Sample records for environmentally triggered setting

  1. Potential Environmental Triggers of Myositis

    DTIC Science & Technology

    2012-10-01

    Myositis PRINCIPAL INVESTIGATOR: Robert Goldberg CONTRACTING ORGANIZATION: The...TYPE Annual Report 3. DATES COVERED 12September2011-11September2012 4. TITLE AND SUBTITLE Potential Environmental Triggers of Myositis 5a...10 INTRODUCTION: The Potential Environmental Triggers of Myositis

  2. Reducing Environmental Allergic Triggers: Policy Issues.

    PubMed

    Abramson, Stuart L

    The implementation of policies to reduce environmental allergic triggers can be an important adjunct to optimal patient care for allergic rhinitis and allergic asthma. Policies at the local level in schools and other public as well as private buildings can make an impact on disease morbidity. Occupational exposures for allergens have not yet been met with the same rigorous policy standards applied for exposures to toxicants by Occupational Safety and Health Administration. Further benefit may be obtained through policies by local, county, state, and national governments, and possibly through international cooperative agreements. The reduction of allergenic exposures can and should be affected by policies with strong scientific, evidence-based derivation. However, a judicious application of the precautionary principle may be needed in circumstances where the health effect of inaction could lead to more serious threats to vulnerable populations with allergic disease. This commentary covers the scientific basis, current implementation, knowledge gaps, and pro/con views on policy issues in reducing environmental allergic triggers. Copyright © 2017 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  3. Environmental insults: critical triggers for amyotrophic lateral sclerosis.

    PubMed

    Yu, Bing; Pamphlett, Roger

    2017-01-01

    Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterised by a rapid loss of lower and upper motor neurons. As a complex disease, the ageing process and complicated gene-environment interactions are involved in the majority of cases. Significant advances have been made in unravelling the genetic susceptibility to ALS with massively parallel sequencing technologies, while environmental insults remain a suspected but largely unexplored source of risk. Several studies applying the strategy of Mendelian randomisation have strengthened the link between environmental insults and ALS, but none so far has proved conclusive. We propose a new ALS model which links the current knowledge of genetic factors, ageing and environmental insults. This model provides a mechanism as to how ALS is initiated, with environmental insults playing a critical role. The available evidence has suggested that inherited defect(s) could cause mitochondrial dysfunction, which would establish the primary susceptibility to ALS. Further study of the underlying mechanism may shed light on ALS pathogenesis. Environmental insults are a critical trigger for ALS, particularly in the aged individuals with other toxicant susceptible genes. The identification of ALS triggers could lead to preventive strategies for those individuals at risk.

  4. Influence of central set on anticipatory and triggered grip-force adjustments

    NASA Technical Reports Server (NTRS)

    Winstein, C. J.; Horak, F. B.; Fisher, B. E.; Peterson, B. W. (Principal Investigator)

    2000-01-01

    The effects of predictability of load magnitude on anticipatory and triggered grip-force adjustments were studied as nine normal subjects used a precision grip to lift, hold, and replace an instrumented test object. Experience with a predictable stimulus has been shown to enhance magnitude scaling of triggered postural responses to different amplitudes of perturbations. However, this phenomenon, known as a central-set effect, has not been tested systematically for grip-force responses in the hand. In our study, predictability was manipulated by applying load perturbations of different magnitudes to the test object under conditions in which the upcoming load magnitude was presented repeatedly or under conditions in which the load magnitudes were presented randomly, each with two different pre-load grip conditions (unconstrained and constrained). In constrained conditions, initial grip forces were maintained near the minimum level necessary to prevent pre-loaded object slippage, while in unconstrained conditions, no initial grip force restrictions were imposed. The effect of predictable (blocked) and unpredictable (random) load presentations on scaling of anticipatory and triggered grip responses was tested by comparing the slopes of linear regressions between the imposed load and grip response magnitude. Anticipatory and triggered grip force responses were scaled to load magnitude in all conditions. However, regardless of pre-load grip force constraint, the gains (slopes) of grip responses relative to load magnitudes were greater when the magnitude of the upcoming load was predictable than when the load increase was unpredictable. In addition, a central-set effect was evidenced by the fewer number of drop trials in the predictable relative to unpredictable load conditions. Pre-load grip forces showed the greatest set effects. However, grip responses showed larger set effects, based on prediction, when pre-load grip force was constrained to lower levels. These

  5. Autoantigen cross-reactive environmental antigen can trigger multiple sclerosis-like disease.

    PubMed

    Reynolds, Catherine J; Sim, Malcolm J W; Quigley, Kathryn J; Altmann, Daniel M; Boyton, Rosemary J

    2015-05-13

    Multiple sclerosis is generally considered an autoimmune disease resulting from interaction between predisposing genes and environmental factors, together allowing immunological self-tolerance to be compromised. The precise nature of the environmental inputs has been elusive, infectious agents having received considerable attention. A recent study generated an algorithm predicting naturally occurring T cell receptor (TCR) ligands from the proteome database. Taking the example of a multiple sclerosis patient-derived anti-myelin TCR, the study identified a number of stimulatory, cross-reactive peptide sequences from environmental and human antigens. Having previously generated a spontaneous multiple sclerosis (MS) model through expression of this TCR, we asked whether any of these could indeed function in vivo to trigger CNS disease by cross-reactive activation. A number of myelin epitope cross-reactive epitopes could stimulate T cell immunity in this MS anti-myelin TCR transgenic model. Two of the most stimulatory of these 'environmental' epitopes, from Dictyostyelium slime mold and from Emiliania huxleyi, were tested for the ability to induce MS-like disease in the transgenics. We found that immunization with cross-reactive peptide from Dictyostyelium slime mold (but not from E. huxleyi) induces severe disease. These specific environmental epitopes are unlikely to be common triggers of MS, but this study suggests that our search for the cross-reactivity triggers of autoimmune activation leading to MS should encompass epitopes not just from the 'infectome' but also from the full environmental 'exposome.'

  6. Sensitizing events as trigger for discursive renewal and institutional change in Flanders’ environmental health approach, 1970s-1990s

    PubMed Central

    2013-01-01

    Background Sensitizing events may trigger and stimulate discursive renewal. From a discursive institutional perspective, changing discourses are the driving force behind the institutional dynamics of policy domains. Theoretically informed by discursive institutionalism, this article assesses the impact of a series of four sensitizing events that triggered serious environmental health concerns in Flanders between the 1970s till the 1990s, and led onto the gradual institutionalization of a Flemish environmental health arrangement. Methods The Policy Arrangement Approach is used as the analytical framework to structure the empirical results of the historical analysis based on document analysis and in-depth interviews. Results Until the 1990s, environmental health was characterized as an ad hoc policy field in Flanders, where agenda setting was based on sensitizing events – also referred to as incident-driven. Each of these events contributed to a gradual rethinking of the epistemological discourses about environmental health risks and uncertainties. These new discourses were the driving forces behind institutional dynamics as they gradually resulted in an increased need for: 1) long-term, policy-oriented, interdisciplinary environmental health research; 2) policy coordination and integration between the environmental and public health policy fields; and 3) new forms of science-policy interactions based on mutual learning. These changes are desirable in order to detect environmental health problems as fast as possible, to react immediately and communicate appropriately. Conclusions The series of four events that triggered serious environmental health concerns in Flanders provided the opportunity to rethink and re-organize the current affairs concerning environmental health and gradually resulted into the institutionalization of a Flemish environmental health arrangement. PMID:23758822

  7. Type 1 diabetes: prospective cohort studies for identification of the environmental trigger.

    PubMed

    Rønningen, Kjersti S

    2013-12-01

    Type 1 diabetes (T1D) is one of the most common chronic diseases with childhood onset, and the disease incidence has increased two to fivefold over the past half century by as yet unknown means. T1D occurs when the body's immune system turns against itself, destroying in a very specific and targeted way-the pancreatic β-cells. T1D results from poorly defined interactions between susceptibility genes and environmental determinants. In contrast to the rapid progress in finding T1D genes, identification and confirmation of environmental determinants remain a formidable challenge. This review article will give an overview of ongoing prospective cohort studies aiming to identify the environmental trigger(s) causing T1D.

  8. Mercury enrichment indicates volcanic triggering of Valanginian environmental change

    PubMed Central

    Charbonnier, Guillaume; Morales, Chloé; Duchamp-Alphonse, Stéphanie; Westermann, Stéphane; Adatte, Thierry; Föllmi, Karl B.

    2017-01-01

    The Valanginian stage (Early Cretaceous) includes an episode of significant environmental changes, which are well defined by a positive δ13C excursion. This globally recorded excursion indicates important perturbations in the carbon cycle, which has tentatively been associated with a pulse in volcanic activity and the formation of the Paraná-Etendeka large igneous province (LIP). Uncertainties in existing age models preclude, however, its positive identification as a trigger of Valanginian environmental changes. Here we report that in Valanginian sediments recovered from a drill core in Wąwał (Polish Basin, Poland), and from outcrops in the Breggia Gorge (Lombardian Basin, southern Switzerland), and Orpierre and Angles (Vocontian Basin, SE France), intervals at or near the onset of the positive δ13C excursion are significantly enriched in mercury (Hg). The persistence of the Hg anomaly in Hg/TOC, Hg/phyllosilicate, and Hg/Fe ratios shows that organic-matter scavenging and/or adsorbtion onto clay minerals or hydrous iron oxides only played a limited role. Volcanic outgassing was most probably the primary source of the Hg enrichments, which demonstrate that an important magmatic pulse triggered the Valanginian environmental perturbations. PMID:28106091

  9. Mercury enrichment indicates volcanic triggering of Valanginian environmental change

    NASA Astrophysics Data System (ADS)

    Charbonnier, Guillaume; Morales, Chloé; Duchamp-Alphonse, Stéphanie; Westermann, Stéphane; Adatte, Thierry; Föllmi, Karl B.

    2017-01-01

    The Valanginian stage (Early Cretaceous) includes an episode of significant environmental changes, which are well defined by a positive δ13C excursion. This globally recorded excursion indicates important perturbations in the carbon cycle, which has tentatively been associated with a pulse in volcanic activity and the formation of the Paraná-Etendeka large igneous province (LIP). Uncertainties in existing age models preclude, however, its positive identification as a trigger of Valanginian environmental changes. Here we report that in Valanginian sediments recovered from a drill core in Wąwał (Polish Basin, Poland), and from outcrops in the Breggia Gorge (Lombardian Basin, southern Switzerland), and Orpierre and Angles (Vocontian Basin, SE France), intervals at or near the onset of the positive δ13C excursion are significantly enriched in mercury (Hg). The persistence of the Hg anomaly in Hg/TOC, Hg/phyllosilicate, and Hg/Fe ratios shows that organic-matter scavenging and/or adsorbtion onto clay minerals or hydrous iron oxides only played a limited role. Volcanic outgassing was most probably the primary source of the Hg enrichments, which demonstrate that an important magmatic pulse triggered the Valanginian environmental perturbations.

  10. Environmental triggers and avoidance in the management of asthma

    PubMed Central

    Gautier, Clarisse; Charpin, Denis

    2017-01-01

    Identifying asthma triggers forms the basis of environmental secondary prevention. These triggers may be allergenic or nonallergenic. Allergenic triggers include indoor allergens, such as house dust mites (HDMs), molds, pets, cockroaches, and rodents, and outdoor allergens, such as pollens and molds. Clinical observations provide support for the role of HDM exposure as a trigger, although avoidance studies provide conflicting results. Molds and their metabolic products are now considered to be triggers of asthma attacks. Pets, dogs, and especially cats can undoubtedly trigger asthmatic symptoms in sensitized subjects. Avoidance is difficult and rarely adhered to by families. Cockroach allergens contribute to asthma morbidity, and avoidance strategies can lead to clinical benefit. Mouse allergens are mostly found in inner-city dwellings, but their implication in asthma morbidity is debated. In the outdoors, pollens can induce seasonal asthma in sensitized individuals. Avoidance relies on preventing pollens from getting into the house and on minimizing seasonal outdoor exposure. Outdoor molds may lead to severe asthma exacerbations. Nonallergenic triggers include viral infections, active and passive smoking, meteorological changes, occupational exposures, and other triggers that are less commonly involved. Viral infection is the main asthma trigger in children. Active smoking is associated with higher asthma morbidity, and smoking cessation interventions should be personalized. Passive smoking is also a risk factor for asthma exacerbation. The implementation of public smoking bans has led to a reduction in the hospitalization of asthmatic children. Air pollution levels have been linked with asthmatic symptoms, a decrease in lung function, and increased emergency room visits and hospitalizations. Since avoidance is not easy to achieve, clean air policies remain the most effective strategy. Indoor air is also affected by air pollutants, such as cigarette smoke and

  11. Setting Environmental Standards

    ERIC Educational Resources Information Center

    Fishbein, Gershon

    1975-01-01

    Recent court decisions have pointed out the complexities involved in setting environmental standards. Environmental health is composed of multiple causative agents, most of which work over long periods of time. This makes the cause-and-effect relationship between health statistics and environmental contaminant exposures difficult to prove in…

  12. Environmental triggers of thyroiditis: hepatitis C and interferon-α.

    PubMed

    Menconi, F; Hasham, A; Tomer, Y

    2011-01-01

    Autoimmune thyroid diseases (AITD) are postulated to develop as a result of a complex interplay between several genetic and environmental influences. The pathogenesis of AITD is still not clearly defined. However, among the implicated triggers (e.g. iodine, infections, medications), more recent data confirmed strong associations of AITD with the hepatitis C virus (HCV) infection and interferon-α (IFNα) therapy. Moreover, it is likely that HCV and IFN act in synergism to trigger AITD in patients. Indeed, approximately 40% of HCV patients develop either clinical or subclinical disease while receiving IFNα. Interferon induced thyroiditis (IIT) can manifest as non-autoimmune thyroiditis (presenting as destructive thyroiditis, or non-autoimmune hypothyroidism), or autoimmune thyroiditis [presenting with clinical features of Graves' disease (GD) or Hashimoto's thyroiditis (HT)]. Although not yet clearly understood, it is thought that IFNα can induce thyroiditis via both immune stimulatory and direct toxic effects on the thyroid. In view of the high frequency of IIT, routine screening and surveillance of HCV patients receiving IFNα is recommended to avoid the complications, such as cardiac arrhythmias, associated with thyrotoxicosis. In summary, IIT is a common clinical problem that can be readily diagnosed with routine thyroid function screening of HCV patients receiving IFN. The treatment of IIT consists of the standard therapy for differing clinical manifestations of IIT such as GD, HT, or destructive thyroiditis. However, anti-thyroid medications are not recommended in this setting since they can potentially be hepatotoxic.

  13. Environmental triggers in IBD: a review of progress and evidence.

    PubMed

    Ananthakrishnan, Ashwin N; Bernstein, Charles N; Iliopoulos, Dimitrios; Macpherson, Andrew; Neurath, Markus F; Ali, Raja A Raja; Vavricka, Stephan R; Fiocchi, Claudio

    2018-01-01

    A number of environmental factors have been associated with the development of IBD. Alteration of the gut microbiota, or dysbiosis, is closely linked to initiation or progression of IBD, but whether dysbiosis is a primary or secondary event is unclear. Nevertheless, early-life events such as birth, breastfeeding and exposure to antibiotics, as well as later childhood events, are considered potential risk factors for IBD. Air pollution, a consequence of the progressive contamination of the environment by countless compounds, is another factor associated with IBD, as particulate matter or other components can alter the host's mucosal defences and trigger immune responses. Hypoxia associated with high altitude is also a factor under investigation as a potential new trigger of IBD flares. A key issue is how to translate environmental factors into mechanisms of IBD, and systems biology is increasingly recognized as a strategic tool to unravel the molecular alterations leading to IBD. Environmental factors add a substantial level of complexity to the understanding of IBD pathogenesis but also promote the fundamental notion that complex diseases such as IBD require complex therapies that go well beyond the current single-agent treatment approach. This Review describes the current conceptualization, evidence, progress and direction surrounding the association of environmental factors with IBD.

  14. Local nutrient regimes determine site-specific environmental triggers of cyanobacterial and microcystin variability in urban lakes

    NASA Astrophysics Data System (ADS)

    Sinang, S. C.; Reichwaldt, E. S.; Ghadouani, A.

    2014-10-01

    Toxic cyanobacterial blooms in urban lakes present serious health hazards to humans and animals and require effective management strategies. In the management of toxic cyanobacteria blooms, understanding the roles of environmental factors is crucial. To date, a range of environmental factors have been proposed as potential triggers for the spatiotemporal variability of cyanobacterial biomass and microcystins in freshwater systems. However, the environmental triggers of cyanobacteria and microcystin variability remain a subject of debate due to contrasting findings. This issue has raised the question if the environmental triggers are site-specific and unique between water bodies. In this study, we investigated the site-specificity of environmental triggers for cyanobacterial bloom and cyanotoxins dynamics. Our study suggests that cyanobacterial dominance and cyanobacterial microcystin content variability were significantly correlated to phosphorus and iron concentrations. However, the correlations between phosphorus and iron with cyanobacterial biomass and microcystin variability were not consistent between lakes, thus suggesting a site specificity of these environmental factors. The discrepancies in the correlations could be explained by differences in local nutrient concentration and the cyanobacterial community in the systems. The findings of this study suggest that identification of site-specific environmental factors under unique local conditions is an important strategy to enhance positive outcomes in cyanobacterial bloom control measures.

  15. Warning Triggers in Environmental Hazards: Who Should Be Warned to Do What and When?

    PubMed

    Cova, Thomas J; Dennison, Philip E; Li, Dapeng; Drews, Frank A; Siebeneck, Laura K; Lindell, Michael K

    2017-04-01

    Determining the most effective public warnings to issue during a hazardous environmental event is a complex problem. Three primary questions need to be answered: Who should take protective action? What is the best action? and When should this action be initiated? Warning triggers provide a proactive means for emergency managers to simultaneously answer these questions by recommending that a target group take a specified protective action if a preset environmental trigger condition occurs (e.g., warn a community to evacuate if a wildfire crosses a proximal ridgeline). Triggers are used to warn the public across a wide variety of environmental hazards, and an improved understanding of their nature and role promises to: (1) advance protective action theory by unifying the natural, built, and social themes in hazards research into one framework, (2) reveal important information about emergency managers' risk perception, situational awareness, and threat assessment regarding threat behavior and public response, and (3) advance spatiotemporal models for representing the geography and timing of disaster warning and response (i.e., a coupled natural-built-social system). We provide an overview and research agenda designed to advance our understanding and modeling of warning triggers. © 2016 Society for Risk Analysis.

  16. Engineered modular biomaterial logic gates for environmentally triggered therapeutic delivery

    NASA Astrophysics Data System (ADS)

    Badeau, Barry A.; Comerford, Michael P.; Arakawa, Christopher K.; Shadish, Jared A.; Deforest, Cole A.

    2018-03-01

    The successful transport of drug- and cell-based therapeutics to diseased sites represents a major barrier in the development of clinical therapies. Targeted delivery can be mediated through degradable biomaterial vehicles that utilize disease biomarkers to trigger payload release. Here, we report a modular chemical framework for imparting hydrogels with precise degradative responsiveness by using multiple environmental cues to trigger reactions that operate user-programmable Boolean logic. By specifying the molecular architecture and connectivity of orthogonal stimuli-labile moieties within material cross-linkers, we show selective control over gel dissolution and therapeutic delivery. To illustrate the versatility of this methodology, we synthesized 17 distinct stimuli-responsive materials that collectively yielded all possible YES/OR/AND logic outputs from input combinations involving enzyme, reductant and light. Using these hydrogels we demonstrate the first sequential and environmentally stimulated release of multiple cell lines in well-defined combinations from a material. We expect these platforms will find utility in several diverse fields including drug delivery, diagnostics and regenerative medicine.

  17. Engineered modular biomaterial logic gates for environmentally triggered therapeutic delivery.

    PubMed

    Badeau, Barry A; Comerford, Michael P; Arakawa, Christopher K; Shadish, Jared A; DeForest, Cole A

    2018-03-01

    The successful transport of drug- and cell-based therapeutics to diseased sites represents a major barrier in the development of clinical therapies. Targeted delivery can be mediated through degradable biomaterial vehicles that utilize disease biomarkers to trigger payload release. Here, we report a modular chemical framework for imparting hydrogels with precise degradative responsiveness by using multiple environmental cues to trigger reactions that operate user-programmable Boolean logic. By specifying the molecular architecture and connectivity of orthogonal stimuli-labile moieties within material cross-linkers, we show selective control over gel dissolution and therapeutic delivery. To illustrate the versatility of this methodology, we synthesized 17 distinct stimuli-responsive materials that collectively yielded all possible YES/OR/AND logic outputs from input combinations involving enzyme, reductant and light. Using these hydrogels we demonstrate the first sequential and environmentally stimulated release of multiple cell lines in well-defined combinations from a material. We expect these platforms will find utility in several diverse fields including drug delivery, diagnostics and regenerative medicine.

  18. Luminex and other multiplex high throughput technologies for the identification of, and host response to, environmental triggers of type 1 diabetes.

    PubMed

    Purohit, Sharad; Sharma, Ashok; She, Jin-Xiong

    2015-01-01

    Complex interactions between a series of environmental factors and genes result in progression to clinical type 1 diabetes in genetically susceptible individuals. Despite several decades of research in the area, these interactions remain poorly understood. Several studies have yielded associations of certain foods, infections, and immunizations with the onset and progression of diabetes autoimmunity, but most findings are still inconclusive. Environmental triggers are difficult to identify mainly due to (i) large number and complex nature of environmental exposures, including bacteria, viruses, dietary factors, and environmental pollutants, (ii) reliance on low throughput technology, (iii) less efforts in quantifying host response, (iv) long silent period between the exposure and clinical onset of T1D which may lead to loss of the exposure fingerprints, and (v) limited sample sets. Recent development in multiplex technologies has enabled systematic evaluation of different classes of molecules or macroparticles in a high throughput manner. However, the use of multiplex assays in type 1 diabetes research is limited to cytokine assays. In this review, we will discuss the potential use of multiplex high throughput technologies in identification of environmental triggers and host response in type 1 diabetes.

  19. Generator Set Environmental and Stability Testing

    DTIC Science & Technology

    2015-03-01

    UNCLASSIFIED GENERATOR SET ENVIRONMENTAL AND STABILITY TESTING INTERIM REPORT TFLRF No. 460 by Gregory A. Hansen Edwin A...it to the originator. UNCLASSIFIED GENERATOR SET ENVIRONMENTAL AND STABILITY TESTING INTERIM REPORT TFLRF No. 460 by...TITLE AND SUBTITLE Generator Set Environmental and Stability Testing 5a. CONTRACT NUMBER W56HZV-09-C-0100 5b. GRANT NUMBER 5c. PROGRAM

  20. Quivering on the brink: Common observations of turbidity current frequency and triggering in disparate settings

    NASA Astrophysics Data System (ADS)

    Clare, M. A.; Rosenberger, K. J.; Parsons, D. R.; Gales, J. A.; Gwiazda, R.; Paull, C. K.; Talling, P.; Cartigny, M.; Azpiroz, M.; Pope, E.; Hizzett, J. L.; Hughes Clarke, J. E.

    2017-12-01

    Turbidity currents pose a hazard to seafloor infrastructure, convey sediment to the deep sea, and provide nutrients to benthic communities. Despite their importance, we still know little about specifically how and when such powerful long run-out flows are triggered, and how strongly different trigger mechanisms control flow behaviour. New advances in direct monitoring now allow us to precisely constrain turbidity current frequency and test the efficiency of previously hypothesised triggering mechanisms. Here, we document the timing of sub-annual turbidity currents based on direct measurements using Acoustic Doppler Current Profilers at four different sites. Two sites are located at offshore fjord-head deltas in British Columbia (Squamish delta & Bute Inlet), which are fed by meltwater in spring and summer. The third is the deep-water Congo Canyon, which is located offshore Angola, and is fed by the second largest river in the world. Fourth is the Monterey Canyon, offshore California, which does not have a direct link to a river and is instead fed by littoral drift. Despite the differences in scale and setting, all of the sites show similar trends in turbidity current frequency. The first commonality is that flow timing is typically delayed (hours to weeks) following periods of rapid sediment discharge, rather than immediately coincident with them. The second commonality is that flows are rare (typically they do not occur at all) for at least half of the year in each of the sites. Instead, flows are clustered within a specific time window. We underline the importance of preconditioning prior to, and during that time window and propose that an environmental threshold must be exceeded in order to "switch on" these systems. This threshold primarily relates to magnitude of sediment delivery at the head of the channel or canyon. Once that threshold is surpassed, then systems are primed for action, quivering on the brink, allowing even small external perturbations to

  1. A Cook, A Cardinal, His Priests, and the Press: Deviance as a Trigger for Intermedia Agenda Setting.

    ERIC Educational Resources Information Center

    Breen, Michael J.

    1997-01-01

    Uses content analysis to examine the changes in trends in the aftermath of deviant acts by individual members of the clergy, given that such acts are "triggering events" for further negative stories. Finds strong media agenda-setting effects of the negative triggering events on subsequent coverage of the clergy in general. (SR)

  2. Community organizing network for environmental health: using a community health development approach to increase community capacity around reduction of environmental triggers.

    PubMed

    Parker, Edith A; Chung, Lynna K; Israel, Barbara A; Reyes, Angela; Wilkins, Donele

    2010-04-01

    The Community Organizing Network for Environmental Health (CONEH), a project of Community Action Against Asthma, used a community health development approach to improve children's asthma-related health through increasing the community's capacity to reduce physical and social environmental triggers for asthma. Three community organizers were hired to work with community groups and residents in neighborhoods in Detroit on the priority areas of air quality, housing, and citizen involvement in the environmental project and policy decision-making. As part of the evaluation of the CONEH project, 20 one-on-one semi-structured, in-depth interviews were conducted between August and November 2005 involving steering committee members, staff members, and key community organization staff and/or community members. Using data from the evaluation of the CONEH project, this article identifies the dimensions of community capacity that were enhanced as part of a CBPR community health development approach to reducing physical and social environmental triggers associated with childhood asthma and the factors that facilitated or inhibited the enhancement of community capacity.

  3. Community Organizing Network for Environmental Health: Using a Community Health Development Approach to Increase Community Capacity around Reduction of Environmental Triggers

    PubMed Central

    Chung, Lynna K.; Israel, Barbara A.; Reyes, Angela; Wilkins, Donele

    2010-01-01

    The Community Organizing Network for Environmental Health (CONEH), a project of Community Action Against Asthma, used a community health development approach to improve children’s asthma-related health through increasing the community’s capacity to reduce physical and social environmental triggers for asthma. Three community organizers were hired to work with community groups and residents in neighborhoods in Detroit on the priority areas of air quality, housing, and citizen involvement in the environmental project and policy decision-making. As part of the evaluation of the CONEH project, 20 one-on-one semi-structured, in-depth interviews were conducted between August and November 2005 involving steering committee members, staff members, and key community organization staff and/or community members. Using data from the evaluation of the CONEH project, this article identifies the dimensions of community capacity that were enhanced as part of a CBPR community health development approach to reducing physical and social environmental triggers associated with childhood asthma and the factors that facilitated or inhibited the enhancement of community capacity. PMID:20306137

  4. The 2010-2011 Canterbury Earthquake Sequence: Environmental effects, seismic triggering thresholds and geologic legacy

    NASA Astrophysics Data System (ADS)

    Quigley, Mark C.; Hughes, Matthew W.; Bradley, Brendon A.; van Ballegooy, Sjoerd; Reid, Catherine; Morgenroth, Justin; Horton, Travis; Duffy, Brendan; Pettinga, Jarg R.

    2016-03-01

    characteristics. However, the severity of a given environmental response at any given site related predominantly to ground shaking characteristics (PGA, peak ground velocities) and site conditions (water table depth, soil type, geomorphic and topographic setting) rather than earthquake Mw. In most cases, the most severe liquefaction, rockfall, cliff collapse, subsidence, flooding, tree damage, and biologic habitat changes were triggered by proximal, moderate magnitude (Mw ≤ 6.2) earthquakes on blind faults. CES environmental effects will be incompletely preserved in the geologic record and variably diagnostic of spatial and temporal earthquake clustering. Liquefaction feeder dikes in areas of severe and recurrent liquefaction will provide the best preserved and potentially most diagnostic CES features. Rockfall talus deposits and boulders will be well preserved and potentially diagnostic of the strong intensity of CES shaking, but challenging to decipher in terms of single versus multiple events. Most other phenomena will be transient (e.g., distal groundwater responses), not uniquely diagnostic of earthquakes (e.g., flooding), or more ambiguous (e.g. biologic changes). Preliminary palaeoseismic investigations in the CES region indicate recurrence of liquefaction in susceptible sediments of 100 to 300 yr, recurrence of severe rockfall event(s) of ca. 6000 to 8000 yr, and recurrence of surface rupturing on the largest CES source fault of ca. 20,000 to 30,000 yr. These data highlight the importance of utilising multiple proxy datasets in palaeoearthquake studies. The severity of environmental effects triggered during the strongest CES earthquakes was as great as or equivalent to any historic or prehistoric effects recorded in the geologic record. We suggest that the shaking caused by rupture of local blind faults in the CES comprised a 'worst case' seismic shaking scenario for parts of the Christchurch urban area. Moderate Mw blind fault earthquakes may contribute the highest

  5. Psychiatric Comorbidities and Environmental Triggers in Patients with Chronic Daily Headache: A Lifestyle Study

    PubMed Central

    Faizi, Fakhrudin; Tavallaee, Abbas; Rahimi, Aboulfazl; Saghafinia, Masoud

    2017-01-01

    Objective: Patients with chronic daily headache (CDH) suffer from several significant psychiatric comorbidities and have unhealthy lifestyle. We aimed at studying psychiatric comorbidities, environmental triggers, lifestyle factors, and intensity of CDH in patients referred by the department of neurology from 2011 to 2014. Method: Through medical and psychiatric interviews and using 0 to 10 visual analogue scale (VAS), we assessed patients with CDH, using a checklist, to elicit psychiatric comorbidities, intensity of CDH, environmental factors, and lifestyle derangement. Results: We interviewed 413 (age 16-80 years, mean 40 +/- 14.0) out of 548 patients; 312 (75.5%) were married, and 282 (68.1%) were female. Environmental triggers (374, 90.6%) were the most common cause of CDH, while 214 (51.8%) had no compliance to recommended nutrition. Exercise avoidance (201, 48.7%) was the less prevalent lifestyle factor. Of the patients, 372 (90.1%) were stressed and 162 (39.2%) had obsessive-compulsive disorder (OCD), which were the most and less prevalent psychiatric comorbidities, respectively. Intensity of pain was moderate to severe (mean score = 7.1+/- 1.9), while females reported higher VAS scores (p<0.02). Patients with previous history of psychotherapy reported higher score of VAS (p<0.001). Those patients living with a person suffering from head pain reported more VAS score (p<0.003). Conclusion: Notable psychiatric comorbidities were found in patients with CDH, many of which are modifiable such as environmental triggers and unhealthy lifestyle. In heavily populated cities, these factors may double the burden of the CDH by precipitating new or exacerbating previous psychiatric comorbidities. We, thus, suggest conducting more studies on this subject. PMID:28496499

  6. An alert system for triggering different levels of coastal management urgency: Tunisia case study using rapid environmental assessment data.

    PubMed

    Price, A R G; Jaoui, K; Pearson, M P; Jeudy de Grissac, A

    2014-03-15

    Rapid environmental assessment (REA) involves scoring abundances of ecosystems/species groups and magnitude of pressures, concurrently, using the same logarithmic (0-6) assessment scale. We demonstrate the utility of REA data for an alert system identifying different levels of coastal management concern. Thresholds set for abundances/magnitudes, when crossed, trigger proposed responses. Kerkennah, Tunisia, our case study, has significant natural assets (e.g. exceptional seagrass and invertebrate abundances), subjected to varying levels of disturbance and management concern. Using REA thresholds set, fishing, green algae/eutrophication and oil occurred at 'low' levels (scores 0-1): management not (currently) necessary. Construction and wood litter prevailed at 'moderate' levels (scores 2-4): management alerted for (further) monitoring. Solid waste densities were 'high' (scores 5-6): management alerted for action; quantities of rubbish were substantial (20-200 items m⁻¹ beach) but not unprecedented. REA is considered a robust methodology and complementary to other rapid assessment techniques, environmental frameworks and indicators of ecosystem condition. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. Environmental triggers of COPD symptoms: a case cross-over study.

    PubMed

    Sama, Susan R; Kriebel, David; Gore, Rebecca J; DeVries, Rebecca; Rosiello, Richard

    2017-01-01

    This study investigated the hypothesis that common environmental chemical exposures with known irritant or sensitising properties trigger exacerbations for patients with chronic obstructive pulmonary disease (COPD). We conducted a case cross-over study in 168 patients with COPD who were members of a disease management group in central Massachusetts. Participants completed a baseline health survey and several short exposure surveys. Exposure surveys were administered by a nurse when a participant telephoned to report an exacerbation (case periods) and at a maximum of three randomly identified control periods when they were not experiencing an exacerbation. We compared exposures in the week preceding an exacerbation with exposures in normal (non-exacerbation) weeks. The questionnaire assessed short-term (1 week) home, community and workplace activities and exposures that may be associated with COPD exacerbation. Self-reported exercise was negatively associated with exacerbation (OR=0.59, 95% CI: 0.35 to 1.00). Among the environmental chemical exposures, car and truck exhaust (OR=4.36, 95% CI: 1.76 to 10.80) and use of scented laundry products (OR=2.69, 95% CI: 1.31 to 5.52) showed strong positive effects. Self-reported respiratory infections were strongly associated with exacerbation (OR=7.90, 95% CI 4.29 to 14.50). Variations in outdoor temperature were associated with COPD exacerbation risk (moderate versus cold temperature OR=1.95, 95% CI 1.09 to 3.49 and warm versus cold OR=0.43, 95% CI: 0.26 to 0.70). These results suggest that some environmental chemical exposures may play a role in triggering COPD exacerbations. If confirmed, they may provide useful guidance for patients with COPD to better manage their disease.

  8. Environmental triggers of COPD symptoms: a case cross-over study

    PubMed Central

    Sama, Susan R; Kriebel, David; Gore, Rebecca J; DeVries, Rebecca; Rosiello, Richard

    2017-01-01

    Introduction This study investigated the hypothesis that common environmental chemical exposures with known irritant or sensitising properties trigger exacerbations for patients with chronic obstructive pulmonary disease (COPD). Methods We conducted a case cross-over study in 168 patients with COPD who were members of a disease management group in central Massachusetts. Participants completed a baseline health survey and several short exposure surveys. Exposure surveys were administered by a nurse when a participant telephoned to report an exacerbation (case periods) and at a maximum of three randomly identified control periods when they were not experiencing an exacerbation. We compared exposures in the week preceding an exacerbation with exposures in normal (non-exacerbation) weeks. The questionnaire assessed short-term (1 week) home, community and workplace activities and exposures that may be associated with COPD exacerbation. Results Self-reported exercise was negatively associated with exacerbation (OR=0.59, 95% CI: 0.35 to 1.00). Among the environmental chemical exposures, car and truck exhaust (OR=4.36, 95% CI: 1.76 to 10.80) and use of scented laundry products (OR=2.69, 95% CI: 1.31 to 5.52) showed strong positive effects. Self-reported respiratory infections were strongly associated with exacerbation (OR=7.90, 95% CI 4.29 to 14.50). Variations in outdoor temperature were associated with COPD exacerbation risk (moderate versus cold temperature OR=1.95, 95% CI 1.09 to 3.49 and warm versus cold OR=0.43, 95% CI: 0.26 to 0.70). Conclusions These results suggest that some environmental chemical exposures may play a role in triggering COPD exacerbations. If confirmed, they may provide useful guidance for patients with COPD to better manage their disease. PMID:29071071

  9. Alcohol withdrawal syndrome: symptom-triggered versus fixed-schedule treatment in an outpatient setting.

    PubMed

    Elholm, Bjarne; Larsen, Klaus; Hornnes, Nete; Zierau, Finn; Becker, Ulrik

    2011-01-01

    To investigate whether, in the treatment with chlordiazepoxide for outpatient alcohol withdrawal, there are advantages of symptom-triggered self-medication over a fixed-schedule regimen. A randomized controlled trial in outpatient clinics for people suffering from alcohol dependence (AD) and alcohol-related problems; 165 adult patients in an outpatient setting in a specialized alcohol treatment unit were randomized 1:1 to either a symptom-triggered self-medication or tapered dose, using chlordiazepoxide. Alcohol withdrawal symptoms, amount of medication, duration of symptoms, time to relapse and patient satisfaction were measured. Patients assessed their symptoms using the Short Alcohol Withdrawal Scale (SAWS). Patient satisfaction was monitored by the Diabetes Treatment Satisfaction Questionnaire. We used the Well-Being Index and the European addiction severity index for the 1-year follow-up. We found no differences in the quantity of medication consumed, time to relapse, well being or treatment satisfaction. Symptom-triggered self-medication was as safe as fixed-schedule medication in treating outpatients with AD and mild to moderate symptoms of AWS. The SAWS is a powerful monitoring tool, because it is brief and permits the subject to log the withdrawal symptoms.

  10. First macrobiota biomineralization was environmentally triggered

    PubMed Central

    Ivantsov, Andrey Yu

    2017-01-01

    Why large and diverse skeletons first appeared ca 550 Ma is not well understood. Many Ediacaran skeletal biota show evidence of flexibility, and bear notably thin skeletal walls with simple, non-hierarchical microstructures of either aragonite or high-Mg calcite. We present evidence that the earliest skeletal macrobiota, found only in carbonate rocks, had close soft-bodied counterparts hosted in contemporary clastic rocks. This includes the calcareous discoidal fossil Suvorovella, similar to holdfasts of Ediacaran biota taxa previously known only as casts and moulds, as well as tubular and vase-shaped fossils. In sum, these probably represent taxa of diverse affinity including unicellular eukaryotes, total group cnidarians and problematica. Our findings support the assertion that the calcification was an independent and derived feature that appeared in diverse groups where an organic scaffold was the primitive character, which provided the framework for interactions between the extracellular matrix and mineral ions. We conclude that such skeletons may have been acquired with relative ease in the highly saturated, high alkalinity carbonate settings of the Ediacaran, where carbonate polymorph was further controlled by seawater chemistry. The trigger for Ediacaran biomineralization may have been either changing seawater Mg/Ca and/or increasing oxygen levels. By the Early Cambrian, however, biomineralization styles and the range of biominerals had significantly diversified, perhaps as an escalating defensive response to increasing predation pressure. Indeed skeletal hardparts had appeared in clastic settings by Cambrian Stage 1, suggesting independence from ambient seawater chemistry where genetic and molecular mechanisms controlled biomineralization and mineralogy had become evolutionarily constrained. PMID:28356454

  11. Environmental triggers of acute myocardial infarction: results of a nationwide multiple-factorial population study.

    PubMed

    Claeys, Marc J; Coenen, Sarah; Colpaert, Charlotte; Bilcke, Joke; Beutels, Phillip; Wouters, Kristien; Legrand, Victor; Van Damme, Pierre; Vrints, Christiaan

    2015-12-01

    The objective of this study was to study the independent environmental triggers of ST-elevation myocardial infarction (STEMI) in a multifactorial environmental population model. Daily counts of all STEMI patients who underwent urgent percutaneous coronary intervention over the period 2006-2009 in Belgium were associated with average daily meteorological data and influenza-like illness incidence data. The following meteorological measures were investigated: particulate matter less than 10 μM (PM10) and less than 2.5 μM (PM(2.5)), ozone, black smoke, temperature and relative humidity. During the study period a total of 15,964 STEMI patients (mean age 63, 75% male) were admitted with a daily average admission rate of 11 ± 4 patients. A multivariate Poisson regression analysis showed that only the temperature was significantly correlated with STEMI, with an 8% increase in the risk of STEMI for each 10°C decrease in temperature (adjusted incidence risk ratio (IRR) 0.92, 95% CI 0.89-0.96). The effects of temperature were consistent among several subpopulations but the strongest effect was seen in diabetic patients (IRR 0.85, 95% CI 0.78 -0.95). There was a trend for an incremental risk of STEMI for each 10 μg/m³ PM(2.5) increase and during influenza epidemics with IRR of 1.02 (95% CI 1.00-1.04) and 1.07 (95% CI 0.98-1.16), respectively. In a global environmental model, low temperature is the most important environmental trigger for STEMI, whereas air pollution and influenza epidemics only seem to have a modest effect.

  12. Environmental setting of Maple Creek watershed, Nebraska

    USGS Publications Warehouse

    Fredrick, Brian S.; Linard, Joshua I.; Carpenter, Jennifer L.

    2006-01-01

    The Maple Creek watershed covers a 955-square-kilometer area in eastern Nebraska, which is a region dominated by agricultural land use. The Maple Creek watershed is one of seven areas currently included in a nationwide study of the sources, transport, and fate of water and chemicals in agricultural watersheds. This study, known as the topical study of 'Agricultural Chemicals: Sources, Transport, and Fate' is part of the National Water-Quality Assessment Program being conducted by the U.S. Geological Survey. The Program is designed to describe water-quality conditions and trends based on representative surface- and ground-water resources across the Nation. The objective of the Agricultural Chemicals topical study is to investigate the sources, transport, and fate of selected agricultural chemicals in a variety of agriculturally diverse environmental settings. The Maple Creek watershed was selected for the Agricultural Chemicals topical study because its watershed represents the agricultural setting that characterizes eastern Nebraska. This report describes the environmental setting of the Maple Creek watershed in the context of how agricultural practices, including agricultural chemical applications and irrigation methods, interface with natural settings and hydrologic processes. A description of the environmental setting of a subwatershed within the drainage area of Maple Creek is included to improve the understanding of the variability of hydrologic and chemical cycles at two different scales.

  13. Flexible trigger menu implementation on the Global Trigger for the CMS Level-1 trigger upgrade

    NASA Astrophysics Data System (ADS)

    MATSUSHITA, Takashi; CMS Collaboration

    2017-10-01

    The CMS experiment at the Large Hadron Collider (LHC) has continued to explore physics at the high-energy frontier in 2016. The integrated luminosity delivered by the LHC in 2016 was 41 fb-1 with a peak luminosity of 1.5 × 1034 cm-2s-1 and peak mean pile-up of about 50, all exceeding the initial estimations for 2016. The CMS experiment has upgraded its hardware-based Level-1 trigger system to maintain its performance for new physics searches and precision measurements at high luminosities. The Global Trigger is the final step of the CMS Level-1 trigger and implements a trigger menu, a set of selection requirements applied to the final list of objects from calorimeter and muon triggers, for reducing the 40 MHz collision rate to 100 kHz. The Global Trigger has been upgraded with state-of-the-art FPGA processors on Advanced Mezzanine Cards with optical links running at 10 GHz in a MicroTCA crate. The powerful processing resources of the upgraded system enable implementation of more algorithms at a time than previously possible, allowing CMS to be more flexible in how it handles the available trigger bandwidth. Algorithms for a trigger menu, including topological requirements on multi-objects, can be realised in the Global Trigger using the newly developed trigger menu specification grammar. Analysis-like trigger algorithms can be represented in an intuitive manner and the algorithms are translated to corresponding VHDL code blocks to build a firmware. The grammar can be extended in future as the needs arise. The experience of implementing trigger menus on the upgraded Global Trigger system will be presented.

  14. Setting the Delay of the LTD Switch Firing Using Trigger Inductors

    NASA Astrophysics Data System (ADS)

    Alexeenko, V. M.; Sinebryukhov, V. A.; Kondratiev, S. S.; Volkov, S. N.; Kim, A. A.; Yakovlev, V. Yu.

    2018-01-01

    Simulation results are compared with experimental data to define the integral breakdown criterion for the spark gaps of the switches of the LTDs with oil insulation and to determine the influence of the inductance of the trigger inductor on the delay of the switch firing. The results confirm that the shape of the output square pulse produced by the oil-insulated LTDs can be corrected as required if the trigger inductors are used to trigger the cavity switches.

  15. The outdoor air quality flag program in central California: a school-based educational intervention to potentially help reduce children's exposure to environmental asthma triggers.

    PubMed

    Shendell, Derek G; Rawling, Mary-Michal; Foster, Christine; Bohlke, Alicia; Edwards, Bobbie; Rico, Susie A; Felix, Justina; Eaton, Sandra; Moen, Stephanie; Roberts, Eric M; Love, Mary Beth

    2007-10-01

    This paper describes a novel school-based, visual environmental public health educational intervention intended to help reduce the exposure of children-and adults-to outdoor air pollution, including known environmental asthma triggers like ozone and particles. The overarching goal was to enhance the learning, recreational, and work environments of students and staff. The specific purpose of the Asthma-Friendly Outdoor (Ambient) Air Quality Flag Program was to establish an education and communication tool for Central California communities that would accomplish two things: (1) Establish permanent local policy change to existing operating procedures in school districts and schools to help reduce the exposure of students, teachers, staff, and nearby communities to outdoor environmental asthma triggers and (2) provide education on air quality and potential health effects of exposure to air pollutants. Data on the program from its initial years are presented. To date, the following important lessons have been learned: (1) Science-based, simple, visual, low-cost school-based educational interventions to help reduce human exposure to outdoor environmental asthma triggers (i.e., ozone, particles, and pollens) can work in socioeconomically and ethnically diverse urban and rural or agricultural communities, and (2) local health and environmental justice groups such as asthma coalitions can successfully lead school-based environmental interventions to help improve children's quality of life.

  16. Feasibility of Deploying Inhaler Sensors to Identify the Impacts of Environmental Triggers and Built Environment Factors on Asthma Short-Acting Bronchodilator Use.

    PubMed

    Su, Jason G; Barrett, Meredith A; Henderson, Kelly; Humblet, Olivier; Smith, Ted; Sublett, James W; Nesbitt, LaQuandra; Hogg, Chris; Van Sickle, David; Sublett, James L

    2017-02-01

    Epidemiological asthma research has relied upon self-reported symptoms or healthcare utilization data, and used the residential address as the primary location for exposure. These data sources can be temporally limited, spatially aggregated, subjective, and burdensome for the patient to collect. First, we aimed to test the feasibility of collecting rescue inhaler use data in space-time using electronic sensors. Second, we aimed to evaluate whether these data have the potential to identify environmental triggers and built environment factors associated with rescue inhaler use and to determine whether these findings would be consistent with the existing literature. We utilized zero-truncated negative binomial models to identify triggers associated with inhaler use, and implemented three sensitivity analyses to validate our findings. Electronic sensors fitted on metered dose inhalers tracked 5,660 rescue inhaler use events in space and time for 140 participants from 13 June 2012 to 28 February 2014. We found that the inhaler sensors were feasible in passively collecting objective rescue inhaler use data. We identified several environmental triggers with a positive and significant association with inhaler use, including: AQI, PM10, weed pollen, and mold. Conversely, the spatial distribution of tree cover demonstrated a negative and significant association with inhaler use. Utilizing a sensor to capture the signal of rescue inhaler use in space-time offered a passive and objective signal of asthma activity. This approach enabled detailed analyses to identify environmental triggers and built environment factors that are associated with asthma symptoms beyond the residential address. The application of these new technologies has the potential to improve our surveillance and understanding of asthma. Citation: Su JG, Barrett MA, Henderson K, Humblet O, Smith T, Sublett JW, Nesbitt L, Hogg C, Van Sickle D, Sublett JL. 2017. Feasibility of deploying inhaler sensors to

  17. Environmental History Modulates Arabidopsis Pattern-Triggered Immunity in a HISTONE ACETYLTRANSFERASE1-Dependent Manner.

    PubMed

    Singh, Prashant; Yekondi, Shweta; Chen, Po-Wen; Tsai, Chia-Hong; Yu, Chun-Wei; Wu, Keqiang; Zimmerli, Laurent

    2014-06-01

    In nature, plants are exposed to a fluctuating environment, and individuals exposed to contrasting environmental factors develop different environmental histories. Whether different environmental histories alter plant responses to a current stress remains elusive. Here, we show that environmental history modulates the plant response to microbial pathogens. Arabidopsis thaliana plants exposed to repetitive heat, cold, or salt stress were more resistant to virulent bacteria than Arabidopsis grown in a more stable environment. By contrast, long-term exposure to heat, cold, or exposure to high concentrations of NaCl did not provide enhanced protection against bacteria. Enhanced resistance occurred with priming of Arabidopsis pattern-triggered immunity (PTI)-responsive genes and the potentiation of PTI-mediated callose deposition. In repetitively stress-challenged Arabidopsis, PTI-responsive genes showed enrichment for epigenetic marks associated with transcriptional activation. Upon bacterial infection, enrichment of RNA polymerase II at primed PTI marker genes was observed in environmentally challenged Arabidopsis. Finally, repetitively stress-challenged histone acetyltransferase1-1 (hac1-1) mutants failed to demonstrate enhanced resistance to bacteria, priming of PTI, and increased open chromatin states. These findings reveal that environmental history shapes the plant response to bacteria through the development of a HAC1-dependent epigenetic mark characteristic of a primed PTI response, demonstrating a mechanistic link between the primed state in plants and epigenetics. © 2014 American Society of Plant Biologists. All rights reserved.

  18. Allergens in School Settings: Results of Environmental Assessments in 3 City School Systems

    ERIC Educational Resources Information Center

    Abramson, Stuart L.; Turner-Henson, Anne; Anderson, Lise; Hemstreet, Mary P.; Bartholomew, L. Kay; Joseph, Christine L. M.; Tang, Shenghui; Tyrrell, Shellie; Clark, Noreen M.; Ownby, Dennis

    2006-01-01

    Environmental allergens are major triggers for pediatric asthma. While children's greatest exposure to indoor allergens is in the home, other public places where children spend a large amount of time, such as school and day care centers, may also be sources of significant allergen encounters. The purpose of this article is to describe schoolroom…

  19. The CMS High-Level Trigger and Trigger Menus

    NASA Astrophysics Data System (ADS)

    Avetisyan, Aram

    2008-04-01

    The CMS experiment is one of the two general-purpose experiments due to start operation soon at the Large Hadron Collider (LHC). The LHC will collide protons at a centre of mass energy of 14 TeV, with a bunch-crossing rate of 40 MHz. The online event selection for the CMS experiment is carried out in two distinct stages. At Level-1 the trigger electronics reduces the 40 MHz collision rate to provide up to 100 kHz of interesting events, based on objects found using its calorimeter and muon subsystems. The High Level Trigger (HLT) that runs in the Filter Farm of the CMS experiment is a set of sophisticated software tools that run in a real-time environment to make a further selection and archive few hundred Hz of interesting events. The coherent tuning of the HLT algorithms to accommodate multiple physics channels is a key issue for CMS, one that literally defines the reach of the experiment's physics program. In this presentation we will discuss the strategies and trigger configuration developed for startup physics program of the CMS experiment, up to a luminosity of 10^31 s-1cm-2. Emphasis will be given to the full trigger menus, including physics and calibration triggers.

  20. Small-area distribution of multiple sclerosis incidence in western France: in search of environmental triggers.

    PubMed

    Hammas, Karima; Yaouanq, Jacqueline; Lannes, Morgane; Edan, Gilles; Viel, Jean-François

    2017-09-21

    Despite intensive research over several decades, the etiology of multiple sclerosis (MS) remains poorly understood, although environmental factors are supposedly implicated. Our goal was to identify spatial clusters of MS incident cases at the small-area level to provide clues to local environmental risk factors that might cause or trigger the disease. A population-based and multi-stage study was performed in the French Brittany region to accurately ascertain the clinical onset of disease during the 2000-2004 period. The municipality of residence at the time of clinical onset was geocoded. To test for the presence of MS incidence clusters and to identify their approximate locations, we used a spatial scan statistic. We adjusted for socioeconomic deprivation, known to be strongly associated with increased MS incident rates, and scanned simultaneously for areas with either high or low rates. Sensitivity analyses (focusing on relapsing-remitting forms and/or places of residence available within the year following clinical onset) were performed. A total of 848 incident cases of MS were registered in Brittany, corresponding to a crude annual incidence rate of 5.8 per 100,000 inhabitants. The spatial scan statistic did not find a significant cluster of MS incidence in either the primary analysis (p value ≥ 0.56) or in the sensitivity analyses (p value ≥ 0.16). The findings of this study indicate that MS incidence is not markedly affected across space, suggesting that in the years preceding the first clinical expression of the disease, no environmental trigger is operative at the small-area population level in the French Brittany region.

  1. Smart trigger logic for focal plane arrays

    DOEpatents

    Levy, James E; Campbell, David V; Holmes, Michael L; Lovejoy, Robert; Wojciechowski, Kenneth; Kay, Randolph R; Cavanaugh, William S; Gurrieri, Thomas M

    2014-03-25

    An electronic device includes a memory configured to receive data representing light intensity values from pixels in a focal plane array and a processor that analyzes the received data to determine which light values correspond to triggered pixels, where the triggered pixels are those pixels that meet a predefined set of criteria, and determines, for each triggered pixel, a set of neighbor pixels for which light intensity values are to be stored. The electronic device also includes a buffer that temporarily stores light intensity values for at least one previously processed row of pixels, so that when a triggered pixel is identified in a current row, light intensity values for the neighbor pixels in the previously processed row and for the triggered pixel are persistently stored, as well as a data transmitter that transmits the persistently stored light intensity values for the triggered and neighbor pixels to a data receiver.

  2. Tidal triggering of moonquakes.

    NASA Technical Reports Server (NTRS)

    Hamilton, W. L.

    1972-01-01

    It is argued that the moonquakes recorded by sensors at the Apollo 12 landing site between December 1969 and December 1970, and which according to Latham et al. (1971) are believed to be triggered by the anomalistic lunar tide, could be triggered just as well by the latitudinal (or declination) tidal wave. Considerations are set forth which indicate that a combined latitudinal-anomalistic tidal mechanism is supported by Latham's data.

  3. Headache triggers in the US military.

    PubMed

    Theeler, Brett J; Kenney, Kimbra; Prokhorenko, Olga A; Fideli, Ulgen S; Campbell, William; Erickson, Jay C

    2010-05-01

    Headaches can be triggered by a variety of factors. Military service members have a high prevalence of headache but the factors triggering headaches in military troops have not been identified. The objective of this study is to determine headache triggers in soldiers and military beneficiaries seeking specialty care for headaches. A total of 172 consecutive US Army soldiers and military dependents (civilians) evaluated at the headache clinics of 2 US Army Medical Centers completed a standardized questionnaire about their headache triggers. A total of 150 (87%) patients were active-duty military members and 22 (13%) patients were civilians. In total, 77% of subjects had migraine; 89% of patients reported at least one headache trigger with a mean of 8.3 triggers per patient. A wide variety of headache triggers was seen with the most common categories being environmental factors (74%), stress (67%), consumption-related factors (60%), and fatigue-related factors (57%). The types of headache triggers identified in active-duty service members were similar to those seen in civilians. Stress-related triggers were significantly more common in soldiers. There were no significant differences in trigger types between soldiers with and without a history of head trauma. Headaches in military service members are triggered mostly by the same factors as in civilians with stress being the most common trigger. Knowledge of headache triggers may be useful for developing strategies that reduce headache occurrence in the military.

  4. Acute exposure to high environmental ammonia (HEA) triggers the emersion response in the green shore crab.

    PubMed

    Zimmer, Alex M; Wood, Chris M

    2017-02-01

    The physiological effects of high environmental ammonia (HEA) exposure have been well documented in many aquatic species. In particular, it has recently been demonstrated that exposure to ammonia in fish leads to a similar hyperventilatory response as observed during exposure to hypoxia. In littoral crabs, such as the green crab (Carcinus maenas), exposure to severe hypoxia triggers an emersion response whereby crabs escape hypoxia to breathe air. We hypothesized that exposure to HEA in green crabs would lead to a similar behavioural response which is specific to ammonia. Using an experimental arena containing a rock bed onto which crabs could emerse, we established that exposure to HEA (4mmol/l NH 4 HCO 3 ) for 15min triggers emersion in crabs. In experiments utilizing NaHCO 3 controls and NH 4 HCO 3 injections, we further determined that emersion was triggered specifically by external ammonia and was independent of secondary acid-base or respiratory disturbances caused by HEA. We then hypothesized that emersion from HEA provides a physiological benefit, similar to emersion from hypoxia. Exposure to 15min of HEA without emersion (no rock bed present) caused significant increases in arterial haemolymph total ammonia (T amm ), pH, and [HCO 3 - ] . When emersion was allowed, arterial haemolymph T amm and [HCO 3 - ] increased, but no alkalosis developed. Moreover, emersion decreased haemolymph partial pressure of NH 3 relative to crabs which could not emerse. Overall, we demonstrate a novel behavioural response to HEA exposure in crabs which we propose may share similar mechanistic pathways with the emersion response triggered by hypoxia. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Recent advances in environmental controls outside the home setting.

    PubMed

    Hauptman, Marissa; Phipatanakul, Wanda

    2016-04-01

    It has been well studied that aeroallergen, mold, and airborne pollutant exposure in the inner-city home environment is associated with significant childhood asthma morbidity. Although the home environment has been extensively studied, the school environment is less well understood. In this article, we discuss the relationship between environmental exposures within the school and daycare environment and pediatric asthma morbidity and novel environmental interventions designed to help mitigate pediatric asthma morbidity. Studies assessing environmental exposures outside the home environment and interventions to mitigate these exposures have the potential to reduce pediatric asthma morbidity. Further study in this area should focus on the complex cost benefit analyses of environmental interventions outside the home setting, while controlling for the home environment.

  6. Antiviral immune responses: triggers of or triggered by autoimmunity?

    PubMed Central

    Münz, Christian; Lünemann, Jan D.; Getts, Meghann Teague; Miller, Stephen D.

    2010-01-01

    Several common autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus (SLE) and multiple sclerosis, are genetically linked to distinct human MHC class II molecules and other immune modulators. However, genetic predisposition is only one risk factor for the development of these diseases, and low concordance rates in monozygotic twins as well as geographical distribution of disease risk point towards environmental factors in the genesis of these diseases. Among these environmental factors, infections have been implicated in the onset and/or promotion of autoimmunity. In this review, we outline mechanisms by which pathogens can trigger autoimmune disease, and also pathways by which infection and immune control of infectious disease might be dysregulated during autoimmunity. PMID:19319143

  7. Nanoengineered surfaces for focal adhesion guidance trigger mesenchymal stem cell self-organization and tenogenesis.

    PubMed

    Iannone, Maria; Ventre, Maurizio; Formisano, Lucia; Casalino, Laura; Patriarca, Eduardo J; Netti, Paolo A

    2015-03-11

    The initial conditions for morphogenesis trigger a cascade of events that ultimately dictate structure and functions of tissues and organs. Here we report that surface nanopatterning can control the initial assembly of focal adhesions, hence guiding human mesenchymal stem cells (hMSCs) through the process of self-organization and differentiation. This process self-sustains, leading to the development of macroscopic tissues with molecular profiles and microarchitecture reminiscent of embryonic tendons. Therefore, material surfaces can be in principle engineered to set off the hMSC program toward tissuegenesis in a deterministic manner by providing adequate sets of initial environmental conditions.

  8. Remotely triggered earthquakes following moderate main shocks

    USGS Publications Warehouse

    Hough, S.E.

    2007-01-01

    Since 1992, remotely triggered earthquakes have been identified following large (M > 7) earthquakes in California as well as in other regions. These events, which occur at much greater distances than classic aftershocks, occur predominantly in active geothermal or volcanic regions, leading to theories that the earthquakes are triggered when passing seismic waves cause disruptions in magmatic or other fluid systems. In this paper, I focus on observations of remotely triggered earthquakes following moderate main shocks in diverse tectonic settings. I summarize evidence that remotely triggered earthquakes occur commonly in mid-continent and collisional zones. This evidence is derived from analysis of both historic earthquake sequences and from instrumentally recorded M5-6 earthquakes in eastern Canada. The latter analysis suggests that, while remotely triggered earthquakes do not occur pervasively following moderate earthquakes in eastern North America, a low level of triggering often does occur at distances beyond conventional aftershock zones. The inferred triggered events occur at the distances at which SmS waves are known to significantly increase ground motions. A similar result was found for 28 recent M5.3-7.1 earthquakes in California. In California, seismicity is found to increase on average to a distance of at least 200 km following moderate main shocks. This supports the conclusion that, even at distances of ???100 km, dynamic stress changes control the occurrence of triggered events. There are two explanations that can account for the occurrence of remotely triggered earthquakes in intraplate settings: (1) they occur at local zones of weakness, or (2) they occur in zones of local stress concentration. ?? 2007 The Geological Society of America.

  9. Development of a direct observation Measure of Environmental Qualities of Activity Settings.

    PubMed

    King, Gillian; Rigby, Patty; Batorowicz, Beata; McMain-Klein, Margot; Petrenchik, Theresa; Thompson, Laura; Gibson, Michelle

    2014-08-01

    The aim of this study was to develop an observer-rated measure of aesthetic, physical, social, and opportunity-related qualities of leisure activity settings for young people (with or without disabilities). Eighty questionnaires were completed by sets of raters who independently rated 22 community/home activity settings. The scales of the 32-item Measure of Environmental Qualities of Activity Settings (MEQAS; Opportunities for Social Activities, Opportunities for Physical Activities, Pleasant Physical Environment, Opportunities for Choice, Opportunities for Personal Growth, and Opportunities to Interact with Adults) were determined using principal components analyses. Test-retest reliability was determined for eight activity settings, rated twice (4-6wk interval) by a trained rater. The factor structure accounted for 80% of the variance. The Kaiser-Meyer-Olkin Measure of Sampling Adequacy was 0.73. Cronbach's alphas for the scales ranged from 0.76 to 0.96, and interrater reliabilities (ICCs) ranged from 0.60 to 0.93. Test-retest reliabilities ranged from 0.70 to 0.90. Results suggest that the MEQAS has a sound factor structure and preliminary evidence of internal consistency, interrater, and test-retest reliability. The MEQAS is the first observer-completed measure of environmental qualities of activity settings. The MEQAS allows researchers to assess comprehensively qualities and affordances of activity settings, and can be used to design and assess environmental qualities of programs for young people. © 2014 Mac Keith Press.

  10. Environmental Indicators. A Preliminary Set = Indicateurs d'environnement. Une etude pilote.

    ERIC Educational Resources Information Center

    Organisation for Economic Cooperation and Development, Paris (France).

    This document provides a preliminary set of environmental indicators by which to measure environmental performance. The indicators are patterned on the outline of the Organisation for Economic Cooperation and Development (OECD) "Report on the State of the Environment," a companion volume published in the same year. This volume is…

  11. Event-triggered attitude control of spacecraft

    NASA Astrophysics Data System (ADS)

    Wu, Baolin; Shen, Qiang; Cao, Xibin

    2018-02-01

    The problem of spacecraft attitude stabilization control system with limited communication and external disturbances is investigated based on an event-triggered control scheme. In the proposed scheme, information of attitude and control torque only need to be transmitted at some discrete triggered times when a defined measurement error exceeds a state-dependent threshold. The proposed control scheme not only guarantees that spacecraft attitude control errors converge toward a small invariant set containing the origin, but also ensures that there is no accumulation of triggering instants. The performance of the proposed control scheme is demonstrated through numerical simulation.

  12. A set of nutrient limitations trigger yeast cell death in a nitrogen-dependent manner during wine alcoholic fermentation

    PubMed Central

    Duc, Camille; Pradal, Martine; Sanchez, Isabelle; Noble, Jessica; Tesnière, Catherine

    2017-01-01

    Yeast cell death can occur during wine alcoholic fermentation. It is generally considered to result from ethanol stress that impacts membrane integrity. This cell death mainly occurs when grape musts processing reduces lipid availability, resulting in weaker membrane resistance to ethanol. However the mechanisms underlying cell death in these conditions remain unclear. We examined cell death occurrence considering yeast cells ability to elicit an appropriate response to a given nutrient limitation and thus survive starvation. We show here that a set of micronutrients (oleic acid, ergosterol, pantothenic acid and nicotinic acid) in low, growth-restricting concentrations trigger cell death in alcoholic fermentation when nitrogen level is high. We provide evidence that nitrogen signaling is involved in cell death and that either SCH9 deletion or Tor inhibition prevent cell death in several types of micronutrient limitation. Under such limitations, yeast cells fail to acquire any stress resistance and are unable to store glycogen. Unexpectedly, transcriptome analyses did not reveal any major changes in stress genes expression, suggesting that post-transcriptional events critical for stress response were not triggered by micronutrient starvation. Our data point to the fact that yeast cell death results from yeast inability to trigger an appropriate stress response under some conditions of nutrient limitations most likely not encountered by yeast in the wild. Our conclusions provide a novel frame for considering both cell death and the management of nutrients during alcoholic fermentation. PMID:28922393

  13. Outdoor environmental assessment of attention promoting settings for preschool children.

    PubMed

    Mårtensson, F; Boldemann, C; Söderström, M; Blennow, M; Englund, J-E; Grahn, P

    2009-12-01

    The restorative potential of green outdoor environments for children in preschool settings was investigated by measuring the attention of children playing in settings with different environmental features. Eleven preschools with outdoor environments typical for the Stockholm area were assessed using the outdoor play environment categories (OPEC) and the fraction of visible sky from play structures (sky view factor), and 198 children, aged 4.5-6.5 years, were rated by the staff for inattentive, hyperactive and impulsive behaviors with the ECADDES tool. Children playing in large and integrated outdoor areas containing large areas of trees, shrubbery and a hilly terrain showed less often behaviors of inattention (p<.05). The choice of tool for assessment of attention is discussed in relation to outdoor stay and play characteristics in Swedish preschool settings. The results indicate that the restorative potential of green outdoor environments applies also to preschool children and that environmental assessment tools as OPEC can be useful when to locate and develop health-promoting land adjacent to preschools.

  14. Acute triggers of myocardial infarction: A case-crossover study.

    PubMed

    Ghiasmand, Maryam; Moghadamnia, Mohammad Taghi; Pourshaikhian, Majid; Kazemnejad Lili, Ehsan

    2017-12-01

    Acute myocardial infarction (AMI) is one of the most preventable non-communicable diseases in human. Identifying triggers of myocardial infarction (MI) and prevention ways of exposure-induced complications can reduce morbidity and mortality in people at risk. The aim of this study was to identify the emotional, environmental, physical and chemical dimensions of acute triggers in patients with AMI. This case-crossover study was conducted on 269 patients with AMI, hospitalized at two remedial centers in Rasht in 2015. The study samples were selected by convenient sampling method. Data were collected using researcher-made questionnaire through interviews. Hazard and control periods for each trigger and its effects on the development of MI were studied. The collected data were analyzed using descriptive and analytical statistical methods, Cochran test, and generalized estimating equation (GEE) model with logistics function default in SPSS version 21, and p  < 0.05 was considered statistically significant. The results showed that quarrel ( P  = 0.008, OR = 2.01) and hearing the sudden news ( P  = 0.001, OR = 2.19) were the most common emotional triggers. Respiratory infections ( P  = 0.0001, OR = 6.78) and exposure to hot or cold weather ( P  = 0.005, OR = 2.19) were the most frequent environmental triggers. Doing heavy activities ( P  = 0.005, OR = 1.66) and sexual activities ( P  = 0.003, OR = 2.36) were among the most common physical triggers. High-fat foods consumption and overeating ( P  = 0.0001, OR = 3.79) were the most frequent chemical triggers of AMI. It seems that given the importance of the triggers in the incidence of AMI, planning is necessary to train vulnerable individuals to reduce exposure to triggers.

  15. Environmental setting of the upper Illinois River basin and implications for water quality

    USGS Publications Warehouse

    Arnold, Terri L.; Sullivan, Daniel J.; Harris, Mitchell A.; Fitzpatrick, Faith A.; Scudder, Barbara C.; Ruhl, Peter M.; Hanchar, Dorothea W.; Stewart, Jana S.

    1999-01-01

    The upper Illinois River Basin (UIRB) is the 10,949 square mile drainage area upstream from Ottawa, Illinois, on the Illinois River. The UIRB is one of 13 studies that began in 1996 as part of the U.S. Geological Survey?s National Water- Quality Assessment program. A compilation of environmental data from Federal, State, and local agencies provides a description of the environmental setting of the UIRB. Environmental data include natural factors such as bedrock geology, physiography and surficial geology, soils, vegetation, climate, and ecoregions; and human factors such as land use, urbanization trends, and population change. Characterization of the environmental setting is useful for understanding the physical, chemical, and biological characteristics of surface and ground water in the UIRB and the possible implications of that environmental setting for water quality. Some of the possible implications identified include depletion of dissolved oxygen because of high concentrations of organic matter in wastewater, increased flooding because of suburbanization, elevated arsenic concentrations in ground water because of weathering of shale bedrock, and decreasing ground-water levels because of heavy pumping of water from the bedrock aquifers.

  16. [Comparison of the "Trigger" tool with the minimum basic data set for detecting adverse events in general surgery].

    PubMed

    Pérez Zapata, A I; Gutiérrez Samaniego, M; Rodríguez Cuéllar, E; Gómez de la Cámara, A; Ruiz López, P

    Surgery is a high risk for the occurrence of adverse events (AE). The main objective of this study is to compare the effectiveness of the Trigger tool with the Hospital National Health System registration of Discharges, the minimum basic data set (MBDS), in detecting adverse events in patients admitted to General Surgery and undergoing surgery. Observational and descriptive retrospective study of patients admitted to general surgery of a tertiary hospital, and undergoing surgery in 2012. The identification of adverse events was made by reviewing the medical records, using an adaptation of "Global Trigger Tool" methodology, as well as the (MBDS) registered on the same patients. Once the AE were identified, they were classified according to damage and to the extent to which these could have been avoided. The area under the curve (ROC) were used to determine the discriminatory power of the tools. The Hanley and Mcneil test was used to compare both tools. AE prevalence was 36.8%. The TT detected 89.9% of all AE, while the MBDS detected 28.48%. The TT provides more information on the nature and characteristics of the AE. The area under the curve was 0.89 for the TT and 0.66 for the MBDS. These differences were statistically significant (P<.001). The Trigger tool detects three times more adverse events than the MBDS registry. The prevalence of adverse events in General Surgery is higher than that estimated in other studies. Copyright © 2017 SECA. Publicado por Elsevier España, S.L.U. All rights reserved.

  17. A risk-informed decision framework for setting environmental windows for dredging projects.

    PubMed

    Suedel, Burton C; Kim, Jongbum; Clarke, Douglas G; Linkov, Igor

    2008-09-15

    Sediment dredging is necessary to sustain navigation infrastructure in ports and harbor areas. In the United States alone between 250 and 300 million cubic yards of sediment are dredged annually. Dredging activities may cause stress on aquatic biota by locally increasing turbidity and suspended sediment concentrations, physically disturbing habitat by elevated sedimentation rates, interfering in migratory behaviors, and hydraulically entraining bottom dwelling organisms. Environmental windows are a management practice used to alleviate such stresses on resident and transient biota by placing temporal restrictions on the conduct of dredging operations. Adherence to environmental windows can significantly inflate costs for project sponsors and local stakeholders. Since their inception following passage of NEPA in 1969 the process for setting environmental windows has not followed structured procedures and represents an example of the difficulty inherent in achieving a balance between biological resource protection and cost-effective construction and maintenance of navigation infrastructure. Recent developments in the fields of risk assessment for non-chemical stressors as well as experience in implementing structured risk-informed decision-making tools for sediment and natural resource management are summarized in this paper in relation to setting environmental windows. Combining risk assessment and multi-criteria decision analysis allows development of a framework for an objective process consistent with recommendations by the National Academy of Sciences for setting environmental windows. A hypothetical application of the framework for protection of Pacific herring (Clupea pallasii) in San Francisco Bay is discussed.

  18. Method for modifying trigger level for adsorber regeneration

    DOEpatents

    Ruth, Michael J.; Cunningham, Michael J.

    2010-05-25

    A method for modifying a NO.sub.x adsorber regeneration triggering variable. Engine operating conditions are monitored until the regeneration triggering variable is met. The adsorber is regenerated and the adsorbtion efficiency of the adsorber is subsequently determined. The regeneration triggering variable is modified to correspond with the decline in adsorber efficiency. The adsorber efficiency may be determined using an empirically predetermined set of values or by using a pair of oxygen sensors to determine the oxygen response delay across the sensors.

  19. Stability of Playfulness across Environmental Settings: A Pilot Study

    ERIC Educational Resources Information Center

    Rigby, Patricia; Gaik, Sandy

    2007-01-01

    The Test of Playfulness (ToP) was used in this pilot study to examine the stability of playfulness of 16 children with cerebral palsy (CP), aged 4-8 years, across three environmental settings: home, community, and school. Each videotaped play segment was scored using the ToP. The ANOVA statistic demonstrated a significant variance (p less than…

  20. 1. ENVIRONMENTAL SETTING FROM SOUTH EAST CORNER OF BRIGHTON DAM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. ENVIRONMENTAL SETTING FROM SOUTH EAST CORNER OF BRIGHTON DAM ROAD AND NEW HAMPSHIRE AVENUE, SHOWING SOUTH (FRONT) AND EAST SIDE, WITH ST. LUKE'S EPISCOPAL CHURCH IN BACKGROUND - Brighton Grange Hall, 263 Brighton Dam Road at New Hampshire Avenue, Brighton, Montgomery County, MD

  1. Proposal of a trigger tool to assess adverse events in dental care.

    PubMed

    Corrêa, Claudia Dolores Trierweiler Sampaio de Oliveira; Mendes, Walter

    2017-11-21

    The aim of this study was to propose a trigger tool for research of adverse events in outpatient dentistry in Brazil. The tool was elaborated in two stages: (i) to build a preliminary set of triggers, a literature review was conducted to identify the composition of trigger tools used in other areas of health and the principal adverse events found in dentistry; (ii) to validate the preliminarily constructed triggers a panel of experts was organized using the modified Delphi method. Fourteen triggers were elaborated in a tool with explicit criteria to identify potential adverse events in dental care, essential for retrospective patient chart reviews. Studies on patient safety in dental care are still incipient when compared to other areas of health care. This study intended to contribute to the research in this field. The contribution by the literature and guidance from the expert panel allowed elaborating a set of triggers to detect adverse events in dental care, but additional studies are needed to test the instrument's validity.

  2. Triggers of Eating in Everyday Life

    PubMed Central

    Tomiyama, A. Janet; Mann, Traci; Comer, Lisa

    2009-01-01

    Understanding the triggers of eating in everyday life is crucial for the creation of interventions to promote healthy eating and to prevent overeating. Here, the proximal predictors of eating are explored in a natural setting. Research from laboratory settings suggests that restrained eaters overeat after experiencing anxiety, distraction, and the presence of positive or negative moods, but not hunger; whereas the only factor that triggers eating in unrestrained eaters is hunger. In this study, 137 female participants reported hourly for two days on these potential predictors and their eating using electronic diaries, allowing us to establish the relationships between these factors while participants went about their normal daily activities. The main outcome variables were the number of servings eaten and whether or not food was eaten. Contrary to findings from laboratory settings, in everyday life restrained eaters (1) did not overeat in response to anxiety; (2) ate less in the presence of positive or negative moods; and (3) ate more in response to hunger. The relationships between these factors and eating among unrestrained eaters were closer to those found in laboratory settings. In conclusion, predictors of eating must be studied in everyday life to develop successful interventions. PMID:18773931

  3. Low-power triggered data acquisition system and method

    NASA Technical Reports Server (NTRS)

    Champaigne, Kevin (Inventor); Sumners, Jonathan (Inventor)

    2012-01-01

    A low-power triggered data acquisition system and method utilizes low-powered circuitry, comparators, and digital logic incorporated into a miniaturized device interfaced with self-generating transducer sensor inputs to detect, identify and assess impact and damage to surfaces and structures wherein, upon the occurrence of a triggering event that produces a signal greater than a set threshold changes the comparator output and causes the system to acquire and store digital data representative of the incoming waveform on at least one triggered channel. The sensors may be disposed in an array to provide triangulation and location of the impact.

  4. Recognising triggers for soft-sediment deformation: Current understanding and future directions

    NASA Astrophysics Data System (ADS)

    Owen, Geraint; Moretti, Massimo; Alfaro, Pedro

    2011-04-01

    Most of the 16 papers in this special issue were presented at a session entitled "The recognition of trigger mechanisms for soft-sediment deformation" at the 27th IAS Meeting of Sedimentology in Alghero, Sardinia, Italy, which took place from 20th-23rd September 2009. They describe soft-sediment deformation structures that range widely in morphology, age, depositional environment and tectonic setting. In their interpretations, the authors have been asked to focus on identifying the agent that triggered deformation. Our aims in this introductory overview are to: (1) review the definition and scope of soft-sediment deformation; (2) clarify the significance and role of the trigger; (3) set the contributions in context and summarise their findings; and (4) discuss strategies for reliably identifying triggers and make recommendations for future study of this widespread and significant category of sedimentary structures. We recommend a three-stage approach to trigger recognition, combining the assessment of facies, potential triggers, and available criteria. This focus on the trigger for deformation distinguishes this collection of papers on soft-sediment deformation from other important collections, notably those edited by Jones and Preston (1987), Maltman (1994), Maltman et al. (2000), Shiki et al. (2000), Ettensohn et al. (2002b), Van Rensbergen et al. (2003) and Storti and Vannucchi (2007).

  5. Transformative environmental governance

    USGS Publications Warehouse

    Chaffin, Brian C.; Garmestani, Ahjond S.; Gunderson, Lance H.; Harm Benson, Melinda; Angeler, David G.; Arnold, Craig Anthony (Tony); Cosens, Barbara; Kundis Craig, Robin; Ruhl, J.B.; Allen, Craig R.

    2016-01-01

    Transformative governance is an approach to environmental governance that has the capacity to respond to, manage, and trigger regime shifts in coupled social-ecological systems (SESs) at multiple scales. The goal of transformative governance is to actively shift degraded SESs to alternative, more desirable, or more functional regimes by altering the structures and processes that define the system. Transformative governance is rooted in ecological theories to explain cross-scale dynamics in complex systems, as well as social theories of change, innovation, and technological transformation. Similar to adaptive governance, transformative governance involves a broad set of governance components, but requires additional capacity to foster new social-ecological regimes including increased risk tolerance, significant systemic investment, and restructured economies and power relations. Transformative governance has the potential to actively respond to regime shifts triggered by climate change, and thus future research should focus on identifying system drivers and leading indicators associated with social-ecological thresholds.

  6. Stability of playfulness across environmental settings: a pilot study.

    PubMed

    Rigby, Patricia; Gaik, Sandy

    2007-01-01

    The Test of Playfulness (ToP) was used in this pilot study to examine the stability of playfulness of 16 children with cerebral palsy (CP), aged 4-8 years, across three environmental settings: home, community, and school. Each videotaped play segment was scored using the ToP. The ANOVA statistic demonstrated a significant variance (p < 0.05) in the playfulness of the children across the 3 settings. The children were most playful at home and least playful at school (p < 0.05). The variability in playfulness across settings suggests that playful behaviors are influenced by factors external to the child. Eleven children were playful (achieving a positive ToP score) in at least one environment, which demonstrates that they had the capacity to be playful. Their play was supported in some settings and not in others. However, there was a lack of playfulness in 65% of the play segments suggesting that these children experience many barriers to their participation in play. Future research is needed to identify factors that help and hinder the playfulness of children with CP.

  7. 77 FR 1501 - Special Purpose Permit Application; Draft Environmental Assessment; Hawaii-Based Shallow-Set...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-10

    ...-FF01M01000] Special Purpose Permit Application; Draft Environmental Assessment; Hawaii-Based Shallow-Set... the operation of the Hawaii-based shallow-set longline fishery that targets swordfish (Xiphias gladius... albatross, by NMFS in its regulation of the shallow-set longline fishery based in Hawaii. This fishery...

  8. Plant resistance to cold stress: mechanisms and environmental signals triggering frost hardening and dehardening.

    PubMed

    Beck, Erwin H; Heim, Richard; Hansen, Jens

    2004-12-01

    This introductory overview shows that cold, in particular frost, stresses a plant in manifold ways and that the plant's response, being injurious or adaptive, must be considered a syndrome rather than a single reaction. In the course of the year perennial plants of the temperate climate zones undergo frost hardening in autumn and dehardening in spring. Using Scots pine (Pinus sylvestris L.) as a model plant the environmental signals inducing frost hardening and dehardening, respectively, were investigated. Over 2 years the changes in frost resistance of Scots pine needles were recorded together with the annual courses of day-length and ambient temperature. Both act as environmental signals for frost hardening and dehardening. Climate chamber experiments showed that short day-length as a signal triggering frost hardening could be replaced by irradiation with far red light, while red light inhibited hardening. The involvement of phytochrome as a signal receptor could be corroborated by respective night-break experiments. More rapid frost hardening than by short day or far red treatment was achieved by applying a short period (6 h) of mild frost which did not exceed the plant's cold resistance. Both types of signals were independently effective but the rates of frost hardening were not additive. The maximal rate of hardening was - 0.93 degrees C per day and frost tolerance of less than < - 72 degrees C was achieved. For dehardening, temperature was an even more effective signal than day-length.

  9. Firearm trigger assembly

    DOEpatents

    Crandall, David L.; Watson, Richard W.

    2010-02-16

    A firearm trigger assembly for use with a firearm includes a trigger mounted to a forestock of the firearm so that the trigger is movable between a rest position and a triggering position by a forwardly placed support hand of a user. An elongated trigger member operatively associated with the trigger operates a sear assembly of the firearm when the trigger is moved to the triggering position. An action release assembly operatively associated with the firearm trigger assembly and a movable assembly of the firearm prevents the trigger from being moved to the triggering position when the movable assembly is not in the locked position.

  10. Radiation-Triggered Surveillance for UF6 Monitoring

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Curtis, Michael M.

    2015-12-01

    This paper recommends the use of radiation detectors, singly or in sets, to trigger surveillance cameras. Ideally, the cameras will monitor cylinders transiting the process area as well as the process area itself. The general process area will be surveyed to record how many cylinders have been attached and detached to the process between inspections. Rad-triggered cameras can dramatically reduce the quantity of recorded images, because the movement of personnel and equipment not involving UF6 cylinders will not generate a surveillance review file.

  11. Epidemiology of systemic sclerosis: incidence, prevalence, survival, risk factors, malignancy, and environmental triggers.

    PubMed

    Barnes, Jammie; Mayes, Maureen D

    2012-03-01

    To identify the recent data regarding prevalence, incidence, survival, and risk factors for systemic sclerosis (SSc) and to compare these data to previously published findings. SSc disease occurrence data are now available for Argentina, Taiwan, and India and continue to show wide variation across geographic regions. The survival rate is negatively impacted by older age of onset, male sex, scleroderma renal crisis, pulmonary fibrosis, pulmonary arterial hypertension, cancer, and antitopoisomerase and anti-U1 antibodies. It appears that silica exposure confers an increased risk for developing scleroderma, but this exposure accounts for a very small proportion of male patients. Smoking is not associated with increased SSc susceptibility. Malignancies are reported in scleroderma at an increased rate, but the magnitude of this risk and the type of cancer vary among reports. Prevalence and incidence of SSc appears to be greater in populations of European ancestry and lower in Asian groups. Exposure to silica dust appears to be an environmental trigger, but this only accounts for a small proportion of male cases. Evidence for increased risk of neoplasia is suggestive, but the magnitude of the risk and the types of malignancies vary among reports.

  12. Dynamic triggering

    USGS Publications Warehouse

    Hill, David P.; Prejean, Stephanie; Schubert, Gerald

    2015-01-01

    Dynamic stresses propagating as seismic waves from large earthquakes trigger a spectrum of responses at global distances. In addition to locally triggered earthquakes in a variety of tectonic environments, dynamic stresses trigger tectonic (nonvolcanic) tremor in the brittle–plastic transition zone along major plate-boundary faults, activity changes in hydrothermal and volcanic systems, and, in hydrologic domains, changes in spring discharge, water well levels, soil liquefaction, and the eruption of mud volcanoes. Surface waves with periods of 15–200 s are the most effective triggering agents; body-wave trigger is less frequent. Triggering dynamic stresses can be < 1 kPa.

  13. Effect-based trigger values for in vitro bioassays: Reading across from existing water quality guideline values.

    PubMed

    Escher, Beate I; Neale, Peta A; Leusch, Frederic D L

    2015-09-15

    Cell-based bioassays are becoming increasingly popular in water quality assessment. The new generations of reporter-gene assays are very sensitive and effects are often detected in very clean water types such as drinking water and recycled water. For monitoring applications it is therefore imperative to derive trigger values that differentiate between acceptable and unacceptable effect levels. In this proof-of-concept paper, we propose a statistical method to read directly across from chemical guideline values to trigger values without the need to perform in vitro to in vivo extrapolations. The derivation is based on matching effect concentrations with existing chemical guideline values and filtering out appropriate chemicals that are responsive in the given bioassays at concentrations in the range of the guideline values. To account for the mixture effects of many chemicals acting together in a complex water sample, we propose bioanalytical equivalents that integrate the effects of groups of chemicals with the same mode of action that act in a concentration-additive manner. Statistical distribution methods are proposed to derive a specific effect-based trigger bioanalytical equivalent concentration (EBT-BEQ) for each bioassay of environmental interest that targets receptor-mediated toxicity. Even bioassays that are indicative of the same mode of action have slightly different numeric trigger values due to differences in their inherent sensitivity. The algorithm was applied to 18 cell-based bioassays and 11 provisional effect-based trigger bioanalytical equivalents were derived as an illustrative example using the 349 chemical guideline values protective for human health of the Australian Guidelines for Water Recycling. We illustrate the applicability using the example of a diverse set of water samples including recycled water. Most recycled water samples were compliant with the proposed triggers while wastewater effluent would not have been compliant with a few

  14. Diet and lifestyle as trigger factors for the onset of heartburn.

    PubMed

    Oliver, Katie; Davies, Gloria; Dettmar, Peter

    To examine prospectively the role of reported trigger factors on symptom onset in patients with heartburn and highlight the role of these factors in the management of heartburn in the primary care setting. METHOD Twenty-two patients with heartburn and 50 controls were recruited in Bedfordshire, UK. A seven-day symptom and trigger diary was completed by patients and controls. Patients reported a collection of heartburn symptoms varying in severity and time of day. Aspects of diet and lifestyle perceived as trigger factors included large meals, time of eating and posture. Multiple trigger factors were reported for heartburn. Although symptom onset varies between individuals, consideration should be given to trigger factors in the management of heartburn symptoms.

  15. Individual and interpersonal triggers to quit smoking in China: a cross-sectional analysis

    PubMed Central

    Im, Pek Kei; McNeill, Ann; Thompson, Mary E.; Fong, Geoffrey T.; Xu, Steve; Quah, Anne C. K.; Jiang, Yuan; Shahab, Lion

    2015-01-01

    Aims To determine the most prominent individual and interpersonal triggers to quit smoking in China and their associations with socio-demographic characteristics. Methods Data come from Waves 1-3 (2006-2009) of the ITC China Survey, analysed cross-sectionally as person-waves (N=14,358). Measures included socio-demographic and smoking characteristics. Those who quit between waves (4.3%) were asked about triggers that “very much” led them to stop smoking, and continuing smokers about triggers that “very much” made them think about quitting. Triggers covered individual (personal health concerns, cigarette price, smoking restrictions, advertisements, warning labels) and interpersonal factors (family/societal disapproval of smoking, setting an example to children, concerns about second-hand smoke). Results Over a third of respondents (34.9%) endorsed at least one trigger strongly; quitters were more likely than smokers to mention any trigger. While similar proportions of smokers endorsed individual (24.4%) and interpersonal triggers (24.0%), quitters endorsed more individual (61.1%) than interpersonal (48.3%) triggers. However, the most common triggers (‘personal health concerns’; ‘setting an example to children’) were the same, endorsed by two-thirds of quitters and a quarter of smokers, as were the least common triggers (‘warning labels’; ‘cigarette price’), endorsed by one in ten quitters and one in twenty smokers. Lower dependence among smokers and greater education among all respondents were associated with endorsing any trigger. Conclusions Individual rather than interpersonal triggers appear more important for quitters. Major opportunities to motivate quit attempts are missed in China, particularly with regard to taxation and risk communication. Interventions need to focus on more dependent and less-educated smokers. PMID:25888422

  16. SU-E-J-141: Assessment of the Magnitude and Impact of Trigger Delay in Respiratory Triggered Real-Time Imaging during Radiotherapy.

    PubMed

    Duan, J; Shen, S; Popple, R; Wu, X; Cardan, R; Brezovich, I

    2012-06-01

    To assess the trigger delay in respiratory triggered real-time imaging and its impact on image guided radiotherapy (IGRT) with Varian TrueBeam System. A sinusoidal motion phantom with 2cm motion amplitude was used. The trigger delay was determined directly with video image, and indirectly by the distance between expected and actual triggering phantom positions. For the direct method, a fluorescent screen was placed on the phantom to visualize the x-ray. The motion of the screen was recorded at 60 frames/second. The number of frames between the time when the phantom reached expected triggering position and the time when the screen was illuminated by the x-ray was used to determine the trigger delay. In the indirect method, triggered kV x-ray images were acquired in real-time during 'treatment' with triggers set at 25% and 75% respiratory phases where the phantom moved at the maximum speed. 39-40 triggered images were acquired continuously in each series. The distance between the expected and actual triggering points, d, was measured on the images to determine the delay time t by d=Asin(wt), where w=2π/T, T=period and A=amplitude. Motion periods of 2s and 4s were used in the measurement. The trigger delay time determined with direct video imaging was 125ms (7.5 video frames). The average distance between the expected and actual triggering positions determined by the indirect method was 3.93±0.74mm for T=4s and 7.02±1.25mm for T=2s, yielding mean trigger delay times of 126±24ms and 120±22ms, respectively. Although the mean over-travel distance is significant at 25% and 75% phases, clinically, the target over-travel resulted from the trigger delay at the end of expiration (50% phase) is negligibly small(< 0.5mm). The trigger delay in respiration-triggered imaging is in the range of 120-126ms. This delay has negligible clinical effect on gated IGRT. © 2012 American Association of Physicists in Medicine.

  17. Environmental Trigger(s) of Type 1 Diabetes: Why So Difficult to Identify?

    PubMed Central

    2015-01-01

    Type 1 diabetes (T1D) is one of the most common chronic diseases with childhood onset, and the disease has increased two- to fivefold over the past half century by as yet unknown means. T1D occurs when the body's immune system turns against itself so that, in a very specific and targeted way, it destroys the pancreatic β-cells. T1D results from poorly defined interactions between susceptibility genes and environmental determinants. In contrast to the rapid progress in finding T1D genes, identification and confirmation of environmental determinants remain a formidable challenge. This review article will focus on factors which have to be evaluated and decision to take before starting a new prospective cohort study. Considering all the large ongoing prospective studies, new and more conclusive data than that obtained so far should instead come from international collaboration on the ongoing cohort studies. PMID:25883954

  18. A Parameterization for the Triggering of Landscape Generated Moist Convection

    NASA Technical Reports Server (NTRS)

    Lynn, Barry H.; Tao, Wei-Kuo; Abramopoulos, Frank

    1998-01-01

    A set of relatively high resolution three-dimensional (3D) simulations were produced to investigate the triggering of moist convection by landscape generated mesoscale circulations. The local accumulated rainfall varied monotonically (linearly) with the size of individual landscape patches, demonstrating the need to develop a trigger function that is sensitive to the size of individual patches. A new triggering function that includes the effect of landscapes generated mesoscale circulations over patches of different sizes consists of a parcel's perturbation in vertical velocity (nu(sub 0)), temperature (theta(sub 0)), and moisture (q(sub 0)). Each variable in the triggering function was also sensitive to soil moisture gradients, atmospheric initial conditions, and moist processes. The parcel's vertical velocity, temperature, and moisture perturbation were partitioned into mesoscale and turbulent components. Budget equations were derived for theta(sub 0) and q(sub 0). Of the many terms in this set of budget equations, the turbulent, vertical flux of the mesoscale temperature and moisture contributed most to the triggering of moist convection through the impact of these fluxes on the parcel's temperature and moisture profile. These fluxes needed to be parameterized to obtain theta(sub 0) and q(sub 0). The mesoscale vertical velocity also affected the profile of nu(sub 0). We used similarity theory to parameterize these fluxes as well as the parcel's mesoscale vertical velocity.

  19. Control of asthma triggers in indoor air with air cleaners: a modeling analysis.

    PubMed

    Myatt, Theodore A; Minegishi, Taeko; Allen, Joseph G; Macintosh, David L

    2008-08-06

    Reducing exposure to environmental agents indoors shown to increase asthma symptoms or lead to asthma exacerbations is an important component of a strategy to manage asthma for individuals. Numerous investigations have demonstrated that portable air cleaning devices can reduce concentrations of asthma triggers in indoor air; however, their benefits for breathing problems have not always been reproducible. The potential exposure benefits of whole house high efficiency in-duct air cleaners for sensitive subpopulations have yet to be evaluated. We used an indoor air quality modeling system (CONTAM) developed by NIST to examine peak and time-integrated concentrations of common asthma triggers present in indoor air over a year as a function of natural ventilation, portable air cleaners, and forced air ventilation equipped with conventional and high efficiency filtration systems. Emission rates for asthma triggers were based on experimental studies published in the scientific literature. Forced air systems with high efficiency filtration were found to provide the best control of asthma triggers: 30-55% lower cat allergen levels, 90-99% lower risk of respiratory infection through the inhalation route of exposure, 90-98% lower environmental tobacco smoke (ETS) levels, and 50-75% lower fungal spore levels than the other ventilation/filtration systems considered. These results indicate that the use of high efficiency in-duct air cleaners provide an effective means of controlling allergen levels not only in a single room, like a portable air cleaner, but the whole house. These findings are useful for evaluating potential benefits of high efficiency in-duct filtration systems for controlling exposure to asthma triggers indoors and for the design of trials of environmental interventions intended to evaluate their utility in practice.

  20. ER stress triggers MCP-1 expression through SET7/9-induced histone methylation in the kidneys of db/db mice.

    PubMed

    Chen, Jigang; Guo, Yanhong; Zeng, Wei; Huang, Li; Pang, Qi; Nie, Ling; Mu, Jiao; Yuan, Fahuan; Feng, Bing

    2014-04-15

    Epigenetics plays a key role in the pathogenesis of diabetic nephropathy (DN), although the precise regulatory mechanism is still unclear. Here, we examined the role of endoplasmic reticulum (ER) stress in histone H3 lysine 4 (H3K4) methyltransferase SET7/9-induced monocyte chemoattractant protein-1 (MCP-1) expression in the kidneys of db/db mice. Our results indicate that the expression of MCP-1 significantly increased in the kidneys of db/db mice in a time-dependent manner. An increased chromatin mark associated with an active gene (H3K4me1) at MCP-1 promoters accompanied this change in expression. The expression of SET7/9 and the recruitment to these promoters were also elevated. SET7/9 gene silencing with small interfering (si) RNAs significantly attenuated the expression of H3K4me1 and MCP-1. Furthermore, expression of signaling regulator glucose-regulated protein 78 (GRP78), a monitor of ER stress, significantly increased in the kidneys of db/db mice. The expression of spliced X-box binding protein 1 (XBP1s), an ER stress-inducible transcription factor, and recruitment to the SET7/9 promoters were also increased. XBP1s gene silencing with siRNAs significantly attenuated the expression of SET7/9, H3K4me1, and MCP-1. The chaperone betaine not only effectively downregulated the GRP78 and XBP1s expression levels but also markedly decreased the SET7/9, H3K4me1, and MCP-1 levels. Luciferase reporter assay demonstrated that XBP1s participated in ER stress-induced SET7/9 transcription, Taken together, these results reveal that ER stress can trigger the expression of MCP-1, in part through the XBP1s-mediated induction of SET7/9.

  1. Note: Novel trigger pulse feed method for mega-volt gas switch.

    PubMed

    Yin, Jiahui; Sun, Fengju; Jiang, Xiaofeng; Wang, Zhiguo; Liang, Tianxue; Jiang, Hongyu; Qiu, Aici

    2017-07-01

    It is difficult to feed the trigger pulse into an electrically triggered mega-volt switch, and the present note presents a novel trigger pulse feed method. The trigger pulse is introduced via a damping resistor, which is mounted between the inner and outer cylindrical electrodes of the pulse transmission line. The mega-volt pulse is damped because the voltage is resistively divided by the resistor and trigger cable arrangement. Both the complex breakdown processes of the switch and its insulation issues are experimentally studied. The function and the beneficial effects of the damping resistor, installed together with an additional inductor, are discussed. Finally, the parameters of these two damping components are set to 500 Ω and 2 μH values for which the switch has been demonstrated to work successfully at over 2.3 MV.

  2. Considerations for estimating microbial environmental data concentrations collected from a field setting

    PubMed Central

    Silvestri, Erin E; Yund, Cynthia; Taft, Sarah; Bowling, Charlena Yoder; Chappie, Daniel; Garrahan, Kevin; Brady-Roberts, Eletha; Stone, Harry; Nichols, Tonya L

    2017-01-01

    In the event of an indoor release of an environmentally persistent microbial pathogen such as Bacillus anthracis, the potential for human exposure will be considered when remedial decisions are made. Microbial site characterization and clearance sampling data collected in the field might be used to estimate exposure. However, there are many challenges associated with estimating environmental concentrations of B. anthracis or other spore-forming organisms after such an event before being able to estimate exposure. These challenges include: (1) collecting environmental field samples that are adequate for the intended purpose, (2) conducting laboratory analyses and selecting the reporting format needed for the laboratory data, and (3) analyzing and interpreting the data using appropriate statistical techniques. This paper summarizes some key challenges faced in collecting, analyzing, and interpreting microbial field data from a contaminated site. Although the paper was written with considerations for B. anthracis contamination, it may also be applicable to other bacterial agents. It explores the implications and limitations of using field data for determining environmental concentrations both before and after decontamination. Several findings were of interest. First, to date, the only validated surface/sampling device combinations are swabs and sponge-sticks on stainless steel surfaces, thus limiting availability of quantitative analytical results which could be used for statistical analysis. Second, agreement needs to be reached with the analytical laboratory on the definition of the countable range and on reporting of data below the limit of quantitation. Finally, the distribution of the microbial field data and statistical methods needed for a particular data set could vary depending on these data that were collected, and guidance is needed on appropriate statistical software for handling microbial data. Further, research is needed to develop better methods to

  3. Identifying Potential Ventilator Auto-Triggering Among Organ Procurement Organization Referrals.

    PubMed

    Henry, Nicholas R; Russian, Christopher J; Nespral, Joseph

    2016-06-01

    Ventilator auto-trigger is the delivery of an assisted mechanical ventilated breath over the set ventilator frequency in the absence of a spontaneous inspiratory effort and can be caused by inappropriate ventilator trigger sensitivity. Ventilator auto-trigger can be misinterpreted as a spontaneous breath and has the potential to delay or prevent brain death testing and confuse health-care professionals and/or patient families. To determine the frequency of organ donor referrals from 1 Organ Procurement Organization (OPO) that could benefit from an algorithm designed to assist organ recovery coordinators to identify and correct ventilator auto-triggering. This retrospective analysis evaluated documentation of organ donor referrals from 1 OPO in central Texas during the 2013 calendar year that resulted in the withdrawal of care by the patient's family and the recovery of organs. The frequency of referrals that presented with absent brain stem reflexes except for additional respirations over the set ventilator rate was determined to assess for the need of the proposed algorithm. Documentation of 672 organ procurement organization referrals was evaluated. Documentation from 42 referrals that resulted in the withdrawal of care and 21 referrals that resulted in the recovery of organs were identified with absent brain stem reflexes except for spontaneous respirations on the mechanical ventilator. As a result, an algorithm designed to identify and correct ventilator auto-trigger could have been used 63 times during the 2013 calendar year. © 2016, NATCO.

  4. Control of asthma triggers in indoor air with air cleaners: a modeling analysis

    PubMed Central

    Myatt, Theodore A; Minegishi, Taeko; Allen, Joseph G; MacIntosh, David L

    2008-01-01

    Background Reducing exposure to environmental agents indoors shown to increase asthma symptoms or lead to asthma exacerbations is an important component of a strategy to manage asthma for individuals. Numerous investigations have demonstrated that portable air cleaning devices can reduce concentrations of asthma triggers in indoor air; however, their benefits for breathing problems have not always been reproducible. The potential exposure benefits of whole house high efficiency in-duct air cleaners for sensitive subpopulations have yet to be evaluated. Methods We used an indoor air quality modeling system (CONTAM) developed by NIST to examine peak and time-integrated concentrations of common asthma triggers present in indoor air over a year as a function of natural ventilation, portable air cleaners, and forced air ventilation equipped with conventional and high efficiency filtration systems. Emission rates for asthma triggers were based on experimental studies published in the scientific literature. Results Forced air systems with high efficiency filtration were found to provide the best control of asthma triggers: 30–55% lower cat allergen levels, 90–99% lower risk of respiratory infection through the inhalation route of exposure, 90–98% lower environmental tobacco smoke (ETS) levels, and 50–75% lower fungal spore levels than the other ventilation/filtration systems considered. These results indicate that the use of high efficiency in-duct air cleaners provide an effective means of controlling allergen levels not only in a single room, like a portable air cleaner, but the whole house. Conclusion These findings are useful for evaluating potential benefits of high efficiency in-duct filtration systems for controlling exposure to asthma triggers indoors and for the design of trials of environmental interventions intended to evaluate their utility in practice. PMID:18684328

  5. Full-scale physical model of landslide triggering

    NASA Astrophysics Data System (ADS)

    Lora, M.; Camporese, M.; Salandin, P.

    2013-12-01

    Landslide triggering induced by high-intensity rainfall infiltration in hillslopes is a complex phenomenon that involves hydrological processes operating at different spatio-temporal scales. Empirical methods give rough information about landslide-prone areas, without investigating the theoretical framework needed to achieve an in-depth understanding of the involved physical processes. In this study, we tackle this issue through physical experiments developed in an artificial hillslope realized in the Department of Civil, Environmental and Architectural Engineering of the University of Padua. The structure consists of a reinforced concrete box containing a soil prism with the following maximum dimensions: 3.5 m high, 6 m long, and 2 m wide. In order to analyze and examine the triggered failure state, the experiments are carried out with intensive monitoring of pore water pressure and moisture content response. Subsurface monitoring instruments are installed at several locations and depths to measure downward infiltration and/or a rising groundwater table. We measure the unsaturated soil water pressure as well as positive pore pressures preceding failure in each experiments with six tensiometers. The volumetric water content is determined through six Time Domain Reflectometry probes. Two pressure transducers are located in observation wells to determine the position of the water table in time. Two stream gauges are positioned at the toeslope, for measuring both runoff and subsurface outflow. All data are collected and recorded by an acquisition data system from Campbell Scientific. The artificial hillslope is characterized by well-known and controlled conditions, which are designed to reproduce an ideal set-up susceptible to heavy rainfall landslide. The hydrologic forcing is generated by a rainfall simulator realized with nozzles from Sprying System and. specifically designed to produce a spatially uniform rainfall of intensity ranging from 50 to 150 mm/h. The aim

  6. Optical techniques for biological triggers and identifiers

    NASA Astrophysics Data System (ADS)

    Grant, Bruce A. C.

    2004-12-01

    Optical techniques for the classification and identification of biological particles provide a number of advantages over traditional 'Wet Chemistry" methods, amongst which are speed of response and the reduction/elimination of consumables. These techniques can be employed in both 'Trigger" and 'Identifier" systems. Trigger systems monitor environmental particulates with the aim of detecting 'unusual" changes in the overall environmental composition and providing an indication of threat. At the present time there is no single optical measurement that can distinguish between benign and hostile events. Therefore, in order to distinguish between these 2 classifications, a number of different measurements must be effected and a decision made on the basis of the 'integrated" data. Smiths Detection have developed a data gathering platform capable of measuring multiple optical, physical and electrical parameters of individual airborne biological particles. The data from all these measurements are combined in a hazard classification algorithm based on Bayesian Inference techniques. Identifier systems give a greater level of information and confidence than triggers, -- although they require reagents and are therefore much more expensive to operate -- and typically take upwards of 20 minutes to respond. Ideally, in a continuous flow mode, identifier systems would respond in real-time, and identify a range of pathogens specifically and simultaneously. The results of recent development work -- carried out by Smiths Detection and its collaborators -- to develop an optical device that meets most of these requirements, and has the stretch potential to meet all of the requirements in a 3-5 year time frame will be presented. This technology enables continuous stand-alone operation for both civil and military defense applications and significant miniaturisation can be achieved with further development.

  7. Remotely triggered nonvolcanic tremor in Sumbawa, Indonesia

    NASA Astrophysics Data System (ADS)

    Fuchs, Florian; Lupi, Matteo; Miller, Stephen

    2015-04-01

    Nonvolcanic (or tectonic) tremor is a seismic phenomenom which can provide important information about dynamics of plate boundaries but the underlying mechanisms are not well understood. Tectonic tremor is often associated with slow-slip (termed episodic tremor and slip) and understanding the mechanisms driving tremor presents an important challenge because it is likely a dominant aspect of the evolutionary processes leading to tsunamigenic, megathrust subduction zone earthquakes. Tectonic tremor is observed worldwide, mainly along major subduction zones and plate boundaries such as in Alaska/Aleutians, Cascadia, the San Andreas Fault, Japan or Taiwan. We present, for the first time, evidence for triggered tremor beneath the island of Sumbawa, Indonesia. The island of Sumbawa, Indonesia, is part of the Lesser Sunda Group about 250 km north of the Australian/Eurasian plate collision at the Java Trench with a convergence rate of approximately 70 mm/yr. We show surface wave triggered tremor beneath Sumbawa in response to three teleseismic earthquakes: the Mw9.0 2011 Tohoku earthquake and two oceanic strike-slip earthquakes (Mw 8.6 and Mw8.2) offshore of Sumatra in 2012. Tremor amplitudes scale with ground motion and peak at 180 nm/s ground velocity on the horizontal components. A comparison of ground motion of the three triggering events and a similar (nontriggering) Mw7.6 2012 Philippines event constrains an apparent triggering threshold of approximately 1 mm/s ground velocity or 8 kPa dynamic stress. Surface wave periods of 45-65 s appear optimal for triggering tremor at Sumbawa which predominantly correlates with Rayleigh waves, even though the 2012 oceanic events have stronger Love wave amplitudes and triggering potential. Rayleigh wave triggering, low-triggering amplitudes, and the tectonic setting all favor a model of tremor generated by localized fluid transport. We could not locate the tremor because of minimal station coverage, but data indicate several

  8. The Delivery of Health Promotion and Environmental Health Services; Public Health or Primary Care Settings?

    PubMed

    Bjørn Jensen, Lene; Lukic, Irena; Gulis, Gabriel

    2018-05-07

    The WHO Regional Office for Europe developed a set of public health functions resulting in the ten Essential Public Health Operations (EPHO). Public health or primary care settings seem to be favorable to embrace all actions included into EPHOs. The presented paper aims to guide readers on how to assign individual health promotion and environmental health services to public health or primary care settings. Survey tools were developed based on EPHO 2, 3 and 4; there were six key informant surveys out of 18 contacted completed via e-mails by informants working in Denmark on health promotion and five face-to-face interviews were conducted in Australia (Melbourne and Victoria state) with experts from environmental health, public health and a physician. Based on interviews, we developed a set of indicators to support the assignment process. Population or individual focus, a system approach or one-to-one approach, dealing with hazards or dealing with effects, being proactive or reactive were identified as main element of the decision tool. Assignment of public health services to one of two settings proved to be possible in some cases, whereas in many there is no clear distinction between the two settings. National context might be the one which guides delivery of public health services.

  9. Early anther ablation triggers parthenocarpic fruit development in tomato.

    PubMed

    Medina, Mónica; Roque, Edelín; Pineda, Benito; Cañas, Luis; Rodriguez-Concepción, Manuel; Beltrán, José Pío; Gómez-Mena, Concepción

    2013-08-01

    Fruit set and fruit development in tomato is largely affected by changes in environmental conditions, therefore autonomous fruit set independent of fertilization is a highly desirable trait in tomato. Here, we report the production and characterization of male-sterile transgenic plants that produce parthenocarpic fruits in two tomato cultivars (Micro-Tom and Moneymaker). We generated male-sterility using the cytotoxic gene barnase targeted to the anthers with the PsEND1 anther-specific promoter. The ovaries of these plants grew in the absence of fertilization producing seedless, parthenocarpic fruits. Early anther ablation is essential to trigger the developing of the transgenic ovaries into fruits, in the absence of the signals usually generated during pollination and fertilization. Ovaries are fully functional and can be manually pollinated to obtain seeds. The transgenic plants obtained in the commercial cultivar Moneymaker show that the parthenocarpic development of the fruit does not have negative consequences in fruit quality. Throughout metabolomic analyses of the tomato fruits, we have identified two elite lines which showed increased levels of several health promoting metabolites and volatile compounds. Thus, early anther ablation can be considered a useful tool to promote fruit set and to obtain seedless and good quality fruits in tomato plants. These plants are also useful parental lines to be used in hybrid breeding approaches. © 2013 Society for Experimental Biology, Association of Applied Biologists and John Wiley & Sons Ltd.

  10. Where do we stand after twenty years of dynamic triggering studies? (Invited)

    NASA Astrophysics Data System (ADS)

    Prejean, S. G.; Hill, D. P.

    2013-12-01

    In the past two decades, remote dynamic triggering of earthquakes by other earthquakes has been explored in a variety of physical environments with a wide array of observation and modeling techniques. These studies have significantly refined our understanding of the state of the crust and the physical conditions controlling earthquake nucleation. Despite an ever growing database of dynamic triggering observations, significant uncertainties remain and vigorous debate in almost all aspects of the science continues. For example, although dynamic earthquake triggering can occur with peak dynamic stresses as small as 1 kPa, triggering thresholds and their dependence on local stress state, hydrological environment, and frictional properties of faults are not well understood. Some studies find a simple threshold based on the peak amplitude of shaking while others find dependencies on frequency, recharge time, and other parameters. Considerable debate remains over the range of physical processes responsible for dynamic triggering, and the wide variation in dynamic triggering responses and time scales suggests triggering by multiple physical processes. Although Coulomb shear failure with various friction laws can often explain dynamic triggering, particularly instantaneous triggering, delayed dynamic triggering may be dependent on fluid transport and other slowly evolving aseismic processes. Although our understanding of the global distribution of dynamic triggering has improved, it is far from complete due to spatially uneven monitoring. A major challenge involves establishing statistical significance of potentially triggered earthquakes, particularly if they are isolated events or time-delayed with respect to triggering stresses. Here we highlight these challenges and opportunities with existing data. We focus on environmental dependence of dynamic triggering by large remote earthquakes particularly in volcanic and geothermal systems, as these systems often have high

  11. 40 CFR 227.3 - Materials which do not satisfy the environmental impact criteria set forth in subpart B.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... environmental impact criteria set forth in subpart B. 227.3 Section 227.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING CRITERIA FOR THE EVALUATION OF PERMIT APPLICATIONS FOR OCEAN DUMPING OF MATERIALS General § 227.3 Materials which do not satisfy the environmental impact...

  12. 40 CFR 227.3 - Materials which do not satisfy the environmental impact criteria set forth in subpart B.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... environmental impact criteria set forth in subpart B. 227.3 Section 227.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING CRITERIA FOR THE EVALUATION OF PERMIT APPLICATIONS FOR OCEAN DUMPING OF MATERIALS General § 227.3 Materials which do not satisfy the environmental impact...

  13. 40 CFR 227.3 - Materials which do not satisfy the environmental impact criteria set forth in subpart B.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... environmental impact criteria set forth in subpart B. 227.3 Section 227.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING CRITERIA FOR THE EVALUATION OF PERMIT APPLICATIONS FOR OCEAN DUMPING OF MATERIALS General § 227.3 Materials which do not satisfy the environmental impact...

  14. 40 CFR 227.3 - Materials which do not satisfy the environmental impact criteria set forth in subpart B.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... environmental impact criteria set forth in subpart B. 227.3 Section 227.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING CRITERIA FOR THE EVALUATION OF PERMIT APPLICATIONS FOR OCEAN DUMPING OF MATERIALS General § 227.3 Materials which do not satisfy the environmental impact...

  15. 40 CFR 227.3 - Materials which do not satisfy the environmental impact criteria set forth in subpart B.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... environmental impact criteria set forth in subpart B. 227.3 Section 227.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING CRITERIA FOR THE EVALUATION OF PERMIT APPLICATIONS FOR OCEAN DUMPING OF MATERIALS General § 227.3 Materials which do not satisfy the environmental impact...

  16. Plant cell wall-mediated immunity: cell wall changes trigger disease resistance responses.

    PubMed

    Bacete, Laura; Mélida, Hugo; Miedes, Eva; Molina, Antonio

    2018-02-01

    Plants have evolved a repertoire of monitoring systems to sense plant morphogenesis and to face environmental changes and threats caused by different attackers. These systems integrate different signals into overreaching triggering pathways which coordinate developmental and defence-associated responses. The plant cell wall, a dynamic and complex structure surrounding every plant cell, has emerged recently as an essential component of plant monitoring systems, thus expanding its function as a passive defensive barrier. Plants have a dedicated mechanism for maintaining cell wall integrity (CWI) which comprises a diverse set of plasma membrane-resident sensors and pattern recognition receptors (PRRs). The PRRs perceive plant-derived ligands, such as peptides or wall glycans, known as damage-associated molecular patterns (DAMPs). These DAMPs function as 'danger' alert signals activating DAMP-triggered immunity (DTI), which shares signalling components and responses with the immune pathways triggered by non-self microbe-associated molecular patterns that mediate disease resistance. Alteration of CWI by impairment of the expression or activity of proteins involved in cell wall biosynthesis and/or remodelling, as occurs in some plant cell wall mutants, or by wall damage due to colonization by pathogens/pests, activates specific defensive and growth responses. Our current understanding of how these alterations of CWI are perceived by the wall monitoring systems is scarce and few plant sensors/PRRs and DAMPs have been characterized. The identification of these CWI sensors and PRR-DAMP pairs will help us to understand the immune functions of the wall monitoring system, and might allow the breeding of crop varieties and the design of agricultural strategies that would enhance crop disease resistance. © 2017 The Authors The Plant Journal © 2017 John Wiley & Sons Ltd.

  17. Holocene earthquake-triggered turbidites from the Saguenay (Eastern Canada) and Reloncavi (Chilean margin) fjords

    NASA Astrophysics Data System (ADS)

    St-Onge, Guillaume; Chapron, Emmanuel; Mulsow, Sandor; Salas, Marcos; Debret, Maxime; Foucher, Anthony; Mulder, Thierry; Desmet, Marc; Costa, Pedro; Ghaleb, Bassam; Locat, Jacques

    2013-04-01

    Fjords are unique archives of climatic and environmental changes, but also of natural hazards. They can preserve thick sedimentary sequences deposited under very high sediment accumulation rates, making them ideally suited to record historical and pre-historical sedimentological events such as major landslides, floods or earthquakes. In fact, by carefully characterizing and dating the sediments and by comparing the basin fill seismic stratigraphy and sedimentary records with historical events, it is possible to "calibrate" recent rapidly deposited layers such as turbidites with a trigger mechanism and extend these observations further back in time by using seismic reflection profiles and longer sediment cores. Here, we will compare earthquake-triggered turbidites in fjords from the Southern and Northern Hemispheres: the Saguenay (Eastern Canada) and Reloncavi fjords (southern Chilean margin). In both settings, we will first look at basin fill geometries and at the sedimentological properties of historical events before extending the records further back in time. In both fjords, several turbidites were associated with large magnitude historic and pre-historic earthquakes including the 1663 AD (M>7) earthquake in the Saguenay Fjord, and the 1960 (M 9.5), 1837 (M~8) and 1575 AD major Chilean subduction earthquakes in the Reloncavi Fjord. In addition, a sand layer with sea urchin fragments and the exoscopic characteristics typical of a tsunami deposit was observed immediately above the turbidite associated with the 1575 AD earthquake in the Reloncavi Fjord and supports both the chronology and the large magnitude of that historic earthquake. In both fjords, as well as in other recently recognized earthquake-triggered turbidites, the decimeter-to meter-thick normally-graded turbidites are characterized by a homogeneous, but slightly fining upward tail. Finally, new radiocarbon results will be presented and indicate that at least 19 earthquake-triggered turbidites were

  18. Walden Pond, Massachusetts: Environmental Setting and Current Investigations

    USGS Publications Warehouse

    Colman, John A.; Waldron, Marcus C.

    1998-01-01

    Introduction Walden Pond, in Concord, Massachusetts, is famous among lakes because of its unique social history. Walden was the setting for American naturalist Henry David Thoreau's well-known essay 'Walden; or, Life in the Woods,' first published in 1854. Thoreau lived and wrote at Walden Pond from July 1845 to September 1847. In 'Walden,' Thoreau combined highly admired writing on Transcendental philosophy with pioneering observations of aquatic ecology and physical aspects of limnology, the study of lakes. Because Thoreau also defended so effectively the value of living close to nature in the Walden woods, the pond is considered by many to be the birthplace of the American conservation movement. Visitors come from all over the world to the pond, which has been designated a National Historic Landmark, and its fame has resulted in a major fund drive to preserve the surrounding woods. Walden Pond has no surfacewater inflow or outflow, and much of its ground-water contributing area likely is preserved within the Walden Pond Reservation area (fig. 1). Only 15 miles from Boston, the pond is unusually clear and pristine for an urban-area lake. However, point sources of nutrients near the pond, and a large annual visitor attendance, concentrated during the summer when the swimming beach (fig. 2) is open, may contribute a nutrient load sufficient to change the pond environment. The occurrence of nuisance algal species, a recent beach closing, and an awareness of water-quality problems suffered by other ponds in the region raise concerns about the risk of ecological change at Walden Pond. Despite the role of Walden Pond as a cultural and environmental icon, little is known about the pond's ecological features, such as its internal nutrient cycling or the structure of its food web, nor have consistent measurements been made to determine whether these features are changing or are stable. Production rates of aquatic plants in lakes and ponds naturally undergo a slow increase

  19. Freddie Fish. A Primary Environmental Study of Basic Numerals, Sets, Ordinals and Shapes.

    ERIC Educational Resources Information Center

    Kraynak, Ola

    This teacher's guide and study guide are an environmental approach to mathematics education in the primary grades. The mathematical studies of the numerals 0-10, ordinals, number sets, and basic shapes - diamond, circle, square, rectangle, and triangle - are developed through the story of Freddie Fish and his search for clean water. The…

  20. Lessons from (triggered) tremor

    USGS Publications Warehouse

    Gomberg, Joan

    2010-01-01

    I test a “clock-advance” model that implies triggered tremor is ambient tremor that occurs at a sped-up rate as a result of loading from passing seismic waves. This proposed model predicts that triggering probability is proportional to the product of the ambient tremor rate and a function describing the efficacy of the triggering wave to initiate a tremor event. Using data mostly from Cascadia, I have compared qualitatively a suite of teleseismic waves that did and did not trigger tremor with ambient tremor rates. Many of the observations are consistent with the model if the efficacy of the triggering wave depends on wave amplitude. One triggered tremor observation clearly violates the clock-advance model. The model prediction that larger triggering waves result in larger triggered tremor signals also appears inconsistent with the measurements. I conclude that the tremor source process is a more complex system than that described by the clock-advance model predictions tested. Results of this and previous studies also demonstrate that (1) conditions suitable for tremor generation exist in many tectonic environments, but, within each, only occur at particular spots whose locations change with time; (2) any fluid flow must be restricted to less than a meter; (3) the degree to which delayed failure and secondary triggering occurs is likely insignificant; and 4) both shear and dilatational deformations may trigger tremor. Triggered and ambient tremor rates correlate more strongly with stress than stressing rate, suggesting tremor sources result from time-dependent weakening processes rather than simple Coulomb failure.

  1. An FPGA-based trigger for the phase II of the MEG experiment

    NASA Astrophysics Data System (ADS)

    Baldini, A.; Bemporad, C.; Cei, F.; Galli, L.; Grassi, M.; Morsani, F.; Nicolò, D.; Ritt, S.; Venturini, M.

    2016-07-01

    For the phase II of MEG, we are going to develop a combined trigger and DAQ system. Here we focus on the former side, which operates an on-line reconstruction of detector signals and event selection within 450 μs from event occurrence. Trigger concentrator boards (TCB) are under development to gather data from different crates, each connected to a set of detector channels, to accomplish higher-level algorithms to issue a trigger in the case of a candidate signal event. We describe the major features of the new system, in comparison with phase I, as well as its performances in terms of selection efficiency and background rejection.

  2. Dysregulation of autism-associated synaptic proteins by psychoactive pharmaceuticals at environmental concentrations.

    PubMed

    Kaushik, Gaurav; Xia, Yu; Pfau, Jean C; Thomas, Michael A

    2017-11-20

    Autism Spectrum Disorders (ASD) are complex neurological disorders for which the prevalence in the U.S. is currently estimated to be 1 in 50 children. A majority of cases of idiopathic autism in children likely result from unknown environmental triggers in genetically susceptible individuals. These triggers may include maternal exposure of a developing embryo to environmentally relevant minute concentrations of psychoactive pharmaceuticals through ineffectively purified drinking water. Previous studies in our lab examined the extent to which gene sets associated with neuronal development were up- and down-regulated (enriched) in the brains of fathead minnows treated with psychoactive pharmaceuticals at environmental concentrations. The aim of this study was to determine whether similar treatments would alter in vitro expression of ASD-associated synaptic proteins on differentiated human neuronal cells. Human SK-N-SH neuroblastoma cells were differentiated for two weeks with 10μM retinoic acid (RA) and treated with environmentally relevant concentrations of fluoxetine, carbamazepine or venlafaxine, and flow cytometry technique was used to analyze expression of ASD-associated synaptic proteins. Data showed that carbamazepine individually, venlafaxine individually and mixture treatment at environmental concentrations significantly altered the expression of key synaptic proteins (NMDAR1, PSD95, SV2A, HTR1B, HTR2C and OXTR). Data indicated that psychoactive pharmaceuticals at extremely low concentrations altered the in vitro expression of key synaptic proteins that may potentially contribute to neurological disorders like ASD by disrupting neuronal development. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Effect of environmental setting on sediment, nitrogen, and phosphorus concentrations in Albemarle-Pamlico drainage basin, North Carolina and Virginia, USA

    USGS Publications Warehouse

    McMahon, G.; Harned, D.A.

    1998-01-01

    Environmental settings were defined, through an overlay process, as areas of coincidence between categories of three mapped variables - land use, surficial geology, and soil drainage characteristics. Expert judgment was used in selecting factors thought to influence sediment and nutrient concentrations in the Albemarle-Pamlico drainage area. This study's findings support the hypothesis that environmental settings defined using these three variables can explain variations in the concentration of certain sediment and nutrient constituents. This finding underscores the importance of developing watershed management plans that account for differences associated with the mosaic of natural and anthropogenic factors that define a basin's environmental setting. At least in the case of sediment and nutrients in the Albemarle-Pamlico region, a watershed management plan that focuses only on anthropogenic factors, such as point-source discharges, and does not account for natural characteristics of a watershed and the influences of these characteristics on water quality, may lead to water-quality goals that are over- or underprotective of key environmental features and to a misallocation of the resources available for environmental protection.

  4. On the sensitivity of transtensional versus transpressional tectonic regimes to remote dynamic triggering by Coulomb failure

    USGS Publications Warehouse

    Hill, David P.

    2015-01-01

     Accumulating evidence, although still strongly spatially aliased, indicates that although remote dynamic triggering of small-to-moderate (Mw<5) earthquakes can occur in all tectonic settings, transtensional stress regimes with normal and subsidiary strike-slip faulting seem to be more susceptible to dynamic triggering than transpressional regimes with reverse and subsidiary strike-slip faulting. Analysis of the triggering potential of Love- and Rayleigh-wave dynamic stresses incident on normal, reverse, and strike-slip faults assuming Andersonian faulting theory and simple Coulomb failure supports this apparent difference for rapid-onset triggering susceptibility.

  5. Trigger Finger (Stenosing Tenosynovitis)

    MedlinePlus

    ... Trigger Finger Find a hand surgeon near you. Videos Trigger Finger Animation Trigger Finger Close Popup Close ... or "in." Also, avoid using media types like "video," "article," and "picture." Tip 4: Your results can ...

  6. Managing environmental sustainability in a healthcare setting.

    PubMed

    Langstaff, Karen; Brzozowski, Victoria

    2017-03-01

    How does a hospital sustain its journey towards environmental sustainability? To date, most hospitals have embarked on some strategies for improving environmental performance, whether it's reducing energy or landfill waste. Environmental sustainability strategies, however, can often lose momentum or stagnate if not championed by someone whose full-time role is to assess, monitor, and bring new strategies to the table. In the face of ongoing budget deficits, it is increasingly difficult to get adequate support and buy-in for this type of role unless the leadership of the organization is committed to an environmental sustainability program. This article will examine the strategies and outcomes of an environmental sustainability plan for one hospital from 2008 to present, including best strategies, lessons learned, and what lies ahead of us in the new world of capping greenhouse gas emissions.

  7. A comparison of temporal and location-based sampling strategies for global positioning system-triggered electronic diaries.

    PubMed

    Törnros, Tobias; Dorn, Helen; Reichert, Markus; Ebner-Priemer, Ulrich; Salize, Hans-Joachim; Tost, Heike; Meyer-Lindenberg, Andreas; Zipf, Alexander

    2016-11-21

    Self-reporting is a well-established approach within the medical and psychological sciences. In order to avoid recall bias, i.e. past events being remembered inaccurately, the reports can be filled out on a smartphone in real-time and in the natural environment. This is often referred to as ambulatory assessment and the reports are usually triggered at regular time intervals. With this sampling scheme, however, rare events (e.g. a visit to a park or recreation area) are likely to be missed. When addressing the correlation between mood and the environment, it may therefore be beneficial to include participant locations within the ambulatory assessment sampling scheme. Based on the geographical coordinates, the database query system then decides if a self-report should be triggered or not. We simulated four different ambulatory assessment sampling schemes based on movement data (coordinates by minute) from 143 voluntary participants tracked for seven consecutive days. Two location-based sampling schemes incorporating the environmental characteristics (land use and population density) at each participant's location were introduced and compared to a time-based sampling scheme triggering a report on the hour as well as to a sampling scheme incorporating physical activity. We show that location-based sampling schemes trigger a report less often, but we obtain more unique trigger positions and a greater spatial spread in comparison to sampling strategies based on time and distance. Additionally, the location-based methods trigger significantly more often at rarely visited types of land use and less often outside the study region where no underlying environmental data are available.

  8. Evidences of landslide earthquake triggering due to self-excitation process

    NASA Astrophysics Data System (ADS)

    Bozzano, F.; Lenti, L.; Martino, Salvatore; Paciello, A.; Scarascia Mugnozza, G.

    2011-06-01

    The basin-like setting of stiff bedrock combined with pre-existing landslide masses can contribute to seismic amplifications in a wide frequency range (0-10 Hz) and induce a self-excitation process responsible for earthquake-triggered landsliding. Here, the self-excitation process is proposed to justify the far-field seismic trigger of the Cerda landslide (Sicily, Italy) which was reactivated by the 6th September 2002 Palermo earthquake ( M s = 5.4), about 50 km far from the epicentre. The landslide caused damage to farm houses, roads and aqueducts, close to the village of Cerda, and involved about 40 × 106 m3 of clay shales; the first ground cracks due to the landslide movement formed about 30 min after the main shock. A stress-strain dynamic numerical modelling, performed by FDM code FLAC 5.0, supports the notion that the combination of local geological setting and earthquake frequency content played a fundamental role in the landslide reactivation. Since accelerometric records of the triggering event are not available, dynamic equivalent inputs have been used for the numerical modelling. These inputs can be regarded as representative for the local ground shaking, having a PGA value up to 0.2 m/s2, which is the maximum expected in 475 years, according to the Italian seismic hazard maps. A 2D numerical modelling of the seismic wave propagation in the Cerda landslide area was also performed; it pointed out amplification effects due to both the structural setting of the stiff bedrock (at about 1 Hz) and the pre-existing landslide mass (in the range 3-6 Hz). The frequency peaks of the resulting amplification functions ( A( f)) fit well the H/ V spectral ratios from ambient noise and the H/ H spectral ratios to a reference station from earthquake records, obtained by in situ velocimetric measurements. Moreover, the Fourier spectra of earthquake accelerometric records, whose source and magnitude are consistent with the triggering event, show a main peak at about 1 Hz

  9. Predicting Trigger Bonds in Explosive Materials through Wiberg Bond Index Analysis.

    PubMed

    Harper, Lenora K; Shoaf, Ashley L; Bayse, Craig A

    2015-12-21

    Understanding the explosive decomposition pathways of high-energy-density materials (HEDMs) is important for developing compounds with improved properties. Rapid reaction rates make the detonation mechanisms of HEDMs difficult to understand, so computational tools are used to predict trigger bonds-weak bonds that break, leading to detonation. Wiberg bond indices (WBIs) have been used to compare bond densities in HEDMs to reference molecules to provide a relative scale for the bond strength to predict the activated bonds most likely to break to trigger an explosion. This analysis confirms that X-NO2 (X=N,C,O) bonds are trigger linkages in common HEDMs such as TNT, RDX and PETN, consistent with previous experimental and theoretical studies. Calculations on a small test set of substituted tetrazoles show that the assignment of the trigger bond depends upon the functionality of the material and that the relative weakening of the bond correlates with experimental impact sensitivities. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Migraine and triggers: Post hoc ergo propter hoc?

    PubMed Central

    Hoffmann, Jan; Recober, Ana

    2013-01-01

    The influence of environmental factors on the clinical manifestation of migraine has been a matter of extensive debate over the past decades. Migraineurs commonly report foods, alcohol, meteorologic or atmospheric changes, exposure to light, sounds, or odors, as factors that trigger or aggravate their migraine attacks. In the same way, physicians frequently follow this belief in their recommendations in how migraineurs may reduce their attack frequency, especially with regard to the consumption of certain food components. Interestingly, despite being such a common belief, most of the clinical studies have shown conflicting results. The aim of the review is to critically analyze clinical and pathophysiological facts that support or refute a correlation between certain environmental stimuli and the occurrence of migraine attacks. Given the substantial discrepancy between patients' reports and objective clinical data, the methodological difficulties of investigating the link between environmental factors and migraine are highlighted. PMID:23996725

  11. A context-intensive approach to imputation of missing values in data sets from networks of environmental monitors.

    PubMed

    Larsen, Lawrence C; Shah, Mena

    2016-01-01

    Although networks of environmental monitors are constantly improving through advances in technology and management, instances of missing data still occur. Many methods of imputing values for missing data are available, but they are often difficult to use or produce unsatisfactory results. I-Bot (short for "Imputation Robot") is a context-intensive approach to the imputation of missing data in data sets from networks of environmental monitors. I-Bot is easy to use and routinely produces imputed values that are highly reliable. I-Bot is described and demonstrated using more than 10 years of California data for daily maximum 8-hr ozone, 24-hr PM2.5 (particulate matter with an aerodynamic diameter <2.5 μm), mid-day average surface temperature, and mid-day average wind speed. I-Bot performance is evaluated by imputing values for observed data as if they were missing, and then comparing the imputed values with the observed values. In many cases, I-Bot is able to impute values for long periods with missing data, such as a week, a month, a year, or even longer. Qualitative visual methods and standard quantitative metrics demonstrate the effectiveness of the I-Bot methodology. Many resources are expended every year to analyze and interpret data sets from networks of environmental monitors. A large fraction of those resources is used to cope with difficulties due to the presence of missing data. The I-Bot method of imputing values for such missing data may help convert incomplete data sets into virtually complete data sets that facilitate the analysis and reliable interpretation of vital environmental data.

  12. Lowering Temperature is the Trigger for Glycogen Build-Up and Winter Fasting in Crucian Carp (Carassius carassius).

    PubMed

    Varis, Joonas; Haverinen, Jaakko; Vornanen, Matti

    2016-02-01

    Seasonal changes in physiology of vertebrate animals are triggered by environmental cues including temperature, day-length and oxygen availability. Crucian carp (Carassius carassius) tolerate prolonged anoxia in winter by using several physiological adaptations that are seasonally activated. This study examines which environmental cues are required to trigger physiological adjustments for winter dormancy in crucian carp. To this end, crucian carp were exposed to changing environmental factors under laboratory conditions: effects of declining water temperature, shortening day-length and reduced oxygen availability, separately and in different combinations, were examined on glycogen content and enzyme activities involved in feeding (alkaline phosphatase, AP) and glycogen metabolism (glycogen synthase, GyS; glycogen phosphorylase, GP). Lowering temperature induced a fall in activity of AP and a rise in glycogen content and rate of glycogen synthesis. Relative mass of the liver, and glycogen concentration of liver, muscle and brain increased with lowering temperature. Similarly activity of GyS in muscle and expression of GyS transcripts in brain were up-regulated by lowering temperature. Shortened day-length and oxygen availability had practically no effects on measured variables. We conclude that lowering temperature is the main trigger in preparation for winter anoxia in crucian carp.

  13. Permanently enhanced dynamic triggering probabilities as evidenced by two M ≥ 7.5 earthquakes

    USGS Publications Warehouse

    Gomberg, Joan S.

    2013-01-01

    The 2012 M7.7 Haida Gwaii earthquake radiated waves that likely dynamically triggered the 2013M7.5 Craig earthquake, setting two precedents. First, the triggered earthquake is the largest dynamically triggered shear failure event documented to date. Second, the events highlight a connection between geologic structure, sedimentary troughs that act as waveguides, and triggering probability. The Haida Gwaii earthquake excited extraordinarily large waves within and beyond the Queen Charlotte Trough, which propagated well into mainland Alaska and likely triggering the Craig earthquake along the way. Previously, focusing and associated dynamic triggering have been attributed to unpredictable source effects. This case suggests that elevated dynamic triggering probabilities may exist along the many structures where sedimentary troughs overlie major faults, such as subduction zones’ accretionary prisms and transform faults’ axial valleys. Although data are sparse, I find no evidence of accelerating seismic activity in the vicinity of the Craig rupture between it and the Haida Gwaii earthquake.

  14. Triggered creep as a possible mechanism for delayed dynamic triggering of tremor and earthquakes

    USGS Publications Warehouse

    Shelly, David R.; Peng, Zhigang; Hill, David P.; Aiken, Chastity

    2011-01-01

    The passage of radiating seismic waves generates transient stresses in the Earth's crust that can trigger slip on faults far away from the original earthquake source. The triggered fault slip is detectable in the form of earthquakes and seismic tremor. However, the significance of these triggered events remains controversial, in part because they often occur with some delay, long after the triggering stress has passed. Here we scrutinize the location and timing of tremor on the San Andreas fault between 2001 and 2010 in relation to distant earthquakes. We observe tremor on the San Andreas fault that is initiated by passing seismic waves, yet migrates along the fault at a much slower velocity than the radiating seismic waves. We suggest that the migrating tremor records triggered slow slip of the San Andreas fault as a propagating creep event. We find that the triggered tremor and fault creep can be initiated by distant earthquakes as small as magnitude 5.4 and can persist for several days after the seismic waves have passed. Our observations of prolonged tremor activity provide a clear example of the delayed dynamic triggering of seismic events. Fault creep has been shown to trigger earthquakes, and we therefore suggest that the dynamic triggering of prolonged fault creep could provide a mechanism for the delayed triggering of earthquakes. ?? 2011 Macmillan Publishers Limited. All rights reserved.

  15. Triggers of oral lichen planus flares and the potential role of trigger avoidance in disease management.

    PubMed

    Chen, Hannah X; Blasiak, Rachel; Kim, Edwin; Padilla, Ricardo; Culton, Donna A

    2017-09-01

    Many patients with oral lichen planus (OLP) report triggers of flares, some of which overlap with triggers of other oral diseases, including oral allergy syndrome and oral contact dermatitis. The purpose of this study was to evaluate the prevalence of commonly reported triggers of OLP flares, their overlap with triggers of other oral diseases, and the potential role of trigger avoidance as a management strategy. Questionnaire-based survey of 51 patients with biopsy-proven lichen planus with oral involvement seen in an academic dermatology specialty clinic and/or oral pathology clinic between June 2014 and June 2015. Of the participants, 94% identified at least one trigger of their OLP flares. Approximately half of the participants (51%) reported at least one trigger that overlapped with known triggers of oral allergy syndrome, and 63% identified at least one trigger that overlapped with known triggers of oral contact dermatitis. Emotional stress was the most commonly reported trigger (77%). Regarding avoidance, 79% of the study participants reported avoiding their known triggers in daily life. Of those who actively avoided triggers, 89% reported an improvement in symptoms and 70% reported a decrease in the frequency of flares. Trigger identification and avoidance can play a potentially effective role in the management of OLP. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Natural experimentation is a challenging method for identifying headache triggers.

    PubMed

    Houle, Timothy T; Turner, Dana P

    2013-04-01

    In this study, we set out to determine whether individual headache sufferers can learn about the potency of their headache triggers (causes) using only natural experimentation. Headache patients naturally use the covariation of the presence-absence of triggers with headache attacks to assess the potency of triggers. The validity of this natural experimentation has never been investigated. A companion study has proposed 3 assumptions that are important for assigning causal status to triggers. This manuscript examines one of these assumptions, constancy in trigger presentation, using real-world conditions. The similarity of day-to-day weather conditions over 4 years, as well as the similarity of ovarian hormones and perceived stress over a median of 89 days in 9 regularly cycling headache sufferers, was examined using several available time series. An arbitrary threshold of 90% similarity using Gower's index identified similar days for comparison. The day-to-day variability in just these 3 headache triggers is substantial enough that finding 2 naturally similar days for which to contrast the effect of a fourth trigger (eg, drinking wine vs not drinking wine) will only infrequently occur. Fluctuations in weather patterns resulted in a median of 2.3 days each year that were similar (range 0-27.4). Considering fluctuations in stress patterns and ovarian hormones, only 1.5 days/month (95% confidence interval 1.2-2.9) and 2.0 days/month (95% confidence interval 1.9-2.2), respectively, met our threshold for similarity. Although assessing the personal causes of headache is an age-old endeavor, the great many candidate triggers exhibit variability that may prevent sound conclusions without assistance from formal experimentation or statistical balancing. © 2013 American Headache Society.

  17. Natural experimentation is a challenging method for identifying headache triggers

    PubMed Central

    Houle, Timothy T.; Turner, Dana P.

    2015-01-01

    Objective In this study we set out to determine whether individual headache sufferers can learn about the potency of their headache triggers (causes) using only natural experimentation. Background Headache patients naturally use the covariation of the presence-absence of triggers with headache attacks to assess the potency of triggers. The validity of this natural experimentation has never been investigated. A companion study has proposed three assumptions that are important for assigning causal status to triggers. This manuscript examines one of these assumptions, constancy in trigger presentation, using real-world conditions. Methods The similarity of day-to-day weather conditions over four years, as well as the similarity of ovarian hormones and perceived stress over a median of 89 days in nine regularly cycling headache sufferers were examined using several available time-series. An arbitrary threshold of 90% similarity using Gower's index identified similar days for comparison. Results The day-to-day variability in just these three headache triggers is substantial enough that finding two naturally similar days for which to contrast the effect of a fourth trigger (e.g., drinking wine versus not drinking wine) will only infrequently occur. Fluctuations in weather patterns resulted in a median of 2.3 days each year that were similar (range: 0 to 27.4). Considering fluctuations in stress patterns and ovarian hormones, only 1.5 days/month (95%CI: 1.2 to 2.9) and 2.0 days/month (95%CI: 1.9 to 2.2), respectively, met our threshold for similarity.. Conclusion Although assessing the personal causes of headache is an age-old endeavor, the great many candidate triggers exhibit variability that may prevent sound conclusions without assistance from formal experimentation or statistical balancing. PMID:23534852

  18. Triggering of repeating earthquakes in central California

    USGS Publications Warehouse

    Wu, Chunquan; Gomberg, Joan; Ben-Naim, Eli; Johnson, Paul

    2014-01-01

    Dynamic stresses carried by transient seismic waves have been found capable of triggering earthquakes instantly in various tectonic settings. Delayed triggering may be even more common, but the mechanisms are not well understood. Catalogs of repeating earthquakes, earthquakes that recur repeatedly at the same location, provide ideal data sets to test the effects of transient dynamic perturbations on the timing of earthquake occurrence. Here we employ a catalog of 165 families containing ~2500 total repeating earthquakes to test whether dynamic perturbations from local, regional, and teleseismic earthquakes change recurrence intervals. The distance to the earthquake generating the perturbing waves is a proxy for the relative potential contributions of static and dynamic deformations, because static deformations decay more rapidly with distance. Clear changes followed the nearby 2004 Mw6 Parkfield earthquake, so we study only repeaters prior to its origin time. We apply a Monte Carlo approach to compare the observed number of shortened recurrence intervals following dynamic perturbations with the distribution of this number estimated for randomized perturbation times. We examine the comparison for a series of dynamic stress peak amplitude and distance thresholds. The results suggest a weak correlation between dynamic perturbations in excess of ~20 kPa and shortened recurrence intervals, for both nearby and remote perturbations.

  19. The Effect of Priming with Photographs of Environmental Settings on Walking Speed in an Outdoor Environment.

    PubMed

    Franěk, Marek; Režný, Lukáš

    2017-01-01

    This study examined the effect of priming with photographs of various environmental settings on the speed of a subsequent outdoor walk in an urban environment. Either photographs of urban greenery, conifer forests, or shopping malls were presented or no prime was employed. Three experiments were conducted ( N = 126, N = 88, and N = 121). After being exposed to the priming or no-priming conditions, the participants were asked to walk along an urban route 1.9 km long with vegetation and mature trees (Experiment 1, Experiment 3) or along a route in a modern suburb (Experiment 2). In accord with the concept of approach-avoidance behavior, it was expected that priming with photographs congruent with the environmental setting of the walking route would result in slower walking speed. Conversely, priming with photographs incongruent with the environmental setting should result in faster walking speed. The results showed that priming with the photographs with vegetation caused a decrease in overall walking speed on the route relative to other experimental conditions. However, priming with incongruent primes did not lead to a significant increase in walking speed. In all experimental conditions, the slowest walking speed was found in sections with the highest natural character. The results are explained in terms of congruency between the prime and the environment, as well as by the positive psychological effects of viewing nature.

  20. The Effect of Priming with Photographs of Environmental Settings on Walking Speed in an Outdoor Environment

    PubMed Central

    Franěk, Marek; Režný, Lukáš

    2017-01-01

    This study examined the effect of priming with photographs of various environmental settings on the speed of a subsequent outdoor walk in an urban environment. Either photographs of urban greenery, conifer forests, or shopping malls were presented or no prime was employed. Three experiments were conducted (N = 126, N = 88, and N = 121). After being exposed to the priming or no-priming conditions, the participants were asked to walk along an urban route 1.9 km long with vegetation and mature trees (Experiment 1, Experiment 3) or along a route in a modern suburb (Experiment 2). In accord with the concept of approach-avoidance behavior, it was expected that priming with photographs congruent with the environmental setting of the walking route would result in slower walking speed. Conversely, priming with photographs incongruent with the environmental setting should result in faster walking speed. The results showed that priming with the photographs with vegetation caused a decrease in overall walking speed on the route relative to other experimental conditions. However, priming with incongruent primes did not lead to a significant increase in walking speed. In all experimental conditions, the slowest walking speed was found in sections with the highest natural character. The results are explained in terms of congruency between the prime and the environment, as well as by the positive psychological effects of viewing nature. PMID:28184208

  1. Systematic Detection of Remotely Triggered Seismicity in Africa Following Recent Large Earthquakes

    NASA Astrophysics Data System (ADS)

    Ayorinde, A. O.; Peng, Z.; Yao, D.; Bansal, A. R.

    2016-12-01

    It is well known that large distant earthquakes can trigger micro-earthquakes/tectonic tremors during or immediately following their surface waves. Globally, triggered earthquakes have been mostly found in active plate boundary regions. It is not clear whether they could occur within stable intraplate regions in Africa as well as the active East African Rift Zone. In this study we conduct a systematic study of remote triggering in Africa following recent large earthquakes, including the 2004 Mw9.1 Sumatra and 2012 Mw8.6 Indian Ocean earthquakes. In particular, the 2012 Indian Ocean earthquake is the largest known strike slip earthquake and has triggered a global increase of magnitude larger than 5.5 earthquakes as well as numerous micro-earthquakes/tectonic tremors around the world. The entire Africa region was examined for possible remotely triggered seismicity using seismic data downloaded from the Incorporated Research Institutes for Seismology (IRIS) Data Management Center (DMC) and GFZ German Research Center for Geosciences. We apply a 5-Hz high-pass-filter to the continuous waveforms and visually identify high-frequency signals during and immediately after the large amplitude surface waves. Spectrograms are computed as additional tools to identify triggered seismicities and we further confirm them by statistical analysis comparing the high-frequency signals before and after the distant mainshocks. So far we have identified possible triggered seismicity in Botswana and northern Madagascar. This study could help to understand dynamic triggering in diverse tectonic settings of the African continent.

  2. Optimization of a simultaneous dual-isotope 201Tl/123I-MIBG myocardial SPECT imaging protocol with a CZT camera for trigger zone assessment after myocardial infarction for routine clinical settings: Are delayed acquisition and scatter correction necessary?

    PubMed

    D'estanque, Emmanuel; Hedon, Christophe; Lattuca, Benoît; Bourdon, Aurélie; Benkiran, Meriem; Verd, Aurélie; Roubille, François; Mariano-Goulart, Denis

    2017-08-01

    Dual-isotope 201 Tl/ 123 I-MIBG SPECT can assess trigger zones (dysfunctions in the autonomic nervous system located in areas of viable myocardium) that are substrate for ventricular arrhythmias after STEMI. This study evaluated the necessity of delayed acquisition and scatter correction for dual-isotope 201 Tl/ 123 I-MIBG SPECT studies with a CZT camera to identify trigger zones after revascularization in patients with STEMI in routine clinical settings. Sixty-nine patients were prospectively enrolled after revascularization to undergo 201 Tl/ 123 I-MIBG SPECT using a CZT camera (Discovery NM 530c, GE). The first acquisition was a single thallium study (before MIBG administration); the second and the third were early and late dual-isotope studies. We compared the scatter-uncorrected and scatter-corrected (TEW method) thallium studies with the results of magnetic resonance imaging or transthoracic echography (reference standard) to diagnose myocardial necrosis. Summed rest scores (SRS) were significantly higher in the delayed MIBG studies than the early MIBG studies. SRS and necrosis surface were significantly higher in the delayed thallium studies with scatter correction than without scatter correction, leading to less trigger zone diagnosis for the scatter-corrected studies. Compared with the scatter-uncorrected studies, the late thallium scatter-corrected studies provided the best diagnostic values for myocardial necrosis assessment. Delayed acquisitions and scatter-corrected dual-isotope 201 Tl/ 123 I-MIBG SPECT acquisitions provide an improved evaluation of trigger zones in routine clinical settings after revascularization for STEMI.

  3. The Topo-trigger: a new concept of stereo trigger system for imaging atmospheric Cherenkov telescopes

    NASA Astrophysics Data System (ADS)

    López-Coto, R.; Mazin, D.; Paoletti, R.; Blanch Bigas, O.; Cortina, J.

    2016-04-01

    Imaging atmospheric Cherenkov telescopes (IACTs) such as the Major Atmospheric Gamma-ray Imaging Cherenkov (MAGIC) telescopes endeavor to reach the lowest possible energy threshold. In doing so the trigger system is a key element. Reducing the trigger threshold is hampered by the rapid increase of accidental triggers generated by ambient light (the so-called Night Sky Background NSB). In this paper we present a topological trigger, dubbed Topo-trigger, which rejects events on the basis of their relative orientation in the telescope cameras. We have simulated and tested the trigger selection algorithm in the MAGIC telescopes. The algorithm was tested using MonteCarlo simulations and shows a rejection of 85% of the accidental stereo triggers while preserving 99% of the gamma rays. A full implementation of this trigger system would achieve an increase in collection area between 10 and 20% at the energy threshold. The analysis energy threshold of the instrument is expected to decrease by ~ 8%. The selection algorithm was tested on real MAGIC data taken with the current trigger configuration and no γ-like events were found to be lost.

  4. Causality and headache triggers

    PubMed Central

    Turner, Dana P.; Smitherman, Todd A.; Martin, Vincent T.; Penzien, Donald B.; Houle, Timothy T.

    2013-01-01

    Objective The objective of this study was to explore the conditions necessary to assign causal status to headache triggers. Background The term “headache trigger” is commonly used to label any stimulus that is assumed to cause headaches. However, the assumptions required for determining if a given stimulus in fact has a causal-type relationship in eliciting headaches have not been explicated. Methods A synthesis and application of Rubin’s Causal Model is applied to the context of headache causes. From this application the conditions necessary to infer that one event (trigger) causes another (headache) are outlined using basic assumptions and examples from relevant literature. Results Although many conditions must be satisfied for a causal attribution, three basic assumptions are identified for determining causality in headache triggers: 1) constancy of the sufferer; 2) constancy of the trigger effect; and 3) constancy of the trigger presentation. A valid evaluation of a potential trigger’s effect can only be undertaken once these three basic assumptions are satisfied during formal or informal studies of headache triggers. Conclusions Evaluating these assumptions is extremely difficult or infeasible in clinical practice, and satisfying them during natural experimentation is unlikely. Researchers, practitioners, and headache sufferers are encouraged to avoid natural experimentation to determine the causal effects of headache triggers. Instead, formal experimental designs or retrospective diary studies using advanced statistical modeling techniques provide the best approaches to satisfy the required assumptions and inform causal statements about headache triggers. PMID:23534872

  5. Photon-triggered nanowire transistors

    NASA Astrophysics Data System (ADS)

    Kim, Jungkil; Lee, Hoo-Cheol; Kim, Kyoung-Ho; Hwang, Min-Soo; Park, Jin-Sung; Lee, Jung Min; So, Jae-Pil; Choi, Jae-Hyuck; Kwon, Soon-Hong; Barrelet, Carl J.; Park, Hong-Gyu

    2017-10-01

    Photon-triggered electronic circuits have been a long-standing goal of photonics. Recent demonstrations include either all-optical transistors in which photons control other photons or phototransistors with the gate response tuned or enhanced by photons. However, only a few studies report on devices in which electronic currents are optically switched and amplified without an electrical gate. Here we show photon-triggered nanowire (NW) transistors, photon-triggered NW logic gates and a single NW photodetection system. NWs are synthesized with long crystalline silicon (CSi) segments connected by short porous silicon (PSi) segments. In a fabricated device, the electrical contacts on both ends of the NW are connected to a single PSi segment in the middle. Exposing the PSi segment to light triggers a current in the NW with a high on/off ratio of >8 × 106. A device that contains two PSi segments along the NW can be triggered using two independent optical input signals. Using localized pump lasers, we demonstrate photon-triggered logic gates including AND, OR and NAND gates. A photon-triggered NW transistor of diameter 25 nm with a single 100 nm PSi segment requires less than 300 pW of power. Furthermore, we take advantage of the high photosensitivity and fabricate a submicrometre-resolution photodetection system. Photon-triggered transistors offer a new venue towards multifunctional device applications such as programmable logic elements and ultrasensitive photodetectors.

  6. Photon-triggered nanowire transistors.

    PubMed

    Kim, Jungkil; Lee, Hoo-Cheol; Kim, Kyoung-Ho; Hwang, Min-Soo; Park, Jin-Sung; Lee, Jung Min; So, Jae-Pil; Choi, Jae-Hyuck; Kwon, Soon-Hong; Barrelet, Carl J; Park, Hong-Gyu

    2017-10-01

    Photon-triggered electronic circuits have been a long-standing goal of photonics. Recent demonstrations include either all-optical transistors in which photons control other photons or phototransistors with the gate response tuned or enhanced by photons. However, only a few studies report on devices in which electronic currents are optically switched and amplified without an electrical gate. Here we show photon-triggered nanowire (NW) transistors, photon-triggered NW logic gates and a single NW photodetection system. NWs are synthesized with long crystalline silicon (CSi) segments connected by short porous silicon (PSi) segments. In a fabricated device, the electrical contacts on both ends of the NW are connected to a single PSi segment in the middle. Exposing the PSi segment to light triggers a current in the NW with a high on/off ratio of >8 × 10 6 . A device that contains two PSi segments along the NW can be triggered using two independent optical input signals. Using localized pump lasers, we demonstrate photon-triggered logic gates including AND, OR and NAND gates. A photon-triggered NW transistor of diameter 25 nm with a single 100 nm PSi segment requires less than 300 pW of power. Furthermore, we take advantage of the high photosensitivity and fabricate a submicrometre-resolution photodetection system. Photon-triggered transistors offer a new venue towards multifunctional device applications such as programmable logic elements and ultrasensitive photodetectors.

  7. Can environmental conditions trigger cyanobacterial surfaces and following carbonate formation: implication for biomineralization and biotechnology

    NASA Astrophysics Data System (ADS)

    Paulo, C.; Dittrich, M.; Zhu, T.

    2015-12-01

    In this presentation we will give an overview what kind of the factors may trigger carbonate formations at the cell surfaces under a variety of environmental conditions. As examples, we will present the results from our recent studies on formation of calcium carbonates, dolomites and bio-cements. The extracellular polymeric substances (EPS) in the Synechococcuscell envelope are recognized key players in the nucleation of carbonates in marine and freshwater environments. Yet, little is known about a nutrient contents control over the molecular composition of Synechococcus cell envelope, and consequently, biomineralization. In the first study, we investigated how a variation of the phosphorus (P) in the growth media can lead to changes in the surface reactivity of the cells and impact their ability to form carbonates. The objective of the second study is to gain insights into the spatial distribution of cyanobacterial EPS and dolomite from different sediment layers of Khor Al-Adaid sabkha (Qatar). Here, we characterized microbial mats on molecular level in respect of organic and inorganic components using in-situ 2D Raman spectroscopy and Atomic Force Microscopy (AFM) were used. Additionally, 2D chemical maps of sediment layers documented spectral characterizations of minerals and organic matter of microbial origins at high spatial resolution. Finally, we will show the results from the experiments with auto-phototrophic cyanobacteria Gloeocapsa PCC73106, which habitat on the monument surfaces, towards its application for bio-concrete, a product of microbial carbonate precipitation. We studied the biomineralization in biofilm forming Gloeocapsa PCC73106 on the concrete surface as a pre-requirement for microbial carbonate precipitation. Biomineralization on the concrete surface by live cells and killed cells were compared with that under the abiotic condition. Our experiments allow us to conclude that environmental conditions play a significant role in the control of

  8. Triggers of the HSP70 stress response: environmental responses and laboratory manipulation in an Antarctic marine invertebrate (Nacella concinna)

    PubMed Central

    Peck, Lloyd S.

    2009-01-01

    The Antarctic limpet, Nacella concinna, exhibits the classical heat shock response, with up-regulation of duplicated forms of the inducible heat shock protein 70 (HSP70) gene in response to experimental manipulation of seawater temperatures. However, this response only occurs in the laboratory at temperatures well in excess of any experienced in the field. Subsequent environmental sampling of inter-tidal animals also showed up-regulation of these genes, but at temperature thresholds much lower than those required to elicit a response in the laboratory. It was hypothesised that this was a reflection of the complexity of the stresses encountered in the inter-tidal region. Here, we describe a further series of experiments comprising both laboratory manipulation and environmental sampling of N. concinna. We investigate the expression of HSP70 gene family members (HSP70A, HSP70B, GRP78 and HSC70) in response to a further suite of environmental stressors: seasonal and experimental cold, freshwater, desiccation, chronic heat and periodic emersion. Lowered temperatures (−1.9°C and −1.6°C), generally produced a down-regulation of all HSP70 family members, with some up-regulation of HSC70 when emerging from the winter period and increasing sea temperatures. There was no significant response to freshwater immersion. In response to acute and chronic heat treatments plus simulated tidal cycles, the data showed a clear pattern. HSP70A showed a strong but very short-term response to heat whilst the duplicated HSP70B also showed heat to be a trigger, but had a more sustained response to complex stresses. GRP78 expression indicates that it was acting as a generalised stress response under the experimental conditions described here. HSC70 was the major chaperone invoked in response to long-term stresses of varying types. These results provide intriguing clues not only to the complexity of HSP70 gene expression in response to environmental change but also insights into the

  9. Triggers of the HSP70 stress response: environmental responses and laboratory manipulation in an Antarctic marine invertebrate (Nacella concinna).

    PubMed

    Clark, Melody S; Peck, Lloyd S

    2009-11-01

    The Antarctic limpet, Nacella concinna, exhibits the classical heat shock response, with up-regulation of duplicated forms of the inducible heat shock protein 70 (HSP70) gene in response to experimental manipulation of seawater temperatures. However, this response only occurs in the laboratory at temperatures well in excess of any experienced in the field. Subsequent environmental sampling of inter-tidal animals also showed up-regulation of these genes, but at temperature thresholds much lower than those required to elicit a response in the laboratory. It was hypothesised that this was a reflection of the complexity of the stresses encountered in the inter-tidal region. Here, we describe a further series of experiments comprising both laboratory manipulation and environmental sampling of N. concinna. We investigate the expression of HSP70 gene family members (HSP70A, HSP70B, GRP78 and HSC70) in response to a further suite of environmental stressors: seasonal and experimental cold, freshwater, desiccation, chronic heat and periodic emersion. Lowered temperatures (-1.9 degrees C and -1.6 degrees C), generally produced a down-regulation of all HSP70 family members, with some up-regulation of HSC70 when emerging from the winter period and increasing sea temperatures. There was no significant response to freshwater immersion. In response to acute and chronic heat treatments plus simulated tidal cycles, the data showed a clear pattern. HSP70A showed a strong but very short-term response to heat whilst the duplicated HSP70B also showed heat to be a trigger, but had a more sustained response to complex stresses. GRP78 expression indicates that it was acting as a generalised stress response under the experimental conditions described here. HSC70 was the major chaperone invoked in response to long-term stresses of varying types. These results provide intriguing clues not only to the complexity of HSP70 gene expression in response to environmental change but also insights

  10. ELECTRONIC TRIGGER CIRCUIT

    DOEpatents

    Russell, J.A.G.

    1958-01-01

    An electronic trigger circuit is described of the type where an output pulse is obtained only after an input voltage has cqualed or exceeded a selected reference voltage. In general, the invention comprises a source of direct current reference voltage in series with an impedance and a diode rectifying element. An input pulse of preselected amplitude causes the diode to conduct and develop a signal across the impedance. The signal is delivered to an amplifier where an output pulse is produced and part of the output is fed back in a positive manner to the diode so that the amplifier produces a steep wave front trigger pulsc at the output. The trigger point of the described circuit is not subject to variation due to the aging, etc., of multi-electrode tabes, since the diode circuit essentially determines the trigger point.

  11. Environmental setting of the Yellowstone River basin, Montana, North Dakota, and Wyoming

    USGS Publications Warehouse

    Zelt, Ronald B.; Boughton, G.K.; Miller, K.A.; Mason, J.P.; Gianakos, L.M.

    1999-01-01

    Natural and anthropogenic factors influence water-quality conditions in the Yellowstone River Basin. Physiography parallels the structural geologic setting that is generally composed of several uplifts and structural basins. Contrasts in climate and vegetation reflect topographic controls and the midcontinental location of the study unit. Surface-water hydrology reflects water surpluses in mountainous areas that are dominated by snowmelt runoff, and arid to semiarid conditions in the plains that are dissected by typically irrigated valleys in the remainder of the study unit. Principal shallow aquifers are Tertiary sandstones and unconsolidated Quaternary deposits. Human population, though sparsely distributed in general, is growing most rapidly in a few urban centers and resort areas, mostly in the northwestern part of the basin. Land use is areally dominated by grazing in the basins and plains and economically dominated by mineral-extraction activities. Forests are the dominant land cover in mountainous areas. Cropland is a major land use in principal stream valleys. Water use is dominated by irrigated agriculture overall, but mining and public-supply facilities are major users of ground water. Coal and hydrocarbon production and reserves distinguish the Yellowstone River Basin as a principal energy-minerals resources region. Current metallic ore production or reserves are nationally significant for platinum-group elements and chromium.The study unit was subdivided as an initial environmental stratification for use in designing the National Water-Quality Assessment Program investigation that began in 1997. Ecoregions, geologic groups, mineral-resource areas, and general land-cover and land-use categories were used in combination to define 18 environmental settings in the Yellowstone River Basin. It is expected that these different settings will be reflected in differing water-quality or aquatic-ecological characteristics.

  12. Triggering of frequent turbidity currents in Monterey Canyon and the role of antecedent conditioning

    NASA Astrophysics Data System (ADS)

    Clare, M. A.; Rosenberger, K. J.; Talling, P.; Barry, J.; Maier, K. L.; Parsons, D. R.; Simmons, S.; Gales, J. A.; Gwiazda, R.; McGann, M.; Paull, C. K.

    2017-12-01

    Turbidity currents pose a hazard to seafloor infrastructure, deliver organic carbon and nutrients to deep-sea communities, and form economically important deposits. Thus, determining the tempo of turbidity current activity and whether different triggers result in different flow modes is important. Identification of specific triggers is challenging, however, because most studies of turbidity currents are based on their deposits. New direct monitoring of flows and environmental conditions provides the necessary temporal constraints to identify triggering mechanisms. The Coordinated Canyon Experiment (CCE) in Monterey Canyon, offshore California is the most ambitious attempt yet to measure turbidity flows and their triggers. The CCE provides precise constraint on flow timing, initiation, and potential triggers based on measurements at 7 different instrumented moorings and 2 metocean buoys. Fifteen turbidity flows were measured in 18 months; with recorded velocities >8 m/s and run-outs of up to 50 km. Presence of live estuarine foraminifera within moored sediment traps suggests that that flows originated in water depths of <10 m, but it is unclear specifically how these flows were triggered. Turbidity currents are thought to be triggered by processes including earthquakes, river floods and storm waves. Here we analyse seismicity, local river discharge, internal tides, wave height, direction and period data. We identify no clear control of any of these individual variables on flow timing. None of the recorded earthquakes (

  13. A Review of Video Triggers and Video Production in Higher Education and Continuing Education PBL Settings

    ERIC Educational Resources Information Center

    Rasi, Päivi M.; Poikela, Sari

    2016-01-01

    Higher education faces the challenges of bridging education and authentic work. In addition, it needs to respond to the highly multimodal and participatory communication and content creation practices, preferences, and cultures of present and future students. The aim of our article is to discuss how the use of video triggers and video production…

  14. Environmental contaminants in food. Volume II-part a: working papers. I. Priority setting of toxic substances for guiding monitoring programs. II. Five case studies of environmental food contamination

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    This volume contains working papers written for Office of Technology Assessment (OTA) to assist in preparation of the report Environmental Contaminants in Food. The contents include: (1) Priority setting of toxic substances for guiding monitoring programs; and (2) Five case studies of environmental food contamination.

  15. AMY trigger system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sakai, Yoshihide

    1989-04-01

    A trigger system of the AMY detector at TRISTAN e{sup +}e{sup -} collider is described briefly. The system uses simple track segment and shower cluster counting scheme to classify events to be triggered. It has been operating successfully since 1987.

  16. Methods to characterize environmental settings of stream and groundwater sampling sites for National Water-Quality Assessment

    USGS Publications Warehouse

    Nakagaki, Naomi; Hitt, Kerie J.; Price, Curtis V.; Falcone, James A.

    2012-01-01

    Characterization of natural and anthropogenic features that define the environmental settings of sampling sites for streams and groundwater, including drainage basins and groundwater study areas, is an essential component of water-quality and ecological investigations being conducted as part of the U.S. Geological Survey's National Water-Quality Assessment program. Quantitative characterization of environmental settings, combined with physical, chemical, and biological data collected at sampling sites, contributes to understanding the status of, and influences on, water-quality and ecological conditions. To support studies for the National Water-Quality Assessment program, a geographic information system (GIS) was used to develop a standard set of methods to consistently characterize the sites, drainage basins, and groundwater study areas across the nation. This report describes three methods used for characterization-simple overlay, area-weighted areal interpolation, and land-cover-weighted areal interpolation-and their appropriate applications to geographic analyses that have different objectives and data constraints. In addition, this document records the GIS thematic datasets that are used for the Program's national design and data analyses.

  17. Changes in Mobility of Children with Cerebral Palsy over Time and across Environmental Settings

    ERIC Educational Resources Information Center

    Tieman, Beth L.; Palisano, Robert J.; Gracely, Edward J.; Rosenbaum, Peter L.; Chiarello, Lisa A.; O'Neil, Margaret E.

    2004-01-01

    This study examined changes in mobility methods of children with cerebral palsy (CP) over time and across environmental settings. Sixty-two children with CP, ages 6-14 years and classified as levels II-IV on the Gross Motor Function Classification System, were randomly selected from a larger data base and followed for three to four years. On each…

  18. Transformative environmental governance

    EPA Science Inventory

    Transformative governance is an approach to environmental governance that has the capacity to respond to, manage, and trigger regime shifts in coupled social-ecological systems (SESs) at multiple scales. The goal of transformative governance is to actively shift degraded SESs to ...

  19. AMPLITUDE DISCRIMINATOR HAVING SEPARATE TRIGGERING AND RECOVERY CONTROLS UTILIZING AUTOMATIC TRIGGERING

    DOEpatents

    Chase, R.L.

    1962-01-23

    A transistorized amplitude discriminator circuit is described in which the initial triggering sensitivity and the recovery threshold are separately adjustable in a convenient manner. The discriminator is provided with two independent bias components, one of which is for circuit hysteresis (recovery) and one of which is for trigger threshold level. A switching circuit is provided to remove the second bias component upon activation of the trigger so that the recovery threshold is always at the point where the trailing edge of the input signal pulse goes through zero or other desired value. (AEC)

  20. ? PID output-feedback control under event-triggered protocol

    NASA Astrophysics Data System (ADS)

    Zhao, Di; Wang, Zidong; Ding, Derui; Wei, Guoliang; Alsaadi, Fuad E.

    2018-07-01

    This paper is concerned with the ? proportional-integral-derivative (PID) output-feedback control problem for a class of linear discrete-time systems under event-triggered protocols. The controller and the actuators are connected through a communication network of limited bandwidth, and an event-triggered communication mechanism is adopted to decide when a certain control signal should be transmitted to the respective actuator. Furthermore, a novel PID output-feedback controller is designed where the accumulative sum-loop (the counterpart to the integral-loop in the continues-time setting) operates on a limited time-window with hope to mitigate the effect from the past measurement data. The main objective of the problem under consideration is to design a desired PID controller such that the closed-loop system is exponentially stable and the prescribed ? disturbance rejection attenuation level is guaranteed under event-triggered protocols. By means of the Lyapunov stability theory combined with the orthogonal decomposition, sufficient conditions are established under which the addressed PID controller design problem is recast into a linear convex optimization one that can be easily solved via available software packages. Finally, a simulation example is exploited to illustrate the usefulness and effectiveness of the established control scheme.

  1. The NA62 trigger system

    NASA Astrophysics Data System (ADS)

    Krivda, M.; NA62 Collaboration

    2013-08-01

    The main aim of the NA62 experiment (NA62 Technical Design Report, [1]) is to study ultra-rare Kaon decays. In order to select rare events over the overwhelming background, central systems with high-performance, high bandwidth, flexibility and configurability are necessary, that minimize dead time while maximizing data collection reliability. The NA62 experiment consists of 12 sub-detector systems and several trigger and control systems, for a total channel count of less than 100,000. The GigaTracKer (GTK) has the largest number of channels (54,000), and the Liquid Krypton (LKr) calorimeter shares with it the largest raw data rate (19 GB/s). The NA62 trigger system works with 3 trigger levels. The first trigger level is based on a hardware central trigger unit, so-called L0 Trigger Processor (L0TP), and Local Trigger Units (LTU), which are all located in the experimental cavern. Other two trigger levels are based on software, and done with a computer farm located on surface. The L0TP receives information from triggering sub-detectors asynchronously via Ethernet; it processes the information, and then transmits a final trigger decision synchronously to each sub-detector through the Trigger and Timing Control (TTC) system. The interface between L0TP and the TTC system, which is used for trigger and clock distribution, is provided by the Local Trigger Unit board (LTU). The LTU can work in two modes: global and stand-alone. In the global mode, the LTU provides an interface between L0TP and TTC system. In the stand-alone mode, the LTU can fully emulate L0TP and so provides an independent way for each sub-detector for testing or calibration purposes. In addition to the emulation functionality, a further functionality is implemented that allows to synchronize the clock of the LTU with the L0TP and the TTC system. For testing and debugging purposes, a Snap Shot Memory (SSM) interface is implemented, that can work

  2. Analyzing the Possibility of Dynamic Earthquake Triggering in Socorro, New Mexico

    NASA Astrophysics Data System (ADS)

    Morton, E.; Bilek, S. L.

    2011-12-01

    The release of energy during an earthquake changes the stress state and seismicity both locally and remotely. Far-field stress changes can lead to triggered earthquakes coinciding with the arrival of the surface waves. This dynamic triggering is found to occur in a variety of tectonic settings, but in particular magmatic regions. Here we test whether the Socorro Magma Body region in central New Mexico hosts triggered seismicity. Preliminary inspection of continuous network data in central New Mexico suggested a local triggered event with the passage of surface waves from an MW 6.9 event in 2009. For a more comprehensive view, we examine data from 379 earthquakes MW ≥ 6.0 between January 15, 2008 to March 13, 2010 recorded on the EarthScope USArray Transportable Network stations located within New Mexico and providing more dense coverage for better detectability. Waveforms from twenty EarthScope stations were windowed around the time of the large event, high-pass filtered at 5 Hz to remove low frequency signals and analyzed to detect high frequency triggered local earthquakes. For each possible trigger detected, waveforms from nine short-period stations in the Socorro Seismic Network were added to aid in locating the events. In the time period analyzed, twelve triggered events were detected. Only one of these events, on August 30, 2009, corresponded to the arrival of surface waves, occurring about a minute after their arrival. The majority of the triggered events occur well after the arrival of the surface waves, indicating that they are either independent of the main shock or the result of delayed dynamic triggering. Delayed dynamic triggering can occur hours or days after the passage of surface waves, and are marked by an increase in seismicity relative to background. Only one of the events, on September 18, 2009, occurred within the Socorro Magma Body area. The rest of these events occur spread throughout New Mexico. The widely spread distribution of possibly

  3. Study of Tectonic Tremor in Depth: Triggering Stress Observation and Model of the Triggering Mechanism

    NASA Astrophysics Data System (ADS)

    Wang, Tien-Huei

    including NVT occur on these sections have slower slip rates than that of the general earthquakes (Rubin, 2008; Ide, 2008). In Azna region, we use envelope and waveform cross-correlation to detect tremor. We investigate the stress required to trigger tremor and tremor spectrum using continuous broadband seismograms from 11 stations located near Anza, California. We examine 44 Mw≥7.4 teleseismic events between 2001 and 2011, in addition to one regional earthquake of smaller-magnitude, the 2009 Mw 6.5 Gulf of California earthquake, because it induced extremely high strain at Anza. The result suggests that not only the amplitude of the induced strain, but also the period of the incoming surface wave, may control triggering of tremor near Anza. In addition, we find that the transient-shear stress (17--35 kPa) required to trigger tremor along the SJF at Anza is distinctly higher than what has been reported for the well-studied SAF (Gulihem et al. 2010). We model slip initiation using the analytical solution of rate-and-state friction. We verify the correctness of this method by comparing the results with that from the dynamic model, implemented using the Multi-Dimensional Spectral Boundary Integral Code (MDSBI) written by Eric M. Dunham from Sanford University. We find that the analytical result is consistent with that of the dynamic model. We set up a patch model with which the source stress and frictional conditions best resemble the current estimates of the tremor source. The frictional regime of this patch is rate-weakening. The initial normal and shear stress, and friction parameters are suggested by previous observations of tectonic tremors both in this and other studies (Brown et al., 2005; Shelly et al., 2006; Miyazawa, 2008; Ben-Zion, 2012). Our dynamic loading first consists of simple harmonic stress change with fixed periods, simplifying the transient stress history to resemble teleseismic earthquakes. We tested the period and amplitude of such periodic loading. We

  4. Evaluation of digital soil mapping approaches with large sets of environmental covariates

    NASA Astrophysics Data System (ADS)

    Nussbaum, Madlene; Spiess, Kay; Baltensweiler, Andri; Grob, Urs; Keller, Armin; Greiner, Lucie; Schaepman, Michael E.; Papritz, Andreas

    2018-01-01

    The spatial assessment of soil functions requires maps of basic soil properties. Unfortunately, these are either missing for many regions or are not available at the desired spatial resolution or down to the required soil depth. The field-based generation of large soil datasets and conventional soil maps remains costly. Meanwhile, legacy soil data and comprehensive sets of spatial environmental data are available for many regions. Digital soil mapping (DSM) approaches relating soil data (responses) to environmental data (covariates) face the challenge of building statistical models from large sets of covariates originating, for example, from airborne imaging spectroscopy or multi-scale terrain analysis. We evaluated six approaches for DSM in three study regions in Switzerland (Berne, Greifensee, ZH forest) by mapping the effective soil depth available to plants (SD), pH, soil organic matter (SOM), effective cation exchange capacity (ECEC), clay, silt, gravel content and fine fraction bulk density for four soil depths (totalling 48 responses). Models were built from 300-500 environmental covariates by selecting linear models through (1) grouped lasso and (2) an ad hoc stepwise procedure for robust external-drift kriging (georob). For (3) geoadditive models we selected penalized smoothing spline terms by component-wise gradient boosting (geoGAM). We further used two tree-based methods: (4) boosted regression trees (BRTs) and (5) random forest (RF). Lastly, we computed (6) weighted model averages (MAs) from the predictions obtained from methods 1-5. Lasso, georob and geoGAM successfully selected strongly reduced sets of covariates (subsets of 3-6 % of all covariates). Differences in predictive performance, tested on independent validation data, were mostly small and did not reveal a single best method for 48 responses. Nevertheless, RF was often the best among methods 1-5 (28 of 48 responses), but was outcompeted by MA for 14 of these 28 responses. RF tended to over

  5. Combat veterans: impressions of an analytic observer in a non-analytic setting.

    PubMed

    Stein, Herbert H

    2007-01-01

    The hallmark presentation of combat trauma-nightmares, waking hallucinations, intrusive traumatic memories, and extreme affective reactions to environmental triggers-may best be conceptualized as part of an adaptive mechanism intended to protect the individual against a repetition of trauma. Combat veterans continuously must cope with the extreme affects that combat induced. Fear, rage, guilt, and grief predominate. Their mental and emotional life is complicated by a conscience split between war zone and civilian morality and by the special group dynamics of combat. Optimal clinical understanding of combat-related trauma, whether in a psychoanalytic or general mental health setting, requires an awareness of the interaction of the personal dynamics of each individual with the specific characteristics of their combat situation.

  6. Education in Environmental Chemistry: Setting the Agenda and Recommending Action. A Workshop Report Summary

    NASA Astrophysics Data System (ADS)

    Zoller, Uri

    2005-08-01

    Worldwide, the essence of the current reform in science education is a paradigm shift from algorithmic, lower-order cognitive skills (LOCS) teaching to higher-order cognitive skills (HOCS) learning. In the context of education in environmental chemistry (EEC), the ultimate goal is to educate students to be science technology environment society (STES)-literate, capable of evaluative thinking, decision making, problem solving and taking responsible action accordingly. Educators need to translate this goal into effective courses that can be implemented: this includes developing teaching strategies and assessment methodologies that are consonant with the goal of HOCS learning. An international workshop—"Environmental Chemistry Education in Europe: Setting the Agenda"—yielded two main recommendations for those undertaking educational reform in science education, particularly to promote meaningful EEC. The first recommendation concerns integration of environmental sciences into core chemistry courses as well as the development and implementation of HOCS-promoting teaching strategies and assessment methodologies in chemical education. The second emphasizes the development of students' HOCS for transfer, followed by performance assessment of HOCS. This requires changing the way environmental chemistry is typically taught, moving from a narrowly focused approach (applied analytical, ecotoxicological, or environmental engineering chemistry) to an interdisciplinary and multidisciplinary approach.

  7. FPGA-based Trigger System for the Fermilab SeaQuest Experimentz

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shiu, Shiuan-Hal; Wu, Jinyuan; McClellan, Randall Evan

    The SeaQuest experiment (Fermilab E906) detects pairs of energetic μ + and μ -produced in 120 GeV/c proton–nucleon interactions in a high rate environment. The trigger system we used consists of several arrays of scintillator hodoscopes and a set of field-programmable gate array (FPGA) based VMEbus modules. Signals from up to 96 channels of hodoscope are digitized by each FPGA with a 1-ns resolution using the time-to-digital convertor (TDC) firmware. The delay of the TDC output can be adjusted channel-by-channel in 1-ns step and then re-aligned with the beam RF clock. The hit pattern on the hodoscope planes is thenmore » examined against pre-determined trigger matrices to identify candidate muon tracks. Finally, information on the candidate tracks is sent to the 2nd-level FPGA-based track correlator to find candidate di-muon events. The design and implementation of the FPGA-based trigger system for SeaQuest experiment are presented.« less

  8. FPGA-based trigger system for the Fermilab SeaQuest experimentz

    NASA Astrophysics Data System (ADS)

    Shiu, Shiuan-Hal; Wu, Jinyuan; McClellan, Randall Evan; Chang, Ting-Hua; Chang, Wen-Chen; Chen, Yen-Chu; Gilman, Ron; Nakano, Kenichi; Peng, Jen-Chieh; Wang, Su-Yin

    2015-12-01

    The SeaQuest experiment (Fermilab E906) detects pairs of energetic μ+ and μ- produced in 120 GeV/c proton-nucleon interactions in a high rate environment. The trigger system consists of several arrays of scintillator hodoscopes and a set of field-programmable gate array (FPGA) based VMEbus modules. Signals from up to 96 channels of hodoscope are digitized by each FPGA with a 1-ns resolution using the time-to-digital convertor (TDC) firmware. The delay of the TDC output can be adjusted channel-by-channel in 1-ns step and then re-aligned with the beam RF clock. The hit pattern on the hodoscope planes is then examined against pre-determined trigger matrices to identify candidate muon tracks. Information on the candidate tracks is sent to the 2nd-level FPGA-based track correlator to find candidate di-muon events. The design and implementation of the FPGA-based trigger system for SeaQuest experiment are presented.

  9. FPGA-based Trigger System for the Fermilab SeaQuest Experimentz

    DOE PAGES

    Shiu, Shiuan-Hal; Wu, Jinyuan; McClellan, Randall Evan; ...

    2015-09-10

    The SeaQuest experiment (Fermilab E906) detects pairs of energetic μ + and μ -produced in 120 GeV/c proton–nucleon interactions in a high rate environment. The trigger system we used consists of several arrays of scintillator hodoscopes and a set of field-programmable gate array (FPGA) based VMEbus modules. Signals from up to 96 channels of hodoscope are digitized by each FPGA with a 1-ns resolution using the time-to-digital convertor (TDC) firmware. The delay of the TDC output can be adjusted channel-by-channel in 1-ns step and then re-aligned with the beam RF clock. The hit pattern on the hodoscope planes is thenmore » examined against pre-determined trigger matrices to identify candidate muon tracks. Finally, information on the candidate tracks is sent to the 2nd-level FPGA-based track correlator to find candidate di-muon events. The design and implementation of the FPGA-based trigger system for SeaQuest experiment are presented.« less

  10. Triggered emissions close to the proton gyrofrequency seen by Cluster

    NASA Astrophysics Data System (ADS)

    Grison, Benjamin; Pickett, Jolene; Omura, Yoshiharu; Santolik, Ondrej; Decreau, Pierrette; Masson, Arnaud; Engebretson, Mark; Cornilleau-Wehrlin, Nicole; Robert, Patrick; Dandouras, Iannis

    Electromagnetic ion cyclotron (EMIC) triggered emissions have been recently observed onboard the Cluster spacecraft close to the plasmapause in the equatorial region of the magnetosphere. These waves appear as "risers": electromagnetic structures that have a positive frequency drift with time, i.e., the EMIC analogue of rising frequency whistler mode triggered emissions and chorus waves. In our first results concerning the emission process based on a single event, these risers have the following properties: they propagate away from the direction of the magnetic equator, they have elliptical left-handed polarization corresponding to the transverse Alfven mode, and frequency drifts of about 30 mHz/s. These risers are not common in the Cluster data set. Nevertheless a few other events were found with similar properties. Another interesting preliminary result is the existence of risers with a polarization opposite that of the EMIC triggered emissions and which correspond to the fast magnetosonic mode.

  11. 40 CFR 355.12 - What quantities of extremely hazardous substances trigger emergency planning requirements?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 28 2011-07-01 2011-07-01 false What quantities of extremely hazardous substances trigger emergency planning requirements? 355.12 Section 355.12 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS...

  12. Unmasked adult-onset urea cycle disorders in the critical care setting.

    PubMed

    Summar, Marshall L; Barr, Frederick; Dawling, Sheila; Smith, Wendy; Lee, Brendan; Singh, Rani H; Rhead, William J; Sniderman King, Lisa; Christman, Brian W

    2005-10-01

    Most often, urea cycle disorders have been described as acute onset hyperammonemia in the newborn period; however, there is a growing awareness that urea cycle disorders can present at almost any age, frequently in the critical care setting. This article presents three cases of adult-onset hyperammonemia caused by inherited defects in nitrogen processing in the urea cycle, and reviews the diagnosis, management, and pathophysiology of adult-onset urea cycle disorders. Individuals who have milder molecular urea cycle defects can lead a relatively normal life until a severe environmental stress triggers a hyperammonemic crisis. Comorbid conditions such as physical trauma often delay the diagnosis of the urea cycle defect. Prompt recognition and treatment are essential in determining the outcome of these patients.

  13. The CMS trigger system

    NASA Astrophysics Data System (ADS)

    Khachatryan, V.; Sirunyan, A. M.; Tumasyan, A.; Adam, W.; Asilar, E.; Bergauer, T.; Brandstetter, J.; Brondolin, E.; Dragicevic, M.; Erö, J.; Flechl, M.; Friedl, M.; Frühwirth, R.; Ghete, V. M.; Hartl, C.; Hörmann, N.; Hrubec, J.; Jeitler, M.; Knünz, V.; König, A.; Krammer, M.; Krätschmer, I.; Liko, D.; Matsushita, T.; Mikulec, I.; Rabady, D.; Rahbaran, B.; Rohringer, H.; Schieck, J.; Schöfbeck, R.; Strauss, J.; Treberer-Treberspurg, W.; Waltenberger, W.; Wulz, C.-E.; Mossolov, V.; Shumeiko, N.; Suarez Gonzalez, J.; Alderweireldt, S.; Cornelis, T.; De Wolf, E. A.; Janssen, X.; Knutsson, A.; Lauwers, J.; Luyckx, S.; Van De Klundert, M.; Van Haevermaet, H.; Van Mechelen, P.; Van Remortel, N.; Van Spilbeeck, A.; Abu Zeid, S.; Blekman, F.; D'Hondt, J.; Daci, N.; De Bruyn, I.; Deroover, K.; Heracleous, N.; Keaveney, J.; Lowette, S.; Moreels, L.; Olbrechts, A.; Python, Q.; Strom, D.; Tavernier, S.; Van Doninck, W.; Van Mulders, P.; Van Onsem, G. P.; Van Parijs, I.; Barria, P.; Brun, H.; Caillol, C.; Clerbaux, B.; De Lentdecker, G.; Fasanella, G.; Favart, L.; Grebenyuk, A.; Karapostoli, G.; Lenzi, T.; Léonard, A.; Maerschalk, T.; Marinov, A.; Perniè, L.; Randle-conde, A.; Reis, T.; Seva, T.; Vander Velde, C.; Vanlaer, P.; Yonamine, R.; Zenoni, F.; Zhang, F.; Beernaert, K.; Benucci, L.; Cimmino, A.; Crucy, S.; Dobur, D.; Fagot, A.; Garcia, G.; Gul, M.; Mccartin, J.; Ocampo Rios, A. A.; Poyraz, D.; Ryckbosch, D.; Salva, S.; Sigamani, M.; Strobbe, N.; Tytgat, M.; Van Driessche, W.; Yazgan, E.; Zaganidis, N.; Basegmez, S.; Beluffi, C.; Bondu, O.; Brochet, S.; Bruno, G.; Caudron, A.; Ceard, L.; Da Silveira, G. G.; Delaere, C.; Favart, D.; Forthomme, L.; Giammanco, A.; Hollar, J.; Jafari, A.; Jez, P.; Komm, M.; Lemaitre, V.; Mertens, A.; Musich, M.; Nuttens, C.; Perrini, L.; Pin, A.; Piotrzkowski, K.; Popov, A.; Quertenmont, L.; Selvaggi, M.; Vidal Marono, M.; Beliy, N.; Hammad, G. H.; Aldá Júnior, W. L.; Alves, F. L.; Alves, G. A.; Brito, L.; Correa Martins Junior, M.; Hamer, M.; Hensel, C.; Mora Herrera, C.; Moraes, A.; Pol, M. E.; Rebello Teles, P.; Belchior Batista Das Chagas, E.; Carvalho, W.; Chinellato, J.; Custódio, A.; Da Costa, E. M.; Damiao, D. De Jesus; De Oliveira Martins, C.; Fonseca De Souza, S.; Huertas Guativa, L. M.; Malbouisson, H.; Matos Figueiredo, D.; Mundim, L.; Nogima, H.; Prado Da Silva, W. L.; Santoro, A.; Sznajder, A.; Tonelli Manganote, E. J.; Vilela Pereira, A.; Ahuja, S.; Bernardes, C. A.; De Souza Santos, A.; Dogra, S.; Fernandez Perez Tomei, T. R.; Gregores, E. M.; Mercadante, P. G.; Moon, C. S.; Novaes, S. F.; Padula, Sandra S.; Romero Abad, D.; Ruiz Vargas, J. C.; Aleksandrov, A.; Hadjiiska, R.; Iaydjiev, P.; Rodozov, M.; Stoykova, S.; Sultanov, G.; Vutova, M.; Dimitrov, A.; Glushkov, I.; Litov, L.; Pavlov, B.; Petkov, P.; Ahmad, M.; Bian, J. G.; Chen, G. M.; Chen, H. S.; Chen, M.; Cheng, T.; Du, R.; Jiang, C. H.; Plestina, R.; Romeo, F.; Shaheen, S. M.; Spiezia, A.; Tao, J.; Wang, C.; Wang, Z.; Zhang, H.; Asawatangtrakuldee, C.; Ban, Y.; Li, Q.; Liu, S.; Mao, Y.; Qian, S. J.; Wang, D.; Xu, Z.; Avila, C.; Cabrera, A.; Chaparro Sierra, L. F.; Florez, C.; Gomez, J. P.; Gomez Moreno, B.; Sanabria, J. C.; Godinovic, N.; Lelas, D.; Puljak, I.; Ribeiro Cipriano, P. M.; Antunovic, Z.; Kovac, M.; Brigljevic, V.; Kadija, K.; Luetic, J.; Micanovic, S.; Sudic, L.; Attikis, A.; Mavromanolakis, G.; Mousa, J.; Nicolaou, C.; Ptochos, F.; Razis, P. A.; Rykaczewski, H.; Bodlak, M.; Finger, M.; Finger, M., Jr.; Assran, Y.; El Sawy, M.; Elgammal, S.; Ellithi Kamel, A.; Mahmoud, M. A.; Calpas, B.; Kadastik, M.; Murumaa, M.; Raidal, M.; Tiko, A.; Veelken, C.; Eerola, P.; Pekkanen, J.; Voutilainen, M.; Härkönen, J.; Karimäki, V.; Kinnunen, R.; Lampén, T.; Lassila-Perini, K.; Lehti, S.; Lindén, T.; Luukka, P.; Mäenpää, T.; Peltola, T.; Tuominen, E.; Tuominiemi, J.; Tuovinen, E.; Wendland, L.; Talvitie, J.; Tuuva, T.; Besancon, M.; Couderc, F.; Dejardin, M.; Denegri, D.; Fabbro, B.; Faure, J. L.; Favaro, C.; Ferri, F.; Ganjour, S.; Givernaud, A.; Gras, P.; Hamel de Monchenault, G.; Jarry, P.; Locci, E.; Machet, M.; Malcles, J.; Rander, J.; Rosowsky, A.; Titov, M.; Zghiche, A.; Antropov, I.; Baffioni, S.; Beaudette, F.; Busson, P.; Cadamuro, L.; Chapon, E.; Charlot, C.; Dahms, T.; Davignon, O.; Filipovic, N.; Florent, A.; Granier de Cassagnac, R.; Lisniak, S.; Mastrolorenzo, L.; Miné, P.; Naranjo, I. N.; Nguyen, M.; Ochando, C.; Ortona, G.; Paganini, P.; Pigard, P.; Regnard, S.; Salerno, R.; Sauvan, J. B.; Sirois, Y.; Strebler, T.; Yilmaz, Y.; Zabi, A.; Agram, J.-L.; Andrea, J.; Aubin, A.; Bloch, D.; Brom, J.-M.; Buttignol, M.; Chabert, E. C.; Chanon, N.; Collard, C.; Conte, E.; Coubez, X.; Fontaine, J.-C.; Gelé, D.; Goerlach, U.; Goetzmann, C.; Le Bihan, A.-C.; Merlin, J. A.; Skovpen, K.; Van Hove, P.; Gadrat, S.; Beauceron, S.; Bernet, C.; Boudoul, G.; Bouvier, E.; Carrillo Montoya, C. A.; Chierici, R.; Contardo, D.; Courbon, B.; Depasse, P.; El Mamouni, H.; Fan, J.; Fay, J.; Gascon, S.; Gouzevitch, M.; Ille, B.; Lagarde, F.; Laktineh, I. B.; Lethuillier, M.; Mirabito, L.; Pequegnot, A. L.; Perries, S.; Ruiz Alvarez, J. D.; Sabes, D.; Sgandurra, L.; Sordini, V.; Vander Donckt, M.; Verdier, P.; Viret, S.; Toriashvili, T.; Tsamalaidze, Z.; Autermann, C.; Beranek, S.; Edelhoff, M.; Feld, L.; Heister, A.; Kiesel, M. K.; Klein, K.; Lipinski, M.; Ostapchuk, A.; Preuten, M.; Raupach, F.; Schael, S.; Schulte, J. F.; Verlage, T.; Weber, H.; Wittmer, B.; Zhukov, V.; Ata, M.; Brodski, M.; Dietz-Laursonn, E.; Duchardt, D.; Endres, M.; Erdmann, M.; Erdweg, S.; Esch, T.; Fischer, R.; Güth, A.; Hebbeker, T.; Heidemann, C.; Hoepfner, K.; Klingebiel, D.; Knutzen, S.; Kreuzer, P.; Merschmeyer, M.; Meyer, A.; Millet, P.; Olschewski, M.; Padeken, K.; Papacz, P.; Pook, T.; Radziej, M.; Reithler, H.; Rieger, M.; Scheuch, F.; Sonnenschein, L.; Teyssier, D.; Thüer, S.; Cherepanov, V.; Erdogan, Y.; Flügge, G.; Geenen, H.; Geisler, M.; Hoehle, F.; Kargoll, B.; Kress, T.; Kuessel, Y.; Künsken, A.; Lingemann, J.; Nehrkorn, A.; Nowack, A.; Nugent, I. M.; Pistone, C.; Pooth, O.; Stahl, A.; Aldaya Martin, M.; Asin, I.; Bartosik, N.; Behnke, O.; Behrens, U.; Bell, A. J.; Borras, K.; Burgmeier, A.; Campbell, A.; Choudhury, S.; Costanza, F.; Diez Pardos, C.; Dolinska, G.; Dooling, S.; Dorland, T.; Eckerlin, G.; Eckstein, D.; Eichhorn, T.; Flucke, G.; Gallo, E.; Garay Garcia, J.; Geiser, A.; Gizhko, A.; Gunnellini, P.; Hauk, J.; Hempel, M.; Jung, H.; Kalogeropoulos, A.; Karacheban, O.; Kasemann, M.; Katsas, P.; Kieseler, J.; Kleinwort, C.; Korol, I.; Lange, W.; Leonard, J.; Lipka, K.; Lobanov, A.; Lohmann, W.; Mankel, R.; Marfin, I.; Melzer-Pellmann, I.-A.; Meyer, A. B.; Mittag, G.; Mnich, J.; Mussgiller, A.; Naumann-Emme, S.; Nayak, A.; Ntomari, E.; Perrey, H.; Pitzl, D.; Placakyte, R.; Raspereza, A.; Roland, B.; Sahin, M. Ö.; Saxena, P.; Schoerner-Sadenius, T.; Schröder, M.; Seitz, C.; Spannagel, S.; Trippkewitz, K. D.; Walsh, R.; Wissing, C.; Blobel, V.; Centis Vignali, M.; Draeger, A. R.; Erfle, J.; Garutti, E.; Goebel, K.; Gonzalez, D.; Görner, M.; Haller, J.; Hoffmann, M.; Höing, R. S.; Junkes, A.; Klanner, R.; Kogler, R.; Kovalchuk, N.; Lapsien, T.; Lenz, T.; Marchesini, I.; Marconi, D.; Meyer, M.; Nowatschin, D.; Ott, J.; Pantaleo, F.; Peiffer, T.; Perieanu, A.; Pietsch, N.; Poehlsen, J.; Rathjens, D.; Sander, C.; Scharf, C.; Schettler, H.; Schleper, P.; Schlieckau, E.; Schmidt, A.; Schwandt, J.; Sola, V.; Stadie, H.; Steinbrück, G.; Tholen, H.; Troendle, D.; Usai, E.; Vanelderen, L.; Vanhoefer, A.; Vormwald, B.; Akbiyik, M.; Barth, C.; Baus, C.; Berger, J.; Böser, C.; Butz, E.; Chwalek, T.; Colombo, F.; De Boer, W.; Descroix, A.; Dierlamm, A.; Fink, S.; Frensch, F.; Friese, R.; Giffels, M.; Gilbert, A.; Haitz, D.; Hartmann, F.; Heindl, S. M.; Husemann, U.; Katkov, I.; Kornmayer, A.; Lobelle Pardo, P.; Maier, B.; Mildner, H.; Mozer, M. U.; Müller, T.; Müller, Th.; Plagge, M.; Quast, G.; Rabbertz, K.; Röcker, S.; Roscher, F.; Sieber, G.; Simonis, H. J.; Stober, F. M.; Ulrich, R.; Wagner-Kuhr, J.; Wayand, S.; Weber, M.; Weiler, T.; Wöhrmann, C.; Wolf, R.; Anagnostou, G.; Daskalakis, G.; Geralis, T.; Giakoumopoulou, V. A.; Kyriakis, A.; Loukas, D.; Psallidas, A.; Topsis-Giotis, I.; Agapitos, A.; Kesisoglou, S.; Panagiotou, A.; Saoulidou, N.; Tziaferi, E.; Evangelou, I.; Flouris, G.; Foudas, C.; Kokkas, P.; Loukas, N.; Manthos, N.; Papadopoulos, I.; Paradas, E.; Strologas, J.; Bencze, G.; Hajdu, C.; Hazi, A.; Hidas, P.; Horvath, D.; Sikler, F.; Veszpremi, V.; Vesztergombi, G.; Zsigmond, A. J.; Beni, N.; Czellar, S.; Karancsi, J.; Molnar, J.; Szillasi, Z.; Bartók, M.; Makovec, A.; Raics, P.; Trocsanyi, Z. L.; Ujvari, B.; Mal, P.; Mandal, K.; Sahoo, D. K.; Sahoo, N.; Swain, S. K.; Bansal, S.; Beri, S. B.; Bhatnagar, V.; Chawla, R.; Gupta, R.; Bhawandeep, U.; Kalsi, A. K.; Kaur, A.; Kaur, M.; Kumar, R.; Mehta, A.; Mittal, M.; Singh, J. B.; Walia, G.; Kumar, Ashok; Bhardwaj, A.; Choudhary, B. C.; Garg, R. B.; Kumar, A.; Malhotra, S.; Naimuddin, M.; Nishu, N.; Ranjan, K.; Sharma, R.; Sharma, V.; Bhattacharya, S.; Chatterjee, K.; Dey, S.; Dutta, S.; Jain, Sa.; Majumdar, N.; Modak, A.; Mondal, K.; Mukherjee, S.; Mukhopadhyay, S.; Roy, A.; Roy, D.; Chowdhury, S. Roy; Sarkar, S.; Sharan, M.; Abdulsalam, A.; Chudasama, R.; Dutta, D.; Jha, V.; Kumar, V.; Mohanty, A. K.; Pant, L. M.; Shukla, P.; Topkar, A.; Aziz, T.; Banerjee, S.; Bhowmik, S.; Chatterjee, R. M.; Dewanjee, R. K.; Dugad, S.; Ganguly, S.; Ghosh, S.; Guchait, M.; Gurtu, A.; Kole, G.; Kumar, S.; Mahakud, B.; Maity, M.; Majumder, G.; Mazumdar, K.; Mitra, S.; Mohanty, G. B.; Parida, B.; Sarkar, T.; Sur, N.; Sutar, B.; Wickramage, N.; Chauhan, S.; Dube, S.; Kothekar, K.; Sharma, S.; Bakhshiansohi, H.; Behnamian, H.; Etesami, S. M.; Fahim, A.; Goldouzian, R.; Khakzad, M.; Najafabadi, M. Mohammadi; Naseri, M.; Paktinat Mehdiabadi, S.; Rezaei Hosseinabadi, F.; Safarzadeh, B.; Zeinali, M.; Felcini, M.; Grunewald, M.; Abbrescia, M.; Calabria, C.; Caputo, C.; Colaleo, A.; Creanza, D.; Cristella, L.; De Filippis, N.; De Palma, M.; Fiore, L.; Iaselli, G.; Maggi, G.; Maggi, M.; Miniello, G.; My, S.; Nuzzo, S.; Pompili, A.; Pugliese, G.; Radogna, R.; Ranieri, A.; Selvaggi, G.; Silvestris, L.; Venditti, R.; Verwilligen, P.; Abbiendi, G.; Battilana, C.; Benvenuti, A. C.; Bonacorsi, D.; Braibant-Giacomelli, S.; Brigliadori, L.; Campanini, R.; Capiluppi, P.; Castro, A.; Cavallo, F. R.; Chhibra, S. S.; Codispoti, G.; Cuffiani, M.; Dallavalle, G. M.; Fabbri, F.; Fanfani, A.; Fasanella, D.; Giacomelli, P.; Grandi, C.; Guiducci, L.; Marcellini, S.; Masetti, G.; Montanari, A.; Navarria, F. L.; Perrotta, A.; Rossi, A. M.; Rovelli, T.; Siroli, G. P.; Tosi, N.; Travaglini, R.; Cappello, G.; Chiorboli, M.; Costa, S.; Di Mattia, A.; Giordano, F.; Potenza, R.; Tricomi, A.; Tuve, C.; Barbagli, G.; Ciulli, V.; Civinini, C.; D'Alessandro, R.; Focardi, E.; Gonzi, S.; Gori, V.; Lenzi, P.; Meschini, M.; Paoletti, S.; Sguazzoni, G.; Tropiano, A.; Viliani, L.; Benussi, L.; Bianco, S.; Fabbri, F.; Piccolo, D.; Primavera, F.; Calvelli, V.; Ferro, F.; Lo Vetere, M.; Monge, M. R.; Robutti, E.; Tosi, S.; Brianza, L.; Dinardo, M. E.; Fiorendi, S.; Gennai, S.; Gerosa, R.; Ghezzi, A.; Govoni, P.; Malvezzi, S.; Manzoni, R. A.; Marzocchi, B.; Menasce, D.; Moroni, L.; Paganoni, M.; Pedrini, D.; Ragazzi, S.; Redaelli, N.; Tabarelli de Fatis, T.; Buontempo, S.; Cavallo, N.; Di Guida, S.; Esposito, M.; Fabozzi, F.; Iorio, A. O. M.; Lanza, G.; Lista, L.; Meola, S.; Merola, M.; Paolucci, P.; Sciacca, C.; Thyssen, F.; Bacchetta, N.; Bellato, M.; Benato, L.; Bisello, D.; Boletti, A.; Carlin, R.; Checchia, P.; Dall'Osso, M.; Dosselli, U.; Gasparini, F.; Gasparini, U.; Gozzelino, A.; Lacaprara, S.; Margoni, M.; Meneguzzo, A. T.; Montecassiano, F.; Passaseo, M.; Pazzini, J.; Pegoraro, M.; Pozzobon, N.; Simonetto, F.; Torassa, E.; Tosi, M.; Vanini, S.; Ventura, S.; Zanetti, M.; Zotto, P.; Zucchetta, A.; Zumerle, G.; Braghieri, A.; Magnani, A.; Montagna, P.; Ratti, S. P.; Re, V.; Riccardi, C.; Salvini, P.; Vai, I.; Vitulo, P.; Alunni Solestizi, L.; Biasini, M.; Bilei, G. M.; Ciangottini, D.; Fanò, L.; Lariccia, P.; Mantovani, G.; Menichelli, M.; Saha, A.; Santocchia, A.; Androsov, K.; Azzurri, P.; Bagliesi, G.; Bernardini, J.; Boccali, T.; Castaldi, R.; Ciocci, M. A.; Dell'Orso, R.; Donato, S.; Fedi, G.; Foà, L.; Giassi, A.; Grippo, M. T.; Ligabue, F.; Lomtadze, T.; Martini, L.; Messineo, A.; Palla, F.; Rizzi, A.; Savoy-Navarro, A.; Serban, A. T.; Spagnolo, P.; Tenchini, R.; Tonelli, G.; Venturi, A.; Verdini, P. G.; Barone, L.; Cavallari, F.; D'imperio, G.; Del Re, D.; Diemoz, M.; Gelli, S.; Jorda, C.; Longo, E.; Margaroli, F.; Meridiani, P.; Organtini, G.; Paramatti, R.; Preiato, F.; Rahatlou, S.; Rovelli, C.; Santanastasio, F.; Traczyk, P.; Amapane, N.; Arcidiacono, R.; Argiro, S.; Arneodo, M.; Bellan, R.; Biino, C.; Cartiglia, N.; Costa, M.; Covarelli, R.; Degano, A.; Demaria, N.; Finco, L.; Kiani, B.; Mariotti, C.; Maselli, S.; Migliore, E.; Monaco, V.; Monteil, E.; Obertino, M. M.; Pacher, L.; Pastrone, N.; Pelliccioni, M.; Pinna Angioni, G. L.; Ravera, F.; Romero, A.; Ruspa, M.; Sacchi, R.; Solano, A.; Staiano, A.; Tamponi, U.; Belforte, S.; Candelise, V.; Casarsa, M.; Cossutti, F.; Della Ricca, G.; Gobbo, B.; La Licata, C.; Marone, M.; Schizzi, A.; Zanetti, A.; Kropivnitskaya, A.; Nam, S. K.; Kim, D. H.; Kim, G. N.; Kim, M. S.; Kong, D. J.; Lee, S.; Oh, Y. D.; Sakharov, A.; Son, D. C.; Brochero Cifuentes, J. A.; Kim, H.; Kim, T. J.; Song, S.; Choi, S.; Go, Y.; Gyun, D.; Hong, B.; Jo, M.; Kim, H.; Kim, Y.; Lee, B.; Lee, K.; Lee, K. S.; Lee, S.; Park, S. K.; Roh, Y.; Yoo, H. D.; Choi, M.; Kim, H.; Kim, J. H.; Lee, J. S. H.; Park, I. C.; Ryu, G.; Ryu, M. S.; Choi, Y.; Goh, J.; Kim, D.; Kwon, E.; Lee, J.; Yu, I.; Dudenas, V.; Juodagalvis, A.; Vaitkus, J.; Ahmed, I.; Ibrahim, Z. A.; Komaragiri, J. R.; Ali, M. A. B. Md; Mohamad Idris, F.; Abdullah, W. A. T. Wan; Yusli, M. N.; Casimiro Linares, E.; Castilla-Valdez, H.; De La Cruz-Burelo, E.; Heredia-De La Cruz, I.; Hernandez-Almada, A.; Lopez-Fernandez, R.; Sanchez-Hernandez, A.; Carrillo Moreno, S.; Vazquez Valencia, F.; Pedraza, I.; Salazar Ibarguen, H. A.; Morelos Pineda, A.; Krofcheck, D.; Butler, P. H.; Ahmad, A.; Ahmad, M.; Hassan, Q.; Hoorani, H. R.; Khan, W. A.; Khurshid, T.; Shoaib, M.; Bialkowska, H.; Bluj, M.; Boimska, B.; Frueboes, T.; Górski, M.; Kazana, M.; Nawrocki, K.; Romanowska-Rybinska, K.; Szleper, M.; Zalewski, P.; Brona, G.; Bunkowski, K.; Byszuk, A.; Doroba, K.; Kalinowski, A.; Kierzkowski, K.; Konecki, M.; Krolikowski, J.; Misiura, M.; Oklinski, W.; Olszewski, M.; Pozniak, K.; Walczak, M.; Zabolotny, W.; Bargassa, P.; Silva, C. Beirão Da Cruz E.; Di Francesco, A.; Faccioli, P.; Ferreira Parracho, P. G.; Gallinaro, M.; Leonardo, N.; Lloret Iglesias, L.; Nguyen, F.; Rodrigues Antunes, J.; Seixas, J.; Toldaiev, O.; Vadruccio, D.; Varela, J.; Vischia, P.; Afanasiev, S.; Bunin, P.; Gavrilenko, M.; Golutvin, I.; Gorbunov, I.; Kamenev, A.; Karjavin, V.; Konoplyanikov, V.; Lanev, A.; Malakhov, A.; Matveev, V.; Moisenz, P.; Palichik, V.; Perelygin, V.; Shmatov, S.; Shulha, S.; Skatchkov, N.; Smirnov, V.; Zarubin, A.; Golovtsov, V.; Ivanov, Y.; Kim, V.; Kuznetsova, E.; Levchenko, P.; Murzin, V.; Oreshkin, V.; Smirnov, I.; Sulimov, V.; Uvarov, L.; Vavilov, S.; Vorobyev, A.; Andreev, Yu.; Dermenev, A.; Gninenko, S.; Golubev, N.; Karneyeu, A.; Kirsanov, M.; Krasnikov, N.; Pashenkov, A.; Tlisov, D.; Toropin, A.; Epshteyn, V.; Gavrilov, V.; Lychkovskaya, N.; Popov, V.; Pozdnyakov, I.; Safronov, G.; Spiridonov, A.; Vlasov, E.; Zhokin, A.; Bylinkin, A.; Andreev, V.; Azarkin, M.; Dremin, I.; Kirakosyan, M.; Leonidov, A.; Mesyats, G.; Rusakov, S. V.; Baskakov, A.; Belyaev, A.; Boos, E.; Dubinin, M.; Dudko, L.; Ershov, A.; Gribushin, A.; Kaminskiy, A.; Klyukhin, V.; Kodolova, O.; Lokhtin, I.; Myagkov, I.; Obraztsov, S.; Petrushanko, S.; Savrin, V.; Azhgirey, I.; Bayshev, I.; Bitioukov, S.; Kachanov, V.; Kalinin, A.; Konstantinov, D.; Krychkine, V.; Petrov, V.; Ryutin, R.; Sobol, A.; Tourtchanovitch, L.; Troshin, S.; Tyurin, N.; Uzunian, A.; Volkov, A.; Adzic, P.; Milosevic, J.; Rekovic, V.; Alcaraz Maestre, J.; Calvo, E.; Cerrada, M.; Chamizo Llatas, M.; Colino, N.; De La Cruz, B.; Delgado Peris, A.; Domínguez Vázquez, D.; Escalante Del Valle, A.; Fernandez Bedoya, C.; Fernández Ramos, J. P.; Flix, J.; Fouz, M. C.; Garcia-Abia, P.; Gonzalez Lopez, O.; Goy Lopez, S.; Hernandez, J. M.; Josa, M. I.; Navarro De Martino, E.; Pérez-Calero Yzquierdo, A.; Puerta Pelayo, J.; Quintario Olmeda, A.; Redondo, I.; Romero, L.; Santaolalla, J.; Soares, M. S.; Albajar, C.; de Trocóniz, J. F.; Missiroli, M.; Moran, D.; Cuevas, J.; Fernandez Menendez, J.; Folgueras, S.; Gonzalez Caballero, I.; Palencia Cortezon, E.; Vizan Garcia, J. M.; Cabrillo, I. J.; Calderon, A.; Castiñeiras De Saa, J. R.; De Castro Manzano, P.; Duarte Campderros, J.; Fernandez, M.; Garcia-Ferrero, J.; Gomez, G.; Lopez Virto, A.; Marco, J.; Marco, R.; Martinez Rivero, C.; Matorras, F.; Munoz Sanchez, F. J.; Piedra Gomez, J.; Rodrigo, T.; Rodríguez-Marrero, A. Y.; Ruiz-Jimeno, A.; Scodellaro, L.; Trevisani, N.; Vila, I.; Vilar Cortabitarte, R.; Abbaneo, D.; Auffray, E.; Auzinger, G.; Bachtis, M.; Baillon, P.; Ball, A. H.; Barney, D.; Benaglia, A.; Bendavid, J.; Benhabib, L.; Benitez, J. F.; Berruti, G. M.; Bloch, P.; Bocci, A.; Bonato, A.; Botta, C.; Breuker, H.; Camporesi, T.; Castello, R.; Cerminara, G.; D'Alfonso, M.; d'Enterria, D.; Dabrowski, A.; Daponte, V.; David, A.; De Gruttola, M.; De Guio, F.; De Roeck, A.; De Visscher, S.; Di Marco, E.; Dobson, M.; Dordevic, M.; Dorney, B.; du Pree, T.; Dünser, M.; Dupont, N.; Elliott-Peisert, A.; Franzoni, G.; Funk, W.; Gigi, D.; Gill, K.; Giordano, D.; Girone, M.; Glege, F.; Guida, R.; Gundacker, S.; Guthoff, M.; Hammer, J.; Harris, P.; Hegeman, J.; Innocente, V.; Janot, P.; Kirschenmann, H.; Kortelainen, M. J.; Kousouris, K.; Krajczar, K.; Lecoq, P.; Lourenço, C.; Lucchini, M. T.; Magini, N.; Malgeri, L.; Mannelli, M.; Martelli, A.; Masetti, L.; Meijers, F.; Mersi, S.; Meschi, E.; Moortgat, F.; Morovic, S.; Mulders, M.; Nemallapudi, M. V.; Neugebauer, H.; Orfanelli, S.; Orsini, L.; Pape, L.; Perez, E.; Peruzzi, M.; Petrilli, A.; Petrucciani, G.; Pfeiffer, A.; Piparo, D.; Racz, A.; Rolandi, G.; Rovere, M.; Ruan, M.; Sakulin, H.; Schäfer, C.; Schwick, C.; Seidel, M.; Sharma, A.; Silva, P.; Simon, M.; Sphicas, P.; Steggemann, J.; Stieger, B.; Stoye, M.; Takahashi, Y.; Treille, D.; Triossi, A.; Tsirou, A.; Veres, G. I.; Wardle, N.; Wöhri, H. K.; Zagozdzinska, A.; Zeuner, W. D.; Bertl, W.; Deiters, K.; Erdmann, W.; Horisberger, R.; Ingram, Q.; Kaestli, H. C.; Kotlinski, D.; Langenegger, U.; Renker, D.; Rohe, T.; Bachmair, F.; Bäni, L.; Bianchini, L.; Casal, B.; Dissertori, G.; Dittmar, M.; Donegà, M.; Eller, P.; Grab, C.; Heidegger, C.; Hits, D.; Hoss, J.; Kasieczka, G.; Lustermann, W.; Mangano, B.; Marionneau, M.; Martinez Ruiz del Arbol, P.; Masciovecchio, M.; Meister, D.; Micheli, F.; Musella, P.; Nessi-Tedaldi, F.; Pandolfi, F.; Pata, J.; Pauss, F.; Perrozzi, L.; Quittnat, M.; Rossini, M.; Starodumov, A.; Takahashi, M.; Tavolaro, V. R.; Theofilatos, K.; Wallny, R.; Aarrestad, T. K.; Amsler, C.; Caminada, L.; Canelli, M. F.; Chiochia, V.; De Cosa, A.; Galloni, C.; Hinzmann, A.; Hreus, T.; Kilminster, B.; Lange, C.; Ngadiuba, J.; Pinna, D.; Robmann, P.; Ronga, F. J.; Salerno, D.; Yang, Y.; Cardaci, M.; Chen, K. H.; Doan, T. H.; Jain, Sh.; Khurana, R.; Konyushikhin, M.; Kuo, C. M.; Lin, W.; Lu, Y. J.; Yu, S. S.; Kumar, Arun; Bartek, R.; Chang, P.; Chang, Y. H.; Chang, Y. W.; Chao, Y.; Chen, K. F.; Chen, P. H.; Dietz, C.; Fiori, F.; Grundler, U.; Hou, W.-S.; Hsiung, Y.; Liu, Y. F.; Lu, R.-S.; Miñano Moya, M.; Petrakou, E.; Tsai, J. f.; Tzeng, Y. M.; Asavapibhop, B.; Kovitanggoon, K.; Singh, G.; Srimanobhas, N.; Suwonjandee, N.; Adiguzel, A.; Bakirci, M. N.; Demiroglu, Z. S.; Dozen, C.; Eskut, E.; Girgis, S.; Gokbulut, G.; Guler, Y.; Gurpinar, E.; Hos, I.; Kangal, E. E.; Onengut, G.; Ozdemir, K.; Polatoz, A.; Sunar Cerci, D.; Tali, B.; Topakli, H.; Vergili, M.; Zorbilmez, C.; Akin, I. V.; Bilin, B.; Bilmis, S.; Isildak, B.; Karapinar, G.; Yalvac, M.; Zeyrek, M.; Gülmez, E.; Kaya, M.; Kaya, O.; Yetkin, E. A.; Yetkin, T.; Cakir, A.; Cankocak, K.; Sen, S.; Vardarlı, F. I.; Grynyov, B.; Levchuk, L.; Sorokin, P.; Aggleton, R.; Ball, F.; Beck, L.; Brooke, J. J.; Clement, E.; Cussans, D.; Flacher, H.; Goldstein, J.; Grimes, M.; Heath, G. P.; Heath, H. F.; Jacob, J.; Kreczko, L.; Lucas, C.; Meng, Z.; Newbold, D. M.; Paramesvaran, S.; Poll, A.; Sakuma, T.; Seif El Nasr-storey, S.; Senkin, S.; Smith, D.; Smith, V. J.; Bell, K. W.; Belyaev, A.; Brew, C.; Brown, R. M.; Calligaris, L.; Cieri, D.; Cockerill, D. J. A.; Coughlan, J. A.; Harder, K.; Harper, S.; Olaiya, E.; Petyt, D.; Shepherd-Themistocleous, C. H.; Thea, A.; Tomalin, I. R.; Williams, T.; Womersley, W. J.; Worm, S. D.; Baber, M.; Bainbridge, R.; Buchmuller, O.; Bundock, A.; Burton, D.; Casasso, S.; Citron, M.; Colling, D.; Corpe, L.; Cripps, N.; Dauncey, P.; Davies, G.; De Wit, A.; Della Negra, M.; Dunne, P.; Elwood, A.; Ferguson, W.; Fulcher, J.; Futyan, D.; Hall, G.; Iles, G.; Kenzie, M.; Lane, R.; Lucas, R.; Lyons, L.; Magnan, A.-M.; Malik, S.; Nash, J.; Nikitenko, A.; Pela, J.; Pesaresi, M.; Petridis, K.; Raymond, D. M.; Richards, A.; Rose, A.; Seez, C.; Tapper, A.; Uchida, K.; Vazquez Acosta, M.; Virdee, T.; Zenz, S. C.; Cole, J. E.; Hobson, P. R.; Khan, A.; Kyberd, P.; Leggat, D.; Leslie, D.; Reid, I. D.; Symonds, P.; Teodorescu, L.; Turner, M.; Borzou, A.; Call, K.; Dittmann, J.; Hatakeyama, K.; Liu, H.; Pastika, N.; Charaf, O.; Cooper, S. I.; Henderson, C.; Rumerio, P.; Arcaro, D.; Avetisyan, A.; Bose, T.; Fantasia, C.; Gastler, D.; Lawson, P.; Rankin, D.; Richardson, C.; Rohlf, J.; St. John, J.; Sulak, L.; Zou, D.; Alimena, J.; Berry, E.; Bhattacharya, S.; Cutts, D.; Dhingra, N.; Ferapontov, A.; Garabedian, A.; Hakala, J.; Heintz, U.; Laird, E.; Landsberg, G.; Mao, Z.; Narain, M.; Piperov, S.; Sagir, S.; Syarif, R.; Breedon, R.; Breto, G.; Calderon De La Barca Sanchez, M.; Chauhan, S.; Chertok, M.; Conway, J.; Conway, R.; Cox, P. T.; Erbacher, R.; Gardner, M.; Ko, W.; Lander, R.; Mulhearn, M.; Pellett, D.; Pilot, J.; Ricci-Tam, F.; Shalhout, S.; Smith, J.; Squires, M.; Stolp, D.; Tripathi, M.; Wilbur, S.; Yohay, R.; Cousins, R.; Everaerts, P.; Farrell, C.; Hauser, J.; Ignatenko, M.; Saltzberg, D.; Takasugi, E.; Valuev, V.; Weber, M.; Burt, K.; Clare, R.; Ellison, J.; Gary, J. W.; Hanson, G.; Heilman, J.; Ivova PANEVA, M.; Jandir, P.; Kennedy, E.; Lacroix, F.; Long, O. R.; Luthra, A.; Malberti, M.; Olmedo Negrete, M.; Shrinivas, A.; Wei, H.; Wimpenny, S.; Yates, B. R.; Branson, J. G.; Cerati, G. B.; Cittolin, S.; D'Agnolo, R. T.; Derdzinski, M.; Holzner, A.; Kelley, R.; Klein, D.; Letts, J.; Macneill, I.; Olivito, D.; Padhi, S.; Pieri, M.; Sani, M.; Sharma, V.; Simon, S.; Tadel, M.; Vartak, A.; Wasserbaech, S.; Welke, C.; Würthwein, F.; Yagil, A.; Zevi Della Porta, G.; Bradmiller-Feld, J.; Campagnari, C.; Dishaw, A.; Dutta, V.; Flowers, K.; Sevilla, M. Franco; Geffert, P.; George, C.; Golf, F.; Gouskos, L.; Gran, J.; Incandela, J.; Mccoll, N.; Mullin, S. D.; Richman, J.; Stuart, D.; Suarez, I.; West, C.; Yoo, J.; Anderson, D.; Apresyan, A.; Bornheim, A.; Bunn, J.; Chen, Y.; Duarte, J.; Mott, A.; Newman, H. B.; Pena, C.; Pierini, M.; Spiropulu, M.; Vlimant, J. R.; Xie, S.; Zhu, R. Y.; Andrews, M. B.; Azzolini, V.; Calamba, A.; Carlson, B.; Ferguson, T.; Paulini, M.; Russ, J.; Sun, M.; Vogel, H.; Vorobiev, I.; Cumalat, J. P.; Ford, W. T.; Gaz, A.; Jensen, F.; Johnson, A.; Krohn, M.; Mulholland, T.; Nauenberg, U.; Stenson, K.; Wagner, S. R.; Alexander, J.; Chatterjee, A.; Chaves, J.; Chu, J.; Dittmer, S.; Eggert, N.; Mirman, N.; Kaufman, G. Nicolas; Patterson, J. R.; Rinkevicius, A.; Ryd, A.; Skinnari, L.; Soffi, L.; Sun, W.; Tan, S. M.; Teo, W. D.; Thom, J.; Thompson, J.; Tucker, J.; Weng, Y.; Wittich, P.; Abdullin, S.; Albrow, M.; Anderson, J.; Apollinari, G.; Banerjee, S.; Bauerdick, L. A. T.; Beretvas, A.; Berryhill, J.; Bhat, P. C.; Bolla, G.; Burkett, K.; Butler, J. N.; Cheung, H. W. K.; Chlebana, F.; Cihangir, S.; Elvira, V. D.; Fisk, I.; Freeman, J.; Gottschalk, E.; Gray, L.; Green, D.; Grünendahl, S.; Gutsche, O.; Hanlon, J.; Hare, D.; Harris, R. M.; Hasegawa, S.; Hirschauer, J.; Hu, Z.; Jayatilaka, B.; Jindariani, S.; Johnson, M.; Joshi, U.; Jung, A. W.; Klima, B.; Kreis, B.; Kwan, S.; Lammel, S.; Linacre, J.; Lincoln, D.; Lipton, R.; Liu, T.; Lopes De Sá, R.; Lykken, J.; Maeshima, K.; Marraffino, J. M.; Martinez Outschoorn, V. I.; Maruyama, S.; Mason, D.; McBride, P.; Merkel, P.; Mishra, K.; Mrenna, S.; Nahn, S.; Newman-Holmes, C.; O'Dell, V.; Pedro, K.; Prokofyev, O.; Rakness, G.; Sexton-Kennedy, E.; Soha, A.; Spalding, W. J.; Spiegel, L.; Taylor, L.; Tkaczyk, S.; Tran, N. V.; Uplegger, L.; Vaandering, E. W.; Vernieri, C.; Verzocchi, M.; Vidal, R.; Weber, H. A.; Whitbeck, A.; Yang, F.; Acosta, D.; Avery, P.; Bortignon, P.; Bourilkov, D.; Carnes, A.; Carver, M.; Curry, D.; Das, S.; Di Giovanni, G. P.; Field, R. D.; Furic, I. K.; Gleyzer, S. V.; Hugon, J.; Konigsberg, J.; Korytov, A.; Low, J. F.; Ma, P.; Matchev, K.; Mei, H.; Milenovic, P.; Mitselmakher, G.; Rank, D.; Rossin, R.; Shchutska, L.; Snowball, M.; Sperka, D.; Terentyev, N.; Thomas, L.; Wang, J.; Wang, S.; Yelton, J.; Hewamanage, S.; Linn, S.; Markowitz, P.; Martinez, G.; Rodriguez, J. L.; Ackert, A.; Adams, J. R.; Adams, T.; Askew, A.; Bochenek, J.; Diamond, B.; Haas, J.; Hagopian, S.; Hagopian, V.; Johnson, K. F.; Khatiwada, A.; Prosper, H.; Weinberg, M.; Baarmand, M. M.; Bhopatkar, V.; Colafranceschi, S.; Hohlmann, M.; Kalakhety, H.; Noonan, D.; Roy, T.; Yumiceva, F.; Adams, M. R.; Apanasevich, L.; Berry, D.; Betts, R. R.; Bucinskaite, I.; Cavanaugh, R.; Evdokimov, O.; Gauthier, L.; Gerber, C. E.; Hofman, D. J.; Kurt, P.; O'Brien, C.; Sandoval Gonzalez, I. D.; Silkworth, C.; Turner, P.; Varelas, N.; Wu, Z.; Zakaria, M.; Bilki, B.; Clarida, W.; Dilsiz, K.; Durgut, S.; Gandrajula, R. P.; Haytmyradov, M.; Khristenko, V.; Merlo, J.-P.; Mermerkaya, H.; Mestvirishvili, A.; Moeller, A.; Nachtman, J.; Ogul, H.; Onel, Y.; Ozok, F.; Penzo, A.; Snyder, C.; Tiras, E.; Wetzel, J.; Yi, K.; Anderson, I.; Barnett, B. A.; Blumenfeld, B.; Eminizer, N.; Fehling, D.; Feng, L.; Gritsan, A. V.; Maksimovic, P.; Martin, C.; Osherson, M.; Roskes, J.; Sady, A.; Sarica, U.; Swartz, M.; Xiao, M.; Xin, Y.; You, C.; Baringer, P.; Bean, A.; Benelli, G.; Bruner, C.; Kenny, R. P., III; Majumder, D.; Malek, M.; Murray, M.; Sanders, S.; Stringer, R.; Wang, Q.; Ivanov, A.; Kaadze, K.; Khalil, S.; Makouski, M.; Maravin, Y.; Mohammadi, A.; Saini, L. K.; Skhirtladze, N.; Toda, S.; Lange, D.; Rebassoo, F.; Wright, D.; Anelli, C.; Baden, A.; Baron, O.; Belloni, A.; Calvert, B.; Eno, S. C.; Ferraioli, C.; Gomez, J. A.; Hadley, N. J.; Jabeen, S.; Kellogg, R. G.; Kolberg, T.; Kunkle, J.; Lu, Y.; Mignerey, A. C.; Shin, Y. H.; Skuja, A.; Tonjes, M. B.; Tonwar, S. C.; Apyan, A.; Barbieri, R.; Baty, A.; Bierwagen, K.; Brandt, S.; Busza, W.; Cali, I. A.; Demiragli, Z.; Di Matteo, L.; Gomez Ceballos, G.; Goncharov, M.; Gulhan, D.; Iiyama, Y.; Innocenti, G. M.; Klute, M.; Kovalskyi, D.; Lai, Y. S.; Lee, Y.-J.; Levin, A.; Luckey, P. D.; Marini, A. C.; Mcginn, C.; Mironov, C.; Narayanan, S.; Niu, X.; Paus, C.; Ralph, D.; Roland, C.; Roland, G.; Salfeld-Nebgen, J.; Stephans, G. S. F.; Sumorok, K.; Varma, M.; Velicanu, D.; Veverka, J.; Wang, J.; Wang, T. W.; Wyslouch, B.; Yang, M.; Zhukova, V.; Dahmes, B.; Evans, A.; Finkel, A.; Gude, A.; Hansen, P.; Kalafut, S.; Kao, S. C.; Klapoetke, K.; Kubota, Y.; Lesko, Z.; Mans, J.; Nourbakhsh, S.; Ruckstuhl, N.; Rusack, R.; Tambe, N.; Turkewitz, J.; Acosta, J. G.; Oliveros, S.; Avdeeva, E.; Bloom, K.; Bose, S.; Claes, D. R.; Dominguez, A.; Fangmeier, C.; Gonzalez Suarez, R.; Kamalieddin, R.; Keller, J.; Knowlton, D.; Kravchenko, I.; Meier, F.; Monroy, J.; Ratnikov, F.; Siado, J. E.; Snow, G. R.; Alyari, M.; Dolen, J.; George, J.; Godshalk, A.; Harrington, C.; Iashvili, I.; Kaisen, J.; Kharchilava, A.; Kumar, A.; Rappoccio, S.; Roozbahani, B.; Alverson, G.; Barberis, E.; Baumgartel, D.; Chasco, M.; Hortiangtham, A.; Massironi, A.; Morse, D. M.; Nash, D.; Orimoto, T.; Teixeira De Lima, R.; Trocino, D.; Wang, R.-J.; Wood, D.; Zhang, J.; Hahn, K. A.; Kubik, A.; Mucia, N.; Odell, N.; Pollack, B.; Pozdnyakov, A.; Schmitt, M.; Stoynev, S.; Sung, K.; Trovato, M.; Velasco, M.; Brinkerhoff, A.; Dev, N.; Hildreth, M.; Jessop, C.; Karmgard, D. J.; Kellams, N.; Lannon, K.; Lynch, S.; Marinelli, N.; Meng, F.; Mueller, C.; Musienko, Y.; Pearson, T.; Planer, M.; Reinsvold, A.; Ruchti, R.; Smith, G.; Taroni, S.; Valls, N.; Wayne, M.; Wolf, M.; Woodard, A.; Antonelli, L.; Brinson, J.; Bylsma, B.; Durkin, L. S.; Flowers, S.; Hart, A.; Hill, C.; Hughes, R.; Ji, W.; Kotov, K.; Ling, T. Y.; Liu, B.; Luo, W.; Puigh, D.; Rodenburg, M.; Winer, B. L.; Wulsin, H. W.; Driga, O.; Elmer, P.; Hardenbrook, J.; Hebda, P.; Koay, S. A.; Lujan, P.; Marlow, D.; Medvedeva, T.; Mooney, M.; Olsen, J.; Palmer, C.; Piroué, P.; Saka, H.; Stickland, D.; Tully, C.; Zuranski, A.; Malik, S.; Barnes, V. E.; Benedetti, D.; Bortoletto, D.; Gutay, L.; Jha, M. K.; Jones, M.; Jung, K.; Miller, D. H.; Neumeister, N.; Radburn-Smith, B. C.; Shi, X.; Shipsey, I.; Silvers, D.; Sun, J.; Svyatkovskiy, A.; Wang, F.; Xie, W.; Xu, L.; Parashar, N.; Stupak, J.; Adair, A.; Akgun, B.; Chen, Z.; Ecklund, K. M.; Geurts, F. J. M.; Guilbaud, M.; Li, W.; Michlin, B.; Northup, M.; Padley, B. P.; Redjimi, R.; Roberts, J.; Rorie, J.; Tu, Z.; Zabel, J.; Betchart, B.; Bodek, A.; de Barbaro, P.; Demina, R.; Eshaq, Y.; Ferbel, T.; Galanti, M.; Garcia-Bellido, A.; Han, J.; Harel, A.; Hindrichs, O.; Khukhunaishvili, A.; Petrillo, G.; Tan, P.; Verzetti, M.; Arora, S.; Barker, A.; Chou, J. P.; Contreras-Campana, C.; Contreras-Campana, E.; Duggan, D.; Ferencek, D.; Gershtein, Y.; Gray, R.; Halkiadakis, E.; Hidas, D.; Hughes, E.; Kaplan, S.; Kunnawalkam Elayavalli, R.; Lath, A.; Nash, K.; Panwalkar, S.; Park, M.; Salur, S.; Schnetzer, S.; Sheffield, D.; Somalwar, S.; Stone, R.; Thomas, S.; Thomassen, P.; Walker, M.; Foerster, M.; Riley, G.; Rose, K.; Spanier, S.; York, A.; Bouhali, O.; Castaneda Hernandez, A.; Dalchenko, M.; De Mattia, M.; Delgado, A.; Dildick, S.; Eusebi, R.; Gilmore, J.; Kamon, T.; Krutelyov, V.; Mueller, R.; Osipenkov, I.; Pakhotin, Y.; Patel, R.; Perloff, A.; Rose, A.; Safonov, A.; Tatarinov, A.; Ulmer, K. A.; Akchurin, N.; Cowden, C.; Damgov, J.; Dragoiu, C.; Dudero, P. R.; Faulkner, J.; Kunori, S.; Lamichhane, K.; Lee, S. W.; Libeiro, T.; Undleeb, S.; Volobouev, I.; Appelt, E.; Delannoy, A. G.; Greene, S.; Gurrola, A.; Janjam, R.; Johns, W.; Maguire, C.; Mao, Y.; Melo, A.; Ni, H.; Sheldon, P.; Snook, B.; Tuo, S.; Velkovska, J.; Xu, Q.; Arenton, M. W.; Cox, B.; Francis, B.; Goodell, J.; Hirosky, R.; Ledovskoy, A.; Li, H.; Lin, C.; Neu, C.; Sinthuprasith, T.; Sun, X.; Wang, Y.; Wolfe, E.; Wood, J.; Xia, F.; Clarke, C.; Harr, R.; Karchin, P. E.; Kottachchi Kankanamge Don, C.; Lamichhane, P.; Sturdy, J.; Belknap, D. A.; Carlsmith, D.; Cepeda, M.; Dasu, S.; Dodd, L.; Duric, S.; Gomber, B.; Grothe, M.; Hall-Wilton, R.; Herndon, M.; Hervé, A.; Klabbers, P.; Lanaro, A.; Levine, A.; Long, K.; Loveless, R.; Mohapatra, A.; Ojalvo, I.; Perry, T.; Pierro, G. A.; Polese, G.; Ruggles, T.; Sarangi, T.; Savin, A.; Sharma, A.; Smith, N.; Smith, W. H.; Taylor, D.; Woods, N.

    2017-01-01

    This paper describes the CMS trigger system and its performance during Run 1 of the LHC. The trigger system consists of two levels designed to select events of potential physics interest from a GHz (MHz) interaction rate of proton-proton (heavy ion) collisions. The first level of the trigger is implemented in hardware, and selects events containing detector signals consistent with an electron, photon, muon, τ lepton, jet, or missing transverse energy. A programmable menu of up to 128 object-based algorithms is used to select events for subsequent processing. The trigger thresholds are adjusted to the LHC instantaneous luminosity during data taking in order to restrict the output rate to 100 kHz, the upper limit imposed by the CMS readout electronics. The second level, implemented in software, further refines the purity of the output stream, selecting an average rate of 400 Hz for offline event storage. The objectives, strategy and performance of the trigger system during the LHC Run 1 are described.

  14. Nature plus nurture: the triggering of multiple sclerosis.

    PubMed

    Wekerle, Hartmut

    2015-01-01

    Recent clinical and experimental studies indicate that multiple sclerosis develops as consequence of a failed interplay between genetic ("nature") and environmental ("nurture") factors. A large number of risk genes favour an autoimmune response against the body's own brain matter. New experimental data indicate that the actual trigger of this attack is however provided by an interaction of brain-specific immune cells with components of the regular commensal gut flora, the intestinal microbiota. This concept opens the way for new therapeutic approaches involving modulation of the microbiota by dietary or antibiotic regimens.

  15. Trigger readout electronics upgrade for the ATLAS Liquid Argon Calorimeters

    NASA Astrophysics Data System (ADS)

    Dinkespiler, B.

    2017-09-01

    The upgrade of the Large Hadron Collider (LHC) scheduled for the 2019-2020 shut-down period, referred to as Phase-I upgrade, will increase the instantaneous luminosity to about three times the design value. Since the current ATLAS trigger system does not allow sufficient increase of the trigger rate, an improvement of the trigger system is required. The Liquid Argon (LAr) Calorimeter read-out will therefore be modified to deliver digital trigger signals with a higher spatial granularity in order to improve the identification efficiencies of electrons, photons, tau, jets and missing energy, at high background rejection rates at the Level-1 trigger. The new trigger signals will be arranged in 34000 so-called Super Cells which achieves 5-10 times better granularity than the trigger towers currently used and allows an improved background rejection. The readout of the trigger signals will process the signal of the Super Cells at every LHC bunch-crossing at 12-bit precision and a frequency of 40 MHz. The data will be transmitted to the Back End using a custom serializer and optical converter and 5.12 Gb/s optical links. In order to verify the full functionality of the future Liquid Argon trigger system, a demonstrator set-up has been installed on the ATLAS detector and is operated in parallel to the regular ATLAS data taking during the LHC Run-2 in 2015 and 2016. Noise level and linearity on the energy measurement have been verified to be within our requirements. In addition, we have collected data from 13 TeV proton collisions during the LHC 2015 and 2016 runs, and have observed real pulses from the detector through the demonstrator system. The talk will give an overview of the Phase-I Upgrade of the ATLAS Liquid Argon Calorimeter readout and present the custom developed hardware including their role in real-time data processing and fast data transfer. This contribution will also report on the performance of the newly developed ASICs including their radiation tolerance

  16. Tidal Triggering of Microearthquakes Over an Eruption Cycle at 9°50'N East Pacific Rise

    NASA Astrophysics Data System (ADS)

    Tan, Yen Joe; Tolstoy, Maya; Waldhauser, Felix; Bohnenstiehl, DelWayne R.

    2018-02-01

    Studies have found that earthquake timing often correlates with tides at mid-ocean ridges and some terrestrial settings. Studies have also suggested that tidal triggering may preferentially happen when a region is critically stressed, making it a potential tool to forecast earthquakes and volcanic eruptions. We examine tidal triggering of ˜100,000 microearthquakes near 9°50'N East Pacific Rise recorded between October 2003 and January 2007, which encompasses an eruption in January 2006. This allows us to look at how tidal triggering signal varies over an eruption cycle to examine its utility as a forecasting tool. We find that tidal triggering signal is strong but does not vary systematically in the 2+ years leading up to the eruption. However, tidal triggering signal disappears immediately posteruption. Our findings suggest that tidal triggering variation may not be useful for forecasting mid-ocean ridge eruptions over a 2+ year timescale but might be useful over a longer timescale.

  17. Corporate sustainability: the environmental design and human resource management interface in healthcare settings.

    PubMed

    Sadatsafavi, Hessam; Walewski, John

    2013-01-01

    Purpose of the Paper: The purpose of this study is to provide healthcare organizations with a new perspective for developing strategies to enrich their human resource capabilities and improve their performance outcomes. The focus of this study is on leveraging the synergy between organizational management strategies and environmental design interventions. This paper proposes a framework for linking the built environment with the human resource management system of healthcare organizations. The framework focuses on the impact of the built environment regarding job attitudes and behaviors of healthcare workers. Research from the disciplines of strategic human resource management, resource-based view of firms, evidence-based design, and green building are utilized to develop the framework. The positive influence of human resource practices on job attitudes and behaviors of employees is one mechanism to improve organizational performance outcomes. Organizational psychologists suggest that human resource practices are effective because they convey that the organization values employee contributions and cares about their well-being. Attention to employee socio-emotional needs can be reciprocated with higher levels of motivation and commitment toward the organization. In line with these findings, healthcare environmental studies imply that physical settings and features can have a positive influence on job attitudes and the behavior of caregivers by providing for their physical and socio-emotional needs. Adding the physical environment as a complementary resource to the array of human resource practices creates synergy in improving caregivers' job attitudes and behaviors and enhances the human capital of healthcare firms. Staff, evidence-based design, interdisciplinary, modeling, perceived organizational supportPreferred Citation: Sadatsafavi, H., & Walewski, J. (2013). Corporate sustainability: The environmental design and human resource management interface in

  18. Analysis of Trigger Factors in Episodic Migraineurs Using a Smartphone Headache Diary Applications

    PubMed Central

    Park, Jeong-Wook; Chu, Min Kyung; Kim, Jae-Moon; Park, Sang-Gue; Cho, Soo-Jin

    2016-01-01

    Background Various stimuli can trigger migraines in susceptible individuals. We examined migraine trigger factors by using a smartphone headache diary application. Method Episodic migraineurs who agreed to participate in our study downloaded smartphone headache diary application, which was designed to capture the details regarding headache trigger factors and characteristics for 3 months. The participants were asked to access the smartphone headache diary application daily and to confirm the presence of a headache and input the types of trigger factors. Results Sixty-two participants kept diary entries until the end of the study. The diary data for 4,579 days were analyzed. In this data set, 1,099 headache days (336 migraines, 763 non-migraine headaches) were recorded; of these, 772 headache events had with trigger factors, and 327 events did not have trigger factors. The common trigger factors that were present on headache days included stress, fatigue, sleep deprivation, hormonal changes, and weather changes. The likelihood of a headache trigger was 57.7% for stress, 55.1% for sleep deprivation, 48.5% for fatigue, and 46.5% for any trigger. The headaches with trigger factors were associated with greater pain intensity (p<0.001), headache-related disability (p<0.001), abortive medication use (p = 0.02), and the proportion of migraine (p < 0.001), relative to those without trigger factors. Traveling (odd ratios [OR]: 6.4), hormonal changes (OR: 3.5), noise (OR: 2.8), alcohol (OR: 2.5), overeating (OR: 2.4), and stress (OR:1.8) were significantly associated with migraines compared to non-migraine headaches. The headaches that were associated with hormonal changes or noise were more often migraines, regardless of the preventive medication. The headaches due to stress, overeating, alcohol, and traveling were more often migraines without preventive medication, but it was not evident with preventive medication. Conclusion Smartphone headache diary application is an

  19. Analysis of Trigger Factors in Episodic Migraineurs Using a Smartphone Headache Diary Applications.

    PubMed

    Park, Jeong-Wook; Chu, Min Kyung; Kim, Jae-Moon; Park, Sang-Gue; Cho, Soo-Jin

    2016-01-01

    Various stimuli can trigger migraines in susceptible individuals. We examined migraine trigger factors by using a smartphone headache diary application. Episodic migraineurs who agreed to participate in our study downloaded smartphone headache diary application, which was designed to capture the details regarding headache trigger factors and characteristics for 3 months. The participants were asked to access the smartphone headache diary application daily and to confirm the presence of a headache and input the types of trigger factors. Sixty-two participants kept diary entries until the end of the study. The diary data for 4,579 days were analyzed. In this data set, 1,099 headache days (336 migraines, 763 non-migraine headaches) were recorded; of these, 772 headache events had with trigger factors, and 327 events did not have trigger factors. The common trigger factors that were present on headache days included stress, fatigue, sleep deprivation, hormonal changes, and weather changes. The likelihood of a headache trigger was 57.7% for stress, 55.1% for sleep deprivation, 48.5% for fatigue, and 46.5% for any trigger. The headaches with trigger factors were associated with greater pain intensity (p<0.001), headache-related disability (p<0.001), abortive medication use (p = 0.02), and the proportion of migraine (p < 0.001), relative to those without trigger factors. Traveling (odd ratios [OR]: 6.4), hormonal changes (OR: 3.5), noise (OR: 2.8), alcohol (OR: 2.5), overeating (OR: 2.4), and stress (OR:1.8) were significantly associated with migraines compared to non-migraine headaches. The headaches that were associated with hormonal changes or noise were more often migraines, regardless of the preventive medication. The headaches due to stress, overeating, alcohol, and traveling were more often migraines without preventive medication, but it was not evident with preventive medication. Smartphone headache diary application is an effective tool to assess migraine trigger

  20. NATIONAL SURVEY ON ENVIRONMENTAL MANAGEMENT OF ASTHMA

    EPA Science Inventory

    The National Survey on Environmental Management of Asthma is a nation-wide survey on awareness of and existing attitudes toward asthma and its environmental triggers. The survey will generate data which can be used as a benchmark to measure national awareness and action related ...

  1. Comparison of gait performance on different environmental settings for patients with chronic spinal cord injury.

    PubMed

    Olmos, L E; Freixes, O; Gatti, M A; Cozzo, D A; Fernandez, S A; Vila, C J; Agrati, P E; Rubel, I F

    2008-05-01

    Observational cross-section study. The objective of our study was to determine if the influence of a community environment would impact on ASIA D spinal cord injured (SCI) gait performance patients. Our main hypothesis is that an outdoor community environment may influence gait speed and endurance on community ambulating patients. Ten-Meter Walking (10MWT) and Six-Minute Walking (6MWT) tests were performed on community ambulating SCI research participants (n=18) in two different environmental conditions: (1) Experimental (indoors Gymnasium) and (2) Natural (community setting). Average gait speed and endurance values were obtained for the two different conditions and analyzed for statistical significance on the nonparametric two-tailed Wilcoxon signed rank test. While no difference was observed on the 10MWT we found an improvement on gait performance on the 6 MWT on a community setting. Our study showed mixed results on environmental influence on gait speed and endurance on ASIA D patient population. While there is no difference on the 10 MWT, there is an improvement on gait performance on the communitary 6MWT.

  2. The CMS trigger system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Khachatryan, Vardan

    This paper describes the CMS trigger system and its performance during Run 1 of the LHC. The trigger system consists of two levels designed to select events of potential physics interest from a GHz (MHz) interaction rate of proton-proton (heavy ion) collisions. The first level of the trigger is implemented in hardware, and selects events containing detector signals consistent with an electron, photon, muon, tau lepton, jet, or missing transverse energy. A programmable menu of up to 128 object-based algorithms is used to select events for subsequent processing. The trigger thresholds are adjusted to the LHC instantaneous luminosity during datamore » taking in order to restrict the output rate to 100 kHz, the upper limit imposed by the CMS readout electronics. The second level, implemented in software, further refines the purity of the output stream, selecting an average rate of 400 Hz for offline event storage. The objectives, strategy and performance of the trigger system during the LHC Run 1 are described.« less

  3. The CMS trigger system

    DOE PAGES

    Khachatryan, Vardan

    2017-01-24

    This paper describes the CMS trigger system and its performance during Run 1 of the LHC. The trigger system consists of two levels designed to select events of potential physics interest from a GHz (MHz) interaction rate of proton-proton (heavy ion) collisions. The first level of the trigger is implemented in hardware, and selects events containing detector signals consistent with an electron, photon, muon, tau lepton, jet, or missing transverse energy. A programmable menu of up to 128 object-based algorithms is used to select events for subsequent processing. The trigger thresholds are adjusted to the LHC instantaneous luminosity during datamore » taking in order to restrict the output rate to 100 kHz, the upper limit imposed by the CMS readout electronics. The second level, implemented in software, further refines the purity of the output stream, selecting an average rate of 400 Hz for offline event storage. The objectives, strategy and performance of the trigger system during the LHC Run 1 are described.« less

  4. Time Triggered Ethernet System Testing Means and Method

    NASA Technical Reports Server (NTRS)

    Smithgall, William Todd (Inventor); Hall, Brendan (Inventor); Varadarajan, Srivatsan (Inventor)

    2014-01-01

    Methods and apparatus are provided for evaluating the performance of a Time Triggered Ethernet (TTE) system employing Time Triggered (TT) communication. A real TTE system under test (SUT) having real input elements communicating using TT messages with output elements via one or more first TTE switches during a first time interval schedule established for the SUT. A simulation system is also provided having input simulators that communicate using TT messages via one or more second TTE switches with the same output elements during a second time interval schedule established for the simulation system. The first and second time interval schedules are off-set slightly so that messages from the input simulators, when present, arrive at the output elements prior to messages from the analogous real inputs, thereby having priority over messages from the real inputs and causing the system to operate based on the simulated inputs when present.

  5. Triggers for Autism: Genetic and Environmental Factors

    PubMed Central

    Matsuzaki, Hideo; Iwata, Keiko; Manabe, Takayuki; Mori, Norio

    2012-01-01

    This report reviews the research on the factors that cause autism. In several studies, these factors have been verified by reproducing them in autistic animal models. Clinical research has demonstrated that genetic and environmental factors play a major role in the development of autism. However, most cases are idiopathic, and no single factor can explain the trends in the pathology and prevalence of autism. At the time of this writing, autism is viewed more as a multi-factorial disorder. However, the existence of an unknown factor that may be common in all autistic cases cannot be ruled out. It is hoped that future biological studies of autism will help construct a new theory that can interpret the pathology of autism in a coherent manner. To achieve this, large-scale epidemiological research is essential. PMID:23650465

  6. Determination of trigger levels for groundwater quality in landfills located in historically human-impacted areas.

    PubMed

    Stefania, Gennaro A; Zanotti, Chiara; Bonomi, Tullia; Fumagalli, Letizia; Rotiroti, Marco

    2018-05-01

    Landfills are one of the most recurrent sources of groundwater contamination worldwide. In order to limit their impacts on groundwater resources, current environmental regulations impose the adoption of proper measures for the protection of groundwater quality. For instance, in the EU member countries, the calculation of trigger levels for identifying significant adverse environmental effects on groundwater generated by landfills is required by the Landfill Directive 99/31/EC. Although the derivation of trigger levels could be relatively easy when groundwater quality data prior to the construction of a landfill are available, it becomes challenging when these data are missing and landfills are located in areas that are already impacted by historical contamination. This work presents a methodology for calculating trigger levels for groundwater quality in landfills located in areas where historical contaminations have deteriorated groundwater quality prior to their construction. This method is based on multivariate statistical analysis and involves 4 steps: (a) implementation of the conceptual model, (b) landfill monitoring data collection, (c) hydrochemical data clustering and (d) calculation of the trigger levels. The proposed methodology was applied on a case study in northern Italy, where a currently used lined landfill is located downstream of an old unlined landfill and others old unmapped waste deposits. The developed conceptual model stated that groundwater quality deterioration observed downstream of the lined landfill is due to a degrading leachate plume fed by the upgradient unlined landfill. The methodology led to the determination of two trigger levels for COD and NH 4 -N, the former for a zone representing the background hydrochemistry (28 and 9 mg/L for COD and NH 4 -N, respectively), the latter for the zone impacted by the degrading leachate plume from the upgradient unlined landfill (89 and 83 mg/L for COD and NH 4 -N, respectively). Copyright

  7. Engaging novice teachers in semiotic inquiry: considering the environmental messages of school learning settings

    NASA Astrophysics Data System (ADS)

    Shapiro, Bonnie

    2014-12-01

    Katherine Fogelberg's insightful study of the messages of zoo signs describes the complex, sometimes contradictory nature of the messages they communicate. The construction and content of signs are influenced by institutional power. Fogelberg argues that the creation of zoo signage designed to inform the public can, through its messages, silence a perspective of care and compassion for animals. The research presented in the following article extends discussion about the value of critical considerations of cultural and institutional messages created and read in another type of setting designed to educate and inform, the school learning setting. The article reports on a project that engaged novice teachers in explorations of the nature and types of environmental messages found in learning settings. During our inquiry work together, novice teachers suggested areas of particular concern to them, and began to construct ideas about aspects of their work in which they plan to take action or engage in future inquiry. The research also reveals some of the challenges involved when novice educators first begin the process of engaging in semiotic interpretive readings of learning settings.

  8. Triggers for Violent Criminality in Patients With Psychotic Disorders.

    PubMed

    Sariaslan, Amir; Lichtenstein, Paul; Larsson, Henrik; Fazel, Seena

    2016-08-01

    Absolute and relative risks of violence are increased in patients with psychotic disorders, but the contribution of triggers for violent acts to these risks is uncertain. To examine whether a range of triggers for violent acts are associated with risks of violence in patients diagnosed with psychotic disorders and in individuals without a psychiatric diagnosis. Using a sample of all individuals born in Sweden between 1958 and 1988 (N = 3 123 724), we identified patients in the National Patient Register who were diagnosed with schizophrenia spectrum disorders (n = 34 903) and bipolar disorder (n = 29 692), as well as unaffected controls (n = 2 763 012). We then identified, within each subsample, persons who had experienced any of the following triggers for violent acts between January 1, 2001, and December 15, 2013: exposure to violence, parental bereavement, self-harm, traumatic brain injury, unintentional injuries, and substance intoxication. By using within-individual models, we conducted conditional logistic regression to compare the risk of the individual engaging in violent acts in the week following the exposure to a trigger with the risk during earlier periods of equivalent length. All time-invariant confounders (eg, genetic and early environmental influences) were controlled for by this research design and we further adjusted for time-varying sociodemographic factors. Adjusted odds ratios (aORs) of violent crime occurring in the week following the exposure to a trigger event compared with earlier periods. Among the sample of 2 827 607 individuals (1 492 186 male and 1 335 421 female), all of the examined trigger events were associated with increased risk of violent crime in the week following exposure. The largest 1-week absolute risk of violent crime was observed following exposure to violence (70-177 violent crimes per 10 000 persons). For most triggers, the relative risks did not vary significantly by diagnosis

  9. Asthma Triggers: Gain Control

    MedlinePlus

    ... Centers Asthma Contact Us Share Asthma Triggers: Gain Control Breathing Freely: Controlling Asthma Triggers This video features ... Air Quality: Biological Pollutants Help Your Child Gain Control Over Asthma Top of Page Molds About Molds ...

  10. Environmentally Sound Alternatives: Setting the Context.

    ERIC Educational Resources Information Center

    Chaudhary, Anil K.

    1989-01-01

    As former colonies struggle with economic development, consumerism competes with environmental awareness and concern. Developing countries should reject the models of the colonial past and create developmental strategies that preserve natural resources. (SK)

  11. Stability of model-based event-triggered control systems: a separation property

    NASA Astrophysics Data System (ADS)

    Hao, Fei; Yu, Hao

    2017-04-01

    To save resource of communication, this paper investigates the model-based event-triggered control systems. Two main problems are considered in this paper. One is, for given plant and model, to design event conditions to guarantee the stability of the systems. The other is to consider the effect of the model matrices on the stability. The results show that the closed-loop systems can be asymptotically stabilised with any model matrices in compact sets if the parameters in the event conditions are within the designed ranges. Then, a separation property of model-based event-triggered control is proposed. Namely, the design of the controller gain and the event condition can be separated from the selection of the model matrices. Based on this property, an adaption mechanism is introduced to the model-based event-triggered control systems, which can further improve the sampling performance. Finally, a numerical example is given to show the efficiency and feasibility of the developed results.

  12. Integrating hypermedia into the environmental education setting: Developing a program and evaluating its effect

    NASA Astrophysics Data System (ADS)

    Parker, Tehri Davenport

    1997-09-01

    This study designed, implemented, and evaluated an environmental education hypermedia program for use in a residential environmental education facility. The purpose of the study was to ascertain whether a hypermedia program could increase student knowledge and positive attitudes toward the environment and environmental education. A student/computer interface, based on the theory of social cognition, was developed to direct student interactions with the computer. A quasi-experimental research design was used. Students were randomly assigned to either the experimental or control group. The experimental group used the hypermedia program to learn about the topic of energy. The control group received the same conceptual information from a teacher/naturalist. An Environmental Awareness Quiz was administered to measure differences in the students' cognitive understanding of energy issues. Students participated in one on one interviews to discuss their attitudes toward the lesson and the overall environmental education experience. Additionally, members of the experimental group were tape recorded while they used the hypermedia program. These tapes were analyzed to identify aspects of the hypermedia program that promoted student learning. The findings of this study suggest that computers, and hypermedia programs, can be integrated into residential environmental education facilities, and can assist environmental educators in meeting their goals for students. The study found that the hypermedia program was as effective as the teacher/naturalist for teaching about environmental education material. Students who used the computer reported more positive attitudes toward the lesson on energy, and thought that they had learned more than the control group. Students in the control group stated that they did not learn as much as the computer group. The majority of students had positive attitudes toward the inclusion of computers in the camp setting, and stated that they were a good

  13. Environmental Setting and Implications on Water Quality, Upper Colorado River Basin, Colorado and Utah

    USGS Publications Warehouse

    Apodaca, Lori E.; Driver, Nancy E.; Stephens, Verlin C.; Spahr, Norman E.

    1995-01-01

    The Upper Colorado River Basin in Colorado and Utah is 1 of 60 study units selected for water-quality assessment as part of the U.S. Geological Survey's National Water-Quality Assessment program, which began full implementation in 1991. Understanding the environmental setting of the Upper Colorado River Basin study unit is important in evaluating water-quality issues in the basin. Natural and human factors that affect water quality in the basin are presented, including an overview of the physiography, climatic conditions, general geology and soils, ecoregions, population, land use, water management and use, hydrologic characteristics, and to the extent possible aquatic biology. These factors have substantial implications on water-quality conditions in the basin. For example, high concentrations of dissolved solids and selenium are present in the natural background water conditions of surface and ground water in parts ofthe basin. In addition, mining, urban, and agricultural land and water uses result in the presence of certain constituents in the surface and ground water of the basin that can detrimentally affect water quality. The environmental setting of the study unit provides a framework of the basin characteristics, which is important in the design of integrated studies of surface water, ground water, and biology.

  14. The big challenges in modeling human and environmental well-being.

    PubMed

    Tuljapurkar, Shripad

    2016-01-01

    This article is a selective review of quantitative research, historical and prospective, that is needed to inform sustainable development policy. I start with a simple framework to highlight how demography and productivity shape human well-being. I use that to discuss three sets of issues and corresponding challenges to modeling: first, population prehistory and early human development and their implications for the future; second, the multiple distinct dimensions of human and environmental well-being and the meaning of sustainability; and, third, inequality as a phenomenon triggered by development and models to examine changing inequality and its consequences. I conclude with a few words about other important factors: political, institutional, and cultural.

  15. Understanding Setting Events: What They Are and How to Identify Them

    ERIC Educational Resources Information Center

    Iovannone, Rose; Anderson, Cynthia; Scott, Terrance

    2017-01-01

    A functional behavior assessment is a process for identifying events in the environment that reliably precede (i.e., antecedents) and follow (i.e., consequences) problem behavior. This information is used to develop an intervention plan. There are two types of antecedents--triggers and setting events. Triggers are antecedent events that happen…

  16. Experiential benefits, place meanings, and environmental setting preferences between proximate and distant visitors to a national scenic trail.

    PubMed

    Kil, Namyun; Holland, Stephen M; Stein, Taylor V

    2015-05-01

    Effective management of conserved natural areas often requires a good understanding of recreation visitors who possess various values for those areas. This study examined differences in experiential benefits sought, place meanings, and environmental setting preferences between proximate and distant visitors to a publicly managed national scenic trail, which transects a variety of conserved public lands. Data were collected using on-site post-hike interviews with visitors at low, moderate, and high use trailheads. Proximate visitors sought mental and physical health more strongly than distant visitors, while distant visitors sought environmental exploration more strongly than proximate visitors. No significant difference in family bonding and achievement benefits existed between the two groups. Meanings related to place dependence, family identity, community identity, and place identity were more strongly ascribed by proximate visitors, and both groups rated ecological integrity meanings highly. Distant visitors showed stronger tendencies toward preferring a lesser level of trail development, lower level of encounters with other groups, and higher level of natural landscapes, which indicated an inclination toward natural settings. These findings indicate a managerially relevant role of the degree of proximity to environmental resources on individuals' recreation behaviors, meanings ascribed to the resources and setting conditions. Understanding differences and similarities between groups dichotomized by proximity to natural resources should advance more effective management of recreation and benefit opportunities for diverse visitor groups.

  17. Experiential Benefits, Place Meanings, and Environmental Setting Preferences Between Proximate and Distant Visitors to a National Scenic Trail

    NASA Astrophysics Data System (ADS)

    Kil, Namyun; Holland, Stephen M.; Stein, Taylor V.

    2015-05-01

    Effective management of conserved natural areas often requires a good understanding of recreation visitors who possess various values for those areas. This study examined differences in experiential benefits sought, place meanings, and environmental setting preferences between proximate and distant visitors to a publicly managed national scenic trail, which transects a variety of conserved public lands. Data were collected using on-site post-hike interviews with visitors at low, moderate, and high use trailheads. Proximate visitors sought mental and physical health more strongly than distant visitors, while distant visitors sought environmental exploration more strongly than proximate visitors. No significant difference in family bonding and achievement benefits existed between the two groups. Meanings related to place dependence, family identity, community identity, and place identity were more strongly ascribed by proximate visitors, and both groups rated ecological integrity meanings highly. Distant visitors showed stronger tendencies toward preferring a lesser level of trail development, lower level of encounters with other groups, and higher level of natural landscapes, which indicated an inclination toward natural settings. These findings indicate a managerially relevant role of the degree of proximity to environmental resources on individuals' recreation behaviors, meanings ascribed to the resources and setting conditions. Understanding differences and similarities between groups dichotomized by proximity to natural resources should advance more effective management of recreation and benefit opportunities for diverse visitor groups.

  18. Remote Dynamic Earthquake Triggering in Shale Gas Basins in Canada and Implications for Triggering Mechanisms

    NASA Astrophysics Data System (ADS)

    Harrington, Rebecca M.; Liu, Yajing; Wang, Bei; Kao, Honn; Yu, Hongyu

    2017-04-01

    Here we investigate the occurrence of remote dynamic triggering in three sedimentary basins in Canada where recent fluid injection activity is correlated with increasing numbers of earthquakes. In efforts to count as many small, local earthquakes as possible for the statistical test of triggering, we apply a multi-station matched-filter detection method to continuous waveforms to detect uncataloged local earthquakes in 10-day time windows surrounding triggering mainshocks occurring between 2013-2015 with an estimated local peak ground velocity exceeding 0.01 cm/s. We count the number of earthquakes in 24-hour bins and use a statistical p-value test to determine if the changes in seismicity levels after the mainshock waves have passed are statistically significant. The p-value tests show occurrences of triggering following transient stress perturbations of < 10 kPa at all three sites that suggest local faults may remain critically stressed over periods similar to the time frame of our study ( 2 years) or longer, potentially due to maintained high pore pressures in tight shale formations following injection. The time window over which seismicity rates change varies at each site, with more delayed triggering occurring at sites where production history is longer. The observations combined with new modeling results suggest that the poroelastic response of the medium may be the dominant factor influencing instantaneous triggering, particularly in low-permeability tight shales. At sites where production history is longer and permeabilities have been increased, both pore pressure diffusion and the poroelastic response of the medium may work together to promote both instantaneous and delayed triggering. Not only does the interplay of the poroelastic response of the medium and pore pressure diffusion have implications for triggering induced earthquakes near injection sites, but it may be a plausible explanation for observations of instantaneous and delayed earthquake

  19. Triggering soft bombs at the LHC

    DOE PAGES

    Knapen, Simon; Griso, Simone Pagan; Papucci, Michele; ...

    2017-08-18

    Very high multiplicity, spherically-symmetric distributions of soft particles, with p T ~ few×100 MeV, may be a signature of strongly-coupled hidden valleys that exhibit long, efficient showering windows. With traditional triggers, such ‘soft bomb’ events closely resemble pile-up and are therefore only recorded with minimum bias triggers at a very low efficiency. We demonstrate a proof-of-concept for a high-level triggering strategy that efficiently separates soft bombs from pile-up by searching for a ‘belt of fire’: a high density band of hits on the innermost layer of the tracker. Seeding our proposed high-level trigger with existing jet, missing transverse energy ormore » lepton hardware-level triggers, we show that net trigger efficiencies of order 10% are possible for bombs of mass several × 100 GeV. We also consider the special case that soft bombs are the result of an exotic decay of the 125 GeV Higgs. The fiducial rate for ‘Higgs bombs’ triggered in this manner is marginally higher than the rate achievable by triggering directly on a hard muon from associated Higgs production.« less

  20. Triggering soft bombs at the LHC

    NASA Astrophysics Data System (ADS)

    Knapen, Simon; Griso, Simone Pagan; Papucci, Michele; Robinson, Dean J.

    2017-08-01

    Very high multiplicity, spherically-symmetric distributions of soft particles, with p T ˜ few×100 MeV, may be a signature of strongly-coupled hidden valleys that exhibit long, efficient showering windows. With traditional triggers, such `soft bomb' events closely resemble pile-up and are therefore only recorded with minimum bias triggers at a very low efficiency. We demonstrate a proof-of-concept for a high-level triggering strategy that efficiently separates soft bombs from pile-up by searching for a `belt of fire': a high density band of hits on the innermost layer of the tracker. Seeding our proposed high-level trigger with existing jet, missing transverse energy or lepton hardware-level triggers, we show that net trigger efficiencies of order 10% are possible for bombs of mass several × 100 GeV. We also consider the special case that soft bombs are the result of an exotic decay of the 125 GeV Higgs. The fiducial rate for `Higgs bombs' triggered in this manner is marginally higher than the rate achievable by triggering directly on a hard muon from associated Higgs production.

  1. Triggering soft bombs at the LHC

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Knapen, Simon; Griso, Simone Pagan; Papucci, Michele

    Very high multiplicity, spherically-symmetric distributions of soft particles, with p T ~ few×100 MeV, may be a signature of strongly-coupled hidden valleys that exhibit long, efficient showering windows. With traditional triggers, such ‘soft bomb’ events closely resemble pile-up and are therefore only recorded with minimum bias triggers at a very low efficiency. We demonstrate a proof-of-concept for a high-level triggering strategy that efficiently separates soft bombs from pile-up by searching for a ‘belt of fire’: a high density band of hits on the innermost layer of the tracker. Seeding our proposed high-level trigger with existing jet, missing transverse energy ormore » lepton hardware-level triggers, we show that net trigger efficiencies of order 10% are possible for bombs of mass several × 100 GeV. We also consider the special case that soft bombs are the result of an exotic decay of the 125 GeV Higgs. The fiducial rate for ‘Higgs bombs’ triggered in this manner is marginally higher than the rate achievable by triggering directly on a hard muon from associated Higgs production.« less

  2. Neurotrophic factors switch between two signaling pathways that trigger axonal growth.

    PubMed

    Paveliev, Mikhail; Lume, Maria; Velthut, Agne; Phillips, Matthew; Arumäe, Urmas; Saarma, Mart

    2007-08-01

    Integration of multiple inputs from the extracellular environment, such as extracellular matrix molecules and growth factors, is a crucial process for cell function and information processing in multicellular organisms. Here we demonstrate that co-stimulation of dorsal root ganglion neurons with neurotrophic factors (NTFs) - glial-cell-line-derived neurotrophic factor, neurturin or nerve growth factor - and laminin leads to axonal growth that requires activation of Src family kinases (SFKs). A different, SFK-independent signaling pathway evokes axonal growth on laminin in the absence of the NTFs. By contrast, axonal branching is regulated by SFKs both in the presence and in the absence of NGF. We propose and experimentally verify a Boolean model of the signaling network triggered by NTFs and laminin. Our results demonstrate that NTFs provide an environmental cue that triggers a switch between separate pathways in the cell signaling network.

  3. A Review of Research on Environmental Education in Non-Traditional Settings in Turkey, 2000 and 2011

    ERIC Educational Resources Information Center

    Erdogan, Mehmet; Usak, Muhammet; Bahar, Mehmet

    2013-01-01

    The purpose of the present study was to collect and analyze the research on environmental education in non-traditional settings in Turkey undertaken with various subjects (e.g. students, graduates and teachers) and published over the years of 2000-2011. For systematic analysis, selected data-bases and journals were scrutinized across five…

  4. Output Consensus of Heterogeneous Linear Multi-Agent Systems by Distributed Event-Triggered/Self-Triggered Strategy.

    PubMed

    Hu, Wenfeng; Liu, Lu; Feng, Gang

    2016-09-02

    This paper addresses the output consensus problem of heterogeneous linear multi-agent systems. We first propose a novel distributed event-triggered control scheme. It is shown that, with the proposed control scheme, the output consensus problem can be solved if two matrix equations are satisfied. Then, we further propose a novel self-triggered control scheme, with which continuous monitoring is avoided. By introducing a fixed timer into both event- and self-triggered control schemes, Zeno behavior can be ruled out for each agent. The effectiveness of the event- and self-triggered control schemes is illustrated by an example.

  5. Wired and Wireless Camera Triggering with Arduino

    NASA Astrophysics Data System (ADS)

    Kauhanen, H.; Rönnholm, P.

    2017-10-01

    Synchronous triggering is an important task that allows simultaneous data capture from multiple cameras. Accurate synchronization enables 3D measurements of moving objects or from a moving platform. In this paper, we describe one wired and four wireless variations of Arduino-based low-cost remote trigger systems designed to provide a synchronous trigger signal for industrial cameras. Our wireless systems utilize 315 MHz or 434 MHz frequencies with noise filtering capacitors. In order to validate the synchronization accuracy, we developed a prototype of a rotating trigger detection system (named RoTriDeS). This system is suitable to detect the triggering accuracy of global shutter cameras. As a result, the wired system indicated an 8.91 μs mean triggering time difference between two cameras. Corresponding mean values for the four wireless triggering systems varied between 7.92 and 9.42 μs. Presented values include both camera-based and trigger-based desynchronization. Arduino-based triggering systems appeared to be feasible, and they have the potential to be extended to more complicated triggering systems.

  6. Seasonal movements and environmental triggers to fall migration of Sage Sparrows

    USGS Publications Warehouse

    Fesenmyer, K.A.; Knick, S.T.

    2011-01-01

    Post-breeding ecology of shrubland passerines prior to onset of migration is unknown relative to dynamics of breeding areas. We radiomarked and monitored 38 Sage Sparrows (Amphispiza belli ssp. nevadensis) at one site in Oregon and two in Nevada from September to mid-November 2007 to track local movements, estimate seasonal range sizes, and characterize weather patterns triggering onset of migration. Median area used by Sage Sparrows monitored between 3 and 18 days during or prior to migration was 14 ha; maximum daily movement was 15 km. Radio-marked Sage Sparrows at each location departed individually, rather than en masse, corresponding with passage of cold front weather systems. Conventional telemetry techniques limited our ability to monitor Sage Sparrows beyond pre-migratory periods and precluded detecting and tracking actual movements during migration. ?? 2011 by the Wilson Ornithological Society.

  7. Integrating Environmental Management of Asthma into Pediatric Health Care: What Worked and What Still Needs Improvement?

    PubMed

    Roberts, James R; Newman, Nicholas; McCurdy, Leyla E; Chang, Jane S; Salas, Mauro A; Eskridge, Bernard; De Ybarrondo, Lisa; Sandel, Megan; Mazur, Lynnette; Karr, Catherine J

    2016-12-01

    The National Environmental Education Foundation (NEEF) launched an initiative in 2005 to integrate environmental management of asthma into pediatric health care. This study, a follow-up to a 2013 study, evaluated the program's impact and assessed training results by 5 new faculty champions. We surveyed attendees at training sessions to measure knowledge and the likelihood of asking about and managing environmental triggers of asthma. To conduct the program evaluation, a workshop was held with the faculty champions and NEEF staff in which we identified major program benefits, as well as challenges and suggestions for the future. Trainee baseline knowledge of environmental triggers was low, but they reported robust improvement in environmental triggers knowledge and intention to recommend environmental management. The program has a broad, national scope, reaching more than 12 000 physicians, health care providers, and students, and some faculty champions successfully integrated materials into health record. Program barriers and future endeavors were identified.

  8. AIDS radio triggers.

    PubMed

    Elias, A M

    1991-07-01

    In April 1991, the Ethnic Communities' Council of NSW was granted funding under the Community AIDS Prevention and Education Program through the Department of Community Services and Health, to produce a series of 6x50 second AIDS radio triggers with a 10-second tag line for further information. The triggers are designed to disseminate culturally-sensitive information about HIV/AIDS in English, Italian, Greek, Spanish, Khmer, Turkish, Macedonian, Serbo-Croatian, Arabic, Cantonese, and Vietnamese, with the goal of increasing awareness and decreasing the degree of misinformation about HIV/AIDS among people of non-English-speaking backgrounds through radio and sound. The 6 triggers cover the denial that AIDS exists in the community, beliefs that words and feelings do not protect one from catching HIV, encouraging friends to be compassionate, compassion within the family, AIDS information for a young audience, and the provision of accurate and honest information on HIV/AIDS. The triggers are slated to be completed by the end of July 1991 and will be broadcast on all possible community, ethnic, and commercial radio networks across Australia. They will be available upon request in composite form with an information kit for use by health care professionals and community workers.

  9. Landslides triggered by the 8 October 2005 Kashmir earthquake

    USGS Publications Warehouse

    Owen, L.A.; Kamp, U.; Khattak, G.A.; Harp, E.L.; Keefer, D.K.; Bauer, M.A.

    2008-01-01

    The 8 October 2005 Kashmir earthquake triggered several thousand landslides. These were mainly rock falls and debris falls, although translational rock and debris slides also occurred. In addition, a sturzstrom (debris avalanche) comprising ??? 80??million m3 buried four villages and blocked streams to create two lakes. Although landsliding occurred throughout the region, covering an area of > 7500??km2, the failures were highly concentrated, associated with six geomorphic-geologic-anthropogenic settings, including natural failures in (1) highly fractured carbonate rocks comprising the lowest beds in the hanging wall of the likely earthquake fault; (2) Tertiary siliciclastic rocks along antecedent drainages that traverse the Hazara-Kashmir Syntaxis; (3) steep (> 50??) slopes comprising Precambrian and Lower Paleozoic rocks; (4) very steep (?? 50??) lower slopes of fluvially undercut Quaternary valley fills; and (5) ridges and spur crests. The sixth setting was associated with road construction. Extensive fissuring in many of the valley slopes together with the freshly mobilized landslide debris constitutes a potential hazard in the coming snowmelt and monsoon seasons. This study supports the view that earthquake-triggered landslides are highly concentrated in specific zones associated with the lithology, structure, geomorphology, topography, and human presence. ?? 2007 Elsevier B.V. All rights reserved.

  10. Phospholipids Trigger Cryptococcus neoformans Capsular Enlargement during Interactions with Amoebae and Macrophages

    PubMed Central

    Chrisman, Cara J.; Albuquerque, Patricia; Guimaraes, Allan J.; Nieves, Edward; Casadevall, Arturo

    2011-01-01

    A remarkable aspect of the interaction of Cryptococcus neoformans with mammalian hosts is a consistent increase in capsule volume. Given that many aspects of the interaction of C. neoformans with macrophages are also observed with amoebae, we hypothesized that the capsule enlargement phenomenon also had a protozoan parallel. Incubation of C. neoformans with Acanthamoeba castellanii resulted in C. neoformans capsular enlargement. The phenomenon required contact between fungal and protozoan cells but did not require amoeba viability. Analysis of amoebae extracts showed that the likely stimuli for capsule enlargement were protozoan polar lipids. Extracts from macrophages and mammalian serum also triggered cryptococcal capsular enlargement. C. neoformans capsule enlargement required expression of fungal phospholipase B, but not phospholipase C. Purified phospholipids, in particular, phosphatidylcholine, and derived molecules triggered capsular enlargement with the subsequent formation of giant cells. These results implicate phospholipids as a trigger for both C. neoformans capsule enlargement in vivo and exopolysaccharide production. The observation that the incubation of C. neoformans with phospholipids led to the formation of giant cells provides the means to generate these enigmatic cells in vitro. Protozoan- or mammalian-derived polar lipids could represent a danger signal for C. neoformans that triggers capsular enlargement as a non-specific defense mechanism against potential predatory cells. Hence, phospholipids are the first host-derived molecules identified to trigger capsular enlargement. The parallels apparent in the capsular response of C. neoformans to both amoebae and macrophages provide additional support for the notion that certain aspects of cryptococcal virulence emerged as a consequence of environmental interactions with other microorganisms such as protists. PMID:21637814

  11. CDF trigger interface board 'FRED'

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Campbell, M.; Dell' Orso, M.; Giannetti, P.

    1985-08-01

    We describe FASTBUS boards which interface sixteen different trigger interrupts to the Collider Detector Facility (CDF) data acquisition system. The boards are known to CDF by the acronym 'FRED'. The data acquisition scheme for CDF allows for up to 16 different parts of the detector, called 'Partitions', to run independently. Four partitions are reserved for physics runs and sophisticated calibration and debugging: they use the common Level 1 and Level 2 trigger logic and have access to information from all the components of the CDF detector. These four partitions are called ''CDF Partitions''. The remaining twelve partitions have no accessmore » to the common trigger logic and provide their own Level 1 and Level 2 signals: they are called ''Autonomous Partitions''. Fred collects and interprets signals from independent parts of the CDF trigger system and delivers Level 1 and Level 2 responses to the Trigger Supervisors (FASTBUS masters which control the data acquisition process in each partition).« less

  12. External triggering and triggered targeting strategies for drug delivery

    NASA Astrophysics Data System (ADS)

    Wang, Yanfei; Kohane, Daniel S.

    2017-06-01

    Drug delivery systems that are externally triggered to release drugs and/or target tissues hold considerable promise for improving the treatment of many diseases by minimizing nonspecific toxicity and enhancing the efficacy of therapy. These drug delivery systems are constructed from materials that are sensitive to a wide range of external stimuli, including light, ultrasound, electrical and magnetic fields, and specific molecules. The responsiveness conferred by these materials allows the release of therapeutics to be triggered on demand and remotely by a physician or patient. In this Review, we describe the rationales for such systems and the types of stimuli that can be deployed, and provide an outlook for the field.

  13. Global search of triggered non-volcanic tremor

    NASA Astrophysics Data System (ADS)

    Chao, Tzu-Kai Kevin

    Deep non-volcanic tremor is a newly discovered seismic phenomenon with low amplitude, long duration, and no clear P- and S-waves as compared with regular earthquake. Tremor has been observed at many major plate-boundary faults, providing new information about fault slip behaviors below the seismogenic zone. While tremor mostly occurs spontaneously (ambient tremor) or during episodic slow-slip events (SSEs), sometimes tremor can also be triggered during teleseismic waves of distance earthquakes, which is known as "triggered tremor". The primary focus of my Ph.D. work is to understand the physical mechanisms and necessary conditions of triggered tremor by systematic investigations in different tectonic regions. In the first chapter of my dissertation, I conduct a systematic survey of triggered tremor beneath the Central Range (CR) in Taiwan for 45 teleseismic earthquakes from 1998 to 2009 with Mw ≥ 7.5. Triggered tremors are visually identified as bursts of high-frequency (2-8 Hz), non-impulsive, and long-duration seismic energy that are coherent among many seismic stations and modulated by the teleseismic surface waves. A total of 9 teleseismic earthquakes has triggered clear tremor in Taiwan. The peak ground velocity (PGV) of teleseismic surface waves is the most important factor in determining tremor triggering potential, with an apparent threshold of ˜0.1 cm/s, or 7-8 kPa. However, such threshold is partially controlled by the background noise level, preventing triggered tremor with weaker amplitude from being observed. In addition, I find a positive correlation between the PGV and the triggered tremor amplitude, which is consistent with the prediction of the 'clock-advance' model. This suggests that triggered tremor can be considered as a sped-up occurrence of ambient tremor under fast loading from the passing surface waves. Finally, the incident angles of surface waves also play an important rule in controlling the tremor triggering potential. The next

  14. Environmental settings of the South Fork Iowa River basin, Iowa, and the Bogue Phalia basin, Mississippi, 2006-10

    USGS Publications Warehouse

    McCarthy, Kathleen A.; Rose, Claire E.; Kalkhoff, Stephen J.

    2012-01-01

    Studies of the transport and fate of agricultural chemicals in different environmental settings were conducted by the U.S. Geological Survey (USGS) National Water-Quality Assessment (NAWQA) Program's Agricultural Chemicals Team (ACT) at seven sites across the Nation, including the South Fork Iowa River basin in central Iowa and the Bogue Phalia basin in northwestern Mississippi. The South Fork Iowa River basin is representative of midwestern agriculture, where corn and soybeans are the predominant crops and a large percentage of the cultivated land is underlain by artificial drainage. The Bogue Phalia basin is representative of corn, soybean, cotton, and rice cropping in the humid, subtropical southeastern United States. Details of the environmental settings of these basins and the data-collection activities conducted by the USGS ACT over the 2006-10 study period are described in this report.

  15. Methods for automatic trigger threshold adjustment

    DOEpatents

    Welch, Benjamin J; Partridge, Michael E

    2014-03-18

    Methods are presented for adjusting trigger threshold values to compensate for drift in the quiescent level of a signal monitored for initiating a data recording event, thereby avoiding false triggering conditions. Initial threshold values are periodically adjusted by re-measuring the quiescent signal level, and adjusting the threshold values by an offset computation based upon the measured quiescent signal level drift. Re-computation of the trigger threshold values can be implemented on time based or counter based criteria. Additionally, a qualification width counter can be utilized to implement a requirement that a trigger threshold criterion be met a given number of times prior to initiating a data recording event, further reducing the possibility of a false triggering situation.

  16. Solar wind driving and substorm triggering

    NASA Astrophysics Data System (ADS)

    Newell, Patrick T.; Liou, Kan

    2011-03-01

    We compare solar wind driving and its changes for three data sets: (1) 4861 identifications of substorm onsets from satellite global imagers (Polar UVI and IMAGE FUV); (2) a similar number of otherwise random times chosen with a similar solar wind distribution (slightly elevated driving); (3) completely random times. Multiple measures of solar wind driving were used, including interplanetary magnetic field (IMF) Bz, the Kan-Lee electric field, the Borovsky function, and dΦMP/dt (all of which estimate dayside merging). Superposed epoch analysis verifies that the mean Bz has a northward turning (or at least averages less southward) starting 20 min before onset. We argue that the delay between IMF impact on the magnetopause and tail effects appearing in the ionosphere is about that long. The northward turning is not the effect of a few extreme events. The median field shows the same result, as do all other measures of solar wind driving. We compare the rate of northward turning to that observed after random times with slightly elevated driving. The subsequent reversion to mean is essentially the same between random elevations and substorms. To further verify this, we consider in detail the distribution of changes from the statistical peak (20 min prior to onset) to onset. For Bz, the mean change after onset is +0.14 nT (i.e., IMF becomes more northward), but the standard deviation is σ = 2.8 nT. Thus large changes in either direction are common. For EKL, the change is -15 nT km/s ± 830 nT km/s. Thus either a hypothesis predicting northward turnings or one predicting southward turnings would find abundant yet random confirming examples. Indeed, applying the Lyons et al. (1997) trigger criteria (excluding only the prior requirement of 22/30 min Bz < 0, which is often not valid for actual substorms) to these three sets of data shows that "northward turning triggers" occur in 23% of the random data, 24% of the actual substorms, and after 27% of the random elevations

  17. Are triggering rates of labquakes universal? Inferring triggering rates from incomplete information

    NASA Astrophysics Data System (ADS)

    Baró, Jordi; Davidsen, Jörn

    2017-12-01

    The acoustic emission activity associated with recent rock fracture experiments under different conditions has indicated that some features of event-event triggering are independent of the details of the experiment and the materials used and are often even indistinguishable from tectonic earthquakes. While the event-event triggering rates or aftershock rates behave pretty much identical for all rock fracture experiments at short times, this is not the case for later times. Here, we discuss how these differences can be a consequence of the aftershock identification method used and show that the true aftershock rates might have two distinct regimes. Specifically, tests on a modified Epidemic-Type Aftershock Sequence model show that the model rates cannot be correctly inferred at late times based on temporal information only if the activity rates or the branching ratio are high. We also discuss both the effect of the two distinct regimes in the aftershock rates and the effect of the background rate on the inter-event time distribution. Our findings should be applicable for inferring event-event triggering rates for many other types of triggering and branching processes as well.

  18. Error Recovery in the Time-Triggered Paradigm with FTT-CAN.

    PubMed

    Marques, Luis; Vasconcelos, Verónica; Pedreiras, Paulo; Almeida, Luís

    2018-01-11

    Data networks are naturally prone to interferences that can corrupt messages, leading to performance degradation or even to critical failure of the corresponding distributed system. To improve resilience of critical systems, time-triggered networks are frequently used, based on communication schedules defined at design-time. These networks offer prompt error detection, but slow error recovery that can only be compensated with bandwidth overprovisioning. On the contrary, the Flexible Time-Triggered (FTT) paradigm uses online traffic scheduling, which enables a compromise between error detection and recovery that can achieve timely recovery with a fraction of the needed bandwidth. This article presents a new method to recover transmission errors in a time-triggered Controller Area Network (CAN) network, based on the Flexible Time-Triggered paradigm, namely FTT-CAN. The method is based on using a server (traffic shaper) to regulate the retransmission of corrupted or omitted messages. We show how to design the server to simultaneously: (1) meet a predefined reliability goal, when considering worst case error recovery scenarios bounded probabilistically by a Poisson process that models the fault arrival rate; and, (2) limit the direct and indirect interference in the message set, preserving overall system schedulability. Extensive simulations with multiple scenarios, based on practical and randomly generated systems, show a reduction of two orders of magnitude in the average bandwidth taken by the proposed error recovery mechanism, when compared with traditional approaches available in the literature based on adding extra pre-defined transmission slots.

  19. Error Recovery in the Time-Triggered Paradigm with FTT-CAN

    PubMed Central

    Pedreiras, Paulo; Almeida, Luís

    2018-01-01

    Data networks are naturally prone to interferences that can corrupt messages, leading to performance degradation or even to critical failure of the corresponding distributed system. To improve resilience of critical systems, time-triggered networks are frequently used, based on communication schedules defined at design-time. These networks offer prompt error detection, but slow error recovery that can only be compensated with bandwidth overprovisioning. On the contrary, the Flexible Time-Triggered (FTT) paradigm uses online traffic scheduling, which enables a compromise between error detection and recovery that can achieve timely recovery with a fraction of the needed bandwidth. This article presents a new method to recover transmission errors in a time-triggered Controller Area Network (CAN) network, based on the Flexible Time-Triggered paradigm, namely FTT-CAN. The method is based on using a server (traffic shaper) to regulate the retransmission of corrupted or omitted messages. We show how to design the server to simultaneously: (1) meet a predefined reliability goal, when considering worst case error recovery scenarios bounded probabilistically by a Poisson process that models the fault arrival rate; and, (2) limit the direct and indirect interference in the message set, preserving overall system schedulability. Extensive simulations with multiple scenarios, based on practical and randomly generated systems, show a reduction of two orders of magnitude in the average bandwidth taken by the proposed error recovery mechanism, when compared with traditional approaches available in the literature based on adding extra pre-defined transmission slots. PMID:29324723

  20. The development of the ICF vestibular environmental scale.

    PubMed

    Whitney, Susan L; Alghadir, Ahmad; Alghwiri, Alia; Alshebber, Kefah M; Alshehri, Mohammed; Furman, Joseph M; Mueller, Martin; Grill, Eva

    2016-07-02

    People with vestibular disorders report changes in symptoms based on their environment with many situations increasing their symptoms. The purpose of this paper was to utilize the International Classification of Functioning Disability and Health (ICF) from the World Health Organization (WHO) to describe common environmental triggers for dizziness in persons living with balance and vestibular disorders. A multi-centre cross-sectional study was conducted with four different centres on three different continents, including patients from the United States (Pittsburgh), Germany (Munich), Jordan (Amman) and Saudi Arabia (Riyadh). Three hundred eighty one persons with vestibular disorders participated. A 9-item questionnaire (the Vestibular Environmental Scale) was developed from existing ICF items, which were compared to Dizziness Handicap Inventory (DHI) scores. Sixty-five percent of participants reported that "quick movements in the vicinity" increased symptoms, "crowds" at 45%, and "design of buildings, e.g. narrow hallways, stairs, elevators" at 42%. The "crowds" item was a good positive predictor of psychogenic vertigo (OR 1.8, 95% Confidence Interval 1.03-3.16), while "food" (OR 0.47, 95% Confidence Interval 0.17-1.29) and "light" (OR 0.41 95% Confidence Interval 0.23-0.75) were negative predictors of psychogenic vertigo. There also was a positive correlation between the number of triggers and DHI score (Spearman correlation coefficient 0.47, p < 0.0001). Sixty-eight percent of the subjects reported an increase in symptoms with between 1 and 4 environmental triggers. In our cross cultural sample, environmental triggers affect dizziness in persons living with balance and vestibular disorders. The use of items from the ICF of the WHO may help to promote cross cultural sharing of information in persons with dizziness.

  1. Integration of the Super Nova early warning system with the NOvA Trigger

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Habig, Alec; Zirnstein, Jan

    The NOvA experiment, with a baseline of 810km, samples Fermilab’s upgraded NuMI beam with a Near Detector on-site and a Far Detector (FD) at Ash River, MN, to observe oscillations of muon neutrinos. The 344,064 liquid scintillator-filled cells of the 14 kton FD provide high granularity of a large detector mass and enable us to also study non-accelerator based neutrinos with our Data Driven Trigger framework. This paper will focus on the real time integration of the SNEWS with the NOvA Trigger where we have set up an XML-RPC based messaging system to inject the SNEWS signal directly into ourmore » trigger. In conclusion, this presents a departure from the E-Mail based notification mechanism used by SNEWS in the past and allows NOvA more control over propagation and transmission timing.« less

  2. Integration of the Super Nova early warning system with the NOvA Trigger

    DOE PAGES

    Habig, Alec; Zirnstein, Jan

    2015-12-23

    The NOvA experiment, with a baseline of 810km, samples Fermilab’s upgraded NuMI beam with a Near Detector on-site and a Far Detector (FD) at Ash River, MN, to observe oscillations of muon neutrinos. The 344,064 liquid scintillator-filled cells of the 14 kton FD provide high granularity of a large detector mass and enable us to also study non-accelerator based neutrinos with our Data Driven Trigger framework. This paper will focus on the real time integration of the SNEWS with the NOvA Trigger where we have set up an XML-RPC based messaging system to inject the SNEWS signal directly into ourmore » trigger. In conclusion, this presents a departure from the E-Mail based notification mechanism used by SNEWS in the past and allows NOvA more control over propagation and transmission timing.« less

  3. Learning and Teaching as Emergent Features of Informal Settings: An Ethnographic Study in an Environmental Action Group

    ERIC Educational Resources Information Center

    Boyer, Leanna; Roth, Wolff-Michael

    2006-01-01

    Around the world, many people concerned with the state of the environment participate in environmental action groups. Much of their learning occurs informally, simply by participating in the everyday, ongoing collective life of the chosen group. Such settings provide unique opportunities for studying how people learn science in complex settings…

  4. Individual and Environmental Factors Influencing Adolescents' Dietary Behavior in Low- and Middle-Income Settings.

    PubMed

    Verstraeten, Roosmarijn; Leroy, Jef L; Pieniak, Zuzanna; Ochoa-Avilès, Angélica; Holdsworth, Michelle; Verbeke, Wim; Maes, Lea; Kolsteren, Patrick

    2016-01-01

    Given the public health importance of improving dietary behavior in chronic disease prevention in low- and middle-income countries it is crucial to understand the factors influencing dietary behavior in these settings. This study tested the validity of a conceptual framework linking individual and environmental factors to dietary behavior among Ecuadorian adolescents aged 10-16 years. A cross-sectional survey was conducted in 784 school-going Ecuadorian adolescents in urban and rural Southern Ecuador. Participants provided data on socio-economic status, anthropometry, dietary behavior and its determining factors. The relationships between individual (perceived benefits and barriers, self-efficacy, habit strength, and a better understanding of healthy food) and environmental factors (physical environment: accessibility to healthy food; social environment: parental permissiveness and school support), and their association with key components of dietary behavior (fruit and vegetables, sugary drinks, breakfast, and unhealthy snack intake) were assessed using structural equation modeling. The conceptual model performed well for each component of eating behavior, indicating acceptable goodness-of-fit for both the measurement and structural models. Models for vegetable intake and unhealthy snacking showed significant and direct effects of individual factors (perceived benefits). For breakfast and sugary drink consumption, there was a direct and positive association with socio-environmental factors (school support and parental permissiveness). Access to healthy food was associated indirectly with all eating behaviors (except for sugary drink intake) and this effect operated through socio-environmental (parental permissiveness and school support) and individual factors (perceived benefits). Our study demonstrated that key components of adolescents' dietary behaviors are influenced by a complex interplay of individual and environmental factors. The findings indicate that the

  5. Tremors Triggered along the Queen Charlotte Fault

    NASA Astrophysics Data System (ADS)

    Aiken, C.; Peng, Z.; Chao, K.

    2012-12-01

    In the past decade, deep tectonic tremors have been observed in numerous tectonic environments surrounding the Pacific and Caribbean plates. In these regions, tremors triggered by both regional and distant earthquakes have also been observed. Despite the ubiquitous observations of triggered tremors, tremors triggered in differing strike-slip environments are less understood. Here, we conduct a preliminary search of tremors triggered by teleseismic earthquakes along the transpressive Queen Charlotte Fault (QCF) located between the Cascadia subduction zone and Alaska. Tectonic tremors have not been previously reported along the QCF. We select teleseismic earthquakes during the 1990-2012 period as having magnitude M ≥ 6.5 and occurring at least 1,000 km away from the region. We reduce the number of mainshocks by selecting those that generate greater than 1 kPa dynamic stress estimated from surface-wave magnitude equations [e.g. van der Elst and Brodsky, 2010]. Our mainshock waveforms are retrieved from the Canadian National Seismograph Network (CNSN), processed, and filtered for triggered tremor observations. We characterize triggered tremors as high-frequency signals visible among several stations and coincident with broadband surface wave peaks. So far, we have found tremors triggered along the QCF by surface waves of five great earthquakes - the 2002/11/03 Mw7.9 Denali Fault, 2004/12/26 Mw9.0 Sumatra, 2010/02/27 Mw8.8 Chile, 2011/03/11 Mw9.0 Japan, and 2012/04/11 Mw8.6 Sumatra earthquakes. We compare our results to tremors triggered by teleseismic earthquakes on strike-slip faults in central and southern California, as well as Cuba [Peng et al., 2012]. Among strike-slip faults in these regions, we also compare triggered tremor amplitudes to peak ground velocities from the mainshocks and compute dynamic stresses to determine a triggering threshold for the QCF. We find that in most cases tremors in the QCF are triggered primarily by the Love waves, and additional

  6. Prediction of earthquake-triggered landslide event sizes

    NASA Astrophysics Data System (ADS)

    Braun, Anika; Havenith, Hans-Balder; Schlögel, Romy

    2016-04-01

    Seismically induced landslides are a major environmental effect of earthquakes, which may significantly contribute to related losses. Moreover, in paleoseismology landslide event sizes are an important proxy for the estimation of the intensity and magnitude of past earthquakes and thus allowing us to improve seismic hazard assessment over longer terms. Not only earthquake intensity, but also factors such as the fault characteristics, topography, climatic conditions and the geological environment have a major impact on the intensity and spatial distribution of earthquake induced landslides. We present here a review of factors contributing to earthquake triggered slope failures based on an "event-by-event" classification approach. The objective of this analysis is to enable the short-term prediction of earthquake triggered landslide event sizes in terms of numbers and size of the affected area right after an earthquake event occurred. Five main factors, 'Intensity', 'Fault', 'Topographic energy', 'Climatic conditions' and 'Surface geology' were used to establish a relationship to the number and spatial extend of landslides triggered by an earthquake. The relative weight of these factors was extracted from published data for numerous past earthquakes; topographic inputs were checked in Google Earth and through geographic information systems. Based on well-documented recent earthquakes (e.g. Haiti 2010, Wenchuan 2008) and on older events for which reliable extensive information was available (e.g. Northridge 1994, Loma Prieta 1989, Guatemala 1976, Peru 1970) the combination and relative weight of the factors was calibrated. The calibrated factor combination was then applied to more than 20 earthquake events for which landslide distribution characteristics could be cross-checked. One of our main findings is that the 'Fault' factor, which is based on characteristics of the fault, the surface rupture and its location with respect to mountain areas, has the most important

  7. Interplay of diverse environmental settings and their influence on the plankton community off Myanmar during the Spring Intermonsoon

    NASA Astrophysics Data System (ADS)

    Jyothibabu, R.; Win, Ni Ni; Shenoy, D. M.; Swe, U. Tint; Pratik, M.; Thwin, Swe; Jagadeesan, L.

    2014-11-01

    The northern Andaman Sea including the Myanmar waters is one of the least studied regions of the northern Indian Ocean. The freshwater and suspended sediments carried by Ayeyawady/Irrawaddy, the peculiar surface circulation, coastline morphology and shallow bathymetry in the Gulf of Mottama facilitate several diverse environmental settings in the study region. In order to understand the environmental settings and their linkages to the plankton community in the study region, this paper combined in situ data of 'First India-Myanmar Joint Oceanographic Expedition' with satellite oceanography observations. The study period was the Spring Intermonsoon (March-May), which was characterized by high tidal activity in the Gulf of Mottama region (tidal height 6-8 m) causing strong tidal currents and re-suspension of sediments. The tidal currents and eastward advection of Ayeyawady influx caused the lowest salinity, highest concentration of nutrients, suspended sediments and chlorophyll a in the Gulf of Mottama region. Conversely, high salinity, highest temperature, lowest nutrients and suspended sediments prevalent in the offshore waters of the northern Andaman Sea induced a massive bloom of Trichodesmium erythraeum, which was mostly in the declining phase during the observation. The in situ and satellite remote sensing data clearly showed that the T. erythraeum bloom observed in the offshore waters was closely linked to a warm core eddy. The decomposition of the bloom favored swarms of siphonophores and hydromedusae through a trophic link involving copepods and appendicularians. Aided by satellite remote sensing data and multivariate statistical tools, five diverse environmental settings have been identified in the study domain. The analysis showed a close coupling between phytoplankton biomass and nutrients with their higher values in the Gulf of Mottama, off Rakhine, Ayeyawady and Thanintharyi region as compared to the offshore waters in the northern Andaman Sea. The

  8. Application of Fault Management Theory to the Quantitive Selection of a Launch Vehicle Abort Trigger Suite

    NASA Technical Reports Server (NTRS)

    Lo, Yunnhon; Johnson, Stephen B.; Breckenridge, Jonathan T.

    2014-01-01

    SHM/FM theory has been successfully applied to the selection of the baseline set Abort Triggers for the NASA SLS center dot Quantitative assessment played a useful role in the decision process ? M&FM, which is new within NASA MSFC, required the most "new" work, as this quantitative analysis had never been done before center dot Required development of the methodology and tool to mechanize the process center dot Established new relationships to the other groups ? The process is now an accepted part of the SLS design process, and will likely be applied to similar programs in the future at NASA MSFC ? Future improvements center dot Improve technical accuracy ?Differentiate crew survivability due to an abort, vs. survivability even no immediate abort occurs (small explosion with little debris) ?Account for contingent dependence of secondary triggers on primary triggers ?Allocate "? LOC Benefit" of each trigger when added to the previously selected triggers. center dot Reduce future costs through the development of a specialized tool ? Methodology can be applied to any manned/unmanned vehicle, in space or terrestrial

  9. National Environmental Leadership Award in Asthma Management

    EPA Pesticide Factsheets

    The National Asthma Awards recognizes health plans, healthcare providers and communities in action that demonstrate an environmental component to address asthma triggers, collaborate with others and save healthcare dollars with their programming.

  10. Rainfall thresholds for the activation of shallow landslides in the Italian Alps: the role of environmental conditioning factors

    NASA Astrophysics Data System (ADS)

    Palladino, M. R.; Viero, A.; Turconi, L.; Brunetti, M. T.; Peruccacci, S.; Melillo, M.; Luino, F.; Deganutti, A. M.; Guzzetti, F.

    2018-02-01

    The aim of the present work is to investigate the role exerted by selected environmental factors in the activation of rainfall-triggered shallow landslides and to identify site-specific rainfall thresholds. The study concerns the Italian Alps. The region is exposed to widespread slope instability phenomena due to its geological, morphological and climatic features. Furthermore, the high level of anthropization that characterizes wide portions of the territory increases the associated risk. Hence, the analysis of potential predisposing factors influencing landslides triggering is worthwhile to improve the current prediction skills and to enhance the preparedness and the response to these natural hazards. During the last years, the Italian National Research Council's Research Institute for Hydro-geological Protection (CNR-IRPI) has contributed to the analysis of triggering conditions for rainfall-induced landslides in the framework of a national project. The project, funded by the National Department for Civil Protection (DPC), focuses on the identification of the empirical rainfall thresholds for the activation of shallow landslides in Italy. The first outcomes of the project reveal a certain variability of the pluviometric conditions responsible for the mass movements activation, when different environmental settings are compared. This variability is probably related to the action of local environmental factors, such as lithology, climatic regime or soil characteristics. Based on this hypothesis, the present study aims to identify separated domains within the Italian Alps, where different triggering conditions exist and different countermeasures are needed for risk prevention. For this purpose, we collected information concerning 511 landslides activated in the period 2000-2012 and reconstructed 453 rainfall events supposed to be responsible for the activations. Then, we selected a set of thematic maps to represent the hypothesised landslide conditioning factors

  11. Rate of Change in Lake Level and its Impact on Reservoir-triggered Seismicity

    NASA Astrophysics Data System (ADS)

    Simpson, D. W.

    2017-12-01

    With recent interest in increased seismicity related to fluid injection, it is useful to review cases of reservoir-triggered earthquakes to explore common characteristics and seek ways to mitigate the influence of anthropogenic impacts. Three reservoirs - Koyna, India; Nurek, Tajikistan; and Aswan, Egypt - are well-documented cases of triggered earthquakes with recorded time series of seismicity and water levels that extend for more than 30 years. The geological setting, regional tectonics and modes of reservoir utilization, along with the characteristics of the reservoir-seismicity interaction, are distinctly different in each of these three cases. Similarities and differences between these three cases point to regional and local geological and hydrological structures and the rate of changes in reservoir water level as important factors controlling the presence and timing of triggered seismicity. In a manner similar to the way in which the rate of fluid injection influences injection-related seismicity, the rate of change in reservoir water level is a significant factor in determining whether or not reservoir-triggered seismicity occurs. The high rate of annual water level rise may be important in sustaining the exceptionally long sequence of earthquakes at Koyna. In addition to the rate of filling being a determining factor in whether or not earthquakes are triggered, changes in the rate of filling may influence the time of occurrence of individual earthquakes.

  12. Changes in blood flow and cellular metabolism at a myofascial trigger point with trigger point release (ischemic compression): a proof-of-principle pilot study

    PubMed Central

    Moraska, Albert F.; Hickner, Robert C.; Kohrt, Wendy M.; Brewer, Alan

    2012-01-01

    Objective To demonstrate proof-of-principle measurement for physiological change within an active myofascial trigger point (MTrP) undergoing trigger point release (ischemic compression). Design Interstitial fluid was sampled continuously at a trigger point before and after intervention. Setting A biomedical research clinic at a university hospital. Participants Two subjects from a pain clinic presenting with chronic headache pain. Interventions A single microdialysis catheter was inserted into an active MTrP of the upper trapezius to allow for continuous sampling of interstitial fluid before and after application of trigger point therapy by a massage therapist. Main Outcome Measures Procedural success, pain tolerance, feasibility of intervention during sample collection, determination of physiologically relevant values for local blood flow, as well as glucose and lactate concentrations. Results Both patients tolerated the microdialysis probe insertion into the MTrP and treatment intervention without complication. Glucose and lactate concentrations were measured in the physiological range. Following intervention, a sustained increase in lactate was noted for both subjects. Conclusions Identifying physiological constituents of MTrP’s following intervention is an important step toward understanding pathophysiology and resolution of myofascial pain. The present study forwards that aim by showing proof-of-concept for collection of interstitial fluid from an MTrP before and after intervention can be accomplished using microdialysis, thus providing methodological insight toward treatment mechanism and pain resolution. Of the biomarkers measured in this study, lactate may be the most relevant for detection and treatment of abnormalities in the MTrP. PMID:22975226

  13. Investigation of index finger triggering force using a cadaver experiment: Effects of trigger grip span, contact location, and internal tendon force.

    PubMed

    Chang, Joonho; Freivalds, Andris; Sharkey, Neil A; Kong, Yong-Ku; Mike Kim, H; Sung, Kiseok; Kim, Dae-Min; Jung, Kihyo

    2017-11-01

    A cadaver study was conducted to investigate the effects of triggering conditions (trigger grip span, contact location, and internal tendon force) on index finger triggering force and the force efficiency of involved tendons. Eight right human cadaveric hands were employed, and a motion simulator was built to secure and control the specimens. Index finger triggering forces were investigated as a function of different internal tendon forces (flexor digitorum profundus + flexor digitorum superficialis = 40, 70, and 100 N), trigger grip spans (40, 50, and 60 mm), and contact locations between the index finger and a trigger. Triggering forces significantly increased when internal tendon forces increased from 40 to 100 N. Also, trigger grip spans and contact locations had significant effects on triggering forces; maximum triggering forces were found at a 50 mm span and the most proximal contact location. The results revealed that only 10-30% of internal tendon forces were converted to their external triggering forces. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Intraplate triggered earthquakes: Observations and interpretation

    USGS Publications Warehouse

    Hough, S.E.; Seeber, L.; Armbruster, J.G.

    2003-01-01

    We present evidence that at least two of the three 1811-1812 New Madrid, central United States, mainshocks and the 1886 Charleston, South Carolina, earthquake triggered earthquakes at regional distances. In addition to previously published evidence for triggered earthquakes in the northern Kentucky/southern Ohio region in 1812, we present evidence suggesting that triggered events might have occurred in the Wabash Valley, to the south of the New Madrid Seismic Zone, and near Charleston, South Carolina. We also discuss evidence that earthquakes might have been triggered in northern Kentucky within seconds of the passage of surface waves from the 23 January 1812 New Madrid mainshock. After the 1886 Charleston earthquake, accounts suggest that triggered events occurred near Moodus, Connecticut, and in southern Indiana. Notwithstanding the uncertainty associated with analysis of historical accounts, there is evidence that at least three out of the four known Mw 7 earthquakes in the central and eastern United States seem to have triggered earthquakes at distances beyond the typically assumed aftershock zone of 1-2 mainshock fault lengths. We explore the possibility that remotely triggered earthquakes might be common in low-strain-rate regions. We suggest that in a low-strain-rate environment, permanent, nonelastic deformation might play a more important role in stress accumulation than it does in interplate crust. Using a simple model incorporating elastic and anelastic strain release, we show that, for realistic parameter values, faults in intraplate crust remain close to their failure stress for a longer part of the earthquake cycle than do faults in high-strain-rate regions. Our results further suggest that remotely triggered earthquakes occur preferentially in regions of recent and/or future seismic activity, which suggests that faults are at a critical stress state in only some areas. Remotely triggered earthquakes may thus serve as beacons that identify regions of

  15. Microfabricated triggered vacuum switch

    DOEpatents

    Roesler, Alexander W [Tijeras, NM; Schare, Joshua M [Albuquerque, NM; Bunch, Kyle [Albuquerque, NM

    2010-05-11

    A microfabricated vacuum switch is disclosed which includes a substrate upon which an anode, cathode and trigger electrode are located. A cover is sealed over the substrate under vacuum to complete the vacuum switch. In some embodiments of the present invention, a metal cover can be used in place of the trigger electrode on the substrate. Materials used for the vacuum switch are compatible with high vacuum, relatively high temperature processing. These materials include molybdenum, niobium, copper, tungsten, aluminum and alloys thereof for the anode and cathode. Carbon in the form of graphitic carbon, a diamond-like material, or carbon nanotubes can be used in the trigger electrode. Channels can be optionally formed in the substrate to mitigate against surface breakdown.

  16. Environmentally triggered genomic plasticity and capsular polysaccharide formation are involved in increased ethanol and acetic acid tolerance in Kozakia baliensis NBRC 16680.

    PubMed

    Brandt, Julia U; Born, Friederike-Leonie; Jakob, Frank; Vogel, Rudi F

    2017-08-10

    Kozakia baliensis NBRC 16680 secretes a gum-cluster derived heteropolysaccharide and forms a surface pellicle composed of polysaccharides during static cultivation. Furthermore, this strain exhibits two colony types on agar plates; smooth wild-type (S) and rough mutant colonies (R). This switch is caused by a spontaneous transposon insertion into the gumD gene of the gum-cluster, resulting in a heteropolysaccharide secretion deficient, rough phenotype. To elucidate, whether this is a directed switch triggered by environmental factors, we checked the number of R and S colonies under different growth conditions including ethanol and acetic acid supplementation. Furthermore, we investigated the tolerance of R and S strains against ethanol and acetic acid in shaking and static growth experiments. To get new insights into the composition and function of the pellicle polysaccharide, the polE gene of the R strain was additionally deleted, as it was reported to be involved in pellicle formation in other acetic acid bacteria. The number of R colonies was significantly increased upon growth on acetic acid and especially ethanol. The morphological change from K. baliensis NBRC 16680 S to R strain was accompanied by changes in the sugar contents of the produced pellicle EPS. The R:ΔpolE mutant strain was not able to form a regular pellicle anymore, but secreted an EPS into the medium, which exhibited a similar sugar monomer composition as the pellicle polysaccharide isolated from the R strain. The R strain had a markedly increased tolerance towards acetic acid and ethanol compared to the other NBRC 16680 strains (S, R:ΔpolE). A relatively high intrinsic acetic acid tolerance was also observable for K. baliensis DSM 14400 T , which might indicate diverse adaptation mechanisms of different K. baliensis strains in altering natural habitats. The results suggest that the genetically triggered R phenotype formation is directly related to increased acetic acid and ethanol

  17. Tinnitus-provoking salicylate treatment triggers social impairments in mice.

    PubMed

    Guitton, Matthieu J

    2009-09-01

    Tinnitus (perception of sound in silence) strongly affects the quality of life of sufferers. Tinnitus sufferers and their relatives frequently complain about major social impairments. However, it is not known whether this impairment directly results from the occurrence of tinnitus or is the indirect expression of a preexisting psychological vulnerability. Using the well-characterized animal model of salicylate-induced tinnitus, we investigate in mice whether the occurrence of tinnitus can trigger social impairments. Experiments were performed on 32 male Balb/C mice. Tinnitus was induced in mice using salicylate treatment. Social behavior was assessed in experimental and control animals using social interaction paradigm. Interaction time, number of social events, and number of nonsocial events were assessed in all animals. We demonstrate for the first time that treatment known to induce tinnitus triggers complex social impairments in mice. While salicylate-treated animals present a massive decrease in their overall social interactions compared to control untreated animals, they also display a paradoxal increase in the number of conspecific followings. Tinnitus can thus trigger a complex set of modifications of behavior, which will not only find their expression at the individual level, but also at the social level. Our results suggest that tinnitus can directly be a cause of psychosocial impairment in human and have strong implications for the clinical management of tinnitus sufferers.

  18. The LHCb trigger and its upgrade

    NASA Astrophysics Data System (ADS)

    Dziurda, A.; LHCb Trigger Group

    2016-07-01

    The current LHCb trigger system consists of a hardware level, which reduces the LHC inelastic collision rate of 30 MHz, at which the entire detector is read out. In a second level, implemented in a farm of 20 k parallel-processing CPUs, the event rate is reduced to about 5 kHz. We review the performance of the LHCb trigger system during Run I of the LHC. Special attention is given to the use of multivariate analyses in the High Level Trigger. The major bottleneck for hadronic decays is the hardware trigger. LHCb plans a major upgrade of the detector and DAQ system in the LHC shutdown of 2018, enabling a purely software based trigger to process the full 30 MHz of inelastic collisions delivered by the LHC. We demonstrate that the planned architecture will be able to meet this challenge.

  19. More Than a Text Message: Dismantling Digital Triggers to Curate Behavior Change in Patient-Centered Health Interventions.

    PubMed

    Muench, Frederick; Baumel, Amit

    2017-05-26

    Digital triggers such as text messages, emails, and push alerts are designed to focus an individual on a desired goal by prompting an internal or external reaction at the appropriate time. Triggers therefore have an essential role in engaging individuals with digital interventions delivered outside of traditional health care settings, where other events in daily lives and fluctuating motivation to engage in effortful behavior exist. There is an emerging body of literature examining the use of digital triggers for short-term action and longer-term behavior change. However, little attention has been given to understanding the components of digital triggers. Using tailoring as an overarching framework, we separated digital triggers into 5 primary components: (1) who (sender), (2) how (stimulus type, delivery medium, heterogeneity), (3) when (delivered), (4) how much (frequency, intensity), and (5) what (trigger's target, trigger's structure, trigger's narrative). We highlighted key considerations when tailoring each component and the pitfalls of ignoring common mistakes, such as alert fatigue and habituation. As evidenced throughout the paper, there is a broad literature base from which to draw when tailoring triggers to curate behavior change in health interventions. More research is needed, however, to examine differences in efficacy based on component tailoring, to best use triggers to facilitate behavior change over time, and to keep individuals engaged in physical and mental health behavior change efforts. Dismantling digital triggers into their component parts and reassembling them according to the gestalt of one's change goals is the first step in this development work. ©Frederick Muench, Amit Baumel. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 26.05.2017.

  20. Development, Integration and Testing of Automated Triggering Circuit for Hybrid DC Circuit Breaker

    NASA Astrophysics Data System (ADS)

    Kanabar, Deven; Roy, Swati; Dodiya, Chiragkumar; Pradhan, Subrata

    2017-04-01

    A novel concept of Hybrid DC circuit breaker having combination of mechanical switch and static switch provides arc-less current commutation into the dump resistor during quench in superconducting magnet operation. The triggering of mechanical and static switches in Hybrid DC breaker can be automatized which can effectively reduce the overall current commutation time of hybrid DC circuit breaker and make the operation independent of opening time of mechanical switch. With this view, a dedicated control circuit (auto-triggering circuit) has been developed which can decide the timing and pulse duration for mechanical switch as well as static switch from the operating parameters. This circuit has been tested with dummy parameters and thereafter integrated with the actual test set up of hybrid DC circuit breaker. This paper deals with the conceptual design of the auto-triggering circuit, its control logic and operation. The test results of Hybrid DC circuit breaker using this circuit have also been discussed.

  1. Climate and environmental triggers of acute myocardial infarction.

    PubMed

    Claeys, Marc J; Rajagopalan, Sanjay; Nawrot, Tim S; Brook, Robert D

    2017-04-01

    Over the past few decades, a growing body of epidemiological and clinical evidence has led to heightened concerns about the potential short- and long-term deleterious effects of the environment on cardiovascular health, including the risk for acute myocardial infarction (AMI). This review highlights the increased risk of AMI caused by exposure to air pollution and cold temperatures. These factors should be considered modifiable risk factors in the prevention of cardiovascular disease. The current body of knowledge about the biological mechanisms linking environmental changes to atherothrombotic events and the impact of climate change on cardiovascular health are discussed. Finally, recommendations for prevention and public policy are presented. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2016. For permissions please email: journals.permissions@oup.com.

  2. Trigger Finger

    MedlinePlus

    ... in a bent position. People whose work or hobbies require repetitive gripping actions are at higher risk ... developing trigger finger include: Repeated gripping. Occupations and hobbies that involve repetitive hand use and prolonged gripping ...

  3. Individual and Environmental Factors Influencing Adolescents’ Dietary Behavior in Low- and Middle-Income Settings

    PubMed Central

    Verstraeten, Roosmarijn; Leroy, Jef L.; Pieniak, Zuzanna; Ochoa-Avilès, Angélica; Holdsworth, Michelle; Verbeke, Wim; Maes, Lea; Kolsteren, Patrick

    2016-01-01

    Objective Given the public health importance of improving dietary behavior in chronic disease prevention in low- and middle-income countries it is crucial to understand the factors influencing dietary behavior in these settings. This study tested the validity of a conceptual framework linking individual and environmental factors to dietary behavior among Ecuadorian adolescents aged 10–16 years. Methods A cross-sectional survey was conducted in 784 school-going Ecuadorian adolescents in urban and rural Southern Ecuador. Participants provided data on socio-economic status, anthropometry, dietary behavior and its determining factors. The relationships between individual (perceived benefits and barriers, self-efficacy, habit strength, and a better understanding of healthy food) and environmental factors (physical environment: accessibility to healthy food; social environment: parental permissiveness and school support), and their association with key components of dietary behavior (fruit and vegetables, sugary drinks, breakfast, and unhealthy snack intake) were assessed using structural equation modeling. Results The conceptual model performed well for each component of eating behavior, indicating acceptable goodness-of-fit for both the measurement and structural models. Models for vegetable intake and unhealthy snacking showed significant and direct effects of individual factors (perceived benefits). For breakfast and sugary drink consumption, there was a direct and positive association with socio-environmental factors (school support and parental permissiveness). Access to healthy food was associated indirectly with all eating behaviors (except for sugary drink intake) and this effect operated through socio-environmental (parental permissiveness and school support) and individual factors (perceived benefits). Conclusion Our study demonstrated that key components of adolescents’ dietary behaviors are influenced by a complex interplay of individual and

  4. Digital multispectral videography for the capture of environmental data sets.

    DOT National Transportation Integrated Search

    2000-08-01

    The Virginia Department of Transportation (VDOT) Environmental Division frequently uses spatial information to analyze and assess a variety of environmental resources. Environmental personnel are constantly looking for faster and more accurate means ...

  5. Acute sensory responses of nonsmokers at very low environmental tobacco smoke concentrations in controlled laboratory settings.

    PubMed

    Junker, M H; Danuser, B; Monn, C; Koller, T

    2001-10-01

    The objective of this study was to provide a basis for effectively protecting nonsmokers from acute sensory impacts and for preventing deterioration of indoor air quality caused by environmental tobacco smoke (ETS) emissions. With an olfactory experiment we determined odor detection thresholds (OT) of sidestream ETS (sETS), and with a full-body exposure experiment we investigated sensory symptoms at very low sETS exposure concentrations. OT concentrations for sETS are three and more orders of magnitude lower than ETS concentrations measured in field settings and correspond to a fresh air dilution volume of > 19,000 m(3) per cigarette, over 100 times more than had previously been suggested for acceptable indoor air conditions. Eye and nasal irritations were observed at one order of magnitude lower sETS concentrations than previously reported, corresponding to a fresh air dilution volume of > 3,000 m(3) per cigarette. These findings have great practical implications for defining indoor air quality standards in indoor compartments where ETS emissions occur. Our study strongly supports the implementation and control of smoking policies such as segregating smoking areas from areas where smoking is not permitted or instituting smoking bans in public buildings.

  6. Using earthquake-triggered landslides as a hillslope-scale shear strength test: Insights into rock strength properties at geomorphically relevant spatial scales in high-relief, tectonically active settings

    NASA Astrophysics Data System (ADS)

    Gallen, Sean; Clark, Marin; Godt, Jonathan; Lowe, Katherine

    2016-04-01

    The material strength of rock is known to be a fundamental property in setting landscape form and geomorphic process rates as it acts to modulate feedbacks between earth surface processes, tectonics, and climate. Despite the long recognition of its importance in landscape evolution, a quantitative understanding of the role of rock strength in affecting geomorphic processes lags our knowledge of the influence of tectonics and climate. This gap stems largely from the fact that it remains challenging to quantify rock strength at the hillslope scale. Rock strength is strongly scale dependent because the number, size, spacing, and aperture of fractures sets the upper limit on rock strength, making it difficult to extrapolate laboratory measurements to landscape-scale interpretations. Here we present a method to determine near-surface rock strength at the hillslope-scale, relying on earthquake-triggered landslides as a regional-scale "shear strength" test. We define near-surface strength as the average strength of rock sample by the landslides, which is typically < 10 m. Based on a Newmark sliding block model, which approximates slope stability during an earthquake assuming a material with frictional and cohesive strength, we developed a coseismic landslide model that is capable of reproducing statistical characteristics of the distribution of earthquake-triggered landslides. We present results from two well-documented case-studies of earthquakes that caused widespread mass-wasting; the 2008 Mw 7.9 Wenchuan Earthquake, Sichuan Province, China and the 1994 Mw. 6.8 Northridge Earthquake, CA, USA. We show how this model can be used to determine near-surface rock strength and reproduce mapped landslide patterns provided the spatial distribution of local hillslope gradient, earthquake peak ground acceleration (PGA), and coseismic landsliding are well constrained. Results suggest that near-surface rock strength in these tectonically active settings is much lower than that

  7. Radio AGN in the local universe: unification, triggering and evolution

    NASA Astrophysics Data System (ADS)

    Tadhunter, Clive

    2016-06-01

    Associated with one of the most important forms of active galactic nucleus (AGN) feedback, and showing a strong preference for giant elliptical host galaxies, radio AGN (L_{1.4 GHz} > 10^{24} W Hz^{-1}) are a key sub-class of the overall AGN population. Recently their study has benefitted dramatically from the availability of high-quality data covering the X-ray to far-IR wavelength range obtained with the current generation of ground- and space-based telescope facilities. Reflecting this progress, here I review our current state of understanding of the population of radio AGN at low and intermediate redshifts (z < 0.7), concentrating on their nuclear AGN and host galaxy properties, and covering three interlocking themes: the classification of radio AGN and its interpretation; the triggering and fuelling of the jet and AGN activity; and the evolution of the host galaxies. I show that much of the observed diversity in the AGN properties of radio AGN can be explained in terms of a combination of orientation/anisotropy, mass accretion rate, and variability effects. The detailed morphologies of the host galaxies are consistent with the triggering of strong-line radio galaxies (SLRG) in galaxy mergers. However, the star formation properties and cool ISM contents suggest that the triggering mergers are relatively minor in terms of their gas masses in most cases, and would not lead to major growth of the supermassive black holes and stellar bulges; therefore, apart from a minority (<20 %) that show evidence for higher star formation rates and more massive cool ISM reservoirs, the SLRG represent late-time re-triggering of activity in mature giant elliptical galaxies. In contrast, the host and environmental properties of weak-line radio galaxies (WLRG) with Fanaroff-Riley class I radio morphologies are consistent with more gradual fuelling of the activity via gas accretion at low rates onto the supermassive black holes.

  8. Risk analysis for dry snow slab avalanche release by skier triggering

    NASA Astrophysics Data System (ADS)

    McClung, David

    2013-04-01

    Risk analysis is of primary importance for skier triggering of avalanches since human triggering is responsible for about 90% of deaths from slab avalanches in Europe and North America. Two key measureable quantities about dry slab avalanche release prior to initiation are the depth to the weak layer and the slope angle. Both are important in risk analysis. As the slope angle increases, the probability of avalanche release increases dramatically. As the slab depth increases, the consequences increase if an avalanche releases. Among the simplest risk definitions is (Vick, 2002): Risk = (Probability of failure) x (Consequences of failure). Here, these two components of risk are the probability or chance of avalanche release and the consequences given avalanche release. In this paper, for the first time, skier triggered avalanches were analyzed from probability theory and its relation to risk for both the D and . The data consisted of two quantities : (,D) taken from avalanche fracture line profiles after an avalanche has taken place. Two data sets from accidentally skier triggered avalanches were considered: (1) 718 for and (2) a set of 1242 values of D which represent average values along the fracture line. The values of D were both estimated (about 2/3) and measured (about 1/3) by ski guides from Canadian Mountain Holidays CMH). I also analyzed 1231 accidentally skier triggered avalanches reported by CMH ski guides for avalanche size (representing destructive potential) on the Canadian scale. The size analysis provided a second analysis of consequences to verify that using D. The results showed that there is an intermediate range of both D and with highest risk. ForD, the risk (product of consequences and probability of occurrence) is highest for D in the approximate range 0.6 m - 1.0 m. The consequences are low for lower values of D and the chance of release is low for higher values of D. Thus, the highest product is in the intermediate range. For slope angles

  9. Activation of context-specific attentional control sets by exogenous allocation of visual attention to the context?

    PubMed

    Gottschalk, Caroline; Fischer, Rico

    2017-03-01

    Different contexts with high versus low conflict frequencies require a specific attentional control involvement, i.e., strong attentional control for high conflict contexts and less attentional control for low conflict contexts. While it is assumed that the corresponding control set can be activated upon stimulus presentation at the respective context (e.g., upper versus lower location), the actual features that trigger control set activation are to date not described. Here, we ask whether the perceptual priming of the location context by an abrupt onset of irrelevant stimuli is sufficient in activating the context-specific attentional control set. For example, the mere onset of a stimulus might disambiguate the relevant location context and thus, serve as a low-level perceptual trigger mechanism that activates the context-specific attentional control set. In Experiment 1 and 2, the onsets of task-relevant and task-irrelevant (distracter) stimuli were manipulated at each context location to compete for triggering the activation of the appropriate control set. In Experiment 3, a prior training session enabled distracter stimuli to establish contextual control associations of their own before entering the test session. Results consistently showed that the mere onset of a task-irrelevant stimulus (with or without a context-control association) is not sufficient to activate the context-associated attentional control set by disambiguating the relevant context location. Instead, we argue that the identification of the relevant stimulus at the respective context is a precondition to trigger the activation of the context-associated attentional control set.

  10. Environmental triggers of Past Ebola Outbreaks in Africa, 1981 - 2014

    NASA Astrophysics Data System (ADS)

    Dartevelle, S.; NguyRobertson, A. L.

    2016-12-01

    Ebola virus, especially its most common and lethal form, Zaire Ebolavirus, has eluded scientists nearly 50 years. What is its primary host? Why does it go dormant to suddenly to reappear full force years later? What are the driving forces behind its intriguing dynamic? It has been surmised that local environmental factors (such as droughts, seasons) might be at play behind the on-and-off Ebola outbreak outbursts. However, so far, no clear lead has been demonstrated making Ebola a constant hidden lethal menace lurking in the environment for many African communities. We have analyzed long-term time-series of three environmental variables that influence the controlling factor behind the cycle of Ebola virus outbreaks: (i) vegetation health, as determined from the Normalized Difference Vegetation Index (NDVI) collected by AVHRR and MODIS satellite sensors, and the weather variables (ii) temperature and (iii) precipitation from the Climate Forecast System ver. 2. Time series data were averaged monthly and spatially over a 100 km grid around past known outbreak locations. Seasonal effects were removed from these time series before applying statistical analyses identifying causal linkages between NDVI, temperature, precipitation and Ebola outbreaks. Likewise, possible tipping-points prior to outbreaks (i.e., early warning signals of an upcoming outbreak) were identified. Our results indicate that there is a causal dynamic link between outbreaks and the three environmental variables examined months prior to an outbreak. This was likely due to an abnormal change in the local precipitation pattern which influence NDVI values and to a lesser extent temperature. Furthermore, our results provide evidence that these factors demonstrate early warning signals of a dynamical system at a tipping-point, prior to a future outbreak. These tipping-point or early warning models may open new ways to furthermore develop forecast models of future Ebola outbreaks. [US Government — Approved

  11. Triggered tremor sweet spots in Alaska

    NASA Astrophysics Data System (ADS)

    Gomberg, Joan; Prejean, Stephanie

    2013-12-01

    To better understand what controls fault slip along plate boundaries, we have exploited the abundance of seismic and geodetic data available from the richly varied tectonic environments composing Alaska. A search for tremor triggered by 11 large earthquakes throughout all of seismically monitored Alaska reveals two tremor "sweet spots"—regions where large-amplitude seismic waves repeatedly triggered tremor between 2006 and 2012. The two sweet spots locate in very different tectonic environments—one just trenchward and between the Aleutian islands of Unalaska and Akutan and the other in central mainland Alaska. The Unalaska/Akutan spot corroborates previous evidence that the region is ripe for tremor, perhaps because it is located where plate-interface frictional properties transition between stick-slip and stably sliding in both the dip direction and laterally. The mainland sweet spot coincides with a region of complex and uncertain plate interactions, and where no slow slip events or major crustal faults have been noted previously. Analyses showed that larger triggering wave amplitudes, and perhaps lower frequencies (< 0.03 Hz), may enhance the probability of triggering tremor. However, neither the maximum amplitude in the time domain or in a particular frequency band, nor the geometric relationship of the wavefield to the tremor source faults alone ensures a high probability of triggering. Triggered tremor at the two sweet spots also does not occur during slow slip events visually detectable in GPS data, although slow slip below the detection threshold may have facilitated tremor triggering.

  12. Triggered tremor sweet spots in Alaska

    USGS Publications Warehouse

    Gomberg, Joan; Prejean, Stephanie

    2013-01-01

    To better understand what controls fault slip along plate boundaries, we have exploited the abundance of seismic and geodetic data available from the richly varied tectonic environments composing Alaska. A search for tremor triggered by 11 large earthquakes throughout all of seismically monitored Alaska reveals two tremor “sweet spots”—regions where large-amplitude seismic waves repeatedly triggered tremor between 2006 and 2012. The two sweet spots locate in very different tectonic environments—one just trenchward and between the Aleutian islands of Unalaska and Akutan and the other in central mainland Alaska. The Unalaska/Akutan spot corroborates previous evidence that the region is ripe for tremor, perhaps because it is located where plate-interface frictional properties transition between stick-slip and stably sliding in both the dip direction and laterally. The mainland sweet spot coincides with a region of complex and uncertain plate interactions, and where no slow slip events or major crustal faults have been noted previously. Analyses showed that larger triggering wave amplitudes, and perhaps lower frequencies (<~0.03 Hz), may enhance the probability of triggering tremor. However, neither the maximum amplitude in the time domain or in a particular frequency band, nor the geometric relationship of the wavefield to the tremor source faults alone ensures a high probability of triggering. Triggered tremor at the two sweet spots also does not occur during slow slip events visually detectable in GPS data, although slow slip below the detection threshold may have facilitated tremor triggering.

  13. The ATLAS high level trigger steering

    NASA Astrophysics Data System (ADS)

    Berger, N.; Bold, T.; Eifert, T.; Fischer, G.; George, S.; Haller, J.; Hoecker, A.; Masik, J.; Nedden, M. Z.; Reale, V. P.; Risler, C.; Schiavi, C.; Stelzer, J.; Wu, X.

    2008-07-01

    The High Level Trigger (HLT) of the ATLAS experiment at the Large Hadron Collider receives events which pass the LVL1 trigger at ~75 kHz and has to reduce the rate to ~200 Hz while retaining the most interesting physics. It is a software trigger and performs the reduction in two stages: the LVL2 trigger and the Event Filter (EF). At the heart of the HLT is the Steering software. To minimise processing time and data transfers it implements the novel event selection strategies of seeded, step-wise reconstruction and early rejection. The HLT is seeded by regions of interest identified at LVL1. These and the static configuration determine which algorithms are run to reconstruct event data and test the validity of trigger signatures. The decision to reject the event or continue is based on the valid signatures, taking into account pre-scale and pass-through. After the EF, event classification tags are assigned for streaming purposes. Several new features for commissioning and operation have been added: comprehensive monitoring is now built in to the framework; for validation and debugging, reconstructed data can be written out; the steering is integrated with the new configuration (presented separately), and topological and global triggers have been added. This paper will present details of the final design and its implementation, the principles behind it, and the requirements and constraints it is subject to. The experience gained from technical runs with realistic trigger menus will be described.

  14. The Sensorial Effect: Dynamics of Emotion in Pro-Environmental Behavior

    ERIC Educational Resources Information Center

    Hipolito, Joana

    2011-01-01

    In this article, sensorial effects are introduced as emotional stimuli for shaping environmentally significant behaviors. This research provides a link between sensorial effect as ubiquitous environmental behavior feedback and the effect of sensorial stimuli on emotions that trigger individuals' pro-environment behavior. A case study of using…

  15. Global Search of Triggered Tectonic Tremor

    NASA Astrophysics Data System (ADS)

    Peng, Z.; Aiken, C.; Chao, K.; Gonzalez-Huizar, H.; Wang, B.; Ojha, L.; Yang, H.

    2013-05-01

    Deep tectonic tremor has been observed at major plate-boundary faults around the Pacific Rim. While regular or ambient tremor occurs spontaneously or accompanies slow-slip events, tremor could be also triggered by large distant earthquakes and solid earth tides. Because triggered tremor occurs on the same fault patches as ambient tremor and is relatively easy to identify, a systematic global search of triggered tremor could help to identify the physical mechanisms and necessary conditions for tremor generation. Here we conduct a global search of tremor triggered by large teleseismic earthquakes. We mainly focus on major faults with significant strain accumulations where no tremor has been reported before. These includes subduction zones in Central and South America, strike-slip faults around the Caribbean plate, the Queen Charlotte-Fairweather fault system and the Denali fault in the western Canada and Alaska, the Sumatra-Java subduction zone, the Himalaya frontal thrust faults, as well as major strike-slip faults around Tibet. In each region, we first compute the predicted dynamic stresses σd from global earthquakes with magnitude>=5.0 in the past 20 years, and select events with σd > 1 kPa. Next, we download seismic data recorded by stations from local or global seismic networks, and identify triggered tremor as a high-frequency non-impulsive signal that is in phase with the large-amplitude teleseismic waves. In cases where station distributions are dense enough, we also locate tremor based on the standard envelope cross-correlation techniques. Finally, we calculate the triggering potential for the Love and Rayleigh waves with the local fault orientation and surface-wave incident angles. So far we have found several new places that are capable of generating triggered tremor. We will summarize these observations and discuss their implications on physical mechanisms of tremor and remote triggering.

  16. Tremor, remote triggering and earthquake cycle

    NASA Astrophysics Data System (ADS)

    Peng, Z.

    2012-12-01

    Deep tectonic tremor and episodic slow-slip events have been observed at major plate-boundary faults around the Pacific Rim. These events have much longer source durations than regular earthquakes, and are generally located near or below the seismogenic zone where regular earthquakes occur. Tremor and slow-slip events appear to be extremely stress sensitive, and could be instantaneously triggered by distant earthquakes and solid earth tides. However, many important questions remain open. For example, it is still not clear what are the necessary conditions for tremor generation, and how remote triggering could affect large earthquake cycle. Here I report a global search of tremor triggered by recent large teleseismic earthquakes. We mainly focus on major subduction zones around the Pacific Rim. These include the southwest and northeast Japan subduction zones, the Hikurangi subduction zone in New Zealand, the Cascadia subduction zone, and the major subduction zones in Central and South America. In addition, we examine major strike-slip faults around the Caribbean plate, the Queen Charlotte fault in northern Pacific Northwest Coast, and the San Andreas fault system in California. In each place, we first identify triggered tremor as a high-frequency non-impulsive signal that is in phase with the large-amplitude teleseismic waves. We also calculate the dynamic stress and check the triggering relationship with the Love and Rayleigh waves. Finally, we calculate the triggering potential with the local fault orientation and surface-wave incident angles. Our results suggest that tremor exists at many plate-boundary faults in different tectonic environments, and could be triggered by dynamic stress as low as a few kPas. In addition, we summarize recent observations of slow-slip events and earthquake swarms triggered by large distant earthquakes. Finally, we propose several mechanisms that could explain apparent clustering of large earthquakes around the world.

  17. Convergent and Divergent Signaling in PAMP-Triggered Immunity and Effector-Triggered Immunity.

    PubMed

    Peng, Yujun; van Wersch, Rowan; Zhang, Yuelin

    2018-04-01

    Plants use diverse immune receptors to sense pathogen attacks. Recognition of pathogen-associated molecular patterns (PAMPs) by pattern recognition receptors localized on the plasma membrane leads to PAMP-triggered immunity (PTI). Detection of pathogen effectors by intracellular or plasma membrane-localized immune receptors results in effector-triggered immunity (ETI). Despite the large variations in the magnitude and duration of immune responses triggered by different PAMPs or pathogen effectors during PTI and ETI, plasma membrane-localized immune receptors activate similar downstream molecular events such as mitogen-activated protein kinase activation, oxidative burst, ion influx, and increased biosynthesis of plant defense hormones, indicating that defense signals initiated at the plasma membrane converge at later points. On the other hand, activation of ETI by immune receptors localized to the nucleus appears to be more directly associated with transcriptional regulation of defense gene expression. Here, we review recent progress in signal transductions downstream of different groups of plant immune receptors, highlighting the converging and diverging molecular events.

  18. Electric field-triggered metal-insulator transition resistive switching of bilayered multiphasic VOx

    NASA Astrophysics Data System (ADS)

    Won, Seokjae; Lee, Sang Yeon; Hwang, Jungyeon; Park, Jucheol; Seo, Hyungtak

    2018-01-01

    Electric field-triggered Mott transition of VO2 for next-generation memory devices with sharp and fast resistance-switching response is considered to be ideal but the formation of single-phase VO2 by common deposition techniques is very challenging. Here, VOx films with a VO2-dominant phase for a Mott transition-based metal-insulator transition (MIT) switching device were successfully fabricated by the combined process of RF magnetron sputtering of V metal and subsequent O2 annealing to form. By performing various material characterizations, including scanning transmission electron microscopy-electron energy loss spectroscopy, the film is determined to have a bilayer structure consisting of a VO2-rich bottom layer acting as the Mott transition switching layer and a V2O5/V2O3 mixed top layer acting as a control layer that suppresses any stray leakage current and improves cyclic performance. This bilayer structure enables excellent electric field-triggered Mott transition-based resistive switching of Pt-VOx-Pt metal-insulator-metal devices with a set/reset current ratio reaching 200, set/reset voltage of less than 2.5 V, and very stable DC cyclic switching upto 120 cycles with a great set/reset current and voltage distribution less than 5% of standard deviation at room temperature, which are specifications applicable for neuromorphic or memory device applications. [Figure not available: see fulltext.

  19. Remote Triggering of Microseismicity in Antarctica

    NASA Astrophysics Data System (ADS)

    Ji, M.; Li, C.; Peng, Z.; Walter, J. I.

    2017-12-01

    It is well known that large distant earthquakes can trigger microearthquakes/tectonic tremors during or immediately following their surface waves. Globally, triggered seismicity is mostly found in active plate boundary regions. Recent studies have shown that icequakes in Antartica can also be triggered by teleseismic events. However, it is still not clear how widespread this phenomenon is and whether there are any connections between large earthquakes and subsequent glacial movements. In this study, we conduct a systematic search for remotely triggered activity in Antarctica following recent large earthquakes, including the 2004 Mw9.1 Sumatra, 2011 Mw9.1 Tohoku, 2012 Mw8.6 Indian Ocean and 2014-2015 Chile earthquakes. We download seismic data recorded at the POLENET (YT) and the Argentina Antarctica Network (AI) from the Incorporated Research Institutions for Seismology (IRIS) Data Management Center (DMC). We apply a 2-8 Hz band-pass-filter to the continuous waveforms and visually identify local events during and immediately after the large amplitude surface waves. Spectrograms are computed as additional tools to identify triggered seismicity and are further confirmed by comparing the signals before and after the distant mainshocks. So far we have identified possible triggered seismicity in both networks' area following the 2010 Chile and 2011 Tohoku earthquakes. Our next step is to apply a waveform matching method to automatically detect possible triggered seismicity and check through all the available networks in Antarctica for the last decades, which should help to better understand the potential interaction between large earthquakes and icequakes in this region.

  20. Triggering active galactic nuclei in galaxy clusters

    NASA Astrophysics Data System (ADS)

    Marshall, Madeline A.; Shabala, Stanislav S.; Krause, Martin G. H.; Pimbblet, Kevin A.; Croton, Darren J.; Owers, Matt S.

    2018-03-01

    We model the triggering of active galactic nuclei (AGN) in galaxy clusters using the semi-analytic galaxy formation model SAGE. We prescribe triggering methods based on the ram pressure galaxies experience as they move throughout the intracluster medium, which is hypothesized to trigger star formation and AGN activity. The clustercentric radius and velocity distribution of the simulated active galaxies produced by these models are compared with those of AGN and galaxies with intense star formation from a sample of low-redshift relaxed clusters from the Sloan Digital Sky Survey. The ram pressure triggering model that best explains the clustercentric radius and velocity distribution of these observed galaxies has AGN and star formation triggered if 2.5 × 10-14 Pa < Pram < 2.5 × 10-13 Pa and Pram > 2Pinternal; this is consistent with expectations from hydrodynamical simulations of ram-pressure-induced star formation. Our results show that ram pressure is likely to be an important mechanism for triggering star formation and AGN activity in clusters.

  1. Water-quality assessment of the lower Illinois River Basin; environmental setting

    USGS Publications Warehouse

    Warner, Kelly L.

    1998-01-01

    The lower Illinois River Basin (LIRB) encompasses 18,000 square miles of central and western Illinois. Historical and recent information from Federal, State, and local agencies describing the physiography, population, land use, soils, climate, geology, streamflow, habitat, ground water, water use, and aquatic biology is summarized to describe the environmental setting of the LIRB. The LIRB is in the Till Plains Section of the Central Lowland physiographic province. The basin is characterized by flat topography, which is dissected by the Illinois River. The drainage pattern of the LIRB has been shaped by many bedrock and glacial geologic processes. Erosion prior to and during Pleistocene time created wide and deep bedrock valleys. The thickest deposits and most major aquifers are in buried bedrock valleys. The Wisconsinan glaciation, which bisects the northern half of the LIRB, affects the distribution and characteristics of glacial deposits in the basin. Agriculture is the largest land use and forested land is the second largest land use in the LIRB. The major urban areas are near Peoria, Springfield, Decatur, and Bloomington-Normal. Soil type and distribution affect the amount of soil erosion, which results in sedimentation of lakes and reservoirs in the basin. Rates of soil erosion of up to 2 percent per year of farmland soil have been measured. Many of the 300 reservoirs, lakes, and wetlands are disappearing because of sedimentation resulting from agriculture activities, levee building, and urbanization. Sedimentation and the destruction of habitat appreciably affect the ecosystem. The Illinois River is a large river-floodplain ecosystem where biological productivity is enhanced by annual flood pulses that advance and retreat over the flood plain and temporarily expand backwater and flood-plain lakes. Ground-water discharge to streams affects the flow and water quality of the streams. The water budget of several subbasins show variability in ground

  2. Transient triggering of near and distant earthquakes

    USGS Publications Warehouse

    Gomberg, J.; Blanpied, M.L.; Beeler, N.M.

    1997-01-01

    We demonstrate qualitatively that frictional instability theory provides a context for understanding how earthquakes may be triggered by transient loads associated with seismic waves from near and distance earthquakes. We assume that earthquake triggering is a stick-slip process and test two hypotheses about the effect of transients on the timing of instabilities using a simple spring-slider model and a rate- and state-dependent friction constitutive law. A critical triggering threshold is implicit in such a model formulation. Our first hypothesis is that transient loads lead to clock advances; i.e., transients hasten the time of earthquakes that would have happened eventually due to constant background loading alone. Modeling results demonstrate that transient loads do lead to clock advances and that the triggered instabilities may occur after the transient has ceased (i.e., triggering may be delayed). These simple "clock-advance" models predict complex relationships between the triggering delay, the clock advance, and the transient characteristics. The triggering delay and the degree of clock advance both depend nonlinearly on when in the earthquake cycle the transient load is applied. This implies that the stress required to bring about failure does not depend linearly on loading time, even when the fault is loaded at a constant rate. The timing of instability also depends nonlinearly on the transient loading rate, faster rates more rapidly hastening instability. This implies that higher-frequency and/or longer-duration seismic waves should increase the amount of clock advance. These modeling results and simple calculations suggest that near (tens of kilometers) small/moderate earthquakes and remote (thousands of kilometers) earthquakes with magnitudes 2 to 3 units larger may be equally effective at triggering seismicity. Our second hypothesis is that some triggered seismicity represents earthquakes that would not have happened without the transient load (i

  3. New study shows normally helpful natural bacteria may also trigger lupus | Center for Cancer Research

    Cancer.gov

    CCR scientists have discovered that a protein produced by bacteria that naturally inhabit our bodies may trigger the autoimmune disease lupus. The results of the study could unveil an entirely new set of drug targets for treating lupus and other autoimmune diseases. Read more…

  4. A novel in situ trigger combination method

    DOE PAGES

    Buzatu, Adrian; Warburton, Andreas; Krumnack, Nils; ...

    2013-01-30

    Searches for rare physics processes using particle detectors in high-luminosity colliding hadronic beam environments require the use of multi-level trigger systems to reject colossal background rates in real time. In analyses like the search for the Higgs boson, there is a need to maximize the signal acceptance by combining multiple different trigger chains when forming the offline data sample. In such statistically limited searches, datasets are often amassed over periods of several years, during which the trigger characteristics evolve and system performance can vary significantly. Reliable production cross-section measurements and upper limits must take into account a detailed understanding ofmore » the effective trigger inefficiency for every selected candidate event. We present as an example the complex situation of three trigger chains, based on missing energy and jet energy, that were combined in the context of the search for the Higgs (H) boson produced in association with a $W$ boson at the Collider Detector at Fermilab (CDF). We briefly review the existing techniques for combining triggers, namely the inclusion, division, and exclusion methods. We introduce and describe a novel fourth in situ method whereby, for each candidate event, only the trigger chain with the highest a priori probability of selecting the event is considered. We compare the inclusion and novel in situ methods for signal event yields in the CDF $WH$ search. This new combination method, by virtue of its scalability to large numbers of differing trigger chains and insensitivity to correlations between triggers, will benefit future long-running collider experiments, including those currently operating on the Large Hadron Collider.« less

  5. A novel in situ trigger combination method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Buzatu, Adrian; Warburton, Andreas; Krumnack, Nils

    Searches for rare physics processes using particle detectors in high-luminosity colliding hadronic beam environments require the use of multi-level trigger systems to reject colossal background rates in real time. In analyses like the search for the Higgs boson, there is a need to maximize the signal acceptance by combining multiple different trigger chains when forming the offline data sample. In such statistically limited searches, datasets are often amassed over periods of several years, during which the trigger characteristics evolve and system performance can vary significantly. Reliable production cross-section measurements and upper limits must take into account a detailed understanding ofmore » the effective trigger inefficiency for every selected candidate event. We present as an example the complex situation of three trigger chains, based on missing energy and jet energy, that were combined in the context of the search for the Higgs (H) boson produced in association with a $W$ boson at the Collider Detector at Fermilab (CDF). We briefly review the existing techniques for combining triggers, namely the inclusion, division, and exclusion methods. We introduce and describe a novel fourth in situ method whereby, for each candidate event, only the trigger chain with the highest a priori probability of selecting the event is considered. We compare the inclusion and novel in situ methods for signal event yields in the CDF $WH$ search. This new combination method, by virtue of its scalability to large numbers of differing trigger chains and insensitivity to correlations between triggers, will benefit future long-running collider experiments, including those currently operating on the Large Hadron Collider.« less

  6. Graphical processors for HEP trigger systems

    NASA Astrophysics Data System (ADS)

    Ammendola, R.; Biagioni, A.; Chiozzi, S.; Cotta Ramusino, A.; Di Lorenzo, S.; Fantechi, R.; Fiorini, M.; Frezza, O.; Lamanna, G.; Lo Cicero, F.; Lonardo, A.; Martinelli, M.; Neri, I.; Paolucci, P. S.; Pastorelli, E.; Piandani, R.; Pontisso, L.; Rossetti, D.; Simula, F.; Sozzi, M.; Vicini, P.

    2017-02-01

    General-purpose computing on GPUs is emerging as a new paradigm in several fields of science, although so far applications have been tailored to employ GPUs as accelerators in offline computations. With the steady decrease of GPU latencies and the increase in link and memory throughputs, time is ripe for real-time applications using GPUs in high-energy physics data acquisition and trigger systems. We will discuss the use of online parallel computing on GPUs for synchronous low level trigger systems, focusing on tests performed on the trigger of the CERN NA62 experiment. Latencies of all components need analysing, networking being the most critical. To keep it under control, we envisioned NaNet, an FPGA-based PCIe Network Interface Card (NIC) enabling GPUDirect connection. Moreover, we discuss how specific trigger algorithms can be parallelised and thus benefit from a GPU implementation, in terms of increased execution speed. Such improvements are particularly relevant for the foreseen LHC luminosity upgrade where highly selective algorithms will be crucial to maintain sustainable trigger rates with very high pileup.

  7. Enterovirus infection--a possible trigger for Graves' disease?

    PubMed

    Pichler, R; Maschek, W; Hatzl-Griesenhofer, M; Huber, H; Luger, C; Binder, L; Mittermayer, H

    2001-03-15

    Viruses are potential environmental factors in autoimmune disease. Some evidence suggests a relationship between enteroviral infection (especially Coxsackie B virus) and autoimmunity. We investigated 21 individuals with recent onset of Graves' hyperthyroidism in regard of (subclinical) enterovirus infection. Thyrotoxic symptoms had started about two months before blood sample collection. The patients were from Upper Austria and mainly female (17/21). Their mean free thyroxin levels in blood were twice the maximum normal value and the majority achieved a euthyroid state 1 1/2 years later, after antithyroid medication. We employed a nested PCR reaction with primers of the enterovirus genome on blood samples. All were negative for RNA of the enterovirus group. Coxsackie and related viruses were not identified as a trigger factor in autoimmune thyrotoxic disease.

  8. Education Modifies Genetic and Environmental Influences on BMI

    PubMed Central

    Johnson, Wendy; Kyvik, Kirsten Ohm; Skytthe, Axel; Deary, Ian J.; Sørensen, Thorkild I. A.

    2011-01-01

    Obesity is more common among the less educated, suggesting education-related environmental triggers. Such triggers may act differently dependent on genetic and environmental predisposition to obesity. In a Danish Twin Registry survey, 21,522 twins of same-sex pairs provided zygosity, height, weight, and education data. Body mass index (BMI = kg weight/ m height2) was used to measure degree of obesity. We used quantitative genetic modeling to examine how genetic and shared and nonshared environmental variance in BMI differed by level of education and to estimate how genetic and shared and nonshared environmental correlations between education and BMI differed by level of education, analyzing women and men separately. Correlations between education and BMI were −.13 in women, −.15 in men. High BMI's were less frequent among well-educated participants, generating less variance. In women, this was due to restriction of all forms of variance, overall by a factor of about 2. In men, genetic variance did not vary with education, but results for shared and nonshared environmental variance were similar to those for women. The contributions of the shared environment to the correlations between education and BMI were substantial among the well-educated, suggesting importance of familial environmental influences common to high education and lower BMI. Family influence was particularly important in linking high education and lower levels of obesity. PMID:21283825

  9. A new function for estimating local rainfall thresholds for landslide triggering

    NASA Astrophysics Data System (ADS)

    Cepeda, J.; Nadim, F.; Høeg, K.; Elverhøi, A.

    2009-04-01

    The widely used power law for establishing rainfall thresholds for triggering of landslides was first proposed by N. Caine in 1980. The most updated global thresholds presented by F. Guzzetti and co-workers in 2008 were derived using Caine's power law and a rigorous and comprehensive collection of global data. Caine's function is defined as I = α×Dβ, where I and D are the mean intensity and total duration of rainfall, and α and β are parameters estimated for a lower boundary curve to most or all the positive observations (i.e., landslide triggering rainfall events). This function does not account for the effect of antecedent precipitation as a conditioning factor for slope instability, an approach that may be adequate for global or regional thresholds that include landslides in surface geologies with a wide range of subsurface drainage conditions and pore-pressure responses to sustained rainfall. However, in a local scale and in geological settings dominated by a narrow range of drainage conditions and behaviours of pore-pressure response, the inclusion of antecedent precipitation in the definition of thresholds becomes necessary in order to ensure their optimum performance, especially when used as part of early warning systems (i.e., false alarms and missed events must be kept to a minimum). Some authors have incorporated the effect of antecedent rainfall in a discrete manner by first comparing the accumulated precipitation during a specified number of days against a reference value and then using a Caine's function threshold only when that reference value is exceeded. The approach in other authors has been to calculate threshold values as linear combinations of several triggering and antecedent parameters. The present study is aimed to proposing a new threshold function based on a generalisation of Caine's power law. The proposed function has the form I = (α1×Anα2)×Dβ, where I and D are defined as previously. The expression in parentheses is

  10. Accounting for the social triggers of sexual compulsivity.

    PubMed

    Parsons, Jeffrey T; Kelly, Brian C; Bimbi, David S; Muench, Frederick; Morgenstern, Jon

    2007-01-01

    To examine the social triggers of sexual compulsivity amongst a diverse sample of gay and bisexual men. Qualitative interviews were conducted with 180 gay and bisexual men in the United States who self-identified that their sex lives were spinning out of control. The data were analyzed using a grounded theory approach to explore the range of social triggers that were driving sexual compulsions. An open-ended interview and a structured clinical interview were conducted with each participant. The interviews examined their experiences with sexual compulsivity over time and the impact of their problematic sexual behaviors on their lives. Two types of social triggers emerged from the data: event-centered triggers and contextual triggers. Event-centered triggers arise from sudden, unforeseen events. Two major event-centered triggers were identified: relationship turmoil and catastrophes. Contextual triggers, on the other hand, have a certain element of predictability, and included such things as location, people, the use of drugs, and pornography. This framework of triggers has clinical implications for the prevention and treatment of sexual compulsivity. Clinicians can utilize the framework of social triggers in the therapeutic process to provide insight into ways to effectively work through symptoms of sexual compulsivity. Awareness of the contextual aspects of sexual compulsivity may be critical to understanding the behaviors of sexually compulsive clients. Thus, therapeutic assessments should focus upon the social context in addition to the psychological components of the disorder.

  11. Asthma Education and Intervention Program: Partnership for Asthma Trigger-Free Homes (PATH)

    DTIC Science & Technology

    2008-08-01

    military setting if additional funding is procured.) 15. SUBJECT TERMS Asthma , longitudinal study, asthma education, indoor asthma triggers, dust...caregiver quality of life, we make use of the Juniper Pediatric Asthma Caregiver’s Quality of Life questionnaire (PACQLQ). It measures the problems that...whose reliability and validity are described below. We employ the Juniper Pediatric Asthma Caregiver’s Quality of Life questionnaire (PACQLQ) to measure

  12. Environmental settings of streams sampled for mercury in New York and South Carolina, 2005-09

    USGS Publications Warehouse

    Scudder Eikenberry, Barbara C.; Riva-Murray, Karen; Smith, Martyn J.; Bradley, Paul M.; Button, Daniel T.; Clark, Jimmy M.; Burns, Douglas A.; Journey, Celeste A.

    2011-01-01

    This report summarizes the environmental settings of streams in New York and South Carolina, where the U.S. Geological Survey completed detailed investigations during 2005-09 into factors contributing to mercury bioaccumulation in top-predator fish and other stream organisms. Descriptions of location, land use/land cover, climate, precipitation, atmospheric deposition, hydrology, water temperature, and other characteristics are provided. Atmospheric deposition is the dominant mercury source in the studied basins where biota, sediment, soil, and water were sampled for mercury and for physical and chemical characteristics believed to be important in mercury methylation and transport.

  13. "The World Is Our Home": Environmental Justice, Feminisms, and Student Ideology

    ERIC Educational Resources Information Center

    Plevin, Arlene

    2006-01-01

    From interacting with their students, many teachers are aware that the concepts of feminism and environmentalism can conjure up impoverished, deficient, and equally painful stereotypes. For some college students, feminism can mean merely equal pay for equal work. Environmentalism may trigger similarly limited associations, but inevitably…

  14. Long- and short-term triggering and modulation of mud volcano eruptions by earthquakes

    NASA Astrophysics Data System (ADS)

    Bonini, Marco; Rudolph, Maxwell L.; Manga, Michael

    2016-03-01

    Earthquakes can trigger the eruption of mud. We use eruptions in Azerbaijan, Italy, Romania, Japan, Andaman Islands, Pakistan, Taiwan, Indonesia, and California to probe the nature of stress changes that induce new eruptions and modulate ongoing eruptions. Dynamic stresses produced by earthquakes are usually inferred to be the dominant triggering mechanism; however static stress changes acting on the feeder systems of mud volcanoes may also play a role. In Azerbaijan, eruptions within 2-10 fault lengths from the epicenter are favored in the year following earthquakes where the static stress changes cause compression of the mud source and unclamp feeder dikes. In Romania, Taiwan, and some Italian sites, increased activity is also favored where the static stress changes act to unclamp feeder dikes, but responses occur within days. The eruption in the Andaman Islands, and those of the Niikappu mud volcanoes, Japan are better correlated with amplitude of dynamic stresses produced by seismic waves. Similarly, a new island that emerged off the coast of Pakistan in 2013 was likely triggered by dynamic stresses, enhanced by directivity. At the southern end of the Salton Sea, California earthquakes increase the gas flux at small mud volcanoes. Responses are best correlated with dynamic stresses. The comparison of responses in these nine settings indicates that dynamic stresses are most often correlated with triggering, although permanent stress changes as small as, and possibly smaller than, 0.1 bar may be sufficient to also influence eruptions. Unclamping stresses with magnitude similar to Earth tides (0.01 bar) persist over time and may play a role in triggering delayed responses. Unclamping stresses may be important contributors to short-term triggering only if they exceed 0.1-1 bar.

  15. More Than a Text Message: Dismantling Digital Triggers to Curate Behavior Change in Patient-Centered Health Interventions

    PubMed Central

    2017-01-01

    Digital triggers such as text messages, emails, and push alerts are designed to focus an individual on a desired goal by prompting an internal or external reaction at the appropriate time. Triggers therefore have an essential role in engaging individuals with digital interventions delivered outside of traditional health care settings, where other events in daily lives and fluctuating motivation to engage in effortful behavior exist. There is an emerging body of literature examining the use of digital triggers for short-term action and longer-term behavior change. However, little attention has been given to understanding the components of digital triggers. Using tailoring as an overarching framework, we separated digital triggers into 5 primary components: (1) who (sender), (2) how (stimulus type, delivery medium, heterogeneity), (3) when (delivered), (4) how much (frequency, intensity), and (5) what (trigger’s target, trigger’s structure, trigger’s narrative). We highlighted key considerations when tailoring each component and the pitfalls of ignoring common mistakes, such as alert fatigue and habituation. As evidenced throughout the paper, there is a broad literature base from which to draw when tailoring triggers to curate behavior change in health interventions. More research is needed, however, to examine differences in efficacy based on component tailoring, to best use triggers to facilitate behavior change over time, and to keep individuals engaged in physical and mental health behavior change efforts. Dismantling digital triggers into their component parts and reassembling them according to the gestalt of one’s change goals is the first step in this development work. PMID:28550001

  16. Robotically assisted velocity-sensitive triggered focused ultrasound surgery

    NASA Astrophysics Data System (ADS)

    Maier, Florian; Brunner, Alexander; Jenne, Jürgen W.; Krafft, Axel J.; Semmler, Wolfhard; Bock, Michael

    2012-11-01

    Magnetic Resonance (MR) guided Focused Ultrasound Surgery (FUS) of abdominal organs is challenging due to breathing motion and limited patient access in the MR environment. In this work, an experimental robotically assisted FUS setup was combined with a MR-based navigator technique to realize motion-compensated sonications and online temperature imaging. Experiments were carried out in a static phantom, during periodic manual motion of the phantom without triggering, and with triggering to evaluate the triggering method. In contrast to the non-triggered sonication, the results of the triggered sonication show a confined symmetric temperature distribution. In conclusion, the velocity sensitive navigator can be employed for triggered FUS to compensate for periodic motion. Combined with the robotic FUS setup, flexible treatment of abdominal targets might be realized.

  17. Application of quality risk management to set viable environmental monitoring frequencies in biotechnology processing and support areas.

    PubMed

    Sandle, Tim

    2012-01-01

    Environmental monitoring programs are essential for pharmaceutical facilities in order to assess the level of environmental control. For biotechnology facilities there is little advice as to the frequency at which viable environmental monitoring should be conducted. This paper outlines an approach, based on the principles of quality risk management, for the development of a framework from which monitoring frequencies can be determined. This involved the identification of common hazards and the evaluation those hazards in terms of the severity of contamination and the probability of contamination occurring. These elements of risk were evaluated for different cleanrooms and the relative risks ranked. Once the risk scores were calculated, the methods for detecting risks within the cleanrooms were assessed. Risk filtering was then used to group different cleanrooms based on their relative risks and detection methods against predetermined monitoring frequencies. Through use of case study examples, the paper presents the model and describes how appropriate frequencies for the environmental monitoring of cleanrooms can be set. Cleanrooms in which biotechnology pharmaceutical processing takes place are subject to environmental monitoring. The frequency at which such monitoring should be performed can be difficult to determine. This paper uses quality risk assessment methods to construct a framework for determining monitoring frequencies and illustrates the suitability of the framework through a case study.

  18. Eco-innovation of a wooden childhood furniture set: an example of environmental solutions in the wood sector.

    PubMed

    González-García, Sara; García Lozano, Raúl; Moreira, M Teresa; Gabarrell, Xavier; Rieradevall i Pons, Joan; Feijoo, Gumersindo; Murphy, Richard J

    2012-06-01

    The environmental profile of a set of wood furniture was carried out to define the best design criteria for its eco-design. A baby cot convertible into a bed, a study desk and a bedside table were the objects of study. Two quantitative and qualitative environmental approaches were combined in order to propose improvement alternatives: Life Cycle Assessment (LCA) and Design for Environment (DfE). In the first case Life Cycle Assessment (LCA) was applied to identify the hot spots in the product system. As a next step, LCA information was used in eco-briefing to determine several improvement alternatives. A wood products company located in Catalonia (NE Spain) was assessed in detail, dividing the process into three stages: assembly, finishing and packaging. Ten impact categories were considered in the LCA study: abiotic depletion, acidification, eutrophication, global warming, ozone layer depletion, human toxicity, fresh water aquatic ecotoxicity, marine aquatic ecotoxicity, terrestrial ecotoxicity and photochemical oxidant formation. Two processes can be considered the key environmental factors: the production of the wooden boards and electricity, with contributions of 45-68% and 14-33% respectively depending on the impact categories. Subsequently, several improvement alternatives were proposed in the eco-design process (DfE) to achieve reductions in a short-medium period of time in the environmental impact. These eco-design strategies could reduce the environmental profile of the setup by 14%. The correct methodological adaptation of the concept of eco-briefing, as a tool for communication among environmental technicians and designers, the simplification of the analytical tool used and the LCA, could facilitate the environmental analysis of a product. The results obtained provide information that can help the furniture sector to improve their environmental performance. Copyright © 2012 Elsevier B.V. All rights reserved.

  19. Emotional triggers in myocardial infarction: do they matter?

    PubMed

    Edmondson, Donald; Newman, Jonathan D; Whang, William; Davidson, Karina W

    2013-01-01

    Considerable excitement and interest have arisen recently concerning the role that acute emotional triggers may play in precipitating a myocardial infarction (MI). Observational studies have found repeatedly that patients report excessive anger, anxiety, sadness, grief, or acute stress immediately prior to onset of MI, and recent meta-analyses summarizing these findings reported strong associations between MI occurrence and many of these acute emotions. However, it is unclear whether and through what mechanisms acute emotional triggers might influence MI, and whether there is any clinical utility in knowing if or how emotions trigger MI. We debate whether emotional triggers matter by reviewing the recent evidence for the association between acute emotional triggers and MI and by describing the potential pathophysiological characteristics and mechanisms underlying this association and the preventive strategies that could be used to mitigate the risk of acute MI. We also examine whether the study of emotional triggers could influence clinical risk management or changes in clinical practice/management. We offer suggestions for research that might shed light on whether emotional triggers could initiate a paradigm shift in preventive cardiology, or whether acute emotional triggers are either intractable catalysts for, or merely an epiphenomenon of, some MIs.

  20. Creating accessible science museums with user-activated environmental audio beacons (ping!).

    PubMed

    Landau, Steven; Wiener, William; Naghshineh, Koorosh; Giusti, Ellen

    2005-01-01

    In 2003, Touch Graphics Company carried out research on a new invention that promises to improve accessibility to science museums for visitors who are visually impaired. The system, nicknamed Ping!, allows users to navigate an exhibit area, listen to audio descriptions, and interact with exhibits using a cell phone-based interface. The system relies on computer telephony, and it incorporates a network of wireless environmental audio beacons that can be triggered by users wishing to travel to destinations they choose. User testing indicates that the system is effective, both as a way-finding tool and as a means of providing accessible information on museum content. Follow-up development projects will determine if this approach can be successfully implemented in other settings and for other user populations.

  1. Environmental setting of benchmark streams in agricultural areas of eastern Wisconsin

    USGS Publications Warehouse

    Rheaume, S.J.; Stewart, J.S.; Lenz, B.N.

    1996-01-01

    Differences in land use/land cover, and riparian vegetation and instream habitat characteristics are presented. Summaries of field measurements of water temperature, pH, specific conductance and concentrations of dissolved oxygen, total organic plus ammonia nitrogen, dissolved ammonium, nitrate plus nitrte as nitrogen, total phosphorus, dissolved orthophosphate, and atrazine are listed. Concentrations of dissolved oxygen for the sampled streams ranged from 6 A to 14.3 and met the standards set by the Wisconsin Department of Natural Resources (WDNR) for supporting fish and aquatic life. Specific conductance ranged from 98 to 753 u,Scm with values highest in RHU's 1 and 3, where streams are underlain by carbonate bedrock. Median pH did not vary greatly among the four RHU's and ranged from 6.7 to 8.8 also meeting the WDNR standards. Concentrations of total organic plus ammonia nitrogen, dissolved ammonium, total phosphorus, and dissolved orthophosphate show little variation between streams and are generally low, compared to concentrations measured in agriculturally-affected streams in the same RHU's during the same sampling period. Concentrations of the most commonly used pesticide in the study unit, atrazine, were low in all streams, and most concentrations were below trn 0.1 u,g/L detection limit. Riparian vegetation for the benchmark streams were characterized by lowland species of the native plant communities described by John T. Curtis in the "Vegetation of Wisconsin." Based on the environmental setting and water-quality information collected to date, these streams appear to show minimal adverse effects from human activity.

  2. Physical activity and healthy eating environmental audit tools in youth care settings: A systematic review.

    PubMed

    Ajja, Rahma; Beets, Michael W; Chandler, Jessica; Kaczynski, Andrew T; Ward, Dianne S

    2015-08-01

    There is a growing interest in evaluating the physical activity (PA) and healthy eating (HE) policy and practice environment characteristics in settings frequented by youth (≤18years). This review evaluates the measurement properties of audit tools designed to assess PA and HE policy and practice environment characteristics in settings that care for youth (e.g., childcare, school, afterschool, summer camp). Three electronic databases, reference lists, educational department and national health organizations' web pages were searched between January 1980 and February 2014 to identify tools assessing PA and/or HE policy and practice environments in settings that care for youth (≤18years). Sixty-five audit tools were identified of which 53 individual tools met the inclusion criteria. Thirty-three tools assessed both the PA and HE domains, 6 assessed the PA domain and 14 assessed the HE domain solely. The majority of the tools were self-assessment tools (n=40), and were developed to assess the PA and/or HE environment in school settings (n=33), childcare (n=12), and after school programs (n=4). Four tools assessed the community at-large and had sections for assessing preschool, school and/or afterschool settings within the tool. The majority of audit tools lacked validity and/or reliability data (n=42). Inter-rater reliability and construct validity were the most frequently reported reliability (n=7) and validity types (n=5). Limited attention has been given to establishing the reliability and validity of audit tools for settings that care for youth. Future efforts should be directed towards establishing a strong measurement foundation for these important environmental audit tools. Published by Elsevier Inc.

  3. Emotional triggers in myocardial infarction: do they matter?

    PubMed Central

    Edmondson, Donald; Newman, Jonathan D.; Whang, William; Davidson, Karina W.

    2013-01-01

    Considerable excitement and interest have arisen recently concerning the role that acute emotional triggers may play in precipitating a myocardial infarction (MI). Observational studies have found repeatedly that patients report excessive anger, anxiety, sadness, grief, or acute stress immediately prior to onset of MI, and recent meta-analyses summarizing these findings reported strong associations between MI occurrence and many of these acute emotions. However, it is unclear whether and through what mechanisms acute emotional triggers might influence MI, and whether there is any clinical utility in knowing if or how emotions trigger MI. We debate whether emotional triggers matter by reviewing the recent evidence for the association between acute emotional triggers and MI and by describing the potential pathophysiological characteristics and mechanisms underlying this association and the preventive strategies that could be used to mitigate the risk of acute MI. We also examine whether the study of emotional triggers could influence clinical risk management or changes in clinical practice/management. We offer suggestions for research that might shed light on whether emotional triggers could initiate a paradigm shift in preventive cardiology, or whether acute emotional triggers are either intractable catalysts for, or merely an epiphenomenon of, some MIs. PMID:23178642

  4. Recognising discourse causality triggers in the biomedical domain.

    PubMed

    Mihăilă, Claudiu; Ananiadou, Sophia

    2013-12-01

    Current domain-specific information extraction systems represent an important resource for biomedical researchers, who need to process vast amounts of knowledge in a short time. Automatic discourse causality recognition can further reduce their workload by suggesting possible causal connections and aiding in the curation of pathway models. We describe here an approach to the automatic identification of discourse causality triggers in the biomedical domain using machine learning. We create several baselines and experiment with and compare various parameter settings for three algorithms, i.e. Conditional Random Fields (CRF), Support Vector Machines (SVM) and Random Forests (RF). We also evaluate the impact of lexical, syntactic, and semantic features on each of the algorithms, showing that semantics improves the performance in all cases. We test our comprehensive feature set on two corpora containing gold standard annotations of causal relations, and demonstrate the need for more gold standard data. The best performance of 79.35% F-score is achieved by CRFs when using all three feature types.

  5. Performance of the ATLAS Trigger System in 2010

    NASA Astrophysics Data System (ADS)

    Aad, G.; Abbott, B.; Abdallah, J.; Abdelalim, A. A.; Abdesselam, A.; Abdinov, O.; Abi, B.; Abolins, M.; Abramowicz, H.; Abreu, H.; Acerbi, E.; Acharya, B. S.; Adams, D. L.; Addy, T. N.; Adelman, J.; Aderholz, M.; Adomeit, S.; Adragna, P.; Adye, T.; Aefsky, S.; Aguilar-Saavedra, J. A.; Aharrouche, M.; Ahlen, S. P.; Ahles, F.; Ahmad, A.; Ahsan, M.; Aielli, G.; Akdogan, T.; Åkesson, T. P. A.; Akimoto, G.; Akimov, A. V.; Akiyama, A.; Alam, M. S.; Alam, M. A.; Albrand, S.; Aleksa, M.; Aleksandrov, I. N.; Alessandria, F.; Alexa, C.; Alexander, G.; Alexandre, G.; Alexopoulos, T.; Alhroob, M.; Aliev, M.; Alimonti, G.; Alison, J.; Aliyev, M.; Allport, P. P.; Allwood-Spiers, S. E.; Almond, J.; Aloisio, A.; Alon, R.; Alonso, A.; Alviggi, M. G.; Amako, K.; Amaral, P.; Amelung, C.; Ammosov, V. V.; Amorim, A.; Amorós, G.; Amram, N.; Anastopoulos, C.; Andari, N.; Andeen, T.; Anders, C. F.; Anderson, K. J.; Andreazza, A.; Andrei, V.; Andrieux, M.-L.; Anduaga, X. S.; Angerami, A.; Anghinolfi, F.; Anjos, N.; Annovi, A.; Antonaki, A.; Antonelli, M.; Antonelli, S.; Antonov, A.; Antos, J.; Anulli, F.; Aoun, S.; Aperio Bella, L.; Apolle, R.; Arabidze, G.; Aracena, I.; Arai, Y.; Arce, A. T. H.; Archambault, J. P.; Arfaoui, S.; Arguin, J.-F.; Arik, E.; Arik, M.; Armbruster, A. J.; Arnaez, O.; Arnault, C.; Artamonov, A.; Artoni, G.; Arutinov, D.; Asai, S.; Asfandiyarov, R.; Ask, S.; Åsman, B.; Asquith, L.; Assamagan, K.; Astbury, A.; Astvatsatourov, A.; Atoian, G.; Aubert, B.; Auerbach, B.; Auge, E.; Augsten, K.; Aurousseau, M.; Austin, N.; Avolio, G.; Avramidou, R.; Axen, D.; Ay, C.; Azuelos, G.; Azuma, Y.; Baak, M. A.; Baccaglioni, G.; Bacci, C.; Bach, A. M.; Bachacou, H.; Bachas, K.; Bachy, G.; Backes, M.; Backhaus, M.; Badescu, E.; Bagnaia, P.; Bahinipati, S.; Bai, Y.; Bailey, D. C.; Bain, T.; Baines, J. T.; Baker, O. K.; Baker, M. D.; Baker, S.; Baltasar Dos Santos Pedrosa, F.; Banas, E.; Banerjee, P.; Banerjee, Sw.; Banfi, D.; Bangert, A.; Bansal, V.; Bansil, H. S.; Barak, L.; Baranov, S. P.; Barashkou, A.; Barbaro Galtieri, A.; Barber, T.; Barberio, E. L.; Barberis, D.; Barbero, M.; Bardin, D. Y.; Barillari, T.; Barisonzi, M.; Barklow, T.; Barlow, N.; Barnett, B. M.; Barnett, R. M.; Baroncelli, A.; Barone, G.; Barr, A. J.; Barreiro, F.; Barreiro Guimarães da Costa, J.; Barrillon, P.; Bartoldus, R.; Barton, A. E.; Bartsch, D.; Bartsch, V.; Bates, R. L.; Batkova, L.; Batley, J. R.; Battaglia, A.; Battistin, M.; Battistoni, G.; Bauer, F.; Bawa, H. S.; Beare, B.; Beau, T.; Beauchemin, P. H.; Beccherle, R.; Bechtle, P.; Beck, H. P.; Beckingham, M.; Becks, K. H.; Beddall, A. J.; Beddall, A.; Bedikian, S.; Bednyakov, V. A.; Bee, C. P.; Begel, M.; Behar Harpaz, S.; Behera, P. K.; Beimforde, M.; Belanger-Champagne, C.; Bell, P. J.; Bell, W. H.; Bella, G.; Bellagamba, L.; Bellina, F.; Bellomo, M.; Belloni, A.; Beloborodova, O.; Belotskiy, K.; Beltramello, O.; Ben Ami, S.; Benary, O.; Benchekroun, D.; Benchouk, C.; Bendel, M.; Benedict, B. H.; Benekos, N.; Benhammou, Y.; Benjamin, D. P.; Benoit, M.; Bensinger, J. R.; Benslama, K.; Bentvelsen, S.; Berge, D.; Bergeaas Kuutmann, E.; Berger, N.; Berghaus, F.; Berglund, E.; Beringer, J.; Bernardet, K.; Bernat, P.; Bernhard, R.; Bernius, C.; Berry, T.; Bertin, A.; Bertinelli, F.; Bertolucci, F.; Besana, M. I.; Besson, N.; Bethke, S.; Bhimji, W.; Bianchi, R. M.; Bianco, M.; Biebel, O.; Bieniek, S. P.; Biesiada, J.; Biglietti, M.; Bilokon, H.; Bindi, M.; Binet, S.; Bingul, A.; Bini, C.; Biscarat, C.; Bitenc, U.; Black, K. M.; Blair, R. E.; Blanchard, J.-B.; Blanchot, G.; Blazek, T.; Blocker, C.; Blocki, J.; Blondel, A.; Blum, W.; Blumenschein, U.; Bobbink, G. J.; Bobrovnikov, V. B.; Bocchetta, S. S.; Bocci, A.; Boddy, C. R.; Boehler, M.; Boek, J.; Boelaert, N.; Böser, S.; Bogaerts, J. A.; Bogdanchikov, A.; Bogouch, A.; Bohm, C.; Boisvert, V.; Bold, T.; Boldea, V.; Bolnet, N. M.; Bona, M.; Bondarenko, V. G.; Boonekamp, M.; Boorman, G.; Booth, C. N.; Bordoni, S.; Borer, C.; Borisov, A.; Borissov, G.; Borjanovic, I.; Borroni, S.; Bos, K.; Boscherini, D.; Bosman, M.; Boterenbrood, H.; Botterill, D.; Bouchami, J.; Boudreau, J.; Bouhova-Thacker, E. V.; Boulahouache, C.; Bourdarios, C.; Bousson, N.; Boveia, A.; Boyd, J.; Boyko, I. R.; Bozhko, N. I.; Bozovic-Jelisavcic, I.; Bracinik, J.; Braem, A.; Branchini, P.; Brandenburg, G. W.; Brandt, A.; Brandt, G.; Brandt, O.; Bratzler, U.; Brau, B.; Brau, J. E.; Braun, H. M.; Brelier, B.; Bremer, J.; Brenner, R.; Bressler, S.; Breton, D.; Britton, D.; Brochu, F. M.; Brock, I.; Brock, R.; Brodbeck, T. J.; Brodet, E.; Broggi, F.; Bromberg, C.; Brooijmans, G.; Brooks, W. K.; Brown, G.; Brown, H.; Brubaker, E.; Bruckman de Renstrom, P. A.; Bruncko, D.; Bruneliere, R.; Brunet, S.; Bruni, A.; Bruni, G.; Bruschi, M.; Buanes, T.; Bucci, F.; Buchanan, J.; Buchanan, N. J.; Buchholz, P.; Buckingham, R. M.; Buckley, A. G.; Buda, S. I.; Budagov, I. A.; Budick, B.; Büscher, V.; Bugge, L.; Buira-Clark, D.; Bulekov, O.; Bunse, M.; Buran, T.; Burckhart, H.; Burdin, S.; Burgess, T.; Burke, S.; Busato, E.; Bussey, P.; Buszello, C. P.; Butin, F.; Butler, B.; Butler, J. M.; Buttar, C. M.; Butterworth, J. M.; Buttinger, W.; Byatt, T.; Cabrera Urbán, S.; Caforio, D.; Cakir, O.; Calafiura, P.; Calderini, G.; Calfayan, P.; Calkins, R.; Caloba, L. P.; Caloi, R.; Calvet, D.; Calvet, S.; Camacho Toro, R.; Camard, A.; Camarri, P.; Cambiaghi, M.; Cameron, D.; Cammin, J.; Campana, S.; Campanelli, M.; Canale, V.; Canelli, F.; Canepa, A.; Cantero, J.; Capasso, L.; Capeans Garrido, M. D. M.; Caprini, I.; Caprini, M.; Capriotti, D.; Capua, M.; Caputo, R.; Caramarcu, C.; Cardarelli, R.; Carli, T.; Carlino, G.; Carminati, L.; Caron, B.; Caron, S.; Carrillo Montoya, G. D.; Carter, A. A.; Carter, J. R.; Carvalho, J.; Casadei, D.; Casado, M. P.; Cascella, M.; Caso, C.; Castaneda Hernandez, A. M.; Castaneda-Miranda, E.; Castillo Gimenez, V.; Castro, N. F.; Cataldi, G.; Cataneo, F.; Catinaccio, A.; Catmore, J. R.; Cattai, A.; Cattani, G.; Caughron, S.; Cauz, D.; Cavalleri, P.; Cavalli, D.; Cavalli-Sforza, M.; Cavasinni, V.; Cazzato, A.; Ceradini, F.; Cerqueira, A. S.; Cerri, A.; Cerrito, L.; Cerutti, F.; Cetin, S. A.; Cevenini, F.; Chafaq, A.; Chakraborty, D.; Chan, K.; Chapleau, B.; Chapman, J. D.; Chapman, J. W.; Chareyre, E.; Charlton, D. G.; Chavda, V.; Cheatham, S.; Chekanov, S.; Chekulaev, S. V.; Chelkov, G. A.; Chelstowska, M. A.; Chen, C.; Chen, H.; Chen, L.; Chen, S.; Chen, T.; Chen, X.; Cheng, S.; Cheplakov, A.; Chepurnov, V. F.; Cherkaoui El Moursli, R.; Chernyatin, V.; Cheu, E.; Cheung, S. L.; Chevalier, L.; Chiefari, G.; Chikovani, L.; Childers, J. T.; Chilingarov, A.; Chiodini, G.; Chislett, R. T.; Chizhov, M. V.; Choudalakis, G.; Chouridou, S.; Christidi, I. A.; Christov, A.; Chromek-Burckhart, D.; Chu, M. L.; Chudoba, J.; Ciapetti, G.; Ciba, K.; Ciftci, A. K.; Ciftci, R.; Cinca, D.; Cindro, V.; Ciobotaru, M. D.; Ciocca, C.; Ciocio, A.; Cirilli, M.; Ciubancan, M.; Clark, A.; Clark, P. J.; Cleland, W.; Clemens, J. C.; Clement, B.; Clement, C.; Clifft, R. W.; Coadou, Y.; Cobal, M.; Coccaro, A.; Cochran, J.; Coe, P.; Cogan, J. G.; Coggeshall, J.; Cogneras, E.; Cojocaru, C. D.; Colas, J.; Colijn, A. P.; Collard, C.; Collins, N. J.; Collins-Tooth, C.; Collot, J.; Colon, G.; Conde Muiño, P.; Coniavitis, E.; Conidi, M. C.; Consonni, M.; Consorti, V.; Constantinescu, S.; Conta, C.; Conventi, F.; Cook, J.; Cooke, M.; Cooper, B. D.; Cooper-Sarkar, A. M.; Cooper-Smith, N. J.; Copic, K.; Cornelissen, T.; Corradi, M.; Corriveau, F.; Cortes-Gonzalez, A.; Cortiana, G.; Costa, G.; Costa, M. J.; Costanzo, D.; Costin, T.; Côté, D.; Coura Torres, R.; Courneyea, L.; Cowan, G.; Cowden, C.; Cox, B. E.; Cranmer, K.; Crescioli, F.; Cristinziani, M.; Crosetti, G.; Crupi, R.; Crépé-Renaudin, S.; Cuciuc, C.-M.; Cuenca Almenar, C.; Cuhadar Donszelmann, T.; Cuneo, S.; Curatolo, M.; Curtis, C. J.; Cwetanski, P.; Czirr, H.; Czyczula, Z.; D'Auria, S.; D'Onofrio, M.; D'Orazio, A.; Da Rocha Gesualdi Mello, A.; Da Silva, P. V. M.; Da Via, C.; Dabrowski, W.; Dahlhoff, A.; Dai, T.; Dallapiccola, C.; Dam, M.; Dameri, M.; Damiani, D. S.; Danielsson, H. O.; Dannheim, D.; Dao, V.; Darbo, G.; Darlea, G. L.; Daum, C.; Dauvergne, J. P.; Davey, W.; Davidek, T.; Davidson, N.; Davidson, R.; Davies, E.; Davies, M.; Davison, A. R.; Davygora, Y.; Dawe, E.; Dawson, I.; Dawson, J. W.; Daya, R. K.; De, K.; de Asmundis, R.; De Castro, S.; De Castro Faria Salgado, P. E.; De Cecco, S.; de Graat, J.; De Groot, N.; de Jong, P.; De La Taille, C.; De la Torre, H.; De Lotto, B.; De Mora, L.; De Nooij, L.; De Oliveira Branco, M.; De Pedis, D.; de Saintignon, P.; De Salvo, A.; De Sanctis, U.; De Santo, A.; De Vivie De Regie, J. B.; Dean, S.; Dedovich, D. V.; Degenhardt, J.; Dehchar, M.; Deile, M.; Del Papa, C.; Del Peso, J.; Del Prete, T.; Dell'Acqua, A.; Dell'Asta, L.; Della Pietra, M.; della Volpe, D.; Delmastro, M.; Delpierre, P.; Delruelle, N.; Delsart, P. A.; Deluca, C.; Demers, S.; Demichev, M.; Demirkoz, B.; Deng, J.; Denisov, S. P.; Derendarz, D.; Derkaoui, J. E.; Derue, F.; Dervan, P.; Desch, K.; Devetak, E.; Deviveiros, P. O.; Dewhurst, A.; DeWilde, B.; Dhaliwal, S.; Dhullipudi, R.; Di Ciaccio, A.; Di Ciaccio, L.; Di Girolamo, A.; Di Girolamo, B.; Di Luise, S.; Di Mattia, A.; Di Micco, B.; Di Nardo, R.; Di Simone, A.; Di Sipio, R.; Diaz, M. A.; Diblen, F.; Diehl, E. B.; Dieli, M. V.; Dietl, H.; Dietrich, J.; Dietzsch, T. A.; Diglio, S.; Dindar Yagci, K.; Dingfelder, J.; Dionisi, C.; Dita, P.; Dita, S.; Dittus, F.; Djama, F.; Djilkibaev, R.; Djobava, T.; do Vale, M. A. B.; Do Valle Wemans, A.; Doan, T. K. O.; Dobbs, M.; Dobinson, R.; Dobos, D.; Dobson, E.; Dobson, M.; Dodd, J.; Dogan, O. B.; Doglioni, C.; Doherty, T.; Doi, Y.; Dolejsi, J.; Dolenc, I.; Dolezal, Z.; Dolgoshein, B. A.; Dohmae, T.; Donadelli, M.; Donega, M.; Donini, J.; Dopke, J.; Doria, A.; Dos Anjos, A.; Dosil, M.; Dotti, A.; Dova, M. T.; Dowell, J. D.; Doxiadis, A. D.; Doyle, A. T.; Drasal, Z.; Drees, J.; Dressnandt, N.; Drevermann, H.; Driouichi, C.; Dris, M.; Dubbert, J.; Dubbs, T.; Dube, S.; Duchovni, E.; Duckeck, G.; Dudarev, A.; Dudziak, F.; Dührssen, M.; Duerdoth, I. P.; Duflot, L.; Dufour, M.-A.; Dunford, M.; Duran Yildiz, H.; Duxfield, R.; Dwuznik, M.; Dydak, F.; Dzahini, D.; Düren, M.; Ebenstein, W. L.; Ebke, J.; Eckert, S.; Eckweiler, S.; Edmonds, K.; Edwards, C. A.; Edwards, N. C.; Ehrenfeld, W.; Ehrich, T.; Eifert, T.; Eigen, G.; Einsweiler, K.; Eisenhandler, E.; Ekelof, T.; El Kacimi, M.; Ellert, M.; Elles, S.; Ellinghaus, F.; Ellis, K.; Ellis, N.; Elmsheuser, J.; Elsing, M.; Ely, R.; Emeliyanov, D.; Engelmann, R.; Engl, A.; Epp, B.; Eppig, A.; Erdmann, J.; Ereditato, A.; Eriksson, D.; Ernst, J.; Ernst, M.; Ernwein, J.; Errede, D.; Errede, S.; Ertel, E.; Escalier, M.; Escobar, C.; Espinal Curull, X.; Esposito, B.; Etienne, F.; Etienvre, A. I.; Etzion, E.; Evangelakou, D.; Evans, H.; Fabbri, L.; Fabre, C.; Fakhrutdinov, R. M.; Falciano, S.; Falou, A. C.; Fang, Y.; Fanti, M.; Farbin, A.; Farilla, A.; Farley, J.; Farooque, T.; Farrington, S. M.; Farthouat, P.; Fassnacht, P.; Fassouliotis, D.; Fatholahzadeh, B.; Favareto, A.; Fayard, L.; Fazio, S.; Febbraro, R.; Federic, P.; Fedin, O. L.; Fedorko, I.; Fedorko, W.; Fehling-Kaschek, M.; Feligioni, L.; Fellmann, D.; Felzmann, C. U.; Feng, C.; Feng, E. J.; Fenyuk, A. B.; Ferencei, J.; Ferland, J.; Fernando, W.; Ferrag, S.; Ferrando, J.; Ferrara, V.; Ferrari, A.; Ferrari, P.; Ferrari, R.; Ferrer, A.; Ferrer, M. L.; Ferrere, D.; Ferretti, C.; Ferretto Parodi, A.; Fiascaris, M.; Fiedler, F.; Filipčič, A.; Filippas, A.; Filthaut, F.; Fincke-Keeler, M.; Fiolhais, M. C. N.; Fiorini, L.; Firan, A.; Fischer, G.; Fischer, P.; Fisher, M. J.; Fisher, S. M.; Flechl, M.; Fleck, I.; Fleckner, J.; Fleischmann, P.; Fleischmann, S.; Flick, T.; Flores Castillo, L. R.; Flowerdew, M. J.; Föhlisch, F.; Fokitis, M.; Fonseca Martin, T.; Forbush, D. A.; Formica, A.; Forti, A.; Fortin, D.; Foster, J. M.; Fournier, D.; Foussat, A.; Fowler, A. J.; Fowler, K.; Fox, H.; Francavilla, P.; Franchino, S.; Francis, D.; Frank, T.; Franklin, M.; Franz, S.; Fraternali, M.; Fratina, S.; French, S. T.; Froeschl, R.; Froidevaux, D.; Frost, J. A.; Fukunaga, C.; Fullana Torregrosa, E.; Fuster, J.; Gabaldon, C.; Gabizon, O.; Gadfort, T.; Gadomski, S.; Gagliardi, G.; Gagnon, P.; Galea, C.; Gallas, E. J.; Gallas, M. V.; Gallo, V.; Gallop, B. J.; Gallus, P.; Galyaev, E.; Gan, K. K.; Gao, Y. S.; Gapienko, V. A.; Gaponenko, A.; Garberson, F.; Garcia-Sciveres, M.; García, C.; García Navarro, J. E.; Gardner, R. W.; Garelli, N.; Garitaonandia, H.; Garonne, V.; Garvey, J.; Gatti, C.; Gaudio, G.; Gaumer, O.; Gaur, B.; Gauthier, L.; Gavrilenko, I. L.; Gay, C.; Gaycken, G.; Gayde, J.-C.; Gazis, E. N.; Ge, P.; Gee, C. N. P.; Geerts, D. A. A.; Geich-Gimbel, Ch.; Gellerstedt, K.; Gemme, C.; Gemmell, A.; Genest, M. H.; Gentile, S.; George, M.; George, S.; Gerlach, P.; Gershon, A.; Geweniger, C.; Ghazlane, H.; Ghez, P.; Ghodbane, N.; Giacobbe, B.; Giagu, S.; Giakoumopoulou, V.; Giangiobbe, V.; Gianotti, F.; Gibbard, B.; Gibson, A.; Gibson, S. M.; Gilbert, L. M.; Gilchriese, M.; Gilewsky, V.; Gillberg, D.; Gillman, A. R.; Gingrich, D. M.; Ginzburg, J.; Giokaris, N.; Giordano, R.; Giorgi, F. M.; Giovannini, P.; Giraud, P. F.; Giugni, D.; Giunta, M.; Giusti, P.; Gjelsten, B. K.; Gladilin, L. K.; Glasman, C.; Glatzer, J.; Glazov, A.; Glitza, K. W.; Glonti, G. L.; Godfrey, J.; Godlewski, J.; Goebel, M.; Göpfert, T.; Goeringer, C.; Gössling, C.; Göttfert, T.; Goldfarb, S.; Goldin, D.; Golling, T.; Golovnia, S. N.; Gomes, A.; Gomez Fajardo, L. S.; Gonçalo, R.; Goncalves Pinto Firmino Da Costa, J.; Gonella, L.; Gonidec, A.; Gonzalez, S.; González de la Hoz, S.; Gonzalez Silva, M. L.; Gonzalez-Sevilla, S.; Goodson, J. J.; Goossens, L.; Gorbounov, P. A.; Gordon, H. A.; Gorelov, I.; Gorfine, G.; Gorini, B.; Gorini, E.; Gorišek, A.; Gornicki, E.; Gorokhov, S. A.; Goryachev, V. N.; Gosdzik, B.; Gosselink, M.; Gostkin, M. I.; Gouanère, M.; Gough Eschrich, I.; Gouighri, M.; Goujdami, D.; Goulette, M. P.; Goussiou, A. G.; Goy, C.; Grabowska-Bold, I.; Grabski, V.; Grafström, P.; Grah, C.; Grahn, K.-J.; Grancagnolo, F.; Grancagnolo, S.; Grassi, V.; Gratchev, V.; Grau, N.; Gray, H. M.; Gray, J. A.; Graziani, E.; Grebenyuk, O. G.; Greenfield, D.; Greenshaw, T.; Greenwood, Z. D.; Gregor, I. M.; Grenier, P.; Griesmayer, E.; Griffiths, J.; Grigalashvili, N.; Grillo, A. A.; Grinstein, S.; Grishkevich, Y. V.; Grivaz, J.-F.; Grognuz, J.; Groh, M.; Gross, E.; Grosse-Knetter, J.; Groth-Jensen, J.; Grybel, K.; Guarino, V. J.; Guest, D.; Guicheney, C.; Guida, A.; Guillemin, T.; Guindon, S.; Guler, H.; Gunther, J.; Guo, B.; Guo, J.; Gupta, A.; Gusakov, Y.; Gushchin, V. N.; Gutierrez, A.; Gutierrez, P.; Guttman, N.; Gutzwiller, O.; Guyot, C.; Gwenlan, C.; Gwilliam, C. B.; Haas, A.; Haas, S.; Haber, C.; Hackenburg, R.; Hadavand, H. K.; Hadley, D. R.; Haefner, P.; Hahn, F.; Haider, S.; Hajduk, Z.; Hakobyan, H.; Haller, J.; Hamacher, K.; Hamal, P.; Hamilton, A.; Hamilton, S.; Han, H.; Han, L.; Hanagaki, K.; Hance, M.; Handel, C.; Hanke, P.; Hansen, J. R.; Hansen, J. B.; Hansen, J. D.; Hansen, P. H.; Hansson, P.; Hara, K.; Hare, G. A.; Harenberg, T.; Harkusha, S.; Harper, D.; Harrington, R. D.; Harris, O. M.; Harrison, K.; Hartert, J.; Hartjes, F.; Haruyama, T.; Harvey, A.; Hasegawa, S.; Hasegawa, Y.; Hassani, S.; Hatch, M.; Hauff, D.; Haug, S.; Hauschild, M.; Hauser, R.; Havranek, M.; Hawes, B. M.; Hawkes, C. M.; Hawkings, R. J.; Hawkins, D.; Hayakawa, T.; Hayden, D.; Hayward, H. S.; Haywood, S. J.; Hazen, E.; He, M.; Head, S. J.; Hedberg, V.; Heelan, L.; Heim, S.; Heine, K.; Heinemann, B.; Heisterkamp, S.; Helary, L.; Heldmann, M.; Heller, M.; Hellman, S.; Helsens, C.; Henderson, R. C. W.; Henke, M.; Henrichs, A.; Henriques Correia, A. M.; Henrot-Versille, S.; Henry-Couannier, F.; Hensel, C.; Henß, T.; Hernandez, C. M.; Hernández Jiménez, Y.; Herrberg, R.; Hershenhorn, A. D.; Herten, G.; Hertenberger, R.; Hervas, L.; Hessey, N. P.; Hidvegi, A.; Higón-Rodriguez, E.; Hill, D.; Hill, J. C.; Hill, N.; Hiller, K. H.; Hillert, S.; Hillier, S. J.; Hinchliffe, I.; Hines, E.; Hirose, M.; Hirsch, F.; Hirschbuehl, D.; Hobbs, J.; Hod, N.; Hodgkinson, M. C.; Hodgson, P.; Hoecker, A.; Hoeferkamp, M. R.; Hoffman, J.; Hoffmann, D.; Hohlfeld, M.; Holder, M.; Holmes, A.; Holmgren, S. O.; Holy, T.; Holzbauer, J. L.; Homma, Y.; Hong, T. M.; Hooft van Huysduynen, L.; Horazdovsky, T.; Horn, C.; Horner, S.; Horton, K.; Hostachy, J.-Y.; Hou, S.; Houlden, M. A.; Hoummada, A.; Howarth, J.; Howell, D. F.; Hristova, I.; Hrivnac, J.; Hruska, I.; Hryn'ova, T.; Hsu, P. J.; Hsu, S.-C.; Huang, G. S.; Hubacek, Z.; Hubaut, F.; Huegging, F.; Huffman, T. B.; Hughes, E. W.; Hughes, G.; Hughes-Jones, R. E.; Huhtinen, M.; Hurst, P.; Hurwitz, M.; Husemann, U.; Huseynov, N.; Huston, J.; Huth, J.; Iacobucci, G.; Iakovidis, G.; Ibbotson, M.; Ibragimov, I.; Ichimiya, R.; Iconomidou-Fayard, L.; Idarraga, J.; Idzik, M.; Iengo, P.; Igonkina, O.; Ikegami, Y.; Ikeno, M.; Ilchenko, Y.; Iliadis, D.; Imbault, D.; Imhaeuser, M.; Imori, M.; Ince, T.; Inigo-Golfin, J.; Ioannou, P.; Iodice, M.; Ionescu, G.; Irles Quiles, A.; Ishii, K.; Ishikawa, A.; Ishino, M.; Ishmukhametov, R.; Issever, C.; Istin, S.; Itoh, Y.; Ivashin, A. V.; Iwanski, W.; Iwasaki, H.; Izen, J. M.; Izzo, V.; Jackson, B.; Jackson, J. N.; Jackson, P.; Jaekel, M. R.; Jain, V.; Jakobs, K.; Jakobsen, S.; Jakubek, J.; Jana, D. K.; Jankowski, E.; Jansen, E.; Jantsch, A.; Janus, M.; Jarlskog, G.; Jeanty, L.; Jelen, K.; Jen-La Plante, I.; Jenni, P.; Jeremie, A.; Jež, P.; Jézéquel, S.; Jha, M. K.; Ji, H.; Ji, W.; Jia, J.; Jiang, Y.; Jimenez Belenguer, M.; Jin, G.; Jin, S.; Jinnouchi, O.; Joergensen, M. D.; Joffe, D.; Johansen, L. G.; Johansen, M.; Johansson, K. E.; Johansson, P.; Johnert, S.; Johns, K. A.; Jon-And, K.; Jones, G.; Jones, R. W. L.; Jones, T. W.; Jones, T. J.; Jonsson, O.; Joram, C.; Jorge, P. M.; Joseph, J.; Ju, X.; Juranek, V.; Jussel, P.; Kabachenko, V. V.; Kabana, S.; Kaci, M.; Kaczmarska, A.; Kadlecik, P.; Kado, M.; Kagan, H.; Kagan, M.; Kaiser, S.; Kajomovitz, E.; Kalinin, S.; Kalinovskaya, L. V.; Kama, S.; Kanaya, N.; Kaneda, M.; Kanno, T.; Kantserov, V. A.; Kanzaki, J.; Kaplan, B.; Kapliy, A.; Kaplon, J.; Kar, D.; Karagoz, M.; Karnevskiy, M.; Karr, K.; Kartvelishvili, V.; Karyukhin, A. N.; Kashif, L.; Kasmi, A.; Kass, R. D.; Kastanas, A.; Kataoka, M.; Kataoka, Y.; Katsoufis, E.; Katzy, J.; Kaushik, V.; Kawagoe, K.; Kawamoto, T.; Kawamura, G.; Kayl, M. S.; Kazanin, V. A.; Kazarinov, M. Y.; Keates, J. R.; Keeler, R.; Kehoe, R.; Keil, M.; Kekelidze, G. D.; Kelly, M.; Kennedy, J.; Kenney, C. J.; Kenyon, M.; Kepka, O.; Kerschen, N.; Kerševan, B. P.; Kersten, S.; Kessoku, K.; Ketterer, C.; Keung, J.; Khakzad, M.; Khalil-zada, F.; Khandanyan, H.; Khanov, A.; Kharchenko, D.; Khodinov, A.; Kholodenko, A. G.; Khomich, A.; Khoo, T. J.; Khoriauli, G.; Khoroshilov, A.; Khovanskiy, N.; Khovanskiy, V.; Khramov, E.; Khubua, J.; Kim, H.; Kim, M. S.; Kim, P. C.; Kim, S. H.; Kimura, N.; Kind, O.; King, B. T.; King, M.; King, R. S. B.; Kirk, J.; Kirsch, G. P.; Kirsch, L. E.; Kiryunin, A. E.; Kisielewska, D.; Kittelmann, T.; Kiver, A. M.; Kiyamura, H.; Kladiva, E.; Klaiber-Lodewigs, J.; Klein, M.; Klein, U.; Kleinknecht, K.; Klemetti, M.; Klier, A.; Klimentov, A.; Klingenberg, R.; Klinkby, E. B.; Klioutchnikova, T.; Klok, P. F.; Klous, S.; Kluge, E.-E.; Kluge, T.; Kluit, P.; Kluth, S.; Kneringer, E.; Knobloch, J.; Knoops, E. B. F. G.; Knue, A.; Ko, B. R.; Kobayashi, T.; Kobel, M.; Kocian, M.; Kocnar, A.; Kodys, P.; Köneke, K.; König, A. C.; Koenig, S.; Köpke, L.; Koetsveld, F.; Koevesarki, P.; Koffas, T.; Koffeman, E.; Kohn, F.; Kohout, Z.; Kohriki, T.; Koi, T.; Kokott, T.; Kolachev, G. M.; Kolanoski, H.; Kolesnikov, V.; Koletsou, I.; Koll, J.; Kollar, D.; Kollefrath, M.; Kolya, S. D.; Komar, A. A.; Komaragiri, J. R.; Komori, Y.; Kondo, T.; Kono, T.; Kononov, A. I.; Konoplich, R.; Konstantinidis, N.; Kootz, A.; Koperny, S.; Kopikov, S. V.; Korcyl, K.; Kordas, K.; Koreshev, V.; Korn, A.; Korol, A.; Korolkov, I.; Korolkova, E. V.; Korotkov, V. A.; Kortner, O.; Kortner, S.; Kostyukhin, V. V.; Kotamäki, M. J.; Kotov, S.; Kotov, V. M.; Kotwal, A.; Kourkoumelis, C.; Kouskoura, V.; Koutsman, A.; Kowalewski, R.; Kowalski, T. Z.; Kozanecki, W.; Kozhin, A. S.; Kral, V.; Kramarenko, V. A.; Kramberger, G.; Krasel, O.; Krasny, M. W.; Krasznahorkay, A.; Kraus, J.; Kreisel, A.; Krejci, F.; Kretzschmar, J.; Krieger, N.; Krieger, P.; Kroeninger, K.; Kroha, H.; Kroll, J.; Kroseberg, J.; Krstic, J.; Kruchonak, U.; Krüger, H.; Kruker, T.; Krumshteyn, Z. V.; Kruth, A.; Kubota, T.; Kuehn, S.; Kugel, A.; Kuhl, T.; Kuhn, D.; Kukhtin, V.; Kulchitsky, Y.; Kuleshov, S.; Kummer, C.; Kuna, M.; Kundu, N.; Kunkle, J.; Kupco, A.; Kurashige, H.; Kurata, M.; Kurochkin, Y. A.; Kus, V.; Kuykendall, W.; Kuze, M.; Kuzhir, P.; Kvasnicka, O.; Kvita, J.; Kwee, R.; La Rosa, A.; La Rotonda, L.; Labarga, L.; Labbe, J.; Lablak, S.; Lacasta, C.; Lacava, F.; Lacker, H.; Lacour, D.; Lacuesta, V. R.; Ladygin, E.; Lafaye, R.; Laforge, B.; Lagouri, T.; Lai, S.; Laisne, E.; Lamanna, M.; Lampen, C. L.; Lampl, W.; Lancon, E.; Landgraf, U.; Landon, M. P. J.; Landsman, H.; Lane, J. L.; Lange, C.; Lankford, A. J.; Lanni, F.; Lantzsch, K.; Lapin, V. V.; Laplace, S.; Lapoire, C.; Laporte, J. F.; Lari, T.; Larionov, A. V.; Larner, A.; Lasseur, C.; Lassnig, M.; Lau, W.; Laurelli, P.; Lavorato, A.; Lavrijsen, W.; Laycock, P.; Lazarev, A. B.; Lazzaro, A.; Le Dortz, O.; Le Guirriec, E.; Le Maner, C.; Le Menedeu, E.; Lebedev, A.; Lebel, C.; LeCompte, T.; Ledroit-Guillon, F.; Lee, H.; Lee, J. S. H.; Lee, S. C.; Lee, L.; Lefebvre, M.; Legendre, M.; Leger, A.; LeGeyt, B. C.; Legger, F.; Leggett, C.; Lehmacher, M.; Lehmann Miotto, G.; Lei, X.; Leite, M. A. L.; Leitner, R.; Lellouch, D.; Leltchouk, M.; Lendermann, V.; Leney, K. J. C.; Lenz, T.; Lenzen, G.; Lenzi, B.; Leonhardt, K.; Leontsinis, S.; Leroy, C.; Lessard, J.-R.; Lesser, J.; Lester, C. G.; Leung Fook Cheong, A.; Levêque, J.; Levin, D.; Levinson, L. J.; Levitski, M. S.; Lewandowska, M.; Lewis, A.; Lewis, G. H.; Leyko, A. M.; Leyton, M.; Li, B.; Li, H.; Li, S.; Li, X.; Liang, Z.; Liang, Z.; Liberti, B.; Lichard, P.; Lichtnecker, M.; Lie, K.; Liebig, W.; Lifshitz, R.; Lilley, J. N.; Limbach, C.; Limosani, A.; Limper, M.; Lin, S. C.; Linde, F.; Linnemann, J. T.; Lipeles, E.; Lipinsky, L.; Lipniacka, A.; Liss, T. M.; Lissauer, D.; Lister, A.; Litke, A. M.; Liu, C.; Liu, D.; Liu, H.; Liu, J. B.; Liu, M.; Liu, S.; Liu, Y.; Livan, M.; Livermore, S. S. A.; Lleres, A.; Llorente Merino, J.; Lloyd, S. L.; Lobodzinska, E.; Loch, P.; Lockman, W. S.; Lockwitz, S.; Loddenkoetter, T.; Loebinger, F. K.; Loginov, A.; Loh, C. W.; Lohse, T.; Lohwasser, K.; Lokajicek, M.; Loken, J.; Lombardo, V. P.; Long, R. E.; Lopes, L.; Lopez Mateos, D.; Losada, M.; Loscutoff, P.; Lo Sterzo, F.; Losty, M. J.; Lou, X.; Lounis, A.; Loureiro, K. F.; Love, J.; Love, P. A.; Lowe, A. J.; Lu, F.; Lu, L.; Lubatti, H. J.; Luci, C.; Lucotte, A.; Ludwig, A.; Ludwig, D.; Ludwig, I.; Ludwig, J.; Luehring, F.; Luijckx, G.; Lumb, D.; Luminari, L.; Lund, E.; Lund-Jensen, B.; Lundberg, B.; Lundberg, J.; Lundquist, J.; Lungwitz, M.; Lupi, A.; Lutz, G.; Lynn, D.; Lys, J.; Lytken, E.; Ma, H.; Ma, L. L.; Macana Goia, J. A.; Maccarrone, G.; Macchiolo, A.; Maček, B.; Machado Miguens, J.; Mackeprang, R.; Madaras, R. J.; Mader, W. F.; Maenner, R.; Maeno, T.; Mättig, P.; Mättig, S.; Magalhaes Martins, P. J.; Magnoni, L.; Magradze, E.; Mahalalel, Y.; Mahboubi, K.; Mahout, G.; Maiani, C.; Maidantchik, C.; Maio, A.; Majewski, S.; Makida, Y.; Makovec, N.; Mal, P.; Malecki, Pa.; Malecki, P.; Maleev, V. P.; Malek, F.; Mallik, U.; Malon, D.; Maltezos, S.; Malyshev, V.; Malyukov, S.; Mameghani, R.; Mamuzic, J.; Manabe, A.; Mandelli, L.; Mandić, I.; Mandrysch, R.; Maneira, J.; Mangeard, P. S.; Manjavidze, I. D.; Mann, A.; Manning, P. M.; Manousakis-Katsikakis, A.; Mansoulie, B.; Manz, A.; Mapelli, A.; Mapelli, L.; March, L.; Marchand, J. F.; Marchese, F.; Marchiori, G.; Marcisovsky, M.; Marin, A.; Marino, C. P.; Marroquim, F.; Marshall, R.; Marshall, Z.; Martens, F. K.; Marti-Garcia, S.; Martin, A. J.; Martin, B.; Martin, B.; Martin, F. F.; Martin, J. P.; Martin, Ph.; Martin, T. A.; Martin dit Latour, B.; Martinez, M.; Martinez Outschoorn, V.; Martyniuk, A. C.; Marx, M.; Marzano, F.; Marzin, A.; Masetti, L.; Mashimo, T.; Mashinistov, R.; Masik, J.; Maslennikov, A. L.; Maß, M.; Massa, I.; Massaro, G.; Massol, N.; Mastrandrea, P.; Mastroberardino, A.; Masubuchi, T.; Mathes, M.; Matricon, P.; Matsumoto, H.; Matsunaga, H.; Matsushita, T.; Mattravers, C.; Maugain, J. M.; Maxfield, S. J.; Maximov, D. A.; May, E. N.; Mayne, A.; Mazini, R.; Mazur, M.; Mazzanti, M.; Mazzoni, E.; Mc Kee, S. P.; McCarn, A.; McCarthy, R. L.; McCarthy, T. G.; McCubbin, N. A.; McFarlane, K. W.; Mcfayden, J. A.; McGlone, H.; Mchedlidze, G.; McLaren, R. A.; Mclaughlan, T.; McMahon, S. J.; McPherson, R. A.; Meade, A.; Mechnich, J.; Mechtel, M.; Medinnis, M.; Meera-Lebbai, R.; Meguro, T.; Mehdiyev, R.; Mehlhase, S.; Mehta, A.; Meier, K.; Meinhardt, J.; Meirose, B.; Melachrinos, C.; Mellado Garcia, B. R.; Mendoza Navas, L.; Meng, Z.; Mengarelli, A.; Menke, S.; Menot, C.; Meoni, E.; Mercurio, K. M.; Mermod, P.; Merola, L.; Meroni, C.; Merritt, F. S.; Messina, A.; Metcalfe, J.; Mete, A. S.; Meuser, S.; Meyer, C.; Meyer, J.-P.; Meyer, J.; Meyer, J.; Meyer, T. C.; Meyer, W. T.; Miao, J.; Michal, S.; Micu, L.; Middleton, R. P.; Miele, P.; Migas, S.; Mijović, L.; Mikenberg, G.; Mikestikova, M.; Mikuž, M.; Miller, D. W.; Miller, R. J.; Mills, W. J.; Mills, C.; Milov, A.; Milstead, D. A.; Milstein, D.; Minaenko, A. A.; Miñano, M.; Minashvili, I. A.; Mincer, A. I.; Mindur, B.; Mineev, M.; Ming, Y.; Mir, L. M.; Mirabelli, G.; Miralles Verge, L.; Misiejuk, A.; Mitrevski, J.; Mitrofanov, G. Y.; Mitsou, V. A.; Mitsui, S.; Miyagawa, P. S.; Miyazaki, K.; Mjörnmark, J. U.; Moa, T.; Mockett, P.; Moed, S.; Moeller, V.; Mönig, K.; Möser, N.; Mohapatra, S.; Mohn, B.; Mohr, W.; Mohrdieck-Möck, S.; Moisseev, A. M.; Moles-Valls, R.; Molina-Perez, J.; Monk, J.; Monnier, E.; Montesano, S.; Monticelli, F.; Monzani, S.; Moore, R. W.; Moorhead, G. F.; Mora Herrera, C.; Moraes, A.; Morais, A.; Morange, N.; Morel, J.; Morello, G.; Moreno, D.; Moreno Llácer, M.; Morettini, P.; Morii, M.; Morin, J.; Morita, Y.; Morley, A. K.; Mornacchi, G.; Morone, M.-C.; Morozov, S. V.; Morris, J. D.; Morvaj, L.; Moser, H. G.; Mosidze, M.; Moss, J.; Mount, R.; Mountricha, E.; Mouraviev, S. V.; Moyse, E. J. W.; Mudrinic, M.; Mueller, F.; Mueller, J.; Mueller, K.; Müller, T. A.; Muenstermann, D.; Muijs, A.; Muir, A.; Munwes, Y.; Murakami, K.; Murray, W. J.; Mussche, I.; Musto, E.; Myagkov, A. G.; Myska, M.; Nadal, J.; Nagai, K.; Nagano, K.; Nagasaka, Y.; Nairz, A. M.; Nakahama, Y.; Nakamura, K.; Nakano, I.; Nanava, G.; Napier, A.; Nash, M.; Nation, N. R.; Nattermann, T.; Naumann, T.; Navarro, G.; Neal, H. A.; Nebot, E.; Nechaeva, P. Yu.; Negri, A.; Negri, G.; Nektarijevic, S.; Nelson, A.; Nelson, S.; Nelson, T. K.; Nemecek, S.; Nemethy, P.; Nepomuceno, A. A.; Nessi, M.; Nesterov, S. Y.; Neubauer, M. S.; Neusiedl, A.; Neves, R. M.; Nevski, P.; Newman, P. R.; Nguyen Thi Hong, V.; Nickerson, R. B.; Nicolaidou, R.; Nicolas, L.; Nicquevert, B.; Niedercorn, F.; Nielsen, J.; Niinikoski, T.; Nikiforov, A.; Nikolaenko, V.; Nikolaev, K.; Nikolic-Audit, I.; Nikolopoulos, K.; Nilsen, H.; Nilsson, P.; Ninomiya, Y.; Nisati, A.; Nishiyama, T.; Nisius, R.; Nodulman, L.; Nomachi, M.; Nomidis, I.; Nomoto, H.; Nordberg, M.; Nordkvist, B.; Norton, P. R.; Novakova, J.; Nozaki, M.; Nožička, M.; Nozka, L.; Nugent, I. M.; Nuncio-Quiroz, A.-E.; Nunes Hanninger, G.; Nunnemann, T.; Nurse, E.; Nyman, T.; O'Brien, B. J.; O'Neale, S. W.; O'Neil, D. C.; O'Shea, V.; Oakham, F. G.; Oberlack, H.; Ocariz, J.; Ochi, A.; Oda, S.; Odaka, S.; Odier, J.; Ogren, H.; Oh, A.; Oh, S. H.; Ohm, C. C.; Ohshima, T.; Ohshita, H.; Ohska, T. K.; Ohsugi, T.; Okada, S.; Okawa, H.; Okumura, Y.; Okuyama, T.; Olcese, M.; Olchevski, A. G.; Oliveira, M.; Oliveira Damazio, D.; Oliver Garcia, E.; Olivito, D.; Olszewski, A.; Olszowska, J.; Omachi, C.; Onofre, A.; Onyisi, P. U. E.; Oram, C. J.; Oreglia, M. J.; Oren, Y.; Orestano, D.; Orlov, I.; Oropeza Barrera, C.; Orr, R. S.; Ortega, E. O.; Osculati, B.; Ospanov, R.; Osuna, C.; Otero y Garzon, G.; Ottersbach, J. P.; Ouchrif, M.; Ould-Saada, F.; Ouraou, A.; Ouyang, Q.; Owen, M.; Owen, S.; Øye, O. K.; Ozcan, V. E.; Ozturk, N.; Pacheco Pages, A.; Padilla Aranda, C.; Paganis, E.; Paige, F.; Pajchel, K.; Palestini, S.; Pallin, D.; Palma, A.; Palmer, J. D.; Pan, Y. B.; Panagiotopoulou, E.; Panes, B.; Panikashvili, N.; Panitkin, S.; Pantea, D.; Panuskova, M.; Paolone, V.; Papadelis, A.; Papadopoulou, Th. D.; Paramonov, A.; Park, W.; Parker, M. A.; Parodi, F.; Parsons, J. A.; Parzefall, U.; Pasqualucci, E.; Passeri, A.; Pastore, F.; Pastore, Fr.; Pásztor, G.; Pataraia, S.; Patel, N.; Pater, J. R.; Patricelli, S.; Pauly, T.; Pecsy, M.; Pedraza Morales, M. I.; Peleganchuk, S. V.; Peng, H.; Pengo, R.; Penson, A.; Penwell, J.; Perantoni, M.; Perez, K.; Perez Cavalcanti, T.; Perez Codina, E.; Pérez García-Estañ, M. T.; Perez Reale, V.; Peric, I.; Perini, L.; Pernegger, H.; Perrino, R.; Perrodo, P.; Persembe, S.; Peshekhonov, V. D.; Peters, O.; Petersen, B. A.; Petersen, J.; Petersen, T. C.; Petit, E.; Petridis, A.; Petridou, C.; Petrolo, E.; Petrucci, F.; Petschull, D.; Petteni, M.; Pezoa, R.; Phan, A.; Phillips, A. W.; Phillips, P. W.; Piacquadio, G.; Piccaro, E.; Piccinini, M.; Pickford, A.; Piec, S. M.; Piegaia, R.; Pilcher, J. E.; Pilkington, A. D.; Pina, J.; Pinamonti, M.; Pinder, A.; Pinfold, J. L.; Ping, J.; Pinto, B.; Pirotte, O.; Pizio, C.; Placakyte, R.; Plamondon, M.; Plano, W. G.; Pleier, M.-A.; Pleskach, A. V.; Poblaguev, A.; Poddar, S.; Podlyski, F.; Poggioli, L.; Poghosyan, T.; Pohl, M.; Polci, F.; Polesello, G.; Policicchio, A.; Polini, A.; Poll, J.; Polychronakos, V.; Pomarede, D. M.; Pomeroy, D.; Pommès, K.; Pontecorvo, L.; Pope, B. G.; Popeneciu, G. A.; Popovic, D. S.; Poppleton, A.; Portell Bueso, X.; Porter, R.; Posch, C.; Pospelov, G. E.; Pospisil, S.; Potrap, I. N.; Potter, C. J.; Potter, C. T.; Poulard, G.; Poveda, J.; Prabhu, R.; Pralavorio, P.; Prasad, S.; Pravahan, R.; Prell, S.; Pretzl, K.; Pribyl, L.; Price, D.; Price, L. E.; Price, M. J.; Prichard, P. M.; Prieur, D.; Primavera, M.; Prokofiev, K.; Prokoshin, F.; Protopopescu, S.; Proudfoot, J.; Prudent, X.; Przysiezniak, H.; Psoroulas, S.; Ptacek, E.; Purdham, J.; Purohit, M.; Puzo, P.; Pylypchenko, Y.; Qian, J.; Qian, Z.; Qin, Z.; Quadt, A.; Quarrie, D. R.; Quayle, W. B.; Quinonez, F.; Raas, M.; Radescu, V.; Radics, B.; Rador, T.; Ragusa, F.; Rahal, G.; Rahimi, A. M.; Rahm, D.; Rajagopalan, S.; Rammensee, M.; Rammes, M.; Ramstedt, M.; Randrianarivony, K.; Ratoff, P. N.; Rauscher, F.; Rauter, E.; Raymond, M.; Read, A. L.; Rebuzzi, D. M.; Redelbach, A.; Redlinger, G.; Reece, R.; Reeves, K.; Reichold, A.; Reinherz-Aronis, E.; Reinsch, A.; Reisinger, I.; Reljic, D.; Rembser, C.; Ren, Z. L.; Renaud, A.; Renkel, P.; Rensch, B.; Rescigno, M.; Resconi, S.; Resende, B.; Reznicek, P.; Rezvani, R.; Richards, A.; Richter, R.; Richter-Was, E.; Ridel, M.; Rieke, S.; Rijpstra, M.; Rijssenbeek, M.; Rimoldi, A.; Rinaldi, L.; Rios, R. R.; Riu, I.; Rivoltella, G.; Rizatdinova, F.; Rizvi, E.; Robertson, S. H.; Robichaud-Veronneau, A.; Robinson, D.; Robinson, J. E. M.; Robinson, M.; Robson, A.; Rocha de Lima, J. G.; Roda, C.; Roda Dos Santos, D.; Rodier, S.; Rodriguez, D.; Rodriguez Garcia, Y.; Roe, A.; Roe, S.; Røhne, O.; Rojo, V.; Rolli, S.; Romaniouk, A.; Romanov, V. M.; Romeo, G.; Romero Maltrana, D.; Roos, L.; Ros, E.; Rosati, S.; Rosbach, K.; Rose, M.; Rosenbaum, G. A.; Rosenberg, E. I.; Rosendahl, P. L.; Rosselet, L.; Rossetti, V.; Rossi, E.; Rossi, L. P.; Rossi, L.; Rotaru, M.; Roth, I.; Rothberg, J.; Rousseau, D.; Royon, C. R.; Rozanov, A.; Rozen, Y.; Ruan, X.; Rubinskiy, I.; Ruckert, B.; Ruckstuhl, N.; Rud, V. I.; Rudolph, G.; Rühr, F.; Ruggieri, F.; Ruiz-Martinez, A.; Rulikowska-Zarebska, E.; Rumiantsev, V.; Rumyantsev, L.; Runge, K.; Runolfsson, O.; Rurikova, Z.; Rusakovich, N. A.; Rust, D. R.; Rutherfoord, J. P.; Ruwiedel, C.; Ruzicka, P.; Ryabov, Y. F.; Ryadovikov, V.; Ryan, P.; Rybar, M.; Rybkin, G.; Ryder, N. C.; Rzaeva, S.; Saavedra, A. F.; Sadeh, I.; Sadrozinski, H. F.-W.; Sadykov, R.; Safai Tehrani, F.; Sakamoto, H.; Salamanna, G.; Salamon, A.; Saleem, M.; Salihagic, D.; Salnikov, A.; Salt, J.; Salvachua Ferrando, B. M.; Salvatore, D.; Salvatore, F.; Salvucci, A.; Salzburger, A.; Sampsonidis, D.; Samset, B. H.; Sandaker, H.; Sander, H. G.; Sanders, M. P.; Sandhoff, M.; Sandoval, T.; Sandstroem, R.; Sandvoss, S.; Sankey, D. P. C.; Sansoni, A.; Santamarina Rios, C.; Santoni, C.; Santonico, R.; Santos, H.; Saraiva, J. G.; Sarangi, T.; Sarkisyan-Grinbaum, E.; Sarri, F.; Sartisohn, G.; Sasaki, O.; Sasaki, T.; Sasao, N.; Satsounkevitch, I.; Sauvage, G.; Sauvan, J. B.; Savard, P.; Savinov, V.; Savu, D. O.; Savva, P.; Sawyer, L.; Saxon, D. H.; Says, L. P.; Sbarra, C.; Sbrizzi, A.; Scallon, O.; Scannicchio, D. A.; Scarcella, M.; Schaarschmidt, J.; Schacht, P.; Schäfer, U.; Schaepe, S.; Schaetzel, S.; Schaffer, A. C.; Schaile, D.; Schamberger, R. D.; Schamov, A. G.; Scharf, V.; Schegelsky, V. A.; Scheirich, D.; Schernau, M.; Scherzer, M. I.; Schiavi, C.; Schieck, J.; Schioppa, M.; Schlenker, S.; Schlereth, J. L.; Schmidt, E.; Schmidt, M. P.; Schmieden, K.; Schmitt, C.; Schmitt, S.; Schmitz, M.; Schöning, A.; Schott, M.; Schouten, D.; Schovancova, J.; Schram, M.; Schroeder, C.; Schroer, N.; Schuh, S.; Schuler, G.; Schultes, J.; Schultz-Coulon, H.-C.; Schulz, H.; Schumacher, J. W.; Schumacher, M.; Schumm, B. A.; Schune, Ph.; Schwanenberger, C.; Schwartzman, A.; Schwemling, Ph.; Schwienhorst, R.; Schwierz, R.; Schwindling, J.; Scott, W. G.; Searcy, J.; Sedykh, E.; Segura, E.; Seidel, S. C.; Seiden, A.; Seifert, F.; Seixas, J. M.; Sekhniaidze, G.; Seliverstov, D. M.; Sellden, B.; Sellers, G.; Seman, M.; Semprini-Cesari, N.; Serfon, C.; Serin, L.; Seuster, R.; Severini, H.; Sevior, M. E.; Sfyrla, A.; Shabalina, E.; Shamim, M.; Shan, L. Y.; Shank, J. T.; Shao, Q. T.; Shapiro, M.; Shatalov, P. B.; Shaver, L.; Shaw, C.; Shaw, K.; Sherman, D.; Sherwood, P.; Shibata, A.; Shichi, H.; Shimizu, S.; Shimojima, M.; Shin, T.; Shmeleva, A.; Shochet, M. J.; Short, D.; Shupe, M. A.; Sicho, P.; Sidoti, A.; Siebel, A.; Siegert, F.; Siegrist, J.; Sijacki, Dj.; Silbert, O.; Silva, J.; Silver, Y.; Silverstein, D.; Silverstein, S. B.; Simak, V.; Simard, O.; Simic, Lj.; Simion, S.; Simmons, B.; Simonyan, M.; Sinervo, P.; Sinev, N. B.; Sipica, V.; Siragusa, G.; Sisakyan, A. N.; Sivoklokov, S. Yu.; Sjölin, J.; Sjursen, T. B.; Skinnari, L. A.; Skovpen, K.; Skubic, P.; Skvorodnev, N.; Slater, M.; Slavicek, T.; Sliwa, K.; Sloan, T. J.; Sloper, J.; Smakhtin, V.; Smirnov, S. Yu.; Smirnova, L. N.; Smirnova, O.; Smith, B. C.; Smith, D.; Smith, K. M.; Smizanska, M.; Smolek, K.; Snesarev, A. A.; Snow, S. W.; Snow, J.; Snuverink, J.; Snyder, S.; Soares, M.; Sobie, R.; Sodomka, J.; Soffer, A.; Solans, C. A.; Solar, M.; Solc, J.; Soldatov, E.; Soldevila, U.; Solfaroli Camillocci, E.; Solodkov, A. A.; Solovyanov, O. V.; Sondericker, J.; Soni, N.; Sopko, V.; Sopko, B.; Sorbi, M.; Sosebee, M.; Soukharev, A.; Spagnolo, S.; Spanò, F.; Spighi, R.; Spigo, G.; Spila, F.; Spiriti, E.; Spiwoks, R.; Spousta, M.; Spreitzer, T.; Spurlock, B.; St. Denis, R. D.; Stahl, T.; Stahlman, J.; Stamen, R.; Stanecka, E.; Stanek, R. W.; Stanescu, C.; Stapnes, S.; Starchenko, E. A.; Stark, J.; Staroba, P.; Starovoitov, P.; Staude, A.; Stavina, P.; Stavropoulos, G.; Steele, G.; Steinbach, P.; Steinberg, P.; Stekl, I.; Stelzer, B.; Stelzer, H. J.; Stelzer-Chilton, O.; Stenzel, H.; Stevenson, K.; Stewart, G. A.; Stillings, J. A.; Stockmanns, T.; Stockton, M. C.; Stoerig, K.; Stoicea, G.; Stonjek, S.; Strachota, P.; Stradling, A. R.; Straessner, A.; Strandberg, J.; Strandberg, S.; Strandlie, A.; Strang, M.; Strauss, E.; Strauss, M.; Strizenec, P.; Ströhmer, R.; Strom, D. M.; Strong, J. A.; Stroynowski, R.; Strube, J.; Stugu, B.; Stumer, I.; Stupak, J.; Sturm, P.; Soh, D. A.; Su, D.; Subramania, HS.; Succurro, A.; Sugaya, Y.; Sugimoto, T.; Suhr, C.; Suita, K.; Suk, M.; Sulin, V. V.; Sultansoy, S.; Sumida, T.; Sun, X.; Sundermann, J. E.; Suruliz, K.; Sushkov, S.; Susinno, G.; Sutton, M. R.; Suzuki, Y.; Svatos, M.; Sviridov, Yu. M.; Swedish, S.; Sykora, I.; Sykora, T.; Szeless, B.; Sánchez, J.; Ta, D.; Tackmann, K.; Taffard, A.; Tafirout, R.; Taga, A.; Taiblum, N.; Takahashi, Y.; Takai, H.; Takashima, R.; Takeda, H.; Takeshita, T.; Talby, M.; Talyshev, A.; Tamsett, M. C.; Tanaka, J.; Tanaka, R.; Tanaka, S.; Tanaka, S.; Tanaka, Y.; Tani, K.; Tannoury, N.; Tappern, G. P.; Tapprogge, S.; Tardif, D.; Tarem, S.; Tarrade, F.; Tartarelli, G. F.; Tas, P.; Tasevsky, M.; Tassi, E.; Tatarkhanov, M.; Tayalati, Y.; Taylor, C.; Taylor, F. E.; Taylor, G. N.; Taylor, W.; Teixeira Dias Castanheira, M.; Teixeira-Dias, P.; Temming, K. K.; Ten Kate, H.; Teng, P. K.; Terada, S.; Terashi, K.; Terron, J.; Terwort, M.; Testa, M.; Teuscher, R. J.; Thadome, J.; Therhaag, J.; Theveneaux-Pelzer, T.; Thioye, M.; Thoma, S.; Thomas, J. P.; Thompson, E. N.; Thompson, P. D.; Thompson, P. D.; Thompson, A. S.; Thomson, E.; Thomson, M.; Thun, R. P.; Tic, T.; Tikhomirov, V. O.; Tikhonov, Y. A.; Timmermans, C. J. W. P.; Tipton, P.; Tique Aires Viegas, F. J.; Tisserant, S.; Tobias, J.; Toczek, B.; Todorov, T.; Todorova-Nova, S.; Toggerson, B.; Tojo, J.; Tokár, S.; Tokunaga, K.; Tokushuku, K.; Tollefson, K.; Tomoto, M.; Tompkins, L.; Toms, K.; Tong, G.; Tonoyan, A.; Topfel, C.; Topilin, N. D.; Torchiani, I.; Torrence, E.; Torró Pastor, E.; Toth, J.; Touchard, F.; Tovey, D. R.; Traynor, D.; Trefzger, T.; Treis, J.; Tremblet, L.; Tricoli, A.; Trigger, I. M.; Trincaz-Duvoid, S.; Trinh, T. N.; Tripiana, M. F.; Trischuk, W.; Trivedi, A.; Trocmé, B.; Troncon, C.; Trottier-McDonald, M.; Trzupek, A.; Tsarouchas, C.; Tseng, J. C.-L.; Tsiakiris, M.; Tsiareshka, P. V.; Tsionou, D.; Tsipolitis, G.; Tsiskaridze, V.; Tskhadadze, E. G.; Tsukerman, I. I.; Tsulaia, V.; Tsung, J.-W.; Tsuno, S.; Tsybychev, D.; Tua, A.; Tuggle, J. M.; Turala, M.; Turecek, D.; Turk Cakir, I.; Turlay, E.; Turra, R.; Tuts, P. M.; Tykhonov, A.; Tylmad, M.; Tyndel, M.; Tyrvainen, H.; Tzanakos, G.; Uchida, K.; Ueda, I.; Ueno, R.; Ugland, M.; Uhlenbrock, M.; Uhrmacher, M.; Ukegawa, F.; Unal, G.; Underwood, D. G.; Undrus, A.; Unel, G.; Unno, Y.; Urbaniec, D.; Urkovsky, E.; Urrejola, P.; Usai, G.; Uslenghi, M.; Vacavant, L.; Vacek, V.; Vachon, B.; Vahsen, S.; Valenta, J.; Valente, P.; Valentinetti, S.; Valkar, S.; Valladolid Gallego, E.; Vallecorsa, S.; Valls Ferrer, J. A.; van der Graaf, H.; van der Kraaij, E.; Van Der Leeuw, R.; van der Poel, E.; van der Ster, D.; Van Eijk, B.; van Eldik, N.; van Gemmeren, P.; van Kesteren, Z.; van Vulpen, I.; Vandelli, W.; Vandoni, G.; Vaniachine, A.; Vankov, P.; Vannucci, F.; Varela Rodriguez, F.; Vari, R.; Varnes, E. W.; Varouchas, D.; Vartapetian, A.; Varvell, K. E.; Vassilakopoulos, V. I.; Vazeille, F.; Vegni, G.; Veillet, J. J.; Vellidis, C.; Veloso, F.; Veness, R.; Veneziano, S.; Ventura, A.; Ventura, D.; Venturi, M.; Venturi, N.; Vercesi, V.; Verducci, M.; Verkerke, W.; Vermeulen, J. C.; Vest, A.; Vetterli, M. C.; Vichou, I.; Vickey, T.; Viehhauser, G. H. A.; Viel, S.; Villa, M.; Villaplana Perez, M.; Vilucchi, E.; Vincter, M. G.; Vinek, E.; Vinogradov, V. B.; Virchaux, M.; Viret, S.; Virzi, J.; Vitale, A.; Vitells, O.; Viti, M.; Vivarelli, I.; Vives Vaque, F.; Vlachos, S.; Vlasak, M.; Vlasov, N.; Vogel, A.; Vokac, P.; Volpi, G.; Volpi, M.; Volpini, G.; von der Schmitt, H.; von Loeben, J.; von Radziewski, H.; von Toerne, E.; Vorobel, V.; Vorobiev, A. P.; Vorwerk, V.; Vos, M.; Voss, R.; Voss, T. T.; Vossebeld, J. H.; Vranjes, N.; Vranjes Milosavljevic, M.; Vrba, V.; Vreeswijk, M.; Vu Anh, T.; Vuillermet, R.; Vukotic, I.; Wagner, W.; Wagner, P.; Wahlen, H.; Wakabayashi, J.; Walbersloh, J.; Walch, S.; Walder, J.; Walker, R.; Walkowiak, W.; Wall, R.; Waller, P.; Wang, C.; Wang, H.; Wang, H.; Wang, J.; Wang, J.; Wang, J. C.; Wang, R.; Wang, S. M.; Warburton, A.; Ward, C. P.; Warsinsky, M.; Watkins, P. M.; Watson, A. T.; Watson, M. F.; Watts, G.; Watts, S.; Waugh, A. T.; Waugh, B. M.; Weber, J.; Weber, M.; Weber, M. S.; Weber, P.; Weidberg, A. R.; Weigell, P.; Weingarten, J.; Weiser, C.; Wellenstein, H.; Wells, P. S.; Wen, M.; Wenaus, T.; Wendler, S.; Weng, Z.; Wengler, T.; Wenig, S.; Wermes, N.; Werner, M.; Werner, P.; Werth, M.; Wessels, M.; Weydert, C.; Whalen, K.; Wheeler-Ellis, S. J.; Whitaker, S. P.; White, A.; White, M. J.; White, S.; Whitehead, S. R.; Whiteson, D.; Whittington, D.; Wicek, F.; Wicke, D.; Wickens, F. J.; Wiedenmann, W.; Wielers, M.; Wienemann, P.; Wiglesworth, C.; Wiik, L. A. M.; Wijeratne, P. A.; Wildauer, A.; Wildt, M. A.; Wilhelm, I.; Wilkens, H. G.; Will, J. Z.; Williams, E.; Williams, H. H.; Willis, W.; Willocq, S.; Wilson, J. A.; Wilson, M. G.; Wilson, A.; Wingerter-Seez, I.; Winkelmann, S.; Winklmeier, F.; Wittgen, M.; Wolter, M. W.; Wolters, H.; Wooden, G.; Wosiek, B. K.; Wotschack, J.; Woudstra, M. J.; Wraight, K.; Wright, C.; Wrona, B.; Wu, S. L.; Wu, X.; Wu, Y.; Wulf, E.; Wunstorf, R.; Wynne, B. M.; Xaplanteris, L.; Xella, S.; Xie, S.; Xie, Y.; Xu, C.; Xu, D.; Xu, G.; Yabsley, B.; Yamada, M.; Yamamoto, A.; Yamamoto, K.; Yamamoto, S.; Yamamura, T.; Yamaoka, J.; Yamazaki, T.; Yamazaki, Y.; Yan, Z.; Yang, H.; Yang, U. K.; Yang, Y.; Yang, Y.; Yang, Z.; Yanush, S.; Yao, W.-M.; Yao, Y.; Yasu, Y.; Ybeles Smit, G. V.; Ye, J.; Ye, S.; Yilmaz, M.; Yoosoofmiya, R.; Yorita, K.; Yoshida, R.; Young, C.; Youssef, S.; Yu, D.; Yu, J.; Yu, J.; Yuan, L.; Yurkewicz, A.; Zaets, V. G.; Zaidan, R.; Zaitsev, A. M.; Zajacova, Z.; Zalite, Yo. K.; Zanello, L.; Zarzhitsky, P.; Zaytsev, A.; Zeitnitz, C.; Zeller, M.; Zemla, A.; Zendler, C.; Zenin, A. V.; Zenin, O.; Ženiš, T.; Zenonos, Z.; Zenz, S.; Zerwas, D.; Zevi della Porta, G.; Zhan, Z.; Zhang, D.; Zhang, H.; Zhang, J.; Zhang, X.; Zhang, Z.; Zhao, L.; Zhao, T.; Zhao, Z.; Zhemchugov, A.; Zheng, S.; Zhong, J.; Zhou, B.; Zhou, N.; Zhou, Y.; Zhu, C. G.; Zhu, H.; Zhu, Y.; Zhuang, X.; Zhuravlov, V.; Zieminska, D.; Zimmermann, R.; Zimmermann, S.; Zimmermann, S.; Ziolkowski, M.; Zitoun, R.; Živković, L.; Zmouchko, V. V.; Zobernig, G.; Zoccoli, A.; Zolnierowski, Y.; Zsenei, A.; zur Nedden, M.; Zutshi, V.; Zwalinski, L.

    2012-01-01

    Proton-proton collisions at sqrt{s}=7 TeV and heavy ion collisions at sqrt{s_{NN}}=2.76 TeV were produced by the LHC and recorded using the ATLAS experiment's trigger system in 2010. The LHC is designed with a maximum bunch crossing rate of 40 MHz and the ATLAS trigger system is designed to record approximately 200 of these per second. The trigger system selects events by rapidly identifying signatures of muon, electron, photon, tau lepton, jet, and B meson candidates, as well as using global event signatures, such as missing transverse energy. An overview of the ATLAS trigger system, the evolution of the system during 2010 and the performance of the trigger system components and selections based on the 2010 collision data are shown. A brief outline of plans for the trigger system in 2011 is presented.

  6. An Environmental Data Set for Vector-Borne Disease Modeling and Epidemiology

    PubMed Central

    Chabot-Couture, Guillaume; Nigmatulina, Karima; Eckhoff, Philip

    2014-01-01

    Understanding the environmental conditions of disease transmission is important in the study of vector-borne diseases. Low- and middle-income countries bear a significant portion of the disease burden; but data about weather conditions in those countries can be sparse and difficult to reconstruct. Here, we describe methods to assemble high-resolution gridded time series data sets of air temperature, relative humidity, land temperature, and rainfall for such areas; and we test these methods on the island of Madagascar. Air temperature and relative humidity were constructed using statistical interpolation of weather station measurements; the resulting median 95th percentile absolute errors were 2.75°C and 16.6%. Missing pixels from the MODIS11 remote sensing land temperature product were estimated using Fourier decomposition and time-series analysis; thus providing an alternative to the 8-day and 30-day aggregated products. The RFE 2.0 remote sensing rainfall estimator was characterized by comparing it with multiple interpolated rainfall products, and we observed significant differences in temporal and spatial heterogeneity relevant to vector-borne disease modeling. PMID:24755954

  7. Graphics Processing Units for HEP trigger systems

    NASA Astrophysics Data System (ADS)

    Ammendola, R.; Bauce, M.; Biagioni, A.; Chiozzi, S.; Cotta Ramusino, A.; Fantechi, R.; Fiorini, M.; Giagu, S.; Gianoli, A.; Lamanna, G.; Lonardo, A.; Messina, A.; Neri, I.; Paolucci, P. S.; Piandani, R.; Pontisso, L.; Rescigno, M.; Simula, F.; Sozzi, M.; Vicini, P.

    2016-07-01

    General-purpose computing on GPUs (Graphics Processing Units) is emerging as a new paradigm in several fields of science, although so far applications have been tailored to the specific strengths of such devices as accelerator in offline computation. With the steady reduction of GPU latencies, and the increase in link and memory throughput, the use of such devices for real-time applications in high-energy physics data acquisition and trigger systems is becoming ripe. We will discuss the use of online parallel computing on GPU for synchronous low level trigger, focusing on CERN NA62 experiment trigger system. The use of GPU in higher level trigger system is also briefly considered.

  8. DATA COLLECTION ON ENVIRONMENTAL MANAGEMENT OF ASTHMA

    EPA Science Inventory

    We are working with CDC to determine if we can add a module to one or more of their surveys which would provide information on awareness of and existing attitudes toward asthma and its environmental triggers, actions implemented and barriers to implementation encountered by adult...

  9. On near-source earthquake triggering

    USGS Publications Warehouse

    Parsons, T.; Velasco, A.A.

    2009-01-01

    When one earthquake triggers others nearby, what connects them? Two processes are observed: static stress change from fault offset and dynamic stress changes from passing seismic waves. In the near-source region (r ??? 50 km for M ??? 5 sources) both processes may be operating, and since both mechanisms are expected to raise earthquake rates, it is difficult to isolate them. We thus compare explosions with earthquakes because only earthquakes cause significant static stress changes. We find that large explosions at the Nevada Test Site do not trigger earthquakes at rates comparable to similar magnitude earthquakes. Surface waves are associated with regional and long-range dynamic triggering, but we note that surface waves with low enough frequency to penetrate to depths where most aftershocks of the 1992 M = 5.7 Little Skull Mountain main shock occurred (???12 km) would not have developed significant amplitude within a 50-km radius. We therefore focus on the best candidate phases to cause local dynamic triggering, direct waves that pass through observed near-source aftershock clusters. We examine these phases, which arrived at the nearest (200-270 km) broadband station before the surface wave train and could thus be isolated for study. Direct comparison of spectral amplitudes of presurface wave arrivals shows that M ??? 5 explosions and earthquakes deliver the same peak dynamic stresses into the near-source crust. We conclude that a static stress change model can readily explain observed aftershock patterns, whereas it is difficult to attribute near-source triggering to a dynamic process because of the dearth of aftershocks near large explosions.

  10. Triggers of self-conscious emotions in the sexually transmitted infection testing process

    PubMed Central

    2010-01-01

    Background Self-conscious emotions (shame, guilt and embarrassment) are part of many individuals' experiences of seeking STI testing. These emotions can have negative impacts on individuals' interpretations of the STI testing process, their willingness to seek treatment and their willingness to inform sexual partners in light of positive STI diagnoses. Because of these impacts, researchers have called for more work to be completed on the connections between shame, guilt, embarrassment and STI testing. We examine the specific events in the STI testing process that trigger self-conscious emotions in young adults who seek STI testing; and to understand what it is about these events that triggers these emotions. Semi-structured interviews with 30 adults (21 women, 9 men) in the Republic of Ireland. Findings Seven specific triggers of self-conscious emotions were identified. These were: having unprotected sex, associated with the initial reason for seeking STI testing; talking to partners and peers about the intention to seek STI testing; the experience of accessing STI testing facilities and sitting in clinic waiting rooms; negative interactions with healthcare professionals; receiving a positive diagnosis of an STI; having to notify sexual partners in light of a positive STI diagnosis; and accessing healthcare settings for treatment for an STI. Self-conscious emotions were triggered in each case by a perceived threat to respondents' social identities. Conclusion There are multiple triggers of self-conscious emotions in the STI testing process, ranging from the initial decision to seek testing, right through to the experience of accessing treatment. The role of self-conscious emotions needs to be considered in each component of service design from health promotion approaches, through facility layout to the training of all professionals involved in the STI testing process. PMID:20716339

  11. Earthquake Simulator Finds Tremor Triggers

    ScienceCinema

    Johnson, Paul

    2018-01-16

    Using a novel device that simulates earthquakes in a laboratory setting, a Los Alamos researcher has found that seismic waves-the sounds radiated from earthquakes-can induce earthquake aftershocks, often long after a quake has subsided. The research provides insight into how earthquakes may be triggered and how they recur. Los Alamos researcher Paul Johnson and colleague Chris Marone at Penn State have discovered how wave energy can be stored in certain types of granular materials-like the type found along certain fault lines across the globe-and how this stored energy can suddenly be released as an earthquake when hit by relatively small seismic waves far beyond the traditional “aftershock zone” of a main quake. Perhaps most surprising, researchers have found that the release of energy can occur minutes, hours, or even days after the sound waves pass; the cause of the delay remains a tantalizing mystery.

  12. Trigger design for a gamma ray detector of HIRFL-ETF

    NASA Astrophysics Data System (ADS)

    Du, Zhong-Wei; Su, Hong; Qian, Yi; Kong, Jie

    2013-10-01

    The Gamma Ray Array Detector (GRAD) is one subsystem of HIRFL-ETF (the External Target Facility (ETF) of the Heavy Ion Research Facility in Lanzhou (HIRFL)). It is capable of measuring the energy of gamma-rays with 1024 CsI scintillators in in-beam nuclear experiments. The GRAD trigger should select the valid events and reject the data from the scintillators which are not hit by the gamma-ray. The GRAD trigger has been developed based on the Field Programmable Gate Array (FPGAs) and PXI interface. It makes prompt trigger decisions to select valid events by processing the hit signals from the 1024 CsI scintillators. According to the physical requirements, the GRAD trigger module supplies 12-bit trigger information for the global trigger system of ETF and supplies a trigger signal for data acquisition (DAQ) system of GRAD. In addition, the GRAD trigger generates trigger data that are packed and transmitted to the host computer via PXI bus to be saved for off-line analysis. The trigger processing is implemented in the front-end electronics of GRAD and one FPGA of the GRAD trigger module. The logic of PXI transmission and reconfiguration is implemented in another FPGA of the GRAD trigger module. During the gamma-ray experiments, the GRAD trigger performs reliably and efficiently. The function of GRAD trigger is capable of satisfying the physical requirements.

  13. The dangers of being trigger-happy

    NASA Astrophysics Data System (ADS)

    Dale, J. E.; Haworth, T. J.; Bressert, E.

    2015-06-01

    We examine the evidence offered for triggered star formation against the backdrop provided by recent numerical simulations of feedback from massive stars at or below giant molecular cloud sizescales. We compile a catalogue of 67 observational papers, mostly published over the last decade, and examine the signposts most commonly used to infer the presence of triggered star formation. We then determine how well these signposts perform in a recent suite of hydrodynamic simulations of star formation including feedback from O-type stars performed by Dale et al. We find that none of the observational markers improve the chances of correctly identifying a given star as triggered by more than factors of 2 at most. This limits the fidelity of these techniques in interpreting star formation histories. We therefore urge caution in interpreting observations of star formation near feedback-driven structures in terms of triggering.

  14. Body-related pride in young adults: an exploration of the triggers, contexts, outcomes and attributions.

    PubMed

    Castonguay, Andree L; Gilchrist, Jenna D; Mack, Diane E; Sabiston, Catherine M

    2013-06-01

    This study explored body-related emotional experiences of pride in young adult males (n=138) and females (n=165). Data were collected using a relived emotion task and analyzed using inductive content analysis. Thirty-nine codes were identified and grouped into six categories (triggers, contexts, cognitive attributions, and affective, cognitive, and behavioral outcomes) for each of two themes (hubristic and authentic pride). Hubristic pride triggers included evaluating appearance/fitness as superior. Cognitions centered on feelings of superiority. Behaviors included strategies to show off. Triggers for authentic pride were personal improvements/maintenance in appearance and meeting or exceeding goals. Feeling accomplished was a cognitive outcome, and physical activity was a behavioral strategy. Contexts for the experience of both facets of pride primarily involved sports settings, swimming/beach, and clothes shopping. These findings provide theoretical support for models of pride as it applies to body image, and advances conceptual understanding of positive body image. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. Performance of the ATLAS Trigger System in 2010

    DOE PAGES

    Aad, G.; Abbott, B.; Abdallah, J.; ...

    2012-01-03

    Proton-proton collisions atmore » $$\\sqrt{s}$$ = 7 TeV and heavy ion collisions at $$\\sqrt{s}$$$_ {NN}$$ = 2.76 TeV were produced by the LHC and recorded using the ATLAS experiment's trigger system in 2010. The LHC is designed with a maximum bunch crossing rate of 40 MHz and the ATLAS trigger system is designed to record approximately 200 of these per second. The trigger system selects events by rapidly identifying signatures of muon, electron, photon, tau lepton, jet, and B meson candidates, as well as using global event signatures, such as missing transverse energy. An overview of the ATLAS trigger system, the evolution of the system during 2010 and the performance of the trigger system components and selections based on the 2010 collision data are shown. In conclusion, a brief outline of plans for the trigger system in 2011 is presented.« less

  16. Flower abscission in Vitis vinifera L. triggered by gibberellic acid and shade discloses differences in the underlying metabolic pathways

    PubMed Central

    Domingos, Sara; Scafidi, Pietro; Cardoso, Vania; Leitao, Antonio E.; Di Lorenzo, Rosario; Oliveira, Cristina M.; Goulao, Luis F.

    2015-01-01

    Understanding abscission is both a biological and an agronomic challenge. Flower abscission induced independently by shade and gibberellic acid (GAc) sprays was monitored in grapevine (Vitis vinifera L.) growing under a soilless greenhouse system during two seasonal growing conditions, in an early and late production cycle. Physiological and metabolic changes triggered by each of the two distinct stimuli were determined. Environmental conditions exerted a significant effect on fruit set as showed by the higher natural drop rate recorded in the late production cycle with respect to the early cycle. Shade and GAc treatments increased the percentage of flower drop compared to the control, and at a similar degree, during the late production cycle. The reduction of leaf gas exchanges under shade conditions was not observed in GAc treated vines. The metabolic profile assessed in samples collected during the late cycle differently affected primary and secondary metabolisms and showed that most of the treatment-resulting variations occurred in opposite trends in inflorescences unbalanced in either hormonal or energy deficit abscission-inducing signals. Particularly concerning carbohydrates metabolism, sucrose, glucose, tricarboxylic acid metabolites and intermediates of the raffinose family oligosaccharides pathway were lower in shaded and higher in GAc samples. Altered oxidative stress remediation mechanisms and indolacetic acid (IAA) concentration were identified as abscission signatures common to both stimuli. According to the global analysis performed, we report that grape flower abscission mechanisms triggered by GAc application and C-starvation are not based on the same metabolic pathways. PMID:26157448

  17. Triggering on New Physics with the CMS Detector

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bose, Tulika

    The BU CMS group led by PI Tulika Bose has made several significant contributions to the CMS trigger and to the analysis of the data collected by the CMS experiment. Group members have played a leading role in the optimization of trigger algorithms, the development of trigger menus, and the online operation of the CMS High-Level Trigger. The group’s data analysis projects have concentrated on a broad spectrum of topics that take full advantage of their strengths in jets and calorimetry, trigger, lepton identification as well as their considerable experience in hadron collider physics. Their publications cover several searches formore » new heavy gauge bosons, vector-like quarks as well as diboson resonances.« less

  18. Probabilistic clustering of rainfall condition for landslide triggering

    NASA Astrophysics Data System (ADS)

    Rossi, Mauro; Luciani, Silvia; Cesare Mondini, Alessandro; Kirschbaum, Dalia; Valigi, Daniela; Guzzetti, Fausto

    2013-04-01

    Landslides are widespread natural and man made phenomena. They are triggered by earthquakes, rapid snow melting, human activities, but mostly by typhoons and intense or prolonged rainfall precipitations. In Italy mostly they are triggered by intense precipitation. The prediction of landslide triggered by rainfall precipitations over large areas is commonly based on the exploitation of empirical models. Empirical landslide rainfall thresholds are used to identify rainfall conditions for the possible landslide initiation. It's common practice to define rainfall thresholds by assuming a power law lower boundary in the rainfall intensity-duration or cumulative rainfall-duration space above which landslide can occur. The boundary is defined considering rainfall conditions associated to landslide phenomena using heuristic approaches, and doesn't consider rainfall events not causing landslides. Here we present a new fully automatic method to identify the probability of landslide occurrence associated to rainfall conditions characterized by measures of intensity or cumulative rainfall and rainfall duration. The method splits the rainfall events of the past in two groups: a group of events causing landslides and its complementary, then estimate their probabilistic distributions. Next, the probabilistic membership of the new event to one of the two clusters is estimated. The method doesn't assume a priori any threshold model, but simple exploits the real empirical distribution of rainfall events. The approach was applied in the Umbria region, Central Italy, where a catalogue of landslide timing, were obtained through the search of chronicles, blogs and other source of information in the period 2002-2012. The approach was tested using rain gauge measures and satellite rainfall estimates (NASA TRMM-v6), allowing in both cases the identification of the rainfall condition triggering landslides in the region. Compared to the other existing threshold definition methods, the prosed

  19. Delta 9 -tetrahydrocannabinol and ethanol: differential effects on sympathetic activity in differing environmental setting.

    PubMed

    Ng, L K; Lamprecht, F; Williams, R B; Kopin, I J

    1973-06-29

    Serum dopamine beta-hydroxylase activity, a useful biochemical index of peripheral sympathetic nervous activity, was measured in rats treated with Delta(9)-tetrahydrocannabinol or ethanol or both substances. After 7 days of treatment with either substance, serum dopamine beta-hydroxylase activity decreased significantly. Combined treatment with both agents enhanced the effects of each given alone. In rats subjected to immobilization stress, treatment with Delta(9)- tetrahydrocannabinol appeared to potentiate the stress-induced increase in serum enzyme activity. Treatment with ethanol, with or without Delta(9)-tetrahydrocannabinol, effectively blocked this increase in enzyme activity. These results show that both substances have significant effects on the sympathetic nervous system which are critically influenced by environmental setting.

  20. A hypothesis for delayed dynamic earthquake triggering

    USGS Publications Warehouse

    Parsons, T.

    2005-01-01

    It's uncertain whether more near-field earthquakes are triggered by static or dynamic stress changes. This ratio matters because static earthquake interactions are increasingly incorporated into probabilistic forecasts. Recent studies were unable to demonstrate all predictions from the static-stress-change hypothesis, particularly seismicity rate reductions. However, current dynamic stress change hypotheses do not explain delayed earthquake triggering and Omori's law. Here I show numerically that if seismic waves can alter some frictional contacts in neighboring fault zones, then dynamic triggering might cause delayed triggering and an Omori-law response. The hypothesis depends on faults following a rate/state friction law, and on seismic waves changing the mean critical slip distance (Dc) at nucleation zones.

  1. Education in Environmental Chemistry: Setting the Agenda and Recommending Action

    ERIC Educational Resources Information Center

    Zoller, Uri

    2005-01-01

    The effective utilization of Education in Environmental Chemistry (EEC) in addressing global and societal environmental problems requires integration between educational, technical, financial, ethical and societal considerations. An interdisciplinary approach is fundamental to efforts to achieve long-term solutions.

  2. Perceived Triggers of Asthma: Key to Symptom Perception and Management

    PubMed Central

    Janssens, Thomas; Ritz, Thomas

    2013-01-01

    Adequate asthma management depends on an accurate identification of asthma triggers. A review of the literature on trigger perception in asthma shows that individuals vary in their perception of asthma triggers and that the correlation between self-reported asthma triggers and allergy tests is only modest. In this paper, we provide an overview of psychological mechanisms involved in the process of asthma triggers identification. We identify sources of errors in trigger identification and targets for behavioral interventions that aim to improve the accuracy of asthma trigger identification and thereby enhance asthma control. PMID:23957335

  3. The Seattle-King County Healthy Homes Project: A Randomized, Controlled Trial of a Community Health Worker Intervention to Decrease Exposure to Indoor Asthma Triggers

    PubMed Central

    Krieger, James W.; Takaro, Tim K.; Song, Lin; Weaver, Marcia

    2005-01-01

    Objectives. We assessed the effectiveness of a community health worker intervention focused on reducing exposure to indoor asthma triggers. Methods. We conducted a randomized controlled trial with 1-year follow-up among 274 low-income households containing a child aged 4–12 years who had asthma. Community health workers provided in-home environmental assessments, education, support for behavior change, and resources. Participants were assigned to either a high-intensity group receiving 7 visits and a full set of resources or a low-intensity group receiving a single visit and limited resources. Results. The high-intensity group improved significantly more than the low-intensity group in its pediatric asthma caregiver quality-of-life score (P=.005) and asthma-related urgent health services use (P=.026). Asthma symptom days declined more in the high-intensity group, although the across-group difference did not reach statistical significance (P= .138). Participant actions to reduce triggers generally increased in the high-intensity group. The projected 4-year net savings per participant among the high-intensity group relative to the low-intensity group were $189–$721. Conclusions. Community health workers reduced asthma symptom days and urgent health services use while improving caregiver quality-of-life score. Improvement was greater with a higher-intensity intervention. PMID:15798126

  4. Toward a rational understanding of migraine trigger factors.

    PubMed

    Martin, V T; Behbehani, M M

    2001-07-01

    The typical migraine patient is exposed to a myriad of migraine triggers on a daily basis. These triggers potentially can act at various sites within the cerebral vasculature and the central nervous system to promote the development of migraine headache. The challenge to the physician is in the identification and avoidance of migraine trigger factors within patients suffering from migraine headache. Only through a rational approach to migraine trigger factors can physicians develop an appropriate treatment strategy for migraine patients.

  5. A plant effector-triggered immunity signaling sector is inhibited by pattern-triggered immunity.

    PubMed

    Hatsugai, Noriyuki; Igarashi, Daisuke; Mase, Keisuke; Lu, You; Tsuda, Yayoi; Chakravarthy, Suma; Wei, Hai-Lei; Foley, Joseph W; Collmer, Alan; Glazebrook, Jane; Katagiri, Fumiaki

    2017-09-15

    Since signaling machineries for two modes of plant-induced immunity, pattern-triggered immunity (PTI) and effector-triggered immunity (ETI), extensively overlap, PTI and ETI signaling likely interact. In an Arabidopsis quadruple mutant, in which four major sectors of the signaling network, jasmonate, ethylene, PAD4, and salicylate, are disabled, the hypersensitive response (HR) typical of ETI is abolished when the Pseudomonas syringae effector AvrRpt2 is bacterially delivered but is intact when AvrRpt2 is directly expressed in planta These observations led us to discovery of a network-buffered signaling mechanism that mediates HR signaling and is strongly inhibited by PTI signaling. We named this mechanism the ETI-Mediating and PTI-Inhibited Sector (EMPIS). The signaling kinetics of EMPIS explain apparently different plant genetic requirements for ETI triggered by different effectors without postulating different signaling machineries. The properties of EMPIS suggest that information about efficacy of the early immune response is fed back to the immune signaling network, modulating its activity and limiting the fitness cost of unnecessary immune responses. © 2017 The Authors.

  6. Fast Plasma Investigation for MMS: Simulation of the Burst Triggering System

    NASA Technical Reports Server (NTRS)

    Barrie, A. C.; Dorelli, J. C.; Winkert, G. E.; Lobell, J. V.; Holland, M. P.; Adrian, M. L.; Pollock, C. J.

    2011-01-01

    The Magnetospheric Multiscale (MMS) mission will study small-scale reconnection structures and their rapid motions from closely spaced platforms using instruments capable of high angular, energy, and time resolution measurements. To meet these requirements, the Fast Plasma Instrument (FPI) consists of eight (8) identical half top-hat electron sensors and eight (8) identical ion sensors and an Instrument Data Processing Unit (IDPU). The sensors (electron or ion) are grouped into pairs whose 6 degree x 180 degree fields-of-view (FOV) are set 90 degrees apart. Each sensor is equipped with electrostatic aperture steering to allow the sensor to scan a 45 degree x 180 degree fan about the its nominal viewing (0 deflection) direction. Each pair of sensors, known as the Dual Electron Spectrometer (DES) and the Dual Ion Spectrometer (DIS), occupies a quadrant on the MMS spacecraft and the combination of the eight electron/ion sensors, employing aperture steering, image the full-sky every 30-ms (electrons) and 150-ms (ions), respectively. To probe the diffusion regions of reconnection, the highest temporal/spatial resolution mode of FPI results in the DES complement of a given spacecraft generating 6.5-Mb (raised dot) per second of electron data while the DIS generates 1.1-Mb (raised dot) per second of ion data yielding an FPI total data rate of 6.6-Mb (raised dot) per second. The FPI electron/ion data is collected by the IDPU then transmitted to the Central Data Instrument Processor (CIDP) on the spacecraft for science interest ranking. Only data sequences that contain the greatest amount of temporal/spatial structure will be intelligently down-linked by the spacecraft. This requires a data ranking process known as the burst trigger system. The burst trigger system uses pseudo physical quantities to approximate the local plasma environments. As each pseudo quantity will have a different value, a set of two scaling factors is employed for each pseudo term. These pseudo

  7. The Tidal Triggering of Earthquakes Under Certain Circumstances

    NASA Astrophysics Data System (ADS)

    Goodacre, A. K.

    2004-05-01

    Although it would be lunacy to claim that all earthquakes are triggered by the motions of the Moon and Sun, there are certain circumstances where these celestial bodies might play a role. This would especially be the case where pre-existing, nearly vertical zones of weakness are present and, hence, the solid-earth tidal stresses would have maximum effect. I have investigated two possible areas: i) the Charlevoix seismic region of Québec along the St. Lawrence River and )ii the San Andreas and Calaveras Faults in California. In the Charlevoix region there a few suites of earthquakes, recognized by Maurice Lamontagne and lying mainly beneath or at the edge of the St. Lawrence River, in which the events in each suite occur in a relatively small volume of rock and produce similar waveforms characteristic of the particular location involved. This sort of repeated rupturing suggests the possibility of triggering by solid-earth and/or marine tides. In one sequence of 9 events (2 of which are left out of the analysis because they are aftershocks) it appears that there is only about one chance in ten that this sequence occurred at random. Unfortunately, there are no fault-plane solutions for any events in this particular set of earthquakes and so it is difficult to comment on failure mechanisms. However, in the case of the Calaveras and San Andreas Faults of California where fault-plane solutions are often available, if we restrict our attention to the larger, strike-slip earthquakes, it appears that lunar and solar tides (both solid-earth and marine) do, in fact, play a role in the timing of these events and the triggering mechanism may involve the amount of incremental normal stress acting upon these two faults.

  8. Aftershocks and triggering processes in rock fracture

    NASA Astrophysics Data System (ADS)

    Davidsen, J.; Kwiatek, G.; Goebel, T.; Stanchits, S. A.; Dresen, G.

    2017-12-01

    One of the hallmarks of our understanding of seismicity in nature is the importance of triggering processes, which makes the forecasting of seismic activity feasible. These triggering processes by which one earthquake induces (dynamic or static) stress changes leading to potentially multiple other earthquakes are at the core relaxation processes. A specic example of triggering are aftershocks following a large earthquake, which have been observed to follow certain empirical relationships such as the Omori-Utsu relation. Such an empirical relation should arise from the underlying microscopic dynamics of the involved physical processes but the exact connection remains to be established. Simple explanations have been proposed but their general applicability is unclear. Many explanations involve the picture of an earthquake as a purely frictional sliding event. Here, we present experimental evidence that these empirical relationships are not limited to frictional processes but also arise in fracture zone formation and are mostly related to compaction-type events. Our analysis is based on tri-axial compression experiments under constant displacement rate on sandstone and granite samples using spatially located acoustic emission events and their focal mechanisms. More importantly, we show that event-event triggering plays an important role in the presence of large-scale or macrocopic imperfections while such triggering is basically absent if no signicant imperfections are present. We also show that spatial localization and an increase in activity rates close to failure do not necessarily imply triggering behavior associated with aftershocks. Only if a macroscopic crack is formed and its propagation remains subcritical do we observe significant triggering.

  9. Trigger and Readout System for the Ashra-1 Detector

    NASA Astrophysics Data System (ADS)

    Aita, Y.; Aoki, T.; Asaoka, Y.; Morimoto, Y.; Motz, H. M.; Sasaki, M.; Abiko, C.; Kanokohata, C.; Ogawa, S.; Shibuya, H.; Takada, T.; Kimura, T.; Learned, J. G.; Matsuno, S.; Kuze, S.; Binder, P. M.; Goldman, J.; Sugiyama, N.; Watanabe, Y.

    Highly sophisticated trigger and readout system has been developed for All-sky Survey High Resolution Air-shower (Ashra) detector. Ashra-1 detector has 42 degree diameter field of view. Detection of Cherenkov and fluorescence light from large background in the large field of view requires finely segmented and high speed trigger and readout system. The system is composed of optical fiber image transmission system, 64 × 64 channel trigger sensor and FPGA based trigger logic processor. The system typically processes the image within 10 to 30 ns and opens the shutter on the fine CMOS sensor. 64 × 64 coarse split image is transferred via 64 × 64 precisely aligned optical fiber bundle to a photon sensor. Current signals from the photon sensor are discriminated by custom made trigger amplifiers. FPGA based processor processes 64 × 64 hit pattern and correspondent partial area of the fine image is acquired. Commissioning earth skimming tau neutrino observational search was carried out with this trigger system. In addition to the geometrical advantage of the Ashra observational site, the excellent tau shower axis measurement based on the fine imaging and the night sky background rejection based on the fine and fast imaging allow zero background tau shower search. Adoption of the optical fiber bundle and trigger LSI realized 4k channel trigger system cheaply. Detectability of tau shower is also confirmed by simultaneously observed Cherenkov air shower. Reduction of the trigger threshold appears to enhance the effective area especially in PeV tau neutrino energy region. New two dimensional trigger LSI was introduced and the trigger threshold was lowered. New calibration system of the trigger system was recently developed and introduced to the Ashra detector

  10. Dynamic stresses, coulomb failure, and remote triggering: corrected

    USGS Publications Warehouse

    Hill, David P.

    2012-01-01

    Dynamic stresses associated with crustal surface waves with 15–30 s periods and peak amplitudes <1  MPa are capable of triggering seismicity at sites remote from the generating mainshock under appropriate conditions. Coulomb failure models based on a frictional strength threshold offer one explanation for instances of rapid‐onset triggered seismicity that develop during the surface‐wave peak dynamic stressing. Evaluation of the triggering potential of surface‐wave dynamic stresses acting on critically stressed faults using a Mohr’s circle representation together with the Coulomb failure criteria indicates that Love waves should have a higher triggering potential than Rayleigh waves for most fault orientations and wave incidence angles. That (1) the onset of triggered seismicity often appears to begin during the Rayleigh wave rather than the earlier arriving Love wave, and (2) Love‐wave amplitudes typically exceed those for Rayleigh waves suggests that the explanation for rapid‐onset dynamic triggering may not reside solely with a simple static‐threshold friction mode. The results also indicate that normal faults should be more susceptible to dynamic triggering by 20‐s Rayleigh‐wave stresses than thrust faults in the shallow seismogenic crust (<10  km) while the advantage tips in favor of reverse faults greater depths. This transition depth scales with wavelength and coincides roughly with the transition from retrograde‐to‐prograde particle motion. Locally elevated pore pressures may have a role in the observed prevalence of dynamic triggering in extensional regimes and geothermal/volcanic systems. The result is consistent with the apparent elevated susceptibility of extensional or transtensional tectonic regimes to remote triggering by Rayleigh‐wave dynamic stresses than compressional or transpressional regimes.

  11. Revisiting Pneumatic Nail Gun Trigger Recommendations

    PubMed Central

    Albers, James; Lipscomb, Hester; Hudock, Stephen; Dement, John; Evanoff, Bradley; Fullen, Mark; Gillen, Matt; Kaskutas, Vicki; Nolan, James; Patterson, Dennis; Platner, James; Pompeii, Lisa; Schoenfisch, Ashley

    2015-01-01

    Summary Use of a pneumatic nail gun with a sequential actuation trigger (SAT) significantly diminishes the risk for acute traumatic injury compared to use of a contact actuation trigger (CAT) nail gun. A theoretically-based increased risk of work-related musculoskeletal disorders from use of a SAT nail gun, relative to CAT, appears unlikely and remains unproven. Based on current knowledge, the use of CAT nail guns cannot be justified as a safe alternative to SAT nail guns. This letter provides a perspective of ergonomists and occupational safety researchers recommending the use of the sequential actuation trigger for all nail gun tasks in the construction industry. PMID:26366020

  12. Revisiting Pneumatic Nail Gun Trigger Recommendations.

    PubMed

    Albers, James; Lowe, Brian; Lipscomb, Hester; Hudock, Stephen; Dement, John; Evanoff, Bradley; Fullen, Mark; Gillen, Matt; Kaskutas, Vicki; Nolan, James; Patterson, Dennis; Platner, James; Pompeii, Lisa; Schoenfisch, Ashley

    2015-03-01

    Use of a pneumatic nail gun with a sequential actuation trigger (SAT) significantly diminishes the risk for acute traumatic injury compared to use of a contact actuation trigger (CAT) nail gun. A theoretically-based increased risk of work-related musculoskeletal disorders from use of a SAT nail gun, relative to CAT, appears unlikely and remains unproven. Based on current knowledge, the use of CAT nail guns cannot be justified as a safe alternative to SAT nail guns. This letter provides a perspective of ergonomists and occupational safety researchers recommending the use of the sequential actuation trigger for all nail gun tasks in the construction industry.

  13. Dynamic Triggering around Fangshan Pluton near Beijing,China

    NASA Astrophysics Data System (ADS)

    Wang, W.; Gong, X.; Peng, Z.; Chen, Q.; Wu, C.

    2011-12-01

    Fangshan Pluton lies at SW of Beijing City and is formed at about 133-128Ma. The Pluton is surrounded by the NNE-trending Taihang mountain in the west as an "C" shape, and is in conjunction with the Northern China Plain along the Baobashan fault in the east. This region currently does not have abundant background seismicity, but previous studies (Peng et al., 2010, Wu et al. 2011) have shown that at least 4 major earthquakes in East Asia have triggered clear seismic events in this region. To further understand the dynamic triggering mechanism and improve the station coverage, we deployed the first batch temporal seismic array with 5 stations from 12/2008 to 7/2010 and the second batch with 11 stations around this area since 12/2010. Our temporary deployment was fortunate to capture the triggered seismicity following the 2011 Mw9.0 Tohoku-Oki, Japan, earthquake sequence. In this study, we use seismic data recorded by the permanent stations in the Capital Circle seismic network and our temporary deployment to investigate triggered seismicity following the 2010 Mw8.8 Chile earthquake and the Tohoku-Oki earthquake sequence. As was done before, we identify triggered earthquakes as impulsive seismic arrivals with clear P- and S-waves in 5 Hz high-pass-filtered three-component velocity seismograms and recorded by at least 3 stations. Most triggered earthquakes coincide with the large-amplitude Rayleigh waves. For the Tohoku-Oki case, we identify one weak event during the P-wave of the mainshock, and delayed triggering following the large-amplitude surface waves. In addition, triggered earthquakes can be seen in the Mw7.3 foreshock and mainshock of Tohoku earthquake, but not in aftershocks with 2 Mw>7.5 earthquakes in the following two months. These events mainly occurred at southwestern and western boundary region of the Pluton and are shallower (<5km) than normal earthquakes, which is similar to previous studies. Considering the abundant solution cavities and syncline

  14. Acoustically induced slip in sheared granular layers: Application to dynamic earthquake triggering: TRIGGERED SLIP IN SHEARED GRANULAR GOUGE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ferdowsi, Behrooz; Griffa, Michele; Guyer, Robert A.

    A fundamental mystery in earthquake physics is “how can an earthquake be triggered by distant seismic sources?” We use discrete element method simulations of a granular layer, during stick slip, that is subject to transient vibrational excitation to gain further insight into the physics of dynamic earthquake triggering. We also observe delayed triggering of slip in the granular gouge, using Coulomb friction law for grains interaction. We find that at a critical vibrational amplitude (strain) there is an abrupt transition from negligible time-advanced slip (clock advance) to full clock advance; i.e., transient vibration and triggered slip are simultaneous. Moreover, themore » critical strain is of order 10 -6, similar to observations in the laboratory and in Earth. The transition is related to frictional weakening of the granular layer due to a dramatic decrease in coordination number and the weakening of the contact force network. Associated with this frictional weakening is a pronounced decrease in the elastic modulus of the layer. The study has important implications for mechanisms of triggered earthquakes and induced seismic events and points out the underlying processes in response of the fault gouge to dynamic transient stresses.« less

  15. Acoustically induced slip in sheared granular layers: Application to dynamic earthquake triggering: TRIGGERED SLIP IN SHEARED GRANULAR GOUGE

    DOE PAGES

    Ferdowsi, Behrooz; Griffa, Michele; Guyer, Robert A.; ...

    2015-11-19

    A fundamental mystery in earthquake physics is “how can an earthquake be triggered by distant seismic sources?” We use discrete element method simulations of a granular layer, during stick slip, that is subject to transient vibrational excitation to gain further insight into the physics of dynamic earthquake triggering. We also observe delayed triggering of slip in the granular gouge, using Coulomb friction law for grains interaction. We find that at a critical vibrational amplitude (strain) there is an abrupt transition from negligible time-advanced slip (clock advance) to full clock advance; i.e., transient vibration and triggered slip are simultaneous. Moreover, themore » critical strain is of order 10 -6, similar to observations in the laboratory and in Earth. The transition is related to frictional weakening of the granular layer due to a dramatic decrease in coordination number and the weakening of the contact force network. Associated with this frictional weakening is a pronounced decrease in the elastic modulus of the layer. The study has important implications for mechanisms of triggered earthquakes and induced seismic events and points out the underlying processes in response of the fault gouge to dynamic transient stresses.« less

  16. Slope movements triggered by heavy rainfall, November 3–5, 1985, in Virginia and West Virginia, U.S.A.

    USGS Publications Warehouse

    Jacobson, Robert B.; Cron, Elizabeth D.; McGeehin, John P.

    1989-01-01

    Study of slope movements triggered by the storm of November 3–5, 1985, in the central Appalachian Mountains, U.S.A., has helped to define the meteorologic conditions leading to slope movements and the relative importance of land cover, bedrock, surficial geology, and geomorphology in slope movement location. This long-duration rainfall at moderate intensities triggered more than 1,000 slope movements in a 1,040-km2 study area. Most were shallow slips and slip-flows in thin colluvium and residuum on shale slopes. Locations of these failures were sensitive to land cover and slope aspect but were relatively insensitive to topographic setting. A few shallow slope movements were triggered by the same rainfall on interbedded limestone, shale, and sandstone. Several large debris slide-avalanches were triggered in sandstone regolith high on ridges in areas of the highest measured rainfall. Most of these sites were on slopes that dip 30 to 35° and lie parallel to bedding planes, presumably the sites of least stability.

  17. Boosting standard order sets utilization through clinical decision support.

    PubMed

    Li, Haomin; Zhang, Yinsheng; Cheng, Haixia; Lu, Xudong; Duan, Huilong

    2013-01-01

    Well-designed standard order sets have the potential to integrate and coordinate care by communicating best practices through multiple disciplines, levels of care, and services. However, there are several challenges which certainly affected the benefits expected from standard order sets. To boost standard order sets utilization, a problem-oriented knowledge delivery solution was proposed in this study to facilitate access of standard order sets and evaluation of its treatment effect. In this solution, standard order sets were created along with diagnostic rule sets which can trigger a CDS-based reminder to help clinician quickly discovery hidden clinical problems and corresponding standard order sets during ordering. Those rule set also provide indicators for targeted evaluation of standard order sets during treatment. A prototype system was developed based on this solution and will be presented at Medinfo 2013.

  18. Environmental testing of a diode-laser-pumped Nd:YAG laser and a set of diode-laser-arrays

    NASA Technical Reports Server (NTRS)

    Hemmati, H.; Lesh, J. R.

    1989-01-01

    Results of the environmental test of a compact, rigid and lightweight diode-laser-pumped Nd:YAG laser module are discussed. All optical elements are bonded onto the module using space applicable epoxy, and two 200 mW diode laser arrays for pump sources are used to achieve 126 mW of CW output with about 7 percent electrical-to-optical conversion efficiency. This laser assembly and a set of 20 semiconductor diode laser arrays were environmentally tested by being subjected to vibrational and thermal conditions similar to those experienced during launch of the Space Shuttle, and both performed well. Nevertheless, some damage to the laser front facet in diode lasers was observed. Significant degradation was observed only on lasers which performed poorly in the life test. Improvements in the reliability of the Nd:YAG laser are suggested.

  19. Note: Triggering behavior of a vacuum arc plasma source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lan, C. H., E-mail: lanchaohui@163.com; Long, J. D.; Zheng, L.

    2016-08-15

    Axial symmetry of discharge is very important for application of vacuum arc plasma. It is discovered that the triggering method is a significant factor that would influence the symmetry of arc discharge at the final stable stage. Using high-speed multiframe photography, the transition processes from cathode-trigger discharge to cathode-anode discharge were observed. It is shown that the performances of the two triggering methods investigated are quite different. Arc discharge triggered by independent electric source can be stabilized at the center of anode grid, but it is difficult to achieve such good symmetry through resistance triggering. It is also found thatmore » the triggering process is highly correlated to the behavior of emitted electrons.« less

  20. The twilight zone: ambient light levels trigger activity in primitive ants.

    PubMed

    Narendra, Ajay; Reid, Samuel F; Hemmi, Jan M

    2010-05-22

    Many animals become active during twilight, a narrow time window where the properties of the visual environment are dramatically different from both day and night. Despite the fact that many animals including mammals, reptiles, birds and insects become active in this specific temporal niche, we do not know what cues trigger this activity. To identify the onset of specific temporal niches, animals could anticipate the timing of regular events or directly measure environmental variables. We show that the Australian bull ant, Myrmecia pyriformis, starts foraging only during evening twilight throughout the year. The onset occurs neither at a specific temperature nor at a specific time relative to sunset, but at a specific ambient light intensity. Foraging onset occurs later when light intensities at sunset are brighter than normal or earlier when light intensities at sunset are darker than normal. By modifying ambient light intensity experimentally, we provide clear evidence that ants indeed measure light levels and do not rely on an internal rhythm to begin foraging. We suggest that the reason for restricting the foraging onset to twilight and measuring light intensity to trigger activity is to optimize the trade-off between predation risk and ease of navigation.

  1. Coupled dynamics of body mass and population growth in response to environmental change.

    PubMed

    Ozgul, Arpat; Childs, Dylan Z; Oli, Madan K; Armitage, Kenneth B; Blumstein, Daniel T; Olson, Lucretia E; Tuljapurkar, Shripad; Coulson, Tim

    2010-07-22

    Environmental change has altered the phenology, morphological traits and population dynamics of many species. However, the links underlying these joint responses remain largely unknown owing to a paucity of long-term data and the lack of an appropriate analytical framework. Here we investigate the link between phenotypic and demographic responses to environmental change using a new methodology and a long-term (1976-2008) data set from a hibernating mammal (the yellow-bellied marmot) inhabiting a dynamic subalpine habitat. We demonstrate how earlier emergence from hibernation and earlier weaning of young has led to a longer growing season and larger body masses before hibernation. The resulting shift in both the phenotype and the relationship between phenotype and fitness components led to a decline in adult mortality, which in turn triggered an abrupt increase in population size in recent years. Direct and trait-mediated effects of environmental change made comparable contributions to the observed marked increase in population growth. Our results help explain how a shift in phenology can cause simultaneous phenotypic and demographic changes, and highlight the need for a theory integrating ecological and evolutionary dynamics in stochastic environments.

  2. Effector-triggered defence against apoplastic fungal pathogens

    PubMed Central

    Stotz, Henrik U.; Mitrousia, Georgia K.; de Wit, Pierre J.G.M.; Fitt, Bruce D.L.

    2014-01-01

    R gene-mediated host resistance against apoplastic fungal pathogens is not adequately explained by the terms pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) or effector-triggered immunity (ETI). Therefore, it is proposed that this type of resistance is termed ‘effector-triggered defence’ (ETD). Unlike PTI and ETI, ETD is mediated by R genes encoding cell surface-localised receptor-like proteins (RLPs) that engage the receptor-like kinase SOBIR1. In contrast to this extracellular recognition, ETI is initiated by intracellular detection of pathogen effectors. ETI is usually associated with fast, hypersensitive host cell death, whereas ETD often triggers host cell death only after an elapsed period of endophytic pathogen growth. In this opinion, we focus on ETD responses against foliar fungal pathogens of crops. PMID:24856287

  3. Analysis of the Environmental Impact of Insulin Infusion Sets Based on Loss of Resources with Waste

    PubMed Central

    Pfützner, Andreas; Musholt, Petra B; Malmgren-Hansen, Bjoern; Nilsson, Nils H; Forst, Thomas

    2011-01-01

    Insulin pump therapy [continuous subcutaneous insulin infusion (CSII)] requires regular change of infusion sets every 2-3 days in order to minimize the risk of skin irritations or other adverse events. This has been discussed to be a potential burden to the environment. The purpose of this analysis was to perform an environmental assessment of insulin pump infusion sets based on loss of resources occurring during incineration of the discarded products and by means of a lifecycle concept used to weight a material in relation to its rareness on earth and its consumption. In addition to five infusion sets (Inset30, InsetII, Comfort, Quick-set, and Cleo), a patch pump (Omnipod) was also included in this analysis. The annual loss in waste of the so called “person reserve” of 3 days of catheter use was compared with daily consumption of a cup of coffee in a disposable paper cup and to a soft drink in an aluminum can. The weight-based loss in resources through waste for the infusion sets (except for Cleo) corresponded to 70-200% of the loss of resources for a coffee cup (Cleo, 320%; Omnipod, 1,821,600%) and to 1-3% of the loss from an aluminum soft drink can (Cleo, 5%; Omnipod, 31,200%). The loss or resources by use of infusion sets used in insulin pump therapy appears to be low and is similar to the burden induced by the uptake of one cup of coffee per day. The loss or resources with regular CSII is considerably lower than the loss or resources induced by patch pumps. PMID:21880223

  4. Investigating on the Differences between Triggered and Background Seismicity in Italy and Southern California.

    NASA Astrophysics Data System (ADS)

    Stallone, A.; Marzocchi, W.

    2017-12-01

    Earthquake occurrence may be approximated by a multidimensional Poisson clustering process, where each point of the Poisson process is replaced by a cluster of points, the latter corresponding to the well-known aftershock sequence (triggered events). Earthquake clusters and their parents are assumed to occur according to a Poisson process at a constant temporal rate proportional to the tectonic strain rate, while events within a cluster are modeled as generations of dependent events reproduced by a branching process. Although the occurrence of such space-time clusters is a general feature in different tectonic settings, seismic sequences seem to have marked differences from region to region: one example, among many others, is that seismic sequences of moderate magnitude in Italian Apennines seem to last longer than similar seismic sequences in California. In this work we investigate on the existence of possible differences in the earthquake clustering process in these two areas. At first, we separate the triggered and background components of seismicity in the Italian and Southern California seismic catalog. Then we study the space-time domain of the triggered earthquakes with the aim to identify possible variations in the triggering properties across the two regions. In the second part of the work we focus our attention on the characteristics of the background seismicity in both seismic catalogs. The assumption of time stationarity of the background seismicity (which includes both cluster parents and isolated events) is still under debate. Some authors suggest that the independent component of seismicity could undergo transient perturbations at various time scales due to different physical mechanisms, such as, for example, viscoelastic relaxation, presence of fluids, non-stationary plate motion, etc, whose impact may depend on the tectonic setting. Here we test if the background seismicity in the two regions can be satisfactorily described by the time

  5. SQL Triggers Reacting on Time Events: An Extension Proposal

    NASA Astrophysics Data System (ADS)

    Behrend, Andreas; Dorau, Christian; Manthey, Rainer

    Being able to activate triggers at timepoints reached or after time intervals elapsed has been acknowledged by many authors as a valuable functionality of a DBMS. Recently, the interest in time-based triggers has been renewed in the context of data stream monitoring. However, up till now SQL triggers react to data changes only, even though research proposals and prototypes have been supporting several other event types, in particular time-based ones, since long. We therefore propose a seamless extension of the SQL trigger concept by time-based triggers, focussing on semantic issues arising from such an extension.

  6. The Roles of Autophagy and the Inflammasome during Environmental Stress-Triggered Skin Inflammation

    PubMed Central

    Chen, Rong-Jane; Lee, Yu-Hsuan; Yeh, Ya-Ling; Wang, Ying-Jan; Wang, Bour-Jr

    2016-01-01

    Inflammatory skin diseases are the most common problem in dermatology. The induction of skin inflammation by environmental stressors such as ultraviolet radiation (UVR), hexavalent chromium (Cr(VI)) and TiO2/ZnO/Ag nanoparticles (NPs) has been demonstrated previously. Recent studies have indicated that the inflammasome is often wrongly activated by these environmental irritants, thus inducing massive inflammation and resulting in the development of inflammatory diseases. The regulation of the inflammasome with respect to skin inflammation is complex and is still not completely understood. Autophagy, an intracellular degradation system that is associated with the maintenance of cellular homeostasis, plays a key role in inflammasome inactivation. As a housekeeping pathway, cells utilize autophagy to maintain the homeostasis of the organ structure and function when exposed to environmental stressors. However, only a few studies have examined the effect of autophagy and/or the inflammasome on skin pathogenesis. Here we review recent findings regarding the involvement of autophagy and inflammasome activation during skin inflammation. We posit that autophagy induction is a novel mechanism inter-modulating environmental stressor-induced skin inflammation. We also attempt to highlight the role of the inflammasome and the possible underlying mechanisms and pathways reflecting the pathogenesis of skin inflammation induced by UVR, Cr(VI) and TiO2/ZnO/Ag NPs. A more profound understanding about the crosstalk between autophagy and the inflammasome will contribute to the development of prevention and intervention strategies against human skin disease. PMID:27941683

  7. Moisture-triggered physically transient electronics

    PubMed Central

    Gao, Yang; Zhang, Ying; Wang, Xu; Sim, Kyoseung; Liu, Jingshen; Chen, Ji; Feng, Xue; Xu, Hangxun; Yu, Cunjiang

    2017-01-01

    Physically transient electronics, a form of electronics that can physically disappear in a controllable manner, is very promising for emerging applications. Most of the transient processes reported so far only occur in aqueous solutions or biofluids, offering limited control over the triggering and degradation processes. We report novel moisture-triggered physically transient electronics, which exempt the needs of resorption solutions and can completely disappear within well-controlled time frames. The triggered transient process starts with the hydrolysis of the polyanhydride substrate in the presence of trace amounts of moisture in the air, a process that can generate products of corrosive organic acids to digest various inorganic electronic materials and components. Polyanhydride is the only example of polymer that undergoes surface erosion, a distinct feature that enables stable operation of the functional devices over a predefined time frame. Clear advantages of this novel triggered transience mode include that the lifetime of the devices can be precisely controlled by varying the moisture levels and changing the composition of the polymer substrate. The transience time scale can be tuned from days to weeks. Various transient devices, ranging from passive electronics (such as antenna, resistor, and capacitor) to active electronics (such as transistor, diodes, optoelectronics, and memories), and an integrated system as a platform demonstration have been developed to illustrate the concept and verify the feasibility of this design strategy. PMID:28879237

  8. LHCb detector and trigger performance in Run II

    NASA Astrophysics Data System (ADS)

    Francesca, Dordei

    2017-12-01

    The LHCb detector is a forward spectrometer at the LHC, designed to perform high precision studies of b- and c- hadrons. In Run II of the LHC, a new scheme for the software trigger at LHCb allows splitting the triggering of events into two stages, giving room to perform the alignment and calibration in real time. In the novel detector alignment and calibration strategy for Run II, data collected at the start of the fill are processed in a few minutes and used to update the alignment, while the calibration constants are evaluated for each run. This allows identical constants to be used in the online and offline reconstruction, thus improving the correlation between triggered and offline selected events. The required computing time constraints are met thanks to a new dedicated framework using the multi-core farm infrastructure for the trigger. The larger timing budget, available in the trigger, allows to perform the same track reconstruction online and offline. This enables LHCb to achieve the best reconstruction performance already in the trigger, and allows physics analyses to be performed directly on the data produced by the trigger reconstruction. The novel real-time processing strategy at LHCb is discussed from both the technical and operational point of view. The overall performance of the LHCb detector on the data of Run II is presented as well.

  9. Environmental setting and water-quality issues of the Mobile River Basin, Alabama, Georgia, Mississippi, and Tennessee

    USGS Publications Warehouse

    Johnson, Gregory C.; Kidd, Robert E.; Journey, Celeste A.; Zappia, Humbert; Atkins, J. Brian

    2002-01-01

    The Mobile River Basin is one of over 50 river basins and aquifer systems being investigated as part of the U.S. Geological Survey National Water-Quality Assessment (NAWQA) Program. This basin is the sixth largest river basin in the United States, and fourth largest in terms of streamflow, encompassing parts of Alabama, Georgia, Mississippi, and Tennessee. Almost two-thirds of the 44,000-square-mile basin is located in Alabama. Extensive water resources of the Mobile River Basin are influenced by an array of natural and cultural factors. These factors impart unique and variable qualities to the streams, rivers, and aquifers providing abundant habitat to sustain the diverse aquatic life in the basin. Data from Federal, State, and local agencies provide a description of the environmental setting of the Mobile River Basin. Environmental data include natural factors such as physiography, geology, soils, climate, hydrology, ecoregions, and aquatic ecology, and human factors such as reservoirs, land use and population change, water use, and water-quality issues. Characterization of the environmental setting is useful for understanding the physical, chemical, and biological characteristics of surface and ground water in the Mobile River Basin and the possible implications of that environmental setting for water quality. The Mobile River Basin encompasses parts of five physiographic provinces. Fifty-six percent of the basin lies within the East Gulf section of the Coastal Plain Physiographic Province. The remaining northeastern part of the basin lies, from west to east, within the Cumberland Plateau section of the Appalachian Plateaus Physiographic Province, the Valley and Ridge Physiographic Province, the Piedmont Physiographic Province, and the Blue Ridge Physiographic Province. Based on the 1991 land-use data, about 70 percent of the basin is forested, while agriculture, including livestock (poultry, cattle, and swine), row crops (cotton, corn, soybeans, sorghum, and

  10. Can Exposure to Environmental Chemicals Increase the Risk of Diabetes Type 1 Development?

    PubMed Central

    Stene, Lars Christian

    2015-01-01

    Type 1 diabetes mellitus (T1DM) is an autoimmune disease, where destruction of beta-cells causes insulin deficiency. The incidence of T1DM has increased in the last decades and cannot entirely be explained by genetic predisposition. Several environmental factors are suggested to promote T1DM, like early childhood enteroviral infections and nutritional factors, but the evidence is inconclusive. Prenatal and early life exposure to environmental pollutants like phthalates, bisphenol A, perfluorinated compounds, PCBs, dioxins, toxicants, and air pollutants can have negative effects on the developing immune system, resulting in asthma-like symptoms and increased susceptibility to childhood infections. In this review the associations between environmental chemical exposure and T1DM development is summarized. Although information on environmental chemicals as possible triggers for T1DM is sparse, we conclude that it is plausible that environmental chemicals can contribute to T1DM development via impaired pancreatic beta-cell and immune-cell functions and immunomodulation. Several environmental factors and chemicals could act together to trigger T1DM development in genetically susceptible individuals, possibly via hormonal or epigenetic alterations. Further observational T1DM cohort studies and animal exposure experiments are encouraged. PMID:25883945

  11. Can exposure to environmental chemicals increase the risk of diabetes type 1 development?

    PubMed

    Bodin, Johanna; Stene, Lars Christian; Nygaard, Unni Cecilie

    2015-01-01

    Type 1 diabetes mellitus (T1DM) is an autoimmune disease, where destruction of beta-cells causes insulin deficiency. The incidence of T1DM has increased in the last decades and cannot entirely be explained by genetic predisposition. Several environmental factors are suggested to promote T1DM, like early childhood enteroviral infections and nutritional factors, but the evidence is inconclusive. Prenatal and early life exposure to environmental pollutants like phthalates, bisphenol A, perfluorinated compounds, PCBs, dioxins, toxicants, and air pollutants can have negative effects on the developing immune system, resulting in asthma-like symptoms and increased susceptibility to childhood infections. In this review the associations between environmental chemical exposure and T1DM development is summarized. Although information on environmental chemicals as possible triggers for T1DM is sparse, we conclude that it is plausible that environmental chemicals can contribute to T1DM development via impaired pancreatic beta-cell and immune-cell functions and immunomodulation. Several environmental factors and chemicals could act together to trigger T1DM development in genetically susceptible individuals, possibly via hormonal or epigenetic alterations. Further observational T1DM cohort studies and animal exposure experiments are encouraged.

  12. Industrial accidents triggered by lightning.

    PubMed

    Renni, Elisabetta; Krausmann, Elisabeth; Cozzani, Valerio

    2010-12-15

    Natural disasters can cause major accidents in chemical facilities where they can lead to the release of hazardous materials which in turn can result in fires, explosions or toxic dispersion. Lightning strikes are the most frequent cause of major accidents triggered by natural events. In order to contribute towards the development of a quantitative approach for assessing lightning risk at industrial facilities, lightning-triggered accident case histories were retrieved from the major industrial accident databases and analysed to extract information on types of vulnerable equipment, failure dynamics and damage states, as well as on the final consequences of the event. The most vulnerable category of equipment is storage tanks. Lightning damage is incurred by immediate ignition, electrical and electronic systems failure or structural damage with subsequent release. Toxic releases and tank fires tend to be the most common scenarios associated with lightning strikes. Oil, diesel and gasoline are the substances most frequently released during lightning-triggered Natech accidents. Copyright © 2010 Elsevier B.V. All rights reserved.

  13. Internally versus externally mediated triggers in the acquisition of visual targets in the horizontal plane.

    PubMed

    Kolev, Ognyan I; Reschke, Millard F

    2014-06-01

    In an operational setting acquisition of visual targets using both head and eye movements can be driven by memorized sequence of commands - internal triggering (IT) or by commands issued through secondary operator - external triggering (ET). The primary objective of our research was to examine differences in target acquisition using IT compared with ET. Using a forced time optimal strategy eight subjects were required to acquire targets with angular offsets of ±20°, 30° and 60° along the horizontal plane in both IT and ET conditions. The data showed that the eye/head latency difference in IT condition is longer than that for ET, the target acquisition time is also longer for IT commands. Consistent with this finding were similar results when examining the peak head velocity and peak head acceleration. Under IT protocol head amplitude is higher than when using ET. In conclusion, the study demonstrates that the pattern of performance of target acquisition task is influenced by the way of command triggering. Copyright © 2014 Elsevier B.V. All rights reserved.

  14. Triggering of leukocytes by phase contrast in imaging cytometry with scanning fluorescence microscope (SFM)

    NASA Astrophysics Data System (ADS)

    Bocsi, József; Pierzchalski, Arkadiusz; Marecka, Monika; Malkusch, Wolf; Tárnok, Attila

    2009-02-01

    Slide-based cytometry (SBC) leads to breakthrough in cytometry of cells in tissues, culture and suspension. Carl Zeiss Imaging Solutions' new automated SFM combines imaging with cytometry. A critical step in image analysis is selection of appropriate triggering signal to detect all objects. Without correct target cell definition analysis is hampered. DNA-staining is among the most common triggering signals. However, the majority of DNA-dyes yield massive spillover into other fluorescence channels limiting their application. By microscopy objects of >5μm diameter can be easily detected by phase-contrast signal (PCS) without any staining. Aim was to establish PCS - triggering for cell identification. Axio Imager.Z1 motorized SFM was used (high-resolution digital camera, AxioCam MRm; AxioVision software: automatic multi-channel scanning, analysis). Leukocytes were stained with FITC (CD4, CD8) and APC (CD3) labelled antibodies in combinations using whole blood method. Samples were scanned in three channels (PCS/FITC/APC). Exposition-times for PCS were set as low as possible; the detection efficiency was verified by fluorescence. CD45-stained leukocytes were counted and compared to the number of PCS detected events. Leukocyte subtyping was compared with other cytometers. In focus the PCS of cells showed ring-form that was not optimal for cell definition. Out of focus PCS allows more effective qualitative and quantitative cell analyses. PCS was an accurate triggering signal for leukocytes enabling cell counting and discrimination of leukocytes from platelets. Leukocyte subpopulation frequencies were comparable to those obtained by other cytometers. In conclusion PCS is a suitable trigger-signal not interfering with fluorescence detection.

  15. Spark gaps synchronization using electrical trigger pulses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Agarwal, Ritu; Saroj, P.C.; Sharma, Archana

    In pulse power systems, it is required to have synchronized triggering of two or more high voltage spark gaps capable of switching large currents, using electrical trigger pulses. This paper intends to study the synchronization of spark gaps using electrical trigger. The trigger generator consists of dc supply, IGBT switch and driver circuit which generates 8kV, 400ns (FWHM) pulses. The experiment was carried out using two 0.15uF/50kV energy storage capacitors charged to 12kV and discharged through stainless steel spark gaps of diameter 9 mm across 10 ohm non inductive load. The initial experiment shows that synchronization has been achieved withmore » jitter of 50 to 100ns. Further studies carried out to reduce the jitter time by varying various electrical parameters will be presented. (author)« less

  16. Insight into multiple-triggering effect in DTSCRs for ESD protection

    NASA Astrophysics Data System (ADS)

    Zhang, Lizhong; Wang, Yuan; Wang, Yize; He, Yandong

    2017-07-01

    The diode-triggered silicon-controlled rectifier (DTSCR) is widely used for electrostatic discharge (ESD) protection in advanced CMOS process owing to its advantages, such as design simplification, adjustable trigger/holding voltage, low parasitic capacitance. However, the multiple-triggering effect in the typical DTSCR device may cause undesirable larger overall trigger voltage, which results in a reduced ESD safe margin. In previous research, the major cause is attributed to the higher current level required in the intrinsic SCR. The related discussions indicate that it seems to result from the current division rule between the intrinsic and parasitic SCR formed in the triggering process. In this letter, inserting a large space into the trigger diodes is proposed to get a deeper insight into this issue. The triggering current is observed to be regularly reduced along with the increased space, which confirms that the current division is determined by the parasitic resistance distributed between the intrinsic and parasitic SCR paths. The theoretical analysis is well confirmed by device simulation and transmission line pulse (TLP) test results. The reduced overall trigger voltage is achieved in the modified DTSCR structures due to the comprehensive result of the parasitic resistance vs triggering current, which indicates a minimized multiple-triggering effect. Project supported by the Beijing Natural Science Foundation, China (No. 4162030).

  17. Assessment of rainfall thresholds for landslide triggering in the Pacific Northwest: extreme short-term rainfall and long-term trends

    NASA Astrophysics Data System (ADS)

    Stanley, T.; Kirschbaum, D.; Sobieszczyk, S.; Jasinski, M. F.; Borak, J.; Yatheendradas, S.

    2017-12-01

    Landslides occur every year in the U.S. Pacific Northwest due to extreme rainfall, snow cover, and rugged topography. Data for 15,000 landslide events in Washington and Oregon were assembled from State Surveys, Departments of Transportation, a Global Landslide Catalog compiled by NASA, and other sources. This new inventory was evaluated against rainfall data from the National Climate Assessment (NCA) Land Data Assimilation System to characterize the regional rainfall conditions that trigger landslides. Analysis of these data sets indicates clear differences in triggering thresholds between extreme weather systems such as a Pineapple Express and the more typical peak seasonal rainfall between November and February. The study also leverages over 30 years of precipitation and land surface information to inform variability of landslide triggering over multiple decades and landslide trends within the region.

  18. A high power microwave triggered RF opening switch.

    PubMed

    Beeson, S; Dickens, J; Neuber, A

    2015-03-01

    A 4-port S-band waveguide structure was designed and fabricated such that a signal of any amplitude (less than 1 MW) can be switched from a normally closed state, <0.5 dB insertion loss (IL), to an open state >30 dB IL by initiating plasma in a gas cell situated at the junction of this waveguide and one propagating a megawatt level magnetron pulse. The 90/10 switching time is as low as 20 ns with a delay of ∼30 ns between the onset of the high power microwave pulse and the initial drop of the signal. Two ports of this device are for the high power triggering pulse while the other two ports are for the triggered signal in a Moreno-like coupler configuration. In order to maintain high isolation, these two sets of waveguides are rotated 90° from each other with a TE111 resonator/plasma cell located at the intersection. This manuscript describes the design and optimization of this structure using COMSOL 4.4 at the design frequency of 2.85 GHz, comparison of simulated scattering parameters with measured "cold tests" (testing without plasma), and finally the temporal waveforms of this device being used to successfully switch a low power CW signal from 2 W to <5 mW on a sub-microsecond timescale.

  19. Assessment of the environmental fate and effects of azilsartan, a selective antagonist of angiotensin II type 1.

    PubMed

    Weltman, R; Brands, C M J; Corral, E; Desmares-Koopmans, M J E; Migchielsen, M H J; Oudhoff, K A; de Roode, D F

    2012-06-01

    In this paper the results of a thorough evaluation of the environmental fate and effects of azilsartan are presented. Azilsartan medoxomil is administered as a pro-drug for the treatment of patients with essential hypertension. The pro-drug is converted by hydrolysis to the active pharmaceutical ingredient azilsartan. Laboratory tests to evaluate the environmental fate and effects of azilsartan medoxomil were conducted with azilsartan and performed in accordance with OECD test guidelines. The predicted environmental concentration (PEC) in surface water was estimated at 0.32 μg L(-1) (above the action limit of 0.01 μg L(-1)), triggering a Phase II assessment. Azilsartan is not readily biodegradable. Results of the water sediment study demonstrated significant shifting of azilsartan metabolites to sediment. Based on the equilibrium partitioning method, metabolites are unlikely to pose a risk to sediment-dwelling organisms. Ratios of the predicted environmental concentrations (PECs) to the predicted-no-effect concentrations (PNECs) did not exceed the relevant triggers, and the risk to aquatic, sewage treatment plant (STP), groundwater and sediment compartments was concluded acceptable. A terrestrial assessment was not triggered. Azilsartan poses an acceptable risk to the environment. Copyright © 2012 Elsevier Ltd. All rights reserved.

  20. Support vector machine incremental learning triggered by wrongly predicted samples

    NASA Astrophysics Data System (ADS)

    Tang, Ting-long; Guan, Qiu; Wu, Yi-rong

    2018-05-01

    According to the classic Karush-Kuhn-Tucker (KKT) theorem, at every step of incremental support vector machine (SVM) learning, the newly adding sample which violates the KKT conditions will be a new support vector (SV) and migrate the old samples between SV set and non-support vector (NSV) set, and at the same time the learning model should be updated based on the SVs. However, it is not exactly clear at this moment that which of the old samples would change between SVs and NSVs. Additionally, the learning model will be unnecessarily updated, which will not greatly increase its accuracy but decrease the training speed. Therefore, how to choose the new SVs from old sets during the incremental stages and when to process incremental steps will greatly influence the accuracy and efficiency of incremental SVM learning. In this work, a new algorithm is proposed to select candidate SVs and use the wrongly predicted sample to trigger the incremental processing simultaneously. Experimental results show that the proposed algorithm can achieve good performance with high efficiency, high speed and good accuracy.

  1. Earthquake triggering by transient and static deformations

    USGS Publications Warehouse

    Gomberg, J.; Beeler, N.M.; Blanpied, M.L.; Bodin, P.

    1998-01-01

    Observational evidence for both static and transient near-field and far-field triggered seismicity are explained in terms of a frictional instability model, based on a single degree of freedom spring-slider system and rate- and state-dependent frictional constitutive equations. In this study a triggered earthquake is one whose failure time has been advanced by ??t (clock advance) due to a stress perturbation. Triggering stress perturbations considered include square-wave transients and step functions, analogous to seismic waves and coseismic static stress changes, respectively. Perturbations are superimposed on a constant background stressing rate which represents the tectonic stressing rate. The normal stress is assumed to be constant. Approximate, closed-form solutions of the rate-and-state equations are derived for these triggering and background loads, building on the work of Dieterich [1992, 1994]. These solutions can be used to simulate the effects of static and transient stresses as a function of amplitude, onset time t0, and in the case of square waves, duration. The accuracies of the approximate closed-form solutions are also evaluated with respect to the full numerical solution and t0. The approximate solutions underpredict the full solutions, although the difference decreases as t0, approaches the end of the earthquake cycle. The relationship between ??t and t0 differs for transient and static loads: a static stress step imposed late in the cycle causes less clock advance than an equal step imposed earlier, whereas a later applied transient causes greater clock advance than an equal one imposed earlier. For equal ??t, transient amplitudes must be greater than static loads by factors of several tens to hundreds depending on t0. We show that the rate-and-state model requires that the total slip at failure is a constant, regardless of the loading history. Thus a static load applied early in the cycle, or a transient applied at any time, reduces the stress

  2. Multi-GHz Synchronous Waveform Acquisition With Real-Time Pattern-Matching Trigger Generation

    NASA Astrophysics Data System (ADS)

    Kleinfelder, Stuart A.; Chiang, Shiuh-hua Wood; Huang, Wei

    2013-10-01

    A transient waveform capture and digitization circuit with continuous synchronous 2-GHz sampling capability and real-time programmable windowed trigger generation has been fabricated and tested. Designed in 0.25 μm CMOS, the digitizer contains a circular array of 128 sample and hold circuits for continuous sample acquisition, and attains 2-GHz sample speeds with over 800-MHz analog bandwidth. Sample clock generation is synchronous, combining a phase-locked loop for high-speed clock generation and a high-speed fully-differential shift register for distributing clocks to all 128 sample circuits. Using two comparators per sample, the sampled voltage levels are compared against two reference levels, a high threshold and a low threshold, that are set via per-comparator digital to analog converters (DACs). The 256 per-comparator 5-bit DACs compensate for comparator offsets and allow for fine reference level adjustment. The comparator results are matched in 8-sample-wide windows against up to 72 programmable patterns in real time using an on-chip programmable logic array. Each 8-sample trigger window is equivalent to 4 ns of acquisition, overlapped sample by sample in a circular fashion through the entire 128-sample array. The 72 pattern-matching trigger criteria can be programmed to be any combination of High-above the high threshold, Low-below the low threshold, Middle-between the two thresholds, or “Don't Care”-any state is accepted. A trigger pattern of “HLHLHLHL,” for example, watches for a waveform that is oscillating at about 1 GHz given the 2-GHz sample rate. A trigger is flagged in under 20 ns if there is a match, after which sampling is stopped, and on-chip digitization can proceed via 128 parallel 10-bit converters, or off-chip conversion can proceed via an analog readout. The chip exceeds 11 bits of dynamic range, nets over 800-MHz -3-dB bandwidth in a realistic system, and jitter in the PLL-based sampling clock has been measured to be about 1 part

  3. Stress/strain changes and triggered seismicity at The Geysers, California

    USGS Publications Warehouse

    Gomberg, J.; Davis, S.

    1996-01-01

    The principal results of this study of remotely triggered seismicity in The Geysers geothermal field are the demonstration that triggering (initiation of earthquake failure) depends on a critical strain threshold and that the threshold level increases with decreasing frequency or equivalently, depends on strain rate. This threshold function derives from (1) analyses of dynamic strains associated with surface waves of the triggering earthquakes, (2) statistically measured aftershock zone dimensions, and (3) analytic functional representations of strains associated with power production and tides. The threshold is also consistent with triggering by static strain changes and implies that both static and dynamic strains may cause aftershocks. The observation that triggered seismicity probably occurs in addition to background activity also provides an important constraint on the triggering process. Assuming the physical processes underlying earthquake nucleation to be the same, Gomberg [this issue] discusses seismicity triggered by the MW 7.3 Landers earthquake, its constraints on the variability of triggering thresholds with site, and the implications of time delays between triggering and triggered earthquakes. Our results enable us to reject the hypothesis that dynamic strains simply nudge prestressed faults over a Coulomb failure threshold sooner than they would have otherwise. We interpret the rate-dependent triggering threshold as evidence of several competing processes with different time constants, the faster one(s) facilitating failure and the other(s) inhibiting it. Such competition is a common feature of theories of slip instability. All these results, not surprisingly, imply that to understand earthquake triggering one must consider not only simple failure criteria requiring exceedence of some constant threshold but also the requirements for generating instabilities.

  4. Stress/strain changes and triggered seismicity at The Geysers, California

    NASA Astrophysics Data System (ADS)

    Gomberg, Joan; Davis, Scott

    1996-01-01

    The principal results of this study of remotely triggered seismicity in The Geysers geothermal field are the demonstration that triggering (initiation of earthquake failure) depends on a critical strain threshold and that the threshold level increases with decreasing frequency, or, equivalently, depends on strain rate. This threshold function derives from (1) analyses of dynamic strains associated with surface waves of the triggering earthquakes, (2) statistically measured aftershock zone dimensions, and (3) analytic functional representations of strains associated with power production and tides. The threshold is also consistent with triggering by static strain changes and implies that both static and dynamic strains may cause aftershocks. The observation that triggered seismicity probably occurs in addition to background activity also provides an important constraint on the triggering process. Assuming the physical processes underlying earthquake nucleation to be the same, Gomberg [this issue] discusses seismicity triggered by the MW 7.3 Landers earthquake, its constraints on the variability of triggering thresholds with site, and the implications of time delays between triggering and triggered earthquakes. Our results enable us to reject the hypothesis that dynamic strains simply nudge prestressed faults over a Coulomb failure threshold sooner than they would have otherwise. We interpret the rate-dependent triggering threshold as evidence of several competing processes with different time constants, the faster one(s) facilitating failure and the other(s) inhibiting it. Such competition is a common feature of theories of slip instability. All these results, not surprisingly, imply that to understand earthquake triggering one must consider not only simple failure criteria requiring exceedence of some constant threshold but also the requirements for generating instabilities.

  5. Geostatistics and GIS: tools for characterizing environmental contamination.

    PubMed

    Henshaw, Shannon L; Curriero, Frank C; Shields, Timothy M; Glass, Gregory E; Strickland, Paul T; Breysse, Patrick N

    2004-08-01

    Geostatistics is a set of statistical techniques used in the analysis of georeferenced data that can be applied to environmental contamination and remediation studies. In this study, the 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) contamination at a Superfund site in western Maryland is evaluated. Concern about the site and its future clean up has triggered interest within the community because residential development surrounds the area. Spatial statistical methods, of which geostatistics is a subset, are becoming increasingly popular, in part due to the availability of geographic information system (GIS) software in a variety of application packages. In this article, the joint use of ArcGIS software and the R statistical computing environment are demonstrated as an approach for comprehensive geostatistical analyses. The spatial regression method, kriging, is used to provide predictions of DDE levels at unsampled locations both within the site and the surrounding areas where residential development is ongoing.

  6. Networked event-triggered control: an introduction and research trends

    NASA Astrophysics Data System (ADS)

    Mahmoud, Magdi S.; Sabih, Muhammad

    2014-11-01

    A physical system can be studied as either continuous time or discrete-time system depending upon the control objectives. Discrete-time control systems can be further classified into two categories based on the sampling: (1) time-triggered control systems and (2) event-triggered control systems. Time-triggered systems sample states and calculate controls at every sampling instant in a periodic fashion, even in cases when states and calculated control do not change much. This indicates unnecessary and useless data transmission and computation efforts of a time-triggered system, thus inefficiency. For networked systems, the transmission of measurement and control signals, thus, cause unnecessary network traffic. Event-triggered systems, on the other hand, have potential to reduce the communication burden in addition to reducing the computation of control signals. This paper provides an up-to-date survey on the event-triggered methods for control systems and highlights the potential research directions.

  7. A search in strainmeter data for slow slip associated with triggered and ambient tremor near Parkfield, California

    USGS Publications Warehouse

    Smith, E.F.; Gomberg, J.

    2009-01-01

    We test the hypothesis that, as in subduction zones, slow slip facilitates triggered and ambient tremor in the transform boundary setting of California. Our study builds on the study of Peng et al. (2009) of triggered and ambient tremor near Parkfield, California during time intervals surrounding 31, potentially triggering, M ≥ 7.5 teleseismic earthquakes; waves from 10 of these triggered tremor and 29 occurred in periods of ambient tremor activity. We look for transient slow slip during 3-month windows that include 11 of these triggering and nontriggering teleseisms, using continuous strain data recorded on two borehole Gladwin tensor strainmeters (GTSM) located within the distribution of tremor epicenters. We model the GTSM data assuming only tidal and “drift” signals are present and find no detectable slow slip, either ongoing when the teleseismic waves passed or triggered by them. We infer a conservative detection threshold of about 5 nanostrain for abrupt changes and about twice this for slowly evolving signals. This could be lowered slightly by adding analyses of other data types, modeled slow slip signals, and GTSM data calibration. Detection of slow slip also depends on the slipping fault's location and size, which we describe in terms of equivalent earthquake moment magnitude, M. In the best case of the GTSM above a very shallow slipping fault, detectable slip events must exceed M~2, and if the slow slip is beneath the seismogenic zone (below ~15 km depth), even M~5 events are likely to remain hidden.

  8. Investigation of Self Triggered Cosmic Ray Detectors using Silicon Photomultiplier

    NASA Astrophysics Data System (ADS)

    Knox, Adrian; Niduaza, Rommel; Hernandez, Victor; Ruiz, Daniel; Ramos, Daniel; Fan, Sewan; Fatuzzo, Laura; Ritt, Stefan

    2015-04-01

    The silicon photomultiplier (SiPM) is a highly sensitive light detector capable of measuring single photons. It costs a fraction of the photomultiplier tube and operates slightly above the breakdown voltage. At this conference we describe our investigation of SiPM, the multipixel photon counters (MPPC) from Hamamatsu as readout detectors for plastic scintillators working for detecting cosmic ray particles. Our setup consists of scintillator sheets embedded with blue to green wavelength shifting fibers optically coupled to MPPCs to detect scintillating light. Four detector assemblies would be constructed and arranged to work in self triggered mode. Using custom matching tee boxes, the amplified MPPC signals are fed to discriminators with threshold set to give a reasonable coincidence count rate. Moreover, the detector waveforms are digitized using a 5 Giga Samples per second waveform digitizer, the DRS4, and triggered with the coincidence logic to capture the MPPC waveforms. Offline analysis of the digitized waveforms is accomplished using the CERN package PAW and results of our experiments and the data analysis would also be discussed. US Department of Education Title V Grant Number PO31S090007.

  9. Cosmetics-triggered percutaneous remote control of transgene expression in mice

    PubMed Central

    Wang, Hui; Ye, Haifeng; Xie, Mingqi; Daoud El-Baba, Marie; Fussenegger, Martin

    2015-01-01

    Synthetic biology has significantly advanced the rational design of trigger-inducible gene switches that program cellular behavior in a reliable and predictable manner. Capitalizing on genetic componentry, including the repressor PmeR and its cognate operator OPmeR, that has evolved in Pseudomonas syringae pathovar tomato DC3000 to sense and resist plant-defence metabolites of the paraben class, we have designed a set of inducible and repressible mammalian transcription-control devices that could dose-dependently fine-tune transgene expression in mammalian cells and mice in response to paraben derivatives. With an over 60-years track record as licensed preservatives in the cosmetics industry, paraben derivatives have become a commonplace ingredient of most skin-care products including shower gels, cleansing toners and hand creams. As parabens can rapidly reach the bloodstream of mice following topical application, we used this feature to percutaneously program transgene expression of subcutaneous designer cell implants using off-the-shelf commercial paraben-containing skin-care cosmetics. The combination of non-invasive, transdermal and orthogonal trigger-inducible remote control of transgene expression may provide novel opportunities for dynamic interventions in future gene and cell-based therapies. PMID:25943548

  10. EMIC triggered chorus emissions in Cluster data

    NASA Astrophysics Data System (ADS)

    Grison, B.; SantolíK, O.; Cornilleau-Wehrlin, N.; Masson, A.; Engebretson, M. J.; Pickett, J. S.; Omura, Y.; Robert, P.; Nomura, R.

    2013-03-01

    Electromagnetic ion cyclotron (EMIC) triggered chorus emissions have recently been a subject of several experimental, theoretical and simulation case studies, noting their similarities with whistler-mode chorus. We perform a survey of 8 years of Cluster data in order to increase the database of EMIC triggered emissions. The results of this is that EMIC triggered emissions have been unambiguously observed for only three different days. These three events are studied in detail. All cases have been observed at the plasmapause between 22 and 24 magnetic local time (MLT) and between - 15° and 15° magnetic latitude (λm). Triggered emissions are also observed for the first time below the local He+ gyrofrequency (fHe+). The number of events is too low to produce statistical results, nevertheless we point out a variety of common properties of those waves. The rising tones have a high level of coherence and the waves propagate away from the equatorial region. The propagation angle and degree of polarization are related to the distance from the equator, whereas the slope and the frequency extent vary from one event to the other. From the various spacecraft separations, we determine that the triggering process is a localized phenomenon in space and time. However, we are unable to determine the occurrence rates of these waves. Small frequency extent rising tones are more common than large ones. The newly reported EMIC triggered events are generally observed during periods of large AE index values and in time periods close to solar maximum.

  11. Ultrasonically triggered ignition at liquid surfaces.

    PubMed

    Simon, Lars Hendrik; Meyer, Lennart; Wilkens, Volker; Beyer, Michael

    2015-01-01

    Ultrasound is considered to be an ignition source according to international standards, setting a threshold value of 1mW/mm(2) [1] which is based on theoretical estimations but which lacks experimental verification. Therefore, it is assumed that this threshold includes a large safety margin. At the same time, ultrasound is used in a variety of industrial applications where it can come into contact with explosive atmospheres. However, until now, no explosion accidents have been reported in connection with ultrasound, so it has been unclear if the current threshold value is reasonable. Within this paper, it is shown that focused ultrasound coupled into a liquid can in fact ignite explosive atmospheres if a specific target positioned at a liquid's surface converts the acoustic energy into a hot spot. Based on ignition tests, conditions could be derived that are necessary for an ultrasonically triggered explosion. These conditions show that the current threshold value can be significantly augmented. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Earthquake Tidal Triggering Associated with the 2015 Eruption of Axial Seamount

    NASA Astrophysics Data System (ADS)

    Wilcock, W. S. D.; Tolstoy, M.; Waldhauser, F.; Tan, Y. J.; Garcia, C.; Arnulf, A. F.; Crone, T. J.

    2016-12-01

    The Ocean Observatories Initiative's real time cabled observatory at Axial Seamount includes a seven station seismic network that spans the southern half of the summit caldera. The network has been in operation since late 2014 and, in conjunction with geodetic sensors on the observatory, has recorded an exceptional data set to characterize the dynamics of the caldera through the April 2015 eruption. Prior to the eruption, earthquake rates were high and double-difference locations show that the inflation of the volcano was accommodated by deformation on an outward dipping caldera ring fault. The onset of the eruption was marked by a seismic crisis on April 24 and rapid deflation of the volcano; the caldera ring fault accommodated deflation and guided a dike beneath the east rim of the caldera. The seismic crisis was followed by a steady decline in the rates of earthquakes and deflation. Numerous seafloor explosions document the timing and location of lava flows in the caldera and on the north rift of the seamount. They ceased after about a month when the volcano started to reinflate. Efforts are presently underway to improve the resolution of hypocenters both through the use of cross-correlation-based double-difference hypocenter locations (Tan et al., this meeting) and by the incorporation of three-dimensional velocity models that account for the heterogeneous structure of the volcano. One particularly interesting aspect of the seismicity is the tidal triggering. Prior to the eruption, when the volcano is critically stressed, the earthquakes show a strong tidal triggering signal with higher rates of seismicity near low tides when faults are unclamped. Earthquake rates at the lowest tides are about six times those at the highest tides. There are also noticeable temporo-spatial patterns in the earthquake swarms that occur at each low tide suggesting that the characteristics of tidal triggering may be spatial dependent. Following the eruption, only a weak tidal

  13. The toll of toxics: investigating environmental contaminants

    USGS Publications Warehouse

    Sparling, Donald W.; Rattner, Barnett A.; Barclay, John S.

    2010-01-01

    On Earth Day of this year, the British Petroleum-operated Deepwater Horizon oil drilling rig exploded in the Gulf of Mexico, 41 miles off the Louisiana coast. The blast killed 11 workers, injured 17, launched a massive oil spill, and triggered an environmental catastrophe—the full impact of which may not be realized for years.

  14. Health-related disparities: influence of environmental factors.

    PubMed

    Olden, Kenneth; White, Sandra L

    2005-07-01

    populations, but their frequency can vary substantially,rendering individuals or groups more or less susceptible to particular environmental exposures. Such findings are consistent with the highly publicized analogy, "genetics loads the gun, but the environment pulls the trigger." That is, one can inherit the genetic predisposition to develop a disease but will do so only if or when exposed to the environmental trigger. Poor people have approximately the same genetic makeup as everyone else,but they have the unfortunate experience of living and working in environments containing multiple and high levels of carcinogens or other toxicants capable of interacting with susceptibility genes to cause disease.Furthermore, certain disadvantaged ethnic groups may have a higher incidence of certain susceptible genes that render them more vulnerable to adverse effects of the environments they inhabit. For both of these reasons,much of the nation's disease burden could likely be reduced through better environmental protection practices, especially in low-income and minority communities. Of the many implications of polymorphisms and frequency variations for public health and the practice of medicine, however, none is more urgent than the choice of drugs in therapy. Using such knowledge,randomized trials have identified race-specific drug response differences between blacks and whites [42].To date, most knowledge of the health effects of environmental factors is derived from studies of single agents. The reality, though, is that environmental contributions to health disparities are mostly from multiple agents. These simultaneous exposures to multiple risk factors, which may accumulate or interact synergistically, remain to be fully explained and defined.Finally, health disparity is a significant public health problem that cannot be solved using "business as usual" approaches for funding and priority setting. The current emphasis on basic and clinical research at the exclusion of public

  15. Use of GPUs in Trigger Systems

    NASA Astrophysics Data System (ADS)

    Lamanna, Gianluca

    In recent years the interest for using graphics processor (GPU) in general purpose high performance computing is constantly rising. In this paper we discuss the possible use of GPUs to construct a fast and effective real time trigger system, both in software and hardware levels. In particular, we study the integration of such a system in the NA62 trigger. The first application of GPUs for rings pattern recognition in the RICH will be presented. The results obtained show that there are not showstoppers in trigger systems with relatively low latency. Thanks to the use of off-the-shelf technology, in continous development for purposes related to video game and image processing market, the architecture described would be easily exported to other experiments, to build a versatile and fully customizable online selection.

  16. A multi-purpose open-source triggering platform for magnetic resonance

    NASA Astrophysics Data System (ADS)

    Ruytenberg, T.; Webb, A. G.; Beenakker, J. W. M.

    2014-10-01

    Many MR scans need to be synchronised with external events such as the cardiac or respiratory cycles. For common physiological functions commercial trigger equipment exists, but for more experimental inputs these are not available. This paper describes the design of a multi-purpose open-source trigger platform for MR systems. The heart of the system is an open-source Arduino Due microcontroller. This microcontroller samples an analogue input and digitally processes these data to determine the trigger. The output of the microcontroller is programmed to mimic a physiological signal which is fed into the electrocardiogram (ECG) or pulse oximeter port of MR scanner. The microcontroller is connected to a Bluetooth dongle that allows wireless monitoring and control outside the scanner room. This device can be programmed to generate a trigger based on various types of input. As one example, this paper describes how it can be used as an acoustic cardiac triggering unit. For this, a plastic stethoscope is connected to a microphone which is used as an input for the system. This test setup was used to acquire retrospectively-triggered cardiac scans in ten volunteers. Analysis showed that this platform produces a reliable trigger (>99% triggers are correct) with a small average 8 ms variation between the exact trigger points.

  17. Dynamic Earthquake Triggering on Seismogenic Faults in Oklahoma

    NASA Astrophysics Data System (ADS)

    Qin, Y.; Chen, X.; Peng, Z.; Aiken, C.

    2016-12-01

    Regions with high pore pressure are generally more susceptible to dynamic triggering from transient stress change caused by surface wave of distant earthquakes. The stress threshold from triggering studies can help understand the stress state of seismogenic faults. The recent dramatic seismicity increase in central US provides a rich database for assessing dynamic triggering phenomena. We begin our study by conducting a systematic analysis of dynamic triggering for the continental U.S using ANSS catalog (with magnitude of completeness Mc=3) from 49 global mainshocks (Ms>6.5, depth<100km, estimated dynamic stress>1kPa). We calculate β value for each 1° by 1° bins in 30 days before and 10 days after the mainshock. To identify regions that experience triggering from a distant mainshock, we generate a stacked map using β≥2 - which represents significant seismicity rate increase. As expected, the geothermal and volcanic fields in California show clear response to distant earthquakes. We also note areas in Oklahoma and north Texas show enhanced triggering, where wastewater-injection induced seismicity are occurring. Next we focus on Oklahoma and use a local catalog from Oklahoma Geological Survey with lower completeness threshold Mc to calculate the beta map in 0.2° by 0.2° bins for each selected mainshock to obtain finer spatial resolutions of the triggering behavior. For those grids with β larger than 2.0, we use waveforms from nearby stations to search for triggered events. The April 2015 M7.8 Nepal earthquake causes a statistically significant increase of local seismicity (β=3.5) in the Woodward area (west Oklahoma) during an on-going earthquake sequence. By visually examining the surface wave from the nearest station, we identify 3 larger local events, and 10 additional smaller events with weaker but discernable amplitude. Preliminary analysis shows that the triggering is related to Rayleigh wave, which would cause dilatational or shear stress changes

  18. The upgrade of the ATLAS first-level calorimeter trigger

    NASA Astrophysics Data System (ADS)

    Yamamoto, Shimpei; Atlas Collaboration

    2016-07-01

    The first-level calorimeter trigger (L1Calo) had operated successfully through the first data taking phase of the ATLAS experiment at the CERN Large Hadron Collider. Towards forthcoming LHC runs, a series of upgrades is planned for L1Calo to face new challenges posed by the upcoming increases of the beam energy and the luminosity. This paper reviews the ATLAS L1Calo trigger upgrade project that introduces new architectures for the liquid-argon calorimeter trigger readout and the L1Calo trigger processing system.

  19. World soccer cup as a trigger of cardiovascular events.

    PubMed

    Borges, Daniel Guilherme Suzuki; Monteiro, Rosane Aparecida; Schmidt, André; Pazin-Filho, Antonio

    2013-06-01

    Acute coronary syndromes are the major cause of death in Brazil and in the world. External stimuli, known also as triggers, such as emotional state and activity, may generate physiopathological changes that can trigger acute coronary syndromes. Among the studied triggers, the impact of stressful events, such as soccer championships, are controversial in literature and there is no effective data on the Brazilian population. To evaluate the acute effects of environmental stress induced by soccer games of the World Soccer Cup on increased incidence of cardiovascular diseases in Brazil. Public data were obtained from the Unified Health System (Sistema Único de Saúde), regarding hospital admissions that had the International Code Disease of acute coronary syndromes from May to August, in 1998, 2002, 2006 and 2010 (155,992 admissions). Analysis was restricted to patients older than 35 years and admitted by clinical specialties. The incidence of myocardial infarction, angina and mortality were compared among days without World Cup soccer games (Group I: 144,166; 61.7 ± 12.3; 59.4% males); on days when there were no Brazil's soccer team matches (Group II: 9,768; 61.8 ± 12.3; 60.0% males); and days when there were Brazil's soccer team matches (Group III; 2,058; 61.6 ± 12.6; 57.8% males). Logistic regression was used to adjust to age, gender, population density and number of medical assistance units. The incidence of myocardial infarction increased during the period of World Cup soccer games (1.09; 95%CI = 1.05-1.15) and days when there were Brazil's matches (1.16; 95%CI = 1.06-1.27). There was no impact on mortality during the Cup (1.00; CI 95% = 0.93-1.08) and Brazil's matches (1.04; 95%CI = 0.93-1.22). World Cup soccer games and, specially, Brazil's matches have an impact on the incidence of myocardial infarction, but not on in-hospital mortality.

  20. Muon Trigger for Mobile Phones

    NASA Astrophysics Data System (ADS)

    Borisyak, M.; Usvyatsov, M.; Mulhearn, M.; Shimmin, C.; Ustyuzhanin, A.

    2017-10-01

    The CRAYFIS experiment proposes to use privately owned mobile phones as a ground detector array for Ultra High Energy Cosmic Rays. Upon interacting with Earth’s atmosphere, these events produce extensive particle showers which can be detected by cameras on mobile phones. A typical shower contains minimally-ionizing particles such as muons. As these particles interact with CMOS image sensors, they may leave tracks of faintly-activated pixels that are sometimes hard to distinguish from random detector noise. Triggers that rely on the presence of very bright pixels within an image frame are not efficient in this case. We present a trigger algorithm based on Convolutional Neural Networks which selects images containing such tracks and are evaluated in a lazy manner: the response of each successive layer is computed only if activation of the current layer satisfies a continuation criterion. Usage of neural networks increases the sensitivity considerably comparable with image thresholding, while the lazy evaluation allows for execution of the trigger under the limited computational power of mobile phones.

  1. Gender differences in autoimmunity associated with exposure to environmental factors

    PubMed Central

    Pollard, K. Michael

    2011-01-01

    Autoimmunity is thought to result from a combination of genetics, environmental triggers, and stochastic events. Gender is also a significant risk factor with many diseases exhibiting a female bias. Although the role of environmental triggers, especially medications, in eliciting autoimmunity is well established less is known about the interplay between gender, the environment and autoimmunity. This review examines the contribution of gender in autoimmunity induced by selected chemical, physical and biological agents in humans and animal models. Epidemiological studies reveal that environmental factors can be associated with a gender bias in human autoimmunity. However many studies show that the increased risk of autoimmunity is often influenced by occupational exposure or other gender biased activities. Animal studies, although often prejudiced by the exclusive use of female animals, reveal that gender bias can be strain specific suggesting an interaction between sex chromosome complement and background genes. This observation has important implications because it argues that within a gender biased disease there may be individuals in which gender does not contribute to autoimmunity. Exposure to environmental factors, which encompasses everything around us, adds an additional layer of complexity. Understanding how the environment influences the relationship between sex chromosome complement and innate and adaptive immune responses will be essential in determining the role of gender in environmentally-induced autoimmunity. PMID:22137891

  2. Stereotype threat as a trigger of mind-wandering in older adults.

    PubMed

    Jordano, Megan L; Touron, Dayna R

    2017-05-01

    Older adults (OAs) report less overall mind-wandering than younger adults (YAs) but more task-related interference (TRI; mind-wandering about the task). The current study examined TRI while manipulating older adults' performance-related concerns. We compared groups for which memory-related stereotype threat (ST) was activated or relieved to a control group. Participants completed an operation span task containing mind-wandering probes. ST-activated OAs reported more TRI than ST-relieved OAs and had worse performance on the operation span task. This study illustrates that environmental context triggers current concerns and determines, in part, the frequency and content of mind-wandering. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  3. The twilight zone: ambient light levels trigger activity in primitive ants

    PubMed Central

    Narendra, Ajay; Reid, Samuel F.; Hemmi, Jan M.

    2010-01-01

    Many animals become active during twilight, a narrow time window where the properties of the visual environment are dramatically different from both day and night. Despite the fact that many animals including mammals, reptiles, birds and insects become active in this specific temporal niche, we do not know what cues trigger this activity. To identify the onset of specific temporal niches, animals could anticipate the timing of regular events or directly measure environmental variables. We show that the Australian bull ant, Myrmecia pyriformis, starts foraging only during evening twilight throughout the year. The onset occurs neither at a specific temperature nor at a specific time relative to sunset, but at a specific ambient light intensity. Foraging onset occurs later when light intensities at sunset are brighter than normal or earlier when light intensities at sunset are darker than normal. By modifying ambient light intensity experimentally, we provide clear evidence that ants indeed measure light levels and do not rely on an internal rhythm to begin foraging. We suggest that the reason for restricting the foraging onset to twilight and measuring light intensity to trigger activity is to optimize the trade-off between predation risk and ease of navigation. PMID:20129978

  4. Does Cannabis Onset Trigger Cocaine Onset? A Case-Crossover Approach

    PubMed Central

    O’Brien, Megan S.; Comment, Leah Andrews; Liang, Kung Yee; Anthony, James C.

    2016-01-01

    Psychiatric researchers tend to select the discordant co-twin design when they seek to hold constant genetic influence while estimating exposure-associated disease risk. The epidemiologic case-crossover research design developed for the past two decades represents a viable alternative, not often seen in psychiatric studies. Here, we turn to the epidemiologic case-crossover approach to examine the idea that cannabis onset is a proximal trigger for cocaine use, with the power of ‘subject-as-own-control’ research used to hold constant antecedent characteristics of the individual drug user, including genetic influence and other traits experienced up to the time of the observed hazard and control intervals. Data are from newly incident cocaine users identified in the 2002–2006 U.S. National Surveys on Drug Use and Health. Among these cocaine users, 48 had both cannabis onset and cocaine onset in the same month-long hazard interval; the expected value is 30 users, based on the control interval we had pre-specified for case-crossover estimation (estimated relative risk, RR = 1.6; exact mid-p = 0.042). Within the framework of a subject-as-own-control design, the evidence is consistent with the hypothesis that cannabis onset is a proximal trigger for cocaine use, with genetic influences (and many environmental conditions and processes) held constant. Limitations are noted and implications discussed. PMID:22228642

  5. The ATLAS Level-1 Topological Trigger performance in Run 2

    NASA Astrophysics Data System (ADS)

    Riu, Imma; ATLAS Collaboration

    2017-10-01

    The Level-1 trigger is the first event rate reducing step in the ATLAS detector trigger system, with an output rate of up to 100 kHz and decision latency smaller than 2.5 μs. During the LHC shutdown after Run 1, the Level-1 trigger system was upgraded at hardware, firmware and software levels. In particular, a new electronics sub-system was introduced in the real-time data processing path: the Level-1 Topological trigger system. It consists of a single electronics shelf equipped with two Level-1 Topological processor blades. They receive real-time information from the Level-1 calorimeter and muon triggers, which is processed to measure angles between trigger objects, invariant masses or other kinematic variables. Complementary to other requirements, these measurements are taken into account in the final Level-1 trigger decision. The system was installed and commissioning started in 2015 and continued during 2016. As part of the commissioning, the decisions from individual algorithms were simulated and compared with the hardware response. An overview of the Level-1 Topological trigger system design, commissioning process and impact on several event selections are illustrated.

  6. A multi-purpose open-source triggering platform for magnetic resonance.

    PubMed

    Ruytenberg, T; Webb, A G; Beenakker, J W M

    2014-10-01

    Many MR scans need to be synchronised with external events such as the cardiac or respiratory cycles. For common physiological functions commercial trigger equipment exists, but for more experimental inputs these are not available. This paper describes the design of a multi-purpose open-source trigger platform for MR systems. The heart of the system is an open-source Arduino Due microcontroller. This microcontroller samples an analogue input and digitally processes these data to determine the trigger. The output of the microcontroller is programmed to mimic a physiological signal which is fed into the electrocardiogram (ECG) or pulse oximeter port of MR scanner. The microcontroller is connected to a Bluetooth dongle that allows wireless monitoring and control outside the scanner room. This device can be programmed to generate a trigger based on various types of input. As one example, this paper describes how it can be used as an acoustic cardiac triggering unit. For this, a plastic stethoscope is connected to a microphone which is used as an input for the system. This test setup was used to acquire retrospectively-triggered cardiac scans in ten volunteers. Analysis showed that this platform produces a reliable trigger (>99% triggers are correct) with a small average 8 ms variation between the exact trigger points. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Prevalence and triggers of anaphylactic events in schools.

    PubMed

    White, Martha V; Silvia, Suyapa; Muniz, Rafael; Herrem, Christopher; Hogue, Susan L

    2017-07-01

    Prevention and management of anaphylaxis in schools is an area of active interest as allergy and asthma rates in children continue to increase. A greater understanding of the prevalence and characteristics of anaphylaxis can help guide preventive and management strategies both within and outside of the school setting, with the goal of reducing morbidity and mortality. This study was performed to elucidate the epidemiology of and management strategies for anaphylaxis in the school setting. A cross-sectional, Web-based survey was administered to schools that participated in an initiative that provides stock epinephrine autoinjectors (EAIs) to qualifying U.S. schools. Representatives from participating schools completed a questionnaire regarding anaphylactic reactions that occurred during the 2014-2015 school year. Weighted analyses were performed to account for differential responses between schools that completed the survey and those that did not. A total of 12,275 of the 45,819 invited schools responded to the survey. The occurrence of one or more anaphylactic events was reported by 1358 schools. Most events (89.8% [1803/2008]) occurred in students. High school students accounted for the largest proportion of anaphylactic reactions among students (40.1% [723/1802]). Food was the most commonly identified anaphylaxis trigger across grade levels, seasons, and geographic regions. The trigger was unknown to the individual who experienced anaphylaxis in 21.8% of the events (436/1998). No known history of allergy or asthma was present in 24.5% (491/2001) and 51.3% (1026/2000) of affected individuals, respectively. Transportation to the hospital or clinic for further treatment and/or management was reported for 72.6% of the individuals with anaphylactic events (1450/1997). Results from the weighted analyses were similar to those of the unweighted analyses. Anaphylaxis occurred across grade levels and in individuals with or without known risk factors, which reinforced the

  8. Sensor-triggered sampling to determine instantaneous airborne vapor exposure concentrations.

    PubMed

    Smith, Philip A; Simmons, Michael K; Toone, Phillip

    2018-06-01

    It is difficult to measure transient airborne exposure peaks by means of integrated sampling for organic chemical vapors, even with very short-duration sampling. Selection of an appropriate time to measure an exposure peak through integrated sampling is problematic, and short-duration time-weighted average (TWA) values obtained with integrated sampling are not likely to accurately determine actual peak concentrations attained when concentrations fluctuate rapidly. Laboratory analysis for integrated exposure samples is preferred from a certainty standpoint over results derived in the field from a sensor, as a sensor user typically must overcome specificity issues and a number of potential interfering factors to obtain similarly reliable data. However, sensors are currently needed to measure intra-exposure period concentration variations (i.e., exposure peaks). In this article, the digitized signal from a photoionization detector (PID) sensor triggered collection of whole-air samples when toluene or trichloroethylene vapors attained pre-determined levels in a laboratory atmosphere generation system. Analysis by gas chromatography-mass spectrometry of whole-air samples (with both 37 and 80% relative humidity) collected using the triggering mechanism with rapidly increasing vapor concentrations showed good agreement with the triggering set point values. Whole-air samples (80% relative humidity) in canisters demonstrated acceptable 17-day storage recoveries, and acceptable precision and bias were obtained. The ability to determine exceedance of a ceiling or peak exposure standard by laboratory analysis of an instantaneously collected sample, and to simultaneously provide a calibration point to verify the correct operation of a sensor was demonstrated. This latter detail may increase the confidence in reliability of sensor data obtained across an entire exposure period.

  9. Divergence of developmental trajectories is triggered interactively by early social and ecological experience in a cooperative breeder

    PubMed Central

    Bohn, Lena; Oberhummer, Evelyne

    2017-01-01

    Cooperative breeders feature the highest level of social complexity among vertebrates. Environmental constraints foster the evolution of this form of social organization, selecting for both well-developed social and ecological competences. Cooperative breeders pursue one of two alternative social trajectories: delaying reproduction to care for the offspring of dominant breeders or dispersing early to breed independently. It is yet unclear which ecological and social triggers determine the choice between these alternatives and whether diverging developmental trajectories exist in cooperative vertebrates predisposing them to dispersal or philopatry. Here we experimentally reared juveniles of cooperatively breeding cichlid fish by varying the social environment and simulated predation threat in a two-by-two factorial long-term experiment. First, we show that individuals develop specialized behavioral competences, originating already in the early postnatal phase. Second, these specializations predisposed individuals to pursue different developmental trajectories and either to disperse early or to extend philopatry in adulthood. Thus, our results contrast with the proposition that social specializations in early ontogeny should be restricted to eusocial species. Importantly, social and ecological triggers were both required for the generation of divergent life histories. Our results thus confirm recent predictions from theoretical models that organisms should combine relevant information from different environmental cues to develop integrated phenotypes. PMID:29078289

  10. The trigger system of the JEM-EUSO Project

    NASA Astrophysics Data System (ADS)

    Bertaina, M.; Ebisuzaki, T.; Hamada, T.; Ikeda, H.; Kawasai, Y.; Sawabe, T.; Takahashi, Y.; JEM-EUSO Collaboration

    The trigger system of JEM-EUSO should face different major challenging points: a) cope with the limited down-link transmission rate from the ISS to Earth, by operating a severe on-board and on-time data reduction; b) use very fast, low power consuming and radiation hard electronics; c) have a high signal-over-noise performance and flexibility in order to lower as much as possible the energy threshold of the detector, adjust the system to a variable nightglow background, and trigger on different categories of events (images insisting on the same pixels or crossing huge portions of the entire focal surface). Based on the above stringent requirements, the main ingredients for the trigger logic are: the Gate Time Unit (GTU); the minimum number Nthresh of photo-electrons piling up in a GTU in a pixel to be fired; the persistency level Npers, in which fired pixels are over threshold; the localization and correlation in space and time of the fired pixels, that distinguish a real EAS from an accidental background enhancement. The core of the trigger logic is the Track Trigger Algorithm that has been specifically developed for this purpose. Its characteristics, preliminary performance and its possible implementation on FPGA or DSP will be discussed together with a general overview of the architecture of the triggering system of JEM-EUSO.

  11. Reviewing putative industrial triggering in pemphigus: cluster of pemphigus in the area near the wastewater treatment plant

    PubMed Central

    Gornowicz-Porowska, Justyna; Bartkiewicz, Paweł; Bowszyc-Dmochowska, Monika; Dmochowski, Marian

    2017-01-01

    A range of pemphigus is relatively rare potentially fatal group of autoimmune blistering dermatoses. Usually, there is no apparent triggering, while in some predisposed patients there are alleged environmental/industrial inducing factors. In a short time period (4 years), we diagnosed 3 novel cases of pemphigus (1 pemphigus vulgaris, 1 pemphigus foliaceus and 1 shift from pemphigus foliaceus into pemphigus vulgaris) at a clinical and laboratory level (ELISA, immunofluorescence studies). We discuss a possible common inducing mechanism as these patients inhabit one estate of the Poznan suburbia (Kozieglowy, population < 12,000), Greater Poland district, Poland, and review literature data on alleged pemphigus triggers. To the best of our knowledge, this is the first report exploring the putative association between pemphigus diseases and wastewater treatment plant waterborne or volatile by-products in the vicinity of such a facility. PMID:28670245

  12. Clinical relevance of contextual factors as triggers of placebo and nocebo effects in musculoskeletal pain.

    PubMed

    Rossettini, Giacomo; Carlino, Elisa; Testa, Marco

    2018-01-22

    Placebo and nocebo effects are embodied psycho-neurobiological responses capable of modulating pain and producing changes at different neurobiological, body at perceptual and cognitive levels. These modifications are triggered by different contextual factors (CFs) presented in the therapeutic encounter between patient and healthcare providers, such as healing rituals and signs. The CFs directly impact on the quality of the therapeutic outcome: a positive context, that is a context characterized by the presence of positive CFs, can reduce pain by producing placebo effects, while a negative context, characterized by the presence of negative CFs, can aggravate pain by creating nocebo effects. Despite the increasing interest about this topic; the detailed study of CFs as triggers of placebo and nocebo effects is still lacked in the management of musculoskeletal pain.Increasing evidence suggest a relevant role of CFs in musculoskeletal pain management. CFs are a complex sets of internal, external or relational elements encompassing: patient's expectation, history, baseline characteristics; clinician's behavior, belief, verbal suggestions and therapeutic touch; positive therapeutic encounter, patient-centered approach and social learning; overt therapy, posology of intervention, modality of treatment administration; marketing features of treatment and health care setting. Different explanatory models such as classical conditioning and expectancy can explain how CFs trigger placebo and nocebo effects. CFs act through specific neural networks and neurotransmitters that were described as mediators of placebo and nocebo effects.Available findings suggest a relevant clinical role and impact of CFs. They should be integrated in the clinical reasoning to increase the number of treatment solutions, boosts their efficacy and improve the quality of the decision-making. From a clinical perspective, the mindful manipulation of CFs represents a useful opportunity to enrich a well

  13. Reflecting on Functioning in Trigger Happy America

    ERIC Educational Resources Information Center

    Wolfsdorf, Adam

    2017-01-01

    Trigger warnings are posing serious threats to the ways that English educators can teach at the university level. If Aristotle--and Hillis-Miller years later--argue that literature must arouse and bring about catharsis, then proponents of trigger warnings are anaesthetising the power of words and watering down their ability to incite emotional…

  14. Environmental Science: Activities with Plants of the Southwest.

    ERIC Educational Resources Information Center

    Hackley, Sharon; Hackley, Mike

    In this book for students of all ages, the author introduces unusual recipe ideas for the prickly, odd, and pestiferous plants of the American southwestern desert. Students are involved in cooking activities designed to spark interest in ecology, trigger logical thinking, utilize math skills, and build sound environmental concepts. Care was taken…

  15. Investigation of Potential Triggered Tremor in Latin America and the Caribbean

    NASA Astrophysics Data System (ADS)

    Gonzalez-Huizar, H.; Velasco, A. A.; Peng, Z.

    2012-12-01

    Recent observations have shown that seismic waves generate transient stresses capable of triggering earthquakes and tectonic (or non-volcanic) tremor far away from the original earthquake source. However, the mechanisms behind remotely triggered seismicity still remain unclear. Triggered tremor signals can be particularly useful in investigating remote triggering processes, since in many cases, the tremor pulses are very clearly modulated by the passing surface waves. The temporal stress changes (magnitude and orientation) caused by seismic waves at the tremor source region can be calculated and correlated with tremor pulses, which allows for exploring the stresses involved in the triggering process. Some observations suggest that triggered and ambient tremor signals are generated under similar physical conditions; thus, investigating triggered tremor might also provide important clues on how and under what conditions ambient tremor signals generate. In this work we present some of the results and techniques we employ in the research of potential cases of triggered tectonic tremor in Latin America and the Caribbean. This investigation includes: (1) the triggered tremor detection, with the use of specific signal filters; (2) localization of the sources, using uncommon techniques like time reversal signals; (3) and the analysis of the stress conditions under which they are generated, by modeling the triggering waves related dynamic stress. Our results suggest that tremor can be dynamically triggered by both Love and Rayleigh waves and in broad variety of tectonic environments depending strongly on the dynamic stress amplitude and orientation. Investigating remotely triggered seismicity offers the opportunity to improve our knowledge about deformation mechanisms and the physics of rupture.

  16. Conditions for addressing environmental determinants of health behavior in intersectoral policy networks: A fuzzy set Qualitative Comparative Analysis.

    PubMed

    Peters, D T J M; Verweij, S; Grêaux, K; Stronks, K; Harting, J

    2017-12-01

    Improving health requires changes in the social, physical, economic and political determinants of health behavior. For the realization of policies that address these environmental determinants, intersectoral policy networks are considered necessary for the pooling of resources to implement different policy instruments. However, such network diversity may increase network complexity and therefore hamper network performance. Network complexity may be reduced by network management and the provision of financial resources. This study examined whether network diversity - amidst the other conditions - is indeed needed to address environmental determinants of health behavior. We included 25 intersectoral policy networks in Dutch municipalities aimed at reducing overweight, smoking, and alcohol/drugs abuse. For our fuzzy set Qualitative Comparative Analysis we used data from three web-based surveys among (a) project leaders regarding network diversity and size (n = 38); (b) project leaders and project partners regarding management (n = 278); and (c) implementation professionals regarding types of environmental determinants addressed (n = 137). Data on budgets were retrieved from project application forms. Contrary to their intentions, most policy networks typically addressed personal determinants. If the environment was addressed too, it was mostly the social environment. To address environmental determinants of health behavior, network diversity (>50% of the actors are non-public health) was necessary in networks that were either small (<16 actors) or had small budgets (<€183,172), when both were intensively managed. Irrespective of network diversity, environmental determinants also were addressed by small networks with large budgets, and by large networks with small budgets, when both provided network management. We conclude that network diversity is important - although not necessary - for resource pooling to address environmental determinants of health behavior

  17. Climate‐Dependent Heat‐Triggered Opening Mechanism of Banksia Seed Pods

    PubMed Central

    Schoeppler, Vanessa; Merritt, David J.; Best, Christine; Maire, Eric; Adrien, Jérôme; Spaeker, Oliver; Janssen, Nils; Gladisch, Johannes; Gierlinger, Notburga; Miller, Ben P.; Fratzl, Peter

    2017-01-01

    Abstract Heat‐triggered fruit opening and delayed release of mature seeds are widespread among plants in fire‐prone ecosystems. Here, the material characteristics of the seed‐containing follicles of Banksia attenuata (Proteaceae), which open in response to heat frequently caused by fire, are investigated. Material analysis reveals that long‐term dimensional stability and opening temperatures of follicles collected across an environmental gradient increase as habitats become drier, hotter, and more fire prone. A gradual increase in the biaxial curvature of the hygroscopic valves provides the follicles in the driest region with the highest flexural rigidity. The irreversible deformation of the valves for opening is enabled via a temperature‐dependent reduction of the elastic modulus of the innermost tissue layer, which then allows releasing the stresses previously generated by shrinkage of the fiber bundles in the adjacent layer during follicle drying. These findings illustrate the level of sophistication by which this species optimizes its fruit opening mechanism over a large distribution range with varying environmental conditions, and may not only have great relevance for developing biomimetic actuators, but also for elucidating the species' capacity to cope with climatic changes. PMID:29375977

  18. Environmental and hydrologic setting of the Ozark Plateaus study unit, Arkansas, Kansas, Missouri, and Oklahoma

    USGS Publications Warehouse

    Adamski, James C.; Petersen, James C.; Freiwald, David A.; Davis, Jerri V.

    1995-01-01

    The environmental and hydrologic setting of the Ozark Plateaus National Water-Quality Assessment (NAWQA) study unit and the factors that affect water quality are described in this report. The primary natural and cultural features that affect water- quality characteristics and the potential for future water-quality problems are described. These environmental features include climate, physio- graphy, geology, soils, population, land use, water use, and surface- and ground-water flow systems. The study-unit area is approximately 47,600 square miles and includes most of the Ozark Plateaus Province and parts of the adjacent Osage Plains and Mississippi Alluvial Plain in parts of Arkansas, Kansas, Missouri, and Oklahoma. The geology is characterized by basement igneous rocks overlain by a thick sequence of dolomites, limestones, sandstones, and shales of Paleozoic age. Land use in the study unit is predominantly pasture and forest in the southeastern part, and pasture and cropland in the northwestern part. All or part of the White, Neosho-lllinois, Osage, Gasconade, Meramec, St. Francis, and Black River Basins are within the study unit. Streams in the Boston Mountains contain the least mineralized water, and those in the Osage Plains contain the most mineralized water. The study unit contains eight hydrogeologic units including three major aquifers--the Springfield Plateau, Ozark, and St. Francois aquifers. Streams and aquifers in the study unit generally contain calcium or calcium-magnesium bicarbonate waters. Ground- and surface-water interactions are greatest in the Salem and Springfield Plateaus and least in the Boston Mountains and Osage Plains. Geology, land use, and population probably are the most important environmental factors that affect water quality.

  19. Development and Pilot Testing of a Bilingual Environmental Health Assessment Tool to Promote Asthma-friendly Childcares.

    PubMed

    Evans-Agnew, Robin A; Postma, Julie; Camacho, Ariana Ochoa; Hershberg, Rachel M; Trujilio, Elsa; Tinajera, Maria

    2018-01-01

    Childhood marks the highest risk for allergic sensitization to asthma triggers. Hispanic/Latino children are at higher risk for hospitalization for asthma than non-Hispanic White children. Childcare providers lack knowledge about reducing asthma triggers. The purpose of this paper is to describe a community-based participatory research (CBPR) initiative aimed at developing and pilot testing a bilingual walk-through assessment tool for asthma-friendly childcare environments. Ten Latina mothers of children with asthma living in the Pacific Northwest collaborated with research partners to develop and pilot test a Childcare Environmental Health (CEH) assessment walk-through survey.Results and Lessons Learned: The women innovated the survey with photography and structural examinations of stress and provision of basic needs. The survey tool identified environmental threats to asthma in all three childcares surveyed. Parents are well-positioned to build trust with childcare providers, assess asthma triggers, and recommend practical mitigation strategies.

  20. A Randomized Clinical Trial of Red Blood Cell Transfusion Triggers in Cardiac Surgery.

    PubMed

    Koch, Colleen G; Sessler, Daniel I; Mascha, Edward J; Sabik, Joseph F; Li, Liang; Duncan, Andra I; Zimmerman, Nicole M; Blackstone, Eugene H

    2017-10-01

    Class I evidence supporting a threshold for transfusion in the cardiac surgical setting is scarce. We randomly allocated patients to a transfusion hematocrit trigger of 24% versus 28% to compare morbidity, mortality, and resource use. From March 2007 to August 2014, two centers randomly assigned 722 adults undergoing coronary artery bypass graft surgery or valve procedures to a 24% hematocrit trigger (n = 363, low group) or 28% trigger (n = 354, high group). One unit of red blood cells was transfused if the hematocrit fell below the designated threshold. The primary endpoint was a composite of postoperative morbidities and mortality. Treatment effect was primarily assessed using an average relative effect generalized estimating equation model. At the second planned interim analysis, the a priori futility boundary was crossed, and the study was stopped. There was no detected treatment effect on the composite outcome (average relative effect odds ratio, low versus high, 0.86, 95% confidence interval: 0.29 to 2.54, p = 0.71). However, the low group received fewer red blood cell transfusions than the high group (54% versus 75%, p < 0.001), mostly administered in the operating room (low group, 112 [31%]; high group, 208 [59%]), followed by intensive care unit (low, 105 [31%]; high, 115 [34%]) and floor (low, 41 [12%]; high, 42 [13%]). The low group was exposed to lower hematocrits: median before transfusion, 22% (Q1 = 21%, Q3 = 23%) versus 24% (Q1 = 22%, Q3 = 25%). Negative exposures differed between treatment groups, with lower hematocrit in the 24% trigger group and more red blood cells used in the 28% group, but adverse outcomes did not differ. Because red blood cell use was less with a 24% trigger without adverse effects, our randomized trial results support aggressive blood conservation efforts in cardiac surgery. Copyright © 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  1. Natural and unnatural triggers of myocardial infarction.

    PubMed

    Kloner, Robert A

    2006-01-01

    Previous analyses have suggested that factors that stimulate the sympathetic nervous system and catecholamine release can trigger acute myocardial infarction. The wake-up time, Mondays, winter season, physical exertion, emotional upset, overeating, lack of sleep, cocaine, marijuana, anger, and sexual activity are some of the more common triggers. Certain natural disasters such as earthquakes and blizzards have also been associated with an increase in cardiac events. Certain unnatural triggers may play a role including the Holiday season. Holiday season cardiac events peak on Christmas and New Year. A number of hypotheses have been raised to explain the increase in cardiac events during the holidays, including overeating, excessive use of salt and alcohol, exposure to particulates, from fireplaces, a delay in seeking medical help, anxiety or depression related to the holidays, and poorer staffing of health care facilities at this time. War has been associated with an increase in cardiac events. Data regarding an increase in cardiac events during the 9/11 terrorist attack have been mixed. Understanding the cause of cardiovascular triggers will help in developing potential therapies.

  2. Environmental change challenges decision-making during post-market environmental monitoring of transgenic crops.

    PubMed

    Sanvido, Olivier; Romeis, Jörg; Bigler, Franz

    2011-12-01

    The ability to decide what kind of environmental changes observed during post-market environmental monitoring of genetically modified (GM) crops represent environmental harm is an essential part of most legal frameworks regulating the commercial release of GM crops into the environment. Among others, such decisions are necessary to initiate remedial measures or to sustain claims of redress linked to environmental liability. Given that consensus on criteria to evaluate 'environmental harm' has not yet been found, there are a number of challenges for risk managers when interpreting GM crop monitoring data for environmental decision-making. In the present paper, we argue that the challenges in decision-making have four main causes. The first three causes relate to scientific data collection and analysis, which have methodological limits. The forth cause concerns scientific data evaluation, which is controversial among the different stakeholders involved in the debate on potential impacts of GM crops on the environment. This results in controversy how the effects of GM crops should be valued and what constitutes environmental harm. This controversy may influence decision-making about triggering corrective actions by regulators. We analyse all four challenges and propose potential strategies for addressing them. We conclude that environmental monitoring has its limits in reducing uncertainties remaining from the environmental risk assessment prior to market approval. We argue that remaining uncertainties related to adverse environmental effects of GM crops would probably be assessed in a more efficient and rigorous way during pre-market risk assessment. Risk managers should acknowledge the limits of environmental monitoring programmes as a tool for decision-making.

  3. Influence of different interfaces on synchrony during pressure support ventilation in a pediatric setting: a bench study.

    PubMed

    Conti, Giorgio; Gregoretti, Cesare; Spinazzola, Giorgia; Festa, Olimpia; Ferrone, Giuliano; Cipriani, Flora; Rossi, Marco; Piastra, Marco; Costa, Roberta

    2015-04-01

    In adults and children, patient-ventilator synchrony is strongly dependent on both the ventilator settings and interface used in applying positive pressure to the airway. The aim of this bench study was to determine whether different interfaces and ventilator settings may influence patient-ventilator interaction in pediatric models of normal and mixed obstructive and restrictive respiratory conditions. A test lung, connected to a pediatric mannequin using different interfaces (endotracheal tube [ETT], face mask, and helmet), was ventilated in pressure support ventilation mode testing 2 ventilator settings (pressurization time [Timepress]50%/cycling-off flow threshold [Trexp]25%, Timepress80%/Trexp60%), randomly applied. The test lung was set to simulate one pediatric patient with a healthy respiratory system and another with a mixed obstructive and restricted respiratory condition, at different breathing frequencies (f) (30, 40, and 50 breaths/min). We measured inspiratory trigger delay, pressurization time, expiratory trigger delay, and time of synchrony. At each breathing frequency, the helmet showed the longest inspiratory trigger delay compared with the ETT and face mask. At f30, the ETT had a reduced Tpress. The helmet had the shortest Tpress in the simulated child with a mixed obstructive and restricted respiratory condition, at f40 during Timepress50%/Trexp25% and at f50 during Timepress80%/Trexp60%. In the simulated child with a normal respiratory condition, the ETT presented the shortest Tpress value at f50 during Timepress80%/Trexp60%. Concerning the expiratory trigger delay, the helmet showed the best interaction at f30, but the worst at f40 and at f50. The helmet showed the shortest time of synchrony during all ventilator settings. The choice of the interface can influence patient-ventilator synchrony in a pediatric model breathing at increased f, thus making it more difficult to set the ventilator, particularly during noninvasive ventilation. The

  4. Adult Learning in Free-Choice, Environmental Settings: What Makes It Different?

    ERIC Educational Resources Information Center

    Heimlich, Joe E.; Horr, E. Elaine T.

    2010-01-01

    Environmental learning, or how individuals make sense and meaning about nature, the environment, ecology, and environmental issues, is best understood as lifelong, life-wide, and life-deep (Banks and others, 2007). Lifelong learning refers to acquisition of skills, competencies, attitudes, and knowledge over time; life-wide is learning across…

  5. Influence of uncertain identification of triggering rainfall on the assessment of landslide early warning thresholds

    NASA Astrophysics Data System (ADS)

    Peres, David J.; Cancelliere, Antonino; Greco, Roberto; Bogaard, Thom A.

    2018-03-01

    Uncertainty in rainfall datasets and landslide inventories is known to have negative impacts on the assessment of landslide-triggering thresholds. In this paper, we perform a quantitative analysis of the impacts of uncertain knowledge of landslide initiation instants on the assessment of rainfall intensity-duration landslide early warning thresholds. The analysis is based on a synthetic database of rainfall and landslide information, generated by coupling a stochastic rainfall generator and a physically based hydrological and slope stability model, and is therefore error-free in terms of knowledge of triggering instants. This dataset is then perturbed according to hypothetical reporting scenarios that allow simulation of possible errors in landslide-triggering instants as retrieved from historical archives. The impact of these errors is analysed jointly using different criteria to single out rainfall events from a continuous series and two typical temporal aggregations of rainfall (hourly and daily). The analysis shows that the impacts of the above uncertainty sources can be significant, especially when errors exceed 1 day or the actual instants follow the erroneous ones. Errors generally lead to underestimated thresholds, i.e. lower than those that would be obtained from an error-free dataset. Potentially, the amount of the underestimation can be enough to induce an excessive number of false positives, hence limiting possible landslide mitigation benefits. Moreover, the uncertain knowledge of triggering rainfall limits the possibility to set up links between thresholds and physio-geographical factors.

  6. Stimulus conflict triggers behavioral avoidance.

    PubMed

    Dignath, David; Eder, Andreas B

    2015-12-01

    According to a recent extension of the conflict-monitoring theory, conflict between two competing response tendencies is registered as an aversive event and triggers a motivation to avoid the source of conflict. In the present study, we tested this assumption. Over five experiments, we examined whether conflict is associated with an avoidance motivation and whether stimulus conflict or response conflict triggers an avoidance tendency. Participants first performed a color Stroop task. In a subsequent motivation test, participants responded to Stroop stimuli with approach- and avoidance-related lever movements. These results showed that Stroop-conflict stimuli increased the frequency of avoidance responses in a free-choice motivation test, and also increased the speed of avoidance relative to approach responses in a forced-choice test. High and low proportions of response conflict in the Stroop task had no effect on avoidance in the motivation test. Avoidance of conflict was, however, obtained even with new conflict stimuli that had not been presented before in a Stroop task, and when the Stroop task was replaced with an unrelated filler task. Taken together, these results suggest that stimulus conflict is sufficient to trigger avoidance.

  7. Disambiguating Syntactic Triggers

    ERIC Educational Resources Information Center

    Sakas, William Gregory; Fodor, Janet Dean

    2012-01-01

    We present data from an artificial language domain that suggest new contributions to the theory of syntactic triggers. Whether a learning algorithm is capable of matching the achievements of child learners depends in part on how much parametric ambiguity there is in the input. For practical reasons this cannot be established for the domain of all…

  8. The green choices project: integrating environmental health education into reproductive health care settings.

    PubMed

    Worthington, Sandra; Armstrong, Kay; Debevec, Elie

    2010-01-01

    A national reproductive health organization developed the Green Choices project to educate staff and clients about how to live in healthier environments by reducing potentially harmful environmental exposures to toxicants. An advisory group, comprised of experts in environmental and reproductive health and literacy, defined the project's scope and common environmental exposures to address. The following educational materials were developed: an online staff environmental health 101 curriculum, an environmental health assessment tool for clients to identify their potential risks, and information sheets for each environmental exposure that described potential risks and ways to reduce risks. Beta-testing methods included baseline and follow-up surveys, one-on-one interviews, focus groups, and recommendations from experts. Staff and client feedback on the educational materials resulted in increased clarity, sensitivity, relevancy, and appeal. Environmental health experts ensured accuracy of information, and reading experts lowered the reading level from 12th to 6th grade. A campaign to disseminate environmental health information and educational materials nationally is under way.

  9. Small-scale impacts as potential trigger for landslides on small Solar system bodies

    NASA Astrophysics Data System (ADS)

    Hofmann, Marc; Sierks, Holger; Blum, Jürgen

    2017-07-01

    We conducted a set of experiments to investigate whether millimetre-sized impactors impinging on a granular material at several m s-1 are able to trigger avalanches on small, atmosphereless planetary bodies. These experiments were carried out at the Zentrum für angewandte Raumfahrttechnologie und Mikrogravitation (ZARM) drop tower facility in Bremen, Germany to facilitate a reduced gravity environment. Additional data were gathered at Earth gravity levels in the laboratory. As sample materials we used a ground Howardites, Eucrites and Diogenites (HED) meteorite and the Johnson Space Center (JSC) Mars-1 Martian soil simulant. We found that this type of small-scale impact can trigger avalanches with a moderate probability, if the target material is tilted to an angle close to the angle of repose. We additionally simulated a small-scale impact using the discrete element method code esys-particle. These simulations show that energy transfer from impactor to the target material is most efficient at low- and moderate-impactor inclinations and the transferred energy is retained in particles close to the surface due to a rapid dissipation of energy in lower material layers driven by inelastic collisions. Through Monte Carlo simulations we estimate the time-scale on which small-scale impacts with the observed characteristics will trigger avalanches covering all steep slopes on the surface of a small planetary body to be of the order 105 yr.

  10. The CMS High-Level Trigger

    NASA Astrophysics Data System (ADS)

    Covarelli, R.

    2009-12-01

    At the startup of the LHC, the CMS data acquisition is expected to be able to sustain an event readout rate of up to 100 kHz from the Level-1 trigger. These events will be read into a large processor farm which will run the "High-Level Trigger" (HLT) selection algorithms and will output a rate of about 150 Hz for permanent data storage. In this report HLT performances are shown for selections based on muons, electrons, photons, jets, missing transverse energy, τ leptons and b quarks: expected efficiencies, background rates and CPU time consumption are reported as well as relaxation criteria foreseen for a LHC startup instantaneous luminosity.

  11. Advantages of video trigger in problem-based learning.

    PubMed

    Chan, Lap Ki; Patil, Nivritti G; Chen, Julie Y; Lam, Jamie C M; Lau, Chak S; Ip, Mary S M

    2010-01-01

    Traditionally, paper cases are used as 'triggers' to stimulate learning in problem-based learning (PBL). However, video may be a better medium because it preserves the original language, encourages the active extraction of information, avoids depersonalization of patients and allows direct observation of clinical consultations. In short, it exposes the students to the complexity of actual clinical problems. The study aims to find out whether students and facilitators who are accustomed to paper cases would prefer video triggers or paper cases and the reasons for their preference. After students and facilitators had completed a video PBL tutorial, their responses were measured by a structured questionnaire using a modified Likert scale. A total of 257 students (92%) and 26 facilitators (100%) responded. The majority of students and facilitators considered that using video triggers could enhance the students' observational powers and clinical reasoning, help them to integrate different information and better understand the cases and motivate them to learn. They found PBL using video triggers more interesting and preferred it to PBL using paper cases. Video triggers are preferred by both students and facilitators over paper cases in PBL.

  12. Graphics Processors in HEP Low-Level Trigger Systems

    NASA Astrophysics Data System (ADS)

    Ammendola, Roberto; Biagioni, Andrea; Chiozzi, Stefano; Cotta Ramusino, Angelo; Cretaro, Paolo; Di Lorenzo, Stefano; Fantechi, Riccardo; Fiorini, Massimiliano; Frezza, Ottorino; Lamanna, Gianluca; Lo Cicero, Francesca; Lonardo, Alessandro; Martinelli, Michele; Neri, Ilaria; Paolucci, Pier Stanislao; Pastorelli, Elena; Piandani, Roberto; Pontisso, Luca; Rossetti, Davide; Simula, Francesco; Sozzi, Marco; Vicini, Piero

    2016-11-01

    Usage of Graphics Processing Units (GPUs) in the so called general-purpose computing is emerging as an effective approach in several fields of science, although so far applications have been employing GPUs typically for offline computations. Taking into account the steady performance increase of GPU architectures in terms of computing power and I/O capacity, the real-time applications of these devices can thrive in high-energy physics data acquisition and trigger systems. We will examine the use of online parallel computing on GPUs for the synchronous low-level trigger, focusing on tests performed on the trigger system of the CERN NA62 experiment. To successfully integrate GPUs in such an online environment, latencies of all components need analysing, networking being the most critical. To keep it under control, we envisioned NaNet, an FPGA-based PCIe Network Interface Card (NIC) enabling GPUDirect connection. Furthermore, it is assessed how specific trigger algorithms can be parallelized and thus benefit from a GPU implementation, in terms of increased execution speed. Such improvements are particularly relevant for the foreseen Large Hadron Collider (LHC) luminosity upgrade where highly selective algorithms will be essential to maintain sustainable trigger rates with very high pileup.

  13. The LUX experiment - trigger and data acquisition systems

    NASA Astrophysics Data System (ADS)

    Druszkiewicz, Eryk

    2013-04-01

    The Large Underground Xenon (LUX) detector is a two-phase xenon time projection chamber designed to detect interactions of dark matter particles with the xenon nuclei. Signals from the detector PMTs are processed by custom-built analog electronics which provide properly shaped signals for the trigger and data acquisition (DAQ) systems. During calibrations, both systems must be able to handle high rates and have large dynamic ranges; during dark matter searches, maximum sensitivity requires low thresholds. The trigger system uses eight-channel 64-MHz digitizers (DDC-8) connected to a Trigger Builder (TB). The FPGA cores on the digitizers perform real-time pulse identification (discriminating between S1 and S2-like signals) and event localization. The TB uses hit patterns, hit maps, and maximum response detection to make trigger decisions, which are reached within few microseconds after the occurrence of an event of interest. The DAQ system is comprised of commercial digitizers with customized firmware. Its real-time baseline suppression allows for a maximum event acquisition rate in excess of 1.5 kHz, which results in virtually no deadtime. The performance of the trigger and DAQ systems during the commissioning runs of LUX will be discussed.

  14. Interactive Teaching about Landslides and Triggered Landslide Events

    NASA Astrophysics Data System (ADS)

    Taylor, Faith E.; Malamud, Bruce D.

    2015-04-01

    When we think of a landslide (mass wasting), both the public and scientists often envisage an individual movement of earth material down a slope. Yet, landslides often occur not as individuals, but as parts of a triggered landslide event. This is where a trigger (e.g., an earthquake or heavy rainfall) results in up to tens of thousands of landslides in a region in the minutes to days after the trigger. The sum of the impacts of these landslides may be greater than individual parts. This interactive Prezi poster will present ideas for innovative demonstrations, teaching practicals and projects, ranging from low-cost low-tech to more advanced digital methods, to communicate the ideas of landslides and triggered landslide events to the public and students. We will give live hands-on demonstrations and welcome discussions with other scientists to share ideas and best practices. This paper is aimed at those in secondary school/university education and the public sector looking for examples to interest and inform their respective audiences about landslides, triggered landslide events, and the importance and implications of considering landslides not just as individuals, but as populations.

  15. Investigations related to scientific deep drilling to study reservoir-triggered earthquakes at Koyna, India

    NASA Astrophysics Data System (ADS)

    Gupta, Harsh; Purnachandra Rao, N.; Roy, Sukanta; Arora, Kusumita; Tiwari, V. M.; Patro, Prasanta K.; Satyanarayana, H. V. S.; Shashidhar, D.; Mallika, K.; Akkiraju, Vyasulu V.; Goswami, Deepjyoti; Vyas, Digant; Ravi, G.; Srinivas, K. N. S. S. S.; Srihari, M.; Mishra, S.; Dubey, C. P.; Raju, D. Ch. V.; Borah, Ujjal; Chinna Reddy, K.; Babu, Narendra; Rohilla, Sunil; Dhar, Upasana; Sen, Mrinal; Bhaskar Rao, Y. J.; Bansal, B. K.; Nayak, Shailesh

    2015-09-01

    Artificial water reservoir-triggered earthquakes have continued at Koyna in the Deccan Traps province, India, since the impoundment of the Shivaji Sagar reservoir in 1962. Existing models, to comprehend the genesis of triggered earthquakes, suffer from lack of observations in the near field. To investigate further, scientific deep drilling and setting up a fault zone observatory at depth of 5-7 km is planned in the Koyna area. Prior to undertaking deep drilling, an exploratory phase of investigations has been launched to constrain subsurface geology, structure and heat flow regime in the area that provide critical inputs for the design of the deep borehole observatory. Two core boreholes drilled to depths of 1,522 and 1,196 m have penetrated the Deccan Traps and sampled the granitic basement in the region for the first time. Studies on cores provide new and direct information regarding the thickness of the Deccan Traps, the absence of infra-Trappean sediments and the nature of the underlying basement rocks. Temperatures estimated at a depth of 6 km in the area, made on the basis of heat flow and thermal properties data sets, do not exceed 150 °C. Low-elevation airborne gravity gradient and magnetic data sets covering 5,012 line km, together with high-quality magnetotelluric data at 100 stations, provide both regional information about the thickness of the Deccan Traps and the occurrence of localized density heterogeneities and anomalous conductive zones in the vicinity of the hypocentral zone. Acquisition of airborne LiDAR data to obtain a high-resolution topographic model of the region has been completed over an area of 1,064 km2 centred on the Koyna seismic zone. Seismometers have been deployed in the granitic basement inside two boreholes and are planned in another set of six boreholes to obtain accurate hypocentral locations and constrain the disposition of fault zones.

  16. Correspondence between discrete and continuous models of excitable media: trigger waves

    NASA Technical Reports Server (NTRS)

    Chernyak, Y. B.; Feldman, A. B.; Cohen, R. J.

    1997-01-01

    We present a theoretical framework for relating continuous partial differential equation (PDE) models of excitable media to discrete cellular automata (CA) models on a randomized lattice. These relations establish a quantitative link between the CA model and the specific physical system under study. We derive expressions for the CA model's plane wave speed, critical curvature, and effective diffusion constant in terms of the model's internal parameters (the interaction radius, excitation threshold, and time step). We then equate these expressions to the corresponding quantities obtained from solution of the PDEs (for a fixed excitability). This yields a set of coupled equations with a unique solution for the required CA parameter values. Here we restrict our analysis to "trigger" wave solutions obtained in the limiting case of a two-dimensional excitable medium with no recovery processes. We tested the correspondence between our CA model and two PDE models (the FitzHugh-Nagumo medium and a medium with a "sawtooth" nonlinear reaction source) and found good agreement with the numerical solutions of the PDEs. Our results suggest that the behavior of trigger waves is actually controlled by a small number of parameters.

  17. Occupational and Environmental Contributions to Chronic Cough in Adults: Chest Expert Panel Report.

    PubMed

    Tarlo, Susan M; Altman, Kenneth W; Oppenheimer, John; Lim, Kaiser; Vertigan, Anne; Prezant, David; Irwin, Richard S

    2016-10-01

    In response to occupational and environmental exposures, cough can be an isolated symptom reflecting exposure to an irritant with little physiological consequence, or it can be a manifestation of more significant disease. This document reviews occupational and environmental contributions to chronic cough in adults, focusing on aspects not previously covered in the 2006 ACCP Cough Guideline or our more recent systematic review, and suggests an approach to investigation of these factors when suspected. MEDLINE and TOXLINE literature searches were supplemented by articles identified by the cough panel occupational and environmental subgroup members, to identify occupational and environmental aspects of chronic cough not previously covered in the 2006 ACCP Cough Guideline. Based on the literature reviews and the Delphi methodology, the cough panel occupational and environmental subgroup developed guideline suggestions that were approved after review and voting by the full cough panel. The literature review identified relevant articles regarding: mechanisms; allergic environmental causes; chronic cough and the recreational and involuntary inhalation of tobacco and marijuana smoke; nonallergic environmental triggers; laryngeal syndromes; and occupational diseases and exposures. Consensus-based statements were developed for the approach to diagnosis due to a lack of strong evidence from published literature. Despite increased understanding of cough related to occupational and environmental triggers, there remains a gap between the recommended assessment of occupational and environmental causes of cough and the reported systematic assessment of these factors. There is a need for further documentation of occupational and environmental causes of cough in the future. Copyright © 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

  18. Cosmetics-triggered percutaneous remote control of transgene expression in mice.

    PubMed

    Wang, Hui; Ye, Haifeng; Xie, Mingqi; Daoud El-Baba, Marie; Fussenegger, Martin

    2015-08-18

    Synthetic biology has significantly advanced the rational design of trigger-inducible gene switches that program cellular behavior in a reliable and predictable manner. Capitalizing on genetic componentry, including the repressor PmeR and its cognate operator OPmeR, that has evolved in Pseudomonas syringae pathovar tomato DC3000 to sense and resist plant-defence metabolites of the paraben class, we have designed a set of inducible and repressible mammalian transcription-control devices that could dose-dependently fine-tune transgene expression in mammalian cells and mice in response to paraben derivatives. With an over 60-years track record as licensed preservatives in the cosmetics industry, paraben derivatives have become a commonplace ingredient of most skin-care products including shower gels, cleansing toners and hand creams. As parabens can rapidly reach the bloodstream of mice following topical application, we used this feature to percutaneously program transgene expression of subcutaneous designer cell implants using off-the-shelf commercial paraben-containing skin-care cosmetics. The combination of non-invasive, transdermal and orthogonal trigger-inducible remote control of transgene expression may provide novel opportunities for dynamic interventions in future gene and cell-based therapies. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  19. Melding Environmental Education and Creative Learning in Elementary and Middle-school Settings

    NASA Astrophysics Data System (ADS)

    Jain, S.; Baker, T.; Crofton-Macdonald, J.; Scott, M.

    2017-12-01

    Teaching environmental topics, such as sustainability and ecosystem management, to students through the lens of computational thinking provides unique educational opportunities. Environmental topics are an excellent source for multidisciplinary learning, as questions concerning human well-being, environmental policy, science, and mathematics can naturally be incorporated into educational discussions and activities. The use of computational modeling allows students to critically reason about and explore environmental concepts by envisioning complexity, and asking and investigating a series of "what if" questions. Students can furthermore reflect on their own relationship with their local ecology. For the past five years, we have tested and developed activities for middle school students. Through in-class activities, workshop, and summer clubs, we have explored these ideas. We plan to present examples from our work and a tentative framework for a new approach to environmental education, one reinforced by computational thinking and creative learning.

  20. Self-triggering superconducting fault current limiter

    DOEpatents

    Yuan, Xing [Albany, NY; Tekletsadik, Kasegn [Rexford, NY

    2008-10-21

    A modular and scaleable Matrix Fault Current Limiter (MFCL) that functions as a "variable impedance" device in an electric power network, using components made of superconducting and non-superconducting electrically conductive materials. The matrix fault current limiter comprises a fault current limiter module that includes a superconductor which is electrically coupled in parallel with a trigger coil, wherein the trigger coil is magnetically coupled to the superconductor. The current surge doing a fault within the electrical power network will cause the superconductor to transition to its resistive state and also generate a uniform magnetic field in the trigger coil and simultaneously limit the voltage developed across the superconductor. This results in fast and uniform quenching of the superconductors, significantly reduces the burnout risk associated with non-uniformity often existing within the volume of superconductor materials. The fault current limiter modules may be electrically coupled together to form various "n" (rows).times."m" (columns) matrix configurations.

  1. [Triggers of bulimia and compulsion attacks: validation of the "Start" questionnaire].

    PubMed

    Rigaud, D; Jiang, T; Pennacchio, H; Brémont, M; Perrin, D

    2014-09-01

    patients, as well as sadness (61%), feeling of powerlessness (62%), inefficiency (73%) and depressive state (71%). Flashback from traumatism (sexual trauma in 17% of the patients) was a strong trigger of binges more often in BPAN and BED (44%) than in BN (23%; P<0.05). The binge eating was painful (and "not at all a pleasure") in 69% of the patients, but could also be a relaxing behavior in 31% of the patients, more often in the BED (43%) than in the BPAN patients (20%; P<0.05). The binge eating behavior was quoted as obsessive in 63% of BPAN, 92% of BN and only 34% of BED patients (P<0.001). The patients said that they were unable to avoid the binge (76% of the patients), more often in BPAN and BN than in BED patients (P<0.01). As a whole, 62% of BPAN, 89% of BN and only 4 % of BED patients (P<0.05) were unable to avoid purging (vomiting). In 12% of the cases, there was a pleasure felt when binging. For the other patients, shame, filth and incapacity were the feelings related to binges in 58% of the BPAN, 45% of BN and 43% of BED patients (P<0.04). The global score of addiction (zero=not addicted, 10=very addicted) was 8.56+1.2 in BPAN, 8.42+1.5 in BN and 6.74+1.1 in BED patients (NS between BPAN and BN; P<0.01 between BPAN and BN on the one hand and BED on the other). The present study has demonstrated the usefulness of the Start questionnaire. It also evidences the key role of intrinsic factors, both metabolic and emotional, as strong triggers for binge eating episodes in BPAN, BN and BED. It has also demonstrated the role of environmental determinants. Copyright © 2013 L’Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

  2. Towards a Systematic Search for Triggered Seismic Events in the USA

    NASA Astrophysics Data System (ADS)

    Tang, V.; Chao, K.; Van der Lee, S.

    2017-12-01

    Dynamic triggering of small earthquakes and tectonic tremor by small stress variations associated with passing surface waves from large-magnitude teleseismic earthquakes have been observed in seismically active regions in the western US. Local stress variations as small as 5 10 kPa can suffice to advance slip on local faults. Observations of such triggered events share certain distinct characteristics. With an eye towards an eventual application of machine learning, we began a systematic search for dynamically triggered seismic events in the USA that have these characteristics. Such a systematic survey has the potential to help us to better understand the fundamental process of dynamic triggering and hazards implied by it. Using visual inspection on top of timing and frequency based selection criteria for these seismic phenomena, our search yielded numerous false positives, indicating the challenge posed by moving from ad-hoc observations of dynamic triggering to a systematic search that also includes a catalog of non-triggering, even when sufficient stress variations are supplied. Our search includes a dozen large earthquakes that occurred during the tenure of USArray. One of these earthquakes (11 April 2012 Mw8.6 Sumatra), for example, was observed by USArray-TA stations in the Midwest and other station networks (such as PB and UW), and yielded candidate-triggered events at 413 stations. We kept 79 of these observations after closer visual inspection of the observed events suggested distinct P and S arrivals from a local earthquake, or a tremor modulation with the same period as the surface wave, among other criteria. We confirmed triggered seismic events in 63 stations along the western plate boundary where triggered events have previously been observed. We also newly found triggered tremor sources in eastern Oregon and Yellowstone, and candidate-triggered earthquake sources in New Mexico and Minnesota. Learning whether 14 of remaining candidates are confirmed

  3. Stimulus Set Meaningfulness and Neurophysiological Differentiation: A Functional Magnetic Resonance Imaging Study

    PubMed Central

    Boly, Melanie; Sasai, Shuntaro; Gosseries, Olivia; Oizumi, Masafumi; Casali, Adenauer; Massimini, Marcello; Tononi, Giulio

    2015-01-01

    A meaningful set of stimuli, such as a sequence of frames from a movie, triggers a set of different experiences. By contrast, a meaningless set of stimuli, such as a sequence of ‘TV noise’ frames, triggers always the same experience—of seeing ‘TV noise’—even though the stimuli themselves are as different from each other as the movie frames. We reasoned that the differentiation of cortical responses underlying the subject’s experiences, as measured by Lempel-Ziv complexity (incompressibility) of functional MRI images, should reflect the overall meaningfulness of a set of stimuli for the subject, rather than differences among the stimuli. We tested this hypothesis by quantifying the differentiation of brain activity patterns in response to a movie sequence, to the same movie scrambled in time, and to ‘TV noise’, where the pixels from each movie frame were scrambled in space. While overall cortical activation was strong and widespread in all conditions, the differentiation (Lempel-Ziv complexity) of brain activation patterns was correlated with the meaningfulness of the stimulus set, being highest in the movie condition, intermediate in the scrambled movie condition, and minimal for ‘TV noise’. Stimulus set meaningfulness was also associated with higher information integration among cortical regions. These results suggest that the differentiation of neural responses can be used to assess the meaningfulness of a given set of stimuli for a given subject, without the need to identify the features and categories that are relevant to the subject, nor the precise location of selective neural responses. PMID:25970444

  4. Design and investigation of a multichannel laser-triggered vacuum switch

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fan, Wenfang, E-mail: fwf1990@126.com; He, Zhenghao; Mao, Xiaopo

    2016-03-15

    A laser-triggered vacuum switch (LTVS) is an advanced closing switch with nanosecond delay and jitter. In order to enhance hold-off voltage and extend the service lifetime of an LTVS, we designed a multichannel laser-triggered vacuum switch (MLTVS) utilizing a cone-shaped target electrode placed on the cathode platform. The fabrication and testing of the MLTVS is described in this paper. Experimental results show that the working voltage of the MLTVS with a gap distance of 12 mm is from 30 V to 20 kV. The threshold energy for triggering the switch is 0.4 mJ corresponding to a peak power density ofmore » 27.9 MW/cm{sup 2}. The triggering lifetime of a spot can reach up to 18 000 shots. In addition, the relationship between triggering lifetime and target materials is analyzed using a field emission scanning electron microscope. A hypothesis of the vacuum gap’s triggering mechanism is discussed based on the measured results.« less

  5. Resident-to-resident violence triggers in nursing homes.

    PubMed

    Snellgrove, Susan; Beck, Cornelia; Green, Angela; McSweeney, Jean C

    2013-11-01

    Certified nurses' assistants (CNAs) employed by a rural nursing home in Northeast Arkansas described their perceptions of resident-to-resident violence in order to provide insight on factors, including unmet needs, that may trigger the phenomenon. Semistructured interviews were conducted with 11 CNAs. Data were analyzed using content analysis and constant comparison. Two categories of triggers emerged from the data-active and passive. Active triggers involved the actions of other residents that were intrusive in nature, such as wandering into a residents' personal space, taking a resident's belongings, and so forth. Passive triggers did not involve the actions of residents but related to the internal and external environment of the residents. Examples were factors such as boredom, competition for attention and communication difficulties. Results indicate that there are factors, including unmet needs within the nursing home environment that may be identified and altered to prevent violence between residents.

  6. Creation and Implementation of an Environmental Scan to Assess Cancer Genetics Services at Three Oncology Care Settings.

    PubMed

    Bednar, Erica M; Walsh, Michael T; Baker, Ellen; Muse, Kimberly I; Oakley, Holly D; Krukenberg, Rebekah C; Dresbold, Cara S; Jenkinson, Sandra B; Eppolito, Amanda L; Teed, Kelly B; Klein, Molly H; Morman, Nichole A; Bowdish, Elizabeth C; Russ, Pauline; Wise, Emaline E; Cooper, Julia N; Method, Michael W; Henson, John W; Grainger, Andrew V; Arun, Banu K; Lu, Karen H

    2018-05-16

    An environmental scan (ES) is an efficient mixed-methods approach to collect and interpret relevant data for strategic planning and project design. To date, the ES has not been used nor evaluated in the clinical cancer genetics setting. We created and implemented an ES to inform the design of a quality improvement (QI) project to increase the rates of adherence to national guidelines for cancer genetic counseling and genetic testing at three unique oncology care settings (OCS). The ES collected qualitative and quantitative data from reviews of internal processes, past QI efforts, the literature, and each OCS. The ES used a data collection form and semi-structured interviews to aid in data collection. The ES was completed within 6 months, and sufficient data were captured to identify opportunities and threats to the QI project's success, as well as potential barriers to, and facilitators of guideline-based cancer genetics services at each OCS. Previously unreported barriers were identified, including inefficient genetic counseling appointment scheduling processes and the inability to track referrals, genetics appointments, and genetic test results within electronic medical record systems. The ES was a valuable process for QI project planning at three OCS and may be used to evaluate genetics services in other settings.

  7. More About The Video Event Trigger

    NASA Technical Reports Server (NTRS)

    Williams, Glenn L.

    1996-01-01

    Report presents additional information about system described in "Video Event Trigger" (LEW-15076). Digital electronic system processes video-image data to generate trigger signal when image shows significant change, such as motion, or appearance, disappearance, change in color, brightness, or dilation of object. Potential uses include monitoring of hallways, parking lots, and other areas during hours when supposed unoccupied, looking for fires, tracking airplanes or other moving objects, identification of missing or defective parts on production lines, and video recording of automobile crash tests.

  8. The digital trigger system for the RED-100 detector

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Naumov, P. P., E-mail: ddr727@yandex.ru; Akimov, D. Yu.; Belov, V. A.

    The system for forming a trigger for the liquid xenon detector RED-100 is developed. The trigger can be generated for all types of events that the detector needs for calibration and data acquisition, including the events with a single electron of ionization. In the system, a mechanism of event detection is implemented according to which the timestamp and event type are assigned to each event. The trigger system is required in the systems searching for rare events to select and keep only the necessary information from the ADC array. The specifications and implementation of the trigger unit which provides amore » high efficiency of response even to low-energy events are considered.« less

  9. Filtering large-scale event collections using a combination of supervised and unsupervised learning for event trigger classification.

    PubMed

    Mehryary, Farrokh; Kaewphan, Suwisa; Hakala, Kai; Ginter, Filip

    2016-01-01

    Biomedical event extraction is one of the key tasks in biomedical text mining, supporting various applications such as database curation and hypothesis generation. Several systems, some of which have been applied at a large scale, have been introduced to solve this task. Past studies have shown that the identification of the phrases describing biological processes, also known as trigger detection, is a crucial part of event extraction, and notable overall performance gains can be obtained by solely focusing on this sub-task. In this paper we propose a novel approach for filtering falsely identified triggers from large-scale event databases, thus improving the quality of knowledge extraction. Our method relies on state-of-the-art word embeddings, event statistics gathered from the whole biomedical literature, and both supervised and unsupervised machine learning techniques. We focus on EVEX, an event database covering the whole PubMed and PubMed Central Open Access literature containing more than 40 million extracted events. The top most frequent EVEX trigger words are hierarchically clustered, and the resulting cluster tree is pruned to identify words that can never act as triggers regardless of their context. For rarely occurring trigger words we introduce a supervised approach trained on the combination of trigger word classification produced by the unsupervised clustering method and manual annotation. The method is evaluated on the official test set of BioNLP Shared Task on Event Extraction. The evaluation shows that the method can be used to improve the performance of the state-of-the-art event extraction systems. This successful effort also translates into removing 1,338,075 of potentially incorrect events from EVEX, thus greatly improving the quality of the data. The method is not solely bound to the EVEX resource and can be thus used to improve the quality of any event extraction system or database. The data and source code for this work are available at

  10. An Overview of Recent Advances in Event-Triggered Consensus of Multiagent Systems.

    PubMed

    Ding, Lei; Han, Qing-Long; Ge, Xiaohua; Zhang, Xian-Ming

    2018-04-01

    Event-triggered consensus of multiagent systems (MASs) has attracted tremendous attention from both theoretical and practical perspectives due to the fact that it enables all agents eventually to reach an agreement upon a common quantity of interest while significantly alleviating utilization of communication and computation resources. This paper aims to provide an overview of recent advances in event-triggered consensus of MASs. First, a basic framework of multiagent event-triggered operational mechanisms is established. Second, representative results and methodologies reported in the literature are reviewed and some in-depth analysis is made on several event-triggered schemes, including event-based sampling schemes, model-based event-triggered schemes, sampled-data-based event-triggered schemes, and self-triggered sampling schemes. Third, two examples are outlined to show applicability of event-triggered consensus in power sharing of microgrids and formation control of multirobot systems, respectively. Finally, some challenging issues on event-triggered consensus are proposed for future research.

  11. A neural network z-vertex trigger for Belle II

    NASA Astrophysics Data System (ADS)

    Neuhaus, S.; Skambraks, S.; Abudinen, F.; Chen, Y.; Feindt, M.; Frühwirth, R.; Heck, M.; Kiesling, C.; Knoll, A.; Paul, S.; Schieck, J.

    2015-05-01

    We present the concept of a track trigger for the Belle II experiment, based on a neural network approach, that is able to reconstruct the z (longitudinal) position of the event vertex within the latency of the first level trigger. The trigger will thus be able to suppress a large fraction of the dominating background from events outside of the interaction region. The trigger uses the drift time information of the hits from the Central Drift Chamber (CDC) of Belle II within narrow cones in polar and azimuthal angle as well as in transverse momentum (sectors), and estimates the z-vertex without explicit track reconstruction. The preprocessing for the track trigger is based on the track information provided by the standard CDC trigger. It takes input from the 2D (r — φ) track finder, adds information from the stereo wires of the CDC, and finds the appropriate sectors in the CDC for each track in a given event. Within each sector, the z-vertex of the associated track is estimated by a specialized neural network, with a continuous output corresponding to the scaled z-vertex. The input values for the neural network are calculated from the wire hits of the CDC.

  12. Type 1 diabetes epidemic in Finland is triggered by zinc-containing amorphous silica nanoparticles.

    PubMed

    Junnila, S K

    2015-04-01

    Type 1 diabetes (T1D), an autoimmune disease, breaks out in some of the children who has genetic susceptibility to T1D. Besides genetic susceptibility some environmental factor(s) are required to trigger the disease. The incidence of T1D in Finland is highest in the world, so we must seek an environmental factor, that is typical for Finland and can declare many aspects of T1D epidemiology and biology. In the literature most popular trigger has been enterovirus infections. It is difficult however to find why enteroviruses would be in this role in Finland in contrary to neighbouring countries e.g. Sweden. Colloidal amorphous silica (ASi) is typical for Finnish environment in consequency of the geohistory of Finland, great part of Finland is an ancient lake and sea bottom. ASi concentrations in natural waters are high in April-June and in November, only traces can be found in the rest of months. Pure colloidal ASi is not a strong trigger for T1D, but ASi particle which has surface adsorbed tetrahedrally coordinated zinc (ASiZn) is probably the trigger which has kept it's secret up to date. Zn functions as address label which conducts the ASiZn particle to the beta cell, whose content of zinc is highest in the body. ASi particle adheres to membrane proteins distorting their tertiary structure revealing new epitopes. If the fetus has not met these epitopes at proper time during intrauterine development, the consequence is that the negative selection of lymphocytes in the thymus and bone marrow and fetal liver is not perfect. When a child later in postnatal life becomes predisposed to ASiZn particles the immune system reacts to these as to nonself proteins. As a consequence the insulin producing beta cells are destroyed. Many observations from diabetes research support the hypothesis, some to mentioned. 1. Three common autoantigens (ZnT8, ICA512/IA-2, GAD65) are membrane proteins whose function zinc regulates. 2. Geographical variation in Finland is convergent with

  13. Performance of the ATLAS trigger system in 2015.

    PubMed

    Aaboud, M; Aad, G; Abbott, B; Abdallah, J; Abdinov, O; Abeloos, B; Aben, R; AbouZeid, O S; Abraham, N L; Abramowicz, H; Abreu, H; Abreu, R; Abulaiti, Y; Acharya, B S; Adachi, S; Adamczyk, L; Adams, D L; Adelman, J; Adomeit, S; Adye, T; Affolder, A A; Agatonovic-Jovin, T; Aguilar-Saavedra, J A; Ahlen, S P; Ahmadov, F; Aielli, G; Akerstedt, H; Åkesson, T P A; Akimov, A V; Alberghi, G L; Albert, J; Albrand, S; Alconada Verzini, M J; Aleksa, M; Aleksandrov, I N; Alexa, C; Alexander, G; Alexopoulos, T; Alhroob, M; Ali, B; Aliev, M; Alimonti, G; Alison, J; Alkire, S P; Allbrooke, B M M; Allen, B W; Allport, P P; Aloisio, A; Alonso, A; Alonso, F; Alpigiani, C; Alshehri, A A; Alstaty, M; Alvarez Gonzalez, B; Álvarez Piqueras, D; Alviggi, M G; Amadio, B T; Amaral Coutinho, Y; Amelung, C; Amidei, D; Amor Dos Santos, S P; Amorim, A; Amoroso, S; Amundsen, G; Anastopoulos, C; Ancu, L S; Andari, N; Andeen, T; Anders, C F; Anders, G; Anders, J K; Anderson, K J; Andreazza, A; Andrei, V; Angelidakis, S; Angelozzi, I; Angerami, A; Anghinolfi, F; Anisenkov, A V; Anjos, N; Annovi, A; Antel, C; Antonelli, M; Antonov, A; Antrim, D J; Anulli, F; Aoki, M; Aperio Bella, L; Arabidze, G; Arai, Y; Araque, J P; Arce, A T H; Arduh, F A; Arguin, J-F; Argyropoulos, S; Arik, M; Armbruster, A J; Armitage, L J; Arnaez, O; Arnold, H; Arratia, M; Arslan, O; Artamonov, A; Artoni, G; Artz, S; Asai, S; Asbah, N; Ashkenazi, A; Åsman, B; Asquith, L; Assamagan, K; Astalos, R; Atkinson, M; Atlay, N B; Augsten, K; Avolio, G; Axen, B; Ayoub, M K; Azuelos, G; Baak, M A; Baas, A E; Baca, M J; Bachacou, H; Bachas, K; Backes, M; Backhaus, M; Bagiacchi, P; Bagnaia, P; Bai, Y; Baines, J T; Bajic, M; Baker, O K; Baldin, E M; Balek, P; Balestri, T; Balli, F; Balunas, W K; Banas, E; Banerjee, Sw; Bannoura, A A E; Barak, L; Barberio, E L; Barberis, D; Barbero, M; Barillari, T; Barisits, M-S; Barklow, T; Barlow, N; Barnes, S L; Barnett, B M; Barnett, R M; Barnovska-Blenessy, Z; Baroncelli, A; Barone, G; Barr, A J; Barranco Navarro, L; Barreiro, F; Barreiro Guimarães da Costa, J; Bartoldus, R; Barton, A E; Bartos, P; Basalaev, A; Bassalat, A; Bates, R L; Batista, S J; Batley, J R; Battaglia, M; Bauce, M; Bauer, F; Bawa, H S; Beacham, J B; Beattie, M D; Beau, T; Beauchemin, P H; Bechtle, P; Beck, H P; Becker, K; Becker, M; Beckingham, M; Becot, C; Beddall, A J; Beddall, A; Bednyakov, V A; Bedognetti, M; Bee, C P; Beemster, L J; Beermann, T A; Begel, M; Behr, J K; Bell, A S; Bella, G; Bellagamba, L; Bellerive, A; Bellomo, M; Belotskiy, K; Beltramello, O; Belyaev, N L; Benary, O; Benchekroun, D; Bender, M; Bendtz, K; Benekos, N; Benhammou, Y; Benhar Noccioli, E; Benitez, J; Benjamin, D P; Bensinger, J R; Bentvelsen, S; Beresford, L; Beretta, M; Berge, D; Bergeaas Kuutmann, E; Berger, N; Beringer, J; Berlendis, S; Bernard, N R; Bernius, C; Bernlochner, F U; Berry, T; Berta, P; Bertella, C; Bertoli, G; Bertolucci, F; Bertram, I A; Bertsche, C; Bertsche, D; Besjes, G J; Bessidskaia Bylund, O; Bessner, M; Besson, N; Betancourt, C; Bethani, A; Bethke, S; Bevan, A J; Bianchi, R M; Bianco, M; Biebel, O; Biedermann, D; Bielski, R; Biesuz, N V; Biglietti, M; Bilbao De Mendizabal, J; Billoud, T R V; Bilokon, H; Bindi, M; Bingul, A; Bini, C; Biondi, S; Bisanz, T; Bjergaard, D M; Black, C W; Black, J E; Black, K M; Blackburn, D; Blair, R E; Blazek, T; Bloch, I; Blocker, C; Blue, A; Blum, W; Blumenschein, U; Blunier, S; Bobbink, G J; Bobrovnikov, V S; Bocchetta, S S; Bocci, A; Bock, C; Boehler, M; Boerner, D; Bogaerts, J A; Bogavac, D; Bogdanchikov, A G; Bohm, C; Boisvert, V; Bokan, P; Bold, T; Boldyrev, A S; Bomben, M; Bona, M; Boonekamp, M; Borisov, A; Borissov, G; Bortfeldt, J; Bortoletto, D; Bortolotto, V; Bos, K; Boscherini, D; Bosman, M; Bossio Sola, J D; Boudreau, J; Bouffard, J; Bouhova-Thacker, E V; Boumediene, D; Bourdarios, C; Boutle, S K; Boveia, A; Boyd, J; Boyko, I R; Bracinik, J; Brandt, A; Brandt, G; Brandt, O; Bratzler, U; Brau, B; Brau, J E; Breaden Madden, W D; Brendlinger, K; Brennan, A J; Brenner, L; Brenner, R; Bressler, S; Bristow, T M; Britton, D; Britzger, D; Brochu, F M; Brock, I; Brock, R; Brooijmans, G; Brooks, T; Brooks, W K; Brosamer, J; Brost, E; Broughton, J H; Bruckman de Renstrom, P A; Bruncko, D; Bruneliere, R; Bruni, A; Bruni, G; Bruni, L S; Brunt, B H; Bruschi, M; Bruscino, N; Bryant, P; Bryngemark, L; Buanes, T; Buat, Q; Buchholz, P; Buckley, A G; Budagov, I A; Buehrer, F; Bugge, M K; Bulekov, O; Bullock, D; Burckhart, H; Burdin, S; Burgard, C D; Burger, A M; Burghgrave, B; Burka, K; Burke, S; Burmeister, I; Burr, J T P; Busato, E; Büscher, D; Büscher, V; Bussey, P; Butler, J M; Buttar, C M; Butterworth, J M; Butti, P; Buttinger, W; Buzatu, A; Buzykaev, A R; Cabrera Urbán, S; Caforio, D; Cairo, V M; Cakir, O; Calace, N; Calafiura, P; Calandri, A; Calderini, G; Calfayan, P; Callea, G; Caloba, L P; Calvente Lopez, S; Calvet, D; Calvet, S; Calvet, T P; Camacho Toro, R; Camarda, S; Camarri, P; Cameron, D; Caminal Armadans, R; Camincher, C; Campana, S; Campanelli, M; Camplani, A; Campoverde, A; Canale, V; Canepa, A; Cano Bret, M; Cantero, J; Cao, T; Capeans Garrido, M D M; Caprini, I; Caprini, M; Capua, M; Carbone, R M; Cardarelli, R; Cardillo, F; Carli, I; Carli, T; Carlino, G; Carlson, B T; Carminati, L; Carney, R M D; Caron, S; Carquin, E; Carrillo-Montoya, G D; Carter, J R; Carvalho, J; Casadei, D; Casado, M P; Casolino, M; Casper, D W; Castaneda-Miranda, E; Castelijn, R; Castelli, A; Castillo Gimenez, V; Castro, N F; Catinaccio, A; Catmore, J R; Cattai, A; Caudron, J; Cavaliere, V; Cavallaro, E; Cavalli, D; Cavalli-Sforza, M; Cavasinni, V; Ceradini, F; Cerda Alberich, L; Cerqueira, A S; Cerri, A; Cerrito, L; Cerutti, F; Cervelli, A; Cetin, S A; Chafaq, A; Chakraborty, D; Chan, S K; Chan, Y L; Chang, P; Chapman, J D; Charlton, D G; Chatterjee, A; Chau, C C; Chavez Barajas, C A; Che, S; Cheatham, S; Chegwidden, A; Chekanov, S; Chekulaev, S V; Chelkov, G A; Chelstowska, M A; Chen, C; Chen, H; Chen, K; Chen, S; Chen, S; Chen, X; Chen, Y; Cheng, H C; Cheng, H J; Cheng, Y; Cheplakov, A; Cheremushkina, E; Cherkaoui El Moursli, R; Chernyatin, V; Cheu, E; Chevalier, L; Chiarella, V; Chiarelli, G; Chiodini, G; Chisholm, A S; Chitan, A; Chizhov, M V; Choi, K; Chomont, A R; Chouridou, S; Chow, B K B; Christodoulou, V; Chromek-Burckhart, D; Chudoba, J; Chuinard, A J; Chwastowski, J J; Chytka, L; Ciapetti, G; Ciftci, A K; Cinca, D; Cindro, V; Cioara, I A; Ciocca, C; Ciocio, A; Cirotto, F; Citron, Z H; Citterio, M; Ciubancan, M; Clark, A; Clark, B L; Clark, M R; Clark, P J; Clarke, R N; Clement, C; Coadou, Y; Cobal, M; Coccaro, A; Cochran, J; Colasurdo, L; Cole, B; Colijn, A P; Collot, J; Colombo, T; Compostella, G; Conde Muiño, P; Coniavitis, E; Connell, S H; Connelly, I A; Consorti, V; Constantinescu, S; Conti, G; Conventi, F; Cooke, M; Cooper, B D; Cooper-Sarkar, A M; Cormier, F; Cormier, K J R; Cornelissen, T; Corradi, M; Corriveau, F; Cortes-Gonzalez, A; Cortiana, G; Costa, G; Costa, M J; Costanzo, D; Cottin, G; Cowan, G; Cox, B E; Cranmer, K; Crawley, S J; Cree, G; Crépé-Renaudin, S; Crescioli, F; Cribbs, W A; Crispin Ortuzar, M; Cristinziani, M; Croft, V; Crosetti, G; Cueto, A; Cuhadar Donszelmann, T; Cummings, J; Curatolo, M; Cúth, J; Czirr, H; Czodrowski, P; D'amen, G; D'Auria, S; D'Onofrio, M; Da Cunha Sargedas De Sousa, M J; Da Via, C; Dabrowski, W; Dado, T; Dai, T; Dale, O; Dallaire, F; Dallapiccola, C; Dam, M; Dandoy, J R; Dang, N P; Daniells, A C; Dann, N S; Danninger, M; Dano Hoffmann, M; Dao, V; Darbo, G; Darmora, S; Dassoulas, J; Dattagupta, A; Davey, W; David, C; Davidek, T; Davies, M; Davison, P; Dawe, E; Dawson, I; De, K; de Asmundis, R; De Benedetti, A; De Castro, S; De Cecco, S; De Groot, N; de Jong, P; De la Torre, H; De Lorenzi, F; De Maria, A; De Pedis, D; De Salvo, A; De Sanctis, U; De Santo, A; De Vivie De Regie, J B; Dearnaley, W J; Debbe, R; Debenedetti, C; Dedovich, D V; Dehghanian, N; Deigaard, I; Del Gaudio, M; Del Peso, J; Del Prete, T; Delgove, D; Deliot, F; Delitzsch, C M; Dell'Acqua, A; Dell'Asta, L; Dell'Orso, M; Della Pietra, M; Della Volpe, D; Delmastro, M; Delsart, P A; DeMarco, D A; Demers, S; Demichev, M; Demilly, A; Denisov, S P; Denysiuk, D; Derendarz, D; Derkaoui, J E; Derue, F; Dervan, P; Desch, K; Deterre, C; Dette, K; Deviveiros, P O; Dewhurst, A; Dhaliwal, S; Di Ciaccio, A; Di Ciaccio, L; Di Clemente, W K; Di Donato, C; Di Girolamo, A; Di Girolamo, B; Di Micco, B; Di Nardo, R; Di Simone, A; Di Sipio, R; Di Valentino, D; Diaconu, C; Diamond, M; Dias, F A; Diaz, M A; Diehl, E B; Dietrich, J; Díez Cornell, S; Dimitrievska, A; Dingfelder, J; Dita, P; Dita, S; Dittus, F; Djama, F; Djobava, T; Djuvsland, J I; do Vale, M A B; Dobos, D; Dobre, M; Doglioni, C; Dolejsi, J; Dolezal, Z; Donadelli, M; Donati, S; Dondero, P; Donini, J; Dopke, J; Doria, A; Dova, M T; Doyle, A T; Drechsler, E; Dris, M; Du, Y; Duarte-Campderros, J; Duchovni, E; Duckeck, G; Ducu, O A; Duda, D; Dudarev, A; Dudder, A Chr; Duffield, E M; Duflot, L; Dührssen, M; Dumancic, M; Duncan, A K; Dunford, M; Duran Yildiz, H; Düren, M; Durglishvili, A; Duschinger, D; Dutta, B; Dyndal, M; Eckardt, C; Ecker, K M; Edgar, R C; Edwards, N C; Eifert, T; Eigen, G; Einsweiler, K; Ekelof, T; El Kacimi, M; Ellajosyula, V; Ellert, M; Elles, S; Ellinghaus, F; Elliot, A A; Ellis, N; Elmsheuser, J; Elsing, M; Emeliyanov, D; Enari, Y; Endner, O C; Ennis, J S; Erdmann, J; Ereditato, A; Ernis, G; Ernst, J; Ernst, M; Errede, S; Ertel, E; Escalier, M; Esch, H; Escobar, C; Esposito, B; Etienvre, A I; Etzion, E; Evans, H; Ezhilov, A; Ezzi, M; Fabbri, F; Fabbri, L; Facini, G; Fakhrutdinov, R M; Falciano, S; Falla, R J; Faltova, J; Fang, Y; Fanti, M; Farbin, A; Farilla, A; Farina, C; Farina, E M; Farooque, T; Farrell, S; Farrington, S M; Farthouat, P; Fassi, F; Fassnacht, P; Fassouliotis, D; Faucci Giannelli, M; Favareto, A; Fawcett, W J; Fayard, L; Fedin, O L; Fedorko, W; Feigl, S; Feligioni, L; Feng, C; Feng, E J; Feng, H; Fenyuk, A B; Feremenga, L; Fernandez Martinez, P; Fernandez Perez, S; Ferrando, J; Ferrari, A; Ferrari, P; Ferrari, R; Ferreira de Lima, D E; Ferrer, A; Ferrere, D; Ferretti, C; Fiedler, F; Filipčič, A; Filipuzzi, M; Filthaut, F; Fincke-Keeler, M; Finelli, K D; Fiolhais, M C N; Fiorini, L; Fischer, A; Fischer, C; Fischer, J; Fisher, W C; Flaschel, N; Fleck, I; Fleischmann, P; Fletcher, G T; Fletcher, R R M; Flick, T; Flierl, B M; Flores Castillo, L R; Flowerdew, M J; Forcolin, G T; Formica, A; Forti, A; Foster, A G; Fournier, D; Fox, H; Fracchia, S; Francavilla, P; Franchini, M; Francis, D; Franconi, L; Franklin, M; Frate, M; Fraternali, M; Freeborn, D; Fressard-Batraneanu, S M; Friedrich, F; Froidevaux, D; Frost, J A; Fukunaga, C; Fullana Torregrosa, E; Fusayasu, T; Fuster, J; Gabaldon, C; Gabizon, O; Gabrielli, A; Gabrielli, A; Gach, G P; Gadatsch, S; Gagliardi, G; Gagnon, L G; Gagnon, P; Galea, C; Galhardo, B; Gallas, E J; Gallop, B J; Gallus, P; Galster, G; Gan, K K; Ganguly, S; Gao, J; Gao, Y; Gao, Y S; Garay Walls, F M; García, C; García Navarro, J E; Garcia-Sciveres, M; Gardner, R W; Garelli, N; Garonne, V; Gascon Bravo, A; Gasnikova, K; Gatti, C; Gaudiello, A; Gaudio, G; Gauthier, L; Gavrilenko, I L; Gay, C; Gaycken, G; Gazis, E N; Gecse, Z; Gee, C N P; Geich-Gimbel, Ch; Geisen, M; Geisler, M P; Gellerstedt, K; Gemme, C; Genest, M H; Geng, C; Gentile, S; Gentsos, C; George, S; Gerbaudo, D; Gershon, A; Ghasemi, S; Ghneimat, M; Giacobbe, B; Giagu, S; Giannetti, P; Gibson, S M; Gignac, M; Gilchriese, M; Gillam, T P S; Gillberg, D; Gilles, G; Gingrich, D M; Giokaris, N; Giordani, M P; Giorgi, F M; Giraud, P F; Giromini, P; Giugni, D; Giuli, F; Giuliani, C; Giulini, M; Gjelsten, B K; Gkaitatzis, S; Gkialas, I; Gkougkousis, E L; Gladilin, L K; Glasman, C; Glatzer, J; Glaysher, P C F; Glazov, A; Goblirsch-Kolb, M; Godlewski, J; Goldfarb, S; Golling, T; Golubkov, D; Gomes, A; Gonçalo, R; Goncalves Pinto Firmino Da Costa, J; Gonella, G; Gonella, L; Gongadze, A; González de la Hoz, S; Gonzalez-Sevilla, S; Goossens, L; Gorbounov, P A; Gordon, H A; Gorelov, I; Gorini, B; Gorini, E; Gorišek, A; Gornicki, E; Goshaw, A T; Gössling, C; Gostkin, M I; Goudet, C R; Goujdami, D; Goussiou, A G; Govender, N; Gozani, E; Graber, L; Grabowska-Bold, I; Gradin, P O J; Grafström, P; Gramling, J; Gramstad, E; Grancagnolo, S; Gratchev, V; Gravila, P M; Gray, H M; Graziani, E; Greenwood, Z D; Grefe, C; Gregersen, K; Gregor, I M; Grenier, P; Grevtsov, K; Griffiths, J; Grillo, A A; Grimm, K; Grinstein, S; Gris, Ph; Grivaz, J-F; Groh, S; Gross, E; Grosse-Knetter, J; Grossi, G C; Grout, Z J; Guan, L; Guan, W; Guenther, J; Guescini, F; Guest, D; Gueta, O; Gui, B; Guido, E; Guillemin, T; Guindon, S; Gul, U; Gumpert, C; Guo, J; Guo, Y; Gupta, R; Gupta, S; Gustavino, G; Gutierrez, P; Gutierrez Ortiz, N G; Gutschow, C; Guyot, C; Gwenlan, C; Gwilliam, C B; Haas, A; Haber, C; Hadavand, H K; Haddad, N; Hadef, A; Hageböck, S; Hagihara, M; Hajduk, Z; Hakobyan, H; Haleem, M; Haley, J; Halladjian, G; Hallewell, G D; Hamacher, K; Hamal, P; Hamano, K; Hamilton, A; Hamity, G N; Hamnett, P G; Han, L; Hanagaki, K; Hanawa, K; Hance, M; Haney, B; Hanke, P; Hanna, R; Hansen, J B; Hansen, J D; Hansen, M C; Hansen, P H; Hara, K; Hard, A S; Harenberg, T; Hariri, F; Harkusha, S; Harrington, R D; Harrison, P F; Hartjes, F; Hartmann, N M; Hasegawa, M; Hasegawa, Y; Hasib, A; Hassani, S; Haug, S; Hauser, R; Hauswald, L; Havranek, M; Hawkes, C M; Hawkings, R J; Hayakawa, D; Hayden, D; Hays, C P; Hays, J M; Hayward, H S; Haywood, S J; Head, S J; Heck, T; Hedberg, V; Heelan, L; Heim, S; Heim, T; Heinemann, B; Heinrich, J J; Heinrich, L; Heinz, C; Hejbal, J; Helary, L; Hellman, S; Helsens, C; Henderson, J; Henderson, R C W; Heng, Y; Henkelmann, S; Henriques Correia, A M; Henrot-Versille, S; Herbert, G H; Herde, H; Herget, V; Hernández Jiménez, Y; Herten, G; Hertenberger, R; Hervas, L; Hesketh, G G; Hessey, N P; Hetherly, J W; Higón-Rodriguez, E; Hill, E; Hill, J C; Hiller, K H; Hillier, S J; Hinchliffe, I; Hines, E; Hirose, M; Hirschbuehl, D; Hoad, X; Hobbs, J; Hod, N; Hodgkinson, M C; Hodgson, P; Hoecker, A; Hoeferkamp, M R; Hoenig, F; Hohn, D; Holmes, T R; Homann, M; Honda, T; Hong, T M; Hooberman, B H; Hopkins, W H; Horii, Y; Horton, A J; Hostachy, J-Y; Hou, S; Hoummada, A; Howarth, J; Hoya, J; Hrabovsky, M; Hristova, I; Hrivnac, J; Hryn'ova, T; Hrynevich, A; Hsu, P J; Hsu, S-C; Hu, Q; Hu, S; Huang, Y; Hubacek, Z; Hubaut, F; Huegging, F; Huffman, T B; Hughes, E W; Hughes, G; Huhtinen, M; Huo, P; Huseynov, N; Huston, J; Huth, J; Iacobucci, G; Iakovidis, G; Ibragimov, I; Iconomidou-Fayard, L; Ideal, E; Idrissi, Z; Iengo, P; Igonkina, O; Iizawa, T; Ikai, T; Ikegami, Y; Ikeno, M; Ilchenko, Y; Iliadis, D; Ilic, N; Introzzi, G; Ioannou, P; Iodice, M; Iordanidou, K; Ippolito, V; Ishijima, N; Ishino, M; Ishitsuka, M; Ishmukhametov, R; Issever, C; Istin, S; Ito, F; Iturbe Ponce, J M; Iuppa, R; Iwanski, W; Iwasaki, H; Izen, J M; Izzo, V; Jabbar, S; Jackson, B; Jackson, P; Jain, V; Jakobi, K B; Jakobs, K; Jakobsen, S; Jakoubek, T; Jamin, D O; Jana, D K; Jansky, R; Janssen, J; Janus, M; Janus, P A; Jarlskog, G; Javadov, N; Javůrek, T; Jeanneau, F; Jeanty, L; Jejelava, J; Jeng, G-Y; Jennens, D; Jenni, P; Jeske, C; Jézéquel, S; Ji, H; Jia, J; Jiang, H; Jiang, Y; Jiang, Z; Jiggins, S; Jimenez Pena, J; Jin, S; Jinaru, A; Jinnouchi, O; Jivan, H; Johansson, P; Johns, K A; Johnson, W J; Jon-And, K; Jones, G; Jones, R W L; Jones, S; Jones, T J; Jongmanns, J; Jorge, P M; Jovicevic, J; Ju, X; Juste Rozas, A; Köhler, M K; Kaczmarska, A; Kado, M; Kagan, H; Kagan, M; Kahn, S J; Kaji, T; Kajomovitz, E; Kalderon, C W; Kaluza, A; Kama, S; Kamenshchikov, A; Kanaya, N; Kaneti, S; Kanjir, L; Kantserov, V A; Kanzaki, J; Kaplan, B; Kaplan, L S; Kapliy, A; Kar, D; Karakostas, K; Karamaoun, A; Karastathis, N; Kareem, M J; Karentzos, E; Karnevskiy, M; Karpov, S N; Karpova, Z M; Karthik, K; Kartvelishvili, V; Karyukhin, A N; Kasahara, K; Kashif, L; Kass, R D; Kastanas, A; Kataoka, Y; Kato, C; Katre, A; Katzy, J; Kawade, K; Kawagoe, K; Kawamoto, T; Kawamura, G; Kazanin, V F; Keeler, R; Kehoe, R; Keller, J S; Kempster, J J; Keoshkerian, H; Kepka, O; Kerševan, B P; Kersten, S; Keyes, R A; Khader, M; Khalil-Zada, F; Khanov, A; Kharlamov, A G; Kharlamova, T; Khoo, T J; Khovanskiy, V; Khramov, E; Khubua, J; Kido, S; Kilby, C R; Kim, H Y; Kim, S H; Kim, Y K; Kimura, N; Kind, O M; King, B T; King, M; Kirk, J; Kiryunin, A E; Kishimoto, T; Kisielewska, D; Kiss, F; Kiuchi, K; Kivernyk, O; Kladiva, E; Klein, M H; Klein, M; Klein, U; Kleinknecht, K; Klimek, P; Klimentov, A; Klingenberg, R; Klioutchnikova, T; Kluge, E-E; Kluit, P; Kluth, S; Knapik, J; Kneringer, E; Knoops, E B F G; Knue, A; Kobayashi, A; Kobayashi, D; Kobayashi, T; Kobel, M; Kocian, M; Kodys, P; Koffas, T; Koffeman, E; Köhler, N M; Koi, T; Kolanoski, H; Kolb, M; Koletsou, I; Komar, A A; Komori, Y; Kondo, T; Kondrashova, N; Köneke, K; König, A C; Kono, T; Konoplich, R; Konstantinidis, N; Kopeliansky, R; Koperny, S; Köpke, L; Kopp, A K; Korcyl, K; Kordas, K; Korn, A; Korol, A A; Korolkov, I; Korolkova, E V; Kortner, O; Kortner, S; Kosek, T; Kostyukhin, V V; Kotwal, A; Koulouris, A; Kourkoumeli-Charalampidi, A; Kourkoumelis, C; Kouskoura, V; Kowalewska, A B; Kowalewski, R; Kowalski, T Z; Kozakai, C; Kozanecki, W; Kozhin, A S; Kramarenko, V A; Kramberger, G; Krasnopevtsev, D; Krasny, M W; Krasznahorkay, A; Kravchenko, A; Kretz, M; Kretzschmar, J; Kreutzfeldt, K; Krieger, P; Krizka, K; Kroeninger, K; Kroha, H; Kroll, J; Kroseberg, J; Krstic, J; Kruchonak, U; Krüger, H; Krumnack, N; Kruse, M C; Kruskal, M; Kubota, T; Kucuk, H; Kuday, S; Kuechler, J T; Kuehn, S; Kugel, A; Kuger, F; Kuhl, T; Kukhtin, V; Kukla, R; Kulchitsky, Y; Kuleshov, S; Kuna, M; Kunigo, T; Kupco, A; Kurashige, H; Kurchaninov, L L; Kurochkin, Y A; Kurth, M G; Kus, V; Kuwertz, E S; Kuze, M; Kvita, J; Kwan, T; Kyriazopoulos, D; La Rosa, A; La Rosa Navarro, J L; Rotonda, L La; Lacasta, C; Lacava, F; Lacey, J; Lacker, H; Lacour, D; Lacuesta, V R; Ladygin, E; Lafaye, R; Laforge, B; Lagouri, T; Lai, S; Lammers, S; Lampl, W; Lançon, E; Landgraf, U; Landon, M P J; Lanfermann, M C; Lang, V S; Lange, J C; Lankford, A J; Lanni, F; Lantzsch, K; Lanza, A; Laplace, S; Lapoire, C; Laporte, J F; Lari, T; Lasagni Manghi, F; Lassnig, M; Laurelli, P; Lavrijsen, W; Law, A T; Laycock, P; Lazovich, T; Lazzaroni, M; Le, B; Le Dortz, O; Le Guirriec, E; Le Quilleuc, E P; LeBlanc, M; LeCompte, T; Ledroit-Guillon, F; Lee, C A; Lee, S C; Lee, L; Lefebvre, B; Lefebvre, G; Lefebvre, M; Legger, F; Leggett, C; Lehan, A; Lehmann Miotto, G; Lei, X; Leight, W A; Leister, A G; Leite, M A L; Leitner, R; Lellouch, D; Lemmer, B; Leney, K J C; Lenz, T; Lenzi, B; Leone, R; Leone, S; Leonidopoulos, C; Leontsinis, S; Lerner, G; Leroy, C; Lesage, A A J; Lester, C G; Levchenko, M; Levêque, J; Levin, D; Levinson, L J; Levy, M; Lewis, D; Leyton, M; Li, B; Li, C; Li, H; Li, L; Li, L; Li, Q; Li, S; Li, X; Li, Y; Liang, Z; Liberti, B; Liblong, A; Lichard, P; Lie, K; Liebal, J; Liebig, W; Limosani, A; Lin, S C; Lin, T H; Lindquist, B E; Lionti, A E; Lipeles, E; Lipniacka, A; Lisovyi, M; Liss, T M; Lister, A; Litke, A M; Liu, B; Liu, D; Liu, H; Liu, H; Liu, J; Liu, J B; Liu, K; Liu, L; Liu, M; Liu, Y L; Liu, Y; Livan, M; Lleres, A; Llorente Merino, J; Lloyd, S L; Lo Sterzo, F; Lobodzinska, E M; Loch, P; Loebinger, F K; Loew, K M; Loginov, A; Lohse, T; Lohwasser, K; Lokajicek, M; Long, B A; Long, J D; Long, R E; Longo, L; Looper, K A; Lopez Lopez, J A; Lopez Mateos, D; Lopez Paredes, B; Lopez Paz, I; Lopez Solis, A; Lorenz, J; Lorenzo Martinez, N; Losada, M; Lösel, P J; Lou, X; Lounis, A; Love, J; Love, P A; Lu, H; Lu, N; Lubatti, H J; Luci, C; Lucotte, A; Luedtke, C; Luehring, F; Lukas, W; Luminari, L; Lundberg, O; Lund-Jensen, B; Luzi, P M; Lynn, D; Lysak, R; Lytken, E; Lyubushkin, V; Ma, H; Ma, L L; Ma, Y; Maccarrone, G; Macchiolo, A; Macdonald, C M; Maček, B; Machado Miguens, J; Madaffari, D; Madar, R; Maddocks, H J; Mader, W F; Madsen, A; Maeda, J; Maeland, S; Maeno, T; Maevskiy, A; Magradze, E; Mahlstedt, J; Maiani, C; Maidantchik, C; Maier, A A; Maier, T; Maio, A; Majewski, S; Makida, Y; Makovec, N; Malaescu, B; Malecki, Pa; Maleev, V P; Malek, F; Mallik, U; Malon, D; Malone, C; Malone, C; Maltezos, S; Malyukov, S; Mamuzic, J; Mancini, G; Mandelli, L; Mandić, I; Maneira, J; Manhaes de Andrade Filho, L; Manjarres Ramos, J; Mann, A; Manousos, A; Mansoulie, B; Mansour, J D; Mantifel, R; Mantoani, M; Manzoni, S; Mapelli, L; Marceca, G; March, L; Marchiori, G; Marcisovsky, M; Marjanovic, M; Marley, D E; Marroquim, F; Marsden, S P; Marshall, Z; Marti-Garcia, S; Martin, B; Martin, T A; Martin, V J; Martin Dit Latour, B; Martinez, M; Martinez Outschoorn, V I; Martin-Haugh, S; Martoiu, V S; Martyniuk, A C; Marzin, A; Masetti, L; Mashimo, T; Mashinistov, R; Masik, J; Maslennikov, A L; Massa, I; Massa, L; Mastrandrea, P; Mastroberardino, A; Masubuchi, T; Mättig, P; Mattmann, J; Maurer, J; Maxfield, S J; Maximov, D A; Mazini, R; Maznas, I; Mazza, S M; Mc Fadden, N C; Mc Goldrick, G; Mc Kee, S P; McCarn, A; McCarthy, R L; McCarthy, T G; McClymont, L I; McDonald, E F; Mcfayden, J A; Mchedlidze, G; McMahon, S J; McNamara, P C; McPherson, R A; Medinnis, M; Meehan, S; Mehlhase, S; Mehta, A; Meier, K; Meineck, C; Meirose, B; Melini, D; Mellado Garcia, B R; Melo, M; Meloni, F; Menary, S B; Meng, L; Meng, X T; Mengarelli, A; Menke, S; Meoni, E; Mergelmeyer, S; Mermod, P; Merola, L; Meroni, C; Merritt, F S; Messina, A; Metcalfe, J; Mete, A S; Meyer, C; Meyer, C; Meyer, J-P; Meyer, J; Meyer Zu Theenhausen, H; Miano, F; Middleton, R P; Miglioranzi, S; Mijović, L; Mikenberg, G; Mikestikova, M; Mikuž, M; Milesi, M; Milic, A; Miller, D W; Mills, C; Milov, A; Milstead, D A; Minaenko, A A; Minami, Y; Minashvili, I A; Mincer, A I; Mindur, B; Mineev, M; Minegishi, Y; Ming, Y; Mir, L M; Mistry, K P; Mitani, T; Mitrevski, J; Mitsou, V A; Miucci, A; Miyagawa, P S; Mizukami, A; Mjörnmark, J U; Mlynarikova, M; Moa, T; Mochizuki, K; Mogg, P; Mohapatra, S; Molander, S; Moles-Valls, R; Monden, R; Mondragon, M C; Mönig, K; Monk, J; Monnier, E; Montalbano, A; Montejo Berlingen, J; Monticelli, F; Monzani, S; Moore, R W; Morange, N; Moreno, D; Moreno Llácer, M; Morettini, P; Morgenstern, S; Mori, D; Mori, T; Morii, M; Morinaga, M; Morisbak, V; Moritz, S; Morley, A K; Mornacchi, G; Morris, J D; Mortensen, S S; Morvaj, L; Moschovakos, P; Mosidze, M; Moss, H J; Moss, J; Motohashi, K; Mount, R; Mountricha, E; Moyse, E J W; Muanza, S; Mudd, R D; Mueller, F; Mueller, J; Mueller, R S P; Mueller, T; Muenstermann, D; Mullen, P; Mullier, G A; Munoz Sanchez, F J; Murillo Quijada, J A; Murray, W J; Musheghyan, H; Muškinja, M; Myagkov, A G; Myska, M; Nachman, B P; Nackenhorst, O; Nagai, K; Nagai, R; Nagano, K; Nagasaka, Y; Nagata, K; Nagel, M; Nagy, E; Nairz, A M; Nakahama, Y; Nakamura, K; Nakamura, T; Nakano, I; Naranjo Garcia, R F; Narayan, R; Narrias Villar, D I; Naryshkin, I; Naumann, T; Navarro, G; Nayyar, R; Neal, H A; Nechaeva, P Yu; Neep, T J; Negri, A; Negrini, M; Nektarijevic, S; Nellist, C; Nelson, A; Nemecek, S; Nemethy, P; Nepomuceno, A A; Nessi, M; Neubauer, M S; Neumann, M; Neves, R M; Nevski, P; Newman, P R; Nguyen, D H; Nguyen Manh, T; Nickerson, R B; Nicolaidou, R; Nielsen, J; Nikiforov, A; Nikolaenko, V; Nikolic-Audit, I; Nikolopoulos, K; Nilsen, J K; Nilsson, P; Ninomiya, Y; Nisati, A; Nisius, R; Nobe, T; Nomachi, M; Nomidis, I; Nooney, T; Norberg, S; Nordberg, M; Norjoharuddeen, N; Novgorodova, O; Nowak, S; Nozaki, M; Nozka, L; Ntekas, K; Nurse, E; Nuti, F; O'grady, F; O'Neil, D C; O'Rourke, A A; O'Shea, V; Oakham, F G; Oberlack, H; Obermann, T; Ocariz, J; Ochi, A; Ochoa, I; Ochoa-Ricoux, J P; Oda, S; Odaka, S; Ogren, H; Oh, A; Oh, S H; Ohm, C C; Ohman, H; Oide, H; Okawa, H; Okumura, Y; Okuyama, T; Olariu, A; Oleiro Seabra, L F; Olivares Pino, S A; Damazio, D Oliveira; Olszewski, A; Olszowska, J; Onofre, A; Onogi, K; Onyisi, P U E; Oreglia, M J; Oren, Y; Orestano, D; Orlando, N; Orr, R S; Osculati, B; Ospanov, R; Otero Y Garzon, G; Otono, H; Ouchrif, M; Ould-Saada, F; Ouraou, A; Oussoren, K P; Ouyang, Q; Owen, M; Owen, R E; Ozcan, V E; Ozturk, N; Pachal, K; Pacheco Pages, A; Pacheco Rodriguez, L; Padilla Aranda, C; Pagáčová, M; Pagan Griso, S; Paganini, M; Paige, F; Pais, P; Pajchel, K; Palacino, G; Palazzo, S; Palestini, S; Palka, M; Pallin, D; St Panagiotopoulou, E; Panagoulias, I; Pandini, C E; Panduro Vazquez, J G; Pani, P; Panitkin, S; Pantea, D; Paolozzi, L; Papadopoulou, Th D; Papageorgiou, K; Paramonov, A; Paredes Hernandez, D; Parker, A J; Parker, M A; Parker, K A; Parodi, F; Parsons, J A; Parzefall, U; Pascuzzi, V R; Pasqualucci, E; Passaggio, S; Pastore, Fr; Pásztor, G; Pataraia, S; Pater, J R; Pauly, T; Pearce, J; Pearson, B; Pedersen, L E; Pedersen, M; Pedraza Lopez, S; Pedro, R; Peleganchuk, S V; Penc, O; Peng, C; Peng, H; Penwell, J; Peralva, B S; Perego, M M; Perepelitsa, D V; Perez Codina, E; Perini, L; Pernegger, H; Perrella, S; Peschke, R; Peshekhonov, V D; Peters, K; Peters, R F Y; Petersen, B A; Petersen, T C; Petit, E; Petridis, A; Petridou, C; Petroff, P; Petrolo, E; Petrov, M; Petrucci, F; Pettersson, N E; Peyaud, A; Pezoa, R; Phillips, P W; Piacquadio, G; Pianori, E; Picazio, A; Piccaro, E; Piccinini, M; Pickering, M A; Piegaia, R; Pilcher, J E; Pilkington, A D; Pin, A W J; Pinamonti, M; Pinfold, J L; Pingel, A; Pires, S; Pirumov, H; Pitt, M; Plazak, L; Pleier, M-A; Pleskot, V; Plotnikova, E; Pluth, D; Poettgen, R; Poggioli, L; Pohl, D; Polesello, G; Poley, A; Policicchio, A; Polifka, R; Polini, A; Pollard, C S; Polychronakos, V; Pommès, K; Pontecorvo, L; Pope, B G; Popeneciu, G A; Poppleton, A; Pospisil, S; Potamianos, K; Potrap, I N; Potter, C J; Potter, C T; Poulard, G; Poveda, J; Pozdnyakov, V; Pozo Astigarraga, M E; Pralavorio, P; Pranko, A; Prell, S; Price, D; Price, L E; Primavera, M; Prince, S; Prokofiev, K; Prokoshin, F; Protopopescu, S; Proudfoot, J; Przybycien, M; Puddu, D; Purohit, M; Puzo, P; Qian, J; Qin, G; Qin, Y; Quadt, A; Quayle, W B; Queitsch-Maitland, M; Quilty, D; Raddum, S; Radeka, V; Radescu, V; Radhakrishnan, S K; Radloff, P; Rados, P; Ragusa, F; Rahal, G; Raine, J A; Rajagopalan, S; Rammensee, M; Rangel-Smith, C; Ratti, M G; Rauch, D M; Rauscher, F; Rave, S; Ravenscroft, T; Ravinovich, I; Raymond, M; Read, A L; Readioff, N P; Reale, M; Rebuzzi, D M; Redelbach, A; Redlinger, G; Reece, R; Reed, R G; Reeves, K; Rehnisch, L; Reichert, J; Reiss, A; Rembser, C; Ren, H; Rescigno, M; Resconi, S; Rezanova, O L; Reznicek, P; Rezvani, R; Richter, R; Richter, S; Richter-Was, E; Ricken, O; Ridel, M; Rieck, P; Riegel, C J; Rieger, J; Rifki, O; Rijssenbeek, M; Rimoldi, A; Rimoldi, M; Rinaldi, L; Ristić, B; Ritsch, E; Riu, I; Rizatdinova, F; Rizvi, E; Rizzi, C; Robertson, S H; Robichaud-Veronneau, A; Robinson, D; Robinson, J E M; Robson, A; Roda, C; Rodina, Y; Rodriguez Perez, A; Rodriguez Rodriguez, D; Roe, S; Rogan, C S; Røhne, O; Roloff, J; Romaniouk, A; Romano, M; Romano Saez, S M; Romero Adam, E; Rompotis, N; Ronzani, M; Roos, L; Ros, E; Rosati, S; Rosbach, K; Rose, P; Rosien, N-A; Rossetti, V; Rossi, E; Rossi, L P; Rosten, J H N; Rosten, R; Rotaru, M; Roth, I; Rothberg, J; Rousseau, D; Rozanov, A; Rozen, Y; Ruan, X; Rubbo, F; Rudolph, M S; Rühr, F; Ruiz-Martinez, A; Rurikova, Z; Rusakovich, N A; Ruschke, A; Russell, H L; Rutherfoord, J P; Ruthmann, N; Ryabov, Y F; Rybar, M; Rybkin, G; Ryu, S; Ryzhov, A; Rzehorz, G F; Saavedra, A F; Sabato, G; Sacerdoti, S; Sadrozinski, H F-W; Sadykov, R; Safai Tehrani, F; Saha, P; Sahinsoy, M; Saimpert, M; Saito, T; Sakamoto, H; Sakurai, Y; Salamanna, G; Salamon, A; Salazar Loyola, J E; Salek, D; Sales De Bruin, P H; Salihagic, D; Salnikov, A; Salt, J; Salvatore, D; Salvatore, F; Salvucci, A; Salzburger, A; Sammel, D; Sampsonidis, D; Sánchez, J; Sanchez Martinez, V; Sanchez Pineda, A; Sandaker, H; Sandbach, R L; Sandhoff, M; Sandoval, C; Sankey, D P C; Sannino, M; Sansoni, A; Santoni, C; Santonico, R; Santos, H; Santoyo Castillo, I; Sapp, K; Sapronov, A; Saraiva, J G; Sarrazin, B; Sasaki, O; Sato, K; Sauvan, E; Savage, G; Savard, P; Savic, N; Sawyer, C; Sawyer, L; Saxon, J; Sbarra, C; Sbrizzi, A; Scanlon, T; Scannicchio, D A; Scarcella, M; Scarfone, V; Schaarschmidt, J; Schacht, P; Schachtner, B M; Schaefer, D; Schaefer, L; Schaefer, R; Schaeffer, J; Schaepe, S; Schaetzel, S; Schäfer, U; Schaffer, A C; Schaile, D; Schamberger, R D; Scharf, V; Schegelsky, V A; Scheirich, D; Schernau, M; Schiavi, C; Schier, S; Schillo, C; Schioppa, M; Schlenker, S; Schmidt-Sommerfeld, K R; Schmieden, K; Schmitt, C; Schmitt, S; Schmitz, S; Schneider, B; Schnoor, U; Schoeffel, L; Schoening, A; Schoenrock, B D; Schopf, E; Schott, M; Schouwenberg, J F P; Schovancova, J; Schramm, S; Schreyer, M; Schuh, N; Schulte, A; Schultens, M J; Schultz-Coulon, H-C; Schulz, H; Schumacher, M; Schumm, B A; Schune, Ph; Schwartzman, A; Schwarz, T A; Schweiger, H; Schwemling, Ph; Schwienhorst, R; Schwindling, J; Schwindt, T; Sciolla, G; Scuri, F; Scutti, F; Searcy, J; Seema, P; Seidel, S C; Seiden, A; Seifert, F; Seixas, J M; Sekhniaidze, G; Sekhon, K; Sekula, S J; Seliverstov, D M; Semprini-Cesari, N; Serfon, C; Serin, L; Serkin, L; Sessa, M; Seuster, R; Severini, H; Sfiligoj, T; Sforza, F; Sfyrla, A; Shabalina, E; Shaikh, N W; Shan, L Y; Shang, R; Shank, J T; Shapiro, M; Shatalov, P B; Shaw, K; Shaw, S M; Shcherbakova, A; Shehu, C Y; Sherwood, P; Shi, L; Shimizu, S; Shimmin, C O; Shimojima, M; Shirabe, S; Shiyakova, M; Shmeleva, A; Shoaleh Saadi, D; Shochet, M J; Shojaii, S; Shope, D R; Shrestha, S; Shulga, E; Shupe, M A; Sicho, P; Sickles, A M; Sidebo, P E; Sideras Haddad, E; Sidiropoulou, O; Sidorov, D; Sidoti, A; Siegert, F; Sijacki, Dj; Silva, J; Silverstein, S B; Simak, V; Simic, Lj; Simion, S; Simioni, E; Simmons, B; Simon, D; Simon, M; Sinervo, P; Sinev, N B; Sioli, M; Siragusa, G; Sivoklokov, S Yu; Sjölin, J; Skinner, M B; Skottowe, H P; Skubic, P; Slater, M; Slavicek, T; Slawinska, M; Sliwa, K; Slovak, R; Smakhtin, V; Smart, B H; Smestad, L; Smiesko, J; Smirnov, S Yu; Smirnov, Y; Smirnova, L N; Smirnova, O; Smith, J W; Smith, M N K; Smith, R W; Smizanska, M; Smolek, K; Snesarev, A A; Snyder, I M; Snyder, S; Sobie, R; Socher, F; Soffer, A; Soh, D A; Sokhrannyi, G; Solans Sanchez, C A; Solar, M; Soldatov, E Yu; Soldevila, U; Solodkov, A A; Soloshenko, A; Solovyanov, O V; Solovyev, V; Sommer, P; Son, H; Song, H Y; Sood, A; Sopczak, A; Sopko, V; Sorin, V; Sosa, D; Sotiropoulou, C L; Soualah, R; Soukharev, A M; South, D; Sowden, B C; Spagnolo, S; Spalla, M; Spangenberg, M; Spanò, F; Sperlich, D; Spettel, F; Spieker, T M; Spighi, R; Spigo, G; Spiller, L A; Spousta, M; St Denis, R D; Stabile, A; Stamen, R; Stamm, S; Stanecka, E; Stanek, R W; Stanescu, C; Stanescu-Bellu, M; Stanitzki, M M; Stapnes, S; Starchenko, E A; Stark, G H; Stark, J; Staroba, P; Starovoitov, P; Stärz, S; Staszewski, R; Steinberg, P; Stelzer, B; Stelzer, H J; Stelzer-Chilton, O; Stenzel, H; Stewart, G A; Stillings, J A; Stockton, M C; Stoebe, M; Stoicea, G; Stolte, P; Stonjek, S; Stradling, A R; Straessner, A; Stramaglia, M E; Strandberg, J; Strandberg, S; Strandlie, A; Strauss, M; Strizenec, P; Ströhmer, R; Strom, D M; Stroynowski, R; Strubig, A; Stucci, S A; Stugu, B; Styles, N A; Su, D; Su, J; Suchek, S; Sugaya, Y; Suk, M; Sulin, V V; Sultansoy, S; Sumida, T; Sun, S; Sun, X; Sundermann, J E; Suruliz, K; Suster, C J E; Sutton, M R; Suzuki, S; Svatos, M; Swiatlowski, M; Swift, S P; Sykora, I; Sykora, T; Ta, D; Taccini, C; Tackmann, K; Taenzer, J; Taffard, A; Tafirout, R; Taiblum, N; Takai, H; Takashima, R; Takeshita, T; Takubo, Y; Talby, M; Talyshev, A A; Tan, K G; Tanaka, J; Tanaka, M; Tanaka, R; Tanaka, S; Tanioka, R; Tannenwald, B B; Tapia Araya, S; Tapprogge, S; Tarem, S; Tartarelli, G F; Tas, P; Tasevsky, M; Tashiro, T; Tassi, E; Tavares Delgado, A; Tayalati, Y; Taylor, A C; Taylor, G N; Taylor, P T E; Taylor, W; Teischinger, F A; Teixeira-Dias, P; Temming, K K; Temple, D; Ten Kate, H; Teng, P K; Teoh, J J; Tepel, F; Terada, S; Terashi, K; Terron, J; Terzo, S; Testa, M; Teuscher, R J; Theveneaux-Pelzer, T; Thomas, J P; Thomas-Wilsker, J; Thompson, P D; Thompson, A S; Thomsen, L A; Thomson, E; Tibbetts, M J; Ticse Torres, R E; Tikhomirov, V O; Tikhonov, Yu A; Timoshenko, S; Tipton, P; Tisserant, S; Todome, K; Todorov, T; Todorova-Nova, S; Tojo, J; Tokár, S; Tokushuku, K; Tolley, E; Tomlinson, L; Tomoto, M; Tompkins, L; Toms, K; Tong, B; Tornambe, P; Torrence, E; Torres, H; Torró Pastor, E; Toth, J; Touchard, F; Tovey, D R; Trefzger, T; Tricoli, A; Trigger, I M; Trincaz-Duvoid, S; Tripiana, M F; Trischuk, W; Trocmé, B; Trofymov, A; Troncon, C; Trottier-McDonald, M; Trovatelli, M; Truong, L; Trzebinski, M; Trzupek, A; Tseng, J C-L; Tsiareshka, P V; Tsipolitis, G; Tsirintanis, N; Tsiskaridze, S; Tsiskaridze, V; Tskhadadze, E G; Tsui, K M; Tsukerman, I I; Tsulaia, V; Tsuno, S; Tsybychev, D; Tu, Y; Tudorache, A; Tudorache, V; Tulbure, T T; Tuna, A N; Tupputi, S A; Turchikhin, S; Turgeman, D; Turk Cakir, I; Turra, R; Tuts, P M; Ucchielli, G; Ueda, I; Ughetto, M; Ukegawa, F; Unal, G; Undrus, A; Unel, G; Ungaro, F C; Unno, Y; Unverdorben, C; Urban, J; Urquijo, P; Urrejola, P; Usai, G; Usui, J; Vacavant, L; Vacek, V; Vachon, B; Valderanis, C; Valdes Santurio, E; Valencic, N; Valentinetti, S; Valero, A; Valery, L; Valkar, S; Valls Ferrer, J A; Van Den Wollenberg, W; Van Der Deijl, P C; van der Graaf, H; van Eldik, N; van Gemmeren, P; Van Nieuwkoop, J; van Vulpen, I; van Woerden, M C; Vanadia, M; Vandelli, W; Vanguri, R; Vaniachine, A; Vankov, P; Vardanyan, G; Vari, R; Varnes, E W; Varol, T; Varouchas, D; Vartapetian, A; Varvell, K E; Vasquez, J G; Vasquez, G A; Vazeille, F; Vazquez Schroeder, T; Veatch, J; Veeraraghavan, V; Veloce, L M; Veloso, F; Veneziano, S; Ventura, A; Venturi, M; Venturi, N; Venturini, A; Vercesi, V; Verducci, M; Verkerke, W; Vermeulen, J C; Vest, A; Vetterli, M C; Viazlo, O; Vichou, I; Vickey, T; Vickey Boeriu, O E; Viehhauser, G H A; Viel, S; Vigani, L; Villa, M; Villaplana Perez, M; Vilucchi, E; Vincter, M G; Vinogradov, V B; Vittori, C; Vivarelli, I; Vlachos, S; Vlasak, M; Vogel, M; Vokac, P; Volpi, G; Volpi, M; von der Schmitt, H; von Toerne, E; Vorobel, V; Vorobev, K; Vos, M; Voss, R; Vossebeld, J H; Vranjes, N; Vranjes Milosavljevic, M; Vrba, V; Vreeswijk, M; Vuillermet, R; Vukotic, I; Wagner, P; Wagner, W; Wahlberg, H; Wahrmund, S; Wakabayashi, J; Walder, J; Walker, R; Walkowiak, W; Wallangen, V; Wang, C; Wang, C; Wang, F; Wang, H; Wang, H; Wang, J; Wang, J; Wang, K; Wang, R; Wang, S M; Wang, T; Wang, W; Wanotayaroj, C; Warburton, A; Ward, C P; Wardrope, D R; Washbrook, A; Watkins, P M; Watson, A T; Watson, M F; Watts, G; Watts, S; Waugh, B M; Webb, S; Weber, M S; Weber, S W; Weber, S A; Webster, J S; Weidberg, A R; Weinert, B; Weingarten, J; Weiser, C; Weits, H; Wells, P S; Wenaus, T; Wengler, T; Wenig, S; Wermes, N; Werner, M D; Werner, P; Wessels, M; Wetter, J; Whalen, K; Whallon, N L; Wharton, A M; White, A; White, M J; White, R; Whiteson, D; Wickens, F J; Wiedenmann, W; Wielers, M; Wiglesworth, C; Wiik-Fuchs, L A M; Wildauer, A; Wilk, F; Wilkens, H G; Williams, H H; Williams, S; Willis, C; Willocq, S; Wilson, J A; Wingerter-Seez, I; Winklmeier, F; Winston, O J; Winter, B T; Wittgen, M; Wolf, T M H; Wolff, R; Wolter, M W; Wolters, H; Worm, S D; Wosiek, B K; Wotschack, J; Woudstra, M J; Wozniak, K W; Wu, M; Wu, M; Wu, S L; Wu, X; Wu, Y; Wyatt, T R; Wynne, B M; Xella, S; Xi, Z; Xu, D; Xu, L; Yabsley, B; Yacoob, S; Yamaguchi, D; Yamaguchi, Y; Yamamoto, A; Yamamoto, S; Yamanaka, T; Yamauchi, K; Yamazaki, Y; Yan, Z; Yang, H; Yang, H; Yang, Y; Yang, Z; Yao, W-M; Yap, Y C; Yasu, Y; Yatsenko, E; Yau Wong, K H; Ye, J; Ye, S; Yeletskikh, I; Yildirim, E; Yorita, K; Yoshida, R; Yoshihara, K; Young, C; Young, C J S; Youssef, S; Yu, D R; Yu, J; Yu, J M; Yu, J; Yuan, L; Yuen, S P Y; Yusuff, I; Zabinski, B; Zacharis, G; Zaidan, R; Zaitsev, A M; Zakharchuk, N; Zalieckas, J; Zaman, A; Zambito, S; Zanello, L; Zanzi, D; Zeitnitz, C; Zeman, M; Zemla, A; Zeng, J C; Zeng, Q; Zenin, O; Ženiš, T; Zerwas, D; Zhang, D; Zhang, F; Zhang, G; Zhang, H; Zhang, J; Zhang, L; Zhang, L; Zhang, M; Zhang, R; Zhang, R; Zhang, X; Zhang, Z; Zhao, X; Zhao, Y; Zhao, Z; Zhemchugov, A; Zhong, J; Zhou, B; Zhou, C; Zhou, L; Zhou, L; Zhou, M; Zhou, N; Zhu, C G; Zhu, H; Zhu, J; Zhu, Y; Zhuang, X; Zhukov, K; Zibell, A; Zieminska, D; Zimine, N I; Zimmermann, C; Zimmermann, S; Zinonos, Z; Zinser, M; Ziolkowski, M; Živković, L; Zobernig, G; Zoccoli, A; Zur Nedden, M; Zwalinski, L

    2017-01-01

    During 2015 the ATLAS experiment recorded [Formula: see text] of proton-proton collision data at a centre-of-mass energy of [Formula: see text]. The ATLAS trigger system is a crucial component of the experiment, responsible for selecting events of interest at a recording rate of approximately 1 kHz from up to 40 MHz of collisions. This paper presents a short overview of the changes to the trigger and data acquisition systems during the first long shutdown of the LHC and shows the performance of the trigger system and its components based on the 2015 proton-proton collision data.

  14. Performance of the ATLAS trigger system in 2015

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aaboud, M.; Aad, G.; Abbott, B.

    During 2015 the ATLAS experiment recorded 3.8fb –1 of proton–proton collision data at a centre-of-mass energy of 13TeV. The ATLAS trigger system is a crucial component of the experiment, responsible for selecting events of interest at a recording rate of approximately 1 kHz from up to 40 MHz of collisions. This paper presents a short overview of the changes to the trigger and data acquisition systems during the first long shutdown of the LHC and shows the performance of the trigger system and its components based on the 2015 proton–proton collision data.

  15. Performance of the ATLAS trigger system in 2015

    DOE PAGES

    Aaboud, M.; Aad, G.; Abbott, B.; ...

    2017-05-18

    During 2015 the ATLAS experiment recorded 3.8fb –1 of proton–proton collision data at a centre-of-mass energy of 13TeV. The ATLAS trigger system is a crucial component of the experiment, responsible for selecting events of interest at a recording rate of approximately 1 kHz from up to 40 MHz of collisions. This paper presents a short overview of the changes to the trigger and data acquisition systems during the first long shutdown of the LHC and shows the performance of the trigger system and its components based on the 2015 proton–proton collision data.

  16. Environmental site assessments and audits: Building inspection requirements

    NASA Astrophysics Data System (ADS)

    Lange, John H.; Kaiser, Genevieve; Thomulka, Kenneth W.

    1994-01-01

    Environmental site assessment criteria were originally developed by organizations that focused, almost exclusively, on surface, subsurface, and pollution source contamination. Many of the hazards associated with indoor environments and building structures were traditionally not considered when evaluating sources and entities of environmental pollution. Since a large number of building materials are potentially hazardous, careful evaluation is necessary. Until recently, little information on building inspection requirements of environmental problems has been published. Traditionally, asbestos has been the main component of concern. The ever-changing environmental standards have dramatically expanded the scope of building surveys. Indoor environmental concerns, for example, currently include formaldehyde, lead-based paint, polychlorinated biphenyls, radon, and indoor air pollution. Environmental regulations are being expanded and developed that specifically include building structures. These regulatory standards are being triggered by an increased awareness of health effects from indoor exposure, fires, spills, and other accidents that have resulted in injury, death, and financial loss. This article discusses various aspects of assessments for building structures.

  17. Tracking at High Level Trigger in CMS

    NASA Astrophysics Data System (ADS)

    Tosi, M.

    2016-04-01

    The trigger systems of the LHC detectors play a crucial role in determining the physics capabilities of experiments. A reduction of several orders of magnitude of the event rate is needed to reach values compatible with detector readout, offline storage and analysis capability. The CMS experiment has been designed with a two-level trigger system: the Level-1 Trigger (L1T), implemented on custom-designed electronics, and the High Level Trigger (HLT), a streamlined version of the CMS offline reconstruction software running on a computer farm. A software trigger system requires a trade-off between the complexity of the algorithms, the sustainable output rate, and the selection efficiency. With the computing power available during the 2012 data taking the maximum reconstruction time at HLT was about 200 ms per event, at the nominal L1T rate of 100 kHz. Track reconstruction algorithms are widely used in the HLT, for the reconstruction of the physics objects as well as in the identification of b-jets and lepton isolation. Reconstructed tracks are also used to distinguish the primary vertex, which identifies the hard interaction process, from the pileup ones. This task is particularly important in the LHC environment given the large number of interactions per bunch crossing: on average 25 in 2012, and expected to be around 40 in Run II. We will present the performance of HLT tracking algorithms, discussing its impact on CMS physics program, as well as new developments done towards the next data taking in 2015.

  18. Understanding Environmental Tobacco Smoke Exposure and Effects in Asthmatic Children through Determination of Urinary Cotinine and Targeted Metabolomics of Plasma

    EPA Science Inventory

    Understanding Environmental Tobacco Smoke Exposure and Effects in Asthmatic Children through Determination of Urinary Cotinine and Targeted Metabolomics of Plasma Introduction Asthma is a complex disease with multiple triggers and causal factors, Exposure to environmental tob...

  19. Environmental Factors in Autism

    PubMed Central

    Grabrucker, Andreas M.

    2013-01-01

    Autism is a neurodevelopmental disorders characterized by impairments in communication and social behavior, and by repetitive behaviors. Although genetic factors might be largely responsible for the occurrence of autism they cannot fully account for all cases and it is likely that in addition to a certain combination of autism-related genes, specific environmental factors might act as risk factors triggering the development of autism. Thus, the role of environmental factors in autism is an important area of research and recent data will be discussed in this review. Interestingly, the results show that many environmental risk factors are interrelated and their identification and comparison might unveil a common scheme of alterations on a contextual as well as molecular level. For example, both, disruption in the immune system and in zinc homeostasis may affect synaptic transmission in autism. Thus, here, a model is proposed that interconnects the most important and scientifically recognized environmental factors. Moreover, similarities in how these risk factors impact synapse function are discussed and a possible influence on an already well described genetic pathway leading to the development of autism via zinc homeostasis is proposed. PMID:23346059

  20. Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism.

    PubMed

    Shimohata, Atsushi; Ishihara, Keiichi; Hattori, Satoko; Miyamoto, Hiroyuki; Morishita, Hiromasa; Ornthanalai, Guy; Raveau, Matthieu; Ebrahim, Abdul Shukkur; Amano, Kenji; Yamada, Kazuyuki; Sago, Haruhiko; Akiba, Satoshi; Mataga, Nobuko; Murphy, Niall P; Miyakawa, Tsuyoshi; Yamakawa, Kazuhiro

    2017-07-01

    Ts1Cje mice have a segmental trisomy of chromosome 16 that is orthologous to human chromosome 21 and display Down syndrome-like cognitive impairments. Despite the occurrence of affective and emotional impairments in patients with Down syndrome, these parameters are poorly documented in Down syndrome mouse models, including Ts1Cje mice. Here, we conducted comprehensive behavioral analyses, including anxiety-, sociability-, and depression-related tasks, and biochemical analyses of monoamines and their metabolites in Ts1Cje mice. Ts1Cje mice showed enhanced locomotor activity in novel environments and increased social contact with unfamiliar partners when compared with wild-type littermates, but a significantly lower activity in familiar environments. Ts1Cje mice also exhibited some signs of decreased depression like-behavior. Furthermore, Ts1Cje mice showed monoamine abnormalities, including increased extracellular dopamine and serotonin, and enhanced catabolism in the striatum and ventral forebrain. This study constitutes the first report of deviated monoamine metabolism that may help explain the basis for abnormal behaviors, including the environmental stimuli-triggered hyperactivity, increased sociability and decreased depression-like behavior in Ts1Cje mice. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Zinc triggers microglial activation.

    PubMed

    Kauppinen, Tiina M; Higashi, Youichirou; Suh, Sang Won; Escartin, Carole; Nagasawa, Kazuki; Swanson, Raymond A

    2008-05-28

    Microglia are resident immune cells of the CNS. When stimulated by infection, tissue injury, or other signals, microglia assume an activated, "ameboid" morphology and release matrix metalloproteinases, reactive oxygen species, and other proinflammatory factors. This innate immune response augments host defenses, but it can also contribute to neuronal death. Zinc is released by neurons under several conditions in which microglial activation occurs, and zinc chelators can reduce neuronal death in animal models of cerebral ischemia and neurodegenerative disorders. Here, we show that zinc directly triggers microglial activation. Microglia transfected with a nuclear factor-kappaB (NF-kappaB) reporter gene showed a severalfold increase in NF-kappaB activity in response to 30 microm zinc. Cultured mouse microglia exposed to 15-30 microm zinc increased nitric oxide production, increased F4/80 expression, altered cytokine expression, and assumed the activated morphology. Zinc-induced microglial activation was blocked by inhibiting NADPH oxidase, poly(ADP-ribose) polymerase-1 (PARP-1), or NF-kappaB activation. Zinc injected directly into mouse brain induced microglial activation in wild-type mice, but not in mice genetically lacking PARP-1 or NADPH oxidase activity. Endogenous zinc release, induced by cerebral ischemia-reperfusion, likewise induced a robust microglial reaction, and this reaction was suppressed by the zinc chelator CaEDTA. Together, these results suggest that extracellular zinc triggers microglial activation through the sequential activation of NADPH oxidase, PARP-1, and NF-kappaB. These findings identify a novel trigger for microglial activation and a previously unrecognized mechanism by which zinc may contribute to neurological disorders.

  2. Superconducting matrix fault current limiter with current-driven trigger mechanism

    DOEpatents

    Yuan; Xing

    2008-04-15

    A modular and scalable Matrix-type Fault Current Limiter (MFCL) that functions as a "variable impedance" device in an electric power network, using components made of superconducting and non-superconducting electrically conductive materials. An inductor is connected in series with the trigger superconductor in the trigger matrix and physically surrounds the superconductor. The current surge during a fault will generate a trigger magnetic field in the series inductor to cause fast and uniform quenching of the trigger superconductor to significantly reduce burnout risk due to superconductor material non-uniformity.

  3. Maternal exposure to carbamazepine at environmental concentrations can cross intestinal and placental barriers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kaushik, Gaurav, E-mail: kausgaur@isu.edu; Department of Medical Pathology and Laboratory Medicine, University of California at Davis, Davis, CA 95817; Institute for Pediatric Regenerative Medicine, Shriners Hospitals for Children, Northern California, 2425 Stockton Boulevard, Sacramento, CA 95817

    Psychoactive pharmaceuticals have been found as teratogens at clinical dosage during pregnancy. These pharmaceuticals have also been detected in minute (ppb) concentrations in drinking water in the US, and are environmental contaminants that may be complicit in triggering neurological disorders in genetically susceptible individuals. Previous studies have determined that psychoactive pharmaceuticals (fluoxetine, venlafaxine and carbamazepine) at environmentally relevant concentrations enriched sets of genes regulating development and function of the nervous system in fathead minnows. Altered gene sets were also associated with potential neurological disorders, including autism spectrum disorders (ASD). Subsequent in vitro studies indicated that psychoactive pharmaceuticals altered ASD-associated synaptic proteinmore » expression and gene expression in human neuronal cells. However, it is unknown if environmentally relevant concentrations of these pharmaceuticals are able to cross biological barriers from mother to fetus, thus potentially posing risks to nervous system development. The main objective of this study was to test whether psychoactive pharmaceuticals (fluoxetine, venlafaxine, and carbamazepine) administered through the drinking water at environmental concentrations to pregnant mice could reach the brain of the developing embryo by crossing intestinal and placental barriers. We addressed this question by adding {sup 2}H-isotope labeled pharmaceuticals to the drinking water of female mice for 20 days (10 pre-and 10 post–conception days), and quantifying {sup 2}H-isotope enrichment signals in the dam liver and brain of developing embryos using isotope ratio mass spectrometry. Significant levels of {sup 2}H enrichment was detected in the brain of embryos and livers of carbamazepine-treated mice but not in those of control dams, or for fluoxetine or venlafaxine application. These results provide the first evidence that carbamazepine in drinking water and

  4. Twelve tips for creating trigger images for problem-based learning cases.

    PubMed

    Azer, Samy A

    2007-03-01

    A trigger is the starting point of problem-based learning (PBL) cases. It is usually in the form of 5-6 text lines that provide the key information about the main character (usually the patient), including 3-4 of patient's presenting problems. In addition to the trigger text, most programs using PBL include a visual trigger. This might be in the form of a single image, a series of images, a video clip, a cartoon, or even one of the patient's investigation results (e.g. chest X-ray, pathology report, or urine sample analysis). The main educational objectives of the trigger image are as follows: (1) to introduce the patient to the students; (2) to enhance students' observation skills; (3) to provide them with new information to add to the cues obtained from the trigger text; and (4) to stimulate students to ask questions as they develop their enquiry plan. When planned and delivered effectively, trigger images should be engaging and stimulate group discussion. Understanding the educational objectives of using trigger images and choosing appropriate images are the keys for constructing successful PBL cases. These twelve tips highlight the key steps in the successful creation of trigger images.

  5. The CMS Level-1 Calorimeter Trigger for LHC Run II

    NASA Astrophysics Data System (ADS)

    Sinthuprasith, Tutanon

    2017-01-01

    The phase-1 upgrades of the CMS Level-1 calorimeter trigger have been completed. The Level-1 trigger has been fully commissioned and it will be used by CMS to collect data starting from the 2016 data run. The new trigger has been designed to improve the performance at high luminosity and large number of simultaneous inelastic collisions per crossing (pile-up). For this purpose it uses a novel design, the Time Multiplexed Design, which enables the data from an event to be processed by a single trigger processor at full granularity over several bunch crossings. The TMT design is a modular design based on the uTCA standard. The architecture is flexible and the number of trigger processors can be expanded according to the physics needs of CMS. Intelligent, more complex, and innovative algorithms are now the core of the first decision layer of CMS: the upgraded trigger system implements pattern recognition and MVA (Boosted Decision Tree) regression techniques in the trigger processors for pT assignment, pile up subtraction, and isolation requirements for electrons, and taus. The performance of the TMT design and the latency measurements and the algorithm performance which has been measured using data is also presented here.

  6. Trigger Warnings as Respect for Student Boundaries in University Classrooms

    ERIC Educational Resources Information Center

    Spencer, Leland G.; Kulbaga, Theresa A.

    2018-01-01

    The fierce public and scholarly debate over trigger warnings in university classrooms has often characterized the issue as one of academic freedom and ignored the social justice arguments for trigger warnings. In this essay, we argue that trigger warnings expand academic speech by engaging students more fully in their own learning. Specifically,…

  7. Hemoglobin levels triggering erythropoiesis-stimulating agent therapy in patients with cancer: the shift after United States Food and Drug Administration policy changes.

    PubMed

    Stroupe, Kevin T; Tarlov, Elizabeth; Lee, Todd A; Weichle, Thomas W; Zhang, Qiuying L; Michaelis, Laura C; Ozer, Howard; Durazo-Arvizu, Ramon; Browning, Margaret M; Hynes, Denise M

    2012-11-01

    To determine whether the hemoglobin level at which health care providers prescribed erythropoiesis-stimulating agent (ESA) therapy (trigger hemoglobin level) for their patients receiving chemotherapy was lower after the United States Food and Drug Administration (FDA) mandated a black-box warning in March 2007. Retrospective analysis. U.S. Department of Veterans Affairs Healthcare System (VA) national databases. A total of 7450 patients who were diagnosed with cancer between 2002 and 2009, were undergoing chemotherapy, and who received an ESA within 12 months after their cancer diagnosis. Data were collected on patients' demographic, clinical, environmental, and treatment-related factors. After controlling for these factors, multivariable regression analyses were used to compare the trigger hemoglobin level before and after the FDA-mandated labeling change. The average trigger hemoglobin level was 0.73 g/dl lower after the labeling change (95% confidence interval [CI] -0.84 to -0.63). Moreover, the decline in trigger hemoglobin levels began in mid-2006, when the average trigger hemoglobin level fell from 10.50 g/dl in early 2006 (95% CI 10.36-10.63) to 9.30 g/dl by late 2009 (95% CI 9.10-9.49). Even before the 2007 FDA-mandated changes in ESA product labeling, hemoglobin levels that triggered ESA treatment began declining for patients receiving cancer care within the VA. This highlights the critical importance of dissemination of postmarketing safety data to impact shifts in ESA use for anemia management. © 2012 Pharmacotherapy Publications, Inc.

  8. Sliding scale HCG trigger yields equivalent pregnancy outcomes and reduces ovarian hyperstimulation syndrome: Analysis of 10,427 IVF-ICSI cycles

    PubMed Central

    Schattman, Glenn; Davis, Owen; Rosenwaks, Zev

    2017-01-01

    Objective To evaluate pregnancy outcomes and the incidence of ovarian hyperstimulation syndrome (OHSS) using a sliding scale hCG protocol to trigger oocyte maturity and establish a threshold level of serum b-hCG associated with optimal oocyte maturity. Design Retrospective cohort. Setting Academic medical center. Patients Fresh IVF cycles from 9/2004–12/2011. Intervention 10,427 fresh IVF-ICSI cycles met inclusion criteria. hCG was administered according to E2 level at trigger: 10,000IU vs. 5,000IU vs. 4,000IU vs. 3,300IU vs. dual trigger (2mg leuprolide acetate + 1,500IU hCG). Serum absorption of hCG was assessed according to dose and BMI. Main outcome measures Oocyte maturity was analyzed according to post-trigger serum b-hCG. Fertilization, clinical pregnancy, live birth and OHSS rates were examined by hCG trigger dose. Results Post-trigger serum b-hCG 20–30, 30–40, and 40–50 mIU/mL was associated with reduced oocyte maturity as compared b-hCG >50 (67.8% vs. 71.4% vs. 73.3% vs. 78.9%, respectively, P<0.05). b-hCG 20–50 mIU/mL was associated with a 40.1% reduction in live birth (OR 0.59, 95% CI 0.41–0.87). No differences in IVF outcomes per retrieval were seen for varying doses of hCG or dual trigger when controlling for patient age. The incidence of moderate to severe OHSS was 0.13% (n = 14) and severe OHSS was 0.03% (n = 4) of cycles. Conclusions Moderate stimulation with sliding scale hCG at trigger and fresh transfer is associated with low rates of OHSS and favorable pregnancy rates. Doses as low as 3,300IU alone or dual trigger with 1,500IU are sufficient to facilitate oocyte maturity. PMID:28441461

  9. Political and environmental attitude toward participatory energy and environmental governance: A survey in post-Fukushima Japan.

    PubMed

    Nakamura, Hidenori

    2017-10-01

    The Great East Japan Earthquake and subsequent Fukushima nuclear accident triggered citizen dialogue on energy and environmental management in Japan. However, an international survey has shown that the willingness of Japanese citizens to participate in political and social activities has declined since the Fukushima accident. Employing an internet-based survey in four urban or nuclear power plant-hosting prefectures in Japan, this study examines the willingness to participate in random sampling deliberation on post-disaster energy and environmental policy. It focuses on the effects of political, environmental, and social attitudes towards willingness to participate in citizen dialogue. The survey shows around 40% of respondents may participate in energy and environmental deliberation. Statistical analysis reveals that environmental consciousness raises the propensity to participate in deliberation, while political obedience and social hesitation decreases the will to participate. The effect of environmental attitudes is larger than that of political and social attitudes. The survey also finds that governmental response to deliberation, i.e., information generation and disclosure based on requests from citizen dialogue, encourages participation in deliberation in a conservative prefecture, when citizen dialogue is held at the national level. Random sampling deliberation opens a new mode of environmental governance regardless of local political and social characteristics. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Evaluation of the Environmental Scoring System in Multiple Child Asthma Intervention Programs in Boston, Massachusetts.

    PubMed

    Dong, Zhao; Nath, Anjali; Guo, Jing; Bhaumik, Urmi; Chin, May Y; Dong, Sherry; Marshall, Erica; Murphy, Johnna S; Sandel, Megan T; Sommer, Susan J; Ursprung, W W Sanouri; Woods, Elizabeth R; Reid, Margaret; Adamkiewicz, Gary

    2018-01-01

    To test the applicability of the Environmental Scoring System, a quick and simple approach for quantitatively measuring environmental triggers collected during home visits, and to evaluate its contribution to improving asthma outcomes among various child asthma programs. We pooled and analyzed data from multiple child asthma programs in the Greater Boston Area, Massachusetts, collected in 2011 to 2016, to examine the association of environmental scores (ES) with measures of asthma outcomes and compare the results across programs. Our analysis showed that demographics were important contributors to variability in asthma outcomes and total ES, and largely explained the differences among programs at baseline. Among all programs in general, we found that asthma outcomes were significantly improved and total ES significantly reduced over visits, with the total Asthma Control Test score negatively associated with total ES. Our study demonstrated that the Environmental Scoring System is a useful tool for measuring home asthma triggers and can be applied regardless of program and survey designs, and that demographics of the target population may influence the improvement in asthma outcomes.

  11. All set, indeed! N2pc components reveal simultaneous attentional control settings for multiple target colors.

    PubMed

    Grubert, Anna; Eimer, Martin

    2016-08-01

    To study whether top-down attentional control processes can be set simultaneously for different visual features, we employed a spatial cueing procedure to measure behavioral and electrophysiological markers of task-set contingent attentional capture during search for targets defined by 1 or 2 possible colors (one-color and two-color tasks). Search arrays were preceded by spatially nonpredictive color singleton cues. Behavioral spatial cueing effects indicative of attentional capture were elicited only by target-matching but not by distractor-color cues. However, when search displays contained 1 target-color and 1 distractor-color object among gray nontargets, N2pc components were triggered not only by target-color but also by distractor-color cues both in the one-color and two-color task, demonstrating that task-set nonmatching items attracted attention. When search displays contained 6 items in 6 different colors, so that participants had to adopt a fully feature-specific task set, the N2pc to distractor-color cues was eliminated in both tasks, indicating that nonmatching items were now successfully excluded from attentional processing. These results demonstrate that when observers adopt a feature-specific search mode, attentional task sets can be configured flexibly for multiple features within the same dimension, resulting in the rapid allocation of attention to task-set matching objects only. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  12. Surgery for trigger finger.

    PubMed

    Fiorini, Haroldo Junior; Tamaoki, Marcel Jun; Lenza, Mário; Gomes Dos Santos, Joao Baptista; Faloppa, Flávio; Belloti, Joao Carlos

    2018-02-20

    Trigger finger is a common clinical disorder, characterised by pain and catching as the patient flexes and extends digits because of disproportion between the diameter of flexor tendons and the A1 pulley. The treatment approach may include non-surgical or surgical treatments. Currently there is no consensus about the best surgical treatment approach (open, percutaneous or endoscopic approaches). To evaluate the effectiveness and safety of different methods of surgical treatment for trigger finger (open, percutaneous or endoscopic approaches) in adults at any stage of the disease. We searched CENTRAL, MEDLINE, Embase and LILACS up to August 2017. We included randomised or quasi-randomised controlled trials that assessed adults with trigger finger and compared any type of surgical treatment with each other or with any other non-surgical intervention. The major outcomes were the resolution of trigger finger, pain, hand function, participant-reported treatment success or satisfaction, recurrence of triggering, adverse events and neurovascular injury. Two review authors independently selected the trial reports, extracted the data and assessed the risk of bias. Measures of treatment effect for dichotomous outcomes calculated risk ratios (RRs), and mean differences (MDs) or standardised mean differences (SMD) for continuous outcomes, with 95% confidence intervals (CIs). When possible, the data were pooled into meta-analysis using the random-effects model. GRADE was used to assess the quality of evidence for each outcome. Fourteen trials were included, totalling 1260 participants, with 1361 trigger fingers. The age of participants included in the studies ranged from 16 to 88 years; and the majority of participants were women (approximately 70%). The average duration of symptoms ranged from three to 15 months, and the follow-up after the procedure ranged from eight weeks to 23 months.The studies reported nine types of comparisons: open surgery versus steroid injections (two

  13. Dynamic stresses, Coulomb failure, and remote triggering

    USGS Publications Warehouse

    Hill, D.P.

    2008-01-01

    Dynamic stresses associated with crustal surface waves with 15-30-sec periods and peak amplitudes 5 km). The latter is consistent with the observation that extensional or transtensional tectonic regimes are more susceptible to remote triggering by Rayleigh-wave dynamic stresses than compressional or transpressional regimes. Locally elevated pore pressures may have a role in the observed prevalence of dynamic triggering in extensional regimes and geothermal/volcanic systems.

  14. Skier triggering of backcountry avalanches with skilled route selection

    NASA Astrophysics Data System (ADS)

    Sinickas, Alexandra; Haegeli, Pascal; Jamieson, Bruce

    2015-04-01

    Jamieson (2009) provided numerical estimates for the baseline probabilities of triggering an avalanche by a backcountry skier making fresh tracks without skilled route selection as a function of the North American avalanche danger scale (i.e., hazard levels Low, Moderate, Considerable, High and Extreme). Using the results of an expert survey, he showed that triggering probabilities while skiing directly up, down or across a trigger zone without skilled route selection increase roughly by a factor of 10 with each step of the North American avalanche danger scale (i.e. hazard level). The objective of the present study is to examine the effect of skilled route selection on the relationship between triggering probability and hazard level. To assess the effect of skilled route selection on triggering probability by hazard level, we analysed avalanche hazard assessments as well as reports of skiing activity and triggering of avalanches from 11 Canadian helicopter and snowcat operations during two winters (2012-13 and 2013-14). These reports were submitted to the daily information exchange among Canadian avalanche safety operations, and reflect professional decision-making and route selection practices of guides leading groups of skiers. We selected all skier-controlled or accidentally triggered avalanches with a destructive size greater than size 1 according to the Canadian avalanche size classification, triggered by any member of a guided group (guide or guest). These operations forecast the avalanche hazard daily for each of three elevation bands: alpine, treeline and below treeline. In contrast to the 2009 study, an exposure was defined as a group skiing within any one of the three elevation bands, and consequently within a hazard rating, for the day (~4,300 ratings over two winters). For example, a group that skied below treeline (rated Moderate) and treeline (rated Considerable) in one day, would receive one count for exposure to Moderate hazard, and one count for

  15. Amyotrophic lateral sclerosis and environmental factors

    PubMed Central

    Bozzoni, Virginia; Pansarasa, Orietta; Diamanti, Luca; Nosari, Guido; Cereda, Cristina; Ceroni, Mauro

    2016-01-01

    Summary Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder that affects central and peripheral motor neuron cells. Its etiology is unknown, although a relationship between genetic background and environmental factors may play a major role in triggering the neurodegeneration. In this review, we analyze the role of environmental factors in ALS: heavy metals, electromagnetic fields and electric shocks, pesticides, β-N-methylamino-L-alanine, physical activity and the controversial role of sports. The literature on the single issues is analyzed in an attempt to clarify, as clearly as possible, whether each risk factor significantly contributes to the disease pathogenesis. After summarizing conflicting observations and data, the authors provide a final synthetic statement. PMID:27027889

  16. 3.5 GHz Environmental Sensing Capability Detection Thresholds and Deployment

    PubMed Central

    Nguyen, Thao T.; Souryal, Michael R.; Sahoo, Anirudha; Hall, Timothy A.

    2017-01-01

    Spectrum sharing in the 3.5 GHz band between commercial and government users along U.S. coastal areas depends on an environmental sensing capability (ESC)—that is, a network of radio frequency sensors and a decision system—to detect the presence of incumbent shipborne radar systems and trigger protective measures, as needed. It is well known that the sensitivity of these sensors depends on the aggregate interference generated by commercial systems to the incumbent radar receivers, but to date no comprehensive study has been made of the aggregate interference in realistic scenarios and its impact on the requirement for detection of the radar signal. This paper presents systematic methods for determining the placement of ESC sensors and their detection thresholds to adequately protect incumbent shipborne radar systems from harmful interference. Using terrain-based propagation models and a population-based deployment model, the analysis finds the offshore distances at which protection must be triggered and relates these to the detection levels of coastline sensors. We further show that sensor placement is a form of the well-known set cover problem, which has been shown to be NP-complete, and demonstrate practical solutions achieved with a greedy algorithm. Results show detection thresholds to be as much as 22 dB lower than required by current industry standards. The methodology and results presented in this paper can be used by ESC operators for planning and deployment of sensors and by regulators for testing sensor performance. PMID:29303162

  17. Quantitative modeling of reservoir-triggered seismicity

    NASA Astrophysics Data System (ADS)

    Hainzl, S.; Catalli, F.; Dahm, T.; Heinicke, J.; Woith, H.

    2017-12-01

    Reservoir-triggered seismicity might occur as the response to the crustal stress caused by the poroelastic response to the weight of the water volume and fluid diffusion. Several cases of high correlations have been found in the past decades. However, crustal stresses might be altered by many other processes such as continuous tectonic stressing and coseismic stress changes. Because reservoir-triggered stresses decay quickly with distance, even tidal or rainfall-triggered stresses might be of similar size at depth. To account for simultaneous stress sources in a physically meaningful way, we apply a seismicity model based on calculated stress changes in the crust and laboratory-derived friction laws. Based on the observed seismicity, the model parameters can be determined by maximum likelihood method. The model leads to quantitative predictions of the variations of seismicity rate in space and time which can be used for hypothesis testing and forecasting. For case studies in Talala (India), Val d'Agri (Italy) and Novy Kostel (Czech Republic), we show the comparison of predicted and observed seismicity, demonstrating the potential and limitations of the approach.

  18. Trigger chemistries for better industrial formulations.

    PubMed

    Wang, Hsuan-Chin; Zhang, Yanfeng; Possanza, Catherine M; Zimmerman, Steven C; Cheng, Jianjun; Moore, Jeffrey S; Harris, Keith; Katz, Joshua S

    2015-04-01

    In recent years, innovations and consumer demands have led to increasingly complex liquid formulations. These growing complexities have provided industrial players and their customers access to new markets through product differentiation, improved performance, and compatibility/stability with other products. One strategy for enabling more complex formulations is the use of active encapsulation. When encapsulation is employed, strategies are required to effect the release of the active at the desired location and time of action. One particular route that has received significant academic research effort is the employment of triggers to induce active release upon a specific stimulus, though little has translated for industrial use to date. To address emerging industrial formulation needs, in this review, we discuss areas of trigger release chemistries and their applications specifically as relevant to industrial use. We focus the discussion on the use of heat, light, shear, and pH triggers as applied in several model polymeric systems for inducing active release. The goal is that through this review trends will emerge for how technologies can be better developed to maximize their value through industrial adaptation.

  19. Parent Trigger Policies, Representation, and the Public Good

    ERIC Educational Resources Information Center

    Allen, Ann; Saultz, Andrew

    2015-01-01

    Using theories of representation and democratic education, this article examines the impetus of parent trigger policies in the United States and their potential effects on public good goals for public education. The article also uses theories of representation and responsible democratic governance to assess the parent trigger policies, or what are…

  20. Triggering of explosive reconnection in a thick current sheet via current sheet compression: Less current sheet thinning, more temperature anisotropy

    NASA Astrophysics Data System (ADS)

    Shimizu, K.; Shinohara, I.; Fujimoto, M.

    2016-12-01

    Two-dimensional kinetic simulations of compression of thick current sheets are performed to see how it can lead to triggering of explosive magnetic reconnection. The current sheet under study is simply in a Harris-like anti-paralell and symmetric geometry. A one-dimensional pre-study shows that the compression is more effective to make the plasma anisotropy than to thin the current sheet width. When the lobe magnetic field is amplified by a factor of 2, the plasma temperature anisotropy inside the current sheet reaches 2 but the current sheet thickness is reduced only by 1/sqrt(2). If a current sheet thickness needs to be comparable to the ion inertial scale for reconnection triggering take place, as is widely and frequently mentioned in the research community, the initial thickness cannot be more than a few ion scale for reconnection to set-in. On the other hand, the temperature anisotropy of 2 can be significant for the triggering problem. Two-dimensional simulations show explosive magnetic reconnection to take place even when the initial current sheet thickness more than an order of magnitude thicker than the ion scale, indicating the resilient triggering drive supplied by the temperature anisotropy. We also discuss how the reconnection triggering capability of the temperature anisotropy boosted tearing mode for thick current sheets compares with the instabilities in the plane orthogonal to the reconnecting field.

  1. Method for triggering an action

    DOEpatents

    Hall, David R.; Bartholomew, David B.; Johnson, Monte L.; Moon, Justin; Koehler, Roger O.

    2006-10-17

    A method for triggering an action of at least one downhole device on a downhole network integrated into a downhole tool string synchronized to an event comprises determining latency, sending a latency adjusted signal, and performing the action. The latency is determined between a control device and the at least one downhole device. The latency adjusted signal for triggering an action is sent to the downhole device. The action is performed downhole synchronized to the event. A preferred method for determining latency comprises the steps: a control device sends a first signal to the downhole device; after receiving the signal, the downhole device sends a response signal to the control device; and the control device analyzes the time from sending the signal to receiving the response signal.

  2. Adaptively Adjusted Event-Triggering Mechanism on Fault Detection for Networked Control Systems.

    PubMed

    Wang, Yu-Long; Lim, Cheng-Chew; Shi, Peng

    2016-12-08

    This paper studies the problem of adaptively adjusted event-triggering mechanism-based fault detection for a class of discrete-time networked control system (NCS) with applications to aircraft dynamics. By taking into account the fault occurrence detection progress and the fault occurrence probability, and introducing an adaptively adjusted event-triggering parameter, a novel event-triggering mechanism is proposed to achieve the efficient utilization of the communication network bandwidth. Both the sensor-to-control station and the control station-to-actuator network-induced delays are taken into account. The event-triggered sensor and the event-triggered control station are utilized simultaneously to establish new network-based closed-loop models for the NCS subject to faults. Based on the established models, the event-triggered simultaneous design of fault detection filter (FDF) and controller is presented. A new algorithm for handling the adaptively adjusted event-triggering parameter is proposed. Performance analysis verifies the effectiveness of the adaptively adjusted event-triggering mechanism, and the simultaneous design of FDF and controller.

  3. Earthquake triggering in southeast Africa following the 2012 Indian Ocean earthquake

    NASA Astrophysics Data System (ADS)

    Neves, Miguel; Custódio, Susana; Peng, Zhigang; Ayorinde, Adebayo

    2018-02-01

    In this paper we present evidence of earthquake dynamic triggering in southeast Africa. We analysed seismic waveforms recorded at 53 broad-band and short-period stations in order to identify possible increases in the rate of microearthquakes and tremor due to the passage of teleseismic waves generated by the Mw8.6 2012 Indian Ocean earthquake. We found evidence of triggered local earthquakes and no evidence of triggered tremor in the region. We assessed the statistical significance of the increase in the number of local earthquakes using β-statistics. Statistically significant dynamic triggering of local earthquakes was observed at 7 out of the 53 analysed stations. Two of these stations are located in the northeast coast of Madagascar and the other five stations are located in the Kaapvaal Craton, southern Africa. We found no evidence of dynamically triggered seismic activity in stations located near the structures of the East African Rift System. Hydrothermal activity exists close to the stations that recorded dynamic triggering, however, it also exists near the East African Rift System structures where no triggering was observed. Our results suggest that factors other than solely tectonic regime and geothermalism are needed to explain the mechanisms that underlie earthquake triggering.

  4. Neural robust stabilization via event-triggering mechanism and adaptive learning technique.

    PubMed

    Wang, Ding; Liu, Derong

    2018-06-01

    The robust control synthesis of continuous-time nonlinear systems with uncertain term is investigated via event-triggering mechanism and adaptive critic learning technique. We mainly focus on combining the event-triggering mechanism with adaptive critic designs, so as to solve the nonlinear robust control problem. This can not only make better use of computation and communication resources, but also conduct controller design from the view of intelligent optimization. Through theoretical analysis, the nonlinear robust stabilization can be achieved by obtaining an event-triggered optimal control law of the nominal system with a newly defined cost function and a certain triggering condition. The adaptive critic technique is employed to facilitate the event-triggered control design, where a neural network is introduced as an approximator of the learning phase. The performance of the event-triggered robust control scheme is validated via simulation studies and comparisons. The present method extends the application domain of both event-triggered control and adaptive critic control to nonlinear systems possessing dynamical uncertainties. Copyright © 2018 Elsevier Ltd. All rights reserved.

  5. Constraints and triggers: situational mechanics of gender in negotiation.

    PubMed

    Bowles, Hannah Riley; Babcock, Linda; McGinn, Kathleen L

    2005-12-01

    The authors propose 2 categories of situational moderators of gender in negotiation: situational ambiguity and gender triggers. Reducing the degree of situational ambiguity constrains the influence of gender on negotiation. Gender triggers prompt divergent behavioral responses as a function of gender. Field and lab studies (1 and 2) demonstrated that decreased ambiguity in the economic structure of a negotiation (structural ambiguity) reduces gender effects on negotiation performance. Study 3 showed that representation role (negotiating for self or other) functions as a gender trigger by producing a greater effect on female than male negotiation performance. Study 4 showed that decreased structural ambiguity constrains gender effects of representation role, suggesting that situational ambiguity and gender triggers work in interaction to moderate gender effects on negotiation performance. Copyright 2006 APA, all rights reserved.

  6. Resource Materials To Support Your Environmental Education Efforts. EE-TIPS (Environmental Education Technical Information Packages).

    ERIC Educational Resources Information Center

    North American Association for Environmental Education, Troy, OH.

    This collection gathers together over 50 high-quality materials to support environmental education (EE) curricula. Because each community has unique environmental and educational needs, the guide includes a broad set of educational materials that can be adapted to a variety of settings. The materials can be used to supplement educational…

  7. Zinc triggers microglial activation

    PubMed Central

    Kauppinen, Tiina M.; Higashi, Youichirou; Suh, Sang Won; Escartin, Carole; Nagasawa, Kazuki; Swanson, Raymond A.

    2009-01-01

    Microglia are resident immune cells of the central nervous system. When stimulated by infection, tissue injury, or other signals, microglia assume an activated, “amoeboid” morphology and release matrix metalloproteinases, reactive oxygen species, and other pro-inflammatory factors. This innate immune response augments host defenses, but it can also contribute to neuronal death. Zinc is released by neurons under several conditions in which microglial activation occurs, and zinc chelators can reduce neuronal death in animal models of cerebral ischemia and neurodegenerative disorders. Here we show that zinc directly triggers microglial activation. Microglia transfected with an NF-kB reporter gene showed a several-fold increase in NF-kB activity in response to 30 μM zinc. Cultured mouse microglia exposed to 15 – 30 μM zinc increased nitric oxide production, increased F4/80 expression, altered cytokine expression, and assumed the activated morphology. Zinc-induced microglial activation was blocked by inhibiting NADPH oxidase, poly(ADP-ribose) polymerase-1 (PARP-1), or NF-κB activation. Zinc injected directly into mouse brain induced microglial activation in wild-type mice, but not in mice genetically lacking PARP-1 or NADPH oxidase activity. Endogenous zinc release, induced by cerebral ischemia-reperfusion, likewise induced a robust microglial reaction, and this reaction was suppressed by the zinc chelator CaEDTA. Together, these results suggest that extracellular zinc triggers microglial activation through the sequential activation of NADPH oxidase, PARP-1, and NF-κB. These findings identify a novel trigger for microglial activation and a previously unrecognized mechanism by which zinc may contribute to neurological disorders. PMID:18509044

  8. An Alternative Flight Software Trigger Paradigm: Applying Multivariate Logistic Regression to Sense Trigger Conditions Using Inaccurate or Scarce Information

    NASA Technical Reports Server (NTRS)

    Smith, Kelly M.; Gay, Robert S.; Stachowiak, Susan J.

    2013-01-01

    In late 2014, NASA will fly the Orion capsule on a Delta IV-Heavy rocket for the Exploration Flight Test-1 (EFT-1) mission. For EFT-1, the Orion capsule will be flying with a new GPS receiver and new navigation software. Given the experimental nature of the flight, the flight software must be robust to the loss of GPS measurements. Once the high-speed entry is complete, the drogue parachutes must be deployed within the proper conditions to stabilize the vehicle prior to deploying the main parachutes. When GPS is available in nominal operations, the vehicle will deploy the drogue parachutes based on an altitude trigger. However, when GPS is unavailable, the navigated altitude errors become excessively large, driving the need for a backup barometric altimeter to improve altitude knowledge. In order to increase overall robustness, the vehicle also has an alternate method of triggering the parachute deployment sequence based on planet-relative velocity if both the GPS and the barometric altimeter fail. However, this backup trigger results in large altitude errors relative to the targeted altitude. Motivated by this challenge, this paper demonstrates how logistic regression may be employed to semi-automatically generate robust triggers based on statistical analysis. Logistic regression is used as a ground processor pre-flight to develop a statistical classifier. The classifier would then be implemented in flight software and executed in real-time. This technique offers improved performance even in the face of highly inaccurate measurements. Although the logistic regression-based trigger approach will not be implemented within EFT-1 flight software, the methodology can be carried forward for future missions and vehicles.

  9. An Alternative Flight Software Trigger Paradigm: Applying Multivariate Logistic Regression to Sense Trigger Conditions using Inaccurate or Scarce Information

    NASA Technical Reports Server (NTRS)

    Smith, Kelly M.; Gay, Robert S.; Stachowiak, Susan J.

    2013-01-01

    In late 2014, NASA will fly the Orion capsule on a Delta IV-Heavy rocket for the Exploration Flight Test-1 (EFT-1) mission. For EFT-1, the Orion capsule will be flying with a new GPS receiver and new navigation software. Given the experimental nature of the flight, the flight software must be robust to the loss of GPS measurements. Once the high-speed entry is complete, the drogue parachutes must be deployed within the proper conditions to stabilize the vehicle prior to deploying the main parachutes. When GPS is available in nominal operations, the vehicle will deploy the drogue parachutes based on an altitude trigger. However, when GPS is unavailable, the navigated altitude errors become excessively large, driving the need for a backup barometric altimeter. In order to increase overall robustness, the vehicle also has an alternate method of triggering the drogue parachute deployment based on planet-relative velocity if both the GPS and the barometric altimeter fail. However, this velocity-based trigger results in large altitude errors relative to the targeted altitude. Motivated by this challenge, this paper demonstrates how logistic regression may be employed to automatically generate robust triggers based on statistical analysis. Logistic regression is used as a ground processor pre-flight to develop a classifier. The classifier would then be implemented in flight software and executed in real-time. This technique offers excellent performance even in the face of highly inaccurate measurements. Although the logistic regression-based trigger approach will not be implemented within EFT-1 flight software, the methodology can be carried forward for future missions and vehicles.

  10. Home is Where the Triggers Are: Increasing Asthma Control by Improving the Home Environment.

    PubMed

    Krieger, James

    2010-06-01

    Asthma remains the most common chronic condition of childhood. Strong evidence has linked exposure to allergens and other triggers commonly found in homes to allergen sensitization and asthma incidence and morbidity. A growing body of evidence has demonstrated that a home visit strategy that includes an environmental component that addresses multiple triggers through multiple interventions is effective. Such home visits reduce exposure to triggers, decrease symptoms and urgent health-care use, and increase quality of life. To make home visits widely available will require health-care payor reimbursement, government and health plan funding, training and certification of home visitors, and active referrals from health-care providers. However, a strategy based solely on education and behavior change is limited, because it cannot adequately reduce exposures due to adverse housing conditions. Therefore, approaches that address substandard housing are needed. These include remediation of existing housing and construction of new asthma-friendly homes. Most studies of remediation have made relatively narrow and focused improvements, such as insulation, heating, or ventilation. Outcomes have been mixed. Studies of new asthma-friendly homes are in their infancy, with promising pilot data. Further investigation is needed to establish the effectiveness of improving housing. A final strategy is improving housing quality through policy change, such as implementation of healthy housing guidelines for new construction, enhancement and increased enforcement of housing codes, and assuring smoke-free multi-unit homes. The combination of home visits, improved housing construction, and policy change has great potential for reducing the global burden of asthma.

  11. Mitochondrial dysfunction as a trigger of innate immune responses and inflammation.

    PubMed

    West, A Phillip

    2017-11-01

    A growing literature indicates that mitochondria are key participants in innate immune pathways, functioning as both signaling platforms and contributing to effector responses. In addition to regulating antiviral signaling and antibacterial immunity, mitochondria are also important drivers of inflammation caused by sterile injury. Much research on mitochondrial control of immunity now centers on understanding how mitochondrial constituents released during cellular damage simulate the innate immune system. When mitochondrial integrity is compromised, mitochondrial damage-associated molecular patterns engage pattern recognition receptors, trigger inflammation, and promote pathology in an expanding list of diseases. Here, I review the emerging knowledge of mitochondrial dysfunction in innate immune responses and discuss how environmental exposures may induce mitochondrial damage to potentiate inflammation and human disease. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Glacigenic sedimentation pulses triggered post-glacial gas hydrate dissociation.

    PubMed

    Karstens, Jens; Haflidason, Haflidi; Becker, Lukas W M; Berndt, Christian; Rüpke, Lars; Planke, Sverre; Liebetrau, Volker; Schmidt, Mark; Mienert, Jürgen

    2018-02-12

    Large amounts of methane are stored in continental margins as gas hydrates. They are stable under high pressure and low, but react sensitively to environmental changes. Bottom water temperature and sea level changes were considered as main contributors to gas hydrate dynamics after the last glaciation. However, here we show with numerical simulations that pulses of increased sedimentation dominantly controlled hydrate stability during the end of the last glaciation offshore mid-Norway. Sedimentation pulses triggered widespread gas hydrate dissociation and explains the formation of ubiquitous blowout pipes in water depths of 600 to 800 m. Maximum gas hydrate dissociation correlates spatially and temporally with the formation or reactivation of pockmarks, which is constrained by radiocarbon dating of Isorropodon nyeggaensis bivalve shells. Our results highlight that rapid changes of sedimentation can have a strong impact on gas hydrate systems affecting fluid flow and gas seepage activity, slope stability and the carbon cycle.

  13. Surface-wave potential for triggering tectonic (nonvolcanic) tremor

    USGS Publications Warehouse

    Hill, D.P.

    2010-01-01

    Source processes commonly posed to explain instances of remote dynamic triggering of tectonic (nonvolcanic) tremor by surface waves include frictional failure and various modes of fluid activation. The relative potential for Love- and Rayleigh-wave dynamic stresses to trigger tectonic tremor through failure on critically stressed thrust and vertical strike-slip faults under the Coulomb-Griffith failure criteria as a function of incidence angle is anticorrelated over the 15- to 30-km-depth range that hosts tectonic tremor. Love-wave potential is high for strike-parallel incidence on low-angle reverse faults and null for strike-normal incidence; the opposite holds for Rayleigh waves. Love-wave potential is high for both strike-parallel and strike-normal incidence on vertical, strike-slip faults and minimal for ~45?? incidence angles. The opposite holds for Rayleigh waves. This pattern is consistent with documented instances of tremor triggered by Love waves incident on the Cascadia mega-thrust and the San Andreas fault (SAF) in central California resulting from shear failure on weak faults (apparent friction, ????? 0.2). However, documented instances of tremor triggered by surface waves with strike-parallel incidence along the Nankai megathrust beneath Shikoku, Japan, is associated primarily with Rayleigh waves. This is consistent with the tremor bursts resulting from mixed-mode failure (crack opening and shear failure) facilitated by near-lithostatic ambient pore pressure, low differential stress, with a moderate friction coefficient (?? ~ 0.6) on the Nankai subduction interface. Rayleigh-wave dilatational stress is relatively weak at tectonic tremor source depths and seems unlikely to contribute significantly to the triggering process, except perhaps for an indirect role on the SAF in sustaining tremor into the Rayleigh-wave coda that was initially triggered by Love waves.

  14. Testing for the 'predictability' of dynamically triggered earthquakes in The Geysers geothermal field

    NASA Astrophysics Data System (ADS)

    Aiken, Chastity; Meng, Xiaofeng; Hardebeck, Jeanne

    2018-03-01

    The Geysers geothermal field is well known for being susceptible to dynamic triggering of earthquakes by large distant earthquakes, owing to the introduction of fluids for energy production. Yet, it is unknown if dynamic triggering of earthquakes is 'predictable' or whether dynamic triggering could lead to a potential hazard for energy production. In this paper, our goal is to investigate the characteristics of triggering and the physical conditions that promote triggering to determine whether or not triggering is in anyway foreseeable. We find that, at present, triggering in The Geysers is not easily 'predictable' in terms of when and where based on observable physical conditions. However, triggered earthquake magnitude positively correlates with peak imparted dynamic stress, and larger dynamic stresses tend to trigger sequences similar to mainshock-aftershock sequences. Thus, we may be able to 'predict' what size earthquakes to expect at The Geysers following a large distant earthquake.

  15. Antarctic icequakes triggered by the 2010 Maule earthquake in Chile

    NASA Astrophysics Data System (ADS)

    Peng, Zhigang; Walter, Jacob I.; Aster, Richard C.; Nyblade, Andrew; Wiens, Douglas A.; Anandakrishnan, Sridhar

    2014-09-01

    Seismic waves from distant, large earthquakes can almost instantaneously trigger shallow micro-earthquakes and deep tectonic tremor as they pass through Earth's crust. Such remotely triggered seismic activity mostly occurs in tectonically active regions. Triggered seismicity is generally considered to reflect shear failure on critically stressed fault planes and is thought to be driven by dynamic stress perturbations from both Love and Rayleigh types of surface seismic wave. Here we analyse seismic data from Antarctica in the six hours leading up to and following the 2010 Mw 8.8 Maule earthquake in Chile. We identify many high-frequency seismic signals during the passage of the Rayleigh waves generated by the Maule earthquake, and interpret them as small icequakes triggered by the Rayleigh waves. The source locations of these triggered icequakes are difficult to determine owing to sparse seismic network coverage, but the triggered events generate surface waves, so are probably formed by near-surface sources. Our observations are consistent with tensile fracturing of near-surface ice or other brittle fracture events caused by changes in volumetric strain as the high-amplitude Rayleigh waves passed through. We conclude that cryospheric systems can be sensitive to large distant earthquakes.

  16. Influence of supraliminal reward information on unconsciously triggered response inhibition.

    PubMed

    Diao, Liuting; Ding, Cody; Qi, Senqing; Zeng, Qinghong; Huang, Bo; Xu, Mengsi; Fan, Lingxia; Yang, Dong

    2014-01-01

    Although executive functions (e.g., response inhibition) are often thought to interact consciously with reward, recent studies have demonstrated that they can also be triggered by unconscious stimuli. Further research has suggested a close relationship between consciously and unconsciously triggered response inhibition. To date, however, the effect of reward on unconsciously triggered response inhibition has not been explored. To address this issue, participants in this study performed runs of a modified Go/No-Go task during which they were exposed to both high and low value monetary rewards presented both supraliminally and subliminally. Participants were informed that they would earn the reward displayed if they responded correctly to each trial of the run. According to the results, when rewards were presented supraliminally, a greater unconsciously triggered response inhibition was observed for high-value rewards than for low-value rewards. In contrast, when rewards were presented subliminally, no enhanced unconsciously triggered response inhibition was observed. Results revealed that supraliminal and subliminal rewards have distinct effects on unconsciously triggered response inhibition. These findings have important implications for extending our understanding of the relationship between reward and response inhibition.

  17. Influence of Supraliminal Reward Information on Unconsciously Triggered Response Inhibition

    PubMed Central

    Diao, Liuting; Ding, Cody; Qi, Senqing; Zeng, Qinghong; Huang, Bo; Xu, Mengsi; Fan, Lingxia; Yang, Dong

    2014-01-01

    Although executive functions (e.g., response inhibition) are often thought to interact consciously with reward, recent studies have demonstrated that they can also be triggered by unconscious stimuli. Further research has suggested a close relationship between consciously and unconsciously triggered response inhibition. To date, however, the effect of reward on unconsciously triggered response inhibition has not been explored. To address this issue, participants in this study performed runs of a modified Go/No-Go task during which they were exposed to both high and low value monetary rewards presented both supraliminally and subliminally. Participants were informed that they would earn the reward displayed if they responded correctly to each trial of the run. According to the results, when rewards were presented supraliminally, a greater unconsciously triggered response inhibition was observed for high-value rewards than for low-value rewards. In contrast, when rewards were presented subliminally, no enhanced unconsciously triggered response inhibition was observed. Results revealed that supraliminal and subliminal rewards have distinct effects on unconsciously triggered response inhibition. These findings have important implications for extending our understanding of the relationship between reward and response inhibition. PMID:25268227

  18. Triggers and monitoring in intelligent personal health record.

    PubMed

    Luo, Gang

    2012-10-01

    Although Web-based personal health records (PHRs) have been widely deployed, the existing ones have limited intelligence. Previously, we introduced expert system technology and Web search technology into the PHR domain and proposed the concept of an intelligent PHR (iPHR). iPHR provides personalized healthcare information to facilitate users' daily activities of living. The current iPHR is passive and follows the pull model of information distribution. This paper introduces triggers and monitoring into iPHR to make iPHR become active. Our idea is to let medical professionals pre-compile triggers and store them in iPHR's knowledge base. Each trigger corresponds to an abnormal event that may have potential medical impact. iPHR keeps collecting, processing, and analyzing the user's medical data from various sources such as wearable sensors. Whenever an abnormal event is detected from the user's medical data, the corresponding trigger fires and the related personalized healthcare information is pushed to the user using natural language generation technology, expert system technology, and Web search technology.

  19. A search for non-triggered events in the BATSE data base

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kommers, J. M.; Lewin, W. H. G.; Kouveliotou, C.

    1998-05-16

    The archival data from BATSE permit a search for transients that did not activate the onboard burst trigger. Examples of such non-triggered events include faint gamma-ray bursts (GRBs), emission from soft gamma-ray repeaters (SGRs), and bursts and flares from X-ray binaries. A GRB may fail to trigger onboard because it is too faint, because it occurs while the onboard trigger is disabled, or because it biases the onboard background estimation. We describe a search of the BATSE archival data that is sensitive to GRBs with peak fluxes fainter by a factor of {approx}2 than those detected with the onboard burstmore » trigger (on the 1.024 s time scale)« less

  20. Cluster observations and simulations of He+ EMIC triggered emissions

    NASA Astrophysics Data System (ADS)

    Grison, B.; Shoji, M.; Santolik, O.; Omura, Y.

    2012-12-01

    EMIC triggered emissions have been reported in the inner magnetosphere at the edge of the plasmapause nightside [Pickett et al., 2010]. The generation mechanism proposed by Omura et al. [2010] is very similar to the one of the whistler chorus emissions and simulation results agree with observations and theory [Shoji et Omura, 2011]. The main characteristics of these emissions generated in the magnetic equatorial plane region are a frequency with time dispersion and a high level of coherence. The start frequency of previously mentioned observations is above half of the proton gyrofrequency. It means that the emissions are generated on the proton branch. On the He+ branch, generation of triggered emissions, in the same region, requests more energetic protons and the triggering process starts below the He+ gyrofrequency. It makes their identification in Cluster data rather difficult. Recent simulation results confirm the possibility of EMIC triggered emission on the He+ branch. In the present contribution we propose to compare a Cluster event to simulation results in order to investigate the possibility to identify observations to a He+ triggered emission. The impact of the observed waves on particle precipitation is also investigated.

  1. Standard setting processes and regulations for environmental contaminants in drinking water: State versus federal needs and viewpoints

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sidhu, K.S.

    1991-06-01

    The primary objective of a standard setting process is to arrive at a drinking water concentration at which exposure to a contaminant would result in no known or potential adverse health effect on human health. The drinking water standards also serve as guidelines to prevent pollution of water sources and may be applicable in some cases as regulatory remediation levels. The risk assessment methods along with various decision making parameters are used to establish drinking water standards. For carcinogens classified in Groups A and B by the United States Environmental Protection Agency (USEPA) the standards are set by using nonthresholdmore » cancer risk models. The linearized multistage model is commonly used for computation of potency factors for carcinogenic contaminants. The acceptable excess risk level may vary from 10(-6) to 10(-4). For noncarcinogens, a threshold model approach based on application of an uncertainty factor is used to arrive at a reference dose (RfD). The RfD approach may also be used for carcinogens classified in Group C by the USEPA. The RfD approach with an additional uncertainty factory of 10 for carcinogenicity has been applied in the formulation of risk assessment for Group C carcinogens. The assumptions commonly used in arriving at drinking water standards are human life expectancy, 70 years; average human body weight, 70 kg; human daily drinking water consumption, 2 liters; and contribution of exposure to the contaminant from drinking water (expressed as a part of the total environmental exposure), 20%. Currently, there are over 80 USEPA existing or proposed primary standards for organic and inorganic contaminants in drinking water. Some of the state versus federal needs and viewpoints are discussed.« less

  2. AUDIS wear: a smartwatch based assistive device for ubiquitous awareness of environmental sounds.

    PubMed

    Mielke, Matthias; Bruck, Rainer

    2016-08-01

    A multitude of assistive devices is available for deaf people (i.e. deaf, deafened, and hard of hearing). Besides hearing and communication aids, devices to access environmental sounds are available commercially. But the devices have two major drawbacks: 1. they are targeted at indoor environments (e.g. home or work), and 2. only specific events are supported (e.g. the doorbell or telephone). Recent research shows that important sounds can occur in all contexts and that the interests in sounds are diverse. These drawbacks can be tackled by using modern information and communication technology that enables the development of new and improved assistive devices. The smartwatch, a new computing platform in the form of a wristwatch, offers new potential for assistive technology. Its design promises a perfect integration into various different social contexts and thus blends perfectly into the user's life. Based on a smartwatch and algorithms from pattern recognition, a prototype for awareness of environmental sounds is presented here. It observes the acoustic environment of the user and detects environmental sounds. A vibration is triggered when a sound is detected and the type of sound is shown on the display. The design of the prototype was discussed with deaf people in semi-structured interviews, leading to a set of implications for the design of such a device.

  3. Analysis of a potential trigger of an acute illness.

    PubMed

    Becker, Niels G; Salim, Agus; Kelman, Christopher W

    2006-01-01

    Sometimes certain short-term risk exposures are postulated to act as a trigger for the onset of a specific acute illness. When the incidence of the illness is low it is desirable to investigate this possible association using only data on cases detected during a specific observation period. Here we propose an analysis for such a study based on a model expressed in terms of the probability that the exposure triggers the illness and a random delay from a triggered illness until its diagnosis. Both the natural hazard rate for the illness and the probability that the exposure triggers the illness are assumed to be small and possibly dependent on age and covariates such as sex and duration or severity of the exposure. The method of analysis is illustrated with a study of the association between long flights and hospitalization for venous thromboembolism.

  4. Peculiarity and vulnerability of karst settings, analyzed through a review of available environmental indices

    NASA Astrophysics Data System (ADS)

    Parise, Mario; Mazzei, Marianna

    2016-04-01

    Karst is a unique environment on Earth, characterized by a variety of peculiar geological and hydrological features, that are expressed by typical landforms at the surface (doline, ponor, polje, etc.) and underground (single cave, sinkhole, complex hypogean systems consisting of sequences of pits and galleries, etc.). Among the main characters of karst, the direct connection between the surface and the underground is at the origin of the fragility of karst settings, and the related high vulnerability. Many different types of natural geological hazards (or geo-hazards) may potentially affect karst lands, with sinkholes and flash floods being the most frequent and typical. In addition, karst is exposed to a variety of anthropogenic disturbances as well, including loss of natural landscapes, destruction of caves and speleothems, and contamination and pollution problems. At this latter regard, it has to be reminded that karst aquifers host high quality groundwaters, that are used as source of drinking water worldwide, with estimates indicating that the supply of drinking water from karst is going to have a significant increase in the next decades, From all of this, the importance in fully defining the karst setting, and in a detail examination of all the natural and anthropogenic events that may cause negative effects on it, comes out. Uniqueness of karst has been acknowledged since a long time, but only in recent years efforts have been made to develop approaches and methods specifically dedicated to this peculiar environment. Such approaches represent definitely a mandatory step in the correct management of karst terranes, providing useful elements to stakeholders, land managers and people living in karst lands about their fragility, and the need to safeguard them and the natural resources therein contained. Starting from these considerations, in this contribution we review the main environmental indices dedicated to karst that have been recently proposed in the

  5. A z-Vertex Trigger for Belle II

    NASA Astrophysics Data System (ADS)

    Skambraks, S.; Abudinén, F.; Chen, Y.; Feindt, M.; Frühwirth, R.; Heck, M.; Kiesling, C.; Knoll, A.; Neuhaus, S.; Paul, S.; Schieck, J.

    2015-08-01

    The Belle II experiment will go into operation at the upgraded SuperKEKB collider in 2016. SuperKEKB is designed to deliver an instantaneous luminosity L = 8 ×1035 cm - 2 s - 1. The experiment will therefore have to cope with a much larger machine background than its predecessor Belle, in particular from events outside of the interaction region. We present the concept of a track trigger, based on a neural network approach, that is able to suppress a large fraction of this background by reconstructing the z (longitudinal) position of the event vertex within the latency of the first level trigger. The trigger uses the hit information from the Central Drift Chamber (CDC) of Belle II within narrow cones in polar and azimuthal angle as well as in transverse momentum (“sectors”), and estimates the z-vertex without explicit track reconstruction. The preprocessing for the track trigger is based on the track information provided by the standard CDC trigger. It takes input from the 2D track finder, adds information from the stereo wires of the CDC, and finds the appropriate sectors in the CDC for each track. Within the sector, the z-vertex is estimated by a specialized neural network, with the drift times from the CDC as input and a continuous output corresponding to the scaled z-vertex. The neural algorithm will be implemented in programmable hardware. To this end a Virtex 7 FPGA board will be used, which provides at present the most promising solution for a fully parallelized implementation of neural networks or alternative multivariate methods. A high speed interface for external memory will be integrated into the platform, to be able to store the O(109) parameters required. The contribution presents the results of our feasibility studies and discusses the details of the envisaged hardware solution.

  6. CO2-Triggered Switchable Solvents, Surfactants, and Other Materials

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jessop, Philip G.; Mercer, Sean; Heldebrant, David J.

    2012-06-14

    Waste CO2 at atmospheric pressure can be used to trigger dramatic changes in the properties of certain switchable materials. Compared to other triggers such as light, acids, oxidants, CO2 has the advantages that it is inexpensive, nonhazardous, non-accumulating in the system, easily removed, and it does not require the material to be transparent. Known CO2-triggered switchable materials 10 now include solvents, surfactants, solutes, catalysts, particles, polymers, and gels. The added flexibility of switchable materials represents a new strategy for minimizing energy and material consumption in process and product design.

  7. The CMS Level-1 trigger for LHC Run II

    NASA Astrophysics Data System (ADS)

    Tapper, A.

    2018-02-01

    During LHC Run II the centre-of-mass energy of pp collisions has increased from 8 TeV up to 13 TeV and the instantaneous luminosity has progressed towards 2 × 1034 cm-2s-1. In order to guarantee a successful and ambitious physics programme under these conditions, the CMS trigger system has been upgraded. The upgraded CMS Level-1 trigger is designed to improve performance at high luminosity and large number of simultaneous inelastic collisions per crossing. The trigger design, implementation and commissioning are summarised, and performance results are described.

  8. Testing for the ‘predictability’ of dynamically triggered earthquakes in Geysers Geothermal Field

    USGS Publications Warehouse

    Aiken, Chastity; Meng, Xiaofeng; Hardebeck, Jeanne L.

    2018-01-01

    The Geysers geothermal field is well known for being susceptible to dynamic triggering of earthquakes by large distant earthquakes, owing to the introduction of fluids for energy production. Yet, it is unknown if dynamic triggering of earthquakes is ‘predictable’ or whether dynamic triggering could lead to a potential hazard for energy production. In this paper, our goal is to investigate the characteristics of triggering and the physical conditions that promote triggering to determine whether or not triggering is in anyway foreseeable. We find that, at present, triggering in The Geysers is not easily ‘predictable’ in terms of when and where based on observable physical conditions. However, triggered earthquake magnitude positively correlates with peak imparted dynamic stress, and larger dynamic stresses tend to trigger sequences similar to mainshock–aftershock sequences. Thus, we may be able to ‘predict’ what size earthquakes to expect at The Geysers following a large distant earthquake.

  9. Setting of index system of environmental and economic accounting of water

    NASA Astrophysics Data System (ADS)

    Tan, Yarong

    2017-10-01

    To realize the quality advancement of integrated water management in China, a scientific and perfect index system of environmental and economic accounting should be built. At present, the water shortage in China becomes increasingly serious, which further highlights the importance of efficient water management and improving the index system of water economic accounting. Based on the internal structure of the new statistical method of environmental and economic accounting, this paper focuses on analyzing and discussing the index system which it should have.

  10. A Radiation-Triggered Surveillance System for UF6 Cylinder Monitoring

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Curtis, Michael M.; Myjak, Mitchell J.

    This report provides background information and representative scenarios for testing a prototype radiation-triggered surveillance system at an operating facility that handles uranium hexafluoride (UF 6) cylinders. The safeguards objective is to trigger cameras using radiation, or radiation and motion, rather than motion alone, to reduce significantly the number of image files generated by a motion-triggered system. The authors recommend the use of radiation-triggered surveillance at all facilities where cylinder paths are heavily traversed by personnel. The International Atomic Energy Agency (IAEA) has begun using surveillance cameras in the feed and withdrawal areas of gas centrifuge enrichment plants (GCEPs). The camerasmore » generate imagery using elapsed time or motion, but this creates problems in areas occupied 24/7 by personnel. Either motion-or-interval-based triggering generates thousands of review files over the course of a month. Since inspectors must review the files to verify operator material-flow-declarations, a plethora of files significantly extends the review process. The primary advantage of radiation-triggered surveillance is the opportunity to obtain full-time cylinder throughput verification versus what presently amounts to part-time verification. Cost savings should be substantial, as the IAEA presently uses frequent unannounced inspections to verify cylinder-throughput declarations. The use of radiation-triggered surveillance allows the IAEA to implement less frequent unannounced inspections for the purpose of flow verification, but its principal advantage is significantly shorter and more effective inspector video reviews.« less

  11. Unraveling earthquake stresses: Insights from dynamically triggered and induced earthquakes

    NASA Astrophysics Data System (ADS)

    Velasco, A. A.; Alfaro-Diaz, R. A.

    2017-12-01

    Induced seismicity, earthquakes caused by anthropogenic activity, has more than doubled in the last several years resulting from practices related to oil and gas production. Furthermore, large earthquakes have been shown to promote the triggering of other events within two fault lengths (static triggering), due to static stresses caused by physical movement along the fault, and also remotely from the passage of seismic waves (dynamic triggering). Thus, in order to understand the mechanisms for earthquake failure, we investigate regions where natural, induced, and dynamically triggered events occur, and specifically target Oklahoma. We first analyze data from EarthScope's USArray Transportable Array (TA) and local seismic networks implementing an optimized (STA/LTA) detector in order to develop local detection and earthquake catalogs. After we identify triggered events through statistical analysis, and perform a stress analysis to gain insight on the stress-states leading to triggered earthquake failure. We use our observations to determine the role of different transient stresses in contributing to natural and induced seismicity by comparing these stresses to regional stress orientation. We also delineate critically stressed regions of triggered seismicity that may indicate areas susceptible to earthquake hazards associated with sustained fluid injection in provinces of induced seismicity. Anthropogenic injection and extraction activity can alter the stress state and fluid flow within production basins. By analyzing the stress release of these ancient faults caused by dynamic stresses, we may be able to determine if fluids are solely responsible for increased seismic activity in induced regions.

  12. Observations of bi-directional leader development in a triggered lightning flash

    NASA Technical Reports Server (NTRS)

    Laroche, P.; Idone, V.; Eybert-Berard, A.; Barret, L.

    1991-01-01

    Observations of a modified form of rocket triggered lightning are described. A flash triggered during the summer of 1989 is studied as part of an effort to model bidirectional discharge. It is suggested that the altitude triggering technique provides a realistic means of studying the attachment process.

  13. Innovative Techniques for Teaching about Landslides and Triggered Landslide Events

    NASA Astrophysics Data System (ADS)

    Taylor, F. E.; Malamud, B. D.

    2014-12-01

    When we think of a landslide (mass wasting), both the public and scientists often envisage an individual movement of earth material down a slope. Yet, landslides often occur not as individuals, but as parts of a triggered landslide event. This is where a trigger (e.g., an earthquake or heavy rainfall) results in up to tens of thousands of landslides in a region in the minutes to days after the trigger. In this paper, we will present ideas for innovative demonstrations, teaching practicals and projects, ranging from low-cost low-tech to more advanced digital methods, to communicate the ideas of landslides and triggered landslide events to the public and students. This paper is aimed at those in secondary school/university education and the public sector looking for examples to interest and inform their respective audiences about landslides, triggered landslide events, and the importance and implications of considering landslides not just as individuals, but as populations.

  14. Decentralized event-triggered synchronization of uncertain Markovian jumping neutral-type neural networks with mixed delays.

    PubMed

    Senan, Sibel; Syed Ali, M; Vadivel, R; Arik, Sabri

    2017-02-01

    In this study, we present an approach for the decentralized event-triggered synchronization of Markovian jumping neutral-type neural networks with mixed delays. We present a method for designing decentralized event-triggered synchronization, which only utilizes locally available information, in order to determine the time instants for transmission from sensors to a central controller. By applying a novel Lyapunov-Krasovskii functional, as well as using the reciprocal convex combination method and some inequality techniques such as Jensen's inequality, we obtain several sufficient conditions in terms of a set of linear matrix inequalities (LMIs) under which the delayed neural networks are stochastically stable in terms of the error systems. Finally, we conclude that the drive systems synchronize stochastically with the response systems. We show that the proposed stability criteria can be verified easily using the numerically efficient Matlab LMI toolbox. The effectiveness and feasibility of the results obtained are verified by numerical examples. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Alcohol and vagal tone as triggers for paroxysmal atrial fibrillation.

    PubMed

    Mandyam, Mala C; Vedantham, Vasanth; Scheinman, Melvin M; Tseng, Zian H; Badhwar, Nitish; Lee, Byron K; Lee, Randall J; Gerstenfeld, Edward P; Olgin, Jeffrey E; Marcus, Gregory M

    2012-08-01

    Alcohol and vagal activity may be important triggers for paroxysmal atrial fibrillation (PAF), but it remains unknown if these associations occur more often than would be expected by chance alone because of the lack of a comparator group in previous studies. We compared self-reported frequency of these triggers in patients with PAF to those with other supraventricular tachycardias (SVTs). Consecutive consenting patients presenting for electrophysiology procedures at a single university medical center underwent a structured interview regarding arrhythmia triggers. Two hundred twenty-three patients with a documented arrhythmia (133 with PAF and 90 with SVT) completed the survey. After multivariable adjustment, patients with PAF had a 4.42 greater odds (95% confidence interval [CI] 1.35 to 14.44) of reporting alcohol consumption (p = 0.014) and a 2.02 greater odds (95% CI 1.02 to 4.00) of reporting vagal activity (p = 0.044) as an arrhythmia trigger compared to patients with SVT. In patients with PAF, drinking primarily beer was associated with alcohol as a trigger (odds ratio [OR] 4.49, 95% CI 1.41 to 14.28, p = 0.011), whereas younger age (OR 0.68, 95% CI 0.49 to 0.95, p = 0.022) and a family history of AF (OR 5.73, 95% CI 1.21 to 27.23, p = 0.028) each were independently associated with having vagal activity provoke an episode. Patients with PAF and alcohol triggers were more likely to have vagal triggers (OR 10.32, 95% CI 1.05 to 101.42, p = 0.045). In conclusion, alcohol consumption and vagal activity elicit PAF significantly more often than SVT. Alcohol and vagal triggers often were found in the same patients with PAF, raising the possibility that alcohol may precipitate AF by vagal mechanisms. Copyright © 2012 Elsevier Inc. All rights reserved.

  16. Research on multi-switch synchronization based on single trigger generator

    NASA Astrophysics Data System (ADS)

    Geng, Jiuyuan; Cheng, Xinbing; Yang, Jianhua; Yang, Xiao; Chen, Rong

    2018-05-01

    Multi-switch synchronous operation is an effective approach to provide high-voltage high-current for a high-power device. In this paper, we present a synchronization system with a corona stabilized triggered switch (CSTS) as main switch and an all-solid modularized quasi-square pulse forming system. In addition, this paper provides explanations of low jitter and accurate triggering of CSTS based on streamer theory. Different switches of the module are triggered by an electrical pulse created by a trigger generator, a quasi-square pulse can be created on the load. The experimental results show that it is able to switch voltages in excess of 40kV with nanosecond system jitter for three-module synchronous operation.

  17. Acute exacerbation of idiopathic pulmonary fibrosis triggered by Aspergillus empyema.

    PubMed

    Suzuki, Atsushi; Kimura, Tomoki; Kataoka, Kensuke; Matsuda, Toshiaki; Yokoyama, Toshiki; Mori, Yuta; Kondoh, Yasuhiro

    2018-01-01

    Acute exacerbation (AE) is a severe and life-threatening complication of idiopathic pulmonary fibrosis (IPF). In 2016, the definition and diagnostic criteria for AE-IPF were updated by an international working group. The new definition includes any acute, clinically significant respiratory deterioration (both idiopathic and triggered events) characterized by evidence of new widespread alveolar abnormality in patients with IPF. There are no currently proven beneficial management strategies for idiopathic and triggered AE-IPF. This is the first report describing AE-IPF triggered by Aspergillus empyema, which was improved by a combination of corticosteroid, systemic antifungal therapy, local antifungal therapy, and additional pharmacological therapies. Future research may reveal optimal strategies for both idiopathic and triggered AE-IPF.

  18. Triggering for Magnetic Field Measurements of the LCLS Undulators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hacker, Kirsten

    A triggering system for magnetic field measurements of the LCLS undulators has been built with a National Instruments PXI-1002 and a Xylinx FPGA board. The system generates single triggers at specified positions, regardless of encoder sensor jitter about a linear scale.

  19. Alcohol's effect on triggered displaced aggression.

    PubMed

    Aviles, Fredy; Earleywine, Mitchell; Pollock, Vicki; Stratton, Joy; Miller, Norman

    2005-03-01

    The authors examined alcohol's effect on triggered displaced aggression, the hostile reaction to a second provoking person after provocation from a first. Participants consumed an alcoholic or a nonalcoholic beverage. Subsequently, one individual provoked all of them with moderate intensity. Then, 2 groups were studied: those who received or who failed to receive a second provocation of minimal intensity. Consistent with prior research, participants who received a second, minimal provocation displayed more aggression than those who did not. After participants drank alcohol, the magnitude of this difference was significantly greater, indicating that alcohol increases triggered displaced aggression. Copyright (c) 2005 APA, all rights reserved.

  20. Note: Design and investigation of a multichannel plasma-jet triggered gas switch.

    PubMed

    Tie, Weihao; Liu, Xuandong; Zhang, Qiaogen; Liu, Shanhong

    2014-07-01

    We described the fabrication and testing of a multichannel plasma-jet triggered gas switch (MPJTGS). A novel six-channel annular micro-plasma-gun was embedded in the trigger electrode to generate multichannel plasma jets as a nanosecond trigger pulse arrived. The gas breakdown in multiple sites of the spark gap was induced and fixed around jet orifices by the plasma jets. We tested the multichannel discharge characteristics of the MPJTGS in two working modes with charge voltage of 50 kV, trigger voltage of +40 kV (25 ns rise time), and trigger energy of 240 J, 32 J, and 2 J, respectively, at different working coefficients. Results show that the average number of discharge channels increased as the trigger energy increased, and decreased as the working coefficient decreased. At a working coefficient of 87.1% and trigger energy of 240 J, the average number of discharge channels in Mode II could reach 4.1.

  1. ATLAS jet trigger update for the LHC run II

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Delgado, A. T.

    The CERN Large Hadron Collider is the biggest and most powerful particle collider ever built. It produces up to 40 million proton-proton collisions per second at unprecedented energies to explore the fundamental laws and properties of Nature. The ATLAS experiment is one of the detectors that analyses and records these collisions. It generates dozens of GB/s of data that has to be reduced before it can be permanently stored, the event selection is made by the ATLAS trigger system, which reduces the data volume by a factor of 105. The trigger system has to be highly configurable in order tomore » adapt to changing running conditions and maximize the physics output whilst keeping the output rate under control. A particularly interesting pattern generated during collisions consists of a collimated spray of particles, known as a hadronic jet. To retain the interesting jets and efficiently reject the overwhelming background, optimal jet energy resolution is needed. Therefore the Jet trigger software requires CPU-intensive reconstruction algorithms. In order to reduce the resources needed for the reconstruction step, a partial detector readout scheme was developed, which effectively suppresses the low activity regions of the calorimeter. In this paper we describe the overall ATLAS trigger software, and the jet trigger in particular, along with the improvements made on the system. We then focus on detailed studies of the algorithm timing and the performance impact of the full and partial calorimeter readout schemes. We conclude with an outlook of the jet trigger plans for the next LHC data-taking period. (authors)« less

  2. Red blood cell transfusion triggers in acute leukemia: a randomized pilot study.

    PubMed

    DeZern, Amy E; Williams, Katherine; Zahurak, Marianna; Hand, Wesley; Stephens, R Scott; King, Karen E; Frank, Steven M; Ness, Paul M

    2016-07-01

    Red blood cell (RBC) transfusion thresholds have yet to be examined in large randomized trials in hematologic malignancies. This pilot study in acute leukemia uses a restrictive compared to a liberal transfusion strategy. A randomized (2:1) study was conducted of restrictive (LOW) hemoglobin (Hb) trigger (7 g/dL) compared to higher (HIGH) Hb trigger (8 g/dL). The primary outcome was feasibility of conducting a larger trial. The four requirements for success required that more than 50% of the eligible patients could be consented, more than 75% of the patients randomized to the LOW arm tolerated the transfusion trigger, fewer than 15% of patients crossed over from the LOW arm to the HIGH arm, and no indication for the need to pause the study for safety concerns. Secondary outcomes included fatigue, bleeding, and RBCs and platelets transfused. Ninety patients were consented and randomly assigned to LOW to HIGH. The four criteria for the primary objective of feasibility were met. When the number of units transfused was compared, adjusting for baseline Hb, the LOW arm was transfused on average 8.0 (95% confidence interval [CI], 6.9-9.1) units/patient while the HIGH arm received 11.7 (95% CI, 10.1-13.2) units (p = 0.0003). There was no significant difference in bleeding events or neutropenic fevers between study arms. This study establishes feasibility for trial of Hb thresholds in leukemia through demonstration of success in all primary outcome metrics and a favorable safety profile. This population requires further study to evaluate the equivalence of liberal and restrictive transfusion thresholds in this unique clinical setting. © 2016 AABB.

  3. A Photogate Flash Trigger and a Demonstration of Inertia.

    ERIC Educational Resources Information Center

    Winters, Loren

    1992-01-01

    Describes a photogate electronic flash trigger that synchronizes flash discharge with high-speed events. Presents a photographic study of a high-speed collision demonstrating the passage of a BB through an elastic strip. Provides the schematic of the delay circuit utilized in the trigger. (MDH)

  4. The preliminary development and testing of a global trigger tool to detect error and patient harm in primary-care records.

    PubMed

    de Wet, C; Bowie, P

    2009-04-01

    A multi-method strategy has been proposed to understand and improve the safety of primary care. The trigger tool is a relatively new method that has shown promise in American and secondary healthcare settings. It involves the focused review of a random sample of patient records using a series of "triggers" that alert reviewers to potential errors and previously undetected adverse events. To develop and test a global trigger tool to detect errors and adverse events in primary-care records. Trigger tool development was informed by previous research and content validated by expert opinion. The tool was applied by trained reviewers who worked in pairs to conduct focused audits of 100 randomly selected electronic patient records in each of five urban general practices in central Scotland. Review of 500 records revealed 2251 consultations and 730 triggers. An adverse event was found in 47 records (9.4%), indicating that harm occurred at a rate of one event per 48 consultations. Of these, 27 were judged to be preventable (42%). A further 17 records (3.4%) contained evidence of a potential adverse event. Harm severity was low to moderate for most patients (82.9%). Error and harm rates were higher in those aged > or =60 years, and most were medication-related (59%). The trigger tool was successful in identifying undetected patient harm in primary-care records and may be the most reliable method for achieving this. However, the feasibility of its routine application is open to question. The tool may have greater utility as a research rather than an audit technique. Further testing in larger, representative study samples is required.

  5. A hardware fast tracker for the ATLAS trigger

    NASA Astrophysics Data System (ADS)

    Asbah, Nedaa

    2016-09-01

    The trigger system of the ATLAS experiment is designed to reduce the event rate from the LHC nominal bunch crossing at 40 MHz to about 1 kHz, at the design luminosity of 1034 cm-2 s-1. After a successful period of data taking from 2010 to early 2013, the LHC already started with much higher instantaneous luminosity. This will increase the load on High Level Trigger system, the second stage of the selection based on software algorithms. More sophisticated algorithms will be needed to achieve higher background rejection while maintaining good efficiency for interesting physics signals. The Fast TracKer (FTK) is part of the ATLAS trigger upgrade project. It is a hardware processor that will provide, at every Level-1 accepted event (100 kHz) and within 100 microseconds, full tracking information for tracks with momentum as low as 1 GeV. Providing fast, extensive access to tracking information, with resolution comparable to the offline reconstruction, FTK will help in precise detection of the primary and secondary vertices to ensure robust selections and improve the trigger performance. FTK exploits hardware technologies with massive parallelism, combining Associative Memory ASICs, FPGAs and high-speed communication links.

  6. PBC triggers in water reservoirs, coal mining areas and waste disposal sites: from Newcastle to New York.

    PubMed

    Smyk, Daniel; Mytilinaiou, Maria G; Rigopoulou, Eirini I; Bogdanos, Dimitrios P

    2010-01-01

    Various environmental factors have been proposed as triggers of primary biliary cirrhosis (PBC), a progressive autoimmune cholestatic liver disease which is characterised by the destruction of the small intrahepatic bile ducts. Support for their pathogenic role in PBC is provided by epidemiological studies reporting familial clustering and clusters of the disease within a given geographical area. The seminal study by Triger reporting that the great majority of PBC cases in the English city of Sheffield drank water from a specific water reservoir, has been followed by studies reporting disease 'hot spots' within a restricted geographic region of the former coal mining area of Newcastle. The New York study reporting an increased risk and significant clustering of PBC cases near toxic federal waste disposal sites has added strength to the notion that environmental factors, possibly in the form of infectious agents or toxic/chemical environmental factors in areas of contaminated land, water or polluted air may play a key role in the development of the disease. This review discusses the findings of reports investigating environmental factors which may contribute to the cause of primary biliary cirrhosis.

  7. Role of environmental pollution in irritable bowel syndrome.

    PubMed

    Marynowski, Mateusz; Likońska, Aleksandra; Zatorski, Hubert; Fichna, Jakub

    2015-10-28

    Irritable bowel syndrome (IBS), with the prevalence of 10%-20 % of the population has become an emerging problem worldwide. IBS is a functional gastrointestinal (GI) disorder characterized by abdominal pain or discomfort and altered bowel habits. The etiology of IBS contains genetic, psychological, and immunological factors, and has not been fully elucidated; of note, recent studies also point at environmental pollution and its role in the development of functional GI diseases. In this review we focus on several environmental factors, such as bacterial contamination, air pollution, radiation and even stress as potential triggers of IBS. We discuss associated disturbances in homeostasis, such as changes in intestinal microbiome and related pathophysiological mechanisms. Based on the effect of environmental factors on the GI tract, we also propose novel targets in IBS treatment.

  8. Role of environmental pollution in irritable bowel syndrome

    PubMed Central

    Marynowski, Mateusz; Likońska, Aleksandra; Zatorski, Hubert; Fichna, Jakub

    2015-01-01

    Irritable bowel syndrome (IBS), with the prevalence of 10%-20 % of the population has become an emerging problem worldwide. IBS is a functional gastrointestinal (GI) disorder characterized by abdominal pain or discomfort and altered bowel habits. The etiology of IBS contains genetic, psychological, and immunological factors, and has not been fully elucidated; of note, recent studies also point at environmental pollution and its role in the development of functional GI diseases. In this review we focus on several environmental factors, such as bacterial contamination, air pollution, radiation and even stress as potential triggers of IBS. We discuss associated disturbances in homeostasis, such as changes in intestinal microbiome and related pathophysiological mechanisms. Based on the effect of environmental factors on the GI tract, we also propose novel targets in IBS treatment. PMID:26523104

  9. "Cold air" and/or "talking" as cough triggers, a sign for the diagnosis of cough variant asthma.

    PubMed

    Kanemitsu, Yoshihiro; Matsumoto, Hisako; Osman, Nuriamina; Oguma, Tsuyoshi; Nagasaki, Tadao; Izuhara, Yumi; Ito, Isao; Tajiri, Tomoko; Iwata, Toshiyuki; Niimi, Akio; Mishima, Michiaki

    2016-11-01

    Fractional exhaled nitric oxide (FeNO) is considered an alternative marker of eosinophilic airway inflammation and is sometimes incorporated in the diagnosis of asthma. However, many patients with cough variant asthma (CVA) demonstrate an FeNO in the normal range. Therefore, additional information is needed to confirm the diagnosis of CVA, particularly in patients with low FeNO levels. We aimed to investigate the feasibility of using cough triggers to help diagnose CVA. We studied 163 patients presenting with prolonged/chronic cough alone (including 104 CVA patients) who underwent FeNO measurements and an airway responsiveness test, and answered a questionnaire listing 18 cough triggers. The sensitivity and specificity of FeNO levels and cough triggers for the diagnosis of CVA were determined. CVA patients showed higher FeNO levels than non-CVA patients. When the cut-off value of FeNO levels for the diagnosis of CVA was set at 22ppb, its sensitivity was 57%. CVA patients more frequently responded to "cold air" and "talking" as cough triggers than non-CVA patients. When the analysis was confined to those with a low FeNO (<22ppb) group, the sensitivity and positive predictive values of "cold air" and "talking" for the diagnosis of CVA were 36% and 70% for "cold air", and 44% and 74% for "talking", respectively. Their specificity was 81%. "Cold air" was associated with airway hyperresponsiveness in all patients with an emphasis on those with low FeNO levels. "Cold air" and/or "talking" as cough triggers could be signs for the diagnosis of CVA, particularly when FeNO levels are low. Copyright © 2016 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.

  10. Distributed Event-Based Set-Membership Filtering for a Class of Nonlinear Systems With Sensor Saturations Over Sensor Networks.

    PubMed

    Ma, Lifeng; Wang, Zidong; Lam, Hak-Keung; Kyriakoulis, Nikos

    2017-11-01

    In this paper, the distributed set-membership filtering problem is investigated for a class of discrete time-varying system with an event-based communication mechanism over sensor networks. The system under consideration is subject to sector-bounded nonlinearity, unknown but bounded noises and sensor saturations. Each intelligent sensing node transmits the data to its neighbors only when certain triggering condition is violated. By means of a set of recursive matrix inequalities, sufficient conditions are derived for the existence of the desired distributed event-based filter which is capable of confining the system state in certain ellipsoidal regions centered at the estimates. Within the established theoretical framework, two additional optimization problems are formulated: one is to seek the minimal ellipsoids (in the sense of matrix trace) for the best filtering performance, and the other is to maximize the triggering threshold so as to reduce the triggering frequency with satisfactory filtering performance. A numerically attractive chaos algorithm is employed to solve the optimization problems. Finally, an illustrative example is presented to demonstrate the effectiveness and applicability of the proposed algorithm.

  11. Conjunction of factors triggering waves of seasonal influenza

    PubMed Central

    Chattopadhyay, Ishanu; Kiciman, Emre; Elliott, Joshua W; Shaman, Jeffrey L

    2018-01-01

    Using several longitudinal datasets describing putative factors affecting influenza incidence and clinical data on the disease and health status of over 150 million human subjects observed over a decade, we investigated the source and the mechanistic triggers of influenza epidemics. We conclude that the initiation of a pan-continental influenza wave emerges from the simultaneous realization of a complex set of conditions. The strongest predictor groups are as follows, ranked by importance: (1) the host population’s socio- and ethno-demographic properties; (2) weather variables pertaining to specific humidity, temperature, and solar radiation; (3) the virus’ antigenic drift over time; (4) the host population’€™s land-based travel habits, and; (5) recent spatio-temporal dynamics, as reflected in the influenza wave auto-correlation. The models we infer are demonstrably predictive (area under the Receiver Operating Characteristic curve 80%) when tested with out-of-sample data, opening the door to the potential formulation of new population-level intervention and mitigation policies. PMID:29485041

  12. Conjunction of factors triggering waves of seasonal influenza.

    PubMed

    Chattopadhyay, Ishanu; Kiciman, Emre; Elliott, Joshua W; Shaman, Jeffrey L; Rzhetsky, Andrey

    2018-02-27

    Using several longitudinal datasets describing putative factors affecting influenza incidence and clinical data on the disease and health status of over 150 million human subjects observed over a decade, we investigated the source and the mechanistic triggers of influenza epidemics. We conclude that the initiation of a pan-continental influenza wave emerges from the simultaneous realization of a complex set of conditions. The strongest predictor groups are as follows, ranked by importance: (1) the host population's socio- and ethno-demographic properties; (2) weather variables pertaining to specific humidity, temperature, and solar radiation; (3) the virus' antigenic drift over time; (4) the host population'€™s land-based travel habits, and; (5) recent spatio-temporal dynamics, as reflected in the influenza wave auto-correlation. The models we infer are demonstrably predictive (area under the Receiver Operating Characteristic curve 80%) when tested with out-of-sample data, opening the door to the potential formulation of new population-level intervention and mitigation policies. © 2018, Chattopadhyay et al.

  13. Optically triggered fire set/detonator system

    DOEpatents

    Chase, Jay B.; Pincosy, Philip A.; Chato, Donna M.; Kirbie, Hugh; James, Glen F.

    2007-03-20

    The present invention is directed to a system having a plurality of capacitor discharge units (CDUs) that includes electrical bridge type detonators operatively coupled to respective explosives. A pulse charging circuit is adapted to provide a voltage for each respective capacitor in each CDU. Such capacitors are discharged through the electrical bridge type detonators upon receiving an optical signal to detonate respective operatively coupled explosives at substantially the same time.

  14. A Contingency-Oriented Approach to Understanding Borderline Personality Disorder: Situational Triggers and Symptoms

    PubMed Central

    Miskewicz, Kelly; Fleeson, William; Arnold, Elizabeth Mayfield; Law, Mary Kate; Mneimne, Malek; Furr, R. Michael

    2015-01-01

    This article tested a contingency-oriented perspective to examine the dynamic relationships between in-the-moment borderline personality disorder (BPD) symptom events and in-the-moment triggers. An experience sampling study with 282 adults, including 77 participants with BPD, obtained reports of situational triggers and BPD symptom events five times daily for two weeks. Triggers included being rejected, betrayed, abandoned, offended, disappointed, having one’s self-concept threatened, being in a boring situation, and being alone. BPD was associated with increased situational triggers. Multilevel models revealed significant within-person associations between situational triggers and BPD symptoms for the average participant in the study, with significant individual variance in the strength and direction of trigger-symptom contingencies. Most trigger-symptom contingencies were stronger for individuals with higher borderline symptomatology, suggesting that triggers are meaningfully related to BPD. These findings highlight possible proximal mechanisms that maintain BPD and help explain the course of a disorder often described as chaotic and unpredictable. PMID:26200848

  15. Investigation of high-voltage pulse trigger generator based on photo-conductive semiconductor switch

    NASA Astrophysics Data System (ADS)

    Chu, Xu; Liu, Jin-Liang; Wang, Lang-Ning; Qiu, Yong-Feng

    2018-06-01

    The trigger to generate high-voltage pulse is one of the most important parts in a pulsed-power system, especially for the conduction characteristics of the main switch. However, traditional triggers usually have the drawbacks of large structure and worse long-term working stability, which goes against the demands of pulsed-power system miniaturization and stability. In the paper, a pulse trigger using photo-conductive semiconductor switch was developed, which is of small size, stable performance and steep leading edge of the output pulse rise. It is found that the output trigger pulse rise time is 14 ns, and the jitter of 20 shots is 330 ps. Applying the designed pulsed trigger in a field distortion switch and a triggered vacuum switch, experiments show that the switches could be triggered stably with reduced jitter.

  16. Magnesium-based photocathodes for triggering back-lighted thyratrons

    NASA Astrophysics Data System (ADS)

    Sozer, Esin B.

    This dissertation presents experimental studies of application of magnesium-based photocathodes to optically triggered pseudospark switches, called back-lighted thyratrons (BLTs). Magnesium was chosen as a low work function metal photocathode for its potential to increase triggering performance of the switch with a higher photoemission performance than traditional BLT cathodes. Improvement in triggering performance of plasma switches is of interest for device development of compact pulsed power systems where the size of switching units can limit the overall size and the mobility of the system. Experiments were conducted on photoemission performance of photocathode candidates under BLT-relevant conditions; and delay and jitter performance of a BLT with photocathode candidates with changing helium pressure and switch voltages. A review of photocathode literature showed that Mg and Cu are the most promising candidates for increasing the photoemission during the triggering of BLTs. As a commonly used BLT cathode in the switch literature, Mo was chosen together with Mg and Cu to be tested under BLT-relevant pressure and field conditions. Quantum efficiency measurements of high-purity foils of Mg, Cu and Mo showed a superior performance of Mg and Cu over Mo. Mg had the highest quantum efficiency of 1.5 x 10-5 among all three materials. After photoemission measurements in a test bed were concluded, testing of these cathodes for their switching performance was done in two stages. First, an unfocused UV laser beam (8.5 x 106 W/cm 2) with a wavelength of 266 nm was used for delay measurements of a BLT with Mg, Cu and Mo-based cathodes. Mg-based cathodes showed at least a thirty-fold reduction in delay and jitter compared to Cu-based and at least an eighty-fold reduction in delay and jitter compared to Mo-based cathodes at any given helium pressure and switch voltage pair. Subsequently, a partial focusing of the same light source was utilized (7.4 x 107W/cm 2) for delay

  17. Studying Triggers for Interest and Engagement Using Observational Methods

    ERIC Educational Resources Information Center

    Renninger, K. Ann; Bachrach, Jessica E.

    2015-01-01

    In this article, we discuss the contribution of observational methods to understanding the processes involved in triggering interest and establishing engagement. We begin by reviewing the literatures on interest and engagement, noting their similarities, differences, and the utility to each of better understanding the triggering process. We then…

  18. Information for Government Agencies about Specific Environmental Health Issues in Child-Care Settings

    EPA Pesticide Factsheets

    research on child care environmental health issues, identify key state and regional healthy child care organizations for partnerships, and see how other states are addressing child care environmental health issues.

  19. MicroTCA-based Global Trigger Upgrade project for the CMS experiment at LHC

    NASA Astrophysics Data System (ADS)

    Rahbaran, B.; Arnold, B.; Bergauer, H.; Eichberger, M.; Rabady, D.

    2011-12-01

    The electronics of the first Level Global Trigger (GT) of CMS is the last stage of the Level-1 trigger system [1]. At LHC up to 40 million collisions of proton bunches occur every second, resulting in about 800 million proton collisions. The CMS Level-1 Global Trigger [1], a custom designed electronics system based on FPGA technology and the VMEbus system, performs a quick on-line analysis of each collision every 25 ns and decides whether to reject or to accept it for further analysis. The CMS trigger group of the Institute of High Energy Physics in Vienna (HEPHY) is involved in the Level-1 trigger of the CMS experiment at CERN. As part of the Trigger Upgrade, the Level-1 Global Trigger will be redesigned and implemented in MicroTCA based technology, which allows engineers to detect all possible faults on plug-in boards, in the power supply and in the cooling system. The upgraded Global Trigger will be designed to have the same basic categories of functions as the present GT, but will have more algorithms and more possibilities for combining trigger candidates. Additionally, reconfigurability and testability will be supported based on the next system generation.

  20. A self-triggered picoinjector in microfluidics

    NASA Astrophysics Data System (ADS)

    Yang, Yiming; Liu, Songsheng; Jia, Chunping; Mao, Hongju; Jin, Qinghui; Zhao, Jianlong; Zhou, Hongbo

    2016-12-01

    Droplet-based microfluidics has recently emerged as a potential platform for studies of single-cell, directed evolution, and genetic sequencing. In droplet-based microfluidics, adding reagents into drops is one of the most important functions. In this paper, we develop a new self-triggered picoinjector to add controlled volumes of reagent into droplets at kilohertz rates. In the picoinjector, the reagent injecting is triggered by the coming droplet itself, without needing a droplet detection module. Meanwhile, the dosing volume can be precisely controlled. These features make the system more practical and reliable. We expect the new picoinjector will find important applications of droplet-based microfluidics in automated biological assay, directed evolution, enzyme assay, and so on.

  1. Checkpoint triggering in a computer system

    DOEpatents

    Cher, Chen-Yong

    2016-09-06

    According to an aspect, a method for triggering creation of a checkpoint in a computer system includes executing a task in a processing node of the computer system and determining whether it is time to read a monitor associated with a metric of the task. The monitor is read to determine a value of the metric based on determining that it is time to read the monitor. A threshold for triggering creation of the checkpoint is determined based on the value of the metric. Based on determining that the value of the metric has crossed the threshold, the checkpoint including state data of the task is created to enable restarting execution of the task upon a restart operation.

  2. Environmental migration and conflict dynamics: focus on developing regions.

    PubMed

    Swain, A

    1996-12-01

    The world's population is increasing by 90-100 million every year, and it may double during the next half-century, with most of the added population coming from developing countries. 700 million people are malnourished and 40,000 die of hunger and hunger-related diseases each day. Most of the developing countries are extremely dependent on their renewable resource base to sustain their economic activities. Therefore, environmental changes and the loss of resources has dire implications for developing countries. This includes loss of arable land and lack of water, which lead to decreased food production. An area of about 1.2 billion hectares (almost the size of China and India taken together) has endured modest to severe soil degradation since World War II because of human activity. Air pollution can also directly affect crop production, lowering crop, wheat, soybean, and peanut harvests in the US. Rapid climate change triggered by the greenhouse effect would also inflict disproportionately more suffering on developing countries. The rise in sea levels caused by climatic change may severely affect densely populated coastal areas in China, Egypt, and Bangladesh. The loss of living space and livelihood could lead to the migration of people as it has happened throughout human history. The definition of environmental migrants is controversial and the other terms used include environmental refugees, ecological refugees, and resource refugees. Economic migrants are those who move to economically affluent regions responding to both the push and pull factors. In contrast, environmental migrants are forced to move--as a result of the loss of livelihood and space--to the nearest possible location. The scarcity induced by environmental migration may lead to acute conflict at three levels in the developing society: state vs. state (large-scale trans-border migration may trigger armed conflicts); state vs. group (rapid urbanization); and group vs. group (nativism).

  3. Popular sweetner sucralose as a migraine trigger.

    PubMed

    Patel, Rajendrakumar M; Sarma, Rakesh; Grimsley, Edwin

    2006-09-01

    Sucralose (trichlorogalactosucrose, or better known as Splenda) is an artificial sweetener from native sucrose that was approved by the FDA on April 1, 1998 (April Fool's Day). This observation of a potential causal relationship between sucralose and migraines may be important for physicians to remember this can be a possible trigger during dietary history taking. Identifying further triggers for migraine headaches, in this case sucralose, may help alleviate some of the cost burden (through expensive medical therapy or missed work opportunity) as well as provide relief to migraineurs.

  4. Observing earthquakes triggered in the near field by dynamic deformations

    USGS Publications Warehouse

    Gomberg, J.; Bodin, P.; Reasenberg, P.A.

    2003-01-01

    We examine the hypothesis that dynamic deformations associated with seismic waves trigger earthquakes in many tectonic environments. Our analysis focuses on seismicity at close range (within the aftershock zone), complementing published studies of long-range triggering. Our results suggest that dynamic triggering is not confined to remote distances or to geothermal and volcanic regions. Long unilaterally propagating ruptures may focus radiated dynamic deformations in the propagation direction. Therefore, we expect seismicity triggered dynamically by a directive rupture to occur asymmetrically, with a majority of triggered earthquakes in the direction of rupture propagation. Bilaterally propagating ruptures also may be directive, and we propose simple criteria for assessing their directivity. We compare the inferred rupture direction and observed seismicity rate change following 15 earthquakes (M 5.7 to M 8.1) that occured in California and Idaho in the United States, the Gulf of Aqaba, Syria, Guatemala, China, New Guinea, Turkey, Japan, Mexico, and Antarctica. Nine of these mainshocks had clearly directive, unilateral ruptures. Of these nine, seven apparently induced an asymmetric increase in seismicity rate that correlates with the rupture direction. The two exceptions include an earthquake preceded by a comparable-magnitude event on a conjugate fault and another for which data limitations prohibited conclusive results. Similar (but weaker) correlations were found for the bilaterally rupturing earthquakes we studied. Although the static stress change also may trigger seismicity, it and the seismicity it triggers are expected to be similarly asymmetric only if the final slip is skewed toward the rupture terminus. For several of the directive earthquakes, we suggest that the seismicity rate change correlates better with the dynamic stress field than the static stress change.

  5. Using Water-Testing Data Sets.

    ERIC Educational Resources Information Center

    Varrella, Gary F.

    1994-01-01

    Advocates an approach to teaching environmentally related studies based on constructivism. Presents an activity that makes use of data on chemicals in the water supply, and discusses obtaining and using data sets in the classroom. (LZ)

  6. A Simulation of the Front End Signal Digitization for the ATLAS Muon Spectrometer thin RPC trigger upgrade project

    NASA Astrophysics Data System (ADS)

    Meng, Xiangting; Chapman, John; Levin, Daniel; Dai, Tiesheng; Zhu, Junjie; Zhou, Bing; Um Atlas Group Team

    2016-03-01

    The ATLAS Muon Spectrometer Phase-I (and Phase-II) upgrade includes the BIS78 muon trigger detector project: two sets of eight very thin Resistive Place Chambers (tRPCs) combined with small Monitored Drift Tube (MDT) chambers in the pseudorapidity region 1<| η|<1.3. The tRPCs will be comprised of triplet readout layer in each of the eta and azimuthal phi coordinates, with about 400 readout strips per layer. The anticipated hit rate is 100-200 kHz per strip. Digitization of the strip signals will be done by 32-channel CERN HPTDC chips. The HPTDC is a highly configurable ASIC designed by the CERN Microelectronics group. It can work in both trigger and trigger-less modes, be readout in parallel or serially. For Phase-I operation, a stringent latency requirement of 43 bunch crossings (1075 ns) is imposed. The latency budget for the front end digitization must be kept to a minimal value, ideally less than 350 ns. We conducted detailed HPTDC latency simulations using the Behavioral Verilog code from the CERN group. We will report the results of these simulations run for the anticipated detector operating environment and for various HPTDC configurations.

  7. Numerical simulation of whistler-triggered VLF emissions observed in Antartica

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nunn, D.; Smith, A.J.

    1996-03-01

    The authors have extracted from VLF databases from British Antarctica Survey data taken at Halley and Faraday stations, examples of whistler-triggered emissions (WTE). The WTE are relatively narrow band emissions triggered by natural background whistlers undergoing nonlinear wave particle interactions generally in the equatorial regions. They occur with either rising or falling frequency relative to the triggering waves. Using a Vlasov type code the authors are able to simulate the types of emissions which are observed. 24 refs., 8 figs., 3 tabs.

  8. hCG Triggering in ART: An Evolutionary Concept.

    PubMed

    Hershko Klement, Anat; Shulman, Adrian

    2017-05-17

    Human chorionic gonadotropin (hCG) is no longer a single, omnipotent ovulation triggering option. Gonadotropin releasing hormone (GnRH) agonist, initially presented as a substitute for hCG, has led to a new era of administering GnRH agonist followed by hCG triggering. According to this new concept, GnRH agonist enables successful ovum maturation, while hCG supports the luteal phase and pregnancy until placental shift.

  9. Investigating the Environmental Effects of Ocean Energy Generation (Invited)

    NASA Astrophysics Data System (ADS)

    Copping, A. E.; Anderson, R.; Schultz, I.; Woodruff, D.; Carlson, T.; Ward, J.; van Cleve, F.; Eere Mhk Environmental Effects

    2010-12-01

    The production of electricity from the moving waters of the ocean has the potential to be a viable addition to the portfolio of renewable energy sources worldwide. The marine and hydrokinetic (MHK) industry seeks to deploy and operate devices that harvest energy from the tides, waves, ocean currents and run of the river. Challenges facing the emerging industry include technology development, rigors of offshore deployments, and financing; however, the barrier most commonly cited by industry, regulators, and stakeholders is the uncertainty surrounding potential environmental effects of devices placed in the water and the permitting processes associated with those impacts. There is a need to evaluate the extensive list of potential interactions that may cause harm to marine organisms and ecosystems, to set priorities for regulatory triggers, and to direct future research. Project developers need information to understand how to minimize environmental effects; regulators need to know what monitoring targets are needed near ocean energy farms; and stakeholders need to know what mitigation strategies are effective in addressing unavoidable impacts. Scientists from Pacific Northwest National Laboratory (PNNL) are developing an Environmental Risk Evaluation System (ERES) to assess environmental effects associated with MHK technologies and projects through a systematic analytical process, with specific input from key stakeholder groups. The ERES development process provides the scientific structure to support risk characterization, comparison of tradeoffs, and risk-informed decision-making by project and technology developers, regulatory agencies, and other interested stakeholders. The PNNL team will determine the range and severity of environmental effects of MHK development, leading to the development of mitigation strategies where residual risk remains. Input to ERES draws from a wide range of marine and freshwater studies to understand which marine receptors may suffer

  10. Using Reflection Triggers while Learning in an Online Course

    ERIC Educational Resources Information Center

    Verpoorten, Dominique; Westera, Wim; Specht, Marcus

    2012-01-01

    This paper reports on a controlled experiment on the effects of three types of reflection triggers in an online course. Fifty-four volunteers, distributed in five groups, used these structured opportunities for reflection during learning. Results show that reflection triggers were extensively employed by the test persons and were perceived as…

  11. Triggered plasma opening switch

    DOEpatents

    Mendel, Clifford W.

    1988-01-01

    A triggerable opening switch for a very high voltage and current pulse includes a transmission line extending from a source to a load and having an intermediate switch section including a plasma for conducting electrons between transmission line conductors and a magnetic field for breaking the plasma conduction path and magnetically insulating the electrons when it is desired to open the switch.

  12. [Anesthesia unrelated triggering of a fatal malignant hyperthermia crisis].

    PubMed

    Olthoff, D; Vonderlind, C

    1997-12-01

    For incidents of malignant hyperthermia (MH) outside the hospital, a high number of unrecorded cases must be reckoned with because of an insufficient knowledge of emergency services and poor identification and documentation that make it impossible to classify acute situations under the diagnosis of malignant hyperthermia crisis. As a result, there are no statistical data in this field, and only case reports with a broad spectrum of suspected trigger mechanisms have been published. The case described in this report is a proved example of a non-anesthesia-related triggering of MH in a 21-year-old man who had had an anesthetic-induced MH manifestation in childhood, which was confirmed with an in vitro contracture test. After visiting a restaurant, he became unconscious and convulsive after consuming a high level of alcohol (2.9/1000). The first cardiocirculatory arrest occurred directly before hospitalization. After admission, the patient showed a full-blown MH episode whose subsequent fatality was unavoidable in spite of adapted and optimal therapy. Suspected trigger mechanisms seem to be multifactoral (excessive alcohol consumption, over-heating, mental stress) as a forensic investigation did not point to any particular signs of typical trigger substances. The case demonstrates again that an MH attack might be triggered under certain non-anaesthesia-related situations. For patients with an MH disposition, additional information on their behavior outside the hospital is required.

  13. Theory and observation of electromagnetic ion cyclotron triggered emissions in the magnetosphere

    NASA Astrophysics Data System (ADS)

    Omura, Yoshiharu; Pickett, Jolene; Grison, Benjamin; Santolik, Ondrej; Dandouras, Iannis; Engebretson, Mark; Décréau, Pierrette M. E.; Masson, Arnaud

    2010-07-01

    We develop a nonlinear wave growth theory of electromagnetic ion cyclotron (EMIC) triggered emissions observed in the inner magnetosphere. We first derive the basic wave equations from Maxwell's equations and the momentum equations for the electrons and ions. We then obtain equations that describe the nonlinear dynamics of resonant protons interacting with an EMIC wave. The frequency sweep rate of the wave plays an important role in forming the resonant current that controls the wave growth. Assuming an optimum condition for the maximum growth rate as an absolute instability at the magnetic equator and a self-sustaining growth condition for the wave propagating from the magnetic equator, we obtain a set of ordinary differential equations that describe the nonlinear evolution of a rising tone emission generated at the magnetic equator. Using the physical parameters inferred from the wave, particle, and magnetic field data measured by the Cluster spacecraft, we determine the dispersion relation for the EMIC waves. Integrating the differential equations numerically, we obtain a solution for the time variation of the amplitude and frequency of a rising tone emission at the equator. Assuming saturation of the wave amplitude, as is found in the observations, we find good agreement between the numerical solutions and the wave spectrum of the EMIC triggered emissions.

  14. Magnetohydrodynamic Simulations for Studying Solar Flare Trigger Mechanism

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Muhamad, J.; Kusano, K.; Inoue, S.

    In order to understand the flare trigger mechanism, we conduct three-dimensional magnetohydrodynamic simulations using a coronal magnetic field model derived from data observed by the Hinode satellite. Several types of magnetic bipoles are imposed into the photospheric boundary of the Nonlinear Force-free Field model of Active Region (AR) NOAA 10930 on 2006 December 13, to investigate what kind of magnetic disturbance may trigger the flare. As a result, we confirm that certain small bipole fields, which emerge into the highly sheared global magnetic field of an AR, can effectively trigger a flare. These bipole fields can be classified into twomore » groups based on their orientation relative to the polarity inversion line: the so-called opposite polarity, and reversed shear structures, as suggested by Kusano et al. We also investigate the structure of the footpoints of reconnected field lines. By comparing the distribution of reconstructed field lines and observed flare ribbons, the trigger structure of the flare can be inferred. Our simulation suggests that the data-constrained simulation, taking into account both the large-scale magnetic structure and small-scale magnetic disturbance (such as emerging fluxes), is a good way to discover a flare-producing AR, which can be applied to space weather prediction.« less

  15. Development of Overflow-Prevention Valve with Trigger Mechanism.

    NASA Astrophysics Data System (ADS)

    Ishino, Yuji; Mizuno, Takeshi; Takasaki, Masaya

    2016-09-01

    A new overflow-prevention valve for combustible fluid is developed which uses a trigger mechanism. Loading arms for combustible fluid are used for transferring oil from a tanker to tanks and vice versa. The loading arm has a valve for preventing overflow. Overflow- prevention valves cannot use any electric component to avoid combustion. Therefore, the valve must be constructed only by mechanical parts. The conventional overflow-prevention valve uses fluid and pneumatic forces. It consists of a sensor probe, a cylinder, a main valve for shutting off the fluid and a locking mechanism for holding an open state of the main valve. The proposed overflow-prevention valve uses the pressure due to the height difference between the fluid level of the tank and the sensor probe. However, the force of the cylinder produced by the pressure is too small to release the locking mechanism. Therefore, a trigger mechanism is introduced between the cylinder and the locking mechanism. The trigger mechanism produces sufficient force to release the locking mechanism and close the main valve when the height of fluid exceeds a threshold value. A trigger mechanism is designed and fabricated. The operation necessary for closing the main valve is conformed experimentally.

  16. Could Stroke Trigger Be Prevented by Healthy Family Relationships?

    ERIC Educational Resources Information Center

    Rochette, Annie; Gaulin, Philippe; Tellier, Myriam

    2009-01-01

    Although major stroke risk factors are well documented, little is known about which life circumstances are perceived to be related to the actual triggering of a first stroke. The purpose was to explore self-perceived spontaneously related life circumstances surrounding the trigger of a first stroke. A qualitative design with a phenomenological…

  17. Dual-stage periodic event-triggered output-feedback control for linear systems.

    PubMed

    Ruan, Zhen; Chen, Wu-Hua; Lu, Xiaomei

    2018-05-01

    This paper proposes an event-triggered control framework, called dual-stage periodic event-triggered control (DSPETC), which unifies periodic event-triggered control (PETC) and switching event-triggered control (SETC). Specifically, two period parameters h 1 and h 2 are introduced to characterize the new event-triggering rule, where h 1 denotes the sampling period, while h 2 denotes the monitoring period. By choosing some specified values of h 2 , the proposed control scheme can reduce to PETC or SETC scheme. In the DSPETC framework, the controlled system is represented as a switched system model and its stability is analyzed via a switching-time-dependent Lyapunov functional. Both the cases with/without network-induced delays are investigated. Simulation and experimental results show that the DSPETC scheme is superior to the PETC scheme and the SETC scheme. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.

  18. The CMS electron and photon trigger for the LHC Run 2

    NASA Astrophysics Data System (ADS)

    Dezoort, Gage; Xia, Fan

    2017-01-01

    The CMS experiment implements a sophisticated two-level triggering system composed of Level-1, instrumented by custom-design hardware boards, and a software High-Level-Trigger. A new Level-1 trigger architecture with improved performance is now being used to maintain the thresholds that were used in LHC Run I for the more challenging luminosity conditions experienced during Run II. The upgrades to the calorimetry trigger will be described along with performance data. The algorithms for the selection of final states with electrons and photons, both for precision measurements and for searches of new physics beyond the Standard Model, will be described in detail.

  19. Photofrin binds to procaspase-3 and mediates photodynamic treatment-triggered methionine oxidation and inactivation of procaspase-3

    PubMed Central

    Hsieh, Y-J; Chien, K-Y; Lin, S-Y; Sabu, S; Hsu, R-M; Chi, L-M; Lyu, P-C; Yu, J-S

    2012-01-01

    Diverse death phenotypes of cancer cells can be induced by Photofrin-mediated photodynamic therapy (PDT), which has a decisive role in eliciting a tumor-specific immunity for long-term tumor control. However, the mechanism(s) underlying this diversity remain elusive. Caspase-3 is a critical factor in determining cell death phenotypes in many physiological settings. Here, we report that Photofrin-PDT can modify and inactivate procaspase-3 in cancer cells. In cells exposed to an external apoptotic trigger, high-dose Photofrin-PDT pretreatment blocked the proteolytic activation of procaspase-3 by its upstream caspase. We generated and purified recombinant procaspase-3-D3A (a mutant without autolysis/autoactivation activity) to explore the underlying mechanism(s). Photofrin could bind directly to procaspase-3-D3A, and Photofrin-PDT-triggered inactivation and modification of procaspase-3-D3A was seen in vitro. Mass spectrometry-based quantitative analysis for post-translational modifications using both 16O/18O- and 14N/15N-labeling strategies revealed that Photofrin-PDT triggered a significant oxidation of procaspase-3-D3A (mainly on Met-27, -39 and -44) in a Photofrin dose-dependent manner, whereas the active site Cys-163 remained largely unmodified. Site-directed mutagenesis experiments further showed that Met-44 has an important role in procaspase-3 activation. Collectively, our results reveal that Met oxidation is a novel mechanism for the Photofrin-PDT-mediated inactivation of procaspase-3, potentially explaining at least some of the complicated cell death phenotypes triggered by PDT. PMID:22785533

  20. [A novel serial port auto trigger system for MOSFET dose acquisition].

    PubMed

    Luo, Guangwen; Qi, Zhenyu

    2013-01-01

    To synchronize the radiation of microSelectron-HDR (Nucletron afterloading machine) and measurement of MOSFET dose system, a trigger system based on interface circuit was designed and corresponding monitor and trigger program were developed on Qt platform. This interface and control system was tested and showed stable operate and reliable work. This adopted serial port detect technique may expand to trigger application of other medical devices.