, linearly configured platinum wire electrodes were inserted into the optic nerve, optic track and LGB. To determine the optimal stimulus current, EEPs were recorded repeatedly with controlling the pulse and power. The threshold of current and charge density to elicit EEPs at 0.3 ms pulse duration was about ±10 µA. Our experimental results showed that visual cortex activity can be effectively evoked by stimulation of the optic nerve, optic tract and LGB using penetrating electrodes. The latency of P1 was more shortened as the electrical stimulation was closer to LGB. The EEPs of two-channel in the visual cortex demonstrated a similar pattern with stimulation of different spots of the stimulating electrodes. We found that the LGB-stimulated EEP pattern was very similar to the simultaneously generated VEP on the control side, although implicit time deferred. EEPs and VEPs derived from visual-system stimulation were compared. The LGB-stimulated EEP wave demonstrated a similar pattern to the VEP waveform except implicit time, indicating prosthetic-based electrical stimulation of the LGB could be utilized for the blind to perceive vision of phosphenes.

Ethanol-extracted Cameroonian propolis exerts estrogenic effects and alleviates hot flushes in ovariectomized Wistar rats.

PubMed

Zingue, Stéphane; Nde, Chantal Beatrice Magne; Michel, Thomas; Ndinteh, Derek Tantoh; Tchatchou, Jules; Adamou, Moïse; Fernandez, Xavier; Fohouo, Fernand-Nestor Tchuenguem; Clyne, Colin; Njamen, Dieudonné

2017-01-21

Since the biological properties of propolis depend to the plants that can be found in a specific region, propolis from unexplored regions attracts the attention of scientists. Ethanolic extract of Cameroonian propolis (EEP) is used to treat various ailments including gynecological problems and amenorrhea. Since there were no scientific data to support the above claims, the present study was therefore undertaken to assess estrogenic properties of Cameroonian propolis. To achieve our goal, the ability of EEP to induce MCF-7 cells proliferation in E-screen assay as well as to activate estrogen receptors α (ERα) and β (ERβ) in cell-based reporter gene assays using human embryonic kidney cells (HEK293T) transfected with ERs was tested. Further, a 3-day uterotrophic assay was performed and the ability of EEP to alleviate hot flushes in ovariectomized adult rats was evaluated. In vitro, EEP showed an antiestrogenic activity in both HEK293T ER-α and ER-β cells. In vivo, EEP induced a significant increase in a bell shape dose response manner of the uterine wet weight, the total protein levels in the uterus, the uterine and vaginal epithelium height and acini border cells of mammary gland with the presence of abundant eosinophil secretions. Moreover, EEP induced a significant decrease in the total number, average duration as well as frequency of hot flushes after 3 days of treatment in rat (equivalent to a month in woman). The dose of 150 mg/kg exhibited the most potent estrogenic effects among all the tested doses. The UPLC-HRMS analysis showed the presence of caffeic acid derivatives and trirtepernoids in EEP, which are well known endowed with estrogenic properties. These results suggest that Ethanolic extract of Cameroonian propolis has estrogen-like effects in vivo and may alleviate some menopausal problems such as vaginal dryness and hot flushes. Ethanol-extracted Cameroobian propolis exhibited in vitro and in vivo estrogen-like effects. This extract may contain promising phytoestrogens.

Supporting the education evidence portal via text mining

PubMed Central

Ananiadou, Sophia; Thompson, Paul; Thomas, James; Mu, Tingting; Oliver, Sandy; Rickinson, Mark; Sasaki, Yutaka; Weissenbacher, Davy; McNaught, John

2010-01-01

The UK Education Evidence Portal (eep) provides a single, searchable, point of access to the contents of the websites of 33 organizations relating to education, with the aim of revolutionizing work practices for the education community. Use of the portal alleviates the need to spend time searching multiple resources to find relevant information. However, the combined content of the websites of interest is still very large (over 500 000 documents and growing). This means that searches using the portal can produce very large numbers of hits. As users often have limited time, they would benefit from enhanced methods of performing searches and viewing results, allowing them to drill down to information of interest more efficiently, without having to sift through potentially long lists of irrelevant documents. The Joint Information Systems Committee (JISC)-funded ASSIST project has produced a prototype web interface to demonstrate the applicability of integrating a number of text-mining tools and methods into the eep, to facilitate an enhanced searching, browsing and document-viewing experience. New features include automatic classification of documents according to a taxonomy, automatic clustering of search results according to similar document content, and automatic identification and highlighting of key terms within documents. PMID:20643679

Equatorial Pacific peak in biological production regulated by nutrient and upwelling during the late Pliocene/early Pleistocene cooling

NASA Astrophysics Data System (ADS)

Etourneau, J.; Robinson, R. S.; Martinez, P.; Schneider, R.

2013-03-01

The largest increase in export production in the eastern Pacific of the last 5.3 Myr (million years) occurred between 2.2 and 1.6 Myr, a time of major climatic and oceanographic reorganization in the region. Here, we investigate the causes of this event using reconstructions of export production, nutrient supply and oceanic conditions across the Pliocene-Pleistocene in the eastern equatorial Pacific (EEP) for the last 3.2 Myr. Our results indicate that the export production peak corresponds to a cold interval marked by high nutrient supply relative to consumption, as revealed by the low bulk sedimentary 15N/14N (δ15N) and alkenone-derived sea surface temperature (SST) values. This ~ 0.6 million years long episode of enhanced delivery of nutrients to the surface of the EEP was predominantly initiated through the upwelling of nutrient-enriched water sourced in high latitudes. In addition, this phenomenon was likely promoted by the regional intensification of upwelling in response to the development of intense Walker and Hadley atmospheric circulations. Increased nutrient consumption in the polar oceans and enhanced denitrification in the equatorial regions restrained nutrient supply and availability and terminated the high export production event.

The Eczema Education Programme: intervention development and model feasibility.

PubMed

Jackson, K; Ersser, S J; Dennis, H; Farasat, H; More, A

2014-07-01

The systematic support of parents of children with eczema is essential to their effective management; however, we have few models of support. This study examines the rationale, evidence base and development of a large-scale, structured, theory-based, nurse-led intervention, the 'Eczema Education Programme' (EEP), for parents of children with eczema. To outline development of the EEP, model of delivery, determine its feasibility and evaluate this based on service access and parental satisfaction data. Parent-child dyads meeting EEP referral criteria were recruited and demographic information recorded. A questionnaire survey of parental satisfaction was conducted 4 weeks post EEP; parental focus groups at 6 weeks provided comparative qualitative data. Descriptive statistics were derived from the questionnaire data using Predictive Analytics Software (PASW); content analysis was applied to focus group data. A total of 356 parents attended the EEP during the evaluation period. Service access was achieved for those in a challenging population. Both survey data (n = 146 parents, 57%) and focus group data (n = 21) revealed a significant level of parental satisfaction with the programme. It was feasible to provide the EEP as an adjunct to normal clinical care on a large scale, achieving a high level of patient/parent satisfaction and access within an urban area of multiple deprivation and high mobility. The intervention is transferable and the results are generalizable to other ethnically diverse child eczema populations within metropolitan areas in Britain. A multicentre RCT is required to test the effectiveness of this intervention on a larger scale. © 2013 European Academy of Dermatology and Venereology.

A long history of equatorial deep-water upwelling in the Pacific Ocean

NASA Astrophysics Data System (ADS)

Zhang, Yi Ge; Pagani, Mark; Henderiks, Jorijntje; Ren, Haojia

2017-06-01

Cold, nutrient- and CO2-rich waters upwelling in the eastern equatorial Pacific (EEP) give rise to the Pacific cold tongue. Quasi-periodic subsidence of the thermocline and attenuation in wind strength expressed by El Niño conditions decrease upwelling rates, increase surface-water temperatures in the EEP, and lead to changes in regional climates both near and far from the equatorial Pacific. EEP surface waters have elevated CO2 concentrations during neutral (upwelling) or La Niña (strong upwelling) conditions. In contrast, approximate air-sea CO2 equilibrium characterizes El Niño events. One hypothesis proposes that changes in physical oceanography led to the establishment of a deep tropical thermocline and expanded mixed-layer prior to 3 million years ago. These effects are argued to have substantially reduced deep-water upwelling rates in the EEP and promoted a "permanent El Niño-like" climate state. For this study, we test this supposition by reconstructing EEP "excess CO2" and upwelling history for the past 6.5 million years using the alkenone-pCO2 methodology. Contrary to previous assertions, our results indicate that average temporal conditions in the EEP over the past ∼6.5 million years were characterized by substantial CO2 disequilibrium and high nutrient delivery to surface waters - characteristics that imply strong upwelling of deep waters. Upwelling appears most vigorous between ∼6.5 to 4.5 million years ago coinciding with high accumulation rates of biogenic material during the late Miocene - early Pliocene "biogenic bloom".

The Influence of Ethanolic Extract of Brazilian Green Propolis Gel on Hygiene and Oral Microbiota in Patients after Mandible Fractures

PubMed Central

Niedzielska, Iwona; Niedzielski, Damian; Różanowski, Bartosz; Konopka, Tomasz; Tanasiewicz, Marta; Paluch, Jarosław; Markowski, Jarosław; Orzechowska-Wylęgała, Bogusława; Król, Wojciech

2016-01-01

Maintenance of proper oral hygiene by dental plaque elimination is one of the most important factors affecting the healing process in postoperative oral wounds. Propolis is a substance produced by bees. Ethanolic extract of propolis has bactericidal, fungicidal, anti-inflammatory, and antioxidative properties. Moreover, it can scavenge free radicals. The purpose of this paper is to demonstrate the efficacy of a gel containing 3% of ethanolic extract of Brazilian green propolis (EEP-B) when used for maintaining oral hygiene in patients with postoperative oral mucosal wounds. The hygiene was assessed using API, OHI, and SBI followed by microbiological examinations. The patients were divided into two groups. Group 1 consisted of those who used a gel containing EEP-B for oral hygiene, and group 2 consisted of those who used a gel without EEP-B. Although improved oral hygiene was noted in both groups, the improvement was markedly greater in the group using gel containing EEP-B. Summing up the results of microbiological examinations, EEP-B has beneficial effect on mouth microflora in postoperative period. Propolis preparations used for oral hygiene allow eliminating microorganisms of pathogenic character and physiological flora microorganisms considered as being opportunistic, with no harmful influence on physiological microflora in oral ecosystem. PMID:27595110

Changes in thermocline structure in the Eastern Equatorial Pacific since the Last Glacial Maximum: A comparative study

NASA Astrophysics Data System (ADS)

McChesney, C. L.; Ford, H. L.; McManus, J. F.

2016-12-01

The Eastern Equatorial Pacific (EEP) is an important region of study due to its dynamic nature and role in El Niño-Southern Oscillation (ENSO), which is the biggest source of global interannual variability. The EEP is characterized by cool sea surface temperatures that are tightly coupled to a shallow thermocline. Variability in the depth of the EEP thermocline is important in initiating and propagating El Niño events. Here, we investigate changes in thermocline depth during the Last Glacial Maximum (LGM) to gain insight into how conditions within the EEP changed in the context of different boundary conditions (e.g., low CO2, greater ice volume). Using the stable oxygen isotope values of planktonic foraminifera from a range of calcification depths in the water column, we show that the thermocline was deep during the LGM relative to the Holocene at Ocean Drilling Program Site 849 (0°N, 110°W, 3839 m water depth). In comparison to previous studies that have been done in the region, site 849 has the smallest change of δ18O surface values, indicating less glacial cooling. However, site 849 displays even less apparent cooling in subsurface isotopic values, with a difference of -0.39 ‰ when comparing the LGM to the Holocene, suggesting little temperature change. The δ18O values of site 849 during the LGM had a smaller range between subsurface and surface foraminifera of 1.64‰ compared to the Holocene range of 2.11‰. This difference indicates that the thermocline was deeper in the equatorial cold tongue during the LGM. A deep thermocline may have inhibited some of the thermocline related feedbacks in ENSO variability and led to reduced ENSO during the LGM. Future Mg/Ca data will be incorporated to verify temperature.

7 CFR 1494.301 - Information required for program participation.

Code of Federal Regulations, 2011 CFR

2011-01-01

...—EEP Contacts: (1) The address of the interested person's office and the name and address of an agent... interested person, if the interested person is a corporation; (4) The name and address of an office(s) of the..., should any such debarment, suspension, or notice of proposed debarment occur in the future, [name of...

Sensory transduction of weak electromagnetic fields: role of glutamate neurotransmission mediated by NMDA receptors.

PubMed

Frilot, C; Carrubba, S; Marino, A A

2014-01-31

Subliminal electromagnetic fields (EMFs) triggered nonlinear evoked potentials in awake but not anesthetized animals, and increased glucose metabolism in the hindbrain. Field detection occurred somewhere in the head and possibly was an unrecognized function of sensory neurons in facial skin, which synapse in the trigeminal nucleus and project to the thalamus via glutamate-dependent pathways. If so, anesthetic agents that antagonize glutamate neurotransmission would be expected to degrade EMF-evoked potentials (EEPs) to a greater extent than agents having different pharmacological effects. We tested the hypothesis using ketamine which blocks N-methyl-d-aspartate (NMDA) receptors (NMDARs), and xylazine which is an α₂-adrenoreceptor agonist. Electroencephalograms (EEGs) of rats were examined using recurrence analysis to observe EEPs in the presence and absence of ketamine and/or xylazine anesthesia. Auditory evoked potentials (AEPs) served as positive controls. The frequency of observation of evoked potentials in a given condition (wake or anesthesia) was compared with that due to chance using the Fisher's exact test. EEPs were observed in awake rats but not while they were under anesthesia produced using a cocktail of xylazine and ketamine. In another experiment each rat was measured while awake and while under anesthesia produced using either xylazine or ketamine. EEPs and AEPs were detected during wake and under xylazine (P<0.05 in each of the four measurements). In contrast, neither EEPs nor AEPs were observed when anesthesia was produced partly or wholly using ketamine. The duration and latency of the EEPs was unaltered by xylazine anesthesia. The afferent signal triggered by the transduction of weak EMFs was likely mediated by NMDAR-mediated glutamate neurotransmission. Copyright © 2013 IBRO. Published by Elsevier Ltd. All rights reserved.

Chemical composition and antifungal potential of Brazilian propolis against Candida spp.

PubMed

Freires, I A; Queiroz, V C P P; Furletti, V F; Ikegaki, M; de Alencar, S M; Duarte, M C T; Rosalen, P L

2016-06-01

Propolis is known to have biological properties against numerous microorganisms of clinical interest. This study aimed to determine the chemical composition and antifungal activity of Brazilian propolis (types 3 and 13) against Candida spp. and their effects on the morphology of preformed and mature Candida biofilms. Samples of propolis (3 and 13) collected by Apis mellifera honeybees were obtained from different regions in Brazil. Ethanolic extracts of propolis (EEP) were prepared, fractionated and submitted to chemical analysis by GC/MS. The extracts and their hexane, dichloromethane and ethyl acetate fractions were tested for their ability to inhibit Candida spp. (C. albicans, C. dubliniensis, C. glabrata, C. kruzei, C. tropicalis and C. parapsilosis) by determination of the minimum inhibitory and fungicidal concentrations (MIC/MFC). Additionally, their effects on morphology of preformed and mature biofilms were observed by scanning electron microscopy. The phenolic compounds p-coumaric acid, caffeic acid phenethyl ester (CAPE), kaempferol and quercetin were identified in the EEP-3 and its bioactive dichloromethane fraction; and isoflavonoids such as medicarpin, vestitol and formononetin were found in the EEP-13, and triterpenes in its bioactive hexane fraction. The EEP-3 and EEP-13 and their bioactive fractions showed MIC values ranging from 0.2 to 125μg/mL and MFC values between 125 and 500μg/mL. The EEP and fractions were predominantly fungistatic agents. All extracts and fractions disrupted biofilm structures at 500μg/mL and amorphous areas with cell damage were clearly observed in preformed and mature biofilms. Propolis types 3 and 13 have strong anti-Candida activity and should be considered as promising candidates to treat oral and systemic candidiasis. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Antimicrobial, antioxidant and cytotoxic activities of propolis from Melipona orbignyi (Hymenoptera, Apidae).

PubMed

Campos, Jaqueline Ferreira; dos Santos, Uilson Pereira; Macorini, Luis Fernando Benitez; de Melo, Adriana Mary Mestriner Felipe; Balestieri, José Benedito Perrella; Paredes-Gamero, Edgar Julian; Cardoso, Claudia Andrea Lima; de Picoli Souza, Kely; dos Santos, Edson Lucas

2014-03-01

Propolis from stingless bees is well known for its biologic properties; however, few studies have demonstrated these effects. Therefore, this study aimed to investigate the chemical composition and antimicrobial, antioxidant and cytotoxic activities of propolis from the stingless bee Melipona orbignyi, found in Mato Grosso do Sul, Brazil. The chemical composition of the ethanol extract of propolis (EEP) indicated the presence of aromatic acids, phenolic compounds, alcohols, terpenes and sugars. The EEP was active against the bacterium Staphylococcus aureus and the fungus Candida albicans. The EEP showed antioxidant activity by scavenging free radicals and inhibiting hemolysis and lipid peroxidation in human erythrocytes incubated with an oxidizing agent. Additionally, EEP promoted cytotoxic activity and primarily necrotic death in K562 erythroleukemia cells. Taken together, these results indicate that propolis from M. orbignyi has therapeutic potential for the treatment and/or prevention of diseases related to microorganism activity, oxidative stress and tumor cell proliferation. Copyright © 2014 Elsevier Ltd. All rights reserved.

Shifting Climate Modes and a Warm Little Ice Age: Paleo Productivity and Temperature Determinations from the Southern California Current Over the Last Millennium

NASA Astrophysics Data System (ADS)

Kelly, C. S.; Herbert, T.; O'Mara, N. A.; Abella-Gutiérrez, J. L.; Herguera, J. C.

2016-12-01

The ocean dynamical thermostat hypothesis predicts that stronger [weaker] equatorial radiation forces warmer [cooler] western Pacific sea surface temperatures (SSTs) and a cooler [warmer] Eastern Equatorial Pacific (EEP) through air-sea coupling of the Walker circulation. Although proxy data offers some support for this prediction, recent SST reconstructions from the EEP suggest complex relationships between Northern Hemisphere (NH) and EEP temperature during the last millennium (Rustic et al. 2015), with EEP SSTs positively covarying with NH temperature during the Medieval Warm Period but negatively covarying during the Little Ice Age (LIA). Whereas most proxy reconstructions have focused on the EEP upwelling zone, few high-resolution studies exist from the California Current (CC)—a region whose oceanography displays exceptional fidelity to the El Niño Southern Oscillation and the Pacific Decadal Oscillation. In particular, southern CC oceanography reflects a balance between tropically-sourced and more northerly, temperate waters. Teasing these signals apart across past centuries can provide insight as to how a more complex dynamical thermostat affects the subtropics. Does the subtropical eastern Pacific track EEP SST across multiple centuries and climatic transitions? We present a record from the San Lazaro Basin (25N, 112.5W) in the subtropical eastern Pacific off Baja, Mexico of SST and marine paleoproductivity based upon alkenone saturation and concentrations (C37tot) over the last millennium. By combining these analyses on laminated sediment cores with newly published productivity records from the same site, we provide the first sub decadal paleoceanographic record from the southern California upwelling zone. We observe quasi-periodic short-lived cold excursions, centennial modulation of multidecadal periodicities, and an inverse relationship between C37tot and SST at lower frequencies. Our SST record displays a warm Little Ice Age, similar to but 100 years earlier than EEP warmth observed at 1500 CE (Rustic et al. 2015). In spite of this mismatch, the similarity between these records and the correlation of LIA warmth with NH cooling offers support for the dynamical thermostat's application in subtropical settings, provided they are plumbed to the equatorial climatology.

Comparison of electrically evoked cortical potential thresholds generated with subretinal or suprachoroidal placement of a microelectrode array in the rabbit

NASA Astrophysics Data System (ADS)

Yamauchi, Yasuyuki; Franco, Luisa M.; Jackson, Douglas J.; Naber, John F.; Ofer Ziv, R.; Rizzo, Joseph F., III; Kaplan, Henry J.; Enzmann, Volker

2005-03-01

The aim of the study was to directly compare the threshold electrical charge density of the retina (retinal threshold) in rabbits for the generation of electrical evoked potentials (EEP) by delivering electrical stimulation with a custom-made microelectrode array (MEA) implanted into either the subretinal or suprachoroidal space. Nine eyes of seven Dutch-belted rabbits were studied. The electroretinogram (ERG), visual evoked potentials (VEP) and EEP were recorded. Electrodes for the VEP and EEP were placed on the dura mater overlying the visual cortex. The EEP was recorded following electrical stimulation of the MEA placed either subretinally beneath the visual streak of the retina or in the suprachoroidal space in the rabbit eye. An ab externo approach was used for placement of the MEA. Liquid perfluorodecaline (PFCL; 0.4 ml) was placed within the vitreous cavity to flatten the neurosensory retina on the MEA after subretinal implantation. The retinal threshold for generation of an EEP was determined for each MEA placement by three consecutive measurements consisting of 100 computer-averaged recordings. Animals were sacrificed at the conclusion of the experiment and the eyes were enucleated for histological examination. The retinal threshold to generate an EEP was 9 ± 7 nC (0.023 ± 0.016 mC cm-2) within the subretinal space and 150 ± 122 nC (0.375 ± 0.306 mC cm-2) within the suprachoroidal space. Histology showed disruption of the outer retina with subretinal but not suprachoroidal placement. The retinal threshold to elicit an EEP is significantly lower with subretinal placement of the MEA compared to suprachoroidal placement (P < 0.05). The retinal threshold charge density with a subretinal MEA is well below the published charge limit of 1 mC cm-2, which is the level below which chronic stimulation of the retina is considered necessary to avoid tissue damage (Shannon 1992 IEEE Trans. Biomed. Eng. 39 424-6). Supported in part by The Charles D Kelman, MD Postdoctoral Scholar Award 2003 (YY); Boston VA Hospital (V523P-7278); Research to Prevent Blindness, New York City, NY and Kentucky Research Challenge Trust Fund (HJK).

Brazilian red propolis: phytochemical screening, antioxidant activity and effect against cancer cells.

PubMed

de Mendonça, Izabel Cristina Gomes; Porto, Isabel Cristina Celerino de Moraes; do Nascimento, Ticiano Gomes; de Souza, Naiana Soares; Oliveira, José Marcos dos Santos; Arruda, Rodolfo Elleson dos Santos; Mousinho, Kristiana Cerqueira; dos Santos, Aldenir Feitosa; Basílio-Júnior, Irinaldo Diniz; Parolia, Abhishek; Barreto, Francisco Stefânio

2015-10-14

The implementation of new public healthcare models that stimulate the use of natural products from traditional medicine, as a so-called integrated medicine, refers to an approach that use best of both conventional medicine and traditional medicine. Propolis is a widely used natural product by different ancient cultures and known to exhibit biological activities beneficial for health. The large number of studies conducted with propolis had shown that its chemical composition differs as a function of the climate, plant diversity and bee species and plays an important role on its therapeutic properties. The aim of this study was to analyse the phytochemical profile of the ethanolic extract of red propolis (EEP) and its fractionation, antioxidant action of EEP and its fractions hexane, cloroform and ethyl acetate and cytotoxic activity of EEP on human tumour cell lines SF-295 (glioblastoma), OVCAR-8 (ovary) and HCT-116 (colon). EEP was obtained by maceration with absolute ethanol, then it was concentrated in rotaevaporator up to complete evaporation of the solvent. The crude extract was fractionated with hexane, ethyl acetate, chloroform and methanol and they were subjected to phytochemical screening and total phenolic compounds. Antioxidant activity of EEP and fractions was done by means of the 2,2-diphenyl-1-picryhydrazyl (DPPH) method. Biomarkers of red propolis were identified by LC-Orbitrap-FTMS. To assess cytotoxic activity of the extract, cells were exposed to EEP over 72 h. Cell viability was assessed by means of MTT assay. The percentage of cell growth inhibition (IC50) was analysed by means of non-linear regression, and the absorbance values of the various investigated concentrations were subjected to one-factor analysis of variance (ANOVA) followed by Tukey's or Tamhane's tests (α = 0.05). The results obtained using phytochemical screening and LC-Orbitrap-FTMS indicated the presence of phlobaphene tannins, catechins, chalcones, aurones, flavonones, flavonols, xanthones, pentacyclic triterpenoids and guttiferones in Brazilian red propolis. EEP and its hexane, chloroform and ethyl acetate fractions obtained by liquid-liquid partitioning exhibited satisfactory antioxidant percentages. EEP (IC50 < 34.27 μg/mL) exhibited high levels of cytotoxicity on all human tumour cell lines tested when compared to negative control. C-Orbitrap-FTMS was useful to establish the chemical profile of the red propolis. Brazilian red propolis has antioxidant properties and decreases substantially the percentage of cell survival of human tumour cells; thus, it has potential to serve as an anticancer drug.

Anti-inflammatory activity and phenolic profile of propolis from two locations in Región Metropolitana de Santiago, Chile.

PubMed

Valenzuela-Barra, Gabriela; Castro, Consuelo; Figueroa, Catalina; Barriga, Andrés; Silva, Ximena; de Las Heras, Beatriz; Hortelano, Sonsoles; Delporte, Carla

2015-06-20

Propolis has long been used as a popular folk medicine due to its wide spectrum of alleged biological and pharmaceutical properties. In Chile, propolis is widely used by folklore medicine as an anti-inflammatory agent; however, this property has not been demonstrated by scientific methods. The objective of this study was to determine the anti-inflammatory activity in vivo and in vitro and to establish the phenolic profile of propolis collected in two localities in Región Metropolitana de Santiago (RM), Chile. Propolis was collected in the areas of Caleu and Buin, RM Chile. Following that, the samples were unwaxed to obtain the global ethanolic extracts of propolis (EEPs) and, from these, the serial extracts of dichloromethane (EEP-DCMs) and ethanol (EEP-EtOHs). The topic anti-inflammatory effect was evaluated through mice ear edema induced by arachidonic acid (AA) and 12-O-tetradecanoylphorbol-13-acetate (TPA) at a dose of 3 mg/ear. Nitric oxide (NO) measurements were determined spectrophotometrically (Greiss reagent) by the accumulation of nitrite in the medium of macrophages RAW 264.7 stimulated with the lipopolysaccharide (LPS, 1 μg/mL) for 20 h at different concentrations of the EEPs, EEP-DCMs and EEP-EtOHs (6.25-50.00 μg/mL). The content of total phenols and flavonoids were determined through the methods of Folin-Ciocalteau and AlCl3, respectively. The profile of phenolic compounds was determined by HPLC-UV-ESI-MS/MS. The EEP-EtOH (64%) and EEP (59%) of Buin were the most active in the inflammation induced by TPA and AA respectively, being the anti-inflammatory effect stronger than the same Caleu extracts. Regarding the release of NO, all the extracts from the Buin propolis inhibited significantly its release in a concentration-dependent manner, this inhibition was stronger than the extracts from Caleu propolis. Our research shows for the first time a comparative study of the topical in vivo activity of two Chilean propolis. Both propolis showed in vivo topical anti-inflammatory activity against AA and TPA, the most active was Buin propolis and this difference is due in part to the variations in total phenols and flavonoids content and the phenolic profile. The phenols and flavonoids content of Buin propolis was higher than Caleu propolis. The extracts from Buin propolis result in a lower release of NO. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Joint Communications Support Element: The Voice Heard Round the World

DTIC Science & Technology

2013-01-01

Initial Entry Package ( IEP ), Early Entry Package (EEP), and Joint Mobil- ity Package provide secure and nonsecure voice, video, and data to small mobile...teams operating worldwide. The IEP and EEP can be rapidly scaled to meet force surge require- ments from small dismounted teams up to an advance

Equatorial Pacific peak in biological production regulated by nutrient and upwelling during the late Pliocene/early Pleistocene cooling

NASA Astrophysics Data System (ADS)

Etourneau, J.; Robinson, R. S.; Martinez, P.; Schneider, R.

2013-08-01

The largest increase in export production in the eastern Pacific of the last 5.3 Myr (million years) occurred between 2.2 and 1.6 Myr, a time of major climatic and oceanographic reorganization in the region. Here, we investigate the causes of this event using reconstructions of export production, nutrient supply and oceanic conditions across the Pliocene-Pleistocene in the eastern equatorial Pacific (EEP) for the last 3.2 Myr. Our results indicate that the export production peak corresponds to a cold interval marked by high nutrient supply relative to consumption, as revealed by the low bulk sedimentary 15N/14N (δ15N) and alkenone-derived sea surface temperature (SST) values. This ∼0.6 million year long episode of enhanced delivery of nutrients to the surface of the EEP was predominantly initiated through the upwelling of nutrient-enriched water sourced in high latitudes. In addition, this phenomenon was likely promoted by the regional intensification of upwelling in response to the development of intense Walker and Hadley atmospheric circulations. Increased nutrient consumption in the polar oceans and enhanced denitrification in the equatorial regions restrained nutrient supply and availability and terminated the high export production event.

Late Neogene Orbitally-Forced Sea Surface Temperature Variability in the Eastern Equatorial Pacific as Measured by Uk'37 and TEX86

NASA Astrophysics Data System (ADS)

Lawrence, K. T.; Pearson, A.; Castañeda, I. S.; Peterson, L.

2017-12-01

Key features of late Neogene climate remain uncertain due to conflicting records derived from different sea surface temperature (SST) proxies. To resolve these disputes, it is necessary to explore both the consistencies and differences between paleotemperature estimates from critical oceanographic regimes. Here, we report orbital-scale climate variability at ODP Site 846 in the Eastern Equatorial Pacific (EEP) in the interval from 5-6 Ma using alkenone and TEX86 temperature estimates. Results from both proxies are very similar in their secular trends and magnitude of long-term temperature change; and spectral analysis demonstrates that the records are coherent and in-phase or nearly in-phase in both the obliquity and precession bands. However, we find that the temperatures reconstructed by TEX86 are consistently offset towards colder values by 2ºC with orbital-scale variations approximately twice the amplitude of the Uk'37 derived estimates. Both temperature records are antiphased - i.e. "colder" - at higher sediment alkenone concentrations, a qualitative indicator of increased glacial productivity. Temperature differences between the proxies are accentuated during glacial intervals in contrasts to modern observations of EEP surface and subsurface temperatures, which show that thermocline temperatures are fairly stable, and thus by analogy, glacial cooling and/or enhanced upwelling should have reduced rather than accentuated temperature gradients in the upper water column. Therefore, arguments that Uk'37 corresponds to temperature variability in the surface, while TEX86 responds to the subsurface, may be too simplistic. Instead, it appears generally true that high-productivity environments, including the EEP, tend to have negative TEX86 anomalies. This may reflect a dual dependence of TEX86 records on both water column temperature and local productivity. Overall, our data suggest that in the EEP and likely in other upwelling zones, paleotemperature data derived from these proxies should not necessarily be used interchangeably and only Uk'37 is suitable for determining absolute SSTs. However, our data also suggest that TEX86 may be suitable for estimating long-term trends in SST and for spectral and phase analysis in upwelling regimes.

Antimicrobial Activities of European Propolis Collected from Various Geographic Origins Alone and in Combination with Antibiotics

PubMed Central

AL-Ani, Issam; Zimmermann, Stefan; Reichling, Jürgen

2018-01-01

Background: Propolis consists of a complex mixture of resinous substances collected by honeybees from different plant sources. The objective of this study was to investigate the chemical composition, biological activities, and synergistic properties with antibiotics of propolis samples collected from various geographic origins (Germany, Ireland, and Czech Republic). Methods: The chemical composition of the propolis was analyzed by Gas Liquid Chromatography-Mass Spectrometry (GLC-MS) and High-performance liquid chromatography (HPLC). The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) were evaluated by the standard broth microdilution method, while synergistic interactions were assessed by checkerboard dilution and time-kill curve assays. Results: HPLC and GLC-MS analyses revealed that ethanol extract of propolis (EEP) and water extracts of propolis (WEP) contained more than 100 different phytochemicals. The most abundant compounds were aromatic alcohols, aromatic acids, cinnamic acid and its esters, fatty acids, and flavanone (chrysin). Czech propolis showed the highest phenolic content (129.83 ± 5.9 mg CAE/g) followed by Irish propolis and German propolis. Furthermore, Irish propolis exhibited the highest value of total flavonoid content (2.86 ± 0.2 mg QE/g) and antioxidant activity (IC50 = 26.45 µg/mL). All propolis samples showed moderate antibacterial effect against Gram-positive microorganisms with MIC ranging from 0.08 mg/mL to 2.5 mg/mL. Moreover, EEP exhibited moderate activity against Gram-negative bacteria with MIC between 0.6 mg/mL to 5 mg/mL. In addition, EEP displayed moderate antifungal activity (MIC values between 0.6–2.5 mg/mL). The results obtained from time kill-kinetic assay and checkerboard dilution test of two-drug combinations between EEP and antibiotics such as vancomycin, oxacillin, and levofloxacin indicate mainly synergistic interactions against drug-resistant microbial pathogens including MRSA and VRE. Conclusions: The propolis extract synergistically enhanced the efficacy of antibiotics, especially those acting on cell wall synthesis (vancomycin and oxacillin) against drug-resistant microorganisms. PMID:29301368

Increase in nitrite content and functionality of ethanolic extracts of Perilla frutescens following treatment with atmospheric pressure plasma.

PubMed

Jung, Samooel; Lee, Chul Woo; Lee, Juri; Yong, Hae In; Yum, Su Jin; Jeong, Hee Gon; Jo, Cheorun

2017-12-15

This study investigated the effect of atmospheric pressure plasma (APP) treatment on nitrite content and functionality of plant extracts. Ethanolic extracts of Perilla frutescens (EEP) were prepared and treated with APP for 60min. Nitrite content increased from 0 to 45.8mg/l in EEP after APP treatment for 60min. Antimicrobial activity of EEP against Clostridium perfringens and Salmonella Typhimurium was increased by APP with no influence on antioxidative activity (p<0.05). Lyophilized EEP (LEEP) treated with APP for 60min contained 3.74mg/g nitrite. The control (LEEP without APP) contained no nitrite. The minimum inhibitory concentration (MIC) of LEEP for C. perfringens was 200µg/ml. The control did not inhibit C. perfringens growth between 25 and 1000µg/ml. MICs of LEEP and the control against S. Typhimurium were 25 and 50µg/ml, respectively. New nitrite sources with increased antimicrobial activity can be produced from natural plants by APP treatment. Copyright © 2017 Elsevier Ltd. All rights reserved.

Ecological Engineering Practices for the Reduction of Excess Nitrogen in Human-Influenced Landscapes: A Guide for Watershed Managers

NASA Astrophysics Data System (ADS)

Passeport, Elodie; Vidon, Philippe; Forshay, Kenneth J.; Harris, Lora; Kaushal, Sujay S.; Kellogg, Dorothy Q.; Lazar, Julia; Mayer, Paul; Stander, Emilie K.

2013-02-01

Excess nitrogen (N) in freshwater systems, estuaries, and coastal areas has well-documented deleterious effects on ecosystems. Ecological engineering practices (EEPs) may be effective at decreasing nonpoint source N leaching to surface and groundwater. However, few studies have synthesized current knowledge about the functioning principles, performance, and cost of common EEPs used to mitigate N pollution at the watershed scale. Our review describes seven EEPs known to decrease N to help watershed managers select the most effective techniques from among the following approaches: advanced-treatment septic systems, low-impact development (LID) structures, permeable reactive barriers, treatment wetlands, riparian buffers, artificial lakes and reservoirs, and stream restoration. Our results show a broad range of N-removal effectiveness but suggest that all techniques could be optimized for N removal by promoting and sustaining conditions conducive to biological transformations (e.g., denitrification). Generally, N-removal efficiency is particularly affected by hydraulic residence time, organic carbon availability, and establishment of anaerobic conditions. There remains a critical need for systematic empirical studies documenting N-removal efficiency among EEPs and potential environmental and economic tradeoffs associated with the widespread use of these techniques. Under current trajectories of N inputs, land use, and climate change, ecological engineering alone may be insufficient to manage N in many watersheds, suggesting that N-pollution source prevention remains a critical need. Improved understanding of N-removal effectiveness and modeling efforts will be critical in building decision support tools to help guide the selection and application of best EEPs for N management.

Nanoemulsion of ethanolic extracts of propolis and its antioxidant activity

NASA Astrophysics Data System (ADS)

Mauludin, R.; Primaviri, D. S.; Fidrianny, I.

2015-09-01

Propolis contains several antioxidant compounds which can be used in topical application to protect skin against free radical and prevent skin cancer and skin aging. Ethanolic extracts of propolis (EEP) provided the greatest antioxidant activity but has very small solubility in water thus was prepared in nanoemulsion (NE). EEP contains steroid/triterpenoid, flavonoid, and saponin. EEP had the value of DPPH scavenging activity 61.14% and IC50 0.41629 ppm. The best NE formulation consisted of 26.25% Kolliphor RH40; 8.75% glycerin; 5% rice bran oil; and 3% EEP. NE was transparent, had particle size of 23.72 nm and polydispersity index of 0.338. Based on TEM morphology, NE was almost spherical and has particle size below 50 nm. NE propolis revealed to be physically stable after stability test within 63 days at 25°C and passed 6 cycles of Freeze and Thaw test without separated. NE propolis reduced around 58% of free radical DPPH similar to antioxidant activity of the original extracts. Antioxidant activity of NE propolis is relatively stable after stored for 6 weeks. NE propolis was proven to be safe by primary irritation test with the value of primary irritation index (OECD) was 0.

Anticancer Activity of Indian Stingless Bee Propolis: An In Vitro Study

PubMed Central

Choudhari, Milind K.; Haghniaz, Reihaneh; Rajwade, Jyutika M.; Paknikar, Kishore M.

2013-01-01

Indian stingless bee propolis has a complex chemical nature and is reported to possess various medicinal properties. In the present study, anticancer activity of the ethanolic extract of propolis (EEP) was explored by testing the cytotoxic and apoptotic effect in four different cancer cell lines, namely, MCF-7 (human breast cancer), HT-29 (human colon adenocarcinoma), Caco-2 (human epithelial colorectal adenocarcinoma), and B16F1 (murine melanoma), at different concentrations. Cytotoxicity was evaluated by MTT assay and Trypan blue dye exclusion assay. EEP at a concentration of 250 μg/mL exhibited ≥50% mortality in all cell lines tested (i.e., IC50 value). EEP revealed a concentration and time dependent cytotoxic effect. Apoptosis was estimated by differential staining (ethidium bromide/acridine orange) and TUNEL (deoxynucleotidyl transferase-dUTP nick end labeling) assay. Light microscopy and atomic force microscopy demonstrated morphological features of apoptosis in all the cell lines after treatment with 250 μg/mL EEP for 24 h. Thus, early onset of apoptosis is the reason for anticancer activity of Indian stingless bee propolis. Further, the antioxidant potential of Indian stingless bee propolis was demonstrated to substantiate its anticancer activity. PMID:23762169

Anticancer activity of Indian stingless bee propolis: an in vitro study.

PubMed

Choudhari, Milind K; Haghniaz, Reihaneh; Rajwade, Jyutika M; Paknikar, Kishore M

2013-01-01

Indian stingless bee propolis has a complex chemical nature and is reported to possess various medicinal properties. In the present study, anticancer activity of the ethanolic extract of propolis (EEP) was explored by testing the cytotoxic and apoptotic effect in four different cancer cell lines, namely, MCF-7 (human breast cancer), HT-29 (human colon adenocarcinoma), Caco-2 (human epithelial colorectal adenocarcinoma), and B16F1 (murine melanoma), at different concentrations. Cytotoxicity was evaluated by MTT assay and Trypan blue dye exclusion assay. EEP at a concentration of 250 μg/mL exhibited ≥50% mortality in all cell lines tested (i.e., IC50 value). EEP revealed a concentration and time dependent cytotoxic effect. Apoptosis was estimated by differential staining (ethidium bromide/acridine orange) and TUNEL (deoxynucleotidyl transferase-dUTP nick end labeling) assay. Light microscopy and atomic force microscopy demonstrated morphological features of apoptosis in all the cell lines after treatment with 250 μg/mL EEP for 24 h. Thus, early onset of apoptosis is the reason for anticancer activity of Indian stingless bee propolis. Further, the antioxidant potential of Indian stingless bee propolis was demonstrated to substantiate its anticancer activity.

Influence of the Toothpaste with Brazilian Ethanol Extract Propolis on the Oral Cavity Health

PubMed Central

Skaba, Dariusz; Morawiec, Tadeusz; Tanasiewicz, Marta; Bobela, Elżbieta; Skucha-Nowak, Małgorzata; Dawiec, Monika; Yamamoto, Rindai; Makita, Yuki; Redzynia, Małgorzata; Janoszka, Beata; Niedzielska, Iwona; Król, Wojciech

2013-01-01

Propolis-based therapeutic agents represent this potential for the development of new drugs in dental care. The aim of a clinical-cohort study was to determine the influence of application of toothpaste enriched with Brazilian extract of propolis (EEP) on health status of oral cavity. Laboratory analysis was conducted in order to assess the chemical composition of EEP including total phenolic compounds, the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity, ABTS radical cation scavenging activity, and FRAP assay. Clinical research involved two groups of subjects comprising 32 adult patients, with assessment based on the preliminary evaluation of the state of their marginal periodontium. The investigation of oral health indices API, OHI, and SBI and microbiological examination of oral microflora were also carried out. Results obtained indicated time-dependent microbial action of EEP at 50 mg/L concentration, with antimicrobial activity against Gram-positive bacteria. The total decrease of API, OHI, and SBI mean values was observed. Hygienic preparations with 3% content of Brazilian ethanol extract of green propolis (EEP) efficiently support removal of dental plaque and improve the state of marginal periodontium. PMID:23861699

The mechanisms of orbital and suborbital-scale productivity variations in the Eastern Equatorial Pacific

NASA Astrophysics Data System (ADS)

Ivanova, E. V.; Beaufort, L.; Vidal, L.

2009-04-01

The Eastern Equatorial Pacific (EEP) is known to exhibit high seasonal, interannual (ENSO-like) and longer-term climatic variability with possible worldwide consequences, however, the origin of the suborbital-scale changes in the region is still enigmatic. The centennial to millennial scale variations in the foraminiferal-based MAT-derived SST, productivity index (FP index estimated as the total faunal portion of the three productivity-related planktic foraminiferal species) and coccolithophore-based quantitative productivity record are investigated over MIS 3 and three glacial-interglacial terminations in the IMAGES Core MD02-2529 off Costa Rica (8°12.5' N, 84° 07.5' W, w.d. 1619 m). The stratigraphic framework over three climatic cycles is based on the benthic d 18O record performed on C. wuellerstorfi, and on the published time-scale for last 90 ka (Leduc et al. 2007). The results of the study provide new insight on the mechanisms of productivity variations in the EEP. FP index and total planktic foraminiferal abundance increase concurrently with the previously established salinity raise (Leduc et al.2007) at six H-events (from H-6 to H-1) and at the Younger Dryas relative to the adjacent values. SST record does not show any consistent positive or negative correlation with H-events. The longer-lasting events of enhanced FP index values associate with all three terminations, whereas SST and the total portion of foraminiferal oligotrophic species increase by the end of terminations. The recurrent increase in bioproductivity during H-events may be interpreted in terms of intensified nutrients supply at the core site. At present, bioproductivity at site MD02-2529 is influenced by the seasonal cycle and associated shifts of the Costa Rica Dome and by propagation of eddies and filaments from the nearby coastal upwellings in the Panama Bight and Gulf of Papagayo with the Ekman drift. As these seasonal upwellings are known to be driven by coastal wind jets associated with the northeast trade winds, they might be intensified during the H-events. The strengthening of the northeast trade winds and coastal jets could also affect the migrations of the Costa Rica Dome. The strengthening of the northeast trade winds in turn is in line with southward ITCZ shifts during the H-events suggested by several authors. Enhanced productivity may also result from a shallowing of pycnocline due to reduced moisture supply from the Caribbean and corresponding increase in sea- surface salinity at H-events at site MD02-2529 demonstrated by Leduc and co-authors (2008). Thus, changes in surface water salinity and bioproductivity in the EEP seem to reflect mainly the atmospheric teleconnections with the high northern latitudes during several intervals of the AMOC slowdown. On the other hand, the intervals of enhanced foraminiferal abundance and FP index corresponds to the intervals of maximum PP values estimated from coccolithophore assemblages over terminations which call on the shallow pycnocline and to more persistent La Nina-like conditions. The spectral analysis demonstrates the significant precessional control of both coccolithophore and foraminiferal-based productivity records. The productivity shifts at terminations are also coeval with the intervals of depleted carbon isotope values measured on subsurface planktic foraminifera in the EEP. As the shifts in carbon isotopes were previously interpreted by several authors in terms of nutrients advection from the Southern Ocean to the EEP at thermocline level the concurrent increase in bioproductivity may result from this oceanic teleconnection between the two regions associated with the reorganization of the THC over terminations. Hence, unlike the short-term productivity increase at H-events the longer-lasting shifts over terminations may imply different mechanisms including the orbital (mainly precessional) control, ENSO-like variability and oceanic teleconnections.

Influence of a Brazilian wild green propolis on the enamel mineral loss and Streptococcus mutans' count in dental biofilm.

PubMed

Cardoso, Julia Gabiroboertz; Iorio, Natalia Lopes Pontes; Rodrigues, Luís Fernando; Couri, Maria Luiza Barra; Farah, Adriana; Maia, Lucianne Cople; Antonio, Andréa Gonçalves

2016-05-01

This study investigated the anti-demineralizing and antibacterial effects of a propolis ethanolic extract (EEP) against Streptococcus mutans dental biofilm. Blocks of sound bovine enamel (n=24) were fixed on polystyrene plates. S. mutans inoculum (ATCC 25175) and culture media were added (48 h-37 °C) to form biofilm. Blocks with biofilm received daily treatment (30 μL/1 min), for 5 days, as following: G1 (EEP 33.3%); G2 (chlorhexidine digluconate 0.12%); G3 (ethanol 80%); and G4 (Milli-Q water). G5 and G6 were blocks without biofilm that received only EEP and Milli-Q water, respectively. Final surface hardness was evaluated and the percentage of hardness loss (%HL) was calculated. The EEP extract pH and total solids were determined. S. mutans count was expressed by log10 scale of Colony-Forming Units (CFU/mL). One way ANOVA was used to compare results which differed at a 95% significance level. G2 presented the lowest average %HL value (68.44% ± 12.98) (p=0.010), while G4 presented the highest (90.49% ± 5.38%HL) (p=0.007). G1 showed %HL (84.41% ± 2.77) similar to G3 (87.80% ± 6.89) (p=0.477). Groups G5 and G6 presented %HL=16.11% ± 7.92 and 20.55% ± 10.65; respectively (p=0.952). G1 and G4 differed as regards to S. mutans count: 7.26 ± 0.08 and 8.29 ± 0.17 CFU/mL, respectively (p=0.001). The lowest bacterial count was observed in chlorhexidine group (G2=6.79 ± 0.10 CFU/mL) (p=0.043). There was no difference between S. mutans count of G3 and G4 (p=0.435). The EEP showed pH 4.8 and total soluble solids content=25.9 Brix. The EEP seems to be a potent antibacterial substance against S. mutans dental biofilm, but presented no inhibitory action on the de-remineralization of caries process. Copyright © 2016 Elsevier Ltd. All rights reserved.

Mid-depth respired carbon storage and oxygenation of the eastern equatorial Pacific over the last 25,000 years

NASA Astrophysics Data System (ADS)

Umling, Natalie E.; Thunell, Robert C.

2018-06-01

A growing body of evidence suggests that respired carbon was stored in mid-depth waters (∼1-3 km) during the last glacial maximum (LGM) and released to the atmosphere from upwelling regions during deglaciation. Decreased ventilation, enhanced productivity, and enhanced carbonate dissolution are among the mechanisms that have been cited as possible drivers of glacial CO2 drawdown. However, the relative importance of each of these mechanisms is poorly understood. New approaches to quantitatively constrain bottom water carbonate chemistry and oxygenation provide methods for estimating historic changes in respired carbon storage. While increased CO2 drawdown during the LGM should have resulted in decreased oxygenation and a shift in dissolved inorganic carbon (DIC) speciation towards lower carbonate ion concentrations, this is complicated by the interplay of carbonate compensation, export productivity, and circulation. To disentangle these processes, we use a multiproxy approach that includes boron to calcium (B/Ca) ratios of the benthic foraminifera Cibicidoides wuellerstorfi to reconstruct deep-water carbonate ion concentrations ([CO32-]) and the uranium to calcium (U/Ca) ratio of foraminiferal coatings in combination with benthic foraminiferal carbon isotopes to reconstruct changes in bottom water oxygen concentrations ([O2]) and organic carbon export. Our records indicate that LGM [CO32-] and [O2] was reduced at mid water depths of the eastern equatorial Pacific (EEP), consistent with increased respired carbon storage. Furthermore, our results suggest enhanced mixing of lower Circumpolar Deep Water (LCDW) to EEP mid water depths and provide evidence for the importance of circulation for oceanic-atmospheric CO2 exchange.

[The endo-exo prosthesis treatment concept : Improvement in quality of life after limb amputation].

PubMed

Hoffmeister, T; Schwarze, F; Aschoff, H H

2017-05-01

Osseointegrated, percutaneous implants as the force bearer for exoprosthetics after limb amputation have been used in individual cases for clinical rehabilitation of amputees during the past years. Most experience in this field in Germany has been accumulated at the Sana Klinik in Lübeck with the so-called endo-exo prosthesis (EEP) system. The two-step implantation procedure can now be considered as reliable. Following a well-documented learning curve initial soft tissue problems concerning the cutaneous stoma can now be regarded as exceptions. The retrospective examination of the results concerning by now more than 100 patients provided with an endo-exo femoral prosthesis (EEFP) showed a very satisfying outcome concerning objective as well as subjective values, such as duration of daily use and wearing comfort of the exoprosthesis. Regaining the ability of osseoperception due to the intraosseous fixation is described by the patients as a great advantage. The step from a socket prosthesis to an EEP is felt to be a big increase in quality of life by nearly all patients included into the follow-up. Nearly all of the patients questioned would choose an endo-exo prosthesis again. Meanwhile, the success of the EEP resulted in the broadening of indications from above-knee amputations to transtibial as well as transhumeral amputations. The results are likewise encouraging. The use of EEP for the upper limbs leads to substantial improvement in the range of motion of the shoulder joint with the intramedullary anchored percutaneous implant. Furthermore, new pathbreaking possibilities in the fixation of myoelectrically controlled arm prostheses may arise from the EEP technique.

Main pathways of action of Brazilian red propolis on the modulation of neutrophils migration in the inflammatory process.

PubMed

Bueno-Silva, Bruno; Franchin, Marcelo; Alves, Claudiney de Freitas; Denny, Carina; Colón, David Fernando; Cunha, Thiago Mattar; Alencar, Severino Matias; Napimoga, Marcelo Henrique; Rosalen, Pedro Luiz

2016-12-01

Brazilian propolis is popularly used as treatment for different diseases including the ones with inflammatory origin. Brazilian red propolis chemical profile and its anti-inflammatory properties were recently described however, its mechanism of action has not been investigated yet. Elucidate Brazilian red propolis major pathways of action on the modulation of neutrophil migration during the inflammatory process. The ethanolic extract of propolis (EEP) activity was investigated for neutrophil migration into the peritoneal cavity, intravital microscopy (rolling and adhesion of leukocytes), quantification of cytokines TNF-α, IL-1β and chemokines CXCL1/KC, CXCL2/MIP-2, neutrophil chemotaxis induced by CXCL2/MIP-2, calcium influx and CXCR2 expression on neutrophils. EEP at 10mg/kg prevented neutrophil migration into peritoneal cavity (p < 0.05), reduced leukocyte rolling and adhesion on the mesenteric microcirculation (p < 0.05) and inhibited the release TNF-α, IL-1β, CXCL1/KC and CXCL2/MIP-2 (p < 0.05). EEP at 0.01, 0.1 and 1µg/ml reduced the CXCL2/MIP-2-induced neutrophils chemotaxis (p < 0.05) without affect cell viability (p > 0.05).EEP at 1µg/ml decreased the calcium influx induced by CXCL2/MIP-2 (p<0.05). On the other hand, none of EEP concentrations tested altered CXCR2 expression by neutrophils (p>0.05). Brazilian red propolis appears as a promising anti-inflammatory natural product which mechanism seems to be by reducing leukocyte rolling and adhesion; TNF-α, IL-1β, CXCL1/KC and CXCL2/MIP-2 release; CXCL2/MIP-2-induced chemotaxis and calcium influx. Copyright © 2016 Elsevier GmbH. All rights reserved.

Effects of ethanol and water extracts of propolis (bee glue) on acute inflammatory animal models.

PubMed

Hu, Fuliang; Hepburn, H R; Li, Yinghua; Chen, M; Radloff, S E; Daya, S

2005-09-14

The anti-inflammatory effects of ethanol (EEP) and water (WSD) extracts in ICR mice and Wistar rats were analyzed. Both WSD and EEP exhibited significant anti-inflammatory effects in animal models with respect to thoracic capillary vessel leakage in mice, carrageenan-induced oedema, carrageenan-induced pleurisy, acute lung damage in rats. The mechanisms for the anti-inflammatory effects probably involve decreasing prostaglandin-E(2) (PGE(2)) and nitric oxide (NO) levels. In rats with Freund's complete adjuvant (FCA) induced arthritis, propolis extracts significantly inhibited the increase of interleukin-6 (IL-6) in inflamed tissues, but had no significant effect on levels of interleukin-2 (IL-2) and interferon-gamma (IFN-gamma). The results are consistent with the interpretation that EEP and WSD may exert these effects by inhibiting the activation and differentiation of mononuclear macrophages.

NEPHROPATHIES IN THE EUROPEAN CAPTIVE CHEETAH (ACINONYX JUBATUS) POPULATION.

PubMed

Url, Angelika; Krutak, Verena; Kübber-Heiss, Anna; Chvala-Mannsberger, Sonja; Robert, Nadia; Dinhopl, Nora; Schmidt, Peter; Walzer, Chris

2016-09-01

According to previous studies in captive cheetah ( Acinonyx jubatus ) populations, one of the most threatening diseases besides amyloidosis, myelopathy, veno occlusive disease, and gastritis, is renal failure. Contrary to captive cheetahs in North America and South Africa, morphological data concerning renal lesions in the cheetah European Endangered Species Program (EEP) are lacking. This study details the histological characterization as well as immunohistochemical and morphometrical analysis of nephropathies in 35 captive cheetahs from the EEP, which were necropsied between 1985 and 2003. Examination of paraffin- and glycolmethacrylate-methylmethacrylate (GMA-MMA) embedded kidney samples by light microscopy revealed glomerulonephritis in 91%, with a high prevalence for glomerulosclerosis and glomerulonephritis with the histologic pattern of membranous glomerulonephritis (77%). Besides these predominating glomerulopathies, a wide range of other renal lesions, like acute tubular necrosis, interstitial nephritis, calcinosis, and amyloidosis, were present. Pathological expression of collagen type IV, complement C3, fibronectin, and IgG was demonstrated in the glomeruli of the cheetah kidneys with the use of the avidin-biotin complex method. Morphometrical analysis was performed on GMA-MMA embedded kidney samples to obtain glomerulosclerosis index and glomerulosclerosis incidence.

Effects of disturbance and climate change on ecosystem performance in the Yukon River Basin boreal forest

USGS Publications Warehouse

Wylie, Bruce K.; Rigge, Matthew B.; Brisco, Brian; Mrnaghan, Kevin; Rover, Jennifer R.; Long, Jordan

2014-01-01

A warming climate influences boreal forest productivity, dynamics, and disturbance regimes. We used ecosystem models and 250 m satellite Normalized Difference Vegetation Index (NDVI) data averaged over the growing season (GSN) to model current, and estimate future, ecosystem performance. We modeled Expected Ecosystem Performance (EEP), or anticipated productivity, in undisturbed stands over the 2000–2008 period from a variety of abiotic data sources, using a rule-based piecewise regression tree. The EEP model was applied to a future climate ensemble A1B projection to quantify expected changes to mature boreal forest performance. Ecosystem Performance Anomalies (EPA), were identified as the residuals of the EEP and GSN relationship and represent performance departures from expected performance conditions. These performance data were used to monitor successional events following fire. Results suggested that maximum EPA occurs 30–40 years following fire, and deciduous stands generally have higher EPA than coniferous stands. Mean undisturbed EEP is projected to increase 5.6% by 2040 and 8.7% by 2070, suggesting an increased deciduous component in boreal forests. Our results contribute to the understanding of boreal forest successional dynamics and its response to climate change. This information enables informed decisions to prepare for, and adapt to, climate change in the Yukon River Basin forest.

Simultaneous Dual Species Matter Wave Interferometry

NASA Astrophysics Data System (ADS)

Schlippert, Dennis; Albers, Henning; Richardson, Logan; Meiners, Christian; Hartwig, Jonas; Ertmer, Wolfgang; Rasel, Ernst

2014-05-01

We report on the first realization of a simultaneous 39K-87Rb-dual species matter wave interferometer measuring gravitational acceleration with the aim to test Einstein's Equivalence Principle (EEP). Compared to classical tests such as torsion pendulum experiments and Lunar Laser Ranging, chemical elements suitable for performing matter wave interferometry can provide complementary information. We show the performance of our apparatus and discuss current limitations and future improvements towards highly sensitive matter wave tests of EEP.

Anti-proliferative and anti-migration effects of Polish propolis combined with Hypericum perforatum L. on glioblastoma multiforme cell line U87MG.

PubMed

Borawska, Maria H; Naliwajko, Sylwia K; Moskwa, Justyna; Markiewicz-Żukowska, Renata; Puścion-Jakubik, Anna; Soroczyńska, Jolanta

2016-09-20

Propolis and Hypericum perforatum L. are natural products which contain many active compounds and have numerous beneficial effects, including an antitumor effect. Gliobmastoma multiforme (GBM) is a common primary brain tumor with poor prognosis and limited treatment options. In this study, the effect of propolis (EEP) combined with H. perforatum L. (HPE) on glioblastoma cell line U87MG was investigated for the first time. Anti-proliferative activity of EEP, HPE and their combination (EEP + HPE) was determined by a cytotoxicity test, DNA binding by [(3)H]-thymidine incorporation and cell migration assay. Anti-metastatic properties in U87MG treated with EEP, HPE and EEP + HPE were estimated on cells migration test (scratch assay) and metalloproteinases (MMP2 and MMP9) secretion (gelatin zymography). Combination of HPE and EEP extracts was found to have a time- and dose-dependent inhibitory effect on the viability of U87MG cells. This effect was significantly higher (p < 0.05) when compared to these two extracts applied separately, which was confirmed by the significant reduction of DNA synthesis and significantly higher mitochondrial membrane permeabilization. A significant decreasing in migration cells and in pro-MMP9 and pro-MMP2 secretion in U87MG cells were demonstrated after exposure to combination of EEP (30 μg/ml) with HPE (6.25 μg/ml). In this study, the combination of ethanolic extract from propolis and ethanolic extract of fresh-cut H. perforatum L. was proved the ability to reduce invasiveness of glioma cells through the inhibition of MMP2 and MMP9 secretion and suppression of cell migration. It has a more potent anti-proliferative effect on U87MG glioma cell line compared to using propolis and H. perforatum L. separately. Further studies are required to verify whether the examined extracts can activate apoptotic pathways.

Incidence of virulence determinants in clinical Enterococcus faecalis and Enterococcus faecium isolates collected in Bulgaria.

PubMed

Strateva, Tanya; Atanasova, Daniela; Savov, Encho; Petrova, Guergana; Mitov, Ivan

2016-01-01

To evaluate the prevalence of some virulence genes among 510 clinical Enterococcus spp. isolates and to assess the association of those genes with the species, infection site, and patient group (inpatients/outpatients). Adhesins genes (aggregation substances agg and asa1 of Enterococcus faecalis and Enterococcus faecium, respectively), enterococcal surface protein (esp), endocarditis-specific antigen A (efaA), collagen-binding proteins (ace/acm)); invasins (hyaluronidase (hyl) and gelatinase (gelE)); cytotoxines (activation of cytolysin (cylA) in E. faecalis); and modulators of the host immunity and inflammation (enhanced expression pheromone (eep) in E. faecalis) were detected by polymerase chain reaction. The overall prevalence was: esp - 44.3%, agg/asa1 - 38.4%, ace/acm - 64.3%, efaA - 85.9%, eep - 69.4%, gelE - 64.3%, hyl - 25.1%, and cylA - 47.1%. E. faecalis isolates had significantly higher frequency of adhesin genes (esp and agg/asa1) and gelatinase in comparison to E. faecium. Multiple virulence genes in E. faecalis were significantly more prevalent than in E. faecium isolates. Domination of E. faecium with or without only one gene compared to the isolates of E. faecalis were found. Enterococcus spp. isolates obtained from outpatients compared to inpatients isolates had significantly higher frequency of agg/asa1, eep, gelE and cylA. Some adhesins genes (esp, agg/asa1 and efaA) had higher prevalence among the non-invasive Enterococcus spp. isolates compared to those causing invasive bacteremia, while ace/acm revealed higher dissemination in isolates causing invasive infections compared to non-invasive isolates. Most E. faecalis attaches to abiotic surfaces in hospital environment, which correlates with higher prevalence of gene encoding for virulence factors involved in biofilm formation, such as enterococcal surface protein, aggregation substance, and gelatinase. The intestinal tract is an important reservoir for opportunistic enterococcal pathogens and allows them to access infectious sites through different virulence factors, demonstrated in outpatient isolates in this study. Copyright © 2016 Elsevier Editora Ltda. All rights reserved.

Testing Einstein's Equivalence Principle With Fast Radio Bursts

NASA Astrophysics Data System (ADS)

Wei, Jun-Jie; Gao, He; Wu, Xue-Feng; Mészáros, Peter

2015-12-01

The accuracy of Einstein's equivalence principle (EEP) can be tested with the observed time delays between correlated particles or photons that are emitted from astronomical sources. Assuming as a lower limit that the time delays are caused mainly by the gravitational potential of the Milky Way, we prove that fast radio bursts (FRBs) of cosmological origin can be used to constrain the EEP with high accuracy. Taking FRB 110220 and two possible FRB/gamma-ray burst (GRB) association systems (FRB/GRB 101011A and FRB/GRB 100704A) as examples, we obtain a strict upper limit on the differences of the parametrized post-Newtonian parameter γ values as low as [γ (1.23 GHz )-γ (1.45 GHz )] <4.36 ×10-9. This provides the most stringent limit up to date on the EEP through the relative differential variations of the γ parameter at radio energies, improving by 1 to 2 orders of magnitude the previous results at other energies based on supernova 1987A and GRBs.

Inhibition of toll-like receptor 3-4 with ethanolic extract of propolis on innate immunity in diabetes mellitus mice (Mus musculus)

NASA Astrophysics Data System (ADS)

Pristiwanto, Bambang; Soewondo, A.; Sumitro, Sutiman B.; Rifa'i, Muhaimin

2017-05-01

One of the most significant problems today is to treat the effects of metabolic diseases, such as diabetes. Thus, this study evaluated the ability of an ethanolic extract of propolis (EEP) to reduce inflammation in diabetes treatment. The used mice with STZ-induced diabetes mellitus (SID) and the expression of Toll-Like Receptor 3-4 was analyzed in their innate immunity cells. The SID mice had a higher TLR 3-4 expression compared with the healthy control group. Treatment of EEP in SID using three different doses significantly decreased the number of B cells with TLR 3-4 expression. This suggesting that EEP treatment decreases TLR3 & TLR4 expression on innate immunity (especially B cells) from over expression in SID which can affect the acute inflammatory and aggravate the diabetes condition. Even relatively low doses of propolis extract can decrease TLR3 and TLR4 expressed by B cell.

Testing Einstein's Equivalence Principle With Fast Radio Bursts.

PubMed

Wei, Jun-Jie; Gao, He; Wu, Xue-Feng; Mészáros, Peter

2015-12-31

The accuracy of Einstein's equivalence principle (EEP) can be tested with the observed time delays between correlated particles or photons that are emitted from astronomical sources. Assuming as a lower limit that the time delays are caused mainly by the gravitational potential of the Milky Way, we prove that fast radio bursts (FRBs) of cosmological origin can be used to constrain the EEP with high accuracy. Taking FRB 110220 and two possible FRB/gamma-ray burst (GRB) association systems (FRB/GRB 101011A and FRB/GRB 100704A) as examples, we obtain a strict upper limit on the differences of the parametrized post-Newtonian parameter γ values as low as [γ(1.23  GHz)-γ(1.45  GHz)]<4.36×10(-9). This provides the most stringent limit up to date on the EEP through the relative differential variations of the γ parameter at radio energies, improving by 1 to 2 orders of magnitude the previous results at other energies based on supernova 1987A and GRBs.

Antimicrobial activity of stingless bee (Trigona sp.) propolis used in the folk medicine of Western Maharashtra, India.

PubMed

Choudhari, Milind K; Punekar, Sachin A; Ranade, Ramchandra V; Paknikar, Kishore M

2012-05-07

Stingless bee (Trigona sp.) propolis is widely used in the folk medicine of Western Maharashtra, India to treat a variety of ailments. To determine the chemical composition and evaluate the antimicrobial activity of Indian stingless bee propolis. Chemical composition of the ethanolic extract of propolis (EEP) was determined by GC-MS analysis. A range of bacteria including multidrug resistant (MDR) cultures as well as a yeast strain was tested for antimicrobial activity using EEP. MIC, MBC, MFC, Kill curves and post agent effect (PAE) of the EEP were assessed using standard microbiological methods. GC-MS analysis revealed that propolis contained 24 compounds (9 known and 15 newly reported). Many of these were known bioactive compounds, including antimicrobials. The MICs of EEP were in the range of 1.21-9.75μg/mL while the MBCs/MFC were between 2.43 and 19.5μg/mL. The time required to achieve 90% (1 log(10)) reduction in culture growth ranged between 1.06 and 3.53h at their respective MIC values. PAE for all the cultures was >24h. Indian stingless bee propolis has a complex nature with 24 chemical compounds. It has a potent broad-spectrum antimicrobial activity. The latter finding, in conjunction with other bioactive properties, could provide a scientific basis to its popular use in the Indian folk medicine. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

The Antibacterial Effect of Ethanol Extract of Polish Propolis on Mutans Streptococci and Lactobacilli Isolated from Saliva

PubMed Central

Dziedzic, Arkadiusz; Kubina, Robert; Wojtyczka, Robert D.; Kabała-Dzik, Agata; Tanasiewicz, Marta; Morawiec, Tadeusz

2013-01-01

Dental caries occurrence is caused by the colonization of oral microorganisms and accumulation of extracellular polysaccharides synthesized by Streptococcus mutans with the synergistic influence of Lactobacillus spp. bacteria. The aim of this study was to determine ex vivo the antibacterial properties of ethanol extract of propolis (EEP), collected in Poland, against the main cariogenic bacteria: salivary mutans streptococci and lactobacilli. The isolation of mutans streptococci group bacteria (MS) and Lactobacillus spp. (LB) from stimulated saliva was performed by in-office CRT bacteria dip slide test. The broth diffusion method and AlamarBlue assay were used to evaluate the antimicrobial activity of EEP, with the estimation of its minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The biochemical composition of propolis components was assessed. The mean MIC and MBC values of EEP, in concentrations ranging from 25 mg/mL to 0.025 mg/mL, for the MS and LB were found to be 1.10 mg/mL versus 0.7 mg/mL and 9.01 mg/mL versus 5.91 mg/mL, respectively. The exposure to an extract of Polish propolis affected mutans streptococci and Lactobacillus spp. viability, exhibiting an antibacterial efficacy on mutans streptococci group bacteria and lactobacilli saliva residents, while lactobacilli were more susceptible to EEP. Antibacterial measures containing propolis could be the local agents acting against cariogenic bacteria. PMID:23606887

Evidence for a Southern Pattern of Deglacial Surface Warming in the Eastern Equatorial Pacific

NASA Astrophysics Data System (ADS)

Spero, H. J.; Schmidt, M. W.; Lea, D. W.; Lavagnino, L.

2009-12-01

The timing of both Southern and Northern hemisphere warming patterns has been used to explain tropical Pacific warming at the end of the last glacial period. Despite the importance of resolving this deglacial tropical-polar connection, the controversy is still ongoing (Koutavas & Sachs, 2008; Lea et al., 2000, 2006). For instance, the initiation of eastern equatorial Pacific (EEP) surface warming, derived from Mg/Ca analyses of the surface-dwelling foraminifera Globigerinoides ruber, shows a clear correlation with the Southern hemisphere. In contrast, alkenone-derived temperatures from the EEP indicate tropical warming occurred at least 3 kyr later than that implied from Mg/Ca data, thereby suggesting a Northern hemisphere link to initial SST rise. Here, we use a multispecies, multiproxy approach that is based on fundamental foraminifera biology to resolve this controversy. Laboratory experiments demonstrate the final shell size of symbiont-bearing foraminifera varies primarily as a function of the light level (=symbiont photosynthetic rate) that an individual grew under. Because light decreases exponentially in the water column, and the EEP is highly stratified with a shallow mixed layer and cold thermocline, we hypothesize that symbiotic foraminifera with a broad habitat range such as Globigerinoides sacculifer, should produce smaller shells in the more dimly lit cold thermocline than individuals growing in the more illuminated mixed layer. Moreover, these larger shells should contain a temperature signal that is similar to G. ruber, which is constrained to the shallow mixed layer. Mg/Ca and δ18O analyses conducted on 350-400 μm and >650 μm sized G. sacculifer from EEP core TR163-19 (2N, 91W, 2348) demonstrate large specimens yield Mg/Ca and δ18O that are similar to data published previously for mixed layer dwelling G. ruber. In contrast, small G. sacculifer record significantly higher δ18O and lower Mg/Ca temperatures that are consistent with a shallow thermocline habitat. More important, the timing of warming for the large G. sacculifer is similar to that of G. ruber, whereas thermocline temperatures recorded by small G. sacculifer increase nearly 3 kyr later, in close agreement with alkenone temperature change. These results link EEP surface warming to the Southern hemisphere and suggest that 1) early deglacial alkenone data are recording thermocline rather than mixed layer temperatures and 2) EEP thermocline temperature increase is more closely linked to Northern, rather than Southern hemisphere dynamics.

Comparison between POES energetic electron precipitation observations and riometer absorptions: Implications for determining true precipitation fluxes

NASA Astrophysics Data System (ADS)

Rodger, Craig J.; Kavanagh, Andrew J.; Clilverd, Mark A.; Marple, Steve R.

2013-12-01

electron precipitation (EEP) impacts the chemistry of the middle atmosphere with growing evidence of coupling to surface temperatures at high latitudes. To better understand this link, it is essential to have realistic observations to properly characterize precipitation and which can be incorporated into chemistry-climate models. The Polar-orbiting Operational Environmental Satellite (POES) detectors measure precipitating particles but only integral fluxes and only in a fraction of the bounce loss cone. Ground-based riometers respond to precipitation from the whole bounce loss cone; they measure the cosmic radio noise absorption (CNA), a qualitative proxy with scant direct information on the energy flux of EEP. POES observations should have a direct relationship with ΔCNA and comparing the two will clarify their utility in studies of atmospheric change. We determined ionospheric changes produced by the EEP measured by the POES spacecraft in ~250 overpasses of an imaging riometer in northern Finland. The ΔCNA modeled from the POES data is 10-15 times less than the observed ΔCNA when the >30 keV flux is reported as <106 cm-2 s-1 sr-1. Above this level, there is relatively good agreement between the space-based and ground-based measurements. The discrepancy occurs mostly during periods of low geomagnetic activity, and we contend that weak diffusion is dominating the pitch angle scattering into the bounce loss cone at these times. A correction to the calculation using measurements of the trapped flux considerably reduces the discrepancy and provides further support to our hypothesis that weak diffusion leads to underestimates of the EEP.

Ex vivo immunomodulatory effect of ethanolic extract of propolis during Celiac Disease: involvement of nitric oxide pathway.

PubMed

Medjeber, Oussama; Touri, Kahina; Rafa, Hayet; Djeraba, Zineb; Belkhelfa, Mourad; Boutaleb, Amira Fatima; Arroul-Lammali, Amina; Belguendouz, Houda; Touil-Boukoffa, Chafia

2018-03-07

Celiac Disease (CeD) is a chronic immune-mediated enteropathy, in which dietary gluten induces an inflammatory reaction, predominantly in the duodenum. Propolis is a resinous hive product, collected by honeybees from various plant sources. Propolis is well-known for its anti-inflammatory, anti-oxidant and immunomodulatory effects, due to its major compounds, polyphenols and flavonoids. The aim of our study was to assess the ex vivo effect of ethanolic extract of propolis (EEP) upon the activity and expression of iNOS, along with IFN-γ and IL-10 production in Algerian Celiac patients. In this context, PBMCs isolated from peripheral blood of Celiac patients and healthy controls were cultured with different concentrations of EEP. NO production was measured using the Griess method, whereas quantitation of IFN-γ and IL-10 levels was performed by ELISA. Inducible nitric oxide synthase (iNOS) expression, NFκB and pSTAT-3 activity were analyzed by immunofluorescence assay. Our results showed that PBMCs from Celiac patients produced high levels of NO and IFN-γ compared with healthy controls (HC). Interestingly, EEP reduced significantly, NO and IFN-γ levels and significantly increased IL-10 levels at a concentration of 50 µg/mL. Importantly, EEP downmodulated the iNOS expression as well as the activity of NFκB and pSTAT-3 transcription factors. Altogether, our results highlight the immunomodulatory effect of propolis on NO pathway and on pro-inflammatory cytokines. Therefore, we suggest that propolis may constitute a potential candidate to modulate inflammation during Celiac Disease and has a potential therapeutic value.

E and F Layer H.F. Volume Backscatter Reflectivities.

DTIC Science & Technology

1980-02-01

organization , please notify RADC (EEP), Hanscom AFB MA 01731. This will assist us in maintaining a current mailing list. Do not return this copy. Retain...6rd F19628-8C06 9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT. PROJECT. TASKARE A & WORK UNIT NUMBERS Deputy for Electronic Technology...p&U?4 and executeA weeath, devetopment, tet and ee.ted atcqu1,6tion p’wgAam6 in a6uppo’cL 06 Command, ContAot Coffexmlico.tionI and InteLigence (C31

Concentration-Dependent Protection by Ethanol Extract of Propolis against γ-Ray-Induced Chromosome Damage in Human Blood Lymphocytes.

PubMed

Montoro, A; Barquinero, J F; Almonacid, M; Montoro, A; Sebastià, N; Verdú, G; Sahuquillo, V; Serrano, J; Saiz, M; Villaescusa, J I; Soriano, J M

2011-01-01

Radioprotection with natural products may be relevant to the mitigation of ionizing radiation-induced damage in mammalian systems; in this sense, propolis extracts have shown effects such as antioxidant, antitumoral, anti-inflammatory, and immunostimulant. We report for the first time a cytogenetic study to evaluate the radioprotective effect, in vitro, of propolis against radiation-induced chromosomal damage. Lymphocytes were cultured with increasing concentrations of ethanol extract of propolis (EEP), including 20, 40, 120, 250, 500, 750, 1000, and 2000 μg mL(-1) and then exposed to 2 Gy γ-rays. A significant and concentration-dependent decrease is observed in the frequency of chromosome aberrations in samples treated with EEP. The protection against the formation of dicentrics was concentration-dependent, with a maximum protection at 120 μg mL(-1) of EEP. The observed frequency of dicentrics is described as negative exponential function, indicating that the maximum protectible fraction of dicentrics is approximately 44%. Free radical scavenging and antioxidant activities are the mechanisms that these substances use to protect cells from ionizing radiation.

Concentration-Dependent Protection by Ethanol Extract of Propolis against γ-Ray-Induced Chromosome Damage in Human Blood Lymphocytes

PubMed Central

Montoro, A.; Barquinero, J. F.; Almonacid, M.; Montoro, A.; Sebastià, N.; Verdú, G.; Sahuquillo, V.; Serrano, J.; Saiz, M.; Villaescusa, J. I.; Soriano, J. M.

2011-01-01

Radioprotection with natural products may be relevant to the mitigation of ionizing radiation-induced damage in mammalian systems; in this sense, propolis extracts have shown effects such as antioxidant, antitumoral, anti-inflammatory, and immunostimulant. We report for the first time a cytogenetic study to evaluate the radioprotective effect, in vitro, of propolis against radiation-induced chromosomal damage. Lymphocytes were cultured with increasing concentrations of ethanol extract of propolis (EEP), including 20, 40, 120, 250, 500, 750, 1000, and 2000 μg mL−1 and then exposed to 2 Gy γ-rays. A significant and concentration-dependent decrease is observed in the frequency of chromosome aberrations in samples treated with EEP. The protection against the formation of dicentrics was concentration-dependent, with a maximum protection at 120 μg mL−1 of EEP. The observed frequency of dicentrics is described as negative exponential function, indicating that the maximum protectible fraction of dicentrics is approximately 44%. Free radical scavenging and antioxidant activities are the mechanisms that these substances use to protect cells from ionizing radiation. PMID:20981159

Comparative Study of Chemical Composition and Biological Activity of Yellow, Green, Brown, and Red Brazilian Propolis

PubMed Central

Machado, Christiane Schineider; Mokochinski, João Benhur; de Lira, Tatiana Onofre; de Oliveira, Fátima de Cassia Evangelista; Cardoso, Magda Vieira; Ferreira, Roseane Guimarães; Sawaya, Alexandra Christine Helena Frankland; Ferreira, Antonio Gilberto; Pessoa, Cláudia; Cuesta-Rubio, Osmany; Monteiro, Marta Chagas; de Campos, Mônica Soares

2016-01-01

The chemical composition and biological activity of a sample of yellow propolis from Mato Grosso do Sul, Brazil (EEP-Y MS), were investigated for the first time and compared with green, brown, and red types of Brazilian propolis and with a sample of yellow propolis from Cuba. Overall, EEP-Y MS had different qualitative chemical profiles, as well as different cytotoxic and antimicrobial activities when compared to the other types of propolis assessed in this study and it is a different chemotype of Brazilian propolis. Absence of phenolic compounds and the presence of mixtures of aliphatic compounds in yellow propolis were determined by analysing 1H-NMR spectra and fifteen terpenes were identified by GC-MS. EEP-Y MS showed cytotoxic activity against human tumour strain OVCAR-8 but was not active against Gram-negative or Gram-positive bacteria. Our results confirm the difficulty of establishing a uniform quality standard for propolis from diverse geographical origins. The most appropriate pharmacological applications of yellow types of propolis must be further investigated. PMID:27525023

Experimental test of the mechanism of reaction for (e,e'p) coincidence experiment. [/sup 12/C(e,e'p): DWIA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bernheim, M.; Bussiere, A.; Frullani, S.

1977-06-27

In order to test the validity of the distorted wave impulse approximation to describe (e,e'p) reactions and/or the suitability of the available optical potential parameters to calculate the distortion, the spectral function was measured for /sub 12/C(e,e'p)/sub 11/B in different kinematical configurations. Experimental results are shown together with the distributions computed with several values of the optical potential parameters. Data seem to indicate the necessity of using different parameters for p hole states and s hole states.

Retrospective study of mortality in Asiatic lions (Panthera leo persica) in the European breeding population between 2000 and 2014.

PubMed

Metz, Olivia; Williams, Jonathan; Nielsen, Rikke Kruse; Masters, Nic

2017-01-01

Although the European population of Asiatic lions (Panthera leo persica) has been managed under the European Endangered Species Program (EEP) since 1990, little is known about the health status of the population. This study was designed to characterize mortality for this population through examination of the studbook and other records on 392 Asiatic lions living in the EEP between 2000 and 2014. A total of 270 animals died during the period with 80% of them being under 1 year old. The mortality rate for under 1 year olds was 54%, while the odds of survival of cubs within a litter increased if the dam had had litters previously. Survival to reproductive age was 44%. Post-mortem reports were requested and the cause of death was obtained for 133 animals. Trauma inflicted by a conspecific and lack of care were common causes of death (26% and 22%, respectively) and were also responsible for most of the neonatal mortalities. Congenital defects were responsible for 9% of deaths, although the true prevalence is likely underestimated. A common necropsy protocol for all Asiatic lion collections is needed to facilitate future studies. Zoo Biol. 36:66-73, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Is the Core Top Really Modern? A Story of Chemical Erosion, Bioturbation, and Lateral Sediment Redistribution from the Eastern Equatorial Pacific

NASA Astrophysics Data System (ADS)

Mekik, F.

2016-12-01

Paleoceanographic work is based on calibrating paleo-environmental proxies using well-preserved core top sediments which represent the last one thousand years or less. However, core top sediments may be in places as old as 9000 years due to various sedimentary and diagenetic processes, such as chemical erosion, bioturbation and lateral sediment redistribution. We hypothesize that in regions with high surface ocean productivity, high organic carbon to calcite ratios reaching the seabed promote calcite dissolution in sediments, even in regions above the lysocline. This process may lead to chemical erosion of core tops which in turn may result in core top aging. The eastern equatorial Pacific (EEP), a popular site for calibration of paleoceanographic proxies, is such a place. Better understanding the relationship between core top age and dissolution will help correct biases inherent in proxy calibration because dissolution of foraminifers alters shell chemistry, and wholesale dissolution of sediments leads to core top aging and loss. We present both new and literature-based core top data of radiocarbon ages from the EEP. We created regional maps of both core top radiocarbon age and calcite preservation measured with the Globorotalia menardii Fragmentation Index (MFI; over 100 core tops). Our maps show a clear pattern of deep sea sedimentary calcite dissolution mimicking the pattern of surface ocean productivity observed from satellites and sediment traps in the EEP. Core top radiocarbon ages generally parallel the dissolution patterns observed in the region. Where this relationship does not hold true, bioturbation and/or lateral sediment redistribution may play a role. Down core radiocarbon and 230Th-normalized sediment accumulation rate data from several cores in the EEP support this hypothesis. Better understanding the role of diagenesis promotes the development of more reliable paleo-environmental proxies.

[Are we prepared for a disaster? Spanish multicentre study].

PubMed

Parra Cotanda, C; Asensio Carretero, S; Trenchs Sainz de la Maza, V; Luaces Cubells, C

2012-09-01

Paediatric Emergency Departments (PED) should have written disaster plans, to ensure a rapid and efficient response. 1) to determine if Spanish PED have written disaster plans, 2) to describe the characteristics of these plans, and 3) if paediatric victims were included in them. Descriptive multicentre study based on questionnaires sent to physicians in charge of different Spanish PED. The structured survey included questions about external emergency plans (EEP) and internal emergency plans (IEP). Twenty-five out of 44 surveys were replied. Eighteen PED had an EEP, most of them had been written 10 years ago and were reviewed every 3 years or more. In 11/18 PED, the EEP was well-known by health care providers. Drills were never performed in 13/18 PED. Twenty-one PED had an IEP, most of them had been written 8 years ago and were reviewed every 3 years or more. In 13/21 PED, IEP was well-known by health care providers but drills were never performed in 12/21 PED. IEP included evacuation plans (22), fire emergency plans (19), bomb threat plan (13) and flood plans (9). Nine PED have paediatric-specific disaster plans and in 7 PED, disaster plans included adult and paediatric victims. Children were not included In 1 EEP and in 5 IEP. Most of PED have written disaster plans, but these plans are old, unknown by health care providers and almost half of them do not include paediatric victims. It is necessary to improve disaster planning in Spanish PED. Copyright © 2011 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

[Early results in the treatment of Legg-Calvé-Perthes disease using intra-articular injections of aqueous propolis extract].

PubMed

Przybylski, J; Scheller, S

1985-01-01

Authors presented results in conservative treatment of 54 cases of hip joint with aseptic necrosis of thigh bone. In 22 hips, excluding the typical conservative treatment, EEP injections were given. However, in the remaining 32, different forms of relieve were used. The obtained results in the first group (A) confirm the purpose of enrichment in conservative treatment by adapting intra- articular injections of EEP especially in advanced stages of necrosis (III-IV period of illness) and also in those whose parents did not express their consent on surgery in the early stage of the illness.

Mid-Pliocene equatorial Pacific sea surface temperature reconstruction: a multi-proxy perspective

USGS Publications Warehouse

Dowsett, Harry J.; Robinson, Marci M.

2009-01-01

The Mid-Pliocene is the most recent interval of sustained global warmth, which can be used to examine conditions predicted for the near future. An accurate spatial representation of the low-latitude Mid-Pliocene Pacific surface ocean is necessary to understand past climate change in the light of forecasts of future change. Mid-Pliocene sea surface temperature (SST) anomalies show a strong contrast between the western equatorial Pacific (WEP) and eastern equatorial Pacific (EEP) regardless of proxy (faunal, alkenone and Mg/Ca). All WEP sites show small differences from modern mean annual temperature, but all EEP sites show significant positive deviation from present-day temperatures by as much as 4.4°C. Our reconstruction reflects SSTs similar to modern in the WEP, warmer than modern in the EEP and eastward extension of the WEP warm pool. The east-west equatorial Pacific SST gradient is decreased, but the pole to equator gradient does not change appreciably. We find it improbable that increased greenhouse gases (GHG) alone would cause such a heterogeneous warming and more likely that the cause of Mid-Pliocene warmth is a combination of several forcings including both increased meridional heat transport and increased GHG.

Mid-Pliocene equatorial Pacific sea surface temperature reconstruction: A multi-proxy perspective

USGS Publications Warehouse

Dowsett, H.J.; Robinson, M.M.

2009-01-01

The Mid-Pliocene is the most recent interval of sustained global warmth, which can be used to examine conditions predicted for the near future. An accurate spatial representation of the low-latitude Mid-Pliocene Pacific surface ocean is necessary to understand past climate change in the light of forecasts of future change. Mid-Pliocene sea surface temperature (SST) anomalies show a strong contrast between the western equatorial Pacific (WEP) and eastern equatorial Pacific (EEP) regardless of proxy (faunal, alkenone and Mg/Ca). All WEP sites show small differences from modern mean annual temperature, but all EEP sites show significant positive deviation from present-day temperatures by as much as 4.4??C. Our reconstruction reflects SSTs similar to modern in the WEP, warmer than modern in the EEP and eastward extension of the WEP warm pool. The east-west equatorial Pacific SST gradient is decreased, but the pole to equator gradient does not change appreciably. We find it improbable that increased greenhouse gases (GHG) alone would cause such a heterogeneous warming and more likely that the cause of Mid-Pliocene warmth is a combination of several forcings including both increased meridional heat transport and increased GHG. ?? 2008 The Royal Society.

Ecosystem performance monitoring of rangelands by integrating modeling and remote sensing

USGS Publications Warehouse

Wylie, Bruce K.; Boyte, Stephen P.; Major, Donald J.

2012-01-01

Monitoring rangeland ecosystem dynamics, production, and performance is valuable for researchers and land managers. However, ecosystem monitoring studies can be difficult to interpret and apply appropriately if management decisions and disturbances are inseparable from the ecosystem's climate signal. This study separates seasonal weather influences from influences caused by disturbances and management decisions, making interannual time-series analysis more consistent and interpretable. We compared the actual ecosystem performance (AEP) of five rangeland vegetation types in the Owyhee Uplands for 9 yr to their expected ecosystem performance (EEP). Integrated growing season Normalized Difference Vegetation Index data for each of the nine growing seasons served as a proxy for annual AEP. Regression-tree models used long-term site potential, seasonal weather, and land cover data sets to generate annual EEP, an estimate of ecosystem performance incorporating annual weather variations. The difference between AEP and EEP provided a performance measure for each pixel in the study area. Ecosystem performance anomalies occurred when the ecosystem performed significantly better or worse than the model predicted. About 14% of the Owyhee Uplands showed a trend of significant underperformance or overperformance (P<0.10). Land managers can use results from weather-based rangeland ecosystem performance models to help support adaptive management strategies.

Antimicrobial, Antioxidant, Anti-Inflammatory, and Cytotoxic Activities of Propolis from the Stingless Bee Tetragonisca fiebrigi (Jataí).

PubMed

Campos, Jaqueline Ferreira; Dos Santos, Uilson Pereira; da Rocha, Paola Dos Santos; Damião, Marcio José; Balestieri, José Benedito Perrella; Cardoso, Claudia Andrea Lima; Paredes-Gamero, Edgar Julian; Estevinho, Leticia Miranda; de Picoli Souza, Kely; Dos Santos, Edson Lucas

2015-01-01

Propolis from stingless bees Tetragonisca fiebrigi found in Brazil is used in folk medicine by their nutritional and therapeutic properties. However, there are no scientific records evidencing such properties. The present study was designed to investigate the chemical composition and the biological properties of propolis from T. fiebrigi. For this, the chemical composition of the ethanol extract of propolis (EEP) was determined by GC-MS and presented phenolic compounds, alcohol, and terpenes as its major class compounds. The antimicrobial activity was accessed in gram-positive and gram-negative bacteria and in fungi, isolated from different biological fluids and reference strains. The EEP was active against all microorganisms and showed antioxidant activity by scavenging free radicals, inhibiting hemolysis and lipid peroxidation in human erythrocytes incubated with an oxidizing agent. The anti-inflammatory potential of the EEP was confirmed by inhibition of the hyaluronidase enzyme. The cytotoxic activity was concentration-dependent against K562 cells, with a predominance of death by necrosis. Taken together, these results show that propolis from T. fiebrigi has important therapeutic activities, which suggest its potential application in the pharmaceutical industry, as well as in health foods, beverages, and nutritional supplements.

Mid-Pliocene equatorial Pacific sea surface temperature reconstruction: a multi-proxy perspective.

PubMed

Dowsett, Harry J; Robinson, Marci M

2009-01-13

The Mid-Pliocene is the most recent interval of sustained global warmth, which can be used to examine conditions predicted for the near future. An accurate spatial representation of the low-latitude Mid-Pliocene Pacific surface ocean is necessary to understand past climate change in the light of forecasts of future change. Mid-Pliocene sea surface temperature (SST) anomalies show a strong contrast between the western equatorial Pacific (WEP) and eastern equatorial Pacific (EEP) regardless of proxy (faunal, alkenone and Mg/Ca). All WEP sites show small differences from modern mean annual temperature, but all EEP sites show significant positive deviation from present-day temperatures by as much as 4.4 degrees C. Our reconstruction reflects SSTs similar to modern in the WEP, warmer than modern in the EEP and eastward extension of the WEP warm pool. The east-west equatorial Pacific SST gradient is decreased, but the pole to equator gradient does not change appreciably. We find it improbable that increased greenhouse gases (GHG) alone would cause such a heterogeneous warming and more likely that the cause of Mid-Pliocene warmth is a combination of several forcings including both increased meridional heat transport and increased GHG.

Climate and marine biogeochemistry during the Holocene from transient model simulations

NASA Astrophysics Data System (ADS)

Segschneider, Joachim; Schneider, Birgit; Khon, Vyacheslav

2018-06-01

Climate and marine biogeochemistry changes over the Holocene are investigated based on transient global climate and biogeochemistry model simulations over the last 9500 years. The simulations are forced by accelerated and non-accelerated orbital parameters, respectively, and atmospheric pCO2, CH4, and N2O. The analysis focusses on key climatic parameters of relevance to the marine biogeochemistry, and on the physical and biogeochemical processes that drive atmosphere-ocean carbon fluxes and changes in the oxygen minimum zones (OMZs). The simulated global mean ocean temperature is characterized by a mid-Holocene cooling and a late Holocene warming, a common feature among Holocene climate simulations which, however, contradicts a proxy-derived mid-Holocene climate optimum. As the most significant result, and only in the non-accelerated simulation, we find a substantial increase in volume of the OMZ in the eastern equatorial Pacific (EEP) continuing into the late Holocene. The concurrent increase in apparent oxygen utilization (AOU) and age of the water mass within the EEP OMZ can be attributed to a weakening of the deep northward inflow into the Pacific. This results in a large-scale mid-to-late Holocene increase in AOU in most of the Pacific and hence the source regions of the EEP OMZ waters. The simulated expansion of the EEP OMZ raises the question of whether the deoxygenation that has been observed over the last 5 decades could be a - perhaps accelerated - continuation of an orbitally driven decline in oxygen. Changes in global mean biological production and export of detritus remain of the order of 10 %, with generally lower values in the mid-Holocene. The simulated atmosphere-ocean CO2 flux would result in atmospheric pCO2 changes of similar magnitudes to those observed for the Holocene, but with different timing. More technically, as the increase in EEP OMZ volume can only be simulated with the non-accelerated model simulation, non-accelerated model simulations are required for an analysis of the marine biogeochemistry in the Holocene. Notably, the long control experiment also displays similar magnitude variability to the transient experiment for some parameters. This indicates that also long control runs are required when investigating Holocene climate and marine biogeochemistry, and that some of the Holocene variations could be attributed to internal variability of the atmosphere-ocean system.

Thermocline Temperature Variability Reveals Shifts in the Tropical Pacific Mean State across Marine Isotope Stage 3

NASA Astrophysics Data System (ADS)

Hertzberg, J. E.; Schmidt, M. W.

2014-12-01

The eastern equatorial Pacific (EEP) is one of the most dynamic oceanographic regions, making it a critical area for understanding past climate change. Despite this, there remains uncertainty on the climatic evolution of the EEP through the last glacial period. According to the ocean dynamical thermostat theory, warming (cooling) of the tropical Pacific Ocean may lead to a more La Niña (El Niño)-like mean state due to zonally asymmetric heating and subsequent easterly (westerly) wind anomalies at the equator (Clement and Cane, 1999). Attempts to understand these feedbacks on millennial timescales across Marine Isotope Stage 3 (MIS 3) have proven to be fruitful in the western equatorial Pacific (WEP) (Stott et al., 2002), yet complimentary, high-resolution records from the EEP are lacking. To provide a more complete understanding of the feedback mechanisms of the dynamical thermostat across periods of abrupt climate change, we reconstruct thermocline temperature variability across MIS 3 from a sediment core located in the EEP, directly within the equatorial cold tongue upwelling region (core MV1014-02-17JC). Temperature anomalies in thermocline waters of the EEP are integrally linked to the ENSO system, with large positive and negative anomalies recorded during El Niño and La Niña events, respectively. Mg/Ca ratios in the thermocline-dwelling planktonic foraminifera Neogloboquadrina dutertrei were measured at 2 cm intervals, resulting in a temporal resolution of <200 years. Preliminary results across Interstadials 5-7 reveal warmer thermocline temperatures (an increase in Mg/Ca of .25 ± .02 mmol/mol) during periods of cooling following peak Interstadial warmth over Greenland, as seen from the NGRIP δ18O record. Thus, periods of cooling over Greenland appear to correspond to an El Niño-like mean state in the tropical Pacific, in line with predictions of an ocean dynamical thermostat. Interestingly, Heinrich Event 3 corresponds to cooler thermocline temperatures, suggesting a different forcing mechanism of tropical Pacific mean state variability across Heinrich Events. The record will be extended back to 80 kyr BP, and we will also measure Globigerinoides ruber Mg/Ca ratios across MIS 3 to calculate the zonal E-W sea surface temperature gradient using published records from the WEP.

Projecting future grassland performance in the Greater Platte River Basin to assess sustainability for potential biofuel feedstock areas

NASA Astrophysics Data System (ADS)

Gu, Y.; Wylie, B. K.; Phuyal, K.

2012-12-01

In previous studies, we used vegetation condition information from archival records of satellite data (i.e., 10-year time series of Normalized Difference Vegetation Index (NDVI) data), site geophysical and biophysical features (e.g., elevation, slope and aspect, and soils), and weather and climate drivers to build ecosystem performance (EP) models to dynamically monitor EP (DMEP) in the Greater Platte River Basin (GPRB). Ecosystem performance is a surrogate approach for measuring ecosystem productivity. We estimated ecosystem site potentials (i.e., long-term ecosystem productivities), weather-based expected EP (EEP), and rangeland conditions based on these EP models. Validation of the EP results using ground observations (e.g., percentage of bare soil, LANDFIRE maps, stocking rate, and crop yield data) demonstrated the reliability of these EP models. We used this DMEP method to identify grasslands that are potentially suitable for cellulosic biofuel feedstock (e.g., switchgrass) development in the GPRB. The objectives of this study are to (1) project the future grassland EP; (2) assess the changes and trends of the future EP; and (3) examine the future sustainability of the identified biofuel feedstock areas in the GPRB. We used the EP models and future climate projections to estimate future (e.g., 2050 and 2099) climate-based projections of grassland performance in the GPRB. The future climate data were derived from the National Center for Atmospheric Research (NCAR) Community Climate System Model 3.0 (CCSM3) "SRES A1B" (a "middle" emissions path) obtained from the "Bias Corrected and Downscaled WCRP CMIP3 Climate Projections" archive (http://gdo-dcp.ucllnl.org/downscaled_cmip3_projections). Results show that, under climate scenario A1B, the potential biofuel feedstock areas in the more mesic Eastern part of the GPRB will remain productive in the future (the spatially averaged EPs for these areas are 3335 kg ha-1 year-1, 3355 kg ha-1 year-1, and 3341 kg ha-1 year-1 for the site potential, the 2050 EEP, and the 2099 EEP, respectively). Therefore, the identified potential biofuel feedstock areas will continue to be sustainable for future biofuel development. On the other hand, the identified non-biofuel grasslands in the drier Western part of the GPRB would be expected to stay unproductive, with a slight decline in the EP trend in the future (spatially averaged EPs are 1983 kg ha-1 year-1, 1977 kg ha-1 year-1, and 1964 kg ha-1 year-1 for the site potential, the 2050 EEP, and the 2099 EEP, respectively). Thus, these areas will continue to be unsuitable for biofuel feedstock development in the future. The resulting future grassland EEP maps can be used as a reference by land managers to assess the future sustainability and feasibility of the potential biofuel feedstock areas.

The Closure History of the Central American Seaway and its Relationship to Ocean Circulation and Climate

NASA Astrophysics Data System (ADS)

Waite, A. J.; Martin, E. E.; Lawrence, K. T.; Ladlow, C. G.; Newkirk, D.

2014-12-01

Paleoceanographic and ecologic studies suggest that gradual shoaling of the Central American Seaway (CAS) as the Isthmus of Panama rose between ~13 to 2 Ma caused a stepwise shutdown of deep, intermediate, and shallow Pacific water flow through the seaway into the Caribbean. This diminishing communication is thought to have significantly influenced surface currents, ocean circulation at depth, and ultimately regional and global climate. However, new studies of Panama's volcanic/tectonic history suggest the isthmus rose much earlier than previous estimates, calling into question many of our accepted implications for this gateway event under the 'Panama Hypothesis,' including strengthened thermohaline circulation, North Atlantic Deep Water production, increased North Atlantic temperature, and ties to Northern Hemisphere glaciation. Despite considerable research, few paleoceanographic studies have directly examined the possibility of earlier events in the closure history of the CAS and thus the precise linkages and timing are not well defined. To investigate early restricted CAS flow related to sill formation or pulsed exhumation events, we examine two sets of independent paleoceanographic reconstructions from Ocean Drilling Program sediment cores from the region. We assess the presence of Pacific waters within the Caribbean over the last 30 Ma via the Nd-isotopic composition of fish teeth from several Caribbean sites; these records point to sustained transport of Pacific waters into the Caribbean from at least 30 to 10 Ma. Further, alkenone-derived sea surface temperature (SST) reconstructions from the Eastern Equatorial Pacific (EEP) indicate the presence of consistently warm (>27 °C) waters in the EEP from ~12 to ~5 Ma, after which time SSTs at sites within the modern cold tongue begin to cool appreciably. The SST data imply that the EEP cold tongue, which some studies suggest is linked in part to the rise of the Panamanian isthmus, did not develop until after 5 Ma. Collectively, these paleoceanographic reconstructions and model outputs indicate notable communication of water between the Pacific and the Caribbean until at least 10 Ma and provide improved understanding of the sequence of events associated with the rise of the Isthmus of Panama and closure of the CAS.

The Assessment of Oral Microflora Exposed to 3% Ethanolic Extract of Brazilian Green Propolis Preparation Used for Hygiene Maintenance following Minor Oral Surgeries

PubMed Central

Morawiec, Tadeusz; Wojtyczka, Robert D.; Niedzielska, Iwona; Bubiłek-Bogacz, Anna; Wróbel, Jacek; Tanasiewicz, Marta; Wesołowski, Piotr; Król, Wojciech

2015-01-01

The aim of this study was to investigate the influence of a topically administered hygienic preparation containing a 3% ethanolic extract of Brazilian green propolis (EEP-B) on oral microflora spectrum changes in a group of patients who underwent common oral surgery procedures. Two gel samples were compared: the tested gel containing an active ingredient, that is, a 3% EEP-B (gel GA), and a placebo as the negative control (gel GC). The collection of microbiological material included 14 patients requiring surgical extraction of wisdom molars and short endosseous implant installation. Clinical examinations were carried out as follow-up, that is, baseline and after 5-6 weeks' time. During the first and subsequent assessment, swabs were taken from the mucosal surface. The number of microorganism species was found to have increased following the application of GC gel over the period of 5-6 weeks. This mainly affected Gram-positive rods and bacilli as well as Gram-negative rods. Application of the GA gel enriched with 3% EEP-B caused a profound reduction in the amount of Neisseria spp. and Bifidobacterium spp. strains. Elimination of seven species of microorganisms was observed: Streptococcus acidominimus, Streptococcus oralis, Staphylococcus epidermidis, Veillonella parvula, Bifidobacterium breve, Bifidobacterium longum, and Lactobacillus acidophilus. PMID:26380300

Elucidation of the EP defect in Diamond-Blackfan anemia by characterization and prospective isolation of human EPs.

PubMed

Iskander, Deena; Psaila, Bethan; Gerrard, Gareth; Chaidos, Aristeidis; En Foong, Hui; Harrington, Yvonne; Karnik, Leena C; Roberts, Irene; de la Fuente, Josu; Karadimitris, Anastasios

2015-04-16

Diamond-Blackfan anemia (DBA) is a disorder characterized by a selective defect in erythropoiesis. Delineation of the precise defect is hampered by a lack of markers that define cells giving rise to erythroid burst- and erythroid colony-forming unit (BFU-E and CFU-E) colonies, the clonogenic assays that quantify early and late erythroid progenitor (EEP and LEP) potential, respectively. By combining flow cytometry, cell-sorting, and single-cell clonogenic assays, we identified Lin(-)CD34(+)CD38(+)CD45RA(-)CD123(-)CD71(+)CD41a(-)CD105(-)CD36(-) bone marrow cells as EEP giving rise to BFU-E, and Lin(-)CD34(+/-)CD38(+)CD45RA(-)CD123(-)CD71(+)CD41a(-)CD105(+)CD36(+) cells as LEP giving rise to CFU-E, in a hierarchical fashion. We then applied these definitions to DBA and identified that, compared with controls, frequency, and clonogenicity of DBA, EEP and LEP are significantly decreased in transfusion-dependent but restored in corticosteroid-responsive patients. Thus, both quantitative and qualitative defects in erythroid progenitor (EP) contribute to defective erythropoiesis in DBA. Prospective isolation of defined EPs will facilitate more incisive study of normal and aberrant erythropoiesis. © 2015 by The American Society of Hematology.

Polyphenol profile by UHPLC-MS/MS, anti-glycation, antioxidant and cytotoxic activities of several samples of propolis from the northeastern semi-arid region of Brazil.

PubMed

Xavier, Jadriane de Almeida; Valentim, Iara Barros; Camatari, Fabiana O S; de Almeida, Alberto M M; Goulart, Henrique Fonseca; Ferro, Jamylle Nunes de Souza; Barreto, Emiliano de Oliveira; Cavalcanti, Bruno Coelho; Bottoli, Carla B G; Goulart, Marília Oliveira Fonseca

2017-12-01

Propolis has promising biological activities. Propolis samples from the Northeast of Bahia, Brazil - sample A from Ribeira do Pombal and B, from Tucano - were investigated, with new information regarding their biological activities. This paper describes the chemical profile, antioxidant, anti-glycation and cytotoxic activities of these propolis samples. Ethanol extracts of these propolis samples (EEP) and their fractions were analyzed to determine total phenolic content (TPC); antioxidant capacity through DPPH • , FRAP and lipid peroxidation; anti-glycation activity, by an in vitro glucose (10 mg/mL) bovine serum albumine (1 mg/mL) assay, during 7 d; cytotoxic activity on cancer (SF295, HCT-116, OVCAR-8, MDA-MB435, MX-1, MCF7, HL60, JURKAT, MOLT-4, K562, PC3, DU145) and normal cell lines (V79) at 0.04-25 μg/mL concentrations, for 72 h. The determination of primary phenols by ultra high-pressure liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) and volatile organic compounds content by gas chromatography-mass spectrometry (GC-MS) were also performed. The EEP polar fractions exhibited up to 90% protection against lipid peroxidation. The IC 50 value for anti-glycation activity of EEP was between 16.5 and 19.2 μg/mL, close to aminoguanidine (IC 50  = 7.7 μg/mL). The use of UHPLC-MS/MS and GC-MS allowed the identification of 12 bioactive phenols in the EEP and 24 volatile compounds, all already reported. The samples present good antioxidant/anti-glycation/cytotoxic activities and a plethora of biologically active compounds. These results suggest a potential role of propolis in targeting ageing and diseases associated with oxidative and carbonylic stress, aggregating value to them.

Caecal microbiota of chickens fed diets containing propolis.

PubMed

Eyng, C; Murakami, A E; Pedroso, A A; Duarte, C R A; Picoli, K P

2017-06-01

The present study aimed to evaluate the effect of different levels of ethanolic extract of propolis (EEP) and raw propolis (RP) on broiler performance and on selected bacterial groups in caecal microbiota using fluorescent in situ hybridization (FISH) measured by fluorescent activated cell sorting. Two experiments were conducted with 120 male chicks from 1 to 21 days of age for each, raised in cages and distributed in a completely randomized experimental design; there were five replicates with four birds per experimental unit and six treatments for each experiment (trial 1 - EEP - 0, 1000, 2000, 3000, 4000 and 5000 ppm and trial 2 - RP - 0, 100, 200, 300, 400 and 500 ppm). Fluorescent probes were used against the bacterial groups in caecal samples collected at 21 days of age. The data were subjected to one-way anova followed by Tukey's and regression analyses were used to assess the relationship between dietary levels of EEP or RP on performance and intestinal microbiota (p < 0.05). In the trial 1, results showed that the EEP did not cause any significant (p > 0.05) modification in the performance and caecal microbiota. In the trial 2, RP inclusion did not affect the performance but changed the bacterial composition (p < 0.05). Clostridiaceae, Gammaproteobacteria excluding Enterobacteriaceae and Lactobacillus spp. showed a quadratic response (p < 0.05), with the lowest value predicted to occur at 240 ppm, 221 ppm and 213 ppm of RP respectively. The proportion of Bacteroidaceae and Gammaproteobacteria did not differ (p > 0.05) among the experimental groups. The inclusion of ethanolic extract of propolis did not affect the performance and intestinal microbiota, whereas the supplementation of raw propolis modulates the caecal microbiota composition without any effects on chicken performance. Journal of Animal Physiology and Animal Nutrition © 2016 Blackwell Verlag GmbH.

Monitoring the status of forests and rangelands in the Western United States using ecosystem performance anomalies

USGS Publications Warehouse

Rigge, Matthew B.; Wylie, Bruce; Gu, Yingxin; Belnap, Jayne; Phuyal, Khem P.; Tieszen, Larry

2013-01-01

The effects of land management and disturbance on ecosystem performance (i.e. biomass production) are often confounded by those of weather and site potential. The current study overcomes this issue by calculating the difference between actual and expected ecosystem performance (EEP) to generate ecosystem performance anomalies (EPA). This study aims to delineate and quantify average EPA from 2000–2009 within the Greater Platte and Upper Colorado River Basins, USA. Moderate Resolution Imaging Spectroradiometer (MODIS) normalized difference vegetation index (NDVI) images averaged over the growing season (GSN) served as a proxy of actual ecosystem performance. Yearly EEP was determined with rule-based piecewise regression tree models of abiotic data (climate, soils, elevation, etc.), independently created for each land cover. EPA were calculated as the residuals of the EEP to GSN relationship, and characterized as normal performing, underperforming, and overperforming at the 90% confidence level. Validation revealed that EPA values were related to biomass production (R2 = 0.56, P = 0.02) and likely to the proportion of biomass removed by livestock in the Nebraska Sandhills. Overall, 60.6% of the study area was (normal) performing near its EEP, 3.0% was severely underperforming, 5.0% was highly overperforming, and the remainder was slightly underperforming or overperforming. Generally, disturbances such as fires, floods, and insect damage, in addition to high grazing intensity, result in a negative EPA. Conversely, mature stands and appropriate management often result in positive EPA values. This method provides information critical to land managers to evaluate the appropriateness of previous management practices and restoration efforts and quantify disturbance impacts. Results are at a scale sufficient for many of the large management units of the region and for locating areas needing further investigation. Applications of EPA data to monitoring invasive species, grazing impacts, and vulnerability to plant community shifts have been suggested by land management professionals.

Polymeric Nanoparticles of Brazilian Red Propolis Extract: Preparation, Characterization, Antioxidant and Leishmanicidal Activity.

PubMed

do Nascimento, Ticiano Gomes; da Silva, Priscilla Fonseca; Azevedo, Lais Farias; da Rocha, Louisianny Guerra; de Moraes Porto, Isabel Cristina Celerino; Lima E Moura, Túlio Flávio Accioly; Basílio-Júnior, Irinaldo Diniz; Grillo, Luciano Aparecido Meireles; Dornelas, Camila Braga; Fonseca, Eduardo Jorge da Silva; de Jesus Oliveira, Eduardo; Zhang, Alex Tong; Watson, David G

2016-12-01

The ever-increasing demand for natural products and biotechnology derived from bees and ultra-modernization of various analytical devices has facilitated the rational and planned development of biotechnology products with a focus on human health to treat chronic and neglected diseases. The aim of the present study was to prepare and characterize polymeric nanoparticles loaded with Brazilian red propolis extract and evaluate the cytotoxic activity of "multiple-constituent extract in co-delivery system" for antileishmanial therapies. The polymeric nanoparticles loaded with red propolis extract were prepared with a combination of poly-ε-caprolactone and pluronic using nanoprecipitation method and characterized by different analytical techniques, antioxidant and leishmanicidal assay. The red propolis nanoparticles in aqueous medium presented particle size (200-280 nm) in nanometric scale and zeta analysis (-20 to -26 mV) revealed stability of the nanoparticles without aggregation phenomenon during 1 month. After freeze-drying method using cryoprotectant (sodium starch glycolate), it was possible to observe particles with smooth and spherical shape and apparent size of 200 to 400 nm. Attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and thermal analysis revealed the encapsulation of the flavonoids from the red propolis extract into the polymeric matrix. Ultra performance liquid chromatography coupled with diode array detector (UPLC-DAD) identified the flavonoids liquiritigenin, pinobanksin, isoliquiritigenin, formononetin and biochanin A in ethanolic extract of propolis (EEP) and nanoparticles of red propolis extract (NRPE). The efficiency of encapsulation was determinate, and median values (75.0 %) were calculated using UPLC-DAD. 2,2-Diphenyl-1-picryhydrazyl method showed antioxidant activity to EEP and red propolis nanoparticles. Compared to negative control, EEP and NRPE exhibited leishmanicidal activity with an IC50 value of ≅38.0 μg/mL and 31.3 μg/mL, 47.2 μg/mL, 154.2μg/mL and 193.2 μg/mL for NRPE A1, NRPE A2, NRPE A3 and NRPE A4, respectively. Nanoparticles loaded with red propolis extract in co-delivery system and EEP presented cytotoxic activity on Leishmania (V.) braziliensis. Red propolis extract loaded in nanoparticles has shown to be potential candidates as intermediate products for preparation of various pharmaceutical dosage forms containing red propolis extract in the therapy against negligible diseases such as leishmaniasis. Graphical Abstract Some biochemical mechanisms of cellular debridement of Leishmania (V.) braziliensis species by the flavonoids of red propolis extract (EEP) or NRPE loaded with red propolis extract.

Conformal Antennas, Research Program Review and Workshop Held at Crystal City, Arlington, Virginia, on 15-16 April 1975

DTIC Science & Technology

1975-04-01

Vol. 62, pp. 1438-1461, November, 1947. 6. Y . Whang and R. G. Kouyoumjian: Private Commo-iication. 7. G. Hasserjian: "Currents Induced...nuiTi T ■ »■• magnetic currant along a cone oener?.ccr is given by; Mar source. where: m ^m y = angle between cone generator...i e res he r e han t he confo r mal ar r y h r ~a c. To k eep los a·rc r f vo lume to a minim m required a compac feed ~hich w s pac k a ed nearly

The beginnings of modern research on propolis in poland.

PubMed

Kuropatnicki, Andrzej K; Szliszka, Ewelina; Kłósek, Małgorzata; Król, Wojciech

2013-01-01

Propolis studies in Poland were initiated by Professor Stan Scheller in the 1960s. It was a team of Polish researchers who developed a method of introducing hydrophobic ethanol extracts of propolis (EEP) into aqueous solutions, which enabled the study of their biological properties. The studies performed in Poland showed that EEP possesses antioxidant, radioprotective, and immunostimulating properties. It was possible to demonstrate antibacterial activity of propolis on Gram-positive bacteria, virulent Mycobacterium tuberculosis, and protozoa as well as stimulating activity of aqueous extracts of propolis on proliferation of cells in vitro. Polish investigators showed that propolis stimulates regeneration of tissue, acts as antioxidant and radioprotector, has strong immunostimulative properties, affects animals' life span by extending it, and improves intellectual and life functions of the elderly.

Temperature correlations between the eastern equatorial Pacific and Antarctica over the past 230,000 years

NASA Astrophysics Data System (ADS)

Koutavas, Athanasios

2018-03-01

Tropical sea surface temperatures (SSTs) warmed and cooled in step with the Pleistocene ice age cycles, but the mechanisms are not known. It is assumed that the answer must involve radiative forcing by CO2 but SST reconstructions have been too sparse for a conclusive test. Here I present a 230,000-yr tropical SST stack from the eastern equatorial Pacific (EEP) using two new Mg/Ca reconstructions combined with three earlier ones. The EEP stack shows persistent covariation with Antarctic temperature on orbital and millennial timescales indicating tight coupling between the two regions. This coupling however cannot be explained solely by CO2 forcing because in at least one important case, the Marine Isotope Stage (MIS) 5e-5d glacial inception, both regions cooled ∼5-6.5 thousand years before CO2 decreased. More likely, their covariation was due to advection of Antarctic climate signals to the EEP by the ocean. To explain the MIS 5e-5d event and glacial inception in general the hypothesis is advanced that the cooling signal spreads globally from the Northern Hemisphere with an active ocean circulation - first from the North Atlantic to the Southern Ocean with a colder North Atlantic Deep Water, and then to the Indian and Pacific Oceans with cooler Antarctic deep and intermediate waters.

Formulation of microemulsion propolis fluoride (PF) as varnish topical agent to stop activity of teeth caries

NASA Astrophysics Data System (ADS)

Sahlan, Muhamad; Prakoso, Chandra Dwi; Darwita, Risqa Rina; Hermansyah, Heri

2017-02-01

Topical fluoride is proven to have higher efficacy in preventing dental caries with low production cost and easy to apply. The objective of this research is to formulate alternative agent topical fluoride NH4F 5% mixed with extract ethanol propolis (EEP) in the micro-emulsion system that has high stability, antimicrobial activity, and remineralization capability to arrest teeth caries activity. By using total plate count (TPC) analysis, formulation 2.7% EEP; 6,3% surfactant; and 90,9% NH4F shows good perform to inhibit cariogenic bacteria development around 78-80%. Scanning Electron Microscopy (SEM) and Energy Dispersive X-Ray (EDX) result also showed that sample successfully remineralized enamel surface. In addition, sample showed good pH, flavonoid, and polyphenol stability for 40 days.

The Beginnings of Modern Research on Propolis in Poland

PubMed Central

Kłósek, Małgorzata; Król, Wojciech

2013-01-01

Propolis studies in Poland were initiated by Professor Stan Scheller in the 1960s. It was a team of Polish researchers who developed a method of introducing hydrophobic ethanol extracts of propolis (EEP) into aqueous solutions, which enabled the study of their biological properties. The studies performed in Poland showed that EEP possesses antioxidant, radioprotective, and immunostimulating properties. It was possible to demonstrate antibacterial activity of propolis on Gram-positive bacteria, virulent Mycobacterium tuberculosis, and protozoa as well as stimulating activity of aqueous extracts of propolis on proliferation of cells in vitro. Polish investigators showed that propolis stimulates regeneration of tissue, acts as antioxidant and radioprotector, has strong immunostimulative properties, affects animals' life span by extending it, and improves intellectual and life functions of the elderly. PMID:23864903

Evidence of Enhanced Respired Carbon in Eastern Equatorial Pacific Deep-Waters over the last 30,000 years

NASA Astrophysics Data System (ADS)

Umling, N. E.; Thunell, R.

2016-12-01

Rapid decreases in glacial deep water reservoir ages have been observed in the Eastern Equatorial Pacific (EEP; this study), North Pacific (Rae et al., 2014), Southwest Pacific (Sikes et al., 2016), and North Atlantic (Skinner et al., 2013). It has been hypothesized that release of a deep ocean 14C-depleted, respired-carbon reservoir to the surface ocean and atmosphere is the most likely mechanism for the observed increases in atmospheric CO2 concentrations recorded in ice cores during the last glacial-interglacial transition (Broecker and Barker, 2007). This study examines whether oxygenation, organic carbon flux, and carbonate chemistry in the EEP deep-waters reflect an increase in respired carbon associated with recorded 14C-depletions using isotopic and trace element records from three Panama Basin cores (2,650-3,200 m water-depth). An increase in glacial deep-water respired carbon storage would result in a shift of DIC speciation towards lower carbonate ion concentrations along with deoxygenation of bottom waters. Specifically, we use the boron to calcium (B/Ca) and uranium to calcium (U/Ca) ratios of the benthic foraminifera Cibicidoides wuellerstorfi to reconstruct deep-water carbonate ion concentration (Yu and Elderfield, 2007; Raizsch et al., 2011). Additionally, bottom water oxygenation is estimated from the difference in δ13C of benthic foraminifera living in pore waters at the anoxic boundary and of those living in bottom water (Δ δ13C; Hoogakker et al., 2015, 2016), while carbon flux was assessed from the U/Ca and Cd/Ca of foraminiferal authigenic coatings.

33 CFR 146.140 - Emergency Evacuation Plan.

Code of Federal Regulations, 2013 CFR

2013-07-01

... placing the facility in operation. The OCMI reviews the EEP to determine whether all items listed in..., and environmental conditions, such as approaching hurricanes or ice floes, in which the facility or...

33 CFR 146.140 - Emergency Evacuation Plan.

Code of Federal Regulations, 2012 CFR

2012-07-01

... placing the facility in operation. The OCMI reviews the EEP to determine whether all items listed in..., and environmental conditions, such as approaching hurricanes or ice floes, in which the facility or...

33 CFR 146.140 - Emergency Evacuation Plan.

Code of Federal Regulations, 2011 CFR

2011-07-01

... placing the facility in operation. The OCMI reviews the EEP to determine whether all items listed in..., and environmental conditions, such as approaching hurricanes or ice floes, in which the facility or...

33 CFR 146.140 - Emergency Evacuation Plan.

Code of Federal Regulations, 2014 CFR

2014-07-01

... placing the facility in operation. The OCMI reviews the EEP to determine whether all items listed in..., and environmental conditions, such as approaching hurricanes or ice floes, in which the facility or...

Metric Properties of Relativistic Rotating Frames with Axial Symmetry

NASA Astrophysics Data System (ADS)

Torres, S. A.; Arenas, J. R.

2017-07-01

This abstract summarizes our poster contribution to the conference. We study the properties of an axially symmetric stationary gravitational field, by considering the spacetime properties of an uniformly rotating frame and the Einstein's Equivalence Principle (EEP). To undertake this, the weak field and slow-rotation limit of the kerr metric are determined, by making a first-order perturbation to the metric of a rotating frame. Also, we show a local connection between the effects of centrifugal and Coriolis forces with the effects of an axially symmetric stationary weak gravitational field, by calculating the geodesic equations of a free particle. It is observed that these geodesic, applying the (EEP), are locally equivalent to the geodesic equations of a free particle on a rotating frame. Furthermore, some aditional properties as the Lense-Thirring effect, the Sagnac effect, among others are studied.

A restricted proof that the weak equivalence principle implies the Einstein equivalence principle

NASA Technical Reports Server (NTRS)

Lightman, A. P.; Lee, D. L.

1973-01-01

Schiff has conjectured that the weak equivalence principle (WEP) implies the Einstein equivalence principle (EEP). A proof is presented of Schiff's conjecture, restricted to: (1) test bodies made of electromagnetically interacting point particles, that fall from rest in a static, spherically symmetric gravitational field; (2) theories of gravity within a certain broad class - a class that includes almost all complete relativistic theories that have been found in the literature, but with each theory truncated to contain only point particles plus electromagnetic and gravitational fields. The proof shows that every nonmentric theory in the class (every theory that violates EEP) must violate WEP. A formula is derived for the magnitude of the violation. It is shown that WEP is a powerful theoretical and experimental tool for constraining the manner in which gravity couples to electromagnetism in gravitation theories.

Chemical Composition and Anti-Inflammatory Effect of Ethanolic Extract of Brazilian Green Propolis on Activated J774A.1 Macrophages

PubMed Central

Kucharska, Alicja Z.; Sokół-Łętowska, Anna; Czuba, Zenon P.; Król, Wojciech

2013-01-01

The aim of this study was to investigate the chemical composition and anti-inflammatory effect of ethanolic extract of Brazilian green propolis (EEP-B) on LPS + IFN-γ or PMA stimulated J774A.1 macrophages. The identification and quantification of phenolic compounds in green propolis extract were performed using HPLC-DAD and UPLC-Q-TOF-MS methods. The cell viability was evaluated by MTT and LDH assays. The radical scavenging ability was determined using DPPH• and ABTS•+. ROS and RNS generation was analyzed by chemiluminescence. NO concentration was detected by the Griess reaction. The release of various cytokines by activated J774A.1 cells was measured in the culture supernatants using a multiplex bead array system based on xMAP technology. Artepillin C, kaempferide, and their derivatives were the main phenolics found in green propolis. At the tested concentrations, the EEP-B did not decrease the cell viability and did not cause the cytotoxicity. EEP-B exerted strong antioxidant activity and significantly inhibited the production of ROS, RNS, NO, cytokine IL-1α, IL-1β, IL-4, IL-6, IL-12p40, IL-13, TNF-α, G-CSF, GM-CSF, MCP-1, MIP-1α, MIP-1β, and RANTES in stimulated J774A.1 macrophages. Our findings provide new insights for understanding the anti-inflammatory mechanism of action of Brazilian green propolis extract and support its application in complementary and alternative medicine. PMID:23840273

A Comprehensive Program for Measurement of Military Aircraft Emissions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cheng, Mengdawn

2009-11-01

Emissions of gases and particulate matter by military aircraft were characterized inplume by 'extractive' and 'optical remote-sensing (ORS)' technologies. Non-volatile particle size distribution, number and mass concentrations were measured with good precision and reproducibly. Time-integrated particulate filter samples were collected and analyzed for smoke number, elemental composition, carbon contents, and sulfate. Observed at EEP the geometric mean diameter (as measured by the mobility diameter) generally increased as the engine power setting increased, which is consistent with downstream observations. The modal diameters at the downstream locations are larger than that at EEP at the same engine power level. The results indicatemore » that engine particles were processed by condensation, for example, leading to particle growth in-plume. Elemental analysis indicated little metals were present in the exhaust, while most of the exhaust materials in the particulate phase were carbon and sulfate (in the JP-8 fuel). CO, CO{sub 2}, NO, NO{sub 2}, SO{sub 2}, HCHO, ethylene, acetylene, propylene, and alkanes were measured. The last five species were most noticeable under engine idle condition. The levels of hydrocarbons emitted at high engine power level were generally below the detection limits. ORS techniques yielded real-time gaseous measurement, but the same techniques could not be extended directly to ultrafine particles found in all engine exhausts. The results validated sampling methodology and measurement techniques used for non-volatile particulate aircraft emissions, which also highlighted the needs for further research on sampling and measurement for volatile particulate matter and semi-volatile species in the engine exhaust especially at the low engine power setting.« less

The Confrontation between General Relativity and Experiment.

PubMed

Will, Clifford M

2006-01-01

The status of experimental tests of general relativity and of theoretical frameworks for analyzing them is reviewed. Einstein's equivalence principle (EEP) is well supported by experiments such as the Eötvös experiment, tests of special relativity, and the gravitational redshift experiment. Ongoing tests of EEP and of the inverse square law are searching for new interactions arising from unification or quantum gravity. Tests of general relativity at the post-Newtonian level have reached high precision, including the light deflection, the Shapiro time delay, the perihelion advance of Mercury, and the Nordtvedt effect in lunar motion. Gravitational wave damping has been detected in an amount that agrees with general relativity to better than half a percent using the Hulse-Taylor binary pulsar, and other binary pulsar systems have yielded other tests, especially of strong-field effects. When direct observation of gravitational radiation from astrophysical sources begins, new tests of general relativity will be possible.

The Confrontation between General Relativity and Experiment.

PubMed

Will, Clifford M

2001-01-01

The status of experimental tests of general relativity and of theoretical frameworks for analysing them are reviewed. Einstein's equivalence principle (EEP) is well supported by experiments such as the Eötvös experiment, tests of special relativity, and the gravitational redshift experiment. Future tests of EEP and of the inverse square law will search for new interactions arising from unification or quantum gravity. Tests of general relativity at the post-Newtonian level have reached high precision, including the light defl ection the Shapiro time delay, the perihelion advance of Mercury, and the Nordtvedt effect in lunar motion. Gravitational wave damping has been detected in an amount that agrees with general relativity to half a percent using the Hulse-Taylor binary pulsar, and new binary pulsar systems may yield further improvements. When direct observation of gravitational radiation from astrophysical sources begins, new tests of general relativity will be possible.

Isobaric analog resonances in (e,e'p) on $sup 90$Zr, $sup 89$Y, and $sup 88$Sr

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shoda, K.; Sugawara, M.; Saito, T.

1974-01-01

Photoproton energy and angular distributions were measured for the (e,e'p) reaction on /sup 90/Zr, /sup 89/Y and /sup 88/Sr at a number of elec tron bombarding energies. Proton groups passing through resonances are found in the energy distributions. The dependence on the residual states is studied, and it is found that a large contribution from core excitation exists in the strong E1 IAS. The configurations of these IAS are discussed with respect to the angular distributions. Cross sections of the ( gamma ,p/sub o/) reaction were extracted from the photoproton spectra. The results show a coherent T + 1 resonancemore » in good agreement with theory. The E1 IAS are compared with the results from various types of nuclear reactions. Strerigths of the IAR are found to depend on the type of reaction. (16 figures, 5 tables) (auth)« less

The Confrontation between General Relativity and Experiment.

PubMed

Will, Clifford M

2014-01-01

The status of experimental tests of general relativity and of theoretical frameworks for analyzing them is reviewed and updated. Einstein's equivalence principle (EEP) is well supported by experiments such as the Eötvös experiment, tests of local Lorentz invariance and clock experiments. Ongoing tests of EEP and of the inverse square law are searching for new interactions arising from unification or quantum gravity. Tests of general relativity at the post-Newtonian level have reached high precision, including the light deflection, the Shapiro time delay, the perihelion advance of Mercury, the Nordtvedt effect in lunar motion, and frame-dragging. Gravitational wave damping has been detected in an amount that agrees with general relativity to better than half a percent using the Hulse-Taylor binary pulsar, and a growing family of other binary pulsar systems is yielding new tests, especially of strong-field effects. Current and future tests of relativity will center on strong gravity and gravitational waves.

Asymmetric Response of the Equatorial Pacific SST to Climate Warming and Cooling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Fukai; Luo, Yiyong; Lu, Jian

The response of the equatorial Pacific Ocean to heat fluxes of equal amplitude but opposite sign is investigated using the Community Earth System Model (CESM). Results show a strong asymmetry in SST changes. In the eastern equatorial Pacific (EEP), the warming responding to the positive forcing exceeds the cooling to the negative forcing; while in the western equatorial Pacific (WEP), it is the other way around and the cooling surpasses the warming. This leads to a zonal dipole asymmetric structure, with positive values in the east and negative values in the west. A surface heat budget analysis suggests that themore » SST asymmetry is mainly resulted from the oceanic horizontal advection and vertical entrainment, with both of their linear and nonlinear components playing a role. For the linear component, its change appears to be more significant over the EEP (WEP) in the positive (negative) forcing scenario, favoring the seesaw pattern of the SST asymmetry. For the nonlinear component, its change acts to warm (cool) the EEP (WEP) in both scenarios, also favorable for the development of the SST asymmetry. Additional experiments with a slab ocean confirm the dominant role of ocean dynamical processes for this SST asymmetry. The net surface heat flux, in contrast, works to reduce the SST asymmetry through its shortwave radiation and latent heat flux components, with the former being related to the nonlinear relationship between SST and convection, and the latter being attributable to Newtonian damping and air-sea stability effects. The suppressing effect of shortwave radiation on SST asymmetry is further verified by partially coupled overriding experiments.« less

Asymmetric response of the equatorial Pacific SST to climate warming and cooling

NASA Astrophysics Data System (ADS)

Luo, Y.; Liu, F.; Lu, J.

2017-12-01

The response of the equatorial Pacific Ocean to heat fluxes of equal amplitude but opposite sign is investigated using the Community Earth System Model (CESM). Results show a strong asymmetry in SST changes. In the eastern equatorial Pacific (EEP), the warming responding to the positive forcing exceeds the cooling to the negative forcing; while in the western equatorial Pacific (WEP), it is the other way around and the cooling surpasses the warming. This leads to a zonal dipole asymmetric structure, with positive values in the east and negative values in the west. A surface heat budget analysis suggests that the SST asymmetry is mainly resulted from the oceanic horizontal advection and vertical entrainment, with both of their linear and nonlinear components playing a role. For the linear component, its change appears to be more significant over the EEP (WEP) in the positive (negative) forcing scenario, favoring the seesaw pattern of the SST asymmetry. For the nonlinear component, its change acts to warm (cool) the EEP (WEP) in both scenarios, also favorable for the development of the SST asymmetry. Additional experiments with a slab ocean confirm the dominant role of ocean dynamical processes for this SST asymmetry. The net surface heat flux, in contrast, works to reduce the SST asymmetry through its shortwave radiation and latent heat flux components, with the former being related to the nonlinear relationship between SST and convection, and the latter being attributable to Newtonian damping and air-sea stability effects. The suppressing effect of shortwave radiation on SST asymmetry is further verified by partially coupled overriding experiments.

49 CFR Appendix C to Part 236 - Safety Assurance Criteria and Processes

Code of Federal Regulations, 2011 CFR

2011-10-01

.../Programmable/Electronic Safety (E/E/P/ES) Related Systems, Parts 1-7 as follows: (A) IEC 61508-1 (1998-12) Part.... (B) IEC 61508-2 (2000-05) Part 2: Requirements for electrical/electronic/programmable electronic...

49 CFR Appendix C to Part 236 - Safety Assurance Criteria and Processes

Code of Federal Regulations, 2012 CFR

2012-10-01

.../Programmable/Electronic Safety (E/E/P/ES) Related Systems, Parts 1-7 as follows: (A) IEC 61508-1 (1998-12) Part.... (B) IEC 61508-2 (2000-05) Part 2: Requirements for electrical/electronic/programmable electronic...

49 CFR Appendix C to Part 236 - Safety Assurance Criteria and Processes

Code of Federal Regulations, 2014 CFR

2014-10-01

.../Programmable/Electronic Safety (E/E/P/ES) Related Systems, Parts 1-7 as follows: (A) IEC 61508-1 (1998-12) Part.... (B) IEC 61508-2 (2000-05) Part 2: Requirements for electrical/electronic/programmable electronic...

49 CFR Appendix C to Part 236 - Safety Assurance Criteria and Processes

Code of Federal Regulations, 2013 CFR

2013-10-01

.../Programmable/Electronic Safety (E/E/P/ES) Related Systems, Parts 1-7 as follows: (A) IEC 61508-1 (1998-12) Part.... (B) IEC 61508-2 (2000-05) Part 2: Requirements for electrical/electronic/programmable electronic...

Polymeric Nanoparticles of Brazilian Red Propolis Extract: Preparation, Characterization, Antioxidant and Leishmanicidal Activity

NASA Astrophysics Data System (ADS)

do Nascimento, Ticiano Gomes; da Silva, Priscilla Fonseca; Azevedo, Lais Farias; da Rocha, Louisianny Guerra; de Moraes Porto, Isabel Cristina Celerino; Lima e Moura, Túlio Flávio Accioly; Basílio-Júnior, Irinaldo Diniz; Grillo, Luciano Aparecido Meireles; Dornelas, Camila Braga; Fonseca, Eduardo Jorge da Silva; de Jesus Oliveira, Eduardo; Zhang, Alex Tong; Watson, David G.

2016-06-01

The ever-increasing demand for natural products and biotechnology derived from bees and ultra-modernization of various analytical devices has facilitated the rational and planned development of biotechnology products with a focus on human health to treat chronic and neglected diseases. The aim of the present study was to prepare and characterize polymeric nanoparticles loaded with Brazilian red propolis extract and evaluate the cytotoxic activity of "multiple-constituent extract in co-delivery system" for antileishmanial therapies. The polymeric nanoparticles loaded with red propolis extract were prepared with a combination of poly-ɛ-caprolactone and pluronic using nanoprecipitation method and characterized by different analytical techniques, antioxidant and leishmanicidal assay. The red propolis nanoparticles in aqueous medium presented particle size (200-280 nm) in nanometric scale and zeta analysis (-20 to -26 mV) revealed stability of the nanoparticles without aggregation phenomenon during 1 month. After freeze-drying method using cryoprotectant (sodium starch glycolate), it was possible to observe particles with smooth and spherical shape and apparent size of 200 to 400 nm. Attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and thermal analysis revealed the encapsulation of the flavonoids from the red propolis extract into the polymeric matrix. Ultra performance liquid chromatography coupled with diode array detector (UPLC-DAD) identified the flavonoids liquiritigenin, pinobanksin, isoliquiritigenin, formononetin and biochanin A in ethanolic extract of propolis (EEP) and nanoparticles of red propolis extract (NRPE). The efficiency of encapsulation was determinate, and median values (75.0 %) were calculated using UPLC-DAD. 2,2-Diphenyl-1-picryhydrazyl method showed antioxidant activity to EEP and red propolis nanoparticles. Compared to negative control, EEP and NRPE exhibited leishmanicidal activity with an IC50 value of ≅38.0 μg/mL and 31.3 μg/mL, 47.2 μg/mL, 154.2μg/mL and 193.2 μg/mL for NRPE A1, NRPE A2, NRPE A3 and NRPE A4, respectively. Nanoparticles loaded with red propolis extract in co-delivery system and EEP presented cytotoxic activity on Leishmania (V.) braziliensis. Red propolis extract loaded in nanoparticles has shown to be potential candidates as intermediate products for preparation of various pharmaceutical dosage forms containing red propolis extract in the therapy against negligible diseases such as leishmaniasis.

The effects of the Malaysian Department of Wildlife and National Parks' environmental education program on the environmental knowledge and attitudes of 13--17 year old students

NASA Astrophysics Data System (ADS)

Yusof, Ebil

The study focused on the effects of the Malaysian Department of Wildlife and National Park's (DWNP) environmental education program on the environmental knowledge and attitudes of the secondary school students. Conducted between May 11, 1998 and August 11, 1998, this study was designed to reflect three objectives: (1) to determine the effect of participation in the DWNP's environmental education program on environmental knowledge and attitudes of 13--17 year old Malaysian students, (2) to identify demographic factors that contribute to the change of environmental knowledge and attitudes, and (3) to establish base line data for future evaluation of the effectiveness of DWNP's environmental education program. The sample was comprised of 806 randomly selected students from 10 different schools, with 402 randomly assigned to the experimental grouped and 404 to the control group. Pretest and post-tests were administered at the schools. The experimental group was exposed to the Environmental Education Program (EEP) at the Environmental Education Center (EEC) at Bukit Rengit, Lanchang, Pahang, Malaysia sometime between May 14, 1998 and August 8, 1998. At the EEC, the experimental group was again divided, with half receiving the pretest and post-test, while the other half were given only the post-test. The instrument used in this study was a modification of the Children's Environmental Attitudes and Knowledge Scale (CHEAKS) developed by Leeming, et al. (1995). This instrument had sound psychometric properties suitable for this research setting, and allowed comparisons of results with previous studies. T-tests, ANOVA, and ANCOVA were used to determine group differences. Overall, secondary school students in the experimental group showed a significantly greater change in environmental knowledge than did students in the control group. Significant differences were also found on the Attitude sub-scale, with the control group exhibiting negative change in attitude, and slightly change occurring in the attitudes of the experimental group. There were no significant differences of the change in environmental knowledge and attitude across age and place of residence than did gender of the EEP participants. The trend of changes in environmental knowledge and attitude between school and EEC were shown negatively. Changes in both environmental knowledge and attitude began to increase but change in knowledge exceeded the change in attitude when measured between the pre and post-tests at the EEC. However, there was slightly increased in attitude toward environmental matters as compared to the change in environmental knowledge after the participants had been measured between the EEC and the school.

The Evolution of Deep Ocean Chemistry and Respired Carbon in the Eastern Equatorial Pacific Over the Last Deglaciation

NASA Astrophysics Data System (ADS)

de la Fuente, Maria; Calvo, Eva; Skinner, Luke; Pelejero, Carles; Evans, David; Müller, Wolfgang; Povea, Patricia; Cacho, Isabel

2017-12-01

It has been shown that the deep Eastern Equatorial Pacific (EEP) region was poorly ventilated during the Last Glacial Maximum (LGM) relative to Holocene values. This finding suggests a more efficient biological pump, which indirectly supports the idea of increased carbon storage in the deep ocean contributing to lower atmospheric CO2 during the last glacial. However, proxies related to respired carbon are needed in order to directly test this proposition. Here we present Cibicides wuellerstorfi B/Ca ratios from Ocean Drilling Program Site 1240 measured by laser ablation inductively coupled plasma mass spectrometry (LA-ICPMS) as a proxy for deep water carbonate saturation state (Δ[CO32-], and therefore [CO32-]), along with δ13C measurements. In addition, the U/Ca ratio in foraminiferal coatings has been analyzed as an indicator of oxygenation changes. Our results show lower [CO32-], δ13C, and [O2] values during the LGM, which would be consistent with higher respired carbon levels in the deep EEP driven, at least in part, by reduced deep water ventilation. However, the difference between LGM and Holocene [CO32-] observed at our site is relatively small, in accordance with other records from across the Pacific, suggesting that a "counteracting" mechanism, such as seafloor carbonate dissolution, also played a role. If so, this mechanism would have increased average ocean alkalinity, allowing even more atmospheric CO2 to be "sequestered" by the ocean. Therefore, the deep Pacific Ocean very likely stored a significant amount of atmospheric CO2 during the LGM, specifically due to a more efficient biological carbon pump and also an increase in average ocean alkalinity.

Ameliorative effect of propolis supplementation on alleviating bisphenol-A toxicity: Growth performance, biochemical variables, and oxidative stress biomarkers of Nile tilapia, Oreochromis niloticus (L.) fingerlings.

PubMed

Hamed, Heba S; Abdel-Tawwab, Mohsen

2017-11-01

Bisphenol-A (BPA) is one of the important pollutants in aquatic ecosystems and its detrimental effect on fish has a great concern. Propolis is a natural immune-stimulant that has various biological and pharmacological activities. Thus, its capability to alleviate the toxic effect of BPA on Nile tilapia, Oreochromis niloticus (L.) performance was assessed in a study based on a 2×2 factorial design with two levels of ethanolic extract of propolis (EEP) and two waterborne BPA concentrations in triplicates. Fish (33.9±0.55g) were exposed to 0.0 or 1.64μgBPA/L for 6weeks during which fish were fed on diets containing 0.0 or 9.0gEEP/kg diet. Fish performance, biochemical variables, and oxidative stress enzymes were significantly affected by propolis supplementation, BPA exposure, and their interaction. Propolis supplementation significantly improved fish growth and feed intake, which were significantly retarded by BPA exposure. Additionally, total protein, albumin, globulin, and acetylcholine esterase (AChE) decreased significantly. Meanwhile aspartate transferase (AST), alanine transferase (ALT), alkaline phosphatase (ALP), creatinine, and uric acid increased significantly with exposure to BPA. Levels of malondialdehyde (MDA) as well as superoxide dismutase (SOD) and catalase (CAT) activities increased significantly due to BPA exposure, whereas significant reductions in the activity of glutathione peroxidase (GPx) and glutathione S-transferase (GST) were also recorded compared to the control fish. It is noticed that EEP co-administration ameliorated these parameters. The present results evoked that propolis administration improves fish growth and alleviated BPA-induced toxicity. Copyright © 2017 Elsevier Inc. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bashor, B.S.

The major resources used by the Bureau of Environment, and Environmental Epidemiology (EEP) for risk assessment are: the Integrated Risk Information System (IRIS), Health and Environmental Effects Summary Table (HEAST), Agency for Toxic Substances and disease Registry (ATSDR) Toxicological Profiles, databases at the National Library of Medicine (NLM), World Health Organization (WHO) ENvironmental Criteria, and documents that the Environmental Protection Agency (EPA) has published on Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) risk assessment activities. The Risk Assessment Review has been helpful in providing information about availability of new documents or information. No systematic method has been made availablemore » to us to locate information resources. IRIS User`s Support has been helpful in making appropriate and timely referrals. Most other EPA resources were located by serendipity and persistence. The CERCLA methodology for risk assessments is being used in environmental programs, and at present, one person is responsible for all risk assessment activities in the department, but plans are underway to train one or two people from each program area. 2 figs.« less

Demographic Differences in Learner Response to Entrepreneurial Education Programmes in Pakistan

ERIC Educational Resources Information Center

Ahmed, Tariq; Chandran, V. G. R.; Klobas, Jane E.

2017-01-01

Recent research on the benefits of entrepreneurship education has tended to ignore or "control out" possible demographic differences in outcomes for entrepreneurship graduates. This paper examines demographic differences in the perceived benefits of different components of entrepreneurship education programmes (EEPs), entrepreneurial…

U.S. EPA, Pesticide Product Label, LEMON FRESH, 09/25/1985

EPA Pesticide Factsheets

2011-04-21

... _e_c_a_~_~1~0? r'L ~t_at ~~_~~_!.~ ~~ldrd to Hu~_a~.'l_~_~~_ d5?~esJi£~~~~als DANGER ~eep Out of Reach of Children, Corrosive Causes ...

Evolution of the El Nino-Southern Oscillation in the late Holocene and insolation driven change in the tropical annual SST cycle

NASA Astrophysics Data System (ADS)

Loubere, Paul; Creamer, Winifred; Haas, Jonathan

2013-01-01

South American lake sediment records indicate that El Nino events in the eastern equatorial Pacific (EEP) became more frequent after 3000 calendar years BP. The reason for this evolution of ENSO behavior remains in question. An important trigger for ocean-atmosphere state switching in the tropical ocean is the annual cycle of sea surface temperature south of the equator along the margin of South America. This annual cycle can be reconstructed from the oxygen isotope records of the surf clam Mesodesma donacium. We provide evidence that these isotope records, as preserved in archeological deposits in coastal central Peru, reflect seasonal paleo-SST. We find that the annual SST cycle in the eastern equatorial Pacific became larger over the 4500-2500 calendar year BP interval. This is consistent with increased ENSO variability. The magnification of the annual SST cycle can be attributed to changing insolation, indicating that ENSO is sensitive to the intensity and seasonal timing of solar heating of the southern EEP.

Synchronous deglacial thermocline and deep-water ventilation in the eastern equatorial Pacific

PubMed Central

Umling, Natalie E.; Thunell, Robert C.

2017-01-01

The deep ocean is most likely the primary source of the radiocarbon-depleted CO2 released to the atmosphere during the last deglaciation. While there are well-documented millennial scale Δ14C changes during the most recent deglaciation, most marine records lack the resolution needed to identify more rapid ventilation events. Furthermore, potential age model problems with marine Δ14C records may obscure our understanding of the phase relationship between inter-ocean ventilation changes. Here we reconstruct changes in deep water and thermocline radiocarbon content over the last deglaciation in the eastern equatorial Pacific (EEP) using benthic and planktonic foraminiferal 14C. Our records demonstrate that ventilation of EEP thermocline and deep waters occurred synchronously during the last deglaciation. In addition, both gradual and rapid deglacial radiocarbon changes in these Pacific records are coeval with changes in the Atlantic records. This in-phase behaviour suggests that the Southern Ocean overturning was the dominant driver of changes in the Atlantic and Pacific ventilation during deglaciation. PMID:28112161

The evolution of the equatorial thermocline and the early Pliocene El Padre mean state

NASA Astrophysics Data System (ADS)

Ford, Heather L.; Ravelo, A. Christina; Dekens, Petra S.; LaRiviere, Jonathan P.; Wara, Michael W.

2015-06-01

The tropical Pacific thermocline strength, depth, and tilt are critical to tropical mean state and variability. During the early Pliocene (~3.5 to 4.5 Ma), the Eastern Equatorial Pacific (EEP) thermocline was deeper and the cold tongue was warmer than today, which resulted in a mean state with a reduced zonal sea surface temperature gradient or El Padre. However, it is unclear whether the deep thermocline was a local feature of the EEP or a basin-wide condition with global implications. Our measurements of Mg/Ca of Globorotalia tumida in a western equatorial Pacific site indicate Pliocene subsurface temperatures warmer than today; thus, El Padre included a basin-wide thermocline that was relatively warm, deep, and weakly tilted. At ~4 Ma, thermocline steepening was coupled to cooling of the cold tongue. Since ~4 Ma, the basin-wide thermocline cooled/shoaled gradually, with implications for thermocline feedbacks in tropical dynamics and the interpretation of TEX86-derived temperatures.

Quantum test of the equivalence principle for atoms in coherent superposition of internal energy states

PubMed Central

Rosi, G.; D'Amico, G.; Cacciapuoti, L.; Sorrentino, F.; Prevedelli, M.; Zych, M.; Brukner, Č.; Tino, G. M.

2017-01-01

The Einstein equivalence principle (EEP) has a central role in the understanding of gravity and space–time. In its weak form, or weak equivalence principle (WEP), it directly implies equivalence between inertial and gravitational mass. Verifying this principle in a regime where the relevant properties of the test body must be described by quantum theory has profound implications. Here we report on a novel WEP test for atoms: a Bragg atom interferometer in a gravity gradiometer configuration compares the free fall of rubidium atoms prepared in two hyperfine states and in their coherent superposition. The use of the superposition state allows testing genuine quantum aspects of EEP with no classical analogue, which have remained completely unexplored so far. In addition, we measure the Eötvös ratio of atoms in two hyperfine levels with relative uncertainty in the low 10−9, improving previous results by almost two orders of magnitude. PMID:28569742

The Shifting Landscape of Ratepayer-Funded Energy Efficiency in the U.S.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barbose, Galen L; Goldman, Charles; Schlegel, Jeff

Over the last two decades, utility ratepayer funding for energy efficiency programs - and the associated energy savings - has seen both booms and busts. Currently, about 35 states implement ratepayer-funded energy efficiency programs, with a total U.S. budget of $3.1 billion in 2008, approximately 80% of which is concentrated in just ten states (CEE 2008).2 However, a proliferation of new state-level policies enacted over the past several years suggests that the next decade may see a dramatic and sustained increase in overall funding levels, and a fundamental re-drawing of the energy efficiency map. These new state energy efficiency policiesmore » reflect a variety of concerns, including the increasing cost and siting challenges of building new generation and transmission, fuel cost and supply risks, and the potential cost of future carbon regulations. Within the past three years, for example, eleven states have adopted energy efficiency portfolio (or resource) standards (EEPS or EERS) that establish specific long-term savings targets that utilities are obligated to meet, and at least three other states are currently considering the same. A growing number of states have recently established laws requiring utilities to acquire all available cost-effective energy efficiency. Regulators in several Western states have also recently revised integrated resource planning (IRP) and demand-side management (DSM) planning rules to require more robust analysis of the resource potential and benefits of energy efficiency, which has resulted in increased savings targets for their energy efficiency portfolios (Hopper et al. 2008). Finally, regulators and utilities in many states are beginning to look more closely at regulatory incentive mechanisms to better align utility financial interests with improvements in customer energy efficiency. We examined energy efficiency policies on the books or in the pipeline in all 50 states, along with recent IRPs and DSM plans, and developed low, medium and high projections of future energy efficiency spending and savings. Depending on how aggressively and effectively states implement these policies, we estimate that spending on ratepayer-funded energy efficiency could increase from $3.1 billion in 2008 to more than $12 billion (nominal dollars) per year by 2020 in our high case, a growth rate in spending of about 12% per year. Annual electricity savings nationally could triple from an estimated 0.3% of retail electricity sales in 2008 to 0.9% of retail electricity sales in 2020. In the low and medium scenarios, ratepayer funding for electric and gas energy efficiency in the U.S. would increase to $5.4 and $7.5 billion, respectively, by 2020. What are the implications of such a scale-up of ratepayer-funded energy efficiency activity for national energy policy, such as a national EEPS or future carbon regulations? Can a ramp-up of this scale be achieved, and what practical constraints might slow these efforts? This paper addresses these questions by first providing an overview of recent trends in state policies pertaining to ratepayer-funded energy efficiency programs in the U.S. The paper then presents our set of projections of future spending and savings from such programs, highlighting key themes. Projected energy savings are compared to what might be required under a future national EEPS (or broader clean energy standard that includes energy efficiency), in order to gauge the potential incremental impact of such policies. In addition, the carbon emission reductions associated with our projection of energy savings from ratepayer-funded programs is compared to the total emission reductions that might be required under the American Clean Energy and Security Act of 2009 (aka, the Waxman-Markey bill), which was passed by the U.S. House of Representatives in June 2009 and would establish a cap on total greenhouse gas emission for many sectors of the U.S. economy. Last, the paper discusses some of the major obstacles and challenges that states and program administrators may face over the coming decade, as they seek to dramatically ramp-up ratepayer-funded energy efficiency program activity, as projected.« less

Demography as Destiny?

ERIC Educational Resources Information Center

Ladner, Matthew; Lips, Dan

2009-01-01

A major debate among education reformers over how best to reduce the achievement gap broke out during the 2008 presidential campaign. Most advocates on both sides backed Barack Obama, but they urged him to pursue different policies. The Education Equality Project (EEP) supported a continuation of accountability and other school-focused reforms.…

Illuminating the Black Box of Entrepreneurship Education Programmes: Part 2

ERIC Educational Resources Information Center

Maritz, Alex

2017-01-01

Purpose: The purpose of this paper is to provide a justified, legitimate and validated model on entrepreneurship education programmes (EEPs), by combining recent research and scholarship in leading edge entrepreneurship education (EE). Design/methodology/approach: A systematic literature review of recent EE research and scholarship is followed by…

A Video Transmission System for Severely Degraded Channels

DTIC Science & Technology

2006-07-01

rate compatible punctured convolutional codes (RCPC) . By separating the SPIHT bitstream...June 2000. 149 [170] J. Hagenauer, Rate - compatible punctured convolutional codes (RCPC codes ) and their applications, IEEE Transactions on...Farvardin [160] used rate compatible convolutional codes . They noticed that for some transmission rates , one of their EEP schemes, which may

U.S. EPA, Pesticide Product Label, AATREX 4L HERBICIDE, 03/27/1986

EPA Pesticide Factsheets

2011-04-13

... "d-~f'\\! I "'''.d' ill' (,fes,"1 ill iI[:';'Cill,Of' fel"'l:> .. e t"e"" .. ·t" iI s .. eep t>.() . 0' O!"ef 5",: .. 0 '...,p .• I"'1."! ., ilpp"cat.c'" Of ... s •• " .op,o .. ed CO"laC! ...

Ecological Engineering Practices for the Reduction of Excess Nitrogen in Human-Influenced Landscapes: A Guide for Watershed Managers

EPA Science Inventory

Excess nitrogen (N) in freshwater systems, estuaries, and coastal areas has well-documented deleterious effects on ecosystems. Ecological engineering practices (EEPs) may be effective at decreasing nonpoint source N leaching to surface and groundwater. However, few studies have s...

Moving beyond Traditional Measures of Entrepreneurial Intentions in a Study among Life-Sciences Students in the Netherlands

ERIC Educational Resources Information Center

Lans, Thomas; Gulikers, Judith; Batterink, Maarten

2010-01-01

The rationale behind this study is that entrepreneurship education programmes (EEP) in post-compulsory education mainly address entrepreneurial intentions, instead of actual entrepreneurial behaviour, and that students, compared to practicing entrepreneurs, might have a wide range of entrepreneurial intentions when entering such a programme. The…

Antibacterial effect of propolis derived from tribal region on Streptococcus mutans and Lactobacillus acidophilus: An in vitro study.

PubMed

Airen, Bhuvnesh; Sarkar, Priyanka Airen; Tomar, Urvashi; Bishen, Kundendu Arya

2018-01-01

The study aimed at investigating in vitro antimicrobial activity of ethanolic extract of propolis (EEP) and water extract of propolis against two main cariogenic oral pathogens: Streptococcus mutans and Lactobacillus acidophilus. Propolis was obtained from beehives in the Jhabua region of India. Ethanolic and water extracts were prepared at concentrations of 5% and 20% weight/volume (w/v). To support the results, a positive control (chlorhexidine 0.2%) and a negative control (distilled water) were used. S. mutans was cultured on brain-heart infusion agar and L. acidophilus was cultured on De Man, Rogosa, and Sharpe agar. The results showed that at concentrations of 5% and 20%, EEP was effective against S. mutans and L. acidophilus. However, at similar concentrations, water extract was effective only against L. acidophilus. The highest activity was shown by chlorhexidine (0.2%) with mean zones of inhibition of 13.9 mm and 15.1 mm against S. mutans and L. acidophilus, respectively. It can be concluded that the propolis extracted from tribal regions of Jhabua possesses antibacterial efficacy against S. mutans and L. acidophilus.

Enantiomeric separation of pharmaceutically important drug intermediates using a Metagenomic lipase and optimization of its large scale production.

PubMed

Kumar, Rakesh; Banoth, Linga; Banerjee, Uttam Chand; Kaur, Jagdeep

2017-02-01

In the present study, efficient enzymatic methods were developed using a recombinant metagenomic lipase (LipR1) for the synthesis of corresponding esters by the transesterification of five different pharmaceutically important secondary alcohols. The recombinant lipase (specific activity=87m6U/mg) showed maximum conversion in presence of ionic liquid with Naphthyl-ethanol (eeP=99%), Indanol and Methyl-4 pyridine methanol (eeS of 98% and 99%) respectively in 1h. Vinyl acetate was found as suitable acyl donor in transesterification reactions. It was interesting to observe that maximum eeP of 85% was observed in just 15min with 1-indanol. As this enzyme demonstrated pharmaceutical applications, attempts were made to scale up the enzyme production on a pilot scale in a 5litre bioreactor. Different physical parameters affecting enzyme production and biomass concentration such as agitation rate, aeration rate and inoculum concentration were evaluated. Maximum lipase activity of 8463U/ml was obtained at 7h of cultivation at 1 lpm, 300rpm and 1.5% inoculum. Copyright © 2016 Elsevier B.V. All rights reserved.

Changes in Eastern Equatorial Pacific Thermocline Structure across the Last Deglaciation: Evidence from the Carnegie Ridge

NASA Astrophysics Data System (ADS)

Glaubke, R.; Schmidt, M. W.; Warner, L.; Hertzberg, J. E.; Marcantonio, F.; Bianchi, T. S.

2017-12-01

The eastern equatorial Pacific (EEP) is an important climatological region given its influence in the modulation of the El Niño - Southern Oscillation (ENSO). The current climatic mean state of the EEP is characterized by cool sea surface temperatures (SST) and a strong, shallow thermocline. Nevertheless, there remains significant uncertainty about past changes in tropical Pacific climate and how ENSO variability relates to the millennial-scale climate events of the last deglaciation. Here, we will present 21 kyrs of Mg/Ca paleotemperature data from the surface-dwelling foraminifera Globigerinoides ruber and the thermocline-dwelling foraminifera Neogloboquadrina dutertrei collected from piston core MV1014-02-17JC (00° 10.83'S, 85° 52.00'W; 2846 m depth) on the Carnegie Ridge. Initial results reveal a 1.3°C warming of the surface ocean from the early-Holocene until 6 kyrs, a trend present in other EEP SST reconstructions (Pena et al., 2008; Timmerman et al., 2014; Lea et al., 2000). The surface ocean subsequently cools from 6 kyrs and reaches present-day temperatures by 3.5 kyrs. The subsurface reveals a nearly monotonic cooling of 1.8°C from 10.8 kyrs to the present day, which suggest a gradual shoaling of the thermocline across the Holocene. Furthermore, an increase in the vertical temperature gradient occurs from the late- to mid-Holocene, with the sharpest temperature difference centered at 6 kyrs, coincident with the mid-Holocene peak in SSTs. Taken together, these data suggest a gradual shoaling of the thermocline across the Holocene, with the variations in SST primarily governing the intensity of the vertical temperature gradient. Future work includes extending this record back to the last glacial maximum (LGM) to assess tropical Pacific mean state change across the abrupt climate events that characterized the last deglaciation.

78 FR 769 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-04

...., ABM Janitorial, etc. 82,185A EEP Quality Group, Inc., East Syracuse, NY... November 27, 2011. Working... section 222 has not been met. TA-W No. Subject firm Location Impact date 81,885 NCO Financial Systems... Systems (PPS), IWS, DDO, ISB, IPS. 82,133 Hewlett-Packard Company, Vancouver, WA. Printing and Personal...

U.S. EPA, Pesticide Product Label, WORKHOURSE SAPSTAIN AND MOLD CONTROL PRODUCT, 02/19/2008

EPA Pesticide Factsheets

2011-04-21

... ' the .R,~lstrat~~C;~t:'ISlori prior., t9,,4!le ,0f.me!~~~U,,'cornrr'erc~. ,In a~¥ cOir~~r&rdenc~i~n ttils'product alw.aY,Sr~f!ilr,to~~,;~eE;P~~~ . 'y ", ...

Should non-citizens have access to publicly funded health care?: a study of public attitudes and their affecting factors.

PubMed

Sun, L-Y; Lee, E-W; Zahra, A; Park, J-H

2015-09-01

To analyse public attitudes towards access for non-citizens to publicly funded health care and to assess the factors that affect such attitudes. Cross-sectional study. Data from 29 countries were used for a multilevel regression, and data from four countries (United States, Sweden, Philippines, and Korea) were used for a linear regression. The data were collected from the International Social Survey Program (ISSP), the World Bank, the Organization for Economic Cooperation and Development (OECD), and the United Nations. The dependent variable was considered to be agreement for non-citizen access to publicly funded health care. The independent variables included: the gross national income (GNI), the gross national income coefficient (GINI), sex, age, education, household income, employment, health insurance, self-related health status, chronic illness, percent having insurance, percent having public insurance, percent employed, percent migrants, percent of health expenditure of the total gross domestic product (GDP), and percent of social expenditure of the total GDP. Egalitarianism for education policy (EEP), egalitarianism for health policy (EHP), and willingness to contribute to an egalitarian health policy (WCHP) were also examined. In the countries surveyed, more than half of the citizens agreed that non-citizens should have access to publicly funded health care. Agreement with that statement had a negative trend with respect to the GNI. The percent having public insurance and WCHP had a significantly positive association with agreement while the percent of those with insurance had a negative relationship. In the USA, household income, EHP, and WCHP were positively associated with agreement, while females were inversely associated with agreement. In Sweden, having health insurance had an inverse association to agreement while females, postsecondary education, health insurance coverage, and WCHP were positively associated with agreement. In the Philippines, household income, EEP, and EHP had significant negative associations with agreement while WCHP had a positive relationship. In Korea, household income and self-rated health status were positively associated with agreement, while postsecondary education had a negative association. Public attitudes towards allowing non-citizens to have access to publicly funded health care present high levels of variation, even among developed countries or countries with similar GDPs. The specific socio-economic conditions within a country and an individual's own social, demographic, and economic background can have different effects on the individual's attitudes towards non-citizens. On a global level, coverage of public health insurance plays an important role for enhancing the public's positive attitudes towards non-citizens' access to publicly funded health care. On a national level, health care policies tailored toward non-citizens based on the specific situation of each country and region are necessary. Copyright © 2015 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

GARFIELD-NGS: Genomic vARiants FIltering by dEep Learning moDels in NGS.

PubMed

Ravasio, Viola; Ritelli, Marco; Legati, Andrea; Giacopuzzi, Edoardo

2018-04-14

Exome sequencing approach is extensively used in research and diagnostic laboratories to discover pathological variants and study genetic architecture of human diseases. However, a significant proportion of identified genetic variants are actually false positive calls, and this pose serious challenges for variants interpretation. Here, we propose a new tool named GARFIELD-NGS (Genomic vARiants FIltering by dEep Learning moDels in NGS), which rely on deep learning models to dissect false and true variants in exome sequencing experiments performed with Illumina or ION platforms. GARFIELD-NGS showed strong performances for both SNP and INDEL variants (AUC 0.71 - 0.98) and outperformed established hard filters. The method is robust also at low coverage down to 30X and can be applied on data generated with the recent Illumina two-colour chemistry. GARFIELD-NGS processes standard VCF file and produces a regular VCF output. Thus, it can be easily integrated in existing analysis pipeline, allowing application of different thresholds based on desired level of sensitivity and specificity. GARFIELD-NGS available at https://github.com/gedoardo83/GARFIELD-NGS. edoardo.giacopuzzi@unibs.it. Supplementary data are available at Bioinformatics online.

Emissions of Volatile Particulate Components from Turboshaft Engines running JP-8 and Fischer-Tropsch Fuels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cheng, Mengdawn; Corporan, E.; DeWitt, M.

2009-01-01

Rotating-wing aircraft or helicopters are heavily used by the US military and also a wide range of commercial applications around the world, but emissions data for this class of engines are limited. In this study, we focus on emissions from T700-GE-700 and T700-GE-701C engines; T700 engine was run with military JP-8 and T701C run with both JP-8 and Fischer-Tropsch (FT) fuels. Each engine was run at three engine power settings from the idle to maximum power in sequence. Exhaust particles measured at the engine exhaust plane (EEP) have a peak mobility diameter less than 50nm in all engine power settings.more » At a 4-m downstream location, sulfate/sulfur measurements indicate all particulate sulfur exists practically as sulfate, and the particulate sulfur and sulfate contents increased as the engine power increased. The conversion of sulfur to sulfate was found not to be dependent on engine power setting. Analysis also showed that conversion of sulfur to sulfate was not by the adsorption of sulfur dioxide gas on the soot particles and then subsequently oxidized to form sulfate, but by gas-phase conversion of SO2 via OH or O then subsequently forming H2SO4 and condensing on soot particles. Without the sulfur and aromatic components, use of the FT fuel led to significant reduction of soot emissions as compared to that of the JP-8 fuel producing less number of particles than that of the JP-8 fuel; however, the FT fuel produced much higher number concentrations of particles smaller than 7nm than that of JP-8 in all engine power settings. This indicates non-aromatics components in the FT fuel could have contributed to the enhancement of emissions of particles smaller than 7nm. These small particles are volatile, not observed at the EEP, and may be important in playing a role for the formation of secondary particles in the atmosphere or serving as a site for effective cloud nuclei condensation to occur.« less

Changes in sea-surface conditions in the Equatorial Pacific during the middle Miocene-Pliocene (IODP Site 1338)

NASA Astrophysics Data System (ADS)

Rousselle, Gabrielle; Beltran, Catherine; Sicre, Marie-Alexandrine; Raffi, Isabella; De Rafélis, Marc

2013-04-01

The modern Equatorial Pacific setting is progressively developed during the Miocene and the Pliocene, with a gradual closure of the Central American Seaway (CAS) and the gradual constriction of the Indonesian seaway. In parallel, the Earth experienced a climatic transition from the mid-Miocene warm period to the modern "ice-house" climate with the growth of the Antarctic Ice-sheet (~ 13.9 Ma) and the appearance of large Northern Hemisphere Glaciations (NHG) (~ 3 Ma). In order to study the evolution of the Eastern equatorial Pacific (EEP) during the last 14 Myrs, we present here the Mio-Pliocene alkenone-derived curve, combined with the oxygen stable isotopes record of bulk carbonate (δ18Obulk) and calcareous nannofossils dominated fractions (δ18ONoelaerhabdaceae), from IODP Site 1338. The originality of this work lies in that the calcareous nannofossils species that are concentrated in the fine fractions belong to the same family to the alkenone producers. We are then able to compare an organic and an inorganic record from the same producer. Our data and those available from other sites of the same area show the extension of a cold tongue during the Early Pliocene (4.4-3.6 Ma). Indeed, our data suggest a shallowing of the thermocline in the EEP, between 6.8 and 6 Ma, and its shoaling between 4.8 and 4.0 Ma accompanying a sea surface cooling. Then, the timing of the thermocline shoaling does not agree with the idea that NHG initiated the Pliocene climate transition. SST and δ18ONoelaerhabdaceae time-series indicate periods of significant salinity variations. Then, comparison with the δ18OBenthic curve from sediment cores of the Equatorial Pacific Ocean allow us to distinguish between global changes and local salinity variations in the EEP, with a freshening between 11.5 and 10 Ma, and between 6.8 and 6 Ma. A pCO2 reconstruction based on δ13C of alkenone at site 1338 is currently measured and will eventually be presented, as well as TEX86 measurements in order to compare with the alkenone-based SST.

Comparison of bee products based on assays of antioxidant capacities.

PubMed

Nakajima, Yoshimi; Tsuruma, Kazuhiro; Shimazawa, Masamitsu; Mishima, Satoshi; Hara, Hideaki

2009-02-26

Bee products (including propolis, royal jelly, and bee pollen) are popular, traditional health foods. We compared antioxidant effects among water and ethanol extracts of Brazilian green propolis (WEP or EEP), its main constituents, water-soluble royal jelly (RJ), and an ethanol extract of bee pollen. The hydrogen peroxide (H2O2)-, superoxide anion (O2.-)-, and hydroxyl radical (HO.)- scavenging capacities of bee products were measured using antioxidant capacity assays that employed the reactive oxygen species (ROS)-sensitive probe 5-(and-6)-chloromethyl-2',7'-dichlorodihydrofluorescein diacetate, acetyl ester (CM-H2DCFDA) or aminophenyl fluorescein (APF). The rank order of antioxidant potencies was as follows: WEP > EEP > pollen, but neither RJ nor 10-hydroxy-2-decenoic acid (10-HDA) had any effects. Concerning the main constituents of WEP, the rank order of antioxidant effects was: caffeic acid > artepillin C > drupanin, but neither baccharin nor coumaric acid had any effects. The scavenging effects of caffeic acid were as powerful as those of trolox, but stronger than those of N-acetyl cysteine (NAC) or vitamin C. On the basis of the present assays, propolis is the most powerful antioxidant of all the bee product examined, and its effect may be partly due to the various caffeic acids it contains. Pollen, too, exhibited strong antioxidant effects.

Millimeter Wave Nonreciprocal Devices.

DTIC Science & Technology

1983-01-03

measures microwave magnetic field patterns of magnetostatic waves in LPE -YIG thin films has been developed. The probe’s sensing element is either a...Morgenthaler, "Workshop on Application of Garnet and Ferrite Thin Films to Microwave Devices," Session FC, Third Joint Intermag - Magnetism and...thin films Li... millimeter waves magnetostati c waves i A TRAC" =CmE4 F*91040 eEp y mnenu -d Dfenvely by Noek n.m--) The Microwave and Quantum

Deglacial dust provenance changes in the Eastern Equatorial Pacific and implications for ITCZ movement

NASA Astrophysics Data System (ADS)

Xie, Ruifang C.; Marcantonio, Franco

2012-02-01

The provenance of eolian dust supplied to deep-sea sediments has the potential to offer insights into changes in past atmospheric circulation. Specifically, measuring temporal changes in dust provenance can shed light on changes in the mean position of the Intertropical Convergence Zone (ITCZ), a region acting as a barrier separating wind-blown material derived from northern versus southern hemisphere sources. Here we have analyzed Nd, Sr, and Pb isotope ratios in the operationally-defined detrital component extracted from deep-sea sediments in the eastern equatorial Pacific (EEP) along a meridional transect at 110°W from 3°S to 7°N (ODP Leg 138, sites 848-853). Sr isotope results show that barite Sr has a significant influence on 87Sr/86Sr isotope ratios of samples in the upwelling zone of the EEP. However, sites located >3° or more away from the equator (sites 852 and 853) are believed to not be affected by barite Sr and provide useful detrital Sr signals. 208Pb/206Pb and 207Pb/206Pb ratios in all cores fall into the Pb-isotope space of five potential dust sources (Asia, North and Central/South America, Sahara, and Australia), with no distinct isotopic fingerprinting of the dominant source(s). ɛNd values were most valuable for discerning detrital source provenance, and their values at all sites, ranging from -5.46 to -3.25, were more unradiogenic for sediments deposited during the last glacial than for those deposited during the Holocene. There are distinct latitudinal trends in the ɛNd values, with more radiogenic values further south and less radiogenic values further north, excluding site 848. This distinction holds true for both Holocene and last glacial periods. For the most southerly site, 848, we invoke, for the first time, a distinct southern hemisphere Australian source as being responsible for the unradiogenic Nd isotope ratios. Both average last glacial and Holocene ɛNd values show similar sharp gradients along the transect between 5.29°N and 2.77°N, suggesting little movement of the glacial ITCZ in the EEP. However, during the deglacial, this gradient is stronger and shifted further north between 5.29°N and 7.21°N, suggesting a more northerly, possibly stronger, deglacial ITCZ.

I-S/A AMPE (Inter-Service/Agency Automated Message Processing Exchange) Database Update User’s Manual.

DTIC Science & Technology

1987-03-31

I E.EF-C.-J I So-SUSSCR I SEP -RJLITI 4 1 So"-.LESC F Il BEP -TEF-r, I I So4-SIJSCR I EEP- POLUT 1 001---- 5 ISk-SUESEC PI E: I Si -SUE:-CP I EP-TEPtl...wartime) E-𔃾 r 3 Table 1;-l (cont) U Code Agency - Department of Defense DQ Central Security Service 3 DR Defense Contract Audit Agency DS Defense

Electron Microscopy of Intracellular Protozoa.

DTIC Science & Technology

1982-08-01

8217 COMMiM M revee u0d& N n8e1eep1 didentify by block ntmnber) Summary * During this fiscal year, in collaboration with Col. Hendricks and his ft...CLASSIFICATION OF THIS PAGEfWPen Dats EntIer.d) -% %.. SSummary During this fiscal year, in collaboration with Col. Hendricks and his associates we...Larry D. Hendricks , PhD2 , Yoshihiro Ito, PhD 1 , and Martin Jagusiak 2 C Institute of Pathology, Case Western Reserve University, Cleveland,Ohio 441061

Hemodynamic energy generated by a combined centrifugal pump with an intra-aortic balloon pump.

PubMed

Lim, Choon Hak; Son, Ho Sung; Fang, Yung Hu; Lee, Jung Joo; Baik, Kwang Je; Kim, Kyung Hyun; Kim, Bum Soo; Lee, Hye Won; Sun, Kyung

2006-01-01

We examined the pulsatility generated by an intra-aortic balloon pump/centrifugal pump (IABP/CP) combination in terms of energy equivalent pressure (EEP) and surplus hemodynamic energy (SHE). In five cardiac-arrested pigs, the outflow cannula of the CP was inserted into the ascending aorta, the inflow cannula in the right atrium. A 30-ml IABP was subsequently placed in the descending aorta. Extracorporeal circulation was maintained for 30 minutes using a pump flow of 75 ml/kg per minute by CP alone or by IABP/CP with pressure and flow measured in the right internal carotid artery. The IABP/CP combination converted the flow to pulsatile and increased pulse pressure significantly from 9.1 +/- 1.3 mm Hg to 54.9 +/- 6.1 mm Hg (p = 0.012). It also significantly increased the percent change from mean arterial pressure to EEP from 0.2 +/- 0.3% to 23.3 +/- 6.1% (p = 0.012) and SHE from 133.2 +/- 234.5 erg/cm to 20,219.8 +/- 5842.7 erg/cm3 (p = 0.012). However, no statistical difference was observed between CP and IABP/CP in terms of mean carotid artery pressure (p = NS). In a cardiac-arrested animal model, pulsatility generated by a IABP/CP combination may be effective in terms of energy equivalent pressure and surplus hemodynamic energy.

Eating when depressed, anxious, bored, or happy: Are emotional eating types associated with unique psychological and physical health correlates?

PubMed

Braden, Abby; Musher-Eizenman, Dara; Watford, Tanya; Emley, Elizabeth

2018-06-01

The majority of research on emotional eating has examined general emotional eating, to the exclusion of more distinct emotions such as boredom and positive emotions. The current study aimed to examine whether specific types of emotional eating (i.e., eating in response to depression (EE-D), anxiety/anger (EE-A), boredom (EE-B), and positive emotions (EE-P)) were related to a range of psychological (i.e., global psychological well-being, eating disorder symptoms, emotion regulation) and physical health variables. A sample of adults (n = 189) with overweight/obesity were recruited via Amazon Mechanical Turk. Participants self-reported height and weight and completed a battery of questionnaires. Correlational analyses showed that more frequent EE-D, EE-A, and EE-B were related to poorer psychological well-being, greater eating disorder symptoms, and more difficulties with emotion regulation. EE-P was not significantly related to outcome variables. In regression analyses, eating in response to depression (EE-D) was the type of emotional eating most closely related to psychological well-being, eating disorder symptoms, and emotion regulation difficulties. Exploratory analyses revealed associations between EE-D, EE-A, and EE-B and facets of emotion regulation and specific disordered eating symptoms. Findings suggest that unique patterns exist between specific types of emotional eating and psychological outcomes. Copyright © 2018 Elsevier Ltd. All rights reserved.

Activity of Brazilian propolis against Aeromonas hydrophila and its effect on Nile tilapia growth, hematological and non-specific immune response under bacterial infection.

PubMed

Orsi, Ricardo O; Santos, Vivian G Dos; Pezzato, Luiz E; Carvalho, Pedro L P F DE; Teixeira, Caroline P; Freitas, Jakeline M A; Padovani, Carlos R; Sartori, Maria M P; Barros, Margarida M

2017-01-01

The effect of the ethanolic extract of propolis (EEP) on Aeromonas hydrophila was analyzed by determination of minimum inhibitory concentration (MIC). Then, the effects of crude propolis powder (CPP) on growth, hemato-immune parameters of the Nile tilapia, as well as its effects on resistance to A. hydrophila challenge were investigated. The CPP (0.5, 1.0, 1.5, 2.0, 2.5 and 3.0%) was added to the diet of 280 Nile tilapia (50.0 ± 5.7 g fish-1). Hemato-immune parameters were analyzed before and after the bacterial challenge. Red blood cell, hematocrit, hemoglobin, mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), and hydrogen peroxide (H2O2) and nitric oxide (NO) were evaluated. The MIC of the EEP was 13% (v/v) with a bactericidal effect after 24 hours. Growth performance was significantly lower for those fish fed diets containing 2.5 and 3% of CPP compared to the control diet. Differences in CPP levels affected fish hemoglobin, neutrophils number and NO following the bacterial challenge. For others parameters no significant differences were observed. Our results show that although propolis has bactericidal properties in vitro, the addition of crude propolis powder to Nile tilapia extruded diets does not necessarily lead to an improvement of fish health.

SlpE is a calcium-dependent cytotoxic metalloprotease associated with clinical isolates of Serratia marcescens.

PubMed

Stella, Nicholas A; Callaghan, Jake D; Zhang, Liang; Brothers, Kimberly M; Kowalski, Regis P; Huang, Jean J; Thibodeau, Patrick H; Shanks, Robert M Q

Serralysin-like proteases are found in a wide variety of bacteria. These metalloproteases are frequently implicated in virulence and are members of the widely conserved RTX-toxin family. We identified a serralysin-like protease in the genome of a clinical isolate of Serratia marcescens that is highly similar to the canonical serralysin protein, PrtS. This gene was named serralysin-like protease E, SlpE, and was found in the majority (67%) of tested clinical isolates, but was absent from most tested non-clinical isolates including the insect pathogen and reference S. marcescens strain Db11. Purified recombinant SlpE exhibited calcium-dependent protease activity similar to metalloproteases PrtS and SlpB. Induction of slpE in the low-protease-producing S. marcescens strain PIC3611 highly elevated extracellular protease activity, and extracellular secretion required the lipD type 1 secretion system gene. Transcription of slpE was highly reduced in an eepR transcription factor mutant. Mutation of the slpE gene in a highly proteolytic clinical isolate reduced its protease activity, and evidence suggests that SlpE confers cytotoxicity of S. marcescens to the A549 airway carcinoma cell line. Together, these data reveal SlpE to be an EepR-regulated cytotoxic metalloprotease associated with clinical isolates of an important opportunistic pathogen. Copyright © 2017 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

Foraminifer Shell Weight and Fragmentation: A Quantitative Study of the Influence of Temperature, [CO32-] and Dissolution on Proxies of the Marine Carbonate System

NASA Astrophysics Data System (ADS)

Mekik, F.; Pourmand, A.; Ward, B. M.

2015-12-01

Quantifying the various components of the marine carbonate system is important for understanding anthropogenic ocean acidification, and the rates and magnitudes of ocean acidification/ alkalization events in Earth's past. We performed multiple statistical analyses (factor analysis, partial correlations, multiple regression analysis and independent samples t -tests) on core top data using the Globorotalia menardii fragmentation index (MFI) in 89 core tops from across the tropical Pacific, Atlantic and Indian Oceans, the fragmentation trend of four species of foraminifers (Globorotalia truncatulinoides, G. menardii, Neogloboquadrina dutertrei and Pulleniatina obliquiloculata) in the EEP, tropical Atlantic and tropical Indian Ocean core tops, and Globorotalia menardii shell weight in a suite of 25 core tops the EEP in order to isolate the effects of surface ocean parameters such as temperature and [CO32-] from dissolution in sediments. Surface ocean parameters showed no significant effect on the G. menardii fragmentation index. We found no statistically significant influence of habitat water temperature or [CO32-] on foraminifer fragmentation in any of four species. While we found a strong influence of habitat water [CO32-] on the size normalized shell weight proxy in N. dutertrei and Pulleniatina obliquiloculata in our previous work, we found a much reduced influence of [CO32-] on the shell weight of G. menardii, which is most influenced by shell dissolution.

Modernised Portuguese schools - From IAQ and thermal comfort towards energy efficiency plans

NASA Astrophysics Data System (ADS)

Pereira, Luisa Maria Dias

A major rehabilitation and refurbishment programme of secondary school buildings has been carried out in the last few years in Portugal, led by the state-owned company Parque Escolar E.P.E. (PE), known as Secondary School Buildings Modernisation Programme. This programme took into consideration renewable energy systems, mostly solar panels for domestic hot water (DHW) production. Nevertheless, with the introduction of HVAC systems in buildings that were previously naturally ventilated, an increase on energy consumption has been verified. During the first occupancy phase of new and refurbished buildings, energy and indoor climate quality (ICQ) audits are important strategies to improve the buildings’ energy use. In new buildings, the most common errors are due to poor operation and management. Schools energy management programmes often result in a list of energy efficiency measures that do not necessarily reflect occupants’ conditions or satisfaction. They are more directed to management control and comparison with benchmarks of energy use/m2 or cost/student to assess energy efficiency. In all cases, monitoring and consumption patterns are mandatory. In this context, this thesis aims at developing energy efficiency plans (EEP) for modernised Portuguese school buildings. The framework of the thesis starts with the development of an international overview of the recent research and development in the field of energy consumption in schools [searching for statistical benchmarks that could contribute to an accurate school building indicator (SBI)]. Then, based on a database provided by Parque Escolar, an energy consumption assessment of Portuguese school buildings is presented, between the pre and post intervention phases. Drawing on this procedure, eight representative modernised secondary schools were selected, geographically and climatically distributed. After, an energy audit and indoor environment quality (IEQ) monitoring is performed in this schools selection. The continuous monitoring period varied between schools, from a minimum of 48h monitoring up to three weeks, during the mid-season [spring - autumn period (excluding summer vacation) in 2013]. Air exchange rates (AER), more specifically infiltration rates, are quantified aiming at determining the current airtightness condition of the refurbished schools. A subjective IEQ assessment is also performed, focusing on occupants’ feedback, providing insight on the potential linkages between energy use and occupants’ satisfaction and comfort. The thesis builds on the current EEP panorama and practice, which is based only on cost/energy control, extending it to address the equilibrium between IEQ evaluation and occupants’ perceived conditions/preferences. This approach is applied in two schools - selected based on the previous study on energy and IEQ conditions of the eight schools. The EEP methodology starts by deepening the knowledge of each school, mostly focusing on crossing the schools occupancy schedule with systems operation [(mainly those controlled by the building management system (BMS)]. An analysis on recently updated legislation is also performed (in particular fresh air flow rates requirements). It is shown that some potential energy savings can be achieved and that IEQ conditions can be improved at very low or even negligible costs. Other considerations, namely addressing the thermal energy production systems of the schools (e.g., boilers scheduling), the lighting systems (e.g., lighting circuits) and non-controlled plug loads, are also mentioned. Based upon all these findings, a handbook of good practice is drafted for secondary school buildings in Portugal. This EEP is accompanied by a list of Energy Efficiency Measures (EEM). It is proposed that this document is headed by a School - Energy Performance Certificate (S-EPC) based on the billed energy consumption. This document suggests the establishment of the figure of the Energy Manager.

Effects of a12-week endurance exercise program on adiposity and flexibility of Nigerian perimenopausal and postmenopausal women.

PubMed

Ogwumike, O O; Arowojolu, A O; Sanya, A O

2011-12-20

Menopause is a sign of aging in the woman. Loss of ovarian function induces a reduction in resting metabolic rate, physical energy expenditure, fat-free mass and abdominal adipose tissue accumulation. Location of adipose tissue deposit in abdominal region plays an important role in occurrence of hyperlipidemia, diabetes, hypertension and atherosclerosis. Although regular participation in physical exercise have been suggested to improve adiposity and body flexibility which are important health related components of physical fitness, few published studies are available on the effect of exercise on Nigerian menopausal women. This study investigated effects of a twelve-week endurance exercise program (EEP) on central and abdominal obesity as well as flexibility of perimenopausal and postmenopausal Nigerian women. The study employed a pretest- posttest control group design comprising a sample of 175 apparently healthy, literate, sedentary women within age range 40-59 years. They were workers in state and federal establishments in Ibadan North Local Government Area of Oyo State, Nigeria. Based on history of their last menstrual period, women with regular or irregular menstrual cycle status were allocated into perimenopausal group and those who no longer menstruated into postmenopausal group. A table of random numbers was used for further allocation into perimenopausal exercise group (PEMEG, 45), postmenopausal exercise group (POMEG, 45) perimenopausal control group (PEMCG, 42) and postmenopausal control group (POMCG, 43). Waist Hip Ratio (WHR), Body Mass Index (BMI) as well as Hip and Trunk Flexibility (HTF) were evaluated at baseline and 4weekly intervals until end of 12th week. EEP consisted of a 10-station circuit of cardiovascular endurance, flexibility, coordination, abdominal and pelvic floor muscle exercises. Data were analyzed using descriptive and inferential statistics. Mean age of participants was 52.3±4.1 years, 95% C.I (51.64-52.88) years. Significant reduction occurred between baseline and end of 12th week mean values of WHR in PEMEG (0.86 ± 0.08 vs 0.71 ± 0.07)and POMEG groups (0.88± 0.06 vs0.77 ± 0.07) while significant increases were observed between baseline values and end of 12th week mean values of HTF in PEMEG (18.84 ± 4.23vs28.27± 3.82) and POMEG (19.51 ± 4.02vs25.97± 2.36) (p<0.05). Significant changes did not occur in BMI in both groups even though mean differences were observed in baseline values compared with end of 12th week mean values of these variables. In PEMCG and POMCG groups, there were no observable changes in mean values of WHR, BMI and HTF from baseline to end of study. Participation in endurance exercise program is essential for perimenopausal and postmenopausal Nigerian women for improved central and abdominal adiposity as well as flexibility.

Quasifree (e,e'p) reaction on /sup 3/He

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jans, E.; Barreau, P.; Bernheim, M.

1982-10-04

The proton momentum distribution of /sup 3/He has been determined up to momenta of 310 MeV/c by use of the reaction /sup 3/He(e,e'p). The experimental missing energy resolution, deltaE/sub m/ = 1.2 MeV, was sufficient to separate the two- and three-body breakup channels. Results for the three-body disintegration have been obtained up to missing energy values of 80 MeV. The resulting spectral function is compared with the predictions of Faddeev and variational calculations.

An Adaptive Method of Lines with Error Control for Parabolic Equations of the Reaction-Diffusion Type.

DTIC Science & Technology

1984-06-01

space discretization error . 1. I 3 1. INTRODUCTION Reaction- diffusion processes occur in many branches of biology and physical chemistry. Examples...to model reaction- diffusion phenomena. The primary goal of this adaptive method is to keep a particular norm of the space discretization error less...AD-A142 253 AN ADAPTIVE MET6 OFD LNES WITH ERROR CONTROL FOR 1 INST FOR PHYSICAL SCIENCE AND TECH. I BABUSKAAAO C7 EA OH S UMR AN UNVC EEP R

Basic Studies on Electro-Energetic Physics (EEP) Weapons Technologies

DTIC Science & Technology

2015-01-15

Po\\\\ered Microwa\\e. High Energ) Laser. Charged Particle Beams. and II) pcrsonic Rail guns . Using these representations. wargame simulations of’ arious...Projectile length = 30 in (76 cm) • Barrel length = 10 m • Muzzle velocity = 2,100 m/s To understand how such an advanced weapon compares with conventional...weaponry, it is illustrating to compare these figures with the M-1 Abrams M256 120mm gun firing a M829A1 kinetic energy round Page 5 • Muzzle

New Evidence for opening of the Black Sea; U-Pb analysis of detrital zircons and paleocurrent measurements of the Early Cretaceous turbidites

NASA Astrophysics Data System (ADS)

Akdoğan, Remziye; Okay, Aral I.; Sunal, Gürsel; Tari, Gabor; Kylander-Clark, Andrew R. C.

2015-04-01

Shelf to submarine turbidite fan deposits of the Early Cretaceous crop out over a large area along the southern coast of the Black Sea. Early Cretaceous turbidites have a thickness of over 2000 meters in the Central Pontides. The shelf of this turbidite basin, represented by shallow marine clastics and carbonates, crops out along the Black Sea coast between Zonguldak and Amasra. Paleocurrent directions in the Lower Cretaceous turbidites were measured in 90 localities using mostly flute and groove casts and to a lesser extend cross-beds. At the eastern part of the basin, the paleocurrents were from north to south. It is scattered in the west of the basin, however, the main paleocurrent directions were from the north. Detrital zircons were analyzed using LA-ICP-MS in eleven samples from the turbiditic sandstones and two samples from the shelf sandstones. Four samples are from the western part (two samples from shelf sediments), four samples from the central part and five samples from the eastern part of the Lower Cretaceous basin. 1085 of 1348 zircon analyses are concordant with rates of 95-105% and the zircon ages range between 141 ± 4 Ma (Berriasian) and 3469 ± 8 Ma (Paleoarchean). 22% of the detrital zircon ages are Paleoproterozoic, 20% Archean, 16% Carboniferous, 13% Neoproterozoic, 8% Permian, 6% Triassic, 5% Mesoproterozoic and 11% other ages. In the western part of the basin the Carboniferous zircons constitute the main population with a less dominant peak at Ordovician, Cambrian and Late Neoproterozoic. The zircons from the center of the basin show scattered distribution with dominant populations in the Triassic, Permian, Carboniferous, Silurian, Paleoproterozoic, Early Neoproterozoic-Late Mesoproterozoic, and minor peak at Late Neoarchean. On the other hand, zircons from the eastern most part of the basin, show dominant peaks in the Paleoproterozoic, Mesoarchean and Permian with minor peaks in Triassic, Carboniferous and Silurian. Anatolia and the Balkans have a late Neoproterozoic basement, whereas the East European Platform (EEP) has a Paleoproterozoic-Archean basement. The zircon and the paleocurrent data indicate that the eastern and central part of the Early Cretaceous turbidite basin was mainly fed by EEP, whereas local sources were dominant in the western part of the basin and especially fed from a crystalline basement of the Istanbul zone. This in turn indicates that the Black Sea did not form a major barrier between the Pontides and the EEP and was probably not open during the Early Cretaceous. Keywords: Central Pontides, Early Cretaceous, Paleocurrent, Provenance, U-Pb Detrital zircon.

Investigating Eastern Equatorial Pacific Export Production and Carbonate Dissolution with XRF Core Scanning at ODP Site 846 Over the Last 5 Million Years

NASA Astrophysics Data System (ADS)

Jones, C.; Robinson, R. S.

2015-12-01

Coastal and equatorial upwelling in the Eastern Equatorial Pacific (EEP) are responsible for about 10% of the ocean's total production. The deep, cold, nutrient-rich waters supplied by upwelling originate in high latitudes, linking changes at high latitudes to the tropics. The Pliocene/Pleistocene transition which started around 2.7-3 million years ago (Ma) marked a period of higher variability in biological production and sea surface temperatures dominated by glacial/interglacial cycles. In addition, secular changes in the development of both Walker and Hadley cells appear to have impacted the strength of equatorial upwelling. However, the large positive production excursions, such as those found from 1.6 to 2.2 Ma, remain only moderately well characterized and both changes in high latitude nutrient supply and regional upwelling strength are implicated. ODP Site 846 is located in the heart of the EEP upwelling cold tongue and has ideal characteristics for examining these links and excursions. We present high-resolution (~0.5 ky) X-Ray Fluorescence (XRF) chemical profiles of Ca, Si, Ba, Mn, Fe, Al, and Ti, as well as a total nitrogen (TN%) record for the last 5 million years from ODP Site 846. We use these high resolution profiles in conjunction with other regional data to assess biogeochemical processes in the EEP over the last 5 million years. CaCO3 and SiO2 are the two dominant biogenic components and account for more than 95% of the sediment. BaSO4 and the discrete TN% measurements record total productivity. MnO and Fe2O3 are redox-sensitive species and are particularly suited to tracing dissolution related to excess bottom-water metabolic processes driven by high export production at the high-alkalinity Site 846. Al2O3 and TiO2 are tracers of terrigenous input. A transition between low amplitude and high amplitude carbonate cycles occurs at 2.8 Ma, coinciding with the Pliocene/Pleistocene transition to higher amplitude glacial cycles. Notable excursions from the baseline high carbonate system occur between 3.8 and 4.2 Ma, between 1.6 and 2.2 Ma, at 0.75 Ma, and within the last 0.1 Ma. These excursions are explored, and causes include heavy contributions from productivity-driven dissolution, some extended instances of CCD-driven dissolution and shifts in overlying productivity towards diatoms.

Evaluation of Physicians’ Awareness of Pediatric Diseases in Iran

PubMed Central

Abolhassani, Hassan; Mirminachi, Babak; Daryabeigi, Maedeh; Agharahimi, Zahra; Aghamohammadi, Asghar; Rabbani, Ali; Rezaei, Nima

2014-01-01

Objective: Physicians’ awareness about pediatric health problems is very important in health system. This has not been investigated in Iran as yet. Therefore this study was conducted to characterize the knowledge of the Iranian physicians which has direct association with health status of children. Methods: One hundred and four physicians, mainly pediatric specialists (58.6%) working in the state hospitals (45.1%) were enrolled. They filled a valid and reliable questionnaire, containing 26 questions about basic and important pediatric issues before and after an educational pediatric program (EPP). Findings : Thirty nine (37.5%) physicians answered correctly more than 2/3 of all questions (passed the examination) before EPP, which increased to 42.3% after EEP. Subgroup analysis showed that the total scores of general practitioners (P=0.007) was significantly increased after the EPP. Moreover, physicians with shorter practicing time (P=0.006) and those with shorter time past graduation (P=0.01) had a significant improvement in their total scores after the program. The best scores of educational issues were documented in growth and development (16.0%; P=0.04), followed by dermatology (9.2%, P=0.04), urology (9.1%; P=0.04), and asthma and allergy (9.0%, P=0.04). Conclusion: This study revealed that there are gaps in the knowledge of professionals about the pediatric issues. PMID:25793051

Inheritance of partial resistance against Colletotrichum lindemuthianum in Phaseolus vulgaris and co-localization of quantitative trait loci with genes involved in specific resistance.

PubMed

Geffroy, V; Sévignac, M; De Oliveira, J C; Fouilloux, G; Skroch, P; Thoquet, P; Gepts, P; Langin, T; Dron, M

2000-03-01

Anthracnose, one of the most important diseases of common bean (Phaseolus vulgaris), is caused by the fungus Colletotrichum lindemuthianum. A "candidate gene" approach was used to map anthracnose resistance quantitative trait loci (QTL). Candidate genes included genes for both pathogen recognition (resistance genes and resistance gene analogs [RGAs]) and general plant defense (defense response genes). Two strains of C. lindemuthianum, identified in a world collection of 177 strains, displayed a reproducible and differential aggressiveness toward BAT93 and JaloEEP558, two parental lines of P. vulgaris representing the two major gene pools of this crop. A reliable test was developed to score partial resistance in aerial organs of the plant (stem, leaf, petiole) under controlled growth chamber conditions. BAT93 was more resistant than JaloEEP558 regardless of the organ or strain tested. With a recombinant inbred line (RIL) population derived from a cross between these two parental lines, 10 QTL were located on a genetic map harboring 143 markers, including known defense response genes, anthracnose-specific resistance genes, and RGAs. Eight of the QTL displayed isolate specificity. Two were co-localized with known defense genes (phenylalanine ammonia-lyase and hydroxyproline-rich glycoprotein) and three with anthracnose-specific resistance genes and/or RGAs. Interestingly, two QTL, with different allelic contribution, mapped on linkage group B4 in a 5.0 cM interval containing Andean and Mesoamerican specific resistance genes against C. lindemuthianum and 11 polymorphic fragments revealed with a RGA probe. The possible relationship between genes underlying specific and partial resistance is discussed.

Eastern Equatorial Pacific Dust Provenance on Deglacial Timescales

NASA Astrophysics Data System (ADS)

Xie, R.; Marcantonio, F.

2008-12-01

Changing patterns of eolian dust deposition preserved in deep-sea sediments have the potential to provide us with a better understanding of changes in past atmospheric circulation. One way in which to determine the provenance of dust in deep-sea sediments is to use radiogenic isotopic tracers which can fingerprint potential dust sources. Models (e.g., [1]) suggest that sources of dust to the Eastern Equatorial Pacific (EEP) are from areas as diverse as Asia, North, Central, and South America, and, perhaps, even Africa. Here, we investigate spatial and temporal changes in the provenance of the eolian component in the EEP by measuring Pb, Sr, and Nd isotope ratios in dust extracted from sediments along a transect at 110oW from 7oN to 3oS (ODP sites 853 - 848). In this region, although fluxes of dust were higher during the last glacial maximum (LGM) than those in the Holocene by up to 100%, the glacial flux of dust displayed a shallower meridional gradient [2]. However, it is unclear whether this shallower gradient is due to a mean southerly displacement of the Intertropical Convergence Zone (ITCZ). Most of the dust trying to pass through the ITCZ will be scavenged and rained out at the ITCZ. Along the meridional gradient, therefore, temporal variations in the Pb, Sr, and Nd isotopic fingerprints of the distinct dust sources will determine the extent to which the position of the ITCZ changes on deglacial timescales. [1] Mahowald et al., 2005, Global Biogeochemical Cycles 19, GB4025. [2] McGee et al., 2007, EPSL 257, 215-230.

Is the core top modern? Observations from the eastern equatorial Pacific

NASA Astrophysics Data System (ADS)

Mekik, Figen; Anderson, Robert

2018-04-01

A compilation of ages from 67 core tops in the eastern equatorial Pacific (EEP) does not display an easily discernible regional pattern. The ages range from 790 to over 15,000 years. The youngest core tops with the highest sediment focusing factors are located in the Panama Basin. There are weak but statistically significant inverse relationships between core top age and age-model based mass accumulation rates, bioturbation depth, linear sedimentation rate and sediment focusing factors. However, we found no statistically significant relationship between core top age and calcite dissolution in sediments or 230Th-normalized mass accumulation rates. We found evidence suggesting that greater amount of sediment focusing helps to preserve the carbonate fraction of the sediment where focusing is taking place. When focusing factors are plotted against percent calcite dissolved, we observe a strong inverse relationship, and core tops younger than 4500 years tend to occur where focusing factors are high and percent calcite dissolved values are low. Using labile organic carbon fluxes to estimate bioturbation depth in the sediments results in the observation that where bioturbation depth is shallow (<4 cm), the core top age has a strong, inverse relationship with sediment accumulation rate. We used the Globorotalia menardii Fragmentation Index (MFI) as an indicator of percent calcite dissolved in deep sea sediments. There is a distinct pattern to core top calcite dissolution in the EEP which delineates bands of high surface ocean productivity as well as the clear increase in dissolution downward on the flanks of the East Pacific Rise.

Eastern equatorial pacific productivity and related-CO2 changes since the last glacial period.

PubMed

Calvo, Eva; Pelejero, Carles; Pena, Leopoldo D; Cacho, Isabel; Logan, Graham A

2011-04-05

Understanding oceanic processes, both physical and biological, that control atmospheric CO(2) is vital for predicting their influence during the past and into the future. The Eastern Equatorial Pacific (EEP) is thought to have exerted a strong control over glacial/interglacial CO(2) variations through its link to circulation and nutrient-related changes in the Southern Ocean, the primary region of the world oceans where CO(2)-enriched deep water is upwelled to the surface ocean and comes into contact with the atmosphere. Here we present a multiproxy record of surface ocean productivity, dust inputs, and thermocline conditions for the EEP over the last 40,000 y. This allows us to detect changes in phytoplankton productivity and composition associated with increases in equatorial upwelling intensity and influence of Si-rich waters of sub-Antarctic origin. Our evidence indicates that diatoms outcompeted coccolithophores at times when the influence of Si-rich Southern Ocean intermediate waters was greatest. This shift from calcareous to noncalcareous phytoplankton would cause a lowering in atmospheric CO(2) through a reduced carbonate pump, as hypothesized by the Silicic Acid Leakage Hypothesis. However, this change does not seem to have been crucial in controlling atmospheric CO(2), as it took place during the deglaciation, when atmospheric CO(2) concentrations had already started to rise. Instead, the concomitant intensification of Antarctic upwelling brought large quantities of deep CO(2)-rich waters to the ocean surface. This process very likely dominated any biologically mediated CO(2) sequestration and probably accounts for most of the deglacial rise in atmospheric CO(2).

Database of Alluvial Radiocarbon Dates in European Russia and Siberia and its Palaeohydrological Interpretation

NASA Astrophysics Data System (ADS)

Matlakhova, Ekaterina; Panin, Andrei

2017-04-01

We collected and analyzed published radiocarbon dates from East European Plain (EEP) and Siberia to pick absolute dates on alluvial and associated deposits. After filtering unreliable dates, 1000 radiocarbon dates from EEP and 500 from Siberia were included into the database. Each date was supplied with information on geographic location and coordinates, catchment area, geomorphological position, characteristics of geological section and dated materials. Also the information about published sources was given. Documented sections refer to fluvial forms in a wide range of catchment sizes. To extract palaeohydrological signal we used two kinds of proxies: sedimentological and geomorphological. We used the following indicators of low activity: organic horizons (soil, peat) in overbank alluvium, balka bottoms and gully fans, small river palaeochannels; and the following indicators of high activity: active sedimentation on river floodplains (burial of organic horizons), balka bottoms and gully fans, erosion by flood flows on floodplains, in bottoms of balkas and gullies, river incision, big palaeochannels, channel avulsions and chute cutoffs. 
 Each date that received palaeohydrological interpretation was regarded as the indicator of a particular Local Palaeohydrological Event. Combined probability density functions of high- and low-activity dates were used to detect time intervals of different palaeohydrological status. For EEP after low fluvial activity during LGM two palaeohydrological epochs were designated: extremely high activity in the end of MIS 2 (ca. 18-11.7 ka b2k), and much lower activity in the Holocene. Within the Holocene two hierarchical levels of hydroclimatic variability were designated according to their duration and magnitude - regional palaeohydrological phases (centuries to few millennia) and regional palaeofluvial episodes (decades to few centuries). Tendency is rather clear of activity lowering in the first half and rise in the second half of the Holocene. In most cases changes of fluvial activity were most likely induced by changing amounts of spring snowmelt runoff. Most distinct correlation of temperature and hydrological regimes was found in the Late Holocene: high fluvial activity corresponded to cold climatic phases (Little Ice Age), low activity, to warm phases (Medieval Climatic Optimum, current climate warming). Correlation of changes in fluvial activity within a west-east transect over Europe revealed relatively poor correlation in the Early and Mid Holocene and much higher synchronism since 3.0 ka b2k, which may indicate increasing role of westerlies in controlling European climates in the Late Holocene. Throughout the whole Holocene, changes of fluvial activity were governed by natural climate forcing until the last few centuries when land use changes induced accelerated hillslope and gully erosion. Comparison of results over Siberia with previously published Holocene flood chronologies in Europe revealed high concordance in the last millennium (the hydrological response to the MWP and LIA climate oscillations) and less similarity in earlier time.

Resistance to Colletotrichum lindemuthianum in Phaseolus vulgaris: a case study for mapping two independent genes.

PubMed

Geffroy, Valérie; Sévignac, Mireille; Billant, Paul; Dron, Michel; Langin, Thierry

2008-02-01

Anthracnose, caused by the hemibiotrophic fungal pathogen Colletotrichum lindemuthianum is a devastating disease of common bean. Resistant cultivars are economical means for defense against this pathogen. In the present study, we mapped resistance specificities against 7 C. lindemuthianum strains of various geographical origins revealing differential reactions on BAT93 and JaloEEP558, two parents of a recombinant inbred lines (RILs) population, of Meso-american and Andean origin, respectively. Six strains revealed the segregation of two independent resistance genes. A specific numerical code calculating the LOD score in the case of two independent segregating genes (i.e. genes with duplicate effects) in a RILs population was developed in order to provide a recombination value (r) between each of the two resistance genes and the tested marker. We mapped two closely linked Andean resistance genes (Co-x, Co-w) at the end of linkage group (LG) B1 and mapped one Meso-american resistance genes (Co-u) at the end of LG B2. We also confirmed the complexity of the previously identified B4 resistance gene cluster, because four of the seven tested strains revealed a resistance specificity near Co-y from JaloEEP558 and two strains identified a resistance specificity near Co-9 from BAT93. Resistance genes found within the same cluster confer resistance to different strains of a single pathogen such as the two anthracnose specificities Co-x and Co-w clustered at the end of LG B1. Clustering of resistance specificities to multiple pathogens such as fungi (Co-u) and viruses (I) was also observed at the end of LG B2.

Cortical activation following chronic passive implantation of a wide-field suprachoroidal retinal prosthesis

NASA Astrophysics Data System (ADS)

Villalobos, Joel; Fallon, James B.; Nayagam, David A. X.; Shivdasani, Mohit N.; Luu, Chi D.; Allen, Penelope J.; Shepherd, Robert K.; Williams, Chris E.

2014-08-01

Objective. The research goal is to develop a wide-field retinal stimulating array for prosthetic vision. This study aimed at evaluating the efficacy of a suprachoroidal electrode array in evoking visual cortex activity after long term implantation. Approach. A planar silicone based electrode array (8 mm × 19 mm) was implanted into the suprachoroidal space in cats (ntotal = 10). It consisted of 20 platinum stimulating electrodes (600 μm diameter) and a trans-scleral cable terminated in a subcutaneous connector. Three months after implantation (nchronic = 6), or immediately after implantation (nacute = 4), an electrophysiological study was performed. Electrode total impedance was measured from voltage transients using 500 μs, 1 mA pulses. Electrically evoked potentials (EEPs) and multi-unit activity were recorded from the visual cortex in response to monopolar retinal stimulation. Dynamic range and cortical activation spread were calculated from the multi-unit recordings. Main results. The mean electrode total impedance in vivo following 3 months was 12.5 ± 0.3 kΩ. EEPs were recorded for 98% of the electrodes. The median evoked potential threshold was 150 nC (charge density 53 μC cm-2). The lowest stimulation thresholds were found proximal to the area centralis. Mean thresholds from multiunit activity were lower for chronic (181 ± 14 nC) compared to acute (322 ± 20 nC) electrodes (P < 0.001), but there was no difference in dynamic range or cortical activation spread. Significance. Suprachoroidal stimulation threshold was lower in chronic than acute implantation and was within safe charge limits for platinum. Electrode-tissue impedance following chronic implantation was higher, indicating the need for sufficient compliance voltage (e.g. 12.8 V for mean impedance, threshold and dynamic range). The wide-field suprachoroidal array reliably activated the retina after chronic implantation.

Reconstructing Eastern Tropical Pacific productivity across Marine Isotope Stage 3 using foraminifera faunal counts

NASA Astrophysics Data System (ADS)

McCourty, M.; Schmidt, M. W.; Glaubke, R.; Hertzberg, J. E.; Marcantonio, F.; Bianchi, T. S.

2017-12-01

The El Niño-Southern Oscillation is one of Earth's largest sources of interannual climate variability that has many global environmental impacts. Furthermore, the mean state of the tropical Pacific has the potential to change in the near future due to anthropogenic warming of the planet. In order to provide an analogue for future climate states, there is a critical need to understand how the tropical Pacific evolved across abrupt warming events in Earth's recent past. While most studies have focused on the evolution of ENSO across Marine Isotope Stages (MIS) 1 and 2, the dynamics of the tropical Pacific across the abrupt climate events of MIS 3 are still highly contentious. To develop a record of past changes in upwelling intensity in the EEP, a parameter critically linked to the tropical Pacific mean state, we quantify the faunal abundances of 6 planktonic foraminifera species from piston core MV1014-02-17JC (00° 10.83'S, 85° 52.00'W; 2846 m depth) on the Carnegie Ridge from 35 - 59 kyr. The relative abundance of Globigerina bulloides, a species associated with upwelling conditions, and 5 other planktonic foraminifera suggest an increase in water column productivity during Heinrich Event 4 and across several Dansgaard-Oeschger stadial intervals. Initial results suggest that stadials in the North Atlantic are associated with more permanent La Niña-like conditions in the EEP. However, multiple lines of evidence suggest that depth intervals in our core between 43.7 - 55.7 kyr were impacted by intense dissolution due to changes in bottom water chemistry, impacting the fidelity of our faunal count records across this interval. Future work includes extending our faunal record back to 100 kyr to include Heinrich Events 6 - 8.

Extracellular Identification of a Processed Type II ComR/ComS Pheromone of Streptococcus mutans

PubMed Central

Khan, Rabia; Rukke, Håkon V.; Ricomini Filho, Antonio Pedro; Fimland, Gunnar; Arntzen, Magnus Ø.; Thiede, Bernd

2012-01-01

The competence-stimulating peptide (CSP) and the sigX-inducing peptide (XIP) are known to induce Streptococcus mutans competence for genetic transformation. For both pheromones, direct identification of the native peptides has not been accomplished. The fact that extracellular XIP activity was recently observed in a chemically defined medium devoid of peptides, as mentioned in an accompanying paper (K. Desai, L. Mashburn-Warren, M. J. Federle, and D. A. Morrison, J. Bacteriol. 194:3774–3780, 2012), provided ideal conditions for native XIP identification. To search for the XIP identity, culture supernatants were filtered to select for peptides of less than 3 kDa, followed by C18 extraction. One peptide, not detected in the supernatant of a comS deletion mutant, was identified by tandem mass spectrometry (MS/MS) fragmentation as identical to the ComS C-terminal sequence GLDWWSL. ComS processing did not require Eep, a peptidase involved in processing or import of bacterial small hydrophobic peptides, since eep deletion had no inhibitory effect on XIP production or on synthetic XIP response. We investigated whether extracellular CSP was also produced. A reporter assay for CSP activity detection, as well as MS analysis of supernatants, revealed that CSP was not present at detectable levels. In addition, a mutant with deletion of the CSP-encoding gene comC produced endogenous XIP levels similar to those of a nondeletion mutant. The results indicate that XIP pheromone production is a natural phenomenon that may occur in the absence of natural CSP pheromone activity and that the heptapeptide GLDWWSL is an extracellular processed form of ComS, possibly the active XIP pheromone. This is the first report of direct identification of a ComR/ComS pheromone. PMID:22609914

Paleoceanography of the eastern equatorial Pacific over the past 4 million years and the geologic origins of modern Galápagos upwelling

NASA Astrophysics Data System (ADS)

Karnauskas, Kristopher B.; Mittelstaedt, Eric; Murtugudde, Raghu

2017-02-01

An isolated, volcanic archipelago at the confluence of several major ocean currents, the Galápagos Archipelago (GA) is among the most biologically diverse places on Earth. There remain many open questions concerning evolution and speciation in the GA, with the details of the geologic formation of the islands over the past millions of years representing a key source of uncertainty. Paleoceanographic sea surface temperature (SST) proxy records from the far eastern equatorial Pacific (EEP) indicate that the modern gradient of SST across the GA (the cross-island SST gradient, or CIΔT) emerged relatively abruptly ∼1.6 Ma. As the modern CI ΔT is the result of a blockage and subsequent upwelling of the Equatorial Undercurrent (EUC) by the GA, we infer from these paleoceanographic data that the modern period during which the GA is arranged such that the islands constitute a significant topographic barrier to the EUC began ∼1.6 Ma. An extensive suite of ocean circulation model experiments-new and previously published-confirms that the sign and magnitude of the change in CI ΔT captured in paleoceanographic records can be explained by the islands impinging upon the EUC. Implications for the geologic history of the Galápagos and related biogeographical questions are discussed. Additionally, these results suggest that investigations of the Pan-Pacific SST gradient (PPΔT) should use one of the available proxy sites in the EEP that is not influenced by regional, geologically forced oceanographic changes; such an analysis supports recent suggestions of a more gradual development of the modern PP ΔT over the Plio-Pleistocene.

Electron scattering from high-momentum neutrons in deuterium

NASA Astrophysics Data System (ADS)

Klimenko, A. V.; Kuhn, S. E.; Butuceanu, C.; Egiyan, K. S.; Griffioen, K. A.; Adams, G.; Ambrozewicz, P.; Anghinolfi, M.; Asryan, G.; Avakian, H.; Bagdasaryan, H.; Baillie, N.; Ball, J. P.; Baltzell, N. A.; Barrow, S.; Batourine, V.; Battaglieri, M.; Bedlinskiy, I.; Bektasoglu, M.; Bellis, M.; Benmouna, N.; Biselli, A. S.; Bouchigny, S.; Boiarinov, S.; Bradford, R.; Branford, D.; Brooks, W. K.; Bültmann, S.; Burkert, V. D.; Calarco, J. R.; Careccia, S. L.; Carman, D. S.; Cazes, A.; Chen, S.; Cole, P. L.; Coltharp, P.; Cords, D.; Corvisiero, P.; Crabb, D.; Cummings, J. P.; Dashyan, N. B.; Devita, R.; Sanctis, E. De; Degtyarenko, P. V.; Denizli, H.; Dennis, L.; Dharmawardane, K. V.; Djalali, C.; Dodge, G. E.; Donnelly, J.; Doughty, D.; Dugger, M.; Dytman, S.; Dzyubak, O. P.; Egiyan, H.; Elouadrhiri, L.; Eugenio, P.; Fatemi, R.; Fedotov, G.; Fersch, R. G.; Feuerbach, R. J.; Funsten, H.; Garçon, M.; Gavalian, G.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Goetz, J. T.; Gonenc, A.; Gordon, C. I. O.; Gothe, R. W.; Guidal, M.; Guillo, M.; Guler, N.; Guo, L.; Gyurjyan, V.; Hadjidakis, C.; Hakobyan, R. S.; Hardie, J.; Hersman, F. W.; Hicks, K.; Hleiqawi, I.; Holtrop, M.; Hyde-Wright, C. E.; Ilieva, Y.; Ireland, D. G.; Ishkhanov, B. S.; Ito, M. M.; Jenkins, D.; Jo, H. S.; Joo, K.; Juengst, H. G.; Kellie, J. D.; Khandaker, M.; Kim, W.; Klein, A.; Klein, F. J.; Kossov, M.; Kramer, L. H.; Kubarovsky, V.; Kuhn, J.; Kuleshov, S. V.; Lachniet, J.; Laget, J. M.; Langheinrich, J.; Lawrence, D.; Li, Ji; Livingston, K.; McAleer, S.; McKinnon, B.; McNabb, J. W. C.; Mecking, B. A.; Mehrabyan, S.; Melone, J. J.; Mestayer, M. D.; Meyer, C. A.; Mibe, T.; Mikhailov, K.; Minehart, R.; Mirazita, M.; Miskimen, R.; Mokeev, V.; Morand, L.; Morrow, S. A.; Mueller, J.; Mutchler, G. S.; Nadel-Turonski, P.; Napolitano, J.; Nasseripour, R.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Niczyporuk, B. B.; Niyazov, R. A.; Nozar, M.; O'Rielly, G. V.; Osipenko, M.; Ostrovidov, A. I.; Park, K.; Pasyuk, E.; Paterson, C.; Pierce, J.; Pivnyuk, N.; Pocanic, D.; Pogorelko, O.; Pozdniakov, S.; Preedom, B. M.; Price, J. W.; Prok, Y.; Protopopescu, D.; Raue, B. A.; Riccardi, G.; Ricco, G.; Ripani, M.; Ritchie, B. G.; Ronchetti, F.; Rosner, G.; Rossi, P.; Sabatié, F.; Salgado, C.; Santoro, J. P.; Sapunenko, V.; Schumacher, R. A.; Serov, V. S.; Sharabian, Y. G.; Skabelin, A. V.; Smith, E. S.; Smith, L. C.; Sober, D. I.; Stavinsky, A.; Stepanyan, S. S.; Stepanyan, S.; Stokes, B. E.; Stoler, P.; Strauch, S.; Taiuti, M.; Tedeschi, D. J.; Thoma, U.; Tkabladze, A.; Tkachenko, S.; Todor, L.; Tur, C.; Ungaro, M.; Vineyard, M. F.; Vlassov, A. V.; Weinstein, L. B.; Weygand, D. P.; Williams, M.; Wolin, E.; Wood, M. H.; Yegneswaran, A.; Zana, L.; Zhang, J.; Zhao, B.

2006-03-01

We report results from an experiment measuring the semiinclusive reaction H2(e,e'ps) in which the proton ps is moving at a large angle relative to the momentum transfer. If we assume that the proton was a spectator to the reaction taking place on the neutron in deuterium, the initial state of that neutron can be inferred. This method, known as spectator tagging, can be used to study electron scattering from high-momentum (off-shell) neutrons in deuterium. The data were taken with a 5.765 GeV electron beam on a deuterium target in Jefferson Laboratory's Hall B, using the CEBAF large acceptance spectrometer. A reduced cross section was extracted for different values of final state missing mass W*, backward proton momentum p→s, and momentum transfer Q2. The data are compared to a simple plane wave impulse approximation (PWIA) spectator model. A strong enhancement in the data observed at transverse kinematics is not reproduced by the PWIA model. This enhancement can likely be associated with the contribution of final state interactions (FSI) that were not incorporated into the model. Within the framework of the simple spectator model, a “bound neutron structure function” F2neff was extracted as a function of W* and the scaling variable x* at extreme backward kinematics, where the effects of FSI appear to be smaller. For ps>0.4GeV/c, where the neutron is far off-shell, the model overestimates the value of F2neff in the region of x* between 0.25 and 0.6. A dependence of the bound neutron structure function on the neutron's “off-shell-ness” is one possible effect that can cause the observed deviation.

Immunohistochemical screening for viral agents in cheetahs (Acinonyx jubatus) with myelopathy.

PubMed

Shibly, S; Schmidt, P; Robert, N; Walzer, C; Url, A

2006-10-21

Numerous cases of acute-onset progressive ataxia, hindlimb paresis and paralysis of unknown aetiology occurred during 1993 to 2003 in cheetahs (Acinonyx jubatus) within the European Endangered Species Programme (eep). This study describes the immunohistochemical investigation of a possible viral aetiology of the "cheetah myelopathy". Antibodies to feline herpesvirus type 1, canine distemper virus, canine parvovirus and Borna disease virus were applied to formalin-fixed and paraffin-embedded brain and spinal cord sections from 25 affected cheetahs aged between three-and-a-half months and 13 years. Using the avidin-biotin complex technique, none of the antibodies gave positive immunosignals in either the brain or the spinal cord tissue.

Multi-proxy Reconstructions of the Eastern Equatorial Pacific: Measuring Sr/Ca, Ba/Ca, and Li/Mg in Modern Corals Using ICP-OES

NASA Astrophysics Data System (ADS)

Cheung, A. H.; Cole, J. E.; Vetter, L.; Jimenez, G.; Thompson, D. M.; Tudhope, A. W.

2017-12-01

Sea surface temperature (SST) in the Eastern Equatorial Pacific (EEP) exhibits large variability on multiple timescales. These variations are often related to modes of climate variability that exert significant influence on global climate, such as the El Niño Southern Oscillation. However, the short length and sparsity of instrumental data in the EEP limits our ability to discern changes in this region. Geochemical signals in corals can help extend instrumental data further back in time. While δ18O and Sr/Ca are the most commonly analyzed geochemical tracers of SST in corals, they often have site-specific complications. Several alternatives (e.g., Li/Mg) have been proposed to overcome these challenges, but have yet to be applied to long climate records, in part due to the cost and time required to measure these elements. Here, we develop a new method that uses Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES) to analyze Li/Mg, Sr/Ca, and Ba/Ca ratios in coral aragonite. We apply this method to two Porites spp. corals collected from the northern Galapagos archipelago (Wolf and Darwin Islands). We specifically assess the fidelity of Li/Mg and Sr/Ca to reconstruct SST, and Ba/Ca to reconstruct upwelling conditions. Our results confirm that both Li/Mg and Sr/Ca track SST. We show that despite analytical noise, downcore reconstructions of Li/Mg have the potential to provide additional information about SST that is not present in reconstructions generated from Sr/Ca alone. Skeletal Ba/Ca shows little relationship with upwelling, perhaps because of the distance of our sites from the center of upwelling in the southern Galapagos. These results demonstrate the potential for analyzing Sr, Li, Ba, Mg simultaneously in corals with a cost- and time- efficient method, which may be applied to coral paleoclimate sites worldwide.

Acute toxic effects of nerve agent VX on respiratory dynamics and functions following microinsillation inhalation exposure in guinea pigs.

PubMed

Rezk, Peter E; Graham, Jacob R; Moran, Theodore S; Gordon, Richard K; Sciuto, Alfred M; Doctor, Bhupendra P; Nambiar, Madhusoodana P

2007-03-01

Exposure to a chemical warfare nerve agent (CWNA) leads to severe respiratory distress, respiratory failure, or death if not treated. We investigated the toxic effects of nerve agent VX on the respiratory dynamics of guinea pigs following exposure to 90.4 mug/m3 of VX or saline by microinstillation inhalation technology for 10 min. Respiratory parameters were monitored by whole-body barometric plethysmography at 4, 24, and 48 h, 7 d, 18 d, and 4 wk after VX exposure. VX-exposed animals showed a significant decrease in the respiratory frequency (RF) at 24 and 48 h of recovery (p value .0329 and .0142, respectively) compared to the saline control. The tidal volume (TV) slightly increased in VX exposed animals at 24 and significantly at 48 h (p = .02) postexposure. Minute ventilation (MV) increased slightly at 4 h but was reduced at 24 h and remained unchanged at 48 h. Animals exposed to VX also showed an increase in expiratory (Te) and relaxation time (RT) at 24 and 48 h and a small reduction in inspiratory time (Ti) at 24 h. A significant increase in end expiratory pause (EEP) was observed at 48 h after VX exposure (p = .049). The pseudo lung resistance (Penh) was significantly increased at 4 h after VX exposure and remained slightly high even at 48 h. Time-course studies reveal that most of the altered respiratory dynamics returned to normal at 7 d after VX exposure except for EEP, which was high at 7 d and returned to normal at 18 d postexposure. After 1 mo, all the monitored respiratory parameters were within normal ranges. Bronchoalveolar lavage (BAL) 1 mo after exposure showed virtually no difference in protein levels, cholinesterase levels, cell number, and cell death in the exposed and control animals. These results indicate that sublethal concentrations of VX induce changes in respiratory dynamics and functions that over time return to normal levels.

Holocene Deep Ocean Variability Detected with Individual Benthic Foraminifera

NASA Astrophysics Data System (ADS)

Bova, S. C.; Herbert, T.; Fox-Kemper, B.

2015-12-01

Historical observations of deep ocean temperatures (>700 m water depth) show apparently unprecedented rates of warming over the past half century that parallel observed surface warming, on the order of 0.1°C/decade (Purkey and Johnson 2010). Most water masses below 700 m depth, however, have not been at the sea surface where they exchange heat and carbon with the atmosphere since well before industrialization (Gebbie and Huybers 2012). How then has the heat content of isolated deep water masses responded to climate change over the last century? In models, wave mechanisms propagate thermocline anomalies quickly (Masuda et al. 2010), but these dynamics are not fully understood. We therefore turn to the sedimentary record to constrain the bounds of earlier variability from Holocene anomalies. The oxygen isotopic composition (δ18O) of individual benthic foraminifera provide approximately month-long snapshots of the temperature and salinity of ambient deep water during calcification. We exploit the short lifespan of these organisms to reconstruct variability in δ18Oshell, and thus the variability in deep water temperature and salinity, during five 200-yr Holocene intervals at 1000 m water depth in the Eastern Equatorial Pacific (EEP). Modern variability in benthic foraminifer δ18O was too weak to detect but variability at 1000 m water depth in the EEP exceeded our detection limit during two Holocene intervals at high confidence (p<0.01), with δ18O anomalies up to ~0.6 ± 0.15‰ that persist for a month or longer. Although the source of these anomalies remains speculative, rapid communication between the surface and deep ocean that operates on human timescales, faster than previously recognized, or intrinsic variability that has not been active during the history of ocean observations are potential explanations. Further work combining models and high-resolution proxy data is needed to identify the mechanism and global extent of this type of subsurface variability in the global oceans.

Does Flexible Arterial Tubing Retain More Hemodynamic Energy During Pediatric Pulsatile Extracorporeal Life Support?

PubMed

Wang, Shigang; Kunselman, Allen R; Ündar, Akif

2017-01-01

The objective of this study was to evaluate the hemodynamic performance and energy transmission of flexible arterial tubing as the arterial line in a simulated pediatric pulsatile extracorporeal life support (ECLS) system. The ECLS circuit consisted of a Medos Deltastream DP3 diagonal pump head, Medos Hilite 2400 LT oxygenator, Biomedicus arterial/venous cannula (10 Fr/14 Fr), 3 feet of polyvinyl chloride (PVC) arterial tubing or latex rubber arterial tubing, primed with lactated Ringer's solution and packed red blood cells (hematocrit 40%). Trials were conducted at flow rates of 300 to 1200 mL/min (300 mL/min increments) under nonpulsatile and pulsatile modes at 36°C using either PVC arterial tubing (PVC group) or latex rubber tubing (Latex group). Real-time pressure and flow data were recorded using a custom-based data acquisition system. Mean pressures and energy equivalent pressures (EEP) were the same under nonpulsatile mode between the two groups. Under pulsatile mode, EEPs were significantly great than mean pressure, especially in the Latex group (P < 0.05). There was no difference between the two groups with regards to pressure drops across ECLS circuit, but pulsatile flow created more pressure drops than nonpulsatile flow (P < 0.05). Surplus hemodynamic energy (SHE) levels were always higher in the Latex group than in the PVC group at all sites. Although total hemodynamic energy (THE) losses were higher under pulsatile mode compared to nonpulsatile mode, more THE was delivered to the pseudopatient, particularly in the Latex group (P < 0.05). The results showed that the flexible arterial tubing retained more hemodynamic energy passing through it under pulsatile mode while mean pressures and pressure drops across the ECLS circuit were similar between PVC and latex rubber arterial tubing. Further studies are warranted to verify our findings. © 2016 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

HadCM3 Simulations of ENSO behaviour during the Mid-Pliocene Warm Period

NASA Astrophysics Data System (ADS)

Bonham, S. G.; Haywood, A. M.; Lunt, D. J.

2009-04-01

It has been suggested that a permanent El Niño state existed during the mid-Pliocene (ca. 3.3 - 3.0 Ma BP), with a west-to-east temperature gradient in the tropical Pacific considerably weaker than today. This is based upon a number of palaeoceanographic studies which have examined the development of the thermocline and SST gradient in the tropical Pacific over the last five million years. This state is now being referred to as El Padre in recognition of the fact that a mean state warming in EEP SSTs does not necessarily imply the presence of a permanent El Niño. Recent results from mid-Pliocene coupled ocean-atmosphere model simulations have shown clear ENSO variability whilst maintaining the warming in the EEP. This research expands on this study, using the UK Met Office GCM (HadCM3), to examine the behaviour and characteristics of ENSO in two mid-Pliocene simulations (with an open and closed Central American Seaway, CAS) compared with a control pre-industrial run, as well as produce a detailed profile of the mean state climates. The results shown include timescales of ENSO variability across four regions in the Pacific, as well as frequency, EOF and wavelet analysis. We have also looked at the interaction of ENSO with the annual cycle and the onset of ENSO events, and the interdecadal variability in the simulations. The initial timeseries produced have shown a greater variability of ENSO during the closed CAS mid-Pliocene simulation where the system oscillates between events much more frequently than seen in the pre-industrial run. The EOF and wavelet analyses quantify this behaviour, showing that the variability is approximately 15% higher over the central and eastern equatorial Pacific, with a period of oscillation of 2-5 years compared with 4-8 years for the pre-industrial simulation. These results will be compared with those obtained from the second mid-Pliocene simulation (open CAS).

Way Beyond Widgets: Delivering Integrated Lighting Design in Actionable Solutions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Myer, Michael; Richman, Eric E.; Jones, Carol C.

2008-08-17

Previously, energy-efficiency strategies for commercial spaces have focused on using efficient equipment without providing specific detailed instructions. Designs by experts in their fields are an energy-efficiency product in its own right. A new national program has developed interactive application-specific lighting designs for widespread use in four major commercial sectors. This paper will describe the technical basis for the solutions, energy efficiency and cost-savings methodology, and installations and measurement/verification to-date. Lighting designs have been developed for five types of retail stores (big box, small box, grocery, specialty market, and pharmacy) and are planned for the office, healthcare, and education sectors asmore » well. Nationally known sustainable lighting designers developed the designs using high-performance commercially available products, daylighting, and lighting controls. Input and peer review was received by stakeholders, including manufacturers, architects, utilities, energy-efficiency program sponsors (EEPS), and end-users (i.e., retailers). An interactive web tool delivers the lighting solutions and analyzes anticipated energy savings using project-specific inputs. The lighting solutions were analyzed against a reference building using the space-by-space method as allowed in the Energy Standard for Buildings Except Low-Rise Residential Buildings (ASHRAE 2004) co-sponsored by the American Society of Heating, Refrigeration, and Air Conditioning Engineers (ASHRAE) and the Illuminating Engineering Society of North America (IESNA). The results showed that the design vignettes ranged from a 9% to 28% reduction in the allowed lighting power density. Detailed control strategies are offered to further reduce the actual kilowatt-hour power consumption. When used together, the lighting design vignettes and control strategies show a modeled decrease in energy consumption (kWh) by 33% to 50% below the baseline design.« less

Ada Compiler Validation Summary Report: Certificate Number: 891126I1. 10221 Telesoft TeleGen2 Ada Development System for HP 9000/340 x MVME133a-20.

DTIC Science & Technology

1989-11-26

e(rrors.only x - F(ie..only -.errs x -f(ormat x -G(raph x x -g(eierate..ofr x -l(nline x -i(nhibit x -k(eep x x -L( ist x -M(ap x -m(airi x -N(ame x...erbose -e(rrors-.only C -CmIe to object -c/pu.type 20 -d(ebug -kieep -O(ptiznize <key+,> - S(ource..asm -u(pdate-lib <key.-> -x(ecution-.profile -L( ist ...generate execution-profile code. 2.1.12 Listing options: -C(ontext <value> Include 1 line of context with error 2.1.13.1 message. -L( ist Do not

Conducting polymer electrodes for visual prostheses.

PubMed

Green, R A; Devillaine, F; Dodds, C; Matteucci, P; Chen, S; Byrnes-Preston, P; Poole-Warren, L A; Lovell, N H; Suaning, G J

2010-01-01

Conducting polymers (CPs) have the potential to provide superior neural interfaces to conventional metal electrodes by introducing more efficient charge transfer across the same geometric area. In this study the conducting polymer poly(ethylene dioxythiophene) (PEDOT) was coated on platinum (Pt) microelectrode arrays. The in vitro electrical characteristics were assessed during biphasic stimulation regimes applied between electrode pairs. It was demonstrated that PEDOT could reduce the potential excursion at a Pt electrode interface by an order of magnitude. The charge injection limit of PEDOT was found to be 15 x larger than Pt. Additionally, PEDOT coated electrodes were acutely implanted in the suprachoroidal space of a cat retina. It was demonstrated that PEDOT coated electrodes also had lower potential excursions in vivo and electrically evoked potentials (EEPs) could be detected within the vision cortex.

Exclusive quasi-free proton knockout from oxygen isotopes at intermediate energies

NASA Astrophysics Data System (ADS)

Kawase, Shoichiro; Uesaka, Tomohiro; Tang, Tsz Leung; Beaumel, Didier; Dozono, Masanori; Fukunaga, Taku; Fujii, Toshihiko; Fukuda, Naoki; Galindo-Uribarri, Alfredo; Hwang, Sanghoon; Inabe, Naoto; Kawabata, Takahiro; Kawahara, Tomomi; Kim, Wooyoung; Kisamori, Keiichi; Kobayashi, Motoki; Kubo, Toshiyuki; Kubota, Yuki; Kusaka, Kensuke; Lee, Cheongsoo; Maeda, Yukie; Matsubara, Hiroaki; Michimasa, Shin'ichiro; Miya, Hiroyuki; Noro, Tetsuo; Nozawa, Yuki; Obertelli, Alexandre; Ogata, Kazuyuki; Ota, Shinsuke; Padilla-Rodal, Elizabeth; Sakaguchi, Satoshi; Sakai, Hideyuki; Sasano, Masaki; Shimoura, Susumu; Stepanyan, Samvel; Suzuki, Hiroshi; Suzuki, Tomokazu; Takaki, Motonobu; Takeda, Hiroyuki; Tamii, Atsushi; Tokieda, Hiroshi; Wakasa, Tomotsugu; Wakui, Takashi; Yako, Kentaro; Yasuda, Jumpei; Yanagisawa, Yoshiyuki; Yokoyama, Rin; Yoshida, Kazuki; Yoshida, Koichi; Zenihiro, Juzo

2018-02-01

The dependence of the single-particle strength on the difference between proton and neutron separation energies is studied for oxygen isotopes in a wide range of isospins. The cross sections of the quasi-free (p,2p) reaction on ^{14,16,18,22,24}O were measured at intermediate energies. The measured cross sections are compared to predictions based on the distorted wave impulse approximation and shell-model psd valence-space spectroscopic factors. The reduction factors, which are the ratio of the experimental cross sections to the theoretical predictions, show no apparent dependence on the proton-neutron separation energy difference. The result is compatible with the result of the (e,e^'p) reaction on stable targets and with the predictions of recent ab initio calculations.

A scaling approach to Budyko's framework and the complementary relationship of evapotranspiration in humid environments: case study of the Amazon River basin

NASA Astrophysics Data System (ADS)

Carmona, A. M.; Poveda, G.; Sivapalan, M.; Vallejo-Bernal, S. M.; Bustamante, E.

2015-10-01

This paper studies a 3-D generalization of Budyko's framework designed to capture the mutual interdependence among long-term mean actual evapotranspiration (E), potential evapotranspiration (Ep) and precipitation (P). For this purpose we use three dimensionless and dependent quantities: Ψ = E/P, Φ = Ep/P and Ω = E/Ep. This 3-D space and its 2-D projections provide an interesting setting to test the physical soundness of Budyko's hypothesis. We demonstrate analytically that Budyko-type equations are unable to capture the physical limit of the relation between Ω and Φ in humid environments, owing to the unfeasibility of Ep/P → 0 at E/Ep = 1. Using data from 146 sub-catchments in the Amazon River basin we overcome this inconsistency by proposing a physically consistent power law: Ψ = k Φe, with k = 0.66, and e = 0.83 (R2 = 0.93). This power law is compared with two other Budyko-type equations. Taking into account the goodness of fits and the ability to comply with the physical limits of the 3-D space, our results show that the power law is better suited to model the coupled water and energy balances within the Amazon River basin. Moreover, k is found to be related to the partitioning of energy via evapotranspiration in terms of Ω. This suggests that our power law implicitly incorporates the complementary relationship of evapotranspiration into the Budyko curve, which is a consequence of the dependent nature of the studied variables within our 3-D space. This scaling approach is also consistent with the asymmetrical nature of the complementary relationship of evapotranspiration. Looking for a physical explanation for the parameters k and e, the inter-annual variability of individual catchments is studied. Evidence of space-time symmetry in Amazonia emerges, since both between-catchment and between-year variability follow the same Budyko curves. Finally, signs of co-evolution of catchments are explored by linking spatial patterns of the power law parameters with fundamental characteristics of the Amazon River basin. In general, k and e are found to be related to vegetation, topography and water in soils.

Evidence for changes in subsurface circulation in the late Eocene equatorial Pacific from radiolarian-bound nitrogen isotope values

NASA Astrophysics Data System (ADS)

Robinson, Rebecca S.; Moore, Theodore C.; Erhardt, Andrea M.; Scher, Howie D.

2015-07-01

Microfossil-bound organic matter represents an important archive of surface ocean environmental information. Sedimentary nitrogen (N) isotope reconstructions of surface nitrate consumption and nitrogen source changes are made using fossil diatom (autotrophs) and planktic foraminiferal (heterotrophs)-bound organic matter with success. However, because diatoms and planktic foraminifera are poorly preserved and sedimentary organic matter content is near zero during the late Eocene, our ability to examine nutrient dynamics across this important climate transition is limited. Here we present new data exploring the use of N isotope records from radiolarian tests. A comparison of surface ocean nitrate and core top bulk and radiolarian N isotope values (as δ15N) from the equatorial Pacific indicates that radiolarian-N records δ15N variability with fidelity but that a significant offset exists between bulk sedimentary and diatom δ15N values and those measured from radiolarians (~7.1 ± 1.1‰). A downcore profile of radiolarian δ15N values is compared to siliceous microfossil assemblage changes across the Eocene-Oligocene boundary. Average of radiolarian-bound δ15N values is 0.5 ± 2.0‰, which, when corrected using the offset derived from the modern surface samples, suggests that the mean nitrogen isotopic composition of the early Cenozoic eastern Pacific was not significantly different from today. The overall trend, of decreasing δ15N values with decreasing export productivity, is consistent with either a regional decline in pelagic denitrification or a large-scale change in nutrient sources to the eastern equatorial Pacific (EEP), both linked to the cooling climate and changing intermediate water circulation. Decreasing/low δ15N values cooccur with high radiolarian species turnover at ~35.5 and 34 Ma, suggestive of a significant ecological change in the EEP, consistent with cooling and water mass distribution changes. The preliminary results suggest that radiolarian-bound organic nitrogen represents another promising archive and underscores the fact that the different microfossil fractions must be separated to ensure robust results.

Assessment by cytogenetic analysis of the radioprotection properties of propolis extract.

PubMed

Montoro, A; Almonacid, M; Serrano, J; Saiz, M; Barquinero, J F; Barrios, L; Verdú, G; Pérez, J; Villaescusa, J I

2005-01-01

Propolis obtained from honeybee hives has been used in folk medicine as an anti-inflammatory, anti-carcinogenic or immunomodulatory agent. In animal studies, the radioprotector effect of propolis has been attributed to its free-radical scavenging properties. The present study was carried out to show the protective properties of propolis extract against DNA damage induced by gamma irradiation. The evaluation of the radioprotective effect of propolis has been carried out by the analysis of chromosome aberration induction after several doses of gamma rays. The results of an analysis in the presence of ethanol extract of propolis (EEP) were compared with the dose-effect calibration curve for gamma-rays by analysis of chromosome aberrations without propolis, a decrease in the radiation-induced chromosome aberrations has been observed to be higher than 50% for all the doses.

Acoustic-wave sensor for ambient monitoring of a photoresist-stripping agent

DOEpatents

Pfeifer, K.B.; Hoyt, A.E.; Frye, G.C.

1998-08-18

The acoustic-wave sensor is disclosed. The acoustic-wave sensor is designed for ambient or vapor-phase monitoring of a photoresist-stripping agent such as N-methylpyrrolidinone (NMP), ethoxyethylpropionate (EEP) or the like. The acoustic-wave sensor comprises an acoustic-wave device such as a surface-acoustic-wave (SAW) device, a flexural-plate-wave (FPW) device, an acoustic-plate-mode (APM) device, or a thickness-shear-mode (TSM) device (also termed a quartz crystal microbalance or QCM) having a sensing region on a surface thereof. The sensing region includes a sensing film for sorbing a quantity of the photoresist-stripping agent, thereby altering or shifting a frequency of oscillation of an acoustic wave propagating through the sensing region for indicating an ambient concentration of the agent. According to preferred embodiments of the invention, the acoustic-wave device is a SAW device; and the sensing film comprises poly(vinylacetate), poly(N-vinylpyrrolidinone), or poly(vinylphenol). 3 figs.

Acoustic-wave sensor for ambient monitoring of a photoresist-stripping agent

DOEpatents

Pfeifer, Kent B.; Hoyt, Andrea E.; Frye, Gregory C.

1998-01-01

The acoustic-wave sensor. The acoustic-wave sensor is designed for ambient or vapor-phase monitoring of a photoresist-stripping agent such as N-methylpyrrolidinone (NMP), ethoxyethylpropionate (EEP) or the like. The acoustic-wave sensor comprises an acoustic-wave device such as a surface-acoustic-wave (SAW) device, a flexural-plate-wave (FPW) device, an acoustic-plate-mode (APM) device, or a thickness-shear-mode (TSM) device (also termed a quartz crystal microbalance or QCM) having a sensing region on a surface thereof. The sensing region includes a sensing film for sorbing a quantity of the photoresist-stripping agent, thereby altering or shifting a frequency of oscillation of an acoustic wave propagating through the sensing region for indicating an ambient concentration of the agent. According to preferred embodiments of the invention, the acoustic-wave device is a SAW device; and the sensing film comprises poly(vinylacetate), poly(N-vinylpyrrolidinone), or poly(vinylphenol).

[Particulate distribution characteristics of Chinese phrase V diesel engine based on butanol-diesel blends].

PubMed

Lou, Di-Ming; Xu, Ning; Fan, Wen-Jia; Zhang, Tao

2014-02-01

With a common rail diesel engine without any modification and the engine exhaust particle number and particle size analyzer EEPS, this study used the air-fuel ratio to investigate the particulate number concentration, mass concentration and number distribution characteristics of a diesel engine fueled with butanol-diesel blends (Bu10, Bu15, Bu20, Bu30 and Bu40) and petroleum diesel. The results show: for all test fuels, the particle number distributions turn to be unimodal. With the increasing of butanol, numbers of nucleation mode particles and small accumulation mode particle decrease. At low speed and low load conditions, the number of large accumulation mode particle increases slightly, but under higher speed and load conditions, the number does not increase. When the fuels contain butanol, the total particle number concentration and mass concentration in all conditions decrease and that is more obvious at high speed load.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schellenberg, Matthew J; Appel, C Denise; Adhikari, Sanjay

The topoisomerase II (topo II) DNA incision-and-ligation cycle can be poisoned (for example following treatment with cancer chemotherapeutics) to generate cytotoxic DNA double-strand breaks (DSBs) with topo II covalently conjugated to DNA. Tyrosyl-DNA phosphodiesterase 2 (Tdp2) protects genomic integrity by reversing 5'-phosphotyrosyl–linked topo II–DNA adducts. Here, X-ray structures of mouse Tdp2–DNA complexes reveal that Tdp2 β–2-helix–β DNA damage–binding 'grasp', helical 'cap' and DNA lesion–binding elements fuse to form an elongated protein-DNA conjugate substrate-interaction groove. The Tdp2 DNA-binding surface is highly tailored for engagement of 5'-adducted single-stranded DNA ends and restricts nonspecific endonucleolytic or exonucleolytic processing. Structural, mutational and functional analysesmore » support a single–metal ion catalytic mechanism for the exonuclease-endonuclease-phosphatase (EEP) nuclease superfamily and establish a molecular framework for targeted small-molecule blockade of Tdp2-mediated resistance to anticancer topoisomerase drugs.« less

7 CFR 1467.9 - Wetlands Reserve Enhancement Program.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Wetlands Reserve Enhancement Program. 1467.9 Section... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS WETLANDS RESERVE PROGRAM § 1467.9 Wetlands Reserve Enhancement Program. (a) Wetlands Reserve Enhancement Program (WREP). (1) The...

Peripheral ARtery Atherosclerotic DIsease and SlEep disordered breathing (PARADISE) trial - protocol for an observational cohort study.

PubMed

Szymański, Filip M; Gałązka, Zbigniew; Płatek, Anna E; Górko, Dariusz; Ostrowski, Tomasz; Adamkiewicz, Karolina; Łęgosz, Paweł; Ryś, Anna; Semczuk-Kaczmarek, Karolina; Celejewski, Krzysztof; Filipiak, Krzysztof J

2017-01-01

Peripheral arterial disease (PAD) is in fact a group of disease entities with different symptoms and course but a common underlying cause, i.e. atherosclerosis. Atherosclerosis is known to be aggravated by several cardiovascular risk factors, including obstructive sleep apnoea (OSA). Following paper is a protocol for the Peripheral ARtery Atherosclerotic DIsease and SlEep disordered breathing (PARADISE) trial, which aims to describe the prevalence of OSA in PAD patients scheduled for revascularisation, and to determine the effect of OSA on the procedure outcomes. The PARADISE study is an observational cohort trial. It plans to include 200 consecutive patients hospitalised for revascularisation due to PAD. In every patient an overnight sleep study will be performed to diagnose sleep disorders. Accord¬ing to the results of the test, patients will be divided into two groups: group A - patients with OSA, and group B - patients without OSA (control group). All patients will also be screened for classical and non-classical cardiovascular risk factors. In some of the patients, during surgery, a fragment of atherosclerotic plaque will be collected for further testing. Patients will be followed for one year for adverse events and end-points. Primary end-point of the study will be the failure of revascularisa¬tion defined as recurrence or new onset of the symptoms of ischaemia from the treated region, a need for re-operation or procedure revision, or recurrence of ischaemia signs on the imaging tests. The data obtained will help determine the incidence of OSA in the population of patients with PAD. The au¬thors expect to show that, as with other cardiovascular diseases associated with atherosclerosis, also in patients with PAD the incidence of undiagnosed OSA is high and its presence is associated with elevated cholesterol, inflammatory markers, and higher prevalence of arterial hypertension and poor control of other cardiovascular risk factors. In addition, due to increased oxidative stress and vascular endothelial injury associated with OSA, patients afflicted with this condition will not only have more advanced atherosclerotic lesions, but also in their histopathological examination their atherosclerotic plaque will exhibit evidence of greater instability and adverse morphology. We also expect to show that in patients with OSA, achieving cor¬rect control of cardiovascular risk factors will be more difficult. The study may improve PAD control through assuring better multispecialty care in PAD patients.

Millennial Variability of Eastern Equatorial Bottom Water Oxygenation and Atmospheric CO2 over the past 100 kyr

NASA Astrophysics Data System (ADS)

Marcantonio, F.; Loveley, M.; Wisler, M.; Hostak, R.; Hertzberg, J. E.; Schmidt, M. W.; Lyle, M. W.

2017-12-01

Storage of respired carbon in the deep ocean may play a significant role in lowering atmospheric CO2 concentrations by about 80 ppm during the last glacial maximum compared to pre-industrial times. The cause of this sequestration and the subsequent release of the deep respired carbon pool at the last termination remains elusive. Within the last glacial period, on millennial timescales, the relationship between the CO2 cycle and any waxing and waning of a deep respired pool also remains unclear. To further our understanding of the millennial variability in the storage of a deep-ocean respired carbon pool during the last glacial, we measure authigenic uranium and 230Th-derived non-lithogenic barium fluxes (xsBa flux) in two high-sedimentation-rate cores from the Panama Basin of the Eastern Equatorial Pacific (EEP) (8JC, 6° 14.0' N, 86° 02.6' W; 1993 m water depth; 17JC 00° 10.8' S, 85° 52.0' W; 2846 m water depth). Sediment authigenic U concentrations are controlled by the redox state of sediments which, in turn, is a function of the rain of organic material from the surface ocean and the oxygen content of bottom waters. At both 8JC and 17JC, the mismatch between xsBa fluxes, a proxy for the reconstruction of oceanic productivity, and authigenic uranium concentrations suggests that the primary control of the latter values is changes in bottom water oxygenation. Peak authigenic uranium concentrations occur during glacial periods MIS 2, 3, and 4, respectively, and are two to three times higher than those during interglacial periods, MIS 1 and 5. EEP bottom waters were likely suboxic during times of the last glacial period when atmospheric CO2 concentrations were at their lowest concentrations. In addition, the pattern of increased deep-water oxygenation during times of higher CO2 during the last glacial is similar to that reported in a study of authigenic U in sediments from the Antarctic Zone of the Southern Ocean (Jaccard et al., 2016). We suggest that a respired carbon pool existed within a large swath of the abyssal Southern and Pacific Oceans throughout the entire last glacial cycle, and that this respired carbon was periodically released through increased ventilation of deep ocean waters. Jaccard et al. (2016) Nature 530, 207-210.

Variability of neodymium isotopes associated with planktonic foraminifera in the Pacific Ocean during the Holocene and Last Glacial Maximum

NASA Astrophysics Data System (ADS)

Hu, Rong; Piotrowski, Alexander M.; Bostock, Helen C.; Crowhurst, Simon; Rennie, Victoria

2016-08-01

The deep Pacific Ocean holds the largest oceanic reservoir of carbon which may interchange with the atmosphere on climatologically important timescales. The circulation of the deep Pacific during the Last Glacial Maximum (LGM), however, is not well understood. Neodymium (Nd) isotopes of ferromanganese oxide coatings precipitated on planktonic foraminifera are a valuable proxy for deep ocean water mass reconstruction in paleoceanography. In this study, we present Nd isotope compositions (εNd) of planktonic foraminifera for the Holocene and the LGM obtained from 55 new sites widely distributed in the Pacific Ocean. The Holocene planktonic foraminiferal εNd results agree with the proximal seawater data, indicating that they provide a reliable record of modern bottom water Nd isotopes in the deep Pacific. There is a good correlation between foraminiferal εNd and seawater phosphate concentrations (R2 = 0.80), but poorer correlation with silicate (R2 = 0.37). Our interpretation is that the radiogenic Nd isotope is added to the deep open Pacific through particle release from the upper ocean during deep water mass advection and aging. The data thus also imply the Nd isotopes in the Pacific are not likely to be controlled by silicate cycling. In the North Pacific, the glacial Nd isotopic compositions are similar to the Holocene values, indicating that the Nd isotope composition of North Pacific Deep Water (NPDW) remained constant (-3.5 to -4). During the LGM, the southwest Pacific cores throughout the water column show higher εNd corroborating previous studies which suggested a reduced inflow of North Atlantic Deep Water to the Pacific. However, the western equatorial Pacific deep water does not record a corresponding radiogenic excursion, implying reduced radiogenic boundary inputs during the LGM probably due to a shorter duration of seawater-particle interaction in a stronger glacial deep boundary current. A significant negative glacial εNd excursion is evident in mid-depth (1-2 km) cores of the eastern equatorial Pacific (EEP) which may suggest a stronger influence of NPDW return flow to the core sites and decreased local input in the EEP. Taken together, our Nd records do not support a dynamically slower glacial Pacific overturning circulation, and imply that the increased carbon inventory of Pacific deep water might be due to poor high latitude air-sea exchange and increased biological pump efficiency in glacial times.

34 CFR 225.3 - What regulations apply to the Credit Enhancement for Charter School Facilities Program?

Code of Federal Regulations, 2013 CFR

2013-07-01

... Charter School Facilities Program? 225.3 Section 225.3 Education Regulations of the Offices of the... ENHANCEMENT FOR CHARTER SCHOOL FACILITIES PROGRAM General § 225.3 What regulations apply to the Credit Enhancement for Charter School Facilities Program? The following regulations apply to the Credit Enhancement...

34 CFR 225.3 - What regulations apply to the Credit Enhancement for Charter School Facilities Program?

Code of Federal Regulations, 2014 CFR

2014-07-01

... Charter School Facilities Program? 225.3 Section 225.3 Education Regulations of the Offices of the... ENHANCEMENT FOR CHARTER SCHOOL FACILITIES PROGRAM General § 225.3 What regulations apply to the Credit Enhancement for Charter School Facilities Program? The following regulations apply to the Credit Enhancement...

34 CFR 225.3 - What regulations apply to the Credit Enhancement for Charter School Facilities Program?

Code of Federal Regulations, 2012 CFR

2012-07-01

... Charter School Facilities Program? 225.3 Section 225.3 Education Regulations of the Offices of the... ENHANCEMENT FOR CHARTER SCHOOL FACILITIES PROGRAM General § 225.3 What regulations apply to the Credit Enhancement for Charter School Facilities Program? The following regulations apply to the Credit Enhancement...

34 CFR 225.3 - What regulations apply to the Credit Enhancement for Charter School Facilities Program?

Code of Federal Regulations, 2011 CFR

2011-07-01

... Charter School Facilities Program? 225.3 Section 225.3 Education Regulations of the Offices of the... ENHANCEMENT FOR CHARTER SCHOOL FACILITIES PROGRAM General § 225.3 What regulations apply to the Credit Enhancement for Charter School Facilities Program? The following regulations apply to the Credit Enhancement...

34 CFR 225.3 - What regulations apply to the Credit Enhancement for Charter School Facilities Program?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Charter School Facilities Program? 225.3 Section 225.3 Education Regulations of the Offices of the... ENHANCEMENT FOR CHARTER SCHOOL FACILITIES PROGRAM General § 225.3 What regulations apply to the Credit Enhancement for Charter School Facilities Program? The following regulations apply to the Credit Enhancement...

75 FR 16719 - Agricultural Water Enhancement Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-02

... DEPARTMENT OF AGRICULTURE Commodity Credit Corporation Agricultural Water Enhancement Program... Energy Act of 2008 (2008 Act) established the Agricultural Water Enhancement Program (AWEP) by amending... to implement agricultural water enhancement activities on agricultural land for the purposes of...

75 FR 18146 - Wetlands Reserve Enhancement Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-09

... DEPARTMENT OF AGRICULTURE Commodity Credit Corporation Wetlands Reserve Enhancement Program AGENCY... assistance will be made available in fiscal year (FY) 2010 for the Wetlands Reserve Enhancement Program (WREP... partners to help enhance conservation outcomes on wetlands and adjacent lands. WREP targets and leverages...

Recent results and perspectives on cosmology and fundamental physics from microwave surveys

NASA Astrophysics Data System (ADS)

Burigana, Carlo; Battistelli, Elia Stefano; Benetti, Micol; Cabass, Giovanni; de Bernardis, Paolo; di Serego Alighieri, Sperello; di Valentino, Eleonora; Gerbino, Martina; Giusarma, Elena; Gruppuso, Alessandro; Liguori, Michele; Masi, Silvia; Norgaard-Nielsen, Hans Ulrik; Rosati, Piero; Salvati, Laura; Trombetti, Tiziana; Vielva, Patricio

2016-04-01

Recent cosmic microwave background (CMB) data in temperature and polarization have reached high precision in estimating all the parameters that describe the current so-called standard cosmological model. Recent results about the integrated Sachs-Wolfe (ISW) effect from CMB anisotropies, galaxy surveys, and their cross-correlations are presented. Looking at fine signatures in the CMB, such as the lack of power at low multipoles, the primordial power spectrum (PPS) and the bounds on non-Gaussianities, complemented by galaxy surveys, we discuss inflationary physics and the generation of primordial perturbations in the early universe. Three important topics in particle physics, the bounds on neutrinos masses and parameters, on thermal axion mass and on the neutron lifetime derived from cosmological data are reviewed, with attention to the comparison with laboratory experiment results. Recent results from cosmic polarization rotation (CPR) analyses aimed at testing the Einstein equivalence principle (EEP) are presented. Finally, we discuss the perspectives of next radio facilities for the improvement of the analysis of future CMB spectral distortion experiments.

Model development and parameter estimation for a hybrid submerged membrane bioreactor treating Ametryn.

PubMed

Navaratna, Dimuth; Shu, Li; Baskaran, Kanagaratnam; Jegatheesan, Veeriah

2012-06-01

A lab-scale membrane bioreactor (MBR) was used to remove Ametryn from synthetic wastewater. It was found that concentrations of MLSS and extra-cellular polymeric substances (EPS) in MBR mixed liquor fluctuated (production and decay) differently for about 40 days (transition period) after the introduction of Ametryn. During the subsequent operations with higher organic loading rates, it was also found that a low net biomass yield (higher death rate) and a higher rate of fouling of membrane (a very high rate during the first 48 h) due to increased levels of bound EPS (eEPS) in MBR mixed liquor. A mathematical model was developed to estimate the kinetic parameters before and after the introduction of Ametryn. This model will be useful in simulating the performance of a MBR treating Ametryn in terms of flux, rate of fouling (in terms of transmembrane pressure and membrane resistance) as well as treatment efficiency. Copyright © 2011 Elsevier Ltd. All rights reserved.

Enhancing programming logic thinking using analogy mapping

NASA Astrophysics Data System (ADS)

Sukamto, R. A.; Megasari, R.

2018-05-01

Programming logic thinking is the most important competence for computer science students. However, programming is one of the difficult subject in computer science program. This paper reports our work about enhancing students' programming logic thinking using Analogy Mapping for basic programming subject. Analogy Mapping is a computer application which converts source code into analogies images. This research used time series evaluation and the result showed that Analogy Mapping can enhance students' programming logic thinking.

78 FR 60169 - Federal Acquisition Regulation; Pilot Program for Enhancement of Contractor Employee...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-30

... 9000-AM56 Federal Acquisition Regulation; Pilot Program for Enhancement of Contractor Employee... program enhancing whistleblower protections for contractor employees. DATES: Effective: September 30, 2013... contractor employees at FAR subpart 3.9. The pilot program is mandated by section 828, entitled ``Pilot...

Enhancing the educational achievement of at-risk youth.

PubMed

Schinke, S P; Cole, K C; Poulin, S R

2000-03-01

This study examined a non-school program aimed at enhancing the educational performance of economically disadvantaged early adolescents who live in public housing. The educational enhancement program included discussions with adults, writing activities, leisure reading, homework, helping others, and games using cognitive skills. A three-arm research design juxtaposed program youth who received educational enhancements with comparison youth in affiliated facilities who did not receive the program and with control youth in other community programs without educational enhancements. From youths, follow-up data collected 2 1/2 years after baseline revealed uniformly positive outcomes for program youth on measures of reading, verbal skills, writing, and tutoring. Teacher reports at final follow-up favored program and comparison youth over controls on measures of reading, writing, games, overall school performance, and interest in class material. School grades were higher for program youth than for comparison and control youth for reading, spelling, history, science, and social studies. Overall grade averages were higher for program youth versus comparisons and controls, as was school attendance. Study data lend empirical support to the provision of educational enhancements in non-school settings for at-risk youths.

The Enhancement Seminar Model as a Strategy to Promote Diversity and Student Success in MSW Programs

ERIC Educational Resources Information Center

Watson, Larry D.; Rycraft, Joan R.

2010-01-01

This study evaluates the effectiveness of an enhancement program by examining a cohort of 57 students admitted on probationary status to an MSW program in 2002 and required to participate in the enhancement program. The demographics for students admitted on probation demonstrate that the program is effective in increasing the diversity of the…

75 FR 73027 - Cooperative Conservation Partnership Initiative and Wetlands Reserve Enhancement Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-29

... Corporation Cooperative Conservation Partnership Initiative and Wetlands Reserve Enhancement Program AGENCY... Initiative. SUMMARY: The Natural Resources Conservation Service (NRCS) announces the availability of... Partnership Initiative (CCPI) and up to $25 million in the Wetlands Reserve Enhancement Program (WREP) through...

76 FR 17842 - Credit Enhancement for Charter School Facilities Program

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-31

... DEPARTMENT OF EDUCATION Credit Enhancement for Charter School Facilities Program AGENCY: Office of... for Charter School Facilities program (March 11 NIA). This notice makes two corrections to the March...-mail: [email protected] ; or by mail: (Attention: Credit Enhancement for Charter School Facilities...

A structural equation model on the attributes of a skills enhancement program affecting clinical competence of pre-graduate nursing students.

PubMed

Rebueno, Ma Carina D R; Tiongco, Dyan Dee D; Macindo, John Rey B

2017-02-01

Clinical competence remains an issue in nursing and has received greater emphasis than academic competence. Although skill enhancement programs are recommended and beneficial, there is limited evidence on its influence on the clinical competence of pre-graduate nursing students. This study explored the attributes of a skills enhancement program that affect the perceived clinical competence of pre-graduate nursing students. A cross-sectional study was conducted in a private higher education institution in the Philippines from April to May 2016. A total of 245 pre-graduate nursing students participated and completed a three-part survey composed of the respondent's robotfoto, the Skills Enhancement Program Questionnaire, and the Clinical Competence Questionnaire. Factor analysis explicated the attributes of the skills enhancement program while structural equation modeling and path analysis analyzed the variables' relationship. Findings showed that a skills enhancement program has 4 attributes: supportive clinical instructor, comprehensive orientation, formative goals and objectives, and conducive learning environment. Although all attributes of the program positively affected clinical competence, a supportive clinical instructor had the strongest influence on all clinical competency dimensions. A skills enhancement program that has a supportive clinical instructor, comprehensive orientation, formative goals and objectives, and conducive learning environment facilitates clinical competency development among pre-graduate nursing students. This knowledge provides momentum for nursing educators to review and refine their skills and the existing design of their skills enhancement program to further develop clinical competency among pre-graduate nursing students. Copyright © 2016 Elsevier Ltd. All rights reserved.

77 FR 40072 - Assessment of the Program for Enhanced Review Transparency and Communication for New Molecular...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-06

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0603] Assessment of the Program for Enhanced Review Transparency and Communication for New Molecular Entity New... statement of work for an assessment of the Program for Enhanced Review Transparency and Communication for...

12 CFR 1805.102 - Relationship to other Fund programs.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Development Financial Institution from receiving assistance under this part. (b) Liquidity enhancement program. No entity that receives assistance through the liquidity enhancement program authorized under section...

Urban Extension's New Nontraditional Offering: Parent-Child Reading Enhancement Program

ERIC Educational Resources Information Center

Brandon, Dorothy P.; Tsamaase, Marea; Humphrey, Ronnie; Crenshaw, Kevin

2018-01-01

Urbanization is causing a major shift in Extension's programming throughout the United States. We present results of a nontraditional urban program (the Parent-Child Reading Enhancement Program) that is being implemented by Alabama Cooperative Extension System's Urban Affairs and New Nontraditional Programs unit. Findings suggest that this…

[Particle emission characteristics of diesel bus fueled with bio-diesel].

PubMed

Lou, Di-Ming; Chen, Feng; Hu, Zhi-Yuan; Tan, Pi-Qiang; Hu, Wei

2013-10-01

With the use of the Engine Exhaust Particle Sizer (EEPS), a study on the characteristics of particle emissions was carried out on a China-IV diesel bus fueled with blends of 5% , 10% , 20% , 50% bio-diesel transformed from restaurant waste oil and China-IV diesel (marked separately by BD5, BD10, BD20, BD50), pure bio-diesel (BD100) and pure diesel (BD0). The results indicated that particulate number (PN) and mass (PM) emissions of bio-diesel blends increased with the increase in bus speed and acceleration; with increasing bio-diesel content, particulate emissions displayed a relevant declining trend. In different speed ranges, the size distribution of particulate number emissions (PNSD) was bimodal; in different acceleration ranges, PNSD showed a gradual transition from bimodal shape to unimodal when bus operation was switched from decelerating to accelerating status. Bio-diesel blends with higher mixture ratios showed significant reduction in PN emissions for accumulated modes, and the particulate number emission peaks moved towards smaller sizes; but little change was obtained in PN emissions for nuclei modes; reduction also occurred in particle geometric diameter (Dg).

Influence of Propolis on Hygiene, Gingival Condition, and Oral Microflora in Patients with Cleft Lip and Palate Treated with Fixed Orthodontic Appliances

PubMed Central

Machorowska-Pieniążek, Agnieszka; Morawiec, Tadeusz; Tanasiewicz, Marta; Król, Wojciech

2013-01-01

The aim of this study was to evaluate the influence of 3% ethanol extract of propolis (EEP) on hygiene, gingival and microbiological status of oral cavity in patients with cleft lip and palate treated with fixed orthodontic appliances. The study included forty-one nonsyndromic complete unilateral of bilateral cleft lip and palate subjects with fixed appliance on at least 10 teeth. Twenty-one subjects were instructed to brush their teeth three times a day using toothpaste with propolis. Control group included twenty subjects who were asked to brush their teeth three times a day using a toothpaste without propolis. API, OPI, GI, and supragingival bacterial plaque were taken from each subject twice: baseline and after using the toothpaste for 35 days. The final examinations showed statistically significant decrease in OPI, GI, and the percentage of the Actinomyces spp. and Capnocytophaga spp. compared with baseline in propolis group subjects. The improvement in oral health in these patients confirms antibacterial, anti-inflammatory, and regenerative properties of propolis. PMID:23762106

Day treatment versus enhanced standard methadone services for opioid-dependent patients: a comparison of clinical efficacy and cost.

PubMed

Avants, S K; Margolin, A; Sindelar, J L; Rounsaville, B J; Schottenfeld, R; Stine, S; Cooney, N L; Rosenheck, R A; Li, S H; Kosten, T R

1999-01-01

This study examined the differential efficacy and relative costs of two intensities of adjunctive psychosocial services--a day treatment program and enhanced standard care--for the treatment of opioid-dependent patients maintained on methadone hydrochloride. A 12-week randomized clinical trial with 6-month follow-up was conducted in a community-based methadone maintenance program. Of the 308 patients who met inclusion criteria, 291 began treatment (day treatment program: N=145; enhanced standard care: N=146), and 237 completed treatment (82% of those assigned to the day treatment program and 81% of those receiving enhanced standard care). Two hundred twenty of the patients participated in the 6-month follow-up (75% of those in the day treatment program and 73% of those in enhanced standard care provided a follow-up urine sample for screening). Both interventions were 12 weeks in duration, manual-guided, and provided by master's-level clinicians. The day treatment was an intensive, 25-hour-per-week program. The enhanced standard care was standard methadone maintenance plus a weekly skills training group and referral to on- and off-site services. Outcome measures included twice weekly urine toxicology screens, severity of addiction-related problems, prevalence of HIV risk behaviors, and program costs. Although the cost of the day treatment program was significantly higher, there was no significant difference in the two groups' use of either opiates or cocaine. Over the course of treatment, drug use, drug-related problems, and HIV risk behaviors decreased significantly for patients assigned to both treatment intensities. Improvements were maintained at follow-up. Providing an intensive day treatment program to unemployed, inner-city methadone patients was not cost-effective relative to a program of enhanced methadone maintenance services, which produced comparable outcomes at less than half the cost.

Enhancing Digital Fluency through a Training Program for Creative Problem Solving Using Computer Programming

ERIC Educational Resources Information Center

Kim, SugHee; Chung, KwangSik; Yu, HeonChang

2013-01-01

The purpose of this paper is to propose a training program for creative problem solving based on computer programming. The proposed program will encourage students to solve real-life problems through a creative thinking spiral related to cognitive skills with computer programming. With the goal of enhancing digital fluency through this proposed…

34 CFR 611.2 - What management plan must be included in a Teacher Quality Enhancement Grants Program application?

Code of Federal Regulations, 2010 CFR

2010-07-01

... TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM General Provisions § 611.2 What management plan must be... 34 Education 3 2010-07-01 2010-07-01 false What management plan must be included in a Teacher Quality Enhancement Grants Program application? 611.2 Section 611.2 Education Regulations of the Offices...

4-H Youth Programs - Enhancing the Quality of Life.

ERIC Educational Resources Information Center

Pilat, Mary

Indiana 4-H Youth Programs are being used to enhance the quality of life for troubled adolescents in residential group homes and economically disadvantaged urban areas and to provide summer-school programs for children of migrant farm workers. Four basic types of program delivery modes exist in Indiana: clubs, junior leader program activities,…

Implementation cost analysis of a community-based exercise program for seniors in South Florida.

PubMed

Page, Timothy F; Batra, Anamica; Ghouse, Muddasir M; Palmer, Richard C

2014-07-01

The objective of the study was to measure the costs of implementing the EnhanceFitness program to elderly residents of South Florida. The Health Foundation of South Florida's Healthy Aging Regional Collaborative implemented EnhanceFitness as part of their initiative to make evidence-based healthy aging programs available to South Florida seniors. Cost data were collected from agencies participating in the delivery of EnhanceFitness classes in South Florida. Cost questionnaires were e-mailed to program coordinators from agencies participating in the delivery of EnhanceFitness classes. Program coordinators worked with accounting staff to complete the questionnaires. Questionnaires were returned via e-mail. Costs were presented from the perspective of participating agencies. Total costs were divided by the number of classes being offered by each agency to determine cost per class per month. Average monthly costs per class were $1,713 during the first year of implementation and $873 during the second year of implementation. The cost measurements, combined with information from the literature on cost savings attributable to EnhanceFitness participation, suggest that EnhanceFitness has the potential to generate a net societal cost savings among program participants. The results are useful for community agencies considering implementing EnhanceFitness for their populations. © 2014 Society for Public Health Education.

New global electron density observations from GPS-RO in the D- and E-Region ionosphere

NASA Astrophysics Data System (ADS)

Wu, Dong L.

2018-06-01

A novel retrieval technique is developed for electron density (Ne) in the D- and E-region (80-120 km) using the high-quality 50-Hz GPS radio occultation (GPS-RO) phase measurements. The new algorithm assumes a slow, linear variation in the F-region background when the GPS-RO passes through the D- and E-region, and extracts the Ne profiles at 80-130 km from the phase advance signal caused by Ne. Unlike the conventional Abel function, the new approach produces a sharp Ne weighting function in the lower ionosphere, and the Ne retrievals are in good agreement with the IRI (International Reference Ionosphere) model in terms of monthly maps, zonal means and diurnal variations. The daytime GPS-RO Ne profiles can be well characterized by the α-Chapman function of three parameters (NmE, hmE and H), showing that the bottom of E-region is deepening and sharpening towards the summer pole. At high latitudes the monthly GPS-RO Ne maps at 80-120 km reveal clear enhancement in the auroral zones, more prominent at night, as a result of energetic electron precipitation (EEP) from the outer radiation belt. The D-/E-region auroral Ne is strongly correlated with Kp on a daily basis. The new Ne data allow further comprehensive analyses of the sporadic E (Es) phenomena in connection with the background Ne in the E-region. The layered (2-10 km) and fluctuated (<2 km) Es components, namely Ne_Layer than Ne_Pert, are extracted with respect to the background Ne_Region on a profile-by-profile basis. The Ne_Layer component has a strong but highly-refined peak at ∼105 km, with an amplitude smaller than Ne_Region approximately by an order of magnitude. The Ne_Pert component, which was studied extensively in the past, is ∼2 orders of magnitude weaker than Ne_Layer. Both Ne_Layer and Ne_Pert are subject to significant diurnal and semidiurnal variations, showing downward progression with local time in amplitude. The 11-year solar cycle dominates the Ne interannual variations, showing larger Ne_Region and Ne_Layer but smaller Ne_Pert amplitudes in the solar maximum years. Enhanced Ne profiles are often observed in the polar winter, showing good correlation with solar proton events (SPEs) and geomagnetic activity. The new methodology offers great potential for retrieving low Ne in the D-region, where radio propagation and communication blackouts can occur due to enhanced ionization. For space weather applications it is recommended for GPS-RO operations to raise the top of high-rate data acquisition to ∼140 km in the future.

A Study of NSF Teacher Enhancement Program (TEP) Participants and Principal Investigators: 1984-1989. Volume I: Summary Report.

ERIC Educational Resources Information Center

Abt Associates, Inc., Cambridge, MA.

The National Science Foundation (NSF) supported more than 600 inservice teacher training programs between 1984 and 1989 under its Teacher Enhancement Program (TEP). Two studies were undertaken of TEP: the first was a survey of the 600 Principal Investigators (PIs) who had operated inservice teacher enhancement projects and the second, a survey of…

Seven Activities for Enhancing the Replicability of Evidence-Based Practices. Research-to-Results Brief. Publication #2007-30

ERIC Educational Resources Information Center

Metz, Allison J. R.; Bowie, Lillian; Blase, Karen

2007-01-01

This brief will define program replication, describe the critical role of "core components" in program replication, and outline seven activities that program developers and researchers can conduct to enhance the replicability of effective program models and facilitate their adoption by other organizations and programs. Outlined is seven specific…

75 FR 44 - Temporary Suspension of the Population Estimates and Income Estimates Challenge Programs

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-04

..., conduct research to enhance the estimates and challenge programs, and to integrate the updates from the... local governments would increase the administrative and evaluative complexity of this program for the... comparison with the population estimates, conducting research to enhance the estimates and challenge programs...

Nutrition Programs in the Workplace. WBGH Worksite Wellness Series.

ERIC Educational Resources Information Center

Glanz, Karen

As is the case with other worksite wellness programs, company-sponsored nutrition programs have been expanding both in numbers and in depth. Besides offering a convenient health-enhancing benefit to employees, worksite nutrition programs benefit business by preventing several costly nutrition-related health problems, enhancing employees' overall…

A study of extractive and remote-sensing sampling and measurement of emissions from military aircraft engines

NASA Astrophysics Data System (ADS)

Cheng, Meng-Dawn; Corporan, Edwin

2010-12-01

Aircraft emissions contribute to the increased atmospheric burden of particulate matter (PM) that plays an important role in air quality, human health, visibility, contrail formation and climate change. Sampling and measurement of modern aircraft emissions at the engine exhaust plane (EEP) for engine and fuel certification remains challenging, as no agency-certified method is available. In this paper we summarize the results of three recent field studies devoted to investigate the consistency and applicability of "extractive" and "optical remote-sensing" (ORS) technologies in the sampling and measurement of gaseous and PM emitted by a number of military aircraft engines. Three classes of military engines were investigated; these include T56, TF33, and T700 & T701C types of engines, which consume 70-80% of the military aviation fuel each year. JP-8 and Fischer-Tropsch (FT)-derived paraffinic fuels were used to study the effect of fuels. It was found that non-volatile particles in the engine emissions were in the 20 nm range for the low power condition of new helicopter engines to 80 nm for the high power condition of legacy engines. Elemental analysis indicated little metals were present on particles, while most of the materials on the exhaust particles were carbon and sulfate based. Alkanes, carbon monoxide, carbon dioxide, nitrogen oxides, sulfur dioxide, formaldehyde, ethylene, acetylene and propylene were detected. The last five species were most noticeable only under low engine power. The emission indices calculated based on the ORS data deviate significantly from those based on the extractive data. Nevertheless, the ORS techniques were useful in the sense that it provided non-intrusive real-time detection of species in the exhaust plume, which warrants further development. The results obtained in this program help validate sampling methodology and measurement techniques used for non-volatile PM aircraft emissions as described in the SAE AIR6037 (2009).

Development of NASA Technical Standards Program Relative to Enhancing Engineering Capabilities

NASA Technical Reports Server (NTRS)

Gill, Paul S.; Vaughan, William W.

2003-01-01

The enhancement of engineering capabilities is an important aspect of any organization; especially those engaged in aerospace development activities. Technical Standards are one of the key elements of this endeavor. The NASA Technical Standards Program was formed in 1997 in response to the NASA Administrator s directive to develop an Agencywide Technical Standards Program. The Program s principal objective involved the converting Center-unique technical standards into Agency wide standards and the adoption/endorsement of non-Government technical standards in lieu of government standards. In the process of these actions, the potential for further enhancement of the Agency s engineering capabilities was noted relative to value of being able to access Agencywide the necessary full-text technical standards, standards update notifications, and integration of lessons learned with technical standards, all available to the user from one Website. This was accomplished and is now being enhanced based on feedbacks from the Agency's engineering staff and supporting contractors. This paper addresses the development experiences with the NASA Technical Standards Program and the enhancement of the Agency's engineering capabilities provided by the Program s products. Metrics are provided on significant aspects of the Program.

Randomized Trial of Two Dissemination Strategies for a Skin Cancer Prevention Program in Aquatic Settings

PubMed Central

Escoffery, Cam; Elliott, Tom; Nehl, Eric J.

2015-01-01

Objectives. We compared 2 strategies for disseminating an evidence-based skin cancer prevention program. Methods. We evaluated the effects of 2 strategies (basic vs enhanced) for dissemination of the Pool Cool skin cancer prevention program in outdoor swimming pools on (1) program implementation, maintenance, and sustainability and (2) improvements in organizational and environmental supports for sun protection. The trial used a cluster-randomized design with pools as the unit of intervention and outcome. The enhanced group received extra incentives, reinforcement, feedback, and skill-building guidance. Surveys were collected in successive years (2003–2006) from managers of 435 pools in 33 metropolitan areas across the United States participating in the Pool Cool Diffusion Trial. Results. Both treatment groups improved their implementation of the program, but pools in the enhanced condition had significantly greater overall maintenance of the program over 3 summers of participation. Furthermore, pools in the enhanced condition established and maintained significantly greater sun-safety policies and supportive environments over time. Conclusions. This study found that more intensive, theory-driven dissemination strategies can significantly enhance program implementation and maintenance of health-promoting environmental and policy changes. Future research is warranted through longitudinal follow-up to examine sustainability. PMID:25521872

Effect of the Programmed Nutrition Beef Program on moisture retention of cooked ground beef patties and enhanced strip loins.

PubMed

2015-02-01

This study evaluated the influence of the Programmed Nutrition Beef Program and exogenous growth promotants (ExGP) on water holding capacity characteristics of enhanced beef strip loins. Sixty, frozen strip loins, arranged in a 2 × 2 factorial treatment arrangement with dietary program serving as the first factor and use of ExGP as the second factor, were thawed, injected with an enhancement solution, and stored for 7 days. Loins from ExGP cattle possessed the ability to bind more (P < 0.05) water before pumping and bind less (P < 0.05) water after pumping and storage. Loin pH across treatments was similar (P > 0.10) before injection, but increased post-injection and after storage (P < 0.01). Treatments did not affect loin purge loss, steak cook loss, and expressible moisture (P > 0.10). The Programmed Nutrition Beef Program and use of ExGPs minimally impacted water holding capacity of enhanced frozen/thawed beef strip loins.

7 CFR 625.4 - Program requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... activities that promote the restoration, protection, enhancement, maintenance, and management of forest... of successful restoration, enhancement, and protection of forest ecosystem functions and values when... AGRICULTURE WATER RESOURCES HEALTHY FORESTS RESERVE PROGRAM § 625.4 Program requirements. (a) General. Under...

External tank program productivity and quality enhancements - A case study

NASA Technical Reports Server (NTRS)

Locke, S. R.

1988-01-01

The optimization of the Manned Space Systems productivity and quality enhancement program is described. The guidelines and standards of the program and the roles played in it by various employee groups are addressed. Aspects of the program involving job/organization redefinition, production and planning in automation, and artificial intelligence and robotics are examined.

How a Personal Development Program Enhances Social Connection and Mobilises Women in the Community

ERIC Educational Resources Information Center

Spry, Nandila; Marchant, Teresa

2014-01-01

Gender equity and the empowerment of women is a significant international issue. Successful adult education programs are vital to enhance women's situation. Lessons learned from a personal development program provided for thousands of women are analysed. The program is conducted by community service providers in Australia and internationally, with…

Timber management planning with timber ram and goal programming

Treesearch

Richard C. Field

1978-01-01

By using goal programming to enhance the linear programming of Timber RAM, multiple decision criteria were incorporated in the timber management planning of a National Forest in the southeastern United States. Combining linear and goal programming capitalizes on the advantages of the two techniques and produces operationally feasible solutions. This enhancement may...

Terrain Mechanics and Modeling Research Program: Enhanced Vehicle Dynamics Module

DTIC Science & Technology

2009-05-01

ER D C/ G SL T R- 09 -8 Terrain Mechanics and Modeling Research Program Enhanced Vehicle Dynamics Module Daniel C. Creighton, George...public release; distribution is unlimited. Terrain Mechanics and Modeling Research Program ERDC/GSL TR-09-8 May 2009 Enhanced Vehicle Dynamics...Module Daniel C. Creighton, George B. McKinley, and Randolph A. Jones Geotechnical and Structures Laboratory U.S. Army Engineer Research and

78 FR 52899 - Supplemental Nutrition Assistance Program (SNAP) Enhancing Retail Food Store Eligibility...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-27

... DEPARTMENT OF AGRICULTURE Food and Nutrition Service Supplemental Nutrition Assistance Program (SNAP) Enhancing Retail Food Store Eligibility--Listening Sessions AGENCY: Food and Nutrition Service... for Information (RFI) published by FNS regarding Supplemental Nutrition Assistance Program (SNAP...

Life/Career Renewal: An Intervention for Vocational and Other Life Transitions.

ERIC Educational Resources Information Center

Robitschek, Christine

1997-01-01

A study examined the effectiveness of the Life/Career Renewal Program (LCR), a wilderness program for adults, in enhancing personal growth initiative (PGI) of 68 participants. Results support the hypothesis that the LCR program enhances PGI. (Author/JOW)

Kodak Skills Enhancement Program. U.S. Department of Education National Workplace Literacy Project. Final Report.

ERIC Educational Resources Information Center

Beaudin, Bart P.

The Kodak Skills Enhancement program was a workplace literacy project funded through the U.S. Department of Education's National Workplace Literacy Program. The project goals were as follows: (1) establish a positive climate within the Kodak corporate environment to ensure program effectiveness by garnering support at all levels; (2) determine the…

Equal Employment Opportunity Enhancement Program for Civilian Navy Employees: End of Fellowship Report

DTIC Science & Technology

1988-01-01

CTlr FILE copy2 EQUAL EMPLOYMENT OPPORTUNITY ENHANCEMENT PROGRAM FOR CIVILIAN NAVY EMPLOYEES: END OF FELLOWSHIP REPORT0 Lfl (V) Submitted by I Jack E...Specialization: Industrial/Organizational Psychology S8 12 21 o6o 3 EQUAL EMPLOYMENT OPPORTUNITY ENHANCEMENT PROGRAM FOR CIVILIAN NAVY EMPLOYEES: END OF...Problem Each Navy activity establishes equal employment opportunity (EEO) goals proportional to the racial/ethnic and gender composition of workers

The use of continuing adult education

NASA Technical Reports Server (NTRS)

Redd, Frank J.

1990-01-01

The objectives of the National Space Grant and Fellowship Program include the expansion of space-oriented educational programs beyond the traditional boundaries of university campuses to reach 'non-traditional' students whose personal and professional lives would be enhanced by access to such programs. These objectives coincide with those of the continuing education programs that exist on most university campuses. By utilizing continuing educations resources and facilities, members of the National Space Grant Program can greatly enhance the achievement of program objectives.

Using Bibliotherapy to Enhance Probation and Reduce Recidivism

ERIC Educational Resources Information Center

Schutt, Russell K.; Deng, Xiaogang; Stoehr, Taylor

2013-01-01

Prior research indicates that probation programs that include efforts to change cognitive orientations and social patterns can enhance their effectiveness. This article reports an evaluation of an enhanced probation program, Changing Lives Through Literature, which uses a form of bibliotherapy to increase its rehabilitative effect. Controlling for…

The Costs of an Enhanced Employee Assistance Program (EAP) Intervention.

ERIC Educational Resources Information Center

French, Michael T.; Dunlap, Laura J.; Zarkin, Gary A.; Karuntzos, Georgia T.

1998-01-01

This study estimates the economic costs of an enhanced Employee Assistance Program (EAP) intervention at a large midwestern EAP that serves 90 worksites. Results specify developmental and implementation costs and provide benchmark cost estimated for other EAPs that may be considering enhanced services. (SLD)

Redesigning Personnel Preparation: Lessons Learned and Considerations for Program Enhancement

ERIC Educational Resources Information Center

Little, Mary E.; Sobel, Donna; McCray, Erica D.; Wang, Jun

2015-01-01

Changing legal requirements, economic demands, accountability, and student demographics focus the need for reform among personnel preparation programs. Although redesign efforts in general and special education teacher preparation programs have increased, little evidence from research describes enhancement initiatives. In this article, the authors…

Effect of Mixing Enhancement Devices on Turbulence in Separate Flow Nozzles

NASA Technical Reports Server (NTRS)

Bridges, James

2001-01-01

This paper presents the effects of several mixing enhancement devices on turbulence in jet nozzles. The topics include: 1) The Advanced Subsonic Technology (AST) Program; 2) Test Programs SFNT97 and SFNT2K; 3) Facility; 4) Mixing Enhancement Nozzles; 5) IR reductions; 6) Schlieren of Chevrons; and 7) Aeroacoustics of Enhanced Mixing-Paradigm. This paper is presented in viewgraph form.

77 FR 71431 - New Agency Information Collection Activity Under OMB Review: Highway Baseline Assessment for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-30

... Collection Activity Under OMB Review: Highway Baseline Assessment for Security Enhancement (BASE) Program... Assessment for Security Enhancement (BASE) Program. Type of Request: New collection. OMB Control Number: Not yet assigned. Form(s): Highway Baseline Assessment for Security Enhancement (BASE). Affected Public...

34 CFR 611.1 - What definitions apply to the Teacher Quality Enhancement Grants Program?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 3 2012-07-01 2012-07-01 false What definitions apply to the Teacher Quality... Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM General Provisions § 611.1 What definitions apply to the Teacher Quality Enhancement...

34 CFR 611.1 - What definitions apply to the Teacher Quality Enhancement Grants Program?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 3 2014-07-01 2014-07-01 false What definitions apply to the Teacher Quality... Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM General Provisions § 611.1 What definitions apply to the Teacher Quality Enhancement...

34 CFR 611.1 - What definitions apply to the Teacher Quality Enhancement Grants Program?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 3 2011-07-01 2011-07-01 false What definitions apply to the Teacher Quality... Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM General Provisions § 611.1 What definitions apply to the Teacher Quality Enhancement...

Enhanced recovery pathways in thoracic surgery from Italian VATS group: nursing care program

PubMed Central

Loizzi, Domenico; Panariti, Silvana; Piccinin, Ivana; Sollitto, Francesco

2018-01-01

Enhanced recovery after surgery (ERAS) is an interprofessional program that can lead to hastened patient recovery and reduced time in hospital. Nursing staff play a key role in the implementation of enhanced recovery protocols. This issue focalizes the role of nurses in ERAS program for patients submitted to Thoracic Surgery, in particular for cases of major lung resection performed by a minimally invasive surgical approach (VATS, video assisted thoracic surgery). PMID:29629199

A 12-week commercial web-based weight-loss program for overweight and obese adults: randomized controlled trial comparing basic versus enhanced features.

PubMed

Collins, Clare E; Morgan, Philip J; Jones, Penelope; Fletcher, Kate; Martin, Julia; Aguiar, Elroy J; Lucas, Ashlee; Neve, Melinda J; Callister, Robin

2012-04-25

The development and use of Web-based programs for weight loss is increasing rapidly, yet they have rarely been evaluated using randomized controlled trials (RCTs). Interestingly, most people who attempt weight loss use commercially available programs, yet it is very uncommon for commercial programs to be evaluated independently or rigorously. To compare the efficacy of a standard commercial Web-based weight-loss program (basic) versus an enhanced version of this Web program that provided additional personalized e-feedback and contact from the provider (enhanced) versus a wait-list control group (control) on weight outcomes in overweight and obese adults. This purely Web-based trial using a closed online user group was an assessor-blinded RCT with participants randomly allocated to the basic or enhanced 12-week Web-based program, based on social cognitive theory, or the control, with body mass index (BMI) as the primary outcome. We enrolled 309 adults (129/309, 41.8% male, BMI mean 32.3, SD 4 kg/m(2)) with 84.1% (260/309) retention at 12 weeks. Intention-to-treat analysis showed that both intervention groups reduced their BMI compared with the controls (basic: -0.72, SD 1.1 kg/m(2), enhanced: -1.0, SD 1.4, control: 0.15, SD 0.82; P < .001) and lost significant weight (basic: -2.1, SD 3.3 kg, enhanced: -3.0, SD 4.1, control: 0.4, SD 2.3; P < .001) with changes in waist circumference (basic: -2.0, SD 3.5 cm, enhanced: -3.2, SD 4.7, control: 0.5, SD 3.0; P < .001) and waist-to-height ratio (basic: -0.01, SD 0.02, enhanced: -0.02, SD 0.03, control: 0.0, SD 0.02; P < .001), but no differences were observed between the basic and enhanced groups. The addition of personalized e-feedback and contact provided limited additional benefits compared with the basic program. A commercial Web-based weight-loss program can be efficacious across a range of weight-related outcomes and lifestyle behaviors and achieve clinically important weight loss. Although the provision of additional personalized feedback did not facilitate greater weight loss after 12 weeks, the impact of superior participant retention on longer-term outcomes requires further study. Further research is required to determine the optimal mix of program features that lead to the biggest treatment impact over time. Australian New Zealand Clinical Trials Registry (ANZCTR): 12610000197033.

Quality Enhancement: An Overview. Program Services Papers.

ERIC Educational Resources Information Center

North Carolina Partnership for Children, Raleigh.

Leading a series of in-depth technical assistance papers on improving the quality in early care and education programs, this brochure is designed to help local communities consider the most effective strategies in designing and implementing programs that improve child care quality. A quality enhancement approach is taken whereby communities begin…

Responsive Meta-Evaluation: A Participatory Approach to Enhancing Evaluation Quality

ERIC Educational Resources Information Center

Sturges, Keith M.; Howley, Caitlin

2017-01-01

In an era of ever-deepening budget cuts and a concomitant demand for substantiated programs, many organizations have elected to conduct internal program evaluations. Internal evaluations offer advantages (e.g., enhanced evaluator program knowledge and ease of data collection) but may confront important challenges, including credibility threats,…

Results of ENHANCED Implantable Cardioverter Defibrillator Programming to Reduce Therapies and Improve Quality of Life (from the ENHANCED-ICD Study).

PubMed

Mastenbroek, Mirjam H; Pedersen, Susanne S; van der Tweel, Ingeborg; Doevendans, Pieter A; Meine, Mathias

2016-02-15

Novel implantable cardioverter defibrillator (ICD) discrimination algorithms and programming strategies have significantly reduced the incidence of inappropriate shocks, but there are still gains to be made with respect to reducing appropriate but unnecessary antitachycardia pacing (ATP) and shocks. We examined whether programming a number of intervals to detect (NID) of 60/80 for ventricular tachyarrhythmia (VT)/ventricular fibrillation (VF) detection was safe and the impact of this strategy on (1) adverse events related to ICD shocks and syncopal events; (2) ATPs/shocks; and (3) patient-reported outcomes. The "ENHANCED Implantable Cardioverter Defibrillator programming to reduce therapies and improve quality of life" study (ENHANCED-ICD study) was a prospective, safety-monitoring study enrolling 60 primary and secondary prevention patients at the University Medical Center Utrecht. Patients implanted with any type of ICD with SmartShock technology and aged 18 to 80 years were eligible to participate. In all patients, a prolonged NID 60/80 was programmed. The cycle length for VT/fast VT/VF was 360/330/240 ms, respectively. Programming a NID 60/80 proved safe for ICD patients. Because of the new programming strategy, unnecessary ICD therapy was prevented in 10% of ENHANCED-ICD patients during a median follow-up period of 1.3 years. With respect to patient-reported outcomes, levels of distress were highest and perceived health status lowest at the time of implantation, which both gradually improved during follow-up. In conclusion, the ENHANCED-ICD study demonstrates that programming a NID 60/80 for VT/VF detection is safe for ICD patients and does not negatively impact their quality of life. Copyright © 2016 Elsevier Inc. All rights reserved.

Removal properties of diesel exhaust particles by a dielectric barrier discharge reactor.

PubMed

Suzuki, Ken-ichiro; Takeuchi, Naomi; Madokoro, Kazuhiko; Fushimi, Chihiro; Yao, Shuiliang; Fujioka, Yuichi; Nihei, Yoshimasa

2008-02-01

The removal properties of diesel exhaust particles (DEP) were investigated using an engine exhaust particle size spectrometer (EEPS), field emission-type scanning electron microscopy (FE-SEM) and time-of-flight secondary ion mass spectrometry (TOF-SIMS). DEP were treated using a dielectric barrier discharge (DBD) reactor installed in the tail pipe of a diesel engine, and a model DBD reactor fed with DEP in the mixture of N(2) and O(2). When changing the experimental parameters of both the plasma conditions and the engine load conditions, we obtained characteristic information of DEP treated with plasma discharges from the particle diameter and the composition. In evaluating the model DBD reactor, it became clear that there were two types of plasma processes (reactions with active oxygen species to yield CO(2) and reactions with active nitrogen species to yield nitrogen containing compounds). Moreover, from the result of a TOF-SIMS analysis, the characteristic secondary ions, such as C(2)H(6)N(+), C(4)H(12)N(+), and C(10)H(20)N(2)(+), were strongly detected from the DEP surfaces during the plasma discharges. This indicates that the nitrogen contained hydrocarbons were generated by plasma reactions.

Respiratory system mechanics during laparoscopic cholecystectomy.

PubMed

Rizzotti, L; Vassiliou, M; Amygdalou, A; Psarakis, Ch; Rasmussen, T R; Laopodis, V; Behrakis, P

2002-04-01

The influence of laparoscopic cholecystectomy (LC) on the mechanical properties of the respiratory system (RS) was examined using multiple regression analysis (MRA). Measurements of airway pressure (PaO) and flow (V') were obtained from 32 patients at four distinct stages of the LC procedure: 1) Immediately before the application of pneumoperitoneum (PP) at supine position, 2) 5 min after the induction of PP at Trendelenburg position, 3) 5 min after the patients position at reverse Trendelenburg, and 4) 5 min after the end ofthe surgical procedure with the patient again in supine position. Evaluated parameters were the RS elastance (Ers), resistance (Rrs), impedance (Zrs), the angle theta indicating the balance between the elastic and resistive components of the impedance, as well as the end-expiratory elastic recoil pressure (EEP). Ers and Zrs increased considerably during PP and remained elevated immediately after abolishing PP Rrs, on the contrary, returned to pre-operative levels right after the operation. Change of body position from Trendelenburg (T) to reverseTrendelenburg (rT) mainly induced a significant change in theta, thus indicating an increased dominance of the elastic component of Zrs on changing fromT to rT. There was no evidence of increased End-Expiratory Pressure during PP

An efficient system for the asymmetric acylation of (R,S)-3-n-butylphthalide catalyzed by novozyme 435.

PubMed

Li, Cuiqin; He, Laping; Qiu, Baoquan; Gao, Bing

2010-01-01

Novozyme 435 could be a highly efficient catalyst in the asymmetric acylation of (R,S)-3-n-butylphthalide in tetrahydrofuran-hexane solvents. The effect of various reaction parameters such as agitation velocity, water content, mixed media, temperature, concentration of Novozyme 435, molar ratio of acetic anhydride to (R,S)-3-n-butylphthalide, reaction time, enantiomeric excess of substrate (ee(S)), enantiomeric excess of product (ee(P)), and enantioselective ratio (E) were studied. Tetrahydrofuran markedly improved (R,S)-3-n-butylphthalide conversion, enantiomeric excess of remaining 3-n-butylphthalide, and enantiomeric ratio. The optimum media were 50% (v/v) tetrahydrofuran and 50% (v/v) hexane. Other ideal reaction conditions were an agitation velocity of 150 rpm, 0.4% (v/v) water content, temperature of 30 °C, 8 mg/mL dosage of Novozyme 435, 8:1 (0.4 mmol: 0.05 mmol) molar ratio of acetic anhydride to (R,S)-3-n-butylphthalide, and a reaction time of 48 hr. Under the optimum conditions, 96.4% ee(S) and 49.3% conversion of (R,S)-3-n-butylphthalide were achieved. In addition, enantiomeric excess of the product was above 98.0%.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Herraiz, Joaquin Lopez

Experimental coincidence cross section and transverse-longitudinal asymmetry ATL have been obtained for the quasielastic (e,e'p) reaction in 16O, 12C, and {sup 208}Pb in constant q-ω kinematics in the missing momentum range -350 < p miss < 350 MeV/c. In these experiments, performed in experimental Hall A of the Thomas Jefferson National Accelerator Facility (JLAB), the beam energy and the momentum and angle of the scattered electrons were kept fixed, while the angle between the proton momentum and the momentum transfer q was varied in order to map out the missing momentum distribution. The experimental cross section and A TL asymmetrymore » have been compared with Monte Carlo simulations based on Distorted Wave Impulse Approximation (DWIA) calculations with both relativistic and non-relativistic spinor structure. The spectroscopic factors obtained for both models are in agreement with previous experimental values, while A TL measurements favor the relativistic DWIA calculation. This thesis describes the details of the experimental setup, the calibration of the spectrometers, the techniques used in the data analysis to derive the final cross sections and the A TL, the ingredients of the theoretical calculations employed and the comparison of the results with the simulations based on these theoretical models.« less

Preparation and mechanical properties of layers made of recombinant spider silk proteins and silk from silk worm

NASA Astrophysics Data System (ADS)

Junghans, F.; Morawietz, M.; Conrad, U.; Scheibel, T.; Heilmann, A.; Spohn, U.

2006-02-01

Layers of recombinant spider silks and native silks from silk worms were prepared by spin-coating and casting of various solutions. FT-IR spectra were recorded to investigate the influence of the different mechanical stress occurring during the preparation of the silk layers. The solubility of the recombinant spider silk proteins SO1-ELP, C16, AQ24NR3, and of the silk fibroin from Bombyx mori were investigated in hexafluorisopropanol, ionic liquids and concentrated salt solutions. The morphology and thickness of the layers were determined by Atomic Force Microscopy (AFM) or with a profilometer. The mechanical behaviour was investigated by acoustic impedance analysis by using a quartz crystal microbalance (QCMB) as well as by microindentation. The density of silk layers (d<300 nm) was determined based on AFM and QCMB measurements. At silk layers thicker than 300 nm significant changes of the half-band-half width can be correlated with increasing energy dissipation. Microhardness measurements demonstrate that recombinant spider silk and sericine-free Bombyx mori silk layers achieve higher elastic penetration modules EEP and Martens hardness values HM than those of polyethylenterephthalate (PET) and polyetherimide (PEI) foils.

Probing the Repulsive Core of the Nucleon-Nucleon Interaction via the 4He(e,e`pN) Triple-Coincidence Reaction

DOE PAGES

Korover, Igor; Muangma, Navaphon; Hen, Or; ...

2014-07-01

We studied simultaneously the 4He(e,e'p), 4He(e,e'pp), and 4He(e,e'pn) reactions at Q 2=2 [GeV/c] 2 and x B >1, for a (e,e'p) missing-momentum range of 400 to 830 MeV/c. The knocked-out proton was detected in coincidence with a proton or neutron recoiling almost back to back to the missing momentum, leaving the residual A=2 system at low excitation energy. These data were used to identify two-nucleon short-range correlated pairs and to deduce their isospin structure as a function of missing momentum in a region where the nucleon-nucleon force is expected to change from predominantly tensor to repulsive. Neutron-proton pairs dominate themore » high-momentum tail of the nucleon momentum distributions, but their abundance is reduced as the nucleon momentum increases beyond ~500 MeV/c. The extracted fraction of proton-proton pairs is small and almost independent of the missing momentum in the range we studied. Our data are compared with ab-initio calculations of two-nucleon momentum distributions in 4He.« less

A Proposed Study Program for the Enhancement of Performance of Clocks in the DCS Timing system.

DTIC Science & Technology

1982-08-31

INTRODUCTION This technical note presents a proposed program of test and analysis with 𔃾 a goal of using prediction techniques to enhance the...future digital DCS and methods of satisfying them so that the reader will understand: (1) what is needed from this program to enhance the performance...over a number of years, using both simulation and analysis , have recommended that all major nodes of the DCS be referenced to Coordinated Universal Time

34 CFR 611.1 - What definitions apply to the Teacher Quality Enhancement Grants Program?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false What definitions apply to the Teacher Quality Enhancement Grants Program? 611.1 Section 611.1 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION TEACHER QUALITY ENHANCEMENT...

Career Skills Enhancement Program (CSEP). A National Workplace Literacy Program, Final Report To Cover Activities April 1, 1990-September 30, 1991.

ERIC Educational Resources Information Center

Gray, Brenda

The Career Skills Enhancement Program (CSEP) was a National Workplace Literacy Program offered to Santa Clara County (California) Office of Education (COE) employees. A job skills study involved personal interviews, job shadowing, and examination of job descriptions and materials used by employees. Based on the study and initial needs assessment,…

The enhanced forest inventory and analysis program of the USDA forest service: historical perspective and announcements of statistical documentation

Treesearch

Ronald E. McRoberts; William A. Bechtold; Paul L. Patterson; Charles T. Scott; Gregory A. Reams

2005-01-01

The Forest Inventory and Analysis (FIA) program of the USDA Forest Service has initiated a transition from regional, periodic inventories to an enhanced national FIA program featuring annual measurement of a proportion of plots in each state, greater national consistency, and integration with the ground sampling component of the Forest Health Monitoring (FHM) program...

Understanding science teacher enhancement programs: Essential components and a model

NASA Astrophysics Data System (ADS)

Spiegel, Samuel Albert

Researchers and practioners alike recognize that "the national goal that every child in the United States has access to high-quality school education in science and mathematics cannot be realized without the availability of effective professional development of teachers" (Hewson, 1997, p. 16). Further, there is a plethora of reports calling for the improvement of professional development efforts (Guskey & Huberman, 1995; Kyle, 1995; Loucks-Horsley, Hewson, Love, & Stiles, 1997). In this study I analyze a successful 3-year teacher enhancement program, one form of professional development, to: (1) identify essential components of an effective teacher enhancement program; and (2) create a model to identify and articulate the critical issues in designing, implementing, and evaluating teacher enhancement programs. Five primary sources of information were converted into data: (1) exit questionnaires, (2) exit surveys, (3) exit interview transcripts, (4) focus group transcripts, and (5) other artifacts. Additionally, a focus group was used to conduct member checks. Data were analyzed in an iterative process which led to the development of the list of essential components. The Components are categorized by three organizers: Structure (e.g., science research experience, a mediator throughout the program), Context (e.g., intensity, collaboration), and Participant Interpretation (e.g., perceived to be "safe" to examine personal beliefs and practices, actively engaged). The model is based on: (1) a 4-year study of a successful teacher enhancement program; (2) an analysis of professional development efforts reported in the literature; and (3) reflective discussions with implementors, evaluators, and participants of professional development programs. The model consists of three perspectives, cognitive, symbolic interaction, and organizational, representing different viewpoints from which to consider issues relevant to the success of a teacher enhancement program. These perspectives influence and are examined across three settings, program, individual, and school. An over-arching theme, namely the content focus of the program, such as the teaching and learning of science illuminate both the perspectives and the settings. While the model was developed to understand and evaluate a specific program, it is hypothesized that it can be a powerful tool for designing and implementing a variety of programs.

Expression of Terminal Effector Genes in Mammalian Neurons Is Maintained by a Dynamic Relay of Transient Enhancers.

PubMed

Rhee, Ho Sung; Closser, Michael; Guo, Yuchun; Bashkirova, Elizaveta V; Tan, G Christopher; Gifford, David K; Wichterle, Hynek

2016-12-21

Generic spinal motor neuron identity is established by cooperative binding of programming transcription factors (TFs), Isl1 and Lhx3, to motor-neuron-specific enhancers. How expression of effector genes is maintained following downregulation of programming TFs in maturing neurons remains unknown. High-resolution exonuclease (ChIP-exo) mapping revealed that the majority of enhancers established by programming TFs are rapidly deactivated following Lhx3 downregulation in stem-cell-derived hypaxial motor neurons. Isl1 is released from nascent motor neuron enhancers and recruited to new enhancers bound by clusters of Onecut1 in maturing neurons. Synthetic enhancer reporter assays revealed that Isl1 operates as an integrator factor, translating the density of Lhx3 or Onecut1 binding sites into transient enhancer activity. Importantly, independent Isl1/Lhx3- and Isl1/Onecut1-bound enhancers contribute to sustained expression of motor neuron effector genes, demonstrating that outwardly stable expression of terminal effector genes in postmitotic neurons is controlled by a dynamic relay of stage-specific enhancers. Copyright © 2016 Elsevier Inc. All rights reserved.

75 FR 55806 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Patient...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-14

... Care Act (PPACA), Emerging Infections Program (EIP), Enhancing Epidemiology and Laboratory Capacity... (PPACA), Emerging Infections Program (EIP), Enhancing Epidemiology and Laboratory Capacity, Funding...

Evaluation of a Digital Game-Based Learning Program for Enhancing Youth Mental Health: A Structural Equation Modeling of the Program Effectiveness.

PubMed

Huen, Jenny My; Lai, Eliza Sy; Shum, Angie Ky; So, Sam Wk; Chan, Melissa Ky; Wong, Paul Wc; Law, Y W; Yip, Paul Sf

2016-10-07

Digital game-based learning (DGBL) makes use of the entertaining power of digital games for educational purposes. Effectiveness assessment of DGBL programs has been underexplored and no attempt has been made to simultaneously model both important components of DGBL: learning attainment (ie, educational purposes of DGBL) and engagement of users (ie, entertaining power of DGBL) in evaluating program effectiveness. This study aimed to describe and evaluate an Internet-based DGBL program, Professor Gooley and the Flame of Mind, which promotes mental health to adolescents in a positive youth development approach. In particular, we investigated whether user engagement in the DGBL program could enhance their attainment on each of the learning constructs per DGBL module and subsequently enhance their mental health as measured by psychological well-being. Users were assessed on their attainment on each learning construct, psychological well-being, and engagement in each of the modules. One structural equation model was constructed for each DGBL module to model the effect of users' engagement and attainment on the learning construct on their psychological well-being. Of the 498 secondary school students that registered and participated from the first module of the DGBL program, 192 completed all 8 modules of the program. Results from structural equation modeling suggested that a higher extent of engagement in the program activities facilitated users' attainment on the learning constructs on most of the modules and in turn enhanced their psychological well-being after controlling for users' initial psychological well-being and initial attainment on the constructs. This study provided evidence that Internet intervention for mental health, implemented with the technologies and digital innovations of DGBL, could enhance youth mental health. Structural equation modeling is a promising approach in evaluating the effectiveness of DGBL programs.

A Program to Enhance Self-Concept of Junior High Students.

ERIC Educational Resources Information Center

McMillan, James H.

This research analyzes the results of a program to enhance the self concepts of junior high students. Subjects were 80 students identified as having low self concepts. They participated in an eight-week program to develop skills in personal and social awareness. Pretest posttest scores on the Coopersmith Self-Esteem Inventory indicated that…

An outdoor challenge program as a means of enhancing mental health

Treesearch

Robert A. Hanson

1977-01-01

Modern life fosters confusion and encourages passivity, and youth suffer most from this pattern. The Outdoor Challenge Program enables young people to experience the active roles and the clarity of purpose called forth by a wilderness opportunity. The experience appears to enhance their mental health during and after the program.

Evaluation of Parent and Child Enhancement (PACE) Program: Randomized Controlled Trial

ERIC Educational Resources Information Center

Leung, Cynthia; Tsang, Sandra; Lo, Cyrus

2017-01-01

Objective: This study examined the efficacy of the Parent and Child Enhancement (PACE) program on child learning, child behavior problems, and parental stress, using randomized controlled trial design, in social services centers. Methods: Eligibility criteria were (1) children aged 2 years at program commencement, (2) low-income, new immigrant, or…

Development of Education Programs in Mountainous Regions to Enhance the Culture and Knowledge of Minority Nationalities.

ERIC Educational Resources Information Center

Wei, Shiyuan; Zhou, Guangda

1989-01-01

Describes the historical development of educational programs which could enhance the culture and knowledge of minorities in the mountainous regions of China. Identifies current major problems in minority education and lists statistical information for the school population. Provides guidelines for developing a minority education program. (KO)

Enhancing HIV Communication between Parents and Children: Efficacy of the Parents Matter! Program

ERIC Educational Resources Information Center

Miller, Kim S.; Lin, Carol Y.; Poulsen, Melissa N.; Fasula, Amy; Wyckoff, Sarah C.; Forehand, Rex; Long, Nicholas; Armistead, Lisa

2011-01-01

We examine efficacy of the Parents Matter! Program (PMP), a program to teach African-American parents of preadolescents sexual communication and HIV-prevention skills, through a multicenter, randomized control trial. A total of 1115 parent-child participants were randomized to one of three intervention arms (enhanced, brief, control). Percentages…

Development of a Training Program for Enhancement of Technology Competencies of University Lecturers

ERIC Educational Resources Information Center

Cruthaka, Chomsupak; Pinngern, Ouen

2016-01-01

The objectives were: (1) the components of the technology competencies of university lecturers were studied. The researchers also described and analyzed (2) the development of a training program for enhancement of the technology competencies of these lecturers. Also, the researchers evaluated (3) the program they had constructed. The sample…

The Skills Enhancement Training Program. Performance Report.

ERIC Educational Resources Information Center

Food and Beverage Workers Union, Local 32, Washington, DC.

This report describes a joint labor-management workplace literacy program called SET (Skills Enhancement Training) that targeted the more than 2,000 unionized employees of food service contractors at U.S. government institutions in Washington, D.C. Nineteen classes were offered and a total of 191 people self-selected themselves into the program.…

Portfolio optimization in enhanced index tracking with goal programming approach

NASA Astrophysics Data System (ADS)

Siew, Lam Weng; Jaaman, Saiful Hafizah Hj.; Ismail, Hamizun bin

2014-09-01

Enhanced index tracking is a popular form of passive fund management in stock market. Enhanced index tracking aims to generate excess return over the return achieved by the market index without purchasing all of the stocks that make up the index. This can be done by establishing an optimal portfolio to maximize the mean return and minimize the risk. The objective of this paper is to determine the portfolio composition and performance using goal programming approach in enhanced index tracking and comparing it to the market index. Goal programming is a branch of multi-objective optimization which can handle decision problems that involve two different goals in enhanced index tracking, a trade-off between maximizing the mean return and minimizing the risk. The results of this study show that the optimal portfolio with goal programming approach is able to outperform the Malaysia market index which is FTSE Bursa Malaysia Kuala Lumpur Composite Index because of higher mean return and lower risk without purchasing all the stocks in the market index.

Mentoring Program Enhancements Supporting Effective Mentoring of Children of Incarcerated Parents.

PubMed

Stump, Kathryn N; Kupersmidt, Janis B; Stelter, Rebecca L; Rhodes, Jean E

2018-04-26

Children of incarcerated parents (COIP) are at risk for a range of negative outcomes; however, participating in a mentoring relationship can be a promising intervention for these youth. This study examined the impact of mentoring and mentoring program enhancements on COIP. Secondary data analyses were conducted on an archival database consisting of 70,729 matches from 216 Big Brothers Big Sisters (BBBS) local agencies to establish the differential effects of mentoring on COIP. A subset of 45 BBBS agencies, representing 25,252 matches, participated in a telephone interview about program enhancements for better serving COIP. Results revealed that enhanced program practices, including having specific program goals, providing specialized mentor training, and receiving additional funding resulted in better outcomes for COIP matches. Specifically, specialized mentor training and receiving additional funding for serving matches containing COIP were associated with longer and stronger matches. Having specific goals for serving COIP was associated with higher educational expectations in COIP. Results are discussed in terms of benefits of a relationship-based intervention for addressing the needs of COIP and suggestions for program improvements when mentoring programs are serving this unique population of youth. © Society for Community Research and Action 2018.

75 FR 39033 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Patient...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-07

... Care Act (PPACA), Emerging Infections Program (EIP), Enhancing Epidemiology and Laboratory Capacity... Program (EIP), Enhancing Epidemiology and Laboratory Capacity, Funding Opportunity Announcement FOA CI10...

Pilot Evaluation of Parent and Child Enhancement Program for Disadvantaged Families

ERIC Educational Resources Information Center

Leung, Cynthia; Tsang, Sandra; Leung, Iona

2014-01-01

Objective: The present study was a pilot evaluation of the effectiveness of the Parent and Child Enhancement (PACE) program in enhancing child development for disadvantaged families with children aged 2 to 3. Method: Participants included 23 parent-child dyads who attended 2-hr sessions twice weekly for 20 weeks. Parents and children were assessed…

Does State Aid Stimulate Public Library Expenditures? Evidence from Pennsylvania's Enhancement Aid Program

ERIC Educational Resources Information Center

Stine, William F.

2006-01-01

Pennsylvania public libraries began receiving increased allotments of state aid in 2000. In the first two years of enhancement aid, total state aid received by Pennsylvania libraries more than doubled. This reversed the trend of little growth in the years preceding 2000. The enhancement aid program also redesigned certain categories of state aid…

Desert Survivors: The Design and Implementation of a Television Program to Enhance Local Scientific Literacy

ERIC Educational Resources Information Center

Utz, Jenifer C.; Rausch, Candice M.; Fruth, Laurie; Thomas, Megan E.; van Breukelen, Frank

2007-01-01

Outreach efforts by faculty members are oftentimes limited in scope due to hectic schedules. We developed a program to enhance science literacy in elementary school children that allows experts to reach a tremendous audience while minimizing their time commitment. The foundation of the program is a television series entitled "Desert Survivors."…

The Effectiveness of Pre-Service Principal Preparation Programs on Instructional School Leadership in High-Stakes Testing Grades

ERIC Educational Resources Information Center

Pinder, Glen T.

2017-01-01

In today's world of accountability, the preparation of school leaders has never been more critical. Many states are now developing policies and processes that seek to enhance school leadership preparation programs. Enhancing school leadership preparation programs is particularly important in the area of instructional leadership because research…

The Impact of an Outdoor Orientation Program on First-Year Student Perceptions of Life Effectiveness and Campus Integration

ERIC Educational Resources Information Center

Lathrop, Anna H.; O'Connell, Timothy S.; Howard, Ryan A.

2012-01-01

Although outdoor orientation programs, as a special type of orientation designed to enhance student retention, are relatively commonplace in the United States - we are not aware of any such campuswide initiatives in Canada. Research indicates that outdoor orientation programs impact students in a positive way, enhancing academic success, personal…

15 CFR 923.122 - Objectives.

Code of Federal Regulations, 2011 CFR

2011-01-01

... coastal zone enhancement objective means any of the following objectives: (1) Protection, restoration, or... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Coastal Zone Enhancement Grants Program § 923.122 Objectives. (a...

15 CFR 923.122 - Objectives.

Code of Federal Regulations, 2010 CFR

2010-01-01

... coastal zone enhancement objective means any of the following objectives: (1) Protection, restoration, or... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Coastal Zone Enhancement Grants Program § 923.122 Objectives. (a...

15 CFR 923.122 - Objectives.

Code of Federal Regulations, 2014 CFR

2014-01-01

... coastal zone enhancement objective means any of the following objectives: (1) Protection, restoration, or... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Coastal Zone Enhancement Grants Program § 923.122 Objectives. (a...

15 CFR 923.122 - Objectives.

Code of Federal Regulations, 2013 CFR

2013-01-01

... coastal zone enhancement objective means any of the following objectives: (1) Protection, restoration, or... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Coastal Zone Enhancement Grants Program § 923.122 Objectives. (a...

15 CFR 923.122 - Objectives.

Code of Federal Regulations, 2012 CFR

2012-01-01

... coastal zone enhancement objective means any of the following objectives: (1) Protection, restoration, or... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Coastal Zone Enhancement Grants Program § 923.122 Objectives. (a...

Enhancing outreach for persons with serious mental illness: 12-month results from a cluster randomized trial of an adaptive implementation strategy.

PubMed

Kilbourne, Amy M; Almirall, Daniel; Goodrich, David E; Lai, Zongshan; Abraham, Kristen M; Nord, Kristina M; Bowersox, Nicholas W

2014-12-28

Few implementation strategies have been empirically tested for their effectiveness in improving uptake of evidence-based treatments or programs. This study compared the effectiveness of an immediate versus delayed enhanced implementation strategy (Enhanced Replicating Effective Programs (REP)) for providers at Veterans Health Administration (VA) outpatient facilities (sites) on improved uptake of an outreach program (Re-Engage) among sites not initially responding to a standard implementation strategy. One mental health provider from each U.S. VA site (N = 158) was initially given a REP-based package and training program in Re-Engage. The Re-Engage program involved giving each site provider a list of patients with serious mental illness who had not been seen at their facility for at least a year, requesting that providers contact these patients, assessing patient clinical status, and where appropriate, facilitating appointments to VA health services. At month 6, sites considered non-responsive (N = 89, total of 3,075 patients), defined as providers updating documentation for less than <80% of patients on their list, were randomized to two adaptive implementation interventions: Enhanced REP (provider coaching; N = 40 sites) for 6 months followed by Standard REP for 6 months; versus continued Standard REP (N = 49 sites) for 6 months followed by 6 months of Enhanced REP for sites still not responding. Outcomes included patient-level Re-Engage implementation and utilization. Patients from sites that were randomized to receive Enhanced REP immediately compared to Standard REP were more likely to have a completed contact (adjusted OR = 2.13; 95% CI: 1.09-4.19, P = 0.02). There were no differences in patient-level utilization between Enhanced and Standard REP sites. Enhanced REP was associated with greater Re-Engage program uptake (completed contacts) among sites not responding to a standard implementation strategy. Further research is needed to determine whether national implementation of Facilitation results in tangible changes in patient-level outcomes. ISRCTN21059161.

Personal Benefits of a Health Evaluation and Enhancement Program

NASA Technical Reports Server (NTRS)

Heinzelmann, F.; Durbeck, D. C.

1970-01-01

A study was made of the benefits reported by participants in a health evaluation and enhancement program dealing with physical activity. Program benefits were identified and defined in regard to three major areas: program effects on work; program effects on health; and program effects on habits and behavior. A strong positive and consistent relationship was found between reported benefits in each of these areas and measures of improvement in cardiovascular functioning based on treadmill performance. Significant differences in these measures of improvement were also found between participants who reported program benefits and those persons who did not. These findings provide a meaningful profile of the pattern of benefits generated by this kind of health program.

The Impact of Preservice Teachers' Experiences in a Video-Enhanced Training Program on Their Teaching: A Case Study in Physical Education

ERIC Educational Resources Information Center

Gaudin, Cyrille; Chaliès, Sébastien; Amathieu, Jérôme

2018-01-01

This case study documents the influence of preservice teachers' experiences in a Video-Enhanced Training Program (VETP) on their teaching. The conceptual framework of this VETP comes from a research program in cultural anthropology based on Wittgenstein's analytical philosophy. Influence was identified during self-confrontation interviews with…

Department of Homeland Security Assistance to States and Localities: A Summary and Issues for the 111th Congress

DTIC Science & Technology

2009-12-01

6 Intercity Passenger Rail Program (Amtrak) .....................................................................7 Intercity Bus Security Grant...20 Additionally Amtrak is eligible to receive funding to continue security enhancements for its intercity rail services between high-risk urban...Research Service 7 Intercity Passenger Rail Program (Amtrak) The Intercity Passenger Rail Program (IPR) is designed to enhance security of the

Learning Program for Enhancing Visual Literacy for Non-Design Students Using a CMS to Share Outcomes

ERIC Educational Resources Information Center

Ariga, Taeko; Watanabe, Takashi; Otani, Toshio; Masuzawa, Toshimitsu

2016-01-01

This study proposes a basic learning program for enhancing visual literacy using an original Web content management system (Web CMS) to share students' outcomes in class as a blog post. It seeks to reinforce students' understanding and awareness of the design of visual content. The learning program described in this research focuses on to address…

The Bodenmann Couples Coping Enhancement Training (CCET): A New Approach to Prevention of Marital Distress Based upon Stress and Coping

ERIC Educational Resources Information Center

Bodenmann, Guy; Shantinath, S. D.

2004-01-01

We describe a distress prevention training program for couples and three empirical studies that support its effectiveness. The program, Couples Coping Enhancement Training (CCET), is based both upon stress and coping theory and research on couples. In addition to traditional elements of couples programs (e.g., communication and problem-solving…

Does Parental Attributional Retraining and Anger Management Enhance the Effects of the Triple P-Positive Parenting Program with Parents at Risk of Child Maltreatment?

ERIC Educational Resources Information Center

Sanders, Matthew R.; Pidgeon, Aileen M.; Gravestock, Fred; Connors, Mark D.; Brown, Samantha; Young, Ross W.

2004-01-01

Ninety-eight parents experiencing significant difficulties in managing their own anger in their interactions with their preschool-aged children were randomly assigned either to an enhanced group-administered behavioral family intervention program based on the Triple P-Positive Parenting Program that incorporated attributional retraining and anger…

Enhancing a Career Exploration Program for 8th Grade Students with an Assessment for the Multiple Intelligences.

ERIC Educational Resources Information Center

Shearer, C. Branton

The use of a multiple intelligences (MI) assessment to enhance a career exploration program for eighth graders was studied. All of the eighth graders (n=160) in a suburban middle school completed three sets of activities as part of their career exploration program. Students completed a multiple intelligences self-assessment, the Multiple…

Development of a Program to Enhance Curriculum and Learning Management Competency of Private Primary School Teachers

ERIC Educational Resources Information Center

Panichpongsapak, Ratthasart; Tesaputa, Kowat; Sri-ampai, Anan

2016-01-01

The aims of this research were: (1) to study the factors and indicators to enhance curriculum and learning management competency of private primary school teachers; (2) to study current situations and desirable situations and techniques; (3) to develop a program; and (4) to study the effects of a program. The study comprised 4 phases: Phase…

7 CFR 662.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

.... These programs include: Conservation Stewardship Program, Farm and Ranch Lands Protection Program, Grassland Reserve Program, Environmental Quality Incentives Program, Conservation Innovation Grants, Agricultural Water Enhancement Program, Conservation of Private Grazing Land, Wildlife Habitat Incentive...

Mindfulness-Based Cognitive Approach for Seniors (MBCAS): Program Development and Implementation.

PubMed

Zellner Keller, Brigitte; Singh, Nirbhay N; Winton, Alan S W

2014-01-01

A number of cognitive interventions have been developed to enhance cognitive functioning in the growing population of the elderly. We describe the Mindfulness-Based Cognitive Approach for Seniors (MBCAS), a new training program designed especially for seniors. It was conceived in the context of self-development for seniors who wish to enhance their relationship with their inner and outer selves in order to navigate their aging process more easily and fluently. Physical and psychosocial problems related to aging, as well as some temporal issues, were taken into account in developing this program. Unlike clinically oriented mindfulness-based programs, which are generally delivered during an 8-week period, the MBCAS training program is presented over a period of 8 months. The main objectives of this program are to teach seniors to observe current experiences with nonjudgmental awareness, to identify automatic behaviors or reactions to current experiences that are potentially nonadaptive, and to enhance and reinforce positive coping with typical difficulties that they face in their daily lives. Details of the program development and initial implementation are presented, with suggestions for evaluating the program's effectiveness.

76 FR 18538 - Applications for New Awards; National Professional Development Program

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-04

... DEPARTMENT OF EDUCATION [CFDA 84.195N] Applications for New Awards; National Professional Development Program AGENCY: Office of English Language Acquisition, Language Enhancement, and Academic... Language Acquisition, Language Enhancement and Academic Achievement for Limited English Proficient Students...

Use of commercial grade item dedication to reduce procurement costs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosch, F.

1995-09-01

In the mid-1980s, the Nuclear Regulatory Industry (NRC) began inspecting utility practices of procuring and dedicating commercial grade items intended for plant safety-related applications. As a result of the industry efforts to address NRC concerns, nuclear utilities have enhanced existing programs and procedures for dedication of commercial grade items. Though these programs were originally enhanced to meet NRC concerns, utilities have discovered that the dedication of commercial grade items can also reduce overall procurement costs. This paper will discuss the enhancement of utility dedication programs and demonstrates how utilities have utilized them to reduce procurement costs.

ENHANCING RESEARCH ETHICS REVIEW SYSTEMS IN EGYPT: THE FOCUS OF AN INTERNATIONAL TRAINING PROGRAM INFORMED BY AN ECOLOGICAL DEVELOPMENTAL APPROACH TO ENHANCING RESEARCH ETHICS CAPACITY

PubMed Central

Edwards, Hillary Anne; Hifnawy, Tamer; Silverman, Henry

2014-01-01

Recently, training programs in research ethics have been established to enhance individual and institutional capacity in research ethics in the developing world. However, commentators have expressed concern that the efforts of these training programs have placed “too great an emphasis on guidelines and research ethics review”, which will have limited effect on ensuring ethical conduct in research. What is needed instead is a culture of ethical conduct supported by national and institutional commitment to ethical practices that are reinforced by upstream enabling conditions (strong civil society, public accountability, and trust in basic transactional processes), which are in turn influenced by developmental conditions (basic freedoms of political freedoms, economic facilities, social opportunities, transparency guarantees, and protective security). Examining this more inclusive understanding of the determinants of ethical conduct enhances at once both an appreciation of the limitations of current efforts of training programs in research ethics and an understanding of what additional training elements are needed to enable trainees to facilitate national and institutional policy changes that enhance research practices. We apply this developmental model to a training program focused in Egypt to describe examples of such additional training activities. PMID:24894063

Enhancing Research Ethics Review Systems in Egypt: The Focus of an International Training Program Informed by an Ecological Developmental Approach to Enhancing Research Ethics Capacity.

PubMed

Edwards, Hillary Anne; Hifnawy, Tamer; Silverman, Henry

2015-12-01

Recently, training programs in research ethics have been established to enhance individual and institutional capacity in research ethics in the developing world. However, commentators have expressed concern that the efforts of these training programs have placed 'too great an emphasis on guidelines and research ethics review', which will have limited effect on ensuring ethical conduct in research. What is needed instead is a culture of ethical conduct supported by national and institutional commitment to ethical practices that are reinforced by upstream enabling conditions (strong civil society, public accountability, and trust in basic transactional processes), which are in turn influenced by developmental conditions (basic freedoms of political freedoms, economic facilities, social opportunities, transparency guarantees, and protective security). Examining this more inclusive understanding of the determinants of ethical conduct enhances at once both an appreciation of the limitations of current efforts of training programs in research ethics and an understanding of what additional training elements are needed to enable trainees to facilitate national and institutional policy changes that enhance research practices. We apply this developmental model to a training program focused in Egypt to describe examples of such additional training activities. © 2014 John Wiley & Sons Ltd.

Evaluation of a Digital Game-Based Learning Program for Enhancing Youth Mental Health: A Structural Equation Modeling of the Program Effectiveness

PubMed Central

Huen, Jenny MY; Lai, Eliza SY; Shum, Angie KY; So, Sam WK; Chan, Melissa KY; Wong, Paul WC; Law, YW

2016-01-01

Background Digital game-based learning (DGBL) makes use of the entertaining power of digital games for educational purposes. Effectiveness assessment of DGBL programs has been underexplored and no attempt has been made to simultaneously model both important components of DGBL: learning attainment (ie, educational purposes of DGBL) and engagement of users (ie, entertaining power of DGBL) in evaluating program effectiveness. Objective This study aimed to describe and evaluate an Internet-based DGBL program, Professor Gooley and the Flame of Mind, which promotes mental health to adolescents in a positive youth development approach. In particular, we investigated whether user engagement in the DGBL program could enhance their attainment on each of the learning constructs per DGBL module and subsequently enhance their mental health as measured by psychological well-being. Methods Users were assessed on their attainment on each learning construct, psychological well-being, and engagement in each of the modules. One structural equation model was constructed for each DGBL module to model the effect of users' engagement and attainment on the learning construct on their psychological well-being. Results Of the 498 secondary school students that registered and participated from the first module of the DGBL program, 192 completed all 8 modules of the program. Results from structural equation modeling suggested that a higher extent of engagement in the program activities facilitated users’ attainment on the learning constructs on most of the modules and in turn enhanced their psychological well-being after controlling for users’ initial psychological well-being and initial attainment on the constructs. Conclusions This study provided evidence that Internet intervention for mental health, implemented with the technologies and digital innovations of DGBL, could enhance youth mental health. Structural equation modeling is a promising approach in evaluating the effectiveness of DGBL programs. PMID:27717921

The Evaluation of Enhanced Academic Instruction in After-School Programs: Findings After the First Year of Implementation. NCEE 2008-4021

ERIC Educational Resources Information Center

Black, Alison Rebeck; Doolittle, Fred; Zhu, Pei; Unterman, Rebecca; Grossman, Jean Baldwin

2008-01-01

This report presents findings, after one year of program implementation, from the Evaluation of Enhanced Academic Instruction in After-School Programs--a two-year intervention and random assignment evaluation of adapted models of regular-school-day math and reading instruction in after-school settings for students in grades 2 through 5. This…

Does Family Make a Difference? Mid-Term Effects of a School/Home-Based Intervention Program to Enhance Reading Motivation

ERIC Educational Resources Information Center

Villiger, Caroline; Niggli, Alois; Wandeler, Christian; Kutzelmann, Sabine

2012-01-01

This study examined the effects of a school/home-based intervention program designed to enhance the reading motivation and comprehension of Swiss fourth graders (N = 713). In order to identify the specific contribution of the home environment, the program was implemented in one group "without" (N = 244) and in one group "with"…

Compulsory Project-Level Involvement and the Use of Program-Level Evaluations: Evaluating the Local Systemic Change for Teacher Enhancement Program

ERIC Educational Resources Information Center

Johnson, Kelli; Weiss, Iris R.

2011-01-01

In 1995, the National Science Foundation (NSF) contracted with principal investigator Iris Weiss and an evaluation team at Horizon Research, Inc. (HRI) to conduct a national evaluation of the Local Systemic Change for Teacher Enhancement program (LSC). HRI conducted the core evaluation under a $6.25 million contract with NSF. This program…

Behavioral Effects of an Enhanced Enrichment Program for Group-Housed Sooty Mangabeys (Cercocebus atys)

PubMed Central

Crast, Jessica; Bloomsmith, Mollie A; Jonesteller, Trina J

2016-01-01

Evaluating the behavioral effects of enrichment on animals housed in biomedical facilities is necessary to effectively support their care and wellbeing. We tested the cumulative effects of an enhanced enrichment program on sooty mangabey behavior: locomotion, feeding and foraging, manipulating items in the enclosure, social affiliation, aggression, and abnormal behavior. The enhanced enrichment program included the addition of a substrate (timothy hay), widely distributing small pieces of produce and a forage mixture in the hay, adding structures and perching, and increasing the variety of food items, foraging devices, and other manipulable items. We tested 10 groups living in runs (n = 54) by using an ABA experimental design (phase A, standard enrichment; phase B, enhanced enrichment) and Wilcoxon signed-rank tests to compare behavior across phases. During phase B, subjects significantly increased feeding, foraging, and manipulation of items, and they decreased self-grooming, social affiliation, and aggression. Combined enrichment use increased from approximately 10% to 21% of the mangabeys’ time. Enhanced enrichment did not affect locomotion or abnormal behavior. The increases in feeding, foraging, and manipulation during enhanced enrichment were driven primarily by the subjects’ preference for foraging in the hay: it was the most effective component of the program in promoting feeding and foraging behavior, which comprises the majority of wild sooty mangabeys’ daily activity. Developing an effective, species-appropriate, and comprehensive enrichment program is essential to successfully promote the health and wellbeing of captive NHP. PMID:27931313

Behavioral Effects of an Enhanced Enrichment Program for Group-Housed Sooty Mangabeys (Cercocebus atys).

PubMed

Crast, Jessica; Bloomsmith, Mollie A; Jonesteller, Trina J

2016-11-01

Evaluating the behavioral effects of enrichment on animals housed in biomedical facilities is necessary to effectively support their care and wellbeing. We tested the cumulative effects of an enhanced enrichment program on sooty mangabey behavior: locomotion, feeding and foraging, manipulating items in the enclosure, social affiliation, aggression, and abnormal behavior. The enhanced enrichment program included the addition of a substrate (timothy hay), widely distributing small pieces of produce and a forage mixture in the hay, adding structures and perching, and increasing the variety of food items, foraging devices, and other manipulable items. We tested 10 groups living in runs (n = 54) by using an ABA experimental design (phase A, standard enrichment; phase B, enhanced enrichment) and Wilcoxon signed-rank tests to compare behavior across phases. During phase B, subjects significantly increased feeding, foraging, and manipulation of items, and they decreased self-grooming, social affiliation, and aggression. Combined enrichment use increased from approximately 10% to 21% of the mangabeys' time. Enhanced enrichment did not affect locomotion or abnormal behavior. The increases in feeding, foraging, and manipulation during enhanced enrichment were driven primarily by the subjects' preference for foraging in the hay: it was the most effective component of the program in promoting feeding and foraging behavior, which comprises the majority of wild sooty mangabeys' daily activity. Developing an effective, species-appropriate, and comprehensive enrichment program is essential to successfully promote the health and wellbeing of captive NHP.

75 FR 9380 - Cooperative Conservation Partners Initiative; Wetlands Reserve Enhancement Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-02

... Corporation Cooperative Conservation Partners Initiative; Wetlands Reserve Enhancement Program AGENCY...: Notice of request for proposals through the Mississippi River Basin Healthy Watersheds Initiative... (FY) 2010 for up to $50 million in the Cooperative Conservation Partnership Initiative (CCPI) and $25...

50 CFR 84.20 - What are the grant eligibility requirements?

Code of Federal Regulations, 2011 CFR

2011-10-01

... restoration, enhancement, or management of coastal wetlands ecosystems, providing restoration, enhancement, or... THE INTERIOR (CONTINUED) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM NATIONAL COASTAL WETLANDS CONSERVATION GRANT PROGRAM Applying for Grants § 84.20 What are the grant eligibility requirements...

Community-based participatory research to design a faith-enhanced diabetes prevention program: The Better Me Within randomized trial.

PubMed

Kitzman, Heather; Dodgen, Leilani; Mamun, Abdullah; Slater, J Lee; King, George; Slater, Donna; King, Alene; Mandapati, Surendra; DeHaven, Mark

2017-11-01

Reducing obesity positively impacts diabetes and cardiovascular risk; however, evidence-based lifestyle programs, such as the diabetes prevention program (DPP), show reduced effectiveness in African American (AA) women. In addition to an attenuated response to lifestyle programs, AA women also demonstrate high rates of obesity, diabetes, and cardiovascular disease. To address these disparities, enhancements to evidence-based lifestyle programs for AA women need to be developed and evaluated with culturally relevant and rigorous study designs. This study describes a community-based participatory research (CBPR) approach to design a novel faith-enhancement to the DPP for AA women. A long-standing CBPR partnership designed the faith-enhancement from focus group data (N=64 AA adults) integrating five components: a brief pastor led sermon, memory verse, in class or take-home faith activity, promises to remember, and scripture and prayer integrated into participant curriculum and facilitator materials. The faith components were specifically linked to weekly DPP learning objectives to strategically emphasize behavioral skills with religious principles. Using a CBPR approach, the Better Me Within trial was able to enroll 12 churches, screen 333 AA women, and randomize 221 (M age =48.8±11.2; M BMI =36.7±8.4; 52% technical or high school) after collection of objective eligibility measures. A prospective, randomized, nested by church, design will be used to evaluate the faith-enhanced DPP as compared to a standard DPP on weight, diabetes and cardiovascular risk, over a 16-week intervention and 10-month follow up. This study will provide essential data to guide enhancements to evidence-based lifestyle programs for AA women who are at high risk for chronic disease. Copyright © 2017 Elsevier Inc. All rights reserved.

Enhancing fire department home visiting programs: results of a community intervention trial.

PubMed

Gielen, Andrea C; Shields, Wendy; Frattaroli, Shannon; McDonald, Eileen; Jones, Vanya; Bishai, David; O'Brocki, Raymond; Perry, Elise C; Bates-Hopkins, Barbara; Tracey, Pat; Parsons, Stephanie

2013-01-01

This study evaluates the impact of an enhanced fire department home visiting program on community participation and installation of smoke alarms, and describes the rate of fire and burn hazards observed in homes. Communities were randomly assigned to receive either a standard or enhanced home visiting program. Before implementing the program, 603 household surveys were completed to determine comparability between the communities. During a 1-year intervention period, 171 home visits took place with 8080 homes. At baseline, 60% of homes did not have working smoke alarms on every level, 44% had unsafe water temperatures, and 72% did not have carbon monoxide alarms. Residents in the enhanced community relative to those in the standard community were significantly more likely to let the fire fighters into their homes (75 vs 62%). Among entered homes, those in the enhanced community were significantly more likely to agree to have smoke alarms installed (95 vs 92%), to be left with a working smoke alarm on every level of the home (84 vs 78%), and to have more smoke alarms installed per home visited (1.89 vs 1.74). The high baseline rates of home hazards suggest that fire department home visiting programs should take an "all hazards" approach. Community health workers and community partnerships can be effective in promoting fire departments' fire and life safety goals. Public health academic centers should partner with the fire service to help generate evidence on program effectiveness that can inform decision making about resource allocation for prevention.

Operator performance-enhancing technologies to improve safety. A US DOT safety initiative for meeting the human-centered systems challenge.

DOT National Transportation Integrated Search

1999-11-01

The program implements DOT Human Factors Coordinating Committee (HFCC) recommendations for a coordinated Departmental Human Factors Research Program to advance the human-centered systems approach for enhancing transportation safety. Human error is a ...

76 FR 23971 - Proposed Information Collection; Comment Request; Competitive Enhancement Needs Assessment Survey...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-29

... DEPARTMENT OF COMMERCE Bureau of Industry and Security Proposed Information Collection; Comment Request; Competitive Enhancement Needs Assessment Survey Program AGENCY: Bureau of Industry and Security... their abilities to meet defense program needs. The information collected from voluntary surveys will be...

A Decision Support Framework for Feasibility Analysis of International Space Station (ISS) Research Capability Enhancing Options

NASA Technical Reports Server (NTRS)

Ortiz, James N.; Scott,Kelly; Smith, Harold

2004-01-01

The assembly and operation of the ISS has generated significant challenges that have ultimately impacted resources available to the program's primary mission: research. To address this, program personnel routinely perform trade-off studies on alternative options to enhance research. The approach, content level of analysis and resulting outputs of these studies vary due to many factors, however, complicating the Program Manager's job of selecting the best option. To address this, the program requested a framework be developed to evaluate multiple research-enhancing options in a thorough, disciplined and repeatable manner, and to identify the best option on the basis of cost, benefit and risk. The resulting framework consisted of a systematic methodology and a decision-support toolset. The framework provides quantifiable and repeatable means for ranking research-enhancing options for the complex and multiple-constraint domain of the space research laboratory. This paper describes the development, verification and validation of this framework and provides observations on its operational use.

Participation in Older Adult Physical Activity Programs and Risk for Falls Requiring Medical Care, Washington State, 2005-2011.

PubMed

Greenwood-Hickman, Mikael Anne; Rosenberg, Dori E; Phelan, Elizabeth A; Fitzpatrick, Annette L

2015-06-11

Physical activity is known to prevent falls; however, use of widely available exercise programs for older adults, including EnhanceFitness and Silver Sneakers, has not been examined in relation to effects on falls among program participants. We aimed to determine whether participation in EnhanceFitness or Silver Sneakers is associated with a reduced risk of falls resulting in medical care. A retrospective cohort study examined a demographically representative sample from a Washington State integrated health system. Health plan members aged 65 or older, including 2,095 EnhanceFitness users, 13,576 Silver Sneakers users, and 55,127 nonusers from 2005 through 2011, were classified as consistent users (used a program ≥2 times in all years they were enrolled in the health plan during the study period); intermittent users (used a program ≥2 times in 1 or more years enrolled but not all years), or nonusers of EnhanceFitness or Silver Sneakers. The main outcome was measured as time-to-first-fall requiring inpatient or out-of-hospital medical treatment based on the International Classification of Diseases, 9th Revision, Clinical Modification, Sixth Edition and E-codes. In fully adjusted Cox proportional hazards models, consistent (hazard ratio [HR], 0.74; 95% confidence interval [CI], 0.63-0.88) and intermittent (HR, 0.87; 95% CI, 0.8-0.94) EnhanceFitness participation were both associated with a reduced risk of falls resulting in medical care. Intermittent Silver Sneakers participation showed a reduced risk (HR, 0.93; 95% CI, 0.90-0.97). Participation in widely available community-based exercise programs geared toward older adults (but not specific to fall prevention) reduced the risk of medical falls. Structured programs that include balance and strength exercise, as EnhanceFitness does, may be effective in reducing fall risk.

A Training Program to Enhance Postgraduate Students' Research Skills in Preparing a Research Proposal in the Field of Curriculum and Instruction Methods of Arabic Language

ERIC Educational Resources Information Center

Alfakih, Ahmed Hassan

2017-01-01

The study examined the impact of a training program on enhancing postgraduate students' research skills in preparing a research proposal. The nature of the skills required to prepare a research proposal were first determined using a questionnaire. A training program for improving such skills was then constructed and seven postgraduate students in…

Long-term usage of modern signal processing by listeners with severe or profound hearing loss: a retrospective survey.

PubMed

Keidser, Gitte; Hartley, David; Carter, Lyndal

2008-12-01

To investigate the long-term benefit of multichannel wide dynamic range compression (WDRC) alone and in combination with directional microphones and noise reduction/speech enhancement for listeners with severe or profound hearing loss. At the conclusion of a research project, 39 participants with severe or profound hearing loss were fitted with WDRC in one program and WDRC with directional microphones and speech enhancement enabled in a 2nd program. More than 2 years after the 1st participants exited the project, a retrospective survey was conducted to determine the participants' use of, and satisfaction with, the 2 programs. From the 30 returned questionnaires, it seems that WDRC is used with a high degree of satisfaction in general everyday listening situations. The reported benefit from the addition of a directional microphone and speech enhancement for listening in noisy environments was lower and varied among the users. This variable was significantly correlated with how much the program was used. The less frequent and more varied use of the program with directional microphones and speech enhancement activated in combination suggests that these features may be best offered in a 2nd listening program for listeners with severe or profound hearing loss.

Adapting a robotics program to enhance participation and interest in STEM among children with disabilities: a pilot study.

PubMed

Lindsay, Sally; Hounsell, Kara Grace

2017-10-01

Youth with disabilities are under-represented in science, technology, engineering, and math (STEM) in school and in the workforce. One encouraging approach to engage youth's interest in STEM is through robotics; however, such programs are mostly for typically developing youth. The purpose of this study was to understand the development and implementation of an adapted robotics program for children and youth with disabilities and their experiences within it. Our mixed methods pilot study (pre- and post-workshop surveys, observations, and interviews) involved 41 participants including: 18 youth (aged 6-13), 12 parents and 11 key informants. The robotics program involved 6, two-hour workshops held at a paediatric hospital. Our findings showed that several adaptations made to the robotics program helped to enhance the participation of children with disabilities. Adaptations addressed the educational/curriculum, cognitive and learning, physical and social needs of the children. In regards to experiences within the adapted hospital program, our findings highlight that children enjoyed the program and learned about computer programming and building robots. Clinicians and educators should consider engaging youth with disabilities in robotics to enhance learning and interest in STEM. Implications for Rehabilitation Clinicians and educators should consider adapting curriculum content and mode of delivery of LEGO ® robotics programs to include youth with disabilities. Appropriate staffing including clinicians and educators who are knowledgeable about youth with disabilities and LEGO ® robotics are needed. Clinicians should consider engaging youth with disabilities in LEGO ® to enhance learning and interest in STEM.

Data analysis software for the autoradiographic enhancement process. Volumes 1, 2, and 3, and appendix

NASA Technical Reports Server (NTRS)

Singh, S. P.

1979-01-01

The computer software developed to set up a method for Wiener spectrum analysis of photographic films is presented. This method is used for the quantitative analysis of the autoradiographic enhancement process. The software requirements and design for the autoradiographic enhancement process are given along with the program listings and the users manual. A software description and program listings modification of the data analysis software are included.

Montana Health Enhancement...An Expanded Concept: Assessment and Planning.

ERIC Educational Resources Information Center

Montana State Dept. of Public Instruction, Helena.

Comprehensive health enhancement programs (CHEPs) are a curricular area required by new Montana accreditation standards. The curriculum combines the disciplines of health and physical education into an integrated, holistic, health-oriented program. A CHEP incorporates an expanded concept of health services--healthy school environment, employee…

A Sexual Enhancement Program for Elderly Couples

ERIC Educational Resources Information Center

Rowland, Kay F.; Haynes, Stephen N.

1978-01-01

This study examined effects of a group sexual enhancement program for elderly couples. The three two-week phases, pretreatment with no therapist contact, education on human sexual functioning in aging people, and communication exercises-sexual techniques, were methods to improve communication and increase enjoyment of sexual contact. (Author)

Relapse Prevention in Health Promotion: Strategies and Long-Term Outcome.

ERIC Educational Resources Information Center

Gintner, Gary G.

1988-01-01

Reviews the efficacy of maintenance enhancement procedures to prevent relapse in smoking cessation, weight control, and exercise programs. Presents models of maintenance enhancement, reviews studies that have used relapse prevention strategies, and discusses ways of incorporating relapse prevention techniques into health promotion programs.…

76 FR 65107 - Recovery of Delinquent Debts-Treasury Offset Program Enhancements

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-20

... SOCIAL SECURITY ADMINISTRATION 20 CFR Parts 404, 408, 416, and 422 [Docket No. SSA-2010-0010] RIN 0960-AH19 Recovery of Delinquent Debts--Treasury Offset Program Enhancements AGENCY: Social Security... Recovery Policy, Social Security Administration, 6401 Security Boulevard, Baltimore, MD 21235-6401, (410...

Let's get technical: Enhancing program evaluation through the use and integration of internet and mobile technologies.

PubMed

Materia, Frank T; Miller, Elizabeth A; Runion, Megan C; Chesnut, Ryan P; Irvin, Jamie B; Richardson, Cameron B; Perkins, Daniel F

2016-06-01

Program evaluation has become increasingly important, and information on program performance often drives funding decisions. Technology use and integration can help ease the burdens associated with program evaluation by reducing the resources needed (e.g., time, money, staff) and increasing evaluation efficiency. This paper reviews how program evaluators, across disciplines, can apply internet and mobile technologies to key aspects of program evaluation, which consist of participant registration, participant tracking and retention, process evaluation (e.g., fidelity, assignment completion), and outcome evaluation (e.g., behavior change, knowledge gain). In addition, the paper focuses on the ease of use, relative cost, and fit with populations. An examination on how these tools can be integrated to enhance data collection and program evaluation is discussed. Important limitations of and considerations for technology integration, including the level of technical skill, cost needed to integrate various technologies, data management strategies, and ethical considerations, are highlighted. Lastly, a case study of technology use in an evaluation conducted by the Clearinghouse for Military Family Readiness at Penn State is presented and illustrates how technology integration can enhance program evaluation. Copyright © 2016 Elsevier Ltd. All rights reserved.

The Mount Sinai international enhancement of social work leadership program: The past and the future.

PubMed

Gordon, Elisa; Green, Karen; Whitwam, Louisa; Epstein, Irwin; Bernstein, Susan

2018-07-01

Developed in 1988, the Mount Sinai International Enhancement of Social Work Leadership Program brings 4-6 social workers from several countries each year to the Mount Sinai Hospital in New York City, where they meet with leaders from the hospital, community based organizations and graduate schools of social work, to enhance their leadership ability, strengthen management and research skills, and build upon global social work relationships. This article reviews the results of a survey conducted in 2016 to assess whether the visiting scholars met established learning objectives of the Program. Survey outcomes, presented in quantitative and qualitative terms, show positive results, and the scholars reported that the Program was extremely beneficial. The Program is viewed through the lens of two select adult learning theories: Social Learning Theory, which incorporates collaboration and learning from others, and Transformative Learning Theory, which is comprised of self-reflection and individualized learning. The inclusion of these theories in the implementation of the Program will be discussed. An analysis of the survey's outcomes, through pre- and post-Program participation and learning, facilitates assessment of potential programmatic adjustments to help evaluate long-term viability of the Program and potential duplication by other academic medical centers.

Empirical application of empathy enhancing program based on movement concept for married couples in conflict

PubMed Central

Kim, Soo-Yeon; Kang, Hye-Won; Chung, Yong-Chul; Park, Seungha

2013-01-01

In the field of marital therapy, it is known that couple movement program helps married couples faced with conflict situation to rebuild the relationship and to maintain a family homeostasis. The purpose of this study was to configure and apply the kinesthetic empathy program and to assess the effectiveness for married couples in conflict. To achieve the research aims, qualitative research method has been conducted, subjecting three couples, 6 people, who are participating in expressive movement program for this study. The study used focus group interview method for collecting date and employed for the interview method by mixing the semi-structured and unstructured questionnaire. The results were followings. First, through kinesthetic empathy enhancing program, one could develop self-awareness and emotional attunement. Second, the result showed the relationship between intention and empathy. It shows that “knowing spouse’s hidden intention” is significant factors to understand others. Third, kinesthetic empathy program could complement general marriage counseling program. The results of this study provide empirical evidence that movement program functions as an empathy enhancer through the process of perceiving, feeling, thinking, and interacting with others. PMID:24278896

International comparison and review of a health technology assessment skills program.

PubMed

Wanke, Margaret I; Juzwishin, Don

2005-01-01

A review of the Alberta Heritage Foundation for Medical Research's (AHFMR) 6-month Health Technology Skills Development Program was undertaken within an international context with the purpose of describing and assessing the current program, further formalizing the program based on identified opportunities for improvement, and enhancing collaborative linkages with other agencies. The objectives of the review were to (i) compare the AHFMR program with similar programs in other health technology assessment (HTA) agencies internationally; (ii) assess the value of the program; (iii) identify program strengths and opportunities for improvement; and (iv) review, critique, and recommend enhancements to the program model and role description. The review involved a qualitative study design that included a survey of the Skills Development Program participants' experience and perceptions; semistructured interviews with program stakeholders, and a written survey of HTA agencies/programs in other Canadian and international jurisdictions. The review concluded that the program was successful and valued by participants, the Foundation, and stakeholders in the policy and research communities. Findings suggest participant products have a potential for broad influence, including impact on funding decisions related to technology diffusion, influence through publications and presentations, and knowledge transfer in the participants' disciplines and employment settings. The main opportunity for enhancement was to differentiate the program into two streams according to different needs of participants, specifically between those who desire to be HTA producers and/or make HTA their careers, and those who desire to apply HTA in their employment capacity as policy or clinical decision-makers.

Enhanced surveillance program FY97 accomplishments. Progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mauzy, A.; Laake, B.

1997-10-01

This annual report is one volume of the Enhanced Surveillance Program (ESP) FY97 Accomplishments. The complete accomplishments report consists of 11 volumes. Volume 1 includes an ESP overview and a summary of selected unclassified FY97 program highlights. Volume 1 specifically targets a general audience, reflecting about half of the tasks conducted in FY97 and emphasizing key program accomplishments and contributions. The remaining volumes of the accomplishments report are classified, organized by program focus area, and present in technical detail the progress achieved in each of the 104 FY97 program tasks. Focus areas are as follows: pits; high explosives; organics; dynamics;more » diagnostics; systems; secondaries; nonnuclear materials; nonnuclear components; and Surveillance Test Program upgrades.« less

A novel LSD1 inhibitor NCD38 ameliorates MDS-related leukemia with complex karyotype by attenuating leukemia programs via activating super-enhancers.

PubMed

Sugino, N; Kawahara, M; Tatsumi, G; Kanai, A; Matsui, H; Yamamoto, R; Nagai, Y; Fujii, S; Shimazu, Y; Hishizawa, M; Inaba, T; Andoh, A; Suzuki, T; Takaori-Kondo, A

2017-11-01

Lysine-specific demethylase 1 (LSD1) regulates gene expression by affecting histone modifications and is a promising target for acute myeloid leukemia (AML) with specific genetic abnormalities. Novel LSD1 inhibitors, NCD25 and NCD38, inhibited growth of MLL-AF9 leukemia as well as erythroleukemia, megakaryoblastic leukemia and myelodysplastic syndromes (MDSs) overt leukemia cells in the concentration range that normal hematopoiesis was spared. NCD25 and NCD38 invoked the myeloid development programs, hindered the MDS and AML oncogenic programs, and commonly upregulated 62 genes in several leukemia cells. NCD38 elevated H3K27ac level on enhancers of these LSD1 signature genes and newly activated ~500 super-enhancers. Upregulated genes with super-enhancer activation in erythroleukemia cells were enriched in leukocyte differentiation. Eleven genes including GFI1 and ERG, but not CEBPA, were identified as the LSD1 signature with super-enhancer activation. Super-enhancers of these genes were activated prior to induction of the transcripts and myeloid differentiation. Depletion of GFI1 attenuated myeloid differentiation by NCD38. Finally, a single administration of NCD38 causes the in vivo eradication of primary MDS-related leukemia cells with a complex karyotype. Together, NCD38 derepresses super-enhancers of hematopoietic regulators that are silenced abnormally by LSD1, attenuates leukemogenic programs and consequently exerts anti-leukemic effect against MDS-related leukemia with adverse outcome.

High enantioselective Novozym 435-catalyzed esterification of (R,S)-flurbiprofen monitored with a chiral stationary phase.

PubMed

Siódmiak, Tomasz; Mangelings, Debby; Vander Heyden, Yvan; Ziegler-Borowska, Marta; Marszałł, Michał Piotr

2015-03-01

Lipases form Candida rugosa and Candida antarctica were tested for their application in the enzymatic kinetic resolution of (R,S)-flurbiprofen by enantioselective esterification. Successful chromatographic separation with well-resolved peaks of (R)- and (S)-flurbiprofen and their esters was achieved in one run on chiral stationary phases by high-performance liquid chromatography (HPLC). In this study screening of enzymes was performed, and Novozym 435 was selected as an optimal catalyst for obtaining products with high enantiopurity. Additionally, the influence of organic solvents (dichloromethane, dichloroethane, dichloropropane, and methyl tert-butyl ether), primary alcohols (methanol, ethanol, n-propanol, and n-butanol), reaction time, and temperature on the enantiomeric ratio and conversion was tested. The high values of enantiomeric ratio (E in the range of 51.3-90.5) of the esterification of (R,S)-flurbiprofen were obtained for all tested alcohols using Novozym 435, which have a great significance in the field of biotechnological synthesis of drugs. The optimal temperature range for the performed reactions was from 37 to 45 °C. As a result of the optimization, (R)-flurbiprofen methyl ester was obtained with a high optical purity, eep = 96.3 %, after 96 h of incubation. The enantiomeric ratio of the reaction was E = 90.5 and conversion was C = 35.7 %.

Additional development of the XTRAN3S computer program

NASA Technical Reports Server (NTRS)

Borland, C. J.

1989-01-01

Additional developments and enhancements to the XTRAN3S computer program, a code for calculation of steady and unsteady aerodynamics, and associated aeroelastic solutions, for 3-D wings in the transonic flow regime are described. Algorithm improvements for the XTRAN3S program were provided including an implicit finite difference scheme to enhance the allowable time step and vectorization for improved computational efficiency. The code was modified to treat configurations with a fuselage, multiple stores/nacelles/pylons, and winglets. Computer program changes (updates) for error corrections and updates for version control are provided.

Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex

PubMed Central

Liu, Zhijie; Merkurjev, Daria; Yang, Feng; Li, Wenbo; Oh, Soohwan; Friedman, Meyer J.; Song, Xiaoyuan; Zhang, Feng; Ma, Qi; Ohgi, Kenneth; Krones, Anna; Rosenfeld, Michael G.

2014-01-01

Summary Enhancers provide critical information directing cell-type specific transcriptional programs, regulated by binding of signal-dependent transcription factors and their associated cofactors. Here we report that the most strongly activated estrogen (E2)-responsive enhancers are characterized by trans-recruitment and in situ assembly of a large 1-2 MDa complex of diverse DNA-binding transcription factors by ERα at ERE-containing enhancers. We refer to enhancers recruiting these factors as mega transcription factor-bound in trans (MegaTrans) enhancers. The MegaTrans complex is a signature of the most potent functional enhancers and is required for activation of enhancer RNA transcription and recruitment of coactivators, including p300 and Med1. The MegaTrans complex functions, in part, by recruiting specific enzymatic machinery, exemplified by DNA-dependent protein kinase. Thus, MegaTrans-containing enhancers represent a cohort of functional enhancers that mediate a broad and important transcriptional program and provide a molecular explanation for transcription factor clustering and hotspots noted in the genome. PMID:25303530

Effect of Subliminal Stimulation of Symbiotic Fantasies on Behavior Modification Treatment of Obesity.

ERIC Educational Resources Information Center

And Others; Silverman, Lloyd H.

1978-01-01

Obese women were treated in behavior modification programs for overeating. Behavior programs were accompanied by subliminal stimulation and by symbiotic and control messages. The symbiotic condition gave evidence of enhancing weight loss. This finding supports the proposition that subliminal stimulation of symbiotic fantasies can enhance the…

Facilitating Facilitators: Enhancing PBL through a Structured Facilitator Development Program

ERIC Educational Resources Information Center

Salinitri, Francine D.; Wilhelm, Sheila M.; Crabtree, Brian L.

2015-01-01

With increasing adoption of the problem-based learning (PBL) model, creative approaches to enhancing facilitator training and optimizing resources to maintain effective learning in small groups is essential. We describe a theoretical framework for the development of a PBL facilitator training program that uses the constructivist approach as the…

Self-Concept Enhancement of Preschool Children.

ERIC Educational Resources Information Center

Landry, Richard G.; Pardew, E. Michelle

This study investigated whether a self-concept enhancement program would effect significant change in the self-concepts of 4-year-old middle class preschoolers as compared with classmates not in the program. All participating children (N=52) were pre- and posttested using the Thomas Self-Concept Values Test and the Developmental Profile. The…

NATIONAL STORMWATER CALCULATOR: LOW IMPACT DEVELOPMENT STORMWATER CONTROL COST ESTIMATION PROGRAMMING & FUTURE ENHANCEMENTS

EPA Science Inventory

National Stormwater Calculator: Low Impact Development Stormwater Control Cost Estimation Programming & Future EnhancementsJason Berner1; Michael Tryby1; Scott Struck2, Dan Pankani2, Marion Deerhake3, Michelle Simon11. USEPA2. GeoSyntec, Inc.3. RTI, Inc.The National Stormwater Ca...

15 CFR 923.121 - General.

Code of Federal Regulations, 2010 CFR

2010-01-01

... ZONE MANAGEMENT PROGRAM REGULATIONS Coastal Zone Enhancement Grants Program § 923.121 General. (a) The purpose of this subpart is to set forth the criteria and procedures for awarding coastal zone enhancement grants under section 309 of the Coastal Zone Management Act, as amended (16 U.S.C. 1456). This subpart...

15 CFR 923.126 - Pre-application procedures.

Code of Federal Regulations, 2011 CFR

2011-01-01

... MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Coastal Zone Enhancement Grants Program § 923.126 Pre... one or more of the coastal zone enhancement objectives. (8) If the sum of estimated project costs for...) The Assistant Administrator may seek advice from technical experts in the fields of the coastal zone...

15 CFR 923.121 - General.

Code of Federal Regulations, 2011 CFR

2011-01-01

... ZONE MANAGEMENT PROGRAM REGULATIONS Coastal Zone Enhancement Grants Program § 923.121 General. (a) The purpose of this subpart is to set forth the criteria and procedures for awarding coastal zone enhancement grants under section 309 of the Coastal Zone Management Act, as amended (16 U.S.C. 1456). This subpart...

Training in Rational-Behavior Problem Solving and Employability Enhancement of Rehabilitation Clients.

ERIC Educational Resources Information Center

Farley, Roy C.

1984-01-01

Examined the effects of a psychoeducational program on employability enhancement of 23 rehabilitation clients. The program had a significant, positive impact on clients' thinking, feeling, acting, and vocational outcome and reduced task-interfering beliefs, thoughts, emotions, and problem behavior. Participants had a lower vocational training…

Foreign Language/Area Studies Enhancement Project. Final Report.

ERIC Educational Resources Information Center

Felker, William; Fuller, Clark

The Foreign Language/Area Studies Enhancement Program at Central State University (Ohio) is an experience-centered work and study program in Africa designed to give students training in language, culture, and technology. It parallels and supports the university's northern Senegal water management project designed to promote self-sufficiency among…

Career Enhancement Program for the Industries of the Shenandoah Valley of Virginia. Performance Report.

ERIC Educational Resources Information Center

Merlin, Shirley B.

This document contains the performance report, external evaluation, and curricula for the Career Enhancement Program, a workplace literacy partnership conducted by James Madison University and Massanutten Technical Center for five companies in Virginia. The performance report describes how the project delivered individualized workplace literacy…

Enhancing the Knowledge Base in Educational Administration. UCEA Monograph Series.

ERIC Educational Resources Information Center

Wendel, Frederick C., Ed.

Effective administrator preparation programs and professional practices are important to enhancing principals' knowledge base. In chapter 1 of this report, "Strategies of Organizing Principal Preparation: A Survey of the Danforth Principal Preparation Program," Gerald C. Ubben and Frances C. Fowler discuss their survey of facilitators of the…

Enhancing the Quality of Tutorials through Peer-Connected Tutor Training

ERIC Educational Resources Information Center

Calma, Angelito; Eggins, Mark

2012-01-01

This paper investigates how a peer-connected tutor training program can lead to quality enhancement by helping tutors to develop more effective teaching strategies and promoting better learning approaches among business students. It uses 2007-2010 evaluation data from 343 program participants from accounting, economics, finance and management and…

Development of Program to Enhance Strategic Leadership of Secondary School Administrators

ERIC Educational Resources Information Center

Chatchawaphun, Pimpisa; Julsuwan, Suwat; Srisa-ard, Boonchom

2016-01-01

This research aimed to 1) study principles, attributes and skills needed for secondary school administrators, 2) investigate current situations, desirable conditions and needs for strategic secondary school administrators, 3) develop a strategic secondary school administrator enhancement program, and 4) explore the efficiency level of the…

Breast cancer survivorship program: testing for cross-cultural relevance.

PubMed

Chung, Lynna K; Cimprich, Bernadine; Janz, Nancy K; Mills-Wisneski, Sharon M

2009-01-01

Taking CHARGE, a theory-based self-management program, was developed to assist women with survivorship concerns that arise after breast cancer treatment. Few such programs have been evaluated for cultural relevance with diverse groups. This study determined the utility and cultural relevance of the program for African American (AA) breast cancer survivors. Two focus groups were held with AA women (n = 13), aged 41 to 72 years, who had completed primary treatment. Focus group participants assessed the program content, format, materials, and the self-regulation process. Content analysis of audiotapes was conducted using an open, focused coding process to identify emergent themes regarding program relevance and topics requiring enhancement and/or further emphasis. Although findings indicated that the program's content was relevant to participants' experiences, AA women identified need for cultural enhancements in spirituality, self-preservation, and positive valuations of body image. Content areas requiring more emphasis included persistent fatigue, competing demands, disclosure, anticipatory guidance, and age-specific concerns about body image/sexuality. Suggested improvements to program materials included portable observation logs, additional resources, more photographs of younger AA women, vivid colors, and images depicting strength. These findings provide the basis for program enhancements to increase the utility and cultural relevance of Taking CHARGE for AA survivors and underscore the importance of evaluating interventions for racially/ethnically diverse groups.

Enhancing Fire Department Home Visiting Programs: Results of a Community Intervention Trial

PubMed Central

Gielen, Andrea C.; Shields, Wendy; Frattaroli, Shannon; McDonald, Eileen; Jones, Vanya; Bishai, David; O’Brocki, Raymond; Perry, Elise C.; Bates-Hopkins, Barbara; Tracey, Pat; Parsons, Stephanie

2012-01-01

Background This study evaluates the impact of an enhanced fire department home visiting program on community participation and installation of smoke alarms and describes the rate of fire and burn hazards observed in homes. Methods Communities were randomly assigned to receive either a standard or enhanced home visiting program. Prior to implementing the program, 603 household surveys were completed to determine comparability between the communities. During a one year intervention period, 171 home visit events took place with 8,080 homes. Results At baseline, 60% of homes did not have working smoke alarms on every level; 44% had unsafe water temperatures; and 72% did not have CO alarms. Residents in the enhanced community relative to those in the standard community were significantly more likely to let the fire fighters into their homes (75% vs 62%). Among entered homes, those in the enhanced community were significantly more likely to agree to have smoke alarms installed (95% vs 92%), to be left with a working smoke alarm on every level of the home (84% vs 78%) and to have more smoke alarms installed per home visited (1.89 vs 1.74). Conclusions The high baseline rates of home hazards suggest that fire department home visiting programs should take an “all hazards” approach. CHWs and other community partnerships can be effective in promoting fire departments’ fire and life safety goals. Public health academic centers should partner with the fire service to help generate evidence on program effectiveness that can inform decision making about resource allocation for prevention. PMID:23237821

From empower to Green Dot : successful strategies and lessons learned in developing comprehensive sexual violence primary prevention programming.

PubMed

Cook-Craig, Patricia G; Millspaugh, Phyllis H; Recktenwald, Eileen A; Kelly, Natalie C; Hegge, Lea M; Coker, Ann L; Pletcher, Tisha S

2014-10-01

This case study describes Kentucky's partnership with the Centers for Disease Control and Prevention (CDC) EMPOWER (Enhancing and Making Programs Work to End Rape) program to enhance the mission and services of existing rape crisis centers to include comprehensive primary prevention programming to reduce rates of sexual violence perpetration. The planning process and the successful implementation of a statewide, 5-year, randomized control trial study of a bystander prevention program (Green Dot), and its evaluation are described. Lessons learned in generating new questions, seeking funding, building relationships and capacity, and disseminating knowledge are presented. © The Author(s) 2014.

Request Twin Screw Extruder to Enhance DoD Interested Polymer Nanocomposite Research and STEM Program

DTIC Science & Technology

2016-09-25

can meet specific requirements for a wide range of polymers and composites. Particularly, because of the similarity between twin screw extruder and...Release; Distribution Unlimited UU UU UU UU 25-09-2016 1-Feb-2015 30-Apr-2016 Request Twin Screw Extruder to Enhance DoD Interested Polymer ...Request Twin Screw Extruder to Enhance DoD Interested Polymer Nanocomposite Research and STEM Program Report Title In comparison to our existing melt

Annual Technical Symposium (28th): Achieving Technical and Management Excellence. Held in Arlington, Virginia on April 11, 1991,

DTIC Science & Technology

1991-04-11

Perplexed: Think Energy Again. Video Enhanced SECAT - An Energy Program; Quality Ship Service Power with an Integrated Diesel Electric Propulsion...DIesign Branch (5011), NAVSEA * "Think Energy Again! Video Enhanced SECAT - 5 An Energy Program"’ Hasan Pehlivan, Mechanical Engineer/Ship Trials, Surface...1.015, or 1.5% increase.) Association of Scientists and Engineers 28th Annual Technical Symposium, 11 April 1991 THINK ENERGY AGAIN! A VIDEO ENHANCED

Enhancement of Antiviral Agents Through the Use of Controlled-Release Technology.

DTIC Science & Technology

DL-lactide-co-glycolide) to be used as the polymeric excipients in the microencapsulation work. In addition, we have actively pursued development and testing of poly(I.C) and Je vaccine microcapsule formulations....of this research program are a) To develop a programmed-release delivery system ( microcapsule system) designed to enhance the immunogenic potential of...release microcapsule delivery systems that will enhance the effects of the following immune modulators and antiviral agents: muramyl tripeptide (MTP

Enhanced TCAS 2/CDTI traffic Sensor digital simulation model and program description

NASA Technical Reports Server (NTRS)

Goka, T.

1984-01-01

Digital simulation models of enhanced TCAS 2/CDTI traffic sensors are developed, based on actual or projected operational and performance characteristics. Two enhanced Traffic (or Threat) Alert and Collision Avoidance Systems are considered. A digital simulation program is developed in FORTRAN. The program contains an executive with a semireal time batch processing capability. The simulation program can be interfaced with other modules with a minimum requirement. Both the traffic sensor and CAS logic modules are validated by means of extensive simulation runs. Selected validation cases are discussed in detail, and capabilities and limitations of the actual and simulated systems are noted. The TCAS systems are not specifically intended for Cockpit Display of Traffic Information (CDTI) applications. These systems are sufficiently general to allow implementation of CDTI functions within the real systems' constraints.

Facilitating the exploitation of ERTS imagery using snow enhancement techniques. [geological mapping of New England test area

NASA Technical Reports Server (NTRS)

Wobber, F. J.; Martin, K. R. (Principal Investigator); Amato, R. V.; Leshendok, T.

1974-01-01

The author has identified the following significant results. The procedure for conducting a regional geological mapping program utilizing snow-enhanced ERTS-1 imagery has been summarized. While it is recognized that mapping procedures in geological programs will vary from area to area and from geologist to geologist, it is believed that the procedure tested in this project is applicable over a wide range of mapping programs. The procedure is designed to maximize the utility and value of ERTS-1 imagery and aerial photography within the initial phase of geological mapping programs. Sample products which represent interim steps in the mapping formula (e.g. the ERTS Fracture-Lineament Map) have been prepared. A full account of these procedures and products will be included within the Snow Enhancement Users Manual.

Enhanced Recovery Pathway in Microvascular Autologous Tissue-Based Breast Reconstruction: Should It Become the Standard of Care?

PubMed

Kaoutzanis, Christodoulos; Ganesh Kumar, Nishant; O'Neill, Dillon; Wormer, Blair; Winocour, Julian; Layliev, John; McEvoy, Matthew; King, Adam; Braun, Stephane A; Higdon, K Kye

2018-04-01

Enhanced recovery pathway programs have demonstrated improved perioperative care and shorter length of hospital stay in several surgical disciplines. The purpose of this study was to compare outcomes of patients undergoing autologous tissue-based breast reconstruction before and after the implementation of an enhanced recovery pathway program. The authors retrospectively reviewed consecutive patients who underwent autologous tissue-based breast reconstruction performed by two surgeons before and after the implementation of the enhanced recovery pathway at a university center over a 3-year period. Patient demographics, perioperative data, and 45-day postoperative outcomes were compared between the traditional standard of care (pre-enhanced recovery pathway) and enhanced recovery pathway patients. Multivariate logistic regression was performed to identify risk factors for length of hospital stay. Cost analysis was performed. Between April of 2014 and January of 2017, 100 consecutive women were identified, with 50 women in each group. Both groups had similar demographics, comorbidities, and reconstruction types. Postoperatively, the enhanced recovery pathway cohort used significantly less opiate and more acetaminophen compared with the traditional standard of care cohort. Median length of stay was shorter in the enhanced recovery pathway cohort, which resulted in an extrapolated $279,258 savings from freeing up inpatient beds and increase in overall contribution margins of $189,342. Participation in an enhanced recovery pathway program and lower total morphine-equivalent use were independent predictors for decreased length of hospital stay. Overall 45-day major complication rates, partial flap loss rates, emergency room visits, hospital readmissions, and unplanned reoperations were similar between the two groups. Enhanced recovery pathway program implementation should be considered as the standard approach for perioperative care in autologous tissue-based breast reconstruction because it does not affect morbidity and is associated with accelerated recovery with reduced postoperative opiate use and decreased length of hospital stay, leading to downstream health care cost savings. Therapeutic, III.

A guide to transportation enhancements

DOT National Transportation Integrated Search

2004-12-01

The Federal Transportation Enhancement Program offers extensive opportunities to take unique and creative actions to integrate transportation into our communities and the natural environment. Transportation enhancement activities can be stand-alone p...

International Education Programs: Access to the World and Its Languages

ERIC Educational Resources Information Center

Office of Postsecondary Education, US Department of Education, 2012

2012-01-01

The International Education Programs Service (IEPS) administers 14 education programs. These programs are complementary in nature and designed to benefit a variety of audiences through training programs, research, start-up or enhancement projects, and fellowships. This paper provides brief descriptions of these programs.

Differential Programming Needs of College Students Preferring Web-Based Versus In-Person Physical Activity Programs.

PubMed

Goldstein, Stephanie P; Forman, Evan M; Butryn, Meghan L; Herbert, James D

2017-09-21

College students report several barriers to exercise, highlighting a need for university-based programs that address these challenges. In contrast to in-person interventions, several web-based programs have been developed to enhance program engagement by increasing ease of access and lowering the necessary level of commitment to participate. Unfortunately, web-based programs continue to struggle with engagement and less-than-ideal outcomes. One explanation for this discrepancy is that different intervention modalities may attract students with distinctive activity patterns, motivators, barriers, and program needs. However, no studies have formally evaluated intervention modality preference (e.g., web-based or in-person) among college students. The current study sought to examine the relationship between intervention modality preference and physical activity programming needs. Undergraduate students (n = 157) enrolled in psychology courses at an urban university were asked to complete an online survey regarding current activity patterns and physical activity program preferences. Participants preferring web-based physical activity programs exercised less (p = .05), were less confident in their abilities to exercise (p = .01), were less likely to endorse the maintenance stage of change (p < .01) and perceived more barriers to exercising (p < .01) than those who preferred in-person programming. Findings suggest that students preferring web-based programming may require programs that enhance self-efficacy by fostering goal-setting and problem-solving skills. A user-centered design approach may enhance the engagement (and therefore effectiveness) of physical activity promotion programs for college students.

Use of Immersive Simulations to Enhance Graduate Student Learning: Implications for Educational Leadership Programs

ERIC Educational Resources Information Center

Voelkel, Robert H.; Johnson, Christie W.; Gilbert, Kristen A.

2016-01-01

The purpose of this article is to present how one university incorporates immersive simulations through platforms which employ avatars to enhance graduate student understanding and learning in educational leadership programs. While using simulations and immersive virtual environments continues to grow, the literature suggests limited evidence of…

Studying Students' Attitudes on Using Examples of Game Source Code for Learning Programming

ERIC Educational Resources Information Center

Theodoraki, Aristea; Xinogalos, Stelios

2014-01-01

Games for learning are currently used in several disciplines for motivating students and enhancing their learning experience. This new approach of technology-enhanced learning has attracted researchers' and instructors' attention in the area of programming that is one of the most cognitively demanding fields in Computer Science. Several…

Moving through Moodle: Using E-Technology to Enhance Social Work Field Education

ERIC Educational Resources Information Center

Hay, Kathryn; Dale, Michael

2014-01-01

At Massey University, New Zealand, the Moodle program was introduced as an institutional innovation to support and enhance teaching and learning. Within the social work field education program Moodle has been embraced as an opportunity to creatively advance current educational practices. The development of a meta-site for field education enables…

Enhancing Intercultural Understanding for Pre-Service Teachers through Developing and Sustaining Education Abroad Experiences

ERIC Educational Resources Information Center

Marcus, Alan S.; Moss, David M.

2015-01-01

This article discusses two education abroad programs that afford pre-service teachers with purposeful opportunities to enhance their intercultural competence through immersion in teaching internships in British schools. The programs, in London and Nottingham, provide pre-service teachers with direct experiences that engage them with diverse…

A Professional Learning Program for Enhancing the Competency of Students with Special Needs

ERIC Educational Resources Information Center

Kantavong, Pennee; Sivabaedya, Suwaree

2010-01-01

This study used a quasi-experimental research design to examine the impact of a professional learning program designed to enhance the competency of children with Autism, Attention Deficit Hyperactivity Disorder and Learning Disabilities and to develop knowledge, understanding and skills of teachers and parents in helping them. Data were collected…

A 2-Year Progress Report of the AACAP-Harvard Macy Teaching Scholars Program

ERIC Educational Resources Information Center

Hunt, Jeffrey; Stubbe, Dorothy E.; Hanson, Mark; Al-Mateen, Cheryl S.; Cuccio, Anne; Dingle, Arden D.; Glowinski, Anne; Guthrie, Elizabeth; Kelley, Kathy; Malloy, Erin M.; Mehlinger, Renee; O'Melia, Anne; Shatkin, Jess; Anders, Thomas F.

2008-01-01

Objective: The American Academy of Child and Adolescent Psychiatry (AACAP) has partnered with the Harvard Macy Program for Healthcare Educators so that selected child and adolescent psychiatry academic faculty might enhance their teaching expertise in order to possibly enhance recruitment of medical students into child and adolescent psychiatry.…

75 FR 38023 - Approval and Promulgation of Air Quality Implementation Plans; California; Motor Vehicle...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-01

... the enhanced program performance standard evaluations to address: (1) A different attainment year for... the enhanced program performance standard evaluations, we concluded that the 2009 I/M Revision met the... national ambient air quality standards (NAAQSs) or any other applicable requirement of the Act. In so doing...

Perspective Transformation through College Summer Service Immersion Programs: Is Learning Enhanced by Sustained Engagement?

ERIC Educational Resources Information Center

Hudson, Tara D.; Serra, Susan; Shappell, Andrea Smith; Gray-Girton, Angela; Brandenberger, Jay

2017-01-01

Summer offers the opportunity for sustained community engagement through immersions in summer service-learning programs. A group of 16 colleges and universities that sponsor domestic and international summer service initiatives have formed a Summer Service Collaborative (SSC) to enhance preparation, immersion, and follow-up in light of the unique…

Relationships among Learning Styles and Motivation with Computer-Aided Instruction in an Agronomy Course

ERIC Educational Resources Information Center

McAndrews, Gina M.; Mullen, Russell E.; Chadwick, Scott A.

2005-01-01

Multi-media learning tools were developed to enhance student learning for an introductory agronomy course at Iowa State University. During fall 2002, the new interactive computer program, called Computer Interactive Multimedia Program for Learning Enhancement (CIMPLE) was incorporated into the teaching, learning, and assessment processes of the…

Expressive Writing: Enhancing the Emotional Intelligence of Human Services Majors

ERIC Educational Resources Information Center

Castillo, Yuleinys; Fischer, Jerome M.

2017-01-01

The skills and tasks in the human services field are highly connected to emotional intelligence abilities. The purpose of the study was to investigate the effect of an expressive writing program involving human service students in an undergraduate rehabilitation services course. The program was developed to enhance their emotional intelligence.…

Enhancing Understanding of Teaching and the Profession through School Innovation Rounds

ERIC Educational Resources Information Center

Moran, Wendy

2014-01-01

Currently, Australian teacher education programs include professional experiences as a means of enhancing preservice teacher understanding about teaching and the profession. The challenge the programs face is the lack of places available in schools and, at times, the unpredictable quality of the placements as some teachers are time-poor, are not…

77 FR 41190 - Office of Clinical and Preventive Services Funding Opportunity: National HIV Program for Enhanced...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-12

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Indian Health Service Office of Clinical and Preventive Services Funding Opportunity: National HIV Program for Enhanced HIV/AIDS Screening and Engagement in Care... Announcement Number: HHS-2012-IHS-OCPS-HIV-0001. Catalog of Federal Domestic Assistance Number: 93.933. The...

Linear Multimedia Benefits To Enhance Students' Ability To Comprehend Complex Subjects.

ERIC Educational Resources Information Center

Handal, Gilbert A.; Leiner, Marie A.; Gonzalez, Carlos; Rogel, Erika

The main objective of this program was to produce animated educational material to stimulate students' interest and learning process related to the sciences and to measure their impact. The program material was designed to support middle school educators with an effective, accessible, and novel didactic tool produced specifically to enhance and…

A Program to Enhance the Effectiveness of Teaching Assistants.

ERIC Educational Resources Information Center

Cornell Univ., Ithaca, NY. Coll. of Engineering.

This manual is the final report on a two-year project to enhance the effectiveness of teaching assistants. It is designed as a workbook for persons conducting instructional programs for teaching assistants and is specific to teaching assistants in engineering and the natural sciences. The manual contains an introduction and six chapters. Chapter…

Space station ECLSS integration analysis: Simplified General Cluster Systems Model, ECLS System Assessment Program enhancements

NASA Technical Reports Server (NTRS)

Ferguson, R. E.

1985-01-01

The data base verification of the ECLS Systems Assessment Program (ESAP) was documented and changes made to enhance the flexibility of the water recovery subsystem simulations are given. All changes which were made to the data base values are described and the software enhancements performed. The refined model documented herein constitutes the submittal of the General Cluster Systems Model. A source listing of the current version of ESAP is provided in Appendix A.

PRACA Enhancement Pilot Study Report: Engineering for Complex Systems Program (formerly Design for Safety), DFS-IC-0006

NASA Technical Reports Server (NTRS)

Korsmeyer, David; Schreiner, John

2002-01-01

This technology evaluation report documents the findings and recommendations of the Engineering for Complex Systems Program (formerly Design for Safety) PRACA Enhancement Pilot Study of the Space Shuttle Program's (SSP's) Problem Reporting and Corrective Action (PRACA) System. A team at NASA Ames Research Center (ARC) performed this Study. This Study was initiated as a follow-on to the NASA chartered Shuttle Independent Assessment Team (SIAT) review (performed in the Fall of 1999) which identified deficiencies in the current PRACA implementation. The Pilot Study was launched with an initial qualitative assessment and technical review performed during January 2000 with the quantitative formal Study (the subject of this report) started in March 2000. The goal of the PRACA Enhancement Pilot Study is to evaluate and quantify the technical aspects of the SSP PRACA systems and recommend enhancements to address deficiencies and in preparation for future system upgrades.

Internal contamination of an irradiator discovered during security enhancement.

PubMed

Harvey, R P

2014-08-01

High-risk radioactive sources regulated under Increased Controls Regulations have been protected by licensed facilities, but the federal government has placed significant emphasis on these sources and has developed initiatives to assist radioactive material licensees. The Department of Energy's Global Threat Reduction Initiative (GTRI) Domestic Threat Reduction Program is a voluntary federally funded program for security enhancements of high-risk radiological material. During the hardening or security enhancement process by the United States Department of Energy (U.S. DOE) contractors, a small amount of radioactive contamination was discovered in a Cesium irradiator. Ultimately, it was decided to pursue disposal with U.S. DOE's Off-Site Recovery Program (OSRP). Radiological devices may have a leaking source or known internal contamination that may cause difficulty during security enhancement. If the licensee understands this, it may provide facilities the opportunity to plan and prepare for unusual circumstances.

Influence of starter protein content on growth of dairy calves in an enhanced early nutrition program.

PubMed

Stamey, J A; Janovick, N A; Kertz, A F; Drackley, J K

2012-06-01

Our objectives were to determine the effect of starter crude protein (CP) content on growth of Holstein calves from birth to 10 wk of age in an enhanced early nutrition program, and to compare the enhanced program to a conventional milk replacer program. Calves (64 female, 25 male) were assigned to 3 treatments in a randomized block design: 1) conventional milk replacer (20% CP, 20% fat) plus conventional starter [19.6% CP, dry matter (DM) basis], 2) enhanced milk replacer (28.5% CP, 15% fat) plus conventional starter, and 3) enhanced milk replacer plus high-CP starter (25.5% CP, DM basis). Calves began treatments (n=29, 31, and 29 for treatments 1 to 3) at 3 d of age. Conventional milk replacer (12.5% solids) was fed at 1.25% of birth body weight (BW) as DM daily in 2 feedings from wk 1 to 5 and at 0.625% of birth BW once daily during wk 6. Enhanced milk replacer (15% solids) was fed at 1.5% of BW as DM during wk 1 and 2% of BW as DM during wk 2 to 5, divided into 2 daily feedings. During wk 6, enhanced milk replacer was fed at 1% of BW as DM once daily. Calves were weaned at d 42. Starter was available for ad libitum intake starting on d 3. Starter intake was greater for calves fed conventional milk replacer. For calves fed enhanced milk replacer, starter intake tended to be greater for calves fed enhanced starter. During the weaning period, enhanced starter promoted greater starter DM intake than the conventional starter. Over the 10-wk study, the average daily gain of BW (0.64, 0.74, and 0.80 kg/d) was greater for calves fed enhanced milk replacer with either starter and, for calves fed enhanced milk replacer, tended to be greater for calves fed high-CP starter. Rates of change in withers height, body length, and heart girth were greater for calves fed enhanced milk replacer but did not differ between starter CP concentrations. The postweaning BW for enhanced milk replacer treatments was greater for calves receiving the enhanced starter at wk 8 (73.7, 81.3, and 85.8 kg) and wk 10 (88.0, 94.9, and 99.9 kg). Starter CP content did not affect height, length, or heart girth within enhanced milk replacer treatments. Regression analysis showed that gain of BW during the first week postweaning (wk 7) increased with greater 3-d mean starter intake in the week before weaning. Starter with 25.5% CP (DM basis) provided modest benefits in starter intake (particularly around weaning) and growth for dairy calves in an enhanced early nutrition program compared with a conventional starter (19.6% CP). Copyright © 2012 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

MTU-pre-service teacher enhancement program. Final report, September 1992--May 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, C.S.; Yarroch, W.J.

1996-01-01

The MTU Pre-Service Teacher Enhancement Program was a two year extended project designed to introduce a select group of science and engineering undergraduate students, with good {open_quotes}people skills,{close_quotes} to the teaching profession. Participants were paid for their time spent with area teacher/mentors and were involved in a variety of in school activities, projects and observations to illustrate the teaching profession. They were encouraged to consider the teaching profession as a future career option. The student participants, however, were under no obligation to enter the Teacher Education Program at the conclusion of the program.

Metrics for the National SCADA Test Bed Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Craig, Philip A.; Mortensen, J.; Dagle, Jeffery E.

2008-12-05

The U.S. Department of Energy Office of Electricity Delivery and Energy Reliability (DOE-OE) National SCADA Test Bed (NSTB) Program is providing valuable inputs into the electric industry by performing topical research and development (R&D) to secure next generation and legacy control systems. In addition, the program conducts vulnerability and risk analysis, develops tools, and performs industry liaison, outreach and awareness activities. These activities will enhance the secure and reliable delivery of energy for the United States. This report will describe metrics that could be utilized to provide feedback to help enhance the effectiveness of the NSTB Program.

Outcomes from the Mount Sinai Social Work Leadership Enhancement Program: Evaluation and extrapolation.

PubMed

Nilsson, David; Wellington-Boyd, Anna

2006-01-01

This article presents an overview of outcomes from the Mount Sinai Leadership Enhancement Program as identified by previous program participants from Melbourne, Australia. These are categorised into: (1) Personal/professional, (2) Intra-organisational, (3) Interorganisational, and (4) International outcomes. Two illustrative examples are provided of international outcomes demonstrating how the ongoing commitment of Professor Epstein has extended and embedded the principles of practice-based research in Melbourne, and how the over-riding principles of the program have been applied by participants in establishing collaborative relationships with colleagues in our neighbouring South-East Asian region.

Enhancing organizational capacity to provide cancer control programs among Latino churches: design and baseline findings of the CRUZA Study.

PubMed

Allen, Jennifer D; Torres, Maria Idali; Tom, Laura S; Rustan, Sarah; Leyva, Bryan; Negron, Rosalyn; Linnan, Laura A; Jandorf, Lina; Ospino, Hosffman

2015-04-09

Faith-based organizations (FBOs) have been successful in delivering health promotion programs for African Americans, though few studies have been conducted among Latinos. Even fewer have focused on organizational change, which is required to sustain community-based initiatives. We hypothesized that FBOs serving Latinos would be more likely to offer evidence-based strategies (EBS) for cancer control after receiving a capacity enhancement intervention to implement health programs, and designed the CRUZA trial to test this hypothesis. This paper describes the CRUZA design and baseline findings. We identified Catholic parishes in Massachusetts that provided Spanish-language mass (n = 65). A baseline survey assessed organizational characteristics relevant to adoption of health programs, including readiness for adoption, "fit" between innovation and organizational mission, implementation climate, and organizational culture. In the next study phase, parishes that completed the baseline assessment will be recruited to a randomized cluster trial, with the parish as the unit of analysis. Both groups will receive a Program Manual and Toolkit. Capacity Enhancement parishes will also be offered technical support, assistance forming health committees and building inter-institutional partnerships, and skills-based training. Of the 49 parishes surveyed at baseline (75%), one-third (33%) reported having provided at least one health program in the prior year. However, only two program offerings were cancer-specific. Nearly one-fifth (18%) had an active health ministry. There was a high level of organizational readiness to adopt cancer control programs, high congruence between parish missions and CRUZA objectives, moderately conducive implementation climates, and organizational cultures supportive of CRUZA programming. Having an existing health ministry was significantly associated with having offered health programs within the past year. Relationships between health program offerings and other organizational characteristics were not statistically significant. Findings suggest that many parishes do not offer cancer control programs, yet many may be ready to do so. However, the perceptions about existing organizational practices and policies may not be conducive to program initiation. A capacity enhancement intervention may hold promise as a means of increasing health programming. The efficacy of such an intervention will be tested in phase two of this study.

Enhancement of Self-Monitoring in a Web-Based Weight Loss Program by Extra Individualized Feedback and Reminders: Randomized Trial

PubMed Central

Hutchesson, Melinda Jane; Tan, Chor Yin; Morgan, Philip; Callister, Robin

2016-01-01

Background Self-monitoring is an essential behavioral strategy for effective weight loss programs. Traditionally, self-monitoring has been achieved using paper-based records. However, technology is now more frequently used to deliver treatment programs to overweight and obese adults. Information technologies, such as the Internet and mobile phones, allow innovative intervention features to be incorporated into treatment that may facilitate greater adherence to self-monitoring processes, provide motivation for behavior change, and ultimately lead to greater weight loss success. Objective The objective of our study was to determine whether the consistency of self-monitoring differed between participants randomly assigned to a basic or an enhanced 12-week commercial Web-based weight loss program. Methods We randomly assigned a sample of 301 adults (mean age 42.3 years; body mass index 31.3 kg/m2; female 176/301, 58.5%) to the basic or enhanced group. The basic program included tools for self-monitoring (online food and exercise diary, and a weekly weigh-in log) with some feedback and reminders to weigh in (by text or email). The enhanced program included the basic components, as well as extra individualized feedback on self-monitoring entries and reminders (by text, email, or telephone) to engage with self-monitoring tools. We evaluated the level of self-monitoring by examining the consistency of self-monitoring of food, exercise, and weight during the 12 weeks. Consistency was defined as the number of weeks during which participants completed a criterion number of entries (ie, ≥3 days of online food or exercise diary records per week and ≥1 weigh-in per week). Results The enhanced group’s consistency of use of self-monitoring tools was significantly greater than that of the basic group throughout the 12 weeks (median consistency for food 8 vs 3 weeks, respectively, P<.001; for exercise 2.5 vs 1 weeks, respectively, P=.003). Conclusions Enhanced features, including additional individualized feedback and reminders, are effective in enhancing self-monitoring behaviors in a Web-based weight loss program. ClinicalTrial Australian New Zealand Clinical Trials Registry (ANZCTR): ACTRN12610000197033; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=335159 (Archived by WebCite at http://www.webcitation.org/6gCQdj21G) PMID:27072817

New Global Electron Density Observations from GPS-RO in the D- and E-Region Ionosphere

NASA Technical Reports Server (NTRS)

Wu, Dong L.

2017-01-01

A novel retrieval technique is developed for electron density (N(sub e)) in the D- and E-region (80-120 km) using the high-quality 50-Hz GPS radio occultation (GPS-RO) phase measurements. The new algorithm assumes a slow, linear variation in the F-region background when the GPS-RO passes through the D- and E-region, and extracts the N(sub e) profiles at 80-130 km from the phase advance signal caused by N(sub e). Unlike the conventional Abel function, the new approach produces a sharp N(sub e) weighting function in the lower ionosphere, and the N(sub e) retrievals are in good agreement with the IRI (International Reference Ionosphere) model in terms of monthly maps, zonal means and diurnal variations. The daytime GPS-RO N(sub e) profiles can be well characterized by the alpha-Chapman function of three parameters (N(sub mE), h(sub mE) and H), showing that the bottom of E-region is deepening and sharpening towards the summer pole. At high latitudes the monthly GPS-RO N(sub e) maps at 80-120 km reveal clear enhancement in the auroral zones, more prominent at night, as a result of energetic electron precipitation (EEP) from the outer radiation belt. The D-/E-region auroral N(sub e) is strongly correlated with K(sub p) on a daily basis. The new N(sub e) data allow further comprehensive analyses of the sporadic E (E(sub s)) phenomena in connection with the background N(sub e) in the E-region. The layered (2-10 km) and fluctuated (less than 2 km) E(sub s) components, namely N(sub e_Layer) than N(sub e_Pert), are extracted with respect to the background N( sub e_Region) on a profile-by-profile basis. The N(sub e_Layer) component has a strong but highly-refined peak at approximately 105 km, with an amplitude smaller than N(sub e_Region) approximately by an order of magnitude. The N(sub e_Pert) component, which was studied extensively in the past, is approximately 2 orders of magnitude weaker than N(sub e_Layer). Both N(sub e_Layer) and N(sub e_Pert) are subject to significant diurnal and semidiurnal variations, showing downward progression with local time in amplitude. The 11-year solar cycle dominates the N(sub e) interannual variations, showing larger N(sub e_Region) and N(sub e_Layer) but smaller N(sub e_Pert) amplitudes in the solar maximum years. Enhanced Ne profiles are often observed in the polar winter, showing good correlation with solar proton events (SPEs) and geomagnetic activity. The new methodology offers great potential for retrieving low N(sub e) in the D-region, where radio propagation and communication blackouts can occur due to enhanced ionization. For space weather applications it is recommended for GPSRO operations to raise the top of high-rate data acquisition to approximately 140 km in the future.

Non-governmental organization facilitation of a community-based nutrition and health program: Effect on program exposure and associated infant feeding practices in rural India.

PubMed

Singh, Veena; Ahmed, Saifuddin; Dreyfuss, Michele L; Kiran, Usha; Chaudhery, Deepika N; Srivastava, Vinod K; Ahuja, Ramesh C; Baqui, Abdullah H; Darmstadt, Gary L; Santosham, Mathuram; West, Keith P

2017-01-01

Integrated nutrition and health programs seek to reduce undernutrition by educating child caregivers about infant feeding and care. Data on the quality of program implementation and consequent effects on infant feeding practices are limited. This study evaluated the effectiveness of enhancing a nutrition and health program on breastfeeding and complementary-feeding practices in rural India. Utilizing a quasi-experimental design, one of the implementing districts of a Cooperative for Assistance and Relief Everywhere (CARE) nutrition and health program was randomly selected for enhanced services and compared with a district receiving the Government of India's standard nutrition and health package alone. A cohort of 942 mother-child dyads was longitudinally followed from birth to 18 months. In both districts, the evaluation focused on responses to services delivered by community-based nutrition and health care providers [anganwadi workers (AWWs) and auxiliary nurse midwives (ANMs)]. The CARE enhanced program district showed an improvement in program coverage indicators (e.g., contacts, advice) through outreach visits by both AWWs (28.8-59.8% vs. 0.7-12.4%; all p<0.05) and ANMs (8.6-46.2% vs. 6.1-44.2%; <0.05 for ages ≥6 months). A significantly higher percentage of child caregivers reported being contacted by the AWWs in the CARE program district (20.5-45.6% vs. 0.3-21.6%; p<0.05 for all ages except at 6months). No differences in ANM household contacts were reported. Overall, coverage remained low in both areas. Less than a quarter of women received any infant feeding advice in the intervention district. Earlier and exclusive breastfeeding improved with increasing number or quality of visits by either level of health care provider (OR: 2.04-3.08, p = <0.001), after adjusting for potentially confounding factors. Socio-demographic indicators were the major determinants of exclusive breastfeeding up to 6 month and age-appropriate complementary-feeding practices thereafter in the program-enhanced but not comparison district. An enhanced nutrition and health intervention package improved program exposure and associated breastfeeding but not complementary-feeding practices, compared to standard government package. ClinicalTrials.gov NCT00198835.

Using environmental public health tracking to identify community targets for public health actions in childhood lead poisoning in Wisconsin.

PubMed

Berney, Dawn; Camponeschi, Jenny; Coons, Marjorie; Creswell, Paul D; Schirmer, Joe; Walsh, Reghan

2015-01-01

In an effort to improve the ability of local public health departments to target resources to the highest need regions, the Wisconsin Environmental Public Health Tracking (WI EPHT) Program worked to enhance its public portal to benefit the Wisconsin Childhood Lead Poisoning Prevention Program (WCLPPP) and other programs. The WI EPHT Program conducted this enhancement in collaboration with WCLPPP. The WI EPHT enhanced public portal is the next phase of Wisconsin's ongoing efforts in environmental public health tracking. As part of this process, this new mapping application includes mapping capacity that provides information on childhood lead testing and results at county and census tract levels in Wisconsin. The WI EPHT Program will update its public portal to have the capability to map data at a subcounty level (ie, census tract or zip code) for some data topics when such data are available. This tool is available to local public health departments and other public health organizations throughout Wisconsin as a resource to identify communities most affected by the Centers for Disease Control and Prevention's new guidelines with regard to childhood lead poisoning. The collaboration between WI EPHT and WCLPPP on updating and enhancing the portal exemplifies the power of environmental health data to inform a more accurate understanding of public health problems.

Rural Programs: Vocational Education Resource Package.

ERIC Educational Resources Information Center

Evaluation and Training Inst., Los Angeles, CA.

Designed to assist community college administrators and faculty in enhancing vocational education programs and services, this resource package on rural college programs contains information about successful program strategies and ideas currently in use in vocational education programs at rural schools within the California Community Colleges…

A Framework for Examining the Utility of Technology-Enhanced Items

ERIC Educational Resources Information Center

Russell, Michael

2016-01-01

Interest in and use of technology-enhanced items has increased over the past decade. Given the additional time required to administer many technology-enhanced items and the increased expense required to develop them, it is important for testing programs to consider the utility of technology-enhanced items. The Technology-Enhanced Item Utility…

Structural Technology Evaluation Analysis Program (STEAP). Task Order 0029: Thermal Stability of Fatigue Life-Enhanced Structures

DTIC Science & Technology

2012-01-01

and c, we were able to obtain Figure 21: Intensity and Pressure Temporal Profiles Calculated from Pressure Model 0 20 40 60 80 100 0 2 4 6 8...August 2008 – 31 January 2012 4 . TITLE AND SUBTITLE STRUCTURAL TECHNOLOGY EVALUATION ANALYSIS PROGRAM (STEAP) Task Order 0029: Thermal...Stability of Fatigue Life-Enhanced Structures 5a. CONTRACT NUMBER FA8650-04-D-3446-0029 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 62201F 6

Employment, Training, and Literacy Enhancement Act of 1997. Report of the Committee on Education and the Workforce, House of Representatives, on H.R. 1385 Together with Additional and Dissenting Views [Including Cost Estimate of the Congressional Budget Office], 105th Congress, 1st Session.

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. House Committee on Education and the Workforce.

This document contains the text of the Employment, Training, and Literacy Enhancement Act of 1997, as amended by committee, including the titles that cover the following: general provisions; employment and training programs for disadvantaged youth; federally administered programs; adult education programs; miscellaneous provisions; the State Human…

Comparative study of an externship program versus a corporate-academic cooperation program for enhancing nursing competence of graduating students

PubMed Central

2013-01-01

Background New graduates report intense stress during the transition from school to their first work settings. Managing this transition is important to reduce turnover rates. This study compared the effects of an externship program and a corporate-academic cooperation program on enhancing junior college students’ nursing competence and retention rates in the first 3 months and 1 year of initial employment. Methods This two-phase study adopted a pretest and posttest quasi-experimental design. All participants were graduating students drawn from a 5-year junior nursing college in Taiwan. There were 19 and 24 students who participated in the phase I externship program and phase II corporate-academic cooperation program, respectively. The nursing competence of the students had to be evaluated by mentors within 48 hours of practicum training and after practicum training. The retention rate was also surveyed at 3 months and 1 year after beginning employment. Results Students who participated in the corporate-academic cooperation program achieved a statistically significant improvement in nursing competence and retention rates relative to those who participated in the externship program (p < 0.01 and p < 0.05, respectively). Conclusions The corporate-academic cooperation program facilitates the transition of junior college nursing students into independent staff nurses, enhances their nursing competence, and boosts retention rates. PMID:23945287

A Leadership Education and Development Program for Clinical Nurses.

PubMed

Fitzpatrick, Joyce J; Modic, Mary Beth; Van Dyk, Jennifer; Hancock, K Kelly

2016-11-01

The Leadership Education and Development (LEAD) Program was designed to transform care at the bedside by empowering clinical nurses as leaders. The heart of LEAD was enhancing communication skills of clinical nurses with clinical colleagues and, most importantly, patients and families. Key concepts of leadership/management were included: personal awareness, personal leadership skills/abilities, leading change, leading others individually and in teams, enhancing the patient/provider experience, and the leadership role in outcomes management. A quantitative, longitudinal, survey design was used with 2 cohorts. The program consisted of six 4-hour sessions for 3 to 6 months. Leadership practices were measured before program implementation, at the end of the program, and 3 months after program completion. There were significant increases in leadership practices sustained 3 months after program completion. A range of other outcome measures was included. There is a need for additional leadership development programs for clinical nurses.

A human-centered framework for innovation in conservation incentive programs.

PubMed

Sorice, Michael G; Donlan, C Josh

2015-12-01

The promise of environmental conservation incentive programs that provide direct payments in exchange for conservation outcomes is that they enhance the value of engaging in stewardship behaviors. An insidious but important concern is that a narrow focus on optimizing payment levels can ultimately suppress program participation and subvert participants' internal motivation to engage in long-term conservation behaviors. Increasing participation and engendering stewardship can be achieved by recognizing that participation is not simply a function of the payment; it is a function of the overall structure and administration of the program. Key to creating innovative and more sustainable programs is fitting them within the existing needs and values of target participants. By focusing on empathy for participants, co-designing program approaches, and learning from the rapid prototyping of program concepts, a human-centered approach to conservation incentive program design enhances the propensity for discovery of novel and innovative solutions to pressing conservation issues.

Educating Patient Educators: Enhancing Instructional Effectiveness in Physical Therapy for Low Back Pain Patients.

ERIC Educational Resources Information Center

Kerssens, Jan J.; Sluijs, Emmy M.; Verhaak, Peter F. M.; Knibbe, Hanneke J.; Hermans, Irma M. J.

1999-01-01

Examines the effectiveness of a training program designed for physical therapists (N=19) to aid them in the enhancement of patient education. Five therapist-skills were tested. After the training only a minority of the trained skills appeared to have improved. Results show that the training program was not very effective. (Author/MKA)

Choice modeling: public preferences for enhancing benefits from private forests in the Adirondacks

Treesearch

Donald F. Dennis; Mark J. Twery

2007-01-01

Recognizing the importance of private land in meeting society's needs for forest-related benefits, public agencies fund programs that provide aid to private landowners to enhance public benefits derived from these lands. This may include technical help, education, tax incentives, and cost-share programs for various management activities. It is important that...

NASTRAN maintenance and enhancement experiences

NASA Technical Reports Server (NTRS)

Schmitz, R. P.

1975-01-01

The current capability is described which includes isoparametric elements, optimization of grid point sequencing, and eigenvalue routine. Overlay and coding errors were corrected for cyclic symmetry, transient response, and differential stiffness rigid formats. Error corrections and program enhancements are discussed along with developments scheduled for the current year and a brief description of analyses being performed using the program.

Enhancing Academic Success: A Bilingual Freshman Year. AIR 1992 Annual Forum Paper.

ERIC Educational Resources Information Center

Ronco, Sharron

This paper provides an assessment of the Inter-American Science and Humanities Program, a program of the University of Texas, El Paso, which allowed students from northern Mexico to take their freshman level courses in Spanish while receiving instruction designed to rapidly enhance English language skills. The paper assesses the effectiveness of…

School-Related Factors Contributing to the Delivery Enhancement of the Special Science Program in Western Visayas, Philippines

ERIC Educational Resources Information Center

Bangcaya, Porferio S.; Alejandro, Grecebio Jonathan D.

2015-01-01

In this mixed-method study, the secondary schools in Western Visayas, Philippines offering special science program (SSP) were assessed as basis for delivery enhancement. The SSP along student-related factors and the extent of implementation in the areas of curriculum and instruction, laboratory facilities, and administration in terms of the…

Improving Dyadic Coping in Couples with a Stress-Oriented Approach: A 2-Year Longitudinal Study

ERIC Educational Resources Information Center

Bodenmann, Guy; Pihet, Sandrine; Shantinath, Shachi D.; Cina, Annette; Widmer, Kathrin

2006-01-01

This study sought to assess the effectiveness of a marital distress prevention program for couples by examining how marital quality, especially marital competencies such as dyadic coping, could be improved by means of a prevention program focusing on the enhancement of coping resources (Couples Coping Enhancement Training). The study consisted of…

Creating and Maintaining Safe College Campuses: A Sourcebook for Enhancing and Evaluating Safety Programs

ERIC Educational Resources Information Center

Jackson, Jerlando F. L., Ed.; Terrell, Melvin Cleveland, Ed.

2007-01-01

This book serves as a sourcebook to enhance and evaluate safety programs, generate new solutions and interventions, comply with new legislation, and present practical steps and guidelines to establish best practices. It pays particular attention to the factors that may give rise to crime, considering high-risk drinking and examining the…

Development of Program for Enhancing the Ideal Desirable Characteristic of Basic School Administrators

ERIC Educational Resources Information Center

Khakhlong, Chettha; Julsuwan, Suwat; Somprach, Kanokorn; Khangpheng, Samrit

2015-01-01

The objective of this research is to develop a program for enhancing ideal desirable characteristic of basic school administrators. An in-depth interview was done with experts. The opinions of school administrators, assistant school administrators, and teachers as the chiefs of academic work were found out. A total of 330 persons participated in…

Short Term Intervention Model for Enhancing Divergent Thinking among School Aged Children

ERIC Educational Resources Information Center

Doron, Eyal

2016-01-01

Creative ability can be developed and improved through intervention and training. This study presents a unique and innovative intervention program for enhancing creative thinking among children, focusing on divergent thinking skills. The program was designed as a short-term (10 weeks) training and conducted with 150 school students ranging in age…

Fast Track. Summer Academic Skills Enhancement Program, 1993. Final Evaluation Report.

ERIC Educational Resources Information Center

Donaldson, William S.

The Summer Academic Skills Enhancement Program (SASEP) was offered in June-August 1993 to provide Job Training Partnership Act (JTPA) clients with the reading comprehension and language mechanics skills required for employment in entry-level positions. A total of 125 referred clients were enrolled into both of two remedial courses of study.…

Career Advancement, Career Enhancement, and Personal Growth of Pepperdine University's Educational Leadership Academy Graduate Program Alumni

ERIC Educational Resources Information Center

Nichols, Ruth I.

2012-01-01

The purpose of this phenomenological study was two-fold: (a) to explore and describe the perceived impact of Pepperdine University's Educational Leadership Academy (ELA) on 2003-2006 ELA graduates' career advancement, career enhancement, and personal growth; and (b) to obtain ELA graduates' suggestions for ELA program improvement to better prepare…

Sustainability of an Integrated Adventure-Based Training and Health Education Program to Enhance Quality of Life Among Chinese Childhood Cancer Survivors: A Randomized Controlled Trial.

PubMed

Chung, Oi Kwan Joyce; Li, Ho Cheung William; Chiu, Sau Ying; Ho, Ka Yan; Lopez, Violeta

2015-01-01

Physical activity is of paramount importance to enhance the quality of life of childhood cancer survivors. The objectives of this study were to examine the sustainability, feasibility, and acceptability of an adventure-based training and health education program in changing the exercise behavior and enhancing the physical activity levels, self-efficacy, and quality of life of childhood cancer survivors. A follow-up study (12 and 18 months) of a previous study was conducted. Participants in the experimental group (n = 33) joined a 4-day integrated adventure-based training and health education program. The control group (n = 36) received the standard medical care. Changes in exercise behavior, levels of physical activity, self-efficacy, and quality of life were assessed from the time of recruitment, and at 12 and 18 months after starting the intervention. Process evaluation was conducted to determine whether the program was feasible and acceptable to participants. From baseline to 18 months after the intervention, the experimental group reported statistically significant differences in the stages of change in physical activity and higher levels of physical activity, self-efficacy, and quality of life than did the control group. The results of process evaluation revealed that the program was both feasible and acceptable to participants. The program was found to have substantial effects on enhancing the physical activity levels, self-efficacy, and quality of life of childhood cancer survivors over at least 18 months. Healthcare professionals should consider adopting such programs to promote the regular physical activity among childhood cancer survivors.

Enhancing the Transition to Kindergarten: A Randomized Trial to Test the Efficacy of the “Stars” Summer Kindergarten Orientation Program

PubMed Central

Berlin, Lisa J.; Dunning, Rebecca D.; Dodge, Kenneth A.

2010-01-01

This randomized trial tested the efficacy of an intensive, four-week summer program designed to enhance low-income children's transition to kindergarten (n's = 60 program children, 40 controls). Administered in four public schools, the program focused on social competence, pre-literacy and pre-numeracy skills, school routines, and parental involvement. Hierarchical linear modeling indicated that the program significantly improved teachers’ ratings of (a) the transition to the social aspect of kindergarten for girls (but not boys); and (b) the transition to kindergarten routines for the subgroup of children who had the same teacher for kindergarten as for the summer program. Findings are discussed in terms of practices and policies for supporting children's transition to school. PMID:21969767

Process evaluation of the project P.A.T.H.S. (secondary 2 program): findings based on the co-walker scheme.

PubMed

Shek, Daniel T L; Tam, Suet-yan

2009-01-01

To understand the implementation quality of the Tier 1 Program (Secondary 2 Curriculum) of the P.A.T.H.S. Project, process evaluation was carried out by co-walkers through classroom observation of 195 units in 131 schools. Results showed that the overall level of program adherence was generally high with an average of 84.55%, and different factors of the implementation process were evaluated as positive. Quality of program implementation and achievement of program objectives were predicted by students' participation and involvement, strategies to enhance students' motivation, opportunity for reflection, time management, and class preparation. Success in program implementation was predicted by students' participation and involvement, classroom control, interactive delivery method, strategies to enhance students' motivation, opportunity for reflection, and lesson preparation.

33 CFR 157.430 - Enhanced survey requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Enhanced survey requirements. 157... § 157.430 Enhanced survey requirements. Beginning at each tank vessel's next regularly scheduled drydock... tank vessel owner or operator shall— (a) Implement an enhanced survey program that complies with the...

33 CFR 157.430 - Enhanced survey requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Enhanced survey requirements. 157... § 157.430 Enhanced survey requirements. Beginning at each tank vessel's next regularly scheduled drydock... tank vessel owner or operator shall— (a) Implement an enhanced survey program that complies with the...

33 CFR 157.430 - Enhanced survey requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Enhanced survey requirements. 157... § 157.430 Enhanced survey requirements. Beginning at each tank vessel's next regularly scheduled drydock... tank vessel owner or operator shall— (a) Implement an enhanced survey program that complies with the...

33 CFR 157.430 - Enhanced survey requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Enhanced survey requirements. 157... § 157.430 Enhanced survey requirements. Beginning at each tank vessel's next regularly scheduled drydock... tank vessel owner or operator shall— (a) Implement an enhanced survey program that complies with the...

33 CFR 157.430 - Enhanced survey requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Enhanced survey requirements. 157... § 157.430 Enhanced survey requirements. Beginning at each tank vessel's next regularly scheduled drydock... tank vessel owner or operator shall— (a) Implement an enhanced survey program that complies with the...

Local Climate and Energy Program Model Design Guide: Enhancing Value and Creating Lasting Programs

EPA Pesticide Factsheets

Created for local climate and clean energy program implementers, learn how programs create and deliver value to target audiences and partners, how to raise revenue, and how they can operate cost effectively.

A Program on Biochemical and Biomedical Engineering.

ERIC Educational Resources Information Center

San, Ka-Yiu; McIntire, Larry V.

1989-01-01

Presents an introduction to the Biochemical and Biomedical Engineering program at Rice University. Describes the development of the academic and enhancement programs, including organizational structure and research project titles. (YP)

Programs for Watershed-Plus phase for rainfed regions in India

NASA Astrophysics Data System (ADS)

Ramachandran, Kausalya; Ramakrishna, Y. S.

2006-12-01

Watershed-based development is the strategy for sustainable growth in the vast rain-fed regions of India since 1980s to enhance agricultural production, conservation of natural resources and raising rural livelihood of farming communities. Although soil and water conservation was initially the primary objective of watershed program that saw large public investment since inception, later its focus shifted to principles of equity and enhancing rural livelihood opportunities and more recently to sustainable development since mid-1990s. At present a major emphasis under watershed program is the regeneration of degraded fragile lands in rain-fed regions. Several noteworthy watershed programs have been carried out since inception that have yielded sterling results while many others have yielded little by way of unbalanced development because of improper characterization of watersheds and poor project planning and implementation. Tools of Geomatics like satellite data, GIS and GPS besides conventional ones like field survey, topographical and cadastral maps along with traditional multi-disciplinary methods like PRA, soil and water analysis, socio-economic survey etc. provide insight into characterization of watersheds, project formulation and proper implementation of such development programs. The present paper illustrates the methodology for characterization of watersheds using the tools of Geomatics on one hand, besides exhibiting its utility for scaling-out the program benefits like sustaining higher agricultural productivity, enhancing irrigation efficiency, equity, enhanced rural livelihood opportunities, women empowerment, drought-proofing etc. during Watershed-Plus phase in the coming decades, on the other.

Napa River Sediment TMDL Implementation and Habitat Enhancement Project

EPA Pesticide Factsheets

Information about the SFBWQP Napa River Sediment TMDL Implementation and Habitat Enhancement Project, part of an EPA competitive grant program to improve SF Bay water quality focused on restoring impaired waters and enhancing aquatic resources.

Enhancements to the Branched Lagrangian Transport Modeling System

USGS Publications Warehouse

Jobson, Harvey E.

1997-01-01

The Branched Lagrangian Transport Model (BLTM) has received wide use within the U.S. Geological Survey over the past 10 years. This report documents the enhancements and modifications that have been made to this modeling system since it was first introduced. The programs in the modeling system are arranged into five levels?programs to generate time-series of meteorological data (EQULTMP, SOLAR), programs to process time-series data (INTRP, MRG), programs to build input files for transport model (BBLTM, BQUAL2E), the model with defined reaction kinetics (BLTM, QUAL2E), and post processor plotting programs (CTPLT, CXPLT). An example application is presented to illustrate how the modeling system can be used to simulate 10 water-quality constituents in the Chattahoochee River below Atlanta, Georgia.

Parents as Partners Program.

ERIC Educational Resources Information Center

Ryan, Thomas E.

1992-01-01

In September 1990, three programs (Family Study Institute, Saturday School Programs, and Evening Programs) to strengthen and improve parent-school partnerships and enhance communication were instituted in a racially integrated school district in Cook County, Illinois. Evaluation findings showed that parental involvement significantly enhanced…

Gaining a Professional Edge.

ERIC Educational Resources Information Center

Jonen, Ruth; Griffith, Phyllis

1998-01-01

The American School Food Service Association has two recognition programs: the recently revised School Foodservice and Nutrition Certification Program and the new School Foodservice and Nutrition Specialist Credentialing Program. The credentialing program was created to enhance school food-service professionals' image and improve their management…

ORD Water Quality Research Program Mid-Cycle Review - June 2009

EPA Pesticide Factsheets

The Board of Scientific Counselors (BOSC) completed a mid-cycle review of the Office of Research and Development’s (ORD) Water Quality Research Program (WQRP), focusing on Agency efforts to enhance the program following the 2006 BOSC program review.

Credit Enhancement Overview Guide

DOE Office of Scientific and Technical Information (OSTI.GOV)

Financing Solutions Working Group

2014-01-01

Provides considerations for state and local policymakers and energy efficiency program administrators designing and implementing successful credit enhancement strategies for residential and commercial buildings.

Improving Student Learning through the Use of Classroom Quizzes: Three Years of Evidence from the Columbia Middle School Project

ERIC Educational Resources Information Center

Agarwal, Pooja K.; Roediger, Henry L., III; McDaniel, Mark A.; McDermott, Kathleen B.

2010-01-01

In this study, the authors examined whether a test-enhanced learning program, integrated with daily classroom practices, is effective in a middle school setting. Specifically, they implemented and experimentally evaluated a test-enhanced learning program in 6th-8th grade Social Studies, English, Science, and Spanish classes. Although laboratory…

HaLT2- an enhanced lumber grading trainer

Treesearch

Powsiri Klinkhachorn; Charles Gatchell; Charles McMillin; Ravi Kothari; Dennis Yost

1992-01-01

This paper reports on HaLT2, an improved version of HaLT (Hardwood Lumber Traning Program)- a computer program that provides training in lumber grading. The newly added enhancements In HaLT2 will provide training for both novice and experienced hardwood lumber graders in accordance with National Hardwood Lumber Assodation (NHLA) rules. HaLT2 is more accurate, easier to...

Families Finding the Balance: A Parent Handbook. We Can! Ways to Enhance Children's Activity & Nutrition.

ERIC Educational Resources Information Center

US Department of Health and Human Services, 2005

2005-01-01

We Can! (Ways to Enhance Children's Activity & Nutrition) is a new public education outreach program designed to help children 8-13 years old stay at a healthy weight through improving food choices, increasing physical activity, and reducing screen time. The program is a collaboration of four Institutes of the National Institutes of Health (NIH):…

The Role of a Museum-Based Science Education Program in Promoting Content Knowledge and Science Motivation

ERIC Educational Resources Information Center

Martin, Andrew J.; Durksen, Tracy L.; Williamson, Derek; Kiss, Julia; Ginns, Paul

2016-01-01

Informal learning settings such as museums have been identified as opportunities to enhance students' knowledge and motivation in science and to optimize the connection between science and everyday life. The present study assessed the role of a self-paced science education program (situated in a medical science museum) in enhancing students'…

Enhancement of Learning through an Integrated Teaching Environment (Project ELITE) Special Alternative Instruction Program. Final Evaluation Report, 1992-93. OER Report.

ERIC Educational Resources Information Center

Ventouratos, Despina

Enhancement of Learning through an Integrated Teaching Environment (Project ELITE), a federally-funded bilingual education program, served 233 students of limited English proficiency in two high schools in Queens (New York) in its second year of operation. Participating students received instruction in English as a Second Language (ESL),…

Development and Application of a Computer Simulation Program to Enhance the Clinical Problem-Solving Skills of Students.

ERIC Educational Resources Information Center

Boh, Larry E.; And Others

1987-01-01

A project to (1) develop and apply a microcomputer simulation program to enhance clinical medication problem solving in preclerkship and clerkship students and (2) perform an initial formative evaluation of the simulation is described. A systematic instructional design approach was used in applying the simulation to the disease state of rheumatoid…

A theory-informed approach to mental health care capacity building for pharmacists.

PubMed

Murphy, Andrea L; Gardner, David M; Kutcher, Stan P; Martin-Misener, Ruth

2014-01-01

Pharmacists are knowledgeable, accessible health care professionals who can provide services that improve outcomes in mental health care. Various challenges and opportunities can exist in pharmacy practice to hinder or support pharmacists' efforts. We used a theory-informed approach to development and implementation of a capacity-building program to enhance pharmacists' roles in mental health care. Theories and frameworks including the Consolidated Framework for Implementation Research, the Theoretical Domains Framework, and the Behaviour Change Wheel were used to inform the conceptualization, development, and implementation of a capacity-building program to enhance pharmacists' roles in mental health care. The More Than Meds program was developed and implemented through an iterative process. The main program components included: an education and training day; use of a train-the-trainer approach from partnerships with pharmacists and people with lived experience of mental illness; development of a community of practice through email communications, a website, and a newsletter; and use of educational outreach delivered by pharmacists. Theories and frameworks used throughout the program's development and implementation facilitated a means to conceptualize the component parts of the program as well as its overall presence as a whole from inception through evolution in implementation. Using theoretical foundations for the program enabled critical consideration and understanding of issues related to trialability and adaptability of the program. Theory was essential to the underlying development and implementation of a capacity-building program for enhancing services by pharmacists for people with lived experience of mental illness. Lessons learned from the development and implementation of this program are informing current research and evolution of the program.

Social marketing principles enhance enrollment in the cash and counseling demonstration and evaluation.

PubMed

Simon-Rusinowitz, Lori; Mahoney, Kevin J; Marks, Lori N; Simone, Kristin; Zacharias, B Lee

2009-01-01

Using focus group data, this article discusses the use of social marketing principles to enhance enrollment in the Cash and Counseling Demonstration and Evaluation (CCDE). Focus groups were conducted in person and by conference call in two CCDE states, Arkansas and Florida. In Florida, Department of Elder Affairs and Developmental Services Program (DS) staff participated in seven focus groups. In Arkansas, four focus groups were conducted with professionals likely to come into contact with Medicaid consumers who are eligible for Arkansas' cash option program. Focus group transcripts were coded according to the project research questions. Several important lessons emerged including the importance of(a) conducting process evaluation activities, such as the social marketing focus groups, early during program implementation; (b) using multiple approaches and contacts to inform potential consumers and their families about a new, complex program; (c) carefully selecting and training personnel to conduct outreach and enrollment activities; and (d) developing specific messages to include in marketing the cash option. Using social marketing principles to examine CCDE enrollment has provided important information to enhance this program.

Experiments in evaluation capacity building: Enhancing brain disorders research impact in Ontario.

PubMed

Nylen, Kirk; Sridharan, Sanjeev

2017-05-08

This paper is the introductory paper on a forum on evaluation capacity building for enhancing impacts of research on brain disorders. It describes challenges and opportunities of building evaluation capacity among community-based organizations in Ontario involved in enhancing brain health and supporting people living with a brain disorder. Using an example of a capacity building program called the "Evaluation Support Program", which is run by the Ontario Brain Institute, this forum discusses multiple themes including evaluation capacity building, evaluation culture and evaluation methodologies appropriate for evaluating complex community interventions. The goal of the Evaluation Support Program is to help community-based organizations build the capacity to demonstrate the value that they offer in order to improve, sustain, and spread their programs and activities. One of the features of this forum is that perspectives on the Evaluation Support Program are provided by multiple stakeholders, including the community-based organizations, evaluation team members involved in capacity building, thought leaders in the fields of evaluation capacity building and evaluation culture, and the funders. Copyright © 2017. Published by Elsevier Ltd.

Enhancing empowerment in eating disorder prevention: Another examination of the REbeL peer education model.

PubMed

Breithaupt, Lauren; Eickman, Laura; Byrne, Catherine E; Fischer, Sarah

2017-04-01

Previously validated eating disorder (ED) prevention programs utilize either a targeted or universal approach. While both approaches have shown to be efficacious, implementing either style of program within a school setting remains a challenge. The current study describes an enhanced version of REbeL, a module based, continuous ED prevention program which utilizes a self-selection model of prevention in high school settings. The purpose of this study was to determine if an enhanced empowerment model of REbeL could increase feelings of empowerment and reduce eating disorder risk. We also aimed to assess the feasibility and acceptability of the intervention. High school peer-educators self-selected into the semi-manualized dissonance based intervention. Following feedback from a pilot trailed, enhanced peer-led group activities, designed to critique the thin ideal and designed to empower macro-changes in societal structures that emphasize the thin ideal, were added. The study (N=83) indicates that the program appears to be effective at reducing eating disorder risk factors and increasing empowerment. Participants reported reductions in body checking and internalization of the thin ideal. Copyright © 2016 Elsevier Ltd. All rights reserved.

Developing nurse leaders: a program enhancing staff nurse leadership skills and professionalism.

PubMed

Abraham, Pauline J

2011-01-01

This study aims to determine whether participation in the Nursing Leadership Perspectives Program (NLPP) at Mayo Clinic in Rochester, Minnesota, produced a change in leadership skills, increased professional activities, leadership promotion, and retention rates of participants. The NLPP is an educational program designed to enhance leadership skills and promote professionalism of registered nurses. The 6-month program provides participants with theoretical knowledge, core competencies, and opportunities to practice application of leadership skills. Outcome metrics were collected from registered nurses who completed the program (n = 15). Data analysis included descriptive and nonparametric methods. Participants reported statistically significant changes in their leadership skills after participation in the program (P = .007) on the Leadership Practices Inventory. Changes in professional behavior were also statistically significant as rated by the Nursing Activity Scale (P = .001). Participants demonstrated a change in leadership skills and professional behavior following the program.

Enhancing Dating Attitudes through Peer Education as a Date Rape Prevention Strategy.

ERIC Educational Resources Information Center

Holcomb, Derek R.; Seehafer, Roger W.

1995-01-01

Presents program development and peer education training considerations for programs that attempt to influence healthy attitudes toward dating and preventing date rape. The paper discusses the program's theoretical foundations, goal determination, mixed-gender programs, themes students raise during programs, the consensual sex scenario as a…

76 FR 5157 - Public Water Supply Supervision Program; Program Revision for the State of Alaska

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-28

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9259-6] Public Water Supply Supervision Program; Program... Water Supply Supervision Primacy Program. Alaska has adopted regulations analogous to EPA's Stage 2 Disinfectants and Disinfection Byproducts Rule; Long Term 2 Enhanced Surface Water Treatment Rule; and Lead and...

78 FR 42945 - Public Water Supply Supervision Program; Program Revision for the State of Oregon

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-18

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9834-9] Public Water Supply Supervision Program; Program... Water Supply Supervision Primacy Program. Oregon has adopted regulations analogous to EPA's Stage 2 Disinfectants and Disinfection Byproducts Rule; Long Term 2 Enhanced Surface Water Treatment Rule; Ground Water...

Programs for Engagement and Enhancement. Professional File. Article 131, Spring 2013

ERIC Educational Resources Information Center

Crisp, Gloria; Palacios, Lisa; Kaulfus, John

2013-01-01

The following article describes programs used by universities and colleges to engage students; these programs include mentoring, learning communities, and first-year success courses and programs. We begin with a brief overview of student development theory, program descriptions and citations, and article summaries for key references. Next, we…

Development Impact Assessment Highlights Co-benefits of GHG Mitigation Actions

DOE Office of Scientific and Technical Information (OSTI.GOV)

2016-06-01

This EC-LEDS document describes the Development Impact Assessment (DIA) process that explores interactions between development goals and the low emission development strategies. DIA aims to support informed decision-making by considering how policies and programs intended to meet one goal may impact other development priorities. Enhancing Capacity for Low Emission Development Strategies (EC-LEDS) is a flagship U.S. government-led effort that assists countries in developing and implementing LEDS. The program enhances partner country efforts by providing targeting technical assistance and building a shared global knowledge base on LEDS. is a flagship U.S. government-led effort that assists countries in developing and implementing LEDS.more » The program enhances partner country efforts by providing targeting technical assistance and building a shared global knowledge base on LEDS.« less

Goddard Space Flight Center: 1994 Maryland/GSFC Earth and Environmental Science Teacher Ambassador Program

NASA Technical Reports Server (NTRS)

Latham, James

1995-01-01

The Maryland/Goddard Space Flight Center (GSFC) Earth and Environmental Science Teacher Ambassador Program was designed to enhance classroom instruction in the Earth and environmental science programs in the secondary schools of the state of Maryland. In October 1992, more than 100 school system administrators from the 24 local Maryland school systems, the Maryland State Department of Education, and the University of Maryland met with NASA GSFC scientists and education officers to propose a cooperative state-wide secondary school science teaching enhancement initiative.

Particle and gaseous emissions from individual diesel and CNG buses

NASA Astrophysics Data System (ADS)

Hallquist, Å. M.; Jerksjö, M.; Fallgren, H.; Westerlund, J.; Sjödin, Å.

2012-10-01

In this study size-resolved particle and gaseous emissions from 28 individual diesel-fuelled and 7 compressed natural gas (CNG)-fuelled buses, selected from an in-use bus fleet, were characterised for real-world dilution scenarios. The method used was based on using CO2 as a tracer of exhaust gas dilution. The particles were sampled by using an extractive sampling method and analysed with high time resolution instrumentation EEPS (10 Hz) and CO2 with non-dispersive infrared gas analyser (LI-840, LI-COR Inc. 1 Hz). The gaseous constituents (CO, HC and NO) were measured by using a remote sensing device (AccuScan RSD 3000, Environmental System Products Inc.). Nitrogen oxides, NOx, were estimated from NO by using default NO2/NOx ratios from the road vehicle emission model HBEFA 3.1. The buses studied were diesel-fuelled Euro II-V and CNG-fuelled Enhanced Environmental Friendly Vehicles (EEVs) with different after-treatment, including selective catalytic reduction (SCR), exhaust gas recirculation (EGR) and with and without diesel particulate filter (DPF). The primary driving mode applied in this study was accelerating mode. However, regarding the particle emissions also a constant speed mode was analysed. The investigated CNG buses emitted on average higher number of particles but less mass compared to the diesel-fuelled buses. Emission factors for number of particles (EFPN) were EFPN, DPF = 8.0 ± 3.1 × 1014, EFPN, no DPF =2.8 ± 1.6 × 1015 and EFPN, CNG = 7.8 ± 5.7 × 1015 (kg fuel-1). In the accelerating mode size-resolved EFs showed unimodal number size distributions with peak diameters of 70-90 nm and 10 nm for diesel and CNG buses, respectively. For the constant speed mode bimodal average number size distributions were obtained for the diesel buses with peak modes of ~10 nm and ~60 nm. Emission factors for NOx expressed as NO2 equivalents for the diesel buses were on average 27 ± 7 g (kg fuel)-1 and for the CNG buses 41 ± 26 g (kg fuel)-1. An anti-relationship between EFNOx and EFPM was observed especially for buses with no DPF and there was a positive relationship between EFPM and EFCO.

Particle and gaseous emissions from individual diesel and CNG buses

NASA Astrophysics Data System (ADS)

Hallquist, Å. M.; Jerksjö, M.; Fallgren, H.; Westerlund, J.; Sjödin, Å.

2013-05-01

In this study size-resolved particle and gaseous emissions from 28 individual diesel-fuelled and 7 compressed natural gas (CNG)-fuelled buses, selected from an in-use bus fleet, were characterised for real-world dilution scenarios. The method used was based on using CO2 as a tracer of exhaust gas dilution. The particles were sampled by using an extractive sampling method and analysed with high time resolution instrumentation EEPS (10 Hz) and CO2 with a non-dispersive infrared gas analyser (LI-840, LI-COR Inc. 1 Hz). The gaseous constituents (CO, HC and NO) were measured by using a remote sensing device (AccuScan RSD 3000, Environmental System Products Inc.). Nitrogen oxides, NOx, were estimated from NO by using default NO2/NOx ratios from the road vehicle emission model HBEFA3.1. The buses studied were diesel-fuelled Euro III-V and CNG-fuelled Enhanced Environmentally Friendly Vehicles (EEVs) with different after-treatment, including selective catalytic reduction (SCR), exhaust gas recirculation (EGR) and with and without diesel particulate filter (DPF). The primary driving mode applied in this study was accelerating mode. However, regarding the particle emissions also a constant speed mode was analysed. The investigated CNG buses emitted on average a higher number of particles but less mass compared to the diesel-fuelled buses. Emission factors for number of particles (EFPN) were EFPN, DPF = 4.4 ± 3.5 × 1014, EFPN, no DPF = 2.1 ± 1.0 × 1015 and EFPN, CNG = 7.8 ± 5.7 ×1015 kg fuel-1. In the accelerating mode, size-resolved emission factors (EFs) showed unimodal number size distributions with peak diameters of 70-90 nm and 10 nm for diesel and CNG buses, respectively. For the constant speed mode, bimodal average number size distributions were obtained for the diesel buses with peak modes of ~10 nm and ~60 nm. Emission factors for NOx expressed as NO2 equivalents for the diesel buses were on average 27 ± 7 g (kg fuel)-1 and for the CNG buses 41 ± 26 g (kg fuel)-1. An anti-relationship between EFNOx and EFPM was observed especially for buses with no DPF, and there was a positive relationship between EFPM and EFCO.

Maryland motor carrier program performance enhancement : [research summary].

DOT National Transportation Integrated Search

2014-02-01

The Maryland Motor Carrier Program (MMCP) involves the regulation of : commercial vehicle safety inspections. This includes roadside inspections : programs which have a goal of improving safety and reducing crashes : involving commercial vehicles. Th...

The NASA-USPHS Health Evaluation and Enhancement Program

NASA Technical Reports Server (NTRS)

Durbeck, D. C.; Heinzelmann, F.; Moxley, R. T., III; Schacther, J.; Payne, G. H.; Limoncelli, D. D.; Fox, S. M., III; Arnoldi, L. B.

1972-01-01

An exercise program was initiated to assess the feasibility of an on the job health evaluation and enhancement program, as well as to identify the factors which influenced volunteering, adherence, and effectiveness of the program. The program was utilized by 237 of the 998 eligible Federal employees, with a mean attendance of 1.3 days per week. Those who volunteered perceived a need for increased physical activity, felt they had sufficient time to participate, and derived subjective as well as objective benefits. Significant improvements were found in heart rate response to the standard exercise test, body weight, skinfold measurements, and triglycerides. A consistent relationship was found between subjectively reported effects of the program on work, health habits, and behavior, and improvement in cardiovascular function, based on treadmill performance. Numerous personal and programmatic factors influencing volunteering and participation were identified.

MLS student active learning within a "cloud" technology program.

PubMed

Tille, Patricia M; Hall, Heather

2011-01-01

In November 2009, the MLS program in a large public university serving a geographically large, sparsely populated state instituted an initiative for the integration of technology enhanced teaching and learning within the curriculum. This paper is intended to provide an introduction to the system requirements and sample instructional exercises used to create an active learning technology-based classroom. Discussion includes the following: 1.) define active learning and the essential components, 2.) summarize teaching methods, technology and exercises utilized within a "cloud" technology program, 3.) describe a "cloud" enhanced classroom and programming 4.) identify active learning tools and exercises that can be implemented into laboratory science programs, and 5.) describe the evaluation and assessment of curriculum changes and student outcomes. The integration of technology in the MLS program is a continual process and is intended to provide student-driven active learning experiences.

The enhancement of adaptation and psychological well-being among victims of flooding and landslide in Thailand.

PubMed

Oba, Nongnut; Suntayakorn, Chanjar; Sangkaewsri, Roongsri; Longchupol, Chaowanee; Lohitpintu, Itsareat; Kumsri, Tongbai

2010-03-01

To explore the needs of potential enhancement for adaptation and to examine the effectiveness of the potential enhancement program for adaptation and psychological well-being among victims of flooding and landslide in Lublae district Uttaradit Province, Thailand. 3 step of research and development; the needs of potential enhancement for adaptation among victims of flooding and landslide were analyzed by focus group discussion, the potential enhancement program (PEP) was designed by brainstorming of three groups of stakeholder; victims, health volunteers and health personnel and the effectiveness of PEP was tested by the difference of adaptation and psychological well-being perception among victims of flooding and landslide between before and after intervention. Thumbun Maepou, Lublae district, Uttaradit Province, Thailand. The needs of potential enhancement among victims of flooding and landslide were set up warning network along the risk canal and mountain, first aid training for health volunteer, and program of psychological health promotion. The PEP composed of community flooding and landslide rehearsal training, health education and dissemination and knowledge management. Total adaptation and psychological wellbeing of samples after intervention were significantly higher than that of before intervention at 0.05 and 0.001, respectively. The restoration of adaptation and psychological well-being among victims of flooding and landslide were essential to maintained holistic health.

Human Memory Organization for Computer Programs.

ERIC Educational Resources Information Center

Norcio, A. F.; Kerst, Stephen M.

1983-01-01

Results of study investigating human memory organization in processing of computer programming languages indicate that algorithmic logic segments form a cognitive organizational structure in memory for programs. Statement indentation and internal program documentation did not enhance organizational process of recall of statements in five Fortran…

Here's How to Keep Your Music Program Humming.

ERIC Educational Resources Information Center

McCormick, Kathleen

1985-01-01

Some school systems are finding practical ways to enhance music programs. Experts suggest ways for schools to (1) build a marketing plan, (2) make it easier for children to participate in the music program, (3) provide reinforcement, and (4) publicize the program. (MLF)

Project Parents: Awareness, Education, Involvement Program. O.E.E. Evaluation Report, 1981-1982.

ERIC Educational Resources Information Center

Lehman, Sheila; Frischholz, Edward J.

The Project Parents: Awareness, Education, Involvement Program is an educational program which is conducted by the New York City Schools and involves 144 parents with children in elementary level bilingual education programs or eligible for such programs. While the focus of the program is on parents, its goal is the enhanced educational…

34 CFR 611.41 - Under what circumstances may an individual receive a scholarship of program funds to attend a...

Code of Federal Regulations, 2013 CFR

2013-07-01

... scholarship of program funds to attend a teacher training program? 611.41 Section 611.41 Education Regulations..., DEPARTMENT OF EDUCATION TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM Scholarships § 611.41 Under what circumstances may an individual receive a scholarship of program funds to attend a teacher training program? (a...

34 CFR 611.41 - Under what circumstances may an individual receive a scholarship of program funds to attend a...

Code of Federal Regulations, 2012 CFR

2012-07-01

... scholarship of program funds to attend a teacher training program? 611.41 Section 611.41 Education Regulations..., DEPARTMENT OF EDUCATION TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM Scholarships § 611.41 Under what circumstances may an individual receive a scholarship of program funds to attend a teacher training program? (a...

34 CFR 611.41 - Under what circumstances may an individual receive a scholarship of program funds to attend a...

Code of Federal Regulations, 2014 CFR

2014-07-01

... scholarship of program funds to attend a teacher training program? 611.41 Section 611.41 Education Regulations..., DEPARTMENT OF EDUCATION TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM Scholarships § 611.41 Under what circumstances may an individual receive a scholarship of program funds to attend a teacher training program? (a...

A school-based, peer leadership physical activity intervention for 6th graders: feasibility and results of a pilot study.

PubMed

Barr-Anderson, Daheia J; Laska, Melissa N; Veblen-Mortenson, Sara; Farbakhsh, Kian; Dudovitz, Bonnie; Story, Mary

2012-05-01

The aim of this study was to promote physical activity in 6th graders by developing and testing the feasibility of an enhanced Presidential Active Lifestyle Award (PALA) program comprised of a peer leadership component and innovative exercise resource toolkit including DVDs. A racially/ethnically diverse sample of students received the standard PALA program (2 control schools, n = 61) or enhanced PALA+Peers program (2 intervention schools, n = 87) during 2006-2007 academic year. Compared with the control condition, the intervention was successful in increasing moderate physical activity in all students (P = .02) and moderate and hard physical activity among girls (P = .03 and P = .04, respectively). Teachers and students reported a high level of satisfaction and receptivity with the intervention. All teachers thought the DVDs were well-received, and 87% of students reported that they would recommend the enhanced program to peers. Coupling peer leadership and DVDs that promote physical activity may be an effective way to increase youth physical activity.

Health economics and outcomes research fellowship practices reviewed.

PubMed

Suh, Kangho; Gabriel, Susan; Adams, Michelle A; Arcona, Steve

2015-01-01

The guidelines for health economics and outcomes research (HEOR) fellowship training programs devised by the American College of Clinical Pharmacy (ACCP) and the International Society of Pharmacoeconomics and Outcomes Research (ISPOR) suggest that continuous improvements are made to ensure that postgraduate training through didactic and professional experiences prepare fellows for HEOR research careers. The HEOR Fellowship Program at Novartis Pharmaceuticals Corporation was standardized to enhance the fellows' HEOR research understanding and align professional skill sets with the ACCP-ISPOR Fellowship Program Guidelines. Based on feedback from an internal task force comprised of HEOR employees and current and former fellows, the HEOR Fellowship Program was normatively and qualitatively assessed to evaluate the current curricular program. Fellowship program activities were instituted to ensure that the suggested minimum level requirements established by the guidelines were being met. Research opportunities enabling fellows to work hand-in-hand with other fellows and HEOR professionals were emphasized. Curricular enhancements in research methodology and professional training and development, and materials for a structured journal club focusing on specific methodological and HEOR research topics were developed. A seminar series (e.g., creating SMART Goals, StrengthsFinder 2.0) and professional courses (e.g., ISPOR short courses, statistics.com) were included to enhance the fellows' short- and long-term professional experience. Additional program attributes include an online reference library developed to enrich the current research facilities and a Statistical Analysis Software training program. Continuously assessing and updating HEOR fellowship programs keeps programs up-to-date in the latest HEOR concepts and approaches used to evaluate health care, both professionally and educationally. Copyright © 2015 Elsevier Inc. All rights reserved.

San Pablo Bay Tidal Marsh Enhancement and Water Quality Improvement Project

EPA Pesticide Factsheets

Information about the SFBWQP San Pablo Bay Tidal Marsh Enhancement and Water Quality Improvement Project, part of an EPA competitive grant program to improve SF Bay water quality focused on restoring impaired waters and enhancing aquatic resources.

Can Co-Curricular Activities Enhance the Learning Effectiveness of Students?: An Application to the Sub-Degree Students in Hong Kong

ERIC Educational Resources Information Center

Leung, Chi-Hung; Ng, Chi Wing Raymond; Chan, Po On Ella

2011-01-01

A total of 575 students from the Associate Degree Foundation Program and the Associate Degree Program participated in this study. The two purposes of this study were to use the time series between/within experimental design to examine whether participation in co-curricular activities could (1) enhance student learning effectiveness and (2) have…

Enhancing and Well-Being of Young Children and Families in the Context of Welfare Reform: Lessons from Early Childhood, TANF, and Family Support Programs.

ERIC Educational Resources Information Center

Knitzer, Jane; Cauthen, Nancy K.

This report presents findings about emerging approaches to enhance the well-being of young children and families in the context of welfare reform. Information on programs and initiatives was obtained from nomination forms sent to over 300 key informants, including child care officials, Head Start collaboration directors, governors' early childhood…

Public attitudes toward programs designed to enhance forest related benefits on private lands

Treesearch

Donald F. Dennis; Mark J. Twery; Michael A. Rechlin; Bruce Hansen

2003-01-01

Public agencies may at times provide education, technical help, tax incentives, or other forms of aid to private landowners to help them enhance their land in ways that benefit the public. Since public funds are used to pay these expenses, it is important that program goals be correlated with underlying public values and concerns. We used a conjoint ranking survey to...

Enhancing Cognitive and Social-Emotional Development through a Simple-to-Administer Mindfulness-Based School Program for Elementary School Children: A Randomized Controlled Trial

ERIC Educational Resources Information Center

Schonert-Reichl, Kimberly A.; Oberle, Eva; Lawlor, Molly Stewart; Abbott, David; Thomson, Kimberly; Oberlander, Tim F.; Diamond, Adele

2015-01-01

The authors hypothesized that a social and emotional learning (SEL) program involving mindfulness and caring for others, designed for elementary school students, would enhance cognitive control, reduce stress, promote well-being and prosociality, and produce positive school outcomes. To test this hypothesis, 4 classes of combined 4th and 5th…

A Pilot Study of the Feasibility and Efficacy of the Strategies to Enhance Positive Parenting (STEPP) Program for Single Mothers of Children with ADHD

ERIC Educational Resources Information Center

Chacko, Anil; Wymbs, Brian T.; Flammer-Rivera, Lizette M.; Pelham, William E.; Walker, Kathryn S.; Arnold, Fran W.; Visweswaraiah, Hema; Swanger-Gagne, Michelle; Girio, Erin L.; Pirvics, Lauma L.; Herbst, Laura

2008-01-01

Objective: The Strategies to Enhance Positive Parenting (STEPP) program was developed to address putative factors related to poor engagement in and outcomes following traditional behavioral parent training (BPT) for single mothers of children diagnosed with ADHD. Method: Twelve single mothers of children with ADHD were enrolled in an initial…

Enhancements and Algorithms for Avionic Information Processing System Design Methodology.

DTIC Science & Technology

1982-06-16

programming algorithm is enhanced by incorporating task precedence constraints and hardware failures. Stochastic network methods are used to analyze...allocations in the presence of random fluctuations. Graph theoretic methods are used to analyze hardware designs, and new designs are constructed with...There, spatial dynamic programming (SDP) was used to solve a static, deterministic software allocation problem. Under the current contract the SDP

Intervening in the Professional Development of Science Teachers: The Colorado Science Teaching Enhancement Program. Interim Report of the Formative Evaluation of CO-STEP.

ERIC Educational Resources Information Center

Ellis, James D.; Maxwell, Donald E.

The purposes of the Colorado Science Teaching Enhancement Program (CO-STEP) are to improve the background in science content and the instructional skills of teachers in grades four through six throughout Colorado and to support the implementation of effective instruction. A network of six Teacher Development Centers in Colorado coordinate teacher…

Combating Terrorism: U.S. Efforts in Northwest Africa Would Be Strengthened by Enhanced Program Management

DTIC Science & Technology

2014-06-01

activities in 11 countries—Algeria, Burkina Faso, Cameroon, Chad, Mali, Mauritania, Morocco , Niger, Nigeria, Senegal, and Tunisia...are typically State-implemented and are used to support activities designed to enhance the law enforcement capacity and antiterrorism skills of...for other anticrime purposes. INCLE funds are typically State- implemented and are used to develop and implement policies and programs that maintain

Troubleshooting Assessment and Enhancement (TAE) Program: Test and Evaluation

DTIC Science & Technology

1991-04-01

Navy Personnel Research and Development Center San Diego, California 92152-6800 TN-91-13 April 1991 AD-A23 6 323 Troubleshooting Assessment and...00002 NPRDC-TN-91-13 April 1991 Troubleshooting Assessment and Enhancement (TAE) Program: Test and Evaluation Harry B. Conner Navy Personnel Research ...McLachlan Director, Training Systems Department Approved for public release; distribution is unlimited. Navy Personnel Research and Development Center

Students' Perceptions of Group Journal Writing as a Tool for Enhancing Sense of Community on Wilderness Educational Expeditions

ERIC Educational Resources Information Center

Asfeldt, Morten; Purc-Stephenson, Rebecca; Hvenegaard, Glen

2017-01-01

Journal writing is a common practice in outdoor education (OE) and there is a long-standing claim that OE programs enhance sense of community (SOC). However, there remains a call for additional evidence to support the relationship between participation in outdoor programs and SOC. This study examines students' perceptions of the role of a group…

75 FR 22767 - National Institute on Disability and Rehabilitation Research (NIDRR)-Disability and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-30

... vocational rehabilitation (VR) programs, or other programs serving transition-age youth with disabilities. (b...) Enhancement of the knowledge base of policy makers, State VR personnel, and personnel of other programs...

Therapeutic Uses of Outdoor Education. ERIC Digest.

ERIC Educational Resources Information Center

Berman, Dene S.; Davis-Berman, Jennifer

This digest examines the positive effects on emotional well-being of several types of outdoor education programs. Although many outdoor education and experiential programs enhance emotional growth, such "therapeutic" outcomes may be considered incidental to program goals. In contrast, programs aimed primarily at "therapy"…

76 FR 7175 - Native Hawaiian Education Program; Office of Elementary and Secondary Education; Overview...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-09

... DEPARTMENT OF EDUCATION Native Hawaiian Education Program; Office of Elementary and Secondary Education; Overview Information; Native Hawaiian Education Program; Notice Inviting Applications for New... Hawaiian Education (NHE) program is to support innovative projects that enhance the educational services...

7 CFR 1493.470 - Evidence of export.

Code of Federal Regulations, 2012 CFR

2012-01-01

... OF AGRICULTURE EXPORT PROGRAMS CCC EXPORT CREDIT GUARANTEE PROGRAMS CCC Supplier Credit Guarantee... provide CCC an evidence of export report for each shipment made under the payment guarantee. This report... participation in any of the following CCC or USDA export program: Export Enhancement Program, Dairy Export...

7 CFR 1493.470 - Evidence of export.

Code of Federal Regulations, 2014 CFR

2014-01-01

... OF AGRICULTURE EXPORT PROGRAMS CCC EXPORT CREDIT GUARANTEE PROGRAMS CCC Supplier Credit Guarantee... provide CCC an evidence of export report for each shipment made under the payment guarantee. This report... participation in any of the following CCC or USDA export program: Export Enhancement Program, Dairy Export...

7 CFR 1493.470 - Evidence of export.

Code of Federal Regulations, 2013 CFR

2013-01-01

... OF AGRICULTURE EXPORT PROGRAMS CCC EXPORT CREDIT GUARANTEE PROGRAMS CCC Supplier Credit Guarantee... provide CCC an evidence of export report for each shipment made under the payment guarantee. This report... participation in any of the following CCC or USDA export program: Export Enhancement Program, Dairy Export...

Quantitative and Qualitative Evaluations of the Enhanced Logo-autobiography Program for Korean-American Women.

PubMed

Sung, Kyung Mi; Bernstein, Kunsook

2017-12-01

This study extends Bernstein et al.'s (2016) investigation of the effects of the Enhanced Logo-autobiography Program on Korean-American women's depressive symptoms, coping strategies, purpose in life, and posttraumatic growth by analyzing quantitative and qualitative data. This study's participants significantly improved on quantitative measures of depression, coping strategies, purpose in life, and post-traumatic growth at eight weeks post-intervention and follow-up. The qualitative content analysis revealed 17 themes with five essential themes. The program's activity to promote purpose in life through posttraumatic growth facilitated participants' recovery from traumatic experiences. Standardized guidelines are needed to conduct this program in Korean community centers.

78 FR 44331 - Semiannual Regulatory Agenda

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-23

... Business Mentor- 3245-AG24 Protege Programs. 254 Small Business HUBZone 3245-AG38 Program. 255 Agent... Mentor-Protege Programs Legal Authority: Pub. L. 111-240; sec 1347; 15 U.S.C. 657r Abstract: SBA currently has a mentor-protege program for the 8(a) Business Development Program that is intended to enhance...

Enhancing the Attractiveness of Alcohol Education Via a Microcomputer Program.

ERIC Educational Resources Information Center

Meier, Scott T.

Getting students' attention is one of the most difficult problems for counselors who conduct alcohol education programs in high schools or colleges. A computer-aided instruction program using microcomputers for alcohol education was developed entitled "If You Drink: An Alcohol Education Program" (IYD). The IYD program consists of five modules: the…

78 FR 79253 - CCC Export Credit Guarantee (GSM-102) Program and Facility Guarantee Program (FGP)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-27

... increase program availability to all program participants and enhance access and encourage sales for... through the repayment period; and (3) program fees are too high. This respondent also commented that the country risk classification for South Korea is too high (i.e., risky), and questioned whether the purpose...

Influence of financial incentive programs in sustaining wildlife values

Treesearch

Thomas J. Straka; Michael A. Kilgore; Michael G. Jacobson; John L. Greene; Steven E. Daniels

2007-01-01

Conservation incentive programs have substantial impacts on the nation’s forests and wildlife habitat. There are eight major conservation incentive programs. The Forest Stewardship Program (FSP) provides forest landowner assistance by focusing on resource management plans embodying multi-resource stewardship principles. The Forest Land Enhancement Program (FLEP) is the...

Evaluating Effectiveness of Pair Programming as a Teaching Tool in Programming Courses

ERIC Educational Resources Information Center

Faja, Silvana

2014-01-01

This study investigates the effectiveness of pair programming on student learning and satisfaction in introductory programming courses. Pair programming, used in the industry as a practice of an agile development method, can be adopted in classroom settings to encourage peer learning, increase students' social skills, and enhance student…

Effectiveness of Program Visualization: A Case Study with the ViLLE Tool

ERIC Educational Resources Information Center

Rajala, Teemu; Laakso, Mikko-Jussi; Kaila, Erkki; Salakoski, Tapio

2008-01-01

Program visualization is one of the various methods developed over the years to aid novices with their difficulties in learning to program. It consists of different graphical--often animated--and textual objects, visualizing the execution of programs. The aim of program visualization is to enhance students' understanding of different areas of…

Using the lessons of behavioral economics to design more effective pay-for-performance programs.

PubMed

Mehrotra, Ateev; Sorbero, Melony E S; Damberg, Cheryl L

2010-07-01

To describe improvements in the design of pay-for-performance (P4P) programs that reflect the psychology of how people respond to incentives. Investigation of the behavioral economics literature. We describe 7 ways to improve P4P program design in terms of frequency and types of incentive payments. After discussing why P4P incentives can have unintended adverse consequences, we outline potential ways to mitigate these. Although P4P incentives are increasingly popular, the healthcare literature shows that these have had minimal effect. Design improvements in P4P programs can enhance their effectiveness. Lessons from behavioral economics may greatly enhance the design and effectiveness of P4P programs in healthcare, but future work is needed to demonstrate this empirically.

Using a systems orientation and foundational theory to enhance theory-driven human service program evaluations.

PubMed

Wasserman, Deborah L

2010-05-01

This paper offers a framework for using a systems orientation and "foundational theory" to enhance theory-driven evaluations and logic models. The framework guides the process of identifying and explaining operative relationships and perspectives within human service program systems. Self-Determination Theory exemplifies how a foundational theory can be used to support the framework in a wide range of program evaluations. Two examples illustrate how applications of the framework have improved the evaluators' abilities to observe and explain program effect. In both exemplars improvements involved addressing and organizing into a single logic model heretofore seemingly disparate evaluation issues regarding valuing (by whose values); the role of organizational and program context; and evaluation anxiety and utilization. Copyright 2009 Elsevier Ltd. All rights reserved.

[Effect of nasal CPAP on human diaphragm position and lung volume].

PubMed

Yoshimura, N; Abe, T; Kusuhara, N; Tomita, T

1994-11-01

The cephalic margin of the zone of apposition (ZOA) was observed with ultrasonography at ambient pressure and during nasal continuous positive airway pressure (nasal CPAP) in nine awake healthy males in a supine position. In a relaxed state at ambient pressure, there was a significant (p < 0.001) linear relationship between lung volume and the movement of the cephalic margin of the ZOA over the range from maximum expiratory position (MEP) to maximum inspiratory position (MIP). With nasal CPAP, functional residual capacity increased significantly (p < 0.01) in proportion to the increase in CPAP. At 20 cmH2O CPAP, the mean increase in volume at end expiration was 36% of the vital capacity measured at ambient pressure. The cephalic margin of the ZOA moved significantly (p < 0.01) in a caudal direction as CPAP was increased. At 20 cmH2O CPAP, the cephalic margin of the ZOA at end expiratory position (EEP) had moved 55% of the difference from MIP to MEP measured at ambient pressure. The end expiratory diaphragm position during nasal CPAP was lower than the diaphragm position at ambient pressure when lung volumes were equal. These results suggest that during nasal CPAP the chest wall is distorted from its relaxed configuration, with a decrease in rib cage expansion and an increase in outward displacement of the abdominal wall.

Chemical Characteristics of Particulate Matter from Vehicle emission using High Resolution Time of Flight Aerosol Mass Spectrometer (HR-ToF-AMS)

NASA Astrophysics Data System (ADS)

Park, T.; Lee, T.; Kang, S.; Lee, J.; Kim, J.; Son, J.; Yoo, H. M.; Kim, K.; Park, G.

2015-12-01

Car emissions are major contributors of particulate matter (PM) in the urban environment and effects of air pollution, climate change, and human activities. By increasing of interest in research of car emission for assessment of the PM control, it became require to understand the chemical composition and characteristics of the car exhaust gases and particulate matter. To understand car emission characteristics of PM, we will study PM of car emissions for five driving modes (National Institute Environmental Research (NIER)-5, NIER-9, NIER-12, NIER-14) and three fixed speed driving modes (30km/h, 70km/h, 110km/h) using different fuel types (gasoline, diesel, and LPG) at Transportation Pollution Research Center (TPRC) of NIER in Incheon, South Korea. PM chemical composition of car emission was measured for concentrations of organics, sulfate, nitrate, ammonium, PAHs, oxidation states and size distribution using an Aerodyne High Resolution Time-of-Flight Aerosol Mass Spectrometer (HR-ToF-AMS) and engine exhaust particle sizer (EEPS) on real-time. In the study, organics concentration was dominated for all cases of driving modes and the concentration of organics was increased in 110km/h fixed speed mode for gasoline and diesel. The presentation will provide an overview of the chemical composition of PM in the car emissions.

An Integrated Age Model for the Cocos Plate using IODP CRISP Drilling Data

NASA Astrophysics Data System (ADS)

Baxter, A. T.; Kutterolf, S.; Schindlbeck, J. C.; Sandoval, M. I.; Barckhausen, U.; Li, Y. X.; Petronotis, K. E.

2017-12-01

We present an integrated age model for the incoming Cocos Plate sediments offshore Costa Rica. The data, collected over two IODP Expeditions (334 and 344), provides a medium- to high-resolution record from the initial formation of the ocean crust in the Miocene to the present day. This study provides >50 age control points for the CRISP sediments from Sites U1381 and U1414. Although the two sites are just 10 km apart, there are distinct differences in the sediment and tephra record. Most notable is the presence of a hiatus at Site U1381. The hiatus, which is seen at other sites on the Cocos Plate, but not at Site U1414, may be related to erosion due to bottom water currents, mass wasting from Cocos Ridge subduction or may be related to the closure of the Central American Seaway (CAS). Sediment accumulation rates in the Miocene are comparable to modern abyssal plain rates. However, an increase is observed in the Pleistocene, when detritus from the forearc basin appears at Site U1414 2 Ma, shortly after the initiation of Cocos Ridge subduction. A tectonic model is presented that reconstructs the Cocos Plate, from its formation at 23 Ma to the present day. Eastern Equatorial Pacific (EEP) paleoceanographic events, such as the Miocene `carbonate crash' and the Late Miocene-Early Pliocene `biogenic bloom' observed at Site U1414, are also discussed.

[Frontal symptoms, self-perceived stress, and subjective memory complaints in substance abusers].

PubMed

Terán-Mendoza, Oscar; Sira-Ramos, Diayanny; Guerrero-Alcedo, Jesús; Arroyo-Alvarado, Daniela

2016-04-01

Substance addiction is a public health problem considering that every day increases the number of individuals with problem drug use, in this sense it is interesting the study of neuropsychological variables to understand the nature of addiction, understanding that brain circuits are involved in the establishment, maintenance and rehabilitation of the same. To determine the influence of addiction on the frontal symptoms, self-perceived stress and subjective memory complaints, secondly, to analyze how these variables relate to people with addictions and finally, establish differences in them between addicts with and without subjective memory complaints. ISP, EEP-14 and MFE-30 instruments were applied to a sample of 115 substance abusers, and 115 people from non-clinical population, matched for age, sex and educational level. Significant differences are evident between addicted to substances and non-clinical subjects in the emotional scale ISP and MFE-30, also in the clinical sample highly significant correlations between all scales are observed; Finally, among people with addictions who reported memory complaints and those who do not, significant differences are evident on all scales except for the self-perceived stress. It is considered necessary to take into account the levels of self-perceived stress, frontal symptoms and subjective memory complaints in substance abusers, because the executive, attentional and mnemonic problems may affect several variables in the process of treatment and rehabilitation.

Coincidence (e,e'p) Scattering on 40Ar and 48Ti to Aid Precision Neutrino Oscillation Experiments

NASA Astrophysics Data System (ADS)

Abrams, Dan; E12-14-012 Collaboration

2017-09-01

Neutrino oscillations are an active area of research, with experiments such as DUNE (Deep Underground Neutrino Experiment). DUNE will make use of large liquid argon detectors to perform a precision measurement of the CP violating phase. Hence, an understanding of the argon nuclear ground state and its response to (anti-)neutrino interactions is of paramount importance. Information about the nuclear ground state is encapsulated in the spectral function, S (k , E) , the joint probability of removing a nucleon of momentum k = |k | from the ground state leaving the residual (A-1) system with excitation energy E. E12-14-012 at Jefferson Lab ran in early 2017 and has measured the argon spectral function through coincidence (e ,e' p) scattering on 40Ar and 48Ti. The results of E12-14-012 are important to both the neutrino and nuclear physics communities. A direct measurement of the coincidence (e ,e' p) cross section from 40Ar and 48Ti will provide valuable information about the argon nucleus, as well as the experimental input necessary to constrain theoretical models used to calculate S (k , E) , paving the way for reliable estimates of the neutrino cross sections. Data from E12-14-012 is currently being analyzed at UVA and Va. Tech. Supported in part by the Department of Energy Grant No: DE-FG02-96ER40950.

K-12 Neuroscience Education Outreach Program: Interactive Activities for Educating Students about Neuroscience.

PubMed

Deal, Alex L; Erickson, Kristen J; Bilsky, Edward J; Hillman, Susan J; Burman, Michael A

2014-01-01

The University of New England's Center for Excellence in the Neurosciences has developed a successful and growing K-12 outreach program that incorporates undergraduate and graduate/professional students. The program has several goals, including raising awareness about fundamental issues in neuroscience, supplementing science education in area schools and enhancing undergraduate and graduate/professional students' academic knowledge and skill set. The outreach curriculum is centered on core neuroscience themes including: Brain Safety, Neuroanatomy, Drugs of Abuse and Addiction, Neurological and Psychiatric Disorders, and Cognition and Brain Function. For each theme, lesson plans were developed based upon interactive, small-group activities. Additionally, we've organized our themes in a "Grow-up, Grow-out" approach. Grow-up refers to returning to a common theme, increasing in complexity as we revisit students from early elementary through high school. Grow-out refers to integrating other scientific fields into our lessons, such as the chemistry of addiction, the physics of brain injury and neuronal imaging. One of the more successful components of our program is our innovative team-based model of curriculum design. By creating a team of undergraduate, graduate/professional students and faculty, we create a unique multi-level mentoring opportunity that appears to be successful in enhancing undergraduate students' skills and knowledge. Preliminary assessments suggest that undergraduates believe they are enhancing their content knowledge and professional skills through our program. Additionally, we're having a significant, short-term impact on K-12 interest in science. Overall, our program appears to be enhancing the academic experience of our undergraduates and exciting K-12 students about the brain and science in general.

Medicare program; prohibition of midyear benefit enhancements for Medicare Advantage organizations. Final rule.

PubMed

2008-07-28

This final rule prohibits Medicare Advantage (MA) organizations, including organizations offering MA plans to employer and union group health plan sponsors, from making midyear changes to nonprescription drug benefits, premiums, and cost-sharing submitted in their approved bids for a given contract year. This final rule also clarifies that MA organizations offering certain kinds of plans restricted to employer and union group health plan sponsors and not open to general enrollment may continue to offer benefit enhancements as they do currently, through means other than midyear benefit enhancements (MYBEs). Programs of all-inclusive care for elderly (PACE) are not subject to the provisions of this final rule and may continue to offer enhanced benefits as specified in our guidance for PACE plans.

Addressing Literacy and Numeracy to Improve Diabetes Care

PubMed Central

Cavanaugh, Kerri; Wallston, Kenneth A.; Gebretsadik, Tebeb; Shintani, Ayumi; Huizinga, Mary Margaret; Davis, Dianne; Gregory, Rebecca Pratt; Malone, Robb; Pignone, Michael; DeWalt, Darren; Elasy, Tom A.; Rothman, Russell L.

2009-01-01

OBJECTIVE Diabetic patients with lower literacy or numeracy skills are at greater risk for poor diabetes outcomes. This study evaluated the impact of providing literacy- and numeracy-sensitive diabetes care within an enhanced diabetes care program on A1C and other diabetes outcomes. RESEARCH DESIGN AND METHODS In two randomized controlled trials, we enrolled 198 adult diabetic patients with most recent A1C ≥7.0%, referred for participation in an enhanced diabetes care program. For 3 months, control patients received care from existing enhanced diabetes care programs, whereas intervention patients received enhanced programs that also addressed literacy and numeracy at each institution. Intervention providers received health communication training and used the interactive Diabetes Literacy and Numeracy Education Toolkit with patients. A1C was measured at 3 and 6 months follow-up. Secondary outcomes included self-efficacy, self-management behaviors, and treatment satisfaction. RESULTS At 3 months, both intervention and control patients had significant improvements in A1C from baseline (intervention −1.50 [95% CI −1.80 to −1.02]; control −0.80 [−1.10 to −0.30]). In adjusted analysis, there was greater improvement in A1C in the intervention group than in the control group (P = 0.03). At 6 months, there were no differences in A1C between intervention and control groups. Self-efficacy improved from baseline for both groups. No significant differences were found for self-management behaviors or satisfaction. CONCLUSIONS A literacy- and numeracy-focused diabetes care program modestly improved self-efficacy and glycemic control compared with standard enhanced diabetes care, but the difference attenuated after conclusion of the intervention. PMID:19741187

Enhancing Drug Court Success

ERIC Educational Resources Information Center

Deschenes, Elizabeth Piper; Ireland, Connie; Kleinpeter, Christine B.

2009-01-01

This study evaluates the impact of enhanced drug court services in a large county in Southern California. These enhanced services, including specialty counseling groups, educational/employment resources, and increased Residential Treatment (RT) beds, were designed to increase program retention and successful completion (graduation) of drug court.…

Enhancing Social Responsibility and Prosocial Leadership to Prevent Aggression, Peer Victimization, and Emotional Problems in Elementary School Children.

PubMed

Leadbeater, Bonnie J; Thompson, Kara; Sukhawathanakul, Paweena

2016-12-01

Testing the theories that form the basis of prevention programs can enhance our understanding of behavioral change and inform the development, coordination, and adaptation of prevention programs. However, theories of change showing the linkages from intervention program components to risk or protective factors to desired outcomes across time are rarely specified or tested. In this 2-year longitudinal study, we test the theory that increases in two protective factors (i.e., children's prosocial leadership and their teachers' expectations of social responsibility) targeted by the WITS Programs (Walk Away, Ignore, Talk it Out, and Seek Help) would be associated with declines in peer victimization, aggression, and emotional problems. Participants included Canadian students, in grades 1-4 at baseline (n = 1329) and their parents and teachers. Consistent with our theory of change, variability in program implementation (adherence and integration) and in children's use of program skills (child responsiveness) are related to increases in both protective factors. Increases in these protective factors are associated with subsequent declines in children's aggression, victimization, and emotional problems. We discuss how enhancement of these protective factors may operate to improve child outcomes and the need for theory-based research to refine and improve the effectiveness of intervention strategies and to improve program scale-up. © Society for Community Research and Action 2016.

Graphics and composite material computer program enhancements for SPAR

NASA Technical Reports Server (NTRS)

Farley, G. L.; Baker, D. J.

1980-01-01

User documentation is provided for additional computer programs developed for use in conjunction with SPAR. These programs plot digital data, simplify input for composite material section properties, and compute lamina stresses and strains. Sample problems are presented including execution procedures, program input, and graphical output.

75 FR 39323 - Amendment to the Biometric Visa Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-08

... DEPARTMENT OF STATE [Public Notice: 7047] Amendment to the Biometric Visa Program AGENCY: Department of State. ACTION: Notice of Amendment to the Biometric Visa Program. This public notice announces an amendment to the Biometric Visa Program. Section 303 of the Enhanced Border Security and Visa...

36 CFR 230.32 - National program administration.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false National program... AGRICULTURE STATE AND PRIVATE FORESTRY ASSISTANCE Forest Land Enhancement Program § 230.32 National program... three geographic funding areas based on the criteria set out in the Forest Service Manual Chapter 3310...

36 CFR 230.32 - National program administration.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false National program... AGRICULTURE STATE AND PRIVATE FORESTRY ASSISTANCE Forest Land Enhancement Program § 230.32 National program... three geographic funding areas based on the criteria set out in the Forest Service Manual Chapter 3310...

Impact of a colorectal enhanced recovery program implementation on clinical outcomes and institutional costs: A prospective cohort study with retrospective control.

PubMed

Portinari, Mattia; Ascanelli, Simona; Targa, Simone; Dos Santos Valgode, Elisabete Maria; Bonvento, Barbara; Vagnoni, Emidia; Camerani, Stefano; Verri, Marco; Volta, Carlo Alberto; Feo, Carlo V

2018-05-01

The enhanced recovery program for perioperative care of the surgical patient reduces postoperative metabolic response and organ dysfunction, accelerating functional recovery. The aim of this study was to determine the impact on postoperative recovery and cost-effectiveness of implementing a colorectal enhanced recovery program in an Italian academic centre. A prospective series of consecutive patients (N = 100) undergoing elective colorectal resection completing a standardized enhanced recovery program in 2013-2015 (ERP group) was compared to patients (N = 100) operated at the same institution in 2010-2011 (Pre-ERP group) before introducing the program. The exclusion criteria were: >80 years old, ASA score of IV, a stage IV TNM, and diagnosis of inflammatory bowel disease. The primary outcome was hospital length of stay which was used as a proxy of functional recovery. Secondary outcomes included: postoperative complications, 30-day readmission and mortality, protocol adherence, nursing workload, cost-effectiveness, and factors predicting prolonged hospital stay. The ERP group patient satisfaction was also evaluated. Hospital stay was significantly reduced in the ERP versus the Pre-ERP group (4 versus 8 days) as well as nursing workload, with no increase in postoperative complications, 30-day readmission or mortality. ERP group protocol adherence (81%) and patient satisfaction were high. Conventional perioperative protocol was the only independent predictor of prolonged hospital stay. Total mean direct costs per patient were significantly higher in the Pre-ERP versus the ERP group (6796.76 versus 5339.05 euros). Implementing a colorectal enhanced recovery program is feasible, efficient for functional recovery and hospital stay reduction, safe, and cost-effective. High patient satisfaction and nursing workload reduction may also be expected, but high protocol adherence is necessary. Copyright © 2018 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.