Laboratory Directed Research and Development Program FY 2006

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hansen

2007-03-08

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operatemore » unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness.« less

Laboratory directed research and development program FY 1999

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hansen, Todd; Levy, Karin

2000-03-08

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operatemore » unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. This is the annual report on Laboratory Directed Research and Development (LDRD) program for FY99.« less

Preface for the special issue of Mathematical Biosciences and Engineering, BIOCOMP 2012.

PubMed

Buonocore, Aniello; Di Crescenzo, Antonio; Hastings, Alan

2014-04-01

The International Conference "BIOCOMP2012 - Mathematical Modeling and Computational Topics in Biosciences'', was held in Vietri sul Mare (Italy), June 4-8, 2012. It was dedicated to the Memory of Professor Luigi M. Ricciardi (1942-2011), who was a visionary and tireless promoter of the 3 previous editions of the BIOCOMP conference series. We thought that the best way to honor his memory was to continue the BIOCOMP program. Over the years, this conference promoted scientific activities related to his wide interests and scientific expertise, which ranged in various areas of applications of mathematics, probability and statistics to biosciences and cybernetics, also with emphasis on computational problems. We are pleased that many of his friends and colleagues, as well as many other scientists, were attracted by the goals of this recent event and offered to contribute to its success.

KDE Bioscience: platform for bioinformatics analysis workflows.

PubMed

Lu, Qiang; Hao, Pei; Curcin, Vasa; He, Weizhong; Li, Yuan-Yuan; Luo, Qing-Ming; Guo, Yi-Ke; Li, Yi-Xue

2006-08-01

Bioinformatics is a dynamic research area in which a large number of algorithms and programs have been developed rapidly and independently without much consideration so far of the need for standardization. The lack of such common standards combined with unfriendly interfaces make it difficult for biologists to learn how to use these tools and to translate the data formats from one to another. Consequently, the construction of an integrative bioinformatics platform to facilitate biologists' research is an urgent and challenging task. KDE Bioscience is a java-based software platform that collects a variety of bioinformatics tools and provides a workflow mechanism to integrate them. Nucleotide and protein sequences from local flat files, web sites, and relational databases can be entered, annotated, and aligned. Several home-made or 3rd-party viewers are built-in to provide visualization of annotations or alignments. KDE Bioscience can also be deployed in client-server mode where simultaneous execution of the same workflow is supported for multiple users. Moreover, workflows can be published as web pages that can be executed from a web browser. The power of KDE Bioscience comes from the integrated algorithms and data sources. With its generic workflow mechanism other novel calculations and simulations can be integrated to augment the current sequence analysis functions. Because of this flexible and extensible architecture, KDE Bioscience makes an ideal integrated informatics environment for future bioinformatics or systems biology research.

Biological Environmental Sampling Technologies Assessment

DTIC Science & Technology

2015-12-01

unlimited. 13. SUPPLEMENTARY NOTES 14. ABSTRACT: U.S. Army Edgewood Chemical Biological Center, Research and Technology Directorate, BioSensors ...format (pdf) electronic version of this report: ECBC R&T Directorate, Biosciences Division, BioSensors Branch RDCB-DRB-S ATTN: Gostomski, J

Plant Habitat Facility in the JPM

NASA Image and Video Library

2017-11-21

iss053e234714 (Nov. 21, 2017) --- Advanced Plant Habitat (APH) Facility in the Japanese Experiment Module (JEM) Pressurized Module (JPM). The Plant Habitat is a fully automated facility that provides a large, enclosed, environmentally-controlled chamber for plant bioscience research.

Development of an Interdisciplinary Undergraduate Bioengineering Program at Lehigh University

ERIC Educational Resources Information Center

Herz, Lori; Russo, M. Jean; Ou-Yang, H. Daniel; El-Aasser, Mohamed; Jagota, Anand; Tatic-Lucic, Svetlana; Ochs, John

2011-01-01

The undergraduate Bioengineering Program at Lehigh University was established as part of the university's Bioscience and Biotechnology Initiative with support from the National Science Foundation through a grant from its Division of Engineering Education and Centers (EEC). The objective here is to describe the program development and…

Registered nurses' reflections on bioscience courses during the undergraduate nursing programme: an exploratory study.

PubMed

Craft, Judy A; Hudson, Peter B; Plenderleith, Mark B; Gordon, Christopher J

2017-06-01

To explore new graduate registered nurses' reflections of bioscience courses during their nursing programme and the relationship between bioscience content and their clinical practice. Undergraduate nursing students internationally find bioscience courses challenging, which may be due to the volume of content and level of difficulty of these courses. Such challenges may be exacerbated by insufficient integration between bioscience theory and nursing clinical practice. A descriptive, cross-sectional mixed methods study was conducted. A 30-item questionnaire with five written response questions which explored recently registered nurses' reflections on bioscience courses during their nursing degree was employed. Descriptive analyses were reported for individual items. Thematic analysis of qualitative responses was grouped to reveal emerging themes. Registered nurses' (n = 22) reflections revealed that bioscience courses were a significant challenge during their undergraduate programme, and they lacked confidence explaining the biological basis of nursing. Participants would like improved knowledge of the relevant bioscience for nursing and agreed that bioscience courses should be extended into the undergraduate final year. The importance of relating bioscience content to nursing practice was elaborated extensively throughout written responses. Although registered nurses reflected that bioscience courses were difficult with large volumes of content, having more bioscience with greater relevance to nursing applications was considered important in their current clinical practice. It is suggested that bioscience academics develop greater contextual links between bioscience content and clinical practice relevant to nursing. After working as a registered nurse, there was appreciation of bioscience relevance for clinical practice, and the nurses believed they would have benefitted from more nursing-related bioscience during their undergraduate programme. Focussed integration of bioscience with clinical nursing courses should be driven by academics, nurse educators and clinical nurses to provide a biological basis for patient care to nursing students. © 2016 John Wiley & Sons Ltd.

An Introduction to Programming for Bioscientists: A Python-Based Primer

PubMed Central

Mura, Cameron

2016-01-01

Computing has revolutionized the biological sciences over the past several decades, such that virtually all contemporary research in molecular biology, biochemistry, and other biosciences utilizes computer programs. The computational advances have come on many fronts, spurred by fundamental developments in hardware, software, and algorithms. These advances have influenced, and even engendered, a phenomenal array of bioscience fields, including molecular evolution and bioinformatics; genome-, proteome-, transcriptome- and metabolome-wide experimental studies; structural genomics; and atomistic simulations of cellular-scale molecular assemblies as large as ribosomes and intact viruses. In short, much of post-genomic biology is increasingly becoming a form of computational biology. The ability to design and write computer programs is among the most indispensable skills that a modern researcher can cultivate. Python has become a popular programming language in the biosciences, largely because (i) its straightforward semantics and clean syntax make it a readily accessible first language; (ii) it is expressive and well-suited to object-oriented programming, as well as other modern paradigms; and (iii) the many available libraries and third-party toolkits extend the functionality of the core language into virtually every biological domain (sequence and structure analyses, phylogenomics, workflow management systems, etc.). This primer offers a basic introduction to coding, via Python, and it includes concrete examples and exercises to illustrate the language’s usage and capabilities; the main text culminates with a final project in structural bioinformatics. A suite of Supplemental Chapters is also provided. Starting with basic concepts, such as that of a “variable,” the Chapters methodically advance the reader to the point of writing a graphical user interface to compute the Hamming distance between two DNA sequences. PMID:27271528

An Introduction to Programming for Bioscientists: A Python-Based Primer.

PubMed

Ekmekci, Berk; McAnany, Charles E; Mura, Cameron

2016-06-01

Computing has revolutionized the biological sciences over the past several decades, such that virtually all contemporary research in molecular biology, biochemistry, and other biosciences utilizes computer programs. The computational advances have come on many fronts, spurred by fundamental developments in hardware, software, and algorithms. These advances have influenced, and even engendered, a phenomenal array of bioscience fields, including molecular evolution and bioinformatics; genome-, proteome-, transcriptome- and metabolome-wide experimental studies; structural genomics; and atomistic simulations of cellular-scale molecular assemblies as large as ribosomes and intact viruses. In short, much of post-genomic biology is increasingly becoming a form of computational biology. The ability to design and write computer programs is among the most indispensable skills that a modern researcher can cultivate. Python has become a popular programming language in the biosciences, largely because (i) its straightforward semantics and clean syntax make it a readily accessible first language; (ii) it is expressive and well-suited to object-oriented programming, as well as other modern paradigms; and (iii) the many available libraries and third-party toolkits extend the functionality of the core language into virtually every biological domain (sequence and structure analyses, phylogenomics, workflow management systems, etc.). This primer offers a basic introduction to coding, via Python, and it includes concrete examples and exercises to illustrate the language's usage and capabilities; the main text culminates with a final project in structural bioinformatics. A suite of Supplemental Chapters is also provided. Starting with basic concepts, such as that of a "variable," the Chapters methodically advance the reader to the point of writing a graphical user interface to compute the Hamming distance between two DNA sequences.

55th Annual Canadian Society for Molecular Biosciences Conference on Epigenetics and Genomic Stability. Whistler, British Columbia, Canada, 14–18 March 2012.

PubMed

Nelson, Christopher J; Ausió, Juan

2012-06-01

The 55th Annual Canadian Society for Molecular Biosciences Conference on Epigenetics and Genomic Stability in Whistler, Canada, 14-18 March 2012, brought together 31 speakers from different nationalities. The organizing committee, led by Jim Davie (Chair) at the University of Manitoba (Manitoba, Canada), consisted of several established researchers in the fields of chromatin and epigenetics from across Canada. The meeting was centered on the contribution of epigenetics to gene expression, DNA damage and repair, and the role of environmental factors. A few interesting talks on replication added some insightful information on the controversial issue of histone post-translational modifications as genuine epigenetic marks that are inherited through cell division.

Key Facts about Higher Education in Washington

ERIC Educational Resources Information Center

Washington Higher Education Coordinating Board, 2011

2011-01-01

Since its establishment in the 1860s, Washington's higher education system has evolved rapidly to meet a myriad of state needs in fields as diverse as agriculture, bioscience, chemistry, environmental sciences, engineering, medicine, law, business, computer science, and architecture. Today, higher education, like other vital state functions, faces…

40 Years of Discovery

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weinstein, B; Heller, A

2003-07-08

History is most interesting when seen through the eyes of those who lived it. In this 40th anniversary retrospective of bioscience research at Lawrence Livermore National Laboratory, we've asked 19 scientists to share their personal recollections about a major accomplishment in the program's history. We have not tried to create a comprehensive or seamless story. Rather, we've attempted to capture the perspectives of key individuals, each of whom worked on a research program that met significant milestones. We have focused particularly on programs and accomplishments that have shaped the current Biology and Biotechnology Research Program (BBRP). In addition, we havemore » included a timeline of biosciences at LLNL, a history of the directorate that appeared in the Laboratory's magazine, ''Science & Technology Review'', in 2002, and a list of bioscience-related articles that have appeared over the years in ''Science & Technology Review and its predecessor, Energy & Technology Review''. The landscape of biological science today is stunningly different from 40 years ago. When LLNL bioscience began in 1963, we knew about the structure of DNA and that it was the carrier of genetic information. However, it would be another year before scientists would understand how DNA codes for the production of proteins and more than a decade before the earliest DNA sequence would be known. It is sometimes difficult to remember that it was only 15 years ago that the polymerase chain reaction, a synthetic method to amplify pieces of DNA was developed, and that only within the last half-dozen years has sequence data for entire organisms begun to be available. In this publication, we have tried to capture some of the landmark and seminal research history: radiation effects studies, which were a major reason for founding the biological research program, and flow sorting and chromosome painting, which dramatically changed our ability to study DNA damage and enabled the creation of chromosome-specific clone libraries, a key step toward sequencing the human genome. Several histories relate to the Human Genome Project itself and surrounding technologies, and several to long-standing research themes such as DNA repair, food mutagens, and reproductive biology. Others describe more recent developments such as computational biology, health-care technologies, and biodefense research.« less

Self-efficacy and relevance of bioscience for nursing, midwifery and healthcare students.

PubMed

Andrew, Sharon; McVicar, Andrew; Zanganeh, Mandana; Henderson, Nigel

2015-10-01

To examine nursing, midwifery and allied healthcare students' self-efficacy for science, perceived relevance of bioscience to their studies and expectations for academic success and the changes that occur after completing first-year introductory bioscience subjects. Bioscience is a foundation subject that underpins nursing, midwifery and other allied health courses. Bioscience subjects continue to be source of anxiety for students in those courses. Raising students' self-efficacy and perceptions of the importance and utility of bioscience to practice may be a way of ameliorating students' expectations and confidence in this subject area. A prospective correlational survey design. Students were surveyed in the first semester of first year and the commencement of the second year. Students were drawn from nursing, midwifery, public health and allied health courses. The surveys contained scales for self-efficacy for science, perceived relevance of bioscience to their course and personal expectations for success in their bioscience subject. Ninety-seven and 82 students completed survey 1 and 2 respectively. Twenty-six surveys could be matched. Self-efficacy increased from survey 1 to survey 2, but expectations for academic success and task value, a measure for relevance, were lower. This was statistically significant for the matched pair sample. Using a mean split, students with high self-efficacy valued science more and had higher expectations for success in their bioscience courses than those with low self-efficacy. Academic success in bioscience, confidence undertaking science tasks and perceiving bioscience as relevant to their course are interwoven concepts that are important for nursing, midwifery and applied healthcare students and ultimately for their professional practice. Literature indicates practitioners may not feel confident in their bioscience knowledge. Assisting undergraduate students to develop confidence in and perceive the relevance of bioscience to their discipline may ultimately impact on clinical practice. © 2015 John Wiley & Sons Ltd.

Sandia National Laboratories: Locations: Kauai Test Facility

Science.gov Websites

Defense Systems & Assessments About Defense Systems & Assessments Program Areas Accomplishments Foundations Bioscience Computing & Information Science Electromagnetics Engineering Science Geoscience Suppliers iSupplier Account Accounts Payable Contract Information Construction & Facilities Contract

A summary of the research program in the broad field of electronics

NASA Technical Reports Server (NTRS)

1972-01-01

Summary reports of research projects covering solid state materials, semiconductors and devices, quantum electronics, plasmas, applied electromagnetics, electrical engineering systems to include control communication, computer and power systems, biomedical engineering and mathematical biosciences.

Sustainability in Bioscience Fieldwork: Practical Information from a UK Agricultural Research Institute

ERIC Educational Resources Information Center

Wright, Hazel A.; Ironside, Joseph E.; Gwynn-Jones, Dylan

2009-01-01

Purpose: Owing to the specialist nature of biological experimentation, scientific research staff have been largely neglected from the pro-environmental initiatives which have inundated other areas of higher education. This dearth of studies is surprising given that scientific research is recognised as a substantial contributor to the environmental…

Sandia National Laboratories: Research: Bioscience

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Ahead of the Curve; Hidden breakthroughs in the biosciences

NASA Astrophysics Data System (ADS)

Levin, Michael; Adams, Dany Spencer

2016-12-01

This unique book is a compendium of carefully curated published papers in the biosciences, which have (or will) precipitate a profound change in prevailing paradigms and research programs. A mix of new and classic papers, it shows the limitations of current thought or identifies novel vistas for investigations that have not yet been explored. The purpose of the book is to highlight scientific gems, most unrecognized, that suggest revisions to key pillars of thought in the biological sciences and further the education of young scientists. This will be achieved by including reprints of papers that demonstrate counter-paradigm, novel directions for future research featuring commentary from current, notable researchers in a variety of areas.

76 FR 4692 - Notice of Receipt of Requests To Voluntarily Cancel Certain Pesticide Registrations

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-26

... Central Life Sciences, 301 West Osborn Road, Phoenix, AZ 85013. 432 Bayer Environmental Science, 2 T. W... Seaboard Industrial Blvd., NW., Atlanta, GA 30318. 62719 Dow AgroSciences LLC, 9330 Zionsville Road, 308/2E..., Cary, NC 27513. 73049 Valent BioSciences Corporation, 870 Technology Way, Suite 100, Libertyville, IL...

Effects of NIGMS Training Programs on Graduate Education in the Biomedical Sciences. An Evaluative Study of the Training Programs of the National Institute of General Medical Sciences 1958-1967.

ERIC Educational Resources Information Center

National Inst. of General Medical Sciences (NIH), Bethesda, MD.

This report was prepared by the National Research Council, at the request of the National Institutes of Health, in an attempt to evaluate the Graduate Research Training Grant Program and Fellowship Program in bioscience. One of the purposes of the study was to collect objective data that would provide answers to such questions as: What have been…

An Internship May Not Be Enough: Enhancing Bioscience Industry Job Readiness through Practicum Experiences.

PubMed

Cramer, Jason M; Hamilton, Paul T

2017-04-01

In contrast to the narrowing of options in academic careers, the bioscience industry offers robust employment opportunities for STEM-trained workers, especially those who display both scientific and business talent. Unfortunately, traditional science programs typically lack curricular features that develop this type of worker. The North Carolina State University Master of Microbial Biotechnology (MMB) program facilitates industry-specific experiential learning to fill this training gap. Similar programs often rely on a single industry internship to provide students relevant work experience, but completion of one internship might not suffice to position students for employment in a highly competitive job market. The MMB program requires students to complete an internship and three practicum projects in an industry setting, to promote development of key skills in a variety of areas, to build confidence in the ability to perform initial job duties, and to establish a more extensive work history in industry. In this Perspective we discuss an unmet need in undergraduate and graduate STEM education that can be filled by incorporating a similar set of industry-specific work experiences for students who desire to transition from academe into the life science industry.

Biosciences in nurse education: is the curriculum fit for practice? Lecturers' views and recommendations from across the UK.

PubMed

Taylor, Vanessa; Ashelford, Sarah; Fell, Patricia; Goacher, Penelope J

2015-10-01

This study aims to review the biosciences component of preregistration nursing programmes in higher education institutions across the UK through the experiences and perceptions of lecturers involved in nursing education. Studies suggest that some qualified nurses lack confidence in explaining the bio-scientific rationale for their clinical practice. Biosciences can be difficult to understand and integrate into clinical decision-making and require protected time within preregistration nurse education. In the absence of explicit national guidelines, it is unclear as to the depth and extent biosciences are taught across different institutions and the level achieved at the point of registration. A survey approach was adopted to generate quantitative and qualitative feedback. Data were collected using a semi-structured questionnaire seeking the experiences and views of lecturers involved in teaching biosciences to nursing students across the UK. Data received from 10 institutions were analysed using descriptive statistics and thematic analysis. Lecturers reported that the hours of taught biosciences ranged from 20-113 hours, principally within the first year. This represents between 0·4-2·4% of time within a preregistration nursing programme (4600 hours). Large group lectures predominate, supplemented by smaller group or practical work, and online materials. The biosciences are assessed specifically in half the institutions surveyed and as part of integrated assessments in the rest. In relation to student feedback, all respondents stated that students consistently requested more time and greater priority for biosciences in their programme. This survey suggests that the number of hours spent teaching biosciences is minimal and varies widely between higher education institutions. All respondents expressed concern about the challenges of teaching difficult bio-scientific concepts to large groups in such a limited time and called for greater clarity in national guidelines to ensure that all nurses are adequately educated and assessed in bioscience subjects. Failure to understand the biosciences underpinning care has implications for safe and competent nursing. © 2015 John Wiley & Sons Ltd.

Preregistration nursing students' perspectives on the learning, teaching and application of bioscience knowledge within practice.

PubMed

Molesworth, Mark; Lewitt, Moira

2016-03-01

This paper aims to explore student nurses' experiences of bioscience learning, teaching and application within the practice setting. It draws upon the social learning theory of communities of practice to consider the issues raised. The teaching of bioscience within many nursing curricula has shifted from traditional to more integrated approaches. Student nurses recognise bioscience as a valuable component of their studies, but many find it challenging. The focus of previous research in this area has often focussed on bioscience learning in theoretical rather than practice settings. A phenomenological study. Data were collected via focus group or interview with a total of seven students across two campuses in a Scottish university. Participants were offered the opportunity to share their experiences at both the end of year one and year two of their studies. A thematic analysis was undertaken independently then jointly by the authors. The findings suggest that although participants recognise the value of bioscience within practice settings, they found that opportunities for learning were often limited. Bioscience-related learning, teaching and application was perceived to have been given less legitimacy by the practice setting than other aspects of placement activity. To enhance bioscience approaches participants expressed a desire for more structured and integrated approaches within both practice and university along with further peer learning opportunities. Students recognise that bioscience knowledge is important in relation to the provision of safe and effective care. They request greater structure and consistency in relation to the learning, teaching and application of this topic during their placements. Those with a stake in educating nurses within clinical settings may find the views of student nurses on the topic of bioscience learning useful when planning and facilitating placement experiences. © 2015 John Wiley & Sons Ltd.

Pioneering Partnerships for Progress

ERIC Educational Resources Information Center

Borden, Sam

2006-01-01

This paper presents a brief description of the Center for Bioscience and the Integration of Computer and Telecommunications Technology (BioCATT) at Gateway Technical College in Kenosha, Wisconsin. BioCATT is designed to serve as a catalyst for innovation in educational programming, business services, and technology applications.

Laboratory directed research and development. FY 1995 progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vigil, J.; Prono, J.

1996-03-01

This document presents an overview of Laboratory Directed Research and Development Programs at Los Alamos. The nine technical disciplines in which research is described include materials, engineering and base technologies, plasma, fluids, and particle beams, chemistry, mathematics and computational science, atmic and molecular physics, geoscience, space science, and astrophysics, nuclear and particle physics, and biosciences. Brief descriptions are provided in the above programs.

Electron-Scavenging Chemistry of Benzoquinone on TiO2(110)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Henderson, Michael A.; Shen, Mingmin

The chemistry of benzoquinone (BQ) on TiO2(110) was examined using temperature programmed desorption (TPD), electron energy loss spectroscopy (EELS) and Auger electron spectroscopy (AES). BQ adsorbs mostly molecularly on the clean surface, although EELS demonstrates that electrons from surface Ti3+ sites at oxygen vacancy sites (VO) are readily oxidized by the high electron scavenging ability of the molecule. In contrast, when the surface is covered with water, subsequently adsorbed BQ molecules that scavenge surface electrons also abstract H from surface OHbr groups to form hydroquinone (HQ), which desorbs at ~450 K. This work was supported by the US Department ofmore » Energy, Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences & Biosciences. Pacific Northwest National Laboratory (PNNL) is a multiprogram national laboratory operated for DOE by Battelle. The research was performed using the Environmental Molecular Sciences Laboratory (EMSL), a national scientific user facility sponsored by the Department of Energy's Office of Biological and Environmental Research and located at Pacific Northwest National Laboratory.« less

Advancing student nurse knowledge of the biomedical sciences: A mixed methods study.

PubMed

Craft, Judy; Christensen, Martin; Bakon, Shannon; Wirihana, Lisa

2017-01-01

Nursing students' ability to learn, integrate and apply bioscience knowledge to their clinical practice remains a concern. To evaluate the implementation, influence, and student perspective of a team-teaching workshop to integrate bioscience theory with clinical nursing practice. The team-teaching workshop was offered prior to commencement of the university semester as a refresher course at an Australian university. This study employed a sequential explanatory mixed methods design incorporating both quantitative and qualitative items. An evaluation survey with quantitative and qualitative items and a focus group were employed. The qualitative data were analysed using a thematic approach. The quantitative data was combined with the emergent themes in the qualitative data. Participants were final year nursing students. Nine students attended the workshop. All students completed the evaluation (N=9) and 44.4% (N=4) attended the focus group. The results revealed six themes: (1) lectures are an inadequate teaching strategy for bioscience; (2) teaching strategies which incorporate active learning engage students; (3) the team-teaching workshop provides an effective learning environment; (4) the workshop content should be expanded; (5) pharmacology should relate to bioscience, and bioscience should relate to nursing; and (6) team-teaching was effective in integrating pharmacology with bioscience, and then translating this into nursing practice. Students had felt there was disjointedness between pharmacology and bioscience, and between bioscience and nursing care within their undergraduate studies. The workshop that was based on team-teaching bridged those gaps, utilised active learning strategies and provided an effective learning environment. Team-teaching that employs active learning strategies is an effective approach to assist nursing students to integrate bioscience knowledge into their nursing practice. Copyright © 2016 Elsevier Ltd. All rights reserved.

Environmental Biosciences Program Quarterly Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lawrence C. Mohr, M.D.

2009-01-30

Current research projects have focused Environmental Biosciences Program (EBP) talent and resources on providing the scientific basis for risk-based standards, risk-based decision making and the accelerated clean-up of widespread environmental hazards. These hazards include trichloroethylene, low-dose ionizing radiation (gamma and neutron) and alpha radiation from plutonium. Trichloroethylene research has been conducted as a joint collaborative effort with the University of Georgia. Work on the trichloroethylene research projects has been slowed as a result of funding uncertainties. The impact of these funding uncertainties has been discussed with the United States Department of Energy (DOE). Laboratory work has been completed on severalmore » trichloroethylene risk assessment projects, and these projects have been brought to a close. Plans for restructuring the performance schedule of the remaining trichloroethylene projects have been submitted to the department. A comprehensive manuscript on the scientific basis of trichloroethylene risk assessment is in preparation. Work on the low-dose radiation risk assessment projects is also progressing at a slowed rate as a result of funding uncertainties. It has been necessary to restructure the proponency and performance schedule of these projects, with the project on Low-Dose Radiation: Epidemiology Risk Models transferred to DOE Office of Science proponency under a separate funding instrument. Research on this project will continue under the provisions of the DOE Office of Science funding instrument, with progress reported in accordance with the requirements of that funding instrument. Progress on that project will no longer be reported in quarterly reports for DE-FC09-02CH11109. Following a meeting at the Savannah River Site on May 8, 2008, a plan was submitted for development of an epidemiological cohort study and prospective medical surveillance system for the assessment of disease rates among workers at the Savannah River Site (SRS). This project will be incorporated into the ongoing project on Population Health Risks in the Vicinity of the Savannah River Site. During a meeting at the SRS on October 21, 2008, a presentation was made on EBP participation in the development and operation of an Epidemiology Consortium at the SRS. A follow-up meeting with SRS officials is planned for 29 and 30 January 2009 at Medical University of South Carolina (MUSC).An epidemiology project on population health risk assessment is being conducted to assess health risks among populations in the vicinity of the SRS. This project is using the capabilities of the EBP GIS for the geographical assessment of cancer and non-cancer disease rates, as well as the potential association of population health risks with environmental exposures. Although funding uncertainties have slowed progress on some aspects of this project, it has not been necessary to restructure the performance schedule to date.« less

Bioinformatics for Undergraduates: Steps toward a Quantitative Bioscience Curriculum

ERIC Educational Resources Information Center

Chapman, Barbara S.; Christmann, James L.; Thatcher, Eileen F.

2006-01-01

We describe an innovative bioinformatics course developed under grants from the National Science Foundation and the California State University Program in Research and Education in Biotechnology for undergraduate biology students. The project has been part of a continuing effort to offer students classroom experiences focused on principles and…

Biology Students Building Computer Simulations Using StarLogo TNG

ERIC Educational Resources Information Center

Smith, V. Anne; Duncan, Ishbel

2011-01-01

Confidence is an important issue for biology students in handling computational concepts. This paper describes a practical in which honours-level bioscience students simulate complex animal behaviour using StarLogo TNG, a freely-available graphical programming environment. The practical consists of two sessions, the first of which guides students…

The Systems Approach to Functional Job Analysis. Task Analysis of the Physician's Assistant: Volume II--Curriculum and Phase I Basic Core Courses and Volume III--Phases II and III--Clinical Clerkships and Assignments.

ERIC Educational Resources Information Center

Wake Forest Univ., Winston Salem, NC. Bowman Gray School of Medicine.

This publication contains a curriculum developed through functional job analyses for a 24-month physician's assistant training program. Phase 1 of the 3-phase program is a 6-month basic course program in clinical and bioscience principles and is required of all students regardless of their specialty interest. Phase 2 is a 6 to 10 month period of…

Multimedia Interactive eBooks in Laboratory Bioscience Education

ERIC Educational Resources Information Center

Morris, Neil P.; Lambe, James

2017-01-01

Bioscience students in the UK higher education system are making increasing use of technology to support their learning within taught classes and during private study. This experimental study was designed to assess the role for multimedia interactive eBooks in bioscience laboratory classes, delivered using a blended learning approach. Thirty-nine…

What is provided and what the registered nurse needs--bioscience learning through the pre-registration curriculum.

PubMed

Davis, Geraldine M

2010-11-01

Registered nurses undertaking programmes of study to become non-medical prescribers appear to have limited biological science knowledge. A case study was undertaken to determine whether the nurses entering Prescriber programmes considered studies in bioscience in their pre-registration nursing courses had been sufficient, linked to practice, and had prepared them for their roles as registered nurses. The literature identifies a continuing trend amongst nursing students describing a lack of sufficient bioscience in initial nurse education; there is limited literature on the views of experienced registered nurses. The participants in this study were 42 registered nurses from adult and mental health nursing, community and inpatient services. The results obtained from questionnaires and interviews are described. Questionnaire analysis identified that 57.1% of participants indicated bioscience in their pre-registration nursing programme had been limited and 40.5% stated the bioscience content had not prepared them for their roles on registration. Those reporting extensive coverage of bioscience were all aged over 41 years and had qualified before 1995. Greatest coverage of bioscience in pre-registration programmes was reported in relation to anatomy and physiology, with relatively limited coverage of microbiology, pharmacology or biochemistry. Respondents considered all five topics to be important. Interviews supported the questionnaire findings. Copyright © 2010 Elsevier Ltd. All rights reserved.

Defining the Problem: Mathematical Errors and Misconceptions Exhibited by First-Year Bioscience Undergraduates

ERIC Educational Resources Information Center

Tariq, V. N.

2008-01-01

This study extends the debate concerning the mathematical skills deficit of bioscience undergraduates towards a deeper understanding of their mathematics learning, since only through the latter can appropriate and effective explicit teaching be implemented. Three hundred and twenty-six first-year bioscience undergraduates, from three pre- and four…

75 FR 64733 - Arcadia Biosciences, Inc.; Filing of Food Additive Petition (Animal Use); Safflower Seed Meal

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-20

...] Arcadia Biosciences, Inc.; Filing of Food Additive Petition (Animal Use); Safflower Seed Meal AGENCY: Food... announcing that Arcadia Biosciences, Inc., has filed a petition proposing that the food additive regulations..., Davis, CA 95618. The petition proposes to amend the food additive regulations in part 573 Food Additives...

Integrating Standard Operating Procedures and Industry Notebook Standards to Evaluate Students in Laboratory Courses

ERIC Educational Resources Information Center

Wallert, Mark A.; Provost, Joseph J.

2014-01-01

To enhance the preparedness of graduates from the Biochemistry and Biotechnology (BCBT) Major at Minnesota State University Moorhead for employment in the bioscience industry we have developed a new Industry certificate program. The BCBT Industry Certificate was developed to address specific skill sets that local, regional, and national industry…

New Directions for Biosciences Research in Agriculture. High-Reward Opportunities.

ERIC Educational Resources Information Center

National Academy of Sciences - National Research Council, Washington, DC. Board on Agriculture.

To aid in the effort to define comprehensive long-range planning goals in bioregulation, the Agricultural Research Service (ARS) asked the Board of Agriculture of the National Research Council to undertake a study of the ARS research programs concerned with bioregulation. (For the purposes of this study bioregulation was interpreted broadly to be…

Active Hydrogenation Catalyst with a Structured, Peptide-Based Outer-Coordination Sphere

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jain, Avijita; Buchko, Garry W.; Reback, Matthew L.

2012-10-05

The synthesis, catalytic activity, and structural features of a rhodium-based hydrogenation catalyst containing a phosphine ligand coupled to a 14-residue peptide are reported. Both CD and NMR spectroscopy show that the peptide adopts a helical structure in 1:1:1 TFE/MeCN/H2O that is maintained when the peptide is attached to the ligand and when the ligand is attached to the metal complex. The metal complex hydrogenates aqueous solutions of 3-butenol to 1-butanol at 360 ± 50 turnovers/Rh/h at 294 K. This peptide- based catalyst represents a starting point for developing and characterizing a peptide-based outer-coordination sphere that can be used to introducemore » enzyme-like features into molecular catalysts. This work was funded by the US DOE Basic Energy Sciences, Chemical Sciences, Geoscience and Biosciences Division (AJ, JCL and WJS), the Office of Science Early Career Research Program through the Office of Basic Energy Sciences (GWB, MLR and WJS). Part of the research was conducted at the W.R. Wiley Environmental Molecular Sciences Laboratory, a national scientific user facility sponsored by U.S. Department of Energy’s Office of Biolog-ical and Environmental Research (BER) program located at Pacific Northwest National Laboratory (PNNL). PNNL is operated by Battelle for the U.S. Department of Energy.« less

The Future of Bioscience Fieldwork in UK Higher Education

ERIC Educational Resources Information Center

Mauchline, Alice L.; Peacock, Julie; Park, Julian R.

2013-01-01

Fieldwork is an important and often enjoyable part of learning in Bioscience degree courses, however it is unclear how the recent reforms to Higher Education (HE) may impact the future funding of outdoor learning. This paper reports on the findings from a recent survey of 30 HE Bioscience practitioners from across the UK. Their current level of…

The 'bioscience problem' for nursing students: an integrative review of published evaluations of Year 1 bioscience, and proposed directions for curriculum development.

PubMed

McVicar, Andrew; Andrew, Sharon; Kemble, Ross

2015-03-01

The difficulties that nursing students have in learning human biosciences have given cause for concern for over 20 years but the problem remains. To conduct an integrative review of published primary research into the 'bioscience problem', evaluate their outcomes, and provide a contemporary analysis of potential directions for curriculum planners. A systematic search of electronic databases CINAHL, Medline, British Nursing Index and Google Scholar was conducted for empirical research studies, published between 1990 and 2013, designed to either predict performance of students in bioscience assessments in Year 1 of their studies or identify in-course curriculum delivery issues. The search generated nineteen papers that met inclusion criteria. Twelve papers involved predictive factors for bioscience attainment and seven surveyed student views on curriculum issues. Four others that surveyed reflections of later-year students or qualified nurses on Year 1 outcomes were also retained for additional context. Prediction based on pre-admission academic achievement was not reliable. Student factors including age at entry, self-efficacy in science, and having appropriate study skills in particular appear to be confounding factors. In-course influences such as teaching strategy or lecturer skills are also inconsistent and likely to represent confounders operating at local, institutional level. The integrative review approach enabled analysis of incongruencies between studies that have been a barrier to curriculum development. Sound admissions criteria based on pre-university academic performance show promise in resolving the 'bioscience problem' but will likely be contingent on innovative support early in Year 1 for study skills and the fundamentals of human bioscience, plus attention to local quality assurance for curriculum delivery. Copyright © 2014 Elsevier Ltd. All rights reserved.

Students Turned Off by Turnitin? Perception of Plagiarism and Collusion by Undergraduate Bioscience Students

ERIC Educational Resources Information Center

Thompsett, Andrew; Ahluwalia, Jatinder

2010-01-01

Research on undergraduate bioscience students and the incidence of plagiarism is still in its infancy and a key problem arises in gauging the perception of undergraduate students on plagiarism and collusion in biosciences subjects because of the lack of empirical data. The aim of this study was to provide qualitative data on the perceptions of…

Bench to Bedside: The Effectiveness of a Professional Development Program Focused on Biomedical Sciences and Action Research

PubMed Central

Barnes, Marianne B.; Barnes, Lehman W.; Cooper, Lou Ann; Bokor, Julie R.; Koroly, Mary Jo

2017-01-01

A three-year, National Institutes of Health-funded residential project at a southeastern research university immersed 83 secondary science teachers in a summer institute called “Bench to Bedside.” Teachers were provided with knowledge, skills, experiences, and incentives to improve their science teaching and increase their awareness of scientific processes, technologies, and careers by examining the translational medicine continuum of basic to clinical research. This was done with the help of medical school researchers, clinical personnel, biotechnology entrepreneurs, program mentors, and prior year participants. A critical component of the institute was the preparation and implementation of an action research project that reflected teachers’ newly acquired knowledge and skills. Action research proposals were critiqued by project team members and feedback provided prior to action research implementation in schools during the following year. Teachers shared their action research with colleagues and project team at a symposium and online as a critical step in networking the teachers. Results of a mixed methods program evaluation strategy indicate that the program produced significant gains in teachers’ confidence to explain advanced biosciences topics, development of action research skills, and formation of a statewide biosciences network of key stakeholders. Constraints of time, variation in teacher content and action research background, technology availability, and school-related variables, among others, are discussed. PMID:29733086

Saturday Morning Science programs: a model to increase diversity in the biosciences.

PubMed

Phillips, James L; Harris, Toi Blakley; Ihedigbo, Kara M Green; Hawkins, Jacqueline

2012-01-01

To examine a pathway program for middle and high school students from underrepresented backgrounds designed to foster career interest in the biomedical sciences. In 2002, the Institute of Medicine released a report entitled Unequal Treatment, which examined the racial and ethnic disparities in health and health care within the United States and encouraged the development of a diverse health care workforce as a means to reduce health care disparities. Saturday Morning Science (SMS) is a program model presented as a pipeline strategy that addresses this specific recommendation. SMS is a 10-week program that emphasized the importance of science and math. Post-SMS evaluations were conducted to assess biomedical career knowledge, attitudes regarding future career plans, and the effectiveness of the program. A total of 87.5% of middle and high school students who were enrolled in SMS completed the program (113 of 130). Seventy percent of SMS participants were underrepresented minorities. Snapshot program evaluation data exposed new ideas about science (strongly agree/agree, 98%; 64 of 65), exposed new ideas about medicine (strongly agree/agree, 97%; 63 of 65, and increased desire to enter science related field (strongly agree/agree 82% (53 of 65). SMS was designed to motivate students of underrepresented ethnic backgrounds from middle through high school to attend college and prepare for careers in the health sciences. SMS students had the opportunity to interact with scientists, physicians, medical and graduate students, and other academicians. They provided direction and guidance to ensure that students had meaningful experiences specifically designed to expose them to opportunities in the biosciences.

Reflective Writing as a Tool for Assessing Teamwork in Bioscience: Insights into Student Performance and Understanding of Teamwork

ERIC Educational Resources Information Center

Mayne, Lynne

2012-01-01

To ensure a modern bioscience curriculum that responds to the current needs of stakeholders, there is a need to embed a range of generic capabilities that enables graduates to succeed in and contribute to a rapidly changing world, as well as building strong bioscience skills and knowledge. The curriculum must also prepare students for a rapidly…

The Story of a Typical Atypical Graduate of the Physics Entrepreneurship Program at Case Western Reserve University

NASA Astrophysics Data System (ADS)

Luta, Adele

2012-02-01

An entrepreneurial perspective to life can lead to wearing a myriad of hats. Long gone is the stereotypical start-up role. Entrepreneurs now hold physics degrees and procure innovation when called upon. An alumni of the Physics Entrepreneurship Program, Adele Luta has spent the last 5 years at NASA developing an innovative approach to spacesuit sizing. Previously, she founded Eleda International consulting firm and is currently working with Adjuvat Biosciences, on a proprietary treatment pancreatic cancer.

Can active learning principles be applied to the bioscience assessments of nursing students? A review of the literature.

PubMed

Bakon, Shannon; Craft, Judy; Christensen, Martin; Wirihana, Lisa

2016-02-01

To explore if active learning principles be applied to nursing bioscience assessments and will this influence student perception of confidence in applying theory to practice? A review of the literature utilising searches of various databases including CINAHL, PUBMED, Google Scholar and Mosby's Journal Index. The literature search identified research from twenty-six original articles, two electronic books, one published book and one conference proceedings paper. Bioscience has been identified as an area that nurses struggle to learn in tertiary institutions and then apply to clinical practice. A number of problems have been identified and explored that may contribute to this poor understanding and retention. University academics need to be knowledgeable of innovative teaching and assessing modalities that focus on enhancing student learning and address the integration issues associated with the theory practice gap. Increased bioscience education is associated with improved patient outcomes therefore by addressing this "bioscience problem" and improving the integration of bioscience in clinical practice there will subsequently be an improvement in health care outcomes. From the literature several themes were identified. First there are many problems with teaching nursing students bioscience education. These include class sizes, motivation, concentration, delivery mode, lecturer perspectives, student's previous knowledge, anxiety, and a lack of confidence. Among these influences the type of assessment employed by the educator has not been explored or identified as a contributor to student learning specifically in nursing bioscience instruction. Second that educating could be achieved more effectively if active learning principles were applied and the needs and expectations of the student were met. Lastly, assessment influences student retention and the student experience and as such assessment should be congruent with the subject content, align with the learning objectives and be used as a stimulus tool for learning. Copyright © 2015 Elsevier Ltd. All rights reserved.

Nursing students collaborating to develop multiple-choice exam revision questions: A student engagement study.

PubMed

Craft, Judy A; Christensen, Martin; Shaw, Natasha; Bakon, Shannon

2017-12-01

Nursing students find bioscience subjects challenging. Bioscience exams pose particular concerns for these students, which may lead to students adopting a surface-approach to learning. To promote student collective understanding of bioscience, improve their confidence for the final exam, and improve deeper understanding of bioscience. In order to address exam anxiety, and improve student understanding of content, this student engagement project involved nursing students collaborating in small groups to develop multiple-choice questions and answers, which became available to the entire student cohort. This study was conducted at two campuses of an Australian university, within a first year bioscience subject as part of the undergraduate nursing programme. All students enrolled in the subject were encouraged to attend face-to-face workshops, and collaborate in revision question writing. Online anonymous questionnaires were used to invite student feedback on this initiative; 79 respondents completed this feedback. Students collaborated in groups to write revision questions as part of in-class activities. These questions were made available on the student online learning site for revision. An online feedback survey was deployed at the conclusion of all workshops for this subject, with questions rated using a Likert scale. Participants indicated that they enjoyed the opportunity to collaborate in this activity, and almost all of these respondents used these questions in their exam preparation. There was strong agreement that this activity improved their confidence for the final exam. Importantly, almost two-thirds of respondents agreed that writing questions improved their understanding of content, and assisted in their active reflection of content. Overall, this initiative revealed various potential benefits for the students, including promoting bioscience understanding and confidence. This may improve their long-term understanding of bioscience for nursing practice, as registered nurses' bioscience knowledge can impact on patient outcomes. Copyright © 2017 Elsevier Ltd. All rights reserved.

Is LabTutor a helpful component of the blended learning approach to biosciences?

PubMed

Swift, Amelia; Efstathiou, Nikolaos; Lameu, Paula

2016-09-01

To evaluate the use of LabTutor (a physiological data capture and e-learning package) in bioscience education for student nurses. Knowledge of biosciences is important for nurses the world over, who have to monitor and assess their patient's clinical condition, and interpret that information to determine the most appropriate course of action. Nursing students have long been known to find acquiring useable bioscience knowledge challenging. Blended learning strategies are common in bioscience teaching to address the difficulties students have. Student nurses have a preference for hands-on learning, small group sessions and are helped by close juxtaposition of theory and practice. An evaluation of a new teaching method using in-classroom voluntary questionnaire. A structured survey instrument including statements and visual analogue response format and open questions was given to students who participated in Labtutor sessions. The students provided feedback in about the equipment, the learning and the session itself. First year (n = 93) and third year (n = 36) students completed the evaluation forms. The majority of students were confident about the equipment and using it to learn although a few felt anxious about computer-based learning. They all found the equipment helpful as part of their bioscience education and they all enjoyed the sessions. This equipment provides a helpful way to encourage guided independent learning through practice and discovery and because each session is case study based and the relationship of the data to the patient is made clear. Our students helped to evaluate our initial use of LabTutor and found the sessions enjoyable and helpful. LabTutor provides an effective learning tool as part of a blended learning strategy for biosciences teaching. Improving bioscience knowledge will lead to a greater understanding of pathophysiology, treatments and interventions and monitoring. © 2016 John Wiley & Sons Ltd.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Peter L; Rhyne, James J

The unique properties of synchrotron radiation are its continuous spectrum, high flux and brightness, and high coherence, which make it an indispensable tool in the exploration of matter. The wavelengths of the emitted photons span a range of dimensions from the atomic level to biological cells, thereby providing incisive probes for advanced research in materials science, physical and chemical sciences, metrology, geosciences, environmental sciences, biosciences, medical sciences, and pharmaceutical sciences. The features of synchrotron radiation are especially well matched to the needs of nanoscience.

High pressure in bioscience and biotechnology: pure science encompassed in pursuit of value.

PubMed

Hayashi, Rikimaru

2002-03-25

A fundamental factors, pressure (P), is indispensable to develop and support applications in the field of bioscience and biotechnology. This short sentence describes an example how high pressure bioscience and biotechnology, which started from applied science, stimulates challenges of basic science and pure science in the biology-related fields including not only food science, medicine, and pharmacology but also biochemistry, molecular biology, cell biology, physical chemistry, and engineering.

New Sensors to Track Head Acceleration during Possible Injurious Events

DTIC Science & Technology

2009-02-01

Chris Perry John Plaga Biosciences and Protection Division Biomechanics Branch Jesse Bonfeld Endevco 30700 Rancho Viejo Road San Juan...GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 62202F 6. AUTHOR(S) Ted Knox, Joseph Pellettiere, Chris Perry, John Plaga Jesse Bonfeld 5d...Possible Injurious Events Ted Knox, Joseph Pellettiere, Chris Perry, John Plaga AFRL/RHPA Jesse Bonfeld Endevco ABSTRACT Instrumented

Bio-TDS: bioscience query tool discovery system.

PubMed

Gnimpieba, Etienne Z; VanDiermen, Menno S; Gustafson, Shayla M; Conn, Bill; Lushbough, Carol M

2017-01-04

Bioinformatics and computational biology play a critical role in bioscience and biomedical research. As researchers design their experimental projects, one major challenge is to find the most relevant bioinformatics toolkits that will lead to new knowledge discovery from their data. The Bio-TDS (Bioscience Query Tool Discovery Systems, http://biotds.org/) has been developed to assist researchers in retrieving the most applicable analytic tools by allowing them to formulate their questions as free text. The Bio-TDS is a flexible retrieval system that affords users from multiple bioscience domains (e.g. genomic, proteomic, bio-imaging) the ability to query over 12 000 analytic tool descriptions integrated from well-established, community repositories. One of the primary components of the Bio-TDS is the ontology and natural language processing workflow for annotation, curation, query processing, and evaluation. The Bio-TDS's scientific impact was evaluated using sample questions posed by researchers retrieved from Biostars, a site focusing on BIOLOGICAL DATA ANALYSIS: The Bio-TDS was compared to five similar bioscience analytic tool retrieval systems with the Bio-TDS outperforming the others in terms of relevance and completeness. The Bio-TDS offers researchers the capacity to associate their bioscience question with the most relevant computational toolsets required for the data analysis in their knowledge discovery process. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

Predictors of academic performance in the discipline-specific bioscience paper: a retrospective qualitative study.

PubMed

Khareedi, R

2018-05-01

The cohort of students enrolled in the discipline-specific bioscience paper reflects a structural diversity in that it includes students of multiple ethnicities, varied age groups, differing scholastic and life experiences. These divergent identities of students are known to influence academic performance. The purpose of this retrospective quantitative study was to determine the ability of a set of variables such as age, gender, ethnicity, level of prior education, the place from which prior education was obtained, work experience and prior academic achievement to predict academic performance in the discipline-specific bioscience paper. The sample for this study was a purposive sample of all oral health students who had enrolled in the paper at the Auckland University of Technology from 2011 to 2014. The desensitised empirical data of 116 students from the University's database were subject to multivariable regression analysis. Pearson's correlation coefficients were calculated. Prior academic achievement was a statistically significant predictor variable (P < 0.001) for the academic performance in the discipline-specific bioscience paper and was also positively correlated (r = 0.641, P < 0.001) to the grades in the discipline-specific bioscience paper. Prior academic achievement was the only variable that was demonstrated to be correlated to and predictive of the academic performance in the discipline-specific bioscience paper. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Automatic Figure Ranking and User Interfacing for Intelligent Figure Search

PubMed Central

Yu, Hong; Liu, Feifan; Ramesh, Balaji Polepalli

2010-01-01

Background Figures are important experimental results that are typically reported in full-text bioscience articles. Bioscience researchers need to access figures to validate research facts and to formulate or to test novel research hypotheses. On the other hand, the sheer volume of bioscience literature has made it difficult to access figures. Therefore, we are developing an intelligent figure search engine (http://figuresearch.askhermes.org). Existing research in figure search treats each figure equally, but we introduce a novel concept of “figure ranking”: figures appearing in a full-text biomedical article can be ranked by their contribution to the knowledge discovery. Methodology/Findings We empirically validated the hypothesis of figure ranking with over 100 bioscience researchers, and then developed unsupervised natural language processing (NLP) approaches to automatically rank figures. Evaluating on a collection of 202 full-text articles in which authors have ranked the figures based on importance, our best system achieved a weighted error rate of 0.2, which is significantly better than several other baseline systems we explored. We further explored a user interfacing application in which we built novel user interfaces (UIs) incorporating figure ranking, allowing bioscience researchers to efficiently access important figures. Our evaluation results show that 92% of the bioscience researchers prefer as the top two choices the user interfaces in which the most important figures are enlarged. With our automatic figure ranking NLP system, bioscience researchers preferred the UIs in which the most important figures were predicted by our NLP system than the UIs in which the most important figures were randomly assigned. In addition, our results show that there was no statistical difference in bioscience researchers' preference in the UIs generated by automatic figure ranking and UIs by human ranking annotation. Conclusion/Significance The evaluation results conclude that automatic figure ranking and user interfacing as we reported in this study can be fully implemented in online publishing. The novel user interface integrated with the automatic figure ranking system provides a more efficient and robust way to access scientific information in the biomedical domain, which will further enhance our existing figure search engine to better facilitate accessing figures of interest for bioscientists. PMID:20949102

A Comparison between Flash and Second Life Programs as Aids in the Learning of Basic Laboratory Procedures

ERIC Educational Resources Information Center

Booth, Paula; Henderson-Begg, Stephanie

2011-01-01

Invited as a paper from E-Learn 2009 This study compared two programmes developed as a learning tool for students to practise basic laboratory procedures. One was a Flash simulation programme, the other a Second Life virtual reality programme. A cohort of 93 bioscience students participated in the between trial. A control group was used to…

A Decline in Numeracy Skills among Bioscience Undergraduates.

ERIC Educational Resources Information Center

Tariq, Vicki N.

2002-01-01

Provides evidence of a decline in basic numeracy skills among first-year bioscience undergraduate students. Tests conceptualized numeracy skills which form a component of an introductory microbiology module. (Contains 23 references.) (Author/YDS)

Promoting active learning using audience response system in large bioscience classes.

PubMed

Efstathiou, Nikolaos; Bailey, Cara

2012-01-01

This paper considers the challenges of bioscience teaching and learning in pre-registration nurse education. Effective learning requires active student participation which is problematic when teaching large groups of students. New technologies, such as the audience response system (ARS), have been introduced to increase student participation and support them in the understanding of complex bioscience concepts. Within one university department, an evaluation was undertaken to identify the perceptions of pre-registration nurse students on the use of ARS in the teaching and learning of bioscience. Our findings concur with others that ARS increases student participation and aids in identifying misconceptions and in correcting them. Students found ARS very useful and wanted ARS to be used in additional modules too. Although ARS did not seem to motivate students to study adequately before attending the relevant sessions, it increased discussion among students and awareness of their level of knowledge compared to their peers. Further research is required to identify the effectiveness of ARS in the teaching and learning of bioscience and its impact on the performance of the students in their final assessments. Copyright © 2011 Elsevier Ltd. All rights reserved.

Vegetable Oil from Leaves and Stems: Vegetative Production of Oil in a C4 Crop

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2012-01-01

PETRO Project: Arcadia Biosciences, in collaboration with the University of California-Davis, is developing plants that produce vegetable oil in their leaves and stems. Ordinarily, these oils are produced in seeds, but Arcadia Biosciences is turning parts of the plant that are not usually harvested into a source of concentrated energy. Vegetable oil is a concentrated source of energy that plants naturally produce and is easily separated after harvest. Arcadia Biosciences will isolate traits that control oil production in seeds and transfer them into leaves and stems so that all parts of the plants are oil-rich at harvest time. After demonstratingmore » these traits in a fast-growing model plant, Arcadia Biosciences will incorporate them into a variety of dedicated biofuel crops that can be grown on land not typically suited for food production« less

Facilitating long-term changes in student approaches to learning science.

PubMed

Buchwitz, Brian J; Beyer, Catharine H; Peterson, Jon E; Pitre, Emile; Lalic, Nevena; Sampson, Paul D; Wakimoto, Barbara T

2012-01-01

Undergraduates entering science curricula differ greatly in individual starting points and learning needs. The fast pace, high enrollment, and high stakes of introductory science courses, however, limit students' opportunities to self-assess and modify learning strategies. The University of Washington's Biology Fellows Program (BFP) intervenes through a 20-session, premajors course that introduces students to the rigor expected of bioscience majors and assists their development as science learners. This study uses quantitative and qualitative approaches to assess whether the 2007-2009 BFP achieved its desired short- and long-term impacts on student learning. Adjusting for differences in students' high school grade point average and Scholastic Aptitude Test scores, we found that participation in the BFP was associated with higher grades in two subsequent gateway biology courses, across multiple quarters and instructors. Two to 4 yr after participating in the program, students attributed changes in how they approached learning science to BFP participation. They reported having learned to "think like a scientist" and to value active-learning strategies and learning communities. In addition, they reported having developed a sense of belonging in bioscience communities. The achievement of long-term impacts for a short-term instructional investment suggests a practical means to prepare diverse students for the rigors of science curricula.

Facilitating Long-Term Changes in Student Approaches to Learning Science

PubMed Central

Buchwitz, Brian J.; Beyer, Catharine H.; Peterson, Jon E.; Pitre, Emile; Lalic, Nevena; Sampson, Paul D.; Wakimoto, Barbara T.

2012-01-01

Undergraduates entering science curricula differ greatly in individual starting points and learning needs. The fast pace, high enrollment, and high stakes of introductory science courses, however, limit students’ opportunities to self-assess and modify learning strategies. The University of Washington's Biology Fellows Program (BFP) intervenes through a 20-session, premajors course that introduces students to the rigor expected of bioscience majors and assists their development as science learners. This study uses quantitative and qualitative approaches to assess whether the 2007–2009 BFP achieved its desired short- and long-term impacts on student learning. Adjusting for differences in students’ high school grade point average and Scholastic Aptitude Test scores, we found that participation in the BFP was associated with higher grades in two subsequent gateway biology courses, across multiple quarters and instructors. Two to 4 yr after participating in the program, students attributed changes in how they approached learning science to BFP participation. They reported having learned to “think like a scientist” and to value active-learning strategies and learning communities. In addition, they reported having developed a sense of belonging in bioscience communities. The achievement of long-term impacts for a short-term instructional investment suggests a practical means to prepare diverse students for the rigors of science curricula. PMID:22949424

Nursing as a scientific undertaking and the intersection with science in undergraduate studies: implications for nursing management.

PubMed

Logan, Patricia A; Angel, Lyndall

2011-04-01

To explore the science-nursing tension and impact for nursing students studying bioscience. Several studies have examined why nursing students struggle to be successful in bioscience subjects. Undeveloped science background and theory-practice gaps are noted as contributing factors. A qualitative study explored the science-nursing tension with 100 Australian Registered Nurses using focus groups and a survey. The survey response rate was 85 from 550. Of survey respondents, 88% viewed nursing as an applied science. An emphasis on procedural skills and task busyness undermines theoretical understanding of care and can be a negative influence upon the student bioscience experience. Practicum mentors confident in scientific knowledge enhance the student experience of bioscience by providing opportunities for integration with practice. Competing philosophies that reinforce the science-nursing tension have an impact upon student endeavours yet the nexus created by practice can be used to activate student curiosity and scientific understanding. Nurse managers need to structure the student practicum to encompass scientific theory applied to practice with equal emphasis on task efficiency. This improves student attitudes to learning bioscience and potentially minimizes the impact of the science-nursing tension on student learning. © 2011 The Authors. Journal compilation © 2011 Blackwell Publishing Ltd.

1999 LDRD Laboratory Directed Research and Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rita Spencer; Kyle Wheeler

This is the FY 1999 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5)more » engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.« less

Laboratory Directed Research and Development FY 1998 Progress Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

John Vigil; Kyle Wheeler

This is the FY 1998 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principle investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5)more » engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.« less

Laboratory directed research and development: FY 1997 progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vigil, J.; Prono, J.

1998-05-01

This is the FY 1997 Progress Report for the Laboratory Directed Research and Development (LDRD) program at Los Alamos National Laboratory. It gives an overview of the LDRD program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic and molecular physics and plasmas, fluids, and particle beams, (5)more » engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.« less

Biosciences within the pre-registration (pre-requisite) curriculum: an integrative literature review of curriculum interventions 1990-2012.

PubMed

McVicar, Andrew; Andrew, Sharon; Kemble, Ross

2014-04-01

The learning of biosciences is well-documented to be problematic as students find the subjects amongst the most difficult and anxiety-provoking of their pre-registration programme. Studies suggest that learning consequently is not at the level anticipated by the profession. Curriculum innovations might improve the situation but the effectiveness of applied interventions has not been evaluated. To undertake an integrative review and narrative synthesis of curriculum interventions and evaluate their effect on the learning of biosciences by pre-registration student nurses. Review methods A systematic search of electronic databases CINAHL, Medline, British Nursing Index and Google Scholar for empirical research studies was designed to evaluate the introduction of a curriculum intervention related to the biosciences, published in 1990-2012. Studies were evaluated for design, receptivity of the intervention and impact on bioscience learning. The search generated fourteen papers that met inclusion criteria. Seven studies introduced on-line learning packages, five an active learning format into classroom teaching or practical sessions, and two applied Audience Response Technology as an exercise in self-testing and reflection. Almost all studies reported a high level of student satisfaction, though in some there were access/utilization issues for students using on-line learning. Self-reporting suggested positive experiences, but objective evaluation suggests that impacts on learning were variable and unconvincing even where an effect on course progress was identified. Adjunct on-line programmes also show promise for supporting basic science or language acquisition. Published studies of curriculum interventions, including on-line support, have focused too heavily on the perceived benefit to students rather than objective measures of impact on actual learning. Future studies should include rigorous assessment evaluations within their design if interventions are to be adopted to reduce the 'bioscience problem'. © 2013.

Standards for the Ph.D. Degree in the Molecular Biosciences.

ERIC Educational Resources Information Center

Vella, F.; de Meis, Leopoldo; Mehler, Alan H.; Rombauts, Wilfried; White, Harold B., III; Wood, E. J.

2000-01-01

Argues that the barriers between the traditional biosciences have disappeared while interdisciplinarity has become commonplace. Presents the suggested standards for Ph.D. degrees in biochemistry and molecular biology recommended by the Committee on Education of the International Union of Biochemistry. (Author/CCM)

Organizing human functioning and rehabilitation research into distinct scientific fields. Part I: Developing a comprehensive structure from the cell to society.

PubMed

Stucki, Gerold; Grimby, Gunnar

2007-05-01

There is a need to organize rehabilitation and related research into distinct scientific fields in order to overcome the current limitations of rehabilitation research. Based on the general distinction in basic, applied and professional sciences applicable to research in general, and the rehabilitation relevant distinction between the comprehensive perspective based on WHO's integrative model of human functioning (ICF) and the partial perspective focusing on the biomedical aspects of functioning, it is possible to identify 5 distinct scientific fields of human functioning and rehabilitation research. These are the emerging human functioning sciences and integrative rehabilitation sciences from the comprehensive perspective, the established biosciences and biomedical rehabilitation sciences and engineering from the partial perspective, and the professional rehabilitation sciences at the cutting edge of research and practice. The human functioning sciences aim to understand human functioning and to identify targets for comprehensive interventions, with the goal of contributing to the minimization of the experience of disability in the population. The biosciences in rehabilitation aim to explain body injury and repair and to identify targets for biomedical interventions. The integrative rehabilitation sciences design and study comprehensive assessments and interventions that integrate biomedical, personal factor and environmental approaches suited to optimize people's performance. The biomedical rehabilitation sciences and engineering study diagnostic measures and interventions suitable to minimize impairment, including symptom control, and to optimize people's capacity. The professional rehabilitation sciences study how to provide best care with the goal of enabling people with health conditions experiencing or likely to experience disability to achieve and maintain optimal functioning in interaction with the environment. The organization of human functioning and rehabilitation research into the 5 distinct scientific fields facilitates the development of academic training programs and career building as well as the development of research structures dedicated to human functioning and rehabilitation research.

Gender Differences in NATO Anthropometry and the Implication for Protective Equipment

DTIC Science & Technology

2008-09-01

National Research Council 2800 Q Street Wright-Patterson AFB OH 45433-7947 Kathleen M. Robinette Biomechanics Branch Biosciences and Protection...Air Force Research Laboratory Human Effectiveness Directorate Biosciences and Protection Division Biomechanics ...BARRY REEDER, Work Unit Manager MARK M. HOFFMAN, Deputy Chief Biomechanics

Space Biosciences, Space-X, and the International Space Station

NASA Technical Reports Server (NTRS)

Wigley, Cecilia

2014-01-01

Space Biosciences Research on the International Space Station uses living organisms to study a variety of research questions. To enhance our understanding of fundamental biological processes. To develop the fundations for a safe, productive human exploration of space. To improve the quality of life on earth.

Electrocatalytic Oxidation of Formate with Nickel Diphosphane Dipeptide Complexes. Effect of Ligands Modified with Amino Acids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Galan, Brandon R.; Reback, Matthew L.; Jain, Avijita

2013-09-03

A series of nickel bis-diphosphine complexes with dipeptides appended to the ligands were investigated for the catalytic oxidation of formate. Typical rates of ~7 s -1 were found, similar to the parent complex (~8 s -1), with amino acid size and positioning contributing very little to rate or operating potential. Hydroxyl functionalities did result in lower rates, which were recovered by protecting the hydroxyl group. The results suggest that the overall dielectric introduced by the dipeptides does not play an important role in catalysis, but free hydroxyl groups do influence activity suggesting contributions from intra- or intermolecular interactions. These observationsmore » are important in developing a fundamental understanding of the affect that an enzyme-like outer coordination sphere can have upon molecular catalysts. This work was funded by the US DOE Basic Energy Sciences, Chemical Sciences, Geoscience and Biosciences Division (BRG, AJ, AMA, WJS), the US DOE Basic Energy Sciences, Physical Bioscience program (MLR). Pacific Northwest National Laboratory is operated by Battelle for the U.S. Department of Energy.« less

Kotov works with samples from the Bioscience Experiment ASEPTIC during Joint Operations

NASA Image and Video Library

2010-02-19

ISS022-E-068638 (18 Feb. 2010) --- Russian cosmonaut Oleg Kotov, Expedition 22 flight engineer, works with samples from the bioscience experiment ASEPTIC (BTKh-39) in the new Russian Glavboks-S (Glovebox) located in the Poisk Mini-Research Module 2 (MRM2) of the International Space Station.

Kotov works with samples from the Bioscience Experiment ASEPTIC during Joint Operations

NASA Image and Video Library

2010-02-19

ISS022-E-068640 (18 Feb. 2010) --- Russian cosmonaut Oleg Kotov, Expedition 22 flight engineer, works with samples from the bioscience experiment ASEPTIC (BTKh-39) in the new Russian Glavboks-S (Glovebox) located in the Poisk Mini-Research Module 2 (MRM2) of the International Space Station.

Kotov works with samples from the Bioscience Experiment ASEPTIC during Joint Operations

NASA Image and Video Library

2010-02-19

ISS022-E-068645 (18 Feb. 2010) --- Russian cosmonaut Oleg Kotov, Expedition 22 flight engineer, works with samples from the bioscience experiment ASEPTIC (BTKh-39) in the new Russian Glavboks-S (Glovebox) located in the Poisk Mini-Research Module 2 (MRM2) of the International Space Station.

77 FR 59611 - Notice of Receipt of Pesticide Products; Registration Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-28

... Symbol: 85004-RN. Docket ID Number: EPA-HQ-OPP-2012- 0609. Applicant: Pasteuria Bioscience, Inc., 12085 Research Dr., Suite 185, Alachua, FL 32615. Active ingredient: Nematicide with Pasteuria spp. (Hoplolaimus... Symbol: 85004-RR. Docket ID Number: EPA-HQ-OPP-2012- 0609. Applicant: Pasteuria Bioscience, Inc., 12085...

Development of an Electronic Role-Play Assessment Initiative in Bioscience for Nursing Students

ERIC Educational Resources Information Center

Craft, Judy; Ainscough, Louise

2015-01-01

Devising authentic assessments for subjects with large enrolments is a challenge. This study describes an electronic role-play assessment for approximately 600 first-year nursing students to learn and apply pathophysiology (bioscience) concepts to nursing practice. Students used Microsoft Office PowerPoint[R] to prepare electronic role-plays both…

The Current State of Sustainability in Bioscience Laboratories: A Statistical Examination of a UK Tertiary Institute

ERIC Educational Resources Information Center

Wright, Hazel A.; Ironside, Joseph E.; Gwynn-Jones, Dylan

2008-01-01

Purpose: This study aims to identify the current barriers to sustainability in the bioscience laboratory setting and to determine which mechanisms are likely to increase sustainable behaviours in this specialised environment. Design/methodology/approach: The study gathers qualitative data from a sample of laboratory researchers presently…

Design of an Integrated Team Project as Bachelor Thesis in Bioscience Engineering

ERIC Educational Resources Information Center

Peeters, Marie-Christine; Londers, Elsje; Van der Hoeven, Wouter

2014-01-01

Following the decision at the KU Leuven to implement the educational concept of guided independent learning and to encourage students to participate in scientific research, the Faculty of Bioscience Engineering decided to introduce a bachelor thesis. Competencies, such as communication, scientific research and teamwork, need to be present in the…

Challenges in Understanding Photosynthesis in a University Introductory Biosciences Class

ERIC Educational Resources Information Center

Södervik, Ilona; Virtanen, Viivi; Mikkilä-Erdmann, Mirjamaija

2015-01-01

University students' understanding of photosynthesis was examined in a large introductory biosciences class. The focus of this study was to first examine the conceptions of photosynthesis among students in class and then to investigate how a certain type of text could enhance students' understanding of photosynthesis. The study was based on pre-…

New Generation Sequencing Technology Panel at SFAF-Part II

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fiske, Haley; Turner, Steve; Rhodes, Michael

2009-05-27

From left to right: Haley Fiske of Illumina Inc., Steve Turner of Pacific Biosciences, Michael Rhodes of Applied Biosystems, Patrice Milos of Helicos Biosciences and Tim Harkins of Roche Diagnostics answer questions in a forum moderated by Bob Fulton at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM.

New Generation Sequencing Technology Panel at SFAF-Part I

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fiske, Haley; Turner, Steve; Rhodes, Michael

2009-05-27

From left to right: Haley Fiske of Illumina Inc., Steve Turner of Pacific Biosciences, Michael Rhodes of Applied Biosystems, Patrice Milos of Helicos Biosciences and Tim Harkins of Roche Diagnostics answer questions in a forum moderated by Bob Fulton at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM.

Bella's Beetle: Approaching Bioscience Practice from Its Silent Kinaesthetic and Affective Side

ERIC Educational Resources Information Center

Hay, David

2017-01-01

This article critically explores the epistemic "practices" of bioscience, using creative writing and analyses of science studies to implicate the non-linguistic side of science where a "feeling for the organism" matters more, perhaps, than theoretical precision. It offers new critique of curricula in science which are so…

"Novice Teachers" Views of an Introductory Workshop about Teaching in the Biosciences

ERIC Educational Resources Information Center

Gartland, Kevan M. A.; Perkins, Joy; Shearer, Morven C.; Tierney, Anne M.; Wilson, Jackie J.

2013-01-01

Seven regional networking events, aimed at supporting and developing "early stage" novice university bioscience teachers were held across the UK. These workshops allowed 230 participants to reflect on teaching styles, learn about Higher Education Academy resources and discuss strategies to deal with a range of teaching situations.…

Gateway to the Future. Skill Standards for the Bioscience Industry for Technical Workers in Pharmaceutical Companies, Biotechnology Companies, and Clinical Laboratories.

ERIC Educational Resources Information Center

Education Development Center, Inc., Newton, MA.

The Bioscience Industry Skills Standards Project (BISSP) is developing national, voluntary skill standards for technical jobs in biotechnology and pharmaceutical companies and clinical laboratories in hospitals, universities, government, and independent settings. Research with employees and educators has pinpointed three issues underscoring the…

Mechanistic Insights into the Structure-Dependent Selectivity of Catalytic Furfural Conversion on Platinum Catalysts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cai, Qiuxia; Wang, Jianguo; Wang, Yang-Gang

The effects of structure and size on the selectivity of catalytic furfural conversion over supported Pt catalysts in the presence of hydrogen have been studied using first principles density functional theory (DFT) calculations and microkinetic modeling. Four Pt model systems, i.e., periodic Pt(111), Pt(211) surfaces, as well as small nanoclusters (Pt13 and Pt55) are chosen to represent the terrace, step, and corner sites of Pt nanoparticles. Our DFT results show that the reaction routes for furfural hydrogenation and decarbonylation are strongly dependent on the type of reactive sites, which lead to the different selectivity. On the basis of the size-dependentmore » site distribution rule, we correlate the site distributions as a function of the Pt particle size. Our microkinetic results indicate the critical particle size that controls the furfural selectivity is about 1.0 nm, which is in good agreement with the reported experimental value under reaction conditions. This work was supported by National Basic Research Program of China (973 Program) (2013CB733501) and the National Natural Science Foundation of China (NSFC-21306169, 21176221, 21136001, 21101137 and 91334103). This work was also partially supported by the US Department of Energy (DOE), the Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences & Biosciences. Pacific Northwest National Laboratory (PNNL) is a multiprogram national laboratory operated for DOE by Battelle. Computing time was granted by the grand challenge of computational catalysis of the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL). EMSL is a national scientific user facility located at Pacific Northwest National Laboratory (PNNL) and sponsored by DOE’s Office of Biological and Environmental Research.« less

Synergistic Effect of Nitrogen in Cobalt Nitride and Nitrogen-Doped Hollow Carbon Spheres for Oxygen Reduction Reaction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhong, Xing; Liu, Lin; Jiang, Yu

The need for inexpensive and high-activity oxygen reduction reaction (ORR) electrocatalysts has attracted considerable research interest over the past years. Here we report a novel hybrid that contains cobalt nitride/nitrogen-rich hollow carbon spheres (CoxN/NHCS) as a high-performance catalyst for ORR. The CoxN nanoparticles were uniformly dispersed and confined in the hollow NHCS shell. The performance of the resulting CoxN/NHCS hybrid was comparable with that of a commercial Pt/C at the same catalyst loading toward ORR, but the mass activity of the former was 5.7 times better than that of the latter. The nitrogen in both CoxN and NHCS, especially CoxN,more » could weaken the adsorption of reaction intermediates (O and OOH), which follows the favourable reaction pathway on CoxN/NHCS according to the DFT-calculated Gibbs free energy diagrams. Our results demonstrated a new strategy for designing and developing inexpensive, non-precious metal electrocatalysts for next-generation fuels. The authors acknowledge the financial support from the National Basic Research Program (973 program, No. 2013CB733501) and the National Natural Science Foundation of China (No. 21306169, 21101137, 21136001, 21176221 and 91334013). Dr. D. Mei is supported by the US Department of Energy (DOE), Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences & Biosciences. Pacific Northwest National Laboratory (PNNL) is a multiprogram national laboratory operated for DOE by Battelle. Computing time was granted by the grand challenge of computational catalysis of the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL). EMSL is a national scientific user facility located at Pacific Northwest National Laboratory (PNNL) and sponsored by DOE’s Office of Biological and Environmental Research.« less

Production of Doctorates in the Biosciences, 1975-1980: An Experimental Forecast. Higher Education Panel Reports, No. 34.

ERIC Educational Resources Information Center

Atelsek, Frank J.; Gomberg, Irene L.

A survey was undertaken in 1976 to obtain short-term estimates of doctorate production directly from the heads of the science departments involved. These biosciences departments were surveyed in the 235 member institutions of the Higher Education Panel that grant doctorates: anatomy, biochemistry, biology, biometry/biostatistics/biomathematics,…

Assessment of Human Performance in a Simulated Rotorcraft Downwash Environment

DTIC Science & Technology

2007-05-01

Plaga Biosciences and Protection Division Biomechanics Branch May 2007 Final Report for December 2004 to August 2005... Biomechanics Branch Wright-Patterson AFB OH 45433-7947 Approved for public release; distribution is unlimited NOTICE AND SIGNATURE PAGE...Human Effectiveness Directorate Biosciences & Protection Division Biomechanics Branch Wright-Patterson AFB OH 45433-7947 11. SPONSOR/MONITOR’S

Skills and Knowledge Needs among Recent Bioscience Graduates--How Do Our Courses Measure Up?

ERIC Educational Resources Information Center

Brown, Colin A.; Calvert, Jane; Charman, Paul; Newton, Chris; Wiles, Kathy; Hughes, Ian

2005-01-01

A telephone survey was conducted of 2002 or 2003 graduates (942 in total) from various bioscience degree programmes at 4 universities. A structured and scripted interview determined: title/class of degree; nature of current occupation (unemployed, further degree, job) and if regarded as "career related" post or just "filling in"; if current…

Effect of A-Level Subject Choice and Entry Tariff on Final Degree and Level 1 Performance in Biosciences

ERIC Educational Resources Information Center

King, Nicola C.; Aves, Stephen J.

2012-01-01

Following the publication of the higher education white paper increasing entry tariff and widening participation have become even more important issues for universities. This report examines the relationship between entry tariff and undergraduate achievement in Biosciences at the University of Exeter. We show that, whilst there is a significant…

"Biomathtutor": Evaluation of a New Multimedia E-Learning Resource to Support Mathematics in the Biosciences

ERIC Educational Resources Information Center

Tariq, V. N.; Jackson, V.

2008-01-01

The objective of this study was to evaluate "biomathtutor" by (i) investigating the impact of "biomathtutor" on the mathematics skills competencies of bioscience undergraduates, and (ii) assessing students' and tutors' reactions to "biomathtutor", identifying whether and how tutors might integrate it into their curricula and blend it with more…

78 FR 27468 - Order of Suspension of Trading in the Matter of CoreCare Systems, Inc., Forticell Bioscience, Inc...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-10

... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] Order of Suspension of Trading in the Matter of CoreCare Systems, Inc., Forticell Bioscience, Inc., Michelex Corporation, and Rx for Africa, Inc... accurate information concerning the securities of CoreCare Systems, Inc. because it has not filed any...

Students' and Teacher's Experiences of the Validity and Reliability of Assessment in a Bioscience Course

ERIC Educational Resources Information Center

Räisänen, Milla; Tuononen, Tarja; Postareff, Liisa; Hailikari, Telle; Virtanen, Viivi

2016-01-01

This case study explores the assessment of students' learning outcomes in a second-year lecture course in biosciences. The aim is to deeply explore the teacher's and the students' experiences of the validity and reliability of assessment and to compare those perspectives. The data were collected through stimulated recall interviews. The results…

Toward interoperable bioscience data

PubMed Central

Sansone, Susanna-Assunta; Rocca-Serra, Philippe; Field, Dawn; Maguire, Eamonn; Taylor, Chris; Hofmann, Oliver; Fang, Hong; Neumann, Steffen; Tong, Weida; Amaral-Zettler, Linda; Begley, Kimberly; Booth, Tim; Bougueleret, Lydie; Burns, Gully; Chapman, Brad; Clark, Tim; Coleman, Lee-Ann; Copeland, Jay; Das, Sudeshna; de Daruvar, Antoine; de Matos, Paula; Dix, Ian; Edmunds, Scott; Evelo, Chris T; Forster, Mark J; Gaudet, Pascale; Gilbert, Jack; Goble, Carole; Griffin, Julian L; Jacob, Daniel; Kleinjans, Jos; Harland, Lee; Haug, Kenneth; Hermjakob, Henning; Ho Sui, Shannan J; Laederach, Alain; Liang, Shaoguang; Marshall, Stephen; McGrath, Annette; Merrill, Emily; Reilly, Dorothy; Roux, Magali; Shamu, Caroline E; Shang, Catherine A; Steinbeck, Christoph; Trefethen, Anne; Williams-Jones, Bryn; Wolstencroft, Katherine; Xenarios, Ioannis; Hide, Winston

2012-01-01

To make full use of research data, the bioscience community needs to adopt technologies and reward mechanisms that support interoperability and promote the growth of an open ‘data commoning’ culture. Here we describe the prerequisites for data commoning and present an established and growing ecosystem of solutions using the shared ‘Investigation-Study-Assay’ framework to support that vision. PMID:22281772

Mathematic in science progress reort, June 1, 1973-May 31, 1974

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bellman, R.

1974-01-01

The purpose of the matematical biosciences group is to use the conceptual, analytic and computational methods of modern mathematics to treat biomedical and environmental problems. We are employing a systems approach to research, beginning with experiment and medical practice at one end of the scale, continuing through the intermediary of mathematical models and computer techniques, and culminating in clinical applications working closely with teams of doctors. We are pursuing the application of biostatistical methods to a number of medical questions as well as a thoroughgoing use of operations research and systems analysis to hospital practice. The overall objective is tomore » make the Medicare program operational, effective as well as cheap. Pattern recognition and other aspects of artificial intelligence are important here for patient screening. Major efforts are devoted to nuclear medicine, radiotherapy and neurophysiology using the mathematical theory of control and decision processes (dynamic programming and invarient imbedding). Important savings have been made in the time required for tumor scanning using techniques of nuclear medicine. Major mathematical breakthroughs have been made in the treatment of large scale systems, and parameter identification processes. In the field of mental health, we have developed and extended the computerized simulation processes using graphics which are versatile tools for research and training in human interaction processes, particularly in the initial psychotherapy interview.« less

Developing library bioinformatics services in context: the Purdue University Libraries bioinformationist program

PubMed Central

Rein, Diane C.

2006-01-01

Setting: Purdue University is a major agricultural, engineering, biomedical, and applied life science research institution with an increasing focus on bioinformatics research that spans multiple disciplines and campus academic units. The Purdue University Libraries (PUL) hired a molecular biosciences specialist to discover, engage, and support bioinformatics needs across the campus. Program Components: After an extended period of information needs assessment and environmental scanning, the specialist developed a week of focused bioinformatics instruction (Bioinformatics Week) to launch system-wide, library-based bioinformatics services. Evaluation Mechanisms: The specialist employed a two-tiered approach to assess user information requirements and expectations. The first phase involved careful observation and collection of information needs in-context throughout the campus, attending laboratory meetings, interviewing department chairs and individual researchers, and engaging in strategic planning efforts. Based on the information gathered during the integration phase, several survey instruments were developed to facilitate more critical user assessment and the recovery of quantifiable data prior to planning. Next Steps/Future Directions: Given information gathered while working with clients and through formal needs assessments, as well as the success of instructional approaches used in Bioinformatics Week, the specialist is developing bioinformatics support services for the Purdue community. The specialist is also engaged in training PUL faculty librarians in bioinformatics to provide a sustaining culture of library-based bioinformatics support and understanding of Purdue's bioinformatics-related decision and policy making. PMID:16888666

A Radar-like Iron based Nanohybrid as an Efficient and Stable Electrocatalyst for Oxygen Reduction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhong, X. Y.; Liu, Lin; Wang, Xinde

2014-05-21

The present study shows a design concept for fabricating Fe-PyNG hybrid via strong coupling between FePc and pyridine-N. The prominent features of the Fe-PyNG hybrid include high electrocatalytic activity, superior durability, and better performance than Pt/C toward ORR in alkaline media. These features potentially make Fe-PyNG an outstanding nonprecious metal cathode catalyst for fuel cells. The incorporation of Fe ion and pyridine-N afforded effective bonding and synergetic coupling effects, which lead to significant electrocatalytic performance. DFT calculations indicate that N-modified Fe is a superior site for OOH adsorption and ORR reaction. Meanwhile, the strong chemical bonding between FePc and pyridynemore » in PyNG leads to its superior stability. We believe that our present synthetic strategy can be further extended to develop other metal complexes/N-doped carbon materials for broad applications in the field of catalysts, batteries, and supercapacitors. This work was supported by National Basic Research Program of China (973 Program) (2013CB733501), the National Natural Science Foundation of China (NSFC-21306169, 21176221, 21136001 and 21101137), Zhejiang Provincial Natural Science Foundation of China (ZJNSF-R4110345) and the New Century Excellent Talents in University Program (NCET-10-0979). We thank Prof. Youqun Zhu for Instruments support. D. Mei is supported by the US Department of Energy, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences & Biosciences. Pacific Northwest National Laboratory (PNNL) is a multiprogram national laboratory operated for DOE by Battelle. Computing time was granted by the grand challenge of computational catalysis of the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL). EMSL is a national scientific user facility located at Pacific Northwest National Laboratory (PNNL) and sponsored by DOE’s Office of Biological and Environmental Research.« less

LANL continuity of operations plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Senutovitch, Diane M

2010-12-22

The Los Alamos National Laboratory (LANL) is a premier national security research institution, delivering scientific and engineering solutions for the nation's most crucial and complex problems. Our primary responsibility is to ensure the safety, security, and reliability of the nation's nuclear stockpile. LANL emphasizes worker safety, effective operational safeguards and security, and environmental stewardship, outstanding science remains the foundation of work at the Laboratory. In addition to supporting the Laboratory's core national security mission, our work advances bioscience, chemistry, computer science, earth and environmental sciences, materials science, and physics disciplines. To accomplish LANL's mission, we must ensure that the Laboratorymore » EFs continue to be performed during a continuity event, including localized acts of nature, accidents, technological or attack-related emergencies, and pandemic or epidemic events. The LANL Continuity of Operations (COOP) Plan documents the overall LANL COOP Program and provides the operational framework to implement continuity policies, requirements, and responsibilities at LANL, as required by DOE 0 150.1, Continuity Programs, May 2008. LANL must maintain its ability to perform the nation's PMEFs, which are: (1) maintain the safety and security of nuclear materials in the DOE Complex at fixed sites and in transit; (2) respond to a nuclear incident, both domestically and internationally, caused by terrorist activity, natural disaster, or accident, including mobilizing the resources to support these efforts; and (3) support the nation's energy infrastructure. This plan supports Continuity of Operations for Los Alamos National Laboratory (LANL). This plan issues LANL policy as directed by the DOE 0 150.1, Continuity Programs, and provides direction for the orderly continuation of LANL EFs for 30 days of closure or 60 days for a pandemic/epidemic event. Initiation of COOP operations may be required to support an allhazards event, including a national security emergency, major fire, catastrophic natural disaster, man-made disaster, terrorism event, or technological disaster by rendering LANL buildings, infrastructure, or Technical Areas unsafe, temporarily unusable, or inaccessible.« less

Comparative epigenetics: relevance to the regulation of production and health traits in cattle.

PubMed

Doherty, Rachael; O' Farrelly, Cliona; Meade, Kieran G

2014-08-01

With the development of genomic, transcriptomic and bioinformatic tools, recent advances in molecular technologies have significantly impacted bovine bioscience research and are revolutionising animal selection and breeding. Integration of epigenetic information represents yet another challenging molecular frontier. Epigenetics is the study of biochemical modifications to DNA and to histones, the proteins that provide stability to DNA. These epigenetic changes are induced by environmental stimuli; they alter gene expression and are potentially heritable. Epigenetics research holds the key to understanding how environmental factors contribute to phenotypic variation in traits of economic importance in cattle including development, nutrition, behaviour and health. In this review, we discuss the potential applications of epigenetics in bovine research, using breakthroughs in human and murine research to signpost the way. © 2014 Stichting International Foundation for Animal Genetics.

Importance of Peer Support and Tutor Involvement in Entrepreneurship Education for Overseas Bioscience Students

ERIC Educational Resources Information Center

Mitchell, P. C.; McKeown, A. E.

2004-01-01

An increasing number of Bioscience courses embed entrepreneurship learning outcomes within the curriculum, across a number of modules and/or within a dedicated module. The level 2, Developing People and Products module is one such example, involving students in 100 study effort hours over 7 weeks. This module was delivered to students (n = 37)…

The Role of the Postgraduate Student in Delivering Bioscience Teaching

ERIC Educational Resources Information Center

Scott, Jon; Maw, Stephen J.

2009-01-01

There has been much recent interest in the extent to which the teaching in higher education delivered by non-academic staff has increased in the recent past. Within the Biosciences there has always been a tradition of engaging postgraduate students to support the delivery of some forms of teaching. In this paper we report on the findings of a…

The Use of Team-Based, Guided Inquiry Learning to Overcome Educational Disadvantages in Learning Human Physiology: A Structural Equation Model

ERIC Educational Resources Information Center

Rathner, Joseph A.; Byrne, Graeme

2014-01-01

The study of human bioscience is viewed as a crucial curriculum in allied health. Nevertheless, bioscience (and particularly physiology) is notoriously difficult for undergraduates, particularly academically disadvantaged students. So endemic are the high failure rates (particularly in nursing) that it has come to be known as "the human…

Analysis of a Phase 2b Study of GEN-003, a Genital Herpes Immunotherapy, Showed Significant Reductions in Viral Shedding and Lesion Rate Vs Placebo

PubMed Central

Heineman, Thomas C; Bernstein, David; Wald, Anna; Van Wagoner, Nicholas; Leone, Peter; Mayer, Kenneth; Lucksinger, Gregg; Win, Sandra; Koltun, William; Desai, Nisha; Oliphant, Thomas; Natenshon, Andrew; McNeil, Lisa K; Flechtner, Jessica B; Hetherington, Seth

2017-01-01

Abstract Background GEN-003 is an investigational genital herpes immunotherapy comprising gD2ΔTMR, an HSV-2 antigen that induces neutralizing antibody and T cell responses, ICP4.2, an HSV-2 T cell antigen selected through human T cell screens, and Matrix-M2™, a saponin-based adjuvant. This Phase 2b study was designed to evaluate efficacy and safety of GEN-003 vs. placebo. Methods Healthy persons, age 18–50 years, with 3–9 HSV-2 genital herpes outbreaks annually were randomized to 3 groups: placebo, or 60 µg of each antigen combined with 50 µg (60/50 group) or 75 µg (60/75 group) of adjuvant, administered 3 times 21 days apart. Study endpoints included safety, immunogenicity, HSV-2 shedding frequency, lesion rate and recurrence frequency. Viral shedding was measured from anogenital swabs by PCR. Swabs were collected for 28 days at baseline, and after the third dose, 6 months and 1 year. The presence of herpes lesions was recorded daily by electronic diary. Results One hundred and thirty-one participants enrolled and >90% received all 3 doses. In the 28-day post-treatment period, viral shedding was reduced by 40% and 27% in the 60/50 and 60/75 groups, respectively, compared with a 5% increase in the placebo group. At 6 months post-treatment, median lesion rates were significantly lower in the 60/50 and 60/75 groups (2.7% and 1.9%, respectively) vs. the placebo group (5.6%, p < 0.05), resulting in median reductions of 52% and 66%. In participants not receiving suppressive antivirals, the median recurrence frequency was 1.0/6 months in the 60/50 group vs. 2.0 in the placebo group (p = 0.08). The median recurrence duration in the 60/50 group was lower than in the placebo group (2.8 vs. 4.2 days; p < 0.05). The most commonly reported adverse events (AEs) following GEN-003 vaccination were injection site pain/tenderness (97%), fatigue (82%), headache (82%) and myalgia (80%). No vaccine-related serious AEs, autoimmune events or other AEs of special interest were reported. Conclusion In adults with recurrent genital herpes, GEN-003 reduced HSV-2 shedding frequency, genital herpes lesion rate, recurrence frequency and recurrence duration through 6 months after the last dose. Local and systemic symptoms were common in GEN-003 recipients, but treatment completion was high with few discontinuations due to AEs. Disclosures T. C. Heineman, GSK group of companies: Consultant and Shareholder, Consulting fee; D. Bernstein, Genocea Biosciences: Consultant and Investigator, Consulting fee and Research support; A. Wald, Genocea Biosciences: Investigator, Research grant and Support for travel to meetings for the study; N. Van Wagoner, Genocea Biosciences: Consultant, Research support and Travel support to present at scientific meetings; P. Leone, Genocea Biosciences: Grant Investigator and Scientific Advisor, Consulting fee, Research grant and Speaker honorarium; 
T. Oliphant, Genocea Biosciences: Consultant, Consulting fee; A. Natenshon, Genocea Biosciences: Employee, Salary; L. K. McNeil, Genocea Biosciences: Employee, Salary; J. B. Flechtner, Genocea Biosciences: Employee, Salary; S. Hetherington, Genocea Biosciences: Employee, Salary

Laboratory-directed research and development: FY 1996 progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vigil, J.; Prono, J.

1997-05-01

This report summarizes the FY 1996 goals and accomplishments of Laboratory-Directed Research and Development (LDRD) projects. It gives an overview of the LDRD program, summarizes work done on individual research projects, and provides an index to the projects` principal investigators. Projects are grouped by their LDRD component: Individual Projects, Competency Development, and Program Development. Within each component, they are further divided into nine technical disciplines: (1) materials science, (2) engineering and base technologies, (3) plasmas, fluids, and particle beams, (4) chemistry, (5) mathematics and computational sciences, (6) atomic and molecular physics, (7) geoscience, space science, and astrophysics, (8) nuclear andmore » particle physics, and (9) biosciences.« less

Laboratory Directed Research and Development Program FY 2008 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

editor, Todd C Hansen

2009-02-23

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operatemore » unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2008 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD program supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under consideration and review by the Office of Science Program Offices, such as LDRD projects germane to new research facility concepts and new fundamental science directions. Berkeley Lab LDRD program also play an important role in leveraging DOE capabilities for national needs. The fundamental scientific research and development conducted in the program advances the skills and technologies of importance to our Work For Others (WFO) sponsors. Among many directions, these include a broad range of health-related science and technology of interest to the National Institutes of Health, breast cancer and accelerator research supported by the Department of Defense, detector technologies that should be useful to the Department of Homeland Security, and particle detection that will be valuable to the Environmental Protection Agency. The Berkeley Lab Laboratory Directed Research and Development Program FY2008 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the supported projects and summarizes their accomplishments. It constitutes a part of the LDRD program planning and documentation process that includes an annual planning cycle, project selection, implementation, and review.« less

Static and Dynamic Human Shape Modeling - A Review of the Literature and State of the Art

DTIC Science & Technology

2009-04-01

Figure 60. Confluent marker-based animation (Aguiar et al. 2006). Subsequent frames showing the female scan authentically performing a soccer kick ...Infoscitex Corp. 4027 Colonel Glenn Highway Suite 210 Dayton OH 45431-1672 Kathleen Robinette Biosciences and Protection Division Biomechanics ...Biosciences and Protection Division Biomechanics Branch Wright-Patterson AFB OH 45433 Approved for public release; distribution unlimited. NOTICE

Attitudes to Teaching Ethics to Bioscience Students: An Interview-Based Study Comparing British and American University Teachers

ERIC Educational Resources Information Center

Bryant, John A.; Morgan, Cindy L.

2007-01-01

An interview-based survey was carried out with British and American university teachers. In both countries there was widespread (but in the UK, not unanimous) support for the proposition that ethics should be taught to Bioscience students. Reasons included a need to help students engage with the ethical issues associated with their subject and the…

A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers.

PubMed

Quail, Michael A; Smith, Miriam; Coupland, Paul; Otto, Thomas D; Harris, Simon R; Connor, Thomas R; Bertoni, Anna; Swerdlow, Harold P; Gu, Yong

2012-07-24

Next generation sequencing (NGS) technology has revolutionized genomic and genetic research. The pace of change in this area is rapid with three major new sequencing platforms having been released in 2011: Ion Torrent's PGM, Pacific Biosciences' RS and the Illumina MiSeq. Here we compare the results obtained with those platforms to the performance of the Illumina HiSeq, the current market leader. In order to compare these platforms, and get sufficient coverage depth to allow meaningful analysis, we have sequenced a set of 4 microbial genomes with mean GC content ranging from 19.3 to 67.7%. Together, these represent a comprehensive range of genome content. Here we report our analysis of that sequence data in terms of coverage distribution, bias, GC distribution, variant detection and accuracy. Sequence generated by Ion Torrent, MiSeq and Pacific Biosciences technologies displays near perfect coverage behaviour on GC-rich, neutral and moderately AT-rich genomes, but a profound bias was observed upon sequencing the extremely AT-rich genome of Plasmodium falciparum on the PGM, resulting in no coverage for approximately 30% of the genome. We analysed the ability to call variants from each platform and found that we could call slightly more variants from Ion Torrent data compared to MiSeq data, but at the expense of a higher false positive rate. Variant calling from Pacific Biosciences data was possible but higher coverage depth was required. Context specific errors were observed in both PGM and MiSeq data, but not in that from the Pacific Biosciences platform. All three fast turnaround sequencers evaluated here were able to generate usable sequence. However there are key differences between the quality of that data and the applications it will support.

Has bioscience reconciled mind and body?

PubMed

Davies, Carmel; Redmond, Catherine; Toole, Sinead O; Coughlan, Barbara

2016-09-01

The aim of this discursive paper is to explore the question 'has biological science reconciled mind and body?'. This paper has been inspired by the recognition that bioscience has a historical reputation for privileging the body over the mind. The disregard for the mind (emotions and behaviour) cast bioscience within a 'mind-body problem' paradigm. It has also led to inherent limitations in its capacity to contribute to understanding the complex nature of health. This is a discursive paper. Literature from the history and sociology of science and psychoneuroimmunology (1975-2015) inform the arguments in this paper. The historical and sociological literature provides the basis for a socio-cultural debate on mind-body considerations in science since the 1970s. The psychoneuroimmunology literature draws on mind-body bioscientific theory as a way to demonstrate how science is reconciling mind and body and advancing its understanding of the interconnections between emotions, behaviour and health. Using sociological and biological evidence, this paper demonstrates how bioscience is embracing and advancing its understanding of mind-body interconnectedness. It does this by demonstrating the emotional and behavioural alterations that are caused by two common phenomena; prolonged, chronic peripheral inflammation and prolonged psychological stress. The evidence and arguments provided has global currency that advances understanding of the inter-relationship between emotions, behaviour and health. This paper shows how bioscience has reconciled mind and body. In doing so, it has advanced an understanding of science's contribution to the inter-relationship between emotions, behaviour and health. The biological evidence supporting mind-body science has relevance to clinical practice for nurses and other healthcare professions. This paper discusses how this evidence can inform and enhance clinical practice directly and through research, education and policy. © 2015 John Wiley & Sons Ltd.

Biomedical wellness challenges and opportunities

NASA Astrophysics Data System (ADS)

Tangney, John F.

2012-06-01

The mission of ONR's Human and Bioengineered Systems Division is to direct, plan, foster, and encourage Science and Technology in cognitive science, computational neuroscience, bioscience and bio-mimetic technology, social/organizational science, training, human factors, and decision making as related to future Naval needs. This paper highlights current programs that contribute to future biomedical wellness needs in context of humanitarian assistance and disaster relief. ONR supports fundamental research and related technology demonstrations in several related areas, including biometrics and human activity recognition; cognitive sciences; computational neurosciences and bio-robotics; human factors, organizational design and decision research; social, cultural and behavioral modeling; and training, education and human performance. In context of a possible future with automated casualty evacuation, elements of current science and technology programs are illustrated.

Quantitative skills as a graduate learning outcome of university science degree programmes: student performance explored through theplanned-enacted-experiencedcurriculum model

NASA Astrophysics Data System (ADS)

Matthews, Kelly E.; Adams, Peter; Goos, Merrilyn

2016-07-01

Application of mathematical and statistical thinking and reasoning, typically referred to as quantitative skills, is essential for university bioscience students. First, this study developed an assessment task intended to gauge graduating students' quantitative skills. The Quantitative Skills Assessment of Science Students (QSASS) was the result, which examined 10 mathematical and statistical sub-topics. Second, the study established an evidential baseline of students' quantitative skills performance and confidence levels by piloting the QSASS with 187 final-year biosciences students at a research-intensive university. The study is framed within the planned-enacted-experienced curriculum model and contributes to science reform efforts focused on enhancing the quantitative skills of university graduates, particularly in the biosciences. The results found, on average, weak performance and low confidence on the QSASS, suggesting divergence between academics' intentions and students' experiences of learning quantitative skills. Implications for curriculum design and future studies are discussed.

Numerical modelling in biosciences using delay differential equations

NASA Astrophysics Data System (ADS)

Bocharov, Gennadii A.; Rihan, Fathalla A.

2000-12-01

Our principal purposes here are (i) to consider, from the perspective of applied mathematics, models of phenomena in the biosciences that are based on delay differential equations and for which numerical approaches are a major tool in understanding their dynamics, (ii) to review the application of numerical techniques to investigate these models. We show that there are prima facie reasons for using such models: (i) they have a richer mathematical framework (compared with ordinary differential equations) for the analysis of biosystem dynamics, (ii) they display better consistency with the nature of certain biological processes and predictive results. We analyze both the qualitative and quantitative role that delays play in basic time-lag models proposed in population dynamics, epidemiology, physiology, immunology, neural networks and cell kinetics. We then indicate suitable computational techniques for the numerical treatment of mathematical problems emerging in the biosciences, comparing them with those implemented by the bio-modellers.

Developing Research Capabilities in Energy Biosciences

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Donald D.

2008-01-01

Scientists founded the Life Sciences Research Foundation (LSRF) in 1983 as a non-profit pass through foundation that awards post doctoral fellowships in all areas of the life sciences. LSRF scientists review hundreds of applications each year from PhDs seeking support. For example this year, our 26th, we received 800 applications and our peer review committee will choose about 50 finalists who are eligible for these awards. We have no endowment so we solicit sponsors each year. The fellowships are sponsored by research oriented companies, foundations, philanthropists, the Howard Hughes Medical Institute, and other organizations who believe in the value ofmore » awarding fellowships to the best and the brightest young scientists. Our web site has a complete listing of all details about LSRF (http://www.lsrf.org/). In the late 1980s the Division of Bioscience in the Office of Basic Energy Science, a granting agency of the Department of Energy, joined this partnership. Bioscience's mandate was to support non-medical microbiology and plant sciences. LSRF received a series of 5 year grants from DOE to award fellowships to our top applicants in these fields of research. We began to support DOE-Energy Bioscience post doctoral fellows in 1989. From 1989 through 2004 when DOE funding ended our partnership awarded 41 DOE-Energy Bioscience Fellows of the Life Sciences Research Foundation. Each of these was a three year fellowship. DOE-Energy Biosciences was well matched with LSRF. Our extensive peer review screened applicants in all areas of the life sciences. Most LSRF sponsors are interested in supporting fellows who work on diseases. At the time that we began our partnership with DOE we had no sponsors willing to support plant biology and non medical microbiology. For 15 years DOE played a major role in the training of the very best young scientists in these important fields of research simply through its support of LSRF post doctoral fellows. Young scientists interested in plant biology knew to apply to LSRF for a chance to receive a post doctoral award. We are enclosing a list of the 41 fellows who were supported through this partnership. The list includes some of the most distinguished plant biologists in the country, and our training partnership has had a profound impact on the field of plant biology.« less

12th Annual ALS Users' Association Meeting

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robinson, Arthur L.

1999-12-17

Science took the front seat as 219 Advanced Light Source (ALS) users and staff gathered on Monday and Tuesday, October 18 and 19 for the twelfth annual users' meeting. The bulk of the meeting was dedicated to reports on science at the ALS. Packed into two busy days were 31 invited oral presentations and 80 submitted poster presentations, as well as time to visit 24 vendor booths. The oral sessions were dedicated to environmental science, chemical dynamics, biosciences, magnetic materials, and atomic and molecular science. In addition, there was an ALS highlights session that emphasized new results and a sessionmore » comprising highlights from the young scientists who will carry the ALS into the future.« less

Evaluation of Evidence for Altered Behavior and Auditory Deficits in Fishes Due to Human-Generated Noise Sources

DTIC Science & Technology

2006-04-01

prepared by the Research and Animal Care Branch, Code 2351, of the Biosciences Division, Code 235, SSC San Diego. This is a work of the United...and Animal Care Branch Under authority of M. Rothe, Head Biosciences Division i EXECUTIVE SUMMARY In this study, we have evaluated peer... sharks , skates, and rays) and teleost fishes (modern bony fishes) and provide recommendations for research to address remaining issues. Clear responses

In Situ Fabrication of PtCo Alloy Embedded in Nitrogen-Doped Graphene Nanopores as Synergistic Catalyst for Oxygen Reduction Reaction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhong, Xing; Wang, Lei; Zhou, Hu

A novel PtCo alloy in situ etched and embedded in graphene nanopores (PtCo/NPG) as a high-performance catalyst for ORR was reported. Graphene nanopores were fabricated in situ while forming PtCo nanoparticles that were uniformly embedded in the graphene nanopores. Given the synergistic effect between PtCo alloy and nanopores, PtCo/NPG exhibited 11.5 times higher mass activity than that of the commercial Pt/C cathode electrocatalyst. DFT calculations indicated that the nanopores in NPG cannot only stabilize PtCo nanoparticles but can also definitely change the electronic structures, thereby change its adsorption abilities. This enhancement can lead to a favorable reaction pathway on PtCo/NPGmore » for ORR. This study showed that PtCo/NPG is a potential candidate for the next generation of Pt-based catalysts in fuel cells. This study also offered a promising alternative strategy and enabled the fabrication of various kinds of metal/graphene nanopore nanohybrids with potential applications in catalysts and potential use for other technological devices. The authors acknowledge the financial support from the National Basic Research Program (973 program, No. 2013CB733501), Zhejiang Provincial Education Department Research Program (Y201326554) and the National Natural Science Foundation of China (No. 21306169, 21101137, 21136001, 21176221 and 91334013). D. Mei acknowledges the support from the US Department of Energy, Office of Science, Office of Basic Energy Sciences, Division of Division of Chemical Sciences, Geosciences & Biosciences. Pacific Northwest National Laboratory (PNNL) is a multiprogram national laboratory operated for DOE by Battelle. Computing time was granted by the grand challenge of computational catalysis of the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) and by the National Energy Research Scientific Computing Center (NERSC).« less

The future of graduate and postdoctoral training in the biosciences.

PubMed

Hitchcock, Peter; Mathur, Ambika; Bennett, Jabbar; Cameron, Patricia; Chow, Christine; Clifford, Philip; Duvoisin, Robert; Feig, Andrew; Finneran, Kevin; Klotz, Diane M; McGee, Richard; O'Riordan, Mary; Pfund, Christine; Pickett, Christopher; Schwartz, Nancy; Street, Nancy E; Watkins, Elizabeth; Wiest, Jonathan; Engelke, David

2017-10-19

This article summarizes the outcomes of the second national conference on the Future of Bioscience Graduate and Postdoctoral Training. Five topics were addressed during the conference: diversity in leadership positions; mentoring; modernizing the curriculum; experiential learning; and the need for better data on trainees. The goal of the conference was to develop a consensus around these five topics and to recommend policies that can be implemented by academic and research institutions and federal funding agencies in the United States.

Inkjet Gene Printing: A Novel Approach to Achieve Gene Modified Cells for Tissue Engineering

DTIC Science & Technology

2008-12-01

and pIRES-VEGF-GFP (BD Biosciences, Bedford, MA) encoding the cDNAs of jellyfish Aequorea victoria green fluorescent protein, driven by the...prepared from rat-tail Type I collagen gels using a previously reported protocol(Xu et al. 2005). Briefly, rat- tail Type I collagen (BD Biosciences...aliquots of the mixture were dispersed onto coverslips and cured in an incubator for 3–5 h. Once the gel set, the collagen bio-paper was ready for

The future of graduate and postdoctoral training in the biosciences

PubMed Central

Bennett, Jabbar; Cameron, Patricia; Chow, Christine; Clifford, Philip; Duvoisin, Robert; Feig, Andrew; Finneran, Kevin; Klotz, Diane M; McGee, Richard; O'Riordan, Mary; Pfund, Christine; Pickett, Christopher; Schwartz, Nancy; Street, Nancy E; Watkins, Elizabeth; Wiest, Jonathan; Engelke, David

2017-01-01

This article summarizes the outcomes of the second national conference on the Future of Bioscience Graduate and Postdoctoral Training. Five topics were addressed during the conference: diversity in leadership positions; mentoring; modernizing the curriculum; experiential learning; and the need for better data on trainees. The goal of the conference was to develop a consensus around these five topics and to recommend policies that can be implemented by academic and research institutions and federal funding agencies in the United States. PMID:29049023

Hemostatic Function of Apheresis Platelets Stored at 4 deg C and 22 deg C

DTIC Science & Technology

2014-05-01

utilized. Thromboxane B2 (TxB2) enzyme immunoassay kits were purchased from Cayman Chemicals (Ann Arbor, MI), and human soluble CD40L (sCD40L) extra...sensitive platinum enzyme linked immunosorbent assay kits were pur chased from eBioscience (Vienna, Austria). CG4+ and CHEM8+ cartridges were purchased from...TruCount tubes (BD Biosciences). Enzyme linked immunosorbent assay Commercially available kits were used to assess sCD40L and TxB2 levels released into

Research and technology

NASA Technical Reports Server (NTRS)

1990-01-01

As the NASA center responsible for assembly, checkout, servicing, launch, recovery, and operational support of Space Transportation System elements and payloads, Kennedy Space Center (KSC) is placing increasing emphasis on KSC's research and technology program. In addition to strengthening those areas of engineering and operations technology that contribute to safer, more efficient, and more economical execution of the current mission, the technological tools needed to execute KSC's mission relative to future programs are being developed. The Engineering Development Directorate encompasses most of the laboratories and other KSC resources that are key elements of research and technology program implementation and is responsible for implementation of the majority of the projects in this KSC 1990 annual report. Projects under the following topics are covered: (1) materials science; (2) hazardous emissions and contamination monitoring; (3) biosciences; (4) autonomous systems; (5) communications and control; (6) meteorology; (7) technology utilization; and (8) mechanics, structures, and cryogenics.

Laboratory Directed Research and Development FY2010 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jackson, K J

2011-03-22

A premier applied-science laboratory, Lawrence Livermore National Laboratory (LLNL) has at its core a primary national security mission - to ensure the safety, security, and reliability of the nation's nuclear weapons stockpile without nuclear testing, and to prevent and counter the spread and use of weapons of mass destruction: nuclear, chemical, and biological. The Laboratory uses the scientific and engineering expertise and facilities developed for its primary mission to pursue advanced technologies to meet other important national security needs - homeland defense, military operations, and missile defense, for example - that evolve in response to emerging threats. For broader nationalmore » needs, LLNL executes programs in energy security, climate change and long-term energy needs, environmental assessment and management, bioscience and technology to improve human health, and for breakthroughs in fundamental science and technology. With this multidisciplinary expertise, the Laboratory serves as a science and technology resource to the U.S. government and as a partner with industry and academia. This annual report discusses the following topics: (1) Advanced Sensors and Instrumentation; (2) Biological Sciences; (3) Chemistry; (4) Earth and Space Sciences; (5) Energy Supply and Use; (6) Engineering and Manufacturing Processes; (7) Materials Science and Technology; Mathematics and Computing Science; (8) Nuclear Science and Engineering; and (9) Physics.« less

Space Research Fortifies Nutrition Worldwide

NASA Technical Reports Server (NTRS)

2008-01-01

NASA's Controlled Ecological Life Support Systems program attempted to address basic needs of crews, meet stringent payload and power usage restrictions, and minimize space occupancy, by developing living, regenerative ecosystems that would take care of themselves and their inhabitants. An experiment from this program evolved into one of the most widespread NASA spinoffs of all time-a method for manufacturing an algae-based food supplement that provides the nutrients previously only available in breast milk. Martek Biosciences Corporation, in Columbia, Maryland, now manufactures this supplement, and it can be found in over 90 percent of the infant formulas sold in the United States, as well as those sold in over 65 other countries. With such widespread use, the company estimates that over 24 million babies worldwide have consumed its nutritional additives.

A new fluorescent probe for distinguishing Zn2+ and Cd2+ with high sensitivity and selectivity.

PubMed

Tan, Yiqun; Gao, Junkuo; Yu, Jiancan; Wang, Ziqi; Cui, Yuanjing; Yang, Yu; Qian, Guodong

2013-08-28

A new fluorescence probe for distinguishing Zn(2+) and Cd(2+) is designed and synthesized. For the first time to our knowledge, this probe can recognize similar metal ions by coherently utilizing intramolecular charge transfer (ICT) and different electronic affinities of various metal ions, instead of by selective coordination alone, which may be interfered with and lose its selectivity easily in a complicated environment, providing a distinct recognition even by the naked eye for Zn(2+) and Cd(2+) with the sensitivity at the ppb level. This design strategy may initiate a straightforward approach for the selective detection of various metal ions with similar chemical properties in extensive applications such as environmental, industrial, and bio-science.

Reducing Our Carbon Footprint: Converting Plants to Fuel (LBNL Science at the Theater)

ScienceCinema

Somerville, Chris [Univ. of California, Berkeley, CA (United States)

2018-05-23

Berkeley Lab's Chris Somerville is a leading authority on the structure and function of plant cell walls, which comprise most of the body mass of higher plants. He views the knowledge of cell wall structure and function as furthering the development of plants with improved usefulness: these plants are strong potential sources of renewable materials and biofuel feedstocks. His scientific expertise defines an ideal match of his interest - in the development of cellulosic and other solar-to-fuel science - with his recent appointment as Director of the Energy Biosciences Institute (EBI). With colleagues in biology, physical sciences, engineering, and environmental and the social sciences, he now leads the EBI multidisciplinary teams' research efforts to develop next-generation, carbon-neutral transportation fuels.

State of Supported Nickel Nanoparticles during Catalysis in Aqueous Media

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chase, Zizwe; Kasakov, Stanislav; Shi, Hui

2015-11-09

The state of Ni supported on HZSM-5 zeolite, silica, and sulfonated carbon was determined during aqueous phase catalysis of phenol hydrodeoxygenation using in situ extended X-ray absorption fine structure spectroscopy (EXAFS). On sulfonated carbon and HZSM-5 supports, the NiO and Ni(OH)2 were readily reduced to Ni(0) under reaction conditions (~35 bar H2 in aqueous phenol solutions containing up to 0.5 wt. % phosphoric acid at 473 K). On the silica support, less than 70% of the Ni was converted to Ni(0) under reaction conditions, which is attributed to the formation of Ni phyllosilicates. Over a broad range of reaction conditionsmore » there was no leaching of Ni from the supports. In contrast, rapid leaching of the Ni(II) from HZSM-5 was observed, when 15 wt. % aqueous acetic acid was substituted for the aqueous phenol solution. Once the metallic state of Ni was established there was no leaching in 15 wt. % acetic acid at 473 K and 35 bar H2. This work was supported by the U.S. Department of Energy (DOE), Office of Science, Office of Basic Energy Sciences (BES), Division of Chemical Sciences, Geosciences & Biosciences. The STEM was supported under the Laboratory Directed Research and Development Program: Chemical Imaging Initiative at Pacific Northwest National Laboratory (PNNL), a multi-program national laboratory operated for DOE by Battelle under Contract DE-AC05-76RL01830. STEM was performed at EMSL, a DOE Office of Science user facility sponsored by the Office of Biological and Environmental Research and located at PNNL.« less

Challenges and opportunities for early-career Teaching-Focussed academics in the biosciences.

PubMed

Hubbard, Katharine; Gretton, Sarah; Jones, Katherine; Tallents, Lucy

2015-01-01

Twenty-seven percent of academics in UK Higher Education (HE) are in Teaching-Focussed positions, making major contributions to undergraduate programmes in an era of high student expectations when it comes to teaching quality. However, institutional support for Teaching-Focussed academics is often limited, both in terms of peer networking and opportunities for career development. As four early-career stage Teaching-Focussed academics working in a variety of institutions, we explore what motivated our choices to make teaching our primary academic activity, and the challenges that we have faced in doing so. In addition to highlighting the need for universities to fully recognise the achievements of teaching staff, we discuss the role that the various biosciences learned societies have in supporting Teaching-Focussed academics. We identify that there is a need for the learned societies to come together and pool their expertise in this area. The fragmented nature of the Teaching-Focussed academic community means that clear sources of national support are needed in order to best enable the next generation of bioscience educators to reach their full potential.

Challenges and opportunities for early-career Teaching-Focussed academics in the biosciences

PubMed Central

Hubbard, Katharine; Gretton, Sarah; Jones, Katherine; Tallents, Lucy

2015-01-01

Twenty-seven percent of academics in UK Higher Education (HE) are in Teaching-Focussed positions, making major contributions to undergraduate programmes in an era of high student expectations when it comes to teaching quality. However, institutional support for Teaching-Focussed academics is often limited, both in terms of peer networking and opportunities for career development. As four early-career stage Teaching-Focussed academics working in a variety of institutions, we explore what motivated our choices to make teaching our primary academic activity, and the challenges that we have faced in doing so. In addition to highlighting the need for universities to fully recognise the achievements of teaching staff, we discuss the role that the various biosciences learned societies have in supporting Teaching-Focussed academics. We identify that there is a need for the learned societies to come together and pool their expertise in this area. The fragmented nature of the Teaching-Focussed academic community means that clear sources of national support are needed in order to best enable the next generation of bioscience educators to reach their full potential. PMID:25977754

LDRD FY2004 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kotta, P. R.; Kline, K. M.

2005-02-28

The Laboratory Directed Research and Development (LDRD) Program is our primary means for pursuing innovative, long-term, high-risk, and potentially high-payoff research that supports the missions of the Laboratory, the Department of Energy, and the National Nuclear Security Administration in national security, homeland security, energy security, environmental management, bioscience and healthcare technology, and breakthroughs in fundamental science and technology. The LDRD Program was authorized by Congress in 1991 and is administered by the Laboratory Science and Technology Office. The accomplishments described in this Annual Report demonstrate how the LDRD portfolio is strongly aligned with these missions and contributes to the Laboratory’smore » success in meeting its goals. The LDRD budget of $69.8 million for FY2004 sponsored 220 projects. These projects were selected through an extensive peer-review process to ensure the highest scientific and technical quality and mission relevance. Each year, the number of meritorious proposals far exceeds the funding available, making the selection a challenging one indeed. Our ongoing investments in LDRD have reaped long-term rewards for the Laboratory and the Nation. Many Laboratory programs trace their roots to research thrusts that began several years ago under LDRD sponsorship. In addition, many LDRD projects contribute to more than one mission area, leveraging the Laboratory’s multidisciplinary team approach to science and technology. Safeguarding the Nation from terrorist activity and the proliferation of weapons of mass destruction will be an enduring mission of this Laboratory, for which LDRD will continue to play a vital role. The LDRD Program is a success story. Our projects continue to win national recognition for excellence through prestigious awards, papers published in peer-reviewed journals, and patents granted. With its reputation for sponsoring innovative projects, the LDRD Program is also a major vehicle for attracting and retaining the best and the brightest technical staff and for establishing collaborations with universities, industry, and other scientific and research institutions. By keeping the Laboratory at the forefront of science and technology, the LDRD Program enables us to meet our mission challenges, especially those of our ever-evolving national security and homeland security missions.« less

PREFACE: 2nd International Conference on Competitive Materials and Technological Processes (IC-CMTP2)

NASA Astrophysics Data System (ADS)

László, Gömze A.

2013-12-01

Competitiveness is one of the most important factors in our life and it plays a key role in the efficiency both of organizations and societies. The more scientifically supported and prepared organizations develop more competitive materials with better physical, chemical and biological properties and the leading companies apply more competitive equipment and technology processes. The aims of the 2nd International Conference on Competitive Materials and Technology Processes (ic-cmtp2) are the following: Promote new methods and results of scientific research in the fields of material, biological, environmental and technology sciences; Change information between the theoretical and applied sciences as well as technical and technological implantations. Promote the communication between the scientist of different nations, countries and continents. Among the major fields of interest are materials with extreme physical, chemical, biological, medical, thermal, mechanical properties and dynamic strength; including their crystalline and nano-structures, phase transformations as well as methods of their technological processes, tests and measurements. Multidisciplinary applications of materials science and technological problems encountered in sectors like ceramics, glasses, thin films, aerospace, automotive and marine industry, electronics, energy, construction materials, medicine, biosciences and environmental sciences are of particular interest. In accordance to the program of the conference ic-cmtp2, more than 250 inquiries and registrations from different organizations were received. Researchers from 36 countries in Asia, Europe, Africa, North and South America arrived at the venue of conference. Including co-authors, the research work of more than 500 scientists are presented in this volume. Professor Dr Gömze A László Chair, ic-cmtp2 The PDF also contains lists of the boards, session chairs and sponsors.

Advanced Plant Habitat Flight Unit #1

NASA Image and Video Library

2017-07-24

Inside a laboratory in the Space Station Processing Facility at NASA's Kennedy Space Center in Florida, a quality technician checks the hardware for the Advanced Plant Habitat flight unit. The flight unit is an exact replica of the APH that was delivered to the International Space Station. Validation tests and post-delivery checkout was performed to prepare for space station in-orbit APH activities. The flight unit will be moved to the International Space Station Environmental Simulator to begin an experiment verification test for the science that will fly on the first mission, PH-01. Developed by NASA and ORBITEC of Madison, Wisconsin, the APH is the largest plant chamber built for the agency. It is a fully automated plant growth facility that will be used to conduct bioscience research on the space station.

Advanced Plant Habitat Flight Unit #1

NASA Image and Video Library

2017-07-24

Inside a laboratory in the Space Station Processing Facility at NASA's Kennedy Space Center in Florida, quality technicians check the hardware for the Advanced Plant Habitat flight unit. The flight unit is an exact replica of the APH that was delivered to the International Space Station. Validation tests and post-delivery checkout was performed to prepare for space station in-orbit APH activities. The flight unit will be moved to the International Space Station Environmental Simulator to begin an experiment verification test for the science that will fly on the first mission, PH-01. Developed by NASA and ORBITEC of Madison, Wisconsin, the APH is the largest plant chamber built for the agency. It is a fully automated plant growth facility that will be used to conduct bioscience research on the space station.

Advanced Plant Habitat Flight Unit #1

NASA Image and Video Library

2017-07-24

Inside a laboratory in the Space Station Processing Facility at NASA's Kennedy Space Center in Florida, quality technicians check components of the hardware for the Advanced Plant Habitat flight unit. The flight unit is an exact replica of the APH that was delivered to the International Space Station. Validation tests and post-delivery checkout was performed to prepare for space station in-orbit APH activities. The flight unit will be moved to the International Space Station Environmental Simulator to begin an experiment verification test for the science that will fly on the first mission, PH-01. Developed by NASA and ORBITEC of Madison, Wisconsin, the APH is the largest plant chamber built for the agency. It is a fully automated plant growth facility that will be used to conduct bioscience research on the space station.

Advanced Plant Habitat Flight Unit #1

NASA Image and Video Library

2017-07-24

Inside a laboratory in the Space Station Processing Facility at NASA's Kennedy Space Center in Florida, a quality technician checks the control panel on hardware for the Advanced Plant Habitat flight unit. The flight unit is an exact replica of the APH that was delivered to the International Space Station. Validation tests and post-delivery checkout was performed to prepare for space station in-orbit APH activities. The flight unit will be moved to the International Space Station Environmental Simulator to begin an experiment verification test for the science that will fly on the first mission, PH-01. Developed by NASA and ORBITEC of Madison, Wisconsin, the APH is the largest plant chamber built for the agency. It is a fully automated plant growth facility that will be used to conduct bioscience research on the space station.

How to Access and Sample the Deep Subsurface of Mars

NASA Technical Reports Server (NTRS)

Briggs, G.; Blacic, J.; Dreesen, D.; Mockler, T.

2000-01-01

We are developing a technology roadmap to support a series of Mars lander missions aimed at successively deeper and more comprehensive explorations of the Martian subsurface. The proposed mission sequence is outlined. Key to this approach is development of a drilling and sampling technology robust and flexible enough to successfully penetrate the presently unknown subsurface geology and structure. Martian environmental conditions, mission constraints of power and mass and a requirement for a high degree of automation all limit applicability of many proven terrestrial drilling technologies. Planetary protection and bioscience objectives further complicate selection of candidate systems. Nevertheless, recent advances in drilling technologies for the oil & gas, mining, underground utility and other specialty drilling industries convinces us that it will be possible to meet science and operational objectives of Mars subsurface exploration.

Developing library bioinformatics services in context: the Purdue University Libraries bioinformationist program.

PubMed

Rein, Diane C

2006-07-01

Purdue University is a major agricultural, engineering, biomedical, and applied life science research institution with an increasing focus on bioinformatics research that spans multiple disciplines and campus academic units. The Purdue University Libraries (PUL) hired a molecular biosciences specialist to discover, engage, and support bioinformatics needs across the campus. After an extended period of information needs assessment and environmental scanning, the specialist developed a week of focused bioinformatics instruction (Bioinformatics Week) to launch system-wide, library-based bioinformatics services. The specialist employed a two-tiered approach to assess user information requirements and expectations. The first phase involved careful observation and collection of information needs in-context throughout the campus, attending laboratory meetings, interviewing department chairs and individual researchers, and engaging in strategic planning efforts. Based on the information gathered during the integration phase, several survey instruments were developed to facilitate more critical user assessment and the recovery of quantifiable data prior to planning. Given information gathered while working with clients and through formal needs assessments, as well as the success of instructional approaches used in Bioinformatics Week, the specialist is developing bioinformatics support services for the Purdue community. The specialist is also engaged in training PUL faculty librarians in bioinformatics to provide a sustaining culture of library-based bioinformatics support and understanding of Purdue's bioinformatics-related decision and policy making.

Development and evaluation of a peer-tutoring program for graduate students*.

PubMed

Copeland, H Liesel; Kinzy, Terri Goss

2005-03-01

Many interdisciplinary Ph.D. programs admit students of different educational backgrounds who receive a first year of a general curriculum education. However, student preparation for this curriculum varies, and methods are needed to provide academic support. Graduate student peer tutoring was piloted as an initiative funded by a National Institutes of Health (NIH) Initiative for Minority Student Development award to the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School (UMDNJ-RWJMS) and is now offered to all students in the interdisciplinary Molecular Biosciences Ph.D. program between Rutgers, The State University of New Jersey, and UMDNJ-RWJMS. Tutoring occurs individually or in small groups and has grown over the past 5 years in the number of students tutored and hours of tutoring. The program was evaluated by surveying and interviewing both tutors and students concerning process variables (e.g. awareness, frequency) and impact variables (e.g. perceived benefits, motivators), as well as by assessing changes in exam scores for the four core courses of the first-year graduate curriculum. Copyright © 2005 International Union of Biochemistry and Molecular Biology, Inc.

TA-03-0035 Press Building – D&D

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hasenack, Marvin Leroy

The Press Building was constructed in 1954 with 15,073 ft 2 of floor space. It was built to house a 5000 ton double action Lake Erie hydraulic press and a uranium casting area. Missions included uranium activities associated with the Nuclear Weapons and Rover Rocket programs. At the end of the Rover program, the building continued to support various uranium materials science projects until the building was placed into a cold and dark status in 2013 and then was demolished in 2017. The building interior, the press, and associated systems were radiological contaminated and disposed of as low level waste.more » The demolition of this building opened up valuable real estate in the TA-3 area for the future construction of an ~11,000 Sq. Ft. Biosafety Level 2 laboratory and office building. This building will support the ongoing Bioscience Division mission at the laboratory.« less

KSC-07pd3534

NASA Image and Video Library

2007-12-03

KENNEDY SPACE CENTER, FLA. -- STS-122 Mission Specialist Stanley Love checks the fit of his helmet for his launch and entry suit before space shuttle Atlantis' launch scheduled for 4:31 p.m. EST on Dec. 6. Love will make his first shuttle flight. Atlantis will carry the Columbus Lab, Europe’s largest contribution to the construction of the International Space Station. It will support scientific and technological research in a microgravity environment. Columbus, a program of ESA, is a multifunctional, pressurized laboratory that will be permanently attached to Node 2 of the space station to carry out experiments in materials science, fluid physics and biosciences, as well as to perform a number of technological applications. Photo credit: NASA/Kim Shiflett

KSC-07pd3531

NASA Image and Video Library

2007-12-03

KENNEDY SPACE CENTER, FLA. -- STS-122 Mission Specialist Stanley Love dons his launch and entry suit for a final fitting before space shuttle Atlantis' launch scheduled for 4:31 p.m. EST on Dec. 6. Love will make his first shuttle flight. Atlantis will carry the Columbus Lab, Europe’s largest contribution to the construction of the International Space Station. It will support scientific and technological research in a microgravity environment. Columbus, a program of ESA, is a multifunctional, pressurized laboratory that will be permanently attached to Node 2 of the space station to carry out experiments in materials science, fluid physics and biosciences, as well as to perform a number of technological applications. Photo credit: NASA/Kim Shiflett

Conference scene: molecular pharming: manufacturing medicines in plants.

PubMed

Lössl, Andreas G; Clarke, Jihong L

2013-01-01

Within the expanding area of molecular pharming, the development of plants for manufacturing immunoglobulins, enzymes, virus-like particles and vaccines has become a major focus point. On 21 September 2012, the meeting 'Molecular Pharming - recent progress in manufacturing medicines in plants', hosted by EuroSciCon, was held at the Bioscience Catalyst campus, Stevenage, UK. The scientific program of this eventful meeting covered diverse highlights of biopharming: monoclonal antibodies, virus-like particles from transient and chloroplast expression systems, for example, for Dengue and HPV, apolipoproteins from safflower seeds, and new production platforms, such as potato or hydroponics by rhizosecretion. This report summarizes the stimulating scientific presentations and fruitful panel discussions on the current topics in this promising research field.

Communications Specialist | Center for Cancer Research

Cancer.gov

Be part of our mission to support research against cancer. We have an exciting opportunity for a talented communicator to join our team and be part of the effort to find cures for cancer. We are looking for a creative, team-oriented communications professional, with strong writing skills to publicize our research advances, employment and training opportunities and clinical trials program. Work involves production of a monthly internal newsletter with circulation of 3,000, writing and editing a variety of stories, such as features on patients, and developing content for communications tactics. Must have a Bachelor’s degree in Communications, Biosciences and/or related field; Master’s degree or equivalent professional experience preferred. Full time position, business hours.

KSC-07pd3536

NASA Image and Video Library

2007-12-03

KENNEDY SPACE CENTER, FLA. -- STS-122 Mission Specialist Rex Walheim checks the helmet to his launch and entry suit for a final fitting before space shuttle Atlantis' launch scheduled for 4:31 p.m. EST on Dec. 6. Walheim will make his second shuttle flight. Atlantis will carry the Columbus Lab, Europe’s largest contribution to the construction of the International Space Station. It will support scientific and technological research in a microgravity environment. Columbus, a program of ESA, is a multifunctional, pressurized laboratory that will be permanently attached to Node 2 of the space station to carry out experiments in materials science, fluid physics and biosciences, as well as to perform a number of technological applications. Photo credit: NASA/Kim Shiflett

KSC-07pd3533

NASA Image and Video Library

2007-12-03

KENNEDY SPACE CENTER, FLA. -- STS-122 Mission Specialist Rex Walheim checks the helmet to his launch and entry suit for a final fitting before space shuttle Atlantis' launch scheduled for 4:31 p.m. EST on Dec. 6. Walheim will make his second shuttle flight. Atlantis will carry the Columbus Lab, Europe’s largest contribution to the construction of the International Space Station. It will support scientific and technological research in a microgravity environment. Columbus, a program of ESA, is a multifunctional, pressurized laboratory that will be permanently attached to Node 2 of the space station to carry out experiments in materials science, fluid physics and biosciences, as well as to perform a number of technological applications. Photo credit: NASA/Kim Shiflett

KSC-07pd3535

NASA Image and Video Library

2007-12-03

KENNEDY SPACE CENTER, FLA. -- STS-122 Mission Specialist Leland Melvin dons his launch and entry suit for a final fitting before space shuttle Atlantis' launch scheduled for 4:31 p.m. EST on Dec. 6. Melvin will make his first shuttle flight. Atlantis will carry the Columbus Lab, Europe’s largest contribution to the construction of the International Space Station. It will support scientific and technological research in a microgravity environment. Columbus, a program of ESA, is a multifunctional, pressurized laboratory that will be permanently attached to Node 2 of the space station to carry out experiments in materials science, fluid physics and biosciences, as well as to perform a number of technological applications. Photo credit: NASA/Kim Shiflett

KSC-07pd3537

NASA Image and Video Library

2007-12-03

KENNEDY SPACE CENTER, FLA. -- STS-122 Mission Specialist Leland Melvin tests his gloves for a final fitting before space shuttle Atlantis' launch scheduled for 4:31 p.m. EST on Dec. 6. Melvin will make his first shuttle flight. Atlantis will carry the Columbus Lab, Europe’s largest contribution to the construction of the International Space Station. It will support scientific and technological research in a microgravity environment. Columbus, a program of ESA, is a multifunctional, pressurized laboratory that will be permanently attached to Node 2 of the space station to carry out experiments in materials science, fluid physics and biosciences, as well as to perform a number of technological applications. Photo credit: NASA/Kim Shiflett

Design of an integrated team project as bachelor thesis in bioscience engineering

NASA Astrophysics Data System (ADS)

Peeters, Marie-Christine; Londers, Elsje; Van der Hoeven, Wouter

2014-11-01

Following the decision at the KU Leuven to implement the educational concept of guided independent learning and to encourage students to participate in scientific research, the Faculty of Bioscience Engineering decided to introduce a bachelor thesis. Competencies, such as communication, scientific research and teamwork, need to be present in the design of this thesis. Because of the high number of students and the multidisciplinary nature of the graduates, all research divisions of the faculty are asked to participate. The yearly surveys and hearings were used for further optimisation. The actual design of this bachelor thesis is presented and discussed in this paper.

LDRD Annual Report FY2006

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sketchley, J A; Kotta, P; De Yoreo, J

The Laboratory Directed Research and Development (LDRD) Program, authorized by Congress in 1991 and administered by the Laboratory Science and Technology Office, is our primary means for pursuing innovative, long-term, high-risk, and potentially high-payoff research that supports the missions of the Laboratory, the Department of Energy, and National Nuclear Security Administration in national security, energy security, environmental management, bioscience and technology to improve human health, and breakthroughs in fundamental science and technology. The accomplishments described in this Annual Report demonstrate the strong alignment of the LDRD portfolio with these missions and contribute to the Laboratory's success in meeting its goals.more » The LDRD budget of $92 million for FY2006 sponsored 188 projects. These projects were selected through an extensive peer-review process to ensure the highest scientific quality and mission relevance. Each year, the number of deserving proposals far exceeds the funding available, making the selection a tough one indeed. Our ongoing investments in LDRD have reaped long-term rewards for the Laboratory and the nation. Many Laboratory programs trace their roots to research thrusts that began several years ago under LDRD sponsorship. In addition, many LDRD projects contribute to more than one mission area, leveraging the Laboratory's multidisciplinary team approach to science and technology. Safeguarding the nation from terrorist activity and the proliferation of weapons of mass destruction will be an enduring mission of this Laboratory, for which LDRD will continue to play a vital role. The LDRD Program is a success story. Our projects continue to win national recognition for excellence through prestigious awards, papers published in peer-reviewed journals, and patents granted. With its reputation for sponsoring innovative projects, the LDRD Program is also a major vehicle for attracting and retaining the best and the brightest technical staff and for establishing collaborations with universities, industry, and other scientific and research institutions. By keeping the Laboratory at the forefront of science and technology, the LDRD Program enables us to meet our mission challenges, especially those of our ever-evolving national security mission.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mann, Reinhold C.

This is the first formal progress report issued by the ORNL Life Sciences Division. It covers the period from February 1997 through December 1998, which has been critical in the formation of our new division. The legacy of 50 years of excellence in biological research at ORNL has been an important driver for everyone in the division to do their part so that this new research division can realize the potential it has to make seminal contributions to the life sciences for years to come. This reporting period is characterized by intense assessment and planning efforts. They included thorough scrutinymore » of our strengths and weaknesses, analyses of our situation with respect to comparative research organizations, and identification of major thrust areas leading to core research efforts that take advantage of our special facilities and expertise. Our goal is to develop significant research and development (R&D) programs in selected important areas to which we can make significant contributions by combining our distinctive expertise and resources in the biological sciences with those in the physical, engineering, and computational sciences. Significant facilities in mouse genomics, mass spectrometry, neutron science, bioanalytical technologies, and high performance computing are critical to the success of our programs. Research and development efforts in the division are organized in six sections. These cluster into two broad areas of R&D: systems biology and technology applications. The systems biology part of the division encompasses our core biological research programs. It includes the Mammalian Genetics and Development Section, the Biochemistry and Biophysics Section, and the Computational Biosciences Section. The technology applications part of the division encompasses the Assessment Technology Section, the Environmental Technology Section, and the Toxicology and Risk Analysis Section. These sections are the stewards of the division's core competencies. The common mission of the division is to advance science and technology to understand complex biological systems and their relationship with human health and the environment.« less

Unique Sensor Plane Maps Invisible Toxins for First Responders

ScienceCinema

Kroutil, Robert; Thomas, Mark; Aten, Keith

2017-12-09

A unique airborne emergency response tool, ASPECT is a Los Alamos/U.S. Environmental Protection Agency project that can put chemical and radiological mapping tools in the air over an accident scene. The name ASPECT is an acronym for Airborne Spectral Photometric Environmental Collection Technology. Update, Sept. 19, 2008: Flying over storm-damaged refineries and chemical factories, a twin-engine plane carrying the ASPECT (Airborne Spectral Photometric Environmental Collection Technology) system has been on duty throughout the recent hurricanes that have swept the Florida and Gulf Coast areas. ASPECT is a project of the U.S. U.S. Environmental Protection Agencys National Decontamination Team. Los Alamos National Laboratory leads a science and technology program supporting the EPA and the ASPECT aircraft. Casting about with a combination of airborne photography and infrared spectroscopy, the highly instrumented plane provides emergency responders on the ground with a clear concept of where danger lies, and the nature of the sometimes-invisible plumes that could otherwise kill them. ASPECT is the nations only 24/7 emergency response aircraft with chemical plume mapping capability. Bob Kroutil of Bioscience Division is the project leader, and while he said the team has put in long hours, both on the ground and in the air, its a worthwhile effort. The plane flew over 320 targeted sites in four days, he noted. Prior to the deployment to the Gulf Coast, the plane had been monitoring the Democratic National Convention in Denver, Colorado. Los Alamos National Laboratory Divisions that are supporting ASPECT include, in addition to B-Division, CTN-5: Networking Engineering and IRM-CAS: Communication, Arts, and Services. Leslie Mansell, CTN-5, and Marilyn Pruitt, IRM-CAS, were recognized the the U.S. EPA for their outstanding support to the hurricane response of Gustav in Louisiana and Ike in Texas. The information from the data collected in the most recent event, Hurricane Ike, was sent to the EPA Region 6 Rapid Needs Assessment and the State of Texas Joint Field Office in Austin, Texas. It appears that though there is considerable damage in Galveston and Texas City, there are fewer chemical leaks than during either hurricanes Katrina or Rita. Specific information gathered from the data was reported out to the U.S. Environmental Protection Agency Headquarters, the Federal Emergency Management Agency, the Department of Homeland Security, and the State of Texas Emergency Management Agency.

Near quantitative agreement of model free DFT- MD predictions with XAFS observations of the hydration structure of highly charged transition metal ions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fulton, John L.; Bylaska, Eric J.; Bogatko, Stuart A.

DFT-MD simulations (PBE96 and PBE0) with MD-XAFS scattering calculations (FEFF9) show near quantitative agreement with new and existing XAFS measurements for a comprehensive series of transition metal ions which interact with their hydration shells via complex mechanisms (high spin, covalency, charge transfer, etc.). This work was supported by the U.S. Department of Energy (DOE), Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences and Biosciences. Pacific Northwest National Laboratory (PNNL) is operated for the U.S. DOE by Battelle. A portion of the research was performed using EMSL, a national scientific user facility sponsored by the U.S. DOE's Office ofmore » Biological and Environmental Research and located at Pacific Northwest National Laboratory.« less

Advanced Plant Habitat Flight Unit #1

NASA Image and Video Library

2017-07-24

Inside a laboratory in the Space Station Processing Facility at NASA's Kennedy Space Center in Florida, LED plant growth lights are being checked out on the hardware for the Advanced Plant Habitat flight unit. The flight unit is an exact replica of the APH that was delivered to the International Space Station. Validation tests and post-delivery checkout was performed to prepare for space station in-orbit APH activities. The flight unit will be moved to the International Space Station Environmental Simulator to begin an experiment verification test for the science that will fly on the first mission, PH-01. Developed by NASA and ORBITEC of Madison, Wisconsin, the APH is the largest plant chamber built for the agency. It is a fully automated plant growth facility that will be used to conduct bioscience research on the space station.

Biosynthesis of luminescent CdS quantum dots using plant hairy root culture

NASA Astrophysics Data System (ADS)

Borovaya, Mariya N.; Naumenko, Antonina P.; Matvieieva, Nadia A.; Blume, Yaroslav B.; Yemets, Alla I.

2014-12-01

CdS nanoparticles have a great potential for application in chemical research, bioscience and medicine. The aim of this study was to develop an efficient and environmentally-friendly method of plant-based biosynthesis of CdS quantum dots using hairy root culture of Linaria maroccana L. By incubating Linaria root extract with inorganic cadmium sulfate and sodium sulfide we synthesized stable luminescent CdS nanocrystals with absorption peaks for UV-visible spectrometry at 362 nm, 398 nm and 464 nm, and luminescent peaks at 425, 462, 500 nm. Transmission electron microscopy of produced quantum dots revealed their spherical shape with a size predominantly from 5 to 7 nm. Electron diffraction pattern confirmed the wurtzite crystalline structure of synthesized cadmium sulfide quantum dots. These results describe the first successful attempt of quantum dots synthesis using plant extract.

Dispatches from the Interface of Salivary Bioscience and Neonatal Research

PubMed Central

Voegtline, Kristin M.; Granger, Douglas A.

2014-01-01

The emergence of the interdisciplinary field of salivary bioscience has created opportunity for neonatal researchers to measure multiple components of biological systems non-invasively in oral fluids. The implications are profound and potentially high impact. From a single oral fluid specimen, information can be obtained about a vast array of biological systems (e.g., endocrine, immune, autonomic nervous system) and the genetic polymorphisms related to individual differences in their function. The purpose of this review is to describe the state of the art for investigators interested in integrating these unique measurement tools into the current and next generation of research on gonadal steroid exposure during the prenatal and neonatal developmental periods. PMID:24624119

Harnessing the power of communities: career networking strategies for bioscience PhD students and postdoctoral researchers.

PubMed

Blackford, Sarah

2018-04-01

With an ever more competitive global labour market, coupled with an ever-increasing population of PhD-qualified graduates, the ability to communicate effectively and build strategic connections with others can be advantageous in the job-search process. Whether in pursuit of a tenure-track or non-academic position, many postdoctoral researchers and PhD students will benefit from networking as early as possible to enhance their career prospects. Sometimes viewed cynically as 'using people' or dismissed as 'the old boy network,' the ability to make meaningful connections and build relationships can be more valuable than other job-related skills in order to gain entry to, and progress within, many professions. This mini-review highlights the positive influence of networking and how bioscience PhD students and postdoctoral researchers can harness the power of communities to achieve career success. It is argued that those who make connections and promote personal patronage through networking can gain an advantage over their contemporaries. A summary of key theories and research studies that underpin the practice of networking provides credence to these assertions, which are further substantiated with examples pertinent to the academic community. Although primarily focussed on the biosciences, much of the content is applicable to other scientists at a similar career stage.

KSC-07pd3532

NASA Image and Video Library

2007-12-03

KENNEDY SPACE CENTER, FLA. -- STS-122 Mission Specialist Hans Schlegel checks the helmet to his launch and entry suit for a final fitting before space shuttle Atlantis' launch scheduled for 4:31 p.m. EST on Dec. 6. Schlegel, who represents the European Space Agency, will make his second shuttle flight. Atlantis will carry the Columbus Lab, Europe’s largest contribution to the construction of the International Space Station. It will support scientific and technological research in a microgravity environment. Columbus, a program of ESA, is a multifunctional, pressurized laboratory that will be permanently attached to Node 2 of the space station to carry out experiments in materials science, fluid physics and biosciences, as well as to perform a number of technological applications. Photo credit: NASA/Kim Shiflett

KSC-07pd3530

NASA Image and Video Library

2007-12-03

KENNEDY SPACE CENTER, FLA. -- STS-122 Mission Specialist Hans Schlegel dons his launch and entry suit for a final fitting before space shuttle Atlantis' launch scheduled for 4:31 p.m. EST on Dec. 6. Schlegel, who represents the European Space Agency, will make his second shuttle flight. Atlantis will carry the Columbus Lab, Europe’s largest contribution to the construction of the International Space Station. It will support scientific and technological research in a microgravity environment. Columbus, a program of ESA, is a multifunctional, pressurized laboratory that will be permanently attached to Node 2 of the space station to carry out experiments in materials science, fluid physics and biosciences, as well as to perform a number of technological applications. Photo credit: NASA/Kim Shiflett

Life sciences payload definition and integration study. Volume 4: Appendix, costs, and data management requirements of the dedicated 30-day laboratory. [carry-on laboratory for Spacelab

NASA Technical Reports Server (NTRS)

1974-01-01

The results of the updated 30-day life sciences dedicated laboratory scheduling and costing activities are documented, and the 'low cost' methodology used to establish individual equipment item costs is explained in terms of its allowances for equipment that is commerical off-the-shelf, modified commercial, and laboratory prototype; a method which significantly lowers program costs. The costs generated include estimates for non-recurring development, recurring production, and recurring operations costs. A cost for a biomedical emphasis laboratory and a Delta cost to provide a bioscience and technology laboratory were also generated. All cost reported are commensurate with the design and schedule definitions available.

KSC-07pd2838

NASA Image and Video Library

2007-10-11

KENNEDY SPACE CENTER, FLA. -- In the Vehicle Assembly Building at NASA's Kennedy Space Center, the frustum is lifted from a transporter to be moved onto a stand. The solid rocket booster segment will be added to the stack for space shuttle Atlantis, launch vehicle for mission STS-122 targeted for a December launch. Atlantis will be carrying the Columbus Laboratory, Europe’s largest contribution to the construction of the International Space Station. It will support scientific and technological research in a microgravity environment. Columbus, a program of ESA, is a multifunctional, pressurized laboratory that will be permanently attached to Node 2 of the space station to carry out experiments in materials science, fluid physics and biosciences, as well as to perform a number of technological applications. Photo credit: NASA/Jack Pfaller

KSC-07pd2837

NASA Image and Video Library

2007-10-11

KENNEDY SPACE CENTER, FLA. -- In the Vehicle Assembly Building at NASA's Kennedy Space Center, the frustum is lifted from a transporter to be moved onto a stand. The solid rocket booster segment will be added to the stack for space shuttle Atlantis, launch vehicle for mission STS-122 targeted for a December launch. Atlantis will be carrying the Columbus Laboratory, Europe’s largest contribution to the construction of the International Space Station. It will support scientific and technological research in a microgravity environment. Columbus, a program of ESA, is a multifunctional, pressurized laboratory that will be permanently attached to Node 2 of the space station to carry out experiments in materials science, fluid physics and biosciences, as well as to perform a number of technological applications. Photo credit: NASA/Jack Pfaller

77 FR 51786 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-27

... to increasing the number and quality of the nation's scientists and engineers. Application... Engineering, Biosciences, Chemical Engineering, Chemistry, Civil Engineering, Cognitive, Neural, and...

New developments in crystallography: exploring its technology, methods and scope in the molecular biosciences.

PubMed

Helliwell, John R

2017-08-31

Since the Protein Data Bank (PDB) was founded in 1971, there are now over 120,000 depositions, the majority of which are from X-ray crystallography and 90% of those made use of synchrotron beamlines. At the Cambridge Structure Database (CSD), founded in 1965, there are more than 800,000 'small molecule' crystal structure depositions and a very large number of those are relevant in the biosciences as ligands or cofactors. The technology for crystal structure analysis is still developing rapidly both at synchrotrons and in home labs. Determination of the details of the hydrogen atoms in biological macromolecules is well served using neutrons as probe. Large multi-macromolecular complexes cause major challenges to crystallization; electrons as probes offer unique advantages here. Methods developments naturally accompany technology change, mainly incremental but some, such as the tuneability, intensity and collimation of synchrotron radiation, have effected radical changes in capability of biological crystallography. In the past few years, the X-ray laser has taken X-ray crystallography measurement times into the femtosecond range. In terms of applications many new discoveries have been made in the molecular biosciences. The scope of crystallographic techniques is indeed very wide. As examples, new insights into chemical catalysis of enzymes and relating ligand bound structures to thermodynamics have been gained but predictive power is seen as not yet achieved. Metal complexes are also an emerging theme for biomedicine applications. Our studies of coloration of live and cooked lobsters proved to be an unexpected favourite with the public and schoolchildren. More generally, public understanding of the biosciences and crystallography's role within the field have been greatly enhanced by the United Nations International Year of Crystallography coordinated by the International Union of Crystallography. This topical review describes each of these areas along with illustrative results to document the scope of each methodology. © 2017 The Author(s).

Full Text and Figure Display Improves Bioscience Literature Search

PubMed Central

Divoli, Anna; Wooldridge, Michael A.; Hearst, Marti A.

2010-01-01

When reading bioscience journal articles, many researchers focus attention on the figures and their captions. This observation led to the development of the BioText literature search engine [1], a freely available Web-based application that allows biologists to search over the contents of Open Access Journals, and see figures from the articles displayed directly in the search results. This article presents a qualitative assessment of this system in the form of a usability study with 20 biologist participants using and commenting on the system. 19 out of 20 participants expressed a desire to use a bioscience literature search engine that displays articles' figures alongside the full text search results. 15 out of 20 participants said they would use a caption search and figure display interface either frequently or sometimes, while 4 said rarely and 1 said undecided. 10 out of 20 participants said they would use a tool for searching the text of tables and their captions either frequently or sometimes, while 7 said they would use it rarely if at all, 2 said they would never use it, and 1 was undecided. This study found evidence, supporting results of an earlier study, that bioscience literature search systems such as PubMed should show figures from articles alongside search results. It also found evidence that full text and captions should be searched along with the article title, metadata, and abstract. Finally, for a subset of users and information needs, allowing for explicit search within captions for figures and tables is a useful function, but it is not entirely clear how to cleanly integrate this within a more general literature search interface. Such a facility supports Open Access publishing efforts, as it requires access to full text of documents and the lifting of restrictions in order to show figures in the search interface. PMID:20418942

The Benefits of Multi-Year Research Experiences: Differences in Novice and Experienced Students’ Reported Gains from Undergraduate Research

PubMed Central

Thiry, Heather; Weston, Timothy J.; Laursen, Sandra L.; Hunter, Anne-Barrie

2012-01-01

This mixed-methods study explores differences in novice and experienced undergraduate students’ perceptions of their cognitive, personal, and professional gains from engaging in scientific research. The study was conducted in four different undergraduate research (UR) programs at two research-extensive universities; three of these programs had a focus on the biosciences. Seventy-three entry-level and experienced student researchers participated in in-depth, semi-structured interviews and completed the quantitative Undergraduate Research Student Self-Assessment (URSSA) instrument. Interviews and surveys assessed students’ developmental outcomes from engaging in UR. Experienced students reported distinct personal, professional, and cognitive outcomes relative to their novice peers, including a more sophisticated understanding of the process of scientific research. Students also described the trajectories by which they developed not only the intellectual skills necessary to advance in science, but also the behaviors and temperament necessary to be a scientist. The findings suggest that students benefit from multi-year UR experiences. Implications for UR program design, advising practices, and funding structures are discussed. PMID:22949423

Immune cell changes in response to a swimming training session during a 24-h recovery period.

PubMed

Morgado, José P; Monteiro, Cristina P; Teles, Júlia; Reis, Joana F; Matias, Catarina; Seixas, Maria T; Alvim, Marta G; Bourbon, Mafalda; Laires, Maria J; Alves, Francisco

2016-05-01

Understanding the impact of training sessions on the immune response is crucial for the adequate periodization of training, to prevent both a negative influence on health and a performance impairment of the athlete. This study evaluated acute systemic immune cell changes in response to an actual swimming session, during a 24-h recovery period, controlling for sex, menstrual cycle phases, maturity, and age group. Competitive swimmers (30 females, 15 ± 1.3 years old; and 35 males, 16.5 ± 2.1 years old) performed a high-intensity training session. Blood samples were collected before, immediately after, 2 h after, and 24 h after exercise. Standard procedures for the assessment of leukogram by automated counting (Coulter LH 750, Beckman) and lymphocytes subsets by flow cytometry (FACS Calibur BD, Biosciences) were used. Subjects were grouped according to competitive age groups and pubertal Tanner stages. Menstrual cycle phase was monitored. The training session induced neutrophilia, lymphopenia, and a low eosinophil count, lasting for at least 2 h, independent of sex and maturity. At 24 h postexercise, the acquired immunity of juniors (15-17 years old), expressed by total lymphocytes and total T lymphocytes (CD3(+)), was not fully recovered. This should be accounted for when planning a weekly training program. The observed lymphopenia suggests a lower immune surveillance at the end of the session that may depress the immunity of athletes, highlighting the need for extra care when athletes are exposed to aggressive environmental agents such as swimming pools.

The impact of maths support tutorials on mathematics confidence and academic performance in a cohort of HE Animal Science students

PubMed Central

Amory, Jonathan

2014-01-01

Students embarking on a bioscience degree course, such as Animal Science, often do not have sufficient experience in mathematics. However, mathematics forms an essential and integral part of any bioscience degree and is essential to enhance employability. This paper presents the findings of a project looking at the effect of mathematics tutorials on a cohort of first year animal science and management students. The results of a questionnaire, focus group discussions and academic performance analysis indicate that small group tutorials enhance students’ confidence in maths and improve students’ academic performance. Furthermore, student feedback on the tutorial programme provides a deeper insight into student experiences and the value students assign to the tutorials. PMID:25024925

Contentious problems in bioscience and biotechnology: a pilot study of an approach to ethics education.

PubMed

Berry, Roberta M; Borenstein, Jason; Butera, Robert J

2013-06-01

This manuscript describes a pilot study in ethics education employing a problem-based learning approach to the study of novel, complex, ethically fraught, unavoidably public, and unavoidably divisive policy problems, called "fractious problems," in bioscience and biotechnology. Diverse graduate and professional students from four US institutions and disciplines spanning science, engineering, humanities, social science, law, and medicine analyzed fractious problems employing "navigational skills" tailored to the distinctive features of these problems. The students presented their results to policymakers, stakeholders, experts, and members of the public. This approach may provide a model for educating future bioscientists and bioengineers so that they can meaningfully contribute to the social understanding and resolution of challenging policy problems generated by their work.

The impact of maths support tutorials on mathematics confidence and academic performance in a cohort of HE Animal Science students.

PubMed

van Veggel, Nieky; Amory, Jonathan

2014-01-01

Students embarking on a bioscience degree course, such as Animal Science, often do not have sufficient experience in mathematics. However, mathematics forms an essential and integral part of any bioscience degree and is essential to enhance employability. This paper presents the findings of a project looking at the effect of mathematics tutorials on a cohort of first year animal science and management students. The results of a questionnaire, focus group discussions and academic performance analysis indicate that small group tutorials enhance students' confidence in maths and improve students' academic performance. Furthermore, student feedback on the tutorial programme provides a deeper insight into student experiences and the value students assign to the tutorials.

The Utility of Writing Assignments in Undergraduate Bioscience

PubMed Central

Libarkin, Julie; Ording, Gabriel

2012-01-01

We tested the hypothesis that engagement in a few, brief writing assignments in a nonmajors science course can improve student ability to convey critical thought about science. A sample of three papers written by students (n = 30) was coded for presence and accuracy of elements related to scientific writing. Scores for different aspects of scientific writing were significantly correlated, suggesting that students recognized relationships between components of scientific thought. We found that students' ability to write about science topics and state conclusions based on data improved over the course of three writing assignments, while the abilities to state a hypothesis and draw clear connections between human activities and environmental impacts did not improve. Three writing assignments generated significant change in student ability to write scientifically, although our results suggest that three is an insufficient number to generate complete development of scientific writing skills. PMID:22383616

Presidential Green Chemistry Challenge: 2001 Small Business Award

EPA Pesticide Factsheets

Presidential Green Chemistry Challenge 2001 award winner, EDEN Bioscience, discovered and commercialized harpins: nontoxic, naturally occurring, biodegradable proteins that activate a plant's defense and growth mechanisms.

Lawrence Livermore National Laboratory Environmental Report 2012

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, Henry E.; Armstrong, Dave; Blake, Rick G.

Lawrence Livermore National Laboratory (LLNL) is a premier research laboratory that is part of the National Nuclear Security Administration (NNSA) within the U.S. Department of Energy (DOE). As a national security laboratory, LLNL is responsible for ensuring that the nation’s nuclear weapons remain safe, secure, and reliable. The Laboratory also meets other pressing national security needs, including countering the proliferation of weapons of mass destruction and strengthening homeland security, and conducting major research in atmospheric, earth, and energy sciences; bioscience and biotechnology; and engineering, basic science, and advanced technology. The Laboratory is managed and operated by Lawrence Livermore National Security,more » LLC (LLNS), and serves as a scientific resource to the U.S. government and a partner to industry and academia. LLNL operations have the potential to release a variety of constituents into the environment via atmospheric, surface water, and groundwater pathways. Some of the constituents, such as particles from diesel engines, are common at many types of facilities while others, such as radionuclides, are unique to research facilities like LLNL. All releases are highly regulated and carefully monitored. LLNL strives to maintain a safe, secure and efficient operational environment for its employees and neighboring communities. Experts in environment, safety and health (ES&H) support all Laboratory activities. LLNL’s radiological control program ensures that radiological exposures and releases are reduced to as low as reasonably achievable to protect the health and safety of its employees, contractors, the public, and the environment. LLNL is committed to enhancing its environmental stewardship and managing the impacts its operations may have on the environment through a formal Environmental Management System. The Laboratory encourages the public to participate in matters related to the Laboratory’s environmental impact on the community by soliciting citizens’ input on matters of significant public interest and through various communications. The Laboratory also provides public access to information on its ES&H activities. LLNL consists of two sites—an urban site in Livermore, California, referred to as the “Livermore Site,” which occupies 1.3 square miles; and a rural Experimental Test Site, referred to as “Site 300,” near Tracy, California, which occupies 10.9 square miles. In 2012 the Laboratory had a staff of approximately 7000.« less

Lawrence Livermore National Laboratory Environmental Report 2013

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, H. E.; Bertoldo, N. A.; Blake, R. G.

Lawrence Livermore National Laboratory (LLNL) is a premier research laboratory that is part of the National Nuclear Security Administration (NNSA) within the U.S. Department of Energy (DOE). As a national security laboratory, LLNL is responsible for ensuring that the nation’s nuclear weapons remain safe, secure, and reliable. The Laboratory also meets other pressing national security needs, including countering the proliferation of weapons of mass destruction and strengthening homeland security, and conducting major research in atmospheric, earth, and energy sciences; bioscience and biotechnology; and engineering, basic science, and advanced technology. The Laboratory is managed and operated by Lawrence Livermore National Security,more » LLC (LLNS), and serves as a scientific resource to the U.S. government and a partner to industry and academia. LLNL operations have the potential to release a variety of constituents into the environment via atmospheric, surface water, and groundwater pathways. Some of the constituents, such as particles from diesel engines, are common at many types of facilities while others, such as radionuclides, are unique to research facilities like LLNL. All releases are highly regulated and carefully monitored. LLNL strives to maintain a safe, secure and efficient operational environment for its employees and neighboring communities. Experts in environment, safety and health (ES&H) support all Laboratory activities. LLNL’s radiological control program ensures that radiological exposures and releases are reduced to as low as reasonably achievable to protect the health and safety of its employees, contractors, the public, and the environment. LLNL is committed to enhancing its environmental stewardship and managing the impacts its operations may have on the environment through a formal Environmental Management System. The Laboratory encourages the public to participate in matters related to the Laboratory’s environmental impact on the community by soliciting citizens’ input on matters of significant public interest and through various communications. The Laboratory also provides public access to information on its ES&H activities. LLNL consists of two sites—an urban site in Livermore, California, referred to as the “Livermore Site,” which occupies 1.3 square miles; and a rural Experimental Test Site, referred to as “Site 300,” near Tracy, California, which occupies 10.9 square miles. In 2013 the Laboratory had a staff of approximately 6,300.« less

KSC-07pd2836

NASA Image and Video Library

2007-10-11

KENNEDY SPACE CENTER, FLA. -- In the Vehicle Assembly Building at NASA's Kennedy Space Center, the frustum is ready to be lifted from a transporter to move onto a stand. The solid rocket booster segment will be added to the stack for space shuttle Atlantis, launch vehicle for mission STS-122 targeted for a December launch. Atlantis will be carrying the Columbus Laboratory, Europe’s largest contribution to the construction of the International Space Station. It will support scientific and technological research in a microgravity environment. Columbus, a program of ESA, is a multifunctional, pressurized laboratory that will be permanently attached to Node 2 of the space station to carry out experiments in materials science, fluid physics and biosciences, as well as to perform a number of technological applications. Photo credit: NASA/Jack Pfaller

Plant Habitat Facility Clean

NASA Image and Video Library

2018-03-12

iss055e001931 (Mar. 12, 2018) --- Dwarf wheat plants during routine cleaning in the Advanced Plant Habitat Facility, a facility to conduct plant bioscience research on the International Space Stations (ISS).

The Application of Graphene and Its Derivatives to Energy Conversion, Storage, and Environmental and Biosensing Devices.

PubMed

Ali Tahir, Asif; Ullah, Habib; Sudhagar, Pitchaimuthu; Asri Mat Teridi, Mohd; Devadoss, Anitha; Sundaram, Senthilarasu

2016-06-01

Graphene (GR) and its derivatives are promising materials on the horizon of nanotechnology and material science and have attracted a tremendous amount of research interest in recent years. The unique atom-thick 2D structure with sp(2) hybridization and large specific surface area, high thermal conductivity, superior electron mobility, and chemical stability have made GR and its derivatives extremely attractive components for composite materials for solar energy conversion, energy storage, environmental purification, and biosensor applications. This review gives a brief introduction of GR's unique structure, band structure engineering, physical and chemical properties, and recent energy-related progress of GR-based materials in the fields of energy conversion (e.g., photocatalysis, photoelectrochemical water splitting, CO2 reduction, dye-sensitized and organic solar cells, and photosensitizers in photovoltaic devices) and energy storage (batteries, fuel cells, and supercapacitors). The vast coverage of advancements in environmental applications of GR-based materials for photocatalytic degradation of organic pollutants, gas sensing, and removal of heavy-metal ions is presented. Additionally, the use of graphene composites in the biosensing field is discussed. We conclude the review with remarks on the challenges, prospects, and further development of GR-based materials in the exciting fields of energy, environment, and bioscience. © 2016 The Chemical Society of Japan & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Communication and re-use of chemical information in bioscience

PubMed Central

Murray-Rust, Peter; Mitchell, John BO; Rzepa, Henry S

2005-01-01

The current methods of publishing chemical information in bioscience articles are analysed. Using 3 papers as use-cases, it is shown that conventional methods using human procedures, including cut-and-paste are time-consuming and introduce errors. The meaning of chemical terms and the identity of compounds is often ambiguous. valuable experimental data such as spectra and computational results are almost always omitted. We describe an Open XML architecture at proof-of-concept which addresses these concerns. Compounds are identified through explicit connection tables or links to persistent Open resources such as PubChem. It is argued that if publishers adopt these tools and protocols, then the quality and quantity of chemical information available to bioscientists will increase and the authors, publishers and readers will find the process cost-effective. PMID:16026614

Unique Sensor Plane Maps Invisible Toxins for First Responders

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kroutil, Robert; Thomas, Mark; Aten, Keith

A unique airborne emergency response tool, ASPECT is a Los Alamos/U.S. Environmental Protection Agency project that can put chemical and radiological mapping tools in the air over an accident scene. The name ASPECT is an acronym for Airborne Spectral Photometric Environmental Collection Technology. Update, Sept. 19, 2008: Flying over storm-damaged refineries and chemical factories, a twin-engine plane carrying the ASPECT (Airborne Spectral Photometric Environmental Collection Technology) system has been on duty throughout the recent hurricanes that have swept the Florida and Gulf Coast areas. ASPECT is a project of the U.S. U.S. Environmental Protection Agencys National Decontamination Team. Los Alamosmore » National Laboratory leads a science and technology program supporting the EPA and the ASPECT aircraft. Casting about with a combination of airborne photography and infrared spectroscopy, the highly instrumented plane provides emergency responders on the ground with a clear concept of where danger lies, and the nature of the sometimes-invisible plumes that could otherwise kill them. ASPECT is the nations only 24/7 emergency response aircraft with chemical plume mapping capability. Bob Kroutil of Bioscience Division is the project leader, and while he said the team has put in long hours, both on the ground and in the air, its a worthwhile effort. The plane flew over 320 targeted sites in four days, he noted. Prior to the deployment to the Gulf Coast, the plane had been monitoring the Democratic National Convention in Denver, Colorado. Los Alamos National Laboratory Divisions that are supporting ASPECT include, in addition to B-Division, CTN-5: Networking Engineering and IRM-CAS: Communication, Arts, and Services. Leslie Mansell, CTN-5, and Marilyn Pruitt, IRM-CAS, were recognized the the U.S. EPA for their outstanding support to the hurricane response of Gustav in Louisiana and Ike in Texas. The information from the data collected in the most recent event, Hurricane Ike, was sent to the EPA Region 6 Rapid Needs Assessment and the State of Texas Joint Field Office in Austin, Texas. It appears that though there is considerable damage in Galveston and Texas City, there are fewer chemical leaks than during either hurricanes Katrina or Rita. Specific information gathered from the data was reported out to the U.S. Environmental Protection Agency Headquarters, the Federal Emergency Management Agency, the Department of Homeland Security, and the State of Texas Emergency Management Agency.« less

Education: Bioscience Education through Bioparks.

ERIC Educational Resources Information Center

Robinson, Michael H.

1988-01-01

Suggests creating a biological park to stress the interrelationships between plants and animals. States that the techniques of a zoo should be applied to paleontology, anatomy, anthropology. Gives advantages of this creative concept. (RT)

Biosciences | Argonne National Laboratory

Science.gov Websites

understanding of the fundamental molecular mechanisms of life. Our goal is to enable important advances in processes at the molecular level. As a division, our goals include gaining predictive understanding of

Big Data: Are Biomedical and Health Informatics Training Programs Ready?

PubMed Central

Hersh, W.; Ganesh, A. U. Jai

2014-01-01

Summary Objectives The growing volume and diversity of health and biomedical data indicate that the era of Big Data has arrived for healthcare. This has many implications for informatics, not only in terms of implementing and evaluating information systems, but also for the work and training of informatics researchers and professionals. This article addresses the question: What do biomedical and health informaticians working in analytics and Big Data need to know? Methods We hypothesize a set of skills that we hope will be discussed among academic and other informaticians. Results The set of skills includes: Programming - especially with data-oriented tools, such as SQL and statistical programming languages; Statistics - working knowledge to apply tools and techniques; Domain knowledge - depending on one’s area of work, bioscience or health care; and Communication - being able to understand needs of people and organizations, and articulate results back to them. Conclusions Biomedical and health informatics educational programs must introduce concepts of analytics, Big Data, and the underlying skills to use and apply them into their curricula. The development of new coursework should focus on those who will become experts, with training aiming to provide skills in “deep analytical talent” as well as those who need knowledge to support such individuals. PMID:25123740

Big Data: Are Biomedical and Health Informatics Training Programs Ready? Contribution of the IMIA Working Group for Health and Medical Informatics Education.

PubMed

Otero, P; Hersh, W; Jai Ganesh, A U

2014-08-15

The growing volume and diversity of health and biomedical data indicate that the era of Big Data has arrived for healthcare. This has many implications for informatics, not only in terms of implementing and evaluating information systems, but also for the work and training of informatics researchers and professionals. This article addresses the question: What do biomedical and health informaticians working in analytics and Big Data need to know? We hypothesize a set of skills that we hope will be discussed among academic and other informaticians. The set of skills includes: Programming - especially with data-oriented tools, such as SQL and statistical programming languages; Statistics - working knowledge to apply tools and techniques; Domain knowledge - depending on one's area of work, bioscience or health care; and Communication - being able to understand needs of people and organizations, and articulate results back to them. Biomedical and health informatics educational programs must introduce concepts of analytics, Big Data, and the underlying skills to use and apply them into their curricula. The development of new coursework should focus on those who will become experts, with training aiming to provide skills in "deep analytical talent" as well as those who need knowledge to support such individuals.

Scientific Reports of Plasma Medicine and its Mechanism for Therapy in Plasma Bioscience Research Center

NASA Astrophysics Data System (ADS)

Choi, Eun Ha

2015-09-01

Scientific reports of plasma medicine and its basic mechanism for therapy will be introduced, especially, performed in Plasma Bioscience Research Center, Korea. We have investigated enhanced anticancer effect of monocytes and macrophages activated by nonthermal plasma which act as immune-modulator on these immune cells. Further, we investigated the action of the nanosecond pulsed plasma activated media (NPPAM) on the lung cancer cells and its DNA oxidation pathway. We observed OD induced apoptosis on melanocytes G361 cancer cells through DNA damage signaling cascade. We also studied DNA oxidation by extracting DNA from treated cancer cell and analyzed the effects of OD/OH/D2O2/H2O2 on protein modification and oxidation. Additionally, we attempted molecular docking approaches to check the action of D2O2 on the apoptosis related genes.

Teaching wave phenomena via biophysical applications

NASA Astrophysics Data System (ADS)

Reich, Daniel; Robbins, Mark; Leheny, Robert; Wonnell, Steven

2014-03-01

Over the past several years we have developed a two-semester second-year physics course sequence for students in the biosciences, tailored in part to the needs of undergraduate biophysics majors. One semester, ``Biological Physics,'' is based on the book of that name by P. Nelson. This talk will focus largely on the other semester, ``Wave Phenomena with Biophysical Applications,'' where we provide a novel introduction to the physics of waves, primarily through the study of experimental probes used in the biosciences that depend on the interaction of electromagnetic radiation with matter. Topic covered include: Fourier analysis, sound and hearing, diffraction - culminating in an analysis of x-ray fiber diffraction and its use in the determination of the structure of DNA - geometrical and physical optics, the physics of modern light microscopy, NMR and MRI. Laboratory exercises tailored to this course will also be described.

'Personalized medicine': what's in a name?

PubMed

Pokorska-Bocci, Anna; Stewart, Alison; Sagoo, Gurdeep S; Hall, Alison; Kroese, Mark; Burton, Hilary

2014-03-01

Over the last decade genomics and other molecular biosciences have enabled new capabilities that, according to many, have the potential to revolutionize medicine and healthcare. These developments have been associated with a range of terminologies, including 'precision', 'personalized', 'individualized' and 'stratified' medicine. In this article, based on a literature review, we examine how the terms have arisen and their various meanings and definitions. We discuss the impact of the new technologies on disease classification, prevention and management. We suggest that although genomics and molecular biosciences will undoubtedly greatly enhance the power of medicine, they will not lead to a conceptually new paradigm of medical care. What is new is the portfolio of modern tools that medicine and healthcare can use for better targeted approaches to health and disease management, and the sociopolitical contexts within which these tools are applied.

Diagnosis of Clostridium difficile-associated disease: examination of multiple algorithms using toxin EIA, glutamate dehydrogenase EIA and loop-mediated isothermal amplification.

PubMed

Bamber, A I; Fitzsimmons, K; Cunniffe, J G; Beasor, C C; Mackintosh, C A; Hobbs, G

2012-01-01

The laboratory diagnosis of Clostridium difficile infection (CDI) needs to be accurate and timely to ensure optimal patient management, infection control and reliable surveillance. Three methods are evaluated using 810 consecutive stool samples against toxigenic culture: CDT TOX A/B Premier enzyme immunoassay (EIA) kit (Meridian Bioscience, Europe), Premier EIA for C. difficile glutamate dehydrogenase (GDH) (Meridian Bioscience, Europe) and the Illumigene kit (Meridian Bioscience, Europe), both individually and within combined testing algorithms. The study revealed that the CDT TOX A/B Premier EIA gave rise to false-positive and false-negative results and demonstrated poor sensitivity (56.47%), compared to Premier EIA for C. difficile GDH (97.65%), suggesting this GDH EIA can be a useful negative screening method. Results for the Illumigene assay alone showed sensitivity, specificity, negative predictive value (NPV) and positive predictive value (PPV) of 91.57%, 98.07%, 99.03% and 84.44%, respectively. A two-stage algorithm using Premier EIA for C. difficile GDH/Illumigene assay yielded superior results compared with other testing algorithms (91.57%, 98.07%, 99.03% and 84.44%, respectively), mirroring the Illumigene performance. However, Illumigene is approximately half the cost of current polymerase chain reaction (PCR) methods, has a rapid turnaround time and requires no specialised skill base, making it an attractive alternative to assays such as the Xpert C. difficile assay (Cepheid, Sunnyvale, CA). A three-stage algorithm offered no improvement and would hamper workflow.

Integrating anticipated nutrigenomics bioscience applications with ethical aspects.

PubMed

Lévesque, Lise; Ozdemir, Vural; Gremmen, Bart; Godard, Béatrice

2008-03-01

Nutrigenomics is a subspecialty of nutrition science which aims to understand how gene-diet interactions influence individuals' response to food, disease susceptibility, and population health. Yet ethical enquiry into this field is being outpaced by nutrigenomics bioscience. The ethical issues surrounding nutrigenomics face the challenges of a rapidly evolving field which bring forward the additional dimension of crossdisciplinary integrative research between social and biomedical sciences. This article outlines the emerging nutrigenomics definitions and concepts and analyzes the existing ethics literature concerning personalized nutrition and presents "points to consider" over ethical issues regarding future nutrigenomics applications. The interest in nutrigenomics coincides with a shift in emphasis in medicine and biosciences toward prevention of future disease susceptibilities rather than treatment of already established disease. Hence, unique ethical issues emerge concerning the extent to which nutrigenomics can alter our relation to food, boundaries between health and disease, and the folklore of medical practice. Nutrigenomics can result in new social values, norms, and responsibilities for both individuals and societies. Nutrigenomics is not only another new application of "-omics" technologies in the context of gene-diet interactions. Nutrigenomics may fundamentally change the way we perceive human illness while shifting the focus and broadening the scope of health interventions from patients to healthy individuals. In resource- and time-limited healthcare settings, this creates unique ethical dilemmas and distributive justice issues. Ethical aspects of nutrigenomics applications should be addressed proactively, as this new science develops and increasingly coalesces with other applications of genomics in medicine and public health.

About the Barriers to Reaction of CCl4 with HFeOH and FeCl2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ginovska-Pangovska, Bojana; Camaioni, Donald M.; Dupuis, Michel

2011-08-11

The reactivity of iron nanoparticles in aqueous environments has received considerable attention due to their potential utilization in environmental remediation technologies. As part of a broader program aiming at an improved understanding of the mechanisms involved in the degradation of harmful chlorocarbons, joint experimental and computational studies of model systems were initiated. We previously reported on the reaction of one and two Fe atoms reactions with carbon tetrachloride (CCl4) in direct mimic of “atom-dropping” experiments, with insights into the formation of novel iron-carbon-chlorine complexes, their structures and possible reaction mechanisms. Increasing the level of complexity, we report here on themore » modeling of the reaction of HFeOH and CCl4 as companion research of recent ultra high vacuum experiments of the reaction of Fe with water and CCl4. HFeOH is a stable molecular species formed in the reaction of Fe with H2O. Experimentally the (Fe, H2O, CCl4) system showed no reactivity up to the desorption temperature of CCl4. Electron correlated CCSD(T) calculations (at DFT(B3LYP) optimized structures) indicated an energy barrier to reactivity of 24.5 kcal/mol following the formation of a stable ( 7.5 kcal/mol) long-range precursor complex. This finding is consistent with the lack of experimentally detected reaction products. This work was supported by the US Department of Energy Basic Energy Sciences' Chemical Sciences, Geosciences & Biosciences Division. Pacific Northwest National Laboratory is operated by Battelle for the US Department of Energy.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Petrik, Nikolay G.; Kimmel, Greg A.; Shen, Mingmin

Using temperature programmed desorption (TPD) and photon stimulated desorption (PSD), we show that coadsorbates of varying binding energies on the rutile TiO2(110) surface exert a commensurate inhibiting influence on the hole-mediated photodesorption of adsorbed O2. A variety of coadsorbates (Ar, Kr, Xe, N2, CO, CO2, CH4, N2O, acetone, methanol or water) were shown to quench O2 photoactivity, with the extent correlating with the coadsorbate’s gas phase basicity, which in turn determines the strength of the coadsorbate-Ti4+ bond. Coadsorbed rare gases inhibited the photodesorption of O2 by ~10-25%, whereas strongly bound species (water, methanol and acetone) nearly completely inhibited O2 PSD.more » We suggest that coadsorption of these molecules inhibit the arrival probability of holes to the surface. Band bending effects, which vary with the extent of charge transfer between the coadsorbate and the TiO2(110) surface, are not expected to be significant in the cases of the rare gases and physisorbed species. These results indicate that neutral coadsorbates can exert a significant influence on charge transfer events by altering the interfacial dipole in the vicinity of the target molecule. This work was supported by the US Department of Energy, Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences & Biosciences. The work was performed using EMSL, a national scientific user facility sponsored by the Department of Energy's Office of Biological and Environmental Research and located at Pacific Northwest National Laboratory (PNNL). PNNL is a multiprogram national laboratory operated for DOE by Battelle under Contract DE-AC05-76RL01830.« less

Effect of Graphene with Nanopores on Metal Clusters

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, Hu; Chen, Xianlang; Wang, Lei

Porous graphene, which is a novel type of defective graphene, shows excellent potential as a support material for metal clusters. In this work, the stability and electronic structures of metal clusters (Pd, Ir, Rh) supported on pristine graphene and graphene with different sizes of nanopore were investigated by first-principle density functional theory (DFT) calculations. Thereafter, CO adsorption and oxidation reaction on the Pd-graphene system were chosen to evaluate its catalytic performance. Graphene with nanopore can strongly stabilize the metal clusters and cause a substantial downshift of the d-band center of the metal clusters, thus decreasing CO adsorption. All binding energies,more » d-band centers, and adsorption energies show a linear change with the size of the nanopore: a bigger size of nanopore corresponds to a stronger metal clusters bond to the graphene, lower downshift of the d-band center, and weaker CO adsorption. By using a suitable size nanopore, supported Pd clusters on the graphene will have similar CO and O2 adsorption ability, thus leading to superior CO tolerance. The DFT calculated reaction energy barriers show that graphene with nanopore is a superior catalyst for CO oxidation reaction. These properties can play an important role in instructing graphene-supported metal catalyst preparation to prevent the diffusion or agglomeration of metal clusters and enhance catalytic performance. This work was supported by National Basic Research Program of China (973Program) (2013CB733501), the National Natural Science Foundation of China (NSFC-21176221, 21136001, 21101137, 21306169, and 91334013). D. Mei acknowledges the support from the US Department of Energy, Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences & Biosciences. Pacific Northwest National Laboratory (PNNL) is a multiprogram national laboratory operated for DOE by Battelle. Computing time was granted by the grand challenge of computational catalysis of the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) and by the National Energy Research Scientific Computing Center (NERSC).« less

Integrating standard operating procedures and industry notebook standards to evaluate students in laboratory courses.

PubMed

Wallert, Mark A; Provost, Joseph J

2014-01-01

To enhance the preparedness of graduates from the Biochemistry and Biotechnology (BCBT) Major at Minnesota State University Moorhead for employment in the bioscience industry we have developed a new Industry certificate program. The BCBT Industry Certificate was developed to address specific skill sets that local, regional, and national industry experts identified as lacking in new B.S. and B.A. biochemistry graduates. The industry certificate addresses concerns related to working in a regulated industry such as Good Laboratory Practices, Good Manufacturing Practices, and working in a Quality System. In this article we specifically describe how we developed a validation course that uses Standard Operating Procedures to describe grading policy and laboratory notebook requirements in an effort to better prepare students to transition into industry careers. © 2013 by The International Union of Biochemistry and Molecular Biology.

Frederick National Lab Collaboration Success Stories | FNLCR Staging

Cancer.gov

IBBR and Frederick National Lab Collaborate to Study Vaccine-Boosting Compounds The Frederick National Lab and the University of Maryland’s Institute for Bioscience and Biotechnology Research (IBBR) will work under a formal collaboration to eval

The Year In Science.

ERIC Educational Resources Information Center

Discover, 1984

1984-01-01

Highlights advances/discoveries (and scientists responsible for them) in various science areas during 1983: space science (shuttle flights, Russia); astronomy (infrared satellite, inflationary universe); physics (W/Z particles); chemistry (carbon bonding); environment (acid rain, dioxins, El Nino); bioscience (chemical signals); paleontology…

Helicos BioSciences.

PubMed

Milos, Patrice

2008-04-01

Helicos BioSciences Corporation is a life sciences company developing revolutionary new single molecule sequencing technology to provide the path to the US$1000 genome. True Single Molecule Sequencing (tSMS) will drive advancements in pharmacogenomics that can enable a better understanding of an individual's susceptibility to disease, develop more effective disease diagnoses and differentiate response to disease therapies. During 2007, genome-wide disease-association studies, the encylopedia of DNA elements (ENCODE) and the published genome sequence of two individuals have revealed human genome variation far more extensive than originally believed. These also demonstrated that common variations explain only a fraction of the genetic basis of disease. Therefore, the capability to understand an individual genome is critical in setting the foundation for the next great revolution in healthcare. Helicos is committed to this vision and will provide cost-effective genome sequencing and comprehensive analysis of the transcribed genome that can unlock the era of personalized healthcare.

On the outside looking in: redefining the role of analytical chemistry in the biosciences.

PubMed

Hare, Dominic J; New, Elizabeth J

2016-07-12

Biomedical research has moved on from the study of the structure of organs, cells and organelles. Today, the key questions that must be addressed to understand the body in health and disease are related to fundamental biochemistry: the distribution and speciation of chemicals, the regulation of chemical reactions, and the control of chemical environments. To see advances in this field, it is essential for analytical chemists to actively engage in this process, from beginning to end. In this Feature Article, we review the progress that has been made towards gaining an understanding of the chemistry of the body, while commenting on the intrinsic disconnect between new innovations in the field of analytical chemistry and practical application within the biosciences. We identify the challenges that prevent chemists from making a greater impact in this field, and highlight key steps for moving forward.

Conference scene: Select Biosciences Epigenetics Europe 2010.

PubMed

Razvi, Enal S

2011-02-01

The field of epigenetics is now on a geometric rise, driven in a large part by the realization that modifiers of chromatin are key regulators of biological processes in vivo. The three major classes of epigenetic effectors are DNA methylation, histone post-translational modifications (such as acetylation, methylation or phosphorylation) and small noncoding RNAs (most notably microRNAs). In this article, I report from Select Biosciences Epigenetics Europe 2010 industry conference held on 14-15 September 2010 at The Burlington Hotel, Dublin, Ireland. This industry conference was extremely well attended with a global pool of delegates representing the academic research community, biotechnology companies and pharmaceutical companies, as well as the technology/tool developers. This conference represented the current state of the epigenetics community with cancer/oncology as a key driver. In fact, it has been estimated that approximately 45% of epigenetic researchers today identify cancer/oncology as their main area of focus vis-à-vis their epigenetic research efforts.

Darwin v. 2.0: an interpreted computer language for the biosciences.

PubMed

Gonnet, G H; Hallett, M T; Korostensky, C; Bernardin, L

2000-02-01

We announce the availability of the second release of Darwin v. 2.0, an interpreted computer language especially tailored to researchers in the biosciences. The system is a general tool applicable to a wide range of problems. This second release improves Darwin version 1.6 in several ways: it now contains (1) a larger set of libraries touching most of the classical problems from computational biology (pairwise alignment, all versus all alignments, tree construction, multiple sequence alignment), (2) an expanded set of general purpose algorithms (search algorithms for discrete problems, matrix decomposition routines, complex/long integer arithmetic operations), (3) an improved language with a cleaner syntax, (4) better on-line help, and (5) a number of fixes to user-reported bugs. Darwin is made available for most operating systems free of char ge from the Computational Biochemistry Research Group (CBRG), reachable at http://chrg.inf.ethz.ch. darwin@inf.ethz.ch

Effect of Oxygen Defects on the Catalytic Performance of VOx/CeO2 Catalysts for Oxidative Dehydrogenation of Methanol

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Yan; Wei, Zhehao; Gao, Feng

2015-05-01

In this work, CeO2 nanocubes with controlled particle size and dominating (100) facets are synthesized as supports for VOx catalysts. Combined TEM, SEM, XRD, and Raman study reveals that the oxygen vacancy density of CeO2 supports can be tuned by tailoring the particle sizes without altering the dominating facets, where smaller particle sizes result in larger oxygen vacancy densities. At the same vanadium coverage, the VOx catalysts supported on small-sized CeO2 supports with higher oxygen defect densities exhibit promoted redox property and lower activation energy for methoxyl group decomposition, as evidenced by H2-TPR and methanol TPD study. These results furthermore » confirm that the presence of oxygen vacancies plays an important role in promoting the activity of VOx species in methanol oxidation. We gratefully acknowledge financial support from the U.S. Department of Energy (DOE), Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences, and Biosciences. Part of this work was conducted in the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL), a national scientific user facility sponsored by DOE’s Office of Biological and Environmental Research and located at Pacific Northwest National Laboratory (PNNL). PNNL is a multiprogram national laboratory operated for the DOE by Battelle.« less

Bacterial supersystem for alginate import/metabolism and its environmental and bioenergy applications.

PubMed

Hashimoto, Wataru; Kawai, Shigeyuki; Murata, Kousaku

2010-01-01

Distinct from most alginate-assimilating bacteria that secrete polysaccharide lyases extracellularly, a gram-negative bacterium, Sphingomonas sp. A1 (strain A1), can directly incorporate alginate into its cytoplasm, without degradation, through a "superchannel" consisting of a mouth-like pit on the cell surface, periplasmic binding proteins, and a cytoplasmic membrane-bound ATP-binding cassette transporter. Flagellin homologues function as cell surface alginate receptors essential for expressing the superchannel. Cytoplasmic alginate lyases with different substrate specificities and action modes degrade the polysaccharide to its constituent monosaccharides. The resultant monosaccharides, α-keto acids, are converted to a reduced form by NADPH-dependent reductase, and are finally metabolized in the TCA cycle. Transplantation of the strain A1 superchannel to xenobiotic-degrading sphingomonads enhances bioremediation through the propagation of bacteria with an elevated transport activity. Furthermore, strain A1 cells transformed with Zymomonas mobilis genes for pyruvate decarboxylase and alcohol dehydrogenase II produce considerable amounts of biofuel ethanol from alginate when grown statically. © 2010 Landes Bioscience

SERS study of riboflavin on green-synthesized silver nanoparticles prepared by reduction using different flavonoids: What is the role of flavonoid used?

NASA Astrophysics Data System (ADS)

Švecová, Marie; Ulbrich, Pavel; Dendisová, Marcela; Matějka, Pavel

2018-04-01

Spectroscopy of surface-enhanced Raman scattering (SERS) is nowadays widely used in the field of bio-science and medicine. These applications require new enhancing substrates with special properties. They should be non-toxic, environmentally friendly and (bio-) compatible with examined samples. Flavonoids are natural antioxidants with many positive effects on human health. Simultaneously, they can be used as reducing agent in preparation procedure of plasmonic enhancing substrate for SERS spectroscopy. The best amplifiers of Raman vibrational spectroscopic signal are generally silver nanoparticles (AgNPs). In this study, several flavonoids (forming a logical set) were used as reducing agent in AgNPs preparation procedures. Reactivity of 10 structurally arranged flavonoids (namely flavone, chrysin, apigenin, luteolin, tricetin, 3-hydroxyflavone, galangin, kaempferol, quercetin and myricetin) was compared and SERS-activity of prepared AgNPs was tested using model analyte riboflavin. Riboflavin was detected down to concentration 10-9 mol/l.

DOE Office of Scientific and Technical Information (OSTI.GOV)

van der Eide, Edwin F.; Yang, Ping; Walter, Eric D.

Unlike the very labile, unobservable radical cations [{l_brace}CpM(CO){sub 3}{r_brace}{sub 2}]{sup {sm_bullet}+} (M = W, Mo), derivatives [{l_brace}CpM(CO){sub 2}(PMe{sub 3}){r_brace}{sub 2}]{sup {sm_bullet}+} are stable enough to be isolated and characterized. Experimental and theoretical studies show that the shortened M-M bonds are of order 1 1/2, and that they are not supported by bridging ligands. The unpaired electron is fully delocalized, with a spin density of ca. 45% on each metal atom. We thank the U.S. Department of Energy (DOE), Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Biosciences and Geosciences for support of this work. Pacific Northwestmore » National Laboratory (PNNL) is a multiprogram national laboratory operated for DOE by Battelle. The EPR and computational studies were performed using EMSL, a national scientific user facility sponsored by the DOE's Office of Biological and Environmental Research and located at PNNL. We thank Dr. Charles Windisch for access to his UV-Vis-NIR spectrometer.« less

Advances in ultrasensitive mass spectrometry of organic molecules.

PubMed

Kandiah, Mathivathani; Urban, Pawel L

2013-06-21

Ultrasensitive mass spectrometric analysis of organic molecules is important for various branches of chemistry, and other fields including physics, earth and environmental sciences, archaeology, biomedicine, and materials science. It finds applications--as an enabling tool--in systems biology, biological imaging, clinical analysis, and forensics. Although there are a number of technical obstacles associated with the analysis of samples by mass spectrometry at ultratrace level (for example analyte losses during sample preparation, insufficient sensitivity, ion suppression), several noteworthy developments have been made over the years. They include: sensitive ion sources, loss-free interfaces, ion optics components, efficient mass analyzers and detectors, as well as "smart" sample preparation strategies. Some of the mass spectrometric methods published to date can achieve sensitivity which is by several orders of magnitude higher than that of alternative approaches. Femto- and attomole level limits of detection are nowadays common, while zepto- and yoctomole level limits of detection have also been reported. We envision that the ultrasensitive mass spectrometric assays will soon contribute to new discoveries in bioscience and other areas.

Lensless high-resolution on-chip optofluidic microscopes for Caenorhabditis elegans and cell imaging

PubMed Central

Cui, Xiquan; Lee, Lap Man; Heng, Xin; Zhong, Weiwei; Sternberg, Paul W.; Psaltis, Demetri; Yang, Changhuei

2008-01-01

Low-cost and high-resolution on-chip microscopes are vital for reducing cost and improving efficiency for modern biomedicine and bioscience. Despite the needs, the conventional microscope design has proven difficult to miniaturize. Here, we report the implementation and application of two high-resolution (≈0.9 μm for the first and ≈0.8 μm for the second), lensless, and fully on-chip microscopes based on the optofluidic microscopy (OFM) method. These systems abandon the conventional microscope design, which requires expensive lenses and large space to magnify images, and instead utilizes microfluidic flow to deliver specimens across array(s) of micrometer-size apertures defined on a metal-coated CMOS sensor to generate direct projection images. The first system utilizes a gravity-driven microfluidic flow for sample scanning and is suited for imaging elongate objects, such as Caenorhabditis elegans; and the second system employs an electrokinetic drive for flow control and is suited for imaging cells and other spherical/ellipsoidal objects. As a demonstration of the OFM for bioscience research, we show that the prototypes can be used to perform automated phenotype characterization of different Caenorhabditis elegans mutant strains, and to image spores and single cellular entities. The optofluidic microscope design, readily fabricable with existing semiconductor and microfluidic technologies, offers low-cost and highly compact imaging solutions. More functionalities, such as on-chip phase and fluorescence imaging, can also be readily adapted into OFM systems. We anticipate that the OFM can significantly address a range of biomedical and bioscience needs, and engender new microscope applications. PMID:18663227

Expansion of genetic testing in the division of functional genomics, research center for bioscience and technology, tottori university from 2000 to 2013.

PubMed

Adachi, Kaori

2014-03-01

At the Division of Functional Genomics, Research Center for Bioscience and Technology, Tottori University, we have been making an effort to establish a genetic testing facility that can provide the same screening procedures conducted worldwide. Direct Sequencing of PCR products is the main method to detect point mutations, small deletions and insertions. Multiplex Ligation-dependent Probe Amplification (MLPA) was used to detect large deletions or insertions. Expansion of the repeat was analyzed for triplet repeat diseases. Original primers were constructed for 41 diseases when the reported primers failed to amplify the gene. Prediction of functional effects of human nsSNPs (PolyPhen) was used for evaluation of novel mutations. From January 2000 to September 2013, a total of 1,006 DNA samples were subjected to genetic testing in the Division of Functional Genomics, Research Center for Bioscience and Technology, Tottori University. The hospitals that requested genetic testing were located in 43 prefectures in Japan and in 11 foreign countries. The genetic testing covered 62 diseases, and mutations were detected in 287 out of 1,006 with an average mutation detection rate of 24.7%. There were 77 samples for prenatal diagnosis. The number of samples has rapidly increased since 2010. In 2013, the next-generation sequencers were introduced in our facility and are expected to provide more comprehensive genetic testing in the near future. Nowadays, genetic testing is a popular and powerful tool for diagnosis of many genetic diseases. Our genetic testing should be further expanded in the future.

Reflective writing as a tool for assessing teamwork in bioscience: insights into student performance and understanding of teamwork.

PubMed

Mayne, Lynne

2012-07-01

To ensure a modern bioscience curriculum that responds to the current needs of stakeholders, there is a need to embed a range of generic capabilities that enables graduates to succeed in and contribute to a rapidly changing world, as well as building strong bioscience skills and knowledge. The curriculum must also prepare students for a rapidly evolving competitive work place and align with the needs of industry. This creates a challenge, how do we develop generic capabilities without losing discipline content. This report analyses teamwork projects embedded in an undergraduate Biotechnology degree designed to promote teamwork skills along with a deeper understanding of the underpinning biochemistry. Student reflective writing was used to capture students' understanding and experience of teamwork as well as provide insight into their metacognition. The analysis demonstrates that 73% of Year 3 and 93% of Year 4 students were capable of learning about teamwork through reflective writing. While the importance of frequent high quality communication was a common theme, evidence suggests that many students were unsophisticated in their use of communication software. The analysis also highlighted the depth of metacognition that underpins successful team function and the significant weaknesses in self-insight some students possess. These findings challenge assumptions regarding student capacity for leadership and the ability of some students to contribute to successful team outcomes. It is essential for the design of teamwork experiences to fully understand the competencies that underlie teamwork, the metacognitive processes required, and ensure that assessments are fair and measure individual academic performance. Copyright © 2012 Wiley Periodicals, Inc.

The use of team-based, guided inquiry learning to overcome educational disadvantages in learning human physiology: a structural equation model.

PubMed

Rathner, Joseph A; Byrne, Graeme

2014-09-01

The study of human bioscience is viewed as a crucial curriculum in allied health. Nevertheless, bioscience (and particularly physiology) is notoriously difficult for undergraduates, particularly academically disadvantaged students. So endemic are the high failure rates (particularly in nursing) that it has come to be known as "the human bioscience problem." In the present report, we describe the outcomes for individual success in studying first-year human physiology in a subject that emphasises team-based active learning as the major pedagogy for mastering subject learning outcomes. Structural equation modeling was used to develop a model of the impact team learning had on individual performance. Modeling was consistent with the idea that students with similar academic abilities (as determined by tertiary entrance rank) were advantaged (scored higher on individual assessment items) by working in strong teams (teams that scored higher in team-based assessments). Analysis of covariance revealed that students who studied the subject with active learning as the major mode of learning activities outperformed students who studied the subject using the traditional didactic teaching format (lectures and tutorials, P = 0.000). After adjustment for tertiary entrance rank (via analysis of covariance) on two individual tests (the final exam and a late-semester in-class test), individual student grades improved by 8% (95% confidence interval: 6-10%) and 12% (95% confidence interval: 10-14%) when students engaged in team-based active learning. These data quantitatively support the notion that weaker students working in strong teams can overcome their educational disadvantages. Copyright © 2014 The American Physiological Society.

Carbon Nanotube Membranes for Water Purification

NASA Astrophysics Data System (ADS)

Bakajin, Olgica

2009-03-01

Carbon nanotubes are an excellent platform for the fundamental studies of transport through channels commensurate with molecular size. Water transport through carbon nanotubes is also believed to be similar to transport in biological channels such as aquaporins. I will discuss the transport of gas, water and ions through microfabricated membranes with sub-2 nanometer aligned carbon nanotubes as ideal atomically-smooth pores. The measured gas flow through carbon nanotubes exceeded predictions of the Knudsen diffusion model by more than an order of magnitude. The measured water flow exceeded values calculated from continuum hydrodynamics models by more than three orders of magnitude and is comparable to flow rates extrapolated from molecular dynamics simulations and measured for aquaporins. More recent reverse osmosis experiments reveal ion rejection by our membranes. Based on our experimental findings, the current understanding of the fundamentals of water and gas transport and of ion rejection will be discussed. The potential application space that exploits these unique nanofluidic phenomena will be explored. The extremely high permeabilities of these membranes, combined with their small pore size will enable energy efficient filtration and eventually decrease the cost of water purification.[4pt] In collaboration with Francesco Fornasiero, Biosciences and Biotechnology Division, PLS, LLNL, Livermore, CA 94550; Sangil Kim, NSF Center for Biophotonics Science & Technology, University of California at Davis, Sacramento CA 95817; Jung Bin In, Mechanical Engineering Department, UC Berkeley, Berkeley CA 94720; Hyung Gyu Park, Jason K Holt, and Michael Stadermann, Biosciences and Biotechnology Division, PLS, LLNL; Costas P. Grigoropoulos, Mechanical Engineering Department, UC Berkeley; Aleksandr Noy, Biosciences and Biotechnology Division, PLS, LLNL and School of Natural Sciences, University of California at Merced.

The use of team-based, guided inquiry learning to overcome educational disadvantages in learning human physiology: a structural equation model

PubMed Central

Byrne, Graeme

2014-01-01

The study of human bioscience is viewed as a crucial curriculum in allied health. Nevertheless, bioscience (and particularly physiology) is notoriously difficult for undergraduates, particularly academically disadvantaged students. So endemic are the high failure rates (particularly in nursing) that it has come to be known as “the human bioscience problem.” In the present report, we describe the outcomes for individual success in studying first-year human physiology in a subject that emphasises team-based active learning as the major pedagogy for mastering subject learning outcomes. Structural equation modeling was used to develop a model of the impact team learning had on individual performance. Modeling was consistent with the idea that students with similar academic abilities (as determined by tertiary entrance rank) were advantaged (scored higher on individual assessment items) by working in strong teams (teams that scored higher in team-based assessments). Analysis of covariance revealed that students who studied the subject with active learning as the major mode of learning activities outperformed students who studied the subject using the traditional didactic teaching format (lectures and tutorials, P = 0.000). After adjustment for tertiary entrance rank (via analysis of covariance) on two individual tests (the final exam and a late-semester in-class test), individual student grades improved by 8% (95% confidence interval: 6–10%) and 12% (95% confidence interval: 10–14%) when students engaged in team-based active learning. These data quantitatively support the notion that weaker students working in strong teams can overcome their educational disadvantages. PMID:25179611

Overview of the immune response to phytonutrient in poultry

USDA-ARS?s Scientific Manuscript database

Overview of the immune response to phytonutrient in poultry. Lillehoj, Hyun S. Animal Biosciences and Biotechnology Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service, USDA, Beltsville, MD 20705, USA Phytochemicals are non-nutritive, plant-derived chemicals, many w...

75 FR 47549 - Foreign-Trade Zone 119 - Minneapolis, Minnesota, Site Renumbering Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-06

...)--Chaska Bio-Science Corporate Campus, located at the intersection of Carver County Road 10 and New U.S. Highway 212, Chaska (sunset provision - June 30, 2017); Site 8 (200 acres)--Elk Run Bio-Business Park...

The role biomedical science laboratories can play in improving science knowledge and promoting first-year nursing academic success

NASA Astrophysics Data System (ADS)

Arneson, Pam

The Role Biomedical Science Laboratories Can Play In Improving Science Knowledge and Promoting First-Year Nursing Academic Success The need for additional nursing and health care professionals is expected to increase dramatically over the next 20 years. With this in mind, students must have strong biomedical science knowledge to be competent in their field. Some studies have shown that participation in bioscience laboratories can enhance science knowledge. If this is true, an analysis of the role bioscience labs have in first-year nursing academic success is apposite. In response, this study sought to determine whether concurrent enrollment in anatomy and microbiology lecture and lab courses improved final lecture course grades. The investigation was expanded to include a comparison of first-year nursing GPA and prerequisite bioscience concurrent lecture/lab enrollment. Additionally, research has indicated that learning is affected by student perception of the course, instructor, content, and environment. To gain an insight regarding students' perspectives of laboratory courses, almost 100 students completed a 20-statement perception survey to understand how lab participation affects learning. Data analyses involved comparing anatomy and microbiology final lecture course grades between students who concurrently enrolled in the lecture and lab courses and students who completed the lecture course alone. Independent t test analyses revealed that there was no significant difference between the groups for anatomy, t(285) = .11, p = .912, but for microbiology, the lab course provided a significant educational benefit, t(256) = 4.47, p = .000. However, when concurrent prerequisite bioscience lecture/lab enrollment was compared to non-concurrent enrollment for first-year nursing GPA using independent t test analyses, no significant difference was found for South Dakota State University, t(37) = -1.57, p = .125, or for the University of South Dakota, t(38) = -0.46, p = .651. Student perception survey examination included computation of means and standard deviations for statements related to the educational importance of lab courses, the value of lab experimentation, and the usefulness of concurrent lecture/lab enrollment. Independent t test analyses sought to determine differences within the courses of anatomy lab and microbiology lab as well as differences between the instructors involved. Results suggested that student perceptions may be dependent on the course, the instructor, and possibly the content.

Environmentally Benign and Permanent Modifications to Prevent Biofouling on Marine and Hydrokinetic Devices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zheng Zhang

2012-04-19

Semprus Biosciences is developing environmentally benign and permanent modifications to prevent biofouling on Marine and Hydrokinetic (MHK) devices. Biofouling, including growth on external surfaces by bacteria, algae, barnacles, mussels, and other marine organisms, accumulate quickly on MHK devices, causing mechanical wear and changes in performance. Biofouling on crucial components of hydrokinetic devices, such as rotors, generators, and turbines, imposes substantial mass and hydrodynamic loading with associated efficiency loss and maintenance costs. Most antifouling coatings leach toxic ingredients, such as copper and tributyltin, through an eroding process, but increasingly stringent regulation of biocides has led to interest in the development ofmore » non-biocidal technologies to control fouling. Semprus Biosciences research team is developing modifications to prevent fouling from a broad spectrum of organisms on devices of all shapes, sizes, and materials for the life of the product. The research team designed and developed betaine-based polymers as novel underwater coatings to resist the attachment of marine organisms. Different betaine-based monomers and polymers were synthesized and incorporated within various coating formulations. The formulations and application methods were developed on aluminum panels with required adhesion strength and mechanical properties. The coating polymers were chemically stable under UV, hydrolytic and oxidative environments. The sulfobetaine formulations are applicable as nonleaching and stable underwater coatings. For the first time, coating formulations modified with highly packed sulfobetaine polymers were prepared and demonstrated resistance to a broad spectrum of marine organisms. Assays for comparing nonfouling performance were developed to evaluate protein adsorption and bacteria attachment. Barnacle settlement and removal were evaluated and a 60-day field test was performed. Silicone substrates including a commercial fouling release coating were used for comparison. Compared with the unmodified silicone substrates, the sulfobetaine-modified formulations were able to exhibit a 98% reduction in fibrinogen adsorption, 97.0% (E. coli), 99.6% (S. aureus), and 99.5% (C. lytica) reduction in bacteria attachment, and 100% reduction in barnacles cyprid attachment. In addition to the significant improvement in fouling resistance of various organisms, the 60-day field test also showed an evident efficacy from visual assessment, foul rating, and fouling removal test. The research confirmed that the novel antifouling mechanism of betaine polymers provides a new avenue for marine coating development. The developed coatings out-performed currently used nontoxic underwater coatings in a broad spectrum of fouling resistance. By further developing formulations and processing methods for specific devices, the technology is ready for the next stage of development with demonstration in MHK systems.« less

KSC-07pd3516

NASA Image and Video Library

2007-12-03

KENNEDY SPACE CENTER, FLA. -- After the mission STS-122 crew's arrival at NASA's Kennedy Space Center, Mission Specialist Hans Schlegel is introduced during a media opportunity on the Shuttle Landing Facility. Schlegel represents the European Space Agency. The crew's arrival signals the imminent launch of space shuttle Atlantis on mission STS-122. The launch countdown begins at 7 p.m. Dec. 3. Launch is scheduled for 4:31 p.m. EST on Dec. 6. Atlantis will carry the Columbus Lab, Europe's largest contribution to the construction of the International Space Station. It will support scientific and technological research in a microgravity environment. Columbus, a program of ESA, is a multifunctional, pressurized laboratory that will be permanently attached to Node 2 of the space station to carry out experiments in materials science, fluid physics and biosciences, as well as to perform a number of technological applications. Photo credit: NASA/Kim Shiflett

KSC-07pd3511

NASA Image and Video Library

2007-12-03

KENNEDY SPACE CENTER, FLA. -- Center Director Bill Parsons welcomes STS-122 Mission Specialist Rex Walheim after the mission crew's arrival at NASA's Kennedy Space Center. Behind Walheim are Mission Specialists Hans Schlegel and Stanley Love. Schlegel represents the European Space Agency. The crew's arrival signals the imminent launch of space shuttle Atlantis on mission STS-122. The launch countdown begins at 7 p.m. Dec. 3. Launch is scheduled for 4:31 p.m. EST on Dec. 6. Atlantis will carry the Columbus Lab, Europe's largest contribution to the construction of the International Space Station. It will support scientific and technological research in a microgravity environment. Columbus, a program of ESA, is a multifunctional, pressurized laboratory that will be permanently attached to Node 2 of the space station to carry out experiments in materials science, fluid physics and biosciences, as well as to perform a number of technological applications. Photo credit: NASA/Kim Shiflett

Coherent Control About a Conical Intersection

NASA Astrophysics Data System (ADS)

Liekhus-Schmaltz, Chelsea; McCracken, Gregory; Kaldun, Andreas; Cryan, James P.; Bucksbaum, Philip H.

2017-04-01

Conical intersections (CIs) are degeneracies between molecular potential energy surfaces that occur in essentially all molecules with more than three atoms. Many studies have established that CIs allow for non-Born-Oppenheimer (non-adiabatic) molecular dynamics. In addition, CIs have many useful attributes for coherent control that have not been fully studied. Here we demonstrate two modes of control around a CI that make use of these properties. The first method uses a continuous light field, resonant absorption, and stimulated emission to control the population on two intersecting electronic states. The second method uses a pulsed light field and the geometric phase accumulated by a wavepacket traversing a CI to control the shape of the wavepacket. This work was supported by the National Science Foundation under Grant No. PHY-0649578, the DOE SCGSR fellowship program, and the DOE, Office of Science, BES, Chemical Sciences, Geosciences, and Biosciences Division.

Alternative interpretations of oil spill data

USGS Publications Warehouse

Piatt, John F.

1997-01-01

In his article "Oil, Seabirds, and Science" (BioScience 46: 587-597), John Wiens attempted to review Exxon Valdez oil spill (EVOS) damage assessment studies and the politics of EVOS science in one stroke. In my opinion, neither purpose was particularly well served.

Establishment of Maximum Voluntary Compressive Neck Tolerance Levels

DTIC Science & Technology

2011-07-01

Bridges Casey Pirnstill Chris Burneka John Plaga Grant Roush Biosciences and Performance Division Vulnerability Analysis Branch July 2011...S) Michael Cote, John Buhrman, Nathaniel Bridges, Casey Pirnstill, Chris Burneka, John Plaga , Grant Roush 5d. PROJECT NUMBER OSMS 5e. TASK

Multi-Variant/Capability Next Generation Troop Seat (M-V/C NGTS)

DTIC Science & Technology

2009-01-01

John Plaga , Work Unit Manager MARK M. HOFFMAN Deputy Chief Biomechanics Branch Biosciences and Protection Division Human...John A. Plaga a. REPORT U b. ABSTRACT U c. THIS PAGE U SAR 20 19b. TELEPHONE NUMBER (include area

Wei Wang | NREL

Science.gov Websites

Research Interests Yeast strain development for production of hydrocarbon via metabolic engineering CBP Research Scientist, National Renewable Energy Laboratory, Bioscience Center, 2009-present Postdoctoral Research Fellow, Auburn University, Chemical Engineering Department, Y.Y. Lee's group Research Scientist

Sandia National Laboratories: Careers: Hiring Process

Science.gov Websites

Suppliers iSupplier Account Accounts Payable Contract Information Construction & Facilities Contract Foundations Bioscience Computing & Information Science Electromagnetics Engineering Science Geoscience notifications. Visit our Careers tool to search for jobs and register for an account. Registering will enable

Tackling the Triple-Threat Genome of Miscanthus x giganteus (2010 JGI User Meeting)

ScienceCinema

Moose, Steve

2018-02-05

Steve Moose from the University of Illinois at Urbana-Champaign and the Energy Biosciences Institute on "Tackling the Triple-Threat Genome of Miscanthus x giganteus" on March 25, 2010 at the 5th Annual DOE JGI User Meeting.

The draft genome of Globodera ellingtonae

USDA-ARS?s Scientific Manuscript database

Globodera ellingtonae is a newly described potato cyst nematode found in Idaho, Oregon, and Argentina. Here we present a genome assembly for G. ellingtonae, a relative of the quarantine nematodes G. pallida and G. rostochiensis, produced using data from Illumina and Pacific Biosciences sequencing te...

Tackling the Triple-Threat Genome of Miscanthus x giganteus (2010 JGI User Meeting)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moose, Steve

2010-03-25

Steve Moose from the University of Illinois at Urbana-Champaign and the Energy Biosciences Institute on "Tackling the Triple-Threat Genome of Miscanthus x giganteus" on March 25, 2010 at the 5th Annual DOE JGI User Meeting.

Comparison of Document Data Bases

ERIC Educational Resources Information Center

Schipma, Peter B.; And Others

This paper presents a detailed analysis of the content and format of seven machine-readable bibliographic data bases: Chemical Abstracts Service Condensates, Chemical and Biological Activities, and Polymer Science and Technology, Biosciences Information Service's BA Previews including Biological Abstracts and BioResearch Index, Institute for…

Francis Crick, cross-worlds influencer: A narrative model to historicize big bioscience

PubMed Central

Aicardi, Christine

2016-01-01

The essay is an empirical case study of famed British scientist Francis Crick. Viewing him as a ‘cross-worlds influencer’ who was moreover dedicated to a cause, I have tried to understand how these two characteristics influenced the trajectory of his long career and how they shaped his contributions to the diverse research fields in which he was active, and concluded that these characteristics reconfigure Crick's career into a coherent whole. First, I identify a major thread running through Crick's career: helping organise ‘un-disciplined’ new research fields, and show that his successive choices were not serendipitous but motivated by what he construed as a crusade against ‘vitalism’: anti-vitalism was a defining driver of his career. I then examine how Crick put his skills as a crossworlds influencer to the service of his cause, by helping organise his chosen fields of intervention. I argue that his activities as a cross-worlds influencer were an integral part of his way of ‘doing science’ and that his contributions to science, neuroscience in particular, should be re-evaluated in this light. This leads me to advance a possible strategy for historians to investigate big bioscience fields. Following Abir-Am, I propose to trace their genealogies back to the fluctuating semi-institutional gatherings and the institutional structures that sustained them. My research on Crick supports the view that such studies can bring insights into the question of why the contours of contemporary big bioscience endeavours have come to be shaped the way they are. Further, the essay provides a heuristic device for approaching these enquiries: ‘follow the cross-worlds influencers’ who worked to build and organise these semi-institutional gatherings and institutional structures. PMID:26383132

Francis Crick, cross-worlds influencer: A narrative model to historicize big bioscience.

PubMed

Aicardi, Christine

2016-02-01

The essay is an empirical case study of famed British scientist Francis Crick. Viewing him as a 'cross-worlds influencer' who was moreover dedicated to a cause, I have tried to understand how these two characteristics influenced the trajectory of his long career and how they shaped his contributions to the diverse research fields in which he was active, and concluded that these characteristics reconfigure Crick's career into a coherent whole. First, I identify a major thread running through Crick's career: helping organise 'un-disciplined' new research fields, and show that his successive choices were not serendipitous but motivated by what he construed as a crusade against 'vitalism': anti-vitalism was a defining driver of his career. I then examine how Crick put his skills as a crossworlds influencer to the service of his cause, by helping organise his chosen fields of intervention. I argue that his activities as a cross-worlds influencer were an integral part of his way of 'doing science' and that his contributions to science, neuroscience in particular, should be re-evaluated in this light. This leads me to advance a possible strategy for historians to investigate big bioscience fields. Following Abir-Am, I propose to trace their genealogies back to the fluctuating semi-institutional gatherings and the institutional structures that sustained them. My research on Crick supports the view that such studies can bring insights into the question of why the contours of contemporary big bioscience endeavours have come to be shaped the way they are. Further, the essay provides a heuristic device for approaching these enquiries: 'follow the cross-worlds influencers' who worked to build and organise these semi-institutional gatherings and institutional structures. Copyright © 2015 The Author. Published by Elsevier Ltd.. All rights reserved.

Embedded academic writing support for nursing students with English as a second language.

PubMed

Salamonson, Yenna; Koch, Jane; Weaver, Roslyn; Everett, Bronwyn; Jackson, Debra

2010-02-01

This paper reports a study which evaluated a brief, embedded academic support workshop as a strategy for improving academic writing skills in first-year nursing students with low-to-medium English language proficiency. Nursing students who speak English as a second language have lower academic success compared with their native English-speaking counterparts. The development of academic writing skills is known to be most effective when embedded into discipline-specific curricula. Using a randomized controlled design, in 2008 106 students pre-enrolled in an introductory bioscience subject were randomized to receive either the intervention, a 4-day embedded academic learning support workshop facilitated by two bioscience (content) nursing academics and a writing and editing professional, or to act as the control group. The primary focus of the workshop was to support students to work through a mock assignment by providing progressive feedback and written suggestions on how to improve their answers. Of the 59 students randomized to the intervention, only 28 attended the workshop. Bioscience assignment results were analysed for those who attended (attendees), those randomized to the intervention but who did not attend (non-attendees), and the control group. Using anova, the results indicated that attendees achieved statistically significantly higher mean scores (70.8, sd: 6.1) compared to both control group (58.4, sd: 3.4, P = 0.002) and non-attendees (48.5, sd: 5.5, P = 0.001). A brief, intensive, embedded academic support workshop was effective in improving the academic writing ability of nursing students with low-to-medium English language proficiency, although reaching all students who are likely to benefit from this intervention remains a challenge.

Novel full-length major histocompatibility complex class I allele discovery and haplotype definition in pig-tailed macaques.

PubMed

Semler, Matthew R; Wiseman, Roger W; Karl, Julie A; Graham, Michael E; Gieger, Samantha M; O'Connor, David H

2018-06-01

Pig-tailed macaques (Macaca nemestrina, Mane) are important models for human immunodeficiency virus (HIV) studies. Their infectability with minimally modified HIV makes them a uniquely valuable animal model to mimic human infection with HIV and progression to acquired immunodeficiency syndrome (AIDS). However, variation in the pig-tailed macaque major histocompatibility complex (MHC) and the impact of individual transcripts on the pathogenesis of HIV and other infectious diseases is understudied compared to that of rhesus and cynomolgus macaques. In this study, we used Pacific Biosciences single-molecule real-time circular consensus sequencing to describe full-length MHC class I (MHC-I) transcripts for 194 pig-tailed macaques from three breeding centers. We then used the full-length sequences to infer Mane-A and Mane-B haplotypes containing groups of MHC-I transcripts that co-segregate due to physical linkage. In total, we characterized full-length open reading frames (ORFs) for 313 Mane-A, Mane-B, and Mane-I sequences that defined 86 Mane-A and 106 Mane-B MHC-I haplotypes. Pacific Biosciences technology allows us to resolve these Mane-A and Mane-B haplotypes to the level of synonymous allelic variants. The newly defined haplotypes and transcript sequences containing full-length ORFs provide an important resource for infectious disease researchers as certain MHC haplotypes have been shown to provide exceptional control of simian immunodeficiency virus (SIV) replication and prevention of AIDS-like disease in nonhuman primates. The increased allelic resolution provided by Pacific Biosciences sequencing also benefits transplant research by allowing researchers to more specifically match haplotypes between donors and recipients to the level of nonsynonymous allelic variation, thus reducing the risk of graft-versus-host disease.

Impact of zeolite aging in hot liquid water on activity for acid-catalyzed dehydration of alcohols

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vjunov, Aleksei; Derewinski, Miroslaw A.; Fulton, John L.

The catalytic performance of zeolite in aqueous medium depends on a multitude of factors, such as the concentration and distribution of active sites and framework integrity. Al K–edge extended X–ray absorption fine structure and 27Al MAS NMR spectroscopies in combination with DFT calculations are used to determine the distribution of tetrahedral Al sites both qualitatively and quantitatively for both parent and 48 h 160 ºC water treated HBEA catalysts. There is no evidence of Al coordination modification after aging in water. The distribution and concentration of Al T–sites, active centers for the dehydration of cyclohexanol, do not markedly impact themore » catalytic performance in water, because the Brønsted acidic protons are present in the form of hydrated hydronium ions and thus have very similar acid properties. The results suggest that all Brønsted acid sites are equally active in aqueous medium. The decrease of zeolite catalytic performance after water treatment is attributed to the reduced concentration of Brønsted acid sites. Increasing the stability of pore walls and decreasing the rate of Si–O–Si group hydrolysis may result in improved apparent zeolite catalytic performance in aqueous medium. Authors thank B. W. Arey (PNNL) for HIM measurements, T. Huthwelker for support during Al XAFS measurements at the Swiss Light Source (PSI, Switzerland), J. Z. Hu and S. D. Burton (PNNL) for support during NMR experiments. This work was supported by the U. S. Department of Energy (DOE), Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences & Biosciences. MD acknowledges support by the Materials Synthesis and Simulation Across Scales (MS3 Initiative) conducted under Laboratory Directed Research & Development Program at PNNL. HIM imaging and NMR experiments were performed at the Environmental Molecular Sciences Laboratory, a national scientific user facility sponsored by the DOE Office of Science, Office of Biological and Environmental Research, located at Pacific Northwest National Laboratory (PNNL). PNNL is a multiprogram national laboratory operated for the DOE by Battelle Memorial Institute under contract # DE-AC05-76RL0-1830« less

ic-cmtp3: 3rd International Conference on Competitive Materials and Technology Processes

NASA Astrophysics Data System (ADS)

2016-04-01

Competitiveness is one of the most important factors in our lives and it plays a key role in the efficiency both of organizations and societies. The more scientifically advanced and prepared organizations develop more competitive materials with better physical, chemical, and biological properties, and the leading companies apply more competitive equipment and technological processes. The aims of the 3rd International Conference on Competitive Materials and Technology Processes (ic-cmtp3), and the 1st International Symposium on Innovative Carbons and Carbon Based Materials (is-icbm1) and the 1st International Symposium on Innovative Construction Materials (is-icm1) organized alongside are the following: —Promote new methods and results of scientific research in the fields of material, biological, environmental and technological sciences; —Exchange information between the theoretical and applied sciences as well as technical and technological implementations; —Promote communication and collaboration between the scientists, researchers and engineers of different nations, countries and continents. Among the major fields of interest are advanced and innovative materials with competitive characteristics, including mechanical, physical, chemical, biological, medical and thermal, properties and extreme dynamic strength. Their crystalline, nano - and micro-structures, phase transformations as well as details of their technological processes, tests and measurements are also in the focus of the ic-cmtp3 conference and the is-scbm1 and is-icm1 symposia. Multidisciplinary applications of material science and the technological problems encountered in sectors like ceramics, glasses, thin films, aerospace, automotive and marine industries, electronics, energy, construction materials, medicine, biosciences and environmental sciences are of particular interest. In accordance with the program of the ic-cmtp3 conference and is-icbm1 and is-icm1 symposia we have received more than 350 enquiries and registrations from different organizations. More than 240 abstracts were accepted for presentation. From them 12 were plenary lectures and 112 oral presentations. Researchers from 41 countries in Asia, Europe, Africa, North and South America travelled to Miskolc-Lillafüred (Hungary) and participated in the conference events. Including co-authors, the research work of more than 700 scientists were presented in the sessions and symposia of the ic-cmtp3 conference.

Comparison of the Photodesorption Activities of cis-Butene, trans-Butene and Isobutene on the Rutile TiO 2(110) Surface

DOE Office of Scientific and Technical Information (OSTI.GOV)

Henderson, Michael A.

2013-10-17

The chemical and photochemical properties of three butene molecules (cis-butene, trans-butene and isobutene) were explored on the clean rutile TiO 2(110) surface using temperature programmed desorption (TPD) and photon simulated desorption (PSD). At the low coverage limit, trans-butene was the most strongly bound butene on the TiO 2(110) surface, desorbing at ~ 210 K, however increased intermolecular repulsions between trans-butene molecules at higher coverage diminished its binding. Both cis-butene and isobutene saturated the first layer on TiO 2(110) at a coverage of ~0.50 ML in a single TPD feature at 184 and 192 K, respectively. In contrast, the maximum coveragemore » that trans-butene could achieve in its 210 K peak was ~1/3 ML, with higher coverages resulting a low temperature desorption at ~137 K. Coverages of these molecules above 0.50 ML resulted in population of second layer and multilayer states. The instability of trans-butene at a coverage of 0.5 ML on the surface was linked to the inversion center in its symmetry. In the absence of coadsorbed oxygen, the primary photochemical pathway of each butene molecule on TiO 2(110) was photodesorption. The photoactivities of these molecules on TiO 2(110) at an initial coverage of 0.50 ML followed the trend: isobutene > cis-butene > trans-butene. In contrast, the photoactivities of low coverages of cis-butene and trans-butene exceeded those measured at 0.50 ML. These data suggest that intermolecular interactions (repulsions) play a significant role in diminishing the photoactivities of weakly bound molecules on TiO 2 photocatalysts. Work reported here was supported by the U.S. Department of Energy, Office of Basic Energy Science, Division of Chemical Sciences, Geosciences, and Biosciences, and performed in the Williams R. Wiley Environmental Molecular Science Laboratory (EMSL), a Department of Energy user facility funded by the Office of Biological and Environmental Research. Pacific Northwest National Laboratory is a multiprogram national laboratory operated for the U.S. Department of Energy by the Battelle Memorial Institute under contract DEAC05-76RL01830.« less

IBBR and Frederick National Lab Collaborate to Study Vaccine-Boosting Compounds | FNLCR Staging

Cancer.gov

The Frederick National Lab and the University of Maryland’s Institute for Bioscience and Biotechnology Research (IBBR) will work under a formal collaboration to evaluate the effectiveness of new compounds that might be used to enhance the immune re

CEE-ing is believing

PubMed Central

Lamb, Katrina

2011-01-01

Bioscience ventures in Central and Eastern Europe are becoming a presence in world healthcare markets despite a perennially short supply of venture funding and other support mechanisms relative to other world economic regions. Here are three up-and-coming CEE stories worth keeping an eye on. PMID:21869613

Digitizing and Securing Archived Laboratory Notebooks

ERIC Educational Resources Information Center

Caporizzo, Marilyn

2008-01-01

The Information Group at Millipore has been successfully using a digital rights management tool to secure the email distribution of archived laboratory notebooks. Millipore is a life science leader providing cutting-edge technologies, tools, and services for bioscience research and biopharmaceutical manufacturing. Consisting of four full-time…

75 FR 71697 - Pesticide Products; Registration Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-24

...: MacIntosh and Associates, Inc., 1203 Hartford Avenue, Saint Paul, MN 55116-1622 (on behalf of Pasteuria Bioscience, Inc., 12085 Research Drive, Suite 185, Alachua, FL 32615). Product name: Pasteuria nishizawae--Pn1. Active ingredient: Pasteuria nishizawae--Pn1 at 0.01%. Proposed classification/Use: Manufacturing...

Metabonomics and its role in amino acid nutrition research.

PubMed

He, Qinghua; Yin, Yulong; Zhao, Feng; Kong, Xiangfeng; Wu, Guoyao; Ren, Pingping

2011-06-01

Metabonomics combines metabolic profiling and multivariate data analysis to facilitate the high-throughput analysis of metabolites in biological samples. This technique has been developed as a powerful analytical tool and hence has found successful widespread applications in many areas of bioscience. Metabonomics has also become an important part of systems biology. As a sensitive and powerful method, metabonomics can quantitatively measure subtle dynamic perturbations of metabolic pathways in organisms due to changes in pathophysiological, nutritional, and epigenetic states. Therefore, metabonomics holds great promise to enhance our understanding of the complex relationship between amino acids and metabolism to define the roles for dietary amino acids in maintaining health and the development of disease. Such a technique also aids in the studies of functions, metabolic regulation, safety, and individualized requirements of amino acids. Here, we highlight the common workflow of metabonomics and some of the applications to amino acid nutrition research to illustrate the great potential of this exciting new frontier in bioscience.

Course-based undergraduate research experiences in molecular biosciences-patterns, trends, and faculty support.

PubMed

Wang, Jack T H

2017-08-15

Inquiry-driven learning, research internships and course-based undergraduate research experiences all represent mechanisms through which educators can engage undergraduate students in scientific research. In life sciences education, the benefits of undergraduate research have been thoroughly evaluated, but limitations in infrastructure and training can prevent widespread uptake of these practices. It is not clear how faculty members can integrate complex laboratory techniques and equipment into their unique context, while finding the time and resources to implement undergraduate research according to best practice guidelines. This review will go through the trends and patterns in inquiry-based undergraduate life science projects with particular emphasis on molecular biosciences-the research-aligned disciplines of biochemistry, molecular cell biology, microbiology, and genomics and bioinformatics. This will provide instructors with an overview of the model organisms, laboratory techniques and research questions that are adaptable for semester-long projects, and serve as starting guidelines for course-based undergraduate research. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

MALDI mass spectrometry imaging, from its origins up to today: the state of the art.

PubMed

Francese, Simona; Dani, Francesca R; Traldi, Pietro; Mastrobuoni, Guido; Pieraccini, Giuseppe; Moneti, Gloriano

2009-02-01

Mass Spectrometry (MS) has a number of features namely sensitivity, high dynamic range, high resolution, and versatility which make it a very powerful analytical tool for a wide spectrum of applications spanning all the life science fields. Among all the MS techniques, MALDI Imaging mass spectrometry (MALDI MSI) is currently one of the most exciting both for its rapid technological improvements, and for its great potential in high impact bioscience fields. Here, MALDI MSI general principles are described along with technical and instrumental details as well as application examples. Imaging MS instruments and imaging mass spectrometric techniques other than MALDI, are presented along with examples of their use. As well as reporting MSI successes in several bioscience fields, an attempt is made to take stock of what has been achieved so far with this technology and to discuss the analytical and technological advances required for MSI to be applied as a routine technique in clinical diagnostics, clinical monitoring and in drug discovery.

Dynamic nano-imaging of label-free living cells using electron beam excitation-assisted optical microscope

PubMed Central

Fukuta, Masahiro; Kanamori, Satoshi; Furukawa, Taichi; Nawa, Yasunori; Inami, Wataru; Lin, Sheng; Kawata, Yoshimasa; Terakawa, Susumu

2015-01-01

Optical microscopes are effective tools for cellular function analysis because biological cells can be observed non-destructively and non-invasively in the living state in either water or atmosphere condition. Label-free optical imaging technique such as phase-contrast microscopy has been analysed many cellular functions, and it is essential technology for bioscience field. However, the diffraction limit of light makes it is difficult to image nano-structures in a label-free living cell, for example the endoplasmic reticulum, the Golgi body and the localization of proteins. Here we demonstrate the dynamic imaging of a label-free cell with high spatial resolution by using an electron beam excitation-assisted optical (EXA) microscope. We observed the dynamic movement of the nucleus and nano-scale granules in living cells with better than 100 nm spatial resolution and a signal-to-noise ratio (SNR) around 10. Our results contribute to the development of cellular function analysis and open up new bioscience applications. PMID:26525841

Dynamic nano-imaging of label-free living cells using electron beam excitation-assisted optical microscope.

PubMed

Fukuta, Masahiro; Kanamori, Satoshi; Furukawa, Taichi; Nawa, Yasunori; Inami, Wataru; Lin, Sheng; Kawata, Yoshimasa; Terakawa, Susumu

2015-11-03

Optical microscopes are effective tools for cellular function analysis because biological cells can be observed non-destructively and non-invasively in the living state in either water or atmosphere condition. Label-free optical imaging technique such as phase-contrast microscopy has been analysed many cellular functions, and it is essential technology for bioscience field. However, the diffraction limit of light makes it is difficult to image nano-structures in a label-free living cell, for example the endoplasmic reticulum, the Golgi body and the localization of proteins. Here we demonstrate the dynamic imaging of a label-free cell with high spatial resolution by using an electron beam excitation-assisted optical (EXA) microscope. We observed the dynamic movement of the nucleus and nano-scale granules in living cells with better than 100 nm spatial resolution and a signal-to-noise ratio (SNR) around 10. Our results contribute to the development of cellular function analysis and open up new bioscience applications.

Dynamic nano-imaging of label-free living cells using electron beam excitation-assisted optical microscope

NASA Astrophysics Data System (ADS)

Fukuta, Masahiro; Kanamori, Satoshi; Furukawa, Taichi; Nawa, Yasunori; Inami, Wataru; Lin, Sheng; Kawata, Yoshimasa; Terakawa, Susumu

2015-11-01

Optical microscopes are effective tools for cellular function analysis because biological cells can be observed non-destructively and non-invasively in the living state in either water or atmosphere condition. Label-free optical imaging technique such as phase-contrast microscopy has been analysed many cellular functions, and it is essential technology for bioscience field. However, the diffraction limit of light makes it is difficult to image nano-structures in a label-free living cell, for example the endoplasmic reticulum, the Golgi body and the localization of proteins. Here we demonstrate the dynamic imaging of a label-free cell with high spatial resolution by using an electron beam excitation-assisted optical (EXA) microscope. We observed the dynamic movement of the nucleus and nano-scale granules in living cells with better than 100 nm spatial resolution and a signal-to-noise ratio (SNR) around 10. Our results contribute to the development of cellular function analysis and open up new bioscience applications.

Closing the Social Class Achievement Gap for First-Generation Students in Undergraduate Biology

PubMed Central

Harackiewicz, Judith M.; Canning, Elizabeth A.; Tibbetts, Yoi; Giffen, Cynthia J.; Blair, Seth S.; Rouse, Douglas I.; Hyde, Janet S.

2014-01-01

Many students start college intending to pursue a career in the biosciences, but too many abandon this goal because they struggle in introductory biology. Interventions have been developed to close achievement gaps for underrepresented minority students and women, but no prior research has attempted to close the gap for first-generation students, a population that accounts for nearly a fifth of college students. We report a values affirmation intervention conducted with 798 U.S. students (154 first-generation) in an introductory biology course for majors. For first-generation students, values affirmation significantly improved final course grades and retention in the second course in the biology sequence, as well as overall GPA for the semester. This brief intervention narrowed the achievement gap between first-generation and continuing generation students for course grades by 50% and increased retention in a critical gateway course by 20%. Our results suggest that educators can expand the pipeline for first-generation students to continue studying in the biosciences with psychological interventions. PMID:25049437

Assessment of Collaboration and Interoperability in an Information Management System to Support Bioscience Research

PubMed Central

Myneni, Sahiti; Patel, Vimla L.

2009-01-01

Biomedical researchers often have to work on massive, detailed, and heterogeneous datasets that raise new challenges of information management. This study reports an investigation into the nature of the problems faced by the researchers in two bioscience test laboratories when dealing with their data management applications. Data were collected using ethnographic observations, questionnaires, and semi-structured interviews. The major problems identified in working with these systems were related to data organization, publications, and collaboration. The interoperability standards were analyzed using a C4I framework at the level of connection, communication, consolidation, and collaboration. Such an analysis was found to be useful in judging the capabilities of data management systems at different levels of technological competency. While collaboration and system interoperability are the “must have” attributes of these biomedical scientific laboratory information management applications, usability and human interoperability are the other design concerns that must also be addressed for easy use and implementation. PMID:20351900

Minimizing the formation of coke and methane on Co nanoparticles in steam reforming of biomass-derived oxygenates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sun, Junming; Mei, Donghai; Karim, Ayman M.

2013-06-01

Fundamental understanding and control of chemical transformations are essential to the development of technically feasible and economically viable catalytic processes for efficient conversion of biomass to fuels and chemicals. Using an integrated experimental and theoretical approach, we report high hydrogen selectivity and catalyst durability of acetone steam reforming (ASR) on inert carbon supported Co nanoparticles. The observed catalytic performance is further elucidated on the basis of comprehensive first-principles calculations. Instead of being considered as an undesired intermediate prone for catalyst deactivation during bioethanol steam reforming (ESR), acetone is suggested as a key and desired intermediate in proposed two-stage ESR processmore » that leads to high hydrogen selectivity and low methane formation on Co-based catalysts. The significance of the present work also sheds a light on controlling the chemical transformations of key intermediates in biomass conversion such as ketones. We gratefully acknowledge the financial support from U. S. Department of Energy (DOE), Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences, and Biosciences, and the Laboratory directed research and development (LDRD) project of Pacific Northwest National Laboratory (PNNL). Computing time was granted by the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL). The EMSL is a U.S. DOE national scientific user facility located at PNNL, and sponsored by the U.S. DOE’s Office of Biological and Environmental Research.« less

Air Pollution Publications, A Selected Bibliography With Abstracts, 1966-1968.

ERIC Educational Resources Information Center

National Air Pollution Control Administration (DHEW), Washington, DC.

Contained are over 1000 entries with abstracts spanning the literature from 1966 to 1968. The references are grouped into broad subject categories: emission sources; atmospheric interactions; measurement; control methods; biosciences and medicine; plants; materials deterioration; air quality; legal and administrative aspects; social aspects; basic…

IBBR and Frederick National Laboratory Collaborate to Study Vaccine-Boosting Compounds | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory and the University of Maryland’s Institute for Bioscience and Biotechnology Research (IBBR) will work under a formal collaboration to evaluate the effectiveness of new compounds that might be used to enhance the im

Competitiveness of Second Generation Biofuel Feedstocks: Role of Technology and Policy (2010 JGI User Meeting)

ScienceCinema

Khanna, Madhu

2018-02-19

Madhu Khanna from the University of Illinois at Urbana-Champaign and the Energy Biosciences Institute on Competitiveness of Second Generation Biofuel Feedstocks: Role of Technology and Policy on March 25, 2010 at the 5th Annual DOE JGI User Meeting.

The returning tide:

PubMed Central

Wells, William A.

2007-01-01

When China turned its back on the Cultural Revolution, it aimed to build a thriving capitalist sector. It got one. Now, it wants a world-class research enterprise. How far has it progressed in the biosciences, how did it get there, and how far does it have to go? PMID:17296791

Lessons from Interspecies Mammalian Chimeras.

PubMed

Suchy, Fabian; Nakauchi, Hiromitsu

2017-10-06

As chimeras transform from beasts of Greek mythology into tools of contemporary bioscience, secrets of developmental biology and evolutionary divergence are being revealed. Recent advances in stem cell biology and interspecies chimerism have generated new models with extensive basic and translational applications, including generation of transplantable, patient-specific organs.

Machine Learning Approaches to Increasing Value of Spaceflight Omics Databases

NASA Technical Reports Server (NTRS)

Gentry, Diana

2017-01-01

The number of spaceflight bioscience mission opportunities is too small to allow all relevant biological and environmental parameters to be experimentally identified. Simulated spaceflight experiments in ground-based facilities (GBFs), such as clinostats, are each suitable only for particular investigations -- a rotating-wall vessel may be 'simulated microgravity' for cell differentiation (hours), but not DNA repair (seconds) -- and introduce confounding stimuli, such as motor vibration and fluid shear effects. This uncertainty over which biological mechanisms respond to a given form of simulated space radiation or gravity, as well as its side effects, limits our ability to baseline spaceflight data and validate mission science. Machine learning techniques autonomously identify relevant and interdependent factors in a data set given the set of desired metrics to be evaluated: to automatically identify related studies, compare data from related studies, or determine linkages between types of data in the same study. System-of-systems (SoS) machine learning models have the ability to deal with both sparse and heterogeneous data, such as that provided by the small and diverse number of space biosciences flight missions; however, they require appropriate user-defined metrics for any given data set. Although machine learning in bioinformatics is rapidly expanding, the need to combine spaceflight/GBF mission parameters with omics data is unique. This work characterizes the basic requirements for implementing the SoS approach through the System Map (SM) technique, a composite of a dynamic Bayesian network and Gaussian mixture model, in real-world repositories such as the GeneLab Data System and Life Sciences Data Archive. The three primary steps are metadata management for experimental description using open-source ontologies, defining similarity and consistency metrics, and generating testing and validation data sets. Such approaches to spaceflight and GBF omics data may soon enable unique insight into which measured phenomena correlate to biological mechanisms that are truly affected by spaceflight conditions; which are most likely to be confounded by other variables; and which are insufficiently characterized, significantly increasing existing and future science return from ISS and spaceflight missions.

Micrometeorological flux measurements at a coastal site

NASA Astrophysics Data System (ADS)

Song, Guozheng; Meixner, Franz X.; Bruse, Michael; Mamtimin, Buhalqem

2014-05-01

The eddy covariance (EC) technique is the only direct measurement of the momentum, heat, and trace gas (e.g. water vapor, CO2 and ozone) fluxes. The measurements are expected to be most accurate over flat terrain where there is an extended homogenous surface upwind from the tower, and when the environmental conditions are steady. Additionally, the one dimensional approach assumes that vertical turbulent exchange is the dominant flux, whereas advective influences should be negligible. The application of EC method under non-ideal conditions, for example in complex terrain, has yet to be fully explored. To explore the possibilities and limitations of EC technique under non-ideal conditions, an EC system was set up at Selles beach, Crete, Greece (35.33°N, 25.71°E) in the beginning of July 2012. The dominant wind direction was west, parallel to the coast. The EC system consisted of a sonic anemometer (CSAT3 Campbell Scientific), an infrared open-path CO2/H2O gas analyzer (LI-7500, Li-COR Biosciences) and a fast chemiluminescence ozone analyzer (enviscope GmbH). All the signals of these fast response instruments were sampled at 10 Hz and the measurement height was 3 m. Besides, another gradient system was setup. Air temperature, relative humidity (HYGROMER MP 103 A), and wind speed (WMT700 Vaisala) were measured every 10 seconds at 3 heights (0.7, 1.45, 3 m). Air intakes were set up at 0.7m and 3m. A pump drew the air through a flow system and a telflon valve alternately switched between the two heights every 30 seconds. H2O, CO2 (LI-840A, Li-COR Biosciences) and ozone mixing ratio s (model 205, 2BTechnologies) were measured every 10 seconds. Momentum, heat, CO2 and ozone fluxes were evaluated by both EC and gradient technique. For the calculation of turbulent fluxes, TK3 algorithm (Department of Micrometeorology, University Bayreuth, Germany) was applied. We will present the measured fluxes of the two systems and assess the data quality under such non-ideal condition.

Breakdown Breakthrough: NREL Finds Easier Ways to Deconstruct Biomass |

Science.gov Websites

soften biomass. Photo by Dennis Schroeder, NREL If there's an easier, more efficient method, science will Dennis Schroeder, NREL The process normally used to deconstruct biomass, called simultaneous in NREL's Biosciences Center. Photo by Dennis Schroeder, NREL New Technology Could Provide Boost to

Comparison of Soluble and Immobilised Enzymes

ERIC Educational Resources Information Center

Wiseman, Alan

2003-01-01

This short article was written in response to a proposed practical featured in the Spring 2002 issue of the "Journal of Biological Education." Beaumont, Cotterill and Williams described a system representing a useful way by which the deleterious effects of free radical attack on enzymes can be demonstrated to undergraduate bioscience students,…

The Promise and Challenge of Producing Biofuel Feedstocks: An Ecological Perspective (2010 JGI User Meeting)

ScienceCinema

DeLucia, Evan

2018-02-13

Evan DeLucia of the University of Illinois at Urbana-Champaign and the Energy Biosciences Institute talks about The Promise and Challenge of Producing Biofuel Feedstocks: An Ecological Perspective on March 25, 2010 at the 5th Annual DOE JGI User Meeting.

Injury and Disability: Identification and Reduction

DTIC Science & Technology

2009-09-01

Biomechanics Branch September 2009 Final Report for October 2005 to August 2009 DESTRUCTION NOTICE – Destroy by any method that will prevent...Division Biomechanics Branch Wright-Patterson AFB OH 45433 Approved for public release, distribution unlimited. NOTICE AND SIGNATURE PAGE...Chief Biomechanics Branch Biosciences and Protection Division Human Effectiveness Directorate 711 th

Focus on Methodology: Salivary Bioscience and Research on Adolescence: An Integrated Perspective

ERIC Educational Resources Information Center

Granger, Douglas A.; Fortunato, Christine K.; Beltzer, Emilie K.; Virag, Marta; Bright, Melissa A.; Out, Dorothee

2012-01-01

The characterization of the salivary proteome and advances in biotechnology create an opportunity for developmental scientists to measure multi-level components of biological systems in oral fluids and identify relationships with developmental processes and behavioral and social forces. The implications for developmental science are profound…

Apprenticeship in Science Research: Whom Does It Serve?

ERIC Educational Resources Information Center

Davies, Paul

2016-01-01

This article advances the thinking of Thompson, Conaway and Dolan's "Undergraduate students' development of social, cultural, and human capital in a network research experience". Set against a background of change in the biosciences, and participation, it firstly explores ideas of what it means to be a scientist, then challenges the…

Bioethics Center: An Idea Whose Time Had Come

ERIC Educational Resources Information Center

Chemical and Engineering News, 1974

1974-01-01

The functioning of the Kennedy Institute, which aims at dealing with ethical and social questions raised by advances in biosciences and medicine, is described. Three major projects now underway are briefly discussed: a core reference library in bioethics, an Encyclopedia of Bioethics, and a bioethics information retrieval system. (DT)

Demand for Interdisciplinary Laboratories for Physiology Research by Undergraduate Students in Biosciences and Biomedical Engineering

ERIC Educational Resources Information Center

Clase, Kari L.; Hein, Patrick W.; Pelaez, Nancy J.

2008-01-01

Physiology as a discipline is uniquely positioned to engage undergraduate students in interdisciplinary research in response to the 2006-2011 National Science Foundation Strategic Plan call for innovative transformational research, which emphasizes multidisciplinary projects. To prepare undergraduates for careers that cross disciplinary…

Changes in Academic Entrepreneurship among Japanese University Bioscientists, 1980-2012

ERIC Educational Resources Information Center

Kameo, Nahoko

2014-01-01

The dissertation examines how Japanese university scientists in the biosciences responded to legal and institutional changes in academic entrepreneurship. Beginning in the 1990s, the Japanese government initiated a series of policy initiatives that attempted to imitate the U.S. academic environment's approach to promoting entrepreneurship. Using…

The Role of the Virtual Microscope in Distance Learning

ERIC Educational Resources Information Center

Whalley, Peter; Kelley, Simon; Tindle, Andrew

2011-01-01

Screen-based microscopes allow for a shared visualisation and task-directed conversations that offer significant pedagogic advantages for the science disciplines involving observation of natural samples such as the geosciences and biosciences, and particularly for distance education in these disciplines. The role and development of a virtual…

Embedding Enterprise in Biosciences: Added Value for Employability

ERIC Educational Resources Information Center

Watts, Carys; Wray, Katie; Kennedy, Ciara; Freeman, Paul; Trainer, Gareth

2010-01-01

Enterprise education at Newcastle University, UK, is embedded in the fabric of the curriculum via the Newcastle University Graduate Skills Framework. An example of this is the "Business for the Bioscientist" module. The authors discuss this module with regard to good practice, enterprise development and the wider arena of graduate…

Estimating the Size of Onion Epidermal Cells from Diffraction Patterns

ERIC Educational Resources Information Center

Groff, Jeffrey R.

2012-01-01

Bioscience and premedical profession students are a major demographic served by introductory physics courses at many colleges and universities. Exposing these students to biological applications of physical principles will help them to appreciate physics as a useful tool for their future professions. Here I describe an experiment suitable for…

Enrichment and Strengthening of Indian Biotechnology Industry along with Academic Interface

ERIC Educational Resources Information Center

Singh, Shalini

2014-01-01

For many years, humankind has been incorporating biosciences in different places--from agriculture to food and medicine. Today, the nomenclature of biology has been recoined as Biotechnology, a technological science with a perfect blend of sophisticated techniques, manuals and application of fast delivery equipment and vehicles. It encompasses…

History of cotton fiber bioscience research at USDA-ARS Southern Regional Research Center

USDA-ARS?s Scientific Manuscript database

Improving fiber quality has been an important breeding goal for cotton breeders. Better understanding of fiber development helps cotton scientists to devise a strategy for crop improvement either through marker-assisted selection or via manipulation of fiber genes. USDA-ARS Southern Regional Researc...

Cloning: Past, Present, and the Exciting Future. Breakthroughs in Bioscience.

ERIC Educational Resources Information Center

Di Berardino, Marie A.

This document explores the history of cloning by focusing on Dolly the Sheep, one of the first large animal clonings. The disadvantages and advantages of transgenic clones are discussed as well as the future implications of cloning from the perspective of human health. (Contains 10 resources.) (YDS)

78 FR 32248 - Notice of Receipt of a Request to Voluntarily Cancel Certain Pesticide Registrations

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-29

...). ACTION: Notice. SUMMARY: In accordance with the Federal Insecticide, Fungicide, and Rodenticide Act... for the allethrins end-use products will be effective December 31, 2016, as described in Unit II. If... 2020. The technical registrants (Sumitomo Chemical Company Limited and Valent BioSciences Corporation...

Enhancing the Student Experience of Laboratory Practicals through Digital Video Guides

ERIC Educational Resources Information Center

Croker, Karen; Andersson, Holger; Lush, David; Prince, Rob; Gomez, Stephen

2010-01-01

Laboratory-based learning allows students to experience bioscience principles first hand. In our experience, practical content and equipment may have changed over time, but teaching methods largely remain the same, typically involving; whole class introduction with a demonstration, students emulating the demonstration in small groups, gathering…

Online Preparation Resources Help First Year Students to Benefit from Practical Classes

ERIC Educational Resources Information Center

Whittle, Sue R.; Bickerdike, Sue R.

2015-01-01

Practical skills are important for the employability of biosciences graduates; however, first year science undergraduates often struggle to adapt to university practical classes, affecting skills development and decreasing their enthusiasm for laboratory work. This study describes the effects of introducing online multimedia practical support…

A Biosafety Level 2 Virology Lab for Biotechnology Undergraduates

ERIC Educational Resources Information Center

Matza-Porges, Sigal; Nathan, Dafna

2017-01-01

Medical, industrial, and basic research relies heavily on the use of viruses and vectors. Therefore, it is important that bioscience undergraduates learn the practicalities of handling viruses. Teaching practical virology in a student laboratory setup presents safety challenges, however. The aim of this article is to describe the design and…

77 FR 14023 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-08

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... and Alcoholism Special Emphasis Panel; NIAAA Member Conflict application reviews--Biosciences. Date...

Stimulate Students' Interest by Genetics Exordium Teaching

ERIC Educational Resources Information Center

Li, Yan

2009-01-01

Genetics is the important specialized course of bioscience and whether exordium is taught wonderfully or not plays the important and pivotal role. Well teaching exordium class may stimulate students, deep interest and intense desire for knowledge in this class. This text, according to teaching experience and taste, puts forward several teaching…

Additional annotation of the pig transcriptome using integrated Iso-seq and Illumina RNA-seq analysis

USDA-ARS?s Scientific Manuscript database

Alternative splicing is a well-known phenomenon that dramatically increases eukaryotic transcriptome diversity. The extent of mRNA isoform diversity among porcine tissues was assessed using Pacific Biosciences single-molecule long-read isoform sequencing (Iso-Seq) and Illumina short read sequencing ...

Changing the Mechanism for CO 2 Hydrogenation Using Solvent-Dependent Thermodynamics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burgess, Samantha A.; Appel, Aaron M.; Linehan, John C.

A critical scientific challenge for utilization of CO2 is the development of catalyst systems that do not depend upon expensive or environmentally unfriendly reagents, such as precious metals, strong organic bases, and organic solvents. We have used thermodynamic insights to predict and demonstrate that the HCoI(dmpe)2 catalyst system, previously described for use in organic solvents, can hydrogenate CO2 to formate in water with bicarbonate as the only added reagent. Replacing tetrahydrofuran as the solvent with water changes the mechanism for catalysis by altering the thermodynamics for hydride transfer to CO2 from a key dihydride intermediate. The need for a strongmore » organic base was eliminated by performing catalysis in water due to the change in mechanism. These studies demonstrate that the solvent plays a pivotal role in determining the reaction thermodynamics and thereby catalytic mechanism and activity. The research was supported by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences, and Biosciences. Pacific Northwest National Laboratory is operated by Battelle for the U.S. Department of Energy.« less

KSC-07pd2601

NASA Image and Video Library

2007-09-28

KENNEDY SPACE CENTER, FLA. STS-122 Mission Specialist Hans Schlegel looks closely at the hatch on the Columbus Research Laboratory in the Space Station Processing Facility. Schegel represents the European Space Agency. The crew is at Kennedy to take part in a crew equipment interface test, which helps familiarize them with equipment and payloads for the mission. Among the activities standard to a CEIT are harness training, inspection of the thermal protection system and camera operation for planned extravehicular activities, or EVAs. The Columbus Lab is Europe’s largest contribution to the construction of the International Space Station. It will support scientific and technological research in a microgravity environment. Columbus, a program of ESA, is a multifunctional, pressurized laboratory that will be permanently attached to Node 2 of the space station to carry out experiments in materials science, fluid physics and biosciences, as well as to perform a number of technological applications. STS-122 is targeted for launch in December. Photo credit: NASA/Jim Grossmann

Educating Physicists for the 21st Century Industrial Arena

NASA Astrophysics Data System (ADS)

Levine, Alaina G.

2001-03-01

At the University of Arizona, a new Professional Master's Degree in Applied and Industrial Physics has been initiated to meet the demands of a new industrial era. A 1995 report by the National Academy of Sciences, et al, concluded, "A world of work that has become more interdisciplinary, collaborative, and global requires that we produce young people who are adaptable and flexible, as well as technically proficient." To better prepare students for this new "world of work", a new degree was launched in 2000 sponsored by the Sloan Foundation as part of a national initiative. The Professional Master's Degree in Applied and Industrial Physics educates students to 1) work in interdisciplinary teams on complex problems involving rapidly changing science and technology, 2) gain proficiency in computational techniques, 3) effectively communicate their scientific mission at all levels, and 4) understand business and legal issues associated with their scientific projects. I will discuss these goals, the roles of our industrial partners, and Arizona's parallel programs in Applied Biosciences and Mathematical Sciences.

Dried Blood Spot Proteomics: Surface Extraction of Endogenous Proteins Coupled with Automated Sample Preparation and Mass Spectrometry Analysis

NASA Astrophysics Data System (ADS)

Martin, Nicholas J.; Bunch, Josephine; Cooper, Helen J.

2013-08-01

Dried blood spots offer many advantages as a sample format including ease and safety of transport and handling. To date, the majority of mass spectrometry analyses of dried blood spots have focused on small molecules or hemoglobin. However, dried blood spots are a potentially rich source of protein biomarkers, an area that has been overlooked. To address this issue, we have applied an untargeted bottom-up proteomics approach to the analysis of dried blood spots. We present an automated and integrated method for extraction of endogenous proteins from the surface of dried blood spots and sample preparation via trypsin digestion by use of the Advion Biosciences Triversa Nanomate robotic platform. Liquid chromatography tandem mass spectrometry of the resulting digests enabled identification of 120 proteins from a single dried blood spot. The proteins identified cross a concentration range of four orders of magnitude. The method is evaluated and the results discussed in terms of the proteins identified and their potential use as biomarkers in screening programs.

Computer-aided design of biological circuits using TinkerCell.

PubMed

Chandran, Deepak; Bergmann, Frank T; Sauro, Herbert M

2010-01-01

Synthetic biology is an engineering discipline that builds on modeling practices from systems biology and wet-lab techniques from genetic engineering. As synthetic biology advances, efficient procedures will be developed that will allow a synthetic biologist to design, analyze, and build biological networks. In this idealized pipeline, computer-aided design (CAD) is a necessary component. The role of a CAD application would be to allow efficient transition from a general design to a final product. TinkerCell is a design tool for serving this purpose in synthetic biology. In TinkerCell, users build biological networks using biological parts and modules. The network can be analyzed using one of several functions provided by TinkerCell or custom programs from third-party sources. Since best practices for modeling and constructing synthetic biology networks have not yet been established, TinkerCell is designed as a flexible and extensible application that can adjust itself to changes in the field. © 2010 Landes Bioscience

Investigation of injury/illness data at a nuclear facility. Part II

DOE PAGES

Cournoyer, Michael E.; Garcia, Vincent E.; Sandoval, Arnold N.; ...

2015-07-01

At Los Alamos National Laboratory (LANL), there are several nuclear facilities, accelerator facilities, radiological facilities, explosives sites, moderate- and high-hazard non-nuclear facilities, biosciences laboratory, etc. The Plutonium Science and Manufacturing Directorate (ADPSM) provides special nuclear material research, process development, technology demonstration, and manufacturing capabilities. ADPSM manages the LANL Plutonium Facility. Within the Radiological Control Area at TA-55 (PF-4), chemical and metallurgical operations with plutonium and other hazardous materials are performed. LANL Health and Safety Programs investigate injury and illness data. In this study, statistically significant trends have been identified and compared for LANL, ADPSM, and PF-4 injury/illness cases. A previouslymore » described output metric is used to measures LANL management progress towards meeting its operational safety objectives and goals. Timelines are used to determine trends in Injury/Illness types. Pareto Charts are used to prioritize causal factors. The data generated from analysis of Injury/Illness data have helped identify and reduce the number of corresponding causal factors.« less

Simulating Phase Variation: A Practical Approach to Teaching Mutation and Diversity

ERIC Educational Resources Information Center

Wanford, Joe; Aidley, Jack; Bayliss, Chris; Ketley, Julian; Goodwin, Mark

2018-01-01

Mutation, diversity, natural selection and the biology of human pathogens (including antibiotic resistance) are key features of the biosciences curriculum at A Level and undergraduate study. Few resources exist to allow students to engage with these topics in an interactive manner. This paper describes an interactive, online simulation of mutation…

Bioculture System Expanding ISS Capabilities for Space Biosciences Research and Commercial Applications

NASA Technical Reports Server (NTRS)

Sato, Kevin Y.

2013-01-01

Oral presentation at the ASGSR 2013 Annual Meeting. The presentation describes the NASA Bioculture System hardware design, capabilities, enabling science research capabilities, and flight concept of operations. The presentation is part of the Enabling Technologies special session and will be presented to perspective users in both academics and commercial communities.

The Utility of Writing Assignments in Undergraduate Bioscience

ERIC Educational Resources Information Center

Libarkin, Julie; Ording, Gabriel

2012-01-01

We tested the hypothesis that engagement in a few, brief writing assignments in a nonmajors science course can improve student ability to convey critical thought about science. A sample of three papers written by students (n = 30) was coded for presence and accuracy of elements related to scientific writing. Scores for different aspects of…

Curating Blood: How Students' and Researchers' Drawings Bring Potential Phenomena to Light

ERIC Educational Resources Information Center

Hay, D. B.; Pitchford, S.

2016-01-01

This paper explores students and researchers drawings of white blood cell recruitment. The data combines interviews with exhibit of review-type academic images and analyses of student model-drawings. The analysis focuses on the material aspects of bioscientific data-making and we use the literature of concrete bioscience modelling to differentiate…

Quantitative Skills as a Graduate Learning Outcome: Exploring Students' Evaluative Expertise

ERIC Educational Resources Information Center

Matthews, Kelly E.; Adams, Peter; Goos, Merrilyn

2017-01-01

In the biosciences, quantitative skills are an essential graduate learning outcome. Efforts to evidence student attainment at the whole of degree programme level are rare and making sense of such data is complex. We draw on assessment theories from Sadler (evaluative expertise) and Boud (sustainable assessment) to interpret final-year bioscience…

Box 11: Tissue Engineering and Bioscience Methods Using Proton Beam Writing

NASA Astrophysics Data System (ADS)

van Kan, J. A.

Tissue engineering is a rapidly developing and highly interdisciplinary field that applies the principles of cell biology, engineering, and materials science to the culture of biological tissue. The artificially grown tissue then can be implanted directly into the body, or it can form part of a device that replaces organ functionality.

Communicating Biotech Advances: Fiction versus Reality.

PubMed

Małyska, Aleksandra; Bolla, Robert; Twardowski, Tomasz

2018-02-01

Bioscience novels use selected technologies of genetic engineering and synthetic biology to create entertaining stories. These novels are usually based on scientific knowledge, but they may arouse public concerns about technology and drive public reluctance to accept innovative technologies. The scientific community must adopt more efficient communication and transparency. Copyright © 2017 Elsevier Ltd. All rights reserved.

Bioinformatics: Current Practice and Future Challenges for Life Science Education

ERIC Educational Resources Information Center

Hack, Catherine; Kendall, Gary

2005-01-01

It is widely predicted that the application of high-throughput technologies to the quantification and identification of biological molecules will cause a paradigm shift in the life sciences. However, if the biosciences are to evolve from a predominantly descriptive discipline to an information science, practitioners will require enhanced skills in…

Evaluation of production method and formulation for optimizing in-vitro produced Gypchek

Treesearch

R. E. Webb; G. B. White; K. W. Thorpe; J. M. Slavicek; J. D. Podgwaite; R. W. Fuester; P. B. Taylor; R. A. Peiffer; M. A. Valenti

2003-01-01

Gypchek (USDA Forest Service, Washington, DC), a product with the Lymantria dispar multi-enveloped nucleopolyhedrovirus (LdMNPV) as the active ingredient, is a general use biopesticide for use against the gypsy moth. Successful field trials with Gypchek incorporated with the commercially-produced Carrier 038 (Valent BioSciences Corp., Libertyville,...

The Endangered Species Act and Sound Science

DTIC Science & Technology

2006-10-05

A. Mehrhoff, Mary J. Parkin, Diane R. Elam, and Linus Y. Chen, “Endangered Species Recovery and the SCB Study: A U.S. Fish and Wildlife Service...2003. 99 Ellen Paul , “Science: The Newest Political Football in the Endangered Species Game,” BioScience, v. 52, no. 9 (September 2002): 792. A

"Here's One We Prepared Earlier": Involving Former Students in Careers Advice

ERIC Educational Resources Information Center

Willmott, Chris

2011-01-01

Graduate employability is an important concern for contemporary universities. Alongside the development of employability skills, it is also crucial that students of bioscience, a "non-vocational" subject, have awareness of the breadth of potential careers that can follow from their initial degree. Over the past five years we have developed the…

Teaching Bioethics via the Production of Student-Generated Videos

ERIC Educational Resources Information Center

Willmott, Christopher J. R.

2015-01-01

There is growing recognition that science is not conducted in a vacuum and that advances in the biosciences have ethical and social implications for the wider community. An exercise is described in which undergraduate students work in teams to produce short videos about the science and ethical dimensions of current developments in biomedicine.…

Lessons Learned from Undergraduate Students in Designing a Science-Based Course in Bioethics

ERIC Educational Resources Information Center

Loike, John D.; Rush, Brittany S.; Schweber, Adam; Fischbach, Ruth L.

2013-01-01

Columbia University offers two innovative undergraduate science-based bioethics courses for student majoring in biosciences and pre-health studies. The goals of these courses are to introduce future scientists and healthcare professionals to the ethical questions they will confront in their professional lives, thus enabling them to strategically…

Sequencing Technologies Panel at SFAF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Turner, Steve; Fiske, Haley; Knight, Jim

2010-06-02

From left to right: Steve Turner of Pacific Biosciences, Haley Fiske of Illumina, Jim Knight of Roche, Michael Rhodes of Life Technologies and Peter Vander Horn of Life Technologies' Single Molecule Sequencing group discuss new sequencing technologies and applications on June 2, 2010 at the "Sequencing, Finishing, Analysis in the Future" meeting in Santa Fe, NM

Bioscience and the Sociology of Education: The Case for Biosocial Education

ERIC Educational Resources Information Center

Youdell, Deborah

2017-01-01

This article makes a case for biosocial education as a field of research and as a potential framework for education practice. The article engages with sociology of education's contemporary interests in embodiment and affect, the possibilities offered by concept studies, and uses of assemblage and complexity theory for thinking about educational…

Written Feedback for Students: Too Much, Too Detailed or Too Incomprehensible to Be Effective?

ERIC Educational Resources Information Center

Glover, Chris; Brown, Evelyn

2006-01-01

A three year research study entitled "Improving the effectiveness of Formative Assessment in Science Teaching", involving Biosciences and Physical Sciences staff and students at two UK Universities, has been examining the potential for improving student learning by making changes to the way formative assessment and feedback are…

Complete Genome Sequence of Kluyveromyces lactis Strain GG799, a Common Yeast Host for Heterologous Protein Expression

PubMed Central

Chuzel, Léa; Ganatra, Mehul B.; Schermerhorn, Kelly M.; Gardner, Andrew F.; Anton, Brian P.

2017-01-01

ABSTRACT We report the genome sequence of the dairy yeast Kluyveromyces lactis strain GG799 obtained using the Pacific Biosciences RS II platform. K. lactis strain GG799 is a common host for the expression of proteins at both laboratory and industrial scales. PMID:28751387

Sediment Flux to the Coastal Zone: Predictions for the Navy

DTIC Science & Technology

2001-09-30

synthesis paper on anthropogenic disturbance of the water cycle (Vörösmarty and Sahagian 2000) which was found to be significant in terms of distorting...Practice, pp. 43-80. Island Press, Washington DC. Vörösmarty, C.J. and Sahagian, D., 2000. Anthropogenic disturbance of the terrestrial water cycle . BioScience

The Notion of Scientific Knowledge in Biology

ERIC Educational Resources Information Center

Morante, Silvia; Rossi, Giancarlo

2016-01-01

The purpose of this work is to reconsider and critically discuss the conceptual foundations of modern biology and bio-sciences in general, and provide an epistemological guideline to help framing the teaching of these disciplines and enhancing the quality of their presentation in High School, Master and Ph.D. courses. After discussing the…

Entrepreneurship for Bioscience Researchers: A Case Study of an Entrepreneurship Programme

ERIC Educational Resources Information Center

Heinonen, Jarna; Poikkijoki, Sari-Anne; Vento-Vierikko, Irma

2007-01-01

Entrepreneurship is reaching new areas in which the concept of business is more or less unfamiliar and remote. This study focuses on a specific entrepreneurship education programme in the fields of chemistry, physics, information technology and bioinformatics, life sciences and medicine development. The aim is to gain a deeper understanding of the…

Mathematical Struggles and Ensuring Success: Post-Compulsory Mathematics as Preparation for Undergraduate Bioscience

ERIC Educational Resources Information Center

Bowyer, Jessica; Darlington, Ellie

2018-01-01

This article reports on data from a large-scale study investigating students' mathematical transitions to higher education. Three hundred and seventy-one undergraduate bioscientists were surveyed in order to investigate their perceptions and experiences of studying post-compulsory mathematics, as preparation for the mathematics elements of their…

Interaction of resident sperm with sperm-storage tubule (SST) epithelial cell microvilli in the turkey breeder hen

USDA-ARS?s Scientific Manuscript database

Interaction of resident sperm with sperm-storage tubule (SST) epithelial cell microvilli in the turkey breeder hen M.R. Bakst*1 and C. Murphy2, 1Animal Biosciences and Biotechnology Laboratory, 2Electron & Confocal Microscopy Unit, Beltsville Area, ARS, USDA, Beltsville MD Sustained fertilization o...

Aeolian Nutrient Fluxes Following Wildfire in Sagebrush Steppe: Implications for Soil Carbon Storage

DTIC Science & Technology

2011-12-14

World atlas of desertification , Arnold, London, 1997. Miller, R. F. and Heyerdahl, E. K.: Fine-scale variation of historical fire regimes in...Fredrickson, E. L.: Do changes in connectivity explain desertification ?, Bioscience, 59, 237–244, 2009. Rau, B. M., Chambers, J. C., Blank, R. R., and

21 CFR 212.5 - To what drugs do the regulations in this part apply?

Code of Federal Regulations, 2010 CFR

2010-04-01

... requirements in parts 210 and 211 of this chapter. (b) Investigational and research PET drugs. For... part 312 of this chapter, and PET drugs produced with the approval of a Radioactive Drug Research... Drug Administration Biosciences Library, 10903 New Hampshire Ave., Silver Spring, MD, 20993-0002, 301...

The Learning Gains and Student Perceptions of a Second Life Virtual Lab

ERIC Educational Resources Information Center

Cobb, Stephanie; Heaney, Rose; Corcoran, Olivia; Henderson-Begg, Stephanie

2009-01-01

This study examines students' reactions to the virtual biosciences laboratory developed in Second Life[R] (SL) at the University of East London. Final year undergraduates and masters students studying biotechnology took part in a trial of a virtual Polymerase Chain Reaction (PCR) experiment in Second Life and evaluated their experience by…

Study of denture-induced fibrous hyperplasia cases diagnosed from 1979 to 2001.

PubMed

Macedo Firoozmand, Leily; Dias Almeida, Janete; Guimarães Cabral, Luiz Antonio

2005-01-01

The purpose of this research was to study the cases of inflammatory fibrous hyperplasia (IFH) at the Clinic of Semiology, Department of Bioscience and Oral Diagnosis, São Jose dos Campos Dental School, State University of São Paulo, Brazil. A total of 141 clinical file cards indicating a final diagnosis of IFH, from the archives of the Department of Bioscience and Oral Diagnosis and dated from 1979 to 2001, were included in the study. Of these files, 50 indicated a diagnosis of denture-induced fibrous hyperplasia. Sex, age, race, duration, and clinical features that confirm their classification in the non-neoplastic proliferating process were analyzed statistically. Of the 50 analyzed cases of denture-induced lesion, 22% occurred in men and 78% in women. Patients in the age group of 41 to 50 years presented the highest frequency of the lesion. Inflammatory fibrous hyperplasia occurs more frequently in women (71.63%), and denture-induced lesions appear mainly in patients over 40 years of age (70% of cases). Patients with denture-induced hyperplasia reported pain associated with the lesion (70%).

Novel GM animal technologies and their governance.

PubMed

Bruce, Ann; Castle, David; Gibbs, Corrina; Tait, Joyce; Whitelaw, C Bruce A

2013-08-01

Scientific advances in methods of producing genetically modified (GM) animals continue, yet few such animals have reached commercial production. Existing regulations designed for early techniques of genetic modification pose formidable barriers to commercial applications. Radically improved techniques for producing GM animals invite a re-examination of current regulatory regimes. We critically examine current GM animal regulations, with a particular focus on the European Union, through a framework that recognises the importance of interactions among regulatory regimes, innovation outcomes and industry sectors. The current focus on the regulation of risk is necessary but is unable to discriminate among applications and tends to close down broad areas of application rather than facilitate innovation and positive industry interactions. Furthermore, the fields of innovative animal biosciences appear to lack networks of organisations with co-ordinated future oriented actions. Such networks could drive coherent programmes of innovation towards particular visions and contribute actively to the development of regulatory systems for GM animals. The analysis presented makes the case for regulatory consideration of each animal bioscience related innovation on the basis of the nature of the product itself and not the process by which it was developed.

The (Mathematical) Modeling Process in Biosciences.

PubMed

Torres, Nestor V; Santos, Guido

2015-01-01

In this communication, we introduce a general framework and discussion on the role of models and the modeling process in the field of biosciences. The objective is to sum up the common procedures during the formalization and analysis of a biological problem from the perspective of Systems Biology, which approaches the study of biological systems as a whole. We begin by presenting the definitions of (biological) system and model. Particular attention is given to the meaning of mathematical model within the context of biology. Then, we present the process of modeling and analysis of biological systems. Three stages are described in detail: conceptualization of the biological system into a model, mathematical formalization of the previous conceptual model and optimization and system management derived from the analysis of the mathematical model. All along this work the main features and shortcomings of the process are analyzed and a set of rules that could help in the task of modeling any biological system are presented. Special regard is given to the formative requirements and the interdisciplinary nature of this approach. We conclude with some general considerations on the challenges that modeling is posing to current biology.

Ethics in research.

PubMed

Bevan, Joan C

2007-04-01

This review will examine research ethics in the context of globalization of clinical trials and recent rapid developments in bioscience. It will focus on international ethical guidelines and the functions of research ethics review boards in research governance. Consent issues in genetic research, which must comply with privacy laws by protecting confidentiality and privacy of personal health data, will be discussed. There has been a rapid expansion of genomic and proteonomic research and biotechnology in the last decade. International ethical guidelines have been updated and the bioscience industry has developed ethics policies. At the same time, problems in academic anesthesia in the US and UK have been identified, leading to recommendations to train physician-scientists in anesthesia to stimulate research activity in the future. Anesthesiologists are joining interdisciplinary research teams and the concept of evidence-based translational research is emerging. Anesthesiologists are moving towards participation in interdisciplinary research teams. They are well placed to speed the translation of research discovery into clinical practice and provide evidence-based perioperative care. This review provides the ethical framework that anesthesiologists will need to meet the challenges of this changing pattern of practice.

Interactive problem-solving sessions in an introductory bioscience course engaged students and gave them feedback, but did not increase their exam scores.

PubMed

McEvoy, James P

2017-10-02

Active learning, including the promotion of student interactivity in lectures, has been found to improve student engagement and performance in university science classes. This letter describes the use of Pearson's Learning Catalytics to run regular, formatively assessed problem-solving sessions as part of the semiflipped redesign of an introductory level university bioscience course. Students found the problem-solving sessions more engaging than a traditional lecture, and felt that they were receiving better feedback on their progress in the course. Their participation in the problem-solving sessions was strongly associated with their performance in the course's summative assessments, making it possible to identify and assist probable poor performers early in the course. Other measures of student engagement with the course were not improved, and neither were their average exam grades when compared with their grades in a course which had not been redesigned. Possible reasons for this are discussed. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

The Notion of Scientific Knowledge in Biology

NASA Astrophysics Data System (ADS)

Morante, Silvia; Rossi, Giancarlo

2016-03-01

The purpose of this work is to reconsider and critically discuss the conceptual foundations of modern biology and bio-sciences in general, and provide an epistemological guideline to help framing the teaching of these disciplines and enhancing the quality of their presentation in High School, Master and Ph.D. courses. After discussing the methodological problems that arise in trying to construct a sensible and useful scientific approach applicable to the study of living systems, we illustrate what are the general requirements that a workable scheme of investigation should meet to comply with the principles of the Galilean method. The amazing success of basic physics, the Galilean science of election, can be traced back to the development of a radically " reductionistic" approach in the interpretation of experiments and a systematic procedure tailored on the paradigm of " falsifiability" aimed at consistently incorporating new information into extended models/theories. The development of bio-sciences seems to fit with neither reductionism (the deeper is the level of description of a biological phenomenon the more difficult looks finding general and simple laws), nor falsifiability (not always experiments provide a yes-or-no answer). Should we conclude that biology is not a science in the Galilean sense? We want to show that this is not so. Rather in the study of living systems, the novel interpretative paradigm of " complexity" has been developed that, without ever conflicting with the basic principles of physics, allows organizing ideas, conceiving new models and understanding the puzzling lack of reproducibility that seems to affect experiments in biology and in other modern areas of investigation. In the delicate task of conveying scientific concepts and principles to students as well as in popularising bio-sciences to a wider audience, it is of the utmost importance for the success of the process of learning to highlight the internal logical consistency of biology and its compliance with the fundamental laws of physics.

Instability of Hydrogenated TiO2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nandasiri, Manjula I.; Shutthanandan, V.; Manandhar, Sandeep

2015-11-06

Hydrogenated TiO2 (H-TiO2) is toted as a viable visible light photocatalyst. We report a systematic study on the thermal stability of H-implanted TiO2 using X-ray photoelectron spectroscopy (XPS), ultraviolet photoelectron spectroscopy (UPS), Rutherford backscattering spectrometry (RBS) and nuclear reaction analysis (NRA). Protons (40 keV) implanted at a ~2 atom % level within a ~120 nm wide profile of rutile TiO2(110) were situated ~300 nm below the surface. NRA revealed that this H-profile broadened preferentially toward the surface after annealing at 373 K, dissipated out of the crystal into vacuum at 473 K, and was absent within the beam sampling depthmore » (~800 nm) at 523 K. Photoemission showed that the surface was reduced in concert with these changes. Similar anneals had no effect on pristine TiO2(110). The facile bulk diffusivity of H in rutile, as well as its activity toward interfacial reduction, significantly limits the utilization of H-TiO2 as a photocatalyst. This work was supported by the US Department of Energy, Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences & Biosciences. Pacific Northwest National Laboratory (PNNL) is a multiprogram national laboratory operated for DOE by Battelle. The research was performed using the Environmental Molecular Sciences Laboratory (EMSL), a national scientific user facility sponsored by the Department of Energy's Office of Biological and Environmental Research and located at Pacific Northwest National Laboratory.« less

From "Hesitant" to "Environmental Leader": The Influence of a Professional Development Program on the Environmental Citizenship of Preschool Teachers

ERIC Educational Resources Information Center

Spektor-Levy, Ornit; Abramovich, Anat

2017-01-01

This study investigated the influence that the "Environmental Leadership Professional Development" program had on preschool teachers. The program's aim is to enhance environmental awareness, thus developing environmental citizenship and leadership. The program offered experiential and reflective learning, meetings with environmental…

Basic Energy Sciences FY 2011 Research Summaries

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

This report provides a collection of research abstracts for more than 1,300 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2011 at some 180 institutions across the U.S. This volume is organized along the three BES divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.

Career development for women scientists in Asia.

PubMed

Ip, Nancy Y

2011-06-23

Previously, challenges faced by women scientists have made it difficult for them to realize their dreams. The remarkable growth of Asian bioscience over the past decade, however, has created opportunities for young women in their home countries. The time is ripe for women in Asia to pursue their scientific aspirations. Copyright © 2011 Elsevier Inc. All rights reserved.

Sensitivity of S-Cat to Sleep Deprivation

DTIC Science & Technology

2006-01-01

DIRECTORATE BIOSCIENCES AND PROTECTION DVSION BIOBEHAVIORAL PERFORMANCE BRANCH 2485 GILLINGHAM DRIVE BROOKS CITY-BASE TX 78235 Approved for public...7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT Embry-Riddle Arrorautical CHII Systemns, Inc. NTI, Inc. Lyndon B...non-invasive means to objectively evaluate the cognitive ability of astronauts to perform ruission critical tasks, particularly during extended

Writing Activities Embedded in Bioscience Laboratory Courses to Change Students' Attitudes and Enhance Their Scientific Writing

ERIC Educational Resources Information Center

Lee, Susan E.; Woods, Kyra J.; Tonissen, Kathryn F.

2011-01-01

We introduced writing activities into a project style third year undergraduate biomolecular science laboratory to assist the students to produce a final report in the form of a journal article. To encourage writing while the experimental work was proceeding, the embedded writing activities required ongoing analysis of experimental data. After…

Scientists repurpose HPV vaccine technology to fight eye cancer | Center for Cancer Research

Cancer.gov

Uveal melanoma is a rare eye cancer that affects about 1,600 people in the United States. A study by scientists in the Center for Cancer Research and Aura Biosciences, Cambridge, Mass., published December 14, 2017, in Molecular Cancer Therapeutics, provides new hope for the early treatment of uveal melanoma. Read more…

The Findings of an Assessment Audit: An NTFS Project Report

ERIC Educational Resources Information Center

Hughes, Ian

2006-01-01

An Assessment Audit is described consisting of 47 questions, each being scored 0 to 4, by the module team depending on the extent to which the audit point was satisfied. Scores of 2 or less indicated unsatisfactory provision. Audits were carried out on 14 bioscience- or medicine-based modules in 13 universities. There was great variability between…

Attitudes to the Uses of Animals in Higher Education: Has Anything Changed?

ERIC Educational Resources Information Center

Donaldson, Lynda; Downie, Roger

2007-01-01

Bioscience staff and students at Glasgow University in session 2005-06 were questioned on their attitudes to animal uses in higher education, as follow-up to a similar survey 20 years before. Disapproval by students of animal use was generally reduced compared to 20 years ago, but students remained in a "moral bind", recognising the…

Decoupling Policy and Practice: How Life Scientists Respond to Ethics Education

ERIC Educational Resources Information Center

Smith-Doerr, Laurel

2008-01-01

Many graduate programmes in science now require courses in ethics. However, little is known about their reception or use. Using websites and interviews, this essay examines ethics requirements in the field of biosciences in three countries (the United States of America, the United Kingdom, and Italy) between 2000 and 2005. Evidence suggests that…

Hooked on Science: How an Ohio Teacher is Training Students to Be Linked in to Forensics

ERIC Educational Resources Information Center

Technology & Learning, 2008

2008-01-01

This article features Ohio teacher Carol Fleck's use of videoconferencing in teaching Contemporary BioScience and Genetics. Fleck, who says her initial vision for the class was "science without classroom walls," covers such topics as emerging diseases, bioterrorism, and forensic science. Collaboration between schools is a key part of the…

Basic Energy Sciences FY 2012 Research Summaries

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

This report provides a collection of research abstracts and highlights for more than 1,400 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2012 at some 180 institutions across the U.S. This volume is organized along the three BES Divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.

Basic Energy Sciences FY 2014 Research Summaries

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

This report provides a collection of research abstracts and highlights for more than 1,200 research projects funded by the Office of Basic Energy Sciences (BES) in Fiscal Year 2014 at some 200 institutions across the U.S. This volume is organized along the three BES Divisions: Materials Sciences and Engineering; Chemical Sciences, Geosciences, and Biosciences; and Scientific User Facilities.

SMRT sequencing of the Vitis vinifera cv. ‘Flame seedless’ genome using a SMRTbell-free library preparation from Swift Biosciences

USDA-ARS?s Scientific Manuscript database

Single Molecule Real-Time (SMRT) sequencing provides advantages to the sequencing of complex genomes. The long reads generated are superior for resolving complex genomic regions and provide highly contiguous de novo assemblies. Current SMRTbell libraries generate average read lengths of 10-15kb. How...

An Expanded Framework for Biomolecular Visualization in the Classroom: Learning Goals and Competencies

ERIC Educational Resources Information Center

Dries, Daniel R.; Dean, Diane M.; Listenberger, Laura L.; Novak, Walter R. P.; Franzen, Margaret A.; Craig, Paul A.

2017-01-01

A thorough understanding of the molecular biosciences requires the ability to visualize and manipulate molecules in order to interpret results or to generate hypotheses. While many instructors in biochemistry and molecular biology use visual representations, few indicate that they explicitly teach visual literacy. One reason is the need for a list…

Perceptions of Play: Using Play-Doh to Enhance the Student Experience in Bioscience Higher Education

ERIC Educational Resources Information Center

Lace-Costigan, Gemma

2017-01-01

Playful and kinaesthetic learning approaches are used in numerous early years (birth to 5 years old) learning environments, however studies in HE STEM disciplines are uncommon. This study aimed to explore the use of Play-Doh in an undergraduate anatomy module as a method of enhancing engagement. 63 students attended the "kinaesthetic…

Approaches to the Teaching of Bioethics and Professional Ethics in Undergraduate Courses

ERIC Educational Resources Information Center

Downie, Roger; Clarkeburn, Henriikka

2005-01-01

The role of ethics in bioscience undergraduate degrees is now widely accepted, but how ethics should be taught, who should teach it and what the curriculum should include are matters for debate. This article discusses teaching strategies: specialist options, or embed ethics in other courses, or both; use of professional philosophers, or…

The "Ethics Committee": A Practical Approach to Introducing Bioethics and Ethical Thinking

ERIC Educational Resources Information Center

Goodwin, Mark; Kramer, Cas; Cashmore, Annette

2012-01-01

Bioethics is an increasingly important part of the biosciences curriculum at school and in higher education, but few science teachers have much experience of teaching the subject in an engaging or interactive manner. This article sets out a session that allows students to practise the skills of ethical thinking and ethical debate in a relevant…

Secondary School Science Predictors of Academic Performance in University Bioscience Subjects

ERIC Educational Resources Information Center

Green, Rod; Brown, Elizabeth; Ward, Alex

2009-01-01

In 2009 the Faculty of Health Sciences at La Trobe University in Melbourne, Australia is introducing a common first year for 11 different undergraduate courses in the faculty. Current prerequisite science entry requirements vary with course and range from none to at least two science or mathematics subjects and from [approximately]50 to 99 in…

CTC-Endothelial Cell Interactions during Metastasis

DTIC Science & Technology

2014-06-01

antibody. For these experiments, we first tested the Bioflux Microfluidics system. In our hands, the Bioflux microfluidic system was suboptimal for...indicated in the results, a subset of rolling assay experiments were also performed using Bioflux Microfluidics technologies (Fluxion Biosciences...behavior of MDA cells in the presence of neutralizing anti-E-selectin antibody. We performed these experiments using Bioflux Microfluidics technology

Using Capstones to Develop Research Skills and Graduate Capabilities: A Case Study from Physiology

ERIC Educational Resources Information Center

Julien, Brianna L.; Lexis, Louise; Schuijers, Johannes; Samiric, Tom; McDonald, Stuart

2012-01-01

In 2011, the Department of Human Biosciences introduced two physiology capstone subjects as part of the Design for Learning Project at La Trobe University. Consistent with the project, the aims of these subjects were to provide an effective culmination point for the Bachelor of Health Science course and to offer students orientation to…

Factors Affecting Student Choice of the Undergraduate Research Project: Staff and Student Perceptions

ERIC Educational Resources Information Center

Harland, Janice; Pitt, Sarah; Saunders, Venetia

2005-01-01

As pressures on resources are growing and some question the value and types of final year research work for students in the biosciences and other disciplines, it is important to be well informed about student expectations of their project. In this case study within Biomolecular Sciences, questionnaires were used to compare staff and student…

76 FR 44309 - Notice of Intent To Grant a Partially Exclusive Patent License; TransMembrane Bioscience, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-25

... Coxiella burnetii; U.S. Patent No. 7,824,875: Recombinant antigens for the detection of Coxiella burnetii; and U.S. Patent No. 7,824,909: Recombinant antigens for the detection of Coxiella burnetii in the... Coxiella burnetii infection by antibody-based assays using recombinant, immunodominant C. burnetii...

Closing the Social Class Achievement Gap for First-Generation Students in Undergraduate Biology

ERIC Educational Resources Information Center

Harackiewicz, Judith M.; Canning, Elizabeth A.; Tibbetts, Yoi; Giffen, Cynthia J.; Blair, Seth S.; Rouse, Douglas I.; Hyde, Janet S.

2014-01-01

Many students start college intending to pursue a career in the biosciences, but too many abandon this goal because they struggle in introductory biology. Interventions have been developed to close achievement gaps for underrepresented minority students and women, but no prior research has attempted to close the gap for first-generation students,…

Biotechnology at the Cutting Edge - Keasling

ScienceCinema

Keasling, Jay

2018-05-11

Jay Keasling, Berkeley Lab ALD for Biosciences and CEO of the Joint BioEnergy Institute, appears in a video on biotechnology at the Smithsonian's National Museum of American History. The video is part of en exhibit titled "Science in American Life," which examines the relationship between science, technology, progress and culture through artifacts, historical photographs and multimedia technology.

The returning tide: how China, the world's most populous country, is building a competitive research base.

PubMed

Wells, William A

2007-02-19

When China turned its back on the Cultural Revolution, it aimed to build a thriving capitalist sector. It got one. Now, it wants a world-class research enterprise. How far has it progressed in the biosciences, how did it get there, and how far does it have to go?

The mitochondrial genome of a Texas outbreak strain of the cattle tick, Rhipicephalus (Boophilus) microplus, derived from whole genome sequencing Pacific Biosciences and Illumina reads

USDA-ARS?s Scientific Manuscript database

The cattle fever tick, Rhipicephalus (Boophilus) microplus is one of the most significant medical veterinary pests in the world, vectoring several serious livestock diseases negatively impacting agricultural economies of tropical and subtropical countries around the world. We assembled the complete ...

Using Explicit Teaching to Improve How Bioscience Students Write to the Lay Public

ERIC Educational Resources Information Center

Moni, Roger W.; Hryciw, Deanne H.; Poronnik, Philip; Moni, Karen B.

2007-01-01

The media role model was recently developed to frame how science faculty members can teach their students to write more effectively to lay audiences (14). An Opinion Editorial (Op-Ed) was introduced as a novel assignment for final-year physiology and pharmacology undergraduates. This second phase of this study, reported here, demonstrated the…

"Cancer Cell Biology:" A Student-Centered Instructional Module Exploring the Use of Multimedia to Enrich Interactive, Constructivist Learning of Science

ERIC Educational Resources Information Center

Bockholt, Susanne M.; West, J. Paige; Bollenbacher, Walter E.

2003-01-01

Multimedia has the potential of providing bioscience education novel learning environments and pedagogy applications to foster student interest, involve students in the research process, advance critical thinking/problem-solving skills, and develop conceptual understanding of biological topics. "Cancer Cell Biology," an interactive, multimedia,…

U.S. Army Research Laboratory 2010 Annual Review

DTIC Science & Technology

2010-12-01

Translation Between Scales battlefield neuroscience Neuro-Cognitive Measurement Cognitive/Information – Decision Making Neurally Inspired Systems...the areas of Bioscience, Neuroscience , Network Science of Decision Making, Nanoscience, GaN High Power Electronics, Power for Microsystems, Graphene...source project POF, and NSA Trickler have also demonstrated that networks can be understood through passive observation of traffic as it exits a

Recruitment and Retention of Students--An Integrated and Holistic Vision of Mathematics Support

ERIC Educational Resources Information Center

Croft, A. C.; Harrison, M. C.; Robinson, C. L.

2009-01-01

Students' lack of preparedness for the mathematical demands of higher education is affecting a wide range of programmes in universities worldwide. In the UK this has been recognized at the highest levels and provoked several inquiries. The ability to use mathematics in courses as varied as nursing, biosciences, and business is an essential skill…

Academic Performance and Pass Rates: Comparison of Three First-Year Life Science Courses

ERIC Educational Resources Information Center

Downs, C. T.

2009-01-01

First year students' academic performance in three Life Science courses (Botany, Zoology and Bioscience) was compared. Pass rates, as well as the means and distributions of final marks were analysed. Of the three components (coursework, practical and theory examinations) contributing to the final mark of each course, students performed best in the…

Making Bioinformatics Projects a Meaningful Experience in an Undergraduate Biotechnology or Biomedical Science Programme

ERIC Educational Resources Information Center

Sutcliffe, Iain C.; Cummings, Stephen P.

2007-01-01

Bioinformatics has emerged as an important discipline within the biological sciences that allows scientists to decipher and manage the vast quantities of data (such as genome sequences) that are now available. Consequently, there is an obvious need to provide graduates in biosciences with generic, transferable skills in bioinformatics. We present…

21 CFR 212.5 - To what drugs do the regulations in this part apply?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 210 and 211 of this chapter. (b) Investigational and research PET drugs. For investigational PET drugs... this chapter, and PET drugs produced with the approval of a Radioactive Drug Research Committee in... Biosciences Library, 10903 New Hampshire Ave., Silver Spring, MD, 20993-0002, 301-796-3504, or at the National...

21 CFR 212.5 - To what drugs do the regulations in this part apply?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 210 and 211 of this chapter. (b) Investigational and research PET drugs. For investigational PET drugs... this chapter, and PET drugs produced with the approval of a Radioactive Drug Research Committee in... Biosciences Library, 10903 New Hampshire Ave., Silver Spring, MD, 20993-0002, 301-796-3504, or at the National...

21 CFR 212.5 - To what drugs do the regulations in this part apply?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 210 and 211 of this chapter. (b) Investigational and research PET drugs. For investigational PET drugs... this chapter, and PET drugs produced with the approval of a Radioactive Drug Research Committee in... Biosciences Library, 10903 New Hampshire Ave., Silver Spring, MD, 20993-0002, 301-796-3504, or at the National...

21 CFR 212.5 - To what drugs do the regulations in this part apply?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 210 and 211 of this chapter. (b) Investigational and research PET drugs. For investigational PET drugs... this chapter, and PET drugs produced with the approval of a Radioactive Drug Research Committee in... Biosciences Library, 10903 New Hampshire Ave., Silver Spring, MD, 20993-0002, 301-796-3504, or at the National...

Trends in Environmental Health Engineering

ERIC Educational Resources Information Center

Rowe, D. R.

1972-01-01

Reviews the trends in environmental health engineering and describes programs in environmental engineering technology and the associated environmental engineering courses at Western Kentucky University (four-year program), Wytheville Community College (two-year program), and Rensselaer Polytechnic Institute (four-year program). (PR)

Environmental Sciences Division annual progress report for period ending September 30, 1981

DOE Office of Scientific and Technical Information (OSTI.GOV)

Auerbach, S.I.; Reichle, D.E.

1982-04-01

Research programs from the following sections and programs are summarized: aquatic ecology, environmental resources, earth sciences, terrestrial ecology, advanced fossil energy program, toxic substances program, environmental impacts program, biomass, low-level waste research and development program, US DOE low-level waste management program, and waste isolation program.

Peptoid Backbone Flexibilility Dictates Its Interaction with Water and Surfaces: A Molecular Dynamics Investigation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prakash, Arushi; Baer, Marcel D.; Mundy, Christopher J.

Peptoids are peptide-mimetic biopolymers that are easy-to-synthesize and adaptable for use in drugs, chemical scaffolds, and coatings. However, there is insufficient information about their structural preferences and interactions with the environment in various applications. We conducted a study to understand the fundamental differences between peptides and peptoids using molecular dynamics simulations with semi-empirical (PM6) and empirical (AMBER) potentials, in conjunction with metadynamics enhanced sampling. From studies of single molecules in water and on surfaces, we found that sarcosine (model peptoid) is much more flexible than alanine (model peptide) in different environments. However, the sarcosine and alanine interact similarly with amore » hydrophobic or a hydrophilic. Finally, this study highlights the conformational landscape of peptoids and the dominant interactions that drive peptoids towards these conformations. ACKNOWLEDGMENT: MD simulations and manuscript preparation were supported by the MS3 (Materials Synthesis and Simulation Across Scales) Initiative at Pacific Northwest National Laboratory (PNNL), a multi-program national laboratory operated by Battelle for the U.S. Department of Energy. CJM was supported by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences Division of Chemical Sciences, Geosciences, and Biosciences. MDB was supported by the US Department of Energy, Office of Basic Energy Sciences, Biomolecular Materials Program at PNNL. Computing resources were generously allocated by University of Washington's IT department and PNNL's Institutional Computing program. The authors greatly acknowledge conversations with Dr. Kayla Sprenger, Josh Smith, and Dr. Yeneneh Yimer.« less

The Envirothon and its effects on students' environmental literacy

NASA Astrophysics Data System (ADS)

Weiser, Brenda Gayle

During the past thirty years, significant progress has been made in defining environmental education and its goals, and operationally by the emerging concept of environmental literacy. Environmental literacy includes affective, behavioral, and cognitive components. Roth (1992) includes environmental sensitivity, knowledge, skills, attitudes and values, personal investment and responsibility, and active involvement as components of environmental literacy. In addition, Simmons (1995) identifies affect, ecological knowledge, socio-political knowledge, knowledge of environmental issues, skills, environmentally responsible behaviors, and additional determinants of environmentally responsible behaviors as components of environmental literacy. Environmental education is the primary vehicle for promoting environmental literacy. Most K through 12 environmental education is delivered in non-formal programs outside traditional curriculum and instruction and is exemplified by the National Envirothon program. Student teams compete to demonstrate their knowledge and understanding of ecological principles in aquatics, forestry, soils, wildlife, and a selected environmental issue. Each year over 75,000 high school students participate in the Envirothon. The purpose of the study was to identify the effects of Envirothon participation on its high school students from 17 out of 43 states with Envirothon programs. One hundred forty eight students completed the Wisconsin Environmental Literacy Assessment Instrument; (Peri, 1996), to assess their environmental literacy status. Data were analyzed using an analysis of covariance where the pretest was the covariate. The results indicated the participation in the Envirothon program does make a statistically significant difference between the environmental literacy of those high school students who have participated in the Envirothon program and the environmental literacy of those high school students who have not participated in the Envirothon program in the cognitive component of environmental literacy but does not in the affective and behavioral components of environmental literacy. Results also indicated there was not a statistically significant difference between the environmental literacy of those high school students who have participated in one or more Envirothon competitions and the environmental literacy of those high school students who have participated in less than one Envirothon competition in regard to the cognitive, affective, or behavior components of environmental literacy. The implication is participating in the Envirothon program does make a difference in the environmental literacy of those high school students participating in the Envirothon program in the cognitive component of environmental literacy but participating in the Envirothon program does not increase the environmental literacy of those high school students participating in the Envirothon program in the affective or behavioral components of environmental literacy. This information is important to teachers, advisors, state and national Envirothon committee members, and sponsors relating to the international goals, objectives and key points, study materials, and training methodology as each is used to expand and strengthen Envirothon programs. Furthermore, many fenders are interested in the program and how it is affecting the students. Recommendations for further research include conducting a meta-analysis using this research and the research conducted by Meredith (1996), longitudinal studies, and case studies utilizing past Envirothon students. Documentation through news articles and interviews could assist in assessing the Envirothon program's impact on students. This would not evaluate the student's environmental literacy, but would provide information on how the Envirothon program influences students' life choices.

Elementary Steps of Faujasite Formation Followed by in Situ Spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prodinger, Sebastian; Vjunov, Aleksei; Hu, Jian Zhi

Ex situ and in situ spectroscopy was used to identify the kinetics of processes during the formation of the faujasite (FAU) zeolite lattice from a hydrous gel. Using solid-state 27Al MAS NMR, the autocatalytic transformation from the amorphous gel into the crystalline material was monitored. Al-XANES shows that most Al already adopts a tetrahedral coordination in the X-ray-amorphous aluminosilicate at the beginning of the induction period, which hardly changes throughout the rest of the synthesis. Using 23Na NMR spectroscopy, environments in the growing zeolite crystal were identified and used to define the processes in the stepwise formation of the zeolitemore » lattice. The end of the induction period was accompanied by a narrowing of the 27Al and 23Na MAS NMR peak widths, indicating the increased long-range order. The experiments show conclusively that the formation of faujasite occurs via the continuous formation and subsequent condensation of intermediary sodalite-like units that constitute the key building block of the zeolite. Acknowledgement The authors thank T. Huthwelker for assistance with XAFS experiment setup at the Swiss Light Source (PSI, Switzerland). Further, we would like to acknowledge V. Shutthanandan and B.W. Arey for performing Helium ion microscopy as well as Z. Zhao, N.R. Jaeger, M. Weng, C. Wan and M. Hu for aiding in the NMR experimental procedure. T. Varga is acknowledged for his help with the capillary XRD. A.V., D.M.C., J.H., J.L.F and J.A.L. were supported by the US Department of Energy, Office of Science, Office of Basic Energy Sciences. S.P. and M.A.D. acknowledge support by the Materials Synthesis and Simulation Across Scales (MS3 Initiative) conducted under Laboratory Directed Research & Development Program at PNNL. The in situ NMR experiments were supported by the U. S. Department of Energy (DOE), Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Biosciences and Geosciences. Part of the research described in this paper was performed in the Environmental Molecular Sciences Laboratory (EMSL), a national scientific user facility sponsored by the DOE’s Office of Biological and Environmental Research and located at Pacific Northwest National Laboratory (PNNL). PNNL is operated for the US DOE by Battelle.« less

7 CFR 1700.30 - Water and Environmental Programs.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 11 2011-01-01 2011-01-01 false Water and Environmental Programs. 1700.30 Section..., DEPARTMENT OF AGRICULTURE GENERAL INFORMATION Agency Organization and Functions § 1700.30 Water and Environmental Programs. RUS, through the Water and Environmental Programs, provides loan and grant funds for...

7 CFR 1700.30 - Water and Environmental Programs.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 11 2014-01-01 2014-01-01 false Water and Environmental Programs. 1700.30 Section..., DEPARTMENT OF AGRICULTURE GENERAL INFORMATION Agency Organization and Functions § 1700.30 Water and Environmental Programs. RUS, through the Water and Environmental Programs, provides loan and grant funds for...

7 CFR 1700.30 - Water and Environmental Programs.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 11 2012-01-01 2012-01-01 false Water and Environmental Programs. 1700.30 Section..., DEPARTMENT OF AGRICULTURE GENERAL INFORMATION Agency Organization and Functions § 1700.30 Water and Environmental Programs. RUS, through the Water and Environmental Programs, provides loan and grant funds for...

7 CFR 1700.30 - Water and Environmental Programs.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 11 2013-01-01 2013-01-01 false Water and Environmental Programs. 1700.30 Section..., DEPARTMENT OF AGRICULTURE GENERAL INFORMATION Agency Organization and Functions § 1700.30 Water and Environmental Programs. RUS, through the Water and Environmental Programs, provides loan and grant funds for...

Environmental education mentoring and continuing education programs -- A progress report on programs implemented by the Partnership for Environmental Technology Education (PETE)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arenstein, W.A.

1999-07-01

This paper will discuss environmental education mentoring and continuing education programs that are being implemented by the Partnership for Environmental Technology Education (PETE) organization. PETE is a national organization whose purpose is to promote quality environmental training and education by operating cooperative programs that enhance partnerships between community colleges, business and industry, and government. The first program is the Faculty Associate in Science and Technology, or FAST program. The goal of this program is to offer professional internships to environmental science and technology college instructors. Funded by a grant from the National Science Foundation, this program has offered over 150more » internships during the last 3 years. College instructors were placed with a variety of host sites, including private companies, environmental consulting companies, federal laboratories, and environmental regulatory agencies. They worked from 4--8 weeks side-by-side with environmental professionals in a variety of fields. The program has two main goals, first, to provide college instructors with the latest environmental information and techniques available so they can incorporate them into their course curriculum. The second goal is for the instructors to gather information from the organizations they intern with as to the kinds of knowledge and skills they want in their future environmental employees. The college instructors can then modify their curriculum and degree programs to better reflect the needs of employers. Additionally, these internships provide the opportunity for college instructors to enter into mentoring relationships with real world environmental professionals. The second program involves the annual continuing education conferences held by regional PETE offices during the school year.« less

Teaching science content in nursing programs in Australia: a cross-sectional survey of academics.

PubMed

Birks, Melanie; Ralph, Nicholas; Cant, Robyn; Hillman, Elspeth; Chun Tie, Ylona

2015-01-01

Professional nursing practice is informed by biological, social and behavioural sciences. In undergraduate pre-registration nursing programs, biological sciences typically include anatomy, physiology, microbiology, chemistry, physics and pharmacology. The current gap in the literature results in a lack of information about the content and depth of biological sciences being taught in nursing curricula. The aim of this study was to establish what priority is given to the teaching of science topics in these programs in order to inform an understanding of the relative importance placed on this subject area in contemporary nursing education. This study employed a cross-sectional survey method. This paper reports on the first phase of a larger project examining science content in nursing programs. An existing questionnaire was modified and delivered online for completion by academics who teach science to nurses in these programs. This paper reports on the relative priority given by respondents to the teaching of 177 topics contained in the questionnaire. Of the relatively small population of academics who teach science to nursing students, thirty (n = 30) completed the survey. Findings indicate strong support for the teaching of science in these programs, with particular priority given to the basic concepts of bioscience and gross system anatomy. Of concern, most science subject areas outside of these domains were ranked as being of moderate or low priority. While the small sample size limited the conclusions able to be drawn from this study, the findings supported previous studies that indicated inadequacies in the teaching of science content in nursing curricula. Nevertheless, these findings have raised questions about the current philosophy that underpins nursing education in Australia and whether existing practices are clearly focused on preparing students for the demands of contemporary nursing practice. Academics responsible for the design and implementation of nursing curricula are encouraged to review the content of current programs in light of the findings of this research.

Intervention, integration and translation in obesity research: Genetic, developmental and metaorganismal approaches

PubMed Central

2011-01-01

Obesity is the focus of multiple lines of inquiry that have -- together and separately -- produced many deep insights into the physiology of weight gain and maintenance. We examine three such streams of research and show how they are oriented to obesity intervention through multilevel integrated approaches. The first research programme is concerned with the genetics and biochemistry of fat production, and it links metabolism, physiology, endocrinology and neurochemistry. The second account of obesity is developmental and draws together epigenetic and environmental explanations that can be embedded in an evolutionary framework. The third line of research focuses on the role of gut microbes in the production of obesity, and how microbial activities interact with host genetics, development and metabolism. These interwoven explanatory strategies are driven by an orientation to intervention, both for experimental and therapeutic outcomes. We connect the integrative and intervention-oriented aspects of obesity research through a discussion of translation, broadening the concept to capture the dynamic, iterative processes of scientific practice and therapy development. This system-oriented analysis of obesity research expands the philosophical scrutiny of contemporary developments in the biosciences and biomedicine, and has the potential to enrich philosophy of science and medicine. PMID:21276254

Graphene Oxide Catalyzed C-H Bond Activation: The Importance Oxygen Functional Groups for Biaryl Construction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gao, Yongjun; Tang, Pei; Zhou, Hu

A heterogeneous, inexpensive and environment-friendly carbon catalytic system was developed for the C-H bond arylation of benzene resulting in the subsequent formation of biaryl compounds. The oxygen-containing groups on these graphene oxide sheets play an essential role in the observed catalytic activity. The catalytic results of model compounds and DFT calculations show that these functional groups promote this reaction by stabilization and activation of K ions at the same time of facilitating the leaving of I. And further mechanisms studies show that it is the charge induced capabilities of oxygen groups connected to specific carbon skeleton together with the giantmore » π-reaction platform provided by the π-domain of graphene that played the vital roles in the observed excellent catalytic activity. D. Mei acknowledges the support from the US Department of Energy (DOE), Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences & Biosciences. Pacific Northwest National Laboratory (PNNL) is a multiprogram national laboratory operated for DOE by Battelle. Computing time was granted by the grand challenge of computational catalysis of the William R. Wiley Environmental Molecular Sciences Laboratory.« less

PipeCraft: Flexible open-source toolkit for bioinformatics analysis of custom high-throughput amplicon sequencing data.

PubMed

Anslan, Sten; Bahram, Mohammad; Hiiesalu, Indrek; Tedersoo, Leho

2017-11-01

High-throughput sequencing methods have become a routine analysis tool in environmental sciences as well as in public and private sector. These methods provide vast amount of data, which need to be analysed in several steps. Although the bioinformatics may be applied using several public tools, many analytical pipelines allow too few options for the optimal analysis for more complicated or customized designs. Here, we introduce PipeCraft, a flexible and handy bioinformatics pipeline with a user-friendly graphical interface that links several public tools for analysing amplicon sequencing data. Users are able to customize the pipeline by selecting the most suitable tools and options to process raw sequences from Illumina, Pacific Biosciences, Ion Torrent and Roche 454 sequencing platforms. We described the design and options of PipeCraft and evaluated its performance by analysing the data sets from three different sequencing platforms. We demonstrated that PipeCraft is able to process large data sets within 24 hr. The graphical user interface and the automated links between various bioinformatics tools enable easy customization of the workflow. All analytical steps and options are recorded in log files and are easily traceable. © 2017 John Wiley & Sons Ltd.

Biocatalysis and biomimetics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burrington, J.D.; Clark, D.S.

1989-01-01

The proceedings are divided into three parts: Bioscience and biotechnology; Structure-function relationships; and Biomimetics. Topics include: the chemistry of biotechnology, biomimetics, and biocatalysts; crystallography and mutagenesis; computerized simulation of biocatalysis and biomimetic processes; enzymatic reactions in micellar systems; hydroxylation of hydrocarbons; oxidation of lignin; zeolite catalysts as enzyme mimics; and immobilization of proteins and enzymes. Some papers have been processed separately for inclusion on the data base.

Reducing Enzyme Costs Increases the Market Potential of Biofuels (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Cellulosic ethanol prices depend heavily on the cost of the cellulase enzymes used to break down the biomass into fermentable sugars. To reduce these costs, NREL partnered with two leading enzyme companies, Novozymes and Genencor, to engineer new cellulase enzymes that are exceptionally good at breaking down cellulose. Genencor is now part of DuPont Industrial Biosciences.

Integrin Alpha-v and HER2 in Breast Cancer Brain Metastasis

DTIC Science & Technology

2015-10-01

ZOOM live cell imaging machine (ESSEN Bioscience; Figure 2). c. Interactions of αv integrin and HER2 in breast cancer brain metastases. We found...HCC1954 breast cancer cells. C) Real time live cell imaging of MM2BH cells treated with cilengitide (0, .3, 1, 3, and 10 µg/mL) using IncuCyte ZOOM

Case Studies of Leading Edge Small Urban High Schools. Relevance Strategic Designs: 5. Life Academy of Health and Bioscience

ERIC Educational Resources Information Center

Shields, Regis Anne; Ireland, Nicole; City, Elizabeth; Derderian, Julie; Miles, Karen Hawley

2008-01-01

This report is one of nine detailed case studies of small urban high schools that served as the foundation for the Education Resource Strategies (ERS) report "Strategic Designs: Lessons from Leading Edge Small Urban High Schools." These nine schools were dubbed "Leading Edge Schools" because they stand apart from other high…

Taking Nanomedicine Teaching into Practice with Atomic Force Microscopy and Force Spectroscopy

ERIC Educational Resources Information Center

Carvalho, Filomena A.; Freitas, Teresa; Santos, Nuno C.

2015-01-01

Atomic force microscopy (AFM) is a useful and powerful tool to study molecular interactions applied to nanomedicine. The aim of the present study was to implement a hands-on atomic AFM course for graduated biosciences and medical students. The course comprises two distinct practical sessions, where students get in touch with the use of an atomic…

Rapid detection and classification of Salmonella enterica shedding in feedlot cattle utilizing Roka Bioscience Atlas Salmonella detection assay for the analysis of rectoanal mucosal swabs

USDA-ARS?s Scientific Manuscript database

With an increasing focus on preharvest food safety, rapid methods are required for the detection and quantification of foodborne pathogens such as Salmonella enterica in beef cattle. We validated the Atlas Salmonella Detection Assay (SEN), a nucleic acid amplification technology that targets Salmone...

Time Based Subjective Evaluations of Seated Cushion Comfort

DTIC Science & Technology

2007-04-01

Protection Division Biomechanics Branch Hilary L. Gallagher, MS Oak Ridge Institute for Science and Education (ORISE) 1299 Bethel Valley Road...MONITOR’S REPORT NUMBER(S) Biosciences and Protection Division AFRL-HE-WP-TR-2007-0062 Biomechanics Branch Wright-Patterson AFB OH 45433-7947 12...13 iv PREFACE The cushion comfort tests and data analysis described in this report were accomplished by the Biomechanics

The Effects of Ejection Seat Cushion Design on Physical Fatigue and Cognitive Performance

DTIC Science & Technology

2006-11-01

Protection Division Biomechanics Branch Wright-Patterson AFB Ohio 45433-7947 Approved for public release; distribution is unlimited. NOTICE...ADDRESS(ES *Air Force Materiel Command Air Force Research Laboratory Human Effectiveness Directorate Biosciences & Protection Division Biomechanics ...Dayton, Ohio. Analyses of the data were accomplished by the Biomechanics Branch, Human Effectiveness Directorate of the Air Force Research Laboratory

Quantitative Skills as a Graduate Learning Outcome of University Science Degree Programmes: Student Performance Explored through the "Planned-Enacted-Experienced" Curriculum Model

ERIC Educational Resources Information Center

Matthews, Kelly E.; Adams, Peter; Goos, Merrilyn

2016-01-01

Application of mathematical and statistical thinking and reasoning, typically referred to as quantitative skills, is essential for university bioscience students. First, this study developed an assessment task intended to gauge graduating students' quantitative skills. The Quantitative Skills Assessment of Science Students (QSASS) was the result,…

An "in silico" Bioinformatics Laboratory Manual for Bioscience Departments: "Prediction of Glycosylation Sites in Phosphoethanolamine Transferases"

ERIC Educational Resources Information Center

Alyuruk, Hakan; Cavas, Levent

2014-01-01

Genomics and proteomics projects have produced a huge amount of raw biological data including DNA and protein sequences. Although these data have been stored in data banks, their evaluation is strictly dependent on bioinformatics tools. These tools have been developed by multidisciplinary experts for fast and robust analysis of biological data.…

Supporting the Development of Undergraduates' Experimental Design Skills and Investigating their Perceptions of Project Work

ERIC Educational Resources Information Center

MacKenzie, Jane; Ruxton, Graeme

2006-01-01

Project work represents a significant component of most Bioscience degrees. Conscious that students are not necessarily given adequate preparation for their final year project, we have investigated two core elements in the 3rd year of a 4-year Honours programme. One element, an investigative project on aspects of insect biology, has run for…

The Impact of Attaining the Welsh Baccalaureate Advanced Diploma on Academic Performance in Bioscience Higher Education

ERIC Educational Resources Information Center

Yhnell, Emma; Wood, Heather; Baker, Mathew; Amici-Dargan, Sheila; Taylor, Chris; Randerson, Peter; Shore, Andrew

2016-01-01

Since the introduction of the Welsh Baccalaureate Advanced Diploma Qualification (WBQ) in 2003, an increasing number of students are applying to higher education institutions (HEIs) with this qualification. The advanced-level WBQ is regarded as equivalent to one General Certificate of Education A-Level (GCE A-Level). This study assesses the impact…

Inventory of Innovative Learning Materials in Marine Science and Technology. UNESCO Reports in Marine Science 60.

ERIC Educational Resources Information Center

Richards, Adrian F.; Richards, Efrosine A.

The Inventory of Innovative Learning Materials in Marine Science and Technology includes 32 computer-, 148 video-, 16 film-, and 11 CD-ROM-based entries. They concern materials in biosciences (67), chemistry (5), geosciences (16), physics (23), technology (76) and other (20). This first, initial compilations is conceived as the basis for more…

Improving the Effectiveness and Efficiency of Teaching Large Classes: Development and Evaluation of a Novel e-Resource in Cancer Biology

ERIC Educational Resources Information Center

Hejmadi, Momna V.

2007-01-01

This paper describes the development and evaluation of a blended learning resource in the biosciences, created by combining online learning with formal face-face lectures and supported by formative assessments. In order to improve the effectiveness and efficiency of teaching large classes with mixed student cohorts, teaching was delivered through…

Students' Knowledge of, and Attitudes towards Biotechnology Revisited, 1995-2014: Changes in Agriculture Biotechnology but Not in Medical Biotechnology

ERIC Educational Resources Information Center

Chen, Shao-Yen; Chu, Yih-Ru; Lin, Chen-Yung; Chiang, Tzen-Yuh

2016-01-01

Modern biotechnology is one of the most important scientific and technological revolutions in the 21st century, with an increasing and measurable impact on society. Development of biotechnology curriculum has become important to high school bioscience classrooms. This study has monitored high school students in Taiwan on their knowledge of and…

The Complex Relationship between Students' Critical Thinking and Epistemological Beliefs in the Context of Problem Solving

ERIC Educational Resources Information Center

Hyytinen, Heidi; Holma, Katariina; Toom, Auli; Shavelson, Richard J.; Lindblom-Ylänne, Sari

2014-01-01

The study utilized a multi-method approach to explore the connection between critical thinking and epistemological beliefs in a specific problem-solving situation. Data drawn from a sample of ten third-year bioscience students were collected using a combination of a cognitive lab and a performance task from the Collegiate Learning Assessment…

77 FR 56175 - Arcadia Biosciences, Inc.; Filing of Food Additive Petition (Animal Use)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-12

... additive regulations be amended to provide for the safe use in dry dog food of oil from a variety of... the safe use in dry dog food of oil from a variety of bioengineered safflower (Carthamus tinctorius L... will be used as a source of omega-6 fatty acids in dry food for adult dogs. The petitioner has...

Synthetic Biology between Self-Regulation and Public Discourse: Ethical Issues and the Many Roles of the Ethicist.

PubMed

Arnason, Gardar

2017-04-01

This article discusses the roles of ethicists in the governance of synthetic biology. I am particularly concerned with the idea of self-regulation of bioscience and its relationship to public discourse about ethical issues in bioscience. I will look at the role of philosophical ethicists at different levels and loci, from the "embedded ethicist" in the laboratory or research project, to ethicists' impact on policy and public discourse. In a democratic society, the development of governance frameworks for emerging technologies, such as synthetic biology, needs to be guided by a well-informed public discourse. In the case of synthetic biology, the public discourse has to go further than merely considering technical issues of biosafety and biosecurity, or risk management, to consider more philosophical issues concerning the meaning and value of "life" between the natural and the synthetic. I argue that ethicists have moral expertise to bring to the public arena, which consists not only in guiding the debate but also in evaluating arguments and moral positions and making normative judgments. When ethicists make normative claims or moral judgments, they must be transparent about their theoretical positions and basic moral standpoints.

The (Mathematical) Modeling Process in Biosciences

PubMed Central

Torres, Nestor V.; Santos, Guido

2015-01-01

In this communication, we introduce a general framework and discussion on the role of models and the modeling process in the field of biosciences. The objective is to sum up the common procedures during the formalization and analysis of a biological problem from the perspective of Systems Biology, which approaches the study of biological systems as a whole. We begin by presenting the definitions of (biological) system and model. Particular attention is given to the meaning of mathematical model within the context of biology. Then, we present the process of modeling and analysis of biological systems. Three stages are described in detail: conceptualization of the biological system into a model, mathematical formalization of the previous conceptual model and optimization and system management derived from the analysis of the mathematical model. All along this work the main features and shortcomings of the process are analyzed and a set of rules that could help in the task of modeling any biological system are presented. Special regard is given to the formative requirements and the interdisciplinary nature of this approach. We conclude with some general considerations on the challenges that modeling is posing to current biology. PMID:26734063

Integrating psychology with interpersonal communication skills in undergraduate nursing education: addressing the challenges.

PubMed

McCarthy, Bridie; Trace, Anna; O'Donovan, Moira

2014-05-01

The inclusion of the social, behavioural and bio-sciences is acknowledged as essential to the development of the art and science of nursing. Nonetheless, the literature highlights on-going debate about the content and delivery of these subject areas in undergraduate nursing education. The bio-sciences and social sciences in particular have received much attention but more recently the inclusion of psychology in nursing curricula is gaining momentum. Studies conducted on nursing students' views of these supporting sciences have also highlighted problems with their understanding, relevance and application to nursing practice. Although broad guidelines are given as to what should be included, no detail is given as to how much detail or at what level these subjects should be taught. Subsequently, approved institutions are responsible for their own course content. This has resulted in inconsistent and varied approaches to integrating the sciences in undergraduate nursing curricula. Following a recent review of the undergraduate nursing curriculum in one university in the Republic of Ireland a decision was made to combine the teaching, learning and assessment of Applied Psychology with Interpersonal Communication skills. This paper will describe the developmental process and evaluation of the integrated module. Copyright © 2014 Elsevier Ltd. All rights reserved.

[Research Misconduct in Japan and How It Is Covered by the Media].

PubMed

Enoki, Eisuke

2018-01-01

　Cases of research misconduct (fabrication, falsification, and plagiarism) have been increasing worldwide, including in Japan. In particular, since 2006, many cases of research misconduct have been reported in Japan, and these cases have also been covered by the media. The 2014 case of the withdrawal of articles on STAP cells followed a rare course in which research misconduct became a full-blown social phenomenon. In recent years, even the University of Tokyo has experienced reported cases of research misconduct. In this report, I would like to introduce some representative cases of research misconduct in the field of life sciences over the past decade. These examples include studies conducted at Osaka University Graduate School of Medicine (2006), Osaka University Graduate School of Frontier Bioscience (2006), Ryukyu University School of Medicine (2010), Toho University School of Medicine (2012), The University of Tokyo Institute of Molecular and Cellular Biosciences (2013), and several cases outside of Japan. I will discuss what researchers should do to reduce the incidence of research misconduct. In addition, I will discuss how these cases were covered by the media, because the public's impression of research misconduct is formed by media coverage.

Y-12 Site environmental protection program implementation plan (EPPIP)

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-11-01

The Y-12 Plant Environmental Protection Program is conducted to: (1) protect public health and the environment from chemical and radiological releases occurring from current plant operations and past waste management and operational practices; (2) ensure compliance with federal, state, and local environmental regulations and DOE directives; (3) identify potential environmental problems; (4) evaluate existing environmental contamination and determine the need for remedial actions and mitigative measures; (5) monitor the progress of ongoing remedial actions and cleanup measures; and (6) inform the public of environmental issues relating to DOE operations. DOE Order 5400.1, General Environmental Protection Program, defines the general requirementsmore » for environmental protection programs at DOE facilities. This Environmental Protection Program Implementation Plan (EPPIP) defines the methods by which the Y-12 Plant staff will comply with the order by: (1) referencing environmental protection goals and objectives and identifying strategies and timetables for attaining them; (2) providing the overall framework for the design and implementation of the Y-12 Environmental Protection Program; and (3) assigning responsibilities for complying with the requirements of the order. The EPPIP is revised and updated annually.« less

25 CFR 170.450 - What archeological and environmental requirements must the IRR Program meet?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false What archeological and environmental requirements must... Reservation Roads Program Facilities Environmental and Archeological Requirements § 170.450 What archeological and environmental requirements must the IRR Program meet? (a) The archeological and environmental...

Environmental Epidemiology Program

Science.gov Websites

accessible with JavaScript activated. Utah Department of Health Bureau of Epidemiology Environmental Epidemiology Program (EEP) The Environmental Epidemiology Program strives to improve the health of Utah residents through science-based environmental health policy and by empowering citizens with knowledge about

Environmental Technician Training in the United Kingdom.

ERIC Educational Resources Information Center

Potter, John F.

1985-01-01

Stresses the need for qualified environmental science technicians and for training courses in this area. Provides program information and statistical summarization of a national diploma program for environmental technicians titled "Business and Technician Education Council." Reviews the program areas of environmental analysis and…

Molecular cell biology and advanced microscopy: an interview with Joshua Z. Rappoport.

PubMed

Rappoport, Joshua Z

2018-05-01

Dr Joshua Z Rappoport, PhD, speaks to Nawsheen Boodhun, Managing Editor. Rappoport completed his bachelor's degree in Biology at Brown University (RI, USA). He then went on to earn a PhD from the Program in Mechanisms of Disease and Therapeutics at the Mount Sinai School of Medicine Graduate School of Biological Sciences of New York University (USA). Rappoport spent the early parts of his career working as a postdoctoral researcher at the Laboratory of Cellular Biophysics based in The Rockefeller University (NY, USA). He was subsequently recruited as a tenured faculty member to work as part of the School of Biosciences at the University of Birmingham (UK). 2014 marked the return of Rappoport to the USA, where he is currently a Research Professor in Molecular Cell Biology at the Northwestern University Feinberg School of Medicine (IL, USA). He is also the Director of the Center for Advanced Microscopy (CAM) and Nikon Imaging Center (NIC), a large core facility consisting of eight members of staff that support around 200 different laboratories.

Status of Charge Exchange Cross Section Measurements for Highly Charged Ions on Atomic Hydrogen

NASA Astrophysics Data System (ADS)

Draganic, I. N.; Havener, C. C.; Schultz, D. R.; Seely, D. G.; Schultz, P. C.

2011-05-01

Total cross sections of charge exchange (CX) for C5+, N6+, and O7+ ions on ground state atomic hydrogen are measured in an extended collision energy range of 1 - 20,000 eV/u. Absolute CX measurements are performed using an improved merged-beams technique with intense highly charged ion beams extracted from a 14.5 GHz ECR ion source mounted on a high voltage platform. In order to improve the problematic H+ signal collection for these exoergic CX collisions at low relative energies, a new double focusing electrostatic analyzer was installed. Experimental CX data are in good agreement with all previous H-oven relative measurements at higher collision energies. We compare our results with the most recent molecular orbital close-coupling (MOCC) and atomic orbital close-coupling (AOCC) theoretical calculations. Work supported by the NASA Solar & Heliospheric Physics Program NNH07ZDA001N, the Office of Fusion Energy Sciences and the Division of Chemical Sciences, Geosciences, and Biosciences, and the Office of Basic Energy Sciences of the U.S. DoE.

Draft Genome Sequence of the Phytopathogenic Fungus Ganoderma boninense, the Causal Agent of Basal Stem Rot Disease on Oil Palm

PubMed Central

Tanjung, Zulfikar Achmad; Aditama, Redi; Buana, Rika Fithri Nurani; Pratomo, Antonius Dony Madu; Tryono, Reno; Liwang, Tony

2018-01-01

ABSTRACT Ganoderma boninense is the dominant fungal pathogen of basal stem rot (BSR) disease on Elaeis guineensis. We sequenced the nuclear genome of mycelia using both Illumina and Pacific Biosciences platforms for assembly of scaffolds. The draft genome comprised 79.24 Mb, 495 scaffolds, and 26,226 predicted coding sequences. PMID:29700132

Do Frogs Still Get Their Kicks On Route 66? A Transcontinental Transect For Amphibian Chytrid Fungus (Batrachochytrium Dendrobatidis) Infection On U.S. Department Of Defense Installations

DTIC Science & Technology

2011-01-04

Collins JP (2006) Emerging infectious disease and the loss of biodiversity in a Neotropical amphibian community. Ecology 103: 3165-3170. Lips KR...and Other Federal Lands in Sustaining Biodiversity . BioScience 58: 339-347. Stuart SN, Chanson JS, Cox NA, Young BE, Rodrigues ASL, Fischman DL

The Role Biomedical Science Laboratories Can Play in Improving Science Knowledge and Promoting First-Year Nursing Academic Success

ERIC Educational Resources Information Center

Arneson, Pam

2011-01-01

The need for additional nursing and health care professionals is expected to increase dramatically over the next 20 years. With this in mind, students must have strong biomedical science knowledge to be competent in their field. Some studies have shown that participation in bioscience laboratories can enhance science knowledge. If this is true, an…

Nanocrystalline Anatase Titania Supported Vanadia Catalysts: Facet-dependent Structure of Vanadia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Wei-Zhen; Gao, Feng; Li, Yan

2015-07-09

Titania supported vanadia, a classic heterogeneous catalyst for redox reactions, typically has nonhomogeneous vanadia species on various titania facets, making it challenging not only to determine and quantify each species but also to decouple their catalytic contributions. We prepared truncated tetragonal bipyramidal (TiO2-TTB) and rod-like (TiO2-Rod) anatase titania with only {101} and {001} facets at ratios of about 80:20 and 93:7, respectively, and used them as supports of sub-monolayer vanadia. The structure and redox properties of supported vanadia were determined by XRD, TEM, XPS, EPR, Raman, FTIR and TPR, etc. It was found that vanadia preferentially occupy TiO2 {001} facetsmore » and form isolated O=V4+(O-Ti)2 species, and with further increase in vanadia surface coverage, isolated O=V5+(O-Ti)3 and oligomerized O=V5+(O-M)3 (M = Ti or V) species form on TiO2 {101} facets. The discovery on support facet-dependent structure of vanadia on anatase titania is expected to enable the elucidation of structure-function correlations on high surface area TiO2 supported vanadia catalysts. This work was supported by U. S. Department of Energy (DOE), Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Biosciences and Geosciences. The research was performed in the Environmental Molecular Sciences Laboratory (EMSL), a national scientific user facility sponsored by the DOE Office of Biological and Environmental Research, and located at Pacific Northwest National Laboratory (PNNL). PNNL is operated for DOE by Battelle.« less

Mechanistic insights into aqueous phase propanol dehydration in H-ZSM-5 zeolite

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mei, Donghai; Lercher, Johannes A.

Aqueous phase dehydration of 1-propanol over H-ZSM-5 zeolite was investigated using density functional theory (DFT) calculations. The water molecules in the zeolite pores prefer to aggregate via the hydrogen bonding network and be protonated at the Brønsted acidic sites (BAS). Two typical configurations, i.e., dispersed and clustered, of water molecules were identified by ab initio molecular dynamics simulation of the mimicking aqueous phase H-ZSM-5 zeolite unit cell with 20 water molecules per unit cell. DFT calculated Gibbs free energies suggest that the dimeric propanol-propanol, the propanol-water complex, and the trimeric propanol-propanol-water are formed at high propanol concentrations, which provide amore » kinetically feasible dehydration reaction channel of 1-propanol to propene. However, calculation results also indicate that the propanol dehydration via the unimolecular mechanism becomes kinetically discouraged due to the enhanced stability of the protonated dimeric propanol and the protonated water cluster acting as the BAS site for alcohol dehydration reaction. This work was supported by the US Department of Energy (DOE), Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences & Biosciences. Pacific Northwest National Laboratory (PNNL) is a multiprogram national laboratory operated for DOE by Battelle. Computing time was granted by the grand challenge of computational catalysis of the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL). EMSL is a national scientific user facility located at Pacific Northwest National Laboratory (PNNL) and sponsored by DOE’s Office of Biological and Environmental Research.« less

Dehydration of 1-octadecanol over H-BEA: A combined experimental and computational study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Song, Wenji; Liu, Yuanshuai; Barath, Eszter

Liquid phase dehydration of 1-octdecanol, which is intermediately formed during the hydrodeoxygenation of microalgae oil, has been explored in a combined experimental and computational study. The alkyl chain of C18 alcohol interacts with acid sites during diffusion inside the zeolite pores, resulting in an inefficient utilization of the Brønsted acid sites for samples with high acid site concentrations. The parallel intra- and inter- molecular dehydration pathways having different activation energies pass through alternative reaction intermediates. Formation of surface-bound alkoxide species is the rate-limiting step during intramolecular dehydration, whereas intermolecular dehydration proceeds via a bulky dimer intermediate. Octadecene is the primarymore » dehydration product over H-BEA at 533 K. Despite of the main contribution of Brønsted acid sites towards both dehydration pathways, Lewis acid sites are also active in the formation of dioctadecyl ether. The intramolecular dehydration to octadecene and cleavage of the intermediately formed ether, however, require strong BAS. L. Wang, D. Mei and J. A. Lercher, acknowledge the partial support from the US Department of Energy, Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences & Biosciences. Pacific Northwest National Laboratory (PNNL) is a multiprogram national laboratory operated for DOE by Battelle. Computing time was granted by the grand challenge of computational catalysis of the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) and by the National Energy Research Scientific Computing Center (NERSC). EMSL is a national scientific user facility located at Pacific Northwest National Laboratory (PNNL) and sponsored by DOE’s Office of Biological and Environmental Research.« less

Determinants of Risk Infection During Therapy with Anti TNF-Alpha Blocking Agents in Rheumatoid Arthritis

PubMed Central

Benucci, M; Saviola, G; Baiardi, P; Manfredi, M; Sarzi Puttini, P; Atzeni, Fabiola

2012-01-01

The use of TNF-alpha antagonists (infliximab, etanercept, adalimumab) has changed the course of many rheumatic diseases including rheumatoid arthritis (RA). Since their approval, some questions regarding their safety including infections have been observed. The aim of the study was to evaluate the changes in cytokines levels and cells subsets in patients with RA during anti TNF blocking agents treatment and the possible effect on infections’ development. We evaluated in 89 RA patients [39 treated with etanercept (ETN), 29 with adalimumab (ADA) and 21 with infliximab (IFN)] at baseline and after 6 months the following parameters: procalcitonin, ESR, CRP, cytokines as TNF, IL-6, IL-10, IL-8 and the TNF/IL-10 ratio, and peripheral mononuclear cells as CD3+, CD3+/CD4+, CD3+/CD8+, CD19+, CD3- /CD16+/56+, CD14+HLADR+, CD20+, CD19+/CD38+. Peripheral mononuclear cells were detected by flow cytometric system Cytomics FC500 and cytokines circulating levels by a quantitative sandwich enzyme immunoassay technique (Human IL-8 Instant ELISAe Bioscience, Human IL-6 Instant ELISA e Bioscience, Human IL-10 Instant ELISAe Bioscience and Human TNF-a Quantikine immunoassay RD system). A lower reduction of CD14+HLADR+ in ADA group 54.6±10.4% vs ETA 48.4±15.7% vs INF 40.7±16.5%, p<0.039 was found. No differences in all three groups on peripheral mononuclear cells CD3+, CD3+/CD4+, CD3+/CD8+, CD19+, CD 20+, CD19+/CD38+, CD3-/CD16+/56+, and cytokine circulating levels were found. The number of infections at 6 months was: 10.3% in ADA group, 12.8% in ETN group and 19.04% in IFN group. A correlation was found between the reduction in CD14+HLADR+ cells and IFN treatment. Our data showed that the level of CD14+HLADR+ cells was reduced during therapy with IFN. ADA and ETN don’t reduce lymphocyte populations and their subsets such as CD14+HLADR+ cells that play an important role host defence. PMID:22655000

Environmental Identity: A New Approach to Understanding Students' Participation in Environmental Learning Programs

ERIC Educational Resources Information Center

Jaksha, Amanda P.

2013-01-01

The goal of this study is to develop an understanding of how participants express their environmental identities during an environmental learning program. Past research on the outcomes of environmental learning programs has focused primarily on changes in knowledge and attitudes. However, even if knowledge or attitudes can be accurately measured,…

40 CFR 52.1110 - Small business stationary source technical and environmental compliance assistance program.

Code of Federal Regulations, 2010 CFR

2010-07-01

... technical and environmental compliance assistance program. 52.1110 Section 52.1110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Maryland § 52.1110 Small business stationary source technical and environmental...

ENVIRONMENTAL TECHNOLOGY VERIFICATION PROGRAM: QUALITY AND MANAGEMENT PLAN FOR THE PILOT PERIOD (1995-2000)

EPA Science Inventory

Based upon the structure and specifications in ANSI/ASQC E4-1994, Specifications and Guidelines for Quality Systems for Environmental Data Collection and Environmental Technology Programs, the Environmental Technology Verification (ETV) program Quality and Management Plan (QMP) f...

An Environmental Education Program (K-12), Based on Environmental Encounters

ERIC Educational Resources Information Center

Stapp, William B.

1971-01-01

Describes a strategy for development and implementation of a comprehensive environmental education program (K-12) which can be integrated into existing curriculum of a school. Environmental encounters" stressed as meaningful approaches to goal achievement. Philosophy of spaceship earth" is fundamental to the program. (LK)

Evaluation of Environmental Education in Schools.

ERIC Educational Resources Information Center

Connect, 1984

1984-01-01

This newsletter discusses the evaluation of environmental education (EE) in schools, highlighting an introductory chapter of a proposed Unesco-United Nations environmental program guide on evaluating such programs. The benefits of evaluating an EE program (including program improvement, growth in student learning, better environment, and program…

Environmental Technology.

ERIC Educational Resources Information Center

Columbus State Community Coll., OH.

This document contains materials developed for and about the environmental technology tech prep program of the South-Western City Schools in Ohio. Part 1 begins with a map of the program, which begins with an environmental science technology program in grades 11 and 12 that leads to entry-level employment or a 2-year environmental technology…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larsen, Barbara L.

The annual program report provides detailed information about all aspects of the SNL/CA Environmental Planning and Ecology Program for a given calendar year. It functions as supporting documentation to the SNL/CA Environmental Management System Program Manual. The 2005 program report describes the activities undertaken during the past year, and activities planned in future years to implement the Planning and Ecology Program, one of six programs that supports environmental management at SNL/CA.

Resource Programs : Draft Environmental Impact Statement, Volume 2, Appendices.

DOE Office of Scientific and Technical Information (OSTI.GOV)

United States. Bonneville Power Administration.

1992-03-01

Every two years, Bonneville Power Administration (BPA) prepares a Resource Program which identifies the resource actions BPA will take to meet its obligation to serve the forecasted power requirements of its customers. The Resource Program`s Environmental Impact Statement (RPEIS) is a programmatic environmental document which will support decisions made in several future Resource Programs. Environmental documents tiered to the EIS may be prepared on a site-specific basis. The RPEIS includes a description of the environmental effects and mitigation for the various resource types available in order to evaluate the trade-offs among them. It also assesses the environmental impacts of addingmore » thirteen alternative combinations of resources to the existing power system. This report contains the appendices to the RPEIS.« less

Environmental regulations: Technical reference manual TRM 016.01, September 15, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-09-15

This TRM is divided into two primary sections. The first section entitled Environmental Programs provides a synopsis of each environmental Act (Federal Law). The second section of the TRM is entitled Environmental Operations. This section is in effect the nuts and bolts of the regulatory compliance programs. In this section, the program manager can reference specific requirements which will aid in structuring the compliance program.

Environmental Management Science Program Workshop. Proceedings

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1998-07-01

The Department of Energy Office of Environmental Management (EM), in partnership with the Office of Energy Research (ER), designed, developed, and implemented the Environmental Management Science Program as a basic research effort to fund the scientific and engineering understanding required to solve the most challenging technical problems facing the government's largest, most complex environmental cleanup program. The intent of the Environmental Management Science Program is to: (1) Provide scientific knowledge that will revolutionize technologies and cleanup approaches to significantly reduce future costs, schedules, and risks. (2) Bridge the gap between broad fundamental research that has wide-ranging applications such as thatmore » performed in the Department's Office of Energy Research and needs-driven applied technology development that is conducted in Environmental Management's Office of Science and Technology. (3) Focus the nation's science infrastructure on critical Department of Energy environmental problems. In an effort to share information regarding basic research efforts being funded by the Environmental Management Science Program and the Environmental Management/Energy Research Pilot Collaborative Research Program (Wolf-Broido Program), this CD includes summaries for each project. These project summaries, available in portable document format (PDF), were prepared in the spring of 1998 by the principal investigators and provide information about their most recent project activities and accomplishments.« less

The effectiveness of environmental education programs from the perspectives of three stakeholders: Participants, sponsors, and professionals

NASA Astrophysics Data System (ADS)

Luera, Gail Rose

As the field of environmental education has matured since its inception in 1970, so have the number and variety of environmental programs. Along with the increased number of programs has come a need for in-depth program evaluations. This is especially critical because of reductions in educational funding and competition for a place in an already crowded curriculum. Evaluation is essential to convince the educational community that environmental education can improve the curriculum, ensure cost effectiveness, and become more relevant to students. Drawing on program evaluation research, action research, and interpretive (qualitative) research to strengthen the research design and methodology, this dissertation explores how different stakeholders of two environmental education programs determine program effectiveness. Effectiveness was investigated primarily through the use of in-depth interviews of participants, program sponsors, and professionals. Program success at the professional field level was determined by criteria set by the North American Association for Environmental Education. Characteristics considered in the selection of programs for this study included: method of dissemination, sponsor, subject focus, the method of action which they encourage, and their vision for the future. Using the qualitative case study approach, the Orange County Outdoor Science School in California and Project WILD in Michigan were evaluated. The results show that all levels of stakeholders perceived the two programs to be effective. Areas of effectiveness varied with each program and by stakeholder level. Issues facing each program also differed. At the Orange County Outdoor Science School, program cost was named as the major issue. The most often cited issues for Project WILD was public awareness of the program and stabilizing long term financial support for the Michigan program. Interview data were analyzed at the question level in addition to the thematic level. Themes which emerged from the interview responses included cost of the program, respondent and program receptivity to change, reconciling program philosophy with personal philosophy (Orange County program), perception of environmental education, definition of the program's boundaries and barriers to implementation (Project WILD). The dissertation concludes with a presentation of a preliminary model for environmental education program evaluation and recommendations for future related research.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larsen, Barbara L.

The annual program report provides detailed information about all aspects of the Sandia National Laboratories, California (SNL/CA) Environmental Planning and Ecology Program for a given calendar year. It functions as supporting documentation to the SNL/CA Environmental Management System Program Manual. The 2006 program report describes the activities undertaken during the past year, and activities planned in future years to implement the Planning and Ecology Program, one of six programs that supports environmental management at SNL/CA.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larsen, Barbara L.

The annual program report provides detailed information about all aspects of the Sandia National Laboratories, California (SNL/CA) Environmental Planning and Ecology Program for a given calendar year. It functions as supporting documentation to the SNL/CA Environmental Management System Program Manual. The program report describes the activities undertaken during the past year, and activities planned in future years to implement the Planning and Ecology Program, one of six programs that supports environmental management at SNL/CA.

International Environmental Education: General Perspectives, Communications, and Program Status in Selected Countries.

ERIC Educational Resources Information Center

Shaffer, Barry E.

To enlighten the reader on the status of environmental education internationally, this paper discusses current environmental concerns, trends, and problems; reviews environmental-related communications between countries since 1965; and describes environmental education programs in selected countries. Environmental education is interpreted to…

Inhibition of Prostate Cancer Skeletal Metastases by Targeting Cathepsin K

DTIC Science & Technology

2009-05-01

micro synthetic calcium phosphate thin films coated onto the culture vessels. As a parallel study, a 96-well plate which contained dentin slice...bone resorption in vitro. (A) Representative images of resorption pits on dentin slices or synthetic calcium phosphate thin films are shown. Left...Osteologic Bone cell culture system (BD Bioscience) that consist of sub-micro synthetic calcium phosphate thin films coated on to the culture vessels and

Biochemical Characterisation of TSC1 and TSC2 Variants Identifiedd in Patients with Tuberous sclerosis Complex

DTIC Science & Technology

2008-07-01

near infrared fluorophores in combination with an infrared scanner enabling two distinct antibody signals to be detected simultaneously and quantified...foetal calf serum. Twenty-four hours after transfection, the cells were harvested and analysed by immunoblotting as before or by near infrared ...determined by immunoblotting as before except that the blots were developed using Odyssey near infrared detection (Li-Cor Biosciences). Cells expressing

Algae-Derived Dietary Ingredients Nourish Animals

NASA Technical Reports Server (NTRS)

2015-01-01

In the 1980s, Columbia, Maryland-based Martek Biosciences Corporation worked with Ames Research Center to pioneer the use of microalgae as a source of essential omega-3 fatty acids, work that led the company to develop its highly successful Formulaid product. Now the Nutritional Products Division of Royal DSM, the company also manufactures DHAgold, a nutritional supplement for pets, livestock and farm-raised fish that uses algae to deliver docosahexaenoic acid (DHA).

Draft Genome Sequence of the Phytopathogenic Fungus Ganoderma boninense, the Causal Agent of Basal Stem Rot Disease on Oil Palm.

PubMed

Utomo, Condro; Tanjung, Zulfikar Achmad; Aditama, Redi; Buana, Rika Fithri Nurani; Pratomo, Antonius Dony Madu; Tryono, Reno; Liwang, Tony

2018-04-26

Ganoderma boninense is the dominant fungal pathogen of basal stem rot (BSR) disease on Elaeis guineensis We sequenced the nuclear genome of mycelia using both Illumina and Pacific Biosciences platforms for assembly of scaffolds. The draft genome comprised 79.24 Mb, 495 scaffolds, and 26,226 predicted coding sequences. Copyright © 2018 Utomo et al.

Gene-enriched draft genome of the cattle tick Rhipicephalus microplus: Assembly by the hybrid Pacific Biosciences/Illumina approach enabled analysis of the highly repetitive genome

USDA-ARS?s Scientific Manuscript database

The genome of the cattle tick R. microplus, an ectoparasite with global distribution, is estimated to be 7.1 Gbp and consists of ~70% repetitive DNA. We report the first assembly of a tick genome that utilized a hybrid sequencing and assembly approach to capture the repetitive fractions of the genom...

Omics Integration in Biology and Medicine Workshop | Office of Cancer Clinical Proteomics Research

Cancer.gov

The focus of this meeting will be on the emerging field of integrating disparate omic data from genomics, proteomics, glycomics, etc. in order to better understand key biological processes and also improve clinical practice. Discussants will focus on identifying the technical and biological barriers in omic integration, with solutions to build a consensus towards data integration in bioscience and to better define phenotypes.

Toxicologic and Analytical Studies with T-2 and Related Trichothecene Mycotoxins

DTIC Science & Technology

1984-09-01

SUPPORTED BY U. S. ARMY MEDICAL RESEARCH AND DEVELOPMENT COMMAND Fort Detrick, Frederick, Maryland 21701 Contract No. DAMV 17-82-C-2179 College of...Paula M. Bratich, Researcher Robert H. Poppenga, Researcher Richard A. Corley, Researcher "SUBMITTED SEPTEMBER 4, 1984 SUPPORTED BY’ U. S. ARMY MEDICAL ... Medical Records Technician Technical Reports ,7V Toxicology Department of Vet Biosciences Walter E. Hoffmann Associate Professor of Clinical

1996 LMITCO environmental monitoring program report for the Idaho National Engineering and Environmental Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-09-01

This report describes the calendar year 1996 environmental surveillance and compliance monitoring activities of the Lockheed Martin Idaho Technologies Company Environmental Monitoring Program performed at the Idaho National Engineering and Environmental Laboratory (INEEL). Results of sampling performed by the Radiological Environmental Surveillance, Site Environmental Surveillance, Drinking Water, Effluent Monitoring, Storm Water Monitoring, Groundwater Monitoring, and Special Request Monitoring Programs are included in this report. The primary purposes of the surveillance and monitoring activities are to evaluate environmental conditions, to provide and interpret data, to verify compliance with applicable regulations or standards, and to ensure protection of human health and themore » environment. This report compares 1996 data with program-specific regulatory guidelines and past data to evaluate trends.« less

Strategies for Evaluating Complex Environmental Education Programs

NASA Astrophysics Data System (ADS)

Williams, V.

2011-12-01

Evidence for the effectiveness of environmental education programs has been difficult to establish for many reasons. Chief among them are the lack of clear program objectives and an inability to conceptualize how environmental education programs work. Both can lead to evaluations that make claims that are difficult to substantiate, such as significant changes in student achievement levels or behavioral changes based on acquisition of knowledge. Many of these challenges can be addressed by establishing the program theory and developing a logic model. However, claims of impact on larger societal outcomes are difficult to attribute solely to program activities. Contribution analysis may offer a promising method for addressing this challenge. Rather than attempt to definitively and causally link a program's activities to desired results, contribution analysis seeks to provide plausible evidence that can reduce uncertainty regarding the 'difference' a program is making to observed outcomes. It sets out to verify the theory of change behind a program and, at the same time, takes into consideration other influencing factors. Contribution analysis is useful in situations where the program is not experimental-there is little or no scope for varying how the program is implemented-and the program has been funded on the basis of a theory of change. In this paper, the author reviews the feasibility of using contribution analysis as a way of evaluating the impact of the GLOBE program, an environmental science and education program. Initially conceptualized by Al Gore in 1995, the program's implementation model is based on worldwide environmental monitoring by students and scientists around the globe. This paper will make a significant and timely contribution to the field of evaluation, and specifically environmental education evaluation by examining the usefulness of this analysis for developing evidence to assess the impact of environmental education programs.

INEL Geothermal Environmental Program. Final environmental report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thurow, T.L.; Cahn, L.S.

1982-09-01

An overview of environmental monitoring programs and research during development of a moderate temperature geothermal resource in the Raft River Valley is presented. One of the major objectives was to develop programs for environmental assessment and protection that could serve as an example for similar types of development. The monitoring studies were designed to establish baseline conditions (predevelopment) of the physical, biological, and human environment. Potential changes were assessed and adverse environmental impacts minimized. No major environmental impacts resulted from development of the Raft River Geothermal Research Facility. The results of the physical, biological, and human environment monitoring programs aremore » summarized.« less

A quantitative and qualitative inquiry of the impact of a residential environmental education program on student learning

NASA Astrophysics Data System (ADS)

Oberst, Mary Claire

Quantitative and qualitative research methods were utilized in a two-phase design approach to describe the impact of a residential environmental education program on student learning and provide a profile of program participants. In phase one, within a nonequivalent pre-posttest control group design, fourth and fifth-grade students (N = 490) were administered learner-outcome-based instruments in terms of ecological knowledge and environmental attitude. The treatment group consisted of students who participated in the 4-6th grade level curriculum of the residential environmental education program at Cuyahoga Valley Environmental Education Center. A teacher survey was implemented to provide a profile of the teachers participating in the residential program with their students. Major findings indicate a statistically significant impact on student ecological knowledge (p ≤.05); no statistically significant impact on environmental attitude was found. Data collected from the teacher survey provided a profile of the contact teachers who participated in the study. Eighty-eight percent of these primarily fourth and fifth grade teachers teach science. The majority have a Master's Degree and all have had some coursework related to environmental education. Ninety-two percent have attended at least one workshop related to environmental education and seventy-five percent have attended up to five environmental education related workshops within the last five years. All of these teachers use environmental education techniques and content in the classroom and all report a high level of environmental concern. In the second phase of the study, a purposeful sample of students, teachers, and parents was interviewed; data were collected through program observation, interviews, and program document collection. Content analysis yielded the following patterns in regard to student, teacher, and parent perceptions of what students learned: (1) natural history; (2) environmental awareness; (3) environmental ethics; and environmental action. These patterns were consistent with overall program goals. This research has revealed curriculum impact on student learning. In terms of the quantity of student learning, findings indicate a statistically significant gain in student ecological knowledge. In terms of a portrait of student learning, the four patterns that emerged from the qualitative data revealed program impact associated with program goals as well as goals for environmental education.

Taking nanomedicine teaching into practice with atomic force microscopy and force spectroscopy.

PubMed

Carvalho, Filomena A; Freitas, Teresa; Santos, Nuno C

2015-12-01

Atomic force microscopy (AFM) is a useful and powerful tool to study molecular interactions applied to nanomedicine. The aim of the present study was to implement a hands-on atomic AFM course for graduated biosciences and medical students. The course comprises two distinct practical sessions, where students get in touch with the use of an atomic force microscope by performing AFM scanning images of human blood cells and force spectroscopy measurements of the fibrinogen-platelet interaction. Since the beginning of this course, in 2008, the overall rating by the students was 4.7 (out of 5), meaning a good to excellent evaluation. Students were very enthusiastic and produced high-quality AFM images and force spectroscopy data. The implementation of the hands-on AFM course was a success, giving to the students the opportunity of contact with a technique that has a wide variety of applications on the nanomedicine field. In the near future, nanomedicine will have remarkable implications in medicine regarding the definition, diagnosis, and treatment of different diseases. AFM enables students to observe single molecule interactions, enabling the understanding of molecular mechanisms of different physiological and pathological processes at the nanoscale level. Therefore, the introduction of nanomedicine courses in bioscience and medical school curricula is essential. Copyright © 2015 The American Physiological Society.

Diversity of the TLR4 Immunity Receptor in Czech Native Cattle Breeds Revealed Using the Pacific Biosciences Sequencing Platform.

PubMed

Novák, Karel; Pikousová, Jitka; Czerneková, Vladimíra; Mátlová, Věra

2017-07-03

The allelic variants of immunity genes in historical breeds likely reflect local infection pressure and therefore represent a reservoir for breeding. Screening to determine the diversity of the Toll-like receptor gene TLR4 was conducted in two conserved cattle breeds: Czech Red and Czech Red Pied. High-throughput sequencing of pooled PCR amplicons using the PacBio platform revealed polymorphisms, which were subsequently confirmed via genotyping techniques. Eight SNPs found in coding and adjacent regions were grouped into 18 haplotypes, representing a significant portion of the known diversity in the global breed panel and presumably exceeding diversity in production populations. Notably, the ancient Czech Red breed appeared to possess greater haplotype diversity than the Czech Red Pied breed, a Simmental variant, although the haplotype frequencies might have been distorted by significant crossbreeding and bottlenecks in the history of Czech Red cattle. The differences in haplotype frequencies validated the phenotypic distinctness of the local breeds. Due to the availability of Czech Red Pied production herds, the effect of intensive breeding on TLR diversity can be evaluated in this model. The advantages of the Pacific Biosciences technology for the resequencing of long PCR fragments with subsequent direct phasing were independently validated.

Navigating Bioethical Waters: Two Pilot Projects in Problem-Based Learning for Future Bioscience and Biotechnology Professionals.

PubMed

Berry, Roberta M; Levine, Aaron D; Kirkman, Robert; Blake, Laura Palucki; Drake, Matthew

2016-12-01

We believe that the professional responsibility of bioscience and biotechnology professionals includes a social responsibility to contribute to the resolution of ethically fraught policy problems generated by their work. It follows that educators have a professional responsibility to prepare future professionals to discharge this responsibility. This essay discusses two pilot projects in ethics pedagogy focused on particularly challenging policy problems, which we call "fractious problems". The projects aimed to advance future professionals' acquisition of "fractious problem navigational" skills, a set of skills designed to enable broad and deep understanding of fractious problems and the design of good policy resolutions for them. A secondary objective was to enhance future professionals' motivation to apply these skills to help their communities resolve these problems. The projects employed "problem based learning" courses to advance these learning objectives. A new assessment instrument, "Skills for Science/Engineering Ethics Test" (SkillSET), was designed and administered to measure the success of the courses in doing so. This essay first discusses the rationale for the pilot projects, and then describes the design of the pilot courses and presents the results of our assessment using SkillSET in the first pilot project and the revised SkillSET 2.0 in the second pilot project. The essay concludes with discussion of observations and results.

Mapping the yeast host cell response to recombinant membrane protein production: relieving the biological bottlenecks.

PubMed

Ashe, Mark P; Bill, Roslyn M

2011-06-01

Understanding the structures and functions of membrane proteins is an active area of research within bioscience. Membrane proteins are key players in essential cellular processes such as the uptake of nutrients, the export of waste products, and the way in which cells communicate with their environment. It is therefore not surprising that membrane proteins are targeted by over half of all prescription drugs. Since most membrane proteins are not abundant in their native membranes, it is necessary to produce them in recombinant host cells to enable further structural and functional studies. Unfortunately, achieving the required yields of functional recombinant membrane proteins is still a bottleneck in contemporary bioscience. This has highlighted the need for defined and rational optimization strategies based upon experimental observation rather than relying on trial and error. We have published a transcriptome and subsequent genetic analysis that has identified genes implicated in high-yielding yeast cells. These results have highlighted a role for alterations to a cell's protein synthetic capacity in the production of high yields of recombinant membrane protein: paradoxically, reduced protein synthesis favors higher yields. These results highlight a potential bottleneck at the protein folding or translocation stage of protein production. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Does the transition to an active-learning environment for the introductory course reduce students' overall knowledge of the various disciplines in biology?

PubMed

Simurda, Maryanne C

2012-01-01

As biology education is being redesigned toward an interdisciplinary focus and as pedagogical trends move toward active-learning strategies and investigative experiences, a restructuring of the course content for the Introductory Biology course is necessary. The introductory course in biology has typically been a survey of all the biosciences. If the total number of topics covered is reduced, is the students' overall knowledge of biology also reduced? Our introductory course has been substantially modified away from surveying the biological sciences and toward providing a deep understanding of a particular biological topic, as well as focusing on developing students' analytical and communication skills. Because of this shift to a topic-driven approach for the introductory course, we were interested in assessing our graduating students' overall knowledge of the various biological disciplines. Using the Major Field Test - Biology (Educational Testing Service (ETS), Princeton, NJ), we compared the test performance of graduating students who had a traditional lecture-based introductory course to those who had a topic-driven active-learning introductory course. Our results suggest that eliminating the traditional survey of biology and, instead, focusing on quantitative and writing skills at the introductory level do not affect our graduating students' overall breadth of knowledge of the various biosciences.

40 CFR 147.2300 - State-administered program.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Water Resources and Environmental Engineering, Chapter 13 Water Pollution Control Regulations... Section 147.2300 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS... those wells on Indian lands, is the program administered by the Vermont Department of Environmental...

Integrated environmental planning in the Philippines: A case study of the Palawan Integrated Environmental Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ganapin, D.J. Jr.

1987-01-01

Integrated environmental planning was analyzed using the case of the Palawan Integrated Environmental Program in the Philippines. The study explores the relationship between development and environmental planning and evaluates the importance of organizational coordination and timing in the integration of these two concerns. Factors affecting the accomplishment of the objectives of integrated environmental planning were also studied. Two planning phases of the Palawan Integrated Environmental Program were observed using the case study approach. Observations of various planning participants-consultants, middle level agency personnel, heads of local agencies-were also considered. The integration of environmental considerations in development planning was found to bemore » beneficial to both environmental and development concerns. The experience showed that such integration requiring tight organizational coordination and the proper timing of activities and outputs. The success of the Palawan Integrated Environmental Program was also found to depend on effective communication, the political functionality of the government, the leadership of its executives, the presence of appropriate structures of authority, sufficiency of funds and manpower and the availability of appropriate environmental planning techniques. Recommendations are provided to further strengthen the integration of environmental considerations in development planning and increase the effectiveness of integrated environmental programs.« less

Environmental Quality Research and Development. A Review and Analysis of Federal Programs.

ERIC Educational Resources Information Center

Executive Office of the President, Washington, DC.

This is the first interagency report on Federal environmental quality research and development programs that presents program descriptions, levels of funding, and analyses. Undertaken at the request of the Federal Council for Science and Technology, the study may be useful in identifying environmental quality research and development programs in…

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY'S ENVIRONMENTAL INDICATORS INITIATIVE AND BIOMARKERS DATABASE

EPA Science Inventory

Within the United States Environmental Protection Agency (USEPA), there are several on-going programs and projects that collect health and environmental information. The USEPA's Environmental Indicators Initiative is one such program which includes the development of environmenta...

Environmental Horticulture Program Guide.

ERIC Educational Resources Information Center

Georgia Univ., Athens. Dept. of Vocational Education.

This program guide contains the standard environmental horticulture curriculum for technical institutes in Georgia. The curriculum encompasses the minimum competencies required for entry-level workers in the environmental horticulture field. The general information section contains the following: purpose and objectives; program description,…

ENVIRONMENTAL TECHNOLOGY VERIFICATION (ETV) PROGRAM CASE STUDIES: DEMONSTRATING PROGRAM OUTCOMES

EPA Science Inventory

The U.S. Environmental Protection Agency (EPA) Environmental Technology Verification (ETV) Program evaluates the performance of innovative air, water, pollution prevention and monitoring technologies that have the potential to improve human health and the environment. This bookle...

Review of the FY15 Defense Environmental International Cooperation (DEIC) Program

DTIC Science & Technology

2016-03-01

Secretary of Defense for Energy, Installations and Environmental, Environmental Safety and Occupational Health [OASD (EI&E/ESOH)]. The views, opinions...DEIC Program The DEIC program, which resides within the Environment, Safety , and Occupational Health (ESOH) office of the Deputy Under Secretary of...resiliency, maritime safety and security, and environmental protection in general. 7 While this

Evaluation of School Environmental Programs Regarding the Objectives for the Environmentally Literate Students, of Heraklion, Greece Prefecture

ERIC Educational Resources Information Center

Kalathak, Maria

2015-01-01

This evaluation research concerns the aims and objectives for creating the future environmentally literate citizen through the environmental programs (PEEs) of Secondary Education of Heraklion prefecture, Crete, Greece. An evaluation tool applied on the application forms and the final reports of the programs, in order to asses how sustainable they…

78 FR 5854 - Notification of the First Meetings of the U.S.-Korea FTA Environmental Affairs Council and ECA...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-28

... cooperation and will develop an environmental cooperation Work Program for the 2012-2015 period. All... the ECA, the Governments state that they plan to meet to develop and update, as appropriate, a Work Program for Environmental Cooperation. The Work Program will identify and outline environmental...

ENVIRONMENTAL TECHNOLOGY VERIFICATION AND INDOOR AIR

EPA Science Inventory

The paper discusses environmental technology verification and indoor air. RTI has responsibility for a pilot program for indoor air products as part of the U.S. EPA's Environmental Technology Verification (ETV) program. The program objective is to further the development of sel...

ENVIRONMENTAL TECHNOLOGY VERIFICATION (ETV) PROGRAM CASE STUDIES: DEMONSTRATING PROGRAM OUTCOMES, VOLUME II

EPA Science Inventory

The U.S. Environmental Protection Agency (EPA) Environmental Technology Verification (ETV) Program evaluates the performance of innovative air, water, pollution prevention and monitoring technologies that have the potential to improve human health and the environment. This bookle...

Environmental Technology Verification Program - ETV - Case Studies: Demonstrating Program Outcomes

EPA Science Inventory

The U.S. Environmental Protection Agency (EPA) Environmental Technology Verification (ETV) Program evaluates the performance of innovative air, water, pollution prevention and monitoring technologies that have the potential to improve human health and the environment. This cd con...

Environmental Science and Research Foundation annual technical report to DOE-ID, January , 1995--December 31, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-06-01

The foundation conducts an environmental monitoring and surveillance program over an area covering much of the upper Snake River Plain and provide environmental education and support services related to INEL natural resource issues. Also, the foundation, with its university affiliates, conducts ecological and radioecological research on the Idaho National Environmental Research Park. This research benefits major DOE-ID programs including waste management, environmental restoration, spent nuclear fuels, and land management issues. Major accomplishments during CY1995 can be divided into five categories: environmental surveillance program, environmental education, environmental services and support, ecological risk assessment, and research benefitting the DOE-ID mission.

Regional Environmental Monitoring and Assessment Program Data (REMAP)

EPA Pesticide Factsheets

The Regional Environmental Monitoring and Assessment Program (REMAP) was initiated to test the applicability of the Environmental Monitoring and Assessment Program (EMAP) approach to answer questions about ecological conditions at regional and local scales. Using EMAP's statistical design and indicator concepts, REMAP conducts projects at smaller geographic scales and in shorter time frames than the national EMAP program.

Sandia National Laboratories, California Environmental Management System program manual.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larsen, Barbara L.

2012-03-01

The Sandia National Laboratories, California (SNL/CA) Environmental Management System (EMS) Program Manual documents the elements of the site EMS Program. The SNL/CA EMS Program conforms to the International Standard on Environmental Management Systems, ISO 14001:2004and Department of Energy (DOE) Order 436.1. Sandia National Laboratories, California (SNL/CA) has maintained functional environmental programs to assist with regulatory compliance for more than 30 years. During 2005, these existing programs were rolled into a formal environmental management system (EMS) that expands beyond the traditional compliance focus to managing and improving environmental performance and stewardship practices for all site activities. An EMS is a setmore » of inter-related elements that represent a continuing cycle of planning, implementing, evaluating, and improving processes and actions undertaken to achieve environmental policy and goals. The SNL/CA EMS Program conforms to the International Standard for Environmental Management Systems, ISO 14001:2004 (ISO 2004). The site first received ISO 14001 certification in September 2006 and recertification in 2009. SNL/CA's EMS Program is applicable to the Sandia, Livermore site only. Although SNL/CA operates as one organizational division of the overall Sandia National Laboratories, the EMS Program is site-specific, with site-specific objectives and targets. SNL/CA (Division 8000) benefits from the organizational structure as it provides corporate level policies, procedures, and standards, and established processes that connect to and support elements of the SNL/CA EMS Program. Additionally, SNL/CA's EMS Program benefits from two corporate functional programs (Facilities Energy and Water Resource Management and Fleet Services programs) that maintain responsibility for energy management and fleet services for all Sandia locations. Each EMS element is further enhanced with site-specific processes and standards. Division 8000 has several groups operating at Sandia National Laboratories, New Mexico (SNL/NM). Although these groups, from an organizational perspective, are part of Division 8000, they are managed locally and fall under the environmental requirements specific to their New Mexico location. The New Mexico groups in Division 8000 follow the corporate EMS Program for New Mexico operations.« less

1998 Environmental Monitoring Program Report for the Idaho National Engineering and Environmental Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

L. V. Street

This report describes the calendar year 1998 compliance monitoring and environmental surveillance activities of the Lockheed Martin Idaho Technologies Company Environmental Monitoring Program performed at the Idaho National Engineering and Environmental Laboratory. This report includes results of sampling performed by the Drinking Water, Effluent, Storm Water, Groundwater Monitoring, and Environmental Surveillance Programs. This report compares the 1998 results to program-specific regulatory guidelines and past data to evaluate trends. The primary purposes of the monitoring and surveillance activities are to evaluate environmental conditions, to provide and interpret data, to verify compliance with applicable regulations or standards, and to ensure protection ofmore » public health and the environment. Surveillance of environmental media did not identify any previously unknown environmental problems or trends, which would indicate a loss of control or unplanned releases from facility operations. The INEEL complied with permits and applicable regulations, with the exception of nitrogen samples in a disposal pond effluent stream and iron and total coliform bacteria in groundwater downgradient from one disposal pond. Data collected by the Environmental Monitoring Program demonstrate that the public health and environment were protected.« less

EPA'S ENVIRONMENTAL MONITORING AND ASSESSMENT PROGRAM: AVAILABILITY OF BROAD-SCALE ENVIRONMENTAL DATA AND OPPORTUNITIES FOR USE IN ENVIRONMENTAL MODELING APPLICATIONS

EPA Science Inventory

The Environmental Monitoring and Assessment Program (EMAP) has collected a suite of environmental data over a four year period from estuarine system in the mid-Atlantic and Gulf of Mexico. ata are currently available for secondary users including environmental modelers. he data w...

24 CFR 983.58 - Environmental review.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Environmental review. 983.58... DEVELOPMENT PROJECT-BASED VOUCHER (PBV) PROGRAM Selection of PBV Owner Proposals § 983.58 Environmental review. (a) HUD environmental regulations. Activities under the PBV program are subject to HUD environmental...

24 CFR 983.58 - Environmental review.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Environmental review. 983.58... DEVELOPMENT PROJECT-BASED VOUCHER (PBV) PROGRAM Selection of PBV Owner Proposals § 983.58 Environmental review. (a) HUD environmental regulations. Activities under the PBV program are subject to HUD environmental...

78 FR 50022 - Environmental Impact Statement; Asian Longhorned Beetle Eradication Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-16

... submit comments regarding the environmental impact statement by either of the following methods: Federal..., Environmental Protection Specialist, Environmental and Risk Analysis Services, PPD, APHIS, 4700 River Road Unit...] Environmental Impact Statement; Asian Longhorned Beetle Eradication Program AGENCY: Animal and Plant Health...

Redox-controlled molecular permeability of composite-wall microcapsules

NASA Astrophysics Data System (ADS)

Ma, Yujie; Dong, Wen-Fei; Hempenius, Mark A.; Möhwald, Helmuth; Julius Vancso, G.

2006-09-01

Many smart materials in bioengineering, nanotechnology and medicine allow the storage and release of encapsulated drugs on demand at a specific location by an external stimulus. Owing to their versatility in material selection, polyelectrolyte multilayers are very promising systems in the development of microencapsulation technologies with permeation control governed by variations in the environmental conditions. Here, organometallic polyelectrolyte multilayer capsules, composed of polyanions and polycations of poly(ferrocenylsilane) (PFS), are introduced. Their preparation involved layer-by-layer self-assembly onto colloidal templates followed by core removal. PFS polyelectrolytes feature redox-active ferrocene units in the main chain. Incorporation of PFS into the capsule walls allowed us to explore the effects of a new stimulus, that is, changing the redox state, on capsule wall permeability. The permeability of these capsules could be sensitively tuned via chemical oxidation, resulting in a fast capsule expansion accompanied by a drastic permeability increase in response to a very small trigger. The substantial swelling could be suppressed by the application of an additional coating bearing common redox-inert species of poly(styrene sulfonate) (PSS-) and poly(allylamine hydrochloride) (PAH+) on the outer wall of the capsules. Hence, we obtained a unique capsule system with redox-controlled permeability and swellability with a high application potential in materials as well as in bioscience.

Programs in Environmental Studies Part Three: Special Programs.

ERIC Educational Resources Information Center

Environmental Review, 1984

1984-01-01

Presents descriptions of special programs in environmental studies. They include: historical geography (University of Illinois); internship program (Miami University); public service projects (Miami University); philosophy of ecology program (University of Montana); and a research program at the Center for Conservation Biology (Stanford…

Environmental health training: a survey of family practice residency program directors.

PubMed

Musham, C; Bellack, J P; Graber, D R; Holmes, D

1996-01-01

The Institute of Medicine and the American College of Physicians have advocated that physicians broaden their participation in the environmental aspects of medical care. Accordingly, both organizations recommend training of future primary care physicians for greater competency in and appreciation of this area of medicine. This study assessed the present emphasis on environmental health in family practice residency programs by examining the extent program directors expect graduates to have specific competencies in environmental medicine. A written survey was mailed to directors of all 393 family practice residency programs listed in the 1993 Directory of Family Practice Residency Programs. Respondents were asked to indicate the extent to which each of eight environmental health competencies was expected of their graduates. The list of environmental health competencies was based on the literature and on interviews with family practice educators. Perceptions about the "present" and "ideal" environmental health emphasis in their programs were also measured. A total of 262 completed surveys were returned for a response rate of 67%. Respondents reported that they expected their graduates to have general knowledge of and competence in environmental health areas that pertain to patient care. Competencies with social and political implications were least likely to be expected. Two thirds of respondents indicated that "minimal emphasis" is presently placed on environmental health. Seventy percent indicated that the "ideal" amount of emphasis placed on this topic is "moderate." This survey's results suggest that family practice residency program directors expect their graduates to know basic environmental health concepts and be skilled in related aspects of patient care. The development of environmental health training programs must take into account that environmental health may be viewed as a topic of secondary importance and that in most residencies, faculty expertise in this area is limited. For this reason, a self-tutoring strategy, aimed toward the educational needs of both faculty and residents, is recommended.

Formulation of advanced consumables management models: Environmental control and electrical power system performance models requirements

NASA Technical Reports Server (NTRS)

Daly, J. K.; Torian, J. G.

1979-01-01

Software design specifications for developing environmental control and life support system (ECLSS) and electrical power system (EPS) programs into interactive computer programs are presented. Specifications for the ECLSS program are at the detail design level with respect to modification of an existing batch mode program. The FORTRAN environmental analysis routines (FEAR) are the subject batch mode program. The characteristics of the FEAR program are included for use in modifying batch mode programs to form interactive programs. The EPS program specifications are at the preliminary design level. Emphasis is on top-down structuring in the development of an interactive program.

A successful programmatic structure and strategies to attract and educate students in earth and environmental sciences: an example from the University of Delaware, USA

NASA Astrophysics Data System (ADS)

Levia, Delphis

2013-04-01

The achievement of sustainable use of our natural world is one of the major issues confronting humankind today. Environmental issues are inherently complex and difficult to resolve. Successful resolution of our most pressing environmental problems, such as climate change and ocean acidification, will require well-trained earth and environmental scientists that think critically in a multi-dimensional framework at variable spatial and temporal scales. This begs the question as to how we can both attract and successfully educate students in such a way that will permit them to tackle the multitude of environmental problems currently facing society. This poster details one way to successfully attract and train students in an interdisciplinary environmental education framework by sharing: (1) some of the successful strategies and programmatic structure of the University of Delaware's undergraduate environmental programs that have grown over 60% in two years after a major programmatic revision; and (2) the current round of programmatic revisions that will complete the strategic planning process.* The interdisciplinary environmental education program at the University of Delaware has a strong programmatic core that provides students with the requisite quantitative training and field experience to solve complicated environmental issues. At the same time, the environmental program includes the social, political, and economic contexts of environmental issues. Together, these two parts of the core best equip students to mitigate environmental problems. Following a strategic planning effort, the University of Delaware is building upon past successes in training environmental scientists and managers by further reformulating its environmental programs to leverage the power of theme-based learning which complements the programmatic core in such a way to teach problem-solving skills. This poster details the multidimensional nature of the University of Delaware's environmental programs and the revised program structure that seeks to strike a balance between quantitative science, adaptive management, and solutions oriented thinking. ------------------------ *Please note that the planning process for the environmental programs was and is the collective effort of many dedicated people. Current members of the advisory Environmental Council include Drs. Delphis Levia (Program Director), Nancy Targett (Dean and Council Chair), Frank Newton, Tracy Deliberty, Tom Sims, John Madsen, Paul Imhoff, Jan Johnson, Jerry Kauffman, Murray Johnston.

ENVIRONMENTAL TECHNOLOGY VERIFICATION (ETV) PROGRAM: WET-WEATHER FLOW/SOURCE WATER PROTECTION

EPA Science Inventory

This paper presents an overview of the Environmental Protection Agency's (EPA) Environmental Technology Verification (ETV) program which was established to overcome the numerous impediments to commercialization experienced by developers of innovative environmental technologies. ...

ENVIRONMENTAL TECHNOLOGY VERIFICATION PROGRAM FOR MONITORING AND CHARACTERIZATION

EPA Science Inventory

The Environmental Technology Verification Program is a service of the Environmental Protection Agency designed to accelerate the development and commercialization of improved environmental technology through third party verification and reporting of performance. The goal of ETV i...

Proceedings of the Annual Chemical Defense Bioscience Review (5th) Held at Columbia, Maryland on 29-31 May 1985. Appendix 2

DTIC Science & Technology

1985-06-01

biocompatible enzyme-like catalyst for the rapid and specific deactivation of sys- temically sorbed nerve agents . We plan to introduce catalytic groups (thiol...mustard, seizures, respiratory failure, atropine, 2-PAM chloride, neurobehavioral effects, nerve agents , soman, cyanide, animal models, chemical casualties...Animal Model ........ .. A-541 Dr. H.L. Williams Effects of Nerve Agents on the Respiratory and e Cardiovascular Systems

Morphogenesis of the Bacillus anthracis Spore

DTIC Science & Technology

2007-02-01

product and plasmid pEO-3 (53) with BamHI and HindIII and ligated the resulting DNA fragments to build pRG23. We passaged pRG23 through E. coli GM1684...to remove debris. The removal of the exosporium was confirmed by elec- tron microscopy (data not shown). Antibody production . To produce a...O. Henriques, and S. M. Cutting (ed.), Bacterial spore formers: probiotics and emerging applications. Horizon Bioscience, Norfolk, United Kingdom

Investigating The Anti-apoptotic Effects of Shigella Flexneri Infection In Epithelial Cells

DTIC Science & Technology

2009-08-13

also been found in breast milk of convalescent mothers and most likely contribute to the reduction of disease severity in breast-fed infants (45...samples. Proteins were transferred to a nitrocellulose membrane and blocked with 5% dry milk in Tris-buffered saline (TBS). Caspases were detected by...dry milk overnight at 4°C. After washing, donkey anti- rabbit immunoglobulin G antibody conjugated to horseradish peroxidase (Amersham Biosciences

Quantitative Methods for Determining U.S. Air Force Crew Cushion Comfort

DTIC Science & Technology

2006-09-01

Directorate Biosciences and Protection Division Biomechanics Branch Wright Patterson AFB OH 45433-7947 Form Approved REPORT DOCUMENTATION PAGE OMB No...Division Biomechanics Branch Wright-Patterson AFB OH 45433-7947 9. SPONSORING I MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S...workstations were constructed utilizing ejection seat long-term flight. mockups and foot pedal assemblies modified to simulate the ACES II seat in the F-16

Experimental Analysis and Computational Modeling of Network States and Drug Responses in the PI3K/Akt/mTOR Network

DTIC Science & Technology

2010-09-01

Fixation was in 2% formaldehyde, followed by permeabilization in 100% methanol at -20 C. Blocking and incubation with primary/secondary antibodies ...was performed in Odyssey blocking buffer (LICOR). Primary antibodies were obtained from Cell Signaling, BD Biosciences, and Santa Cruz...Biotechnology, and Alexa fluor 488-, 555-, or 647-conjugated secondary antibodies were obtained from Invitrogen. Data were collected using an Applied Precision

Studying the Immunomodulatory Effects of Small Molecule Ras-Inhibitors in Animal Models of Rheumatoid Arthritis

DTIC Science & Technology

2017-10-01

found in joints, develop in the early stages of CIA creating neo-antigens that further boost the "epitope spreading" during the autoimmune response(8...ready-made ELISA kits. (eBioscience Inc.). We find that at the early stages of arthritis development FTS significantly reduces the upregulation of...reprints of manuscripts and abstracts, a curriculum vitae, patent applications, study questionnaires, and surveys , etc. “Nothing to Report

Mesothelioma: Identification of the Key Molecular Events Triggered by BAP1

DTIC Science & Technology

2015-09-01

levels as well as cytokine changes induced by BAP1. In brief, we found that BAP1 silenced HM cells (and macrophages) release more HMGB1 into the... cytokine analysis. Cells were blindly characterized with the following antibodies: CD45 (leukocytes; anti-CD45-BV711, 563709, BD Biosciences, San...following asbestos exposure. Interestingly, BAP1 has been recently shown to regulate the myeloid stem cell compartment via complex alterations of the

Breakthrough: Using Microbes to Make Advanced Biofuels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keasling, Jay

Jay Keasling, Berkeley Lab's Associate Director for Bioscience and the CEO of DOE's Joint BioEnergy Institute (JBEI), explains how special strains of microbes can convert the biomass of non-food crops and agricultural waste into fuels for cars, trucks and jet planes. Keasling's research team at JBEI has developed E.coli that can digest switchgrass and convert the plant sugars into gasoline, diesel or jet fuel, not unlike the process by which beer is brewed.

Breakthrough: Using Microbes to Make Advanced Biofuels

ScienceCinema

Keasling, Jay

2018-02-14

Jay Keasling, Berkeley Lab's Associate Director for Bioscience and the CEO of DOE's Joint BioEnergy Institute (JBEI), explains how special strains of microbes can convert the biomass of non-food crops and agricultural waste into fuels for cars, trucks and jet planes. Keasling's research team at JBEI has developed E.coli that can digest switchgrass and convert the plant sugars into gasoline, diesel or jet fuel, not unlike the process by which beer is brewed.

Approximation for limit cycles and their isochrons.

PubMed

Demongeot, Jacques; Françoise, Jean-Pierre

2006-12-01

Local analysis of trajectories of dynamical systems near an attractive periodic orbit displays the notion of asymptotic phase and isochrons. These notions are quite useful in applications to biosciences. In this note, we give an expression for the first approximation of equations of isochrons in the setting of perturbations of polynomial Hamiltonian systems. This method can be generalized to perturbations of systems that have a polynomial integral factor (like the Lotka-Volterra equation).

Retracted manuscript

PubMed Central

Klockars, Anica

2013-01-01

The following article from Small GTPases, “Scientific Yellow Journalism” by Anica Klockars and Michael J. Williams, published online on 20 September 2012  (doi: 10.4161/sgtp.22289; http://www.landesbioscience.com/journals/smallgtpases/article/22289/) by Landes Bioscience and subsequently published in print in Small GTPases 2012 3(4):201 has been retracted by agreement between the authors and the journal’s Editor in Chief, Michael J. Williams (also an author of the paper).  PMID:23485921

Molecular Engineering of Vector-Based Oncolytic and Imaging Approaches for Advanced Prostate Cancer

DTIC Science & Technology

2007-02-01

has begun to unravel, through the discovery of specific markers for lymphatic endothelial cells and their selective growth factors and receptors.13...Paraffin-embedded sections (5 lm) were stained for a vascular endothelial marker (biotinylated rat anti- mouse CD31 1:100, BD Biosciences, San Jose...CA), lymphatic endothelial markers (rabbit anti-LYVE-1 1:300, RELIATech, Braunschweig, Germany; rabbit anti-Prox1, 1:100, Novus Biologi- cals

ENVIRONMENTAL, ECONOMIC AND ENERGY IMPACTS OF MATERIAL RECOVERY FACILITIES - A MITE PROGRAM EVALUATION

EPA Science Inventory

This report documents an evaluation of the environmental, economic, and energy impacts of material recovery facilities (MRFS) conducted under the Municipal Solid Waste Innovative Technology Evaluation (MITE) Program. he MITE Program is sponsored by the U.S. Environmental Protecti...

"I Have a Hippopotamus!": Preparing Effective Early Childhood Environmental Educators

ERIC Educational Resources Information Center

Torquati, Julia; Leeper-Miller, Jennifer; Hamel, Erin; Hong, Soo-Young; Sarver, Susan; Rupiper, Michelle

2017-01-01

This article describes an early childhood teacher-preparation program that infuses environmental education and nature experiences into courses, practicum, and student-teaching experiences. Program philosophy, pedagogy, materials, and methods are described and linked to the Early Childhood Environmental Education Programs: Guidelines for…

Integrating Environmental Management of Asthma into Pediatric Health Care: What Worked and What Still Needs Improvement?

PubMed

Roberts, James R; Newman, Nicholas; McCurdy, Leyla E; Chang, Jane S; Salas, Mauro A; Eskridge, Bernard; De Ybarrondo, Lisa; Sandel, Megan; Mazur, Lynnette; Karr, Catherine J

2016-12-01

The National Environmental Education Foundation (NEEF) launched an initiative in 2005 to integrate environmental management of asthma into pediatric health care. This study, a follow-up to a 2013 study, evaluated the program's impact and assessed training results by 5 new faculty champions. We surveyed attendees at training sessions to measure knowledge and the likelihood of asking about and managing environmental triggers of asthma. To conduct the program evaluation, a workshop was held with the faculty champions and NEEF staff in which we identified major program benefits, as well as challenges and suggestions for the future. Trainee baseline knowledge of environmental triggers was low, but they reported robust improvement in environmental triggers knowledge and intention to recommend environmental management. The program has a broad, national scope, reaching more than 12 000 physicians, health care providers, and students, and some faculty champions successfully integrated materials into health record. Program barriers and future endeavors were identified.

Environmental development plan for transportation programs: FY80 update

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saricks, C.L.; Singh, M.K.; Bernard, M.J. III

1980-09-01

This is the second annual update of the environmental development plan (EDP) for transportation programs. It has been prepared as a cooperative effort of the Assistant Secretaries for Conservation and Solar Energy (ASCS) Office of Transportation Programs (CS/TP) and the Environment (ASEV) Office of Environmental Assessments. EDPs identify the ecosystem, resource, physical environment, health, safety, socioeconomic, and environmental control concerns associated with DOE programs. The programs include the research, development, demonstration, and assessment (RDD and A) of 14 transportation technologies and several strategy implementation projects. This EDP update presents a research and assessment plan for resolving any potentially adverse environmentalmore » concerns arising from these programs. The EDP process provides a framework for: incorporating environmental concerns into CS/TP planning and decision processes early to ensure they are assigned the same importance as technological, fiscal, and institutional concerns in decision making; resolving environmental concerns concurrently with energy technology and strategy development; and providing a research schedule that mitigates adverse environmental effects through sound technological design or policy analysis. This EDP also describes the status of each environmental concern and the plan for its resolution. Much of ongoing DOE reseirch and technology development is aimed at resolving concerns identified in this EDP. Each EDP is intended to be so comprehensive that no concerns escape notice. Care is taken to include any CS/TP action that may eventually require an Environmental Impact Statement. Because technology demonstration and commercialization tend to raise more environmental concerns than other portions of the transportation program, most of this EDP addresses these concerns.« less

PERFORMANCE VERIFICATION OF ANIMAL WATER TREATMENT TECHNOLOGIES THROUGH EPA'S ENVIRONMENTAL TECHNOLOGY VERIFICATION PROGRAM

EPA Science Inventory

The U.S. Environmental Protection Agency created the Environmental Technology Verification Program (ETV) to further environmental protection by accelerating the commercialization of new and innovative technology through independent performance verification and dissemination of in...

LESSONS-LEARNED AND SUCCESS STORIES FROM EPA'S REAL-TIME ENVIRONMENTAL MONITORING, DATA DELIVERY, AND PUBLIC OUTREACH PROGRAM

EPA Science Inventory

TTSD has completed a series of technology transfer and risk communication handbooks, case studies, and summary reports for community-based environmental monitoring projects under EPA's Real-Time Environmental Monitoring, Data Delivery, and Public Outreach Program. The Program tak...

Integrating hypermedia into the environmental education setting: Developing a program and evaluating its effect

NASA Astrophysics Data System (ADS)

Parker, Tehri Davenport

1997-09-01

This study designed, implemented, and evaluated an environmental education hypermedia program for use in a residential environmental education facility. The purpose of the study was to ascertain whether a hypermedia program could increase student knowledge and positive attitudes toward the environment and environmental education. A student/computer interface, based on the theory of social cognition, was developed to direct student interactions with the computer. A quasi-experimental research design was used. Students were randomly assigned to either the experimental or control group. The experimental group used the hypermedia program to learn about the topic of energy. The control group received the same conceptual information from a teacher/naturalist. An Environmental Awareness Quiz was administered to measure differences in the students' cognitive understanding of energy issues. Students participated in one on one interviews to discuss their attitudes toward the lesson and the overall environmental education experience. Additionally, members of the experimental group were tape recorded while they used the hypermedia program. These tapes were analyzed to identify aspects of the hypermedia program that promoted student learning. The findings of this study suggest that computers, and hypermedia programs, can be integrated into residential environmental education facilities, and can assist environmental educators in meeting their goals for students. The study found that the hypermedia program was as effective as the teacher/naturalist for teaching about environmental education material. Students who used the computer reported more positive attitudes toward the lesson on energy, and thought that they had learned more than the control group. Students in the control group stated that they did not learn as much as the computer group. The majority of students had positive attitudes toward the inclusion of computers in the camp setting, and stated that they were a good way to learn about environmental education material. This study also identified lack of social skills as a barrier to social cognition among mixed gender groups using the computer program.

Dehydration pathways of 1-propanol on HZSM-5 in the presence and absence of water

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhi, Yuchun; Shi, Hui; Mu, Linyu

The Brønsted acid-catalyzed gas-phase dehydration of 1-propanol (0.075-4 kPa) was studied on zeolite H-MFI (Si/Al = 26, containing minimal amounts of extraframework Al moieties) in the absence and presence of co-fed water (0-2.5 kPa) at 413-443 K. It is shown that propene can be formed from monomeric and dimeric adsorbed 1-propanol. The stronger adsorption of 1-propanol relative to water indicates that the reduced dehydration rates in the presence of water are not a consequence of the competitive adsorption between 1-propanol and water. Instead, the deleterious effect is related to the different extents of stabilization of adsorbed intermediates and the relevantmore » elimination/substitution transition states by water. Water stabilizes the adsorbed 1-propanol monomer significantly more than the elimination transition state, leading to a higher activation barrier and a greater entropy gain for the rate-limiting step, which eventually leads to propene. In a similar manner, an excess of 1-propanol stabilizes the adsorbed state of 1-propanol more than the elimination transition state. In comparison with the monomer-mediated pathway, adsorbed dimer and the relevant transition states for propene and ether formation are similarly, while less effectively, stabilized by intrazeolite water molecules. This work was supported by the US Department of Energy, Office of Science, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences, and Biosciences, and was performed in part using the Molecular Sciences Computing Facility (MSCF) in the William R. Wiley Environmental Molecular Sciences Laboratory, a DOE national scientific user facility sponsored by the DOE’s Office of Biological and Environmental Research and located and the Pacific Northwest National Laboratory (PNNL). PNNL is operated by Battelle for DOE.« less

Heterolysis of H2 Across a Classical Lewis Pair, 2,6-Lutidine-BCl3: Synthesis, Characterization, and Mechanism

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ginovska-Pangovska, Bojana; Autrey, Thomas; Parab, Kshitij K.

We report on a combined computational and experimental study of the activation of hydrogen using for 2,6-lutidine (Lut)/BCl3 Lewis pairs. Herein we describe the synthetic approach used to obtain a new FLP, Lut-BCl3 that activates molecular H2 at ~10 bar, 100 °C in toluene or lutidine as the solvent. The resulting compound is an unexpected neutral hydride, LutBHCl2, rather than the ion pair, which we attribute to ligand redistribution. The mechanism for activation was modeled with density functional theory and accurate G3(MP2)B3 theory. The dative bond in Lut-BCl3 is calculated to have a bond enthalpy of 15 kcal/mol. The separatedmore » pair is calculated to react with H2 and form the [LutH+][HBCl3–] ion pair with a barrier of 13 kcal/mol. Metathesis with LutBCl3 produces LutBHCl2 and [LutH][BCl4]. The overall reaction is exothermic by 8.5 kcal/mol. An alternative pathway was explored involving lutidine–borenium cation pair activating H2. This work was supported by the U.S. Department of Energy's (DOE) Office of Basic Energy Sciences, Division of Chemical Sciences, Biosciences, and Geosciences, and was performed in part using the Molecular Science Computing Facility (MSCF) in the William R. Wiley Environmental Molecular Sciences Laboratory, a DOE national scientific user facility sponsored by the Department of Energy's Office of Biological and Environmental Research and located at the Pacific Northwest National Laboratory (PNNL). PNNL is operated by Battelle for DOE.« less

Characterization of oxygen and titanium diffusion at the anatase TiO2(001) surface

DOE Office of Scientific and Technical Information (OSTI.GOV)

Herman, Gregory S.; Zehr, Robert T.; Henderson, Michael A.

2013-06-01

The diffusion of intrinsic defects in a single crystal anatase TiO2(001) film was explored by isotopic labeling and static secondary ion mass spectrometry. Using both 46Ti and 18O as isotopic labels, we show that the anatase surface responds to redox imbalances by diffusion of both Ti and O into the bulk under vacuum reduction and (at least) Ti from the bulk to the surface during oxidation. The diffusion of Ti between the bulk and surface in anatase TiO2(001) closely resembles what was observed in the literature for the rutile TiO2(110) surface, however the latter is not known to have oxygenmore » diffusion between the bulk and surface under typical ultrahigh vacuum conditions. We speculate that the open lattice of the anatase bulk structure may facilitate independent diffusion of both point defects (Ti interstitials and O vacancies) or concerted diffusion of "TiO" subunits. The authors gratefully acknowledge S.A. Chambers of Pacific Northwest National Laboratory (PNNL) for providing the anatase samples. This research was supported by the U.S. Department of Energy (DOE) Office of Basic Energy Sciences, Chemical Sciences, Geosciences, and Biosciences Division, the Office of Naval Research Contract Number 200CAR262, and the Oregon Nanoscience and Microtechnologies Institute. PNNL is operated for the U.S. DOE by Battelle under Contract Number DE05-AC76RL0 1830. The research was performed in the William R. Wiley Environmental Molecular Sciences Laboratory, a national scientific user facility funded by the U.S. DOE Office of Biological and Environmental Research.« less

About the Clusters Program

EPA Pesticide Factsheets

The Environmental Technology Innovation Clusters Program advises cluster organizations, encourages collaboration between clusters, tracks U.S. environmental technology clusters, and connects EPA programs to cluster needs.

Improving Voluntary Environmental Management Programs: Facilitating Learning and Adaptation

NASA Astrophysics Data System (ADS)

Genskow, Kenneth D.; Wood, Danielle M.

2011-05-01

Environmental planners and managers face unique challenges understanding and documenting the effectiveness of programs that rely on voluntary actions by private landowners. Programs, such as those aimed at reducing nonpoint source pollution or improving habitat, intend to reach those goals by persuading landowners to adopt behaviors and management practices consistent with environmental restoration and protection. Our purpose with this paper is to identify barriers for improving voluntary environmental management programs and ways to overcome them. We first draw upon insights regarding data, learning, and adaptation from the adaptive management and performance management literatures, describing three key issues: overcoming information constraints, structural limitations, and organizational culture. Although these lessons are applicable to a variety of voluntary environmental management programs, we then present the issues in the context of on-going research for nonpoint source water quality pollution. We end the discussion by highlighting important elements for advancing voluntary program efforts.

Oil shale development and its environmental considerations

USGS Publications Warehouse

Stone, R.T.; Johnson, H.; Decora, A.

1974-01-01

The petroleum shortage recently experienced by many nations throughout the world has created an intense interest in obtaining new and supplemental energy sources. In the United States, this interest has been centered on oil shale. Any major action by the federal government having significant environmental effects requires compliance with the National Environmental Policy Act of 1969 (NEPA). Since most oil shale is found on federal lands, and since its development involves significant environmental impacts, leasing oil shale lands to private interests must be in compliance with NEPA. For oil shale, program planning began at approximately the same time that NEPA was signed into law. By structuring the program to permit a resource and technological inventory by industry and the federal agencies, the Department of the Interior was able simultaneously to conduct the environmental assessments required by the act. This required: 1. Clearly defined program objections; 2. An organization which could integrate public policy with diverse scientific disciplines and environmental concerns; and 3. Flexible decisionmaking to adjust to policy changes as well as to evolving interpretations on EPA as clarified by court decisions. This paper outlines the program, the organization structure that was created for this specific task, and the environmental concerns which were investigated. The success of the program has been demonstrated by meeting the requirements of NEPA, without court challenge, and by industry's acceptance of a leasing program that included the most stringent environmental protection provisions ever required. The need for energy development has spurred the acceptance of the program. However, by its awareness and willingness to meet the environmental challenges of the future, industry has shown a reasonable understanding of its commitments. The pros and cons of development were publicly considered in hearings and analyzed in the final environmental statement. This action aided greatly in preventing legal challenges. The prototype oil shale program is now under way and this new energy source, developed with strict environmental safeguards, may soon be available to our nation.

40 CFR 52.1690 - Small business technical and environmental compliance assistance program.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) New York § 52.1690 Small business technical and environmental compliance assistance program. On January 11, 1993, the New York State Department of Environmental Conservation submitted a plan for the... Assistance Program for incorporation in the New York state implementation plan. This plan meets the...

40 CFR 52.2732 - Small business technical and environmental compliance assistance program.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) Puerto Rico § 52.2732 Small business technical and environmental compliance assistance program. On November 16, 1992, the Puerto Rico Environmental Quality Board submitted a plan for the... Assistance Program for incorporation in the Puerto Rico state implementation plan. This plan meets the...

40 CFR 52.2732 - Small business technical and environmental compliance assistance program.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) Puerto Rico § 52.2732 Small business technical and environmental compliance assistance program. On November 16, 1992, the Puerto Rico Environmental Quality Board submitted a plan for the... Assistance Program for incorporation in the Puerto Rico state implementation plan. This plan meets the...

40 CFR 52.2732 - Small business technical and environmental compliance assistance program.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) Puerto Rico § 52.2732 Small business technical and environmental compliance assistance program. On November 16, 1992, the Puerto Rico Environmental Quality Board submitted a plan for the... Assistance Program for incorporation in the Puerto Rico state implementation plan. This plan meets the...