Sample records for estimating parameter values

  1. Application of nonlinear least-squares regression to ground-water flow modeling, west-central Florida

    USGS Publications Warehouse

    Yobbi, D.K.

    2000-01-01

    A nonlinear least-squares regression technique for estimation of ground-water flow model parameters was applied to an existing model of the regional aquifer system underlying west-central Florida. The regression technique minimizes the differences between measured and simulated water levels. Regression statistics, including parameter sensitivities and correlations, were calculated for reported parameter values in the existing model. Optimal parameter values for selected hydrologic variables of interest are estimated by nonlinear regression. Optimal estimates of parameter values are about 140 times greater than and about 0.01 times less than reported values. Independently estimating all parameters by nonlinear regression was impossible, given the existing zonation structure and number of observations, because of parameter insensitivity and correlation. Although the model yields parameter values similar to those estimated by other methods and reproduces the measured water levels reasonably accurately, a simpler parameter structure should be considered. Some possible ways of improving model calibration are to: (1) modify the defined parameter-zonation structure by omitting and/or combining parameters to be estimated; (2) carefully eliminate observation data based on evidence that they are likely to be biased; (3) collect additional water-level data; (4) assign values to insensitive parameters, and (5) estimate the most sensitive parameters first, then, using the optimized values for these parameters, estimate the entire data set.

  2. Bayesian Parameter Estimation for Heavy-Duty Vehicles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, Eric; Konan, Arnaud; Duran, Adam

    2017-03-28

    Accurate vehicle parameters are valuable for design, modeling, and reporting. Estimating vehicle parameters can be a very time-consuming process requiring tightly-controlled experimentation. This work describes a method to estimate vehicle parameters such as mass, coefficient of drag/frontal area, and rolling resistance using data logged during standard vehicle operation. The method uses Monte Carlo to generate parameter sets which is fed to a variant of the road load equation. Modeled road load is then compared to measured load to evaluate the probability of the parameter set. Acceptance of a proposed parameter set is determined using the probability ratio to the currentmore » state, so that the chain history will give a distribution of parameter sets. Compared to a single value, a distribution of possible values provides information on the quality of estimates and the range of possible parameter values. The method is demonstrated by estimating dynamometer parameters. Results confirm the method's ability to estimate reasonable parameter sets, and indicates an opportunity to increase the certainty of estimates through careful selection or generation of the test drive cycle.« less

  3. A hybrid optimization approach to the estimation of distributed parameters in two-dimensional confined aquifers

    USGS Publications Warehouse

    Heidari, M.; Ranjithan, S.R.

    1998-01-01

    In using non-linear optimization techniques for estimation of parameters in a distributed ground water model, the initial values of the parameters and prior information about them play important roles. In this paper, the genetic algorithm (GA) is combined with the truncated-Newton search technique to estimate groundwater parameters for a confined steady-state ground water model. Use of prior information about the parameters is shown to be important in estimating correct or near-correct values of parameters on a regional scale. The amount of prior information needed for an accurate solution is estimated by evaluation of the sensitivity of the performance function to the parameters. For the example presented here, it is experimentally demonstrated that only one piece of prior information of the least sensitive parameter is sufficient to arrive at the global or near-global optimum solution. For hydraulic head data with measurement errors, the error in the estimation of parameters increases as the standard deviation of the errors increases. Results from our experiments show that, in general, the accuracy of the estimated parameters depends on the level of noise in the hydraulic head data and the initial values used in the truncated-Newton search technique.In using non-linear optimization techniques for estimation of parameters in a distributed ground water model, the initial values of the parameters and prior information about them play important roles. In this paper, the genetic algorithm (GA) is combined with the truncated-Newton search technique to estimate groundwater parameters for a confined steady-state ground water model. Use of prior information about the parameters is shown to be important in estimating correct or near-correct values of parameters on a regional scale. The amount of prior information needed for an accurate solution is estimated by evaluation of the sensitivity of the performance function to the parameters. For the example presented here, it is experimentally demonstrated that only one piece of prior information of the least sensitive parameter is sufficient to arrive at the global or near-global optimum solution. For hydraulic head data with measurement errors, the error in the estimation of parameters increases as the standard deviation of the errors increases. Results from our experiments show that, in general, the accuracy of the estimated parameters depends on the level of noise in the hydraulic head data and the initial values used in the truncated-Newton search technique.

  4. Ensemble-Based Parameter Estimation in a Coupled GCM Using the Adaptive Spatial Average Method

    DOE PAGES

    Liu, Y.; Liu, Z.; Zhang, S.; ...

    2014-05-29

    Ensemble-based parameter estimation for a climate model is emerging as an important topic in climate research. And for a complex system such as a coupled ocean–atmosphere general circulation model, the sensitivity and response of a model variable to a model parameter could vary spatially and temporally. An adaptive spatial average (ASA) algorithm is proposed to increase the efficiency of parameter estimation. Refined from a previous spatial average method, the ASA uses the ensemble spread as the criterion for selecting “good” values from the spatially varying posterior estimated parameter values; these good values are then averaged to give the final globalmore » uniform posterior parameter. In comparison with existing methods, the ASA parameter estimation has a superior performance: faster convergence and enhanced signal-to-noise ratio.« less

  5. Time Domain Estimation of Arterial Parameters using the Windkessel Model and the Monte Carlo Method

    NASA Astrophysics Data System (ADS)

    Gostuski, Vladimir; Pastore, Ignacio; Rodriguez Palacios, Gaspar; Vaca Diez, Gustavo; Moscoso-Vasquez, H. Marcela; Risk, Marcelo

    2016-04-01

    Numerous parameter estimation techniques exist for characterizing the arterial system using electrical circuit analogs. However, they are often limited by their requirements and usually high computational burdain. Therefore, a new method for estimating arterial parameters based on Monte Carlo simulation is proposed. A three element Windkessel model was used to represent the arterial system. The approach was to reduce the error between the calculated and physiological aortic pressure by randomly generating arterial parameter values, while keeping constant the arterial resistance. This last value was obtained for each subject using the arterial flow, and was a necessary consideration in order to obtain a unique set of values for the arterial compliance and peripheral resistance. The estimation technique was applied to in vivo data containing steady beats in mongrel dogs, and it reliably estimated Windkessel arterial parameters. Further, this method appears to be computationally efficient for on-line time-domain estimation of these parameters.

  6. Contrast-enhanced 3T MR Perfusion of Musculoskeletal Tumours: T1 Value Heterogeneity Assessment and Evaluation of the Influence of T1 Estimation Methods on Quantitative Parameters.

    PubMed

    Gondim Teixeira, Pedro Augusto; Leplat, Christophe; Chen, Bailiang; De Verbizier, Jacques; Beaumont, Marine; Badr, Sammy; Cotten, Anne; Blum, Alain

    2017-12-01

    To evaluate intra-tumour and striated muscle T1 value heterogeneity and the influence of different methods of T1 estimation on the variability of quantitative perfusion parameters. Eighty-two patients with a histologically confirmed musculoskeletal tumour were prospectively included in this study and, with ethics committee approval, underwent contrast-enhanced MR perfusion and T1 mapping. T1 value variations in viable tumour areas and in normal-appearing striated muscle were assessed. In 20 cases, normal muscle perfusion parameters were calculated using three different methods: signal based and gadolinium concentration based on fixed and variable T1 values. Tumour and normal muscle T1 values were significantly different (p = 0.0008). T1 value heterogeneity was higher in tumours than in normal muscle (variation of 19.8% versus 13%). The T1 estimation method had a considerable influence on the variability of perfusion parameters. Fixed T1 values yielded higher coefficients of variation than variable T1 values (mean 109.6 ± 41.8% and 58.3 ± 14.1% respectively). Area under the curve was the least variable parameter (36%). T1 values in musculoskeletal tumours are significantly different and more heterogeneous than normal muscle. Patient-specific T1 estimation is needed for direct inter-patient comparison of perfusion parameters. • T1 value variation in musculoskeletal tumours is considerable. • T1 values in muscle and tumours are significantly different. • Patient-specific T1 estimation is needed for comparison of inter-patient perfusion parameters. • Technical variation is higher in permeability than semiquantitative perfusion parameters.

  7. Modification of a rainfall-runoff model for distributed modeling in a GIS and its validation

    NASA Astrophysics Data System (ADS)

    Nyabeze, W. R.

    A rainfall-runoff model, which can be inter-faced with a Geographical Information System (GIS) to integrate definition, measurement, calculating parameter values for spatial features, presents considerable advantages. The modification of the GWBasic Wits Rainfall-Runoff Erosion Model (GWBRafler) to enable parameter value estimation in a GIS (GISRafler) is presented in this paper. Algorithms are applied to estimate parameter values reducing the number of input parameters and the effort to populate them. The use of a GIS makes the relationship between parameter estimates and cover characteristics more evident. This paper has been produced as part of research to generalize the GWBRafler on a spatially distributed basis. Modular data structures are assumed and parameter values are weighted relative to the module area and centroid properties. Modifications to the GWBRafler enable better estimation of low flows, which are typical in drought conditions.

  8. Application of an automatic approach to calibrate the NEMURO nutrient-phytoplankton-zooplankton food web model in the Oyashio region

    NASA Astrophysics Data System (ADS)

    Ito, Shin-ichi; Yoshie, Naoki; Okunishi, Takeshi; Ono, Tsuneo; Okazaki, Yuji; Kuwata, Akira; Hashioka, Taketo; Rose, Kenneth A.; Megrey, Bernard A.; Kishi, Michio J.; Nakamachi, Miwa; Shimizu, Yugo; Kakehi, Shigeho; Saito, Hiroaki; Takahashi, Kazutaka; Tadokoro, Kazuaki; Kusaka, Akira; Kasai, Hiromi

    2010-10-01

    The Oyashio region in the western North Pacific supports high biological productivity and has been well monitored. We applied the NEMURO (North Pacific Ecosystem Model for Understanding Regional Oceanography) model to simulate the nutrients, phytoplankton, and zooplankton dynamics. Determination of parameters values is very important, yet ad hoc calibration methods are often used. We used the automatic calibration software PEST (model-independent Parameter ESTimation), which has been used previously with NEMURO but in a system without ontogenetic vertical migration of the large zooplankton functional group. Determining the performance of PEST with vertical migration, and obtaining a set of realistic parameter values for the Oyashio, will likely be useful in future applications of NEMURO. Five identical twin simulation experiments were performed with the one-box version of NEMURO. The experiments differed in whether monthly snapshot or averaged state variables were used, in whether state variables were model functional groups or were aggregated (total phytoplankton, small plus large zooplankton), and in whether vertical migration of large zooplankton was included or not. We then applied NEMURO to monthly climatological field data covering 1 year for the Oyashio, and compared model fits and parameter values between PEST-determined estimates and values used in previous applications to the Oyashio region that relied on ad hoc calibration. We substituted the PEST and ad hoc calibrated parameter values into a 3-D version of NEMURO for the western North Pacific, and compared the two sets of spatial maps of chlorophyll- a with satellite-derived data. The identical twin experiments demonstrated that PEST could recover the known model parameter values when vertical migration was included, and that over-fitting can occur as a result of slight differences in the values of the state variables. PEST recovered known parameter values when using monthly snapshots of aggregated state variables, but estimated a different set of parameters with monthly averaged values. Both sets of parameters resulted in good fits of the model to the simulated data. Disaggregating the variables provided to PEST into functional groups did not solve the over-fitting problem, and including vertical migration seemed to amplify the problem. When we used the climatological field data, simulated values with PEST-estimated parameters were closer to these field data than with the previously determined ad hoc set of parameter values. When these same PEST and ad hoc sets of parameter values were substituted into 3-D-NEMURO (without vertical migration), the PEST-estimated parameter values generated spatial maps that were similar to the satellite data for the Kuroshio Extension during January and March and for the subarctic ocean from May to November. With non-linear problems, such as vertical migration, PEST should be used with caution because parameter estimates can be sensitive to how the data are prepared and to the values used for the searching parameters of PEST. We recommend the usage of PEST, or other parameter optimization methods, to generate first-order parameter estimates for simulating specific systems and for insertion into 2-D and 3-D models. The parameter estimates that are generated are useful, and the inconsistencies between simulated values and the available field data provide valuable information on model behavior and the dynamics of the ecosystem.

  9. Estimation of Community Land Model parameters for an improved assessment of net carbon fluxes at European sites

    NASA Astrophysics Data System (ADS)

    Post, Hanna; Vrugt, Jasper A.; Fox, Andrew; Vereecken, Harry; Hendricks Franssen, Harrie-Jan

    2017-03-01

    The Community Land Model (CLM) contains many parameters whose values are uncertain and thus require careful estimation for model application at individual sites. Here we used Bayesian inference with the DiffeRential Evolution Adaptive Metropolis (DREAM(zs)) algorithm to estimate eight CLM v.4.5 ecosystem parameters using 1 year records of half-hourly net ecosystem CO2 exchange (NEE) observations of four central European sites with different plant functional types (PFTs). The posterior CLM parameter distributions of each site were estimated per individual season and on a yearly basis. These estimates were then evaluated using NEE data from an independent evaluation period and data from "nearby" FLUXNET sites at 600 km distance to the original sites. Latent variables (multipliers) were used to treat explicitly uncertainty in the initial carbon-nitrogen pools. The posterior parameter estimates were superior to their default values in their ability to track and explain the measured NEE data of each site. The seasonal parameter values reduced with more than 50% (averaged over all sites) the bias in the simulated NEE values. The most consistent performance of CLM during the evaluation period was found for the posterior parameter values of the forest PFTs, and contrary to the C3-grass and C3-crop sites, the latent variables of the initial pools further enhanced the quality-of-fit. The carbon sink function of the forest PFTs significantly increased with the posterior parameter estimates. We thus conclude that land surface model predictions of carbon stocks and fluxes require careful consideration of uncertain ecological parameters and initial states.

  10. The "covariation method" for estimating the parameters of the standard Dynamic Energy Budget model II: Properties and preliminary patterns

    NASA Astrophysics Data System (ADS)

    Lika, Konstadia; Kearney, Michael R.; Kooijman, Sebastiaan A. L. M.

    2011-11-01

    The covariation method for estimating the parameters of the standard Dynamic Energy Budget (DEB) model provides a single-step method of accessing all the core DEB parameters from commonly available empirical data. In this study, we assess the robustness of this parameter estimation procedure and analyse the role of pseudo-data using elasticity coefficients. In particular, we compare the performance of Maximum Likelihood (ML) vs. Weighted Least Squares (WLS) approaches and find that the two approaches tend to converge in performance as the number of uni-variate data sets increases, but that WLS is more robust when data sets comprise single points (zero-variate data). The efficiency of the approach is shown to be high, and the prior parameter estimates (pseudo-data) have very little influence if the real data contain information about the parameter values. For instance, the effects of the pseudo-value for the allocation fraction κ is reduced when there is information for both growth and reproduction, that for the energy conductance is reduced when information on age at birth and puberty is given, and the effects of the pseudo-value for the maturity maintenance rate coefficient are insignificant. The estimation of some parameters (e.g., the zoom factor and the shape coefficient) requires little information, while that of others (e.g., maturity maintenance rate, puberty threshold and reproduction efficiency) require data at several food levels. The generality of the standard DEB model, in combination with the estimation of all of its parameters, allows comparison of species on the basis of parameter values. We discuss a number of preliminary patterns emerging from the present collection of parameter estimates across a wide variety of taxa. We make the observation that the estimated value of the fraction κ of mobilised reserve that is allocated to soma is far away from the value that maximises reproduction. We recognise this as the reason why two very different parameter sets must exist that fit most data set reasonably well, and give arguments why, in most cases, the set with the large value of κ should be preferred. The continued development of a parameter database through the estimation procedures described here will provide a strong basis for understanding evolutionary patterns in metabolic organisation across the diversity of life.

  11. Determination of stability and control parameters of a light airplane from flight data using two estimation methods. [equation error and maximum likelihood methods

    NASA Technical Reports Server (NTRS)

    Klein, V.

    1979-01-01

    Two identification methods, the equation error method and the output error method, are used to estimate stability and control parameter values from flight data for a low-wing, single-engine, general aviation airplane. The estimated parameters from both methods are in very good agreement primarily because of sufficient accuracy of measured data. The estimated static parameters also agree with the results from steady flights. The effect of power different input forms are demonstrated. Examination of all results available gives the best values of estimated parameters and specifies their accuracies.

  12. Inverse gas chromatographic determination of solubility parameters of excipients.

    PubMed

    Adamska, Katarzyna; Voelkel, Adam

    2005-11-04

    The principle aim of this work was an application of inverse gas chromatography (IGC) for the estimation of solubility parameter for pharmaceutical excipients. The retention data of number of test solutes were used to calculate Flory-Huggins interaction parameter (chi1,2infinity) and than solubility parameter (delta2), corrected solubility parameter (deltaT) and its components (deltad, deltap, deltah) by using different procedures. The influence of different values of test solutes solubility parameter (delta1) over calculated values was estimated. The solubility parameter values obtained for all excipients from the slope, from Guillet and co-workers' procedure are higher than that obtained from components according Voelkel and Janas procedure. It was found that solubility parameter's value of the test solutes influences, but not significantly, values of solubility parameter of excipients.

  13. The estimation of parameter compaction values for pavement subgrade stabilized with lime

    NASA Astrophysics Data System (ADS)

    Lubis, A. S.; Muis, Z. A.; Simbolon, C. A.

    2018-02-01

    The type of soil material, field control, maintenance and availability of funds are several factors that must be considered in compaction of the pavement subgrade. In determining the compaction parameters in laboratory desperately requires considerable materials, time and funds, and reliable laboratory operators. If the result of soil classification values can be used to estimate the compaction parameters of a subgrade material, so it would save time, energy, materials and cost on the execution of this work. This is also a clarification (cross check) of the work that has been done by technicians in the laboratory. The study aims to estimate the compaction parameter values ie. maximum dry unit weight (γdmax) and optimum water content (Wopt) of the soil subgrade that stabilized with lime. The tests that conducted in the laboratory of soil mechanics were to determine the index properties (Fines and Liquid Limit/LL) and Standard Compaction Test. Soil samples that have Plasticity Index (PI) > 10% were made with additional 3% lime for 30 samples. By using the Goswami equation, the compaction parameter values can be estimated by equation γd max # = -0,1686 Log G + 1,8434 and Wopt # = 2,9178 log G + 17,086. From the validation calculation, there was a significant positive correlation between the compaction parameter values laboratory and the compaction parameter values estimated, with a 95% confidence interval as a strong relationship.

  14. Estimation of pharmacokinetic parameters from non-compartmental variables using Microsoft Excel.

    PubMed

    Dansirikul, Chantaratsamon; Choi, Malcolm; Duffull, Stephen B

    2005-06-01

    This study was conducted to develop a method, termed 'back analysis (BA)', for converting non-compartmental variables to compartment model dependent pharmacokinetic parameters for both one- and two-compartment models. A Microsoft Excel spreadsheet was implemented with the use of Solver and visual basic functions. The performance of the BA method in estimating pharmacokinetic parameter values was evaluated by comparing the parameter values obtained to a standard modelling software program, NONMEM, using simulated data. The results show that the BA method was reasonably precise and provided low bias in estimating fixed and random effect parameters for both one- and two-compartment models. The pharmacokinetic parameters estimated from the BA method were similar to those of NONMEM estimation.

  15. Sensitivity of NTCP parameter values against a change of dose calculation algorithm.

    PubMed

    Brink, Carsten; Berg, Martin; Nielsen, Morten

    2007-09-01

    Optimization of radiation treatment planning requires estimations of the normal tissue complication probability (NTCP). A number of models exist that estimate NTCP from a calculated dose distribution. Since different dose calculation algorithms use different approximations the dose distributions predicted for a given treatment will in general depend on the algorithm. The purpose of this work is to test whether the optimal NTCP parameter values change significantly when the dose calculation algorithm is changed. The treatment plans for 17 breast cancer patients have retrospectively been recalculated with a collapsed cone algorithm (CC) to compare the NTCP estimates for radiation pneumonitis with those obtained from the clinically used pencil beam algorithm (PB). For the PB calculations the NTCP parameters were taken from previously published values for three different models. For the CC calculations the parameters were fitted to give the same NTCP as for the PB calculations. This paper demonstrates that significant shifts of the NTCP parameter values are observed for three models, comparable in magnitude to the uncertainties of the published parameter values. Thus, it is important to quote the applied dose calculation algorithm when reporting estimates of NTCP parameters in order to ensure correct use of the models.

  16. Sensitivity of NTCP parameter values against a change of dose calculation algorithm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brink, Carsten; Berg, Martin; Nielsen, Morten

    2007-09-15

    Optimization of radiation treatment planning requires estimations of the normal tissue complication probability (NTCP). A number of models exist that estimate NTCP from a calculated dose distribution. Since different dose calculation algorithms use different approximations the dose distributions predicted for a given treatment will in general depend on the algorithm. The purpose of this work is to test whether the optimal NTCP parameter values change significantly when the dose calculation algorithm is changed. The treatment plans for 17 breast cancer patients have retrospectively been recalculated with a collapsed cone algorithm (CC) to compare the NTCP estimates for radiation pneumonitis withmore » those obtained from the clinically used pencil beam algorithm (PB). For the PB calculations the NTCP parameters were taken from previously published values for three different models. For the CC calculations the parameters were fitted to give the same NTCP as for the PB calculations. This paper demonstrates that significant shifts of the NTCP parameter values are observed for three models, comparable in magnitude to the uncertainties of the published parameter values. Thus, it is important to quote the applied dose calculation algorithm when reporting estimates of NTCP parameters in order to ensure correct use of the models.« less

  17. Two-dimensional advective transport in ground-water flow parameter estimation

    USGS Publications Warehouse

    Anderman, E.R.; Hill, M.C.; Poeter, E.P.

    1996-01-01

    Nonlinear regression is useful in ground-water flow parameter estimation, but problems of parameter insensitivity and correlation often exist given commonly available hydraulic-head and head-dependent flow (for example, stream and lake gain or loss) observations. To address this problem, advective-transport observations are added to the ground-water flow, parameter-estimation model MODFLOWP using particle-tracking methods. The resulting model is used to investigate the importance of advective-transport observations relative to head-dependent flow observations when either or both are used in conjunction with hydraulic-head observations in a simulation of the sewage-discharge plume at Otis Air Force Base, Cape Cod, Massachusetts, USA. The analysis procedure for evaluating the probable effect of new observations on the regression results consists of two steps: (1) parameter sensitivities and correlations calculated at initial parameter values are used to assess the model parameterization and expected relative contributions of different types of observations to the regression; and (2) optimal parameter values are estimated by nonlinear regression and evaluated. In the Cape Cod parameter-estimation model, advective-transport observations did not significantly increase the overall parameter sensitivity; however: (1) inclusion of advective-transport observations decreased parameter correlation enough for more unique parameter values to be estimated by the regression; (2) realistic uncertainties in advective-transport observations had a small effect on parameter estimates relative to the precision with which the parameters were estimated; and (3) the regression results and sensitivity analysis provided insight into the dynamics of the ground-water flow system, especially the importance of accurate boundary conditions. In this work, advective-transport observations improved the calibration of the model and the estimation of ground-water flow parameters, and use of regression and related techniques produced significant insight into the physical system.

  18. Description of the National Hydrologic Model for use with the Precipitation-Runoff Modeling System (PRMS)

    USGS Publications Warehouse

    Regan, R. Steven; Markstrom, Steven L.; Hay, Lauren E.; Viger, Roland J.; Norton, Parker A.; Driscoll, Jessica M.; LaFontaine, Jacob H.

    2018-01-08

    This report documents several components of the U.S. Geological Survey National Hydrologic Model of the conterminous United States for use with the Precipitation-Runoff Modeling System (PRMS). It provides descriptions of the (1) National Hydrologic Model, (2) Geospatial Fabric for National Hydrologic Modeling, (3) PRMS hydrologic simulation code, (4) parameters and estimation methods used to compute spatially and temporally distributed default values as required by PRMS, (5) National Hydrologic Model Parameter Database, and (6) model extraction tool named Bandit. The National Hydrologic Model Parameter Database contains values for all PRMS parameters used in the National Hydrologic Model. The methods and national datasets used to estimate all the PRMS parameters are described. Some parameter values are derived from characteristics of topography, land cover, soils, geology, and hydrography using traditional Geographic Information System methods. Other parameters are set to long-established default values and computation of initial values. Additionally, methods (statistical, sensitivity, calibration, and algebraic) were developed to compute parameter values on the basis of a variety of nationally-consistent datasets. Values in the National Hydrologic Model Parameter Database can periodically be updated on the basis of new parameter estimation methods and as additional national datasets become available. A companion ScienceBase resource provides a set of static parameter values as well as images of spatially-distributed parameters associated with PRMS states and fluxes for each Hydrologic Response Unit across the conterminuous United States.

  19. Extremes in ecology: Avoiding the misleading effects of sampling variation in summary analyses

    USGS Publications Warehouse

    Link, W.A.; Sauer, J.R.

    1996-01-01

    Surveys such as the North American Breeding Bird Survey (BBS) produce large collections of parameter estimates. One's natural inclination when confronted with lists of parameter estimates is to look for the extreme values: in the BBS, these correspond to the species that appear to have the greatest changes in population size through time. Unfortunately, extreme estimates are liable to correspond to the most poorly estimated parameters. Consequently, the most extreme parameters may not match up with the most extreme parameter estimates. The ranking of parameter values on the basis of their estimates are a difficult statistical problem. We use data from the BBS and simulations to illustrate the potential misleading effects of sampling variation in rankings of parameters. We describe empirical Bayes and constrained empirical Bayes procedures which provide partial solutions to the problem of ranking in the presence of sampling variation.

  20. Effects of data structure on the estimation of covariance functions to describe genotype by environment interactions in a reaction norm model

    PubMed Central

    Calus, Mario PL; Bijma, Piter; Veerkamp, Roel F

    2004-01-01

    Covariance functions have been proposed to predict breeding values and genetic (co)variances as a function of phenotypic within herd-year averages (environmental parameters) to include genotype by environment interaction. The objective of this paper was to investigate the influence of definition of environmental parameters and non-random use of sires on expected breeding values and estimated genetic variances across environments. Breeding values were simulated as a linear function of simulated herd effects. The definition of environmental parameters hardly influenced the results. In situations with random use of sires, estimated genetic correlations between the trait expressed in different environments were 0.93, 0.93 and 0.97 while simulated at 0.89 and estimated genetic variances deviated up to 30% from the simulated values. Non random use of sires, poor genetic connectedness and small herd size had a large impact on the estimated covariance functions, expected breeding values and calculated environmental parameters. Estimated genetic correlations between a trait expressed in different environments were biased upwards and breeding values were more biased when genetic connectedness became poorer and herd composition more diverse. The best possible solution at this stage is to use environmental parameters combining large numbers of animals per herd, while losing some information on genotype by environment interaction in the data. PMID:15339629

  1. 40 CFR 98.35 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... Procedures for estimating missing data. Whenever a quality-assured value of a required parameter is... substitute data value for the missing parameter shall be used in the calculations. (a) For all units subject...

  2. 40 CFR 98.35 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... Procedures for estimating missing data. Whenever a quality-assured value of a required parameter is... substitute data value for the missing parameter shall be used in the calculations. (a) For all units subject...

  3. 40 CFR 98.35 - Procedures for estimating missing data.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Procedures for estimating missing data... Procedures for estimating missing data. Whenever a quality-assured value of a required parameter is... substitute data value for the missing parameter shall be used in the calculations. (a) For all units subject...

  4. 40 CFR 98.35 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... Procedures for estimating missing data. Whenever a quality-assured value of a required parameter is... substitute data value for the missing parameter shall be used in the calculations. (a) For all units subject...

  5. 40 CFR 98.35 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... Procedures for estimating missing data. Whenever a quality-assured value of a required parameter is... substitute data value for the missing parameter shall be used in the calculations. (a) For all units subject...

  6. 40 CFR 98.295 - Procedures for estimating missing data.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... value shall be the best available estimate(s) of the parameter(s), based on all available process data or data used for accounting purposes. (c) For each missing value collected during the performance test (hourly CO2 concentration, stack gas volumetric flow rate, or average process vent flow from mine...

  7. An improved state-parameter analysis of ecosystem models using data assimilation

    USGS Publications Warehouse

    Chen, M.; Liu, S.; Tieszen, L.L.; Hollinger, D.Y.

    2008-01-01

    Much of the effort spent in developing data assimilation methods for carbon dynamics analysis has focused on estimating optimal values for either model parameters or state variables. The main weakness of estimating parameter values alone (i.e., without considering state variables) is that all errors from input, output, and model structure are attributed to model parameter uncertainties. On the other hand, the accuracy of estimating state variables may be lowered if the temporal evolution of parameter values is not incorporated. This research develops a smoothed ensemble Kalman filter (SEnKF) by combining ensemble Kalman filter with kernel smoothing technique. SEnKF has following characteristics: (1) to estimate simultaneously the model states and parameters through concatenating unknown parameters and state variables into a joint state vector; (2) to mitigate dramatic, sudden changes of parameter values in parameter sampling and parameter evolution process, and control narrowing of parameter variance which results in filter divergence through adjusting smoothing factor in kernel smoothing algorithm; (3) to assimilate recursively data into the model and thus detect possible time variation of parameters; and (4) to address properly various sources of uncertainties stemming from input, output and parameter uncertainties. The SEnKF is tested by assimilating observed fluxes of carbon dioxide and environmental driving factor data from an AmeriFlux forest station located near Howland, Maine, USA, into a partition eddy flux model. Our analysis demonstrates that model parameters, such as light use efficiency, respiration coefficients, minimum and optimum temperatures for photosynthetic activity, and others, are highly constrained by eddy flux data at daily-to-seasonal time scales. The SEnKF stabilizes parameter values quickly regardless of the initial values of the parameters. Potential ecosystem light use efficiency demonstrates a strong seasonality. Results show that the simultaneous parameter estimation procedure significantly improves model predictions. Results also show that the SEnKF can dramatically reduce the variance in state variables stemming from the uncertainty of parameters and driving variables. The SEnKF is a robust and effective algorithm in evaluating and developing ecosystem models and in improving the understanding and quantification of carbon cycle parameters and processes. ?? 2008 Elsevier B.V.

  8. Optimized tuner selection for engine performance estimation

    NASA Technical Reports Server (NTRS)

    Simon, Donald L. (Inventor); Garg, Sanjay (Inventor)

    2013-01-01

    A methodology for minimizing the error in on-line Kalman filter-based aircraft engine performance estimation applications is presented. This technique specifically addresses the underdetermined estimation problem, where there are more unknown parameters than available sensor measurements. A systematic approach is applied to produce a model tuning parameter vector of appropriate dimension to enable estimation by a Kalman filter, while minimizing the estimation error in the parameters of interest. Tuning parameter selection is performed using a multi-variable iterative search routine which seeks to minimize the theoretical mean-squared estimation error. Theoretical Kalman filter estimation error bias and variance values are derived at steady-state operating conditions, and the tuner selection routine is applied to minimize these values. The new methodology yields an improvement in on-line engine performance estimation accuracy.

  9. Ballistic projectile trajectory determining system

    DOEpatents

    Karr, Thomas J.

    1997-01-01

    A computer controlled system determines the three-dimensional trajectory of a ballistic projectile. To initialize the system, predictions of state parameters for a ballistic projectile are received at an estimator. The estimator uses the predictions of the state parameters to estimate first trajectory characteristics of the ballistic projectile. A single stationary monocular sensor then observes the actual first trajectory characteristics of the ballistic projectile. A comparator generates an error value related to the predicted state parameters by comparing the estimated first trajectory characteristics of the ballistic projectile with the observed first trajectory characteristics of the ballistic projectile. If the error value is equal to or greater than a selected limit, the predictions of the state parameters are adjusted. New estimates for the trajectory characteristics of the ballistic projectile are made and are then compared with actual observed trajectory characteristics. This process is repeated until the error value is less than the selected limit. Once the error value is less than the selected limit, a calculator calculates trajectory characteristics such a the origin and destination of the ballistic projectile.

  10. A framework for streamflow prediction in the world's most severely data-limited regions: Test of applicability and performance in a poorly-gauged region of China

    NASA Astrophysics Data System (ADS)

    Alipour, M. H.; Kibler, Kelly M.

    2018-02-01

    A framework methodology is proposed for streamflow prediction in poorly-gauged rivers located within large-scale regions of sparse hydrometeorologic observation. A multi-criteria model evaluation is developed to select models that balance runoff efficiency with selection of accurate parameter values. Sparse observed data are supplemented by uncertain or low-resolution information, incorporated as 'soft' data, to estimate parameter values a priori. Model performance is tested in two catchments within a data-poor region of southwestern China, and results are compared to models selected using alternative calibration methods. While all models perform consistently with respect to runoff efficiency (NSE range of 0.67-0.78), models selected using the proposed multi-objective method may incorporate more representative parameter values than those selected by traditional calibration. Notably, parameter values estimated by the proposed method resonate with direct estimates of catchment subsurface storage capacity (parameter residuals of 20 and 61 mm for maximum soil moisture capacity (Cmax), and 0.91 and 0.48 for soil moisture distribution shape factor (B); where a parameter residual is equal to the centroid of a soft parameter value minus the calibrated parameter value). A model more traditionally calibrated to observed data only (single-objective model) estimates a much lower soil moisture capacity (residuals of Cmax = 475 and 518 mm and B = 1.24 and 0.7). A constrained single-objective model also underestimates maximum soil moisture capacity relative to a priori estimates (residuals of Cmax = 246 and 289 mm). The proposed method may allow managers to more confidently transfer calibrated models to ungauged catchments for streamflow predictions, even in the world's most data-limited regions.

  11. New fast least-squares algorithm for estimating the best-fitting parameters due to simple geometric-structures from gravity anomalies.

    PubMed

    Essa, Khalid S

    2014-01-01

    A new fast least-squares method is developed to estimate the shape factor (q-parameter) of a buried structure using normalized residual anomalies obtained from gravity data. The problem of shape factor estimation is transformed into a problem of finding a solution of a non-linear equation of the form f(q) = 0 by defining the anomaly value at the origin and at different points on the profile (N-value). Procedures are also formulated to estimate the depth (z-parameter) and the amplitude coefficient (A-parameter) of the buried structure. The method is simple and rapid for estimating parameters that produced gravity anomalies. This technique is used for a class of geometrically simple anomalous bodies, including the semi-infinite vertical cylinder, the infinitely long horizontal cylinder, and the sphere. The technique is tested and verified on theoretical models with and without random errors. It is also successfully applied to real data sets from Senegal and India, and the inverted-parameters are in good agreement with the known actual values.

  12. New fast least-squares algorithm for estimating the best-fitting parameters due to simple geometric-structures from gravity anomalies

    PubMed Central

    Essa, Khalid S.

    2013-01-01

    A new fast least-squares method is developed to estimate the shape factor (q-parameter) of a buried structure using normalized residual anomalies obtained from gravity data. The problem of shape factor estimation is transformed into a problem of finding a solution of a non-linear equation of the form f(q) = 0 by defining the anomaly value at the origin and at different points on the profile (N-value). Procedures are also formulated to estimate the depth (z-parameter) and the amplitude coefficient (A-parameter) of the buried structure. The method is simple and rapid for estimating parameters that produced gravity anomalies. This technique is used for a class of geometrically simple anomalous bodies, including the semi-infinite vertical cylinder, the infinitely long horizontal cylinder, and the sphere. The technique is tested and verified on theoretical models with and without random errors. It is also successfully applied to real data sets from Senegal and India, and the inverted-parameters are in good agreement with the known actual values. PMID:25685472

  13. Quantifying model-structure- and parameter-driven uncertainties in spring wheat phenology prediction with Bayesian analysis

    DOE PAGES

    Alderman, Phillip D.; Stanfill, Bryan

    2016-10-06

    Recent international efforts have brought renewed emphasis on the comparison of different agricultural systems models. Thus far, analysis of model-ensemble simulated results has not clearly differentiated between ensemble prediction uncertainties due to model structural differences per se and those due to parameter value uncertainties. Additionally, despite increasing use of Bayesian parameter estimation approaches with field-scale crop models, inadequate attention has been given to the full posterior distributions for estimated parameters. The objectives of this study were to quantify the impact of parameter value uncertainty on prediction uncertainty for modeling spring wheat phenology using Bayesian analysis and to assess the relativemore » contributions of model-structure-driven and parameter-value-driven uncertainty to overall prediction uncertainty. This study used a random walk Metropolis algorithm to estimate parameters for 30 spring wheat genotypes using nine phenology models based on multi-location trial data for days to heading and days to maturity. Across all cases, parameter-driven uncertainty accounted for between 19 and 52% of predictive uncertainty, while model-structure-driven uncertainty accounted for between 12 and 64%. Here, this study demonstrated the importance of quantifying both model-structure- and parameter-value-driven uncertainty when assessing overall prediction uncertainty in modeling spring wheat phenology. More generally, Bayesian parameter estimation provided a useful framework for quantifying and analyzing sources of prediction uncertainty.« less

  14. Sample Size and Item Parameter Estimation Precision When Utilizing the One-Parameter "Rasch" Model

    ERIC Educational Resources Information Center

    Custer, Michael

    2015-01-01

    This study examines the relationship between sample size and item parameter estimation precision when utilizing the one-parameter model. Item parameter estimates are examined relative to "true" values by evaluating the decline in root mean squared deviation (RMSD) and the number of outliers as sample size increases. This occurs across…

  15. Parameter estimation of multivariate multiple regression model using bayesian with non-informative Jeffreys’ prior distribution

    NASA Astrophysics Data System (ADS)

    Saputro, D. R. S.; Amalia, F.; Widyaningsih, P.; Affan, R. C.

    2018-05-01

    Bayesian method is a method that can be used to estimate the parameters of multivariate multiple regression model. Bayesian method has two distributions, there are prior and posterior distributions. Posterior distribution is influenced by the selection of prior distribution. Jeffreys’ prior distribution is a kind of Non-informative prior distribution. This prior is used when the information about parameter not available. Non-informative Jeffreys’ prior distribution is combined with the sample information resulting the posterior distribution. Posterior distribution is used to estimate the parameter. The purposes of this research is to estimate the parameters of multivariate regression model using Bayesian method with Non-informative Jeffreys’ prior distribution. Based on the results and discussion, parameter estimation of β and Σ which were obtained from expected value of random variable of marginal posterior distribution function. The marginal posterior distributions for β and Σ are multivariate normal and inverse Wishart. However, in calculation of the expected value involving integral of a function which difficult to determine the value. Therefore, approach is needed by generating of random samples according to the posterior distribution characteristics of each parameter using Markov chain Monte Carlo (MCMC) Gibbs sampling algorithm.

  16. Improved Estimates of Thermodynamic Parameters

    NASA Technical Reports Server (NTRS)

    Lawson, D. D.

    1982-01-01

    Techniques refined for estimating heat of vaporization and other parameters from molecular structure. Using parabolic equation with three adjustable parameters, heat of vaporization can be used to estimate boiling point, and vice versa. Boiling points and vapor pressures for some nonpolar liquids were estimated by improved method and compared with previously reported values. Technique for estimating thermodynamic parameters should make it easier for engineers to choose among candidate heat-exchange fluids for thermochemical cycles.

  17. Ballistic projectile trajectory determining system

    DOEpatents

    Karr, T.J.

    1997-05-20

    A computer controlled system determines the three-dimensional trajectory of a ballistic projectile. To initialize the system, predictions of state parameters for a ballistic projectile are received at an estimator. The estimator uses the predictions of the state parameters to estimate first trajectory characteristics of the ballistic projectile. A single stationary monocular sensor then observes the actual first trajectory characteristics of the ballistic projectile. A comparator generates an error value related to the predicted state parameters by comparing the estimated first trajectory characteristics of the ballistic projectile with the observed first trajectory characteristics of the ballistic projectile. If the error value is equal to or greater than a selected limit, the predictions of the state parameters are adjusted. New estimates for the trajectory characteristics of the ballistic projectile are made and are then compared with actual observed trajectory characteristics. This process is repeated until the error value is less than the selected limit. Once the error value is less than the selected limit, a calculator calculates trajectory characteristics such a the origin and destination of the ballistic projectile. 8 figs.

  18. Spatially constrained incoherent motion method improves diffusion-weighted MRI signal decay analysis in the liver and spleen

    PubMed Central

    Taimouri, Vahid; Afacan, Onur; Perez-Rossello, Jeannette M.; Callahan, Michael J.; Mulkern, Robert V.; Warfield, Simon K.; Freiman, Moti

    2015-01-01

    Purpose: To evaluate the effect of the spatially constrained incoherent motion (SCIM) method on improving the precision and robustness of fast and slow diffusion parameter estimates from diffusion-weighted MRI in liver and spleen in comparison to the independent voxel-wise intravoxel incoherent motion (IVIM) model. Methods: We collected diffusion-weighted MRI (DW-MRI) data of 29 subjects (5 healthy subjects and 24 patients with Crohn’s disease in the ileum). We evaluated parameters estimates’ robustness against different combinations of b-values (i.e., 4 b-values and 7 b-values) by comparing the variance of the estimates obtained with the SCIM and the independent voxel-wise IVIM model. We also evaluated the improvement in the precision of parameter estimates by comparing the coefficient of variation (CV) of the SCIM parameter estimates to that of the IVIM. Results: The SCIM method was more robust compared to IVIM (up to 70% in liver and spleen) for different combinations of b-values. Also, the CV values of the parameter estimations using the SCIM method were significantly lower compared to repeated acquisition and signal averaging estimated using IVIM, especially for the fast diffusion parameter in liver (CVIV IM = 46.61 ± 11.22, CVSCIM = 16.85 ± 2.160, p < 0.001) and spleen (CVIV IM = 95.15 ± 19.82, CVSCIM = 52.55 ± 1.91, p < 0.001). Conclusions: The SCIM method characterizes fast and slow diffusion more precisely compared to the independent voxel-wise IVIM model fitting in the liver and spleen. PMID:25832079

  19. Models for estimating photosynthesis parameters from in situ production profiles

    NASA Astrophysics Data System (ADS)

    Kovač, Žarko; Platt, Trevor; Sathyendranath, Shubha; Antunović, Suzana

    2017-12-01

    The rate of carbon assimilation in phytoplankton primary production models is mathematically prescribed with photosynthesis irradiance functions, which convert a light flux (energy) into a material flux (carbon). Information on this rate is contained in photosynthesis parameters: the initial slope and the assimilation number. The exactness of parameter values is crucial for precise calculation of primary production. Here we use a model of the daily production profile based on a suite of photosynthesis irradiance functions and extract photosynthesis parameters from in situ measured daily production profiles at the Hawaii Ocean Time-series station Aloha. For each function we recover parameter values, establish parameter distributions and quantify model skill. We observe that the choice of the photosynthesis irradiance function to estimate the photosynthesis parameters affects the magnitudes of parameter values as recovered from in situ profiles. We also tackle the problem of parameter exchange amongst the models and the effect it has on model performance. All models displayed little or no bias prior to parameter exchange, but significant bias following parameter exchange. The best model performance resulted from using optimal parameter values. Model formulation was extended further by accounting for spectral effects and deriving a spectral analytical solution for the daily production profile. The daily production profile was also formulated with time dependent growing biomass governed by a growth equation. The work on parameter recovery was further extended by exploring how to extract photosynthesis parameters from information on watercolumn production. It was demonstrated how to estimate parameter values based on a linearization of the full analytical solution for normalized watercolumn production and from the solution itself, without linearization. The paper complements previous works on photosynthesis irradiance models by analysing the skill and consistency of photosynthesis irradiance functions and parameters for modeling in situ production profiles. In light of the results obtained in this work we argue that the choice of the primary production model should reflect the available data and these models should be data driven regarding parameter estimation.

  20. Uncertainties in the Item Parameter Estimates and Robust Automated Test Assembly

    ERIC Educational Resources Information Center

    Veldkamp, Bernard P.; Matteucci, Mariagiulia; de Jong, Martijn G.

    2013-01-01

    Item response theory parameters have to be estimated, and because of the estimation process, they do have uncertainty in them. In most large-scale testing programs, the parameters are stored in item banks, and automated test assembly algorithms are applied to assemble operational test forms. These algorithms treat item parameters as fixed values,…

  1. Examining the Feasibility and Utility of Estimating Partial Expected Value of Perfect Information (via a Nonparametric Approach) as Part of the Reimbursement Decision-Making Process in Ireland: Application to Drugs for Cancer.

    PubMed

    McCullagh, Laura; Schmitz, Susanne; Barry, Michael; Walsh, Cathal

    2017-11-01

    In Ireland, all new drugs for which reimbursement by the healthcare payer is sought undergo a health technology assessment by the National Centre for Pharmacoeconomics. The National Centre for Pharmacoeconomics estimate expected value of perfect information but not partial expected value of perfect information (owing to computational expense associated with typical methodologies). The objective of this study was to examine the feasibility and utility of estimating partial expected value of perfect information via a computationally efficient, non-parametric regression approach. This was a retrospective analysis of evaluations on drugs for cancer that had been submitted to the National Centre for Pharmacoeconomics (January 2010 to December 2014 inclusive). Drugs were excluded if cost effective at the submitted price. Drugs were excluded if concerns existed regarding the validity of the applicants' submission or if cost-effectiveness model functionality did not allow required modifications to be made. For each included drug (n = 14), value of information was estimated at the final reimbursement price, at a threshold equivalent to the incremental cost-effectiveness ratio at that price. The expected value of perfect information was estimated from probabilistic analysis. Partial expected value of perfect information was estimated via a non-parametric approach. Input parameters with a population value at least €1 million were identified as potential targets for research. All partial estimates were determined within minutes. Thirty parameters (across nine models) each had a value of at least €1 million. These were categorised. Collectively, survival analysis parameters were valued at €19.32 million, health state utility parameters at €15.81 million and parameters associated with the cost of treating adverse effects at €6.64 million. Those associated with drug acquisition costs and with the cost of care were valued at €6.51 million and €5.71 million, respectively. This research demonstrates that the estimation of partial expected value of perfect information via this computationally inexpensive approach could be considered feasible as part of the health technology assessment process for reimbursement purposes within the Irish healthcare system. It might be a useful tool in prioritising future research to decrease decision uncertainty.

  2. Attitude determination and parameter estimation using vector observations - Theory

    NASA Technical Reports Server (NTRS)

    Markley, F. Landis

    1989-01-01

    Procedures for attitude determination based on Wahba's loss function are generalized to include the estimation of parameters other than the attitude, such as sensor biases. Optimization with respect to the attitude is carried out using the q-method, which does not require an a priori estimate of the attitude. Optimization with respect to the other parameters employs an iterative approach, which does require an a priori estimate of these parameters. Conventional state estimation methods require a priori estimates of both the parameters and the attitude, while the algorithm presented in this paper always computes the exact optimal attitude for given values of the parameters. Expressions for the covariance of the attitude and parameter estimates are derived.

  3. Standard Errors of Estimated Latent Variable Scores with Estimated Structural Parameters

    ERIC Educational Resources Information Center

    Hoshino, Takahiro; Shigemasu, Kazuo

    2008-01-01

    The authors propose a concise formula to evaluate the standard error of the estimated latent variable score when the true values of the structural parameters are not known and must be estimated. The formula can be applied to factor scores in factor analysis or ability parameters in item response theory, without bootstrap or Markov chain Monte…

  4. Development of genetic algorithm-based optimization module in WHAT system for hydrograph analysis and model application

    NASA Astrophysics Data System (ADS)

    Lim, Kyoung Jae; Park, Youn Shik; Kim, Jonggun; Shin, Yong-Chul; Kim, Nam Won; Kim, Seong Joon; Jeon, Ji-Hong; Engel, Bernard A.

    2010-07-01

    Many hydrologic and water quality computer models have been developed and applied to assess hydrologic and water quality impacts of land use changes. These models are typically calibrated and validated prior to their application. The Long-Term Hydrologic Impact Assessment (L-THIA) model was applied to the Little Eagle Creek (LEC) watershed and compared with the filtered direct runoff using BFLOW and the Eckhardt digital filter (with a default BFI max value of 0.80 and filter parameter value of 0.98), both available in the Web GIS-based Hydrograph Analysis Tool, called WHAT. The R2 value and the Nash-Sutcliffe coefficient values were 0.68 and 0.64 with BFLOW, and 0.66 and 0.63 with the Eckhardt digital filter. Although these results indicate that the L-THIA model estimates direct runoff reasonably well, the filtered direct runoff values using BFLOW and Eckhardt digital filter with the default BFI max and filter parameter values do not reflect hydrological and hydrogeological situations in the LEC watershed. Thus, a BFI max GA-Analyzer module (BFI max Genetic Algorithm-Analyzer module) was developed and integrated into the WHAT system for determination of the optimum BFI max parameter and filter parameter of the Eckhardt digital filter. With the automated recession curve analysis method and BFI max GA-Analyzer module of the WHAT system, the optimum BFI max value of 0.491 and filter parameter value of 0.987 were determined for the LEC watershed. The comparison of L-THIA estimates with filtered direct runoff using an optimized BFI max and filter parameter resulted in an R2 value of 0.66 and the Nash-Sutcliffe coefficient value of 0.63. However, L-THIA estimates calibrated with the optimized BFI max and filter parameter increased by 33% and estimated NPS pollutant loadings increased by more than 20%. This indicates L-THIA model direct runoff estimates can be incorrect by 33% and NPS pollutant loading estimation by more than 20%, if the accuracy of the baseflow separation method is not validated for the study watershed prior to model comparison. This study shows the importance of baseflow separation in hydrologic and water quality modeling using the L-THIA model.

  5. K-ε Turbulence Model Parameter Estimates Using an Approximate Self-similar Jet-in-Crossflow Solution

    DOE PAGES

    DeChant, Lawrence; Ray, Jaideep; Lefantzi, Sophia; ...

    2017-06-09

    The k-ε turbulence model has been described as perhaps “the most widely used complete turbulence model.” This family of heuristic Reynolds Averaged Navier-Stokes (RANS) turbulence closures is supported by a suite of model parameters that have been estimated by demanding the satisfaction of well-established canonical flows such as homogeneous shear flow, log-law behavior, etc. While this procedure does yield a set of so-called nominal parameters, it is abundantly clear that they do not provide a universally satisfactory turbulence model that is capable of simulating complex flows. Recent work on the Bayesian calibration of the k-ε model using jet-in-crossflow wind tunnelmore » data has yielded parameter estimates that are far more predictive than nominal parameter values. In this paper, we develop a self-similar asymptotic solution for axisymmetric jet-in-crossflow interactions and derive analytical estimates of the parameters that were inferred using Bayesian calibration. The self-similar method utilizes a near field approach to estimate the turbulence model parameters while retaining the classical far-field scaling to model flow field quantities. Our parameter values are seen to be far more predictive than the nominal values, as checked using RANS simulations and experimental measurements. They are also closer to the Bayesian estimates than the nominal parameters. A traditional simplified jet trajectory model is explicitly related to the turbulence model parameters and is shown to yield good agreement with measurement when utilizing the analytical derived turbulence model coefficients. Finally, the close agreement between the turbulence model coefficients obtained via Bayesian calibration and the analytically estimated coefficients derived in this paper is consistent with the contention that the Bayesian calibration approach is firmly rooted in the underlying physical description.« less

  6. State and parameter estimation of the heat shock response system using Kalman and particle filters.

    PubMed

    Liu, Xin; Niranjan, Mahesan

    2012-06-01

    Traditional models of systems biology describe dynamic biological phenomena as solutions to ordinary differential equations, which, when parameters in them are set to correct values, faithfully mimic observations. Often parameter values are tweaked by hand until desired results are achieved, or computed from biochemical experiments carried out in vitro. Of interest in this article, is the use of probabilistic modelling tools with which parameters and unobserved variables, modelled as hidden states, can be estimated from limited noisy observations of parts of a dynamical system. Here we focus on sequential filtering methods and take a detailed look at the capabilities of three members of this family: (i) extended Kalman filter (EKF), (ii) unscented Kalman filter (UKF) and (iii) the particle filter, in estimating parameters and unobserved states of cellular response to sudden temperature elevation of the bacterium Escherichia coli. While previous literature has studied this system with the EKF, we show that parameter estimation is only possible with this method when the initial guesses are sufficiently close to the true values. The same turns out to be true for the UKF. In this thorough empirical exploration, we show that the non-parametric method of particle filtering is able to reliably estimate parameters and states, converging from initial distributions relatively far away from the underlying true values. Software implementation of the three filters on this problem can be freely downloaded from http://users.ecs.soton.ac.uk/mn/HeatShock

  7. Designing occupancy studies when false-positive detections occur

    USGS Publications Warehouse

    Clement, Matthew

    2016-01-01

    1.Recently, estimators have been developed to estimate occupancy probabilities when false-positive detections occur during presence-absence surveys. Some of these estimators combine different types of survey data to improve estimates of occupancy. With these estimators, there is a tradeoff between the number of sample units surveyed, and the number and type of surveys at each sample unit. Guidance on efficient design of studies when false positives occur is unavailable. 2.For a range of scenarios, I identified survey designs that minimized the mean square error of the estimate of occupancy. I considered an approach that uses one survey method and two observation states and an approach that uses two survey methods. For each approach, I used numerical methods to identify optimal survey designs when model assumptions were met and parameter values were correctly anticipated, when parameter values were not correctly anticipated, and when the assumption of no unmodelled detection heterogeneity was violated. 3.Under the approach with two observation states, false positive detections increased the number of recommended surveys, relative to standard occupancy models. If parameter values could not be anticipated, pessimism about detection probabilities avoided poor designs. Detection heterogeneity could require more or fewer repeat surveys, depending on parameter values. If model assumptions were met, the approach with two survey methods was inefficient. However, with poor anticipation of parameter values, with detection heterogeneity, or with removal sampling schemes, combining two survey methods could improve estimates of occupancy. 4.Ignoring false positives can yield biased parameter estimates, yet false positives greatly complicate the design of occupancy studies. Specific guidance for major types of false-positive occupancy models, and for two assumption violations common in field data, can conserve survey resources. This guidance can be used to design efficient monitoring programs and studies of species occurrence, species distribution, or habitat selection, when false positives occur during surveys.

  8. Estimating hydraulic parameters of a heterogeneous aquitard using long-term multi-extensometer and groundwater level data

    NASA Astrophysics Data System (ADS)

    Zhuang, Chao; Zhou, Zhifang; Illman, Walter A.; Guo, Qiaona; Wang, Jinguo

    2017-09-01

    The classical aquitard-drainage model COMPAC has been modified to simulate the compaction process of a heterogeneous aquitard consisting of multiple sub-units (Multi-COMPAC). By coupling Multi-COMPAC with the parameter estimation code PEST++, the vertical hydraulic conductivity ( K v) and elastic ( S ske) and inelastic ( S skp) skeletal specific-storage values of each sub-unit can be estimated using observed long-term multi-extensometer and groundwater level data. The approach was first tested through a synthetic case with known parameters. Results of the synthetic case revealed that it was possible to accurately estimate the three parameters for each sub-unit. Next, the methodology was applied to a field site located in Changzhou city, China. Based on the detailed stratigraphic information and extensometer data, the aquitard of interest was subdivided into three sub-units. Parameters K v, S ske and S skp of each sub-unit were estimated simultaneously and then were compared with laboratory results and with bulk values and geologic data from previous studies, demonstrating the reliability of parameter estimates. Estimated S skp values ranged within the magnitude of 10-4 m-1, while K v ranged over 10-10-10-8 m/s, suggesting moderately high heterogeneity of the aquitard. However, the elastic deformation of the third sub-unit, consisting of soft plastic silty clay, is masked by delayed drainage, and the inverse procedure leads to large uncertainty in the S ske estimate for this sub-unit.

  9. Simultaneous versus sequential optimal experiment design for the identification of multi-parameter microbial growth kinetics as a function of temperature.

    PubMed

    Van Derlinden, E; Bernaerts, K; Van Impe, J F

    2010-05-21

    Optimal experiment design for parameter estimation (OED/PE) has become a popular tool for efficient and accurate estimation of kinetic model parameters. When the kinetic model under study encloses multiple parameters, different optimization strategies can be constructed. The most straightforward approach is to estimate all parameters simultaneously from one optimal experiment (single OED/PE strategy). However, due to the complexity of the optimization problem or the stringent limitations on the system's dynamics, the experimental information can be limited and parameter estimation convergence problems can arise. As an alternative, we propose to reduce the optimization problem to a series of two-parameter estimation problems, i.e., an optimal experiment is designed for a combination of two parameters while presuming the other parameters known. Two different approaches can be followed: (i) all two-parameter optimal experiments are designed based on identical initial parameter estimates and parameters are estimated simultaneously from all resulting experimental data (global OED/PE strategy), and (ii) optimal experiments are calculated and implemented sequentially whereby the parameter values are updated intermediately (sequential OED/PE strategy). This work exploits OED/PE for the identification of the Cardinal Temperature Model with Inflection (CTMI) (Rosso et al., 1993). This kinetic model describes the effect of temperature on the microbial growth rate and encloses four parameters. The three OED/PE strategies are considered and the impact of the OED/PE design strategy on the accuracy of the CTMI parameter estimation is evaluated. Based on a simulation study, it is observed that the parameter values derived from the sequential approach deviate more from the true parameters than the single and global strategy estimates. The single and global OED/PE strategies are further compared based on experimental data obtained from design implementation in a bioreactor. Comparable estimates are obtained, but global OED/PE estimates are, in general, more accurate and reliable. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  10. Estimation of Filling and Afterload Conditions by Pump Intrinsic Parameters in a Pulsatile Total Artificial Heart.

    PubMed

    Cuenca-Navalon, Elena; Laumen, Marco; Finocchiaro, Thomas; Steinseifer, Ulrich

    2016-07-01

    A physiological control algorithm is being developed to ensure an optimal physiological interaction between the ReinHeart total artificial heart (TAH) and the circulatory system. A key factor for that is the long-term, accurate determination of the hemodynamic state of the cardiovascular system. This study presents a method to determine estimation models for predicting hemodynamic parameters (pump chamber filling and afterload) from both left and right cardiovascular circulations. The estimation models are based on linear regression models that correlate filling and afterload values with pump intrinsic parameters derived from measured values of motor current and piston position. Predictions for filling lie in average within 5% from actual values, predictions for systemic afterload (AoPmean , AoPsys ) and mean pulmonary afterload (PAPmean ) lie in average within 9% from actual values. Predictions for systolic pulmonary afterload (PAPsys ) present an average deviation of 14%. The estimation models show satisfactory prediction and confidence intervals and are thus suitable to estimate hemodynamic parameters. This method and derived estimation models are a valuable alternative to implanted sensors and are an essential step for the development of a physiological control algorithm for a fully implantable TAH. Copyright © 2015 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

  11. On the applicability of surrogate-based Markov chain Monte Carlo-Bayesian inversion to the Community Land Model: Case studies at flux tower sites: SURROGATE-BASED MCMC FOR CLM

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, Maoyi; Ray, Jaideep; Hou, Zhangshuan

    2016-07-04

    The Community Land Model (CLM) has been widely used in climate and Earth system modeling. Accurate estimation of model parameters is needed for reliable model simulations and predictions under current and future conditions, respectively. In our previous work, a subset of hydrological parameters has been identified to have significant impact on surface energy fluxes at selected flux tower sites based on parameter screening and sensitivity analysis, which indicate that the parameters could potentially be estimated from surface flux observations at the towers. To date, such estimates do not exist. In this paper, we assess the feasibility of applying a Bayesianmore » model calibration technique to estimate CLM parameters at selected flux tower sites under various site conditions. The parameters are estimated as a joint probability density function (PDF) that provides estimates of uncertainty of the parameters being inverted, conditional on climatologically-average latent heat fluxes derived from observations. We find that the simulated mean latent heat fluxes from CLM using the calibrated parameters are generally improved at all sites when compared to those obtained with CLM simulations using default parameter sets. Further, our calibration method also results in credibility bounds around the simulated mean fluxes which bracket the measured data. The modes (or maximum a posteriori values) and 95% credibility intervals of the site-specific posterior PDFs are tabulated as suggested parameter values for each site. Analysis of relationships between the posterior PDFs and site conditions suggests that the parameter values are likely correlated with the plant functional type, which needs to be confirmed in future studies by extending the approach to more sites.« less

  12. On the applicability of surrogate-based MCMC-Bayesian inversion to the Community Land Model: Case studies at Flux tower sites

    DOE PAGES

    Huang, Maoyi; Ray, Jaideep; Hou, Zhangshuan; ...

    2016-06-01

    The Community Land Model (CLM) has been widely used in climate and Earth system modeling. Accurate estimation of model parameters is needed for reliable model simulations and predictions under current and future conditions, respectively. In our previous work, a subset of hydrological parameters has been identified to have significant impact on surface energy fluxes at selected flux tower sites based on parameter screening and sensitivity analysis, which indicate that the parameters could potentially be estimated from surface flux observations at the towers. To date, such estimates do not exist. In this paper, we assess the feasibility of applying a Bayesianmore » model calibration technique to estimate CLM parameters at selected flux tower sites under various site conditions. The parameters are estimated as a joint probability density function (PDF) that provides estimates of uncertainty of the parameters being inverted, conditional on climatologically average latent heat fluxes derived from observations. We find that the simulated mean latent heat fluxes from CLM using the calibrated parameters are generally improved at all sites when compared to those obtained with CLM simulations using default parameter sets. Further, our calibration method also results in credibility bounds around the simulated mean fluxes which bracket the measured data. The modes (or maximum a posteriori values) and 95% credibility intervals of the site-specific posterior PDFs are tabulated as suggested parameter values for each site. As a result, analysis of relationships between the posterior PDFs and site conditions suggests that the parameter values are likely correlated with the plant functional type, which needs to be confirmed in future studies by extending the approach to more sites.« less

  13. On the applicability of surrogate-based MCMC-Bayesian inversion to the Community Land Model: Case studies at Flux tower sites

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, Maoyi; Ray, Jaideep; Hou, Zhangshuan

    The Community Land Model (CLM) has been widely used in climate and Earth system modeling. Accurate estimation of model parameters is needed for reliable model simulations and predictions under current and future conditions, respectively. In our previous work, a subset of hydrological parameters has been identified to have significant impact on surface energy fluxes at selected flux tower sites based on parameter screening and sensitivity analysis, which indicate that the parameters could potentially be estimated from surface flux observations at the towers. To date, such estimates do not exist. In this paper, we assess the feasibility of applying a Bayesianmore » model calibration technique to estimate CLM parameters at selected flux tower sites under various site conditions. The parameters are estimated as a joint probability density function (PDF) that provides estimates of uncertainty of the parameters being inverted, conditional on climatologically average latent heat fluxes derived from observations. We find that the simulated mean latent heat fluxes from CLM using the calibrated parameters are generally improved at all sites when compared to those obtained with CLM simulations using default parameter sets. Further, our calibration method also results in credibility bounds around the simulated mean fluxes which bracket the measured data. The modes (or maximum a posteriori values) and 95% credibility intervals of the site-specific posterior PDFs are tabulated as suggested parameter values for each site. As a result, analysis of relationships between the posterior PDFs and site conditions suggests that the parameter values are likely correlated with the plant functional type, which needs to be confirmed in future studies by extending the approach to more sites.« less

  14. On the applicability of surrogate-based Markov chain Monte Carlo-Bayesian inversion to the Community Land Model: Case studies at flux tower sites

    NASA Astrophysics Data System (ADS)

    Huang, Maoyi; Ray, Jaideep; Hou, Zhangshuan; Ren, Huiying; Liu, Ying; Swiler, Laura

    2016-07-01

    The Community Land Model (CLM) has been widely used in climate and Earth system modeling. Accurate estimation of model parameters is needed for reliable model simulations and predictions under current and future conditions, respectively. In our previous work, a subset of hydrological parameters has been identified to have significant impact on surface energy fluxes at selected flux tower sites based on parameter screening and sensitivity analysis, which indicate that the parameters could potentially be estimated from surface flux observations at the towers. To date, such estimates do not exist. In this paper, we assess the feasibility of applying a Bayesian model calibration technique to estimate CLM parameters at selected flux tower sites under various site conditions. The parameters are estimated as a joint probability density function (PDF) that provides estimates of uncertainty of the parameters being inverted, conditional on climatologically average latent heat fluxes derived from observations. We find that the simulated mean latent heat fluxes from CLM using the calibrated parameters are generally improved at all sites when compared to those obtained with CLM simulations using default parameter sets. Further, our calibration method also results in credibility bounds around the simulated mean fluxes which bracket the measured data. The modes (or maximum a posteriori values) and 95% credibility intervals of the site-specific posterior PDFs are tabulated as suggested parameter values for each site. Analysis of relationships between the posterior PDFs and site conditions suggests that the parameter values are likely correlated with the plant functional type, which needs to be confirmed in future studies by extending the approach to more sites.

  15. Monaural room acoustic parameters from music and speech.

    PubMed

    Kendrick, Paul; Cox, Trevor J; Li, Francis F; Zhang, Yonggang; Chambers, Jonathon A

    2008-07-01

    This paper compares two methods for extracting room acoustic parameters from reverberated speech and music. An approach which uses statistical machine learning, previously developed for speech, is extended to work with music. For speech, reverberation time estimations are within a perceptual difference limen of the true value. For music, virtually all early decay time estimations are within a difference limen of the true value. The estimation accuracy is not good enough in other cases due to differences between the simulated data set used to develop the empirical model and real rooms. The second method carries out a maximum likelihood estimation on decay phases at the end of notes or speech utterances. This paper extends the method to estimate parameters relating to the balance of early and late energies in the impulse response. For reverberation time and speech, the method provides estimations which are within the perceptual difference limen of the true value. For other parameters such as clarity, the estimations are not sufficiently accurate due to the natural reverberance of the excitation signals. Speech is a better test signal than music because of the greater periods of silence in the signal, although music is needed for low frequency measurement.

  16. Adaptive estimation of nonlinear parameters of a nonholonomic spherical robot using a modified fuzzy-based speed gradient algorithm

    NASA Astrophysics Data System (ADS)

    Roozegar, Mehdi; Mahjoob, Mohammad J.; Ayati, Moosa

    2017-05-01

    This paper deals with adaptive estimation of the unknown parameters and states of a pendulum-driven spherical robot (PDSR), which is a nonlinear in parameters (NLP) chaotic system with parametric uncertainties. Firstly, the mathematical model of the robot is deduced by applying the Newton-Euler methodology for a system of rigid bodies. Then, based on the speed gradient (SG) algorithm, the states and unknown parameters of the robot are estimated online for different step length gains and initial conditions. The estimated parameters are updated adaptively according to the error between estimated and true state values. Since the errors of the estimated states and parameters as well as the convergence rates depend significantly on the value of step length gain, this gain should be chosen optimally. Hence, a heuristic fuzzy logic controller is employed to adjust the gain adaptively. Simulation results indicate that the proposed approach is highly encouraging for identification of this NLP chaotic system even if the initial conditions change and the uncertainties increase; therefore, it is reliable to be implemented on a real robot.

  17. Estimating parameter values of a socio-hydrological flood model

    NASA Astrophysics Data System (ADS)

    Holkje Barendrecht, Marlies; Viglione, Alberto; Kreibich, Heidi; Vorogushyn, Sergiy; Merz, Bruno; Blöschl, Günter

    2018-06-01

    Socio-hydrological modelling studies that have been published so far show that dynamic coupled human-flood models are a promising tool to represent the phenomena and the feedbacks in human-flood systems. So far these models are mostly generic and have not been developed and calibrated to represent specific case studies. We believe that applying and calibrating these type of models to real world case studies can help us to further develop our understanding about the phenomena that occur in these systems. In this paper we propose a method to estimate the parameter values of a socio-hydrological model and we test it by applying it to an artificial case study. We postulate a model that describes the feedbacks between floods, awareness and preparedness. After simulating hypothetical time series with a given combination of parameters, we sample few data points for our variables and try to estimate the parameters given these data points using Bayesian Inference. The results show that, if we are able to collect data for our case study, we would, in theory, be able to estimate the parameter values for our socio-hydrological flood model.

  18. Impacts of different types of measurements on estimating unsaturated flow parameters

    NASA Astrophysics Data System (ADS)

    Shi, Liangsheng; Song, Xuehang; Tong, Juxiu; Zhu, Yan; Zhang, Qiuru

    2015-05-01

    This paper assesses the value of different types of measurements for estimating soil hydraulic parameters. A numerical method based on ensemble Kalman filter (EnKF) is presented to solely or jointly assimilate point-scale soil water head data, point-scale soil water content data, surface soil water content data and groundwater level data. This study investigates the performance of EnKF under different types of data, the potential worth contained in these data, and the factors that may affect estimation accuracy. Results show that for all types of data, smaller measurements errors lead to faster convergence to the true values. Higher accuracy measurements are required to improve the parameter estimation if a large number of unknown parameters need to be identified simultaneously. The data worth implied by the surface soil water content data and groundwater level data is prone to corruption by a deviated initial guess. Surface soil moisture data are capable of identifying soil hydraulic parameters for the top layers, but exert less or no influence on deeper layers especially when estimating multiple parameters simultaneously. Groundwater level is one type of valuable information to infer the soil hydraulic parameters. However, based on the approach used in this study, the estimates from groundwater level data may suffer severe degradation if a large number of parameters must be identified. Combined use of two or more types of data is helpful to improve the parameter estimation.

  19. Impacts of Different Types of Measurements on Estimating Unsaturatedflow Parameters

    NASA Astrophysics Data System (ADS)

    Shi, L.

    2015-12-01

    This study evaluates the value of different types of measurements for estimating soil hydraulic parameters. A numerical method based on ensemble Kalman filter (EnKF) is presented to solely or jointly assimilate point-scale soil water head data, point-scale soil water content data, surface soil water content data and groundwater level data. This study investigates the performance of EnKF under different types of data, the potential worth contained in these data, and the factors that may affect estimation accuracy. Results show that for all types of data, smaller measurements errors lead to faster convergence to the true values. Higher accuracy measurements are required to improve the parameter estimation if a large number of unknown parameters need to be identified simultaneously. The data worth implied by the surface soil water content data and groundwater level data is prone to corruption by a deviated initial guess. Surface soil moisture data are capable of identifying soil hydraulic parameters for the top layers, but exert less or no influence on deeper layers especially when estimating multiple parameters simultaneously. Groundwater level is one type of valuable information to infer the soil hydraulic parameters. However, based on the approach used in this study, the estimates from groundwater level data may suffer severe degradation if a large number of parameters must be identified. Combined use of two or more types of data is helpful to improve the parameter estimation.

  20. Accuracy Estimation and Parameter Advising for Protein Multiple Sequence Alignment

    PubMed Central

    DeBlasio, Dan

    2013-01-01

    Abstract We develop a novel and general approach to estimating the accuracy of multiple sequence alignments without knowledge of a reference alignment, and use our approach to address a new task that we call parameter advising: the problem of choosing values for alignment scoring function parameters from a given set of choices to maximize the accuracy of a computed alignment. For protein alignments, we consider twelve independent features that contribute to a quality alignment. An accuracy estimator is learned that is a polynomial function of these features; its coefficients are determined by minimizing its error with respect to true accuracy using mathematical optimization. Compared to prior approaches for estimating accuracy, our new approach (a) introduces novel feature functions that measure nonlocal properties of an alignment yet are fast to evaluate, (b) considers more general classes of estimators beyond linear combinations of features, and (c) develops new regression formulations for learning an estimator from examples; in addition, for parameter advising, we (d) determine the optimal parameter set of a given cardinality, which specifies the best parameter values from which to choose. Our estimator, which we call Facet (for “feature-based accuracy estimator”), yields a parameter advisor that on the hardest benchmarks provides more than a 27% improvement in accuracy over the best default parameter choice, and for parameter advising significantly outperforms the best prior approaches to assessing alignment quality. PMID:23489379

  1. New procedure for the determination of Hansen solubility parameters by means of inverse gas chromatography.

    PubMed

    Adamska, K; Bellinghausen, R; Voelkel, A

    2008-06-27

    The Hansen solubility parameter (HSP) seems to be a useful tool for the thermodynamic characterization of different materials. Unfortunately, estimation of the HSP values can cause some problems. In this work different procedures by using inverse gas chromatography have been presented for calculation of pharmaceutical excipients' solubility parameter. The new procedure proposed, based on the Lindvig et al. methodology, where experimental data of Flory-Huggins interaction parameter are used, can be a reasonable alternative for the estimation of HSP values. The advantage of this method is that the values of Flory-Huggins interaction parameter chi for all test solutes are used for further calculation, thus diverse interactions between test solute and material are taken into consideration.

  2. Summary of longitudinal stability and control parameters as determined from Space Shuttle Challenger flight test data

    NASA Technical Reports Server (NTRS)

    Suit, William T.

    1989-01-01

    Estimates of longitudinal stability and control parameters for the space shuttle were determined by applying a maximum likelihood parameter estimation technique to Challenger flight test data. The parameters for pitching moment coefficient, C(m sub alpha), (at different angles of attack), pitching moment coefficient, C(m sub delta e), (at different elevator deflections) and the normal force coefficient, C(z sub alpha), (at different angles of attack) describe 90 percent of the response to longitudinal inputs during Space Shuttle Challenger flights with C(m sub delta e) being the dominant parameter. The values of C(z sub alpha) were found to be input dependent for these tests. However, when C(z sub alpha) was set at preflight predictions, the values determined for C(m sub delta e) changed less than 10 percent from the values obtained when C(z sub alpha) was estimated as well. The preflight predictions for C(z sub alpha) and C(m sub alpha) are acceptable values, while the values of C(z sub delta e) should be about 30 percent less negative than the preflight predictions near Mach 1, and 10 percent less negative, otherwise.

  3. Parameter estimation of Monod model by the Least-Squares method for microalgae Botryococcus Braunii sp

    NASA Astrophysics Data System (ADS)

    See, J. J.; Jamaian, S. S.; Salleh, R. M.; Nor, M. E.; Aman, F.

    2018-04-01

    This research aims to estimate the parameters of Monod model of microalgae Botryococcus Braunii sp growth by the Least-Squares method. Monod equation is a non-linear equation which can be transformed into a linear equation form and it is solved by implementing the Least-Squares linear regression method. Meanwhile, Gauss-Newton method is an alternative method to solve the non-linear Least-Squares problem with the aim to obtain the parameters value of Monod model by minimizing the sum of square error ( SSE). As the result, the parameters of the Monod model for microalgae Botryococcus Braunii sp can be estimated by the Least-Squares method. However, the estimated parameters value obtained by the non-linear Least-Squares method are more accurate compared to the linear Least-Squares method since the SSE of the non-linear Least-Squares method is less than the linear Least-Squares method.

  4. A modified Leslie-Gower predator-prey interaction model and parameter identifiability

    NASA Astrophysics Data System (ADS)

    Tripathi, Jai Prakash; Meghwani, Suraj S.; Thakur, Manoj; Abbas, Syed

    2018-01-01

    In this work, bifurcation and a systematic approach for estimation of identifiable parameters of a modified Leslie-Gower predator-prey system with Crowley-Martin functional response and prey refuge is discussed. Global asymptotic stability is discussed by applying fluctuation lemma. The system undergoes into Hopf bifurcation with respect to parameters intrinsic growth rate of predators (s) and prey reserve (m). The stability of Hopf bifurcation is also discussed by calculating Lyapunov number. The sensitivity analysis of the considered model system with respect to all variables is performed which also supports our theoretical study. To estimate the unknown parameter from the data, an optimization procedure (pseudo-random search algorithm) is adopted. System responses and phase plots for estimated parameters are also compared with true noise free data. It is found that the system dynamics with true set of parametric values is similar to the estimated parametric values. Numerical simulations are presented to substantiate the analytical findings.

  5. Space-dependent perfusion coefficient estimation in a 2D bioheat transfer problem

    NASA Astrophysics Data System (ADS)

    Bazán, Fermín S. V.; Bedin, Luciano; Borges, Leonardo S.

    2017-05-01

    In this work, a method for estimating the space-dependent perfusion coefficient parameter in a 2D bioheat transfer model is presented. In the method, the bioheat transfer model is transformed into a time-dependent semidiscrete system of ordinary differential equations involving perfusion coefficient values as parameters, and the estimation problem is solved through a nonlinear least squares technique. In particular, the bioheat problem is solved by the method of lines based on a highly accurate pseudospectral approach, and perfusion coefficient values are estimated by the regularized Gauss-Newton method coupled with a proper regularization parameter. The performance of the method on several test problems is illustrated numerically.

  6. A new method of differential structural analysis of gamma-family basic parameters

    NASA Technical Reports Server (NTRS)

    Melkumian, L. G.; Ter-Antonian, S. V.; Smorodin, Y. A.

    1985-01-01

    The maximum likelihood method is used for the first time to restore parameters of electron photon cascades registered on X-ray films. The method permits one to carry out a structural analysis of the gamma quanta family darkening spots independent of the gamma quanta overlapping degree, and to obtain maximum admissible accuracies in estimating the energies of the gamma quanta composing a family. The parameter estimation accuracy weakly depends on the value of the parameters themselves and exceeds by an order of the values obtained by integral methods.

  7. Net thrust calculation sensitivity of an afterburning turbofan engine to variations in input parameters

    NASA Technical Reports Server (NTRS)

    Hughes, D. L.; Ray, R. J.; Walton, J. T.

    1985-01-01

    The calculated value of net thrust of an aircraft powered by a General Electric F404-GE-400 afterburning turbofan engine was evaluated for its sensitivity to various input parameters. The effects of a 1.0-percent change in each input parameter on the calculated value of net thrust with two calculation methods are compared. This paper presents the results of these comparisons and also gives the estimated accuracy of the overall net thrust calculation as determined from the influence coefficients and estimated parameter measurement accuracies.

  8. Principles of parametric estimation in modeling language competition

    PubMed Central

    Zhang, Menghan; Gong, Tao

    2013-01-01

    It is generally difficult to define reasonable parameters and interpret their values in mathematical models of social phenomena. Rather than directly fitting abstract parameters against empirical data, we should define some concrete parameters to denote the sociocultural factors relevant for particular phenomena, and compute the values of these parameters based upon the corresponding empirical data. Taking the example of modeling studies of language competition, we propose a language diffusion principle and two language inheritance principles to compute two critical parameters, namely the impacts and inheritance rates of competing languages, in our language competition model derived from the Lotka–Volterra competition model in evolutionary biology. These principles assign explicit sociolinguistic meanings to those parameters and calculate their values from the relevant data of population censuses and language surveys. Using four examples of language competition, we illustrate that our language competition model with thus-estimated parameter values can reliably replicate and predict the dynamics of language competition, and it is especially useful in cases lacking direct competition data. PMID:23716678

  9. Principles of parametric estimation in modeling language competition.

    PubMed

    Zhang, Menghan; Gong, Tao

    2013-06-11

    It is generally difficult to define reasonable parameters and interpret their values in mathematical models of social phenomena. Rather than directly fitting abstract parameters against empirical data, we should define some concrete parameters to denote the sociocultural factors relevant for particular phenomena, and compute the values of these parameters based upon the corresponding empirical data. Taking the example of modeling studies of language competition, we propose a language diffusion principle and two language inheritance principles to compute two critical parameters, namely the impacts and inheritance rates of competing languages, in our language competition model derived from the Lotka-Volterra competition model in evolutionary biology. These principles assign explicit sociolinguistic meanings to those parameters and calculate their values from the relevant data of population censuses and language surveys. Using four examples of language competition, we illustrate that our language competition model with thus-estimated parameter values can reliably replicate and predict the dynamics of language competition, and it is especially useful in cases lacking direct competition data.

  10. Estimation of the Parameters in a Two-State System Coupled to a Squeezed Bath

    NASA Astrophysics Data System (ADS)

    Hu, Yao-Hua; Yang, Hai-Feng; Tan, Yong-Gang; Tao, Ya-Ping

    2018-04-01

    Estimation of the phase and weight parameters of a two-state system in a squeezed bath by calculating quantum Fisher information is investigated. The results show that, both for the phase estimation and for the weight estimation, the quantum Fisher information always decays with time and changes periodically with the phases. The estimation precision can be enhanced by choosing the proper values of the phases and the squeezing parameter. These results can be provided as an analysis reference for the practical application of the parameter estimation in a squeezed bath.

  11. The alfa and beta of tumours: a review of parameters of the linear-quadratic model, derived from clinical radiotherapy studies.

    PubMed

    van Leeuwen, C M; Oei, A L; Crezee, J; Bel, A; Franken, N A P; Stalpers, L J A; Kok, H P

    2018-05-16

    Prediction of radiobiological response is a major challenge in radiotherapy. Of several radiobiological models, the linear-quadratic (LQ) model has been best validated by experimental and clinical data. Clinically, the LQ model is mainly used to estimate equivalent radiotherapy schedules (e.g. calculate the equivalent dose in 2 Gy fractions, EQD 2 ), but increasingly also to predict tumour control probability (TCP) and normal tissue complication probability (NTCP) using logistic models. The selection of accurate LQ parameters α, β and α/β is pivotal for a reliable estimate of radiation response. The aim of this review is to provide an overview of published values for the LQ parameters of human tumours as a guideline for radiation oncologists and radiation researchers to select appropriate radiobiological parameter values for LQ modelling in clinical radiotherapy. We performed a systematic literature search and found sixty-four clinical studies reporting α, β and α/β for tumours. Tumour site, histology, stage, number of patients, type of LQ model, radiation type, TCP model, clinical endpoint and radiobiological parameter estimates were extracted. Next, we stratified by tumour site and by tumour histology. Study heterogeneity was expressed by the I 2 statistic, i.e. the percentage of variance in reported values not explained by chance. A large heterogeneity in LQ parameters was found within and between studies (I 2  > 75%). For the same tumour site, differences in histology partially explain differences in the LQ parameters: epithelial tumours have higher α/β values than adenocarcinomas. For tumour sites with different histologies, such as in oesophageal cancer, the α/β estimates correlate well with histology. However, many other factors contribute to the study heterogeneity of LQ parameters, e.g. tumour stage, type of LQ model, TCP model and clinical endpoint (i.e. survival, tumour control and biochemical control). The value of LQ parameters for tumours as published in clinical radiotherapy studies depends on many clinical and methodological factors. Therefore, for clinical use of the LQ model, LQ parameters for tumour should be selected carefully, based on tumour site, histology and the applied LQ model. To account for uncertainties in LQ parameter estimates, exploring a range of values is recommended.

  12. Parameter Estimation of Partial Differential Equation Models.

    PubMed

    Xun, Xiaolei; Cao, Jiguo; Mallick, Bani; Carroll, Raymond J; Maity, Arnab

    2013-01-01

    Partial differential equation (PDE) models are commonly used to model complex dynamic systems in applied sciences such as biology and finance. The forms of these PDE models are usually proposed by experts based on their prior knowledge and understanding of the dynamic system. Parameters in PDE models often have interesting scientific interpretations, but their values are often unknown, and need to be estimated from the measurements of the dynamic system in the present of measurement errors. Most PDEs used in practice have no analytic solutions, and can only be solved with numerical methods. Currently, methods for estimating PDE parameters require repeatedly solving PDEs numerically under thousands of candidate parameter values, and thus the computational load is high. In this article, we propose two methods to estimate parameters in PDE models: a parameter cascading method and a Bayesian approach. In both methods, the underlying dynamic process modeled with the PDE model is represented via basis function expansion. For the parameter cascading method, we develop two nested levels of optimization to estimate the PDE parameters. For the Bayesian method, we develop a joint model for data and the PDE, and develop a novel hierarchical model allowing us to employ Markov chain Monte Carlo (MCMC) techniques to make posterior inference. Simulation studies show that the Bayesian method and parameter cascading method are comparable, and both outperform other available methods in terms of estimation accuracy. The two methods are demonstrated by estimating parameters in a PDE model from LIDAR data.

  13. Approaches to highly parameterized inversion: Pilot-point theory, guidelines, and research directions

    USGS Publications Warehouse

    Doherty, John E.; Fienen, Michael N.; Hunt, Randall J.

    2011-01-01

    Pilot points have been used in geophysics and hydrogeology for at least 30 years as a means to bridge the gap between estimating a parameter value in every cell of a model and subdividing models into a small number of homogeneous zones. Pilot points serve as surrogate parameters at which values are estimated in the inverse-modeling process, and their values are interpolated onto the modeling domain in such a way that heterogeneity can be represented at a much lower computational cost than trying to estimate parameters in every cell of a model. Although the use of pilot points is increasingly common, there are few works documenting the mathematical implications of their use and even fewer sources of guidelines for their implementation in hydrogeologic modeling studies. This report describes the mathematics of pilot-point use, provides guidelines for their use in the parameter-estimation software suite (PEST), and outlines several research directions. Two key attributes for pilot-point definitions are highlighted. First, the difference between the information contained in the every-cell parameter field and the surrogate parameter field created using pilot points should be in the realm of parameters which are not informed by the observed data (the null space). Second, the interpolation scheme for projecting pilot-point values onto model cells ideally should be orthogonal. These attributes are informed by the mathematics and have important ramifications for both the guidelines and suggestions for future research.

  14. A computer-based matrix for rapid calculation of pulmonary hemodynamic parameters in congenital heart disease

    PubMed Central

    Lopes, Antonio Augusto; dos Anjos Miranda, Rogério; Gonçalves, Rilvani Cavalcante; Thomaz, Ana Maria

    2009-01-01

    BACKGROUND: In patients with congenital heart disease undergoing cardiac catheterization for hemodynamic purposes, parameter estimation by the indirect Fick method using a single predicted value of oxygen consumption has been a matter of criticism. OBJECTIVE: We developed a computer-based routine for rapid estimation of replicate hemodynamic parameters using multiple predicted values of oxygen consumption. MATERIALS AND METHODS: Using Microsoft® Excel facilities, we constructed a matrix containing 5 models (equations) for prediction of oxygen consumption, and all additional formulas needed to obtain replicate estimates of hemodynamic parameters. RESULTS: By entering data from 65 patients with ventricular septal defects, aged 1 month to 8 years, it was possible to obtain multiple predictions for oxygen consumption, with clear between-age groups (P <.001) and between-methods (P <.001) differences. Using these predictions in the individual patient, it was possible to obtain the upper and lower limits of a likely range for any given parameter, which made estimation more realistic. CONCLUSION: The organized matrix allows for rapid obtainment of replicate parameter estimates, without error due to exhaustive calculations. PMID:19641642

  15. State and Parameter Estimation for a Coupled Ocean--Atmosphere Model

    NASA Astrophysics Data System (ADS)

    Ghil, M.; Kondrashov, D.; Sun, C.

    2006-12-01

    The El-Nino/Southern-Oscillation (ENSO) dominates interannual climate variability and plays, therefore, a key role in seasonal-to-interannual prediction. Much is known by now about the main physical mechanisms that give rise to and modulate ENSO, but the values of several parameters that enter these mechanisms are an important unknown. We apply Extended Kalman Filtering (EKF) for both model state and parameter estimation in an intermediate, nonlinear, coupled ocean--atmosphere model of ENSO. The coupled model consists of an upper-ocean, reduced-gravity model of the Tropical Pacific and a steady-state atmospheric response to the sea surface temperature (SST). The model errors are assumed to be mainly in the atmospheric wind stress, and assimilated data are equatorial Pacific SSTs. Model behavior is very sensitive to two key parameters: (i) μ, the ocean-atmosphere coupling coefficient between SST and wind stress anomalies; and (ii) δs, the surface-layer coefficient. Previous work has shown that δs determines the period of the model's self-sustained oscillation, while μ measures the degree of nonlinearity. Depending on the values of these parameters, the spatio-temporal pattern of model solutions is either that of a delayed oscillator or of a westward propagating mode. Estimation of these parameters is tested first on synthetic data and allows us to recover the delayed-oscillator mode starting from model parameter values that correspond to the westward-propagating case. Assimilation of SST data from the NCEP-NCAR Reanalysis-2 shows that the parameters can vary on fairly short time scales and switch between values that approximate the two distinct modes of ENSO behavior. Rapid adjustments of these parameters occur, in particular, during strong ENSO events. Ways to apply EKF parameter estimation efficiently to state-of-the-art coupled ocean--atmosphere GCMs will be discussed.

  16. Robust Diagnosis Method Based on Parameter Estimation for an Interturn Short-Circuit Fault in Multipole PMSM under High-Speed Operation.

    PubMed

    Lee, Jewon; Moon, Seokbae; Jeong, Hyeyun; Kim, Sang Woo

    2015-11-20

    This paper proposes a diagnosis method for a multipole permanent magnet synchronous motor (PMSM) under an interturn short circuit fault. Previous works in this area have suffered from the uncertainties of the PMSM parameters, which can lead to misdiagnosis. The proposed method estimates the q-axis inductance (Lq) of the faulty PMSM to solve this problem. The proposed method also estimates the faulty phase and the value of G, which serves as an index of the severity of the fault. The q-axis current is used to estimate the faulty phase, the values of G and Lq. For this reason, two open-loop observers and an optimization method based on a particle-swarm are implemented. The q-axis current of a healthy PMSM is estimated by the open-loop observer with the parameters of a healthy PMSM. The Lq estimation significantly compensates for the estimation errors in high-speed operation. The experimental results demonstrate that the proposed method can estimate the faulty phase, G, and Lq besides exhibiting robustness against parameter uncertainties.

  17. Optimal Tuner Selection for Kalman Filter-Based Aircraft Engine Performance Estimation

    NASA Technical Reports Server (NTRS)

    Simon, Donald L.; Garg, Sanjay

    2010-01-01

    A linear point design methodology for minimizing the error in on-line Kalman filter-based aircraft engine performance estimation applications is presented. This technique specifically addresses the underdetermined estimation problem, where there are more unknown parameters than available sensor measurements. A systematic approach is applied to produce a model tuning parameter vector of appropriate dimension to enable estimation by a Kalman filter, while minimizing the estimation error in the parameters of interest. Tuning parameter selection is performed using a multi-variable iterative search routine which seeks to minimize the theoretical mean-squared estimation error. This paper derives theoretical Kalman filter estimation error bias and variance values at steady-state operating conditions, and presents the tuner selection routine applied to minimize these values. Results from the application of the technique to an aircraft engine simulation are presented and compared to the conventional approach of tuner selection. Experimental simulation results are found to be in agreement with theoretical predictions. The new methodology is shown to yield a significant improvement in on-line engine performance estimation accuracy

  18. Detecting influential observations in nonlinear regression modeling of groundwater flow

    USGS Publications Warehouse

    Yager, Richard M.

    1998-01-01

    Nonlinear regression is used to estimate optimal parameter values in models of groundwater flow to ensure that differences between predicted and observed heads and flows do not result from nonoptimal parameter values. Parameter estimates can be affected, however, by observations that disproportionately influence the regression, such as outliers that exert undue leverage on the objective function. Certain statistics developed for linear regression can be used to detect influential observations in nonlinear regression if the models are approximately linear. This paper discusses the application of Cook's D, which measures the effect of omitting a single observation on a set of estimated parameter values, and the statistical parameter DFBETAS, which quantifies the influence of an observation on each parameter. The influence statistics were used to (1) identify the influential observations in the calibration of a three-dimensional, groundwater flow model of a fractured-rock aquifer through nonlinear regression, and (2) quantify the effect of omitting influential observations on the set of estimated parameter values. Comparison of the spatial distribution of Cook's D with plots of model sensitivity shows that influential observations correspond to areas where the model heads are most sensitive to certain parameters, and where predicted groundwater flow rates are largest. Five of the six discharge observations were identified as influential, indicating that reliable measurements of groundwater flow rates are valuable data in model calibration. DFBETAS are computed and examined for an alternative model of the aquifer system to identify a parameterization error in the model design that resulted in overestimation of the effect of anisotropy on horizontal hydraulic conductivity.

  19. Quantifying thermohaline circulations: seawater isotopic compositions and salinity as proxies of the ratio between advection time and evaporation time

    NASA Astrophysics Data System (ADS)

    Paldor, N.; Berman, H.; Lazar, B.

    2017-12-01

    Uncertainties in quantitative estimates of the thermohaline circulation in any particular basin are large, partly due to large uncertainties in quantifying excess evaporation over precipitation and surface velocities. A single nondimensional parameter, γ=(qx)/(hu) is proposed to characterize the "strength" of the thermohaline circulation by combining the physical parameters of surface velocity (u), evaporation rate (q), mixed layer depth (h) and trajectory length (x). Values of g can be estimated directly from cross-sections of salinity or seawater isotopic composition (δ18O and δD). Estimates of q in the Red Sea and the South-West Indian Ocean are 0.1 and 0.02, respectively, which implies that the thermohaline contribution to the circulation in the former is higher than in the latter. Once the value of g has been determined in a particular basin, either q or u can be estimated from known values of the remaining parameters. In the studied basins such estimates are consistent with previous studies.

  20. System and method for motor parameter estimation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Luhrs, Bin; Yan, Ting

    2014-03-18

    A system and method for determining unknown values of certain motor parameters includes a motor input device connectable to an electric motor having associated therewith values for known motor parameters and an unknown value of at least one motor parameter. The motor input device includes a processing unit that receives a first input from the electric motor comprising values for the known motor parameters for the electric motor and receive a second input comprising motor data on a plurality of reference motors, including values for motor parameters corresponding to the known motor parameters of the electric motor and values formore » motor parameters corresponding to the at least one unknown motor parameter value of the electric motor. The processor determines the unknown value of the at least one motor parameter from the first input and the second input and determines a motor management strategy for the electric motor based thereon.« less

  1. Application of a parameter-estimation technique to modeling the regional aquifer underlying the eastern Snake River plain, Idaho

    USGS Publications Warehouse

    Garabedian, Stephen P.

    1986-01-01

    A nonlinear, least-squares regression technique for the estimation of ground-water flow model parameters was applied to the regional aquifer underlying the eastern Snake River Plain, Idaho. The technique uses a computer program to simulate two-dimensional, steady-state ground-water flow. Hydrologic data for the 1980 water year were used to calculate recharge rates, boundary fluxes, and spring discharges. Ground-water use was estimated from irrigated land maps and crop consumptive-use figures. These estimates of ground-water withdrawal, recharge rates, and boundary flux, along with leakance, were used as known values in the model calibration of transmissivity. Leakance values were adjusted between regression solutions by comparing model-calculated to measured spring discharges. In other simulations, recharge and leakance also were calibrated as prior-information regression parameters, which limits the variation of these parameters using a normalized standard error of estimate. Results from a best-fit model indicate a wide areal range in transmissivity from about 0.05 to 44 feet squared per second and in leakance from about 2.2x10 -9 to 6.0 x 10 -8 feet per second per foot. Along with parameter values, model statistics also were calculated, including the coefficient of correlation between calculated and observed head (0.996), the standard error of the estimates for head (40 feet), and the parameter coefficients of variation (about 10-40 percent). Additional boundary flux was added in some areas during calibration to achieve proper fit to ground-water flow directions. Model fit improved significantly when areas that violated model assumptions were removed. It also improved slightly when y-direction (northwest-southeast) transmissivity values were larger than x-direction (northeast-southwest) transmissivity values. The model was most sensitive to changes in recharge, and in some areas, to changes in transmissivity, particularly near the spring discharge area from Milner Dam to King Hill.

  2. UCODE, a computer code for universal inverse modeling

    USGS Publications Warehouse

    Poeter, E.P.; Hill, M.C.

    1999-01-01

    This article presents the US Geological Survey computer program UCODE, which was developed in collaboration with the US Army Corps of Engineers Waterways Experiment Station and the International Ground Water Modeling Center of the Colorado School of Mines. UCODE performs inverse modeling, posed as a parameter-estimation problem, using nonlinear regression. Any application model or set of models can be used; the only requirement is that they have numerical (ASCII or text only) input and output files and that the numbers in these files have sufficient significant digits. Application models can include preprocessors and postprocessors as well as models related to the processes of interest (physical, chemical and so on), making UCODE extremely powerful for model calibration. Estimated parameters can be defined flexibly with user-specified functions. Observations to be matched in the regression can be any quantity for which a simulated equivalent value can be produced, thus simulated equivalent values are calculated using values that appear in the application model output files and can be manipulated with additive and multiplicative functions, if necessary. Prior, or direct, information on estimated parameters also can be included in the regression. The nonlinear regression problem is solved by minimizing a weighted least-squares objective function with respect to the parameter values using a modified Gauss-Newton method. Sensitivities needed for the method are calculated approximately by forward or central differences and problems and solutions related to this approximation are discussed. Statistics are calculated and printed for use in (1) diagnosing inadequate data or identifying parameters that probably cannot be estimated with the available data, (2) evaluating estimated parameter values, (3) evaluating the model representation of the actual processes and (4) quantifying the uncertainty of model simulated values. UCODE is intended for use on any computer operating system: it consists of algorithms programmed in perl, a freeware language designed for text manipulation and Fortran90, which efficiently performs numerical calculations.

  3. Impact of orbit modeling on DORIS station position and Earth rotation estimates

    NASA Astrophysics Data System (ADS)

    Štěpánek, Petr; Rodriguez-Solano, Carlos Javier; Hugentobler, Urs; Filler, Vratislav

    2014-04-01

    The high precision of estimated station coordinates and Earth rotation parameters (ERP) obtained from satellite geodetic techniques is based on the precise determination of the satellite orbit. This paper focuses on the analysis of the impact of different orbit parameterizations on the accuracy of station coordinates and the ERPs derived from DORIS observations. In a series of experiments the DORIS data from the complete year 2011 were processed with different orbit model settings. First, the impact of precise modeling of the non-conservative forces on geodetic parameters was compared with results obtained with an empirical-stochastic modeling approach. Second, the temporal spacing of drag scaling parameters was tested. Third, the impact of estimating once-per-revolution harmonic accelerations in cross-track direction was analyzed. And fourth, two different approaches for solar radiation pressure (SRP) handling were compared, namely adjusting SRP scaling parameter or fixing it on pre-defined values. Our analyses confirm that the empirical-stochastic orbit modeling approach, which does not require satellite attitude information and macro models, results for most of the monitored station parameters in comparable accuracy as the dynamical model that employs precise non-conservative force modeling. However, the dynamical orbit model leads to a reduction of the RMS values for the estimated rotation pole coordinates by 17% for x-pole and 12% for y-pole. The experiments show that adjusting atmospheric drag scaling parameters each 30 min is appropriate for DORIS solutions. Moreover, it was shown that the adjustment of cross-track once-per-revolution empirical parameter increases the RMS of the estimated Earth rotation pole coordinates. With recent data it was however not possible to confirm the previously known high annual variation in the estimated geocenter z-translation series as well as its mitigation by fixing the SRP parameters on pre-defined values.

  4. Computational tools for fitting the Hill equation to dose-response curves.

    PubMed

    Gadagkar, Sudhindra R; Call, Gerald B

    2015-01-01

    Many biological response curves commonly assume a sigmoidal shape that can be approximated well by means of the 4-parameter nonlinear logistic equation, also called the Hill equation. However, estimation of the Hill equation parameters requires access to commercial software or the ability to write computer code. Here we present two user-friendly and freely available computer programs to fit the Hill equation - a Solver-based Microsoft Excel template and a stand-alone GUI-based "point and click" program, called HEPB. Both computer programs use the iterative method to estimate two of the Hill equation parameters (EC50 and the Hill slope), while constraining the values of the other two parameters (the minimum and maximum asymptotes of the response variable) to fit the Hill equation to the data. In addition, HEPB draws the prediction band at a user-defined confidence level, and determines the EC50 value for each of the limits of this band to give boundary values that help objectively delineate sensitive, normal and resistant responses to the drug being tested. Both programs were tested by analyzing twelve datasets that varied widely in data values, sample size and slope, and were found to yield estimates of the Hill equation parameters that were essentially identical to those provided by commercial software such as GraphPad Prism and nls, the statistical package in the programming language R. The Excel template provides a means to estimate the parameters of the Hill equation and plot the regression line in a familiar Microsoft Office environment. HEPB, in addition to providing the above results, also computes the prediction band for the data at a user-defined level of confidence, and determines objective cut-off values to distinguish among response types (sensitive, normal and resistant). Both programs are found to yield estimated values that are essentially the same as those from standard software such as GraphPad Prism and the R-based nls. Furthermore, HEPB also has the option to simulate 500 response values based on the range of values of the dose variable in the original data and the fit of the Hill equation to that data. Copyright © 2014. Published by Elsevier Inc.

  5. Models based on value and probability in health improve shared decision making.

    PubMed

    Ortendahl, Monica

    2008-10-01

    Diagnostic reasoning and treatment decisions are a key competence of doctors. A model based on values and probability provides a conceptual framework for clinical judgments and decisions, and also facilitates the integration of clinical and biomedical knowledge into a diagnostic decision. Both value and probability are usually estimated values in clinical decision making. Therefore, model assumptions and parameter estimates should be continually assessed against data, and models should be revised accordingly. Introducing parameter estimates for both value and probability, which usually pertain in clinical work, gives the model labelled subjective expected utility. Estimated values and probabilities are involved sequentially for every step in the decision-making process. Introducing decision-analytic modelling gives a more complete picture of variables that influence the decisions carried out by the doctor and the patient. A model revised for perceived values and probabilities by both the doctor and the patient could be used as a tool for engaging in a mutual and shared decision-making process in clinical work.

  6. A Bayesian Approach to Determination of F, D, and Z Values Used in Steam Sterilization Validation.

    PubMed

    Faya, Paul; Stamey, James D; Seaman, John W

    2017-01-01

    For manufacturers of sterile drug products, steam sterilization is a common method used to provide assurance of the sterility of manufacturing equipment and products. The validation of sterilization processes is a regulatory requirement and relies upon the estimation of key resistance parameters of microorganisms. Traditional methods have relied upon point estimates for the resistance parameters. In this paper, we propose a Bayesian method for estimation of the well-known D T , z , and F o values that are used in the development and validation of sterilization processes. A Bayesian approach allows the uncertainty about these values to be modeled using probability distributions, thereby providing a fully risk-based approach to measures of sterility assurance. An example is given using the survivor curve and fraction negative methods for estimation of resistance parameters, and we present a means by which a probabilistic conclusion can be made regarding the ability of a process to achieve a specified sterility criterion. LAY ABSTRACT: For manufacturers of sterile drug products, steam sterilization is a common method used to provide assurance of the sterility of manufacturing equipment and products. The validation of sterilization processes is a regulatory requirement and relies upon the estimation of key resistance parameters of microorganisms. Traditional methods have relied upon point estimates for the resistance parameters. In this paper, we propose a Bayesian method for estimation of the critical process parameters that are evaluated in the development and validation of sterilization processes. A Bayesian approach allows the uncertainty about these parameters to be modeled using probability distributions, thereby providing a fully risk-based approach to measures of sterility assurance. An example is given using the survivor curve and fraction negative methods for estimation of resistance parameters, and we present a means by which a probabilistic conclusion can be made regarding the ability of a process to achieve a specified sterility criterion. © PDA, Inc. 2017.

  7. Estimation of teleported and gained parameters in a non-inertial frame

    NASA Astrophysics Data System (ADS)

    Metwally, N.

    2017-04-01

    Quantum Fisher information is introduced as a measure of estimating the teleported information between two users, one of which is uniformly accelerated. We show that the final teleported state depends on the initial parameters, in addition to the gained parameters during the teleportation process. The estimation degree of these parameters depends on the value of the acceleration, the used single mode approximation (within/beyond), the type of encoded information (classic/quantum) in the teleported state, and the entanglement of the initial communication channel. The estimation degree of the parameters can be maximized if the partners teleport classical information.

  8. 40 CFR 98.315 - Procedures for estimating missing data.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... measured parameters used in the GHG emissions calculations is required (e.g., carbon content values, etc... such estimates. (a) For each missing value of the monthly carbon content of calcined petroleum coke the substitute data value shall be the arithmetic average of the quality-assured values of carbon contents for...

  9. Evaluation of dynamically downscaled extreme temperature using a spatially-aggregated generalized extreme value (GEV) model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Jiali; Han, Yuefeng; Stein, Michael L.

    2016-02-10

    The Weather Research and Forecast (WRF) model downscaling skill in extreme maximum daily temperature is evaluated by using the generalized extreme value (GEV) distribution. While the GEV distribution has been used extensively in climatology and meteorology for estimating probabilities of extreme events, accurately estimating GEV parameters based on data from a single pixel can be difficult, even with fairly long data records. This work proposes a simple method assuming that the shape parameter, the most difficult of the three parameters to estimate, does not vary over a relatively large region. This approach is applied to evaluate 31-year WRF-downscaled extreme maximummore » temperature through comparison with North American Regional Reanalysis (NARR) data. Uncertainty in GEV parameter estimates and the statistical significance in the differences of estimates between WRF and NARR are accounted for by conducting bootstrap resampling. Despite certain biases over parts of the United States, overall, WRF shows good agreement with NARR in the spatial pattern and magnitudes of GEV parameter estimates. Both WRF and NARR show a significant increase in extreme maximum temperature over the southern Great Plains and southeastern United States in January and over the western United States in July. The GEV model shows clear benefits from the regionally constant shape parameter assumption, for example, leading to estimates of the location and scale parameters of the model that show coherent spatial patterns.« less

  10. A Hierarchical Bayesian Model for Calibrating Estimates of Species Divergence Times

    PubMed Central

    Heath, Tracy A.

    2012-01-01

    In Bayesian divergence time estimation methods, incorporating calibrating information from the fossil record is commonly done by assigning prior densities to ancestral nodes in the tree. Calibration prior densities are typically parametric distributions offset by minimum age estimates provided by the fossil record. Specification of the parameters of calibration densities requires the user to quantify his or her prior knowledge of the age of the ancestral node relative to the age of its calibrating fossil. The values of these parameters can, potentially, result in biased estimates of node ages if they lead to overly informative prior distributions. Accordingly, determining parameter values that lead to adequate prior densities is not straightforward. In this study, I present a hierarchical Bayesian model for calibrating divergence time analyses with multiple fossil age constraints. This approach applies a Dirichlet process prior as a hyperprior on the parameters of calibration prior densities. Specifically, this model assumes that the rate parameters of exponential prior distributions on calibrated nodes are distributed according to a Dirichlet process, whereby the rate parameters are clustered into distinct parameter categories. Both simulated and biological data are analyzed to evaluate the performance of the Dirichlet process hyperprior. Compared with fixed exponential prior densities, the hierarchical Bayesian approach results in more accurate and precise estimates of internal node ages. When this hyperprior is applied using Markov chain Monte Carlo methods, the ages of calibrated nodes are sampled from mixtures of exponential distributions and uncertainty in the values of calibration density parameters is taken into account. PMID:22334343

  11. Determining the accuracy of maximum likelihood parameter estimates with colored residuals

    NASA Technical Reports Server (NTRS)

    Morelli, Eugene A.; Klein, Vladislav

    1994-01-01

    An important part of building high fidelity mathematical models based on measured data is calculating the accuracy associated with statistical estimates of the model parameters. Indeed, without some idea of the accuracy of parameter estimates, the estimates themselves have limited value. In this work, an expression based on theoretical analysis was developed to properly compute parameter accuracy measures for maximum likelihood estimates with colored residuals. This result is important because experience from the analysis of measured data reveals that the residuals from maximum likelihood estimation are almost always colored. The calculations involved can be appended to conventional maximum likelihood estimation algorithms. Simulated data runs were used to show that the parameter accuracy measures computed with this technique accurately reflect the quality of the parameter estimates from maximum likelihood estimation without the need for analysis of the output residuals in the frequency domain or heuristically determined multiplication factors. The result is general, although the application studied here is maximum likelihood estimation of aerodynamic model parameters from flight test data.

  12. Evaluation of assigned-value uncertainty for complex calibrator value assignment processes: a prealbumin example.

    PubMed

    Middleton, John; Vaks, Jeffrey E

    2007-04-01

    Errors of calibrator-assigned values lead to errors in the testing of patient samples. The ability to estimate the uncertainties of calibrator-assigned values and other variables minimizes errors in testing processes. International Organization of Standardization guidelines provide simple equations for the estimation of calibrator uncertainty with simple value-assignment processes, but other methods are needed to estimate uncertainty in complex processes. We estimated the assigned-value uncertainty with a Monte Carlo computer simulation of a complex value-assignment process, based on a formalized description of the process, with measurement parameters estimated experimentally. This method was applied to study uncertainty of a multilevel calibrator value assignment for a prealbumin immunoassay. The simulation results showed that the component of the uncertainty added by the process of value transfer from the reference material CRM470 to the calibrator is smaller than that of the reference material itself (<0.8% vs 3.7%). Varying the process parameters in the simulation model allowed for optimizing the process, while keeping the added uncertainty small. The patient result uncertainty caused by the calibrator uncertainty was also found to be small. This method of estimating uncertainty is a powerful tool that allows for estimation of calibrator uncertainty for optimization of various value assignment processes, with a reduced number of measurements and reagent costs, while satisfying the requirements to uncertainty. The new method expands and augments existing methods to allow estimation of uncertainty in complex processes.

  13. THE ON-SITE ON-LINE TOOL FOR SITE ASSESSMENT CALCULATIONS

    EPA Science Inventory

    State and Federal Agency personnel often receive modeling reports with undocumented parameter values. The reports give parameter values, but often no indication if the value was measured, taken from the literature, the result of calibration, or some type of estimate. Recent examp...

  14. 40 CFR 98.275 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... for estimating missing data. A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, according to the...

  15. 40 CFR 98.365 - Procedures for estimating missing data.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, according to the...

  16. 40 CFR 98.365 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, according to the...

  17. 40 CFR 98.175 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  18. 40 CFR 98.345 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... for estimating missing data. A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, according to the...

  19. 40 CFR 98.465 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, in accordance with...

  20. 40 CFR 98.355 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... for estimating missing data. A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter must be used in the calculations, according to the following...

  1. 40 CFR 98.215 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... for estimating missing data. (a) A complete record of all measured parameters used in the GHG... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  2. 40 CFR 98.55 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... substitute data value for the missing parameter shall be used in the calculations as specified in paragraphs...

  3. 40 CFR 98.155 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... Procedures for estimating missing data. (a) A complete record of all measured parameters used in the GHG...), a substitute data value for the missing parameter shall be used in the calculations, according to...

  4. 40 CFR 98.125 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... unavailable, a substitute data value for the missing parameter must be used in the calculations as specified...

  5. 40 CFR 98.265 - Procedures for estimating missing data.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  6. 40 CFR 98.175 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  7. 40 CFR 98.125 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... unavailable, a substitute data value for the missing parameter must be used in the calculations as specified...

  8. 40 CFR 98.275 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... for estimating missing data. A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, according to the...

  9. 40 CFR 98.215 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... for estimating missing data. (a) A complete record of all measured parameters used in the GHG... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  10. 40 CFR 98.345 - Procedures for estimating missing data.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Procedures for estimating missing data... for estimating missing data. A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, according to the...

  11. 40 CFR 98.345 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... for estimating missing data. A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, according to the...

  12. 40 CFR 98.155 - Procedures for estimating missing data.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Procedures for estimating missing data... Procedures for estimating missing data. (a) A complete record of all measured parameters used in the GHG...), a substitute data value for the missing parameter shall be used in the calculations, according to...

  13. 40 CFR 98.115 - Procedures for estimating missing data.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  14. 40 CFR 98.325 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, in accordance with...

  15. 40 CFR 98.175 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  16. 40 CFR 98.215 - Procedures for estimating missing data.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Procedures for estimating missing data... for estimating missing data. (a) A complete record of all measured parameters used in the GHG... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  17. 40 CFR 98.55 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... substitute data value for the missing parameter shall be used in the calculations as specified in paragraphs...

  18. 40 CFR 98.325 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, in accordance with...

  19. 40 CFR 98.275 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... for estimating missing data. A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, according to the...

  20. 40 CFR 98.215 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... for estimating missing data. (a) A complete record of all measured parameters used in the GHG... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  1. 40 CFR 98.355 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... for estimating missing data. A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter must be used in the calculations, according to the following...

  2. 40 CFR 98.275 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... for estimating missing data. A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, according to the...

  3. 40 CFR 98.155 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... Procedures for estimating missing data. (a) A complete record of all measured parameters used in the GHG...), a substitute data value for the missing parameter shall be used in the calculations, according to...

  4. 40 CFR 98.365 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, according to the...

  5. 40 CFR 98.65 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... substitute data value for the missing parameter shall be used in the calculations, according to the following...

  6. 40 CFR 98.65 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... substitute data value for the missing parameter shall be used in the calculations, according to the following...

  7. 40 CFR 98.115 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  8. 40 CFR 98.115 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  9. 40 CFR 98.115 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  10. 40 CFR 98.225 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... substitute data value for the missing parameter shall be used in the calculations as specified in paragraphs...

  11. 40 CFR 98.175 - Procedures for estimating missing data.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  12. 40 CFR 98.115 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  13. 40 CFR 98.125 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... unavailable, a substitute data value for the missing parameter must be used in the calculations as specified...

  14. 40 CFR 98.355 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... for estimating missing data. A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter must be used in the calculations, according to the following...

  15. 40 CFR 98.465 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, in accordance with...

  16. 40 CFR 98.325 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, in accordance with...

  17. 40 CFR 98.365 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, according to the...

  18. 40 CFR 98.465 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, in accordance with...

  19. 40 CFR 98.225 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... substitute data value for the missing parameter shall be used in the calculations as specified in paragraphs...

  20. 40 CFR 98.345 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... for estimating missing data. A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, according to the...

  1. 40 CFR 98.65 - Procedures for estimating missing data.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... substitute data value for the missing parameter shall be used in the calculations, according to the following...

  2. 40 CFR 98.125 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... unavailable, a substitute data value for the missing parameter must be used in the calculations as specified...

  3. 40 CFR 98.55 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... substitute data value for the missing parameter shall be used in the calculations as specified in paragraphs...

  4. 40 CFR 98.155 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... Procedures for estimating missing data. (a) A complete record of all measured parameters used in the GHG...), a substitute data value for the missing parameter shall be used in the calculations, according to...

  5. 40 CFR 98.55 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... substitute data value for the missing parameter shall be used in the calculations as specified in paragraphs...

  6. 40 CFR 98.65 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... substitute data value for the missing parameter shall be used in the calculations, according to the following...

  7. 40 CFR 98.265 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... substitute data value for the missing parameter must be used in the calculations as specified in paragraphs...

  8. 40 CFR 98.355 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... for estimating missing data. A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter must be used in the calculations, according to the following...

  9. 40 CFR 98.345 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... for estimating missing data. A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, according to the...

  10. 40 CFR 98.215 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... for estimating missing data. (a) A complete record of all measured parameters used in the GHG... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  11. 40 CFR 98.325 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, in accordance with...

  12. 40 CFR 98.465 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, in accordance with...

  13. 40 CFR 98.175 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  14. 40 CFR 98.225 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... substitute data value for the missing parameter shall be used in the calculations as specified in paragraphs...

  15. 40 CFR 98.155 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... Procedures for estimating missing data. (a) A complete record of all measured parameters used in the GHG...), a substitute data value for the missing parameter shall be used in the calculations, according to...

  16. 40 CFR 98.65 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... substitute data value for the missing parameter shall be used in the calculations, according to the following...

  17. 40 CFR 98.225 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... substitute data value for the missing parameter shall be used in the calculations as specified in paragraphs...

  18. 40 CFR 98.365 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, according to the...

  19. Brute force meets Bruno force in parameter optimisation: introduction of novel constraints for parameter accuracy improvement by symbolic computation.

    PubMed

    Nakatsui, M; Horimoto, K; Lemaire, F; Ürgüplü, A; Sedoglavic, A; Boulier, F

    2011-09-01

    Recent remarkable advances in computer performance have enabled us to estimate parameter values by the huge power of numerical computation, the so-called 'Brute force', resulting in the high-speed simultaneous estimation of a large number of parameter values. However, these advancements have not been fully utilised to improve the accuracy of parameter estimation. Here the authors review a novel method for parameter estimation using symbolic computation power, 'Bruno force', named after Bruno Buchberger, who found the Gröbner base. In the method, the objective functions combining the symbolic computation techniques are formulated. First, the authors utilise a symbolic computation technique, differential elimination, which symbolically reduces an equivalent system of differential equations to a system in a given model. Second, since its equivalent system is frequently composed of large equations, the system is further simplified by another symbolic computation. The performance of the authors' method for parameter accuracy improvement is illustrated by two representative models in biology, a simple cascade model and a negative feedback model in comparison with the previous numerical methods. Finally, the limits and extensions of the authors' method are discussed, in terms of the possible power of 'Bruno force' for the development of a new horizon in parameter estimation.

  20. A comparison between Gauss-Newton and Markov chain Monte Carlo basedmethods for inverting spectral induced polarization data for Cole-Coleparameters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chen, Jinsong; Kemna, Andreas; Hubbard, Susan S.

    2008-05-15

    We develop a Bayesian model to invert spectral induced polarization (SIP) data for Cole-Cole parameters using Markov chain Monte Carlo (MCMC) sampling methods. We compare the performance of the MCMC based stochastic method with an iterative Gauss-Newton based deterministic method for Cole-Cole parameter estimation through inversion of synthetic and laboratory SIP data. The Gauss-Newton based method can provide an optimal solution for given objective functions under constraints, but the obtained optimal solution generally depends on the choice of initial values and the estimated uncertainty information is often inaccurate or insufficient. In contrast, the MCMC based inversion method provides extensive globalmore » information on unknown parameters, such as the marginal probability distribution functions, from which we can obtain better estimates and tighter uncertainty bounds of the parameters than with the deterministic method. Additionally, the results obtained with the MCMC method are independent of the choice of initial values. Because the MCMC based method does not explicitly offer single optimal solution for given objective functions, the deterministic and stochastic methods can complement each other. For example, the stochastic method can first be used to obtain the means of the unknown parameters by starting from an arbitrary set of initial values and the deterministic method can then be initiated using the means as starting values to obtain the optimal estimates of the Cole-Cole parameters.« less

  1. Parameter interdependence and uncertainty induced by lumping in a hydrologic model

    NASA Astrophysics Data System (ADS)

    Gallagher, Mark R.; Doherty, John

    2007-05-01

    Throughout the world, watershed modeling is undertaken using lumped parameter hydrologic models that represent real-world processes in a manner that is at once abstract, but nevertheless relies on algorithms that reflect real-world processes and parameters that reflect real-world hydraulic properties. In most cases, values are assigned to the parameters of such models through calibration against flows at watershed outlets. One criterion by which the utility of the model and the success of the calibration process are judged is that realistic values are assigned to parameters through this process. This study employs regularization theory to examine the relationship between lumped parameters and corresponding real-world hydraulic properties. It demonstrates that any kind of parameter lumping or averaging can induce a substantial amount of "structural noise," which devices such as Box-Cox transformation of flows and autoregressive moving average (ARMA) modeling of residuals are unlikely to render homoscedastic and uncorrelated. Furthermore, values estimated for lumped parameters are unlikely to represent average values of the hydraulic properties after which they are named and are often contaminated to a greater or lesser degree by the values of hydraulic properties which they do not purport to represent at all. As a result, the question of how rigidly they should be bounded during the parameter estimation process is still an open one.

  2. Quantification of tumor perfusion using dynamic contrast-enhanced ultrasound: impact of mathematical modeling

    NASA Astrophysics Data System (ADS)

    Doury, Maxime; Dizeux, Alexandre; de Cesare, Alain; Lucidarme, Olivier; Pellot-Barakat, Claire; Bridal, S. Lori; Frouin, Frédérique

    2017-02-01

    Dynamic contrast-enhanced ultrasound has been proposed to monitor tumor therapy, as a complement to volume measurements. To assess the variability of perfusion parameters in ideal conditions, four consecutive test-retest studies were acquired in a mouse tumor model, using controlled injections. The impact of mathematical modeling on parameter variability was then investigated. Coefficients of variation (CV) of tissue blood volume (BV) and tissue blood flow (BF) based-parameters were estimated inside 32 sub-regions of the tumors, comparing the log-normal (LN) model with a one-compartment model fed by an arterial input function (AIF) and improved by the introduction of a time delay parameter. Relative perfusion parameters were also estimated by normalization of the LN parameters and normalization of the one-compartment parameters estimated with the AIF, using a reference tissue (RT) region. A direct estimation (rRTd) of relative parameters, based on the one-compartment model without using the AIF, was also obtained by using the kinetics inside the RT region. Results of test-retest studies show that absolute regional parameters have high CV, whatever the approach, with median values of about 30% for BV, and 40% for BF. The positive impact of normalization was established, showing a coherent estimation of relative parameters, with reduced CV (about 20% for BV and 30% for BF using the rRTd approach). These values were significantly lower (p  <  0.05) than the CV of absolute parameters. The rRTd approach provided the smallest CV and should be preferred for estimating relative perfusion parameters.

  3. PROUCL 4.0 SOFTWARE

    EPA Science Inventory

    Statistical inference, including both estimation and hypotheses testing approaches, is routinely used to: estimate environmental parameters of interest, such as exposure point concentration (EPC) terms, not-to-exceed values, and background level threshold values (BTVs) for contam...

  4. Estimation of soil hydraulic properties with microwave techniques

    NASA Technical Reports Server (NTRS)

    Oneill, P. E.; Gurney, R. J.; Camillo, P. J.

    1985-01-01

    Useful quantitative information about soil properties may be obtained by calibrating energy and moisture balance models with remotely sensed data. A soil physics model solves heat and moisture flux equations in the soil profile and is driven by the surface energy balance. Model generated surface temperature and soil moisture and temperature profiles are then used in a microwave emission model to predict the soil brightness temperature. The model hydraulic parameters are varied until the predicted temperatures agree with the remotely sensed values. This method is used to estimate values for saturated hydraulic conductivity, saturated matrix potential, and a soil texture parameter. The conductivity agreed well with a value measured with an infiltration ring and the other parameters agreed with values in the literature.

  5. Statistical Bayesian method for reliability evaluation based on ADT data

    NASA Astrophysics Data System (ADS)

    Lu, Dawei; Wang, Lizhi; Sun, Yusheng; Wang, Xiaohong

    2018-05-01

    Accelerated degradation testing (ADT) is frequently conducted in the laboratory to predict the products’ reliability under normal operating conditions. Two kinds of methods, degradation path models and stochastic process models, are utilized to analyze degradation data and the latter one is the most popular method. However, some limitations like imprecise solution process and estimation result of degradation ratio still exist, which may affect the accuracy of the acceleration model and the extrapolation value. Moreover, the conducted solution of this problem, Bayesian method, lose key information when unifying the degradation data. In this paper, a new data processing and parameter inference method based on Bayesian method is proposed to handle degradation data and solve the problems above. First, Wiener process and acceleration model is chosen; Second, the initial values of degradation model and parameters of prior and posterior distribution under each level is calculated with updating and iteration of estimation values; Third, the lifetime and reliability values are estimated on the basis of the estimation parameters; Finally, a case study is provided to demonstrate the validity of the proposed method. The results illustrate that the proposed method is quite effective and accuracy in estimating the lifetime and reliability of a product.

  6. Variability of non-Gaussian diffusion MRI and intravoxel incoherent motion (IVIM) measurements in the breast.

    PubMed

    Iima, Mami; Kataoka, Masako; Kanao, Shotaro; Kawai, Makiko; Onishi, Natsuko; Koyasu, Sho; Murata, Katsutoshi; Ohashi, Akane; Sakaguchi, Rena; Togashi, Kaori

    2018-01-01

    We prospectively examined the variability of non-Gaussian diffusion magnetic resonance imaging (MRI) and intravoxel incoherent motion (IVIM) measurements with different numbers of b-values and excitations in normal breast tissue and breast lesions. Thirteen volunteers and fourteen patients with breast lesions (seven malignant, eight benign; one patient had bilateral lesions) were recruited in this prospective study (approved by the Internal Review Board). Diffusion-weighted MRI was performed with 16 b-values (0-2500 s/mm2 with one number of excitations [NEX]) and five b-values (0-2500 s/mm2, 3 NEX), using a 3T breast MRI. Intravoxel incoherent motion (flowing blood volume fraction [fIVIM] and pseudodiffusion coefficient [D*]) and non-Gaussian diffusion (theoretical apparent diffusion coefficient [ADC] at b value of 0 sec/mm2 [ADC0] and kurtosis [K]) parameters were estimated from IVIM and Kurtosis models using 16 b-values, and synthetic apparent diffusion coefficient (sADC) values were obtained from two key b-values. The variabilities between and within subjects and between different diffusion acquisition methods were estimated. There were no statistical differences in ADC0, K, or sADC values between the different b-values or NEX. A good agreement of diffusion parameters was observed between 16 b-values (one NEX), five b-values (one NEX), and five b-values (three NEX) in normal breast tissue or breast lesions. Insufficient agreement was observed for IVIM parameters. There were no statistical differences in the non-Gaussian diffusion MRI estimated values obtained from a different number of b-values or excitations in normal breast tissue or breast lesions. These data suggest that a limited MRI protocol using a few b-values might be relevant in a clinical setting for the estimation of non-Gaussian diffusion MRI parameters in normal breast tissue and breast lesions.

  7. Variability of non-Gaussian diffusion MRI and intravoxel incoherent motion (IVIM) measurements in the breast

    PubMed Central

    Kataoka, Masako; Kanao, Shotaro; Kawai, Makiko; Onishi, Natsuko; Koyasu, Sho; Murata, Katsutoshi; Ohashi, Akane; Sakaguchi, Rena; Togashi, Kaori

    2018-01-01

    We prospectively examined the variability of non-Gaussian diffusion magnetic resonance imaging (MRI) and intravoxel incoherent motion (IVIM) measurements with different numbers of b-values and excitations in normal breast tissue and breast lesions. Thirteen volunteers and fourteen patients with breast lesions (seven malignant, eight benign; one patient had bilateral lesions) were recruited in this prospective study (approved by the Internal Review Board). Diffusion-weighted MRI was performed with 16 b-values (0–2500 s/mm2 with one number of excitations [NEX]) and five b-values (0–2500 s/mm2, 3 NEX), using a 3T breast MRI. Intravoxel incoherent motion (flowing blood volume fraction [fIVIM] and pseudodiffusion coefficient [D*]) and non-Gaussian diffusion (theoretical apparent diffusion coefficient [ADC] at b value of 0 sec/mm2 [ADC0] and kurtosis [K]) parameters were estimated from IVIM and Kurtosis models using 16 b-values, and synthetic apparent diffusion coefficient (sADC) values were obtained from two key b-values. The variabilities between and within subjects and between different diffusion acquisition methods were estimated. There were no statistical differences in ADC0, K, or sADC values between the different b-values or NEX. A good agreement of diffusion parameters was observed between 16 b-values (one NEX), five b-values (one NEX), and five b-values (three NEX) in normal breast tissue or breast lesions. Insufficient agreement was observed for IVIM parameters. There were no statistical differences in the non-Gaussian diffusion MRI estimated values obtained from a different number of b-values or excitations in normal breast tissue or breast lesions. These data suggest that a limited MRI protocol using a few b-values might be relevant in a clinical setting for the estimation of non-Gaussian diffusion MRI parameters in normal breast tissue and breast lesions. PMID:29494639

  8. Probabilistic parameter estimation of activated sludge processes using Markov Chain Monte Carlo.

    PubMed

    Sharifi, Soroosh; Murthy, Sudhir; Takács, Imre; Massoudieh, Arash

    2014-03-01

    One of the most important challenges in making activated sludge models (ASMs) applicable to design problems is identifying the values of its many stoichiometric and kinetic parameters. When wastewater characteristics data from full-scale biological treatment systems are used for parameter estimation, several sources of uncertainty, including uncertainty in measured data, external forcing (e.g. influent characteristics), and model structural errors influence the value of the estimated parameters. This paper presents a Bayesian hierarchical modeling framework for the probabilistic estimation of activated sludge process parameters. The method provides the joint probability density functions (JPDFs) of stoichiometric and kinetic parameters by updating prior information regarding the parameters obtained from expert knowledge and literature. The method also provides the posterior correlations between the parameters, as well as a measure of sensitivity of the different constituents with respect to the parameters. This information can be used to design experiments to provide higher information content regarding certain parameters. The method is illustrated using the ASM1 model to describe synthetically generated data from a hypothetical biological treatment system. The results indicate that data from full-scale systems can narrow down the ranges of some parameters substantially whereas the amount of information they provide regarding other parameters is small, due to either large correlations between some of the parameters or a lack of sensitivity with respect to the parameters. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. A Phenomenological Model for Circadian and Sleep Allostatic Modulation of Plasma Cortisol Concentration

    DTIC Science & Technology

    2012-09-25

    amplitudes of the model’s produc- tion parameters (w, , s) and degradation parameters (kp, dc) because the estimates for all of these parameters... degradation parameters (kp, dc), because the estimates for all of these parameters are higher for group A than for group C. E1194 A MODEL OF...values of both production and degradation parameters (Table 3), but there is significant variability between subjects that is caused by underlying

  10. A Monte Carlo study of the impact of the choice of rectum volume definition on estimates of equivalent uniform doses and the volume parameter

    NASA Astrophysics Data System (ADS)

    Kvinnsland, Yngve; Muren, Ludvig Paul; Dahl, Olav

    2004-08-01

    Calculations of normal tissue complication probability (NTCP) values for the rectum are difficult because it is a hollow, non-rigid, organ. Finding the true cumulative dose distribution for a number of treatment fractions requires a CT scan before each treatment fraction. This is labour intensive, and several surrogate distributions have therefore been suggested, such as dose wall histograms, dose surface histograms and histograms for the solid rectum, with and without margins. In this study, a Monte Carlo method is used to investigate the relationships between the cumulative dose distributions based on all treatment fractions and the above-mentioned histograms that are based on one CT scan only, in terms of equivalent uniform dose. Furthermore, the effect of a specific choice of histogram on estimates of the volume parameter of the probit NTCP model was investigated. It was found that the solid rectum and the rectum wall histograms (without margins) gave equivalent uniform doses with an expected value close to the values calculated from the cumulative dose distributions in the rectum wall. With the number of patients available in this study the standard deviations of the estimates of the volume parameter were large, and it was not possible to decide which volume gave the best estimates of the volume parameter, but there were distinct differences in the mean values of the values obtained.

  11. Inverse sequential detection of parameter changes in developing time series

    NASA Technical Reports Server (NTRS)

    Radok, Uwe; Brown, Timothy J.

    1992-01-01

    Progressive values of two probabilities are obtained for parameter estimates derived from an existing set of values and from the same set enlarged by one or more new values, respectively. One probability is that of erroneously preferring the second of these estimates for the existing data ('type 1 error'), while the second probability is that of erroneously accepting their estimates for the enlarged test ('type 2 error'). A more stable combined 'no change' probability which always falls between 0.5 and 0 is derived from the (logarithmic) width of the uncertainty region of an equivalent 'inverted' sequential probability ratio test (SPRT, Wald 1945) in which the error probabilities are calculated rather than prescribed. A parameter change is indicated when the compound probability undergoes a progressive decrease. The test is explicitly formulated and exemplified for Gaussian samples.

  12. Single neuron modeling and data assimilation in BNST neurons

    NASA Astrophysics Data System (ADS)

    Farsian, Reza

    Neurons, although tiny in size, are vastly complicated systems, which are responsible for the most basic yet essential functions of any nervous system. Even the most simple models of single neurons are usually high dimensional, nonlinear, and contain many parameters and states which are unobservable in a typical neurophysiological experiment. One of the most fundamental problems in experimental neurophysiology is the estimation of these parameters and states, since knowing their values is essential in identification, model construction, and forward prediction of biological neurons. Common methods of parameter and state estimation do not perform well for neural models due to their high dimensionality and nonlinearity. In this dissertation, two alternative approaches for parameters and state estimation of biological neurons have been demonstrated: dynamical parameter estimation (DPE) and a Markov Chain Monte Carlo (MCMC) method. The first method uses elements of chaos control and synchronization theory for parameter and state estimation. MCMC is a statistical approach which uses a path integral formulation to evaluate a mean and an error bound for these unobserved parameters and states. These methods have been applied to biological system of neurons in Bed Nucleus of Stria Termialis neurons (BNST) of rats. State and parameters of neurons in both systems were estimated, and their value were used for recreating a realistic model and predicting the behavior of the neurons successfully. The knowledge of biological parameters can ultimately provide a better understanding of the internal dynamics of a neuron in order to build robust models of neuron networks.

  13. An iterative procedure for obtaining maximum-likelihood estimates of the parameters for a mixture of normal distributions, Addendum

    NASA Technical Reports Server (NTRS)

    Peters, B. C., Jr.; Walker, H. F.

    1975-01-01

    New results and insights concerning a previously published iterative procedure for obtaining maximum-likelihood estimates of the parameters for a mixture of normal distributions were discussed. It was shown that the procedure converges locally to the consistent maximum likelihood estimate as long as a specified parameter is bounded between two limits. Bound values were given to yield optimal local convergence.

  14. SP_Ace: Stellar Parameters And Chemical abundances Estimator

    NASA Astrophysics Data System (ADS)

    Boeche, C.; Grebel, E. K.

    2018-05-01

    SP_Ace (Stellar Parameters And Chemical abundances Estimator) estimates the stellar parameters Teff, log g, [M/H], and elemental abundances. It employs 1D stellar atmosphere models in Local Thermodynamic Equilibrium (LTE). The code is highly automated and suitable for analyzing the spectra of large spectroscopic surveys with low or medium spectral resolution (R = 2000-20 000). A web service for calculating these values with the software is also available.

  15. Estimation of key parameters in adaptive neuron model according to firing patterns based on improved particle swarm optimization algorithm

    NASA Astrophysics Data System (ADS)

    Yuan, Chunhua; Wang, Jiang; Yi, Guosheng

    2017-03-01

    Estimation of ion channel parameters is crucial to spike initiation of neurons. The biophysical neuron models have numerous ion channel parameters, but only a few of them play key roles in the firing patterns of the models. So we choose three parameters featuring the adaptation in the Ermentrout neuron model to be estimated. However, the traditional particle swarm optimization (PSO) algorithm is still easy to fall into local optimum and has the premature convergence phenomenon in the study of some problems. In this paper, we propose an improved method that uses a concave function and dynamic logistic chaotic mapping mixed to adjust the inertia weights of the fitness value, effectively improve the global convergence ability of the algorithm. The perfect predicting firing trajectories of the rebuilt model using the estimated parameters prove that only estimating a few important ion channel parameters can establish the model well and the proposed algorithm is effective. Estimations using two classic PSO algorithms are also compared to the improved PSO to verify that the algorithm proposed in this paper can avoid local optimum and quickly converge to the optimal value. The results provide important theoretical foundations for building biologically realistic neuron models.

  16. Transmuted of Rayleigh Distribution with Estimation and Application on Noise Signal

    NASA Astrophysics Data System (ADS)

    Ahmed, Suhad; Qasim, Zainab

    2018-05-01

    This paper deals with transforming one parameter Rayleigh distribution, into transmuted probability distribution through introducing a new parameter (λ), since this studied distribution is necessary in representing signal data distribution and failure data model the value of this transmuted parameter |λ| ≤ 1, is also estimated as well as the original parameter (⊖) by methods of moments and maximum likelihood using different sample size (n=25, 50, 75, 100) and comparing the results of estimation by statistical measure (mean square error, MSE).

  17. Modeling clear-sky solar radiation across a range of elevations in Hawai‘i: Comparing the use of input parameters at different temporal resolutions

    NASA Astrophysics Data System (ADS)

    Longman, Ryan J.; Giambelluca, Thomas W.; Frazier, Abby G.

    2012-01-01

    Estimates of clear sky global solar irradiance using the parametric model SPCTRAL2 were tested against clear sky radiation observations at four sites in Hawai`i using daily, mean monthly, and 1 year mean model parameter settings. Atmospheric parameters in SPCTRAL2 and similar models are usually set at site-specific values and are not varied to represent the effects of fluctuating humidity, aerosol amount and type, or ozone concentration, because time-dependent atmospheric parameter estimates are not available at most sites of interest. In this study, we sought to determine the added value of using time dependent as opposed to fixed model input parameter settings. At the AERONET site, Mauna Loa Observatory (MLO) on the island of Hawai`i, where daily measurements of atmospheric optical properties and hourly solar radiation observations are available, use of daily rather than 1 year mean aerosol parameter values reduced mean bias error (MBE) from 18 to 10 W m-2 and root mean square error from 25 to 17 W m-2. At three stations in the HaleNet climate network, located at elevations of 960, 1640, and 2590 m on the island of Maui, where aerosol-related parameter settings were interpolated from observed values for AERONET sites at MLO (3397 m) and Lāna`i (20 m), and precipitable water was estimated using radiosonde-derived humidity profiles from nearby Hilo, the model performed best when using constant 1 year mean parameter values. At HaleNet Station 152, for example, MBE was 18, 10, and 8 W m-2 for daily, monthly, and 1 year mean parameters, respectively.

  18. Modeling motor vehicle crashes using Poisson-gamma models: examining the effects of low sample mean values and small sample size on the estimation of the fixed dispersion parameter.

    PubMed

    Lord, Dominique

    2006-07-01

    There has been considerable research conducted on the development of statistical models for predicting crashes on highway facilities. Despite numerous advancements made for improving the estimation tools of statistical models, the most common probabilistic structure used for modeling motor vehicle crashes remains the traditional Poisson and Poisson-gamma (or Negative Binomial) distribution; when crash data exhibit over-dispersion, the Poisson-gamma model is usually the model of choice most favored by transportation safety modelers. Crash data collected for safety studies often have the unusual attributes of being characterized by low sample mean values. Studies have shown that the goodness-of-fit of statistical models produced from such datasets can be significantly affected. This issue has been defined as the "low mean problem" (LMP). Despite recent developments on methods to circumvent the LMP and test the goodness-of-fit of models developed using such datasets, no work has so far examined how the LMP affects the fixed dispersion parameter of Poisson-gamma models used for modeling motor vehicle crashes. The dispersion parameter plays an important role in many types of safety studies and should, therefore, be reliably estimated. The primary objective of this research project was to verify whether the LMP affects the estimation of the dispersion parameter and, if it is, to determine the magnitude of the problem. The secondary objective consisted of determining the effects of an unreliably estimated dispersion parameter on common analyses performed in highway safety studies. To accomplish the objectives of the study, a series of Poisson-gamma distributions were simulated using different values describing the mean, the dispersion parameter, and the sample size. Three estimators commonly used by transportation safety modelers for estimating the dispersion parameter of Poisson-gamma models were evaluated: the method of moments, the weighted regression, and the maximum likelihood method. In an attempt to complement the outcome of the simulation study, Poisson-gamma models were fitted to crash data collected in Toronto, Ont. characterized by a low sample mean and small sample size. The study shows that a low sample mean combined with a small sample size can seriously affect the estimation of the dispersion parameter, no matter which estimator is used within the estimation process. The probability the dispersion parameter becomes unreliably estimated increases significantly as the sample mean and sample size decrease. Consequently, the results show that an unreliably estimated dispersion parameter can significantly undermine empirical Bayes (EB) estimates as well as the estimation of confidence intervals for the gamma mean and predicted response. The paper ends with recommendations about minimizing the likelihood of producing Poisson-gamma models with an unreliable dispersion parameter for modeling motor vehicle crashes.

  19. Estimating the Expected Value of Sample Information Using the Probabilistic Sensitivity Analysis Sample

    PubMed Central

    Oakley, Jeremy E.; Brennan, Alan; Breeze, Penny

    2015-01-01

    Health economic decision-analytic models are used to estimate the expected net benefits of competing decision options. The true values of the input parameters of such models are rarely known with certainty, and it is often useful to quantify the value to the decision maker of reducing uncertainty through collecting new data. In the context of a particular decision problem, the value of a proposed research design can be quantified by its expected value of sample information (EVSI). EVSI is commonly estimated via a 2-level Monte Carlo procedure in which plausible data sets are generated in an outer loop, and then, conditional on these, the parameters of the decision model are updated via Bayes rule and sampled in an inner loop. At each iteration of the inner loop, the decision model is evaluated. This is computationally demanding and may be difficult if the posterior distribution of the model parameters conditional on sampled data is hard to sample from. We describe a fast nonparametric regression-based method for estimating per-patient EVSI that requires only the probabilistic sensitivity analysis sample (i.e., the set of samples drawn from the joint distribution of the parameters and the corresponding net benefits). The method avoids the need to sample from the posterior distributions of the parameters and avoids the need to rerun the model. The only requirement is that sample data sets can be generated. The method is applicable with a model of any complexity and with any specification of model parameter distribution. We demonstrate in a case study the superior efficiency of the regression method over the 2-level Monte Carlo method. PMID:25810269

  20. Equal Area Logistic Estimation for Item Response Theory

    NASA Astrophysics Data System (ADS)

    Lo, Shih-Ching; Wang, Kuo-Chang; Chang, Hsin-Li

    2009-08-01

    Item response theory (IRT) models use logistic functions exclusively as item response functions (IRFs). Applications of IRT models require obtaining the set of values for logistic function parameters that best fit an empirical data set. However, success in obtaining such set of values does not guarantee that the constructs they represent actually exist, for the adequacy of a model is not sustained by the possibility of estimating parameters. In this study, an equal area based two-parameter logistic model estimation algorithm is proposed. Two theorems are given to prove that the results of the algorithm are equivalent to the results of fitting data by logistic model. Numerical results are presented to show the stability and accuracy of the algorithm.

  1. Further comments on sensitivities, parameter estimation, and sampling design in one-dimensional analysis of solute transport in porous media

    USGS Publications Warehouse

    Knopman, Debra S.; Voss, Clifford I.

    1988-01-01

    Sensitivities of solute concentration to parameters associated with first-order chemical decay, boundary conditions, initial conditions, and multilayer transport are examined in one-dimensional analytical models of transient solute transport in porous media. A sensitivity is a change in solute concentration resulting from a change in a model parameter. Sensitivity analysis is important because minimum information required in regression on chemical data for the estimation of model parameters by regression is expressed in terms of sensitivities. Nonlinear regression models of solute transport were tested on sets of noiseless observations from known models that exceeded the minimum sensitivity information requirements. Results demonstrate that the regression models consistently converged to the correct parameters when the initial sets of parameter values substantially deviated from the correct parameters. On the basis of the sensitivity analysis, several statements may be made about design of sampling for parameter estimation for the models examined: (1) estimation of parameters associated with solute transport in the individual layers of a multilayer system is possible even when solute concentrations in the individual layers are mixed in an observation well; (2) when estimating parameters in a decaying upstream boundary condition, observations are best made late in the passage of the front near a time chosen by adding the inverse of an hypothesized value of the source decay parameter to the estimated mean travel time at a given downstream location; (3) estimation of a first-order chemical decay parameter requires observations to be made late in the passage of the front, preferably near a location corresponding to a travel time of √2 times the half-life of the solute; and (4) estimation of a parameter relating to spatial variability in an initial condition requires observations to be made early in time relative to passage of the solute front.

  2. View Estimation Based on Value System

    NASA Astrophysics Data System (ADS)

    Takahashi, Yasutake; Shimada, Kouki; Asada, Minoru

    Estimation of a caregiver's view is one of the most important capabilities for a child to understand the behavior demonstrated by the caregiver, that is, to infer the intention of behavior and/or to learn the observed behavior efficiently. We hypothesize that the child develops this ability in the same way as behavior learning motivated by an intrinsic reward, that is, he/she updates the model of the estimated view of his/her own during the behavior imitated from the observation of the behavior demonstrated by the caregiver based on minimizing the estimation error of the reward during the behavior. From this view, this paper shows a method for acquiring such a capability based on a value system from which values can be obtained by reinforcement learning. The parameters of the view estimation are updated based on the temporal difference error (hereafter TD error: estimation error of the state value), analogous to the way such that the parameters of the state value of the behavior are updated based on the TD error. Experiments with simple humanoid robots show the validity of the method, and the developmental process parallel to young children's estimation of its own view during the imitation of the observed behavior of the caregiver is discussed.

  3. 40 CFR 98.205 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emission... substitute data value for the missing parameter will be used in the calculations as specified in paragraph (b...

  4. 40 CFR 98.415 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... Procedures for estimating missing data. (a) A complete record of all measured parameters used in the GHG... unavailable (e.g., if a meter malfunctions), a substitute data value for the missing parameter shall be used...

  5. 40 CFR 98.415 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... Procedures for estimating missing data. (a) A complete record of all measured parameters used in the GHG... unavailable (e.g., if a meter malfunctions), a substitute data value for the missing parameter shall be used...

  6. 40 CFR 98.205 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emission... substitute data value for the missing parameter will be used in the calculations as specified in paragraph (b...

  7. 40 CFR 98.205 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emission... substitute data value for the missing parameter will be used in the calculations as specified in paragraph (b...

  8. 40 CFR 98.205 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... estimating missing data. (a) A complete record of all measured parameters used in the GHG emission... substitute data value for the missing parameter will be used in the calculations as specified in paragraph (b...

  9. 40 CFR 98.415 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... Procedures for estimating missing data. (a) A complete record of all measured parameters used in the GHG... unavailable (e.g., if a meter malfunctions), a substitute data value for the missing parameter shall be used...

  10. 40 CFR 98.415 - Procedures for estimating missing data.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Procedures for estimating missing data... Procedures for estimating missing data. (a) A complete record of all measured parameters used in the GHG... unavailable (e.g., if a meter malfunctions), a substitute data value for the missing parameter shall be used...

  11. 40 CFR 98.415 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... Procedures for estimating missing data. (a) A complete record of all measured parameters used in the GHG... unavailable (e.g., if a meter malfunctions), a substitute data value for the missing parameter shall be used...

  12. A Modified Cramer-von Mises and Anderson-Darling Test for the Weibull Distribution with Unknown Location and Scale Parameters.

    DTIC Science & Technology

    1981-12-01

    preventing the generation of 16 6 negative location estimators. Because of the invariant pro- perty of the EDF statistics, this transformation will...likelihood. If the parameter estimation method developed by Harter and Moore is used, care must be taken to prevent the location estimators from being...vs A 2 Critical Values, Level-.Ol, n-30 128 , 0 6N m m • w - APPENDIX E Computer Prgrams 129 Program to Calculate the Cramer-von Mises Critical Values

  13. Evaluation of severe accident risks: Quantification of major input parameters: MAACS (MELCOR Accident Consequence Code System) input

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sprung, J.L.; Jow, H-N; Rollstin, J.A.

    1990-12-01

    Estimation of offsite accident consequences is the customary final step in a probabilistic assessment of the risks of severe nuclear reactor accidents. Recently, the Nuclear Regulatory Commission reassessed the risks of severe accidents at five US power reactors (NUREG-1150). Offsite accident consequences for NUREG-1150 source terms were estimated using the MELCOR Accident Consequence Code System (MACCS). Before these calculations were performed, most MACCS input parameters were reviewed, and for each parameter reviewed, a best-estimate value was recommended. This report presents the results of these reviews. Specifically, recommended values and the basis for their selection are presented for MACCS atmospheric andmore » biospheric transport, emergency response, food pathway, and economic input parameters. Dose conversion factors and health effect parameters are not reviewed in this report. 134 refs., 15 figs., 110 tabs.« less

  14. NWP model forecast skill optimization via closure parameter variations

    NASA Astrophysics Data System (ADS)

    Järvinen, H.; Ollinaho, P.; Laine, M.; Solonen, A.; Haario, H.

    2012-04-01

    We present results of a novel approach to tune predictive skill of numerical weather prediction (NWP) models. These models contain tunable parameters which appear in parameterizations schemes of sub-grid scale physical processes. The current practice is to specify manually the numerical parameter values, based on expert knowledge. We developed recently a concept and method (QJRMS 2011) for on-line estimation of the NWP model parameters via closure parameter variations. The method called EPPES ("Ensemble prediction and parameter estimation system") utilizes ensemble prediction infra-structure for parameter estimation in a very cost-effective way: practically no new computations are introduced. The approach provides an algorithmic decision making tool for model parameter optimization in operational NWP. In EPPES, statistical inference about the NWP model tunable parameters is made by (i) generating an ensemble of predictions so that each member uses different model parameter values, drawn from a proposal distribution, and (ii) feeding-back the relative merits of the parameter values to the proposal distribution, based on evaluation of a suitable likelihood function against verifying observations. In this presentation, the method is first illustrated in low-order numerical tests using a stochastic version of the Lorenz-95 model which effectively emulates the principal features of ensemble prediction systems. The EPPES method correctly detects the unknown and wrongly specified parameters values, and leads to an improved forecast skill. Second, results with an ensemble prediction system emulator, based on the ECHAM5 atmospheric GCM show that the model tuning capability of EPPES scales up to realistic models and ensemble prediction systems. Finally, preliminary results of EPPES in the context of ECMWF forecasting system are presented.

  15. Performance comparison of first-order conditional estimation with interaction and Bayesian estimation methods for estimating the population parameters and its distribution from data sets with a low number of subjects.

    PubMed

    Pradhan, Sudeep; Song, Byungjeong; Lee, Jaeyeon; Chae, Jung-Woo; Kim, Kyung Im; Back, Hyun-Moon; Han, Nayoung; Kwon, Kwang-Il; Yun, Hwi-Yeol

    2017-12-01

    Exploratory preclinical, as well as clinical trials, may involve a small number of patients, making it difficult to calculate and analyze the pharmacokinetic (PK) parameters, especially if the PK parameters show very high inter-individual variability (IIV). In this study, the performance of a classical first-order conditional estimation with interaction (FOCE-I) and expectation maximization (EM)-based Markov chain Monte Carlo Bayesian (BAYES) estimation methods were compared for estimating the population parameters and its distribution from data sets having a low number of subjects. In this study, 100 data sets were simulated with eight sampling points for each subject and with six different levels of IIV (5%, 10%, 20%, 30%, 50%, and 80%) in their PK parameter distribution. A stochastic simulation and estimation (SSE) study was performed to simultaneously simulate data sets and estimate the parameters using four different methods: FOCE-I only, BAYES(C) (FOCE-I and BAYES composite method), BAYES(F) (BAYES with all true initial parameters and fixed ω 2 ), and BAYES only. Relative root mean squared error (rRMSE) and relative estimation error (REE) were used to analyze the differences between true and estimated values. A case study was performed with a clinical data of theophylline available in NONMEM distribution media. NONMEM software assisted by Pirana, PsN, and Xpose was used to estimate population PK parameters, and R program was used to analyze and plot the results. The rRMSE and REE values of all parameter (fixed effect and random effect) estimates showed that all four methods performed equally at the lower IIV levels, while the FOCE-I method performed better than other EM-based methods at higher IIV levels (greater than 30%). In general, estimates of random-effect parameters showed significant bias and imprecision, irrespective of the estimation method used and the level of IIV. Similar performance of the estimation methods was observed with theophylline dataset. The classical FOCE-I method appeared to estimate the PK parameters more reliably than the BAYES method when using a simple model and data containing only a few subjects. EM-based estimation methods can be considered for adapting to the specific needs of a modeling project at later steps of modeling.

  16. A simulation of water pollution model parameter estimation

    NASA Technical Reports Server (NTRS)

    Kibler, J. F.

    1976-01-01

    A parameter estimation procedure for a water pollution transport model is elaborated. A two-dimensional instantaneous-release shear-diffusion model serves as representative of a simple transport process. Pollution concentration levels are arrived at via modeling of a remote-sensing system. The remote-sensed data are simulated by adding Gaussian noise to the concentration level values generated via the transport model. Model parameters are estimated from the simulated data using a least-squares batch processor. Resolution, sensor array size, and number and location of sensor readings can be found from the accuracies of the parameter estimates.

  17. Characteristics and Impact Factors of Parameter Alpha in the Nonlinear Advection-Aridity Method for Estimating Evapotranspiration at Interannual Scale in the Loess Plateau

    NASA Astrophysics Data System (ADS)

    Zhou, H.; Liu, W.; Ning, T.

    2017-12-01

    Land surface actual evapotranspiration plays a key role in the global water and energy cycles. Accurate estimation of evapotranspiration is crucial for understanding the interactions between the land surface and the atmosphere, as well as for managing water resources. The nonlinear advection-aridity approach was formulated by Brutsaert to estimate actual evapotranspiration in 2015. Subsequently, this approach has been verified, applied and developed by many scholars. The estimation, impact factors and correlation analysis of the parameter alpha (αe) of this approach has become important aspects of the research. According to the principle of this approach, the potential evapotranspiration (ETpo) (taking αe as 1) and the apparent potential evapotranspiration (ETpm) were calculated using the meteorological data of 123 sites of the Loess Plateau and its surrounding areas. Then the mean spatial values of precipitation (P), ETpm and ETpo for 13 catchments were obtained by a CoKriging interpolation algorithm. Based on the runoff data of the 13 catchments, actual evapotranspiration was calculated using the catchment water balance equation at the hydrological year scale (May to April of the following year) by ignoring the change of catchment water storage. Thus, the parameter was estimated, and its relationships with P, ETpm and aridity index (ETpm/P) were further analyzed. The results showed that the general range of annual parameter value was 0.385-1.085, with an average value of 0.751 and a standard deviation of 0.113. The mean annual parameter αe value showed different spatial characteristics, with lower values in northern and higher values in southern. The annual scale parameter linearly related with annual P (R2=0.89) and ETpm (R2=0.49), while it exhibited a power function relationship with the aridity index (R2=0.83). Considering the ETpm is a variable in the nonlinear advection-aridity approach in which its effect has been incorporated, the relationship of precipitation and parameter (αe=1.0×10-3*P+0.301) was developed. The value of αe in this study is lower than those in the published literature. The reason is unclear at this point and yet need further investigation. The preliminary application of the nonlinear advection-aridity approach in the Loess Plateau has shown promising results.

  18. ProUCL Version 4.0 Technical Guide

    EPA Science Inventory

    Statistical inference, including both estimation and hypotheses testing approaches, is routinely used to: estimate environmental parameters of interest, such as exposure point concentration (EPC) terms, not-to-exceed values, and background level threshold values (BTVs) for contam...

  19. Disentangling Disadvantage: Can We Distinguish Good Teaching from Classroom Composition?

    PubMed

    Zamarro, Gema; Engberg, John; Saavedra, Juan Esteban; Steele, Jennifer

    This paper investigates the use of teacher value-added estimates to assess the distribution of effective teaching across students of varying socioeconomic disadvantage in the presence of classroom composition effects. We examine, via simulations, how accurately commonly-used teacher-value added estimators recover the rank correlation between true and estimated teacher effects and a parameter representing the distribution of effective teaching. We consider various scenarios of teacher assignment, within-teacher variability in classroom composition, importance of classroom composition effects, and presence of student unobserved heterogeneity. No single model recovers without bias estimates of the distribution parameter in all the scenarios we consider. Models that rank teacher effectiveness most accurately do not necessarily recover distribution parameter estimates with less bias. Since true teacher sorting in real data is seldom known, we recommend that analysts incorporate contextual information into their decisions about model choice and we offer some guidance on how to do so.

  20. Effects of control inputs on the estimation of stability and control parameters of a light airplane

    NASA Technical Reports Server (NTRS)

    Cannaday, R. L.; Suit, W. T.

    1977-01-01

    The maximum likelihood parameter estimation technique was used to determine the values of stability and control derivatives from flight test data for a low-wing, single-engine, light airplane. Several input forms were used during the tests to investigate the consistency of parameter estimates as it relates to inputs. These consistencies were compared by using the ensemble variance and estimated Cramer-Rao lower bound. In addition, the relationship between inputs and parameter correlations was investigated. Results from the stabilator inputs are inconclusive but the sequence of rudder input followed by aileron input or aileron followed by rudder gave more consistent estimates than did rudder or ailerons individually. Also, square-wave inputs appeared to provide slightly improved consistency in the parameter estimates when compared to sine-wave inputs.

  1. An Optimal Orthogonal Decomposition Method for Kalman Filter-Based Turbofan Engine Thrust Estimation

    NASA Technical Reports Server (NTRS)

    Litt, Jonathan S.

    2007-01-01

    A new linear point design technique is presented for the determination of tuning parameters that enable the optimal estimation of unmeasured engine outputs, such as thrust. The engine's performance is affected by its level of degradation, generally described in terms of unmeasurable health parameters related to each major engine component. Accurate thrust reconstruction depends on knowledge of these health parameters, but there are usually too few sensors to be able to estimate their values. In this new technique, a set of tuning parameters is determined that accounts for degradation by representing the overall effect of the larger set of health parameters as closely as possible in a least squares sense. The technique takes advantage of the properties of the singular value decomposition of a matrix to generate a tuning parameter vector of low enough dimension that it can be estimated by a Kalman filter. A concise design procedure to generate a tuning vector that specifically takes into account the variables of interest is presented. An example demonstrates the tuning parameters ability to facilitate matching of both measured and unmeasured engine outputs, as well as state variables. Additional properties of the formulation are shown to lend themselves well to diagnostics.

  2. An Optimal Orthogonal Decomposition Method for Kalman Filter-Based Turbofan Engine Thrust Estimation

    NASA Technical Reports Server (NTRS)

    Litt, Jonathan S.

    2007-01-01

    A new linear point design technique is presented for the determination of tuning parameters that enable the optimal estimation of unmeasured engine outputs, such as thrust. The engine s performance is affected by its level of degradation, generally described in terms of unmeasurable health parameters related to each major engine component. Accurate thrust reconstruction depends on knowledge of these health parameters, but there are usually too few sensors to be able to estimate their values. In this new technique, a set of tuning parameters is determined that accounts for degradation by representing the overall effect of the larger set of health parameters as closely as possible in a least-squares sense. The technique takes advantage of the properties of the singular value decomposition of a matrix to generate a tuning parameter vector of low enough dimension that it can be estimated by a Kalman filter. A concise design procedure to generate a tuning vector that specifically takes into account the variables of interest is presented. An example demonstrates the tuning parameters ability to facilitate matching of both measured and unmeasured engine outputs, as well as state variables. Additional properties of the formulation are shown to lend themselves well to diagnostics.

  3. An Optimal Orthogonal Decomposition Method for Kalman Filter-Based Turbofan Engine Thrust Estimation

    NASA Technical Reports Server (NTRS)

    Litt, Jonathan S.

    2005-01-01

    A new linear point design technique is presented for the determination of tuning parameters that enable the optimal estimation of unmeasured engine outputs such as thrust. The engine s performance is affected by its level of degradation, generally described in terms of unmeasurable health parameters related to each major engine component. Accurate thrust reconstruction depends upon knowledge of these health parameters, but there are usually too few sensors to be able to estimate their values. In this new technique, a set of tuning parameters is determined which accounts for degradation by representing the overall effect of the larger set of health parameters as closely as possible in a least squares sense. The technique takes advantage of the properties of the singular value decomposition of a matrix to generate a tuning parameter vector of low enough dimension that it can be estimated by a Kalman filter. A concise design procedure to generate a tuning vector that specifically takes into account the variables of interest is presented. An example demonstrates the tuning parameters ability to facilitate matching of both measured and unmeasured engine outputs, as well as state variables. Additional properties of the formulation are shown to lend themselves well to diagnostics.

  4. Behavior of sensitivities in the one-dimensional advection-dispersion equation: Implications for parameter estimation and sampling design

    USGS Publications Warehouse

    Knopman, Debra S.; Voss, Clifford I.

    1987-01-01

    The spatial and temporal variability of sensitivities has a significant impact on parameter estimation and sampling design for studies of solute transport in porous media. Physical insight into the behavior of sensitivities is offered through an analysis of analytically derived sensitivities for the one-dimensional form of the advection-dispersion equation. When parameters are estimated in regression models of one-dimensional transport, the spatial and temporal variability in sensitivities influences variance and covariance of parameter estimates. Several principles account for the observed influence of sensitivities on parameter uncertainty. (1) Information about a physical parameter may be most accurately gained at points in space and time with a high sensitivity to the parameter. (2) As the distance of observation points from the upstream boundary increases, maximum sensitivity to velocity during passage of the solute front increases and the consequent estimate of velocity tends to have lower variance. (3) The frequency of sampling must be “in phase” with the S shape of the dispersion sensitivity curve to yield the most information on dispersion. (4) The sensitivity to the dispersion coefficient is usually at least an order of magnitude less than the sensitivity to velocity. (5) The assumed probability distribution of random error in observations of solute concentration determines the form of the sensitivities. (6) If variance in random error in observations is large, trends in sensitivities of observation points may be obscured by noise and thus have limited value in predicting variance in parameter estimates among designs. (7) Designs that minimize the variance of one parameter may not necessarily minimize the variance of other parameters. (8) The time and space interval over which an observation point is sensitive to a given parameter depends on the actual values of the parameters in the underlying physical system.

  5. Hydrological model parameterization using NDVI values to account for the effects of land-cover change on the rainfall-runoff response

    USDA-ARS?s Scientific Manuscript database

    Classic rainfall-runoff models usually use historical data to estimate model parameters and mean values of parameters are considered for predictions. However, due to climate changes and human effects, the parameters of model change temporally. To overcome this problem, Normalized Difference Vegetati...

  6. Approximate, computationally efficient online learning in Bayesian spiking neurons.

    PubMed

    Kuhlmann, Levin; Hauser-Raspe, Michael; Manton, Jonathan H; Grayden, David B; Tapson, Jonathan; van Schaik, André

    2014-03-01

    Bayesian spiking neurons (BSNs) provide a probabilistic interpretation of how neurons perform inference and learning. Online learning in BSNs typically involves parameter estimation based on maximum-likelihood expectation-maximization (ML-EM) which is computationally slow and limits the potential of studying networks of BSNs. An online learning algorithm, fast learning (FL), is presented that is more computationally efficient than the benchmark ML-EM for a fixed number of time steps as the number of inputs to a BSN increases (e.g., 16.5 times faster run times for 20 inputs). Although ML-EM appears to converge 2.0 to 3.6 times faster than FL, the computational cost of ML-EM means that ML-EM takes longer to simulate to convergence than FL. FL also provides reasonable convergence performance that is robust to initialization of parameter estimates that are far from the true parameter values. However, parameter estimation depends on the range of true parameter values. Nevertheless, for a physiologically meaningful range of parameter values, FL gives very good average estimation accuracy, despite its approximate nature. The FL algorithm therefore provides an efficient tool, complementary to ML-EM, for exploring BSN networks in more detail in order to better understand their biological relevance. Moreover, the simplicity of the FL algorithm means it can be easily implemented in neuromorphic VLSI such that one can take advantage of the energy-efficient spike coding of BSNs.

  7. Censored Hurdle Negative Binomial Regression (Case Study: Neonatorum Tetanus Case in Indonesia)

    NASA Astrophysics Data System (ADS)

    Yuli Rusdiana, Riza; Zain, Ismaini; Wulan Purnami, Santi

    2017-06-01

    Hurdle negative binomial model regression is a method that can be used for discreate dependent variable, excess zero and under- and overdispersion. It uses two parts approach. The first part estimates zero elements from dependent variable is zero hurdle model and the second part estimates not zero elements (non-negative integer) from dependent variable is called truncated negative binomial models. The discrete dependent variable in such cases is censored for some values. The type of censor that will be studied in this research is right censored. This study aims to obtain the parameter estimator hurdle negative binomial regression for right censored dependent variable. In the assessment of parameter estimation methods used Maximum Likelihood Estimator (MLE). Hurdle negative binomial model regression for right censored dependent variable is applied on the number of neonatorum tetanus cases in Indonesia. The type data is count data which contains zero values in some observations and other variety value. This study also aims to obtain the parameter estimator and test statistic censored hurdle negative binomial model. Based on the regression results, the factors that influence neonatorum tetanus case in Indonesia is the percentage of baby health care coverage and neonatal visits.

  8. Simultaneous Estimation of Microphysical Parameters and Atmospheric State Variables With Radar Data and Ensemble Square-root Kalman Filter

    NASA Astrophysics Data System (ADS)

    Tong, M.; Xue, M.

    2006-12-01

    An important source of model error for convective-scale data assimilation and prediction is microphysical parameterization. This study investigates the possibility of estimating up to five fundamental microphysical parameters, which are closely involved in the definition of drop size distribution of microphysical species in a commonly used single-moment ice microphysics scheme, using radar observations and the ensemble Kalman filter method. The five parameters include the intercept parameters for rain, snow and hail/graupel, and the bulk densities of hail/graupel and snow. Parameter sensitivity and identifiability are first examined. The ensemble square-root Kalman filter (EnSRF) is employed for simultaneous state and parameter estimation. OSS experiments are performed for a model-simulated supercell storm, in which the five microphysical parameters are estimated individually or in different combinations starting from different initial guesses. When error exists in only one of the microphysical parameters, the parameter can be successfully estimated without exception. The estimation of multiple parameters is found to be less robust, with end results of estimation being sensitive to the realization of the initial parameter perturbation. This is believed to be because of the reduced parameter identifiability and the existence of non-unique solutions. The results of state estimation are, however, always improved when simultaneous parameter estimation is performed, even when the estimated parameters values are not accurate.

  9. Estimation of environment-related properties of chemicals for design of sustainable processes: development of group-contribution+ (GC+) property models and uncertainty analysis.

    PubMed

    Hukkerikar, Amol Shivajirao; Kalakul, Sawitree; Sarup, Bent; Young, Douglas M; Sin, Gürkan; Gani, Rafiqul

    2012-11-26

    The aim of this work is to develop group-contribution(+) (GC(+)) method (combined group-contribution (GC) method and atom connectivity index (CI) method) based property models to provide reliable estimations of environment-related properties of organic chemicals together with uncertainties of estimated property values. For this purpose, a systematic methodology for property modeling and uncertainty analysis is used. The methodology includes a parameter estimation step to determine parameters of property models and an uncertainty analysis step to establish statistical information about the quality of parameter estimation, such as the parameter covariance, the standard errors in predicted properties, and the confidence intervals. For parameter estimation, large data sets of experimentally measured property values of a wide range of chemicals (hydrocarbons, oxygenated chemicals, nitrogenated chemicals, poly functional chemicals, etc.) taken from the database of the US Environmental Protection Agency (EPA) and from the database of USEtox is used. For property modeling and uncertainty analysis, the Marrero and Gani GC method and atom connectivity index method have been considered. In total, 22 environment-related properties, which include the fathead minnow 96-h LC(50), Daphnia magna 48-h LC(50), oral rat LD(50), aqueous solubility, bioconcentration factor, permissible exposure limit (OSHA-TWA), photochemical oxidation potential, global warming potential, ozone depletion potential, acidification potential, emission to urban air (carcinogenic and noncarcinogenic), emission to continental rural air (carcinogenic and noncarcinogenic), emission to continental fresh water (carcinogenic and noncarcinogenic), emission to continental seawater (carcinogenic and noncarcinogenic), emission to continental natural soil (carcinogenic and noncarcinogenic), and emission to continental agricultural soil (carcinogenic and noncarcinogenic) have been modeled and analyzed. The application of the developed property models for the estimation of environment-related properties and uncertainties of the estimated property values is highlighted through an illustrative example. The developed property models provide reliable estimates of environment-related properties needed to perform process synthesis, design, and analysis of sustainable chemical processes and allow one to evaluate the effect of uncertainties of estimated property values on the calculated performance of processes giving useful insights into quality and reliability of the design of sustainable processes.

  10. MODFLOW-2000, the U.S. Geological Survey modular ground-water model; user guide to the observation, sensitivity, and parameter-estimation processes and three post-processing programs

    USGS Publications Warehouse

    Hill, Mary C.; Banta, E.R.; Harbaugh, A.W.; Anderman, E.R.

    2000-01-01

    This report documents the Observation, Sensitivity, and Parameter-Estimation Processes of the ground-water modeling computer program MODFLOW-2000. The Observation Process generates model-calculated values for comparison with measured, or observed, quantities. A variety of statistics is calculated to quantify this comparison, including a weighted least-squares objective function. In addition, a number of files are produced that can be used to compare the values graphically. The Sensitivity Process calculates the sensitivity of hydraulic heads throughout the model with respect to specified parameters using the accurate sensitivity-equation method. These are called grid sensitivities. If the Observation Process is active, it uses the grid sensitivities to calculate sensitivities for the simulated values associated with the observations. These are called observation sensitivities. Observation sensitivities are used to calculate a number of statistics that can be used (1) to diagnose inadequate data, (2) to identify parameters that probably cannot be estimated by regression using the available observations, and (3) to evaluate the utility of proposed new data. The Parameter-Estimation Process uses a modified Gauss-Newton method to adjust values of user-selected input parameters in an iterative procedure to minimize the value of the weighted least-squares objective function. Statistics produced by the Parameter-Estimation Process can be used to evaluate estimated parameter values; statistics produced by the Observation Process and post-processing program RESAN-2000 can be used to evaluate how accurately the model represents the actual processes; statistics produced by post-processing program YCINT-2000 can be used to quantify the uncertainty of model simulated values. Parameters are defined in the Ground-Water Flow Process input files and can be used to calculate most model inputs, such as: for explicitly defined model layers, horizontal hydraulic conductivity, horizontal anisotropy, vertical hydraulic conductivity or vertical anisotropy, specific storage, and specific yield; and, for implicitly represented layers, vertical hydraulic conductivity. In addition, parameters can be defined to calculate the hydraulic conductance of the River, General-Head Boundary, and Drain Packages; areal recharge rates of the Recharge Package; maximum evapotranspiration of the Evapotranspiration Package; pumpage or the rate of flow at defined-flux boundaries of the Well Package; and the hydraulic head at constant-head boundaries. The spatial variation of model inputs produced using defined parameters is very flexible, including interpolated distributions that require the summation of contributions from different parameters. Observations can include measured hydraulic heads or temporal changes in hydraulic heads, measured gains and losses along head-dependent boundaries (such as streams), flows through constant-head boundaries, and advective transport through the system, which generally would be inferred from measured concentrations. MODFLOW-2000 is intended for use on any computer operating system. The program consists of algorithms programmed in Fortran 90, which efficiently performs numerical calculations and is fully compatible with the newer Fortran 95. The code is easily modified to be compatible with FORTRAN 77. Coordination for multiple processors is accommodated using Message Passing Interface (MPI) commands. The program is designed in a modular fashion that is intended to support inclusion of new capabilities.

  11. Estimation of regression laws for ground motion parameters using as case of study the Amatrice earthquake

    NASA Astrophysics Data System (ADS)

    Tiberi, Lara; Costa, Giovanni

    2017-04-01

    The possibility to directly associate the damages to the ground motion parameters is always a great challenge, in particular for civil protections. Indeed a ground motion parameter, estimated in near real time that can express the damages occurred after an earthquake, is fundamental to arrange the first assistance after an event. The aim of this work is to contribute to the estimation of the ground motion parameter that better describes the observed intensity, immediately after an event. This can be done calculating for each ground motion parameter estimated in a near real time mode a regression law which correlates the above-mentioned parameter to the observed macro-seismic intensity. This estimation is done collecting high quality accelerometric data in near field, filtering them at different frequency steps. The regression laws are calculated using two different techniques: the non linear least-squares (NLLS) Marquardt-Levenberg algorithm and the orthogonal distance methodology (ODR). The limits of the first methodology are the needed of initial values for the parameters a and b (set 1.0 in this study), and the constraint that the independent variable must be known with greater accuracy than the dependent variable. While the second algorithm is based on the estimation of the errors perpendicular to the line, rather than just vertically. The vertical errors are just the errors in the 'y' direction, so only for the dependent variable whereas the perpendicular errors take into account errors for both the variables, the dependent and the independent. This makes possible also to directly invert the relation, so the a and b values can be used also to express the gmps as function of I. For each law the standard deviation and R2 value are estimated in order to test the quality and the reliability of the found relation. The Amatrice earthquake of 24th August of 2016 is used as case of study to test the goodness of the calculated regression laws.

  12. Relative effects of survival and reproduction on the population dynamics of emperor geese

    USGS Publications Warehouse

    Schmutz, Joel A.; Rockwell, Robert F.; Petersen, Margaret R.

    1997-01-01

    Populations of emperor geese (Chen canagica) in Alaska declined sometime between the mid-1960s and the mid-1980s and have increased little since. To promote recovery of this species to former levels, managers need to know how much their perturbations of survival and/or reproduction would affect population growth rate (λ). We constructed an individual-based population model to evaluate the relative effect of altering mean values of various survival and reproductive parameters on λ and fall age structure (AS, defined as the proportion of juv), assuming additive rather than compensatory relations among parameters. Altering survival of adults had markedly greater relative effects on λ than did equally proportionate changes in either juvenile survival or reproductive parameters. We found the opposite pattern for relative effects on AS. Due to concerns about bias in the initial parameter estimates used in our model, we used 5 additional sets of parameter estimates with this model structure. We found that estimates of survival based on aerial survey data gathered each fall resulted in models that corresponded more closely to independent estimates of λ than did models that used mark-recapture estimates of survival. This disparity suggests that mark-recapture estimates of survival are biased low. To further explore how parameter estimates affected estimates of λ, we used values of survival and reproduction found in other goose species, and we examined the effect of an hypothesized correlation between an individual's clutch size and the subsequent survival of her young. The rank order of parameters in their relative effects on λ was consistent for all 6 parameter sets we examined. The observed variation in relative effects on λ among the 6 parameter sets is indicative of how relative effects on λ may vary among goose populations. With this knowledge of the relative effects of survival and reproductive parameters on λ, managers can make more informed decisions about which parameters to influence through management or to target for future study.

  13. Three-dimensional whole-brain perfusion quantification using pseudo-continuous arterial spin labeling MRI at multiple post-labeling delays: accounting for both arterial transit time and impulse response function.

    PubMed

    Qin, Qin; Huang, Alan J; Hua, Jun; Desmond, John E; Stevens, Robert D; van Zijl, Peter C M

    2014-02-01

    Measurement of the cerebral blood flow (CBF) with whole-brain coverage is challenging in terms of both acquisition and quantitative analysis. In order to fit arterial spin labeling-based perfusion kinetic curves, an empirical three-parameter model which characterizes the effective impulse response function (IRF) is introduced, which allows the determination of CBF, the arterial transit time (ATT) and T(1,eff). The accuracy and precision of the proposed model were compared with those of more complicated models with four or five parameters through Monte Carlo simulations. Pseudo-continuous arterial spin labeling images were acquired on a clinical 3-T scanner in 10 normal volunteers using a three-dimensional multi-shot gradient and spin echo scheme at multiple post-labeling delays to sample the kinetic curves. Voxel-wise fitting was performed using the three-parameter model and other models that contain two, four or five unknown parameters. For the two-parameter model, T(1,eff) values close to tissue and blood were assumed separately. Standard statistical analysis was conducted to compare these fitting models in various brain regions. The fitted results indicated that: (i) the estimated CBF values using the two-parameter model show appreciable dependence on the assumed T(1,eff) values; (ii) the proposed three-parameter model achieves the optimal balance between the goodness of fit and model complexity when compared among the models with explicit IRF fitting; (iii) both the two-parameter model using fixed blood T1 values for T(1,eff) and the three-parameter model provide reasonable fitting results. Using the proposed three-parameter model, the estimated CBF (46 ± 14 mL/100 g/min) and ATT (1.4 ± 0.3 s) values averaged from different brain regions are close to the literature reports; the estimated T(1,eff) values (1.9 ± 0.4 s) are higher than the tissue T1 values, possibly reflecting a contribution from the microvascular arterial blood compartment. Copyright © 2013 John Wiley & Sons, Ltd.

  14. A Comparative Study of Distribution System Parameter Estimation Methods

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sun, Yannan; Williams, Tess L.; Gourisetti, Sri Nikhil Gup

    2016-07-17

    In this paper, we compare two parameter estimation methods for distribution systems: residual sensitivity analysis and state-vector augmentation with a Kalman filter. These two methods were originally proposed for transmission systems, and are still the most commonly used methods for parameter estimation. Distribution systems have much lower measurement redundancy than transmission systems. Therefore, estimating parameters is much more difficult. To increase the robustness of parameter estimation, the two methods are applied with combined measurement snapshots (measurement sets taken at different points in time), so that the redundancy for computing the parameter values is increased. The advantages and disadvantages of bothmore » methods are discussed. The results of this paper show that state-vector augmentation is a better approach for parameter estimation in distribution systems. Simulation studies are done on a modified version of IEEE 13-Node Test Feeder with varying levels of measurement noise and non-zero error in the other system model parameters.« less

  15. Poster — Thur Eve — 44: Linearization of Compartmental Models for More Robust Estimates of Regional Hemodynamic, Metabolic and Functional Parameters using DCE-CT/PET Imaging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blais, AR; Dekaban, M; Lee, T-Y

    2014-08-15

    Quantitative analysis of dynamic positron emission tomography (PET) data usually involves minimizing a cost function with nonlinear regression, wherein the choice of starting parameter values and the presence of local minima affect the bias and variability of the estimated kinetic parameters. These nonlinear methods can also require lengthy computation time, making them unsuitable for use in clinical settings. Kinetic modeling of PET aims to estimate the rate parameter k{sub 3}, which is the binding affinity of the tracer to a biological process of interest and is highly susceptible to noise inherent in PET image acquisition. We have developed linearized kineticmore » models for kinetic analysis of dynamic contrast enhanced computed tomography (DCE-CT)/PET imaging, including a 2-compartment model for DCE-CT and a 3-compartment model for PET. Use of kinetic parameters estimated from DCE-CT can stabilize the kinetic analysis of dynamic PET data, allowing for more robust estimation of k{sub 3}. Furthermore, these linearized models are solved with a non-negative least squares algorithm and together they provide other advantages including: 1) only one possible solution and they do not require a choice of starting parameter values, 2) parameter estimates are comparable in accuracy to those from nonlinear models, 3) significantly reduced computational time. Our simulated data show that when blood volume and permeability are estimated with DCE-CT, the bias of k{sub 3} estimation with our linearized model is 1.97 ± 38.5% for 1,000 runs with a signal-to-noise ratio of 10. In summary, we have developed a computationally efficient technique for accurate estimation of k{sub 3} from noisy dynamic PET data.« less

  16. Posterior uncertainty of GEOS-5 L-band radiative transfer model parameters and brightness temperatures after calibration with SMOS observations

    NASA Astrophysics Data System (ADS)

    De Lannoy, G. J.; Reichle, R. H.; Vrugt, J. A.

    2012-12-01

    Simulated L-band (1.4 GHz) brightness temperatures are very sensitive to the values of the parameters in the radiative transfer model (RTM). We assess the optimum RTM parameter values and their (posterior) uncertainty in the Goddard Earth Observing System (GEOS-5) land surface model using observations of multi-angular brightness temperature over North America from the Soil Moisture Ocean Salinity (SMOS) mission. Two different parameter estimation methods are being compared: (i) a particle swarm optimization (PSO) approach, and (ii) an MCMC simulation procedure using the differential evolution adaptive Metropolis (DREAM) algorithm. Our results demonstrate that both methods provide similar "optimal" parameter values. Yet, DREAM exhibits better convergence properties, resulting in a reduced spread of the posterior ensemble. The posterior parameter distributions derived with both methods are used for predictive uncertainty estimation of brightness temperature. This presentation will highlight our model-data synthesis framework and summarize our initial findings.

  17. Obtaining parsimonious hydraulic conductivity fields using head and transport observations: A Bayesian geostatistical parameter estimation approach

    NASA Astrophysics Data System (ADS)

    Fienen, M.; Hunt, R.; Krabbenhoft, D.; Clemo, T.

    2009-08-01

    Flow path delineation is a valuable tool for interpreting the subsurface hydrogeochemical environment. Different types of data, such as groundwater flow and transport, inform different aspects of hydrogeologic parameter values (hydraulic conductivity in this case) which, in turn, determine flow paths. This work combines flow and transport information to estimate a unified set of hydrogeologic parameters using the Bayesian geostatistical inverse approach. Parameter flexibility is allowed by using a highly parameterized approach with the level of complexity informed by the data. Despite the effort to adhere to the ideal of minimal a priori structure imposed on the problem, extreme contrasts in parameters can result in the need to censor correlation across hydrostratigraphic bounding surfaces. These partitions segregate parameters into facies associations. With an iterative approach in which partitions are based on inspection of initial estimates, flow path interpretation is progressively refined through the inclusion of more types of data. Head observations, stable oxygen isotopes (18O/16O ratios), and tritium are all used to progressively refine flow path delineation on an isthmus between two lakes in the Trout Lake watershed, northern Wisconsin, United States. Despite allowing significant parameter freedom by estimating many distributed parameter values, a smooth field is obtained.

  18. Obtaining parsimonious hydraulic conductivity fields using head and transport observations: A Bayesian geostatistical parameter estimation approach

    USGS Publications Warehouse

    Fienen, M.; Hunt, R.; Krabbenhoft, D.; Clemo, T.

    2009-01-01

    Flow path delineation is a valuable tool for interpreting the subsurface hydrogeochemical environment. Different types of data, such as groundwater flow and transport, inform different aspects of hydrogeologic parameter values (hydraulic conductivity in this case) which, in turn, determine flow paths. This work combines flow and transport information to estimate a unified set of hydrogeologic parameters using the Bayesian geostatistical inverse approach. Parameter flexibility is allowed by using a highly parameterized approach with the level of complexity informed by the data. Despite the effort to adhere to the ideal of minimal a priori structure imposed on the problem, extreme contrasts in parameters can result in the need to censor correlation across hydrostratigraphic bounding surfaces. These partitions segregate parameters into facies associations. With an iterative approach in which partitions are based on inspection of initial estimates, flow path interpretation is progressively refined through the inclusion of more types of data. Head observations, stable oxygen isotopes (18O/16O ratios), and tritium are all used to progressively refine flow path delineation on an isthmus between two lakes in the Trout Lake watershed, northern Wisconsin, United States. Despite allowing significant parameter freedom by estimating many distributed parameter values, a smooth field is obtained.

  19. A technique for estimating time of concentration and storage coefficient values for Illinois streams

    USGS Publications Warehouse

    Graf, Julia B.; Garklavs, George; Oberg, Kevin A.

    1982-01-01

    Values of the unit hydrograph parameters time of concentration (TC) and storage coefficient (R) can be estimated for streams in Illinois by a two-step technique developed from data for 98 gaged basins in the State. The sum of TC and R is related to stream length (L) and main channel slope (S) by the relation (TC + R)e = 35.2L0.39S-0.78. The variable R/(TC + R) is not significantly correlated with drainage area, slope, or length, but does exhibit a regional trend. Regional values of R/(TC + R) are used with the computed values of (TC + R)e to solve for estimated values of time of concentration (TCe) and storage coefficient (Re). The use of the variable R/(TC + R) is thought to account for variations in unit hydrograph parameters caused by physiographic variables such as basin topography, flood-plain development, and basin storage characteristics. (USGS)

  20. Parameters effective on estimating a nonstationary mixed-phase wavelet using cumulant matching approach

    NASA Astrophysics Data System (ADS)

    Vosoughi, Ehsan; Javaherian, Abdolrahim

    2018-01-01

    Seismic inversion is a process performed to remove the effects of propagated wavelets in order to recover the acoustic impedance. To obtain valid velocity and density values related to subsurface layers through the inversion process, it is highly essential to perform reliable wavelet estimation such as cumulant matching approach. For this purpose, the seismic data were windowed in this work in such a way that two consecutive windows were only one sample apart. Also, we did not consider any fixed wavelet for any window and let the phase of each wavelet rotate in each sample in the window. Comparing the fourth order cumulant of the whitened trace and fourth-order moment of the all-pass operator in each window generated a cost function that should be minimized with a non-linear optimization method. In this regard, parameters effective on the estimation of the nonstationary mixed-phase wavelets were tested over the created nonstationary seismic trace at 0.82 s and 1.6 s. Besides, we compared the consequences of each parameter on estimated wavelets at two mentioned times. The parameters studied in this work are window length, taper type, the number of iteration, signal-to-noise ratio, bandwidth to central frequency ratio, and Q factor. The results show that applying the optimum values of the effective parameters, the average correlation of the estimated mixed-phase wavelets with the original ones is about 87%. Moreover, the effectiveness of the proposed approach was examined on a synthetic nonstationary seismic section with variable Q factor values alongside the time and offset axis. Eventually, the cumulant matching method was applied on a cross line of the migrated data from a 3D data set of an oilfield in the Persian Gulf. Also, the effect of the wrong Q estimation on the estimated mixed-phase wavelet was considered on the real data set. It is concluded that the accuracy of the estimated wavelet relied on the estimated Q and more than 10% error in the estimated value of Q is acceptable. Eventually, an 88% correlation was found between the estimated mixed-phase wavelets and the original ones for three horizons. The estimated wavelets applied to the data and the result of deconvolution processes was presented.

  1. Inverse estimation of parameters for an estuarine eutrophication model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shen, J.; Kuo, A.Y.

    1996-11-01

    An inverse model of an estuarine eutrophication model with eight state variables is developed. It provides a framework to estimate parameter values of the eutrophication model by assimilation of concentration data of these state variables. The inverse model using the variational technique in conjunction with a vertical two-dimensional eutrophication model is general enough to be applicable to aid model calibration. The formulation is illustrated by conducting a series of numerical experiments for the tidal Rappahannock River, a western shore tributary of the Chesapeake Bay. The numerical experiments of short-period model simulations with different hypothetical data sets and long-period model simulationsmore » with limited hypothetical data sets demonstrated that the inverse model can be satisfactorily used to estimate parameter values of the eutrophication model. The experiments also showed that the inverse model is useful to address some important questions, such as uniqueness of the parameter estimation and data requirements for model calibration. Because of the complexity of the eutrophication system, degrading of speed of convergence may occur. Two major factors which cause degradation of speed of convergence are cross effects among parameters and the multiple scales involved in the parameter system.« less

  2. Empirical Bayes estimation of proportions with application to cowbird parasitism rates

    USGS Publications Warehouse

    Link, W.A.; Hahn, D.C.

    1996-01-01

    Bayesian models provide a structure for studying collections of parameters such as are considered in the investigation of communities, ecosystems, and landscapes. This structure allows for improved estimation of individual parameters, by considering them in the context of a group of related parameters. Individual estimates are differentially adjusted toward an overall mean, with the magnitude of their adjustment based on their precision. Consequently, Bayesian estimation allows for a more credible identification of extreme values in a collection of estimates. Bayesian models regard individual parameters as values sampled from a specified probability distribution, called a prior. The requirement that the prior be known is often regarded as an unattractive feature of Bayesian analysis and may be the reason why Bayesian analyses are not frequently applied in ecological studies. Empirical Bayes methods provide an alternative approach that incorporates the structural advantages of Bayesian models while requiring a less stringent specification of prior knowledge. Rather than requiring that the prior distribution be known, empirical Bayes methods require only that it be in a certain family of distributions, indexed by hyperparameters that can be estimated from the available data. This structure is of interest per se, in addition to its value in allowing for improved estimation of individual parameters; for example, hypotheses regarding the existence of distinct subgroups in a collection of parameters can be considered under the empirical Bayes framework by allowing the hyperparameters to vary among subgroups. Though empirical Bayes methods have been applied in a variety of contexts, they have received little attention in the ecological literature. We describe the empirical Bayes approach in application to estimation of proportions, using data obtained in a community-wide study of cowbird parasitism rates for illustration. Since observed proportions based on small sample sizes are heavily adjusted toward the mean, extreme values among empirical Bayes estimates identify those species for which there is the greatest evidence of extreme parasitism rates. Applying a subgroup analysis to our data on cowbird parasitism rates, we conclude that parasitism rates for Neotropical Migrants as a group are no greater than those of Resident/Short-distance Migrant species in this forest community. Our data and analyses demonstrate that the parasitism rates for certain Neotropical Migrant species are remarkably low (Wood Thrush and Rose-breasted Grosbeak) while those for others are remarkably high (Ovenbird and Red-eyed Vireo).

  3. MC3: Multi-core Markov-chain Monte Carlo code

    NASA Astrophysics Data System (ADS)

    Cubillos, Patricio; Harrington, Joseph; Lust, Nate; Foster, AJ; Stemm, Madison; Loredo, Tom; Stevenson, Kevin; Campo, Chris; Hardin, Matt; Hardy, Ryan

    2016-10-01

    MC3 (Multi-core Markov-chain Monte Carlo) is a Bayesian statistics tool that can be executed from the shell prompt or interactively through the Python interpreter with single- or multiple-CPU parallel computing. It offers Markov-chain Monte Carlo (MCMC) posterior-distribution sampling for several algorithms, Levenberg-Marquardt least-squares optimization, and uniform non-informative, Jeffreys non-informative, or Gaussian-informative priors. MC3 can share the same value among multiple parameters and fix the value of parameters to constant values, and offers Gelman-Rubin convergence testing and correlated-noise estimation with time-averaging or wavelet-based likelihood estimation methods.

  4. Estimating Convection Parameters in the GFDL CM2.1 Model Using Ensemble Data Assimilation

    NASA Astrophysics Data System (ADS)

    Li, Shan; Zhang, Shaoqing; Liu, Zhengyu; Lu, Lv; Zhu, Jiang; Zhang, Xuefeng; Wu, Xinrong; Zhao, Ming; Vecchi, Gabriel A.; Zhang, Rong-Hua; Lin, Xiaopei

    2018-04-01

    Parametric uncertainty in convection parameterization is one major source of model errors that cause model climate drift. Convection parameter tuning has been widely studied in atmospheric models to help mitigate the problem. However, in a fully coupled general circulation model (CGCM), convection parameters which impact the ocean as well as the climate simulation may have different optimal values. This study explores the possibility of estimating convection parameters with an ensemble coupled data assimilation method in a CGCM. Impacts of the convection parameter estimation on climate analysis and forecast are analyzed. In a twin experiment framework, five convection parameters in the GFDL coupled model CM2.1 are estimated individually and simultaneously under both perfect and imperfect model regimes. Results show that the ensemble data assimilation method can help reduce the bias in convection parameters. With estimated convection parameters, the analyses and forecasts for both the atmosphere and the ocean are generally improved. It is also found that information in low latitudes is relatively more important for estimating convection parameters. This study further suggests that when important parameters in appropriate physical parameterizations are identified, incorporating their estimation into traditional ensemble data assimilation procedure could improve the final analysis and climate prediction.

  5. Off-line tracking of series parameters in distribution systems using AMI data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Williams, Tess L.; Sun, Yannan; Schneider, Kevin

    2016-05-01

    Electric distribution systems have historically lacked measurement points, and equipment is often operated to its failure point, resulting in customer outages. The widespread deployment of sensors at the distribution level is enabling observability. This paper presents an off-line parameter value tracking procedure that takes advantage of the increasing number of measurement devices being deployed at the distribution level to estimate changes in series impedance parameter values over time. The tracking of parameter values enables non-diurnal and non-seasonal change to be flagged for investigation. The presented method uses an unbalanced Distribution System State Estimation (DSSE) and a measurement residual-based parameter estimationmore » procedure. Measurement residuals from multiple measurement snapshots are combined in order to increase the effective local redundancy and improve the robustness of the calculations in the presence of measurement noise. Data from devices on the primary distribution system and from customer meters, via an AMI system, form the input data set. Results of simulations on the IEEE 13-Node Test Feeder are presented to illustrate the proposed approach applied to changes in series impedance parameters. A 5% change in series resistance elements can be detected in the presence of 2% measurement error when combining less than 1 day of measurement snapshots into a single estimate.« less

  6. Noise parameter estimation for poisson corrupted images using variance stabilization transforms.

    PubMed

    Jin, Xiaodan; Xu, Zhenyu; Hirakawa, Keigo

    2014-03-01

    Noise is present in all images captured by real-world image sensors. Poisson distribution is said to model the stochastic nature of the photon arrival process and agrees with the distribution of measured pixel values. We propose a method for estimating unknown noise parameters from Poisson corrupted images using properties of variance stabilization. With a significantly lower computational complexity and improved stability, the proposed estimation technique yields noise parameters that are comparable in accuracy to the state-of-art methods.

  7. A software tool to assess uncertainty in transient-storage model parameters using Monte Carlo simulations

    USGS Publications Warehouse

    Ward, Adam S.; Kelleher, Christa A.; Mason, Seth J. K.; Wagener, Thorsten; McIntyre, Neil; McGlynn, Brian L.; Runkel, Robert L.; Payn, Robert A.

    2017-01-01

    Researchers and practitioners alike often need to understand and characterize how water and solutes move through a stream in terms of the relative importance of in-stream and near-stream storage and transport processes. In-channel and subsurface storage processes are highly variable in space and time and difficult to measure. Storage estimates are commonly obtained using transient-storage models (TSMs) of the experimentally obtained solute-tracer test data. The TSM equations represent key transport and storage processes with a suite of numerical parameters. Parameter values are estimated via inverse modeling, in which parameter values are iteratively changed until model simulations closely match observed solute-tracer data. Several investigators have shown that TSM parameter estimates can be highly uncertain. When this is the case, parameter values cannot be used reliably to interpret stream-reach functioning. However, authors of most TSM studies do not evaluate or report parameter certainty. Here, we present a software tool linked to the One-dimensional Transport with Inflow and Storage (OTIS) model that enables researchers to conduct uncertainty analyses via Monte-Carlo parameter sampling and to visualize uncertainty and sensitivity results. We demonstrate application of our tool to 2 case studies and compare our results to output obtained from more traditional implementation of the OTIS model. We conclude by suggesting best practices for transient-storage modeling and recommend that future applications of TSMs include assessments of parameter certainty to support comparisons and more reliable interpretations of transport processes.

  8. Particle swarm optimization algorithm based parameters estimation and control of epileptiform spikes in a neural mass model

    NASA Astrophysics Data System (ADS)

    Shan, Bonan; Wang, Jiang; Deng, Bin; Wei, Xile; Yu, Haitao; Zhang, Zhen; Li, Huiyan

    2016-07-01

    This paper proposes an epilepsy detection and closed-loop control strategy based on Particle Swarm Optimization (PSO) algorithm. The proposed strategy can effectively suppress the epileptic spikes in neural mass models, where the epileptiform spikes are recognized as the biomarkers of transitions from the normal (interictal) activity to the seizure (ictal) activity. In addition, the PSO algorithm shows capabilities of accurate estimation for the time evolution of key model parameters and practical detection for all the epileptic spikes. The estimation effects of unmeasurable parameters are improved significantly compared with unscented Kalman filter. When the estimated excitatory-inhibitory ratio exceeds a threshold value, the epileptiform spikes can be inhibited immediately by adopting the proportion-integration controller. Besides, numerical simulations are carried out to illustrate the effectiveness of the proposed method as well as the potential value for the model-based early seizure detection and closed-loop control treatment design.

  9. Estimating the solute transport parameters of the spatial fractional advection-dispersion equation using Bees Algorithm

    NASA Astrophysics Data System (ADS)

    Mehdinejadiani, Behrouz

    2017-08-01

    This study represents the first attempt to estimate the solute transport parameters of the spatial fractional advection-dispersion equation using Bees Algorithm. The numerical studies as well as the experimental studies were performed to certify the integrity of Bees Algorithm. The experimental ones were conducted in a sandbox for homogeneous and heterogeneous soils. A detailed comparative study was carried out between the results obtained from Bees Algorithm and those from Genetic Algorithm and LSQNONLIN routines in FracFit toolbox. The results indicated that, in general, the Bees Algorithm much more accurately appraised the sFADE parameters in comparison with Genetic Algorithm and LSQNONLIN, especially in the heterogeneous soil and for α values near to 1 in the numerical study. Also, the results obtained from Bees Algorithm were more reliable than those from Genetic Algorithm. The Bees Algorithm showed the relative similar performances for all cases, while the Genetic Algorithm and the LSQNONLIN yielded different performances for various cases. The performance of LSQNONLIN strongly depends on the initial guess values so that, compared to the Genetic Algorithm, it can more accurately estimate the sFADE parameters by taking into consideration the suitable initial guess values. To sum up, the Bees Algorithm was found to be very simple, robust and accurate approach to estimate the transport parameters of the spatial fractional advection-dispersion equation.

  10. Estimating the solute transport parameters of the spatial fractional advection-dispersion equation using Bees Algorithm.

    PubMed

    Mehdinejadiani, Behrouz

    2017-08-01

    This study represents the first attempt to estimate the solute transport parameters of the spatial fractional advection-dispersion equation using Bees Algorithm. The numerical studies as well as the experimental studies were performed to certify the integrity of Bees Algorithm. The experimental ones were conducted in a sandbox for homogeneous and heterogeneous soils. A detailed comparative study was carried out between the results obtained from Bees Algorithm and those from Genetic Algorithm and LSQNONLIN routines in FracFit toolbox. The results indicated that, in general, the Bees Algorithm much more accurately appraised the sFADE parameters in comparison with Genetic Algorithm and LSQNONLIN, especially in the heterogeneous soil and for α values near to 1 in the numerical study. Also, the results obtained from Bees Algorithm were more reliable than those from Genetic Algorithm. The Bees Algorithm showed the relative similar performances for all cases, while the Genetic Algorithm and the LSQNONLIN yielded different performances for various cases. The performance of LSQNONLIN strongly depends on the initial guess values so that, compared to the Genetic Algorithm, it can more accurately estimate the sFADE parameters by taking into consideration the suitable initial guess values. To sum up, the Bees Algorithm was found to be very simple, robust and accurate approach to estimate the transport parameters of the spatial fractional advection-dispersion equation. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Estimating parametric phenotypes that determine anthesis date in Zea mays: Challenges in combining ecophysiological models with genetics

    PubMed Central

    Welch, Stephen M.; White, Jeffrey W.; Thorp, Kelly R.; Bello, Nora M.

    2018-01-01

    Ecophysiological crop models encode intra-species behaviors using parameters that are presumed to summarize genotypic properties of individual lines or cultivars. These genotype-specific parameters (GSP’s) can be interpreted as quantitative traits that can be mapped or otherwise analyzed, as are more conventional traits. The goal of this study was to investigate the estimation of parameters controlling maize anthesis date with the CERES-Maize model, based on 5,266 maize lines from 11 plantings at locations across the eastern United States. High performance computing was used to develop a database of 356 million simulated anthesis dates in response to four CERES-Maize model parameters. Although the resulting estimates showed high predictive value (R2 = 0.94), three issues presented serious challenges for use of GSP’s as traits. First (expressivity), the model was unable to express the observed data for 168 to 3,339 lines (depending on the combination of site-years), many of which ended up sharing the same parameter value irrespective of genetics. Second, for 2,254 lines, the model reproduced the data, but multiple parameter sets were equally effective (equifinality). Third, parameter values were highly dependent (p<10−6919) on the sets of environments used to estimate them (instability), calling in to question the assumption that they represent fundamental genetic traits. The issues of expressivity, equifinality and instability must be addressed before the genetic mapping of GSP’s becomes a robust means to help solve the genotype-to-phenotype problem in crops. PMID:29672629

  12. A new zonation algorithm with parameter estimation using hydraulic head and subsidence observations.

    PubMed

    Zhang, Meijing; Burbey, Thomas J; Nunes, Vitor Dos Santos; Borggaard, Jeff

    2014-01-01

    Parameter estimation codes such as UCODE_2005 are becoming well-known tools in groundwater modeling investigations. These programs estimate important parameter values such as transmissivity (T) and aquifer storage values (Sa ) from known observations of hydraulic head, flow, or other physical quantities. One drawback inherent in these codes is that the parameter zones must be specified by the user. However, such knowledge is often unknown even if a detailed hydrogeological description is available. To overcome this deficiency, we present a discrete adjoint algorithm for identifying suitable zonations from hydraulic head and subsidence measurements, which are highly sensitive to both elastic (Sske) and inelastic (Sskv) skeletal specific storage coefficients. With the advent of interferometric synthetic aperture radar (InSAR), distributed spatial and temporal subsidence measurements can be obtained. A synthetic conceptual model containing seven transmissivity zones, one aquifer storage zone and three interbed zones for elastic and inelastic storage coefficients were developed to simulate drawdown and subsidence in an aquifer interbedded with clay that exhibits delayed drainage. Simulated delayed land subsidence and groundwater head data are assumed to be the observed measurements, to which the discrete adjoint algorithm is called to create approximate spatial zonations of T, Sske , and Sskv . UCODE-2005 is then used to obtain the final optimal parameter values. Calibration results indicate that the estimated zonations calculated from the discrete adjoint algorithm closely approximate the true parameter zonations. This automation algorithm reduces the bias established by the initial distribution of zones and provides a robust parameter zonation distribution. © 2013, National Ground Water Association.

  13. The Impact of Multidirectional Item Parameter Drift on IRT Scaling Coefficients and Proficiency Estimates

    ERIC Educational Resources Information Center

    Han, Kyung T.; Wells, Craig S.; Sireci, Stephen G.

    2012-01-01

    Item parameter drift (IPD) occurs when item parameter values change from their original value over time. IPD may pose a serious threat to the fairness and validity of test score interpretations, especially when the goal of the assessment is to measure growth or improvement. In this study, we examined the effect of multidirectional IPD (i.e., some…

  14. VA-Index: Quantifying Assortativity Patterns in Networks with Multidimensional Nodal Attributes (Open Access)

    DTIC Science & Technology

    2016-01-27

    bias of the estimator U, bias(U), the difference between this estimator’s expected value and the true value of the parameter being estimated, i.e...biasðUÞ ¼ EðU yÞ ¼ EðUÞ y ð9Þ Based on the above definition, an unbiased estimator is one whose expected value is equal to the true value being...equal to 0.94 (p- value < 0.05), if we con- sider the pure ER network model as our baseline, and 0.31 (p- value < 0.05), if we control for the home

  15. Seasonal variability of the parameters of the Ball-Berry model of stomatal conductance in maize (Zea mays L.) and sunflower (Helianthus annuus L.) under well-watered and water-stressed conditions.

    PubMed

    Miner, Grace L; Bauerle, William L

    2017-09-01

    The Ball-Berry (BB) model of stomatal conductance (g s ) is frequently coupled with a model of assimilation to estimate water and carbon exchanges in plant canopies. The empirical slope (m) and 'residual' g s (g 0 ) parameters of the BB model influence transpiration estimates, but the time-intensive nature of measurement limits species-specific data on seasonal and stress responses. We measured m and g 0 seasonally and under different water availability for maize and sunflower. The statistical method used to estimate parameters impacted values nominally when inter-plant variability was low, but had substantial impact with larger inter-plant variability. Values for maize (m = 4.53 ± 0.65; g 0  = 0.017 ± 0.016 mol m -2 s -1 ) were 40% higher than other published values. In maize, we found no seasonal changes in m or g 0 , supporting the use of constant seasonal values, but water stress reduced both parameters. In sunflower, inter-plant variability of m and g 0 was large (m = 8.84 ± 3.77; g 0  = 0.354 ± 0.226 mol m -2 s -1 ), presenting a challenge to clear interpretation of seasonal and water stress responses - m values were stable seasonally, even as g 0 values trended downward, and m values trended downward with water stress while g 0 values declined substantially. © 2017 John Wiley & Sons Ltd.

  16. Systems identification using a modified Newton-Raphson method: A FORTRAN program

    NASA Technical Reports Server (NTRS)

    Taylor, L. W., Jr.; Iliff, K. W.

    1972-01-01

    A FORTRAN program is offered which computes a maximum likelihood estimate of the parameters of any linear, constant coefficient, state space model. For the case considered, the maximum likelihood estimate can be identical to that which minimizes simultaneously the weighted mean square difference between the computed and measured response of a system and the weighted square of the difference between the estimated and a priori parameter values. A modified Newton-Raphson or quasilinearization method is used to perform the minimization which typically requires several iterations. A starting technique is used which insures convergence for any initial values of the unknown parameters. The program and its operation are described in sufficient detail to enable the user to apply the program to his particular problem with a minimum of difficulty.

  17. The Model Human Processor and the Older Adult: Parameter Estimation and Validation within a Mobile Phone Task

    ERIC Educational Resources Information Center

    Jastrzembski, Tiffany S.; Charness, Neil

    2007-01-01

    The authors estimate weighted mean values for nine information processing parameters for older adults using the Card, Moran, and Newell (1983) Model Human Processor model. The authors validate a subset of these parameters by modeling two mobile phone tasks using two different phones and comparing model predictions to a sample of younger (N = 20;…

  18. Estimation of Physical Properties and Chemical Reactivity Parameters of Organic Compounds for Environmental Modeling by SPARC

    EPA Science Inventory

    Mathematical models for predicting the transport and fate of pollutants in the environment require reactivity parameter values that is value of the physical and chemical constants that govern reactivity. Although empirical structure activity relationships have been developed th...

  19. Restoration of acidic mine spoils with sewage sludge: II measurement of solids applied

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stucky, D.J.; Zoeller, A.L.

    1980-01-01

    Sewage sludge was incorporated in acidic strip mine spoils at rates equivalent to 0, 224, 336, and 448 dry metric tons (dmt)/ha and placed in pots in a greenhouse. Spoil parameters were determined 48 hours after sludge incorporation, Time Planting (P), and five months after orchardgrass (Dactylis glomerata L.) was planted, Time Harvest (H), in the pots. Parameters measured were: pH, organic matter content (OM), cation exchange capacity (CEC), electrical conductivity (EC) and yield. Values for each parameter were significantly different at the two sampling times. Correlation coefficient values were calculated for all parameters versus rates of applied sewage sludgemore » and all parameters versus each other. Multiple regressions were performed, stepwise, for all parameters versus rates of applied sewage sludge. Equations to predict amounts of sewage sludge incorporated in spoils were derived for individual and multiple parameters. Generally, measurements made at Time P achieved the highest correlation coefficient and multiple correlation coefficient values; therefore, the authors concluded data from Time P had the greatest predictability value. The most important value measured to predict rate of applied sewage sludge was pH and some additional accuracy was obtained by including CEC in equation. This experiment indicated that soil properties can be used to estimate amounts of sewage sludge solids required to reclaim acidic mine spoils and to estimate quantities incorporated.« less

  20. A Fortran 77 computer code for damped least-squares inversion of Slingram electromagnetic anomalies over thin tabular conductors

    NASA Astrophysics Data System (ADS)

    Dondurur, Derman; Sarı, Coşkun

    2004-07-01

    A FORTRAN 77 computer code is presented that permits the inversion of Slingram electromagnetic anomalies to an optimal conductor model. Damped least-squares inversion algorithm is used to estimate the anomalous body parameters, e.g. depth, dip and surface projection point of the target. Iteration progress is controlled by maximum relative error value and iteration continued until a tolerance value was satisfied, while the modification of Marquardt's parameter is controlled by sum of the squared errors value. In order to form the Jacobian matrix, the partial derivatives of theoretical anomaly expression with respect to the parameters being optimised are calculated by numerical differentiation by using first-order forward finite differences. A theoretical and two field anomalies are inserted to test the accuracy and applicability of the present inversion program. Inversion of the field data indicated that depth and the surface projection point parameters of the conductor are estimated correctly, however, considerable discrepancies appeared on the estimated dip angles. It is therefore concluded that the most important factor resulting in the misfit between observed and calculated data is due to the fact that the theory used for computing Slingram anomalies is valid for only thin conductors and this assumption might have caused incorrect dip estimates in the case of wide conductors.

  1. Thermodynamic modeling of transcription: sensitivity analysis differentiates biological mechanism from mathematical model-induced effects.

    PubMed

    Dresch, Jacqueline M; Liu, Xiaozhou; Arnosti, David N; Ay, Ahmet

    2010-10-24

    Quantitative models of gene expression generate parameter values that can shed light on biological features such as transcription factor activity, cooperativity, and local effects of repressors. An important element in such investigations is sensitivity analysis, which determines how strongly a model's output reacts to variations in parameter values. Parameters of low sensitivity may not be accurately estimated, leading to unwarranted conclusions. Low sensitivity may reflect the nature of the biological data, or it may be a result of the model structure. Here, we focus on the analysis of thermodynamic models, which have been used extensively to analyze gene transcription. Extracted parameter values have been interpreted biologically, but until now little attention has been given to parameter sensitivity in this context. We apply local and global sensitivity analyses to two recent transcriptional models to determine the sensitivity of individual parameters. We show that in one case, values for repressor efficiencies are very sensitive, while values for protein cooperativities are not, and provide insights on why these differential sensitivities stem from both biological effects and the structure of the applied models. In a second case, we demonstrate that parameters that were thought to prove the system's dependence on activator-activator cooperativity are relatively insensitive. We show that there are numerous parameter sets that do not satisfy the relationships proferred as the optimal solutions, indicating that structural differences between the two types of transcriptional enhancers analyzed may not be as simple as altered activator cooperativity. Our results emphasize the need for sensitivity analysis to examine model construction and forms of biological data used for modeling transcriptional processes, in order to determine the significance of estimated parameter values for thermodynamic models. Knowledge of parameter sensitivities can provide the necessary context to determine how modeling results should be interpreted in biological systems.

  2. An improved method to estimate reflectance parameters for high dynamic range imaging

    NASA Astrophysics Data System (ADS)

    Li, Shiying; Deguchi, Koichiro; Li, Renfa; Manabe, Yoshitsugu; Chihara, Kunihiro

    2008-01-01

    Two methods are described to accurately estimate diffuse and specular reflectance parameters for colors, gloss intensity and surface roughness, over the dynamic range of the camera used to capture input images. Neither method needs to segment color areas on an image, or to reconstruct a high dynamic range (HDR) image. The second method improves on the first, bypassing the requirement for specific separation of diffuse and specular reflection components. For the latter method, diffuse and specular reflectance parameters are estimated separately, using the least squares method. Reflection values are initially assumed to be diffuse-only reflection components, and are subjected to the least squares method to estimate diffuse reflectance parameters. Specular reflection components, obtained by subtracting the computed diffuse reflection components from reflection values, are then subjected to a logarithmically transformed equation of the Torrance-Sparrow reflection model, and specular reflectance parameters for gloss intensity and surface roughness are finally estimated using the least squares method. Experiments were carried out using both methods, with simulation data at different saturation levels, generated according to the Lambert and Torrance-Sparrow reflection models, and the second method, with spectral images captured by an imaging spectrograph and a moving light source. Our results show that the second method can estimate the diffuse and specular reflectance parameters for colors, gloss intensity and surface roughness more accurately and faster than the first one, so that colors and gloss can be reproduced more efficiently for HDR imaging.

  3. Future possible crop yield scenarios under multiple SSP and RCP scenarios.

    NASA Astrophysics Data System (ADS)

    Sakurai, G.; Yokozawa, M.; Nishimori, M.; Okada, M.

    2016-12-01

    Understanding the effect of future climate change on global crop yields is one of the most important tasks for global food security. Future crop yields would be influenced by climatic factors such as the changes of temperature, precipitation and atmospheric carbon dioxide concentration. On the other hand, the effect of the changes of agricultural technologies such as crop varieties, pesticide and fertilizer input on crop yields have large uncertainty. However, not much is available on the contribution ratio of each factor under the future climate change scenario. We estimated the future global yields of four major crops (maize, soybean, rice and wheat) under three Shared Socio Economic Pathways (SSPs) and four Representative Concentration Pathways (RCPs). For this purpose, firstly, we estimated a parameter of a process based model (PRYSBI2) using a Bayesian method for each 1.125 degree spatial grid. The model parameter is relevant to the agricultural technology (we call "technological parameter" here after). Then, we analyzed the relationship between the values of technological parameter and GDP values. We found that the estimated values of the technological parameter were positively correlated with the GDP. Using the estimated relationship, we predicted future crop yield during 2020 and 2100 under SSP1, SSP2 and SSP3 scenarios and RCP 2.6, 4.5, 6.0 and 8.5. The estimated crop yields were different among SSP scenarios. However, we found that the yield difference attributable to SSPs were smaller than those attributable to CO2 fertilization effects and climate change. Particularly, the estimated effect of the change of atmospheric carbon dioxide concentration on global yields was more than four times larger than that of GDP for C3 crops.

  4. Space Shuttle propulsion parameter estimation using optimal estimation techniques, volume 1

    NASA Technical Reports Server (NTRS)

    1983-01-01

    The mathematical developments and their computer program implementation for the Space Shuttle propulsion parameter estimation project are summarized. The estimation approach chosen is the extended Kalman filtering with a modified Bryson-Frazier smoother. Its use here is motivated by the objective of obtaining better estimates than those available from filtering and to eliminate the lag associated with filtering. The estimation technique uses as the dynamical process the six degree equations-of-motion resulting in twelve state vector elements. In addition to these are mass and solid propellant burn depth as the ""system'' state elements. The ""parameter'' state elements can include aerodynamic coefficient, inertia, center-of-gravity, atmospheric wind, etc. deviations from referenced values. Propulsion parameter state elements have been included not as options just discussed but as the main parameter states to be estimated. The mathematical developments were completed for all these parameters. Since the systems dynamics and measurement processes are non-linear functions of the states, the mathematical developments are taken up almost entirely by the linearization of these equations as required by the estimation algorithms.

  5. Computation of Standard Errors

    PubMed Central

    Dowd, Bryan E; Greene, William H; Norton, Edward C

    2014-01-01

    Objectives We discuss the problem of computing the standard errors of functions involving estimated parameters and provide the relevant computer code for three different computational approaches using two popular computer packages. Study Design We show how to compute the standard errors of several functions of interest: the predicted value of the dependent variable for a particular subject, and the effect of a change in an explanatory variable on the predicted value of the dependent variable for an individual subject and average effect for a sample of subjects. Empirical Application Using a publicly available dataset, we explain three different methods of computing standard errors: the delta method, Krinsky–Robb, and bootstrapping. We provide computer code for Stata 12 and LIMDEP 10/NLOGIT 5. Conclusions In most applications, choice of the computational method for standard errors of functions of estimated parameters is a matter of convenience. However, when computing standard errors of the sample average of functions that involve both estimated parameters and nonstochastic explanatory variables, it is important to consider the sources of variation in the function's values. PMID:24800304

  6. Characterization of Initial Parameter Information for Lifetime Prediction of Electronic Devices.

    PubMed

    Li, Zhigang; Liu, Boying; Yuan, Mengxiong; Zhang, Feifei; Guo, Jiaqiang

    2016-01-01

    Newly manufactured electronic devices are subject to different levels of potential defects existing among the initial parameter information of the devices. In this study, a characterization of electromagnetic relays that were operated at their optimal performance with appropriate and steady parameter values was performed to estimate the levels of their potential defects and to develop a lifetime prediction model. First, the initial parameter information value and stability were quantified to measure the performance of the electronics. In particular, the values of the initial parameter information were estimated using the probability-weighted average method, whereas the stability of the parameter information was determined by using the difference between the extrema and end points of the fitting curves for the initial parameter information. Second, a lifetime prediction model for small-sized samples was proposed on the basis of both measures. Finally, a model for the relationship of the initial contact resistance and stability over the lifetime of the sampled electromagnetic relays was proposed and verified. A comparison of the actual and predicted lifetimes of the relays revealed a 15.4% relative error, indicating that the lifetime of electronic devices can be predicted based on their initial parameter information.

  7. Characterization of Initial Parameter Information for Lifetime Prediction of Electronic Devices

    PubMed Central

    Li, Zhigang; Liu, Boying; Yuan, Mengxiong; Zhang, Feifei; Guo, Jiaqiang

    2016-01-01

    Newly manufactured electronic devices are subject to different levels of potential defects existing among the initial parameter information of the devices. In this study, a characterization of electromagnetic relays that were operated at their optimal performance with appropriate and steady parameter values was performed to estimate the levels of their potential defects and to develop a lifetime prediction model. First, the initial parameter information value and stability were quantified to measure the performance of the electronics. In particular, the values of the initial parameter information were estimated using the probability-weighted average method, whereas the stability of the parameter information was determined by using the difference between the extrema and end points of the fitting curves for the initial parameter information. Second, a lifetime prediction model for small-sized samples was proposed on the basis of both measures. Finally, a model for the relationship of the initial contact resistance and stability over the lifetime of the sampled electromagnetic relays was proposed and verified. A comparison of the actual and predicted lifetimes of the relays revealed a 15.4% relative error, indicating that the lifetime of electronic devices can be predicted based on their initial parameter information. PMID:27907188

  8. Information fusion methods based on physical laws.

    PubMed

    Rao, Nageswara S V; Reister, David B; Barhen, Jacob

    2005-01-01

    We consider systems whose parameters satisfy certain easily computable physical laws. Each parameter is directly measured by a number of sensors, or estimated using measurements, or both. The measurement process may introduce both systematic and random errors which may then propagate into the estimates. Furthermore, the actual parameter values are not known since every parameter is measured or estimated, which makes the existing sample-based fusion methods inapplicable. We propose a fusion method for combining the measurements and estimators based on the least violation of physical laws that relate the parameters. Under fairly general smoothness and nonsmoothness conditions on the physical laws, we show the asymptotic convergence of our method and also derive distribution-free performance bounds based on finite samples. For suitable choices of the fuser classes, we show that for each parameter the fused estimate is probabilistically at least as good as its best measurement as well as best estimate. We illustrate the effectiveness of this method for a practical problem of fusing well-log data in methane hydrate exploration.

  9. Estimation of Pulse Transit Time as a Function of Blood Pressure Using a Nonlinear Arterial Tube-Load Model.

    PubMed

    Gao, Mingwu; Cheng, Hao-Min; Sung, Shih-Hsien; Chen, Chen-Huan; Olivier, Nicholas Bari; Mukkamala, Ramakrishna

    2017-07-01

    pulse transit time (PTT) varies with blood pressure (BP) throughout the cardiac cycle, yet, because of wave reflection, only one PTT value at the diastolic BP level is conventionally estimated from proximal and distal BP waveforms. The objective was to establish a technique to estimate multiple PTT values at different BP levels in the cardiac cycle. a technique was developed for estimating PTT as a function of BP (to indicate the PTT value for every BP level) from proximal and distal BP waveforms. First, a mathematical transformation from one waveform to the other is defined in terms of the parameters of a nonlinear arterial tube-load model accounting for BP-dependent arterial compliance and wave reflection. Then, the parameters are estimated by optimally fitting the waveforms to each other via the model-based transformation. Finally, PTT as a function of BP is specified by the parameters. The technique was assessed in animals and patients in several ways including the ability of its estimated PTT-BP function to serve as a subject-specific curve for calibrating PTT to BP. the calibration curve derived by the technique during a baseline period yielded bias and precision errors in mean BP of 5.1 ± 0.9 and 6.6 ± 1.0 mmHg, respectively, during hemodynamic interventions that varied mean BP widely. the new technique may permit, for the first time, estimation of PTT values throughout the cardiac cycle from proximal and distal waveforms. the technique could potentially be applied to improve arterial stiffness monitoring and help realize cuff-less BP monitoring.

  10. Estimated value of insurance premium due to Citarum River flood by using Bayesian method

    NASA Astrophysics Data System (ADS)

    Sukono; Aisah, I.; Tampubolon, Y. R. H.; Napitupulu, H.; Supian, S.; Subiyanto; Sidi, P.

    2018-03-01

    Citarum river flood in South Bandung, West Java Indonesia, often happens every year. It causes property damage, producing economic loss. The risk of loss can be mitigated by following the flood insurance program. In this paper, we discussed about the estimated value of insurance premiums due to Citarum river flood by Bayesian method. It is assumed that the risk data for flood losses follows the Pareto distribution with the right fat-tail. The estimation of distribution model parameters is done by using Bayesian method. First, parameter estimation is done with assumption that prior comes from Gamma distribution family, while observation data follow Pareto distribution. Second, flood loss data is simulated based on the probability of damage in each flood affected area. The result of the analysis shows that the estimated premium value of insurance based on pure premium principle is as follows: for the loss value of IDR 629.65 million of premium IDR 338.63 million; for a loss of IDR 584.30 million of its premium IDR 314.24 million; and the loss value of IDR 574.53 million of its premium IDR 308.95 million. The premium value estimator can be used as neither a reference in the decision of reasonable premium determination, so as not to incriminate the insured, nor it result in loss of the insurer.

  11. Estimation of Saxophone Control Parameters by Convex Optimization.

    PubMed

    Wang, Cheng-I; Smyth, Tamara; Lipton, Zachary C

    2014-12-01

    In this work, an approach to jointly estimating the tone hole configuration (fingering) and reed model parameters of a saxophone is presented. The problem isn't one of merely estimating pitch as one applied fingering can be used to produce several different pitches by bugling or overblowing. Nor can a fingering be estimated solely by the spectral envelope of the produced sound (as it might for estimation of vocal tract shape in speech) since one fingering can produce markedly different spectral envelopes depending on the player's embouchure and control of the reed. The problem is therefore addressed by jointly estimating both the reed (source) parameters and the fingering (filter) of a saxophone model using convex optimization and 1) a bank of filter frequency responses derived from measurement of the saxophone configured with all possible fingerings and 2) sample recordings of notes produced using all possible fingerings, played with different overblowing, dynamics and timbre. The saxophone model couples one of several possible frequency response pairs (corresponding to the applied fingering), and a quasi-static reed model generating input pressure at the mouthpiece, with control parameters being blowing pressure and reed stiffness. Applied fingering and reed parameters are estimated for a given recording by formalizing a minimization problem, where the cost function is the error between the recording and the synthesized sound produced by the model having incremental parameter values for blowing pressure and reed stiffness. The minimization problem is nonlinear and not differentiable and is made solvable using convex optimization. The performance of the fingering identification is evaluated with better accuracy than previous reported value.

  12. Mixing effects on apparent reaction rates and isotope fractionation during denitrification in a heterogeneous aquifer

    USGS Publications Warehouse

    Green, Christopher T.; Böhlke, John Karl; Bekins, Barbara A.; Phillips, Steven P.

    2010-01-01

    Gradients in contaminant concentrations and isotopic compositions commonly are used to derive reaction parameters for natural attenuation in aquifers. Differences between field‐scale (apparent) estimated reaction rates and isotopic fractionations and local‐scale (intrinsic) effects are poorly understood for complex natural systems. For a heterogeneous alluvial fan aquifer, numerical models and field observations were used to study the effects of physical heterogeneity on reaction parameter estimates. Field measurements included major ions, age tracers, stable isotopes, and dissolved gases. Parameters were estimated for the O2 reduction rate, denitrification rate, O2 threshold for denitrification, and stable N isotope fractionation during denitrification. For multiple geostatistical realizations of the aquifer, inverse modeling was used to establish reactive transport simulations that were consistent with field observations and served as a basis for numerical experiments to compare sample‐based estimates of “apparent” parameters with “true“ (intrinsic) values. For this aquifer, non‐Gaussian dispersion reduced the magnitudes of apparent reaction rates and isotope fractionations to a greater extent than Gaussian mixing alone. Apparent and true rate constants and fractionation parameters can differ by an order of magnitude or more, especially for samples subject to slow transport, long travel times, or rapid reactions. The effect of mixing on apparent N isotope fractionation potentially explains differences between previous laboratory and field estimates. Similarly, predicted effects on apparent O2threshold values for denitrification are consistent with previous reports of higher values in aquifers than in the laboratory. These results show that hydrogeological complexity substantially influences the interpretation and prediction of reactive transport.

  13. Estimation of parameter uncertainty for an activated sludge model using Bayesian inference: a comparison with the frequentist method.

    PubMed

    Zonta, Zivko J; Flotats, Xavier; Magrí, Albert

    2014-08-01

    The procedure commonly used for the assessment of the parameters included in activated sludge models (ASMs) relies on the estimation of their optimal value within a confidence region (i.e. frequentist inference). Once optimal values are estimated, parameter uncertainty is computed through the covariance matrix. However, alternative approaches based on the consideration of the model parameters as probability distributions (i.e. Bayesian inference), may be of interest. The aim of this work is to apply (and compare) both Bayesian and frequentist inference methods when assessing uncertainty for an ASM-type model, which considers intracellular storage and biomass growth, simultaneously. Practical identifiability was addressed exclusively considering respirometric profiles based on the oxygen uptake rate and with the aid of probabilistic global sensitivity analysis. Parameter uncertainty was thus estimated according to both the Bayesian and frequentist inferential procedures. Results were compared in order to evidence the strengths and weaknesses of both approaches. Since it was demonstrated that Bayesian inference could be reduced to a frequentist approach under particular hypotheses, the former can be considered as a more generalist methodology. Hence, the use of Bayesian inference is encouraged for tackling inferential issues in ASM environments.

  14. Nonlinear, discrete flood event models, 1. Bayesian estimation of parameters

    NASA Astrophysics Data System (ADS)

    Bates, Bryson C.; Townley, Lloyd R.

    1988-05-01

    In this paper (Part 1), a Bayesian procedure for parameter estimation is applied to discrete flood event models. The essence of the procedure is the minimisation of a sum of squares function for models in which the computed peak discharge is nonlinear in terms of the parameters. This objective function is dependent on the observed and computed peak discharges for several storms on the catchment, information on the structure of observation error, and prior information on parameter values. The posterior covariance matrix gives a measure of the precision of the estimated parameters. The procedure is demonstrated using rainfall and runoff data from seven Australian catchments. It is concluded that the procedure is a powerful alternative to conventional parameter estimation techniques in situations where a number of floods are available for parameter estimation. Parts 2 and 3 will discuss the application of statistical nonlinearity measures and prediction uncertainty analysis to calibrated flood models. Bates (this volume) and Bates and Townley (this volume).

  15. Quantitative body DW-MRI biomarkers uncertainty estimation using unscented wild-bootstrap.

    PubMed

    Freiman, M; Voss, S D; Mulkern, R V; Perez-Rossello, J M; Warfield, S K

    2011-01-01

    We present a new method for the uncertainty estimation of diffusion parameters for quantitative body DW-MRI assessment. Diffusion parameters uncertainty estimation from DW-MRI is necessary for clinical applications that use these parameters to assess pathology. However, uncertainty estimation using traditional techniques requires repeated acquisitions, which is undesirable in routine clinical use. Model-based bootstrap techniques, for example, assume an underlying linear model for residuals rescaling and cannot be utilized directly for body diffusion parameters uncertainty estimation due to the non-linearity of the body diffusion model. To offset this limitation, our method uses the Unscented transform to compute the residuals rescaling parameters from the non-linear body diffusion model, and then applies the wild-bootstrap method to infer the body diffusion parameters uncertainty. Validation through phantom and human subject experiments shows that our method identify the regions with higher uncertainty in body DWI-MRI model parameters correctly with realtive error of -36% in the uncertainty values.

  16. Identification of dominant interactions between climatic seasonality, catchment characteristics and agricultural activities on Budyko-type equation parameter estimation

    NASA Astrophysics Data System (ADS)

    Xing, Wanqiu; Wang, Weiguang; Shao, Quanxi; Yong, Bin

    2018-01-01

    Quantifying precipitation (P) partition into evapotranspiration (E) and runoff (Q) is of great importance for global and regional water availability assessment. Budyko framework serves as a powerful tool to make simple and transparent estimation for the partition, using a single parameter, to characterize the shape of the Budyko curve for a "specific basin", where the single parameter reflects the overall effect by not only climatic seasonality, catchment characteristics (e.g., soil, topography and vegetation) but also agricultural activities (e.g., cultivation and irrigation). At the regional scale, these influencing factors are interconnected, and the interactions between them can also affect the single parameter of Budyko-type equations' estimating. Here we employ the multivariate adaptive regression splines (MARS) model to estimate the Budyko curve shape parameter (n in the Choudhury's equation, one form of the Budyko framework) of the selected 96 catchments across China using a data set of long-term averages for climatic seasonality, catchment characteristics and agricultural activities. Results show average storm depth (ASD), vegetation coverage (M), and seasonality index of precipitation (SI) are three statistically significant factors affecting the Budyko parameter. More importantly, four pairs of interactions are recognized by the MARS model as: The interaction between CA (percentage of cultivated land area to total catchment area) and ASD shows that the cultivation can weaken the reducing effect of high ASD (>46.78 mm) on the Budyko parameter estimating. Drought (represented by the value of Palmer drought severity index < -0.74) and uneven distribution of annual rainfall (represented by the value of coefficient of variation of precipitation > 0.23) tend to enhance the Budyko parameter reduction by large SI (>0.797). Low vegetation coverage (34.56%) is likely to intensify the rising effect on evapotranspiration ratio by IA (percentage of irrigation area to total catchment area). The Budyko n values estimated by the MARS model reproduce the calculated ones by the observation well for the selected 96 catchments (with R = 0.817, MAE = 4.09). Compared to the multiple stepwise regression model estimating the parameter n taken the influencing factors as independent inputs, the MARS model enhances the capability of the Budyko framework for assessing water availability at regional scale using readily available data.

  17. Estimation and applicability of attenuation characteristics for source parameters and scaling relations in the Garhwal Kumaun Himalaya region, India

    NASA Astrophysics Data System (ADS)

    Singh, Rakesh; Paul, Ajay; Kumar, Arjun; Kumar, Parveen; Sundriyal, Y. P.

    2018-06-01

    Source parameters of the small to moderate earthquakes are significant for understanding the dynamic rupture process, the scaling relations of the earthquakes and for assessment of seismic hazard potential of a region. In this study, the source parameters were determined for 58 small to moderate size earthquakes (3.0 ≤ Mw ≤ 5.0) occurred during 2007-2015 in the Garhwal-Kumaun region. The estimated shear wave quality factor (Qβ(f)) values for each station at different frequencies have been applied to eliminate any bias in the determination of source parameters. The Qβ(f) values have been estimated by using coda wave normalization method in the frequency range 1.5-16 Hz. A frequency-dependent S wave quality factor relation is obtained as Qβ(f) = (152.9 ± 7) f(0.82±0.005) by fitting a power-law frequency dependence model for the estimated values over the whole study region. The spectral (low-frequency spectral level and corner frequency) and source (static stress drop, seismic moment, apparent stress and radiated energy) parameters are obtained assuming ω-2 source model. The displacement spectra are corrected for estimated frequency-dependent attenuation, site effect using spectral decay parameter "Kappa". The frequency resolution limit was resolved by quantifying the bias in corner frequencies, stress drop and radiated energy estimates due to finite-bandwidth effect. The data of the region shows shallow focused earthquakes with low stress drop. The estimation of Zúñiga parameter (ε) suggests the partial stress drop mechanism in the region. The observed low stress drop and apparent stress can be explained by partial stress drop and low effective stress model. Presence of subsurface fluid at seismogenic depth certainly manipulates the dynamics of the region. However, the limited event selection may strongly bias the scaling relation even after taking as much as possible precaution in considering effects of finite bandwidth, attenuation and site corrections. Although, the scaling can be improved further with the integration of large dataset of microearthquakes and use of a stable and robust approach.

  18. Estimation of distributional parameters for censored trace level water quality data: 2. Verification and applications

    USGS Publications Warehouse

    Helsel, Dennis R.; Gilliom, Robert J.

    1986-01-01

    Estimates of distributional parameters (mean, standard deviation, median, interquartile range) are often desired for data sets containing censored observations. Eight methods for estimating these parameters have been evaluated by R. J. Gilliom and D. R. Helsel (this issue) using Monte Carlo simulations. To verify those findings, the same methods are now applied to actual water quality data. The best method (lowest root-mean-squared error (rmse)) over all parameters, sample sizes, and censoring levels is log probability regression (LR), the method found best in the Monte Carlo simulations. Best methods for estimating moment or percentile parameters separately are also identical to the simulations. Reliability of these estimates can be expressed as confidence intervals using rmse and bias values taken from the simulation results. Finally, a new simulation study shows that best methods for estimating uncensored sample statistics from censored data sets are identical to those for estimating population parameters. Thus this study and the companion study by Gilliom and Helsel form the basis for making the best possible estimates of either population parameters or sample statistics from censored water quality data, and for assessments of their reliability.

  19. 40 CFR 98.85 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... missing data. A complete record of all measured parameters used in the GHG emissions calculations in § 98... substitute data value for the missing parameter shall be used in the calculations. The owner or operator must...

  20. 40 CFR 98.85 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... missing data. A complete record of all measured parameters used in the GHG emissions calculations in § 98... substitute data value for the missing parameter shall be used in the calculations. The owner or operator must...

  1. 40 CFR 98.85 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... missing data. A complete record of all measured parameters used in the GHG emissions calculations in § 98... substitute data value for the missing parameter shall be used in the calculations. The owner or operator must...

  2. 40 CFR 98.185 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... missing data. A complete record of all measured parameters used in the GHG emissions calculations in § 98... substitute data value for the missing parameter shall be used in the calculations as specified in the...

  3. 40 CFR 98.85 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... missing data. A complete record of all measured parameters used in the GHG emissions calculations in § 98... substitute data value for the missing parameter shall be used in the calculations. The owner or operator must...

  4. 40 CFR 98.185 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... missing data. A complete record of all measured parameters used in the GHG emissions calculations in § 98... substitute data value for the missing parameter shall be used in the calculations as specified in the...

  5. 40 CFR 98.185 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... missing data. A complete record of all measured parameters used in the GHG emissions calculations in § 98... substitute data value for the missing parameter shall be used in the calculations as specified in the...

  6. 40 CFR 98.185 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... missing data. A complete record of all measured parameters used in the GHG emissions calculations in § 98... substitute data value for the missing parameter shall be used in the calculations as specified in the...

  7. Optimizing the bio-optical algorithm for estimating chlorophyll-a and phycocyanin concentrations in inland waters in Korea

    USDA-ARS?s Scientific Manuscript database

    Several bio-optical algorithms were developed to estimate the chlorophyll-a (Chl-a) and phycocyanin (PC) concentrations in inland waters. This study aimed at identifying the influence of the algorithm parameters and wavelength bands on output variables and searching optimal parameter values. The opt...

  8. Inverse modeling with RZWQM2 to predict water quality

    USGS Publications Warehouse

    Nolan, Bernard T.; Malone, Robert W.; Ma, Liwang; Green, Christopher T.; Fienen, Michael N.; Jaynes, Dan B.

    2011-01-01

    This chapter presents guidelines for autocalibration of the Root Zone Water Quality Model (RZWQM2) by inverse modeling using PEST parameter estimation software (Doherty, 2010). Two sites with diverse climate and management were considered for simulation of N losses by leaching and in drain flow: an almond [Prunus dulcis (Mill.) D.A. Webb] orchard in the San Joaquin Valley, California and the Walnut Creek watershed in central Iowa, which is predominantly in corn (Zea mays L.)–soybean [Glycine max (L.) Merr.] rotation. Inverse modeling provides an objective statistical basis for calibration that involves simultaneous adjustment of model parameters and yields parameter confidence intervals and sensitivities. We describe operation of PEST in both parameter estimation and predictive analysis modes. The goal of parameter estimation is to identify a unique set of parameters that minimize a weighted least squares objective function, and the goal of predictive analysis is to construct a nonlinear confidence interval for a prediction of interest by finding a set of parameters that maximizes or minimizes the prediction while maintaining the model in a calibrated state. We also describe PEST utilities (PAR2PAR, TSPROC) for maintaining ordered relations among model parameters (e.g., soil root growth factor) and for post-processing of RZWQM2 outputs representing different cropping practices at the Iowa site. Inverse modeling provided reasonable fits to observed water and N fluxes and directly benefitted the modeling through: (i) simultaneous adjustment of multiple parameters versus one-at-a-time adjustment in manual approaches; (ii) clear indication by convergence criteria of when calibration is complete; (iii) straightforward detection of nonunique and insensitive parameters, which can affect the stability of PEST and RZWQM2; and (iv) generation of confidence intervals for uncertainty analysis of parameters and model predictions. Composite scaled sensitivities, which reflect the total information provided by the observations for a parameter, indicated that most of the RZWQM2 parameters at the California study site (CA) and Iowa study site (IA) could be reliably estimated by regression. Correlations obtained in the CA case indicated that all model parameters could be uniquely estimated by inverse modeling. Although water content at field capacity was highly correlated with bulk density (−0.94), the correlation is less than the threshold for nonuniqueness (0.95, absolute value basis). Additionally, we used truncated singular value decomposition (SVD) at CA to mitigate potential problems with highly correlated and insensitive parameters. Singular value decomposition estimates linear combinations (eigenvectors) of the original process-model parameters. Parameter confidence intervals (CIs) at CA indicated that parameters were reliably estimated with the possible exception of an organic pool transfer coefficient (R45), which had a comparatively wide CI. However, the 95% confidence interval for R45 (0.03–0.35) is mostly within the range of values reported for this parameter. Predictive analysis at CA generated confidence intervals that were compared with independently measured annual water flux (groundwater recharge) and median nitrate concentration in a collocated monitoring well as part of model evaluation. Both the observed recharge (42.3 cm yr−1) and nitrate concentration (24.3 mg L−1) were within their respective 90% confidence intervals, indicating that overall model error was within acceptable limits.

  9. a Comparison Between Two Ols-Based Approaches to Estimating Urban Multifractal Parameters

    NASA Astrophysics Data System (ADS)

    Huang, Lin-Shan; Chen, Yan-Guang

    Multifractal theory provides a new spatial analytical tool for urban studies, but many basic problems remain to be solved. Among various pending issues, the most significant one is how to obtain proper multifractal dimension spectrums. If an algorithm is improperly used, the parameter spectrums will be abnormal. This paper is devoted to investigating two ordinary least squares (OLS)-based approaches for estimating urban multifractal parameters. Using empirical study and comparative analysis, we demonstrate how to utilize the adequate linear regression to calculate multifractal parameters. The OLS regression analysis has two different approaches. One is that the intercept is fixed to zero, and the other is that the intercept is not limited. The results of comparative study show that the zero-intercept regression yields proper multifractal parameter spectrums within certain scale range of moment order, while the common regression method often leads to abnormal multifractal parameter values. A conclusion can be reached that fixing the intercept to zero is a more advisable regression method for multifractal parameters estimation, and the shapes of spectral curves and value ranges of fractal parameters can be employed to diagnose urban problems. This research is helpful for scientists to understand multifractal models and apply a more reasonable technique to multifractal parameter calculations.

  10. Delineation and Analysis of Uncertainty of Contributing Areas to Wells at the Southbury Training School, Southbury, Connecticut

    USGS Publications Warehouse

    Starn, J. Jeffrey; Stone, Janet Radway; Mullaney, John R.

    2000-01-01

    Contributing areas to public-supply wells at the Southbury Training School in Southbury, Connecticut, were mapped by simulating ground-water flow in stratified glacial deposits in the lower Transylvania Brook watershed. The simulation used nonlinear regression methods and informational statistics to estimate parameters of a ground-water flow model using drawdown data from an aquifer test. The goodness of fit of the model and the uncertainty associated with model predictions were statistically measured. A watershed-scale model, depicting large-scale ground-water flow in the Transylvania Brook watershed, was used to estimate the distribution of groundwater recharge. Estimates of recharge from 10 small basins in the watershed differed on the basis of the drainage characteristics of each basin. Small basins having well-defined stream channels contributed less ground-water recharge than basins having no defined channels because potential ground-water recharge was carried away in the stream channel. Estimates of ground-water recharge were used in an aquifer-scale parameter-estimation model. Seven variations of the ground-water-flow system were posed, each representing the ground-water-flow system in slightly different but realistic ways. The model that most closely reproduced measured hydraulic heads and flows with realistic parameter values was selected as the most representative of the ground-water-flow system and was used to delineate boundaries of the contributing areas. The model fit revealed no systematic model error, which indicates that the model is likely to represent the major characteristics of the actual system. Parameter values estimated during the simulation are as follows: horizontal hydraulic conductivity of coarse-grained deposits, 154 feet per day; vertical hydraulic conductivity of coarse-grained deposits, 0.83 feet per day; horizontal hydraulic conductivity of fine-grained deposits, 29 feet per day; specific yield, 0.007; specific storage, 1.6E-05. Average annual recharge was estimated using the watershed-scale model with no parameter estimation and was determined to be 24 inches per year in the valley areas and 9 inches per year in the upland areas. The parameter estimates produced in the model are similar to expected values, with two exceptions. The estimated specific yield of the stratified glacial deposits is lower than expected, which could be caused by the layered nature of the deposits. The recharge estimate produced by the model was also lower?about 32 percent of the average annual rate. This could be caused by the timing of the aquifer test with respect to the annual cycle of ground-water recharge, and by some of the expected recharge going to parts of the flow system that were not simulated. The data used in the calibration were collected during an aquifer test from October 30 to November 4, 1996. The model fit was very good, as indicated by the correlation coefficient (0.999) between the weighted simulated values and weighted observed values. The model also reproduced the general rise in ground-water levels caused by ground-water recharge and the cyclic fluctuations caused by pumping prior to the aquifer test. Contributing areas were delineated using a particle-tracking procedure. Hypothetical particles of water were introduced at each model cell in the top layer and were tracked to determine whether or not they reached the pumped well. A deterministic contributing area was calculated using the calibrated model, and a probabilistic contributing area was calculated using a Monte Carlo approach along with the calibrated model. The Monte Carlo simulation was done, using the parameter variance/covariance matrix generated by the regression model, to estimate probabilities associated with the contributing area to the wells. The probabilities arise from uncertainty in the estimated parameter values, which in turn arise from the adequacy of the data available to comprehensively describe the groundwater-flow sy

  11. Ionosphere Profile Estimation Using Ionosonde & GPS Data in an Inverse Refraction Calculation

    NASA Astrophysics Data System (ADS)

    Psiaki, M. L.

    2014-12-01

    A method has been developed to assimilate ionosonde virtual heights and GPS slant TEC data to estimate the parameters of a local ionosphere model, including estimates of the topside and of latitude and longitude variations. This effort seeks to better assimilate a variety of remote sensing data in order to characterize local (and eventually regional and global) ionosphere electron density profiles. The core calculations involve a forward refractive ray-tracing solution and a nonlinear optimal estimation algorithm that inverts the forward model. The ray-tracing calculations solve a nonlinear two-point boundary value problem for the curved ionosonde or GPS ray path through a parameterized electron density profile. It implements a full 3D solution that can handle the case of a tilted ionosphere. These calculations use Hamiltonian equivalents of the Appleton-Hartree magneto-plasma refraction index model. The current ionosphere parameterization is a modified Booker profile. It has been augmented to include latitude and longitude dependencies. The forward ray-tracing solution yields a given signal's group delay and beat carrier phase observables. An auxiliary set of boundary value problem solutions determine the sensitivities of the ray paths and observables with respect to the parameters of the augmented Booker profile. The nonlinear estimation algorithm compares the measured ionosonde virtual-altitude observables and GPS slant-TEC observables to the corresponding values from the forward refraction model. It uses the parameter sensitivities of the model to iteratively improve its parameter estimates in a way the reduces the residual errors between the measurements and their modeled values. This method has been applied to data from HAARP in Gakona, AK and has produced good TEC and virtual height fits. It has been extended to characterize electron density perturbations caused by HAARP heating experiments through the use of GPS slant TEC data for an LOS through the heated zone. The next planned extension of the method is to estimate the parameters of a regional ionosphere profile. The input observables will be slant TEC from an array of GPS receivers and group delay and carrier phase observables from an array of high-frequency beacons. The beacon array will function as a sort of multi-static ionosonde.

  12. Mechanistic analysis of multi-omics datasets to generate kinetic parameters for constraint-based metabolic models.

    PubMed

    Cotten, Cameron; Reed, Jennifer L

    2013-01-30

    Constraint-based modeling uses mass balances, flux capacity, and reaction directionality constraints to predict fluxes through metabolism. Although transcriptional regulation and thermodynamic constraints have been integrated into constraint-based modeling, kinetic rate laws have not been extensively used. In this study, an in vivo kinetic parameter estimation problem was formulated and solved using multi-omic data sets for Escherichia coli. To narrow the confidence intervals for kinetic parameters, a series of kinetic model simplifications were made, resulting in fewer kinetic parameters than the full kinetic model. These new parameter values are able to account for flux and concentration data from 20 different experimental conditions used in our training dataset. Concentration estimates from the simplified kinetic model were within one standard deviation for 92.7% of the 790 experimental measurements in the training set. Gibbs free energy changes of reaction were calculated to identify reactions that were often operating close to or far from equilibrium. In addition, enzymes whose activities were positively or negatively influenced by metabolite concentrations were also identified. The kinetic model was then used to calculate the maximum and minimum possible flux values for individual reactions from independent metabolite and enzyme concentration data that were not used to estimate parameter values. Incorporating these kinetically-derived flux limits into the constraint-based metabolic model improved predictions for uptake and secretion rates and intracellular fluxes in constraint-based models of central metabolism. This study has produced a method for in vivo kinetic parameter estimation and identified strategies and outcomes of kinetic model simplification. We also have illustrated how kinetic constraints can be used to improve constraint-based model predictions for intracellular fluxes and biomass yield and identify potential metabolic limitations through the integrated analysis of multi-omics datasets.

  13. Mechanistic analysis of multi-omics datasets to generate kinetic parameters for constraint-based metabolic models

    PubMed Central

    2013-01-01

    Background Constraint-based modeling uses mass balances, flux capacity, and reaction directionality constraints to predict fluxes through metabolism. Although transcriptional regulation and thermodynamic constraints have been integrated into constraint-based modeling, kinetic rate laws have not been extensively used. Results In this study, an in vivo kinetic parameter estimation problem was formulated and solved using multi-omic data sets for Escherichia coli. To narrow the confidence intervals for kinetic parameters, a series of kinetic model simplifications were made, resulting in fewer kinetic parameters than the full kinetic model. These new parameter values are able to account for flux and concentration data from 20 different experimental conditions used in our training dataset. Concentration estimates from the simplified kinetic model were within one standard deviation for 92.7% of the 790 experimental measurements in the training set. Gibbs free energy changes of reaction were calculated to identify reactions that were often operating close to or far from equilibrium. In addition, enzymes whose activities were positively or negatively influenced by metabolite concentrations were also identified. The kinetic model was then used to calculate the maximum and minimum possible flux values for individual reactions from independent metabolite and enzyme concentration data that were not used to estimate parameter values. Incorporating these kinetically-derived flux limits into the constraint-based metabolic model improved predictions for uptake and secretion rates and intracellular fluxes in constraint-based models of central metabolism. Conclusions This study has produced a method for in vivo kinetic parameter estimation and identified strategies and outcomes of kinetic model simplification. We also have illustrated how kinetic constraints can be used to improve constraint-based model predictions for intracellular fluxes and biomass yield and identify potential metabolic limitations through the integrated analysis of multi-omics datasets. PMID:23360254

  14. Estimating model parameters for an impact-produced shock-wave simulation: Optimal use of partial data with the extended Kalman filter

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kao, Jim; Flicker, Dawn; Ide, Kayo

    2006-05-20

    This paper builds upon our recent data assimilation work with the extended Kalman filter (EKF) method [J. Kao, D. Flicker, R. Henninger, S. Frey, M. Ghil, K. Ide, Data assimilation with an extended Kalman filter for an impact-produced shock-wave study, J. Comp. Phys. 196 (2004) 705-723.]. The purpose is to test the capability of EKF in optimizing a model's physical parameters. The problem is to simulate the evolution of a shock produced through a high-speed flyer plate. In the earlier work, we have showed that the EKF allows one to estimate the evolving state of the shock wave from amore » single pressure measurement, assuming that all model parameters are known. In the present paper, we show that imperfectly known model parameters can also be estimated accordingly, along with the evolving model state, from the same single measurement. The model parameter optimization using the EKF can be achieved through a simple modification of the original EKF formalism by including the model parameters into an augmented state variable vector. While the regular state variables are governed by both deterministic and stochastic forcing mechanisms, the parameters are only subject to the latter. The optimally estimated model parameters are thus obtained through a unified assimilation operation. We show that improving the accuracy of the model parameters also improves the state estimate. The time variation of the optimized model parameters results from blending the data and the corresponding values generated from the model and lies within a small range, of less than 2%, from the parameter values of the original model. The solution computed with the optimized parameters performs considerably better and has a smaller total variance than its counterpart using the original time-constant parameters. These results indicate that the model parameters play a dominant role in the performance of the shock-wave hydrodynamic code at hand.« less

  15. Markov Chain Monte Carlo Used in Parameter Inference of Magnetic Resonance Spectra

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hock, Kiel; Earle, Keith

    2016-02-06

    In this paper, we use Boltzmann statistics and the maximum likelihood distribution derived from Bayes’ Theorem to infer parameter values for a Pake Doublet Spectrum, a lineshape of historical significance and contemporary relevance for determining distances between interacting magnetic dipoles. A Metropolis Hastings Markov Chain Monte Carlo algorithm is implemented and designed to find the optimum parameter set and to estimate parameter uncertainties. In conclusion, the posterior distribution allows us to define a metric on parameter space that induces a geometry with negative curvature that affects the parameter uncertainty estimates, particularly for spectra with low signal to noise.

  16. Use of an anaerobic sequencing batch reactor for parameter estimation in modelling of anaerobic digestion.

    PubMed

    Batstone, D J; Torrijos, M; Ruiz, C; Schmidt, J E

    2004-01-01

    The model structure in anaerobic digestion has been clarified following publication of the IWA Anaerobic Digestion Model No. 1 (ADM1). However, parameter values are not well known, and uncertainty and variability in the parameter values given is almost unknown. Additionally, platforms for identification of parameters, namely continuous-flow laboratory digesters, and batch tests suffer from disadvantages such as long run times, and difficulty in defining initial conditions, respectively. Anaerobic sequencing batch reactors (ASBRs) are sequenced into fill-react-settle-decant phases, and offer promising possibilities for estimation of parameters, as they are by nature, dynamic in behaviour, and allow repeatable behaviour to establish initial conditions, and evaluate parameters. In this study, we estimated parameters describing winery wastewater (most COD as ethanol) degradation using data from sequencing operation, and validated these parameters using unsequenced pulses of ethanol and acetate. The model used was the ADM1, with an extension for ethanol degradation. Parameter confidence spaces were found by non-linear, correlated analysis of the two main Monod parameters; maximum uptake rate (k(m)), and half saturation concentration (K(S)). These parameters could be estimated together using only the measured acetate concentration (20 points per cycle). From interpolating the single cycle acetate data to multiple cycles, we estimate that a practical "optimal" identifiability could be achieved after two cycles for the acetate parameters, and three cycles for the ethanol parameters. The parameters found performed well in the short term, and represented the pulses of acetate and ethanol (within 4 days of the winery-fed cycles) very well. The main discrepancy was poor prediction of pH dynamics, which could be due to an unidentified buffer with an overall influence the same as a weak base (possibly CaCO3). Based on this work, ASBR systems are effective for parameter estimation, especially for comparative wastewater characterisation. The main disadvantages are heavy computational requirements for multiple cycles, and difficulty in establishing the correct biomass concentration in the reactor, though the last is also a disadvantage for continuous fixed film reactors, and especially, batch tests.

  17. Automatic parameter selection for feature-based multi-sensor image registration

    NASA Astrophysics Data System (ADS)

    DelMarco, Stephen; Tom, Victor; Webb, Helen; Chao, Alan

    2006-05-01

    Accurate image registration is critical for applications such as precision targeting, geo-location, change-detection, surveillance, and remote sensing. However, the increasing volume of image data is exceeding the current capacity of human analysts to perform manual registration. This image data glut necessitates the development of automated approaches to image registration, including algorithm parameter value selection. Proper parameter value selection is crucial to the success of registration techniques. The appropriate algorithm parameters can be highly scene and sensor dependent. Therefore, robust algorithm parameter value selection approaches are a critical component of an end-to-end image registration algorithm. In previous work, we developed a general framework for multisensor image registration which includes feature-based registration approaches. In this work we examine the problem of automated parameter selection. We apply the automated parameter selection approach of Yitzhaky and Peli to select parameters for feature-based registration of multisensor image data. The approach consists of generating multiple feature-detected images by sweeping over parameter combinations and using these images to generate estimated ground truth. The feature-detected images are compared to the estimated ground truth images to generate ROC points associated with each parameter combination. We develop a strategy for selecting the optimal parameter set by choosing the parameter combination corresponding to the optimal ROC point. We present numerical results showing the effectiveness of the approach using registration of collected SAR data to reference EO data.

  18. Evaluating alternate models to estimate genetic parameters of calving traits in United Kingdom Holstein-Friesian dairy cattle.

    PubMed

    Eaglen, Sophie A E; Coffey, Mike P; Woolliams, John A; Wall, Eileen

    2012-07-28

    The focus in dairy cattle breeding is gradually shifting from production to functional traits and genetic parameters of calving traits are estimated more frequently. However, across countries, various statistical models are used to estimate these parameters. This study evaluates different models for calving ease and stillbirth in United Kingdom Holstein-Friesian cattle. Data from first and later parity records were used. Genetic parameters for calving ease, stillbirth and gestation length were estimated using the restricted maximum likelihood method, considering different models i.e. sire (-maternal grandsire), animal, univariate and bivariate models. Gestation length was fitted as a correlated indicator trait and, for all three traits, genetic correlations between first and later parities were estimated. Potential bias in estimates was avoided by acknowledging a possible environmental direct-maternal covariance. The total heritable variance was estimated for each trait to discuss its theoretical importance and practical value. Prediction error variances and accuracies were calculated to compare the models. On average, direct and maternal heritabilities for calving traits were low, except for direct gestation length. Calving ease in first parity had a significant and negative direct-maternal genetic correlation. Gestation length was maternally correlated to stillbirth in first parity and directly correlated to calving ease in later parities. Multi-trait models had a slightly greater predictive ability than univariate models, especially for the lowly heritable traits. The computation time needed for sire (-maternal grandsire) models was much smaller than for animal models with only small differences in accuracy. The sire (-maternal grandsire) model was robust when additional genetic components were estimated, while the equivalent animal model had difficulties reaching convergence. For the evaluation of calving traits, multi-trait models show a slight advantage over univariate models. Extended sire models (-maternal grandsire) are more practical and robust than animal models. Estimated genetic parameters for calving traits of UK Holstein cattle are consistent with literature. Calculating an aggregate estimated breeding value including direct and maternal values should encourage breeders to consider both direct and maternal effects in selection decisions.

  19. Evaluating alternate models to estimate genetic parameters of calving traits in United Kingdom Holstein-Friesian dairy cattle

    PubMed Central

    2012-01-01

    Background The focus in dairy cattle breeding is gradually shifting from production to functional traits and genetic parameters of calving traits are estimated more frequently. However, across countries, various statistical models are used to estimate these parameters. This study evaluates different models for calving ease and stillbirth in United Kingdom Holstein-Friesian cattle. Methods Data from first and later parity records were used. Genetic parameters for calving ease, stillbirth and gestation length were estimated using the restricted maximum likelihood method, considering different models i.e. sire (−maternal grandsire), animal, univariate and bivariate models. Gestation length was fitted as a correlated indicator trait and, for all three traits, genetic correlations between first and later parities were estimated. Potential bias in estimates was avoided by acknowledging a possible environmental direct-maternal covariance. The total heritable variance was estimated for each trait to discuss its theoretical importance and practical value. Prediction error variances and accuracies were calculated to compare the models. Results and discussion On average, direct and maternal heritabilities for calving traits were low, except for direct gestation length. Calving ease in first parity had a significant and negative direct-maternal genetic correlation. Gestation length was maternally correlated to stillbirth in first parity and directly correlated to calving ease in later parities. Multi-trait models had a slightly greater predictive ability than univariate models, especially for the lowly heritable traits. The computation time needed for sire (−maternal grandsire) models was much smaller than for animal models with only small differences in accuracy. The sire (−maternal grandsire) model was robust when additional genetic components were estimated, while the equivalent animal model had difficulties reaching convergence. Conclusions For the evaluation of calving traits, multi-trait models show a slight advantage over univariate models. Extended sire models (−maternal grandsire) are more practical and robust than animal models. Estimated genetic parameters for calving traits of UK Holstein cattle are consistent with literature. Calculating an aggregate estimated breeding value including direct and maternal values should encourage breeders to consider both direct and maternal effects in selection decisions. PMID:22839757

  20. Recovering Parameters of Johnson's SB Distribution

    Treesearch

    Bernard R. Parresol

    2003-01-01

    A new parameter recovery model for Johnson's SB distribution is developed. This latest alternative approach permits recovery of the range and both shape parameters. Previous models recovered only the two shape parameters. Also, a simple procedure for estimating the distribution minimum from sample values is presented. The new methodology...

  1. Combined Parameter and State Estimation Problem in a Complex Domain: RF Hyperthermia Treatment Using Nanoparticles

    NASA Astrophysics Data System (ADS)

    Bermeo Varon, L. A.; Orlande, H. R. B.; Eliçabe, G. E.

    2016-09-01

    The particle filter methods have been widely used to solve inverse problems with sequential Bayesian inference in dynamic models, simultaneously estimating sequential state variables and fixed model parameters. This methods are an approximation of sequences of probability distributions of interest, that using a large set of random samples, with presence uncertainties in the model, measurements and parameters. In this paper the main focus is the solution combined parameters and state estimation in the radiofrequency hyperthermia with nanoparticles in a complex domain. This domain contains different tissues like muscle, pancreas, lungs, small intestine and a tumor which is loaded iron oxide nanoparticles. The results indicated that excellent agreements between estimated and exact value are obtained.

  2. The Use of One-Sample Prediction Intervals for Estimating CO2 Scrubber Canister Durations

    DTIC Science & Technology

    2012-10-01

    Grade and 812 D-Grade Sofnolime.3 Definitions According to Devore,4 A CI (confidence interval) refers to a parameter, or population ... characteristic , whose value is fixed but unknown to us. In contrast, a future value of Y is not a parameter but instead a random variable; for this

  3. An improved method for predicting the evolution of the characteristic parameters of an information system

    NASA Astrophysics Data System (ADS)

    Dushkin, A. V.; Kasatkina, T. I.; Novoseltsev, V. I.; Ivanov, S. V.

    2018-03-01

    The article proposes a forecasting method that allows, based on the given values of entropy and error level of the first and second kind, to determine the allowable time for forecasting the development of the characteristic parameters of a complex information system. The main feature of the method under consideration is the determination of changes in the characteristic parameters of the development of the information system in the form of the magnitude of the increment in the ratios of its entropy. When a predetermined value of the prediction error ratio is reached, that is, the entropy of the system, the characteristic parameters of the system and the depth of the prediction in time are estimated. The resulting values of the characteristics and will be optimal, since at that moment the system possessed the best ratio of entropy as a measure of the degree of organization and orderliness of the structure of the system. To construct a method for estimating the depth of prediction, it is expedient to use the maximum principle of the value of entropy.

  4. Estimating varying coefficients for partial differential equation models.

    PubMed

    Zhang, Xinyu; Cao, Jiguo; Carroll, Raymond J

    2017-09-01

    Partial differential equations (PDEs) are used to model complex dynamical systems in multiple dimensions, and their parameters often have important scientific interpretations. In some applications, PDE parameters are not constant but can change depending on the values of covariates, a feature that we call varying coefficients. We propose a parameter cascading method to estimate varying coefficients in PDE models from noisy data. Our estimates of the varying coefficients are shown to be consistent and asymptotically normally distributed. The performance of our method is evaluated by a simulation study and by an empirical study estimating three varying coefficients in a PDE model arising from LIDAR data. © 2017, The International Biometric Society.

  5. Probable flood predictions in ungauged coastal basins of El Salvador

    USGS Publications Warehouse

    Friedel, M.J.; Smith, M.E.; Chica, A.M.E.; Litke, D.

    2008-01-01

    A regionalization procedure is presented and used to predict probable flooding in four ungauged coastal river basins of El Salvador: Paz, Jiboa, Grande de San Miguel, and Goascoran. The flood-prediction problem is sequentially solved for two regions: upstream mountains and downstream alluvial plains. In the upstream mountains, a set of rainfall-runoff parameter values and recurrent peak-flow discharge hydrographs are simultaneously estimated for 20 tributary-basin models. Application of dissimilarity equations among tributary basins (soft prior information) permitted development of a parsimonious parameter structure subject to information content in the recurrent peak-flow discharge values derived using regression equations based on measurements recorded outside the ungauged study basins. The estimated joint set of parameter values formed the basis from which probable minimum and maximum peak-flow discharge limits were then estimated revealing that prediction uncertainty increases with basin size. In the downstream alluvial plain, model application of the estimated minimum and maximum peak-flow hydrographs facilitated simulation of probable 100-year flood-flow depths in confined canyons and across unconfined coastal alluvial plains. The regionalization procedure provides a tool for hydrologic risk assessment and flood protection planning that is not restricted to the case presented herein. ?? 2008 ASCE.

  6. Weak Value Amplification is Suboptimal for Estimation and Detection

    NASA Astrophysics Data System (ADS)

    Ferrie, Christopher; Combes, Joshua

    2014-01-01

    We show by using statistically rigorous arguments that the technique of weak value amplification does not perform better than standard statistical techniques for the tasks of single parameter estimation and signal detection. Specifically, we prove that postselection, a necessary ingredient for weak value amplification, decreases estimation accuracy and, moreover, arranging for anomalously large weak values is a suboptimal strategy. In doing so, we explicitly provide the optimal estimator, which in turn allows us to identify the optimal experimental arrangement to be the one in which all outcomes have equal weak values (all as small as possible) and the initial state of the meter is the maximal eigenvalue of the square of the system observable. Finally, we give precise quantitative conditions for when weak measurement (measurements without postselection or anomalously large weak values) can mitigate the effect of uncharacterized technical noise in estimation.

  7. New Insights into the Estimation of Extreme Geomagnetic Storm Occurrences

    NASA Astrophysics Data System (ADS)

    Ruffenach, Alexis; Winter, Hugo; Lavraud, Benoit; Bernardara, Pietro

    2017-04-01

    Space weather events such as intense geomagnetic storms are major disturbances of the near-Earth environment that may lead to serious impacts on our modern society. As such, it is of great importance to estimate their probability, and in particular that of extreme events. One approach largely used in statistical sciences for extreme events probability estimates is Extreme Value Analysis (EVA). Using this rigorous statistical framework, estimations of the occurrence of extreme geomagnetic storms are performed here based on the most relevant global parameters related to geomagnetic storms, such as ground parameters (e.g. geomagnetic Dst and aa indexes), and space parameters related to the characteristics of Coronal Mass Ejections (CME) (velocity, southward magnetic field component, electric field). Using our fitted model, we estimate the annual probability of a Carrington-type event (Dst = -850nT) to be on the order of 10-3, with a lower limit of the uncertainties on the return period of ˜500 years. Our estimate is significantly higher than that of most past studies, which typically had a return period of a few 100 years at maximum. Thus precautions are required when extrapolating intense values. Currently, the complexity of the processes and the length of available data inevitably leads to significant uncertainties in return period estimates for the occurrence of extreme geomagnetic storms. However, our application of extreme value models for extrapolating into the tail of the distribution provides a mathematically justified framework for the estimation of extreme return periods, thereby enabling the determination of more accurate estimates and reduced associated uncertainties.

  8. Statistical inference involving binomial and negative binomial parameters.

    PubMed

    García-Pérez, Miguel A; Núñez-Antón, Vicente

    2009-05-01

    Statistical inference about two binomial parameters implies that they are both estimated by binomial sampling. There are occasions in which one aims at testing the equality of two binomial parameters before and after the occurrence of the first success along a sequence of Bernoulli trials. In these cases, the binomial parameter before the first success is estimated by negative binomial sampling whereas that after the first success is estimated by binomial sampling, and both estimates are related. This paper derives statistical tools to test two hypotheses, namely, that both binomial parameters equal some specified value and that both parameters are equal though unknown. Simulation studies are used to show that in small samples both tests are accurate in keeping the nominal Type-I error rates, and also to determine sample size requirements to detect large, medium, and small effects with adequate power. Additional simulations also show that the tests are sufficiently robust to certain violations of their assumptions.

  9. Coupling heat and chemical tracer experiments for estimating heat transfer parameters in shallow alluvial aquifers.

    PubMed

    Wildemeersch, S; Jamin, P; Orban, P; Hermans, T; Klepikova, M; Nguyen, F; Brouyère, S; Dassargues, A

    2014-11-15

    Geothermal energy systems, closed or open, are increasingly considered for heating and/or cooling buildings. The efficiency of such systems depends on the thermal properties of the subsurface. Therefore, feasibility and impact studies performed prior to their installation should include a field characterization of thermal properties and a heat transfer model using parameter values measured in situ. However, there is a lack of in situ experiments and methodology for performing such a field characterization, especially for open systems. This study presents an in situ experiment designed for estimating heat transfer parameters in shallow alluvial aquifers with focus on the specific heat capacity. This experiment consists in simultaneously injecting hot water and a chemical tracer into the aquifer and monitoring the evolution of groundwater temperature and concentration in the recovery well (and possibly in other piezometers located down gradient). Temperature and concentrations are then used for estimating the specific heat capacity. The first method for estimating this parameter is based on a modeling in series of the chemical tracer and temperature breakthrough curves at the recovery well. The second method is based on an energy balance. The values of specific heat capacity estimated for both methods (2.30 and 2.54MJ/m(3)/K) for the experimental site in the alluvial aquifer of the Meuse River (Belgium) are almost identical and consistent with values found in the literature. Temperature breakthrough curves in other piezometers are not required for estimating the specific heat capacity. However, they highlight that heat transfer in the alluvial aquifer of the Meuse River is complex and contrasted with different dominant process depending on the depth leading to significant vertical heat exchange between upper and lower part of the aquifer. Furthermore, these temperature breakthrough curves could be included in the calibration of a complex heat transfer model for estimating the entire set of heat transfer parameters and their spatial distribution by inverse modeling. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. PREVALENCE OF METABOLIC SYNDROME IN YOUNG MEXICANS: A SENSITIVITY ANALYSIS ON ITS COMPONENTS.

    PubMed

    Murguía-Romero, Miguel; Jiménez-Flores, J Rafael; Sigrist-Flores, Santiago C; Tapia-Pancardo, Diana C; Jiménez-Ramos, Arnulfo; Méndez-Cruz, A René; Villalobos-Molina, Rafael

    2015-07-28

    obesity is a worldwide epidemic, and the high prevalence of diabetes type II (DM2) and cardiovascular disease (CVD) is in great part a consequence of that epidemic. Metabolic syndrome is a useful tool to estimate the risk of a young population to evolve to DM2 and CVD. to estimate the MetS prevalence in young Mexicans, and to evaluate each parameter as an independent indicator through a sensitivity analysis. the prevalence of MetS was estimated in 6 063 young of the México City metropolitan area. A sensitivity analysis was conducted to estimate the performance of each one of the components of MetS, as an indicator of the presence of MetS itself. Five statistical of the sensitivity analysis were calculated for each MetS component and the other parameters included: sensitivity, specificity, positive predictive value or precision, negative predictive value, and accuracy. the prevalence of MetS in Mexican young population was estimated to be 13.4%. Waist circumference presented the highest sensitivity (96.8% women; 90.0% men), blood pressure presented the highest specificity for women (97.7%) and glucose for men (91.0%). When all the five statistical are considered triglycerides is the component with the highest values, showing a value of 75% or more in four of them. Differences by sex are detected for averages of all components of MetS in young without alterations. Mexican young are highly prone to acquire MetS: 71% have at least one and up to five MetS parameters altered, and 13.4% of them have MetS. From all the five components of MetS, waist circumference presented the highest sensitivity as a predictor of MetS, and triglycerides is the best parameter if a single factor is to be taken as sole predictor of MetS in Mexican young population, triglycerides is also the parameter with the highest accuracy. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  11. Uncertainties of flood frequency estimation approaches based on continuous simulation using data resampling

    NASA Astrophysics Data System (ADS)

    Arnaud, Patrick; Cantet, Philippe; Odry, Jean

    2017-11-01

    Flood frequency analyses (FFAs) are needed for flood risk management. Many methods exist ranging from classical purely statistical approaches to more complex approaches based on process simulation. The results of these methods are associated with uncertainties that are sometimes difficult to estimate due to the complexity of the approaches or the number of parameters, especially for process simulation. This is the case of the simulation-based FFA approach called SHYREG presented in this paper, in which a rainfall generator is coupled with a simple rainfall-runoff model in an attempt to estimate the uncertainties due to the estimation of the seven parameters needed to estimate flood frequencies. The six parameters of the rainfall generator are mean values, so their theoretical distribution is known and can be used to estimate the generator uncertainties. In contrast, the theoretical distribution of the single hydrological model parameter is unknown; consequently, a bootstrap method is applied to estimate the calibration uncertainties. The propagation of uncertainty from the rainfall generator to the hydrological model is also taken into account. This method is applied to 1112 basins throughout France. Uncertainties coming from the SHYREG method and from purely statistical approaches are compared, and the results are discussed according to the length of the recorded observations, basin size and basin location. Uncertainties of the SHYREG method decrease as the basin size increases or as the length of the recorded flow increases. Moreover, the results show that the confidence intervals of the SHYREG method are relatively small despite the complexity of the method and the number of parameters (seven). This is due to the stability of the parameters and takes into account the dependence of uncertainties due to the rainfall model and the hydrological calibration. Indeed, the uncertainties on the flow quantiles are on the same order of magnitude as those associated with the use of a statistical law with two parameters (here generalised extreme value Type I distribution) and clearly lower than those associated with the use of a three-parameter law (here generalised extreme value Type II distribution). For extreme flood quantiles, the uncertainties are mostly due to the rainfall generator because of the progressive saturation of the hydrological model.

  12. Reference-free error estimation for multiple measurement methods.

    PubMed

    Madan, Hennadii; Pernuš, Franjo; Špiclin, Žiga

    2018-01-01

    We present a computational framework to select the most accurate and precise method of measurement of a certain quantity, when there is no access to the true value of the measurand. A typical use case is when several image analysis methods are applied to measure the value of a particular quantitative imaging biomarker from the same images. The accuracy of each measurement method is characterized by systematic error (bias), which is modeled as a polynomial in true values of measurand, and the precision as random error modeled with a Gaussian random variable. In contrast to previous works, the random errors are modeled jointly across all methods, thereby enabling the framework to analyze measurement methods based on similar principles, which may have correlated random errors. Furthermore, the posterior distribution of the error model parameters is estimated from samples obtained by Markov chain Monte-Carlo and analyzed to estimate the parameter values and the unknown true values of the measurand. The framework was validated on six synthetic and one clinical dataset containing measurements of total lesion load, a biomarker of neurodegenerative diseases, which was obtained with four automatic methods by analyzing brain magnetic resonance images. The estimates of bias and random error were in a good agreement with the corresponding least squares regression estimates against a reference.

  13. Regional evaporation estimates in the eastern monsoon region of China: Assessment of a nonlinear formulation of the complementary principle

    NASA Astrophysics Data System (ADS)

    Liu, Xiaomang; Liu, Changming; Brutsaert, Wilfried

    2016-12-01

    The performance of a nonlinear formulation of the complementary principle for evaporation estimation was investigated in 241 catchments with different climate conditions in the eastern monsoon region of China. Evaporation (Ea) calculated by the water balance equation was used as the reference. Ea estimated by the calibrated nonlinear formulation was generally in good agreement with the water balance results, especially in relatively dry catchments. The single parameter in the nonlinear formulation, namely αe as a weak analog of the alpha parameter of Priestley and Taylor (), tended to exhibit larger values in warmer and humid near-coastal areas, but smaller values in colder, drier environments inland, with a significant dependency on the aridity index (AI). The nonlinear formulation combined with the equation relating the one parameter and AI provides a promising method to estimate regional Ea with standard and routinely measured meteorological data.

  14. HIV Model Parameter Estimates from Interruption Trial Data including Drug Efficacy and Reservoir Dynamics

    PubMed Central

    Luo, Rutao; Piovoso, Michael J.; Martinez-Picado, Javier; Zurakowski, Ryan

    2012-01-01

    Mathematical models based on ordinary differential equations (ODE) have had significant impact on understanding HIV disease dynamics and optimizing patient treatment. A model that characterizes the essential disease dynamics can be used for prediction only if the model parameters are identifiable from clinical data. Most previous parameter identification studies for HIV have used sparsely sampled data from the decay phase following the introduction of therapy. In this paper, model parameters are identified from frequently sampled viral-load data taken from ten patients enrolled in the previously published AutoVac HAART interruption study, providing between 69 and 114 viral load measurements from 3–5 phases of viral decay and rebound for each patient. This dataset is considerably larger than those used in previously published parameter estimation studies. Furthermore, the measurements come from two separate experimental conditions, which allows for the direct estimation of drug efficacy and reservoir contribution rates, two parameters that cannot be identified from decay-phase data alone. A Markov-Chain Monte-Carlo method is used to estimate the model parameter values, with initial estimates obtained using nonlinear least-squares methods. The posterior distributions of the parameter estimates are reported and compared for all patients. PMID:22815727

  15. Estimation of some transducer parameters in a broadband piezoelectric transmitter by using an artificial intelligence technique.

    PubMed

    Ruíz, A; Ramos, A; San Emeterio, J L

    2004-04-01

    An estimation procedure to efficiently find approximate values of internal parameters in ultrasonic transducers intended for broadband operation would be a valuable tool to discover internal construction data. This information is necessary in the modelling and simulation of acoustic and electrical behaviour related to ultrasonic systems containing commercial transducers. There is not a general solution for this generic problem of parameter estimation in the case of broadband piezoelectric probes. In this paper, this general problem is briefly analysed for broadband conditions. The viability of application in this field of an artificial intelligence technique supported on the modelling of the transducer internal components is studied. A genetic algorithm (GA) procedure is presented and applied to the estimation of different parameters, related to two transducers which are working as pulsed transmitters. The efficiency of this GA technique is studied, considering the influence of the number and variation range of the estimated parameters. Estimation results are experimentally ratified.

  16. Evaluation of optimized b-value sampling schemas for diffusion kurtosis imaging with an application to stroke patient data

    PubMed Central

    Yan, Xu; Zhou, Minxiong; Ying, Lingfang; Yin, Dazhi; Fan, Mingxia; Yang, Guang; Zhou, Yongdi; Song, Fan; Xu, Dongrong

    2013-01-01

    Diffusion kurtosis imaging (DKI) is a new method of magnetic resonance imaging (MRI) that provides non-Gaussian information that is not available in conventional diffusion tensor imaging (DTI). DKI requires data acquisition at multiple b-values for parameter estimation; this process is usually time-consuming. Therefore, fewer b-values are preferable to expedite acquisition. In this study, we carefully evaluated various acquisition schemas using different numbers and combinations of b-values. Acquisition schemas that sampled b-values that were distributed to two ends were optimized. Compared to conventional schemas using equally spaced b-values (ESB), optimized schemas require fewer b-values to minimize fitting errors in parameter estimation and may thus significantly reduce scanning time. Following a ranked list of optimized schemas resulted from the evaluation, we recommend the 3b schema based on its estimation accuracy and time efficiency, which needs data from only 3 b-values at 0, around 800 and around 2600 s/mm2, respectively. Analyses using voxel-based analysis (VBA) and region-of-interest (ROI) analysis with human DKI datasets support the use of the optimized 3b (0, 1000, 2500 s/mm2) DKI schema in practical clinical applications. PMID:23735303

  17. Estimating recharge rates with analytic element models and parameter estimation

    USGS Publications Warehouse

    Dripps, W.R.; Hunt, R.J.; Anderson, M.P.

    2006-01-01

    Quantifying the spatial and temporal distribution of recharge is usually a prerequisite for effective ground water flow modeling. In this study, an analytic element (AE) code (GFLOW) was used with a nonlinear parameter estimation code (UCODE) to quantify the spatial and temporal distribution of recharge using measured base flows as calibration targets. The ease and flexibility of AE model construction and evaluation make this approach well suited for recharge estimation. An AE flow model of an undeveloped watershed in northern Wisconsin was optimized to match median annual base flows at four stream gages for 1996 to 2000 to demonstrate the approach. Initial optimizations that assumed a constant distributed recharge rate provided good matches (within 5%) to most of the annual base flow estimates, but discrepancies of >12% at certain gages suggested that a single value of recharge for the entire watershed is inappropriate. Subsequent optimizations that allowed for spatially distributed recharge zones based on the distribution of vegetation types improved the fit and confirmed that vegetation can influence spatial recharge variability in this watershed. Temporally, the annual recharge values varied >2.5-fold between 1996 and 2000 during which there was an observed 1.7-fold difference in annual precipitation, underscoring the influence of nonclimatic factors on interannual recharge variability for regional flow modeling. The final recharge values compared favorably with more labor-intensive field measurements of recharge and results from studies, supporting the utility of using linked AE-parameter estimation codes for recharge estimation. Copyright ?? 2005 The Author(s).

  18. Implicit assimilation for marine ecological models

    NASA Astrophysics Data System (ADS)

    Weir, B.; Miller, R.; Spitz, Y. H.

    2012-12-01

    We use a new data assimilation method to estimate the parameters of a marine ecological model. At a given point in the ocean, the estimated values of the parameters determine the behaviors of the modeled planktonic groups, and thus indicate which species are dominant. To begin, we assimilate in situ observations, e.g., the Bermuda Atlantic Time-series Study, the Hawaii Ocean Time-series, and Ocean Weather Station Papa. From there, we estimate the parameters at surrounding points in space based on satellite observations of ocean color. Given the variation of the estimated parameters, we divide the ocean into regions meant to represent distinct ecosystems. An important feature of the data assimilation approach is that it refines the confidence limits of the optimal Gaussian approximation to the distribution of the parameters. This enables us to determine the ecological divisions with greater accuracy.

  19. Model estimation of claim risk and premium for motor vehicle insurance by using Bayesian method

    NASA Astrophysics Data System (ADS)

    Sukono; Riaman; Lesmana, E.; Wulandari, R.; Napitupulu, H.; Supian, S.

    2018-01-01

    Risk models need to be estimated by the insurance company in order to predict the magnitude of the claim and determine the premiums charged to the insured. This is intended to prevent losses in the future. In this paper, we discuss the estimation of risk model claims and motor vehicle insurance premiums using Bayesian methods approach. It is assumed that the frequency of claims follow a Poisson distribution, while a number of claims assumed to follow a Gamma distribution. The estimation of parameters of the distribution of the frequency and amount of claims are made by using Bayesian methods. Furthermore, the estimator distribution of frequency and amount of claims are used to estimate the aggregate risk models as well as the value of the mean and variance. The mean and variance estimator that aggregate risk, was used to predict the premium eligible to be charged to the insured. Based on the analysis results, it is shown that the frequency of claims follow a Poisson distribution with parameter values λ is 5.827. While a number of claims follow the Gamma distribution with parameter values p is 7.922 and θ is 1.414. Therefore, the obtained values of the mean and variance of the aggregate claims respectively are IDR 32,667,489.88 and IDR 38,453,900,000,000.00. In this paper the prediction of the pure premium eligible charged to the insured is obtained, which amounting to IDR 2,722,290.82. The prediction of the claims and premiums aggregate can be used as a reference for the insurance company’s decision-making in management of reserves and premiums of motor vehicle insurance.

  20. Identifying Bearing Rotodynamic Coefficients Using an Extended Kalman Filter

    NASA Technical Reports Server (NTRS)

    Miller, Brad A.; Howard, Samuel A.

    2008-01-01

    An Extended Kalman Filter is developed to estimate the linearized direct and indirect stiffness and damping force coefficients for bearings in rotor dynamic applications from noisy measurements of the shaft displacement in response to imbalance and impact excitation. The bearing properties are modeled as stochastic random variables using a Gauss-Markov model. Noise terms are introduced into the system model to account for all of the estimation error, including modeling errors and uncertainties and the propagation of measurement errors into the parameter estimates. The system model contains two user-defined parameters that can be tuned to improve the filter's performance; these parameters correspond to the covariance of the system and measurement noise variables. The filter is also strongly influenced by the initial values of the states and the error covariance matrix. The filter is demonstrated using numerically simulated data for a rotor bearing system with two identical bearings, which reduces the number of unknown linear dynamic coefficients to eight. The filter estimates for the direct damping coefficients and all four stiffness coefficients correlated well with actual values, whereas the estimates for the cross-coupled damping coefficients were the least accurate.

  1. Linear least squares approach for evaluating crack tip fracture parameters using isochromatic and isoclinic data from digital photoelasticity

    NASA Astrophysics Data System (ADS)

    Patil, Prataprao; Vyasarayani, C. P.; Ramji, M.

    2017-06-01

    In this work, digital photoelasticity technique is used to estimate the crack tip fracture parameters for different crack configurations. Conventionally, only isochromatic data surrounding the crack tip is used for SIF estimation, but with the advent of digital photoelasticity, pixel-wise availability of both isoclinic and isochromatic data could be exploited for SIF estimation in a novel way. A linear least square approach is proposed to estimate the mixed-mode crack tip fracture parameters by solving the multi-parameter stress field equation. The stress intensity factor (SIF) is extracted from those estimated fracture parameters. The isochromatic and isoclinic data around the crack tip is estimated using the ten-step phase shifting technique. To get the unwrapped data, the adaptive quality guided phase unwrapping algorithm (AQGPU) has been used. The mixed mode fracture parameters, especially SIF are estimated for specimen configurations like single edge notch (SEN), center crack and straight crack ahead of inclusion using the proposed algorithm. The experimental SIF values estimated using the proposed method are compared with analytical/finite element analysis (FEA) results, and are found to be in good agreement.

  2. Subsonic flight test evaluation of a propulsion system parameter estimation process for the F100 engine

    NASA Technical Reports Server (NTRS)

    Orme, John S.; Gilyard, Glenn B.

    1992-01-01

    Integrated engine-airframe optimal control technology may significantly improve aircraft performance. This technology requires a reliable and accurate parameter estimator to predict unmeasured variables. To develop this technology base, NASA Dryden Flight Research Facility (Edwards, CA), McDonnell Aircraft Company (St. Louis, MO), and Pratt & Whitney (West Palm Beach, FL) have developed and flight-tested an adaptive performance seeking control system which optimizes the quasi-steady-state performance of the F-15 propulsion system. This paper presents flight and ground test evaluations of the propulsion system parameter estimation process used by the performance seeking control system. The estimator consists of a compact propulsion system model and an extended Kalman filter. The extended Laman filter estimates five engine component deviation parameters from measured inputs. The compact model uses measurements and Kalman-filter estimates as inputs to predict unmeasured propulsion parameters such as net propulsive force and fan stall margin. The ability to track trends and estimate absolute values of propulsion system parameters was demonstrated. For example, thrust stand results show a good correlation, especially in trends, between the performance seeking control estimated and measured thrust.

  3. A new Bayesian recursive technique for parameter estimation

    NASA Astrophysics Data System (ADS)

    Kaheil, Yasir H.; Gill, M. Kashif; McKee, Mac; Bastidas, Luis

    2006-08-01

    The performance of any model depends on how well its associated parameters are estimated. In the current application, a localized Bayesian recursive estimation (LOBARE) approach is devised for parameter estimation. The LOBARE methodology is an extension of the Bayesian recursive estimation (BARE) method. It is applied in this paper on two different types of models: an artificial intelligence (AI) model in the form of a support vector machine (SVM) application for forecasting soil moisture and a conceptual rainfall-runoff (CRR) model represented by the Sacramento soil moisture accounting (SAC-SMA) model. Support vector machines, based on statistical learning theory (SLT), represent the modeling task as a quadratic optimization problem and have already been used in various applications in hydrology. They require estimation of three parameters. SAC-SMA is a very well known model that estimates runoff. It has a 13-dimensional parameter space. In the LOBARE approach presented here, Bayesian inference is used in an iterative fashion to estimate the parameter space that will most likely enclose a best parameter set. This is done by narrowing the sampling space through updating the "parent" bounds based on their fitness. These bounds are actually the parameter sets that were selected by BARE runs on subspaces of the initial parameter space. The new approach results in faster convergence toward the optimal parameter set using minimum training/calibration data and fewer sets of parameter values. The efficacy of the localized methodology is also compared with the previously used BARE algorithm.

  4. Uncertainty Quantification of GEOS-5 L-band Radiative Transfer Model Parameters Using Bayesian Inference and SMOS Observations

    NASA Technical Reports Server (NTRS)

    DeLannoy, Gabrielle J. M.; Reichle, Rolf H.; Vrugt, Jasper A.

    2013-01-01

    Uncertainties in L-band (1.4 GHz) radiative transfer modeling (RTM) affect the simulation of brightness temperatures (Tb) over land and the inversion of satellite-observed Tb into soil moisture retrievals. In particular, accurate estimates of the microwave soil roughness, vegetation opacity and scattering albedo for large-scale applications are difficult to obtain from field studies and often lack an uncertainty estimate. Here, a Markov Chain Monte Carlo (MCMC) simulation method is used to determine satellite-scale estimates of RTM parameters and their posterior uncertainty by minimizing the misfit between long-term averages and standard deviations of simulated and observed Tb at a range of incidence angles, at horizontal and vertical polarization, and for morning and evening overpasses. Tb simulations are generated with the Goddard Earth Observing System (GEOS-5) and confronted with Tb observations from the Soil Moisture Ocean Salinity (SMOS) mission. The MCMC algorithm suggests that the relative uncertainty of the RTM parameter estimates is typically less than 25 of the maximum a posteriori density (MAP) parameter value. Furthermore, the actual root-mean-square-differences in long-term Tb averages and standard deviations are found consistent with the respective estimated total simulation and observation error standard deviations of m3.1K and s2.4K. It is also shown that the MAP parameter values estimated through MCMC simulation are in close agreement with those obtained with Particle Swarm Optimization (PSO).

  5. Parameter estimation in Probabilistic Seismic Hazard Analysis: current problems and some solutions

    NASA Astrophysics Data System (ADS)

    Vermeulen, Petrus

    2017-04-01

    A typical Probabilistic Seismic Hazard Analysis (PSHA) comprises identification of seismic source zones, determination of hazard parameters for these zones, selection of an appropriate ground motion prediction equation (GMPE), and integration over probabilities according the Cornell-McGuire procedure. Determination of hazard parameters often does not receive the attention it deserves, and, therefore, problems therein are often overlooked. Here, many of these problems are identified, and some of them addressed. The parameters that need to be identified are those associated with the frequency-magnitude law, those associated with earthquake recurrence law in time, and the parameters controlling the GMPE. This study is concerned with the frequency-magnitude law and temporal distribution of earthquakes, and not with GMPEs. TheGutenberg-Richter frequency-magnitude law is usually adopted for the frequency-magnitude law, and a Poisson process for earthquake recurrence in time. Accordingly, the parameters that need to be determined are the slope parameter of the Gutenberg-Richter frequency-magnitude law, i.e. the b-value, the maximum value at which the Gutenberg-Richter law applies mmax, and the mean recurrence frequency,λ, of earthquakes. If, instead of the Cornell-McGuire, the "Parametric-Historic procedure" is used, these parameters do not have to be known before the PSHA computations, they are estimated directly during the PSHA computation. The resulting relation for the frequency of ground motion vibration parameters has an analogous functional form to the frequency-magnitude law, which is described by parameters γ (analogous to the b¬-value of the Gutenberg-Richter law) and the maximum possible ground motion amax (analogous to mmax). Originally, the approach was possible to apply only to the simple GMPE, however, recently a method was extended to incorporate more complex forms of GMPE's. With regards to the parameter mmax, there are numerous methods of estimation, none of which is accepted as the standard one. There is also much controversy surrounding this parameter. In practice, when estimating the above mentioned parameters from seismic catalogue, the magnitude, mmin, from which a seismic catalogue is complete becomes important.Thus, the parameter mmin is also considered as a parameter to be estimated in practice. Several methods are discussed in the literature, and no specific method is preferred. Methods usually aim at identifying the point where a frequency-magnitude plot starts to deviate from linearity due to data loss. Parameter estimation is clearly a rich field which deserves much attention and, possibly standardization, of methods. These methods should be the sound and efficient, and a query into which methods are to be used - and for that matter which ones are not to be used - is in order.

  6. Maximum entropy approach to statistical inference for an ocean acoustic waveguide.

    PubMed

    Knobles, D P; Sagers, J D; Koch, R A

    2012-02-01

    A conditional probability distribution suitable for estimating the statistical properties of ocean seabed parameter values inferred from acoustic measurements is derived from a maximum entropy principle. The specification of the expectation value for an error function constrains the maximization of an entropy functional. This constraint determines the sensitivity factor (β) to the error function of the resulting probability distribution, which is a canonical form that provides a conservative estimate of the uncertainty of the parameter values. From the conditional distribution, marginal distributions for individual parameters can be determined from integration over the other parameters. The approach is an alternative to obtaining the posterior probability distribution without an intermediary determination of the likelihood function followed by an application of Bayes' rule. In this paper the expectation value that specifies the constraint is determined from the values of the error function for the model solutions obtained from a sparse number of data samples. The method is applied to ocean acoustic measurements taken on the New Jersey continental shelf. The marginal probability distribution for the values of the sound speed ratio at the surface of the seabed and the source levels of a towed source are examined for different geoacoustic model representations. © 2012 Acoustical Society of America

  7. Relative enhanced diffusivity: noise sensitivity, protocol optimization, and the relation to intravoxel incoherent motion.

    PubMed

    While, Peter T; Teruel, Jose R; Vidić, Igor; Bathen, Tone F; Goa, Pål Erik

    2018-06-01

    To explore the relationship between relative enhanced diffusivity (RED) and intravoxel incoherent motion (IVIM), as well as the impact of noise and the choice of intermediate diffusion weighting (b value) on the RED parameter. A mathematical derivation was performed to cast RED in terms of the IVIM parameters. Noise analysis and b value optimization was conducted by using Monte Carlo calculations to generate diffusion-weighted imaging data appropriate to breast and liver tissue at three different signal-to-noise ratios. RED was shown to be approximately linearly proportional to the IVIM parameter f, inversely proportional to D and to follow an inverse exponential decay with respect to D*. The choice of intermediate b value was shown to be important in minimizing the impact of noise on RED and in maximizing its discriminatory power. RED was shown to be essentially a reparameterization of the IVIM estimates for f and D obtained with three b values. RED imaging in the breast and liver should be performed with intermediate b values of 100 and 50 s/mm 2 , respectively. Future clinical studies involving RED should also estimate the IVIM parameters f and D using three b values for comparison.

  8. Robust linear parameter-varying control of blood pressure using vasoactive drugs

    NASA Astrophysics Data System (ADS)

    Luspay, Tamas; Grigoriadis, Karolos

    2015-10-01

    Resuscitation of emergency care patients requires fast restoration of blood pressure to a target value to achieve hemodynamic stability and vital organ perfusion. A robust control design methodology is presented in this paper for regulating the blood pressure of hypotensive patients by means of the closed-loop administration of vasoactive drugs. To this end, a dynamic first-order delay model is utilised to describe the vasoactive drug response with varying parameters that represent intra-patient and inter-patient variability. The proposed framework consists of two components: first, an online model parameter estimation is carried out using a multiple-model extended Kalman-filter. Second, the estimated model parameters are used for continuously scheduling a robust linear parameter-varying (LPV) controller. The closed-loop behaviour is characterised by parameter-varying dynamic weights designed to regulate the mean arterial pressure to a target value. Experimental data of blood pressure response of anesthetised pigs to phenylephrine injection are used for validating the LPV blood pressure models. Simulation studies are provided to validate the online model estimation and the LPV blood pressure control using phenylephrine drug injection models representing patients showing sensitive, nominal and insensitive response to the drug.

  9. PREDICTIVE ACCURACY OF TRANSCEREBELLAR DIAMETER IN COMPARISON WITH OTHER FOETAL BIOMETRIC PARAMETERS FOR GESTATIONAL AGE ESTIMATION AMONG PREGNANT NIGERIAN WOMEN.

    PubMed

    Adeyekun, A A; Orji, M O

    2014-04-01

    To compare the predictive accuracy of foetal trans-cerebellar diameter (TCD) with those of other biometric parameters in the estimation of gestational age (GA). A cross-sectional study. The University of Benin Teaching Hospital, Nigeria. Four hundred and fifty healthy singleton pregnant women, between 14-42 weeks gestation. Trans-cerebellar diameter (TCD), biparietal diameter (BPD), femur length (FL), abdominal circumference (AC) values across the gestational age range studied. Correlation and predictive values of TCD compared to those of other biometric parameters. The range of values for TCD was 11.9 - 59.7mm (mean = 34.2 ± 14.1mm). TCD correlated more significantly with menstrual age compared with other biometric parameters (r = 0.984, p = 0.000). TCD had a higher predictive accuracy of 96.9% ± 12 days), BPD (93.8% ± 14.1 days). AC (92.7% ± 15.3 days). TCD has a stronger predictive accuracy for gestational age compared to other routinely used foetal biometric parameters among Nigerian Africans.

  10. The contribution of NOAA/CMDL ground-based measurements to understanding long-term stratospheric changes

    NASA Astrophysics Data System (ADS)

    Montzka, S. A.; Butler, J. H.; Dutton, G.; Thompson, T. M.; Hall, B.; Mondeel, D. J.; Elkins, J. W.

    2005-05-01

    The El-Nino/Southern-Oscillation (ENSO) dominates interannual climate variability and plays, therefore, a key role in seasonal-to-interannual prediction. Much is known by now about the main physical mechanisms that give rise to and modulate ENSO, but the values of several parameters that enter these mechanisms are an important unknown. We apply Extended Kalman Filtering (EKF) for both model state and parameter estimation in an intermediate, nonlinear, coupled ocean--atmosphere model of ENSO. The coupled model consists of an upper-ocean, reduced-gravity model of the Tropical Pacific and a steady-state atmospheric response to the sea surface temperature (SST). The model errors are assumed to be mainly in the atmospheric wind stress, and assimilated data are equatorial Pacific SSTs. Model behavior is very sensitive to two key parameters: (i) μ, the ocean-atmosphere coupling coefficient between SST and wind stress anomalies; and (ii) δs, the surface-layer coefficient. Previous work has shown that δs determines the period of the model's self-sustained oscillation, while μ measures the degree of nonlinearity. Depending on the values of these parameters, the spatio-temporal pattern of model solutions is either that of a delayed oscillator or of a westward propagating mode. Estimation of these parameters is tested first on synthetic data and allows us to recover the delayed-oscillator mode starting from model parameter values that correspond to the westward-propagating case. Assimilation of SST data from the NCEP-NCAR Reanalysis-2 shows that the parameters can vary on fairly short time scales and switch between values that approximate the two distinct modes of ENSO behavior. Rapid adjustments of these parameters occur, in particular, during strong ENSO events. Ways to apply EKF parameter estimation efficiently to state-of-the-art coupled ocean--atmosphere GCMs will be discussed.

  11. Accounting for uncertainty in model-based prevalence estimation: paratuberculosis control in dairy herds.

    PubMed

    Davidson, Ross S; McKendrick, Iain J; Wood, Joanna C; Marion, Glenn; Greig, Alistair; Stevenson, Karen; Sharp, Michael; Hutchings, Michael R

    2012-09-10

    A common approach to the application of epidemiological models is to determine a single (point estimate) parameterisation using the information available in the literature. However, in many cases there is considerable uncertainty about parameter values, reflecting both the incomplete nature of current knowledge and natural variation, for example between farms. Furthermore model outcomes may be highly sensitive to different parameter values. Paratuberculosis is an infection for which many of the key parameter values are poorly understood and highly variable, and for such infections there is a need to develop and apply statistical techniques which make maximal use of available data. A technique based on Latin hypercube sampling combined with a novel reweighting method was developed which enables parameter uncertainty and variability to be incorporated into a model-based framework for estimation of prevalence. The method was evaluated by applying it to a simulation of paratuberculosis in dairy herds which combines a continuous time stochastic algorithm with model features such as within herd variability in disease development and shedding, which have not been previously explored in paratuberculosis models. Generated sample parameter combinations were assigned a weight, determined by quantifying the model's resultant ability to reproduce prevalence data. Once these weights are generated the model can be used to evaluate other scenarios such as control options. To illustrate the utility of this approach these reweighted model outputs were used to compare standard test and cull control strategies both individually and in combination with simple husbandry practices that aim to reduce infection rates. The technique developed has been shown to be applicable to a complex model incorporating realistic control options. For models where parameters are not well known or subject to significant variability, the reweighting scheme allowed estimated distributions of parameter values to be combined with additional sources of information, such as that available from prevalence distributions, resulting in outputs which implicitly handle variation and uncertainty. This methodology allows for more robust predictions from modelling approaches by allowing for parameter uncertainty and combining different sources of information, and is thus expected to be useful in application to a large number of disease systems.

  12. Bias in error estimation when using cross-validation for model selection.

    PubMed

    Varma, Sudhir; Simon, Richard

    2006-02-23

    Cross-validation (CV) is an effective method for estimating the prediction error of a classifier. Some recent articles have proposed methods for optimizing classifiers by choosing classifier parameter values that minimize the CV error estimate. We have evaluated the validity of using the CV error estimate of the optimized classifier as an estimate of the true error expected on independent data. We used CV to optimize the classification parameters for two kinds of classifiers; Shrunken Centroids and Support Vector Machines (SVM). Random training datasets were created, with no difference in the distribution of the features between the two classes. Using these "null" datasets, we selected classifier parameter values that minimized the CV error estimate. 10-fold CV was used for Shrunken Centroids while Leave-One-Out-CV (LOOCV) was used for the SVM. Independent test data was created to estimate the true error. With "null" and "non null" (with differential expression between the classes) data, we also tested a nested CV procedure, where an inner CV loop is used to perform the tuning of the parameters while an outer CV is used to compute an estimate of the error. The CV error estimate for the classifier with the optimal parameters was found to be a substantially biased estimate of the true error that the classifier would incur on independent data. Even though there is no real difference between the two classes for the "null" datasets, the CV error estimate for the Shrunken Centroid with the optimal parameters was less than 30% on 18.5% of simulated training data-sets. For SVM with optimal parameters the estimated error rate was less than 30% on 38% of "null" data-sets. Performance of the optimized classifiers on the independent test set was no better than chance. The nested CV procedure reduces the bias considerably and gives an estimate of the error that is very close to that obtained on the independent testing set for both Shrunken Centroids and SVM classifiers for "null" and "non-null" data distributions. We show that using CV to compute an error estimate for a classifier that has itself been tuned using CV gives a significantly biased estimate of the true error. Proper use of CV for estimating true error of a classifier developed using a well defined algorithm requires that all steps of the algorithm, including classifier parameter tuning, be repeated in each CV loop. A nested CV procedure provides an almost unbiased estimate of the true error.

  13. Estimation of Geodetic and Geodynamical Parameters with VieVS

    NASA Technical Reports Server (NTRS)

    Spicakova, Hana; Bohm, Johannes; Bohm, Sigrid; Nilsson, tobias; Pany, Andrea; Plank, Lucia; Teke, Kamil; Schuh, Harald

    2010-01-01

    Since 2008 the VLBI group at the Institute of Geodesy and Geophysics at TU Vienna has focused on the development of a new VLBI data analysis software called VieVS (Vienna VLBI Software). One part of the program, currently under development, is a unit for parameter estimation in so-called global solutions, where the connection of the single sessions is done by stacking at the normal equation level. We can determine time independent geodynamical parameters such as Love and Shida numbers of the solid Earth tides. Apart from the estimation of the constant nominal values of Love and Shida numbers for the second degree of the tidal potential, it is possible to determine frequency dependent values in the diurnal band together with the resonance frequency of Free Core Nutation. In this paper we show first results obtained from the 24-hour IVS R1 and R4 sessions.

  14. Regression dilution in the proportional hazards model.

    PubMed

    Hughes, M D

    1993-12-01

    The problem of regression dilution arising from covariate measurement error is investigated for survival data using the proportional hazards model. The naive approach to parameter estimation is considered whereby observed covariate values are used, inappropriately, in the usual analysis instead of the underlying covariate values. A relationship between the estimated parameter in large samples and the true parameter is obtained showing that the bias does not depend on the form of the baseline hazard function when the errors are normally distributed. With high censorship, adjustment of the naive estimate by the factor 1 + lambda, where lambda is the ratio of within-person variability about an underlying mean level to the variability of these levels in the population sampled, removes the bias. As censorship increases, the adjustment required increases and when there is no censorship is markedly higher than 1 + lambda and depends also on the true risk relationship.

  15. A Systematic Approach for Model-Based Aircraft Engine Performance Estimation

    NASA Technical Reports Server (NTRS)

    Simon, Donald L.; Garg, Sanjay

    2010-01-01

    A requirement for effective aircraft engine performance estimation is the ability to account for engine degradation, generally described in terms of unmeasurable health parameters such as efficiencies and flow capacities related to each major engine module. This paper presents a linear point design methodology for minimizing the degradation-induced error in model-based aircraft engine performance estimation applications. The technique specifically focuses on the underdetermined estimation problem, where there are more unknown health parameters than available sensor measurements. A condition for Kalman filter-based estimation is that the number of health parameters estimated cannot exceed the number of sensed measurements. In this paper, the estimated health parameter vector will be replaced by a reduced order tuner vector whose dimension is equivalent to the sensed measurement vector. The reduced order tuner vector is systematically selected to minimize the theoretical mean squared estimation error of a maximum a posteriori estimator formulation. This paper derives theoretical estimation errors at steady-state operating conditions, and presents the tuner selection routine applied to minimize these values. Results from the application of the technique to an aircraft engine simulation are presented and compared to the estimation accuracy achieved through conventional maximum a posteriori and Kalman filter estimation approaches. Maximum a posteriori estimation results demonstrate that reduced order tuning parameter vectors can be found that approximate the accuracy of estimating all health parameters directly. Kalman filter estimation results based on the same reduced order tuning parameter vectors demonstrate that significantly improved estimation accuracy can be achieved over the conventional approach of selecting a subset of health parameters to serve as the tuner vector. However, additional development is necessary to fully extend the methodology to Kalman filter-based estimation applications.

  16. Calibration of sea ice dynamic parameters in an ocean-sea ice model using an ensemble Kalman filter

    NASA Astrophysics Data System (ADS)

    Massonnet, F.; Goosse, H.; Fichefet, T.; Counillon, F.

    2014-07-01

    The choice of parameter values is crucial in the course of sea ice model development, since parameters largely affect the modeled mean sea ice state. Manual tuning of parameters will soon become impractical, as sea ice models will likely include more parameters to calibrate, leading to an exponential increase of the number of possible combinations to test. Objective and automatic methods for parameter calibration are thus progressively called on to replace the traditional heuristic, "trial-and-error" recipes. Here a method for calibration of parameters based on the ensemble Kalman filter is implemented, tested and validated in the ocean-sea ice model NEMO-LIM3. Three dynamic parameters are calibrated: the ice strength parameter P*, the ocean-sea ice drag parameter Cw, and the atmosphere-sea ice drag parameter Ca. In twin, perfect-model experiments, the default parameter values are retrieved within 1 year of simulation. Using 2007-2012 real sea ice drift data, the calibration of the ice strength parameter P* and the oceanic drag parameter Cw improves clearly the Arctic sea ice drift properties. It is found that the estimation of the atmospheric drag Ca is not necessary if P* and Cw are already estimated. The large reduction in the sea ice speed bias with calibrated parameters comes with a slight overestimation of the winter sea ice areal export through Fram Strait and a slight improvement in the sea ice thickness distribution. Overall, the estimation of parameters with the ensemble Kalman filter represents an encouraging alternative to manual tuning for ocean-sea ice models.

  17. Estimation of hydraulic parameters from an unconfined aquifer test conducted in a glacial outwash deposit, Cape Cod, Massachusetts

    USGS Publications Warehouse

    Moench, A.F.; Garabedian, Stephen P.; LeBlanc, Denis R.

    2000-01-01

    An aquifer test conducted in a sand and gravel, glacial outwash deposit on Cape Cod, Massachusetts was analyzed by means of a model for flow to a partially penetrating well in a homogeneous, anisotropic unconfined aquifer. The model is designed to account for all significant mechanisms expected to influence drawdown in observation piezometers and in the pumped well. In addition to the usual fluid-flow and storage processes, additional processes include effects of storage in the pumped well, storage in observation piezometers, effects of skin at the pumped-well screen, and effects of drainage from the zone above the water table. The aquifer was pumped at a rate of 320 gallons per minute for 72-hours and drawdown measurements were made in the pumped well and in 20 piezometers located at various distances from the pumped well and depths below the land surface. To facilitate the analysis, an automatic parameter estimation algorithm was used to obtain relevant unconfined aquifer parameters, including the saturated thickness and a set of empirical parameters that relate to gradual drainage from the unsaturated zone. Drainage from the unsaturated zone is treated in this paper as a finite series of exponential terms, each of which contains one empirical parameter that is to be determined. It was necessary to account for effects of gradual drainage from the unsaturated zone to obtain satisfactory agreement between measured and simulated drawdown, particularly in piezometers located near the water table. The commonly used assumption of instantaneous drainage from the unsaturated zone gives rise to large discrepancies between measured and predicted drawdown in the intermediate-time range and can result in inaccurate estimates of aquifer parameters when automatic parameter estimation procedures are used. The values of the estimated hydraulic parameters are consistent with estimates from prior studies and from what is known about the aquifer at the site. Effects of heterogeneity at the site were small as measured drawdowns in all piezometers and wells were very close to the simulated values for a homogeneous porous medium. The estimated values are: specific yield, 0.26; saturated thickness, 170 feet; horizontal hydraulic conductivity, 0.23 feet per minute; vertical hydraulic conductivity, 0.14 feet per minute; and specific storage, 1.3x10-5 per foot. It was found that drawdown in only a few piezometers strategically located at depth near the pumped well yielded parameter estimates close to the estimates obtained for the entire data set analyzed simultaneously. If the influence of gradual drainage from the unsaturated zone is not taken into account, specific yield is significantly underestimated even in these deep-seated piezometers. This helps to explain the low values of specific yield often reported for granular aquifers in the literature. If either the entire data set or only the drawdown in selected deep-seated piezometers was used, it was found unnecessary to conduct the test for the full 72-hours to obtain accurate estimates of the hydraulic parameters. For some piezometer groups, practically identical results would be obtained for an aquifer test conducted for only 8-hours. Drawdowns measured in the pumped well and piezometers at distant locations were diagnostic only of aquifer transmissivity.

  18. A Monte Carlo Evaluation of Estimated Parameters of Five Shrinkage Estimate Formuli.

    ERIC Educational Resources Information Center

    Newman, Isadore; And Others

    A Monte Carlo study was conducted to estimate the efficiency of and the relationship between five equations and the use of cross validation as methods for estimating shrinkage in multiple correlations. Two of the methods were intended to estimate shrinkage to population values and the other methods were intended to estimate shrinkage from sample…

  19. Exploration of DGVM Parameter Solution Space Using Simulated Annealing: Implications for Forecast Uncertainties

    NASA Astrophysics Data System (ADS)

    Wells, J. R.; Kim, J. B.

    2011-12-01

    Parameters in dynamic global vegetation models (DGVMs) are thought to be weakly constrained and can be a significant source of errors and uncertainties. DGVMs use between 5 and 26 plant functional types (PFTs) to represent the average plant life form in each simulated plot, and each PFT typically has a dozen or more parameters that define the way it uses resource and responds to the simulated growing environment. Sensitivity analysis explores how varying parameters affects the output, but does not do a full exploration of the parameter solution space. The solution space for DGVM parameter values are thought to be complex and non-linear; and multiple sets of acceptable parameters may exist. In published studies, PFT parameters are estimated from published literature, and often a parameter value is estimated from a single published value. Further, the parameters are "tuned" using somewhat arbitrary, "trial-and-error" methods. BIOMAP is a new DGVM created by fusing MAPSS biogeography model with Biome-BGC. It represents the vegetation of North America using 26 PFTs. We are using simulated annealing, a global search method, to systematically and objectively explore the solution space for the BIOMAP PFTs and system parameters important for plant water use. We defined the boundaries of the solution space by obtaining maximum and minimum values from published literature, and where those were not available, using +/-20% of current values. We used stratified random sampling to select a set of grid cells representing the vegetation of the conterminous USA. Simulated annealing algorithm is applied to the parameters for spin-up and a transient run during the historical period 1961-1990. A set of parameter values is considered acceptable if the associated simulation run produces a modern potential vegetation distribution map that is as accurate as one produced by trial-and-error calibration. We expect to confirm that the solution space is non-linear and complex, and that multiple acceptable parameter sets exist. Further we expect to demonstrate that the multiple parameter sets produce significantly divergent future forecasts in NEP, C storage, and ET and runoff; and thereby identify a highly important source of DGVM uncertainty

  20. Impact of biology knowledge on the conservation and management of large pelagic sharks.

    PubMed

    Yokoi, Hiroki; Ijima, Hirotaka; Ohshimo, Seiji; Yokawa, Kotaro

    2017-09-06

    Population growth rate, which depends on several biological parameters, is valuable information for the conservation and management of pelagic sharks, such as blue and shortfin mako sharks. However, reported biological parameters for estimating the population growth rates of these sharks differ by sex and display large variability. To estimate the appropriate population growth rate and clarify relationships between growth rate and relevant biological parameters, we developed a two-sex age-structured matrix population model and estimated the population growth rate using combinations of biological parameters. We addressed elasticity analysis and clarified the population growth rate sensitivity. For the blue shark, the estimated median population growth rate was 0.384 with a range of minimum and maximum values of 0.195-0.533, whereas those values of the shortfin mako shark were 0.102 and 0.007-0.318, respectively. The maturity age of male sharks had the largest impact for blue sharks, whereas that of female sharks had the largest impact for shortfin mako sharks. Hypotheses for the survival process of sharks also had a large impact on the population growth rate estimation. Both shark maturity age and survival rate were based on ageing validation data, indicating the importance of validating the quality of these data for the conservation and management of large pelagic sharks.

  1. Assessing the reliability of dose coefficients for exposure to radioiodine by members of the public, accounting for dosimetric and risk model uncertainties.

    PubMed

    Puncher, M; Zhang, W; Harrison, J D; Wakeford, R

    2017-06-26

    Assessments of risk to a specific population group resulting from internal exposure to a particular radionuclide can be used to assess the reliability of the appropriate International Commission on Radiological Protection (ICRP) dose coefficients used as a radiation protection device for the specified exposure pathway. An estimate of the uncertainty on the associated risk is important for informing judgments on reliability; a derived uncertainty factor, UF, is an estimate of the 95% probable geometric difference between the best risk estimate and the nominal risk and is a useful tool for making this assessment. This paper describes the application of parameter uncertainty analysis to quantify uncertainties resulting from internal exposures to radioiodine by members of the public, specifically 1, 10 and 20-year old females from the population of England and Wales. Best estimates of thyroid cancer incidence risk (lifetime attributable risk) are calculated for ingestion or inhalation of 129 I and 131 I, accounting for uncertainties in biokinetic model and cancer risk model parameter values. These estimates are compared with the equivalent ICRP derived nominal age-, sex- and population-averaged estimates of excess thyroid cancer incidence to obtain UFs. Derived UF values for ingestion or inhalation of 131 I for 1 year, 10-year and 20-year olds are around 28, 12 and 6, respectively, when compared with ICRP Publication 103 nominal values, and 9, 7 and 14, respectively, when compared with ICRP Publication 60 values. Broadly similar results were obtained for 129 I. The uncertainties on risk estimates are largely determined by uncertainties on risk model parameters rather than uncertainties on biokinetic model parameters. An examination of the sensitivity of the results to the risk models and populations used in the calculations show variations in the central estimates of risk of a factor of around 2-3. It is assumed that the direct proportionality of excess thyroid cancer risk and dose observed at low to moderate acute doses and incorporated in the risk models also applies to very small doses received at very low dose rates; the uncertainty in this assumption is considerable, but largely unquantifiable. The UF values illustrate the need for an informed approach to the use of ICRP dose and risk coefficients.

  2. Calibration Software for Use with Jurassicprok

    NASA Technical Reports Server (NTRS)

    Chapin, Elaine; Hensley, Scott; Siqueira, Paul

    2004-01-01

    The Jurassicprok Interferometric Calibration Software (also called "Calibration Processor" or simply "CP") estimates the calibration parameters of an airborne synthetic-aperture-radar (SAR) system, the raw measurement data of which are processed by the Jurassicprok software described in the preceding article. Calibration parameters estimated by CP include time delays, baseline offsets, phase screens, and radiometric offsets. CP examines raw radar-pulse data, single-look complex image data, and digital elevation map data. For each type of data, CP compares the actual values with values expected on the basis of ground-truth data. CP then converts the differences between the actual and expected values into updates for the calibration parameters in an interferometric calibration file (ICF) and a radiometric calibration file (RCF) for the particular SAR system. The updated ICF and RCF are used as inputs to both Jurassicprok and to the companion Motion Measurement Processor software (described in the following article) for use in generating calibrated digital elevation maps.

  3. Bayesian approach to estimate AUC, partition coefficient and drug targeting index for studies with serial sacrifice design.

    PubMed

    Wang, Tianli; Baron, Kyle; Zhong, Wei; Brundage, Richard; Elmquist, William

    2014-03-01

    The current study presents a Bayesian approach to non-compartmental analysis (NCA), which provides the accurate and precise estimate of AUC 0 (∞) and any AUC 0 (∞) -based NCA parameter or derivation. In order to assess the performance of the proposed method, 1,000 simulated datasets were generated in different scenarios. A Bayesian method was used to estimate the tissue and plasma AUC 0 (∞) s and the tissue-to-plasma AUC 0 (∞) ratio. The posterior medians and the coverage of 95% credible intervals for the true parameter values were examined. The method was applied to laboratory data from a mice brain distribution study with serial sacrifice design for illustration. Bayesian NCA approach is accurate and precise in point estimation of the AUC 0 (∞) and the partition coefficient under a serial sacrifice design. It also provides a consistently good variance estimate, even considering the variability of the data and the physiological structure of the pharmacokinetic model. The application in the case study obtained a physiologically reasonable posterior distribution of AUC, with a posterior median close to the value estimated by classic Bailer-type methods. This Bayesian NCA approach for sparse data analysis provides statistical inference on the variability of AUC 0 (∞) -based parameters such as partition coefficient and drug targeting index, so that the comparison of these parameters following destructive sampling becomes statistically feasible.

  4. Regression without truth with Markov chain Monte-Carlo

    NASA Astrophysics Data System (ADS)

    Madan, Hennadii; Pernuš, Franjo; Likar, Boštjan; Å piclin, Žiga

    2017-03-01

    Regression without truth (RWT) is a statistical technique for estimating error model parameters of each method in a group of methods used for measurement of a certain quantity. A very attractive aspect of RWT is that it does not rely on a reference method or "gold standard" data, which is otherwise difficult RWT was used for a reference-free performance comparison of several methods for measuring left ventricular ejection fraction (EF), i.e. a percentage of blood leaving the ventricle each time the heart contracts, and has since been applied for various other quantitative imaging biomarkerss (QIBs). Herein, we show how Markov chain Monte-Carlo (MCMC), a computational technique for drawing samples from a statistical distribution with probability density function known only up to a normalizing coefficient, can be used to augment RWT to gain a number of important benefits compared to the original approach based on iterative optimization. For instance, the proposed MCMC-based RWT enables the estimation of joint posterior distribution of the parameters of the error model, straightforward quantification of uncertainty of the estimates, estimation of true value of the measurand and corresponding credible intervals (CIs), does not require a finite support for prior distribution of the measureand generally has a much improved robustness against convergence to non-global maxima. The proposed approach is validated using synthetic data that emulate the EF data for 45 patients measured with 8 different methods. The obtained results show that 90% CI of the corresponding parameter estimates contain the true values of all error model parameters and the measurand. A potential real-world application is to take measurements of a certain QIB several different methods and then use the proposed framework to compute the estimates of the true values and their uncertainty, a vital information for diagnosis based on QIB.

  5. Approximation of the breast height diameter distribution of two-cohort stands by mixture models I Parameter estimation

    Treesearch

    Rafal Podlaski; Francis A. Roesch

    2013-01-01

    Study assessed the usefulness of various methods for choosing the initial values for the numerical procedures for estimating the parameters of mixture distributions and analysed variety of mixture models to approximate empirical diameter at breast height (dbh) distributions. Two-component mixtures of either the Weibull distribution or the gamma distribution were...

  6. Weighted regression analysis and interval estimators

    Treesearch

    Donald W. Seegrist

    1974-01-01

    A method for deriving the weighted least squares estimators for the parameters of a multiple regression model. Confidence intervals for expected values, and prediction intervals for the means of future samples are given.

  7. Probability Distribution Estimated From the Minimum, Maximum, and Most Likely Values: Applied to Turbine Inlet Temperature Uncertainty

    NASA Technical Reports Server (NTRS)

    Holland, Frederic A., Jr.

    2004-01-01

    Modern engineering design practices are tending more toward the treatment of design parameters as random variables as opposed to fixed, or deterministic, values. The probabilistic design approach attempts to account for the uncertainty in design parameters by representing them as a distribution of values rather than as a single value. The motivations for this effort include preventing excessive overdesign as well as assessing and assuring reliability, both of which are important for aerospace applications. However, the determination of the probability distribution is a fundamental problem in reliability analysis. A random variable is often defined by the parameters of the theoretical distribution function that gives the best fit to experimental data. In many cases the distribution must be assumed from very limited information or data. Often the types of information that are available or reasonably estimated are the minimum, maximum, and most likely values of the design parameter. For these situations the beta distribution model is very convenient because the parameters that define the distribution can be easily determined from these three pieces of information. Widely used in the field of operations research, the beta model is very flexible and is also useful for estimating the mean and standard deviation of a random variable given only the aforementioned three values. However, an assumption is required to determine the four parameters of the beta distribution from only these three pieces of information (some of the more common distributions, like the normal, lognormal, gamma, and Weibull distributions, have two or three parameters). The conventional method assumes that the standard deviation is a certain fraction of the range. The beta parameters are then determined by solving a set of equations simultaneously. A new method developed in-house at the NASA Glenn Research Center assumes a value for one of the beta shape parameters based on an analogy with the normal distribution (ref.1). This new approach allows for a very simple and direct algebraic solution without restricting the standard deviation. The beta parameters obtained by the new method are comparable to the conventional method (and identical when the distribution is symmetrical). However, the proposed method generally produces a less peaked distribution with a slightly larger standard deviation (up to 7 percent) than the conventional method in cases where the distribution is asymmetric or skewed. The beta distribution model has now been implemented into the Fast Probability Integration (FPI) module used in the NESSUS computer code for probabilistic analyses of structures (ref. 2).

  8. Estimation of the sea surface's two-scale backscatter parameters

    NASA Technical Reports Server (NTRS)

    Wentz, F. J.

    1978-01-01

    The relationship between the sea-surface normalized radar cross section and the friction velocity vector is determined using a parametric two-scale scattering model. The model parameters are found from a nonlinear maximum likelihood estimation. The estimation is based on aircraft scatterometer measurements and the sea-surface anemometer measurements collected during the JONSWAP '75 experiment. The estimates of the ten model parameters converge to realistic values that are in good agreement with the available oceanographic data. The rms discrepancy between the model and the cross section measurements is 0.7 db, which is the rms sum of a 0.3 db average measurement error and a 0.6 db modeling error.

  9. Achieving metrological precision limits through postselection

    NASA Astrophysics Data System (ADS)

    Alves, G. Bié; Pimentel, A.; Hor-Meyll, M.; Walborn, S. P.; Davidovich, L.; Filho, R. L. de Matos

    2017-01-01

    Postselection strategies have been proposed with the aim of amplifying weak signals, which may help to overcome detection thresholds associated with technical noise in high-precision measurements. Here we use an optical setup to experimentally explore two different postselection protocols for the estimation of a small parameter: a weak-value amplification procedure and an alternative method that does not provide amplification but nonetheless is shown to be more robust for the sake of parameter estimation. Each technique leads approximately to the saturation of quantum limits for the estimation precision, expressed by the Cramér-Rao bound. For both situations, we show that parameter estimation is improved when the postselection statistics are considered together with the measurement device.

  10. Single-Step BLUP with Varying Genotyping Effort in Open-Pollinated Picea glauca.

    PubMed

    Ratcliffe, Blaise; El-Dien, Omnia Gamal; Cappa, Eduardo P; Porth, Ilga; Klápště, Jaroslav; Chen, Charles; El-Kassaby, Yousry A

    2017-03-10

    Maximization of genetic gain in forest tree breeding programs is contingent on the accuracy of the predicted breeding values and precision of the estimated genetic parameters. We investigated the effect of the combined use of contemporary pedigree information and genomic relatedness estimates on the accuracy of predicted breeding values and precision of estimated genetic parameters, as well as rankings of selection candidates, using single-step genomic evaluation (HBLUP). In this study, two traits with diverse heritabilities [tree height (HT) and wood density (WD)] were assessed at various levels of family genotyping efforts (0, 25, 50, 75, and 100%) from a population of white spruce ( Picea glauca ) consisting of 1694 trees from 214 open-pollinated families, representing 43 provenances in Québec, Canada. The results revealed that HBLUP bivariate analysis is effective in reducing the known bias in heritability estimates of open-pollinated populations, as it exposes hidden relatedness, potential pedigree errors, and inbreeding. The addition of genomic information in the analysis considerably improved the accuracy in breeding value estimates by accounting for both Mendelian sampling and historical coancestry that were not captured by the contemporary pedigree alone. Increasing family genotyping efforts were associated with continuous improvement in model fit, precision of genetic parameters, and breeding value accuracy. Yet, improvements were observed even at minimal genotyping effort, indicating that even modest genotyping effort is effective in improving genetic evaluation. The combined utilization of both pedigree and genomic information may be a cost-effective approach to increase the accuracy of breeding values in forest tree breeding programs where shallow pedigrees and large testing populations are the norm. Copyright © 2017 Ratcliffe et al.

  11. Estimating parameter of Rayleigh distribution by using Maximum Likelihood method and Bayes method

    NASA Astrophysics Data System (ADS)

    Ardianti, Fitri; Sutarman

    2018-01-01

    In this paper, we use Maximum Likelihood estimation and Bayes method under some risk function to estimate parameter of Rayleigh distribution to know the best method. The prior knowledge which used in Bayes method is Jeffrey’s non-informative prior. Maximum likelihood estimation and Bayes method under precautionary loss function, entropy loss function, loss function-L 1 will be compared. We compare these methods by bias and MSE value using R program. After that, the result will be displayed in tables to facilitate the comparisons.

  12. Orbit Estimation of Non-Cooperative Maneuvering Spacecraft

    DTIC Science & Technology

    2015-06-01

    only take on values that generate real sigma points; therefore, λ > −n. The additional weighting scheme is outlined in the following equations κ = α2...orbit shapes resulted in a similar model weighting. Additional cases of this orbit type also resulted in heavily weighting smaller η value models. It is...determined using both the symmetric and additional parameters UTs. The best values for the weighting parameters are then compared for each test case

  13. Thermodynamically consistent model calibration in chemical kinetics

    PubMed Central

    2011-01-01

    Background The dynamics of biochemical reaction systems are constrained by the fundamental laws of thermodynamics, which impose well-defined relationships among the reaction rate constants characterizing these systems. Constructing biochemical reaction systems from experimental observations often leads to parameter values that do not satisfy the necessary thermodynamic constraints. This can result in models that are not physically realizable and may lead to inaccurate, or even erroneous, descriptions of cellular function. Results We introduce a thermodynamically consistent model calibration (TCMC) method that can be effectively used to provide thermodynamically feasible values for the parameters of an open biochemical reaction system. The proposed method formulates the model calibration problem as a constrained optimization problem that takes thermodynamic constraints (and, if desired, additional non-thermodynamic constraints) into account. By calculating thermodynamically feasible values for the kinetic parameters of a well-known model of the EGF/ERK signaling cascade, we demonstrate the qualitative and quantitative significance of imposing thermodynamic constraints on these parameters and the effectiveness of our method for accomplishing this important task. MATLAB software, using the Systems Biology Toolbox 2.1, can be accessed from http://www.cis.jhu.edu/~goutsias/CSS lab/software.html. An SBML file containing the thermodynamically feasible EGF/ERK signaling cascade model can be found in the BioModels database. Conclusions TCMC is a simple and flexible method for obtaining physically plausible values for the kinetic parameters of open biochemical reaction systems. It can be effectively used to recalculate a thermodynamically consistent set of parameter values for existing thermodynamically infeasible biochemical reaction models of cellular function as well as to estimate thermodynamically feasible values for the parameters of new models. Furthermore, TCMC can provide dimensionality reduction, better estimation performance, and lower computational complexity, and can help to alleviate the problem of data overfitting. PMID:21548948

  14. A Bayesian approach to tracking patients having changing pharmacokinetic parameters

    NASA Technical Reports Server (NTRS)

    Bayard, David S.; Jelliffe, Roger W.

    2004-01-01

    This paper considers the updating of Bayesian posterior densities for pharmacokinetic models associated with patients having changing parameter values. For estimation purposes it is proposed to use the Interacting Multiple Model (IMM) estimation algorithm, which is currently a popular algorithm in the aerospace community for tracking maneuvering targets. The IMM algorithm is described, and compared to the multiple model (MM) and Maximum A-Posteriori (MAP) Bayesian estimation methods, which are presently used for posterior updating when pharmacokinetic parameters do not change. Both the MM and MAP Bayesian estimation methods are used in their sequential forms, to facilitate tracking of changing parameters. Results indicate that the IMM algorithm is well suited for tracking time-varying pharmacokinetic parameters in acutely ill and unstable patients, incurring only about half of the integrated error compared to the sequential MM and MAP methods on the same example.

  15. Dynamic Modeling of Cell-Free Biochemical Networks Using Effective Kinetic Models

    DTIC Science & Technology

    2015-03-16

    sensitivity value was the maximum uncertainty in that value estimated by the Sobol method. 2.4. Global Sensitivity Analysis of the Reduced Order Coagulation...sensitivity analysis, using the variance-based method of Sobol , to estimate which parameters controlled the performance of the reduced order model [69]. We...Environment. Comput. Sci. Eng. 2007, 9, 90–95. 69. Sobol , I. Global sensitivity indices for nonlinear mathematical models and their Monte Carlo estimates

  16. A computer program (MODFLOWP) for estimating parameters of a transient, three-dimensional ground-water flow model using nonlinear regression

    USGS Publications Warehouse

    Hill, Mary Catherine

    1992-01-01

    This report documents a new version of the U.S. Geological Survey modular, three-dimensional, finite-difference, ground-water flow model (MODFLOW) which, with the new Parameter-Estimation Package that also is documented in this report, can be used to estimate parameters by nonlinear regression. The new version of MODFLOW is called MODFLOWP (pronounced MOD-FLOW*P), and functions nearly identically to MODFLOW when the ParameterEstimation Package is not used. Parameters are estimated by minimizing a weighted least-squares objective function by the modified Gauss-Newton method or by a conjugate-direction method. Parameters used to calculate the following MODFLOW model inputs can be estimated: Transmissivity and storage coefficient of confined layers; hydraulic conductivity and specific yield of unconfined layers; vertical leakance; vertical anisotropy (used to calculate vertical leakance); horizontal anisotropy; hydraulic conductance of the River, Streamflow-Routing, General-Head Boundary, and Drain Packages; areal recharge rates; maximum evapotranspiration; pumpage rates; and the hydraulic head at constant-head boundaries. Any spatial variation in parameters can be defined by the user. Data used to estimate parameters can include existing independent estimates of parameter values, observed hydraulic heads or temporal changes in hydraulic heads, and observed gains and losses along head-dependent boundaries (such as streams). Model output includes statistics for analyzing the parameter estimates and the model; these statistics can be used to quantify the reliability of the resulting model, to suggest changes in model construction, and to compare results of models constructed in different ways.

  17. Measurement of unsaturated hydraulic properties and evaluation of property-transfer models for deep sedimentary interbeds, Idaho National Laboratory, Idaho

    USGS Publications Warehouse

    Perkins, Kimberlie; Johnson, Brittany D.; Mirus, Benjamin B.

    2014-01-01

    During 2013–14, the USGS, in cooperation with the U.S. Department of Energy, focused on further characterization of the sedimentary interbeds below the future site of the proposed Remote Handled Low-Level Waste (RHLLW) facility, which is intended for the long-term storage of low-level radioactive waste. Twelve core samples from the sedimentary interbeds from a borehole near the proposed facility were collected for laboratory analysis of hydraulic properties, which also allowed further testing of the property-transfer modeling approach. For each core sample, the steady-state centrifuge method was used to measure relations between matric potential, saturation, and conductivity. These laboratory measurements were compared to water-retention and unsaturated hydraulic conductivity parameters estimated using the established property-transfer models. For each core sample obtained, the agreement between measured and estimated hydraulic parameters was evaluated quantitatively using the Pearson correlation coefficient (r). The highest correlation is for saturated hydraulic conductivity (Ksat) with an r value of 0.922. The saturated water content (qsat) also exhibits a strong linear correlation with an r value of 0.892. The curve shape parameter (λ) has a value of 0.731, whereas the curve scaling parameter (yo) has the lowest r value of 0.528. The r values demonstrate that model predictions correspond well to the laboratory measured properties for most parameters, which supports the value of extending this approach for quantifying unsaturated hydraulic properties at various sites throughout INL.

  18. Bifurcation and Stability Analysis of the Equilibrium States in Thermodynamic Systems in a Small Vicinity of the Equilibrium Values of Parameters

    NASA Astrophysics Data System (ADS)

    Barsuk, Alexandr A.; Paladi, Florentin

    2018-04-01

    The dynamic behavior of thermodynamic system, described by one order parameter and one control parameter, in a small neighborhood of ordinary and bifurcation equilibrium values of the system parameters is studied. Using the general methods of investigating the branching (bifurcations) of solutions for nonlinear equations, we performed an exhaustive analysis of the order parameter dependences on the control parameter in a small vicinity of the equilibrium values of parameters, including the stability analysis of the equilibrium states, and the asymptotic behavior of the order parameter dependences on the control parameter (bifurcation diagrams). The peculiarities of the transition to an unstable state of the system are discussed, and the estimates of the transition time to the unstable state in the neighborhood of ordinary and bifurcation equilibrium values of parameters are given. The influence of an external field on the dynamic behavior of thermodynamic system is analyzed, and the peculiarities of the system dynamic behavior are discussed near the ordinary and bifurcation equilibrium values of parameters in the presence of external field. The dynamic process of magnetization of a ferromagnet is discussed by using the general methods of bifurcation and stability analysis presented in the paper.

  19. Fisher information theory for parameter estimation in single molecule microscopy: tutorial

    PubMed Central

    Chao, Jerry; Ward, E. Sally; Ober, Raimund J.

    2016-01-01

    Estimation of a parameter of interest from image data represents a task that is commonly carried out in single molecule microscopy data analysis. The determination of the positional coordinates of a molecule from its image, for example, forms the basis of standard applications such as single molecule tracking and localization-based superresolution image reconstruction. Assuming that the estimator used recovers, on average, the true value of the parameter, its accuracy, or standard deviation, is then at best equal to the square root of the Cramér-Rao lower bound. The Cramér-Rao lower bound can therefore be used as a benchmark in the evaluation of the accuracy of an estimator. Additionally, as its value can be computed and assessed for different experimental settings, it is useful as an experimental design tool. This tutorial demonstrates a mathematical framework that has been specifically developed to calculate the Cramér-Rao lower bound for estimation problems in single molecule microscopy and, more broadly, fluorescence microscopy. The material includes a presentation of the photon detection process that underlies all image data, various image data models that describe images acquired with different detector types, and Fisher information expressions that are necessary for the calculation of the lower bound. Throughout the tutorial, examples involving concrete estimation problems are used to illustrate the effects of various factors on the accuracy of parameter estimation, and more generally, to demonstrate the flexibility of the mathematical framework. PMID:27409706

  20. A Simple Model of Global Aerosol Indirect Effects

    NASA Technical Reports Server (NTRS)

    Ghan, Steven J.; Smith, Steven J.; Wang, Minghuai; Zhang, Kai; Pringle, Kirsty; Carslaw, Kenneth; Pierce, Jeffrey; Bauer, Susanne; Adams, Peter

    2013-01-01

    Most estimates of the global mean indirect effect of anthropogenic aerosol on the Earth's energy balance are from simulations by global models of the aerosol lifecycle coupled with global models of clouds and the hydrologic cycle. Extremely simple models have been developed for integrated assessment models, but lack the flexibility to distinguish between primary and secondary sources of aerosol. Here a simple but more physically based model expresses the aerosol indirect effect (AIE) using analytic representations of cloud and aerosol distributions and processes. Although the simple model is able to produce estimates of AIEs that are comparable to those from some global aerosol models using the same global mean aerosol properties, the estimates by the simple model are sensitive to preindustrial cloud condensation nuclei concentration, preindustrial accumulation mode radius, width of the accumulation mode, size of primary particles, cloud thickness, primary and secondary anthropogenic emissions, the fraction of the secondary anthropogenic emissions that accumulates on the coarse mode, the fraction of the secondary mass that forms new particles, and the sensitivity of liquid water path to droplet number concentration. Estimates of present-day AIEs as low as 5 W/sq m and as high as 0.3 W/sq m are obtained for plausible sets of parameter values. Estimates are surprisingly linear in emissions. The estimates depend on parameter values in ways that are consistent with results from detailed global aerosol-climate simulation models, which adds to understanding of the dependence on AIE uncertainty on uncertainty in parameter values.

  1. Estimation of evapotranspiration in an arid region by remote sensing—A case study in the middle reaches of the Heihe River Basin

    NASA Astrophysics Data System (ADS)

    Li, Xingmin; Lu, Ling; Yang, Wenfeng; Cheng, Guodong

    2012-07-01

    Estimating surface evapotranspiration is extremely important for the study of water resources in arid regions. Data from the National Oceanic and Atmospheric Administration's Advanced Very High Resolution Radiometer (NOAA/AVHRR), meteorological observations and data obtained from the Watershed Allied Telemetry Experimental Research (WATER) project in 2008 are applied to the evaporative fraction model to estimate evapotranspiration over the Heihe River Basin. The calculation method for the parameters used in the model and the evapotranspiration estimation results are analyzed and evaluated. The results observed within the oasis and the banks of the river suggest that more evapotranspiration occurs in the inland river basin in the arid region from May to September. Evapotranspiration values for the oasis, where the land surface types and vegetations are highly variable, are relatively small and heterogeneous. In the Gobi desert and other deserts with little vegetation, evapotranspiration remains at its lowest level during this period. These results reinforce the conclusion that rational utilization of water resources in the oasis is essential to manage the water resources in the inland river basin. In the remote sensing-based evapotranspiration model, the accuracy of the parameter estimate directly affects the accuracy of the evapotranspiration results; more accurate parameter values yield more precise values for evapotranspiration. However, when using the evaporative fraction to estimate regional evapotranspiration, better calculation results can be achieved only if evaporative fraction is constant in the daytime.

  2. Numerical weather prediction model tuning via ensemble prediction system

    NASA Astrophysics Data System (ADS)

    Jarvinen, H.; Laine, M.; Ollinaho, P.; Solonen, A.; Haario, H.

    2011-12-01

    This paper discusses a novel approach to tune predictive skill of numerical weather prediction (NWP) models. NWP models contain tunable parameters which appear in parameterizations schemes of sub-grid scale physical processes. Currently, numerical values of these parameters are specified manually. In a recent dual manuscript (QJRMS, revised) we developed a new concept and method for on-line estimation of the NWP model parameters. The EPPES ("Ensemble prediction and parameter estimation system") method requires only minimal changes to the existing operational ensemble prediction infra-structure and it seems very cost-effective because practically no new computations are introduced. The approach provides an algorithmic decision making tool for model parameter optimization in operational NWP. In EPPES, statistical inference about the NWP model tunable parameters is made by (i) generating each member of the ensemble of predictions using different model parameter values, drawn from a proposal distribution, and (ii) feeding-back the relative merits of the parameter values to the proposal distribution, based on evaluation of a suitable likelihood function against verifying observations. In the presentation, the method is first illustrated in low-order numerical tests using a stochastic version of the Lorenz-95 model which effectively emulates the principal features of ensemble prediction systems. The EPPES method correctly detects the unknown and wrongly specified parameters values, and leads to an improved forecast skill. Second, results with an atmospheric general circulation model based ensemble prediction system show that the NWP model tuning capacity of EPPES scales up to realistic models and ensemble prediction systems. Finally, a global top-end NWP model tuning exercise with preliminary results is published.

  3. Parameter Estimation for Thurstone Choice Models

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vojnovic, Milan; Yun, Seyoung

    We consider the estimation accuracy of individual strength parameters of a Thurstone choice model when each input observation consists of a choice of one item from a set of two or more items (so called top-1 lists). This model accommodates the well-known choice models such as the Luce choice model for comparison sets of two or more items and the Bradley-Terry model for pair comparisons. We provide a tight characterization of the mean squared error of the maximum likelihood parameter estimator. We also provide similar characterizations for parameter estimators defined by a rank-breaking method, which amounts to deducing one ormore » more pair comparisons from a comparison of two or more items, assuming independence of these pair comparisons, and maximizing a likelihood function derived under these assumptions. We also consider a related binary classification problem where each individual parameter takes value from a set of two possible values and the goal is to correctly classify all items within a prescribed classification error. The results of this paper shed light on how the parameter estimation accuracy depends on given Thurstone choice model and the structure of comparison sets. In particular, we found that for unbiased input comparison sets of a given cardinality, when in expectation each comparison set of given cardinality occurs the same number of times, for a broad class of Thurstone choice models, the mean squared error decreases with the cardinality of comparison sets, but only marginally according to a diminishing returns relation. On the other hand, we found that there exist Thurstone choice models for which the mean squared error of the maximum likelihood parameter estimator can decrease much faster with the cardinality of comparison sets. We report empirical evaluation of some claims and key parameters revealed by theory using both synthetic and real-world input data from some popular sport competitions and online labor platforms.« less

  4. Cable Overheating Risk Warning Method Based on Impedance Parameter Estimation in Distribution Network

    NASA Astrophysics Data System (ADS)

    Yu, Zhang; Xiaohui, Song; Jianfang, Li; Fei, Gao

    2017-05-01

    Cable overheating will lead to the cable insulation level reducing, speed up the cable insulation aging, even easy to cause short circuit faults. Cable overheating risk identification and warning is nessesary for distribution network operators. Cable overheating risk warning method based on impedance parameter estimation is proposed in the paper to improve the safty and reliability operation of distribution network. Firstly, cable impedance estimation model is established by using least square method based on the data from distribiton SCADA system to improve the impedance parameter estimation accuracy. Secondly, calculate the threshold value of cable impedance based on the historical data and the forecast value of cable impedance based on the forecasting data in future from distribiton SCADA system. Thirdly, establish risks warning rules library of cable overheating, calculate the cable impedance forecast value and analysis the change rate of impedance, and then warn the overheating risk of cable line based on the overheating risk warning rules library according to the variation relationship between impedance and line temperature rise. Overheating risk warning method is simulated in the paper. The simulation results shows that the method can identify the imedance and forecast the temperature rise of cable line in distribution network accurately. The result of overheating risk warning can provide decision basis for operation maintenance and repair.

  5. Assessing the quality of life history information in publicly available databases.

    PubMed

    Thorson, James T; Cope, Jason M; Patrick, Wesley S

    2014-01-01

    Single-species life history parameters are central to ecological research and management, including the fields of macro-ecology, fisheries science, and ecosystem modeling. However, there has been little independent evaluation of the precision and accuracy of the life history values in global and publicly available databases. We therefore develop a novel method based on a Bayesian errors-in-variables model that compares database entries with estimates from local experts, and we illustrate this process by assessing the accuracy and precision of entries in FishBase, one of the largest and oldest life history databases. This model distinguishes biases among seven life history parameters, two types of information available in FishBase (i.e., published values and those estimated from other parameters), and two taxa (i.e., bony and cartilaginous fishes) relative to values from regional experts in the United States, while accounting for additional variance caused by sex- and region-specific life history traits. For published values in FishBase, the model identifies a small positive bias in natural mortality and negative bias in maximum age, perhaps caused by unacknowledged mortality caused by fishing. For life history values calculated by FishBase, the model identified large and inconsistent biases. The model also demonstrates greatest precision for body size parameters, decreased precision for values derived from geographically distant populations, and greatest between-sex differences in age at maturity. We recommend that our bias and precision estimates be used in future errors-in-variables models as a prior on measurement errors. This approach is broadly applicable to global databases of life history traits and, if used, will encourage further development and improvements in these databases.

  6. Selecting Sensitive Parameter Subsets in Dynamical Models With Application to Biomechanical System Identification.

    PubMed

    Ramadan, Ahmed; Boss, Connor; Choi, Jongeun; Peter Reeves, N; Cholewicki, Jacek; Popovich, John M; Radcliffe, Clark J

    2018-07-01

    Estimating many parameters of biomechanical systems with limited data may achieve good fit but may also increase 95% confidence intervals in parameter estimates. This results in poor identifiability in the estimation problem. Therefore, we propose a novel method to select sensitive biomechanical model parameters that should be estimated, while fixing the remaining parameters to values obtained from preliminary estimation. Our method relies on identifying the parameters to which the measurement output is most sensitive. The proposed method is based on the Fisher information matrix (FIM). It was compared against the nonlinear least absolute shrinkage and selection operator (LASSO) method to guide modelers on the pros and cons of our FIM method. We present an application identifying a biomechanical parametric model of a head position-tracking task for ten human subjects. Using measured data, our method (1) reduced model complexity by only requiring five out of twelve parameters to be estimated, (2) significantly reduced parameter 95% confidence intervals by up to 89% of the original confidence interval, (3) maintained goodness of fit measured by variance accounted for (VAF) at 82%, (4) reduced computation time, where our FIM method was 164 times faster than the LASSO method, and (5) selected similar sensitive parameters to the LASSO method, where three out of five selected sensitive parameters were shared by FIM and LASSO methods.

  7. Prognosis estimation under the light of metabolic tumor parameters on initial FDG-PET/CT in patients with primary extranodal lymphoma

    PubMed Central

    Okuyucu, Kursat; Ozaydın, Sukru; Alagoz, Engin; Ozgur, Gokhan; Oysul, Fahrettin Guven; Ozmen, Ozlem; Tuncel, Murat; Ozturk, Mustafa; Arslan, Nuri

    2016-01-01

    Abstract Background Non-Hodgkin’s lymphomas arising from the tissues other than primary lymphatic organs are named primary extranodal lymphoma. Most of the studies evaluated metabolic tumor parameters in different organs and histopathologic variants of this disease generally for treatment response. We aimed to evaluate the prognostic value of metabolic tumor parameters derived from initial FDG-PET/CT in patients with a medley of primary extranodal lymphoma in this study. Patients and methods There were 67 patients with primary extranodal lymphoma for whom FDG-PET/CT was requested for primary staging. Quantitative PET/CT parameters: maximum standardized uptake value (SUVmax), average standardized uptake value (SUVmean), metabolic tumor volume (MTV) and total lesion glycolysis (TLG) were used to estimate disease-free survival and overall survival. Results SUVmean, MTV and TLG were found statistically significant after multivariate analysis. SUVmean remained significant after ROC curve analysis. Sensitivity and specificity were calculated as 88% and 64%, respectively, when the cut-off value of SUVmean was chosen as 5.15. After the investigation of primary presentation sites and histo-pathological variants according to recurrence, there is no difference amongst the variants. Primary site of extranodal lymphomas however, is statistically important (p = 0.014). Testis and central nervous system lymphomas have higher recurrence rate (62.5%, 73%, respectively). Conclusions High SUVmean, MTV and TLG values obtained from primary staging FDG-PET/CT are potential risk factors for both disease-free survival and overall survival in primary extranodal lymphoma. SUVmean is the most significant one amongst them for estimating recurrence/metastasis. PMID:27904443

  8. Magnetised Strings in Λ-Dominated Anisotropic Universe

    NASA Astrophysics Data System (ADS)

    Goswami, G. K.; Yadav, Anil Kumar; Dewangan, R. N.

    2016-11-01

    In this paper, we have searched the existence of Λ-dominated anisotropic universe filled with magnetized strings. The observed acceleration of universe has been explained by introducing a positive cosmological constant Λ in the Einstein's field equation which is mathematically equivalent to dark energy with equation of state (EOS) parameter set equal to -1. The present values of the matter and the dark energy parameters (Ω m )0 & (ΩΛ)0 are estimated for high red shift (.3 ≤ z ≤ 1.4) SN Ia supernova data's of observed apparent magnitude along with their possible error taken from Union 2.1 compilation. It is found that the best fit value for (Ω m )0 & (ΩΛ)0 are 0.2920 & 0.7076 respectively which are in good agreement with recent astrophysical observations in the latest surveys like WMAP and Plank. Various physical parameters such as the matter and dark energy densities, the present age of the universe and the present value of deceleration parameter have been obtained on the basis of the values of (Ω m )0 & (ΩΛ)0.Also, we have estimated that the acceleration would have begun in the past at z = 0.6845 i. e. 6.2341 Gyrs before from now.

  9. Aerodynamic parameters of High-Angle-of attack Research Vehicle (HARV) estimated from flight data

    NASA Technical Reports Server (NTRS)

    Klein, Vladislav; Ratvasky, Thomas R.; Cobleigh, Brent R.

    1990-01-01

    Aerodynamic parameters of the High-Angle-of-Attack Research Aircraft (HARV) were estimated from flight data at different values of the angle of attack between 10 degrees and 50 degrees. The main part of the data was obtained from small amplitude longitudinal and lateral maneuvers. A small number of large amplitude maneuvers was also used in the estimation. The measured data were first checked for their compatibility. It was found that the accuracy of air data was degraded by unexplained bias errors. Then, the data were analyzed by a stepwise regression method for obtaining a structure of aerodynamic model equations and least squares parameter estimates. Because of high data collinearity in several maneuvers, some of the longitudinal and all lateral maneuvers were reanalyzed by using two biased estimation techniques, the principal components regression and mixed estimation. The estimated parameters in the form of stability and control derivatives, and aerodynamic coefficients were plotted against the angle of attack and compared with the wind tunnel measurements. The influential parameters are, in general, estimated with acceptable accuracy and most of them are in agreement with wind tunnel results. The simulated responses of the aircraft showed good prediction capabilities of the resulting model.

  10. Nitrous oxide emissions from cropland: a procedure for calibrating the DayCent biogeochemical model using inverse modelling

    USGS Publications Warehouse

    Rafique, Rashad; Fienen, Michael N.; Parkin, Timothy B.; Anex, Robert P.

    2013-01-01

    DayCent is a biogeochemical model of intermediate complexity widely used to simulate greenhouse gases (GHG), soil organic carbon and nutrients in crop, grassland, forest and savannah ecosystems. Although this model has been applied to a wide range of ecosystems, it is still typically parameterized through a traditional “trial and error” approach and has not been calibrated using statistical inverse modelling (i.e. algorithmic parameter estimation). The aim of this study is to establish and demonstrate a procedure for calibration of DayCent to improve estimation of GHG emissions. We coupled DayCent with the parameter estimation (PEST) software for inverse modelling. The PEST software can be used for calibration through regularized inversion as well as model sensitivity and uncertainty analysis. The DayCent model was analysed and calibrated using N2O flux data collected over 2 years at the Iowa State University Agronomy and Agricultural Engineering Research Farms, Boone, IA. Crop year 2003 data were used for model calibration and 2004 data were used for validation. The optimization of DayCent model parameters using PEST significantly reduced model residuals relative to the default DayCent parameter values. Parameter estimation improved the model performance by reducing the sum of weighted squared residual difference between measured and modelled outputs by up to 67 %. For the calibration period, simulation with the default model parameter values underestimated mean daily N2O flux by 98 %. After parameter estimation, the model underestimated the mean daily fluxes by 35 %. During the validation period, the calibrated model reduced sum of weighted squared residuals by 20 % relative to the default simulation. Sensitivity analysis performed provides important insights into the model structure providing guidance for model improvement.

  11. Safety assessment of a shallow foundation using the random finite element method

    NASA Astrophysics Data System (ADS)

    Zaskórski, Łukasz; Puła, Wojciech

    2015-04-01

    A complex structure of soil and its random character are reasons why soil modeling is a cumbersome task. Heterogeneity of soil has to be considered even within a homogenous layer of soil. Therefore an estimation of shear strength parameters of soil for the purposes of a geotechnical analysis causes many problems. In applicable standards (Eurocode 7) there is not presented any explicit method of an evaluation of characteristic values of soil parameters. Only general guidelines can be found how these values should be estimated. Hence many approaches of an assessment of characteristic values of soil parameters are presented in literature and can be applied in practice. In this paper, the reliability assessment of a shallow strip footing was conducted using a reliability index β. Therefore some approaches of an estimation of characteristic values of soil properties were compared by evaluating values of reliability index β which can be achieved by applying each of them. Method of Orr and Breysse, Duncan's method, Schneider's method, Schneider's method concerning influence of fluctuation scales and method included in Eurocode 7 were examined. Design values of the bearing capacity based on these approaches were referred to the stochastic bearing capacity estimated by the random finite element method (RFEM). Design values of the bearing capacity were conducted for various widths and depths of a foundation in conjunction with design approaches DA defined in Eurocode. RFEM was presented by Griffiths and Fenton (1993). It combines deterministic finite element method, random field theory and Monte Carlo simulations. Random field theory allows to consider a random character of soil parameters within a homogenous layer of soil. For this purpose a soil property is considered as a separate random variable in every element of a mesh in the finite element method with proper correlation structure between points of given area. RFEM was applied to estimate which theoretical probability distribution fits the empirical probability distribution of bearing capacity basing on 3000 realizations. Assessed probability distribution was applied to compute design values of the bearing capacity and related reliability indices β. Conducted analysis were carried out for a cohesion soil. Hence a friction angle and a cohesion were defined as a random parameters and characterized by two dimensional random fields. A friction angle was described by a bounded distribution as it differs within limited range. While a lognormal distribution was applied in case of a cohesion. Other properties - Young's modulus, Poisson's ratio and unit weight were assumed as deterministic values because they have negligible influence on the stochastic bearing capacity. Griffiths D. V., & Fenton G. A. (1993). Seepage beneath water retaining structures founded on spatially random soil. Géotechnique, 43(6), 577-587.

  12. Geoelectrohydraulic investigation of the surficial aquifer units and corrosivity in parts of Uyo L. G. A., Akwa Ibom State, Southern Nigeria

    NASA Astrophysics Data System (ADS)

    Ibuot, Johnson C.; Obiora, Daniel N.; Ekpa, Moses M. M.; Okoroh, Doris O.

    2017-12-01

    This study was carried out employing vertical electrical sounding (VES) with Schlumberger electrode configuration. The objectives were to investigate the distribution of the geohydraulic parameters and the corrosivity of the aquifer layer within the study area. The sand-to-coarse grain sands aquifer have resistivity ranging from 8.1 to 2204 Ωm, while the thickness ranged from 7.4 to 55.3 m. These parameters were used in computing the geohydraulic parameters. Hydraulic conductivity was estimated using the Heigold equation, and its values ranged from 1.42 to 54.90 m/day. Estimated hydraulic conductivity values were employed in determining the aquifer transmissivity which ranged from 11.28 to 812.00 m2/day, fractional porosities ranged from 0.0351 to 0.0598. The longitudinarl conductance also varies from 0.01 to 1.83 Ω-1. The contour plots generated from the SURFER software package show the variation of these parameters. The ranges of these estimated parameters indicate variation in grain sizes, magnitude of pore sizes and facies changes. The corrosivity rating indicates that most of the VES points were practically non-corrosive.

  13. Coda Q Attenuation and Source Parameters Analysis in North East India Using Local Earthquakes

    NASA Astrophysics Data System (ADS)

    Mohapatra, A. K.; Mohanty, W. K.; Earthquake Seismology

    2010-12-01

    Alok Kumar Mohapatra1* and William Kumar Mohanty1 *Corresponding author: alokgpiitkgp@gmail.com 1Department of Geology and Geophysics, Indian Institute of Technology, Kharagpur, West Bengal, India. Pin-721302 ABSTRACT In the present study, the quality factor of coda waves (Qc) and the source parameters has been estimated for the Northeastern India, using the digital data of ten local earthquakes from April 2001 to November 2002. Earthquakes with magnitude range from 3.8 to 4.9 have been taken into account. The time domain coda decay method of a single back scattering model is used to calculate frequency dependent values of Coda Q (Qc) where as, the source parameters like seismic moment(Mo), stress drop, source radius(r), radiant energy(Wo),and strain drop are estimated using displacement amplitude spectrum of body wave using Brune's model. The earthquakes with magnitude range 3.8 to 4.9 have been used for estimation Qc at six central frequencies 1.5 Hz, 3.0 Hz, 6.0 Hz, 9.0 Hz, 12.0 Hz, and 18.0 Hz. In the present work, the Qc value of local earthquakes are estimated to understand the attenuation characteristic, source parameters and tectonic activity of the region. Based on a criteria of homogeneity in the geological characteristics and the constrains imposed by the distribution of available events the study region has been classified into three zones such as the Tibetan Plateau Zone (TPZ), Bengal Alluvium and Arakan-Yuma Zone (BAZ), Shillong Plateau Zone (SPZ). It follows the power law Qc= Qo (f/fo)n where, Qo is the quality factor at the reference frequency (1Hz) fo and n is the frequency parameter which varies from region to region. The mean values of Qc reveals a dependence on frequency, varying from 292.9 at 1.5 Hz to 4880.1 at 18 Hz. Average frequency dependent relationship Qc values obtained of the Northeastern India is 198 f 1.035, while this relationship varies from the region to region such as, Tibetan Plateau Zone (TPZ): Qc= 226 f 1.11, Bengal Alluvium and Arakan-Yuma Zone (BAZ) : Qc= 301 f 0.87, Shillong Plateau Zone (SPZ): Qc=126 fo 0.85. It indicates Northeastern India is seismically active but comparing of all zones in the study region the Shillong Plateau Zone (SPZ): Qc= 126 f 0.85 is seismically most active. Where as the Bengal Alluvium and Arakan-Yuma Zone (BAZ) are less active and out of three the Tibetan Plateau Zone (TPZ)is intermediate active. This study may be useful for the seismic hazard assessment. The estimated seismic moments (Mo), range from 5.98×1020 to 3.88×1023 dyne-cm. The source radii(r) are confined between 152 to 1750 meter, the stress drop ranges between 0.0003×103 bar to 1.04×103 bar, the average radiant energy is 82.57×1018 ergs and the strain drop for the earthquake ranges from 0.00602×10-9 to 2.48×10-9 respectively. The estimated stress drop values for NE India depicts scattered nature of the larger seismic moment value whereas, they show a more systematic nature for smaller seismic moment values. The estimated source parameters are in agreement to previous works in this type of tectonic set up. Key words: Coda wave, Seismic source parameters, Lapse time, single back scattering model, Brune's model, Stress drop and North East India.

  14. The Estimation of Compaction Parameter Values Based on Soil Properties Values Stabilized with Portland Cement

    NASA Astrophysics Data System (ADS)

    Lubis, A. S.; Muis, Z. A.; Pasaribu, M. I.

    2017-03-01

    The strength and durability of pavement construction is highly dependent on the properties and subgrade bearing capacity. This then led to the idea of the selection methods to estimate the density of the soil with the proper implementation of the system, fast and economical. This study aims to estimate the compaction parameter value namely the maximum dry unit weight (γd max) and optimum moisture content (wopt) of the soil properties value that stabilized with Portland Cement. Tests conducted in the laboratory of soil mechanics to determine the index properties (fines and liquid limit) and Standard Compaction Test. Soil samples that have Plasticity Index (PI) between 0-15% then mixed with Portland Cement (PC) with variations of 2%, 4%, 6%, 8% and 10%, each 10 samples. The results showed that the maximum dry unit weight (γd max) and wopt has a significant relationship with percent fines, liquid limit and the percentation of cement. Equation for the estimated maximum dry unit weight (γd max) = 1.782 - 0.011*LL + 0,000*F + 0.006*PS with R2 = 0.915 and the estimated optimum moisture content (wopt) = 3.441 + 0.594*LL + 0,025*F + 0,024*PS with R2 = 0.726.

  15. Estimation of Gravity Parameters Related to Simple Geometrical Structures by Developing an Approach Based on Deconvolution and Linear Optimization Techniques

    NASA Astrophysics Data System (ADS)

    Asfahani, J.; Tlas, M.

    2015-10-01

    An easy and practical method for interpreting residual gravity anomalies due to simple geometrically shaped models such as cylinders and spheres has been proposed in this paper. This proposed method is based on both the deconvolution technique and the simplex algorithm for linear optimization to most effectively estimate the model parameters, e.g., the depth from the surface to the center of a buried structure (sphere or horizontal cylinder) or the depth from the surface to the top of a buried object (vertical cylinder), and the amplitude coefficient from the residual gravity anomaly profile. The method was tested on synthetic data sets corrupted by different white Gaussian random noise levels to demonstrate the capability and reliability of the method. The results acquired show that the estimated parameter values derived by this proposed method are close to the assumed true parameter values. The validity of this method is also demonstrated using real field residual gravity anomalies from Cuba and Sweden. Comparable and acceptable agreement is shown between the results derived by this method and those derived from real field data.

  16. Parameters Estimation of Geographically Weighted Ordinal Logistic Regression (GWOLR) Model

    NASA Astrophysics Data System (ADS)

    Zuhdi, Shaifudin; Retno Sari Saputro, Dewi; Widyaningsih, Purnami

    2017-06-01

    A regression model is the representation of relationship between independent variable and dependent variable. The dependent variable has categories used in the logistic regression model to calculate odds on. The logistic regression model for dependent variable has levels in the logistics regression model is ordinal. GWOLR model is an ordinal logistic regression model influenced the geographical location of the observation site. Parameters estimation in the model needed to determine the value of a population based on sample. The purpose of this research is to parameters estimation of GWOLR model using R software. Parameter estimation uses the data amount of dengue fever patients in Semarang City. Observation units used are 144 villages in Semarang City. The results of research get GWOLR model locally for each village and to know probability of number dengue fever patient categories.

  17. Model-Based IN SITU Parameter Estimation of Ultrasonic Guided Waves in AN Isotropic Plate

    NASA Astrophysics Data System (ADS)

    Hall, James S.; Michaels, Jennifer E.

    2010-02-01

    Most ultrasonic systems employing guided waves for flaw detection require information such as dispersion curves, transducer locations, and expected propagation loss. Degraded system performance may result if assumed parameter values do not accurately reflect the actual environment. By characterizing the propagating environment in situ at the time of test, potentially erroneous a priori estimates are avoided and performance of ultrasonic guided wave systems can be improved. A four-part model-based algorithm is described in the context of previous work that estimates model parameters whereby an assumed propagation model is used to describe the received signals. This approach builds upon previous work by demonstrating the ability to estimate parameters for the case of single mode propagation. Performance is demonstrated on signals obtained from theoretical dispersion curves, finite element modeling, and experimental data.

  18. Assessing Interval Estimation Methods for Hill Model ...

    EPA Pesticide Factsheets

    The Hill model of concentration-response is ubiquitous in toxicology, perhaps because its parameters directly relate to biologically significant metrics of toxicity such as efficacy and potency. Point estimates of these parameters obtained through least squares regression or maximum likelihood are commonly used in high-throughput risk assessment, but such estimates typically fail to include reliable information concerning confidence in (or precision of) the estimates. To address this issue, we examined methods for assessing uncertainty in Hill model parameter estimates derived from concentration-response data. In particular, using a sample of ToxCast concentration-response data sets, we applied four methods for obtaining interval estimates that are based on asymptotic theory, bootstrapping (two varieties), and Bayesian parameter estimation, and then compared the results. These interval estimation methods generally did not agree, so we devised a simulation study to assess their relative performance. We generated simulated data by constructing four statistical error models capable of producing concentration-response data sets comparable to those observed in ToxCast. We then applied the four interval estimation methods to the simulated data and compared the actual coverage of the interval estimates to the nominal coverage (e.g., 95%) in order to quantify performance of each of the methods in a variety of cases (i.e., different values of the true Hill model paramet

  19. stochastic estimation of transmissivity fields conditioned to flow connectivity data

    NASA Astrophysics Data System (ADS)

    Freixas, Genis; Fernàndez-Garcia, Daniel; Sanchez-vila, Xavier

    2017-04-01

    Most methods for hydraulic parameter interpretation rely on a number of simplifications regarding the homogeneity of the underlying porous media. This way, the actual heterogeneity of any natural parameter, such as transmissivity, is transferred to the estimated in a way heavily dependent on the interpretation method used. An example is a pumping test, in most cases interpreted by means of the Cooper-Jacob method, which implicitly assumes a homogeneous isotropic confined aquifer. It was shown that the estimates obtained from this method when applied to a real site are not local values, but still have a physical meaning; the estimated transmissivity is equal to the effective transmissivity characteristic of the regional scale, while the log-ratio of the estimated storage coefficient with respect to the actual real value (assumed constant), indicated by , is an indicator of flow connectivity, representative of the scale given by the distance between the pumping and the observation wells. In this work we propose a methodology to use together with actual measurements of the log transmissivity at selected points to obtain a map of the best local transmissivity estimates using cokriging. Since the interpolation involves two variables measured at different support scales, a critical point is the estimation of the covariance and crosscovariance matrices, involving some quadratures that are obtained using some simplified approach. The method was applied to a synthetic field displaying statistical anisotropy, showing that the use of connectivity indicators mixed with the local values provide a better representation of the local value map, in particular regarding the enhanced representation of the continuity of structures corresponding to either high or low values.

  20. UCODE_2005 and six other computer codes for universal sensitivity analysis, calibration, and uncertainty evaluation constructed using the JUPITER API

    USGS Publications Warehouse

    Poeter, Eileen E.; Hill, Mary C.; Banta, Edward R.; Mehl, Steffen; Christensen, Steen

    2006-01-01

    This report documents the computer codes UCODE_2005 and six post-processors. Together the codes can be used with existing process models to perform sensitivity analysis, data needs assessment, calibration, prediction, and uncertainty analysis. Any process model or set of models can be used; the only requirements are that models have numerical (ASCII or text only) input and output files, that the numbers in these files have sufficient significant digits, that all required models can be run from a single batch file or script, and that simulated values are continuous functions of the parameter values. Process models can include pre-processors and post-processors as well as one or more models related to the processes of interest (physical, chemical, and so on), making UCODE_2005 extremely powerful. An estimated parameter can be a quantity that appears in the input files of the process model(s), or a quantity used in an equation that produces a value that appears in the input files. In the latter situation, the equation is user-defined. UCODE_2005 can compare observations and simulated equivalents. The simulated equivalents can be any simulated value written in the process-model output files or can be calculated from simulated values with user-defined equations. The quantities can be model results, or dependent variables. For example, for ground-water models they can be heads, flows, concentrations, and so on. Prior, or direct, information on estimated parameters also can be considered. Statistics are calculated to quantify the comparison of observations and simulated equivalents, including a weighted least-squares objective function. In addition, data-exchange files are produced that facilitate graphical analysis. UCODE_2005 can be used fruitfully in model calibration through its sensitivity analysis capabilities and its ability to estimate parameter values that result in the best possible fit to the observations. Parameters are estimated using nonlinear regression: a weighted least-squares objective function is minimized with respect to the parameter values using a modified Gauss-Newton method or a double-dogleg technique. Sensitivities needed for the method can be read from files produced by process models that can calculate sensitivities, such as MODFLOW-2000, or can be calculated by UCODE_2005 using a more general, but less accurate, forward- or central-difference perturbation technique. Problems resulting from inaccurate sensitivities and solutions related to the perturbation techniques are discussed in the report. Statistics are calculated and printed for use in (1) diagnosing inadequate data and identifying parameters that probably cannot be estimated; (2) evaluating estimated parameter values; and (3) evaluating how well the model represents the simulated processes. Results from UCODE_2005 and codes RESIDUAL_ANALYSIS and RESIDUAL_ANALYSIS_ADV can be used to evaluate how accurately the model represents the processes it simulates. Results from LINEAR_UNCERTAINTY can be used to quantify the uncertainty of model simulated values if the model is sufficiently linear. Results from MODEL_LINEARITY and MODEL_LINEARITY_ADV can be used to evaluate model linearity and, thereby, the accuracy of the LINEAR_UNCERTAINTY results. UCODE_2005 can also be used to calculate nonlinear confidence and predictions intervals, which quantify the uncertainty of model simulated values when the model is not linear. CORFAC_PLUS can be used to produce factors that allow intervals to account for model intrinsic nonlinearity and small-scale variations in system characteristics that are not explicitly accounted for in the model or the observation weighting. The six post-processing programs are independent of UCODE_2005 and can use the results of other programs that produce the required data-exchange files. UCODE_2005 and the other six codes are intended for use on any computer operating system. The programs con

  1. Aerodynamic Parameter Estimation for the X-43A (Hyper-X) from Flight Data

    NASA Technical Reports Server (NTRS)

    Morelli, Eugene A.; Derry, Stephen D.; Smith, Mark S.

    2005-01-01

    Aerodynamic parameters were estimated based on flight data from the third flight of the X-43A hypersonic research vehicle, also called Hyper-X. Maneuvers were flown using multiple orthogonal phase-optimized sweep inputs applied as simultaneous control surface perturbations at Mach 8, 7, 6, 5, 4, and 3 during the vehicle descent. Aerodynamic parameters, consisting of non-dimensional longitudinal and lateral stability and control derivatives, were estimated from flight data at each Mach number. Multi-step inputs at nearly the same flight conditions were also flown to assess the prediction capability of the identified models. Prediction errors were found to be comparable in magnitude to the modeling errors, which indicates accurate modeling. Aerodynamic parameter estimates were plotted as a function of Mach number, and compared with estimates from the pre-flight aerodynamic database, which was based on wind-tunnel tests and computational fluid dynamics. Agreement between flight estimates and values computed from the aerodynamic database was excellent overall.

  2. Examining the effect of initialization strategies on the performance of Gaussian mixture modeling.

    PubMed

    Shireman, Emilie; Steinley, Douglas; Brusco, Michael J

    2017-02-01

    Mixture modeling is a popular technique for identifying unobserved subpopulations (e.g., components) within a data set, with Gaussian (normal) mixture modeling being the form most widely used. Generally, the parameters of these Gaussian mixtures cannot be estimated in closed form, so estimates are typically obtained via an iterative process. The most common estimation procedure is maximum likelihood via the expectation-maximization (EM) algorithm. Like many approaches for identifying subpopulations, finite mixture modeling can suffer from locally optimal solutions, and the final parameter estimates are dependent on the initial starting values of the EM algorithm. Initial values have been shown to significantly impact the quality of the solution, and researchers have proposed several approaches for selecting the set of starting values. Five techniques for obtaining starting values that are implemented in popular software packages are compared. Their performances are assessed in terms of the following four measures: (1) the ability to find the best observed solution, (2) settling on a solution that classifies observations correctly, (3) the number of local solutions found by each technique, and (4) the speed at which the start values are obtained. On the basis of these results, a set of recommendations is provided to the user.

  3. Supersensitive ancilla-based adaptive quantum phase estimation

    NASA Astrophysics Data System (ADS)

    Larson, Walker; Saleh, Bahaa E. A.

    2017-10-01

    The supersensitivity attained in quantum phase estimation is known to be compromised in the presence of decoherence. This is particularly patent at blind spots—phase values at which sensitivity is totally lost. One remedy is to use a precisely known reference phase to shift the operation point to a less vulnerable phase value. Since this is not always feasible, we present here an alternative approach based on combining the probe with an ancillary degree of freedom containing adjustable parameters to create an entangled quantum state of higher dimension. We validate this concept by simulating a configuration of a Mach-Zehnder interferometer with a two-photon probe and a polarization ancilla of adjustable parameters, entangled at a polarizing beam splitter. At the interferometer output, the photons are measured after an adjustable unitary transformation in the polarization subspace. Through calculation of the Fisher information and simulation of an estimation procedure, we show that optimizing the adjustable polarization parameters using an adaptive measurement process provides globally supersensitive unbiased phase estimates for a range of decoherence levels, without prior information or a reference phase.

  4. Unified Least Squares Methods for the Evaluation of Diagnostic Tests With the Gold Standard

    PubMed Central

    Tang, Liansheng Larry; Yuan, Ao; Collins, John; Che, Xuan; Chan, Leighton

    2017-01-01

    The article proposes a unified least squares method to estimate the receiver operating characteristic (ROC) parameters for continuous and ordinal diagnostic tests, such as cancer biomarkers. The method is based on a linear model framework using the empirically estimated sensitivities and specificities as input “data.” It gives consistent estimates for regression and accuracy parameters when the underlying continuous test results are normally distributed after some monotonic transformation. The key difference between the proposed method and the method of Tang and Zhou lies in the response variable. The response variable in the latter is transformed empirical ROC curves at different thresholds. It takes on many values for continuous test results, but few values for ordinal test results. The limited number of values for the response variable makes it impractical for ordinal data. However, the response variable in the proposed method takes on many more distinct values so that the method yields valid estimates for ordinal data. Extensive simulation studies are conducted to investigate and compare the finite sample performance of the proposed method with an existing method, and the method is then used to analyze 2 real cancer diagnostic example as an illustration. PMID:28469385

  5. Identifying Bearing Rotordynamic Coefficients using an Extended Kalman Filter

    NASA Technical Reports Server (NTRS)

    Miller, Brad A.; Howard, Samuel A.

    2008-01-01

    An Extended Kalman Filter is developed to estimate the linearized direct and indirect stiffness and damping force coefficients for bearings in rotor-dynamic applications from noisy measurements of the shaft displacement in response to imbalance and impact excitation. The bearing properties are modeled as stochastic random variables using a Gauss-Markov model. Noise terms are introduced into the system model to account for all of the estimation error, including modeling errors and uncertainties and the propagation of measurement errors into the parameter estimates. The system model contains two user-defined parameters that can be tuned to improve the filter s performance; these parameters correspond to the covariance of the system and measurement noise variables. The filter is also strongly influenced by the initial values of the states and the error covariance matrix. The filter is demonstrated using numerically simulated data for a rotor-bearing system with two identical bearings, which reduces the number of unknown linear dynamic coefficients to eight. The filter estimates for the direct damping coefficients and all four stiffness coefficients correlated well with actual values, whereas the estimates for the cross-coupled damping coefficients were the least accurate.

  6. A means to estimate thermal and kinetic parameters of coal dust layer from hot surface ignition tests.

    PubMed

    Park, Haejun; Rangwala, Ali S; Dembsey, Nicholas A

    2009-08-30

    A method to estimate thermal and kinetic parameters of Pittsburgh seam coal subject to thermal runaway is presented using the standard ASTM E 2021 hot surface ignition test apparatus. Parameters include thermal conductivity (k), activation energy (E), coupled term (QA) of heat of reaction (Q) and pre-exponential factor (A) which are required, but rarely known input values to determine the thermal runaway propensity of a dust material. Four different dust layer thicknesses: 6.4, 12.7, 19.1 and 25.4mm, are tested, and among them, a single steady state dust layer temperature profile of 12.7 mm thick dust layer is used to estimate k, E and QA. k is calculated by equating heat flux from the hot surface layer and heat loss rate on the boundary assuming negligible heat generation in the coal dust layer at a low hot surface temperature. E and QA are calculated by optimizing a numerically estimated steady state dust layer temperature distribution to the experimentally obtained temperature profile of a 12.7 mm thick dust layer. Two unknowns, E and QA, are reduced to one from the correlation of E and QA obtained at criticality of thermal runaway. The estimated k is 0.1 W/mK matching the previously reported value. E ranges from 61.7 to 83.1 kJ/mol, and the corresponding QA ranges from 1.7 x 10(9) to 4.8 x 10(11)J/kg s. The mean values of E (72.4 kJ/mol) and QA (2.8 x 10(10)J/kg s) are used to predict the critical hot surface temperatures for other thicknesses, and good agreement is observed between measured and experimental values. Also, the estimated E and QA ranges match the corresponding ranges calculated from the multiple tests method and values reported in previous research.

  7. Comparison of Ionospheric Parameters during Similar Geomagnetic Storms

    NASA Astrophysics Data System (ADS)

    Blagoveshchensky, D. V.

    2018-03-01

    The degree of closeness of ionospheric parameters during one magnetic storm and of the same parameters during another, similar, storm is estimated. Overall, four storms—two pairs of storms close in structure and appearance according to recording of the magnetic field X-component—were analyzed. The examination was based on data from Sodankyla observatory (Finland). The f-graphs of the ionospheric vertical sounding, magnetometer data, and riometer data on absorption were used. The main results are as follows. The values of the critical frequencies foF2, foF1, and foE for different but similar magnetic storms differ insignificantly. In the daytime, the difference is on average 6% (from 0 to 11.1%) for all ionospheric layers. In the nighttime conditions, the difference for foF2 is 4%. The nighttime values of foEs differ on average by 20%. These estimates potentially make it possible to forecast ionospheric parameters for a particular storm.

  8. Comparison of spectral estimators for characterizing fractionated atrial electrograms

    PubMed Central

    2013-01-01

    Background Complex fractionated atrial electrograms (CFAE) acquired during atrial fibrillation (AF) are commonly assessed using the discrete Fourier transform (DFT), but this can lead to inaccuracy. In this study, spectral estimators derived by averaging the autocorrelation function at lags were compared to the DFT. Method Bipolar CFAE of at least 16 s duration were obtained from pulmonary vein ostia and left atrial free wall sites (9 paroxysmal and 10 persistent AF patients). Power spectra were computed using the DFT and three other methods: 1. a novel spectral estimator based on signal averaging (NSE), 2. the NSE with harmonic removal (NSH), and 3. the autocorrelation function average at lags (AFA). Three spectral parameters were calculated: 1. the largest fundamental spectral peak, known as the dominant frequency (DF), 2. the DF amplitude (DA), and 3. the mean spectral profile (MP), which quantifies noise floor level. For each spectral estimator and parameter, the significance of the difference between paroxysmal and persistent AF was determined. Results For all estimators, mean DA and mean DF values were higher in persistent AF, while the mean MP value was higher in paroxysmal AF. The differences in means between paroxysmals and persistents were highly significant for 3/3 NSE and NSH measurements and for 2/3 DFT and AFA measurements (p<0.001). For all estimators, the standard deviation in DA and MP values were higher in persistent AF, while the standard deviation in DF value was higher in paroxysmal AF. Differences in standard deviations between paroxysmals and persistents were highly significant in 2/3 NSE and NSH measurements, in 1/3 AFA measurements, and in 0/3 DFT measurements. Conclusions Measurements made from all four spectral estimators were in agreement as to whether the means and standard deviations in three spectral parameters were greater in CFAEs acquired from paroxysmal or in persistent AF patients. Since the measurements were consistent, use of two or more of these estimators for power spectral analysis can be assistive to evaluate CFAE more objectively and accurately, which may lead to improved clinical outcome. Since the most significant differences overall were achieved using the NSE and NSH estimators, parameters measured from their spectra will likely be the most useful for detecting and discerning electrophysiologic differences in the AF substrate based upon frequency analysis of CFAE. PMID:23855345

  9. Parameter estimation of variable-parameter nonlinear Muskingum model using excel solver

    NASA Astrophysics Data System (ADS)

    Kang, Ling; Zhou, Liwei

    2018-02-01

    Abstract . The Muskingum model is an effective flood routing technology in hydrology and water resources Engineering. With the development of optimization technology, more and more variable-parameter Muskingum models were presented to improve effectiveness of the Muskingum model in recent decades. A variable-parameter nonlinear Muskingum model (NVPNLMM) was proposed in this paper. According to the results of two real and frequently-used case studies by various models, the NVPNLMM could obtain better values of evaluation criteria, which are used to describe the superiority of the estimated outflows and compare the accuracies of flood routing using various models, and the optimal estimated outflows by the NVPNLMM were closer to the observed outflows than the ones by other models.

  10. An improved hybrid of particle swarm optimization and the gravitational search algorithm to produce a kinetic parameter estimation of aspartate biochemical pathways.

    PubMed

    Ismail, Ahmad Muhaimin; Mohamad, Mohd Saberi; Abdul Majid, Hairudin; Abas, Khairul Hamimah; Deris, Safaai; Zaki, Nazar; Mohd Hashim, Siti Zaiton; Ibrahim, Zuwairie; Remli, Muhammad Akmal

    2017-12-01

    Mathematical modelling is fundamental to understand the dynamic behavior and regulation of the biochemical metabolisms and pathways that are found in biological systems. Pathways are used to describe complex processes that involve many parameters. It is important to have an accurate and complete set of parameters that describe the characteristics of a given model. However, measuring these parameters is typically difficult and even impossible in some cases. Furthermore, the experimental data are often incomplete and also suffer from experimental noise. These shortcomings make it challenging to identify the best-fit parameters that can represent the actual biological processes involved in biological systems. Computational approaches are required to estimate these parameters. The estimation is converted into multimodal optimization problems that require a global optimization algorithm that can avoid local solutions. These local solutions can lead to a bad fit when calibrating with a model. Although the model itself can potentially match a set of experimental data, a high-performance estimation algorithm is required to improve the quality of the solutions. This paper describes an improved hybrid of particle swarm optimization and the gravitational search algorithm (IPSOGSA) to improve the efficiency of a global optimum (the best set of kinetic parameter values) search. The findings suggest that the proposed algorithm is capable of narrowing down the search space by exploiting the feasible solution areas. Hence, the proposed algorithm is able to achieve a near-optimal set of parameters at a fast convergence speed. The proposed algorithm was tested and evaluated based on two aspartate pathways that were obtained from the BioModels Database. The results show that the proposed algorithm outperformed other standard optimization algorithms in terms of accuracy and near-optimal kinetic parameter estimation. Nevertheless, the proposed algorithm is only expected to work well in small scale systems. In addition, the results of this study can be used to estimate kinetic parameter values in the stage of model selection for different experimental conditions. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Potential application of item-response theory to interpretation of medical codes in electronic patient records

    PubMed Central

    2011-01-01

    Background Electronic patient records are generally coded using extensive sets of codes but the significance of the utilisation of individual codes may be unclear. Item response theory (IRT) models are used to characterise the psychometric properties of items included in tests and questionnaires. This study asked whether the properties of medical codes in electronic patient records may be characterised through the application of item response theory models. Methods Data were provided by a cohort of 47,845 participants from 414 family practices in the UK General Practice Research Database (GPRD) with a first stroke between 1997 and 2006. Each eligible stroke code, out of a set of 202 OXMIS and Read codes, was coded as either recorded or not recorded for each participant. A two parameter IRT model was fitted using marginal maximum likelihood estimation. Estimated parameters from the model were considered to characterise each code with respect to the latent trait of stroke diagnosis. The location parameter is referred to as a calibration parameter, while the slope parameter is referred to as a discrimination parameter. Results There were 79,874 stroke code occurrences available for analysis. Utilisation of codes varied between family practices with intraclass correlation coefficients of up to 0.25 for the most frequently used codes. IRT analyses were restricted to 110 Read codes. Calibration and discrimination parameters were estimated for 77 (70%) codes that were endorsed for 1,942 stroke patients. Parameters were not estimated for the remaining more frequently used codes. Discrimination parameter values ranged from 0.67 to 2.78, while calibration parameters values ranged from 4.47 to 11.58. The two parameter model gave a better fit to the data than either the one- or three-parameter models. However, high chi-square values for about a fifth of the stroke codes were suggestive of poor item fit. Conclusion The application of item response theory models to coded electronic patient records might potentially contribute to identifying medical codes that offer poor discrimination or low calibration. This might indicate the need for improved coding sets or a requirement for improved clinical coding practice. However, in this study estimates were only obtained for a small proportion of participants and there was some evidence of poor model fit. There was also evidence of variation in the utilisation of codes between family practices raising the possibility that, in practice, properties of codes may vary for different coders. PMID:22176509

  12. A note on implementation of decaying product correlation structures for quasi-least squares.

    PubMed

    Shults, Justine; Guerra, Matthew W

    2014-08-30

    This note implements an unstructured decaying product matrix via the quasi-least squares approach for estimation of the correlation parameters in the framework of generalized estimating equations. The structure we consider is fairly general without requiring the large number of parameters that are involved in a fully unstructured matrix. It is straightforward to show that the quasi-least squares estimators of the correlation parameters yield feasible values for the unstructured decaying product structure. Furthermore, subject to conditions that are easily checked, the quasi-least squares estimators are valid for longitudinal Bernoulli data. We demonstrate implementation of the structure in a longitudinal clinical trial with both a continuous and binary outcome variable. Copyright © 2014 John Wiley & Sons, Ltd.

  13. Optimisation of dispersion parameters of Gaussian plume model for CO₂ dispersion.

    PubMed

    Liu, Xiong; Godbole, Ajit; Lu, Cheng; Michal, Guillaume; Venton, Philip

    2015-11-01

    The carbon capture and storage (CCS) and enhanced oil recovery (EOR) projects entail the possibility of accidental release of carbon dioxide (CO2) into the atmosphere. To quantify the spread of CO2 following such release, the 'Gaussian' dispersion model is often used to estimate the resulting CO2 concentration levels in the surroundings. The Gaussian model enables quick estimates of the concentration levels. However, the traditionally recommended values of the 'dispersion parameters' in the Gaussian model may not be directly applicable to CO2 dispersion. This paper presents an optimisation technique to obtain the dispersion parameters in order to achieve a quick estimation of CO2 concentration levels in the atmosphere following CO2 blowouts. The optimised dispersion parameters enable the Gaussian model to produce quick estimates of CO2 concentration levels, precluding the necessity to set up and run much more complicated models. Computational fluid dynamics (CFD) models were employed to produce reference CO2 dispersion profiles in various atmospheric stability classes (ASC), different 'source strengths' and degrees of ground roughness. The performance of the CFD models was validated against the 'Kit Fox' field measurements, involving dispersion over a flat horizontal terrain, both with low and high roughness regions. An optimisation model employing a genetic algorithm (GA) to determine the best dispersion parameters in the Gaussian plume model was set up. Optimum values of the dispersion parameters for different ASCs that can be used in the Gaussian plume model for predicting CO2 dispersion were obtained.

  14. On the ab initio evaluation of Hubbard parameters. II. The κ-(BEDT-TTF)2Cu[N(CN)2]Br crystal

    NASA Astrophysics Data System (ADS)

    Fortunelli, Alessandro; Painelli, Anna

    1997-05-01

    A previously proposed approach for the ab initio evaluation of Hubbard parameters is applied to BEDT-TTF dimers. The dimers are positioned according to four geometries taken as the first neighbors from the experimental data on the κ-(BEDT-TTF)2Cu[N(CN)2]Br crystal. RHF-SCF, CAS-SCF and frozen-orbital calculations using the 6-31G** basis set are performed with different values of the total charge, allowing us to derive all the relevant parameters. It is found that the electronic structure of the BEDT-TTF planes is adequately described by the standard Extended Hubbard Model, with the off-diagonal electron-electron interaction terms (X and W) of negligible size. The derived parameters are in good agreement with available experimental data. Comparison with previous theoretical estimates shows that the t values compare well with those obtained from Extended Hückel Theory (whereas the minimal basis set estimates are completely unreliable). On the other hand, the Uaeff values exhibit an appreciable dependence on the chemical environment.

  15. Parameter estimation in 3D affine and similarity transformation: implementation of variance component estimation

    NASA Astrophysics Data System (ADS)

    Amiri-Simkooei, A. R.

    2018-01-01

    Three-dimensional (3D) coordinate transformations, generally consisting of origin shifts, axes rotations, scale changes, and skew parameters, are widely used in many geomatics applications. Although in some geodetic applications simplified transformation models are used based on the assumption of small transformation parameters, in other fields of applications such parameters are indeed large. The algorithms of two recent papers on the weighted total least-squares (WTLS) problem are used for the 3D coordinate transformation. The methodology can be applied to the case when the transformation parameters are generally large of which no approximate values of the parameters are required. Direct linearization of the rotation and scale parameters is thus not required. The WTLS formulation is employed to take into consideration errors in both the start and target systems on the estimation of the transformation parameters. Two of the well-known 3D transformation methods, namely affine (12, 9, and 8 parameters) and similarity (7 and 6 parameters) transformations, can be handled using the WTLS theory subject to hard constraints. Because the method can be formulated by the standard least-squares theory with constraints, the covariance matrix of the transformation parameters can directly be provided. The above characteristics of the 3D coordinate transformation are implemented in the presence of different variance components, which are estimated using the least squares variance component estimation. In particular, the estimability of the variance components is investigated. The efficacy of the proposed formulation is verified on two real data sets.

  16. An inventory of nitrous oxide emissions from agriculture in the UK using the IPCC methodology: emission estimate, uncertainty and sensitivity analysis

    NASA Astrophysics Data System (ADS)

    Brown, L.; Armstrong Brown, S.; Jarvis, S. C.; Syed, B.; Goulding, K. W. T.; Phillips, V. R.; Sneath, R. W.; Pain, B. F.

    Nitrous oxide emission from UK agriculture was estimated, using the IPCC default values of all emission factors and parameters, to be 87 Gg N 2O-N in both 1990 and 1995. This estimate was shown, however, to have an overall uncertainty of 62%. The largest component of the emission (54%) was from the direct (soil) sector. Two of the three emission factors applied within the soil sector, EF1 (direct emission from soil) and EF3 PRP (emission from pasture range and paddock) were amongst the most influential on the total estimate, producing a ±31 and +11% to -17% change in emissions, respectively, when varied through the IPCC range from the default value. The indirect sector (from leached N and deposited ammonia) contributed 29% of the total emission, and had the largest uncertainty (126%). The factors determining the fraction of N leached (Frac LEACH) and emissions from it (EF5), were the two most influential. These parameters are poorly specified and there is great potential to improve the emission estimate for this component. Use of mathematical models (NCYCLE and SUNDIAL) to predict Frac LEACH suggested that the IPCC default value for this parameter may be too high for most situations in the UK. Comparison with other UK-derived inventories suggests that the IPCC methodology may overestimate emission. Although the IPCC approach includes additional components to the other inventories (most notably emission from indirect sources), estimates for the common components (i.e. fertiliser and animals), and emission factors used, are higher than those of other inventories. Whilst it is recognised that the IPCC approach is generalised in order to allow widespread applicability, sufficient data are available to specify at least two of the most influential parameters, i.e. EF1 and Frac LEACH, more accurately, and so provide an improved estimate of nitrous oxide emissions from UK agriculture.

  17. Estimating historical atmospheric mercury concentrations from silver mining and their legacies in present-day surface soil in Potosí, Bolivia

    NASA Astrophysics Data System (ADS)

    Hagan, Nicole; Robins, Nicholas; Hsu-Kim, Heileen; Halabi, Susan; Morris, Mark; Woodall, George; Zhang, Tong; Bacon, Allan; Richter, Daniel De B.; Vandenberg, John

    2011-12-01

    Detailed Spanish records of mercury use and silver production during the colonial period in Potosí, Bolivia were evaluated to estimate atmospheric emissions of mercury from silver smelting. Mercury was used in the silver production process in Potosí and nearly 32,000 metric tons of mercury were released to the environment. AERMOD was used in combination with the estimated emissions to approximate historical air concentrations of mercury from colonial mining operations during 1715, a year of relatively low silver production. Source characteristics were selected from archival documents, colonial maps and images of silver smelters in Potosí and a base case of input parameters was selected. Input parameters were varied to understand the sensitivity of the model to each parameter. Modeled maximum 1-h concentrations were most sensitive to stack height and diameter, whereas an index of community exposure was relatively insensitive to uncertainty in input parameters. Modeled 1-h and long-term concentrations were compared to inhalation reference values for elemental mercury vapor. Estimated 1-h maximum concentrations within 500 m of the silver smelters consistently exceeded present-day occupational inhalation reference values. Additionally, the entire community was estimated to have been exposed to levels of mercury vapor that exceed present-day acute inhalation reference values for the general public. Estimated long-term maximum concentrations of mercury were predicted to substantially exceed the EPA Reference Concentration for areas within 600 m of the silver smelters. A concentration gradient predicted by AERMOD was used to select soil sampling locations along transects in Potosí. Total mercury in soils ranged from 0.105 to 155 mg kg-1, among the highest levels reported for surface soils in the scientific literature. The correlation between estimated air concentrations and measured soil concentrations will guide future research to determine the extent to which the current community of Potosí and vicinity is at risk of adverse health effects from historical mercury contamination.

  18. Parameter identification of thermophilic anaerobic degradation of valerate.

    PubMed

    Flotats, Xavier; Ahring, Birgitte K; Angelidaki, Irini

    2003-01-01

    The considered mathematical model of the decomposition of valerate presents three unknown kinetic parameters, two unknown stoichiometric coefficients, and three unknown initial concentrations for biomass. Applying a structural identifiability study, we concluded that it is necessary to perform simultaneous batch experiments with different initial conditions for estimating these parameters. Four simultaneous batch experiments were conducted at 55 degrees C, characterized by four different initial acetate concentrations. Product inhibition of valerate degradation by acetate was considered. Practical identification was done optimizing the sum of the multiple determination coefficients for all measured state variables and for all experiments simultaneously. The estimated values of kinetic parameters and stoichiometric coefficients were characterized by the parameter correlation matrix, the confidence interval, and the student's t-test at 5% significance level with positive results except for the saturation constant, for which more experiments for improving its identifiability should be conducted. In this article, we discuss kinetic parameter estimation methods.

  19. Estimating stellar effective temperatures and detected angular parameters using stochastic particle swarm optimization

    NASA Astrophysics Data System (ADS)

    Zhang, Chuan-Xin; Yuan, Yuan; Zhang, Hao-Wei; Shuai, Yong; Tan, He-Ping

    2016-09-01

    Considering features of stellar spectral radiation and sky surveys, we established a computational model for stellar effective temperatures, detected angular parameters and gray rates. Using known stellar flux data in some bands, we estimated stellar effective temperatures and detected angular parameters using stochastic particle swarm optimization (SPSO). We first verified the reliability of SPSO, and then determined reasonable parameters that produced highly accurate estimates under certain gray deviation levels. Finally, we calculated 177 860 stellar effective temperatures and detected angular parameters using data from the Midcourse Space Experiment (MSX) catalog. These derived stellar effective temperatures were accurate when we compared them to known values from literatures. This research makes full use of catalog data and presents an original technique for studying stellar characteristics. It proposes a novel method for calculating stellar effective temperatures and detecting angular parameters, and provides theoretical and practical data for finding information about radiation in any band.

  20. Estimation of the discharges of the multiple water level stations by multi-objective optimization

    NASA Astrophysics Data System (ADS)

    Matsumoto, Kazuhiro; Miyamoto, Mamoru; Yamakage, Yuzuru; Tsuda, Morimasa; Yanami, Hitoshi; Anai, Hirokazu; Iwami, Yoichi

    2016-04-01

    This presentation shows two aspects of the parameter identification to estimate the discharges of the multiple water level stations by multi-objective optimization. One is how to adjust the parameters to estimate the discharges accurately. The other is which optimization algorithms are suitable for the parameter identification. Regarding the previous studies, there is a study that minimizes the weighted error of the discharges of the multiple water level stations by single-objective optimization. On the other hand, there are some studies that minimize the multiple error assessment functions of the discharge of a single water level station by multi-objective optimization. This presentation features to simultaneously minimize the errors of the discharges of the multiple water level stations by multi-objective optimization. Abe River basin in Japan is targeted. The basin area is 567.0km2. There are thirteen rainfall stations and three water level stations. Nine flood events are investigated. They occurred from 2005 to 2012 and the maximum discharges exceed 1,000m3/s. The discharges are calculated with PWRI distributed hydrological model. The basin is partitioned into the meshes of 500m x 500m. Two-layer tanks are placed on each mesh. Fourteen parameters are adjusted to estimate the discharges accurately. Twelve of them are the hydrological parameters and two of them are the parameters of the initial water levels of the tanks. Three objective functions are the mean squared errors between the observed and calculated discharges at the water level stations. Latin Hypercube sampling is one of the uniformly sampling algorithms. The discharges are calculated with respect to the parameter values sampled by a simplified version of Latin Hypercube sampling. The observed discharge is surrounded by the calculated discharges. It suggests that it might be possible to estimate the discharge accurately by adjusting the parameters. In a sense, it is true that the discharge of a water level station can be accurately estimated by setting the parameter values optimized to the responding water level station. However, there are some cases that the calculated discharge by setting the parameter values optimized to one water level station does not meet the observed discharge at another water level station. It is important to estimate the discharges of all the water level stations in some degree of accuracy. It turns out to be possible to select the parameter values from the pareto optimal solutions by the condition that all the normalized errors by the minimum error of the responding water level station are under 3. The optimization performance of five implementations of the algorithms and a simplified version of Latin Hypercube sampling are compared. Five implementations are NSGA2 and PAES of an optimization software inspyred and MCO_NSGA2R, MOPSOCD and NSGA2R_NSGA2R of a statistical software R. NSGA2, PAES and MOPSOCD are the optimization algorithms of a genetic algorithm, an evolution strategy and a particle swarm optimization respectively. The number of the evaluations of the objective functions is 10,000. Two implementations of NSGA2 of R outperform the others. They are promising to be suitable for the parameter identification of PWRI distributed hydrological model.

  1. Missing-value estimation using linear and non-linear regression with Bayesian gene selection.

    PubMed

    Zhou, Xiaobo; Wang, Xiaodong; Dougherty, Edward R

    2003-11-22

    Data from microarray experiments are usually in the form of large matrices of expression levels of genes under different experimental conditions. Owing to various reasons, there are frequently missing values. Estimating these missing values is important because they affect downstream analysis, such as clustering, classification and network design. Several methods of missing-value estimation are in use. The problem has two parts: (1) selection of genes for estimation and (2) design of an estimation rule. We propose Bayesian variable selection to obtain genes to be used for estimation, and employ both linear and nonlinear regression for the estimation rule itself. Fast implementation issues for these methods are discussed, including the use of QR decomposition for parameter estimation. The proposed methods are tested on data sets arising from hereditary breast cancer and small round blue-cell tumors. The results compare very favorably with currently used methods based on the normalized root-mean-square error. The appendix is available from http://gspsnap.tamu.edu/gspweb/zxb/missing_zxb/ (user: gspweb; passwd: gsplab).

  2. A Comparison of Normal and Elliptical Estimation Methods in Structural Equation Models.

    ERIC Educational Resources Information Center

    Schumacker, Randall E.; Cheevatanarak, Suchittra

    Monte Carlo simulation compared chi-square statistics, parameter estimates, and root mean square error of approximation values using normal and elliptical estimation methods. Three research conditions were imposed on the simulated data: sample size, population contamination percent, and kurtosis. A Bentler-Weeks structural model established the…

  3. Assessment of spatial distrilbution of porosity and aquifer geohydraulic parameters in parts of the Tertiary - Quaternary hydrogeoresource of south-eastern Nigeria

    NASA Astrophysics Data System (ADS)

    George, N. J.; Akpan, A. E.; Akpan, F. S.

    2017-12-01

    An integrated attempt exploring information deduced from extensive surface resistivity study in three Local Government Areas of Akwa Ibom State, Nigeria and data from hydrogeological sources obtained from water boreholes have been explored to economically estimate porosity and coefficient of permeability/hydraulic conductivity in parts of the clastic Tertiary - Quaternary sediments of the Niger Delta region. Generally, these parameters are predominantly estimated from empirical analysis of core samples and pumping test data generated from boreholes in the laboratory. However, this analysis is not only costly and time consuming, but also limited in areal coverage. The chosen technique employs surface resistivity data, core samples and pumping test data in order to estimate porosity and aquifer hydraulic parameters (transverse resistance, hydraulic conductivity and transmissivity). In correlating the two sets of results, Porosity and hydraulic conductivity were observed to be more elevated near the riverbanks. Empirical models utilising Archie's, Waxman-Smits and Kozeny-Carman Bear relations were employed characterising the formation parameters with wonderfully deduced good fits. The effect of surface conduction occasioned by clay usually disregarded or ignored in Archie's model was estimated to be 2.58 × 10-5 Siemens. This conductance can be used as a corrective factor to the conduction values obtained from Archie's equation. Interpretation aided measures such as graphs, mathematical models and maps which geared towards realistic conclusions and interrelationship between the porosity and other aquifer parameters were generated. The values of the hydraulic conductivity estimated from Waxman-Smits model was approximately 9.6 × 10-5m/s everywhere. This revelation indicates that there is no pronounced change in the quality of the saturating fluid and the geological formations that serve as aquifers even though the porosities were varying. The deciphered parameter relations can be used to estimate geohydraulic parameters in other locations with little or no borehole data.

  4. Recommended Parameter Values for GENII Modeling of Radionuclides in Routine Air and Water Releases

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Snyder, Sandra F.; Arimescu, Carmen; Napier, Bruce A.

    The GENII v2 code is used to estimate dose to individuals or populations from the release of radioactive materials into air or water. Numerous parameter values are required for input into this code. User-defined parameters cover the spectrum from chemical data, meteorological data, agricultural data, and behavioral data. This document is a summary of parameter values that reflect conditions in the United States. Reasonable regional and age-dependent data is summarized. Data availability and quality varies. The set of parameters described address scenarios for chronic air emissions or chronic releases to public waterways. Considerations for the special tritium and carbon-14 modelsmore » are briefly addressed. GENIIv2.10.0 is the current software version that this document supports.« less

  5. Estimation of the ARNO model baseflow parameters using daily streamflow data

    NASA Astrophysics Data System (ADS)

    Abdulla, F. A.; Lettenmaier, D. P.; Liang, Xu

    1999-09-01

    An approach is described for estimation of baseflow parameters of the ARNO model, using historical baseflow recession sequences extracted from daily streamflow records. This approach allows four of the model parameters to be estimated without rainfall data, and effectively facilitates partitioning of the parameter estimation procedure so that parsimonious search procedures can be used to estimate the remaining storm response parameters separately. Three methods of optimization are evaluated for estimation of four baseflow parameters. These methods are the downhill Simplex (S), Simulated Annealing combined with the Simplex method (SA) and Shuffled Complex Evolution (SCE). These estimation procedures are explored in conjunction with four objective functions: (1) ordinary least squares; (2) ordinary least squares with Box-Cox transformation; (3) ordinary least squares on prewhitened residuals; (4) ordinary least squares applied to prewhitened with Box-Cox transformation of residuals. The effects of changing the seed random generator for both SA and SCE methods are also explored, as are the effects of the bounds of the parameters. Although all schemes converge to the same values of the objective function, SCE method was found to be less sensitive to these issues than both the SA and the Simplex schemes. Parameter uncertainty and interactions are investigated through estimation of the variance-covariance matrix and confidence intervals. As expected the parameters were found to be correlated and the covariance matrix was found to be not diagonal. Furthermore, the linearized confidence interval theory failed for about one-fourth of the catchments while the maximum likelihood theory did not fail for any of the catchments.

  6. Entanglement-Assisted Weak Value Amplification

    NASA Astrophysics Data System (ADS)

    Pang, Shengshi; Dressel, Justin; Brun, Todd A.

    2014-07-01

    Large weak values have been used to amplify the sensitivity of a linear response signal for detecting changes in a small parameter, which has also enabled a simple method for precise parameter estimation. However, producing a large weak value requires a low postselection probability for an ancilla degree of freedom, which limits the utility of the technique. We propose an improvement to this method that uses entanglement to increase the efficiency. We show that by entangling and postselecting n ancillas, the postselection probability can be increased by a factor of n while keeping the weak value fixed (compared to n uncorrelated attempts with one ancilla), which is the optimal scaling with n that is expected from quantum metrology. Furthermore, we show the surprising result that the quantum Fisher information about the detected parameter can be almost entirely preserved in the postselected state, which allows the sensitive estimation to approximately saturate the relevant quantum Cramér-Rao bound. To illustrate this protocol we provide simple quantum circuits that can be implemented using current experimental realizations of three entangled qubits.

  7. Anomaly Monitoring Method for Key Components of Satellite

    PubMed Central

    Fan, Linjun; Xiao, Weidong; Tang, Jun

    2014-01-01

    This paper presented a fault diagnosis method for key components of satellite, called Anomaly Monitoring Method (AMM), which is made up of state estimation based on Multivariate State Estimation Techniques (MSET) and anomaly detection based on Sequential Probability Ratio Test (SPRT). On the basis of analysis failure of lithium-ion batteries (LIBs), we divided the failure of LIBs into internal failure, external failure, and thermal runaway and selected electrolyte resistance (R e) and the charge transfer resistance (R ct) as the key parameters of state estimation. Then, through the actual in-orbit telemetry data of the key parameters of LIBs, we obtained the actual residual value (R X) and healthy residual value (R L) of LIBs based on the state estimation of MSET, and then, through the residual values (R X and R L) of LIBs, we detected the anomaly states based on the anomaly detection of SPRT. Lastly, we conducted an example of AMM for LIBs, and, according to the results of AMM, we validated the feasibility and effectiveness of AMM by comparing it with the results of threshold detective method (TDM). PMID:24587703

  8. Estimation of genetic parameters and response to selection for a continuous trait subject to culling before testing.

    PubMed

    Arnason, T; Albertsdóttir, E; Fikse, W F; Eriksson, S; Sigurdsson, A

    2012-02-01

    The consequences of assuming a zero environmental covariance between a binary trait 'test-status' and a continuous trait on the estimates of genetic parameters by restricted maximum likelihood and Gibbs sampling and on response from genetic selection when the true environmental covariance deviates from zero were studied. Data were simulated for two traits (one that culling was based on and a continuous trait) using the following true parameters, on the underlying scale: h² = 0.4; r(A) = 0.5; r(E) = 0.5, 0.0 or -0.5. The selection on the continuous trait was applied to five subsequent generations where 25 sires and 500 dams produced 1500 offspring per generation. Mass selection was applied in the analysis of the effect on estimation of genetic parameters. Estimated breeding values were used in the study of the effect of genetic selection on response and accuracy. The culling frequency was either 0.5 or 0.8 within each generation. Each of 10 replicates included 7500 records on 'test-status' and 9600 animals in the pedigree file. Results from bivariate analysis showed unbiased estimates of variance components and genetic parameters when true r(E) = 0.0. For r(E) = 0.5, variance components (13-19% bias) and especially (50-80%) were underestimated for the continuous trait, while heritability estimates were unbiased. For r(E) = -0.5, heritability estimates of test-status were unbiased, while genetic variance and heritability of the continuous trait together with were overestimated (25-50%). The bias was larger for the higher culling frequency. Culling always reduced genetic progress from selection, but the genetic progress was found to be robust to the use of wrong parameter values of the true environmental correlation between test-status and the continuous trait. Use of a bivariate linear-linear model reduced bias in genetic evaluations, when data were subject to culling. © 2011 Blackwell Verlag GmbH.

  9. Bayesian generalized least squares regression with application to log Pearson type 3 regional skew estimation

    NASA Astrophysics Data System (ADS)

    Reis, D. S.; Stedinger, J. R.; Martins, E. S.

    2005-10-01

    This paper develops a Bayesian approach to analysis of a generalized least squares (GLS) regression model for regional analyses of hydrologic data. The new approach allows computation of the posterior distributions of the parameters and the model error variance using a quasi-analytic approach. Two regional skew estimation studies illustrate the value of the Bayesian GLS approach for regional statistical analysis of a shape parameter and demonstrate that regional skew models can be relatively precise with effective record lengths in excess of 60 years. With Bayesian GLS the marginal posterior distribution of the model error variance and the corresponding mean and variance of the parameters can be computed directly, thereby providing a simple but important extension of the regional GLS regression procedures popularized by Tasker and Stedinger (1989), which is sensitive to the likely values of the model error variance when it is small relative to the sampling error in the at-site estimator.

  10. Oracle estimation of parametric models under boundary constraints.

    PubMed

    Wong, Kin Yau; Goldberg, Yair; Fine, Jason P

    2016-12-01

    In many classical estimation problems, the parameter space has a boundary. In most cases, the standard asymptotic properties of the estimator do not hold when some of the underlying true parameters lie on the boundary. However, without knowledge of the true parameter values, confidence intervals constructed assuming that the parameters lie in the interior are generally over-conservative. A penalized estimation method is proposed in this article to address this issue. An adaptive lasso procedure is employed to shrink the parameters to the boundary, yielding oracle inference which adapt to whether or not the true parameters are on the boundary. When the true parameters are on the boundary, the inference is equivalent to that which would be achieved with a priori knowledge of the boundary, while if the converse is true, the inference is equivalent to that which is obtained in the interior of the parameter space. The method is demonstrated under two practical scenarios, namely the frailty survival model and linear regression with order-restricted parameters. Simulation studies and real data analyses show that the method performs well with realistic sample sizes and exhibits certain advantages over standard methods. © 2016, The International Biometric Society.

  11. The use of the McIlwain L-parameter to estimate cosmic ray vertical cutoff rigidities for different epochs of the geomagnetic field

    NASA Technical Reports Server (NTRS)

    Shea, M. A.; Smart, D. F.; Gentile, L. C.

    1985-01-01

    Secular changes in the geomagnetic field between 1955 and 1980 have been large enough to produce significant differences in both the verical cutoff rigidities and in the L-value for a specified position. A useful relationship employing the McIlwain L-parameter to estimate vertical cutoff rigidities has been derived for the twenty-five year period.

  12. Advanced image processing approach for ET estimation with remote sensing data of varying spectral, spatial and temporal resolutions

    Treesearch

    Sudhanshu Panda; Devendra Amatya; Young Kim; Ge Sun

    2016-01-01

    Evapotranspiration (ET) is one of the most important hydrologic parameters for vegetation growth, carbon sequestration, and other associated biodiversity study and analysis. Plant stomatal conductance, leaf area index, canopy temperature, soil moisture, and wind speed values generally correlate well with ET. It is difficult to estimate these hydrologic parameters of...

  13. Strategies for Efficient Computation of the Expected Value of Partial Perfect Information

    PubMed Central

    Madan, Jason; Ades, Anthony E.; Price, Malcolm; Maitland, Kathryn; Jemutai, Julie; Revill, Paul; Welton, Nicky J.

    2014-01-01

    Expected value of information methods evaluate the potential health benefits that can be obtained from conducting new research to reduce uncertainty in the parameters of a cost-effectiveness analysis model, hence reducing decision uncertainty. Expected value of partial perfect information (EVPPI) provides an upper limit to the health gains that can be obtained from conducting a new study on a subset of parameters in the cost-effectiveness analysis and can therefore be used as a sensitivity analysis to identify parameters that most contribute to decision uncertainty and to help guide decisions around which types of study are of most value to prioritize for funding. A common general approach is to use nested Monte Carlo simulation to obtain an estimate of EVPPI. This approach is computationally intensive, can lead to significant sampling bias if an inadequate number of inner samples are obtained, and incorrect results can be obtained if correlations between parameters are not dealt with appropriately. In this article, we set out a range of methods for estimating EVPPI that avoid the need for nested simulation: reparameterization of the net benefit function, Taylor series approximations, and restricted cubic spline estimation of conditional expectations. For each method, we set out the generalized functional form that net benefit must take for the method to be valid. By specifying this functional form, our methods are able to focus on components of the model in which approximation is required, avoiding the complexities involved in developing statistical approximations for the model as a whole. Our methods also allow for any correlations that might exist between model parameters. We illustrate the methods using an example of fluid resuscitation in African children with severe malaria. PMID:24449434

  14. Optimal time points sampling in pathway modelling.

    PubMed

    Hu, Shiyan

    2004-01-01

    Modelling cellular dynamics based on experimental data is at the heart of system biology. Considerable progress has been made to dynamic pathway modelling as well as the related parameter estimation. However, few of them gives consideration for the issue of optimal sampling time selection for parameter estimation. Time course experiments in molecular biology rarely produce large and accurate data sets and the experiments involved are usually time consuming and expensive. Therefore, to approximate parameters for models with only few available sampling data is of significant practical value. For signal transduction, the sampling intervals are usually not evenly distributed and are based on heuristics. In the paper, we investigate an approach to guide the process of selecting time points in an optimal way to minimize the variance of parameter estimates. In the method, we first formulate the problem to a nonlinear constrained optimization problem by maximum likelihood estimation. We then modify and apply a quantum-inspired evolutionary algorithm, which combines the advantages of both quantum computing and evolutionary computing, to solve the optimization problem. The new algorithm does not suffer from the morass of selecting good initial values and being stuck into local optimum as usually accompanied with the conventional numerical optimization techniques. The simulation results indicate the soundness of the new method.

  15. Effects of correcting missing daily feed intake values on the genetic parameters and estimated breeding values for feeding traits in pigs.

    PubMed

    Ito, Tetsuya; Fukawa, Kazuo; Kamikawa, Mai; Nikaidou, Satoshi; Taniguchi, Masaaki; Arakawa, Aisaku; Tanaka, Genki; Mikawa, Satoshi; Furukawa, Tsutomu; Hirose, Kensuke

    2018-01-01

    Daily feed intake (DFI) is an important consideration for improving feed efficiency, but measurements using electronic feeder systems contain many missing and incorrect values. Therefore, we evaluated three methods for correcting missing DFI data (quadratic, orthogonal polynomial, and locally weighted (Loess) regression equations) and assessed the effects of these missing values on the genetic parameters and the estimated breeding values (EBV) for feeding traits. DFI records were obtained from 1622 Duroc pigs, comprising 902 individuals without missing DFI and 720 individuals with missing DFI. The Loess equation was the most suitable method for correcting the missing DFI values in 5-50% randomly deleted datasets among the three equations. Both variance components and heritability for the average DFI (ADFI) did not change because of the missing DFI proportion and Loess correction. In terms of rank correlation and information criteria, Loess correction improved the accuracy of EBV for ADFI compared to randomly deleted cases. These findings indicate that the Loess equation is useful for correcting missing DFI values for individual pigs and that the correction of missing DFI values could be effective for the estimation of breeding values and genetic improvement using EBV for feeding traits. © 2017 The Authors. Animal Science Journal published by John Wiley & Sons Australia, Ltd on behalf of Japanese Society of Animal Science.

  16. A statistical methodology for estimating transport parameters: Theory and applications to one-dimensional advectivec-dispersive systems

    USGS Publications Warehouse

    Wagner, Brian J.; Gorelick, Steven M.

    1986-01-01

    A simulation nonlinear multiple-regression methodology for estimating parameters that characterize the transport of contaminants is developed and demonstrated. Finite difference contaminant transport simulation is combined with a nonlinear weighted least squares multiple-regression procedure. The technique provides optimal parameter estimates and gives statistics for assessing the reliability of these estimates under certain general assumptions about the distributions of the random measurement errors. Monte Carlo analysis is used to estimate parameter reliability for a hypothetical homogeneous soil column for which concentration data contain large random measurement errors. The value of data collected spatially versus data collected temporally was investigated for estimation of velocity, dispersion coefficient, effective porosity, first-order decay rate, and zero-order production. The use of spatial data gave estimates that were 2–3 times more reliable than estimates based on temporal data for all parameters except velocity. Comparison of estimated linear and nonlinear confidence intervals based upon Monte Carlo analysis showed that the linear approximation is poor for dispersion coefficient and zero-order production coefficient when data are collected over time. In addition, examples demonstrate transport parameter estimation for two real one-dimensional systems. First, the longitudinal dispersivity and effective porosity of an unsaturated soil are estimated using laboratory column data. We compare the reliability of estimates based upon data from individual laboratory experiments versus estimates based upon pooled data from several experiments. Second, the simulation nonlinear regression procedure is extended to include an additional governing equation that describes delayed storage during contaminant transport. The model is applied to analyze the trends, variability, and interrelationship of parameters in a mourtain stream in northern California.

  17. The Inverse Problem for Confined Aquifer Flow: Identification and Estimation With Extensions

    NASA Astrophysics Data System (ADS)

    Loaiciga, Hugo A.; MariñO, Miguel A.

    1987-01-01

    The contributions of this work are twofold. First, a methodology for estimating the elements of parameter matrices in the governing equation of flow in a confined aquifer is developed. The estimation techniques for the distributed-parameter inverse problem pertain to linear least squares and generalized least squares methods. The linear relationship among the known heads and unknown parameters of the flow equation provides the background for developing criteria for determining the identifiability status of unknown parameters. Under conditions of exact or overidentification it is possible to develop statistically consistent parameter estimators and their asymptotic distributions. The estimation techniques, namely, two-stage least squares and three stage least squares, are applied to a specific groundwater inverse problem and compared between themselves and with an ordinary least squares estimator. The three-stage estimator provides the closer approximation to the actual parameter values, but it also shows relatively large standard errors as compared to the ordinary and two-stage estimators. The estimation techniques provide the parameter matrices required to simulate the unsteady groundwater flow equation. Second, a nonlinear maximum likelihood estimation approach to the inverse problem is presented. The statistical properties of maximum likelihood estimators are derived, and a procedure to construct confidence intervals and do hypothesis testing is given. The relative merits of the linear and maximum likelihood estimators are analyzed. Other topics relevant to the identification and estimation methodologies, i.e., a continuous-time solution to the flow equation, coping with noise-corrupted head measurements, and extension of the developed theory to nonlinear cases are also discussed. A simulation study is used to evaluate the methods developed in this study.

  18. Diffusion parameter mapping with the combined intravoxel incoherent motion and kurtosis model using artificial neural networks at 3 T.

    PubMed

    Bertleff, Marco; Domsch, Sebastian; Weingärtner, Sebastian; Zapp, Jascha; O'Brien, Kieran; Barth, Markus; Schad, Lothar R

    2017-12-01

    Artificial neural networks (ANNs) were used for voxel-wise parameter estimation with the combined intravoxel incoherent motion (IVIM) and kurtosis model facilitating robust diffusion parameter mapping in the human brain. The proposed ANN approach was compared with conventional least-squares regression (LSR) and state-of-the-art multi-step fitting (LSR-MS) in Monte-Carlo simulations and in vivo in terms of estimation accuracy and precision, number of outliers and sensitivity in the distinction between grey (GM) and white (WM) matter. Both the proposed ANN approach and LSR-MS yielded visually increased parameter map quality. Estimations of all parameters (perfusion fraction f, diffusion coefficient D, pseudo-diffusion coefficient D*, kurtosis K) were in good agreement with the literature using ANN, whereas LSR-MS resulted in D* overestimation and LSR yielded increased values for f and D*, as well as decreased values for K. Using ANN, outliers were reduced for the parameters f (ANN, 1%; LSR-MS, 19%; LSR, 8%), D* (ANN, 21%; LSR-MS, 25%; LSR, 23%) and K (ANN, 0%; LSR-MS, 0%; LSR, 15%). Moreover, ANN enabled significant distinction between GM and WM based on all parameters, whereas LSR facilitated this distinction only based on D and LSR-MS on f, D and K. Overall, the proposed ANN approach was found to be superior to conventional LSR, posing a powerful alternative to the state-of-the-art method LSR-MS with several advantages in the estimation of IVIM-kurtosis parameters, which might facilitate increased applicability of enhanced diffusion models at clinical scan times. Copyright © 2017 John Wiley & Sons, Ltd.

  19. Bayesian inference for psychology, part IV: parameter estimation and Bayes factors.

    PubMed

    Rouder, Jeffrey N; Haaf, Julia M; Vandekerckhove, Joachim

    2018-02-01

    In the psychological literature, there are two seemingly different approaches to inference: that from estimation of posterior intervals and that from Bayes factors. We provide an overview of each method and show that a salient difference is the choice of models. The two approaches as commonly practiced can be unified with a certain model specification, now popular in the statistics literature, called spike-and-slab priors. A spike-and-slab prior is a mixture of a null model, the spike, with an effect model, the slab. The estimate of the effect size here is a function of the Bayes factor, showing that estimation and model comparison can be unified. The salient difference is that common Bayes factor approaches provide for privileged consideration of theoretically useful parameter values, such as the value corresponding to the null hypothesis, while estimation approaches do not. Both approaches, either privileging the null or not, are useful depending on the goals of the analyst.

  20. Lake Number, a quantitative indicator of mixing used to estimate changes in dissolved oxygen

    USGS Publications Warehouse

    Robertson, Dale M.; Imberger, Jorg

    1994-01-01

    Lake Number, LN, values are shown to be quantitative indicators of deep mixing in lakes and reservoirs that can be used to estimate changes in deep water dissolved oxygen (DO) concentrations. LN is a dimensionless parameter defined as the ratio of the moments about the center of volume of the water body, of the stabilizing force of gravity associated with density stratification to the destabilizing forces supplied by wind, cooling, inflow, outflow, and other artificial mixing devices. To demonstrate the universality of this parameter, LN values are used to describe the extent of deep mixing and are compared with changes in DO concentrations in three reservoirs in Australia and four lakes in the U.S.A., which vary in productivity and mixing regimes. A simple model is developed which relates changes in LN values, i.e., the extent of mixing, to changes in near bottom DO concentrations. After calibrating the model for a specific system, it is possible to use real-time LN values, calculated using water temperature profiles and surface wind velocities, to estimate changes in DO concentrations (assuming unchanged trophic conditions).

  1. Modeling spatially-varying landscape change points in species occurrence thresholds

    USGS Publications Warehouse

    Wagner, Tyler; Midway, Stephen R.

    2014-01-01

    Predicting species distributions at scales of regions to continents is often necessary, as large-scale phenomena influence the distributions of spatially structured populations. Land use and land cover are important large-scale drivers of species distributions, and landscapes are known to create species occurrence thresholds, where small changes in a landscape characteristic results in abrupt changes in occurrence. The value of the landscape characteristic at which this change occurs is referred to as a change point. We present a hierarchical Bayesian threshold model (HBTM) that allows for estimating spatially varying parameters, including change points. Our model also allows for modeling estimated parameters in an effort to understand large-scale drivers of variability in land use and land cover on species occurrence thresholds. We use range-wide detection/nondetection data for the eastern brook trout (Salvelinus fontinalis), a stream-dwelling salmonid, to illustrate our HBTM for estimating and modeling spatially varying threshold parameters in species occurrence. We parameterized the model for investigating thresholds in landscape predictor variables that are measured as proportions, and which are therefore restricted to values between 0 and 1. Our HBTM estimated spatially varying thresholds in brook trout occurrence for both the proportion agricultural and urban land uses. There was relatively little spatial variation in change point estimates, although there was spatial variability in the overall shape of the threshold response and associated uncertainty. In addition, regional mean stream water temperature was correlated to the change point parameters for the proportion of urban land use, with the change point value increasing with increasing mean stream water temperature. We present a framework for quantify macrosystem variability in spatially varying threshold model parameters in relation to important large-scale drivers such as land use and land cover. Although the model presented is a logistic HBTM, it can easily be extended to accommodate other statistical distributions for modeling species richness or abundance.

  2. Dynamic control of remelting processes

    DOEpatents

    Bertram, Lee A.; Williamson, Rodney L.; Melgaard, David K.; Beaman, Joseph J.; Evans, David G.

    2000-01-01

    An apparatus and method of controlling a remelting process by providing measured process variable values to a process controller; estimating process variable values using a process model of a remelting process; and outputting estimated process variable values from the process controller. Feedback and feedforward control devices receive the estimated process variable values and adjust inputs to the remelting process. Electrode weight, electrode mass, electrode gap, process current, process voltage, electrode position, electrode temperature, electrode thermal boundary layer thickness, electrode velocity, electrode acceleration, slag temperature, melting efficiency, cooling water temperature, cooling water flow rate, crucible temperature profile, slag skin temperature, and/or drip short events are employed, as are parameters representing physical constraints of electroslag remelting or vacuum arc remelting, as applicable.

  3. Sensorless FOC Performance Improved with On-Line Speed and Rotor Resistance Estimator Based on an Artificial Neural Network for an Induction Motor Drive

    PubMed Central

    Gutierrez-Villalobos, Jose M.; Rodriguez-Resendiz, Juvenal; Rivas-Araiza, Edgar A.; Martínez-Hernández, Moisés A.

    2015-01-01

    Three-phase induction motor drive requires high accuracy in high performance processes in industrial applications. Field oriented control, which is one of the most employed control schemes for induction motors, bases its function on the electrical parameter estimation coming from the motor. These parameters make an electrical machine driver work improperly, since these electrical parameter values change at low speeds, temperature changes, and especially with load and duty changes. The focus of this paper is the real-time and on-line electrical parameters with a CMAC-ADALINE block added in the standard FOC scheme to improve the IM driver performance and endure the driver and the induction motor lifetime. Two kinds of neural network structures are used; one to estimate rotor speed and the other one to estimate rotor resistance of an induction motor. PMID:26131677

  4. Nonlinear Quantum Metrology of Many-Body Open Systems

    NASA Astrophysics Data System (ADS)

    Beau, M.; del Campo, A.

    2017-07-01

    We introduce general bounds for the parameter estimation error in nonlinear quantum metrology of many-body open systems in the Markovian limit. Given a k -body Hamiltonian and p -body Lindblad operators, the estimation error of a Hamiltonian parameter using a Greenberger-Horne-Zeilinger state as a probe is shown to scale as N-[k -(p /2 )], surpassing the shot-noise limit for 2 k >p +1 . Metrology equivalence between initial product states and maximally entangled states is established for p ≥1 . We further show that one can estimate the system-environment coupling parameter with precision N-(p /2 ), while many-body decoherence enhances the precision to N-k in the noise-amplitude estimation of a fluctuating k -body Hamiltonian. For the long-range Ising model, we show that the precision of this parameter beats the shot-noise limit when the range of interactions is below a threshold value.

  5. Sensorless FOC Performance Improved with On-Line Speed and Rotor Resistance Estimator Based on an Artificial Neural Network for an Induction Motor Drive.

    PubMed

    Gutierrez-Villalobos, Jose M; Rodriguez-Resendiz, Juvenal; Rivas-Araiza, Edgar A; Martínez-Hernández, Moisés A

    2015-06-29

    Three-phase induction motor drive requires high accuracy in high performance processes in industrial applications. Field oriented control, which is one of the most employed control schemes for induction motors, bases its function on the electrical parameter estimation coming from the motor. These parameters make an electrical machine driver work improperly, since these electrical parameter values change at low speeds, temperature changes, and especially with load and duty changes. The focus of this paper is the real-time and on-line electrical parameters with a CMAC-ADALINE block added in the standard FOC scheme to improve the IM driver performance and endure the driver and the induction motor lifetime. Two kinds of neural network structures are used; one to estimate rotor speed and the other one to estimate rotor resistance of an induction motor.

  6. Robust estimation of thermodynamic parameters (ΔH, ΔS and ΔCp) for prediction of retention time in gas chromatography - Part II (Application).

    PubMed

    Claumann, Carlos Alberto; Wüst Zibetti, André; Bolzan, Ariovaldo; Machado, Ricardo A F; Pinto, Leonel Teixeira

    2015-12-18

    For this work, an analysis of parameter estimation for the retention factor in GC model was performed, considering two different criteria: sum of square error, and maximum error in absolute value; relevant statistics are described for each case. The main contribution of this work is the implementation of an initialization scheme (specialized) for the estimated parameters, which features fast convergence (low computational time) and is based on knowledge of the surface of the error criterion. In an application to a series of alkanes, specialized initialization resulted in significant reduction to the number of evaluations of the objective function (reducing computational time) in the parameter estimation. The obtained reduction happened between one and two orders of magnitude, compared with the simple random initialization. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Parameter estimation techniques based on optimizing goodness-of-fit statistics for structural reliability

    NASA Technical Reports Server (NTRS)

    Starlinger, Alois; Duffy, Stephen F.; Palko, Joseph L.

    1993-01-01

    New methods are presented that utilize the optimization of goodness-of-fit statistics in order to estimate Weibull parameters from failure data. It is assumed that the underlying population is characterized by a three-parameter Weibull distribution. Goodness-of-fit tests are based on the empirical distribution function (EDF). The EDF is a step function, calculated using failure data, and represents an approximation of the cumulative distribution function for the underlying population. Statistics (such as the Kolmogorov-Smirnov statistic and the Anderson-Darling statistic) measure the discrepancy between the EDF and the cumulative distribution function (CDF). These statistics are minimized with respect to the three Weibull parameters. Due to nonlinearities encountered in the minimization process, Powell's numerical optimization procedure is applied to obtain the optimum value of the EDF. Numerical examples show the applicability of these new estimation methods. The results are compared to the estimates obtained with Cooper's nonlinear regression algorithm.

  8. Using dual-domain advective-transport simulation to reconcile multiple-tracer ages and estimate dual-porosity transport parameters

    NASA Astrophysics Data System (ADS)

    Sanford, Ward E.; Niel Plummer, L.; Casile, Gerolamo; Busenberg, Ed; Nelms, David L.; Schlosser, Peter

    2017-06-01

    Dual-domain transport is an alternative conceptual and mathematical paradigm to advection-dispersion for describing the movement of dissolved constituents in groundwater. Here we test the use of a dual-domain algorithm combined with advective pathline tracking to help reconcile environmental tracer concentrations measured in springs within the Shenandoah Valley, USA. The approach also allows for the estimation of the three dual-domain parameters: mobile porosity, immobile porosity, and a domain exchange rate constant. Concentrations of CFC-113, SF6, 3H, and 3He were measured at 28 springs emanating from carbonate rocks. The different tracers give three different mean composite piston-flow ages for all the springs that vary from 5 to 18 years. Here we compare four algorithms that interpret the tracer concentrations in terms of groundwater age: piston flow, old-fraction mixing, advective-flow path modeling, and dual-domain modeling. Whereas the second two algorithms made slight improvements over piston flow at reconciling the disparate piston-flow age estimates, the dual-domain algorithm gave a very marked improvement. Optimal values for the three transport parameters were also obtained, although the immobile porosity value was not well constrained. Parameter correlation and sensitivities were calculated to help quantify the uncertainty. Although some correlation exists between the three parameters being estimated, a watershed simulation of a pollutant breakthrough to a local stream illustrates that the estimated transport parameters can still substantially help to constrain and predict the nature and timing of solute transport. The combined use of multiple environmental tracers with this dual-domain approach could be applicable in a wide variety of fractured-rock settings.

  9. New best estimates for radionuclide solid-liquid distribution coefficients in soils. Part 2: naturally occurring radionuclides.

    PubMed

    Vandenhove, H; Gil-García, C; Rigol, A; Vidal, M

    2009-09-01

    Predicting the transfer of radionuclides in the environment for normal release, accidental, disposal or remediation scenarios in order to assess exposure requires the availability of an important number of generic parameter values. One of the key parameters in environmental assessment is the solid liquid distribution coefficient, K(d), which is used to predict radionuclide-soil interaction and subsequent radionuclide transport in the soil column. This article presents a review of K(d) values for uranium, radium, lead, polonium and thorium based on an extensive literature survey, including recent publications. The K(d) estimates were presented per soil groups defined by their texture and organic matter content (Sand, Loam, Clay and Organic), although the texture class seemed not to significantly affect K(d). Where relevant, other K(d) classification systems are proposed and correlations with soil parameters are highlighted. The K(d) values obtained in this compilation are compared with earlier review data.

  10. Quantitative Diagnosis of Continuous-Valued, Stead-State Systems

    NASA Technical Reports Server (NTRS)

    Rouquette, N.

    1995-01-01

    Quantitative diagnosis involves numerically estimating the values of unobservable parameters that best explain the observed parameter values. We consider quantitative diagnosis for continuous, lumped- parameter, steady-state physical systems because such models are easy to construct and the diagnosis problem is considerably simpler than that for corresponding dynamic models. To further tackle the difficulties of numerically inverting a simulation model to compute a diagnosis, we propose to decompose a physical system model in terms of feedback loops. This decomposition reduces the dimension of the problem and consequently decreases the diagnosis search space. We illustrate this approach on a model of thermal control system studied in earlier research.

  11. Multi-response calibration of a conceptual hydrological model in the semiarid catchment of Wadi al Arab, Jordan

    NASA Astrophysics Data System (ADS)

    Rödiger, T.; Geyer, S.; Mallast, U.; Merz, R.; Krause, P.; Fischer, C.; Siebert, C.

    2014-02-01

    A key factor for sustainable management of groundwater systems is the accurate estimation of groundwater recharge. Hydrological models are common tools for such estimations and widely used. As such models need to be calibrated against measured values, the absence of adequate data can be problematic. We present a nested multi-response calibration approach for a semi-distributed hydrological model in the semi-arid catchment of Wadi al Arab in Jordan, with sparsely available runoff data. The basic idea of the calibration approach is to use diverse observations in a nested strategy, in which sub-parts of the model are calibrated to various observation data types in a consecutive manner. First, the available different data sources have to be screened for information content of processes, e.g. if data sources contain information on mean values, spatial or temporal variability etc. for the entire catchment or only sub-catchments. In a second step, the information content has to be mapped to relevant model components, which represent these processes. Then the data source is used to calibrate the respective subset of model parameters, while the remaining model parameters remain unchanged. This mapping is repeated for other available data sources. In that study the gauged spring discharge (GSD) method, flash flood observations and data from the chloride mass balance (CMB) are used to derive plausible parameter ranges for the conceptual hydrological model J2000g. The water table fluctuation (WTF) method is used to validate the model. Results from modelling using a priori parameter values from literature as a benchmark are compared. The estimated recharge rates of the calibrated model deviate less than ±10% from the estimates derived from WTF method. Larger differences are visible in the years with high uncertainties in rainfall input data. The performance of the calibrated model during validation produces better results than applying the model with only a priori parameter values. The model with a priori parameter values from literature tends to overestimate recharge rates with up to 30%, particular in the wet winter of 1991/1992. An overestimation of groundwater recharge and hence available water resources clearly endangers reliable water resource managing in water scarce region. The proposed nested multi-response approach may help to better predict water resources despite data scarcity.

  12. Simultaneous inversion of multiple land surface parameters from MODIS optical-thermal observations

    NASA Astrophysics Data System (ADS)

    Ma, Han; Liang, Shunlin; Xiao, Zhiqiang; Shi, Hanyu

    2017-06-01

    Land surface parameters from remote sensing observations are critical in monitoring and modeling of global climate change and biogeochemical cycles. Current methods for estimating land surface variables usually focus on individual parameters separately even from the same satellite observations, resulting in inconsistent products. Moreover, no efforts have been made to generate global products from integrated observations from the optical to Thermal InfraRed (TIR) spectrum. Particularly, Middle InfraRed (MIR) observations have received little attention due to the complexity of the radiometric signal, which contains both reflected and emitted radiation. In this paper, we propose a unified algorithm for simultaneously retrieving six land surface parameters - Leaf Area Index (LAI), Fraction of Absorbed Photosynthetically Active Radiation (FAPAR), land surface albedo, Land Surface Emissivity (LSE), Land Surface Temperature (LST), and Upwelling Longwave radiation (LWUP) by exploiting MODIS visible-to-TIR observations. We incorporate a unified physical radiative transfer model into a data assimilation framework. The MODIS visible-to-TIR time series datasets include the daily surface reflectance product and MIR-to-TIR surface radiance, which are atmospherically corrected from the MODIS data using the Moderate Resolution Transmittance program (MODTRAN, ver. 5.0). LAI was first estimated using a data assimilation method that combines MODIS daily reflectance data and a LAI phenology model, and then the LAI was input to the unified radiative transfer model to simulate spectral surface reflectance and surface emissivity for calculating surface broadband albedo and emissivity, and FAPAR. LST was estimated from the MIR-TIR surface radiance data and the simulated emissivity, using an iterative optimization procedure. Lastly, LWUP was estimated using the LST and surface emissivity. The retrieved six parameters were extensively validated across six representative sites with different biome types, and compared with MODIS, GLASS, and GlobAlbedo land surface products. The results demonstrate that the unified inversion algorithm can retrieve temporally complete and physically consistent land surface parameters, and provides more accurate estimates of surface albedo, LST, and LWUP than existing products, with R2 values of 0.93 and 0.62, RMSE of 0.029 and 0.037, and BIAS values of 0.016 and 0.012 for the retrieved and MODIS albedo products, respectively, compared with field albedo measurements; R2 values of 0.95 and 0.93, RMSE of 2.7 and 4.2 K, and BIAS values of -0.6 and -2.7 K for the retrieved and MODIS LST products, respectively, compared with field LST measurements; and R2 values of 0.93 and 0.94, RMSE of 18.2 and 22.8 W/m2, and BIAS values of -2.7 and -14.6 W/m2 for the retrieved and MODIS LWUP products, respectively, compared with field LWUP measurements.

  13. A new parametric method to smooth time-series data of metabolites in metabolic networks.

    PubMed

    Miyawaki, Atsuko; Sriyudthsak, Kansuporn; Hirai, Masami Yokota; Shiraishi, Fumihide

    2016-12-01

    Mathematical modeling of large-scale metabolic networks usually requires smoothing of metabolite time-series data to account for measurement or biological errors. Accordingly, the accuracy of smoothing curves strongly affects the subsequent estimation of model parameters. Here, an efficient parametric method is proposed for smoothing metabolite time-series data, and its performance is evaluated. To simplify parameter estimation, the method uses S-system-type equations with simple power law-type efflux terms. Iterative calculation using this method was found to readily converge, because parameters are estimated stepwise. Importantly, smoothing curves are determined so that metabolite concentrations satisfy mass balances. Furthermore, the slopes of smoothing curves are useful in estimating parameters, because they are probably close to their true behaviors regardless of errors that may be present in the actual data. Finally, calculations for each differential equation were found to converge in much less than one second if initial parameters are set at appropriate (guessed) values. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Inference of reactive transport model parameters using a Bayesian multivariate approach

    NASA Astrophysics Data System (ADS)

    Carniato, Luca; Schoups, Gerrit; van de Giesen, Nick

    2014-08-01

    Parameter estimation of subsurface transport models from multispecies data requires the definition of an objective function that includes different types of measurements. Common approaches are weighted least squares (WLS), where weights are specified a priori for each measurement, and weighted least squares with weight estimation (WLS(we)) where weights are estimated from the data together with the parameters. In this study, we formulate the parameter estimation task as a multivariate Bayesian inference problem. The WLS and WLS(we) methods are special cases in this framework, corresponding to specific prior assumptions about the residual covariance matrix. The Bayesian perspective allows for generalizations to cases where residual correlation is important and for efficient inference by analytically integrating out the variances (weights) and selected covariances from the joint posterior. Specifically, the WLS and WLS(we) methods are compared to a multivariate (MV) approach that accounts for specific residual correlations without the need for explicit estimation of the error parameters. When applied to inference of reactive transport model parameters from column-scale data on dissolved species concentrations, the following results were obtained: (1) accounting for residual correlation between species provides more accurate parameter estimation for high residual correlation levels whereas its influence for predictive uncertainty is negligible, (2) integrating out the (co)variances leads to an efficient estimation of the full joint posterior with a reduced computational effort compared to the WLS(we) method, and (3) in the presence of model structural errors, none of the methods is able to identify the correct parameter values.

  15. Fisher information of a single qubit interacts with a spin-qubit in the presence of a magnetic field

    NASA Astrophysics Data System (ADS)

    Metwally, N.

    2018-06-01

    In this contribution, quantum Fisher information is utilized to estimate the parameters of a central qubit interacting with a single-spin qubit. The effect of the longitudinal, transverse and the rotating strengths of the magnetic field on the estimation degree is discussed. It is shown that, in the resonance case, the number of peaks and consequently the size of the estimation regions increase as the rotating magnetic field strength increases. The precision estimation of the central qubit parameters depends on the initial state settings of the central and the spin-qubit, either encode classical or quantum information. It is displayed that, the upper bounds of the estimation degree are large if the two qubits encode classical information. In the non-resonance case, the estimation degree depends on which of the longitudinal/transverse strength is larger. The coupling constant between the central qubit and the spin-qubit has a different effect on the estimation degree of the weight and the phase parameters, where the possibility of estimating the weight parameter decreases as the coupling constant increases, while it increases for the phase parameter. For large number of spin-particles, namely, we have a spin-bath particles, the upper bounds of the Fisher information with respect to the weight parameter of the central qubit decreases as the number of the spin particle increases. As the interaction time increases, the upper bounds appear at different initial values of the weight parameter.

  16. Multiple robustness in factorized likelihood models.

    PubMed

    Molina, J; Rotnitzky, A; Sued, M; Robins, J M

    2017-09-01

    We consider inference under a nonparametric or semiparametric model with likelihood that factorizes as the product of two or more variation-independent factors. We are interested in a finite-dimensional parameter that depends on only one of the likelihood factors and whose estimation requires the auxiliary estimation of one or several nuisance functions. We investigate general structures conducive to the construction of so-called multiply robust estimating functions, whose computation requires postulating several dimension-reducing models but which have mean zero at the true parameter value provided one of these models is correct.

  17. Parameter estimation and sensitivity analysis for a mathematical model with time delays of leukemia

    NASA Astrophysics Data System (ADS)

    Cândea, Doina; Halanay, Andrei; Rǎdulescu, Rodica; Tǎlmaci, Rodica

    2017-01-01

    We consider a system of nonlinear delay differential equations that describes the interaction between three competing cell populations: healthy, leukemic and anti-leukemia T cells involved in Chronic Myeloid Leukemia (CML) under treatment with Imatinib. The aim of this work is to establish which model parameters are the most important in the success or failure of leukemia remission under treatment using a sensitivity analysis of the model parameters. For the most significant parameters of the model which affect the evolution of CML disease during Imatinib treatment we try to estimate the realistic values using some experimental data. For these parameters, steady states are calculated and their stability is analyzed and biologically interpreted.

  18. Use of algal fluorescence for determination of phytotoxicity of heavy metals and pesticides as environmental pollutants.

    PubMed

    Samson, G; Popovic, R

    1988-12-01

    The phytotoxicity of heavy metals and pesticides was studied by using the fluorescence induction from the alga Dunaliella tertiolecta. The complementary area calculated from the variable fluorescence induction was used as a direct parameter to estimate phytotoxicity. The value of this parameter was affected when algae were treated with different concentrations of mercury, copper, atrazine, DCMU, Dutox, and Soilgard. The toxic effect of these pollutants was estimated by monitoring the decrease in the complementary area, which reflects photosystem II photochemistry. Further, the authors have demonstrated the advantage of using the complementary area as a parameter of phytotoxicity over using variable fluorescence yield. The complementary area of algal fluorescence can be used as a simple and sensitive parameter in the estimation of the phytotoxicity of polluted water.

  19. Theoretical Advances in Sequential Data Assimilation for the Atmosphere and Oceans

    NASA Astrophysics Data System (ADS)

    Ghil, M.

    2007-05-01

    We concentrate here on two aspects of advanced Kalman--filter-related methods: (i) the stability of the forecast- assimilation cycle, and (ii) parameter estimation for the coupled ocean-atmosphere system. The nonlinear stability of a prediction-assimilation system guarantees the uniqueness of the sequentially estimated solutions in the presence of partial and inaccurate observations, distributed in space and time; this stability is shown to be a necessary condition for the convergence of the state estimates to the true evolution of the turbulent flow. The stability properties of the governing nonlinear equations and of several data assimilation systems are studied by computing the spectrum of the associated Lyapunov exponents. These ideas are applied to a simple and an intermediate model of atmospheric variability and we show that the degree of stabilization depends on the type and distribution of the observations, as well as on the data assimilation method. These results represent joint work with A. Carrassi, A. Trevisan and F. Uboldi. Much is known by now about the main physical mechanisms that give rise to and modulate the El-Nino/Southern- Oscillation (ENSO), but the values of several parameters that enter these mechanisms are an important unknown. We apply Extended Kalman Filtering (EKF) for both model state and parameter estimation in an intermediate, nonlinear, coupled ocean-atmosphere model of ENSO. Model behavior is very sensitive to two key parameters: (a) "mu", the ocean-atmosphere coupling coefficient between the sea-surface temperature (SST) and wind stress anomalies; and (b) "delta-s", the surface-layer coefficient. Previous work has shown that "delta- s" determines the period of the model's self-sustained oscillation, while "mu' measures the degree of nonlinearity. Depending on the values of these parameters, the spatio-temporal pattern of model solutions is either that of a delayed oscillator or of a westward propagating mode. Assimilation of SST data from the NCEP- NCAR Reanalysis-2 shows that the parameters can vary on fairly short time scales and switch between values that approximate the two distinct modes of ENSO behavior. Rapid adjustments of these parameters occur, in particular, during strong ENSO events. Ways to apply EKF parameter estimation efficiently to state-of-the-art coupled ocean-atmosphere GCMs will be discussed. These results arise from joint work with D. Kondrashov and C.-j. Sun.

  20. Gravity-darkening exponents in semi-detached binary systems from their photometric observations. II.

    NASA Astrophysics Data System (ADS)

    Djurašević, G.; Rovithis-Livaniou, H.; Rovithis, P.; Georgiades, N.; Erkapić, S.; Pavlović, R.

    2006-01-01

    This second part of our study concerning gravity-darkening presents the results for 8 semi-detached close binary systems. From the light-curve analysis of these systems the exponent of the gravity-darkening (GDE) for the Roche lobe filling components has been empirically derived. The method used for the light-curve analysis is based on Roche geometry, and enables simultaneous estimation of the systems' parameters and the gravity-darkening exponents. Our analysis is restricted to the black-body approximation which can influence in some degree the parameter estimation. The results of our analysis are: 1) For four of the systems, namely: TX UMa, β Per, AW Cam and TW Cas, there is a very good agreement between empirically estimated and theoretically predicted values for purely convective envelopes. 2) For the AI Dra system, the estimated value of gravity-darkening exponent is greater, and for UX Her, TW And and XZ Pup lesser than corresponding theoretical predictions, but for all mentioned systems the obtained values of the gravity-darkening exponent are quite close to the theoretically expected values. 3) Our analysis has proved generally that with the correction of the previously estimated mass ratios of the components within some of the analysed systems, the theoretical predictions of the gravity-darkening exponents for stars with convective envelopes are highly reliable. The anomalous values of the GDE found in some earlier studies of these systems can be considered as the consequence of the inappropriate method used to estimate the GDE. 4) The empirical estimations of GDE given in Paper I and in the present study indicate that in the light-curve analysis one can apply the recent theoretical predictions of GDE with high confidence for stars with both convective and radiative envelopes.

  1. Task-oriented comparison of power spectral density estimation methods for quantifying acoustic attenuation in diagnostic ultrasound using a reference phantom method.

    PubMed

    Rosado-Mendez, Ivan M; Nam, Kibo; Hall, Timothy J; Zagzebski, James A

    2013-07-01

    Reported here is a phantom-based comparison of methods for determining the power spectral density (PSD) of ultrasound backscattered signals. Those power spectral density values are then used to estimate parameters describing α(f), the frequency dependence of the acoustic attenuation coefficient. Phantoms were scanned with a clinical system equipped with a research interface to obtain radiofrequency echo data. Attenuation, modeled as a power law α(f)= α0 f (β), was estimated using a reference phantom method. The power spectral density was estimated using the short-time Fourier transform (STFT), Welch's periodogram, and Thomson's multitaper technique, and performance was analyzed when limiting the size of the parameter-estimation region. Errors were quantified by the bias and standard deviation of the α0 and β estimates, and by the overall power-law fit error (FE). For parameter estimation regions larger than ~34 pulse lengths (~1 cm for this experiment), an overall power-law FE of 4% was achieved with all spectral estimation methods. With smaller parameter estimation regions as in parametric image formation, the bias and standard deviation of the α0 and β estimates depended on the size of the parameter estimation region. Here, the multitaper method reduced the standard deviation of the α0 and β estimates compared with those using the other techniques. The results provide guidance for choosing methods for estimating the power spectral density in quantitative ultrasound methods.

  2. Brain Tissue Compartment Density Estimated Using Diffusion-Weighted MRI Yields Tissue Parameters Consistent With Histology

    PubMed Central

    Sepehrband, Farshid; Clark, Kristi A.; Ullmann, Jeremy F.P.; Kurniawan, Nyoman D.; Leanage, Gayeshika; Reutens, David C.; Yang, Zhengyi

    2015-01-01

    We examined whether quantitative density measures of cerebral tissue consistent with histology can be obtained from diffusion magnetic resonance imaging (MRI). By incorporating prior knowledge of myelin and cell membrane densities, absolute tissue density values were estimated from relative intra-cellular and intra-neurite density values obtained from diffusion MRI. The NODDI (neurite orientation distribution and density imaging) technique, which can be applied clinically, was used. Myelin density estimates were compared with the results of electron and light microscopy in ex vivo mouse brain and with published density estimates in a healthy human brain. In ex vivo mouse brain, estimated myelin densities in different sub-regions of the mouse corpus callosum were almost identical to values obtained from electron microscopy (Diffusion MRI: 42±6%, 36±4% and 43±5%; electron microscopy: 41±10%, 36±8% and 44±12% in genu, body and splenium, respectively). In the human brain, good agreement was observed between estimated fiber density measurements and previously reported values based on electron microscopy. Estimated density values were unaffected by crossing fibers. PMID:26096639

  3. Computer-Based Model Calibration and Uncertainty Analysis: Terms and Concepts

    DTIC Science & Technology

    2015-07-01

    uncertainty analyses throughout the lifecycle of planning, designing, and operating of Civil Works flood risk management projects as described in...value 95% of the time. In the frequentist approach to PE, model parameters area regarded as having true values, and their estimate is based on the...in catchment models. 1. Evaluating parameter uncertainty. Water Resources Research 19(5):1151–1172. Lee, P. M. 2012. Bayesian statistics: An

  4. Application of maximum entropy to statistical inference for inversion of data from a single track segment.

    PubMed

    Stotts, Steven A; Koch, Robert A

    2017-08-01

    In this paper an approach is presented to estimate the constraint required to apply maximum entropy (ME) for statistical inference with underwater acoustic data from a single track segment. Previous algorithms for estimating the ME constraint require multiple source track segments to determine the constraint. The approach is relevant for addressing model mismatch effects, i.e., inaccuracies in parameter values determined from inversions because the propagation model does not account for all acoustic processes that contribute to the measured data. One effect of model mismatch is that the lowest cost inversion solution may be well outside a relatively well-known parameter value's uncertainty interval (prior), e.g., source speed from track reconstruction or towed source levels. The approach requires, for some particular parameter value, the ME constraint to produce an inferred uncertainty interval that encompasses the prior. Motivating this approach is the hypothesis that the proposed constraint determination procedure would produce a posterior probability density that accounts for the effect of model mismatch on inferred values of other inversion parameters for which the priors might be quite broad. Applications to both measured and simulated data are presented for model mismatch that produces minimum cost solutions either inside or outside some priors.

  5. On the robustness of a Bayes estimate. [in reliability theory

    NASA Technical Reports Server (NTRS)

    Canavos, G. C.

    1974-01-01

    This paper examines the robustness of a Bayes estimator with respect to the assigned prior distribution. A Bayesian analysis for a stochastic scale parameter of a Weibull failure model is summarized in which the natural conjugate is assigned as the prior distribution of the random parameter. The sensitivity analysis is carried out by the Monte Carlo method in which, although an inverted gamma is the assigned prior, realizations are generated using distribution functions of varying shape. For several distributional forms and even for some fixed values of the parameter, simulated mean squared errors of Bayes and minimum variance unbiased estimators are determined and compared. Results indicate that the Bayes estimator remains squared-error superior and appears to be largely robust to the form of the assigned prior distribution.

  6. Multiobjective sampling design for parameter estimation and model discrimination in groundwater solute transport

    USGS Publications Warehouse

    Knopman, Debra S.; Voss, Clifford I.

    1989-01-01

    Sampling design for site characterization studies of solute transport in porous media is formulated as a multiobjective problem. Optimal design of a sampling network is a sequential process in which the next phase of sampling is designed on the basis of all available physical knowledge of the system. Three objectives are considered: model discrimination, parameter estimation, and cost minimization. For the first two objectives, physically based measures of the value of information obtained from a set of observations are specified. In model discrimination, value of information of an observation point is measured in terms of the difference in solute concentration predicted by hypothesized models of transport. Points of greatest difference in predictions can contribute the most information to the discriminatory power of a sampling design. Sensitivity of solute concentration to a change in a parameter contributes information on the relative variance of a parameter estimate. Inclusion of points in a sampling design with high sensitivities to parameters tends to reduce variance in parameter estimates. Cost minimization accounts for both the capital cost of well installation and the operating costs of collection and analysis of field samples. Sensitivities, discrimination information, and well installation and sampling costs are used to form coefficients in the multiobjective problem in which the decision variables are binary (zero/one), each corresponding to the selection of an observation point in time and space. The solution to the multiobjective problem is a noninferior set of designs. To gain insight into effective design strategies, a one-dimensional solute transport problem is hypothesized. Then, an approximation of the noninferior set is found by enumerating 120 designs and evaluating objective functions for each of the designs. Trade-offs between pairs of objectives are demonstrated among the models. The value of an objective function for a given design is shown to correspond to the ability of a design to actually meet an objective.

  7. Structure of the Large Magellanic Cloud from near infrared magnitudes of red clump stars

    NASA Astrophysics Data System (ADS)

    Subramanian, S.; Subramaniam, A.

    2013-04-01

    Context. The structural parameters of the disk of the Large Magellanic Cloud (LMC) are estimated. Aims: We used the JH photometric data of red clump (RC) stars from the Magellanic Cloud Point Source Catalog (MCPSC) obtained from the InfraRed Survey Facility (IRSF) to estimate the structural parameters of the LMC disk, such as the inclination, i, and the position angle of the line of nodes (PAlon), φ. Methods: The observed LMC region is divided into several sub-regions, and stars in each region are cross-identified with the optically identified RC stars to obtain the near infrared magnitudes. The peak values of H magnitude and (J - H) colour of the observed RC distribution are obtained by fitting a profile to the distributions and by taking the average value of magnitude and colour of the RC stars in the bin with largest number. Then the dereddened peak H0 magnitude of the RC stars in each sub-region is obtained from the peak values of H magnitude and (J - H) colour of the observed RC distribution. The right ascension (RA), declination (Dec), and relative distance from the centre of each sub-region are converted into x,y, and z Cartesian coordinates. A weighted least square plane fitting method is applied to this x,y,z data to estimate the structural parameters of the LMC disk. Results: An intrinsic (J - H)0 colour of 0.40 ± 0.03 mag in the Simultaneous three-colour InfraRed Imager for Unbiased Survey (SIRIUS) IRSF filter system is estimated for the RC stars in the LMC and a reddening map based on (J - H) colour of the RC stars is presented. When the peaks of the RC distribution were identified by averaging, an inclination of 25°.7 ± 1°.6 and a PAlon = 141°.5 ± 4°.5 were obtained. We estimate a distance modulus, μ = 18.47 ± 0.1 mag to the LMC. Extra-planar features which are both in front and behind the fitted plane are identified. They match with the optically identified extra-planar features. The bar of the LMC is found to be part of the disk within 500 pc. Conclusions: The estimates of the structural parameters are found to be independent of the photometric bands used for the analysis. The radial variation of the structural parameters are also studied. We find that the inner disk, within ~3°.0, is less inclined and has a larger value of PAlon when compared to the outer disk. Our estimates are compared with the literature values, and the possible reasons for the small discrepancies found are discussed.

  8. Evaluation and interpretation of Thematic Mapper ratios in equations for estimating corn growth parameters

    NASA Technical Reports Server (NTRS)

    Dardner, B. R.; Blad, B. L.; Thompson, D. R.; Henderson, K. E.

    1985-01-01

    Reflectance and agronomic Thematic Mapper (TM) data were analyzed to determine possible data transformations for evaluating several plant parameters of corn. Three transformation forms were used: the ratio of two TM bands, logarithms of two-band ratios, and normalized differences of two bands. Normalized differences and logarithms of two-band ratios responsed similarly in the equations for estimating the plant growth parameters evaluated in this study. Two-term equations were required to obtain the maximum predictability of percent ground cover, canopy moisture content, and total wet phytomass. Standard error of estimate values were 15-26 percent lower for two-term estimates of these parameters than for one-term estimates. The terms log(TM4/TM2) and (TM4/TM5) produced the maximum predictability for leaf area and dry green leaf weight, respectively. The middle infrared bands TM5 and TM7 are essential for maximizing predictability for all measured plant parameters except leaf area index. The estimating models were evaluated over bare soil to discriminate between equations which are statistically similar. Qualitative interpretations of the resulting prediction equations are consistent with general agronomic and remote sensing theory.

  9. Nonstationary Extreme Value Analysis in a Changing Climate: A Software Package

    NASA Astrophysics Data System (ADS)

    Cheng, L.; AghaKouchak, A.; Gilleland, E.

    2013-12-01

    Numerous studies show that climatic extremes have increased substantially in the second half of the 20th century. For this reason, analysis of extremes under a nonstationary assumption has received a great deal of attention. This paper presents a software package developed for estimation of return levels, return periods, and risks of climatic extremes in a changing climate. This MATLAB software package offers tools for analysis of climate extremes under both stationary and non-stationary assumptions. The Nonstationary Extreme Value Analysis (hereafter, NEVA) provides an efficient and generalized framework for analyzing extremes using Bayesian inference. NEVA estimates the extreme value parameters using a Differential Evolution Markov Chain (DE-MC) which utilizes the genetic algorithm Differential Evolution (DE) for global optimization over the real parameter space with the Markov Chain Monte Carlo (MCMC) approach and has the advantage of simplicity, speed of calculation and convergence over conventional MCMC. NEVA also offers the confidence interval and uncertainty bounds of estimated return levels based on the sampled parameters. NEVA integrates extreme value design concepts, data analysis tools, optimization and visualization, explicitly designed to facilitate analysis extremes in geosciences. The generalized input and output files of this software package make it attractive for users from across different fields. Both stationary and nonstationary components of the package are validated for a number of case studies using empirical return levels. The results show that NEVA reliably describes extremes and their return levels.

  10. The Rangeland Hydrology and Erosion Model: A Dynamic Approach for Predicting Soil Loss on Rangelands

    NASA Astrophysics Data System (ADS)

    Hernandez, Mariano; Nearing, Mark A.; Al-Hamdan, Osama Z.; Pierson, Frederick B.; Armendariz, Gerardo; Weltz, Mark A.; Spaeth, Kenneth E.; Williams, C. Jason; Nouwakpo, Sayjro K.; Goodrich, David C.; Unkrich, Carl L.; Nichols, Mary H.; Holifield Collins, Chandra D.

    2017-11-01

    In this study, we present the improved Rangeland Hydrology and Erosion Model (RHEM V2.3), a process-based erosion prediction tool specific for rangeland application. The article provides the mathematical formulation of the model and parameter estimation equations. Model performance is assessed against data collected from 23 runoff and sediment events in a shrub-dominated semiarid watershed in Arizona, USA. To evaluate the model, two sets of primary model parameters were determined using the RHEM V2.3 and RHEM V1.0 parameter estimation equations. Testing of the parameters indicated that RHEM V2.3 parameter estimation equations provided a 76% improvement over RHEM V1.0 parameter estimation equations. Second, the RHEM V2.3 model was calibrated to measurements from the watershed. The parameters estimated by the new equations were within the lowest and highest values of the calibrated parameter set. These results suggest that the new parameter estimation equations can be applied for this environment to predict sediment yield at the hillslope scale. Furthermore, we also applied the RHEM V2.3 to demonstrate the response of the model as a function of foliar cover and ground cover for 124 data points across Arizona and New Mexico. The dependence of average sediment yield on surface ground cover was moderately stronger than that on foliar cover. These results demonstrate that RHEM V2.3 predicts runoff volume, peak runoff, and sediment yield with sufficient accuracy for broad application to assess and manage rangeland systems.

  11. Application of Markov chain Monte Carlo analysis to biomathematical modeling of respirable dust in US and UK coal miners

    PubMed Central

    Sweeney, Lisa M.; Parker, Ann; Haber, Lynne T.; Tran, C. Lang; Kuempel, Eileen D.

    2015-01-01

    A biomathematical model was previously developed to describe the long-term clearance and retention of particles in the lungs of coal miners. The model structure was evaluated and parameters were estimated in two data sets, one from the United States and one from the United Kingdom. The three-compartment model structure consists of deposition of inhaled particles in the alveolar region, competing processes of either clearance from the alveolar region or translocation to the lung interstitial region, and very slow, irreversible sequestration of interstitialized material in the lung-associated lymph nodes. Point estimates of model parameter values were estimated separately for the two data sets. In the current effort, Bayesian population analysis using Markov chain Monte Carlo simulation was used to recalibrate the model while improving assessments of parameter variability and uncertainty. When model parameters were calibrated simultaneously to the two data sets, agreement between the derived parameters for the two groups was very good, and the central tendency values were similar to those derived from the deterministic approach. These findings are relevant to the proposed update of the ICRP human respiratory tract model with revisions to the alveolar-interstitial region based on this long-term particle clearance and retention model. PMID:23454101

  12. Automatic estimation of elasticity parameters in breast tissue

    NASA Astrophysics Data System (ADS)

    Skerl, Katrin; Cochran, Sandy; Evans, Andrew

    2014-03-01

    Shear wave elastography (SWE), a novel ultrasound imaging technique, can provide unique information about cancerous tissue. To estimate elasticity parameters, a region of interest (ROI) is manually positioned over the stiffest part of the shear wave image (SWI). The aim of this work is to estimate the elasticity parameters i.e. mean elasticity, maximal elasticity and standard deviation, fully automatically. Ultrasonic SWI of a breast elastography phantom and breast tissue in vivo were acquired using the Aixplorer system (SuperSonic Imagine, Aix-en-Provence, France). First, the SWI within the ultrasonic B-mode image was detected using MATLAB then the elasticity values were extracted. The ROI was automatically positioned over the stiffest part of the SWI and the elasticity parameters were calculated. Finally all values were saved in a spreadsheet which also contains the patient's study ID. This spreadsheet is easily available for physicians and clinical staff for further evaluation and so increase efficiency. Therewith the efficiency is increased. This algorithm simplifies the handling, especially for the performance and evaluation of clinical trials. The SWE processing method allows physicians easy access to the elasticity parameters of the examinations from their own and other institutions. This reduces clinical time and effort and simplifies evaluation of data in clinical trials. Furthermore, reproducibility will be improved.

  13. 40 CFR 98.255 - Procedures for estimating missing data.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... during unit operation or if a required fuel sample is not taken), a substitute data value for the missing...

  14. 40 CFR 98.315 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... estimating missing data. For the petroleum coke input procedure in § 98.313(b), a complete record of all... substitute data value for the missing parameter shall be used in the calculations as specified in the...

  15. 40 CFR 98.295 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... estimating missing data. For the emission calculation methodologies in § 98.293(b)(2) and (b)(3), a complete... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  16. 40 CFR 98.255 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... during unit operation or if a required fuel sample is not taken), a substitute data value for the missing...

  17. 40 CFR 98.255 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... during unit operation or if a required fuel sample is not taken), a substitute data value for the missing...

  18. 40 CFR 98.315 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... estimating missing data. For the petroleum coke input procedure in § 98.313(b), a complete record of all... substitute data value for the missing parameter shall be used in the calculations as specified in the...

  19. 40 CFR 98.315 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... estimating missing data. For the petroleum coke input procedure in § 98.313(b), a complete record of all... substitute data value for the missing parameter shall be used in the calculations as specified in the...

  20. 40 CFR 98.315 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... estimating missing data. For the petroleum coke input procedure in § 98.313(b), a complete record of all... substitute data value for the missing parameter shall be used in the calculations as specified in the...

  1. 40 CFR 98.295 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... estimating missing data. For the emission calculation methodologies in § 98.293(b)(2) and (b)(3), a complete... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  2. 40 CFR 98.255 - Procedures for estimating missing data.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... during unit operation or if a required fuel sample is not taken), a substitute data value for the missing...

  3. 40 CFR 98.195 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... estimating missing data. For the procedure in § 98.193(b)(1), a complete record of all measured parameters... all available process data or data used for accounting purposes. (b) For missing values related to the...

  4. 40 CFR 98.295 - Procedures for estimating missing data.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 21 2011-07-01 2011-07-01 false Procedures for estimating missing data... estimating missing data. For the emission calculation methodologies in § 98.293(b)(2) and (b)(3), a complete... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  5. 40 CFR 98.295 - Procedures for estimating missing data.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Procedures for estimating missing data... estimating missing data. For the emission calculation methodologies in § 98.293(b)(2) and (b)(3), a complete... unavailable, a substitute data value for the missing parameter shall be used in the calculations as specified...

  6. 40 CFR 98.255 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... estimating missing data. A complete record of all measured parameters used in the GHG emissions calculations... during unit operation or if a required fuel sample is not taken), a substitute data value for the missing...

  7. A Monte Carlo Evaluation of Estimated Parameters of Five Shrinkage Estimate Formuli.

    ERIC Educational Resources Information Center

    Newman, Isadore; And Others

    1979-01-01

    A Monte Carlo simulation was employed to determine the accuracy with which the shrinkage in R squared can be estimated by five different shrinkage formulas. The study dealt with the use of shrinkage formulas for various sample sizes, different R squared values, and different degrees of multicollinearity. (Author/JKS)

  8. Linear solvation energy relationships (LSER): 'rules of thumb' for Vi/100, π*, Βm, and αm estimation and use in aquatic toxicology

    USGS Publications Warehouse

    Hickey, James P.

    1996-01-01

    This chapter provides a listing of the increasing variety of organic moieties and heteroatom group for which Linear Solvation Energy Relationship (LSER) values are available, and the LSER variable estimation rules. The listings include values for typical nitrogen-, sulfur- and phosphorus-containing moieties, and general organosilicon and organotin groups. The contributions by an ion pair situation to the LSER values are also offered in Table 1, allowing estimation of parameters for salts and zwitterions. The guidelines permit quick estimation of values for the four primary LSER variables Vi/100, π*, Βm, and αm by summing the contribtuions from its components. The use of guidelines and Table 1 significantly simplifies computation of values for the LSER variables for most possible organic comppounds in the environment, including the larger compounds of environmental and biological interest.

  9. Experimental and computational correlation of fracture parameters KIc, JIc, and GIc for unimodular and bimodular graphite components

    NASA Astrophysics Data System (ADS)

    Bhushan, Awani; Panda, S. K.

    2018-05-01

    The influence of bimodularity (different stress ∼ strain behaviour in tension and compression) on fracture behaviour of graphite specimens has been studied with fracture toughness (KIc), critical J-integral (JIc) and critical strain energy release rate (GIc) as the characterizing parameter. Bimodularity index (ratio of tensile Young's modulus to compression Young's modulus) of graphite specimens has been obtained from the normalized test data of tensile and compression experimentation. Single edge notch bend (SENB) testing of pre-cracked specimens from the same lot have been carried out as per ASTM standard D7779-11 to determine the peak load and critical fracture parameters KIc, GIc and JIc using digital image correlation technology of crack opening displacements. Weibull weakest link theory has been used to evaluate the mean peak load, Weibull modulus and goodness of fit employing two parameter least square method (LIN2), biased (MLE2-B) and unbiased (MLE2-U) maximum likelihood estimator. The stress dependent elasticity problem of three-dimensional crack progression behaviour for the bimodular graphite components has been solved as an iterative finite element procedure. The crack characterizing parameters critical stress intensity factor and critical strain energy release rate have been estimated with the help of Weibull distribution plot between peak loads versus cumulative probability of failure. Experimental and Computational fracture parameters have been compared qualitatively to describe the significance of bimodularity. The bimodular influence on fracture behaviour of SENB graphite has been reflected on the experimental evaluation of GIc values only, which has been found to be different from the calculated JIc values. Numerical evaluation of bimodular 3D J-integral value is found to be close to the GIc value whereas the unimodular 3D J-value is nearer to the JIc value. The significant difference between the unimodular JIc and bimodular GIc indicates that GIc should be considered as the standard fracture parameter for bimodular brittle specimens.

  10. High Throughput pharmacokinetic modeling using computationally predicted parameter values: dissociation constants (TDS)

    EPA Science Inventory

    Estimates of the ionization association and dissociation constant (pKa) are vital to modeling the pharmacokinetic behavior of chemicals in vivo. Methodologies for the prediction of compound sequestration in specific tissues using partition coefficients require a parameter that ch...

  11. Parameter identification for nonlinear aerodynamic systems

    NASA Technical Reports Server (NTRS)

    Pearson, Allan E.

    1990-01-01

    Parameter identification for nonlinear aerodynamic systems is examined. It is presumed that the underlying model can be arranged into an input/output (I/O) differential operator equation of a generic form. The algorithm estimation is especially efficient since the equation error can be integrated exactly given any I/O pair to obtain an algebraic function of the parameters. The algorithm for parameter identification was extended to the order determination problem for linear differential system. The degeneracy in a least squares estimate caused by feedback was addressed. A method of frequency analysis for determining the transfer function G(j omega) from transient I/O data was formulated using complex valued Fourier based modulating functions in contrast with the trigonometric modulating functions for the parameter estimation problem. A simulation result of applying the algorithm is given under noise-free conditions for a system with a low pass transfer function.

  12. Exchangeability, extreme returns and Value-at-Risk forecasts

    NASA Astrophysics Data System (ADS)

    Huang, Chun-Kai; North, Delia; Zewotir, Temesgen

    2017-07-01

    In this paper, we propose a new approach to extreme value modelling for the forecasting of Value-at-Risk (VaR). In particular, the block maxima and the peaks-over-threshold methods are generalised to exchangeable random sequences. This caters for the dependencies, such as serial autocorrelation, of financial returns observed empirically. In addition, this approach allows for parameter variations within each VaR estimation window. Empirical prior distributions of the extreme value parameters are attained by using resampling procedures. We compare the results of our VaR forecasts to that of the unconditional extreme value theory (EVT) approach and the conditional GARCH-EVT model for robust conclusions.

  13. Convergence in parameters and predictions using computational experimental design.

    PubMed

    Hagen, David R; White, Jacob K; Tidor, Bruce

    2013-08-06

    Typically, biological models fitted to experimental data suffer from significant parameter uncertainty, which can lead to inaccurate or uncertain predictions. One school of thought holds that accurate estimation of the true parameters of a biological system is inherently problematic. Recent work, however, suggests that optimal experimental design techniques can select sets of experiments whose members probe complementary aspects of a biochemical network that together can account for its full behaviour. Here, we implemented an experimental design approach for selecting sets of experiments that constrain parameter uncertainty. We demonstrated with a model of the epidermal growth factor-nerve growth factor pathway that, after synthetically performing a handful of optimal experiments, the uncertainty in all 48 parameters converged below 10 per cent. Furthermore, the fitted parameters converged to their true values with a small error consistent with the residual uncertainty. When untested experimental conditions were simulated with the fitted models, the predicted species concentrations converged to their true values with errors that were consistent with the residual uncertainty. This paper suggests that accurate parameter estimation is achievable with complementary experiments specifically designed for the task, and that the resulting parametrized models are capable of accurate predictions.

  14. Weak value amplification considered harmful

    NASA Astrophysics Data System (ADS)

    Ferrie, Christopher; Combes, Joshua

    2014-03-01

    We show using statistically rigorous arguments that the technique of weak value amplification does not perform better than standard statistical techniques for the tasks of parameter estimation and signal detection. We show that using all data and considering the joint distribution of all measurement outcomes yields the optimal estimator. Moreover, we show estimation using the maximum likelihood technique with weak values as small as possible produces better performance for quantum metrology. In doing so, we identify the optimal experimental arrangement to be the one which reveals the maximal eigenvalue of the square of system observables. We also show these conclusions do not change in the presence of technical noise.

  15. Estimation of dynamic rotor loads for the rotor systems research aircraft: Methodology development and validation

    NASA Technical Reports Server (NTRS)

    Duval, R. W.; Bahrami, M.

    1985-01-01

    The Rotor Systems Research Aircraft uses load cells to isolate the rotor/transmission systm from the fuselage. A mathematical model relating applied rotor loads and inertial loads of the rotor/transmission system to the load cell response is required to allow the load cells to be used to estimate rotor loads from flight data. Such a model is derived analytically by applying a force and moment balance to the isolated rotor/transmission system. The model is tested by comparing its estimated values of applied rotor loads with measured values obtained from a ground based shake test. Discrepancies in the comparison are used to isolate sources of unmodeled external loads. Once the structure of the mathematical model has been validated by comparison with experimental data, the parameters must be identified. Since the parameters may vary with flight condition it is desirable to identify the parameters directly from the flight data. A Maximum Likelihood identification algorithm is derived for this purpose and tested using a computer simulation of load cell data. The identification is found to converge within 10 samples. The rapid convergence facilitates tracking of time varying parameters of the load cell model in flight.

  16. Improvement of Parameter Estimations in Tumor Growth Inhibition Models on Xenografted Animals: Handling Sacrifice Censoring and Error Caused by Experimental Measurement on Larger Tumor Sizes.

    PubMed

    Pierrillas, Philippe B; Tod, Michel; Amiel, Magali; Chenel, Marylore; Henin, Emilie

    2016-09-01

    The purpose of this study was to explore the impact of censoring due to animal sacrifice on parameter estimates and tumor volume calculated from two diameters in larger tumors during tumor growth experiments in preclinical studies. The type of measurement error that can be expected was also investigated. Different scenarios were challenged using the stochastic simulation and estimation process. One thousand datasets were simulated under the design of a typical tumor growth study in xenografted mice, and then, eight approaches were used for parameter estimation with the simulated datasets. The distribution of estimates and simulation-based diagnostics were computed for comparison. The different approaches were robust regarding the choice of residual error and gave equivalent results. However, by not considering missing data induced by sacrificing the animal, parameter estimates were biased and led to false inferences in terms of compound potency; the threshold concentration for tumor eradication when ignoring censoring was 581 ng.ml(-1), but the true value was 240 ng.ml(-1).

  17. The Utility of Selection for Military and Civilian Jobs

    DTIC Science & Technology

    1989-07-01

    parsimonious use of information; the relative ease in making threshold (break-even) judgments compared to estimating actual SDy values higher than a... threshold value, even though judges are unlikely to agree on the exact point estimate for the SDy parameter; and greater understanding of how even small...ability, spatial ability, introversion , anxiety) considered to vary or differ across individuals. A construct (sometimes called a latent variable) is not

  18. Estimation of Enthalpy of Formation of Liquid Transition Metal Alloys: A Modified Prescription Based on Macroscopic Atom Model of Cohesion

    NASA Astrophysics Data System (ADS)

    Raju, Subramanian; Saibaba, Saroja

    2016-09-01

    The enthalpy of formation Δo H f is an important thermodynamic quantity, which sheds significant light on fundamental cohesive and structural characteristics of an alloy. However, being a difficult one to determine accurately through experiments, simple estimation procedures are often desirable. In the present study, a modified prescription for estimating Δo H f L of liquid transition metal alloys is outlined, based on the Macroscopic Atom Model of cohesion. This prescription relies on self-consistent estimation of liquid-specific model parameters, namely electronegativity ( ϕ L) and bonding electron density ( n b L ). Such unique identification is made through the use of well-established relationships connecting surface tension, compressibility, and molar volume of a metallic liquid with bonding charge density. The electronegativity is obtained through a consistent linear scaling procedure. The preliminary set of values for ϕ L and n b L , together with other auxiliary model parameters, is subsequently optimized to obtain a good numerical agreement between calculated and experimental values of Δo H f L for sixty liquid transition metal alloys. It is found that, with few exceptions, the use of liquid-specific model parameters in Macroscopic Atom Model yields a physically consistent methodology for reliable estimation of mixing enthalpies of liquid alloys.

  19. Estimating procedure times for surgeries by determining location parameters for the lognormal model.

    PubMed

    Spangler, William E; Strum, David P; Vargas, Luis G; May, Jerrold H

    2004-05-01

    We present an empirical study of methods for estimating the location parameter of the lognormal distribution. Our results identify the best order statistic to use, and indicate that using the best order statistic instead of the median may lead to less frequent incorrect rejection of the lognormal model, more accurate critical value estimates, and higher goodness-of-fit. Using simulation data, we constructed and compared two models for identifying the best order statistic, one based on conventional nonlinear regression and the other using a data mining/machine learning technique. Better surgical procedure time estimates may lead to improved surgical operations.

  20. Effect of correlated observation error on parameters, predictions, and uncertainty

    USGS Publications Warehouse

    Tiedeman, Claire; Green, Christopher T.

    2013-01-01

    Correlations among observation errors are typically omitted when calculating observation weights for model calibration by inverse methods. We explore the effects of omitting these correlations on estimates of parameters, predictions, and uncertainties. First, we develop a new analytical expression for the difference in parameter variance estimated with and without error correlations for a simple one-parameter two-observation inverse model. Results indicate that omitting error correlations from both the weight matrix and the variance calculation can either increase or decrease the parameter variance, depending on the values of error correlation (ρ) and the ratio of dimensionless scaled sensitivities (rdss). For small ρ, the difference in variance is always small, but for large ρ, the difference varies widely depending on the sign and magnitude of rdss. Next, we consider a groundwater reactive transport model of denitrification with four parameters and correlated geochemical observation errors that are computed by an error-propagation approach that is new for hydrogeologic studies. We compare parameter estimates, predictions, and uncertainties obtained with and without the error correlations. Omitting the correlations modestly to substantially changes parameter estimates, and causes both increases and decreases of parameter variances, consistent with the analytical expression. Differences in predictions for the models calibrated with and without error correlations can be greater than parameter differences when both are considered relative to their respective confidence intervals. These results indicate that including observation error correlations in weighting for nonlinear regression can have important effects on parameter estimates, predictions, and their respective uncertainties.

  1. Blood viscosity monitoring during cardiopulmonary bypass based on pressure-flow characteristics of a Newtonian fluid.

    PubMed

    Okahara, Shigeyuki; Zu Soh; Takahashi, Shinya; Sueda, Taijiro; Tsuji, Toshio

    2016-08-01

    We proposed a blood viscosity estimation method based on pressure-flow characteristics of oxygenators used during cardiopulmonary bypass (CPB) in a previous study that showed the estimated viscosity to correlate well with the measured viscosity. However, the determination of the parameters included in the method required the use of blood, thereby leading to high cost of calibration. Therefore, in this study we propose a new method to monitor blood viscosity, which approximates the pressure-flow characteristics of blood considered as a non-Newtonian fluid with characteristics of a Newtonian fluid by using the parameters derived from glycerin solution to enable ease of acquisition. Because parameters used in the estimation method are based on fluid types, bovine blood parameters were used to calculate estimated viscosity (ηe), and glycerin parameters were used to estimate deemed viscosity (ηdeem). Three samples of whole bovine blood with different hematocrit levels (21.8%, 31.0%, and 39.8%) were prepared and perfused into the oxygenator. As the temperature changed from 37 °C to 27 °C, the oxygenator mean inlet pressure and outlet pressure were recorded for flows of 2 L/min and 4 L/min, and the viscosity was estimated. The value of deemed viscosity calculated with the glycerin parameters was lower than estimated viscosity calculated with bovine blood parameters by 20-33% at 21.8% hematocrit, 12-27% at 31.0% hematocrit, and 10-15% at 39.8% hematocrit. Furthermore, deemed viscosity was lower than estimated viscosity by 10-30% at 2 L/min and 30-40% at 4 L/min. Nevertheless, estimated and deemed viscosities varied with a similar slope. Therefore, this shows that deemed viscosity achieved using glycerin parameters may be capable of successfully monitoring relative viscosity changes of blood in a perfusing oxygenator.

  2. Assessing the Uncertainties on Seismic Source Parameters: Towards Realistic Estimates of Moment Tensor Determinations

    NASA Astrophysics Data System (ADS)

    Magnoni, F.; Scognamiglio, L.; Tinti, E.; Casarotti, E.

    2014-12-01

    Seismic moment tensor is one of the most important source parameters defining the earthquake dimension and style of the activated fault. Moment tensor catalogues are ordinarily used by geoscientists, however, few attempts have been done to assess possible impacts of moment magnitude uncertainties upon their own analysis. The 2012 May 20 Emilia mainshock is a representative event since it is defined in literature with a moment magnitude value (Mw) spanning between 5.63 and 6.12. An uncertainty of ~0.5 units in magnitude leads to a controversial knowledge of the real size of the event. The possible uncertainty associated to this estimate could be critical for the inference of other seismological parameters, suggesting caution for seismic hazard assessment, coulomb stress transfer determination and other analyses where self-consistency is important. In this work, we focus on the variability of the moment tensor solution, highlighting the effect of four different velocity models, different types and ranges of filtering, and two different methodologies. Using a larger dataset, to better quantify the source parameter uncertainty, we also analyze the variability of the moment tensor solutions depending on the number, the epicentral distance and the azimuth of used stations. We endorse that the estimate of seismic moment from moment tensor solutions, as well as the estimate of the other kinematic source parameters, cannot be considered an absolute value and requires to come out with the related uncertainties and in a reproducible framework characterized by disclosed assumptions and explicit processing workflows.

  3. Developing a Novel Parameter Estimation Method for Agent-Based Model in Immune System Simulation under the Framework of History Matching: A Case Study on Influenza A Virus Infection

    PubMed Central

    Li, Tingting; Cheng, Zhengguo; Zhang, Le

    2017-01-01

    Since they can provide a natural and flexible description of nonlinear dynamic behavior of complex system, Agent-based models (ABM) have been commonly used for immune system simulation. However, it is crucial for ABM to obtain an appropriate estimation for the key parameters of the model by incorporating experimental data. In this paper, a systematic procedure for immune system simulation by integrating the ABM and regression method under the framework of history matching is developed. A novel parameter estimation method by incorporating the experiment data for the simulator ABM during the procedure is proposed. First, we employ ABM as simulator to simulate the immune system. Then, the dimension-reduced type generalized additive model (GAM) is employed to train a statistical regression model by using the input and output data of ABM and play a role as an emulator during history matching. Next, we reduce the input space of parameters by introducing an implausible measure to discard the implausible input values. At last, the estimation of model parameters is obtained using the particle swarm optimization algorithm (PSO) by fitting the experiment data among the non-implausible input values. The real Influeza A Virus (IAV) data set is employed to demonstrate the performance of our proposed method, and the results show that the proposed method not only has good fitting and predicting accuracy, but it also owns favorable computational efficiency. PMID:29194393

  4. Developing a Novel Parameter Estimation Method for Agent-Based Model in Immune System Simulation under the Framework of History Matching: A Case Study on Influenza A Virus Infection.

    PubMed

    Li, Tingting; Cheng, Zhengguo; Zhang, Le

    2017-12-01

    Since they can provide a natural and flexible description of nonlinear dynamic behavior of complex system, Agent-based models (ABM) have been commonly used for immune system simulation. However, it is crucial for ABM to obtain an appropriate estimation for the key parameters of the model by incorporating experimental data. In this paper, a systematic procedure for immune system simulation by integrating the ABM and regression method under the framework of history matching is developed. A novel parameter estimation method by incorporating the experiment data for the simulator ABM during the procedure is proposed. First, we employ ABM as simulator to simulate the immune system. Then, the dimension-reduced type generalized additive model (GAM) is employed to train a statistical regression model by using the input and output data of ABM and play a role as an emulator during history matching. Next, we reduce the input space of parameters by introducing an implausible measure to discard the implausible input values. At last, the estimation of model parameters is obtained using the particle swarm optimization algorithm (PSO) by fitting the experiment data among the non-implausible input values. The real Influeza A Virus (IAV) data set is employed to demonstrate the performance of our proposed method, and the results show that the proposed method not only has good fitting and predicting accuracy, but it also owns favorable computational efficiency.

  5. Transformation to equivalent dimensions—a new methodology to study earthquake clustering

    NASA Astrophysics Data System (ADS)

    Lasocki, Stanislaw

    2014-05-01

    A seismic event is represented by a point in a parameter space, quantified by the vector of parameter values. Studies of earthquake clustering involve considering distances between such points in multidimensional spaces. However, the metrics of earthquake parameters are different, hence the metric in a multidimensional parameter space cannot be readily defined. The present paper proposes a solution of this metric problem based on a concept of probabilistic equivalence of earthquake parameters. Under this concept the lengths of parameter intervals are equivalent if the probability for earthquakes to take values from either interval is the same. Earthquake clustering is studied in an equivalent rather than the original dimensions space, where the equivalent dimension (ED) of a parameter is its cumulative distribution function. All transformed parameters are of linear scale in [0, 1] interval and the distance between earthquakes represented by vectors in any ED space is Euclidean. The unknown, in general, cumulative distributions of earthquake parameters are estimated from earthquake catalogues by means of the model-free non-parametric kernel estimation method. Potential of the transformation to EDs is illustrated by two examples of use: to find hierarchically closest neighbours in time-space and to assess temporal variations of earthquake clustering in a specific 4-D phase space.

  6. Experimental design for estimating parameters of rate-limited mass transfer: Analysis of stream tracer studies

    USGS Publications Warehouse

    Wagner, Brian J.; Harvey, Judson W.

    1997-01-01

    Tracer experiments are valuable tools for analyzing the transport characteristics of streams and their interactions with shallow groundwater. The focus of this work is the design of tracer studies in high-gradient stream systems subject to advection, dispersion, groundwater inflow, and exchange between the active channel and zones in surface or subsurface water where flow is stagnant or slow moving. We present a methodology for (1) evaluating and comparing alternative stream tracer experiment designs and (2) identifying those combinations of stream transport properties that pose limitations to parameter estimation and therefore a challenge to tracer test design. The methodology uses the concept of global parameter uncertainty analysis, which couples solute transport simulation with parameter uncertainty analysis in a Monte Carlo framework. Two general conclusions resulted from this work. First, the solute injection and sampling strategy has an important effect on the reliability of transport parameter estimates. We found that constant injection with sampling through concentration rise, plateau, and fall provided considerably more reliable parameter estimates than a pulse injection across the spectrum of transport scenarios likely encountered in high-gradient streams. Second, for a given tracer test design, the uncertainties in mass transfer and storage-zone parameter estimates are strongly dependent on the experimental Damkohler number, DaI, which is a dimensionless combination of the rates of exchange between the stream and storage zones, the stream-water velocity, and the stream reach length of the experiment. Parameter uncertainties are lowest at DaI values on the order of 1.0. When DaI values are much less than 1.0 (owing to high velocity, long exchange timescale, and/or short reach length), parameter uncertainties are high because only a small amount of tracer interacts with storage zones in the reach. For the opposite conditions (DaI ≫ 1.0), solute exchange rates are fast relative to stream-water velocity and all solute is exchanged with the storage zone over the experimental reach. As DaI increases, tracer dispersion caused by hyporheic exchange eventually reaches an equilibrium condition and storage-zone exchange parameters become essentially nonidentifiable.

  7. Sensitivity of viscosity Arrhenius parameters to polarity of liquids

    NASA Astrophysics Data System (ADS)

    Kacem, R. B. H.; Alzamel, N. O.; Ouerfelli, N.

    2017-09-01

    Several empirical and semi-empirical equations have been proposed in the literature to estimate the liquid viscosity upon temperature. In this context, this paper aims to study the effect of polarity of liquids on the modeling of the viscosity-temperature dependence, considering particularly the Arrhenius type equations. To achieve this purpose, the solvents are classified into three groups: nonpolar, borderline polar and polar solvents. Based on adequate statistical tests, we found that there is strong evidence that the polarity of solvents affects significantly the distribution of the Arrhenius-type equation parameters and consequently the modeling of the viscosity-temperature dependence. Thus, specific estimated values of parameters for each group of liquids are proposed in this paper. In addition, the comparison of the accuracy of approximation with and without classification of liquids, using the Wilcoxon signed-rank test, shows a significant discrepancy of the borderline polar solvents. For that, we suggested in this paper new specific coefficient values of the simplified Arrhenius-type equation for better estimation accuracy. This result is important given that the accuracy in the estimation of the viscosity-temperature dependence may affect considerably the design and the optimization of several industrial processes.

  8. 3-D transient hydraulic tomography in unconfined aquifers with fast drainage response

    NASA Astrophysics Data System (ADS)

    Cardiff, M.; Barrash, W.

    2011-12-01

    We investigate, through numerical experiments, the viability of three-dimensional transient hydraulic tomography (3DTHT) for identifying the spatial distribution of groundwater flow parameters (primarily, hydraulic conductivity K) in permeable, unconfined aquifers. To invert the large amount of transient data collected from 3DTHT surveys, we utilize an iterative geostatistical inversion strategy in which outer iterations progressively increase the number of data points fitted and inner iterations solve the quasi-linear geostatistical formulas of Kitanidis. In order to base our numerical experiments around realistic scenarios, we utilize pumping rates, geometries, and test lengths similar to those attainable during 3DTHT field campaigns performed at the Boise Hydrogeophysical Research Site (BHRS). We also utilize hydrologic parameters that are similar to those observed at the BHRS and in other unconsolidated, unconfined fluvial aquifers. In addition to estimating K, we test the ability of 3DTHT to estimate both average storage values (specific storage Ss and specific yield Sy) as well as spatial variability in storage coefficients. The effects of model conceptualization errors during unconfined 3DTHT are investigated including: (1) assuming constant storage coefficients during inversion and (2) assuming stationary geostatistical parameter variability. Overall, our findings indicate that estimation of K is slightly degraded if storage parameters must be jointly estimated, but that this effect is quite small compared with the degradation of estimates due to violation of "structural" geostatistical assumptions. Practically, we find for our scenarios that assuming constant storage values during inversion does not appear to have a significant effect on K estimates or uncertainty bounds.

  9. Estimating skin blood saturation by selecting a subset of hyperspectral imaging data

    NASA Astrophysics Data System (ADS)

    Ewerlöf, Maria; Salerud, E. Göran; Strömberg, Tomas; Larsson, Marcus

    2015-03-01

    Skin blood haemoglobin saturation (?b) can be estimated with hyperspectral imaging using the wavelength (λ) range of 450-700 nm where haemoglobin absorption displays distinct spectral characteristics. Depending on the image size and photon transport algorithm, computations may be demanding. Therefore, this work aims to evaluate subsets with a reduced number of wavelengths for ?b estimation. White Monte Carlo simulations are performed using a two-layered tissue model with discrete values for epidermal thickness (?epi) and the reduced scattering coefficient (μ's ), mimicking an imaging setup. A detected intensity look-up table is calculated for a range of model parameter values relevant to human skin, adding absorption effects in the post-processing. Skin model parameters, including absorbers, are; μ's (λ), ?epi, haemoglobin saturation (?b), tissue fraction blood (?b) and tissue fraction melanin (?mel). The skin model paired with the look-up table allow spectra to be calculated swiftly. Three inverse models with varying number of free parameters are evaluated: A(?b, ?b), B(?b, ?b, ?mel) and C(all parameters free). Fourteen wavelength candidates are selected by analysing the maximal spectral sensitivity to ?b and minimizing the sensitivity to ?b. All possible combinations of these candidates with three, four and 14 wavelengths, as well as the full spectral range, are evaluated for estimating ?b for 1000 randomly generated evaluation spectra. The results show that the simplified models A and B estimated ?b accurately using four wavelengths (mean error 2.2% for model B). If the number of wavelengths increased, the model complexity needed to be increased to avoid poor estimations.

  10. Dynamical Analysis of an SEIT Epidemic Model with Application to Ebola Virus Transmission in Guinea.

    PubMed

    Li, Zhiming; Teng, Zhidong; Feng, Xiaomei; Li, Yingke; Zhang, Huiguo

    2015-01-01

    In order to investigate the transmission mechanism of the infectious individual with Ebola virus, we establish an SEIT (susceptible, exposed in the latent period, infectious, and treated/recovery) epidemic model. The basic reproduction number is defined. The mathematical analysis on the existence and stability of the disease-free equilibrium and endemic equilibrium is given. As the applications of the model, we use the recognized infectious and death cases in Guinea to estimate parameters of the model by the least square method. With suitable parameter values, we obtain the estimated value of the basic reproduction number and analyze the sensitivity and uncertainty property by partial rank correlation coefficients.

  11. Correlation of echocardiographic and hemodynamic parameters in pulmonary hypertension assessment prior to heart transplantation.

    PubMed

    Mogollón Jiménez, M V; Escoresca Ortega, A M; Cabeza Letrán, M L; Hinojosa Pérez, R; Lage Gallé, E; Sobrino Márquez, J M; Herruzo Avilés, A; Romero Rodríguez, N; Frutos López, M; Pérez de la Yglesia, R; Martínez Martínez, A

    2008-11-01

    Invasive assessment of pulmonary artery pressure (PAP), via right heart catheterization, is part of the usual protocol prior to heart transplantation. Echocardiography is considered a valuable technique to evaluate PAP. We sought to determine the reliability of measurements of PAP via a noninvasive technique, echocardiography, in relation to the estimated PAP via right catheterization. We also determined its safety when invasive procedures are restricted to just patients with pulmonary hypertension (PHT) according to echocardiographic parameters. We performed a retrospective study of 67 right catheterizations performed in our hospital, within the heart transplant study protocol, from January 2000 to December 2006. PAP parameters were estimated by echocardiography and right catheterization. Hemodynamically, 57.1% of the patients had severe PHT (more than 45 mm Hg mean PAP); 13.2% moderate PHT (between 35 and 45 mm Hg mean PAP); 12.1% had mild PHT (between 25 and 35 mm Hg mean PAP); and 17.6% of patients showed no PHT. Pearson correlation index with systolic PAP (estimated via echocardiography) and mean PAP (calculated via invasive method) was 0.69 (P < .001). PHT was considered significant when systolic PAP estimated via echocardiography reached more than 40 mm Hg and mean PAP estimated via right catheterization reached more than 35 mm Hg, the value from which the vasodilator test was carried out. According to these parameters, echocardiography showed a sensitivity of 89% to diagnose significant PHT and 46% specificity, with positive and negative predictive values of 70% and 76%, respectively.

  12. Optimal hemodynamic response model for functional near-infrared spectroscopy

    PubMed Central

    Kamran, Muhammad A.; Jeong, Myung Yung; Mannan, Malik M. N.

    2015-01-01

    Functional near-infrared spectroscopy (fNIRS) is an emerging non-invasive brain imaging technique and measures brain activities by means of near-infrared light of 650–950 nm wavelengths. The cortical hemodynamic response (HR) differs in attributes at different brain regions and on repetition of trials, even if the experimental paradigm is kept exactly the same. Therefore, an HR model that can estimate such variations in the response is the objective of this research. The canonical hemodynamic response function (cHRF) is modeled by two Gamma functions with six unknown parameters (four of them to model the shape and other two to scale and baseline respectively). The HRF model is supposed to be a linear combination of HRF, baseline, and physiological noises (amplitudes and frequencies of physiological noises are supposed to be unknown). An objective function is developed as a square of the residuals with constraints on 12 free parameters. The formulated problem is solved by using an iterative optimization algorithm to estimate the unknown parameters in the model. Inter-subject variations in HRF and physiological noises have been estimated for better cortical functional maps. The accuracy of the algorithm has been verified using 10 real and 15 simulated data sets. Ten healthy subjects participated in the experiment and their HRF for finger-tapping tasks have been estimated and analyzed. The statistical significance of the estimated activity strength parameters has been verified by employing statistical analysis (i.e., t-value > tcritical and p-value < 0.05). PMID:26136668

  13. Optimal hemodynamic response model for functional near-infrared spectroscopy.

    PubMed

    Kamran, Muhammad A; Jeong, Myung Yung; Mannan, Malik M N

    2015-01-01

    Functional near-infrared spectroscopy (fNIRS) is an emerging non-invasive brain imaging technique and measures brain activities by means of near-infrared light of 650-950 nm wavelengths. The cortical hemodynamic response (HR) differs in attributes at different brain regions and on repetition of trials, even if the experimental paradigm is kept exactly the same. Therefore, an HR model that can estimate such variations in the response is the objective of this research. The canonical hemodynamic response function (cHRF) is modeled by two Gamma functions with six unknown parameters (four of them to model the shape and other two to scale and baseline respectively). The HRF model is supposed to be a linear combination of HRF, baseline, and physiological noises (amplitudes and frequencies of physiological noises are supposed to be unknown). An objective function is developed as a square of the residuals with constraints on 12 free parameters. The formulated problem is solved by using an iterative optimization algorithm to estimate the unknown parameters in the model. Inter-subject variations in HRF and physiological noises have been estimated for better cortical functional maps. The accuracy of the algorithm has been verified using 10 real and 15 simulated data sets. Ten healthy subjects participated in the experiment and their HRF for finger-tapping tasks have been estimated and analyzed. The statistical significance of the estimated activity strength parameters has been verified by employing statistical analysis (i.e., t-value > t critical and p-value < 0.05).

  14. Analytical performance evaluation of SAR ATR with inaccurate or estimated models

    NASA Astrophysics Data System (ADS)

    DeVore, Michael D.

    2004-09-01

    Hypothesis testing algorithms for automatic target recognition (ATR) are often formulated in terms of some assumed distribution family. The parameter values corresponding to a particular target class together with the distribution family constitute a model for the target's signature. In practice such models exhibit inaccuracy because of incorrect assumptions about the distribution family and/or because of errors in the assumed parameter values, which are often determined experimentally. Model inaccuracy can have a significant impact on performance predictions for target recognition systems. Such inaccuracy often causes model-based predictions that ignore the difference between assumed and actual distributions to be overly optimistic. This paper reports on research to quantify the effect of inaccurate models on performance prediction and to estimate the effect using only trained parameters. We demonstrate that for large observation vectors the class-conditional probabilities of error can be expressed as a simple function of the difference between two relative entropies. These relative entropies quantify the discrepancies between the actual and assumed distributions and can be used to express the difference between actual and predicted error rates. Focusing on the problem of ATR from synthetic aperture radar (SAR) imagery, we present estimators of the probabilities of error in both ideal and plug-in tests expressed in terms of the trained model parameters. These estimators are defined in terms of unbiased estimates for the first two moments of the sample statistic. We present an analytical treatment of these results and include demonstrations from simulated radar data.

  15. Permeability estimations and frictional flow features passing through porous media comprised of structured microbeads

    NASA Astrophysics Data System (ADS)

    Shin, C.

    2017-12-01

    Permeability estimation has been extensively researched in diverse fields; however, methods that suitably consider varying geometries and changes within the flow region, for example, hydraulic fracture closing for several years, are yet to be developed. Therefore, in the present study a new permeability estimation method is presented based on the generalized Darcy's friction flow relation, in particular, by examining frictional flow parameters and characteristics of their variations. For this examination, computational fluid dynamics (CFD) simulations of simple hydraulic fractures filled with five layers of structured microbeads and accompanied by geometry changes and flow transitions are performed. Consequently, it was checked whether the main structures and shapes of each flow path are preserved, even for geometry variations within porous media. However, the scarcity and discontinuity of streamlines increase dramatically in the transient- and turbulent-flow regions. The quantitative and analytic examinations of the frictional flow features were also performed. Accordingly, the modified frictional flow parameters were successfully presented as similarity parameters of porous flows. In conclusion, the generalized Darcy's friction flow relation and friction equivalent permeability (FEP) equation were both modified using the similarity parameters. For verification, the FEP values of the other aperture models were estimated and then it was checked whether they agreed well with the original permeability values. Ultimately, the proposed and verified method is expected to efficiently estimate permeability variations in porous media with changing geometric factors and flow regions, including such instances as hydraulic fracture closings.

  16. Estimating parameters for probabilistic linkage of privacy-preserved datasets.

    PubMed

    Brown, Adrian P; Randall, Sean M; Ferrante, Anna M; Semmens, James B; Boyd, James H

    2017-07-10

    Probabilistic record linkage is a process used to bring together person-based records from within the same dataset (de-duplication) or from disparate datasets using pairwise comparisons and matching probabilities. The linkage strategy and associated match probabilities are often estimated through investigations into data quality and manual inspection. However, as privacy-preserved datasets comprise encrypted data, such methods are not possible. In this paper, we present a method for estimating the probabilities and threshold values for probabilistic privacy-preserved record linkage using Bloom filters. Our method was tested through a simulation study using synthetic data, followed by an application using real-world administrative data. Synthetic datasets were generated with error rates from zero to 20% error. Our method was used to estimate parameters (probabilities and thresholds) for de-duplication linkages. Linkage quality was determined by F-measure. Each dataset was privacy-preserved using separate Bloom filters for each field. Match probabilities were estimated using the expectation-maximisation (EM) algorithm on the privacy-preserved data. Threshold cut-off values were determined by an extension to the EM algorithm allowing linkage quality to be estimated for each possible threshold. De-duplication linkages of each privacy-preserved dataset were performed using both estimated and calculated probabilities. Linkage quality using the F-measure at the estimated threshold values was also compared to the highest F-measure. Three large administrative datasets were used to demonstrate the applicability of the probability and threshold estimation technique on real-world data. Linkage of the synthetic datasets using the estimated probabilities produced an F-measure that was comparable to the F-measure using calculated probabilities, even with up to 20% error. Linkage of the administrative datasets using estimated probabilities produced an F-measure that was higher than the F-measure using calculated probabilities. Further, the threshold estimation yielded results for F-measure that were only slightly below the highest possible for those probabilities. The method appears highly accurate across a spectrum of datasets with varying degrees of error. As there are few alternatives for parameter estimation, the approach is a major step towards providing a complete operational approach for probabilistic linkage of privacy-preserved datasets.

  17. State estimation bias induced by optimization under uncertainty and error cost asymmetry is likely reflected in perception.

    PubMed

    Shimansky, Y P

    2011-05-01

    It is well known from numerous studies that perception can be significantly affected by intended action in many everyday situations, indicating that perception and related decision-making is not a simple, one-way sequence, but a complex iterative cognitive process. However, the underlying functional mechanisms are yet unclear. Based on an optimality approach, a quantitative computational model of one such mechanism has been developed in this study. It is assumed in the model that significant uncertainty about task-related parameters of the environment results in parameter estimation errors and an optimal control system should minimize the cost of such errors in terms of the optimality criterion. It is demonstrated that, if the cost of a parameter estimation error is significantly asymmetrical with respect to error direction, the tendency to minimize error cost creates a systematic deviation of the optimal parameter estimate from its maximum likelihood value. Consequently, optimization of parameter estimate and optimization of control action cannot be performed separately from each other under parameter uncertainty combined with asymmetry of estimation error cost, thus making the certainty equivalence principle non-applicable under those conditions. A hypothesis that not only the action, but also perception itself is biased by the above deviation of parameter estimate is supported by ample experimental evidence. The results provide important insights into the cognitive mechanisms of interaction between sensory perception and planning an action under realistic conditions. Implications for understanding related functional mechanisms of optimal control in the CNS are discussed.

  18. Multiscale spatial and temporal estimation of the b-value

    NASA Astrophysics Data System (ADS)

    García-Hernández, R.; D'Auria, L.; Barrancos, J.; Padilla, G.

    2017-12-01

    The estimation of the spatial and temporal variations of the Gutenberg-Richter b-value is of great importance in different seismological applications. One of the problems affecting its estimation is the heterogeneous distribution of the seismicity which makes its estimate strongly dependent upon the selected spatial and/or temporal scale. This is especially important in volcanoes where dense clusters of earthquakes often overlap the background seismicity. Proposed solutions for estimating temporal variations of the b-value include considering equally spaced time intervals or variable intervals having an equal number of earthquakes. Similar approaches have been proposed to image the spatial variations of this parameter as well.We propose a novel multiscale approach, based on the method of Ogata and Katsura (1993), allowing a consistent estimation of the b-value regardless of the considered spatial and/or temporal scales. Our method, named MUST-B (MUltiscale Spatial and Temporal characterization of the B-value), basically consists in computing estimates of the b-value at multiple temporal and spatial scales, extracting for a give spatio-temporal point a statistical estimator of the value, as well as and indication of the characteristic spatio-temporal scale. This approach includes also a consistent estimation of the completeness magnitude (Mc) and of the uncertainties over both b and Mc.We applied this method to example datasets for volcanic (Tenerife, El Hierro) and tectonic areas (Central Italy) as well as an example application at global scale.

  19. Reliability measurement for mixed mode failures of 33/11 kilovolt electric power distribution stations.

    PubMed

    Alwan, Faris M; Baharum, Adam; Hassan, Geehan S

    2013-01-01

    The reliability of the electrical distribution system is a contemporary research field due to diverse applications of electricity in everyday life and diverse industries. However a few research papers exist in literature. This paper proposes a methodology for assessing the reliability of 33/11 Kilovolt high-power stations based on average time between failures. The objective of this paper is to find the optimal fit for the failure data via time between failures. We determine the parameter estimation for all components of the station. We also estimate the reliability value of each component and the reliability value of the system as a whole. The best fitting distribution for the time between failures is a three parameter Dagum distribution with a scale parameter [Formula: see text] and shape parameters [Formula: see text] and [Formula: see text]. Our analysis reveals that the reliability value decreased by 38.2% in each 30 days. We believe that the current paper is the first to address this issue and its analysis. Thus, the results obtained in this research reflect its originality. We also suggest the practicality of using these results for power systems for both the maintenance of power systems models and preventive maintenance models.

  20. Reliability Measurement for Mixed Mode Failures of 33/11 Kilovolt Electric Power Distribution Stations

    PubMed Central

    Alwan, Faris M.; Baharum, Adam; Hassan, Geehan S.

    2013-01-01

    The reliability of the electrical distribution system is a contemporary research field due to diverse applications of electricity in everyday life and diverse industries. However a few research papers exist in literature. This paper proposes a methodology for assessing the reliability of 33/11 Kilovolt high-power stations based on average time between failures. The objective of this paper is to find the optimal fit for the failure data via time between failures. We determine the parameter estimation for all components of the station. We also estimate the reliability value of each component and the reliability value of the system as a whole. The best fitting distribution for the time between failures is a three parameter Dagum distribution with a scale parameter and shape parameters and . Our analysis reveals that the reliability value decreased by 38.2% in each 30 days. We believe that the current paper is the first to address this issue and its analysis. Thus, the results obtained in this research reflect its originality. We also suggest the practicality of using these results for power systems for both the maintenance of power systems models and preventive maintenance models. PMID:23936346

  1. Estimated snow parameters for vehicle mobility modeling in Korea, Germany and interior Alaska

    DOT National Transportation Integrated Search

    1995-09-01

    Snow is a crucial factor affecting the U.S. Army's operations in cold regions. Values for snow depth and snow density are needed for vehicle mobility studies, but unfortunately the available historical records of these parameters tend to be relativel...

  2. Uncertainty Quantification of Equilibrium Climate Sensitivity in CCSM4

    NASA Astrophysics Data System (ADS)

    Covey, C. C.; Lucas, D. D.; Tannahill, J.; Klein, R.

    2013-12-01

    Uncertainty in the global mean equilibrium surface warming due to doubled atmospheric CO2, as computed by a "slab ocean" configuration of the Community Climate System Model version 4 (CCSM4), is quantified using 1,039 perturbed-input-parameter simulations. The slab ocean configuration reduces the model's e-folding time when approaching an equilibrium state to ~5 years. This time is much less than for the full ocean configuration, consistent with the shallow depth of the upper well-mixed layer of the ocean represented by the "slab." Adoption of the slab ocean configuration requires the assumption of preset values for the convergence of ocean heat transport beneath the upper well-mixed layer. A standard procedure for choosing these values maximizes agreement with the full ocean version's simulation of the present-day climate when input parameters assume their default values. For each new set of input parameter values, we computed the change in ocean heat transport implied by a "Phase 1" model run in which sea surface temperatures and sea ice concentrations were set equal to present-day values. The resulting total ocean heat transport (= standard value + change implied by Phase 1 run) was then input into "Phase 2" slab ocean runs with varying values of atmospheric CO2. Our uncertainty estimate is based on Latin Hypercube sampling over expert-provided uncertainty ranges of N = 36 adjustable parameters in the atmosphere (CAM4) and sea ice (CICE4) components of CCSM4. Two-dimensional projections of our sampling distribution for the N(N-1)/2 possible pairs of input parameters indicate full coverage of the N-dimensional parameter space, including edges. We used a machine learning-based support vector regression (SVR) statistical model to estimate the probability density function (PDF) of equilibrium warming. This fitting procedure produces a PDF that is qualitatively consistent with the raw histogram of our CCSM4 results. Most of the values from the SVR statistical model are within ~0.1 K of the raw results, well below the inter-decile range inferred below. Independent validation of the fit indicates residual errors that are distributed about zero with a standard deviation of 0.17 K. Analysis of variance shows that the equilibrium warming in CCSM4 is mainly linear in parameter changes. Thus, in accord with the Central Limit Theorem of statistics, the PDF of the warming is approximately Gaussian, i.e. symmetric about its mean value (3.0 K). Since SVR allows for highly nonlinear fits, the symmetry is not an artifact of the fitting procedure. The 10-90 percentile range of the PDF is 2.6-3.4 K, consistent with earlier estimates from CCSM4 but narrower than estimates from other models, which sometimes produce a high-temperature asymmetric tail in the PDF. This work was performed under auspices of the US Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344, and was funded by LLNL's Uncertainty Quantification Strategic Initiative (Laboratory Directed Research and Development Project 10-SI-013).

  3. Method for Calculating the Optical Diffuse Reflection Coefficient for the Ocular Fundus

    NASA Astrophysics Data System (ADS)

    Lisenko, S. A.; Kugeiko, M. M.

    2016-07-01

    We have developed a method for calculating the optical diffuse reflection coefficient for the ocular fundus, taking into account multiple scattering of light in its layers (retina, epithelium, choroid) and multiple refl ection of light between layers. The method is based on the formulas for optical "combination" of the layers of the medium, in which the optical parameters of the layers (absorption and scattering coefficients) are replaced by some effective values, different for cases of directional and diffuse illumination of the layer. Coefficients relating the effective optical parameters of the layers and the actual values were established based on the results of a Monte Carlo numerical simulation of radiation transport in the medium. We estimate the uncertainties in retrieval of the structural and morphological parameters for the fundus from its diffuse reflectance spectrum using our method. We show that the simulated spectra correspond to the experimental data and that the estimates of the fundus parameters obtained as a result of solving the inverse problem are reasonable.

  4. Nonlinear Curve-Fitting Program

    NASA Technical Reports Server (NTRS)

    Everhart, Joel L.; Badavi, Forooz F.

    1989-01-01

    Nonlinear optimization algorithm helps in finding best-fit curve. Nonlinear Curve Fitting Program, NLINEAR, interactive curve-fitting routine based on description of quadratic expansion of X(sup 2) statistic. Utilizes nonlinear optimization algorithm calculating best statistically weighted values of parameters of fitting function and X(sup 2) minimized. Provides user with such statistical information as goodness of fit and estimated values of parameters producing highest degree of correlation between experimental data and mathematical model. Written in FORTRAN 77.

  5. Upper-Bound Radiation Dose Assessment for Military Personnel at McMurdo Station, Antarctica, between 1962 and 1979

    DTIC Science & Technology

    2013-06-01

    Belvoir, VA 22060-6201 10. SPONSOR/MONITOR’S ACRONYM(S) DTRA J9-NTSN 11 . SPONSORING/MONITORING AGENCY REPORT NUMBER DTRA-TR-12-003 12...average tritium activity in drinking water samples (Bq L-1) ......................... 43 Table 11 . Parameter values and assumptions for estimating...the ground, roads and ship loading areas .......................... 59 11 Table 23. Parameter values and assumptions for the internal dose from

  6. Parameter estimation for a cohesive sediment transport model by assimilating satellite observations in the Hangzhou Bay: Temporal variations and spatial distributions

    NASA Astrophysics Data System (ADS)

    Wang, Daosheng; Zhang, Jicai; He, Xianqiang; Chu, Dongdong; Lv, Xianqing; Wang, Ya Ping; Yang, Yang; Fan, Daidu; Gao, Shu

    2018-01-01

    Model parameters in the suspended cohesive sediment transport models are critical for the accurate simulation of suspended sediment concentrations (SSCs). Difficulties in estimating the model parameters still prevent numerical modeling of the sediment transport from achieving a high level of predictability. Based on a three-dimensional cohesive sediment transport model and its adjoint model, the satellite remote sensing data of SSCs during both spring tide and neap tide, retrieved from Geostationary Ocean Color Imager (GOCI), are assimilated to synchronously estimate four spatially and temporally varying parameters in the Hangzhou Bay in China, including settling velocity, resuspension rate, inflow open boundary conditions and initial conditions. After data assimilation, the model performance is significantly improved. Through several sensitivity experiments, the spatial and temporal variation tendencies of the estimated model parameters are verified to be robust and not affected by model settings. The pattern for the variations of the estimated parameters is analyzed and summarized. The temporal variations and spatial distributions of the estimated settling velocity are negatively correlated with current speed, which can be explained using the combination of flocculation process and Stokes' law. The temporal variations and spatial distributions of the estimated resuspension rate are also negatively correlated with current speed, which are related to the grain size of the seabed sediments under different current velocities. Besides, the estimated inflow open boundary conditions reach the local maximum values near the low water slack conditions and the estimated initial conditions are negatively correlated with water depth, which is consistent with the general understanding. The relationships between the estimated parameters and the hydrodynamic fields can be suggestive for improving the parameterization in cohesive sediment transport models.

  7. Errors in the estimation method for the rejection of vibrations in adaptive optics systems

    NASA Astrophysics Data System (ADS)

    Kania, Dariusz

    2017-06-01

    In recent years the problem of the mechanical vibrations impact in adaptive optics (AO) systems has been renewed. These signals are damped sinusoidal signals and have deleterious effect on the system. One of software solutions to reject the vibrations is an adaptive method called AVC (Adaptive Vibration Cancellation) where the procedure has three steps: estimation of perturbation parameters, estimation of the frequency response of the plant, update the reference signal to reject/minimalize the vibration. In the first step a very important problem is the estimation method. A very accurate and fast (below 10 ms) estimation method of these three parameters has been presented in several publications in recent years. The method is based on using the spectrum interpolation and MSD time windows and it can be used to estimate multifrequency signals. In this paper the estimation method is used in the AVC method to increase the system performance. There are several parameters that affect the accuracy of obtained results, e.g. CiR - number of signal periods in a measurement window, N - number of samples in the FFT procedure, H - time window order, SNR, b - number of ADC bits, γ - damping ratio of the tested signal. Systematic errors increase when N, CiR, H decrease and when γ increases. The value for systematic error is approximately 10^-10 Hz/Hz for N = 2048 and CiR = 0.1. This paper presents equations that can used to estimate maximum systematic errors for given values of H, CiR and N before the start of the estimation process.

  8. Volume effects of late term normal tissue toxicity in prostate cancer radiotherapy

    NASA Astrophysics Data System (ADS)

    Bonta, Dacian Viorel

    Modeling of volume effects for treatment toxicity is paramount for optimization of radiation therapy. This thesis proposes a new model for calculating volume effects in gastro-intestinal and genito-urinary normal tissue complication probability (NTCP) following radiation therapy for prostate carcinoma. The radiobiological and the pathological basis for this model and its relationship to other models are detailed. A review of the radiobiological experiments and published clinical data identified salient features and specific properties a biologically adequate model has to conform to. The new model was fit to a set of actual clinical data. In order to verify the goodness of fit, two established NTCP models and a non-NTCP measure for complication risk were fitted to the same clinical data. The method of fit for the model parameters was maximum likelihood estimation. Within the framework of the maximum likelihood approach I estimated the parameter uncertainties for each complication prediction model. The quality-of-fit was determined using the Aikaike Information Criterion. Based on the model that provided the best fit, I identified the volume effects for both types of toxicities. Computer-based bootstrap resampling of the original dataset was used to estimate the bias and variance for the fitted parameter values. Computer simulation was also used to estimate the population size that generates a specific uncertainty level (3%) in the value of predicted complication probability. The same method was used to estimate the size of the patient population needed for accurate choice of the model underlying the NTCP. The results indicate that, depending on the number of parameters of a specific NTCP model, 100 (for two parameter models) and 500 patients (for three parameter models) are needed for accurate parameter fit. Correlation of complication occurrence in patients was also investigated. The results suggest that complication outcomes are correlated in a patient, although the correlation coefficient is rather small.

  9. Normal Values for Heart Electrophysiology Parameters of Healthy Swine Determined on Electrophysiology Study.

    PubMed

    Noszczyk-Nowak, Agnieszka; Cepiel, Alicja; Janiszewski, Adrian; Pasławski, Robert; Gajek, Jacek; Pasławska, Urszula; Nicpoń, Józef

    2016-01-01

    Swine are a well-recognized animal model for human cardiovascular diseases. Despite the widespread use of porcine model in experimental electrophysiology, still no reference values for intracardiac electrical activity and conduction parameters determined during an invasive electrophysiology study (EPS) have been developed in this species thus far. The aim of the study was to develop a set of normal values for intracardiac electrical activity and conduction parameters determined during an invasive EPS of swine. The study included 36 healthy domestic swine (24-40 kg body weight). EPS was performed under a general anesthesia with midazolam, propofol and isoflurane. The reference values for intracardiac electrical activity and conduction parameters were calculated as arithmetic means ± 2 standard deviations. The reference values were determined for AH, HV and PA intervals, interatrial conduction time at its own and imposed rhythm, sinus node recovery time (SNRT), corrected sinus node recovery time (CSNRT), anterograde and retrograde Wenckebach points, atrial, atrioventricular node and ventricular refractory periods. No significant correlations were found between body weight and heart rate of the examined pigs and their electrophysiological parameters. The hereby presented reference values can be helpful in comparing the results of various studies, as well as in more accurately estimating the values of electrophysiological parameters that can be expected in a given experiment.

  10. Theoretical Analysis of Spacing Parameters of Anisotropic 3D Surface Roughness

    NASA Astrophysics Data System (ADS)

    Rudzitis, J.; Bulaha, N.; Lungevics, J.; Linins, O.; Berzins, K.

    2017-04-01

    The authors of the research have analysed spacing parameters of anisotropic 3D surface roughness crosswise to machining (friction) traces RSm1 and lengthwise to machining (friction) traces RSm2. The main issue arises from the RSm2 values being limited by values of sampling length l in the measuring devices; however, on many occasions RSm2 values can exceed l values. Therefore, the mean spacing values of profile irregularities in the longitudinal direction in many cases are not reliable and they should be determined by another method. Theoretically, it is proved that anisotropic surface roughness anisotropy coefficient c=RSm1/RSm2 equals texture aspect ratio Str, which is determined by surface texture standard EN ISO 25178-2. This allows using parameter Str to determine mean spacing of profile irregularities and estimate roughness anisotropy.

  11. Logistic regression for circular data

    NASA Astrophysics Data System (ADS)

    Al-Daffaie, Kadhem; Khan, Shahjahan

    2017-05-01

    This paper considers the relationship between a binary response and a circular predictor. It develops the logistic regression model by employing the linear-circular regression approach. The maximum likelihood method is used to estimate the parameters. The Newton-Raphson numerical method is used to find the estimated values of the parameters. A data set from weather records of Toowoomba city is analysed by the proposed methods. Moreover, a simulation study is considered. The R software is used for all computations and simulations.

  12. Value-based decision-making battery: A Bayesian adaptive approach to assess impulsive and risky behavior.

    PubMed

    Pooseh, Shakoor; Bernhardt, Nadine; Guevara, Alvaro; Huys, Quentin J M; Smolka, Michael N

    2018-02-01

    Using simple mathematical models of choice behavior, we present a Bayesian adaptive algorithm to assess measures of impulsive and risky decision making. Practically, these measures are characterized by discounting rates and are used to classify individuals or population groups, to distinguish unhealthy behavior, and to predict developmental courses. However, a constant demand for improved tools to assess these constructs remains unanswered. The algorithm is based on trial-by-trial observations. At each step, a choice is made between immediate (certain) and delayed (risky) options. Then the current parameter estimates are updated by the likelihood of observing the choice, and the next offers are provided from the indifference point, so that they will acquire the most informative data based on the current parameter estimates. The procedure continues for a certain number of trials in order to reach a stable estimation. The algorithm is discussed in detail for the delay discounting case, and results from decision making under risk for gains, losses, and mixed prospects are also provided. Simulated experiments using prescribed parameter values were performed to justify the algorithm in terms of the reproducibility of its parameters for individual assessments, and to test the reliability of the estimation procedure in a group-level analysis. The algorithm was implemented as an experimental battery to measure temporal and probability discounting rates together with loss aversion, and was tested on a healthy participant sample.

  13. Optimum data weighting and error calibration for estimation of gravitational parameters

    NASA Technical Reports Server (NTRS)

    Lerch, Francis J.

    1989-01-01

    A new technique was developed for the weighting of data from satellite tracking systems in order to obtain an optimum least-squares solution and an error calibration for the solution parameters. Data sets from optical, electronic, and laser systems on 17 satellites in GEM-T1 Goddard Earth Model-T1 (GEM-T1) were employed toward application of this technique for gravity field parameters. Also GEM-T2 (31 satellites) was recently computed as a direct application of the method and is summarized. The method employs subset solutions of the data associated with the complete solution to agree with their error estimates. With the adjusted weights the process provides for an automatic calibration of the error estimates for the solution parameters. The data weights derived are generally much smaller than corresponding weights obtained from nominal values of observation accuracy or residuals. Independent tests show significant improvement for solutions with optimal weighting. The technique is general and may be applied to orbit parameters, station coordinates, or other parameters than the gravity model.

  14. Maximum likelihood estimation for life distributions with competing failure modes

    NASA Technical Reports Server (NTRS)

    Sidik, S. M.

    1979-01-01

    Systems which are placed on test at time zero, function for a period and die at some random time were studied. Failure may be due to one of several causes or modes. The parameters of the life distribution may depend upon the levels of various stress variables the item is subject to. Maximum likelihood estimation methods are discussed. Specific methods are reported for the smallest extreme-value distributions of life. Monte-Carlo results indicate the methods to be promising. Under appropriate conditions, the location parameters are nearly unbiased, the scale parameter is slight biased, and the asymptotic covariances are rapidly approached.

  15. Estimation of Inertial Parameters of Rigid Body Links of Manipulators.

    DTIC Science & Technology

    1986-02-01

    H AN ET RL. FED 86 UNCLRSSIFIED Al-H-88? NSSI4-8- C -O5OS F/ O 13/13 ML mmmmmmmmuhmhEMENOMONEE 1248 = . I 2.2. 36I W 11111 1.0 112.0 ~ Lm 11111 1111 25l...good match was obtained between joint [lror uesq’pre;Act om the estimated parameters and the joint torques computed A" rn fu~ S. C b.. .:. Massachusetts...value o , which if not zero indicates that linear combination of parameters, vYO, is identifiable. Since K is a function only of the geometry of the

  16. Examples of Nonconservatism in the CARE 3 Program

    NASA Technical Reports Server (NTRS)

    Dotson, Kelly J.

    1988-01-01

    This paper presents parameter regions in the CARE 3 (Computer-Aided Reliability Estimation version 3) computer program where the program overestimates the reliability of a modeled system without warning the user. Five simple models of fault-tolerant computer systems are analyzed; and, the parameter regions where reliability is overestimated are given. The source of the error in the reliability estimates for models which incorporate transient fault occurrences was not readily apparent. However, the source of much of the error for models with permanent and intermittent faults can be attributed to the choice of values for the run-time parameters of the program.

  17. Transfer-function-parameter estimation from frequency response data: A FORTRAN program

    NASA Technical Reports Server (NTRS)

    Seidel, R. C.

    1975-01-01

    A FORTRAN computer program designed to fit a linear transfer function model to given frequency response magnitude and phase data is presented. A conjugate gradient search is used that minimizes the integral of the absolute value of the error squared between the model and the data. The search is constrained to insure model stability. A scaling of the model parameters by their own magnitude aids search convergence. Efficient computer algorithms result in a small and fast program suitable for a minicomputer. A sample problem with different model structures and parameter estimates is reported.

  18. An empirical analysis of the distribution of the duration of overshoots in a stationary gaussian stochastic process

    NASA Technical Reports Server (NTRS)

    Parrish, R. S.; Carter, M. C.

    1974-01-01

    This analysis utilizes computer simulation and statistical estimation. Realizations of stationary gaussian stochastic processes with selected autocorrelation functions are computer simulated. Analysis of the simulated data revealed that the mean and the variance of a process were functionally dependent upon the autocorrelation parameter and crossing level. Using predicted values for the mean and standard deviation, by the method of moments, the distribution parameters was estimated. Thus, given the autocorrelation parameter, crossing level, mean, and standard deviation of a process, the probability of exceeding the crossing level for a particular length of time was calculated.

  19. Trans-dimensional inversion of microtremor array dispersion data with hierarchical autoregressive error models

    NASA Astrophysics Data System (ADS)

    Dettmer, Jan; Molnar, Sheri; Steininger, Gavin; Dosso, Stan E.; Cassidy, John F.

    2012-02-01

    This paper applies a general trans-dimensional Bayesian inference methodology and hierarchical autoregressive data-error models to the inversion of microtremor array dispersion data for shear wave velocity (vs) structure. This approach accounts for the limited knowledge of the optimal earth model parametrization (e.g. the number of layers in the vs profile) and of the data-error statistics in the resulting vs parameter uncertainty estimates. The assumed earth model parametrization influences estimates of parameter values and uncertainties due to different parametrizations leading to different ranges of data predictions. The support of the data for a particular model is often non-unique and several parametrizations may be supported. A trans-dimensional formulation accounts for this non-uniqueness by including a model-indexing parameter as an unknown so that groups of models (identified by the indexing parameter) are considered in the results. The earth model is parametrized in terms of a partition model with interfaces given over a depth-range of interest. In this work, the number of interfaces (layers) in the partition model represents the trans-dimensional model indexing. In addition, serial data-error correlations are addressed by augmenting the geophysical forward model with a hierarchical autoregressive error model that can account for a wide range of error processes with a small number of parameters. Hence, the limited knowledge about the true statistical distribution of data errors is also accounted for in the earth model parameter estimates, resulting in more realistic uncertainties and parameter values. Hierarchical autoregressive error models do not rely on point estimates of the model vector to estimate data-error statistics, and have no requirement for computing the inverse or determinant of a data-error covariance matrix. This approach is particularly useful for trans-dimensional inverse problems, as point estimates may not be representative of the state space that spans multiple subspaces of different dimensionalities. The order of the autoregressive process required to fit the data is determined here by posterior residual-sample examination and statistical tests. Inference for earth model parameters is carried out on the trans-dimensional posterior probability distribution by considering ensembles of parameter vectors. In particular, vs uncertainty estimates are obtained by marginalizing the trans-dimensional posterior distribution in terms of vs-profile marginal distributions. The methodology is applied to microtremor array dispersion data collected at two sites with significantly different geology in British Columbia, Canada. At both sites, results show excellent agreement with estimates from invasive measurements.

  20. 40 CFR 98.195 - Procedures for estimating missing data.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Procedures for estimating missing data... estimating missing data. For the procedure in § 98.193(b)(1), a complete record of all measured parameters... available process data or data used for accounting purposes. (b) For missing values related to the CaO and...

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